CIG75_RS20195 245a187fadf50b6bf4d48f0b9142249f 535 Pfam PF06418 CTP synthase N-terminus 3 265 4.0E-130 T 28-03-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 CIG75_RS20195 245a187fadf50b6bf4d48f0b9142249f 535 Gene3D G3DSA:3.40.50.880 287 535 1.8E-72 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CIG75_RS20195 245a187fadf50b6bf4d48f0b9142249f 535 Pfam PF00117 Glutamine amidotransferase class-I 302 527 9.1E-57 T 28-03-2018 IPR017926 Glutamine amidotransferase CIG75_RS20195 245a187fadf50b6bf4d48f0b9142249f 535 SUPERFAMILY SSF52540 1 270 1.24E-126 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS20195 245a187fadf50b6bf4d48f0b9142249f 535 TIGRFAM TIGR00337 PyrG: CTP synthase 2 527 6.7E-260 T 28-03-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 CIG75_RS20195 245a187fadf50b6bf4d48f0b9142249f 535 Gene3D G3DSA:3.40.50.300 1 286 2.0E-134 T 28-03-2018 CIG75_RS20195 245a187fadf50b6bf4d48f0b9142249f 535 SUPERFAMILY SSF52317 290 533 8.19E-85 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CIG75_RS20195 245a187fadf50b6bf4d48f0b9142249f 535 Hamap MF_01227 CTP synthase [pyrG]. 2 532 52.995 T 28-03-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 CIG75_RS05510 aebfd6991d4574532204cb068d8141a4 437 Pfam PF07085 DRTGG domain 77 179 5.2E-27 T 28-03-2018 IPR010766 DRTGG KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CIG75_RS05510 aebfd6991d4574532204cb068d8141a4 437 Gene3D G3DSA:1.10.10.10 1 69 3.9E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS05510 aebfd6991d4574532204cb068d8141a4 437 SUPERFAMILY SSF75138 73 186 3.27E-26 T 28-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like CIG75_RS05510 aebfd6991d4574532204cb068d8141a4 437 SMART SM00116 260 307 1.2E-6 T 28-03-2018 IPR000644 CBS domain CIG75_RS05510 aebfd6991d4574532204cb068d8141a4 437 SMART SM00116 197 249 2.3 T 28-03-2018 IPR000644 CBS domain CIG75_RS05510 aebfd6991d4574532204cb068d8141a4 437 Gene3D G3DSA:3.10.580.10 191 301 1.0E-23 T 28-03-2018 CIG75_RS05510 aebfd6991d4574532204cb068d8141a4 437 SUPERFAMILY SSF54631 183 309 3.28E-28 T 28-03-2018 CIG75_RS05510 aebfd6991d4574532204cb068d8141a4 437 Pfam PF00571 CBS domain 254 306 1.0E-6 T 28-03-2018 IPR000644 CBS domain CIG75_RS05510 aebfd6991d4574532204cb068d8141a4 437 Pfam PF00571 CBS domain 202 245 6.6E-5 T 28-03-2018 IPR000644 CBS domain CIG75_RS05510 aebfd6991d4574532204cb068d8141a4 437 Gene3D G3DSA:3.40.1390.20 70 190 4.1E-25 T 28-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like CIG75_RS05510 aebfd6991d4574532204cb068d8141a4 437 Pfam PF03061 Thioesterase superfamily 354 423 7.0E-10 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CIG75_RS05510 aebfd6991d4574532204cb068d8141a4 437 SUPERFAMILY SSF46785 4 60 1.66E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS05510 aebfd6991d4574532204cb068d8141a4 437 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 60 2.9E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CIG75_RS05510 aebfd6991d4574532204cb068d8141a4 437 Gene3D G3DSA:3.10.129.10 302 437 1.6E-25 T 28-03-2018 CIG75_RS05510 aebfd6991d4574532204cb068d8141a4 437 SUPERFAMILY SSF54637 304 431 4.21E-18 T 28-03-2018 IPR029069 HotDog domain CIG75_RS03690 03264d6491aea199f2ffc93e75323b90 670 SUPERFAMILY SSF56091 2 314 9.18E-92 T 28-03-2018 CIG75_RS03690 03264d6491aea199f2ffc93e75323b90 670 Gene3D G3DSA:1.10.150.20 549 613 1.9E-10 T 28-03-2018 CIG75_RS03690 03264d6491aea199f2ffc93e75323b90 670 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 4 663 1.7E-202 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CIG75_RS03690 03264d6491aea199f2ffc93e75323b90 670 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 594 667 1.5E-12 T 28-03-2018 IPR001357 BRCT domain CIG75_RS03690 03264d6491aea199f2ffc93e75323b90 670 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 321 389 1.2E-24 T 28-03-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 CIG75_RS03690 03264d6491aea199f2ffc93e75323b90 670 Gene3D G3DSA:1.10.150.20 428 499 1.6E-21 T 28-03-2018 CIG75_RS03690 03264d6491aea199f2ffc93e75323b90 670 PIRSF PIRSF001604 1 670 5.9E-211 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CIG75_RS03690 03264d6491aea199f2ffc93e75323b90 670 Gene3D G3DSA:1.10.287.610 1 59 1.3E-16 T 28-03-2018 CIG75_RS03690 03264d6491aea199f2ffc93e75323b90 670 SMART SM00278 541 560 0.42 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CIG75_RS03690 03264d6491aea199f2ffc93e75323b90 670 SMART SM00278 477 496 0.024 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CIG75_RS03690 03264d6491aea199f2ffc93e75323b90 670 Pfam PF14520 Helix-hairpin-helix domain 451 498 1.6E-4 T 28-03-2018 CIG75_RS03690 03264d6491aea199f2ffc93e75323b90 670 SUPERFAMILY SSF50249 317 391 1.54E-20 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CIG75_RS03690 03264d6491aea199f2ffc93e75323b90 670 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 330 345 - T 28-03-2018 IPR033136 NAD-dependent DNA ligase, conserved site CIG75_RS03690 03264d6491aea199f2ffc93e75323b90 670 Gene3D G3DSA:3.30.1490.70 193 320 2.1E-22 T 28-03-2018 CIG75_RS03690 03264d6491aea199f2ffc93e75323b90 670 Gene3D G3DSA:3.30.1490.70 74 171 3.4E-14 T 28-03-2018 CIG75_RS03690 03264d6491aea199f2ffc93e75323b90 670 SMART SM00292 593 670 2.4E-15 T 28-03-2018 IPR001357 BRCT domain CIG75_RS03690 03264d6491aea199f2ffc93e75323b90 670 Hamap MF_01588 DNA ligase [ligA]. 1 667 43.172 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CIG75_RS03690 03264d6491aea199f2ffc93e75323b90 670 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 2 317 4.1E-92 T 28-03-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 CIG75_RS03690 03264d6491aea199f2ffc93e75323b90 670 SUPERFAMILY SSF52113 593 667 2.8E-19 T 28-03-2018 IPR001357 BRCT domain CIG75_RS03690 03264d6491aea199f2ffc93e75323b90 670 SMART SM00532 1 444 6.4E-162 T 28-03-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 CIG75_RS03690 03264d6491aea199f2ffc93e75323b90 670 Pfam PF12826 Helix-hairpin-helix motif 508 570 6.5E-20 T 28-03-2018 CIG75_RS03690 03264d6491aea199f2ffc93e75323b90 670 Gene3D G3DSA:2.40.50.140 321 388 4.1E-25 T 28-03-2018 CIG75_RS03690 03264d6491aea199f2ffc93e75323b90 670 SUPERFAMILY SSF47781 403 580 2.19E-52 T 28-03-2018 IPR010994 RuvA domain 2-like CIG75_RS03690 03264d6491aea199f2ffc93e75323b90 670 Gene3D G3DSA:3.40.50.10190 614 670 2.8E-16 T 28-03-2018 IPR001357 BRCT domain CIG75_RS03690 03264d6491aea199f2ffc93e75323b90 670 Gene3D G3DSA:1.10.150.20 500 548 1.1E-20 T 28-03-2018 CIG75_RS07000 5255c5328692a609bcdffa3a03f5cd5d 233 PRINTS PR00046 Major sigma-70 factor signature 212 223 2.0E-14 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS07000 5255c5328692a609bcdffa3a03f5cd5d 233 PRINTS PR00046 Major sigma-70 factor signature 78 91 2.0E-14 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS07000 5255c5328692a609bcdffa3a03f5cd5d 233 PRINTS PR00046 Major sigma-70 factor signature 197 212 2.0E-14 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS07000 5255c5328692a609bcdffa3a03f5cd5d 233 PRINTS PR00046 Major sigma-70 factor signature 176 188 2.0E-14 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS07000 5255c5328692a609bcdffa3a03f5cd5d 233 SUPERFAMILY SSF88946 8 122 2.49E-34 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS07000 5255c5328692a609bcdffa3a03f5cd5d 233 Gene3D G3DSA:1.10.601.10 17 121 3.7E-28 T 28-03-2018 CIG75_RS07000 5255c5328692a609bcdffa3a03f5cd5d 233 SUPERFAMILY SSF88659 139 229 5.79E-21 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS07000 5255c5328692a609bcdffa3a03f5cd5d 233 Gene3D G3DSA:1.10.1270.10 144 233 8.4E-21 T 28-03-2018 CIG75_RS07000 5255c5328692a609bcdffa3a03f5cd5d 233 TIGRFAM TIGR02846 spore_sigmaK: RNA polymerase sigma-K factor 6 227 8.6E-111 T 28-03-2018 IPR014209 RNA polymerase sigma-K type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS07000 5255c5328692a609bcdffa3a03f5cd5d 233 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 78 91 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS07000 5255c5328692a609bcdffa3a03f5cd5d 233 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 197 223 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS07000 5255c5328692a609bcdffa3a03f5cd5d 233 PIRSF PIRSF000770 3 233 3.1E-82 T 28-03-2018 CIG75_RS07000 5255c5328692a609bcdffa3a03f5cd5d 233 Pfam PF04542 Sigma-70 region 2 54 123 1.3E-16 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS07000 5255c5328692a609bcdffa3a03f5cd5d 233 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 50 227 1.7E-31 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS07000 5255c5328692a609bcdffa3a03f5cd5d 233 Pfam PF04545 Sigma-70, region 4 174 223 8.5E-17 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Gene3D G3DSA:3.40.50.980 3428 3580 8.1E-25 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Gene3D G3DSA:3.40.50.980 5544 5703 6.3E-36 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Gene3D G3DSA:3.40.50.980 4479 4637 2.1E-24 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Gene3D G3DSA:3.40.50.980 173 344 1.8E-32 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Gene3D G3DSA:3.40.50.980 1331 1484 2.7E-28 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Gene3D G3DSA:3.40.50.980 6607 6771 1.2E-38 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Gene3D G3DSA:3.40.50.980 7676 7839 1.3E-36 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Gene3D G3DSA:3.40.50.980 2379 2536 1.4E-27 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 SUPERFAMILY SSF52777 3870 4047 8.34E-47 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 SUPERFAMILY SSF52777 890 1168 1.22E-51 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 SUPERFAMILY SSF56801 3242 3794 7.33E-153 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 SUPERFAMILY SSF56801 4291 4857 6.8E-150 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 SUPERFAMILY SSF56801 5385 5920 1.07E-135 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 SUPERFAMILY SSF56801 2190 2747 1.07E-159 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 SUPERFAMILY SSF52777 7067 7244 9.23E-52 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Gene3D G3DSA:3.40.50.980 6 172 8.9E-38 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Gene3D G3DSA:3.40.50.980 1174 1330 3.6E-49 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Gene3D G3DSA:3.40.50.980 5382 5543 1.1E-31 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Gene3D G3DSA:3.40.50.980 6450 6606 7.7E-51 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Gene3D G3DSA:3.40.50.980 2222 2378 5.3E-46 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Gene3D G3DSA:3.40.50.980 3275 3427 2.6E-46 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Gene3D G3DSA:3.40.50.980 4326 4478 6.4E-44 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Gene3D G3DSA:3.40.50.980 7522 7675 2.4E-47 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 ProSitePatterns PS00455 Putative AMP-binding domain signature. 4473 4484 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 SUPERFAMILY SSF47336 2727 2800 1.83E-19 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 SUPERFAMILY SSF47336 8027 8100 7.72E-21 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Pfam PF00668 Condensation domain 3866 4313 1.4E-122 T 28-03-2018 IPR001242 Condensation domain CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Pfam PF00668 Condensation domain 2816 3264 4.1E-125 T 28-03-2018 IPR001242 Condensation domain CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Pfam PF00668 Condensation domain 7065 7509 1.2E-117 T 28-03-2018 IPR001242 Condensation domain CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Pfam PF00668 Condensation domain 5992 6440 1.3E-117 T 28-03-2018 IPR001242 Condensation domain CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Pfam PF00668 Condensation domain 1768 2211 2.9E-115 T 28-03-2018 IPR001242 Condensation domain CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Pfam PF00668 Condensation domain 4934 5370 1.5E-106 T 28-03-2018 IPR001242 Condensation domain CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Pfam PF00668 Condensation domain 707 1163 7.7E-92 T 28-03-2018 IPR001242 Condensation domain CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 ProSitePatterns PS00012 Phosphopantetheine attachment site. 8059 8074 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 ProSitePatterns PS00012 Phosphopantetheine attachment site. 7000 7015 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 SUPERFAMILY SSF56801 6419 6988 2.22E-169 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 SUPERFAMILY SSF47336 611 720 5.23E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Pfam PF00501 AMP-binding enzyme 6459 6864 1.3E-107 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Pfam PF00501 AMP-binding enzyme 7529 7926 4.7E-107 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Pfam PF00501 AMP-binding enzyme 4332 4732 3.9E-89 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Pfam PF00501 AMP-binding enzyme 3285 3672 2.1E-93 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Pfam PF00501 AMP-binding enzyme 2231 2627 6.3E-96 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Pfam PF00501 AMP-binding enzyme 14 461 6.7E-87 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Pfam PF00501 AMP-binding enzyme 1183 1575 1.7E-99 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Pfam PF00501 AMP-binding enzyme 5393 5797 9.8E-81 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 SUPERFAMILY SSF52777 4053 4320 3.78E-69 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Pfam PF00550 Phosphopantetheine attachment site 3784 3846 4.4E-16 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Pfam PF00550 Phosphopantetheine attachment site 2737 2800 5.7E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Pfam PF00550 Phosphopantetheine attachment site 6979 7040 1.9E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Pfam PF00550 Phosphopantetheine attachment site 620 684 2.6E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Pfam PF00550 Phosphopantetheine attachment site 4848 4910 1.6E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Pfam PF00550 Phosphopantetheine attachment site 5909 5970 7.1E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Pfam PF00550 Phosphopantetheine attachment site 1682 1744 7.3E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Pfam PF00550 Phosphopantetheine attachment site 8036 8100 3.7E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 SUPERFAMILY SSF52777 2822 2999 4.45E-50 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Gene3D G3DSA:2.30.38.10 7840 7916 9.0E-23 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Gene3D G3DSA:2.30.38.10 2537 2617 9.4E-24 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 ProSitePatterns PS00455 Putative AMP-binding domain signature. 7670 7681 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Pfam PF13193 AMP-binding enzyme C-terminal domain 4740 4818 7.1E-12 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Pfam PF13193 AMP-binding enzyme C-terminal domain 2635 2710 9.4E-14 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Pfam PF13193 AMP-binding enzyme C-terminal domain 7934 8008 8.5E-10 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Pfam PF13193 AMP-binding enzyme C-terminal domain 5805 5880 2.8E-10 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Pfam PF13193 AMP-binding enzyme C-terminal domain 1583 1656 5.0E-10 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Pfam PF13193 AMP-binding enzyme C-terminal domain 3680 3754 1.5E-10 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Pfam PF13193 AMP-binding enzyme C-terminal domain 6872 6947 2.3E-14 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 SUPERFAMILY SSF52777 1770 1947 9.12E-51 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2252 2651 1.7E-131 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 6480 6888 7.2E-140 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 3305 3696 9.9E-130 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 4353 4756 9.3E-127 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 7549 7950 4.2E-125 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 5412 5821 1.4E-104 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1204 1599 1.6E-132 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 SUPERFAMILY SSF52777 6182 6423 2.89E-65 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 SUPERFAMILY SSF47336 5900 5972 8.11E-20 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 SUPERFAMILY SSF56801 7489 8047 3.53E-163 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1325 1336 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 SUPERFAMILY SSF52777 5997 6174 6.56E-48 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 ProSitePatterns PS00455 Putative AMP-binding domain signature. 3422 3433 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Gene3D G3DSA:3.30.300.30 5792 5912 2.3E-36 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Gene3D G3DSA:3.30.300.30 2622 2740 9.1E-38 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Gene3D G3DSA:3.30.300.30 7921 8040 3.3E-39 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Gene3D G3DSA:3.30.300.30 4727 4850 4.1E-38 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Gene3D G3DSA:3.30.300.30 3667 3787 2.2E-41 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Gene3D G3DSA:3.30.300.30 6859 6981 1.7E-41 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Gene3D G3DSA:3.30.300.30 1570 1686 4.1E-40 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 SUPERFAMILY SSF52777 710 883 6.11E-35 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Gene3D G3DSA:1.10.1200.10 6982 7047 2.7E-21 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Gene3D G3DSA:1.10.1200.10 4851 4917 1.4E-24 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Gene3D G3DSA:1.10.1200.10 5913 5978 2.3E-21 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Gene3D G3DSA:1.10.1200.10 2741 2797 1.8E-22 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 SUPERFAMILY SSF47336 1673 1746 2.22E-19 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2373 2384 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 SUPERFAMILY SSF52777 1955 2216 1.22E-65 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 ProSitePatterns PS00455 Putative AMP-binding domain signature. 6601 6612 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 SUPERFAMILY SSF52777 4936 5111 2.45E-52 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 SUPERFAMILY SSF56801 6 564 4.58E-117 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 SMART SM01294 618 684 0.0088 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 SUPERFAMILY SSF47336 3773 3846 7.2E-21 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 SUPERFAMILY SSF52777 3007 3271 4.67E-69 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 SMART SM00823 Phosphopantetheine attachment site 1681 1750 0.0027 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 SMART SM00823 Phosphopantetheine attachment site 4845 4914 1.2E-5 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 SMART SM00823 Phosphopantetheine attachment site 3781 3850 3.8E-7 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 SMART SM00823 Phosphopantetheine attachment site 2735 2804 0.0014 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 SMART SM00823 Phosphopantetheine attachment site 8035 8104 3.5E-7 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 SMART SM00823 Phosphopantetheine attachment site 617 688 7.8E-11 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 SMART SM00823 Phosphopantetheine attachment site 5907 5976 1.8E-4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 SMART SM00823 Phosphopantetheine attachment site 6976 7045 0.0019 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Gene3D G3DSA:1.10.1200.10 8041 8117 4.4E-24 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Gene3D G3DSA:1.10.1200.10 3788 3853 5.0E-22 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Gene3D G3DSA:1.10.1200.10 1687 1756 1.5E-20 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 ProSitePatterns PS00455 Putative AMP-binding domain signature. 5538 5549 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 SUPERFAMILY SSF47336 4837 4910 7.33E-21 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4869 4884 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 SUPERFAMILY SSF52777 5117 5356 7.23E-58 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Gene3D G3DSA:3.30.559.10 5984 6175 8.1E-40 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Gene3D G3DSA:3.30.559.10 694 893 1.2E-31 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Gene3D G3DSA:3.30.559.10 4920 5117 1.2E-41 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Gene3D G3DSA:3.30.559.10 3854 4057 1.0E-40 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Gene3D G3DSA:2.30.38.10 5707 5790 2.6E-17 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Gene3D G3DSA:2.30.38.10 1485 1568 1.1E-23 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Gene3D G3DSA:2.30.38.10 6775 6857 3.7E-22 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Gene3D G3DSA:2.30.38.10 3581 3665 1.7E-23 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Gene3D G3DSA:2.30.38.10 372 453 2.6E-19 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Gene3D G3DSA:2.30.38.10 4643 4725 1.7E-23 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Gene3D G3DSA:3.30.559.10 7048 7267 2.2E-51 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Gene3D G3DSA:3.30.559.10 2798 3024 6.0E-50 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Gene3D G3DSA:3.30.559.10 1757 1969 1.5E-49 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 SUPERFAMILY SSF56801 1140 1693 1.28E-158 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 SUPERFAMILY SSF52777 7252 7496 5.56E-64 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Gene3D G3DSA:1.10.1200.10 602 693 2.0E-14 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 Gene3D G3DSA:3.30.300.30 454 562 2.9E-18 T 28-03-2018 CIG75_RS10305 a8258fec3f1b1bb2f2f5f78e4d74fa0f 8128 SUPERFAMILY SSF47336 6970 7041 1.03E-19 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS05210 49d2a0523c8f8f7361986bb1ff961f75 125 Gene3D G3DSA:3.40.50.2300 4 124 2.2E-6 T 28-03-2018 CIG75_RS05210 49d2a0523c8f8f7361986bb1ff961f75 125 SUPERFAMILY SSF52172 9 111 7.95E-6 T 28-03-2018 IPR011006 CheY-like superfamily CIG75_RS13025 236d5c5277322354beee72d9c71471e6 1063 Gene3D G3DSA:1.10.1030.10 403 531 1.8E-46 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CIG75_RS13025 236d5c5277322354beee72d9c71471e6 1063 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1062 13.446 T 28-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CIG75_RS13025 236d5c5277322354beee72d9c71471e6 1063 Gene3D G3DSA:3.30.470.20 120 401 1.0E-65 T 28-03-2018 CIG75_RS13025 236d5c5277322354beee72d9c71471e6 1063 SUPERFAMILY SSF52440 549 668 4.32E-49 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CIG75_RS13025 236d5c5277322354beee72d9c71471e6 1063 SUPERFAMILY SSF52440 1 127 5.18E-50 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CIG75_RS13025 236d5c5277322354beee72d9c71471e6 1063 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 423 540 1.7E-37 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CIG75_RS13025 236d5c5277322354beee72d9c71471e6 1063 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1058 13.102 T 28-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CIG75_RS13025 236d5c5277322354beee72d9c71471e6 1063 Gene3D G3DSA:3.40.50.20 532 647 1.3E-60 T 28-03-2018 CIG75_RS13025 236d5c5277322354beee72d9c71471e6 1063 SMART SM00851 950 1037 5.4E-29 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CIG75_RS13025 236d5c5277322354beee72d9c71471e6 1063 Gene3D G3DSA:3.40.50.20 4 117 1.5E-39 T 28-03-2018 CIG75_RS13025 236d5c5277322354beee72d9c71471e6 1063 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CIG75_RS13025 236d5c5277322354beee72d9c71471e6 1063 Gene3D G3DSA:3.40.50.1380 929 1057 7.2E-38 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CIG75_RS13025 236d5c5277322354beee72d9c71471e6 1063 SUPERFAMILY SSF56059 128 399 3.01E-108 T 28-03-2018 CIG75_RS13025 236d5c5277322354beee72d9c71471e6 1063 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 296 303 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CIG75_RS13025 236d5c5277322354beee72d9c71471e6 1063 SMART SM01209 672 836 0.0026 T 28-03-2018 CIG75_RS13025 236d5c5277322354beee72d9c71471e6 1063 Pfam PF02142 MGS-like domain 951 1037 3.2E-20 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CIG75_RS13025 236d5c5277322354beee72d9c71471e6 1063 SUPERFAMILY SSF52335 930 1052 3.01E-33 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CIG75_RS13025 236d5c5277322354beee72d9c71471e6 1063 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 830 837 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CIG75_RS13025 236d5c5277322354beee72d9c71471e6 1063 SMART SM01096 420 540 2.7E-58 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CIG75_RS13025 236d5c5277322354beee72d9c71471e6 1063 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 5.3E-62 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CIG75_RS13025 236d5c5277322354beee72d9c71471e6 1063 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 5.3E-62 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CIG75_RS13025 236d5c5277322354beee72d9c71471e6 1063 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 378 396 5.3E-62 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CIG75_RS13025 236d5c5277322354beee72d9c71471e6 1063 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 296 325 5.3E-62 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CIG75_RS13025 236d5c5277322354beee72d9c71471e6 1063 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 5.3E-62 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CIG75_RS13025 236d5c5277322354beee72d9c71471e6 1063 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 5.3E-62 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CIG75_RS13025 236d5c5277322354beee72d9c71471e6 1063 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 5.3E-62 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CIG75_RS13025 236d5c5277322354beee72d9c71471e6 1063 SUPERFAMILY SSF48108 394 546 3.4E-45 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CIG75_RS13025 236d5c5277322354beee72d9c71471e6 1063 Gene3D G3DSA:3.30.1490.20 648 737 1.4E-18 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CIG75_RS13025 236d5c5277322354beee72d9c71471e6 1063 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 3 1048 0.0 T 28-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CIG75_RS13025 236d5c5277322354beee72d9c71471e6 1063 SUPERFAMILY SSF56059 666 928 1.94E-98 T 28-03-2018 CIG75_RS13025 236d5c5277322354beee72d9c71471e6 1063 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 702 716 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CIG75_RS13025 236d5c5277322354beee72d9c71471e6 1063 Gene3D G3DSA:3.30.470.20 738 928 1.9E-36 T 28-03-2018 CIG75_RS13025 236d5c5277322354beee72d9c71471e6 1063 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 333 3.0E-82 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CIG75_RS13025 236d5c5277322354beee72d9c71471e6 1063 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 666 866 3.7E-38 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CIG75_RS12080 6bb9b85a29be59053f9cc6fc6015867b 136 TIGRFAM TIGR01396 FlgB: flagellar basal-body rod protein FlgB 6 131 1.9E-37 T 28-03-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 CIG75_RS12080 6bb9b85a29be59053f9cc6fc6015867b 136 PIRSF PIRSF002889 1 134 3.9E-40 T 28-03-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 CIG75_RS12080 6bb9b85a29be59053f9cc6fc6015867b 136 Pfam PF00460 Flagella basal body rod protein 16 39 2.7E-9 T 28-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 CIG75_RS08350 ab16924b80c4fbe00e296506d94c4cad 332 SMART SM00729 11 218 2.7E-16 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CIG75_RS08350 ab16924b80c4fbe00e296506d94c4cad 332 Pfam PF04055 Radical SAM superfamily 15 176 3.2E-34 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CIG75_RS08350 ab16924b80c4fbe00e296506d94c4cad 332 Pfam PF13353 4Fe-4S single cluster domain 18 103 6.6E-8 T 28-03-2018 CIG75_RS08350 ab16924b80c4fbe00e296506d94c4cad 332 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 17 28 - T 28-03-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 Reactome: R-HSA-947581 CIG75_RS08350 ab16924b80c4fbe00e296506d94c4cad 332 SUPERFAMILY SSF102114 2 277 2.88E-79 T 28-03-2018 CIG75_RS08350 ab16924b80c4fbe00e296506d94c4cad 332 Gene3D G3DSA:3.20.20.70 1 332 2.7E-91 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CIG75_RS08350 ab16924b80c4fbe00e296506d94c4cad 332 Pfam PF06463 Molybdenum Cofactor Synthesis C 183 308 5.8E-36 T 28-03-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 Reactome: R-HSA-947581 CIG75_RS08350 ab16924b80c4fbe00e296506d94c4cad 332 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 2 332 1.8E-119 T 28-03-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 Reactome: R-HSA-947581 CIG75_RS08350 ab16924b80c4fbe00e296506d94c4cad 332 Hamap MF_01225_B GTP 3',8-cyclase [moaA]. 2 332 39.692 T 28-03-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 Reactome: R-HSA-947581 CIG75_RS02990 4e089c9f9a2be2585f7cebe9ef179922 355 Gene3D G3DSA:3.40.190.10 36 150 3.1E-6 T 28-03-2018 CIG75_RS02990 4e089c9f9a2be2585f7cebe9ef179922 355 SUPERFAMILY SSF53850 40 355 1.85E-79 T 28-03-2018 CIG75_RS02990 4e089c9f9a2be2585f7cebe9ef179922 355 PIRSF PIRSF002825 1 355 1.5E-89 T 28-03-2018 IPR026045 Ferric binding protein CIG75_RS02990 4e089c9f9a2be2585f7cebe9ef179922 355 Pfam PF13343 Bacterial extracellular solute-binding protein 90 332 3.6E-28 T 28-03-2018 CIG75_RS02990 4e089c9f9a2be2585f7cebe9ef179922 355 Gene3D G3DSA:3.40.190.10 151 317 4.0E-36 T 28-03-2018 CIG75_RS03350 f7ffb4744e3828cd0cba725008b41d8a 2314 SUPERFAMILY SSF47336 994 1104 6.81E-21 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS03350 f7ffb4744e3828cd0cba725008b41d8a 2314 SUPERFAMILY SSF47336 2049 2122 1.3E-20 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS03350 f7ffb4744e3828cd0cba725008b41d8a 2314 SUPERFAMILY SSF52777 211 452 8.12E-64 T 28-03-2018 CIG75_RS03350 f7ffb4744e3828cd0cba725008b41d8a 2314 Gene3D G3DSA:3.30.559.10 2173 2313 8.4E-7 T 28-03-2018 CIG75_RS03350 f7ffb4744e3828cd0cba725008b41d8a 2314 Gene3D G3DSA:3.30.559.10 18 226 3.3E-43 T 28-03-2018 CIG75_RS03350 f7ffb4744e3828cd0cba725008b41d8a 2314 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2081 2096 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS03350 f7ffb4744e3828cd0cba725008b41d8a 2314 SUPERFAMILY SSF56801 1514 2070 5.76E-164 T 28-03-2018 CIG75_RS03350 f7ffb4744e3828cd0cba725008b41d8a 2314 Gene3D G3DSA:2.30.38.10 1862 1941 3.4E-23 T 28-03-2018 CIG75_RS03350 f7ffb4744e3828cd0cba725008b41d8a 2314 Gene3D G3DSA:2.30.38.10 799 881 2.1E-22 T 28-03-2018 CIG75_RS03350 f7ffb4744e3828cd0cba725008b41d8a 2314 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1697 1708 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS03350 f7ffb4744e3828cd0cba725008b41d8a 2314 SUPERFAMILY SSF52777 1094 1271 5.0E-50 T 28-03-2018 CIG75_RS03350 f7ffb4744e3828cd0cba725008b41d8a 2314 Gene3D G3DSA:1.10.1200.10 1007 1072 3.1E-25 T 28-03-2018 CIG75_RS03350 f7ffb4744e3828cd0cba725008b41d8a 2314 SUPERFAMILY SSF52777 28 204 7.67E-51 T 28-03-2018 CIG75_RS03350 f7ffb4744e3828cd0cba725008b41d8a 2314 Gene3D G3DSA:3.30.559.10 1073 1277 1.5E-43 T 28-03-2018 CIG75_RS03350 f7ffb4744e3828cd0cba725008b41d8a 2314 Gene3D G3DSA:3.40.50.980 480 637 1.2E-48 T 28-03-2018 CIG75_RS03350 f7ffb4744e3828cd0cba725008b41d8a 2314 Gene3D G3DSA:3.30.300.30 1943 2062 3.8E-40 T 28-03-2018 CIG75_RS03350 f7ffb4744e3828cd0cba725008b41d8a 2314 Gene3D G3DSA:3.30.300.30 886 1006 2.7E-41 T 28-03-2018 CIG75_RS03350 f7ffb4744e3828cd0cba725008b41d8a 2314 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1576 1972 2.5E-133 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS03350 f7ffb4744e3828cd0cba725008b41d8a 2314 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 510 915 8.8E-124 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS03350 f7ffb4744e3828cd0cba725008b41d8a 2314 SUPERFAMILY SSF52777 1276 1543 1.45E-65 T 28-03-2018 CIG75_RS03350 f7ffb4744e3828cd0cba725008b41d8a 2314 SMART SM00823 Phosphopantetheine attachment site 1001 1070 2.8E-6 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS03350 f7ffb4744e3828cd0cba725008b41d8a 2314 SMART SM00823 Phosphopantetheine attachment site 2057 2126 1.8E-5 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS03350 f7ffb4744e3828cd0cba725008b41d8a 2314 Pfam PF00501 AMP-binding enzyme 489 891 1.2E-91 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS03350 f7ffb4744e3828cd0cba725008b41d8a 2314 Pfam PF00501 AMP-binding enzyme 1555 1948 3.2E-101 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS03350 f7ffb4744e3828cd0cba725008b41d8a 2314 SUPERFAMILY SSF52777 2171 2310 1.33E-13 T 28-03-2018 CIG75_RS03350 f7ffb4744e3828cd0cba725008b41d8a 2314 Pfam PF13193 AMP-binding enzyme C-terminal domain 1956 2030 2.7E-14 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS03350 f7ffb4744e3828cd0cba725008b41d8a 2314 Pfam PF13193 AMP-binding enzyme C-terminal domain 899 974 5.3E-10 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS03350 f7ffb4744e3828cd0cba725008b41d8a 2314 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1025 1040 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS03350 f7ffb4744e3828cd0cba725008b41d8a 2314 Pfam PF00668 Condensation domain 1090 1536 2.1E-120 T 28-03-2018 IPR001242 Condensation domain CIG75_RS03350 f7ffb4744e3828cd0cba725008b41d8a 2314 Pfam PF00668 Condensation domain 25 468 1.1E-116 T 28-03-2018 IPR001242 Condensation domain CIG75_RS03350 f7ffb4744e3828cd0cba725008b41d8a 2314 Pfam PF00668 Condensation domain 2172 2310 9.5E-13 T 28-03-2018 IPR001242 Condensation domain CIG75_RS03350 f7ffb4744e3828cd0cba725008b41d8a 2314 Gene3D G3DSA:3.40.50.980 1702 1860 4.7E-33 T 28-03-2018 CIG75_RS03350 f7ffb4744e3828cd0cba725008b41d8a 2314 Gene3D G3DSA:3.40.50.980 638 796 1.8E-27 T 28-03-2018 CIG75_RS03350 f7ffb4744e3828cd0cba725008b41d8a 2314 Pfam PF00550 Phosphopantetheine attachment site 1003 1063 8.2E-17 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS03350 f7ffb4744e3828cd0cba725008b41d8a 2314 Pfam PF00550 Phosphopantetheine attachment site 2058 2121 6.7E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS03350 f7ffb4744e3828cd0cba725008b41d8a 2314 Gene3D G3DSA:3.40.50.980 1548 1701 2.3E-49 T 28-03-2018 CIG75_RS03350 f7ffb4744e3828cd0cba725008b41d8a 2314 ProSitePatterns PS00455 Putative AMP-binding domain signature. 631 642 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS03350 f7ffb4744e3828cd0cba725008b41d8a 2314 Gene3D G3DSA:1.10.1200.10 2063 2172 1.2E-23 T 28-03-2018 CIG75_RS03350 f7ffb4744e3828cd0cba725008b41d8a 2314 SUPERFAMILY SSF56801 447 1014 1.83E-156 T 28-03-2018 CIG75_RS13985 881d9463dc8a21cd8f25940301f24cc1 163 SUPERFAMILY SSF53155 4 83 5.3E-16 T 28-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CIG75_RS13985 881d9463dc8a21cd8f25940301f24cc1 163 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 5 74 1.8E-6 T 28-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CIG75_RS13985 881d9463dc8a21cd8f25940301f24cc1 163 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 79 159 8.3E-31 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CIG75_RS13985 881d9463dc8a21cd8f25940301f24cc1 163 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 7 159 36.984 T 28-03-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 CIG75_RS13985 881d9463dc8a21cd8f25940301f24cc1 163 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 78 158 6.0E-33 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CIG75_RS13985 881d9463dc8a21cd8f25940301f24cc1 163 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 128 134 - T 28-03-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CIG75_RS13985 881d9463dc8a21cd8f25940301f24cc1 163 SUPERFAMILY SSF46767 77 159 1.31E-29 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CIG75_RS13985 881d9463dc8a21cd8f25940301f24cc1 163 Gene3D G3DSA:3.30.160.70 1 73 9.5E-16 T 28-03-2018 CIG75_RS13985 881d9463dc8a21cd8f25940301f24cc1 163 Gene3D G3DSA:1.10.10.10 74 161 4.3E-32 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS09635 eb6726b1a23aa58dee85245aba849476 245 SUPERFAMILY SSF53335 7 230 1.32E-43 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CIG75_RS09635 eb6726b1a23aa58dee85245aba849476 245 Pfam PF01209 ubiE/COQ5 methyltransferase family 5 236 2.6E-83 T 28-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 CIG75_RS09635 eb6726b1a23aa58dee85245aba849476 245 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 22 37 - T 28-03-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 CIG75_RS09635 eb6726b1a23aa58dee85245aba849476 245 Gene3D G3DSA:3.40.50.150 6 239 3.2E-37 T 28-03-2018 CIG75_RS09635 eb6726b1a23aa58dee85245aba849476 245 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 144 158 - T 28-03-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 CIG75_RS09635 eb6726b1a23aa58dee85245aba849476 245 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 11 236 2.6E-74 T 28-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 CIG75_RS09635 eb6726b1a23aa58dee85245aba849476 245 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 2 236 34.711 T 28-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 CIG75_RS18035 8e4558bdf835c67e87a62b65ad5dbd64 304 SUPERFAMILY SSF55785 23 125 5.06E-24 T 28-03-2018 IPR000014 PAS domain CIG75_RS18035 8e4558bdf835c67e87a62b65ad5dbd64 304 Gene3D G3DSA:1.10.287.950 128 304 2.1E-35 T 28-03-2018 CIG75_RS18035 8e4558bdf835c67e87a62b65ad5dbd64 304 SUPERFAMILY SSF58104 108 301 4.05E-43 T 28-03-2018 CIG75_RS18035 8e4558bdf835c67e87a62b65ad5dbd64 304 Pfam PF08448 PAS fold 25 129 1.1E-14 T 28-03-2018 IPR013656 PAS fold-4 CIG75_RS18035 8e4558bdf835c67e87a62b65ad5dbd64 304 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 18 134 2.4E-15 T 28-03-2018 IPR000014 PAS domain CIG75_RS18035 8e4558bdf835c67e87a62b65ad5dbd64 304 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 158 298 1.9E-31 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CIG75_RS18035 8e4558bdf835c67e87a62b65ad5dbd64 304 SMART SM00086 86 128 0.0019 T 28-03-2018 IPR001610 PAC motif CIG75_RS18035 8e4558bdf835c67e87a62b65ad5dbd64 304 SMART SM00283 111 301 8.1E-5 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CIG75_RS18035 8e4558bdf835c67e87a62b65ad5dbd64 304 Gene3D G3DSA:3.40.50.10600 6 127 2.1E-26 T 28-03-2018 CIG75_RS06930 b67fe88d8c7a13229510c28b28f9b8b3 177 SUPERFAMILY SSF52833 1 176 7.48E-62 T 28-03-2018 IPR012336 Thioredoxin-like fold CIG75_RS06930 b67fe88d8c7a13229510c28b28f9b8b3 177 Gene3D G3DSA:3.30.1020.10 154 177 5.7E-7 T 28-03-2018 CIG75_RS06930 b67fe88d8c7a13229510c28b28f9b8b3 177 Pfam PF00578 AhpC/TSA family 4 138 1.5E-38 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CIG75_RS06930 b67fe88d8c7a13229510c28b28f9b8b3 177 Gene3D G3DSA:3.40.30.10 1 153 2.6E-38 T 28-03-2018 CIG75_RS06930 b67fe88d8c7a13229510c28b28f9b8b3 177 PIRSF PIRSF000239 1 177 5.1E-60 T 28-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CIG75_RS17800 33bef2e7bc51136b9ea78debfdf442a4 126 Gene3D G3DSA:1.10.3450.10 1 116 7.1E-25 T 28-03-2018 IPR023203 TTHA0068-like domain CIG75_RS17800 33bef2e7bc51136b9ea78debfdf442a4 126 Pfam PF03745 Domain of unknown function (DUF309) 6 65 2.9E-18 T 28-03-2018 IPR005500 Protein of unknown function DUF309 CIG75_RS17800 33bef2e7bc51136b9ea78debfdf442a4 126 SUPERFAMILY SSF140663 5 100 1.96E-25 T 28-03-2018 IPR023203 TTHA0068-like domain CIG75_RS01890 39f0f9604f3bf77cf59a53b3e1d65339 209 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 3 209 1.5E-88 T 28-03-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 CIG75_RS01890 39f0f9604f3bf77cf59a53b3e1d65339 209 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 3 209 47.47 T 28-03-2018 IPR034332 Uracil phosphoribosyltransferase, bacterial-type KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 CIG75_RS01890 39f0f9604f3bf77cf59a53b3e1d65339 209 SUPERFAMILY SSF53271 4 207 1.11E-72 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CIG75_RS01890 39f0f9604f3bf77cf59a53b3e1d65339 209 Gene3D G3DSA:3.40.50.2020 2 207 4.6E-65 T 28-03-2018 CIG75_RS01890 39f0f9604f3bf77cf59a53b3e1d65339 209 Pfam PF14681 Uracil phosphoribosyltransferase 6 208 6.3E-75 T 28-03-2018 CIG75_RS17295 52fa36772a1b49b0ea320a241abb04e9 482 Gene3D G3DSA:3.40.109.10 222 479 1.3E-24 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CIG75_RS17295 52fa36772a1b49b0ea320a241abb04e9 482 Pfam PF00881 Nitroreductase family 283 471 7.1E-17 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CIG75_RS17295 52fa36772a1b49b0ea320a241abb04e9 482 TIGRFAM TIGR03605 antibiot_sagB: SagB-type dehydrogenase domain 300 477 6.3E-45 T 28-03-2018 IPR020051 SagB-type dehydrogenase domain CIG75_RS17295 52fa36772a1b49b0ea320a241abb04e9 482 SUPERFAMILY SSF55469 279 478 1.67E-13 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CIG75_RS01680 fc9a727a7df10948bc8f38935166ac4c 647 ProSitePatterns PS00674 AAA-protein family signature. 302 320 - T 28-03-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 CIG75_RS01680 fc9a727a7df10948bc8f38935166ac4c 647 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 3 612 38.628 T 28-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 CIG75_RS01680 fc9a727a7df10948bc8f38935166ac4c 647 SMART SM00382 195 334 2.2E-24 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS01680 fc9a727a7df10948bc8f38935166ac4c 647 SUPERFAMILY SSF52540 154 403 6.46E-74 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS01680 fc9a727a7df10948bc8f38935166ac4c 647 Pfam PF06480 FtsH Extracellular 10 105 2.7E-9 T 28-03-2018 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 Reactome: R-HSA-8949664 CIG75_RS01680 fc9a727a7df10948bc8f38935166ac4c 647 Gene3D G3DSA:1.10.8.60 343 420 9.3E-22 T 28-03-2018 CIG75_RS01680 fc9a727a7df10948bc8f38935166ac4c 647 SUPERFAMILY SSF140990 413 608 3.01E-72 T 28-03-2018 CIG75_RS01680 fc9a727a7df10948bc8f38935166ac4c 647 Gene3D G3DSA:3.40.50.300 136 342 5.5E-65 T 28-03-2018 CIG75_RS01680 fc9a727a7df10948bc8f38935166ac4c 647 Pfam PF01434 Peptidase family M41 393 601 3.5E-87 T 28-03-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 CIG75_RS01680 fc9a727a7df10948bc8f38935166ac4c 647 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 199 331 2.8E-45 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CIG75_RS01680 fc9a727a7df10948bc8f38935166ac4c 647 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 111 603 4.5E-245 T 28-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 CIG75_RS06525 43f1634e290001c0927131a304c59f32 468 Gene3D G3DSA:3.40.640.10 140 349 1.2E-49 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CIG75_RS06525 43f1634e290001c0927131a304c59f32 468 Pfam PF00155 Aminotransferase class I and II 121 460 1.4E-41 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CIG75_RS06525 43f1634e290001c0927131a304c59f32 468 Gene3D G3DSA:3.90.1150.10 350 468 5.8E-24 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CIG75_RS06525 43f1634e290001c0927131a304c59f32 468 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 29 43 1.9E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CIG75_RS06525 43f1634e290001c0927131a304c59f32 468 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 43 59 1.9E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CIG75_RS06525 43f1634e290001c0927131a304c59f32 468 SUPERFAMILY SSF46785 2 78 1.3E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS06525 43f1634e290001c0927131a304c59f32 468 Gene3D G3DSA:1.10.10.10 1 71 4.5E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS06525 43f1634e290001c0927131a304c59f32 468 Pfam PF00392 Bacterial regulatory proteins, gntR family 6 69 4.1E-18 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CIG75_RS06525 43f1634e290001c0927131a304c59f32 468 SMART SM00345 10 69 5.9E-19 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CIG75_RS06525 43f1634e290001c0927131a304c59f32 468 SUPERFAMILY SSF53383 97 468 1.25E-96 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CIG75_RS03625 9725cb851a3818907e81cfcebc9730ac 247 Pfam PF00696 Amino acid kinase family 7 218 3.8E-27 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CIG75_RS03625 9725cb851a3818907e81cfcebc9730ac 247 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 6 237 1.4E-86 T 28-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 CIG75_RS03625 9725cb851a3818907e81cfcebc9730ac 247 PIRSF PIRSF005650 1 246 3.0E-77 T 28-03-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 CIG75_RS03625 9725cb851a3818907e81cfcebc9730ac 247 Gene3D G3DSA:3.40.1160.10 1 240 3.4E-36 T 28-03-2018 CIG75_RS03625 9725cb851a3818907e81cfcebc9730ac 247 SUPERFAMILY SSF53633 4 239 2.75E-60 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CIG75_RS03625 9725cb851a3818907e81cfcebc9730ac 247 Hamap MF_01220_B Uridylate kinase [pyrH]. 4 239 37.825 T 28-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 CIG75_RS10925 a62184261a45d3b5ede99df3676fdcda 325 SUPERFAMILY SSF101821 68 165 3.05E-10 T 28-03-2018 CIG75_RS10925 a62184261a45d3b5ede99df3676fdcda 325 SUPERFAMILY SSF53187 2 78 4.35E-47 T 28-03-2018 CIG75_RS10925 a62184261a45d3b5ede99df3676fdcda 325 SUPERFAMILY SSF53187 157 323 4.35E-47 T 28-03-2018 CIG75_RS10925 a62184261a45d3b5ede99df3676fdcda 325 Gene3D G3DSA:3.40.630.10 150 325 5.7E-29 T 28-03-2018 CIG75_RS10925 a62184261a45d3b5ede99df3676fdcda 325 PIRSF PIRSF001123 1 324 1.0E-68 T 28-03-2018 IPR008007 Peptidase M42 CIG75_RS10925 a62184261a45d3b5ede99df3676fdcda 325 Gene3D G3DSA:2.40.30.40 68 146 5.2E-8 T 28-03-2018 IPR023367 Peptidase M42, domain 2 CIG75_RS10925 a62184261a45d3b5ede99df3676fdcda 325 Pfam PF05343 M42 glutamyl aminopeptidase 42 315 1.1E-59 T 28-03-2018 IPR008007 Peptidase M42 CIG75_RS15655 fcd8d34c35598e4f3c51a57c2b605880 507 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 61 164 1.3E-11 T 28-03-2018 IPR000014 PAS domain CIG75_RS15655 fcd8d34c35598e4f3c51a57c2b605880 507 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 403 412 - T 28-03-2018 IPR025944 Sigma-54 interaction domain, conserved site CIG75_RS15655 fcd8d34c35598e4f3c51a57c2b605880 507 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 276 291 - T 28-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CIG75_RS15655 fcd8d34c35598e4f3c51a57c2b605880 507 Gene3D G3DSA:1.10.10.60 434 499 1.4E-12 T 28-03-2018 CIG75_RS15655 fcd8d34c35598e4f3c51a57c2b605880 507 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 213 226 - T 28-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CIG75_RS15655 fcd8d34c35598e4f3c51a57c2b605880 507 Gene3D G3DSA:3.40.50.300 167 375 5.7E-26 T 28-03-2018 CIG75_RS15655 fcd8d34c35598e4f3c51a57c2b605880 507 Pfam PF02954 Bacterial regulatory protein, Fis family 455 495 1.1E-9 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CIG75_RS15655 fcd8d34c35598e4f3c51a57c2b605880 507 SUPERFAMILY SSF52540 189 433 5.82E-67 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS15655 fcd8d34c35598e4f3c51a57c2b605880 507 Pfam PF00989 PAS fold 61 155 3.7E-11 T 28-03-2018 IPR013767 PAS fold GO:0006355 CIG75_RS15655 fcd8d34c35598e4f3c51a57c2b605880 507 SUPERFAMILY SSF55785 60 152 1.1E-16 T 28-03-2018 IPR000014 PAS domain CIG75_RS15655 fcd8d34c35598e4f3c51a57c2b605880 507 SMART SM00091 57 123 7.7E-7 T 28-03-2018 IPR000014 PAS domain CIG75_RS15655 fcd8d34c35598e4f3c51a57c2b605880 507 Gene3D G3DSA:3.30.450.20 52 166 3.7E-22 T 28-03-2018 CIG75_RS15655 fcd8d34c35598e4f3c51a57c2b605880 507 SMART SM00382 209 352 7.0E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS15655 fcd8d34c35598e4f3c51a57c2b605880 507 Pfam PF00158 Sigma-54 interaction domain 189 357 2.2E-66 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CIG75_RS15655 fcd8d34c35598e4f3c51a57c2b605880 507 SUPERFAMILY SSF46689 403 498 2.34E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CIG75_RS15655 fcd8d34c35598e4f3c51a57c2b605880 507 Gene3D G3DSA:1.10.8.60 376 433 8.0E-22 T 28-03-2018 CIG75_RS13855 d8840177ae47fa7c2c77888522914e6b 631 ProSitePatterns PS00801 Transketolase signature 1. 28 47 - T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CIG75_RS13855 d8840177ae47fa7c2c77888522914e6b 631 Gene3D G3DSA:3.40.50.920 494 626 4.8E-36 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CIG75_RS13855 d8840177ae47fa7c2c77888522914e6b 631 SUPERFAMILY SSF52922 491 624 2.49E-33 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CIG75_RS13855 d8840177ae47fa7c2c77888522914e6b 631 SUPERFAMILY SSF52518 3 191 4.75E-79 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CIG75_RS13855 d8840177ae47fa7c2c77888522914e6b 631 SUPERFAMILY SSF52518 239 379 4.75E-79 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CIG75_RS13855 d8840177ae47fa7c2c77888522914e6b 631 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 2 625 46.242 T 28-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CIG75_RS13855 d8840177ae47fa7c2c77888522914e6b 631 ProSitePatterns PS00802 Transketolase signature 2. 423 439 - T 28-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CIG75_RS13855 d8840177ae47fa7c2c77888522914e6b 631 SUPERFAMILY SSF52518 316 504 2.05E-59 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CIG75_RS13855 d8840177ae47fa7c2c77888522914e6b 631 Pfam PF02779 Transketolase, pyrimidine binding domain 317 478 2.1E-41 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CIG75_RS13855 d8840177ae47fa7c2c77888522914e6b 631 Pfam PF02780 Transketolase, C-terminal domain 494 616 1.8E-29 T 28-03-2018 IPR033248 Transketolase, C-terminal domain CIG75_RS13855 d8840177ae47fa7c2c77888522914e6b 631 Gene3D G3DSA:3.40.50.970 292 488 2.3E-60 T 28-03-2018 CIG75_RS13855 d8840177ae47fa7c2c77888522914e6b 631 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 5 623 2.9E-267 T 28-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CIG75_RS13855 d8840177ae47fa7c2c77888522914e6b 631 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 3 278 1.2E-122 T 28-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CIG75_RS13855 d8840177ae47fa7c2c77888522914e6b 631 Gene3D G3DSA:3.40.50.970 1 291 1.4E-81 T 28-03-2018 CIG75_RS13855 d8840177ae47fa7c2c77888522914e6b 631 SMART SM00861 317 482 6.7E-74 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CIG75_RS17945 5855bb209c4232c5048f035291e6ddf2 386 Pfam PF01168 Alanine racemase, N-terminal domain 13 234 4.1E-73 T 28-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CIG75_RS17945 5855bb209c4232c5048f035291e6ddf2 386 Gene3D G3DSA:3.20.20.10 3 233 3.4E-58 T 28-03-2018 IPR029066 PLP-binding barrel CIG75_RS17945 5855bb209c4232c5048f035291e6ddf2 386 SUPERFAMILY SSF51419 13 248 2.62E-69 T 28-03-2018 IPR029066 PLP-binding barrel CIG75_RS17945 5855bb209c4232c5048f035291e6ddf2 386 Pfam PF00842 Alanine racemase, C-terminal domain 248 373 4.7E-47 T 28-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CIG75_RS17945 5855bb209c4232c5048f035291e6ddf2 386 SUPERFAMILY SSF50621 240 376 2.62E-52 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CIG75_RS17945 5855bb209c4232c5048f035291e6ddf2 386 Hamap MF_01201 Alanine racemase. 6 375 36.023 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CIG75_RS17945 5855bb209c4232c5048f035291e6ddf2 386 PRINTS PR00992 Alanine racemase signature 280 295 7.3E-64 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CIG75_RS17945 5855bb209c4232c5048f035291e6ddf2 386 PRINTS PR00992 Alanine racemase signature 68 86 7.3E-64 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CIG75_RS17945 5855bb209c4232c5048f035291e6ddf2 386 PRINTS PR00992 Alanine racemase signature 301 318 7.3E-64 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CIG75_RS17945 5855bb209c4232c5048f035291e6ddf2 386 PRINTS PR00992 Alanine racemase signature 207 234 7.3E-64 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CIG75_RS17945 5855bb209c4232c5048f035291e6ddf2 386 PRINTS PR00992 Alanine racemase signature 263 278 7.3E-64 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CIG75_RS17945 5855bb209c4232c5048f035291e6ddf2 386 PRINTS PR00992 Alanine racemase signature 32 48 7.3E-64 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CIG75_RS17945 5855bb209c4232c5048f035291e6ddf2 386 PRINTS PR00992 Alanine racemase signature 129 141 7.3E-64 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CIG75_RS17945 5855bb209c4232c5048f035291e6ddf2 386 PRINTS PR00992 Alanine racemase signature 357 370 7.3E-64 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CIG75_RS17945 5855bb209c4232c5048f035291e6ddf2 386 PRINTS PR00992 Alanine racemase signature 164 175 7.3E-64 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CIG75_RS17945 5855bb209c4232c5048f035291e6ddf2 386 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 37 47 - T 28-03-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CIG75_RS17945 5855bb209c4232c5048f035291e6ddf2 386 Gene3D G3DSA:2.40.37.10 234 384 5.6E-63 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CIG75_RS17945 5855bb209c4232c5048f035291e6ddf2 386 SMART SM01005 247 375 1.9E-71 T 28-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CIG75_RS17945 5855bb209c4232c5048f035291e6ddf2 386 TIGRFAM TIGR00492 alr: alanine racemase 7 374 1.4E-123 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CIG75_RS10225 1a2a050d8c7f6f17a8aaa68d05a5034c 286 SUPERFAMILY SSF161098 47 272 5.36E-62 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CIG75_RS10225 1a2a050d8c7f6f17a8aaa68d05a5034c 286 Gene3D G3DSA:1.20.58.370 2 38 8.9E-6 T 28-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain CIG75_RS10225 1a2a050d8c7f6f17a8aaa68d05a5034c 286 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 277 1.0E-13 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CIG75_RS10225 1a2a050d8c7f6f17a8aaa68d05a5034c 286 Gene3D G3DSA:1.10.3720.10 52 284 7.6E-45 T 28-03-2018 CIG75_RS16945 1704be811c0dba241db4bb31bdca8605 317 Pfam PF01903 CbiX 12 117 9.1E-26 T 28-03-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 CIG75_RS16945 1704be811c0dba241db4bb31bdca8605 317 Pfam PF01903 CbiX 143 247 3.5E-24 T 28-03-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 CIG75_RS16945 1704be811c0dba241db4bb31bdca8605 317 Gene3D G3DSA:3.40.50.1400 1 111 7.5E-27 T 28-03-2018 CIG75_RS16945 1704be811c0dba241db4bb31bdca8605 317 Gene3D G3DSA:3.40.50.1400 113 240 4.8E-26 T 28-03-2018 CIG75_RS16945 1704be811c0dba241db4bb31bdca8605 317 SUPERFAMILY SSF53800 4 253 3.05E-53 T 28-03-2018 CIG75_RS10830 81d88c310afe93b597bda4b50fd11ec6 320 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 9 292 1.5E-103 T 28-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 CIG75_RS10830 81d88c310afe93b597bda4b50fd11ec6 320 SUPERFAMILY SSF52540 158 269 2.28E-10 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS10830 81d88c310afe93b597bda4b50fd11ec6 320 SUPERFAMILY SSF52540 5 79 2.28E-10 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS10830 81d88c310afe93b597bda4b50fd11ec6 320 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 8 317 29.553 T 28-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 CIG75_RS10830 81d88c310afe93b597bda4b50fd11ec6 320 Gene3D G3DSA:1.10.287.890 203 284 1.7E-28 T 28-03-2018 CIG75_RS10830 81d88c310afe93b597bda4b50fd11ec6 320 Pfam PF01715 IPP transferase 41 288 2.0E-82 T 28-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 CIG75_RS10830 81d88c310afe93b597bda4b50fd11ec6 320 Gene3D G3DSA:3.40.50.300 4 200 4.2E-65 T 28-03-2018 CIG75_RS10830 81d88c310afe93b597bda4b50fd11ec6 320 SUPERFAMILY SSF52540 8 164 3.99E-17 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS15675 0d3be140032d1a855bef4f2a90d7ea62 362 SUPERFAMILY SSF47807 179 269 1.03E-11 T 28-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 CIG75_RS15675 0d3be140032d1a855bef4f2a90d7ea62 362 Gene3D G3DSA:1.10.150.20 193 269 2.3E-12 T 28-03-2018 CIG75_RS15675 0d3be140032d1a855bef4f2a90d7ea62 362 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 3 169 3.4E-31 T 28-03-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 CIG75_RS15675 0d3be140032d1a855bef4f2a90d7ea62 362 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 179 268 1.6E-12 T 28-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 CIG75_RS15675 0d3be140032d1a855bef4f2a90d7ea62 362 Gene3D G3DSA:3.40.50.1010 1 192 5.4E-44 T 28-03-2018 IPR029060 PIN domain-like CIG75_RS15675 0d3be140032d1a855bef4f2a90d7ea62 362 SUPERFAMILY SSF88723 3 173 2.71E-29 T 28-03-2018 IPR029060 PIN domain-like CIG75_RS15675 0d3be140032d1a855bef4f2a90d7ea62 362 SMART SM00475 1 268 5.1E-27 T 28-03-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 CIG75_RS00430 b0af76fb9bff3dfdb5b7f64718659662 232 Pfam PF00072 Response regulator receiver domain 6 114 1.4E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CIG75_RS00430 b0af76fb9bff3dfdb5b7f64718659662 232 SMART SM00448 4 114 2.5E-37 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CIG75_RS00430 b0af76fb9bff3dfdb5b7f64718659662 232 Pfam PF00486 Transcriptional regulatory protein, C terminal 153 227 4.0E-22 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CIG75_RS00430 b0af76fb9bff3dfdb5b7f64718659662 232 SMART SM00862 153 227 3.5E-25 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CIG75_RS00430 b0af76fb9bff3dfdb5b7f64718659662 232 Gene3D G3DSA:1.10.10.10 129 231 1.1E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS00430 b0af76fb9bff3dfdb5b7f64718659662 232 Gene3D G3DSA:3.40.50.2300 2 128 1.1E-33 T 28-03-2018 CIG75_RS00430 b0af76fb9bff3dfdb5b7f64718659662 232 SUPERFAMILY SSF52172 1 180 4.83E-37 T 28-03-2018 IPR011006 CheY-like superfamily CIG75_RS05185 c6f7b3d8413dad86f7fc9b3196db8f94 1987 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1204 1235 7.0E-4 T 28-03-2018 IPR006530 YD repeat CIG75_RS05185 c6f7b3d8413dad86f7fc9b3196db8f94 1987 Pfam PF12256 Insecticide toxin TcdB middle/N-terminal region 645 716 2.6E-8 T 28-03-2018 IPR022045 Insecticide toxin TcdB middle/N-terminal CIG75_RS05185 c6f7b3d8413dad86f7fc9b3196db8f94 1987 Pfam PF12256 Insecticide toxin TcdB middle/N-terminal region 756 821 1.5E-7 T 28-03-2018 IPR022045 Insecticide toxin TcdB middle/N-terminal CIG75_RS05185 c6f7b3d8413dad86f7fc9b3196db8f94 1987 Gene3D G3DSA:2.130.10.130 566 739 1.4E-6 T 28-03-2018 CIG75_RS05185 c6f7b3d8413dad86f7fc9b3196db8f94 1987 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1668 1749 2.8E-24 T 28-03-2018 IPR022385 Rhs repeat-associated core GO:0097264 CIG75_RS05185 c6f7b3d8413dad86f7fc9b3196db8f94 1987 Pfam PF03534 Salmonella virulence plasmid 65kDa B protein 18 197 3.7E-13 T 28-03-2018 IPR003284 Salmonella virulence plasmid 65kDa B protein GO:0005737 CIG75_RS05185 c6f7b3d8413dad86f7fc9b3196db8f94 1987 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 488 553 1.0E-6 T 28-03-2018 CIG75_RS05185 c6f7b3d8413dad86f7fc9b3196db8f94 1987 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 320 385 1.3E-6 T 28-03-2018 CIG75_RS05185 c6f7b3d8413dad86f7fc9b3196db8f94 1987 SUPERFAMILY SSF69318 308 666 4.05E-33 T 28-03-2018 CIG75_RS05185 c6f7b3d8413dad86f7fc9b3196db8f94 1987 Gene3D G3DSA:2.130.10.130 409 565 2.1E-14 T 28-03-2018 CIG75_RS05185 c6f7b3d8413dad86f7fc9b3196db8f94 1987 Gene3D G3DSA:2.130.10.130 180 408 1.2E-9 T 28-03-2018 CIG75_RS08700 5273e5dd33f13b930646845bcb562024 145 Pfam PF13581 Histidine kinase-like ATPase domain 10 135 2.0E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS08700 5273e5dd33f13b930646845bcb562024 145 SMART SM00387 35 139 9.7E-10 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS08700 5273e5dd33f13b930646845bcb562024 145 Gene3D G3DSA:3.30.565.10 1 142 2.4E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS08700 5273e5dd33f13b930646845bcb562024 145 TIGRFAM TIGR01925 spIIAB: anti-sigma F factor 1 136 2.4E-66 T 28-03-2018 IPR010194 Anti-sigma F factor GO:0004674|GO:0005524|GO:0006468|GO:0016989|GO:0030435|GO:0045892 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 CIG75_RS08700 5273e5dd33f13b930646845bcb562024 145 SUPERFAMILY SSF55874 29 133 2.75E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS08700 5273e5dd33f13b930646845bcb562024 145 Hamap MF_00637 Anti-sigma F factor [spoIIAB]. 1 139 35.133 T 28-03-2018 IPR010194 Anti-sigma F factor GO:0004674|GO:0005524|GO:0006468|GO:0016989|GO:0030435|GO:0045892 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 CIG75_RS03000 130c38dbfb96b92a7c352a1d70bfa91d 215 Pfam PF00005 ABC transporter 21 165 1.8E-36 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS03000 130c38dbfb96b92a7c352a1d70bfa91d 215 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS03000 130c38dbfb96b92a7c352a1d70bfa91d 215 Gene3D G3DSA:3.40.50.300 1 215 2.6E-67 T 28-03-2018 CIG75_RS03000 130c38dbfb96b92a7c352a1d70bfa91d 215 SUPERFAMILY SSF52540 3 213 2.59E-72 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS03000 130c38dbfb96b92a7c352a1d70bfa91d 215 SMART SM00382 30 214 1.9E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS09775 88240f976e1998922f0467f38e0932f5 3491 Gene3D G3DSA:2.30.38.10 2935 3013 3.0E-23 T 28-03-2018 CIG75_RS09775 88240f976e1998922f0467f38e0932f5 3491 ProSitePatterns PS00455 Putative AMP-binding domain signature. 629 640 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS09775 88240f976e1998922f0467f38e0932f5 3491 SUPERFAMILY SSF53474 3193 3483 3.89E-63 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS09775 88240f976e1998922f0467f38e0932f5 3491 SUPERFAMILY SSF47336 985 1058 3.8E-20 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS09775 88240f976e1998922f0467f38e0932f5 3491 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1580 1988 9.1E-134 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS09775 88240f976e1998922f0467f38e0932f5 3491 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2648 3044 1.1E-129 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS09775 88240f976e1998922f0467f38e0932f5 3491 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 508 908 2.7E-137 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS09775 88240f976e1998922f0467f38e0932f5 3491 SMART SM00824 Thioesterase 3224 3483 4.9E-4 T 28-03-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 CIG75_RS09775 88240f976e1998922f0467f38e0932f5 3491 Gene3D G3DSA:1.10.1200.10 3136 3202 6.7E-18 T 28-03-2018 CIG75_RS09775 88240f976e1998922f0467f38e0932f5 3491 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1701 1712 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS09775 88240f976e1998922f0467f38e0932f5 3491 SUPERFAMILY SSF52777 2349 2591 1.33E-70 T 28-03-2018 CIG75_RS09775 88240f976e1998922f0467f38e0932f5 3491 SUPERFAMILY SSF56801 444 1006 1.7E-165 T 28-03-2018 CIG75_RS09775 88240f976e1998922f0467f38e0932f5 3491 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2101 2116 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS09775 88240f976e1998922f0467f38e0932f5 3491 SMART SM00823 Phosphopantetheine attachment site 3130 3198 0.008 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS09775 88240f976e1998922f0467f38e0932f5 3491 SMART SM00823 Phosphopantetheine attachment site 2077 2146 1.9E-6 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS09775 88240f976e1998922f0467f38e0932f5 3491 SMART SM00823 Phosphopantetheine attachment site 993 1062 1.0E-4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS09775 88240f976e1998922f0467f38e0932f5 3491 Gene3D G3DSA:3.30.559.10 1092 1295 6.8E-48 T 28-03-2018 CIG75_RS09775 88240f976e1998922f0467f38e0932f5 3491 Gene3D G3DSA:3.30.559.10 2144 2368 4.9E-52 T 28-03-2018 CIG75_RS09775 88240f976e1998922f0467f38e0932f5 3491 Gene3D G3DSA:3.30.559.10 12 224 1.5E-47 T 28-03-2018 CIG75_RS09775 88240f976e1998922f0467f38e0932f5 3491 SUPERFAMILY SSF56801 2586 3143 1.44E-159 T 28-03-2018 CIG75_RS09775 88240f976e1998922f0467f38e0932f5 3491 Gene3D G3DSA:2.30.38.10 793 874 4.1E-25 T 28-03-2018 CIG75_RS09775 88240f976e1998922f0467f38e0932f5 3491 Gene3D G3DSA:2.30.38.10 1873 1954 2.1E-24 T 28-03-2018 CIG75_RS09775 88240f976e1998922f0467f38e0932f5 3491 SUPERFAMILY SSF52777 1098 1274 1.08E-51 T 28-03-2018 CIG75_RS09775 88240f976e1998922f0467f38e0932f5 3491 SUPERFAMILY SSF52777 26 202 3.56E-54 T 28-03-2018 CIG75_RS09775 88240f976e1998922f0467f38e0932f5 3491 Gene3D G3DSA:3.40.50.980 1708 1869 3.2E-30 T 28-03-2018 CIG75_RS09775 88240f976e1998922f0467f38e0932f5 3491 Gene3D G3DSA:3.40.50.980 2774 2934 1.7E-34 T 28-03-2018 CIG75_RS09775 88240f976e1998922f0467f38e0932f5 3491 Gene3D G3DSA:3.40.50.980 635 792 2.6E-30 T 28-03-2018 CIG75_RS09775 88240f976e1998922f0467f38e0932f5 3491 SUPERFAMILY SSF52777 208 472 1.22E-68 T 28-03-2018 CIG75_RS09775 88240f976e1998922f0467f38e0932f5 3491 Gene3D G3DSA:1.10.1200.10 997 1070 3.1E-23 T 28-03-2018 CIG75_RS09775 88240f976e1998922f0467f38e0932f5 3491 Gene3D G3DSA:3.30.300.30 1959 2082 1.5E-39 T 28-03-2018 CIG75_RS09775 88240f976e1998922f0467f38e0932f5 3491 Gene3D G3DSA:3.30.300.30 879 996 4.3E-42 T 28-03-2018 CIG75_RS09775 88240f976e1998922f0467f38e0932f5 3491 Gene3D G3DSA:3.30.300.30 3015 3135 5.0E-41 T 28-03-2018 CIG75_RS09775 88240f976e1998922f0467f38e0932f5 3491 SUPERFAMILY SSF47336 3123 3194 7.07E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS09775 88240f976e1998922f0467f38e0932f5 3491 SUPERFAMILY SSF47336 2069 2142 4.32E-21 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS09775 88240f976e1998922f0467f38e0932f5 3491 SUPERFAMILY SSF52777 1282 1526 5.23E-65 T 28-03-2018 CIG75_RS09775 88240f976e1998922f0467f38e0932f5 3491 Pfam PF00550 Phosphopantetheine attachment site 3132 3191 9.2E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS09775 88240f976e1998922f0467f38e0932f5 3491 Pfam PF00550 Phosphopantetheine attachment site 2081 2141 2.1E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS09775 88240f976e1998922f0467f38e0932f5 3491 Pfam PF00550 Phosphopantetheine attachment site 994 1057 6.3E-16 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS09775 88240f976e1998922f0467f38e0932f5 3491 Gene3D G3DSA:3.40.50.1820 3203 3484 4.6E-26 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS09775 88240f976e1998922f0467f38e0932f5 3491 Pfam PF00501 AMP-binding enzyme 2628 3020 2.8E-99 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS09775 88240f976e1998922f0467f38e0932f5 3491 Pfam PF00501 AMP-binding enzyme 1559 1964 8.9E-100 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS09775 88240f976e1998922f0467f38e0932f5 3491 Pfam PF00501 AMP-binding enzyme 487 884 3.8E-101 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS09775 88240f976e1998922f0467f38e0932f5 3491 SUPERFAMILY SSF52777 2160 2362 3.45E-50 T 28-03-2018 CIG75_RS09775 88240f976e1998922f0467f38e0932f5 3491 Gene3D G3DSA:3.40.50.980 2618 2773 9.3E-48 T 28-03-2018 CIG75_RS09775 88240f976e1998922f0467f38e0932f5 3491 Gene3D G3DSA:3.40.50.980 478 634 2.7E-51 T 28-03-2018 CIG75_RS09775 88240f976e1998922f0467f38e0932f5 3491 Gene3D G3DSA:3.40.50.980 1550 1707 4.8E-52 T 28-03-2018 CIG75_RS09775 88240f976e1998922f0467f38e0932f5 3491 Pfam PF00668 Condensation domain 23 465 1.3E-120 T 28-03-2018 IPR001242 Condensation domain CIG75_RS09775 88240f976e1998922f0467f38e0932f5 3491 Pfam PF00668 Condensation domain 2163 2607 2.5E-121 T 28-03-2018 IPR001242 Condensation domain CIG75_RS09775 88240f976e1998922f0467f38e0932f5 3491 Pfam PF00668 Condensation domain 1094 1537 1.5E-121 T 28-03-2018 IPR001242 Condensation domain CIG75_RS09775 88240f976e1998922f0467f38e0932f5 3491 SUPERFAMILY SSF56801 1519 2090 5.76E-159 T 28-03-2018 CIG75_RS09775 88240f976e1998922f0467f38e0932f5 3491 Pfam PF13193 AMP-binding enzyme C-terminal domain 892 966 9.6E-15 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS09775 88240f976e1998922f0467f38e0932f5 3491 Pfam PF13193 AMP-binding enzyme C-terminal domain 3028 3102 2.8E-16 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS09775 88240f976e1998922f0467f38e0932f5 3491 Pfam PF13193 AMP-binding enzyme C-terminal domain 1972 2049 3.4E-12 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS09775 88240f976e1998922f0467f38e0932f5 3491 Gene3D G3DSA:1.10.1200.10 2083 2143 5.7E-24 T 28-03-2018 CIG75_RS09775 88240f976e1998922f0467f38e0932f5 3491 Pfam PF00975 Thioesterase domain 3217 3479 1.5E-36 T 28-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CIG75_RS09775 88240f976e1998922f0467f38e0932f5 3491 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2768 2779 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS19830 19280bc329d8dd6d5afe788f2018f13b 123 Gene3D G3DSA:1.10.1520.10 3 123 7.1E-18 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CIG75_RS19830 19280bc329d8dd6d5afe788f2018f13b 123 PIRSF PIRSF005520 1 123 8.0E-48 T 28-03-2018 IPR008226 Mini-ribonuclease 3 family CIG75_RS19830 19280bc329d8dd6d5afe788f2018f13b 123 SUPERFAMILY SSF69065 2 118 2.62E-37 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CIG75_RS19830 19280bc329d8dd6d5afe788f2018f13b 123 Hamap MF_01468 Mini-ribonuclease 3 [mrnC]. 1 119 27.937 T 28-03-2018 IPR008226 Mini-ribonuclease 3 family CIG75_RS19830 19280bc329d8dd6d5afe788f2018f13b 123 Pfam PF00636 Ribonuclease III domain 5 100 1.3E-16 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CIG75_RS11870 5580347bcc74f48fab22caf25d84a466 270 Pfam PF01148 Cytidylyltransferase family 4 266 2.2E-65 T 28-03-2018 CIG75_RS11870 5580347bcc74f48fab22caf25d84a466 270 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 226 252 - T 28-03-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 CIG75_RS10730 e1e034b9e0d76597bf36d066829b380c 369 SUPERFAMILY SSF52402 8 244 2.65E-60 T 28-03-2018 CIG75_RS10730 e1e034b9e0d76597bf36d066829b380c 369 Gene3D G3DSA:2.30.30.280 214 277 2.5E-26 T 28-03-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 Reactome: R-HSA-6787450 CIG75_RS10730 e1e034b9e0d76597bf36d066829b380c 369 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 8 357 41.067 T 28-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 CIG75_RS10730 e1e034b9e0d76597bf36d066829b380c 369 Gene3D G3DSA:3.40.50.620 1 213 6.2E-72 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CIG75_RS10730 e1e034b9e0d76597bf36d066829b380c 369 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 9 356 2.5E-139 T 28-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 CIG75_RS10730 e1e034b9e0d76597bf36d066829b380c 369 Pfam PF03054 tRNA methyl transferase 9 356 4.7E-145 T 28-03-2018 CIG75_RS10730 e1e034b9e0d76597bf36d066829b380c 369 Gene3D G3DSA:2.40.30.10 278 369 1.8E-26 T 28-03-2018 CIG75_RS09155 b17bb21c858c25802d749d98ebcfb299 564 Gene3D G3DSA:1.10.287.950 514 564 1.2E-7 T 28-03-2018 CIG75_RS09155 b17bb21c858c25802d749d98ebcfb299 564 Gene3D G3DSA:1.10.287.950 51 316 9.3E-7 T 28-03-2018 CIG75_RS09155 b17bb21c858c25802d749d98ebcfb299 564 Pfam PF00672 HAMP domain 206 255 4.9E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CIG75_RS09155 b17bb21c858c25802d749d98ebcfb299 564 SMART SM00304 206 259 1.9E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CIG75_RS09155 b17bb21c858c25802d749d98ebcfb299 564 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 386 413 4.2E-20 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CIG75_RS09155 b17bb21c858c25802d749d98ebcfb299 564 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 7 32 4.2E-20 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CIG75_RS09155 b17bb21c858c25802d749d98ebcfb299 564 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 415 444 4.2E-20 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CIG75_RS09155 b17bb21c858c25802d749d98ebcfb299 564 SMART SM00283 288 563 8.8E-91 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CIG75_RS09155 b17bb21c858c25802d749d98ebcfb299 564 SUPERFAMILY SSF58104 294 563 2.35E-76 T 28-03-2018 CIG75_RS09155 b17bb21c858c25802d749d98ebcfb299 564 SUPERFAMILY SSF58104 231 261 2.35E-76 T 28-03-2018 CIG75_RS09155 b17bb21c858c25802d749d98ebcfb299 564 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 333 516 1.7E-51 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CIG75_RS09155 b17bb21c858c25802d749d98ebcfb299 564 Gene3D G3DSA:1.10.287.950 317 513 4.9E-56 T 28-03-2018 CIG75_RS07675 a34d5a7bb5cc0ad7eace3e73169f15b9 575 ProSitePatterns PS00455 Putative AMP-binding domain signature. 214 225 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS07675 a34d5a7bb5cc0ad7eace3e73169f15b9 575 Gene3D G3DSA:3.30.300.30 461 572 2.1E-28 T 28-03-2018 CIG75_RS07675 a34d5a7bb5cc0ad7eace3e73169f15b9 575 Gene3D G3DSA:2.30.38.10 374 458 1.9E-21 T 28-03-2018 CIG75_RS07675 a34d5a7bb5cc0ad7eace3e73169f15b9 575 SUPERFAMILY SSF56801 11 565 1.31E-164 T 28-03-2018 CIG75_RS07675 a34d5a7bb5cc0ad7eace3e73169f15b9 575 Gene3D G3DSA:3.40.50.980 44 219 7.9E-42 T 28-03-2018 CIG75_RS07675 a34d5a7bb5cc0ad7eace3e73169f15b9 575 Pfam PF00501 AMP-binding enzyme 59 465 6.5E-94 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS07675 a34d5a7bb5cc0ad7eace3e73169f15b9 575 Gene3D G3DSA:3.40.50.980 220 373 2.0E-41 T 28-03-2018 CIG75_RS07675 a34d5a7bb5cc0ad7eace3e73169f15b9 575 Pfam PF13193 AMP-binding enzyme C-terminal domain 474 552 9.5E-25 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS16145 be76d9ce36d7cf9fae501dbcd17a7024 590 SUPERFAMILY SSF56645 24 262 2.23E-68 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CIG75_RS16145 be76d9ce36d7cf9fae501dbcd17a7024 590 SUPERFAMILY SSF47203 478 543 1.61E-5 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CIG75_RS16145 be76d9ce36d7cf9fae501dbcd17a7024 590 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 30 141 9.4E-24 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CIG75_RS16145 be76d9ce36d7cf9fae501dbcd17a7024 590 SUPERFAMILY SSF47203 249 416 2.74E-46 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CIG75_RS16145 be76d9ce36d7cf9fae501dbcd17a7024 590 Gene3D G3DSA:1.20.140.10 240 420 1.1E-51 T 28-03-2018 CIG75_RS16145 be76d9ce36d7cf9fae501dbcd17a7024 590 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 146 239 2.9E-21 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CIG75_RS16145 be76d9ce36d7cf9fae501dbcd17a7024 590 Gene3D G3DSA:1.20.140.10 421 590 3.6E-15 T 28-03-2018 CIG75_RS16145 be76d9ce36d7cf9fae501dbcd17a7024 590 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 479 544 2.3E-4 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CIG75_RS16145 be76d9ce36d7cf9fae501dbcd17a7024 590 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 251 410 1.3E-36 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CIG75_RS16145 be76d9ce36d7cf9fae501dbcd17a7024 590 Gene3D G3DSA:1.10.540.10 2 144 3.1E-28 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CIG75_RS16145 be76d9ce36d7cf9fae501dbcd17a7024 590 Gene3D G3DSA:2.40.110.10 145 239 3.6E-32 T 28-03-2018 CIG75_RS16145 be76d9ce36d7cf9fae501dbcd17a7024 590 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 148 160 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CIG75_RS20320 216365bd5ea81094c393f7b9970a2c7e 282 Pfam PF00288 GHMP kinases N terminal domain 85 143 1.6E-12 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 CIG75_RS20320 216365bd5ea81094c393f7b9970a2c7e 282 SUPERFAMILY SSF55060 162 280 2.88E-32 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CIG75_RS20320 216365bd5ea81094c393f7b9970a2c7e 282 PIRSF PIRSF010376 1 281 1.4E-97 T 28-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 CIG75_RS20320 216365bd5ea81094c393f7b9970a2c7e 282 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 2 279 36.533 T 28-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 CIG75_RS20320 216365bd5ea81094c393f7b9970a2c7e 282 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 3 279 2.8E-93 T 28-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 CIG75_RS20320 216365bd5ea81094c393f7b9970a2c7e 282 Pfam PF08544 GHMP kinases C terminal 197 270 3.7E-14 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CIG75_RS20320 216365bd5ea81094c393f7b9970a2c7e 282 Gene3D G3DSA:3.30.230.10 2 158 7.6E-51 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CIG75_RS20320 216365bd5ea81094c393f7b9970a2c7e 282 Gene3D G3DSA:3.30.70.890 160 276 3.1E-31 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CIG75_RS20320 216365bd5ea81094c393f7b9970a2c7e 282 SUPERFAMILY SSF54211 2 156 1.37E-47 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CIG75_RS11930 c4e4de0b14b0b6b711d41eb1276fd698 159 Hamap MF_01440 Chemoreceptor glutamine deamidase CheD [cheD]. 3 155 25.73 T 28-03-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 CIG75_RS11930 c4e4de0b14b0b6b711d41eb1276fd698 159 Pfam PF03975 CheD chemotactic sensory transduction 47 151 2.7E-33 T 28-03-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 CIG75_RS11930 c4e4de0b14b0b6b711d41eb1276fd698 159 SUPERFAMILY SSF64438 3 157 1.1E-45 T 28-03-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic CIG75_RS10455 ea4517e20d51597a47473d5816569617 452 SUPERFAMILY SSF51971 130 375 4.65E-60 T 28-03-2018 CIG75_RS10455 ea4517e20d51597a47473d5816569617 452 PRINTS PR00419 Adrenodoxin reductase family signature 132 154 8.4E-19 T 28-03-2018 CIG75_RS10455 ea4517e20d51597a47473d5816569617 452 PRINTS PR00419 Adrenodoxin reductase family signature 155 168 8.4E-19 T 28-03-2018 CIG75_RS10455 ea4517e20d51597a47473d5816569617 452 PRINTS PR00419 Adrenodoxin reductase family signature 265 279 8.4E-19 T 28-03-2018 CIG75_RS10455 ea4517e20d51597a47473d5816569617 452 PRINTS PR00419 Adrenodoxin reductase family signature 197 207 8.4E-19 T 28-03-2018 CIG75_RS10455 ea4517e20d51597a47473d5816569617 452 Gene3D G3DSA:3.50.50.60 279 452 8.7E-23 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS10455 ea4517e20d51597a47473d5816569617 452 SUPERFAMILY SSF46548 8 141 5.75E-29 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CIG75_RS10455 ea4517e20d51597a47473d5816569617 452 Gene3D G3DSA:3.40.50.720 124 223 2.1E-20 T 28-03-2018 CIG75_RS10455 ea4517e20d51597a47473d5816569617 452 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 11 119 1.3E-36 T 28-03-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 CIG75_RS10455 ea4517e20d51597a47473d5816569617 452 Gene3D G3DSA:1.10.1060.10 2 123 4.6E-33 T 28-03-2018 CIG75_RS10455 ea4517e20d51597a47473d5816569617 452 Gene3D G3DSA:3.50.50.60 224 278 3.7E-17 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS10455 ea4517e20d51597a47473d5816569617 452 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 132 432 7.6E-30 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS06675 58d8f574dfa1450db5a75ec458fa2342 624 SUPERFAMILY SSF52540 353 599 2.66E-72 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS06675 58d8f574dfa1450db5a75ec458fa2342 624 Gene3D G3DSA:1.20.1560.10 16 343 7.5E-21 T 28-03-2018 CIG75_RS06675 58d8f574dfa1450db5a75ec458fa2342 624 SUPERFAMILY SSF90123 505 514 4.58E-24 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CIG75_RS06675 58d8f574dfa1450db5a75ec458fa2342 624 SUPERFAMILY SSF90123 22 321 4.58E-24 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CIG75_RS06675 58d8f574dfa1450db5a75ec458fa2342 624 Gene3D G3DSA:3.40.50.300 344 604 2.2E-68 T 28-03-2018 CIG75_RS06675 58d8f574dfa1450db5a75ec458fa2342 624 SMART SM00382 384 575 2.6E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS06675 58d8f574dfa1450db5a75ec458fa2342 624 Pfam PF00005 ABC transporter 375 528 2.5E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS06675 58d8f574dfa1450db5a75ec458fa2342 624 ProSitePatterns PS00211 ABC transporters family signature. 501 515 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS19960 2bf88f488373ddb23599f1df8d1280cc 299 Pfam PF00005 ABC transporter 27 164 2.1E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS19960 2bf88f488373ddb23599f1df8d1280cc 299 SMART SM00382 34 213 2.0E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS19960 2bf88f488373ddb23599f1df8d1280cc 299 SUPERFAMILY SSF52540 10 235 7.89E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS19960 2bf88f488373ddb23599f1df8d1280cc 299 Gene3D G3DSA:3.40.50.300 2 241 5.1E-45 T 28-03-2018 CIG75_RS10575 6942c055bb4d6eb2eb2e0612fffcf31b 2406 SUPERFAMILY SSF52777 1098 1299 4.17E-36 T 28-03-2018 CIG75_RS10575 6942c055bb4d6eb2eb2e0612fffcf31b 2406 Gene3D G3DSA:3.30.559.10 16 223 7.2E-44 T 28-03-2018 CIG75_RS10575 6942c055bb4d6eb2eb2e0612fffcf31b 2406 ProSitePatterns PS00455 Putative AMP-binding domain signature. 629 640 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS10575 6942c055bb4d6eb2eb2e0612fffcf31b 2406 Gene3D G3DSA:3.40.50.980 481 633 9.6E-49 T 28-03-2018 CIG75_RS10575 6942c055bb4d6eb2eb2e0612fffcf31b 2406 Pfam PF00975 Thioesterase domain 2154 2397 7.7E-37 T 28-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CIG75_RS10575 6942c055bb4d6eb2eb2e0612fffcf31b 2406 Pfam PF00501 AMP-binding enzyme 488 893 1.7E-104 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS10575 6942c055bb4d6eb2eb2e0612fffcf31b 2406 Pfam PF00501 AMP-binding enzyme 1558 1957 5.7E-102 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS10575 6942c055bb4d6eb2eb2e0612fffcf31b 2406 Gene3D G3DSA:2.30.38.10 804 886 7.5E-23 T 28-03-2018 CIG75_RS10575 6942c055bb4d6eb2eb2e0612fffcf31b 2406 Gene3D G3DSA:3.30.300.30 888 1008 1.7E-39 T 28-03-2018 CIG75_RS10575 6942c055bb4d6eb2eb2e0612fffcf31b 2406 Gene3D G3DSA:3.30.300.30 1952 2070 1.6E-29 T 28-03-2018 CIG75_RS10575 6942c055bb4d6eb2eb2e0612fffcf31b 2406 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2089 2104 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS10575 6942c055bb4d6eb2eb2e0612fffcf31b 2406 Gene3D G3DSA:2.30.38.10 1858 1949 3.1E-23 T 28-03-2018 CIG75_RS10575 6942c055bb4d6eb2eb2e0612fffcf31b 2406 Gene3D G3DSA:1.10.1200.10 2071 2137 7.9E-23 T 28-03-2018 CIG75_RS10575 6942c055bb4d6eb2eb2e0612fffcf31b 2406 Pfam PF13193 AMP-binding enzyme C-terminal domain 1965 2036 8.8E-7 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS10575 6942c055bb4d6eb2eb2e0612fffcf31b 2406 Pfam PF13193 AMP-binding enzyme C-terminal domain 901 977 4.8E-14 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS10575 6942c055bb4d6eb2eb2e0612fffcf31b 2406 Gene3D G3DSA:1.10.1200.10 1009 1081 8.5E-21 T 28-03-2018 CIG75_RS10575 6942c055bb4d6eb2eb2e0612fffcf31b 2406 SUPERFAMILY SSF52777 25 201 2.22E-50 T 28-03-2018 CIG75_RS10575 6942c055bb4d6eb2eb2e0612fffcf31b 2406 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1702 1713 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS10575 6942c055bb4d6eb2eb2e0612fffcf31b 2406 SMART SM00823 Phosphopantetheine attachment site 2065 2134 4.4E-7 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS10575 6942c055bb4d6eb2eb2e0612fffcf31b 2406 SMART SM00823 Phosphopantetheine attachment site 1005 1073 0.16 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS10575 6942c055bb4d6eb2eb2e0612fffcf31b 2406 Gene3D G3DSA:3.40.50.980 1708 1857 4.2E-41 T 28-03-2018 CIG75_RS10575 6942c055bb4d6eb2eb2e0612fffcf31b 2406 Gene3D G3DSA:3.40.50.980 634 798 1.6E-39 T 28-03-2018 CIG75_RS10575 6942c055bb4d6eb2eb2e0612fffcf31b 2406 SUPERFAMILY SSF52777 1287 1523 8.0E-40 T 28-03-2018 CIG75_RS10575 6942c055bb4d6eb2eb2e0612fffcf31b 2406 Gene3D G3DSA:3.40.50.980 1550 1707 1.1E-48 T 28-03-2018 CIG75_RS10575 6942c055bb4d6eb2eb2e0612fffcf31b 2406 SUPERFAMILY SSF56801 447 1018 1.1E-165 T 28-03-2018 CIG75_RS10575 6942c055bb4d6eb2eb2e0612fffcf31b 2406 SUPERFAMILY SSF52777 208 457 4.67E-56 T 28-03-2018 CIG75_RS10575 6942c055bb4d6eb2eb2e0612fffcf31b 2406 Pfam PF00668 Condensation domain 1099 1539 1.6E-72 T 28-03-2018 IPR001242 Condensation domain CIG75_RS10575 6942c055bb4d6eb2eb2e0612fffcf31b 2406 Pfam PF00668 Condensation domain 22 465 1.1E-102 T 28-03-2018 IPR001242 Condensation domain CIG75_RS10575 6942c055bb4d6eb2eb2e0612fffcf31b 2406 SUPERFAMILY SSF47336 2059 2131 3.53E-19 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10575 6942c055bb4d6eb2eb2e0612fffcf31b 2406 Gene3D G3DSA:3.30.559.10 1091 1294 3.1E-29 T 28-03-2018 CIG75_RS10575 6942c055bb4d6eb2eb2e0612fffcf31b 2406 SUPERFAMILY SSF47336 997 1069 5.76E-17 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10575 6942c055bb4d6eb2eb2e0612fffcf31b 2406 SUPERFAMILY SSF53474 2131 2399 9.57E-56 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS10575 6942c055bb4d6eb2eb2e0612fffcf31b 2406 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 509 917 1.2E-138 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS10575 6942c055bb4d6eb2eb2e0612fffcf31b 2406 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1579 1981 2.9E-133 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS10575 6942c055bb4d6eb2eb2e0612fffcf31b 2406 Pfam PF00550 Phosphopantetheine attachment site 1007 1069 1.1E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10575 6942c055bb4d6eb2eb2e0612fffcf31b 2406 Pfam PF00550 Phosphopantetheine attachment site 2067 2130 9.8E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10575 6942c055bb4d6eb2eb2e0612fffcf31b 2406 SUPERFAMILY SSF56801 1530 2077 5.36E-157 T 28-03-2018 CIG75_RS10575 6942c055bb4d6eb2eb2e0612fffcf31b 2406 Gene3D G3DSA:3.40.50.1820 2145 2401 4.6E-25 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS06040 303926ec240948f93823a3236e510c7c 783 SUPERFAMILY SSF48334 23 287 3.66E-28 T 28-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CIG75_RS06040 303926ec240948f93823a3236e510c7c 783 SMART SM00533 9 314 1.4E-18 T 28-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CIG75_RS06040 303926ec240948f93823a3236e510c7c 783 Pfam PF00488 MutS domain V 330 511 6.4E-32 T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CIG75_RS06040 303926ec240948f93823a3236e510c7c 783 Hamap MF_00092 Endonuclease MutS2 [mutS2]. 2 782 21.128 T 28-03-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 CIG75_RS06040 303926ec240948f93823a3236e510c7c 783 Gene3D G3DSA:1.10.1420.10 28 288 7.1E-4 T 28-03-2018 CIG75_RS06040 303926ec240948f93823a3236e510c7c 783 PIRSF PIRSF005814 1 783 1.5E-256 T 28-03-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 CIG75_RS06040 303926ec240948f93823a3236e510c7c 783 TIGRFAM TIGR01069 mutS2: MutS2 family protein 1 783 2.9E-236 T 28-03-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 CIG75_RS06040 303926ec240948f93823a3236e510c7c 783 Gene3D G3DSA:1.20.1420.10 507 642 0.28 T 28-03-2018 CIG75_RS06040 303926ec240948f93823a3236e510c7c 783 Pfam PF05192 MutS domain III 34 280 2.7E-6 T 28-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CIG75_RS06040 303926ec240948f93823a3236e510c7c 783 SUPERFAMILY SSF160443 706 783 1.7E-9 T 28-03-2018 IPR002625 Smr domain CIG75_RS06040 303926ec240948f93823a3236e510c7c 783 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 409 425 - T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CIG75_RS06040 303926ec240948f93823a3236e510c7c 783 SMART SM00463 705 783 5.4E-19 T 28-03-2018 IPR002625 Smr domain CIG75_RS06040 303926ec240948f93823a3236e510c7c 783 Pfam PF01713 Smr domain 708 783 6.9E-18 T 28-03-2018 IPR002625 Smr domain CIG75_RS06040 303926ec240948f93823a3236e510c7c 783 Gene3D G3DSA:3.40.50.300 290 506 4.8E-29 T 28-03-2018 CIG75_RS06040 303926ec240948f93823a3236e510c7c 783 SUPERFAMILY SSF52540 291 511 4.28E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS06040 303926ec240948f93823a3236e510c7c 783 SMART SM00534 327 512 3.3E-72 T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CIG75_RS09100 2c486fdd8dd617ceb8026fff9f7d19e4 113 Pfam PF00581 Rhodanese-like domain 16 104 3.8E-16 T 28-03-2018 IPR001763 Rhodanese-like domain CIG75_RS09100 2c486fdd8dd617ceb8026fff9f7d19e4 113 SUPERFAMILY SSF52821 11 104 1.1E-29 T 28-03-2018 IPR001763 Rhodanese-like domain CIG75_RS09100 2c486fdd8dd617ceb8026fff9f7d19e4 113 SMART SM00450 14 109 8.5E-22 T 28-03-2018 IPR001763 Rhodanese-like domain CIG75_RS09100 2c486fdd8dd617ceb8026fff9f7d19e4 113 Gene3D G3DSA:3.40.250.10 1 112 7.0E-26 T 28-03-2018 IPR001763 Rhodanese-like domain CIG75_RS10160 a065b8c77eec50b266f0dce8aeec3a64 255 SUPERFAMILY SSF53474 2 254 1.62E-59 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS10160 a065b8c77eec50b266f0dce8aeec3a64 255 Gene3D G3DSA:3.40.50.1820 3 255 3.2E-48 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS10160 a065b8c77eec50b266f0dce8aeec3a64 255 PRINTS PR00111 Alpha/beta hydrolase fold signature 91 104 8.7E-12 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CIG75_RS10160 a065b8c77eec50b266f0dce8aeec3a64 255 PRINTS PR00111 Alpha/beta hydrolase fold signature 105 118 8.7E-12 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CIG75_RS10160 a065b8c77eec50b266f0dce8aeec3a64 255 PRINTS PR00111 Alpha/beta hydrolase fold signature 200 214 8.7E-12 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CIG75_RS10160 a065b8c77eec50b266f0dce8aeec3a64 255 PRINTS PR00111 Alpha/beta hydrolase fold signature 46 61 8.7E-12 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CIG75_RS10160 a065b8c77eec50b266f0dce8aeec3a64 255 Pfam PF12697 Alpha/beta hydrolase family 23 248 2.6E-25 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CIG75_RS13030 a531296baeb8a4b6174e08784d855320 360 Gene3D G3DSA:3.50.30.20 1 139 7.0E-64 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CIG75_RS13030 a531296baeb8a4b6174e08784d855320 360 PRINTS PR00097 Anthranilate synthase component II signature 215 224 2.9E-7 T 28-03-2018 CIG75_RS13030 a531296baeb8a4b6174e08784d855320 360 PRINTS PR00097 Anthranilate synthase component II signature 242 253 2.9E-7 T 28-03-2018 CIG75_RS13030 a531296baeb8a4b6174e08784d855320 360 PRINTS PR00097 Anthranilate synthase component II signature 328 341 2.9E-7 T 28-03-2018 CIG75_RS13030 a531296baeb8a4b6174e08784d855320 360 PRINTS PR00096 Glutamine amidotransferase superfamily signature 242 253 2.1E-12 T 28-03-2018 CIG75_RS13030 a531296baeb8a4b6174e08784d855320 360 PRINTS PR00096 Glutamine amidotransferase superfamily signature 328 341 2.1E-12 T 28-03-2018 CIG75_RS13030 a531296baeb8a4b6174e08784d855320 360 PRINTS PR00096 Glutamine amidotransferase superfamily signature 215 224 2.1E-12 T 28-03-2018 CIG75_RS13030 a531296baeb8a4b6174e08784d855320 360 SUPERFAMILY SSF52021 1 142 5.49E-60 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CIG75_RS13030 a531296baeb8a4b6174e08784d855320 360 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 259 276 4.3E-35 T 28-03-2018 CIG75_RS13030 a531296baeb8a4b6174e08784d855320 360 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 212 226 4.3E-35 T 28-03-2018 CIG75_RS13030 a531296baeb8a4b6174e08784d855320 360 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 284 295 4.3E-35 T 28-03-2018 CIG75_RS13030 a531296baeb8a4b6174e08784d855320 360 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 173 187 4.3E-35 T 28-03-2018 CIG75_RS13030 a531296baeb8a4b6174e08784d855320 360 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 242 258 4.3E-35 T 28-03-2018 CIG75_RS13030 a531296baeb8a4b6174e08784d855320 360 SUPERFAMILY SSF52317 138 355 4.95E-63 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CIG75_RS13030 a531296baeb8a4b6174e08784d855320 360 SMART SM01097 1 131 1.1E-94 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CIG75_RS13030 a531296baeb8a4b6174e08784d855320 360 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 1 357 50.005 T 28-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CIG75_RS13030 a531296baeb8a4b6174e08784d855320 360 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 3 354 7.7E-152 T 28-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CIG75_RS13030 a531296baeb8a4b6174e08784d855320 360 Pfam PF00117 Glutamine amidotransferase class-I 176 351 4.9E-47 T 28-03-2018 IPR017926 Glutamine amidotransferase CIG75_RS13030 a531296baeb8a4b6174e08784d855320 360 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 3 130 9.4E-56 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CIG75_RS13030 a531296baeb8a4b6174e08784d855320 360 Gene3D G3DSA:3.40.50.880 140 358 1.0E-57 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CIG75_RS14900 a3c3cf27a798ebbb8d041ba5cdb0f31c 479 Gene3D G3DSA:3.40.120.10 1 169 9.3E-43 T 28-03-2018 CIG75_RS14900 a3c3cf27a798ebbb8d041ba5cdb0f31c 479 Gene3D G3DSA:3.40.120.10 170 276 1.1E-31 T 28-03-2018 CIG75_RS14900 a3c3cf27a798ebbb8d041ba5cdb0f31c 479 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 97 106 - T 28-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CIG75_RS14900 a3c3cf27a798ebbb8d041ba5cdb0f31c 479 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 409 471 1.2E-12 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CIG75_RS14900 a3c3cf27a798ebbb8d041ba5cdb0f31c 479 SUPERFAMILY SSF53738 255 387 7.85E-29 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CIG75_RS14900 a3c3cf27a798ebbb8d041ba5cdb0f31c 479 SUPERFAMILY SSF53738 166 268 9.42E-25 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CIG75_RS14900 a3c3cf27a798ebbb8d041ba5cdb0f31c 479 SUPERFAMILY SSF55957 375 469 4.32E-19 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CIG75_RS14900 a3c3cf27a798ebbb8d041ba5cdb0f31c 479 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 272 381 3.9E-28 T 28-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CIG75_RS14900 a3c3cf27a798ebbb8d041ba5cdb0f31c 479 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 5 139 4.3E-37 T 28-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CIG75_RS14900 a3c3cf27a798ebbb8d041ba5cdb0f31c 479 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 167 267 1.8E-28 T 28-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CIG75_RS14900 a3c3cf27a798ebbb8d041ba5cdb0f31c 479 Gene3D G3DSA:3.30.310.50 386 473 4.7E-18 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CIG75_RS14900 a3c3cf27a798ebbb8d041ba5cdb0f31c 479 Gene3D G3DSA:3.40.120.10 277 384 8.8E-29 T 28-03-2018 CIG75_RS14900 a3c3cf27a798ebbb8d041ba5cdb0f31c 479 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 184 203 8.1E-18 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CIG75_RS14900 a3c3cf27a798ebbb8d041ba5cdb0f31c 479 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 219 232 8.1E-18 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CIG75_RS14900 a3c3cf27a798ebbb8d041ba5cdb0f31c 479 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 247 262 8.1E-18 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CIG75_RS14900 a3c3cf27a798ebbb8d041ba5cdb0f31c 479 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 96 110 8.1E-18 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CIG75_RS14900 a3c3cf27a798ebbb8d041ba5cdb0f31c 479 SUPERFAMILY SSF53738 3 190 2.41E-44 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CIG75_RS11320 8ad99f5316a23fe7dae492cd833ad0f1 379 Pfam PF01590 GAF domain 41 162 1.2E-15 T 28-03-2018 IPR003018 GAF domain GO:0005515 CIG75_RS11320 8ad99f5316a23fe7dae492cd833ad0f1 379 SMART SM00065 33 179 2.8E-17 T 28-03-2018 IPR003018 GAF domain GO:0005515 CIG75_RS11320 8ad99f5316a23fe7dae492cd833ad0f1 379 SMART SM00471 196 333 2.6E-9 T 28-03-2018 IPR003607 HD/PDEase domain CIG75_RS11320 8ad99f5316a23fe7dae492cd833ad0f1 379 Gene3D G3DSA:3.30.450.40 14 173 7.3E-33 T 28-03-2018 IPR029016 GAF domain-like CIG75_RS11320 8ad99f5316a23fe7dae492cd833ad0f1 379 Pfam PF01966 HD domain 201 323 5.0E-22 T 28-03-2018 IPR006674 HD domain CIG75_RS11320 8ad99f5316a23fe7dae492cd833ad0f1 379 SUPERFAMILY SSF109604 186 364 1.22E-41 T 28-03-2018 CIG75_RS11320 8ad99f5316a23fe7dae492cd833ad0f1 379 SUPERFAMILY SSF55781 16 184 2.62E-38 T 28-03-2018 IPR029016 GAF domain-like CIG75_RS11320 8ad99f5316a23fe7dae492cd833ad0f1 379 Gene3D G3DSA:1.10.3210.10 174 373 4.0E-53 T 28-03-2018 CIG75_RS12480 63b75dc48acce7540ca64159c2103cd2 293 SUPERFAMILY SSF52540 64 289 8.9E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS12480 63b75dc48acce7540ca64159c2103cd2 293 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 39 281 4.0E-73 T 28-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 CIG75_RS12480 63b75dc48acce7540ca64159c2103cd2 293 Pfam PF16745 RsgA N-terminal domain 3 56 1.1E-20 T 28-03-2018 IPR031944 Ribosome biogenesis GTPase RsgA, N-terminal CIG75_RS12480 63b75dc48acce7540ca64159c2103cd2 293 Gene3D G3DSA:2.40.50.140 1 61 6.4E-21 T 28-03-2018 CIG75_RS12480 63b75dc48acce7540ca64159c2103cd2 293 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 2 289 35.574 T 28-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 CIG75_RS12480 63b75dc48acce7540ca64159c2103cd2 293 SUPERFAMILY SSF50249 1 63 8.57E-14 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CIG75_RS12480 63b75dc48acce7540ca64159c2103cd2 293 Gene3D G3DSA:3.40.50.300 62 224 1.2E-26 T 28-03-2018 CIG75_RS12480 63b75dc48acce7540ca64159c2103cd2 293 Gene3D G3DSA:1.10.40.50 226 293 5.4E-19 T 28-03-2018 CIG75_RS12480 63b75dc48acce7540ca64159c2103cd2 293 Pfam PF03193 RsgA GTPase 60 224 4.5E-57 T 28-03-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 CIG75_RS04980 0f5d8d9ade8e0c50846e0ce2291cc175 2358 SUPERFAMILY SSF47336 727 800 9.55E-19 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS04980 0f5d8d9ade8e0c50846e0ce2291cc175 2358 SUPERFAMILY SSF52777 1009 1289 1.67E-58 T 28-03-2018 CIG75_RS04980 0f5d8d9ade8e0c50846e0ce2291cc175 2358 Pfam PF13193 AMP-binding enzyme C-terminal domain 1713 1787 7.6E-14 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS04980 0f5d8d9ade8e0c50846e0ce2291cc175 2358 Pfam PF13193 AMP-binding enzyme C-terminal domain 631 706 1.3E-16 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS04980 0f5d8d9ade8e0c50846e0ce2291cc175 2358 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1444 1455 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS04980 0f5d8d9ade8e0c50846e0ce2291cc175 2358 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1323 1729 4.8E-126 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS04980 0f5d8d9ade8e0c50846e0ce2291cc175 2358 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 253 647 3.9E-137 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS04980 0f5d8d9ade8e0c50846e0ce2291cc175 2358 Gene3D G3DSA:3.40.50.980 1293 1449 7.4E-47 T 28-03-2018 CIG75_RS04980 0f5d8d9ade8e0c50846e0ce2291cc175 2358 Gene3D G3DSA:3.40.50.980 223 379 6.5E-52 T 28-03-2018 CIG75_RS04980 0f5d8d9ade8e0c50846e0ce2291cc175 2358 SUPERFAMILY SSF52777 825 1002 9.12E-39 T 28-03-2018 CIG75_RS04980 0f5d8d9ade8e0c50846e0ce2291cc175 2358 Pfam PF00668 Condensation domain 821 1282 1.9E-97 T 28-03-2018 IPR001242 Condensation domain CIG75_RS04980 0f5d8d9ade8e0c50846e0ce2291cc175 2358 Pfam PF00668 Condensation domain 13 85 5.1E-5 T 28-03-2018 IPR001242 Condensation domain CIG75_RS04980 0f5d8d9ade8e0c50846e0ce2291cc175 2358 Pfam PF00668 Condensation domain 1901 2346 3.1E-87 T 28-03-2018 IPR001242 Condensation domain CIG75_RS04980 0f5d8d9ade8e0c50846e0ce2291cc175 2358 Pfam PF00668 Condensation domain 142 212 7.5E-9 T 28-03-2018 IPR001242 Condensation domain CIG75_RS04980 0f5d8d9ade8e0c50846e0ce2291cc175 2358 SUPERFAMILY SSF52777 2087 2344 2.45E-47 T 28-03-2018 CIG75_RS04980 0f5d8d9ade8e0c50846e0ce2291cc175 2358 Gene3D G3DSA:1.10.1200.10 739 804 1.3E-20 T 28-03-2018 CIG75_RS04980 0f5d8d9ade8e0c50846e0ce2291cc175 2358 SUPERFAMILY SSF47336 1809 1915 3.53E-22 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS04980 0f5d8d9ade8e0c50846e0ce2291cc175 2358 SMART SM00823 Phosphopantetheine attachment site 1815 1884 0.0028 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS04980 0f5d8d9ade8e0c50846e0ce2291cc175 2358 SMART SM00823 Phosphopantetheine attachment site 735 804 7.8E-4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS04980 0f5d8d9ade8e0c50846e0ce2291cc175 2358 SUPERFAMILY SSF52777 1906 2081 3.0E-40 T 28-03-2018 CIG75_RS04980 0f5d8d9ade8e0c50846e0ce2291cc175 2358 Gene3D G3DSA:3.30.300.30 1700 1820 7.8E-40 T 28-03-2018 CIG75_RS04980 0f5d8d9ade8e0c50846e0ce2291cc175 2358 Gene3D G3DSA:3.30.300.30 618 738 1.3E-39 T 28-03-2018 CIG75_RS04980 0f5d8d9ade8e0c50846e0ce2291cc175 2358 Gene3D G3DSA:2.30.38.10 531 613 9.3E-25 T 28-03-2018 CIG75_RS04980 0f5d8d9ade8e0c50846e0ce2291cc175 2358 Gene3D G3DSA:2.30.38.10 1615 1695 4.2E-24 T 28-03-2018 CIG75_RS04980 0f5d8d9ade8e0c50846e0ce2291cc175 2358 Gene3D G3DSA:1.10.1200.10 1821 1888 2.8E-23 T 28-03-2018 CIG75_RS04980 0f5d8d9ade8e0c50846e0ce2291cc175 2358 ProSitePatterns PS00012 Phosphopantetheine attachment site. 759 774 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS04980 0f5d8d9ade8e0c50846e0ce2291cc175 2358 SUPERFAMILY SSF56801 200 748 1.06E-164 T 28-03-2018 CIG75_RS04980 0f5d8d9ade8e0c50846e0ce2291cc175 2358 Gene3D G3DSA:3.40.50.980 1450 1612 2.7E-34 T 28-03-2018 CIG75_RS04980 0f5d8d9ade8e0c50846e0ce2291cc175 2358 Gene3D G3DSA:3.40.50.980 380 525 1.0E-36 T 28-03-2018 CIG75_RS04980 0f5d8d9ade8e0c50846e0ce2291cc175 2358 Pfam PF00550 Phosphopantetheine attachment site 738 799 9.2E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS04980 0f5d8d9ade8e0c50846e0ce2291cc175 2358 Pfam PF00550 Phosphopantetheine attachment site 1817 1880 1.5E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS04980 0f5d8d9ade8e0c50846e0ce2291cc175 2358 Gene3D G3DSA:3.30.559.10 1889 2102 9.4E-34 T 28-03-2018 CIG75_RS04980 0f5d8d9ade8e0c50846e0ce2291cc175 2358 Gene3D G3DSA:3.30.559.10 805 1024 7.0E-33 T 28-03-2018 CIG75_RS04980 0f5d8d9ade8e0c50846e0ce2291cc175 2358 SUPERFAMILY SSF52777 10 195 1.56E-21 T 28-03-2018 CIG75_RS04980 0f5d8d9ade8e0c50846e0ce2291cc175 2358 SUPERFAMILY SSF56801 1258 1827 4.84E-162 T 28-03-2018 CIG75_RS04980 0f5d8d9ade8e0c50846e0ce2291cc175 2358 ProSitePatterns PS00455 Putative AMP-binding domain signature. 374 385 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS04980 0f5d8d9ade8e0c50846e0ce2291cc175 2358 Pfam PF00501 AMP-binding enzyme 232 623 1.1E-110 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS04980 0f5d8d9ade8e0c50846e0ce2291cc175 2358 Pfam PF00501 AMP-binding enzyme 1302 1705 9.7E-94 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS03500 af3e0fb5e3f326509947c0fd32fc5d56 177 Pfam PF02417 Chromate transporter 4 169 1.8E-41 T 28-03-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 CIG75_RS06375 e527482ae49af8d239b2948b5eda0de3 529 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 361 501 2.5E-21 T 28-03-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain CIG75_RS06375 e527482ae49af8d239b2948b5eda0de3 529 TIGRFAM TIGR02900 spore_V_B: stage V sporulation protein B 7 495 9.5E-140 T 28-03-2018 IPR014249 Sporulation stage V protein B CIG75_RS06375 e527482ae49af8d239b2948b5eda0de3 529 PIRSF PIRSF038958 2 516 1.3E-149 T 28-03-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type CIG75_RS06375 e527482ae49af8d239b2948b5eda0de3 529 Pfam PF01943 Polysaccharide biosynthesis protein 7 310 2.7E-41 T 28-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 CIG75_RS08125 cc51882958305954bb1b374cf8c546b7 100 ProSitePatterns PS00831 Ribosomal protein L27 signature. 42 56 - T 28-03-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS08125 cc51882958305954bb1b374cf8c546b7 100 Pfam PF01016 Ribosomal L27 protein 10 89 4.6E-34 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS08125 cc51882958305954bb1b374cf8c546b7 100 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 37 77 1.0E-13 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS08125 cc51882958305954bb1b374cf8c546b7 100 PRINTS PR00063 Ribosomal protein L27 signature 37 61 1.5E-37 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS08125 cc51882958305954bb1b374cf8c546b7 100 PRINTS PR00063 Ribosomal protein L27 signature 62 86 1.5E-37 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS08125 cc51882958305954bb1b374cf8c546b7 100 PRINTS PR00063 Ribosomal protein L27 signature 12 36 1.5E-37 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS08125 cc51882958305954bb1b374cf8c546b7 100 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 9 92 27.333 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS08125 cc51882958305954bb1b374cf8c546b7 100 TIGRFAM TIGR00062 L27: ribosomal protein bL27 9 89 7.1E-38 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS08125 cc51882958305954bb1b374cf8c546b7 100 Gene3D G3DSA:2.40.50.100 28 92 3.2E-29 T 28-03-2018 CIG75_RS08125 cc51882958305954bb1b374cf8c546b7 100 SUPERFAMILY SSF110324 10 91 2.65E-32 T 28-03-2018 CIG75_RS16080 59b4c9e672018806f93a1e59c7285b47 1081 Pfam PF02310 B12 binding domain 13 110 8.6E-12 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CIG75_RS16080 59b4c9e672018806f93a1e59c7285b47 1081 Gene3D G3DSA:3.40.50.280 8 162 3.3E-26 T 28-03-2018 CIG75_RS16080 59b4c9e672018806f93a1e59c7285b47 1081 Pfam PF01642 Methylmalonyl-CoA mutase 552 1075 3.8E-140 T 28-03-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CIG75_RS16080 59b4c9e672018806f93a1e59c7285b47 1081 Gene3D G3DSA:3.40.50.300 196 408 9.5E-29 T 28-03-2018 CIG75_RS16080 59b4c9e672018806f93a1e59c7285b47 1081 SUPERFAMILY SSF52242 4 143 3.27E-40 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CIG75_RS16080 59b4c9e672018806f93a1e59c7285b47 1081 Hamap MF_02050 Fused isobutyryl-CoA mutase [icmF]. 11 1081 17.156 T 28-03-2018 IPR033669 Fused isobutyryl-CoA mutase GO:0003924|GO:0005525|GO:0006637|GO:0031419|GO:0034784|GO:0047727 CIG75_RS16080 59b4c9e672018806f93a1e59c7285b47 1081 Pfam PF03308 ArgK protein 166 369 4.1E-42 T 28-03-2018 CIG75_RS16080 59b4c9e672018806f93a1e59c7285b47 1081 Gene3D G3DSA:3.20.20.240 539 1077 2.2E-195 T 28-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CIG75_RS16080 59b4c9e672018806f93a1e59c7285b47 1081 SUPERFAMILY SSF51703 501 1077 3.4E-150 T 28-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CIG75_RS16080 59b4c9e672018806f93a1e59c7285b47 1081 SUPERFAMILY SSF52540 127 460 1.93E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS15915 c5cb5f76e5f8de78119ef345ff1abf91 290 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 11 90 1.4E-11 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CIG75_RS15915 c5cb5f76e5f8de78119ef345ff1abf91 290 Gene3D G3DSA:1.10.150.130 6 98 1.8E-15 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CIG75_RS15915 c5cb5f76e5f8de78119ef345ff1abf91 290 Pfam PF00589 Phage integrase family 115 266 4.9E-21 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CIG75_RS15915 c5cb5f76e5f8de78119ef345ff1abf91 290 Gene3D G3DSA:1.10.443.10 113 269 3.3E-25 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CIG75_RS15915 c5cb5f76e5f8de78119ef345ff1abf91 290 SUPERFAMILY SSF56349 14 267 7.06E-31 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CIG75_RS02625 816f44bb835b14f0abf7b2d0907dbca9 574 SUPERFAMILY SSF55957 515 572 2.09E-13 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CIG75_RS02625 816f44bb835b14f0abf7b2d0907dbca9 574 Gene3D G3DSA:3.30.310.50 469 574 2.0E-20 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CIG75_RS02625 816f44bb835b14f0abf7b2d0907dbca9 574 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 140 149 - T 28-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CIG75_RS02625 816f44bb835b14f0abf7b2d0907dbca9 574 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 139 153 1.6E-7 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CIG75_RS02625 816f44bb835b14f0abf7b2d0907dbca9 574 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 231 250 1.6E-7 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CIG75_RS02625 816f44bb835b14f0abf7b2d0907dbca9 574 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 298 313 1.6E-7 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CIG75_RS02625 816f44bb835b14f0abf7b2d0907dbca9 574 Gene3D G3DSA:3.40.120.10 17 213 3.1E-56 T 28-03-2018 CIG75_RS02625 816f44bb835b14f0abf7b2d0907dbca9 574 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 504 557 7.0E-10 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CIG75_RS02625 816f44bb835b14f0abf7b2d0907dbca9 574 SUPERFAMILY SSF53738 31 238 7.46E-44 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CIG75_RS02625 816f44bb835b14f0abf7b2d0907dbca9 574 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 42 181 7.2E-40 T 28-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CIG75_RS02625 816f44bb835b14f0abf7b2d0907dbca9 574 SUPERFAMILY SSF53738 306 457 9.81E-32 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CIG75_RS02625 816f44bb835b14f0abf7b2d0907dbca9 574 Gene3D G3DSA:3.40.120.10 339 457 4.5E-37 T 28-03-2018 CIG75_RS02625 816f44bb835b14f0abf7b2d0907dbca9 574 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 211 314 9.5E-24 T 28-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CIG75_RS02625 816f44bb835b14f0abf7b2d0907dbca9 574 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 326 453 5.6E-23 T 28-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CIG75_RS02625 816f44bb835b14f0abf7b2d0907dbca9 574 SUPERFAMILY SSF53738 210 317 5.1E-20 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CIG75_RS02625 816f44bb835b14f0abf7b2d0907dbca9 574 Gene3D G3DSA:3.40.120.10 214 338 7.9E-30 T 28-03-2018 CIG75_RS16590 119a7f4151163bde91a86f79aa450d15 267 Pfam PF00459 Inositol monophosphatase family 6 245 5.9E-51 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CIG75_RS16590 119a7f4151163bde91a86f79aa450d15 267 SUPERFAMILY SSF56655 8 262 3.4E-58 T 28-03-2018 CIG75_RS16590 119a7f4151163bde91a86f79aa450d15 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 63 79 3.9E-28 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CIG75_RS16590 119a7f4151163bde91a86f79aa450d15 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 209 233 3.9E-28 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CIG75_RS16590 119a7f4151163bde91a86f79aa450d15 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 41 61 3.9E-28 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CIG75_RS16590 119a7f4151163bde91a86f79aa450d15 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 83 99 3.9E-28 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CIG75_RS16590 119a7f4151163bde91a86f79aa450d15 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 132 155 3.9E-28 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CIG75_RS16590 119a7f4151163bde91a86f79aa450d15 267 Gene3D G3DSA:3.40.190.80 153 267 2.0E-13 T 28-03-2018 CIG75_RS16590 119a7f4151163bde91a86f79aa450d15 267 Gene3D G3DSA:3.30.540.10 1 142 9.3E-40 T 28-03-2018 CIG75_RS17510 849b768108d16238860d99e7049a4441 138 Pfam PF01230 HIT domain 15 105 1.9E-16 T 28-03-2018 IPR001310 Histidine triad (HIT) protein CIG75_RS17510 849b768108d16238860d99e7049a4441 138 SUPERFAMILY SSF54197 1 115 4.49E-32 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 CIG75_RS17510 849b768108d16238860d99e7049a4441 138 Gene3D G3DSA:3.30.428.10 1 136 3.1E-28 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 CIG75_RS13665 1e8940a9c0685377c41ec50eb7d12c5c 102 Gene3D G3DSA:3.30.70.20 72 100 0.0014 T 28-03-2018 CIG75_RS13665 1e8940a9c0685377c41ec50eb7d12c5c 102 PIRSF PIRSF036548 9 102 9.4E-24 T 28-03-2018 IPR012206 Ferredoxin-like, FixX GO:0005506 CIG75_RS13665 1e8940a9c0685377c41ec50eb7d12c5c 102 SUPERFAMILY SSF54862 31 101 2.07E-17 T 28-03-2018 CIG75_RS13665 1e8940a9c0685377c41ec50eb7d12c5c 102 Pfam PF05187 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S 24 100 1.2E-13 T 28-03-2018 CIG75_RS13665 1e8940a9c0685377c41ec50eb7d12c5c 102 Gene3D G3DSA:3.30.70.20 48 71 0.0035 T 28-03-2018 CIG75_RS13665 1e8940a9c0685377c41ec50eb7d12c5c 102 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 71 82 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CIG75_RS13665 1e8940a9c0685377c41ec50eb7d12c5c 102 Gene3D G3DSA:3.30.70.20 6 47 0.1 T 28-03-2018 CIG75_RS09790 4f5340f83323b54357d485eb89367746 1450 Gene3D G3DSA:3.40.366.10 536 669 1.9E-43 T 28-03-2018 CIG75_RS09790 4f5340f83323b54357d485eb89367746 1450 Gene3D G3DSA:3.40.50.720 918 1040 0.087 T 28-03-2018 CIG75_RS09790 4f5340f83323b54357d485eb89367746 1450 Gene3D G3DSA:1.10.1200.10 1373 1448 2.4E-21 T 28-03-2018 CIG75_RS09790 4f5340f83323b54357d485eb89367746 1450 Gene3D G3DSA:3.40.50.720 1109 1372 1.5E-31 T 28-03-2018 CIG75_RS09790 4f5340f83323b54357d485eb89367746 1450 SUPERFAMILY SSF51735 897 1099 1.97E-24 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS09790 4f5340f83323b54357d485eb89367746 1450 Gene3D G3DSA:3.40.47.10 283 446 7.7E-56 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS09790 4f5340f83323b54357d485eb89367746 1450 Gene3D G3DSA:3.40.366.10 710 837 6.2E-24 T 28-03-2018 CIG75_RS09790 4f5340f83323b54357d485eb89367746 1450 Gene3D G3DSA:3.30.70.250 670 709 1.6E-15 T 28-03-2018 CIG75_RS09790 4f5340f83323b54357d485eb89367746 1450 Gene3D G3DSA:3.40.47.10 12 279 1.3E-72 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS09790 4f5340f83323b54357d485eb89367746 1450 SMART SM00825 Beta-ketoacyl synthase 19 444 9.5E-171 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CIG75_RS09790 4f5340f83323b54357d485eb89367746 1450 SUPERFAMILY SSF52151 724 817 6.02E-65 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CIG75_RS09790 4f5340f83323b54357d485eb89367746 1450 SUPERFAMILY SSF52151 536 664 6.02E-65 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CIG75_RS09790 4f5340f83323b54357d485eb89367746 1450 Pfam PF08659 KR domain 1117 1295 1.1E-41 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS09790 4f5340f83323b54357d485eb89367746 1450 SUPERFAMILY SSF55048 661 720 1.83E-9 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CIG75_RS09790 4f5340f83323b54357d485eb89367746 1450 SUPERFAMILY SSF51735 1115 1293 3.46E-28 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS09790 4f5340f83323b54357d485eb89367746 1450 SUPERFAMILY SSF47336 1362 1435 3.01E-20 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS09790 4f5340f83323b54357d485eb89367746 1450 SMART SM00823 Phosphopantetheine attachment site 1370 1439 1.5E-7 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS09790 4f5340f83323b54357d485eb89367746 1450 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 540 828 1.5E-95 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CIG75_RS09790 4f5340f83323b54357d485eb89367746 1450 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 275 392 2.7E-38 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CIG75_RS09790 4f5340f83323b54357d485eb89367746 1450 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 18 267 1.3E-71 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CIG75_RS09790 4f5340f83323b54357d485eb89367746 1450 Pfam PF00698 Acyl transferase domain 539 848 1.3E-54 T 28-03-2018 IPR014043 Acyl transferase CIG75_RS09790 4f5340f83323b54357d485eb89367746 1450 Pfam PF00550 Phosphopantetheine attachment site 1372 1434 7.6E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS09790 4f5340f83323b54357d485eb89367746 1450 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1117 1297 1.6E-17 T 28-03-2018 CIG75_RS09790 4f5340f83323b54357d485eb89367746 1450 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 405 506 1.2E-18 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS09790 4f5340f83323b54357d485eb89367746 1450 SUPERFAMILY SSF53901 419 440 2.42E-82 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS09790 4f5340f83323b54357d485eb89367746 1450 SUPERFAMILY SSF53901 163 385 2.42E-82 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS09790 4f5340f83323b54357d485eb89367746 1450 SUPERFAMILY SSF53901 14 135 2.42E-82 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS20455 d3ad7deb992e5ad6989b3b7957a42337 79 SMART SM00966 8 51 4.7E-10 T 28-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CIG75_RS20455 d3ad7deb992e5ad6989b3b7957a42337 79 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 8 48 5.3E-10 T 28-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CIG75_RS20455 d3ad7deb992e5ad6989b3b7957a42337 79 Gene3D G3DSA:2.10.260.10 1 48 2.5E-20 T 28-03-2018 CIG75_RS20455 d3ad7deb992e5ad6989b3b7957a42337 79 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 8 50 1.7E-11 T 28-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CIG75_RS20455 d3ad7deb992e5ad6989b3b7957a42337 79 SUPERFAMILY SSF89447 1 53 3.4E-17 T 28-03-2018 CIG75_RS04040 d3ff5489d8cf78aac421362f5f03a05c 166 Gene3D G3DSA:3.40.630.30 3 164 2.2E-10 T 28-03-2018 CIG75_RS04040 d3ff5489d8cf78aac421362f5f03a05c 166 Pfam PF00583 Acetyltransferase (GNAT) family 46 134 1.9E-9 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CIG75_RS04040 d3ff5489d8cf78aac421362f5f03a05c 166 SUPERFAMILY SSF55729 43 134 8.51E-11 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CIG75_RS15610 91981784644a4083553a65c427fa2dbd 159 Pfam PF07291 Methylamine utilisation protein MauE 28 148 2.8E-14 T 28-03-2018 IPR009908 Methylamine utilisation protein, MauE GO:0016021|GO:0030416 CIG75_RS02590 6c091c673f75bf5c09709e7b214215cf 1701 Gene3D G3DSA:3.40.50.980 167 324 4.9E-31 T 28-03-2018 CIG75_RS02590 6c091c673f75bf5c09709e7b214215cf 1701 Pfam PF00501 AMP-binding enzyme 19 417 5.8E-89 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS02590 6c091c673f75bf5c09709e7b214215cf 1701 Pfam PF00501 AMP-binding enzyme 1078 1479 1.1E-94 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS02590 6c091c673f75bf5c09709e7b214215cf 1701 Gene3D G3DSA:3.30.300.30 1474 1595 8.5E-36 T 28-03-2018 CIG75_RS02590 6c091c673f75bf5c09709e7b214215cf 1701 Gene3D G3DSA:3.30.300.30 412 531 1.2E-33 T 28-03-2018 CIG75_RS02590 6c091c673f75bf5c09709e7b214215cf 1701 Pfam PF00668 Condensation domain 616 1057 1.8E-105 T 28-03-2018 IPR001242 Condensation domain CIG75_RS02590 6c091c673f75bf5c09709e7b214215cf 1701 SUPERFAMILY SSF56801 1037 1603 6.8E-147 T 28-03-2018 CIG75_RS02590 6c091c673f75bf5c09709e7b214215cf 1701 Gene3D G3DSA:3.40.50.980 1221 1375 3.4E-36 T 28-03-2018 CIG75_RS02590 6c091c673f75bf5c09709e7b214215cf 1701 Gene3D G3DSA:3.40.50.980 11 166 1.5E-44 T 28-03-2018 CIG75_RS02590 6c091c673f75bf5c09709e7b214215cf 1701 Gene3D G3DSA:3.40.50.980 1073 1220 2.7E-43 T 28-03-2018 CIG75_RS02590 6c091c673f75bf5c09709e7b214215cf 1701 Gene3D G3DSA:3.30.559.10 605 814 1.0E-37 T 28-03-2018 CIG75_RS02590 6c091c673f75bf5c09709e7b214215cf 1701 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1219 1230 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS02590 6c091c673f75bf5c09709e7b214215cf 1701 Gene3D G3DSA:2.30.38.10 325 407 5.6E-20 T 28-03-2018 CIG75_RS02590 6c091c673f75bf5c09709e7b214215cf 1701 Gene3D G3DSA:2.30.38.10 1387 1469 6.4E-21 T 28-03-2018 CIG75_RS02590 6c091c673f75bf5c09709e7b214215cf 1701 Gene3D G3DSA:1.10.1200.10 532 598 9.8E-16 T 28-03-2018 CIG75_RS02590 6c091c673f75bf5c09709e7b214215cf 1701 Gene3D G3DSA:1.10.1200.10 1596 1662 1.1E-22 T 28-03-2018 CIG75_RS02590 6c091c673f75bf5c09709e7b214215cf 1701 SUPERFAMILY SSF52777 801 1045 1.89E-61 T 28-03-2018 CIG75_RS02590 6c091c673f75bf5c09709e7b214215cf 1701 ProSitePatterns PS00012 Phosphopantetheine attachment site. 550 565 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS02590 6c091c673f75bf5c09709e7b214215cf 1701 Pfam PF00550 Phosphopantetheine attachment site 529 591 1.6E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS02590 6c091c673f75bf5c09709e7b214215cf 1701 Pfam PF00550 Phosphopantetheine attachment site 1593 1654 6.9E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS02590 6c091c673f75bf5c09709e7b214215cf 1701 SUPERFAMILY SSF56801 14 538 1.96E-141 T 28-03-2018 CIG75_RS02590 6c091c673f75bf5c09709e7b214215cf 1701 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1099 1503 2.6E-123 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS02590 6c091c673f75bf5c09709e7b214215cf 1701 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 40 441 1.7E-125 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS02590 6c091c673f75bf5c09709e7b214215cf 1701 SUPERFAMILY SSF47336 519 591 4.58E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS02590 6c091c673f75bf5c09709e7b214215cf 1701 SUPERFAMILY SSF52777 616 793 2.0E-43 T 28-03-2018 CIG75_RS02590 6c091c673f75bf5c09709e7b214215cf 1701 SMART SM00823 Phosphopantetheine attachment site 526 595 0.011 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS02590 6c091c673f75bf5c09709e7b214215cf 1701 SMART SM00823 Phosphopantetheine attachment site 1590 1659 0.068 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS02590 6c091c673f75bf5c09709e7b214215cf 1701 SUPERFAMILY SSF47336 1586 1655 1.96E-19 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS02590 6c091c673f75bf5c09709e7b214215cf 1701 Pfam PF13193 AMP-binding enzyme C-terminal domain 425 500 9.0E-6 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS02590 6c091c673f75bf5c09709e7b214215cf 1701 Pfam PF13193 AMP-binding enzyme C-terminal domain 1488 1562 6.2E-14 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS02590 6c091c673f75bf5c09709e7b214215cf 1701 ProSitePatterns PS00455 Putative AMP-binding domain signature. 161 172 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS02590 6c091c673f75bf5c09709e7b214215cf 1701 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1614 1629 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS02810 e76c14e0bc54a60e0f3afa7095509840 1092 ProSitePatterns PS00455 Putative AMP-binding domain signature. 624 635 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS02810 e76c14e0bc54a60e0f3afa7095509840 1092 Gene3D G3DSA:3.30.300.30 875 991 1.4E-31 T 28-03-2018 CIG75_RS02810 e76c14e0bc54a60e0f3afa7095509840 1092 SMART SM00823 Phosphopantetheine attachment site 986 1057 4.3E-7 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS02810 e76c14e0bc54a60e0f3afa7095509840 1092 Gene3D G3DSA:3.40.50.980 477 629 8.4E-46 T 28-03-2018 CIG75_RS02810 e76c14e0bc54a60e0f3afa7095509840 1092 Gene3D G3DSA:2.30.38.10 789 869 6.4E-25 T 28-03-2018 CIG75_RS02810 e76c14e0bc54a60e0f3afa7095509840 1092 Gene3D G3DSA:3.40.50.980 630 787 6.9E-31 T 28-03-2018 CIG75_RS02810 e76c14e0bc54a60e0f3afa7095509840 1092 SUPERFAMILY SSF56801 445 999 2.88E-146 T 28-03-2018 CIG75_RS02810 e76c14e0bc54a60e0f3afa7095509840 1092 Pfam PF00501 AMP-binding enzyme 486 879 3.6E-95 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS02810 e76c14e0bc54a60e0f3afa7095509840 1092 Gene3D G3DSA:3.30.559.10 9 218 1.9E-41 T 28-03-2018 CIG75_RS02810 e76c14e0bc54a60e0f3afa7095509840 1092 SUPERFAMILY SSF52777 34 206 2.0E-45 T 28-03-2018 CIG75_RS02810 e76c14e0bc54a60e0f3afa7095509840 1092 Gene3D G3DSA:1.10.1200.10 992 1083 5.7E-21 T 28-03-2018 CIG75_RS02810 e76c14e0bc54a60e0f3afa7095509840 1092 SUPERFAMILY SSF47336 982 1072 1.57E-17 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS02810 e76c14e0bc54a60e0f3afa7095509840 1092 Pfam PF00668 Condensation domain 29 462 2.3E-111 T 28-03-2018 IPR001242 Condensation domain CIG75_RS02810 e76c14e0bc54a60e0f3afa7095509840 1092 Pfam PF00550 Phosphopantetheine attachment site 988 1053 7.3E-16 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS02810 e76c14e0bc54a60e0f3afa7095509840 1092 SUPERFAMILY SSF52777 212 449 2.0E-54 T 28-03-2018 CIG75_RS02810 e76c14e0bc54a60e0f3afa7095509840 1092 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 507 903 4.0E-125 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS15665 35a9fb69e390a635a6858d8e1f5c459f 264 SUPERFAMILY SSF56784 1 258 8.51E-59 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS15665 35a9fb69e390a635a6858d8e1f5c459f 264 Gene3D G3DSA:3.40.50.1000 1 261 5.6E-39 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS15665 35a9fb69e390a635a6858d8e1f5c459f 264 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 4 251 7.2E-47 T 28-03-2018 IPR000150 Cof family GO:0016787 CIG75_RS15665 35a9fb69e390a635a6858d8e1f5c459f 264 Pfam PF08282 haloacid dehalogenase-like hydrolase 5 251 3.3E-48 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS01270 fe5f41887d813ab2b721c2a80c1ccbd8 409 Gene3D G3DSA:1.10.287.130 186 256 1.4E-12 T 28-03-2018 CIG75_RS01270 fe5f41887d813ab2b721c2a80c1ccbd8 409 SMART SM00387 302 409 1.0E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS01270 fe5f41887d813ab2b721c2a80c1ccbd8 409 SMART SM00086 139 181 0.009 T 28-03-2018 IPR001610 PAC motif CIG75_RS01270 fe5f41887d813ab2b721c2a80c1ccbd8 409 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 304 406 1.3E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS01270 fe5f41887d813ab2b721c2a80c1ccbd8 409 Pfam PF08448 PAS fold 74 183 1.0E-13 T 28-03-2018 IPR013656 PAS fold-4 CIG75_RS01270 fe5f41887d813ab2b721c2a80c1ccbd8 409 SUPERFAMILY SSF55874 263 407 1.7E-35 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS01270 fe5f41887d813ab2b721c2a80c1ccbd8 409 SMART SM00388 196 260 1.1E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CIG75_RS01270 fe5f41887d813ab2b721c2a80c1ccbd8 409 Gene3D G3DSA:3.30.450.20 49 185 6.1E-27 T 28-03-2018 CIG75_RS01270 fe5f41887d813ab2b721c2a80c1ccbd8 409 SUPERFAMILY SSF47384 189 260 2.94E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CIG75_RS01270 fe5f41887d813ab2b721c2a80c1ccbd8 409 SMART SM00091 67 133 3.7E-5 T 28-03-2018 IPR000014 PAS domain CIG75_RS01270 fe5f41887d813ab2b721c2a80c1ccbd8 409 Pfam PF00512 His Kinase A (phospho-acceptor) domain 198 258 3.6E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CIG75_RS01270 fe5f41887d813ab2b721c2a80c1ccbd8 409 PRINTS PR00344 Bacterial sensor protein C-terminal signature 358 368 5.2E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS01270 fe5f41887d813ab2b721c2a80c1ccbd8 409 PRINTS PR00344 Bacterial sensor protein C-terminal signature 340 354 5.2E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS01270 fe5f41887d813ab2b721c2a80c1ccbd8 409 PRINTS PR00344 Bacterial sensor protein C-terminal signature 393 406 5.2E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS01270 fe5f41887d813ab2b721c2a80c1ccbd8 409 PRINTS PR00344 Bacterial sensor protein C-terminal signature 369 387 5.2E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS01270 fe5f41887d813ab2b721c2a80c1ccbd8 409 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 66 187 7.3E-26 T 28-03-2018 IPR000014 PAS domain CIG75_RS01270 fe5f41887d813ab2b721c2a80c1ccbd8 409 Gene3D G3DSA:3.30.565.10 258 409 7.1E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS01270 fe5f41887d813ab2b721c2a80c1ccbd8 409 SUPERFAMILY SSF55785 56 178 2.44E-23 T 28-03-2018 IPR000014 PAS domain CIG75_RS18855 de34c6eb118ba6ac2c45fa31f024a37d 289 PIRSF PIRSF000728 12 287 9.9E-100 T 28-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CIG75_RS18855 de34c6eb118ba6ac2c45fa31f024a37d 289 TIGRFAM TIGR00761 argB: acetylglutamate kinase 30 262 1.1E-75 T 28-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CIG75_RS18855 de34c6eb118ba6ac2c45fa31f024a37d 289 Pfam PF00696 Amino acid kinase family 28 264 7.1E-48 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CIG75_RS18855 de34c6eb118ba6ac2c45fa31f024a37d 289 Hamap MF_00082_B Acetylglutamate kinase [argB]. 26 287 34.938 T 28-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CIG75_RS18855 de34c6eb118ba6ac2c45fa31f024a37d 289 SUPERFAMILY SSF53633 6 286 1.83E-86 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CIG75_RS18855 de34c6eb118ba6ac2c45fa31f024a37d 289 Gene3D G3DSA:3.40.1160.10 1 289 6.8E-75 T 28-03-2018 CIG75_RS19650 ebbcf74cd1c048ff761c40f8105ca259 165 SUPERFAMILY SSF54768 7 75 3.66E-24 T 28-03-2018 CIG75_RS19650 ebbcf74cd1c048ff761c40f8105ca259 165 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 162 36.146 T 28-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 CIG75_RS19650 ebbcf74cd1c048ff761c40f8105ca259 165 Pfam PF03719 Ribosomal protein S5, C-terminal domain 86 156 1.2E-31 T 28-03-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 CIG75_RS19650 ebbcf74cd1c048ff761c40f8105ca259 165 Gene3D G3DSA:3.30.160.20 9 71 4.1E-30 T 28-03-2018 CIG75_RS19650 ebbcf74cd1c048ff761c40f8105ca259 165 Gene3D G3DSA:3.30.230.10 75 165 9.8E-34 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CIG75_RS19650 ebbcf74cd1c048ff761c40f8105ca259 165 ProSitePatterns PS00585 Ribosomal protein S5 signature. 27 59 - T 28-03-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site CIG75_RS19650 ebbcf74cd1c048ff761c40f8105ca259 165 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 9 162 1.7E-70 T 28-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 CIG75_RS19650 ebbcf74cd1c048ff761c40f8105ca259 165 Pfam PF00333 Ribosomal protein S5, N-terminal domain 10 74 2.5E-31 T 28-03-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 CIG75_RS19650 ebbcf74cd1c048ff761c40f8105ca259 165 SUPERFAMILY SSF54211 79 158 1.49E-26 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CIG75_RS01690 da2a4e00b48c5fbc6d420245f56d7dc5 560 Gene3D G3DSA:3.40.50.300 12 232 8.0E-95 T 28-03-2018 CIG75_RS01690 da2a4e00b48c5fbc6d420245f56d7dc5 560 Gene3D G3DSA:3.40.50.300 233 446 5.6E-76 T 28-03-2018 CIG75_RS01690 da2a4e00b48c5fbc6d420245f56d7dc5 560 SUPERFAMILY SSF52540 4 558 6.64E-244 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS01690 da2a4e00b48c5fbc6d420245f56d7dc5 560 Pfam PF01268 Formate--tetrahydrofolate ligase 2 560 3.1E-272 T 28-03-2018 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CIG75_RS01690 da2a4e00b48c5fbc6d420245f56d7dc5 560 ProSitePatterns PS00722 Formate--tetrahydrofolate ligase signature 2. 332 343 - T 28-03-2018 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CIG75_RS01690 da2a4e00b48c5fbc6d420245f56d7dc5 560 Gene3D G3DSA:3.10.410.10 448 536 2.9E-39 T 28-03-2018 CIG75_RS01690 da2a4e00b48c5fbc6d420245f56d7dc5 560 ProSitePatterns PS00721 Formate--tetrahydrofolate ligase signature 1. 107 117 - T 28-03-2018 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CIG75_RS01690 da2a4e00b48c5fbc6d420245f56d7dc5 560 Hamap MF_01543 Formate--tetrahydrofolate ligase [fhs]. 1 560 49.423 T 28-03-2018 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CIG75_RS01530 d67fd047354cb969b70085b782196fdf 465 Pfam PF08448 PAS fold 7 113 8.4E-12 T 28-03-2018 IPR013656 PAS fold-4 CIG75_RS01530 d67fd047354cb969b70085b782196fdf 465 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 442 462 4.4E-7 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CIG75_RS01530 d67fd047354cb969b70085b782196fdf 465 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 425 442 4.4E-7 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CIG75_RS01530 d67fd047354cb969b70085b782196fdf 465 Gene3D G3DSA:1.10.10.60 392 460 8.8E-16 T 28-03-2018 CIG75_RS01530 d67fd047354cb969b70085b782196fdf 465 Pfam PF02954 Bacterial regulatory protein, Fis family 419 458 4.2E-13 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CIG75_RS01530 d67fd047354cb969b70085b782196fdf 465 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 234 249 - T 28-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CIG75_RS01530 d67fd047354cb969b70085b782196fdf 465 Gene3D G3DSA:1.10.8.60 321 391 1.5E-22 T 28-03-2018 CIG75_RS01530 d67fd047354cb969b70085b782196fdf 465 Gene3D G3DSA:3.30.450.20 1 127 1.2E-17 T 28-03-2018 CIG75_RS01530 d67fd047354cb969b70085b782196fdf 465 SUPERFAMILY SSF46689 361 458 5.73E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CIG75_RS01530 d67fd047354cb969b70085b782196fdf 465 Pfam PF00158 Sigma-54 interaction domain 150 314 4.1E-62 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CIG75_RS01530 d67fd047354cb969b70085b782196fdf 465 SUPERFAMILY SSF55785 1 103 1.5E-16 T 28-03-2018 IPR000014 PAS domain CIG75_RS01530 d67fd047354cb969b70085b782196fdf 465 SMART SM00382 169 311 2.1E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS01530 d67fd047354cb969b70085b782196fdf 465 SMART SM00091 1 68 8.1E-6 T 28-03-2018 IPR000014 PAS domain CIG75_RS01530 d67fd047354cb969b70085b782196fdf 465 SUPERFAMILY SSF52540 149 392 2.11E-67 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS01530 d67fd047354cb969b70085b782196fdf 465 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 361 370 - T 28-03-2018 IPR025944 Sigma-54 interaction domain, conserved site CIG75_RS01530 d67fd047354cb969b70085b782196fdf 465 Gene3D G3DSA:3.40.50.300 145 320 2.0E-27 T 28-03-2018 CIG75_RS01530 d67fd047354cb969b70085b782196fdf 465 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 1 119 2.0E-13 T 28-03-2018 IPR000014 PAS domain CIG75_RS06495 4109f76cd3f0469e2c03a0fccbda06ef 398 Gene3D G3DSA:1.20.1250.20 203 393 9.4E-21 T 28-03-2018 CIG75_RS06495 4109f76cd3f0469e2c03a0fccbda06ef 398 TIGRFAM TIGR00896 CynX: cyanate transporter 14 368 7.8E-129 T 28-03-2018 IPR004747 Cyanate transport system protein GO:0016021 CIG75_RS06495 4109f76cd3f0469e2c03a0fccbda06ef 398 Gene3D G3DSA:1.20.1250.20 5 202 1.5E-20 T 28-03-2018 CIG75_RS06495 4109f76cd3f0469e2c03a0fccbda06ef 398 SUPERFAMILY SSF103473 5 386 3.92E-47 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS06495 4109f76cd3f0469e2c03a0fccbda06ef 398 Pfam PF07690 Major Facilitator Superfamily 20 350 2.0E-24 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CIG75_RS11105 a92c50abaf5cb919314fb96ec031f3a7 308 Pfam PF00005 ABC transporter 18 160 4.0E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS11105 a92c50abaf5cb919314fb96ec031f3a7 308 Gene3D G3DSA:3.40.50.300 1 258 1.9E-63 T 28-03-2018 CIG75_RS11105 a92c50abaf5cb919314fb96ec031f3a7 308 SUPERFAMILY SSF52540 2 225 8.65E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS11105 a92c50abaf5cb919314fb96ec031f3a7 308 SMART SM00382 26 212 2.0E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS13300 9dd45f563322dbd8ef5cb53be18e8395 2403 SUPERFAMILY SSF52777 1246 1515 2.89E-61 T 28-03-2018 CIG75_RS13300 9dd45f563322dbd8ef5cb53be18e8395 2403 Gene3D G3DSA:3.40.50.1820 2124 2383 4.3E-25 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS13300 9dd45f563322dbd8ef5cb53be18e8395 2403 Gene3D G3DSA:2.30.38.10 1855 1936 1.5E-23 T 28-03-2018 CIG75_RS13300 9dd45f563322dbd8ef5cb53be18e8395 2403 Gene3D G3DSA:1.10.1200.10 981 1042 6.3E-22 T 28-03-2018 CIG75_RS13300 9dd45f563322dbd8ef5cb53be18e8395 2403 Gene3D G3DSA:1.10.1200.10 2057 2123 4.5E-23 T 28-03-2018 CIG75_RS13300 9dd45f563322dbd8ef5cb53be18e8395 2403 SMART SM00823 Phosphopantetheine attachment site 975 1044 4.1E-4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS13300 9dd45f563322dbd8ef5cb53be18e8395 2403 SMART SM00823 Phosphopantetheine attachment site 2054 2120 6.1E-7 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS13300 9dd45f563322dbd8ef5cb53be18e8395 2403 Gene3D G3DSA:2.30.38.10 777 860 3.9E-25 T 28-03-2018 CIG75_RS13300 9dd45f563322dbd8ef5cb53be18e8395 2403 Gene3D G3DSA:3.30.559.10 2 192 4.8E-25 T 28-03-2018 CIG75_RS13300 9dd45f563322dbd8ef5cb53be18e8395 2403 SUPERFAMILY SSF52777 11 185 1.67E-36 T 28-03-2018 CIG75_RS13300 9dd45f563322dbd8ef5cb53be18e8395 2403 SUPERFAMILY SSF56801 428 987 7.46E-164 T 28-03-2018 CIG75_RS13300 9dd45f563322dbd8ef5cb53be18e8395 2403 ProSitePatterns PS00455 Putative AMP-binding domain signature. 615 626 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS13300 9dd45f563322dbd8ef5cb53be18e8395 2403 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1678 1689 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS13300 9dd45f563322dbd8ef5cb53be18e8395 2403 Pfam PF00501 AMP-binding enzyme 465 867 7.7E-108 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS13300 9dd45f563322dbd8ef5cb53be18e8395 2403 Pfam PF00501 AMP-binding enzyme 1528 1943 1.9E-104 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS13300 9dd45f563322dbd8ef5cb53be18e8395 2403 Pfam PF13193 AMP-binding enzyme C-terminal domain 875 950 2.9E-12 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS13300 9dd45f563322dbd8ef5cb53be18e8395 2403 Pfam PF13193 AMP-binding enzyme C-terminal domain 1951 2026 3.9E-16 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS13300 9dd45f563322dbd8ef5cb53be18e8395 2403 Gene3D G3DSA:3.30.559.10 1043 1264 2.7E-43 T 28-03-2018 CIG75_RS13300 9dd45f563322dbd8ef5cb53be18e8395 2403 SMART SM00824 Thioesterase 2141 2294 0.0034 T 28-03-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 CIG75_RS13300 9dd45f563322dbd8ef5cb53be18e8395 2403 Pfam PF00668 Condensation domain 1057 1509 2.0E-96 T 28-03-2018 IPR001242 Condensation domain CIG75_RS13300 9dd45f563322dbd8ef5cb53be18e8395 2403 Pfam PF00668 Condensation domain 10 445 9.4E-75 T 28-03-2018 IPR001242 Condensation domain CIG75_RS13300 9dd45f563322dbd8ef5cb53be18e8395 2403 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1549 1967 2.4E-138 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS13300 9dd45f563322dbd8ef5cb53be18e8395 2403 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 486 891 1.3E-133 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS13300 9dd45f563322dbd8ef5cb53be18e8395 2403 Gene3D G3DSA:3.40.50.980 1520 1683 8.4E-48 T 28-03-2018 CIG75_RS13300 9dd45f563322dbd8ef5cb53be18e8395 2403 Gene3D G3DSA:3.40.50.980 456 620 2.0E-46 T 28-03-2018 CIG75_RS13300 9dd45f563322dbd8ef5cb53be18e8395 2403 Pfam PF00975 Thioesterase domain 2139 2243 9.1E-29 T 28-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CIG75_RS13300 9dd45f563322dbd8ef5cb53be18e8395 2403 SUPERFAMILY SSF53474 2119 2382 2.1E-57 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS13300 9dd45f563322dbd8ef5cb53be18e8395 2403 SUPERFAMILY SSF52777 192 452 1.33E-40 T 28-03-2018 CIG75_RS13300 9dd45f563322dbd8ef5cb53be18e8395 2403 SUPERFAMILY SSF56801 1488 2063 6.93E-167 T 28-03-2018 CIG75_RS13300 9dd45f563322dbd8ef5cb53be18e8395 2403 SUPERFAMILY SSF47336 969 1041 8.9E-19 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS13300 9dd45f563322dbd8ef5cb53be18e8395 2403 Gene3D G3DSA:3.30.300.30 1938 2056 2.2E-40 T 28-03-2018 CIG75_RS13300 9dd45f563322dbd8ef5cb53be18e8395 2403 Gene3D G3DSA:3.30.300.30 862 980 6.3E-39 T 28-03-2018 CIG75_RS13300 9dd45f563322dbd8ef5cb53be18e8395 2403 SUPERFAMILY SSF52777 1061 1233 2.11E-46 T 28-03-2018 CIG75_RS13300 9dd45f563322dbd8ef5cb53be18e8395 2403 Gene3D G3DSA:3.40.50.980 1684 1850 7.6E-40 T 28-03-2018 CIG75_RS13300 9dd45f563322dbd8ef5cb53be18e8395 2403 Gene3D G3DSA:3.40.50.980 621 772 1.1E-37 T 28-03-2018 CIG75_RS13300 9dd45f563322dbd8ef5cb53be18e8395 2403 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2075 2090 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS13300 9dd45f563322dbd8ef5cb53be18e8395 2403 SUPERFAMILY SSF47336 2045 2116 1.44E-19 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS13300 9dd45f563322dbd8ef5cb53be18e8395 2403 Pfam PF00550 Phosphopantetheine attachment site 978 1039 1.7E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS13300 9dd45f563322dbd8ef5cb53be18e8395 2403 Pfam PF00550 Phosphopantetheine attachment site 2054 2116 5.5E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS09410 2740e615acb9f911aceebd91d454b3e6 347 Gene3D G3DSA:3.40.50.720 1 180 2.4E-40 T 28-03-2018 CIG75_RS09410 2740e615acb9f911aceebd91d454b3e6 347 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 5 162 1.5E-47 T 28-03-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CIG75_RS09410 2740e615acb9f911aceebd91d454b3e6 347 Gene3D G3DSA:1.10.1040.10 182 332 9.6E-56 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CIG75_RS09410 2740e615acb9f911aceebd91d454b3e6 347 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 135 155 2.9E-41 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CIG75_RS09410 2740e615acb9f911aceebd91d454b3e6 347 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 57 84 2.9E-41 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CIG75_RS09410 2740e615acb9f911aceebd91d454b3e6 347 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 175 199 2.9E-41 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CIG75_RS09410 2740e615acb9f911aceebd91d454b3e6 347 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 7 24 2.9E-41 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CIG75_RS09410 2740e615acb9f911aceebd91d454b3e6 347 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 200 224 2.9E-41 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CIG75_RS09410 2740e615acb9f911aceebd91d454b3e6 347 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 240 257 2.9E-41 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CIG75_RS09410 2740e615acb9f911aceebd91d454b3e6 347 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 3 324 36.924 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CIG75_RS09410 2740e615acb9f911aceebd91d454b3e6 347 SUPERFAMILY SSF48179 182 333 4.08E-57 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CIG75_RS09410 2740e615acb9f911aceebd91d454b3e6 347 SUPERFAMILY SSF51735 4 180 2.39E-51 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS09410 2740e615acb9f911aceebd91d454b3e6 347 PIRSF PIRSF000114 1 334 1.3E-98 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CIG75_RS09410 2740e615acb9f911aceebd91d454b3e6 347 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 182 322 6.3E-54 T 28-03-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CIG75_RS09410 2740e615acb9f911aceebd91d454b3e6 347 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 190 211 - T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CIG75_RS00810 7081284484ea02a8413108c4e7b57632 71 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 6 66 1.3E-23 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS00810 7081284484ea02a8413108c4e7b57632 71 SUPERFAMILY SSF47413 1 66 7.32E-19 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CIG75_RS00810 7081284484ea02a8413108c4e7b57632 71 Gene3D G3DSA:1.10.260.40 2 71 6.9E-11 T 28-03-2018 CIG75_RS00810 7081284484ea02a8413108c4e7b57632 71 SMART SM00530 6 62 4.3E-7 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS09295 b4dd122be977cd2a6081918e452bdc4f 385 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 187 201 - T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CIG75_RS09295 b4dd122be977cd2a6081918e452bdc4f 385 SUPERFAMILY SSF53383 18 377 4.26E-114 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CIG75_RS09295 b4dd122be977cd2a6081918e452bdc4f 385 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 4 376 1.4E-147 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CIG75_RS09295 b4dd122be977cd2a6081918e452bdc4f 385 Gene3D G3DSA:3.90.1150.10 246 382 2.9E-45 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CIG75_RS09295 b4dd122be977cd2a6081918e452bdc4f 385 PIRSF PIRSF001434 1 380 2.3E-143 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CIG75_RS09295 b4dd122be977cd2a6081918e452bdc4f 385 Gene3D G3DSA:3.40.640.10 1 245 6.7E-57 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CIG75_RS12475 00ef8ce1c17e22cc9d0b9bae8654998c 216 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 32 46 - T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CIG75_RS12475 00ef8ce1c17e22cc9d0b9bae8654998c 216 Pfam PF00834 Ribulose-phosphate 3 epimerase family 4 202 6.9E-89 T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CIG75_RS12475 00ef8ce1c17e22cc9d0b9bae8654998c 216 PIRSF PIRSF001461 1 216 2.7E-97 T 28-03-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CIG75_RS12475 00ef8ce1c17e22cc9d0b9bae8654998c 216 SUPERFAMILY SSF51366 1 215 4.1E-74 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CIG75_RS12475 00ef8ce1c17e22cc9d0b9bae8654998c 216 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 134 156 - T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CIG75_RS12475 00ef8ce1c17e22cc9d0b9bae8654998c 216 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 4 215 1.3E-95 T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CIG75_RS12475 00ef8ce1c17e22cc9d0b9bae8654998c 216 Gene3D G3DSA:3.20.20.70 1 216 1.1E-88 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CIG75_RS06865 fb6bc15b06f71fe97423d421808a2426 609 Gene3D G3DSA:3.30.930.10 341 593 3.3E-53 T 28-03-2018 CIG75_RS06865 fb6bc15b06f71fe97423d421808a2426 609 SUPERFAMILY SSF55261 300 426 6.87E-46 T 28-03-2018 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 CIG75_RS06865 fb6bc15b06f71fe97423d421808a2426 609 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 9 589 1.8E-247 T 28-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 CIG75_RS06865 fb6bc15b06f71fe97423d421808a2426 609 SUPERFAMILY SSF55681 119 303 5.18E-107 T 28-03-2018 CIG75_RS06865 fb6bc15b06f71fe97423d421808a2426 609 SUPERFAMILY SSF55681 431 590 5.18E-107 T 28-03-2018 CIG75_RS06865 fb6bc15b06f71fe97423d421808a2426 609 Pfam PF00152 tRNA synthetases class II (D, K and N) 128 565 3.4E-109 T 28-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CIG75_RS06865 fb6bc15b06f71fe97423d421808a2426 609 Pfam PF01336 OB-fold nucleic acid binding domain 25 111 1.8E-14 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CIG75_RS06865 fb6bc15b06f71fe97423d421808a2426 609 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 8 591 34.518 T 28-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 CIG75_RS06865 fb6bc15b06f71fe97423d421808a2426 609 Pfam PF02938 GAD domain 319 412 1.7E-31 T 28-03-2018 IPR029351 GAD domain Reactome: R-HSA-379726 CIG75_RS06865 fb6bc15b06f71fe97423d421808a2426 609 PRINTS PR01042 Aspartyl-tRNA synthetase signature 218 231 1.4E-26 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CIG75_RS06865 fb6bc15b06f71fe97423d421808a2426 609 PRINTS PR01042 Aspartyl-tRNA synthetase signature 481 497 1.4E-26 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CIG75_RS06865 fb6bc15b06f71fe97423d421808a2426 609 PRINTS PR01042 Aspartyl-tRNA synthetase signature 201 213 1.4E-26 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CIG75_RS06865 fb6bc15b06f71fe97423d421808a2426 609 PRINTS PR01042 Aspartyl-tRNA synthetase signature 525 539 1.4E-26 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CIG75_RS06865 fb6bc15b06f71fe97423d421808a2426 609 Gene3D G3DSA:3.30.930.10 109 331 1.5E-49 T 28-03-2018 CIG75_RS06865 fb6bc15b06f71fe97423d421808a2426 609 Gene3D G3DSA:2.40.50.140 1 108 4.3E-27 T 28-03-2018 CIG75_RS06865 fb6bc15b06f71fe97423d421808a2426 609 SUPERFAMILY SSF50249 6 118 3.24E-30 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CIG75_RS00340 d15851fe88c8103df91c4153c185b9f6 670 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 5 58 2.9E-17 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CIG75_RS00340 d15851fe88c8103df91c4153c185b9f6 670 Gene3D G3DSA:3.40.228.10 161 252 2.6E-21 T 28-03-2018 CIG75_RS00340 d15851fe88c8103df91c4153c185b9f6 670 Gene3D G3DSA:2.40.40.20 531 670 4.9E-24 T 28-03-2018 CIG75_RS00340 d15851fe88c8103df91c4153c185b9f6 670 SMART SM00926 3 58 1.2E-23 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CIG75_RS00340 d15851fe88c8103df91c4153c185b9f6 670 SUPERFAMILY SSF50692 515 670 1.85E-28 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain CIG75_RS00340 d15851fe88c8103df91c4153c185b9f6 670 Gene3D G3DSA:3.40.50.740 62 160 8.2E-12 T 28-03-2018 CIG75_RS00340 d15851fe88c8103df91c4153c185b9f6 670 SUPERFAMILY SSF53706 5 562 5.5E-157 T 28-03-2018 CIG75_RS00340 d15851fe88c8103df91c4153c185b9f6 670 Pfam PF01568 Molydopterin dinucleotide binding domain 561 656 7.5E-15 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CIG75_RS00340 d15851fe88c8103df91c4153c185b9f6 670 Gene3D G3DSA:2.20.25.90 1 61 1.1E-20 T 28-03-2018 CIG75_RS00340 d15851fe88c8103df91c4153c185b9f6 670 Gene3D G3DSA:3.40.50.740 253 514 5.3E-44 T 28-03-2018 CIG75_RS00340 d15851fe88c8103df91c4153c185b9f6 670 Pfam PF00384 Molybdopterin oxidoreductase 61 463 1.6E-56 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CIG75_RS15930 3cb976ab529a532e4b5cc6c8ea6018b8 234 Pfam PF06508 Queuosine biosynthesis protein QueC 4 215 4.8E-73 T 28-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 CIG75_RS15930 3cb976ab529a532e4b5cc6c8ea6018b8 234 PIRSF PIRSF006293 1 227 1.1E-76 T 28-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 CIG75_RS15930 3cb976ab529a532e4b5cc6c8ea6018b8 234 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 5 208 1.2E-62 T 28-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 CIG75_RS15930 3cb976ab529a532e4b5cc6c8ea6018b8 234 Gene3D G3DSA:3.40.50.620 2 232 1.1E-45 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CIG75_RS15930 3cb976ab529a532e4b5cc6c8ea6018b8 234 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 3 221 54.06 T 28-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 CIG75_RS15930 3cb976ab529a532e4b5cc6c8ea6018b8 234 SUPERFAMILY SSF52402 3 226 4.63E-57 T 28-03-2018 CIG75_RS15280 3532e19f09684455ce08c5edac22eb09 109 Pfam PF08827 Domain of unknown function (DUF1805) 37 97 5.3E-22 T 28-03-2018 IPR014931 Protein of unknown function DUF1805 CIG75_RS15280 3532e19f09684455ce08c5edac22eb09 109 SUPERFAMILY SSF102891 1 99 6.67E-29 T 28-03-2018 IPR014931 Protein of unknown function DUF1805 CIG75_RS15280 3532e19f09684455ce08c5edac22eb09 109 Gene3D G3DSA:3.30.1980.10 1 99 2.5E-34 T 28-03-2018 CIG75_RS12300 9bdcbf92f4769227e927d47616648a33 169 Gene3D G3DSA:2.40.30.60 1 90 4.9E-21 T 28-03-2018 IPR002676 RimM protein GO:0006364 CIG75_RS12300 9bdcbf92f4769227e927d47616648a33 169 Gene3D G3DSA:2.30.30.240 94 162 1.3E-18 T 28-03-2018 CIG75_RS12300 9bdcbf92f4769227e927d47616648a33 169 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 1 167 22.153 T 28-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 CIG75_RS12300 9bdcbf92f4769227e927d47616648a33 169 SUPERFAMILY SSF50346 97 167 2.94E-19 T 28-03-2018 IPR011033 PRC-barrel-like CIG75_RS12300 9bdcbf92f4769227e927d47616648a33 169 Pfam PF05239 PRC-barrel domain 95 167 1.5E-11 T 28-03-2018 IPR027275 PRC-barrel domain CIG75_RS12300 9bdcbf92f4769227e927d47616648a33 169 SUPERFAMILY SSF50447 1 89 1.2E-17 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CIG75_RS12300 9bdcbf92f4769227e927d47616648a33 169 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 1 166 3.3E-45 T 28-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 CIG75_RS12300 9bdcbf92f4769227e927d47616648a33 169 Pfam PF01782 RimM N-terminal domain 4 86 2.7E-19 T 28-03-2018 IPR002676 RimM protein GO:0006364 CIG75_RS13295 c085140c142eed5f34dafef9c4df94dc 75 SUPERFAMILY SSF160582 1 65 8.11E-26 T 28-03-2018 CIG75_RS13295 c085140c142eed5f34dafef9c4df94dc 75 Gene3D G3DSA:3.90.820.10 2 67 5.1E-28 T 28-03-2018 CIG75_RS13295 c085140c142eed5f34dafef9c4df94dc 75 Pfam PF03621 MbtH-like protein 1 52 5.0E-24 T 28-03-2018 IPR005153 MbtH-like protein CIG75_RS13295 c085140c142eed5f34dafef9c4df94dc 75 SMART SM00923 3 53 2.5E-24 T 28-03-2018 IPR005153 MbtH-like protein CIG75_RS11160 c2d9d05a3214c8f94d21ee9f35b01af4 953 SUPERFAMILY SSF55073 693 868 4.4E-28 T 28-03-2018 IPR029787 Nucleotide cyclase CIG75_RS11160 c2d9d05a3214c8f94d21ee9f35b01af4 953 SUPERFAMILY SSF158472 613 657 8.24E-7 T 28-03-2018 CIG75_RS11160 c2d9d05a3214c8f94d21ee9f35b01af4 953 Gene3D G3DSA:3.30.70.1230 693 887 1.3E-21 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CIG75_RS11160 c2d9d05a3214c8f94d21ee9f35b01af4 953 Pfam PF00672 HAMP domain 612 657 4.7E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CIG75_RS11160 c2d9d05a3214c8f94d21ee9f35b01af4 953 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 699 867 1.7E-8 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CIG75_RS11160 c2d9d05a3214c8f94d21ee9f35b01af4 953 SMART SM00304 609 661 6.4E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CIG75_RS11160 c2d9d05a3214c8f94d21ee9f35b01af4 953 Gene3D G3DSA:2.120.10.30 32 555 1.3E-7 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CIG75_RS11160 c2d9d05a3214c8f94d21ee9f35b01af4 953 SUPERFAMILY SSF63825 252 292 5.23E-5 T 28-03-2018 CIG75_RS11160 c2d9d05a3214c8f94d21ee9f35b01af4 953 SUPERFAMILY SSF63825 41 187 5.23E-5 T 28-03-2018 CIG75_RS11160 c2d9d05a3214c8f94d21ee9f35b01af4 953 Gene3D G3DSA:1.25.40.10 888 942 4.5E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS18850 318f9373fb43f833b5533fa3dde4b87a 385 Gene3D G3DSA:3.90.1150.10 1 160 8.8E-49 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CIG75_RS18850 318f9373fb43f833b5533fa3dde4b87a 385 Gene3D G3DSA:3.90.1150.10 276 380 1.3E-19 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CIG75_RS18850 318f9373fb43f833b5533fa3dde4b87a 385 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 1 378 2.9E-150 T 28-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 CIG75_RS18850 318f9373fb43f833b5533fa3dde4b87a 385 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 205 242 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CIG75_RS18850 318f9373fb43f833b5533fa3dde4b87a 385 Pfam PF00202 Aminotransferase class-III 6 378 7.5E-118 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CIG75_RS18850 318f9373fb43f833b5533fa3dde4b87a 385 SUPERFAMILY SSF53383 2 379 2.5E-128 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CIG75_RS18850 318f9373fb43f833b5533fa3dde4b87a 385 Gene3D G3DSA:3.40.640.10 161 275 1.7E-46 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CIG75_RS18850 318f9373fb43f833b5533fa3dde4b87a 385 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 1 379 45.513 T 28-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 CIG75_RS18850 318f9373fb43f833b5533fa3dde4b87a 385 PIRSF PIRSF000521 2 146 5.3E-8 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CIG75_RS18850 318f9373fb43f833b5533fa3dde4b87a 385 PIRSF PIRSF000521 150 381 3.3E-41 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CIG75_RS20145 e661e1193038aa9edae85f20e8dcb48f 321 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS20145 e661e1193038aa9edae85f20e8dcb48f 321 Gene3D G3DSA:3.40.50.300 2 275 1.5E-59 T 28-03-2018 CIG75_RS20145 e661e1193038aa9edae85f20e8dcb48f 321 SUPERFAMILY SSF52540 4 222 5.01E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS20145 e661e1193038aa9edae85f20e8dcb48f 321 Pfam PF00005 ABC transporter 22 163 3.2E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS20145 e661e1193038aa9edae85f20e8dcb48f 321 SMART SM00382 30 211 1.5E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS07590 480e6a1a256b8e8afdbbfd38ed4f6e88 373 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 10 364 3.0E-103 T 28-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 CIG75_RS07590 480e6a1a256b8e8afdbbfd38ed4f6e88 373 Gene3D G3DSA:3.40.640.10 49 258 3.0E-43 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CIG75_RS07590 480e6a1a256b8e8afdbbfd38ed4f6e88 373 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 8 366 58.843 T 28-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 CIG75_RS07590 480e6a1a256b8e8afdbbfd38ed4f6e88 373 SUPERFAMILY SSF53383 18 365 1.39E-89 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CIG75_RS07590 480e6a1a256b8e8afdbbfd38ed4f6e88 373 Gene3D G3DSA:3.90.1150.10 259 361 2.4E-27 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CIG75_RS07590 480e6a1a256b8e8afdbbfd38ed4f6e88 373 Pfam PF00155 Aminotransferase class I and II 35 359 8.4E-63 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CIG75_RS17795 0eb5d2411b88bf50b5a0c6367ff9587f 424 Gene3D G3DSA:1.25.40.10 287 415 1.2E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS17795 0eb5d2411b88bf50b5a0c6367ff9587f 424 SUPERFAMILY SSF53098 92 276 5.18E-26 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CIG75_RS17795 0eb5d2411b88bf50b5a0c6367ff9587f 424 Gene3D G3DSA:3.30.420.10 104 286 5.0E-20 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CIG75_RS17795 0eb5d2411b88bf50b5a0c6367ff9587f 424 Pfam PF13482 RNase_H superfamily 105 271 3.7E-36 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CIG75_RS09760 40c564c01f9f3d68e9b656358a9bc289 1775 Gene3D G3DSA:2.30.38.10 376 453 1.4E-19 T 28-03-2018 CIG75_RS09760 40c564c01f9f3d68e9b656358a9bc289 1775 ProSitePatterns PS00455 Putative AMP-binding domain signature. 168 179 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS09760 40c564c01f9f3d68e9b656358a9bc289 1775 Pfam PF00668 Condensation domain 701 1158 4.7E-101 T 28-03-2018 IPR001242 Condensation domain CIG75_RS09760 40c564c01f9f3d68e9b656358a9bc289 1775 Gene3D G3DSA:1.10.1200.10 591 677 4.9E-18 T 28-03-2018 CIG75_RS09760 40c564c01f9f3d68e9b656358a9bc289 1775 Gene3D G3DSA:1.10.1200.10 1688 1760 6.1E-25 T 28-03-2018 CIG75_RS09760 40c564c01f9f3d68e9b656358a9bc289 1775 SUPERFAMILY SSF56801 10 568 1.7E-111 T 28-03-2018 CIG75_RS09760 40c564c01f9f3d68e9b656358a9bc289 1775 SUPERFAMILY SSF47336 602 696 3.4E-16 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS09760 40c564c01f9f3d68e9b656358a9bc289 1775 SUPERFAMILY SSF47336 1676 1745 5.1E-22 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS09760 40c564c01f9f3d68e9b656358a9bc289 1775 Gene3D G3DSA:3.40.50.980 8 170 1.7E-31 T 28-03-2018 CIG75_RS09760 40c564c01f9f3d68e9b656358a9bc289 1775 SUPERFAMILY SSF52777 706 879 1.33E-43 T 28-03-2018 CIG75_RS09760 40c564c01f9f3d68e9b656358a9bc289 1775 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1198 1596 1.2E-142 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS09760 40c564c01f9f3d68e9b656358a9bc289 1775 Gene3D G3DSA:3.40.50.980 171 335 6.9E-36 T 28-03-2018 CIG75_RS09760 40c564c01f9f3d68e9b656358a9bc289 1775 Pfam PF00550 Phosphopantetheine attachment site 610 673 7.2E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS09760 40c564c01f9f3d68e9b656358a9bc289 1775 Pfam PF00550 Phosphopantetheine attachment site 1684 1744 1.0E-17 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS09760 40c564c01f9f3d68e9b656358a9bc289 1775 Pfam PF13193 AMP-binding enzyme C-terminal domain 1580 1654 2.3E-12 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS09760 40c564c01f9f3d68e9b656358a9bc289 1775 Gene3D G3DSA:3.30.300.30 1567 1687 2.5E-38 T 28-03-2018 CIG75_RS09760 40c564c01f9f3d68e9b656358a9bc289 1775 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1706 1721 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS09760 40c564c01f9f3d68e9b656358a9bc289 1775 Gene3D G3DSA:3.30.300.30 454 562 1.3E-16 T 28-03-2018 CIG75_RS09760 40c564c01f9f3d68e9b656358a9bc289 1775 SUPERFAMILY SSF52777 890 1142 4.22E-59 T 28-03-2018 CIG75_RS09760 40c564c01f9f3d68e9b656358a9bc289 1775 Gene3D G3DSA:3.40.50.980 1325 1482 2.1E-43 T 28-03-2018 CIG75_RS09760 40c564c01f9f3d68e9b656358a9bc289 1775 Gene3D G3DSA:3.30.559.10 678 885 3.4E-43 T 28-03-2018 CIG75_RS09760 40c564c01f9f3d68e9b656358a9bc289 1775 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1319 1330 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS09760 40c564c01f9f3d68e9b656358a9bc289 1775 Pfam PF00501 AMP-binding enzyme 16 461 1.1E-83 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS09760 40c564c01f9f3d68e9b656358a9bc289 1775 Pfam PF00501 AMP-binding enzyme 1178 1572 1.0E-108 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS09760 40c564c01f9f3d68e9b656358a9bc289 1775 SMART SM00823 Phosphopantetheine attachment site 1682 1751 1.7E-8 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS09760 40c564c01f9f3d68e9b656358a9bc289 1775 SMART SM00823 Phosphopantetheine attachment site 607 678 6.2E-14 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS09760 40c564c01f9f3d68e9b656358a9bc289 1775 SMART SM01294 608 674 0.0045 T 28-03-2018 CIG75_RS09760 40c564c01f9f3d68e9b656358a9bc289 1775 Gene3D G3DSA:3.40.50.980 1169 1324 1.4E-48 T 28-03-2018 CIG75_RS09760 40c564c01f9f3d68e9b656358a9bc289 1775 SUPERFAMILY SSF56801 1137 1695 4.19E-170 T 28-03-2018 CIG75_RS09760 40c564c01f9f3d68e9b656358a9bc289 1775 Gene3D G3DSA:2.30.38.10 1483 1562 2.9E-25 T 28-03-2018 CIG75_RS17980 b837f0e64b96da6012afeed33084b5e1 308 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS17980 b837f0e64b96da6012afeed33084b5e1 308 SMART SM00382 31 211 7.6E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS17980 b837f0e64b96da6012afeed33084b5e1 308 Gene3D G3DSA:3.40.50.300 3 258 3.5E-61 T 28-03-2018 CIG75_RS17980 b837f0e64b96da6012afeed33084b5e1 308 Pfam PF00005 ABC transporter 23 163 7.2E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS17980 b837f0e64b96da6012afeed33084b5e1 308 SUPERFAMILY SSF52540 4 232 4.12E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS10105 6d2b2cb83987f9e49ad69eba027988a0 499 Gene3D G3DSA:3.40.50.980 163 313 2.5E-41 T 28-03-2018 CIG75_RS10105 6d2b2cb83987f9e49ad69eba027988a0 499 Gene3D G3DSA:3.30.300.30 395 498 2.3E-31 T 28-03-2018 CIG75_RS10105 6d2b2cb83987f9e49ad69eba027988a0 499 Gene3D G3DSA:3.40.50.980 6 162 7.4E-42 T 28-03-2018 CIG75_RS10105 6d2b2cb83987f9e49ad69eba027988a0 499 Pfam PF13193 AMP-binding enzyme C-terminal domain 410 485 1.0E-20 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS10105 6d2b2cb83987f9e49ad69eba027988a0 499 Pfam PF00501 AMP-binding enzyme 11 401 4.1E-103 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS10105 6d2b2cb83987f9e49ad69eba027988a0 499 ProSitePatterns PS00455 Putative AMP-binding domain signature. 156 167 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS10105 6d2b2cb83987f9e49ad69eba027988a0 499 SUPERFAMILY SSF56801 8 495 6.02E-156 T 28-03-2018 CIG75_RS10105 6d2b2cb83987f9e49ad69eba027988a0 499 Gene3D G3DSA:2.30.38.10 314 394 1.5E-28 T 28-03-2018 CIG75_RS06950 2b01944a1850b01340293e4f98cb124d 289 TIGRFAM TIGR01475 ubiA_other: putative 4-hydroxybenzoate polyprenyltransferase 3 284 4.3E-98 T 28-03-2018 IPR006371 4-hydroxybenzoate polyprenyltransferase-related CIG75_RS06950 2b01944a1850b01340293e4f98cb124d 289 Pfam PF01040 UbiA prenyltransferase family 27 270 1.5E-56 T 28-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 CIG75_RS15405 39ba06c265f0c5e31fa3521427c72910 378 Gene3D G3DSA:3.40.50.2000 181 354 4.8E-46 T 28-03-2018 CIG75_RS15405 39ba06c265f0c5e31fa3521427c72910 378 Pfam PF00534 Glycosyl transferases group 1 192 338 6.4E-34 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CIG75_RS15405 39ba06c265f0c5e31fa3521427c72910 378 Gene3D G3DSA:3.40.50.2000 2 180 2.6E-28 T 28-03-2018 CIG75_RS15405 39ba06c265f0c5e31fa3521427c72910 378 Pfam PF13579 Glycosyl transferase 4-like domain 15 172 4.9E-29 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CIG75_RS15405 39ba06c265f0c5e31fa3521427c72910 378 SUPERFAMILY SSF53756 11 369 4.0E-87 T 28-03-2018 CIG75_RS05950 b3db8dbfb047635d41a3c78054743d05 240 SUPERFAMILY SSF47090 49 114 3.92E-17 T 28-03-2018 IPR002477 Peptidoglycan binding-like CIG75_RS05950 b3db8dbfb047635d41a3c78054743d05 240 Pfam PF01471 Putative peptidoglycan binding domain 58 110 3.8E-14 T 28-03-2018 IPR002477 Peptidoglycan binding-like CIG75_RS05950 b3db8dbfb047635d41a3c78054743d05 240 Pfam PF00877 NlpC/P60 family 133 238 5.9E-28 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CIG75_RS05950 b3db8dbfb047635d41a3c78054743d05 240 Gene3D G3DSA:1.10.101.10 46 116 2.0E-18 T 28-03-2018 IPR002477 Peptidoglycan binding-like CIG75_RS05950 b3db8dbfb047635d41a3c78054743d05 240 Gene3D G3DSA:3.90.1720.10 117 240 3.2E-37 T 28-03-2018 CIG75_RS05950 b3db8dbfb047635d41a3c78054743d05 240 SUPERFAMILY SSF54001 118 239 3.48E-39 T 28-03-2018 CIG75_RS03645 78005ed555877089fe42f905a33fe3c2 97 TIGRFAM TIGR02531 yecD_yerC: TrpR homolog YerC/YecD 7 94 3.3E-47 T 28-03-2018 IPR013368 TrpR homologue YerC/YecD CIG75_RS03645 78005ed555877089fe42f905a33fe3c2 97 Gene3D G3DSA:1.10.1270.10 1 97 2.9E-31 T 28-03-2018 CIG75_RS03645 78005ed555877089fe42f905a33fe3c2 97 SUPERFAMILY SSF48295 3 94 4.34E-32 T 28-03-2018 IPR010921 Trp repressor/replication initiator GO:0043565 CIG75_RS03645 78005ed555877089fe42f905a33fe3c2 97 Pfam PF01371 Trp repressor protein 10 94 5.5E-33 T 28-03-2018 IPR000831 Trp repressor GO:0003700|GO:0005622|GO:0006355 CIG75_RS03645 78005ed555877089fe42f905a33fe3c2 97 PIRSF PIRSF012508 1 97 1.1E-47 T 28-03-2018 IPR013368 TrpR homologue YerC/YecD CIG75_RS18775 c7f38acb03a71048f272a45da49903c1 324 Gene3D G3DSA:3.40.980.10 135 313 2.0E-38 T 28-03-2018 IPR001453 MoaB/Mog domain CIG75_RS18775 c7f38acb03a71048f272a45da49903c1 324 SMART SM00852 174 306 6.3E-24 T 28-03-2018 IPR001453 MoaB/Mog domain CIG75_RS18775 c7f38acb03a71048f272a45da49903c1 324 SUPERFAMILY SSF53218 170 318 7.46E-34 T 28-03-2018 IPR001453 MoaB/Mog domain CIG75_RS18775 c7f38acb03a71048f272a45da49903c1 324 Pfam PF00994 Probable molybdopterin binding domain 174 288 8.6E-23 T 28-03-2018 IPR001453 MoaB/Mog domain CIG75_RS19615 021ae508e4ff6c3bb0f752c1d29c3d1d 72 Gene3D G3DSA:2.40.50.140 1 72 7.9E-39 T 28-03-2018 CIG75_RS19615 021ae508e4ff6c3bb0f752c1d29c3d1d 72 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 71 5.2E-40 T 28-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 CIG75_RS19615 021ae508e4ff6c3bb0f752c1d29c3d1d 72 SUPERFAMILY SSF50249 2 71 5.63E-29 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CIG75_RS19615 021ae508e4ff6c3bb0f752c1d29c3d1d 72 SMART SM00316 2 72 4.0E-5 T 28-03-2018 IPR022967 RNA-binding domain, S1 CIG75_RS19615 021ae508e4ff6c3bb0f752c1d29c3d1d 72 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 28.367 T 28-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 CIG75_RS19615 021ae508e4ff6c3bb0f752c1d29c3d1d 72 Pfam PF01176 Translation initiation factor 1A / IF-1 7 70 9.5E-30 T 28-03-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 CIG75_RS11745 70010430ecb998361682bd50c77e4efc 413 Pfam PF00675 Insulinase (Peptidase family M16) 11 158 1.6E-42 T 28-03-2018 IPR011765 Peptidase M16, N-terminal CIG75_RS11745 70010430ecb998361682bd50c77e4efc 413 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 32 55 - T 28-03-2018 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 CIG75_RS11745 70010430ecb998361682bd50c77e4efc 413 Gene3D G3DSA:3.30.830.10 233 409 1.7E-45 T 28-03-2018 CIG75_RS11745 70010430ecb998361682bd50c77e4efc 413 Gene3D G3DSA:3.30.830.10 1 220 1.7E-59 T 28-03-2018 CIG75_RS11745 70010430ecb998361682bd50c77e4efc 413 SUPERFAMILY SSF63411 227 406 1.31E-48 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CIG75_RS11745 70010430ecb998361682bd50c77e4efc 413 SUPERFAMILY SSF63411 2 211 6.17E-60 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CIG75_RS11745 70010430ecb998361682bd50c77e4efc 413 Pfam PF05193 Peptidase M16 inactive domain 167 337 8.2E-40 T 28-03-2018 IPR007863 Peptidase M16, C-terminal CIG75_RS01135 503d0e23cf33b5cbb4eb5b901b44da9c 518 SMART SM00382 348 514 1.6E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS01135 503d0e23cf33b5cbb4eb5b901b44da9c 518 SMART SM00382 28 251 1.2E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS01135 503d0e23cf33b5cbb4eb5b901b44da9c 518 Pfam PF00005 ABC transporter 21 190 3.1E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS01135 503d0e23cf33b5cbb4eb5b901b44da9c 518 Pfam PF00005 ABC transporter 341 468 1.4E-20 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS01135 503d0e23cf33b5cbb4eb5b901b44da9c 518 Gene3D G3DSA:3.40.50.300 293 513 4.5E-37 T 28-03-2018 CIG75_RS01135 503d0e23cf33b5cbb4eb5b901b44da9c 518 Pfam PF12848 ABC transporter 229 314 5.1E-25 T 28-03-2018 IPR032781 ABC-transporter extension domain CIG75_RS01135 503d0e23cf33b5cbb4eb5b901b44da9c 518 Gene3D G3DSA:3.40.50.300 1 292 7.2E-54 T 28-03-2018 CIG75_RS01135 503d0e23cf33b5cbb4eb5b901b44da9c 518 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS01135 503d0e23cf33b5cbb4eb5b901b44da9c 518 SUPERFAMILY SSF52540 309 509 1.5E-35 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS01135 503d0e23cf33b5cbb4eb5b901b44da9c 518 SUPERFAMILY SSF52540 5 244 2.62E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS11815 81f394910ebacb701d4b0e0d1cdd41f9 379 Gene3D G3DSA:2.40.50.140 136 197 4.0E-16 T 28-03-2018 CIG75_RS11815 81f394910ebacb701d4b0e0d1cdd41f9 379 SUPERFAMILY SSF54814 199 277 3.2E-31 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CIG75_RS11815 81f394910ebacb701d4b0e0d1cdd41f9 379 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 4 342 3.0E-132 T 28-03-2018 IPR010213 Transcription termination factor NusA GO:0003723 CIG75_RS11815 81f394910ebacb701d4b0e0d1cdd41f9 379 SMART SM00316 133 199 9.6E-12 T 28-03-2018 IPR022967 RNA-binding domain, S1 CIG75_RS11815 81f394910ebacb701d4b0e0d1cdd41f9 379 Pfam PF00575 S1 RNA binding domain 136 193 5.3E-9 T 28-03-2018 IPR003029 S1 domain GO:0003676 CIG75_RS11815 81f394910ebacb701d4b0e0d1cdd41f9 379 SUPERFAMILY SSF54814 278 341 2.29E-16 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CIG75_RS11815 81f394910ebacb701d4b0e0d1cdd41f9 379 SUPERFAMILY SSF50249 132 198 3.82E-19 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CIG75_RS11815 81f394910ebacb701d4b0e0d1cdd41f9 379 SMART SM00322 229 292 0.72 T 28-03-2018 IPR004087 K Homology domain GO:0003676 CIG75_RS11815 81f394910ebacb701d4b0e0d1cdd41f9 379 SMART SM00322 300 374 0.44 T 28-03-2018 IPR004087 K Homology domain GO:0003676 CIG75_RS11815 81f394910ebacb701d4b0e0d1cdd41f9 379 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 2 379 29.975 T 28-03-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 CIG75_RS11815 81f394910ebacb701d4b0e0d1cdd41f9 379 Gene3D G3DSA:3.30.300.20 273 341 2.9E-17 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CIG75_RS11815 81f394910ebacb701d4b0e0d1cdd41f9 379 SUPERFAMILY SSF69705 1 126 8.37E-44 T 28-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CIG75_RS11815 81f394910ebacb701d4b0e0d1cdd41f9 379 Pfam PF08529 NusA N-terminal domain 4 123 2.8E-45 T 28-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CIG75_RS11815 81f394910ebacb701d4b0e0d1cdd41f9 379 Gene3D G3DSA:3.30.1480.10 1 129 1.1E-51 T 28-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CIG75_RS11815 81f394910ebacb701d4b0e0d1cdd41f9 379 Pfam PF13184 NusA-like KH domain 229 296 1.1E-29 T 28-03-2018 IPR025249 KH domain, NusA-like GO:0003723 CIG75_RS11815 81f394910ebacb701d4b0e0d1cdd41f9 379 Gene3D G3DSA:3.30.300.20 198 272 5.4E-35 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CIG75_RS19690 e0e873437b7b349772e8cd4f4b7afb6f 87 ProSitePatterns PS00056 Ribosomal protein S17 signature. 58 70 - T 28-03-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CIG75_RS19690 e0e873437b7b349772e8cd4f4b7afb6f 87 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 7 78 2.7E-36 T 28-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS19690 e0e873437b7b349772e8cd4f4b7afb6f 87 SUPERFAMILY SSF50249 7 84 7.28E-31 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CIG75_RS19690 e0e873437b7b349772e8cd4f4b7afb6f 87 Pfam PF00366 Ribosomal protein S17 12 79 1.4E-32 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS19690 e0e873437b7b349772e8cd4f4b7afb6f 87 Gene3D G3DSA:2.40.50.140 7 84 2.1E-30 T 28-03-2018 CIG75_RS19690 e0e873437b7b349772e8cd4f4b7afb6f 87 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 7 82 25.453 T 28-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS19690 e0e873437b7b349772e8cd4f4b7afb6f 87 PRINTS PR00973 Ribosomal protein S17 family signature 68 75 2.7E-11 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS19690 e0e873437b7b349772e8cd4f4b7afb6f 87 PRINTS PR00973 Ribosomal protein S17 family signature 26 49 2.7E-11 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS19690 e0e873437b7b349772e8cd4f4b7afb6f 87 PRINTS PR00973 Ribosomal protein S17 family signature 58 68 2.7E-11 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS19690 e0e873437b7b349772e8cd4f4b7afb6f 87 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 7 78 2.0E-25 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS00490 e825cbe568278d0763166a418f5d4bbb 370 Pfam PF07833 Copper amine oxidase N-terminal domain 51 134 3.0E-18 T 28-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CIG75_RS00490 e825cbe568278d0763166a418f5d4bbb 370 Gene3D G3DSA:3.30.457.10 64 131 1.1E-16 T 28-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CIG75_RS00490 e825cbe568278d0763166a418f5d4bbb 370 Gene3D G3DSA:3.30.457.10 12 63 1.4E-7 T 28-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CIG75_RS00490 e825cbe568278d0763166a418f5d4bbb 370 SUPERFAMILY SSF55383 54 135 5.23E-15 T 28-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CIG75_RS00490 e825cbe568278d0763166a418f5d4bbb 370 Gene3D G3DSA:3.20.20.370 161 359 8.0E-46 T 28-03-2018 CIG75_RS00490 e825cbe568278d0763166a418f5d4bbb 370 SUPERFAMILY SSF88713 165 355 1.01E-48 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CIG75_RS00490 e825cbe568278d0763166a418f5d4bbb 370 Pfam PF01522 Polysaccharide deacetylase 167 291 2.7E-29 T 28-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CIG75_RS02795 a1bc499e0eb68561155428343422d714 1574 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 38 297 5.3E-59 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CIG75_RS02795 a1bc499e0eb68561155428343422d714 1574 SUPERFAMILY SSF53901 187 416 4.36E-81 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS02795 a1bc499e0eb68561155428343422d714 1574 SUPERFAMILY SSF53901 35 159 4.36E-81 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS02795 a1bc499e0eb68561155428343422d714 1574 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 425 535 9.4E-18 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS02795 a1bc499e0eb68561155428343422d714 1574 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 204 220 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CIG75_RS02795 a1bc499e0eb68561155428343422d714 1574 Pfam PF14765 Polyketide synthase dehydratase 670 947 3.5E-40 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS02795 a1bc499e0eb68561155428343422d714 1574 Pfam PF08659 KR domain 1171 1366 1.4E-48 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS02795 a1bc499e0eb68561155428343422d714 1574 Gene3D G3DSA:3.10.129.10 677 791 3.0E-10 T 28-03-2018 CIG75_RS02795 a1bc499e0eb68561155428343422d714 1574 SMART SM00825 Beta-ketoacyl synthase 39 476 4.8E-143 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CIG75_RS02795 a1bc499e0eb68561155428343422d714 1574 Gene3D G3DSA:3.40.47.10 313 478 2.6E-53 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS02795 a1bc499e0eb68561155428343422d714 1574 Pfam PF00550 Phosphopantetheine attachment site 1456 1518 1.2E-6 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS02795 a1bc499e0eb68561155428343422d714 1574 SUPERFAMILY SSF47336 1449 1518 1.44E-9 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS02795 a1bc499e0eb68561155428343422d714 1574 Gene3D G3DSA:3.40.50.720 1162 1462 5.8E-34 T 28-03-2018 CIG75_RS02795 a1bc499e0eb68561155428343422d714 1574 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 306 422 1.3E-38 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CIG75_RS02795 a1bc499e0eb68561155428343422d714 1574 SUPERFAMILY SSF51735 1170 1408 3.24E-31 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS02795 a1bc499e0eb68561155428343422d714 1574 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1171 1367 6.8E-43 T 28-03-2018 CIG75_RS02795 a1bc499e0eb68561155428343422d714 1574 SMART SM00826 670 822 6.7E-14 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS02795 a1bc499e0eb68561155428343422d714 1574 Gene3D G3DSA:1.10.1200.10 1463 1527 4.0E-11 T 28-03-2018 CIG75_RS02795 a1bc499e0eb68561155428343422d714 1574 Gene3D G3DSA:3.40.47.10 30 309 6.1E-66 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS02795 a1bc499e0eb68561155428343422d714 1574 SUPERFAMILY SSF51735 958 1159 1.02E-13 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS00985 f208f72548dbd75d0f892b5678fa9758 364 SUPERFAMILY SSF56281 94 329 4.32E-38 T 28-03-2018 IPR001279 Metallo-beta-lactamase CIG75_RS00985 f208f72548dbd75d0f892b5678fa9758 364 Gene3D G3DSA:3.60.15.10 63 362 1.2E-49 T 28-03-2018 IPR001279 Metallo-beta-lactamase CIG75_RS00985 f208f72548dbd75d0f892b5678fa9758 364 PIRSF PIRSF038896 12 355 1.9E-95 T 28-03-2018 IPR024884 N-acyl-phosphatidylethanolamine-hydrolysing phospholipase D GO:0008270|GO:0070290 Reactome: R-HSA-2466712 CIG75_RS00985 f208f72548dbd75d0f892b5678fa9758 364 Pfam PF12706 Beta-lactamase superfamily domain 118 313 1.7E-45 T 28-03-2018 IPR001279 Metallo-beta-lactamase CIG75_RS09905 06a7a76f095b44a4ff44437e11b60423 126 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 1 119 5.8E-60 T 28-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CIG75_RS09905 06a7a76f095b44a4ff44437e11b60423 126 Pfam PF02261 Aspartate decarboxylase 1 114 2.3E-55 T 28-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CIG75_RS09905 06a7a76f095b44a4ff44437e11b60423 126 Gene3D G3DSA:2.40.40.20 1 117 3.1E-57 T 28-03-2018 CIG75_RS09905 06a7a76f095b44a4ff44437e11b60423 126 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 5 98 2.0E-39 T 28-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CIG75_RS09905 06a7a76f095b44a4ff44437e11b60423 126 PIRSF PIRSF006246 1 125 2.5E-57 T 28-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CIG75_RS09905 06a7a76f095b44a4ff44437e11b60423 126 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 126 74.973 T 28-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CIG75_RS09905 06a7a76f095b44a4ff44437e11b60423 126 SUPERFAMILY SSF50692 1 117 4.47E-52 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain CIG75_RS09785 9e96a118f49c91f5fa7b63c10705381f 1792 SUPERFAMILY SSF52777 902 1153 9.23E-59 T 28-03-2018 CIG75_RS09785 9e96a118f49c91f5fa7b63c10705381f 1792 Gene3D G3DSA:3.40.50.980 181 345 2.2E-34 T 28-03-2018 CIG75_RS09785 9e96a118f49c91f5fa7b63c10705381f 1792 Gene3D G3DSA:3.40.50.980 1336 1491 2.5E-35 T 28-03-2018 CIG75_RS09785 9e96a118f49c91f5fa7b63c10705381f 1792 Gene3D G3DSA:3.30.559.10 697 899 4.4E-32 T 28-03-2018 CIG75_RS09785 9e96a118f49c91f5fa7b63c10705381f 1792 SMART SM00823 Phosphopantetheine attachment site 1695 1764 0.0059 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS09785 9e96a118f49c91f5fa7b63c10705381f 1792 SMART SM00823 Phosphopantetheine attachment site 622 694 9.8E-7 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS09785 9e96a118f49c91f5fa7b63c10705381f 1792 SUPERFAMILY SSF47336 617 701 4.32E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS09785 9e96a118f49c91f5fa7b63c10705381f 1792 Gene3D G3DSA:1.10.1200.10 602 695 5.8E-14 T 28-03-2018 CIG75_RS09785 9e96a118f49c91f5fa7b63c10705381f 1792 SUPERFAMILY SSF56801 1151 1707 3.4E-157 T 28-03-2018 CIG75_RS09785 9e96a118f49c91f5fa7b63c10705381f 1792 Gene3D G3DSA:1.10.1200.10 1699 1773 1.3E-17 T 28-03-2018 CIG75_RS09785 9e96a118f49c91f5fa7b63c10705381f 1792 Gene3D G3DSA:3.40.50.980 11 180 5.7E-34 T 28-03-2018 CIG75_RS09785 9e96a118f49c91f5fa7b63c10705381f 1792 Gene3D G3DSA:3.40.50.980 1181 1335 1.0E-51 T 28-03-2018 CIG75_RS09785 9e96a118f49c91f5fa7b63c10705381f 1792 SUPERFAMILY SSF56801 11 574 2.49E-111 T 28-03-2018 CIG75_RS09785 9e96a118f49c91f5fa7b63c10705381f 1792 Pfam PF13193 AMP-binding enzyme C-terminal domain 1597 1667 1.5E-14 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS09785 9e96a118f49c91f5fa7b63c10705381f 1792 Pfam PF00668 Condensation domain 713 1170 7.3E-92 T 28-03-2018 IPR001242 Condensation domain CIG75_RS09785 9e96a118f49c91f5fa7b63c10705381f 1792 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1330 1341 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS09785 9e96a118f49c91f5fa7b63c10705381f 1792 Pfam PF00550 Phosphopantetheine attachment site 1697 1758 2.2E-8 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS09785 9e96a118f49c91f5fa7b63c10705381f 1792 Pfam PF00550 Phosphopantetheine attachment site 626 687 6.0E-9 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS09785 9e96a118f49c91f5fa7b63c10705381f 1792 Gene3D G3DSA:2.30.38.10 1492 1581 9.6E-23 T 28-03-2018 CIG75_RS09785 9e96a118f49c91f5fa7b63c10705381f 1792 Gene3D G3DSA:2.30.38.10 361 462 2.2E-19 T 28-03-2018 CIG75_RS09785 9e96a118f49c91f5fa7b63c10705381f 1792 Gene3D G3DSA:3.30.300.30 463 572 2.4E-16 T 28-03-2018 CIG75_RS09785 9e96a118f49c91f5fa7b63c10705381f 1792 SUPERFAMILY SSF47336 1687 1760 1.44E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS09785 9e96a118f49c91f5fa7b63c10705381f 1792 Pfam PF00501 AMP-binding enzyme 22 471 5.9E-86 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS09785 9e96a118f49c91f5fa7b63c10705381f 1792 Pfam PF00501 AMP-binding enzyme 1190 1589 4.4E-104 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS09785 9e96a118f49c91f5fa7b63c10705381f 1792 Gene3D G3DSA:3.30.300.30 1584 1698 1.2E-36 T 28-03-2018 CIG75_RS09785 9e96a118f49c91f5fa7b63c10705381f 1792 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1211 1612 3.2E-137 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS09785 9e96a118f49c91f5fa7b63c10705381f 1792 SUPERFAMILY SSF52777 717 890 1.33E-38 T 28-03-2018 CIG75_RS06620 aefd0de4dd3e3fca85b11c9f2a8d6c54 419 SUPERFAMILY SSF51679 70 408 4.48E-64 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CIG75_RS06620 aefd0de4dd3e3fca85b11c9f2a8d6c54 419 Gene3D G3DSA:3.20.20.30 69 409 6.0E-57 T 28-03-2018 CIG75_RS06620 aefd0de4dd3e3fca85b11c9f2a8d6c54 419 Pfam PF00296 Luciferase-like monooxygenase 78 384 6.8E-42 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CIG75_RS06620 aefd0de4dd3e3fca85b11c9f2a8d6c54 419 TIGRFAM TIGR04020 seco_metab_LLM: natural product biosynthesis luciferase-like monooxygenase domain 72 409 3.2E-138 T 28-03-2018 IPR024011 Natural product biosynthesis luciferase-like monooxygenase domain CIG75_RS05395 7ef425d29b624af14215f821f4a816e4 388 TIGRFAM TIGR02877 spore_yhbH: sporulation protein YhbH 7 379 3.3E-176 T 28-03-2018 IPR014230 Sporulation protein YhbH CIG75_RS05395 7ef425d29b624af14215f821f4a816e4 388 SUPERFAMILY SSF53300 215 338 5.93E-5 T 28-03-2018 IPR002035 von Willebrand factor, type A CIG75_RS05395 7ef425d29b624af14215f821f4a816e4 388 Pfam PF04285 Protein of unknown function (DUF444) 12 189 8.7E-37 T 28-03-2018 IPR006698 Uncharacterised protein family UPF0229 CIG75_RS05395 7ef425d29b624af14215f821f4a816e4 388 Pfam PF04285 Protein of unknown function (DUF444) 192 380 4.9E-70 T 28-03-2018 IPR006698 Uncharacterised protein family UPF0229 CIG75_RS11170 3f33c57ffe9427be9ef4ffb434134719 569 Gene3D G3DSA:1.20.1600.10 17 453 3.9E-30 T 28-03-2018 CIG75_RS11170 3f33c57ffe9427be9ef4ffb434134719 569 SUPERFAMILY SSF56954 6 262 2.09E-14 T 28-03-2018 CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 SUPERFAMILY SSF52777 2168 2345 3.56E-50 T 28-03-2018 CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 SUPERFAMILY SSF52777 3421 3661 5.56E-63 T 28-03-2018 CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 SUPERFAMILY SSF56801 2587 3155 7.59E-157 T 28-03-2018 CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 SUPERFAMILY SSF52777 50 227 5.78E-50 T 28-03-2018 CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 SUPERFAMILY SSF52777 233 499 2.56E-60 T 28-03-2018 CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 SUPERFAMILY SSF56801 3660 4223 2.88E-167 T 28-03-2018 CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1712 1723 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 SUPERFAMILY SSF52777 1293 1557 9.45E-66 T 28-03-2018 CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 Pfam PF00501 AMP-binding enzyme 2630 3031 6.2E-90 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 Pfam PF00501 AMP-binding enzyme 3697 4102 1.7E-108 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 Pfam PF00501 AMP-binding enzyme 511 914 1.3E-89 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 Pfam PF00501 AMP-binding enzyme 1571 1967 2.1E-103 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 SUPERFAMILY SSF47336 1012 1118 2.62E-19 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 Pfam PF00975 Thioesterase domain 4299 4549 2.9E-33 T 28-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 SUPERFAMILY SSF52777 3236 3413 7.34E-50 T 28-03-2018 CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 ProSitePatterns PS00455 Putative AMP-binding domain signature. 650 661 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 SUPERFAMILY SSF53474 4278 4553 2.17E-56 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 Pfam PF00668 Condensation domain 1103 1549 3.3E-120 T 28-03-2018 IPR001242 Condensation domain CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 Pfam PF00668 Condensation domain 3231 3677 1.1E-119 T 28-03-2018 IPR001242 Condensation domain CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 Pfam PF00668 Condensation domain 2165 2610 2.1E-125 T 28-03-2018 IPR001242 Condensation domain CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 Pfam PF00668 Condensation domain 48 491 2.2E-116 T 28-03-2018 IPR001242 Condensation domain CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 SUPERFAMILY SSF47336 4203 4277 1.23E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4235 4250 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 Gene3D G3DSA:1.10.1200.10 2083 2149 8.5E-21 T 28-03-2018 CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 Gene3D G3DSA:1.10.1200.10 1023 1085 8.1E-21 T 28-03-2018 CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 Gene3D G3DSA:2.30.38.10 1876 1957 9.7E-23 T 28-03-2018 CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 SUPERFAMILY SSF56801 1531 2089 3.4E-166 T 28-03-2018 CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 SUPERFAMILY SSF56801 470 1028 1.44E-143 T 28-03-2018 CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 SMART SM00823 Phosphopantetheine attachment site 4214 4280 8.7E-4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 SMART SM00823 Phosphopantetheine attachment site 1017 1086 3.9E-7 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 SMART SM00823 Phosphopantetheine attachment site 2077 2146 0.042 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 SMART SM00823 Phosphopantetheine attachment site 3142 3211 6.9E-4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1041 1056 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 SUPERFAMILY SSF47336 2070 2178 7.98E-19 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3166 3181 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 Gene3D G3DSA:3.40.50.980 1561 1717 7.7E-48 T 28-03-2018 CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 Gene3D G3DSA:3.40.50.980 3688 3843 3.3E-48 T 28-03-2018 CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 Gene3D G3DSA:3.40.50.980 2621 2773 1.5E-47 T 28-03-2018 CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 ProSitePatterns PS00455 Putative AMP-binding domain signature. 3838 3849 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 Gene3D G3DSA:1.10.1200.10 3146 3214 1.4E-22 T 28-03-2018 CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 Gene3D G3DSA:1.10.1200.10 4197 4285 3.9E-18 T 28-03-2018 CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 Gene3D G3DSA:3.40.50.1820 4286 4554 2.9E-25 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 Pfam PF13193 AMP-binding enzyme C-terminal domain 3039 3114 2.8E-11 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 Pfam PF13193 AMP-binding enzyme C-terminal domain 1975 2050 9.3E-8 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 Pfam PF13193 AMP-binding enzyme C-terminal domain 4110 4185 1.0E-13 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 Pfam PF13193 AMP-binding enzyme C-terminal domain 922 991 7.3E-10 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 Gene3D G3DSA:3.30.300.30 1962 2082 3.5E-37 T 28-03-2018 CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 Gene3D G3DSA:3.30.300.30 909 1022 8.0E-32 T 28-03-2018 CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 Gene3D G3DSA:3.30.300.30 3026 3145 1.1E-40 T 28-03-2018 CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 SUPERFAMILY SSF52777 1108 1285 2.0E-50 T 28-03-2018 CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 SUPERFAMILY SSF52777 2352 2617 6.67E-72 T 28-03-2018 CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 Pfam PF00550 Phosphopantetheine attachment site 2079 2141 4.0E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 Pfam PF00550 Phosphopantetheine attachment site 4218 4275 8.2E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 Pfam PF00550 Phosphopantetheine attachment site 1020 1081 1.5E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 Pfam PF00550 Phosphopantetheine attachment site 3144 3207 9.4E-18 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 Gene3D G3DSA:2.30.38.10 823 907 4.4E-19 T 28-03-2018 CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 Gene3D G3DSA:2.30.38.10 4011 4095 9.3E-24 T 28-03-2018 CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 Gene3D G3DSA:2.30.38.10 2940 3024 1.3E-21 T 28-03-2018 CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 Gene3D G3DSA:3.40.50.980 3844 4009 9.0E-42 T 28-03-2018 CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 Gene3D G3DSA:3.40.50.980 2774 2934 2.3E-30 T 28-03-2018 CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 Gene3D G3DSA:3.40.50.980 1718 1875 2.8E-43 T 28-03-2018 CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 Gene3D G3DSA:3.40.50.980 656 819 8.6E-34 T 28-03-2018 CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 Gene3D G3DSA:3.30.300.30 4096 4196 2.7E-35 T 28-03-2018 CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1593 1991 2.6E-135 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 532 938 3.9E-126 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 3718 4126 8.7E-140 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2651 3055 1.4E-128 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 Gene3D G3DSA:3.30.559.10 2150 2355 1.8E-43 T 28-03-2018 CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 Gene3D G3DSA:3.30.559.10 1086 1295 4.4E-45 T 28-03-2018 CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 SUPERFAMILY SSF47336 3134 3208 1.44E-20 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 Gene3D G3DSA:3.30.559.10 3215 3435 1.4E-45 T 28-03-2018 CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 Gene3D G3DSA:3.30.559.10 21 249 2.1E-44 T 28-03-2018 CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2768 2779 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS10355 968b6cf35611dab22a9d09f087255bc1 4563 Gene3D G3DSA:3.40.50.980 506 655 1.4E-40 T 28-03-2018 CIG75_RS01165 ca3afc2bc7875a2ad18698b71afff796 312 Gene3D G3DSA:3.40.50.20 2 98 7.0E-16 T 28-03-2018 CIG75_RS01165 ca3afc2bc7875a2ad18698b71afff796 312 SUPERFAMILY SSF56059 85 285 2.79E-21 T 28-03-2018 CIG75_RS01165 ca3afc2bc7875a2ad18698b71afff796 312 Gene3D G3DSA:3.30.470.20 99 308 1.1E-19 T 28-03-2018 CIG75_RS02785 3777400464b96c4cdfd544540ef493bc 2952 Gene3D G3DSA:3.30.300.30 450 556 5.4E-10 T 28-03-2018 CIG75_RS02785 3777400464b96c4cdfd544540ef493bc 2952 SUPERFAMILY SSF47336 2688 2756 7.46E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS02785 3777400464b96c4cdfd544540ef493bc 2952 Pfam PF13193 AMP-binding enzyme C-terminal domain 2589 2664 7.4E-8 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS02785 3777400464b96c4cdfd544540ef493bc 2952 Gene3D G3DSA:3.40.47.10 685 945 2.7E-84 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS02785 3777400464b96c4cdfd544540ef493bc 2952 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2329 2340 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS02785 3777400464b96c4cdfd544540ef493bc 2952 SUPERFAMILY SSF55048 1333 1395 1.7E-8 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CIG75_RS02785 3777400464b96c4cdfd544540ef493bc 2952 Gene3D G3DSA:3.30.300.30 2576 2694 1.5E-30 T 28-03-2018 CIG75_RS02785 3777400464b96c4cdfd544540ef493bc 2952 Pfam PF00550 Phosphopantetheine attachment site 606 668 8.0E-10 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS02785 3777400464b96c4cdfd544540ef493bc 2952 Pfam PF00550 Phosphopantetheine attachment site 1594 1661 6.1E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS02785 3777400464b96c4cdfd544540ef493bc 2952 Pfam PF00550 Phosphopantetheine attachment site 2693 2755 4.8E-10 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS02785 3777400464b96c4cdfd544540ef493bc 2952 SMART SM00823 Phosphopantetheine attachment site 603 672 7.0E-10 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS02785 3777400464b96c4cdfd544540ef493bc 2952 SMART SM00823 Phosphopantetheine attachment site 1593 1665 3.6E-4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS02785 3777400464b96c4cdfd544540ef493bc 2952 SUPERFAMILY SSF47336 1592 1680 1.18E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS02785 3777400464b96c4cdfd544540ef493bc 2952 SUPERFAMILY SSF52777 1914 2155 6.67E-52 T 28-03-2018 CIG75_RS02785 3777400464b96c4cdfd544540ef493bc 2952 Gene3D G3DSA:3.40.50.980 176 350 4.9E-36 T 28-03-2018 CIG75_RS02785 3777400464b96c4cdfd544540ef493bc 2952 Gene3D G3DSA:3.40.50.980 2335 2487 6.7E-38 T 28-03-2018 CIG75_RS02785 3777400464b96c4cdfd544540ef493bc 2952 Gene3D G3DSA:1.10.1200.10 588 684 5.5E-14 T 28-03-2018 CIG75_RS02785 3777400464b96c4cdfd544540ef493bc 2952 SUPERFAMILY SSF56801 373 559 1.83E-91 T 28-03-2018 CIG75_RS02785 3777400464b96c4cdfd544540ef493bc 2952 SUPERFAMILY SSF56801 23 345 1.83E-91 T 28-03-2018 CIG75_RS02785 3777400464b96c4cdfd544540ef493bc 2952 SMART SM00825 Beta-ketoacyl synthase 693 1109 1.8E-179 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CIG75_RS02785 3777400464b96c4cdfd544540ef493bc 2952 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1619 1634 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS02785 3777400464b96c4cdfd544540ef493bc 2952 SUPERFAMILY SSF56801 2151 2702 6.41E-143 T 28-03-2018 CIG75_RS02785 3777400464b96c4cdfd544540ef493bc 2952 SUPERFAMILY SSF52777 1746 1907 1.56E-33 T 28-03-2018 CIG75_RS02785 3777400464b96c4cdfd544540ef493bc 2952 Gene3D G3DSA:3.40.47.10 949 1107 4.6E-55 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS02785 3777400464b96c4cdfd544540ef493bc 2952 Gene3D G3DSA:1.10.1200.10 1589 1699 4.1E-15 T 28-03-2018 CIG75_RS02785 3777400464b96c4cdfd544540ef493bc 2952 Gene3D G3DSA:3.30.70.250 1344 1388 1.6E-14 T 28-03-2018 CIG75_RS02785 3777400464b96c4cdfd544540ef493bc 2952 Pfam PF00501 AMP-binding enzyme 20 457 2.4E-61 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS02785 3777400464b96c4cdfd544540ef493bc 2952 Pfam PF00501 AMP-binding enzyme 2193 2581 2.1E-88 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS02785 3777400464b96c4cdfd544540ef493bc 2952 SUPERFAMILY SSF52151 1206 1333 1.12E-60 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CIG75_RS02785 3777400464b96c4cdfd544540ef493bc 2952 SUPERFAMILY SSF52151 1396 1499 1.12E-60 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CIG75_RS02785 3777400464b96c4cdfd544540ef493bc 2952 Gene3D G3DSA:1.10.1200.10 2695 2762 3.1E-13 T 28-03-2018 CIG75_RS02785 3777400464b96c4cdfd544540ef493bc 2952 SUPERFAMILY SSF47336 598 706 1.44E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS02785 3777400464b96c4cdfd544540ef493bc 2952 SUPERFAMILY SSF53901 689 1055 2.83E-98 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS02785 3777400464b96c4cdfd544540ef493bc 2952 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2212 2605 4.2E-114 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS02785 3777400464b96c4cdfd544540ef493bc 2952 Gene3D G3DSA:2.30.38.10 2488 2573 2.1E-21 T 28-03-2018 CIG75_RS02785 3777400464b96c4cdfd544540ef493bc 2952 Gene3D G3DSA:2.30.38.10 363 449 1.6E-17 T 28-03-2018 CIG75_RS02785 3777400464b96c4cdfd544540ef493bc 2952 Gene3D G3DSA:3.40.366.10 1205 1343 8.2E-42 T 28-03-2018 CIG75_RS02785 3777400464b96c4cdfd544540ef493bc 2952 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1060 1165 6.0E-13 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS02785 3777400464b96c4cdfd544540ef493bc 2952 ProSitePatterns PS00455 Putative AMP-binding domain signature. 170 181 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS02785 3777400464b96c4cdfd544540ef493bc 2952 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1209 1503 7.1E-79 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CIG75_RS02785 3777400464b96c4cdfd544540ef493bc 2952 Gene3D G3DSA:3.40.50.980 2183 2334 4.6E-41 T 28-03-2018 CIG75_RS02785 3777400464b96c4cdfd544540ef493bc 2952 Gene3D G3DSA:3.40.50.980 4 175 2.1E-20 T 28-03-2018 CIG75_RS02785 3777400464b96c4cdfd544540ef493bc 2952 Gene3D G3DSA:3.30.559.10 1716 1929 4.6E-29 T 28-03-2018 CIG75_RS02785 3777400464b96c4cdfd544540ef493bc 2952 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 943 1056 2.9E-40 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CIG75_RS02785 3777400464b96c4cdfd544540ef493bc 2952 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 847 863 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CIG75_RS02785 3777400464b96c4cdfd544540ef493bc 2952 Pfam PF00698 Acyl transferase domain 1207 1504 2.2E-56 T 28-03-2018 IPR014043 Acyl transferase CIG75_RS02785 3777400464b96c4cdfd544540ef493bc 2952 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 692 934 1.5E-80 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CIG75_RS02785 3777400464b96c4cdfd544540ef493bc 2952 Pfam PF00668 Condensation domain 1747 2172 3.1E-88 T 28-03-2018 IPR001242 Condensation domain CIG75_RS02785 3777400464b96c4cdfd544540ef493bc 2952 Gene3D G3DSA:3.40.366.10 1389 1508 8.1E-19 T 28-03-2018 CIG75_RS08255 e93ff67be9dfc74adccc26571b9a4ad3 365 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 4 363 2.1E-134 T 28-03-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 CIG75_RS08255 e93ff67be9dfc74adccc26571b9a4ad3 365 Gene3D G3DSA:2.40.30.110 282 365 4.4E-22 T 28-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CIG75_RS08255 e93ff67be9dfc74adccc26571b9a4ad3 365 PIRSF PIRSF006487 1 365 6.7E-103 T 28-03-2018 CIG75_RS08255 e93ff67be9dfc74adccc26571b9a4ad3 365 SUPERFAMILY SSF101790 274 364 2.94E-24 T 28-03-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain CIG75_RS08255 e93ff67be9dfc74adccc26571b9a4ad3 365 Gene3D G3DSA:4.10.1250.10 239 280 4.1E-19 T 28-03-2018 CIG75_RS08255 e93ff67be9dfc74adccc26571b9a4ad3 365 SUPERFAMILY SSF103025 3 282 7.06E-102 T 28-03-2018 CIG75_RS08255 e93ff67be9dfc74adccc26571b9a4ad3 365 Gene3D G3DSA:3.30.1360.120 122 237 3.3E-34 T 28-03-2018 CIG75_RS08255 e93ff67be9dfc74adccc26571b9a4ad3 365 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 266 357 2.9E-27 T 28-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CIG75_RS08255 e93ff67be9dfc74adccc26571b9a4ad3 365 Hamap MF_00259 Aminomethyltransferase [gcvT]. 3 363 47.29 T 28-03-2018 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CIG75_RS08255 e93ff67be9dfc74adccc26571b9a4ad3 365 Gene3D G3DSA:3.30.1360.120 4 121 3.5E-28 T 28-03-2018 CIG75_RS08255 e93ff67be9dfc74adccc26571b9a4ad3 365 Pfam PF01571 Aminomethyltransferase folate-binding domain 15 260 2.4E-91 T 28-03-2018 IPR006222 Glycine cleavage T-protein-like, N-terminal CIG75_RS09940 ec6b05a5244549571221f5efae0467fd 318 SUPERFAMILY SSF50249 204 306 2.57E-15 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CIG75_RS09940 ec6b05a5244549571221f5efae0467fd 318 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 27 35 - T 28-03-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 CIG75_RS09940 ec6b05a5244549571221f5efae0467fd 318 Pfam PF01068 ATP dependent DNA ligase domain 22 197 1.7E-33 T 28-03-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 CIG75_RS09940 ec6b05a5244549571221f5efae0467fd 318 SUPERFAMILY SSF56091 3 197 4.03E-36 T 28-03-2018 CIG75_RS09940 ec6b05a5244549571221f5efae0467fd 318 Gene3D G3DSA:2.40.50.140 187 312 3.4E-19 T 28-03-2018 CIG75_RS09940 ec6b05a5244549571221f5efae0467fd 318 Gene3D G3DSA:3.30.470.30 25 144 7.1E-25 T 28-03-2018 CIG75_RS09940 ec6b05a5244549571221f5efae0467fd 318 Pfam PF04679 ATP dependent DNA ligase C terminal region 212 306 4.3E-18 T 28-03-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 CIG75_RS09940 ec6b05a5244549571221f5efae0467fd 318 Gene3D G3DSA:3.30.1490.70 145 186 4.9E-8 T 28-03-2018 CIG75_RS14905 71a78c231b3ff24677d6b54f7ae90341 396 SUPERFAMILY SSF51905 4 330 4.15E-34 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS14905 71a78c231b3ff24677d6b54f7ae90341 396 Gene3D G3DSA:3.50.50.60 2 123 5.3E-12 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS14905 71a78c231b3ff24677d6b54f7ae90341 396 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 152 177 9.2E-8 T 28-03-2018 CIG75_RS14905 71a78c231b3ff24677d6b54f7ae90341 396 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 287 294 9.2E-8 T 28-03-2018 CIG75_RS14905 71a78c231b3ff24677d6b54f7ae90341 396 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 9.2E-8 T 28-03-2018 CIG75_RS14905 71a78c231b3ff24677d6b54f7ae90341 396 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 315 1.4E-44 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS14905 71a78c231b3ff24677d6b54f7ae90341 396 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 96 114 1.9E-9 T 28-03-2018 CIG75_RS14905 71a78c231b3ff24677d6b54f7ae90341 396 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 152 170 1.9E-9 T 28-03-2018 CIG75_RS14905 71a78c231b3ff24677d6b54f7ae90341 396 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 1.9E-9 T 28-03-2018 CIG75_RS14905 71a78c231b3ff24677d6b54f7ae90341 396 Gene3D G3DSA:3.50.50.60 124 158 0.45 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS14905 71a78c231b3ff24677d6b54f7ae90341 396 Gene3D G3DSA:3.40.50.720 159 362 1.9E-28 T 28-03-2018 CIG75_RS17405 e10336dc2c3f0ca8a4029e0e0ac2c4cc 469 Pfam PF01471 Putative peptidoglycan binding domain 388 442 6.8E-13 T 28-03-2018 IPR002477 Peptidoglycan binding-like CIG75_RS17405 e10336dc2c3f0ca8a4029e0e0ac2c4cc 469 Pfam PF03572 Peptidase family S41 204 364 2.4E-50 T 28-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 CIG75_RS17405 e10336dc2c3f0ca8a4029e0e0ac2c4cc 469 Gene3D G3DSA:3.90.226.10 186 377 4.3E-59 T 28-03-2018 CIG75_RS17405 e10336dc2c3f0ca8a4029e0e0ac2c4cc 469 SUPERFAMILY SSF50156 99 187 1.31E-16 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CIG75_RS17405 e10336dc2c3f0ca8a4029e0e0ac2c4cc 469 Gene3D G3DSA:2.30.42.10 110 185 3.8E-17 T 28-03-2018 CIG75_RS17405 e10336dc2c3f0ca8a4029e0e0ac2c4cc 469 Pfam PF13180 PDZ domain 106 185 5.7E-12 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CIG75_RS17405 e10336dc2c3f0ca8a4029e0e0ac2c4cc 469 SUPERFAMILY SSF47090 378 448 3.45E-15 T 28-03-2018 IPR002477 Peptidoglycan binding-like CIG75_RS17405 e10336dc2c3f0ca8a4029e0e0ac2c4cc 469 Gene3D G3DSA:3.30.750.44 35 109 5.7E-18 T 28-03-2018 CIG75_RS17405 e10336dc2c3f0ca8a4029e0e0ac2c4cc 469 SMART SM00228 105 176 1.1E-16 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CIG75_RS17405 e10336dc2c3f0ca8a4029e0e0ac2c4cc 469 SMART SM00245 178 365 5.4E-68 T 28-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 CIG75_RS17405 e10336dc2c3f0ca8a4029e0e0ac2c4cc 469 Gene3D G3DSA:1.10.101.10 378 453 2.3E-17 T 28-03-2018 IPR002477 Peptidoglycan binding-like CIG75_RS17405 e10336dc2c3f0ca8a4029e0e0ac2c4cc 469 SUPERFAMILY SSF52096 197 369 2.15E-70 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CIG75_RS17405 e10336dc2c3f0ca8a4029e0e0ac2c4cc 469 SUPERFAMILY SSF52096 41 123 2.15E-70 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CIG75_RS17405 e10336dc2c3f0ca8a4029e0e0ac2c4cc 469 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 60 373 7.9E-107 T 28-03-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 CIG75_RS09415 bc388abccfe73d0eb26894b616d654aa 126 Gene3D G3DSA:2.40.50.100 6 126 2.7E-45 T 28-03-2018 CIG75_RS09415 bc388abccfe73d0eb26894b616d654aa 126 Pfam PF01597 Glycine cleavage H-protein 8 124 2.6E-44 T 28-03-2018 IPR033753 Glycine cleavage system H-protein/Simiate CIG75_RS09415 bc388abccfe73d0eb26894b616d654aa 126 SUPERFAMILY SSF51230 3 124 5.1E-43 T 28-03-2018 IPR011053 Single hybrid motif CIG75_RS09415 bc388abccfe73d0eb26894b616d654aa 126 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 5 125 37.633 T 28-03-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 CIG75_RS09415 bc388abccfe73d0eb26894b616d654aa 126 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 47 76 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CIG75_RS09415 bc388abccfe73d0eb26894b616d654aa 126 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 3 124 1.1E-51 T 28-03-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 CIG75_RS10310 c3bd1e868f070dce25c578ca2dc5c201 2130 SUPERFAMILY SSF47336 2041 2114 4.58E-21 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10310 c3bd1e868f070dce25c578ca2dc5c201 2130 SUPERFAMILY SSF52777 1077 1254 1.78E-49 T 28-03-2018 CIG75_RS10310 c3bd1e868f070dce25c578ca2dc5c201 2130 Pfam PF00550 Phosphopantetheine attachment site 2051 2113 1.4E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10310 c3bd1e868f070dce25c578ca2dc5c201 2130 Pfam PF00550 Phosphopantetheine attachment site 989 1051 7.3E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10310 c3bd1e868f070dce25c578ca2dc5c201 2130 SUPERFAMILY SSF52777 206 469 1.26E-68 T 28-03-2018 CIG75_RS10310 c3bd1e868f070dce25c578ca2dc5c201 2130 SMART SM00823 Phosphopantetheine attachment site 986 1055 0.0047 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS10310 c3bd1e868f070dce25c578ca2dc5c201 2130 SMART SM00823 Phosphopantetheine attachment site 2049 2118 0.0051 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS10310 c3bd1e868f070dce25c578ca2dc5c201 2130 ProSitePatterns PS00455 Putative AMP-binding domain signature. 623 634 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS10310 c3bd1e868f070dce25c578ca2dc5c201 2130 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1680 1691 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS10310 c3bd1e868f070dce25c578ca2dc5c201 2130 Gene3D G3DSA:3.30.559.10 4 223 1.1E-44 T 28-03-2018 CIG75_RS10310 c3bd1e868f070dce25c578ca2dc5c201 2130 Gene3D G3DSA:3.30.559.10 1061 1276 2.6E-48 T 28-03-2018 CIG75_RS10310 c3bd1e868f070dce25c578ca2dc5c201 2130 Gene3D G3DSA:2.30.38.10 787 867 2.8E-24 T 28-03-2018 CIG75_RS10310 c3bd1e868f070dce25c578ca2dc5c201 2130 Gene3D G3DSA:3.30.300.30 1936 2054 2.5E-39 T 28-03-2018 CIG75_RS10310 c3bd1e868f070dce25c578ca2dc5c201 2130 Gene3D G3DSA:3.30.300.30 872 991 6.7E-40 T 28-03-2018 CIG75_RS10310 c3bd1e868f070dce25c578ca2dc5c201 2130 SUPERFAMILY SSF47336 978 1087 7.59E-20 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10310 c3bd1e868f070dce25c578ca2dc5c201 2130 SUPERFAMILY SSF56801 442 999 2.22E-166 T 28-03-2018 CIG75_RS10310 c3bd1e868f070dce25c578ca2dc5c201 2130 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1559 1965 3.6E-132 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS10310 c3bd1e868f070dce25c578ca2dc5c201 2130 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 502 901 4.2E-141 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS10310 c3bd1e868f070dce25c578ca2dc5c201 2130 SUPERFAMILY SSF52777 1262 1525 6.23E-70 T 28-03-2018 CIG75_RS10310 c3bd1e868f070dce25c578ca2dc5c201 2130 Gene3D G3DSA:3.40.50.980 1686 1850 8.5E-38 T 28-03-2018 CIG75_RS10310 c3bd1e868f070dce25c578ca2dc5c201 2130 Gene3D G3DSA:3.40.50.980 628 786 5.0E-32 T 28-03-2018 CIG75_RS10310 c3bd1e868f070dce25c578ca2dc5c201 2130 Pfam PF00668 Condensation domain 1074 1518 3.1E-118 T 28-03-2018 IPR001242 Condensation domain CIG75_RS10310 c3bd1e868f070dce25c578ca2dc5c201 2130 Pfam PF00668 Condensation domain 19 462 3.7E-122 T 28-03-2018 IPR001242 Condensation domain CIG75_RS10310 c3bd1e868f070dce25c578ca2dc5c201 2130 Gene3D G3DSA:2.30.38.10 1852 1934 4.8E-23 T 28-03-2018 CIG75_RS10310 c3bd1e868f070dce25c578ca2dc5c201 2130 SUPERFAMILY SSF52777 22 198 4.56E-49 T 28-03-2018 CIG75_RS10310 c3bd1e868f070dce25c578ca2dc5c201 2130 Gene3D G3DSA:3.40.50.980 1530 1685 9.6E-49 T 28-03-2018 CIG75_RS10310 c3bd1e868f070dce25c578ca2dc5c201 2130 Gene3D G3DSA:1.10.1200.10 992 1060 2.6E-20 T 28-03-2018 CIG75_RS10310 c3bd1e868f070dce25c578ca2dc5c201 2130 Gene3D G3DSA:1.10.1200.10 2055 2121 3.0E-23 T 28-03-2018 CIG75_RS10310 c3bd1e868f070dce25c578ca2dc5c201 2130 SUPERFAMILY SSF56801 1497 2062 3.79E-164 T 28-03-2018 CIG75_RS10310 c3bd1e868f070dce25c578ca2dc5c201 2130 Pfam PF00501 AMP-binding enzyme 481 877 3.2E-105 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS10310 c3bd1e868f070dce25c578ca2dc5c201 2130 Pfam PF00501 AMP-binding enzyme 1538 1941 3.1E-102 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS10310 c3bd1e868f070dce25c578ca2dc5c201 2130 Pfam PF13193 AMP-binding enzyme C-terminal domain 885 960 1.1E-12 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS10310 c3bd1e868f070dce25c578ca2dc5c201 2130 Pfam PF13193 AMP-binding enzyme C-terminal domain 1949 2024 1.2E-11 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS10310 c3bd1e868f070dce25c578ca2dc5c201 2130 Gene3D G3DSA:3.40.50.980 474 627 1.0E-52 T 28-03-2018 CIG75_RS10310 c3bd1e868f070dce25c578ca2dc5c201 2130 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1010 1025 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS10310 c3bd1e868f070dce25c578ca2dc5c201 2130 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2073 2088 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS13065 32fb15c321bb1a256083cce6b0dcf6a2 561 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 176 187 - T 28-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site CIG75_RS13065 32fb15c321bb1a256083cce6b0dcf6a2 561 SUPERFAMILY SSF52743 74 471 1.31E-90 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CIG75_RS13065 32fb15c321bb1a256083cce6b0dcf6a2 561 Gene3D G3DSA:2.60.120.380 462 561 2.1E-16 T 28-03-2018 CIG75_RS13065 32fb15c321bb1a256083cce6b0dcf6a2 561 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 216 226 - T 28-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site CIG75_RS13065 32fb15c321bb1a256083cce6b0dcf6a2 561 Gene3D G3DSA:3.40.50.200 125 452 3.8E-89 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CIG75_RS13065 32fb15c321bb1a256083cce6b0dcf6a2 561 Pfam PF00082 Subtilase family 172 439 5.8E-59 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CIG75_RS13065 32fb15c321bb1a256083cce6b0dcf6a2 561 PRINTS PR00723 Subtilisin serine protease family (S8) signature 212 225 9.0E-19 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CIG75_RS13065 32fb15c321bb1a256083cce6b0dcf6a2 561 PRINTS PR00723 Subtilisin serine protease family (S8) signature 171 190 9.0E-19 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CIG75_RS13065 32fb15c321bb1a256083cce6b0dcf6a2 561 PRINTS PR00723 Subtilisin serine protease family (S8) signature 388 404 9.0E-19 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CIG75_RS13065 32fb15c321bb1a256083cce6b0dcf6a2 561 Pfam PF04151 Bacterial pre-peptidase C-terminal domain 476 547 1.6E-10 T 28-03-2018 IPR007280 Peptidase, C-terminal, archaeal/bacterial CIG75_RS13065 32fb15c321bb1a256083cce6b0dcf6a2 561 Pfam PF05922 Peptidase inhibitor I9 92 137 3.1E-7 T 28-03-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 CIG75_RS13065 32fb15c321bb1a256083cce6b0dcf6a2 561 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 389 399 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CIG75_RS13065 32fb15c321bb1a256083cce6b0dcf6a2 561 Gene3D G3DSA:3.30.70.80 69 124 3.5E-12 T 28-03-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 SUPERFAMILY SSF56801 3644 4210 1.31E-158 T 28-03-2018 CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 SUPERFAMILY SSF52777 218 458 2.78E-66 T 28-03-2018 CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 SUPERFAMILY SSF52777 3409 3670 3.45E-66 T 28-03-2018 CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 Gene3D G3DSA:3.30.300.30 892 1013 5.8E-40 T 28-03-2018 CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 Gene3D G3DSA:3.30.300.30 3018 3138 6.5E-41 T 28-03-2018 CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 Gene3D G3DSA:3.30.300.30 1962 2081 3.3E-35 T 28-03-2018 CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 Gene3D G3DSA:3.30.300.30 4086 4202 6.7E-34 T 28-03-2018 CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 SUPERFAMILY SSF47336 4191 4263 1.44E-19 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 SUPERFAMILY SSF47336 2069 2141 4.32E-20 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 Gene3D G3DSA:2.30.38.10 3999 4081 2.5E-24 T 28-03-2018 CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 SUPERFAMILY SSF56801 1524 2089 6.67E-132 T 28-03-2018 CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 Gene3D G3DSA:1.10.1200.10 4203 4267 1.5E-22 T 28-03-2018 CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 Gene3D G3DSA:1.10.1200.10 3139 3203 4.3E-24 T 28-03-2018 CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 SUPERFAMILY SSF56801 454 1021 4.06E-159 T 28-03-2018 CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 SMART SM00823 Phosphopantetheine attachment site 3133 3202 1.0E-4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 SMART SM00823 Phosphopantetheine attachment site 4197 4266 4.3E-4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 SMART SM00823 Phosphopantetheine attachment site 2076 2145 0.002 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 SMART SM00823 Phosphopantetheine attachment site 1008 1077 4.5E-7 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 514 921 2.8E-130 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1583 1991 9.7E-104 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 3708 4115 1.8E-139 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2644 3047 5.5E-137 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 SUPERFAMILY SSF47336 1001 1074 4.84E-22 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 SUPERFAMILY SSF52777 2167 2338 3.19E-45 T 28-03-2018 CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 SUPERFAMILY SSF52777 3225 3403 5.93E-48 T 28-03-2018 CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 Pfam PF00501 AMP-binding enzyme 3687 4091 1.9E-100 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 Pfam PF00501 AMP-binding enzyme 1565 1967 1.7E-81 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 Pfam PF00501 AMP-binding enzyme 493 897 1.8E-94 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 Pfam PF00501 AMP-binding enzyme 2623 3023 1.8E-101 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 Gene3D G3DSA:1.10.1200.10 1014 1087 2.6E-25 T 28-03-2018 CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 Gene3D G3DSA:1.10.1200.10 2082 2154 2.3E-23 T 28-03-2018 CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 SUPERFAMILY SSF52777 1102 1279 1.11E-48 T 28-03-2018 CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 SUPERFAMILY SSF52777 34 210 3.34E-49 T 28-03-2018 CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 SUPERFAMILY SSF56801 2582 3145 1.83E-171 T 28-03-2018 CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 Gene3D G3DSA:3.40.50.980 2614 2754 1.6E-35 T 28-03-2018 CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 ProSitePatterns PS00455 Putative AMP-binding domain signature. 632 643 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4221 4236 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2100 2115 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 ProSitePatterns PS00455 Putative AMP-binding domain signature. 3828 3839 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 Gene3D G3DSA:3.30.559.10 5 236 6.6E-42 T 28-03-2018 CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 Pfam PF13193 AMP-binding enzyme C-terminal domain 3031 3106 7.2E-14 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 Pfam PF13193 AMP-binding enzyme C-terminal domain 4099 4169 1.4E-5 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 Pfam PF13193 AMP-binding enzyme C-terminal domain 1975 2049 2.4E-10 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 Pfam PF13193 AMP-binding enzyme C-terminal domain 905 980 3.0E-10 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 SUPERFAMILY SSF47336 3125 3198 1.27E-20 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 Gene3D G3DSA:3.30.559.10 3206 3413 4.2E-37 T 28-03-2018 CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 Gene3D G3DSA:3.30.559.10 1088 1284 1.5E-41 T 28-03-2018 CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 Gene3D G3DSA:3.30.559.10 2155 2342 7.3E-37 T 28-03-2018 CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 Pfam PF00668 Condensation domain 2163 2603 1.4E-115 T 28-03-2018 IPR001242 Condensation domain CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 Pfam PF00668 Condensation domain 1098 1542 4.7E-112 T 28-03-2018 IPR001242 Condensation domain CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 Pfam PF00668 Condensation domain 3222 3666 2.6E-115 T 28-03-2018 IPR001242 Condensation domain CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 Pfam PF00668 Condensation domain 31 475 1.1E-121 T 28-03-2018 IPR001242 Condensation domain CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 SUPERFAMILY SSF52777 2346 2610 4.45E-66 T 28-03-2018 CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 Gene3D G3DSA:3.40.50.980 1554 1712 2.1E-31 T 28-03-2018 CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 Gene3D G3DSA:3.40.50.980 3679 3834 8.7E-46 T 28-03-2018 CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 Gene3D G3DSA:3.40.50.980 484 637 1.5E-41 T 28-03-2018 CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 Gene3D G3DSA:2.30.38.10 2936 3016 8.2E-26 T 28-03-2018 CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 Gene3D G3DSA:2.30.38.10 806 890 1.9E-20 T 28-03-2018 CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 Gene3D G3DSA:2.30.38.10 1876 1960 1.5E-16 T 28-03-2018 CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 SUPERFAMILY SSF52777 1287 1526 1.67E-57 T 28-03-2018 CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1707 1718 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 Gene3D G3DSA:3.40.50.980 2755 2935 8.1E-49 T 28-03-2018 CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 Pfam PF00550 Phosphopantetheine attachment site 1010 1073 1.1E-17 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 Pfam PF00550 Phosphopantetheine attachment site 2078 2141 3.6E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 Pfam PF00550 Phosphopantetheine attachment site 4200 4261 1.1E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 Pfam PF00550 Phosphopantetheine attachment site 3136 3198 1.3E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 Gene3D G3DSA:3.40.50.980 3835 3998 1.0E-36 T 28-03-2018 CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 Gene3D G3DSA:3.40.50.980 1713 1874 1.8E-35 T 28-03-2018 CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 Gene3D G3DSA:3.40.50.980 638 803 2.9E-39 T 28-03-2018 CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2768 2779 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS10350 eddcb28e6a3d04ec739c39edd6549fd0 4279 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1032 1047 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS03915 2dbd18debb69fd87fb90d5cf97303126 494 SMART SM00382 30 190 1.0E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS03915 2dbd18debb69fd87fb90d5cf97303126 494 SMART SM00382 334 494 0.013 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS03915 2dbd18debb69fd87fb90d5cf97303126 494 SUPERFAMILY SSF52540 3 194 1.27E-33 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS03915 2dbd18debb69fd87fb90d5cf97303126 494 Gene3D G3DSA:3.40.50.300 310 494 1.1E-42 T 28-03-2018 CIG75_RS03915 2dbd18debb69fd87fb90d5cf97303126 494 SUPERFAMILY SSF52540 299 494 2.31E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS03915 2dbd18debb69fd87fb90d5cf97303126 494 Pfam PF00005 ABC transporter 326 451 7.5E-22 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS03915 2dbd18debb69fd87fb90d5cf97303126 494 Pfam PF00005 ABC transporter 22 146 7.7E-18 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS03915 2dbd18debb69fd87fb90d5cf97303126 494 Gene3D G3DSA:3.40.50.300 1 309 1.0E-38 T 28-03-2018 CIG75_RS03915 2dbd18debb69fd87fb90d5cf97303126 494 ProSitePatterns PS00211 ABC transporters family signature. 423 437 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS08800 79e1e9eab7874ad3bac11ea6b378cf0d 198 SUPERFAMILY SSF46785 3 80 1.43E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS08800 79e1e9eab7874ad3bac11ea6b378cf0d 198 Pfam PF04079 Segregation and condensation complex subunit ScpB 9 167 7.3E-57 T 28-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CIG75_RS08800 79e1e9eab7874ad3bac11ea6b378cf0d 198 Gene3D G3DSA:1.10.10.10 85 176 9.7E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS08800 79e1e9eab7874ad3bac11ea6b378cf0d 198 PIRSF PIRSF019345 1 195 5.7E-56 T 28-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CIG75_RS08800 79e1e9eab7874ad3bac11ea6b378cf0d 198 Gene3D G3DSA:1.10.10.10 1 84 9.4E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS08800 79e1e9eab7874ad3bac11ea6b378cf0d 198 SUPERFAMILY SSF46785 85 159 3.86E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS08800 79e1e9eab7874ad3bac11ea6b378cf0d 198 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 6 170 1.2E-47 T 28-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CIG75_RS08800 79e1e9eab7874ad3bac11ea6b378cf0d 198 Hamap MF_01804 Segregation and condensation protein B [scpB]. 1 186 32.687 T 28-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CIG75_RS02350 9c84d24fc36284b32ee86e337d01f96a 515 SUPERFAMILY SSF64518 152 508 6.93E-20 T 28-03-2018 CIG75_RS02350 9c84d24fc36284b32ee86e337d01f96a 515 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 453 508 3.1E-11 T 28-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain CIG75_RS02350 9c84d24fc36284b32ee86e337d01f96a 515 TIGRFAM TIGR02492 flgK_ends: flagellar hook-associated protein FlgK 8 508 4.0E-87 T 28-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 CIG75_RS02350 9c84d24fc36284b32ee86e337d01f96a 515 Pfam PF00460 Flagella basal body rod protein 8 37 2.9E-6 T 28-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 CIG75_RS02350 9c84d24fc36284b32ee86e337d01f96a 515 PRINTS PR01005 Flagellar hook-associated protein signature 429 450 7.8E-9 T 28-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 CIG75_RS02350 9c84d24fc36284b32ee86e337d01f96a 515 PRINTS PR01005 Flagellar hook-associated protein signature 476 500 7.8E-9 T 28-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 CIG75_RS02350 9c84d24fc36284b32ee86e337d01f96a 515 PRINTS PR01005 Flagellar hook-associated protein signature 14 37 7.8E-9 T 28-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 CIG75_RS15755 bfbe93c8bd62fff953237a340aff5910 524 Pfam PF06039 Malate:quinone oxidoreductase (Mqo) 31 516 1.3E-240 T 28-03-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 CIG75_RS15755 bfbe93c8bd62fff953237a340aff5910 524 Hamap MF_00212 Probable malate:quinone oxidoreductase [mqo]. 28 516 54.09 T 28-03-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 CIG75_RS15755 bfbe93c8bd62fff953237a340aff5910 524 SUPERFAMILY SSF51905 30 330 7.51E-23 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS15755 bfbe93c8bd62fff953237a340aff5910 524 TIGRFAM TIGR01320 mal_quin_oxido: malate dehydrogenase (acceptor) 32 514 1.5E-218 T 28-03-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 CIG75_RS15755 bfbe93c8bd62fff953237a340aff5910 524 Gene3D G3DSA:3.50.50.60 25 469 9.4E-17 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS07380 5c648e3dea6bf1e22eaa158b526256fa 227 Pfam PF00174 Oxidoreductase molybdopterin binding domain 26 172 2.3E-36 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CIG75_RS07380 5c648e3dea6bf1e22eaa158b526256fa 227 Gene3D G3DSA:3.90.420.10 11 200 1.0E-54 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CIG75_RS07380 5c648e3dea6bf1e22eaa158b526256fa 227 SUPERFAMILY SSF56524 8 195 8.5E-60 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CIG75_RS16930 b597bd3a688cd0a8de1cb266d95ef46a 367 Gene3D G3DSA:3.30.2110.10 10 185 1.7E-63 T 28-03-2018 CIG75_RS16930 b597bd3a688cd0a8de1cb266d95ef46a 367 SUPERFAMILY SSF111342 3 288 9.55E-87 T 28-03-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 CIG75_RS16930 b597bd3a688cd0a8de1cb266d95ef46a 367 Pfam PF01888 CbiD 8 271 2.6E-97 T 28-03-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 CIG75_RS16930 b597bd3a688cd0a8de1cb266d95ef46a 367 PIRSF PIRSF026782 4 367 6.0E-123 T 28-03-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 CIG75_RS16930 b597bd3a688cd0a8de1cb266d95ef46a 367 Hamap MF_00787 Cobalt-precorrin-5B C(1)-methyltransferase [cbiD]. 8 362 29.351 T 28-03-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 CIG75_RS16930 b597bd3a688cd0a8de1cb266d95ef46a 367 TIGRFAM TIGR00312 cbiD: cobalamin biosynthesis protein CbiD 15 360 3.8E-65 T 28-03-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 CIG75_RS15150 42e039f4ec32ec2ae8eec63a635a1f13 221 Pfam PF02581 Thiamine monophosphate synthase 10 189 6.8E-53 T 28-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CIG75_RS15150 42e039f4ec32ec2ae8eec63a635a1f13 221 Gene3D G3DSA:3.20.20.70 1 207 8.9E-51 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CIG75_RS15150 42e039f4ec32ec2ae8eec63a635a1f13 221 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 6 207 23.342 T 28-03-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CIG75_RS15150 42e039f4ec32ec2ae8eec63a635a1f13 221 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 10 202 1.9E-47 T 28-03-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CIG75_RS15150 42e039f4ec32ec2ae8eec63a635a1f13 221 SUPERFAMILY SSF51391 6 207 2.62E-63 T 28-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CIG75_RS08130 41eb512fb6bf7d504613f519cce4f7dd 194 SUPERFAMILY SSF55890 18 124 5.62E-17 T 28-03-2018 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 CIG75_RS08130 41eb512fb6bf7d504613f519cce4f7dd 194 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 18 69 1.4E-11 T 28-03-2018 CIG75_RS08130 41eb512fb6bf7d504613f519cce4f7dd 194 Gene3D G3DSA:1.10.287.130 5 69 1.7E-8 T 28-03-2018 CIG75_RS11070 d2e39c0a3f133174991a34cf1b6b8b8b 1791 Gene3D G3DSA:3.30.300.30 456 564 2.1E-16 T 28-03-2018 CIG75_RS11070 d2e39c0a3f133174991a34cf1b6b8b8b 1791 SUPERFAMILY SSF52777 703 876 2.89E-42 T 28-03-2018 CIG75_RS11070 d2e39c0a3f133174991a34cf1b6b8b8b 1791 Gene3D G3DSA:1.10.1200.10 606 696 3.5E-14 T 28-03-2018 CIG75_RS11070 d2e39c0a3f133174991a34cf1b6b8b8b 1791 SUPERFAMILY SSF52777 885 1160 1.06E-64 T 28-03-2018 CIG75_RS11070 d2e39c0a3f133174991a34cf1b6b8b8b 1791 SMART SM00823 Phosphopantetheine attachment site 612 683 1.2E-15 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS11070 d2e39c0a3f133174991a34cf1b6b8b8b 1791 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1316 1327 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS11070 d2e39c0a3f133174991a34cf1b6b8b8b 1791 ProSitePatterns PS00455 Putative AMP-binding domain signature. 169 180 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS11070 d2e39c0a3f133174991a34cf1b6b8b8b 1791 Gene3D G3DSA:3.30.300.30 1573 1690 9.3E-42 T 28-03-2018 CIG75_RS11070 d2e39c0a3f133174991a34cf1b6b8b8b 1791 Gene3D G3DSA:3.40.50.980 175 346 4.2E-33 T 28-03-2018 CIG75_RS11070 d2e39c0a3f133174991a34cf1b6b8b8b 1791 Gene3D G3DSA:3.40.50.980 1322 1487 2.8E-37 T 28-03-2018 CIG75_RS11070 d2e39c0a3f133174991a34cf1b6b8b8b 1791 Gene3D G3DSA:3.40.50.980 1165 1321 1.3E-50 T 28-03-2018 CIG75_RS11070 d2e39c0a3f133174991a34cf1b6b8b8b 1791 Gene3D G3DSA:3.40.50.980 8 174 5.2E-32 T 28-03-2018 CIG75_RS11070 d2e39c0a3f133174991a34cf1b6b8b8b 1791 Gene3D G3DSA:3.30.559.10 697 876 9.3E-33 T 28-03-2018 CIG75_RS11070 d2e39c0a3f133174991a34cf1b6b8b8b 1791 Gene3D G3DSA:1.10.1200.10 1691 1762 6.3E-17 T 28-03-2018 CIG75_RS11070 d2e39c0a3f133174991a34cf1b6b8b8b 1791 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1195 1602 3.8E-143 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS11070 d2e39c0a3f133174991a34cf1b6b8b8b 1791 Pfam PF00668 Condensation domain 703 1153 9.4E-112 T 28-03-2018 IPR001242 Condensation domain CIG75_RS11070 d2e39c0a3f133174991a34cf1b6b8b8b 1791 Pfam PF00550 Phosphopantetheine attachment site 1689 1752 2.6E-9 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS11070 d2e39c0a3f133174991a34cf1b6b8b8b 1791 Pfam PF00550 Phosphopantetheine attachment site 615 677 1.7E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS11070 d2e39c0a3f133174991a34cf1b6b8b8b 1791 SUPERFAMILY SSF47336 610 696 1.44E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS11070 d2e39c0a3f133174991a34cf1b6b8b8b 1791 Pfam PF13193 AMP-binding enzyme C-terminal domain 1586 1659 2.4E-15 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS11070 d2e39c0a3f133174991a34cf1b6b8b8b 1791 SUPERFAMILY SSF47336 1679 1753 3.4E-16 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS11070 d2e39c0a3f133174991a34cf1b6b8b8b 1791 SUPERFAMILY SSF56801 7 566 4.84E-109 T 28-03-2018 CIG75_RS11070 d2e39c0a3f133174991a34cf1b6b8b8b 1791 Pfam PF00501 AMP-binding enzyme 16 463 7.2E-82 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS11070 d2e39c0a3f133174991a34cf1b6b8b8b 1791 Pfam PF00501 AMP-binding enzyme 1174 1578 2.8E-110 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS11070 d2e39c0a3f133174991a34cf1b6b8b8b 1791 Gene3D G3DSA:2.30.38.10 374 455 2.2E-20 T 28-03-2018 CIG75_RS11070 d2e39c0a3f133174991a34cf1b6b8b8b 1791 Gene3D G3DSA:2.30.38.10 1490 1571 1.6E-25 T 28-03-2018 CIG75_RS11070 d2e39c0a3f133174991a34cf1b6b8b8b 1791 SUPERFAMILY SSF56801 1133 1700 1.1E-173 T 28-03-2018 CIG75_RS06615 9fdb33326f42765f33e4d5b28eb13e5f 1540 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 173 189 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CIG75_RS06615 9fdb33326f42765f33e4d5b28eb13e5f 1540 SUPERFAMILY SSF53901 11 127 1.67E-82 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS06615 9fdb33326f42765f33e4d5b28eb13e5f 1540 SUPERFAMILY SSF53901 156 382 1.67E-82 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS06615 9fdb33326f42765f33e4d5b28eb13e5f 1540 SUPERFAMILY SSF53901 414 435 1.67E-82 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS06615 9fdb33326f42765f33e4d5b28eb13e5f 1540 Pfam PF00698 Acyl transferase domain 535 851 5.5E-55 T 28-03-2018 IPR014043 Acyl transferase CIG75_RS06615 9fdb33326f42765f33e4d5b28eb13e5f 1540 Gene3D G3DSA:3.40.366.10 717 840 6.0E-29 T 28-03-2018 CIG75_RS06615 9fdb33326f42765f33e4d5b28eb13e5f 1540 SUPERFAMILY SSF51735 904 1115 1.71E-22 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS06615 9fdb33326f42765f33e4d5b28eb13e5f 1540 SUPERFAMILY SSF51735 1131 1174 1.33E-18 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS06615 9fdb33326f42765f33e4d5b28eb13e5f 1540 SUPERFAMILY SSF51735 1202 1428 1.33E-18 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS06615 9fdb33326f42765f33e4d5b28eb13e5f 1540 SMART SM00825 Beta-ketoacyl synthase 13 439 6.3E-186 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CIG75_RS06615 9fdb33326f42765f33e4d5b28eb13e5f 1540 SUPERFAMILY SSF52151 534 667 1.1E-69 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CIG75_RS06615 9fdb33326f42765f33e4d5b28eb13e5f 1540 SUPERFAMILY SSF52151 727 821 1.1E-69 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CIG75_RS06615 9fdb33326f42765f33e4d5b28eb13e5f 1540 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1461 1476 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS06615 9fdb33326f42765f33e4d5b28eb13e5f 1540 Gene3D G3DSA:3.30.70.250 673 716 1.1E-17 T 28-03-2018 CIG75_RS06615 9fdb33326f42765f33e4d5b28eb13e5f 1540 SUPERFAMILY SSF47336 1429 1502 1.11E-20 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS06615 9fdb33326f42765f33e4d5b28eb13e5f 1540 Gene3D G3DSA:3.40.366.10 533 672 2.6E-46 T 28-03-2018 CIG75_RS06615 9fdb33326f42765f33e4d5b28eb13e5f 1540 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1133 1339 4.7E-18 T 28-03-2018 CIG75_RS06615 9fdb33326f42765f33e4d5b28eb13e5f 1540 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 390 499 3.5E-18 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS06615 9fdb33326f42765f33e4d5b28eb13e5f 1540 SMART SM00823 Phosphopantetheine attachment site 1437 1506 5.1E-8 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS06615 9fdb33326f42765f33e4d5b28eb13e5f 1540 Gene3D G3DSA:3.40.47.10 3 271 2.3E-72 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS06615 9fdb33326f42765f33e4d5b28eb13e5f 1540 Pfam PF00550 Phosphopantetheine attachment site 1439 1502 1.5E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS06615 9fdb33326f42765f33e4d5b28eb13e5f 1540 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 537 836 4.1E-105 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CIG75_RS06615 9fdb33326f42765f33e4d5b28eb13e5f 1540 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 12 260 4.5E-72 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CIG75_RS06615 9fdb33326f42765f33e4d5b28eb13e5f 1540 Gene3D G3DSA:1.10.1200.10 1420 1515 3.0E-23 T 28-03-2018 CIG75_RS06615 9fdb33326f42765f33e4d5b28eb13e5f 1540 SUPERFAMILY SSF55048 665 723 1.14E-9 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CIG75_RS06615 9fdb33326f42765f33e4d5b28eb13e5f 1540 Gene3D G3DSA:3.40.50.720 935 1041 0.14 T 28-03-2018 CIG75_RS06615 9fdb33326f42765f33e4d5b28eb13e5f 1540 Gene3D G3DSA:3.40.47.10 275 437 4.4E-55 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS06615 9fdb33326f42765f33e4d5b28eb13e5f 1540 Gene3D G3DSA:3.40.50.720 1125 1419 2.1E-21 T 28-03-2018 CIG75_RS06615 9fdb33326f42765f33e4d5b28eb13e5f 1540 Pfam PF08659 KR domain 1133 1338 1.5E-24 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS06615 9fdb33326f42765f33e4d5b28eb13e5f 1540 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 268 387 2.4E-39 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CIG75_RS03130 f2178a60ebd38ce43674ffee236ef194 1281 Gene3D G3DSA:1.10.287.700 856 962 5.9E-8 T 28-03-2018 CIG75_RS03130 f2178a60ebd38ce43674ffee236ef194 1281 Gene3D G3DSA:1.20.120.20 966 1071 6.2E-7 T 28-03-2018 CIG75_RS03130 f2178a60ebd38ce43674ffee236ef194 1281 Gene3D G3DSA:1.20.120.20 1072 1262 0.01 T 28-03-2018 CIG75_RS02070 e28717d998b9dc13e410a2c49d939c22 192 Gene3D G3DSA:1.10.10.10 106 192 2.4E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS02070 e28717d998b9dc13e410a2c49d939c22 192 Pfam PF04542 Sigma-70 region 2 26 94 1.3E-9 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS02070 e28717d998b9dc13e410a2c49d939c22 192 SUPERFAMILY SSF88659 108 189 1.74E-11 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS02070 e28717d998b9dc13e410a2c49d939c22 192 Gene3D G3DSA:1.10.1740.10 9 91 8.5E-15 T 28-03-2018 CIG75_RS02070 e28717d998b9dc13e410a2c49d939c22 192 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 186 3.4E-19 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS02070 e28717d998b9dc13e410a2c49d939c22 192 SUPERFAMILY SSF88946 6 90 1.44E-14 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS02070 e28717d998b9dc13e410a2c49d939c22 192 Pfam PF08281 Sigma-70, region 4 132 183 3.1E-10 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS07315 a98f77845af3788c75b6e7333031dfea 438 Gene3D G3DSA:1.10.260.40 2 85 8.4E-16 T 28-03-2018 CIG75_RS07315 a98f77845af3788c75b6e7333031dfea 438 Gene3D G3DSA:1.25.40.10 86 197 2.4E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS07315 a98f77845af3788c75b6e7333031dfea 438 Pfam PF01381 Helix-turn-helix 12 63 5.3E-10 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS07315 a98f77845af3788c75b6e7333031dfea 438 SUPERFAMILY SSF47413 5 69 2.11E-13 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CIG75_RS07315 a98f77845af3788c75b6e7333031dfea 438 SUPERFAMILY SSF48452 84 184 2.11E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS07315 a98f77845af3788c75b6e7333031dfea 438 SUPERFAMILY SSF48452 154 323 3.21E-15 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS07315 a98f77845af3788c75b6e7333031dfea 438 SMART SM00530 11 65 8.4E-11 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS07315 a98f77845af3788c75b6e7333031dfea 438 Gene3D G3DSA:1.25.40.10 238 433 1.4E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS07315 a98f77845af3788c75b6e7333031dfea 438 SMART SM00028 155 188 21.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS07315 a98f77845af3788c75b6e7333031dfea 438 SMART SM00028 196 229 15.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS07315 a98f77845af3788c75b6e7333031dfea 438 SMART SM00028 236 269 61.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS07315 a98f77845af3788c75b6e7333031dfea 438 Gene3D G3DSA:3.30.70.100 198 237 8.7E-5 T 28-03-2018 CIG75_RS06315 c8a9fb04a5276fb96e9d1fb18d266bc3 208 SUPERFAMILY SSF46929 161 207 4.05E-9 T 28-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 CIG75_RS06315 c8a9fb04a5276fb96e9d1fb18d266bc3 208 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 206 30.852 T 28-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 CIG75_RS06315 c8a9fb04a5276fb96e9d1fb18d266bc3 208 SUPERFAMILY SSF50249 2 62 4.45E-16 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CIG75_RS06315 c8a9fb04a5276fb96e9d1fb18d266bc3 208 Gene3D G3DSA:1.10.340.30 49 79 0.1 T 28-03-2018 CIG75_RS06315 c8a9fb04a5276fb96e9d1fb18d266bc3 208 Pfam PF07499 RuvA, C-terminal domain 161 206 5.2E-12 T 28-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 CIG75_RS06315 c8a9fb04a5276fb96e9d1fb18d266bc3 208 Gene3D G3DSA:2.40.50.140 1 48 3.9E-23 T 28-03-2018 CIG75_RS06315 c8a9fb04a5276fb96e9d1fb18d266bc3 208 Gene3D G3DSA:1.10.8.10 174 208 2.1E-11 T 28-03-2018 CIG75_RS06315 c8a9fb04a5276fb96e9d1fb18d266bc3 208 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 206 5.6E-57 T 28-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 CIG75_RS06315 c8a9fb04a5276fb96e9d1fb18d266bc3 208 SMART SM00278 107 126 0.04 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CIG75_RS06315 c8a9fb04a5276fb96e9d1fb18d266bc3 208 SMART SM00278 72 91 4.5 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CIG75_RS06315 c8a9fb04a5276fb96e9d1fb18d266bc3 208 Gene3D G3DSA:1.10.150.20 122 173 0.22 T 28-03-2018 CIG75_RS06315 c8a9fb04a5276fb96e9d1fb18d266bc3 208 SUPERFAMILY SSF47781 64 135 2.26E-21 T 28-03-2018 IPR010994 RuvA domain 2-like CIG75_RS06315 c8a9fb04a5276fb96e9d1fb18d266bc3 208 Gene3D G3DSA:1.10.150.20 80 121 1.9E-16 T 28-03-2018 CIG75_RS06315 c8a9fb04a5276fb96e9d1fb18d266bc3 208 Pfam PF14520 Helix-hairpin-helix domain 71 129 1.3E-17 T 28-03-2018 CIG75_RS06315 c8a9fb04a5276fb96e9d1fb18d266bc3 208 Pfam PF01330 RuvA N terminal domain 2 61 2.4E-20 T 28-03-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 CIG75_RS09835 58a35b6d0e3ad65c39b856ee1d688bd8 985 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 264 281 - T 28-03-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 CIG75_RS09835 58a35b6d0e3ad65c39b856ee1d688bd8 985 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 192 203 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CIG75_RS09835 58a35b6d0e3ad65c39b856ee1d688bd8 985 Gene3D G3DSA:3.30.70.20 129 210 5.9E-11 T 28-03-2018 CIG75_RS09835 58a35b6d0e3ad65c39b856ee1d688bd8 985 Gene3D G3DSA:3.40.50.740 317 514 1.1E-49 T 28-03-2018 CIG75_RS09835 58a35b6d0e3ad65c39b856ee1d688bd8 985 Gene3D G3DSA:3.10.20.30 1 125 5.7E-15 T 28-03-2018 IPR012675 Beta-grasp domain CIG75_RS09835 58a35b6d0e3ad65c39b856ee1d688bd8 985 Pfam PF00384 Molybdopterin oxidoreductase 316 739 1.1E-81 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CIG75_RS09835 58a35b6d0e3ad65c39b856ee1d688bd8 985 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 264 932 4.3E-257 T 28-03-2018 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.2.1.2|KEGG: 00680+1.2.1.2|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696 CIG75_RS09835 58a35b6d0e3ad65c39b856ee1d688bd8 985 SUPERFAMILY SSF54862 136 216 1.27E-16 T 28-03-2018 CIG75_RS09835 58a35b6d0e3ad65c39b856ee1d688bd8 985 SUPERFAMILY SSF54292 7 128 3.73E-31 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CIG75_RS09835 58a35b6d0e3ad65c39b856ee1d688bd8 985 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 4 78 1.3E-14 T 28-03-2018 CIG75_RS09835 58a35b6d0e3ad65c39b856ee1d688bd8 985 SUPERFAMILY SSF50692 788 934 2.94E-36 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain CIG75_RS09835 58a35b6d0e3ad65c39b856ee1d688bd8 985 PIRSF PIRSF036643 1 966 0.0 T 28-03-2018 CIG75_RS09835 58a35b6d0e3ad65c39b856ee1d688bd8 985 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 87 124 2.0E-10 T 28-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CIG75_RS09835 58a35b6d0e3ad65c39b856ee1d688bd8 985 Gene3D G3DSA:2.20.25.90 259 314 3.2E-19 T 28-03-2018 CIG75_RS09835 58a35b6d0e3ad65c39b856ee1d688bd8 985 SMART SM00926 259 313 2.3E-18 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CIG75_RS09835 58a35b6d0e3ad65c39b856ee1d688bd8 985 Pfam PF01568 Molydopterin dinucleotide binding domain 823 929 8.9E-23 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CIG75_RS09835 58a35b6d0e3ad65c39b856ee1d688bd8 985 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 260 313 1.3E-18 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CIG75_RS09835 58a35b6d0e3ad65c39b856ee1d688bd8 985 Pfam PF00037 4Fe-4S binding domain 186 207 1.5E-5 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CIG75_RS09835 58a35b6d0e3ad65c39b856ee1d688bd8 985 Gene3D G3DSA:2.40.40.20 783 935 1.7E-31 T 28-03-2018 CIG75_RS09835 58a35b6d0e3ad65c39b856ee1d688bd8 985 Gene3D G3DSA:3.40.50.740 515 782 9.5E-79 T 28-03-2018 CIG75_RS09835 58a35b6d0e3ad65c39b856ee1d688bd8 985 SUPERFAMILY SSF53706 253 776 4.45E-195 T 28-03-2018 CIG75_RS09835 58a35b6d0e3ad65c39b856ee1d688bd8 985 SMART SM00929 85 126 2.0E-11 T 28-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CIG75_RS18555 62d536a4c99c0e559178c989da0a3129 1034 Pfam PF00873 AcrB/AcrD/AcrF family 270 1023 8.8E-154 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CIG75_RS18555 62d536a4c99c0e559178c989da0a3129 1034 Pfam PF00873 AcrB/AcrD/AcrF family 4 245 9.9E-39 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CIG75_RS18555 62d536a4c99c0e559178c989da0a3129 1034 Gene3D G3DSA:1.20.1640.10 287 513 1.2E-44 T 28-03-2018 CIG75_RS18555 62d536a4c99c0e559178c989da0a3129 1034 Gene3D G3DSA:1.20.1640.10 812 1027 3.4E-42 T 28-03-2018 CIG75_RS18555 62d536a4c99c0e559178c989da0a3129 1034 PRINTS PR00702 Acriflavin resistance protein family signature 347 370 5.3E-46 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CIG75_RS18555 62d536a4c99c0e559178c989da0a3129 1034 PRINTS PR00702 Acriflavin resistance protein family signature 458 481 5.3E-46 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CIG75_RS18555 62d536a4c99c0e559178c989da0a3129 1034 PRINTS PR00702 Acriflavin resistance protein family signature 39 57 5.3E-46 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CIG75_RS18555 62d536a4c99c0e559178c989da0a3129 1034 PRINTS PR00702 Acriflavin resistance protein family signature 11 35 5.3E-46 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CIG75_RS18555 62d536a4c99c0e559178c989da0a3129 1034 PRINTS PR00702 Acriflavin resistance protein family signature 374 395 5.3E-46 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CIG75_RS18555 62d536a4c99c0e559178c989da0a3129 1034 PRINTS PR00702 Acriflavin resistance protein family signature 402 426 5.3E-46 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CIG75_RS18555 62d536a4c99c0e559178c989da0a3129 1034 PRINTS PR00702 Acriflavin resistance protein family signature 483 506 5.3E-46 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CIG75_RS18555 62d536a4c99c0e559178c989da0a3129 1034 SUPERFAMILY SSF82866 803 1028 1.57E-47 T 28-03-2018 CIG75_RS18555 62d536a4c99c0e559178c989da0a3129 1034 Gene3D G3DSA:3.30.2090.10 176 286 1.7E-13 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CIG75_RS18555 62d536a4c99c0e559178c989da0a3129 1034 Gene3D G3DSA:3.30.70.1430 569 671 3.5E-13 T 28-03-2018 CIG75_RS18555 62d536a4c99c0e559178c989da0a3129 1034 SUPERFAMILY SSF82693 41 127 1.57E-14 T 28-03-2018 CIG75_RS18555 62d536a4c99c0e559178c989da0a3129 1034 SUPERFAMILY SSF82693 287 339 6.98E-13 T 28-03-2018 CIG75_RS18555 62d536a4c99c0e559178c989da0a3129 1034 SUPERFAMILY SSF82693 134 177 6.98E-13 T 28-03-2018 CIG75_RS18555 62d536a4c99c0e559178c989da0a3129 1034 Gene3D G3DSA:3.30.70.1430 41 140 1.9E-17 T 28-03-2018 CIG75_RS18555 62d536a4c99c0e559178c989da0a3129 1034 SUPERFAMILY SSF82714 179 250 2.62E-8 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CIG75_RS18555 62d536a4c99c0e559178c989da0a3129 1034 SUPERFAMILY SSF82693 571 636 4.03E-6 T 28-03-2018 CIG75_RS18555 62d536a4c99c0e559178c989da0a3129 1034 Gene3D G3DSA:3.30.2090.10 721 806 1.8E-4 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CIG75_RS18555 62d536a4c99c0e559178c989da0a3129 1034 SUPERFAMILY SSF82866 309 510 1.06E-42 T 28-03-2018 CIG75_RS02815 e50f859f2053c71ddd940a92c4c14477 2374 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 546 840 1.5E-85 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CIG75_RS02815 e50f859f2053c71ddd940a92c4c14477 2374 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 11 259 1.2E-61 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CIG75_RS02815 e50f859f2053c71ddd940a92c4c14477 2374 Pfam PF00550 Phosphopantetheine attachment site 1755 1816 1.6E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS02815 e50f859f2053c71ddd940a92c4c14477 2374 SUPERFAMILY SSF52777 1936 2096 1.45E-15 T 28-03-2018 CIG75_RS02815 e50f859f2053c71ddd940a92c4c14477 2374 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 386 477 1.6E-14 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS02815 e50f859f2053c71ddd940a92c4c14477 2374 SUPERFAMILY SSF47336 1750 1817 4.06E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS02815 e50f859f2053c71ddd940a92c4c14477 2374 Gene3D G3DSA:3.40.366.10 542 682 5.1E-36 T 28-03-2018 CIG75_RS02815 e50f859f2053c71ddd940a92c4c14477 2374 SUPERFAMILY SSF55048 672 722 1.83E-5 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CIG75_RS02815 e50f859f2053c71ddd940a92c4c14477 2374 Gene3D G3DSA:3.40.47.10 2 271 4.8E-58 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS02815 e50f859f2053c71ddd940a92c4c14477 2374 SMART SM00823 Phosphopantetheine attachment site 1752 1820 6.3E-5 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS02815 e50f859f2053c71ddd940a92c4c14477 2374 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 172 188 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CIG75_RS02815 e50f859f2053c71ddd940a92c4c14477 2374 Pfam PF00698 Acyl transferase domain 545 825 2.6E-46 T 28-03-2018 IPR014043 Acyl transferase CIG75_RS02815 e50f859f2053c71ddd940a92c4c14477 2374 Gene3D G3DSA:3.40.50.150 1352 1573 8.6E-16 T 28-03-2018 CIG75_RS02815 e50f859f2053c71ddd940a92c4c14477 2374 SUPERFAMILY SSF53335 1369 1548 2.84E-22 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CIG75_RS02815 e50f859f2053c71ddd940a92c4c14477 2374 Gene3D G3DSA:1.10.1200.10 1747 1820 5.0E-18 T 28-03-2018 CIG75_RS02815 e50f859f2053c71ddd940a92c4c14477 2374 SUPERFAMILY SSF53901 155 380 2.24E-68 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS02815 e50f859f2053c71ddd940a92c4c14477 2374 SUPERFAMILY SSF53901 11 126 2.24E-68 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS02815 e50f859f2053c71ddd940a92c4c14477 2374 Gene3D G3DSA:3.30.559.10 1931 2102 2.1E-10 T 28-03-2018 CIG75_RS02815 e50f859f2053c71ddd940a92c4c14477 2374 SMART SM00825 Beta-ketoacyl synthase 12 444 3.1E-147 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CIG75_RS02815 e50f859f2053c71ddd940a92c4c14477 2374 Gene3D G3DSA:3.30.70.250 683 723 1.6E-12 T 28-03-2018 CIG75_RS02815 e50f859f2053c71ddd940a92c4c14477 2374 Gene3D G3DSA:3.40.47.10 275 442 1.4E-49 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS02815 e50f859f2053c71ddd940a92c4c14477 2374 Pfam PF00668 Condensation domain 1961 2110 2.8E-12 T 28-03-2018 IPR001242 Condensation domain CIG75_RS02815 e50f859f2053c71ddd940a92c4c14477 2374 Pfam PF08242 Methyltransferase domain 1391 1493 7.0E-11 T 28-03-2018 IPR013217 Methyltransferase type 12 CIG75_RS02815 e50f859f2053c71ddd940a92c4c14477 2374 SUPERFAMILY SSF52151 734 837 1.44E-61 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CIG75_RS02815 e50f859f2053c71ddd940a92c4c14477 2374 SUPERFAMILY SSF52151 543 673 1.44E-61 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CIG75_RS02815 e50f859f2053c71ddd940a92c4c14477 2374 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 267 383 7.3E-38 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CIG75_RS02815 e50f859f2053c71ddd940a92c4c14477 2374 Gene3D G3DSA:3.40.366.10 724 842 2.5E-22 T 28-03-2018 CIG75_RS13675 a1ad142247aaa165921255fae073e782 365 SMART SM00893 23 213 3.1E-42 T 28-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CIG75_RS13675 a1ad142247aaa165921255fae073e782 365 SUPERFAMILY SSF52402 22 201 6.77E-50 T 28-03-2018 CIG75_RS13675 a1ad142247aaa165921255fae073e782 365 PIRSF PIRSF000089 19 348 3.0E-113 T 28-03-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 CIG75_RS13675 a1ad142247aaa165921255fae073e782 365 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 287 313 - T 28-03-2018 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 CIG75_RS13675 a1ad142247aaa165921255fae073e782 365 Pfam PF01012 Electron transfer flavoprotein domain 23 201 2.2E-42 T 28-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CIG75_RS13675 a1ad142247aaa165921255fae073e782 365 Gene3D G3DSA:3.40.50.1220 219 349 1.5E-57 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CIG75_RS13675 a1ad142247aaa165921255fae073e782 365 Gene3D G3DSA:3.40.50.620 12 217 3.9E-50 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CIG75_RS13675 a1ad142247aaa165921255fae073e782 365 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 224 306 3.8E-36 T 28-03-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 CIG75_RS13675 a1ad142247aaa165921255fae073e782 365 SUPERFAMILY SSF52467 223 343 2.13E-48 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CIG75_RS10485 e97772a314f2a00c63cedb976f45b4aa 2277 Gene3D G3DSA:3.40.50.980 343 495 8.4E-36 T 28-03-2018 CIG75_RS10485 e97772a314f2a00c63cedb976f45b4aa 2277 SUPERFAMILY SSF56801 162 716 2.35E-151 T 28-03-2018 CIG75_RS10485 e97772a314f2a00c63cedb976f45b4aa 2277 Gene3D G3DSA:3.30.300.30 589 706 2.4E-39 T 28-03-2018 CIG75_RS10485 e97772a314f2a00c63cedb976f45b4aa 2277 Gene3D G3DSA:3.30.300.30 1633 1751 4.0E-37 T 28-03-2018 CIG75_RS10485 e97772a314f2a00c63cedb976f45b4aa 2277 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 217 618 6.7E-123 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS10485 e97772a314f2a00c63cedb976f45b4aa 2277 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1261 1662 1.3E-120 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS10485 e97772a314f2a00c63cedb976f45b4aa 2277 SMART SM00823 Phosphopantetheine attachment site 703 772 3.3E-7 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS10485 e97772a314f2a00c63cedb976f45b4aa 2277 SMART SM00823 Phosphopantetheine attachment site 1746 1815 1.2E-4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS10485 e97772a314f2a00c63cedb976f45b4aa 2277 SUPERFAMILY SSF52777 969 1212 1.11E-65 T 28-03-2018 CIG75_RS10485 e97772a314f2a00c63cedb976f45b4aa 2277 Gene3D G3DSA:2.30.38.10 1552 1631 1.9E-20 T 28-03-2018 CIG75_RS10485 e97772a314f2a00c63cedb976f45b4aa 2277 SUPERFAMILY SSF52777 8 166 1.45E-8 T 28-03-2018 CIG75_RS10485 e97772a314f2a00c63cedb976f45b4aa 2277 Pfam PF00668 Condensation domain 793 1222 1.6E-111 T 28-03-2018 IPR001242 Condensation domain CIG75_RS10485 e97772a314f2a00c63cedb976f45b4aa 2277 Pfam PF00668 Condensation domain 1832 2265 3.2E-110 T 28-03-2018 IPR001242 Condensation domain CIG75_RS10485 e97772a314f2a00c63cedb976f45b4aa 2277 Gene3D G3DSA:1.10.1200.10 1752 1813 3.8E-19 T 28-03-2018 CIG75_RS10485 e97772a314f2a00c63cedb976f45b4aa 2277 ProSitePatterns PS00455 Putative AMP-binding domain signature. 338 349 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS10485 e97772a314f2a00c63cedb976f45b4aa 2277 SUPERFAMILY SSF52777 794 961 2.56E-49 T 28-03-2018 CIG75_RS10485 e97772a314f2a00c63cedb976f45b4aa 2277 Gene3D G3DSA:3.40.50.980 188 342 3.2E-46 T 28-03-2018 CIG75_RS10485 e97772a314f2a00c63cedb976f45b4aa 2277 Gene3D G3DSA:3.40.50.980 1232 1388 1.8E-46 T 28-03-2018 CIG75_RS10485 e97772a314f2a00c63cedb976f45b4aa 2277 SUPERFAMILY SSF52777 2011 2257 8.12E-65 T 28-03-2018 CIG75_RS10485 e97772a314f2a00c63cedb976f45b4aa 2277 Pfam PF00550 Phosphopantetheine attachment site 705 767 6.5E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10485 e97772a314f2a00c63cedb976f45b4aa 2277 Pfam PF00550 Phosphopantetheine attachment site 1752 1811 2.6E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10485 e97772a314f2a00c63cedb976f45b4aa 2277 SUPERFAMILY SSF52777 1827 2025 1.45E-48 T 28-03-2018 CIG75_RS10485 e97772a314f2a00c63cedb976f45b4aa 2277 Pfam PF13193 AMP-binding enzyme C-terminal domain 602 678 3.1E-11 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS10485 e97772a314f2a00c63cedb976f45b4aa 2277 Pfam PF13193 AMP-binding enzyme C-terminal domain 1646 1719 3.0E-14 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS10485 e97772a314f2a00c63cedb976f45b4aa 2277 SUPERFAMILY SSF47336 1743 1811 7.33E-17 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10485 e97772a314f2a00c63cedb976f45b4aa 2277 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1770 1785 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS10485 e97772a314f2a00c63cedb976f45b4aa 2277 Gene3D G3DSA:1.10.1200.10 707 775 3.1E-20 T 28-03-2018 CIG75_RS10485 e97772a314f2a00c63cedb976f45b4aa 2277 Gene3D G3DSA:2.30.38.10 496 586 8.1E-20 T 28-03-2018 CIG75_RS10485 e97772a314f2a00c63cedb976f45b4aa 2277 Pfam PF00501 AMP-binding enzyme 1240 1638 2.0E-96 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS10485 e97772a314f2a00c63cedb976f45b4aa 2277 Pfam PF00501 AMP-binding enzyme 197 594 2.9E-99 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS10485 e97772a314f2a00c63cedb976f45b4aa 2277 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1382 1393 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS10485 e97772a314f2a00c63cedb976f45b4aa 2277 Gene3D G3DSA:3.30.559.10 1814 2027 2.4E-43 T 28-03-2018 CIG75_RS10485 e97772a314f2a00c63cedb976f45b4aa 2277 Gene3D G3DSA:3.30.559.10 776 984 9.0E-49 T 28-03-2018 CIG75_RS10485 e97772a314f2a00c63cedb976f45b4aa 2277 Gene3D G3DSA:3.40.50.980 1389 1549 1.7E-32 T 28-03-2018 CIG75_RS10485 e97772a314f2a00c63cedb976f45b4aa 2277 SUPERFAMILY SSF56801 1223 1758 3.66E-149 T 28-03-2018 CIG75_RS10485 e97772a314f2a00c63cedb976f45b4aa 2277 SUPERFAMILY SSF47336 695 804 5.89E-19 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS02050 6f98941c87a866efe09403707343eddd 269 Pfam PF00460 Flagella basal body rod protein 5 35 3.6E-7 T 28-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 CIG75_RS02050 6f98941c87a866efe09403707343eddd 269 SUPERFAMILY SSF117143 112 227 3.79E-6 T 28-03-2018 CIG75_RS02050 6f98941c87a866efe09403707343eddd 269 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 197 264 3.0E-16 T 28-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain CIG75_RS01940 e62cbaef37bea7c83384045b4293a8d0 291 PRINTS PR00126 ATP synthase gamma subunit signature 267 288 5.1E-36 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CIG75_RS01940 e62cbaef37bea7c83384045b4293a8d0 291 PRINTS PR00126 ATP synthase gamma subunit signature 236 255 5.1E-36 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CIG75_RS01940 e62cbaef37bea7c83384045b4293a8d0 291 PRINTS PR00126 ATP synthase gamma subunit signature 73 92 5.1E-36 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CIG75_RS01940 e62cbaef37bea7c83384045b4293a8d0 291 PRINTS PR00126 ATP synthase gamma subunit signature 164 181 5.1E-36 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CIG75_RS01940 e62cbaef37bea7c83384045b4293a8d0 291 Hamap MF_00815 ATP synthase gamma chain [atpG]. 1 289 36.16 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CIG75_RS01940 e62cbaef37bea7c83384045b4293a8d0 291 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 1 289 3.5E-106 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CIG75_RS01940 e62cbaef37bea7c83384045b4293a8d0 291 SUPERFAMILY SSF52943 2 289 4.84E-90 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CIG75_RS01940 e62cbaef37bea7c83384045b4293a8d0 291 Pfam PF00231 ATP synthase 3 289 8.0E-99 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CIG75_RS01940 e62cbaef37bea7c83384045b4293a8d0 291 Gene3D G3DSA:1.10.287.80 241 284 7.9E-12 T 28-03-2018 CIG75_RS01940 e62cbaef37bea7c83384045b4293a8d0 291 Gene3D G3DSA:1.10.287.80 2 41 5.5E-19 T 28-03-2018 CIG75_RS01940 e62cbaef37bea7c83384045b4293a8d0 291 Gene3D G3DSA:3.40.1380.10 42 240 6.5E-78 T 28-03-2018 CIG75_RS18300 6591626e7b70b1bd89bc51890f9f2d9e 249 Pfam PF13276 HTH-like domain 9 66 1.8E-17 T 28-03-2018 IPR025948 HTH-like domain CIG75_RS18300 6591626e7b70b1bd89bc51890f9f2d9e 249 Gene3D G3DSA:3.30.420.10 84 249 1.7E-33 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CIG75_RS18300 6591626e7b70b1bd89bc51890f9f2d9e 249 Pfam PF00665 Integrase core domain 89 202 2.7E-25 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CIG75_RS18300 6591626e7b70b1bd89bc51890f9f2d9e 249 SUPERFAMILY SSF53098 82 246 1.26E-36 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CIG75_RS10670 18f63637dc3691db47fe30d0de5a3c54 539 Gene3D G3DSA:1.20.1250.20 1 194 2.3E-35 T 28-03-2018 CIG75_RS10670 18f63637dc3691db47fe30d0de5a3c54 539 Gene3D G3DSA:1.20.1250.20 250 526 1.2E-38 T 28-03-2018 CIG75_RS10670 18f63637dc3691db47fe30d0de5a3c54 539 Pfam PF07690 Major Facilitator Superfamily 17 405 3.9E-46 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CIG75_RS10670 18f63637dc3691db47fe30d0de5a3c54 539 SUPERFAMILY SSF103473 5 189 9.16E-70 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS10670 18f63637dc3691db47fe30d0de5a3c54 539 SUPERFAMILY SSF103473 246 415 9.16E-70 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS10670 18f63637dc3691db47fe30d0de5a3c54 539 SUPERFAMILY SSF103473 486 511 9.16E-70 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS10670 18f63637dc3691db47fe30d0de5a3c54 539 ProSitePatterns PS00216 Sugar transport proteins signature 1. 65 81 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CIG75_RS10670 18f63637dc3691db47fe30d0de5a3c54 539 PRINTS PR01036 Tetracycline resistance protein TetB signature 74 96 1.6E-7 T 28-03-2018 CIG75_RS10670 18f63637dc3691db47fe30d0de5a3c54 539 PRINTS PR01036 Tetracycline resistance protein TetB signature 135 159 1.6E-7 T 28-03-2018 CIG75_RS10670 18f63637dc3691db47fe30d0de5a3c54 539 PRINTS PR01036 Tetracycline resistance protein TetB signature 15 39 1.6E-7 T 28-03-2018 CIG75_RS10670 18f63637dc3691db47fe30d0de5a3c54 539 PRINTS PR01036 Tetracycline resistance protein TetB signature 396 415 1.6E-7 T 28-03-2018 CIG75_RS07660 225d00ea05e1589341b52606fcce151f 386 PRINTS PR01272 Acetoin utilisation ACUC protein signature 352 371 4.4E-33 T 28-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 CIG75_RS07660 225d00ea05e1589341b52606fcce151f 386 PRINTS PR01272 Acetoin utilisation ACUC protein signature 88 102 4.4E-33 T 28-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 CIG75_RS07660 225d00ea05e1589341b52606fcce151f 386 PRINTS PR01272 Acetoin utilisation ACUC protein signature 335 351 4.4E-33 T 28-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 CIG75_RS07660 225d00ea05e1589341b52606fcce151f 386 PRINTS PR01272 Acetoin utilisation ACUC protein signature 18 38 4.4E-33 T 28-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 CIG75_RS07660 225d00ea05e1589341b52606fcce151f 386 PRINTS PR01272 Acetoin utilisation ACUC protein signature 315 334 4.4E-33 T 28-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 CIG75_RS07660 225d00ea05e1589341b52606fcce151f 386 PRINTS PR01272 Acetoin utilisation ACUC protein signature 109 122 4.4E-33 T 28-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 CIG75_RS07660 225d00ea05e1589341b52606fcce151f 386 PRINTS PR01272 Acetoin utilisation ACUC protein signature 276 292 4.4E-33 T 28-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 CIG75_RS07660 225d00ea05e1589341b52606fcce151f 386 SUPERFAMILY SSF52768 5 349 4.27E-110 T 28-03-2018 CIG75_RS07660 225d00ea05e1589341b52606fcce151f 386 Pfam PF00850 Histone deacetylase domain 24 320 3.8E-81 T 28-03-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CIG75_RS07660 225d00ea05e1589341b52606fcce151f 386 PRINTS PR01270 Histone deacetylase superfamily signature 165 180 3.9E-18 T 28-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CIG75_RS07660 225d00ea05e1589341b52606fcce151f 386 PRINTS PR01270 Histone deacetylase superfamily signature 251 261 3.9E-18 T 28-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CIG75_RS07660 225d00ea05e1589341b52606fcce151f 386 PRINTS PR01270 Histone deacetylase superfamily signature 132 155 3.9E-18 T 28-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CIG75_RS07660 225d00ea05e1589341b52606fcce151f 386 Gene3D G3DSA:3.40.800.20 5 349 3.6E-101 T 28-03-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CIG75_RS15165 c86851d685f53c614c80b756e7a29c90 586 Gene3D G3DSA:3.40.50.300 4 218 1.3E-60 T 28-03-2018 CIG75_RS15165 c86851d685f53c614c80b756e7a29c90 586 SUPERFAMILY SSF52540 71 356 1.64E-75 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS15165 c86851d685f53c614c80b756e7a29c90 586 Pfam PF00271 Helicase conserved C-terminal domain 227 335 4.8E-32 T 28-03-2018 IPR001650 Helicase, C-terminal CIG75_RS15165 c86851d685f53c614c80b756e7a29c90 586 Pfam PF00270 DEAD/DEAH box helicase 26 190 2.7E-51 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CIG75_RS15165 c86851d685f53c614c80b756e7a29c90 586 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 149 157 - T 28-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site CIG75_RS15165 c86851d685f53c614c80b756e7a29c90 586 SMART SM00487 21 218 4.5E-64 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CIG75_RS15165 c86851d685f53c614c80b756e7a29c90 586 SMART SM00490 254 335 1.2E-34 T 28-03-2018 IPR001650 Helicase, C-terminal CIG75_RS15165 c86851d685f53c614c80b756e7a29c90 586 Gene3D G3DSA:3.40.50.300 219 585 1.0E-48 T 28-03-2018 CIG75_RS11600 70717f84bec061639c64cf062cc7c598 448 Gene3D G3DSA:3.80.30.20 150 384 6.2E-53 T 28-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe CIG75_RS11600 70717f84bec061639c64cf062cc7c598 448 TIGRFAM TIGR01125 TIGR01125: ribosomal protein S12 methylthiotransferase RimO 8 445 5.0E-161 T 28-03-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 CIG75_RS11600 70717f84bec061639c64cf062cc7c598 448 SMART SM00729 152 370 1.3E-58 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CIG75_RS11600 70717f84bec061639c64cf062cc7c598 448 Pfam PF00919 Uncharacterized protein family UPF0004 8 107 1.0E-30 T 28-03-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 CIG75_RS11600 70717f84bec061639c64cf062cc7c598 448 Pfam PF04055 Radical SAM superfamily 157 327 8.6E-29 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CIG75_RS11600 70717f84bec061639c64cf062cc7c598 448 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 156 176 - T 28-03-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 CIG75_RS11600 70717f84bec061639c64cf062cc7c598 448 Pfam PF01938 TRAM domain 382 448 3.6E-7 T 28-03-2018 IPR002792 TRAM domain CIG75_RS11600 70717f84bec061639c64cf062cc7c598 448 Gene3D G3DSA:2.40.50.140 385 448 1.2E-17 T 28-03-2018 CIG75_RS11600 70717f84bec061639c64cf062cc7c598 448 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 8 445 4.6E-140 T 28-03-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 CIG75_RS11600 70717f84bec061639c64cf062cc7c598 448 Hamap MF_01865 Ribosomal protein S12 methylthiotransferase RimO [rimO]. 7 447 64.647 T 28-03-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 CIG75_RS11600 70717f84bec061639c64cf062cc7c598 448 SUPERFAMILY SSF102114 125 374 4.19E-63 T 28-03-2018 CIG75_RS05405 9bbb10adbd63d2da6631f44b1dcec7f4 321 Pfam PF10040 CRISPR-associated endoribonuclease Cas6 193 314 1.4E-16 T 28-03-2018 IPR019267 CRISPR-associated protein Cas6, C-terminal CIG75_RS19755 08d025546b31e00a9d375ae14efeac93 156 PIRSF PIRSF002122 5 156 2.4E-56 T 28-03-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 CIG75_RS19755 08d025546b31e00a9d375ae14efeac93 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 9.6E-66 T 28-03-2018 IPR023798 Ribosomal protein S7 domain CIG75_RS19755 08d025546b31e00a9d375ae14efeac93 156 Gene3D G3DSA:1.10.455.10 7 156 8.3E-60 T 28-03-2018 IPR023798 Ribosomal protein S7 domain CIG75_RS19755 08d025546b31e00a9d375ae14efeac93 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 6.8E-67 T 28-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 CIG75_RS19755 08d025546b31e00a9d375ae14efeac93 156 SUPERFAMILY SSF47973 1 149 2.35E-61 T 28-03-2018 IPR023798 Ribosomal protein S7 domain CIG75_RS19755 08d025546b31e00a9d375ae14efeac93 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 35.377 T 28-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 CIG75_RS03820 00eb9386961d7cc8324ac8d46e73be04 356 SUPERFAMILY SSF69318 109 203 3.53E-8 T 28-03-2018 CIG75_RS03820 00eb9386961d7cc8324ac8d46e73be04 356 Gene3D G3DSA:2.130.10.130 81 282 2.1E-5 T 28-03-2018 CIG75_RS13635 9e2576e62c3d1cfeaab50105becc1c54 612 Pfam PF00679 Elongation factor G C-terminus 399 481 2.2E-21 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CIG75_RS13635 9e2576e62c3d1cfeaab50105becc1c54 612 Pfam PF03144 Elongation factor Tu domain 2 221 290 1.3E-9 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CIG75_RS13635 9e2576e62c3d1cfeaab50105becc1c54 612 SUPERFAMILY SSF52540 3 208 9.33E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS13635 9e2576e62c3d1cfeaab50105becc1c54 612 SUPERFAMILY SSF54980 400 514 5.28E-27 T 28-03-2018 IPR035647 EF-G domain III/V-like CIG75_RS13635 9e2576e62c3d1cfeaab50105becc1c54 612 Gene3D G3DSA:2.40.50.250 484 574 7.1E-37 T 28-03-2018 CIG75_RS13635 9e2576e62c3d1cfeaab50105becc1c54 612 Gene3D G3DSA:3.40.50.300 1 69 3.6E-10 T 28-03-2018 CIG75_RS13635 9e2576e62c3d1cfeaab50105becc1c54 612 PRINTS PR00315 GTP-binding elongation factor signature 9 22 1.8E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CIG75_RS13635 9e2576e62c3d1cfeaab50105becc1c54 612 PRINTS PR00315 GTP-binding elongation factor signature 53 61 1.8E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CIG75_RS13635 9e2576e62c3d1cfeaab50105becc1c54 612 PRINTS PR00315 GTP-binding elongation factor signature 89 100 1.8E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CIG75_RS13635 9e2576e62c3d1cfeaab50105becc1c54 612 PRINTS PR00315 GTP-binding elongation factor signature 125 134 1.8E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CIG75_RS13635 9e2576e62c3d1cfeaab50105becc1c54 612 PRINTS PR00315 GTP-binding elongation factor signature 73 83 1.8E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CIG75_RS13635 9e2576e62c3d1cfeaab50105becc1c54 612 Gene3D G3DSA:3.30.70.870 304 403 1.0E-34 T 28-03-2018 CIG75_RS13635 9e2576e62c3d1cfeaab50105becc1c54 612 Gene3D G3DSA:3.40.50.300 70 190 5.4E-33 T 28-03-2018 CIG75_RS13635 9e2576e62c3d1cfeaab50105becc1c54 612 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 7 600 2.2E-295 T 28-03-2018 IPR006298 GTP-binding protein TypA GO:0005525 CIG75_RS13635 9e2576e62c3d1cfeaab50105becc1c54 612 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 46 61 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site CIG75_RS13635 9e2576e62c3d1cfeaab50105becc1c54 612 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 8 148 3.6E-26 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CIG75_RS13635 9e2576e62c3d1cfeaab50105becc1c54 612 Pfam PF00009 Elongation factor Tu GTP binding domain 7 198 1.0E-58 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CIG75_RS13635 9e2576e62c3d1cfeaab50105becc1c54 612 Gene3D G3DSA:3.30.70.240 404 481 1.2E-15 T 28-03-2018 CIG75_RS13635 9e2576e62c3d1cfeaab50105becc1c54 612 SUPERFAMILY SSF54980 304 389 1.22E-16 T 28-03-2018 IPR035647 EF-G domain III/V-like CIG75_RS13635 9e2576e62c3d1cfeaab50105becc1c54 612 SUPERFAMILY SSF50447 153 301 4.64E-30 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CIG75_RS13635 9e2576e62c3d1cfeaab50105becc1c54 612 Gene3D G3DSA:2.40.30.10 191 302 5.8E-21 T 28-03-2018 CIG75_RS03875 370905f5042cacfe3adf16eebe5c94f7 268 SUPERFAMILY SSF55073 98 176 4.71E-6 T 28-03-2018 IPR029787 Nucleotide cyclase CIG75_RS08200 b1e6b0d8a761cc20884995c42f06ef24 801 Gene3D G3DSA:1.10.390.10 398 549 4.2E-52 T 28-03-2018 CIG75_RS08200 b1e6b0d8a761cc20884995c42f06ef24 801 Gene3D G3DSA:2.60.120.380 550 671 1.9E-21 T 28-03-2018 CIG75_RS08200 b1e6b0d8a761cc20884995c42f06ef24 801 Pfam PF03413 Peptidase propeptide and YPEB domain 167 236 2.3E-5 T 28-03-2018 IPR025711 PepSY domain CIG75_RS08200 b1e6b0d8a761cc20884995c42f06ef24 801 Gene3D G3DSA:2.60.120.290 672 777 2.3E-8 T 28-03-2018 IPR000859 CUB domain CIG75_RS08200 b1e6b0d8a761cc20884995c42f06ef24 801 Gene3D G3DSA:3.10.170.10 246 397 2.5E-48 T 28-03-2018 CIG75_RS08200 b1e6b0d8a761cc20884995c42f06ef24 801 Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif 116 151 2.0E-10 T 28-03-2018 IPR011096 FTP domain CIG75_RS08200 b1e6b0d8a761cc20884995c42f06ef24 801 SUPERFAMILY SSF49854 685 770 2.36E-9 T 28-03-2018 IPR000859 CUB domain CIG75_RS08200 b1e6b0d8a761cc20884995c42f06ef24 801 SUPERFAMILY SSF55486 244 548 2.69E-98 T 28-03-2018 CIG75_RS08200 b1e6b0d8a761cc20884995c42f06ef24 801 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 396 548 3.9E-52 T 28-03-2018 IPR001570 Peptidase M4, C-terminal GO:0004222 CIG75_RS08200 b1e6b0d8a761cc20884995c42f06ef24 801 SUPERFAMILY SSF89260 555 655 7.19E-14 T 28-03-2018 CIG75_RS08200 b1e6b0d8a761cc20884995c42f06ef24 801 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 248 392 1.7E-46 T 28-03-2018 IPR013856 Peptidase M4 domain GO:0004222 CIG75_RS08200 b1e6b0d8a761cc20884995c42f06ef24 801 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 348 368 2.0E-28 T 28-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 CIG75_RS08200 b1e6b0d8a761cc20884995c42f06ef24 801 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 405 416 2.0E-28 T 28-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 CIG75_RS08200 b1e6b0d8a761cc20884995c42f06ef24 801 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 471 487 2.0E-28 T 28-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 CIG75_RS08200 b1e6b0d8a761cc20884995c42f06ef24 801 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 384 400 2.0E-28 T 28-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 CIG75_RS06665 e40c741614a8b69f76f60ee9986ab7ee 1143 Gene3D G3DSA:1.10.1200.10 1059 1133 1.1E-23 T 28-03-2018 CIG75_RS06665 e40c741614a8b69f76f60ee9986ab7ee 1143 Gene3D G3DSA:3.40.50.980 690 843 2.8E-31 T 28-03-2018 CIG75_RS06665 e40c741614a8b69f76f60ee9986ab7ee 1143 Pfam PF00668 Condensation domain 79 521 5.7E-115 T 28-03-2018 IPR001242 Condensation domain CIG75_RS06665 e40c741614a8b69f76f60ee9986ab7ee 1143 Pfam PF13193 AMP-binding enzyme C-terminal domain 950 1025 6.3E-15 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS06665 e40c741614a8b69f76f60ee9986ab7ee 1143 ProSitePatterns PS00455 Putative AMP-binding domain signature. 683 694 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS06665 e40c741614a8b69f76f60ee9986ab7ee 1143 PIRSF PIRSF001617 265 672 2.1E-20 T 28-03-2018 CIG75_RS06665 e40c741614a8b69f76f60ee9986ab7ee 1143 PIRSF PIRSF001617 659 993 3.1E-29 T 28-03-2018 CIG75_RS06665 e40c741614a8b69f76f60ee9986ab7ee 1143 PIRSF PIRSF001617 987 1142 2.1E-23 T 28-03-2018 CIG75_RS06665 e40c741614a8b69f76f60ee9986ab7ee 1143 Gene3D G3DSA:2.30.38.10 844 934 1.8E-22 T 28-03-2018 CIG75_RS06665 e40c741614a8b69f76f60ee9986ab7ee 1143 Gene3D G3DSA:3.30.300.30 937 1058 1.7E-44 T 28-03-2018 CIG75_RS06665 e40c741614a8b69f76f60ee9986ab7ee 1143 Gene3D G3DSA:3.40.50.980 532 689 5.4E-48 T 28-03-2018 CIG75_RS06665 e40c741614a8b69f76f60ee9986ab7ee 1143 SUPERFAMILY SSF56801 502 1066 1.44E-161 T 28-03-2018 CIG75_RS06665 e40c741614a8b69f76f60ee9986ab7ee 1143 SUPERFAMILY SSF47336 1045 1118 3.93E-20 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS06665 e40c741614a8b69f76f60ee9986ab7ee 1143 Pfam PF00550 Phosphopantetheine attachment site 1054 1118 9.5E-16 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS06665 e40c741614a8b69f76f60ee9986ab7ee 1143 SUPERFAMILY SSF52777 264 505 1.45E-61 T 28-03-2018 CIG75_RS06665 e40c741614a8b69f76f60ee9986ab7ee 1143 SUPERFAMILY SSF52777 80 257 2.11E-49 T 28-03-2018 CIG75_RS06665 e40c741614a8b69f76f60ee9986ab7ee 1143 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 562 966 2.6E-133 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS06665 e40c741614a8b69f76f60ee9986ab7ee 1143 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1077 1092 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS06665 e40c741614a8b69f76f60ee9986ab7ee 1143 Gene3D G3DSA:3.30.559.10 59 280 4.8E-43 T 28-03-2018 CIG75_RS06665 e40c741614a8b69f76f60ee9986ab7ee 1143 Pfam PF00501 AMP-binding enzyme 541 942 1.3E-95 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS06665 e40c741614a8b69f76f60ee9986ab7ee 1143 SMART SM00823 Phosphopantetheine attachment site 1053 1122 0.0023 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS11145 d47d9dd823f108b995d1373baf3c4773 392 Gene3D G3DSA:1.25.40.10 83 344 5.8E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS11145 d47d9dd823f108b995d1373baf3c4773 392 SUPERFAMILY SSF47413 10 79 1.16E-6 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CIG75_RS11145 d47d9dd823f108b995d1373baf3c4773 392 Gene3D G3DSA:1.10.260.40 16 82 1.1E-7 T 28-03-2018 CIG75_RS11145 d47d9dd823f108b995d1373baf3c4773 392 SUPERFAMILY SSF48452 121 311 3.34E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS05435 0164e2752c333c9b80f7700e40c5cfd2 289 Pfam PF03787 RAMP superfamily 50 218 1.5E-20 T 28-03-2018 IPR005537 CRISPR type III-associated RAMP protein CIG75_RS01625 0e2cf0a0354abbc9683061155f3beb3c 382 Gene3D G3DSA:1.10.540.10 1 118 6.8E-42 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CIG75_RS01625 0e2cf0a0354abbc9683061155f3beb3c 382 SUPERFAMILY SSF47203 229 381 1.29E-62 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CIG75_RS01625 0e2cf0a0354abbc9683061155f3beb3c 382 Gene3D G3DSA:1.20.140.10 219 382 6.9E-67 T 28-03-2018 CIG75_RS01625 0e2cf0a0354abbc9683061155f3beb3c 382 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 230 379 4.2E-54 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CIG75_RS01625 0e2cf0a0354abbc9683061155f3beb3c 382 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 218 2.2E-27 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CIG75_RS01625 0e2cf0a0354abbc9683061155f3beb3c 382 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 117 8.1E-40 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CIG75_RS01625 0e2cf0a0354abbc9683061155f3beb3c 382 PIRSF PIRSF016578 3 382 7.8E-22 T 28-03-2018 CIG75_RS01625 0e2cf0a0354abbc9683061155f3beb3c 382 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 337 356 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CIG75_RS01625 0e2cf0a0354abbc9683061155f3beb3c 382 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 124 136 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CIG75_RS01625 0e2cf0a0354abbc9683061155f3beb3c 382 Gene3D G3DSA:2.40.110.10 119 218 1.9E-39 T 28-03-2018 CIG75_RS01625 0e2cf0a0354abbc9683061155f3beb3c 382 SUPERFAMILY SSF56645 1 243 5.37E-93 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CIG75_RS12625 6b2964b643d415b8a95140920050de65 477 SUPERFAMILY SSF56176 3 216 1.26E-68 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CIG75_RS12625 6b2964b643d415b8a95140920050de65 477 Pfam PF01565 FAD binding domain 40 178 1.8E-38 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CIG75_RS12625 6b2964b643d415b8a95140920050de65 477 Gene3D G3DSA:3.30.43.10 2 92 6.5E-23 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CIG75_RS12625 6b2964b643d415b8a95140920050de65 477 Gene3D G3DSA:3.30.465.10 93 238 5.8E-37 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CIG75_RS12625 6b2964b643d415b8a95140920050de65 477 Gene3D G3DSA:1.10.45.10 417 456 1.8E-16 T 28-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 CIG75_RS12625 6b2964b643d415b8a95140920050de65 477 Pfam PF02913 FAD linked oxidases, C-terminal domain 216 455 4.4E-72 T 28-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 CIG75_RS12625 6b2964b643d415b8a95140920050de65 477 SUPERFAMILY SSF55103 219 459 3.27E-68 T 28-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CIG75_RS05685 825568ac795ea9a095e0cce6c80fdbaf 163 PIRSF PIRSF019083 1 163 1.4E-41 T 28-03-2018 IPR016747 Phosphotransbutyrylase CIG75_RS05685 825568ac795ea9a095e0cce6c80fdbaf 163 Pfam PF04892 VanZ like family 12 155 2.1E-17 T 28-03-2018 IPR006976 VanZ-like CIG75_RS06045 6e2f71151b92ebc215168ec6488a09f4 1068 Pfam PF00905 Penicillin binding protein transpeptidase domain 382 626 7.7E-28 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CIG75_RS06045 6e2f71151b92ebc215168ec6488a09f4 1068 SUPERFAMILY SSF56601 240 262 5.63E-95 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CIG75_RS06045 6e2f71151b92ebc215168ec6488a09f4 1068 SUPERFAMILY SSF56601 300 727 5.63E-95 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CIG75_RS06045 6e2f71151b92ebc215168ec6488a09f4 1068 Pfam PF00912 Transglycosylase 79 258 1.5E-55 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 CIG75_RS06045 6e2f71151b92ebc215168ec6488a09f4 1068 SUPERFAMILY SSF53955 68 283 1.46E-63 T 28-03-2018 IPR023346 Lysozyme-like domain CIG75_RS06045 6e2f71151b92ebc215168ec6488a09f4 1068 Gene3D G3DSA:1.10.3810.10 69 275 5.2E-66 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 CIG75_RS06045 6e2f71151b92ebc215168ec6488a09f4 1068 SUPERFAMILY SSF49265 977 1061 2.68E-9 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CIG75_RS06045 6e2f71151b92ebc215168ec6488a09f4 1068 Gene3D G3DSA:2.60.40.10 976 1068 1.5E-13 T 28-03-2018 IPR013783 Immunoglobulin-like fold CIG75_RS06045 6e2f71151b92ebc215168ec6488a09f4 1068 Gene3D G3DSA:2.60.40.10 790 879 8.8E-13 T 28-03-2018 IPR013783 Immunoglobulin-like fold CIG75_RS06045 6e2f71151b92ebc215168ec6488a09f4 1068 Gene3D G3DSA:3.40.710.10 281 715 1.9E-90 T 28-03-2018 CIG75_RS06045 6e2f71151b92ebc215168ec6488a09f4 1068 Gene3D G3DSA:2.60.40.10 880 964 2.9E-8 T 28-03-2018 IPR013783 Immunoglobulin-like fold CIG75_RS06045 6e2f71151b92ebc215168ec6488a09f4 1068 SMART SM00060 881 956 40.0 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CIG75_RS06045 6e2f71151b92ebc215168ec6488a09f4 1068 SMART SM00060 979 1055 9.7E-4 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CIG75_RS06045 6e2f71151b92ebc215168ec6488a09f4 1068 SMART SM00060 789 865 0.16 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CIG75_RS06045 6e2f71151b92ebc215168ec6488a09f4 1068 SUPERFAMILY SSF49265 791 961 1.48E-11 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CIG75_RS08020 d88e24c77f253e8e6330d8bdd071c443 885 Gene3D G3DSA:3.90.740.10 196 242 4.3E-17 T 28-03-2018 CIG75_RS08020 d88e24c77f253e8e6330d8bdd071c443 885 Gene3D G3DSA:1.10.730.10 516 807 1.7E-82 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CIG75_RS08020 d88e24c77f253e8e6330d8bdd071c443 885 SUPERFAMILY SSF50677 195 345 6.02E-64 T 28-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CIG75_RS08020 d88e24c77f253e8e6330d8bdd071c443 885 Gene3D G3DSA:3.40.50.620 287 515 6.4E-74 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CIG75_RS08020 d88e24c77f253e8e6330d8bdd071c443 885 Gene3D G3DSA:1.10.287.380 812 882 1.6E-27 T 28-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 CIG75_RS08020 d88e24c77f253e8e6330d8bdd071c443 885 PRINTS PR00986 Valyl-tRNA synthetase signature 349 362 3.5E-38 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CIG75_RS08020 d88e24c77f253e8e6330d8bdd071c443 885 PRINTS PR00986 Valyl-tRNA synthetase signature 479 497 3.5E-38 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CIG75_RS08020 d88e24c77f253e8e6330d8bdd071c443 885 PRINTS PR00986 Valyl-tRNA synthetase signature 234 251 3.5E-38 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CIG75_RS08020 d88e24c77f253e8e6330d8bdd071c443 885 PRINTS PR00986 Valyl-tRNA synthetase signature 40 51 3.5E-38 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CIG75_RS08020 d88e24c77f253e8e6330d8bdd071c443 885 PRINTS PR00986 Valyl-tRNA synthetase signature 448 469 3.5E-38 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CIG75_RS08020 d88e24c77f253e8e6330d8bdd071c443 885 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 47 58 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CIG75_RS08020 d88e24c77f253e8e6330d8bdd071c443 885 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 819 883 7.2E-24 T 28-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 CIG75_RS08020 d88e24c77f253e8e6330d8bdd071c443 885 SUPERFAMILY SSF47323 579 834 1.72E-72 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CIG75_RS08020 d88e24c77f253e8e6330d8bdd071c443 885 SUPERFAMILY SSF46589 819 883 9.42E-18 T 28-03-2018 IPR010978 tRNA-binding arm GO:0000166 CIG75_RS08020 d88e24c77f253e8e6330d8bdd071c443 885 SUPERFAMILY SSF52374 4 196 8.58E-150 T 28-03-2018 CIG75_RS08020 d88e24c77f253e8e6330d8bdd071c443 885 SUPERFAMILY SSF52374 344 577 8.58E-150 T 28-03-2018 CIG75_RS08020 d88e24c77f253e8e6330d8bdd071c443 885 Gene3D G3DSA:3.40.50.620 20 195 3.7E-28 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CIG75_RS08020 d88e24c77f253e8e6330d8bdd071c443 885 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 19 566 5.1E-225 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CIG75_RS08020 d88e24c77f253e8e6330d8bdd071c443 885 TIGRFAM TIGR00422 valS: valine--tRNA ligase 7 866 0.0 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CIG75_RS08020 d88e24c77f253e8e6330d8bdd071c443 885 Pfam PF08264 Anticodon-binding domain of tRNA 611 759 8.9E-45 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CIG75_RS08020 d88e24c77f253e8e6330d8bdd071c443 885 Hamap MF_02004 Valine--tRNA ligase [valS]. 6 884 16.285 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 SUPERFAMILY SSF52777 4450 4694 6.45E-63 T 28-03-2018 CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 Gene3D G3DSA:1.10.1200.10 3113 3175 1.4E-22 T 28-03-2018 CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 Gene3D G3DSA:1.10.1200.10 4179 4244 4.0E-23 T 28-03-2018 CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 Gene3D G3DSA:1.10.1200.10 2041 2115 1.5E-17 T 28-03-2018 CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 SUPERFAMILY SSF56801 4688 5248 2.75E-156 T 28-03-2018 CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 Gene3D G3DSA:3.30.70.250 1801 1846 2.7E-15 T 28-03-2018 CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 Gene3D G3DSA:2.30.38.10 3973 4053 6.9E-23 T 28-03-2018 CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 Gene3D G3DSA:2.30.38.10 5032 5112 1.2E-24 T 28-03-2018 CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 Gene3D G3DSA:2.30.38.10 2907 2987 5.3E-24 T 28-03-2018 CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 SMART SM00823 Phosphopantetheine attachment site 2046 2115 0.0013 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 SMART SM00823 Phosphopantetheine attachment site 1045 1114 4.8E-4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 SMART SM00823 Phosphopantetheine attachment site 5238 5304 3.7E-6 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 SMART SM00823 Phosphopantetheine attachment site 3104 3176 9.0E-8 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 SMART SM00823 Phosphopantetheine attachment site 4170 4242 1.7E-7 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1512 1614 7.2E-19 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 Gene3D G3DSA:3.40.366.10 1662 1800 8.7E-42 T 28-03-2018 CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 SUPERFAMILY SSF52151 1854 1948 5.49E-68 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 SUPERFAMILY SSF52151 1663 1791 5.49E-68 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 SUPERFAMILY SSF56801 474 1056 3.01E-158 T 28-03-2018 CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 Gene3D G3DSA:3.40.50.980 505 654 2.1E-39 T 28-03-2018 CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 ProSitePatterns PS00455 Putative AMP-binding domain signature. 3803 3814 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 Gene3D G3DSA:3.40.50.980 655 850 1.3E-52 T 28-03-2018 CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1137 1382 3.5E-67 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2616 3021 1.4E-123 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 3682 4087 2.3E-123 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 534 961 1.0E-134 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 4747 5145 1.1E-142 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 SUPERFAMILY SSF47336 2043 2146 2.88E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 SUPERFAMILY SSF52777 4265 4442 8.0E-50 T 28-03-2018 CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3131 3146 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 Gene3D G3DSA:3.40.366.10 1847 1970 1.9E-26 T 28-03-2018 CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 Gene3D G3DSA:1.10.1200.10 1049 1123 4.2E-17 T 28-03-2018 CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 SUPERFAMILY SSF47336 3099 3209 6.02E-20 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 SUPERFAMILY SSF47336 4165 4275 9.42E-20 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1666 1960 1.5E-107 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 SUPERFAMILY SSF56801 3622 4185 8.77E-162 T 28-03-2018 CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 Gene3D G3DSA:3.30.559.10 4245 4445 1.4E-42 T 28-03-2018 CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 ProSitePatterns PS00455 Putative AMP-binding domain signature. 675 686 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 SUPERFAMILY SSF52777 3199 3376 2.67E-48 T 28-03-2018 CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 SUPERFAMILY SSF52777 237 481 2.67E-61 T 28-03-2018 CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 Pfam PF13193 AMP-binding enzyme C-terminal domain 4071 4146 5.7E-13 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 Pfam PF13193 AMP-binding enzyme C-terminal domain 3005 3080 5.9E-13 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 Pfam PF13193 AMP-binding enzyme C-terminal domain 5130 5206 5.0E-11 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 Pfam PF13193 AMP-binding enzyme C-terminal domain 945 1018 4.3E-6 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 Pfam PF00550 Phosphopantetheine attachment site 1047 1109 3.5E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 Pfam PF00550 Phosphopantetheine attachment site 3110 3172 6.3E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 Pfam PF00550 Phosphopantetheine attachment site 4176 4238 2.7E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 Pfam PF00550 Phosphopantetheine attachment site 5237 5297 2.1E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 Pfam PF00550 Phosphopantetheine attachment site 2048 2111 2.0E-10 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 ProSitePatterns PS00455 Putative AMP-binding domain signature. 4868 4879 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 SUPERFAMILY SSF53901 1536 1557 1.81E-78 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 SUPERFAMILY SSF53901 1135 1504 1.81E-78 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 Pfam PF00698 Acyl transferase domain 1665 1962 1.3E-55 T 28-03-2018 IPR014043 Acyl transferase CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 Pfam PF00668 Condensation domain 2130 2575 1.5E-125 T 28-03-2018 IPR001242 Condensation domain CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 Pfam PF00668 Condensation domain 49 486 1.1E-109 T 28-03-2018 IPR001242 Condensation domain CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 Pfam PF00668 Condensation domain 4262 4705 1.2E-116 T 28-03-2018 IPR001242 Condensation domain CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 Pfam PF00668 Condensation domain 3196 3641 2.1E-125 T 28-03-2018 IPR001242 Condensation domain CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 SUPERFAMILY SSF47336 5227 5298 1.7E-18 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 SUPERFAMILY SSF47336 1039 1110 3.53E-16 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 SMART SM00825 Beta-ketoacyl synthase 1139 1561 1.5E-182 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 Gene3D G3DSA:1.10.1200.10 5241 5328 1.8E-23 T 28-03-2018 CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1390 1508 4.5E-41 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4197 4212 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 SUPERFAMILY SSF56801 2554 3119 1.44E-163 T 28-03-2018 CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 ProSitePatterns PS00012 Phosphopantetheine attachment site. 5259 5274 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 SUPERFAMILY SSF55048 1790 1853 9.55E-10 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 Gene3D G3DSA:3.30.559.10 25 250 2.5E-44 T 28-03-2018 CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 Gene3D G3DSA:3.30.559.10 3176 3398 2.8E-50 T 28-03-2018 CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 Gene3D G3DSA:3.30.559.10 2116 2333 1.5E-46 T 28-03-2018 CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 SUPERFAMILY SSF52777 2318 2582 3.34E-67 T 28-03-2018 CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 Gene3D G3DSA:3.30.300.30 2992 3112 3.2E-42 T 28-03-2018 CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 Gene3D G3DSA:3.30.300.30 4058 4178 1.6E-41 T 28-03-2018 CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 Gene3D G3DSA:3.30.300.30 5117 5240 2.3E-37 T 28-03-2018 CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 Gene3D G3DSA:3.30.300.30 932 1048 1.3E-30 T 28-03-2018 CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 Gene3D G3DSA:3.40.50.980 4718 4873 7.9E-49 T 28-03-2018 CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 Gene3D G3DSA:3.40.50.980 2586 2742 1.6E-45 T 28-03-2018 CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 Gene3D G3DSA:3.40.50.980 3652 3808 3.2E-45 T 28-03-2018 CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 SUPERFAMILY SSF52777 2135 2310 2.56E-51 T 28-03-2018 CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 SUPERFAMILY SSF52777 51 228 2.89E-52 T 28-03-2018 CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2737 2748 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1295 1311 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 Gene3D G3DSA:3.40.50.980 2743 2905 3.0E-34 T 28-03-2018 CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 Gene3D G3DSA:3.40.50.980 4874 5029 3.1E-33 T 28-03-2018 CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 Gene3D G3DSA:3.40.50.980 3809 3971 5.0E-35 T 28-03-2018 CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 Gene3D G3DSA:3.40.47.10 1130 1394 6.5E-66 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 Gene3D G3DSA:2.30.38.10 851 930 1.1E-24 T 28-03-2018 CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 Gene3D G3DSA:3.40.47.10 1398 1559 1.2E-58 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 Pfam PF00501 AMP-binding enzyme 514 937 1.6E-105 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 Pfam PF00501 AMP-binding enzyme 3661 4063 8.0E-93 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 Pfam PF00501 AMP-binding enzyme 4726 5122 1.6E-105 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 Pfam PF00501 AMP-binding enzyme 2595 2997 1.2E-93 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS09795 e017da34be82e1d872d2b955753919b0 5330 SUPERFAMILY SSF52777 3384 3648 1.03E-71 T 28-03-2018 CIG75_RS08795 ce7d8d82c90136259887db8e69d773ab 254 Gene3D G3DSA:1.10.10.580 182 250 5.5E-10 T 28-03-2018 CIG75_RS08795 ce7d8d82c90136259887db8e69d773ab 254 Hamap MF_01805 Segregation and condensation protein A [scpA]. 9 252 23.378 T 28-03-2018 IPR003768 Segregation and condensation protein A CIG75_RS08795 ce7d8d82c90136259887db8e69d773ab 254 Pfam PF02616 Segregation and condensation protein ScpA 26 249 3.6E-42 T 28-03-2018 IPR003768 Segregation and condensation protein A CIG75_RS13850 6c6c672ab7166378f2a67d03a604c1fc 277 Gene3D G3DSA:3.10.290.10 5 68 5.5E-19 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CIG75_RS13850 6c6c672ab7166378f2a67d03a604c1fc 277 Pfam PF01479 S4 domain 10 57 5.0E-11 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CIG75_RS13850 6c6c672ab7166378f2a67d03a604c1fc 277 TIGRFAM TIGR00478 tly: TlyA family rRNA methyltransferase/putative hemolysin 11 243 9.2E-89 T 28-03-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 CIG75_RS13850 6c6c672ab7166378f2a67d03a604c1fc 277 SMART SM00363 10 75 2.2E-11 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CIG75_RS13850 6c6c672ab7166378f2a67d03a604c1fc 277 Pfam PF01728 FtsJ-like methyltransferase 66 248 8.8E-21 T 28-03-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 CIG75_RS13850 6c6c672ab7166378f2a67d03a604c1fc 277 SUPERFAMILY SSF53335 61 249 8.06E-23 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CIG75_RS13850 6c6c672ab7166378f2a67d03a604c1fc 277 PIRSF PIRSF005578 5 268 3.8E-105 T 28-03-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 CIG75_RS13850 6c6c672ab7166378f2a67d03a604c1fc 277 SUPERFAMILY SSF55174 7 75 7.51E-14 T 28-03-2018 CIG75_RS13850 6c6c672ab7166378f2a67d03a604c1fc 277 Gene3D G3DSA:3.40.50.150 69 277 2.4E-64 T 28-03-2018 CIG75_RS19825 90bc888c216be52e2f79e5c82c0d7847 310 Gene3D G3DSA:3.30.1330.30 57 138 2.5E-19 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CIG75_RS19825 90bc888c216be52e2f79e5c82c0d7847 310 Pfam PF00588 SpoU rRNA Methylase family 160 300 2.9E-42 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CIG75_RS19825 90bc888c216be52e2f79e5c82c0d7847 310 SUPERFAMILY SSF55315 62 138 1.77E-17 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CIG75_RS19825 90bc888c216be52e2f79e5c82c0d7847 310 SUPERFAMILY SSF75217 131 307 3.27E-51 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CIG75_RS19825 90bc888c216be52e2f79e5c82c0d7847 310 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 68 306 8.3E-75 T 28-03-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 CIG75_RS19825 90bc888c216be52e2f79e5c82c0d7847 310 Gene3D G3DSA:3.40.1280.10 146 310 3.0E-52 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CIG75_RS19825 90bc888c216be52e2f79e5c82c0d7847 310 SMART SM00967 69 143 2.3E-23 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CIG75_RS19825 90bc888c216be52e2f79e5c82c0d7847 310 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 70 142 1.1E-22 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CIG75_RS19555 93c3d06b9c537e5b93a8673a21b7c035 360 Hamap MF_02040 Iron-sulfur cluster carrier protein. 102 345 32.335 T 28-03-2018 IPR019591 Mrp/NBP35 ATP-binding protein CIG75_RS19555 93c3d06b9c537e5b93a8673a21b7c035 360 Pfam PF01883 Iron-sulfur cluster assembly protein 4 69 2.4E-19 T 28-03-2018 IPR002744 MIP18 family-like CIG75_RS19555 93c3d06b9c537e5b93a8673a21b7c035 360 SUPERFAMILY SSF117916 1 91 7.85E-22 T 28-03-2018 IPR034904 Fe-S cluster assembly domain CIG75_RS19555 93c3d06b9c537e5b93a8673a21b7c035 360 Gene3D G3DSA:3.30.300.130 1 94 1.1E-20 T 28-03-2018 IPR034904 Fe-S cluster assembly domain CIG75_RS19555 93c3d06b9c537e5b93a8673a21b7c035 360 Gene3D G3DSA:3.40.50.300 97 322 3.1E-50 T 28-03-2018 CIG75_RS19555 93c3d06b9c537e5b93a8673a21b7c035 360 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 112 340 2.4E-79 T 28-03-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 CIG75_RS19555 93c3d06b9c537e5b93a8673a21b7c035 360 SUPERFAMILY SSF52540 111 347 9.88E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS08405 009e2ac991b89902d0b0ae40498e01a6 357 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 141 194 2.7E-7 T 28-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CIG75_RS08405 009e2ac991b89902d0b0ae40498e01a6 357 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 211 298 3.4E-9 T 28-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CIG75_RS08405 009e2ac991b89902d0b0ae40498e01a6 357 SMART SM00839 138 345 1.9E-76 T 28-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CIG75_RS08405 009e2ac991b89902d0b0ae40498e01a6 357 PIRSF PIRSF000188 1 347 7.6E-164 T 28-03-2018 IPR016211 Glutamate/phenylalanine/leucine/valine dehydrogenase, bacterial/archaeal GO:0016639|GO:0055114 CIG75_RS08405 009e2ac991b89902d0b0ae40498e01a6 357 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 16 125 9.2E-27 T 28-03-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CIG75_RS08405 009e2ac991b89902d0b0ae40498e01a6 357 Gene3D G3DSA:3.40.50.720 139 357 4.3E-40 T 28-03-2018 CIG75_RS08405 009e2ac991b89902d0b0ae40498e01a6 357 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 280 291 9.0E-22 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CIG75_RS08405 009e2ac991b89902d0b0ae40498e01a6 357 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 126 148 9.0E-22 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CIG75_RS08405 009e2ac991b89902d0b0ae40498e01a6 357 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 170 190 9.0E-22 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CIG75_RS08405 009e2ac991b89902d0b0ae40498e01a6 357 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 60 74 9.0E-22 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CIG75_RS08405 009e2ac991b89902d0b0ae40498e01a6 357 Gene3D G3DSA:3.40.50.10860 1 138 2.0E-51 T 28-03-2018 CIG75_RS08405 009e2ac991b89902d0b0ae40498e01a6 357 SUPERFAMILY SSF53223 4 138 3.2E-47 T 28-03-2018 CIG75_RS08405 009e2ac991b89902d0b0ae40498e01a6 357 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 68 81 - T 28-03-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CIG75_RS08405 009e2ac991b89902d0b0ae40498e01a6 357 SUPERFAMILY SSF51735 135 340 1.48E-58 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS03095 c26859f7e68cb9d02d24f12f5d769dd3 2142 SUPERFAMILY SSF52777 1698 1874 6.67E-49 T 28-03-2018 CIG75_RS03095 c26859f7e68cb9d02d24f12f5d769dd3 2142 SUPERFAMILY SSF47336 509 582 2.09E-16 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS03095 c26859f7e68cb9d02d24f12f5d769dd3 2142 Pfam PF13193 AMP-binding enzyme C-terminal domain 1511 1581 3.2E-12 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS03095 c26859f7e68cb9d02d24f12f5d769dd3 2142 Pfam PF13193 AMP-binding enzyme C-terminal domain 414 489 9.1E-14 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS03095 c26859f7e68cb9d02d24f12f5d769dd3 2142 SUPERFAMILY SSF52777 790 1038 5.45E-59 T 28-03-2018 CIG75_RS03095 c26859f7e68cb9d02d24f12f5d769dd3 2142 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 35 430 1.5E-128 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS03095 c26859f7e68cb9d02d24f12f5d769dd3 2142 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1138 1527 3.4E-127 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS03095 c26859f7e68cb9d02d24f12f5d769dd3 2142 Gene3D G3DSA:3.40.50.980 1262 1411 8.8E-26 T 28-03-2018 CIG75_RS03095 c26859f7e68cb9d02d24f12f5d769dd3 2142 Pfam PF00550 Phosphopantetheine attachment site 1611 1670 2.7E-9 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS03095 c26859f7e68cb9d02d24f12f5d769dd3 2142 Pfam PF00550 Phosphopantetheine attachment site 518 581 1.1E-10 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS03095 c26859f7e68cb9d02d24f12f5d769dd3 2142 ProSitePatterns PS00455 Putative AMP-binding domain signature. 153 164 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS03095 c26859f7e68cb9d02d24f12f5d769dd3 2142 Gene3D G3DSA:1.10.1200.10 1614 1677 2.0E-18 T 28-03-2018 CIG75_RS03095 c26859f7e68cb9d02d24f12f5d769dd3 2142 Gene3D G3DSA:3.40.50.980 1111 1261 7.1E-45 T 28-03-2018 CIG75_RS03095 c26859f7e68cb9d02d24f12f5d769dd3 2142 SUPERFAMILY SSF52777 1882 2127 1.11E-62 T 28-03-2018 CIG75_RS03095 c26859f7e68cb9d02d24f12f5d769dd3 2142 SUPERFAMILY SSF56801 9 529 3.27E-147 T 28-03-2018 CIG75_RS03095 c26859f7e68cb9d02d24f12f5d769dd3 2142 Gene3D G3DSA:3.40.50.980 5 156 1.5E-44 T 28-03-2018 CIG75_RS03095 c26859f7e68cb9d02d24f12f5d769dd3 2142 Gene3D G3DSA:3.30.559.10 1678 1894 1.1E-45 T 28-03-2018 CIG75_RS03095 c26859f7e68cb9d02d24f12f5d769dd3 2142 Pfam PF00501 AMP-binding enzyme 1117 1503 1.0E-92 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS03095 c26859f7e68cb9d02d24f12f5d769dd3 2142 Pfam PF00501 AMP-binding enzyme 14 406 1.0E-92 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS03095 c26859f7e68cb9d02d24f12f5d769dd3 2142 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1632 1647 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS03095 c26859f7e68cb9d02d24f12f5d769dd3 2142 Gene3D G3DSA:1.10.1200.10 522 585 3.8E-18 T 28-03-2018 CIG75_RS03095 c26859f7e68cb9d02d24f12f5d769dd3 2142 SUPERFAMILY SSF56801 1109 1620 7.59E-147 T 28-03-2018 CIG75_RS03095 c26859f7e68cb9d02d24f12f5d769dd3 2142 Pfam PF00668 Condensation domain 602 1055 2.2E-107 T 28-03-2018 IPR001242 Condensation domain CIG75_RS03095 c26859f7e68cb9d02d24f12f5d769dd3 2142 Pfam PF00668 Condensation domain 1692 2127 1.3E-112 T 28-03-2018 IPR001242 Condensation domain CIG75_RS03095 c26859f7e68cb9d02d24f12f5d769dd3 2142 Gene3D G3DSA:3.30.559.10 586 801 6.4E-37 T 28-03-2018 CIG75_RS03095 c26859f7e68cb9d02d24f12f5d769dd3 2142 SUPERFAMILY SSF52777 607 784 1.33E-44 T 28-03-2018 CIG75_RS03095 c26859f7e68cb9d02d24f12f5d769dd3 2142 Gene3D G3DSA:3.30.300.30 1498 1613 2.2E-35 T 28-03-2018 CIG75_RS03095 c26859f7e68cb9d02d24f12f5d769dd3 2142 Gene3D G3DSA:3.30.300.30 401 521 2.5E-38 T 28-03-2018 CIG75_RS03095 c26859f7e68cb9d02d24f12f5d769dd3 2142 Gene3D G3DSA:2.30.38.10 1414 1496 9.9E-26 T 28-03-2018 CIG75_RS03095 c26859f7e68cb9d02d24f12f5d769dd3 2142 Gene3D G3DSA:2.30.38.10 318 399 3.3E-22 T 28-03-2018 CIG75_RS03095 c26859f7e68cb9d02d24f12f5d769dd3 2142 SMART SM00823 Phosphopantetheine attachment site 1608 1665 0.16 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS03095 c26859f7e68cb9d02d24f12f5d769dd3 2142 SMART SM00823 Phosphopantetheine attachment site 516 585 0.019 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS03095 c26859f7e68cb9d02d24f12f5d769dd3 2142 ProSitePatterns PS00012 Phosphopantetheine attachment site. 540 555 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS03095 c26859f7e68cb9d02d24f12f5d769dd3 2142 SUPERFAMILY SSF47336 1601 1671 2.36E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS03095 c26859f7e68cb9d02d24f12f5d769dd3 2142 Gene3D G3DSA:3.40.50.980 157 308 3.0E-36 T 28-03-2018 CIG75_RS03095 c26859f7e68cb9d02d24f12f5d769dd3 2142 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1257 1268 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS11945 fb4bf91d3ebe8c39959799a36bdc4bd0 685 SUPERFAMILY SSF50341 550 684 2.22E-31 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CIG75_RS11945 fb4bf91d3ebe8c39959799a36bdc4bd0 685 Gene3D G3DSA:2.30.30.40 630 684 3.2E-20 T 28-03-2018 CIG75_RS11945 fb4bf91d3ebe8c39959799a36bdc4bd0 685 Gene3D G3DSA:1.20.120.160 1 142 1.4E-31 T 28-03-2018 CIG75_RS11945 fb4bf91d3ebe8c39959799a36bdc4bd0 685 SMART SM00073 3 100 1.9E-29 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CIG75_RS11945 fb4bf91d3ebe8c39959799a36bdc4bd0 685 SMART SM01231 303 363 4.3E-19 T 28-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 CIG75_RS11945 fb4bf91d3ebe8c39959799a36bdc4bd0 685 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 411 550 5.1E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS11945 fb4bf91d3ebe8c39959799a36bdc4bd0 685 Pfam PF01584 CheW-like domain 555 684 7.7E-26 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CIG75_RS11945 fb4bf91d3ebe8c39959799a36bdc4bd0 685 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 304 363 4.2E-15 T 28-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 CIG75_RS11945 fb4bf91d3ebe8c39959799a36bdc4bd0 685 SMART SM00260 543 684 1.2E-39 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CIG75_RS11945 fb4bf91d3ebe8c39959799a36bdc4bd0 685 Gene3D G3DSA:3.30.70.1110 168 247 1.1E-23 T 28-03-2018 IPR010808 Signal transduction histidine kinase, P2 response regulator-binding GO:0000155|GO:0000160|GO:0004673|GO:0006928 CIG75_RS11945 fb4bf91d3ebe8c39959799a36bdc4bd0 685 Pfam PF07194 P2 response regulator binding domain 169 248 1.4E-24 T 28-03-2018 IPR010808 Signal transduction histidine kinase, P2 response regulator-binding GO:0000155|GO:0000160|GO:0004673|GO:0006928 CIG75_RS11945 fb4bf91d3ebe8c39959799a36bdc4bd0 685 Gene3D G3DSA:1.10.287.560 303 364 7.0E-20 T 28-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 CIG75_RS11945 fb4bf91d3ebe8c39959799a36bdc4bd0 685 Gene3D G3DSA:2.40.50.180 574 629 4.2E-11 T 28-03-2018 CIG75_RS11945 fb4bf91d3ebe8c39959799a36bdc4bd0 685 SUPERFAMILY SSF55874 365 549 3.01E-41 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS11945 fb4bf91d3ebe8c39959799a36bdc4bd0 685 SUPERFAMILY SSF47226 2 127 9.16E-32 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CIG75_RS11945 fb4bf91d3ebe8c39959799a36bdc4bd0 685 PRINTS PR00344 Bacterial sensor protein C-terminal signature 453 467 1.2E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS11945 fb4bf91d3ebe8c39959799a36bdc4bd0 685 PRINTS PR00344 Bacterial sensor protein C-terminal signature 535 548 1.2E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS11945 fb4bf91d3ebe8c39959799a36bdc4bd0 685 PRINTS PR00344 Bacterial sensor protein C-terminal signature 511 529 1.2E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS11945 fb4bf91d3ebe8c39959799a36bdc4bd0 685 Gene3D G3DSA:3.30.565.10 365 552 1.9E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS11945 fb4bf91d3ebe8c39959799a36bdc4bd0 685 SUPERFAMILY SSF55052 166 249 2.3E-22 T 28-03-2018 IPR015162 CheY binding CIG75_RS11945 fb4bf91d3ebe8c39959799a36bdc4bd0 685 SUPERFAMILY SSF47384 304 364 5.49E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CIG75_RS11945 fb4bf91d3ebe8c39959799a36bdc4bd0 685 SMART SM00387 408 551 4.4E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS11945 fb4bf91d3ebe8c39959799a36bdc4bd0 685 Pfam PF01627 Hpt domain 5 95 1.7E-17 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CIG75_RS15515 9b00fe63d3fc34f73ffb8ceaf2574510 318 Pfam PF00753 Metallo-beta-lactamase superfamily 16 251 1.9E-24 T 28-03-2018 IPR001279 Metallo-beta-lactamase CIG75_RS15515 9b00fe63d3fc34f73ffb8ceaf2574510 318 SMART SM00849 16 234 1.3E-28 T 28-03-2018 IPR001279 Metallo-beta-lactamase CIG75_RS15515 9b00fe63d3fc34f73ffb8ceaf2574510 318 Gene3D G3DSA:3.60.15.10 1 262 1.5E-38 T 28-03-2018 IPR001279 Metallo-beta-lactamase CIG75_RS15515 9b00fe63d3fc34f73ffb8ceaf2574510 318 SUPERFAMILY SSF56281 3 306 2.75E-49 T 28-03-2018 IPR001279 Metallo-beta-lactamase CIG75_RS11585 aa2bdda06896eafbf997298e109ba340 526 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 148 156 - T 28-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site CIG75_RS11585 aa2bdda06896eafbf997298e109ba340 526 Gene3D G3DSA:3.40.50.300 218 473 1.4E-46 T 28-03-2018 CIG75_RS11585 aa2bdda06896eafbf997298e109ba340 526 SMART SM00487 21 217 7.3E-68 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CIG75_RS11585 aa2bdda06896eafbf997298e109ba340 526 Pfam PF00271 Helicase conserved C-terminal domain 226 334 7.3E-30 T 28-03-2018 IPR001650 Helicase, C-terminal CIG75_RS11585 aa2bdda06896eafbf997298e109ba340 526 Gene3D G3DSA:3.40.50.300 8 217 7.8E-62 T 28-03-2018 CIG75_RS11585 aa2bdda06896eafbf997298e109ba340 526 SUPERFAMILY SSF52540 69 356 3.29E-79 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS11585 aa2bdda06896eafbf997298e109ba340 526 Pfam PF00270 DEAD/DEAH box helicase 27 191 7.2E-51 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CIG75_RS11585 aa2bdda06896eafbf997298e109ba340 526 SMART SM00490 253 334 2.1E-35 T 28-03-2018 IPR001650 Helicase, C-terminal CIG75_RS11585 aa2bdda06896eafbf997298e109ba340 526 Pfam PF03880 DbpA RNA binding domain 446 516 1.8E-23 T 28-03-2018 IPR005580 DEAD box helicase DbpA/CsdA, RNA-binding domain CIG75_RS03025 ffa5ed2e59b22866ec6037d77e6862f1 375 Pfam PF12832 MFS_1 like family 6 355 1.9E-51 T 28-03-2018 IPR024989 Major facilitator superfamily associated domain CIG75_RS03025 ffa5ed2e59b22866ec6037d77e6862f1 375 Gene3D G3DSA:1.20.1250.20 3 183 2.7E-17 T 28-03-2018 CIG75_RS03025 ffa5ed2e59b22866ec6037d77e6862f1 375 SUPERFAMILY SSF103473 12 373 2.22E-40 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS03025 ffa5ed2e59b22866ec6037d77e6862f1 375 Gene3D G3DSA:1.20.1250.20 184 374 4.2E-19 T 28-03-2018 CIG75_RS02215 e49836539c29d4c20c15624f6e7107f8 413 Gene3D G3DSA:1.25.40.10 55 141 1.6E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS02215 e49836539c29d4c20c15624f6e7107f8 413 Pfam PF12895 Anaphase-promoting complex, cyclosome, subunit 3 74 132 2.5E-10 T 28-03-2018 CIG75_RS02215 e49836539c29d4c20c15624f6e7107f8 413 SMART SM00028 346 379 4.7 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS02215 e49836539c29d4c20c15624f6e7107f8 413 SMART SM00028 146 179 28.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS02215 e49836539c29d4c20c15624f6e7107f8 413 SMART SM00028 108 141 10.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS02215 e49836539c29d4c20c15624f6e7107f8 413 SMART SM00028 227 260 180.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS02215 e49836539c29d4c20c15624f6e7107f8 413 SMART SM00028 187 220 0.0043 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS02215 e49836539c29d4c20c15624f6e7107f8 413 SUPERFAMILY SSF48452 74 222 1.52E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS02215 e49836539c29d4c20c15624f6e7107f8 413 Gene3D G3DSA:1.25.40.10 196 411 2.2E-23 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS02215 e49836539c29d4c20c15624f6e7107f8 413 SMART SM00530 9 63 2.2E-12 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS02215 e49836539c29d4c20c15624f6e7107f8 413 SUPERFAMILY SSF48452 185 392 1.39E-21 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS02215 e49836539c29d4c20c15624f6e7107f8 413 Pfam PF01535 PPR repeat 280 296 0.76 T 28-03-2018 IPR002885 Pentatricopeptide repeat CIG75_RS02215 e49836539c29d4c20c15624f6e7107f8 413 Pfam PF12844 Helix-turn-helix domain 7 66 4.1E-9 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS02215 e49836539c29d4c20c15624f6e7107f8 413 Gene3D G3DSA:1.10.260.40 1 54 9.0E-17 T 28-03-2018 CIG75_RS02215 e49836539c29d4c20c15624f6e7107f8 413 SUPERFAMILY SSF47413 2 68 1.52E-14 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CIG75_RS02215 e49836539c29d4c20c15624f6e7107f8 413 Pfam PF13424 Tetratricopeptide repeat 145 215 1.7E-7 T 28-03-2018 CIG75_RS02215 e49836539c29d4c20c15624f6e7107f8 413 Gene3D G3DSA:1.10.150.160 142 195 1.6E-5 T 28-03-2018 CIG75_RS10250 f485575ca8a91b07d2b3eac00b063846 399 SMART SM00636 67 380 1.4E-4 T 28-03-2018 IPR011583 Chitinase II GO:0008061 CIG75_RS10250 f485575ca8a91b07d2b3eac00b063846 399 Gene3D G3DSA:3.20.20.80 71 399 3.9E-29 T 28-03-2018 CIG75_RS10250 f485575ca8a91b07d2b3eac00b063846 399 SMART SM00257 8 52 8.1E-8 T 28-03-2018 IPR018392 LysM domain CIG75_RS10250 f485575ca8a91b07d2b3eac00b063846 399 Pfam PF01476 LysM domain 10 52 3.6E-9 T 28-03-2018 IPR018392 LysM domain CIG75_RS10250 f485575ca8a91b07d2b3eac00b063846 399 Pfam PF00704 Glycosyl hydrolases family 18 167 378 3.3E-17 T 28-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 CIG75_RS10250 f485575ca8a91b07d2b3eac00b063846 399 SUPERFAMILY SSF51445 352 396 4.22E-26 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CIG75_RS10250 f485575ca8a91b07d2b3eac00b063846 399 SUPERFAMILY SSF51445 91 296 4.22E-26 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CIG75_RS10250 f485575ca8a91b07d2b3eac00b063846 399 SUPERFAMILY SSF54106 10 52 4.05E-7 T 28-03-2018 IPR018392 LysM domain CIG75_RS10250 f485575ca8a91b07d2b3eac00b063846 399 Gene3D G3DSA:3.10.350.10 2 56 5.4E-11 T 28-03-2018 CIG75_RS15315 3fd6ea88284099da54c880406b44c617 260 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 255 1.3E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CIG75_RS15315 3fd6ea88284099da54c880406b44c617 260 SUPERFAMILY SSF161098 66 252 1.96E-33 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CIG75_RS15315 3fd6ea88284099da54c880406b44c617 260 TIGRFAM TIGR01097 PhnE: phosphonate ABC transporter, permease protein PhnE 13 259 9.4E-85 T 28-03-2018 IPR005769 ABC transporter, permease PhnE/PtxC GO:0005887|GO:0015604|GO:0015716 CIG75_RS15315 3fd6ea88284099da54c880406b44c617 260 Gene3D G3DSA:1.10.3720.10 14 260 2.3E-28 T 28-03-2018 CIG75_RS12345 ed5fd1def9ef47bf85341e2cb17cf774 231 SMART SM00535 21 156 3.8E-59 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CIG75_RS12345 ed5fd1def9ef47bf85341e2cb17cf774 231 Pfam PF00035 Double-stranded RNA binding motif 162 224 1.1E-14 T 28-03-2018 IPR014720 Double-stranded RNA-binding domain CIG75_RS12345 ed5fd1def9ef47bf85341e2cb17cf774 231 SMART SM00358 162 229 4.7E-16 T 28-03-2018 IPR014720 Double-stranded RNA-binding domain CIG75_RS12345 ed5fd1def9ef47bf85341e2cb17cf774 231 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 10 224 3.2E-77 T 28-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 CIG75_RS12345 ed5fd1def9ef47bf85341e2cb17cf774 231 SUPERFAMILY SSF69065 6 164 7.85E-54 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CIG75_RS12345 ed5fd1def9ef47bf85341e2cb17cf774 231 Gene3D G3DSA:3.30.160.20 155 230 2.8E-19 T 28-03-2018 CIG75_RS12345 ed5fd1def9ef47bf85341e2cb17cf774 231 Gene3D G3DSA:1.10.1520.10 3 154 1.4E-46 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CIG75_RS12345 ed5fd1def9ef47bf85341e2cb17cf774 231 SUPERFAMILY SSF54768 118 229 1.02E-21 T 28-03-2018 CIG75_RS12345 ed5fd1def9ef47bf85341e2cb17cf774 231 Hamap MF_00104 Ribonuclease 3 [rnc]. 9 225 31.106 T 28-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 CIG75_RS12345 ed5fd1def9ef47bf85341e2cb17cf774 231 ProSitePatterns PS00517 Ribonuclease III family signature. 45 53 - T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CIG75_RS12345 ed5fd1def9ef47bf85341e2cb17cf774 231 Pfam PF14622 Ribonuclease-III-like 19 150 6.6E-36 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CIG75_RS17175 fd35dbb4765b39820d3c5c95493091fa 289 SUPERFAMILY SSF52540 7 161 1.91E-13 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS17175 fd35dbb4765b39820d3c5c95493091fa 289 PIRSF PIRSF005052 5 289 2.5E-107 T 28-03-2018 IPR005337 RapZ-like family GO:0005524 CIG75_RS17175 fd35dbb4765b39820d3c5c95493091fa 289 Gene3D G3DSA:3.40.50.300 5 164 6.2E-11 T 28-03-2018 CIG75_RS17175 fd35dbb4765b39820d3c5c95493091fa 289 Pfam PF03668 P-loop ATPase protein family 5 289 1.4E-111 T 28-03-2018 IPR005337 RapZ-like family GO:0005524 CIG75_RS17175 fd35dbb4765b39820d3c5c95493091fa 289 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 5 288 40.993 T 28-03-2018 IPR005337 RapZ-like family GO:0005524 CIG75_RS15770 7001561a4395f74826bdc0690eb5cb90 221 TIGRFAM TIGR03328 salvage_mtnB: methylthioribulose-1-phosphate dehydratase 17 209 4.3E-61 T 28-03-2018 IPR017714 Methylthioribulose-1-phosphate dehydratase GO:0005737|GO:0019509|GO:0046872 KEGG: 00270+4.2.1.109|KEGG: 00400+4.2.1.10|MetaCyc: PWY-4361|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|Reactome: R-HSA-1237112 CIG75_RS15770 7001561a4395f74826bdc0690eb5cb90 221 Hamap MF_01677 Methylthioribulose-1-phosphate dehydratase [mtnB]. 1 213 89.117 T 28-03-2018 IPR017714 Methylthioribulose-1-phosphate dehydratase GO:0005737|GO:0019509|GO:0046872 KEGG: 00270+4.2.1.109|KEGG: 00400+4.2.1.10|MetaCyc: PWY-4361|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|Reactome: R-HSA-1237112 CIG75_RS15770 7001561a4395f74826bdc0690eb5cb90 221 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 15 202 1.3E-34 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CIG75_RS15770 7001561a4395f74826bdc0690eb5cb90 221 Gene3D G3DSA:3.40.225.10 8 219 5.5E-41 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CIG75_RS15770 7001561a4395f74826bdc0690eb5cb90 221 SMART SM01007 15 205 1.2E-33 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CIG75_RS15770 7001561a4395f74826bdc0690eb5cb90 221 SUPERFAMILY SSF53639 12 213 4.12E-38 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CIG75_RS10615 2393327567ef61b686f9d48173838ee6 2310 SUPERFAMILY SSF47336 1792 1865 6.15E-21 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10615 2393327567ef61b686f9d48173838ee6 2310 SUPERFAMILY SSF52777 844 1034 1.22E-42 T 28-03-2018 CIG75_RS10615 2393327567ef61b686f9d48173838ee6 2310 Gene3D G3DSA:3.40.50.980 1445 1603 2.0E-37 T 28-03-2018 CIG75_RS10615 2393327567ef61b686f9d48173838ee6 2310 Pfam PF13193 AMP-binding enzyme C-terminal domain 1700 1773 1.5E-10 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS10615 2393327567ef61b686f9d48173838ee6 2310 SMART SM00823 Phosphopantetheine attachment site 1800 1869 0.0015 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS10615 2393327567ef61b686f9d48173838ee6 2310 SUPERFAMILY SSF52777 2057 2299 3.34E-49 T 28-03-2018 CIG75_RS10615 2393327567ef61b686f9d48173838ee6 2310 Gene3D G3DSA:2.30.38.10 1604 1682 2.4E-24 T 28-03-2018 CIG75_RS10615 2393327567ef61b686f9d48173838ee6 2310 Gene3D G3DSA:3.30.559.10 1865 2070 2.0E-32 T 28-03-2018 CIG75_RS10615 2393327567ef61b686f9d48173838ee6 2310 Gene3D G3DSA:3.30.559.10 833 1037 3.0E-40 T 28-03-2018 CIG75_RS10615 2393327567ef61b686f9d48173838ee6 2310 Gene3D G3DSA:3.40.47.10 3 264 4.6E-68 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS10615 2393327567ef61b686f9d48173838ee6 2310 Gene3D G3DSA:1.10.1200.10 745 832 8.1E-6 T 28-03-2018 CIG75_RS10615 2393327567ef61b686f9d48173838ee6 2310 Pfam PF00550 Phosphopantetheine attachment site 1802 1863 1.6E-16 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10615 2393327567ef61b686f9d48173838ee6 2310 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 260 379 6.8E-38 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CIG75_RS10615 2393327567ef61b686f9d48173838ee6 2310 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 165 181 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CIG75_RS10615 2393327567ef61b686f9d48173838ee6 2310 SUPERFAMILY SSF52777 1021 1263 1.09E-60 T 28-03-2018 CIG75_RS10615 2393327567ef61b686f9d48173838ee6 2310 SUPERFAMILY SSF56801 1259 1813 9.29E-162 T 28-03-2018 CIG75_RS10615 2393327567ef61b686f9d48173838ee6 2310 SUPERFAMILY SSF47336 780 856 3.4E-6 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10615 2393327567ef61b686f9d48173838ee6 2310 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 381 475 4.8E-12 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS10615 2393327567ef61b686f9d48173838ee6 2310 SUPERFAMILY SSF53901 7 369 1.33E-73 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS10615 2393327567ef61b686f9d48173838ee6 2310 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1321 1716 2.9E-133 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS10615 2393327567ef61b686f9d48173838ee6 2310 Gene3D G3DSA:3.40.47.10 268 428 3.9E-48 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS10615 2393327567ef61b686f9d48173838ee6 2310 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 11 252 3.0E-67 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CIG75_RS10615 2393327567ef61b686f9d48173838ee6 2310 SMART SM00825 Beta-ketoacyl synthase 13 430 1.2E-130 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CIG75_RS10615 2393327567ef61b686f9d48173838ee6 2310 Gene3D G3DSA:3.40.50.980 1291 1444 1.6E-48 T 28-03-2018 CIG75_RS10615 2393327567ef61b686f9d48173838ee6 2310 Gene3D G3DSA:1.10.1200.10 1806 1864 1.6E-23 T 28-03-2018 CIG75_RS10615 2393327567ef61b686f9d48173838ee6 2310 Pfam PF00668 Condensation domain 1883 2304 2.1E-94 T 28-03-2018 IPR001242 Condensation domain CIG75_RS10615 2393327567ef61b686f9d48173838ee6 2310 Pfam PF00668 Condensation domain 847 1279 3.5E-123 T 28-03-2018 IPR001242 Condensation domain CIG75_RS10615 2393327567ef61b686f9d48173838ee6 2310 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1439 1450 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS10615 2393327567ef61b686f9d48173838ee6 2310 Gene3D G3DSA:3.30.300.30 1687 1805 1.7E-39 T 28-03-2018 CIG75_RS10615 2393327567ef61b686f9d48173838ee6 2310 Pfam PF00501 AMP-binding enzyme 1300 1692 8.4E-104 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS10615 2393327567ef61b686f9d48173838ee6 2310 SUPERFAMILY SSF52777 1886 2070 5.89E-33 T 28-03-2018 CIG75_RS08930 4e973f7ab160f71476fb847f03ecb6c3 230 Pfam PF02146 Sir2 family 34 195 1.7E-26 T 28-03-2018 IPR003000 Sirtuin family GO:0070403 CIG75_RS08930 4e973f7ab160f71476fb847f03ecb6c3 230 Gene3D G3DSA:3.40.50.1220 156 221 2.7E-12 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CIG75_RS08930 4e973f7ab160f71476fb847f03ecb6c3 230 Gene3D G3DSA:3.30.1600.10 17 91 6.0E-4 T 28-03-2018 IPR026591 Sirtuin family, catalytic core small domain CIG75_RS08930 4e973f7ab160f71476fb847f03ecb6c3 230 SUPERFAMILY SSF52467 30 220 1.45E-50 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CIG75_RS08930 4e973f7ab160f71476fb847f03ecb6c3 230 Gene3D G3DSA:3.30.1600.10 92 155 5.5E-15 T 28-03-2018 IPR026591 Sirtuin family, catalytic core small domain CIG75_RS06535 0bb75c58cb42d8f40e47e4a4df2a70bd 257 SUPERFAMILY SSF51735 4 256 1.46E-79 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS06535 0bb75c58cb42d8f40e47e4a4df2a70bd 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 4.2E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS06535 0bb75c58cb42d8f40e47e4a4df2a70bd 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 4.2E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS06535 0bb75c58cb42d8f40e47e4a4df2a70bd 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 4.2E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS06535 0bb75c58cb42d8f40e47e4a4df2a70bd 257 TIGRFAM TIGR01963 PHB_DH: 3-hydroxybutyrate dehydrogenase 4 257 1.4E-109 T 28-03-2018 IPR011294 3-hydroxybutyrate dehydrogenase GO:0003858|GO:0055114 CIG75_RS06535 0bb75c58cb42d8f40e47e4a4df2a70bd 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 2.4E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS06535 0bb75c58cb42d8f40e47e4a4df2a70bd 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 2.4E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS06535 0bb75c58cb42d8f40e47e4a4df2a70bd 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 218 238 2.4E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS06535 0bb75c58cb42d8f40e47e4a4df2a70bd 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 2.4E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS06535 0bb75c58cb42d8f40e47e4a4df2a70bd 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 2.4E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS06535 0bb75c58cb42d8f40e47e4a4df2a70bd 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 2.4E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS06535 0bb75c58cb42d8f40e47e4a4df2a70bd 257 Gene3D G3DSA:3.40.50.720 1 39 1.2E-8 T 28-03-2018 CIG75_RS06535 0bb75c58cb42d8f40e47e4a4df2a70bd 257 Gene3D G3DSA:3.40.50.720 40 257 1.5E-60 T 28-03-2018 CIG75_RS06535 0bb75c58cb42d8f40e47e4a4df2a70bd 257 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 10 255 5.2E-62 T 28-03-2018 CIG75_RS06535 0bb75c58cb42d8f40e47e4a4df2a70bd 257 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4 183 0.0046 T 28-03-2018 CIG75_RS06535 0bb75c58cb42d8f40e47e4a4df2a70bd 257 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CIG75_RS09725 ed17e6ece6d3e586d26766ade6a6785a 468 SUPERFAMILY SSF53756 2 66 8.97E-65 T 28-03-2018 CIG75_RS09725 ed17e6ece6d3e586d26766ade6a6785a 468 SUPERFAMILY SSF53756 136 464 8.97E-65 T 28-03-2018 CIG75_RS09725 ed17e6ece6d3e586d26766ade6a6785a 468 Gene3D G3DSA:3.40.50.2000 284 457 2.1E-36 T 28-03-2018 CIG75_RS09725 ed17e6ece6d3e586d26766ade6a6785a 468 Gene3D G3DSA:3.40.50.2000 118 283 1.3E-8 T 28-03-2018 CIG75_RS09725 ed17e6ece6d3e586d26766ade6a6785a 468 Pfam PF00534 Glycosyl transferases group 1 277 443 4.1E-26 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CIG75_RS09725 ed17e6ece6d3e586d26766ade6a6785a 468 Pfam PF11997 Domain of unknown function (DUF3492) 2 255 1.8E-70 T 28-03-2018 IPR022622 Domain of unknown function DUF3492 CIG75_RS06650 f525f8de7a39de4f02830e83105c8e10 1529 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1450 1465 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS06650 f525f8de7a39de4f02830e83105c8e10 1529 Gene3D G3DSA:3.40.47.10 2 266 8.7E-71 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS06650 f525f8de7a39de4f02830e83105c8e10 1529 Pfam PF00550 Phosphopantetheine attachment site 1428 1491 8.2E-16 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS06650 f525f8de7a39de4f02830e83105c8e10 1529 SUPERFAMILY SSF55048 660 720 1.83E-9 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CIG75_RS06650 f525f8de7a39de4f02830e83105c8e10 1529 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 383 494 2.8E-20 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS06650 f525f8de7a39de4f02830e83105c8e10 1529 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 262 381 4.6E-41 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CIG75_RS06650 f525f8de7a39de4f02830e83105c8e10 1529 SMART SM00825 Beta-ketoacyl synthase 10 434 1.1E-185 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CIG75_RS06650 f525f8de7a39de4f02830e83105c8e10 1529 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 10 254 7.6E-72 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CIG75_RS06650 f525f8de7a39de4f02830e83105c8e10 1529 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 167 183 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CIG75_RS06650 f525f8de7a39de4f02830e83105c8e10 1529 SUPERFAMILY SSF53901 409 430 2.49E-81 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS06650 f525f8de7a39de4f02830e83105c8e10 1529 SUPERFAMILY SSF53901 150 376 2.49E-81 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS06650 f525f8de7a39de4f02830e83105c8e10 1529 SUPERFAMILY SSF53901 7 121 2.49E-81 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS06650 f525f8de7a39de4f02830e83105c8e10 1529 Gene3D G3DSA:3.30.70.250 673 714 1.3E-18 T 28-03-2018 CIG75_RS06650 f525f8de7a39de4f02830e83105c8e10 1529 Pfam PF08659 KR domain 1137 1333 4.6E-41 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS06650 f525f8de7a39de4f02830e83105c8e10 1529 SMART SM00823 Phosphopantetheine attachment site 1426 1495 4.6E-9 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS06650 f525f8de7a39de4f02830e83105c8e10 1529 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 532 831 4.0E-101 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CIG75_RS06650 f525f8de7a39de4f02830e83105c8e10 1529 Gene3D G3DSA:3.40.366.10 715 835 1.5E-24 T 28-03-2018 CIG75_RS06650 f525f8de7a39de4f02830e83105c8e10 1529 Pfam PF00698 Acyl transferase domain 531 853 3.9E-54 T 28-03-2018 IPR014043 Acyl transferase CIG75_RS06650 f525f8de7a39de4f02830e83105c8e10 1529 Gene3D G3DSA:3.40.47.10 270 432 1.4E-58 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS06650 f525f8de7a39de4f02830e83105c8e10 1529 SUPERFAMILY SSF51735 901 1124 1.31E-26 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS06650 f525f8de7a39de4f02830e83105c8e10 1529 Gene3D G3DSA:3.40.366.10 528 672 5.3E-44 T 28-03-2018 CIG75_RS06650 f525f8de7a39de4f02830e83105c8e10 1529 Gene3D G3DSA:3.40.50.720 1129 1411 1.5E-39 T 28-03-2018 CIG75_RS06650 f525f8de7a39de4f02830e83105c8e10 1529 Gene3D G3DSA:3.40.50.720 932 1120 0.094 T 28-03-2018 CIG75_RS06650 f525f8de7a39de4f02830e83105c8e10 1529 SUPERFAMILY SSF47336 1418 1492 3.4E-20 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS06650 f525f8de7a39de4f02830e83105c8e10 1529 SUPERFAMILY SSF52151 529 662 1.75E-66 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CIG75_RS06650 f525f8de7a39de4f02830e83105c8e10 1529 SUPERFAMILY SSF52151 722 821 1.75E-66 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CIG75_RS06650 f525f8de7a39de4f02830e83105c8e10 1529 SUPERFAMILY SSF51735 1134 1354 1.26E-29 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS06650 f525f8de7a39de4f02830e83105c8e10 1529 Gene3D G3DSA:1.10.1200.10 1412 1504 4.6E-23 T 28-03-2018 CIG75_RS06650 f525f8de7a39de4f02830e83105c8e10 1529 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1137 1335 1.2E-31 T 28-03-2018 CIG75_RS12000 98b2a7748c458411c9fdf9f0784e7e57 441 Gene3D G3DSA:2.30.330.10 348 441 1.3E-28 T 28-03-2018 IPR001543 Surface presentation of antigen (SpoA) CIG75_RS12000 98b2a7748c458411c9fdf9f0784e7e57 441 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 361 431 1.6E-23 T 28-03-2018 IPR001543 Surface presentation of antigen (SpoA) CIG75_RS12000 98b2a7748c458411c9fdf9f0784e7e57 441 TIGRFAM TIGR02480 fliN: flagellar motor switch protein FliN 358 433 1.6E-30 T 28-03-2018 IPR012826 Flagellar motor switch FliN GO:0006935|GO:0009288|GO:0016020|GO:0071973 CIG75_RS12000 98b2a7748c458411c9fdf9f0784e7e57 441 Pfam PF04509 CheC-like family 134 169 8.3E-12 T 28-03-2018 IPR007597 CheC-like protein GO:0016787 CIG75_RS12000 98b2a7748c458411c9fdf9f0784e7e57 441 Pfam PF04509 CheC-like family 39 73 3.7E-13 T 28-03-2018 IPR007597 CheC-like protein GO:0016787 CIG75_RS12000 98b2a7748c458411c9fdf9f0784e7e57 441 SUPERFAMILY SSF103039 32 222 4.91E-49 T 28-03-2018 IPR028976 CheC-like domain CIG75_RS12000 98b2a7748c458411c9fdf9f0784e7e57 441 PRINTS PR00956 Flagellar motor switch protein FliN signature 394 407 9.5E-27 T 28-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 CIG75_RS12000 98b2a7748c458411c9fdf9f0784e7e57 441 PRINTS PR00956 Flagellar motor switch protein FliN signature 407 422 9.5E-27 T 28-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 CIG75_RS12000 98b2a7748c458411c9fdf9f0784e7e57 441 PRINTS PR00956 Flagellar motor switch protein FliN signature 361 377 9.5E-27 T 28-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 CIG75_RS12000 98b2a7748c458411c9fdf9f0784e7e57 441 PRINTS PR00956 Flagellar motor switch protein FliN signature 378 394 9.5E-27 T 28-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 CIG75_RS12000 98b2a7748c458411c9fdf9f0784e7e57 441 Gene3D G3DSA:3.40.1550.10 82 210 9.2E-35 T 28-03-2018 IPR028976 CheC-like domain CIG75_RS12000 98b2a7748c458411c9fdf9f0784e7e57 441 SUPERFAMILY SSF101801 358 439 4.05E-24 T 28-03-2018 IPR001543 Surface presentation of antigen (SpoA) CIG75_RS12000 98b2a7748c458411c9fdf9f0784e7e57 441 Gene3D G3DSA:3.40.1550.10 3 81 3.3E-19 T 28-03-2018 IPR028976 CheC-like domain CIG75_RS19305 f4bb267a44b97b7ddf998979f971255e 665 Pfam PF02780 Transketolase, C-terminal domain 551 657 2.2E-9 T 28-03-2018 IPR033248 Transketolase, C-terminal domain CIG75_RS19305 f4bb267a44b97b7ddf998979f971255e 665 SUPERFAMILY SSF52518 4 331 2.58E-116 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CIG75_RS19305 f4bb267a44b97b7ddf998979f971255e 665 ProSitePatterns PS00802 Transketolase signature 2. 467 483 - T 28-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CIG75_RS19305 f4bb267a44b97b7ddf998979f971255e 665 SUPERFAMILY SSF52922 535 665 3.01E-42 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CIG75_RS19305 f4bb267a44b97b7ddf998979f971255e 665 ProSitePatterns PS00801 Transketolase signature 1. 14 34 - T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CIG75_RS19305 f4bb267a44b97b7ddf998979f971255e 665 Pfam PF02779 Transketolase, pyrimidine binding domain 353 524 3.4E-44 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CIG75_RS19305 f4bb267a44b97b7ddf998979f971255e 665 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 6 337 1.1E-153 T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CIG75_RS19305 f4bb267a44b97b7ddf998979f971255e 665 SMART SM00861 354 525 2.3E-67 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CIG75_RS19305 f4bb267a44b97b7ddf998979f971255e 665 Gene3D G3DSA:3.40.50.970 364 541 3.0E-42 T 28-03-2018 CIG75_RS19305 f4bb267a44b97b7ddf998979f971255e 665 Gene3D G3DSA:3.40.50.920 542 664 4.0E-32 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CIG75_RS19305 f4bb267a44b97b7ddf998979f971255e 665 Gene3D G3DSA:3.40.50.970 1 363 5.1E-111 T 28-03-2018 CIG75_RS19305 f4bb267a44b97b7ddf998979f971255e 665 TIGRFAM TIGR00232 tktlase_bact: transketolase 9 664 5.5E-287 T 28-03-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 CIG75_RS19305 f4bb267a44b97b7ddf998979f971255e 665 SUPERFAMILY SSF52518 336 526 7.79E-68 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CIG75_RS07815 97f6d7f50060941de6612f74e84ee11d 182 Gene3D G3DSA:3.60.21.10 1 170 5.9E-18 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CIG75_RS07815 97f6d7f50060941de6612f74e84ee11d 182 SUPERFAMILY SSF56300 6 152 1.01E-33 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CIG75_RS07815 97f6d7f50060941de6612f74e84ee11d 182 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 6 149 2.5E-24 T 28-03-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 CIG75_RS07815 97f6d7f50060941de6612f74e84ee11d 182 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 6 152 1.0E-24 T 28-03-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 CIG75_RS19715 95ac70d8a2a0683e3cc87b8578634bb4 92 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 28-03-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CIG75_RS19715 95ac70d8a2a0683e3cc87b8578634bb4 92 Gene3D G3DSA:3.30.860.10 1 92 1.1E-40 T 28-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CIG75_RS19715 95ac70d8a2a0683e3cc87b8578634bb4 92 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 3.5E-24 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CIG75_RS19715 95ac70d8a2a0683e3cc87b8578634bb4 92 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 3.5E-24 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CIG75_RS19715 95ac70d8a2a0683e3cc87b8578634bb4 92 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 3.5E-24 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CIG75_RS19715 95ac70d8a2a0683e3cc87b8578634bb4 92 PIRSF PIRSF002144 1 92 4.4E-32 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CIG75_RS19715 95ac70d8a2a0683e3cc87b8578634bb4 92 SUPERFAMILY SSF54570 3 84 3.4E-36 T 28-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CIG75_RS19715 95ac70d8a2a0683e3cc87b8578634bb4 92 Pfam PF00203 Ribosomal protein S19 3 83 2.6E-37 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CIG75_RS19715 95ac70d8a2a0683e3cc87b8578634bb4 92 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.636 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CIG75_RS19715 95ac70d8a2a0683e3cc87b8578634bb4 92 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 92 6.1E-47 T 28-03-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 CIG75_RS16150 9af2455025afdfe8b51d3a702ee16413 392 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 390 2.2E-148 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CIG75_RS16150 9af2455025afdfe8b51d3a702ee16413 392 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 87 105 - T 28-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 CIG75_RS16150 9af2455025afdfe8b51d3a702ee16413 392 PIRSF PIRSF000429 1 392 3.7E-136 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CIG75_RS16150 9af2455025afdfe8b51d3a702ee16413 392 ProSitePatterns PS00099 Thiolases active site. 373 386 - T 28-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 CIG75_RS16150 9af2455025afdfe8b51d3a702ee16413 392 SUPERFAMILY SSF53901 270 391 8.91E-47 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS16150 9af2455025afdfe8b51d3a702ee16413 392 Gene3D G3DSA:3.40.47.10 1 134 5.6E-31 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS16150 9af2455025afdfe8b51d3a702ee16413 392 Gene3D G3DSA:3.40.47.10 145 264 4.8E-26 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS16150 9af2455025afdfe8b51d3a702ee16413 392 Pfam PF00108 Thiolase, N-terminal domain 5 261 6.0E-77 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CIG75_RS16150 9af2455025afdfe8b51d3a702ee16413 392 SUPERFAMILY SSF53901 1 266 8.57E-81 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS16150 9af2455025afdfe8b51d3a702ee16413 392 Gene3D G3DSA:3.40.47.10 265 389 3.7E-37 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS16150 9af2455025afdfe8b51d3a702ee16413 392 ProSitePatterns PS00737 Thiolases signature 2. 338 354 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CIG75_RS16150 9af2455025afdfe8b51d3a702ee16413 392 Pfam PF02803 Thiolase, C-terminal domain 270 390 7.5E-52 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CIG75_RS08620 9973bb28b7a66e87dc1867bf6bd8d102 730 Gene3D G3DSA:1.20.1110.10 181 439 3.0E-48 T 28-03-2018 CIG75_RS08620 9973bb28b7a66e87dc1867bf6bd8d102 730 Gene3D G3DSA:3.40.50.1000 547 687 3.1E-44 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS08620 9973bb28b7a66e87dc1867bf6bd8d102 730 SUPERFAMILY SSF81665 670 699 2.35E-15 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CIG75_RS08620 9973bb28b7a66e87dc1867bf6bd8d102 730 SUPERFAMILY SSF81665 161 220 2.35E-15 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CIG75_RS08620 9973bb28b7a66e87dc1867bf6bd8d102 730 SUPERFAMILY SSF81665 317 415 2.35E-15 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CIG75_RS08620 9973bb28b7a66e87dc1867bf6bd8d102 730 PRINTS PR00942 Copper-transporting ATPase 1 signature 60 80 1.4E-7 T 28-03-2018 CIG75_RS08620 9973bb28b7a66e87dc1867bf6bd8d102 730 PRINTS PR00942 Copper-transporting ATPase 1 signature 31 54 1.4E-7 T 28-03-2018 CIG75_RS08620 9973bb28b7a66e87dc1867bf6bd8d102 730 PRINTS PR00942 Copper-transporting ATPase 1 signature 5 30 1.4E-7 T 28-03-2018 CIG75_RS08620 9973bb28b7a66e87dc1867bf6bd8d102 730 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 189 702 2.0E-94 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CIG75_RS08620 9973bb28b7a66e87dc1867bf6bd8d102 730 Pfam PF00702 haloacid dehalogenase-like hydrolase 418 635 4.4E-43 T 28-03-2018 CIG75_RS08620 9973bb28b7a66e87dc1867bf6bd8d102 730 Gene3D G3DSA:3.30.70.100 1 75 5.4E-23 T 28-03-2018 CIG75_RS08620 9973bb28b7a66e87dc1867bf6bd8d102 730 ProSitePatterns PS01047 Heavy-metal-associated domain. 10 39 - T 28-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 CIG75_RS08620 9973bb28b7a66e87dc1867bf6bd8d102 730 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 155 723 3.0E-201 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CIG75_RS08620 9973bb28b7a66e87dc1867bf6bd8d102 730 Pfam PF00122 E1-E2 ATPase 217 400 2.3E-57 T 28-03-2018 CIG75_RS08620 9973bb28b7a66e87dc1867bf6bd8d102 730 Gene3D G3DSA:3.40.1110.10 440 546 5.4E-32 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CIG75_RS08620 9973bb28b7a66e87dc1867bf6bd8d102 730 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 266 280 1.2E-29 T 28-03-2018 CIG75_RS08620 9973bb28b7a66e87dc1867bf6bd8d102 730 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 621 640 1.2E-29 T 28-03-2018 CIG75_RS08620 9973bb28b7a66e87dc1867bf6bd8d102 730 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 644 656 1.2E-29 T 28-03-2018 CIG75_RS08620 9973bb28b7a66e87dc1867bf6bd8d102 730 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 568 578 1.2E-29 T 28-03-2018 CIG75_RS08620 9973bb28b7a66e87dc1867bf6bd8d102 730 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 421 435 1.2E-29 T 28-03-2018 CIG75_RS08620 9973bb28b7a66e87dc1867bf6bd8d102 730 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 546 557 1.2E-29 T 28-03-2018 CIG75_RS08620 9973bb28b7a66e87dc1867bf6bd8d102 730 SUPERFAMILY SSF81653 220 316 1.57E-29 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CIG75_RS08620 9973bb28b7a66e87dc1867bf6bd8d102 730 SUPERFAMILY SSF55008 4 71 3.8E-20 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CIG75_RS08620 9973bb28b7a66e87dc1867bf6bd8d102 730 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 423 429 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CIG75_RS08620 9973bb28b7a66e87dc1867bf6bd8d102 730 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 136 724 7.5E-190 T 28-03-2018 CIG75_RS08620 9973bb28b7a66e87dc1867bf6bd8d102 730 SUPERFAMILY SSF56784 419 439 1.21E-64 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS08620 9973bb28b7a66e87dc1867bf6bd8d102 730 SUPERFAMILY SSF56784 479 721 1.21E-64 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS08620 9973bb28b7a66e87dc1867bf6bd8d102 730 PRINTS PR00943 Copper-transporting ATPase signature 339 353 5.0E-16 T 28-03-2018 CIG75_RS08620 9973bb28b7a66e87dc1867bf6bd8d102 730 PRINTS PR00943 Copper-transporting ATPase signature 598 615 5.0E-16 T 28-03-2018 CIG75_RS08620 9973bb28b7a66e87dc1867bf6bd8d102 730 PRINTS PR00943 Copper-transporting ATPase signature 49 69 5.0E-16 T 28-03-2018 CIG75_RS08620 9973bb28b7a66e87dc1867bf6bd8d102 730 PRINTS PR00943 Copper-transporting ATPase signature 404 419 5.0E-16 T 28-03-2018 CIG75_RS08620 9973bb28b7a66e87dc1867bf6bd8d102 730 PRINTS PR00943 Copper-transporting ATPase signature 140 159 5.0E-16 T 28-03-2018 CIG75_RS08620 9973bb28b7a66e87dc1867bf6bd8d102 730 PRINTS PR00943 Copper-transporting ATPase signature 206 224 5.0E-16 T 28-03-2018 CIG75_RS08620 9973bb28b7a66e87dc1867bf6bd8d102 730 Pfam PF00403 Heavy-metal-associated domain 7 67 4.9E-15 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CIG75_RS08690 580368762c4219d2c09c9911cdb7682a 431 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 1.5E-25 T 28-03-2018 CIG75_RS08690 580368762c4219d2c09c9911cdb7682a 431 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 237 253 1.5E-25 T 28-03-2018 CIG75_RS08690 580368762c4219d2c09c9911cdb7682a 431 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 264 286 1.5E-25 T 28-03-2018 CIG75_RS08690 580368762c4219d2c09c9911cdb7682a 431 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 153 171 1.5E-25 T 28-03-2018 CIG75_RS08690 580368762c4219d2c09c9911cdb7682a 431 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 106 124 1.5E-25 T 28-03-2018 CIG75_RS08690 580368762c4219d2c09c9911cdb7682a 431 SUPERFAMILY SSF55424 325 430 3.95E-23 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CIG75_RS08690 580368762c4219d2c09c9911cdb7682a 431 Gene3D G3DSA:3.50.50.60 106 246 2.5E-33 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS08690 580368762c4219d2c09c9911cdb7682a 431 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 309 2.1E-62 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS08690 580368762c4219d2c09c9911cdb7682a 431 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 332 418 8.2E-6 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CIG75_RS08690 580368762c4219d2c09c9911cdb7682a 431 SUPERFAMILY SSF51905 4 316 8.84E-44 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS08690 580368762c4219d2c09c9911cdb7682a 431 Gene3D G3DSA:3.50.50.60 249 341 3.8E-8 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS08690 580368762c4219d2c09c9911cdb7682a 431 Gene3D G3DSA:3.30.390.30 342 431 1.2E-14 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CIG75_RS08690 580368762c4219d2c09c9911cdb7682a 431 Gene3D G3DSA:3.50.50.60 2 105 1.5E-11 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS08690 580368762c4219d2c09c9911cdb7682a 431 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 238 252 3.2E-19 T 28-03-2018 CIG75_RS08690 580368762c4219d2c09c9911cdb7682a 431 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 279 286 3.2E-19 T 28-03-2018 CIG75_RS08690 580368762c4219d2c09c9911cdb7682a 431 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 3.2E-19 T 28-03-2018 CIG75_RS08690 580368762c4219d2c09c9911cdb7682a 431 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 153 178 3.2E-19 T 28-03-2018 CIG75_RS18390 7c4a96d5bd67e2fa99d0266e01b12d18 157 Pfam PF03862 SpoVAC/SpoVAEB sporulation membrane protein 33 149 4.7E-40 T 28-03-2018 IPR005562 SpoVA CIG75_RS18390 7c4a96d5bd67e2fa99d0266e01b12d18 157 TIGRFAM TIGR02838 spore_V_AC: stage V sporulation protein AC 14 153 1.9E-59 T 28-03-2018 IPR014203 Sporulation stage V, protein AC CIG75_RS15765 ad97576bfb43eb2bbc43dd9a9c1d92aa 180 Pfam PF03079 ARD/ARD' family 41 169 2.5E-35 T 28-03-2018 IPR004313 Acireductone dioxygenase ARD family GO:0010309|GO:0055114 KEGG: 00270+1.13.11.54|MetaCyc: PWY-4361|Reactome: R-HSA-1237112 CIG75_RS15765 ad97576bfb43eb2bbc43dd9a9c1d92aa 180 Hamap MF_01682 Acireductone dioxygenase [mtnD]. 1 176 29.835 T 28-03-2018 IPR023956 Acireductone dioxygenase ARD, bacteria GO:0005506|GO:0010308|GO:0010309|GO:0016151|GO:0019284|GO:0055114 KEGG: 00270+1.13.11.53+1.13.11.54|MetaCyc: PWY-4361|MetaCyc: PWY-5389 CIG75_RS15765 ad97576bfb43eb2bbc43dd9a9c1d92aa 180 SUPERFAMILY SSF51182 14 176 4.46E-30 T 28-03-2018 IPR011051 RmlC-like cupin domain CIG75_RS15765 ad97576bfb43eb2bbc43dd9a9c1d92aa 180 Gene3D G3DSA:2.60.120.10 2 161 5.8E-35 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CIG75_RS03345 13c8de434c8696be64f9558f8f75fd74 483 Gene3D G3DSA:3.90.970.10 418 482 1.7E-31 T 28-03-2018 IPR014714 Glutamate mutase E subunit, C-terminal domain GO:0016866|GO:0019670|GO:0031419 KEGG: 00630+5.4.99.1|KEGG: 00660+5.4.99.1|MetaCyc: PWY-5087|MetaCyc: PWY-5103|MetaCyc: PWY-6728 CIG75_RS03345 13c8de434c8696be64f9558f8f75fd74 483 SUPERFAMILY SSF51703 1 482 2.67E-197 T 28-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CIG75_RS03345 13c8de434c8696be64f9558f8f75fd74 483 Gene3D G3DSA:3.20.20.240 1 417 4.4E-110 T 28-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CIG75_RS03345 13c8de434c8696be64f9558f8f75fd74 483 PIRSF PIRSF001495 1 483 1.9E-218 T 28-03-2018 IPR006396 Glutamate mutase epsilon subunit GO:0019670|GO:0050097 KEGG: 00630+5.4.99.1|KEGG: 00660+5.4.99.1|MetaCyc: PWY-5087|MetaCyc: PWY-5103|MetaCyc: PWY-6728 CIG75_RS03345 13c8de434c8696be64f9558f8f75fd74 483 Hamap MF_01923 Glutamate mutase epsilon subunit [glmE]. 2 482 52.345 T 28-03-2018 IPR006396 Glutamate mutase epsilon subunit GO:0019670|GO:0050097 KEGG: 00630+5.4.99.1|KEGG: 00660+5.4.99.1|MetaCyc: PWY-5087|MetaCyc: PWY-5103|MetaCyc: PWY-6728 CIG75_RS03345 13c8de434c8696be64f9558f8f75fd74 483 TIGRFAM TIGR01503 MthylAspMut_E: methylaspartate mutase, E subunit 3 482 1.4E-227 T 28-03-2018 IPR006396 Glutamate mutase epsilon subunit GO:0019670|GO:0050097 KEGG: 00630+5.4.99.1|KEGG: 00660+5.4.99.1|MetaCyc: PWY-5087|MetaCyc: PWY-5103|MetaCyc: PWY-6728 CIG75_RS03345 13c8de434c8696be64f9558f8f75fd74 483 Pfam PF06368 Methylaspartate mutase E chain (MutE) 44 482 1.2E-215 T 28-03-2018 IPR006396 Glutamate mutase epsilon subunit GO:0019670|GO:0050097 KEGG: 00630+5.4.99.1|KEGG: 00660+5.4.99.1|MetaCyc: PWY-5087|MetaCyc: PWY-5103|MetaCyc: PWY-6728 CIG75_RS00190 32ed6a68d87a9af07b3d6547f3141873 842 SUPERFAMILY SSF56719 29 485 2.35E-185 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CIG75_RS00190 32ed6a68d87a9af07b3d6547f3141873 842 Gene3D G3DSA:1.10.268.10 343 485 7.9E-56 T 28-03-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CIG75_RS00190 32ed6a68d87a9af07b3d6547f3141873 842 Gene3D G3DSA:3.90.199.10 33 213 4.6E-87 T 28-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 CIG75_RS00190 32ed6a68d87a9af07b3d6547f3141873 842 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 10 827 0.0 T 28-03-2018 CIG75_RS00190 32ed6a68d87a9af07b3d6547f3141873 842 Gene3D G3DSA:2.120.10.90 495 829 7.4E-120 T 28-03-2018 CIG75_RS00190 32ed6a68d87a9af07b3d6547f3141873 842 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 5 829 24.916 T 28-03-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CIG75_RS00190 32ed6a68d87a9af07b3d6547f3141873 842 Gene3D G3DSA:3.30.1360.40 235 331 2.2E-39 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CIG75_RS00190 32ed6a68d87a9af07b3d6547f3141873 842 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 502 549 1.4E-13 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CIG75_RS00190 32ed6a68d87a9af07b3d6547f3141873 842 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 633 675 4.7E-9 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CIG75_RS00190 32ed6a68d87a9af07b3d6547f3141873 842 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 553 601 3.8E-11 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CIG75_RS00190 32ed6a68d87a9af07b3d6547f3141873 842 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 780 827 3.7E-12 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CIG75_RS00190 32ed6a68d87a9af07b3d6547f3141873 842 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 731 776 3.7E-11 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CIG75_RS00190 32ed6a68d87a9af07b3d6547f3141873 842 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 680 726 8.6E-10 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CIG75_RS00190 32ed6a68d87a9af07b3d6547f3141873 842 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 31 469 2.0E-165 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CIG75_RS00190 32ed6a68d87a9af07b3d6547f3141873 842 SMART SM00434 10 463 2.6E-293 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CIG75_RS00190 32ed6a68d87a9af07b3d6547f3141873 842 SUPERFAMILY SSF101904 497 834 1.11E-102 T 28-03-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal CIG75_RS17605 c34253d77580541610131eb3fda718d8 1099 Gene3D G3DSA:3.40.50.1380 950 1075 2.5E-26 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CIG75_RS17605 c34253d77580541610131eb3fda718d8 1099 SUPERFAMILY SSF48108 401 546 4.05E-44 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CIG75_RS17605 c34253d77580541610131eb3fda718d8 1099 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 26 40 1.9E-66 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CIG75_RS17605 c34253d77580541610131eb3fda718d8 1099 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 55 65 1.9E-66 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CIG75_RS17605 c34253d77580541610131eb3fda718d8 1099 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 175 187 1.9E-66 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CIG75_RS17605 c34253d77580541610131eb3fda718d8 1099 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 211 230 1.9E-66 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CIG75_RS17605 c34253d77580541610131eb3fda718d8 1099 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 303 332 1.9E-66 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CIG75_RS17605 c34253d77580541610131eb3fda718d8 1099 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 385 403 1.9E-66 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CIG75_RS17605 c34253d77580541610131eb3fda718d8 1099 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 246 263 1.9E-66 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CIG75_RS17605 c34253d77580541610131eb3fda718d8 1099 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 13 1071 0.0 T 28-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CIG75_RS17605 c34253d77580541610131eb3fda718d8 1099 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 8 1083 12.644 T 28-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CIG75_RS17605 c34253d77580541610131eb3fda718d8 1099 SMART SM00851 978 1062 3.2E-11 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CIG75_RS17605 c34253d77580541610131eb3fda718d8 1099 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 859 866 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CIG75_RS17605 c34253d77580541610131eb3fda718d8 1099 Gene3D G3DSA:1.10.1030.10 411 530 1.6E-42 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CIG75_RS17605 c34253d77580541610131eb3fda718d8 1099 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 303 310 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CIG75_RS17605 c34253d77580541610131eb3fda718d8 1099 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 135 340 1.3E-78 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CIG75_RS17605 c34253d77580541610131eb3fda718d8 1099 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 666 740 2.2E-14 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CIG75_RS17605 c34253d77580541610131eb3fda718d8 1099 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 761 894 2.6E-19 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CIG75_RS17605 c34253d77580541610131eb3fda718d8 1099 SMART SM01096 419 539 3.7E-51 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CIG75_RS17605 c34253d77580541610131eb3fda718d8 1099 SUPERFAMILY SSF56059 764 956 3.01E-89 T 28-03-2018 CIG75_RS17605 c34253d77580541610131eb3fda718d8 1099 SUPERFAMILY SSF56059 666 734 3.01E-89 T 28-03-2018 CIG75_RS17605 c34253d77580541610131eb3fda718d8 1099 Gene3D G3DSA:3.40.50.20 11 120 8.3E-37 T 28-03-2018 CIG75_RS17605 c34253d77580541610131eb3fda718d8 1099 SUPERFAMILY SSF52440 549 668 1.09E-44 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CIG75_RS17605 c34253d77580541610131eb3fda718d8 1099 SUPERFAMILY SSF52440 12 134 8.63E-47 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CIG75_RS17605 c34253d77580541610131eb3fda718d8 1099 SUPERFAMILY SSF52335 958 1082 4.45E-22 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CIG75_RS17605 c34253d77580541610131eb3fda718d8 1099 Gene3D G3DSA:3.30.470.20 756 949 3.2E-36 T 28-03-2018 CIG75_RS17605 c34253d77580541610131eb3fda718d8 1099 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 702 716 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CIG75_RS17605 c34253d77580541610131eb3fda718d8 1099 Pfam PF02142 MGS-like domain 979 1062 8.7E-11 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CIG75_RS17605 c34253d77580541610131eb3fda718d8 1099 SUPERFAMILY SSF56059 135 406 4.24E-108 T 28-03-2018 CIG75_RS17605 c34253d77580541610131eb3fda718d8 1099 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 12 1091 13.177 T 28-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CIG75_RS17605 c34253d77580541610131eb3fda718d8 1099 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 422 539 5.9E-37 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CIG75_RS17605 c34253d77580541610131eb3fda718d8 1099 SMART SM01209 665 862 0.0063 T 28-03-2018 CIG75_RS17605 c34253d77580541610131eb3fda718d8 1099 Gene3D G3DSA:3.40.50.20 531 647 7.4E-54 T 28-03-2018 CIG75_RS17605 c34253d77580541610131eb3fda718d8 1099 Gene3D G3DSA:3.30.1490.20 648 744 3.9E-19 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CIG75_RS17605 c34253d77580541610131eb3fda718d8 1099 Gene3D G3DSA:3.30.470.20 127 408 2.6E-63 T 28-03-2018 CIG75_RS13720 95c2597ea3535926e68c4e16ed9c0382 549 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 86 468 1.8E-79 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CIG75_RS13720 95c2597ea3535926e68c4e16ed9c0382 549 PIRSF PIRSF002741 3 548 1.2E-108 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CIG75_RS13720 95c2597ea3535926e68c4e16ed9c0382 549 Gene3D G3DSA:3.10.105.10 310 517 4.0E-50 T 28-03-2018 CIG75_RS13720 95c2597ea3535926e68c4e16ed9c0382 549 Gene3D G3DSA:3.40.190.10 176 309 4.0E-32 T 28-03-2018 CIG75_RS13720 95c2597ea3535926e68c4e16ed9c0382 549 Gene3D G3DSA:3.90.76.10 66 175 9.2E-30 T 28-03-2018 CIG75_RS13720 95c2597ea3535926e68c4e16ed9c0382 549 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 90 112 - T 28-03-2018 IPR023765 Solute-binding protein family 5, conserved site CIG75_RS13720 95c2597ea3535926e68c4e16ed9c0382 549 SUPERFAMILY SSF53850 39 544 1.01E-125 T 28-03-2018 CIG75_RS19750 7853d794bfc8cdd28a0cbe9a1e8fdd24 691 Pfam PF00679 Elongation factor G C-terminus 597 683 8.7E-31 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CIG75_RS19750 7853d794bfc8cdd28a0cbe9a1e8fdd24 691 Gene3D G3DSA:3.30.230.10 489 610 7.3E-45 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CIG75_RS19750 7853d794bfc8cdd28a0cbe9a1e8fdd24 691 Hamap MF_00054_B Elongation factor G [fusA]. 6 688 112.761 T 28-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CIG75_RS19750 7853d794bfc8cdd28a0cbe9a1e8fdd24 691 SUPERFAMILY SSF54980 399 477 1.65E-24 T 28-03-2018 IPR035647 EF-G domain III/V-like CIG75_RS19750 7853d794bfc8cdd28a0cbe9a1e8fdd24 691 SMART SM00838 597 684 3.3E-56 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CIG75_RS19750 7853d794bfc8cdd28a0cbe9a1e8fdd24 691 Pfam PF14492 Elongation Factor G, domain II 401 475 9.6E-34 T 28-03-2018 CIG75_RS19750 7853d794bfc8cdd28a0cbe9a1e8fdd24 691 Gene3D G3DSA:2.40.30.10 273 392 3.7E-30 T 28-03-2018 CIG75_RS19750 7853d794bfc8cdd28a0cbe9a1e8fdd24 691 SUPERFAMILY SSF50447 263 401 3.28E-36 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CIG75_RS19750 7853d794bfc8cdd28a0cbe9a1e8fdd24 691 SUPERFAMILY SSF54211 476 596 6.07E-46 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CIG75_RS19750 7853d794bfc8cdd28a0cbe9a1e8fdd24 691 SMART SM00889 477 595 8.1E-74 T 28-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CIG75_RS19750 7853d794bfc8cdd28a0cbe9a1e8fdd24 691 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site CIG75_RS19750 7853d794bfc8cdd28a0cbe9a1e8fdd24 691 Gene3D G3DSA:3.30.70.870 394 488 5.9E-35 T 28-03-2018 CIG75_RS19750 7853d794bfc8cdd28a0cbe9a1e8fdd24 691 Gene3D G3DSA:3.40.50.300 1 272 1.3E-59 T 28-03-2018 CIG75_RS19750 7853d794bfc8cdd28a0cbe9a1e8fdd24 691 TIGRFAM TIGR00484 EF-G: translation elongation factor G 1 689 0.0 T 28-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CIG75_RS19750 7853d794bfc8cdd28a0cbe9a1e8fdd24 691 PRINTS PR00315 GTP-binding elongation factor signature 78 88 1.5E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CIG75_RS19750 7853d794bfc8cdd28a0cbe9a1e8fdd24 691 PRINTS PR00315 GTP-binding elongation factor signature 94 105 1.5E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CIG75_RS19750 7853d794bfc8cdd28a0cbe9a1e8fdd24 691 PRINTS PR00315 GTP-binding elongation factor signature 130 139 1.5E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CIG75_RS19750 7853d794bfc8cdd28a0cbe9a1e8fdd24 691 PRINTS PR00315 GTP-binding elongation factor signature 12 25 1.5E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CIG75_RS19750 7853d794bfc8cdd28a0cbe9a1e8fdd24 691 PRINTS PR00315 GTP-binding elongation factor signature 58 66 1.5E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CIG75_RS19750 7853d794bfc8cdd28a0cbe9a1e8fdd24 691 Pfam PF00009 Elongation factor Tu GTP binding domain 9 279 1.0E-64 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CIG75_RS19750 7853d794bfc8cdd28a0cbe9a1e8fdd24 691 Pfam PF03144 Elongation factor Tu domain 2 321 388 4.6E-15 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CIG75_RS19750 7853d794bfc8cdd28a0cbe9a1e8fdd24 691 Pfam PF03764 Elongation factor G, domain IV 476 594 2.6E-47 T 28-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CIG75_RS19750 7853d794bfc8cdd28a0cbe9a1e8fdd24 691 SUPERFAMILY SSF52540 6 279 4.13E-109 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS19750 7853d794bfc8cdd28a0cbe9a1e8fdd24 691 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 179 5.2E-32 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CIG75_RS19750 7853d794bfc8cdd28a0cbe9a1e8fdd24 691 SUPERFAMILY SSF54980 597 687 1.01E-29 T 28-03-2018 IPR035647 EF-G domain III/V-like CIG75_RS19750 7853d794bfc8cdd28a0cbe9a1e8fdd24 691 Gene3D G3DSA:3.30.70.240 611 688 1.3E-30 T 28-03-2018 CIG75_RS06875 223f20b2f22a799c884d93d7bfff820f 249 Hamap MF_01974 Methionine aminopeptidase [map]. 2 249 41.179 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CIG75_RS06875 223f20b2f22a799c884d93d7bfff820f 249 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 2 247 1.1E-93 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CIG75_RS06875 223f20b2f22a799c884d93d7bfff820f 249 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 165 183 - T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CIG75_RS06875 223f20b2f22a799c884d93d7bfff820f 249 Gene3D G3DSA:3.90.230.10 1 248 4.3E-83 T 28-03-2018 CIG75_RS06875 223f20b2f22a799c884d93d7bfff820f 249 SUPERFAMILY SSF55920 2 247 2.36E-85 T 28-03-2018 IPR000994 Peptidase M24 CIG75_RS06875 223f20b2f22a799c884d93d7bfff820f 249 Pfam PF00557 Metallopeptidase family M24 13 240 2.0E-51 T 28-03-2018 IPR000994 Peptidase M24 CIG75_RS06875 223f20b2f22a799c884d93d7bfff820f 249 PRINTS PR00599 Methionine aminopeptidase-1 signature 67 80 1.1E-20 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CIG75_RS06875 223f20b2f22a799c884d93d7bfff820f 249 PRINTS PR00599 Methionine aminopeptidase-1 signature 159 171 1.1E-20 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CIG75_RS06875 223f20b2f22a799c884d93d7bfff820f 249 PRINTS PR00599 Methionine aminopeptidase-1 signature 190 202 1.1E-20 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CIG75_RS06875 223f20b2f22a799c884d93d7bfff820f 249 PRINTS PR00599 Methionine aminopeptidase-1 signature 89 105 1.1E-20 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CIG75_RS18500 7ed30c7aa6a83883003458451705c303 425 SUPERFAMILY SSF48179 196 287 1.56E-24 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CIG75_RS18500 7ed30c7aa6a83883003458451705c303 425 PIRSF PIRSF000124 2 418 4.3E-54 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CIG75_RS18500 7ed30c7aa6a83883003458451705c303 425 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 197 285 1.6E-23 T 28-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CIG75_RS18500 7ed30c7aa6a83883003458451705c303 425 Gene3D G3DSA:1.20.5.170 196 218 1.4E-10 T 28-03-2018 CIG75_RS18500 7ed30c7aa6a83883003458451705c303 425 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 3 409 3.3E-119 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CIG75_RS18500 7ed30c7aa6a83883003458451705c303 425 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3 173 1.7E-34 T 28-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CIG75_RS18500 7ed30c7aa6a83883003458451705c303 425 SUPERFAMILY SSF52413 303 413 1.19E-24 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CIG75_RS18500 7ed30c7aa6a83883003458451705c303 425 Gene3D G3DSA:3.40.50.720 219 422 1.6E-54 T 28-03-2018 CIG75_RS18500 7ed30c7aa6a83883003458451705c303 425 PIRSF PIRSF500136 1 425 1.6E-148 T 28-03-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 CIG75_RS18500 7ed30c7aa6a83883003458451705c303 425 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 312 413 7.9E-23 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CIG75_RS18500 7ed30c7aa6a83883003458451705c303 425 SUPERFAMILY SSF51735 2 187 4.74E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS18500 7ed30c7aa6a83883003458451705c303 425 Gene3D G3DSA:3.40.50.720 1 194 1.9E-39 T 28-03-2018 CIG75_RS18500 7ed30c7aa6a83883003458451705c303 425 SMART SM00984 312 413 3.8E-32 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CIG75_RS05260 9d587c11432fe9db173e72e750e2c316 224 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 43 177 1.3E-21 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CIG75_RS05260 9d587c11432fe9db173e72e750e2c316 224 SMART SM00478 47 194 2.2E-59 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CIG75_RS05260 9d587c11432fe9db173e72e750e2c316 224 Hamap MF_00942 Endonuclease III [nth]. 1 218 39.249 T 28-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 CIG75_RS05260 9d587c11432fe9db173e72e750e2c316 224 PIRSF PIRSF001435 12 221 2.4E-61 T 28-03-2018 CIG75_RS05260 9d587c11432fe9db173e72e750e2c316 224 Gene3D G3DSA:1.10.340.30 34 126 3.8E-28 T 28-03-2018 CIG75_RS05260 9d587c11432fe9db173e72e750e2c316 224 Pfam PF00633 Helix-hairpin-helix motif 109 136 3.6E-9 T 28-03-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 CIG75_RS05260 9d587c11432fe9db173e72e750e2c316 224 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 196 212 - T 28-03-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CIG75_RS05260 9d587c11432fe9db173e72e750e2c316 224 ProSitePatterns PS01155 Endonuclease III family signature. 111 140 - T 28-03-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 CIG75_RS05260 9d587c11432fe9db173e72e750e2c316 224 SUPERFAMILY SSF48150 16 215 1.73E-72 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CIG75_RS05260 9d587c11432fe9db173e72e750e2c316 224 Gene3D G3DSA:1.10.1670.10 127 224 1.8E-33 T 28-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CIG75_RS05260 9d587c11432fe9db173e72e750e2c316 224 TIGRFAM TIGR01083 nth: endonuclease III 15 203 5.3E-85 T 28-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 CIG75_RS10230 79828a2ff181dd0e1cfdd946ee4e98ff 321 SUPERFAMILY SSF161098 98 320 3.27E-68 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CIG75_RS10230 79828a2ff181dd0e1cfdd946ee4e98ff 321 SUPERFAMILY SSF161098 5 46 3.27E-68 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CIG75_RS10230 79828a2ff181dd0e1cfdd946ee4e98ff 321 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 137 314 1.1E-25 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CIG75_RS10230 79828a2ff181dd0e1cfdd946ee4e98ff 321 Gene3D G3DSA:1.10.3720.10 9 312 3.3E-42 T 28-03-2018 CIG75_RS15410 7c84c71d5cacb7b166703656ef9506b8 294 Pfam PF01476 LysM domain 81 123 2.9E-10 T 28-03-2018 IPR018392 LysM domain CIG75_RS15410 7c84c71d5cacb7b166703656ef9506b8 294 Pfam PF01476 LysM domain 37 77 1.0E-10 T 28-03-2018 IPR018392 LysM domain CIG75_RS15410 7c84c71d5cacb7b166703656ef9506b8 294 Gene3D G3DSA:3.10.350.10 35 80 2.7E-11 T 28-03-2018 CIG75_RS15410 7c84c71d5cacb7b166703656ef9506b8 294 SUPERFAMILY SSF54106 37 77 3.4E-8 T 28-03-2018 IPR018392 LysM domain CIG75_RS15410 7c84c71d5cacb7b166703656ef9506b8 294 SMART SM00257 35 78 5.5E-10 T 28-03-2018 IPR018392 LysM domain CIG75_RS15410 7c84c71d5cacb7b166703656ef9506b8 294 SMART SM00257 80 123 5.3E-9 T 28-03-2018 IPR018392 LysM domain CIG75_RS15410 7c84c71d5cacb7b166703656ef9506b8 294 Pfam PF06725 3D domain 224 293 1.6E-16 T 28-03-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 CIG75_RS15410 7c84c71d5cacb7b166703656ef9506b8 294 SUPERFAMILY SSF50685 225 273 3.38E-8 T 28-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CIG75_RS15410 7c84c71d5cacb7b166703656ef9506b8 294 Gene3D G3DSA:2.40.40.10 81 292 8.4E-29 T 28-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CIG75_RS15410 7c84c71d5cacb7b166703656ef9506b8 294 SUPERFAMILY SSF54106 80 123 4.97E-9 T 28-03-2018 IPR018392 LysM domain CIG75_RS01565 1f61f65b97d5db5eaa2423c64caca7f3 168 Pfam PF04892 VanZ like family 3 144 9.9E-25 T 28-03-2018 IPR006976 VanZ-like CIG75_RS08025 cd84cba78a18d36544135aa85a3826e2 432 Gene3D G3DSA:3.90.190.20 297 431 4.2E-27 T 28-03-2018 CIG75_RS08025 cd84cba78a18d36544135aa85a3826e2 432 PIRSF PIRSF001563 1 432 2.5E-142 T 28-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 CIG75_RS08025 cd84cba78a18d36544135aa85a3826e2 432 Gene3D G3DSA:3.40.1190.10 2 296 5.2E-81 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CIG75_RS08025 cd84cba78a18d36544135aa85a3826e2 432 Pfam PF08245 Mur ligase middle domain 45 271 9.6E-14 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CIG75_RS08025 cd84cba78a18d36544135aa85a3826e2 432 SUPERFAMILY SSF53244 297 430 4.58E-26 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CIG75_RS08025 cd84cba78a18d36544135aa85a3826e2 432 SUPERFAMILY SSF53623 4 295 2.88E-89 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CIG75_RS08025 cd84cba78a18d36544135aa85a3826e2 432 Pfam PF02875 Mur ligase family, glutamate ligase domain 295 347 4.1E-9 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CIG75_RS08025 cd84cba78a18d36544135aa85a3826e2 432 TIGRFAM TIGR01499 folC: bifunctional protein FolC 23 429 1.0E-114 T 28-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 CIG75_RS07900 5c928de8c72966792e3cf5e1a6bcbb66 308 PRINTS PR00151 Porphobilinogen deaminase signature 141 158 4.0E-47 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CIG75_RS07900 5c928de8c72966792e3cf5e1a6bcbb66 308 PRINTS PR00151 Porphobilinogen deaminase signature 228 245 4.0E-47 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CIG75_RS07900 5c928de8c72966792e3cf5e1a6bcbb66 308 PRINTS PR00151 Porphobilinogen deaminase signature 43 63 4.0E-47 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CIG75_RS07900 5c928de8c72966792e3cf5e1a6bcbb66 308 PRINTS PR00151 Porphobilinogen deaminase signature 74 93 4.0E-47 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CIG75_RS07900 5c928de8c72966792e3cf5e1a6bcbb66 308 PRINTS PR00151 Porphobilinogen deaminase signature 122 139 4.0E-47 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CIG75_RS07900 5c928de8c72966792e3cf5e1a6bcbb66 308 Gene3D G3DSA:3.30.160.40 219 302 3.1E-23 T 28-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CIG75_RS07900 5c928de8c72966792e3cf5e1a6bcbb66 308 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 4 293 5.4E-110 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CIG75_RS07900 5c928de8c72966792e3cf5e1a6bcbb66 308 PIRSF PIRSF001438 1 308 4.2E-121 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CIG75_RS07900 5c928de8c72966792e3cf5e1a6bcbb66 308 Gene3D G3DSA:3.40.190.10 105 197 6.0E-38 T 28-03-2018 CIG75_RS07900 5c928de8c72966792e3cf5e1a6bcbb66 308 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 229 245 - T 28-03-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CIG75_RS07900 5c928de8c72966792e3cf5e1a6bcbb66 308 SUPERFAMILY SSF53850 2 216 3.8E-80 T 28-03-2018 CIG75_RS07900 5c928de8c72966792e3cf5e1a6bcbb66 308 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 3 293 39.278 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CIG75_RS07900 5c928de8c72966792e3cf5e1a6bcbb66 308 SUPERFAMILY SSF54782 218 306 3.66E-24 T 28-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CIG75_RS07900 5c928de8c72966792e3cf5e1a6bcbb66 308 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 225 291 3.0E-19 T 28-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CIG75_RS07900 5c928de8c72966792e3cf5e1a6bcbb66 308 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 4 211 1.5E-80 T 28-03-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CIG75_RS07900 5c928de8c72966792e3cf5e1a6bcbb66 308 Gene3D G3DSA:3.40.190.10 1 104 6.0E-44 T 28-03-2018 CIG75_RS00905 d7cb8c1cefc0f3db41794f55e58baa7d 1189 Gene3D G3DSA:3.40.50.300 459 618 1.2E-9 T 28-03-2018 CIG75_RS00905 d7cb8c1cefc0f3db41794f55e58baa7d 1189 SUPERFAMILY SSF52540 469 741 3.01E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS00905 d7cb8c1cefc0f3db41794f55e58baa7d 1189 SUPERFAMILY SSF52467 21 226 7.09E-8 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CIG75_RS00905 d7cb8c1cefc0f3db41794f55e58baa7d 1189 Pfam PF13289 SIR2-like domain 121 240 1.5E-20 T 28-03-2018 CIG75_RS00905 d7cb8c1cefc0f3db41794f55e58baa7d 1189 SMART SM00382 498 641 0.0046 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS00905 d7cb8c1cefc0f3db41794f55e58baa7d 1189 Pfam PF00931 NB-ARC domain 498 757 3.6E-6 T 28-03-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207 CIG75_RS02610 525cfd300a447c478eede4641a3ed40c 442 SUPERFAMILY SSF55205 8 428 1.64E-92 T 28-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CIG75_RS02610 525cfd300a447c478eede4641a3ed40c 442 Gene3D G3DSA:3.65.10.10 26 224 5.8E-36 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CIG75_RS02610 525cfd300a447c478eede4641a3ed40c 442 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 12 418 3.2E-62 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CIG75_RS02610 525cfd300a447c478eede4641a3ed40c 442 Gene3D G3DSA:3.65.10.10 225 431 1.3E-31 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CIG75_RS17790 0427acd42b9b68224d0c594aa8c97ff1 368 Pfam PF00990 Diguanylate cyclase, GGDEF domain 207 363 1.6E-47 T 28-03-2018 IPR000160 GGDEF domain CIG75_RS17790 0427acd42b9b68224d0c594aa8c97ff1 368 SUPERFAMILY SSF55073 212 365 6.02E-46 T 28-03-2018 IPR029787 Nucleotide cyclase CIG75_RS17790 0427acd42b9b68224d0c594aa8c97ff1 368 Gene3D G3DSA:3.30.70.270 190 367 1.2E-53 T 28-03-2018 CIG75_RS17790 0427acd42b9b68224d0c594aa8c97ff1 368 SMART SM00267 196 367 1.7E-52 T 28-03-2018 IPR000160 GGDEF domain CIG75_RS17790 0427acd42b9b68224d0c594aa8c97ff1 368 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 204 365 3.4E-51 T 28-03-2018 IPR000160 GGDEF domain CIG75_RS14930 c5934bdf00cec9c0e931f267174f079e 271 SUPERFAMILY SSF82771 170 234 6.67E-7 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CIG75_RS14930 c5934bdf00cec9c0e931f267174f079e 271 Gene3D G3DSA:1.10.10.10 14 132 0.0015 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS14930 c5934bdf00cec9c0e931f267174f079e 271 Gene3D G3DSA:3.40.1440.10 168 271 3.6E-11 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CIG75_RS10630 e0202bad4ecced86fbf349915324690f 1991 Gene3D G3DSA:3.30.559.10 30 249 2.1E-49 T 28-03-2018 CIG75_RS10630 e0202bad4ecced86fbf349915324690f 1991 SUPERFAMILY SSF52777 1549 1727 1.56E-29 T 28-03-2018 CIG75_RS10630 e0202bad4ecced86fbf349915324690f 1991 Gene3D G3DSA:1.10.1200.10 1425 1523 3.2E-19 T 28-03-2018 CIG75_RS10630 e0202bad4ecced86fbf349915324690f 1991 Pfam PF00668 Condensation domain 44 491 1.8E-114 T 28-03-2018 IPR001242 Condensation domain CIG75_RS10630 e0202bad4ecced86fbf349915324690f 1991 Pfam PF00668 Condensation domain 1544 1985 5.7E-61 T 28-03-2018 IPR001242 Condensation domain CIG75_RS10630 e0202bad4ecced86fbf349915324690f 1991 Gene3D G3DSA:3.40.50.150 1025 1322 5.8E-20 T 28-03-2018 CIG75_RS10630 e0202bad4ecced86fbf349915324690f 1991 Gene3D G3DSA:3.40.50.980 659 818 1.6E-41 T 28-03-2018 CIG75_RS10630 e0202bad4ecced86fbf349915324690f 1991 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1464 1479 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS10630 e0202bad4ecced86fbf349915324690f 1991 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 532 934 9.3E-150 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS10630 e0202bad4ecced86fbf349915324690f 1991 Gene3D G3DSA:3.30.559.10 1536 1731 6.6E-24 T 28-03-2018 CIG75_RS10630 e0202bad4ecced86fbf349915324690f 1991 SUPERFAMILY SSF52777 1733 1983 1.67E-42 T 28-03-2018 CIG75_RS10630 e0202bad4ecced86fbf349915324690f 1991 SUPERFAMILY SSF52777 49 226 1.11E-46 T 28-03-2018 CIG75_RS10630 e0202bad4ecced86fbf349915324690f 1991 Pfam PF00550 Phosphopantetheine attachment site 1442 1502 1.9E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10630 e0202bad4ecced86fbf349915324690f 1991 Gene3D G3DSA:3.40.50.980 502 658 4.2E-52 T 28-03-2018 CIG75_RS10630 e0202bad4ecced86fbf349915324690f 1991 SUPERFAMILY SSF56801 1374 1453 2.75E-175 T 28-03-2018 CIG75_RS10630 e0202bad4ecced86fbf349915324690f 1991 SUPERFAMILY SSF56801 470 964 2.75E-175 T 28-03-2018 CIG75_RS10630 e0202bad4ecced86fbf349915324690f 1991 Pfam PF08241 Methyltransferase domain 1035 1134 4.4E-11 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CIG75_RS10630 e0202bad4ecced86fbf349915324690f 1991 SUPERFAMILY SSF53335 1013 1145 3.58E-23 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CIG75_RS10630 e0202bad4ecced86fbf349915324690f 1991 Gene3D G3DSA:3.30.300.30 1327 1421 1.1E-5 T 28-03-2018 CIG75_RS10630 e0202bad4ecced86fbf349915324690f 1991 Gene3D G3DSA:3.30.300.30 905 1024 1.9E-14 T 28-03-2018 CIG75_RS10630 e0202bad4ecced86fbf349915324690f 1991 SUPERFAMILY SSF52777 234 498 2.56E-68 T 28-03-2018 CIG75_RS10630 e0202bad4ecced86fbf349915324690f 1991 Gene3D G3DSA:2.30.38.10 819 900 1.9E-25 T 28-03-2018 CIG75_RS10630 e0202bad4ecced86fbf349915324690f 1991 Pfam PF00501 AMP-binding enzyme 511 910 2.9E-112 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS10630 e0202bad4ecced86fbf349915324690f 1991 SUPERFAMILY SSF47336 1432 1501 1.02E-16 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10630 e0202bad4ecced86fbf349915324690f 1991 ProSitePatterns PS00455 Putative AMP-binding domain signature. 653 664 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS12615 37fa63a2be467890ae3fec2c6112294b 449 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 382 392 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CIG75_RS12615 37fa63a2be467890ae3fec2c6112294b 449 Gene3D G3DSA:3.40.50.200 132 446 3.4E-97 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CIG75_RS12615 37fa63a2be467890ae3fec2c6112294b 449 PRINTS PR00723 Subtilisin serine protease family (S8) signature 226 239 1.3E-21 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CIG75_RS12615 37fa63a2be467890ae3fec2c6112294b 449 PRINTS PR00723 Subtilisin serine protease family (S8) signature 381 397 1.3E-21 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CIG75_RS12615 37fa63a2be467890ae3fec2c6112294b 449 PRINTS PR00723 Subtilisin serine protease family (S8) signature 188 207 1.3E-21 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CIG75_RS12615 37fa63a2be467890ae3fec2c6112294b 449 Pfam PF00082 Subtilase family 190 432 2.2E-55 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CIG75_RS12615 37fa63a2be467890ae3fec2c6112294b 449 SUPERFAMILY SSF52743 170 445 3.14E-99 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CIG75_RS12615 37fa63a2be467890ae3fec2c6112294b 449 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 230 240 - T 28-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site CIG75_RS12615 37fa63a2be467890ae3fec2c6112294b 449 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 193 204 - T 28-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site CIG75_RS14330 878b038604ab019c0b2a1dd7caa6488d 109 SMART SM00418 9 91 5.2E-15 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CIG75_RS14330 878b038604ab019c0b2a1dd7caa6488d 109 SUPERFAMILY SSF46785 4 100 1.84E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS14330 878b038604ab019c0b2a1dd7caa6488d 109 Pfam PF01022 Bacterial regulatory protein, arsR family 16 61 7.7E-10 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CIG75_RS14330 878b038604ab019c0b2a1dd7caa6488d 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 11 26 4.3E-10 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CIG75_RS14330 878b038604ab019c0b2a1dd7caa6488d 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 59 74 4.3E-10 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CIG75_RS14330 878b038604ab019c0b2a1dd7caa6488d 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 44 59 4.3E-10 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CIG75_RS14330 878b038604ab019c0b2a1dd7caa6488d 109 Gene3D G3DSA:1.10.10.10 1 109 1.1E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS16715 29787a39d249b8f873269d47e244a0b2 381 Gene3D G3DSA:3.40.50.150 161 373 5.8E-32 T 28-03-2018 CIG75_RS16715 29787a39d249b8f873269d47e244a0b2 381 Pfam PF01170 Putative RNA methylase family UPF0020 163 368 3.5E-56 T 28-03-2018 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CIG75_RS16715 29787a39d249b8f873269d47e244a0b2 381 ProSitePatterns PS01261 Uncharacterized protein family UPF0020 signature. 196 207 - T 28-03-2018 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CIG75_RS16715 29787a39d249b8f873269d47e244a0b2 381 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 300 306 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CIG75_RS16715 29787a39d249b8f873269d47e244a0b2 381 Pfam PF02926 THUMP domain 18 154 1.4E-12 T 28-03-2018 IPR004114 THUMP domain GO:0003723 CIG75_RS16715 29787a39d249b8f873269d47e244a0b2 381 SMART SM00981 58 155 1.1E-12 T 28-03-2018 IPR004114 THUMP domain GO:0003723 CIG75_RS16715 29787a39d249b8f873269d47e244a0b2 381 SUPERFAMILY SSF53335 255 372 7.75E-39 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CIG75_RS16715 29787a39d249b8f873269d47e244a0b2 381 SUPERFAMILY SSF53335 146 218 7.75E-39 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CIG75_RS02235 eae2484b5d5b3b7efa3868da277634a2 559 Gene3D G3DSA:1.10.287.950 311 557 2.9E-47 T 28-03-2018 CIG75_RS02235 eae2484b5d5b3b7efa3868da277634a2 559 Gene3D G3DSA:1.10.287.950 193 310 8.9E-9 T 28-03-2018 CIG75_RS02235 eae2484b5d5b3b7efa3868da277634a2 559 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 10 35 2.6E-20 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CIG75_RS02235 eae2484b5d5b3b7efa3868da277634a2 559 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 405 434 2.6E-20 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CIG75_RS02235 eae2484b5d5b3b7efa3868da277634a2 559 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 376 403 2.6E-20 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CIG75_RS02235 eae2484b5d5b3b7efa3868da277634a2 559 SMART SM00304 270 316 89.0 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CIG75_RS02235 eae2484b5d5b3b7efa3868da277634a2 559 SMART SM00304 196 249 0.0017 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CIG75_RS02235 eae2484b5d5b3b7efa3868da277634a2 559 SUPERFAMILY SSF58104 284 552 1.05E-62 T 28-03-2018 CIG75_RS02235 eae2484b5d5b3b7efa3868da277634a2 559 SUPERFAMILY SSF58104 227 251 1.05E-62 T 28-03-2018 CIG75_RS02235 eae2484b5d5b3b7efa3868da277634a2 559 SMART SM00283 278 553 8.5E-76 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CIG75_RS02235 eae2484b5d5b3b7efa3868da277634a2 559 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 323 506 2.2E-44 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CIG75_RS17080 59a340113d2b73c1e6cfd8bdf86c35e0 336 Gene3D G3DSA:3.30.360.10 162 315 2.7E-70 T 28-03-2018 CIG75_RS17080 59a340113d2b73c1e6cfd8bdf86c35e0 336 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 102 1.1E-41 T 28-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS17080 59a340113d2b73c1e6cfd8bdf86c35e0 336 SUPERFAMILY SSF55347 152 314 5.92E-74 T 28-03-2018 CIG75_RS17080 59a340113d2b73c1e6cfd8bdf86c35e0 336 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 157 313 3.4E-70 T 28-03-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS17080 59a340113d2b73c1e6cfd8bdf86c35e0 336 Gene3D G3DSA:3.40.50.720 1 161 6.0E-82 T 28-03-2018 CIG75_RS17080 59a340113d2b73c1e6cfd8bdf86c35e0 336 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 150 157 - T 28-03-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS17080 59a340113d2b73c1e6cfd8bdf86c35e0 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 229 246 4.4E-42 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS17080 59a340113d2b73c1e6cfd8bdf86c35e0 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 269 284 4.4E-42 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS17080 59a340113d2b73c1e6cfd8bdf86c35e0 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 109 122 4.4E-42 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS17080 59a340113d2b73c1e6cfd8bdf86c35e0 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 173 189 4.4E-42 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS17080 59a340113d2b73c1e6cfd8bdf86c35e0 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 146 164 4.4E-42 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS17080 59a340113d2b73c1e6cfd8bdf86c35e0 336 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 325 1.5E-139 T 28-03-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS17080 59a340113d2b73c1e6cfd8bdf86c35e0 336 SMART SM00846 3 152 1.5E-101 T 28-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS17080 59a340113d2b73c1e6cfd8bdf86c35e0 336 SUPERFAMILY SSF51735 3 170 1.56E-68 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS17080 59a340113d2b73c1e6cfd8bdf86c35e0 336 PIRSF PIRSF000149 1 334 6.4E-144 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS04410 b67c55174bc4694436c5c8c0e0c71e49 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 1.6E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS04410 b67c55174bc4694436c5c8c0e0c71e49 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 1.6E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS04410 b67c55174bc4694436c5c8c0e0c71e49 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 1.6E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS04410 b67c55174bc4694436c5c8c0e0c71e49 257 Gene3D G3DSA:3.40.50.720 1 45 7.0E-10 T 28-03-2018 CIG75_RS04410 b67c55174bc4694436c5c8c0e0c71e49 257 Gene3D G3DSA:3.40.50.720 46 248 2.3E-52 T 28-03-2018 CIG75_RS04410 b67c55174bc4694436c5c8c0e0c71e49 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 1.9E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS04410 b67c55174bc4694436c5c8c0e0c71e49 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 1.9E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS04410 b67c55174bc4694436c5c8c0e0c71e49 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 1.9E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS04410 b67c55174bc4694436c5c8c0e0c71e49 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.9E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS04410 b67c55174bc4694436c5c8c0e0c71e49 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 1.9E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS04410 b67c55174bc4694436c5c8c0e0c71e49 257 SUPERFAMILY SSF51735 3 244 2.47E-69 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS04410 b67c55174bc4694436c5c8c0e0c71e49 257 Pfam PF00106 short chain dehydrogenase 7 195 2.0E-56 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS04410 b67c55174bc4694436c5c8c0e0c71e49 257 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CIG75_RS04410 b67c55174bc4694436c5c8c0e0c71e49 257 PIRSF PIRSF000126 1 245 7.7E-53 T 28-03-2018 CIG75_RS07365 306bc72d9e69818df57ebaaf3195a766 396 PIRSF PIRSF001434 1 396 5.8E-143 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CIG75_RS07365 306bc72d9e69818df57ebaaf3195a766 396 Gene3D G3DSA:3.90.1150.10 263 396 1.1E-48 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CIG75_RS07365 306bc72d9e69818df57ebaaf3195a766 396 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 203 217 - T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CIG75_RS07365 306bc72d9e69818df57ebaaf3195a766 396 SUPERFAMILY SSF53383 29 395 3.54E-121 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CIG75_RS07365 306bc72d9e69818df57ebaaf3195a766 396 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 12 393 1.3E-139 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CIG75_RS07365 306bc72d9e69818df57ebaaf3195a766 396 Gene3D G3DSA:3.40.640.10 8 261 2.5E-64 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CIG75_RS07365 306bc72d9e69818df57ebaaf3195a766 396 TIGRFAM TIGR01328 met_gam_lyase: methionine gamma-lyase 8 396 4.3E-171 T 28-03-2018 IPR006237 L-methionine gamma-lyase GO:0018826 KEGG: 00270+4.4.1.11|KEGG: 00450+4.4.1.11|KEGG: 00920+4.4.1.2|MetaCyc: PWY-7793 CIG75_RS05910 2cc9edde8041d1ab20f5517f7aecf9db 439 Pfam PF01381 Helix-turn-helix 20 73 3.0E-11 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS05910 2cc9edde8041d1ab20f5517f7aecf9db 439 SUPERFAMILY SSF48452 78 266 3.22E-17 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS05910 2cc9edde8041d1ab20f5517f7aecf9db 439 Gene3D G3DSA:1.25.40.10 92 214 7.2E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS05910 2cc9edde8041d1ab20f5517f7aecf9db 439 Pfam PF13424 Tetratricopeptide repeat 202 266 3.2E-7 T 28-03-2018 CIG75_RS05910 2cc9edde8041d1ab20f5517f7aecf9db 439 Gene3D G3DSA:1.10.260.40 10 91 2.1E-15 T 28-03-2018 CIG75_RS05910 2cc9edde8041d1ab20f5517f7aecf9db 439 Gene3D G3DSA:1.25.40.10 215 252 7.3E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS05910 2cc9edde8041d1ab20f5517f7aecf9db 439 Gene3D G3DSA:1.25.40.10 253 350 1.7E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS05910 2cc9edde8041d1ab20f5517f7aecf9db 439 SUPERFAMILY SSF48452 277 422 1.93E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS05910 2cc9edde8041d1ab20f5517f7aecf9db 439 SUPERFAMILY SSF47413 15 74 1.04E-13 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CIG75_RS05910 2cc9edde8041d1ab20f5517f7aecf9db 439 SMART SM00028 358 391 69.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS05910 2cc9edde8041d1ab20f5517f7aecf9db 439 SMART SM00028 240 273 2.1 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS05910 2cc9edde8041d1ab20f5517f7aecf9db 439 SMART SM00028 202 235 0.1 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS05910 2cc9edde8041d1ab20f5517f7aecf9db 439 SMART SM00028 160 193 110.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS05910 2cc9edde8041d1ab20f5517f7aecf9db 439 SMART SM00028 320 353 160.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS05910 2cc9edde8041d1ab20f5517f7aecf9db 439 SMART SM00530 19 73 6.5E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS05910 2cc9edde8041d1ab20f5517f7aecf9db 439 Gene3D G3DSA:1.25.40.10 351 427 5.6E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS07345 cc869d3111ef94431a6ae034ec7a77d2 323 Pfam PF06725 3D domain 264 322 5.8E-13 T 28-03-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 CIG75_RS07345 cc869d3111ef94431a6ae034ec7a77d2 323 Gene3D G3DSA:2.40.40.10 23 322 1.2E-25 T 28-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CIG75_RS07345 cc869d3111ef94431a6ae034ec7a77d2 323 SUPERFAMILY SSF50685 264 309 2.89E-5 T 28-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CIG75_RS07345 cc869d3111ef94431a6ae034ec7a77d2 323 Pfam PF00395 S-layer homology domain 164 206 3.9E-5 T 28-03-2018 IPR001119 S-layer homology domain CIG75_RS07345 cc869d3111ef94431a6ae034ec7a77d2 323 Pfam PF00395 S-layer homology domain 32 73 8.1E-14 T 28-03-2018 IPR001119 S-layer homology domain CIG75_RS07345 cc869d3111ef94431a6ae034ec7a77d2 323 Pfam PF00395 S-layer homology domain 93 135 7.1E-8 T 28-03-2018 IPR001119 S-layer homology domain CIG75_RS18560 2753c029595b8eeb3ecf7b1a16253b28 325 SUPERFAMILY SSF53850 120 318 4.07E-35 T 28-03-2018 CIG75_RS18560 2753c029595b8eeb3ecf7b1a16253b28 325 Gene3D G3DSA:1.10.10.10 27 111 7.4E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS18560 2753c029595b8eeb3ecf7b1a16253b28 325 SUPERFAMILY SSF46785 24 139 6.53E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS18560 2753c029595b8eeb3ecf7b1a16253b28 325 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 68 79 2.1E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CIG75_RS18560 2753c029595b8eeb3ecf7b1a16253b28 325 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 58 68 2.1E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CIG75_RS18560 2753c029595b8eeb3ecf7b1a16253b28 325 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 47 58 2.1E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CIG75_RS18560 2753c029595b8eeb3ecf7b1a16253b28 325 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 34 91 9.5E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CIG75_RS18560 2753c029595b8eeb3ecf7b1a16253b28 325 Pfam PF03466 LysR substrate binding domain 118 313 4.2E-37 T 28-03-2018 IPR005119 LysR, substrate-binding CIG75_RS18560 2753c029595b8eeb3ecf7b1a16253b28 325 Gene3D G3DSA:3.40.190.10 204 291 1.6E-20 T 28-03-2018 CIG75_RS18560 2753c029595b8eeb3ecf7b1a16253b28 325 Gene3D G3DSA:3.40.190.10 120 203 8.5E-18 T 28-03-2018 CIG75_RS04825 a06c0b885c1f231ad38d1666ed28a201 293 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 58 100 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CIG75_RS04825 a06c0b885c1f231ad38d1666ed28a201 293 SMART SM00342 21 104 1.1E-28 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CIG75_RS04825 a06c0b885c1f231ad38d1666ed28a201 293 Gene3D G3DSA:1.10.10.60 1 57 1.4E-12 T 28-03-2018 CIG75_RS04825 a06c0b885c1f231ad38d1666ed28a201 293 SUPERFAMILY SSF46689 4 55 6.99E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CIG75_RS04825 a06c0b885c1f231ad38d1666ed28a201 293 Gene3D G3DSA:3.20.80.10 116 290 3.8E-46 T 28-03-2018 IPR011256 Regulatory factor, effector binding domain CIG75_RS04825 a06c0b885c1f231ad38d1666ed28a201 293 SUPERFAMILY SSF46689 57 110 1.21E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CIG75_RS04825 a06c0b885c1f231ad38d1666ed28a201 293 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 88 104 8.4E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CIG75_RS04825 a06c0b885c1f231ad38d1666ed28a201 293 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 73 88 8.4E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CIG75_RS04825 a06c0b885c1f231ad38d1666ed28a201 293 Pfam PF12833 Helix-turn-helix domain 27 105 9.4E-21 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CIG75_RS04825 a06c0b885c1f231ad38d1666ed28a201 293 SMART SM00871 131 291 3.5E-33 T 28-03-2018 IPR010499 Bacterial transcription activator, effector binding CIG75_RS04825 a06c0b885c1f231ad38d1666ed28a201 293 SUPERFAMILY SSF55136 131 292 8.63E-26 T 28-03-2018 CIG75_RS04825 a06c0b885c1f231ad38d1666ed28a201 293 Pfam PF14526 Integron-associated effector binding protein 134 290 1.9E-30 T 28-03-2018 IPR029441 Integron-associated effector binding protein CIG75_RS04825 a06c0b885c1f231ad38d1666ed28a201 293 Gene3D G3DSA:1.10.10.60 58 115 7.0E-16 T 28-03-2018 CIG75_RS01425 ec2603a55f44edc004e7304b99e08e93 395 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 235 248 - T 28-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CIG75_RS01425 ec2603a55f44edc004e7304b99e08e93 395 SUPERFAMILY SSF53383 5 391 2.93E-115 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CIG75_RS01425 ec2603a55f44edc004e7304b99e08e93 395 Pfam PF00155 Aminotransferase class I and II 33 387 4.8E-78 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CIG75_RS01425 ec2603a55f44edc004e7304b99e08e93 395 Gene3D G3DSA:3.90.1150.10 6 82 2.3E-4 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CIG75_RS01425 ec2603a55f44edc004e7304b99e08e93 395 Gene3D G3DSA:3.90.1150.10 285 394 5.6E-23 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CIG75_RS01425 ec2603a55f44edc004e7304b99e08e93 395 Gene3D G3DSA:3.40.640.10 83 284 1.2E-59 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CIG75_RS06770 5dc74479d859d33eac12f663ced7a680 597 SUPERFAMILY SSF55785 241 360 1.62E-18 T 28-03-2018 IPR000014 PAS domain CIG75_RS06770 5dc74479d859d33eac12f663ced7a680 597 Gene3D G3DSA:3.30.565.10 440 595 2.6E-39 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS06770 5dc74479d859d33eac12f663ced7a680 597 PRINTS PR00344 Bacterial sensor protein C-terminal signature 519 533 1.5E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS06770 5dc74479d859d33eac12f663ced7a680 597 PRINTS PR00344 Bacterial sensor protein C-terminal signature 537 547 1.5E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS06770 5dc74479d859d33eac12f663ced7a680 597 PRINTS PR00344 Bacterial sensor protein C-terminal signature 572 585 1.5E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS06770 5dc74479d859d33eac12f663ced7a680 597 PRINTS PR00344 Bacterial sensor protein C-terminal signature 548 566 1.5E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS06770 5dc74479d859d33eac12f663ced7a680 597 SUPERFAMILY SSF55874 440 588 2.75E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS06770 5dc74479d859d33eac12f663ced7a680 597 SMART SM00387 481 588 1.8E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS06770 5dc74479d859d33eac12f663ced7a680 597 Pfam PF08448 PAS fold 261 364 8.8E-12 T 28-03-2018 IPR013656 PAS fold-4 CIG75_RS06770 5dc74479d859d33eac12f663ced7a680 597 Gene3D G3DSA:3.30.450.20 240 367 8.3E-26 T 28-03-2018 CIG75_RS06770 5dc74479d859d33eac12f663ced7a680 597 SMART SM00091 254 320 4.0E-11 T 28-03-2018 IPR000014 PAS domain CIG75_RS06770 5dc74479d859d33eac12f663ced7a680 597 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 252 368 3.6E-18 T 28-03-2018 IPR000014 PAS domain CIG75_RS06770 5dc74479d859d33eac12f663ced7a680 597 Gene3D G3DSA:1.10.287.130 368 436 5.5E-16 T 28-03-2018 CIG75_RS06770 5dc74479d859d33eac12f663ced7a680 597 SMART SM00388 377 440 3.7E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CIG75_RS06770 5dc74479d859d33eac12f663ced7a680 597 SUPERFAMILY SSF47384 373 441 5.1E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CIG75_RS06770 5dc74479d859d33eac12f663ced7a680 597 Pfam PF00512 His Kinase A (phospho-acceptor) domain 379 439 4.3E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CIG75_RS06770 5dc74479d859d33eac12f663ced7a680 597 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 483 587 1.6E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS04110 ec0ce59b81dbd862478134ff0361d138 181 SUPERFAMILY SSF54001 42 167 1.49E-12 T 28-03-2018 CIG75_RS04110 ec0ce59b81dbd862478134ff0361d138 181 Pfam PF05708 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family 51 153 3.8E-7 T 28-03-2018 IPR024453 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family CIG75_RS04110 ec0ce59b81dbd862478134ff0361d138 181 Gene3D G3DSA:3.90.1720.10 36 179 3.8E-9 T 28-03-2018 CIG75_RS02280 20421bfc4ac6b97d0a8ab9c13f91af82 600 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 482 592 5.9E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS02280 20421bfc4ac6b97d0a8ab9c13f91af82 600 Gene3D G3DSA:3.30.450.20 30 166 1.5E-17 T 28-03-2018 CIG75_RS02280 20421bfc4ac6b97d0a8ab9c13f91af82 600 SUPERFAMILY SSF55874 424 591 1.96E-53 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS02280 20421bfc4ac6b97d0a8ab9c13f91af82 600 SUPERFAMILY SSF47384 353 436 2.75E-23 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CIG75_RS02280 20421bfc4ac6b97d0a8ab9c13f91af82 600 SUPERFAMILY SSF55785 243 355 8.72E-16 T 28-03-2018 IPR000014 PAS domain CIG75_RS02280 20421bfc4ac6b97d0a8ab9c13f91af82 600 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 254 367 2.4E-12 T 28-03-2018 IPR000014 PAS domain CIG75_RS02280 20421bfc4ac6b97d0a8ab9c13f91af82 600 SMART SM00091 253 320 7.0E-6 T 28-03-2018 IPR000014 PAS domain CIG75_RS02280 20421bfc4ac6b97d0a8ab9c13f91af82 600 SMART SM00304 194 246 1.0E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CIG75_RS02280 20421bfc4ac6b97d0a8ab9c13f91af82 600 Gene3D G3DSA:3.30.450.20 248 373 6.7E-23 T 28-03-2018 CIG75_RS02280 20421bfc4ac6b97d0a8ab9c13f91af82 600 Pfam PF16736 Single Cache-like 35 157 6.3E-8 T 28-03-2018 IPR031967 PhoR, single Cache-like domain CIG75_RS02280 20421bfc4ac6b97d0a8ab9c13f91af82 600 SMART SM00387 481 593 1.9E-44 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS02280 20421bfc4ac6b97d0a8ab9c13f91af82 600 Pfam PF00672 HAMP domain 196 242 3.3E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CIG75_RS02280 20421bfc4ac6b97d0a8ab9c13f91af82 600 SMART SM00388 368 435 5.2E-27 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CIG75_RS02280 20421bfc4ac6b97d0a8ab9c13f91af82 600 Gene3D G3DSA:3.30.565.10 439 600 1.5E-52 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS02280 20421bfc4ac6b97d0a8ab9c13f91af82 600 PRINTS PR00344 Bacterial sensor protein C-terminal signature 536 546 1.3E-21 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS02280 20421bfc4ac6b97d0a8ab9c13f91af82 600 PRINTS PR00344 Bacterial sensor protein C-terminal signature 518 532 1.3E-21 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS02280 20421bfc4ac6b97d0a8ab9c13f91af82 600 PRINTS PR00344 Bacterial sensor protein C-terminal signature 577 590 1.3E-21 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS02280 20421bfc4ac6b97d0a8ab9c13f91af82 600 PRINTS PR00344 Bacterial sensor protein C-terminal signature 553 571 1.3E-21 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS02280 20421bfc4ac6b97d0a8ab9c13f91af82 600 Pfam PF08448 PAS fold 259 363 1.5E-11 T 28-03-2018 IPR013656 PAS fold-4 CIG75_RS02280 20421bfc4ac6b97d0a8ab9c13f91af82 600 Gene3D G3DSA:1.10.287.130 374 431 2.8E-21 T 28-03-2018 CIG75_RS02280 20421bfc4ac6b97d0a8ab9c13f91af82 600 Pfam PF00512 His Kinase A (phospho-acceptor) domain 368 435 1.1E-22 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CIG75_RS02280 20421bfc4ac6b97d0a8ab9c13f91af82 600 SUPERFAMILY SSF158472 196 245 6.93E-9 T 28-03-2018 CIG75_RS05675 a8151a2719baff78d5dda89904efd763 297 SUPERFAMILY SSF53187 39 224 5.65E-48 T 28-03-2018 CIG75_RS05675 a8151a2719baff78d5dda89904efd763 297 SMART SM00646 106 218 7.8E-32 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CIG75_RS05675 a8151a2719baff78d5dda89904efd763 297 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 40 217 3.6E-46 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CIG75_RS05675 a8151a2719baff78d5dda89904efd763 297 Pfam PF00395 S-layer homology domain 246 283 1.2E-8 T 28-03-2018 IPR001119 S-layer homology domain CIG75_RS05675 a8151a2719baff78d5dda89904efd763 297 Gene3D G3DSA:3.40.630.40 37 227 2.2E-52 T 28-03-2018 CIG75_RS00830 2769f821fc7a9e911596d2b7fcbc01db 208 Gene3D G3DSA:3.40.50.2020 1 208 3.9E-32 T 28-03-2018 CIG75_RS00830 2769f821fc7a9e911596d2b7fcbc01db 208 SUPERFAMILY SSF53271 6 199 2.88E-44 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CIG75_RS00830 2769f821fc7a9e911596d2b7fcbc01db 208 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 12 179 2.9E-36 T 28-03-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CIG75_RS00830 2769f821fc7a9e911596d2b7fcbc01db 208 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 208 25.201 T 28-03-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CIG75_RS00830 2769f821fc7a9e911596d2b7fcbc01db 208 Pfam PF00156 Phosphoribosyl transferase domain 49 169 6.1E-14 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CIG75_RS06605 a2250974d7c0be22d6e078ddb9db0a0a 1865 Gene3D G3DSA:1.10.1200.10 1770 1845 1.2E-20 T 28-03-2018 CIG75_RS06605 a2250974d7c0be22d6e078ddb9db0a0a 1865 Pfam PF00550 Phosphopantetheine attachment site 1767 1827 7.4E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS06605 a2250974d7c0be22d6e078ddb9db0a0a 1865 Pfam PF00550 Phosphopantetheine attachment site 687 748 1.2E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS06605 a2250974d7c0be22d6e078ddb9db0a0a 1865 SMART SM00823 Phosphopantetheine attachment site 684 753 2.0E-6 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS06605 a2250974d7c0be22d6e078ddb9db0a0a 1865 SMART SM00823 Phosphopantetheine attachment site 1764 1833 0.0017 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS06605 a2250974d7c0be22d6e078ddb9db0a0a 1865 Gene3D G3DSA:3.30.559.10 794 1006 4.6E-47 T 28-03-2018 CIG75_RS06605 a2250974d7c0be22d6e078ddb9db0a0a 1865 Gene3D G3DSA:3.40.50.980 172 324 1.2E-50 T 28-03-2018 CIG75_RS06605 a2250974d7c0be22d6e078ddb9db0a0a 1865 SUPERFAMILY SSF56801 1227 1777 5.36E-164 T 28-03-2018 CIG75_RS06605 a2250974d7c0be22d6e078ddb9db0a0a 1865 Gene3D G3DSA:3.40.50.980 325 482 9.4E-34 T 28-03-2018 CIG75_RS06605 a2250974d7c0be22d6e078ddb9db0a0a 1865 Gene3D G3DSA:3.40.50.980 1416 1575 1.6E-42 T 28-03-2018 CIG75_RS06605 a2250974d7c0be22d6e078ddb9db0a0a 1865 SUPERFAMILY SSF52777 819 983 3.34E-51 T 28-03-2018 CIG75_RS06605 a2250974d7c0be22d6e078ddb9db0a0a 1865 Gene3D G3DSA:2.30.38.10 1576 1655 6.1E-24 T 28-03-2018 CIG75_RS06605 a2250974d7c0be22d6e078ddb9db0a0a 1865 SUPERFAMILY SSF52777 991 1231 9.45E-65 T 28-03-2018 CIG75_RS06605 a2250974d7c0be22d6e078ddb9db0a0a 1865 SUPERFAMILY SSF47336 676 749 5.37E-18 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS06605 a2250974d7c0be22d6e078ddb9db0a0a 1865 ProSitePatterns PS00012 Phosphopantetheine attachment site. 708 723 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS06605 a2250974d7c0be22d6e078ddb9db0a0a 1865 Pfam PF13193 AMP-binding enzyme C-terminal domain 581 656 6.9E-14 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS06605 a2250974d7c0be22d6e078ddb9db0a0a 1865 Pfam PF13193 AMP-binding enzyme C-terminal domain 1670 1738 9.7E-11 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS06605 a2250974d7c0be22d6e078ddb9db0a0a 1865 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1411 1422 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS06605 a2250974d7c0be22d6e078ddb9db0a0a 1865 Gene3D G3DSA:3.30.300.30 568 687 2.0E-40 T 28-03-2018 CIG75_RS06605 a2250974d7c0be22d6e078ddb9db0a0a 1865 Gene3D G3DSA:3.30.300.30 1657 1769 2.1E-35 T 28-03-2018 CIG75_RS06605 a2250974d7c0be22d6e078ddb9db0a0a 1865 Gene3D G3DSA:2.30.38.10 483 563 8.7E-26 T 28-03-2018 CIG75_RS06605 a2250974d7c0be22d6e078ddb9db0a0a 1865 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1788 1803 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS06605 a2250974d7c0be22d6e078ddb9db0a0a 1865 Pfam PF00501 AMP-binding enzyme 1269 1662 9.0E-109 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS06605 a2250974d7c0be22d6e078ddb9db0a0a 1865 Pfam PF00501 AMP-binding enzyme 181 573 5.7E-102 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS06605 a2250974d7c0be22d6e078ddb9db0a0a 1865 Pfam PF00668 Condensation domain 816 1243 4.8E-116 T 28-03-2018 IPR001242 Condensation domain CIG75_RS06605 a2250974d7c0be22d6e078ddb9db0a0a 1865 Gene3D G3DSA:3.40.50.980 1263 1415 1.3E-47 T 28-03-2018 CIG75_RS06605 a2250974d7c0be22d6e078ddb9db0a0a 1865 Gene3D G3DSA:1.10.1200.10 688 762 6.6E-22 T 28-03-2018 CIG75_RS06605 a2250974d7c0be22d6e078ddb9db0a0a 1865 SUPERFAMILY SSF47336 1757 1829 1.83E-18 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS06605 a2250974d7c0be22d6e078ddb9db0a0a 1865 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 202 596 1.0E-134 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS06605 a2250974d7c0be22d6e078ddb9db0a0a 1865 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1290 1686 9.7E-142 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS06605 a2250974d7c0be22d6e078ddb9db0a0a 1865 SUPERFAMILY SSF56801 150 697 3.79E-161 T 28-03-2018 CIG75_RS06605 a2250974d7c0be22d6e078ddb9db0a0a 1865 ProSitePatterns PS00455 Putative AMP-binding domain signature. 319 330 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS09195 e4979bf5f83c01f668c25b48063c9056 1030 Gene3D G3DSA:3.30.70.1430 562 662 5.9E-19 T 28-03-2018 CIG75_RS09195 e4979bf5f83c01f668c25b48063c9056 1030 Gene3D G3DSA:3.30.70.1430 40 140 1.4E-22 T 28-03-2018 CIG75_RS09195 e4979bf5f83c01f668c25b48063c9056 1030 SUPERFAMILY SSF82693 41 133 5.93E-23 T 28-03-2018 CIG75_RS09195 e4979bf5f83c01f668c25b48063c9056 1030 SUPERFAMILY SSF82866 797 1021 4.05E-52 T 28-03-2018 CIG75_RS09195 e4979bf5f83c01f668c25b48063c9056 1030 SUPERFAMILY SSF82866 288 488 1.7E-43 T 28-03-2018 CIG75_RS09195 e4979bf5f83c01f668c25b48063c9056 1030 Gene3D G3DSA:1.20.1640.10 809 1023 3.2E-40 T 28-03-2018 CIG75_RS09195 e4979bf5f83c01f668c25b48063c9056 1030 Gene3D G3DSA:1.20.1640.10 263 489 1.6E-44 T 28-03-2018 CIG75_RS09195 e4979bf5f83c01f668c25b48063c9056 1030 SUPERFAMILY SSF82693 561 659 3.4E-15 T 28-03-2018 CIG75_RS09195 e4979bf5f83c01f668c25b48063c9056 1030 Gene3D G3DSA:3.30.2090.10 714 801 3.9E-19 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CIG75_RS09195 e4979bf5f83c01f668c25b48063c9056 1030 Gene3D G3DSA:3.30.2090.10 178 262 8.2E-14 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CIG75_RS09195 e4979bf5f83c01f668c25b48063c9056 1030 Pfam PF00873 AcrB/AcrD/AcrF family 4 1019 4.9E-252 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CIG75_RS09195 e4979bf5f83c01f668c25b48063c9056 1030 SUPERFAMILY SSF82693 265 320 2.09E-18 T 28-03-2018 CIG75_RS09195 e4979bf5f83c01f668c25b48063c9056 1030 SUPERFAMILY SSF82693 135 179 2.09E-18 T 28-03-2018 CIG75_RS09195 e4979bf5f83c01f668c25b48063c9056 1030 SUPERFAMILY SSF82714 715 799 8.5E-15 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CIG75_RS09195 e4979bf5f83c01f668c25b48063c9056 1030 SUPERFAMILY SSF82714 182 261 6.15E-11 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CIG75_RS09195 e4979bf5f83c01f668c25b48063c9056 1030 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 4.9E-51 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CIG75_RS09195 e4979bf5f83c01f668c25b48063c9056 1030 PRINTS PR00702 Acriflavin resistance protein family signature 327 350 4.9E-51 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CIG75_RS09195 e4979bf5f83c01f668c25b48063c9056 1030 PRINTS PR00702 Acriflavin resistance protein family signature 382 406 4.9E-51 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CIG75_RS09195 e4979bf5f83c01f668c25b48063c9056 1030 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 4.9E-51 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CIG75_RS09195 e4979bf5f83c01f668c25b48063c9056 1030 PRINTS PR00702 Acriflavin resistance protein family signature 547 564 4.9E-51 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CIG75_RS09195 e4979bf5f83c01f668c25b48063c9056 1030 PRINTS PR00702 Acriflavin resistance protein family signature 619 633 4.9E-51 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CIG75_RS09195 e4979bf5f83c01f668c25b48063c9056 1030 PRINTS PR00702 Acriflavin resistance protein family signature 354 375 4.9E-51 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CIG75_RS09195 e4979bf5f83c01f668c25b48063c9056 1030 PRINTS PR00702 Acriflavin resistance protein family signature 460 483 4.9E-51 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CIG75_RS09195 e4979bf5f83c01f668c25b48063c9056 1030 PRINTS PR00702 Acriflavin resistance protein family signature 435 458 4.9E-51 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CIG75_RS07120 54fa4099539e9367de0877353865c3c9 83 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 6 65 3.1E-22 T 28-03-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 CIG75_RS07120 54fa4099539e9367de0877353865c3c9 83 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 20 29 - T 28-03-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 CIG75_RS12060 8a981d39874029918f804da1bdd4979e 337 SUPERFAMILY SSF48029 9 103 1.75E-23 T 28-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical CIG75_RS12060 8a981d39874029918f804da1bdd4979e 337 Pfam PF01706 FliG C-terminal domain 220 327 6.8E-44 T 28-03-2018 IPR023087 Flagellar motor switch protein FliG, C-terminal CIG75_RS12060 8a981d39874029918f804da1bdd4979e 337 Pfam PF14842 FliG N-terminal domain 7 110 6.4E-39 T 28-03-2018 IPR028263 Flagellar motor switch protein FliG, N-terminal domain CIG75_RS12060 8a981d39874029918f804da1bdd4979e 337 Gene3D G3DSA:1.10.220.30 198 337 2.1E-39 T 28-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical CIG75_RS12060 8a981d39874029918f804da1bdd4979e 337 Gene3D G3DSA:1.10.220.30 2 86 6.9E-15 T 28-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical CIG75_RS12060 8a981d39874029918f804da1bdd4979e 337 Gene3D G3DSA:1.10.220.30 87 193 8.9E-22 T 28-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical CIG75_RS12060 8a981d39874029918f804da1bdd4979e 337 PRINTS PR00954 Flagellar motor switch protein FliG signature 8 24 1.2E-79 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CIG75_RS12060 8a981d39874029918f804da1bdd4979e 337 PRINTS PR00954 Flagellar motor switch protein FliG signature 117 140 1.2E-79 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CIG75_RS12060 8a981d39874029918f804da1bdd4979e 337 PRINTS PR00954 Flagellar motor switch protein FliG signature 229 249 1.2E-79 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CIG75_RS12060 8a981d39874029918f804da1bdd4979e 337 PRINTS PR00954 Flagellar motor switch protein FliG signature 251 271 1.2E-79 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CIG75_RS12060 8a981d39874029918f804da1bdd4979e 337 PRINTS PR00954 Flagellar motor switch protein FliG signature 275 301 1.2E-79 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CIG75_RS12060 8a981d39874029918f804da1bdd4979e 337 PRINTS PR00954 Flagellar motor switch protein FliG signature 198 223 1.2E-79 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CIG75_RS12060 8a981d39874029918f804da1bdd4979e 337 PRINTS PR00954 Flagellar motor switch protein FliG signature 37 63 1.2E-79 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CIG75_RS12060 8a981d39874029918f804da1bdd4979e 337 TIGRFAM TIGR00207 fliG: flagellar motor switch protein FliG 4 337 6.7E-150 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CIG75_RS12060 8a981d39874029918f804da1bdd4979e 337 SUPERFAMILY SSF48029 117 328 2.49E-70 T 28-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical CIG75_RS12060 8a981d39874029918f804da1bdd4979e 337 PIRSF PIRSF003161 2 337 4.9E-123 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CIG75_RS12060 8a981d39874029918f804da1bdd4979e 337 Pfam PF14841 FliG middle domain 118 190 1.1E-31 T 28-03-2018 IPR032779 Flagellar motor switch protein FliG, middle domain CIG75_RS00455 2521503c6e71cba0f6d8cbe50c6b4da6 577 ProSitePatterns PS00211 ABC transporters family signature. 421 435 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS00455 2521503c6e71cba0f6d8cbe50c6b4da6 577 SUPERFAMILY SSF52540 5 200 2.67E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS00455 2521503c6e71cba0f6d8cbe50c6b4da6 577 SMART SM00382 329 494 4.1E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS00455 2521503c6e71cba0f6d8cbe50c6b4da6 577 SMART SM00382 29 188 6.3E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS00455 2521503c6e71cba0f6d8cbe50c6b4da6 577 Gene3D G3DSA:3.40.50.300 291 574 1.6E-44 T 28-03-2018 CIG75_RS00455 2521503c6e71cba0f6d8cbe50c6b4da6 577 Pfam PF00005 ABC transporter 320 449 5.5E-20 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS00455 2521503c6e71cba0f6d8cbe50c6b4da6 577 Pfam PF00005 ABC transporter 21 143 1.1E-19 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS00455 2521503c6e71cba0f6d8cbe50c6b4da6 577 SUPERFAMILY SSF52540 301 498 3.23E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS00455 2521503c6e71cba0f6d8cbe50c6b4da6 577 Pfam PF12848 ABC transporter 182 243 1.2E-7 T 28-03-2018 IPR032781 ABC-transporter extension domain CIG75_RS00455 2521503c6e71cba0f6d8cbe50c6b4da6 577 ProSitePatterns PS00211 ABC transporters family signature. 115 129 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS00455 2521503c6e71cba0f6d8cbe50c6b4da6 577 Gene3D G3DSA:3.40.50.300 1 290 6.5E-47 T 28-03-2018 CIG75_RS11725 e31d1f623e9f62ab41379795ee785402 345 SUPERFAMILY SSF55347 131 329 6.05E-77 T 28-03-2018 CIG75_RS11725 e31d1f623e9f62ab41379795ee785402 345 Gene3D G3DSA:3.30.360.10 144 324 8.0E-74 T 28-03-2018 CIG75_RS11725 e31d1f623e9f62ab41379795ee785402 345 PIRSF PIRSF000148 6 345 7.2E-136 T 28-03-2018 CIG75_RS11725 e31d1f623e9f62ab41379795ee785402 345 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 141 328 4.1E-56 T 28-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CIG75_RS11725 e31d1f623e9f62ab41379795ee785402 345 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 8 122 1.6E-33 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CIG75_RS11725 e31d1f623e9f62ab41379795ee785402 345 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 6 342 38.509 T 28-03-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CIG75_RS11725 e31d1f623e9f62ab41379795ee785402 345 Gene3D G3DSA:3.40.50.720 3 143 6.5E-37 T 28-03-2018 CIG75_RS11725 e31d1f623e9f62ab41379795ee785402 345 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 8 343 2.1E-146 T 28-03-2018 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CIG75_RS11725 e31d1f623e9f62ab41379795ee785402 345 SUPERFAMILY SSF51735 7 159 6.5E-54 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS11725 e31d1f623e9f62ab41379795ee785402 345 SMART SM00859 8 123 3.6E-44 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CIG75_RS14115 f3154aac584d7b9a40b3a964266df9fd 415 Gene3D G3DSA:3.50.50.60 3 203 7.1E-28 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS14115 f3154aac584d7b9a40b3a964266df9fd 415 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 159 168 7.9E-7 T 28-03-2018 CIG75_RS14115 f3154aac584d7b9a40b3a964266df9fd 415 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 7.9E-7 T 28-03-2018 CIG75_RS14115 f3154aac584d7b9a40b3a964266df9fd 415 SUPERFAMILY SSF160996 193 358 1.01E-45 T 28-03-2018 CIG75_RS14115 f3154aac584d7b9a40b3a964266df9fd 415 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 365 387 8.2E-6 T 28-03-2018 CIG75_RS14115 f3154aac584d7b9a40b3a964266df9fd 415 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 156 174 8.2E-6 T 28-03-2018 CIG75_RS14115 f3154aac584d7b9a40b3a964266df9fd 415 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 8.2E-6 T 28-03-2018 CIG75_RS14115 f3154aac584d7b9a40b3a964266df9fd 415 SUPERFAMILY SSF51905 355 414 4.33E-59 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS14115 f3154aac584d7b9a40b3a964266df9fd 415 SUPERFAMILY SSF51905 1 194 4.33E-59 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS14115 f3154aac584d7b9a40b3a964266df9fd 415 Gene3D G3DSA:1.10.8.260 285 339 1.7E-5 T 28-03-2018 IPR023166 HI0933 insert-like domain CIG75_RS14115 f3154aac584d7b9a40b3a964266df9fd 415 Pfam PF03486 HI0933-like protein 4 410 2.0E-149 T 28-03-2018 CIG75_RS14115 f3154aac584d7b9a40b3a964266df9fd 415 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 5 410 6.9E-146 T 28-03-2018 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like CIG75_RS14115 f3154aac584d7b9a40b3a964266df9fd 415 Gene3D G3DSA:2.40.30.10 204 284 5.0E-23 T 28-03-2018 CIG75_RS09880 692608a9c0526eb3759d37ac5cfab689 474 Pfam PF13394 4Fe-4S single cluster domain 105 184 5.0E-8 T 28-03-2018 CIG75_RS09880 692608a9c0526eb3759d37ac5cfab689 474 Gene3D G3DSA:3.20.20.70 91 454 6.4E-31 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CIG75_RS09880 692608a9c0526eb3759d37ac5cfab689 474 SMART SM00729 97 301 0.0077 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CIG75_RS09880 692608a9c0526eb3759d37ac5cfab689 474 Pfam PF04055 Radical SAM superfamily 102 261 2.7E-22 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CIG75_RS09880 692608a9c0526eb3759d37ac5cfab689 474 SUPERFAMILY SSF102114 86 301 2.35E-37 T 28-03-2018 CIG75_RS12545 815ca0fed8b42df2b78bc3d9e80ab6e5 275 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 62 76 - T 28-03-2018 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CIG75_RS12545 815ca0fed8b42df2b78bc3d9e80ab6e5 275 Pfam PF01678 Diaminopimelate epimerase 155 269 2.9E-31 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CIG75_RS12545 815ca0fed8b42df2b78bc3d9e80ab6e5 275 Pfam PF01678 Diaminopimelate epimerase 3 124 1.8E-32 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CIG75_RS12545 815ca0fed8b42df2b78bc3d9e80ab6e5 275 Gene3D G3DSA:3.10.310.10 1 126 1.4E-50 T 28-03-2018 CIG75_RS12545 815ca0fed8b42df2b78bc3d9e80ab6e5 275 SUPERFAMILY SSF54506 1 275 1.23E-52 T 28-03-2018 CIG75_RS12545 815ca0fed8b42df2b78bc3d9e80ab6e5 275 Gene3D G3DSA:3.10.310.10 127 264 1.7E-52 T 28-03-2018 CIG75_RS12545 815ca0fed8b42df2b78bc3d9e80ab6e5 275 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 1 274 4.6E-95 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CIG75_RS12545 815ca0fed8b42df2b78bc3d9e80ab6e5 275 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 1 275 37.972 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CIG75_RS09770 2f69df3e2f0f969b2aefdbfd3856c6ed 437 SUPERFAMILY SSF118215 26 415 3.14E-109 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CIG75_RS09770 2f69df3e2f0f969b2aefdbfd3856c6ed 437 PRINTS PR00173 Glutamate-aspartate symporter signature 90 115 4.6E-23 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CIG75_RS09770 2f69df3e2f0f969b2aefdbfd3856c6ed 437 PRINTS PR00173 Glutamate-aspartate symporter signature 23 43 4.6E-23 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CIG75_RS09770 2f69df3e2f0f969b2aefdbfd3856c6ed 437 PRINTS PR00173 Glutamate-aspartate symporter signature 230 249 4.6E-23 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CIG75_RS09770 2f69df3e2f0f969b2aefdbfd3856c6ed 437 PRINTS PR00173 Glutamate-aspartate symporter signature 369 389 4.6E-23 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CIG75_RS09770 2f69df3e2f0f969b2aefdbfd3856c6ed 437 PRINTS PR00173 Glutamate-aspartate symporter signature 204 223 4.6E-23 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CIG75_RS09770 2f69df3e2f0f969b2aefdbfd3856c6ed 437 PRINTS PR00173 Glutamate-aspartate symporter signature 306 332 4.6E-23 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CIG75_RS09770 2f69df3e2f0f969b2aefdbfd3856c6ed 437 Pfam PF00375 Sodium:dicarboxylate symporter family 27 414 2.9E-120 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CIG75_RS09770 2f69df3e2f0f969b2aefdbfd3856c6ed 437 Gene3D G3DSA:1.10.3860.10 14 422 5.7E-113 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CIG75_RS12030 07cc3d4248595baffec4f336dd88b419 136 Pfam PF03963 Flagellar hook capping protein - N-terminal region 14 68 4.2E-20 T 28-03-2018 IPR005648 Flagellar hook capping protein CIG75_RS10475 419b4c01ca0bbc7d4b9d0bdd75bd5d92 2391 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1674 1685 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS10475 419b4c01ca0bbc7d4b9d0bdd75bd5d92 2391 Pfam PF13193 AMP-binding enzyme C-terminal domain 1938 2013 2.2E-12 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS10475 419b4c01ca0bbc7d4b9d0bdd75bd5d92 2391 Pfam PF13193 AMP-binding enzyme C-terminal domain 882 955 1.6E-9 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS10475 419b4c01ca0bbc7d4b9d0bdd75bd5d92 2391 SUPERFAMILY SSF53474 2109 2381 7.6E-54 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS10475 419b4c01ca0bbc7d4b9d0bdd75bd5d92 2391 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1006 1021 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS10475 419b4c01ca0bbc7d4b9d0bdd75bd5d92 2391 Gene3D G3DSA:3.40.50.980 1680 1843 2.0E-35 T 28-03-2018 CIG75_RS10475 419b4c01ca0bbc7d4b9d0bdd75bd5d92 2391 Gene3D G3DSA:3.40.50.980 612 776 6.8E-35 T 28-03-2018 CIG75_RS10475 419b4c01ca0bbc7d4b9d0bdd75bd5d92 2391 Pfam PF00975 Thioesterase domain 2128 2378 5.6E-29 T 28-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CIG75_RS10475 419b4c01ca0bbc7d4b9d0bdd75bd5d92 2391 SMART SM00824 Thioesterase 2130 2381 0.0012 T 28-03-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 CIG75_RS10475 419b4c01ca0bbc7d4b9d0bdd75bd5d92 2391 Gene3D G3DSA:3.40.50.1820 2110 2380 2.0E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS10475 419b4c01ca0bbc7d4b9d0bdd75bd5d92 2391 SUPERFAMILY SSF47336 975 1047 1.57E-18 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10475 419b4c01ca0bbc7d4b9d0bdd75bd5d92 2391 ProSitePatterns PS00455 Putative AMP-binding domain signature. 606 617 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS10475 419b4c01ca0bbc7d4b9d0bdd75bd5d92 2391 Gene3D G3DSA:1.10.1200.10 2043 2109 2.4E-21 T 28-03-2018 CIG75_RS10475 419b4c01ca0bbc7d4b9d0bdd75bd5d92 2391 SUPERFAMILY SSF52777 1071 1248 1.11E-48 T 28-03-2018 CIG75_RS10475 419b4c01ca0bbc7d4b9d0bdd75bd5d92 2391 SMART SM00823 Phosphopantetheine attachment site 982 1051 0.0048 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS10475 419b4c01ca0bbc7d4b9d0bdd75bd5d92 2391 SMART SM00823 Phosphopantetheine attachment site 2039 2108 8.3E-5 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS10475 419b4c01ca0bbc7d4b9d0bdd75bd5d92 2391 Pfam PF00668 Condensation domain 10 439 7.6E-58 T 28-03-2018 IPR001242 Condensation domain CIG75_RS10475 419b4c01ca0bbc7d4b9d0bdd75bd5d92 2391 Pfam PF00668 Condensation domain 1066 1509 4.7E-115 T 28-03-2018 IPR001242 Condensation domain CIG75_RS10475 419b4c01ca0bbc7d4b9d0bdd75bd5d92 2391 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2063 2078 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS10475 419b4c01ca0bbc7d4b9d0bdd75bd5d92 2391 SUPERFAMILY SSF52777 1256 1495 8.34E-63 T 28-03-2018 CIG75_RS10475 419b4c01ca0bbc7d4b9d0bdd75bd5d92 2391 SUPERFAMILY SSF56801 419 993 5.89E-159 T 28-03-2018 CIG75_RS10475 419b4c01ca0bbc7d4b9d0bdd75bd5d92 2391 Gene3D G3DSA:3.40.50.980 454 611 2.2E-45 T 28-03-2018 CIG75_RS10475 419b4c01ca0bbc7d4b9d0bdd75bd5d92 2391 Gene3D G3DSA:3.40.50.980 1523 1679 9.4E-49 T 28-03-2018 CIG75_RS10475 419b4c01ca0bbc7d4b9d0bdd75bd5d92 2391 Pfam PF00550 Phosphopantetheine attachment site 2043 2104 2.0E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10475 419b4c01ca0bbc7d4b9d0bdd75bd5d92 2391 Pfam PF00550 Phosphopantetheine attachment site 984 1046 1.5E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10475 419b4c01ca0bbc7d4b9d0bdd75bd5d92 2391 Gene3D G3DSA:3.30.300.30 870 987 9.0E-38 T 28-03-2018 CIG75_RS10475 419b4c01ca0bbc7d4b9d0bdd75bd5d92 2391 Gene3D G3DSA:3.30.300.30 1925 2042 1.2E-39 T 28-03-2018 CIG75_RS10475 419b4c01ca0bbc7d4b9d0bdd75bd5d92 2391 Gene3D G3DSA:2.30.38.10 1844 1923 5.7E-21 T 28-03-2018 CIG75_RS10475 419b4c01ca0bbc7d4b9d0bdd75bd5d92 2391 SUPERFAMILY SSF56801 1489 2051 2.88E-157 T 28-03-2018 CIG75_RS10475 419b4c01ca0bbc7d4b9d0bdd75bd5d92 2391 Gene3D G3DSA:2.30.38.10 782 864 2.2E-26 T 28-03-2018 CIG75_RS10475 419b4c01ca0bbc7d4b9d0bdd75bd5d92 2391 Pfam PF00501 AMP-binding enzyme 1532 1930 2.3E-102 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS10475 419b4c01ca0bbc7d4b9d0bdd75bd5d92 2391 Pfam PF00501 AMP-binding enzyme 464 874 3.0E-97 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS10475 419b4c01ca0bbc7d4b9d0bdd75bd5d92 2391 Gene3D G3DSA:3.30.559.10 1050 1256 7.9E-39 T 28-03-2018 CIG75_RS10475 419b4c01ca0bbc7d4b9d0bdd75bd5d92 2391 Gene3D G3DSA:3.30.559.10 2 201 2.0E-22 T 28-03-2018 CIG75_RS10475 419b4c01ca0bbc7d4b9d0bdd75bd5d92 2391 SUPERFAMILY SSF47336 2031 2105 9.29E-18 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10475 419b4c01ca0bbc7d4b9d0bdd75bd5d92 2391 Gene3D G3DSA:1.10.1200.10 988 1049 1.0E-21 T 28-03-2018 CIG75_RS10475 419b4c01ca0bbc7d4b9d0bdd75bd5d92 2391 SUPERFAMILY SSF52777 7 205 5.0E-28 T 28-03-2018 CIG75_RS10475 419b4c01ca0bbc7d4b9d0bdd75bd5d92 2391 SUPERFAMILY SSF52777 191 430 2.67E-37 T 28-03-2018 CIG75_RS10475 419b4c01ca0bbc7d4b9d0bdd75bd5d92 2391 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1553 1954 2.9E-122 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS10475 419b4c01ca0bbc7d4b9d0bdd75bd5d92 2391 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 484 897 2.3E-125 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS08935 ab3176cd7791980f9e1aab417584cac0 502 PIRSF PIRSF000538 7 502 6.1E-175 T 28-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CIG75_RS08935 ab3176cd7791980f9e1aab417584cac0 502 Gene3D G3DSA:3.30.420.40 253 501 6.3E-81 T 28-03-2018 CIG75_RS08935 ab3176cd7791980f9e1aab417584cac0 502 Hamap MF_00186 Glycerol kinase [glpK]. 7 500 57.662 T 28-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 CIG75_RS08935 ab3176cd7791980f9e1aab417584cac0 502 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 9 499 6.1E-224 T 28-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 CIG75_RS08935 ab3176cd7791980f9e1aab417584cac0 502 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 264 453 9.8E-65 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 CIG75_RS08935 ab3176cd7791980f9e1aab417584cac0 502 SUPERFAMILY SSF53067 9 258 1.94E-92 T 28-03-2018 CIG75_RS08935 ab3176cd7791980f9e1aab417584cac0 502 SUPERFAMILY SSF53067 257 499 7.77E-87 T 28-03-2018 CIG75_RS08935 ab3176cd7791980f9e1aab417584cac0 502 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 9 255 7.5E-80 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 CIG75_RS08935 ab3176cd7791980f9e1aab417584cac0 502 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 365 385 - T 28-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CIG75_RS08935 ab3176cd7791980f9e1aab417584cac0 502 Gene3D G3DSA:3.30.420.40 4 252 4.7E-86 T 28-03-2018 CIG75_RS10845 e3d011933466ae2039280a9cfc40b2de 898 Pfam PF05190 MutS family domain IV 425 515 1.5E-30 T 28-03-2018 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 CIG75_RS10845 e3d011933466ae2039280a9cfc40b2de 898 Gene3D G3DSA:3.40.1170.10 1 121 3.4E-45 T 28-03-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 CIG75_RS10845 e3d011933466ae2039280a9cfc40b2de 898 SUPERFAMILY SSF48334 263 560 3.53E-87 T 28-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CIG75_RS10845 e3d011933466ae2039280a9cfc40b2de 898 SMART SM00533 280 588 1.6E-99 T 28-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CIG75_RS10845 e3d011933466ae2039280a9cfc40b2de 898 Pfam PF05192 MutS domain III 266 556 2.5E-41 T 28-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CIG75_RS10845 e3d011933466ae2039280a9cfc40b2de 898 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 1 885 25.176 T 28-03-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 CIG75_RS10845 e3d011933466ae2039280a9cfc40b2de 898 Gene3D G3DSA:1.10.1420.10 259 403 1.4E-35 T 28-03-2018 CIG75_RS10845 e3d011933466ae2039280a9cfc40b2de 898 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 1 807 0.0 T 28-03-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 CIG75_RS10845 e3d011933466ae2039280a9cfc40b2de 898 SUPERFAMILY SSF53150 108 276 1.02E-38 T 28-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 CIG75_RS10845 e3d011933466ae2039280a9cfc40b2de 898 Pfam PF00488 MutS domain V 610 798 7.8E-83 T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CIG75_RS10845 e3d011933466ae2039280a9cfc40b2de 898 Pfam PF01624 MutS domain I 1 110 5.4E-44 T 28-03-2018 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 CIG75_RS10845 e3d011933466ae2039280a9cfc40b2de 898 SUPERFAMILY SSF55271 1 106 6.41E-41 T 28-03-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 CIG75_RS10845 e3d011933466ae2039280a9cfc40b2de 898 Gene3D G3DSA:1.10.1420.10 404 532 1.1E-32 T 28-03-2018 CIG75_RS10845 e3d011933466ae2039280a9cfc40b2de 898 Pfam PF05188 MutS domain II 120 249 1.0E-21 T 28-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 CIG75_RS10845 e3d011933466ae2039280a9cfc40b2de 898 PIRSF PIRSF037677 1 828 2.8E-170 T 28-03-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 CIG75_RS10845 e3d011933466ae2039280a9cfc40b2de 898 SMART SM00534 606 795 2.4E-116 T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CIG75_RS10845 e3d011933466ae2039280a9cfc40b2de 898 SUPERFAMILY SSF52540 564 799 1.64E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS10845 e3d011933466ae2039280a9cfc40b2de 898 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 687 703 - T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CIG75_RS10845 e3d011933466ae2039280a9cfc40b2de 898 Gene3D G3DSA:3.30.420.110 122 258 2.9E-27 T 28-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 CIG75_RS10845 e3d011933466ae2039280a9cfc40b2de 898 Gene3D G3DSA:3.40.50.300 564 817 9.5E-45 T 28-03-2018 CIG75_RS09355 60ec7e44d9542e7e9e5df82dc39b66e0 380 Pfam PF00575 S1 RNA binding domain 268 339 3.6E-22 T 28-03-2018 IPR003029 S1 domain GO:0003676 CIG75_RS09355 60ec7e44d9542e7e9e5df82dc39b66e0 380 Pfam PF00575 S1 RNA binding domain 95 162 5.0E-14 T 28-03-2018 IPR003029 S1 domain GO:0003676 CIG75_RS09355 60ec7e44d9542e7e9e5df82dc39b66e0 380 Pfam PF00575 S1 RNA binding domain 9 81 2.0E-17 T 28-03-2018 IPR003029 S1 domain GO:0003676 CIG75_RS09355 60ec7e44d9542e7e9e5df82dc39b66e0 380 Pfam PF00575 S1 RNA binding domain 182 253 9.8E-25 T 28-03-2018 IPR003029 S1 domain GO:0003676 CIG75_RS09355 60ec7e44d9542e7e9e5df82dc39b66e0 380 SUPERFAMILY SSF50249 84 167 1.86E-15 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CIG75_RS09355 60ec7e44d9542e7e9e5df82dc39b66e0 380 Gene3D G3DSA:2.40.50.140 88 172 1.3E-11 T 28-03-2018 CIG75_RS09355 60ec7e44d9542e7e9e5df82dc39b66e0 380 Gene3D G3DSA:2.40.50.140 1 87 1.1E-21 T 28-03-2018 CIG75_RS09355 60ec7e44d9542e7e9e5df82dc39b66e0 380 Gene3D G3DSA:2.40.50.140 175 258 3.5E-28 T 28-03-2018 CIG75_RS09355 60ec7e44d9542e7e9e5df82dc39b66e0 380 Gene3D G3DSA:2.40.50.140 263 345 4.8E-24 T 28-03-2018 CIG75_RS09355 60ec7e44d9542e7e9e5df82dc39b66e0 380 SMART SM00316 10 81 2.8E-22 T 28-03-2018 IPR022967 RNA-binding domain, S1 CIG75_RS09355 60ec7e44d9542e7e9e5df82dc39b66e0 380 SMART SM00316 268 339 9.0E-25 T 28-03-2018 IPR022967 RNA-binding domain, S1 CIG75_RS09355 60ec7e44d9542e7e9e5df82dc39b66e0 380 SMART SM00316 97 164 5.6E-8 T 28-03-2018 IPR022967 RNA-binding domain, S1 CIG75_RS09355 60ec7e44d9542e7e9e5df82dc39b66e0 380 SMART SM00316 183 253 7.2E-29 T 28-03-2018 IPR022967 RNA-binding domain, S1 CIG75_RS09355 60ec7e44d9542e7e9e5df82dc39b66e0 380 SUPERFAMILY SSF50249 259 341 6.18E-23 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CIG75_RS09355 60ec7e44d9542e7e9e5df82dc39b66e0 380 SUPERFAMILY SSF50249 183 267 1.78E-26 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CIG75_RS09355 60ec7e44d9542e7e9e5df82dc39b66e0 380 PRINTS PR00681 Ribosomal protein S1 signature 322 340 2.1E-51 T 28-03-2018 CIG75_RS09355 60ec7e44d9542e7e9e5df82dc39b66e0 380 PRINTS PR00681 Ribosomal protein S1 signature 148 168 2.1E-51 T 28-03-2018 CIG75_RS09355 60ec7e44d9542e7e9e5df82dc39b66e0 380 PRINTS PR00681 Ribosomal protein S1 signature 205 226 2.1E-51 T 28-03-2018 CIG75_RS09355 60ec7e44d9542e7e9e5df82dc39b66e0 380 PRINTS PR00681 Ribosomal protein S1 signature 119 136 2.1E-51 T 28-03-2018 CIG75_RS09355 60ec7e44d9542e7e9e5df82dc39b66e0 380 PRINTS PR00681 Ribosomal protein S1 signature 12 30 2.1E-51 T 28-03-2018 CIG75_RS09355 60ec7e44d9542e7e9e5df82dc39b66e0 380 PRINTS PR00681 Ribosomal protein S1 signature 102 118 2.1E-51 T 28-03-2018 CIG75_RS09355 60ec7e44d9542e7e9e5df82dc39b66e0 380 PRINTS PR00681 Ribosomal protein S1 signature 78 97 2.1E-51 T 28-03-2018 CIG75_RS09355 60ec7e44d9542e7e9e5df82dc39b66e0 380 PRINTS PR00681 Ribosomal protein S1 signature 30 44 2.1E-51 T 28-03-2018 CIG75_RS09355 60ec7e44d9542e7e9e5df82dc39b66e0 380 PRINTS PR00681 Ribosomal protein S1 signature 283 302 2.1E-51 T 28-03-2018 CIG75_RS09355 60ec7e44d9542e7e9e5df82dc39b66e0 380 SUPERFAMILY SSF50249 8 106 2.13E-24 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CIG75_RS18825 7128f8caf7657566d7080e9f91cb0672 537 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 413 432 - T 28-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CIG75_RS18825 7128f8caf7657566d7080e9f91cb0672 537 SUPERFAMILY SSF52467 153 344 1.71E-31 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CIG75_RS18825 7128f8caf7657566d7080e9f91cb0672 537 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 187 315 1.4E-22 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CIG75_RS18825 7128f8caf7657566d7080e9f91cb0672 537 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 1 163 1.8E-44 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CIG75_RS18825 7128f8caf7657566d7080e9f91cb0672 537 Gene3D G3DSA:3.40.50.1220 192 335 1.9E-28 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CIG75_RS18825 7128f8caf7657566d7080e9f91cb0672 537 Gene3D G3DSA:3.40.50.970 336 527 8.0E-47 T 28-03-2018 CIG75_RS18825 7128f8caf7657566d7080e9f91cb0672 537 Gene3D G3DSA:3.40.50.970 1 191 3.9E-45 T 28-03-2018 CIG75_RS18825 7128f8caf7657566d7080e9f91cb0672 537 SUPERFAMILY SSF52518 1 164 2.06E-41 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CIG75_RS18825 7128f8caf7657566d7080e9f91cb0672 537 SUPERFAMILY SSF52518 353 530 7.33E-58 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CIG75_RS18825 7128f8caf7657566d7080e9f91cb0672 537 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 376 522 1.1E-39 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 Pfam PF00501 AMP-binding enzyme 4222 4625 1.4E-92 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 Pfam PF00501 AMP-binding enzyme 2569 2969 5.2E-103 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 Pfam PF00501 AMP-binding enzyme 471 867 2.6E-110 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 SUPERFAMILY SSF52777 3350 3607 1.0E-60 T 28-03-2018 CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 Gene3D G3DSA:1.10.1200.10 3081 3146 6.2E-19 T 28-03-2018 CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 Pfam PF00550 Phosphopantetheine attachment site 974 1036 1.1E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 Pfam PF00550 Phosphopantetheine attachment site 3650 3713 4.4E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 Pfam PF00550 Phosphopantetheine attachment site 4727 4789 1.3E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 Pfam PF00550 Phosphopantetheine attachment site 2011 2070 4.1E-10 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 Pfam PF00550 Phosphopantetheine attachment site 3078 3140 3.4E-9 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 Gene3D G3DSA:3.40.47.10 1329 1494 3.1E-57 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1442 1553 6.4E-18 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 SUPERFAMILY SSF56801 427 984 3.4E-174 T 28-03-2018 CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 Pfam PF00668 Condensation domain 3764 4202 1.1E-114 T 28-03-2018 IPR001242 Condensation domain CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 Pfam PF00668 Condensation domain 3164 3610 1.9E-115 T 28-03-2018 IPR001242 Condensation domain CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 Pfam PF00668 Condensation domain 2099 2542 1.1E-113 T 28-03-2018 IPR001242 Condensation domain CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 Pfam PF00668 Condensation domain 7 448 6.0E-111 T 28-03-2018 IPR001242 Condensation domain CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 SUPERFAMILY SSF55048 1741 1798 4.19E-7 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 Pfam PF00698 Acyl transferase domain 1590 1893 5.6E-38 T 28-03-2018 IPR014043 Acyl transferase CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 SUPERFAMILY SSF53901 1467 1488 3.59E-81 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 SUPERFAMILY SSF53901 1061 1181 3.59E-81 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 SUPERFAMILY SSF53901 1209 1435 3.59E-81 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 SMART SM00823 Phosphopantetheine attachment site 3648 3717 3.9E-4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 SMART SM00823 Phosphopantetheine attachment site 3075 3144 0.0078 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 SMART SM00823 Phosphopantetheine attachment site 2008 2077 1.4E-4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 SMART SM00823 Phosphopantetheine attachment site 4726 4795 0.22 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 SMART SM00823 Phosphopantetheine attachment site 971 1040 1.8E-7 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 Gene3D G3DSA:3.40.50.980 2560 2713 1.2E-52 T 28-03-2018 CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 Gene3D G3DSA:3.40.50.980 461 617 6.9E-56 T 28-03-2018 CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 SUPERFAMILY SSF47336 2001 2070 9.29E-16 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 Gene3D G3DSA:3.40.47.10 1055 1325 2.2E-66 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 SUPERFAMILY SSF52777 3944 4185 2.56E-65 T 28-03-2018 CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2032 2047 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 SUPERFAMILY SSF56801 2519 3086 8.9E-167 T 28-03-2018 CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 Gene3D G3DSA:3.40.366.10 1587 1750 8.7E-39 T 28-03-2018 CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1321 1440 1.2E-41 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 SUPERFAMILY SSF52151 1803 1894 2.62E-60 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 SUPERFAMILY SSF52151 1588 1641 2.62E-60 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 SUPERFAMILY SSF52151 1670 1743 2.62E-60 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1591 1908 8.4E-100 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4750 4765 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 SUPERFAMILY SSF56801 4178 4739 3.79E-152 T 28-03-2018 CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 Gene3D G3DSA:1.10.1200.10 4732 4798 3.9E-21 T 28-03-2018 CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 Gene3D G3DSA:1.10.1200.10 2002 2074 7.0E-18 T 28-03-2018 CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 SUPERFAMILY SSF47336 3067 3140 6.15E-17 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 Gene3D G3DSA:3.30.300.30 862 974 3.6E-37 T 28-03-2018 CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 Gene3D G3DSA:3.30.300.30 4620 4731 7.4E-35 T 28-03-2018 CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 Gene3D G3DSA:3.30.300.30 2964 3080 3.9E-38 T 28-03-2018 CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 Gene3D G3DSA:3.40.50.980 2714 2880 7.6E-39 T 28-03-2018 CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 Gene3D G3DSA:3.40.50.980 4366 4528 5.3E-28 T 28-03-2018 CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 Gene3D G3DSA:3.40.50.980 618 777 3.4E-40 T 28-03-2018 CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 ProSitePatterns PS00455 Putative AMP-binding domain signature. 612 623 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 Gene3D G3DSA:2.30.38.10 2881 2959 1.9E-21 T 28-03-2018 CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 Gene3D G3DSA:2.30.38.10 4535 4615 3.1E-23 T 28-03-2018 CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 Gene3D G3DSA:2.30.38.10 778 857 3.9E-23 T 28-03-2018 CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2590 2993 5.3E-134 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 4243 4649 3.5E-127 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 492 891 8.4E-143 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 SUPERFAMILY SSF52777 10 186 5.45E-53 T 28-03-2018 CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 Gene3D G3DSA:1.10.1200.10 975 1048 9.6E-23 T 28-03-2018 CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 SUPERFAMILY SSF52777 3166 3344 4.56E-46 T 28-03-2018 CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 SUPERFAMILY SSF52777 2101 2278 8.23E-50 T 28-03-2018 CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 SUPERFAMILY SSF47336 4718 4789 2.36E-18 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 ProSitePatterns PS00455 Putative AMP-binding domain signature. 4361 4372 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 SUPERFAMILY SSF47336 3641 3713 4.97E-19 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 SMART SM00825 Beta-ketoacyl synthase 1065 1492 1.5E-177 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 Gene3D G3DSA:3.40.366.10 1798 1902 1.2E-23 T 28-03-2018 CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 SUPERFAMILY SSF52777 2285 2546 9.34E-65 T 28-03-2018 CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1063 1313 4.4E-68 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2708 2719 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 Gene3D G3DSA:3.30.559.10 5 209 6.8E-47 T 28-03-2018 CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 Gene3D G3DSA:3.30.559.10 3724 3963 2.7E-45 T 28-03-2018 CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 Gene3D G3DSA:3.30.559.10 2075 2302 1.9E-47 T 28-03-2018 CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3672 3687 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 Gene3D G3DSA:3.30.70.250 1751 1797 3.0E-15 T 28-03-2018 CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 Pfam PF13193 AMP-binding enzyme C-terminal domain 4633 4700 5.5E-6 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 Pfam PF13193 AMP-binding enzyme C-terminal domain 875 943 2.4E-11 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 Pfam PF13193 AMP-binding enzyme C-terminal domain 2977 3047 9.7E-12 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 SUPERFAMILY SSF47336 963 1037 2.09E-20 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 Gene3D G3DSA:1.10.1200.10 3625 3723 2.9E-23 T 28-03-2018 CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 Gene3D G3DSA:3.30.559.10 3147 3362 1.3E-34 T 28-03-2018 CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 Gene3D G3DSA:3.40.50.980 4215 4365 2.8E-47 T 28-03-2018 CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 SUPERFAMILY SSF52777 194 433 4.78E-61 T 28-03-2018 CIG75_RS07015 c9f40f38a492b186dca6068f8628b11c 4816 SUPERFAMILY SSF52777 3766 3937 2.89E-50 T 28-03-2018 CIG75_RS03675 6244afa238b99ab77e036c8469f16df4 392 Pfam PF13671 AAA domain 16 145 5.4E-14 T 28-03-2018 CIG75_RS03675 6244afa238b99ab77e036c8469f16df4 392 SUPERFAMILY SSF52540 13 142 1.09E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS03675 6244afa238b99ab77e036c8469f16df4 392 Gene3D G3DSA:3.40.50.300 13 146 3.4E-17 T 28-03-2018 CIG75_RS03675 6244afa238b99ab77e036c8469f16df4 392 SUPERFAMILY SSF109604 192 255 1.98E-12 T 28-03-2018 CIG75_RS03675 6244afa238b99ab77e036c8469f16df4 392 SUPERFAMILY SSF109604 312 355 1.98E-12 T 28-03-2018 CIG75_RS03675 6244afa238b99ab77e036c8469f16df4 392 Gene3D G3DSA:1.10.3090.10 147 392 3.4E-17 T 28-03-2018 CIG75_RS13865 e9b6a3b7c1d2e516033854a73495103a 298 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 217 229 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site CIG75_RS13865 e9b6a3b7c1d2e516033854a73495103a 298 Pfam PF00348 Polyprenyl synthetase 35 268 1.2E-61 T 28-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 CIG75_RS13865 e9b6a3b7c1d2e516033854a73495103a 298 Gene3D G3DSA:1.10.600.10 1 298 1.9E-92 T 28-03-2018 IPR008949 Isoprenoid synthase domain CIG75_RS13865 e9b6a3b7c1d2e516033854a73495103a 298 SUPERFAMILY SSF48576 6 289 1.78E-88 T 28-03-2018 IPR008949 Isoprenoid synthase domain CIG75_RS13865 e9b6a3b7c1d2e516033854a73495103a 298 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 85 101 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site CIG75_RS16270 faee6a4859aa029d12b43ae0bc89bfbc 165 SUPERFAMILY SSF88946 10 95 4.51E-21 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS16270 faee6a4859aa029d12b43ae0bc89bfbc 165 Pfam PF08281 Sigma-70, region 4 109 161 5.6E-14 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS16270 faee6a4859aa029d12b43ae0bc89bfbc 165 SUPERFAMILY SSF88659 104 165 2.24E-12 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS16270 faee6a4859aa029d12b43ae0bc89bfbc 165 Pfam PF04542 Sigma-70 region 2 19 84 2.7E-15 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS16270 faee6a4859aa029d12b43ae0bc89bfbc 165 Gene3D G3DSA:1.10.10.10 93 165 8.5E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS16270 faee6a4859aa029d12b43ae0bc89bfbc 165 Gene3D G3DSA:1.10.1740.10 2 86 4.9E-20 T 28-03-2018 CIG75_RS16270 faee6a4859aa029d12b43ae0bc89bfbc 165 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 14 164 2.6E-28 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS00485 9908d207ab5b1e7986bcd4bdd8e816b3 391 Pfam PF07687 Peptidase dimerisation domain 188 270 1.2E-12 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CIG75_RS00485 9908d207ab5b1e7986bcd4bdd8e816b3 391 Gene3D G3DSA:3.40.630.10 252 391 1.4E-30 T 28-03-2018 CIG75_RS00485 9908d207ab5b1e7986bcd4bdd8e816b3 391 Gene3D G3DSA:3.40.630.10 2 245 1.1E-46 T 28-03-2018 CIG75_RS00485 9908d207ab5b1e7986bcd4bdd8e816b3 391 SUPERFAMILY SSF53187 301 390 1.57E-85 T 28-03-2018 CIG75_RS00485 9908d207ab5b1e7986bcd4bdd8e816b3 391 SUPERFAMILY SSF53187 6 200 1.57E-85 T 28-03-2018 CIG75_RS00485 9908d207ab5b1e7986bcd4bdd8e816b3 391 SUPERFAMILY SSF55031 184 301 2.75E-33 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CIG75_RS00485 9908d207ab5b1e7986bcd4bdd8e816b3 391 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 18 377 5.1E-119 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CIG75_RS00485 9908d207ab5b1e7986bcd4bdd8e816b3 391 PIRSF PIRSF005962 2 391 1.2E-136 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CIG75_RS00485 9908d207ab5b1e7986bcd4bdd8e816b3 391 Pfam PF01546 Peptidase family M20/M25/M40 75 385 1.6E-37 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CIG75_RS13745 812c8a158f1ecdad6f0415c05eabf947 67 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 23 32 - T 28-03-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 CIG75_RS13745 812c8a158f1ecdad6f0415c05eabf947 67 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 8 62 4.2E-21 T 28-03-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 CIG75_RS20125 f673d0ec030876677382f371c6030ab6 398 Hamap MF_01113 DNA polymerase IV [dinB]. 2 355 39.069 T 28-03-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 CIG75_RS20125 f673d0ec030876677382f371c6030ab6 398 SUPERFAMILY SSF56672 2 235 2.67E-85 T 28-03-2018 CIG75_RS20125 f673d0ec030876677382f371c6030ab6 398 Pfam PF11799 impB/mucB/samB family C-terminal domain 234 348 1.7E-23 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CIG75_RS20125 f673d0ec030876677382f371c6030ab6 398 Gene3D G3DSA:3.30.70.270 115 171 1.3E-15 T 28-03-2018 CIG75_RS20125 f673d0ec030876677382f371c6030ab6 398 Gene3D G3DSA:3.30.70.270 42 114 4.8E-26 T 28-03-2018 CIG75_RS20125 f673d0ec030876677382f371c6030ab6 398 Gene3D G3DSA:1.10.150.20 172 242 7.9E-19 T 28-03-2018 CIG75_RS20125 f673d0ec030876677382f371c6030ab6 398 Pfam PF00817 impB/mucB/samB family 8 154 2.9E-52 T 28-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CIG75_RS20125 f673d0ec030876677382f371c6030ab6 398 SUPERFAMILY SSF100879 239 340 4.12E-28 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CIG75_RS20125 f673d0ec030876677382f371c6030ab6 398 Gene3D G3DSA:3.30.1490.100 243 357 1.4E-28 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CIG75_RS14670 22b51ff88697ac23cdae9da85b470d04 210 Pfam PF00571 CBS domain 82 127 1.0E-7 T 28-03-2018 IPR000644 CBS domain CIG75_RS14670 22b51ff88697ac23cdae9da85b470d04 210 Pfam PF00571 CBS domain 143 200 3.8E-8 T 28-03-2018 IPR000644 CBS domain CIG75_RS14670 22b51ff88697ac23cdae9da85b470d04 210 SUPERFAMILY SSF54631 68 203 1.46E-21 T 28-03-2018 CIG75_RS14670 22b51ff88697ac23cdae9da85b470d04 210 Gene3D G3DSA:3.10.580.10 59 209 3.5E-25 T 28-03-2018 CIG75_RS14670 22b51ff88697ac23cdae9da85b470d04 210 SMART SM00116 81 129 9.4E-5 T 28-03-2018 IPR000644 CBS domain CIG75_RS14670 22b51ff88697ac23cdae9da85b470d04 210 SMART SM00116 148 202 0.19 T 28-03-2018 IPR000644 CBS domain CIG75_RS14670 22b51ff88697ac23cdae9da85b470d04 210 SUPERFAMILY SSF46785 1 76 1.56E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS14670 22b51ff88697ac23cdae9da85b470d04 210 Gene3D G3DSA:1.10.10.10 1 58 1.2E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS14670 22b51ff88697ac23cdae9da85b470d04 210 PIRSF PIRSF026546 1 208 2.4E-93 T 28-03-2018 IPR016842 Protein of unknown function UCP026546, HtH-CBS CIG75_RS14670 22b51ff88697ac23cdae9da85b470d04 210 Pfam PF08279 HTH domain 4 56 4.6E-12 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 CIG75_RS09670 92619dd8e2d6dc750bc6aea198c29f5c 318 Gene3D G3DSA:3.40.1090.10 15 286 1.1E-43 T 28-03-2018 CIG75_RS09670 92619dd8e2d6dc750bc6aea198c29f5c 318 Pfam PF01734 Patatin-like phospholipase 25 224 3.9E-29 T 28-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 CIG75_RS09670 92619dd8e2d6dc750bc6aea198c29f5c 318 SUPERFAMILY SSF52151 21 311 4.71E-49 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CIG75_RS07375 36cf26ea83ff884bbc72b447ca612e15 620 Pfam PF00664 ABC transporter transmembrane region 39 311 7.8E-56 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CIG75_RS07375 36cf26ea83ff884bbc72b447ca612e15 620 ProSitePatterns PS00211 ABC transporters family signature. 494 508 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS07375 36cf26ea83ff884bbc72b447ca612e15 620 SMART SM00382 382 570 6.9E-19 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS07375 36cf26ea83ff884bbc72b447ca612e15 620 SUPERFAMILY SSF52540 346 595 1.0E-91 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS07375 36cf26ea83ff884bbc72b447ca612e15 620 SUPERFAMILY SSF90123 20 343 7.46E-82 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CIG75_RS07375 36cf26ea83ff884bbc72b447ca612e15 620 Pfam PF00005 ABC transporter 374 522 4.4E-37 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS07375 36cf26ea83ff884bbc72b447ca612e15 620 Gene3D G3DSA:3.40.50.300 343 600 5.3E-80 T 28-03-2018 CIG75_RS07375 36cf26ea83ff884bbc72b447ca612e15 620 Gene3D G3DSA:1.20.1560.10 10 342 1.5E-74 T 28-03-2018 CIG75_RS10680 9eddc3f8b06eff029e2366def37706c9 592 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 414 441 9.5E-23 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CIG75_RS10680 9eddc3f8b06eff029e2366def37706c9 592 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 443 472 9.5E-23 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CIG75_RS10680 9eddc3f8b06eff029e2366def37706c9 592 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 31 56 9.5E-23 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CIG75_RS10680 9eddc3f8b06eff029e2366def37706c9 592 SMART SM00304 233 287 7.1E-14 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CIG75_RS10680 9eddc3f8b06eff029e2366def37706c9 592 SMART SM00283 316 591 2.0E-85 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CIG75_RS10680 9eddc3f8b06eff029e2366def37706c9 592 Gene3D G3DSA:1.10.287.950 541 592 2.7E-8 T 28-03-2018 CIG75_RS10680 9eddc3f8b06eff029e2366def37706c9 592 Gene3D G3DSA:1.10.287.950 348 540 2.2E-51 T 28-03-2018 CIG75_RS10680 9eddc3f8b06eff029e2366def37706c9 592 Gene3D G3DSA:1.10.287.950 105 347 9.8E-7 T 28-03-2018 CIG75_RS10680 9eddc3f8b06eff029e2366def37706c9 592 Pfam PF00672 HAMP domain 233 283 3.5E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CIG75_RS10680 9eddc3f8b06eff029e2366def37706c9 592 SUPERFAMILY SSF58104 322 590 3.79E-74 T 28-03-2018 CIG75_RS10680 9eddc3f8b06eff029e2366def37706c9 592 SUPERFAMILY SSF58104 255 289 3.79E-74 T 28-03-2018 CIG75_RS10680 9eddc3f8b06eff029e2366def37706c9 592 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 360 545 1.9E-45 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CIG75_RS01190 e3b550a1b13a4696a60f987197960388 275 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 125 142 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CIG75_RS01190 e3b550a1b13a4696a60f987197960388 275 Pfam PF00248 Aldo/keto reductase family 28 261 7.8E-52 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CIG75_RS01190 e3b550a1b13a4696a60f987197960388 275 PIRSF PIRSF000097 2 273 1.3E-86 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CIG75_RS01190 e3b550a1b13a4696a60f987197960388 275 SUPERFAMILY SSF51430 9 267 5.37E-96 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CIG75_RS01190 e3b550a1b13a4696a60f987197960388 275 Gene3D G3DSA:3.20.20.100 2 275 1.8E-101 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CIG75_RS01190 e3b550a1b13a4696a60f987197960388 275 PRINTS PR00069 Aldo-keto reductase signature 95 113 1.2E-50 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CIG75_RS01190 e3b550a1b13a4696a60f987197960388 275 PRINTS PR00069 Aldo-keto reductase signature 196 220 1.2E-50 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CIG75_RS01190 e3b550a1b13a4696a60f987197960388 275 PRINTS PR00069 Aldo-keto reductase signature 125 142 1.2E-50 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CIG75_RS01190 e3b550a1b13a4696a60f987197960388 275 PRINTS PR00069 Aldo-keto reductase signature 39 63 1.2E-50 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CIG75_RS01190 e3b550a1b13a4696a60f987197960388 275 PRINTS PR00069 Aldo-keto reductase signature 159 188 1.2E-50 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CIG75_RS01190 e3b550a1b13a4696a60f987197960388 275 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 43 60 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CIG75_RS04335 bbf582327ad10318a5779f5e1c4d7b6b 381 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 170 180 - T 28-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site CIG75_RS04335 bbf582327ad10318a5779f5e1c4d7b6b 381 Gene3D G3DSA:3.40.50.200 85 381 7.7E-93 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CIG75_RS04335 bbf582327ad10318a5779f5e1c4d7b6b 381 SUPERFAMILY SSF52743 110 381 4.06E-87 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CIG75_RS04335 bbf582327ad10318a5779f5e1c4d7b6b 381 Pfam PF00082 Subtilase family 130 361 3.4E-47 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CIG75_RS04335 bbf582327ad10318a5779f5e1c4d7b6b 381 Gene3D G3DSA:3.30.70.80 29 84 1.9E-5 T 28-03-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 CIG75_RS04335 bbf582327ad10318a5779f5e1c4d7b6b 381 PRINTS PR00723 Subtilisin serine protease family (S8) signature 166 179 2.2E-19 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CIG75_RS04335 bbf582327ad10318a5779f5e1c4d7b6b 381 PRINTS PR00723 Subtilisin serine protease family (S8) signature 128 147 2.2E-19 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CIG75_RS04335 bbf582327ad10318a5779f5e1c4d7b6b 381 PRINTS PR00723 Subtilisin serine protease family (S8) signature 321 337 2.2E-19 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CIG75_RS04335 bbf582327ad10318a5779f5e1c4d7b6b 381 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 133 144 - T 28-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site CIG75_RS04335 bbf582327ad10318a5779f5e1c4d7b6b 381 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 322 332 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CIG75_RS15435 47b7b60511a6d0ee56242a571ae1b46c 387 Pfam PF07690 Major Facilitator Superfamily 3 253 1.5E-33 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CIG75_RS15435 47b7b60511a6d0ee56242a571ae1b46c 387 SUPERFAMILY SSF103473 243 385 2.75E-31 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS15435 47b7b60511a6d0ee56242a571ae1b46c 387 PRINTS PR01035 Tetracycline resistance protein signature 38 57 1.1E-9 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CIG75_RS15435 47b7b60511a6d0ee56242a571ae1b46c 387 PRINTS PR01035 Tetracycline resistance protein signature 69 93 1.1E-9 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CIG75_RS15435 47b7b60511a6d0ee56242a571ae1b46c 387 PRINTS PR01035 Tetracycline resistance protein signature 96 117 1.1E-9 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CIG75_RS15435 47b7b60511a6d0ee56242a571ae1b46c 387 PRINTS PR01035 Tetracycline resistance protein signature 126 148 1.1E-9 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CIG75_RS15435 47b7b60511a6d0ee56242a571ae1b46c 387 PRINTS PR01035 Tetracycline resistance protein signature 244 264 1.1E-9 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CIG75_RS15435 47b7b60511a6d0ee56242a571ae1b46c 387 PRINTS PR01035 Tetracycline resistance protein signature 332 355 1.1E-9 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CIG75_RS15435 47b7b60511a6d0ee56242a571ae1b46c 387 SUPERFAMILY SSF103473 3 237 7.46E-43 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS15435 47b7b60511a6d0ee56242a571ae1b46c 387 Gene3D G3DSA:1.20.1250.20 1 190 6.3E-35 T 28-03-2018 CIG75_RS15435 47b7b60511a6d0ee56242a571ae1b46c 387 Gene3D G3DSA:1.20.1250.20 194 385 9.1E-34 T 28-03-2018 CIG75_RS06230 486f84de1a6b9696fa9bc471ae2d212c 565 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 17 42 2.4E-12 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CIG75_RS06230 486f84de1a6b9696fa9bc471ae2d212c 565 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 414 443 2.4E-12 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CIG75_RS06230 486f84de1a6b9696fa9bc471ae2d212c 565 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 385 412 2.4E-12 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CIG75_RS06230 486f84de1a6b9696fa9bc471ae2d212c 565 Gene3D G3DSA:1.10.287.950 315 565 1.7E-43 T 28-03-2018 CIG75_RS06230 486f84de1a6b9696fa9bc471ae2d212c 565 Gene3D G3DSA:1.10.287.950 226 314 3.2E-4 T 28-03-2018 CIG75_RS06230 486f84de1a6b9696fa9bc471ae2d212c 565 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 333 515 5.5E-33 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CIG75_RS06230 486f84de1a6b9696fa9bc471ae2d212c 565 SMART SM00283 287 562 5.1E-50 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CIG75_RS06230 486f84de1a6b9696fa9bc471ae2d212c 565 Pfam PF00672 HAMP domain 206 254 1.2E-13 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CIG75_RS06230 486f84de1a6b9696fa9bc471ae2d212c 565 SMART SM00304 206 258 1.7E-14 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CIG75_RS06230 486f84de1a6b9696fa9bc471ae2d212c 565 SUPERFAMILY SSF58104 226 260 7.72E-58 T 28-03-2018 CIG75_RS06230 486f84de1a6b9696fa9bc471ae2d212c 565 SUPERFAMILY SSF58104 293 562 7.72E-58 T 28-03-2018 CIG75_RS11985 aada2112efb0bc841479064295d45998 254 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 182 202 2.1E-66 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CIG75_RS11985 aada2112efb0bc841479064295d45998 254 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 227 252 2.1E-66 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CIG75_RS11985 aada2112efb0bc841479064295d45998 254 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 55 74 2.1E-66 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CIG75_RS11985 aada2112efb0bc841479064295d45998 254 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 74 94 2.1E-66 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CIG75_RS11985 aada2112efb0bc841479064295d45998 254 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 94 113 2.1E-66 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CIG75_RS11985 aada2112efb0bc841479064295d45998 254 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 203 224 2.1E-66 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CIG75_RS11985 aada2112efb0bc841479064295d45998 254 TIGRFAM TIGR01103 fliP: flagellar biosynthetic protein FliP 57 250 3.7E-87 T 28-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CIG75_RS11985 aada2112efb0bc841479064295d45998 254 Pfam PF00813 FliP family 57 249 3.0E-83 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CIG75_RS11985 aada2112efb0bc841479064295d45998 254 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 175 187 4.3E-18 T 28-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CIG75_RS11985 aada2112efb0bc841479064295d45998 254 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 153 165 4.3E-18 T 28-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CIG75_RS11985 aada2112efb0bc841479064295d45998 254 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 243 253 4.3E-18 T 28-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CIG75_RS11985 aada2112efb0bc841479064295d45998 254 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 53 62 4.3E-18 T 28-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CIG75_RS11985 aada2112efb0bc841479064295d45998 254 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 113 125 4.3E-18 T 28-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CIG75_RS11985 aada2112efb0bc841479064295d45998 254 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 125 139 4.3E-18 T 28-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CIG75_RS11985 aada2112efb0bc841479064295d45998 254 ProSitePatterns PS01060 Flagella transport protein fliP family signature 1. 182 197 - T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CIG75_RS11985 aada2112efb0bc841479064295d45998 254 ProSitePatterns PS01061 Flagella transport protein fliP family signature 2. 230 242 - T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CIG75_RS03735 614bc0f5b5502f68ab9a929c8248faa9 525 SMART SM00283 251 512 2.2E-46 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CIG75_RS03735 614bc0f5b5502f68ab9a929c8248faa9 525 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 218 506 0.004 T 28-03-2018 CIG75_RS03735 614bc0f5b5502f68ab9a929c8248faa9 525 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 324 480 1.6E-34 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CIG75_RS03735 614bc0f5b5502f68ab9a929c8248faa9 525 Gene3D G3DSA:1.10.287.950 277 524 3.1E-45 T 28-03-2018 CIG75_RS03735 614bc0f5b5502f68ab9a929c8248faa9 525 Gene3D G3DSA:1.10.287.950 187 276 0.016 T 28-03-2018 CIG75_RS03735 614bc0f5b5502f68ab9a929c8248faa9 525 SUPERFAMILY SSF58104 257 521 5.76E-55 T 28-03-2018 CIG75_RS07690 c65701a086715409405b11f99d37fab4 514 PIRSF PIRSF005690 32 514 9.3E-127 T 28-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 CIG75_RS07690 c65701a086715409405b11f99d37fab4 514 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 53 504 3.4E-151 T 28-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 CIG75_RS05110 7135bc4014e77dc62784541b4250723d 1549 SUPERFAMILY SSF117074 1356 1434 2.35E-17 T 28-03-2018 CIG75_RS05110 7135bc4014e77dc62784541b4250723d 1549 SUPERFAMILY SSF117074 871 959 8.63E-15 T 28-03-2018 CIG75_RS05110 7135bc4014e77dc62784541b4250723d 1549 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 1517 1547 3.4E-5 T 28-03-2018 CIG75_RS05110 7135bc4014e77dc62784541b4250723d 1549 SUPERFAMILY SSF117074 1199 1329 1.83E-17 T 28-03-2018 CIG75_RS05110 7135bc4014e77dc62784541b4250723d 1549 Pfam PF17210 SdrD B-like domain 1231 1346 5.4E-27 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CIG75_RS05110 7135bc4014e77dc62784541b4250723d 1549 Pfam PF17210 SdrD B-like domain 874 955 8.4E-18 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CIG75_RS05110 7135bc4014e77dc62784541b4250723d 1549 Pfam PF17210 SdrD B-like domain 1107 1218 3.5E-28 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CIG75_RS05110 7135bc4014e77dc62784541b4250723d 1549 Pfam PF17210 SdrD B-like domain 984 1100 2.2E-26 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CIG75_RS05110 7135bc4014e77dc62784541b4250723d 1549 Pfam PF17210 SdrD B-like domain 1357 1464 4.9E-24 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CIG75_RS05110 7135bc4014e77dc62784541b4250723d 1549 SUPERFAMILY SSF117074 1098 1184 5.49E-18 T 28-03-2018 CIG75_RS05110 7135bc4014e77dc62784541b4250723d 1549 Gene3D G3DSA:2.60.40.740 311 478 0.37 T 28-03-2018 CIG75_RS05110 7135bc4014e77dc62784541b4250723d 1549 Gene3D G3DSA:2.60.40.740 479 632 2.1E-14 T 28-03-2018 CIG75_RS05110 7135bc4014e77dc62784541b4250723d 1549 SUPERFAMILY SSF117074 970 1074 6.28E-17 T 28-03-2018 CIG75_RS05110 7135bc4014e77dc62784541b4250723d 1549 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 496 547 3.0E-7 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CIG75_RS05110 7135bc4014e77dc62784541b4250723d 1549 Gene3D G3DSA:2.60.40.1220 195 283 1.5E-7 T 28-03-2018 CIG75_RS05110 7135bc4014e77dc62784541b4250723d 1549 Pfam PF01345 Domain of unknown function DUF11 496 553 2.1E-7 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CIG75_RS05110 7135bc4014e77dc62784541b4250723d 1549 Gene3D G3DSA:2.60.40.740 41 177 8.8E-7 T 28-03-2018 CIG75_RS05110 7135bc4014e77dc62784541b4250723d 1549 Gene3D G3DSA:2.60.40.10 1353 1484 8.2E-24 T 28-03-2018 IPR013783 Immunoglobulin-like fold CIG75_RS05110 7135bc4014e77dc62784541b4250723d 1549 Gene3D G3DSA:2.60.40.10 1104 1222 8.2E-18 T 28-03-2018 IPR013783 Immunoglobulin-like fold CIG75_RS05110 7135bc4014e77dc62784541b4250723d 1549 Gene3D G3DSA:2.60.40.10 871 975 2.8E-18 T 28-03-2018 IPR013783 Immunoglobulin-like fold CIG75_RS05110 7135bc4014e77dc62784541b4250723d 1549 Gene3D G3DSA:2.60.40.10 979 1103 1.1E-21 T 28-03-2018 IPR013783 Immunoglobulin-like fold CIG75_RS05110 7135bc4014e77dc62784541b4250723d 1549 Gene3D G3DSA:2.60.40.10 1227 1352 5.0E-20 T 28-03-2018 IPR013783 Immunoglobulin-like fold CIG75_RS16990 a0765d8593ef84c854c5ae6c2b27d880 66 Gene3D G3DSA:2.40.50.140 1 66 1.4E-27 T 28-03-2018 CIG75_RS16990 a0765d8593ef84c854c5ae6c2b27d880 66 PRINTS PR00050 Cold shock protein signature 4 19 4.1E-19 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CIG75_RS16990 a0765d8593ef84c854c5ae6c2b27d880 66 PRINTS PR00050 Cold shock protein signature 39 57 4.1E-19 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CIG75_RS16990 a0765d8593ef84c854c5ae6c2b27d880 66 PRINTS PR00050 Cold shock protein signature 24 33 4.1E-19 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CIG75_RS16990 a0765d8593ef84c854c5ae6c2b27d880 66 SUPERFAMILY SSF50249 1 65 4.08E-25 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CIG75_RS16990 a0765d8593ef84c854c5ae6c2b27d880 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 28-03-2018 IPR019844 Cold-shock conserved site CIG75_RS16990 a0765d8593ef84c854c5ae6c2b27d880 66 SMART SM00357 3 66 5.5E-31 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 CIG75_RS16990 a0765d8593ef84c854c5ae6c2b27d880 66 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 1.4E-30 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CIG75_RS16990 a0765d8593ef84c854c5ae6c2b27d880 66 PIRSF PIRSF002599 1 66 4.7E-24 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 CIG75_RS03460 4036c2cc861ce0874d2abc9626160973 244 Pfam PF00005 ABC transporter 19 161 1.8E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS03460 4036c2cc861ce0874d2abc9626160973 244 SMART SM00382 27 211 1.8E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS03460 4036c2cc861ce0874d2abc9626160973 244 SUPERFAMILY SSF52540 2 225 7.88E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS03460 4036c2cc861ce0874d2abc9626160973 244 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS03460 4036c2cc861ce0874d2abc9626160973 244 Gene3D G3DSA:3.40.50.300 1 236 2.8E-59 T 28-03-2018 CIG75_RS00055 36f23a4c443fb1902d676817de41772b 88 TIGRFAM TIGR02862 spore_BofA: pro-sigmaK processing inhibitor BofA 6 86 3.9E-18 T 28-03-2018 IPR010001 SigmaK-factor processing regulatory BofA CIG75_RS00055 36f23a4c443fb1902d676817de41772b 88 Pfam PF07441 SigmaK-factor processing regulatory protein BofA 14 86 3.0E-19 T 28-03-2018 IPR010001 SigmaK-factor processing regulatory BofA CIG75_RS12365 19c5dee911481433c5e7aa3b6e859684 317 Gene3D G3DSA:3.30.70.250 143 187 1.4E-18 T 28-03-2018 CIG75_RS12365 19c5dee911481433c5e7aa3b6e859684 317 Pfam PF00698 Acyl transferase domain 6 286 5.0E-46 T 28-03-2018 IPR014043 Acyl transferase CIG75_RS12365 19c5dee911481433c5e7aa3b6e859684 317 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 7 313 5.5E-56 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CIG75_RS12365 19c5dee911481433c5e7aa3b6e859684 317 Gene3D G3DSA:3.40.366.10 188 312 3.1E-28 T 28-03-2018 CIG75_RS12365 19c5dee911481433c5e7aa3b6e859684 317 SUPERFAMILY SSF52151 189 308 1.65E-79 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CIG75_RS12365 19c5dee911481433c5e7aa3b6e859684 317 SUPERFAMILY SSF52151 4 121 1.65E-79 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CIG75_RS12365 19c5dee911481433c5e7aa3b6e859684 317 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 3 291 9.1E-108 T 28-03-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 CIG75_RS12365 19c5dee911481433c5e7aa3b6e859684 317 SUPERFAMILY SSF55048 129 192 4.71E-14 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CIG75_RS12365 19c5dee911481433c5e7aa3b6e859684 317 Gene3D G3DSA:3.40.366.10 3 142 3.0E-45 T 28-03-2018 CIG75_RS12365 19c5dee911481433c5e7aa3b6e859684 317 PIRSF PIRSF000446 1 311 5.1E-110 T 28-03-2018 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 CIG75_RS06885 3cc1274ad8eda4678cb6d86028e28801 345 Gene3D G3DSA:3.90.1150.10 248 343 1.5E-32 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CIG75_RS06885 3cc1274ad8eda4678cb6d86028e28801 345 SUPERFAMILY SSF53383 2 342 1.18E-120 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CIG75_RS06885 3cc1274ad8eda4678cb6d86028e28801 345 PIRSF PIRSF017617 1 345 2.3E-136 T 28-03-2018 IPR023603 Threonine aldolase CIG75_RS06885 3cc1274ad8eda4678cb6d86028e28801 345 Pfam PF01212 Beta-eliminating lyase 4 287 6.0E-93 T 28-03-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 CIG75_RS06885 3cc1274ad8eda4678cb6d86028e28801 345 Gene3D G3DSA:3.40.640.10 1 247 9.5E-49 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CIG75_RS10030 143ceabac21620db416237b056cb286b 238 SUPERFAMILY SSF55811 71 221 3.38E-25 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CIG75_RS10030 143ceabac21620db416237b056cb286b 238 Pfam PF00293 NUDIX domain 74 217 1.4E-14 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CIG75_RS10030 143ceabac21620db416237b056cb286b 238 ProSitePatterns PS00893 Nudix box signature. 109 130 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CIG75_RS10030 143ceabac21620db416237b056cb286b 238 Gene3D G3DSA:3.90.79.10 73 228 2.6E-22 T 28-03-2018 CIG75_RS06660 0fc60bf21599085dfe31868917eeb6c2 1126 SUPERFAMILY SSF56801 472 1034 2.22E-161 T 28-03-2018 CIG75_RS06660 0fc60bf21599085dfe31868917eeb6c2 1126 Gene3D G3DSA:3.40.50.980 662 821 1.5E-34 T 28-03-2018 CIG75_RS06660 0fc60bf21599085dfe31868917eeb6c2 1126 Pfam PF00501 AMP-binding enzyme 514 913 9.3E-101 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS06660 0fc60bf21599085dfe31868917eeb6c2 1126 ProSitePatterns PS00455 Putative AMP-binding domain signature. 656 667 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS06660 0fc60bf21599085dfe31868917eeb6c2 1126 SUPERFAMILY SSF52777 55 229 1.11E-45 T 28-03-2018 CIG75_RS06660 0fc60bf21599085dfe31868917eeb6c2 1126 Gene3D G3DSA:2.30.38.10 822 902 2.4E-24 T 28-03-2018 CIG75_RS06660 0fc60bf21599085dfe31868917eeb6c2 1126 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 535 937 1.7E-133 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS06660 0fc60bf21599085dfe31868917eeb6c2 1126 SUPERFAMILY SSF52777 240 500 1.33E-56 T 28-03-2018 CIG75_RS06660 0fc60bf21599085dfe31868917eeb6c2 1126 SMART SM00823 Phosphopantetheine attachment site 1021 1090 0.0016 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS06660 0fc60bf21599085dfe31868917eeb6c2 1126 Gene3D G3DSA:3.30.559.10 27 253 2.3E-36 T 28-03-2018 CIG75_RS06660 0fc60bf21599085dfe31868917eeb6c2 1126 Pfam PF00550 Phosphopantetheine attachment site 1023 1086 8.8E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS06660 0fc60bf21599085dfe31868917eeb6c2 1126 Pfam PF00668 Condensation domain 51 493 4.8E-103 T 28-03-2018 IPR001242 Condensation domain CIG75_RS06660 0fc60bf21599085dfe31868917eeb6c2 1126 Gene3D G3DSA:3.40.50.980 505 661 2.5E-49 T 28-03-2018 CIG75_RS06660 0fc60bf21599085dfe31868917eeb6c2 1126 PIRSF PIRSF001617 957 1122 2.2E-19 T 28-03-2018 CIG75_RS06660 0fc60bf21599085dfe31868917eeb6c2 1126 PIRSF PIRSF001617 878 962 2.0E-17 T 28-03-2018 CIG75_RS06660 0fc60bf21599085dfe31868917eeb6c2 1126 PIRSF PIRSF001617 649 883 1.7E-20 T 28-03-2018 CIG75_RS06660 0fc60bf21599085dfe31868917eeb6c2 1126 PIRSF PIRSF001617 237 622 8.5E-26 T 28-03-2018 CIG75_RS06660 0fc60bf21599085dfe31868917eeb6c2 1126 Gene3D G3DSA:3.30.300.30 908 1024 7.2E-37 T 28-03-2018 CIG75_RS06660 0fc60bf21599085dfe31868917eeb6c2 1126 Pfam PF13193 AMP-binding enzyme C-terminal domain 921 993 3.6E-11 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS06660 0fc60bf21599085dfe31868917eeb6c2 1126 SUPERFAMILY SSF47336 1013 1087 2.09E-20 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS06660 0fc60bf21599085dfe31868917eeb6c2 1126 Gene3D G3DSA:1.10.1200.10 1025 1099 9.8E-22 T 28-03-2018 CIG75_RS04560 71e8288a69dfa5617d58047d34092e09 269 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 163 266 2.6E-28 T 28-03-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 CIG75_RS04560 71e8288a69dfa5617d58047d34092e09 269 Gene3D G3DSA:3.40.50.720 1 165 1.1E-23 T 28-03-2018 CIG75_RS04560 71e8288a69dfa5617d58047d34092e09 269 SUPERFAMILY SSF51735 5 158 7.63E-29 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS04560 71e8288a69dfa5617d58047d34092e09 269 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 4 266 22.135 T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CIG75_RS04560 71e8288a69dfa5617d58047d34092e09 269 PIRSF PIRSF000193 3 269 1.1E-64 T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CIG75_RS04560 71e8288a69dfa5617d58047d34092e09 269 Gene3D G3DSA:1.10.3730.10 166 269 1.7E-30 T 28-03-2018 CIG75_RS04560 71e8288a69dfa5617d58047d34092e09 269 SUPERFAMILY SSF48179 163 268 9.52E-28 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CIG75_RS04560 71e8288a69dfa5617d58047d34092e09 269 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 222 244 - T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CIG75_RS04560 71e8288a69dfa5617d58047d34092e09 269 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 6 266 3.9E-68 T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CIG75_RS04560 71e8288a69dfa5617d58047d34092e09 269 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 6 100 3.6E-16 T 28-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal CIG75_RS01245 3746cab94520778ae562f09831189b24 236 SUPERFAMILY SSF47090 26 100 1.33E-17 T 28-03-2018 IPR002477 Peptidoglycan binding-like CIG75_RS01245 3746cab94520778ae562f09831189b24 236 SUPERFAMILY SSF55166 110 223 1.45E-28 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CIG75_RS01245 3746cab94520778ae562f09831189b24 236 Pfam PF08291 Peptidase M15 110 220 2.3E-24 T 28-03-2018 IPR013230 Peptidase M15A, C-terminal KEGG: 00550+3.4.17.14|MetaCyc: PWY-6470 CIG75_RS01245 3746cab94520778ae562f09831189b24 236 Gene3D G3DSA:1.10.101.10 23 108 5.7E-20 T 28-03-2018 IPR002477 Peptidoglycan binding-like CIG75_RS01245 3746cab94520778ae562f09831189b24 236 Pfam PF01471 Putative peptidoglycan binding domain 38 98 5.1E-14 T 28-03-2018 IPR002477 Peptidoglycan binding-like CIG75_RS01245 3746cab94520778ae562f09831189b24 236 Gene3D G3DSA:3.30.1380.10 110 232 7.4E-26 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CIG75_RS18760 668ee804eded045efe8e61c5919e29f4 72 Pfam PF02416 mttA/Hcf106 family 5 55 6.6E-23 T 28-03-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 CIG75_RS18760 668ee804eded045efe8e61c5919e29f4 72 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 2 65 18.007 T 28-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 CIG75_RS18760 668ee804eded045efe8e61c5919e29f4 72 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 22 41 2.6E-5 T 28-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 CIG75_RS18760 668ee804eded045efe8e61c5919e29f4 72 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 2 22 2.6E-5 T 28-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 CIG75_RS18760 668ee804eded045efe8e61c5919e29f4 72 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 5 50 6.8E-20 T 28-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 CIG75_RS07080 1cb57cfdb77980df488d981066701408 427 Gene3D G3DSA:3.10.350.10 1 48 3.5E-7 T 28-03-2018 CIG75_RS07080 1cb57cfdb77980df488d981066701408 427 SMART SM00257 55 98 2.7E-7 T 28-03-2018 IPR018392 LysM domain CIG75_RS07080 1cb57cfdb77980df488d981066701408 427 SMART SM00257 3 46 1.2E-7 T 28-03-2018 IPR018392 LysM domain CIG75_RS07080 1cb57cfdb77980df488d981066701408 427 SUPERFAMILY SSF54106 54 99 1.7E-6 T 28-03-2018 IPR018392 LysM domain CIG75_RS07080 1cb57cfdb77980df488d981066701408 427 SUPERFAMILY SSF54106 2 46 6.67E-8 T 28-03-2018 IPR018392 LysM domain CIG75_RS07080 1cb57cfdb77980df488d981066701408 427 Gene3D G3DSA:3.20.20.80 110 332 6.5E-13 T 28-03-2018 CIG75_RS07080 1cb57cfdb77980df488d981066701408 427 SMART SM00636 113 407 0.0046 T 28-03-2018 IPR011583 Chitinase II GO:0008061 CIG75_RS07080 1cb57cfdb77980df488d981066701408 427 Pfam PF01476 LysM domain 4 46 1.2E-6 T 28-03-2018 IPR018392 LysM domain CIG75_RS07080 1cb57cfdb77980df488d981066701408 427 Pfam PF01476 LysM domain 56 98 1.6E-7 T 28-03-2018 IPR018392 LysM domain CIG75_RS07080 1cb57cfdb77980df488d981066701408 427 Gene3D G3DSA:3.10.350.10 49 108 2.7E-8 T 28-03-2018 CIG75_RS07080 1cb57cfdb77980df488d981066701408 427 Gene3D G3DSA:3.10.50.10 333 379 4.0E-6 T 28-03-2018 IPR029070 Chitinase insertion domain CIG75_RS07080 1cb57cfdb77980df488d981066701408 427 SUPERFAMILY SSF51445 180 321 2.56E-18 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CIG75_RS07080 1cb57cfdb77980df488d981066701408 427 SUPERFAMILY SSF51445 379 401 2.56E-18 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CIG75_RS07080 1cb57cfdb77980df488d981066701408 427 Pfam PF00704 Glycosyl hydrolases family 18 189 401 3.3E-7 T 28-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 CIG75_RS16995 8218e1ac6340393bca21e28529518aee 157 Gene3D G3DSA:3.90.960.10 1 157 2.2E-37 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CIG75_RS16995 8218e1ac6340393bca21e28529518aee 157 TIGRFAM TIGR00011 YbaK_EbsC: Cys-tRNA(Pro) deacylase 5 154 2.6E-48 T 28-03-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC CIG75_RS16995 8218e1ac6340393bca21e28529518aee 157 PIRSF PIRSF006181 1 157 3.6E-53 T 28-03-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC CIG75_RS16995 8218e1ac6340393bca21e28529518aee 157 Pfam PF04073 Aminoacyl-tRNA editing domain 31 144 2.2E-20 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CIG75_RS16995 8218e1ac6340393bca21e28529518aee 157 SUPERFAMILY SSF55826 5 155 1.7E-38 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CIG75_RS10490 c77c9a6e2c7d715ec0417221afdc0eb1 208 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 6 195 1.4E-36 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CIG75_RS10490 c77c9a6e2c7d715ec0417221afdc0eb1 208 SUPERFAMILY SSF56529 3 197 7.98E-52 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CIG75_RS10490 c77c9a6e2c7d715ec0417221afdc0eb1 208 Gene3D G3DSA:3.90.850.10 1 208 5.2E-53 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CIG75_RS12450 0b1ecf11799929d802ea594e08ae1961 223 TIGRFAM TIGR00719 sda_beta: L-serine dehydratase, iron-sulfur-dependent, beta subunit 5 202 4.6E-69 T 28-03-2018 IPR004643 Iron-sulphur-dependent L-serine dehydratase beta subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CIG75_RS12450 0b1ecf11799929d802ea594e08ae1961 223 Pfam PF03315 Serine dehydratase beta chain 14 132 8.7E-13 T 28-03-2018 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CIG75_RS12450 0b1ecf11799929d802ea594e08ae1961 223 SUPERFAMILY SSF143548 20 138 1.1E-28 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 CIG75_RS12450 0b1ecf11799929d802ea594e08ae1961 223 PIRSF PIRSF036692 2 222 6.2E-90 T 28-03-2018 IPR004643 Iron-sulphur-dependent L-serine dehydratase beta subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CIG75_RS12450 0b1ecf11799929d802ea594e08ae1961 223 Pfam PF01842 ACT domain 156 212 1.2E-8 T 28-03-2018 IPR002912 ACT domain CIG75_RS12450 0b1ecf11799929d802ea594e08ae1961 223 SUPERFAMILY SSF55021 139 220 1.54E-13 T 28-03-2018 CIG75_RS12450 0b1ecf11799929d802ea594e08ae1961 223 Gene3D G3DSA:3.30.1330.90 14 138 6.5E-24 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 CIG75_RS12450 0b1ecf11799929d802ea594e08ae1961 223 Gene3D G3DSA:3.30.70.260 149 222 1.4E-14 T 28-03-2018 CIG75_RS11135 579a7d32db0dbbfa0d69de69ae26a02d 424 SUPERFAMILY SSF48452 193 264 6.54E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS11135 579a7d32db0dbbfa0d69de69ae26a02d 424 SUPERFAMILY SSF48452 307 410 6.54E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS11135 579a7d32db0dbbfa0d69de69ae26a02d 424 Pfam PF01381 Helix-turn-helix 11 64 1.8E-12 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS11135 579a7d32db0dbbfa0d69de69ae26a02d 424 SMART SM00028 151 184 230.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS11135 579a7d32db0dbbfa0d69de69ae26a02d 424 SMART SM00028 229 262 42.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS11135 579a7d32db0dbbfa0d69de69ae26a02d 424 SMART SM00028 193 226 0.034 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS11135 579a7d32db0dbbfa0d69de69ae26a02d 424 SMART SM00028 305 338 180.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS11135 579a7d32db0dbbfa0d69de69ae26a02d 424 SMART SM00028 343 376 26.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS11135 579a7d32db0dbbfa0d69de69ae26a02d 424 SUPERFAMILY SSF47413 2 68 7.32E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CIG75_RS11135 579a7d32db0dbbfa0d69de69ae26a02d 424 Gene3D G3DSA:1.25.40.10 205 288 2.3E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS11135 579a7d32db0dbbfa0d69de69ae26a02d 424 Gene3D G3DSA:1.25.40.10 289 420 5.2E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS11135 579a7d32db0dbbfa0d69de69ae26a02d 424 Gene3D G3DSA:1.10.260.40 1 78 3.7E-16 T 28-03-2018 CIG75_RS11135 579a7d32db0dbbfa0d69de69ae26a02d 424 Gene3D G3DSA:1.25.40.10 79 149 2.8E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS11135 579a7d32db0dbbfa0d69de69ae26a02d 424 SMART SM00530 10 64 8.4E-14 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS11135 579a7d32db0dbbfa0d69de69ae26a02d 424 Pfam PF13432 Tetratricopeptide repeat 199 248 0.017 T 28-03-2018 CIG75_RS11135 579a7d32db0dbbfa0d69de69ae26a02d 424 Pfam PF13432 Tetratricopeptide repeat 78 139 0.0038 T 28-03-2018 CIG75_RS11135 579a7d32db0dbbfa0d69de69ae26a02d 424 SUPERFAMILY SSF48452 112 250 3.26E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS11135 579a7d32db0dbbfa0d69de69ae26a02d 424 Gene3D G3DSA:1.10.150.200 150 204 0.0012 T 28-03-2018 CIG75_RS02210 12a225120cf2a00765cd52a64ff8bf76 296 PIRSF PIRSF006483 7 295 1.4E-97 T 28-03-2018 IPR003740 Uncharacterised membrane protein YitT CIG75_RS02210 12a225120cf2a00765cd52a64ff8bf76 296 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 233 287 8.2E-23 T 28-03-2018 IPR019264 Domain of unknown function DUF2179 CIG75_RS02210 12a225120cf2a00765cd52a64ff8bf76 296 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 25 225 2.2E-68 T 28-03-2018 IPR003740 Uncharacterised membrane protein YitT CIG75_RS12230 b73b990dedd4b42bd34515a4f355f160 375 Gene3D G3DSA:3.90.1720.10 243 375 7.1E-38 T 28-03-2018 CIG75_RS12230 b73b990dedd4b42bd34515a4f355f160 375 Gene3D G3DSA:3.10.350.10 163 242 6.8E-15 T 28-03-2018 CIG75_RS12230 b73b990dedd4b42bd34515a4f355f160 375 SUPERFAMILY SSF54106 168 211 7.98E-11 T 28-03-2018 IPR018392 LysM domain CIG75_RS12230 b73b990dedd4b42bd34515a4f355f160 375 SUPERFAMILY SSF54001 240 374 4.17E-39 T 28-03-2018 CIG75_RS12230 b73b990dedd4b42bd34515a4f355f160 375 Gene3D G3DSA:3.30.457.10 76 151 1.0E-5 T 28-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CIG75_RS12230 b73b990dedd4b42bd34515a4f355f160 375 SMART SM00257 168 211 5.8E-13 T 28-03-2018 IPR018392 LysM domain CIG75_RS12230 b73b990dedd4b42bd34515a4f355f160 375 Pfam PF07833 Copper amine oxidase N-terminal domain 72 152 3.6E-9 T 28-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CIG75_RS12230 b73b990dedd4b42bd34515a4f355f160 375 Pfam PF00877 NlpC/P60 family 261 370 3.5E-28 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CIG75_RS12230 b73b990dedd4b42bd34515a4f355f160 375 SUPERFAMILY SSF55383 74 149 7.32E-7 T 28-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CIG75_RS12230 b73b990dedd4b42bd34515a4f355f160 375 Pfam PF01476 LysM domain 169 211 1.9E-13 T 28-03-2018 IPR018392 LysM domain CIG75_RS03650 5917fb93866f7b322c2dcdf62791a04b 236 TIGRFAM TIGR01768 GGGP-family: geranylgeranylglyceryl phosphate synthase family protein 13 224 6.2E-55 T 28-03-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 CIG75_RS03650 5917fb93866f7b322c2dcdf62791a04b 236 Pfam PF01884 PcrB family 9 226 4.5E-61 T 28-03-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 CIG75_RS03650 5917fb93866f7b322c2dcdf62791a04b 236 Hamap MF_00112 Geranylgeranylglyceryl phosphate synthase [pcrB]. 8 235 25.406 T 28-03-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 CIG75_RS03650 5917fb93866f7b322c2dcdf62791a04b 236 SUPERFAMILY SSF51395 9 225 4.03E-40 T 28-03-2018 CIG75_RS03650 5917fb93866f7b322c2dcdf62791a04b 236 Gene3D G3DSA:3.20.20.390 5 231 3.4E-29 T 28-03-2018 CIG75_RS08365 e5b7e86172fdd4aec0b3a516dac020c3 383 SUPERFAMILY SSF63999 176 335 3.27E-29 T 28-03-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CIG75_RS08365 e5b7e86172fdd4aec0b3a516dac020c3 383 Gene3D G3DSA:3.40.50.10240 172 255 1.6E-10 T 28-03-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CIG75_RS08365 e5b7e86172fdd4aec0b3a516dac020c3 383 Pfam PF12555 Thiamine pyrophosphokinase C terminal 331 382 5.6E-9 T 28-03-2018 IPR022215 Thiamine pyrophosphokinase C-terminal CIG75_RS01920 e358ee90f612a1c72c65496ba3cf687a 70 Hamap MF_01396 ATP synthase subunit c [atpH]. 2 67 14.407 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CIG75_RS01920 e358ee90f612a1c72c65496ba3cf687a 70 SUPERFAMILY SSF81333 4 67 1.57E-17 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CIG75_RS01920 e358ee90f612a1c72c65496ba3cf687a 70 Gene3D G3DSA:1.20.20.10 2 68 2.7E-18 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CIG75_RS01920 e358ee90f612a1c72c65496ba3cf687a 70 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 12 66 1.6E-24 T 28-03-2018 IPR005953 ATP synthase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CIG75_RS01920 e358ee90f612a1c72c65496ba3cf687a 70 ProSitePatterns PS00605 ATP synthase c subunit signature. 32 53 - T 28-03-2018 IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CIG75_RS01920 e358ee90f612a1c72c65496ba3cf687a 70 Pfam PF00137 ATP synthase subunit C 4 66 8.4E-13 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CIG75_RS01920 e358ee90f612a1c72c65496ba3cf687a 70 PRINTS PR00124 ATP synthase C subunit signature 4 23 7.0E-15 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CIG75_RS01920 e358ee90f612a1c72c65496ba3cf687a 70 PRINTS PR00124 ATP synthase C subunit signature 42 67 7.0E-15 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CIG75_RS01920 e358ee90f612a1c72c65496ba3cf687a 70 PRINTS PR00124 ATP synthase C subunit signature 25 40 7.0E-15 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CIG75_RS02425 7e8b75c968323e2da85820413f7933de 389 Gene3D G3DSA:3.40.50.2000 1 215 1.1E-53 T 28-03-2018 CIG75_RS02425 7e8b75c968323e2da85820413f7933de 389 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 24 371 1.5E-91 T 28-03-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001 CIG75_RS02425 7e8b75c968323e2da85820413f7933de 389 Gene3D G3DSA:3.40.50.2000 216 349 1.9E-24 T 28-03-2018 CIG75_RS02425 7e8b75c968323e2da85820413f7933de 389 TIGRFAM TIGR03568 NeuC_NnaA: UDP-N-acetyl-D-glucosamine 2-epimerase, UDP-hydrolysing 4 370 3.4E-144 T 28-03-2018 IPR020004 UDP-N-acetylglucosamine 2-epimerase,UDP-hydrolysing GO:0004553|GO:0006047 KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-4085001 CIG75_RS02425 7e8b75c968323e2da85820413f7933de 389 SUPERFAMILY SSF53756 3 384 3.45E-96 T 28-03-2018 CIG75_RS13640 a732e9f0285ecf485283ec76df7dc503 218 Gene3D G3DSA:1.10.3720.10 2 218 4.6E-43 T 28-03-2018 CIG75_RS13640 a732e9f0285ecf485283ec76df7dc503 218 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 28 216 1.2E-24 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CIG75_RS13640 a732e9f0285ecf485283ec76df7dc503 218 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 11 213 5.4E-72 T 28-03-2018 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 CIG75_RS13640 a732e9f0285ecf485283ec76df7dc503 218 SUPERFAMILY SSF161098 5 213 1.7E-54 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CIG75_RS05060 8332c064066b6ed8c2744ee47f8e18af 256 Gene3D G3DSA:3.40.50.720 1 256 1.6E-46 T 28-03-2018 CIG75_RS05060 8332c064066b6ed8c2744ee47f8e18af 256 SUPERFAMILY SSF51735 7 255 1.21E-68 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS05060 8332c064066b6ed8c2744ee47f8e18af 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 1.5E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS05060 8332c064066b6ed8c2744ee47f8e18af 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 1.5E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS05060 8332c064066b6ed8c2744ee47f8e18af 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 1.5E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS05060 8332c064066b6ed8c2744ee47f8e18af 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 1.5E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS05060 8332c064066b6ed8c2744ee47f8e18af 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 1.5E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS05060 8332c064066b6ed8c2744ee47f8e18af 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 253 3.6E-89 T 28-03-2018 CIG75_RS05060 8332c064066b6ed8c2744ee47f8e18af 256 PIRSF PIRSF000094 2 256 3.1E-106 T 28-03-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CIG75_RS12515 c69213daaa455810b2d86f3e8f66b6f6 815 Gene3D G3DSA:3.40.50.300 476 719 8.1E-22 T 28-03-2018 CIG75_RS12515 c69213daaa455810b2d86f3e8f66b6f6 815 SMART SM00487 270 469 1.1E-21 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CIG75_RS12515 c69213daaa455810b2d86f3e8f66b6f6 815 Gene3D G3DSA:3.40.50.300 284 438 6.7E-29 T 28-03-2018 CIG75_RS12515 c69213daaa455810b2d86f3e8f66b6f6 815 SMART SM00490 574 671 2.8E-9 T 28-03-2018 IPR001650 Helicase, C-terminal CIG75_RS12515 c69213daaa455810b2d86f3e8f66b6f6 815 Gene3D G3DSA:1.10.10.10 196 283 0.0029 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS12515 c69213daaa455810b2d86f3e8f66b6f6 815 Pfam PF00271 Helicase conserved C-terminal domain 586 670 7.1E-8 T 28-03-2018 IPR001650 Helicase, C-terminal CIG75_RS12515 c69213daaa455810b2d86f3e8f66b6f6 815 TIGRFAM TIGR00595 priA: primosomal protein N' 298 810 1.2E-197 T 28-03-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 CIG75_RS12515 c69213daaa455810b2d86f3e8f66b6f6 815 Hamap MF_00983 Probable primosomal protein N' [priA]. 12 814 24.309 T 28-03-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 CIG75_RS12515 c69213daaa455810b2d86f3e8f66b6f6 815 SUPERFAMILY SSF52540 543 708 4.04E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS12515 c69213daaa455810b2d86f3e8f66b6f6 815 SUPERFAMILY SSF52540 271 447 1.56E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS12515 c69213daaa455810b2d86f3e8f66b6f6 815 Pfam PF00270 DEAD/DEAH box helicase 276 437 7.0E-17 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CIG75_RS08500 e4aba2b45e9131e534672aa7b1821dc0 110 SUPERFAMILY SSF50249 2 109 1.47E-30 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CIG75_RS08500 e4aba2b45e9131e534672aa7b1821dc0 110 Gene3D G3DSA:2.40.50.140 1 110 5.1E-20 T 28-03-2018 CIG75_RS08500 e4aba2b45e9131e534672aa7b1821dc0 110 TIGRFAM TIGR02222 chap_CsaA: export-related chaperone protein CsaA 4 109 4.9E-47 T 28-03-2018 IPR008231 Probable chaperone CsaA CIG75_RS08500 e4aba2b45e9131e534672aa7b1821dc0 110 Pfam PF01588 Putative tRNA binding domain 12 108 2.3E-15 T 28-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 CIG75_RS02750 72fd3b95a1e15c015d72aad61ddb3f63 254 Gene3D G3DSA:3.90.1530.10 5 86 2.1E-10 T 28-03-2018 CIG75_RS02750 72fd3b95a1e15c015d72aad61ddb3f63 254 PIRSF PIRSF032543 1 254 6.2E-46 T 28-03-2018 IPR016999 Uncharacterised conserved protein UCP032543, ParB-like nuclease CIG75_RS02750 72fd3b95a1e15c015d72aad61ddb3f63 254 SUPERFAMILY SSF110849 7 223 1.31E-23 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CIG75_RS02750 72fd3b95a1e15c015d72aad61ddb3f63 254 SMART SM00470 9 92 1.1E-6 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CIG75_RS02750 72fd3b95a1e15c015d72aad61ddb3f63 254 Pfam PF02195 ParB-like nuclease domain 23 80 1.4E-9 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CIG75_RS18640 f2c413693f3183c9f86bd36e8e863943 246 Pfam PF00005 ABC transporter 21 161 7.9E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS18640 f2c413693f3183c9f86bd36e8e863943 246 SUPERFAMILY SSF52540 5 225 3.77E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS18640 f2c413693f3183c9f86bd36e8e863943 246 SMART SM00382 30 209 1.4E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS18640 f2c413693f3183c9f86bd36e8e863943 246 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS18640 f2c413693f3183c9f86bd36e8e863943 246 Gene3D G3DSA:3.40.50.300 2 241 1.3E-57 T 28-03-2018 CIG75_RS19530 18503d4fe1982ab43cbb3f880f6b7d10 839 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 405 567 1.7E-38 T 28-03-2018 IPR000160 GGDEF domain CIG75_RS19530 18503d4fe1982ab43cbb3f880f6b7d10 839 SUPERFAMILY SSF55785 302 402 1.1E-14 T 28-03-2018 IPR000014 PAS domain CIG75_RS19530 18503d4fe1982ab43cbb3f880f6b7d10 839 Gene3D G3DSA:3.30.450.20 261 406 2.0E-18 T 28-03-2018 CIG75_RS19530 18503d4fe1982ab43cbb3f880f6b7d10 839 Gene3D G3DSA:3.30.450.20 94 247 1.8E-4 T 28-03-2018 CIG75_RS19530 18503d4fe1982ab43cbb3f880f6b7d10 839 SUPERFAMILY SSF55073 413 570 2.04E-47 T 28-03-2018 IPR029787 Nucleotide cyclase CIG75_RS19530 18503d4fe1982ab43cbb3f880f6b7d10 839 Gene3D G3DSA:3.20.20.450 571 835 1.6E-106 T 28-03-2018 IPR001633 EAL domain CIG75_RS19530 18503d4fe1982ab43cbb3f880f6b7d10 839 Gene3D G3DSA:3.30.70.270 407 570 8.4E-59 T 28-03-2018 CIG75_RS19530 18503d4fe1982ab43cbb3f880f6b7d10 839 Pfam PF13426 PAS domain 300 396 3.3E-9 T 28-03-2018 IPR000014 PAS domain CIG75_RS19530 18503d4fe1982ab43cbb3f880f6b7d10 839 SMART SM00267 396 569 1.1E-61 T 28-03-2018 IPR000160 GGDEF domain CIG75_RS19530 18503d4fe1982ab43cbb3f880f6b7d10 839 SMART SM00052 579 825 2.8E-130 T 28-03-2018 IPR001633 EAL domain CIG75_RS19530 18503d4fe1982ab43cbb3f880f6b7d10 839 Pfam PF00563 EAL domain 587 820 3.6E-74 T 28-03-2018 IPR001633 EAL domain CIG75_RS19530 18503d4fe1982ab43cbb3f880f6b7d10 839 SMART SM00091 289 355 2.2E-5 T 28-03-2018 IPR000014 PAS domain CIG75_RS19530 18503d4fe1982ab43cbb3f880f6b7d10 839 SUPERFAMILY SSF141868 584 834 3.4E-96 T 28-03-2018 IPR001633 EAL domain CIG75_RS19530 18503d4fe1982ab43cbb3f880f6b7d10 839 Pfam PF00990 Diguanylate cyclase, GGDEF domain 408 564 5.9E-48 T 28-03-2018 IPR000160 GGDEF domain CIG75_RS19530 18503d4fe1982ab43cbb3f880f6b7d10 839 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 286 402 3.6E-17 T 28-03-2018 IPR000014 PAS domain CIG75_RS03965 bd1a64745bf46eb445b3c924d28821c3 396 SMART SM00835 54 196 1.6E-16 T 28-03-2018 IPR006045 Cupin 1 GO:0045735 CIG75_RS03965 bd1a64745bf46eb445b3c924d28821c3 396 SMART SM00835 232 373 3.7E-34 T 28-03-2018 IPR006045 Cupin 1 GO:0045735 CIG75_RS03965 bd1a64745bf46eb445b3c924d28821c3 396 SUPERFAMILY SSF51182 21 382 6.34E-102 T 28-03-2018 IPR011051 RmlC-like cupin domain CIG75_RS03965 bd1a64745bf46eb445b3c924d28821c3 396 Pfam PF00190 Cupin 64 190 1.9E-17 T 28-03-2018 IPR006045 Cupin 1 GO:0045735 CIG75_RS03965 bd1a64745bf46eb445b3c924d28821c3 396 Pfam PF00190 Cupin 234 370 5.2E-24 T 28-03-2018 IPR006045 Cupin 1 GO:0045735 CIG75_RS03965 bd1a64745bf46eb445b3c924d28821c3 396 Gene3D G3DSA:2.60.120.10 216 386 7.2E-38 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CIG75_RS03965 bd1a64745bf46eb445b3c924d28821c3 396 Gene3D G3DSA:2.60.120.10 9 212 9.6E-43 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CIG75_RS03965 bd1a64745bf46eb445b3c924d28821c3 396 ProSitePatterns PS00233 Chitin-binding type R&R domain signature. 293 318 - T 28-03-2018 IPR031311 Chitin-binding type R&R consensus CIG75_RS03965 bd1a64745bf46eb445b3c924d28821c3 396 TIGRFAM TIGR03404 bicupin_oxalic: bicupin, oxalate decarboxylase family 18 383 8.4E-175 T 28-03-2018 IPR017774 Bicupin, oxalate decarboxylase/oxidase GO:0033609 KEGG: 00630+4.1.1.2|MetaCyc: PWY-6698 CIG75_RS05560 a7f7e908b0e51a5b33ed3d95a477bdbd 584 SUPERFAMILY SSF51621 1 75 8.72E-102 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CIG75_RS05560 a7f7e908b0e51a5b33ed3d95a477bdbd 584 SUPERFAMILY SSF51621 166 337 8.72E-102 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CIG75_RS05560 a7f7e908b0e51a5b33ed3d95a477bdbd 584 SUPERFAMILY SSF52009 465 581 1.57E-30 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CIG75_RS05560 a7f7e908b0e51a5b33ed3d95a477bdbd 584 SUPERFAMILY SSF50800 70 165 2.09E-27 T 28-03-2018 IPR011037 Pyruvate kinase-like, insert domain CIG75_RS05560 a7f7e908b0e51a5b33ed3d95a477bdbd 584 PRINTS PR01050 Pyruvate kinase family signature 292 310 1.8E-76 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CIG75_RS05560 a7f7e908b0e51a5b33ed3d95a477bdbd 584 PRINTS PR01050 Pyruvate kinase family signature 59 75 1.8E-76 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CIG75_RS05560 a7f7e908b0e51a5b33ed3d95a477bdbd 584 PRINTS PR01050 Pyruvate kinase family signature 311 327 1.8E-76 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CIG75_RS05560 a7f7e908b0e51a5b33ed3d95a477bdbd 584 PRINTS PR01050 Pyruvate kinase family signature 185 199 1.8E-76 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CIG75_RS05560 a7f7e908b0e51a5b33ed3d95a477bdbd 584 PRINTS PR01050 Pyruvate kinase family signature 215 241 1.8E-76 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CIG75_RS05560 a7f7e908b0e51a5b33ed3d95a477bdbd 584 PRINTS PR01050 Pyruvate kinase family signature 242 266 1.8E-76 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CIG75_RS05560 a7f7e908b0e51a5b33ed3d95a477bdbd 584 PRINTS PR01050 Pyruvate kinase family signature 267 291 1.8E-76 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CIG75_RS05560 a7f7e908b0e51a5b33ed3d95a477bdbd 584 Gene3D G3DSA:3.20.20.60 1 82 2.0E-21 T 28-03-2018 CIG75_RS05560 a7f7e908b0e51a5b33ed3d95a477bdbd 584 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 2 472 4.7E-185 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CIG75_RS05560 a7f7e908b0e51a5b33ed3d95a477bdbd 584 Pfam PF00391 PEP-utilising enzyme, mobile domain 502 574 6.4E-22 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CIG75_RS05560 a7f7e908b0e51a5b33ed3d95a477bdbd 584 Gene3D G3DSA:2.40.33.10 83 165 4.5E-30 T 28-03-2018 CIG75_RS05560 a7f7e908b0e51a5b33ed3d95a477bdbd 584 Gene3D G3DSA:3.40.1380.20 320 473 4.1E-53 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CIG75_RS05560 a7f7e908b0e51a5b33ed3d95a477bdbd 584 SUPERFAMILY SSF52935 321 473 2.88E-42 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CIG75_RS05560 a7f7e908b0e51a5b33ed3d95a477bdbd 584 Gene3D G3DSA:3.50.30.10 476 584 3.7E-30 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CIG75_RS05560 a7f7e908b0e51a5b33ed3d95a477bdbd 584 Pfam PF00224 Pyruvate kinase, barrel domain 1 339 1.0E-147 T 28-03-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CIG75_RS05560 a7f7e908b0e51a5b33ed3d95a477bdbd 584 Gene3D G3DSA:3.20.20.60 166 319 1.0E-63 T 28-03-2018 CIG75_RS05560 a7f7e908b0e51a5b33ed3d95a477bdbd 584 Pfam PF02887 Pyruvate kinase, alpha/beta domain 357 470 1.4E-35 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CIG75_RS09055 b08dbbab970c606f8d49dbb0610ef525 453 Pfam PF01523 Putative modulator of DNA gyrase 24 314 1.1E-46 T 28-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 CIG75_RS09055 b08dbbab970c606f8d49dbb0610ef525 453 SUPERFAMILY SSF111283 1 453 3.79E-103 T 28-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 CIG75_RS09055 b08dbbab970c606f8d49dbb0610ef525 453 Gene3D G3DSA:3.30.2290.10 1 217 1.1E-31 T 28-03-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal domain CIG75_RS07850 5f5e57fd1fcc8a6e0cfe536e4bf348fc 773 Gene3D G3DSA:1.10.8.60 490 582 1.2E-32 T 28-03-2018 CIG75_RS07850 5f5e57fd1fcc8a6e0cfe536e4bf348fc 773 Gene3D G3DSA:2.30.130.40 2 116 2.7E-26 T 28-03-2018 CIG75_RS07850 5f5e57fd1fcc8a6e0cfe536e4bf348fc 773 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 671 690 6.3E-55 T 28-03-2018 CIG75_RS07850 5f5e57fd1fcc8a6e0cfe536e4bf348fc 773 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 701 720 6.3E-55 T 28-03-2018 CIG75_RS07850 5f5e57fd1fcc8a6e0cfe536e4bf348fc 773 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 354 373 6.3E-55 T 28-03-2018 CIG75_RS07850 5f5e57fd1fcc8a6e0cfe536e4bf348fc 773 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 593 609 6.3E-55 T 28-03-2018 CIG75_RS07850 5f5e57fd1fcc8a6e0cfe536e4bf348fc 773 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 724 742 6.3E-55 T 28-03-2018 CIG75_RS07850 5f5e57fd1fcc8a6e0cfe536e4bf348fc 773 PIRSF PIRSF001174 2 773 0.0 T 28-03-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 CIG75_RS07850 5f5e57fd1fcc8a6e0cfe536e4bf348fc 773 Gene3D G3DSA:3.30.230.10 584 770 2.4E-65 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CIG75_RS07850 5f5e57fd1fcc8a6e0cfe536e4bf348fc 773 Gene3D G3DSA:3.40.50.300 312 489 3.2E-32 T 28-03-2018 CIG75_RS07850 5f5e57fd1fcc8a6e0cfe536e4bf348fc 773 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 568 770 6.0E-98 T 28-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 CIG75_RS07850 5f5e57fd1fcc8a6e0cfe536e4bf348fc 773 SMART SM00464 8 200 1.8E-73 T 28-03-2018 IPR003111 Lon, substrate-binding domain CIG75_RS07850 5f5e57fd1fcc8a6e0cfe536e4bf348fc 773 SUPERFAMILY SSF52540 311 583 1.76E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS07850 5f5e57fd1fcc8a6e0cfe536e4bf348fc 773 Hamap MF_01973 Lon protease [lon]. 9 770 72.577 T 28-03-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 CIG75_RS07850 5f5e57fd1fcc8a6e0cfe536e4bf348fc 773 TIGRFAM TIGR00763 lon: endopeptidase La 10 769 0.0 T 28-03-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 CIG75_RS07850 5f5e57fd1fcc8a6e0cfe536e4bf348fc 773 SUPERFAMILY SSF54211 593 767 2.84E-56 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CIG75_RS07850 5f5e57fd1fcc8a6e0cfe536e4bf348fc 773 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 8 199 1.8E-39 T 28-03-2018 IPR003111 Lon, substrate-binding domain CIG75_RS07850 5f5e57fd1fcc8a6e0cfe536e4bf348fc 773 Gene3D G3DSA:1.10.4060.10 119 209 1.2E-29 T 28-03-2018 CIG75_RS07850 5f5e57fd1fcc8a6e0cfe536e4bf348fc 773 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 350 487 4.6E-23 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CIG75_RS07850 5f5e57fd1fcc8a6e0cfe536e4bf348fc 773 SMART SM00382 346 491 1.7E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS07850 5f5e57fd1fcc8a6e0cfe536e4bf348fc 773 SUPERFAMILY SSF88697 8 198 3.48E-47 T 28-03-2018 IPR015947 PUA-like domain CIG75_RS01715 5997a8d2d65978b5fa5e2549fe5f0385 162 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 4 147 1.1E-45 T 28-03-2018 IPR023635 Peptide deformylase CIG75_RS01715 5997a8d2d65978b5fa5e2549fe5f0385 162 PRINTS PR01576 Peptide deformylase signature 101 119 1.4E-33 T 28-03-2018 IPR023635 Peptide deformylase CIG75_RS01715 5997a8d2d65978b5fa5e2549fe5f0385 162 PRINTS PR01576 Peptide deformylase signature 33 62 1.4E-33 T 28-03-2018 IPR023635 Peptide deformylase CIG75_RS01715 5997a8d2d65978b5fa5e2549fe5f0385 162 PRINTS PR01576 Peptide deformylase signature 89 100 1.4E-33 T 28-03-2018 IPR023635 Peptide deformylase CIG75_RS01715 5997a8d2d65978b5fa5e2549fe5f0385 162 PRINTS PR01576 Peptide deformylase signature 120 149 1.4E-33 T 28-03-2018 IPR023635 Peptide deformylase CIG75_RS01715 5997a8d2d65978b5fa5e2549fe5f0385 162 SUPERFAMILY SSF56420 2 150 1.27E-55 T 28-03-2018 IPR023635 Peptide deformylase CIG75_RS01715 5997a8d2d65978b5fa5e2549fe5f0385 162 Hamap MF_00163 Peptide deformylase [def]. 2 161 27.995 T 28-03-2018 IPR023635 Peptide deformylase CIG75_RS01715 5997a8d2d65978b5fa5e2549fe5f0385 162 PIRSF PIRSF004749 1 156 6.0E-48 T 28-03-2018 IPR023635 Peptide deformylase CIG75_RS01715 5997a8d2d65978b5fa5e2549fe5f0385 162 Gene3D G3DSA:3.90.45.10 1 160 2.6E-55 T 28-03-2018 IPR023635 Peptide deformylase CIG75_RS01715 5997a8d2d65978b5fa5e2549fe5f0385 162 Pfam PF01327 Polypeptide deformylase 4 147 2.4E-46 T 28-03-2018 IPR023635 Peptide deformylase CIG75_RS07985 6c7f7d3e32ec5826c6d733dc2a06612d 449 Pfam PF01636 Phosphotransferase enzyme family 43 262 8.1E-22 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CIG75_RS07985 6c7f7d3e32ec5826c6d733dc2a06612d 449 SUPERFAMILY SSF56112 22 332 4.52E-45 T 28-03-2018 IPR011009 Protein kinase-like domain CIG75_RS07985 6c7f7d3e32ec5826c6d733dc2a06612d 449 Gene3D G3DSA:3.90.1200.10 99 428 1.7E-23 T 28-03-2018 CIG75_RS07985 6c7f7d3e32ec5826c6d733dc2a06612d 449 Gene3D G3DSA:3.30.200.20 2 98 2.6E-13 T 28-03-2018 CIG75_RS07985 6c7f7d3e32ec5826c6d733dc2a06612d 449 TIGRFAM TIGR02906 spore_CotS: spore coat protein, CotS family 30 338 2.9E-66 T 28-03-2018 IPR014255 Spore coat protein CotS CIG75_RS19590 9a62c1b9162333d717c74b14b1d7d44d 314 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 26 221 1.1E-24 T 28-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CIG75_RS19590 9a62c1b9162333d717c74b14b1d7d44d 314 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 253 314 5.0E-23 T 28-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CIG75_RS19590 9a62c1b9162333d717c74b14b1d7d44d 314 SMART SM00662 20 227 1.1E-104 T 28-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CIG75_RS19590 9a62c1b9162333d717c74b14b1d7d44d 314 SUPERFAMILY SSF47789 247 311 1.31E-24 T 28-03-2018 CIG75_RS19590 9a62c1b9162333d717c74b14b1d7d44d 314 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 240 305 3.7E-29 T 28-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CIG75_RS19590 9a62c1b9162333d717c74b14b1d7d44d 314 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 1 313 37.978 T 28-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CIG75_RS19590 9a62c1b9162333d717c74b14b1d7d44d 314 Gene3D G3DSA:3.30.1360.10 109 224 4.2E-28 T 28-03-2018 CIG75_RS19590 9a62c1b9162333d717c74b14b1d7d44d 314 Gene3D G3DSA:3.30.1360.10 1 86 1.2E-20 T 28-03-2018 CIG75_RS19590 9a62c1b9162333d717c74b14b1d7d44d 314 SUPERFAMILY SSF55257 6 50 4.91E-32 T 28-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CIG75_RS19590 9a62c1b9162333d717c74b14b1d7d44d 314 SUPERFAMILY SSF55257 172 225 4.91E-32 T 28-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CIG75_RS19590 9a62c1b9162333d717c74b14b1d7d44d 314 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 20 312 4.2E-125 T 28-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CIG75_RS19590 9a62c1b9162333d717c74b14b1d7d44d 314 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 57 152 4.0E-26 T 28-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CIG75_RS19590 9a62c1b9162333d717c74b14b1d7d44d 314 Gene3D G3DSA:1.10.150.20 241 314 8.6E-27 T 28-03-2018 CIG75_RS19590 9a62c1b9162333d717c74b14b1d7d44d 314 SUPERFAMILY SSF56553 50 171 3.66E-46 T 28-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CIG75_RS19720 f5f08c881a20d0d6f419cee82915d039 276 SMART SM01383 42 118 3.2E-47 T 28-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS19720 f5f08c881a20d0d6f419cee82915d039 276 Gene3D G3DSA:2.30.30.30 118 195 6.8E-34 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 CIG75_RS19720 f5f08c881a20d0d6f419cee82915d039 276 ProSitePatterns PS00467 Ribosomal protein L2 signature. 218 229 - T 28-03-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CIG75_RS19720 f5f08c881a20d0d6f419cee82915d039 276 SUPERFAMILY SSF50249 3 125 7.2E-52 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CIG75_RS19720 f5f08c881a20d0d6f419cee82915d039 276 Gene3D G3DSA:4.10.950.10 197 275 8.6E-34 T 28-03-2018 IPR014726 Ribosomal protein L2, domain 3 CIG75_RS19720 f5f08c881a20d0d6f419cee82915d039 276 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 276 1.2E-133 T 28-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 CIG75_RS19720 f5f08c881a20d0d6f419cee82915d039 276 PIRSF PIRSF002158 3 276 1.0E-95 T 28-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS19720 f5f08c881a20d0d6f419cee82915d039 276 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 275 48.398 T 28-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 CIG75_RS19720 f5f08c881a20d0d6f419cee82915d039 276 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 125 251 2.4E-56 T 28-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 CIG75_RS19720 f5f08c881a20d0d6f419cee82915d039 276 SMART SM01382 124 253 1.1E-92 T 28-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 CIG75_RS19720 f5f08c881a20d0d6f419cee82915d039 276 SUPERFAMILY SSF50104 126 272 6.62E-60 T 28-03-2018 IPR008991 Translation protein SH3-like domain CIG75_RS19720 f5f08c881a20d0d6f419cee82915d039 276 Gene3D G3DSA:2.40.50.140 1 114 1.1E-49 T 28-03-2018 CIG75_RS19720 f5f08c881a20d0d6f419cee82915d039 276 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 117 1.2E-32 T 28-03-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS18800 7d96f96ae76e34c8a1fb8b4d6e2fe554 299 SUPERFAMILY SSF48317 11 177 1.83E-30 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CIG75_RS18800 7d96f96ae76e34c8a1fb8b4d6e2fe554 299 Pfam PF01569 PAP2 superfamily 63 174 6.8E-18 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CIG75_RS18800 7d96f96ae76e34c8a1fb8b4d6e2fe554 299 Gene3D G3DSA:1.20.144.10 19 184 2.2E-23 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CIG75_RS18800 7d96f96ae76e34c8a1fb8b4d6e2fe554 299 SMART SM00014 61 172 1.5E-14 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CIG75_RS01740 49debd72ee0e0a9bacf130e532713c90 214 ProSitePatterns PS00958 Transaldolase active site. 80 97 - T 28-03-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 CIG75_RS01740 49debd72ee0e0a9bacf130e532713c90 214 Hamap MF_00494 Probable transaldolase [tal]. 1 214 47.147 T 28-03-2018 IPR022999 Transaldolase type 3B, putative GO:0004801 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 CIG75_RS01740 49debd72ee0e0a9bacf130e532713c90 214 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 3 204 3.3E-56 T 28-03-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 CIG75_RS01740 49debd72ee0e0a9bacf130e532713c90 214 TIGRFAM TIGR00875 fsa_talC_mipB: fructose-6-phosphate aldolase 2 212 1.6E-99 T 28-03-2018 IPR004731 Transaldolase type 3B/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 CIG75_RS01740 49debd72ee0e0a9bacf130e532713c90 214 Gene3D G3DSA:3.20.20.70 1 214 2.3E-71 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CIG75_RS01740 49debd72ee0e0a9bacf130e532713c90 214 SUPERFAMILY SSF51569 2 213 2.09E-77 T 28-03-2018 CIG75_RS01740 49debd72ee0e0a9bacf130e532713c90 214 ProSitePatterns PS01054 Transaldolase signature 1. 24 32 - T 28-03-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 CIG75_RS09230 085aa280577bab21bedf28b40612aff6 375 Pfam PF00534 Glycosyl transferases group 1 180 354 1.3E-33 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CIG75_RS09230 085aa280577bab21bedf28b40612aff6 375 Gene3D G3DSA:3.40.50.2000 6 178 4.1E-6 T 28-03-2018 CIG75_RS09230 085aa280577bab21bedf28b40612aff6 375 SUPERFAMILY SSF53756 2 374 1.2E-66 T 28-03-2018 CIG75_RS09230 085aa280577bab21bedf28b40612aff6 375 Pfam PF13439 Glycosyltransferase Family 4 21 169 7.7E-12 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CIG75_RS09230 085aa280577bab21bedf28b40612aff6 375 Gene3D G3DSA:3.40.50.2000 179 362 2.8E-42 T 28-03-2018 CIG75_RS17695 b98d44fd48e47f31b3176178539f1114 128 Gene3D G3DSA:3.10.450.50 3 128 1.1E-22 T 28-03-2018 CIG75_RS17695 b98d44fd48e47f31b3176178539f1114 128 Pfam PF13474 SnoaL-like domain 13 126 1.5E-14 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CIG75_RS17695 b98d44fd48e47f31b3176178539f1114 128 SUPERFAMILY SSF54427 7 125 1.17E-24 T 28-03-2018 IPR032710 NTF2-like domain CIG75_RS00360 e59ab6cd800359b6841a3e934d6f5114 366 PIRSF PIRSF006641 1 366 1.4E-162 T 28-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 CIG75_RS00360 e59ab6cd800359b6841a3e934d6f5114 366 SUPERFAMILY SSF81271 282 363 8.07E-37 T 28-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CIG75_RS00360 e59ab6cd800359b6841a3e934d6f5114 366 Gene3D G3DSA:3.10.20.30 266 365 4.3E-48 T 28-03-2018 IPR012675 Beta-grasp domain CIG75_RS00360 e59ab6cd800359b6841a3e934d6f5114 366 Gene3D G3DSA:3.40.50.300 1 80 1.3E-8 T 28-03-2018 CIG75_RS00360 e59ab6cd800359b6841a3e934d6f5114 366 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 366 2.8E-159 T 28-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 CIG75_RS00360 e59ab6cd800359b6841a3e934d6f5114 366 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 366 46.057 T 28-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 CIG75_RS00360 e59ab6cd800359b6841a3e934d6f5114 366 Gene3D G3DSA:1.10.150.300 110 200 1.6E-29 T 28-03-2018 IPR023192 TGS-like domain Reactome: R-HSA-114608 CIG75_RS00360 e59ab6cd800359b6841a3e934d6f5114 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 7.4E-37 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CIG75_RS00360 e59ab6cd800359b6841a3e934d6f5114 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 7.4E-37 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CIG75_RS00360 e59ab6cd800359b6841a3e934d6f5114 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 7.4E-37 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CIG75_RS00360 e59ab6cd800359b6841a3e934d6f5114 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 7.4E-37 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CIG75_RS00360 e59ab6cd800359b6841a3e934d6f5114 366 Pfam PF01926 50S ribosome-binding GTPase 5 115 7.6E-24 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CIG75_RS00360 e59ab6cd800359b6841a3e934d6f5114 366 SUPERFAMILY SSF52540 3 304 1.03E-89 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS00360 e59ab6cd800359b6841a3e934d6f5114 366 Pfam PF06071 Protein of unknown function (DUF933) 282 365 4.1E-41 T 28-03-2018 IPR013029 Domain of unknown function DUF933 Reactome: R-HSA-114608 CIG75_RS05490 a196d2b49ffcafbf6851c27916f0268d 116 SUPERFAMILY SSF158622 1 106 5.76E-26 T 28-03-2018 IPR023378 YheA/YmcA-like domain CIG75_RS05490 a196d2b49ffcafbf6851c27916f0268d 116 Gene3D G3DSA:1.20.1500.10 2 107 1.0E-23 T 28-03-2018 IPR023378 YheA/YmcA-like domain CIG75_RS05490 a196d2b49ffcafbf6851c27916f0268d 116 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 4 106 2.7E-23 T 28-03-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA CIG75_RS10865 c7324ab471a77905e16ba31699936ef4 399 Hamap MF_01113 DNA polymerase IV [dinB]. 1 349 28.422 T 28-03-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 CIG75_RS10865 c7324ab471a77905e16ba31699936ef4 399 Gene3D G3DSA:3.30.1490.100 240 351 2.5E-24 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CIG75_RS10865 c7324ab471a77905e16ba31699936ef4 399 Gene3D G3DSA:1.10.150.20 166 239 1.0E-19 T 28-03-2018 CIG75_RS10865 c7324ab471a77905e16ba31699936ef4 399 Pfam PF00817 impB/mucB/samB family 1 146 8.5E-44 T 28-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CIG75_RS10865 c7324ab471a77905e16ba31699936ef4 399 SUPERFAMILY SSF56672 1 230 8.18E-69 T 28-03-2018 CIG75_RS10865 c7324ab471a77905e16ba31699936ef4 399 SUPERFAMILY SSF100879 239 337 1.61E-19 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CIG75_RS10865 c7324ab471a77905e16ba31699936ef4 399 Gene3D G3DSA:3.30.70.270 107 165 5.7E-10 T 28-03-2018 CIG75_RS10865 c7324ab471a77905e16ba31699936ef4 399 Gene3D G3DSA:3.30.70.270 34 106 6.7E-20 T 28-03-2018 CIG75_RS10865 c7324ab471a77905e16ba31699936ef4 399 Pfam PF11799 impB/mucB/samB family C-terminal domain 236 346 3.7E-19 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CIG75_RS17040 052934b6a31671c29cee02a4c5f7060f 156 Pfam PF01668 SmpB protein 11 151 1.0E-61 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 CIG75_RS17040 052934b6a31671c29cee02a4c5f7060f 156 SUPERFAMILY SSF74982 5 133 1.16E-52 T 28-03-2018 IPR023620 Small protein B CIG75_RS17040 052934b6a31671c29cee02a4c5f7060f 156 Gene3D G3DSA:2.40.280.10 10 128 8.3E-50 T 28-03-2018 IPR023620 Small protein B CIG75_RS17040 052934b6a31671c29cee02a4c5f7060f 156 TIGRFAM TIGR00086 smpB: SsrA-binding protein 10 150 9.3E-58 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 CIG75_RS17040 052934b6a31671c29cee02a4c5f7060f 156 ProSitePatterns PS01317 SsrA-binding protein. 28 40 - T 28-03-2018 IPR020081 SsrA-binding protein, conserved site CIG75_RS17040 052934b6a31671c29cee02a4c5f7060f 156 Hamap MF_00023 SsrA-binding protein [smpB]. 1 156 74.48 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 CIG75_RS17040 052934b6a31671c29cee02a4c5f7060f 156 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 10 133 7.0E-51 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 CIG75_RS05555 cc8888ea7dc51bc8ad81f5c2e72854a1 319 Gene3D G3DSA:3.40.50.450 179 300 5.3E-20 T 28-03-2018 CIG75_RS05555 cc8888ea7dc51bc8ad81f5c2e72854a1 319 SUPERFAMILY SSF53784 2 313 1.2E-114 T 28-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CIG75_RS05555 cc8888ea7dc51bc8ad81f5c2e72854a1 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 158 174 1.3E-86 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CIG75_RS05555 cc8888ea7dc51bc8ad81f5c2e72854a1 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 212 224 1.3E-86 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CIG75_RS05555 cc8888ea7dc51bc8ad81f5c2e72854a1 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 239 261 1.3E-86 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CIG75_RS05555 cc8888ea7dc51bc8ad81f5c2e72854a1 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 93 109 1.3E-86 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CIG75_RS05555 cc8888ea7dc51bc8ad81f5c2e72854a1 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 120 137 1.3E-86 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CIG75_RS05555 cc8888ea7dc51bc8ad81f5c2e72854a1 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 6 25 1.3E-86 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CIG75_RS05555 cc8888ea7dc51bc8ad81f5c2e72854a1 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 31 44 1.3E-86 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CIG75_RS05555 cc8888ea7dc51bc8ad81f5c2e72854a1 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 138 156 1.3E-86 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CIG75_RS05555 cc8888ea7dc51bc8ad81f5c2e72854a1 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 176 193 1.3E-86 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CIG75_RS05555 cc8888ea7dc51bc8ad81f5c2e72854a1 319 PIRSF PIRSF000532 1 318 2.5E-116 T 28-03-2018 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 CIG75_RS05555 cc8888ea7dc51bc8ad81f5c2e72854a1 319 Hamap MF_00339 ATP-dependent 6-phosphofructokinase [pfkA]. 1 318 46.269 T 28-03-2018 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 CIG75_RS05555 cc8888ea7dc51bc8ad81f5c2e72854a1 319 Pfam PF00365 Phosphofructokinase 3 275 6.2E-110 T 28-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CIG75_RS05555 cc8888ea7dc51bc8ad81f5c2e72854a1 319 ProSitePatterns PS00433 Phosphofructokinase signature. 243 261 - T 28-03-2018 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CIG75_RS05555 cc8888ea7dc51bc8ad81f5c2e72854a1 319 Gene3D G3DSA:3.40.50.450 1 178 4.3E-71 T 28-03-2018 CIG75_RS05555 cc8888ea7dc51bc8ad81f5c2e72854a1 319 TIGRFAM TIGR02482 PFKA_ATP: 6-phosphofructokinase 3 299 5.8E-127 T 28-03-2018 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 CIG75_RS17140 9e2a0047eedb95c7b6ab3565fb19d8ca 706 SMART SM00248 421 450 950.0 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 CIG75_RS17140 9e2a0047eedb95c7b6ab3565fb19d8ca 706 SMART SM00248 355 384 250.0 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 CIG75_RS17140 9e2a0047eedb95c7b6ab3565fb19d8ca 706 SMART SM00248 177 206 150.0 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 CIG75_RS17140 9e2a0047eedb95c7b6ab3565fb19d8ca 706 SMART SM00248 591 620 1.9 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 CIG75_RS17140 9e2a0047eedb95c7b6ab3565fb19d8ca 706 SMART SM00248 531 560 200.0 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 CIG75_RS17140 9e2a0047eedb95c7b6ab3565fb19d8ca 706 SMART SM00248 470 499 0.45 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 CIG75_RS17140 9e2a0047eedb95c7b6ab3565fb19d8ca 706 SMART SM00248 624 653 1.3 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 CIG75_RS17140 9e2a0047eedb95c7b6ab3565fb19d8ca 706 SMART SM00248 209 238 25.0 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 CIG75_RS17140 9e2a0047eedb95c7b6ab3565fb19d8ca 706 SMART SM00248 277 306 3.2E-4 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 CIG75_RS17140 9e2a0047eedb95c7b6ab3565fb19d8ca 706 SMART SM00248 321 350 13.0 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 CIG75_RS17140 9e2a0047eedb95c7b6ab3565fb19d8ca 706 SMART SM00248 243 272 37.0 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 CIG75_RS17140 9e2a0047eedb95c7b6ab3565fb19d8ca 706 SMART SM00248 388 417 2.1E-4 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 CIG75_RS17140 9e2a0047eedb95c7b6ab3565fb19d8ca 706 SMART SM00248 657 686 0.015 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 CIG75_RS17140 9e2a0047eedb95c7b6ab3565fb19d8ca 706 SUPERFAMILY SSF48403 467 683 9.02E-31 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain CIG75_RS17140 9e2a0047eedb95c7b6ab3565fb19d8ca 706 SUPERFAMILY SSF55383 87 170 1.83E-22 T 28-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CIG75_RS17140 9e2a0047eedb95c7b6ab3565fb19d8ca 706 Gene3D G3DSA:1.25.40.20 179 312 1.2E-24 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain CIG75_RS17140 9e2a0047eedb95c7b6ab3565fb19d8ca 706 SUPERFAMILY SSF48403 181 443 6.8E-45 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain CIG75_RS17140 9e2a0047eedb95c7b6ab3565fb19d8ca 706 Gene3D G3DSA:1.25.40.20 574 634 3.8E-10 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain CIG75_RS17140 9e2a0047eedb95c7b6ab3565fb19d8ca 706 Gene3D G3DSA:3.30.457.10 31 94 1.1E-6 T 28-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CIG75_RS17140 9e2a0047eedb95c7b6ab3565fb19d8ca 706 Gene3D G3DSA:3.30.457.10 95 155 3.3E-20 T 28-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CIG75_RS17140 9e2a0047eedb95c7b6ab3565fb19d8ca 706 Gene3D G3DSA:3.30.457.10 156 178 1.2E-5 T 28-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CIG75_RS17140 9e2a0047eedb95c7b6ab3565fb19d8ca 706 Pfam PF07833 Copper amine oxidase N-terminal domain 58 108 2.8E-6 T 28-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CIG75_RS17140 9e2a0047eedb95c7b6ab3565fb19d8ca 706 Pfam PF07833 Copper amine oxidase N-terminal domain 84 175 6.1E-24 T 28-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CIG75_RS17140 9e2a0047eedb95c7b6ab3565fb19d8ca 706 Gene3D G3DSA:1.25.40.20 635 699 1.5E-14 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain CIG75_RS17140 9e2a0047eedb95c7b6ab3565fb19d8ca 706 Gene3D G3DSA:1.25.40.20 397 460 4.6E-12 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain CIG75_RS17140 9e2a0047eedb95c7b6ab3565fb19d8ca 706 Gene3D G3DSA:1.25.40.20 313 396 2.1E-18 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain CIG75_RS17140 9e2a0047eedb95c7b6ab3565fb19d8ca 706 Gene3D G3DSA:1.25.40.20 461 573 5.4E-11 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain CIG75_RS17140 9e2a0047eedb95c7b6ab3565fb19d8ca 706 Pfam PF12796 Ankyrin repeats (3 copies) 475 558 1.9E-6 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain CIG75_RS17140 9e2a0047eedb95c7b6ab3565fb19d8ca 706 Pfam PF12796 Ankyrin repeats (3 copies) 598 686 1.6E-12 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain CIG75_RS17140 9e2a0047eedb95c7b6ab3565fb19d8ca 706 Pfam PF12796 Ankyrin repeats (3 copies) 215 306 9.8E-10 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain CIG75_RS17140 9e2a0047eedb95c7b6ab3565fb19d8ca 706 Pfam PF12796 Ankyrin repeats (3 copies) 326 418 6.5E-14 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain CIG75_RS01045 e45ae5fbe0574512afe018165c280e51 283 SUPERFAMILY SSF52540 4 234 1.66E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS01045 e45ae5fbe0574512afe018165c280e51 283 Gene3D G3DSA:3.40.50.300 1 243 4.0E-64 T 28-03-2018 CIG75_RS01045 e45ae5fbe0574512afe018165c280e51 283 SMART SM00382 31 218 2.3E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS01045 e45ae5fbe0574512afe018165c280e51 283 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS01045 e45ae5fbe0574512afe018165c280e51 283 Pfam PF00005 ABC transporter 22 170 2.8E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS02635 660ede52436f4bf2a4ad1c53b5501cc6 917 SUPERFAMILY SSF51556 539 643 3.74E-16 T 28-03-2018 IPR032466 Metal-dependent hydrolase CIG75_RS02635 660ede52436f4bf2a4ad1c53b5501cc6 917 SUPERFAMILY SSF51556 786 876 3.74E-16 T 28-03-2018 IPR032466 Metal-dependent hydrolase CIG75_RS02635 660ede52436f4bf2a4ad1c53b5501cc6 917 Gene3D G3DSA:3.20.20.140 157 895 1.3E-38 T 28-03-2018 CIG75_RS02635 660ede52436f4bf2a4ad1c53b5501cc6 917 Pfam PF00962 Adenosine/AMP deaminase 790 859 1.4E-4 T 28-03-2018 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 CIG75_RS18100 e78d1fb69a86d177db4937bc0b015d7d 298 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 107 193 6.5E-6 T 28-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CIG75_RS18100 e78d1fb69a86d177db4937bc0b015d7d 298 Gene3D G3DSA:1.10.1040.10 195 290 3.0E-22 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CIG75_RS18100 e78d1fb69a86d177db4937bc0b015d7d 298 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 196 280 1.1E-19 T 28-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CIG75_RS18100 e78d1fb69a86d177db4937bc0b015d7d 298 Gene3D G3DSA:3.40.50.720 31 194 1.0E-15 T 28-03-2018 CIG75_RS18100 e78d1fb69a86d177db4937bc0b015d7d 298 SUPERFAMILY SSF48179 192 283 4.34E-22 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CIG75_RS18100 e78d1fb69a86d177db4937bc0b015d7d 298 SUPERFAMILY SSF51735 32 193 2.68E-14 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS09260 4ebc5c141d9b2ea7192fd5f3228fc252 334 SUPERFAMILY SSF47413 3 60 1.35E-19 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CIG75_RS09260 4ebc5c141d9b2ea7192fd5f3228fc252 334 Gene3D G3DSA:1.10.260.40 4 60 1.8E-25 T 28-03-2018 CIG75_RS09260 4ebc5c141d9b2ea7192fd5f3228fc252 334 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 4 14 6.2E-7 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CIG75_RS09260 4ebc5c141d9b2ea7192fd5f3228fc252 334 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 14 24 6.2E-7 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CIG75_RS09260 4ebc5c141d9b2ea7192fd5f3228fc252 334 SUPERFAMILY SSF53822 61 332 1.03E-73 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CIG75_RS09260 4ebc5c141d9b2ea7192fd5f3228fc252 334 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 8.6E-21 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CIG75_RS09260 4ebc5c141d9b2ea7192fd5f3228fc252 334 SMART SM00354 2 72 1.7E-38 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CIG75_RS09260 4ebc5c141d9b2ea7192fd5f3228fc252 334 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 28-03-2018 CIG75_RS09260 4ebc5c141d9b2ea7192fd5f3228fc252 334 Pfam PF13377 Periplasmic binding protein-like domain 170 331 6.4E-30 T 28-03-2018 CIG75_RS09260 4ebc5c141d9b2ea7192fd5f3228fc252 334 Gene3D G3DSA:3.40.50.2300 168 334 2.3E-43 T 28-03-2018 CIG75_RS09260 4ebc5c141d9b2ea7192fd5f3228fc252 334 Gene3D G3DSA:3.40.50.2300 61 167 4.4E-27 T 28-03-2018 CIG75_RS01225 9d14517cb50a8c13750e0152aee7a416 633 Gene3D G3DSA:3.90.550.10 271 465 9.9E-22 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CIG75_RS01225 9d14517cb50a8c13750e0152aee7a416 633 Gene3D G3DSA:1.25.40.10 466 507 8.0E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS01225 9d14517cb50a8c13750e0152aee7a416 633 Gene3D G3DSA:3.90.550.10 4 269 9.8E-19 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CIG75_RS01225 9d14517cb50a8c13750e0152aee7a416 633 SUPERFAMILY SSF48452 459 613 5.88E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS01225 9d14517cb50a8c13750e0152aee7a416 633 Gene3D G3DSA:1.25.40.10 550 632 4.6E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS01225 9d14517cb50a8c13750e0152aee7a416 633 Gene3D G3DSA:1.25.40.10 508 549 3.9E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS01225 9d14517cb50a8c13750e0152aee7a416 633 Pfam PF00535 Glycosyl transferase family 2 274 358 1.2E-16 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CIG75_RS01225 9d14517cb50a8c13750e0152aee7a416 633 SUPERFAMILY SSF53448 3 151 3.62E-19 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CIG75_RS01225 9d14517cb50a8c13750e0152aee7a416 633 SUPERFAMILY SSF53448 184 253 3.62E-19 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CIG75_RS01225 9d14517cb50a8c13750e0152aee7a416 633 SUPERFAMILY SSF53448 272 418 1.29E-22 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CIG75_RS07550 283626beded057e28a9b45aa66b735b5 197 SUPERFAMILY SSF53955 72 195 1.5E-48 T 28-03-2018 IPR023346 Lysozyme-like domain CIG75_RS07550 283626beded057e28a9b45aa66b735b5 197 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 96 124 - T 28-03-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 CIG75_RS07550 283626beded057e28a9b45aa66b735b5 197 Gene3D G3DSA:1.10.530.10 29 197 4.9E-49 T 28-03-2018 CIG75_RS07550 283626beded057e28a9b45aa66b735b5 197 Pfam PF01464 Transglycosylase SLT domain 78 178 1.1E-30 T 28-03-2018 IPR008258 Transglycosylase SLT domain 1 CIG75_RS11965 75a46d68efa2c9ac0b9dd23b97c8a4d7 677 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 59 78 3.1E-56 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CIG75_RS11965 75a46d68efa2c9ac0b9dd23b97c8a4d7 677 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 140 158 3.1E-56 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CIG75_RS11965 75a46d68efa2c9ac0b9dd23b97c8a4d7 677 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 221 235 3.1E-56 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CIG75_RS11965 75a46d68efa2c9ac0b9dd23b97c8a4d7 677 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 121 137 3.1E-56 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CIG75_RS11965 75a46d68efa2c9ac0b9dd23b97c8a4d7 677 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 22 35 3.1E-56 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CIG75_RS11965 75a46d68efa2c9ac0b9dd23b97c8a4d7 677 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 170 187 3.1E-56 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CIG75_RS11965 75a46d68efa2c9ac0b9dd23b97c8a4d7 677 TIGRFAM TIGR01398 FlhA: flagellar biosynthesis protein FlhA 4 675 5.9E-275 T 28-03-2018 IPR006301 Flagellar biosynthesis protein FlhA GO:0016021|GO:0044780 CIG75_RS11965 75a46d68efa2c9ac0b9dd23b97c8a4d7 677 PIRSF PIRSF005419 1 677 3.9E-260 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CIG75_RS11965 75a46d68efa2c9ac0b9dd23b97c8a4d7 677 Pfam PF00771 FHIPEP family 15 667 1.4E-277 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CIG75_RS11915 46471513eb827cd70a3f0fe3cef77a2d 476 Gene3D G3DSA:2.160.20.70 203 313 4.6E-9 T 28-03-2018 CIG75_RS11915 46471513eb827cd70a3f0fe3cef77a2d 476 Pfam PF03961 Flagellar Assembly Protein A 23 470 9.1E-115 T 28-03-2018 IPR005646 Flagellar assembly protein A CIG75_RS19740 c863299001e22a541e3d21604d8fa95c 102 Gene3D G3DSA:3.30.70.600 3 102 1.7E-37 T 28-03-2018 IPR027486 Ribosomal protein S10 domain CIG75_RS19740 c863299001e22a541e3d21604d8fa95c 102 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 28-03-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CIG75_RS19740 c863299001e22a541e3d21604d8fa95c 102 SMART SM01403 7 101 2.1E-59 T 28-03-2018 IPR027486 Ribosomal protein S10 domain CIG75_RS19740 c863299001e22a541e3d21604d8fa95c 102 Pfam PF00338 Ribosomal protein S10p/S20e 7 101 1.4E-36 T 28-03-2018 IPR027486 Ribosomal protein S10 domain CIG75_RS19740 c863299001e22a541e3d21604d8fa95c 102 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 9.4E-47 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CIG75_RS19740 c863299001e22a541e3d21604d8fa95c 102 SUPERFAMILY SSF54999 5 102 3.27E-39 T 28-03-2018 IPR027486 Ribosomal protein S10 domain CIG75_RS19740 c863299001e22a541e3d21604d8fa95c 102 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 3.6E-21 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CIG75_RS19740 c863299001e22a541e3d21604d8fa95c 102 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 3.6E-21 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CIG75_RS19740 c863299001e22a541e3d21604d8fa95c 102 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 3.6E-21 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CIG75_RS19740 c863299001e22a541e3d21604d8fa95c 102 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 28.431 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CIG75_RS20075 2147887cdb4bc61fef267203d176dad4 158 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 85 157 1.3E-25 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CIG75_RS20075 2147887cdb4bc61fef267203d176dad4 158 SUPERFAMILY SSF54534 86 157 3.92E-20 T 28-03-2018 CIG75_RS20075 2147887cdb4bc61fef267203d176dad4 158 PIRSF PIRSF006092 1 158 7.2E-47 T 28-03-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 CIG75_RS20075 2147887cdb4bc61fef267203d176dad4 158 Gene3D G3DSA:1.10.287.180 5 77 8.4E-29 T 28-03-2018 CIG75_RS20075 2147887cdb4bc61fef267203d176dad4 158 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 8 157 3.4E-51 T 28-03-2018 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 CIG75_RS20075 2147887cdb4bc61fef267203d176dad4 158 SUPERFAMILY SSF46557 5 77 1.83E-24 T 28-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 CIG75_RS20075 2147887cdb4bc61fef267203d176dad4 158 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 122 138 - T 28-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 CIG75_RS20075 2147887cdb4bc61fef267203d176dad4 158 Hamap MF_00105 Transcription elongation factor GreA [greA]. 4 157 29.211 T 28-03-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 CIG75_RS20075 2147887cdb4bc61fef267203d176dad4 158 Pfam PF03449 Transcription elongation factor, N-terminal 7 76 9.9E-28 T 28-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 CIG75_RS20075 2147887cdb4bc61fef267203d176dad4 158 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 19 50 - T 28-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 CIG75_RS20075 2147887cdb4bc61fef267203d176dad4 158 Gene3D G3DSA:3.10.50.30 78 157 2.1E-25 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CIG75_RS04540 2df63e37e87f229efe4a6b0b96105d40 131 Pfam PF00293 NUDIX domain 5 121 2.3E-18 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CIG75_RS04540 2df63e37e87f229efe4a6b0b96105d40 131 Gene3D G3DSA:3.90.79.10 1 131 7.6E-29 T 28-03-2018 CIG75_RS04540 2df63e37e87f229efe4a6b0b96105d40 131 PRINTS PR00502 NUDIX hydrolase family signature 42 57 4.0E-6 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CIG75_RS04540 2df63e37e87f229efe4a6b0b96105d40 131 PRINTS PR00502 NUDIX hydrolase family signature 28 42 4.0E-6 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CIG75_RS04540 2df63e37e87f229efe4a6b0b96105d40 131 SUPERFAMILY SSF55811 5 127 1.29E-29 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CIG75_RS04540 2df63e37e87f229efe4a6b0b96105d40 131 ProSitePatterns PS00893 Nudix box signature. 33 54 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CIG75_RS16800 db0fe512fc756b1975d1422e1767acf3 395 SUPERFAMILY SSF50621 240 393 5.44E-36 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CIG75_RS16800 db0fe512fc756b1975d1422e1767acf3 395 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 32 274 2.8E-31 T 28-03-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 CIG75_RS16800 db0fe512fc756b1975d1422e1767acf3 395 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 214 231 - T 28-03-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site CIG75_RS16800 db0fe512fc756b1975d1422e1767acf3 395 Gene3D G3DSA:3.20.20.10 25 263 1.2E-47 T 28-03-2018 IPR029066 PLP-binding barrel CIG75_RS16800 db0fe512fc756b1975d1422e1767acf3 395 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 156 372 1.2E-15 T 28-03-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 CIG75_RS16800 db0fe512fc756b1975d1422e1767acf3 395 Gene3D G3DSA:2.40.37.10 264 395 2.7E-34 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CIG75_RS16800 db0fe512fc756b1975d1422e1767acf3 395 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 48 66 1.9E-7 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CIG75_RS16800 db0fe512fc756b1975d1422e1767acf3 395 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 179 192 1.9E-7 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CIG75_RS16800 db0fe512fc756b1975d1422e1767acf3 395 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 68 80 1.9E-7 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CIG75_RS16800 db0fe512fc756b1975d1422e1767acf3 395 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 264 283 1.9E-7 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CIG75_RS16800 db0fe512fc756b1975d1422e1767acf3 395 PRINTS PR01182 Ornithine decarboxylase signature 46 73 7.7E-7 T 28-03-2018 IPR002433 Ornithine decarboxylase GO:0006596 CIG75_RS16800 db0fe512fc756b1975d1422e1767acf3 395 PRINTS PR01182 Ornithine decarboxylase signature 359 372 7.7E-7 T 28-03-2018 IPR002433 Ornithine decarboxylase GO:0006596 CIG75_RS16800 db0fe512fc756b1975d1422e1767acf3 395 PRINTS PR01182 Ornithine decarboxylase signature 89 113 7.7E-7 T 28-03-2018 IPR002433 Ornithine decarboxylase GO:0006596 CIG75_RS16800 db0fe512fc756b1975d1422e1767acf3 395 SUPERFAMILY SSF51419 26 277 3.4E-58 T 28-03-2018 IPR029066 PLP-binding barrel CIG75_RS08515 3e4e2860cbc4ab940b5f4d415f6513e9 320 Gene3D G3DSA:3.40.50.720 1 146 1.1E-33 T 28-03-2018 CIG75_RS08515 3e4e2860cbc4ab940b5f4d415f6513e9 320 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 6 123 2.4E-23 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CIG75_RS08515 3e4e2860cbc4ab940b5f4d415f6513e9 320 SUPERFAMILY SSF51735 4 156 1.67E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS08515 3e4e2860cbc4ab940b5f4d415f6513e9 320 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 138 196 1.6E-4 T 28-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 CIG75_RS08515 3e4e2860cbc4ab940b5f4d415f6513e9 320 Gene3D G3DSA:3.30.360.10 147 320 1.0E-18 T 28-03-2018 CIG75_RS08515 3e4e2860cbc4ab940b5f4d415f6513e9 320 SUPERFAMILY SSF55347 133 261 2.4E-12 T 28-03-2018 CIG75_RS12410 c0324dcc9a4a842599e64235b6da0b12 161 Pfam PF01467 Cytidylyltransferase-like 5 133 1.6E-21 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CIG75_RS12410 c0324dcc9a4a842599e64235b6da0b12 161 SUPERFAMILY SSF52374 1 156 1.04E-44 T 28-03-2018 CIG75_RS12410 c0324dcc9a4a842599e64235b6da0b12 161 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 2 158 35.502 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CIG75_RS12410 c0324dcc9a4a842599e64235b6da0b12 161 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 85 101 9.6E-52 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CIG75_RS12410 c0324dcc9a4a842599e64235b6da0b12 161 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 49 73 9.6E-52 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CIG75_RS12410 c0324dcc9a4a842599e64235b6da0b12 161 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 2 20 9.6E-52 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CIG75_RS12410 c0324dcc9a4a842599e64235b6da0b12 161 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 20 41 9.6E-52 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CIG75_RS12410 c0324dcc9a4a842599e64235b6da0b12 161 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 112 134 9.6E-52 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CIG75_RS12410 c0324dcc9a4a842599e64235b6da0b12 161 ProDom PD016147 LIGASE LYASE CITRATE PRO-3S-LYASE SYNTHETASE TRANSFERASE CYTIDYLTRANSFERASE-RELATED:CITRATE ACETATE:SH-CITRATE CITC PLASMID 11 111 0.009 T 28-03-2018 CIG75_RS12410 c0324dcc9a4a842599e64235b6da0b12 161 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 3 63 5.8E-19 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CIG75_RS12410 c0324dcc9a4a842599e64235b6da0b12 161 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 3 157 7.1E-59 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CIG75_RS12410 c0324dcc9a4a842599e64235b6da0b12 161 Gene3D G3DSA:3.40.50.620 1 158 4.3E-37 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CIG75_RS19815 fa588139ea972008d40ecca861346e64 200 Pfam PF08281 Sigma-70, region 4 148 190 2.5E-9 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS19815 fa588139ea972008d40ecca861346e64 200 PIRSF PIRSF002939 1 200 2.7E-109 T 28-03-2018 IPR016371 RNA polymerase sigma-H factor GO:0003677|GO:0006351|GO:0016987 CIG75_RS19815 fa588139ea972008d40ecca861346e64 200 TIGRFAM TIGR02859 spore_sigH: RNA polymerase sigma-H factor 1 195 6.5E-112 T 28-03-2018 IPR014218 RNA polymerase sigma-H type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS19815 fa588139ea972008d40ecca861346e64 200 Pfam PF04542 Sigma-70 region 2 21 90 1.9E-14 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS19815 fa588139ea972008d40ecca861346e64 200 Gene3D G3DSA:1.10.10.10 123 199 1.1E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS19815 fa588139ea972008d40ecca861346e64 200 ProSitePatterns PS00622 LuxR-type HTH domain signature. 162 189 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CIG75_RS19815 fa588139ea972008d40ecca861346e64 200 SUPERFAMILY SSF88946 4 90 5.23E-22 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS19815 fa588139ea972008d40ecca861346e64 200 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 16 194 2.9E-25 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS19815 fa588139ea972008d40ecca861346e64 200 Gene3D G3DSA:1.10.1740.10 1 101 1.2E-21 T 28-03-2018 CIG75_RS19815 fa588139ea972008d40ecca861346e64 200 SUPERFAMILY SSF88659 108 195 8.11E-11 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS19815 fa588139ea972008d40ecca861346e64 200 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 45 58 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS10890 eae6af6523022cb39912029d742fa726 396 PIRSF PIRSF001413 2 395 4.1E-170 T 28-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CIG75_RS10890 eae6af6523022cb39912029d742fa726 396 Gene3D G3DSA:3.40.50.1100 197 396 6.7E-40 T 28-03-2018 CIG75_RS10890 eae6af6523022cb39912029d742fa726 396 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 81 95 - T 28-03-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CIG75_RS10890 eae6af6523022cb39912029d742fa726 396 Gene3D G3DSA:3.40.50.1100 9 196 4.1E-43 T 28-03-2018 CIG75_RS10890 eae6af6523022cb39912029d742fa726 396 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 54 378 2.6E-45 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CIG75_RS10890 eae6af6523022cb39912029d742fa726 396 SUPERFAMILY SSF53686 3 390 4.58E-148 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CIG75_RS10890 eae6af6523022cb39912029d742fa726 396 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 2 391 53.822 T 28-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CIG75_RS10890 eae6af6523022cb39912029d742fa726 396 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 7 390 1.4E-197 T 28-03-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CIG75_RS14265 d14df55b53f688df5f0df45f13eb68b5 631 SUPERFAMILY SSF90123 45 362 2.22E-89 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CIG75_RS14265 d14df55b53f688df5f0df45f13eb68b5 631 SMART SM00382 403 595 3.5E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS14265 d14df55b53f688df5f0df45f13eb68b5 631 Gene3D G3DSA:3.40.50.300 368 619 2.0E-72 T 28-03-2018 CIG75_RS14265 d14df55b53f688df5f0df45f13eb68b5 631 SUPERFAMILY SSF52540 367 613 2.38E-88 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS14265 d14df55b53f688df5f0df45f13eb68b5 631 Gene3D G3DSA:1.20.1560.10 30 365 5.5E-92 T 28-03-2018 CIG75_RS14265 d14df55b53f688df5f0df45f13eb68b5 631 Pfam PF00005 ABC transporter 394 543 4.2E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS14265 d14df55b53f688df5f0df45f13eb68b5 631 Pfam PF00664 ABC transporter transmembrane region 59 332 4.3E-62 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CIG75_RS05930 f94ac6e09377cbfc0531b89827d75a2e 451 Gene3D G3DSA:3.30.420.10 140 334 4.7E-38 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CIG75_RS05930 f94ac6e09377cbfc0531b89827d75a2e 451 SUPERFAMILY SSF46689 36 122 5.2E-6 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CIG75_RS05930 f94ac6e09377cbfc0531b89827d75a2e 451 Pfam PF00665 Integrase core domain 150 267 2.5E-23 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CIG75_RS05930 f94ac6e09377cbfc0531b89827d75a2e 451 Pfam PF09299 Mu transposase, C-terminal 333 380 8.4E-9 T 28-03-2018 IPR015378 Transposase-like, Mu, C-terminal CIG75_RS05930 f94ac6e09377cbfc0531b89827d75a2e 451 Pfam PF13518 Helix-turn-helix domain 36 71 1.1E-6 T 28-03-2018 CIG75_RS05930 f94ac6e09377cbfc0531b89827d75a2e 451 SUPERFAMILY SSF53098 147 309 4.17E-29 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CIG75_RS05930 f94ac6e09377cbfc0531b89827d75a2e 451 Gene3D G3DSA:2.30.30.130 335 388 0.0029 T 28-03-2018 IPR015378 Transposase-like, Mu, C-terminal CIG75_RS05930 f94ac6e09377cbfc0531b89827d75a2e 451 Gene3D G3DSA:1.10.10.10 9 77 0.001 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS00630 f94ac6e09377cbfc0531b89827d75a2e 451 Gene3D G3DSA:3.30.420.10 140 334 4.7E-38 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CIG75_RS00630 f94ac6e09377cbfc0531b89827d75a2e 451 SUPERFAMILY SSF46689 36 122 5.2E-6 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CIG75_RS00630 f94ac6e09377cbfc0531b89827d75a2e 451 Pfam PF00665 Integrase core domain 150 267 2.5E-23 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CIG75_RS00630 f94ac6e09377cbfc0531b89827d75a2e 451 Pfam PF09299 Mu transposase, C-terminal 333 380 8.4E-9 T 28-03-2018 IPR015378 Transposase-like, Mu, C-terminal CIG75_RS00630 f94ac6e09377cbfc0531b89827d75a2e 451 Pfam PF13518 Helix-turn-helix domain 36 71 1.1E-6 T 28-03-2018 CIG75_RS00630 f94ac6e09377cbfc0531b89827d75a2e 451 SUPERFAMILY SSF53098 147 309 4.17E-29 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CIG75_RS00630 f94ac6e09377cbfc0531b89827d75a2e 451 Gene3D G3DSA:2.30.30.130 335 388 0.0029 T 28-03-2018 IPR015378 Transposase-like, Mu, C-terminal CIG75_RS00630 f94ac6e09377cbfc0531b89827d75a2e 451 Gene3D G3DSA:1.10.10.10 9 77 0.001 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS03895 f94ac6e09377cbfc0531b89827d75a2e 451 Gene3D G3DSA:3.30.420.10 140 334 4.7E-38 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CIG75_RS03895 f94ac6e09377cbfc0531b89827d75a2e 451 SUPERFAMILY SSF46689 36 122 5.2E-6 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CIG75_RS03895 f94ac6e09377cbfc0531b89827d75a2e 451 Pfam PF00665 Integrase core domain 150 267 2.5E-23 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CIG75_RS03895 f94ac6e09377cbfc0531b89827d75a2e 451 Pfam PF09299 Mu transposase, C-terminal 333 380 8.4E-9 T 28-03-2018 IPR015378 Transposase-like, Mu, C-terminal CIG75_RS03895 f94ac6e09377cbfc0531b89827d75a2e 451 Pfam PF13518 Helix-turn-helix domain 36 71 1.1E-6 T 28-03-2018 CIG75_RS03895 f94ac6e09377cbfc0531b89827d75a2e 451 SUPERFAMILY SSF53098 147 309 4.17E-29 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CIG75_RS03895 f94ac6e09377cbfc0531b89827d75a2e 451 Gene3D G3DSA:2.30.30.130 335 388 0.0029 T 28-03-2018 IPR015378 Transposase-like, Mu, C-terminal CIG75_RS03895 f94ac6e09377cbfc0531b89827d75a2e 451 Gene3D G3DSA:1.10.10.10 9 77 0.001 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS14210 f94ac6e09377cbfc0531b89827d75a2e 451 Gene3D G3DSA:3.30.420.10 140 334 4.7E-38 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CIG75_RS14210 f94ac6e09377cbfc0531b89827d75a2e 451 SUPERFAMILY SSF46689 36 122 5.2E-6 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CIG75_RS14210 f94ac6e09377cbfc0531b89827d75a2e 451 Pfam PF00665 Integrase core domain 150 267 2.5E-23 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CIG75_RS14210 f94ac6e09377cbfc0531b89827d75a2e 451 Pfam PF09299 Mu transposase, C-terminal 333 380 8.4E-9 T 28-03-2018 IPR015378 Transposase-like, Mu, C-terminal CIG75_RS14210 f94ac6e09377cbfc0531b89827d75a2e 451 Pfam PF13518 Helix-turn-helix domain 36 71 1.1E-6 T 28-03-2018 CIG75_RS14210 f94ac6e09377cbfc0531b89827d75a2e 451 SUPERFAMILY SSF53098 147 309 4.17E-29 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CIG75_RS14210 f94ac6e09377cbfc0531b89827d75a2e 451 Gene3D G3DSA:2.30.30.130 335 388 0.0029 T 28-03-2018 IPR015378 Transposase-like, Mu, C-terminal CIG75_RS14210 f94ac6e09377cbfc0531b89827d75a2e 451 Gene3D G3DSA:1.10.10.10 9 77 0.001 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS14315 f5109e8c6a5a08e33248dc7db8c93d5e 181 SUPERFAMILY SSF55729 12 180 7.09E-31 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CIG75_RS14315 f5109e8c6a5a08e33248dc7db8c93d5e 181 Pfam PF00583 Acetyltransferase (GNAT) family 64 153 2.5E-15 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CIG75_RS14315 f5109e8c6a5a08e33248dc7db8c93d5e 181 Gene3D G3DSA:3.40.630.30 2 181 2.0E-29 T 28-03-2018 CIG75_RS19300 8fb897be92ebafe6e6ae37eba1cb5225 149 Gene3D G3DSA:2.60.40.420 17 149 7.7E-23 T 28-03-2018 IPR008972 Cupredoxin CIG75_RS19300 8fb897be92ebafe6e6ae37eba1cb5225 149 SUPERFAMILY SSF49503 47 148 6.77E-21 T 28-03-2018 IPR008972 Cupredoxin CIG75_RS19300 8fb897be92ebafe6e6ae37eba1cb5225 149 Pfam PF13473 Cupredoxin-like domain 52 131 7.0E-8 T 28-03-2018 IPR028096 EfeO-type cupredoxin-like domain CIG75_RS15545 5ca82b76d4cd1d1c98480adbff220b61 406 Gene3D G3DSA:1.20.1250.20 1 196 5.6E-26 T 28-03-2018 CIG75_RS15545 5ca82b76d4cd1d1c98480adbff220b61 406 SUPERFAMILY SSF103473 20 404 1.44E-47 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS15545 5ca82b76d4cd1d1c98480adbff220b61 406 Pfam PF07690 Major Facilitator Superfamily 29 359 3.5E-31 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CIG75_RS15545 5ca82b76d4cd1d1c98480adbff220b61 406 Gene3D G3DSA:1.20.1250.20 197 405 1.4E-21 T 28-03-2018 CIG75_RS07615 de9ea17c2c85b3ca94a90ede7660dd98 217 SUPERFAMILY SSF46894 141 212 5.44E-22 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CIG75_RS07615 de9ea17c2c85b3ca94a90ede7660dd98 217 Gene3D G3DSA:1.10.10.10 136 212 7.9E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS07615 de9ea17c2c85b3ca94a90ede7660dd98 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 195 2.0E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CIG75_RS07615 de9ea17c2c85b3ca94a90ede7660dd98 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 183 2.0E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CIG75_RS07615 de9ea17c2c85b3ca94a90ede7660dd98 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 167 2.0E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CIG75_RS07615 de9ea17c2c85b3ca94a90ede7660dd98 217 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 207 7.8E-20 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CIG75_RS07615 de9ea17c2c85b3ca94a90ede7660dd98 217 ProSitePatterns PS00622 LuxR-type HTH domain signature. 167 194 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CIG75_RS07615 de9ea17c2c85b3ca94a90ede7660dd98 217 SMART SM00421 150 207 8.7E-25 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CIG75_RS07615 de9ea17c2c85b3ca94a90ede7660dd98 217 Gene3D G3DSA:3.40.50.2300 3 135 5.8E-36 T 28-03-2018 CIG75_RS07615 de9ea17c2c85b3ca94a90ede7660dd98 217 SMART SM00448 4 117 1.3E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CIG75_RS07615 de9ea17c2c85b3ca94a90ede7660dd98 217 Pfam PF00072 Response regulator receiver domain 6 115 1.4E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CIG75_RS07615 de9ea17c2c85b3ca94a90ede7660dd98 217 SUPERFAMILY SSF52172 3 132 1.99E-34 T 28-03-2018 IPR011006 CheY-like superfamily CIG75_RS14975 ecc133e93aff6f27e74efe54bb7e51cc 187 Pfam PF04116 Fatty acid hydroxylase superfamily 28 169 4.6E-17 T 28-03-2018 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0008610|GO:0016491|GO:0055114 CIG75_RS07840 8ab52817c07807813a29aed181e918e7 417 SMART SM00382 108 270 8.8E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS07840 8ab52817c07807813a29aed181e918e7 417 SMART SM00994 10 49 2.7E-24 T 28-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 CIG75_RS07840 8ab52817c07807813a29aed181e918e7 417 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 2 408 52.974 T 28-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 CIG75_RS07840 8ab52817c07807813a29aed181e918e7 417 SMART SM01086 310 404 2.6E-32 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CIG75_RS07840 8ab52817c07807813a29aed181e918e7 417 Gene3D G3DSA:3.40.50.300 53 308 5.5E-73 T 28-03-2018 CIG75_RS07840 8ab52817c07807813a29aed181e918e7 417 Pfam PF06689 ClpX C4-type zinc finger 12 48 7.8E-21 T 28-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 CIG75_RS07840 8ab52817c07807813a29aed181e918e7 417 SUPERFAMILY SSF52540 59 394 8.48E-77 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS07840 8ab52817c07807813a29aed181e918e7 417 SUPERFAMILY SSF57716 11 46 1.57E-11 T 28-03-2018 CIG75_RS07840 8ab52817c07807813a29aed181e918e7 417 Pfam PF07724 AAA domain (Cdc48 subfamily) 109 303 5.4E-50 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CIG75_RS07840 8ab52817c07807813a29aed181e918e7 417 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 310 388 3.1E-19 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CIG75_RS07840 8ab52817c07807813a29aed181e918e7 417 Gene3D G3DSA:1.10.8.60 310 401 3.7E-33 T 28-03-2018 CIG75_RS07840 8ab52817c07807813a29aed181e918e7 417 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 1 404 1.9E-208 T 28-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 CIG75_RS13055 e0c08c3a38eb9bc0a7c467229d66eb9e 326 Gene3D G3DSA:3.10.290.10 19 90 2.1E-17 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CIG75_RS13055 e0c08c3a38eb9bc0a7c467229d66eb9e 326 Gene3D G3DSA:3.30.2350.10 97 326 1.2E-71 T 28-03-2018 CIG75_RS13055 e0c08c3a38eb9bc0a7c467229d66eb9e 326 SUPERFAMILY SSF55174 33 119 3.7E-13 T 28-03-2018 CIG75_RS13055 e0c08c3a38eb9bc0a7c467229d66eb9e 326 SMART SM00363 33 97 4.1E-6 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CIG75_RS13055 e0c08c3a38eb9bc0a7c467229d66eb9e 326 Pfam PF01479 S4 domain 33 79 5.8E-8 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CIG75_RS13055 e0c08c3a38eb9bc0a7c467229d66eb9e 326 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 29 322 3.6E-99 T 28-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 CIG75_RS13055 e0c08c3a38eb9bc0a7c467229d66eb9e 326 Pfam PF00849 RNA pseudouridylate synthase 106 259 2.5E-35 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CIG75_RS13055 e0c08c3a38eb9bc0a7c467229d66eb9e 326 SUPERFAMILY SSF55120 94 323 4.11E-78 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CIG75_RS10015 0bd5b231293c9fed2ea18e775c0bfb6d 514 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS10015 0bd5b231293c9fed2ea18e775c0bfb6d 514 SMART SM00382 349 514 1.6E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS10015 0bd5b231293c9fed2ea18e775c0bfb6d 514 SMART SM00382 28 236 2.4E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS10015 0bd5b231293c9fed2ea18e775c0bfb6d 514 SUPERFAMILY SSF52540 6 244 2.03E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS10015 0bd5b231293c9fed2ea18e775c0bfb6d 514 Gene3D G3DSA:3.40.50.300 291 514 6.8E-42 T 28-03-2018 CIG75_RS10015 0bd5b231293c9fed2ea18e775c0bfb6d 514 Pfam PF12848 ABC transporter 230 313 7.7E-23 T 28-03-2018 IPR032781 ABC-transporter extension domain CIG75_RS10015 0bd5b231293c9fed2ea18e775c0bfb6d 514 SUPERFAMILY SSF52540 311 511 6.1E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS10015 0bd5b231293c9fed2ea18e775c0bfb6d 514 Pfam PF00005 ABC transporter 19 191 2.6E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS10015 0bd5b231293c9fed2ea18e775c0bfb6d 514 Pfam PF00005 ABC transporter 343 469 6.6E-19 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS10015 0bd5b231293c9fed2ea18e775c0bfb6d 514 Gene3D G3DSA:3.40.50.300 4 290 1.7E-52 T 28-03-2018 CIG75_RS16915 41563194bdba0b16510f9b80ddf63b41 267 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 9 215 1.7E-49 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CIG75_RS16915 41563194bdba0b16510f9b80ddf63b41 267 Gene3D G3DSA:3.40.1010.10 8 128 6.2E-35 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CIG75_RS16915 41563194bdba0b16510f9b80ddf63b41 267 Gene3D G3DSA:3.30.950.10 129 244 1.4E-28 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CIG75_RS16915 41563194bdba0b16510f9b80ddf63b41 267 TIGRFAM TIGR01465 cobM_cbiF: precorrin-4 C11-methyltransferase 10 260 4.1E-108 T 28-03-2018 IPR006362 Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase GO:0009236|GO:0046026 CIG75_RS16915 41563194bdba0b16510f9b80ddf63b41 267 SUPERFAMILY SSF53790 7 259 2.49E-71 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CIG75_RS16915 41563194bdba0b16510f9b80ddf63b41 267 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 13 27 - T 28-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CIG75_RS00850 445e3bc835d8c0221df7d96e8e0d99c5 223 Gene3D G3DSA:3.40.50.1360 1 136 2.2E-43 T 28-03-2018 CIG75_RS00850 445e3bc835d8c0221df7d96e8e0d99c5 223 SUPERFAMILY SSF100950 2 144 1.4E-43 T 28-03-2018 CIG75_RS00850 445e3bc835d8c0221df7d96e8e0d99c5 223 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 4 217 4.0E-83 T 28-03-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CIG75_RS00850 445e3bc835d8c0221df7d96e8e0d99c5 223 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 48 216 1.3E-65 T 28-03-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CIG75_RS00850 445e3bc835d8c0221df7d96e8e0d99c5 223 Gene3D G3DSA:3.30.70.260 137 200 1.2E-24 T 28-03-2018 CIG75_RS00850 445e3bc835d8c0221df7d96e8e0d99c5 223 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 1 220 32.044 T 28-03-2018 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CIG75_RS00850 445e3bc835d8c0221df7d96e8e0d99c5 223 SUPERFAMILY SSF75445 125 203 4.19E-23 T 28-03-2018 CIG75_RS06625 52de6cd8e64d88d58bc4e1b0d4a243de 1577 Gene3D G3DSA:3.40.50.980 503 659 2.9E-51 T 28-03-2018 CIG75_RS06625 52de6cd8e64d88d58bc4e1b0d4a243de 1577 SUPERFAMILY SSF52777 1294 1541 2.45E-40 T 28-03-2018 CIG75_RS06625 52de6cd8e64d88d58bc4e1b0d4a243de 1577 Gene3D G3DSA:3.30.559.10 23 254 5.6E-37 T 28-03-2018 CIG75_RS06625 52de6cd8e64d88d58bc4e1b0d4a243de 1577 SUPERFAMILY SSF52777 51 229 8.23E-45 T 28-03-2018 CIG75_RS06625 52de6cd8e64d88d58bc4e1b0d4a243de 1577 Gene3D G3DSA:3.40.50.980 660 824 1.3E-37 T 28-03-2018 CIG75_RS06625 52de6cd8e64d88d58bc4e1b0d4a243de 1577 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 1411 1565 6.5E-46 T 28-03-2018 IPR010060 Non-ribosomal peptide synthase CIG75_RS06625 52de6cd8e64d88d58bc4e1b0d4a243de 1577 Gene3D G3DSA:2.30.38.10 827 910 1.2E-23 T 28-03-2018 CIG75_RS06625 52de6cd8e64d88d58bc4e1b0d4a243de 1577 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1049 1064 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS06625 52de6cd8e64d88d58bc4e1b0d4a243de 1577 Pfam PF13193 AMP-binding enzyme C-terminal domain 925 1000 9.9E-15 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS06625 52de6cd8e64d88d58bc4e1b0d4a243de 1577 Pfam PF00501 AMP-binding enzyme 512 917 3.2E-107 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS06625 52de6cd8e64d88d58bc4e1b0d4a243de 1577 SUPERFAMILY SSF52777 235 481 3.67E-59 T 28-03-2018 CIG75_RS06625 52de6cd8e64d88d58bc4e1b0d4a243de 1577 SUPERFAMILY SSF52777 1108 1284 8.45E-43 T 28-03-2018 CIG75_RS06625 52de6cd8e64d88d58bc4e1b0d4a243de 1577 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 533 941 2.0E-139 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS06625 52de6cd8e64d88d58bc4e1b0d4a243de 1577 Gene3D G3DSA:3.30.559.10 1085 1294 8.9E-35 T 28-03-2018 CIG75_RS06625 52de6cd8e64d88d58bc4e1b0d4a243de 1577 Gene3D G3DSA:1.10.1200.10 1032 1084 6.4E-20 T 28-03-2018 CIG75_RS06625 52de6cd8e64d88d58bc4e1b0d4a243de 1577 SUPERFAMILY SSF47336 1018 1086 3.66E-17 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS06625 52de6cd8e64d88d58bc4e1b0d4a243de 1577 SMART SM00823 Phosphopantetheine attachment site 1025 1093 0.0039 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS06625 52de6cd8e64d88d58bc4e1b0d4a243de 1577 Pfam PF00550 Phosphopantetheine attachment site 1027 1086 7.3E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS06625 52de6cd8e64d88d58bc4e1b0d4a243de 1577 Gene3D G3DSA:3.30.300.30 912 1031 2.2E-37 T 28-03-2018 CIG75_RS06625 52de6cd8e64d88d58bc4e1b0d4a243de 1577 Pfam PF00668 Condensation domain 1104 1553 5.5E-94 T 28-03-2018 IPR001242 Condensation domain CIG75_RS06625 52de6cd8e64d88d58bc4e1b0d4a243de 1577 Pfam PF00668 Condensation domain 50 492 1.4E-108 T 28-03-2018 IPR001242 Condensation domain CIG75_RS06625 52de6cd8e64d88d58bc4e1b0d4a243de 1577 ProSitePatterns PS00455 Putative AMP-binding domain signature. 654 665 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS06625 52de6cd8e64d88d58bc4e1b0d4a243de 1577 SUPERFAMILY SSF56801 470 1037 1.44E-169 T 28-03-2018 CIG75_RS01660 b6b107b19916ec3f367b975aee58b873 249 Pfam PF06738 Putative threonine/serine exporter 10 248 2.4E-70 T 28-03-2018 IPR010619 Putative threonine/serine exporter CIG75_RS05905 7e0b1514c967e865f303d63b9edc8c6b 407 SUPERFAMILY SSF48452 123 321 3.6E-16 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS05905 7e0b1514c967e865f303d63b9edc8c6b 407 SMART SM00028 209 242 62.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS05905 7e0b1514c967e865f303d63b9edc8c6b 407 SMART SM00028 331 364 470.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS05905 7e0b1514c967e865f303d63b9edc8c6b 407 SMART SM00028 128 161 0.15 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS05905 7e0b1514c967e865f303d63b9edc8c6b 407 Gene3D G3DSA:1.25.40.10 45 171 1.4E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS05905 7e0b1514c967e865f303d63b9edc8c6b 407 Gene3D G3DSA:1.25.40.10 205 395 3.6E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS05905 7e0b1514c967e865f303d63b9edc8c6b 407 SUPERFAMILY SSF48452 310 393 9.48E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS05905 7e0b1514c967e865f303d63b9edc8c6b 407 SUPERFAMILY SSF47413 2 45 2.06E-6 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CIG75_RS05905 7e0b1514c967e865f303d63b9edc8c6b 407 Gene3D G3DSA:1.10.260.40 1 44 9.8E-9 T 28-03-2018 CIG75_RS05905 7e0b1514c967e865f303d63b9edc8c6b 407 Gene3D G3DSA:3.30.70.100 172 204 0.017 T 28-03-2018 CIG75_RS00205 cf2e2613518a266af423d959f212be83 369 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 369 99.371 T 28-03-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 CIG75_RS00205 cf2e2613518a266af423d959f212be83 369 ProSitePatterns PS00618 RecF protein signature 2. 309 327 - T 28-03-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 CIG75_RS00205 cf2e2613518a266af423d959f212be83 369 Gene3D G3DSA:3.40.50.300 1 368 2.0E-27 T 28-03-2018 CIG75_RS00205 cf2e2613518a266af423d959f212be83 369 SUPERFAMILY SSF52540 1 343 1.05E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS00205 cf2e2613518a266af423d959f212be83 369 ProSitePatterns PS00617 RecF protein signature 1. 117 137 - T 28-03-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 CIG75_RS00205 cf2e2613518a266af423d959f212be83 369 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 362 6.9E-16 T 28-03-2018 IPR003395 RecF/RecN/SMC, N-terminal CIG75_RS00205 cf2e2613518a266af423d959f212be83 369 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 1 362 1.7E-120 T 28-03-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 CIG75_RS08695 fee76508d19e1d552de9699ec037c9a2 115 SUPERFAMILY SSF52091 2 110 3.4E-30 T 28-03-2018 IPR002645 STAS domain CIG75_RS08695 fee76508d19e1d552de9699ec037c9a2 115 Pfam PF01740 STAS domain 10 108 9.5E-20 T 28-03-2018 IPR002645 STAS domain CIG75_RS08695 fee76508d19e1d552de9699ec037c9a2 115 Gene3D G3DSA:3.30.750.24 1 113 2.0E-21 T 28-03-2018 IPR002645 STAS domain CIG75_RS08695 fee76508d19e1d552de9699ec037c9a2 115 TIGRFAM TIGR02886 spore_II_AA: anti-sigma F factor antagonist 6 109 3.7E-43 T 28-03-2018 IPR014237 Anti-sigma F factor antagonist GO:0006355|GO:0030435|GO:0045152 CIG75_RS08695 fee76508d19e1d552de9699ec037c9a2 115 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 2 105 4.9E-34 T 28-03-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 CIG75_RS06715 63d1fe1fdc28f0563d3db0b7f19c16ff 1095 Gene3D G3DSA:3.40.50.980 633 795 1.0E-32 T 28-03-2018 CIG75_RS06715 63d1fe1fdc28f0563d3db0b7f19c16ff 1095 SUPERFAMILY SSF52777 208 448 3.22E-67 T 28-03-2018 CIG75_RS06715 63d1fe1fdc28f0563d3db0b7f19c16ff 1095 Pfam PF00550 Phosphopantetheine attachment site 997 1060 1.4E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS06715 63d1fe1fdc28f0563d3db0b7f19c16ff 1095 ProSitePatterns PS00455 Putative AMP-binding domain signature. 627 638 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS06715 63d1fe1fdc28f0563d3db0b7f19c16ff 1095 SUPERFAMILY SSF52777 23 200 7.0E-50 T 28-03-2018 CIG75_RS06715 63d1fe1fdc28f0563d3db0b7f19c16ff 1095 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 506 909 1.0E-136 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS06715 63d1fe1fdc28f0563d3db0b7f19c16ff 1095 SUPERFAMILY SSF56801 445 1008 4.06E-167 T 28-03-2018 CIG75_RS06715 63d1fe1fdc28f0563d3db0b7f19c16ff 1095 Gene3D G3DSA:2.30.38.10 796 875 4.2E-25 T 28-03-2018 CIG75_RS06715 63d1fe1fdc28f0563d3db0b7f19c16ff 1095 SUPERFAMILY SSF47336 987 1060 1.23E-20 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS06715 63d1fe1fdc28f0563d3db0b7f19c16ff 1095 Gene3D G3DSA:3.40.50.980 477 632 1.2E-49 T 28-03-2018 CIG75_RS06715 63d1fe1fdc28f0563d3db0b7f19c16ff 1095 SMART SM00823 Phosphopantetheine attachment site 995 1064 4.7E-4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS06715 63d1fe1fdc28f0563d3db0b7f19c16ff 1095 Pfam PF13193 AMP-binding enzyme C-terminal domain 893 967 6.8E-16 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS06715 63d1fe1fdc28f0563d3db0b7f19c16ff 1095 Gene3D G3DSA:1.10.1200.10 1001 1067 5.3E-22 T 28-03-2018 CIG75_RS06715 63d1fe1fdc28f0563d3db0b7f19c16ff 1095 Pfam PF00668 Condensation domain 22 462 4.5E-117 T 28-03-2018 IPR001242 Condensation domain CIG75_RS06715 63d1fe1fdc28f0563d3db0b7f19c16ff 1095 Pfam PF00501 AMP-binding enzyme 485 885 7.8E-104 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS06715 63d1fe1fdc28f0563d3db0b7f19c16ff 1095 Gene3D G3DSA:3.30.559.10 16 222 9.5E-43 T 28-03-2018 CIG75_RS06715 63d1fe1fdc28f0563d3db0b7f19c16ff 1095 Gene3D G3DSA:3.30.300.30 880 1000 3.0E-43 T 28-03-2018 CIG75_RS19585 b754d8f294f0f791ccf06ce329c6eb93 120 SUPERFAMILY SSF64263 2 120 3.53E-44 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS19585 b754d8f294f0f791ccf06ce329c6eb93 120 ProSitePatterns PS01167 Ribosomal protein L17 signature. 30 52 - T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS19585 b754d8f294f0f791ccf06ce329c6eb93 120 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 1 120 27.965 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS19585 b754d8f294f0f791ccf06ce329c6eb93 120 Gene3D G3DSA:3.90.1030.10 1 120 4.9E-47 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS19585 b754d8f294f0f791ccf06ce329c6eb93 120 Pfam PF01196 Ribosomal protein L17 16 120 1.2E-39 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS19585 b754d8f294f0f791ccf06ce329c6eb93 120 TIGRFAM TIGR00059 L17: ribosomal protein bL17 3 120 5.0E-45 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS02740 7b0f18153b1046210b3529e69fa9fffb 324 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 11 292 3.0E-52 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CIG75_RS02740 7b0f18153b1046210b3529e69fa9fffb 324 Gene3D G3DSA:3.40.50.1100 140 314 2.2E-40 T 28-03-2018 CIG75_RS02740 7b0f18153b1046210b3529e69fa9fffb 324 Gene3D G3DSA:3.40.50.1100 38 139 2.8E-20 T 28-03-2018 CIG75_RS02740 7b0f18153b1046210b3529e69fa9fffb 324 TIGRFAM TIGR03945 PLP_SbnA_fam: 2,3-diaminopropionate biosynthesis protein SbnA 9 309 1.1E-125 T 28-03-2018 IPR023927 2,3-diaminopropionate biosynthesis protein SbnA CIG75_RS02740 7b0f18153b1046210b3529e69fa9fffb 324 SUPERFAMILY SSF53686 5 312 4.06E-69 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CIG75_RS02225 3cbc7d0a61016b8d132710e7ae71be61 259 SUPERFAMILY SSF46894 191 257 6.8E-21 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CIG75_RS02225 3cbc7d0a61016b8d132710e7ae71be61 259 SMART SM00421 194 251 8.2E-25 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CIG75_RS02225 3cbc7d0a61016b8d132710e7ae71be61 259 Gene3D G3DSA:1.10.10.10 160 259 7.8E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS02225 3cbc7d0a61016b8d132710e7ae71be61 259 Pfam PF00196 Bacterial regulatory proteins, luxR family 196 250 1.1E-20 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CIG75_RS02225 3cbc7d0a61016b8d132710e7ae71be61 259 Gene3D G3DSA:3.40.50.2300 34 159 4.4E-33 T 28-03-2018 CIG75_RS02225 3cbc7d0a61016b8d132710e7ae71be61 259 Pfam PF00072 Response regulator receiver domain 38 149 3.8E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CIG75_RS02225 3cbc7d0a61016b8d132710e7ae71be61 259 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 227 239 9.1E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CIG75_RS02225 3cbc7d0a61016b8d132710e7ae71be61 259 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 211 227 9.1E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CIG75_RS02225 3cbc7d0a61016b8d132710e7ae71be61 259 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 197 211 9.1E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CIG75_RS02225 3cbc7d0a61016b8d132710e7ae71be61 259 SMART SM00448 35 148 2.1E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CIG75_RS02225 3cbc7d0a61016b8d132710e7ae71be61 259 SUPERFAMILY SSF52172 34 166 3.27E-33 T 28-03-2018 IPR011006 CheY-like superfamily CIG75_RS02225 3cbc7d0a61016b8d132710e7ae71be61 259 ProSitePatterns PS00622 LuxR-type HTH domain signature. 211 238 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CIG75_RS11065 56ef9e544e3af5a648631c75ce3c403d 1495 Gene3D G3DSA:3.40.366.10 670 840 3.8E-31 T 28-03-2018 CIG75_RS11065 56ef9e544e3af5a648631c75ce3c403d 1495 Gene3D G3DSA:3.40.366.10 511 669 1.0E-44 T 28-03-2018 CIG75_RS11065 56ef9e544e3af5a648631c75ce3c403d 1495 Gene3D G3DSA:3.40.47.10 1 256 3.8E-68 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS11065 56ef9e544e3af5a648631c75ce3c403d 1495 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 156 172 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CIG75_RS11065 56ef9e544e3af5a648631c75ce3c403d 1495 SUPERFAMILY SSF55048 692 738 3.66E-6 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CIG75_RS11065 56ef9e544e3af5a648631c75ce3c403d 1495 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 251 370 1.1E-41 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CIG75_RS11065 56ef9e544e3af5a648631c75ce3c403d 1495 SUPERFAMILY SSF53901 397 418 8.11E-78 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS11065 56ef9e544e3af5a648631c75ce3c403d 1495 SUPERFAMILY SSF53901 1 110 8.11E-78 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS11065 56ef9e544e3af5a648631c75ce3c403d 1495 SUPERFAMILY SSF53901 139 366 8.11E-78 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS11065 56ef9e544e3af5a648631c75ce3c403d 1495 Pfam PF00698 Acyl transferase domain 693 827 3.6E-10 T 28-03-2018 IPR014043 Acyl transferase CIG75_RS11065 56ef9e544e3af5a648631c75ce3c403d 1495 Pfam PF00698 Acyl transferase domain 516 645 1.1E-32 T 28-03-2018 IPR014043 Acyl transferase CIG75_RS11065 56ef9e544e3af5a648631c75ce3c403d 1495 SUPERFAMILY SSF51735 911 1120 2.13E-24 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS11065 56ef9e544e3af5a648631c75ce3c403d 1495 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1 243 4.9E-68 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CIG75_RS11065 56ef9e544e3af5a648631c75ce3c403d 1495 Gene3D G3DSA:3.40.47.10 258 420 1.6E-58 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS11065 56ef9e544e3af5a648631c75ce3c403d 1495 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1419 1434 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS11065 56ef9e544e3af5a648631c75ce3c403d 1495 SMART SM00825 Beta-ketoacyl synthase 1 422 1.1E-173 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CIG75_RS11065 56ef9e544e3af5a648631c75ce3c403d 1495 SMART SM00823 Phosphopantetheine attachment site 1392 1464 9.0E-10 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS11065 56ef9e544e3af5a648631c75ce3c403d 1495 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 373 484 8.0E-20 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS11065 56ef9e544e3af5a648631c75ce3c403d 1495 SUPERFAMILY SSF47336 1387 1460 7.33E-21 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS11065 56ef9e544e3af5a648631c75ce3c403d 1495 Pfam PF08659 KR domain 1134 1297 4.0E-31 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS11065 56ef9e544e3af5a648631c75ce3c403d 1495 Gene3D G3DSA:3.40.50.720 1126 1378 1.4E-27 T 28-03-2018 CIG75_RS11065 56ef9e544e3af5a648631c75ce3c403d 1495 SUPERFAMILY SSF52151 515 639 4.45E-65 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CIG75_RS11065 56ef9e544e3af5a648631c75ce3c403d 1495 SUPERFAMILY SSF52151 739 831 4.45E-65 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CIG75_RS11065 56ef9e544e3af5a648631c75ce3c403d 1495 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 518 841 3.2E-89 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CIG75_RS11065 56ef9e544e3af5a648631c75ce3c403d 1495 SUPERFAMILY SSF51735 1130 1354 5.87E-24 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS11065 56ef9e544e3af5a648631c75ce3c403d 1495 Gene3D G3DSA:1.10.1200.10 1382 1473 2.9E-22 T 28-03-2018 CIG75_RS11065 56ef9e544e3af5a648631c75ce3c403d 1495 Pfam PF00550 Phosphopantetheine attachment site 1397 1459 1.4E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS11065 56ef9e544e3af5a648631c75ce3c403d 1495 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1134 1300 2.3E-30 T 28-03-2018 CIG75_RS02835 64182a679646182a8c5aac91983367d0 361 SUPERFAMILY SSF47240 8 98 1.06E-5 T 28-03-2018 IPR009078 Ferritin-like superfamily CIG75_RS02835 64182a679646182a8c5aac91983367d0 361 Gene3D G3DSA:1.20.1260.10 3 115 1.5E-6 T 28-03-2018 IPR012347 Ferritin-related CIG75_RS02835 64182a679646182a8c5aac91983367d0 361 Pfam PF12902 Ferritin-like 14 240 2.2E-61 T 28-03-2018 CIG75_RS13760 0b728a74da05d380a83dfa483043fc6c 537 Gene3D G3DSA:3.40.50.300 1 283 3.7E-56 T 28-03-2018 CIG75_RS13760 0b728a74da05d380a83dfa483043fc6c 537 SUPERFAMILY SSF52540 296 525 1.67E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS13760 0b728a74da05d380a83dfa483043fc6c 537 Pfam PF12848 ABC transporter 224 305 9.0E-22 T 28-03-2018 IPR032781 ABC-transporter extension domain CIG75_RS13760 0b728a74da05d380a83dfa483043fc6c 537 Gene3D G3DSA:3.40.50.300 284 537 6.8E-41 T 28-03-2018 CIG75_RS13760 0b728a74da05d380a83dfa483043fc6c 537 Pfam PF00005 ABC transporter 18 184 9.5E-22 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS13760 0b728a74da05d380a83dfa483043fc6c 537 Pfam PF00005 ABC transporter 335 466 3.6E-16 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS13760 0b728a74da05d380a83dfa483043fc6c 537 SUPERFAMILY SSF52540 7 237 1.27E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS13760 0b728a74da05d380a83dfa483043fc6c 537 SMART SM00382 344 512 0.0025 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS13760 0b728a74da05d380a83dfa483043fc6c 537 SMART SM00382 26 238 1.4E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS20270 e63974d8263b31882c7fd3cd6f4f57aa 1181 SUPERFAMILY SSF52540 15 344 2.55E-81 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS20270 e63974d8263b31882c7fd3cd6f4f57aa 1181 SUPERFAMILY SSF141259 489 565 4.97E-24 T 28-03-2018 IPR003711 CarD-like/TRCF domain CIG75_RS20270 e63974d8263b31882c7fd3cd6f4f57aa 1181 Gene3D G3DSA:3.40.50.300 807 974 1.9E-25 T 28-03-2018 CIG75_RS20270 e63974d8263b31882c7fd3cd6f4f57aa 1181 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 46 1161 29.254 T 28-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 CIG75_RS20270 e63974d8263b31882c7fd3cd6f4f57aa 1181 SMART SM00490 844 928 1.1E-21 T 28-03-2018 IPR001650 Helicase, C-terminal CIG75_RS20270 e63974d8263b31882c7fd3cd6f4f57aa 1181 Pfam PF00271 Helicase conserved C-terminal domain 828 927 2.2E-16 T 28-03-2018 IPR001650 Helicase, C-terminal CIG75_RS20270 e63974d8263b31882c7fd3cd6f4f57aa 1181 SUPERFAMILY SSF52540 542 801 2.85E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS20270 e63974d8263b31882c7fd3cd6f4f57aa 1181 SMART SM00982 1023 1124 5.1E-34 T 28-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 CIG75_RS20270 e63974d8263b31882c7fd3cd6f4f57aa 1181 Pfam PF00270 DEAD/DEAH box helicase 623 780 7.4E-18 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CIG75_RS20270 e63974d8263b31882c7fd3cd6f4f57aa 1181 SMART SM00487 618 808 1.0E-33 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CIG75_RS20270 e63974d8263b31882c7fd3cd6f4f57aa 1181 SUPERFAMILY SSF143517 1012 1162 1.57E-33 T 28-03-2018 CIG75_RS20270 e63974d8263b31882c7fd3cd6f4f57aa 1181 Gene3D G3DSA:3.30.2060.10 141 216 4.6E-4 T 28-03-2018 CIG75_RS20270 e63974d8263b31882c7fd3cd6f4f57aa 1181 Pfam PF03461 TRCF domain 1024 1117 2.9E-25 T 28-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 CIG75_RS20270 e63974d8263b31882c7fd3cd6f4f57aa 1181 Pfam PF02559 CarD-like/TRCF domain 498 593 2.9E-30 T 28-03-2018 IPR003711 CarD-like/TRCF domain CIG75_RS20270 e63974d8263b31882c7fd3cd6f4f57aa 1181 SMART SM01058 497 594 5.8E-45 T 28-03-2018 IPR003711 CarD-like/TRCF domain CIG75_RS20270 e63974d8263b31882c7fd3cd6f4f57aa 1181 SUPERFAMILY SSF52540 378 483 7.35E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS20270 e63974d8263b31882c7fd3cd6f4f57aa 1181 SUPERFAMILY SSF52540 800 1008 1.27E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS20270 e63974d8263b31882c7fd3cd6f4f57aa 1181 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 157 1097 0.0 T 28-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 CIG75_RS20270 e63974d8263b31882c7fd3cd6f4f57aa 1181 Gene3D G3DSA:3.40.50.300 400 789 9.9E-38 T 28-03-2018 CIG75_RS10710 3b5f36b9174908d61c6d81d387ea0fec 1506 SUPERFAMILY SSF47336 980 1053 1.22E-21 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10710 3b5f36b9174908d61c6d81d387ea0fec 1506 Gene3D G3DSA:3.40.50.980 472 628 4.4E-54 T 28-03-2018 CIG75_RS10710 3b5f36b9174908d61c6d81d387ea0fec 1506 SUPERFAMILY SSF52777 1264 1498 3.45E-55 T 28-03-2018 CIG75_RS10710 3b5f36b9174908d61c6d81d387ea0fec 1506 SUPERFAMILY SSF56801 438 1000 6.93E-167 T 28-03-2018 CIG75_RS10710 3b5f36b9174908d61c6d81d387ea0fec 1506 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1012 1027 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS10710 3b5f36b9174908d61c6d81d387ea0fec 1506 Pfam PF00550 Phosphopantetheine attachment site 990 1053 6.5E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10710 3b5f36b9174908d61c6d81d387ea0fec 1506 Gene3D G3DSA:2.30.38.10 787 868 5.6E-25 T 28-03-2018 CIG75_RS10710 3b5f36b9174908d61c6d81d387ea0fec 1506 Gene3D G3DSA:3.30.559.10 7 218 3.6E-45 T 28-03-2018 CIG75_RS10710 3b5f36b9174908d61c6d81d387ea0fec 1506 Gene3D G3DSA:3.30.559.10 1060 1282 6.4E-36 T 28-03-2018 CIG75_RS10710 3b5f36b9174908d61c6d81d387ea0fec 1506 Gene3D G3DSA:3.40.50.980 629 786 1.4E-31 T 28-03-2018 CIG75_RS10710 3b5f36b9174908d61c6d81d387ea0fec 1506 PIRSF PIRSF001617 596 928 9.5E-38 T 28-03-2018 CIG75_RS10710 3b5f36b9174908d61c6d81d387ea0fec 1506 PIRSF PIRSF001617 204 589 2.1E-22 T 28-03-2018 CIG75_RS10710 3b5f36b9174908d61c6d81d387ea0fec 1506 PIRSF PIRSF001617 1264 1504 0.39 T 28-03-2018 CIG75_RS10710 3b5f36b9174908d61c6d81d387ea0fec 1506 PIRSF PIRSF001617 923 1068 2.8E-25 T 28-03-2018 CIG75_RS10710 3b5f36b9174908d61c6d81d387ea0fec 1506 SUPERFAMILY SSF52777 202 466 8.56E-67 T 28-03-2018 CIG75_RS10710 3b5f36b9174908d61c6d81d387ea0fec 1506 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 502 902 7.0E-138 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS10710 3b5f36b9174908d61c6d81d387ea0fec 1506 Gene3D G3DSA:3.30.300.30 873 991 1.4E-42 T 28-03-2018 CIG75_RS10710 3b5f36b9174908d61c6d81d387ea0fec 1506 Pfam PF00668 Condensation domain 17 459 3.6E-118 T 28-03-2018 IPR001242 Condensation domain CIG75_RS10710 3b5f36b9174908d61c6d81d387ea0fec 1506 Pfam PF00668 Condensation domain 1076 1505 4.3E-88 T 28-03-2018 IPR001242 Condensation domain CIG75_RS10710 3b5f36b9174908d61c6d81d387ea0fec 1506 ProSitePatterns PS00455 Putative AMP-binding domain signature. 623 634 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS10710 3b5f36b9174908d61c6d81d387ea0fec 1506 Pfam PF13193 AMP-binding enzyme C-terminal domain 886 960 6.2E-15 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS10710 3b5f36b9174908d61c6d81d387ea0fec 1506 SUPERFAMILY SSF52777 20 196 4.0E-52 T 28-03-2018 CIG75_RS10710 3b5f36b9174908d61c6d81d387ea0fec 1506 SUPERFAMILY SSF52777 1079 1256 1.56E-42 T 28-03-2018 CIG75_RS10710 3b5f36b9174908d61c6d81d387ea0fec 1506 SMART SM00823 Phosphopantetheine attachment site 988 1057 5.7E-5 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS10710 3b5f36b9174908d61c6d81d387ea0fec 1506 Gene3D G3DSA:1.10.1200.10 992 1059 3.4E-23 T 28-03-2018 CIG75_RS10710 3b5f36b9174908d61c6d81d387ea0fec 1506 Pfam PF00501 AMP-binding enzyme 481 878 1.1E-103 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS14850 d0a9fcb6b31e054fdcd75369c8f91d27 603 Gene3D G3DSA:3.30.70.870 295 374 1.4E-28 T 28-03-2018 CIG75_RS14850 d0a9fcb6b31e054fdcd75369c8f91d27 603 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 10 180 1.1E-20 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CIG75_RS14850 d0a9fcb6b31e054fdcd75369c8f91d27 603 Hamap MF_00071 Elongation factor 4 [lepA]. 1 603 313.34 T 28-03-2018 IPR006297 Elongation factor 4 GO:0005525 CIG75_RS14850 d0a9fcb6b31e054fdcd75369c8f91d27 603 TIGRFAM TIGR01393 lepA: elongation factor 4 10 603 0.0 T 28-03-2018 IPR006297 Elongation factor 4 GO:0005525 CIG75_RS14850 d0a9fcb6b31e054fdcd75369c8f91d27 603 PRINTS PR00315 GTP-binding elongation factor signature 97 108 4.4E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CIG75_RS14850 d0a9fcb6b31e054fdcd75369c8f91d27 603 PRINTS PR00315 GTP-binding elongation factor signature 133 142 4.4E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CIG75_RS14850 d0a9fcb6b31e054fdcd75369c8f91d27 603 PRINTS PR00315 GTP-binding elongation factor signature 13 26 4.4E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CIG75_RS14850 d0a9fcb6b31e054fdcd75369c8f91d27 603 PRINTS PR00315 GTP-binding elongation factor signature 56 64 4.4E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CIG75_RS14850 d0a9fcb6b31e054fdcd75369c8f91d27 603 PRINTS PR00315 GTP-binding elongation factor signature 81 91 4.4E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CIG75_RS14850 d0a9fcb6b31e054fdcd75369c8f91d27 603 Gene3D G3DSA:2.40.30.10 196 294 6.5E-25 T 28-03-2018 CIG75_RS14850 d0a9fcb6b31e054fdcd75369c8f91d27 603 SUPERFAMILY SSF50447 173 295 5.74E-30 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CIG75_RS14850 d0a9fcb6b31e054fdcd75369c8f91d27 603 Pfam PF00679 Elongation factor G C-terminus 406 492 7.7E-25 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CIG75_RS14850 d0a9fcb6b31e054fdcd75369c8f91d27 603 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 49 64 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site CIG75_RS14850 d0a9fcb6b31e054fdcd75369c8f91d27 603 Gene3D G3DSA:3.40.50.300 1 195 2.5E-36 T 28-03-2018 CIG75_RS14850 d0a9fcb6b31e054fdcd75369c8f91d27 603 SUPERFAMILY SSF54980 299 377 5.76E-19 T 28-03-2018 IPR035647 EF-G domain III/V-like CIG75_RS14850 d0a9fcb6b31e054fdcd75369c8f91d27 603 Gene3D G3DSA:3.30.70.240 398 557 9.1E-32 T 28-03-2018 CIG75_RS14850 d0a9fcb6b31e054fdcd75369c8f91d27 603 SUPERFAMILY SSF54980 406 501 1.25E-26 T 28-03-2018 IPR035647 EF-G domain III/V-like CIG75_RS14850 d0a9fcb6b31e054fdcd75369c8f91d27 603 Pfam PF00009 Elongation factor Tu GTP binding domain 10 188 6.4E-54 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CIG75_RS14850 d0a9fcb6b31e054fdcd75369c8f91d27 603 SMART SM00838 405 493 8.1E-4 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CIG75_RS14850 d0a9fcb6b31e054fdcd75369c8f91d27 603 SUPERFAMILY SSF52540 7 212 3.99E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS14850 d0a9fcb6b31e054fdcd75369c8f91d27 603 Pfam PF06421 GTP-binding protein LepA C-terminus 495 601 1.0E-53 T 28-03-2018 IPR013842 GTP-binding protein LepA, C-terminal CIG75_RS14850 d0a9fcb6b31e054fdcd75369c8f91d27 603 Pfam PF03144 Elongation factor Tu domain 2 212 282 5.7E-10 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CIG75_RS04650 9383cb82b4091c7fbd491ddbc5626bd9 353 Gene3D G3DSA:3.40.47.10 211 353 2.7E-34 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS04650 9383cb82b4091c7fbd491ddbc5626bd9 353 PIRSF PIRSF000451 1 353 1.7E-122 T 28-03-2018 IPR011141 Polyketide synthase, type III GO:0009058|GO:0016747 CIG75_RS04650 9383cb82b4091c7fbd491ddbc5626bd9 353 Gene3D G3DSA:3.40.47.10 3 204 9.9E-29 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS04650 9383cb82b4091c7fbd491ddbc5626bd9 353 ProSitePatterns PS00441 Chalcone and stilbene synthases active site. 131 147 - T 28-03-2018 IPR018088 Chalcone/stilbene synthase, active site GO:0009058|GO:0016746 KEGG: 00941+2.3.1.74|MetaCyc: PWY-5135|MetaCyc: PWY-6316|MetaCyc: PWY-6787|MetaCyc: PWY-7397 CIG75_RS04650 9383cb82b4091c7fbd491ddbc5626bd9 353 SUPERFAMILY SSF53901 6 353 1.29E-52 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS04650 9383cb82b4091c7fbd491ddbc5626bd9 353 Pfam PF02797 Chalcone and stilbene synthases, C-terminal domain 214 352 3.9E-21 T 28-03-2018 IPR012328 Chalcone/stilbene synthase, C-terminal CIG75_RS04650 9383cb82b4091c7fbd491ddbc5626bd9 353 Pfam PF00195 Chalcone and stilbene synthases, N-terminal domain 4 201 2.1E-25 T 28-03-2018 IPR001099 Chalcone/stilbene synthase, N-terminal CIG75_RS04605 6eae9920321e57144b5079a1bbccc958 513 Gene3D G3DSA:3.40.50.880 31 345 5.3E-36 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CIG75_RS04605 6eae9920321e57144b5079a1bbccc958 513 SUPERFAMILY SSF52317 40 156 1.63E-8 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CIG75_RS04605 6eae9920321e57144b5079a1bbccc958 513 SUPERFAMILY SSF52317 193 324 1.63E-8 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CIG75_RS20465 ae7e21d221f9a88328d14a508be25b1a 259 SUPERFAMILY SSF53335 21 209 3.7E-31 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CIG75_RS20465 ae7e21d221f9a88328d14a508be25b1a 259 Gene3D G3DSA:3.40.50.150 15 256 8.9E-38 T 28-03-2018 CIG75_RS20465 ae7e21d221f9a88328d14a508be25b1a 259 Pfam PF05175 Methyltransferase small domain 29 139 1.0E-14 T 28-03-2018 IPR007848 Methyltransferase small domain GO:0008168 CIG75_RS20465 ae7e21d221f9a88328d14a508be25b1a 259 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 128 134 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CIG75_RS03080 18659817f5ef766cc86ecfbb6d9800c9 770 Gene3D G3DSA:3.40.50.300 609 770 1.9E-31 T 28-03-2018 CIG75_RS03080 18659817f5ef766cc86ecfbb6d9800c9 770 Gene3D G3DSA:3.40.50.300 210 592 5.8E-35 T 28-03-2018 CIG75_RS03080 18659817f5ef766cc86ecfbb6d9800c9 770 SUPERFAMILY SSF52540 204 363 2.43E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS03080 18659817f5ef766cc86ecfbb6d9800c9 770 SUPERFAMILY SSF52540 497 764 2.43E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS03080 18659817f5ef766cc86ecfbb6d9800c9 770 Pfam PF13538 UvrD-like helicase C-terminal domain 713 758 1.9E-9 T 28-03-2018 IPR027785 UvrD-like helicase C-terminal domain CIG75_RS03080 18659817f5ef766cc86ecfbb6d9800c9 770 Pfam PF13245 AAA domain 216 584 1.5E-11 T 28-03-2018 CIG75_RS01345 bdae13e3cb7b764b753bb4ced7bd603c 292 Pfam PF00795 Carbon-nitrogen hydrolase 18 225 2.5E-27 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CIG75_RS01345 bdae13e3cb7b764b753bb4ced7bd603c 292 SUPERFAMILY SSF56317 6 272 7.59E-50 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CIG75_RS01345 bdae13e3cb7b764b753bb4ced7bd603c 292 Gene3D G3DSA:3.60.110.10 2 290 7.0E-47 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CIG75_RS01345 bdae13e3cb7b764b753bb4ced7bd603c 292 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 150 170 - T 28-03-2018 IPR001110 Uncharacterised protein family UPF0012, conserved site CIG75_RS18525 c969529cf3b0f5d49f6f9a2492ee5927 742 SUPERFAMILY SSF102114 297 515 3.14E-27 T 28-03-2018 CIG75_RS18525 c969529cf3b0f5d49f6f9a2492ee5927 742 SMART SM00729 318 532 1.4E-26 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CIG75_RS18525 c969529cf3b0f5d49f6f9a2492ee5927 742 Pfam PF04055 Radical SAM superfamily 323 486 6.0E-12 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CIG75_RS18525 c969529cf3b0f5d49f6f9a2492ee5927 742 Gene3D G3DSA:3.20.20.70 274 560 5.8E-26 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CIG75_RS18525 c969529cf3b0f5d49f6f9a2492ee5927 742 Gene3D G3DSA:3.40.50.280 19 263 2.4E-4 T 28-03-2018 CIG75_RS16420 e6bde29441dc7112898911155168f0b9 309 PIRSF PIRSF000401 8 308 4.4E-43 T 28-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 CIG75_RS16420 e6bde29441dc7112898911155168f0b9 309 SUPERFAMILY SSF53335 125 303 3.14E-32 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CIG75_RS16420 e6bde29441dc7112898911155168f0b9 309 Gene3D G3DSA:3.40.50.150 111 306 5.8E-32 T 28-03-2018 CIG75_RS16420 e6bde29441dc7112898911155168f0b9 309 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 10 305 1.3E-42 T 28-03-2018 CIG75_RS11385 c52e53f130c46f9e19bfedf2a908aa5e 202 Pfam PF09335 SNARE associated Golgi protein 31 157 4.1E-21 T 28-03-2018 IPR032816 SNARE associated Golgi protein CIG75_RS15625 ab57b129f8b8c118d1c742b2e25394c9 208 Gene3D G3DSA:1.20.58.300 12 91 0.0097 T 28-03-2018 CIG75_RS15625 ab57b129f8b8c118d1c742b2e25394c9 208 SUPERFAMILY SSF101262 5 207 4.32E-54 T 28-03-2018 IPR007044 Cyclodeaminase/cyclohydrolase GO:0003824|GO:0044237 KEGG: 00340+2.1.2.5|KEGG: 00670+4.3.1.4+2.1.2.5|MetaCyc: PWY-5030|MetaCyc: PWY-5497|Reactome: R-HSA-70921 CIG75_RS15625 ab57b129f8b8c118d1c742b2e25394c9 208 Pfam PF04961 Formiminotransferase-cyclodeaminase 8 185 5.4E-58 T 28-03-2018 IPR007044 Cyclodeaminase/cyclohydrolase GO:0003824|GO:0044237 KEGG: 00340+2.1.2.5|KEGG: 00670+4.3.1.4+2.1.2.5|MetaCyc: PWY-5030|MetaCyc: PWY-5497|Reactome: R-HSA-70921 CIG75_RS13755 f1a164eb52d848ca291ddd02a040929c 284 Gene3D G3DSA:3.90.1200.10 88 258 1.3E-15 T 28-03-2018 CIG75_RS13755 f1a164eb52d848ca291ddd02a040929c 284 Gene3D G3DSA:3.30.200.20 1 87 1.5E-4 T 28-03-2018 CIG75_RS13755 f1a164eb52d848ca291ddd02a040929c 284 SUPERFAMILY SSF56112 2 244 1.19E-35 T 28-03-2018 IPR011009 Protein kinase-like domain CIG75_RS13755 f1a164eb52d848ca291ddd02a040929c 284 Pfam PF01636 Phosphotransferase enzyme family 17 234 3.6E-29 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CIG75_RS02805 35464c5618ebc78f9a99d81edd051b2a 2279 Pfam PF13193 AMP-binding enzyme C-terminal domain 1649 1724 2.2E-7 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS02805 35464c5618ebc78f9a99d81edd051b2a 2279 Gene3D G3DSA:1.10.1200.10 673 764 1.5E-13 T 28-03-2018 CIG75_RS02805 35464c5618ebc78f9a99d81edd051b2a 2279 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 203 219 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CIG75_RS02805 35464c5618ebc78f9a99d81edd051b2a 2279 SUPERFAMILY SSF52777 1823 1987 1.78E-19 T 28-03-2018 CIG75_RS02805 35464c5618ebc78f9a99d81edd051b2a 2279 Pfam PF00501 AMP-binding enzyme 1245 1641 1.3E-91 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS02805 35464c5618ebc78f9a99d81edd051b2a 2279 SUPERFAMILY SSF52777 786 982 2.0E-35 T 28-03-2018 CIG75_RS02805 35464c5618ebc78f9a99d81edd051b2a 2279 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1266 1664 5.1E-128 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS02805 35464c5618ebc78f9a99d81edd051b2a 2279 Gene3D G3DSA:3.40.50.980 1236 1390 2.9E-39 T 28-03-2018 CIG75_RS02805 35464c5618ebc78f9a99d81edd051b2a 2279 SUPERFAMILY SSF47336 688 759 4.45E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS02805 35464c5618ebc78f9a99d81edd051b2a 2279 SMART SM00823 Phosphopantetheine attachment site 694 763 0.096 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS02805 35464c5618ebc78f9a99d81edd051b2a 2279 SMART SM00823 Phosphopantetheine attachment site 1749 1816 3.2E-5 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS02805 35464c5618ebc78f9a99d81edd051b2a 2279 Gene3D G3DSA:2.30.38.10 1551 1630 2.1E-22 T 28-03-2018 CIG75_RS02805 35464c5618ebc78f9a99d81edd051b2a 2279 Gene3D G3DSA:3.30.300.30 1636 1751 8.8E-31 T 28-03-2018 CIG75_RS02805 35464c5618ebc78f9a99d81edd051b2a 2279 Pfam PF00668 Condensation domain 1840 2259 6.4E-42 T 28-03-2018 IPR001242 Condensation domain CIG75_RS02805 35464c5618ebc78f9a99d81edd051b2a 2279 Pfam PF00668 Condensation domain 791 1224 4.6E-99 T 28-03-2018 IPR001242 Condensation domain CIG75_RS02805 35464c5618ebc78f9a99d81edd051b2a 2279 Gene3D G3DSA:3.40.50.980 1391 1540 1.2E-34 T 28-03-2018 CIG75_RS02805 35464c5618ebc78f9a99d81edd051b2a 2279 SUPERFAMILY SSF47336 1742 1812 3.4E-16 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS02805 35464c5618ebc78f9a99d81edd051b2a 2279 SUPERFAMILY SSF52777 2001 2247 1.67E-26 T 28-03-2018 CIG75_RS02805 35464c5618ebc78f9a99d81edd051b2a 2279 Gene3D G3DSA:3.30.559.10 1816 2006 9.1E-20 T 28-03-2018 CIG75_RS02805 35464c5618ebc78f9a99d81edd051b2a 2279 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1387 1398 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS02805 35464c5618ebc78f9a99d81edd051b2a 2279 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 415 520 1.6E-13 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS02805 35464c5618ebc78f9a99d81edd051b2a 2279 Gene3D G3DSA:3.40.47.10 38 299 6.8E-63 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS02805 35464c5618ebc78f9a99d81edd051b2a 2279 SUPERFAMILY SSF56801 1203 1762 2.09E-147 T 28-03-2018 CIG75_RS02805 35464c5618ebc78f9a99d81edd051b2a 2279 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 295 412 2.7E-43 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CIG75_RS02805 35464c5618ebc78f9a99d81edd051b2a 2279 SUPERFAMILY SSF52777 972 1232 2.0E-61 T 28-03-2018 CIG75_RS02805 35464c5618ebc78f9a99d81edd051b2a 2279 SUPERFAMILY SSF53901 45 403 2.81E-80 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS02805 35464c5618ebc78f9a99d81edd051b2a 2279 Gene3D G3DSA:3.30.559.10 769 976 2.6E-36 T 28-03-2018 CIG75_RS02805 35464c5618ebc78f9a99d81edd051b2a 2279 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 48 287 3.6E-62 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CIG75_RS02805 35464c5618ebc78f9a99d81edd051b2a 2279 Gene3D G3DSA:3.40.47.10 302 463 3.5E-55 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS02805 35464c5618ebc78f9a99d81edd051b2a 2279 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 2117 2271 1.1E-24 T 28-03-2018 IPR010060 Non-ribosomal peptide synthase CIG75_RS02805 35464c5618ebc78f9a99d81edd051b2a 2279 Gene3D G3DSA:1.10.1200.10 1752 1815 9.9E-21 T 28-03-2018 CIG75_RS02805 35464c5618ebc78f9a99d81edd051b2a 2279 SMART SM00825 Beta-ketoacyl synthase 48 465 1.1E-153 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CIG75_RS02805 35464c5618ebc78f9a99d81edd051b2a 2279 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1772 1787 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS02805 35464c5618ebc78f9a99d81edd051b2a 2279 ProSitePatterns PS00012 Phosphopantetheine attachment site. 718 733 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS02805 35464c5618ebc78f9a99d81edd051b2a 2279 Pfam PF00550 Phosphopantetheine attachment site 1752 1811 5.1E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS02805 35464c5618ebc78f9a99d81edd051b2a 2279 Pfam PF00550 Phosphopantetheine attachment site 700 758 4.6E-8 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS13670 38d1f15f4c0b1c7bb230ae3e8b3cbaf5 433 SUPERFAMILY SSF54373 180 282 1.61E-19 T 28-03-2018 CIG75_RS13670 38d1f15f4c0b1c7bb230ae3e8b3cbaf5 433 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 151 166 4.7E-7 T 28-03-2018 CIG75_RS13670 38d1f15f4c0b1c7bb230ae3e8b3cbaf5 433 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 4.7E-7 T 28-03-2018 CIG75_RS13670 38d1f15f4c0b1c7bb230ae3e8b3cbaf5 433 Gene3D G3DSA:3.50.50.60 1 361 2.7E-44 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS13670 38d1f15f4c0b1c7bb230ae3e8b3cbaf5 433 Pfam PF12831 FAD dependent oxidoreductase 5 148 2.4E-9 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS13670 38d1f15f4c0b1c7bb230ae3e8b3cbaf5 433 SUPERFAMILY SSF51905 290 351 8.09E-42 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS13670 38d1f15f4c0b1c7bb230ae3e8b3cbaf5 433 SUPERFAMILY SSF51905 1 178 8.09E-42 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS06410 8f59ffc14c9463a16bb1d0528f9fe0e1 761 SMART SM00954 255 365 6.0E-67 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 CIG75_RS06410 8f59ffc14c9463a16bb1d0528f9fe0e1 761 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 46 758 1.3E-248 T 28-03-2018 IPR004811 RelA/SpoT family GO:0015969 CIG75_RS06410 8f59ffc14c9463a16bb1d0528f9fe0e1 761 Pfam PF02824 TGS domain 428 487 1.6E-22 T 28-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 CIG75_RS06410 8f59ffc14c9463a16bb1d0528f9fe0e1 761 Pfam PF13291 ACT domain 683 758 5.0E-20 T 28-03-2018 IPR002912 ACT domain CIG75_RS06410 8f59ffc14c9463a16bb1d0528f9fe0e1 761 SUPERFAMILY SSF81271 415 487 4.58E-24 T 28-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CIG75_RS06410 8f59ffc14c9463a16bb1d0528f9fe0e1 761 Gene3D G3DSA:3.30.460.10 208 346 1.7E-45 T 28-03-2018 CIG75_RS06410 8f59ffc14c9463a16bb1d0528f9fe0e1 761 Gene3D G3DSA:3.30.70.260 681 761 3.8E-9 T 28-03-2018 CIG75_RS06410 8f59ffc14c9463a16bb1d0528f9fe0e1 761 Gene3D G3DSA:3.10.20.30 422 495 1.0E-25 T 28-03-2018 IPR012675 Beta-grasp domain CIG75_RS06410 8f59ffc14c9463a16bb1d0528f9fe0e1 761 Pfam PF04607 Region found in RelA / SpoT proteins 255 365 8.5E-39 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 CIG75_RS06410 8f59ffc14c9463a16bb1d0528f9fe0e1 761 SUPERFAMILY SSF81301 200 432 2.62E-64 T 28-03-2018 CIG75_RS06410 8f59ffc14c9463a16bb1d0528f9fe0e1 761 SUPERFAMILY SSF109604 26 210 3.77E-75 T 28-03-2018 CIG75_RS06410 8f59ffc14c9463a16bb1d0528f9fe0e1 761 SMART SM00471 61 173 1.0E-10 T 28-03-2018 IPR003607 HD/PDEase domain CIG75_RS06410 8f59ffc14c9463a16bb1d0528f9fe0e1 761 Pfam PF13328 HD domain 46 195 1.7E-54 T 28-03-2018 IPR003607 HD/PDEase domain CIG75_RS06410 8f59ffc14c9463a16bb1d0528f9fe0e1 761 SUPERFAMILY SSF55021 682 761 2.15E-9 T 28-03-2018 CIG75_RS06710 ac2da994fd6c9bca6ccc0106d9c7f4b7 2826 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2370 2381 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS06710 ac2da994fd6c9bca6ccc0106d9c7f4b7 2826 SUPERFAMILY SSF56801 9 564 6.02E-110 T 28-03-2018 CIG75_RS06710 ac2da994fd6c9bca6ccc0106d9c7f4b7 2826 SUPERFAMILY SSF56801 1124 1694 1.44E-172 T 28-03-2018 CIG75_RS06710 ac2da994fd6c9bca6ccc0106d9c7f4b7 2826 Gene3D G3DSA:2.30.38.10 371 453 3.5E-20 T 28-03-2018 CIG75_RS06710 ac2da994fd6c9bca6ccc0106d9c7f4b7 2826 Gene3D G3DSA:3.40.50.980 175 340 2.9E-33 T 28-03-2018 CIG75_RS06710 ac2da994fd6c9bca6ccc0106d9c7f4b7 2826 Gene3D G3DSA:3.40.50.980 1312 1471 2.8E-41 T 28-03-2018 CIG75_RS06710 ac2da994fd6c9bca6ccc0106d9c7f4b7 2826 Gene3D G3DSA:3.40.50.980 2376 2535 5.2E-28 T 28-03-2018 CIG75_RS06710 ac2da994fd6c9bca6ccc0106d9c7f4b7 2826 SUPERFAMILY SSF52777 1951 2215 3.67E-65 T 28-03-2018 CIG75_RS06710 ac2da994fd6c9bca6ccc0106d9c7f4b7 2826 ProSitePatterns PS00455 Putative AMP-binding domain signature. 168 179 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS06710 ac2da994fd6c9bca6ccc0106d9c7f4b7 2826 SUPERFAMILY SSF47336 1673 1778 2.22E-20 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS06710 ac2da994fd6c9bca6ccc0106d9c7f4b7 2826 Gene3D G3DSA:1.10.1200.10 1687 1749 1.0E-22 T 28-03-2018 CIG75_RS06710 ac2da994fd6c9bca6ccc0106d9c7f4b7 2826 SUPERFAMILY SSF52777 875 1153 1.45E-57 T 28-03-2018 CIG75_RS06710 ac2da994fd6c9bca6ccc0106d9c7f4b7 2826 Gene3D G3DSA:3.40.50.980 2219 2375 3.8E-50 T 28-03-2018 CIG75_RS06710 ac2da994fd6c9bca6ccc0106d9c7f4b7 2826 Gene3D G3DSA:3.40.50.980 7 174 1.9E-34 T 28-03-2018 CIG75_RS06710 ac2da994fd6c9bca6ccc0106d9c7f4b7 2826 Gene3D G3DSA:3.40.50.980 1158 1311 5.9E-53 T 28-03-2018 CIG75_RS06710 ac2da994fd6c9bca6ccc0106d9c7f4b7 2826 Gene3D G3DSA:2.30.38.10 2538 2618 3.9E-24 T 28-03-2018 CIG75_RS06710 ac2da994fd6c9bca6ccc0106d9c7f4b7 2826 Gene3D G3DSA:2.30.38.10 1487 1564 8.1E-25 T 28-03-2018 CIG75_RS06710 ac2da994fd6c9bca6ccc0106d9c7f4b7 2826 SMART SM01294 610 676 0.0028 T 28-03-2018 CIG75_RS06710 ac2da994fd6c9bca6ccc0106d9c7f4b7 2826 Pfam PF00668 Condensation domain 1763 2207 5.3E-117 T 28-03-2018 IPR001242 Condensation domain CIG75_RS06710 ac2da994fd6c9bca6ccc0106d9c7f4b7 2826 Pfam PF00668 Condensation domain 697 1146 7.1E-110 T 28-03-2018 IPR001242 Condensation domain CIG75_RS06710 ac2da994fd6c9bca6ccc0106d9c7f4b7 2826 SUPERFAMILY SSF47336 2727 2800 1.7E-20 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS06710 ac2da994fd6c9bca6ccc0106d9c7f4b7 2826 Pfam PF00550 Phosphopantetheine attachment site 1683 1746 1.4E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS06710 ac2da994fd6c9bca6ccc0106d9c7f4b7 2826 Pfam PF00550 Phosphopantetheine attachment site 2740 2800 1.1E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS06710 ac2da994fd6c9bca6ccc0106d9c7f4b7 2826 Pfam PF00550 Phosphopantetheine attachment site 611 672 7.7E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS06710 ac2da994fd6c9bca6ccc0106d9c7f4b7 2826 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2759 2774 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS06710 ac2da994fd6c9bca6ccc0106d9c7f4b7 2826 SUPERFAMILY SSF47336 604 686 4.71E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS06710 ac2da994fd6c9bca6ccc0106d9c7f4b7 2826 Pfam PF00501 AMP-binding enzyme 1166 1574 2.6E-110 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS06710 ac2da994fd6c9bca6ccc0106d9c7f4b7 2826 Pfam PF00501 AMP-binding enzyme 17 461 1.6E-85 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS06710 ac2da994fd6c9bca6ccc0106d9c7f4b7 2826 Pfam PF00501 AMP-binding enzyme 2228 2628 4.1E-97 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS06710 ac2da994fd6c9bca6ccc0106d9c7f4b7 2826 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2249 2652 2.6E-132 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS06710 ac2da994fd6c9bca6ccc0106d9c7f4b7 2826 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1187 1598 6.6E-139 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS06710 ac2da994fd6c9bca6ccc0106d9c7f4b7 2826 Gene3D G3DSA:3.30.300.30 454 562 4.6E-16 T 28-03-2018 CIG75_RS06710 ac2da994fd6c9bca6ccc0106d9c7f4b7 2826 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1705 1720 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS06710 ac2da994fd6c9bca6ccc0106d9c7f4b7 2826 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1306 1317 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS06710 ac2da994fd6c9bca6ccc0106d9c7f4b7 2826 Gene3D G3DSA:3.30.300.30 2623 2740 1.3E-43 T 28-03-2018 CIG75_RS06710 ac2da994fd6c9bca6ccc0106d9c7f4b7 2826 Gene3D G3DSA:3.30.300.30 1569 1686 8.8E-41 T 28-03-2018 CIG75_RS06710 ac2da994fd6c9bca6ccc0106d9c7f4b7 2826 SUPERFAMILY SSF56801 2186 2748 1.7E-160 T 28-03-2018 CIG75_RS06710 ac2da994fd6c9bca6ccc0106d9c7f4b7 2826 SUPERFAMILY SSF52777 1768 1945 1.63E-50 T 28-03-2018 CIG75_RS06710 ac2da994fd6c9bca6ccc0106d9c7f4b7 2826 SUPERFAMILY SSF52777 700 867 1.78E-47 T 28-03-2018 CIG75_RS06710 ac2da994fd6c9bca6ccc0106d9c7f4b7 2826 Gene3D G3DSA:1.10.1200.10 590 686 6.4E-15 T 28-03-2018 CIG75_RS06710 ac2da994fd6c9bca6ccc0106d9c7f4b7 2826 Pfam PF13193 AMP-binding enzyme C-terminal domain 1582 1655 4.7E-12 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS06710 ac2da994fd6c9bca6ccc0106d9c7f4b7 2826 Pfam PF13193 AMP-binding enzyme C-terminal domain 2636 2710 1.6E-12 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS06710 ac2da994fd6c9bca6ccc0106d9c7f4b7 2826 SMART SM00823 Phosphopantetheine attachment site 2735 2804 3.2E-4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS06710 ac2da994fd6c9bca6ccc0106d9c7f4b7 2826 SMART SM00823 Phosphopantetheine attachment site 1681 1750 4.5E-4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS06710 ac2da994fd6c9bca6ccc0106d9c7f4b7 2826 SMART SM00823 Phosphopantetheine attachment site 609 680 4.1E-14 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS06710 ac2da994fd6c9bca6ccc0106d9c7f4b7 2826 Gene3D G3DSA:1.10.1200.10 2741 2824 8.5E-24 T 28-03-2018 CIG75_RS06710 ac2da994fd6c9bca6ccc0106d9c7f4b7 2826 Gene3D G3DSA:3.30.559.10 1750 1965 7.3E-47 T 28-03-2018 CIG75_RS06710 ac2da994fd6c9bca6ccc0106d9c7f4b7 2826 Gene3D G3DSA:3.30.559.10 687 889 1.8E-41 T 28-03-2018 CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 SUPERFAMILY SSF52777 50 230 6.45E-45 T 28-03-2018 CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 Gene3D G3DSA:1.10.1200.10 2557 2619 7.3E-20 T 28-03-2018 CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 Gene3D G3DSA:1.10.1200.10 5147 5212 4.7E-21 T 28-03-2018 CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 Gene3D G3DSA:1.10.1200.10 1028 1092 2.5E-21 T 28-03-2018 CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 Gene3D G3DSA:1.10.1200.10 3605 3667 6.5E-18 T 28-03-2018 CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 ProSitePatterns PS00455 Putative AMP-binding domain signature. 3242 3253 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3625 3640 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 SUPERFAMILY SSF56801 474 1035 1.96E-159 T 28-03-2018 CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 Pfam PF00501 AMP-binding enzyme 516 913 1.5E-105 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 Pfam PF00501 AMP-binding enzyme 3104 3492 1.3E-94 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 Pfam PF00501 AMP-binding enzyme 4623 5030 4.8E-94 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 Pfam PF00501 AMP-binding enzyme 2042 2440 8.0E-102 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 SUPERFAMILY SSF52777 3685 3860 1.45E-34 T 28-03-2018 CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 SUPERFAMILY SSF47336 5133 5206 1.7E-18 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 Pfam PF00668 Condensation domain 4156 4603 9.5E-105 T 28-03-2018 IPR001242 Condensation domain CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 Pfam PF00668 Condensation domain 2638 3085 2.6E-118 T 28-03-2018 IPR001242 Condensation domain CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 Pfam PF00668 Condensation domain 1105 1546 1.9E-82 T 28-03-2018 IPR001242 Condensation domain CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 Pfam PF00668 Condensation domain 1575 2022 3.4E-100 T 28-03-2018 IPR001242 Condensation domain CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 Pfam PF00668 Condensation domain 3681 4131 4.5E-83 T 28-03-2018 IPR001242 Condensation domain CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 Pfam PF00668 Condensation domain 48 494 6.6E-117 T 28-03-2018 IPR001242 Condensation domain CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 Pfam PF00975 Thioesterase domain 5230 5475 8.8E-30 T 28-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 SUPERFAMILY SSF52777 1293 1536 6.12E-44 T 28-03-2018 CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 ProSitePatterns PS00455 Putative AMP-binding domain signature. 4765 4776 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 Gene3D G3DSA:3.30.559.10 3668 3871 5.2E-26 T 28-03-2018 CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 SUPERFAMILY SSF52777 238 477 9.0E-66 T 28-03-2018 CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 Gene3D G3DSA:3.40.50.980 506 662 1.8E-49 T 28-03-2018 CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 Gene3D G3DSA:3.40.50.980 4614 4770 1.2E-48 T 28-03-2018 CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 Gene3D G3DSA:3.40.50.980 3096 3247 6.0E-47 T 28-03-2018 CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 Gene3D G3DSA:3.40.50.980 2036 2189 1.8E-45 T 28-03-2018 CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 SMART SM00824 Thioesterase 5235 5486 2.3E-4 T 28-03-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 SUPERFAMILY SSF47336 2546 2652 4.45E-17 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 Gene3D G3DSA:2.30.38.10 2353 2430 3.1E-22 T 28-03-2018 CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 Gene3D G3DSA:2.30.38.10 4938 5020 1.2E-21 T 28-03-2018 CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 Gene3D G3DSA:2.30.38.10 826 903 1.9E-21 T 28-03-2018 CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 Gene3D G3DSA:3.30.559.10 15 254 1.2E-41 T 28-03-2018 CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 Gene3D G3DSA:3.30.559.10 2620 2845 8.2E-50 T 28-03-2018 CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 Gene3D G3DSA:3.30.559.10 1562 1777 3.0E-41 T 28-03-2018 CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 Gene3D G3DSA:3.30.559.10 4150 4355 3.9E-43 T 28-03-2018 CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 SUPERFAMILY SSF52777 3869 4120 6.67E-44 T 28-03-2018 CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 Pfam PF00550 Phosphopantetheine attachment site 1026 1086 6.4E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 Pfam PF00550 Phosphopantetheine attachment site 5143 5206 1.1E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 Pfam PF00550 Phosphopantetheine attachment site 2556 2615 3.3E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 Pfam PF00550 Phosphopantetheine attachment site 3603 3664 1.1E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1048 1063 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 Pfam PF13193 AMP-binding enzyme C-terminal domain 2448 2523 2.1E-10 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 Pfam PF13193 AMP-binding enzyme C-terminal domain 921 996 2.6E-11 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 Pfam PF13193 AMP-binding enzyme C-terminal domain 5038 5113 3.1E-11 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 Pfam PF13193 AMP-binding enzyme C-terminal domain 3500 3574 1.2E-11 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2575 2590 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 SUPERFAMILY SSF52777 1580 1757 1.22E-42 T 28-03-2018 CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 SUPERFAMILY SSF52777 2642 2819 7.11E-49 T 28-03-2018 CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 SUPERFAMILY SSF52777 1758 2011 2.67E-51 T 28-03-2018 CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 Gene3D G3DSA:3.30.559.10 1093 1298 5.6E-32 T 28-03-2018 CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 SMART SM00823 Phosphopantetheine attachment site 1024 1092 0.0039 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 SMART SM00823 Phosphopantetheine attachment site 2551 2620 6.8E-4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 SMART SM00823 Phosphopantetheine attachment site 3601 3669 0.044 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 SMART SM00823 Phosphopantetheine attachment site 5141 5210 0.0017 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 Gene3D G3DSA:2.30.38.10 3401 3485 8.0E-22 T 28-03-2018 CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 SUPERFAMILY SSF52777 2826 3072 1.89E-67 T 28-03-2018 CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 SUPERFAMILY SSF52777 4340 4607 2.82E-55 T 28-03-2018 CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 536 937 2.2E-122 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2063 2464 3.0E-121 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 3125 3515 1.3E-129 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 4644 5054 3.7E-128 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 SUPERFAMILY SSF53474 5208 5490 2.34E-57 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 1412 1559 4.7E-34 T 28-03-2018 IPR010060 Non-ribosomal peptide synthase CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 3989 4143 6.1E-47 T 28-03-2018 IPR010060 Non-ribosomal peptide synthase CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 SUPERFAMILY SSF56801 2000 2563 1.31E-151 T 28-03-2018 CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 SUPERFAMILY SSF52777 1102 1303 2.78E-38 T 28-03-2018 CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 Gene3D G3DSA:3.30.300.30 3487 3604 1.6E-42 T 28-03-2018 CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 Gene3D G3DSA:3.30.300.30 2435 2556 3.5E-38 T 28-03-2018 CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 Gene3D G3DSA:3.30.300.30 5025 5146 5.5E-40 T 28-03-2018 CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 Gene3D G3DSA:3.30.300.30 908 1027 1.1E-42 T 28-03-2018 CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 SUPERFAMILY SSF52777 4161 4338 6.67E-47 T 28-03-2018 CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 Gene3D G3DSA:3.40.50.1820 5221 5491 2.0E-22 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 SUPERFAMILY SSF47336 1016 1086 1.7E-18 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 ProSitePatterns PS00455 Putative AMP-binding domain signature. 657 668 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2184 2195 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 SUPERFAMILY SSF56801 4598 5154 1.83E-163 T 28-03-2018 CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 Gene3D G3DSA:3.40.50.980 3248 3400 6.4E-28 T 28-03-2018 CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 Gene3D G3DSA:3.40.50.980 2190 2352 1.0E-31 T 28-03-2018 CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 Gene3D G3DSA:3.40.50.980 4771 4935 3.9E-34 T 28-03-2018 CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 Gene3D G3DSA:3.40.50.980 663 825 1.3E-34 T 28-03-2018 CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 SUPERFAMILY SSF56801 3069 3614 7.33E-151 T 28-03-2018 CIG75_RS10315 82ca0a969e73927831271ee23b10da5a 5499 SUPERFAMILY SSF47336 3593 3665 3.93E-17 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS11780 478f39bc9288c0dc5c36b1d150a88dce 318 Pfam PF01687 Riboflavin kinase 187 308 9.0E-38 T 28-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 CIG75_RS11780 478f39bc9288c0dc5c36b1d150a88dce 318 Gene3D G3DSA:3.40.50.620 10 182 2.2E-42 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CIG75_RS11780 478f39bc9288c0dc5c36b1d150a88dce 318 SUPERFAMILY SSF52374 20 179 3.13E-32 T 28-03-2018 CIG75_RS11780 478f39bc9288c0dc5c36b1d150a88dce 318 PIRSF PIRSF004491 4 314 4.8E-102 T 28-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 CIG75_RS11780 478f39bc9288c0dc5c36b1d150a88dce 318 SMART SM00904 186 311 4.5E-59 T 28-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 CIG75_RS11780 478f39bc9288c0dc5c36b1d150a88dce 318 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 22 64 8.5E-9 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CIG75_RS11780 478f39bc9288c0dc5c36b1d150a88dce 318 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 22 308 2.8E-81 T 28-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 CIG75_RS11780 478f39bc9288c0dc5c36b1d150a88dce 318 SUPERFAMILY SSF82114 178 312 1.24E-45 T 28-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 CIG75_RS11780 478f39bc9288c0dc5c36b1d150a88dce 318 Pfam PF06574 FAD synthetase 19 169 2.7E-47 T 28-03-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 CIG75_RS11780 478f39bc9288c0dc5c36b1d150a88dce 318 Gene3D G3DSA:2.40.30.30 183 313 3.3E-41 T 28-03-2018 IPR023465 Riboflavin kinase domain GO:0008531|GO:0009231 Reactome: R-HSA-196843 CIG75_RS02790 76f2509685551eac2827ae370ef10a74 423 SUPERFAMILY SSF55048 130 197 1.44E-10 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CIG75_RS02790 76f2509685551eac2827ae370ef10a74 423 Gene3D G3DSA:3.40.366.10 3 139 3.5E-33 T 28-03-2018 CIG75_RS02790 76f2509685551eac2827ae370ef10a74 423 SUPERFAMILY SSF52151 198 298 1.67E-62 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CIG75_RS02790 76f2509685551eac2827ae370ef10a74 423 SUPERFAMILY SSF52151 3 128 1.67E-62 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CIG75_RS02790 76f2509685551eac2827ae370ef10a74 423 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 3 289 2.5E-83 T 28-03-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 CIG75_RS02790 76f2509685551eac2827ae370ef10a74 423 Gene3D G3DSA:3.30.70.250 140 185 2.7E-14 T 28-03-2018 CIG75_RS02790 76f2509685551eac2827ae370ef10a74 423 Pfam PF00698 Acyl transferase domain 7 292 6.6E-26 T 28-03-2018 IPR014043 Acyl transferase CIG75_RS02790 76f2509685551eac2827ae370ef10a74 423 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 7 306 8.5E-24 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CIG75_RS02790 76f2509685551eac2827ae370ef10a74 423 Gene3D G3DSA:3.40.366.10 186 312 6.6E-26 T 28-03-2018 CIG75_RS00045 a131eed6ce934807570d24f47b3fff11 476 SMART SM01274 93 226 1.5E-80 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CIG75_RS00045 a131eed6ce934807570d24f47b3fff11 476 SUPERFAMILY SSF51735 238 472 1.97E-76 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS00045 a131eed6ce934807570d24f47b3fff11 476 SMART SM00919 238 460 1.1E-120 T 28-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 CIG75_RS00045 a131eed6ce934807570d24f47b3fff11 476 SUPERFAMILY SSF53223 87 236 2.09E-55 T 28-03-2018 CIG75_RS00045 a131eed6ce934807570d24f47b3fff11 476 Pfam PF00390 Malic enzyme, N-terminal domain 95 226 1.2E-27 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CIG75_RS00045 a131eed6ce934807570d24f47b3fff11 476 ProSitePatterns PS00331 Malic enzymes signature. 234 250 - T 28-03-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 CIG75_RS00045 a131eed6ce934807570d24f47b3fff11 476 Pfam PF03949 Malic enzyme, NAD binding domain 240 459 1.8E-24 T 28-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 CIG75_RS00045 a131eed6ce934807570d24f47b3fff11 476 Gene3D G3DSA:3.40.50.10380 81 235 2.2E-40 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CIG75_RS00045 a131eed6ce934807570d24f47b3fff11 476 Gene3D G3DSA:3.40.50.720 236 476 2.6E-78 T 28-03-2018 CIG75_RS00045 a131eed6ce934807570d24f47b3fff11 476 PIRSF PIRSF000106 18 476 1.0E-92 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CIG75_RS09010 d4df15e92f33c105a061842a2afd2406 143 SUPERFAMILY SSF53800 2 121 1.16E-30 T 28-03-2018 CIG75_RS09010 d4df15e92f33c105a061842a2afd2406 143 Pfam PF01903 CbiX 11 114 1.5E-24 T 28-03-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 CIG75_RS09010 d4df15e92f33c105a061842a2afd2406 143 Gene3D G3DSA:3.40.50.1400 2 109 1.1E-27 T 28-03-2018 CIG75_RS14730 f752d96d21de3f6f7f06883f1d701ff2 698 Pfam PF01966 HD domain 487 630 7.3E-13 T 28-03-2018 IPR006674 HD domain CIG75_RS14730 f752d96d21de3f6f7f06883f1d701ff2 698 SMART SM00471 483 640 2.2E-11 T 28-03-2018 IPR003607 HD/PDEase domain CIG75_RS14730 f752d96d21de3f6f7f06883f1d701ff2 698 Gene3D G3DSA:1.10.3210.10 423 677 2.3E-31 T 28-03-2018 CIG75_RS14730 f752d96d21de3f6f7f06883f1d701ff2 698 TIGRFAM TIGR00277 HDIG: HDIG domain 484 582 8.2E-23 T 28-03-2018 IPR006675 HDIG domain CIG75_RS14730 f752d96d21de3f6f7f06883f1d701ff2 698 SUPERFAMILY SSF109604 486 682 4.4E-16 T 28-03-2018 CIG75_RS14730 f752d96d21de3f6f7f06883f1d701ff2 698 Pfam PF07697 7TM-HD extracellular 53 262 1.7E-40 T 28-03-2018 IPR011624 Metal-dependent phosphohydrolase, 7TM extracellular domain CIG75_RS14730 f752d96d21de3f6f7f06883f1d701ff2 698 Pfam PF07698 7TM receptor with intracellular HD hydrolase 269 462 1.7E-37 T 28-03-2018 IPR011621 Metal-dependent phosphohydrolase, 7TM intracellular domain CIG75_RS14190 d9d1a97f868c5819285857e46c63463a 318 Gene3D G3DSA:3.40.50.300 2 317 8.5E-38 T 28-03-2018 CIG75_RS14190 d9d1a97f868c5819285857e46c63463a 318 Pfam PF13614 AAA domain 4 205 1.4E-39 T 28-03-2018 IPR025669 AAA domain CIG75_RS14190 d9d1a97f868c5819285857e46c63463a 318 SUPERFAMILY SSF52540 5 211 1.41E-33 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS09855 0b530b137834506686871cc5e5f39803 182 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 54 73 - T 28-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CIG75_RS09855 0b530b137834506686871cc5e5f39803 182 Gene3D G3DSA:3.40.50.970 6 177 2.0E-17 T 28-03-2018 CIG75_RS09855 0b530b137834506686871cc5e5f39803 182 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 41 114 1.1E-16 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CIG75_RS09855 0b530b137834506686871cc5e5f39803 182 SUPERFAMILY SSF52518 5 161 4.83E-23 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CIG75_RS00975 164bc285aaf4a17422689499329f4490 149 Gene3D G3DSA:3.30.530.20 1 142 2.8E-20 T 28-03-2018 IPR023393 START-like domain CIG75_RS00975 164bc285aaf4a17422689499329f4490 149 SUPERFAMILY SSF55961 2 144 4.67E-23 T 28-03-2018 CIG75_RS00975 164bc285aaf4a17422689499329f4490 149 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 13 139 1.2E-12 T 28-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CIG75_RS01990 8503885d29ce663585efd6a4c0ec5d22 102 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 2 102 19.135 T 28-03-2018 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 CIG75_RS01990 8503885d29ce663585efd6a4c0ec5d22 102 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 9 95 8.5E-25 T 28-03-2018 CIG75_RS09700 07bc29fc532ab3b995302caca4dea515 120 Pfam PF02566 OsmC-like protein 9 105 1.9E-21 T 28-03-2018 IPR003718 OsmC/Ohr family CIG75_RS09700 07bc29fc532ab3b995302caca4dea515 120 SUPERFAMILY SSF82784 6 109 5.63E-34 T 28-03-2018 IPR003718 OsmC/Ohr family CIG75_RS09700 07bc29fc532ab3b995302caca4dea515 120 Gene3D G3DSA:3.30.300.20 1 115 1.3E-28 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CIG75_RS10095 538c2585f201c39e07939f0e8d43f46b 207 Pfam PF01726 LexA DNA binding domain 1 65 7.3E-29 T 28-03-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 CIG75_RS10095 538c2585f201c39e07939f0e8d43f46b 207 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 161 173 1.1E-11 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CIG75_RS10095 538c2585f201c39e07939f0e8d43f46b 207 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 132 143 1.1E-11 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CIG75_RS10095 538c2585f201c39e07939f0e8d43f46b 207 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 121 131 1.1E-11 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CIG75_RS10095 538c2585f201c39e07939f0e8d43f46b 207 Pfam PF00717 Peptidase S24-like 125 186 2.6E-17 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CIG75_RS10095 538c2585f201c39e07939f0e8d43f46b 207 SUPERFAMILY SSF51306 85 204 3.49E-37 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CIG75_RS10095 538c2585f201c39e07939f0e8d43f46b 207 Gene3D G3DSA:2.10.109.10 90 206 1.6E-25 T 28-03-2018 CIG75_RS10095 538c2585f201c39e07939f0e8d43f46b 207 Hamap MF_00015 LexA repressor [lexA]. 3 206 35.431 T 28-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 CIG75_RS10095 538c2585f201c39e07939f0e8d43f46b 207 SUPERFAMILY SSF46785 3 70 1.35E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS10095 538c2585f201c39e07939f0e8d43f46b 207 TIGRFAM TIGR00498 lexA: repressor LexA 1 205 3.8E-80 T 28-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 CIG75_RS10095 538c2585f201c39e07939f0e8d43f46b 207 Gene3D G3DSA:1.10.10.10 2 68 2.2E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS06325 b41b5e8db211bc7072be9f4c957dbdad 247 Gene3D G3DSA:1.10.1740.10 8 138 1.7E-14 T 28-03-2018 CIG75_RS06325 b41b5e8db211bc7072be9f4c957dbdad 247 PIRSF PIRSF038953 6 247 6.2E-67 T 28-03-2018 IPR014244 RNA polymerase sigma-I type CIG75_RS06325 b41b5e8db211bc7072be9f4c957dbdad 247 SUPERFAMILY SSF88946 22 104 7.85E-19 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS06325 b41b5e8db211bc7072be9f4c957dbdad 247 TIGRFAM TIGR02895 spore_sigI: RNA polymerase sigma-I factor 22 246 8.0E-80 T 28-03-2018 IPR014244 RNA polymerase sigma-I type CIG75_RS06325 b41b5e8db211bc7072be9f4c957dbdad 247 Gene3D G3DSA:1.10.10.10 139 238 0.035 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS06325 b41b5e8db211bc7072be9f4c957dbdad 247 Pfam PF07638 ECF sigma factor 15 173 7.9E-8 T 28-03-2018 IPR011517 RNA polymerase sigma-70 ECF-like CIG75_RS06325 b41b5e8db211bc7072be9f4c957dbdad 247 Hamap MF_02064 RNA polymerase sigma factor SigI [sigI]. 16 247 28.044 T 28-03-2018 IPR014244 RNA polymerase sigma-I type CIG75_RS06550 253f6b031a09b4616337da04ba154f8f 1649 SUPERFAMILY SSF56801 1030 1559 1.83E-146 T 28-03-2018 CIG75_RS06550 253f6b031a09b4616337da04ba154f8f 1649 Gene3D G3DSA:1.10.1200.10 1551 1624 1.7E-19 T 28-03-2018 CIG75_RS06550 253f6b031a09b4616337da04ba154f8f 1649 Pfam PF13193 AMP-binding enzyme C-terminal domain 1444 1519 4.2E-13 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS06550 253f6b031a09b4616337da04ba154f8f 1649 Gene3D G3DSA:3.30.300.30 1431 1550 3.5E-44 T 28-03-2018 CIG75_RS06550 253f6b031a09b4616337da04ba154f8f 1649 Gene3D G3DSA:3.40.50.980 1186 1344 6.2E-25 T 28-03-2018 CIG75_RS06550 253f6b031a09b4616337da04ba154f8f 1649 Gene3D G3DSA:2.30.38.10 1350 1429 2.1E-22 T 28-03-2018 CIG75_RS06550 253f6b031a09b4616337da04ba154f8f 1649 SUPERFAMILY SSF47336 462 535 4.97E-17 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS06550 253f6b031a09b4616337da04ba154f8f 1649 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1060 1460 8.5E-123 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS06550 253f6b031a09b4616337da04ba154f8f 1649 Gene3D G3DSA:3.40.50.980 1033 1185 9.9E-45 T 28-03-2018 CIG75_RS06550 253f6b031a09b4616337da04ba154f8f 1649 Gene3D G3DSA:1.10.1200.10 453 536 8.5E-20 T 28-03-2018 CIG75_RS06550 253f6b031a09b4616337da04ba154f8f 1649 Pfam PF00550 Phosphopantetheine attachment site 1548 1613 1.9E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS06550 253f6b031a09b4616337da04ba154f8f 1649 Pfam PF00550 Phosphopantetheine attachment site 473 534 1.8E-10 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS06550 253f6b031a09b4616337da04ba154f8f 1649 SMART SM00823 Phosphopantetheine attachment site 1547 1617 8.5E-10 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS06550 253f6b031a09b4616337da04ba154f8f 1649 SMART SM00823 Phosphopantetheine attachment site 470 539 0.014 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS06550 253f6b031a09b4616337da04ba154f8f 1649 SUPERFAMILY SSF47336 1539 1614 3.27E-17 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS06550 253f6b031a09b4616337da04ba154f8f 1649 SUPERFAMILY SSF52777 563 734 5.34E-51 T 28-03-2018 CIG75_RS06550 253f6b031a09b4616337da04ba154f8f 1649 Pfam PF00668 Condensation domain 7 435 6.3E-107 T 28-03-2018 IPR001242 Condensation domain CIG75_RS06550 253f6b031a09b4616337da04ba154f8f 1649 Pfam PF00668 Condensation domain 558 995 1.6E-119 T 28-03-2018 IPR001242 Condensation domain CIG75_RS06550 253f6b031a09b4616337da04ba154f8f 1649 SUPERFAMILY SSF52777 9 185 1.22E-47 T 28-03-2018 CIG75_RS06550 253f6b031a09b4616337da04ba154f8f 1649 SUPERFAMILY SSF52777 742 987 2.67E-67 T 28-03-2018 CIG75_RS06550 253f6b031a09b4616337da04ba154f8f 1649 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1180 1191 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS06550 253f6b031a09b4616337da04ba154f8f 1649 Pfam PF00501 AMP-binding enzyme 1040 1436 2.1E-92 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS06550 253f6b031a09b4616337da04ba154f8f 1649 SUPERFAMILY SSF52777 191 437 6.34E-64 T 28-03-2018 CIG75_RS06550 253f6b031a09b4616337da04ba154f8f 1649 Gene3D G3DSA:3.30.559.10 5 208 4.3E-44 T 28-03-2018 CIG75_RS06550 253f6b031a09b4616337da04ba154f8f 1649 Gene3D G3DSA:3.30.559.10 537 756 2.0E-50 T 28-03-2018 CIG75_RS09225 c1e9d6c26bd63dc4934882b2eb64d9ce 316 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 138 166 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CIG75_RS09225 c1e9d6c26bd63dc4934882b2eb64d9ce 316 Gene3D G3DSA:3.40.50.720 1 192 1.0E-34 T 28-03-2018 CIG75_RS09225 c1e9d6c26bd63dc4934882b2eb64d9ce 316 Gene3D G3DSA:3.90.25.10 193 315 3.0E-37 T 28-03-2018 CIG75_RS09225 c1e9d6c26bd63dc4934882b2eb64d9ce 316 SUPERFAMILY SSF51735 2 314 5.16E-86 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS09225 c1e9d6c26bd63dc4934882b2eb64d9ce 316 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 243 1.4E-55 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CIG75_RS09225 c1e9d6c26bd63dc4934882b2eb64d9ce 316 PRINTS PR01713 Nucleotide sugar epimerase signature 237 252 8.5E-11 T 28-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 CIG75_RS09225 c1e9d6c26bd63dc4934882b2eb64d9ce 316 PRINTS PR01713 Nucleotide sugar epimerase signature 215 230 8.5E-11 T 28-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 CIG75_RS09225 c1e9d6c26bd63dc4934882b2eb64d9ce 316 PRINTS PR01713 Nucleotide sugar epimerase signature 276 293 8.5E-11 T 28-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 CIG75_RS09225 c1e9d6c26bd63dc4934882b2eb64d9ce 316 PRINTS PR01713 Nucleotide sugar epimerase signature 32 48 8.5E-11 T 28-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 CIG75_RS15575 bd71bba66b2428266453d3c6f639844f 149 Gene3D G3DSA:3.40.630.30 1 133 6.5E-24 T 28-03-2018 CIG75_RS15575 bd71bba66b2428266453d3c6f639844f 149 Pfam PF00583 Acetyltransferase (GNAT) family 28 129 4.4E-14 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CIG75_RS15575 bd71bba66b2428266453d3c6f639844f 149 SUPERFAMILY SSF55729 2 129 1.37E-24 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CIG75_RS18835 9f2bc2a533eacc47a2f76111e8098597 418 Pfam PF07833 Copper amine oxidase N-terminal domain 57 143 1.1E-25 T 28-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CIG75_RS18835 9f2bc2a533eacc47a2f76111e8098597 418 Pfam PF00704 Glycosyl hydrolases family 18 213 377 1.5E-10 T 28-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 CIG75_RS18835 9f2bc2a533eacc47a2f76111e8098597 418 Gene3D G3DSA:3.20.20.80 138 406 2.6E-31 T 28-03-2018 CIG75_RS18835 9f2bc2a533eacc47a2f76111e8098597 418 Gene3D G3DSA:3.30.457.10 22 67 1.2E-6 T 28-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CIG75_RS18835 9f2bc2a533eacc47a2f76111e8098597 418 Gene3D G3DSA:3.30.457.10 68 137 1.4E-22 T 28-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CIG75_RS18835 9f2bc2a533eacc47a2f76111e8098597 418 SUPERFAMILY SSF55383 60 143 4.12E-22 T 28-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CIG75_RS18835 9f2bc2a533eacc47a2f76111e8098597 418 SUPERFAMILY SSF51445 170 396 4.95E-30 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CIG75_RS06850 dea3843623f24aadfe676c7e933937f1 525 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 362 505 2.1E-25 T 28-03-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain CIG75_RS06850 dea3843623f24aadfe676c7e933937f1 525 PIRSF PIRSF038958 2 525 4.5E-104 T 28-03-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type CIG75_RS06850 dea3843623f24aadfe676c7e933937f1 525 Pfam PF01943 Polysaccharide biosynthesis protein 7 310 2.2E-29 T 28-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 CIG75_RS17730 735c7b02c7bea7da2d960a0ea3081d9b 338 PRINTS PR00990 Ribokinase signature 185 200 8.5E-9 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CIG75_RS17730 735c7b02c7bea7da2d960a0ea3081d9b 338 PRINTS PR00990 Ribokinase signature 29 48 8.5E-9 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CIG75_RS17730 735c7b02c7bea7da2d960a0ea3081d9b 338 PRINTS PR00990 Ribokinase signature 224 235 8.5E-9 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CIG75_RS17730 735c7b02c7bea7da2d960a0ea3081d9b 338 Pfam PF00294 pfkB family carbohydrate kinase 3 314 8.1E-70 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB CIG75_RS17730 735c7b02c7bea7da2d960a0ea3081d9b 338 Gene3D G3DSA:3.40.1190.20 2 327 7.5E-77 T 28-03-2018 IPR029056 Ribokinase-like CIG75_RS17730 735c7b02c7bea7da2d960a0ea3081d9b 338 SUPERFAMILY SSF53613 1 322 3.9E-85 T 28-03-2018 IPR029056 Ribokinase-like CIG75_RS12995 83e7067acd3680b331b7d97b262cbd99 451 Pfam PF00589 Phage integrase family 263 430 1.4E-18 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CIG75_RS12995 83e7067acd3680b331b7d97b262cbd99 451 Gene3D G3DSA:1.10.150.130 78 193 5.8E-15 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CIG75_RS12995 83e7067acd3680b331b7d97b262cbd99 451 Gene3D G3DSA:1.10.443.10 244 439 4.1E-34 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CIG75_RS12995 83e7067acd3680b331b7d97b262cbd99 451 SUPERFAMILY SSF56349 84 209 2.12E-12 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CIG75_RS12995 83e7067acd3680b331b7d97b262cbd99 451 SUPERFAMILY SSF56349 260 436 3.24E-36 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CIG75_RS12995 83e7067acd3680b331b7d97b262cbd99 451 ProSitePatterns PS00221 MIP family signature. 417 425 - T 28-03-2018 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CIG75_RS11840 46f6615f32a1ef9e4dfa11201c44ca80 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.1E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS11840 46f6615f32a1ef9e4dfa11201c44ca80 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 1.1E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS11840 46f6615f32a1ef9e4dfa11201c44ca80 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 1.1E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS11840 46f6615f32a1ef9e4dfa11201c44ca80 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 1.1E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS11840 46f6615f32a1ef9e4dfa11201c44ca80 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 1.1E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS11840 46f6615f32a1ef9e4dfa11201c44ca80 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 1.1E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS11840 46f6615f32a1ef9e4dfa11201c44ca80 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 2.2E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS11840 46f6615f32a1ef9e4dfa11201c44ca80 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 2.2E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS11840 46f6615f32a1ef9e4dfa11201c44ca80 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 2.2E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS11840 46f6615f32a1ef9e4dfa11201c44ca80 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 250 2.4E-68 T 28-03-2018 CIG75_RS11840 46f6615f32a1ef9e4dfa11201c44ca80 252 Gene3D G3DSA:3.40.50.720 40 252 1.1E-58 T 28-03-2018 CIG75_RS11840 46f6615f32a1ef9e4dfa11201c44ca80 252 Gene3D G3DSA:3.40.50.720 1 39 9.5E-11 T 28-03-2018 CIG75_RS11840 46f6615f32a1ef9e4dfa11201c44ca80 252 SUPERFAMILY SSF51735 4 251 2.08E-79 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS11840 46f6615f32a1ef9e4dfa11201c44ca80 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CIG75_RS07680 f794170b2c0113cb0d43ab8ccaffcb67 222 Pfam PF04012 PspA/IM30 family 3 219 5.6E-54 T 28-03-2018 IPR007157 PspA/IM30 CIG75_RS07680 f794170b2c0113cb0d43ab8ccaffcb67 222 Gene3D G3DSA:3.90.20.10 98 222 0.065 T 28-03-2018 CIG75_RS07680 f794170b2c0113cb0d43ab8ccaffcb67 222 Gene3D G3DSA:3.90.20.10 4 97 0.066 T 28-03-2018 CIG75_RS13560 94c80c818a8e162239776ea6c7a302ea 330 Gene3D G3DSA:1.10.1040.10 187 314 5.7E-35 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CIG75_RS13560 94c80c818a8e162239776ea6c7a302ea 330 Pfam PF02558 Ketopantoate reductase PanE/ApbA 12 162 2.4E-37 T 28-03-2018 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 CIG75_RS13560 94c80c818a8e162239776ea6c7a302ea 330 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 187 308 1.6E-33 T 28-03-2018 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 CIG75_RS13560 94c80c818a8e162239776ea6c7a302ea 330 SUPERFAMILY SSF51735 10 176 5.9E-26 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS13560 94c80c818a8e162239776ea6c7a302ea 330 SUPERFAMILY SSF48179 187 309 2.35E-29 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CIG75_RS13560 94c80c818a8e162239776ea6c7a302ea 330 Gene3D G3DSA:3.40.50.720 10 185 1.2E-26 T 28-03-2018 CIG75_RS13560 94c80c818a8e162239776ea6c7a302ea 330 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 11 310 1.6E-81 T 28-03-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0015940|GO:0016491|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 CIG75_RS00425 18b2c57f6adde3cff6d2e1c10937a5ca 338 SMART SM00387 228 338 3.7E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS00425 18b2c57f6adde3cff6d2e1c10937a5ca 338 Gene3D G3DSA:3.30.565.10 189 337 1.3E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS00425 18b2c57f6adde3cff6d2e1c10937a5ca 338 SUPERFAMILY SSF55874 172 333 4.06E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS00425 18b2c57f6adde3cff6d2e1c10937a5ca 338 Pfam PF00672 HAMP domain 55 103 1.6E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CIG75_RS00425 18b2c57f6adde3cff6d2e1c10937a5ca 338 SUPERFAMILY SSF47384 98 180 7.06E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CIG75_RS00425 18b2c57f6adde3cff6d2e1c10937a5ca 338 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 229 333 2.5E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS00425 18b2c57f6adde3cff6d2e1c10937a5ca 338 SUPERFAMILY SSF158472 55 105 4.71E-8 T 28-03-2018 CIG75_RS00425 18b2c57f6adde3cff6d2e1c10937a5ca 338 SMART SM00304 55 107 6.3E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CIG75_RS00425 18b2c57f6adde3cff6d2e1c10937a5ca 338 Gene3D G3DSA:1.10.287.130 88 178 6.7E-13 T 28-03-2018 CIG75_RS00425 18b2c57f6adde3cff6d2e1c10937a5ca 338 PRINTS PR00344 Bacterial sensor protein C-terminal signature 266 280 3.5E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS00425 18b2c57f6adde3cff6d2e1c10937a5ca 338 PRINTS PR00344 Bacterial sensor protein C-terminal signature 301 319 3.5E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS00425 18b2c57f6adde3cff6d2e1c10937a5ca 338 PRINTS PR00344 Bacterial sensor protein C-terminal signature 284 294 3.5E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS00425 18b2c57f6adde3cff6d2e1c10937a5ca 338 SMART SM00388 115 182 2.5E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CIG75_RS00425 18b2c57f6adde3cff6d2e1c10937a5ca 338 Pfam PF00512 His Kinase A (phospho-acceptor) domain 117 180 1.3E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CIG75_RS18670 ec54e0c1057863805e985f234a4d636e 712 SUPERFAMILY SSF55326 373 537 1.23E-54 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CIG75_RS18670 ec54e0c1057863805e985f234a4d636e 712 SUPERFAMILY SSF56042 175 398 1.15E-54 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CIG75_RS18670 ec54e0c1057863805e985f234a4d636e 712 Gene3D G3DSA:3.90.650.10 537 712 1.8E-32 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CIG75_RS18670 ec54e0c1057863805e985f234a4d636e 712 PIRSF PIRSF001587 1 712 0.0 T 28-03-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CIG75_RS18670 ec54e0c1057863805e985f234a4d636e 712 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 712 311.248 T 28-03-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CIG75_RS18670 ec54e0c1057863805e985f234a4d636e 712 Gene3D G3DSA:3.30.1330.10 387 535 1.1E-47 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CIG75_RS18670 ec54e0c1057863805e985f234a4d636e 712 Gene3D G3DSA:3.30.1330.10 15 152 8.7E-47 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CIG75_RS18670 ec54e0c1057863805e985f234a4d636e 712 SUPERFAMILY SSF56042 540 711 2.54E-38 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CIG75_RS18670 ec54e0c1057863805e985f234a4d636e 712 Pfam PF02769 AIR synthase related protein, C-terminal domain 544 679 3.1E-16 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CIG75_RS18670 ec54e0c1057863805e985f234a4d636e 712 Pfam PF02769 AIR synthase related protein, C-terminal domain 176 327 2.9E-34 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CIG75_RS18670 ec54e0c1057863805e985f234a4d636e 712 Pfam PF00586 AIR synthase related protein, N-terminal domain 413 530 3.2E-22 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CIG75_RS18670 ec54e0c1057863805e985f234a4d636e 712 Pfam PF00586 AIR synthase related protein, N-terminal domain 55 163 7.5E-24 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CIG75_RS18670 ec54e0c1057863805e985f234a4d636e 712 SUPERFAMILY SSF55326 8 169 1.27E-49 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CIG75_RS18670 ec54e0c1057863805e985f234a4d636e 712 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 1 711 1.7E-290 T 28-03-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CIG75_RS18670 ec54e0c1057863805e985f234a4d636e 712 Gene3D G3DSA:3.90.650.10 153 344 1.1E-34 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CIG75_RS06345 25d4d7603396d0da0996f069cae3a4ea 341 SUPERFAMILY SSF111337 1 340 3.79E-143 T 28-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 CIG75_RS06345 25d4d7603396d0da0996f069cae3a4ea 341 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 1 341 47.564 T 28-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 CIG75_RS06345 25d4d7603396d0da0996f069cae3a4ea 341 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 1 340 3.9E-143 T 28-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 CIG75_RS06345 25d4d7603396d0da0996f069cae3a4ea 341 Gene3D G3DSA:3.40.1780.10 173 341 7.8E-69 T 28-03-2018 CIG75_RS06345 25d4d7603396d0da0996f069cae3a4ea 341 Gene3D G3DSA:3.40.1780.10 1 134 4.0E-44 T 28-03-2018 CIG75_RS06345 25d4d7603396d0da0996f069cae3a4ea 341 Pfam PF02547 Queuosine biosynthesis protein 4 340 1.0E-146 T 28-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 CIG75_RS17360 b13651c5791e459a8813bf533d063eff 312 Gene3D G3DSA:3.40.50.300 137 309 1.3E-44 T 28-03-2018 CIG75_RS17360 b13651c5791e459a8813bf533d063eff 312 SUPERFAMILY SSF53795 136 299 1.86E-40 T 28-03-2018 CIG75_RS17360 b13651c5791e459a8813bf533d063eff 312 Hamap MF_01249 HPr kinase/phosphorylase [hprK]. 4 308 39.969 T 28-03-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 CIG75_RS17360 b13651c5791e459a8813bf533d063eff 312 Pfam PF02603 HPr Serine kinase N terminus 5 128 2.3E-34 T 28-03-2018 IPR011126 HPr(Ser) kinase/phosphorylase, N-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 CIG75_RS17360 b13651c5791e459a8813bf533d063eff 312 Gene3D G3DSA:3.40.1390.20 4 134 8.7E-38 T 28-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like CIG75_RS17360 b13651c5791e459a8813bf533d063eff 312 TIGRFAM TIGR00679 hpr-ser: HPr(Ser) kinase/phosphatase 5 305 5.8E-114 T 28-03-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 CIG75_RS17360 b13651c5791e459a8813bf533d063eff 312 Pfam PF07475 HPr Serine kinase C-terminal domain 132 300 1.2E-73 T 28-03-2018 IPR011104 HPr kinase/phosphorylase, C-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 CIG75_RS17360 b13651c5791e459a8813bf533d063eff 312 SUPERFAMILY SSF75138 6 133 1.57E-31 T 28-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like CIG75_RS16280 67752f0cbd4b51cf3959c014bce8c74a 484 Gene3D G3DSA:3.40.630.10 163 484 8.7E-119 T 28-03-2018 CIG75_RS16280 67752f0cbd4b51cf3959c014bce8c74a 484 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 5 484 32.36 T 28-03-2018 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 CIG75_RS16280 67752f0cbd4b51cf3959c014bce8c74a 484 SUPERFAMILY SSF53187 166 480 4.92E-105 T 28-03-2018 CIG75_RS16280 67752f0cbd4b51cf3959c014bce8c74a 484 PRINTS PR00481 Cytosol aminopeptidase signature 328 348 3.3E-48 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CIG75_RS16280 67752f0cbd4b51cf3959c014bce8c74a 484 PRINTS PR00481 Cytosol aminopeptidase signature 356 371 3.3E-48 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CIG75_RS16280 67752f0cbd4b51cf3959c014bce8c74a 484 PRINTS PR00481 Cytosol aminopeptidase signature 306 327 3.3E-48 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CIG75_RS16280 67752f0cbd4b51cf3959c014bce8c74a 484 PRINTS PR00481 Cytosol aminopeptidase signature 247 264 3.3E-48 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CIG75_RS16280 67752f0cbd4b51cf3959c014bce8c74a 484 PRINTS PR00481 Cytosol aminopeptidase signature 269 290 3.3E-48 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CIG75_RS16280 67752f0cbd4b51cf3959c014bce8c74a 484 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 21 137 4.3E-21 T 28-03-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CIG75_RS16280 67752f0cbd4b51cf3959c014bce8c74a 484 SUPERFAMILY SSF52949 7 169 2.24E-23 T 28-03-2018 CIG75_RS16280 67752f0cbd4b51cf3959c014bce8c74a 484 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 170 475 1.7E-107 T 28-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CIG75_RS16280 67752f0cbd4b51cf3959c014bce8c74a 484 Gene3D G3DSA:3.40.220.10 17 162 2.2E-28 T 28-03-2018 CIG75_RS12445 f4607bba9f5c549017f5fce7c8f25c74 296 Pfam PF03313 Serine dehydratase alpha chain 16 276 2.9E-72 T 28-03-2018 IPR005130 Serine dehydratase-like, alpha subunit CIG75_RS12445 f4607bba9f5c549017f5fce7c8f25c74 296 TIGRFAM TIGR00718 sda_alpha: L-serine dehydratase, iron-sulfur-dependent, alpha subunit 4 291 6.9E-107 T 28-03-2018 IPR004642 Serine dehydratase, alpha subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CIG75_RS12445 f4607bba9f5c549017f5fce7c8f25c74 296 Gene3D G3DSA:1.10.4100.10 22 280 3.4E-29 T 28-03-2018 CIG75_RS14710 1299cc2ef362a810c1679dc9879ac39c 305 SUPERFAMILY SSF52540 15 211 1.38E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS14710 1299cc2ef362a810c1679dc9879ac39c 305 Pfam PF07650 KH domain 213 291 5.2E-21 T 28-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CIG75_RS14710 1299cc2ef362a810c1679dc9879ac39c 305 Pfam PF01926 50S ribosome-binding GTPase 15 130 4.1E-26 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CIG75_RS14710 1299cc2ef362a810c1679dc9879ac39c 305 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 173 4.2E-31 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CIG75_RS14710 1299cc2ef362a810c1679dc9879ac39c 305 Gene3D G3DSA:3.30.300.20 190 305 4.4E-46 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CIG75_RS14710 1299cc2ef362a810c1679dc9879ac39c 305 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 15 35 9.4E-6 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CIG75_RS14710 1299cc2ef362a810c1679dc9879ac39c 305 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 82 100 9.4E-6 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CIG75_RS14710 1299cc2ef362a810c1679dc9879ac39c 305 Hamap MF_00367 GTPase Era [era]. 10 302 39.606 T 28-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS14710 1299cc2ef362a810c1679dc9879ac39c 305 Gene3D G3DSA:3.40.50.300 1 60 6.1E-17 T 28-03-2018 CIG75_RS14710 1299cc2ef362a810c1679dc9879ac39c 305 TIGRFAM TIGR00436 era: GTP-binding protein Era 13 285 9.2E-102 T 28-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS14710 1299cc2ef362a810c1679dc9879ac39c 305 SUPERFAMILY SSF54814 186 302 2.16E-43 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CIG75_RS14710 1299cc2ef362a810c1679dc9879ac39c 305 Gene3D G3DSA:3.40.50.300 61 179 1.2E-19 T 28-03-2018 CIG75_RS02800 207a9c02cddb22f55567dda8e7e109a6 1623 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 311 427 2.9E-39 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CIG75_RS02800 207a9c02cddb22f55567dda8e7e109a6 1623 Pfam PF00550 Phosphopantetheine attachment site 1512 1570 1.4E-9 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS02800 207a9c02cddb22f55567dda8e7e109a6 1623 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 39 302 3.1E-68 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CIG75_RS02800 207a9c02cddb22f55567dda8e7e109a6 1623 Gene3D G3DSA:3.40.47.10 31 313 5.6E-72 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS02800 207a9c02cddb22f55567dda8e7e109a6 1623 Gene3D G3DSA:3.40.47.10 317 478 3.1E-53 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS02800 207a9c02cddb22f55567dda8e7e109a6 1623 Pfam PF08659 KR domain 1188 1381 4.7E-48 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS02800 207a9c02cddb22f55567dda8e7e109a6 1623 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1529 1544 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS02800 207a9c02cddb22f55567dda8e7e109a6 1623 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 430 542 1.4E-12 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS02800 207a9c02cddb22f55567dda8e7e109a6 1623 Gene3D G3DSA:3.10.129.10 678 802 3.7E-15 T 28-03-2018 CIG75_RS02800 207a9c02cddb22f55567dda8e7e109a6 1623 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1188 1383 4.6E-42 T 28-03-2018 CIG75_RS02800 207a9c02cddb22f55567dda8e7e109a6 1623 Gene3D G3DSA:1.10.1200.10 1497 1600 1.8E-13 T 28-03-2018 CIG75_RS02800 207a9c02cddb22f55567dda8e7e109a6 1623 SMART SM00826 676 815 3.7E-13 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS02800 207a9c02cddb22f55567dda8e7e109a6 1623 SUPERFAMILY SSF51735 956 1174 3.67E-11 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS02800 207a9c02cddb22f55567dda8e7e109a6 1623 Pfam PF14765 Polyketide synthase dehydratase 676 944 6.3E-52 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS02800 207a9c02cddb22f55567dda8e7e109a6 1623 Gene3D G3DSA:3.40.50.720 1180 1460 3.9E-37 T 28-03-2018 CIG75_RS02800 207a9c02cddb22f55567dda8e7e109a6 1623 SUPERFAMILY SSF53901 36 424 1.46E-86 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS02800 207a9c02cddb22f55567dda8e7e109a6 1623 SUPERFAMILY SSF47336 1500 1592 4.97E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS02800 207a9c02cddb22f55567dda8e7e109a6 1623 SMART SM00825 Beta-ketoacyl synthase 41 480 1.1E-159 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CIG75_RS02800 207a9c02cddb22f55567dda8e7e109a6 1623 SMART SM00823 Phosphopantetheine attachment site 1505 1574 7.2E-4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS02800 207a9c02cddb22f55567dda8e7e109a6 1623 SUPERFAMILY SSF51735 1186 1385 6.86E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS02800 207a9c02cddb22f55567dda8e7e109a6 1623 SUPERFAMILY SSF51735 1419 1451 6.86E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS18065 1064f3f5eb924d559662d800fb6c1fd7 472 PIRSF PIRSF000350 2 463 1.2E-99 T 28-03-2018 CIG75_RS18065 1064f3f5eb924d559662d800fb6c1fd7 472 SUPERFAMILY SSF55424 345 468 1.36E-38 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CIG75_RS18065 1064f3f5eb924d559662d800fb6c1fd7 472 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 11 330 2.7E-68 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS18065 1064f3f5eb924d559662d800fb6c1fd7 472 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 12 31 2.9E-39 T 28-03-2018 CIG75_RS18065 1064f3f5eb924d559662d800fb6c1fd7 472 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 140 158 2.9E-39 T 28-03-2018 CIG75_RS18065 1064f3f5eb924d559662d800fb6c1fd7 472 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 295 317 2.9E-39 T 28-03-2018 CIG75_RS18065 1064f3f5eb924d559662d800fb6c1fd7 472 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 179 197 2.9E-39 T 28-03-2018 CIG75_RS18065 1064f3f5eb924d559662d800fb6c1fd7 472 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 266 282 2.9E-39 T 28-03-2018 CIG75_RS18065 1064f3f5eb924d559662d800fb6c1fd7 472 Gene3D G3DSA:3.50.50.60 161 216 3.4E-9 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS18065 1064f3f5eb924d559662d800fb6c1fd7 472 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 44 54 - T 28-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 CIG75_RS18065 1064f3f5eb924d559662d800fb6c1fd7 472 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 350 457 9.2E-34 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CIG75_RS18065 1064f3f5eb924d559662d800fb6c1fd7 472 Gene3D G3DSA:3.50.50.60 6 160 5.2E-30 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS18065 1064f3f5eb924d559662d800fb6c1fd7 472 Gene3D G3DSA:3.50.50.60 217 340 3.2E-24 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS18065 1064f3f5eb924d559662d800fb6c1fd7 472 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 11 33 4.8E-76 T 28-03-2018 CIG75_RS18065 1064f3f5eb924d559662d800fb6c1fd7 472 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 345 366 4.8E-76 T 28-03-2018 CIG75_RS18065 1064f3f5eb924d559662d800fb6c1fd7 472 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 143 152 4.8E-76 T 28-03-2018 CIG75_RS18065 1064f3f5eb924d559662d800fb6c1fd7 472 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 43 58 4.8E-76 T 28-03-2018 CIG75_RS18065 1064f3f5eb924d559662d800fb6c1fd7 472 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 267 281 4.8E-76 T 28-03-2018 CIG75_RS18065 1064f3f5eb924d559662d800fb6c1fd7 472 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 179 204 4.8E-76 T 28-03-2018 CIG75_RS18065 1064f3f5eb924d559662d800fb6c1fd7 472 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 310 317 4.8E-76 T 28-03-2018 CIG75_RS18065 1064f3f5eb924d559662d800fb6c1fd7 472 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 410 425 4.8E-76 T 28-03-2018 CIG75_RS18065 1064f3f5eb924d559662d800fb6c1fd7 472 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 432 452 4.8E-76 T 28-03-2018 CIG75_RS18065 1064f3f5eb924d559662d800fb6c1fd7 472 SUPERFAMILY SSF51905 8 339 4.64E-66 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS18065 1064f3f5eb924d559662d800fb6c1fd7 472 Gene3D G3DSA:3.30.390.30 341 466 1.2E-40 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CIG75_RS18065 1064f3f5eb924d559662d800fb6c1fd7 472 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 10 467 1.2E-157 T 28-03-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 CIG75_RS17420 25fc22191ebf2e3a2cc913d0734e8768 228 Gene3D G3DSA:3.40.50.300 1 223 5.1E-69 T 28-03-2018 CIG75_RS17420 25fc22191ebf2e3a2cc913d0734e8768 228 SMART SM00382 27 221 4.0E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS17420 25fc22191ebf2e3a2cc913d0734e8768 228 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS17420 25fc22191ebf2e3a2cc913d0734e8768 228 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 1 214 1.5E-91 T 28-03-2018 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 CIG75_RS17420 25fc22191ebf2e3a2cc913d0734e8768 228 SUPERFAMILY SSF52540 1 219 3.0E-74 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS17420 25fc22191ebf2e3a2cc913d0734e8768 228 Pfam PF00005 ABC transporter 18 165 6.8E-37 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS12825 55387865cf082530ca366bc110cd721b 346 Pfam PF00145 C-5 cytosine-specific DNA methylase 26 207 3.9E-37 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CIG75_RS12825 55387865cf082530ca366bc110cd721b 346 SUPERFAMILY SSF53335 23 337 1.04E-50 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CIG75_RS12825 55387865cf082530ca366bc110cd721b 346 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 188 201 1.2E-10 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CIG75_RS12825 55387865cf082530ca366bc110cd721b 346 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 22 38 1.2E-10 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CIG75_RS12825 55387865cf082530ca366bc110cd721b 346 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 142 156 1.2E-10 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CIG75_RS12825 55387865cf082530ca366bc110cd721b 346 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 27 205 4.1E-34 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CIG75_RS12825 55387865cf082530ca366bc110cd721b 346 Gene3D G3DSA:3.40.50.150 22 273 3.0E-45 T 28-03-2018 CIG75_RS14775 5082f890d013a64038bd4d1300ad5d5f 403 SUPERFAMILY SSF53335 78 395 9.33E-69 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CIG75_RS14775 5082f890d013a64038bd4d1300ad5d5f 403 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 166 370 1.2E-22 T 28-03-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 CIG75_RS14775 5082f890d013a64038bd4d1300ad5d5f 403 Gene3D G3DSA:2.30.130.10 1 69 2.5E-25 T 28-03-2018 IPR002478 PUA domain GO:0003723 CIG75_RS14775 5082f890d013a64038bd4d1300ad5d5f 403 SMART SM00359 2 87 3.1E-11 T 28-03-2018 IPR002478 PUA domain GO:0003723 CIG75_RS14775 5082f890d013a64038bd4d1300ad5d5f 403 Gene3D G3DSA:3.40.50.150 178 403 6.0E-40 T 28-03-2018 CIG75_RS14775 5082f890d013a64038bd4d1300ad5d5f 403 SUPERFAMILY SSF88697 2 71 1.44E-17 T 28-03-2018 IPR015947 PUA-like domain CIG75_RS14775 5082f890d013a64038bd4d1300ad5d5f 403 Gene3D G3DSA:3.30.750.80 73 177 1.9E-38 T 28-03-2018 CIG75_RS18545 d854099ba9ba95988c5a30f86b7f508e 224 Pfam PF00072 Response regulator receiver domain 4 112 3.1E-32 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CIG75_RS18545 d854099ba9ba95988c5a30f86b7f508e 224 Gene3D G3DSA:3.40.50.2300 1 119 1.6E-39 T 28-03-2018 CIG75_RS18545 d854099ba9ba95988c5a30f86b7f508e 224 SMART SM00448 2 112 1.2E-43 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CIG75_RS18545 d854099ba9ba95988c5a30f86b7f508e 224 SMART SM00862 145 220 1.1E-23 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CIG75_RS18545 d854099ba9ba95988c5a30f86b7f508e 224 SUPERFAMILY SSF52172 1 166 3.7E-45 T 28-03-2018 IPR011006 CheY-like superfamily CIG75_RS18545 d854099ba9ba95988c5a30f86b7f508e 224 Gene3D G3DSA:1.10.10.10 120 224 3.6E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS18545 d854099ba9ba95988c5a30f86b7f508e 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 220 2.4E-23 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CIG75_RS05225 1080f0dd774242d84f183908d4a21b53 293 SUPERFAMILY SSF51735 1 262 3.37E-63 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS05225 1080f0dd774242d84f183908d4a21b53 293 Pfam PF13460 NAD(P)H-binding 7 149 3.1E-28 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS05225 1080f0dd774242d84f183908d4a21b53 293 Gene3D G3DSA:3.40.50.720 1 290 1.6E-49 T 28-03-2018 CIG75_RS13070 9c620c64ea07f5a1f5de54002e3111be 236 SUPERFAMILY SSF57716 91 126 8.27E-8 T 28-03-2018 CIG75_RS13070 9c620c64ea07f5a1f5de54002e3111be 236 SUPERFAMILY SSF109635 3 90 2.62E-11 T 28-03-2018 CIG75_RS13070 9c620c64ea07f5a1f5de54002e3111be 236 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 90 123 4.2E-12 T 28-03-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 CIG75_RS13070 9c620c64ea07f5a1f5de54002e3111be 236 TIGRFAM TIGR02890 bacill_yteA: regulatory protein, yteA family 6 169 6.5E-53 T 28-03-2018 IPR014240 Regulatory protein, YteA family CIG75_RS12400 90db3b4fb6eb7988ef44485fdd17e27e 357 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 247 347 3.3E-7 T 28-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 CIG75_RS12400 90db3b4fb6eb7988ef44485fdd17e27e 357 Gene3D G3DSA:3.30.230.10 45 357 4.7E-36 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CIG75_RS12400 90db3b4fb6eb7988ef44485fdd17e27e 357 Pfam PF13180 PDZ domain 151 204 3.0E-8 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CIG75_RS12400 90db3b4fb6eb7988ef44485fdd17e27e 357 SUPERFAMILY SSF50156 138 209 1.86E-9 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CIG75_RS12400 90db3b4fb6eb7988ef44485fdd17e27e 357 SUPERFAMILY SSF54211 244 350 5.31E-18 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CIG75_RS08050 f1e07f506e6fd207bb01f799c1908c8d 291 Pfam PF14885 Hypothetical glycosyl hydrolase family 15 111 270 7.1E-10 T 28-03-2018 IPR029455 Hypothetical glycosyl hydrolase family 15 CIG75_RS08050 f1e07f506e6fd207bb01f799c1908c8d 291 Gene3D G3DSA:3.20.20.70 28 291 2.5E-34 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CIG75_RS08050 f1e07f506e6fd207bb01f799c1908c8d 291 SUPERFAMILY SSF51445 46 261 5.47E-15 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CIG75_RS11335 acaaeb17b06ca32cf8055bed54b7468c 1781 Gene3D G3DSA:3.30.450.40 1321 1500 2.3E-25 T 28-03-2018 IPR029016 GAF domain-like CIG75_RS11335 acaaeb17b06ca32cf8055bed54b7468c 1781 Pfam PF13191 AAA ATPase domain 298 486 1.7E-38 T 28-03-2018 CIG75_RS11335 acaaeb17b06ca32cf8055bed54b7468c 1781 SUPERFAMILY SSF55073 1525 1706 4.08E-51 T 28-03-2018 IPR029787 Nucleotide cyclase CIG75_RS11335 acaaeb17b06ca32cf8055bed54b7468c 1781 Gene3D G3DSA:1.10.510.10 103 281 2.0E-38 T 28-03-2018 CIG75_RS11335 acaaeb17b06ca32cf8055bed54b7468c 1781 Gene3D G3DSA:1.25.40.10 1712 1766 0.17 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS11335 acaaeb17b06ca32cf8055bed54b7468c 1781 SUPERFAMILY SSF48452 765 854 1.44E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS11335 acaaeb17b06ca32cf8055bed54b7468c 1781 Gene3D G3DSA:3.30.70.1230 1524 1711 8.0E-43 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CIG75_RS11335 acaaeb17b06ca32cf8055bed54b7468c 1781 SMART SM00044 1499 1688 1.4E-6 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CIG75_RS11335 acaaeb17b06ca32cf8055bed54b7468c 1781 SUPERFAMILY SSF56112 4 268 3.42E-61 T 28-03-2018 IPR011009 Protein kinase-like domain CIG75_RS11335 acaaeb17b06ca32cf8055bed54b7468c 1781 Pfam PF00069 Protein kinase domain 7 258 1.4E-39 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CIG75_RS11335 acaaeb17b06ca32cf8055bed54b7468c 1781 SMART SM00065 1340 1493 8.4E-13 T 28-03-2018 IPR003018 GAF domain GO:0005515 CIG75_RS11335 acaaeb17b06ca32cf8055bed54b7468c 1781 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 124 136 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CIG75_RS11335 acaaeb17b06ca32cf8055bed54b7468c 1781 Gene3D G3DSA:1.25.40.10 737 1310 2.2E-22 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS11335 acaaeb17b06ca32cf8055bed54b7468c 1781 SUPERFAMILY SSF52540 295 574 1.62E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS11335 acaaeb17b06ca32cf8055bed54b7468c 1781 SMART SM00220 7 267 1.6E-35 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CIG75_RS11335 acaaeb17b06ca32cf8055bed54b7468c 1781 SUPERFAMILY SSF55781 1328 1497 3.49E-23 T 28-03-2018 IPR029016 GAF domain-like CIG75_RS11335 acaaeb17b06ca32cf8055bed54b7468c 1781 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 1527 1700 1.0E-32 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CIG75_RS11335 acaaeb17b06ca32cf8055bed54b7468c 1781 Gene3D G3DSA:3.40.50.300 289 518 2.8E-9 T 28-03-2018 CIG75_RS11335 acaaeb17b06ca32cf8055bed54b7468c 1781 Gene3D G3DSA:3.30.200.20 3 102 1.7E-12 T 28-03-2018 CIG75_RS11335 acaaeb17b06ca32cf8055bed54b7468c 1781 Pfam PF01590 GAF domain 1341 1483 1.9E-12 T 28-03-2018 IPR003018 GAF domain GO:0005515 CIG75_RS11760 d75f71d40525cbed9200ee8518bbae74 747 SUPERFAMILY SSF46915 227 327 2.88E-21 T 28-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CIG75_RS11760 d75f71d40525cbed9200ee8518bbae74 747 Gene3D G3DSA:1.10.10.400 249 309 9.3E-20 T 28-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CIG75_RS11760 d75f71d40525cbed9200ee8518bbae74 747 Gene3D G3DSA:3.30.230.70 310 564 1.5E-60 T 28-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CIG75_RS11760 d75f71d40525cbed9200ee8518bbae74 747 Gene3D G3DSA:3.30.1370.10 565 626 1.4E-13 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CIG75_RS11760 d75f71d40525cbed9200ee8518bbae74 747 Pfam PF00013 KH domain 557 613 5.2E-8 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CIG75_RS11760 d75f71d40525cbed9200ee8518bbae74 747 SUPERFAMILY SSF55666 135 224 4.32E-28 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CIG75_RS11760 d75f71d40525cbed9200ee8518bbae74 747 SUPERFAMILY SSF54211 6 141 3.39E-50 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CIG75_RS11760 d75f71d40525cbed9200ee8518bbae74 747 Gene3D G3DSA:3.30.230.70 7 248 3.9E-60 T 28-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CIG75_RS11760 d75f71d40525cbed9200ee8518bbae74 747 Pfam PF03725 3' exoribonuclease family, domain 2 144 208 1.1E-14 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CIG75_RS11760 d75f71d40525cbed9200ee8518bbae74 747 Pfam PF03725 3' exoribonuclease family, domain 2 460 528 1.8E-7 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CIG75_RS11760 d75f71d40525cbed9200ee8518bbae74 747 Pfam PF00575 S1 RNA binding domain 620 691 7.9E-19 T 28-03-2018 IPR003029 S1 domain GO:0003676 CIG75_RS11760 d75f71d40525cbed9200ee8518bbae74 747 SMART SM00322 553 618 1.1E-11 T 28-03-2018 IPR004087 K Homology domain GO:0003676 CIG75_RS11760 d75f71d40525cbed9200ee8518bbae74 747 Pfam PF01138 3' exoribonuclease family, domain 1 324 457 3.3E-18 T 28-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CIG75_RS11760 d75f71d40525cbed9200ee8518bbae74 747 Pfam PF01138 3' exoribonuclease family, domain 1 12 141 4.3E-23 T 28-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CIG75_RS11760 d75f71d40525cbed9200ee8518bbae74 747 Gene3D G3DSA:2.40.50.140 627 697 1.2E-21 T 28-03-2018 CIG75_RS11760 d75f71d40525cbed9200ee8518bbae74 747 SUPERFAMILY SSF55666 454 561 3.27E-29 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CIG75_RS11760 d75f71d40525cbed9200ee8518bbae74 747 SUPERFAMILY SSF54791 555 641 2.16E-22 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CIG75_RS11760 d75f71d40525cbed9200ee8518bbae74 747 SUPERFAMILY SSF50249 621 696 3.28E-20 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CIG75_RS11760 d75f71d40525cbed9200ee8518bbae74 747 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 238 320 5.7E-17 T 28-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CIG75_RS11760 d75f71d40525cbed9200ee8518bbae74 747 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 9 692 0.0 T 28-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CIG75_RS11760 d75f71d40525cbed9200ee8518bbae74 747 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 1 694 31.151 T 28-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CIG75_RS11760 d75f71d40525cbed9200ee8518bbae74 747 PIRSF PIRSF005499 1 721 2.5E-301 T 28-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CIG75_RS11760 d75f71d40525cbed9200ee8518bbae74 747 SUPERFAMILY SSF54211 295 489 2.89E-49 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CIG75_RS11760 d75f71d40525cbed9200ee8518bbae74 747 SMART SM00316 621 691 2.1E-23 T 28-03-2018 IPR022967 RNA-binding domain, S1 CIG75_RS19885 6c876752adb72cf19e508220c703e5ac 358 Gene3D G3DSA:3.30.590.10 4 257 1.6E-76 T 28-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 CIG75_RS19885 6c876752adb72cf19e508220c703e5ac 358 ProSitePatterns PS00112 Phosphagen kinase active site signature. 169 175 - T 28-03-2018 IPR022415 ATP:guanido phosphotransferase active site GO:0016301|GO:0016772 Reactome: R-HSA-71288 CIG75_RS19885 6c876752adb72cf19e508220c703e5ac 358 Hamap MF_00602 Protein-arginine kinase [mcsB]. 12 352 35.469 T 28-03-2018 IPR023660 Protein arginine kinase GO:0006950|GO:0016775 CIG75_RS19885 6c876752adb72cf19e508220c703e5ac 358 Pfam PF00217 ATP:guanido phosphotransferase, C-terminal catalytic domain 65 255 8.0E-66 T 28-03-2018 IPR022414 ATP:guanido phosphotransferase, catalytic domain GO:0016301|GO:0016772 Reactome: R-HSA-71288 CIG75_RS19885 6c876752adb72cf19e508220c703e5ac 358 SUPERFAMILY SSF55931 10 270 1.57E-79 T 28-03-2018 CIG75_RS11010 d022c509fb4b80c1d7b3bb72d9f1a486 49 TIGRFAM TIGR03892 thiopep_precurs: thiazolylpeptide-type bacteriocin precursor 11 49 8.5E-10 T 28-03-2018 IPR023895 Thiazolylpeptide-type bacteriocin precursor CIG75_RS11020 d022c509fb4b80c1d7b3bb72d9f1a486 49 TIGRFAM TIGR03892 thiopep_precurs: thiazolylpeptide-type bacteriocin precursor 11 49 8.5E-10 T 28-03-2018 IPR023895 Thiazolylpeptide-type bacteriocin precursor CIG75_RS11015 d022c509fb4b80c1d7b3bb72d9f1a486 49 TIGRFAM TIGR03892 thiopep_precurs: thiazolylpeptide-type bacteriocin precursor 11 49 8.5E-10 T 28-03-2018 IPR023895 Thiazolylpeptide-type bacteriocin precursor CIG75_RS09430 1b5ada070ef522b79d33ef402091f942 90 Pfam PF00216 Bacterial DNA-binding protein 1 90 3.7E-35 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CIG75_RS09430 1b5ada070ef522b79d33ef402091f942 90 SUPERFAMILY SSF47729 1 90 6.33E-34 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CIG75_RS09430 1b5ada070ef522b79d33ef402091f942 90 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 4.6E-21 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CIG75_RS09430 1b5ada070ef522b79d33ef402091f942 90 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 4.6E-21 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CIG75_RS09430 1b5ada070ef522b79d33ef402091f942 90 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 4.6E-21 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CIG75_RS09430 1b5ada070ef522b79d33ef402091f942 90 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 28-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 CIG75_RS09430 1b5ada070ef522b79d33ef402091f942 90 Gene3D G3DSA:4.10.520.10 1 90 1.5E-36 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CIG75_RS09430 1b5ada070ef522b79d33ef402091f942 90 SMART SM00411 1 90 7.2E-48 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CIG75_RS00670 f6dd2c6f98af99dcc884d9872876fc4a 620 Pfam PF00664 ABC transporter transmembrane region 61 331 2.3E-54 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CIG75_RS00670 f6dd2c6f98af99dcc884d9872876fc4a 620 SMART SM00382 403 589 2.9E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS00670 f6dd2c6f98af99dcc884d9872876fc4a 620 ProSitePatterns PS00211 ABC transporters family signature. 515 529 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS00670 f6dd2c6f98af99dcc884d9872876fc4a 620 Gene3D G3DSA:3.40.50.300 367 619 3.0E-77 T 28-03-2018 CIG75_RS00670 f6dd2c6f98af99dcc884d9872876fc4a 620 Pfam PF00005 ABC transporter 394 543 2.0E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS00670 f6dd2c6f98af99dcc884d9872876fc4a 620 SUPERFAMILY SSF52540 370 613 8.84E-92 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS00670 f6dd2c6f98af99dcc884d9872876fc4a 620 SUPERFAMILY SSF90123 44 367 7.06E-92 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CIG75_RS00670 f6dd2c6f98af99dcc884d9872876fc4a 620 Gene3D G3DSA:1.20.1560.10 27 364 5.8E-91 T 28-03-2018 CIG75_RS19520 638420758337481d2e1fa8acf4d5f469 65 Pfam PF00313 'Cold-shock' DNA-binding domain 1 64 1.5E-29 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CIG75_RS19520 638420758337481d2e1fa8acf4d5f469 65 Gene3D G3DSA:2.40.50.140 1 65 4.8E-27 T 28-03-2018 CIG75_RS19520 638420758337481d2e1fa8acf4d5f469 65 PIRSF PIRSF002599 1 65 2.3E-23 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 CIG75_RS19520 638420758337481d2e1fa8acf4d5f469 65 ProSitePatterns PS00352 'Cold-shock' domain signature. 14 32 - T 28-03-2018 IPR019844 Cold-shock conserved site CIG75_RS19520 638420758337481d2e1fa8acf4d5f469 65 PRINTS PR00050 Cold shock protein signature 3 18 9.4E-20 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CIG75_RS19520 638420758337481d2e1fa8acf4d5f469 65 PRINTS PR00050 Cold shock protein signature 38 56 9.4E-20 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CIG75_RS19520 638420758337481d2e1fa8acf4d5f469 65 PRINTS PR00050 Cold shock protein signature 23 32 9.4E-20 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CIG75_RS19520 638420758337481d2e1fa8acf4d5f469 65 SMART SM00357 2 65 1.6E-29 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 CIG75_RS19520 638420758337481d2e1fa8acf4d5f469 65 SUPERFAMILY SSF50249 1 64 3.06E-24 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CIG75_RS16560 79e34b674d57787e0c9fde847ff58eea 191 Gene3D G3DSA:1.10.10.10 78 173 4.7E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS16560 79e34b674d57787e0c9fde847ff58eea 191 Pfam PF08281 Sigma-70, region 4 114 166 2.0E-13 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS16560 79e34b674d57787e0c9fde847ff58eea 191 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 39 70 - T 28-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS16560 79e34b674d57787e0c9fde847ff58eea 191 SUPERFAMILY SSF88659 98 172 1.72E-12 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS16560 79e34b674d57787e0c9fde847ff58eea 191 Pfam PF04542 Sigma-70 region 2 17 83 6.2E-14 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS16560 79e34b674d57787e0c9fde847ff58eea 191 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 13 170 4.8E-27 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS16560 79e34b674d57787e0c9fde847ff58eea 191 SUPERFAMILY SSF88946 12 97 3.02E-19 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS16560 79e34b674d57787e0c9fde847ff58eea 191 Gene3D G3DSA:1.10.1740.10 8 77 4.4E-18 T 28-03-2018 CIG75_RS18715 a5a5913e2b0c2cb8c80caff29a8f5e23 511 Gene3D G3DSA:3.40.50.620 213 386 3.8E-36 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CIG75_RS18715 a5a5913e2b0c2cb8c80caff29a8f5e23 511 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 7 193 5.2E-74 T 28-03-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CIG75_RS18715 a5a5913e2b0c2cb8c80caff29a8f5e23 511 SUPERFAMILY SSF52402 186 404 1.52E-57 T 28-03-2018 CIG75_RS18715 a5a5913e2b0c2cb8c80caff29a8f5e23 511 Pfam PF00117 Glutamine amidotransferase class-I 8 189 7.8E-38 T 28-03-2018 IPR017926 Glutamine amidotransferase CIG75_RS18715 a5a5913e2b0c2cb8c80caff29a8f5e23 511 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 202 511 1.0E-153 T 28-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CIG75_RS18715 a5a5913e2b0c2cb8c80caff29a8f5e23 511 SUPERFAMILY SSF54810 391 511 3.92E-50 T 28-03-2018 CIG75_RS18715 a5a5913e2b0c2cb8c80caff29a8f5e23 511 Pfam PF02540 NAD synthase 210 281 4.5E-6 T 28-03-2018 IPR022310 NAD/GMP synthase CIG75_RS18715 a5a5913e2b0c2cb8c80caff29a8f5e23 511 Gene3D G3DSA:3.40.50.880 2 212 3.2E-45 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CIG75_RS18715 a5a5913e2b0c2cb8c80caff29a8f5e23 511 SUPERFAMILY SSF52317 5 226 3.64E-53 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CIG75_RS18715 a5a5913e2b0c2cb8c80caff29a8f5e23 511 Pfam PF00958 GMP synthase C terminal domain 419 510 3.2E-44 T 28-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CIG75_RS18715 a5a5913e2b0c2cb8c80caff29a8f5e23 511 Gene3D G3DSA:3.30.300.10 387 511 3.2E-53 T 28-03-2018 CIG75_RS18715 a5a5913e2b0c2cb8c80caff29a8f5e23 511 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 4 511 54.138 T 28-03-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 CIG75_RS10210 deed3adb1f07caecbc11d769b07a1fe4 395 Hamap MF_01270 Anhydro-N-acetylmuramic acid kinase [anmK]. 7 390 37.383 T 28-03-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 KEGG: 00040+2.7.1.17 CIG75_RS10210 deed3adb1f07caecbc11d769b07a1fe4 395 SUPERFAMILY SSF53067 10 30 3.67E-16 T 28-03-2018 CIG75_RS10210 deed3adb1f07caecbc11d769b07a1fe4 395 SUPERFAMILY SSF53067 156 337 3.67E-16 T 28-03-2018 CIG75_RS10210 deed3adb1f07caecbc11d769b07a1fe4 395 SUPERFAMILY SSF53067 73 118 3.67E-16 T 28-03-2018 CIG75_RS10210 deed3adb1f07caecbc11d769b07a1fe4 395 Gene3D G3DSA:3.30.420.40 263 395 1.8E-21 T 28-03-2018 CIG75_RS10210 deed3adb1f07caecbc11d769b07a1fe4 395 Gene3D G3DSA:3.30.420.40 7 198 1.4E-52 T 28-03-2018 CIG75_RS10210 deed3adb1f07caecbc11d769b07a1fe4 395 Pfam PF03702 Anhydro-N-acetylmuramic acid kinase 9 387 5.4E-109 T 28-03-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 KEGG: 00040+2.7.1.17 CIG75_RS18075 a15374a5d56558bec4933109c945698a 325 Gene3D G3DSA:3.40.50.970 1 194 7.4E-62 T 28-03-2018 CIG75_RS18075 a15374a5d56558bec4933109c945698a 325 SMART SM00861 4 179 8.3E-60 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CIG75_RS18075 a15374a5d56558bec4933109c945698a 325 SUPERFAMILY SSF52518 4 193 3.64E-67 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CIG75_RS18075 a15374a5d56558bec4933109c945698a 325 SUPERFAMILY SSF52922 189 325 2.49E-38 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CIG75_RS18075 a15374a5d56558bec4933109c945698a 325 Pfam PF02780 Transketolase, C-terminal domain 194 313 1.1E-35 T 28-03-2018 IPR033248 Transketolase, C-terminal domain CIG75_RS18075 a15374a5d56558bec4933109c945698a 325 Pfam PF02779 Transketolase, pyrimidine binding domain 6 178 2.8E-44 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CIG75_RS18075 a15374a5d56558bec4933109c945698a 325 Gene3D G3DSA:3.40.50.920 195 324 1.3E-32 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CIG75_RS20250 c28ac80597b4a76d9dc7b55679851887 180 SUPERFAMILY SSF89447 1 51 1.12E-14 T 28-03-2018 CIG75_RS20250 c28ac80597b4a76d9dc7b55679851887 180 TIGRFAM TIGR02851 spore_V_T: stage V sporulation protein T 2 179 6.7E-85 T 28-03-2018 IPR014213 Sporulation stage V, protein T CIG75_RS20250 c28ac80597b4a76d9dc7b55679851887 180 Gene3D G3DSA:2.10.260.10 1 49 2.5E-20 T 28-03-2018 CIG75_RS20250 c28ac80597b4a76d9dc7b55679851887 180 Pfam PF15714 Stage V sporulation protein T C-terminal, transcription factor 54 179 3.8E-47 T 28-03-2018 CIG75_RS20250 c28ac80597b4a76d9dc7b55679851887 180 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 9 51 1.3E-10 T 28-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CIG75_RS20250 c28ac80597b4a76d9dc7b55679851887 180 PIRSF PIRSF026579 1 180 1.4E-88 T 28-03-2018 IPR014213 Sporulation stage V, protein T CIG75_RS20250 c28ac80597b4a76d9dc7b55679851887 180 SMART SM00966 8 52 1.1E-10 T 28-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CIG75_RS20250 c28ac80597b4a76d9dc7b55679851887 180 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 8 49 1.2E-15 T 28-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CIG75_RS17300 c52113a41abe1821a297ee64254346fa 1698 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 135 147 - T 28-03-2018 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 CIG75_RS17300 c52113a41abe1821a297ee64254346fa 1698 Gene3D G3DSA:3.30.450.40 1321 1496 6.9E-24 T 28-03-2018 IPR029016 GAF domain-like CIG75_RS17300 c52113a41abe1821a297ee64254346fa 1698 Pfam PF01590 GAF domain 1338 1460 1.4E-11 T 28-03-2018 IPR003018 GAF domain GO:0005515 CIG75_RS17300 c52113a41abe1821a297ee64254346fa 1698 SUPERFAMILY SSF55781 1324 1472 6.11E-21 T 28-03-2018 IPR029016 GAF domain-like CIG75_RS17300 c52113a41abe1821a297ee64254346fa 1698 SMART SM00065 1335 1470 2.2E-12 T 28-03-2018 IPR003018 GAF domain GO:0005515 CIG75_RS17300 c52113a41abe1821a297ee64254346fa 1698 SUPERFAMILY SSF55874 1577 1696 9.3E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS17300 c52113a41abe1821a297ee64254346fa 1698 Gene3D G3DSA:1.10.510.10 12 282 1.3E-39 T 28-03-2018 CIG75_RS17300 c52113a41abe1821a297ee64254346fa 1698 SMART SM00382 328 519 0.0033 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS17300 c52113a41abe1821a297ee64254346fa 1698 Pfam PF07730 Histidine kinase 1506 1569 3.6E-14 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CIG75_RS17300 c52113a41abe1821a297ee64254346fa 1698 SMART SM00219 31 274 1.6E-4 T 28-03-2018 IPR020635 Tyrosine-protein kinase, catalytic domain GO:0004713|GO:0006468 CIG75_RS17300 c52113a41abe1821a297ee64254346fa 1698 SUPERFAMILY SSF52540 306 578 8.2E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS17300 c52113a41abe1821a297ee64254346fa 1698 Gene3D G3DSA:3.30.565.10 1569 1698 9.7E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS17300 c52113a41abe1821a297ee64254346fa 1698 SUPERFAMILY SSF48452 1202 1293 5.44E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS17300 c52113a41abe1821a297ee64254346fa 1698 Pfam PF13191 AAA ATPase domain 307 494 3.0E-38 T 28-03-2018 CIG75_RS17300 c52113a41abe1821a297ee64254346fa 1698 SUPERFAMILY SSF56112 16 273 1.22E-44 T 28-03-2018 IPR011009 Protein kinase-like domain CIG75_RS17300 c52113a41abe1821a297ee64254346fa 1698 Gene3D G3DSA:1.25.40.10 745 1320 5.1E-21 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS17300 c52113a41abe1821a297ee64254346fa 1698 Pfam PF00069 Protein kinase domain 32 265 2.1E-26 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CIG75_RS17300 c52113a41abe1821a297ee64254346fa 1698 Gene3D G3DSA:3.40.50.300 296 498 1.2E-14 T 28-03-2018 CIG75_RS18610 043f4fa264089e4f4ab38f3382212b27 237 TIGRFAM TIGR03717 R_switched_YjbE: integral membrane protein, YjbE family 10 183 7.8E-57 T 28-03-2018 IPR022301 Integral membrane protein YjbE CIG75_RS18610 043f4fa264089e4f4ab38f3382212b27 237 Pfam PF03741 Integral membrane protein TerC family 12 181 2.6E-41 T 28-03-2018 IPR005496 Integral membrane protein TerC GO:0016021 CIG75_RS13015 7fd2dfb2486f72662fa823c969182951 310 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 43 62 - T 28-03-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 CIG75_RS13015 7fd2dfb2486f72662fa823c969182951 310 SUPERFAMILY SSF51395 3 305 1.28E-91 T 28-03-2018 CIG75_RS13015 7fd2dfb2486f72662fa823c969182951 310 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 7 305 7.3E-118 T 28-03-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 CIG75_RS13015 7fd2dfb2486f72662fa823c969182951 310 PIRSF PIRSF000164 1 306 6.6E-84 T 28-03-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 CIG75_RS13015 7fd2dfb2486f72662fa823c969182951 310 Hamap MF_00224 Dihydroorotate dehydrogenase [pyrD]. 7 304 41.543 T 28-03-2018 IPR024920 Dihydroorotate dehydrogenase, class 1 GO:0004152|GO:0005737|GO:0006221 CIG75_RS13015 7fd2dfb2486f72662fa823c969182951 310 Pfam PF01180 Dihydroorotate dehydrogenase 7 286 3.8E-86 T 28-03-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 CIG75_RS13015 7fd2dfb2486f72662fa823c969182951 310 Gene3D G3DSA:3.20.20.70 1 309 3.9E-71 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CIG75_RS13015 7fd2dfb2486f72662fa823c969182951 310 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 242 262 - T 28-03-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 CIG75_RS06960 4b337ea34a463330d8a3cbfbd29a5e0c 83 Pfam PF06135 Bacterial protein of unknown function (DUF965) 4 79 2.8E-30 T 28-03-2018 IPR009309 Uncharacterised protein family UPF0297 CIG75_RS01355 ab2bbb7a62d5bb464772649f06e491a4 599 SUPERFAMILY SSF90123 5 320 1.57E-73 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CIG75_RS01355 ab2bbb7a62d5bb464772649f06e491a4 599 Pfam PF00664 ABC transporter transmembrane region 21 291 1.5E-41 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CIG75_RS01355 ab2bbb7a62d5bb464772649f06e491a4 599 Gene3D G3DSA:1.20.1560.10 1 323 7.3E-60 T 28-03-2018 CIG75_RS01355 ab2bbb7a62d5bb464772649f06e491a4 599 SMART SM00382 362 554 1.5E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS01355 ab2bbb7a62d5bb464772649f06e491a4 599 Pfam PF00005 ABC transporter 353 500 3.2E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS01355 ab2bbb7a62d5bb464772649f06e491a4 599 ProSitePatterns PS00211 ABC transporters family signature. 474 488 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS01355 ab2bbb7a62d5bb464772649f06e491a4 599 SUPERFAMILY SSF52540 331 573 9.08E-85 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS01355 ab2bbb7a62d5bb464772649f06e491a4 599 Gene3D G3DSA:3.40.50.300 324 578 5.3E-70 T 28-03-2018 CIG75_RS14255 ef7b65d887356ba2e1734b9abe7039ac 227 PRINTS PR01837 MgtC/SapB protein signature 65 87 1.4E-41 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CIG75_RS14255 ef7b65d887356ba2e1734b9abe7039ac 227 PRINTS PR01837 MgtC/SapB protein signature 12 31 1.4E-41 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CIG75_RS14255 ef7b65d887356ba2e1734b9abe7039ac 227 PRINTS PR01837 MgtC/SapB protein signature 31 49 1.4E-41 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CIG75_RS14255 ef7b65d887356ba2e1734b9abe7039ac 227 PRINTS PR01837 MgtC/SapB protein signature 93 117 1.4E-41 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CIG75_RS14255 ef7b65d887356ba2e1734b9abe7039ac 227 Pfam PF02308 MgtC family 9 136 5.5E-33 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CIG75_RS09650 81d160c2c13f9210e708db00664a84d5 278 SUPERFAMILY SSF53850 7 267 7.19E-67 T 28-03-2018 CIG75_RS09650 81d160c2c13f9210e708db00664a84d5 278 Gene3D G3DSA:3.40.190.10 133 261 9.1E-22 T 28-03-2018 CIG75_RS09650 81d160c2c13f9210e708db00664a84d5 278 Gene3D G3DSA:3.40.190.10 1 127 1.3E-15 T 28-03-2018 CIG75_RS09650 81d160c2c13f9210e708db00664a84d5 278 Pfam PF02621 Menaquinone biosynthesis 8 260 4.1E-58 T 28-03-2018 IPR003773 Menaquinone biosynthesis enzyme CIG75_RS09650 81d160c2c13f9210e708db00664a84d5 278 Hamap MF_00995 Chorismate dehydratase [mqnA]. 8 265 25.011 T 28-03-2018 IPR030868 Chorismate dehydratase GO:0009234|GO:0016829 KEGG: 00130+4.2.1.151|MetaCyc: PWY-7371|MetaCyc: PWY-7374 CIG75_RS10430 984ed27ab60a191f127ab182efb076ca 555 Gene3D G3DSA:3.40.1770.10 7 150 1.2E-28 T 28-03-2018 CIG75_RS10430 984ed27ab60a191f127ab182efb076ca 555 Gene3D G3DSA:3.40.1770.10 193 551 1.8E-164 T 28-03-2018 CIG75_RS10430 984ed27ab60a191f127ab182efb076ca 555 Pfam PF17391 Urocanase N-terminal domain 9 135 1.3E-61 T 28-03-2018 IPR035400 Urocanase, N-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CIG75_RS10430 984ed27ab60a191f127ab182efb076ca 555 Hamap MF_00577 Urocanate hydratase [hutU]. 2 553 51.826 T 28-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CIG75_RS10430 984ed27ab60a191f127ab182efb076ca 555 Pfam PF17392 Urocanase C-terminal domain 349 543 5.6E-96 T 28-03-2018 IPR035401 Urocanase, C-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CIG75_RS10430 984ed27ab60a191f127ab182efb076ca 555 SUPERFAMILY SSF111326 4 552 1.27E-261 T 28-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CIG75_RS10430 984ed27ab60a191f127ab182efb076ca 555 Pfam PF01175 Urocanase Rossmann-like domain 138 346 2.6E-89 T 28-03-2018 IPR035085 Urocanase, Rossmann-like domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CIG75_RS10430 984ed27ab60a191f127ab182efb076ca 555 TIGRFAM TIGR01228 hutU: urocanate hydratase 7 551 1.6E-303 T 28-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CIG75_RS10430 984ed27ab60a191f127ab182efb076ca 555 ProSitePatterns PS01233 Urocanase signature. 439 454 - T 28-03-2018 IPR023636 Urocanase conserved site GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CIG75_RS10430 984ed27ab60a191f127ab182efb076ca 555 PIRSF PIRSF001423 1 555 1.2E-296 T 28-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CIG75_RS01335 de3ebf985922896210fc11558013d7bd 368 Gene3D G3DSA:1.20.1250.20 1 176 1.0E-33 T 28-03-2018 CIG75_RS01335 de3ebf985922896210fc11558013d7bd 368 Pfam PF07690 Major Facilitator Superfamily 1 214 2.9E-33 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CIG75_RS01335 de3ebf985922896210fc11558013d7bd 368 Gene3D G3DSA:1.20.1250.20 180 368 1.8E-27 T 28-03-2018 CIG75_RS01335 de3ebf985922896210fc11558013d7bd 368 SUPERFAMILY SSF103473 1 365 1.96E-65 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS17260 420f50cce57670ec33017be1c7668911 286 Pfam PF00583 Acetyltransferase (GNAT) family 52 126 4.6E-9 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CIG75_RS17260 420f50cce57670ec33017be1c7668911 286 Pfam PF00583 Acetyltransferase (GNAT) family 187 273 1.1E-10 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CIG75_RS17260 420f50cce57670ec33017be1c7668911 286 SUPERFAMILY SSF55729 15 128 2.19E-15 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CIG75_RS17260 420f50cce57670ec33017be1c7668911 286 Gene3D G3DSA:3.40.630.30 144 285 3.0E-20 T 28-03-2018 CIG75_RS17260 420f50cce57670ec33017be1c7668911 286 SUPERFAMILY SSF55729 134 282 2.03E-21 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CIG75_RS17260 420f50cce57670ec33017be1c7668911 286 Gene3D G3DSA:3.40.630.30 4 143 3.3E-15 T 28-03-2018 CIG75_RS16910 94b4d41313f73de8d1941ad34c2d606c 363 SUPERFAMILY SSF159672 4 248 3.27E-59 T 28-03-2018 CIG75_RS16910 94b4d41313f73de8d1941ad34c2d606c 363 SUPERFAMILY SSF159664 234 360 3.14E-40 T 28-03-2018 IPR002750 CobE/GbiG C-terminal domain GO:0009236 CIG75_RS16910 94b4d41313f73de8d1941ad34c2d606c 363 Pfam PF11761 Cobalamin biosynthesis central region 142 238 2.6E-14 T 28-03-2018 IPR021745 Cobalamin biosynthesis central region KEGG: 00860+3.7.1.12|MetaCyc: PWY-7377 CIG75_RS16910 94b4d41313f73de8d1941ad34c2d606c 363 Pfam PF11760 Cobalamin synthesis G N-terminal 57 136 4.4E-34 T 28-03-2018 IPR021744 Cobalamin synthesis G, N-terminal KEGG: 00860+3.7.1.12|MetaCyc: PWY-7377 CIG75_RS16910 94b4d41313f73de8d1941ad34c2d606c 363 Pfam PF01890 Cobalamin synthesis G C-terminus 241 358 8.6E-38 T 28-03-2018 IPR002750 CobE/GbiG C-terminal domain GO:0009236 CIG75_RS16910 94b4d41313f73de8d1941ad34c2d606c 363 Gene3D G3DSA:3.30.420.180 231 361 3.5E-42 T 28-03-2018 IPR002750 CobE/GbiG C-terminal domain GO:0009236 CIG75_RS07115 544dca41489ec3b5c6d2349685886792 813 SMART SM00849 560 761 0.0069 T 28-03-2018 IPR001279 Metallo-beta-lactamase CIG75_RS07115 544dca41489ec3b5c6d2349685886792 813 Pfam PF00753 Metallo-beta-lactamase superfamily 558 747 7.2E-6 T 28-03-2018 IPR001279 Metallo-beta-lactamase CIG75_RS07115 544dca41489ec3b5c6d2349685886792 813 SUPERFAMILY SSF56281 548 806 2.17E-40 T 28-03-2018 IPR001279 Metallo-beta-lactamase CIG75_RS07115 544dca41489ec3b5c6d2349685886792 813 Gene3D G3DSA:3.60.15.10 551 800 3.1E-23 T 28-03-2018 IPR001279 Metallo-beta-lactamase CIG75_RS07115 544dca41489ec3b5c6d2349685886792 813 Pfam PF03772 Competence protein 263 522 2.8E-49 T 28-03-2018 IPR004477 ComEC/Rec2-related protein CIG75_RS07115 544dca41489ec3b5c6d2349685886792 813 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 284 455 6.0E-29 T 28-03-2018 IPR004477 ComEC/Rec2-related protein CIG75_RS07115 544dca41489ec3b5c6d2349685886792 813 TIGRFAM TIGR00361 ComEC_Rec2: DNA internalization-related competence protein ComEC/Rec2 165 790 6.3E-68 T 28-03-2018 IPR004797 Competence protein ComEC/Rec2 GO:0016021|GO:0030420 CIG75_RS07115 544dca41489ec3b5c6d2349685886792 813 Pfam PF13567 Domain of unknown function (DUF4131) 76 224 6.9E-22 T 28-03-2018 IPR025405 Domain of unknown function DUF4131 CIG75_RS10100 491f439643354c7a1458f866922463ac 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 2.2E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS10100 491f439643354c7a1458f866922463ac 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 2.2E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS10100 491f439643354c7a1458f866922463ac 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 2.2E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS10100 491f439643354c7a1458f866922463ac 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 2.2E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS10100 491f439643354c7a1458f866922463ac 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 2.2E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS10100 491f439643354c7a1458f866922463ac 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 2.2E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS10100 491f439643354c7a1458f866922463ac 246 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 218 5.1E-4 T 28-03-2018 CIG75_RS10100 491f439643354c7a1458f866922463ac 246 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 245 2.8E-75 T 28-03-2018 CIG75_RS10100 491f439643354c7a1458f866922463ac 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 3.0E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS10100 491f439643354c7a1458f866922463ac 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 3.0E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS10100 491f439643354c7a1458f866922463ac 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 3.0E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS10100 491f439643354c7a1458f866922463ac 246 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CIG75_RS10100 491f439643354c7a1458f866922463ac 246 Gene3D G3DSA:3.40.50.720 41 246 1.0E-72 T 28-03-2018 CIG75_RS10100 491f439643354c7a1458f866922463ac 246 Gene3D G3DSA:3.40.50.720 1 40 3.0E-9 T 28-03-2018 CIG75_RS10100 491f439643354c7a1458f866922463ac 246 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 8 244 1.2E-90 T 28-03-2018 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CIG75_RS10100 491f439643354c7a1458f866922463ac 246 SUPERFAMILY SSF51735 4 245 5.72E-92 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS16705 14bdc03b5924181f2312a706381b368c 327 Pfam PF02790 Cytochrome C oxidase subunit II, transmembrane domain 21 102 2.8E-17 T 28-03-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CIG75_RS16705 14bdc03b5924181f2312a706381b368c 327 SUPERFAMILY SSF81464 20 111 5.72E-19 T 28-03-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CIG75_RS16705 14bdc03b5924181f2312a706381b368c 327 Gene3D G3DSA:1.10.760.10 238 327 2.4E-12 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CIG75_RS16705 14bdc03b5924181f2312a706381b368c 327 SUPERFAMILY SSF46626 241 326 4.65E-13 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CIG75_RS16705 14bdc03b5924181f2312a706381b368c 327 Gene3D G3DSA:1.10.287.90 19 112 2.2E-21 T 28-03-2018 CIG75_RS16705 14bdc03b5924181f2312a706381b368c 327 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 140 213 1.2E-10 T 28-03-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CIG75_RS16705 14bdc03b5924181f2312a706381b368c 327 Gene3D G3DSA:2.60.40.420 113 232 2.4E-29 T 28-03-2018 IPR008972 Cupredoxin CIG75_RS16705 14bdc03b5924181f2312a706381b368c 327 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 158 212 - T 28-03-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CIG75_RS16705 14bdc03b5924181f2312a706381b368c 327 SUPERFAMILY SSF49503 109 269 1.54E-38 T 28-03-2018 IPR008972 Cupredoxin CIG75_RS16705 14bdc03b5924181f2312a706381b368c 327 TIGRFAM TIGR02866 CoxB: cytochrome c oxidase, subunit II 32 228 1.2E-52 T 28-03-2018 IPR014222 Cytochrome c oxidase, subunit II GO:0016021|GO:0016491 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CIG75_RS16705 14bdc03b5924181f2312a706381b368c 327 PRINTS PR01166 Cytochrome c oxidase subunit II signature 78 90 1.5E-12 T 28-03-2018 CIG75_RS16705 14bdc03b5924181f2312a706381b368c 327 PRINTS PR01166 Cytochrome c oxidase subunit II signature 112 131 1.5E-12 T 28-03-2018 CIG75_RS16705 14bdc03b5924181f2312a706381b368c 327 PRINTS PR01166 Cytochrome c oxidase subunit II signature 201 218 1.5E-12 T 28-03-2018 CIG75_RS16705 14bdc03b5924181f2312a706381b368c 327 PRINTS PR01166 Cytochrome c oxidase subunit II signature 90 110 1.5E-12 T 28-03-2018 CIG75_RS16705 14bdc03b5924181f2312a706381b368c 327 Pfam PF00034 Cytochrome c 243 326 1.3E-8 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CIG75_RS08375 ba505edee2f1e89de88e84919c0e4828 235 SUPERFAMILY SSF53448 17 199 7.68E-35 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CIG75_RS08375 ba505edee2f1e89de88e84919c0e4828 235 Pfam PF00535 Glycosyl transferase family 2 18 139 7.0E-25 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CIG75_RS08375 ba505edee2f1e89de88e84919c0e4828 235 Gene3D G3DSA:3.90.550.10 2 235 1.7E-32 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CIG75_RS00355 fd5f79b8e1b90489373ea752a8550805 87 Pfam PF13031 Protein of unknown function (DUF3892) 4 74 1.3E-4 T 28-03-2018 IPR024997 Protein of unknown function DUF3892 CIG75_RS18660 b1c70c0b7d44979daa731ec5fc35c714 344 Pfam PF02769 AIR synthase related protein, C-terminal domain 173 338 1.3E-36 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CIG75_RS18660 b1c70c0b7d44979daa731ec5fc35c714 344 Gene3D G3DSA:3.90.650.10 168 341 8.0E-61 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CIG75_RS18660 b1c70c0b7d44979daa731ec5fc35c714 344 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 5 334 1.6E-140 T 28-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CIG75_RS18660 b1c70c0b7d44979daa731ec5fc35c714 344 Pfam PF00586 AIR synthase related protein, N-terminal domain 60 161 2.3E-19 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CIG75_RS18660 b1c70c0b7d44979daa731ec5fc35c714 344 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 3 344 47.136 T 28-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CIG75_RS18660 b1c70c0b7d44979daa731ec5fc35c714 344 SUPERFAMILY SSF55326 3 167 5.68E-53 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CIG75_RS18660 b1c70c0b7d44979daa731ec5fc35c714 344 SUPERFAMILY SSF56042 170 338 2.24E-60 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CIG75_RS18660 b1c70c0b7d44979daa731ec5fc35c714 344 Gene3D G3DSA:3.30.1330.10 30 158 2.6E-57 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CIG75_RS13450 ab1fa76d45ad6857ef620a4f2617d9d2 358 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 9 337 39.184 T 28-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 CIG75_RS13450 ab1fa76d45ad6857ef620a4f2617d9d2 358 Gene3D G3DSA:3.30.1330.20 215 324 2.0E-45 T 28-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 CIG75_RS13450 ab1fa76d45ad6857ef620a4f2617d9d2 358 Gene3D G3DSA:3.40.50.1440 8 214 1.1E-46 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CIG75_RS13450 ab1fa76d45ad6857ef620a4f2617d9d2 358 ProSitePatterns PS01135 FtsZ protein signature 2. 97 118 - T 28-03-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 CIG75_RS13450 ab1fa76d45ad6857ef620a4f2617d9d2 358 Pfam PF12327 FtsZ family, C-terminal domain 222 316 4.5E-33 T 28-03-2018 IPR024757 Cell division protein FtsZ, C-terminal CIG75_RS13450 ab1fa76d45ad6857ef620a4f2617d9d2 358 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 13 173 6.7E-45 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CIG75_RS13450 ab1fa76d45ad6857ef620a4f2617d9d2 358 PRINTS PR00423 Cell division protein FtsZ signature 212 233 1.2E-52 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CIG75_RS13450 ab1fa76d45ad6857ef620a4f2617d9d2 358 PRINTS PR00423 Cell division protein FtsZ signature 126 147 1.2E-52 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CIG75_RS13450 ab1fa76d45ad6857ef620a4f2617d9d2 358 PRINTS PR00423 Cell division protein FtsZ signature 189 211 1.2E-52 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CIG75_RS13450 ab1fa76d45ad6857ef620a4f2617d9d2 358 PRINTS PR00423 Cell division protein FtsZ signature 98 118 1.2E-52 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CIG75_RS13450 ab1fa76d45ad6857ef620a4f2617d9d2 358 ProSitePatterns PS01134 FtsZ protein signature 1. 44 78 - T 28-03-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 CIG75_RS13450 ab1fa76d45ad6857ef620a4f2617d9d2 358 SUPERFAMILY SSF52490 12 208 1.06E-74 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CIG75_RS13450 ab1fa76d45ad6857ef620a4f2617d9d2 358 SMART SM00865 207 324 1.1E-54 T 28-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 CIG75_RS13450 ab1fa76d45ad6857ef620a4f2617d9d2 358 SUPERFAMILY SSF55307 204 318 5.49E-44 T 28-03-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 CIG75_RS13450 ab1fa76d45ad6857ef620a4f2617d9d2 358 SMART SM00864 13 205 1.0E-122 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CIG75_RS13450 ab1fa76d45ad6857ef620a4f2617d9d2 358 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 10 330 4.3E-139 T 28-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 CIG75_RS15620 bf190cf18036bf78cd5e43dc443bd440 292 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 253 271 5.5E-50 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CIG75_RS15620 bf190cf18036bf78cd5e43dc443bd440 292 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 202 231 5.5E-50 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CIG75_RS15620 bf190cf18036bf78cd5e43dc443bd440 292 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 32 54 5.5E-50 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CIG75_RS15620 bf190cf18036bf78cd5e43dc443bd440 292 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 153 173 5.5E-50 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CIG75_RS15620 bf190cf18036bf78cd5e43dc443bd440 292 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 73 100 5.5E-50 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CIG75_RS15620 bf190cf18036bf78cd5e43dc443bd440 292 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 108 129 5.5E-50 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CIG75_RS15620 bf190cf18036bf78cd5e43dc443bd440 292 SUPERFAMILY SSF51735 133 276 3.33E-35 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS15620 bf190cf18036bf78cd5e43dc443bd440 292 Hamap MF_01576 Bifunctional protein FolD [folD]. 2 280 31.536 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CIG75_RS15620 bf190cf18036bf78cd5e43dc443bd440 292 SUPERFAMILY SSF53223 1 120 2.3E-34 T 28-03-2018 CIG75_RS15620 bf190cf18036bf78cd5e43dc443bd440 292 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 123 277 2.1E-48 T 28-03-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CIG75_RS15620 bf190cf18036bf78cd5e43dc443bd440 292 Gene3D G3DSA:3.40.50.10860 10 138 3.2E-39 T 28-03-2018 CIG75_RS15620 bf190cf18036bf78cd5e43dc443bd440 292 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 6 119 6.1E-35 T 28-03-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CIG75_RS15620 bf190cf18036bf78cd5e43dc443bd440 292 Gene3D G3DSA:3.40.50.720 139 261 5.3E-31 T 28-03-2018 CIG75_RS03850 d35f781389e8912d41a25c9f0ed0391b 461 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 279 458 1.9E-21 T 28-03-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 CIG75_RS03850 d35f781389e8912d41a25c9f0ed0391b 461 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 23 451 2.9E-170 T 28-03-2018 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 CIG75_RS03850 d35f781389e8912d41a25c9f0ed0391b 461 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 389 420 - T 28-03-2018 IPR030390 RNA methyltransferase TrmA, active site CIG75_RS03850 d35f781389e8912d41a25c9f0ed0391b 461 Gene3D G3DSA:2.40.50.140 2 81 2.2E-26 T 28-03-2018 CIG75_RS03850 d35f781389e8912d41a25c9f0ed0391b 461 Pfam PF01938 TRAM domain 11 65 3.7E-12 T 28-03-2018 IPR002792 TRAM domain CIG75_RS03850 d35f781389e8912d41a25c9f0ed0391b 461 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 441 451 - T 28-03-2018 IPR030391 RNA methyltransferase TrmA, conserved site CIG75_RS03850 d35f781389e8912d41a25c9f0ed0391b 461 SUPERFAMILY SSF53335 75 458 1.01E-89 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CIG75_RS03850 d35f781389e8912d41a25c9f0ed0391b 461 SUPERFAMILY SSF50249 3 67 4.74E-18 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CIG75_RS03850 d35f781389e8912d41a25c9f0ed0391b 461 Gene3D G3DSA:3.40.50.150 82 145 7.7E-12 T 28-03-2018 CIG75_RS03850 d35f781389e8912d41a25c9f0ed0391b 461 Gene3D G3DSA:3.40.50.150 155 457 4.2E-51 T 28-03-2018 CIG75_RS10585 72ca4193ddc4aef893aaf6a45264065a 2136 SUPERFAMILY SSF52777 1094 1264 6.0E-52 T 28-03-2018 CIG75_RS10585 72ca4193ddc4aef893aaf6a45264065a 2136 Gene3D G3DSA:3.30.559.10 20 245 1.4E-41 T 28-03-2018 CIG75_RS10585 72ca4193ddc4aef893aaf6a45264065a 2136 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1029 1044 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS10585 72ca4193ddc4aef893aaf6a45264065a 2136 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 524 919 2.2E-130 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS10585 72ca4193ddc4aef893aaf6a45264065a 2136 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1569 1960 9.1E-122 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS10585 72ca4193ddc4aef893aaf6a45264065a 2136 Gene3D G3DSA:3.30.559.10 1077 1266 2.1E-45 T 28-03-2018 CIG75_RS10585 72ca4193ddc4aef893aaf6a45264065a 2136 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2068 2083 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS10585 72ca4193ddc4aef893aaf6a45264065a 2136 SUPERFAMILY SSF56801 1509 2056 3.01E-147 T 28-03-2018 CIG75_RS10585 72ca4193ddc4aef893aaf6a45264065a 2136 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1688 1699 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS10585 72ca4193ddc4aef893aaf6a45264065a 2136 Gene3D G3DSA:2.30.38.10 804 888 4.2E-25 T 28-03-2018 CIG75_RS10585 72ca4193ddc4aef893aaf6a45264065a 2136 Pfam PF00550 Phosphopantetheine attachment site 1006 1070 2.6E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10585 72ca4193ddc4aef893aaf6a45264065a 2136 Pfam PF00550 Phosphopantetheine attachment site 2045 2109 7.1E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10585 72ca4193ddc4aef893aaf6a45264065a 2136 SMART SM00823 Phosphopantetheine attachment site 1005 1074 4.9E-5 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS10585 72ca4193ddc4aef893aaf6a45264065a 2136 SMART SM00823 Phosphopantetheine attachment site 2044 2113 0.0056 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS10585 72ca4193ddc4aef893aaf6a45264065a 2136 ProSitePatterns PS00455 Putative AMP-binding domain signature. 645 656 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS10585 72ca4193ddc4aef893aaf6a45264065a 2136 Gene3D G3DSA:1.10.1200.10 1011 1076 5.7E-25 T 28-03-2018 CIG75_RS10585 72ca4193ddc4aef893aaf6a45264065a 2136 Pfam PF00501 AMP-binding enzyme 504 895 1.3E-94 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS10585 72ca4193ddc4aef893aaf6a45264065a 2136 Pfam PF00501 AMP-binding enzyme 1548 1936 3.2E-88 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS10585 72ca4193ddc4aef893aaf6a45264065a 2136 Gene3D G3DSA:3.40.50.980 651 803 4.6E-25 T 28-03-2018 CIG75_RS10585 72ca4193ddc4aef893aaf6a45264065a 2136 Gene3D G3DSA:3.40.50.980 1694 1845 5.3E-29 T 28-03-2018 CIG75_RS10585 72ca4193ddc4aef893aaf6a45264065a 2136 Gene3D G3DSA:2.30.38.10 1846 1926 6.3E-23 T 28-03-2018 CIG75_RS10585 72ca4193ddc4aef893aaf6a45264065a 2136 Pfam PF00668 Condensation domain 38 479 5.7E-116 T 28-03-2018 IPR001242 Condensation domain CIG75_RS10585 72ca4193ddc4aef893aaf6a45264065a 2136 Pfam PF00668 Condensation domain 1092 1526 3.6E-115 T 28-03-2018 IPR001242 Condensation domain CIG75_RS10585 72ca4193ddc4aef893aaf6a45264065a 2136 Gene3D G3DSA:1.10.1200.10 2050 2126 6.0E-23 T 28-03-2018 CIG75_RS10585 72ca4193ddc4aef893aaf6a45264065a 2136 SUPERFAMILY SSF52777 226 491 2.78E-69 T 28-03-2018 CIG75_RS10585 72ca4193ddc4aef893aaf6a45264065a 2136 SUPERFAMILY SSF47336 997 1070 7.46E-22 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10585 72ca4193ddc4aef893aaf6a45264065a 2136 Gene3D G3DSA:3.40.50.980 495 650 4.9E-48 T 28-03-2018 CIG75_RS10585 72ca4193ddc4aef893aaf6a45264065a 2136 Gene3D G3DSA:3.40.50.980 1539 1693 3.1E-40 T 28-03-2018 CIG75_RS10585 72ca4193ddc4aef893aaf6a45264065a 2136 SUPERFAMILY SSF47336 2036 2109 1.57E-18 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10585 72ca4193ddc4aef893aaf6a45264065a 2136 SUPERFAMILY SSF56801 462 1017 1.7E-154 T 28-03-2018 CIG75_RS10585 72ca4193ddc4aef893aaf6a45264065a 2136 Gene3D G3DSA:3.30.300.30 1931 2049 3.7E-39 T 28-03-2018 CIG75_RS10585 72ca4193ddc4aef893aaf6a45264065a 2136 Gene3D G3DSA:3.30.300.30 890 1010 5.1E-44 T 28-03-2018 CIG75_RS10585 72ca4193ddc4aef893aaf6a45264065a 2136 Pfam PF13193 AMP-binding enzyme C-terminal domain 903 978 8.3E-15 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS10585 72ca4193ddc4aef893aaf6a45264065a 2136 Pfam PF13193 AMP-binding enzyme C-terminal domain 1944 2018 3.9E-13 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS10585 72ca4193ddc4aef893aaf6a45264065a 2136 SUPERFAMILY SSF52777 42 218 2.22E-49 T 28-03-2018 CIG75_RS10585 72ca4193ddc4aef893aaf6a45264065a 2136 SUPERFAMILY SSF52777 1272 1534 4.34E-62 T 28-03-2018 CIG75_RS11570 65587cef32af222ceb7ca07f5ca92a43 513 SUPERFAMILY SSF109604 309 460 8.3E-33 T 28-03-2018 CIG75_RS11570 65587cef32af222ceb7ca07f5ca92a43 513 Gene3D G3DSA:1.10.3210.10 236 468 5.8E-36 T 28-03-2018 CIG75_RS11570 65587cef32af222ceb7ca07f5ca92a43 513 Pfam PF01966 HD domain 330 421 4.3E-18 T 28-03-2018 IPR006674 HD domain CIG75_RS11570 65587cef32af222ceb7ca07f5ca92a43 513 Hamap MF_00335 Ribonuclease Y [rny]. 5 513 25.853 T 28-03-2018 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 CIG75_RS11570 65587cef32af222ceb7ca07f5ca92a43 513 TIGRFAM TIGR03319 RNase_Y: ribonuclease Y 8 513 7.9E-242 T 28-03-2018 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 CIG75_RS11570 65587cef32af222ceb7ca07f5ca92a43 513 SMART SM00322 201 268 2.3E-7 T 28-03-2018 IPR004087 K Homology domain GO:0003676 CIG75_RS11570 65587cef32af222ceb7ca07f5ca92a43 513 SMART SM00471 325 431 6.4E-13 T 28-03-2018 IPR003607 HD/PDEase domain CIG75_RS11570 65587cef32af222ceb7ca07f5ca92a43 513 Gene3D G3DSA:3.30.300.20 146 235 6.1E-12 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CIG75_RS11570 65587cef32af222ceb7ca07f5ca92a43 513 SUPERFAMILY SSF54791 201 297 3.04E-17 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CIG75_RS11570 65587cef32af222ceb7ca07f5ca92a43 513 Pfam PF00013 KH domain 207 263 2.7E-6 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CIG75_RS11570 65587cef32af222ceb7ca07f5ca92a43 513 TIGRFAM TIGR00277 HDIG: HDIG domain 325 402 1.1E-24 T 28-03-2018 IPR006675 HDIG domain CIG75_RS11570 65587cef32af222ceb7ca07f5ca92a43 513 Pfam PF12072 Domain of unknown function (DUF3552) 6 198 2.2E-68 T 28-03-2018 IPR022711 Ribonuclease Y, N-terminal CIG75_RS00745 1f4d0204bced96dc2204f3639dd4ca84 244 Gene3D G3DSA:3.40.50.720 1 50 9.2E-10 T 28-03-2018 CIG75_RS00745 1f4d0204bced96dc2204f3639dd4ca84 244 Gene3D G3DSA:3.40.50.720 51 244 3.5E-62 T 28-03-2018 CIG75_RS00745 1f4d0204bced96dc2204f3639dd4ca84 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 168 5.7E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS00745 1f4d0204bced96dc2204f3639dd4ca84 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 5.7E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS00745 1f4d0204bced96dc2204f3639dd4ca84 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 5.7E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS00745 1f4d0204bced96dc2204f3639dd4ca84 244 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 242 2.3E-71 T 28-03-2018 CIG75_RS00745 1f4d0204bced96dc2204f3639dd4ca84 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 6.8E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS00745 1f4d0204bced96dc2204f3639dd4ca84 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 6.8E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS00745 1f4d0204bced96dc2204f3639dd4ca84 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 205 225 6.8E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS00745 1f4d0204bced96dc2204f3639dd4ca84 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 6.8E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS00745 1f4d0204bced96dc2204f3639dd4ca84 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 6.8E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS00745 1f4d0204bced96dc2204f3639dd4ca84 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 6.8E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS00745 1f4d0204bced96dc2204f3639dd4ca84 244 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 136 164 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CIG75_RS00745 1f4d0204bced96dc2204f3639dd4ca84 244 SUPERFAMILY SSF51735 5 243 4.03E-82 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS06005 fdb0daf179a5e7f3c62d34ad5b626d50 267 SUPERFAMILY SSF75217 112 265 1.37E-43 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CIG75_RS06005 fdb0daf179a5e7f3c62d34ad5b626d50 267 Pfam PF00588 SpoU rRNA Methylase family 120 259 4.8E-35 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CIG75_RS06005 fdb0daf179a5e7f3c62d34ad5b626d50 267 SMART SM00967 33 108 3.5E-14 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CIG75_RS06005 fdb0daf179a5e7f3c62d34ad5b626d50 267 Gene3D G3DSA:3.40.1280.10 110 267 1.7E-46 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CIG75_RS06005 fdb0daf179a5e7f3c62d34ad5b626d50 267 Gene3D G3DSA:3.30.1330.30 1 104 1.3E-29 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CIG75_RS06005 fdb0daf179a5e7f3c62d34ad5b626d50 267 SUPERFAMILY SSF55315 5 104 1.18E-27 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CIG75_RS06005 fdb0daf179a5e7f3c62d34ad5b626d50 267 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 34 103 6.7E-15 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CIG75_RS03425 1e092e0d67395b74a63b1cae6a6066e5 905 SUPERFAMILY SSF52540 639 881 2.86E-34 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS03425 1e092e0d67395b74a63b1cae6a6066e5 905 Gene3D G3DSA:3.40.50.300 316 538 3.2E-23 T 28-03-2018 CIG75_RS03425 1e092e0d67395b74a63b1cae6a6066e5 905 Gene3D G3DSA:3.40.50.300 625 803 3.7E-25 T 28-03-2018 CIG75_RS03425 1e092e0d67395b74a63b1cae6a6066e5 905 Gene3D G3DSA:1.10.8.60 804 890 0.0036 T 28-03-2018 CIG75_RS03425 1e092e0d67395b74a63b1cae6a6066e5 905 SUPERFAMILY SSF52540 366 605 2.8E-36 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS03425 1e092e0d67395b74a63b1cae6a6066e5 905 Gene3D G3DSA:1.10.8.60 540 622 0.086 T 28-03-2018 CIG75_RS03425 1e092e0d67395b74a63b1cae6a6066e5 905 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 681 810 4.1E-17 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CIG75_RS03425 1e092e0d67395b74a63b1cae6a6066e5 905 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 406 517 2.9E-16 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CIG75_RS03425 1e092e0d67395b74a63b1cae6a6066e5 905 SMART SM00382 676 814 3.9E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS03425 1e092e0d67395b74a63b1cae6a6066e5 905 SMART SM00382 402 541 2.1E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS03425 1e092e0d67395b74a63b1cae6a6066e5 905 PRINTS PR00819 CbxX/CfqX superfamily signature 799 818 1.2E-48 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CIG75_RS03425 1e092e0d67395b74a63b1cae6a6066e5 905 PRINTS PR00819 CbxX/CfqX superfamily signature 717 731 1.2E-48 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CIG75_RS03425 1e092e0d67395b74a63b1cae6a6066e5 905 PRINTS PR00819 CbxX/CfqX superfamily signature 761 773 1.2E-48 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CIG75_RS03425 1e092e0d67395b74a63b1cae6a6066e5 905 PRINTS PR00819 CbxX/CfqX superfamily signature 731 750 1.2E-48 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CIG75_RS03425 1e092e0d67395b74a63b1cae6a6066e5 905 PRINTS PR00819 CbxX/CfqX superfamily signature 679 694 1.2E-48 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CIG75_RS03425 1e092e0d67395b74a63b1cae6a6066e5 905 PRINTS PR00819 CbxX/CfqX superfamily signature 858 870 1.2E-48 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CIG75_RS03425 1e092e0d67395b74a63b1cae6a6066e5 905 PRINTS PR00819 CbxX/CfqX superfamily signature 639 653 1.2E-48 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CIG75_RS03425 1e092e0d67395b74a63b1cae6a6066e5 905 PRINTS PR00819 CbxX/CfqX superfamily signature 782 799 1.2E-48 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CIG75_RS17595 99e1643415f1d2cef2027f05cc9fcf1b 397 SUPERFAMILY SSF52402 2 203 1.74E-48 T 28-03-2018 CIG75_RS17595 99e1643415f1d2cef2027f05cc9fcf1b 397 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 8 16 - T 28-03-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CIG75_RS17595 99e1643415f1d2cef2027f05cc9fcf1b 397 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 115 126 - T 28-03-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CIG75_RS17595 99e1643415f1d2cef2027f05cc9fcf1b 397 Pfam PF00764 Arginosuccinate synthase 6 390 2.9E-176 T 28-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CIG75_RS17595 99e1643415f1d2cef2027f05cc9fcf1b 397 TIGRFAM TIGR00032 argG: argininosuccinate synthase 4 393 1.9E-166 T 28-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CIG75_RS17595 99e1643415f1d2cef2027f05cc9fcf1b 397 Hamap MF_00005 Argininosuccinate synthase [argG]. 2 395 55.523 T 28-03-2018 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CIG75_RS17595 99e1643415f1d2cef2027f05cc9fcf1b 397 Gene3D G3DSA:3.90.1260.10 157 351 8.9E-94 T 28-03-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CIG75_RS17595 99e1643415f1d2cef2027f05cc9fcf1b 397 Gene3D G3DSA:3.40.50.620 3 156 9.1E-28 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CIG75_RS17595 99e1643415f1d2cef2027f05cc9fcf1b 397 Gene3D G3DSA:1.20.5.470 361 394 4.6E-12 T 28-03-2018 CIG75_RS17595 99e1643415f1d2cef2027f05cc9fcf1b 397 SUPERFAMILY SSF69864 169 395 6.8E-98 T 28-03-2018 CIG75_RS19665 354fa095efb6778fdb241ba34af12fb8 132 ProSitePatterns PS00053 Ribosomal protein S8 signature. 102 119 - T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CIG75_RS19665 354fa095efb6778fdb241ba34af12fb8 132 Gene3D G3DSA:3.30.1370.30 1 67 3.0E-27 T 28-03-2018 CIG75_RS19665 354fa095efb6778fdb241ba34af12fb8 132 SUPERFAMILY SSF56047 2 132 2.75E-50 T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CIG75_RS19665 354fa095efb6778fdb241ba34af12fb8 132 Pfam PF00410 Ribosomal protein S8 5 132 1.4E-54 T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CIG75_RS19665 354fa095efb6778fdb241ba34af12fb8 132 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 132 33.302 T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CIG75_RS19665 354fa095efb6778fdb241ba34af12fb8 132 Gene3D G3DSA:3.30.1490.10 69 130 4.1E-25 T 28-03-2018 CIG75_RS14920 ec42781160a8751a3ec7c4ef0bf3c56e 89 Pfam PF01022 Bacterial regulatory protein, arsR family 12 56 6.1E-16 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CIG75_RS14920 ec42781160a8751a3ec7c4ef0bf3c56e 89 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 54 69 2.0E-15 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CIG75_RS14920 ec42781160a8751a3ec7c4ef0bf3c56e 89 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 7 22 2.0E-15 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CIG75_RS14920 ec42781160a8751a3ec7c4ef0bf3c56e 89 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 39 54 2.0E-15 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CIG75_RS14920 ec42781160a8751a3ec7c4ef0bf3c56e 89 Gene3D G3DSA:1.10.10.10 1 80 4.3E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS14920 ec42781160a8751a3ec7c4ef0bf3c56e 89 SUPERFAMILY SSF46785 3 84 1.68E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS14920 ec42781160a8751a3ec7c4ef0bf3c56e 89 SMART SM00418 5 83 4.3E-29 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CIG75_RS14555 265f6f32b870040b9188ce9940187515 501 Pfam PF01145 SPFH domain / Band 7 family 28 217 2.9E-25 T 28-03-2018 IPR001107 Band 7 domain CIG75_RS14555 265f6f32b870040b9188ce9940187515 501 Pfam PF15975 Flotillin 367 446 1.7E-10 T 28-03-2018 IPR031905 Flotillin, C-terminal domain Reactome: R-HSA-8849932 CIG75_RS14555 265f6f32b870040b9188ce9940187515 501 SMART SM00244 24 202 3.3E-6 T 28-03-2018 IPR001107 Band 7 domain CIG75_RS14555 265f6f32b870040b9188ce9940187515 501 SUPERFAMILY SSF117892 67 209 2.48E-35 T 28-03-2018 IPR001107 Band 7 domain CIG75_RS16525 f592a3aa7a54ce6e2dcd4d474dc8fcc7 265 SMART SM00954 45 165 1.7E-35 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 CIG75_RS16525 f592a3aa7a54ce6e2dcd4d474dc8fcc7 265 SUPERFAMILY SSF81301 5 201 5.72E-55 T 28-03-2018 CIG75_RS16525 f592a3aa7a54ce6e2dcd4d474dc8fcc7 265 Pfam PF04607 Region found in RelA / SpoT proteins 45 163 5.8E-34 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 CIG75_RS16525 f592a3aa7a54ce6e2dcd4d474dc8fcc7 265 Gene3D G3DSA:1.10.287.860 148 196 1.1E-17 T 28-03-2018 CIG75_RS16525 f592a3aa7a54ce6e2dcd4d474dc8fcc7 265 Gene3D G3DSA:3.30.460.10 2 146 7.8E-34 T 28-03-2018 CIG75_RS16180 019b0b73c04af78572e2ab8fb149c11b 125 Hamap MF_00464 S-adenosylmethionine decarboxylase proenzyme [speH]. 4 120 29.877 T 28-03-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 CIG75_RS16180 019b0b73c04af78572e2ab8fb149c11b 125 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 6 116 2.3E-41 T 28-03-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 CIG75_RS16180 019b0b73c04af78572e2ab8fb149c11b 125 Gene3D G3DSA:3.60.90.10 1 125 2.8E-43 T 28-03-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 CIG75_RS16180 019b0b73c04af78572e2ab8fb149c11b 125 Pfam PF02675 S-adenosylmethionine decarboxylase 10 116 2.0E-35 T 28-03-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 CIG75_RS16180 019b0b73c04af78572e2ab8fb149c11b 125 SUPERFAMILY SSF56276 6 118 3.53E-38 T 28-03-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 CIG75_RS11055 dd4fc34f58320a3ff594f1b1a2c842e9 2368 Gene3D G3DSA:1.10.1200.10 2258 2330 1.4E-24 T 28-03-2018 CIG75_RS11055 dd4fc34f58320a3ff594f1b1a2c842e9 2368 SMART SM00823 Phosphopantetheine attachment site 1185 1254 1.5E-7 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS11055 dd4fc34f58320a3ff594f1b1a2c842e9 2368 SMART SM00823 Phosphopantetheine attachment site 2252 2321 1.5E-5 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS11055 dd4fc34f58320a3ff594f1b1a2c842e9 2368 Gene3D G3DSA:3.30.300.30 1070 1190 7.2E-40 T 28-03-2018 CIG75_RS11055 dd4fc34f58320a3ff594f1b1a2c842e9 2368 Gene3D G3DSA:3.30.300.30 2137 2257 4.4E-34 T 28-03-2018 CIG75_RS11055 dd4fc34f58320a3ff594f1b1a2c842e9 2368 SUPERFAMILY SSF52777 1276 1451 1.67E-53 T 28-03-2018 CIG75_RS11055 dd4fc34f58320a3ff594f1b1a2c842e9 2368 Gene3D G3DSA:2.30.38.10 985 1065 1.0E-24 T 28-03-2018 CIG75_RS11055 dd4fc34f58320a3ff594f1b1a2c842e9 2368 Gene3D G3DSA:1.10.1200.10 1191 1250 6.3E-23 T 28-03-2018 CIG75_RS11055 dd4fc34f58320a3ff594f1b1a2c842e9 2368 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1209 1224 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS11055 dd4fc34f58320a3ff594f1b1a2c842e9 2368 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 700 1099 2.6E-134 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS11055 dd4fc34f58320a3ff594f1b1a2c842e9 2368 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1755 2166 1.2E-107 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS11055 dd4fc34f58320a3ff594f1b1a2c842e9 2368 SUPERFAMILY SSF52777 403 667 6.0E-61 T 28-03-2018 CIG75_RS11055 dd4fc34f58320a3ff594f1b1a2c842e9 2368 SUPERFAMILY SSF52777 26 169 2.33E-21 T 28-03-2018 CIG75_RS11055 dd4fc34f58320a3ff594f1b1a2c842e9 2368 SUPERFAMILY SSF47336 1177 1286 2.75E-21 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS11055 dd4fc34f58320a3ff594f1b1a2c842e9 2368 SUPERFAMILY SSF47336 2244 2317 3.14E-20 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS11055 dd4fc34f58320a3ff594f1b1a2c842e9 2368 SUPERFAMILY SSF52777 1458 1703 1.22E-58 T 28-03-2018 CIG75_RS11055 dd4fc34f58320a3ff594f1b1a2c842e9 2368 Gene3D G3DSA:3.40.50.980 1887 2047 1.5E-34 T 28-03-2018 CIG75_RS11055 dd4fc34f58320a3ff594f1b1a2c842e9 2368 Gene3D G3DSA:3.40.50.980 827 984 1.4E-35 T 28-03-2018 CIG75_RS11055 dd4fc34f58320a3ff594f1b1a2c842e9 2368 Pfam PF00668 Condensation domain 26 168 1.8E-17 T 28-03-2018 IPR001242 Condensation domain CIG75_RS11055 dd4fc34f58320a3ff594f1b1a2c842e9 2368 Pfam PF00668 Condensation domain 1274 1710 2.6E-112 T 28-03-2018 IPR001242 Condensation domain CIG75_RS11055 dd4fc34f58320a3ff594f1b1a2c842e9 2368 Pfam PF00668 Condensation domain 218 660 1.3E-118 T 28-03-2018 IPR001242 Condensation domain CIG75_RS11055 dd4fc34f58320a3ff594f1b1a2c842e9 2368 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1882 1893 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS11055 dd4fc34f58320a3ff594f1b1a2c842e9 2368 Pfam PF00501 AMP-binding enzyme 1734 2142 5.9E-84 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS11055 dd4fc34f58320a3ff594f1b1a2c842e9 2368 Pfam PF00501 AMP-binding enzyme 679 1075 4.9E-105 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS11055 dd4fc34f58320a3ff594f1b1a2c842e9 2368 ProSitePatterns PS00455 Putative AMP-binding domain signature. 821 832 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS11055 dd4fc34f58320a3ff594f1b1a2c842e9 2368 Gene3D G3DSA:3.40.50.980 671 826 4.1E-53 T 28-03-2018 CIG75_RS11055 dd4fc34f58320a3ff594f1b1a2c842e9 2368 SUPERFAMILY SSF56801 1727 2264 2.22E-135 T 28-03-2018 CIG75_RS11055 dd4fc34f58320a3ff594f1b1a2c842e9 2368 Pfam PF13193 AMP-binding enzyme C-terminal domain 2150 2225 5.9E-11 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS11055 dd4fc34f58320a3ff594f1b1a2c842e9 2368 Pfam PF13193 AMP-binding enzyme C-terminal domain 1083 1158 1.8E-11 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS11055 dd4fc34f58320a3ff594f1b1a2c842e9 2368 SUPERFAMILY SSF52777 221 395 1.89E-52 T 28-03-2018 CIG75_RS11055 dd4fc34f58320a3ff594f1b1a2c842e9 2368 Gene3D G3DSA:3.40.50.980 1728 1886 1.7E-37 T 28-03-2018 CIG75_RS11055 dd4fc34f58320a3ff594f1b1a2c842e9 2368 Gene3D G3DSA:3.30.559.10 5 206 7.4E-19 T 28-03-2018 CIG75_RS11055 dd4fc34f58320a3ff594f1b1a2c842e9 2368 Gene3D G3DSA:3.30.559.10 1251 1472 1.5E-51 T 28-03-2018 CIG75_RS11055 dd4fc34f58320a3ff594f1b1a2c842e9 2368 Gene3D G3DSA:3.30.559.10 207 419 1.2E-46 T 28-03-2018 CIG75_RS11055 dd4fc34f58320a3ff594f1b1a2c842e9 2368 SUPERFAMILY SSF56801 638 1198 1.15E-167 T 28-03-2018 CIG75_RS11055 dd4fc34f58320a3ff594f1b1a2c842e9 2368 Gene3D G3DSA:2.30.38.10 2053 2135 5.4E-16 T 28-03-2018 CIG75_RS11055 dd4fc34f58320a3ff594f1b1a2c842e9 2368 Pfam PF00550 Phosphopantetheine attachment site 2254 2316 2.3E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS11055 dd4fc34f58320a3ff594f1b1a2c842e9 2368 Pfam PF00550 Phosphopantetheine attachment site 1187 1250 2.9E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS20235 c66ba4019218a1045eef36fc8ea6b625 90 Gene3D G3DSA:4.10.520.10 1 90 8.4E-36 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CIG75_RS20235 c66ba4019218a1045eef36fc8ea6b625 90 SMART SM00411 1 90 4.5E-45 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CIG75_RS20235 c66ba4019218a1045eef36fc8ea6b625 90 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 28-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 CIG75_RS20235 c66ba4019218a1045eef36fc8ea6b625 90 SUPERFAMILY SSF47729 1 89 2.21E-32 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CIG75_RS20235 c66ba4019218a1045eef36fc8ea6b625 90 Pfam PF00216 Bacterial DNA-binding protein 1 89 1.3E-34 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CIG75_RS20235 c66ba4019218a1045eef36fc8ea6b625 90 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 5.2E-18 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CIG75_RS20235 c66ba4019218a1045eef36fc8ea6b625 90 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 5.2E-18 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CIG75_RS20235 c66ba4019218a1045eef36fc8ea6b625 90 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 5.2E-18 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CIG75_RS15395 bfb24e2bcacee851bc99ba58a316c09e 576 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 210 451 2.2E-56 T 28-03-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 CIG75_RS15395 bfb24e2bcacee851bc99ba58a316c09e 576 TIGRFAM TIGR03710 OAFO_sf: 2-oxoacid:acceptor oxidoreductase, alpha subunit 4 571 1.1E-198 T 28-03-2018 IPR022367 2-oxoacid:acceptor oxidoreductase, alpha subunit KEGG: 00020+1.2.7.3|KEGG: 00720+1.2.7.3|MetaCyc: PWY-5392|MetaCyc: PWY-6969 CIG75_RS15395 bfb24e2bcacee851bc99ba58a316c09e 576 Gene3D G3DSA:3.40.50.920 470 576 6.3E-11 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CIG75_RS15395 bfb24e2bcacee851bc99ba58a316c09e 576 SUPERFAMILY SSF52518 198 458 8.34E-61 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CIG75_RS15395 bfb24e2bcacee851bc99ba58a316c09e 576 SUPERFAMILY SSF53323 6 220 6.15E-37 T 28-03-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 CIG75_RS15395 bfb24e2bcacee851bc99ba58a316c09e 576 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 478 567 5.9E-11 T 28-03-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II CIG75_RS15395 bfb24e2bcacee851bc99ba58a316c09e 576 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 14 175 5.3E-37 T 28-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CIG75_RS15395 bfb24e2bcacee851bc99ba58a316c09e 576 Gene3D G3DSA:3.40.50.970 195 469 4.4E-52 T 28-03-2018 CIG75_RS15395 bfb24e2bcacee851bc99ba58a316c09e 576 Gene3D G3DSA:3.40.920.10 2 181 5.6E-38 T 28-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CIG75_RS15395 bfb24e2bcacee851bc99ba58a316c09e 576 SUPERFAMILY SSF52922 469 575 5.71E-16 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CIG75_RS19660 79990da22df907ef7d2c647da279ee9c 179 Pfam PF00347 Ribosomal protein L6 90 164 9.9E-18 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CIG75_RS19660 79990da22df907ef7d2c647da279ee9c 179 Pfam PF00347 Ribosomal protein L6 12 82 1.6E-21 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CIG75_RS19660 79990da22df907ef7d2c647da279ee9c 179 SUPERFAMILY SSF56053 2 82 5.52E-26 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CIG75_RS19660 79990da22df907ef7d2c647da279ee9c 179 SUPERFAMILY SSF56053 83 177 2.13E-33 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CIG75_RS19660 79990da22df907ef7d2c647da279ee9c 179 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 154 162 - T 28-03-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS19660 79990da22df907ef7d2c647da279ee9c 179 PRINTS PR00059 Ribosomal protein L6 signature 99 115 4.1E-34 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CIG75_RS19660 79990da22df907ef7d2c647da279ee9c 179 PRINTS PR00059 Ribosomal protein L6 signature 141 162 4.1E-34 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CIG75_RS19660 79990da22df907ef7d2c647da279ee9c 179 PRINTS PR00059 Ribosomal protein L6 signature 71 96 4.1E-34 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CIG75_RS19660 79990da22df907ef7d2c647da279ee9c 179 Gene3D G3DSA:3.90.930.12 2 82 9.8E-29 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CIG75_RS19660 79990da22df907ef7d2c647da279ee9c 179 PIRSF PIRSF002162 1 177 1.5E-47 T 28-03-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CIG75_RS19660 79990da22df907ef7d2c647da279ee9c 179 Gene3D G3DSA:3.90.930.12 83 178 3.4E-38 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CIG75_RS19660 79990da22df907ef7d2c647da279ee9c 179 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 176 5.9E-73 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CIG75_RS19660 79990da22df907ef7d2c647da279ee9c 179 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 176 37.021 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CIG75_RS00875 17654cac5a4ee4535ab517103c2963d3 226 Pfam PF00834 Ribulose-phosphate 3 epimerase family 3 201 1.4E-64 T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CIG75_RS00875 17654cac5a4ee4535ab517103c2963d3 226 Gene3D G3DSA:3.20.20.70 1 217 7.9E-69 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CIG75_RS00875 17654cac5a4ee4535ab517103c2963d3 226 SUPERFAMILY SSF51366 1 214 2.98E-56 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CIG75_RS00875 17654cac5a4ee4535ab517103c2963d3 226 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 3 214 6.2E-71 T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CIG75_RS00875 17654cac5a4ee4535ab517103c2963d3 226 PIRSF PIRSF001461 1 224 2.4E-75 T 28-03-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CIG75_RS08070 0468ff113ecead5ddda87479c18a784a 344 Gene3D G3DSA:3.30.420.40 4 158 1.6E-41 T 28-03-2018 CIG75_RS08070 0468ff113ecead5ddda87479c18a784a 344 SUPERFAMILY SSF53067 5 146 4.75E-41 T 28-03-2018 CIG75_RS08070 0468ff113ecead5ddda87479c18a784a 344 Gene3D G3DSA:3.90.640.10 195 249 3.7E-33 T 28-03-2018 CIG75_RS08070 0468ff113ecead5ddda87479c18a784a 344 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 5 334 2.9E-158 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CIG75_RS08070 0468ff113ecead5ddda87479c18a784a 344 Pfam PF06723 MreB/Mbl protein 7 331 3.1E-152 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CIG75_RS08070 0468ff113ecead5ddda87479c18a784a 344 SUPERFAMILY SSF53067 147 328 4.02E-53 T 28-03-2018 CIG75_RS08070 0468ff113ecead5ddda87479c18a784a 344 Gene3D G3DSA:3.30.420.40 250 315 3.2E-9 T 28-03-2018 CIG75_RS08070 0468ff113ecead5ddda87479c18a784a 344 Gene3D G3DSA:3.30.420.40 159 194 3.0E-4 T 28-03-2018 CIG75_RS08070 0468ff113ecead5ddda87479c18a784a 344 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 130 149 5.6E-61 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CIG75_RS08070 0468ff113ecead5ddda87479c18a784a 344 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 185 205 5.6E-61 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CIG75_RS08070 0468ff113ecead5ddda87479c18a784a 344 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 64 87 5.6E-61 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CIG75_RS08070 0468ff113ecead5ddda87479c18a784a 344 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 298 324 5.6E-61 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CIG75_RS08070 0468ff113ecead5ddda87479c18a784a 344 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 44 62 5.6E-61 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CIG75_RS00520 7a44d33c751c2fe37e2a958964dee805 430 SMART SM00788 3 422 3.3E-282 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CIG75_RS00520 7a44d33c751c2fe37e2a958964dee805 430 Gene3D G3DSA:3.90.170.10 265 429 2.3E-66 T 28-03-2018 CIG75_RS00520 7a44d33c751c2fe37e2a958964dee805 430 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 131 142 - T 28-03-2018 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CIG75_RS00520 7a44d33c751c2fe37e2a958964dee805 430 Pfam PF00709 Adenylosuccinate synthetase 4 421 2.2E-180 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CIG75_RS00520 7a44d33c751c2fe37e2a958964dee805 430 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 5 422 6.3E-183 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CIG75_RS00520 7a44d33c751c2fe37e2a958964dee805 430 SUPERFAMILY SSF52540 3 424 5.52E-173 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS00520 7a44d33c751c2fe37e2a958964dee805 430 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 28-03-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CIG75_RS00520 7a44d33c751c2fe37e2a958964dee805 430 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 430 204.581 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CIG75_RS00520 7a44d33c751c2fe37e2a958964dee805 430 Gene3D G3DSA:3.40.440.10 1 151 2.5E-53 T 28-03-2018 CIG75_RS00520 7a44d33c751c2fe37e2a958964dee805 430 Gene3D G3DSA:3.40.440.10 152 264 4.1E-24 T 28-03-2018 CIG75_RS06475 517887c94a9cd851fbf07f75b8292b77 624 Pfam PF00183 Hsp90 protein 216 623 9.6E-109 T 28-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 CIG75_RS06475 517887c94a9cd851fbf07f75b8292b77 624 Pfam PF00183 Hsp90 protein 184 228 4.4E-6 T 28-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 CIG75_RS06475 517887c94a9cd851fbf07f75b8292b77 624 PIRSF PIRSF002583 1 624 4.3E-198 T 28-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 CIG75_RS06475 517887c94a9cd851fbf07f75b8292b77 624 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 26 152 3.0E-12 T 28-03-2018 CIG75_RS06475 517887c94a9cd851fbf07f75b8292b77 624 SUPERFAMILY SSF54211 236 488 4.32E-78 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CIG75_RS06475 517887c94a9cd851fbf07f75b8292b77 624 SUPERFAMILY SSF110942 509 623 1.96E-29 T 28-03-2018 CIG75_RS06475 517887c94a9cd851fbf07f75b8292b77 624 Hamap MF_00505 Chaperone protein HtpG [htpG]. 1 624 26.344 T 28-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 CIG75_RS06475 517887c94a9cd851fbf07f75b8292b77 624 PRINTS PR00775 90kDa heat shock protein signature 72 89 7.0E-56 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CIG75_RS06475 517887c94a9cd851fbf07f75b8292b77 624 PRINTS PR00775 90kDa heat shock protein signature 165 182 7.0E-56 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CIG75_RS06475 517887c94a9cd851fbf07f75b8292b77 624 PRINTS PR00775 90kDa heat shock protein signature 2 22 7.0E-56 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CIG75_RS06475 517887c94a9cd851fbf07f75b8292b77 624 PRINTS PR00775 90kDa heat shock protein signature 188 206 7.0E-56 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CIG75_RS06475 517887c94a9cd851fbf07f75b8292b77 624 PRINTS PR00775 90kDa heat shock protein signature 90 107 7.0E-56 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CIG75_RS06475 517887c94a9cd851fbf07f75b8292b77 624 PRINTS PR00775 90kDa heat shock protein signature 23 45 7.0E-56 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CIG75_RS06475 517887c94a9cd851fbf07f75b8292b77 624 PRINTS PR00775 90kDa heat shock protein signature 115 137 7.0E-56 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CIG75_RS06475 517887c94a9cd851fbf07f75b8292b77 624 ProSitePatterns PS00298 Heat shock hsp90 proteins family signature. 22 31 - T 28-03-2018 IPR019805 Heat shock protein Hsp90, conserved site GO:0005524|GO:0006457|GO:0006950|GO:0051082 CIG75_RS06475 517887c94a9cd851fbf07f75b8292b77 624 Gene3D G3DSA:3.30.565.10 26 220 1.7E-54 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS06475 517887c94a9cd851fbf07f75b8292b77 624 SMART SM00387 24 177 0.0016 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS06475 517887c94a9cd851fbf07f75b8292b77 624 SUPERFAMILY SSF55874 1 210 2.62E-63 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS01210 3082e4f93690fd90c9138b1816326d7f 99 Gene3D G3DSA:1.10.700.10 1 88 7.4E-4 T 28-03-2018 IPR011986 Extradiol ring-cleavage dioxygenase LigAB, LigA subunit CIG75_RS17720 61f4b504c0ec607f4ce20dd2821888cb 731 Gene3D G3DSA:1.10.150.310 492 630 4.7E-46 T 28-03-2018 CIG75_RS17720 61f4b504c0ec607f4ce20dd2821888cb 731 Pfam PF16921 Tex protein YqgF-like domain 316 444 2.2E-52 T 28-03-2018 IPR032639 Tex protein, YqgF-like domain CIG75_RS17720 61f4b504c0ec607f4ce20dd2821888cb 731 SUPERFAMILY SSF53098 312 461 5.01E-49 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CIG75_RS17720 61f4b504c0ec607f4ce20dd2821888cb 731 SMART SM00316 649 720 5.9E-25 T 28-03-2018 IPR022967 RNA-binding domain, S1 CIG75_RS17720 61f4b504c0ec607f4ce20dd2821888cb 731 Pfam PF12836 Helix-hairpin-helix motif 484 548 1.7E-24 T 28-03-2018 CIG75_RS17720 61f4b504c0ec607f4ce20dd2821888cb 731 Gene3D G3DSA:3.30.420.140 319 463 6.5E-57 T 28-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 CIG75_RS17720 61f4b504c0ec607f4ce20dd2821888cb 731 Pfam PF00575 S1 RNA binding domain 649 719 4.9E-18 T 28-03-2018 IPR003029 S1 domain GO:0003676 CIG75_RS17720 61f4b504c0ec607f4ce20dd2821888cb 731 SUPERFAMILY SSF47781 463 551 4.56E-24 T 28-03-2018 IPR010994 RuvA domain 2-like CIG75_RS17720 61f4b504c0ec607f4ce20dd2821888cb 731 SUPERFAMILY SSF158832 2 310 1.7E-108 T 28-03-2018 CIG75_RS17720 61f4b504c0ec607f4ce20dd2821888cb 731 SUPERFAMILY SSF50249 635 722 5.89E-25 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CIG75_RS17720 61f4b504c0ec607f4ce20dd2821888cb 731 Pfam PF09371 Tex-like protein N-terminal domain 8 191 3.6E-66 T 28-03-2018 IPR018974 Tex-like protein, N-terminal CIG75_RS17720 61f4b504c0ec607f4ce20dd2821888cb 731 SMART SM00732 316 417 5.7E-33 T 28-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 CIG75_RS17720 61f4b504c0ec607f4ce20dd2821888cb 731 Gene3D G3DSA:1.10.3500.10 109 318 2.0E-57 T 28-03-2018 IPR023323 Tex-like domain CIG75_RS17720 61f4b504c0ec607f4ce20dd2821888cb 731 Gene3D G3DSA:2.40.50.140 640 726 1.3E-25 T 28-03-2018 CIG75_RS17720 61f4b504c0ec607f4ce20dd2821888cb 731 Gene3D G3DSA:1.10.10.650 1 108 2.8E-35 T 28-03-2018 IPR023319 Tex-like protein, HTH domain CIG75_RS17720 61f4b504c0ec607f4ce20dd2821888cb 731 SUPERFAMILY SSF47781 553 632 2.45E-17 T 28-03-2018 IPR010994 RuvA domain 2-like CIG75_RS14095 26694c5325aaf5a8c2c6b69bd613d42d 151 Pfam PF06949 Protein of unknown function (DUF1292) 83 143 1.1E-5 T 28-03-2018 IPR009711 Uncharacterised protein family UPF0473 CIG75_RS13310 04a5b5f44cf3d85cbe3e41ca5a5d6fd7 542 Pfam PF13193 AMP-binding enzyme C-terminal domain 445 520 2.4E-16 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS13310 04a5b5f44cf3d85cbe3e41ca5a5d6fd7 542 Pfam PF00501 AMP-binding enzyme 32 436 2.7E-82 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS13310 04a5b5f44cf3d85cbe3e41ca5a5d6fd7 542 Gene3D G3DSA:3.30.300.30 431 540 1.4E-26 T 28-03-2018 CIG75_RS13310 04a5b5f44cf3d85cbe3e41ca5a5d6fd7 542 Gene3D G3DSA:2.30.38.10 355 430 5.4E-20 T 28-03-2018 CIG75_RS13310 04a5b5f44cf3d85cbe3e41ca5a5d6fd7 542 Gene3D G3DSA:3.40.50.980 22 174 3.6E-32 T 28-03-2018 CIG75_RS13310 04a5b5f44cf3d85cbe3e41ca5a5d6fd7 542 SUPERFAMILY SSF56801 7 530 2.88E-138 T 28-03-2018 CIG75_RS13310 04a5b5f44cf3d85cbe3e41ca5a5d6fd7 542 Gene3D G3DSA:3.40.50.980 175 341 9.1E-34 T 28-03-2018 CIG75_RS13310 04a5b5f44cf3d85cbe3e41ca5a5d6fd7 542 ProSitePatterns PS00455 Putative AMP-binding domain signature. 188 199 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS13310 04a5b5f44cf3d85cbe3e41ca5a5d6fd7 542 TIGRFAM TIGR02275 DHB_AMP_lig: (2,3-dihydroxybenzoyl)adenylate synthase 7 527 2.2E-250 T 28-03-2018 IPR011963 2,3-dihydroxybenzoate-AMP ligase GO:0008668|GO:0019290 CIG75_RS04360 5ad52076c7491b7f374a5516ea801d4f 491 SUPERFAMILY SSF53244 341 487 6.04E-33 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CIG75_RS04360 5ad52076c7491b7f374a5516ea801d4f 491 Pfam PF01225 Mur ligase family, catalytic domain 40 138 8.9E-18 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CIG75_RS04360 5ad52076c7491b7f374a5516ea801d4f 491 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 38 491 32.999 T 28-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CIG75_RS04360 5ad52076c7491b7f374a5516ea801d4f 491 Gene3D G3DSA:3.40.1190.10 130 342 1.5E-39 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CIG75_RS04360 5ad52076c7491b7f374a5516ea801d4f 491 Pfam PF08245 Mur ligase middle domain 146 321 2.0E-27 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CIG75_RS04360 5ad52076c7491b7f374a5516ea801d4f 491 SUPERFAMILY SSF53623 126 340 1.83E-53 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CIG75_RS04360 5ad52076c7491b7f374a5516ea801d4f 491 SUPERFAMILY SSF51984 39 126 3.4E-21 T 28-03-2018 CIG75_RS04360 5ad52076c7491b7f374a5516ea801d4f 491 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 40 486 9.1E-124 T 28-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CIG75_RS04360 5ad52076c7491b7f374a5516ea801d4f 491 Gene3D G3DSA:3.40.50.720 32 127 1.3E-10 T 28-03-2018 CIG75_RS04360 5ad52076c7491b7f374a5516ea801d4f 491 Pfam PF02875 Mur ligase family, glutamate ligase domain 343 424 4.8E-17 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CIG75_RS04360 5ad52076c7491b7f374a5516ea801d4f 491 Gene3D G3DSA:3.90.190.20 343 491 1.7E-29 T 28-03-2018 CIG75_RS05615 b01c0adb9ae1ce6acf5642649ccfbc90 278 SUPERFAMILY SSF57716 224 275 3.71E-15 T 28-03-2018 CIG75_RS05615 b01c0adb9ae1ce6acf5642649ccfbc90 278 Gene3D G3DSA:3.20.190.10 2 133 4.0E-43 T 28-03-2018 CIG75_RS05615 b01c0adb9ae1ce6acf5642649ccfbc90 278 SUPERFAMILY SSF46946 134 224 2.62E-28 T 28-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CIG75_RS05615 b01c0adb9ae1ce6acf5642649ccfbc90 278 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 274 2.4E-101 T 28-03-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 CIG75_RS05615 b01c0adb9ae1ce6acf5642649ccfbc90 278 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 134 224 4.0E-28 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CIG75_RS05615 b01c0adb9ae1ce6acf5642649ccfbc90 278 SUPERFAMILY SSF81624 2 139 2.22E-42 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CIG75_RS05615 b01c0adb9ae1ce6acf5642649ccfbc90 278 ProSitePatterns PS01242 Zinc finger FPG-type signature. 250 274 - T 28-03-2018 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 CIG75_RS05615 b01c0adb9ae1ce6acf5642649ccfbc90 278 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 2 117 3.1E-33 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CIG75_RS05615 b01c0adb9ae1ce6acf5642649ccfbc90 278 Pfam PF06827 Zinc finger found in FPG and IleRS 249 275 9.8E-10 T 28-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 CIG75_RS05615 b01c0adb9ae1ce6acf5642649ccfbc90 278 SMART SM00898 2 118 2.8E-50 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CIG75_RS05615 b01c0adb9ae1ce6acf5642649ccfbc90 278 Gene3D G3DSA:1.10.8.50 135 278 1.7E-48 T 28-03-2018 CIG75_RS05615 b01c0adb9ae1ce6acf5642649ccfbc90 278 SMART SM01232 134 227 2.5E-45 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CIG75_RS05615 b01c0adb9ae1ce6acf5642649ccfbc90 278 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 275 42.187 T 28-03-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 CIG75_RS20430 d199e01808dfb7e59c44d92a720ace1c 288 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 20 284 5.8E-83 T 28-03-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 CIG75_RS20430 d199e01808dfb7e59c44d92a720ace1c 288 SUPERFAMILY SSF53335 17 286 2.17E-72 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CIG75_RS20430 d199e01808dfb7e59c44d92a720ace1c 288 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 20 286 54.667 T 28-03-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 CIG75_RS20430 d199e01808dfb7e59c44d92a720ace1c 288 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 52 79 - T 28-03-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 CIG75_RS20430 d199e01808dfb7e59c44d92a720ace1c 288 Pfam PF00398 Ribosomal RNA adenine dimethylase 20 273 9.0E-66 T 28-03-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm CIG75_RS20430 d199e01808dfb7e59c44d92a720ace1c 288 Gene3D G3DSA:1.10.8.100 225 285 2.2E-23 T 28-03-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 CIG75_RS20430 d199e01808dfb7e59c44d92a720ace1c 288 Gene3D G3DSA:3.40.50.150 11 224 9.2E-58 T 28-03-2018 CIG75_RS20430 d199e01808dfb7e59c44d92a720ace1c 288 SMART SM00650 36 211 8.2E-77 T 28-03-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 CIG75_RS08550 2db7ff06e29eed749ebdae5df7cdf049 113 Pfam PF12647 RNHCP domain 9 92 1.8E-30 T 28-03-2018 IPR024439 RNHCP domain CIG75_RS15670 e3f6195b22bb9adf56a39693ad7d6e6c 642 SMART SM00091 172 239 0.013 T 28-03-2018 IPR000014 PAS domain CIG75_RS15670 e3f6195b22bb9adf56a39693ad7d6e6c 642 SMART SM00091 297 364 1.3E-4 T 28-03-2018 IPR000014 PAS domain CIG75_RS15670 e3f6195b22bb9adf56a39693ad7d6e6c 642 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 297 418 1.8E-9 T 28-03-2018 IPR000014 PAS domain CIG75_RS15670 e3f6195b22bb9adf56a39693ad7d6e6c 642 SUPERFAMILY SSF55785 172 280 7.85E-11 T 28-03-2018 IPR000014 PAS domain CIG75_RS15670 e3f6195b22bb9adf56a39693ad7d6e6c 642 SMART SM00388 427 494 7.3E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CIG75_RS15670 e3f6195b22bb9adf56a39693ad7d6e6c 642 Gene3D G3DSA:3.30.450.20 159 288 1.6E-9 T 28-03-2018 CIG75_RS15670 e3f6195b22bb9adf56a39693ad7d6e6c 642 Pfam PF00512 His Kinase A (phospho-acceptor) domain 429 493 3.8E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CIG75_RS15670 e3f6195b22bb9adf56a39693ad7d6e6c 642 SUPERFAMILY SSF55874 484 640 1.02E-39 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS15670 e3f6195b22bb9adf56a39693ad7d6e6c 642 Pfam PF08448 PAS fold 178 283 4.2E-11 T 28-03-2018 IPR013656 PAS fold-4 CIG75_RS15670 e3f6195b22bb9adf56a39693ad7d6e6c 642 Pfam PF13426 PAS domain 309 411 9.9E-9 T 28-03-2018 IPR000014 PAS domain CIG75_RS15670 e3f6195b22bb9adf56a39693ad7d6e6c 642 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 537 641 4.5E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS15670 e3f6195b22bb9adf56a39693ad7d6e6c 642 SUPERFAMILY SSF47384 422 494 2.94E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CIG75_RS15670 e3f6195b22bb9adf56a39693ad7d6e6c 642 SMART SM00387 536 642 1.2E-31 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS15670 e3f6195b22bb9adf56a39693ad7d6e6c 642 Gene3D G3DSA:3.30.565.10 495 642 3.9E-42 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS15670 e3f6195b22bb9adf56a39693ad7d6e6c 642 Gene3D G3DSA:3.30.450.20 289 419 1.2E-16 T 28-03-2018 CIG75_RS15670 e3f6195b22bb9adf56a39693ad7d6e6c 642 Gene3D G3DSA:1.10.287.130 420 490 1.7E-10 T 28-03-2018 CIG75_RS15670 e3f6195b22bb9adf56a39693ad7d6e6c 642 SUPERFAMILY SSF55785 290 405 5.23E-13 T 28-03-2018 IPR000014 PAS domain CIG75_RS15670 e3f6195b22bb9adf56a39693ad7d6e6c 642 PRINTS PR00344 Bacterial sensor protein C-terminal signature 591 601 1.7E-18 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS15670 e3f6195b22bb9adf56a39693ad7d6e6c 642 PRINTS PR00344 Bacterial sensor protein C-terminal signature 602 620 1.7E-18 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS15670 e3f6195b22bb9adf56a39693ad7d6e6c 642 PRINTS PR00344 Bacterial sensor protein C-terminal signature 626 639 1.7E-18 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS15670 e3f6195b22bb9adf56a39693ad7d6e6c 642 PRINTS PR00344 Bacterial sensor protein C-terminal signature 573 587 1.7E-18 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS10165 e1e967694611fd8e380ed262ad75ebdf 307 Gene3D G3DSA:3.40.50.1820 4 288 3.3E-31 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS10165 e1e967694611fd8e380ed262ad75ebdf 307 SUPERFAMILY SSF53474 111 228 1.44E-38 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS10165 e1e967694611fd8e380ed262ad75ebdf 307 SUPERFAMILY SSF53474 267 307 1.44E-38 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS10165 e1e967694611fd8e380ed262ad75ebdf 307 Pfam PF10503 Esterase PHB depolymerase 25 228 5.1E-60 T 28-03-2018 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 CIG75_RS10165 e1e967694611fd8e380ed262ad75ebdf 307 TIGRFAM TIGR01840 esterase_phb: esterase, PHB depolymerase family 25 227 1.7E-48 T 28-03-2018 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 CIG75_RS10165 e1e967694611fd8e380ed262ad75ebdf 307 SUPERFAMILY SSF53474 16 113 1.9E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS14700 8a78ae1a85b0534ddbce2fd574ee931f 250 SUPERFAMILY SSF50249 3 79 2.57E-18 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CIG75_RS14700 8a78ae1a85b0534ddbce2fd574ee931f 250 TIGRFAM TIGR00613 reco: DNA repair protein RecO 3 245 5.4E-65 T 28-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 CIG75_RS14700 8a78ae1a85b0534ddbce2fd574ee931f 250 Pfam PF11967 Recombination protein O N terminal 3 79 1.2E-22 T 28-03-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal CIG75_RS14700 8a78ae1a85b0534ddbce2fd574ee931f 250 SUPERFAMILY SSF57863 82 233 1.26E-41 T 28-03-2018 CIG75_RS14700 8a78ae1a85b0534ddbce2fd574ee931f 250 Hamap MF_00201 DNA repair protein RecO [recO]. 1 245 28.504 T 28-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 CIG75_RS14700 8a78ae1a85b0534ddbce2fd574ee931f 250 Pfam PF02565 Recombination protein O C terminal 83 239 1.2E-36 T 28-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 CIG75_RS14700 8a78ae1a85b0534ddbce2fd574ee931f 250 Gene3D G3DSA:2.40.50.140 1 82 4.3E-22 T 28-03-2018 CIG75_RS17190 78894456af54c2a533e65ba724532335 314 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 137 157 - T 28-03-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 CIG75_RS17190 78894456af54c2a533e65ba724532335 314 Gene3D G3DSA:3.50.50.60 130 185 7.6E-12 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS17190 78894456af54c2a533e65ba724532335 314 Gene3D G3DSA:3.50.50.60 186 304 1.2E-14 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS17190 78894456af54c2a533e65ba724532335 314 Gene3D G3DSA:3.50.50.60 1 129 4.9E-26 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS17190 78894456af54c2a533e65ba724532335 314 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 4.5E-39 T 28-03-2018 CIG75_RS17190 78894456af54c2a533e65ba724532335 314 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 233 249 4.5E-39 T 28-03-2018 CIG75_RS17190 78894456af54c2a533e65ba724532335 314 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 107 125 4.5E-39 T 28-03-2018 CIG75_RS17190 78894456af54c2a533e65ba724532335 314 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 149 167 4.5E-39 T 28-03-2018 CIG75_RS17190 78894456af54c2a533e65ba724532335 314 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 259 281 4.5E-39 T 28-03-2018 CIG75_RS17190 78894456af54c2a533e65ba724532335 314 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 295 3.1E-55 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS17190 78894456af54c2a533e65ba724532335 314 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 62 72 4.1E-68 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CIG75_RS17190 78894456af54c2a533e65ba724532335 314 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 108 116 4.1E-68 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CIG75_RS17190 78894456af54c2a533e65ba724532335 314 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 145 169 4.1E-68 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CIG75_RS17190 78894456af54c2a533e65ba724532335 314 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 9 31 4.1E-68 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CIG75_RS17190 78894456af54c2a533e65ba724532335 314 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 235 256 4.1E-68 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CIG75_RS17190 78894456af54c2a533e65ba724532335 314 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 197 213 4.1E-68 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CIG75_RS17190 78894456af54c2a533e65ba724532335 314 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 130 142 4.1E-68 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CIG75_RS17190 78894456af54c2a533e65ba724532335 314 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 42 57 4.1E-68 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CIG75_RS17190 78894456af54c2a533e65ba724532335 314 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 269 287 4.1E-68 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CIG75_RS17190 78894456af54c2a533e65ba724532335 314 SUPERFAMILY SSF51905 4 302 1.3E-56 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS17190 78894456af54c2a533e65ba724532335 314 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 8 306 4.0E-119 T 28-03-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 CIG75_RS04195 3e6d99ff51f5aed6cf0a1bdb86e44e48 222 PIRSF PIRSF032442 21 222 2.4E-62 T 28-03-2018 IPR016997 Uncharacterised conserved protein UCP032442 CIG75_RS04195 3e6d99ff51f5aed6cf0a1bdb86e44e48 222 Gene3D G3DSA:3.90.70.10 40 222 4.3E-22 T 28-03-2018 CIG75_RS04195 3e6d99ff51f5aed6cf0a1bdb86e44e48 222 Pfam PF13529 Peptidase_C39 like family 31 194 3.6E-34 T 28-03-2018 CIG75_RS03930 0f6f57bffe30574cc8e3a2592b697485 193 Pfam PF00561 alpha/beta hydrolase fold 1 51 3.5E-9 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CIG75_RS03930 0f6f57bffe30574cc8e3a2592b697485 193 PRINTS PR00111 Alpha/beta hydrolase fold signature 25 38 2.5E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CIG75_RS03930 0f6f57bffe30574cc8e3a2592b697485 193 PRINTS PR00111 Alpha/beta hydrolase fold signature 11 24 2.5E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CIG75_RS03930 0f6f57bffe30574cc8e3a2592b697485 193 PRINTS PR00111 Alpha/beta hydrolase fold signature 136 150 2.5E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CIG75_RS03930 0f6f57bffe30574cc8e3a2592b697485 193 Gene3D G3DSA:3.40.50.1820 1 192 5.7E-29 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS03930 0f6f57bffe30574cc8e3a2592b697485 193 SUPERFAMILY SSF53474 1 186 6.8E-42 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS13735 23b24a3b7c2d80d9d5bbc8160cbb58f7 709 Gene3D G3DSA:3.40.50.300 290 391 4.5E-26 T 28-03-2018 CIG75_RS13735 23b24a3b7c2d80d9d5bbc8160cbb58f7 709 TIGRFAM TIGR01073 pcrA: ATP-dependent DNA helicase PcrA 13 646 7.6E-278 T 28-03-2018 IPR005751 ATP-dependent DNA helicase PcrA GO:0004003|GO:0005737|GO:0006268 CIG75_RS13735 23b24a3b7c2d80d9d5bbc8160cbb58f7 709 SUPERFAMILY SSF52540 9 645 7.09E-174 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS13735 23b24a3b7c2d80d9d5bbc8160cbb58f7 709 Gene3D G3DSA:3.40.50.300 452 658 2.6E-46 T 28-03-2018 CIG75_RS13735 23b24a3b7c2d80d9d5bbc8160cbb58f7 709 Gene3D G3DSA:3.40.50.300 149 289 1.5E-34 T 28-03-2018 CIG75_RS13735 23b24a3b7c2d80d9d5bbc8160cbb58f7 709 Gene3D G3DSA:3.40.50.300 8 148 9.1E-30 T 28-03-2018 CIG75_RS13735 23b24a3b7c2d80d9d5bbc8160cbb58f7 709 Pfam PF13361 UvrD-like helicase C-terminal domain 284 616 1.2E-73 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CIG75_RS13735 23b24a3b7c2d80d9d5bbc8160cbb58f7 709 Pfam PF00580 UvrD/REP helicase N-terminal domain 15 279 2.1E-82 T 28-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 CIG75_RS17995 7fd2aa36c8053b3ee54c43ce15d3b408 338 SMART SM00382 49 248 3.8E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS17995 7fd2aa36c8053b3ee54c43ce15d3b408 338 Pfam PF00005 ABC transporter 41 184 6.9E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS17995 7fd2aa36c8053b3ee54c43ce15d3b408 338 SUPERFAMILY SSF52540 35 254 1.93E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS17995 7fd2aa36c8053b3ee54c43ce15d3b408 338 Gene3D G3DSA:3.40.50.300 1 294 1.1E-53 T 28-03-2018 CIG75_RS04950 ca7402f5e089660f3b1fdf671f011c9c 363 Gene3D G3DSA:1.10.1670.10 127 233 1.9E-39 T 28-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CIG75_RS04950 ca7402f5e089660f3b1fdf671f011c9c 363 Gene3D G3DSA:1.10.340.30 30 126 1.8E-35 T 28-03-2018 CIG75_RS04950 ca7402f5e089660f3b1fdf671f011c9c 363 SUPERFAMILY SSF55811 229 359 9.07E-33 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CIG75_RS04950 ca7402f5e089660f3b1fdf671f011c9c 363 SMART SM00525 200 220 0.0036 T 28-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 CIG75_RS04950 ca7402f5e089660f3b1fdf671f011c9c 363 TIGRFAM TIGR01084 mutY: A/G-specific adenine glycosylase 19 279 4.2E-103 T 28-03-2018 IPR005760 A/G-specific adenine glycosylase MutY GO:0006284|GO:0019104 CIG75_RS04950 ca7402f5e089660f3b1fdf671f011c9c 363 SMART SM00478 48 199 4.5E-57 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CIG75_RS04950 ca7402f5e089660f3b1fdf671f011c9c 363 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 201 217 - T 28-03-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CIG75_RS04950 ca7402f5e089660f3b1fdf671f011c9c 363 Gene3D G3DSA:3.90.79.10 234 360 2.8E-29 T 28-03-2018 CIG75_RS04950 ca7402f5e089660f3b1fdf671f011c9c 363 ProSitePatterns PS01155 Endonuclease III family signature. 111 140 - T 28-03-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 CIG75_RS04950 ca7402f5e089660f3b1fdf671f011c9c 363 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 44 175 2.5E-20 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CIG75_RS04950 ca7402f5e089660f3b1fdf671f011c9c 363 SUPERFAMILY SSF48150 18 234 2.83E-77 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CIG75_RS04950 ca7402f5e089660f3b1fdf671f011c9c 363 Pfam PF14815 NUDIX domain 244 357 1.7E-26 T 28-03-2018 IPR029119 MutY, C-terminal Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CIG75_RS04950 ca7402f5e089660f3b1fdf671f011c9c 363 Pfam PF00633 Helix-hairpin-helix motif 109 137 1.7E-9 T 28-03-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 CIG75_RS04625 8da2892f87179da5ac60f9ebe71fb542 1022 Gene3D G3DSA:3.30.2090.10 704 791 4.9E-10 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CIG75_RS04625 8da2892f87179da5ac60f9ebe71fb542 1022 Gene3D G3DSA:3.30.2090.10 176 275 6.1E-14 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CIG75_RS04625 8da2892f87179da5ac60f9ebe71fb542 1022 PRINTS PR00702 Acriflavin resistance protein family signature 11 35 1.4E-49 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CIG75_RS04625 8da2892f87179da5ac60f9ebe71fb542 1022 PRINTS PR00702 Acriflavin resistance protein family signature 471 494 1.4E-49 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CIG75_RS04625 8da2892f87179da5ac60f9ebe71fb542 1022 PRINTS PR00702 Acriflavin resistance protein family signature 335 358 1.4E-49 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CIG75_RS04625 8da2892f87179da5ac60f9ebe71fb542 1022 PRINTS PR00702 Acriflavin resistance protein family signature 446 469 1.4E-49 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CIG75_RS04625 8da2892f87179da5ac60f9ebe71fb542 1022 PRINTS PR00702 Acriflavin resistance protein family signature 39 57 1.4E-49 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CIG75_RS04625 8da2892f87179da5ac60f9ebe71fb542 1022 PRINTS PR00702 Acriflavin resistance protein family signature 390 414 1.4E-49 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CIG75_RS04625 8da2892f87179da5ac60f9ebe71fb542 1022 PRINTS PR00702 Acriflavin resistance protein family signature 362 383 1.4E-49 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CIG75_RS04625 8da2892f87179da5ac60f9ebe71fb542 1022 SUPERFAMILY SSF82693 41 126 2.96E-19 T 28-03-2018 CIG75_RS04625 8da2892f87179da5ac60f9ebe71fb542 1022 SUPERFAMILY SSF82866 791 1012 1.57E-49 T 28-03-2018 CIG75_RS04625 8da2892f87179da5ac60f9ebe71fb542 1022 Pfam PF00873 AcrB/AcrD/AcrF family 6 1008 8.0E-201 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CIG75_RS04625 8da2892f87179da5ac60f9ebe71fb542 1022 Gene3D G3DSA:3.30.70.1430 41 140 1.2E-21 T 28-03-2018 CIG75_RS04625 8da2892f87179da5ac60f9ebe71fb542 1022 SUPERFAMILY SSF82714 180 242 9.16E-7 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CIG75_RS04625 8da2892f87179da5ac60f9ebe71fb542 1022 Gene3D G3DSA:3.30.70.1430 558 656 1.1E-7 T 28-03-2018 CIG75_RS04625 8da2892f87179da5ac60f9ebe71fb542 1022 Gene3D G3DSA:1.20.1640.10 792 1012 2.4E-42 T 28-03-2018 CIG75_RS04625 8da2892f87179da5ac60f9ebe71fb542 1022 Gene3D G3DSA:1.20.1640.10 276 501 1.9E-46 T 28-03-2018 CIG75_RS04625 8da2892f87179da5ac60f9ebe71fb542 1022 SUPERFAMILY SSF82866 299 495 5.62E-43 T 28-03-2018 CIG75_RS08340 8138f764a228fc9f6ee2fd46eb7bf1a5 342 Pfam PF00899 ThiF family 6 245 1.0E-62 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CIG75_RS08340 8138f764a228fc9f6ee2fd46eb7bf1a5 342 SUPERFAMILY SSF69572 2 332 7.32E-86 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CIG75_RS08340 8138f764a228fc9f6ee2fd46eb7bf1a5 342 Gene3D G3DSA:3.40.50.720 1 248 3.7E-64 T 28-03-2018 CIG75_RS08520 3f5b451cbbaa1e209b9d1c4217ae5d7b 394 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 87 96 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CIG75_RS08520 3f5b451cbbaa1e209b9d1c4217ae5d7b 394 SUPERFAMILY SSF55031 196 300 2.21E-20 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CIG75_RS08520 3f5b451cbbaa1e209b9d1c4217ae5d7b 394 Gene3D G3DSA:3.40.630.10 1 389 2.9E-66 T 28-03-2018 CIG75_RS08520 3f5b451cbbaa1e209b9d1c4217ae5d7b 394 PIRSF PIRSF001123 5 63 0.11 T 28-03-2018 IPR008007 Peptidase M42 CIG75_RS08520 3f5b451cbbaa1e209b9d1c4217ae5d7b 394 PIRSF PIRSF001123 305 393 0.0012 T 28-03-2018 IPR008007 Peptidase M42 CIG75_RS08520 3f5b451cbbaa1e209b9d1c4217ae5d7b 394 PIRSF PIRSF001123 112 205 6.1E-6 T 28-03-2018 IPR008007 Peptidase M42 CIG75_RS08520 3f5b451cbbaa1e209b9d1c4217ae5d7b 394 PIRSF PIRSF001123 55 112 1.3 T 28-03-2018 IPR008007 Peptidase M42 CIG75_RS08520 3f5b451cbbaa1e209b9d1c4217ae5d7b 394 Pfam PF01546 Peptidase family M20/M25/M40 88 383 3.9E-19 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CIG75_RS08520 3f5b451cbbaa1e209b9d1c4217ae5d7b 394 SUPERFAMILY SSF53187 303 387 5.28E-61 T 28-03-2018 CIG75_RS08520 3f5b451cbbaa1e209b9d1c4217ae5d7b 394 SUPERFAMILY SSF53187 6 192 5.28E-61 T 28-03-2018 CIG75_RS08520 3f5b451cbbaa1e209b9d1c4217ae5d7b 394 TIGRFAM TIGR01883 PepT-like: peptidase T-like protein 8 382 6.2E-108 T 28-03-2018 IPR010162 Peptidase M20B, peptidase T-like CIG75_RS08520 3f5b451cbbaa1e209b9d1c4217ae5d7b 394 Pfam PF07687 Peptidase dimerisation domain 196 283 2.1E-17 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CIG75_RS15455 a53dac77863fc380fc0254e0efa824ae 376 SUPERFAMILY SSF55031 183 274 1.96E-19 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CIG75_RS15455 a53dac77863fc380fc0254e0efa824ae 376 Pfam PF07687 Peptidase dimerisation domain 181 273 5.2E-16 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CIG75_RS15455 a53dac77863fc380fc0254e0efa824ae 376 Pfam PF01546 Peptidase family M20/M25/M40 79 373 4.5E-26 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CIG75_RS15455 a53dac77863fc380fc0254e0efa824ae 376 SUPERFAMILY SSF53187 4 192 2.66E-49 T 28-03-2018 CIG75_RS15455 a53dac77863fc380fc0254e0efa824ae 376 SUPERFAMILY SSF53187 302 374 2.66E-49 T 28-03-2018 CIG75_RS15455 a53dac77863fc380fc0254e0efa824ae 376 Gene3D G3DSA:3.40.630.10 10 376 2.7E-48 T 28-03-2018 CIG75_RS15455 a53dac77863fc380fc0254e0efa824ae 376 PIRSF PIRSF037238 4 376 5.4E-117 T 28-03-2018 IPR017150 Peptidase M20, glutamate carboxypeptidase CIG75_RS09135 3a8614e5364fd4bc72b35abf2b443754 187 Gene3D G3DSA:1.10.286.10 6 54 2.6E-22 T 28-03-2018 CIG75_RS09135 3a8614e5364fd4bc72b35abf2b443754 187 Pfam PF01227 GTP cyclohydrolase I 9 185 1.1E-75 T 28-03-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CIG75_RS09135 3a8614e5364fd4bc72b35abf2b443754 187 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 4 186 40.803 T 28-03-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CIG75_RS09135 3a8614e5364fd4bc72b35abf2b443754 187 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 64 80 - T 28-03-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CIG75_RS09135 3a8614e5364fd4bc72b35abf2b443754 187 Gene3D G3DSA:3.30.1130.10 55 187 1.9E-57 T 28-03-2018 CIG75_RS09135 3a8614e5364fd4bc72b35abf2b443754 187 SUPERFAMILY SSF55620 3 186 4.3E-74 T 28-03-2018 CIG75_RS09135 3a8614e5364fd4bc72b35abf2b443754 187 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 9 186 4.7E-73 T 28-03-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 SUPERFAMILY SSF52777 190 458 1.89E-51 T 28-03-2018 CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 SUPERFAMILY SSF56801 2524 3072 5.63E-163 T 28-03-2018 CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 SUPERFAMILY SSF56801 3570 4116 1.31E-160 T 28-03-2018 CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 SUPERFAMILY SSF53474 4169 4428 4.1E-63 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 SUPERFAMILY SSF52777 1055 1232 2.22E-54 T 28-03-2018 CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 SUPERFAMILY SSF56801 1476 2025 9.16E-165 T 28-03-2018 CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 SUPERFAMILY SSF47336 3053 3160 1.44E-18 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1657 1668 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 SUPERFAMILY SSF52777 2287 2550 1.45E-68 T 28-03-2018 CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 Pfam PF00668 Condensation domain 8 450 7.6E-97 T 28-03-2018 IPR001242 Condensation domain CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 Pfam PF00668 Condensation domain 1051 1497 2.4E-122 T 28-03-2018 IPR001242 Condensation domain CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 Pfam PF00668 Condensation domain 2099 2544 1.5E-120 T 28-03-2018 IPR001242 Condensation domain CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 Pfam PF00668 Condensation domain 3145 3591 5.3E-117 T 28-03-2018 IPR001242 Condensation domain CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4127 4142 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 Gene3D G3DSA:1.10.1200.10 4111 4176 3.6E-20 T 28-03-2018 CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 Pfam PF00550 Phosphopantetheine attachment site 2014 2077 8.1E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 Pfam PF00550 Phosphopantetheine attachment site 4106 4168 1.8E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 Pfam PF00550 Phosphopantetheine attachment site 3061 3121 2.9E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 Pfam PF00550 Phosphopantetheine attachment site 968 1031 1.8E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 Gene3D G3DSA:3.30.559.10 3 208 2.2E-38 T 28-03-2018 CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 Gene3D G3DSA:3.30.559.10 1037 1254 6.2E-51 T 28-03-2018 CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 SUPERFAMILY SSF47336 4096 4169 2.09E-18 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 Pfam PF00975 Thioesterase domain 4189 4421 2.2E-36 T 28-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 Gene3D G3DSA:1.10.1200.10 2019 2084 5.5E-23 T 28-03-2018 CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 Gene3D G3DSA:3.40.50.980 463 619 2.7E-42 T 28-03-2018 CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 Gene3D G3DSA:3.40.50.980 3602 3755 4.5E-50 T 28-03-2018 CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 Gene3D G3DSA:3.40.50.980 2555 2709 2.1E-51 T 28-03-2018 CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 Gene3D G3DSA:3.40.50.980 1508 1662 4.0E-50 T 28-03-2018 CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 SUPERFAMILY SSF56801 431 978 1.31E-147 T 28-03-2018 CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 SUPERFAMILY SSF52777 3150 3327 5.78E-50 T 28-03-2018 CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 SUPERFAMILY SSF52777 1239 1480 4.11E-70 T 28-03-2018 CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 Gene3D G3DSA:3.40.50.980 3756 3905 1.7E-33 T 28-03-2018 CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 Gene3D G3DSA:3.40.50.980 2710 2862 1.0E-34 T 28-03-2018 CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 Gene3D G3DSA:3.40.50.980 1663 1813 6.7E-37 T 28-03-2018 CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 Gene3D G3DSA:3.40.50.980 620 770 7.4E-22 T 28-03-2018 CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 Gene3D G3DSA:2.30.38.10 3906 3985 1.2E-25 T 28-03-2018 CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 Gene3D G3DSA:2.30.38.10 776 855 8.7E-24 T 28-03-2018 CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 Gene3D G3DSA:2.30.38.10 1815 1894 9.5E-24 T 28-03-2018 CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 Gene3D G3DSA:2.30.38.10 2863 2941 3.1E-23 T 28-03-2018 CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 Gene3D G3DSA:1.10.1200.10 3065 3130 1.4E-21 T 28-03-2018 CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 Gene3D G3DSA:1.10.1200.10 972 1036 2.2E-22 T 28-03-2018 CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2704 2715 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 Pfam PF13193 AMP-binding enzyme C-terminal domain 4000 4075 3.9E-14 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 Pfam PF13193 AMP-binding enzyme C-terminal domain 2956 3031 7.8E-13 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 Pfam PF13193 AMP-binding enzyme C-terminal domain 1909 1984 3.1E-14 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 Pfam PF13193 AMP-binding enzyme C-terminal domain 870 938 2.4E-10 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 SUPERFAMILY SSF47336 2006 2113 7.46E-20 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 ProSitePatterns PS00455 Putative AMP-binding domain signature. 3750 3761 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 SUPERFAMILY SSF52777 2103 2280 2.0E-53 T 28-03-2018 CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 ProSitePatterns PS00455 Putative AMP-binding domain signature. 614 625 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 SUPERFAMILY SSF52777 3335 3594 3.89E-67 T 28-03-2018 CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 SMART SM00823 Phosphopantetheine attachment site 3059 3128 3.5E-4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 SMART SM00823 Phosphopantetheine attachment site 4103 4172 0.0011 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 SMART SM00823 Phosphopantetheine attachment site 2012 2081 2.7E-6 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 SMART SM00823 Phosphopantetheine attachment site 966 1035 3.5E-4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 Gene3D G3DSA:3.40.50.1820 4177 4432 6.8E-28 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1538 1925 1.1E-140 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2585 2972 4.8E-135 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 493 886 2.3E-119 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 3632 4016 3.5E-133 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 Pfam PF00501 AMP-binding enzyme 1517 1901 3.3E-108 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 Pfam PF00501 AMP-binding enzyme 3612 3992 1.8E-104 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 Pfam PF00501 AMP-binding enzyme 473 862 3.0E-86 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 Pfam PF00501 AMP-binding enzyme 2564 2948 5.4E-104 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 SUPERFAMILY SSF47336 961 1032 1.57E-18 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 Gene3D G3DSA:3.30.300.30 1897 2018 2.5E-39 T 28-03-2018 CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 Gene3D G3DSA:3.30.300.30 3987 4110 8.2E-40 T 28-03-2018 CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 Gene3D G3DSA:3.30.300.30 856 971 7.8E-36 T 28-03-2018 CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 Gene3D G3DSA:3.30.300.30 2944 3064 2.6E-38 T 28-03-2018 CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 SUPERFAMILY SSF52777 12 189 1.56E-46 T 28-03-2018 CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 Gene3D G3DSA:3.30.559.10 2085 2285 1.4E-45 T 28-03-2018 CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 Gene3D G3DSA:3.30.559.10 3131 3332 8.0E-44 T 28-03-2018 CIG75_RS06630 6c5d6dd279083fd8ce6496f0dfef19c2 4438 SMART SM00824 Thioesterase 4191 4428 4.4E-6 T 28-03-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 CIG75_RS01710 33e49b777ac315ea305587492f27773c 254 SUPERFAMILY SSF53067 1 122 3.59E-38 T 28-03-2018 CIG75_RS01710 33e49b777ac315ea305587492f27773c 254 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 3 249 1.5E-80 T 28-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CIG75_RS01710 33e49b777ac315ea305587492f27773c 254 Gene3D G3DSA:3.30.420.40 89 254 1.5E-61 T 28-03-2018 CIG75_RS01710 33e49b777ac315ea305587492f27773c 254 Hamap MF_01274 Type III pantothenate kinase [coaX]. 1 254 36.94 T 28-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CIG75_RS01710 33e49b777ac315ea305587492f27773c 254 Pfam PF03309 Type III pantothenate kinase 2 205 4.1E-72 T 28-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CIG75_RS01710 33e49b777ac315ea305587492f27773c 254 SUPERFAMILY SSF53067 124 253 1.2E-38 T 28-03-2018 CIG75_RS02125 0ffc8a1c5fb99f8cd61bf7b45d983631 492 SMART SM00228 93 165 8.8E-14 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CIG75_RS02125 0ffc8a1c5fb99f8cd61bf7b45d983631 492 Pfam PF03572 Peptidase family S41 192 350 5.3E-43 T 28-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 CIG75_RS02125 0ffc8a1c5fb99f8cd61bf7b45d983631 492 SUPERFAMILY SSF50156 93 175 6.92E-16 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CIG75_RS02125 0ffc8a1c5fb99f8cd61bf7b45d983631 492 Gene3D G3DSA:3.90.226.10 178 368 5.2E-52 T 28-03-2018 CIG75_RS02125 0ffc8a1c5fb99f8cd61bf7b45d983631 492 SMART SM00245 166 352 1.9E-40 T 28-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 CIG75_RS02125 0ffc8a1c5fb99f8cd61bf7b45d983631 492 SUPERFAMILY SSF55383 403 482 4.45E-9 T 28-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CIG75_RS02125 0ffc8a1c5fb99f8cd61bf7b45d983631 492 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 52 356 1.5E-80 T 28-03-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 CIG75_RS02125 0ffc8a1c5fb99f8cd61bf7b45d983631 492 Gene3D G3DSA:3.30.750.44 23 96 1.6E-12 T 28-03-2018 CIG75_RS02125 0ffc8a1c5fb99f8cd61bf7b45d983631 492 Gene3D G3DSA:2.30.42.10 97 177 3.4E-18 T 28-03-2018 CIG75_RS02125 0ffc8a1c5fb99f8cd61bf7b45d983631 492 SUPERFAMILY SSF52096 185 355 5.14E-58 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CIG75_RS02125 0ffc8a1c5fb99f8cd61bf7b45d983631 492 SUPERFAMILY SSF52096 29 112 5.14E-58 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CIG75_RS02125 0ffc8a1c5fb99f8cd61bf7b45d983631 492 Gene3D G3DSA:3.30.457.10 402 479 1.7E-10 T 28-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CIG75_RS02125 0ffc8a1c5fb99f8cd61bf7b45d983631 492 Pfam PF07833 Copper amine oxidase N-terminal domain 399 486 1.2E-11 T 28-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CIG75_RS02125 0ffc8a1c5fb99f8cd61bf7b45d983631 492 Pfam PF13180 PDZ domain 94 165 1.3E-11 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CIG75_RS05725 a055498aa9e1bc2cbc2a9680e83e4740 662 SUPERFAMILY SSF48208 235 647 3.71E-103 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CIG75_RS05725 a055498aa9e1bc2cbc2a9680e83e4740 662 Gene3D G3DSA:1.50.10.10 245 593 2.5E-67 T 28-03-2018 CIG75_RS05725 a055498aa9e1bc2cbc2a9680e83e4740 662 Pfam PF00723 Glycosyl hydrolases family 15 285 582 1.0E-11 T 28-03-2018 IPR011613 Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family Reactome: R-HSA-70221 CIG75_RS05725 a055498aa9e1bc2cbc2a9680e83e4740 662 Gene3D G3DSA:2.70.98.10 17 244 2.7E-52 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 CIG75_RS05725 a055498aa9e1bc2cbc2a9680e83e4740 662 Gene3D G3DSA:1.50.10.10 594 661 1.7E-11 T 28-03-2018 CIG75_RS05730 ed8d404580613dc05d9efd443c85523a 703 Pfam PF00395 S-layer homology domain 591 631 9.6E-5 T 28-03-2018 IPR001119 S-layer homology domain CIG75_RS05730 ed8d404580613dc05d9efd443c85523a 703 Pfam PF00395 S-layer homology domain 651 693 8.6E-4 T 28-03-2018 IPR001119 S-layer homology domain CIG75_RS02140 1863e232b3dd9fa8c6e0cd2b215d510d 428 SMART SM00028 189 222 2.4 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS02140 1863e232b3dd9fa8c6e0cd2b215d510d 428 SMART SM00028 347 380 11.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS02140 1863e232b3dd9fa8c6e0cd2b215d510d 428 SMART SM00028 269 302 86.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS02140 1863e232b3dd9fa8c6e0cd2b215d510d 428 SMART SM00028 147 180 55.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS02140 1863e232b3dd9fa8c6e0cd2b215d510d 428 SMART SM00028 309 342 2.3E-4 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS02140 1863e232b3dd9fa8c6e0cd2b215d510d 428 SMART SM00028 229 262 0.59 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS02140 1863e232b3dd9fa8c6e0cd2b215d510d 428 SUPERFAMILY SSF48452 72 224 1.73E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS02140 1863e232b3dd9fa8c6e0cd2b215d510d 428 Gene3D G3DSA:1.25.40.10 78 109 0.022 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS02140 1863e232b3dd9fa8c6e0cd2b215d510d 428 Pfam PF01381 Helix-turn-helix 9 61 8.5E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS02140 1863e232b3dd9fa8c6e0cd2b215d510d 428 Pfam PF13424 Tetratricopeptide repeat 190 260 1.6E-9 T 28-03-2018 CIG75_RS02140 1863e232b3dd9fa8c6e0cd2b215d510d 428 Pfam PF13424 Tetratricopeptide repeat 308 379 2.7E-12 T 28-03-2018 CIG75_RS02140 1863e232b3dd9fa8c6e0cd2b215d510d 428 Gene3D G3DSA:1.25.40.10 326 366 1.3E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS02140 1863e232b3dd9fa8c6e0cd2b215d510d 428 SUPERFAMILY SSF48452 309 413 1.08E-16 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS02140 1863e232b3dd9fa8c6e0cd2b215d510d 428 Gene3D G3DSA:3.30.70.100 290 325 1.7E-6 T 28-03-2018 CIG75_RS02140 1863e232b3dd9fa8c6e0cd2b215d510d 428 SMART SM00530 8 62 2.5E-15 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS02140 1863e232b3dd9fa8c6e0cd2b215d510d 428 Gene3D G3DSA:1.25.40.10 367 416 0.0043 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS02140 1863e232b3dd9fa8c6e0cd2b215d510d 428 SUPERFAMILY SSF47413 2 66 7.51E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CIG75_RS02140 1863e232b3dd9fa8c6e0cd2b215d510d 428 Gene3D G3DSA:1.25.40.10 203 239 5.7E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS02140 1863e232b3dd9fa8c6e0cd2b215d510d 428 Gene3D G3DSA:1.10.260.40 1 77 1.1E-18 T 28-03-2018 CIG75_RS02140 1863e232b3dd9fa8c6e0cd2b215d510d 428 SUPERFAMILY SSF48452 189 339 1.02E-21 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS02140 1863e232b3dd9fa8c6e0cd2b215d510d 428 Gene3D G3DSA:1.25.40.10 240 289 1.4E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS02140 1863e232b3dd9fa8c6e0cd2b215d510d 428 Gene3D G3DSA:1.25.40.10 110 202 4.2E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS00500 70378fb33a426877287e5a6bc10d6add 148 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 148 1.2E-44 T 28-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS00500 70378fb33a426877287e5a6bc10d6add 148 SUPERFAMILY SSF55653 57 148 5.62E-26 T 28-03-2018 IPR020069 Ribosomal protein L9, C-terminal CIG75_RS00500 70378fb33a426877287e5a6bc10d6add 148 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 46 1.6E-22 T 28-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS00500 70378fb33a426877287e5a6bc10d6add 148 Gene3D G3DSA:3.40.5.10 1 49 1.1E-22 T 28-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS00500 70378fb33a426877287e5a6bc10d6add 148 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 148 24.812 T 28-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS00500 70378fb33a426877287e5a6bc10d6add 148 Gene3D G3DSA:3.10.430.100 63 147 8.2E-29 T 28-03-2018 IPR020069 Ribosomal protein L9, C-terminal CIG75_RS00500 70378fb33a426877287e5a6bc10d6add 148 Pfam PF03948 Ribosomal protein L9, C-terminal domain 64 147 5.7E-28 T 28-03-2018 IPR020069 Ribosomal protein L9, C-terminal CIG75_RS00500 70378fb33a426877287e5a6bc10d6add 148 SUPERFAMILY SSF55658 1 56 1.27E-16 T 28-03-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal CIG75_RS00500 70378fb33a426877287e5a6bc10d6add 148 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 28-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS17670 cb74a70835f49532596099cef6b7dd24 150 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 5 136 3.6E-45 T 28-03-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 CIG75_RS17670 cb74a70835f49532596099cef6b7dd24 150 Pfam PF00583 Acetyltransferase (GNAT) family 7 116 1.8E-20 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CIG75_RS17670 cb74a70835f49532596099cef6b7dd24 150 SUPERFAMILY SSF55729 3 137 9.81E-34 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CIG75_RS17670 cb74a70835f49532596099cef6b7dd24 150 Gene3D G3DSA:3.40.630.30 1 149 1.8E-34 T 28-03-2018 CIG75_RS01860 230fe248bca176e862f30ee9b376190c 368 Pfam PF13175 AAA ATPase domain 5 54 7.7E-8 T 28-03-2018 CIG75_RS01860 230fe248bca176e862f30ee9b376190c 368 SMART SM00382 32 359 3.9E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS01860 230fe248bca176e862f30ee9b376190c 368 SUPERFAMILY SSF52540 5 347 1.29E-23 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS01860 230fe248bca176e862f30ee9b376190c 368 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 208 343 4.6E-19 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CIG75_RS01860 230fe248bca176e862f30ee9b376190c 368 Gene3D G3DSA:3.40.50.300 3 362 2.2E-28 T 28-03-2018 CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 SUPERFAMILY SSF52777 696 860 1.33E-37 T 28-03-2018 CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 SUPERFAMILY SSF52777 1769 1946 2.33E-51 T 28-03-2018 CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 SUPERFAMILY SSF56801 3234 3791 1.19E-163 T 28-03-2018 CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 SUPERFAMILY SSF47336 2724 2828 4.58E-19 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 Pfam PF00501 AMP-binding enzyme 2230 2621 5.3E-100 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 Pfam PF00501 AMP-binding enzyme 8 449 7.0E-87 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 Pfam PF00501 AMP-binding enzyme 1161 1567 3.4E-97 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 Pfam PF00501 AMP-binding enzyme 3276 3672 2.5E-101 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 SMART SM00823 Phosphopantetheine attachment site 3778 3847 4.8E-5 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 SMART SM00823 Phosphopantetheine attachment site 601 672 3.2E-15 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 SMART SM00823 Phosphopantetheine attachment site 2730 2799 6.7E-8 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 SMART SM00823 Phosphopantetheine attachment site 1677 1746 6.1E-4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1701 1716 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 SUPERFAMILY SSF47336 599 678 2.88E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 Gene3D G3DSA:1.10.1200.10 3785 3829 6.1E-19 T 28-03-2018 CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 Gene3D G3DSA:3.40.50.980 3266 3421 1.8E-50 T 28-03-2018 CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 Gene3D G3DSA:3.40.50.980 1 166 4.3E-36 T 28-03-2018 CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 Gene3D G3DSA:3.40.50.980 2222 2379 3.8E-48 T 28-03-2018 CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 Gene3D G3DSA:3.40.50.980 1152 1308 2.6E-48 T 28-03-2018 CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 Gene3D G3DSA:3.40.50.980 3422 3571 1.2E-32 T 28-03-2018 CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 Gene3D G3DSA:3.40.50.980 167 337 8.6E-36 T 28-03-2018 CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 Gene3D G3DSA:3.40.50.980 1309 1471 4.7E-34 T 28-03-2018 CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 Gene3D G3DSA:3.40.50.980 2380 2530 1.2E-28 T 28-03-2018 CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2251 2645 3.1E-138 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 3295 3696 8.1E-133 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1182 1591 4.2E-128 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 SUPERFAMILY SSF52777 2818 2991 1.67E-51 T 28-03-2018 CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 Gene3D G3DSA:2.30.38.10 364 441 8.6E-19 T 28-03-2018 CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3802 3817 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 Pfam PF13193 AMP-binding enzyme C-terminal domain 2629 2704 5.8E-14 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 Pfam PF13193 AMP-binding enzyme C-terminal domain 1575 1650 1.9E-13 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 Pfam PF13193 AMP-binding enzyme C-terminal domain 3680 3750 4.6E-11 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 SUPERFAMILY SSF47336 3770 3844 4.84E-19 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 Gene3D G3DSA:3.30.300.30 442 550 1.6E-15 T 28-03-2018 CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2374 2385 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 Gene3D G3DSA:2.30.38.10 3572 3664 7.6E-25 T 28-03-2018 CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 Gene3D G3DSA:1.10.1200.10 595 686 7.1E-14 T 28-03-2018 CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 SUPERFAMILY SSF52777 871 1129 1.67E-56 T 28-03-2018 CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 SUPERFAMILY SSF47336 1669 1742 2.62E-20 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 SUPERFAMILY SSF56801 2191 2742 9.16E-161 T 28-03-2018 CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 Gene3D G3DSA:2.30.38.10 2531 2611 8.3E-25 T 28-03-2018 CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 Gene3D G3DSA:2.30.38.10 1475 1557 8.2E-23 T 28-03-2018 CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 Gene3D G3DSA:3.30.559.10 2798 3013 2.2E-49 T 28-03-2018 CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 Gene3D G3DSA:3.30.559.10 3830 4073 3.6E-41 T 28-03-2018 CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 Gene3D G3DSA:3.30.559.10 1748 1968 5.5E-49 T 28-03-2018 CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 SUPERFAMILY SSF52777 4054 4288 2.33E-53 T 28-03-2018 CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 Gene3D G3DSA:1.10.1200.10 2736 2797 7.8E-23 T 28-03-2018 CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 Gene3D G3DSA:1.10.1200.10 1683 1746 5.0E-23 T 28-03-2018 CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 Gene3D G3DSA:3.30.559.10 687 863 8.6E-31 T 28-03-2018 CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 SUPERFAMILY SSF52777 2999 3261 1.1E-69 T 28-03-2018 CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2754 2769 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 ProSitePatterns PS00455 Putative AMP-binding domain signature. 3416 3427 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 SUPERFAMILY SSF56801 1121 1690 3.27E-167 T 28-03-2018 CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 Gene3D G3DSA:3.30.300.30 2616 2735 3.8E-39 T 28-03-2018 CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 Gene3D G3DSA:3.30.300.30 1562 1682 7.2E-41 T 28-03-2018 CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 Gene3D G3DSA:3.30.300.30 3667 3784 1.7E-37 T 28-03-2018 CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 Pfam PF00550 Phosphopantetheine attachment site 603 667 3.9E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 Pfam PF00550 Phosphopantetheine attachment site 1678 1740 5.4E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 Pfam PF00550 Phosphopantetheine attachment site 3779 3842 4.5E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 Pfam PF00550 Phosphopantetheine attachment site 2732 2794 1.8E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 SUPERFAMILY SSF56801 2 553 1.1E-112 T 28-03-2018 CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 ProSitePatterns PS00455 Putative AMP-binding domain signature. 161 172 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 SUPERFAMILY SSF52777 1955 2212 1.11E-69 T 28-03-2018 CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1303 1314 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 Pfam PF00668 Condensation domain 1766 2211 3.6E-122 T 28-03-2018 IPR001242 Condensation domain CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 Pfam PF00668 Condensation domain 2816 3255 8.1E-119 T 28-03-2018 IPR001242 Condensation domain CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 Pfam PF00668 Condensation domain 689 1140 9.0E-93 T 28-03-2018 IPR001242 Condensation domain CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 Pfam PF00668 Condensation domain 3871 4295 6.2E-99 T 28-03-2018 IPR001242 Condensation domain CIG75_RS10705 685eb962daf7d1aa5f33d4c636f2fcb2 4296 SUPERFAMILY SSF52777 3872 4046 1.89E-49 T 28-03-2018 CIG75_RS15845 18e609fd61c2cfe8e858a55a340701ea 223 PIRSF PIRSF018957 28 217 9.0E-49 T 28-03-2018 IPR008307 Uncharacterised conserved protein UCP018957 CIG75_RS15845 18e609fd61c2cfe8e858a55a340701ea 223 Pfam PF08819 Domain of unknown function (DUF1802) 35 211 2.1E-56 T 28-03-2018 IPR014923 Protein of unknown function DUF1802 CIG75_RS08345 5706037e15a1b612df0cb044587df49f 239 Pfam PF02597 ThiS family 5 81 1.9E-13 T 28-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 CIG75_RS08345 5706037e15a1b612df0cb044587df49f 239 Gene3D G3DSA:3.10.20.30 3 81 4.9E-18 T 28-03-2018 IPR012675 Beta-grasp domain CIG75_RS08345 5706037e15a1b612df0cb044587df49f 239 SUPERFAMILY SSF54285 1 79 1.18E-15 T 28-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp CIG75_RS08345 5706037e15a1b612df0cb044587df49f 239 SUPERFAMILY SSF54690 90 228 9.94E-45 T 28-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CIG75_RS08345 5706037e15a1b612df0cb044587df49f 239 Gene3D G3DSA:3.90.1170.40 87 233 5.5E-48 T 28-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CIG75_RS08345 5706037e15a1b612df0cb044587df49f 239 Pfam PF02391 MoaE protein 93 204 3.4E-36 T 28-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CIG75_RS01435 1bda1656c08aabee2d2a894f409a5617 276 Pfam PF01564 Spermine/spermidine synthase domain 58 236 9.8E-61 T 28-03-2018 CIG75_RS01435 1bda1656c08aabee2d2a894f409a5617 276 Gene3D G3DSA:2.30.140.10 4 51 2.4E-19 T 28-03-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 CIG75_RS01435 1bda1656c08aabee2d2a894f409a5617 276 Pfam PF17284 Spermidine synthase tetramerisation domain 3 54 7.3E-18 T 28-03-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 CIG75_RS01435 1bda1656c08aabee2d2a894f409a5617 276 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 3 276 40.509 T 28-03-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 CIG75_RS01435 1bda1656c08aabee2d2a894f409a5617 276 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 79 92 - T 28-03-2018 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 CIG75_RS01435 1bda1656c08aabee2d2a894f409a5617 276 TIGRFAM TIGR00417 speE: spermidine synthase 4 270 1.2E-109 T 28-03-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 CIG75_RS01435 1bda1656c08aabee2d2a894f409a5617 276 SUPERFAMILY SSF53335 3 275 1.49E-82 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CIG75_RS01435 1bda1656c08aabee2d2a894f409a5617 276 Gene3D G3DSA:3.40.50.150 55 276 1.3E-40 T 28-03-2018 CIG75_RS17045 717d5acafc57479185ce523f6b212374 789 SUPERFAMILY SSF50249 631 711 4.86E-22 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CIG75_RS17045 717d5acafc57479185ce523f6b212374 789 SMART SM00955 248 582 5.4E-176 T 28-03-2018 CIG75_RS17045 717d5acafc57479185ce523f6b212374 789 TIGRFAM TIGR02063 RNase_R: ribonuclease R 4 713 1.4E-272 T 28-03-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 CIG75_RS17045 717d5acafc57479185ce523f6b212374 789 SUPERFAMILY SSF50249 175 489 6.86E-145 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CIG75_RS17045 717d5acafc57479185ce523f6b212374 789 SUPERFAMILY SSF50249 528 631 6.86E-145 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CIG75_RS17045 717d5acafc57479185ce523f6b212374 789 Gene3D G3DSA:2.40.50.140 630 714 8.5E-22 T 28-03-2018 CIG75_RS17045 717d5acafc57479185ce523f6b212374 789 Pfam PF00575 S1 RNA binding domain 630 711 4.1E-14 T 28-03-2018 IPR003029 S1 domain GO:0003676 CIG75_RS17045 717d5acafc57479185ce523f6b212374 789 Pfam PF00773 RNB domain 248 581 2.7E-110 T 28-03-2018 CIG75_RS17045 717d5acafc57479185ce523f6b212374 789 Pfam PF08206 Ribonuclease B OB domain 71 131 1.1E-18 T 28-03-2018 IPR013223 Ribonuclease B, N-terminal OB domain CIG75_RS17045 717d5acafc57479185ce523f6b212374 789 Pfam PF08206 Ribonuclease B OB domain 148 201 1.3E-5 T 28-03-2018 IPR013223 Ribonuclease B, N-terminal OB domain CIG75_RS17045 717d5acafc57479185ce523f6b212374 789 SUPERFAMILY SSF50249 51 134 1.2E-18 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CIG75_RS17045 717d5acafc57479185ce523f6b212374 789 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 52 713 2.6E-221 T 28-03-2018 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 CIG75_RS17045 717d5acafc57479185ce523f6b212374 789 Gene3D G3DSA:2.40.50.140 69 283 0.0023 T 28-03-2018 CIG75_RS17045 717d5acafc57479185ce523f6b212374 789 Gene3D G3DSA:1.10.10.10 3 60 2.6E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS17045 717d5acafc57479185ce523f6b212374 789 ProSitePatterns PS01175 Ribonuclease II family signature. 549 573 - T 28-03-2018 IPR022966 Ribonuclease II/R, conserved site CIG75_RS17045 717d5acafc57479185ce523f6b212374 789 Hamap MF_01895 Ribonuclease R [rnr]. 22 713 60.017 T 28-03-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 CIG75_RS17045 717d5acafc57479185ce523f6b212374 789 SMART SM00316 631 713 6.1E-16 T 28-03-2018 IPR022967 RNA-binding domain, S1 CIG75_RS17045 717d5acafc57479185ce523f6b212374 789 SMART SM00357 70 132 1.2E-12 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 CIG75_RS17045 717d5acafc57479185ce523f6b212374 789 SMART SM00357 140 202 3.7E-6 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 CIG75_RS09500 0e9f01c5ad608b2db4d4d778fba8e69f 427 Gene3D G3DSA:1.25.40.10 73 186 7.4E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS09500 0e9f01c5ad608b2db4d4d778fba8e69f 427 Gene3D G3DSA:1.10.260.40 1 72 3.9E-16 T 28-03-2018 CIG75_RS09500 0e9f01c5ad608b2db4d4d778fba8e69f 427 SUPERFAMILY SSF48452 66 225 7.59E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS09500 0e9f01c5ad608b2db4d4d778fba8e69f 427 SMART SM00530 7 61 7.0E-14 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS09500 0e9f01c5ad608b2db4d4d778fba8e69f 427 Gene3D G3DSA:1.25.40.10 189 237 5.4E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS09500 0e9f01c5ad608b2db4d4d778fba8e69f 427 Gene3D G3DSA:3.30.70.100 238 274 0.11 T 28-03-2018 CIG75_RS09500 0e9f01c5ad608b2db4d4d778fba8e69f 427 Gene3D G3DSA:1.25.40.10 275 415 5.7E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS09500 0e9f01c5ad608b2db4d4d778fba8e69f 427 Pfam PF13424 Tetratricopeptide repeat 190 255 2.6E-7 T 28-03-2018 CIG75_RS09500 0e9f01c5ad608b2db4d4d778fba8e69f 427 SMART SM00028 346 379 120.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS09500 0e9f01c5ad608b2db4d4d778fba8e69f 427 SMART SM00028 308 341 100.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS09500 0e9f01c5ad608b2db4d4d778fba8e69f 427 SMART SM00028 148 181 160.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS09500 0e9f01c5ad608b2db4d4d778fba8e69f 427 SMART SM00028 190 223 1.5 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS09500 0e9f01c5ad608b2db4d4d778fba8e69f 427 SMART SM00028 228 261 3.6 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS09500 0e9f01c5ad608b2db4d4d778fba8e69f 427 Pfam PF01381 Helix-turn-helix 8 60 2.8E-11 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS09500 0e9f01c5ad608b2db4d4d778fba8e69f 427 SUPERFAMILY SSF48452 228 411 8.34E-15 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS09500 0e9f01c5ad608b2db4d4d778fba8e69f 427 SUPERFAMILY SSF47413 3 62 1.38E-14 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CIG75_RS06350 df6e80ef2447226649ce19a799ee75ae 373 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 6 372 2.6E-178 T 28-03-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CIG75_RS06350 df6e80ef2447226649ce19a799ee75ae 373 Gene3D G3DSA:3.20.20.105 1 372 1.8E-163 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CIG75_RS06350 df6e80ef2447226649ce19a799ee75ae 373 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 6 371 7.7E-169 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CIG75_RS06350 df6e80ef2447226649ce19a799ee75ae 373 Pfam PF01702 Queuine tRNA-ribosyltransferase 132 365 4.5E-92 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CIG75_RS06350 df6e80ef2447226649ce19a799ee75ae 373 SUPERFAMILY SSF51713 2 369 1.57E-164 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CIG75_RS06350 df6e80ef2447226649ce19a799ee75ae 373 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 4 368 58.291 T 28-03-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CIG75_RS11050 eba61fc2c41b86cd2eddeefeccfcdbac 1343 Gene3D G3DSA:1.10.1200.10 1023 1087 1.3E-18 T 28-03-2018 CIG75_RS11050 eba61fc2c41b86cd2eddeefeccfcdbac 1343 Gene3D G3DSA:3.40.50.1820 1088 1340 1.2E-22 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS11050 eba61fc2c41b86cd2eddeefeccfcdbac 1343 Pfam PF00975 Thioesterase domain 1104 1329 2.5E-33 T 28-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CIG75_RS11050 eba61fc2c41b86cd2eddeefeccfcdbac 1343 ProSitePatterns PS00455 Putative AMP-binding domain signature. 651 662 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS11050 eba61fc2c41b86cd2eddeefeccfcdbac 1343 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 523 930 1.0E-126 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS11050 eba61fc2c41b86cd2eddeefeccfcdbac 1343 SMART SM00823 Phosphopantetheine attachment site 1017 1086 0.005 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS11050 eba61fc2c41b86cd2eddeefeccfcdbac 1343 Gene3D G3DSA:3.30.559.10 29 242 2.2E-45 T 28-03-2018 CIG75_RS11050 eba61fc2c41b86cd2eddeefeccfcdbac 1343 Pfam PF00501 AMP-binding enzyme 502 906 3.6E-95 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS11050 eba61fc2c41b86cd2eddeefeccfcdbac 1343 Gene3D G3DSA:3.40.50.980 493 657 2.4E-49 T 28-03-2018 CIG75_RS11050 eba61fc2c41b86cd2eddeefeccfcdbac 1343 Pfam PF13193 AMP-binding enzyme C-terminal domain 914 989 5.9E-11 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS11050 eba61fc2c41b86cd2eddeefeccfcdbac 1343 SUPERFAMILY SSF53474 1083 1338 8.83E-59 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS11050 eba61fc2c41b86cd2eddeefeccfcdbac 1343 Pfam PF00668 Condensation domain 46 481 1.6E-121 T 28-03-2018 IPR001242 Condensation domain CIG75_RS11050 eba61fc2c41b86cd2eddeefeccfcdbac 1343 Gene3D G3DSA:2.30.38.10 812 898 6.1E-24 T 28-03-2018 CIG75_RS11050 eba61fc2c41b86cd2eddeefeccfcdbac 1343 Gene3D G3DSA:3.40.50.980 658 811 1.6E-27 T 28-03-2018 CIG75_RS11050 eba61fc2c41b86cd2eddeefeccfcdbac 1343 PIRSF PIRSF001617 225 874 6.6E-34 T 28-03-2018 CIG75_RS11050 eba61fc2c41b86cd2eddeefeccfcdbac 1343 PIRSF PIRSF001617 870 959 1.3E-14 T 28-03-2018 CIG75_RS11050 eba61fc2c41b86cd2eddeefeccfcdbac 1343 PIRSF PIRSF001617 953 1091 2.5E-21 T 28-03-2018 CIG75_RS11050 eba61fc2c41b86cd2eddeefeccfcdbac 1343 Gene3D G3DSA:3.30.300.30 901 1022 3.9E-38 T 28-03-2018 CIG75_RS11050 eba61fc2c41b86cd2eddeefeccfcdbac 1343 SUPERFAMILY SSF52777 225 470 3.78E-66 T 28-03-2018 CIG75_RS11050 eba61fc2c41b86cd2eddeefeccfcdbac 1343 Pfam PF00550 Phosphopantetheine attachment site 1019 1082 1.3E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS11050 eba61fc2c41b86cd2eddeefeccfcdbac 1343 SUPERFAMILY SSF52777 49 219 1.07E-52 T 28-03-2018 CIG75_RS11050 eba61fc2c41b86cd2eddeefeccfcdbac 1343 SUPERFAMILY SSF47336 1010 1083 5.76E-18 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS11050 eba61fc2c41b86cd2eddeefeccfcdbac 1343 SUPERFAMILY SSF56801 459 1030 2.49E-154 T 28-03-2018 CIG75_RS11255 925cdae97254e0325b410d18c1b2c1be 582 Pfam PF17482 Phage tail sheath C-terminal domain 471 577 2.5E-15 T 28-03-2018 IPR020287 Tail sheath protein, C-terminal domain CIG75_RS11255 925cdae97254e0325b410d18c1b2c1be 582 Pfam PF04984 Phage tail sheath protein subtilisin-like domain 314 469 2.6E-25 T 28-03-2018 IPR035089 Tail sheath protein, subtilisin-like domain CIG75_RS14515 b6217f137a76e6e7dc139fd7038614c2 425 PIRSF PIRSF001529 1 425 4.2E-143 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CIG75_RS14515 b6217f137a76e6e7dc139fd7038614c2 425 Gene3D G3DSA:1.10.287.40 2 106 1.5E-21 T 28-03-2018 CIG75_RS14515 b6217f137a76e6e7dc139fd7038614c2 425 Gene3D G3DSA:3.30.930.10 107 425 3.0E-77 T 28-03-2018 CIG75_RS14515 b6217f137a76e6e7dc139fd7038614c2 425 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 416 4.6E-137 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CIG75_RS14515 b6217f137a76e6e7dc139fd7038614c2 425 SUPERFAMILY SSF46589 1 114 3.56E-24 T 28-03-2018 IPR010978 tRNA-binding arm GO:0000166 CIG75_RS14515 b6217f137a76e6e7dc139fd7038614c2 425 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 222 399 2.7E-24 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CIG75_RS14515 b6217f137a76e6e7dc139fd7038614c2 425 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 421 36.264 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CIG75_RS14515 b6217f137a76e6e7dc139fd7038614c2 425 PRINTS PR00981 Seryl-tRNA synthetase signature 333 349 2.5E-28 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CIG75_RS14515 b6217f137a76e6e7dc139fd7038614c2 425 PRINTS PR00981 Seryl-tRNA synthetase signature 316 329 2.5E-28 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CIG75_RS14515 b6217f137a76e6e7dc139fd7038614c2 425 PRINTS PR00981 Seryl-tRNA synthetase signature 262 274 2.5E-28 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CIG75_RS14515 b6217f137a76e6e7dc139fd7038614c2 425 PRINTS PR00981 Seryl-tRNA synthetase signature 351 367 2.5E-28 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CIG75_RS14515 b6217f137a76e6e7dc139fd7038614c2 425 PRINTS PR00981 Seryl-tRNA synthetase signature 274 287 2.5E-28 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CIG75_RS14515 b6217f137a76e6e7dc139fd7038614c2 425 SUPERFAMILY SSF55681 119 419 4.48E-80 T 28-03-2018 CIG75_RS14515 b6217f137a76e6e7dc139fd7038614c2 425 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 108 2.8E-22 T 28-03-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 CIG75_RS00270 25b34ed4c5e2bef531290984068ea5cd 252 Pfam PF13614 AAA domain 3 178 1.9E-72 T 28-03-2018 IPR025669 AAA domain CIG75_RS00270 25b34ed4c5e2bef531290984068ea5cd 252 PRINTS PR00091 Nitrogenase component II signature 31 46 9.3E-5 T 28-03-2018 CIG75_RS00270 25b34ed4c5e2bef531290984068ea5cd 252 PRINTS PR00091 Nitrogenase component II signature 9 22 9.3E-5 T 28-03-2018 CIG75_RS00270 25b34ed4c5e2bef531290984068ea5cd 252 PIRSF PIRSF009320 2 50 5.2E-16 T 28-03-2018 CIG75_RS00270 25b34ed4c5e2bef531290984068ea5cd 252 PIRSF PIRSF009320 91 251 3.4E-8 T 28-03-2018 CIG75_RS00270 25b34ed4c5e2bef531290984068ea5cd 252 Gene3D G3DSA:3.40.50.300 1 251 6.3E-66 T 28-03-2018 CIG75_RS00270 25b34ed4c5e2bef531290984068ea5cd 252 SUPERFAMILY SSF52540 1 251 1.01E-72 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS03100 acb6cc039eb34370cf9971499fae4d55 2129 SUPERFAMILY SSF47336 970 1043 8.9E-19 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS03100 acb6cc039eb34370cf9971499fae4d55 2129 SUPERFAMILY SSF52777 17 193 4.78E-50 T 28-03-2018 CIG75_RS03100 acb6cc039eb34370cf9971499fae4d55 2129 SUPERFAMILY SSF52777 1070 1246 1.56E-46 T 28-03-2018 CIG75_RS03100 acb6cc039eb34370cf9971499fae4d55 2129 Gene3D G3DSA:3.30.300.30 863 983 1.2E-44 T 28-03-2018 CIG75_RS03100 acb6cc039eb34370cf9971499fae4d55 2129 Gene3D G3DSA:3.30.300.30 1914 2035 1.3E-43 T 28-03-2018 CIG75_RS03100 acb6cc039eb34370cf9971499fae4d55 2129 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2054 2069 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS03100 acb6cc039eb34370cf9971499fae4d55 2129 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1002 1017 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS03100 acb6cc039eb34370cf9971499fae4d55 2129 SUPERFAMILY SSF47336 2023 2096 1.96E-19 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS03100 acb6cc039eb34370cf9971499fae4d55 2129 Pfam PF13193 AMP-binding enzyme C-terminal domain 1927 2002 7.5E-16 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS03100 acb6cc039eb34370cf9971499fae4d55 2129 Pfam PF13193 AMP-binding enzyme C-terminal domain 876 951 1.1E-15 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS03100 acb6cc039eb34370cf9971499fae4d55 2129 SUPERFAMILY SSF52777 201 464 5.11E-66 T 28-03-2018 CIG75_RS03100 acb6cc039eb34370cf9971499fae4d55 2129 Pfam PF00501 AMP-binding enzyme 478 868 3.3E-98 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS03100 acb6cc039eb34370cf9971499fae4d55 2129 Pfam PF00501 AMP-binding enzyme 1531 1919 5.1E-100 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS03100 acb6cc039eb34370cf9971499fae4d55 2129 SUPERFAMILY SSF56801 436 991 2.09E-161 T 28-03-2018 CIG75_RS03100 acb6cc039eb34370cf9971499fae4d55 2129 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1551 1943 5.0E-131 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS03100 acb6cc039eb34370cf9971499fae4d55 2129 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 499 892 4.2E-131 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS03100 acb6cc039eb34370cf9971499fae4d55 2129 Pfam PF00668 Condensation domain 1069 1511 4.5E-110 T 28-03-2018 IPR001242 Condensation domain CIG75_RS03100 acb6cc039eb34370cf9971499fae4d55 2129 Pfam PF00668 Condensation domain 14 458 2.5E-116 T 28-03-2018 IPR001242 Condensation domain CIG75_RS03100 acb6cc039eb34370cf9971499fae4d55 2129 Gene3D G3DSA:1.10.1200.10 984 1053 1.8E-21 T 28-03-2018 CIG75_RS03100 acb6cc039eb34370cf9971499fae4d55 2129 Gene3D G3DSA:1.10.1200.10 2036 2112 5.9E-23 T 28-03-2018 CIG75_RS03100 acb6cc039eb34370cf9971499fae4d55 2129 SUPERFAMILY SSF56801 1488 2043 4.71E-162 T 28-03-2018 CIG75_RS03100 acb6cc039eb34370cf9971499fae4d55 2129 Gene3D G3DSA:3.40.50.980 626 777 3.4E-28 T 28-03-2018 CIG75_RS03100 acb6cc039eb34370cf9971499fae4d55 2129 Gene3D G3DSA:3.40.50.980 1678 1829 2.3E-26 T 28-03-2018 CIG75_RS03100 acb6cc039eb34370cf9971499fae4d55 2129 Gene3D G3DSA:3.30.559.10 1054 1269 2.7E-42 T 28-03-2018 CIG75_RS03100 acb6cc039eb34370cf9971499fae4d55 2129 Gene3D G3DSA:3.30.559.10 1 219 9.3E-45 T 28-03-2018 CIG75_RS03100 acb6cc039eb34370cf9971499fae4d55 2129 SMART SM00823 Phosphopantetheine attachment site 978 1047 0.075 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS03100 acb6cc039eb34370cf9971499fae4d55 2129 SMART SM00823 Phosphopantetheine attachment site 2030 2099 0.0018 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS03100 acb6cc039eb34370cf9971499fae4d55 2129 Gene3D G3DSA:2.30.38.10 1830 1912 1.6E-24 T 28-03-2018 CIG75_RS03100 acb6cc039eb34370cf9971499fae4d55 2129 Gene3D G3DSA:2.30.38.10 779 861 1.7E-24 T 28-03-2018 CIG75_RS03100 acb6cc039eb34370cf9971499fae4d55 2129 Pfam PF00550 Phosphopantetheine attachment site 980 1043 4.9E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS03100 acb6cc039eb34370cf9971499fae4d55 2129 Pfam PF00550 Phosphopantetheine attachment site 2032 2095 7.9E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS03100 acb6cc039eb34370cf9971499fae4d55 2129 SUPERFAMILY SSF52777 1255 1517 2.11E-70 T 28-03-2018 CIG75_RS03100 acb6cc039eb34370cf9971499fae4d55 2129 Gene3D G3DSA:3.40.50.980 1522 1677 1.1E-49 T 28-03-2018 CIG75_RS03100 acb6cc039eb34370cf9971499fae4d55 2129 Gene3D G3DSA:3.40.50.980 469 625 9.0E-50 T 28-03-2018 CIG75_RS03100 acb6cc039eb34370cf9971499fae4d55 2129 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1672 1683 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS03100 acb6cc039eb34370cf9971499fae4d55 2129 ProSitePatterns PS00455 Putative AMP-binding domain signature. 620 631 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS00790 538949cb8dd14240a080209c93f88235 279 SUPERFAMILY SSF51430 7 273 2.88E-93 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CIG75_RS00790 538949cb8dd14240a080209c93f88235 279 Gene3D G3DSA:3.20.20.100 1 278 1.6E-98 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CIG75_RS00790 538949cb8dd14240a080209c93f88235 279 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 233 248 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CIG75_RS00790 538949cb8dd14240a080209c93f88235 279 PIRSF PIRSF000097 119 276 7.2E-54 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CIG75_RS00790 538949cb8dd14240a080209c93f88235 279 PIRSF PIRSF000097 1 124 7.8E-42 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CIG75_RS00790 538949cb8dd14240a080209c93f88235 279 PRINTS PR00069 Aldo-keto reductase signature 129 146 1.8E-50 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CIG75_RS00790 538949cb8dd14240a080209c93f88235 279 PRINTS PR00069 Aldo-keto reductase signature 39 63 1.8E-50 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CIG75_RS00790 538949cb8dd14240a080209c93f88235 279 PRINTS PR00069 Aldo-keto reductase signature 200 224 1.8E-50 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CIG75_RS00790 538949cb8dd14240a080209c93f88235 279 PRINTS PR00069 Aldo-keto reductase signature 99 117 1.8E-50 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CIG75_RS00790 538949cb8dd14240a080209c93f88235 279 PRINTS PR00069 Aldo-keto reductase signature 163 192 1.8E-50 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CIG75_RS00790 538949cb8dd14240a080209c93f88235 279 Pfam PF00248 Aldo/keto reductase family 30 265 2.1E-48 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CIG75_RS00790 538949cb8dd14240a080209c93f88235 279 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 43 60 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CIG75_RS00790 538949cb8dd14240a080209c93f88235 279 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 129 146 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CIG75_RS12110 dc2c4e0d6bf71b305edbca9ef35dc332 702 SUPERFAMILY SSF56712 4 590 1.44E-197 T 28-03-2018 IPR023405 DNA topoisomerase, type IA, core domain CIG75_RS12110 dc2c4e0d6bf71b305edbca9ef35dc332 702 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 659 686 0.0057 T 28-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 CIG75_RS12110 dc2c4e0d6bf71b305edbca9ef35dc332 702 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 618 656 3.2E-12 T 28-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 CIG75_RS12110 dc2c4e0d6bf71b305edbca9ef35dc332 702 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 579 614 2.0E-13 T 28-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 CIG75_RS12110 dc2c4e0d6bf71b305edbca9ef35dc332 702 Pfam PF01131 DNA topoisomerase 128 548 2.2E-131 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CIG75_RS12110 dc2c4e0d6bf71b305edbca9ef35dc332 702 Gene3D G3DSA:3.30.65.10 616 655 4.6E-9 T 28-03-2018 CIG75_RS12110 dc2c4e0d6bf71b305edbca9ef35dc332 702 Gene3D G3DSA:3.30.65.10 656 701 2.5E-5 T 28-03-2018 CIG75_RS12110 dc2c4e0d6bf71b305edbca9ef35dc332 702 Gene3D G3DSA:3.30.65.10 566 615 4.2E-17 T 28-03-2018 CIG75_RS12110 dc2c4e0d6bf71b305edbca9ef35dc332 702 Gene3D G3DSA:3.40.50.140 2 129 3.2E-37 T 28-03-2018 CIG75_RS12110 dc2c4e0d6bf71b305edbca9ef35dc332 702 Pfam PF01751 Toprim domain 5 113 1.0E-27 T 28-03-2018 IPR006171 TOPRIM domain CIG75_RS12110 dc2c4e0d6bf71b305edbca9ef35dc332 702 Gene3D G3DSA:1.10.460.10 453 565 3.7E-27 T 28-03-2018 CIG75_RS12110 dc2c4e0d6bf71b305edbca9ef35dc332 702 Gene3D G3DSA:1.10.460.10 135 322 2.1E-46 T 28-03-2018 CIG75_RS12110 dc2c4e0d6bf71b305edbca9ef35dc332 702 Hamap MF_00952 DNA topoisomerase 1 [topA]. 3 634 53.868 T 28-03-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 CIG75_RS12110 dc2c4e0d6bf71b305edbca9ef35dc332 702 Gene3D G3DSA:2.70.20.10 325 452 3.0E-43 T 28-03-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 CIG75_RS12110 dc2c4e0d6bf71b305edbca9ef35dc332 702 SMART SM00437 242 511 3.0E-115 T 28-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 CIG75_RS12110 dc2c4e0d6bf71b305edbca9ef35dc332 702 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 5 612 3.6E-255 T 28-03-2018 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 CIG75_RS12110 dc2c4e0d6bf71b305edbca9ef35dc332 702 SMART SM00493 3 103 4.6E-30 T 28-03-2018 IPR006171 TOPRIM domain CIG75_RS12110 dc2c4e0d6bf71b305edbca9ef35dc332 702 SUPERFAMILY SSF57783 574 614 4.42E-14 T 28-03-2018 CIG75_RS12110 dc2c4e0d6bf71b305edbca9ef35dc332 702 SMART SM00436 104 192 8.2E-50 T 28-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 CIG75_RS12110 dc2c4e0d6bf71b305edbca9ef35dc332 702 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 162 180 3.0E-35 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CIG75_RS12110 dc2c4e0d6bf71b305edbca9ef35dc332 702 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 293 302 3.0E-35 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CIG75_RS12110 dc2c4e0d6bf71b305edbca9ef35dc332 702 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 371 387 3.0E-35 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CIG75_RS12110 dc2c4e0d6bf71b305edbca9ef35dc332 702 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 474 488 3.0E-35 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CIG75_RS12110 dc2c4e0d6bf71b305edbca9ef35dc332 702 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 77 90 3.0E-35 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CIG75_RS12110 dc2c4e0d6bf71b305edbca9ef35dc332 702 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 279 302 - T 28-03-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 CIG75_RS09865 a8195a6296c0d80a1b6b7ff43506734a 214 SUPERFAMILY SSF52540 1 198 8.32E-19 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS09865 a8195a6296c0d80a1b6b7ff43506734a 214 Gene3D G3DSA:3.40.50.300 1 213 4.9E-20 T 28-03-2018 CIG75_RS11285 fa7bbb0a0877bd51444d4953a95069e1 360 Pfam PF08402 TOBE domain 262 328 1.5E-7 T 28-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CIG75_RS11285 fa7bbb0a0877bd51444d4953a95069e1 360 SUPERFAMILY SSF52540 3 235 5.19E-82 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS11285 fa7bbb0a0877bd51444d4953a95069e1 360 Pfam PF00005 ABC transporter 19 161 1.1E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS11285 fa7bbb0a0877bd51444d4953a95069e1 360 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS11285 fa7bbb0a0877bd51444d4953a95069e1 360 Gene3D G3DSA:3.40.50.300 2 289 9.9E-73 T 28-03-2018 CIG75_RS11285 fa7bbb0a0877bd51444d4953a95069e1 360 SUPERFAMILY SSF50331 249 335 2.04E-9 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CIG75_RS11285 fa7bbb0a0877bd51444d4953a95069e1 360 TIGRFAM TIGR00968 3a0106s01: sulfate ABC transporter, ATP-binding protein 3 236 8.2E-106 T 28-03-2018 IPR005666 Sulphate transport system permease protein 1 GO:0006810|GO:0016020|GO:0042626 KEGG: 00920+3.6.3.25 CIG75_RS11285 fa7bbb0a0877bd51444d4953a95069e1 360 SMART SM00382 27 210 4.6E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS10570 07b17ddbf3c9db887e3a44a7e7917ea6 85 Pfam PF00072 Response regulator receiver domain 5 61 1.1E-12 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CIG75_RS10570 07b17ddbf3c9db887e3a44a7e7917ea6 85 Gene3D G3DSA:3.40.50.2300 1 71 9.7E-16 T 28-03-2018 CIG75_RS10570 07b17ddbf3c9db887e3a44a7e7917ea6 85 SUPERFAMILY SSF52172 3 61 9.53E-17 T 28-03-2018 IPR011006 CheY-like superfamily CIG75_RS18460 571279dd0f1cf5bb4c539dba23246bb2 438 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 407 424 - T 28-03-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS18460 571279dd0f1cf5bb4c539dba23246bb2 438 SUPERFAMILY SSF53697 9 436 8.46E-119 T 28-03-2018 CIG75_RS18460 571279dd0f1cf5bb4c539dba23246bb2 438 Gene3D G3DSA:3.40.50.10490 51 223 8.1E-49 T 28-03-2018 CIG75_RS18460 571279dd0f1cf5bb4c539dba23246bb2 438 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 201 214 - T 28-03-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS18460 571279dd0f1cf5bb4c539dba23246bb2 438 PRINTS PR00662 Glucose-6-phosphate isomerase signature 375 393 2.5E-20 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS18460 571279dd0f1cf5bb4c539dba23246bb2 438 PRINTS PR00662 Glucose-6-phosphate isomerase signature 272 293 2.5E-20 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS18460 571279dd0f1cf5bb4c539dba23246bb2 438 PRINTS PR00662 Glucose-6-phosphate isomerase signature 393 407 2.5E-20 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS18460 571279dd0f1cf5bb4c539dba23246bb2 438 PRINTS PR00662 Glucose-6-phosphate isomerase signature 75 94 2.5E-20 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS18460 571279dd0f1cf5bb4c539dba23246bb2 438 PRINTS PR00662 Glucose-6-phosphate isomerase signature 197 215 2.5E-20 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS18460 571279dd0f1cf5bb4c539dba23246bb2 438 PRINTS PR00662 Glucose-6-phosphate isomerase signature 407 420 2.5E-20 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS18460 571279dd0f1cf5bb4c539dba23246bb2 438 Pfam PF00342 Phosphoglucose isomerase 75 294 7.2E-16 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS18460 571279dd0f1cf5bb4c539dba23246bb2 438 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 1 434 22.788 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS18460 571279dd0f1cf5bb4c539dba23246bb2 438 Gene3D G3DSA:3.40.50.10490 1 50 0.018 T 28-03-2018 CIG75_RS18460 571279dd0f1cf5bb4c539dba23246bb2 438 Gene3D G3DSA:3.40.50.10490 224 416 3.0E-50 T 28-03-2018 CIG75_RS00635 a204710de2665cdbeb5a57ead7a92fd1 266 SUPERFAMILY SSF52540 6 262 1.72E-24 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS00635 a204710de2665cdbeb5a57ead7a92fd1 266 Pfam PF13401 AAA domain 42 170 4.6E-21 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS00635 a204710de2665cdbeb5a57ead7a92fd1 266 Gene3D G3DSA:3.40.50.300 23 192 8.0E-11 T 28-03-2018 CIG75_RS14215 a204710de2665cdbeb5a57ead7a92fd1 266 SUPERFAMILY SSF52540 6 262 1.72E-24 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS14215 a204710de2665cdbeb5a57ead7a92fd1 266 Pfam PF13401 AAA domain 42 170 4.6E-21 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS14215 a204710de2665cdbeb5a57ead7a92fd1 266 Gene3D G3DSA:3.40.50.300 23 192 8.0E-11 T 28-03-2018 CIG75_RS03890 a204710de2665cdbeb5a57ead7a92fd1 266 SUPERFAMILY SSF52540 6 262 1.72E-24 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS03890 a204710de2665cdbeb5a57ead7a92fd1 266 Pfam PF13401 AAA domain 42 170 4.6E-21 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS03890 a204710de2665cdbeb5a57ead7a92fd1 266 Gene3D G3DSA:3.40.50.300 23 192 8.0E-11 T 28-03-2018 CIG75_RS13805 a204710de2665cdbeb5a57ead7a92fd1 266 SUPERFAMILY SSF52540 6 262 1.72E-24 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS13805 a204710de2665cdbeb5a57ead7a92fd1 266 Pfam PF13401 AAA domain 42 170 4.6E-21 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS13805 a204710de2665cdbeb5a57ead7a92fd1 266 Gene3D G3DSA:3.40.50.300 23 192 8.0E-11 T 28-03-2018 CIG75_RS05925 a204710de2665cdbeb5a57ead7a92fd1 266 SUPERFAMILY SSF52540 6 262 1.72E-24 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS05925 a204710de2665cdbeb5a57ead7a92fd1 266 Pfam PF13401 AAA domain 42 170 4.6E-21 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS05925 a204710de2665cdbeb5a57ead7a92fd1 266 Gene3D G3DSA:3.40.50.300 23 192 8.0E-11 T 28-03-2018 CIG75_RS03765 ba4ef5c31414f908574e53075a8a404c 326 Gene3D G3DSA:3.30.1060.10 2 175 1.4E-65 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CIG75_RS03765 ba4ef5c31414f908574e53075a8a404c 326 Gene3D G3DSA:2.170.150.20 176 323 1.9E-55 T 28-03-2018 CIG75_RS03765 ba4ef5c31414f908574e53075a8a404c 326 SUPERFAMILY SSF51316 182 323 1.88E-60 T 28-03-2018 IPR011057 Mss4-like CIG75_RS03765 ba4ef5c31414f908574e53075a8a404c 326 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 183 315 9.0E-63 T 28-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 CIG75_RS03765 ba4ef5c31414f908574e53075a8a404c 326 Pfam PF01641 SelR domain 187 306 1.2E-47 T 28-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 CIG75_RS03765 ba4ef5c31414f908574e53075a8a404c 326 Hamap MF_01400 Peptide methionine sulfoxide reductase MsrB [msrB]. 182 307 37.119 T 28-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 CIG75_RS03765 ba4ef5c31414f908574e53075a8a404c 326 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 11 162 2.4E-64 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CIG75_RS03765 ba4ef5c31414f908574e53075a8a404c 326 SUPERFAMILY SSF55068 9 174 3.66E-72 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CIG75_RS03765 ba4ef5c31414f908574e53075a8a404c 326 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 10 169 37.078 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CIG75_RS03765 ba4ef5c31414f908574e53075a8a404c 326 Pfam PF01625 Peptide methionine sulfoxide reductase 13 163 9.5E-60 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CIG75_RS18655 cd3fe7888956d6a4a5000014dd1f0e6e 202 Pfam PF00551 Formyl transferase 3 181 6.3E-56 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CIG75_RS18655 cd3fe7888956d6a4a5000014dd1f0e6e 202 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 3 188 30.732 T 28-03-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 CIG75_RS18655 cd3fe7888956d6a4a5000014dd1f0e6e 202 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 3 191 1.3E-68 T 28-03-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 CIG75_RS18655 cd3fe7888956d6a4a5000014dd1f0e6e 202 SUPERFAMILY SSF53328 3 196 1.11E-59 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CIG75_RS18655 cd3fe7888956d6a4a5000014dd1f0e6e 202 Gene3D G3DSA:3.40.50.170 2 201 2.8E-63 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CIG75_RS07845 a6d74d648e810996fe3910684366bcbb 568 Gene3D G3DSA:3.30.230.10 337 556 8.0E-51 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CIG75_RS07845 a6d74d648e810996fe3910684366bcbb 568 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 348 537 6.2E-32 T 28-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 CIG75_RS07845 a6d74d648e810996fe3910684366bcbb 568 Gene3D G3DSA:1.10.8.60 256 335 4.2E-10 T 28-03-2018 CIG75_RS07845 a6d74d648e810996fe3910684366bcbb 568 Gene3D G3DSA:3.40.50.300 48 255 2.8E-31 T 28-03-2018 CIG75_RS07845 a6d74d648e810996fe3910684366bcbb 568 SUPERFAMILY SSF52540 235 328 9.32E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS07845 a6d74d648e810996fe3910684366bcbb 568 SUPERFAMILY SSF52540 56 204 9.32E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS07845 a6d74d648e810996fe3910684366bcbb 568 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 445 453 - T 28-03-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 CIG75_RS07845 a6d74d648e810996fe3910684366bcbb 568 SUPERFAMILY SSF54211 351 534 6.83E-42 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CIG75_RS07845 a6d74d648e810996fe3910684366bcbb 568 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 93 264 1.4E-17 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CIG75_RS07845 a6d74d648e810996fe3910684366bcbb 568 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 472 491 1.9E-32 T 28-03-2018 CIG75_RS07845 a6d74d648e810996fe3910684366bcbb 568 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 495 513 1.9E-32 T 28-03-2018 CIG75_RS07845 a6d74d648e810996fe3910684366bcbb 568 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 352 368 1.9E-32 T 28-03-2018 CIG75_RS07845 a6d74d648e810996fe3910684366bcbb 568 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 442 461 1.9E-32 T 28-03-2018 CIG75_RS07845 a6d74d648e810996fe3910684366bcbb 568 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 97 116 1.9E-32 T 28-03-2018 CIG75_RS07845 a6d74d648e810996fe3910684366bcbb 568 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 173 188 - T 28-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CIG75_RS07845 a6d74d648e810996fe3910684366bcbb 568 SMART SM00382 89 267 2.8E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS07845 a6d74d648e810996fe3910684366bcbb 568 TIGRFAM TIGR02902 spore_lonB: ATP-dependent protease LonB 6 534 1.2E-274 T 28-03-2018 IPR014251 Sporulation protease LonB CIG75_RS20405 f966ac86748ed1cd723312acd38681ab 169 Gene3D G3DSA:3.40.30.10 35 166 3.4E-12 T 28-03-2018 CIG75_RS20405 f966ac86748ed1cd723312acd38681ab 169 SUPERFAMILY SSF52833 8 154 2.01E-14 T 28-03-2018 IPR012336 Thioredoxin-like fold CIG75_RS20405 f966ac86748ed1cd723312acd38681ab 169 Pfam PF00578 AhpC/TSA family 42 148 1.4E-9 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CIG75_RS16955 a175c3ab666312284b08cb279b33bdb0 364 SUPERFAMILY SSF52733 2 177 3.92E-58 T 28-03-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CIG75_RS16955 a175c3ab666312284b08cb279b33bdb0 364 Gene3D G3DSA:1.10.1610.10 1 54 3.6E-27 T 28-03-2018 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CIG75_RS16955 a175c3ab666312284b08cb279b33bdb0 364 SUPERFAMILY SSF52733 209 361 2.75E-49 T 28-03-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CIG75_RS16955 a175c3ab666312284b08cb279b33bdb0 364 Hamap MF_00230 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [cobT]. 1 363 32.744 T 28-03-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CIG75_RS16955 a175c3ab666312284b08cb279b33bdb0 364 Pfam PF02277 Phosphoribosyltransferase 208 358 1.9E-56 T 28-03-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CIG75_RS16955 a175c3ab666312284b08cb279b33bdb0 364 Pfam PF02277 Phosphoribosyltransferase 2 177 5.5E-68 T 28-03-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CIG75_RS16955 a175c3ab666312284b08cb279b33bdb0 364 Gene3D G3DSA:3.40.50.10210 55 344 2.8E-96 T 28-03-2018 CIG75_RS20280 d90fbee55d40ddefc98c2479fdd96e8d 187 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 14 27 - T 28-03-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 CIG75_RS20280 d90fbee55d40ddefc98c2479fdd96e8d 187 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 1 178 35.3 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CIG75_RS20280 d90fbee55d40ddefc98c2479fdd96e8d 187 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 107 117 - T 28-03-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 CIG75_RS20280 d90fbee55d40ddefc98c2479fdd96e8d 187 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 2 185 1.5E-64 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CIG75_RS20280 d90fbee55d40ddefc98c2479fdd96e8d 187 SUPERFAMILY SSF53178 2 185 1.44E-67 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CIG75_RS20280 d90fbee55d40ddefc98c2479fdd96e8d 187 Gene3D G3DSA:3.40.50.1470 1 187 5.1E-73 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CIG75_RS20280 d90fbee55d40ddefc98c2479fdd96e8d 187 Pfam PF01195 Peptidyl-tRNA hydrolase 3 185 3.9E-57 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CIG75_RS14545 be88670c616ac569fcedcc9d1b0ed4fe 209 SUPERFAMILY SSF53335 10 209 1.33E-41 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CIG75_RS14545 be88670c616ac569fcedcc9d1b0ed4fe 209 Pfam PF01596 O-methyltransferase 14 207 7.6E-48 T 28-03-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 CIG75_RS14545 be88670c616ac569fcedcc9d1b0ed4fe 209 Gene3D G3DSA:3.40.50.150 2 208 6.1E-31 T 28-03-2018 CIG75_RS04715 ec35123b1ee62581aebc04b844afe5dc 784 Gene3D G3DSA:3.40.390.10 151 422 5.0E-4 T 28-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 CIG75_RS04715 ec35123b1ee62581aebc04b844afe5dc 784 SUPERFAMILY SSF55486 268 301 1.04E-13 T 28-03-2018 CIG75_RS04715 ec35123b1ee62581aebc04b844afe5dc 784 SUPERFAMILY SSF55486 342 406 1.04E-13 T 28-03-2018 CIG75_RS04715 ec35123b1ee62581aebc04b844afe5dc 784 TIGRFAM TIGR03296 M6dom_TIGR03296: M6 family metalloprotease domain 170 455 3.0E-70 T 28-03-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 CIG75_RS04715 ec35123b1ee62581aebc04b844afe5dc 784 PIRSF PIRSF007519 1 784 5.5E-254 T 28-03-2018 IPR012300 Peptidase M6, InhA CIG75_RS04715 ec35123b1ee62581aebc04b844afe5dc 784 Pfam PF05547 Immune inhibitor A peptidase M6 134 780 8.9E-229 T 28-03-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 CIG75_RS04715 ec35123b1ee62581aebc04b844afe5dc 784 Gene3D G3DSA:2.60.120.260 429 597 8.2E-26 T 28-03-2018 IPR008979 Galactose-binding domain-like CIG75_RS12965 5a5080ee351c6124d9bf6aafbf430089 77 SUPERFAMILY SSF47413 4 70 6.19E-9 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CIG75_RS12965 5a5080ee351c6124d9bf6aafbf430089 77 Gene3D G3DSA:1.10.260.40 3 76 4.8E-12 T 28-03-2018 CIG75_RS12965 5a5080ee351c6124d9bf6aafbf430089 77 SMART SM00530 5 66 5.6E-5 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS12965 5a5080ee351c6124d9bf6aafbf430089 77 Pfam PF12844 Helix-turn-helix domain 5 67 8.6E-8 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS06725 121f75eb52a31d480a3abcc10c24ca61 78 Gene3D G3DSA:1.10.1200.10 4 78 6.1E-13 T 28-03-2018 CIG75_RS06725 121f75eb52a31d480a3abcc10c24ca61 78 Pfam PF00550 Phosphopantetheine attachment site 9 73 2.9E-7 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS06725 121f75eb52a31d480a3abcc10c24ca61 78 SUPERFAMILY SSF47336 7 76 1.03E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS03410 637c47fb4bcf149a08045e1f15ced788 359 PRINTS PR00344 Bacterial sensor protein C-terminal signature 286 300 1.6E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS03410 637c47fb4bcf149a08045e1f15ced788 359 PRINTS PR00344 Bacterial sensor protein C-terminal signature 329 342 1.6E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS03410 637c47fb4bcf149a08045e1f15ced788 359 PRINTS PR00344 Bacterial sensor protein C-terminal signature 305 323 1.6E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS03410 637c47fb4bcf149a08045e1f15ced788 359 Pfam PF13426 PAS domain 21 123 6.5E-12 T 28-03-2018 IPR000014 PAS domain CIG75_RS03410 637c47fb4bcf149a08045e1f15ced788 359 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 11 130 1.5E-17 T 28-03-2018 IPR000014 PAS domain CIG75_RS03410 637c47fb4bcf149a08045e1f15ced788 359 Gene3D G3DSA:3.30.565.10 125 344 1.4E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS03410 637c47fb4bcf149a08045e1f15ced788 359 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 251 344 6.0E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS03410 637c47fb4bcf149a08045e1f15ced788 359 SMART SM00091 10 81 5.1E-4 T 28-03-2018 IPR000014 PAS domain CIG75_RS03410 637c47fb4bcf149a08045e1f15ced788 359 SUPERFAMILY SSF55785 21 131 2.26E-17 T 28-03-2018 IPR000014 PAS domain CIG75_RS03410 637c47fb4bcf149a08045e1f15ced788 359 PIRSF PIRSF037432 5 343 6.9E-84 T 28-03-2018 IPR017203 Signal transduction histidine kinase, NreB GO:0000155|GO:0004673|GO:0005506|GO:0005524|GO:0005737|GO:0018106 CIG75_RS03410 637c47fb4bcf149a08045e1f15ced788 359 Pfam PF07730 Histidine kinase 147 212 4.4E-15 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CIG75_RS03410 637c47fb4bcf149a08045e1f15ced788 359 SMART SM00387 250 345 6.0E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS03410 637c47fb4bcf149a08045e1f15ced788 359 Gene3D G3DSA:3.30.450.20 4 124 1.1E-21 T 28-03-2018 CIG75_RS03410 637c47fb4bcf149a08045e1f15ced788 359 SUPERFAMILY SSF55874 213 343 3.27E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS17160 4b4617e51af407c1a262cad71b649dc8 107 Pfam PF00381 PTS HPr component phosphorylation site 26 105 3.7E-30 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CIG75_RS17160 4b4617e51af407c1a262cad71b649dc8 107 SUPERFAMILY SSF55594 27 106 3.66E-26 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CIG75_RS17160 4b4617e51af407c1a262cad71b649dc8 107 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 36 43 - T 28-03-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site CIG75_RS17160 4b4617e51af407c1a262cad71b649dc8 107 PRINTS PR00107 Phosphocarrier protein signature 76 93 3.0E-21 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CIG75_RS17160 4b4617e51af407c1a262cad71b649dc8 107 PRINTS PR00107 Phosphocarrier protein signature 36 52 3.0E-21 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CIG75_RS17160 4b4617e51af407c1a262cad71b649dc8 107 PRINTS PR00107 Phosphocarrier protein signature 61 76 3.0E-21 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CIG75_RS17160 4b4617e51af407c1a262cad71b649dc8 107 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 62 77 - T 28-03-2018 IPR002114 Phosphotransferase system, HPr serine phosphorylation site CIG75_RS17160 4b4617e51af407c1a262cad71b649dc8 107 Gene3D G3DSA:3.30.1340.10 21 105 5.4E-32 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CIG75_RS17160 4b4617e51af407c1a262cad71b649dc8 107 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 25 104 6.7E-30 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CIG75_RS00070 656d0f8fafc2dba0a97f8487c0d55372 103 Pfam PF02575 YbaB/EbfC DNA-binding family 8 98 1.5E-34 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CIG75_RS00070 656d0f8fafc2dba0a97f8487c0d55372 103 SUPERFAMILY SSF82607 8 102 7.85E-33 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CIG75_RS00070 656d0f8fafc2dba0a97f8487c0d55372 103 PIRSF PIRSF004555 1 103 7.3E-37 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CIG75_RS00070 656d0f8fafc2dba0a97f8487c0d55372 103 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 2 96 22.348 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CIG75_RS00070 656d0f8fafc2dba0a97f8487c0d55372 103 Gene3D G3DSA:3.30.1310.10 1 103 1.3E-36 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CIG75_RS00070 656d0f8fafc2dba0a97f8487c0d55372 103 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 2 102 1.7E-27 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CIG75_RS09325 4b5041b722608f121f68b7b0f598f409 440 Pfam PF14620 YpeB sporulation 13 372 1.8E-114 T 28-03-2018 IPR014239 Spore germination YpeB GO:0009847 CIG75_RS09325 4b5041b722608f121f68b7b0f598f409 440 TIGRFAM TIGR02889 spore_YpeB: germination protein YpeB 5 439 1.2E-119 T 28-03-2018 IPR014239 Spore germination YpeB GO:0009847 CIG75_RS09325 4b5041b722608f121f68b7b0f598f409 440 Gene3D G3DSA:3.90.20.10 2 68 0.0061 T 28-03-2018 CIG75_RS06610 5287c3cc75f7748c8c0e4b591e341922 1110 Gene3D G3DSA:2.30.38.10 808 889 2.4E-24 T 28-03-2018 CIG75_RS06610 5287c3cc75f7748c8c0e4b591e341922 1110 Gene3D G3DSA:3.40.50.980 491 647 5.4E-51 T 28-03-2018 CIG75_RS06610 5287c3cc75f7748c8c0e4b591e341922 1110 SUPERFAMILY SSF56801 460 1019 3.27E-164 T 28-03-2018 CIG75_RS06610 5287c3cc75f7748c8c0e4b591e341922 1110 Gene3D G3DSA:3.30.300.30 891 1011 2.3E-42 T 28-03-2018 CIG75_RS06610 5287c3cc75f7748c8c0e4b591e341922 1110 Pfam PF00668 Condensation domain 43 477 5.3E-112 T 28-03-2018 IPR001242 Condensation domain CIG75_RS06610 5287c3cc75f7748c8c0e4b591e341922 1110 Gene3D G3DSA:3.30.559.10 28 237 3.9E-49 T 28-03-2018 CIG75_RS06610 5287c3cc75f7748c8c0e4b591e341922 1110 Pfam PF13193 AMP-binding enzyme C-terminal domain 904 979 5.0E-16 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS06610 5287c3cc75f7748c8c0e4b591e341922 1110 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 521 919 1.0E-133 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS06610 5287c3cc75f7748c8c0e4b591e341922 1110 Gene3D G3DSA:1.10.1200.10 1012 1107 5.4E-19 T 28-03-2018 CIG75_RS06610 5287c3cc75f7748c8c0e4b591e341922 1110 SUPERFAMILY SSF47336 998 1071 1.57E-16 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS06610 5287c3cc75f7748c8c0e4b591e341922 1110 SUPERFAMILY SSF52777 45 215 6.56E-53 T 28-03-2018 CIG75_RS06610 5287c3cc75f7748c8c0e4b591e341922 1110 PIRSF PIRSF001617 865 947 1.4E-21 T 28-03-2018 CIG75_RS06610 5287c3cc75f7748c8c0e4b591e341922 1110 PIRSF PIRSF001617 618 867 9.9E-12 T 28-03-2018 CIG75_RS06610 5287c3cc75f7748c8c0e4b591e341922 1110 PIRSF PIRSF001617 943 1107 1.7E-20 T 28-03-2018 CIG75_RS06610 5287c3cc75f7748c8c0e4b591e341922 1110 PIRSF PIRSF001617 223 612 6.1E-22 T 28-03-2018 CIG75_RS06610 5287c3cc75f7748c8c0e4b591e341922 1110 SUPERFAMILY SSF52777 222 486 5.0E-68 T 28-03-2018 CIG75_RS06610 5287c3cc75f7748c8c0e4b591e341922 1110 ProSitePatterns PS00455 Putative AMP-binding domain signature. 642 653 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS06610 5287c3cc75f7748c8c0e4b591e341922 1110 Pfam PF00550 Phosphopantetheine attachment site 1009 1071 5.1E-10 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS06610 5287c3cc75f7748c8c0e4b591e341922 1110 Gene3D G3DSA:3.40.50.980 648 802 5.8E-28 T 28-03-2018 CIG75_RS06610 5287c3cc75f7748c8c0e4b591e341922 1110 Pfam PF00501 AMP-binding enzyme 500 896 3.9E-101 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS03630 62f867766861457de9ea528664dcaab7 353 Gene3D G3DSA:1.10.1660.10 60 142 1.1E-6 T 28-03-2018 CIG75_RS03630 62f867766861457de9ea528664dcaab7 353 Pfam PF13411 MerR HTH family regulatory protein 5 72 1.5E-17 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CIG75_RS03630 62f867766861457de9ea528664dcaab7 353 SUPERFAMILY SSF46955 4 111 2.6E-24 T 28-03-2018 IPR009061 Putative DNA-binding domain CIG75_RS03630 62f867766861457de9ea528664dcaab7 353 SMART SM00422 4 73 2.6E-14 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CIG75_RS03630 62f867766861457de9ea528664dcaab7 353 Gene3D G3DSA:1.10.1660.10 1 59 1.4E-20 T 28-03-2018 CIG75_RS03630 62f867766861457de9ea528664dcaab7 353 Gene3D G3DSA:3.40.50.150 147 348 2.2E-32 T 28-03-2018 CIG75_RS03630 62f867766861457de9ea528664dcaab7 353 Pfam PF13649 Methyltransferase domain 190 279 3.5E-20 T 28-03-2018 CIG75_RS03630 62f867766861457de9ea528664dcaab7 353 SUPERFAMILY SSF53335 147 333 3.53E-36 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CIG75_RS00835 aa007e130a67f45cc96c5ad3043f1737 268 SUPERFAMILY SSF55347 83 216 8.34E-9 T 28-03-2018 CIG75_RS17285 7a50e2c897f708b9e1d8a131b3b753c4 85 ProDom PD007559 HYDRATASE NITRILE ALPHA SUBUNIT LYASE CHAIN METAL-BINDING DIRECT SEQUENCING NITRILASE 10 60 0.006 T 28-03-2018 IPR004232 Nitrile hydratase alpha /Thiocyanate hydrolase gamma GO:0003824|GO:0006807|GO:0046914 KEGG: 00364+4.2.1.84|KEGG: 00380+4.2.1.84|KEGG: 00627+4.2.1.84|KEGG: 00643+4.2.1.84|MetaCyc: PWY-5025|MetaCyc: PWY-581|MetaCyc: PWY-7308 CIG75_RS17285 7a50e2c897f708b9e1d8a131b3b753c4 85 Gene3D G3DSA:3.90.330.10 2 77 5.2E-9 T 28-03-2018 IPR004232 Nitrile hydratase alpha /Thiocyanate hydrolase gamma GO:0003824|GO:0006807|GO:0046914 KEGG: 00364+4.2.1.84|KEGG: 00380+4.2.1.84|KEGG: 00627+4.2.1.84|KEGG: 00643+4.2.1.84|MetaCyc: PWY-5025|MetaCyc: PWY-581|MetaCyc: PWY-7308 CIG75_RS17285 7a50e2c897f708b9e1d8a131b3b753c4 85 SUPERFAMILY SSF56209 5 73 2.88E-11 T 28-03-2018 IPR004232 Nitrile hydratase alpha /Thiocyanate hydrolase gamma GO:0003824|GO:0006807|GO:0046914 KEGG: 00364+4.2.1.84|KEGG: 00380+4.2.1.84|KEGG: 00627+4.2.1.84|KEGG: 00643+4.2.1.84|MetaCyc: PWY-5025|MetaCyc: PWY-581|MetaCyc: PWY-7308 CIG75_RS11505 b4d16b8438fac4266278bccdb3219fe4 330 Gene3D G3DSA:3.30.1220.10 223 325 2.0E-7 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CIG75_RS11505 b4d16b8438fac4266278bccdb3219fe4 330 Gene3D G3DSA:3.40.50.300 1 205 1.7E-34 T 28-03-2018 CIG75_RS11505 b4d16b8438fac4266278bccdb3219fe4 330 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 240 323 4.5E-8 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CIG75_RS11505 b4d16b8438fac4266278bccdb3219fe4 330 SMART SM00833 239 324 0.0028 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CIG75_RS11505 b4d16b8438fac4266278bccdb3219fe4 330 SUPERFAMILY SSF52540 3 188 6.65E-27 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS11505 b4d16b8438fac4266278bccdb3219fe4 330 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 4 187 1.3E-44 T 28-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain CIG75_RS11505 b4d16b8438fac4266278bccdb3219fe4 330 SUPERFAMILY SSF90002 240 323 1.19E-7 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CIG75_RS01430 5f1e83cf64d3c92722d13f647aea0090 722 SUPERFAMILY SSF56601 304 692 1.61E-122 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CIG75_RS01430 5f1e83cf64d3c92722d13f647aea0090 722 SUPERFAMILY SSF56601 254 276 1.61E-122 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CIG75_RS01430 5f1e83cf64d3c92722d13f647aea0090 722 Pfam PF00905 Penicillin binding protein transpeptidase domain 365 633 3.4E-30 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CIG75_RS01430 5f1e83cf64d3c92722d13f647aea0090 722 Gene3D G3DSA:1.10.3810.10 88 289 3.0E-74 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 CIG75_RS01430 5f1e83cf64d3c92722d13f647aea0090 722 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 109 638 2.0E-179 T 28-03-2018 CIG75_RS01430 5f1e83cf64d3c92722d13f647aea0090 722 Pfam PF00912 Transglycosylase 105 272 3.3E-61 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 CIG75_RS01430 5f1e83cf64d3c92722d13f647aea0090 722 Gene3D G3DSA:3.40.710.10 292 687 1.1E-117 T 28-03-2018 CIG75_RS01430 5f1e83cf64d3c92722d13f647aea0090 722 SUPERFAMILY SSF53955 88 296 2.81E-74 T 28-03-2018 IPR023346 Lysozyme-like domain CIG75_RS02415 f4a8ef7d3b0632424d8eb7e6db0bc151 336 SUPERFAMILY SSF51735 3 324 1.68E-91 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS02415 f4a8ef7d3b0632424d8eb7e6db0bc151 336 Gene3D G3DSA:3.40.50.720 1 190 1.6E-44 T 28-03-2018 CIG75_RS02415 f4a8ef7d3b0632424d8eb7e6db0bc151 336 Pfam PF16363 GDP-mannose 4,6 dehydratase 9 309 1.6E-71 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS02415 f4a8ef7d3b0632424d8eb7e6db0bc151 336 Gene3D G3DSA:3.90.25.10 191 334 1.0E-31 T 28-03-2018 CIG75_RS02415 f4a8ef7d3b0632424d8eb7e6db0bc151 336 TIGRFAM TIGR04180 EDH_00030: NAD dependent epimerase/dehydratase, LLPSF_EDH_00030 family 8 303 3.2E-165 T 28-03-2018 IPR026390 NAD dependent epimerase/dehydratase, LLPSF_EDH_00030 family CIG75_RS03230 9491cdab41ee11ac6fe906f17ca09760 1131 Pfam PF12902 Ferritin-like 17 330 1.5E-22 T 28-03-2018 CIG75_RS10290 f6b331262c9f1ecb9fcc3e3f1d728537 298 Pfam PF07070 SpoOM protein 4 199 7.4E-42 T 28-03-2018 IPR009776 Sporulation stage 0, protein M CIG75_RS17315 c9234dbd1fc7ef8a25c35ea813daf254 380 Gene3D G3DSA:3.20.20.70 2 302 4.5E-23 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CIG75_RS17315 c9234dbd1fc7ef8a25c35ea813daf254 380 SUPERFAMILY SSF102114 83 295 3.27E-25 T 28-03-2018 CIG75_RS17315 c9234dbd1fc7ef8a25c35ea813daf254 380 Pfam PF13353 4Fe-4S single cluster domain 92 160 8.8E-7 T 28-03-2018 CIG75_RS17315 c9234dbd1fc7ef8a25c35ea813daf254 380 Pfam PF04055 Radical SAM superfamily 92 248 1.8E-10 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CIG75_RS04745 cafac78e834950aeecb1f0a548c8dc49 130 Gene3D G3DSA:3.10.129.10 1 130 2.2E-34 T 28-03-2018 CIG75_RS04745 cafac78e834950aeecb1f0a548c8dc49 130 SUPERFAMILY SSF54637 5 128 1.68E-36 T 28-03-2018 IPR029069 HotDog domain CIG75_RS04745 cafac78e834950aeecb1f0a548c8dc49 130 PIRSF PIRSF003230 1 130 7.8E-21 T 28-03-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 CIG75_RS04745 cafac78e834950aeecb1f0a548c8dc49 130 Pfam PF13279 Thioesterase-like superfamily 9 127 1.9E-18 T 28-03-2018 CIG75_RS04745 cafac78e834950aeecb1f0a548c8dc49 130 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 9 119 1.7E-22 T 28-03-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 CIG75_RS15735 ae16cf114eaa784be23708d02f64de08 561 Gene3D G3DSA:1.10.287.950 310 513 2.2E-53 T 28-03-2018 CIG75_RS15735 ae16cf114eaa784be23708d02f64de08 561 Gene3D G3DSA:1.10.287.950 514 561 1.9E-7 T 28-03-2018 CIG75_RS15735 ae16cf114eaa784be23708d02f64de08 561 SUPERFAMILY SSF58104 228 258 3.4E-73 T 28-03-2018 CIG75_RS15735 ae16cf114eaa784be23708d02f64de08 561 SUPERFAMILY SSF58104 291 559 3.4E-73 T 28-03-2018 CIG75_RS15735 ae16cf114eaa784be23708d02f64de08 561 Pfam PF17202 Single cache domain 3 74 176 1.9E-31 T 28-03-2018 IPR033463 Single cache domain 3 CIG75_RS15735 ae16cf114eaa784be23708d02f64de08 561 SMART SM00304 203 256 1.3E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CIG75_RS15735 ae16cf114eaa784be23708d02f64de08 561 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 1 25 4.6E-22 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CIG75_RS15735 ae16cf114eaa784be23708d02f64de08 561 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 412 441 4.6E-22 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CIG75_RS15735 ae16cf114eaa784be23708d02f64de08 561 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 383 410 4.6E-22 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CIG75_RS15735 ae16cf114eaa784be23708d02f64de08 561 Pfam PF00672 HAMP domain 207 253 9.3E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CIG75_RS15735 ae16cf114eaa784be23708d02f64de08 561 Gene3D G3DSA:1.10.287.950 188 301 8.4E-7 T 28-03-2018 CIG75_RS15735 ae16cf114eaa784be23708d02f64de08 561 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 330 513 1.4E-51 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CIG75_RS15735 ae16cf114eaa784be23708d02f64de08 561 SUPERFAMILY SSF103190 64 176 2.16E-11 T 28-03-2018 IPR029151 Periplasmic sensor domain-like CIG75_RS15735 ae16cf114eaa784be23708d02f64de08 561 Gene3D G3DSA:3.30.450.20 36 178 8.2E-6 T 28-03-2018 CIG75_RS15735 ae16cf114eaa784be23708d02f64de08 561 SMART SM00283 285 560 6.3E-87 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CIG75_RS14650 acb0de1bd64cf04e5781844f6b409b25 385 Pfam PF04545 Sigma-70, region 4 320 373 5.9E-20 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS14650 acb0de1bd64cf04e5781844f6b409b25 385 SUPERFAMILY SSF88946 113 222 6.28E-54 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS14650 acb0de1bd64cf04e5781844f6b409b25 385 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 148 373 6.1E-39 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS14650 acb0de1bd64cf04e5781844f6b409b25 385 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 5 385 35.003 T 28-03-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 CIG75_RS14650 acb0de1bd64cf04e5781844f6b409b25 385 Gene3D G3DSA:1.10.601.10 1 221 1.8E-83 T 28-03-2018 CIG75_RS14650 acb0de1bd64cf04e5781844f6b409b25 385 Pfam PF04539 Sigma-70 region 3 231 307 3.7E-32 T 28-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS14650 acb0de1bd64cf04e5781844f6b409b25 385 SUPERFAMILY SSF88659 282 383 4.3E-30 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS14650 acb0de1bd64cf04e5781844f6b409b25 385 Gene3D G3DSA:1.10.10.10 314 385 5.4E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS14650 acb0de1bd64cf04e5781844f6b409b25 385 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 176 189 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS14650 acb0de1bd64cf04e5781844f6b409b25 385 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 345 371 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS14650 acb0de1bd64cf04e5781844f6b409b25 385 SUPERFAMILY SSF88659 225 298 8.28E-24 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS14650 acb0de1bd64cf04e5781844f6b409b25 385 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 148 384 5.7E-124 T 28-03-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 CIG75_RS14650 acb0de1bd64cf04e5781844f6b409b25 385 Pfam PF03979 Sigma-70 factor, region 1.1 16 87 4.6E-17 T 28-03-2018 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 CIG75_RS14650 acb0de1bd64cf04e5781844f6b409b25 385 Gene3D G3DSA:1.10.10.10 222 272 2.4E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS14650 acb0de1bd64cf04e5781844f6b409b25 385 Pfam PF04542 Sigma-70 region 2 152 221 3.1E-22 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS14650 acb0de1bd64cf04e5781844f6b409b25 385 Pfam PF00140 Sigma-70 factor, region 1.2 114 147 3.5E-18 T 28-03-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS14650 acb0de1bd64cf04e5781844f6b409b25 385 PRINTS PR00046 Major sigma-70 factor signature 200 208 2.7E-32 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS14650 acb0de1bd64cf04e5781844f6b409b25 385 PRINTS PR00046 Major sigma-70 factor signature 345 360 2.7E-32 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS14650 acb0de1bd64cf04e5781844f6b409b25 385 PRINTS PR00046 Major sigma-70 factor signature 324 336 2.7E-32 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS14650 acb0de1bd64cf04e5781844f6b409b25 385 PRINTS PR00046 Major sigma-70 factor signature 176 189 2.7E-32 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS14650 acb0de1bd64cf04e5781844f6b409b25 385 PRINTS PR00046 Major sigma-70 factor signature 360 371 2.7E-32 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS08225 cd85e2ebd59e5189b44b637bbf88bbc4 314 Pfam PF01695 IstB-like ATP binding protein 164 292 5.4E-15 T 28-03-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 CIG75_RS08225 cd85e2ebd59e5189b44b637bbf88bbc4 314 SUPERFAMILY SSF52540 157 278 5.94E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS08225 cd85e2ebd59e5189b44b637bbf88bbc4 314 Gene3D G3DSA:3.40.50.300 116 297 1.1E-13 T 28-03-2018 CIG75_RS08225 cd85e2ebd59e5189b44b637bbf88bbc4 314 SMART SM00382 162 297 1.3E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS03060 55f50b3413321d4683e1b5d8957a4a6d 382 SUPERFAMILY SSF103473 7 377 1.26E-65 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS03060 55f50b3413321d4683e1b5d8957a4a6d 382 Pfam PF07690 Major Facilitator Superfamily 13 336 1.1E-45 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CIG75_RS03060 55f50b3413321d4683e1b5d8957a4a6d 382 Gene3D G3DSA:1.20.1250.20 1 191 1.2E-32 T 28-03-2018 CIG75_RS03060 55f50b3413321d4683e1b5d8957a4a6d 382 ProSitePatterns PS00216 Sugar transport proteins signature 1. 62 78 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CIG75_RS03060 55f50b3413321d4683e1b5d8957a4a6d 382 Gene3D G3DSA:1.20.1250.20 195 381 2.2E-29 T 28-03-2018 CIG75_RS06745 a7e86271a48229c16b685052df48a486 1049 Gene3D G3DSA:3.30.300.30 840 954 3.1E-41 T 28-03-2018 CIG75_RS06745 a7e86271a48229c16b685052df48a486 1049 SUPERFAMILY SSF52777 196 460 1.45E-67 T 28-03-2018 CIG75_RS06745 a7e86271a48229c16b685052df48a486 1049 Gene3D G3DSA:1.10.1200.10 955 1028 2.8E-21 T 28-03-2018 CIG75_RS06745 a7e86271a48229c16b685052df48a486 1049 Pfam PF00550 Phosphopantetheine attachment site 953 1015 8.1E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS06745 a7e86271a48229c16b685052df48a486 1049 Gene3D G3DSA:3.40.50.980 464 603 4.4E-44 T 28-03-2018 CIG75_RS06745 a7e86271a48229c16b685052df48a486 1049 SUPERFAMILY SSF47336 943 1015 8.51E-19 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS06745 a7e86271a48229c16b685052df48a486 1049 SUPERFAMILY SSF56801 431 964 1.18E-160 T 28-03-2018 CIG75_RS06745 a7e86271a48229c16b685052df48a486 1049 Gene3D G3DSA:3.40.50.980 604 757 2.8E-39 T 28-03-2018 CIG75_RS06745 a7e86271a48229c16b685052df48a486 1049 Pfam PF00501 AMP-binding enzyme 473 845 1.1E-98 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS06745 a7e86271a48229c16b685052df48a486 1049 Gene3D G3DSA:3.30.559.10 2 209 4.0E-45 T 28-03-2018 CIG75_RS06745 a7e86271a48229c16b685052df48a486 1049 SMART SM00823 Phosphopantetheine attachment site 948 1019 0.0064 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS06745 a7e86271a48229c16b685052df48a486 1049 Pfam PF13193 AMP-binding enzyme C-terminal domain 853 923 6.9E-14 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS06745 a7e86271a48229c16b685052df48a486 1049 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 494 869 1.4E-129 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS06745 a7e86271a48229c16b685052df48a486 1049 ProSitePatterns PS00455 Putative AMP-binding domain signature. 598 609 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS06745 a7e86271a48229c16b685052df48a486 1049 SUPERFAMILY SSF52777 11 188 2.67E-51 T 28-03-2018 CIG75_RS06745 a7e86271a48229c16b685052df48a486 1049 Pfam PF00668 Condensation domain 10 453 2.0E-119 T 28-03-2018 IPR001242 Condensation domain CIG75_RS06745 a7e86271a48229c16b685052df48a486 1049 Gene3D G3DSA:2.30.38.10 758 838 1.2E-23 T 28-03-2018 CIG75_RS07475 40ab5a35e9595faac755b26b6119000a 327 SUPERFAMILY SSF143865 1 261 4.32E-65 T 28-03-2018 CIG75_RS07475 40ab5a35e9595faac755b26b6119000a 327 Gene3D G3DSA:1.20.58.340 139 259 5.2E-27 T 28-03-2018 CIG75_RS07475 40ab5a35e9595faac755b26b6119000a 327 Pfam PF01544 CorA-like Mg2+ transporter protein 32 318 3.3E-69 T 28-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 CIG75_RS07475 40ab5a35e9595faac755b26b6119000a 327 TIGRFAM TIGR00383 corA: magnesium and cobalt transport protein CorA 23 327 3.8E-61 T 28-03-2018 IPR004488 Magnesium/cobalt transport protein CorA GO:0006824|GO:0015087|GO:0015095|GO:0015693|GO:0016020 CIG75_RS07475 40ab5a35e9595faac755b26b6119000a 327 SUPERFAMILY SSF144083 263 324 2.62E-14 T 28-03-2018 CIG75_RS07475 40ab5a35e9595faac755b26b6119000a 327 Gene3D G3DSA:1.20.58.340 260 327 2.6E-16 T 28-03-2018 CIG75_RS07475 40ab5a35e9595faac755b26b6119000a 327 Gene3D G3DSA:3.30.460.20 1 138 5.1E-32 T 28-03-2018 CIG75_RS17185 d2cab182898892de41a3ba9f903d26b4 681 PRINTS PR00315 GTP-binding elongation factor signature 50 63 2.0E-6 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CIG75_RS17185 d2cab182898892de41a3ba9f903d26b4 681 PRINTS PR00315 GTP-binding elongation factor signature 155 164 2.0E-6 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CIG75_RS17185 d2cab182898892de41a3ba9f903d26b4 681 PRINTS PR00315 GTP-binding elongation factor signature 102 112 2.0E-6 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CIG75_RS17185 d2cab182898892de41a3ba9f903d26b4 681 PRINTS PR00315 GTP-binding elongation factor signature 118 129 2.0E-6 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CIG75_RS17185 d2cab182898892de41a3ba9f903d26b4 681 Pfam PF03144 Elongation factor Tu domain 2 239 305 6.9E-12 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CIG75_RS17185 d2cab182898892de41a3ba9f903d26b4 681 SUPERFAMILY SSF46785 623 675 1.33E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS17185 d2cab182898892de41a3ba9f903d26b4 681 Gene3D G3DSA:2.40.30.10 329 396 1.4E-23 T 28-03-2018 CIG75_RS17185 d2cab182898892de41a3ba9f903d26b4 681 SUPERFAMILY SSF50447 219 309 2.75E-25 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CIG75_RS17185 d2cab182898892de41a3ba9f903d26b4 681 Gene3D G3DSA:1.10.10.10 402 537 6.6E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS17185 d2cab182898892de41a3ba9f903d26b4 681 Gene3D G3DSA:1.10.10.10 557 614 1.0E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS17185 d2cab182898892de41a3ba9f903d26b4 681 Gene3D G3DSA:1.10.10.10 617 674 2.7E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS17185 d2cab182898892de41a3ba9f903d26b4 681 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 52 209 1.4E-16 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CIG75_RS17185 d2cab182898892de41a3ba9f903d26b4 681 Pfam PF00009 Elongation factor Tu GTP binding domain 49 209 1.6E-33 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CIG75_RS17185 d2cab182898892de41a3ba9f903d26b4 681 SUPERFAMILY SSF50465 312 407 2.19E-24 T 28-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal CIG75_RS17185 d2cab182898892de41a3ba9f903d26b4 681 SUPERFAMILY SSF52540 47 240 3.44E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS17185 d2cab182898892de41a3ba9f903d26b4 681 Pfam PF09107 Elongation factor SelB, winged helix 631 674 1.3E-16 T 28-03-2018 IPR015191 Translation elongation factor SelB, winged helix, type 3 GO:0001514|GO:0003723|GO:0003746|GO:0005525|GO:0005737 CIG75_RS17185 d2cab182898892de41a3ba9f903d26b4 681 Gene3D G3DSA:3.40.50.300 30 216 5.0E-37 T 28-03-2018 CIG75_RS17185 d2cab182898892de41a3ba9f903d26b4 681 SUPERFAMILY SSF46785 556 614 3.4E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS17185 d2cab182898892de41a3ba9f903d26b4 681 TIGRFAM TIGR00475 selB: selenocysteine-specific translation elongation factor 50 672 3.0E-114 T 28-03-2018 IPR004535 Translation elongation factor, selenocysteine-specific GO:0001514|GO:0003723|GO:0003746|GO:0005525|GO:0005737 CIG75_RS17185 d2cab182898892de41a3ba9f903d26b4 681 Gene3D G3DSA:2.40.30.10 220 328 1.1E-32 T 28-03-2018 CIG75_RS14655 595c9a4adea180bdc831ee10fdb03803 622 Pfam PF08275 DNA primase catalytic core, N-terminal domain 128 255 3.5E-44 T 28-03-2018 IPR013264 DNA primase, catalytic core, N-terminal CIG75_RS14655 595c9a4adea180bdc831ee10fdb03803 622 Pfam PF10410 DnaB-helicase binding domain of primase 374 427 4.8E-6 T 28-03-2018 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 CIG75_RS14655 595c9a4adea180bdc831ee10fdb03803 622 Gene3D G3DSA:1.10.860.10 473 572 3.1E-7 T 28-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal CIG75_RS14655 595c9a4adea180bdc831ee10fdb03803 622 SUPERFAMILY SSF48024 468 541 8.37E-6 T 28-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CIG75_RS14655 595c9a4adea180bdc831ee10fdb03803 622 Pfam PF01807 CHC2 zinc finger 6 100 5.8E-38 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CIG75_RS14655 595c9a4adea180bdc831ee10fdb03803 622 Gene3D G3DSA:3.90.580.10 1 103 4.5E-37 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CIG75_RS14655 595c9a4adea180bdc831ee10fdb03803 622 PIRSF PIRSF002811 2 613 2.2E-177 T 28-03-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 CIG75_RS14655 595c9a4adea180bdc831ee10fdb03803 622 SUPERFAMILY SSF57783 4 101 3.23E-38 T 28-03-2018 CIG75_RS14655 595c9a4adea180bdc831ee10fdb03803 622 Pfam PF13662 Toprim domain 263 335 2.9E-17 T 28-03-2018 IPR006171 TOPRIM domain CIG75_RS14655 595c9a4adea180bdc831ee10fdb03803 622 Gene3D G3DSA:3.40.1360.10 244 370 1.4E-31 T 28-03-2018 CIG75_RS14655 595c9a4adea180bdc831ee10fdb03803 622 SMART SM00493 262 333 1.6E-12 T 28-03-2018 IPR006171 TOPRIM domain CIG75_RS14655 595c9a4adea180bdc831ee10fdb03803 622 Gene3D G3DSA:3.90.980.10 109 243 4.1E-48 T 28-03-2018 IPR013264 DNA primase, catalytic core, N-terminal CIG75_RS14655 595c9a4adea180bdc831ee10fdb03803 622 SMART SM00400 36 90 1.2E-33 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CIG75_RS14655 595c9a4adea180bdc831ee10fdb03803 622 SUPERFAMILY SSF56731 116 428 7.06E-102 T 28-03-2018 CIG75_RS14655 595c9a4adea180bdc831ee10fdb03803 622 TIGRFAM TIGR01391 dnaG: DNA primase 5 423 2.1E-146 T 28-03-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 CIG75_RS14655 595c9a4adea180bdc831ee10fdb03803 622 Hamap MF_00974 DNA primase [dnaG]. 4 603 29.342 T 28-03-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 CIG75_RS16795 e8677255ec3083a5febd91eb50b1f92d 611 Pfam PF06276 Ferric iron reductase FhuF-like transporter 434 588 2.8E-32 T 28-03-2018 IPR022770 Ferric iron reductase FhuF domain CIG75_RS16795 e8677255ec3083a5febd91eb50b1f92d 611 Pfam PF04183 IucA / IucC family 169 401 5.7E-52 T 28-03-2018 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0015343|GO:0019290 CIG75_RS15870 6491fe6bac4b4f4f7ce301cefc065af2 394 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 324 348 - T 28-03-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 CIG75_RS15870 6491fe6bac4b4f4f7ce301cefc065af2 394 Pfam PF01098 Cell cycle protein 12 366 2.2E-103 T 28-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 CIG75_RS15870 6491fe6bac4b4f4f7ce301cefc065af2 394 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 9 365 1.3E-104 T 28-03-2018 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 CIG75_RS12465 ff800d87006226f56273220590f91e35 63 TIGRFAM TIGR00009 L28: ribosomal protein bL28 2 56 4.0E-23 T 28-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS12465 ff800d87006226f56273220590f91e35 63 Pfam PF00830 Ribosomal L28 family 3 58 3.7E-24 T 28-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS12465 ff800d87006226f56273220590f91e35 63 Gene3D G3DSA:2.30.170.40 2 63 9.7E-24 T 28-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS12465 ff800d87006226f56273220590f91e35 63 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 62 18.951 T 28-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS12465 ff800d87006226f56273220590f91e35 63 SUPERFAMILY SSF143800 2 62 6.28E-26 T 28-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS18085 3ba38bc760e188725825c7bed5a84f09 353 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 17 118 6.9E-22 T 28-03-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CIG75_RS18085 3ba38bc760e188725825c7bed5a84f09 353 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 60 74 4.5E-19 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CIG75_RS18085 3ba38bc760e188725825c7bed5a84f09 353 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 170 190 4.5E-19 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CIG75_RS18085 3ba38bc760e188725825c7bed5a84f09 353 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 126 148 4.5E-19 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CIG75_RS18085 3ba38bc760e188725825c7bed5a84f09 353 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 285 296 4.5E-19 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CIG75_RS18085 3ba38bc760e188725825c7bed5a84f09 353 Gene3D G3DSA:3.40.50.720 138 321 2.2E-28 T 28-03-2018 CIG75_RS18085 3ba38bc760e188725825c7bed5a84f09 353 SUPERFAMILY SSF51735 135 344 3.79E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS18085 3ba38bc760e188725825c7bed5a84f09 353 SMART SM00839 141 350 2.4E-42 T 28-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CIG75_RS18085 3ba38bc760e188725825c7bed5a84f09 353 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 135 292 3.8E-11 T 28-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CIG75_RS18085 3ba38bc760e188725825c7bed5a84f09 353 Gene3D G3DSA:3.40.50.10860 1 137 5.2E-41 T 28-03-2018 CIG75_RS18085 3ba38bc760e188725825c7bed5a84f09 353 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 68 81 - T 28-03-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CIG75_RS18085 3ba38bc760e188725825c7bed5a84f09 353 PIRSF PIRSF000188 1 352 3.8E-139 T 28-03-2018 IPR016211 Glutamate/phenylalanine/leucine/valine dehydrogenase, bacterial/archaeal GO:0016639|GO:0055114 CIG75_RS18085 3ba38bc760e188725825c7bed5a84f09 353 SUPERFAMILY SSF53223 3 138 3.2E-42 T 28-03-2018 CIG75_RS04130 74739c76f3e204d6f2954718aa10b415 429 Gene3D G3DSA:1.25.40.10 135 189 1.3E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS04130 74739c76f3e204d6f2954718aa10b415 429 SUPERFAMILY SSF48452 304 420 3.33E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS04130 74739c76f3e204d6f2954718aa10b415 429 SUPERFAMILY SSF48452 150 342 3.11E-26 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS04130 74739c76f3e204d6f2954718aa10b415 429 Pfam PF13424 Tetratricopeptide repeat 110 168 8.7E-8 T 28-03-2018 CIG75_RS04130 74739c76f3e204d6f2954718aa10b415 429 Gene3D G3DSA:1.10.260.40 2 77 4.1E-15 T 28-03-2018 CIG75_RS04130 74739c76f3e204d6f2954718aa10b415 429 SMART SM00028 230 263 0.0077 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS04130 74739c76f3e204d6f2954718aa10b415 429 SMART SM00028 190 223 0.016 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS04130 74739c76f3e204d6f2954718aa10b415 429 SMART SM00028 108 141 380.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS04130 74739c76f3e204d6f2954718aa10b415 429 SMART SM00028 310 343 67.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS04130 74739c76f3e204d6f2954718aa10b415 429 SMART SM00028 348 381 270.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS04130 74739c76f3e204d6f2954718aa10b415 429 SMART SM00028 148 181 47.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS04130 74739c76f3e204d6f2954718aa10b415 429 Pfam PF01381 Helix-turn-helix 8 61 4.6E-12 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS04130 74739c76f3e204d6f2954718aa10b415 429 SMART SM00530 7 61 4.6E-12 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS04130 74739c76f3e204d6f2954718aa10b415 429 SUPERFAMILY SSF48452 73 178 2.07E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS04130 74739c76f3e204d6f2954718aa10b415 429 Gene3D G3DSA:1.25.40.10 78 134 1.6E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS04130 74739c76f3e204d6f2954718aa10b415 429 Gene3D G3DSA:3.30.70.100 237 271 5.4E-6 T 28-03-2018 CIG75_RS04130 74739c76f3e204d6f2954718aa10b415 429 SUPERFAMILY SSF47413 1 66 5.91E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CIG75_RS04130 74739c76f3e204d6f2954718aa10b415 429 Gene3D G3DSA:1.25.40.10 272 421 1.7E-16 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS04130 74739c76f3e204d6f2954718aa10b415 429 Pfam PF14938 Soluble NSF attachment protein, SNAP 178 330 7.9E-8 T 28-03-2018 CIG75_RS04130 74739c76f3e204d6f2954718aa10b415 429 Gene3D G3DSA:1.10.150.200 190 236 1.4E-10 T 28-03-2018 CIG75_RS19580 725544229869a8cd6c130520f6fdef4e 245 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 2 238 4.4E-62 T 28-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CIG75_RS19580 725544229869a8cd6c130520f6fdef4e 245 Gene3D G3DSA:3.30.70.580 1 105 2.5E-31 T 28-03-2018 CIG75_RS19580 725544229869a8cd6c130520f6fdef4e 245 SUPERFAMILY SSF55120 1 245 8.06E-83 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CIG75_RS19580 725544229869a8cd6c130520f6fdef4e 245 PIRSF PIRSF001430 1 245 6.7E-76 T 28-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CIG75_RS19580 725544229869a8cd6c130520f6fdef4e 245 Pfam PF01416 tRNA pseudouridine synthase 9 103 6.4E-12 T 28-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CIG75_RS19580 725544229869a8cd6c130520f6fdef4e 245 Pfam PF01416 tRNA pseudouridine synthase 143 245 1.6E-30 T 28-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CIG75_RS19580 725544229869a8cd6c130520f6fdef4e 245 Gene3D G3DSA:3.30.70.660 106 243 2.4E-38 T 28-03-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 CIG75_RS19580 725544229869a8cd6c130520f6fdef4e 245 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 2 244 34.954 T 28-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CIG75_RS13105 625583fc5702d409068030282a840a60 165 Pfam PF13799 Domain of unknown function (DUF4183) 93 161 1.2E-12 T 28-03-2018 IPR025237 Domain of unknown function DUF4183 CIG75_RS05350 4afa2f9a3ddda126b892ebb2f306f6eb 317 Pfam PF12671 Putative amidase domain 159 301 6.9E-31 T 28-03-2018 IPR024301 Putative amidase domain CIG75_RS05350 4afa2f9a3ddda126b892ebb2f306f6eb 317 Gene3D G3DSA:3.90.1720.10 151 313 7.4E-13 T 28-03-2018 CIG75_RS10000 0f5267cba9998ecb368851883f44538f 432 TIGRFAM TIGR00457 asnS: asparagine--tRNA ligase 2 431 2.8E-147 T 28-03-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 CIG75_RS10000 0f5267cba9998ecb368851883f44538f 432 Gene3D G3DSA:2.40.50.140 2 102 6.9E-22 T 28-03-2018 CIG75_RS10000 0f5267cba9998ecb368851883f44538f 432 Hamap MF_00534 Asparagine--tRNA ligase [asnS]. 3 432 39.727 T 28-03-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 CIG75_RS10000 0f5267cba9998ecb368851883f44538f 432 SUPERFAMILY SSF55681 97 431 6.43E-90 T 28-03-2018 CIG75_RS10000 0f5267cba9998ecb368851883f44538f 432 Gene3D G3DSA:3.30.930.10 103 432 2.6E-87 T 28-03-2018 CIG75_RS10000 0f5267cba9998ecb368851883f44538f 432 Pfam PF01336 OB-fold nucleic acid binding domain 18 96 6.0E-15 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CIG75_RS10000 0f5267cba9998ecb368851883f44538f 432 PRINTS PR01042 Aspartyl-tRNA synthetase signature 348 364 1.5E-15 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CIG75_RS10000 0f5267cba9998ecb368851883f44538f 432 PRINTS PR01042 Aspartyl-tRNA synthetase signature 183 195 1.5E-15 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CIG75_RS10000 0f5267cba9998ecb368851883f44538f 432 PRINTS PR01042 Aspartyl-tRNA synthetase signature 199 212 1.5E-15 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CIG75_RS10000 0f5267cba9998ecb368851883f44538f 432 PRINTS PR01042 Aspartyl-tRNA synthetase signature 387 401 1.5E-15 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CIG75_RS10000 0f5267cba9998ecb368851883f44538f 432 SUPERFAMILY SSF50249 11 104 6.67E-26 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CIG75_RS10000 0f5267cba9998ecb368851883f44538f 432 Pfam PF00152 tRNA synthetases class II (D, K and N) 113 426 3.7E-82 T 28-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CIG75_RS05280 d8c4136f6acbd171a2222cb178fd143d 189 Gene3D G3DSA:3.40.630.40 5 187 4.7E-35 T 28-03-2018 CIG75_RS05280 d8c4136f6acbd171a2222cb178fd143d 189 SUPERFAMILY SSF53187 8 183 2.83E-35 T 28-03-2018 CIG75_RS05280 d8c4136f6acbd171a2222cb178fd143d 189 SMART SM00646 68 179 1.4E-5 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CIG75_RS05280 d8c4136f6acbd171a2222cb178fd143d 189 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 10 179 1.4E-31 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CIG75_RS01100 723992bc54a65a6c3e840826f237704c 258 SMART SM00422 3 72 4.8E-31 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CIG75_RS01100 723992bc54a65a6c3e840826f237704c 258 Gene3D G3DSA:1.10.1660.10 1 144 2.3E-41 T 28-03-2018 CIG75_RS01100 723992bc54a65a6c3e840826f237704c 258 SUPERFAMILY SSF46955 3 110 5.13E-31 T 28-03-2018 IPR009061 Putative DNA-binding domain CIG75_RS01100 723992bc54a65a6c3e840826f237704c 258 Pfam PF07739 TipAS antibiotic-recognition domain 135 248 1.8E-31 T 28-03-2018 IPR012925 TipAS antibiotic-recognition domain CIG75_RS01100 723992bc54a65a6c3e840826f237704c 258 SUPERFAMILY SSF89082 163 250 5.36E-24 T 28-03-2018 IPR012925 TipAS antibiotic-recognition domain CIG75_RS01100 723992bc54a65a6c3e840826f237704c 258 Pfam PF13411 MerR HTH family regulatory protein 3 71 9.9E-19 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CIG75_RS01100 723992bc54a65a6c3e840826f237704c 258 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 4 15 1.1E-5 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CIG75_RS01100 723992bc54a65a6c3e840826f237704c 258 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 15 28 1.1E-5 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CIG75_RS01100 723992bc54a65a6c3e840826f237704c 258 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 39 59 1.1E-5 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CIG75_RS01100 723992bc54a65a6c3e840826f237704c 258 Gene3D G3DSA:1.10.490.50 158 252 2.0E-24 T 28-03-2018 CIG75_RS17910 d92943c27e769c230ae1222d359385fa 218 Pfam PF01048 Phosphorylase superfamily 37 212 6.1E-20 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CIG75_RS17910 d92943c27e769c230ae1222d359385fa 218 TIGRFAM TIGR03664 fut_nucase: futalosine hydrolase 9 214 5.5E-72 T 28-03-2018 IPR019963 Futalosine hydrolase GO:0009234|GO:0016799 KEGG: 00130+3.2.2.26|MetaCyc: PWY-7374 CIG75_RS17910 d92943c27e769c230ae1222d359385fa 218 SUPERFAMILY SSF53167 8 213 3.14E-34 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CIG75_RS17910 d92943c27e769c230ae1222d359385fa 218 Gene3D G3DSA:3.40.50.1580 1 218 3.0E-43 T 28-03-2018 CIG75_RS17910 d92943c27e769c230ae1222d359385fa 218 Hamap MF_00991 Futalosine hydrolase [mqnB]. 22 216 24.82 T 28-03-2018 IPR019963 Futalosine hydrolase GO:0009234|GO:0016799 KEGG: 00130+3.2.2.26|MetaCyc: PWY-7374 CIG75_RS08400 07299aab9262c67a3b720b7a3207f766 695 Gene3D G3DSA:1.10.10.60 651 695 2.4E-18 T 28-03-2018 CIG75_RS08400 07299aab9262c67a3b720b7a3207f766 695 Gene3D G3DSA:1.10.8.60 541 650 1.7E-17 T 28-03-2018 CIG75_RS08400 07299aab9262c67a3b720b7a3207f766 695 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 454 469 - T 28-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CIG75_RS08400 07299aab9262c67a3b720b7a3207f766 695 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 119 226 1.4E-11 T 28-03-2018 IPR000014 PAS domain CIG75_RS08400 07299aab9262c67a3b720b7a3207f766 695 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 232 348 4.9E-16 T 28-03-2018 IPR000014 PAS domain CIG75_RS08400 07299aab9262c67a3b720b7a3207f766 695 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 391 404 - T 28-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CIG75_RS08400 07299aab9262c67a3b720b7a3207f766 695 Gene3D G3DSA:3.40.50.720 1 102 2.6E-11 T 28-03-2018 CIG75_RS08400 07299aab9262c67a3b720b7a3207f766 695 Pfam PF02954 Bacterial regulatory protein, Fis family 654 692 1.3E-14 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CIG75_RS08400 07299aab9262c67a3b720b7a3207f766 695 SUPERFAMILY SSF55785 106 215 6.28E-18 T 28-03-2018 IPR000014 PAS domain CIG75_RS08400 07299aab9262c67a3b720b7a3207f766 695 SUPERFAMILY SSF52540 366 599 5.58E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS08400 07299aab9262c67a3b720b7a3207f766 695 SUPERFAMILY SSF46689 644 694 2.4E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CIG75_RS08400 07299aab9262c67a3b720b7a3207f766 695 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 581 590 - T 28-03-2018 IPR025944 Sigma-54 interaction domain, conserved site CIG75_RS08400 07299aab9262c67a3b720b7a3207f766 695 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 675 695 2.7E-12 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CIG75_RS08400 07299aab9262c67a3b720b7a3207f766 695 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 658 675 2.7E-12 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CIG75_RS08400 07299aab9262c67a3b720b7a3207f766 695 SUPERFAMILY SSF55785 216 335 1.92E-15 T 28-03-2018 IPR000014 PAS domain CIG75_RS08400 07299aab9262c67a3b720b7a3207f766 695 Gene3D G3DSA:3.30.450.20 227 359 4.8E-19 T 28-03-2018 CIG75_RS08400 07299aab9262c67a3b720b7a3207f766 695 Gene3D G3DSA:3.30.450.20 103 226 4.9E-20 T 28-03-2018 CIG75_RS08400 07299aab9262c67a3b720b7a3207f766 695 SMART SM00382 387 532 4.0E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS08400 07299aab9262c67a3b720b7a3207f766 695 Pfam PF00158 Sigma-54 interaction domain 367 534 1.4E-69 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CIG75_RS08400 07299aab9262c67a3b720b7a3207f766 695 Gene3D G3DSA:3.40.50.300 362 540 5.7E-26 T 28-03-2018 CIG75_RS08400 07299aab9262c67a3b720b7a3207f766 695 SMART SM00091 235 300 6.0E-6 T 28-03-2018 IPR000014 PAS domain CIG75_RS08400 07299aab9262c67a3b720b7a3207f766 695 SMART SM00091 117 183 6.5E-8 T 28-03-2018 IPR000014 PAS domain CIG75_RS08400 07299aab9262c67a3b720b7a3207f766 695 Pfam PF00989 PAS fold 122 217 4.2E-12 T 28-03-2018 IPR013767 PAS fold GO:0006355 CIG75_RS08400 07299aab9262c67a3b720b7a3207f766 695 Pfam PF00989 PAS fold 236 338 1.9E-10 T 28-03-2018 IPR013767 PAS fold GO:0006355 CIG75_RS08400 07299aab9262c67a3b720b7a3207f766 695 SUPERFAMILY SSF51735 2 101 2.25E-13 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS10400 3b33c6e950618ef90ec285c384ceea1a 552 Gene3D G3DSA:3.30.70.270 381 552 2.3E-58 T 28-03-2018 CIG75_RS10400 3b33c6e950618ef90ec285c384ceea1a 552 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 377 545 8.6E-50 T 28-03-2018 IPR000160 GGDEF domain CIG75_RS10400 3b33c6e950618ef90ec285c384ceea1a 552 Gene3D G3DSA:3.30.450.40 244 380 3.7E-6 T 28-03-2018 IPR029016 GAF domain-like CIG75_RS10400 3b33c6e950618ef90ec285c384ceea1a 552 SUPERFAMILY SSF55781 247 380 9.81E-7 T 28-03-2018 IPR029016 GAF domain-like CIG75_RS10400 3b33c6e950618ef90ec285c384ceea1a 552 SUPERFAMILY SSF55073 386 548 4.0E-46 T 28-03-2018 IPR029787 Nucleotide cyclase CIG75_RS10400 3b33c6e950618ef90ec285c384ceea1a 552 SMART SM00267 370 546 1.4E-56 T 28-03-2018 IPR000160 GGDEF domain CIG75_RS10400 3b33c6e950618ef90ec285c384ceea1a 552 Pfam PF00990 Diguanylate cyclase, GGDEF domain 382 542 5.7E-47 T 28-03-2018 IPR000160 GGDEF domain CIG75_RS07720 4c5cef75afc901b6e0f99a1e18f0fa4c 417 SUPERFAMILY SSF53633 3 242 9.16E-76 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CIG75_RS07720 4c5cef75afc901b6e0f99a1e18f0fa4c 417 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 63 401 1.8E-118 T 28-03-2018 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CIG75_RS07720 4c5cef75afc901b6e0f99a1e18f0fa4c 417 Gene3D G3DSA:3.30.70.260 330 402 8.2E-20 T 28-03-2018 CIG75_RS07720 4c5cef75afc901b6e0f99a1e18f0fa4c 417 Gene3D G3DSA:3.30.70.260 235 329 8.7E-20 T 28-03-2018 CIG75_RS07720 4c5cef75afc901b6e0f99a1e18f0fa4c 417 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 28-03-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CIG75_RS07720 4c5cef75afc901b6e0f99a1e18f0fa4c 417 SUPERFAMILY SSF55021 333 405 7.13E-23 T 28-03-2018 CIG75_RS07720 4c5cef75afc901b6e0f99a1e18f0fa4c 417 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 2 400 1.3E-138 T 28-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CIG75_RS07720 4c5cef75afc901b6e0f99a1e18f0fa4c 417 SUPERFAMILY SSF55021 249 323 6.74E-15 T 28-03-2018 CIG75_RS07720 4c5cef75afc901b6e0f99a1e18f0fa4c 417 Gene3D G3DSA:3.40.1160.10 1 234 1.1E-71 T 28-03-2018 CIG75_RS07720 4c5cef75afc901b6e0f99a1e18f0fa4c 417 Pfam PF00696 Amino acid kinase family 3 229 1.5E-57 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CIG75_RS07720 4c5cef75afc901b6e0f99a1e18f0fa4c 417 Pfam PF13840 ACT domain 335 397 3.7E-16 T 28-03-2018 IPR027795 GATS-like ACT domain CIG75_RS07720 4c5cef75afc901b6e0f99a1e18f0fa4c 417 PIRSF PIRSF000726 1 62 5.7E-19 T 28-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CIG75_RS07720 4c5cef75afc901b6e0f99a1e18f0fa4c 417 PIRSF PIRSF000726 56 408 5.5E-125 T 28-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CIG75_RS13710 e485d0ff3cbf122cc1ac483460d1acc5 708 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 556 674 1.1E-17 T 28-03-2018 IPR000160 GGDEF domain CIG75_RS13710 e485d0ff3cbf122cc1ac483460d1acc5 708 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 380 547 2.6E-42 T 28-03-2018 IPR000160 GGDEF domain CIG75_RS13710 e485d0ff3cbf122cc1ac483460d1acc5 708 SUPERFAMILY SSF55781 251 384 7.2E-15 T 28-03-2018 IPR029016 GAF domain-like CIG75_RS13710 e485d0ff3cbf122cc1ac483460d1acc5 708 SMART SM00065 247 381 2.5E-6 T 28-03-2018 IPR003018 GAF domain GO:0005515 CIG75_RS13710 e485d0ff3cbf122cc1ac483460d1acc5 708 Gene3D G3DSA:3.30.70.270 383 553 1.6E-47 T 28-03-2018 CIG75_RS13710 e485d0ff3cbf122cc1ac483460d1acc5 708 Gene3D G3DSA:3.30.70.270 554 698 1.5E-25 T 28-03-2018 CIG75_RS13710 e485d0ff3cbf122cc1ac483460d1acc5 708 Pfam PF13185 GAF domain 251 372 5.5E-8 T 28-03-2018 IPR003018 GAF domain GO:0005515 CIG75_RS13710 e485d0ff3cbf122cc1ac483460d1acc5 708 SUPERFAMILY SSF55073 389 549 2.43E-38 T 28-03-2018 IPR029787 Nucleotide cyclase CIG75_RS13710 e485d0ff3cbf122cc1ac483460d1acc5 708 SMART SM00267 373 548 1.9E-40 T 28-03-2018 IPR000160 GGDEF domain CIG75_RS13710 e485d0ff3cbf122cc1ac483460d1acc5 708 SMART SM00267 549 704 1.2E-6 T 28-03-2018 IPR000160 GGDEF domain CIG75_RS13710 e485d0ff3cbf122cc1ac483460d1acc5 708 Gene3D G3DSA:3.30.450.40 248 382 2.0E-16 T 28-03-2018 IPR029016 GAF domain-like CIG75_RS13710 e485d0ff3cbf122cc1ac483460d1acc5 708 Pfam PF00990 Diguanylate cyclase, GGDEF domain 387 544 7.6E-36 T 28-03-2018 IPR000160 GGDEF domain CIG75_RS13710 e485d0ff3cbf122cc1ac483460d1acc5 708 Pfam PF00990 Diguanylate cyclase, GGDEF domain 558 681 1.1E-19 T 28-03-2018 IPR000160 GGDEF domain CIG75_RS13710 e485d0ff3cbf122cc1ac483460d1acc5 708 SUPERFAMILY SSF55073 561 676 1.88E-19 T 28-03-2018 IPR029787 Nucleotide cyclase CIG75_RS11605 3d2eca86eeb74cfd4002b2ed0e7fd5f3 163 SUPERFAMILY SSF89963 92 163 1.03E-30 T 28-03-2018 IPR007551 Protein of unknown function DUF520 CIG75_RS11605 3d2eca86eeb74cfd4002b2ed0e7fd5f3 163 Gene3D G3DSA:3.30.70.990 13 98 1.9E-32 T 28-03-2018 IPR035570 UPF0234 N-terminal domain CIG75_RS11605 3d2eca86eeb74cfd4002b2ed0e7fd5f3 163 Gene3D G3DSA:3.30.70.860 99 163 1.1E-33 T 28-03-2018 IPR035571 UPF0234/UPF0381 domain CIG75_RS11605 3d2eca86eeb74cfd4002b2ed0e7fd5f3 163 SUPERFAMILY SSF89963 6 88 3.01E-29 T 28-03-2018 IPR007551 Protein of unknown function DUF520 CIG75_RS11605 3d2eca86eeb74cfd4002b2ed0e7fd5f3 163 Pfam PF04461 Protein of unknown function (DUF520) 6 163 1.2E-67 T 28-03-2018 IPR007551 Protein of unknown function DUF520 CIG75_RS11605 3d2eca86eeb74cfd4002b2ed0e7fd5f3 163 Hamap MF_00632 UPF0234 protein YajQ [yajQ]. 4 163 28.404 T 28-03-2018 IPR007551 Protein of unknown function DUF520 CIG75_RS15650 0663619502e56ad41d7cdcaae805775e 465 SUPERFAMILY SSF53383 3 457 3.69E-145 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CIG75_RS15650 0663619502e56ad41d7cdcaae805775e 465 ProSitePatterns PS00853 Beta-eliminating lyases pyridoxal-phosphate attachment site. 247 265 - T 28-03-2018 IPR018176 Tryptophanase, conserved site KEGG: 00380+4.1.99.1 CIG75_RS15650 0663619502e56ad41d7cdcaae805775e 465 PIRSF PIRSF001386 1 458 1.0E-225 T 28-03-2018 IPR011166 Beta-eliminating lyase family GO:0009072|GO:0016830 KEGG: 00380+4.1.99.1 CIG75_RS15650 0663619502e56ad41d7cdcaae805775e 465 Hamap MF_00544 Tryptophanase [tnaA]. 1 457 102.213 T 28-03-2018 IPR013440 Tryptophanase GO:0006568|GO:0009034 KEGG: 00380+4.1.99.1 CIG75_RS15650 0663619502e56ad41d7cdcaae805775e 465 Gene3D G3DSA:3.90.1150.10 273 455 1.7E-75 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CIG75_RS15650 0663619502e56ad41d7cdcaae805775e 465 Gene3D G3DSA:3.90.1150.10 16 152 2.1E-29 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CIG75_RS15650 0663619502e56ad41d7cdcaae805775e 465 Pfam PF01212 Beta-eliminating lyase 45 422 1.2E-96 T 28-03-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 CIG75_RS07810 c4ca6092ea472796812e9046f61287dc 202 Hamap MF_01405 dITP/XTP pyrophosphatase [rdgB]. 6 197 45.109 T 28-03-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 CIG75_RS07810 c4ca6092ea472796812e9046f61287dc 202 Gene3D G3DSA:3.90.950.10 1 200 7.1E-75 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CIG75_RS07810 c4ca6092ea472796812e9046f61287dc 202 Pfam PF01725 Ham1 family 8 193 1.1E-56 T 28-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 CIG75_RS07810 c4ca6092ea472796812e9046f61287dc 202 SUPERFAMILY SSF52972 5 196 2.3E-65 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CIG75_RS07810 c4ca6092ea472796812e9046f61287dc 202 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 7 195 1.4E-55 T 28-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 CIG75_RS09300 2539999077f8916bc15f47fd4e692a13 386 PIRSF PIRSF001434 1 386 4.7E-140 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CIG75_RS09300 2539999077f8916bc15f47fd4e692a13 386 Gene3D G3DSA:3.40.640.10 7 251 9.5E-57 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CIG75_RS09300 2539999077f8916bc15f47fd4e692a13 386 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 193 207 - T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CIG75_RS09300 2539999077f8916bc15f47fd4e692a13 386 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 10 382 2.4E-144 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CIG75_RS09300 2539999077f8916bc15f47fd4e692a13 386 Gene3D G3DSA:3.90.1150.10 253 386 4.2E-44 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CIG75_RS09300 2539999077f8916bc15f47fd4e692a13 386 SUPERFAMILY SSF53383 13 382 5.3E-113 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CIG75_RS08155 c74b60d3932066ebcf721676a9103dfe 348 SUPERFAMILY SSF141986 199 338 1.07E-25 T 28-03-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain CIG75_RS08155 c74b60d3932066ebcf721676a9103dfe 348 Gene3D G3DSA:3.50.30.60 170 348 1.9E-40 T 28-03-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain CIG75_RS08155 c74b60d3932066ebcf721676a9103dfe 348 Pfam PF02016 LD-carboxypeptidase 17 334 1.7E-67 T 28-03-2018 IPR003507 Peptidase family S66 CIG75_RS08155 c74b60d3932066ebcf721676a9103dfe 348 SUPERFAMILY SSF52317 5 167 1.92E-36 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CIG75_RS08155 c74b60d3932066ebcf721676a9103dfe 348 Gene3D G3DSA:3.40.50.10740 1 169 5.1E-38 T 28-03-2018 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal domain CIG75_RS08155 c74b60d3932066ebcf721676a9103dfe 348 PIRSF PIRSF028757 5 347 2.1E-56 T 28-03-2018 IPR003507 Peptidase family S66 CIG75_RS14230 b4718f6f22b5e619167e2fb31a0ac917 324 SMART SM00283 132 314 8.4E-4 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CIG75_RS14230 b4718f6f22b5e619167e2fb31a0ac917 324 Pfam PF11563 Protoglobin 8 156 6.6E-33 T 28-03-2018 CIG75_RS14230 b4718f6f22b5e619167e2fb31a0ac917 324 Gene3D G3DSA:1.10.490.10 3 148 1.7E-27 T 28-03-2018 CIG75_RS14230 b4718f6f22b5e619167e2fb31a0ac917 324 SUPERFAMILY SSF58104 157 315 1.83E-37 T 28-03-2018 CIG75_RS14230 b4718f6f22b5e619167e2fb31a0ac917 324 Gene3D G3DSA:1.10.287.950 149 324 9.9E-33 T 28-03-2018 CIG75_RS14230 b4718f6f22b5e619167e2fb31a0ac917 324 SUPERFAMILY SSF46458 8 147 5.55E-32 T 28-03-2018 IPR009050 Globin-like CIG75_RS14230 b4718f6f22b5e619167e2fb31a0ac917 324 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 186 322 5.7E-25 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CIG75_RS14565 967b8903e2e8c510993a3b0067a69c1a 74 SUPERFAMILY SSF55008 16 66 4.49E-6 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CIG75_RS14565 967b8903e2e8c510993a3b0067a69c1a 74 Gene3D G3DSA:3.30.70.100 13 69 7.4E-5 T 28-03-2018 CIG75_RS07805 6883a77853f99173220ea1e4e88ec7b4 252 Pfam PF01138 3' exoribonuclease family, domain 1 10 140 3.6E-25 T 28-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CIG75_RS07805 6883a77853f99173220ea1e4e88ec7b4 252 Pfam PF03725 3' exoribonuclease family, domain 2 159 222 8.9E-14 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CIG75_RS07805 6883a77853f99173220ea1e4e88ec7b4 252 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 2 236 1.1E-114 T 28-03-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 CIG75_RS07805 6883a77853f99173220ea1e4e88ec7b4 252 ProSitePatterns PS01277 Ribonuclease PH signature. 116 128 - T 28-03-2018 IPR018336 Ribonuclease PH, conserved site CIG75_RS07805 6883a77853f99173220ea1e4e88ec7b4 252 Hamap MF_00564 Ribonuclease PH [rph]. 1 237 47.511 T 28-03-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 CIG75_RS07805 6883a77853f99173220ea1e4e88ec7b4 252 SUPERFAMILY SSF55666 154 238 2.75E-23 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CIG75_RS07805 6883a77853f99173220ea1e4e88ec7b4 252 SUPERFAMILY SSF54211 1 181 9.11E-47 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CIG75_RS07805 6883a77853f99173220ea1e4e88ec7b4 252 Gene3D G3DSA:3.30.230.70 1 239 2.5E-60 T 28-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CIG75_RS12990 7c718351482713e1e6dc1eba5a3dc130 397 SUPERFAMILY SSF48452 112 326 2.54E-21 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS12990 7c718351482713e1e6dc1eba5a3dc130 397 Gene3D G3DSA:1.25.40.10 135 185 2.3E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS12990 7c718351482713e1e6dc1eba5a3dc130 397 Gene3D G3DSA:1.25.40.10 186 224 4.8E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS12990 7c718351482713e1e6dc1eba5a3dc130 397 Gene3D G3DSA:1.10.10.60 8 49 1.2E-6 T 28-03-2018 CIG75_RS12990 7c718351482713e1e6dc1eba5a3dc130 397 SMART SM00028 133 166 96.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS12990 7c718351482713e1e6dc1eba5a3dc130 397 SMART SM00028 210 243 0.82 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS12990 7c718351482713e1e6dc1eba5a3dc130 397 SMART SM00028 364 397 98.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS12990 7c718351482713e1e6dc1eba5a3dc130 397 SMART SM00028 250 283 0.0032 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS12990 7c718351482713e1e6dc1eba5a3dc130 397 Gene3D G3DSA:1.25.20.10 288 395 4.0E-4 T 28-03-2018 CIG75_RS12990 7c718351482713e1e6dc1eba5a3dc130 397 Gene3D G3DSA:3.30.1190.10 50 134 6.3E-6 T 28-03-2018 CIG75_RS12990 7c718351482713e1e6dc1eba5a3dc130 397 Gene3D G3DSA:1.25.40.10 225 287 4.8E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS12990 7c718351482713e1e6dc1eba5a3dc130 397 SUPERFAMILY SSF47413 24 89 9.29E-10 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CIG75_RS12990 7c718351482713e1e6dc1eba5a3dc130 397 SMART SM00530 29 86 6.5E-8 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS12990 7c718351482713e1e6dc1eba5a3dc130 397 Pfam PF13424 Tetratricopeptide repeat 176 235 3.1E-9 T 28-03-2018 CIG75_RS12990 7c718351482713e1e6dc1eba5a3dc130 397 Pfam PF13424 Tetratricopeptide repeat 255 316 1.5E-7 T 28-03-2018 CIG75_RS12990 7c718351482713e1e6dc1eba5a3dc130 397 Pfam PF01381 Helix-turn-helix 34 84 4.8E-8 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS03280 8bdf229fd0074e31d83486da0318e8d6 210 SUPERFAMILY SSF46894 137 209 6.12E-24 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CIG75_RS03280 8bdf229fd0074e31d83486da0318e8d6 210 Gene3D G3DSA:1.10.10.10 134 208 6.0E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS03280 8bdf229fd0074e31d83486da0318e8d6 210 SMART SM00448 2 115 1.2E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CIG75_RS03280 8bdf229fd0074e31d83486da0318e8d6 210 SMART SM00421 146 203 2.4E-27 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CIG75_RS03280 8bdf229fd0074e31d83486da0318e8d6 210 Gene3D G3DSA:3.40.50.2300 1 133 1.6E-37 T 28-03-2018 CIG75_RS03280 8bdf229fd0074e31d83486da0318e8d6 210 SUPERFAMILY SSF52172 1 132 4.13E-34 T 28-03-2018 IPR011006 CheY-like superfamily CIG75_RS03280 8bdf229fd0074e31d83486da0318e8d6 210 Pfam PF00196 Bacterial regulatory proteins, luxR family 148 203 3.4E-22 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CIG75_RS03280 8bdf229fd0074e31d83486da0318e8d6 210 Pfam PF00072 Response regulator receiver domain 4 116 1.5E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CIG75_RS03280 8bdf229fd0074e31d83486da0318e8d6 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 179 1.5E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CIG75_RS03280 8bdf229fd0074e31d83486da0318e8d6 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 191 1.5E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CIG75_RS03280 8bdf229fd0074e31d83486da0318e8d6 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 163 1.5E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CIG75_RS05215 53f794e882ed202ec69490e650c4c8d9 116 Pfam PF07883 Cupin domain 37 104 8.9E-7 T 28-03-2018 IPR013096 Cupin 2, conserved barrel CIG75_RS05215 53f794e882ed202ec69490e650c4c8d9 116 Gene3D G3DSA:2.60.120.10 3 113 4.4E-13 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CIG75_RS05215 53f794e882ed202ec69490e650c4c8d9 116 SUPERFAMILY SSF51182 18 112 8.25E-15 T 28-03-2018 IPR011051 RmlC-like cupin domain CIG75_RS08570 292b3456b02d843a22c65a8e36422ae7 295 Gene3D G3DSA:1.10.150.130 1 109 1.1E-23 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CIG75_RS08570 292b3456b02d843a22c65a8e36422ae7 295 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 3 295 59.625 T 28-03-2018 IPR023009 Tyrosine recombinase XerC/XerD CIG75_RS08570 292b3456b02d843a22c65a8e36422ae7 295 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 5 87 5.4E-21 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CIG75_RS08570 292b3456b02d843a22c65a8e36422ae7 295 Hamap MF_01807 Tyrosine recombinase XerD [xerD]. 1 295 61.105 T 28-03-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 CIG75_RS08570 292b3456b02d843a22c65a8e36422ae7 295 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 6 295 1.9E-119 T 28-03-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 CIG75_RS08570 292b3456b02d843a22c65a8e36422ae7 295 Pfam PF00589 Phage integrase family 109 281 8.4E-52 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CIG75_RS08570 292b3456b02d843a22c65a8e36422ae7 295 SUPERFAMILY SSF56349 3 288 1.5E-58 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CIG75_RS08570 292b3456b02d843a22c65a8e36422ae7 295 Gene3D G3DSA:1.10.443.10 110 289 1.8E-48 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CIG75_RS01560 ed515047ae7901f3ddadf7b694817948 258 Gene3D G3DSA:3.30.30.60 30 79 6.9E-23 T 28-03-2018 IPR028991 D-lysine 5,6-aminomutase beta subunit KamE, N-terminal GO:0046983 CIG75_RS01560 ed515047ae7901f3ddadf7b694817948 258 Pfam PF16554 Dimerisation domain of d-ornithine 4,5-aminomutase 17 94 8.4E-31 T 28-03-2018 IPR028991 D-lysine 5,6-aminomutase beta subunit KamE, N-terminal GO:0046983 CIG75_RS01560 ed515047ae7901f3ddadf7b694817948 258 SUPERFAMILY SSF117778 29 79 2.09E-17 T 28-03-2018 IPR028991 D-lysine 5,6-aminomutase beta subunit KamE, N-terminal GO:0046983 CIG75_RS01560 ed515047ae7901f3ddadf7b694817948 258 Pfam PF02310 B12 binding domain 118 241 4.3E-20 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CIG75_RS01560 ed515047ae7901f3ddadf7b694817948 258 SUPERFAMILY SSF52242 102 255 2.88E-43 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CIG75_RS01560 ed515047ae7901f3ddadf7b694817948 258 Gene3D G3DSA:3.40.50.280 106 255 2.6E-42 T 28-03-2018 CIG75_RS02510 1f0e181d9ed0c68d6efc32eba5a38997 245 Gene3D G3DSA:3.40.1700.10 86 214 5.8E-35 T 28-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal CIG75_RS02510 1f0e181d9ed0c68d6efc32eba5a38997 245 Hamap MF_01499 Diadenylate cyclase [dacA]. 1 229 30.486 T 28-03-2018 IPR034701 Diadenylate cyclase CdaA GO:0004016|GO:0006171 CIG75_RS02510 1f0e181d9ed0c68d6efc32eba5a38997 245 SUPERFAMILY SSF143597 13 216 6.8E-68 T 28-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal CIG75_RS02510 1f0e181d9ed0c68d6efc32eba5a38997 245 TIGRFAM TIGR00159 TIGR00159: TIGR00159 family protein 4 231 6.9E-81 T 28-03-2018 IPR034701 Diadenylate cyclase CdaA GO:0004016|GO:0006171 CIG75_RS02510 1f0e181d9ed0c68d6efc32eba5a38997 245 PIRSF PIRSF004793 1 238 7.6E-85 T 28-03-2018 IPR014046 Diadenylate cyclase GO:0004016|GO:0006171 CIG75_RS02510 1f0e181d9ed0c68d6efc32eba5a38997 245 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 93 210 3.0E-42 T 28-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal CIG75_RS01025 7e0c456cb22e62b0f68b6e94b56a8bf5 317 Pfam PF01032 FecCD transport family 10 311 2.1E-68 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CIG75_RS01025 7e0c456cb22e62b0f68b6e94b56a8bf5 317 SUPERFAMILY SSF81345 3 312 2.22E-71 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CIG75_RS01025 7e0c456cb22e62b0f68b6e94b56a8bf5 317 Gene3D G3DSA:1.10.3470.10 2 317 2.1E-45 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 SMART SM00823 Phosphopantetheine attachment site 3959 4028 1.9E-4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 SMART SM00823 Phosphopantetheine attachment site 1814 1886 0.37 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 SMART SM00823 Phosphopantetheine attachment site 770 839 0.0081 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 SUPERFAMILY SSF47336 2882 2952 4.19E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 SUPERFAMILY SSF47336 1809 1878 4.06E-17 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 Pfam PF00550 Phosphopantetheine attachment site 772 834 2.3E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 Pfam PF00550 Phosphopantetheine attachment site 3961 4023 1.1E-8 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 Pfam PF00550 Phosphopantetheine attachment site 2892 2951 2.3E-10 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 Pfam PF00550 Phosphopantetheine attachment site 1820 1879 7.6E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2392 2803 9.7E-140 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 3468 3872 2.0E-142 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 291 685 3.8E-140 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1341 1735 9.7E-142 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 ProSitePatterns PS00455 Putative AMP-binding domain signature. 412 423 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 ProSitePatterns PS00455 Putative AMP-binding domain signature. 3591 3602 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 SUPERFAMILY SSF52777 12 233 7.89E-32 T 28-03-2018 CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1841 1856 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 SUPERFAMILY SSF47336 766 835 5.76E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 Gene3D G3DSA:3.30.300.30 656 775 9.6E-36 T 28-03-2018 CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 Gene3D G3DSA:3.30.300.30 1706 1823 5.4E-36 T 28-03-2018 CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 Gene3D G3DSA:3.30.300.30 3843 3966 8.9E-41 T 28-03-2018 CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 Gene3D G3DSA:3.30.300.30 2774 2896 3.7E-38 T 28-03-2018 CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 SUPERFAMILY SSF52777 1040 1304 6.34E-69 T 28-03-2018 CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 ProSitePatterns PS00012 Phosphopantetheine attachment site. 794 809 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 Pfam PF13193 AMP-binding enzyme C-terminal domain 1719 1788 1.4E-10 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 Pfam PF13193 AMP-binding enzyme C-terminal domain 2787 2862 3.3E-14 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 Pfam PF13193 AMP-binding enzyme C-terminal domain 3856 3931 1.2E-10 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 Pfam PF13193 AMP-binding enzyme C-terminal domain 669 743 1.8E-12 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 SUPERFAMILY SSF52777 1908 2086 3.56E-50 T 28-03-2018 CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 Pfam PF00501 AMP-binding enzyme 3446 3848 8.3E-108 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 Pfam PF00501 AMP-binding enzyme 270 661 1.1E-99 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 Pfam PF00501 AMP-binding enzyme 2371 2779 8.4E-109 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 Pfam PF00501 AMP-binding enzyme 1320 1711 3.7E-99 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1462 1473 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 Gene3D G3DSA:1.10.1200.10 3967 4036 1.0E-19 T 28-03-2018 CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 Gene3D G3DSA:1.10.1200.10 776 840 2.8E-18 T 28-03-2018 CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 Gene3D G3DSA:3.40.50.980 2519 2682 2.6E-40 T 28-03-2018 CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 Gene3D G3DSA:3.40.50.980 3597 3756 4.6E-41 T 28-03-2018 CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 Gene3D G3DSA:3.40.50.980 1468 1619 2.5E-36 T 28-03-2018 CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 Gene3D G3DSA:3.40.50.980 419 569 5.7E-29 T 28-03-2018 CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 SUPERFAMILY SSF56801 226 783 7.2E-158 T 28-03-2018 CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 Gene3D G3DSA:3.40.50.980 3437 3596 1.7E-48 T 28-03-2018 CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 Gene3D G3DSA:3.40.50.980 1312 1467 1.1E-46 T 28-03-2018 CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 Gene3D G3DSA:3.40.50.980 261 418 2.9E-49 T 28-03-2018 CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 Gene3D G3DSA:3.40.50.980 2362 2518 5.1E-48 T 28-03-2018 CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 Gene3D G3DSA:2.30.38.10 1622 1704 9.3E-24 T 28-03-2018 CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 SUPERFAMILY SSF52777 3173 3432 6.34E-40 T 28-03-2018 CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 Gene3D G3DSA:3.30.559.10 1884 2108 5.0E-48 T 28-03-2018 CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 Gene3D G3DSA:3.30.559.10 841 1055 1.5E-45 T 28-03-2018 CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 Gene3D G3DSA:2.30.38.10 2688 2772 9.0E-24 T 28-03-2018 CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 Gene3D G3DSA:2.30.38.10 3757 3841 7.0E-24 T 28-03-2018 CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 Gene3D G3DSA:2.30.38.10 570 654 2.6E-24 T 28-03-2018 CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 SUPERFAMILY SSF56801 2329 2903 1.96E-170 T 28-03-2018 CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 SUPERFAMILY SSF56801 3415 3970 4.45E-171 T 28-03-2018 CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 SUPERFAMILY SSF52777 2981 3185 3.71E-38 T 28-03-2018 CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2914 2929 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 Gene3D G3DSA:1.10.1200.10 1824 1879 2.3E-16 T 28-03-2018 CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 Gene3D G3DSA:1.10.1200.10 2897 2952 7.7E-14 T 28-03-2018 CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 SUPERFAMILY SSF52777 857 1033 2.52E-49 T 28-03-2018 CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2513 2524 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 Pfam PF00668 Condensation domain 6 249 2.3E-23 T 28-03-2018 IPR001242 Condensation domain CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 Pfam PF00668 Condensation domain 854 1300 1.3E-123 T 28-03-2018 IPR001242 Condensation domain CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 Pfam PF00668 Condensation domain 1904 2351 4.6E-120 T 28-03-2018 IPR001242 Condensation domain CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 Pfam PF00668 Condensation domain 2985 3425 6.7E-71 T 28-03-2018 IPR001242 Condensation domain CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 SUPERFAMILY SSF56801 1280 1830 4.32E-159 T 28-03-2018 CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 SUPERFAMILY SSF52777 2094 2339 1.22E-67 T 28-03-2018 CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 SUPERFAMILY SSF47336 3951 4024 2.49E-18 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10645 b911b388cc5bd470014a4513eb94c3ef 4077 Gene3D G3DSA:3.30.559.10 2970 3170 4.7E-30 T 28-03-2018 CIG75_RS14830 82d25f6fe487b636f923378757812ffb 360 PIRSF PIRSF038991 1 359 1.7E-84 T 28-03-2018 IPR007820 AbrB family GO:0010468|GO:0016021 CIG75_RS14830 82d25f6fe487b636f923378757812ffb 360 TIGRFAM TIGR03082 Gneg_AbrB_dup: membrane protein AbrB duplication 13 163 2.6E-37 T 28-03-2018 IPR017516 AbrB duplication CIG75_RS14830 82d25f6fe487b636f923378757812ffb 360 TIGRFAM TIGR03082 Gneg_AbrB_dup: membrane protein AbrB duplication 195 351 2.3E-37 T 28-03-2018 IPR017516 AbrB duplication CIG75_RS14830 82d25f6fe487b636f923378757812ffb 360 Pfam PF05145 Transition state regulatory protein AbrB 32 351 1.7E-79 T 28-03-2018 IPR007820 AbrB family GO:0010468|GO:0016021 CIG75_RS20160 a8ab5396526b9f04240b14d622cce578 717 SUPERFAMILY SSF56300 210 501 8.26E-76 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CIG75_RS20160 a8ab5396526b9f04240b14d622cce578 717 ProSitePatterns PS00786 5'-nucleotidase signature 2. 287 298 - T 28-03-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CIG75_RS20160 a8ab5396526b9f04240b14d622cce578 717 Gene3D G3DSA:3.60.21.10 208 525 5.3E-73 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CIG75_RS20160 a8ab5396526b9f04240b14d622cce578 717 Pfam PF00149 Calcineurin-like phosphoesterase 212 434 5.7E-10 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CIG75_RS20160 a8ab5396526b9f04240b14d622cce578 717 Pfam PF00395 S-layer homology domain 156 199 3.3E-8 T 28-03-2018 IPR001119 S-layer homology domain CIG75_RS20160 a8ab5396526b9f04240b14d622cce578 717 Pfam PF00395 S-layer homology domain 98 133 6.6E-8 T 28-03-2018 IPR001119 S-layer homology domain CIG75_RS20160 a8ab5396526b9f04240b14d622cce578 717 PRINTS PR01607 Apyrase family signature 443 463 9.5E-20 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CIG75_RS20160 a8ab5396526b9f04240b14d622cce578 717 PRINTS PR01607 Apyrase family signature 417 440 9.5E-20 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CIG75_RS20160 a8ab5396526b9f04240b14d622cce578 717 PRINTS PR01607 Apyrase family signature 569 592 9.5E-20 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CIG75_RS20160 a8ab5396526b9f04240b14d622cce578 717 PRINTS PR01607 Apyrase family signature 646 665 9.5E-20 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CIG75_RS20160 a8ab5396526b9f04240b14d622cce578 717 PRINTS PR01607 Apyrase family signature 386 403 9.5E-20 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CIG75_RS20160 a8ab5396526b9f04240b14d622cce578 717 PRINTS PR01607 Apyrase family signature 208 226 9.5E-20 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CIG75_RS20160 a8ab5396526b9f04240b14d622cce578 717 Gene3D G3DSA:3.90.780.10 526 709 9.0E-34 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CIG75_RS20160 a8ab5396526b9f04240b14d622cce578 717 SUPERFAMILY SSF55816 527 709 4.45E-32 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CIG75_RS20160 a8ab5396526b9f04240b14d622cce578 717 Pfam PF02872 5'-nucleotidase, C-terminal domain 530 672 2.1E-27 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CIG75_RS14345 e7709c5470f779258d0df2ab648d37af 467 Gene3D G3DSA:3.90.640.20 161 253 2.3E-15 T 28-03-2018 IPR021729 Domain of unknown function DUF3298 CIG75_RS14345 e7709c5470f779258d0df2ab648d37af 467 Pfam PF01522 Polysaccharide deacetylase 282 398 3.9E-34 T 28-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CIG75_RS14345 e7709c5470f779258d0df2ab648d37af 467 Pfam PF11738 Protein of unknown function (DUF3298) 191 239 1.1E-8 T 28-03-2018 IPR021729 Domain of unknown function DUF3298 CIG75_RS14345 e7709c5470f779258d0df2ab648d37af 467 Gene3D G3DSA:3.30.565.40 54 159 1.9E-11 T 28-03-2018 CIG75_RS14345 e7709c5470f779258d0df2ab648d37af 467 SUPERFAMILY SSF88713 272 466 7.69E-61 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CIG75_RS14345 e7709c5470f779258d0df2ab648d37af 467 Gene3D G3DSA:3.20.20.370 254 467 5.2E-53 T 28-03-2018 CIG75_RS10915 ece174f8bc65cf6c0b7df554c00bf00b 365 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 13 358 7.2E-114 T 28-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CIG75_RS10915 ece174f8bc65cf6c0b7df554c00bf00b 365 Gene3D G3DSA:3.40.50.1970 4 175 1.5E-48 T 28-03-2018 CIG75_RS10915 ece174f8bc65cf6c0b7df554c00bf00b 365 Gene3D G3DSA:1.20.1090.10 176 365 2.0E-68 T 28-03-2018 CIG75_RS10915 ece174f8bc65cf6c0b7df554c00bf00b 365 SUPERFAMILY SSF56796 6 359 2.09E-106 T 28-03-2018 CIG75_RS10915 ece174f8bc65cf6c0b7df554c00bf00b 365 Pfam PF01761 3-dehydroquinate synthase 71 328 4.2E-98 T 28-03-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CIG75_RS10915 ece174f8bc65cf6c0b7df554c00bf00b 365 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 2 361 39.314 T 28-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CIG75_RS10915 ece174f8bc65cf6c0b7df554c00bf00b 365 PIRSF PIRSF001455 4 364 2.5E-106 T 28-03-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CIG75_RS20105 450eaded26eb5db7ddcc75d30d626d73 395 Gene3D G3DSA:3.20.20.20 116 395 1.7E-113 T 28-03-2018 CIG75_RS20105 450eaded26eb5db7ddcc75d30d626d73 395 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 178 191 - T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CIG75_RS20105 450eaded26eb5db7ddcc75d30d626d73 395 SUPERFAMILY SSF51717 133 395 3.53E-104 T 28-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CIG75_RS20105 450eaded26eb5db7ddcc75d30d626d73 395 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 144 393 1.2E-99 T 28-03-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 CIG75_RS20105 450eaded26eb5db7ddcc75d30d626d73 395 Pfam PF00809 Pterin binding enzyme 145 378 3.5E-89 T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CIG75_RS20105 450eaded26eb5db7ddcc75d30d626d73 395 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 144 159 - T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CIG75_RS17365 fecc23b2a96b8903f71bb0e8838da385 308 SUPERFAMILY SSF51735 1 303 8.39E-90 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS17365 fecc23b2a96b8903f71bb0e8838da385 308 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 232 1.1E-55 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CIG75_RS17365 fecc23b2a96b8903f71bb0e8838da385 308 Gene3D G3DSA:3.40.50.720 1 162 1.9E-31 T 28-03-2018 CIG75_RS17365 fecc23b2a96b8903f71bb0e8838da385 308 Gene3D G3DSA:3.90.25.10 163 308 8.1E-40 T 28-03-2018 CIG75_RS04190 c964e4cc3ac5e1db5cacd55dc17d46e2 449 SMART SM00028 208 241 60.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS04190 c964e4cc3ac5e1db5cacd55dc17d46e2 449 SMART SM00028 370 403 350.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS04190 c964e4cc3ac5e1db5cacd55dc17d46e2 449 SMART SM00028 167 200 64.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS04190 c964e4cc3ac5e1db5cacd55dc17d46e2 449 SMART SM00028 288 321 0.66 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS04190 c964e4cc3ac5e1db5cacd55dc17d46e2 449 SMART SM00028 328 361 9.2 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS04190 c964e4cc3ac5e1db5cacd55dc17d46e2 449 SMART SM00028 248 281 23.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS04190 c964e4cc3ac5e1db5cacd55dc17d46e2 449 SUPERFAMILY SSF47413 21 78 9.29E-13 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CIG75_RS04190 c964e4cc3ac5e1db5cacd55dc17d46e2 449 Gene3D G3DSA:1.25.40.10 220 265 2.6E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS04190 c964e4cc3ac5e1db5cacd55dc17d46e2 449 Gene3D G3DSA:1.25.40.10 266 304 1.5E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS04190 c964e4cc3ac5e1db5cacd55dc17d46e2 449 SUPERFAMILY SSF48452 254 425 1.27E-18 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS04190 c964e4cc3ac5e1db5cacd55dc17d46e2 449 Gene3D G3DSA:1.10.150.200 172 219 5.6E-4 T 28-03-2018 CIG75_RS04190 c964e4cc3ac5e1db5cacd55dc17d46e2 449 SMART SM00530 24 78 2.6E-10 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS04190 c964e4cc3ac5e1db5cacd55dc17d46e2 449 Gene3D G3DSA:1.25.40.10 305 350 9.7E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS04190 c964e4cc3ac5e1db5cacd55dc17d46e2 449 Gene3D G3DSA:1.10.3100.10 14 171 6.5E-18 T 28-03-2018 IPR027910 YdiL-like domain CIG75_RS04190 c964e4cc3ac5e1db5cacd55dc17d46e2 449 Pfam PF01381 Helix-turn-helix 25 76 1.1E-9 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS04190 c964e4cc3ac5e1db5cacd55dc17d46e2 449 SUPERFAMILY SSF48452 168 281 9.21E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS04190 c964e4cc3ac5e1db5cacd55dc17d46e2 449 Pfam PF13176 Tetratricopeptide repeat 330 360 0.012 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS04190 c964e4cc3ac5e1db5cacd55dc17d46e2 449 Gene3D G3DSA:1.25.40.10 351 448 3.2E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS04190 c964e4cc3ac5e1db5cacd55dc17d46e2 449 Pfam PF13424 Tetratricopeptide repeat 258 319 2.1E-9 T 28-03-2018 CIG75_RS06695 098b7cd4c843d14af654598697a3c62d 388 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 11 382 3.6E-62 T 28-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 CIG75_RS06695 098b7cd4c843d14af654598697a3c62d 388 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 223 378 6.7E-19 T 28-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 CIG75_RS20345 c13099132d2d5a16cde62989bbab1ca5 286 ProDom PD127708 YABG PROTEASE SPORULATION-SPECIFIC PEPTIDASE U57 BH0058 ORTHOLOG SPORE FAMILY B.SUBTILIS 8 276 1.0E-72 T 28-03-2018 IPR008764 Peptidase U57, YabG CIG75_RS20345 c13099132d2d5a16cde62989bbab1ca5 286 PIRSF PIRSF011575 1 286 2.0E-109 T 28-03-2018 IPR008764 Peptidase U57, YabG CIG75_RS20345 c13099132d2d5a16cde62989bbab1ca5 286 TIGRFAM TIGR02855 spore_yabG: sporulation peptidase YabG 3 282 1.8E-109 T 28-03-2018 IPR008764 Peptidase U57, YabG CIG75_RS20345 c13099132d2d5a16cde62989bbab1ca5 286 Pfam PF05582 YabG peptidase U57 3 282 3.2E-113 T 28-03-2018 IPR008764 Peptidase U57, YabG CIG75_RS19595 4b407ee51e372d1a28560a8cd0fd0464 208 SMART SM01390 3 97 3.6E-57 T 28-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 CIG75_RS19595 4b407ee51e372d1a28560a8cd0fd0464 208 Gene3D G3DSA:1.10.1050.10 147 208 3.0E-11 T 28-03-2018 CIG75_RS19595 4b407ee51e372d1a28560a8cd0fd0464 208 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 208 4.1E-74 T 28-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 CIG75_RS19595 4b407ee51e372d1a28560a8cd0fd0464 208 SUPERFAMILY SSF55174 3 208 2.62E-70 T 28-03-2018 CIG75_RS19595 4b407ee51e372d1a28560a8cd0fd0464 208 Gene3D G3DSA:3.10.290.10 104 146 2.5E-17 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CIG75_RS19595 4b407ee51e372d1a28560a8cd0fd0464 208 Pfam PF01479 S4 domain 99 145 1.6E-20 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CIG75_RS19595 4b407ee51e372d1a28560a8cd0fd0464 208 SMART SM00363 98 162 1.7E-20 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CIG75_RS19595 4b407ee51e372d1a28560a8cd0fd0464 208 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 97 1.2E-33 T 28-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 CIG75_RS19595 4b407ee51e372d1a28560a8cd0fd0464 208 ProSitePatterns PS00632 Ribosomal protein S4 signature. 96 120 - T 28-03-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CIG75_RS19595 4b407ee51e372d1a28560a8cd0fd0464 208 Gene3D G3DSA:1.10.1050.10 1 103 1.1E-43 T 28-03-2018 CIG75_RS19595 4b407ee51e372d1a28560a8cd0fd0464 208 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 208 36.544 T 28-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 CIG75_RS04910 1fc0f43efd08fe8f430e7e1c9aafcf95 200 SUPERFAMILY SSF88659 112 181 4.49E-18 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS04910 1fc0f43efd08fe8f430e7e1c9aafcf95 200 Gene3D G3DSA:1.10.10.10 95 183 1.2E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS04910 1fc0f43efd08fe8f430e7e1c9aafcf95 200 Pfam PF04542 Sigma-70 region 2 24 89 1.3E-21 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS04910 1fc0f43efd08fe8f430e7e1c9aafcf95 200 Gene3D G3DSA:1.10.1740.10 1 94 3.1E-29 T 28-03-2018 CIG75_RS04910 1fc0f43efd08fe8f430e7e1c9aafcf95 200 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 22 180 3.4E-39 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS04910 1fc0f43efd08fe8f430e7e1c9aafcf95 200 SUPERFAMILY SSF88946 2 103 1.73E-31 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS04910 1fc0f43efd08fe8f430e7e1c9aafcf95 200 Pfam PF08281 Sigma-70, region 4 124 175 2.0E-18 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS06940 e816339ee70bc4556ebc7406df09af76 586 SUPERFAMILY SSF54106 224 268 9.68E-7 T 28-03-2018 IPR018392 LysM domain CIG75_RS06940 e816339ee70bc4556ebc7406df09af76 586 SUPERFAMILY SSF54106 167 212 9.81E-7 T 28-03-2018 IPR018392 LysM domain CIG75_RS06940 e816339ee70bc4556ebc7406df09af76 586 Gene3D G3DSA:3.10.350.10 218 281 1.1E-8 T 28-03-2018 CIG75_RS06940 e816339ee70bc4556ebc7406df09af76 586 SMART SM00257 225 268 8.7E-6 T 28-03-2018 IPR018392 LysM domain CIG75_RS06940 e816339ee70bc4556ebc7406df09af76 586 SMART SM00257 168 212 0.25 T 28-03-2018 IPR018392 LysM domain CIG75_RS06940 e816339ee70bc4556ebc7406df09af76 586 Pfam PF01476 LysM domain 169 212 1.7E-4 T 28-03-2018 IPR018392 LysM domain CIG75_RS06940 e816339ee70bc4556ebc7406df09af76 586 Pfam PF01476 LysM domain 226 268 5.2E-5 T 28-03-2018 IPR018392 LysM domain CIG75_RS06940 e816339ee70bc4556ebc7406df09af76 586 Gene3D G3DSA:3.10.350.10 167 214 5.9E-7 T 28-03-2018 CIG75_RS06940 e816339ee70bc4556ebc7406df09af76 586 SUPERFAMILY SSF51445 536 573 6.77E-10 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CIG75_RS06940 e816339ee70bc4556ebc7406df09af76 586 SUPERFAMILY SSF51445 346 482 6.77E-10 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CIG75_RS06940 e816339ee70bc4556ebc7406df09af76 586 Gene3D G3DSA:3.20.20.80 320 581 1.5E-9 T 28-03-2018 CIG75_RS15195 cb837193622a88e74ba1c5955e5a0c87 576 SUPERFAMILY SSF53323 2 217 1.7E-36 T 28-03-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 CIG75_RS15195 cb837193622a88e74ba1c5955e5a0c87 576 SUPERFAMILY SSF52922 469 575 9.55E-21 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CIG75_RS15195 cb837193622a88e74ba1c5955e5a0c87 576 Gene3D G3DSA:3.40.50.970 194 448 1.1E-54 T 28-03-2018 CIG75_RS15195 cb837193622a88e74ba1c5955e5a0c87 576 Gene3D G3DSA:3.40.920.10 2 182 6.7E-39 T 28-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CIG75_RS15195 cb837193622a88e74ba1c5955e5a0c87 576 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 209 451 5.9E-58 T 28-03-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 CIG75_RS15195 cb837193622a88e74ba1c5955e5a0c87 576 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 475 540 5.0E-10 T 28-03-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II CIG75_RS15195 cb837193622a88e74ba1c5955e5a0c87 576 Gene3D G3DSA:3.40.50.920 464 576 1.0E-12 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CIG75_RS15195 cb837193622a88e74ba1c5955e5a0c87 576 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 14 174 3.3E-36 T 28-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CIG75_RS15195 cb837193622a88e74ba1c5955e5a0c87 576 SUPERFAMILY SSF52518 195 457 4.32E-68 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CIG75_RS15195 cb837193622a88e74ba1c5955e5a0c87 576 TIGRFAM TIGR03710 OAFO_sf: 2-oxoacid:acceptor oxidoreductase, alpha subunit 5 570 9.6E-195 T 28-03-2018 IPR022367 2-oxoacid:acceptor oxidoreductase, alpha subunit KEGG: 00020+1.2.7.3|KEGG: 00720+1.2.7.3|MetaCyc: PWY-5392|MetaCyc: PWY-6969 CIG75_RS09645 f386de15013051e25020adc806173fde 386 SUPERFAMILY SSF102114 21 357 3.27E-43 T 28-03-2018 CIG75_RS09645 f386de15013051e25020adc806173fde 386 PIRSF PIRSF004762 2 375 3.1E-122 T 28-03-2018 CIG75_RS09645 f386de15013051e25020adc806173fde 386 Pfam PF04055 Radical SAM superfamily 64 233 1.5E-15 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CIG75_RS09645 f386de15013051e25020adc806173fde 386 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 57 363 1.7E-114 T 28-03-2018 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 CIG75_RS09645 f386de15013051e25020adc806173fde 386 Hamap MF_00993 Aminodeoxyfutalosine synthase [mqnE]. 11 367 51.568 T 28-03-2018 IPR022432 Aminodeoxyfutalosine synthase GO:0009234 KEGG: 00130+2.5.1.120|MetaCyc: PWY-7371|MetaCyc: PWY-7374 CIG75_RS09645 f386de15013051e25020adc806173fde 386 Gene3D G3DSA:3.20.20.70 4 366 2.2E-48 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CIG75_RS09645 f386de15013051e25020adc806173fde 386 TIGRFAM TIGR03700 mena_SCO4494: putative menaquinone biosynthesis radical SAM enzyme, SCO4494 family 13 364 2.0E-148 T 28-03-2018 IPR022432 Aminodeoxyfutalosine synthase GO:0009234 KEGG: 00130+2.5.1.120|MetaCyc: PWY-7371|MetaCyc: PWY-7374 CIG75_RS11040 315d4e17e6ff30f928e2b26b9341f9ca 235 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 110 216 7.9E-13 T 28-03-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CIG75_RS11040 315d4e17e6ff30f928e2b26b9341f9ca 235 SUPERFAMILY SSF56214 110 232 4.71E-26 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CIG75_RS11040 315d4e17e6ff30f928e2b26b9341f9ca 235 Gene3D G3DSA:3.90.470.20 4 118 6.8E-17 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CIG75_RS11040 315d4e17e6ff30f928e2b26b9341f9ca 235 Gene3D G3DSA:3.90.470.20 119 216 3.6E-16 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CIG75_RS11040 315d4e17e6ff30f928e2b26b9341f9ca 235 SUPERFAMILY SSF56214 5 101 2.51E-18 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CIG75_RS11040 315d4e17e6ff30f928e2b26b9341f9ca 235 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 110 215 5.6E-17 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CIG75_RS00215 2a82181d296aa206facd271d214027b2 378 PIRSF PIRSF000804 1 378 1.2E-119 T 28-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CIG75_RS00215 2a82181d296aa206facd271d214027b2 378 Pfam PF02767 DNA polymerase III beta subunit, central domain 137 252 3.9E-34 T 28-03-2018 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CIG75_RS00215 2a82181d296aa206facd271d214027b2 378 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 127 3.0E-36 T 28-03-2018 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CIG75_RS00215 2a82181d296aa206facd271d214027b2 378 SUPERFAMILY SSF55979 255 377 5.71E-31 T 28-03-2018 CIG75_RS00215 2a82181d296aa206facd271d214027b2 378 SUPERFAMILY SSF55979 134 252 1.63E-27 T 28-03-2018 CIG75_RS00215 2a82181d296aa206facd271d214027b2 378 SMART SM00480 17 373 1.1E-143 T 28-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CIG75_RS00215 2a82181d296aa206facd271d214027b2 378 SUPERFAMILY SSF55979 1 127 3.62E-26 T 28-03-2018 CIG75_RS00215 2a82181d296aa206facd271d214027b2 378 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 376 8.9E-111 T 28-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CIG75_RS00215 2a82181d296aa206facd271d214027b2 378 Gene3D G3DSA:3.10.150.10 130 257 4.5E-34 T 28-03-2018 CIG75_RS00215 2a82181d296aa206facd271d214027b2 378 Gene3D G3DSA:3.10.150.10 1 129 4.9E-31 T 28-03-2018 CIG75_RS00215 2a82181d296aa206facd271d214027b2 378 Gene3D G3DSA:3.10.150.10 258 377 5.9E-26 T 28-03-2018 CIG75_RS00215 2a82181d296aa206facd271d214027b2 378 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 255 376 3.2E-31 T 28-03-2018 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CIG75_RS09575 b8a7065e5316d868f81912c1268a6cf8 379 Pfam PF05816 Toxic anion resistance protein (TelA) 58 369 9.5E-75 T 28-03-2018 IPR008863 Toxic anion resistance CIG75_RS09575 b8a7065e5316d868f81912c1268a6cf8 379 PIRSF PIRSF026508 3 377 3.3E-71 T 28-03-2018 IPR008863 Toxic anion resistance CIG75_RS01855 507928ae524537163df543215c11517e 228 Gene3D G3DSA:3.40.50.2300 1 228 5.5E-41 T 28-03-2018 CIG75_RS01855 507928ae524537163df543215c11517e 228 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 4 117 2.3E-28 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CIG75_RS01855 507928ae524537163df543215c11517e 228 SMART SM00226 1 142 1.1E-20 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CIG75_RS01855 507928ae524537163df543215c11517e 228 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 3 20 5.2E-8 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CIG75_RS01855 507928ae524537163df543215c11517e 228 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 45 61 5.2E-8 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CIG75_RS01855 507928ae524537163df543215c11517e 228 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 79 94 5.2E-8 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CIG75_RS01855 507928ae524537163df543215c11517e 228 SUPERFAMILY SSF52788 1 118 3.27E-31 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CIG75_RS00240 ae56fe6fc39bd63b862a5591bf070858 248 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 52 230 1.6E-58 T 28-03-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal CIG75_RS00240 ae56fe6fc39bd63b862a5591bf070858 248 Pfam PF02096 60Kd inner membrane protein 52 230 1.8E-56 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CIG75_RS14250 f1668beaec17f98812a130dfaa796bcf 125 Pfam PF04237 YjbR 25 110 9.2E-11 T 28-03-2018 IPR007351 Uncharacterised protein YjbR CIG75_RS14250 f1668beaec17f98812a130dfaa796bcf 125 SUPERFAMILY SSF142906 17 122 1.07E-12 T 28-03-2018 CIG75_RS14250 f1668beaec17f98812a130dfaa796bcf 125 Gene3D G3DSA:3.30.1460.30 12 114 2.5E-7 T 28-03-2018 CIG75_RS07075 ce8ea015e0eb4e2b98fe5e3f206cab5f 253 Pfam PF13649 Methyltransferase domain 46 141 4.0E-20 T 28-03-2018 CIG75_RS07075 ce8ea015e0eb4e2b98fe5e3f206cab5f 253 Gene3D G3DSA:3.40.50.150 2 145 1.4E-23 T 28-03-2018 CIG75_RS07075 ce8ea015e0eb4e2b98fe5e3f206cab5f 253 SUPERFAMILY SSF53335 9 253 6.37E-51 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CIG75_RS07075 ce8ea015e0eb4e2b98fe5e3f206cab5f 253 Gene3D G3DSA:2.20.25.110 149 213 8.9E-20 T 28-03-2018 CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1019 1034 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 Gene3D G3DSA:3.40.50.980 474 619 2.1E-33 T 28-03-2018 CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 Pfam PF00668 Condensation domain 1082 1526 1.3E-121 T 28-03-2018 IPR001242 Condensation domain CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 Pfam PF00668 Condensation domain 18 462 9.5E-123 T 28-03-2018 IPR001242 Condensation domain CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 Pfam PF00668 Condensation domain 4263 4714 8.8E-124 T 28-03-2018 IPR001242 Condensation domain CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 Pfam PF00668 Condensation domain 3212 3659 1.1E-130 T 28-03-2018 IPR001242 Condensation domain CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 Pfam PF00668 Condensation domain 2147 2592 1.5E-125 T 28-03-2018 IPR001242 Condensation domain CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 Gene3D G3DSA:3.40.50.980 4727 4880 2.1E-42 T 28-03-2018 CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 Pfam PF00501 AMP-binding enzyme 4734 5135 7.4E-91 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 Pfam PF00501 AMP-binding enzyme 482 884 4.7E-90 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 Pfam PF00501 AMP-binding enzyme 1547 1953 1.4E-97 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 Pfam PF00501 AMP-binding enzyme 3679 4070 6.8E-105 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 Pfam PF00501 AMP-binding enzyme 2612 3014 2.1E-91 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 SMART SM00824 Thioesterase 5338 5585 6.0E-7 T 28-03-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2754 2765 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 ProSitePatterns PS00455 Putative AMP-binding domain signature. 624 635 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 Gene3D G3DSA:1.10.1200.10 999 1068 1.3E-21 T 28-03-2018 CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 ProSitePatterns PS00455 Putative AMP-binding domain signature. 4876 4887 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 SUPERFAMILY SSF52777 21 197 5.48E-53 T 28-03-2018 CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 SUPERFAMILY SSF47336 3118 3226 1.24E-20 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 SUPERFAMILY SSF47336 4171 4243 3.53E-21 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 4755 5158 5.7E-130 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1568 1977 4.1E-127 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2633 3038 5.7E-127 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 503 908 6.8E-121 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 3700 4094 4.5E-134 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1689 1700 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 SUPERFAMILY SSF52777 4266 4449 6.45E-45 T 28-03-2018 CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 SUPERFAMILY SSF52777 205 469 1.78E-68 T 28-03-2018 CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 Gene3D G3DSA:3.30.559.10 4254 4457 3.6E-40 T 28-03-2018 CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 Gene3D G3DSA:3.30.559.10 2130 2330 4.1E-46 T 28-03-2018 CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 Pfam PF00550 Phosphopantetheine attachment site 3127 3189 4.3E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 Pfam PF00550 Phosphopantetheine attachment site 2063 2121 4.3E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 Pfam PF00550 Phosphopantetheine attachment site 4179 4243 1.5E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 Pfam PF00550 Phosphopantetheine attachment site 5244 5307 3.2E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 Pfam PF00550 Phosphopantetheine attachment site 996 1060 1.0E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 SUPERFAMILY SSF56801 4691 5254 3.14E-150 T 28-03-2018 CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 Gene3D G3DSA:2.30.38.10 798 874 6.6E-24 T 28-03-2018 CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 Gene3D G3DSA:2.30.38.10 2922 3004 6.1E-23 T 28-03-2018 CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 Gene3D G3DSA:2.30.38.10 1863 1943 6.4E-25 T 28-03-2018 CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 SUPERFAMILY SSF52777 4456 4720 1.45E-67 T 28-03-2018 CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3149 3164 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 SUPERFAMILY SSF52777 2335 2575 2.08E-67 T 28-03-2018 CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 SMART SM00823 Phosphopantetheine attachment site 2059 2131 0.0027 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 SMART SM00823 Phosphopantetheine attachment site 995 1064 0.023 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 SMART SM00823 Phosphopantetheine attachment site 4178 4247 5.8E-5 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 SMART SM00823 Phosphopantetheine attachment site 5242 5311 4.2E-4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 SMART SM00823 Phosphopantetheine attachment site 3125 3194 0.0022 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 Gene3D G3DSA:3.40.50.980 620 797 2.6E-41 T 28-03-2018 CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 SUPERFAMILY SSF47336 2051 2160 1.27E-18 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 SUPERFAMILY SSF56801 3637 4190 2.88E-162 T 28-03-2018 CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4202 4217 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 SUPERFAMILY SSF53474 5313 5585 1.66E-55 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 SUPERFAMILY SSF52777 2150 2327 3.22E-51 T 28-03-2018 CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 SUPERFAMILY SSF52777 1086 1263 2.45E-52 T 28-03-2018 CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 Pfam PF13193 AMP-binding enzyme C-terminal domain 5143 5216 9.9E-7 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 Pfam PF13193 AMP-binding enzyme C-terminal domain 892 967 7.3E-10 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 Pfam PF13193 AMP-binding enzyme C-terminal domain 4079 4151 1.2E-10 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 Pfam PF13193 AMP-binding enzyme C-terminal domain 3022 3097 1.2E-14 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 Pfam PF13193 AMP-binding enzyme C-terminal domain 1961 2034 1.9E-11 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 Gene3D G3DSA:1.10.1200.10 4184 4253 7.4E-24 T 28-03-2018 CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 SUPERFAMILY SSF47336 5234 5308 1.31E-19 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 SUPERFAMILY SSF47336 987 1096 1.7E-19 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 Gene3D G3DSA:3.40.50.980 4881 5033 1.1E-28 T 28-03-2018 CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 Gene3D G3DSA:3.40.50.980 2760 2918 1.2E-29 T 28-03-2018 CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 Gene3D G3DSA:3.40.50.980 3826 3972 4.2E-38 T 28-03-2018 CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 Gene3D G3DSA:3.40.50.980 1695 1855 1.4E-27 T 28-03-2018 CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 Gene3D G3DSA:3.30.559.10 3195 3416 4.9E-51 T 28-03-2018 CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 Gene3D G3DSA:3.30.559.10 1069 1288 6.0E-51 T 28-03-2018 CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 Gene3D G3DSA:3.30.559.10 4 221 5.0E-50 T 28-03-2018 CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 SUPERFAMILY SSF52777 3216 3393 6.23E-50 T 28-03-2018 CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 SUPERFAMILY SSF56801 2569 3137 3.4E-158 T 28-03-2018 CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 Gene3D G3DSA:2.30.38.10 5034 5127 2.5E-22 T 28-03-2018 CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 Gene3D G3DSA:2.30.38.10 3973 4062 1.1E-23 T 28-03-2018 CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 Gene3D G3DSA:3.30.300.30 3009 3132 5.9E-42 T 28-03-2018 CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 Gene3D G3DSA:3.30.300.30 879 998 7.4E-39 T 28-03-2018 CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 Gene3D G3DSA:3.30.300.30 1948 2064 7.4E-36 T 28-03-2018 CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 Gene3D G3DSA:3.30.300.30 5130 5247 1.7E-36 T 28-03-2018 CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 Gene3D G3DSA:3.30.300.30 4065 4183 2.3E-35 T 28-03-2018 CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 SUPERFAMILY SSF52777 1271 1532 2.89E-65 T 28-03-2018 CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 Pfam PF00975 Thioesterase domain 5333 5575 1.1E-28 T 28-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2083 2098 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 Gene3D G3DSA:3.40.50.980 3670 3825 6.6E-47 T 28-03-2018 CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 Gene3D G3DSA:3.40.50.980 1538 1694 5.3E-49 T 28-03-2018 CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 Gene3D G3DSA:3.40.50.980 2603 2759 2.0E-47 T 28-03-2018 CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 ProSitePatterns PS00012 Phosphopantetheine attachment site. 5266 5281 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 Gene3D G3DSA:3.40.50.1820 5324 5586 1.4E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 Gene3D G3DSA:1.10.1200.10 5248 5314 3.4E-22 T 28-03-2018 CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 Gene3D G3DSA:1.10.1200.10 2065 2129 6.7E-21 T 28-03-2018 CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 Gene3D G3DSA:1.10.1200.10 3133 3194 2.4E-22 T 28-03-2018 CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 SUPERFAMILY SSF56801 1505 2071 2.49E-158 T 28-03-2018 CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 SUPERFAMILY SSF56801 440 1008 2.88E-158 T 28-03-2018 CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 ProSitePatterns PS00455 Putative AMP-binding domain signature. 3820 3831 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS09800 94fd04b69710e42f33d6d17696ab6b26 5590 SUPERFAMILY SSF52777 3399 3666 4.67E-68 T 28-03-2018 CIG75_RS04790 50b966acf72d586b259d4760f125a48a 365 Gene3D G3DSA:3.30.565.10 202 362 1.0E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS04790 50b966acf72d586b259d4760f125a48a 365 SUPERFAMILY SSF55874 196 360 8.91E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS04790 50b966acf72d586b259d4760f125a48a 365 SMART SM00388 140 207 5.7E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CIG75_RS04790 50b966acf72d586b259d4760f125a48a 365 PRINTS PR00344 Bacterial sensor protein C-terminal signature 289 303 7.2E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS04790 50b966acf72d586b259d4760f125a48a 365 PRINTS PR00344 Bacterial sensor protein C-terminal signature 307 317 7.2E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS04790 50b966acf72d586b259d4760f125a48a 365 PRINTS PR00344 Bacterial sensor protein C-terminal signature 347 360 7.2E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS04790 50b966acf72d586b259d4760f125a48a 365 PRINTS PR00344 Bacterial sensor protein C-terminal signature 324 342 7.2E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS04790 50b966acf72d586b259d4760f125a48a 365 SMART SM00387 252 363 9.5E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS04790 50b966acf72d586b259d4760f125a48a 365 SMART SM00304 80 132 1.8E-5 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CIG75_RS04790 50b966acf72d586b259d4760f125a48a 365 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 252 361 9.6E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS04790 50b966acf72d586b259d4760f125a48a 365 SUPERFAMILY SSF158472 93 130 6.54E-5 T 28-03-2018 CIG75_RS04790 50b966acf72d586b259d4760f125a48a 365 Gene3D G3DSA:1.10.287.130 125 201 9.5E-14 T 28-03-2018 CIG75_RS04790 50b966acf72d586b259d4760f125a48a 365 Pfam PF00512 His Kinase A (phospho-acceptor) domain 140 205 1.2E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CIG75_RS04790 50b966acf72d586b259d4760f125a48a 365 SUPERFAMILY SSF47384 126 208 7.46E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CIG75_RS17320 211f106e4fd426b5811ef2a4e376c334 463 Gene3D G3DSA:3.40.50.20 22 130 3.4E-4 T 28-03-2018 CIG75_RS17320 211f106e4fd426b5811ef2a4e376c334 463 SUPERFAMILY SSF56059 111 198 1.64E-37 T 28-03-2018 CIG75_RS17320 211f106e4fd426b5811ef2a4e376c334 463 SUPERFAMILY SSF56059 225 364 1.64E-37 T 28-03-2018 CIG75_RS17320 211f106e4fd426b5811ef2a4e376c334 463 Pfam PF13535 ATP-grasp domain 162 334 1.9E-17 T 28-03-2018 CIG75_RS17320 211f106e4fd426b5811ef2a4e376c334 463 Gene3D G3DSA:3.30.1490.20 131 226 1.7E-16 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CIG75_RS17320 211f106e4fd426b5811ef2a4e376c334 463 Gene3D G3DSA:3.30.470.20 227 426 3.4E-22 T 28-03-2018 CIG75_RS05600 8663406b53a59c94ffeb05d9fd389657 343 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS05600 8663406b53a59c94ffeb05d9fd389657 343 SMART SM00382 33 243 1.4E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS05600 8663406b53a59c94ffeb05d9fd389657 343 SUPERFAMILY SSF52540 32 319 2.15E-70 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS05600 8663406b53a59c94ffeb05d9fd389657 343 Pfam PF00005 ABC transporter 25 185 5.0E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS05600 8663406b53a59c94ffeb05d9fd389657 343 Gene3D G3DSA:3.40.50.300 1 336 5.8E-82 T 28-03-2018 CIG75_RS05600 8663406b53a59c94ffeb05d9fd389657 343 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 235 322 3.1E-28 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CIG75_RS05600 8663406b53a59c94ffeb05d9fd389657 343 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 237 302 2.1E-21 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CIG75_RS03525 61e01e071ebef6340a2cd12dc6e702dd 424 Pfam PF07730 Histidine kinase 219 284 8.4E-17 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CIG75_RS03525 61e01e071ebef6340a2cd12dc6e702dd 424 Gene3D G3DSA:3.30.565.10 193 413 6.3E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS03525 61e01e071ebef6340a2cd12dc6e702dd 424 SUPERFAMILY SSF55874 289 412 1.14E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS07895 58bdfa685f1b828a35e4d9521b4d3a0b 213 Gene3D G3DSA:3.40.50.720 4 121 8.1E-21 T 28-03-2018 CIG75_RS07895 58bdfa685f1b828a35e4d9521b4d3a0b 213 Pfam PF13241 Putative NAD(P)-binding 8 116 2.2E-26 T 28-03-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CIG75_RS07895 58bdfa685f1b828a35e4d9521b4d3a0b 213 Pfam PF14824 Sirohaem biosynthesis protein central 120 146 5.7E-8 T 28-03-2018 IPR028281 Siroheme synthase, central domain KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CIG75_RS07895 58bdfa685f1b828a35e4d9521b4d3a0b 213 SUPERFAMILY SSF75615 115 210 2.35E-21 T 28-03-2018 CIG75_RS07895 58bdfa685f1b828a35e4d9521b4d3a0b 213 Gene3D G3DSA:3.30.160.110 122 148 2.2E-13 T 28-03-2018 CIG75_RS07895 58bdfa685f1b828a35e4d9521b4d3a0b 213 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 8 207 1.2E-45 T 28-03-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CIG75_RS07895 58bdfa685f1b828a35e4d9521b4d3a0b 213 SUPERFAMILY SSF51735 4 113 1.24E-19 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS01980 217b865ed219fd44eb5de4e288e6172d 145 Gene3D G3DSA:3.30.70.20 53 90 1.0E-14 T 28-03-2018 CIG75_RS01980 217b865ed219fd44eb5de4e288e6172d 145 TIGRFAM TIGR01971 NuoI: NADH-quinone oxidoreductase, chain I 7 117 2.0E-34 T 28-03-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CIG75_RS01980 217b865ed219fd44eb5de4e288e6172d 145 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 85 96 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CIG75_RS01980 217b865ed219fd44eb5de4e288e6172d 145 Pfam PF12838 4Fe-4S dicluster domain 45 99 5.6E-10 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CIG75_RS01980 217b865ed219fd44eb5de4e288e6172d 145 Gene3D G3DSA:3.30.70.20 91 138 5.5E-6 T 28-03-2018 CIG75_RS01980 217b865ed219fd44eb5de4e288e6172d 145 Gene3D G3DSA:3.30.70.20 19 52 3.6E-5 T 28-03-2018 CIG75_RS01980 217b865ed219fd44eb5de4e288e6172d 145 SUPERFAMILY SSF54862 24 128 2.05E-24 T 28-03-2018 CIG75_RS00655 87668080819ed315a294cd5e63fc65c0 167 SUPERFAMILY SSF46785 3 146 1.4E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS00655 87668080819ed315a294cd5e63fc65c0 167 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 28-03-2018 IPR030489 Transcription regulator Rrf2-type, conserved site CIG75_RS00655 87668080819ed315a294cd5e63fc65c0 167 Pfam PF02082 Transcriptional regulator 1 83 1.0E-26 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type CIG75_RS00655 87668080819ed315a294cd5e63fc65c0 167 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 140 8.4E-30 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type CIG75_RS00655 87668080819ed315a294cd5e63fc65c0 167 Gene3D G3DSA:1.10.10.10 1 157 2.2E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS10450 039a907c61c2c8d5055302966beab004 421 Gene3D G3DSA:3.30.70.20 382 410 3.2E-4 T 28-03-2018 CIG75_RS10450 039a907c61c2c8d5055302966beab004 421 SUPERFAMILY SSF54862 335 404 1.4E-12 T 28-03-2018 CIG75_RS10450 039a907c61c2c8d5055302966beab004 421 SUPERFAMILY SSF51395 1 318 2.1E-71 T 28-03-2018 CIG75_RS10450 039a907c61c2c8d5055302966beab004 421 Gene3D G3DSA:3.30.70.20 330 381 4.5E-9 T 28-03-2018 CIG75_RS10450 039a907c61c2c8d5055302966beab004 421 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 380 391 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CIG75_RS10450 039a907c61c2c8d5055302966beab004 421 Gene3D G3DSA:3.20.20.70 4 308 4.2E-47 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CIG75_RS10450 039a907c61c2c8d5055302966beab004 421 Pfam PF14697 4Fe-4S dicluster domain 335 398 1.3E-22 T 28-03-2018 CIG75_RS10450 039a907c61c2c8d5055302966beab004 421 Pfam PF01180 Dihydroorotate dehydrogenase 112 302 3.6E-30 T 28-03-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 CIG75_RS10450 039a907c61c2c8d5055302966beab004 421 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 4 317 1.1E-56 T 28-03-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 CIG75_RS00770 0ce2a37b5661690b928b7cf5a344347f 380 Pfam PF14286 DHHW protein 111 339 4.6E-29 T 28-03-2018 IPR025945 DHHW protein CIG75_RS06020 261b45adfc9f1d90200bb45ca32db96b 808 Pfam PF03147 Ferredoxin-fold anticodon binding domain 714 807 6.1E-30 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CIG75_RS06020 261b45adfc9f1d90200bb45ca32db96b 808 SUPERFAMILY SSF55681 475 700 6.21E-52 T 28-03-2018 CIG75_RS06020 261b45adfc9f1d90200bb45ca32db96b 808 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 807 8.2E-257 T 28-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 CIG75_RS06020 261b45adfc9f1d90200bb45ca32db96b 808 Gene3D G3DSA:3.30.70.380 711 807 1.1E-25 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CIG75_RS06020 261b45adfc9f1d90200bb45ca32db96b 808 SUPERFAMILY SSF56037 215 399 5.49E-64 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CIG75_RS06020 261b45adfc9f1d90200bb45ca32db96b 808 Pfam PF01409 tRNA synthetases class II core domain (F) 482 611 1.8E-4 T 28-03-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 CIG75_RS06020 261b45adfc9f1d90200bb45ca32db96b 808 Gene3D G3DSA:3.50.40.10 203 403 1.2E-66 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CIG75_RS06020 261b45adfc9f1d90200bb45ca32db96b 808 Pfam PF03483 B3/4 domain 219 392 4.0E-62 T 28-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CIG75_RS06020 261b45adfc9f1d90200bb45ca32db96b 808 SMART SM00896 714 807 1.6E-46 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CIG75_RS06020 261b45adfc9f1d90200bb45ca32db96b 808 Pfam PF01588 Putative tRNA binding domain 46 152 2.3E-24 T 28-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 CIG75_RS06020 261b45adfc9f1d90200bb45ca32db96b 808 SUPERFAMILY SSF50249 39 198 2.94E-45 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CIG75_RS06020 261b45adfc9f1d90200bb45ca32db96b 808 SUPERFAMILY SSF46955 409 483 6.96E-19 T 28-03-2018 IPR009061 Putative DNA-binding domain CIG75_RS06020 261b45adfc9f1d90200bb45ca32db96b 808 Gene3D G3DSA:2.40.50.140 56 161 1.3E-42 T 28-03-2018 CIG75_RS06020 261b45adfc9f1d90200bb45ca32db96b 808 Pfam PF03484 tRNA synthetase B5 domain 413 479 2.5E-21 T 28-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CIG75_RS06020 261b45adfc9f1d90200bb45ca32db96b 808 SUPERFAMILY SSF54991 711 807 5.36E-31 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CIG75_RS06020 261b45adfc9f1d90200bb45ca32db96b 808 Gene3D G3DSA:3.30.56.10 1 55 4.4E-11 T 28-03-2018 CIG75_RS06020 261b45adfc9f1d90200bb45ca32db96b 808 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 801 45.095 T 28-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 CIG75_RS06020 261b45adfc9f1d90200bb45ca32db96b 808 SMART SM00873 218 392 2.3E-83 T 28-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CIG75_RS06020 261b45adfc9f1d90200bb45ca32db96b 808 Gene3D G3DSA:3.30.930.10 493 703 1.7E-42 T 28-03-2018 CIG75_RS06020 261b45adfc9f1d90200bb45ca32db96b 808 SMART SM00874 409 479 1.2E-30 T 28-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CIG75_RS06020 261b45adfc9f1d90200bb45ca32db96b 808 Gene3D G3DSA:3.30.56.10 408 483 2.2E-25 T 28-03-2018 CIG75_RS10975 20dd5eca7430be16c726a4004fc9f271 300 SUPERFAMILY SSF55469 96 176 2.43E-17 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CIG75_RS10975 20dd5eca7430be16c726a4004fc9f271 300 SUPERFAMILY SSF55469 210 296 2.43E-17 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CIG75_RS10975 20dd5eca7430be16c726a4004fc9f271 300 Gene3D G3DSA:3.40.109.10 34 297 3.2E-34 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CIG75_RS10975 20dd5eca7430be16c726a4004fc9f271 300 Pfam PF00881 Nitroreductase family 101 295 1.2E-16 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CIG75_RS10975 20dd5eca7430be16c726a4004fc9f271 300 TIGRFAM TIGR03605 antibiot_sagB: SagB-type dehydrogenase domain 117 296 7.2E-37 T 28-03-2018 IPR020051 SagB-type dehydrogenase domain CIG75_RS16925 b8b692a5f2971f2173d5d1d24383314b 404 Gene3D G3DSA:3.30.950.10 110 207 1.4E-28 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CIG75_RS16925 b8b692a5f2971f2173d5d1d24383314b 404 SUPERFAMILY SSF53335 229 359 1.13E-26 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CIG75_RS16925 b8b692a5f2971f2173d5d1d24383314b 404 TIGRFAM TIGR02469 CbiT: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit 229 349 4.8E-34 T 28-03-2018 IPR014008 Cobalamin biosynthesis, precorrin-6Y methyltransferase, CbiT subunit GO:0008276|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.196|MetaCyc: PWY-2201|MetaCyc: PWY-7377 CIG75_RS16925 b8b692a5f2971f2173d5d1d24383314b 404 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 8 185 1.1E-15 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CIG75_RS16925 b8b692a5f2971f2173d5d1d24383314b 404 Gene3D G3DSA:3.40.1010.10 2 109 1.6E-9 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CIG75_RS16925 b8b692a5f2971f2173d5d1d24383314b 404 Gene3D G3DSA:3.40.50.150 213 404 2.8E-27 T 28-03-2018 CIG75_RS16925 b8b692a5f2971f2173d5d1d24383314b 404 SUPERFAMILY SSF53790 5 199 1.25E-31 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CIG75_RS16925 b8b692a5f2971f2173d5d1d24383314b 404 PIRSF PIRSF036428 1 401 4.9E-115 T 28-03-2018 IPR006365 Cobalamin (vitamin B12) biosynthesis CobL/Precorrin-6Y C(5,15)-methyltransferase GO:0008276|GO:0009236 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|KEGG: 00860+2.1.1.132|MetaCyc: PWY-2201|MetaCyc: PWY-3841 CIG75_RS16925 b8b692a5f2971f2173d5d1d24383314b 404 TIGRFAM TIGR02467 CbiE: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit 7 197 1.0E-53 T 28-03-2018 IPR012818 Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase GO:0008276|GO:0009236 CIG75_RS18125 92ac9ddaca8d665cddba929e577c7b9d 103 SUPERFAMILY SSF54909 1 99 1.27E-22 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CIG75_RS18125 92ac9ddaca8d665cddba929e577c7b9d 103 Gene3D G3DSA:3.30.70.100 1 101 4.2E-19 T 28-03-2018 CIG75_RS18125 92ac9ddaca8d665cddba929e577c7b9d 103 Pfam PF07110 EthD domain 14 87 1.1E-5 T 28-03-2018 IPR009799 EthD domain CIG75_RS18125 92ac9ddaca8d665cddba929e577c7b9d 103 TIGRFAM TIGR02118 TIGR02118: conserved hypothetical protein 1 100 4.1E-24 T 28-03-2018 IPR009799 EthD domain CIG75_RS09685 7bf4e38712ff0054890d84aec1111528 1525 SUPERFAMILY SSF48452 853 959 7.02E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS09685 7bf4e38712ff0054890d84aec1111528 1525 SUPERFAMILY SSF55073 1360 1515 3.53E-42 T 28-03-2018 IPR029787 Nucleotide cyclase CIG75_RS09685 7bf4e38712ff0054890d84aec1111528 1525 Gene3D G3DSA:3.30.70.270 1351 1518 3.8E-48 T 28-03-2018 CIG75_RS09685 7bf4e38712ff0054890d84aec1111528 1525 SUPERFAMILY SSF52540 280 522 1.35E-8 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS09685 7bf4e38712ff0054890d84aec1111528 1525 SMART SM00220 13 254 5.1E-5 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CIG75_RS09685 7bf4e38712ff0054890d84aec1111528 1525 Gene3D G3DSA:1.25.40.10 502 830 1.6E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS09685 7bf4e38712ff0054890d84aec1111528 1525 Gene3D G3DSA:1.25.40.10 846 1186 1.3E-18 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS09685 7bf4e38712ff0054890d84aec1111528 1525 SMART SM00267 1345 1515 5.1E-46 T 28-03-2018 IPR000160 GGDEF domain CIG75_RS09685 7bf4e38712ff0054890d84aec1111528 1525 SUPERFAMILY SSF48452 1026 1141 6.08E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS09685 7bf4e38712ff0054890d84aec1111528 1525 Gene3D G3DSA:3.30.450.40 1216 1350 5.6E-5 T 28-03-2018 IPR029016 GAF domain-like CIG75_RS09685 7bf4e38712ff0054890d84aec1111528 1525 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 1355 1513 7.3E-45 T 28-03-2018 IPR000160 GGDEF domain CIG75_RS09685 7bf4e38712ff0054890d84aec1111528 1525 Gene3D G3DSA:1.10.510.10 70 260 8.7E-22 T 28-03-2018 CIG75_RS09685 7bf4e38712ff0054890d84aec1111528 1525 Gene3D G3DSA:3.40.50.300 273 495 3.0E-4 T 28-03-2018 CIG75_RS09685 7bf4e38712ff0054890d84aec1111528 1525 SUPERFAMILY SSF56112 12 254 1.08E-23 T 28-03-2018 IPR011009 Protein kinase-like domain CIG75_RS09685 7bf4e38712ff0054890d84aec1111528 1525 Pfam PF00069 Protein kinase domain 111 244 6.0E-9 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CIG75_RS09685 7bf4e38712ff0054890d84aec1111528 1525 SUPERFAMILY SSF55781 1300 1355 7.85E-6 T 28-03-2018 IPR029016 GAF domain-like CIG75_RS09685 7bf4e38712ff0054890d84aec1111528 1525 Pfam PF00990 Diguanylate cyclase, GGDEF domain 1357 1510 5.6E-40 T 28-03-2018 IPR000160 GGDEF domain CIG75_RS16900 336805bc25b6c482d10f7837519453cd 378 Gene3D G3DSA:3.90.1150.10 267 377 7.8E-18 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CIG75_RS16900 336805bc25b6c482d10f7837519453cd 378 Pfam PF00155 Aminotransferase class I and II 52 362 3.1E-34 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CIG75_RS16900 336805bc25b6c482d10f7837519453cd 378 Gene3D G3DSA:3.40.640.10 65 266 1.8E-33 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CIG75_RS16900 336805bc25b6c482d10f7837519453cd 378 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 232 245 - T 28-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CIG75_RS16900 336805bc25b6c482d10f7837519453cd 378 SUPERFAMILY SSF53383 34 371 1.73E-70 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CIG75_RS16900 336805bc25b6c482d10f7837519453cd 378 TIGRFAM TIGR01140 L_thr_O3P_dcar: threonine-phosphate decarboxylase 35 367 2.9E-97 T 28-03-2018 IPR005860 L-threonine-O-3-phosphate decarboxylase GO:0003824|GO:0009236 KEGG: 00860+4.1.1.81|MetaCyc: PWY-5443 CIG75_RS00030 7e1d4020f1213d2b8ac5fd95aa5945a0 109 SUPERFAMILY SSF54913 1 107 7.78E-13 T 28-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta CIG75_RS00030 7e1d4020f1213d2b8ac5fd95aa5945a0 109 Gene3D G3DSA:3.30.70.120 1 108 7.5E-14 T 28-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal CIG75_RS00030 7e1d4020f1213d2b8ac5fd95aa5945a0 109 Pfam PF06153 Cyclic-di-AMP receptor 1 109 1.0E-49 T 28-03-2018 IPR010375 Cyclic-di-AMP receptor CIG75_RS17060 1bdc1a4aad4b8634070ebabf1cd790cb 428 Hamap MF_00318 Enolase [eno]. 2 411 45.227 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CIG75_RS17060 1bdc1a4aad4b8634070ebabf1cd790cb 428 SUPERFAMILY SSF51604 138 425 1.02E-129 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CIG75_RS17060 1bdc1a4aad4b8634070ebabf1cd790cb 428 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 425 4.9E-213 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CIG75_RS17060 1bdc1a4aad4b8634070ebabf1cd790cb 428 SMART SM01192 139 425 9.9E-229 T 28-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CIG75_RS17060 1bdc1a4aad4b8634070ebabf1cd790cb 428 PIRSF PIRSF001400 1 425 1.0E-192 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CIG75_RS17060 1bdc1a4aad4b8634070ebabf1cd790cb 428 Pfam PF00113 Enolase, C-terminal TIM barrel domain 141 424 2.3E-135 T 28-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CIG75_RS17060 1bdc1a4aad4b8634070ebabf1cd790cb 428 PRINTS PR00148 Enolase signature 311 322 1.8E-46 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CIG75_RS17060 1bdc1a4aad4b8634070ebabf1cd790cb 428 PRINTS PR00148 Enolase signature 363 380 1.8E-46 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CIG75_RS17060 1bdc1a4aad4b8634070ebabf1cd790cb 428 PRINTS PR00148 Enolase signature 37 51 1.8E-46 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CIG75_RS17060 1bdc1a4aad4b8634070ebabf1cd790cb 428 PRINTS PR00148 Enolase signature 107 123 1.8E-46 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CIG75_RS17060 1bdc1a4aad4b8634070ebabf1cd790cb 428 PRINTS PR00148 Enolase signature 161 174 1.8E-46 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CIG75_RS17060 1bdc1a4aad4b8634070ebabf1cd790cb 428 PRINTS PR00148 Enolase signature 334 348 1.8E-46 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CIG75_RS17060 1bdc1a4aad4b8634070ebabf1cd790cb 428 Pfam PF03952 Enolase, N-terminal domain 4 134 4.9E-59 T 28-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CIG75_RS17060 1bdc1a4aad4b8634070ebabf1cd790cb 428 SMART SM01193 4 134 6.0E-92 T 28-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CIG75_RS17060 1bdc1a4aad4b8634070ebabf1cd790cb 428 Gene3D G3DSA:3.30.390.10 3 126 1.2E-51 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CIG75_RS17060 1bdc1a4aad4b8634070ebabf1cd790cb 428 ProSitePatterns PS00164 Enolase signature. 334 347 - T 28-03-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS17060 1bdc1a4aad4b8634070ebabf1cd790cb 428 SUPERFAMILY SSF54826 3 138 8.1E-58 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CIG75_RS17060 1bdc1a4aad4b8634070ebabf1cd790cb 428 Gene3D G3DSA:3.20.20.120 128 428 1.2E-103 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CIG75_RS05525 b8158420bf27b6f1c0901ecc6eed951e 1159 Gene3D G3DSA:2.40.50.140 955 1050 1.7E-12 T 28-03-2018 CIG75_RS05525 b8158420bf27b6f1c0901ecc6eed951e 1159 Pfam PF01336 OB-fold nucleic acid binding domain 974 1049 1.2E-10 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CIG75_RS05525 b8158420bf27b6f1c0901ecc6eed951e 1159 SMART SM00481 5 72 1.4E-23 T 28-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal CIG75_RS05525 b8158420bf27b6f1c0901ecc6eed951e 1159 Gene3D G3DSA:1.10.150.280 779 874 3.7E-6 T 28-03-2018 CIG75_RS05525 b8158420bf27b6f1c0901ecc6eed951e 1159 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 4 1011 0.0 T 28-03-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CIG75_RS05525 b8158420bf27b6f1c0901ecc6eed951e 1159 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 296 716 1.5E-172 T 28-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CIG75_RS05525 b8158420bf27b6f1c0901ecc6eed951e 1159 Gene3D G3DSA:3.20.20.140 3 260 3.2E-46 T 28-03-2018 CIG75_RS05525 b8158420bf27b6f1c0901ecc6eed951e 1159 Pfam PF14579 Helix-hairpin-helix motif 790 878 1.1E-28 T 28-03-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CIG75_RS05525 b8158420bf27b6f1c0901ecc6eed951e 1159 Pfam PF02811 PHP domain 6 177 1.2E-43 T 28-03-2018 IPR004013 PHP domain GO:0003824 CIG75_RS05525 b8158420bf27b6f1c0901ecc6eed951e 1159 SUPERFAMILY SSF89550 4 266 5.49E-21 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CIG75_RS15820 fcbfa1b695c4c1b32a41cb0e5da61b3b 251 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 23 231 4.9E-60 T 28-03-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 CIG75_RS02540 b9eefdb408072c94a569b80073c81343 286 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 58 100 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CIG75_RS02540 b9eefdb408072c94a569b80073c81343 286 Gene3D G3DSA:1.10.10.60 2 59 4.3E-12 T 28-03-2018 CIG75_RS02540 b9eefdb408072c94a569b80073c81343 286 Pfam PF12833 Helix-turn-helix domain 27 105 1.9E-17 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CIG75_RS02540 b9eefdb408072c94a569b80073c81343 286 SUPERFAMILY SSF46689 4 55 1.93E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CIG75_RS02540 b9eefdb408072c94a569b80073c81343 286 SMART SM00342 21 104 6.2E-23 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CIG75_RS02540 b9eefdb408072c94a569b80073c81343 286 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 73 88 3.8E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CIG75_RS02540 b9eefdb408072c94a569b80073c81343 286 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 88 104 3.8E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CIG75_RS02540 b9eefdb408072c94a569b80073c81343 286 SUPERFAMILY SSF55136 129 283 2.51E-21 T 28-03-2018 CIG75_RS02540 b9eefdb408072c94a569b80073c81343 286 Gene3D G3DSA:1.10.10.60 60 106 1.4E-9 T 28-03-2018 CIG75_RS02540 b9eefdb408072c94a569b80073c81343 286 Pfam PF06445 GyrI-like small molecule binding domain 129 280 1.7E-16 T 28-03-2018 IPR029442 GyrI-like small molecule binding domain CIG75_RS02540 b9eefdb408072c94a569b80073c81343 286 Gene3D G3DSA:3.20.80.10 127 282 6.4E-30 T 28-03-2018 IPR011256 Regulatory factor, effector binding domain CIG75_RS02540 b9eefdb408072c94a569b80073c81343 286 SUPERFAMILY SSF46689 58 108 2.6E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CIG75_RS02540 b9eefdb408072c94a569b80073c81343 286 SMART SM00871 128 281 6.0E-15 T 28-03-2018 IPR010499 Bacterial transcription activator, effector binding CIG75_RS10175 f09a3023dbfb74c90731617ee60b5350 212 SUPERFAMILY SSF55729 35 204 1.75E-32 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CIG75_RS10175 f09a3023dbfb74c90731617ee60b5350 212 Gene3D G3DSA:3.40.630.30 32 210 1.7E-24 T 28-03-2018 CIG75_RS10175 f09a3023dbfb74c90731617ee60b5350 212 Pfam PF13302 Acetyltransferase (GNAT) domain 38 180 1.6E-12 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CIG75_RS17560 f6d2998f7326251734c7b642784920d7 362 SUPERFAMILY SSF69572 97 361 7.85E-45 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CIG75_RS17560 f6d2998f7326251734c7b642784920d7 362 Pfam PF00899 ThiF family 123 350 3.3E-39 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CIG75_RS17560 f6d2998f7326251734c7b642784920d7 362 Gene3D G3DSA:3.40.50.720 93 361 6.5E-44 T 28-03-2018 CIG75_RS16480 0a64aa2dc3474235a8604d23c66fc4bd 207 Gene3D G3DSA:1.10.10.60 57 76 2.9E-10 T 28-03-2018 CIG75_RS16480 0a64aa2dc3474235a8604d23c66fc4bd 207 SUPERFAMILY SSF48498 92 206 8.01E-25 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CIG75_RS16480 0a64aa2dc3474235a8604d23c66fc4bd 207 Gene3D G3DSA:1.10.357.10 77 202 5.0E-20 T 28-03-2018 CIG75_RS16480 0a64aa2dc3474235a8604d23c66fc4bd 207 Pfam PF08359 YsiA-like protein, C-terminal region 72 204 3.0E-39 T 28-03-2018 IPR013570 Transcription regulator YsiA, C-terminal CIG75_RS16480 0a64aa2dc3474235a8604d23c66fc4bd 207 SUPERFAMILY SSF46689 13 86 9.22E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CIG75_RS16480 0a64aa2dc3474235a8604d23c66fc4bd 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 69 1.0E-15 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CIG75_RS16480 0a64aa2dc3474235a8604d23c66fc4bd 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 1.9E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CIG75_RS16480 0a64aa2dc3474235a8604d23c66fc4bd 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 1.9E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CIG75_RS16480 0a64aa2dc3474235a8604d23c66fc4bd 207 Gene3D G3DSA:1.10.10.60 12 56 1.8E-13 T 28-03-2018 CIG75_RS18790 bd11e480cf69353d05172777e359944c 379 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 201 365 1.4E-46 T 28-03-2018 IPR000160 GGDEF domain CIG75_RS18790 bd11e480cf69353d05172777e359944c 379 Gene3D G3DSA:3.30.70.270 198 376 2.0E-49 T 28-03-2018 CIG75_RS18790 bd11e480cf69353d05172777e359944c 379 Pfam PF00990 Diguanylate cyclase, GGDEF domain 205 364 2.2E-42 T 28-03-2018 IPR000160 GGDEF domain CIG75_RS18790 bd11e480cf69353d05172777e359944c 379 SUPERFAMILY SSF55073 210 369 3.61E-44 T 28-03-2018 IPR029787 Nucleotide cyclase CIG75_RS18790 bd11e480cf69353d05172777e359944c 379 SMART SM00267 194 368 3.4E-46 T 28-03-2018 IPR000160 GGDEF domain CIG75_RS17355 d3fc108966b98661a0b62c2d69ee1408 511 SMART SM01208 294 372 6.0E-16 T 28-03-2018 IPR011098 G5 domain CIG75_RS17355 d3fc108966b98661a0b62c2d69ee1408 511 Pfam PF01476 LysM domain 242 284 2.2E-7 T 28-03-2018 IPR018392 LysM domain CIG75_RS17355 d3fc108966b98661a0b62c2d69ee1408 511 Gene3D G3DSA:3.10.350.10 235 290 2.0E-12 T 28-03-2018 CIG75_RS17355 d3fc108966b98661a0b62c2d69ee1408 511 SUPERFAMILY SSF54106 240 285 1.1E-6 T 28-03-2018 IPR018392 LysM domain CIG75_RS17355 d3fc108966b98661a0b62c2d69ee1408 511 Gene3D G3DSA:2.20.230.10 293 376 1.4E-14 T 28-03-2018 CIG75_RS17355 d3fc108966b98661a0b62c2d69ee1408 511 SUPERFAMILY SSF51261 366 511 8.89E-51 T 28-03-2018 IPR011055 Duplicated hybrid motif CIG75_RS17355 d3fc108966b98661a0b62c2d69ee1408 511 Pfam PF07501 G5 domain 298 371 4.3E-17 T 28-03-2018 IPR011098 G5 domain CIG75_RS17355 d3fc108966b98661a0b62c2d69ee1408 511 Pfam PF01551 Peptidase family M23 412 507 6.8E-32 T 28-03-2018 IPR016047 Peptidase M23 CIG75_RS17355 d3fc108966b98661a0b62c2d69ee1408 511 Gene3D G3DSA:2.70.70.10 379 511 6.9E-40 T 28-03-2018 CIG75_RS17355 d3fc108966b98661a0b62c2d69ee1408 511 SMART SM00257 241 286 7.6E-6 T 28-03-2018 IPR018392 LysM domain CIG75_RS00665 719759d9133f8210d861c539916b0eac 585 Gene3D G3DSA:1.20.1560.10 1 315 1.1E-68 T 28-03-2018 CIG75_RS00665 719759d9133f8210d861c539916b0eac 585 SUPERFAMILY SSF52540 328 572 3.96E-85 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS00665 719759d9133f8210d861c539916b0eac 585 Gene3D G3DSA:3.40.50.300 316 577 6.2E-71 T 28-03-2018 CIG75_RS00665 719759d9133f8210d861c539916b0eac 585 SMART SM00382 361 569 1.4E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS00665 719759d9133f8210d861c539916b0eac 585 SUPERFAMILY SSF90123 4 317 7.98E-72 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CIG75_RS00665 719759d9133f8210d861c539916b0eac 585 Pfam PF00664 ABC transporter transmembrane region 17 285 1.1E-43 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CIG75_RS00665 719759d9133f8210d861c539916b0eac 585 Pfam PF00005 ABC transporter 352 501 3.1E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS00665 719759d9133f8210d861c539916b0eac 585 ProSitePatterns PS00211 ABC transporters family signature. 473 487 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS08420 bcc1a13f3dce642204556b0a571f15f8 327 SMART SM00861 4 179 5.9E-68 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CIG75_RS08420 bcc1a13f3dce642204556b0a571f15f8 327 Pfam PF02780 Transketolase, C-terminal domain 194 317 5.1E-44 T 28-03-2018 IPR033248 Transketolase, C-terminal domain CIG75_RS08420 bcc1a13f3dce642204556b0a571f15f8 327 Pfam PF02779 Transketolase, pyrimidine binding domain 5 178 8.5E-50 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CIG75_RS08420 bcc1a13f3dce642204556b0a571f15f8 327 SUPERFAMILY SSF52518 2 204 9.1E-73 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CIG75_RS08420 bcc1a13f3dce642204556b0a571f15f8 327 Gene3D G3DSA:3.40.50.920 195 326 1.3E-40 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CIG75_RS08420 bcc1a13f3dce642204556b0a571f15f8 327 Gene3D G3DSA:3.40.50.970 4 194 1.0E-69 T 28-03-2018 CIG75_RS08420 bcc1a13f3dce642204556b0a571f15f8 327 SUPERFAMILY SSF52922 189 326 3.53E-44 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CIG75_RS01020 6d13309f77bd650f20e98a8bb82a16c8 188 Pfam PF00881 Nitroreductase family 7 165 6.1E-30 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CIG75_RS01020 6d13309f77bd650f20e98a8bb82a16c8 188 PIRSF PIRSF000232 1 188 2.7E-51 T 28-03-2018 IPR026021 Putative NAD(P)H nitroreductase YdjA-like CIG75_RS01020 6d13309f77bd650f20e98a8bb82a16c8 188 SUPERFAMILY SSF55469 1 184 5.76E-39 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CIG75_RS01020 6d13309f77bd650f20e98a8bb82a16c8 188 Gene3D G3DSA:3.40.109.10 1 186 3.3E-40 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CIG75_RS06785 1d753c19caf8c37c46a52ff9c9751025 1145 SUPERFAMILY SSF56507 872 1145 5.1E-87 T 28-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CIG75_RS06785 1d753c19caf8c37c46a52ff9c9751025 1145 SUPERFAMILY SSF51717 338 600 1.11E-80 T 28-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CIG75_RS06785 1d753c19caf8c37c46a52ff9c9751025 1145 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 898 1145 1.5E-55 T 28-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CIG75_RS06785 1d753c19caf8c37c46a52ff9c9751025 1145 SUPERFAMILY SSF52242 707 847 9.29E-40 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CIG75_RS06785 1d753c19caf8c37c46a52ff9c9751025 1145 Gene3D G3DSA:3.20.20.20 326 616 3.1E-53 T 28-03-2018 CIG75_RS06785 1d753c19caf8c37c46a52ff9c9751025 1145 PIRSF PIRSF000381 1 1145 0.0 T 28-03-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CIG75_RS06785 1d753c19caf8c37c46a52ff9c9751025 1145 SUPERFAMILY SSF47644 622 706 1.44E-24 T 28-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CIG75_RS06785 1d753c19caf8c37c46a52ff9c9751025 1145 Gene3D G3DSA:3.20.20.330 2 320 9.4E-101 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CIG75_RS06785 1d753c19caf8c37c46a52ff9c9751025 1145 Pfam PF02574 Homocysteine S-methyltransferase 17 307 1.7E-76 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CIG75_RS06785 1d753c19caf8c37c46a52ff9c9751025 1145 Pfam PF02310 B12 binding domain 713 802 4.3E-19 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CIG75_RS06785 1d753c19caf8c37c46a52ff9c9751025 1145 Pfam PF02607 B12 binding domain 628 700 3.5E-23 T 28-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CIG75_RS06785 1d753c19caf8c37c46a52ff9c9751025 1145 TIGRFAM TIGR02082 metH: methionine synthase 13 1145 0.0 T 28-03-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CIG75_RS06785 1d753c19caf8c37c46a52ff9c9751025 1145 Pfam PF00809 Pterin binding enzyme 341 574 9.5E-43 T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CIG75_RS06785 1d753c19caf8c37c46a52ff9c9751025 1145 Gene3D G3DSA:3.40.50.280 701 857 6.5E-49 T 28-03-2018 CIG75_RS06785 1d753c19caf8c37c46a52ff9c9751025 1145 SMART SM01018 625 707 3.3E-39 T 28-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CIG75_RS06785 1d753c19caf8c37c46a52ff9c9751025 1145 Gene3D G3DSA:3.10.196.10 923 1145 1.4E-60 T 28-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CIG75_RS06785 1d753c19caf8c37c46a52ff9c9751025 1145 Gene3D G3DSA:1.10.1240.10 617 700 4.8E-30 T 28-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CIG75_RS06785 1d753c19caf8c37c46a52ff9c9751025 1145 SUPERFAMILY SSF82282 7 380 4.05E-113 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CIG75_RS15340 b493748439735324717e9336475c0b0a 422 Gene3D G3DSA:1.10.3210.10 7 312 2.6E-75 T 28-03-2018 CIG75_RS15340 b493748439735324717e9336475c0b0a 422 SUPERFAMILY SSF109604 5 403 1.35E-100 T 28-03-2018 CIG75_RS15340 b493748439735324717e9336475c0b0a 422 SMART SM00471 54 185 4.9E-11 T 28-03-2018 IPR003607 HD/PDEase domain CIG75_RS15340 b493748439735324717e9336475c0b0a 422 Pfam PF01966 HD domain 58 178 4.9E-12 T 28-03-2018 IPR006674 HD domain CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 SUPERFAMILY SSF52777 6495 6672 1.11E-44 T 28-03-2018 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 ProSitePatterns PS00012 Phosphopantetheine attachment site. 7487 7502 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 SUPERFAMILY SSF56801 3730 4286 5.76E-160 T 28-03-2018 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 SUPERFAMILY SSF52777 5427 5604 7.34E-48 T 28-03-2018 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 SUPERFAMILY SSF56801 5854 6417 3.27E-172 T 28-03-2018 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Gene3D G3DSA:3.40.50.980 6946 7102 2.7E-48 T 28-03-2018 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Gene3D G3DSA:3.40.50.980 6 173 4.7E-35 T 28-03-2018 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Gene3D G3DSA:3.40.50.980 5880 6035 6.3E-50 T 28-03-2018 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Gene3D G3DSA:3.40.50.980 4824 4978 1.7E-45 T 28-03-2018 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Gene3D G3DSA:3.40.50.980 3765 3918 6.6E-46 T 28-03-2018 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Gene3D G3DSA:3.40.50.980 1176 1331 1.3E-45 T 28-03-2018 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Gene3D G3DSA:3.40.50.980 2236 2391 1.9E-48 T 28-03-2018 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1714 1729 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 SUPERFAMILY SSF47336 1685 1756 1.31E-19 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Gene3D G3DSA:3.30.559.10 6472 6694 2.6E-42 T 28-03-2018 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Gene3D G3DSA:3.30.559.10 1765 1983 7.1E-44 T 28-03-2018 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Gene3D G3DSA:3.30.559.10 5405 5626 1.1E-47 T 28-03-2018 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Gene3D G3DSA:3.30.559.10 3289 3506 1.6E-43 T 28-03-2018 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Gene3D G3DSA:3.30.559.10 4344 4566 6.4E-47 T 28-03-2018 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 SUPERFAMILY SSF52777 1968 2207 3.11E-64 T 28-03-2018 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Pfam PF00501 AMP-binding enzyme 16 462 2.8E-82 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Pfam PF00501 AMP-binding enzyme 2245 2648 5.5E-102 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Pfam PF00501 AMP-binding enzyme 3774 4164 2.5E-100 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Pfam PF00501 AMP-binding enzyme 4834 5224 8.2E-99 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Pfam PF00501 AMP-binding enzyme 6955 7353 1.2E-92 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Pfam PF00501 AMP-binding enzyme 5889 6294 1.5E-110 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Pfam PF00501 AMP-binding enzyme 1185 1577 1.5E-98 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Gene3D G3DSA:1.10.1200.10 1696 1764 4.4E-24 T 28-03-2018 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Gene3D G3DSA:1.10.1200.10 4281 4343 3.5E-22 T 28-03-2018 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Gene3D G3DSA:1.10.1200.10 5341 5404 4.0E-22 T 28-03-2018 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Gene3D G3DSA:1.10.1200.10 6410 6471 1.6E-21 T 28-03-2018 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4299 4314 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 SUPERFAMILY SSF56801 2207 2767 6.67E-158 T 28-03-2018 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 SUPERFAMILY SSF52777 4367 4544 1.89E-46 T 28-03-2018 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Gene3D G3DSA:1.10.1200.10 593 689 6.6E-10 T 28-03-2018 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 SUPERFAMILY SSF47336 5327 5401 4.97E-21 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 SUPERFAMILY SSF47336 2750 2818 1.83E-17 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 SUPERFAMILY SSF52777 2834 3012 7.23E-37 T 28-03-2018 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 SUPERFAMILY SSF52777 5612 5856 8.89E-65 T 28-03-2018 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Gene3D G3DSA:3.30.300.30 4159 4280 1.2E-41 T 28-03-2018 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Gene3D G3DSA:3.30.300.30 6289 6409 1.1E-40 T 28-03-2018 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Gene3D G3DSA:3.30.300.30 7348 7468 2.9E-37 T 28-03-2018 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Gene3D G3DSA:3.30.300.30 1572 1695 1.1E-37 T 28-03-2018 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Gene3D G3DSA:3.30.300.30 2643 2761 4.7E-36 T 28-03-2018 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Gene3D G3DSA:3.30.300.30 5219 5340 2.4E-42 T 28-03-2018 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2386 2397 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 SUPERFAMILY SSF47336 6398 6469 4.19E-18 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 SUPERFAMILY SSF56801 8 565 2.22E-109 T 28-03-2018 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 SUPERFAMILY SSF52777 6677 6920 1.11E-62 T 28-03-2018 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 ProSitePatterns PS00012 Phosphopantetheine attachment site. 6428 6443 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 SUPERFAMILY SSF52777 893 1169 9.12E-52 T 28-03-2018 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 SUPERFAMILY SSF47336 606 688 2.62E-9 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 SUPERFAMILY SSF56801 4793 5348 5.76E-159 T 28-03-2018 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 SUPERFAMILY SSF52777 3318 3490 1.89E-45 T 28-03-2018 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 ProSitePatterns PS00455 Putative AMP-binding domain signature. 7097 7108 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 ProSitePatterns PS00012 Phosphopantetheine attachment site. 5359 5374 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Gene3D G3DSA:1.10.1200.10 2762 2828 7.1E-20 T 28-03-2018 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Gene3D G3DSA:1.10.1200.10 7469 7545 9.5E-22 T 28-03-2018 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 3146 3297 1.9E-40 T 28-03-2018 IPR010060 Non-ribosomal peptide synthase CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Pfam PF00550 Phosphopantetheine attachment site 6407 6468 4.6E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Pfam PF00550 Phosphopantetheine attachment site 2757 2818 1.2E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Pfam PF00550 Phosphopantetheine attachment site 4279 4340 2.8E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Pfam PF00550 Phosphopantetheine attachment site 7465 7528 2.3E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Pfam PF00550 Phosphopantetheine attachment site 5338 5400 2.0E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Pfam PF00550 Phosphopantetheine attachment site 1693 1755 5.7E-17 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Pfam PF00550 Phosphopantetheine attachment site 616 677 1.9E-7 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 SUPERFAMILY SSF52777 4552 4818 4.34E-63 T 28-03-2018 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 3794 4188 1.6E-127 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 6976 7377 5.1E-119 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 5910 6318 1.0E-141 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 4854 5248 4.8E-126 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2266 2672 3.1E-140 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1206 1600 3.8E-131 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 ProSitePatterns PS00455 Putative AMP-binding domain signature. 3913 3924 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1326 1337 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Gene3D G3DSA:3.40.50.980 4979 5125 3.0E-31 T 28-03-2018 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Gene3D G3DSA:3.40.50.980 174 345 3.0E-32 T 28-03-2018 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Gene3D G3DSA:3.40.50.980 7103 7265 1.6E-31 T 28-03-2018 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Gene3D G3DSA:3.40.50.980 6036 6201 1.2E-41 T 28-03-2018 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Gene3D G3DSA:3.40.50.980 2392 2554 2.6E-35 T 28-03-2018 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Gene3D G3DSA:3.40.50.980 3919 4065 1.4E-31 T 28-03-2018 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Gene3D G3DSA:3.40.50.980 1332 1486 7.0E-32 T 28-03-2018 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 ProSitePatterns PS00455 Putative AMP-binding domain signature. 6030 6041 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Gene3D G3DSA:3.30.559.10 690 881 1.8E-28 T 28-03-2018 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Gene3D G3DSA:3.30.559.10 2829 3029 6.3E-30 T 28-03-2018 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 SMART SM00823 Phosphopantetheine attachment site 6404 6473 0.0043 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 SMART SM00823 Phosphopantetheine attachment site 613 684 1.4E-8 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 SMART SM00823 Phosphopantetheine attachment site 5335 5404 9.4E-4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 SMART SM00823 Phosphopantetheine attachment site 2756 2824 0.0014 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 SMART SM00823 Phosphopantetheine attachment site 1690 1759 1.1E-6 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 SMART SM00823 Phosphopantetheine attachment site 7463 7532 9.7E-4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 SMART SM00823 Phosphopantetheine attachment site 4275 4344 0.0031 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 SUPERFAMILY SSF52777 3491 3759 3.11E-54 T 28-03-2018 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 SUPERFAMILY SSF56801 6915 7475 1.16E-149 T 28-03-2018 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Pfam PF00668 Condensation domain 3313 3751 6.7E-94 T 28-03-2018 IPR001242 Condensation domain CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Pfam PF00668 Condensation domain 4364 4808 4.1E-115 T 28-03-2018 IPR001242 Condensation domain CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Pfam PF00668 Condensation domain 2838 3290 1.2E-78 T 28-03-2018 IPR001242 Condensation domain CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Pfam PF00668 Condensation domain 6491 6934 6.6E-119 T 28-03-2018 IPR001242 Condensation domain CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Pfam PF00668 Condensation domain 5424 5869 2.6E-118 T 28-03-2018 IPR001242 Condensation domain CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Pfam PF00668 Condensation domain 1779 2224 1.1E-115 T 28-03-2018 IPR001242 Condensation domain CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Pfam PF00668 Condensation domain 714 1163 3.8E-89 T 28-03-2018 IPR001242 Condensation domain CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 SUPERFAMILY SSF52777 1783 1960 2.33E-47 T 28-03-2018 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 SUPERFAMILY SSF47336 4267 4341 3.93E-20 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Gene3D G3DSA:3.30.300.30 455 563 1.7E-12 T 28-03-2018 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 SUPERFAMILY SSF52777 3024 3271 8.15E-43 T 28-03-2018 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 SUPERFAMILY SSF52777 708 885 7.56E-33 T 28-03-2018 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Pfam PF13193 AMP-binding enzyme C-terminal domain 4172 4248 3.0E-12 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Pfam PF13193 AMP-binding enzyme C-terminal domain 1585 1663 4.0E-13 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Pfam PF13193 AMP-binding enzyme C-terminal domain 5232 5308 1.8E-12 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Pfam PF13193 AMP-binding enzyme C-terminal domain 7361 7436 2.1E-8 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Pfam PF13193 AMP-binding enzyme C-terminal domain 6302 6377 3.2E-14 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Pfam PF13193 AMP-binding enzyme C-terminal domain 2656 2729 3.7E-6 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 SUPERFAMILY SSF47336 7456 7528 6.41E-18 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2780 2795 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Gene3D G3DSA:2.30.38.10 1487 1567 7.9E-23 T 28-03-2018 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 SUPERFAMILY SSF56801 1143 1703 1.44E-155 T 28-03-2018 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 ProSitePatterns PS00455 Putative AMP-binding domain signature. 4973 4984 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Gene3D G3DSA:2.30.38.10 4066 4156 2.8E-23 T 28-03-2018 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Gene3D G3DSA:2.30.38.10 5126 5216 6.4E-23 T 28-03-2018 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Gene3D G3DSA:2.30.38.10 2557 2641 7.0E-24 T 28-03-2018 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Gene3D G3DSA:2.30.38.10 7267 7346 1.9E-20 T 28-03-2018 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Gene3D G3DSA:2.30.38.10 371 454 3.8E-16 T 28-03-2018 CIG75_RS10345 71eb8a3f6d345132c7ba163dfe2688b9 7554 Gene3D G3DSA:2.30.38.10 6203 6287 1.2E-24 T 28-03-2018 CIG75_RS19900 07ace792e4ed0108ca6a9a8e23363cd1 238 Gene3D G3DSA:3.40.50.1000 80 235 2.1E-26 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS19900 07ace792e4ed0108ca6a9a8e23363cd1 238 Gene3D G3DSA:3.40.50.1000 5 59 5.7E-6 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS19900 07ace792e4ed0108ca6a9a8e23363cd1 238 Pfam PF13419 Haloacid dehalogenase-like hydrolase 14 197 3.6E-26 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS19900 07ace792e4ed0108ca6a9a8e23363cd1 238 SUPERFAMILY SSF56784 9 228 3.82E-44 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS19900 07ace792e4ed0108ca6a9a8e23363cd1 238 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 101 191 4.0E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CIG75_RS06320 d14b989dcb278b0ba59089e43929773b 331 Gene3D G3DSA:3.40.50.300 18 181 2.0E-29 T 28-03-2018 CIG75_RS06320 d14b989dcb278b0ba59089e43929773b 331 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 253 326 1.8E-35 T 28-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 CIG75_RS06320 d14b989dcb278b0ba59089e43929773b 331 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 9 235 3.7E-116 T 28-03-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 CIG75_RS06320 d14b989dcb278b0ba59089e43929773b 331 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 250 330 4.0E-30 T 28-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 CIG75_RS06320 d14b989dcb278b0ba59089e43929773b 331 SUPERFAMILY SSF46785 257 330 1.81E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS06320 d14b989dcb278b0ba59089e43929773b 331 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 24 326 2.4E-145 T 28-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 CIG75_RS06320 d14b989dcb278b0ba59089e43929773b 331 Gene3D G3DSA:1.10.10.10 257 327 1.7E-35 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS06320 d14b989dcb278b0ba59089e43929773b 331 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 331 173.231 T 28-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 CIG75_RS06320 d14b989dcb278b0ba59089e43929773b 331 SMART SM00382 51 182 9.6E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS06320 d14b989dcb278b0ba59089e43929773b 331 Gene3D G3DSA:1.10.8.60 184 254 2.7E-30 T 28-03-2018 CIG75_RS06320 d14b989dcb278b0ba59089e43929773b 331 SUPERFAMILY SSF52540 18 253 1.24E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS14835 44a965d0caba2cf8ec2a26a41621d8fe 316 Pfam PF12705 PD-(D/E)XK nuclease superfamily 16 311 7.7E-17 T 28-03-2018 CIG75_RS14835 44a965d0caba2cf8ec2a26a41621d8fe 316 Gene3D G3DSA:3.90.320.10 55 247 3.5E-9 T 28-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 CIG75_RS09115 9818af300bdad4a7c0874a04c8e793ef 66 SUPERFAMILY SSF50249 1 64 1.93E-25 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CIG75_RS09115 9818af300bdad4a7c0874a04c8e793ef 66 PRINTS PR00050 Cold shock protein signature 24 33 1.8E-18 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CIG75_RS09115 9818af300bdad4a7c0874a04c8e793ef 66 PRINTS PR00050 Cold shock protein signature 39 57 1.8E-18 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CIG75_RS09115 9818af300bdad4a7c0874a04c8e793ef 66 PRINTS PR00050 Cold shock protein signature 3 18 1.8E-18 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CIG75_RS09115 9818af300bdad4a7c0874a04c8e793ef 66 SMART SM00357 2 66 5.4E-31 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 CIG75_RS09115 9818af300bdad4a7c0874a04c8e793ef 66 PIRSF PIRSF002599 1 66 1.6E-24 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 CIG75_RS09115 9818af300bdad4a7c0874a04c8e793ef 66 Gene3D G3DSA:2.40.50.140 1 66 1.1E-28 T 28-03-2018 CIG75_RS09115 9818af300bdad4a7c0874a04c8e793ef 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 14 33 - T 28-03-2018 IPR019844 Cold-shock conserved site CIG75_RS09115 9818af300bdad4a7c0874a04c8e793ef 66 Pfam PF00313 'Cold-shock' DNA-binding domain 1 65 1.2E-31 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CIG75_RS08760 8894f336fad4a64305c3399b172766e2 361 Gene3D G3DSA:3.40.140.10 1 118 3.1E-31 T 28-03-2018 CIG75_RS08760 8894f336fad4a64305c3399b172766e2 361 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 140 354 1.4E-67 T 28-03-2018 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 CIG75_RS08760 8894f336fad4a64305c3399b172766e2 361 SUPERFAMILY SSF53927 1 136 8.84E-45 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CIG75_RS08760 8894f336fad4a64305c3399b172766e2 361 SUPERFAMILY SSF53597 139 356 1.21E-66 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CIG75_RS08760 8894f336fad4a64305c3399b172766e2 361 Pfam PF01872 RibD C-terminal domain 141 352 4.8E-57 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CIG75_RS08760 8894f336fad4a64305c3399b172766e2 361 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 1 352 1.7E-122 T 28-03-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 CIG75_RS08760 8894f336fad4a64305c3399b172766e2 361 Gene3D G3DSA:3.40.430.10 119 360 7.4E-84 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CIG75_RS08760 8894f336fad4a64305c3399b172766e2 361 PIRSF PIRSF006769 1 359 2.7E-139 T 28-03-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 CIG75_RS08760 8894f336fad4a64305c3399b172766e2 361 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 1 94 5.9E-18 T 28-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain CIG75_RS01645 3aa488f8f170fe330fe49c5cb9c9ecff 844 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 622 807 2.5E-34 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CIG75_RS01645 3aa488f8f170fe330fe49c5cb9c9ecff 844 SUPERFAMILY SSF81606 595 808 2.62E-23 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CIG75_RS01645 3aa488f8f170fe330fe49c5cb9c9ecff 844 SMART SM00331 595 807 2.8E-37 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CIG75_RS01645 3aa488f8f170fe330fe49c5cb9c9ecff 844 TIGRFAM TIGR02865 spore_II_E: stage II sporulation protein E 48 807 5.1E-230 T 28-03-2018 IPR014221 Sporulation stage II, protein E KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CIG75_RS01645 3aa488f8f170fe330fe49c5cb9c9ecff 844 Gene3D G3DSA:3.60.40.10 586 816 2.2E-27 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CIG75_RS01645 3aa488f8f170fe330fe49c5cb9c9ecff 844 SMART SM00332 587 805 5.1E-4 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CIG75_RS09925 de60372d089d39dbfc3e18635f7c641e 223 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 64 77 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS09925 de60372d089d39dbfc3e18635f7c641e 223 Pfam PF04542 Sigma-70 region 2 45 107 1.2E-12 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS09925 de60372d089d39dbfc3e18635f7c641e 223 PIRSF PIRSF002939 6 220 1.0E-72 T 28-03-2018 IPR016371 RNA polymerase sigma-H factor GO:0003677|GO:0006351|GO:0016987 CIG75_RS09925 de60372d089d39dbfc3e18635f7c641e 223 SUPERFAMILY SSF88946 10 106 3.4E-21 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS09925 de60372d089d39dbfc3e18635f7c641e 223 Pfam PF08281 Sigma-70, region 4 163 209 3.8E-8 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS09925 de60372d089d39dbfc3e18635f7c641e 223 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 36 210 1.3E-22 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS09925 de60372d089d39dbfc3e18635f7c641e 223 Gene3D G3DSA:1.10.1740.10 24 107 2.5E-18 T 28-03-2018 CIG75_RS09925 de60372d089d39dbfc3e18635f7c641e 223 Gene3D G3DSA:1.10.10.10 150 222 8.7E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS09925 de60372d089d39dbfc3e18635f7c641e 223 SUPERFAMILY SSF88659 127 213 1.12E-9 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS17830 237c12be014aaa4a3795e88ba04deeef 296 SUPERFAMILY SSF54001 110 261 4.71E-5 T 28-03-2018 CIG75_RS17830 237c12be014aaa4a3795e88ba04deeef 296 Gene3D G3DSA:3.90.70.10 97 286 1.8E-13 T 28-03-2018 CIG75_RS17830 237c12be014aaa4a3795e88ba04deeef 296 Pfam PF13529 Peptidase_C39 like family 114 261 1.1E-11 T 28-03-2018 CIG75_RS11950 1833ba5598e1c5799ed86c39e4ae31a6 353 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 4 352 40.071 T 28-03-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CIG75_RS11950 1833ba5598e1c5799ed86c39e4ae31a6 353 PIRSF PIRSF000876 1 353 2.6E-134 T 28-03-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CIG75_RS11950 1833ba5598e1c5799ed86c39e4ae31a6 353 SMART SM00448 4 118 7.5E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CIG75_RS11950 1833ba5598e1c5799ed86c39e4ae31a6 353 SUPERFAMILY SSF52738 163 352 2.48E-68 T 28-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CIG75_RS11950 1833ba5598e1c5799ed86c39e4ae31a6 353 SUPERFAMILY SSF52172 1 117 9.96E-29 T 28-03-2018 IPR011006 CheY-like superfamily CIG75_RS11950 1833ba5598e1c5799ed86c39e4ae31a6 353 Gene3D G3DSA:3.40.50.2300 3 146 5.2E-29 T 28-03-2018 CIG75_RS11950 1833ba5598e1c5799ed86c39e4ae31a6 353 Gene3D G3DSA:3.40.50.180 156 353 6.2E-79 T 28-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CIG75_RS11950 1833ba5598e1c5799ed86c39e4ae31a6 353 Pfam PF00072 Response regulator receiver domain 6 113 2.6E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CIG75_RS11950 1833ba5598e1c5799ed86c39e4ae31a6 353 Pfam PF01339 CheB methylesterase 167 347 7.7E-65 T 28-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CIG75_RS08180 ce3c7d043bf74930be474f244bfe3dcb 152 Pfam PF07963 Prokaryotic N-terminal methylation motif 6 30 2.4E-6 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site CIG75_RS08180 ce3c7d043bf74930be474f244bfe3dcb 152 SUPERFAMILY SSF54523 12 87 1.33E-7 T 28-03-2018 CIG75_RS08180 ce3c7d043bf74930be474f244bfe3dcb 152 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 8 30 4.2E-6 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site CIG75_RS08180 ce3c7d043bf74930be474f244bfe3dcb 152 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 9 29 - T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site CIG75_RS08180 ce3c7d043bf74930be474f244bfe3dcb 152 Gene3D G3DSA:3.30.700.10 11 142 9.3E-5 T 28-03-2018 CIG75_RS05340 08744e2fe4c605016999136ba4171c99 644 Pfam PF00694 Aconitase C-terminal domain 520 577 1.6E-24 T 28-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 CIG75_RS05340 08744e2fe4c605016999136ba4171c99 644 Gene3D G3DSA:3.30.499.10 1 146 5.2E-43 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CIG75_RS05340 08744e2fe4c605016999136ba4171c99 644 Gene3D G3DSA:3.40.1060.10 147 269 7.0E-40 T 28-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 CIG75_RS05340 08744e2fe4c605016999136ba4171c99 644 Gene3D G3DSA:3.20.19.10 519 644 3.0E-43 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CIG75_RS05340 08744e2fe4c605016999136ba4171c99 644 SUPERFAMILY SSF53732 1 420 3.53E-147 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CIG75_RS05340 08744e2fe4c605016999136ba4171c99 644 Pfam PF00330 Aconitase family (aconitate hydratase) 7 409 3.0E-114 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CIG75_RS05340 08744e2fe4c605016999136ba4171c99 644 TIGRFAM TIGR01342 acon_putative: putative aconitate hydratase 5 642 1.3E-293 T 28-03-2018 IPR006250 Aconitase, putative CIG75_RS05340 08744e2fe4c605016999136ba4171c99 644 Gene3D G3DSA:3.30.499.10 270 438 1.4E-51 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CIG75_RS05340 08744e2fe4c605016999136ba4171c99 644 PRINTS PR00415 Aconitase family signature 110 123 1.9E-29 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CIG75_RS05340 08744e2fe4c605016999136ba4171c99 644 PRINTS PR00415 Aconitase family signature 186 199 1.9E-29 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CIG75_RS05340 08744e2fe4c605016999136ba4171c99 644 PRINTS PR00415 Aconitase family signature 351 364 1.9E-29 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CIG75_RS05340 08744e2fe4c605016999136ba4171c99 644 PRINTS PR00415 Aconitase family signature 200 213 1.9E-29 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CIG75_RS05340 08744e2fe4c605016999136ba4171c99 644 PRINTS PR00415 Aconitase family signature 90 98 1.9E-29 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CIG75_RS05340 08744e2fe4c605016999136ba4171c99 644 PRINTS PR00415 Aconitase family signature 124 139 1.9E-29 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CIG75_RS05340 08744e2fe4c605016999136ba4171c99 644 PRINTS PR00415 Aconitase family signature 295 306 1.9E-29 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CIG75_RS05340 08744e2fe4c605016999136ba4171c99 644 SUPERFAMILY SSF52016 439 642 2.75E-59 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CIG75_RS05340 08744e2fe4c605016999136ba4171c99 644 ProSitePatterns PS00450 Aconitase family signature 1. 291 307 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CIG75_RS05340 08744e2fe4c605016999136ba4171c99 644 Gene3D G3DSA:3.20.19.10 459 518 1.7E-12 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CIG75_RS05340 08744e2fe4c605016999136ba4171c99 644 ProSitePatterns PS01244 Aconitase family signature 2. 351 364 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CIG75_RS19635 b287b9570a0aeafb67c9c3ff604b6407 427 ProSitePatterns PS00755 Protein secY signature 1. 68 87 - T 28-03-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CIG75_RS19635 b287b9570a0aeafb67c9c3ff604b6407 427 ProSitePatterns PS00756 Protein secY signature 2. 164 181 - T 28-03-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CIG75_RS19635 b287b9570a0aeafb67c9c3ff604b6407 427 PIRSF PIRSF004557 1 427 2.0E-120 T 28-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CIG75_RS19635 b287b9570a0aeafb67c9c3ff604b6407 427 SUPERFAMILY SSF103491 1 416 2.62E-125 T 28-03-2018 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CIG75_RS19635 b287b9570a0aeafb67c9c3ff604b6407 427 PRINTS PR00303 Preprotein translocase SecY subunit signature 18 36 5.6E-96 T 28-03-2018 CIG75_RS19635 b287b9570a0aeafb67c9c3ff604b6407 427 PRINTS PR00303 Preprotein translocase SecY subunit signature 307 329 5.6E-96 T 28-03-2018 CIG75_RS19635 b287b9570a0aeafb67c9c3ff604b6407 427 PRINTS PR00303 Preprotein translocase SecY subunit signature 145 170 5.6E-96 T 28-03-2018 CIG75_RS19635 b287b9570a0aeafb67c9c3ff604b6407 427 PRINTS PR00303 Preprotein translocase SecY subunit signature 171 194 5.6E-96 T 28-03-2018 CIG75_RS19635 b287b9570a0aeafb67c9c3ff604b6407 427 PRINTS PR00303 Preprotein translocase SecY subunit signature 67 87 5.6E-96 T 28-03-2018 CIG75_RS19635 b287b9570a0aeafb67c9c3ff604b6407 427 PRINTS PR00303 Preprotein translocase SecY subunit signature 109 132 5.6E-96 T 28-03-2018 CIG75_RS19635 b287b9570a0aeafb67c9c3ff604b6407 427 PRINTS PR00303 Preprotein translocase SecY subunit signature 362 380 5.6E-96 T 28-03-2018 CIG75_RS19635 b287b9570a0aeafb67c9c3ff604b6407 427 PRINTS PR00303 Preprotein translocase SecY subunit signature 267 286 5.6E-96 T 28-03-2018 CIG75_RS19635 b287b9570a0aeafb67c9c3ff604b6407 427 PRINTS PR00303 Preprotein translocase SecY subunit signature 394 412 5.6E-96 T 28-03-2018 CIG75_RS19635 b287b9570a0aeafb67c9c3ff604b6407 427 Gene3D G3DSA:1.10.3370.10 1 427 6.2E-160 T 28-03-2018 CIG75_RS19635 b287b9570a0aeafb67c9c3ff604b6407 427 Hamap MF_01465 Protein translocase subunit SecY [secY]. 5 425 30.101 T 28-03-2018 IPR026593 Protein translocase subunit SecY CIG75_RS19635 b287b9570a0aeafb67c9c3ff604b6407 427 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 15 421 1.1E-131 T 28-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CIG75_RS19635 b287b9570a0aeafb67c9c3ff604b6407 427 Pfam PF00344 SecY translocase 68 409 9.7E-114 T 28-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CIG75_RS04585 1b43ab6d30dd3df732ef792587628654 419 SUPERFAMILY SSF103473 11 408 2.09E-45 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS04585 1b43ab6d30dd3df732ef792587628654 419 Pfam PF07690 Major Facilitator Superfamily 33 368 8.2E-35 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CIG75_RS04585 1b43ab6d30dd3df732ef792587628654 419 Gene3D G3DSA:1.20.1250.20 207 412 3.3E-16 T 28-03-2018 CIG75_RS04585 1b43ab6d30dd3df732ef792587628654 419 Gene3D G3DSA:1.20.1250.20 1 205 1.4E-24 T 28-03-2018 CIG75_RS05655 1c3ddae8cb9c18519f7b97c7fd149270 46 SUPERFAMILY SSF100985 1 43 4.84E-11 T 28-03-2018 IPR015064 Sporulation inhibitor A CIG75_RS05655 1c3ddae8cb9c18519f7b97c7fd149270 46 Gene3D G3DSA:1.10.287.1100 4 36 6.4E-12 T 28-03-2018 IPR015064 Sporulation inhibitor A CIG75_RS05655 1c3ddae8cb9c18519f7b97c7fd149270 46 Pfam PF08970 Sporulation inhibitor A 1 41 2.6E-12 T 28-03-2018 IPR015064 Sporulation inhibitor A CIG75_RS12020 03cca479462ad3386d8e3a53867756b1 268 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 186 266 1.2E-22 T 28-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain CIG75_RS12020 03cca479462ad3386d8e3a53867756b1 268 Pfam PF00460 Flagella basal body rod protein 5 35 3.2E-11 T 28-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 CIG75_RS12020 03cca479462ad3386d8e3a53867756b1 268 TIGRFAM TIGR02490 flgF: flagellar basal-body rod protein FlgF 5 247 1.3E-55 T 28-03-2018 IPR012836 Flagellar basal-body rod FlgF GO:0030694|GO:0071973 CIG75_RS12020 03cca479462ad3386d8e3a53867756b1 268 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 151 249 1.4E-26 T 28-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G CIG75_RS12020 03cca479462ad3386d8e3a53867756b1 268 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 3 135 1.9E-41 T 28-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G CIG75_RS12020 03cca479462ad3386d8e3a53867756b1 268 SUPERFAMILY SSF117143 91 228 1.96E-34 T 28-03-2018 CIG75_RS11440 121bb3e10ac4aadb8d7296de5da9232d 562 Gene3D G3DSA:3.40.50.300 395 555 1.3E-21 T 28-03-2018 CIG75_RS11440 121bb3e10ac4aadb8d7296de5da9232d 562 SMART SM00487 188 362 3.4E-23 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CIG75_RS11440 121bb3e10ac4aadb8d7296de5da9232d 562 SMART SM00490 427 514 7.3E-12 T 28-03-2018 IPR001650 Helicase, C-terminal CIG75_RS11440 121bb3e10ac4aadb8d7296de5da9232d 562 SUPERFAMILY SSF52540 210 343 1.17E-33 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS11440 121bb3e10ac4aadb8d7296de5da9232d 562 SUPERFAMILY SSF52540 392 524 1.17E-33 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS11440 121bb3e10ac4aadb8d7296de5da9232d 562 Pfam PF16203 ERCC3/RAD25/XPB C-terminal helicase 368 554 1.5E-45 T 28-03-2018 IPR032438 ERCC3/RAD25/XPB helicase, C-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 CIG75_RS11440 121bb3e10ac4aadb8d7296de5da9232d 562 Gene3D G3DSA:3.40.50.300 180 368 5.4E-28 T 28-03-2018 CIG75_RS11440 121bb3e10ac4aadb8d7296de5da9232d 562 Pfam PF13625 Helicase conserved C-terminal domain 14 135 2.3E-29 T 28-03-2018 IPR032830 Helicase XPB/Ssl2, N-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 CIG75_RS11440 121bb3e10ac4aadb8d7296de5da9232d 562 Pfam PF04851 Type III restriction enzyme, res subunit 191 340 1.4E-16 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 SMART SM01294 1707 1764 0.0055 T 28-03-2018 CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 SUPERFAMILY SSF52777 1790 1967 1.45E-49 T 28-03-2018 CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 SUPERFAMILY SSF52777 3970 4147 4.56E-52 T 28-03-2018 CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 Gene3D G3DSA:2.30.38.10 392 464 8.0E-20 T 28-03-2018 CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 Pfam PF13193 AMP-binding enzyme C-terminal domain 3776 3850 2.4E-9 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 Pfam PF13193 AMP-binding enzyme C-terminal domain 4847 4921 2.7E-7 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 Pfam PF13193 AMP-binding enzyme C-terminal domain 2692 2765 1.6E-8 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 Pfam PF13193 AMP-binding enzyme C-terminal domain 1596 1670 3.7E-11 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2417 2428 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 Gene3D G3DSA:2.30.38.10 1498 1581 1.2E-23 T 28-03-2018 CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2279 2708 8.3E-125 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 4457 4863 9.7E-134 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 3366 3792 3.6E-129 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1185 1612 2.8E-123 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3903 3918 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 SUPERFAMILY SSF47336 2786 2896 2.22E-21 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 5417 5468 2.5E-11 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 Pfam PF00668 Condensation domain 3965 4412 2.7E-122 T 28-03-2018 IPR001242 Condensation domain CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 Pfam PF00668 Condensation domain 700 1140 4.9E-103 T 28-03-2018 IPR001242 Condensation domain CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 Pfam PF00668 Condensation domain 1784 2230 2.3E-115 T 28-03-2018 IPR001242 Condensation domain CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 Pfam PF00668 Condensation domain 2880 3324 1.1E-119 T 28-03-2018 IPR001242 Condensation domain CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 SUPERFAMILY SSF47336 1693 1801 4.84E-20 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 SUPERFAMILY SSF52777 4153 4400 1.45E-56 T 28-03-2018 CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 SUPERFAMILY SSF47336 3872 3981 2.09E-22 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 SUPERFAMILY SSF56801 15 360 5.23E-102 T 28-03-2018 CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 SUPERFAMILY SSF56801 387 609 5.23E-102 T 28-03-2018 CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 SUPERFAMILY SSF52777 893 1133 2.22E-55 T 28-03-2018 CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 SUPERFAMILY SSF56801 3305 3887 5.63E-159 T 28-03-2018 CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 SMART SM00823 Phosphopantetheine attachment site 4949 5019 9.4E-4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 SMART SM00823 Phosphopantetheine attachment site 3879 3948 6.3E-8 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 SMART SM00823 Phosphopantetheine attachment site 1699 1768 3.9E-10 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 SMART SM00823 Phosphopantetheine attachment site 2794 2863 0.0025 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 SMART SM00823 Phosphopantetheine attachment site 602 674 3.5E-4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 ProSitePatterns PS00455 Putative AMP-binding domain signature. 186 197 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 SUPERFAMILY SSF56801 1135 1712 2.09E-157 T 28-03-2018 CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 SUPERFAMILY SSF53901 5037 5156 1.33E-84 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 SUPERFAMILY SSF53901 5183 5410 1.33E-84 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 SUPERFAMILY SSF53901 5442 5462 1.33E-84 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 Gene3D G3DSA:3.30.559.10 3956 4151 3.0E-44 T 28-03-2018 CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 Gene3D G3DSA:3.30.559.10 2880 3070 7.3E-41 T 28-03-2018 CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 Gene3D G3DSA:3.30.559.10 681 905 4.3E-38 T 28-03-2018 CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 Gene3D G3DSA:3.30.559.10 1783 1989 4.7E-42 T 28-03-2018 CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 ProSitePatterns PS00455 Putative AMP-binding domain signature. 4575 4586 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 Gene3D G3DSA:1.10.1200.10 2800 2879 1.5E-22 T 28-03-2018 CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 Gene3D G3DSA:1.10.1200.10 4954 5037 5.2E-21 T 28-03-2018 CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 Gene3D G3DSA:1.10.1200.10 1705 1782 1.1E-22 T 28-03-2018 CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 SUPERFAMILY SSF52777 3069 3332 8.89E-61 T 28-03-2018 CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 SUPERFAMILY SSF47336 4941 5052 5.5E-19 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 SMART SM00825 Beta-ketoacyl synthase 5042 5467 1.3E-174 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1325 1336 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 SUPERFAMILY SSF47336 596 673 6.67E-17 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 5040 5288 1.1E-66 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 Gene3D G3DSA:3.40.47.10 5303 5465 2.2E-58 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 SUPERFAMILY SSF56801 4415 4962 7.06E-156 T 28-03-2018 CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2818 2833 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 Gene3D G3DSA:3.40.47.10 5038 5300 7.5E-62 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 SUPERFAMILY SSF52777 2885 3062 4.11E-49 T 28-03-2018 CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 Gene3D G3DSA:1.10.1200.10 3885 3955 6.6E-25 T 28-03-2018 CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 Gene3D G3DSA:1.10.1200.10 608 680 3.0E-19 T 28-03-2018 CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 5201 5217 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 SUPERFAMILY SSF56801 2251 2807 1.44E-154 T 28-03-2018 CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 Gene3D G3DSA:3.30.300.30 2680 2799 1.4E-36 T 28-03-2018 CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 Gene3D G3DSA:3.30.300.30 466 607 4.0E-12 T 28-03-2018 CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 Gene3D G3DSA:3.30.300.30 4834 4953 1.3E-36 T 28-03-2018 CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 Gene3D G3DSA:3.30.300.30 1583 1704 6.2E-36 T 28-03-2018 CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 Gene3D G3DSA:3.30.300.30 3763 3884 2.2E-35 T 28-03-2018 CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 Gene3D G3DSA:3.40.50.980 2423 2585 1.0E-35 T 28-03-2018 CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 Gene3D G3DSA:3.40.50.980 192 363 1.7E-31 T 28-03-2018 CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 Gene3D G3DSA:3.40.50.980 3512 3674 8.5E-33 T 28-03-2018 CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 Gene3D G3DSA:3.40.50.980 4581 4738 6.4E-34 T 28-03-2018 CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 Gene3D G3DSA:3.40.50.980 1331 1497 1.7E-32 T 28-03-2018 CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 5296 5414 5.1E-42 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1723 1738 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 Gene3D G3DSA:2.30.38.10 3676 3758 4.4E-24 T 28-03-2018 CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 Gene3D G3DSA:2.30.38.10 2592 2674 9.8E-19 T 28-03-2018 CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 Gene3D G3DSA:2.30.38.10 4747 4829 1.2E-24 T 28-03-2018 CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 Pfam PF00501 AMP-binding enzyme 2258 2684 8.2E-100 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 Pfam PF00501 AMP-binding enzyme 4437 4839 5.6E-100 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 Pfam PF00501 AMP-binding enzyme 3347 3768 2.8E-104 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 Pfam PF00501 AMP-binding enzyme 31 469 7.4E-70 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 Pfam PF00501 AMP-binding enzyme 1166 1588 1.5E-102 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 ProSitePatterns PS00012 Phosphopantetheine attachment site. 628 643 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 SUPERFAMILY SSF52777 1973 2219 2.11E-58 T 28-03-2018 CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 Pfam PF00550 Phosphopantetheine attachment site 2795 2859 1.2E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 Pfam PF00550 Phosphopantetheine attachment site 605 670 7.9E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 Pfam PF00550 Phosphopantetheine attachment site 3881 3944 6.2E-16 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 Pfam PF00550 Phosphopantetheine attachment site 1704 1764 3.3E-16 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 Pfam PF00550 Phosphopantetheine attachment site 4951 5015 8.6E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 SUPERFAMILY SSF52777 705 882 2.33E-46 T 28-03-2018 CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 Gene3D G3DSA:3.40.50.980 3337 3511 2.6E-51 T 28-03-2018 CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 Gene3D G3DSA:3.40.50.980 4427 4580 4.0E-45 T 28-03-2018 CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 Gene3D G3DSA:3.40.50.980 23 191 2.1E-26 T 28-03-2018 CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 Gene3D G3DSA:3.40.50.980 2250 2422 5.4E-44 T 28-03-2018 CIG75_RS02685 c163fad9dd987603537253758a5f7f65 5470 Gene3D G3DSA:3.40.50.980 1155 1330 3.8E-48 T 28-03-2018 CIG75_RS10875 240753c3a431cb1fabb05196e0a6612f 428 SUPERFAMILY SSF55205 3 426 1.96E-135 T 28-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CIG75_RS10875 240753c3a431cb1fabb05196e0a6612f 428 ProSitePatterns PS00885 EPSP synthase signature 2. 340 358 - T 28-03-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CIG75_RS10875 240753c3a431cb1fabb05196e0a6612f 428 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 13 427 1.0E-127 T 28-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CIG75_RS10875 240753c3a431cb1fabb05196e0a6612f 428 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 6 422 5.6E-130 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CIG75_RS10875 240753c3a431cb1fabb05196e0a6612f 428 ProSitePatterns PS00104 EPSP synthase signature 1. 88 102 - T 28-03-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CIG75_RS10875 240753c3a431cb1fabb05196e0a6612f 428 Gene3D G3DSA:3.65.10.10 220 428 1.2E-54 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CIG75_RS10875 240753c3a431cb1fabb05196e0a6612f 428 PIRSF PIRSF000505 1 428 9.9E-120 T 28-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CIG75_RS10875 240753c3a431cb1fabb05196e0a6612f 428 Gene3D G3DSA:3.65.10.10 20 219 2.3E-53 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CIG75_RS10875 240753c3a431cb1fabb05196e0a6612f 428 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 9 428 33.458 T 28-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CIG75_RS08580 508eceee41334ae3db3e1e7e19371dbf 440 Gene3D G3DSA:1.20.970.10 1 65 6.2E-23 T 28-03-2018 CIG75_RS08580 508eceee41334ae3db3e1e7e19371dbf 440 SUPERFAMILY SSF54680 329 431 1.96E-26 T 28-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CIG75_RS08580 508eceee41334ae3db3e1e7e19371dbf 440 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 343 415 4.0E-23 T 28-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CIG75_RS08580 508eceee41334ae3db3e1e7e19371dbf 440 TIGRFAM TIGR02644 Y_phosphoryl: pyrimidine-nucleoside phosphorylase 1 415 1.9E-171 T 28-03-2018 IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic GO:0006213|GO:0016154 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|Reactome: R-HSA-73614|Reactome: R-HSA-73621 CIG75_RS08580 508eceee41334ae3db3e1e7e19371dbf 440 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 108 123 - T 28-03-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CIG75_RS08580 508eceee41334ae3db3e1e7e19371dbf 440 Gene3D G3DSA:3.90.1170.30 336 422 1.0E-26 T 28-03-2018 CIG75_RS08580 508eceee41334ae3db3e1e7e19371dbf 440 SMART SM00941 343 417 5.2E-27 T 28-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CIG75_RS08580 508eceee41334ae3db3e1e7e19371dbf 440 SUPERFAMILY SSF52418 67 327 8.5E-92 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CIG75_RS08580 508eceee41334ae3db3e1e7e19371dbf 440 Pfam PF00591 Glycosyl transferase family, a/b domain 75 304 1.2E-41 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CIG75_RS08580 508eceee41334ae3db3e1e7e19371dbf 440 PIRSF PIRSF000478 1 432 1.5E-159 T 28-03-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CIG75_RS08580 508eceee41334ae3db3e1e7e19371dbf 440 SUPERFAMILY SSF47648 1 67 1.44E-20 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CIG75_RS08580 508eceee41334ae3db3e1e7e19371dbf 440 Pfam PF02885 Glycosyl transferase family, helical bundle domain 3 64 3.3E-21 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CIG75_RS08580 508eceee41334ae3db3e1e7e19371dbf 440 Gene3D G3DSA:3.40.1030.10 66 335 1.1E-89 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CIG75_RS16300 0db7bb9a6358592eb8519644a9a80959 410 SMART SM00287 347 409 8.9E-9 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type CIG75_RS16300 0db7bb9a6358592eb8519644a9a80959 410 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 74 220 2.1E-40 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CIG75_RS16300 0db7bb9a6358592eb8519644a9a80959 410 Pfam PF08239 Bacterial SH3 domain 357 406 5.4E-14 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type CIG75_RS16300 0db7bb9a6358592eb8519644a9a80959 410 Gene3D G3DSA:2.30.30.410 324 410 1.8E-15 T 28-03-2018 CIG75_RS16300 0db7bb9a6358592eb8519644a9a80959 410 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 75 221 6.9E-46 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CIG75_RS12395 223a302a9046dbb9e49bc08ef8263711 407 Gene3D G3DSA:3.40.50.620 1 244 3.7E-55 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CIG75_RS12395 223a302a9046dbb9e49bc08ef8263711 407 Hamap MF_01539 UPF0348 protein . 2 405 37.215 T 28-03-2018 IPR008513 Uncharacterised protein family UPF0348 CIG75_RS12395 223a302a9046dbb9e49bc08ef8263711 407 SUPERFAMILY SSF52374 1 107 2.82E-17 T 28-03-2018 CIG75_RS12395 223a302a9046dbb9e49bc08ef8263711 407 SUPERFAMILY SSF52374 160 232 2.82E-17 T 28-03-2018 CIG75_RS12395 223a302a9046dbb9e49bc08ef8263711 407 Pfam PF05636 HIGH Nucleotidyl Transferase 1 389 1.6E-133 T 28-03-2018 IPR008513 Uncharacterised protein family UPF0348 CIG75_RS19045 3e15b91d0390a9192fb32cc777305e77 295 Gene3D G3DSA:1.10.10.60 6 274 0.0017 T 28-03-2018 CIG75_RS19045 3e15b91d0390a9192fb32cc777305e77 295 Pfam PF10668 Phage terminase small subunit 1 60 3.4E-14 T 28-03-2018 IPR018925 Phage terminase small subunit CIG75_RS19780 d998682e715c2e7b938f82637e90c976 120 SUPERFAMILY SSF54736 49 120 6.63E-25 T 28-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CIG75_RS19780 d998682e715c2e7b938f82637e90c976 120 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 2 120 24.913 T 28-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS19780 d998682e715c2e7b938f82637e90c976 120 SUPERFAMILY SSF48300 1 56 2.49E-16 T 28-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS19780 d998682e715c2e7b938f82637e90c976 120 Gene3D G3DSA:3.30.1390.10 47 120 2.6E-31 T 28-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CIG75_RS19780 d998682e715c2e7b938f82637e90c976 120 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 3 47 1.0E-20 T 28-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS19780 d998682e715c2e7b938f82637e90c976 120 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 54 120 2.6E-31 T 28-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS19780 d998682e715c2e7b938f82637e90c976 120 Gene3D G3DSA:1.20.5.710 1 30 4.1E-17 T 28-03-2018 CIG75_RS19780 d998682e715c2e7b938f82637e90c976 120 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 55 120 1.0E-21 T 28-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS19780 d998682e715c2e7b938f82637e90c976 120 TIGRFAM TIGR00855 L12: ribosomal protein bL12 2 120 5.9E-50 T 28-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS05155 ab3c50f35f7061b39a76c8bdfbf4100f 204 TIGRFAM TIGR02894 DNA_bind_RsfA: transcription factor, RsfA family 8 185 2.2E-40 T 28-03-2018 IPR014243 Transcription factor, RsfA CIG75_RS05155 ab3c50f35f7061b39a76c8bdfbf4100f 204 SUPERFAMILY SSF46689 13 76 3.51E-5 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CIG75_RS05155 ab3c50f35f7061b39a76c8bdfbf4100f 204 Gene3D G3DSA:1.10.10.60 12 94 1.9E-6 T 28-03-2018 CIG75_RS05155 ab3c50f35f7061b39a76c8bdfbf4100f 204 Gene3D G3DSA:1.20.5.170 118 160 2.3E-4 T 28-03-2018 CIG75_RS02370 930b282ee379b280e4e72349bde914ac 79 SUPERFAMILY SSF117130 1 53 3.27E-20 T 28-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 CIG75_RS02370 930b282ee379b280e4e72349bde914ac 79 Pfam PF02599 Global regulator protein family 1 52 3.3E-27 T 28-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 CIG75_RS02370 930b282ee379b280e4e72349bde914ac 79 ProDom PD009007 STORAGE CARBON REGULATOR RNA-BINDING HOMOLOG CSRA REGULATOR GLOBAL PLASMID RSMA 1 48 3.0E-14 T 28-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 CIG75_RS02370 930b282ee379b280e4e72349bde914ac 79 Hamap MF_00167 Carbon storage regulator [csrA]. 1 69 21.374 T 28-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 CIG75_RS02370 930b282ee379b280e4e72349bde914ac 79 TIGRFAM TIGR00202 csrA: carbon storage regulator 1 62 2.3E-28 T 28-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 CIG75_RS09920 6be53fb71712c0a662c36a8fc47416f7 961 SMART SM00491 791 925 4.0E-28 T 28-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 CIG75_RS09920 6be53fb71712c0a662c36a8fc47416f7 961 SUPERFAMILY SSF53098 5 175 9.02E-54 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CIG75_RS09920 6be53fb71712c0a662c36a8fc47416f7 961 Gene3D G3DSA:3.40.50.300 722 936 1.3E-12 T 28-03-2018 CIG75_RS09920 6be53fb71712c0a662c36a8fc47416f7 961 SUPERFAMILY SSF52540 437 490 3.47E-27 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS09920 6be53fb71712c0a662c36a8fc47416f7 961 SUPERFAMILY SSF52540 884 920 3.47E-27 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS09920 6be53fb71712c0a662c36a8fc47416f7 961 SUPERFAMILY SSF52540 263 359 3.47E-27 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS09920 6be53fb71712c0a662c36a8fc47416f7 961 SMART SM00487 263 537 2.6E-13 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CIG75_RS09920 6be53fb71712c0a662c36a8fc47416f7 961 Pfam PF04851 Type III restriction enzyme, res subunit 266 486 3.2E-10 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CIG75_RS09920 6be53fb71712c0a662c36a8fc47416f7 961 Gene3D G3DSA:3.30.420.10 2 176 1.8E-44 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CIG75_RS09920 6be53fb71712c0a662c36a8fc47416f7 961 Pfam PF13307 Helicase C-terminal domain 774 937 5.5E-39 T 28-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 CIG75_RS09920 6be53fb71712c0a662c36a8fc47416f7 961 SMART SM00479 8 174 6.0E-50 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CIG75_RS09920 6be53fb71712c0a662c36a8fc47416f7 961 Gene3D G3DSA:3.40.50.300 266 721 1.9E-33 T 28-03-2018 CIG75_RS09920 6be53fb71712c0a662c36a8fc47416f7 961 TIGRFAM TIGR01407 dinG_rel: putative DnaQ family exonuclease/DinG family helicase 8 954 2.8E-214 T 28-03-2018 IPR006310 DnaQ exonuclease/DinG helicase, predicted CIG75_RS09920 6be53fb71712c0a662c36a8fc47416f7 961 Pfam PF00929 Exonuclease 10 165 3.2E-34 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CIG75_RS09920 6be53fb71712c0a662c36a8fc47416f7 961 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 5 174 1.4E-38 T 28-03-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CIG75_RS09920 6be53fb71712c0a662c36a8fc47416f7 961 SUPERFAMILY SSF52540 895 920 3.0E-8 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS09920 6be53fb71712c0a662c36a8fc47416f7 961 SUPERFAMILY SSF52540 768 864 3.0E-8 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS19875 cb74f2c35574bb84f61bbdf02ec6fb65 457 Pfam PF13541 Subunit ChlI of Mg-chelatase 343 429 2.3E-9 T 28-03-2018 CIG75_RS19875 cb74f2c35574bb84f61bbdf02ec6fb65 457 SUPERFAMILY SSF52540 71 291 1.08E-49 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS19875 cb74f2c35574bb84f61bbdf02ec6fb65 457 SMART SM00382 89 243 4.7E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS19875 cb74f2c35574bb84f61bbdf02ec6fb65 457 Gene3D G3DSA:3.30.230.10 282 456 2.9E-31 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CIG75_RS19875 cb74f2c35574bb84f61bbdf02ec6fb65 457 PRINTS PR01874 DNA repair protein radA signature 10 34 1.8E-93 T 28-03-2018 CIG75_RS19875 cb74f2c35574bb84f61bbdf02ec6fb65 457 PRINTS PR01874 DNA repair protein radA signature 173 197 1.8E-93 T 28-03-2018 CIG75_RS19875 cb74f2c35574bb84f61bbdf02ec6fb65 457 PRINTS PR01874 DNA repair protein radA signature 247 273 1.8E-93 T 28-03-2018 CIG75_RS19875 cb74f2c35574bb84f61bbdf02ec6fb65 457 PRINTS PR01874 DNA repair protein radA signature 123 140 1.8E-93 T 28-03-2018 CIG75_RS19875 cb74f2c35574bb84f61bbdf02ec6fb65 457 PRINTS PR01874 DNA repair protein radA signature 212 240 1.8E-93 T 28-03-2018 CIG75_RS19875 cb74f2c35574bb84f61bbdf02ec6fb65 457 PRINTS PR01874 DNA repair protein radA signature 321 344 1.8E-93 T 28-03-2018 CIG75_RS19875 cb74f2c35574bb84f61bbdf02ec6fb65 457 PRINTS PR01874 DNA repair protein radA signature 81 109 1.8E-93 T 28-03-2018 CIG75_RS19875 cb74f2c35574bb84f61bbdf02ec6fb65 457 SUPERFAMILY SSF54211 254 268 1.67E-43 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CIG75_RS19875 cb74f2c35574bb84f61bbdf02ec6fb65 457 SUPERFAMILY SSF54211 302 456 1.67E-43 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CIG75_RS19875 cb74f2c35574bb84f61bbdf02ec6fb65 457 Gene3D G3DSA:3.40.50.300 71 281 1.8E-45 T 28-03-2018 CIG75_RS19875 cb74f2c35574bb84f61bbdf02ec6fb65 457 Pfam PF13481 AAA domain 84 221 1.1E-15 T 28-03-2018 CIG75_RS19875 cb74f2c35574bb84f61bbdf02ec6fb65 457 Hamap MF_01498 DNA repair protein RadA [radA]. 21 455 44.493 T 28-03-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 CIG75_RS19875 cb74f2c35574bb84f61bbdf02ec6fb65 457 TIGRFAM TIGR00416 sms: DNA repair protein RadA 1 450 1.1E-202 T 28-03-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 CIG75_RS17090 99856b5ee27d0dbe3d0b6b142bf74fb6 450 ProSitePatterns PS00718 Sigma-54 factors family signature 2. 427 434 - T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CIG75_RS17090 99856b5ee27d0dbe3d0b6b142bf74fb6 450 Pfam PF04963 Sigma-54 factor, core binding domain 90 273 3.3E-53 T 28-03-2018 IPR007046 RNA polymerase sigma factor 54, core-binding GO:0003677|GO:0006352 CIG75_RS17090 99856b5ee27d0dbe3d0b6b142bf74fb6 450 Pfam PF00309 Sigma-54 factor, Activator interacting domain (AID) 9 53 2.5E-16 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CIG75_RS17090 99856b5ee27d0dbe3d0b6b142bf74fb6 450 Pfam PF04552 Sigma-54, DNA binding domain 289 447 3.4E-67 T 28-03-2018 IPR007634 RNA polymerase sigma factor 54, DNA-binding CIG75_RS17090 99856b5ee27d0dbe3d0b6b142bf74fb6 450 Gene3D G3DSA:1.10.10.10 294 386 3.4E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS17090 99856b5ee27d0dbe3d0b6b142bf74fb6 450 ProSitePatterns PS00717 Sigma-54 factors family signature 1. 336 355 - T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CIG75_RS17090 99856b5ee27d0dbe3d0b6b142bf74fb6 450 PIRSF PIRSF000774 3 449 1.3E-156 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CIG75_RS17090 99856b5ee27d0dbe3d0b6b142bf74fb6 450 PRINTS PR00045 Sigma-54 factor signature 364 375 4.2E-30 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CIG75_RS17090 99856b5ee27d0dbe3d0b6b142bf74fb6 450 PRINTS PR00045 Sigma-54 factor signature 422 440 4.2E-30 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CIG75_RS17090 99856b5ee27d0dbe3d0b6b142bf74fb6 450 PRINTS PR00045 Sigma-54 factor signature 159 176 4.2E-30 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CIG75_RS17090 99856b5ee27d0dbe3d0b6b142bf74fb6 450 PRINTS PR00045 Sigma-54 factor signature 348 360 4.2E-30 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CIG75_RS17090 99856b5ee27d0dbe3d0b6b142bf74fb6 450 TIGRFAM TIGR02395 rpoN_sigma: RNA polymerase sigma-54 factor 13 446 7.6E-138 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CIG75_RS11715 cd3aae23b247ef2e5b36f6c9ee6eabf7 291 Gene3D G3DSA:3.20.20.70 1 291 2.9E-96 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CIG75_RS11715 cd3aae23b247ef2e5b36f6c9ee6eabf7 291 PRINTS PR00146 Dihydrodipicolinate synthase signature 36 57 1.8E-32 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CIG75_RS11715 cd3aae23b247ef2e5b36f6c9ee6eabf7 291 PRINTS PR00146 Dihydrodipicolinate synthase signature 104 120 1.8E-32 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CIG75_RS11715 cd3aae23b247ef2e5b36f6c9ee6eabf7 291 PRINTS PR00146 Dihydrodipicolinate synthase signature 129 146 1.8E-32 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CIG75_RS11715 cd3aae23b247ef2e5b36f6c9ee6eabf7 291 PRINTS PR00146 Dihydrodipicolinate synthase signature 72 90 1.8E-32 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CIG75_RS11715 cd3aae23b247ef2e5b36f6c9ee6eabf7 291 SMART SM01130 2 290 8.1E-130 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CIG75_RS11715 cd3aae23b247ef2e5b36f6c9ee6eabf7 291 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 6 287 1.4E-105 T 28-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CIG75_RS11715 cd3aae23b247ef2e5b36f6c9ee6eabf7 291 PIRSF PIRSF001365 1 291 7.8E-91 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CIG75_RS11715 cd3aae23b247ef2e5b36f6c9ee6eabf7 291 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 2 288 61.607 T 28-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CIG75_RS11715 cd3aae23b247ef2e5b36f6c9ee6eabf7 291 SUPERFAMILY SSF51569 3 288 4.92E-97 T 28-03-2018 CIG75_RS11715 cd3aae23b247ef2e5b36f6c9ee6eabf7 291 Pfam PF00701 Dihydrodipicolinate synthetase family 3 287 3.1E-93 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CIG75_RS07855 67d26a76fe97d57e2e46fa78e3baf99f 203 SUPERFAMILY SSF52540 16 193 1.63E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS07855 67d26a76fe97d57e2e46fa78e3baf99f 203 Pfam PF01926 50S ribosome-binding GTPase 25 143 4.5E-21 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CIG75_RS07855 67d26a76fe97d57e2e46fa78e3baf99f 203 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 11 193 27.833 T 28-03-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 CIG75_RS07855 67d26a76fe97d57e2e46fa78e3baf99f 203 Gene3D G3DSA:3.40.50.300 2 198 4.9E-31 T 28-03-2018 CIG75_RS07855 67d26a76fe97d57e2e46fa78e3baf99f 203 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 6 189 9.2E-70 T 28-03-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 CIG75_RS09935 f28787d30c927bd57628834398c3728c 295 TIGRFAM TIGR02772 Ku_bact: Ku protein 2 252 9.1E-92 T 28-03-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type CIG75_RS09935 f28787d30c927bd57628834398c3728c 295 Pfam PF02735 Ku70/Ku80 beta-barrel domain 11 177 8.2E-39 T 28-03-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 CIG75_RS09935 f28787d30c927bd57628834398c3728c 295 SUPERFAMILY SSF100939 3 254 2.35E-52 T 28-03-2018 IPR016194 SPOC-like, C-terminal domain CIG75_RS09935 f28787d30c927bd57628834398c3728c 295 Gene3D G3DSA:2.40.290.10 1 172 2.4E-32 T 28-03-2018 IPR016194 SPOC-like, C-terminal domain CIG75_RS09935 f28787d30c927bd57628834398c3728c 295 SMART SM00559 52 180 9.0E-39 T 28-03-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 CIG75_RS09935 f28787d30c927bd57628834398c3728c 295 Gene3D G3DSA:1.10.1600.10 173 255 7.9E-4 T 28-03-2018 CIG75_RS09935 f28787d30c927bd57628834398c3728c 295 Hamap MF_01875 Non-homologous end joining protein Ku [ku]. 1 252 32.595 T 28-03-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type CIG75_RS09935 f28787d30c927bd57628834398c3728c 295 PIRSF PIRSF006493 1 293 1.7E-97 T 28-03-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type CIG75_RS13520 11acf38a5f82df533a44d6aa7e7bd009 743 Pfam PF03717 Penicillin-binding Protein dimerisation domain 53 226 4.1E-22 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CIG75_RS13520 11acf38a5f82df533a44d6aa7e7bd009 743 SUPERFAMILY SSF54184 686 740 6.41E-10 T 28-03-2018 CIG75_RS13520 11acf38a5f82df533a44d6aa7e7bd009 743 SUPERFAMILY SSF56601 245 591 1.24E-91 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CIG75_RS13520 11acf38a5f82df533a44d6aa7e7bd009 743 Pfam PF00905 Penicillin binding protein transpeptidase domain 271 582 4.3E-71 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CIG75_RS13520 11acf38a5f82df533a44d6aa7e7bd009 743 Gene3D G3DSA:3.90.1310.10 22 241 1.0E-38 T 28-03-2018 CIG75_RS13520 11acf38a5f82df533a44d6aa7e7bd009 743 SUPERFAMILY SSF56519 51 244 1.7E-32 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CIG75_RS13520 11acf38a5f82df533a44d6aa7e7bd009 743 Gene3D G3DSA:3.40.710.10 242 590 7.1E-85 T 28-03-2018 CIG75_RS13520 11acf38a5f82df533a44d6aa7e7bd009 743 Pfam PF03793 PASTA domain 686 740 9.4E-12 T 28-03-2018 IPR005543 PASTA domain CIG75_RS13520 11acf38a5f82df533a44d6aa7e7bd009 743 SMART SM00740 617 678 0.018 T 28-03-2018 IPR005543 PASTA domain CIG75_RS13520 11acf38a5f82df533a44d6aa7e7bd009 743 SMART SM00740 682 741 9.5E-7 T 28-03-2018 IPR005543 PASTA domain CIG75_RS13520 11acf38a5f82df533a44d6aa7e7bd009 743 SUPERFAMILY SSF54184 621 666 5.23E-7 T 28-03-2018 CIG75_RS20090 3864ce5fdf1182869169185243589315 72 Gene3D G3DSA:1.10.260.40 1 68 1.8E-19 T 28-03-2018 CIG75_RS20090 3864ce5fdf1182869169185243589315 72 SUPERFAMILY SSF47413 3 66 1.69E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CIG75_RS20090 3864ce5fdf1182869169185243589315 72 Pfam PF01381 Helix-turn-helix 9 63 2.4E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS20090 3864ce5fdf1182869169185243589315 72 SMART SM00530 8 63 1.3E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS17870 3684a867b5ec38664ae85bcf715c0b4b 392 SUPERFAMILY SSF103473 17 389 2.09E-47 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS17870 3684a867b5ec38664ae85bcf715c0b4b 392 Pfam PF12832 MFS_1 like family 18 367 2.9E-44 T 28-03-2018 IPR024989 Major facilitator superfamily associated domain CIG75_RS17870 3684a867b5ec38664ae85bcf715c0b4b 392 Gene3D G3DSA:1.20.1250.20 14 191 6.8E-22 T 28-03-2018 CIG75_RS17870 3684a867b5ec38664ae85bcf715c0b4b 392 Gene3D G3DSA:1.20.1250.20 196 392 6.6E-19 T 28-03-2018 CIG75_RS05670 34743899271300f8655f7c55c86682ed 209 Gene3D G3DSA:3.10.580.10 4 131 3.9E-13 T 28-03-2018 CIG75_RS05670 34743899271300f8655f7c55c86682ed 209 SUPERFAMILY SSF54631 3 121 1.95E-17 T 28-03-2018 CIG75_RS05670 34743899271300f8655f7c55c86682ed 209 Pfam PF00571 CBS domain 10 49 0.0038 T 28-03-2018 IPR000644 CBS domain CIG75_RS18665 421f6f19703703d61cb1be5788e916d6 472 PIRSF PIRSF000485 10 472 3.8E-178 T 28-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CIG75_RS18665 421f6f19703703d61cb1be5788e916d6 472 Gene3D G3DSA:3.60.20.10 155 238 1.3E-22 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CIG75_RS18665 421f6f19703703d61cb1be5788e916d6 472 Gene3D G3DSA:3.60.20.10 12 154 6.7E-34 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CIG75_RS18665 421f6f19703703d61cb1be5788e916d6 472 Gene3D G3DSA:3.40.50.2020 239 440 2.1E-31 T 28-03-2018 CIG75_RS18665 421f6f19703703d61cb1be5788e916d6 472 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 14 458 1.5E-161 T 28-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CIG75_RS18665 421f6f19703703d61cb1be5788e916d6 472 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 13 457 46.325 T 28-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CIG75_RS18665 421f6f19703703d61cb1be5788e916d6 472 Pfam PF13537 Glutamine amidotransferase domain 97 211 3.8E-20 T 28-03-2018 IPR017932 Glutamine amidotransferase type 2 domain CIG75_RS18665 421f6f19703703d61cb1be5788e916d6 472 SUPERFAMILY SSF53271 249 468 8.92E-72 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CIG75_RS18665 421f6f19703703d61cb1be5788e916d6 472 SUPERFAMILY SSF56235 14 255 5.23E-70 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CIG75_RS08425 873cbe78e053db0c1130b6f1c98d4201 449 Gene3D G3DSA:4.10.320.10 114 174 2.8E-19 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CIG75_RS08425 873cbe78e053db0c1130b6f1c98d4201 449 Gene3D G3DSA:3.90.1170.30 1 45 2.1E-14 T 28-03-2018 CIG75_RS08425 873cbe78e053db0c1130b6f1c98d4201 449 Gene3D G3DSA:3.30.559.10 203 445 1.6E-85 T 28-03-2018 CIG75_RS08425 873cbe78e053db0c1130b6f1c98d4201 449 Gene3D G3DSA:2.40.50.100 46 113 8.4E-7 T 28-03-2018 CIG75_RS08425 873cbe78e053db0c1130b6f1c98d4201 449 SUPERFAMILY SSF51230 3 91 4.83E-27 T 28-03-2018 IPR011053 Single hybrid motif CIG75_RS08425 873cbe78e053db0c1130b6f1c98d4201 449 SUPERFAMILY SSF47005 114 160 1.31E-11 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CIG75_RS08425 873cbe78e053db0c1130b6f1c98d4201 449 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 26 55 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CIG75_RS08425 873cbe78e053db0c1130b6f1c98d4201 449 Pfam PF02817 e3 binding domain 122 155 1.3E-12 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CIG75_RS08425 873cbe78e053db0c1130b6f1c98d4201 449 SUPERFAMILY SSF52777 219 443 1.87E-83 T 28-03-2018 CIG75_RS08425 873cbe78e053db0c1130b6f1c98d4201 449 Pfam PF00364 Biotin-requiring enzyme 3 75 1.2E-22 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CIG75_RS08425 873cbe78e053db0c1130b6f1c98d4201 449 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 219 443 1.4E-80 T 28-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CIG75_RS08810 4475bae591de992a2d7def5557a55b7d 169 Pfam PF09579 Sporulation protein YtfJ (Spore_YtfJ) 31 124 4.2E-29 T 28-03-2018 IPR014229 Sporulation protein YtfJ CIG75_RS08810 4475bae591de992a2d7def5557a55b7d 169 TIGRFAM TIGR02874 spore_ytfJ: sporulation protein YtfJ 3 134 3.1E-54 T 28-03-2018 IPR014229 Sporulation protein YtfJ CIG75_RS08810 4475bae591de992a2d7def5557a55b7d 169 PIRSF PIRSF021377 1 167 4.0E-57 T 28-03-2018 IPR014229 Sporulation protein YtfJ CIG75_RS18550 131362001e6468914b20920892660322 454 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 344 452 5.9E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS18550 131362001e6468914b20920892660322 454 SUPERFAMILY SSF158472 180 230 2.48E-14 T 28-03-2018 CIG75_RS18550 131362001e6468914b20920892660322 454 Pfam PF00672 HAMP domain 180 229 2.7E-16 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CIG75_RS18550 131362001e6468914b20920892660322 454 SUPERFAMILY SSF55874 288 453 1.15E-43 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS18550 131362001e6468914b20920892660322 454 SMART SM00387 343 454 1.8E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS18550 131362001e6468914b20920892660322 454 Gene3D G3DSA:3.30.565.10 306 454 1.2E-41 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS18550 131362001e6468914b20920892660322 454 SMART SM00304 180 232 6.9E-18 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CIG75_RS18550 131362001e6468914b20920892660322 454 SUPERFAMILY SSF47384 216 299 2.94E-21 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CIG75_RS18550 131362001e6468914b20920892660322 454 Gene3D G3DSA:1.10.287.130 223 294 5.0E-20 T 28-03-2018 CIG75_RS18550 131362001e6468914b20920892660322 454 Pfam PF00512 His Kinase A (phospho-acceptor) domain 233 298 5.8E-19 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CIG75_RS18550 131362001e6468914b20920892660322 454 PRINTS PR00344 Bacterial sensor protein C-terminal signature 380 394 1.3E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS18550 131362001e6468914b20920892660322 454 PRINTS PR00344 Bacterial sensor protein C-terminal signature 398 408 1.3E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS18550 131362001e6468914b20920892660322 454 PRINTS PR00344 Bacterial sensor protein C-terminal signature 415 433 1.3E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS18550 131362001e6468914b20920892660322 454 PRINTS PR00344 Bacterial sensor protein C-terminal signature 439 452 1.3E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS18550 131362001e6468914b20920892660322 454 SMART SM00388 233 299 2.8E-21 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CIG75_RS06290 080e3fea9367625068ed028e43a3073d 415 Pfam PF07690 Major Facilitator Superfamily 20 248 1.2E-33 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CIG75_RS06290 080e3fea9367625068ed028e43a3073d 415 ProSitePatterns PS00216 Sugar transport proteins signature 1. 69 85 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CIG75_RS06290 080e3fea9367625068ed028e43a3073d 415 Gene3D G3DSA:1.20.1250.20 10 204 3.1E-33 T 28-03-2018 CIG75_RS06290 080e3fea9367625068ed028e43a3073d 415 Gene3D G3DSA:1.20.1250.20 213 405 5.2E-22 T 28-03-2018 CIG75_RS06290 080e3fea9367625068ed028e43a3073d 415 SUPERFAMILY SSF103473 13 397 6.67E-64 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS02300 c66c5492b702fd6b33c77b49496f996e 446 Gene3D G3DSA:1.25.40.10 210 251 8.2E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS02300 c66c5492b702fd6b33c77b49496f996e 446 Gene3D G3DSA:1.10.150.200 151 209 7.3E-8 T 28-03-2018 CIG75_RS02300 c66c5492b702fd6b33c77b49496f996e 446 Gene3D G3DSA:1.25.40.10 71 150 0.0017 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS02300 c66c5492b702fd6b33c77b49496f996e 446 Pfam PF01381 Helix-turn-helix 16 69 1.6E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS02300 c66c5492b702fd6b33c77b49496f996e 446 Gene3D G3DSA:1.10.260.40 5 70 8.2E-16 T 28-03-2018 CIG75_RS02300 c66c5492b702fd6b33c77b49496f996e 446 SUPERFAMILY SSF47413 7 71 1.1E-14 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CIG75_RS02300 c66c5492b702fd6b33c77b49496f996e 446 Gene3D G3DSA:1.25.40.10 252 298 0.019 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS02300 c66c5492b702fd6b33c77b49496f996e 446 Pfam PF13424 Tetratricopeptide repeat 199 272 4.5E-8 T 28-03-2018 CIG75_RS02300 c66c5492b702fd6b33c77b49496f996e 446 SMART SM00530 15 69 1.5E-14 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS02300 c66c5492b702fd6b33c77b49496f996e 446 SMART SM00028 240 273 1.6 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS02300 c66c5492b702fd6b33c77b49496f996e 446 SMART SM00028 320 353 490.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS02300 c66c5492b702fd6b33c77b49496f996e 446 SMART SM00028 200 233 1.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS02300 c66c5492b702fd6b33c77b49496f996e 446 SUPERFAMILY SSF48452 158 348 4.77E-19 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS02300 c66c5492b702fd6b33c77b49496f996e 446 Gene3D G3DSA:1.25.40.10 299 443 3.7E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS02300 c66c5492b702fd6b33c77b49496f996e 446 SUPERFAMILY SSF48452 324 430 2.98E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS06530 e98167baee9e496722e4baf9ef3fc5ca 355 Gene3D G3DSA:3.40.50.2000 1 178 1.5E-40 T 28-03-2018 CIG75_RS06530 e98167baee9e496722e4baf9ef3fc5ca 355 Gene3D G3DSA:3.40.50.2000 179 340 2.4E-23 T 28-03-2018 CIG75_RS06530 e98167baee9e496722e4baf9ef3fc5ca 355 SUPERFAMILY SSF53756 2 354 1.02E-94 T 28-03-2018 CIG75_RS06530 e98167baee9e496722e4baf9ef3fc5ca 355 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 5 141 1.3E-42 T 28-03-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CIG75_RS06530 e98167baee9e496722e4baf9ef3fc5ca 355 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 4 353 28.899 T 28-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CIG75_RS06530 e98167baee9e496722e4baf9ef3fc5ca 355 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 1 346 2.2E-76 T 28-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CIG75_RS06530 e98167baee9e496722e4baf9ef3fc5ca 355 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 188 341 1.8E-26 T 28-03-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CIG75_RS00145 6f52de2bf7a406d1240302689dee6c3d 294 SUPERFAMILY SSF51366 18 268 1.74E-68 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CIG75_RS00145 6f52de2bf7a406d1240302689dee6c3d 294 TIGRFAM TIGR00343 TIGR00343: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 9 294 3.8E-156 T 28-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CIG75_RS00145 6f52de2bf7a406d1240302689dee6c3d 294 PIRSF PIRSF029271 1 294 2.4E-152 T 28-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CIG75_RS00145 6f52de2bf7a406d1240302689dee6c3d 294 Gene3D G3DSA:3.20.20.70 18 271 1.1E-69 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CIG75_RS00145 6f52de2bf7a406d1240302689dee6c3d 294 ProSitePatterns PS01235 PdxS/SNZ family signature. 205 223 - T 28-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CIG75_RS00145 6f52de2bf7a406d1240302689dee6c3d 294 Pfam PF01680 SOR/SNZ family 7 212 1.1E-106 T 28-03-2018 IPR033755 PdxS/SNZ N-terminal domain KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CIG75_RS00145 6f52de2bf7a406d1240302689dee6c3d 294 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 4 294 53.256 T 28-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CIG75_RS10145 36f3c1d71cb9b2f5cf9e197a8001a81c 241 Gene3D G3DSA:3.40.50.300 1 238 3.6E-59 T 28-03-2018 CIG75_RS10145 36f3c1d71cb9b2f5cf9e197a8001a81c 241 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS10145 36f3c1d71cb9b2f5cf9e197a8001a81c 241 SUPERFAMILY SSF52540 4 231 7.07E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS10145 36f3c1d71cb9b2f5cf9e197a8001a81c 241 SMART SM00382 29 211 8.4E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS10145 36f3c1d71cb9b2f5cf9e197a8001a81c 241 Pfam PF00005 ABC transporter 20 163 4.5E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS15510 55550ae2439201c31c5de2492831c075 330 Gene3D G3DSA:3.60.21.10 34 310 4.7E-31 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CIG75_RS15510 55550ae2439201c31c5de2492831c075 330 Pfam PF00149 Calcineurin-like phosphoesterase 37 239 2.2E-15 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CIG75_RS15510 55550ae2439201c31c5de2492831c075 330 SUPERFAMILY SSF56300 36 308 5.17E-35 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CIG75_RS14130 18059c1b6ea37f9bce1bbebc8cf80b1c 462 Pfam PF08353 Domain of unknown function (DUF1727) 326 438 5.4E-32 T 28-03-2018 IPR013564 Domain of unknown function DUF1727 CIG75_RS14130 18059c1b6ea37f9bce1bbebc8cf80b1c 462 Gene3D G3DSA:3.40.1190.10 51 311 6.3E-40 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CIG75_RS14130 18059c1b6ea37f9bce1bbebc8cf80b1c 462 Pfam PF08245 Mur ligase middle domain 57 285 1.6E-17 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CIG75_RS14130 18059c1b6ea37f9bce1bbebc8cf80b1c 462 SUPERFAMILY SSF53623 241 300 1.5E-32 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CIG75_RS14130 18059c1b6ea37f9bce1bbebc8cf80b1c 462 SUPERFAMILY SSF53623 53 194 1.5E-32 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CIG75_RS00935 cc375c3716790c395b14724922552db4 325 Gene3D G3DSA:3.40.50.1980 45 161 1.0E-20 T 28-03-2018 CIG75_RS00935 cc375c3716790c395b14724922552db4 325 Gene3D G3DSA:3.40.50.1980 162 325 3.6E-27 T 28-03-2018 CIG75_RS00935 cc375c3716790c395b14724922552db4 325 SUPERFAMILY SSF53807 50 318 4.32E-56 T 28-03-2018 CIG75_RS00935 cc375c3716790c395b14724922552db4 325 Pfam PF01497 Periplasmic binding protein 105 295 1.0E-29 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CIG75_RS00540 84751c67233f17baddda3fb0bb902acd 592 Gene3D G3DSA:3.30.450.20 30 168 1.7E-18 T 28-03-2018 CIG75_RS00540 84751c67233f17baddda3fb0bb902acd 592 Pfam PF00989 PAS fold 255 303 5.6E-7 T 28-03-2018 IPR013767 PAS fold GO:0006355 CIG75_RS00540 84751c67233f17baddda3fb0bb902acd 592 SMART SM00091 253 319 9.5E-6 T 28-03-2018 IPR000014 PAS domain CIG75_RS00540 84751c67233f17baddda3fb0bb902acd 592 SUPERFAMILY SSF158472 194 243 5.36E-11 T 28-03-2018 CIG75_RS00540 84751c67233f17baddda3fb0bb902acd 592 PRINTS PR00344 Bacterial sensor protein C-terminal signature 532 542 2.5E-19 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS00540 84751c67233f17baddda3fb0bb902acd 592 PRINTS PR00344 Bacterial sensor protein C-terminal signature 573 586 2.5E-19 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS00540 84751c67233f17baddda3fb0bb902acd 592 PRINTS PR00344 Bacterial sensor protein C-terminal signature 549 567 2.5E-19 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS00540 84751c67233f17baddda3fb0bb902acd 592 PRINTS PR00344 Bacterial sensor protein C-terminal signature 514 528 2.5E-19 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS00540 84751c67233f17baddda3fb0bb902acd 592 SUPERFAMILY SSF55785 241 356 2.44E-12 T 28-03-2018 IPR000014 PAS domain CIG75_RS00540 84751c67233f17baddda3fb0bb902acd 592 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 477 588 2.7E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS00540 84751c67233f17baddda3fb0bb902acd 592 SMART SM00388 364 431 1.8E-22 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CIG75_RS00540 84751c67233f17baddda3fb0bb902acd 592 SMART SM00304 194 246 2.9E-13 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CIG75_RS00540 84751c67233f17baddda3fb0bb902acd 592 Pfam PF00672 HAMP domain 194 243 4.4E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CIG75_RS00540 84751c67233f17baddda3fb0bb902acd 592 Gene3D G3DSA:3.30.450.20 250 369 3.6E-18 T 28-03-2018 CIG75_RS00540 84751c67233f17baddda3fb0bb902acd 592 Pfam PF00512 His Kinase A (phospho-acceptor) domain 364 430 1.2E-20 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CIG75_RS00540 84751c67233f17baddda3fb0bb902acd 592 Gene3D G3DSA:3.30.565.10 426 589 3.5E-46 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS00540 84751c67233f17baddda3fb0bb902acd 592 SUPERFAMILY SSF47384 349 431 8.44E-22 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CIG75_RS00540 84751c67233f17baddda3fb0bb902acd 592 Gene3D G3DSA:1.10.287.130 370 425 2.0E-20 T 28-03-2018 CIG75_RS00540 84751c67233f17baddda3fb0bb902acd 592 SMART SM00387 476 589 1.0E-43 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS00540 84751c67233f17baddda3fb0bb902acd 592 SUPERFAMILY SSF55874 420 587 4.45E-49 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS19210 08fe1119e80d66b3e10ec29fe2fa000f 299 Gene3D G3DSA:1.10.10.10 15 90 1.5E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS02825 312a7a013c22025a78ae546d4e20db6f 246 SUPERFAMILY SSF54001 148 236 3.92E-8 T 28-03-2018 CIG75_RS02825 312a7a013c22025a78ae546d4e20db6f 246 Gene3D G3DSA:2.30.30.410 28 116 4.6E-9 T 28-03-2018 CIG75_RS02825 312a7a013c22025a78ae546d4e20db6f 246 Pfam PF00877 NlpC/P60 family 148 234 3.0E-7 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CIG75_RS02825 312a7a013c22025a78ae546d4e20db6f 246 Gene3D G3DSA:3.90.1720.10 117 240 2.4E-10 T 28-03-2018 CIG75_RS00845 d1f15f3241bd6439eed1dd06671ade96 218 SUPERFAMILY SSF51569 2 213 1.05E-70 T 28-03-2018 CIG75_RS00845 d1f15f3241bd6439eed1dd06671ade96 218 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 3 212 2.0E-47 T 28-03-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 CIG75_RS00845 d1f15f3241bd6439eed1dd06671ade96 218 Gene3D G3DSA:3.20.20.70 1 217 3.3E-63 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CIG75_RS00845 d1f15f3241bd6439eed1dd06671ade96 218 TIGRFAM TIGR00875 fsa_talC_mipB: fructose-6-phosphate aldolase 2 212 4.7E-83 T 28-03-2018 IPR004731 Transaldolase type 3B/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 CIG75_RS01810 a2b0fdebd56789c3246dec507c2777aa 358 Gene3D G3DSA:1.20.58.410 2 94 2.2E-16 T 28-03-2018 CIG75_RS01810 a2b0fdebd56789c3246dec507c2777aa 358 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 1 355 1.8E-161 T 28-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 CIG75_RS01810 a2b0fdebd56789c3246dec507c2777aa 358 SUPERFAMILY SSF75620 8 351 8.37E-133 T 28-03-2018 CIG75_RS01810 a2b0fdebd56789c3246dec507c2777aa 358 SMART SM00937 63 177 5.7E-59 T 28-03-2018 IPR005139 Peptide chain release factor GO:0006415 CIG75_RS01810 a2b0fdebd56789c3246dec507c2777aa 358 Pfam PF00472 RF-1 domain 210 319 6.0E-41 T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CIG75_RS01810 a2b0fdebd56789c3246dec507c2777aa 358 Pfam PF03462 PCRF domain 8 202 9.1E-69 T 28-03-2018 IPR005139 Peptide chain release factor GO:0006415 CIG75_RS01810 a2b0fdebd56789c3246dec507c2777aa 358 Gene3D G3DSA:3.30.160.20 207 289 4.2E-31 T 28-03-2018 CIG75_RS01810 a2b0fdebd56789c3246dec507c2777aa 358 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 1 355 39.665 T 28-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 CIG75_RS18695 7bb5af4f4872c6a92cd7648ed25ba4d8 170 SUPERFAMILY SSF52255 4 168 1.28E-62 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CIG75_RS18695 7bb5af4f4872c6a92cd7648ed25ba4d8 170 PIRSF PIRSF001338 1 163 1.1E-64 T 28-03-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 CIG75_RS18695 7bb5af4f4872c6a92cd7648ed25ba4d8 170 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 5 156 31.331 T 28-03-2018 IPR033747 Class I PurE CIG75_RS18695 7bb5af4f4872c6a92cd7648ed25ba4d8 170 Gene3D G3DSA:3.40.50.7700 1 161 4.8E-64 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CIG75_RS18695 7bb5af4f4872c6a92cd7648ed25ba4d8 170 SMART SM01001 3 152 3.4E-86 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CIG75_RS18695 7bb5af4f4872c6a92cd7648ed25ba4d8 170 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 5 159 6.1E-60 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CIG75_RS18695 7bb5af4f4872c6a92cd7648ed25ba4d8 170 Pfam PF00731 AIR carboxylase 4 149 9.6E-61 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CIG75_RS08885 723fd1d7c7fc3900955da6f623906c88 214 SUPERFAMILY SSF51391 4 206 2.22E-67 T 28-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CIG75_RS08885 723fd1d7c7fc3900955da6f623906c88 214 Pfam PF02581 Thiamine monophosphate synthase 8 189 1.2E-63 T 28-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CIG75_RS08885 723fd1d7c7fc3900955da6f623906c88 214 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 7 201 1.1E-63 T 28-03-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CIG75_RS08885 723fd1d7c7fc3900955da6f623906c88 214 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 5 207 28.546 T 28-03-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CIG75_RS08885 723fd1d7c7fc3900955da6f623906c88 214 Gene3D G3DSA:3.20.20.70 2 207 4.3E-55 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CIG75_RS07205 41d7c61a98df0719d1dc503e15046fe6 463 SUPERFAMILY SSF48557 5 456 1.45E-133 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 CIG75_RS07205 41d7c61a98df0719d1dc503e15046fe6 463 Gene3D G3DSA:1.20.200.10 139 416 9.0E-71 T 28-03-2018 CIG75_RS07205 41d7c61a98df0719d1dc503e15046fe6 463 PRINTS PR00145 Argininosuccinate lyase family signature 318 334 2.3E-5 T 28-03-2018 CIG75_RS07205 41d7c61a98df0719d1dc503e15046fe6 463 PRINTS PR00145 Argininosuccinate lyase family signature 176 196 2.3E-5 T 28-03-2018 CIG75_RS07205 41d7c61a98df0719d1dc503e15046fe6 463 Pfam PF10415 Fumarase C C-terminus 409 461 8.5E-17 T 28-03-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CIG75_RS07205 41d7c61a98df0719d1dc503e15046fe6 463 Gene3D G3DSA:1.10.40.30 417 463 1.0E-16 T 28-03-2018 CIG75_RS07205 41d7c61a98df0719d1dc503e15046fe6 463 PRINTS PR00149 Fumarate lyase superfamily signature 181 199 8.5E-27 T 28-03-2018 IPR000362 Fumarate lyase family CIG75_RS07205 41d7c61a98df0719d1dc503e15046fe6 463 PRINTS PR00149 Fumarate lyase superfamily signature 272 299 8.5E-27 T 28-03-2018 IPR000362 Fumarate lyase family CIG75_RS07205 41d7c61a98df0719d1dc503e15046fe6 463 PRINTS PR00149 Fumarate lyase superfamily signature 135 153 8.5E-27 T 28-03-2018 IPR000362 Fumarate lyase family CIG75_RS07205 41d7c61a98df0719d1dc503e15046fe6 463 PRINTS PR00149 Fumarate lyase superfamily signature 318 334 8.5E-27 T 28-03-2018 IPR000362 Fumarate lyase family CIG75_RS07205 41d7c61a98df0719d1dc503e15046fe6 463 ProSitePatterns PS00163 Fumarate lyases signature. 318 327 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 CIG75_RS07205 41d7c61a98df0719d1dc503e15046fe6 463 Gene3D G3DSA:1.10.275.10 3 138 2.8E-54 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal CIG75_RS07205 41d7c61a98df0719d1dc503e15046fe6 463 Pfam PF00206 Lyase 13 343 2.4E-90 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal CIG75_RS13910 c5f7f5c906f71e1c4db2b67312cd8885 447 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 322 6.9E-85 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CIG75_RS13910 c5f7f5c906f71e1c4db2b67312cd8885 447 Gene3D G3DSA:3.30.470.20 210 444 1.8E-104 T 28-03-2018 CIG75_RS13910 c5f7f5c906f71e1c4db2b67312cd8885 447 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CIG75_RS13910 c5f7f5c906f71e1c4db2b67312cd8885 447 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CIG75_RS13910 c5f7f5c906f71e1c4db2b67312cd8885 447 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 443 1.5E-230 T 28-03-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 CIG75_RS13910 c5f7f5c906f71e1c4db2b67312cd8885 447 Gene3D G3DSA:3.30.1490.20 124 209 4.8E-23 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CIG75_RS13910 c5f7f5c906f71e1c4db2b67312cd8885 447 SUPERFAMILY SSF56059 83 348 1.94E-72 T 28-03-2018 CIG75_RS13910 c5f7f5c906f71e1c4db2b67312cd8885 447 Pfam PF02785 Biotin carboxylase C-terminal domain 336 442 1.2E-43 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CIG75_RS13910 c5f7f5c906f71e1c4db2b67312cd8885 447 SUPERFAMILY SSF51246 331 443 1.41E-46 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CIG75_RS13910 c5f7f5c906f71e1c4db2b67312cd8885 447 SMART SM00878 336 442 6.1E-68 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CIG75_RS13910 c5f7f5c906f71e1c4db2b67312cd8885 447 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 7.8E-46 T 28-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CIG75_RS13910 c5f7f5c906f71e1c4db2b67312cd8885 447 SUPERFAMILY SSF52440 1 113 3.6E-50 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CIG75_RS13910 c5f7f5c906f71e1c4db2b67312cd8885 447 Gene3D G3DSA:3.40.50.20 1 123 7.9E-54 T 28-03-2018 CIG75_RS15350 edd54f6ba808569e11ab4e69f68758c8 156 Gene3D G3DSA:3.40.30.10 1 155 2.6E-43 T 28-03-2018 CIG75_RS15350 edd54f6ba808569e11ab4e69f68758c8 156 Pfam PF00578 AhpC/TSA family 7 134 1.7E-40 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CIG75_RS15350 edd54f6ba808569e11ab4e69f68758c8 156 SUPERFAMILY SSF52833 5 155 1.19E-55 T 28-03-2018 IPR012336 Thioredoxin-like fold CIG75_RS15350 edd54f6ba808569e11ab4e69f68758c8 156 PIRSF PIRSF000239 1 156 3.6E-27 T 28-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CIG75_RS12970 e0d09f4583ec66bb57963635483148fe 153 Gene3D G3DSA:1.10.260.40 29 153 4.1E-19 T 28-03-2018 CIG75_RS12970 e0d09f4583ec66bb57963635483148fe 153 SUPERFAMILY SSF47413 32 94 1.56E-14 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CIG75_RS12970 e0d09f4583ec66bb57963635483148fe 153 Pfam PF01381 Helix-turn-helix 36 90 2.0E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS12970 e0d09f4583ec66bb57963635483148fe 153 SMART SM00530 35 90 6.5E-14 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS19905 91f08e99c0aa340deca9864e0e43b16d 191 Pfam PF08359 YsiA-like protein, C-terminal region 60 148 3.2E-7 T 28-03-2018 IPR013570 Transcription regulator YsiA, C-terminal CIG75_RS19905 91f08e99c0aa340deca9864e0e43b16d 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 8.4E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CIG75_RS19905 91f08e99c0aa340deca9864e0e43b16d 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 9 22 8.4E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CIG75_RS19905 91f08e99c0aa340deca9864e0e43b16d 191 SUPERFAMILY SSF46689 3 76 3.08E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CIG75_RS19905 91f08e99c0aa340deca9864e0e43b16d 191 SUPERFAMILY SSF48498 77 189 1.41E-22 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CIG75_RS19905 91f08e99c0aa340deca9864e0e43b16d 191 Gene3D G3DSA:1.10.10.60 2 55 3.0E-17 T 28-03-2018 CIG75_RS19905 91f08e99c0aa340deca9864e0e43b16d 191 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 53 4.3E-15 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CIG75_RS19905 91f08e99c0aa340deca9864e0e43b16d 191 Gene3D G3DSA:1.10.357.10 56 191 5.4E-22 T 28-03-2018 CIG75_RS01705 96d706ce57766b35172613531951be13 280 PIRSF PIRSF006250 4 280 2.2E-102 T 28-03-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 CIG75_RS01705 96d706ce57766b35172613531951be13 280 SUPERFAMILY SSF51690 111 277 7.85E-62 T 28-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CIG75_RS01705 96d706ce57766b35172613531951be13 280 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 20 109 1.6E-28 T 28-03-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 CIG75_RS01705 96d706ce57766b35172613531951be13 280 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 111 276 1.1E-66 T 28-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CIG75_RS01705 96d706ce57766b35172613531951be13 280 SUPERFAMILY SSF54675 6 110 1.72E-33 T 28-03-2018 CIG75_RS01705 96d706ce57766b35172613531951be13 280 Gene3D G3DSA:3.90.1170.20 1 136 1.4E-44 T 28-03-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 CIG75_RS01705 96d706ce57766b35172613531951be13 280 Gene3D G3DSA:3.20.20.70 137 267 8.9E-45 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CIG75_RS01705 96d706ce57766b35172613531951be13 280 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 12 277 2.8E-108 T 28-03-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 CIG75_RS07185 2c169f956922144c0a20c386fec48ab2 167 Gene3D G3DSA:3.40.630.30 6 167 5.0E-22 T 28-03-2018 CIG75_RS07185 2c169f956922144c0a20c386fec48ab2 167 SUPERFAMILY SSF55729 13 166 5.91E-25 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CIG75_RS07185 2c169f956922144c0a20c386fec48ab2 167 Pfam PF00583 Acetyltransferase (GNAT) family 56 142 3.4E-12 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CIG75_RS04555 8dd028b636798b1fa1dc4363546b58bb 231 Pfam PF09529 Integral membrane protein (intg_mem_TP0381) 1 214 2.5E-58 T 28-03-2018 IPR011737 Conserved hypothetical protein CHP02206, TP0381 CIG75_RS04555 8dd028b636798b1fa1dc4363546b58bb 231 TIGRFAM TIGR02206 intg_mem_TP0381: conserved hypothetical integral membrane protein TIGR02206 2 219 1.8E-63 T 28-03-2018 IPR011737 Conserved hypothetical protein CHP02206, TP0381 CIG75_RS20325 3b382dbf05220037f230d7aaebdc9220 883 Pfam PF08245 Mur ligase middle domain 484 701 1.5E-26 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CIG75_RS20325 3b382dbf05220037f230d7aaebdc9220 883 Pfam PF02655 ATP-grasp domain 211 443 9.1E-7 T 28-03-2018 IPR003806 ATP-grasp fold, DUF201-type GO:0005524|GO:0046872 CIG75_RS20325 3b382dbf05220037f230d7aaebdc9220 883 SUPERFAMILY SSF56059 384 469 5.05E-33 T 28-03-2018 CIG75_RS20325 3b382dbf05220037f230d7aaebdc9220 883 SUPERFAMILY SSF56059 214 320 5.05E-33 T 28-03-2018 CIG75_RS20325 3b382dbf05220037f230d7aaebdc9220 883 Gene3D G3DSA:3.90.190.20 731 863 9.3E-18 T 28-03-2018 CIG75_RS20325 3b382dbf05220037f230d7aaebdc9220 883 TIGRFAM TIGR02068 cya_phycin_syn: cyanophycin synthetase 2 865 0.0 T 28-03-2018 IPR011810 Cyanophycin synthetase GO:0005524|GO:0009059|GO:0016874 MetaCyc: PWY-7052 CIG75_RS20325 3b382dbf05220037f230d7aaebdc9220 883 SUPERFAMILY SSF53623 442 737 3.66E-45 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CIG75_RS20325 3b382dbf05220037f230d7aaebdc9220 883 Gene3D G3DSA:3.30.1490.20 163 282 2.0E-15 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CIG75_RS20325 3b382dbf05220037f230d7aaebdc9220 883 Gene3D G3DSA:3.30.470.20 283 488 9.2E-27 T 28-03-2018 CIG75_RS20325 3b382dbf05220037f230d7aaebdc9220 883 SUPERFAMILY SSF53244 725 852 9.16E-21 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CIG75_RS20325 3b382dbf05220037f230d7aaebdc9220 883 Pfam PF02875 Mur ligase family, glutamate ligase domain 725 797 1.4E-7 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CIG75_RS20325 3b382dbf05220037f230d7aaebdc9220 883 Gene3D G3DSA:3.40.1190.10 489 727 4.1E-44 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CIG75_RS12555 b10f50661ce1a081b1827ae73c50f8de 167 Gene3D G3DSA:3.90.20.10 9 62 9.6E-7 T 28-03-2018 CIG75_RS12555 b10f50661ce1a081b1827ae73c50f8de 167 SUPERFAMILY SSF57997 35 150 7.52E-5 T 28-03-2018 CIG75_RS12555 b10f50661ce1a081b1827ae73c50f8de 167 Gene3D G3DSA:3.90.20.10 63 166 4.6E-12 T 28-03-2018 CIG75_RS18595 f6309a54bdc356d4028dad1d0b458bc5 393 Gene3D G3DSA:1.10.260.40 4 76 4.1E-7 T 28-03-2018 CIG75_RS18595 f6309a54bdc356d4028dad1d0b458bc5 393 Gene3D G3DSA:3.30.70.100 77 168 2.3E-8 T 28-03-2018 CIG75_RS18595 f6309a54bdc356d4028dad1d0b458bc5 393 Gene3D G3DSA:1.25.40.10 180 383 4.1E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS18595 f6309a54bdc356d4028dad1d0b458bc5 393 SMART SM00028 204 237 78.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS18595 f6309a54bdc356d4028dad1d0b458bc5 393 SMART SM00028 244 277 66.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS18595 f6309a54bdc356d4028dad1d0b458bc5 393 SMART SM00028 122 155 0.019 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS18595 f6309a54bdc356d4028dad1d0b458bc5 393 SUPERFAMILY SSF48452 124 328 7.71E-17 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS18595 f6309a54bdc356d4028dad1d0b458bc5 393 SUPERFAMILY SSF47413 13 76 1.41E-5 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CIG75_RS17685 a670f0b597ecf3de033c3e7e639a1877 334 Pfam PF00586 AIR synthase related protein, N-terminal domain 32 145 1.6E-20 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CIG75_RS17685 a670f0b597ecf3de033c3e7e639a1877 334 Gene3D G3DSA:3.90.650.10 152 332 7.6E-43 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CIG75_RS17685 a670f0b597ecf3de033c3e7e639a1877 334 SUPERFAMILY SSF55326 2 146 2.44E-32 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CIG75_RS17685 a670f0b597ecf3de033c3e7e639a1877 334 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 6 329 31.65 T 28-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 CIG75_RS17685 a670f0b597ecf3de033c3e7e639a1877 334 Pfam PF02769 AIR synthase related protein, C-terminal domain 157 315 5.6E-13 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CIG75_RS17685 a670f0b597ecf3de033c3e7e639a1877 334 SUPERFAMILY SSF56042 150 321 1.48E-36 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CIG75_RS17685 a670f0b597ecf3de033c3e7e639a1877 334 PIRSF PIRSF005303 1 332 6.9E-96 T 28-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 CIG75_RS17685 a670f0b597ecf3de033c3e7e639a1877 334 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 7 332 2.5E-101 T 28-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 CIG75_RS17685 a670f0b597ecf3de033c3e7e639a1877 334 Gene3D G3DSA:3.30.1330.10 1 148 5.1E-30 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CIG75_RS11920 b42636e814c86aa07bc6196990362f30 262 Gene3D G3DSA:1.10.10.10 102 149 1.8E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS11920 b42636e814c86aa07bc6196990362f30 262 Pfam PF04542 Sigma-70 region 2 29 101 3.8E-16 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS11920 b42636e814c86aa07bc6196990362f30 262 TIGRFAM TIGR02479 FliA_WhiG: RNA polymerase sigma factor, FliA/WhiG family 29 253 1.5E-74 T 28-03-2018 IPR012845 RNA polymerase sigma factor, FliA/WhiG GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CIG75_RS11920 b42636e814c86aa07bc6196990362f30 262 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 56 69 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS11920 b42636e814c86aa07bc6196990362f30 262 Gene3D G3DSA:1.10.10.10 168 256 5.0E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS11920 b42636e814c86aa07bc6196990362f30 262 SUPERFAMILY SSF88946 8 101 2.22E-30 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS11920 b42636e814c86aa07bc6196990362f30 262 Gene3D G3DSA:1.10.601.10 3 100 6.1E-24 T 28-03-2018 CIG75_RS11920 b42636e814c86aa07bc6196990362f30 262 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 25 252 4.9E-35 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS11920 b42636e814c86aa07bc6196990362f30 262 SUPERFAMILY SSF88659 167 255 2.62E-21 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS11920 b42636e814c86aa07bc6196990362f30 262 PIRSF PIRSF000770 3 260 2.0E-41 T 28-03-2018 CIG75_RS11920 b42636e814c86aa07bc6196990362f30 262 Pfam PF04545 Sigma-70, region 4 203 250 1.1E-14 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS11920 b42636e814c86aa07bc6196990362f30 262 PRINTS PR00046 Major sigma-70 factor signature 206 218 1.6E-11 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS11920 b42636e814c86aa07bc6196990362f30 262 PRINTS PR00046 Major sigma-70 factor signature 238 249 1.6E-11 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS11920 b42636e814c86aa07bc6196990362f30 262 PRINTS PR00046 Major sigma-70 factor signature 56 69 1.6E-11 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS11920 b42636e814c86aa07bc6196990362f30 262 PRINTS PR00046 Major sigma-70 factor signature 80 88 1.6E-11 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS11920 b42636e814c86aa07bc6196990362f30 262 PRINTS PR00046 Major sigma-70 factor signature 223 238 1.6E-11 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS11920 b42636e814c86aa07bc6196990362f30 262 Pfam PF04539 Sigma-70 region 3 110 182 3.7E-7 T 28-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS11920 b42636e814c86aa07bc6196990362f30 262 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 223 249 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS11920 b42636e814c86aa07bc6196990362f30 262 SUPERFAMILY SSF88659 102 173 6.1E-13 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS12375 fb00a3e41a3a9a7c618ae2b86e045267 334 Hamap MF_00019 Phosphate acyltransferase [plsX]. 1 334 136.684 T 28-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 CIG75_RS12375 fb00a3e41a3a9a7c618ae2b86e045267 334 Pfam PF02504 Fatty acid synthesis protein 1 318 4.6E-104 T 28-03-2018 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 CIG75_RS12375 fb00a3e41a3a9a7c618ae2b86e045267 334 PIRSF PIRSF002465 1 333 4.9E-119 T 28-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 CIG75_RS12375 fb00a3e41a3a9a7c618ae2b86e045267 334 TIGRFAM TIGR00182 plsX: fatty acid/phospholipid synthesis protein PlsX 1 327 3.7E-113 T 28-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 CIG75_RS12375 fb00a3e41a3a9a7c618ae2b86e045267 334 Gene3D G3DSA:3.40.718.10 1 331 7.6E-105 T 28-03-2018 CIG75_RS12375 fb00a3e41a3a9a7c618ae2b86e045267 334 SUPERFAMILY SSF53659 2 327 4.11E-101 T 28-03-2018 CIG75_RS08925 31f2e0a5be7fb29f553f6e880748ceb7 305 ProDom PD128584 YPHB BH1976 TRANSMEMBRANE MEMBRANE SEAA 12 244 4.0E-52 T 28-03-2018 CIG75_RS08925 31f2e0a5be7fb29f553f6e880748ceb7 305 Pfam PF14045 YIEGIA protein 14 290 2.5E-100 T 28-03-2018 IPR025918 YIEGIA protein CIG75_RS16085 d11b79c6e5d778717cb0612fa1d8fdfd 211 Gene3D G3DSA:1.10.10.60 1 72 4.2E-18 T 28-03-2018 CIG75_RS16085 d11b79c6e5d778717cb0612fa1d8fdfd 211 SUPERFAMILY SSF48498 94 208 5.0E-8 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CIG75_RS16085 d11b79c6e5d778717cb0612fa1d8fdfd 211 SUPERFAMILY SSF46689 19 95 2.89E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CIG75_RS16085 d11b79c6e5d778717cb0612fa1d8fdfd 211 Gene3D G3DSA:1.10.357.10 73 211 7.5E-16 T 28-03-2018 CIG75_RS16085 d11b79c6e5d778717cb0612fa1d8fdfd 211 ProSitePatterns PS01081 TetR-type HTH domain signature. 37 68 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CIG75_RS16085 d11b79c6e5d778717cb0612fa1d8fdfd 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 1.4E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CIG75_RS16085 d11b79c6e5d778717cb0612fa1d8fdfd 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 1.4E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CIG75_RS16085 d11b79c6e5d778717cb0612fa1d8fdfd 211 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 68 4.4E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CIG75_RS10200 38a27613d4e9442cc321b30ea67c7253 298 ProSitePatterns PS01272 Glucokinase regulatory protein family signature. 186 203 - T 28-03-2018 IPR005486 Glucokinase regulatory protein, conserved site KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126|Reactome: R-HSA-170822|Reactome: R-HSA-5619107 CIG75_RS10200 38a27613d4e9442cc321b30ea67c7253 298 TIGRFAM TIGR00274 TIGR00274: N-acetylmuramic acid 6-phosphate etherase 7 297 3.3E-126 T 28-03-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126 CIG75_RS10200 38a27613d4e9442cc321b30ea67c7253 298 Gene3D G3DSA:1.10.8.10 241 267 0.0091 T 28-03-2018 CIG75_RS10200 38a27613d4e9442cc321b30ea67c7253 298 Gene3D G3DSA:1.10.8.10 268 297 1.0E-5 T 28-03-2018 CIG75_RS10200 38a27613d4e9442cc321b30ea67c7253 298 Gene3D G3DSA:3.40.50.10490 11 240 9.9E-53 T 28-03-2018 CIG75_RS10200 38a27613d4e9442cc321b30ea67c7253 298 Pfam PF13580 SIS domain 42 166 2.3E-11 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CIG75_RS10200 38a27613d4e9442cc321b30ea67c7253 298 Hamap MF_00068 N-acetylmuramic acid 6-phosphate etherase [murQ]. 3 296 42.805 T 28-03-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126 CIG75_RS10200 38a27613d4e9442cc321b30ea67c7253 298 SUPERFAMILY SSF53697 7 247 2.45E-70 T 28-03-2018 CIG75_RS03030 64e5799cf6e3ce2504dddfe60b70ff4f 140 Gene3D G3DSA:3.10.129.10 1 133 1.6E-31 T 28-03-2018 CIG75_RS03030 64e5799cf6e3ce2504dddfe60b70ff4f 140 Pfam PF13279 Thioesterase-like superfamily 8 122 6.7E-14 T 28-03-2018 CIG75_RS03030 64e5799cf6e3ce2504dddfe60b70ff4f 140 SUPERFAMILY SSF54637 2 128 9.23E-34 T 28-03-2018 IPR029069 HotDog domain CIG75_RS01670 fa2172b9d5e141ba7a61bf9f1ad5eb2e 477 Gene3D G3DSA:3.50.40.10 387 474 2.4E-7 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CIG75_RS01670 fa2172b9d5e141ba7a61bf9f1ad5eb2e 477 Pfam PF09179 TilS substrate binding domain 266 325 6.9E-6 T 28-03-2018 IPR015262 tRNA(Ile)-lysidine synthase , substrate-binding domain GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CIG75_RS01670 fa2172b9d5e141ba7a61bf9f1ad5eb2e 477 SUPERFAMILY SSF56037 385 469 2.12E-16 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CIG75_RS01670 fa2172b9d5e141ba7a61bf9f1ad5eb2e 477 Pfam PF11734 TilS substrate C-terminal domain 401 464 6.0E-12 T 28-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CIG75_RS01670 fa2172b9d5e141ba7a61bf9f1ad5eb2e 477 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 20 208 4.1E-60 T 28-03-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CIG75_RS01670 fa2172b9d5e141ba7a61bf9f1ad5eb2e 477 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 10 319 25.402 T 28-03-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CIG75_RS01670 fa2172b9d5e141ba7a61bf9f1ad5eb2e 477 SUPERFAMILY SSF82829 217 323 1.75E-15 T 28-03-2018 CIG75_RS01670 fa2172b9d5e141ba7a61bf9f1ad5eb2e 477 SMART SM00977 399 471 7.8E-20 T 28-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CIG75_RS01670 fa2172b9d5e141ba7a61bf9f1ad5eb2e 477 Pfam PF01171 PP-loop family 21 203 6.7E-59 T 28-03-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 CIG75_RS01670 fa2172b9d5e141ba7a61bf9f1ad5eb2e 477 Gene3D G3DSA:3.40.50.620 12 208 4.2E-48 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CIG75_RS01670 fa2172b9d5e141ba7a61bf9f1ad5eb2e 477 SUPERFAMILY SSF52402 11 239 2.65E-60 T 28-03-2018 CIG75_RS01670 fa2172b9d5e141ba7a61bf9f1ad5eb2e 477 TIGRFAM TIGR02433 lysidine_TilS_C: tRNA(Ile)-lysidine synthetase, C-terminal domain 399 443 1.6E-13 T 28-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CIG75_RS02595 db082d47926651c0d9ec0dd9f265e963 1351 Gene3D G3DSA:3.40.50.980 493 648 4.7E-47 T 28-03-2018 CIG75_RS02595 db082d47926651c0d9ec0dd9f265e963 1351 Gene3D G3DSA:1.10.1200.10 1023 1087 9.1E-18 T 28-03-2018 CIG75_RS02595 db082d47926651c0d9ec0dd9f265e963 1351 SUPERFAMILY SSF53474 1093 1344 7.19E-51 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS02595 db082d47926651c0d9ec0dd9f265e963 1351 Pfam PF00550 Phosphopantetheine attachment site 1020 1082 3.5E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS02595 db082d47926651c0d9ec0dd9f265e963 1351 Pfam PF00668 Condensation domain 35 479 8.7E-114 T 28-03-2018 IPR001242 Condensation domain CIG75_RS02595 db082d47926651c0d9ec0dd9f265e963 1351 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 522 930 1.6E-125 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS02595 db082d47926651c0d9ec0dd9f265e963 1351 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1041 1056 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS02595 db082d47926651c0d9ec0dd9f265e963 1351 SUPERFAMILY SSF52777 224 485 7.11E-63 T 28-03-2018 CIG75_RS02595 db082d47926651c0d9ec0dd9f265e963 1351 Gene3D G3DSA:2.30.38.10 816 896 3.6E-22 T 28-03-2018 CIG75_RS02595 db082d47926651c0d9ec0dd9f265e963 1351 PIRSF PIRSF001617 606 877 1.2E-19 T 28-03-2018 CIG75_RS02595 db082d47926651c0d9ec0dd9f265e963 1351 PIRSF PIRSF001617 949 1101 1.3E-19 T 28-03-2018 CIG75_RS02595 db082d47926651c0d9ec0dd9f265e963 1351 PIRSF PIRSF001617 871 957 5.6E-21 T 28-03-2018 CIG75_RS02595 db082d47926651c0d9ec0dd9f265e963 1351 PIRSF PIRSF001617 224 608 4.9E-29 T 28-03-2018 CIG75_RS02595 db082d47926651c0d9ec0dd9f265e963 1351 SMART SM00823 Phosphopantetheine attachment site 1017 1086 0.005 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS02595 db082d47926651c0d9ec0dd9f265e963 1351 SUPERFAMILY SSF47336 1011 1082 2.36E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS02595 db082d47926651c0d9ec0dd9f265e963 1351 Gene3D G3DSA:3.30.300.30 901 1022 1.5E-35 T 28-03-2018 CIG75_RS02595 db082d47926651c0d9ec0dd9f265e963 1351 Pfam PF00975 Thioesterase domain 1108 1340 5.0E-23 T 28-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CIG75_RS02595 db082d47926651c0d9ec0dd9f265e963 1351 Gene3D G3DSA:3.40.50.980 649 809 3.0E-34 T 28-03-2018 CIG75_RS02595 db082d47926651c0d9ec0dd9f265e963 1351 Pfam PF00501 AMP-binding enzyme 501 906 2.0E-91 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS02595 db082d47926651c0d9ec0dd9f265e963 1351 SUPERFAMILY SSF52777 39 216 2.45E-45 T 28-03-2018 CIG75_RS02595 db082d47926651c0d9ec0dd9f265e963 1351 SUPERFAMILY SSF56801 458 1030 6.02E-155 T 28-03-2018 CIG75_RS02595 db082d47926651c0d9ec0dd9f265e963 1351 Pfam PF13193 AMP-binding enzyme C-terminal domain 914 988 3.3E-15 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS02595 db082d47926651c0d9ec0dd9f265e963 1351 Gene3D G3DSA:3.40.50.1820 1092 1346 4.6E-25 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS02595 db082d47926651c0d9ec0dd9f265e963 1351 ProSitePatterns PS00455 Putative AMP-binding domain signature. 643 654 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS02595 db082d47926651c0d9ec0dd9f265e963 1351 Gene3D G3DSA:3.30.559.10 23 240 1.3E-38 T 28-03-2018 CIG75_RS16880 dfad646501bb82a6064795a2086055ce 502 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 255 440 1.2E-58 T 28-03-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 CIG75_RS16880 dfad646501bb82a6064795a2086055ce 502 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 4 229 6.3E-22 T 28-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain CIG75_RS16880 dfad646501bb82a6064795a2086055ce 502 SUPERFAMILY SSF52540 1 233 7.44E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS16880 dfad646501bb82a6064795a2086055ce 502 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 496 184.256 T 28-03-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 CIG75_RS16880 dfad646501bb82a6064795a2086055ce 502 Gene3D G3DSA:3.40.50.300 1 240 1.1E-49 T 28-03-2018 CIG75_RS16880 dfad646501bb82a6064795a2086055ce 502 TIGRFAM TIGR00313 cobQ: cobyric acid synthase CobQ 4 488 2.0E-169 T 28-03-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 CIG75_RS16880 dfad646501bb82a6064795a2086055ce 502 Gene3D G3DSA:3.40.50.880 242 487 4.4E-25 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CIG75_RS16880 dfad646501bb82a6064795a2086055ce 502 SUPERFAMILY SSF52317 256 449 1.74E-37 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CIG75_RS09910 b59f31185bb8d3f731313e8f6ed68c03 536 Pfam PF13432 Tetratricopeptide repeat 330 383 4.9E-7 T 28-03-2018 CIG75_RS09910 b59f31185bb8d3f731313e8f6ed68c03 536 SUPERFAMILY SSF48452 223 456 1.8E-33 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS09910 b59f31185bb8d3f731313e8f6ed68c03 536 Gene3D G3DSA:1.25.40.10 462 535 1.6E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS09910 b59f31185bb8d3f731313e8f6ed68c03 536 Gene3D G3DSA:1.25.40.10 241 285 3.9E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS09910 b59f31185bb8d3f731313e8f6ed68c03 536 Gene3D G3DSA:1.10.287.1110 342 354 0.011 T 28-03-2018 CIG75_RS09910 b59f31185bb8d3f731313e8f6ed68c03 536 Gene3D G3DSA:1.25.40.10 148 240 2.1E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS09910 b59f31185bb8d3f731313e8f6ed68c03 536 SUPERFAMILY SSF48452 156 254 7.59E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS09910 b59f31185bb8d3f731313e8f6ed68c03 536 SMART SM00028 496 529 140.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS09910 b59f31185bb8d3f731313e8f6ed68c03 536 SMART SM00028 151 184 54.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS09910 b59f31185bb8d3f731313e8f6ed68c03 536 SMART SM00028 256 289 7.5E-5 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS09910 b59f31185bb8d3f731313e8f6ed68c03 536 SMART SM00028 358 391 0.006 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS09910 b59f31185bb8d3f731313e8f6ed68c03 536 SMART SM00028 222 255 0.82 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS09910 b59f31185bb8d3f731313e8f6ed68c03 536 SMART SM00028 392 425 31.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS09910 b59f31185bb8d3f731313e8f6ed68c03 536 SMART SM00028 426 459 28.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS09910 b59f31185bb8d3f731313e8f6ed68c03 536 SMART SM00028 324 357 9.6 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS09910 b59f31185bb8d3f731313e8f6ed68c03 536 SMART SM00028 185 218 220.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS09910 b59f31185bb8d3f731313e8f6ed68c03 536 SMART SM00028 290 323 15.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS09910 b59f31185bb8d3f731313e8f6ed68c03 536 SMART SM00028 462 495 150.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS09910 b59f31185bb8d3f731313e8f6ed68c03 536 SUPERFAMILY SSF48452 424 524 6.03E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS09910 b59f31185bb8d3f731313e8f6ed68c03 536 Pfam PF00515 Tetratricopeptide repeat 260 289 3.6E-7 T 28-03-2018 IPR001440 Tetratricopeptide repeat 1 GO:0005515 CIG75_RS09910 b59f31185bb8d3f731313e8f6ed68c03 536 Gene3D G3DSA:1.25.40.10 286 341 5.1E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS09910 b59f31185bb8d3f731313e8f6ed68c03 536 Gene3D G3DSA:1.25.40.10 355 381 7.3E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS09910 b59f31185bb8d3f731313e8f6ed68c03 536 Gene3D G3DSA:1.25.40.10 382 461 1.0E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS10635 3de8a14f5d604eb38ee8c7c5fe877bd0 976 Gene3D G3DSA:3.40.47.10 1 269 1.6E-69 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS10635 3de8a14f5d604eb38ee8c7c5fe877bd0 976 ProSitePatterns PS00012 Phosphopantetheine attachment site. 924 939 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS10635 3de8a14f5d604eb38ee8c7c5fe877bd0 976 SUPERFAMILY SSF52151 531 652 1.05E-26 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CIG75_RS10635 3de8a14f5d604eb38ee8c7c5fe877bd0 976 SUPERFAMILY SSF52151 718 809 1.05E-26 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CIG75_RS10635 3de8a14f5d604eb38ee8c7c5fe877bd0 976 SUPERFAMILY SSF47336 897 965 3.27E-16 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10635 3de8a14f5d604eb38ee8c7c5fe877bd0 976 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 170 186 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CIG75_RS10635 3de8a14f5d604eb38ee8c7c5fe877bd0 976 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 533 828 5.0E-16 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CIG75_RS10635 3de8a14f5d604eb38ee8c7c5fe877bd0 976 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 265 384 2.2E-40 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CIG75_RS10635 3de8a14f5d604eb38ee8c7c5fe877bd0 976 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 386 495 1.7E-20 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS10635 3de8a14f5d604eb38ee8c7c5fe877bd0 976 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 8 257 3.2E-70 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CIG75_RS10635 3de8a14f5d604eb38ee8c7c5fe877bd0 976 Pfam PF00698 Acyl transferase domain 533 790 1.3E-19 T 28-03-2018 IPR014043 Acyl transferase CIG75_RS10635 3de8a14f5d604eb38ee8c7c5fe877bd0 976 Gene3D G3DSA:3.40.47.10 273 434 6.9E-56 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS10635 3de8a14f5d604eb38ee8c7c5fe877bd0 976 SUPERFAMILY SSF53901 411 432 2.34E-85 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS10635 3de8a14f5d604eb38ee8c7c5fe877bd0 976 SUPERFAMILY SSF53901 5 123 2.34E-85 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS10635 3de8a14f5d604eb38ee8c7c5fe877bd0 976 SUPERFAMILY SSF53901 153 379 2.34E-85 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS10635 3de8a14f5d604eb38ee8c7c5fe877bd0 976 Gene3D G3DSA:1.10.1200.10 894 972 1.2E-17 T 28-03-2018 CIG75_RS10635 3de8a14f5d604eb38ee8c7c5fe877bd0 976 Gene3D G3DSA:3.40.366.10 523 714 1.9E-28 T 28-03-2018 CIG75_RS10635 3de8a14f5d604eb38ee8c7c5fe877bd0 976 Gene3D G3DSA:3.40.366.10 715 824 6.5E-8 T 28-03-2018 CIG75_RS10635 3de8a14f5d604eb38ee8c7c5fe877bd0 976 Pfam PF00550 Phosphopantetheine attachment site 903 963 1.5E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10635 3de8a14f5d604eb38ee8c7c5fe877bd0 976 SMART SM00825 Beta-ketoacyl synthase 9 436 1.0E-186 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CIG75_RS07030 fce8066b3f5e11a4421126e481514437 226 Pfam PF00877 NlpC/P60 family 121 222 1.0E-29 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CIG75_RS07030 fce8066b3f5e11a4421126e481514437 226 SUPERFAMILY SSF54001 107 224 2.16E-39 T 28-03-2018 CIG75_RS07030 fce8066b3f5e11a4421126e481514437 226 Pfam PF01471 Putative peptidoglycan binding domain 42 94 4.3E-12 T 28-03-2018 IPR002477 Peptidoglycan binding-like CIG75_RS07030 fce8066b3f5e11a4421126e481514437 226 SUPERFAMILY SSF47090 31 94 1.88E-14 T 28-03-2018 IPR002477 Peptidoglycan binding-like CIG75_RS07030 fce8066b3f5e11a4421126e481514437 226 Gene3D G3DSA:3.90.1720.10 99 226 1.3E-36 T 28-03-2018 CIG75_RS07030 fce8066b3f5e11a4421126e481514437 226 Gene3D G3DSA:1.10.101.10 28 98 1.3E-14 T 28-03-2018 IPR002477 Peptidoglycan binding-like CIG75_RS06670 2ca17dc967f8559b83f4e043cd2b9c19 452 SMART SM01260 58 450 1.4E-58 T 28-03-2018 IPR007822 Lanthionine synthetase C-like CIG75_RS06670 2ca17dc967f8559b83f4e043cd2b9c19 452 SUPERFAMILY SSF158745 57 452 1.29E-73 T 28-03-2018 CIG75_RS06670 2ca17dc967f8559b83f4e043cd2b9c19 452 PRINTS PR01950 LanC-like protein superfamily signature 420 437 2.4E-22 T 28-03-2018 IPR007822 Lanthionine synthetase C-like CIG75_RS06670 2ca17dc967f8559b83f4e043cd2b9c19 452 PRINTS PR01950 LanC-like protein superfamily signature 312 332 2.4E-22 T 28-03-2018 IPR007822 Lanthionine synthetase C-like CIG75_RS06670 2ca17dc967f8559b83f4e043cd2b9c19 452 PRINTS PR01950 LanC-like protein superfamily signature 168 183 2.4E-22 T 28-03-2018 IPR007822 Lanthionine synthetase C-like CIG75_RS06670 2ca17dc967f8559b83f4e043cd2b9c19 452 PRINTS PR01950 LanC-like protein superfamily signature 240 256 2.4E-22 T 28-03-2018 IPR007822 Lanthionine synthetase C-like CIG75_RS06670 2ca17dc967f8559b83f4e043cd2b9c19 452 PRINTS PR01950 LanC-like protein superfamily signature 61 79 2.4E-22 T 28-03-2018 IPR007822 Lanthionine synthetase C-like CIG75_RS06670 2ca17dc967f8559b83f4e043cd2b9c19 452 PRINTS PR01950 LanC-like protein superfamily signature 362 375 2.4E-22 T 28-03-2018 IPR007822 Lanthionine synthetase C-like CIG75_RS06670 2ca17dc967f8559b83f4e043cd2b9c19 452 PRINTS PR01955 Frankia sp. LanC-like protein signature 261 281 8.4E-46 T 28-03-2018 CIG75_RS06670 2ca17dc967f8559b83f4e043cd2b9c19 452 PRINTS PR01955 Frankia sp. LanC-like protein signature 361 381 8.4E-46 T 28-03-2018 CIG75_RS06670 2ca17dc967f8559b83f4e043cd2b9c19 452 PRINTS PR01955 Frankia sp. LanC-like protein signature 62 77 8.4E-46 T 28-03-2018 CIG75_RS06670 2ca17dc967f8559b83f4e043cd2b9c19 452 PRINTS PR01955 Frankia sp. LanC-like protein signature 237 261 8.4E-46 T 28-03-2018 CIG75_RS06670 2ca17dc967f8559b83f4e043cd2b9c19 452 PRINTS PR01955 Frankia sp. LanC-like protein signature 312 335 8.4E-46 T 28-03-2018 CIG75_RS06670 2ca17dc967f8559b83f4e043cd2b9c19 452 PRINTS PR01955 Frankia sp. LanC-like protein signature 421 438 8.4E-46 T 28-03-2018 CIG75_RS06670 2ca17dc967f8559b83f4e043cd2b9c19 452 PRINTS PR01955 Frankia sp. LanC-like protein signature 167 183 8.4E-46 T 28-03-2018 CIG75_RS06670 2ca17dc967f8559b83f4e043cd2b9c19 452 PRINTS PR01955 Frankia sp. LanC-like protein signature 289 303 8.4E-46 T 28-03-2018 CIG75_RS06670 2ca17dc967f8559b83f4e043cd2b9c19 452 Pfam PF05147 Lanthionine synthetase C-like protein 61 450 5.5E-63 T 28-03-2018 IPR007822 Lanthionine synthetase C-like CIG75_RS06670 2ca17dc967f8559b83f4e043cd2b9c19 452 Gene3D G3DSA:1.50.10.20 29 357 6.2E-4 T 28-03-2018 CIG75_RS02450 cb5396a13ae7fe141800875323944a31 230 Gene3D G3DSA:3.90.550.10 3 229 1.6E-39 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CIG75_RS02450 cb5396a13ae7fe141800875323944a31 230 SUPERFAMILY SSF53448 6 226 8.08E-62 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CIG75_RS02450 cb5396a13ae7fe141800875323944a31 230 Pfam PF02348 Cytidylyltransferase 9 138 1.7E-20 T 28-03-2018 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 CIG75_RS02025 4e664739a6e4101efda6ec319c9e4f21 332 SUPERFAMILY SSF54106 260 304 1.44E-9 T 28-03-2018 IPR018392 LysM domain CIG75_RS02025 4e664739a6e4101efda6ec319c9e4f21 332 Pfam PF01476 LysM domain 263 304 5.5E-12 T 28-03-2018 IPR018392 LysM domain CIG75_RS02025 4e664739a6e4101efda6ec319c9e4f21 332 Pfam PF01476 LysM domain 214 256 5.2E-13 T 28-03-2018 IPR018392 LysM domain CIG75_RS02025 4e664739a6e4101efda6ec319c9e4f21 332 SUPERFAMILY SSF54106 212 256 1.7E-9 T 28-03-2018 IPR018392 LysM domain CIG75_RS02025 4e664739a6e4101efda6ec319c9e4f21 332 Pfam PF07833 Copper amine oxidase N-terminal domain 116 206 1.5E-25 T 28-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CIG75_RS02025 4e664739a6e4101efda6ec319c9e4f21 332 SUPERFAMILY SSF55383 117 199 2.62E-23 T 28-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CIG75_RS02025 4e664739a6e4101efda6ec319c9e4f21 332 Gene3D G3DSA:3.10.350.10 259 306 2.2E-14 T 28-03-2018 CIG75_RS02025 4e664739a6e4101efda6ec319c9e4f21 332 Gene3D G3DSA:3.30.457.10 118 196 3.5E-25 T 28-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CIG75_RS02025 4e664739a6e4101efda6ec319c9e4f21 332 SMART SM00257 261 304 2.8E-13 T 28-03-2018 IPR018392 LysM domain CIG75_RS02025 4e664739a6e4101efda6ec319c9e4f21 332 SMART SM00257 213 256 2.9E-12 T 28-03-2018 IPR018392 LysM domain CIG75_RS02025 4e664739a6e4101efda6ec319c9e4f21 332 Gene3D G3DSA:3.10.350.10 211 257 2.8E-13 T 28-03-2018 CIG75_RS10920 4108ae94d2e5b896c7192d9f0dff96f9 385 Gene3D G3DSA:3.60.150.10 1 385 1.3E-140 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CIG75_RS10920 4108ae94d2e5b896c7192d9f0dff96f9 385 ProSitePatterns PS00787 Chorismate synthase signature 1. 8 23 - T 28-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CIG75_RS10920 4108ae94d2e5b896c7192d9f0dff96f9 385 TIGRFAM TIGR00033 aroC: chorismate synthase 2 365 2.0E-126 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CIG75_RS10920 4108ae94d2e5b896c7192d9f0dff96f9 385 Hamap MF_00300 Chorismate synthase [aroC]. 2 367 36.311 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CIG75_RS10920 4108ae94d2e5b896c7192d9f0dff96f9 385 ProSitePatterns PS00789 Chorismate synthase signature 3. 334 350 - T 28-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CIG75_RS10920 4108ae94d2e5b896c7192d9f0dff96f9 385 SUPERFAMILY SSF103263 1 381 6.93E-142 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CIG75_RS10920 4108ae94d2e5b896c7192d9f0dff96f9 385 PIRSF PIRSF001456 1 377 1.2E-127 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CIG75_RS10920 4108ae94d2e5b896c7192d9f0dff96f9 385 Pfam PF01264 Chorismate synthase 2 360 3.0E-122 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CIG75_RS02245 532d154fd87e04eedf3184740b16d954 296 TIGRFAM TIGR02136 ptsS_2: phosphate binding protein 12 291 2.2E-66 T 28-03-2018 IPR011862 Phosphate binding protein GO:0006810 CIG75_RS02245 532d154fd87e04eedf3184740b16d954 296 Gene3D G3DSA:3.40.190.10 48 173 6.3E-30 T 28-03-2018 CIG75_RS02245 532d154fd87e04eedf3184740b16d954 296 SUPERFAMILY SSF53850 52 292 6.4E-66 T 28-03-2018 CIG75_RS02245 532d154fd87e04eedf3184740b16d954 296 Gene3D G3DSA:3.40.190.10 174 295 4.5E-15 T 28-03-2018 CIG75_RS02245 532d154fd87e04eedf3184740b16d954 296 Pfam PF12849 PBP superfamily domain 47 275 3.4E-33 T 28-03-2018 IPR024370 PBP domain CIG75_RS10235 f104eccab35cca43d91d1ee1fe51df58 388 Pfam PF00144 Beta-lactamase 10 371 3.4E-57 T 28-03-2018 IPR001466 Beta-lactamase-related CIG75_RS10235 f104eccab35cca43d91d1ee1fe51df58 388 Gene3D G3DSA:3.40.710.10 1 384 4.4E-75 T 28-03-2018 CIG75_RS10235 f104eccab35cca43d91d1ee1fe51df58 388 SUPERFAMILY SSF56601 252 378 1.71E-69 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CIG75_RS10235 f104eccab35cca43d91d1ee1fe51df58 388 SUPERFAMILY SSF56601 5 199 1.71E-69 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CIG75_RS11825 4f3a78de6d9588d22000da529df79aed 1453 Gene3D G3DSA:3.20.20.140 342 774 5.6E-59 T 28-03-2018 CIG75_RS11825 4f3a78de6d9588d22000da529df79aed 1453 SUPERFAMILY SSF50249 244 329 5.6E-8 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CIG75_RS11825 4f3a78de6d9588d22000da529df79aed 1453 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 834 1258 3.3E-96 T 28-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CIG75_RS11825 4f3a78de6d9588d22000da529df79aed 1453 Pfam PF01336 OB-fold nucleic acid binding domain 248 313 1.4E-6 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CIG75_RS11825 4f3a78de6d9588d22000da529df79aed 1453 Pfam PF14579 Helix-hairpin-helix motif 1364 1444 8.6E-8 T 28-03-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CIG75_RS11825 4f3a78de6d9588d22000da529df79aed 1453 SMART SM00479 432 598 3.9E-53 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CIG75_RS11825 4f3a78de6d9588d22000da529df79aed 1453 Pfam PF02811 PHP domain 344 705 1.2E-49 T 28-03-2018 IPR004013 PHP domain GO:0003824 CIG75_RS11825 4f3a78de6d9588d22000da529df79aed 1453 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 432 647 1.2E-35 T 28-03-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CIG75_RS11825 4f3a78de6d9588d22000da529df79aed 1453 SMART SM00481 343 410 1.4E-24 T 28-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal CIG75_RS11825 4f3a78de6d9588d22000da529df79aed 1453 Hamap MF_00356 DNA polymerase III PolC-type [polC]. 1 1453 383.795 T 28-03-2018 IPR006308 DNA polymerase III, alpha subunit, Gram-positive type GO:0003677|GO:0003887|GO:0005737|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CIG75_RS11825 4f3a78de6d9588d22000da529df79aed 1453 Pfam PF00929 Exonuclease 434 589 7.7E-38 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CIG75_RS11825 4f3a78de6d9588d22000da529df79aed 1453 SUPERFAMILY SSF53098 432 884 6.83E-96 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CIG75_RS11825 4f3a78de6d9588d22000da529df79aed 1453 TIGRFAM TIGR01405 polC_Gram_pos: DNA polymerase III, alpha subunit, Gram-positive type 240 1453 0.0 T 28-03-2018 IPR006308 DNA polymerase III, alpha subunit, Gram-positive type GO:0003677|GO:0003887|GO:0005737|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CIG75_RS11825 4f3a78de6d9588d22000da529df79aed 1453 Gene3D G3DSA:2.40.50.140 230 328 9.0E-21 T 28-03-2018 CIG75_RS18120 75743f837a554122ac07b25a6521e498 259 Gene3D G3DSA:1.10.12.10 208 259 1.3E-18 T 28-03-2018 IPR014748 Crontonase, C-terminal CIG75_RS18120 75743f837a554122ac07b25a6521e498 259 Gene3D G3DSA:3.90.226.10 1 207 3.4E-71 T 28-03-2018 CIG75_RS18120 75743f837a554122ac07b25a6521e498 259 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 258 2.6E-71 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CIG75_RS18120 75743f837a554122ac07b25a6521e498 259 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 100 120 - T 28-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CIG75_RS18120 75743f837a554122ac07b25a6521e498 259 SUPERFAMILY SSF52096 1 259 4.21E-92 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CIG75_RS02870 9688938fdd82d6e5a64006879e75de5e 260 SUPERFAMILY SSF51621 1 254 9.42E-73 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CIG75_RS02870 9688938fdd82d6e5a64006879e75de5e 260 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 24 211 2.5E-32 T 28-03-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 CIG75_RS02870 9688938fdd82d6e5a64006879e75de5e 260 Gene3D G3DSA:3.20.20.60 1 255 2.5E-42 T 28-03-2018 CIG75_RS09305 7acb2be25f766317444b158e25de758a 424 Gene3D G3DSA:3.40.50.10860 43 177 2.1E-53 T 28-03-2018 CIG75_RS09305 7acb2be25f766317444b158e25de758a 424 Gene3D G3DSA:3.40.50.720 191 424 7.7E-76 T 28-03-2018 CIG75_RS09305 7acb2be25f766317444b158e25de758a 424 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 110 123 - T 28-03-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CIG75_RS09305 7acb2be25f766317444b158e25de758a 424 SMART SM00839 193 422 3.1E-94 T 28-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CIG75_RS09305 7acb2be25f766317444b158e25de758a 424 SUPERFAMILY SSF51735 191 423 7.32E-77 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS09305 7acb2be25f766317444b158e25de758a 424 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 182 204 4.5E-31 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CIG75_RS09305 7acb2be25f766317444b158e25de758a 424 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 102 116 4.5E-31 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CIG75_RS09305 7acb2be25f766317444b158e25de758a 424 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 350 361 4.5E-31 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CIG75_RS09305 7acb2be25f766317444b158e25de758a 424 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 224 244 4.5E-31 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CIG75_RS09305 7acb2be25f766317444b158e25de758a 424 SUPERFAMILY SSF53223 15 193 7.68E-67 T 28-03-2018 CIG75_RS09305 7acb2be25f766317444b158e25de758a 424 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 46 173 6.2E-56 T 28-03-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CIG75_RS09305 7acb2be25f766317444b158e25de758a 424 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 191 422 2.1E-75 T 28-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CIG75_RS09305 7acb2be25f766317444b158e25de758a 424 PIRSF PIRSF000185 7 424 1.2E-168 T 28-03-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 CIG75_RS07975 10d3a4e811cd39df2fab01f8ea72fab3 334 SUPERFAMILY SSF56112 10 298 1.79E-23 T 28-03-2018 IPR011009 Protein kinase-like domain CIG75_RS07975 10d3a4e811cd39df2fab01f8ea72fab3 334 Gene3D G3DSA:3.90.1200.10 106 320 5.5E-10 T 28-03-2018 CIG75_RS07975 10d3a4e811cd39df2fab01f8ea72fab3 334 Gene3D G3DSA:3.30.200.20 1 95 8.5E-8 T 28-03-2018 CIG75_RS14570 79b19cccaef78c49b29bb3a2d2e6129b 590 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 9 423 5.5E-129 T 28-03-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 CIG75_RS14570 79b19cccaef78c49b29bb3a2d2e6129b 590 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 5 441 9.5E-95 T 28-03-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 CIG75_RS14570 79b19cccaef78c49b29bb3a2d2e6129b 590 Gene3D G3DSA:3.40.1670.10 459 569 5.4E-12 T 28-03-2018 CIG75_RS14570 79b19cccaef78c49b29bb3a2d2e6129b 590 Gene3D G3DSA:3.40.1670.10 317 458 2.8E-28 T 28-03-2018 CIG75_RS14570 79b19cccaef78c49b29bb3a2d2e6129b 590 SUPERFAMILY SSF143968 318 443 6.93E-28 T 28-03-2018 CIG75_RS14570 79b19cccaef78c49b29bb3a2d2e6129b 590 SUPERFAMILY SSF143968 495 585 1.31E-10 T 28-03-2018 CIG75_RS14570 79b19cccaef78c49b29bb3a2d2e6129b 590 SUPERFAMILY SSF50475 3 316 5.1E-95 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CIG75_RS07085 53aeefea934d05f30466926e48663a23 819 SUPERFAMILY SSF52374 5 227 6.08E-152 T 28-03-2018 CIG75_RS07085 53aeefea934d05f30466926e48663a23 819 SUPERFAMILY SSF52374 419 630 6.08E-152 T 28-03-2018 CIG75_RS07085 53aeefea934d05f30466926e48663a23 819 SUPERFAMILY SSF50677 227 416 2.41E-55 T 28-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CIG75_RS07085 53aeefea934d05f30466926e48663a23 819 Pfam PF09334 tRNA synthetases class I (M) 42 182 2.7E-20 T 28-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 CIG75_RS07085 53aeefea934d05f30466926e48663a23 819 Gene3D G3DSA:3.90.740.10 232 405 8.0E-53 T 28-03-2018 CIG75_RS07085 53aeefea934d05f30466926e48663a23 819 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 5 818 23.119 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CIG75_RS07085 53aeefea934d05f30466926e48663a23 819 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 421 621 9.7E-24 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CIG75_RS07085 53aeefea934d05f30466926e48663a23 819 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 222 407 5.7E-72 T 28-03-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 CIG75_RS07085 53aeefea934d05f30466926e48663a23 819 PRINTS PR00985 Leucyl-tRNA synthetase signature 530 552 6.1E-54 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CIG75_RS07085 53aeefea934d05f30466926e48663a23 819 PRINTS PR00985 Leucyl-tRNA synthetase signature 128 145 6.1E-54 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CIG75_RS07085 53aeefea934d05f30466926e48663a23 819 PRINTS PR00985 Leucyl-tRNA synthetase signature 491 509 6.1E-54 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CIG75_RS07085 53aeefea934d05f30466926e48663a23 819 PRINTS PR00985 Leucyl-tRNA synthetase signature 563 573 6.1E-54 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CIG75_RS07085 53aeefea934d05f30466926e48663a23 819 PRINTS PR00985 Leucyl-tRNA synthetase signature 186 199 6.1E-54 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CIG75_RS07085 53aeefea934d05f30466926e48663a23 819 PRINTS PR00985 Leucyl-tRNA synthetase signature 154 170 6.1E-54 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CIG75_RS07085 53aeefea934d05f30466926e48663a23 819 PRINTS PR00985 Leucyl-tRNA synthetase signature 216 235 6.1E-54 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CIG75_RS07085 53aeefea934d05f30466926e48663a23 819 Gene3D G3DSA:3.40.50.620 406 609 7.0E-71 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CIG75_RS07085 53aeefea934d05f30466926e48663a23 819 Gene3D G3DSA:3.40.50.620 1 231 2.4E-75 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CIG75_RS07085 53aeefea934d05f30466926e48663a23 819 SUPERFAMILY SSF47323 624 818 5.61E-36 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CIG75_RS07085 53aeefea934d05f30466926e48663a23 819 Gene3D G3DSA:1.10.730.10 610 755 3.6E-34 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CIG75_RS07085 53aeefea934d05f30466926e48663a23 819 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 7 576 7.2E-275 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CIG75_RS07085 53aeefea934d05f30466926e48663a23 819 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 43 54 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CIG75_RS07085 53aeefea934d05f30466926e48663a23 819 Pfam PF08264 Anticodon-binding domain of tRNA 663 780 1.3E-18 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CIG75_RS01785 0c6bfec5f9f53693447419c6c2635266 429 SMART SM00028 388 421 330.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS01785 0c6bfec5f9f53693447419c6c2635266 429 SMART SM00028 348 381 97.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS01785 0c6bfec5f9f53693447419c6c2635266 429 SMART SM00028 190 223 0.067 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS01785 0c6bfec5f9f53693447419c6c2635266 429 SMART SM00028 108 141 28.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS01785 0c6bfec5f9f53693447419c6c2635266 429 SMART SM00028 270 303 31.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS01785 0c6bfec5f9f53693447419c6c2635266 429 SMART SM00028 148 181 45.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS01785 0c6bfec5f9f53693447419c6c2635266 429 SMART SM00028 310 343 0.0035 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS01785 0c6bfec5f9f53693447419c6c2635266 429 SMART SM00028 230 263 2.7E-4 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS01785 0c6bfec5f9f53693447419c6c2635266 429 Pfam PF13432 Tetratricopeptide repeat 75 135 2.3E-4 T 28-03-2018 CIG75_RS01785 0c6bfec5f9f53693447419c6c2635266 429 SMART SM00530 7 61 8.4E-12 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS01785 0c6bfec5f9f53693447419c6c2635266 429 SUPERFAMILY SSF47413 3 62 5.63E-14 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CIG75_RS01785 0c6bfec5f9f53693447419c6c2635266 429 SUPERFAMILY SSF48452 125 342 5.5E-26 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS01785 0c6bfec5f9f53693447419c6c2635266 429 Gene3D G3DSA:1.25.40.10 159 196 3.2E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS01785 0c6bfec5f9f53693447419c6c2635266 429 Gene3D G3DSA:1.25.40.10 241 280 1.5E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS01785 0c6bfec5f9f53693447419c6c2635266 429 Pfam PF13424 Tetratricopeptide repeat 275 337 3.0E-7 T 28-03-2018 CIG75_RS01785 0c6bfec5f9f53693447419c6c2635266 429 Pfam PF13424 Tetratricopeptide repeat 191 262 2.8E-9 T 28-03-2018 CIG75_RS01785 0c6bfec5f9f53693447419c6c2635266 429 Gene3D G3DSA:1.25.40.10 321 423 1.6E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS01785 0c6bfec5f9f53693447419c6c2635266 429 Pfam PF13374 Tetratricopeptide repeat 347 377 0.015 T 28-03-2018 CIG75_RS01785 0c6bfec5f9f53693447419c6c2635266 429 Gene3D G3DSA:1.10.150.160 197 240 1.5E-9 T 28-03-2018 CIG75_RS01785 0c6bfec5f9f53693447419c6c2635266 429 Gene3D G3DSA:1.25.40.10 84 106 0.074 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS01785 0c6bfec5f9f53693447419c6c2635266 429 Pfam PF12844 Helix-turn-helix domain 5 63 4.2E-11 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS01785 0c6bfec5f9f53693447419c6c2635266 429 Gene3D G3DSA:1.10.150.200 107 158 6.1E-6 T 28-03-2018 CIG75_RS01785 0c6bfec5f9f53693447419c6c2635266 429 Gene3D G3DSA:1.10.150.200 281 320 4.9E-6 T 28-03-2018 CIG75_RS01785 0c6bfec5f9f53693447419c6c2635266 429 Gene3D G3DSA:1.10.3100.10 2 83 1.7E-16 T 28-03-2018 IPR027910 YdiL-like domain CIG75_RS18370 3991371b93db9c7f474ac5b8991f427f 242 SUPERFAMILY SSF56712 13 229 5.1E-58 T 28-03-2018 IPR023405 DNA topoisomerase, type IA, core domain CIG75_RS18370 3991371b93db9c7f474ac5b8991f427f 242 Pfam PF01131 DNA topoisomerase 16 229 2.9E-53 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CIG75_RS18370 3991371b93db9c7f474ac5b8991f427f 242 Gene3D G3DSA:1.10.460.10 55 232 1.4E-27 T 28-03-2018 CIG75_RS18370 3991371b93db9c7f474ac5b8991f427f 242 SMART SM00437 2 195 1.1E-21 T 28-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 CIG75_RS18370 3991371b93db9c7f474ac5b8991f427f 242 Gene3D G3DSA:1.10.290.10 5 54 9.1E-8 T 28-03-2018 CIG75_RS18370 3991371b93db9c7f474ac5b8991f427f 242 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 50 66 9.6E-12 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CIG75_RS18370 3991371b93db9c7f474ac5b8991f427f 242 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 158 172 9.6E-12 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CIG75_RS14415 4fa2bf0c0da3b6c113e2150c86e6b936 230 Gene3D G3DSA:3.40.1080.10 1 230 3.3E-101 T 28-03-2018 CIG75_RS14415 4fa2bf0c0da3b6c113e2150c86e6b936 230 SMART SM00882 5 216 1.2E-100 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CIG75_RS14415 4fa2bf0c0da3b6c113e2150c86e6b936 230 ProSitePatterns PS01273 Coenzyme A transferases signature 1. 17 32 - T 28-03-2018 IPR004163 Coenzyme A transferase binding site GO:0008152|GO:0008410 Reactome: R-HSA-77108 CIG75_RS14415 4fa2bf0c0da3b6c113e2150c86e6b936 230 Pfam PF01144 Coenzyme A transferase 6 215 5.1E-83 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CIG75_RS14415 4fa2bf0c0da3b6c113e2150c86e6b936 230 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 1 215 5.3E-89 T 28-03-2018 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 Reactome: R-HSA-77108 CIG75_RS14415 4fa2bf0c0da3b6c113e2150c86e6b936 230 SUPERFAMILY SSF100950 2 224 2.03E-92 T 28-03-2018 CIG75_RS02620 ae41bf6de9c23bcba4c614ea467c520e 423 Gene3D G3DSA:3.40.50.10490 193 419 1.0E-69 T 28-03-2018 CIG75_RS02620 ae41bf6de9c23bcba4c614ea467c520e 423 SUPERFAMILY SSF53697 24 420 1.52E-112 T 28-03-2018 CIG75_RS02620 ae41bf6de9c23bcba4c614ea467c520e 423 Pfam PF00342 Phosphoglucose isomerase 71 412 2.0E-24 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS02620 ae41bf6de9c23bcba4c614ea467c520e 423 PRINTS PR00662 Glucose-6-phosphate isomerase signature 71 90 3.8E-20 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS02620 ae41bf6de9c23bcba4c614ea467c520e 423 PRINTS PR00662 Glucose-6-phosphate isomerase signature 183 201 3.8E-20 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS02620 ae41bf6de9c23bcba4c614ea467c520e 423 PRINTS PR00662 Glucose-6-phosphate isomerase signature 361 379 3.8E-20 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS02620 ae41bf6de9c23bcba4c614ea467c520e 423 PRINTS PR00662 Glucose-6-phosphate isomerase signature 258 279 3.8E-20 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS02620 ae41bf6de9c23bcba4c614ea467c520e 423 PRINTS PR00662 Glucose-6-phosphate isomerase signature 393 406 3.8E-20 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS02620 ae41bf6de9c23bcba4c614ea467c520e 423 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 6 420 22.637 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS02620 ae41bf6de9c23bcba4c614ea467c520e 423 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 393 410 - T 28-03-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS02620 ae41bf6de9c23bcba4c614ea467c520e 423 Gene3D G3DSA:3.40.50.10490 51 192 5.7E-36 T 28-03-2018 CIG75_RS12320 e9bef29db049768fc5bdf2b0299fd2a0 451 SMART SM00962 100 295 1.1E-117 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CIG75_RS12320 e9bef29db049768fc5bdf2b0299fd2a0 451 SUPERFAMILY SSF52540 43 353 9.67E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS12320 e9bef29db049768fc5bdf2b0299fd2a0 451 SMART SM00382 99 273 2.3E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS12320 e9bef29db049768fc5bdf2b0299fd2a0 451 SUPERFAMILY SSF47446 326 429 2.13E-37 T 28-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CIG75_RS12320 e9bef29db049768fc5bdf2b0299fd2a0 451 Gene3D G3DSA:3.40.50.300 96 296 8.1E-41 T 28-03-2018 CIG75_RS12320 e9bef29db049768fc5bdf2b0299fd2a0 451 Pfam PF02978 Signal peptide binding domain 327 426 4.6E-34 T 28-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CIG75_RS12320 e9bef29db049768fc5bdf2b0299fd2a0 451 Gene3D G3DSA:1.20.120.140 1 92 7.2E-31 T 28-03-2018 CIG75_RS12320 e9bef29db049768fc5bdf2b0299fd2a0 451 TIGRFAM TIGR00959 ffh: signal recognition particle protein 3 428 2.1E-188 T 28-03-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 CIG75_RS12320 e9bef29db049768fc5bdf2b0299fd2a0 451 Pfam PF02881 SRP54-type protein, helical bundle domain 6 83 6.9E-24 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CIG75_RS12320 e9bef29db049768fc5bdf2b0299fd2a0 451 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 6 436 34.429 T 28-03-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 CIG75_RS12320 e9bef29db049768fc5bdf2b0299fd2a0 451 Gene3D G3DSA:1.10.260.30 326 431 3.7E-39 T 28-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CIG75_RS12320 e9bef29db049768fc5bdf2b0299fd2a0 451 SMART SM00963 2 87 5.3E-38 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CIG75_RS12320 e9bef29db049768fc5bdf2b0299fd2a0 451 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 268 281 - T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CIG75_RS12320 e9bef29db049768fc5bdf2b0299fd2a0 451 Pfam PF00448 SRP54-type protein, GTPase domain 100 295 1.2E-76 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CIG75_RS16745 9e8c8ed177bc82ceadee2c56364fcf69 236 Pfam PF02146 Sir2 family 22 191 4.0E-49 T 28-03-2018 IPR003000 Sirtuin family GO:0070403 CIG75_RS16745 9e8c8ed177bc82ceadee2c56364fcf69 236 Gene3D G3DSA:3.40.50.1220 1 236 7.6E-68 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CIG75_RS16745 9e8c8ed177bc82ceadee2c56364fcf69 236 SUPERFAMILY SSF52467 2 236 1.96E-79 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CIG75_RS10895 3ab808059d06566c4492c471a1731f76 207 Gene3D G3DSA:3.20.20.70 1 207 9.9E-64 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CIG75_RS10895 3ab808059d06566c4492c471a1731f76 207 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 2 206 35.578 T 28-03-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 CIG75_RS10895 3ab808059d06566c4492c471a1731f76 207 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 5 201 1.3E-45 T 28-03-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 CIG75_RS10895 3ab808059d06566c4492c471a1731f76 207 SUPERFAMILY SSF51366 2 204 5.02E-50 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CIG75_RS03440 03892aec9b4a1280758f4742d57d8f91 414 Gene3D G3DSA:3.30.470.20 191 401 4.9E-27 T 28-03-2018 CIG75_RS03440 03892aec9b4a1280758f4742d57d8f91 414 SUPERFAMILY SSF56059 102 325 2.3E-36 T 28-03-2018 CIG75_RS03440 03892aec9b4a1280758f4742d57d8f91 414 Gene3D G3DSA:3.30.1490.20 113 190 1.4E-18 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CIG75_RS03440 03892aec9b4a1280758f4742d57d8f91 414 Gene3D G3DSA:3.40.50.20 2 112 1.7E-8 T 28-03-2018 CIG75_RS03440 03892aec9b4a1280758f4742d57d8f91 414 Pfam PF13535 ATP-grasp domain 145 292 1.9E-26 T 28-03-2018 CIG75_RS03440 03892aec9b4a1280758f4742d57d8f91 414 SMART SM01209 109 289 0.0025 T 28-03-2018 CIG75_RS01610 507ab7e09807b9401261064b5cb0ae4c 283 SUPERFAMILY SSF51735 1 185 1.97E-61 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS01610 507ab7e09807b9401261064b5cb0ae4c 283 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 183 208 - T 28-03-2018 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CIG75_RS01610 507ab7e09807b9401261064b5cb0ae4c 283 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 5 183 5.3E-65 T 28-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CIG75_RS01610 507ab7e09807b9401261064b5cb0ae4c 283 Gene3D G3DSA:1.10.1040.10 186 283 4.4E-36 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CIG75_RS01610 507ab7e09807b9401261064b5cb0ae4c 283 Gene3D G3DSA:3.40.50.720 1 185 4.3E-57 T 28-03-2018 CIG75_RS01610 507ab7e09807b9401261064b5cb0ae4c 283 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 186 282 6.6E-37 T 28-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CIG75_RS01610 507ab7e09807b9401261064b5cb0ae4c 283 SUPERFAMILY SSF48179 185 283 2.38E-35 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CIG75_RS01610 507ab7e09807b9401261064b5cb0ae4c 283 PIRSF PIRSF000105 1 283 1.2E-92 T 28-03-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 CIG75_RS14815 3a7ae7074809f2833bd87b23a4c05b42 184 PRINTS PR00773 GrpE protein signature 163 182 7.7E-27 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CIG75_RS14815 3a7ae7074809f2833bd87b23a4c05b42 184 PRINTS PR00773 GrpE protein signature 136 151 7.7E-27 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CIG75_RS14815 3a7ae7074809f2833bd87b23a4c05b42 184 PRINTS PR00773 GrpE protein signature 83 98 7.7E-27 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CIG75_RS14815 3a7ae7074809f2833bd87b23a4c05b42 184 PRINTS PR00773 GrpE protein signature 55 71 7.7E-27 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CIG75_RS14815 3a7ae7074809f2833bd87b23a4c05b42 184 Hamap MF_01151 Protein GrpE [grpE]. 4 184 19.953 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CIG75_RS14815 3a7ae7074809f2833bd87b23a4c05b42 184 SUPERFAMILY SSF58014 34 128 1.19E-24 T 28-03-2018 CIG75_RS14815 3a7ae7074809f2833bd87b23a4c05b42 184 Gene3D G3DSA:2.30.22.10 128 184 2.7E-20 T 28-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 CIG75_RS14815 3a7ae7074809f2833bd87b23a4c05b42 184 Pfam PF01025 GrpE 24 184 8.9E-51 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CIG75_RS14815 3a7ae7074809f2833bd87b23a4c05b42 184 Gene3D G3DSA:3.90.20.20 2 126 9.4E-23 T 28-03-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 CIG75_RS14815 3a7ae7074809f2833bd87b23a4c05b42 184 SUPERFAMILY SSF51064 130 184 5.49E-17 T 28-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 CIG75_RS16810 b612d0494df2070a80ce7bbfa003360d 430 SUPERFAMILY SSF48452 78 177 2.91E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS16810 b612d0494df2070a80ce7bbfa003360d 430 Gene3D G3DSA:1.10.150.200 241 284 0.0041 T 28-03-2018 CIG75_RS16810 b612d0494df2070a80ce7bbfa003360d 430 Pfam PF13424 Tetratricopeptide repeat 193 257 2.1E-8 T 28-03-2018 CIG75_RS16810 b612d0494df2070a80ce7bbfa003360d 430 Gene3D G3DSA:1.25.40.10 66 157 1.5E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS16810 b612d0494df2070a80ce7bbfa003360d 430 Pfam PF01381 Helix-turn-helix 11 64 2.1E-11 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS16810 b612d0494df2070a80ce7bbfa003360d 430 SMART SM00028 193 226 0.11 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS16810 b612d0494df2070a80ce7bbfa003360d 430 SMART SM00028 349 382 290.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS16810 b612d0494df2070a80ce7bbfa003360d 430 SMART SM00028 231 264 0.5 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS16810 b612d0494df2070a80ce7bbfa003360d 430 Gene3D G3DSA:1.25.40.10 158 240 8.1E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS16810 b612d0494df2070a80ce7bbfa003360d 430 SMART SM00530 10 64 1.0E-12 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS16810 b612d0494df2070a80ce7bbfa003360d 430 SUPERFAMILY SSF47413 5 65 1.13E-14 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CIG75_RS16810 b612d0494df2070a80ce7bbfa003360d 430 Gene3D G3DSA:1.25.40.10 285 406 1.8E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS16810 b612d0494df2070a80ce7bbfa003360d 430 Gene3D G3DSA:1.10.260.40 4 65 6.6E-15 T 28-03-2018 CIG75_RS16810 b612d0494df2070a80ce7bbfa003360d 430 SUPERFAMILY SSF48452 176 388 1.33E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS10990 3f4d35dd752cde872aa3f4f5f9b138ce 662 TIGRFAM TIGR03604 TOMM_cyclo_SagD: thiazole/oxazole-forming peptide maturase, SagD family component 270 662 3.2E-101 T 28-03-2018 IPR027624 Thiazole/oxazole-forming peptide maturase, SagD family component CIG75_RS10990 3f4d35dd752cde872aa3f4f5f9b138ce 662 Gene3D G3DSA:3.40.50.720 13 191 3.0E-4 T 28-03-2018 CIG75_RS10990 3f4d35dd752cde872aa3f4f5f9b138ce 662 TIGRFAM TIGR03882 cyclo_dehyd_2: bacteriocin biosynthesis cyclodehydratase domain 72 238 1.5E-22 T 28-03-2018 IPR022291 Bacteriocin biosynthesis, cyclodehydratase domain CIG75_RS10990 3f4d35dd752cde872aa3f4f5f9b138ce 662 Pfam PF02624 YcaO cyclodehydratase, ATP-ad Mg2+-binding 270 618 1.2E-82 T 28-03-2018 IPR003776 YcaO-like domain CIG75_RS08600 7d18ddb8050fa06502ccbb6496e6858d 195 Gene3D G3DSA:1.10.357.10 64 195 4.2E-8 T 28-03-2018 CIG75_RS08600 7d18ddb8050fa06502ccbb6496e6858d 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 8.2E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CIG75_RS08600 7d18ddb8050fa06502ccbb6496e6858d 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 8.2E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CIG75_RS08600 7d18ddb8050fa06502ccbb6496e6858d 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 58 1.2E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CIG75_RS08600 7d18ddb8050fa06502ccbb6496e6858d 195 Gene3D G3DSA:1.10.10.60 5 63 1.9E-12 T 28-03-2018 CIG75_RS08600 7d18ddb8050fa06502ccbb6496e6858d 195 SUPERFAMILY SSF46689 6 76 2.34E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CIG75_RS15785 e3487140be4d9c0f59e588588470dfbd 388 Pfam PF00155 Aminotransferase class I and II 33 382 9.4E-63 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CIG75_RS15785 e3487140be4d9c0f59e588588470dfbd 388 Gene3D G3DSA:3.90.1150.10 255 387 1.1E-37 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CIG75_RS15785 e3487140be4d9c0f59e588588470dfbd 388 SUPERFAMILY SSF53383 6 386 4.95E-106 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CIG75_RS15785 e3487140be4d9c0f59e588588470dfbd 388 Gene3D G3DSA:3.90.1150.10 5 254 4.7E-33 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CIG75_RS09610 d67c13a834308557cff57f3e3cc27e39 494 Gene3D G3DSA:3.10.170.10 176 347 9.3E-12 T 28-03-2018 CIG75_RS09610 d67c13a834308557cff57f3e3cc27e39 494 Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif 54 98 9.3E-7 T 28-03-2018 IPR011096 FTP domain CIG75_RS09610 d67c13a834308557cff57f3e3cc27e39 494 SUPERFAMILY SSF55486 249 491 3.33E-40 T 28-03-2018 CIG75_RS09610 d67c13a834308557cff57f3e3cc27e39 494 Gene3D G3DSA:1.10.390.10 351 493 1.3E-20 T 28-03-2018 CIG75_RS09610 d67c13a834308557cff57f3e3cc27e39 494 Pfam PF02128 Fungalysin metallopeptidase (M36) 291 491 1.3E-8 T 28-03-2018 IPR001842 Peptidase M36, fungalysin GO:0004222|GO:0005615|GO:0008270 CIG75_RS12295 73e0dbeb3c4c3294b768c4dcd6f8b258 246 Gene3D G3DSA:3.40.1280.10 1 168 1.0E-75 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CIG75_RS12295 73e0dbeb3c4c3294b768c4dcd6f8b258 246 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 23 220 1.1E-68 T 28-03-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CIG75_RS12295 73e0dbeb3c4c3294b768c4dcd6f8b258 246 PIRSF PIRSF000386 1 245 1.0E-103 T 28-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CIG75_RS12295 73e0dbeb3c4c3294b768c4dcd6f8b258 246 Gene3D G3DSA:1.10.1270.20 169 246 2.5E-34 T 28-03-2018 CIG75_RS12295 73e0dbeb3c4c3294b768c4dcd6f8b258 246 SUPERFAMILY SSF75217 2 243 2.29E-100 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CIG75_RS12295 73e0dbeb3c4c3294b768c4dcd6f8b258 246 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 232 8.1E-97 T 28-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CIG75_RS12295 73e0dbeb3c4c3294b768c4dcd6f8b258 246 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 246 109.52 T 28-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CIG75_RS12005 9210d79eb9e13dda91168cd92cc5efaa 334 PIRSF PIRSF002888 1 334 8.5E-112 T 28-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CIG75_RS12005 9210d79eb9e13dda91168cd92cc5efaa 334 SUPERFAMILY SSF101801 251 328 3.79E-16 T 28-03-2018 IPR001543 Surface presentation of antigen (SpoA) CIG75_RS12005 9210d79eb9e13dda91168cd92cc5efaa 334 PRINTS PR00955 Flagellar motor switch protein FliM signature 211 229 6.8E-28 T 28-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CIG75_RS12005 9210d79eb9e13dda91168cd92cc5efaa 334 PRINTS PR00955 Flagellar motor switch protein FliM signature 90 106 6.8E-28 T 28-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CIG75_RS12005 9210d79eb9e13dda91168cd92cc5efaa 334 PRINTS PR00955 Flagellar motor switch protein FliM signature 115 134 6.8E-28 T 28-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CIG75_RS12005 9210d79eb9e13dda91168cd92cc5efaa 334 PRINTS PR00955 Flagellar motor switch protein FliM signature 2 15 6.8E-28 T 28-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CIG75_RS12005 9210d79eb9e13dda91168cd92cc5efaa 334 Pfam PF02154 Flagellar motor switch protein FliM 39 229 1.4E-72 T 28-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CIG75_RS12005 9210d79eb9e13dda91168cd92cc5efaa 334 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 254 323 2.1E-18 T 28-03-2018 IPR001543 Surface presentation of antigen (SpoA) CIG75_RS12005 9210d79eb9e13dda91168cd92cc5efaa 334 TIGRFAM TIGR01397 fliM_switch: flagellar motor switch protein FliM 3 324 9.5E-112 T 28-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CIG75_RS12005 9210d79eb9e13dda91168cd92cc5efaa 334 SUPERFAMILY SSF103039 45 230 6.89E-32 T 28-03-2018 IPR028976 CheC-like domain CIG75_RS12005 9210d79eb9e13dda91168cd92cc5efaa 334 Gene3D G3DSA:2.30.330.10 240 332 6.9E-19 T 28-03-2018 IPR001543 Surface presentation of antigen (SpoA) CIG75_RS12005 9210d79eb9e13dda91168cd92cc5efaa 334 Gene3D G3DSA:3.40.1550.10 47 236 9.2E-49 T 28-03-2018 IPR028976 CheC-like domain CIG75_RS18475 629f2ebc4066740e96a988fc60346555 639 Pfam PF02719 Polysaccharide biosynthesis protein 285 566 8.2E-122 T 28-03-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain CIG75_RS18475 629f2ebc4066740e96a988fc60346555 639 SUPERFAMILY SSF51735 283 545 3.78E-60 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS18475 629f2ebc4066740e96a988fc60346555 639 Gene3D G3DSA:3.40.50.720 158 266 2.9E-26 T 28-03-2018 CIG75_RS18475 629f2ebc4066740e96a988fc60346555 639 SUPERFAMILY SSF53335 107 307 1.35E-14 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CIG75_RS18475 629f2ebc4066740e96a988fc60346555 639 Gene3D G3DSA:3.40.50.720 131 157 0.46 T 28-03-2018 CIG75_RS18475 629f2ebc4066740e96a988fc60346555 639 Gene3D G3DSA:3.40.50.720 278 608 4.5E-67 T 28-03-2018 CIG75_RS18475 629f2ebc4066740e96a988fc60346555 639 Pfam PF13727 CoA-binding domain 73 238 2.4E-9 T 28-03-2018 CIG75_RS03530 d27f32f877bc5485a614bb1a71d335eb 228 Pfam PF00072 Response regulator receiver domain 4 115 2.6E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CIG75_RS03530 d27f32f877bc5485a614bb1a71d335eb 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 178 194 2.9E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CIG75_RS03530 d27f32f877bc5485a614bb1a71d335eb 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 178 2.9E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CIG75_RS03530 d27f32f877bc5485a614bb1a71d335eb 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 194 206 2.9E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CIG75_RS03530 d27f32f877bc5485a614bb1a71d335eb 228 Pfam PF00196 Bacterial regulatory proteins, luxR family 163 218 1.7E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CIG75_RS03530 d27f32f877bc5485a614bb1a71d335eb 228 SMART SM00421 161 218 7.2E-26 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CIG75_RS03530 d27f32f877bc5485a614bb1a71d335eb 228 SUPERFAMILY SSF52172 1 128 2.7E-34 T 28-03-2018 IPR011006 CheY-like superfamily CIG75_RS03530 d27f32f877bc5485a614bb1a71d335eb 228 Gene3D G3DSA:3.40.50.2300 1 126 6.4E-34 T 28-03-2018 CIG75_RS03530 d27f32f877bc5485a614bb1a71d335eb 228 ProSitePatterns PS00622 LuxR-type HTH domain signature. 178 205 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CIG75_RS03530 d27f32f877bc5485a614bb1a71d335eb 228 SMART SM00448 2 115 1.6E-31 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CIG75_RS03530 d27f32f877bc5485a614bb1a71d335eb 228 Gene3D G3DSA:1.10.10.10 127 228 4.9E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS03530 d27f32f877bc5485a614bb1a71d335eb 228 SUPERFAMILY SSF46894 156 224 1.8E-22 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CIG75_RS04460 8238bd69767569280f9bf9063642f3eb 171 Pfam PF08281 Sigma-70, region 4 107 160 4.3E-15 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS04460 8238bd69767569280f9bf9063642f3eb 171 SUPERFAMILY SSF88946 11 96 5.49E-19 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS04460 8238bd69767569280f9bf9063642f3eb 171 SUPERFAMILY SSF88659 103 163 2.24E-14 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS04460 8238bd69767569280f9bf9063642f3eb 171 Gene3D G3DSA:1.10.10.10 87 169 2.2E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS04460 8238bd69767569280f9bf9063642f3eb 171 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 13 161 1.1E-31 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS04460 8238bd69767569280f9bf9063642f3eb 171 Gene3D G3DSA:1.10.1740.10 5 86 1.5E-17 T 28-03-2018 CIG75_RS04460 8238bd69767569280f9bf9063642f3eb 171 Pfam PF04542 Sigma-70 region 2 19 84 9.4E-12 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS15200 91f05f49fe6d435222a8fc0e559c4d5d 289 Gene3D G3DSA:3.40.50.970 9 72 1.8E-16 T 28-03-2018 CIG75_RS15200 91f05f49fe6d435222a8fc0e559c4d5d 289 Gene3D G3DSA:3.40.50.970 73 289 1.2E-47 T 28-03-2018 CIG75_RS15200 91f05f49fe6d435222a8fc0e559c4d5d 289 Pfam PF12367 Pyruvate ferredoxin oxidoreductase beta subunit C terminal 200 265 4.0E-22 T 28-03-2018 IPR032686 Pyruvate ferredoxin oxidoreductase beta subunit, C-terminal CIG75_RS15200 91f05f49fe6d435222a8fc0e559c4d5d 289 TIGRFAM TIGR02177 PorB_KorB: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family 14 282 1.7E-99 T 28-03-2018 IPR011896 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate CIG75_RS15200 91f05f49fe6d435222a8fc0e559c4d5d 289 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 48 196 4.5E-32 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CIG75_RS15200 91f05f49fe6d435222a8fc0e559c4d5d 289 SUPERFAMILY SSF52518 13 270 3.46E-77 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CIG75_RS01125 3d6feea4f2e5d3a0c69ab35bec83977e 634 SMART SM00487 9 207 2.9E-59 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CIG75_RS01125 3d6feea4f2e5d3a0c69ab35bec83977e 634 Pfam PF00270 DEAD/DEAH box helicase 14 181 1.1E-49 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CIG75_RS01125 3d6feea4f2e5d3a0c69ab35bec83977e 634 SMART SM00490 243 324 7.5E-34 T 28-03-2018 IPR001650 Helicase, C-terminal CIG75_RS01125 3d6feea4f2e5d3a0c69ab35bec83977e 634 Gene3D G3DSA:3.40.50.300 3 207 6.5E-60 T 28-03-2018 CIG75_RS01125 3d6feea4f2e5d3a0c69ab35bec83977e 634 Pfam PF00271 Helicase conserved C-terminal domain 217 324 9.2E-31 T 28-03-2018 IPR001650 Helicase, C-terminal CIG75_RS01125 3d6feea4f2e5d3a0c69ab35bec83977e 634 Gene3D G3DSA:3.40.50.300 208 366 2.9E-44 T 28-03-2018 CIG75_RS01125 3d6feea4f2e5d3a0c69ab35bec83977e 634 SUPERFAMILY SSF52540 59 345 4.95E-75 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS11465 55aae13176bdbb93945f81df94ff9d8c 281 Hamap MF_00662 Phosphatidylserine decarboxylase proenzyme [psd]. 7 279 40.404 T 28-03-2018 IPR033178 Phosphatidylserine decarboxylase, prokaryotic type 1 GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 CIG75_RS11465 55aae13176bdbb93945f81df94ff9d8c 281 Pfam PF02666 Phosphatidylserine decarboxylase 61 276 4.6E-61 T 28-03-2018 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 CIG75_RS11465 55aae13176bdbb93945f81df94ff9d8c 281 TIGRFAM TIGR00163 PS_decarb: phosphatidylserine decarboxylase 47 277 1.0E-67 T 28-03-2018 IPR033177 Phosphatidylserine decarboxylase GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 CIG75_RS17070 2afe4dda03a571ddbcd17f4f9fb52050 252 Gene3D G3DSA:3.20.20.70 1 252 1.1E-102 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CIG75_RS17070 2afe4dda03a571ddbcd17f4f9fb52050 252 ProSitePatterns PS00171 Triosephosphate isomerase active site. 165 175 - T 28-03-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS17070 2afe4dda03a571ddbcd17f4f9fb52050 252 SUPERFAMILY SSF51351 1 248 9.56E-95 T 28-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS17070 2afe4dda03a571ddbcd17f4f9fb52050 252 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 2 250 40.539 T 28-03-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS17070 2afe4dda03a571ddbcd17f4f9fb52050 252 Pfam PF00121 Triosephosphate isomerase 5 246 3.5E-94 T 28-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS17070 2afe4dda03a571ddbcd17f4f9fb52050 252 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 6 239 8.1E-54 T 28-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS04735 d52614da7f08bcceb899d1d0be2de533 249 Pfam PF12730 ABC-2 family transporter protein 5 183 1.1E-20 T 28-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 CIG75_RS00155 0871592ccf38d419c26013ef5644ed34 486 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 10 485 87.605 T 28-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 CIG75_RS00155 0871592ccf38d419c26013ef5644ed34 486 SMART SM01240 9 472 0.0 T 28-03-2018 CIG75_RS00155 0871592ccf38d419c26013ef5644ed34 486 SMART SM00116 159 207 6.5E-9 T 28-03-2018 IPR000644 CBS domain CIG75_RS00155 0871592ccf38d419c26013ef5644ed34 486 SMART SM00116 98 146 2.0E-8 T 28-03-2018 IPR000644 CBS domain CIG75_RS00155 0871592ccf38d419c26013ef5644ed34 486 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 296 308 - T 28-03-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 CIG75_RS00155 0871592ccf38d419c26013ef5644ed34 486 SUPERFAMILY SSF51412 7 92 3.4E-130 T 28-03-2018 CIG75_RS00155 0871592ccf38d419c26013ef5644ed34 486 SUPERFAMILY SSF51412 218 476 3.4E-130 T 28-03-2018 CIG75_RS00155 0871592ccf38d419c26013ef5644ed34 486 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 10 453 1.4E-200 T 28-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 CIG75_RS00155 0871592ccf38d419c26013ef5644ed34 486 SUPERFAMILY SSF54631 68 206 9.18E-32 T 28-03-2018 CIG75_RS00155 0871592ccf38d419c26013ef5644ed34 486 PIRSF PIRSF000130 1 486 8.5E-217 T 28-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 CIG75_RS00155 0871592ccf38d419c26013ef5644ed34 486 Gene3D G3DSA:3.20.20.70 4 481 1.4E-116 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CIG75_RS00155 0871592ccf38d419c26013ef5644ed34 486 Pfam PF00571 CBS domain 97 142 3.5E-10 T 28-03-2018 IPR000644 CBS domain CIG75_RS00155 0871592ccf38d419c26013ef5644ed34 486 Pfam PF00571 CBS domain 152 206 7.4E-8 T 28-03-2018 IPR000644 CBS domain CIG75_RS00155 0871592ccf38d419c26013ef5644ed34 486 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 10 472 2.9E-168 T 28-03-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 CIG75_RS02885 d77c7dadbe51524b33e17126c1785ccd 814 Pfam PF07581 The GLUG motif 684 705 0.0018 T 28-03-2018 IPR011493 GLUG CIG75_RS02885 d77c7dadbe51524b33e17126c1785ccd 814 Pfam PF07581 The GLUG motif 707 732 4.3E-4 T 28-03-2018 IPR011493 GLUG CIG75_RS02885 d77c7dadbe51524b33e17126c1785ccd 814 Pfam PF07581 The GLUG motif 658 680 6.9E-5 T 28-03-2018 IPR011493 GLUG CIG75_RS02885 d77c7dadbe51524b33e17126c1785ccd 814 Pfam PF00395 S-layer homology domain 34 75 5.0E-13 T 28-03-2018 IPR001119 S-layer homology domain CIG75_RS02885 d77c7dadbe51524b33e17126c1785ccd 814 Pfam PF00395 S-layer homology domain 92 135 9.8E-12 T 28-03-2018 IPR001119 S-layer homology domain CIG75_RS02885 d77c7dadbe51524b33e17126c1785ccd 814 Pfam PF00395 S-layer homology domain 154 195 1.3E-8 T 28-03-2018 IPR001119 S-layer homology domain CIG75_RS15115 195c60f107cb60e23fd0ffd08348b0c3 269 Pfam PF06182 ABC-2 family transporter protein 42 268 5.7E-23 T 28-03-2018 IPR010390 Protein of unknown function DUF990 CIG75_RS15335 b485731644fd6593fe341e839fdee497 276 Gene3D G3DSA:3.40.50.1000 1 16 0.056 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS15335 b485731644fd6593fe341e839fdee497 276 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 268 1.8E-51 T 28-03-2018 IPR000150 Cof family GO:0016787 CIG75_RS15335 b485731644fd6593fe341e839fdee497 276 Gene3D G3DSA:3.40.50.1000 17 276 4.9E-41 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS15335 b485731644fd6593fe341e839fdee497 276 SUPERFAMILY SSF56784 1 275 2.13E-68 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS15335 b485731644fd6593fe341e839fdee497 276 ProSitePatterns PS01229 Hypothetical cof family signature 2. 224 246 - T 28-03-2018 CIG75_RS15335 b485731644fd6593fe341e839fdee497 276 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 268 2.6E-60 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS15335 b485731644fd6593fe341e839fdee497 276 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 243 3.8E-28 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CIG75_RS01750 f44ddf84214fc8767503204ca10be3c0 374 Hamap MF_01692 N-acetyldiaminopimelate deacetylase. 1 370 63.202 T 28-03-2018 IPR023905 Acetyldiaminopimelate deacetylase GO:0009089|GO:0050118 KEGG: 00300+3.5.1.47|MetaCyc: PWY-2941 CIG75_RS01750 f44ddf84214fc8767503204ca10be3c0 374 PIRSF PIRSF005962 1 373 5.0E-109 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CIG75_RS01750 f44ddf84214fc8767503204ca10be3c0 374 SUPERFAMILY SSF55031 176 281 7.33E-28 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CIG75_RS01750 f44ddf84214fc8767503204ca10be3c0 374 Gene3D G3DSA:3.40.630.10 1 270 2.5E-54 T 28-03-2018 CIG75_RS01750 f44ddf84214fc8767503204ca10be3c0 374 SUPERFAMILY SSF53187 288 364 7.12E-67 T 28-03-2018 CIG75_RS01750 f44ddf84214fc8767503204ca10be3c0 374 SUPERFAMILY SSF53187 3 187 7.12E-67 T 28-03-2018 CIG75_RS01750 f44ddf84214fc8767503204ca10be3c0 374 Pfam PF07687 Peptidase dimerisation domain 178 267 4.3E-10 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CIG75_RS01750 f44ddf84214fc8767503204ca10be3c0 374 Pfam PF01546 Peptidase family M20/M25/M40 65 359 6.3E-27 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CIG75_RS01750 f44ddf84214fc8767503204ca10be3c0 374 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 5 359 2.4E-84 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CIG75_RS14790 ccb034f7c09fca76efead3718d3ade52 459 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 147 167 - T 28-03-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 CIG75_RS14790 ccb034f7c09fca76efead3718d3ade52 459 Gene3D G3DSA:3.80.30.20 140 375 1.2E-47 T 28-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe CIG75_RS14790 ccb034f7c09fca76efead3718d3ade52 459 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 3 422 1.4E-138 T 28-03-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 CIG75_RS14790 ccb034f7c09fca76efead3718d3ade52 459 Pfam PF04055 Radical SAM superfamily 149 319 5.3E-27 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CIG75_RS14790 ccb034f7c09fca76efead3718d3ade52 459 Pfam PF01938 TRAM domain 374 420 7.3E-5 T 28-03-2018 IPR002792 TRAM domain CIG75_RS14790 ccb034f7c09fca76efead3718d3ade52 459 Pfam PF00919 Uncharacterized protein family UPF0004 4 98 1.2E-27 T 28-03-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 CIG75_RS14790 ccb034f7c09fca76efead3718d3ade52 459 SMART SM00729 143 361 3.3E-58 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CIG75_RS14790 ccb034f7c09fca76efead3718d3ade52 459 SUPERFAMILY SSF102114 129 366 2.88E-54 T 28-03-2018 CIG75_RS14790 ccb034f7c09fca76efead3718d3ade52 459 TIGRFAM TIGR01579 MiaB-like-C: MiaB-like tRNA modifying enzyme 6 418 3.5E-142 T 28-03-2018 IPR006467 MiaB-like tRNA modifying enzyme GO:0016740 CIG75_RS19040 65a9724bbbd6fcf3d910f93f9914b83a 413 Pfam PF17288 Terminase RNAseH like domain 263 403 1.4E-7 T 28-03-2018 IPR035413 Phage terminase large subunit, C-terminal CIG75_RS19040 65a9724bbbd6fcf3d910f93f9914b83a 413 Pfam PF04466 Phage terminase large subunit 19 231 6.4E-46 T 28-03-2018 IPR035412 Phage terminase large subunit, N-terminal CIG75_RS19040 65a9724bbbd6fcf3d910f93f9914b83a 413 TIGRFAM TIGR01547 phage_term_2: phage terminase, large subunit, PBSX family 22 404 1.5E-44 T 28-03-2018 IPR006437 Bacteriophage terminase, large subunit GO:0006323 CIG75_RS16015 61e70db61a60029096716280e2b1f9bd 389 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 290 297 4.2E-5 T 28-03-2018 CIG75_RS16015 61e70db61a60029096716280e2b1f9bd 389 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 4.2E-5 T 28-03-2018 CIG75_RS16015 61e70db61a60029096716280e2b1f9bd 389 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 155 180 4.2E-5 T 28-03-2018 CIG75_RS16015 61e70db61a60029096716280e2b1f9bd 389 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 155 173 8.2E-9 T 28-03-2018 CIG75_RS16015 61e70db61a60029096716280e2b1f9bd 389 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 8.2E-9 T 28-03-2018 CIG75_RS16015 61e70db61a60029096716280e2b1f9bd 389 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 99 117 8.2E-9 T 28-03-2018 CIG75_RS16015 61e70db61a60029096716280e2b1f9bd 389 SUPERFAMILY SSF51905 162 331 1.01E-20 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS16015 61e70db61a60029096716280e2b1f9bd 389 SUPERFAMILY SSF51905 3 38 1.01E-20 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS16015 61e70db61a60029096716280e2b1f9bd 389 Gene3D G3DSA:3.50.50.60 2 126 8.0E-13 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS16015 61e70db61a60029096716280e2b1f9bd 389 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 318 4.5E-46 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS16015 61e70db61a60029096716280e2b1f9bd 389 SUPERFAMILY SSF51905 2 206 1.37E-28 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS16015 61e70db61a60029096716280e2b1f9bd 389 Gene3D G3DSA:3.50.50.60 127 328 1.3E-26 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS19805 64a9719d7a8f62474f3c2e6e0534e41a 78 Hamap MF_00422 Protein translocase subunit SecE [secE]. 19 74 12.016 T 28-03-2018 IPR022943 Preprotein translocase subunit SecE Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CIG75_RS19805 64a9719d7a8f62474f3c2e6e0534e41a 78 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 22 75 4.9E-18 T 28-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 CIG75_RS19805 64a9719d7a8f62474f3c2e6e0534e41a 78 Gene3D G3DSA:1.20.5.1030 21 72 8.8E-20 T 28-03-2018 CIG75_RS19805 64a9719d7a8f62474f3c2e6e0534e41a 78 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 22 75 2.4E-18 T 28-03-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CIG75_RS12065 acbc5f9ff44e0dacc83101a2aaf5f690 508 Pfam PF01514 Secretory protein of YscJ/FliF family 33 219 1.2E-54 T 28-03-2018 IPR006182 Secretory protein YscJ/FliF CIG75_RS12065 acbc5f9ff44e0dacc83101a2aaf5f690 508 Pfam PF08345 Flagellar M-ring protein C-terminal 258 414 1.6E-28 T 28-03-2018 IPR013556 Flagellar M-ring C-terminal CIG75_RS12065 acbc5f9ff44e0dacc83101a2aaf5f690 508 Gene3D G3DSA:3.30.70.1530 55 114 0.055 T 28-03-2018 CIG75_RS12065 acbc5f9ff44e0dacc83101a2aaf5f690 508 TIGRFAM TIGR00206 fliF: flagellar M-ring protein FliF 3 378 7.9E-77 T 28-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CIG75_RS12065 acbc5f9ff44e0dacc83101a2aaf5f690 508 PIRSF PIRSF004862 2 481 5.1E-103 T 28-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CIG75_RS12065 acbc5f9ff44e0dacc83101a2aaf5f690 508 PIRSF PIRSF004862 451 508 1.8E-4 T 28-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CIG75_RS12065 acbc5f9ff44e0dacc83101a2aaf5f690 508 PRINTS PR01009 Flagellar M-ring protein signature 271 289 3.0E-17 T 28-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CIG75_RS12065 acbc5f9ff44e0dacc83101a2aaf5f690 508 PRINTS PR01009 Flagellar M-ring protein signature 196 214 3.0E-17 T 28-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CIG75_RS12065 acbc5f9ff44e0dacc83101a2aaf5f690 508 PRINTS PR01009 Flagellar M-ring protein signature 120 138 3.0E-17 T 28-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CIG75_RS12065 acbc5f9ff44e0dacc83101a2aaf5f690 508 PRINTS PR01009 Flagellar M-ring protein signature 348 372 3.0E-17 T 28-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CIG75_RS12065 acbc5f9ff44e0dacc83101a2aaf5f690 508 PRINTS PR01009 Flagellar M-ring protein signature 152 166 3.0E-17 T 28-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CIG75_RS11895 e0aaddb65c63a0a270ac416ac3ef1641 233 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 6 17 - T 28-03-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 CIG75_RS11895 e0aaddb65c63a0a270ac416ac3ef1641 233 SUPERFAMILY SSF52313 6 227 1.96E-100 T 28-03-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain CIG75_RS11895 e0aaddb65c63a0a270ac416ac3ef1641 233 Gene3D G3DSA:3.40.50.10490 5 233 7.5E-104 T 28-03-2018 CIG75_RS11895 e0aaddb65c63a0a270ac416ac3ef1641 233 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 225 44.376 T 28-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS11895 e0aaddb65c63a0a270ac416ac3ef1641 233 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 4 226 1.1E-113 T 28-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS11895 e0aaddb65c63a0a270ac416ac3ef1641 233 PRINTS PR00395 Ribosomal protein S2 signature 196 210 2.4E-41 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS11895 e0aaddb65c63a0a270ac416ac3ef1641 233 PRINTS PR00395 Ribosomal protein S2 signature 175 186 2.4E-41 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS11895 e0aaddb65c63a0a270ac416ac3ef1641 233 PRINTS PR00395 Ribosomal protein S2 signature 37 46 2.4E-41 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS11895 e0aaddb65c63a0a270ac416ac3ef1641 233 PRINTS PR00395 Ribosomal protein S2 signature 6 24 2.4E-41 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS11895 e0aaddb65c63a0a270ac416ac3ef1641 233 PRINTS PR00395 Ribosomal protein S2 signature 87 104 2.4E-41 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS11895 e0aaddb65c63a0a270ac416ac3ef1641 233 PRINTS PR00395 Ribosomal protein S2 signature 158 175 2.4E-41 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS11895 e0aaddb65c63a0a270ac416ac3ef1641 233 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 158 182 - T 28-03-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 CIG75_RS11895 e0aaddb65c63a0a270ac416ac3ef1641 233 Pfam PF00318 Ribosomal protein S2 9 224 5.1E-101 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS07220 cc88982acff4fac4b3f6fee0e882a4c8 516 Pfam PF00171 Aldehyde dehydrogenase family 52 512 7.8E-154 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CIG75_RS07220 cc88982acff4fac4b3f6fee0e882a4c8 516 Gene3D G3DSA:3.40.309.10 306 491 1.8E-60 T 28-03-2018 CIG75_RS07220 cc88982acff4fac4b3f6fee0e882a4c8 516 Gene3D G3DSA:3.40.605.10 33 305 1.7E-81 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CIG75_RS07220 cc88982acff4fac4b3f6fee0e882a4c8 516 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 286 293 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CIG75_RS07220 cc88982acff4fac4b3f6fee0e882a4c8 516 TIGRFAM TIGR01237 D1pyr5carbox2: putative delta-1-pyrroline-5-carboxylate dehydrogenase 6 516 3.3E-239 T 28-03-2018 IPR005932 Putative 1-pyrroline-5-carboxylate dehydrogenase, Bacillales KEGG: 00250+1.2.1.88|KEGG: 00330+1.2.1.88|MetaCyc: PWY-6853 CIG75_RS07220 cc88982acff4fac4b3f6fee0e882a4c8 516 SUPERFAMILY SSF53720 5 515 1.57E-152 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CIG75_RS07220 cc88982acff4fac4b3f6fee0e882a4c8 516 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 314 325 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CIG75_RS01735 347d12b99adfb7958e61deb61ae7b7f0 285 TIGRFAM TIGR01859 fruc_bis_ald_: fructose-1,6-bisphosphate aldolase, class II 5 285 1.8E-116 T 28-03-2018 IPR011289 Fructose-1,6-bisphosphate aldolase, class 2 GO:0004332|GO:0006096|GO:0008270|GO:0030388 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 CIG75_RS01735 347d12b99adfb7958e61deb61ae7b7f0 285 Gene3D G3DSA:3.20.20.70 1 285 2.6E-106 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CIG75_RS01735 347d12b99adfb7958e61deb61ae7b7f0 285 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 131 142 - T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CIG75_RS01735 347d12b99adfb7958e61deb61ae7b7f0 285 Pfam PF01116 Fructose-bisphosphate aldolase class-II 6 284 1.1E-101 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CIG75_RS01735 347d12b99adfb7958e61deb61ae7b7f0 285 PIRSF PIRSF001359 1 285 2.0E-114 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CIG75_RS01735 347d12b99adfb7958e61deb61ae7b7f0 285 SUPERFAMILY SSF51569 3 285 4.98E-103 T 28-03-2018 CIG75_RS01735 347d12b99adfb7958e61deb61ae7b7f0 285 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 285 5.7E-102 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CIG75_RS02055 f79605114d6f6137ad67639d27c00e9a 278 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 10 30 - T 28-03-2018 IPR019776 Flagellar basal body rod protein, conserved site CIG75_RS02055 f79605114d6f6137ad67639d27c00e9a 278 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 196 275 4.3E-17 T 28-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain CIG75_RS02055 f79605114d6f6137ad67639d27c00e9a 278 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 2 145 9.9E-32 T 28-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G CIG75_RS02055 f79605114d6f6137ad67639d27c00e9a 278 Pfam PF00460 Flagella basal body rod protein 4 34 2.2E-11 T 28-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 CIG75_RS02055 f79605114d6f6137ad67639d27c00e9a 278 SUPERFAMILY SSF117143 93 237 4.45E-13 T 28-03-2018 CIG75_RS11480 3a4dc2a15ea1fd54dd950df0cac2283e 467 Gene3D G3DSA:3.30.470.20 290 426 4.7E-13 T 28-03-2018 CIG75_RS11480 3a4dc2a15ea1fd54dd950df0cac2283e 467 SUPERFAMILY SSF56059 194 423 1.81E-10 T 28-03-2018 CIG75_RS11480 3a4dc2a15ea1fd54dd950df0cac2283e 467 Gene3D G3DSA:3.30.1490.20 218 289 1.4E-9 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CIG75_RS11480 3a4dc2a15ea1fd54dd950df0cac2283e 467 Pfam PF14398 YheC/D like ATP-grasp 187 443 5.6E-78 T 28-03-2018 IPR026838 Endospore coat-associated protein YheC/D CIG75_RS20175 3d9f1323317839c9a28cee456c15af90 171 Pfam PF12389 Camelysin metallo-endopeptidase 1 83 2.2E-14 T 28-03-2018 IPR022121 Peptidase M73, camelysin CIG75_RS20175 3d9f1323317839c9a28cee456c15af90 171 Gene3D G3DSA:2.60.40.10 4 61 0.15 T 28-03-2018 IPR013783 Immunoglobulin-like fold CIG75_RS20175 3d9f1323317839c9a28cee456c15af90 171 Gene3D G3DSA:2.60.40.1710 62 164 1.0E-5 T 28-03-2018 CIG75_RS12125 e4206b77ff1b242f1ffa457b55906126 385 SUPERFAMILY SSF52210 238 385 2.22E-55 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CIG75_RS12125 e4206b77ff1b242f1ffa457b55906126 385 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 256 280 - T 28-03-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CIG75_RS12125 e4206b77ff1b242f1ffa457b55906126 385 Pfam PF08442 ATP-grasp domain 2 202 3.9E-80 T 28-03-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CIG75_RS12125 e4206b77ff1b242f1ffa457b55906126 385 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 385 44.474 T 28-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CIG75_RS12125 e4206b77ff1b242f1ffa457b55906126 385 Gene3D G3DSA:3.30.470.20 95 238 6.4E-55 T 28-03-2018 CIG75_RS12125 e4206b77ff1b242f1ffa457b55906126 385 PIRSF PIRSF001554 1 385 3.8E-153 T 28-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CIG75_RS12125 e4206b77ff1b242f1ffa457b55906126 385 Pfam PF00549 CoA-ligase 261 380 3.3E-26 T 28-03-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CIG75_RS12125 e4206b77ff1b242f1ffa457b55906126 385 Gene3D G3DSA:3.30.1490.20 21 94 4.0E-25 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CIG75_RS12125 e4206b77ff1b242f1ffa457b55906126 385 Gene3D G3DSA:3.40.50.261 239 384 6.1E-45 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CIG75_RS12125 e4206b77ff1b242f1ffa457b55906126 385 SUPERFAMILY SSF56059 1 237 1.71E-85 T 28-03-2018 CIG75_RS12125 e4206b77ff1b242f1ffa457b55906126 385 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 384 1.0E-160 T 28-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CIG75_RS17700 59515c22db64413f2fd7bf1fc9e2b1a3 209 Pfam PF04299 Putative FMN-binding domain 1 159 5.4E-54 T 28-03-2018 IPR007396 Transcriptional regulator PAI 2-type CIG75_RS17700 59515c22db64413f2fd7bf1fc9e2b1a3 209 Gene3D G3DSA:2.30.110.10 1 202 4.2E-63 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CIG75_RS17700 59515c22db64413f2fd7bf1fc9e2b1a3 209 SUPERFAMILY SSF50475 11 185 1.37E-37 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CIG75_RS17700 59515c22db64413f2fd7bf1fc9e2b1a3 209 PIRSF PIRSF010372 1 204 1.0E-66 T 28-03-2018 IPR007396 Transcriptional regulator PAI 2-type CIG75_RS11420 9295f34773190136247f86f935472941 182 SUPERFAMILY SSF50022 9 173 3.4E-24 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CIG75_RS11420 9295f34773190136247f86f935472941 182 Gene3D G3DSA:1.20.5.700 5 44 1.0E-10 T 28-03-2018 CIG75_RS11420 9295f34773190136247f86f935472941 182 PRINTS PR00162 Rieske 2Fe-2S subunit signature 102 113 8.1E-5 T 28-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 CIG75_RS11420 9295f34773190136247f86f935472941 182 PRINTS PR00162 Rieske 2Fe-2S subunit signature 134 146 8.1E-5 T 28-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 CIG75_RS11420 9295f34773190136247f86f935472941 182 Gene3D G3DSA:2.102.10.10 56 181 4.6E-18 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CIG75_RS11420 9295f34773190136247f86f935472941 182 Pfam PF00355 Rieske [2Fe-2S] domain 79 159 2.2E-12 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CIG75_RS04385 d20bda3403d9c548bc260a2f2eb63eee 571 SUPERFAMILY SSF55190 3 109 4.84E-21 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CIG75_RS04385 d20bda3403d9c548bc260a2f2eb63eee 571 Pfam PF00750 tRNA synthetases class I (R) 98 440 7.9E-99 T 28-03-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 CIG75_RS04385 d20bda3403d9c548bc260a2f2eb63eee 571 SUPERFAMILY SSF52374 114 448 1.39E-102 T 28-03-2018 CIG75_RS04385 d20bda3403d9c548bc260a2f2eb63eee 571 Gene3D G3DSA:3.40.50.620 111 434 3.5E-65 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CIG75_RS04385 d20bda3403d9c548bc260a2f2eb63eee 571 SMART SM00836 454 571 3.8E-40 T 28-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 CIG75_RS04385 d20bda3403d9c548bc260a2f2eb63eee 571 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 4 88 4.0E-14 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CIG75_RS04385 d20bda3403d9c548bc260a2f2eb63eee 571 PRINTS PR01038 Arginyl-tRNA synthetase signature 118 133 5.6E-20 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CIG75_RS04385 d20bda3403d9c548bc260a2f2eb63eee 571 PRINTS PR01038 Arginyl-tRNA synthetase signature 133 149 5.6E-20 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CIG75_RS04385 d20bda3403d9c548bc260a2f2eb63eee 571 PRINTS PR01038 Arginyl-tRNA synthetase signature 157 170 5.6E-20 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CIG75_RS04385 d20bda3403d9c548bc260a2f2eb63eee 571 PRINTS PR01038 Arginyl-tRNA synthetase signature 301 322 5.6E-20 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CIG75_RS04385 d20bda3403d9c548bc260a2f2eb63eee 571 Hamap MF_00123 Arginine--tRNA ligase [argS]. 5 571 25.757 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CIG75_RS04385 d20bda3403d9c548bc260a2f2eb63eee 571 Gene3D G3DSA:3.30.1360.70 2 109 1.0E-26 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CIG75_RS04385 d20bda3403d9c548bc260a2f2eb63eee 571 SUPERFAMILY SSF47323 450 571 2.88E-33 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CIG75_RS04385 d20bda3403d9c548bc260a2f2eb63eee 571 Gene3D G3DSA:1.10.730.10 435 571 1.4E-43 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CIG75_RS04385 d20bda3403d9c548bc260a2f2eb63eee 571 SMART SM01016 5 88 1.2E-16 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CIG75_RS04385 d20bda3403d9c548bc260a2f2eb63eee 571 Pfam PF05746 DALR anticodon binding domain 454 571 1.4E-32 T 28-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 CIG75_RS04385 d20bda3403d9c548bc260a2f2eb63eee 571 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 5 571 3.9E-152 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CIG75_RS13685 d23aadc24e2ace00e00de8a517c1dea1 427 Gene3D G3DSA:1.25.40.10 281 423 3.4E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS13685 d23aadc24e2ace00e00de8a517c1dea1 427 SMART SM00530 7 61 1.2E-15 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS13685 d23aadc24e2ace00e00de8a517c1dea1 427 Gene3D G3DSA:1.25.40.10 162 220 2.1E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS13685 d23aadc24e2ace00e00de8a517c1dea1 427 SMART SM00028 228 261 2.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS13685 d23aadc24e2ace00e00de8a517c1dea1 427 SMART SM00028 188 221 35.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS13685 d23aadc24e2ace00e00de8a517c1dea1 427 SMART SM00028 308 341 56.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS13685 d23aadc24e2ace00e00de8a517c1dea1 427 SMART SM00028 268 301 34.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS13685 d23aadc24e2ace00e00de8a517c1dea1 427 SMART SM00028 146 179 24.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS13685 d23aadc24e2ace00e00de8a517c1dea1 427 SUPERFAMILY SSF48452 271 418 2.66E-15 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS13685 d23aadc24e2ace00e00de8a517c1dea1 427 Pfam PF13424 Tetratricopeptide repeat 273 339 1.1E-8 T 28-03-2018 CIG75_RS13685 d23aadc24e2ace00e00de8a517c1dea1 427 Pfam PF13424 Tetratricopeptide repeat 188 259 2.4E-7 T 28-03-2018 CIG75_RS13685 d23aadc24e2ace00e00de8a517c1dea1 427 SUPERFAMILY SSF48452 75 262 2.66E-19 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS13685 d23aadc24e2ace00e00de8a517c1dea1 427 Pfam PF01381 Helix-turn-helix 8 61 4.8E-14 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS13685 d23aadc24e2ace00e00de8a517c1dea1 427 SUPERFAMILY SSF47413 2 67 1.21E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CIG75_RS13685 d23aadc24e2ace00e00de8a517c1dea1 427 Gene3D G3DSA:1.25.40.10 86 161 1.2E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS13685 d23aadc24e2ace00e00de8a517c1dea1 427 Gene3D G3DSA:1.10.3100.10 1 85 5.8E-20 T 28-03-2018 IPR027910 YdiL-like domain CIG75_RS13685 d23aadc24e2ace00e00de8a517c1dea1 427 Gene3D G3DSA:1.10.150.200 221 280 3.7E-8 T 28-03-2018 CIG75_RS15580 8305da8faa0a370f4e0cad7c95bfe74f 157 Gene3D G3DSA:1.10.287.180 5 78 1.5E-29 T 28-03-2018 CIG75_RS15580 8305da8faa0a370f4e0cad7c95bfe74f 157 Pfam PF03449 Transcription elongation factor, N-terminal 7 76 5.5E-29 T 28-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 CIG75_RS15580 8305da8faa0a370f4e0cad7c95bfe74f 157 SUPERFAMILY SSF46557 6 79 1.23E-25 T 28-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 CIG75_RS15580 8305da8faa0a370f4e0cad7c95bfe74f 157 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 8 156 4.2E-53 T 28-03-2018 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 CIG75_RS15580 8305da8faa0a370f4e0cad7c95bfe74f 157 SUPERFAMILY SSF54534 83 156 2.88E-20 T 28-03-2018 CIG75_RS15580 8305da8faa0a370f4e0cad7c95bfe74f 157 Hamap MF_00105 Transcription elongation factor GreA [greA]. 4 157 30.265 T 28-03-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 CIG75_RS15580 8305da8faa0a370f4e0cad7c95bfe74f 157 PIRSF PIRSF006092 1 157 7.7E-50 T 28-03-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 CIG75_RS15580 8305da8faa0a370f4e0cad7c95bfe74f 157 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 122 138 - T 28-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 CIG75_RS15580 8305da8faa0a370f4e0cad7c95bfe74f 157 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 19 50 - T 28-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 CIG75_RS15580 8305da8faa0a370f4e0cad7c95bfe74f 157 Gene3D G3DSA:3.10.50.30 81 153 2.1E-25 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CIG75_RS15580 8305da8faa0a370f4e0cad7c95bfe74f 157 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 85 156 1.6E-25 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CIG75_RS16820 d8eae6fc0619a05857575c192e62b29b 225 Gene3D G3DSA:1.10.10.60 6 103 1.3E-15 T 28-03-2018 CIG75_RS16820 d8eae6fc0619a05857575c192e62b29b 225 SUPERFAMILY SSF46689 29 91 1.6E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CIG75_RS16820 d8eae6fc0619a05857575c192e62b29b 225 Gene3D G3DSA:1.10.357.10 104 225 5.1E-18 T 28-03-2018 CIG75_RS16820 d8eae6fc0619a05857575c192e62b29b 225 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 46 2.6E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CIG75_RS16820 d8eae6fc0619a05857575c192e62b29b 225 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 54 77 2.6E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CIG75_RS16820 d8eae6fc0619a05857575c192e62b29b 225 SUPERFAMILY SSF48498 108 223 4.45E-10 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CIG75_RS16820 d8eae6fc0619a05857575c192e62b29b 225 Pfam PF00440 Bacterial regulatory proteins, tetR family 33 76 6.3E-17 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CIG75_RS10195 ab84c81157615b4ffe017a677b9a2dfc 317 SUPERFAMILY SSF53067 115 308 1.04E-52 T 28-03-2018 CIG75_RS10195 ab84c81157615b4ffe017a677b9a2dfc 317 Gene3D G3DSA:3.30.420.40 115 278 7.0E-44 T 28-03-2018 CIG75_RS10195 ab84c81157615b4ffe017a677b9a2dfc 317 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 5 297 2.5E-39 T 28-03-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 CIG75_RS10195 ab84c81157615b4ffe017a677b9a2dfc 317 Gene3D G3DSA:3.30.420.40 4 102 1.0E-18 T 28-03-2018 CIG75_RS10195 ab84c81157615b4ffe017a677b9a2dfc 317 SUPERFAMILY SSF53067 1 110 2.96E-15 T 28-03-2018 CIG75_RS10470 884ccf5711da9566eb5e249e18422dd5 1526 Pfam PF00698 Acyl transferase domain 534 848 1.3E-44 T 28-03-2018 IPR014043 Acyl transferase CIG75_RS10470 884ccf5711da9566eb5e249e18422dd5 1526 SUPERFAMILY SSF55048 685 740 6.93E-9 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CIG75_RS10470 884ccf5711da9566eb5e249e18422dd5 1526 Gene3D G3DSA:3.40.50.720 948 1069 0.14 T 28-03-2018 CIG75_RS10470 884ccf5711da9566eb5e249e18422dd5 1526 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 535 852 2.7E-100 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CIG75_RS10470 884ccf5711da9566eb5e249e18422dd5 1526 SMART SM00823 Phosphopantetheine attachment site 1442 1511 8.8E-7 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS10470 884ccf5711da9566eb5e249e18422dd5 1526 Pfam PF08659 KR domain 1170 1367 4.0E-37 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS10470 884ccf5711da9566eb5e249e18422dd5 1526 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1170 1376 2.8E-22 T 28-03-2018 CIG75_RS10470 884ccf5711da9566eb5e249e18422dd5 1526 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1466 1481 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS10470 884ccf5711da9566eb5e249e18422dd5 1526 Gene3D G3DSA:3.30.70.250 696 738 2.3E-15 T 28-03-2018 CIG75_RS10470 884ccf5711da9566eb5e249e18422dd5 1526 Pfam PF00550 Phosphopantetheine attachment site 1444 1504 6.4E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10470 884ccf5711da9566eb5e249e18422dd5 1526 Gene3D G3DSA:3.40.50.720 1112 1427 3.6E-31 T 28-03-2018 CIG75_RS10470 884ccf5711da9566eb5e249e18422dd5 1526 Gene3D G3DSA:3.40.366.10 739 862 6.5E-25 T 28-03-2018 CIG75_RS10470 884ccf5711da9566eb5e249e18422dd5 1526 SMART SM00825 Beta-ketoacyl synthase 11 438 2.6E-178 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CIG75_RS10470 884ccf5711da9566eb5e249e18422dd5 1526 SUPERFAMILY SSF51735 1167 1396 2.37E-26 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS10470 884ccf5711da9566eb5e249e18422dd5 1526 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 267 386 1.6E-43 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CIG75_RS10470 884ccf5711da9566eb5e249e18422dd5 1526 Gene3D G3DSA:3.40.47.10 275 440 4.3E-58 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS10470 884ccf5711da9566eb5e249e18422dd5 1526 Gene3D G3DSA:3.40.47.10 1 271 9.1E-66 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS10470 884ccf5711da9566eb5e249e18422dd5 1526 SUPERFAMILY SSF52151 532 585 2.62E-65 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CIG75_RS10470 884ccf5711da9566eb5e249e18422dd5 1526 SUPERFAMILY SSF52151 614 687 2.62E-65 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CIG75_RS10470 884ccf5711da9566eb5e249e18422dd5 1526 SUPERFAMILY SSF52151 747 844 2.62E-65 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CIG75_RS10470 884ccf5711da9566eb5e249e18422dd5 1526 SUPERFAMILY SSF53901 413 433 4.2E-86 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS10470 884ccf5711da9566eb5e249e18422dd5 1526 SUPERFAMILY SSF53901 9 127 4.2E-86 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS10470 884ccf5711da9566eb5e249e18422dd5 1526 SUPERFAMILY SSF53901 155 381 4.2E-86 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS10470 884ccf5711da9566eb5e249e18422dd5 1526 SUPERFAMILY SSF51735 926 1156 1.42E-14 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS10470 884ccf5711da9566eb5e249e18422dd5 1526 SUPERFAMILY SSF47336 1434 1507 3.93E-18 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10470 884ccf5711da9566eb5e249e18422dd5 1526 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 11 259 1.7E-67 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CIG75_RS10470 884ccf5711da9566eb5e249e18422dd5 1526 Gene3D G3DSA:3.40.366.10 531 695 1.8E-41 T 28-03-2018 CIG75_RS10470 884ccf5711da9566eb5e249e18422dd5 1526 Gene3D G3DSA:1.10.1200.10 1428 1516 3.6E-20 T 28-03-2018 CIG75_RS10470 884ccf5711da9566eb5e249e18422dd5 1526 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 388 491 3.2E-18 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS01265 1f0331bf69da1681e03eec033a60b004 226 TIGRFAM TIGR03717 R_switched_YjbE: integral membrane protein, YjbE family 11 182 2.7E-69 T 28-03-2018 IPR022301 Integral membrane protein YjbE CIG75_RS01265 1f0331bf69da1681e03eec033a60b004 226 Pfam PF03741 Integral membrane protein TerC family 14 182 1.1E-45 T 28-03-2018 IPR005496 Integral membrane protein TerC GO:0016021 CIG75_RS13270 a03f1175e83bdabe95f3af1ba5951977 383 Gene3D G3DSA:3.50.50.60 14 328 1.0E-38 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS13270 a03f1175e83bdabe95f3af1ba5951977 383 SUPERFAMILY SSF51905 19 184 9.04E-42 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS13270 a03f1175e83bdabe95f3af1ba5951977 383 SUPERFAMILY SSF51905 288 372 9.04E-42 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS13270 a03f1175e83bdabe95f3af1ba5951977 383 Pfam PF01494 FAD binding domain 22 333 8.0E-15 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CIG75_RS13270 a03f1175e83bdabe95f3af1ba5951977 383 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 292 307 1.6E-6 T 28-03-2018 CIG75_RS13270 a03f1175e83bdabe95f3af1ba5951977 383 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 163 178 1.6E-6 T 28-03-2018 CIG75_RS13270 a03f1175e83bdabe95f3af1ba5951977 383 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 22 44 1.6E-6 T 28-03-2018 CIG75_RS17100 4145ae877a41908e5b755a76f71c3013 271 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 159 261 5.2E-18 T 28-03-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 CIG75_RS17100 4145ae877a41908e5b755a76f71c3013 271 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 1 263 16.263 T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CIG75_RS17100 4145ae877a41908e5b755a76f71c3013 271 SUPERFAMILY SSF51735 2 157 5.72E-22 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS17100 4145ae877a41908e5b755a76f71c3013 271 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 2 95 6.9E-18 T 28-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal CIG75_RS17100 4145ae877a41908e5b755a76f71c3013 271 SUPERFAMILY SSF48179 158 263 1.34E-18 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CIG75_RS17100 4145ae877a41908e5b755a76f71c3013 271 Gene3D G3DSA:1.10.3730.10 157 267 3.9E-21 T 28-03-2018 CIG75_RS17100 4145ae877a41908e5b755a76f71c3013 271 PIRSF PIRSF000193 1 266 4.6E-65 T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CIG75_RS17100 4145ae877a41908e5b755a76f71c3013 271 Gene3D G3DSA:3.40.50.720 1 156 1.0E-24 T 28-03-2018 CIG75_RS00125 df8fc8c241f6bdfa1c8332fd8e9e857e 226 Gene3D G3DSA:3.40.50.300 13 223 8.5E-42 T 28-03-2018 CIG75_RS00125 df8fc8c241f6bdfa1c8332fd8e9e857e 226 SUPERFAMILY SSF52540 17 217 7.27E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS00125 df8fc8c241f6bdfa1c8332fd8e9e857e 226 PIRSF PIRSF000705 3 226 2.9E-63 T 28-03-2018 IPR002624 Deoxynucleoside kinase GO:0005524|GO:0006139|GO:0019206 CIG75_RS00125 df8fc8c241f6bdfa1c8332fd8e9e857e 226 Pfam PF01712 Deoxynucleoside kinase 18 215 1.0E-61 T 28-03-2018 IPR031314 Deoxynucleoside kinase domain CIG75_RS07180 b00d5eb9c5b05133d9dc2310e21a73c4 425 Gene3D G3DSA:1.20.1250.20 7 314 4.1E-5 T 28-03-2018 CIG75_RS07180 b00d5eb9c5b05133d9dc2310e21a73c4 425 Pfam PF13559 Domain of unknown function (DUF4129) 350 407 3.7E-9 T 28-03-2018 IPR025403 Domain of unknown function DUF4129 CIG75_RS20295 8bce5696d9034d6b71478e451c9b2b05 461 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 316 351 4.0E-6 T 28-03-2018 IPR001451 Hexapeptide repeat CIG75_RS20295 8bce5696d9034d6b71478e451c9b2b05 461 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 284 312 7.4E-5 T 28-03-2018 IPR001451 Hexapeptide repeat CIG75_RS20295 8bce5696d9034d6b71478e451c9b2b05 461 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 6 451 2.7E-170 T 28-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 CIG75_RS20295 8bce5696d9034d6b71478e451c9b2b05 461 Gene3D G3DSA:2.160.10.10 342 455 1.4E-23 T 28-03-2018 CIG75_RS20295 8bce5696d9034d6b71478e451c9b2b05 461 Gene3D G3DSA:2.160.10.10 240 341 2.6E-28 T 28-03-2018 CIG75_RS20295 8bce5696d9034d6b71478e451c9b2b05 461 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 325 353 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CIG75_RS20295 8bce5696d9034d6b71478e451c9b2b05 461 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 394 427 1.1E-6 T 28-03-2018 IPR001451 Hexapeptide repeat CIG75_RS20295 8bce5696d9034d6b71478e451c9b2b05 461 SUPERFAMILY SSF53448 5 306 7.89E-64 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CIG75_RS20295 8bce5696d9034d6b71478e451c9b2b05 461 SUPERFAMILY SSF51161 248 451 4.81E-48 T 28-03-2018 IPR011004 Trimeric LpxA-like CIG75_RS20295 8bce5696d9034d6b71478e451c9b2b05 461 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 402 430 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CIG75_RS20295 8bce5696d9034d6b71478e451c9b2b05 461 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 3 451 40.283 T 28-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 CIG75_RS20295 8bce5696d9034d6b71478e451c9b2b05 461 Pfam PF12804 MobA-like NTP transferase domain 6 131 1.0E-21 T 28-03-2018 IPR025877 MobA-like NTP transferase CIG75_RS20295 8bce5696d9034d6b71478e451c9b2b05 461 Gene3D G3DSA:3.90.550.10 3 239 5.6E-59 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CIG75_RS04070 ac3f3d2cd4eb46465fd0f49356ae52bc 608 SUPERFAMILY SSF55874 471 595 1.83E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS04070 ac3f3d2cd4eb46465fd0f49356ae52bc 608 Pfam PF07730 Histidine kinase 396 459 1.4E-14 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CIG75_RS04070 ac3f3d2cd4eb46465fd0f49356ae52bc 608 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 503 596 1.7E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS04070 ac3f3d2cd4eb46465fd0f49356ae52bc 608 Pfam PF13185 GAF domain 247 379 6.0E-14 T 28-03-2018 IPR003018 GAF domain GO:0005515 CIG75_RS04070 ac3f3d2cd4eb46465fd0f49356ae52bc 608 Gene3D G3DSA:3.30.450.40 223 452 2.7E-28 T 28-03-2018 IPR029016 GAF domain-like CIG75_RS04070 ac3f3d2cd4eb46465fd0f49356ae52bc 608 SMART SM00065 248 389 1.9E-13 T 28-03-2018 IPR003018 GAF domain GO:0005515 CIG75_RS04070 ac3f3d2cd4eb46465fd0f49356ae52bc 608 Gene3D G3DSA:3.30.565.10 461 603 2.8E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS04070 ac3f3d2cd4eb46465fd0f49356ae52bc 608 SMART SM00387 499 597 1.9E-6 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS04070 ac3f3d2cd4eb46465fd0f49356ae52bc 608 SUPERFAMILY SSF55781 221 381 1.37E-25 T 28-03-2018 IPR029016 GAF domain-like CIG75_RS15130 0a338c439f364b21241b530a93247116 430 SMART SM00854 6 311 3.9E-54 T 28-03-2018 IPR019079 Capsule synthesis protein, CapA CIG75_RS15130 0a338c439f364b21241b530a93247116 430 Pfam PF09587 Bacterial capsule synthesis protein PGA_cap 7 310 1.0E-63 T 28-03-2018 IPR019079 Capsule synthesis protein, CapA CIG75_RS15130 0a338c439f364b21241b530a93247116 430 Gene3D G3DSA:3.60.21.10 3 402 1.2E-49 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CIG75_RS15130 0a338c439f364b21241b530a93247116 430 SUPERFAMILY SSF56300 221 322 1.08E-28 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CIG75_RS15130 0a338c439f364b21241b530a93247116 430 SUPERFAMILY SSF56300 5 139 1.08E-28 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CIG75_RS07545 3eaaa25f0af02fcf8f68e21eaa9ae3a4 348 Pfam PF01699 Sodium/calcium exchanger protein 204 341 5.8E-18 T 28-03-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 CIG75_RS07545 3eaaa25f0af02fcf8f68e21eaa9ae3a4 348 Pfam PF01699 Sodium/calcium exchanger protein 27 178 5.4E-19 T 28-03-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 CIG75_RS07545 3eaaa25f0af02fcf8f68e21eaa9ae3a4 348 TIGRFAM TIGR00846 caca2: calcium/proton exchanger 3 345 9.8E-112 T 28-03-2018 IPR004713 Calcium/proton exchanger GO:0006812|GO:0008324|GO:0016021|GO:0055085 CIG75_RS07545 3eaaa25f0af02fcf8f68e21eaa9ae3a4 348 TIGRFAM TIGR00378 cax: calcium/proton exchanger 9 346 1.3E-130 T 28-03-2018 IPR004798 Calcium/proton exchanger CAX GO:0006816|GO:0015369 CIG75_RS10815 b8471a5b2c9d04f3bc530df366097868 184 Pfam PF00011 Hsp20/alpha crystallin family 78 175 9.1E-13 T 28-03-2018 IPR002068 Alpha crystallin/Hsp20 domain CIG75_RS10815 b8471a5b2c9d04f3bc530df366097868 184 Gene3D G3DSA:2.60.40.790 10 183 1.9E-22 T 28-03-2018 IPR008978 HSP20-like chaperone CIG75_RS10815 b8471a5b2c9d04f3bc530df366097868 184 SUPERFAMILY SSF49764 56 175 1.57E-22 T 28-03-2018 IPR008978 HSP20-like chaperone CIG75_RS18650 67264199740ea1dec7ec1ccc1047ec4f 515 Gene3D G3DSA:3.40.50.1380 1 191 8.4E-68 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CIG75_RS18650 67264199740ea1dec7ec1ccc1047ec4f 515 Gene3D G3DSA:3.40.140.20 214 358 1.7E-55 T 28-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CIG75_RS18650 67264199740ea1dec7ec1ccc1047ec4f 515 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 2 515 5.4E-217 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CIG75_RS18650 67264199740ea1dec7ec1ccc1047ec4f 515 PIRSF PIRSF000414 1 515 4.0E-209 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CIG75_RS18650 67264199740ea1dec7ec1ccc1047ec4f 515 Pfam PF02142 MGS-like domain 13 127 8.7E-25 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CIG75_RS18650 67264199740ea1dec7ec1ccc1047ec4f 515 Pfam PF01808 AICARFT/IMPCHase bienzyme 133 449 3.4E-118 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CIG75_RS18650 67264199740ea1dec7ec1ccc1047ec4f 515 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 1 515 43.798 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CIG75_RS18650 67264199740ea1dec7ec1ccc1047ec4f 515 SMART SM00851 13 128 8.6E-50 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CIG75_RS18650 67264199740ea1dec7ec1ccc1047ec4f 515 SMART SM00798 133 450 3.8E-194 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CIG75_RS18650 67264199740ea1dec7ec1ccc1047ec4f 515 SUPERFAMILY SSF53927 205 515 4.01E-125 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CIG75_RS18650 67264199740ea1dec7ec1ccc1047ec4f 515 SUPERFAMILY SSF52335 2 192 9.52E-67 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CIG75_RS18650 67264199740ea1dec7ec1ccc1047ec4f 515 Gene3D G3DSA:3.40.140.20 365 505 1.9E-46 T 28-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CIG75_RS09495 90d62885edfd4bfe1bf92769a5f129b5 395 SMART SM00028 124 157 0.0014 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS09495 90d62885edfd4bfe1bf92769a5f129b5 395 SMART SM00028 246 279 140.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS09495 90d62885edfd4bfe1bf92769a5f129b5 395 SUPERFAMILY SSF47413 15 78 1.42E-6 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CIG75_RS09495 90d62885edfd4bfe1bf92769a5f129b5 395 SUPERFAMILY SSF48452 125 329 2.33E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS09495 90d62885edfd4bfe1bf92769a5f129b5 395 SMART SM00530 20 77 0.0018 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS09495 90d62885edfd4bfe1bf92769a5f129b5 395 Gene3D G3DSA:1.10.260.40 4 89 1.8E-9 T 28-03-2018 CIG75_RS09495 90d62885edfd4bfe1bf92769a5f129b5 395 Gene3D G3DSA:1.25.40.10 90 389 7.6E-20 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS20290 90a7798868396c9a48154bc484e93efb 317 SMART SM01400 9 125 2.6E-78 T 28-03-2018 CIG75_RS20290 90a7798868396c9a48154bc484e93efb 317 SUPERFAMILY SSF53271 74 310 1.1E-63 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CIG75_RS20290 90a7798868396c9a48154bc484e93efb 317 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 10 317 7.2E-123 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CIG75_RS20290 90a7798868396c9a48154bc484e93efb 317 Pfam PF14572 Phosphoribosyl synthetase-associated domain 207 317 6.7E-25 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CIG75_RS20290 90a7798868396c9a48154bc484e93efb 317 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 9 317 48.226 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CIG75_RS20290 90a7798868396c9a48154bc484e93efb 317 Gene3D G3DSA:3.40.50.2020 160 294 8.4E-40 T 28-03-2018 CIG75_RS20290 90a7798868396c9a48154bc484e93efb 317 Gene3D G3DSA:3.40.50.2020 6 159 9.6E-68 T 28-03-2018 CIG75_RS20290 90a7798868396c9a48154bc484e93efb 317 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 133 148 - T 28-03-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 CIG75_RS20290 90a7798868396c9a48154bc484e93efb 317 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 9 125 2.2E-49 T 28-03-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CIG75_RS00195 a55564b1ddfdcef66905ee0aa372adc5 642 SUPERFAMILY SSF54211 230 401 4.55E-61 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CIG75_RS00195 a55564b1ddfdcef66905ee0aa372adc5 642 PRINTS PR01159 DNA gyrase subunit B signature 370 384 4.7E-74 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CIG75_RS00195 a55564b1ddfdcef66905ee0aa372adc5 642 PRINTS PR01159 DNA gyrase subunit B signature 612 628 4.7E-74 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CIG75_RS00195 a55564b1ddfdcef66905ee0aa372adc5 642 PRINTS PR01159 DNA gyrase subunit B signature 203 216 4.7E-74 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CIG75_RS00195 a55564b1ddfdcef66905ee0aa372adc5 642 PRINTS PR01159 DNA gyrase subunit B signature 322 338 4.7E-74 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CIG75_RS00195 a55564b1ddfdcef66905ee0aa372adc5 642 PRINTS PR01159 DNA gyrase subunit B signature 10 20 4.7E-74 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CIG75_RS00195 a55564b1ddfdcef66905ee0aa372adc5 642 PRINTS PR01159 DNA gyrase subunit B signature 188 203 4.7E-74 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CIG75_RS00195 a55564b1ddfdcef66905ee0aa372adc5 642 PRINTS PR01159 DNA gyrase subunit B signature 229 251 4.7E-74 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CIG75_RS00195 a55564b1ddfdcef66905ee0aa372adc5 642 PRINTS PR01159 DNA gyrase subunit B signature 596 608 4.7E-74 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CIG75_RS00195 a55564b1ddfdcef66905ee0aa372adc5 642 PRINTS PR01159 DNA gyrase subunit B signature 384 404 4.7E-74 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CIG75_RS00195 a55564b1ddfdcef66905ee0aa372adc5 642 PRINTS PR01159 DNA gyrase subunit B signature 480 489 4.7E-74 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CIG75_RS00195 a55564b1ddfdcef66905ee0aa372adc5 642 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 571 632 1.8E-30 T 28-03-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 CIG75_RS00195 a55564b1ddfdcef66905ee0aa372adc5 642 Pfam PF00204 DNA gyrase B 230 400 1.7E-65 T 28-03-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CIG75_RS00195 a55564b1ddfdcef66905ee0aa372adc5 642 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 37 181 3.1E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS00195 a55564b1ddfdcef66905ee0aa372adc5 642 ProSitePatterns PS00177 DNA topoisomerase II signature. 432 440 - T 28-03-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CIG75_RS00195 a55564b1ddfdcef66905ee0aa372adc5 642 Gene3D G3DSA:3.30.230.10 229 402 1.3E-64 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CIG75_RS00195 a55564b1ddfdcef66905ee0aa372adc5 642 Pfam PF01751 Toprim domain 429 540 2.3E-18 T 28-03-2018 IPR006171 TOPRIM domain CIG75_RS00195 a55564b1ddfdcef66905ee0aa372adc5 642 SMART SM00433 39 636 0.0 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CIG75_RS00195 a55564b1ddfdcef66905ee0aa372adc5 642 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 7 642 92.644 T 28-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CIG75_RS00195 a55564b1ddfdcef66905ee0aa372adc5 642 Gene3D G3DSA:3.30.565.10 22 228 1.2E-72 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS00195 a55564b1ddfdcef66905ee0aa372adc5 642 PRINTS PR00418 DNA topoisomerase II family signature 514 531 7.9E-73 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CIG75_RS00195 a55564b1ddfdcef66905ee0aa372adc5 642 PRINTS PR00418 DNA topoisomerase II family signature 278 291 7.9E-73 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CIG75_RS00195 a55564b1ddfdcef66905ee0aa372adc5 642 PRINTS PR00418 DNA topoisomerase II family signature 496 512 7.9E-73 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CIG75_RS00195 a55564b1ddfdcef66905ee0aa372adc5 642 PRINTS PR00418 DNA topoisomerase II family signature 39 54 7.9E-73 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CIG75_RS00195 a55564b1ddfdcef66905ee0aa372adc5 642 PRINTS PR00418 DNA topoisomerase II family signature 74 87 7.9E-73 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CIG75_RS00195 a55564b1ddfdcef66905ee0aa372adc5 642 PRINTS PR00418 DNA topoisomerase II family signature 117 131 7.9E-73 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CIG75_RS00195 a55564b1ddfdcef66905ee0aa372adc5 642 PRINTS PR00418 DNA topoisomerase II family signature 430 444 7.9E-73 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CIG75_RS00195 a55564b1ddfdcef66905ee0aa372adc5 642 PRINTS PR00418 DNA topoisomerase II family signature 534 546 7.9E-73 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CIG75_RS00195 a55564b1ddfdcef66905ee0aa372adc5 642 PRINTS PR00418 DNA topoisomerase II family signature 575 591 7.9E-73 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CIG75_RS00195 a55564b1ddfdcef66905ee0aa372adc5 642 SUPERFAMILY SSF56719 404 635 3.14E-92 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CIG75_RS00195 a55564b1ddfdcef66905ee0aa372adc5 642 SMART SM00387 35 182 1.6E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS00195 a55564b1ddfdcef66905ee0aa372adc5 642 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 10 641 0.0 T 28-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CIG75_RS00195 a55564b1ddfdcef66905ee0aa372adc5 642 SUPERFAMILY SSF55874 10 221 1.83E-69 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS00195 a55564b1ddfdcef66905ee0aa372adc5 642 Gene3D G3DSA:3.40.50.670 409 640 8.3E-107 T 28-03-2018 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CIG75_RS03775 5918bcddf7c4557320d3a0ad81ff8841 259 Pfam PF13739 Domain of unknown function (DUF4163) 80 156 2.0E-10 T 28-03-2018 IPR025303 Deacetylase PdaC CIG75_RS03775 5918bcddf7c4557320d3a0ad81ff8841 259 Gene3D G3DSA:3.90.640.20 172 258 7.2E-16 T 28-03-2018 IPR021729 Domain of unknown function DUF3298 CIG75_RS03775 5918bcddf7c4557320d3a0ad81ff8841 259 Gene3D G3DSA:3.30.565.40 66 170 1.1E-14 T 28-03-2018 CIG75_RS03775 5918bcddf7c4557320d3a0ad81ff8841 259 Pfam PF11738 Protein of unknown function (DUF3298) 174 246 7.5E-10 T 28-03-2018 IPR021729 Domain of unknown function DUF3298 CIG75_RS16385 7c5d4c6d31a9263048ead0f772782427 309 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 133 147 - T 28-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 CIG75_RS16385 7c5d4c6d31a9263048ead0f772782427 309 Gene3D G3DSA:3.30.2350.10 81 303 1.1E-67 T 28-03-2018 CIG75_RS16385 7c5d4c6d31a9263048ead0f772782427 309 Gene3D G3DSA:3.10.290.10 3 73 1.3E-6 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CIG75_RS16385 7c5d4c6d31a9263048ead0f772782427 309 Pfam PF00849 RNA pseudouridylate synthase 90 241 1.0E-34 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CIG75_RS16385 7c5d4c6d31a9263048ead0f772782427 309 SUPERFAMILY SSF55120 76 300 4.86E-69 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CIG75_RS16385 7c5d4c6d31a9263048ead0f772782427 309 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 15 299 1.5E-83 T 28-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 CIG75_RS07585 cf21b60b52b9310fca507baa87e75623 401 TIGRFAM TIGR01127 ilvA_1Cterm: threonine ammonia-lyase 21 398 1.7E-160 T 28-03-2018 IPR005789 Threonine dehydratase, catabolic GO:0004794|GO:0006567 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 CIG75_RS07585 cf21b60b52b9310fca507baa87e75623 401 SUPERFAMILY SSF53686 5 314 1.44E-104 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CIG75_RS07585 cf21b60b52b9310fca507baa87e75623 401 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 42 55 - T 28-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 CIG75_RS07585 cf21b60b52b9310fca507baa87e75623 401 Gene3D G3DSA:3.30.70.260 325 399 1.8E-10 T 28-03-2018 CIG75_RS07585 cf21b60b52b9310fca507baa87e75623 401 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 16 303 8.9E-85 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CIG75_RS07585 cf21b60b52b9310fca507baa87e75623 401 Gene3D G3DSA:3.40.50.1100 26 137 2.1E-33 T 28-03-2018 CIG75_RS07585 cf21b60b52b9310fca507baa87e75623 401 Pfam PF01842 ACT domain 328 393 2.6E-9 T 28-03-2018 IPR002912 ACT domain CIG75_RS07585 cf21b60b52b9310fca507baa87e75623 401 Gene3D G3DSA:3.40.50.1100 138 309 6.1E-51 T 28-03-2018 CIG75_RS07585 cf21b60b52b9310fca507baa87e75623 401 SUPERFAMILY SSF55021 327 395 3.44E-9 T 28-03-2018 CIG75_RS04355 61ad7670c838dcd1be9e57ee554fe465 293 Gene3D G3DSA:1.20.1510.10 11 206 2.4E-45 T 28-03-2018 CIG75_RS04355 61ad7670c838dcd1be9e57ee554fe465 293 SUPERFAMILY SSF160240 211 290 4.84E-18 T 28-03-2018 CIG75_RS04355 61ad7670c838dcd1be9e57ee554fe465 293 Pfam PF01545 Cation efflux family 16 207 8.4E-52 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CIG75_RS04355 61ad7670c838dcd1be9e57ee554fe465 293 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 12 289 6.2E-74 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CIG75_RS04355 61ad7670c838dcd1be9e57ee554fe465 293 SUPERFAMILY SSF161111 9 209 5.1E-58 T 28-03-2018 CIG75_RS04355 61ad7670c838dcd1be9e57ee554fe465 293 Gene3D G3DSA:3.30.70.1350 207 290 2.2E-15 T 28-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CIG75_RS04355 61ad7670c838dcd1be9e57ee554fe465 293 Pfam PF16916 Dimerisation domain of Zinc Transporter 212 287 4.5E-16 T 28-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CIG75_RS14540 910eb5bde2c74c352cdb725fbe538343 527 Hamap MF_00453 Phosphoenolpyruvate carboxykinase (ATP) [pckA]. 12 527 57.454 T 28-03-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 CIG75_RS14540 910eb5bde2c74c352cdb725fbe538343 527 Pfam PF01293 Phosphoenolpyruvate carboxykinase 18 481 4.3E-230 T 28-03-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 CIG75_RS14540 910eb5bde2c74c352cdb725fbe538343 527 TIGRFAM TIGR00224 pckA: phosphoenolpyruvate carboxykinase (ATP) 7 526 6.2E-243 T 28-03-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 CIG75_RS14540 910eb5bde2c74c352cdb725fbe538343 527 SUPERFAMILY SSF68923 11 212 3.14E-84 T 28-03-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CIG75_RS14540 910eb5bde2c74c352cdb725fbe538343 527 PIRSF PIRSF006294 1 527 2.5E-247 T 28-03-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 CIG75_RS14540 910eb5bde2c74c352cdb725fbe538343 527 Gene3D G3DSA:3.40.449.10 19 212 1.6E-81 T 28-03-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CIG75_RS14540 910eb5bde2c74c352cdb725fbe538343 527 Gene3D G3DSA:3.90.228.20 213 291 5.4E-29 T 28-03-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CIG75_RS14540 910eb5bde2c74c352cdb725fbe538343 527 Gene3D G3DSA:3.90.228.20 292 525 7.1E-102 T 28-03-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CIG75_RS14540 910eb5bde2c74c352cdb725fbe538343 527 SUPERFAMILY SSF53795 213 526 3.3E-139 T 28-03-2018 CIG75_RS14540 910eb5bde2c74c352cdb725fbe538343 527 ProSitePatterns PS00532 Phosphoenolpyruvate carboxykinase (ATP) signature. 250 265 - T 28-03-2018 IPR015994 Phosphoenolpyruvate carboxykinase (ATP), conserved site GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 CIG75_RS16065 2959efc8404160db5eea43d1a7bdd3a8 362 Gene3D G3DSA:1.10.3210.10 66 298 9.0E-43 T 28-03-2018 CIG75_RS16065 2959efc8404160db5eea43d1a7bdd3a8 362 Pfam PF01966 HD domain 136 257 3.0E-16 T 28-03-2018 IPR006674 HD domain CIG75_RS16065 2959efc8404160db5eea43d1a7bdd3a8 362 SUPERFAMILY SSF109604 125 292 3.4E-33 T 28-03-2018 CIG75_RS16065 2959efc8404160db5eea43d1a7bdd3a8 362 SMART SM00471 131 267 2.7E-10 T 28-03-2018 IPR003607 HD/PDEase domain CIG75_RS03250 07dd8b6ad9149823cbcab69febc3b0d6 206 Gene3D G3DSA:3.40.30.10 35 204 2.3E-35 T 28-03-2018 CIG75_RS03250 07dd8b6ad9149823cbcab69febc3b0d6 206 SUPERFAMILY SSF52833 45 205 9.44E-44 T 28-03-2018 IPR012336 Thioredoxin-like fold CIG75_RS03250 07dd8b6ad9149823cbcab69febc3b0d6 206 Pfam PF02630 SCO1/SenC 47 187 1.4E-23 T 28-03-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CIG75_RS09290 ea2302d7794938a0d2539481978baaa3 427 PRINTS PR01035 Tetracycline resistance protein signature 348 371 1.6E-6 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CIG75_RS09290 ea2302d7794938a0d2539481978baaa3 427 PRINTS PR01035 Tetracycline resistance protein signature 24 40 1.6E-6 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CIG75_RS09290 ea2302d7794938a0d2539481978baaa3 427 PRINTS PR01035 Tetracycline resistance protein signature 172 192 1.6E-6 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CIG75_RS09290 ea2302d7794938a0d2539481978baaa3 427 PRINTS PR01035 Tetracycline resistance protein signature 144 166 1.6E-6 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CIG75_RS09290 ea2302d7794938a0d2539481978baaa3 427 Gene3D G3DSA:1.20.1250.20 6 207 4.6E-34 T 28-03-2018 CIG75_RS09290 ea2302d7794938a0d2539481978baaa3 427 Gene3D G3DSA:1.20.1250.20 210 400 3.3E-24 T 28-03-2018 CIG75_RS09290 ea2302d7794938a0d2539481978baaa3 427 Pfam PF07690 Major Facilitator Superfamily 23 364 1.2E-53 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CIG75_RS09290 ea2302d7794938a0d2539481978baaa3 427 SUPERFAMILY SSF103473 5 396 6.28E-64 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS10840 be7673506fec0683e1087fc5a360842a 689 SUPERFAMILY SSF118116 498 687 7.19E-51 T 28-03-2018 CIG75_RS10840 be7673506fec0683e1087fc5a360842a 689 Pfam PF08676 MutL C terminal dimerisation domain 503 643 4.8E-36 T 28-03-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 CIG75_RS10840 be7673506fec0683e1087fc5a360842a 689 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 210 326 5.7E-39 T 28-03-2018 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 CIG75_RS10840 be7673506fec0683e1087fc5a360842a 689 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 3 307 4.7E-99 T 28-03-2018 IPR002099 DNA mismatch repair protein family GO:0005524|GO:0006298|GO:0030983 CIG75_RS10840 be7673506fec0683e1087fc5a360842a 689 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 94 100 - T 28-03-2018 IPR014762 DNA mismatch repair, conserved site CIG75_RS10840 be7673506fec0683e1087fc5a360842a 689 SMART SM00853 502 645 3.1E-43 T 28-03-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 CIG75_RS10840 be7673506fec0683e1087fc5a360842a 689 Gene3D G3DSA:3.30.230.10 214 326 1.1E-31 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CIG75_RS10840 be7673506fec0683e1087fc5a360842a 689 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 2 685 27.282 T 28-03-2018 IPR020667 DNA mismatch repair protein, MutL GO:0006298 CIG75_RS10840 be7673506fec0683e1087fc5a360842a 689 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 25 98 1.1E-8 T 28-03-2018 CIG75_RS10840 be7673506fec0683e1087fc5a360842a 689 SMART SM01340 209 327 7.5E-57 T 28-03-2018 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 CIG75_RS10840 be7673506fec0683e1087fc5a360842a 689 SUPERFAMILY SSF54211 190 327 3.3E-38 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CIG75_RS10840 be7673506fec0683e1087fc5a360842a 689 SUPERFAMILY SSF55874 3 215 1.44E-55 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS10840 be7673506fec0683e1087fc5a360842a 689 Gene3D G3DSA:3.30.565.10 2 202 7.2E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 Pfam PF00550 Phosphopantetheine attachment site 598 660 4.6E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 Pfam PF00550 Phosphopantetheine attachment site 2655 2716 3.6E-10 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 Pfam PF00550 Phosphopantetheine attachment site 3696 3762 8.1E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 Pfam PF00550 Phosphopantetheine attachment site 1620 1684 5.8E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 SUPERFAMILY SSF56801 3157 3706 4.06E-152 T 28-03-2018 CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 SUPERFAMILY SSF56801 1088 1632 1.16E-159 T 28-03-2018 CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 SUPERFAMILY SSF52777 682 845 1.33E-42 T 28-03-2018 CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1643 1658 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 SUPERFAMILY SSF52777 1876 2140 3.11E-62 T 28-03-2018 CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 Gene3D G3DSA:3.30.559.10 2725 2920 2.7E-36 T 28-03-2018 CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 Gene3D G3DSA:3.30.559.10 669 862 3.1E-41 T 28-03-2018 CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 Gene3D G3DSA:1.10.1200.10 2658 2724 6.5E-21 T 28-03-2018 CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 Gene3D G3DSA:1.10.1200.10 577 668 4.6E-19 T 28-03-2018 CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 SUPERFAMILY SSF52777 2924 3185 2.67E-57 T 28-03-2018 CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 SUPERFAMILY SSF47336 589 660 1.1E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 Pfam PF13193 AMP-binding enzyme C-terminal domain 2554 2627 4.8E-12 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 Pfam PF13193 AMP-binding enzyme C-terminal domain 1520 1593 2.3E-13 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 Pfam PF13193 AMP-binding enzyme C-terminal domain 3594 3667 6.9E-10 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 3221 3610 6.0E-129 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1151 1536 1.4E-128 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2175 2570 1.4E-130 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 SUPERFAMILY SSF56801 2113 2667 6.15E-156 T 28-03-2018 CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 Gene3D G3DSA:1.10.1200.10 1625 1700 4.5E-19 T 28-03-2018 CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 Gene3D G3DSA:3.40.50.980 2145 2298 1.3E-49 T 28-03-2018 CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 Gene3D G3DSA:3.40.50.980 14 177 3.1E-18 T 28-03-2018 CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 Gene3D G3DSA:3.40.50.980 1122 1275 1.7E-45 T 28-03-2018 CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 Gene3D G3DSA:3.40.50.980 3191 3344 3.4E-47 T 28-03-2018 CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 Gene3D G3DSA:3.30.300.30 3581 3699 7.0E-36 T 28-03-2018 CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 Gene3D G3DSA:3.30.300.30 2541 2657 9.1E-34 T 28-03-2018 CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 Gene3D G3DSA:3.30.300.30 1507 1624 3.0E-39 T 28-03-2018 CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 ProSitePatterns PS00018 EF-hand calcium-binding domain. 372 384 - T 28-03-2018 IPR018247 EF-Hand 1, calcium-binding site CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1269 1280 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 Pfam PF00668 Condensation domain 1701 2134 6.9E-133 T 28-03-2018 IPR001242 Condensation domain CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 Pfam PF00668 Condensation domain 678 1109 5.3E-126 T 28-03-2018 IPR001242 Condensation domain CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 Pfam PF00668 Condensation domain 2741 3180 2.9E-123 T 28-03-2018 IPR001242 Condensation domain CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 SUPERFAMILY SSF47336 3689 3766 1.14E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 SUPERFAMILY SSF47336 2646 2718 5.37E-17 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 Gene3D G3DSA:3.30.559.10 1701 1880 4.6E-37 T 28-03-2018 CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 SMART SM01294 3695 3762 0.0081 T 28-03-2018 CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 Gene3D G3DSA:3.40.50.980 1276 1422 8.9E-28 T 28-03-2018 CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 Gene3D G3DSA:3.40.50.980 3345 3497 1.0E-29 T 28-03-2018 CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 Gene3D G3DSA:3.40.50.980 178 355 2.4E-33 T 28-03-2018 CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 Gene3D G3DSA:3.40.50.980 2299 2456 6.3E-31 T 28-03-2018 CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2293 2304 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 SUPERFAMILY SSF56801 26 351 4.58E-89 T 28-03-2018 CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 SUPERFAMILY SSF56801 380 565 4.58E-89 T 28-03-2018 CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 Gene3D G3DSA:2.30.38.10 1423 1502 1.2E-27 T 28-03-2018 CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 Gene3D G3DSA:2.30.38.10 2457 2536 1.0E-25 T 28-03-2018 CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 Gene3D G3DSA:2.30.38.10 3498 3576 9.1E-26 T 28-03-2018 CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 SUPERFAMILY SSF47336 1612 1684 1.03E-17 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 Gene3D G3DSA:1.10.1200.10 3700 3768 1.9E-18 T 28-03-2018 CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 Gene3D G3DSA:2.30.38.10 385 457 1.3E-17 T 28-03-2018 CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 Gene3D G3DSA:3.30.300.30 458 563 2.5E-11 T 28-03-2018 CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 SUPERFAMILY SSF52777 852 1093 1.45E-64 T 28-03-2018 CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 SUPERFAMILY SSF52777 2747 2915 2.33E-41 T 28-03-2018 CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 Pfam PF00501 AMP-binding enzyme 32 463 2.2E-58 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 Pfam PF00501 AMP-binding enzyme 3200 3586 6.8E-97 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 Pfam PF00501 AMP-binding enzyme 2154 2546 2.8E-102 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 Pfam PF00501 AMP-binding enzyme 1130 1512 3.9E-101 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 SMART SM00823 Phosphopantetheine attachment site 2654 2723 0.029 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 SMART SM00823 Phosphopantetheine attachment site 3694 3766 5.4E-6 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 SMART SM00823 Phosphopantetheine attachment site 592 664 9.4E-4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 SMART SM00823 Phosphopantetheine attachment site 1619 1688 0.2 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 ProSitePatterns PS00455 Putative AMP-binding domain signature. 172 183 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 ProSitePatterns PS00455 Putative AMP-binding domain signature. 3339 3350 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS10620 5e3688b7983cf3708bc0958d5c0ec3dc 3783 SUPERFAMILY SSF52777 1702 1889 1.33E-41 T 28-03-2018 CIG75_RS10140 2d9603f18c11104e2affc8dd1a008e86 257 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 226 248 4.6E-9 T 28-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CIG75_RS10140 2d9603f18c11104e2affc8dd1a008e86 257 Gene3D G3DSA:3.40.50.300 1 247 3.8E-57 T 28-03-2018 CIG75_RS10140 2d9603f18c11104e2affc8dd1a008e86 257 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS10140 2d9603f18c11104e2affc8dd1a008e86 257 SMART SM00382 30 226 8.4E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS10140 2d9603f18c11104e2affc8dd1a008e86 257 Pfam PF00005 ABC transporter 22 177 1.8E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS10140 2d9603f18c11104e2affc8dd1a008e86 257 SUPERFAMILY SSF52540 4 246 8.04E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS06860 dd83423c95560189b3347834915d852c 415 SUPERFAMILY SSF55681 4 314 1.38E-98 T 28-03-2018 CIG75_RS06860 dd83423c95560189b3347834915d852c 415 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 5 403 1.3E-154 T 28-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 CIG75_RS06860 dd83423c95560189b3347834915d852c 415 PIRSF PIRSF001549 1 415 6.0E-126 T 28-03-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 CIG75_RS06860 dd83423c95560189b3347834915d852c 415 Pfam PF03129 Anticodon binding domain 325 413 1.2E-14 T 28-03-2018 IPR004154 Anticodon-binding CIG75_RS06860 dd83423c95560189b3347834915d852c 415 SUPERFAMILY SSF52954 322 413 6.71E-26 T 28-03-2018 IPR004154 Anticodon-binding CIG75_RS06860 dd83423c95560189b3347834915d852c 415 Gene3D G3DSA:3.40.50.800 320 415 8.1E-20 T 28-03-2018 IPR004154 Anticodon-binding CIG75_RS06860 dd83423c95560189b3347834915d852c 415 Gene3D G3DSA:3.30.930.10 1 317 1.4E-71 T 28-03-2018 CIG75_RS06860 dd83423c95560189b3347834915d852c 415 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 1 413 33.956 T 28-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 CIG75_RS06860 dd83423c95560189b3347834915d852c 415 Pfam PF13393 Histidyl-tRNA synthetase 8 306 2.7E-45 T 28-03-2018 CIG75_RS11665 bf959b496ab8e90ed0fa4cdb663984e3 347 SMART SM00471 127 262 1.4E-11 T 28-03-2018 IPR003607 HD/PDEase domain CIG75_RS11665 bf959b496ab8e90ed0fa4cdb663984e3 347 Pfam PF01966 HD domain 131 253 2.3E-17 T 28-03-2018 IPR006674 HD domain CIG75_RS11665 bf959b496ab8e90ed0fa4cdb663984e3 347 Gene3D G3DSA:1.10.3210.10 102 292 1.1E-42 T 28-03-2018 CIG75_RS11665 bf959b496ab8e90ed0fa4cdb663984e3 347 TIGRFAM TIGR00277 HDIG: HDIG domain 130 221 6.7E-8 T 28-03-2018 IPR006675 HDIG domain CIG75_RS11665 bf959b496ab8e90ed0fa4cdb663984e3 347 SUPERFAMILY SSF109604 122 290 1.04E-33 T 28-03-2018 CIG75_RS04575 64aee5451e9a1b56b31d30979c06a9f8 638 SUPERFAMILY SSF52540 310 505 8.15E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS04575 64aee5451e9a1b56b31d30979c06a9f8 638 Gene3D G3DSA:3.40.50.300 4 283 5.0E-56 T 28-03-2018 CIG75_RS04575 64aee5451e9a1b56b31d30979c06a9f8 638 SMART SM00382 343 521 8.4E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS04575 64aee5451e9a1b56b31d30979c06a9f8 638 SMART SM00382 28 232 1.3E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS04575 64aee5451e9a1b56b31d30979c06a9f8 638 Pfam PF00005 ABC transporter 338 469 1.1E-20 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS04575 64aee5451e9a1b56b31d30979c06a9f8 638 Pfam PF00005 ABC transporter 20 187 7.9E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS04575 64aee5451e9a1b56b31d30979c06a9f8 638 Pfam PF16326 ABC transporter C-terminal domain 560 626 1.5E-17 T 28-03-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 CIG75_RS04575 64aee5451e9a1b56b31d30979c06a9f8 638 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS04575 64aee5451e9a1b56b31d30979c06a9f8 638 Gene3D G3DSA:3.40.50.300 284 551 1.4E-51 T 28-03-2018 CIG75_RS04575 64aee5451e9a1b56b31d30979c06a9f8 638 Pfam PF12848 ABC transporter 226 304 1.0E-11 T 28-03-2018 IPR032781 ABC-transporter extension domain CIG75_RS04575 64aee5451e9a1b56b31d30979c06a9f8 638 SUPERFAMILY SSF52540 6 240 1.58E-49 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS15865 d82203334a86b7c6526ee960b5b269ec 536 Gene3D G3DSA:1.10.287.130 311 379 2.3E-12 T 28-03-2018 CIG75_RS15865 d82203334a86b7c6526ee960b5b269ec 536 SMART SM00388 317 383 1.7E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CIG75_RS15865 d82203334a86b7c6526ee960b5b269ec 536 Gene3D G3DSA:3.30.450.20 182 310 6.8E-6 T 28-03-2018 CIG75_RS15865 d82203334a86b7c6526ee960b5b269ec 536 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 426 531 8.4E-24 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS15865 d82203334a86b7c6526ee960b5b269ec 536 PRINTS PR00344 Bacterial sensor protein C-terminal signature 464 478 1.4E-17 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS15865 d82203334a86b7c6526ee960b5b269ec 536 PRINTS PR00344 Bacterial sensor protein C-terminal signature 482 492 1.4E-17 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS15865 d82203334a86b7c6526ee960b5b269ec 536 PRINTS PR00344 Bacterial sensor protein C-terminal signature 493 511 1.4E-17 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS15865 d82203334a86b7c6526ee960b5b269ec 536 PRINTS PR00344 Bacterial sensor protein C-terminal signature 517 530 1.4E-17 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS15865 d82203334a86b7c6526ee960b5b269ec 536 SMART SM00387 424 533 9.6E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS15865 d82203334a86b7c6526ee960b5b269ec 536 Pfam PF01590 GAF domain 74 176 5.2E-5 T 28-03-2018 IPR003018 GAF domain GO:0005515 CIG75_RS15865 d82203334a86b7c6526ee960b5b269ec 536 Pfam PF00512 His Kinase A (phospho-acceptor) domain 318 381 5.3E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CIG75_RS15865 d82203334a86b7c6526ee960b5b269ec 536 SUPERFAMILY SSF47384 309 381 1.28E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CIG75_RS15865 d82203334a86b7c6526ee960b5b269ec 536 Gene3D G3DSA:3.30.450.40 79 181 5.5E-4 T 28-03-2018 IPR029016 GAF domain-like CIG75_RS15865 d82203334a86b7c6526ee960b5b269ec 536 Gene3D G3DSA:3.30.565.10 384 535 6.2E-41 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS15865 d82203334a86b7c6526ee960b5b269ec 536 SUPERFAMILY SSF55874 373 531 6.94E-43 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS15190 8e9c83bb16bbfe6ba48cf517ad7d19a3 321 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 76 4.0E-20 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CIG75_RS15190 8e9c83bb16bbfe6ba48cf517ad7d19a3 321 SUPERFAMILY SSF46785 5 80 4.42E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS15190 8e9c83bb16bbfe6ba48cf517ad7d19a3 321 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 50 66 3.9E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CIG75_RS15190 8e9c83bb16bbfe6ba48cf517ad7d19a3 321 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 36 50 3.9E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CIG75_RS15190 8e9c83bb16bbfe6ba48cf517ad7d19a3 321 SMART SM00345 17 76 4.7E-23 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CIG75_RS15190 8e9c83bb16bbfe6ba48cf517ad7d19a3 321 Gene3D G3DSA:1.10.10.10 2 77 1.5E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS05370 3d0ca6601c1b63e961019261e31fcdb6 430 SUPERFAMILY SSF48452 187 342 5.03E-16 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS05370 3d0ca6601c1b63e961019261e31fcdb6 430 Pfam PF13181 Tetratricopeptide repeat 389 414 0.0013 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS05370 3d0ca6601c1b63e961019261e31fcdb6 430 Gene3D G3DSA:1.25.40.10 242 425 5.0E-25 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS05370 3d0ca6601c1b63e961019261e31fcdb6 430 Gene3D G3DSA:1.25.40.10 78 163 3.1E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS05370 3d0ca6601c1b63e961019261e31fcdb6 430 Pfam PF12844 Helix-turn-helix domain 6 64 1.1E-11 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS05370 3d0ca6601c1b63e961019261e31fcdb6 430 Pfam PF13424 Tetratricopeptide repeat 151 220 6.2E-10 T 28-03-2018 CIG75_RS05370 3d0ca6601c1b63e961019261e31fcdb6 430 SUPERFAMILY SSF48452 306 417 3.07E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS05370 3d0ca6601c1b63e961019261e31fcdb6 430 SUPERFAMILY SSF48452 76 223 1.16E-16 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS05370 3d0ca6601c1b63e961019261e31fcdb6 430 Gene3D G3DSA:1.25.40.10 202 241 6.8E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS05370 3d0ca6601c1b63e961019261e31fcdb6 430 Gene3D G3DSA:1.25.40.10 164 201 1.7E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS05370 3d0ca6601c1b63e961019261e31fcdb6 430 SUPERFAMILY SSF47413 3 66 2.45E-14 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CIG75_RS05370 3d0ca6601c1b63e961019261e31fcdb6 430 SMART SM00028 149 182 0.26 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS05370 3d0ca6601c1b63e961019261e31fcdb6 430 SMART SM00028 109 142 45.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS05370 3d0ca6601c1b63e961019261e31fcdb6 430 SMART SM00028 191 224 0.039 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS05370 3d0ca6601c1b63e961019261e31fcdb6 430 SMART SM00028 349 382 500.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS05370 3d0ca6601c1b63e961019261e31fcdb6 430 SMART SM00028 311 344 1.2 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS05370 3d0ca6601c1b63e961019261e31fcdb6 430 SMART SM00028 231 264 19.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS05370 3d0ca6601c1b63e961019261e31fcdb6 430 SMART SM00028 389 422 4.8 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS05370 3d0ca6601c1b63e961019261e31fcdb6 430 Pfam PF13432 Tetratricopeptide repeat 76 135 0.006 T 28-03-2018 CIG75_RS05370 3d0ca6601c1b63e961019261e31fcdb6 430 SMART SM00530 8 62 1.2E-12 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS05370 3d0ca6601c1b63e961019261e31fcdb6 430 Gene3D G3DSA:1.10.260.40 1 77 2.2E-16 T 28-03-2018 CIG75_RS11045 d3f259b74dce5c42b1cf7857fc158226 2154 SMART SM00823 Phosphopantetheine attachment site 2066 2135 0.0016 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS11045 d3f259b74dce5c42b1cf7857fc158226 2154 SMART SM00823 Phosphopantetheine attachment site 1013 1082 0.0099 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS11045 d3f259b74dce5c42b1cf7857fc158226 2154 Gene3D G3DSA:1.10.1220.10 255 311 0.082 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CIG75_RS11045 d3f259b74dce5c42b1cf7857fc158226 2154 Gene3D G3DSA:3.30.300.30 902 1019 3.2E-39 T 28-03-2018 CIG75_RS11045 d3f259b74dce5c42b1cf7857fc158226 2154 Gene3D G3DSA:3.30.300.30 1960 2071 1.9E-34 T 28-03-2018 CIG75_RS11045 d3f259b74dce5c42b1cf7857fc158226 2154 Gene3D G3DSA:1.10.1200.10 2072 2138 6.8E-23 T 28-03-2018 CIG75_RS11045 d3f259b74dce5c42b1cf7857fc158226 2154 Gene3D G3DSA:1.10.1200.10 1020 1081 2.4E-21 T 28-03-2018 CIG75_RS11045 d3f259b74dce5c42b1cf7857fc158226 2154 SUPERFAMILY SSF52777 47 224 3.11E-49 T 28-03-2018 CIG75_RS11045 d3f259b74dce5c42b1cf7857fc158226 2154 Gene3D G3DSA:3.30.559.10 1082 1278 1.4E-38 T 28-03-2018 CIG75_RS11045 d3f259b74dce5c42b1cf7857fc158226 2154 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1701 1712 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS11045 d3f259b74dce5c42b1cf7857fc158226 2154 SUPERFAMILY SSF52777 1105 1275 7.89E-50 T 28-03-2018 CIG75_RS11045 d3f259b74dce5c42b1cf7857fc158226 2154 Gene3D G3DSA:3.40.50.980 1706 1867 4.5E-29 T 28-03-2018 CIG75_RS11045 d3f259b74dce5c42b1cf7857fc158226 2154 Gene3D G3DSA:3.40.50.980 653 818 7.2E-40 T 28-03-2018 CIG75_RS11045 d3f259b74dce5c42b1cf7857fc158226 2154 SUPERFAMILY SSF52777 1283 1523 3.34E-71 T 28-03-2018 CIG75_RS11045 d3f259b74dce5c42b1cf7857fc158226 2154 Gene3D G3DSA:2.30.38.10 819 897 5.8E-23 T 28-03-2018 CIG75_RS11045 d3f259b74dce5c42b1cf7857fc158226 2154 Gene3D G3DSA:2.30.38.10 1875 1955 1.9E-24 T 28-03-2018 CIG75_RS11045 d3f259b74dce5c42b1cf7857fc158226 2154 SUPERFAMILY SSF56801 1518 2077 2.35E-150 T 28-03-2018 CIG75_RS11045 d3f259b74dce5c42b1cf7857fc158226 2154 Gene3D G3DSA:3.30.559.10 22 247 1.0E-45 T 28-03-2018 CIG75_RS11045 d3f259b74dce5c42b1cf7857fc158226 2154 Pfam PF00501 AMP-binding enzyme 508 907 8.2E-102 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS11045 d3f259b74dce5c42b1cf7857fc158226 2154 Pfam PF00501 AMP-binding enzyme 1559 1965 1.5E-92 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS11045 d3f259b74dce5c42b1cf7857fc158226 2154 Gene3D G3DSA:3.40.50.980 500 652 1.1E-48 T 28-03-2018 CIG75_RS11045 d3f259b74dce5c42b1cf7857fc158226 2154 SUPERFAMILY SSF56801 465 1026 3.4E-165 T 28-03-2018 CIG75_RS11045 d3f259b74dce5c42b1cf7857fc158226 2154 SUPERFAMILY SSF52777 231 492 4.11E-66 T 28-03-2018 CIG75_RS11045 d3f259b74dce5c42b1cf7857fc158226 2154 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2090 2105 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS11045 d3f259b74dce5c42b1cf7857fc158226 2154 Gene3D G3DSA:3.40.50.980 1552 1705 5.0E-47 T 28-03-2018 CIG75_RS11045 d3f259b74dce5c42b1cf7857fc158226 2154 ProSitePatterns PS00455 Putative AMP-binding domain signature. 647 658 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS11045 d3f259b74dce5c42b1cf7857fc158226 2154 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1037 1052 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS11045 d3f259b74dce5c42b1cf7857fc158226 2154 Pfam PF00550 Phosphopantetheine attachment site 2068 2131 2.8E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS11045 d3f259b74dce5c42b1cf7857fc158226 2154 Pfam PF00550 Phosphopantetheine attachment site 1016 1078 6.1E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS11045 d3f259b74dce5c42b1cf7857fc158226 2154 Pfam PF00668 Condensation domain 42 488 3.7E-117 T 28-03-2018 IPR001242 Condensation domain CIG75_RS11045 d3f259b74dce5c42b1cf7857fc158226 2154 Pfam PF00668 Condensation domain 1100 1540 1.7E-118 T 28-03-2018 IPR001242 Condensation domain CIG75_RS11045 d3f259b74dce5c42b1cf7857fc158226 2154 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1580 1989 3.0E-127 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS11045 d3f259b74dce5c42b1cf7857fc158226 2154 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 529 931 1.0E-128 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS11045 d3f259b74dce5c42b1cf7857fc158226 2154 SUPERFAMILY SSF47336 1005 1078 4.06E-18 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS11045 d3f259b74dce5c42b1cf7857fc158226 2154 Pfam PF13193 AMP-binding enzyme C-terminal domain 1973 2040 1.1E-6 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS11045 d3f259b74dce5c42b1cf7857fc158226 2154 Pfam PF13193 AMP-binding enzyme C-terminal domain 915 985 1.9E-12 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS11045 d3f259b74dce5c42b1cf7857fc158226 2154 SUPERFAMILY SSF47336 2058 2131 4.19E-19 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS05570 ff37914c8402dce452d153c1a733ce73 131 Pfam PF04186 FxsA cytoplasmic membrane protein 8 112 8.8E-34 T 28-03-2018 IPR007313 FxsA cytoplasmic membrane protein GO:0016020 CIG75_RS09240 6ca2f0c16ef46150f596e7767b55bb7e 395 Gene3D G3DSA:3.40.50.1100 87 193 2.8E-22 T 28-03-2018 CIG75_RS09240 6ca2f0c16ef46150f596e7767b55bb7e 395 SUPERFAMILY SSF53686 7 381 4.19E-64 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CIG75_RS09240 6ca2f0c16ef46150f596e7767b55bb7e 395 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 74 372 8.9E-58 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CIG75_RS09240 6ca2f0c16ef46150f596e7767b55bb7e 395 Gene3D G3DSA:3.40.50.1100 194 384 1.9E-25 T 28-03-2018 CIG75_RS00860 4bffde9c33f8c796dfbe11fe4339d6ad 308 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 4 306 1.7E-14 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CIG75_RS00860 4bffde9c33f8c796dfbe11fe4339d6ad 308 Gene3D G3DSA:3.40.50.720 108 283 7.2E-58 T 28-03-2018 CIG75_RS00860 4bffde9c33f8c796dfbe11fe4339d6ad 308 Gene3D G3DSA:3.40.50.720 1 107 1.0E-20 T 28-03-2018 CIG75_RS00860 4bffde9c33f8c796dfbe11fe4339d6ad 308 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 220 236 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CIG75_RS00860 4bffde9c33f8c796dfbe11fe4339d6ad 308 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 102 280 1.9E-58 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CIG75_RS00860 4bffde9c33f8c796dfbe11fe4339d6ad 308 SUPERFAMILY SSF51735 93 281 6.9E-57 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS00860 4bffde9c33f8c796dfbe11fe4339d6ad 308 SUPERFAMILY SSF52283 1 128 2.13E-19 T 28-03-2018 CIG75_RS17500 0c53f74ec36dbc429ded22c4aa453eae 206 Gene3D G3DSA:1.10.357.10 63 205 1.8E-7 T 28-03-2018 CIG75_RS17500 0c53f74ec36dbc429ded22c4aa453eae 206 Gene3D G3DSA:1.10.10.60 5 62 6.7E-11 T 28-03-2018 CIG75_RS17500 0c53f74ec36dbc429ded22c4aa453eae 206 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 59 2.6E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CIG75_RS17500 0c53f74ec36dbc429ded22c4aa453eae 206 SUPERFAMILY SSF46689 9 69 2.26E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CIG75_RS20230 174efc1146ae5b886a00aca06a832472 99 Pfam PF01479 S4 domain 1 47 8.5E-12 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CIG75_RS20230 174efc1146ae5b886a00aca06a832472 99 SUPERFAMILY SSF55174 1 78 4.06E-20 T 28-03-2018 CIG75_RS20230 174efc1146ae5b886a00aca06a832472 99 SMART SM00363 1 61 1.4E-10 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CIG75_RS20230 174efc1146ae5b886a00aca06a832472 99 Gene3D G3DSA:3.10.290.10 1 96 3.7E-17 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CIG75_RS20230 174efc1146ae5b886a00aca06a832472 99 PIRSF PIRSF038881 1 87 7.6E-32 T 28-03-2018 IPR025490 RNA-binding protein, HP1423 type CIG75_RS09005 1af7c587a8e09531ddcfab1d8c182d31 183 Pfam PF03358 NADPH-dependent FMN reductase 1 137 6.9E-36 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CIG75_RS09005 1af7c587a8e09531ddcfab1d8c182d31 183 Gene3D G3DSA:3.40.50.360 1 182 2.2E-40 T 28-03-2018 IPR029039 Flavoprotein-like domain CIG75_RS09005 1af7c587a8e09531ddcfab1d8c182d31 183 SUPERFAMILY SSF52218 1 174 8.38E-43 T 28-03-2018 IPR029039 Flavoprotein-like domain CIG75_RS00930 6a88669c523064a02fa4ee46a099a06a 567 Gene3D G3DSA:1.10.10.60 264 306 1.9E-12 T 28-03-2018 CIG75_RS00930 6a88669c523064a02fa4ee46a099a06a 567 SUPERFAMILY SSF53807 302 557 9.03E-37 T 28-03-2018 CIG75_RS00930 6a88669c523064a02fa4ee46a099a06a 567 SUPERFAMILY SSF46689 199 247 5.87E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CIG75_RS00930 6a88669c523064a02fa4ee46a099a06a 567 SUPERFAMILY SSF46689 249 299 1.08E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CIG75_RS00930 6a88669c523064a02fa4ee46a099a06a 567 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 250 292 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CIG75_RS00930 6a88669c523064a02fa4ee46a099a06a 567 SMART SM00342 213 296 5.2E-27 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CIG75_RS00930 6a88669c523064a02fa4ee46a099a06a 567 Gene3D G3DSA:3.40.50.1980 412 565 1.7E-25 T 28-03-2018 CIG75_RS00930 6a88669c523064a02fa4ee46a099a06a 567 Gene3D G3DSA:2.60.120.10 28 117 0.0013 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CIG75_RS00930 6a88669c523064a02fa4ee46a099a06a 567 Pfam PF01497 Periplasmic binding protein 348 536 3.8E-22 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CIG75_RS00930 6a88669c523064a02fa4ee46a099a06a 567 Gene3D G3DSA:3.90.1240.10 158 263 3.4E-23 T 28-03-2018 CIG75_RS00930 6a88669c523064a02fa4ee46a099a06a 567 Pfam PF12833 Helix-turn-helix domain 219 297 1.7E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CIG75_RS00930 6a88669c523064a02fa4ee46a099a06a 567 Gene3D G3DSA:3.40.50.1980 307 411 8.5E-10 T 28-03-2018 CIG75_RS04425 ffa7c614f15eb3db9948a925f01bfdb4 337 SUPERFAMILY SSF55874 168 334 5.76E-47 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS04425 ffa7c614f15eb3db9948a925f01bfdb4 337 PRINTS PR00344 Bacterial sensor protein C-terminal signature 260 274 1.1E-19 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS04425 ffa7c614f15eb3db9948a925f01bfdb4 337 PRINTS PR00344 Bacterial sensor protein C-terminal signature 278 288 1.1E-19 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS04425 ffa7c614f15eb3db9948a925f01bfdb4 337 PRINTS PR00344 Bacterial sensor protein C-terminal signature 295 313 1.1E-19 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS04425 ffa7c614f15eb3db9948a925f01bfdb4 337 PRINTS PR00344 Bacterial sensor protein C-terminal signature 319 332 1.1E-19 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS04425 ffa7c614f15eb3db9948a925f01bfdb4 337 Gene3D G3DSA:1.10.287.130 104 158 2.4E-13 T 28-03-2018 CIG75_RS04425 ffa7c614f15eb3db9948a925f01bfdb4 337 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 224 333 3.6E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS04425 ffa7c614f15eb3db9948a925f01bfdb4 337 SMART SM00388 114 178 2.3E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CIG75_RS04425 ffa7c614f15eb3db9948a925f01bfdb4 337 Gene3D G3DSA:3.30.565.10 159 334 6.4E-47 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS04425 ffa7c614f15eb3db9948a925f01bfdb4 337 Pfam PF00512 His Kinase A (phospho-acceptor) domain 114 177 1.4E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CIG75_RS04425 ffa7c614f15eb3db9948a925f01bfdb4 337 SUPERFAMILY SSF47384 97 178 6.67E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CIG75_RS04425 ffa7c614f15eb3db9948a925f01bfdb4 337 SMART SM00387 223 335 1.3E-42 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS17195 840d422991af2add61166351afe2fcc6 575 Gene3D G3DSA:1.25.40.10 21 74 2.1E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS17195 840d422991af2add61166351afe2fcc6 575 Gene3D G3DSA:1.25.40.10 75 165 1.7E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS17195 840d422991af2add61166351afe2fcc6 575 SUPERFAMILY SSF48452 167 330 2.61E-23 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS17195 840d422991af2add61166351afe2fcc6 575 SUPERFAMILY SSF48452 25 129 7.85E-21 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS17195 840d422991af2add61166351afe2fcc6 575 Pfam PF13432 Tetratricopeptide repeat 64 127 0.0044 T 28-03-2018 CIG75_RS17195 840d422991af2add61166351afe2fcc6 575 Gene3D G3DSA:1.25.40.10 166 203 7.4E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS17195 840d422991af2add61166351afe2fcc6 575 SMART SM00028 194 227 0.0062 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS17195 840d422991af2add61166351afe2fcc6 575 SMART SM00028 25 58 0.039 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS17195 840d422991af2add61166351afe2fcc6 575 SMART SM00028 160 193 350.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS17195 840d422991af2add61166351afe2fcc6 575 SMART SM00028 94 127 16.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS17195 840d422991af2add61166351afe2fcc6 575 SMART SM00028 297 330 430.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS17195 840d422991af2add61166351afe2fcc6 575 Gene3D G3DSA:1.25.40.10 262 367 9.1E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS17195 840d422991af2add61166351afe2fcc6 575 Gene3D G3DSA:1.25.40.10 204 261 4.6E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS17195 840d422991af2add61166351afe2fcc6 575 Pfam PF14559 Tetratricopeptide repeat 170 231 3.2E-7 T 28-03-2018 CIG75_RS17195 840d422991af2add61166351afe2fcc6 575 Gene3D G3DSA:1.10.10.10 488 567 0.0017 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS07535 bfbb57a9a6ce57cf67660446bb16c63f 89 Pfam PF01541 GIY-YIG catalytic domain 2 67 7.9E-12 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CIG75_RS07535 bfbb57a9a6ce57cf67660446bb16c63f 89 Gene3D G3DSA:3.40.1440.10 1 80 1.3E-5 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CIG75_RS07535 bfbb57a9a6ce57cf67660446bb16c63f 89 SUPERFAMILY SSF82771 2 72 1.83E-12 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CIG75_RS08595 0f089972a9affc8bae2af4aedbfcbd1e 710 SUPERFAMILY SSF52540 201 447 3.19E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS08595 0f089972a9affc8bae2af4aedbfcbd1e 710 SUPERFAMILY SSF47819 517 591 4.86E-24 T 28-03-2018 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 CIG75_RS08595 0f089972a9affc8bae2af4aedbfcbd1e 710 Gene3D G3DSA:1.10.150.80 507 596 1.1E-26 T 28-03-2018 CIG75_RS08595 0f089972a9affc8bae2af4aedbfcbd1e 710 SUPERFAMILY SSF52540 5 157 6.21E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS08595 0f089972a9affc8bae2af4aedbfcbd1e 710 SUPERFAMILY SSF52540 298 339 6.21E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS08595 0f089972a9affc8bae2af4aedbfcbd1e 710 SMART SM00956 405 508 2.7E-44 T 28-03-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 CIG75_RS08595 0f089972a9affc8bae2af4aedbfcbd1e 710 Pfam PF09382 RQC domain 402 507 2.2E-35 T 28-03-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 CIG75_RS08595 0f089972a9affc8bae2af4aedbfcbd1e 710 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 8 455 4.1E-146 T 28-03-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 CIG75_RS08595 0f089972a9affc8bae2af4aedbfcbd1e 710 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 7 587 1.8E-238 T 28-03-2018 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 CIG75_RS08595 0f089972a9affc8bae2af4aedbfcbd1e 710 Pfam PF00270 DEAD/DEAH box helicase 21 181 9.3E-19 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CIG75_RS08595 0f089972a9affc8bae2af4aedbfcbd1e 710 Gene3D G3DSA:1.10.10.10 347 506 5.5E-51 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS08595 0f089972a9affc8bae2af4aedbfcbd1e 710 Pfam PF00570 HRDC domain 519 583 9.5E-22 T 28-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 CIG75_RS08595 0f089972a9affc8bae2af4aedbfcbd1e 710 Pfam PF14493 Helix-turn-helix domain 614 699 7.3E-27 T 28-03-2018 IPR029491 Helicase Helix-turn-helix domain Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 CIG75_RS08595 0f089972a9affc8bae2af4aedbfcbd1e 710 Gene3D G3DSA:3.40.50.300 1 201 6.1E-31 T 28-03-2018 CIG75_RS08595 0f089972a9affc8bae2af4aedbfcbd1e 710 SMART SM00490 243 324 1.8E-21 T 28-03-2018 IPR001650 Helicase, C-terminal CIG75_RS08595 0f089972a9affc8bae2af4aedbfcbd1e 710 Pfam PF00271 Helicase conserved C-terminal domain 221 323 1.9E-15 T 28-03-2018 IPR001650 Helicase, C-terminal CIG75_RS08595 0f089972a9affc8bae2af4aedbfcbd1e 710 SMART SM00487 14 211 2.9E-27 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CIG75_RS08595 0f089972a9affc8bae2af4aedbfcbd1e 710 SMART SM00341 514 594 1.7E-19 T 28-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 CIG75_RS08595 0f089972a9affc8bae2af4aedbfcbd1e 710 Pfam PF16124 RecQ zinc-binding 335 398 1.2E-16 T 28-03-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain CIG75_RS08595 0f089972a9affc8bae2af4aedbfcbd1e 710 Gene3D G3DSA:3.40.50.300 203 346 2.3E-29 T 28-03-2018 CIG75_RS02495 79d6cb20cb72b12d062d27effb19fa56 197 Pfam PF04542 Sigma-70 region 2 23 89 3.5E-22 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS02495 79d6cb20cb72b12d062d27effb19fa56 197 Pfam PF08281 Sigma-70, region 4 127 180 5.4E-18 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS02495 79d6cb20cb72b12d062d27effb19fa56 197 SUPERFAMILY SSF88946 5 98 8.48E-31 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS02495 79d6cb20cb72b12d062d27effb19fa56 197 SUPERFAMILY SSF88659 116 184 2.43E-17 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS02495 79d6cb20cb72b12d062d27effb19fa56 197 TIGRFAM TIGR02948 SigW_bacill: RNA polymerase sigma-W factor 1 185 5.0E-84 T 28-03-2018 IPR014294 RNA polymerase sigma-W, bacillaceae CIG75_RS02495 79d6cb20cb72b12d062d27effb19fa56 197 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 45 76 - T 28-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS02495 79d6cb20cb72b12d062d27effb19fa56 197 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 19 183 2.0E-36 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS02495 79d6cb20cb72b12d062d27effb19fa56 197 Gene3D G3DSA:1.10.10.10 92 187 7.7E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS02495 79d6cb20cb72b12d062d27effb19fa56 197 Gene3D G3DSA:1.10.1740.10 1 91 5.3E-28 T 28-03-2018 CIG75_RS19265 03ee007e9f622cf556c298345ba9c8dc 134 Gene3D G3DSA:1.10.260.40 72 129 0.14 T 28-03-2018 CIG75_RS19265 03ee007e9f622cf556c298345ba9c8dc 134 Gene3D G3DSA:1.10.260.40 1 71 2.4E-18 T 28-03-2018 CIG75_RS19265 03ee007e9f622cf556c298345ba9c8dc 134 SMART SM00530 7 62 6.3E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS19265 03ee007e9f622cf556c298345ba9c8dc 134 Pfam PF12844 Helix-turn-helix domain 5 67 2.2E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS19265 03ee007e9f622cf556c298345ba9c8dc 134 SUPERFAMILY SSF47413 1 70 1.77E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CIG75_RS20285 73004375402da4856080fa06831d1c0c 214 SUPERFAMILY SSF50715 4 185 8.2E-39 T 28-03-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CIG75_RS20285 73004375402da4856080fa06831d1c0c 214 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 98 181 8.4E-21 T 28-03-2018 IPR020057 Ribosomal protein L25, beta domain CIG75_RS20285 73004375402da4856080fa06831d1c0c 214 Gene3D G3DSA:2.170.120.20 97 186 1.1E-21 T 28-03-2018 IPR020057 Ribosomal protein L25, beta domain CIG75_RS20285 73004375402da4856080fa06831d1c0c 214 Pfam PF01386 Ribosomal L25p family 6 90 1.5E-17 T 28-03-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 CIG75_RS20285 73004375402da4856080fa06831d1c0c 214 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 6 179 5.5E-36 T 28-03-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 CIG75_RS20285 73004375402da4856080fa06831d1c0c 214 Gene3D G3DSA:2.40.240.10 3 92 8.3E-18 T 28-03-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CIG75_RS20285 73004375402da4856080fa06831d1c0c 214 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 4 182 22.143 T 28-03-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 CIG75_RS20285 73004375402da4856080fa06831d1c0c 214 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 8 91 2.0E-8 T 28-03-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 CIG75_RS09485 d515a3c8d465d67cfa374bb2a86bc3a1 238 Pfam PF04555 Restriction endonuclease XhoI 25 208 3.2E-47 T 28-03-2018 IPR007636 Restriction endonuclease, type II, XhoI GO:0003677|GO:0009036|GO:0009307 CIG75_RS01305 a1168d4ddcd72cbd8a44b94c938cc0fe 228 Gene3D G3DSA:3.40.50.2020 3 188 6.3E-24 T 28-03-2018 CIG75_RS01305 a1168d4ddcd72cbd8a44b94c938cc0fe 228 SUPERFAMILY SSF53271 1 186 1.2E-40 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CIG75_RS01305 a1168d4ddcd72cbd8a44b94c938cc0fe 228 Pfam PF00156 Phosphoribosyl transferase domain 42 157 8.0E-10 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CIG75_RS01305 a1168d4ddcd72cbd8a44b94c938cc0fe 228 TIGRFAM TIGR01744 XPRTase: xanthine phosphoribosyltransferase 1 188 9.8E-76 T 28-03-2018 IPR010079 Xanthine phosphoribosyltransferase GO:0016763|GO:0043101|GO:0046110 KEGG: 00230+2.4.2.22 CIG75_RS01305 a1168d4ddcd72cbd8a44b94c938cc0fe 228 Hamap MF_01184 Xanthine phosphoribosyltransferase [xpt]. 1 189 38.54 T 28-03-2018 IPR010079 Xanthine phosphoribosyltransferase GO:0016763|GO:0043101|GO:0046110 KEGG: 00230+2.4.2.22 CIG75_RS09245 213e50c6e50927e57bf18008f3513f3e 534 SUPERFAMILY SSF51445 311 347 1.48E-40 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CIG75_RS09245 213e50c6e50927e57bf18008f3513f3e 534 SUPERFAMILY SSF51445 51 241 1.48E-40 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CIG75_RS09245 213e50c6e50927e57bf18008f3513f3e 534 Pfam PF00704 Glycosyl hydrolases family 18 37 339 1.6E-30 T 28-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 CIG75_RS09245 213e50c6e50927e57bf18008f3513f3e 534 Gene3D G3DSA:3.20.20.80 23 363 5.2E-46 T 28-03-2018 CIG75_RS09245 213e50c6e50927e57bf18008f3513f3e 534 SMART SM00636 37 340 8.8E-8 T 28-03-2018 IPR011583 Chitinase II GO:0008061 CIG75_RS09245 213e50c6e50927e57bf18008f3513f3e 534 Pfam PF00395 S-layer homology domain 477 519 1.7E-12 T 28-03-2018 IPR001119 S-layer homology domain CIG75_RS09245 213e50c6e50927e57bf18008f3513f3e 534 Pfam PF00395 S-layer homology domain 359 398 1.9E-4 T 28-03-2018 IPR001119 S-layer homology domain CIG75_RS09245 213e50c6e50927e57bf18008f3513f3e 534 Pfam PF00395 S-layer homology domain 417 459 1.4E-8 T 28-03-2018 IPR001119 S-layer homology domain CIG75_RS02270 e4831b7299c1572b9a9cd3ad2b642f1e 744 SUPERFAMILY SSF52540 186 495 1.39E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS02270 e4831b7299c1572b9a9cd3ad2b642f1e 744 Pfam PF13538 UvrD-like helicase C-terminal domain 660 707 7.7E-21 T 28-03-2018 IPR027785 UvrD-like helicase C-terminal domain CIG75_RS02270 e4831b7299c1572b9a9cd3ad2b642f1e 744 Pfam PF14520 Helix-hairpin-helix domain 95 146 5.1E-9 T 28-03-2018 CIG75_RS02270 e4831b7299c1572b9a9cd3ad2b642f1e 744 Gene3D G3DSA:3.40.50.300 288 506 1.0E-37 T 28-03-2018 CIG75_RS02270 e4831b7299c1572b9a9cd3ad2b642f1e 744 SMART SM00278 188 207 110.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CIG75_RS02270 e4831b7299c1572b9a9cd3ad2b642f1e 744 SMART SM00278 124 143 88.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CIG75_RS02270 e4831b7299c1572b9a9cd3ad2b642f1e 744 SMART SM00278 89 110 930.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CIG75_RS02270 e4831b7299c1572b9a9cd3ad2b642f1e 744 Gene3D G3DSA:1.10.150.280 132 211 2.3E-6 T 28-03-2018 CIG75_RS02270 e4831b7299c1572b9a9cd3ad2b642f1e 744 Gene3D G3DSA:1.10.150.280 70 103 0.44 T 28-03-2018 CIG75_RS02270 e4831b7299c1572b9a9cd3ad2b642f1e 744 Hamap MF_01488 ATP-dependent RecD-like DNA helicase [recD2]. 8 736 28.77 T 28-03-2018 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 CIG75_RS02270 e4831b7299c1572b9a9cd3ad2b642f1e 744 SMART SM00382 347 498 5.9E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS02270 e4831b7299c1572b9a9cd3ad2b642f1e 744 Pfam PF13604 AAA domain 334 515 2.9E-43 T 28-03-2018 CIG75_RS02270 e4831b7299c1572b9a9cd3ad2b642f1e 744 SUPERFAMILY SSF47781 89 147 5.93E-10 T 28-03-2018 IPR010994 RuvA domain 2-like CIG75_RS02270 e4831b7299c1572b9a9cd3ad2b642f1e 744 TIGRFAM TIGR01448 recD_rel: helicase, RecD/TraA family 12 733 4.2E-217 T 28-03-2018 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 CIG75_RS02270 e4831b7299c1572b9a9cd3ad2b642f1e 744 Gene3D G3DSA:3.40.50.300 507 720 3.0E-34 T 28-03-2018 CIG75_RS02270 e4831b7299c1572b9a9cd3ad2b642f1e 744 Pfam PF14490 Helix-hairpin-helix containing domain 148 236 2.3E-30 T 28-03-2018 IPR029493 RecD helicase-like helix-hairpin-helix domain CIG75_RS02270 e4831b7299c1572b9a9cd3ad2b642f1e 744 Gene3D G3DSA:1.10.150.20 104 131 3.4E-8 T 28-03-2018 CIG75_RS02270 e4831b7299c1572b9a9cd3ad2b642f1e 744 SUPERFAMILY SSF52540 446 513 5.4E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS02270 e4831b7299c1572b9a9cd3ad2b642f1e 744 SUPERFAMILY SSF52540 554 732 5.4E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS04485 254ec8290a81437b085955a9a828d054 439 Gene3D G3DSA:2.40.50.140 1 59 1.3E-19 T 28-03-2018 CIG75_RS04485 254ec8290a81437b085955a9a828d054 439 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 367 398 - T 28-03-2018 IPR030390 RNA methyltransferase TrmA, active site CIG75_RS04485 254ec8290a81437b085955a9a828d054 439 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 2 428 1.5E-158 T 28-03-2018 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 CIG75_RS04485 254ec8290a81437b085955a9a828d054 439 Pfam PF01938 TRAM domain 4 44 1.9E-5 T 28-03-2018 IPR002792 TRAM domain CIG75_RS04485 254ec8290a81437b085955a9a828d054 439 SUPERFAMILY SSF50249 1 50 6.85E-10 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CIG75_RS04485 254ec8290a81437b085955a9a828d054 439 Gene3D G3DSA:3.40.50.150 60 124 4.1E-11 T 28-03-2018 CIG75_RS04485 254ec8290a81437b085955a9a828d054 439 Gene3D G3DSA:3.40.50.150 183 434 8.5E-54 T 28-03-2018 CIG75_RS04485 254ec8290a81437b085955a9a828d054 439 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 74 435 4.8E-21 T 28-03-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 CIG75_RS04485 254ec8290a81437b085955a9a828d054 439 SUPERFAMILY SSF53335 52 435 1.88E-86 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CIG75_RS04485 254ec8290a81437b085955a9a828d054 439 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 418 428 - T 28-03-2018 IPR030391 RNA methyltransferase TrmA, conserved site CIG75_RS05140 e963c670785dbe74d86945d23e41b4f3 572 ProSitePatterns PS00211 ABC transporters family signature. 447 461 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS05140 e963c670785dbe74d86945d23e41b4f3 572 SUPERFAMILY SSF52540 307 537 4.26E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS05140 e963c670785dbe74d86945d23e41b4f3 572 Pfam PF00005 ABC transporter 23 174 2.9E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS05140 e963c670785dbe74d86945d23e41b4f3 572 Pfam PF00005 ABC transporter 327 474 4.3E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS05140 e963c670785dbe74d86945d23e41b4f3 572 SMART SM00382 336 539 1.9E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS05140 e963c670785dbe74d86945d23e41b4f3 572 SMART SM00382 32 231 3.1E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS05140 e963c670785dbe74d86945d23e41b4f3 572 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS05140 e963c670785dbe74d86945d23e41b4f3 572 Gene3D G3DSA:3.40.50.300 300 548 1.7E-62 T 28-03-2018 CIG75_RS05140 e963c670785dbe74d86945d23e41b4f3 572 Gene3D G3DSA:3.40.50.300 1 251 4.1E-62 T 28-03-2018 CIG75_RS05140 e963c670785dbe74d86945d23e41b4f3 572 SUPERFAMILY SSF52540 6 235 2.6E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS09445 4d496b8eaa4cb7f4d987cc0847c9e34e 450 Gene3D G3DSA:3.40.390.10 42 202 3.9E-4 T 28-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 CIG75_RS13830 c091ceff32056c480f5e5225d31c19ee 437 SMART SM00228 123 199 5.9E-6 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CIG75_RS13830 c091ceff32056c480f5e5225d31c19ee 437 Pfam PF05580 SpoIVB peptidase S55 216 424 2.3E-87 T 28-03-2018 IPR008763 Peptidase S55, SpoIVB CIG75_RS13830 c091ceff32056c480f5e5225d31c19ee 437 TIGRFAM TIGR02860 spore_IV_B: stage IV sporulation protein B 5 429 2.4E-156 T 28-03-2018 IPR014219 Peptidase S55, sporulation stage IV, protein B CIG75_RS13830 c091ceff32056c480f5e5225d31c19ee 437 Gene3D G3DSA:2.30.42.10 108 230 2.6E-17 T 28-03-2018 CIG75_RS13830 c091ceff32056c480f5e5225d31c19ee 437 SUPERFAMILY SSF50156 150 234 7.05E-11 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CIG75_RS13830 c091ceff32056c480f5e5225d31c19ee 437 Pfam PF13180 PDZ domain 147 207 3.3E-10 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CIG75_RS13830 c091ceff32056c480f5e5225d31c19ee 437 SUPERFAMILY SSF50494 357 421 3.1E-5 T 28-03-2018 IPR009003 Peptidase S1, PA clan CIG75_RS18690 2670396a794452976b6e30c4cf71bb50 430 Gene3D G3DSA:1.20.200.10 93 348 1.9E-78 T 28-03-2018 CIG75_RS18690 2670396a794452976b6e30c4cf71bb50 430 Pfam PF10397 Adenylosuccinate lyase C-terminus 350 427 5.5E-26 T 28-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CIG75_RS18690 2670396a794452976b6e30c4cf71bb50 430 ProSitePatterns PS00163 Fumarate lyases signature. 261 270 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 CIG75_RS18690 2670396a794452976b6e30c4cf71bb50 430 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 2 428 2.5E-173 T 28-03-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CIG75_RS18690 2670396a794452976b6e30c4cf71bb50 430 SUPERFAMILY SSF48557 3 427 5.65E-137 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 CIG75_RS18690 2670396a794452976b6e30c4cf71bb50 430 PRINTS PR00145 Argininosuccinate lyase family signature 87 109 5.6E-10 T 28-03-2018 CIG75_RS18690 2670396a794452976b6e30c4cf71bb50 430 PRINTS PR00145 Argininosuccinate lyase family signature 261 277 5.6E-10 T 28-03-2018 CIG75_RS18690 2670396a794452976b6e30c4cf71bb50 430 PRINTS PR00145 Argininosuccinate lyase family signature 216 240 5.6E-10 T 28-03-2018 CIG75_RS18690 2670396a794452976b6e30c4cf71bb50 430 PRINTS PR00145 Argininosuccinate lyase family signature 128 148 5.6E-10 T 28-03-2018 CIG75_RS18690 2670396a794452976b6e30c4cf71bb50 430 SMART SM00998 349 429 1.8E-41 T 28-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CIG75_RS18690 2670396a794452976b6e30c4cf71bb50 430 Gene3D G3DSA:1.10.40.30 349 428 4.1E-27 T 28-03-2018 CIG75_RS18690 2670396a794452976b6e30c4cf71bb50 430 Pfam PF00206 Lyase 8 282 1.4E-67 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal CIG75_RS18690 2670396a794452976b6e30c4cf71bb50 430 PRINTS PR00149 Fumarate lyase superfamily signature 88 106 2.2E-26 T 28-03-2018 IPR000362 Fumarate lyase family CIG75_RS18690 2670396a794452976b6e30c4cf71bb50 430 PRINTS PR00149 Fumarate lyase superfamily signature 133 151 2.2E-26 T 28-03-2018 IPR000362 Fumarate lyase family CIG75_RS18690 2670396a794452976b6e30c4cf71bb50 430 PRINTS PR00149 Fumarate lyase superfamily signature 216 243 2.2E-26 T 28-03-2018 IPR000362 Fumarate lyase family CIG75_RS18690 2670396a794452976b6e30c4cf71bb50 430 PRINTS PR00149 Fumarate lyase superfamily signature 261 277 2.2E-26 T 28-03-2018 IPR000362 Fumarate lyase family CIG75_RS18690 2670396a794452976b6e30c4cf71bb50 430 Gene3D G3DSA:1.10.275.10 2 92 4.0E-21 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal CIG75_RS01065 164fefbbd222cb6eab72cdf7dea152f9 253 SMART SM00849 22 231 1.5E-28 T 28-03-2018 IPR001279 Metallo-beta-lactamase CIG75_RS01065 164fefbbd222cb6eab72cdf7dea152f9 253 Pfam PF00753 Metallo-beta-lactamase superfamily 26 231 2.4E-21 T 28-03-2018 IPR001279 Metallo-beta-lactamase CIG75_RS01065 164fefbbd222cb6eab72cdf7dea152f9 253 SUPERFAMILY SSF56281 5 246 2.49E-47 T 28-03-2018 IPR001279 Metallo-beta-lactamase CIG75_RS01065 164fefbbd222cb6eab72cdf7dea152f9 253 Gene3D G3DSA:3.60.15.10 9 252 5.6E-36 T 28-03-2018 IPR001279 Metallo-beta-lactamase CIG75_RS02325 b42228c4db4dfb6f218f906b52444610 280 Gene3D G3DSA:3.30.1180.10 153 280 6.4E-42 T 28-03-2018 CIG75_RS02325 b42228c4db4dfb6f218f906b52444610 280 Gene3D G3DSA:3.40.50.10170 1 152 8.6E-52 T 28-03-2018 CIG75_RS02325 b42228c4db4dfb6f218f906b52444610 280 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 4 277 2.7E-106 T 28-03-2018 IPR003797 DegV CIG75_RS02325 b42228c4db4dfb6f218f906b52444610 280 SUPERFAMILY SSF82549 1 277 5.23E-93 T 28-03-2018 CIG75_RS02325 b42228c4db4dfb6f218f906b52444610 280 Pfam PF02645 Uncharacterised protein, DegV family COG1307 3 277 6.6E-97 T 28-03-2018 IPR003797 DegV CIG75_RS09570 3fbef3ac2cfed93a3849710910f93caa 299 Gene3D G3DSA:3.40.50.720 2 185 5.2E-47 T 28-03-2018 CIG75_RS09570 3fbef3ac2cfed93a3849710910f93caa 299 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 5 182 5.8E-47 T 28-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CIG75_RS09570 3fbef3ac2cfed93a3849710910f93caa 299 PIRSF PIRSF000105 1 299 9.3E-88 T 28-03-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 CIG75_RS09570 3fbef3ac2cfed93a3849710910f93caa 299 Gene3D G3DSA:1.10.1040.10 186 291 4.7E-20 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CIG75_RS09570 3fbef3ac2cfed93a3849710910f93caa 299 SUPERFAMILY SSF51735 1 183 4.28E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS09570 3fbef3ac2cfed93a3849710910f93caa 299 SUPERFAMILY SSF48179 187 295 2.98E-19 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CIG75_RS09570 3fbef3ac2cfed93a3849710910f93caa 299 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 188 286 5.1E-17 T 28-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CIG75_RS05735 04f6dbac5c5f8908a6eb5ffa6ae0f38c 433 Gene3D G3DSA:1.25.40.10 209 277 2.9E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS05735 04f6dbac5c5f8908a6eb5ffa6ae0f38c 433 Gene3D G3DSA:1.10.260.40 5 83 4.7E-16 T 28-03-2018 CIG75_RS05735 04f6dbac5c5f8908a6eb5ffa6ae0f38c 433 SUPERFAMILY SSF48452 186 345 4.07E-23 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS05735 04f6dbac5c5f8908a6eb5ffa6ae0f38c 433 Gene3D G3DSA:1.25.40.10 278 378 1.5E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS05735 04f6dbac5c5f8908a6eb5ffa6ae0f38c 433 Pfam PF13424 Tetratricopeptide repeat 114 177 9.0E-10 T 28-03-2018 CIG75_RS05735 04f6dbac5c5f8908a6eb5ffa6ae0f38c 433 Pfam PF13424 Tetratricopeptide repeat 195 266 2.1E-10 T 28-03-2018 CIG75_RS05735 04f6dbac5c5f8908a6eb5ffa6ae0f38c 433 SUPERFAMILY SSF47413 5 68 1.15E-14 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CIG75_RS05735 04f6dbac5c5f8908a6eb5ffa6ae0f38c 433 Pfam PF12844 Helix-turn-helix domain 9 68 8.1E-11 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS05735 04f6dbac5c5f8908a6eb5ffa6ae0f38c 433 Gene3D G3DSA:1.25.40.10 150 208 3.6E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS05735 04f6dbac5c5f8908a6eb5ffa6ae0f38c 433 Gene3D G3DSA:1.10.287.1110 132 149 1.5E-4 T 28-03-2018 CIG75_RS05735 04f6dbac5c5f8908a6eb5ffa6ae0f38c 433 SUPERFAMILY SSF48452 77 222 2.91E-16 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS05735 04f6dbac5c5f8908a6eb5ffa6ae0f38c 433 Gene3D G3DSA:1.25.40.10 379 422 0.0025 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS05735 04f6dbac5c5f8908a6eb5ffa6ae0f38c 433 SMART SM00028 314 347 9.1 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS05735 04f6dbac5c5f8908a6eb5ffa6ae0f38c 433 SMART SM00028 352 385 4.5 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS05735 04f6dbac5c5f8908a6eb5ffa6ae0f38c 433 SMART SM00028 234 267 0.79 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS05735 04f6dbac5c5f8908a6eb5ffa6ae0f38c 433 SMART SM00028 274 307 210.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS05735 04f6dbac5c5f8908a6eb5ffa6ae0f38c 433 SMART SM00028 112 145 9.2E-4 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS05735 04f6dbac5c5f8908a6eb5ffa6ae0f38c 433 SMART SM00028 152 185 73.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS05735 04f6dbac5c5f8908a6eb5ffa6ae0f38c 433 SMART SM00028 194 227 9.2E-4 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS05735 04f6dbac5c5f8908a6eb5ffa6ae0f38c 433 Gene3D G3DSA:1.25.40.10 84 131 8.3E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS05735 04f6dbac5c5f8908a6eb5ffa6ae0f38c 433 SMART SM00530 11 65 9.9E-12 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS06640 ef668c72b8ae5bb42178ceb896f6fa67 1383 Gene3D G3DSA:1.10.1200.10 573 684 3.5E-14 T 28-03-2018 CIG75_RS06640 ef668c72b8ae5bb42178ceb896f6fa67 1383 Gene3D G3DSA:3.40.50.980 8 172 2.1E-31 T 28-03-2018 CIG75_RS06640 ef668c72b8ae5bb42178ceb896f6fa67 1383 Pfam PF00668 Condensation domain 701 1158 1.0E-111 T 28-03-2018 IPR001242 Condensation domain CIG75_RS06640 ef668c72b8ae5bb42178ceb896f6fa67 1383 SMART SM01294 613 679 0.0042 T 28-03-2018 CIG75_RS06640 ef668c72b8ae5bb42178ceb896f6fa67 1383 Pfam PF00550 Phosphopantetheine attachment site 618 677 5.3E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS06640 ef668c72b8ae5bb42178ceb896f6fa67 1383 Gene3D G3DSA:3.30.300.30 457 562 2.6E-16 T 28-03-2018 CIG75_RS06640 ef668c72b8ae5bb42178ceb896f6fa67 1383 ProSitePatterns PS00455 Putative AMP-binding domain signature. 168 179 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS06640 ef668c72b8ae5bb42178ceb896f6fa67 1383 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1320 1331 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS06640 ef668c72b8ae5bb42178ceb896f6fa67 1383 Pfam PF00501 AMP-binding enzyme 17 462 2.6E-73 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS06640 ef668c72b8ae5bb42178ceb896f6fa67 1383 Pfam PF00501 AMP-binding enzyme 1179 1383 2.9E-55 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS06640 ef668c72b8ae5bb42178ceb896f6fa67 1383 SUPERFAMILY SSF52777 705 879 1.22E-47 T 28-03-2018 CIG75_RS06640 ef668c72b8ae5bb42178ceb896f6fa67 1383 SUPERFAMILY SSF47336 611 714 1.7E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS06640 ef668c72b8ae5bb42178ceb896f6fa67 1383 SUPERFAMILY SSF56801 9 580 8.9E-100 T 28-03-2018 CIG75_RS06640 ef668c72b8ae5bb42178ceb896f6fa67 1383 Gene3D G3DSA:3.40.50.980 1326 1383 1.4E-16 T 28-03-2018 CIG75_RS06640 ef668c72b8ae5bb42178ceb896f6fa67 1383 Gene3D G3DSA:3.40.50.980 173 344 1.4E-27 T 28-03-2018 CIG75_RS06640 ef668c72b8ae5bb42178ceb896f6fa67 1383 PRINTS PR00154 AMP-binding signature 1315 1326 2.9E-5 T 28-03-2018 IPR020459 AMP-binding CIG75_RS06640 ef668c72b8ae5bb42178ceb896f6fa67 1383 PRINTS PR00154 AMP-binding signature 1327 1335 2.9E-5 T 28-03-2018 IPR020459 AMP-binding CIG75_RS06640 ef668c72b8ae5bb42178ceb896f6fa67 1383 Gene3D G3DSA:3.30.559.10 685 882 9.5E-43 T 28-03-2018 CIG75_RS06640 ef668c72b8ae5bb42178ceb896f6fa67 1383 Gene3D G3DSA:3.40.50.980 1170 1325 9.3E-50 T 28-03-2018 CIG75_RS06640 ef668c72b8ae5bb42178ceb896f6fa67 1383 SMART SM00823 Phosphopantetheine attachment site 612 683 4.9E-14 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS06640 ef668c72b8ae5bb42178ceb896f6fa67 1383 Gene3D G3DSA:2.30.38.10 378 455 1.3E-15 T 28-03-2018 CIG75_RS06640 ef668c72b8ae5bb42178ceb896f6fa67 1383 SUPERFAMILY SSF56801 1136 1382 4.84E-67 T 28-03-2018 CIG75_RS06640 ef668c72b8ae5bb42178ceb896f6fa67 1383 SUPERFAMILY SSF52777 890 1165 4.78E-60 T 28-03-2018 CIG75_RS06830 22d141cba850b8fac598f686702f1f96 489 Pfam PF02517 CAAX protease self-immunity 359 453 8.5E-10 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CIG75_RS01770 e9c7ec1186685dc9571310cb0323da0a 437 SUPERFAMILY SSF52540 96 374 1.06E-66 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS01770 e9c7ec1186685dc9571310cb0323da0a 437 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 420 215.643 T 28-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 CIG75_RS01770 e9c7ec1186685dc9571310cb0323da0a 437 Pfam PF07497 Rho termination factor, RNA-binding domain 60 131 6.8E-32 T 28-03-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 CIG75_RS01770 e9c7ec1186685dc9571310cb0323da0a 437 SMART SM00382 173 358 7.0E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS01770 e9c7ec1186685dc9571310cb0323da0a 437 SUPERFAMILY SSF68912 10 54 6.67E-10 T 28-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 CIG75_RS01770 e9c7ec1186685dc9571310cb0323da0a 437 TIGRFAM TIGR00767 rho: transcription termination factor Rho 11 417 1.4E-198 T 28-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 CIG75_RS01770 e9c7ec1186685dc9571310cb0323da0a 437 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 162 366 2.9E-18 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CIG75_RS01770 e9c7ec1186685dc9571310cb0323da0a 437 Gene3D G3DSA:1.10.720.10 9 51 7.4E-14 T 28-03-2018 CIG75_RS01770 e9c7ec1186685dc9571310cb0323da0a 437 Gene3D G3DSA:3.40.50.300 116 370 1.5E-50 T 28-03-2018 CIG75_RS01770 e9c7ec1186685dc9571310cb0323da0a 437 SUPERFAMILY SSF50249 57 131 8.57E-25 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CIG75_RS01770 e9c7ec1186685dc9571310cb0323da0a 437 Gene3D G3DSA:2.40.50.140 57 115 3.0E-29 T 28-03-2018 CIG75_RS01770 e9c7ec1186685dc9571310cb0323da0a 437 SMART SM00357 60 124 4.7E-20 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 CIG75_RS01770 e9c7ec1186685dc9571310cb0323da0a 437 Pfam PF07498 Rho termination factor, N-terminal domain 15 55 2.6E-13 T 28-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 CIG75_RS01770 e9c7ec1186685dc9571310cb0323da0a 437 SMART SM00959 13 54 1.7E-12 T 28-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 CIG75_RS01570 e841a199645ac02fa9b94e7f542a3313 397 Pfam PF10720 Protein of unknown function (DUF2515) 61 387 5.6E-110 T 28-03-2018 IPR019658 Protein of unknown function DUF2515 CIG75_RS14520 c68745dea0c50d5090a1f2858f5210e9 284 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 71 265 2.6E-26 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CIG75_RS14520 c68745dea0c50d5090a1f2858f5210e9 284 SUPERFAMILY SSF52266 66 274 4.09E-37 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CIG75_RS14520 c68745dea0c50d5090a1f2858f5210e9 284 Gene3D G3DSA:3.40.50.1110 34 274 3.0E-37 T 28-03-2018 CIG75_RS06645 df52148eabe5857f21653f769822f194 397 SUPERFAMILY SSF47336 288 361 5.76E-21 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS06645 df52148eabe5857f21653f769822f194 397 Pfam PF00550 Phosphopantetheine attachment site 297 360 1.4E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS06645 df52148eabe5857f21653f769822f194 397 SMART SM00823 Phosphopantetheine attachment site 296 365 0.0013 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS06645 df52148eabe5857f21653f769822f194 397 Pfam PF00501 AMP-binding enzyme 2 186 1.1E-44 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS06645 df52148eabe5857f21653f769822f194 397 SUPERFAMILY SSF56801 12 309 8.37E-93 T 28-03-2018 CIG75_RS06645 df52148eabe5857f21653f769822f194 397 Gene3D G3DSA:1.10.1200.10 300 374 1.8E-22 T 28-03-2018 CIG75_RS06645 df52148eabe5857f21653f769822f194 397 Pfam PF13193 AMP-binding enzyme C-terminal domain 194 269 5.8E-12 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS06645 df52148eabe5857f21653f769822f194 397 Gene3D G3DSA:3.40.50.980 2 97 2.6E-15 T 28-03-2018 CIG75_RS06645 df52148eabe5857f21653f769822f194 397 Gene3D G3DSA:2.30.38.10 98 179 2.3E-25 T 28-03-2018 CIG75_RS06645 df52148eabe5857f21653f769822f194 397 Gene3D G3DSA:3.30.300.30 181 299 5.6E-42 T 28-03-2018 CIG75_RS03160 99cbe610bfe803b10ff957e3129f32aa 441 Pfam PF10076 Uncharacterised protein conserved in bacteria (DUF2313) 14 161 2.5E-24 T 28-03-2018 IPR018755 Bacteriophage Mu-like, Gp48 CIG75_RS20115 53a94c55ae4106a144a55fb864cd3bb9 298 Pfam PF01430 Hsp33 protein 3 284 5.2E-86 T 28-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 CIG75_RS20115 53a94c55ae4106a144a55fb864cd3bb9 298 SUPERFAMILY SSF118352 237 292 3.27E-18 T 28-03-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 CIG75_RS20115 53a94c55ae4106a144a55fb864cd3bb9 298 Gene3D G3DSA:3.55.30.10 2 238 1.1E-71 T 28-03-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 CIG75_RS20115 53a94c55ae4106a144a55fb864cd3bb9 298 Gene3D G3DSA:3.90.1280.10 239 292 4.2E-22 T 28-03-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 CIG75_RS20115 53a94c55ae4106a144a55fb864cd3bb9 298 PIRSF PIRSF005261 1 296 9.9E-72 T 28-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 CIG75_RS20115 53a94c55ae4106a144a55fb864cd3bb9 298 SUPERFAMILY SSF64397 2 245 4.45E-72 T 28-03-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 CIG75_RS20115 53a94c55ae4106a144a55fb864cd3bb9 298 Hamap MF_00117 33 kDa chaperonin [hslO]. 2 295 37.702 T 28-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 CIG75_RS13845 1d5cd253cfbd28b281bc0e2ceeee33d8 285 SUPERFAMILY SSF111331 4 282 2.75E-80 T 28-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain CIG75_RS13845 1d5cd253cfbd28b281bc0e2ceeee33d8 285 Pfam PF01513 ATP-NAD kinase 7 267 1.6E-59 T 28-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CIG75_RS13845 1d5cd253cfbd28b281bc0e2ceeee33d8 285 Gene3D G3DSA:3.40.50.10330 1 136 2.5E-32 T 28-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 CIG75_RS13845 1d5cd253cfbd28b281bc0e2ceeee33d8 285 Gene3D G3DSA:2.60.200.30 137 260 1.9E-39 T 28-03-2018 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CIG75_RS13845 1d5cd253cfbd28b281bc0e2ceeee33d8 285 Hamap MF_00361 NAD kinase [nadK]. 2 283 32.023 T 28-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CIG75_RS17660 7cf3a8247ce98f2764537ed2f8f9f127 249 SMART SM00646 134 243 7.8E-31 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CIG75_RS17660 7cf3a8247ce98f2764537ed2f8f9f127 249 Gene3D G3DSA:3.40.630.40 70 246 1.9E-53 T 28-03-2018 CIG75_RS17660 7cf3a8247ce98f2764537ed2f8f9f127 249 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 75 243 5.5E-47 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CIG75_RS17660 7cf3a8247ce98f2764537ed2f8f9f127 249 SUPERFAMILY SSF53187 74 243 9.73E-47 T 28-03-2018 CIG75_RS12195 eec33f5fecff4d75b04e8a110cd515a1 122 Pfam PF02021 Uncharacterised protein family UPF0102 12 103 1.9E-28 T 28-03-2018 IPR003509 Uncharacterised protein family UPF0102 CIG75_RS12195 eec33f5fecff4d75b04e8a110cd515a1 122 Gene3D G3DSA:3.40.1350.10 11 122 1.3E-34 T 28-03-2018 CIG75_RS12195 eec33f5fecff4d75b04e8a110cd515a1 122 Hamap MF_00048 UPF0102 protein YraN [yraN]. 5 116 22.357 T 28-03-2018 IPR003509 Uncharacterised protein family UPF0102 CIG75_RS12195 eec33f5fecff4d75b04e8a110cd515a1 122 TIGRFAM TIGR00252 TIGR00252: TIGR00252 family protein 5 107 1.5E-25 T 28-03-2018 IPR003509 Uncharacterised protein family UPF0102 CIG75_RS12195 eec33f5fecff4d75b04e8a110cd515a1 122 SUPERFAMILY SSF52980 6 109 4.93E-21 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CIG75_RS15450 c37b80865c2c0fea1885c5163f1302cd 259 Gene3D G3DSA:3.40.190.10 33 141 1.7E-33 T 28-03-2018 CIG75_RS15450 c37b80865c2c0fea1885c5163f1302cd 259 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 41 257 6.6E-61 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CIG75_RS15450 c37b80865c2c0fea1885c5163f1302cd 259 SUPERFAMILY SSF53850 1 257 1.71E-67 T 28-03-2018 CIG75_RS15450 c37b80865c2c0fea1885c5163f1302cd 259 SMART SM00079 40 258 8.1E-4 T 28-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 CIG75_RS15450 c37b80865c2c0fea1885c5163f1302cd 259 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 65 78 - T 28-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 CIG75_RS15450 c37b80865c2c0fea1885c5163f1302cd 259 SMART SM00062 40 259 4.3E-64 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CIG75_RS15450 c37b80865c2c0fea1885c5163f1302cd 259 Gene3D G3DSA:3.40.190.10 142 220 7.8E-22 T 28-03-2018 CIG75_RS14055 3dba8014eda03fd050985a2141a79eb3 286 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 9 282 9.1E-90 T 28-03-2018 IPR003797 DegV CIG75_RS14055 3dba8014eda03fd050985a2141a79eb3 286 Gene3D G3DSA:3.30.1180.10 159 284 4.2E-27 T 28-03-2018 CIG75_RS14055 3dba8014eda03fd050985a2141a79eb3 286 Gene3D G3DSA:3.40.50.10440 59 156 2.1E-33 T 28-03-2018 CIG75_RS14055 3dba8014eda03fd050985a2141a79eb3 286 Gene3D G3DSA:2.20.28.50 39 58 9.6E-15 T 28-03-2018 CIG75_RS14055 3dba8014eda03fd050985a2141a79eb3 286 Pfam PF02645 Uncharacterised protein, DegV family COG1307 8 284 5.1E-79 T 28-03-2018 IPR003797 DegV CIG75_RS14055 3dba8014eda03fd050985a2141a79eb3 286 SUPERFAMILY SSF82549 9 284 7.59E-80 T 28-03-2018 CIG75_RS14055 3dba8014eda03fd050985a2141a79eb3 286 Gene3D G3DSA:3.40.50.10440 6 38 0.06 T 28-03-2018 CIG75_RS04285 3cd29b2af2f64116ffefef882cdec077 152 Gene3D G3DSA:1.10.10.10 8 112 2.0E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS04285 3cd29b2af2f64116ffefef882cdec077 152 SMART SM00347 29 129 5.5E-23 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CIG75_RS04285 3cd29b2af2f64116ffefef882cdec077 152 SUPERFAMILY SSF46785 16 146 1.06E-32 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS04285 3cd29b2af2f64116ffefef882cdec077 152 Gene3D G3DSA:1.10.287.100 113 146 6.6E-9 T 28-03-2018 CIG75_RS04285 3cd29b2af2f64116ffefef882cdec077 152 PRINTS PR00598 Bacterial regulatory protein MarR family signature 119 139 4.4E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CIG75_RS04285 3cd29b2af2f64116ffefef882cdec077 152 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 105 4.4E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CIG75_RS04285 3cd29b2af2f64116ffefef882cdec077 152 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 85 4.4E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CIG75_RS04285 3cd29b2af2f64116ffefef882cdec077 152 Pfam PF01047 MarR family 36 94 1.7E-14 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CIG75_RS07055 8a88479d6868af1a0cc4510544851206 97 SUPERFAMILY SSF75471 1 95 5.49E-30 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CIG75_RS07055 8a88479d6868af1a0cc4510544851206 97 SMART SM01103 2 85 2.5E-40 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CIG75_RS07055 8a88479d6868af1a0cc4510544851206 97 Pfam PF01985 CRS1 / YhbY (CRM) domain 2 85 5.6E-23 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CIG75_RS07055 8a88479d6868af1a0cc4510544851206 97 TIGRFAM TIGR00253 RNA_bind_YhbY: putative RNA-binding protein, YhbY family 2 97 1.1E-38 T 28-03-2018 IPR017924 RNA-binding protein YhbY GO:0003723 CIG75_RS07055 8a88479d6868af1a0cc4510544851206 97 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 8 96 3.0E-30 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CIG75_RS07055 8a88479d6868af1a0cc4510544851206 97 Gene3D G3DSA:3.30.110.60 1 97 1.2E-28 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CIG75_RS05035 639cbf634604e8b32277428cac18cdd7 459 Gene3D G3DSA:1.10.287.130 236 306 4.2E-14 T 28-03-2018 CIG75_RS05035 639cbf634604e8b32277428cac18cdd7 459 SUPERFAMILY SSF55874 301 458 4.19E-31 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS05035 639cbf634604e8b32277428cac18cdd7 459 SUPERFAMILY SSF158472 193 242 2.88E-6 T 28-03-2018 CIG75_RS05035 639cbf634604e8b32277428cac18cdd7 459 Pfam PF00672 HAMP domain 193 241 8.1E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CIG75_RS05035 639cbf634604e8b32277428cac18cdd7 459 SMART SM00304 193 245 3.2E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CIG75_RS05035 639cbf634604e8b32277428cac18cdd7 459 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 358 458 5.7E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS05035 639cbf634604e8b32277428cac18cdd7 459 Gene3D G3DSA:3.30.565.10 307 459 1.5E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS05035 639cbf634604e8b32277428cac18cdd7 459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 409 419 5.9E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS05035 639cbf634604e8b32277428cac18cdd7 459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 392 406 5.9E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS05035 639cbf634604e8b32277428cac18cdd7 459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 420 438 5.9E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS05035 639cbf634604e8b32277428cac18cdd7 459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 444 457 5.9E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS05035 639cbf634604e8b32277428cac18cdd7 459 SUPERFAMILY SSF47384 231 310 1.08E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CIG75_RS05035 639cbf634604e8b32277428cac18cdd7 459 SMART SM00388 246 312 7.9E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CIG75_RS05035 639cbf634604e8b32277428cac18cdd7 459 Pfam PF00512 His Kinase A (phospho-acceptor) domain 246 311 1.0E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CIG75_RS05035 639cbf634604e8b32277428cac18cdd7 459 SMART SM00387 357 459 1.1E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS11655 d63ab84bda562e357e691e8152b3019f 127 Gene3D G3DSA:3.10.490.10 1 127 5.9E-27 T 28-03-2018 CIG75_RS11655 d63ab84bda562e357e691e8152b3019f 127 Pfam PF06094 Gamma-glutamyl cyclotransferase, AIG2-like 4 121 3.7E-23 T 28-03-2018 IPR009288 Gamma-glutamylcyclotransferase, AIG2-like CIG75_RS11655 d63ab84bda562e357e691e8152b3019f 127 SUPERFAMILY SSF110857 1 125 4.32E-24 T 28-03-2018 IPR013024 Gamma-glutamyl cyclotransferase-like CIG75_RS12430 34c51abd9d5cc168f8e9a2581ad678ff 70 Pfam PF09388 Spo0E like sporulation regulatory protein 7 48 6.4E-13 T 28-03-2018 IPR018540 Aspartyl-phosphate phosphatase Spo0E-like GO:0043937 CIG75_RS12430 34c51abd9d5cc168f8e9a2581ad678ff 70 SUPERFAMILY SSF140500 1 53 1.1E-10 T 28-03-2018 CIG75_RS04710 fe6c475c6d8f2d204e66250faeb8c716 631 SUPERFAMILY SSF69318 341 616 3.14E-27 T 28-03-2018 CIG75_RS04710 fe6c475c6d8f2d204e66250faeb8c716 631 SUPERFAMILY SSF88713 44 261 2.07E-6 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CIG75_RS04710 fe6c475c6d8f2d204e66250faeb8c716 631 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 500 562 2.1E-8 T 28-03-2018 CIG75_RS04710 fe6c475c6d8f2d204e66250faeb8c716 631 Gene3D G3DSA:2.130.10.130 473 623 4.2E-17 T 28-03-2018 CIG75_RS04710 fe6c475c6d8f2d204e66250faeb8c716 631 Gene3D G3DSA:2.130.10.130 274 431 2.2E-5 T 28-03-2018 CIG75_RS04710 fe6c475c6d8f2d204e66250faeb8c716 631 Gene3D G3DSA:3.20.20.370 24 222 3.9E-4 T 28-03-2018 CIG75_RS04710 fe6c475c6d8f2d204e66250faeb8c716 631 Pfam PF10096 Uncharacterized protein conserved in bacteria (DUF2334) 35 281 1.0E-41 T 28-03-2018 IPR018763 Protein of unknown function DUF2334 CIG75_RS05845 5350f4e38f6b12d609b678f9e007af03 128 Gene3D G3DSA:3.60.90.10 1 125 8.0E-41 T 28-03-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 CIG75_RS05845 5350f4e38f6b12d609b678f9e007af03 128 Hamap MF_00464 S-adenosylmethionine decarboxylase proenzyme [speH]. 1 117 32.158 T 28-03-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 CIG75_RS05845 5350f4e38f6b12d609b678f9e007af03 128 Pfam PF02675 S-adenosylmethionine decarboxylase 7 112 1.2E-36 T 28-03-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 CIG75_RS05845 5350f4e38f6b12d609b678f9e007af03 128 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 3 113 5.1E-41 T 28-03-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 CIG75_RS05845 5350f4e38f6b12d609b678f9e007af03 128 SUPERFAMILY SSF56276 3 114 5.89E-41 T 28-03-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 CIG75_RS00010 45628f7ff6687d2422193aa4f6bd446a 110 Gene3D G3DSA:1.20.5.340 2 82 5.4E-6 T 28-03-2018 CIG75_RS00010 45628f7ff6687d2422193aa4f6bd446a 110 SUPERFAMILY SSF58026 23 55 7.32E-5 T 28-03-2018 CIG75_RS00010 45628f7ff6687d2422193aa4f6bd446a 110 PIRSF PIRSF021439 1 110 2.4E-40 T 28-03-2018 IPR010377 Initiation control protein YabA GO:0006260 CIG75_RS00010 45628f7ff6687d2422193aa4f6bd446a 110 Pfam PF06156 Initiation control protein YabA 2 106 1.2E-37 T 28-03-2018 IPR010377 Initiation control protein YabA GO:0006260 CIG75_RS00010 45628f7ff6687d2422193aa4f6bd446a 110 Hamap MF_01159 Initiation-control protein YabA. 1 110 23.68 T 28-03-2018 IPR010377 Initiation control protein YabA GO:0006260 CIG75_RS12150 18ae5b1cd12996d6ca7c6e4a3437ba4d 147 Gene3D G3DSA:3.90.420.10 1 145 7.1E-11 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CIG75_RS12150 18ae5b1cd12996d6ca7c6e4a3437ba4d 147 Pfam PF00174 Oxidoreductase molybdopterin binding domain 48 131 1.3E-6 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CIG75_RS12150 18ae5b1cd12996d6ca7c6e4a3437ba4d 147 SUPERFAMILY SSF56524 4 138 3.92E-14 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CIG75_RS17075 a8b5096854d5a8ff0d1653a93b25ab3b 395 Pfam PF00162 Phosphoglycerate kinase 6 384 1.1E-162 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS17075 a8b5096854d5a8ff0d1653a93b25ab3b 395 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 15 25 - T 28-03-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS17075 a8b5096854d5a8ff0d1653a93b25ab3b 395 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 8 394 42.615 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS17075 a8b5096854d5a8ff0d1653a93b25ab3b 395 PIRSF PIRSF000724 1 395 4.8E-156 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS17075 a8b5096854d5a8ff0d1653a93b25ab3b 395 Gene3D G3DSA:3.40.50.1260 179 382 3.7E-82 T 28-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS17075 a8b5096854d5a8ff0d1653a93b25ab3b 395 PRINTS PR00477 Phosphoglycerate kinase family signature 109 124 1.1E-99 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS17075 a8b5096854d5a8ff0d1653a93b25ab3b 395 PRINTS PR00477 Phosphoglycerate kinase family signature 314 339 1.1E-99 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS17075 a8b5096854d5a8ff0d1653a93b25ab3b 395 PRINTS PR00477 Phosphoglycerate kinase family signature 31 53 1.1E-99 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS17075 a8b5096854d5a8ff0d1653a93b25ab3b 395 PRINTS PR00477 Phosphoglycerate kinase family signature 347 358 1.1E-99 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS17075 a8b5096854d5a8ff0d1653a93b25ab3b 395 PRINTS PR00477 Phosphoglycerate kinase family signature 137 159 1.1E-99 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS17075 a8b5096854d5a8ff0d1653a93b25ab3b 395 PRINTS PR00477 Phosphoglycerate kinase family signature 167 189 1.1E-99 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS17075 a8b5096854d5a8ff0d1653a93b25ab3b 395 PRINTS PR00477 Phosphoglycerate kinase family signature 370 387 1.1E-99 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS17075 a8b5096854d5a8ff0d1653a93b25ab3b 395 PRINTS PR00477 Phosphoglycerate kinase family signature 10 26 1.1E-99 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS17075 a8b5096854d5a8ff0d1653a93b25ab3b 395 PRINTS PR00477 Phosphoglycerate kinase family signature 190 209 1.1E-99 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS17075 a8b5096854d5a8ff0d1653a93b25ab3b 395 Gene3D G3DSA:3.40.50.1260 3 178 4.7E-78 T 28-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS17075 a8b5096854d5a8ff0d1653a93b25ab3b 395 SUPERFAMILY SSF53748 1 394 3.18E-158 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS11390 f443a536747e41186aa5677752e66fb6 316 Pfam PF02517 CAAX protease self-immunity 223 309 5.4E-20 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CIG75_RS04580 a76e2ed5b2586695557708e92fe78457 226 SUPERFAMILY SSF48613 2 224 4.59E-72 T 28-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CIG75_RS04580 a76e2ed5b2586695557708e92fe78457 226 Gene3D G3DSA:1.20.910.10 1 222 1.6E-57 T 28-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CIG75_RS04580 a76e2ed5b2586695557708e92fe78457 226 TIGRFAM TIGR04306 salvage_TenA: thiaminase II 13 214 9.6E-71 T 28-03-2018 IPR027574 Thiaminase II GO:0006772|GO:0050334 KEGG: 00730+3.5.99.2|MetaCyc: PWY-6899|MetaCyc: PWY-7356 CIG75_RS04580 a76e2ed5b2586695557708e92fe78457 226 Pfam PF03070 TENA/THI-4/PQQC family 9 213 7.4E-55 T 28-03-2018 IPR004305 Thiaminase-2/PQQC CIG75_RS02045 2572521db40dfdcc94bc3049863e5e11 344 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 41 59 2.0E-55 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CIG75_RS02045 2572521db40dfdcc94bc3049863e5e11 344 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 292 318 2.0E-55 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CIG75_RS02045 2572521db40dfdcc94bc3049863e5e11 344 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 124 143 2.0E-55 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CIG75_RS02045 2572521db40dfdcc94bc3049863e5e11 344 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 179 199 2.0E-55 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CIG75_RS02045 2572521db40dfdcc94bc3049863e5e11 344 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 61 84 2.0E-55 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CIG75_RS02045 2572521db40dfdcc94bc3049863e5e11 344 Gene3D G3DSA:3.30.420.40 3 153 3.8E-40 T 28-03-2018 CIG75_RS02045 2572521db40dfdcc94bc3049863e5e11 344 Pfam PF06723 MreB/Mbl protein 5 328 2.2E-145 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CIG75_RS02045 2572521db40dfdcc94bc3049863e5e11 344 SUPERFAMILY SSF53067 2 140 9.89E-40 T 28-03-2018 CIG75_RS02045 2572521db40dfdcc94bc3049863e5e11 344 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 2 328 7.5E-139 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CIG75_RS02045 2572521db40dfdcc94bc3049863e5e11 344 Gene3D G3DSA:3.30.420.40 240 309 2.8E-7 T 28-03-2018 CIG75_RS02045 2572521db40dfdcc94bc3049863e5e11 344 Gene3D G3DSA:3.30.420.40 154 239 6.7E-31 T 28-03-2018 CIG75_RS02045 2572521db40dfdcc94bc3049863e5e11 344 SUPERFAMILY SSF53067 142 324 1.3E-48 T 28-03-2018 CIG75_RS10935 5ba8a5f1072e15e03114a3f9a0d597a0 349 SUPERFAMILY SSF101821 65 171 1.68E-25 T 28-03-2018 CIG75_RS10935 5ba8a5f1072e15e03114a3f9a0d597a0 349 Gene3D G3DSA:3.40.630.10 160 341 4.0E-32 T 28-03-2018 CIG75_RS10935 5ba8a5f1072e15e03114a3f9a0d597a0 349 Pfam PF05343 M42 glutamyl aminopeptidase 38 327 1.5E-85 T 28-03-2018 IPR008007 Peptidase M42 CIG75_RS10935 5ba8a5f1072e15e03114a3f9a0d597a0 349 SUPERFAMILY SSF53187 166 333 2.42E-53 T 28-03-2018 CIG75_RS10935 5ba8a5f1072e15e03114a3f9a0d597a0 349 SUPERFAMILY SSF53187 2 77 2.42E-53 T 28-03-2018 CIG75_RS10935 5ba8a5f1072e15e03114a3f9a0d597a0 349 Gene3D G3DSA:2.40.30.40 64 154 2.2E-28 T 28-03-2018 IPR023367 Peptidase M42, domain 2 CIG75_RS10935 5ba8a5f1072e15e03114a3f9a0d597a0 349 PIRSF PIRSF001123 1 346 7.3E-95 T 28-03-2018 IPR008007 Peptidase M42 CIG75_RS20450 dc6c2bc926ef4d344f2d96a859b790e3 672 PRINTS PR01041 Methionyl-tRNA synthetase signature 355 366 7.1E-34 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CIG75_RS20450 dc6c2bc926ef4d344f2d96a859b790e3 672 PRINTS PR01041 Methionyl-tRNA synthetase signature 89 100 7.1E-34 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CIG75_RS20450 dc6c2bc926ef4d344f2d96a859b790e3 672 PRINTS PR01041 Methionyl-tRNA synthetase signature 41 55 7.1E-34 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CIG75_RS20450 dc6c2bc926ef4d344f2d96a859b790e3 672 PRINTS PR01041 Methionyl-tRNA synthetase signature 9 22 7.1E-34 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CIG75_RS20450 dc6c2bc926ef4d344f2d96a859b790e3 672 PRINTS PR01041 Methionyl-tRNA synthetase signature 227 238 7.1E-34 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CIG75_RS20450 dc6c2bc926ef4d344f2d96a859b790e3 672 PRINTS PR01041 Methionyl-tRNA synthetase signature 263 278 7.1E-34 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CIG75_RS20450 dc6c2bc926ef4d344f2d96a859b790e3 672 Gene3D G3DSA:2.40.50.140 571 671 9.7E-31 T 28-03-2018 CIG75_RS20450 dc6c2bc926ef4d344f2d96a859b790e3 672 SUPERFAMILY SSF47323 357 586 2.99E-43 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CIG75_RS20450 dc6c2bc926ef4d344f2d96a859b790e3 672 Pfam PF01588 Putative tRNA binding domain 578 669 6.6E-29 T 28-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 CIG75_RS20450 dc6c2bc926ef4d344f2d96a859b790e3 672 SUPERFAMILY SSF52374 4 358 5.35E-115 T 28-03-2018 CIG75_RS20450 dc6c2bc926ef4d344f2d96a859b790e3 672 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 543 672 1.3E-43 T 28-03-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CIG75_RS20450 dc6c2bc926ef4d344f2d96a859b790e3 672 Gene3D G3DSA:1.10.730.10 352 518 1.1E-40 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CIG75_RS20450 dc6c2bc926ef4d344f2d96a859b790e3 672 Gene3D G3DSA:3.40.50.620 4 351 7.6E-102 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CIG75_RS20450 dc6c2bc926ef4d344f2d96a859b790e3 672 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 16 25 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CIG75_RS20450 dc6c2bc926ef4d344f2d96a859b790e3 672 Hamap MF_01228 Methionine--tRNA ligase [metG]. 1 515 50.301 T 28-03-2018 IPR023457 Methionine-tRNA synthetase, type 2 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CIG75_RS20450 dc6c2bc926ef4d344f2d96a859b790e3 672 Pfam PF09334 tRNA synthetases class I (M) 7 155 1.0E-50 T 28-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 CIG75_RS20450 dc6c2bc926ef4d344f2d96a859b790e3 672 Pfam PF09334 tRNA synthetases class I (M) 160 367 1.9E-71 T 28-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 CIG75_RS20450 dc6c2bc926ef4d344f2d96a859b790e3 672 Pfam PF08264 Anticodon-binding domain of tRNA 397 484 2.4E-6 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CIG75_RS20450 dc6c2bc926ef4d344f2d96a859b790e3 672 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 7 516 1.6E-173 T 28-03-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CIG75_RS20450 dc6c2bc926ef4d344f2d96a859b790e3 672 SUPERFAMILY SSF50249 571 671 1.98E-34 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CIG75_RS10245 2a73e23e6f6a20008534f6ea088591a7 384 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 4 372 1.4E-101 T 28-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 CIG75_RS10245 2a73e23e6f6a20008534f6ea088591a7 384 Gene3D G3DSA:2.30.40.10 4 66 9.0E-8 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CIG75_RS10245 2a73e23e6f6a20008534f6ea088591a7 384 PIRSF PIRSF038994 3 382 8.2E-131 T 28-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 CIG75_RS10245 2a73e23e6f6a20008534f6ea088591a7 384 SUPERFAMILY SSF51556 52 349 1.49E-100 T 28-03-2018 IPR032466 Metal-dependent hydrolase CIG75_RS10245 2a73e23e6f6a20008534f6ea088591a7 384 Gene3D G3DSA:3.20.20.140 67 349 4.2E-109 T 28-03-2018 CIG75_RS10245 2a73e23e6f6a20008534f6ea088591a7 384 SUPERFAMILY SSF51338 4 51 5.76E-11 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CIG75_RS10245 2a73e23e6f6a20008534f6ea088591a7 384 SUPERFAMILY SSF51338 349 381 5.76E-11 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CIG75_RS10245 2a73e23e6f6a20008534f6ea088591a7 384 Pfam PF01979 Amidohydrolase family 48 363 3.5E-24 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CIG75_RS18625 b9c6f375582e84954770ad47f9b15c61 492 Pfam PF05048 Periplasmic copper-binding protein (NosD) 192 404 1.1E-35 T 28-03-2018 IPR007742 Periplasmic copper-binding protein NosD, beta helix domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 CIG75_RS18625 b9c6f375582e84954770ad47f9b15c61 492 SMART SM00710 214 235 170.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CIG75_RS18625 b9c6f375582e84954770ad47f9b15c61 492 SMART SM00710 258 279 6200.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CIG75_RS18625 b9c6f375582e84954770ad47f9b15c61 492 SMART SM00710 236 257 9.6 T 28-03-2018 IPR006626 Parallel beta-helix repeat CIG75_RS18625 b9c6f375582e84954770ad47f9b15c61 492 SMART SM00710 280 306 4200.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CIG75_RS18625 b9c6f375582e84954770ad47f9b15c61 492 SMART SM00710 329 350 670.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CIG75_RS18625 b9c6f375582e84954770ad47f9b15c61 492 SMART SM00710 185 213 5400.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CIG75_RS18625 b9c6f375582e84954770ad47f9b15c61 492 SMART SM00710 307 328 50.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CIG75_RS18625 b9c6f375582e84954770ad47f9b15c61 492 SUPERFAMILY SSF51126 84 424 1.15E-42 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor CIG75_RS18625 b9c6f375582e84954770ad47f9b15c61 492 TIGRFAM TIGR03804 para_beta_helix: parallel beta-helix repeat 301 342 3.9E-5 T 28-03-2018 IPR022441 Parallel beta-helix repeat-2 Reactome: R-HSA-8951664|Reactome: R-HSA-983168 CIG75_RS18625 b9c6f375582e84954770ad47f9b15c61 492 TIGRFAM TIGR03804 para_beta_helix: parallel beta-helix repeat 208 251 1.7E-6 T 28-03-2018 IPR022441 Parallel beta-helix repeat-2 Reactome: R-HSA-8951664|Reactome: R-HSA-983168 CIG75_RS18625 b9c6f375582e84954770ad47f9b15c61 492 TIGRFAM TIGR03804 para_beta_helix: parallel beta-helix repeat 230 271 1.2E-5 T 28-03-2018 IPR022441 Parallel beta-helix repeat-2 Reactome: R-HSA-8951664|Reactome: R-HSA-983168 CIG75_RS18625 b9c6f375582e84954770ad47f9b15c61 492 TIGRFAM TIGR03804 para_beta_helix: parallel beta-helix repeat 323 364 2.5E-6 T 28-03-2018 IPR022441 Parallel beta-helix repeat-2 Reactome: R-HSA-8951664|Reactome: R-HSA-983168 CIG75_RS18625 b9c6f375582e84954770ad47f9b15c61 492 Gene3D G3DSA:2.160.20.10 83 445 9.7E-44 T 28-03-2018 IPR012334 Pectin lyase fold CIG75_RS06370 dcabdcbc48b45c95b817c1c415a9aa0f 226 Gene3D G3DSA:3.30.240.20 166 226 4.1E-16 T 28-03-2018 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain CIG75_RS06370 dcabdcbc48b45c95b817c1c415a9aa0f 226 Gene3D G3DSA:3.30.240.20 82 151 1.2E-23 T 28-03-2018 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain CIG75_RS06370 dcabdcbc48b45c95b817c1c415a9aa0f 226 Pfam PF04239 Protein of unknown function (DUF421) 88 204 4.8E-37 T 28-03-2018 IPR007353 Protein of unknown function DUF421 CIG75_RS11085 a458b11a6e931a7ec386e47130d37539 292 Pfam PF01882 Protein of unknown function DUF58 41 120 2.6E-17 T 28-03-2018 IPR002881 Domain of unknown function DUF58 CIG75_RS11085 a458b11a6e931a7ec386e47130d37539 292 Gene3D G3DSA:3.40.50.410 52 235 1.0E-22 T 28-03-2018 IPR002035 von Willebrand factor, type A CIG75_RS11085 a458b11a6e931a7ec386e47130d37539 292 SUPERFAMILY SSF53300 82 211 3.64E-9 T 28-03-2018 IPR002035 von Willebrand factor, type A CIG75_RS12435 50b8e672c0b4b113fba4a520931194ba 65 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 7 55 1.8E-4 T 28-03-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 CIG75_RS04660 f7ffa12d7fad0bdb70f52baf2a247d4f 93 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 21 92 20.674 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS04660 f7ffa12d7fad0bdb70f52baf2a247d4f 93 SUPERFAMILY SSF46911 19 91 3.53E-28 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS04660 f7ffa12d7fad0bdb70f52baf2a247d4f 93 TIGRFAM TIGR00165 S18: ribosomal protein bS18 25 91 4.8E-30 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS04660 f7ffa12d7fad0bdb70f52baf2a247d4f 93 PRINTS PR00974 Ribosomal protein S18 family signature 57 64 4.4E-16 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS04660 f7ffa12d7fad0bdb70f52baf2a247d4f 93 PRINTS PR00974 Ribosomal protein S18 family signature 47 57 4.4E-16 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS04660 f7ffa12d7fad0bdb70f52baf2a247d4f 93 PRINTS PR00974 Ribosomal protein S18 family signature 65 79 4.4E-16 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS04660 f7ffa12d7fad0bdb70f52baf2a247d4f 93 PRINTS PR00974 Ribosomal protein S18 family signature 79 89 4.4E-16 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS04660 f7ffa12d7fad0bdb70f52baf2a247d4f 93 Gene3D G3DSA:4.10.640.10 1 93 1.2E-30 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS04660 f7ffa12d7fad0bdb70f52baf2a247d4f 93 ProSitePatterns PS00057 Ribosomal protein S18 signature. 40 63 - T 28-03-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS04660 f7ffa12d7fad0bdb70f52baf2a247d4f 93 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 45 92 3.0E-15 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS04660 f7ffa12d7fad0bdb70f52baf2a247d4f 93 Pfam PF01084 Ribosomal protein S18 37 87 2.1E-23 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS06680 4f799b56b4ea6ea747643b614e20b3a6 1064 TIGRFAM TIGR03891 thiopep_ocin: thiopeptide-type bacteriocin biosynthesis domain 789 1052 6.8E-70 T 28-03-2018 IPR023809 Thiopeptide-type bacteriocin biosynthesis domain CIG75_RS06680 4f799b56b4ea6ea747643b614e20b3a6 1064 Pfam PF04738 Lantibiotic dehydratase, C terminus 63 718 2.8E-191 T 28-03-2018 IPR006827 Lantibiotic dehydratase, C-terminal CIG75_RS06680 4f799b56b4ea6ea747643b614e20b3a6 1064 Pfam PF14028 Lantibiotic biosynthesis dehydratase C-term 789 1053 3.3E-40 T 28-03-2018 IPR023809 Thiopeptide-type bacteriocin biosynthesis domain CIG75_RS03195 003f2267f382a7057b563ff3f12d5969 247 SMART SM00644 10 161 3.2E-21 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CIG75_RS03195 003f2267f382a7057b563ff3f12d5969 247 SUPERFAMILY SSF55846 4 171 7.59E-35 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CIG75_RS03195 003f2267f382a7057b563ff3f12d5969 247 Pfam PF00395 S-layer homology domain 192 233 4.2E-11 T 28-03-2018 IPR001119 S-layer homology domain CIG75_RS03195 003f2267f382a7057b563ff3f12d5969 247 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 21 153 3.2E-20 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CIG75_RS03195 003f2267f382a7057b563ff3f12d5969 247 Gene3D G3DSA:3.40.80.10 2 174 2.6E-33 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CIG75_RS01550 aa7cc7039a5ad53da5d0fce62c481cc5 584 SUPERFAMILY SSF52540 348 504 2.18E-24 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS01550 aa7cc7039a5ad53da5d0fce62c481cc5 584 SMART SM00534 377 577 2.0E-19 T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CIG75_RS01550 aa7cc7039a5ad53da5d0fce62c481cc5 584 Gene3D G3DSA:3.40.50.300 347 581 4.3E-16 T 28-03-2018 CIG75_RS01550 aa7cc7039a5ad53da5d0fce62c481cc5 584 Pfam PF00488 MutS domain V 381 577 3.8E-23 T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CIG75_RS01550 aa7cc7039a5ad53da5d0fce62c481cc5 584 SUPERFAMILY SSF48334 59 297 9.94E-7 T 28-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CIG75_RS01550 aa7cc7039a5ad53da5d0fce62c481cc5 584 Gene3D G3DSA:1.10.1420.10 51 299 8.4E-7 T 28-03-2018 CIG75_RS12510 a330b68660f1a4b7cfa0ef02c3469434 161 PIRSF PIRSF004749 1 155 1.4E-47 T 28-03-2018 IPR023635 Peptide deformylase CIG75_RS12510 a330b68660f1a4b7cfa0ef02c3469434 161 Gene3D G3DSA:3.90.45.10 1 153 5.0E-52 T 28-03-2018 IPR023635 Peptide deformylase CIG75_RS12510 a330b68660f1a4b7cfa0ef02c3469434 161 PRINTS PR01576 Peptide deformylase signature 34 63 1.8E-28 T 28-03-2018 IPR023635 Peptide deformylase CIG75_RS12510 a330b68660f1a4b7cfa0ef02c3469434 161 PRINTS PR01576 Peptide deformylase signature 120 149 1.8E-28 T 28-03-2018 IPR023635 Peptide deformylase CIG75_RS12510 a330b68660f1a4b7cfa0ef02c3469434 161 PRINTS PR01576 Peptide deformylase signature 101 119 1.8E-28 T 28-03-2018 IPR023635 Peptide deformylase CIG75_RS12510 a330b68660f1a4b7cfa0ef02c3469434 161 PRINTS PR01576 Peptide deformylase signature 89 100 1.8E-28 T 28-03-2018 IPR023635 Peptide deformylase CIG75_RS12510 a330b68660f1a4b7cfa0ef02c3469434 161 Hamap MF_00163 Peptide deformylase [def]. 2 160 28.063 T 28-03-2018 IPR023635 Peptide deformylase CIG75_RS12510 a330b68660f1a4b7cfa0ef02c3469434 161 SUPERFAMILY SSF56420 1 148 1.14E-51 T 28-03-2018 IPR023635 Peptide deformylase CIG75_RS12510 a330b68660f1a4b7cfa0ef02c3469434 161 Pfam PF01327 Polypeptide deformylase 4 147 1.2E-45 T 28-03-2018 IPR023635 Peptide deformylase CIG75_RS12510 a330b68660f1a4b7cfa0ef02c3469434 161 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 4 149 1.4E-45 T 28-03-2018 IPR023635 Peptide deformylase CIG75_RS09830 315b43300d10dd1ad14e9f374ddc8030 263 PIRSF PIRSF015626 2 263 1.4E-80 T 28-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 CIG75_RS09830 315b43300d10dd1ad14e9f374ddc8030 263 SUPERFAMILY SSF53927 4 261 1.68E-76 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CIG75_RS09830 315b43300d10dd1ad14e9f374ddc8030 263 Hamap MF_00187 Sulfurtransferase FdhD [fdhD]. 2 262 32.237 T 28-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 CIG75_RS09830 315b43300d10dd1ad14e9f374ddc8030 263 Gene3D G3DSA:3.10.20.10 28 109 2.6E-18 T 28-03-2018 CIG75_RS09830 315b43300d10dd1ad14e9f374ddc8030 263 Gene3D G3DSA:3.40.140.10 127 263 2.4E-48 T 28-03-2018 CIG75_RS09830 315b43300d10dd1ad14e9f374ddc8030 263 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 21 262 3.9E-73 T 28-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 CIG75_RS09830 315b43300d10dd1ad14e9f374ddc8030 263 Pfam PF02634 FdhD/NarQ family 26 261 7.0E-79 T 28-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 CIG75_RS04755 3955811ce9859d4f72dac063e4f905a5 605 Pfam PF09992 Phosphodiester glycosidase 256 397 4.4E-26 T 28-03-2018 IPR018711 Phosphodiester glycosidase CIG75_RS04755 3955811ce9859d4f72dac063e4f905a5 605 Gene3D G3DSA:2.60.40.10 403 492 2.8E-5 T 28-03-2018 IPR013783 Immunoglobulin-like fold CIG75_RS04755 3955811ce9859d4f72dac063e4f905a5 605 Gene3D G3DSA:2.60.40.1080 493 579 1.2E-10 T 28-03-2018 CIG75_RS04755 3955811ce9859d4f72dac063e4f905a5 605 Pfam PF02368 Bacterial Ig-like domain (group 2) 495 574 2.1E-5 T 28-03-2018 IPR003343 Bacterial Ig-like, group 2 CIG75_RS02160 293c13e21772cec3a786da1654b270fc 245 SUPERFAMILY SSF51735 2 243 2.13E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS02160 293c13e21772cec3a786da1654b270fc 245 Pfam PF00106 short chain dehydrogenase 2 189 1.4E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS02160 293c13e21772cec3a786da1654b270fc 245 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 138 166 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CIG75_RS02160 293c13e21772cec3a786da1654b270fc 245 Gene3D G3DSA:3.40.50.720 1 244 1.7E-40 T 28-03-2018 CIG75_RS02160 293c13e21772cec3a786da1654b270fc 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 2.1E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS02160 293c13e21772cec3a786da1654b270fc 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 2.1E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS02160 293c13e21772cec3a786da1654b270fc 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 2.1E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS02160 293c13e21772cec3a786da1654b270fc 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 2.1E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS02160 293c13e21772cec3a786da1654b270fc 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 2.1E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS03570 6949e82901621c7a59c79aed337c9076 379 SUPERFAMILY SSF110738 1 375 2.88E-127 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CIG75_RS03570 6949e82901621c7a59c79aed337c9076 379 Gene3D G3DSA:3.90.1510.10 42 276 9.1E-89 T 28-03-2018 IPR018193 Glycerate kinase, flavodoxin-like domain GO:0008887|GO:0031388 CIG75_RS03570 6949e82901621c7a59c79aed337c9076 379 PIRSF PIRSF006078 1 377 4.3E-131 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CIG75_RS03570 6949e82901621c7a59c79aed337c9076 379 Pfam PF02595 Glycerate kinase family 3 374 7.9E-141 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CIG75_RS03570 6949e82901621c7a59c79aed337c9076 379 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 2 375 5.1E-141 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CIG75_RS03290 16520c3934411e0c75f70c2830e5329b 258 Pfam PF01551 Peptidase family M23 55 148 8.0E-29 T 28-03-2018 IPR016047 Peptidase M23 CIG75_RS03290 16520c3934411e0c75f70c2830e5329b 258 Gene3D G3DSA:2.30.30.410 159 252 1.4E-10 T 28-03-2018 CIG75_RS03290 16520c3934411e0c75f70c2830e5329b 258 SUPERFAMILY SSF51261 52 147 1.15E-36 T 28-03-2018 IPR011055 Duplicated hybrid motif CIG75_RS03290 16520c3934411e0c75f70c2830e5329b 258 Pfam PF08239 Bacterial SH3 domain 187 245 1.1E-7 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type CIG75_RS03290 16520c3934411e0c75f70c2830e5329b 258 Gene3D G3DSA:2.70.70.10 21 158 8.9E-34 T 28-03-2018 CIG75_RS03290 16520c3934411e0c75f70c2830e5329b 258 SMART SM00287 176 249 2.3E-5 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type CIG75_RS08865 ae656e7f85a003697c8e474fa1da696a 585 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 469 580 4.4E-24 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS08865 ae656e7f85a003697c8e474fa1da696a 585 SUPERFAMILY SSF55785 233 346 2.62E-10 T 28-03-2018 IPR000014 PAS domain CIG75_RS08865 ae656e7f85a003697c8e474fa1da696a 585 SUPERFAMILY SSF55874 410 579 4.06E-48 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS08865 ae656e7f85a003697c8e474fa1da696a 585 Gene3D G3DSA:1.10.287.130 351 415 1.1E-19 T 28-03-2018 CIG75_RS08865 ae656e7f85a003697c8e474fa1da696a 585 SMART SM00387 469 581 5.6E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS08865 ae656e7f85a003697c8e474fa1da696a 585 SUPERFAMILY SSF47384 339 422 1.02E-22 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CIG75_RS08865 ae656e7f85a003697c8e474fa1da696a 585 SMART SM00304 183 235 4.9E-6 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CIG75_RS08865 ae656e7f85a003697c8e474fa1da696a 585 Pfam PF00512 His Kinase A (phospho-acceptor) domain 354 421 3.5E-21 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CIG75_RS08865 ae656e7f85a003697c8e474fa1da696a 585 SUPERFAMILY SSF158472 183 234 3.14E-7 T 28-03-2018 CIG75_RS08865 ae656e7f85a003697c8e474fa1da696a 585 SMART SM00091 242 307 0.0019 T 28-03-2018 IPR000014 PAS domain CIG75_RS08865 ae656e7f85a003697c8e474fa1da696a 585 Gene3D G3DSA:3.30.565.10 416 581 5.6E-46 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS08865 ae656e7f85a003697c8e474fa1da696a 585 SMART SM00388 354 421 2.5E-25 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CIG75_RS08865 ae656e7f85a003697c8e474fa1da696a 585 Gene3D G3DSA:3.30.450.20 228 350 1.9E-16 T 28-03-2018 CIG75_RS08865 ae656e7f85a003697c8e474fa1da696a 585 PRINTS PR00344 Bacterial sensor protein C-terminal signature 506 520 9.4E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS08865 ae656e7f85a003697c8e474fa1da696a 585 PRINTS PR00344 Bacterial sensor protein C-terminal signature 541 559 9.4E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS08865 ae656e7f85a003697c8e474fa1da696a 585 PRINTS PR00344 Bacterial sensor protein C-terminal signature 565 578 9.4E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS08865 ae656e7f85a003697c8e474fa1da696a 585 PRINTS PR00344 Bacterial sensor protein C-terminal signature 524 534 9.4E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS08865 ae656e7f85a003697c8e474fa1da696a 585 Pfam PF08448 PAS fold 250 349 3.7E-7 T 28-03-2018 IPR013656 PAS fold-4 CIG75_RS16595 3bc89d9a1a7102ca431daa7e4b5b51e7 427 Pfam PF00512 His Kinase A (phospho-acceptor) domain 209 272 3.6E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CIG75_RS16595 3bc89d9a1a7102ca431daa7e4b5b51e7 427 Gene3D G3DSA:3.30.565.10 274 425 1.5E-39 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS16595 3bc89d9a1a7102ca431daa7e4b5b51e7 427 Pfam PF07694 5TMR of 5TMR-LYT 33 186 2.7E-8 T 28-03-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 CIG75_RS16595 3bc89d9a1a7102ca431daa7e4b5b51e7 427 SUPERFAMILY SSF47384 201 274 1.2E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CIG75_RS16595 3bc89d9a1a7102ca431daa7e4b5b51e7 427 SMART SM00387 315 421 1.5E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS16595 3bc89d9a1a7102ca431daa7e4b5b51e7 427 PRINTS PR00344 Bacterial sensor protein C-terminal signature 352 366 5.6E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS16595 3bc89d9a1a7102ca431daa7e4b5b51e7 427 PRINTS PR00344 Bacterial sensor protein C-terminal signature 405 418 5.6E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS16595 3bc89d9a1a7102ca431daa7e4b5b51e7 427 PRINTS PR00344 Bacterial sensor protein C-terminal signature 381 399 5.6E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS16595 3bc89d9a1a7102ca431daa7e4b5b51e7 427 PRINTS PR00344 Bacterial sensor protein C-terminal signature 370 380 5.6E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS16595 3bc89d9a1a7102ca431daa7e4b5b51e7 427 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 315 419 1.6E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS16595 3bc89d9a1a7102ca431daa7e4b5b51e7 427 SUPERFAMILY SSF55874 266 419 1.44E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS16595 3bc89d9a1a7102ca431daa7e4b5b51e7 427 Gene3D G3DSA:1.10.287.130 196 270 1.1E-12 T 28-03-2018 CIG75_RS16595 3bc89d9a1a7102ca431daa7e4b5b51e7 427 SMART SM00388 208 274 2.4E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CIG75_RS02040 0cefa55c93e197973073cb45d26425f4 102 Pfam PF12116 Stage III sporulation protein D 2 82 8.2E-41 T 28-03-2018 IPR014208 Sporulation stage III, transcriptional regulator SpoIIID CIG75_RS02040 0cefa55c93e197973073cb45d26425f4 102 Gene3D G3DSA:1.10.260.40 33 97 1.4E-6 T 28-03-2018 CIG75_RS02040 0cefa55c93e197973073cb45d26425f4 102 Gene3D G3DSA:1.10.10.10 2 32 6.5E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS02040 0cefa55c93e197973073cb45d26425f4 102 TIGRFAM TIGR02844 spore_III_D: sporulation transcriptional regulator SpoIIID 2 81 4.3E-44 T 28-03-2018 IPR014208 Sporulation stage III, transcriptional regulator SpoIIID CIG75_RS02040 0cefa55c93e197973073cb45d26425f4 102 ProSitePatterns PS00894 DeoR-type HTH domain signature. 8 41 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 CIG75_RS19295 6e1f29ab65576f47a2c05ed85675c897 270 Pfam PF04294 VanW like protein 131 259 2.8E-44 T 28-03-2018 IPR007391 Vancomycin resistance VanW CIG75_RS00715 cc1d59f7937c89c83cd51096070c2b73 193 Gene3D G3DSA:1.10.357.10 54 192 8.0E-11 T 28-03-2018 CIG75_RS00715 cc1d59f7937c89c83cd51096070c2b73 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 6 52 4.9E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CIG75_RS00715 cc1d59f7937c89c83cd51096070c2b73 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 6 19 4.5E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CIG75_RS00715 cc1d59f7937c89c83cd51096070c2b73 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 50 4.5E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CIG75_RS00715 cc1d59f7937c89c83cd51096070c2b73 193 Gene3D G3DSA:1.10.10.60 2 53 1.4E-15 T 28-03-2018 CIG75_RS00715 cc1d59f7937c89c83cd51096070c2b73 193 SUPERFAMILY SSF46689 5 62 3.85E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CIG75_RS00715 cc1d59f7937c89c83cd51096070c2b73 193 SUPERFAMILY SSF48498 78 191 5.44E-6 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CIG75_RS18365 9b9cb01bbc526bd9d57d34e5275cf1b9 121 Gene3D G3DSA:3.30.65.10 1 30 1.8E-8 T 28-03-2018 CIG75_RS18365 9b9cb01bbc526bd9d57d34e5275cf1b9 121 Gene3D G3DSA:3.30.65.10 31 87 9.7E-12 T 28-03-2018 CIG75_RS18365 9b9cb01bbc526bd9d57d34e5275cf1b9 121 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 1 26 1.4E-8 T 28-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 CIG75_RS18365 9b9cb01bbc526bd9d57d34e5275cf1b9 121 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 46 78 1.7E-8 T 28-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 CIG75_RS18365 9b9cb01bbc526bd9d57d34e5275cf1b9 121 SUPERFAMILY SSF57783 40 80 9.69E-9 T 28-03-2018 CIG75_RS18365 9b9cb01bbc526bd9d57d34e5275cf1b9 121 SUPERFAMILY SSF57783 1 28 1.29E-7 T 28-03-2018 CIG75_RS19600 1142b72bb11cdafcd3f218b432f3f7d9 136 ProSitePatterns PS00054 Ribosomal protein S11 signature. 104 126 - T 28-03-2018 IPR018102 Ribosomal S11, conserved site CIG75_RS19600 1142b72bb11cdafcd3f218b432f3f7d9 136 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 3 136 34.166 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CIG75_RS19600 1142b72bb11cdafcd3f218b432f3f7d9 136 PIRSF PIRSF002131 3 136 1.8E-52 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CIG75_RS19600 1142b72bb11cdafcd3f218b432f3f7d9 136 Pfam PF00411 Ribosomal protein S11 26 135 3.3E-51 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CIG75_RS19600 1142b72bb11cdafcd3f218b432f3f7d9 136 SUPERFAMILY SSF53137 21 136 5.3E-50 T 28-03-2018 CIG75_RS19600 1142b72bb11cdafcd3f218b432f3f7d9 136 Gene3D G3DSA:3.30.420.80 12 136 3.2E-46 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CIG75_RS19600 1142b72bb11cdafcd3f218b432f3f7d9 136 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 18 133 1.2E-57 T 28-03-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS19925 5f3050c4eaf1a7ff2dbd870bd24a9b0f 578 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 29 345 6.9E-20 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CIG75_RS19925 5f3050c4eaf1a7ff2dbd870bd24a9b0f 578 Gene3D G3DSA:3.40.50.300 5 385 2.7E-27 T 28-03-2018 CIG75_RS19925 5f3050c4eaf1a7ff2dbd870bd24a9b0f 578 SUPERFAMILY SSF52540 5 354 9.21E-24 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS15795 e9955797f78e33522c8ea4e8c717b743 729 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 171 508 6.2E-101 T 28-03-2018 CIG75_RS15795 e9955797f78e33522c8ea4e8c717b743 729 SUPERFAMILY SSF81653 223 320 8.89E-27 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CIG75_RS15795 e9955797f78e33522c8ea4e8c717b743 729 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 193 709 2.8E-88 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CIG75_RS15795 e9955797f78e33522c8ea4e8c717b743 729 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 569 579 1.2E-26 T 28-03-2018 CIG75_RS15795 e9955797f78e33522c8ea4e8c717b743 729 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 270 284 1.2E-26 T 28-03-2018 CIG75_RS15795 e9955797f78e33522c8ea4e8c717b743 729 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 646 658 1.2E-26 T 28-03-2018 CIG75_RS15795 e9955797f78e33522c8ea4e8c717b743 729 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 622 641 1.2E-26 T 28-03-2018 CIG75_RS15795 e9955797f78e33522c8ea4e8c717b743 729 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 421 435 1.2E-26 T 28-03-2018 CIG75_RS15795 e9955797f78e33522c8ea4e8c717b743 729 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 546 557 1.2E-26 T 28-03-2018 CIG75_RS15795 e9955797f78e33522c8ea4e8c717b743 729 SUPERFAMILY SSF55008 21 86 1.27E-16 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CIG75_RS15795 e9955797f78e33522c8ea4e8c717b743 729 PRINTS PR00941 Cadmium-transporting ATPase signature 24 33 4.6E-31 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CIG75_RS15795 e9955797f78e33522c8ea4e8c717b743 729 PRINTS PR00941 Cadmium-transporting ATPase signature 151 163 4.6E-31 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CIG75_RS15795 e9955797f78e33522c8ea4e8c717b743 729 PRINTS PR00941 Cadmium-transporting ATPase signature 57 80 4.6E-31 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CIG75_RS15795 e9955797f78e33522c8ea4e8c717b743 729 PRINTS PR00941 Cadmium-transporting ATPase signature 205 225 4.6E-31 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CIG75_RS15795 e9955797f78e33522c8ea4e8c717b743 729 PRINTS PR00941 Cadmium-transporting ATPase signature 225 241 4.6E-31 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CIG75_RS15795 e9955797f78e33522c8ea4e8c717b743 729 PRINTS PR00941 Cadmium-transporting ATPase signature 305 319 4.6E-31 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CIG75_RS15795 e9955797f78e33522c8ea4e8c717b743 729 PRINTS PR00941 Cadmium-transporting ATPase signature 286 302 4.6E-31 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CIG75_RS15795 e9955797f78e33522c8ea4e8c717b743 729 PRINTS PR00941 Cadmium-transporting ATPase signature 35 56 4.6E-31 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CIG75_RS15795 e9955797f78e33522c8ea4e8c717b743 729 Pfam PF00702 haloacid dehalogenase-like hydrolase 417 636 7.1E-45 T 28-03-2018 CIG75_RS15795 e9955797f78e33522c8ea4e8c717b743 729 SUPERFAMILY SSF81665 169 224 4.97E-21 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CIG75_RS15795 e9955797f78e33522c8ea4e8c717b743 729 SUPERFAMILY SSF81665 672 711 4.97E-21 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CIG75_RS15795 e9955797f78e33522c8ea4e8c717b743 729 SUPERFAMILY SSF81665 321 415 4.97E-21 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CIG75_RS15795 e9955797f78e33522c8ea4e8c717b743 729 SUPERFAMILY SSF56784 420 439 2.12E-57 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS15795 e9955797f78e33522c8ea4e8c717b743 729 SUPERFAMILY SSF56784 478 722 2.12E-57 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS15795 e9955797f78e33522c8ea4e8c717b743 729 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 170 725 2.4E-198 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CIG75_RS15795 e9955797f78e33522c8ea4e8c717b743 729 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 187 725 1.9E-127 T 28-03-2018 CIG75_RS15795 e9955797f78e33522c8ea4e8c717b743 729 Pfam PF00122 E1-E2 ATPase 222 401 1.4E-57 T 28-03-2018 CIG75_RS15795 e9955797f78e33522c8ea4e8c717b743 729 Pfam PF00403 Heavy-metal-associated domain 23 80 4.2E-15 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CIG75_RS15795 e9955797f78e33522c8ea4e8c717b743 729 Gene3D G3DSA:3.30.70.100 5 93 3.5E-19 T 28-03-2018 CIG75_RS15795 e9955797f78e33522c8ea4e8c717b743 729 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 423 429 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CIG75_RS15795 e9955797f78e33522c8ea4e8c717b743 729 Gene3D G3DSA:3.40.1110.10 444 547 3.9E-32 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CIG75_RS15795 e9955797f78e33522c8ea4e8c717b743 729 Gene3D G3DSA:3.40.50.1000 548 689 2.7E-39 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS15795 e9955797f78e33522c8ea4e8c717b743 729 Gene3D G3DSA:1.20.1110.10 140 443 5.5E-44 T 28-03-2018 CIG75_RS13840 a563e790bac980ff9f4dcf08d1602316 148 PRINTS PR01467 Bacterial arginine repressor signature 36 51 3.7E-27 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CIG75_RS13840 a563e790bac980ff9f4dcf08d1602316 148 PRINTS PR01467 Bacterial arginine repressor signature 87 100 3.7E-27 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CIG75_RS13840 a563e790bac980ff9f4dcf08d1602316 148 PRINTS PR01467 Bacterial arginine repressor signature 20 33 3.7E-27 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CIG75_RS13840 a563e790bac980ff9f4dcf08d1602316 148 PRINTS PR01467 Bacterial arginine repressor signature 117 132 3.7E-27 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CIG75_RS13840 a563e790bac980ff9f4dcf08d1602316 148 Pfam PF01316 Arginine repressor, DNA binding domain 2 67 1.3E-26 T 28-03-2018 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 CIG75_RS13840 a563e790bac980ff9f4dcf08d1602316 148 TIGRFAM TIGR01529 argR_whole: arginine repressor 4 145 4.2E-51 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CIG75_RS13840 a563e790bac980ff9f4dcf08d1602316 148 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 86 148 2.0E-20 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CIG75_RS13840 a563e790bac980ff9f4dcf08d1602316 148 SUPERFAMILY SSF55252 79 147 1.44E-21 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CIG75_RS13840 a563e790bac980ff9f4dcf08d1602316 148 SUPERFAMILY SSF46785 2 77 7.39E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS13840 a563e790bac980ff9f4dcf08d1602316 148 Pfam PF02863 Arginine repressor, C-terminal domain 81 144 1.9E-27 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CIG75_RS13840 a563e790bac980ff9f4dcf08d1602316 148 Hamap MF_00173 Arginine repressor [argR]. 1 148 68.121 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CIG75_RS13840 a563e790bac980ff9f4dcf08d1602316 148 Gene3D G3DSA:1.10.10.10 2 65 6.9E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS13840 a563e790bac980ff9f4dcf08d1602316 148 Gene3D G3DSA:3.30.1360.40 73 145 4.5E-29 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CIG75_RS03920 5494da35023380efe6b3a71d7de7e758 343 TIGRFAM TIGR04432 rSAM_Cfr: 23S rRNA (adenine(2503)-C(8))-methyltransferase Cfr 4 341 1.6E-187 T 28-03-2018 IPR022881 Ribosomal RNA large subunit methyltransferase, Cfr GO:0070475 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6828 CIG75_RS03920 5494da35023380efe6b3a71d7de7e758 343 SUPERFAMILY SSF102114 101 294 7.46E-12 T 28-03-2018 CIG75_RS03920 5494da35023380efe6b3a71d7de7e758 343 Gene3D G3DSA:3.20.20.70 8 339 7.3E-29 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CIG75_RS03920 5494da35023380efe6b3a71d7de7e758 343 PIRSF PIRSF006004 5 343 1.4E-94 T 28-03-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CIG75_RS03920 5494da35023380efe6b3a71d7de7e758 343 Hamap MF_01873 Ribosomal RNA large subunit methyltransferase Cfr [cfr]. 1 343 63.718 T 28-03-2018 IPR022881 Ribosomal RNA large subunit methyltransferase, Cfr GO:0070475 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6828 CIG75_RS03920 5494da35023380efe6b3a71d7de7e758 343 Pfam PF04055 Radical SAM superfamily 105 267 3.3E-12 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CIG75_RS14085 f56d8f727b1cb41a634e418f0ce870ad 213 SMART SM00464 5 198 1.1E-17 T 28-03-2018 IPR003111 Lon, substrate-binding domain CIG75_RS14085 f56d8f727b1cb41a634e418f0ce870ad 213 Gene3D G3DSA:1.10.4060.10 118 205 1.2E-9 T 28-03-2018 CIG75_RS14085 f56d8f727b1cb41a634e418f0ce870ad 213 SUPERFAMILY SSF88697 5 197 7.46E-45 T 28-03-2018 IPR015947 PUA-like domain CIG75_RS14085 f56d8f727b1cb41a634e418f0ce870ad 213 Gene3D G3DSA:2.30.130.40 3 112 2.7E-26 T 28-03-2018 CIG75_RS14085 f56d8f727b1cb41a634e418f0ce870ad 213 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 6 197 5.4E-26 T 28-03-2018 IPR003111 Lon, substrate-binding domain CIG75_RS12495 9eb3eb8ec26c1e074675715f42712753 359 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 12 356 2.9E-136 T 28-03-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CIG75_RS12495 9eb3eb8ec26c1e074675715f42712753 359 Pfam PF13394 4Fe-4S single cluster domain 122 227 1.7E-6 T 28-03-2018 CIG75_RS12495 9eb3eb8ec26c1e074675715f42712753 359 Pfam PF04055 Radical SAM superfamily 118 286 1.6E-16 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CIG75_RS12495 9eb3eb8ec26c1e074675715f42712753 359 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 14 358 72.697 T 28-03-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CIG75_RS12495 9eb3eb8ec26c1e074675715f42712753 359 PIRSF PIRSF006004 7 358 1.5E-134 T 28-03-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CIG75_RS12495 9eb3eb8ec26c1e074675715f42712753 359 SUPERFAMILY SSF102114 104 312 7.06E-13 T 28-03-2018 CIG75_RS12495 9eb3eb8ec26c1e074675715f42712753 359 Gene3D G3DSA:3.20.20.70 24 357 4.1E-38 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CIG75_RS07870 e2790bf71a119ea23249962f1b059a31 273 SUPERFAMILY SSF161098 74 256 5.36E-32 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CIG75_RS07870 e2790bf71a119ea23249962f1b059a31 273 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 262 7.9E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CIG75_RS07870 e2790bf71a119ea23249962f1b059a31 273 Gene3D G3DSA:1.10.3720.10 23 273 1.1E-27 T 28-03-2018 CIG75_RS12210 054fcab29972461b7ff23a40b6909fed 275 SUPERFAMILY SSF53098 67 267 2.88E-65 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CIG75_RS12210 054fcab29972461b7ff23a40b6909fed 275 Pfam PF01351 Ribonuclease HII 80 260 3.1E-34 T 28-03-2018 IPR024567 Ribonuclease HII/HIII domain CIG75_RS12210 054fcab29972461b7ff23a40b6909fed 275 Gene3D G3DSA:3.30.420.10 55 270 1.6E-69 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CIG75_RS12210 054fcab29972461b7ff23a40b6909fed 275 Hamap MF_00052_B Ribonuclease HII [rnhB]. 78 261 33.912 T 28-03-2018 IPR022898 Ribonuclease HII GO:0004523 CIG75_RS08505 37d87912681879511aa4143d87b81793 300 Pfam PF00892 EamA-like transporter family 5 137 2.9E-22 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CIG75_RS08505 37d87912681879511aa4143d87b81793 300 Pfam PF00892 EamA-like transporter family 150 286 5.8E-25 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CIG75_RS08505 37d87912681879511aa4143d87b81793 300 SUPERFAMILY SSF103481 40 140 1.14E-13 T 28-03-2018 CIG75_RS08505 37d87912681879511aa4143d87b81793 300 SUPERFAMILY SSF103481 185 293 9.81E-15 T 28-03-2018 CIG75_RS10280 4f2034fb56769c2d59cf9531a477b1bd 397 SUPERFAMILY SSF53756 1 369 1.18E-72 T 28-03-2018 CIG75_RS10280 4f2034fb56769c2d59cf9531a477b1bd 397 Gene3D G3DSA:3.40.50.2000 10 178 1.1E-10 T 28-03-2018 CIG75_RS10280 4f2034fb56769c2d59cf9531a477b1bd 397 Pfam PF00534 Glycosyl transferases group 1 192 338 2.3E-33 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CIG75_RS10280 4f2034fb56769c2d59cf9531a477b1bd 397 Pfam PF13439 Glycosyltransferase Family 4 15 180 2.0E-21 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CIG75_RS10280 4f2034fb56769c2d59cf9531a477b1bd 397 Gene3D G3DSA:3.40.50.2000 179 361 1.3E-40 T 28-03-2018 CIG75_RS08140 cd233fc01921cc6439d2596eaa16503a 129 Pfam PF14464 Prokaryotic homologs of the JAB domain 9 116 9.6E-16 T 28-03-2018 IPR028090 JAB domain, prokaryotic CIG75_RS08140 cd233fc01921cc6439d2596eaa16503a 129 Gene3D G3DSA:3.40.140.10 1 127 3.6E-12 T 28-03-2018 CIG75_RS08140 cd233fc01921cc6439d2596eaa16503a 129 SUPERFAMILY SSF102712 2 121 3.66E-20 T 28-03-2018 CIG75_RS15100 d5c68f89b2e15b0b0c3a078130b7cf3e 237 SUPERFAMILY SSF54106 52 97 2.09E-10 T 28-03-2018 IPR018392 LysM domain CIG75_RS15100 d5c68f89b2e15b0b0c3a078130b7cf3e 237 Pfam PF06725 3D domain 169 230 2.9E-14 T 28-03-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 CIG75_RS15100 d5c68f89b2e15b0b0c3a078130b7cf3e 237 Pfam PF01476 LysM domain 54 97 6.4E-12 T 28-03-2018 IPR018392 LysM domain CIG75_RS15100 d5c68f89b2e15b0b0c3a078130b7cf3e 237 SMART SM00257 53 97 2.0E-12 T 28-03-2018 IPR018392 LysM domain CIG75_RS15100 d5c68f89b2e15b0b0c3a078130b7cf3e 237 SUPERFAMILY SSF50685 156 218 9.07E-8 T 28-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CIG75_RS15100 d5c68f89b2e15b0b0c3a078130b7cf3e 237 Gene3D G3DSA:2.40.40.10 40 236 4.7E-32 T 28-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CIG75_RS06735 2de742b5b4a9c56693aacdf77d989fdf 2386 SUPERFAMILY SSF52777 49 226 8.67E-49 T 28-03-2018 CIG75_RS06735 2de742b5b4a9c56693aacdf77d989fdf 2386 Gene3D G3DSA:3.30.559.10 1091 1283 7.1E-43 T 28-03-2018 CIG75_RS06735 2de742b5b4a9c56693aacdf77d989fdf 2386 Gene3D G3DSA:3.40.50.980 504 659 1.6E-48 T 28-03-2018 CIG75_RS06735 2de742b5b4a9c56693aacdf77d989fdf 2386 Gene3D G3DSA:3.40.50.980 1554 1705 2.1E-46 T 28-03-2018 CIG75_RS06735 2de742b5b4a9c56693aacdf77d989fdf 2386 Pfam PF00975 Thioesterase domain 2146 2382 1.1E-35 T 28-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CIG75_RS06735 2de742b5b4a9c56693aacdf77d989fdf 2386 Gene3D G3DSA:3.30.559.10 33 248 1.3E-44 T 28-03-2018 CIG75_RS06735 2de742b5b4a9c56693aacdf77d989fdf 2386 SUPERFAMILY SSF52777 1106 1277 8.23E-49 T 28-03-2018 CIG75_RS06735 2de742b5b4a9c56693aacdf77d989fdf 2386 Gene3D G3DSA:3.40.50.980 1706 1859 1.1E-26 T 28-03-2018 CIG75_RS06735 2de742b5b4a9c56693aacdf77d989fdf 2386 Gene3D G3DSA:3.40.50.980 660 821 6.7E-25 T 28-03-2018 CIG75_RS06735 2de742b5b4a9c56693aacdf77d989fdf 2386 SMART SM00823 Phosphopantetheine attachment site 1019 1088 2.9E-5 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS06735 2de742b5b4a9c56693aacdf77d989fdf 2386 SMART SM00823 Phosphopantetheine attachment site 2059 2128 7.9E-8 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS06735 2de742b5b4a9c56693aacdf77d989fdf 2386 SUPERFAMILY SSF56801 1521 2072 6.93E-152 T 28-03-2018 CIG75_RS06735 2de742b5b4a9c56693aacdf77d989fdf 2386 ProSitePatterns PS00455 Putative AMP-binding domain signature. 654 665 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS06735 2de742b5b4a9c56693aacdf77d989fdf 2386 SUPERFAMILY SSF52777 1284 1547 4.11E-68 T 28-03-2018 CIG75_RS06735 2de742b5b4a9c56693aacdf77d989fdf 2386 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2083 2098 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS06735 2de742b5b4a9c56693aacdf77d989fdf 2386 Pfam PF00668 Condensation domain 49 491 3.4E-110 T 28-03-2018 IPR001242 Condensation domain CIG75_RS06735 2de742b5b4a9c56693aacdf77d989fdf 2386 Pfam PF00668 Condensation domain 1102 1542 4.0E-117 T 28-03-2018 IPR001242 Condensation domain CIG75_RS06735 2de742b5b4a9c56693aacdf77d989fdf 2386 SUPERFAMILY SSF52777 234 499 6.11E-60 T 28-03-2018 CIG75_RS06735 2de742b5b4a9c56693aacdf77d989fdf 2386 SUPERFAMILY SSF56801 470 1032 1.96E-154 T 28-03-2018 CIG75_RS06735 2de742b5b4a9c56693aacdf77d989fdf 2386 Pfam PF00550 Phosphopantetheine attachment site 2061 2123 3.5E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS06735 2de742b5b4a9c56693aacdf77d989fdf 2386 Pfam PF00550 Phosphopantetheine attachment site 1021 1084 3.2E-16 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS06735 2de742b5b4a9c56693aacdf77d989fdf 2386 SMART SM00824 Thioesterase 2157 2386 7.2E-4 T 28-03-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 CIG75_RS06735 2de742b5b4a9c56693aacdf77d989fdf 2386 Gene3D G3DSA:1.10.1200.10 2065 2129 1.1E-21 T 28-03-2018 CIG75_RS06735 2de742b5b4a9c56693aacdf77d989fdf 2386 Gene3D G3DSA:1.10.1200.10 1025 1090 1.1E-24 T 28-03-2018 CIG75_RS06735 2de742b5b4a9c56693aacdf77d989fdf 2386 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1700 1711 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS06735 2de742b5b4a9c56693aacdf77d989fdf 2386 Pfam PF13193 AMP-binding enzyme C-terminal domain 923 992 1.1E-12 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS06735 2de742b5b4a9c56693aacdf77d989fdf 2386 Pfam PF13193 AMP-binding enzyme C-terminal domain 1958 2032 1.1E-12 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS06735 2de742b5b4a9c56693aacdf77d989fdf 2386 SUPERFAMILY SSF47336 2052 2124 4.84E-20 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS06735 2de742b5b4a9c56693aacdf77d989fdf 2386 Pfam PF00501 AMP-binding enzyme 513 915 7.2E-93 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS06735 2de742b5b4a9c56693aacdf77d989fdf 2386 Pfam PF00501 AMP-binding enzyme 1563 1950 1.3E-92 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS06735 2de742b5b4a9c56693aacdf77d989fdf 2386 SUPERFAMILY SSF47336 1011 1085 4.19E-21 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS06735 2de742b5b4a9c56693aacdf77d989fdf 2386 Gene3D G3DSA:2.30.38.10 823 905 5.0E-24 T 28-03-2018 CIG75_RS06735 2de742b5b4a9c56693aacdf77d989fdf 2386 SUPERFAMILY SSF53474 2126 2385 8.36E-58 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS06735 2de742b5b4a9c56693aacdf77d989fdf 2386 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1584 1974 4.8E-127 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS06735 2de742b5b4a9c56693aacdf77d989fdf 2386 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 534 939 1.2E-130 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS06735 2de742b5b4a9c56693aacdf77d989fdf 2386 Gene3D G3DSA:3.30.300.30 1945 2064 1.6E-38 T 28-03-2018 CIG75_RS06735 2de742b5b4a9c56693aacdf77d989fdf 2386 Gene3D G3DSA:3.30.300.30 910 1024 5.6E-38 T 28-03-2018 CIG75_RS06735 2de742b5b4a9c56693aacdf77d989fdf 2386 Gene3D G3DSA:3.40.50.1820 2130 2386 2.0E-28 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS06735 2de742b5b4a9c56693aacdf77d989fdf 2386 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1043 1058 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS06735 2de742b5b4a9c56693aacdf77d989fdf 2386 Gene3D G3DSA:2.30.38.10 1860 1943 7.2E-23 T 28-03-2018 CIG75_RS11350 a65fed2dee4afb804576d900b85345f8 411 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 177 236 1.2E-13 T 28-03-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 CIG75_RS11350 a65fed2dee4afb804576d900b85345f8 411 Gene3D G3DSA:1.10.3090.10 149 407 8.9E-43 T 28-03-2018 CIG75_RS11350 a65fed2dee4afb804576d900b85345f8 411 SUPERFAMILY SSF81891 147 406 1.57E-45 T 28-03-2018 CIG75_RS11350 a65fed2dee4afb804576d900b85345f8 411 SUPERFAMILY SSF81301 14 145 2.51E-41 T 28-03-2018 CIG75_RS11350 a65fed2dee4afb804576d900b85345f8 411 Pfam PF01743 Poly A polymerase head domain 29 149 3.9E-32 T 28-03-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 CIG75_RS11350 a65fed2dee4afb804576d900b85345f8 411 Gene3D G3DSA:3.30.460.10 8 148 4.7E-45 T 28-03-2018 CIG75_RS11350 a65fed2dee4afb804576d900b85345f8 411 Pfam PF13735 tRNA nucleotidyltransferase domain 2 putative 258 403 3.9E-12 T 28-03-2018 IPR032810 CCA-adding enzyme, C-terminal CIG75_RS00950 5a426c30146c69aa68b879adc9337fc8 527 SUPERFAMILY SSF53474 11 242 1.79E-46 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS00950 5a426c30146c69aa68b879adc9337fc8 527 Gene3D G3DSA:3.40.50.1820 266 527 4.1E-25 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS00950 5a426c30146c69aa68b879adc9337fc8 527 Gene3D G3DSA:3.40.50.1820 5 253 3.3E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS00950 5a426c30146c69aa68b879adc9337fc8 527 Pfam PF00756 Putative esterase 12 240 1.1E-26 T 28-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 CIG75_RS00950 5a426c30146c69aa68b879adc9337fc8 527 Pfam PF00756 Putative esterase 278 478 3.0E-22 T 28-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 CIG75_RS00950 5a426c30146c69aa68b879adc9337fc8 527 SUPERFAMILY SSF53474 261 522 1.73E-60 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS00365 ace789895d91b7fecddd4c3bc5b6b742 94 Pfam PF01250 Ribosomal protein S6 3 92 2.6E-29 T 28-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS00365 ace789895d91b7fecddd4c3bc5b6b742 94 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 92 2.1E-26 T 28-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS00365 ace789895d91b7fecddd4c3bc5b6b742 94 SUPERFAMILY SSF54995 1 93 4.71E-31 T 28-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS00365 ace789895d91b7fecddd4c3bc5b6b742 94 Gene3D G3DSA:3.30.70.60 1 94 4.1E-30 T 28-03-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 CIG75_RS00365 ace789895d91b7fecddd4c3bc5b6b742 94 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 94 18.512 T 28-03-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 CIG75_RS00870 ad538aaab906341e471cbc5755cd6ea2 305 Gene3D G3DSA:3.40.50.2020 1 146 7.9E-33 T 28-03-2018 CIG75_RS00870 ad538aaab906341e471cbc5755cd6ea2 305 Gene3D G3DSA:3.40.50.2020 147 278 2.2E-15 T 28-03-2018 CIG75_RS00870 ad538aaab906341e471cbc5755cd6ea2 305 SMART SM01400 4 120 1.1E-23 T 28-03-2018 CIG75_RS00870 ad538aaab906341e471cbc5755cd6ea2 305 SUPERFAMILY SSF53271 85 289 8.09E-23 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CIG75_RS00870 ad538aaab906341e471cbc5755cd6ea2 305 Pfam PF00156 Phosphoribosyl transferase domain 151 256 4.4E-8 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CIG75_RS00870 ad538aaab906341e471cbc5755cd6ea2 305 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 7 120 1.5E-21 T 28-03-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CIG75_RS00870 ad538aaab906341e471cbc5755cd6ea2 305 SUPERFAMILY SSF53271 2 157 2.2E-31 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CIG75_RS00870 ad538aaab906341e471cbc5755cd6ea2 305 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 6 292 3.7E-57 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CIG75_RS08055 f67e3c5988c7c2a139417c926d7e26cf 472 Pfam PF00206 Lyase 12 341 3.2E-104 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal CIG75_RS08055 f67e3c5988c7c2a139417c926d7e26cf 472 ProSitePatterns PS00163 Fumarate lyases signature. 316 325 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 CIG75_RS08055 f67e3c5988c7c2a139417c926d7e26cf 472 SUPERFAMILY SSF48557 4 459 5.15E-149 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 CIG75_RS08055 f67e3c5988c7c2a139417c926d7e26cf 472 PRINTS PR00145 Argininosuccinate lyase family signature 174 194 1.4E-5 T 28-03-2018 CIG75_RS08055 f67e3c5988c7c2a139417c926d7e26cf 472 PRINTS PR00145 Argininosuccinate lyase family signature 316 332 1.4E-5 T 28-03-2018 CIG75_RS08055 f67e3c5988c7c2a139417c926d7e26cf 472 PRINTS PR00149 Fumarate lyase superfamily signature 134 152 4.0E-33 T 28-03-2018 IPR000362 Fumarate lyase family CIG75_RS08055 f67e3c5988c7c2a139417c926d7e26cf 472 PRINTS PR00149 Fumarate lyase superfamily signature 316 332 4.0E-33 T 28-03-2018 IPR000362 Fumarate lyase family CIG75_RS08055 f67e3c5988c7c2a139417c926d7e26cf 472 PRINTS PR00149 Fumarate lyase superfamily signature 270 297 4.0E-33 T 28-03-2018 IPR000362 Fumarate lyase family CIG75_RS08055 f67e3c5988c7c2a139417c926d7e26cf 472 PRINTS PR00149 Fumarate lyase superfamily signature 179 197 4.0E-33 T 28-03-2018 IPR000362 Fumarate lyase family CIG75_RS08055 f67e3c5988c7c2a139417c926d7e26cf 472 TIGRFAM TIGR00839 aspA: aspartate ammonia-lyase 5 467 2.7E-217 T 28-03-2018 IPR004708 Aspartate ammonia-lyase GO:0006531|GO:0008797 KEGG: 00250+4.3.1.1 CIG75_RS08055 f67e3c5988c7c2a139417c926d7e26cf 472 Gene3D G3DSA:1.10.275.10 2 137 3.8E-53 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal CIG75_RS08055 f67e3c5988c7c2a139417c926d7e26cf 472 Gene3D G3DSA:1.10.40.30 414 461 4.4E-22 T 28-03-2018 CIG75_RS08055 f67e3c5988c7c2a139417c926d7e26cf 472 Gene3D G3DSA:1.20.200.10 138 413 1.6E-80 T 28-03-2018 CIG75_RS08055 f67e3c5988c7c2a139417c926d7e26cf 472 Pfam PF10415 Fumarase C C-terminus 407 459 6.2E-22 T 28-03-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CIG75_RS09540 eb81c0709c62174bf59b0c1ed47cfd4a 296 SUPERFAMILY SSF48452 17 207 6.26E-20 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS09540 eb81c0709c62174bf59b0c1ed47cfd4a 296 Gene3D G3DSA:3.30.70.100 57 99 4.6E-5 T 28-03-2018 CIG75_RS09540 eb81c0709c62174bf59b0c1ed47cfd4a 296 Gene3D G3DSA:3.30.70.100 100 148 3.2E-6 T 28-03-2018 CIG75_RS09540 eb81c0709c62174bf59b0c1ed47cfd4a 296 Gene3D G3DSA:1.25.40.10 2 56 0.0025 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS09540 eb81c0709c62174bf59b0c1ed47cfd4a 296 Gene3D G3DSA:1.25.40.10 152 294 1.6E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS09540 eb81c0709c62174bf59b0c1ed47cfd4a 296 SMART SM00028 178 211 69.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS09540 eb81c0709c62174bf59b0c1ed47cfd4a 296 SMART SM00028 17 50 42.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS09540 eb81c0709c62174bf59b0c1ed47cfd4a 296 SMART SM00028 58 91 360.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS09540 eb81c0709c62174bf59b0c1ed47cfd4a 296 SMART SM00028 98 131 0.028 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS10115 5623e20614a906ae1e8ec21c35c37010 337 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 248 336 2.0E-17 T 28-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CIG75_RS10115 5623e20614a906ae1e8ec21c35c37010 337 Gene3D G3DSA:3.40.47.10 4 209 2.0E-23 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS10115 5623e20614a906ae1e8ec21c35c37010 337 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 110 191 6.3E-16 T 28-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CIG75_RS10115 5623e20614a906ae1e8ec21c35c37010 337 SUPERFAMILY SSF53901 4 336 3.39E-33 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS10115 5623e20614a906ae1e8ec21c35c37010 337 Gene3D G3DSA:3.40.47.10 210 336 4.0E-18 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS13180 fb75bc70530179c116e65993909a1a34 260 Pfam PF01479 S4 domain 190 230 4.2E-6 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CIG75_RS13180 fb75bc70530179c116e65993909a1a34 260 Gene3D G3DSA:3.10.290.10 182 238 8.9E-10 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CIG75_RS13180 fb75bc70530179c116e65993909a1a34 260 SUPERFAMILY SSF55174 181 252 9.81E-25 T 28-03-2018 CIG75_RS13180 fb75bc70530179c116e65993909a1a34 260 SUPERFAMILY SSF55174 38 129 9.81E-25 T 28-03-2018 CIG75_RS13180 fb75bc70530179c116e65993909a1a34 260 SMART SM00363 184 249 4.3E-8 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CIG75_RS14125 0b29aee49196e36c5b81f048c319b579 244 SUPERFAMILY SSF52317 35 215 8.06E-26 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CIG75_RS14125 0b29aee49196e36c5b81f048c319b579 244 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 4 200 1.2E-45 T 28-03-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 CIG75_RS14125 0b29aee49196e36c5b81f048c319b579 244 Gene3D G3DSA:3.40.50.880 12 220 1.4E-18 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CIG75_RS07795 4511d3aba78592d433cc6443149d91d0 267 SUPERFAMILY SSF53681 6 108 9.48E-34 T 28-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CIG75_RS07795 4511d3aba78592d433cc6443149d91d0 267 SUPERFAMILY SSF53681 111 262 2.35E-39 T 28-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CIG75_RS07795 4511d3aba78592d433cc6443149d91d0 267 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 181 191 - T 28-03-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CIG75_RS07795 4511d3aba78592d433cc6443149d91d0 267 Hamap MF_00258 Glutamate racemase [murI]. 5 257 38.156 T 28-03-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CIG75_RS07795 4511d3aba78592d433cc6443149d91d0 267 Pfam PF01177 Asp/Glu/Hydantoin racemase 7 216 5.3E-36 T 28-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CIG75_RS07795 4511d3aba78592d433cc6443149d91d0 267 TIGRFAM TIGR00067 glut_race: glutamate racemase 7 255 7.5E-80 T 28-03-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CIG75_RS07795 4511d3aba78592d433cc6443149d91d0 267 Gene3D G3DSA:3.40.50.1860 116 265 1.6E-45 T 28-03-2018 CIG75_RS07795 4511d3aba78592d433cc6443149d91d0 267 Gene3D G3DSA:3.40.50.1860 3 115 4.4E-23 T 28-03-2018 CIG75_RS07795 4511d3aba78592d433cc6443149d91d0 267 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 71 79 - T 28-03-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CIG75_RS18680 c5c5929e9f7d22230ff5c01fc26d58d7 82 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 2 79 22.103 T 28-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CIG75_RS18680 c5c5929e9f7d22230ff5c01fc26d58d7 82 Gene3D G3DSA:3.30.1280.10 1 80 7.1E-31 T 28-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CIG75_RS18680 c5c5929e9f7d22230ff5c01fc26d58d7 82 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 9 81 3.0E-19 T 28-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CIG75_RS18680 c5c5929e9f7d22230ff5c01fc26d58d7 82 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 4 79 1.1E-33 T 28-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CIG75_RS18680 c5c5929e9f7d22230ff5c01fc26d58d7 82 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 3 79 2.1E-32 T 28-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CIG75_RS18680 c5c5929e9f7d22230ff5c01fc26d58d7 82 SUPERFAMILY SSF82697 3 79 1.74E-28 T 28-03-2018 CIG75_RS13650 e0547f0cc2ba2a655155fa2cee57a33a 635 Pfam PF16326 ABC transporter C-terminal domain 577 634 6.3E-8 T 28-03-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 CIG75_RS13650 e0547f0cc2ba2a655155fa2cee57a33a 635 Pfam PF12848 ABC transporter 233 322 1.6E-20 T 28-03-2018 IPR032781 ABC-transporter extension domain CIG75_RS13650 e0547f0cc2ba2a655155fa2cee57a33a 635 ProSitePatterns PS00211 ABC transporters family signature. 453 467 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS13650 e0547f0cc2ba2a655155fa2cee57a33a 635 Gene3D G3DSA:3.40.50.300 299 561 2.4E-51 T 28-03-2018 CIG75_RS13650 e0547f0cc2ba2a655155fa2cee57a33a 635 SUPERFAMILY SSF52540 316 538 8.26E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS13650 e0547f0cc2ba2a655155fa2cee57a33a 635 SUPERFAMILY SSF52540 5 240 2.24E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS13650 e0547f0cc2ba2a655155fa2cee57a33a 635 ProSitePatterns PS00211 ABC transporters family signature. 166 180 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS13650 e0547f0cc2ba2a655155fa2cee57a33a 635 SMART SM00382 361 525 3.1E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS13650 e0547f0cc2ba2a655155fa2cee57a33a 635 SMART SM00382 27 239 7.6E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS13650 e0547f0cc2ba2a655155fa2cee57a33a 635 Pfam PF00005 ABC transporter 18 194 6.3E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS13650 e0547f0cc2ba2a655155fa2cee57a33a 635 Pfam PF00005 ABC transporter 355 481 1.4E-22 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS13650 e0547f0cc2ba2a655155fa2cee57a33a 635 Gene3D G3DSA:3.40.50.300 1 298 1.4E-50 T 28-03-2018 CIG75_RS14880 4caac45519992db5e5bc897575e259de 346 Pfam PF03418 Germination protease 282 345 2.3E-22 T 28-03-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 CIG75_RS14880 4caac45519992db5e5bc897575e259de 346 Pfam PF03418 Germination protease 33 274 9.1E-96 T 28-03-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 CIG75_RS14880 4caac45519992db5e5bc897575e259de 346 PIRSF PIRSF019549 275 346 1.1E-21 T 28-03-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 CIG75_RS14880 4caac45519992db5e5bc897575e259de 346 PIRSF PIRSF019549 17 285 3.1E-107 T 28-03-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 CIG75_RS14880 4caac45519992db5e5bc897575e259de 346 Gene3D G3DSA:3.40.50.1450 22 342 3.6E-119 T 28-03-2018 IPR023430 Peptidase HybD-like domain CIG75_RS14880 4caac45519992db5e5bc897575e259de 346 SUPERFAMILY SSF53163 18 346 2.09E-112 T 28-03-2018 IPR023430 Peptidase HybD-like domain CIG75_RS14880 4caac45519992db5e5bc897575e259de 346 ProDom PD041835 PROTEASE GERMINATION HYDROLASE SPORE GPR ENDOPEPTIDASE PROTEINASE ZYMOGEN PRECURSOR PEPTIDASE 24 346 9.0E-86 T 28-03-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 CIG75_RS14880 4caac45519992db5e5bc897575e259de 346 Hamap MF_00626 Germination protease [gpr]. 8 346 142.753 T 28-03-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 CIG75_RS14880 4caac45519992db5e5bc897575e259de 346 TIGRFAM TIGR01441 GPR: GPR endopeptidase 24 277 4.3E-97 T 28-03-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 CIG75_RS10045 159687582646b6a8be4a3404101f2cb5 223 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 89 159 1.0E-5 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CIG75_RS10045 159687582646b6a8be4a3404101f2cb5 223 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 70 184 7.0E-20 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CIG75_RS10045 159687582646b6a8be4a3404101f2cb5 223 Gene3D G3DSA:1.10.150.240 28 78 3.9E-6 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CIG75_RS10045 159687582646b6a8be4a3404101f2cb5 223 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 183 4.8E-35 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS10045 159687582646b6a8be4a3404101f2cb5 223 SUPERFAMILY SSF56784 1 209 5.38E-51 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS10045 159687582646b6a8be4a3404101f2cb5 223 Gene3D G3DSA:3.40.50.1000 79 222 5.6E-33 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS10045 159687582646b6a8be4a3404101f2cb5 223 Gene3D G3DSA:3.40.50.1000 1 27 0.2 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS05985 51f28458772bb152ca7107f681291612 173 SUPERFAMILY SSF54364 6 79 7.32E-30 T 28-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CIG75_RS05985 51f28458772bb152ca7107f681291612 173 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 8 169 4.8E-72 T 28-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CIG75_RS05985 51f28458772bb152ca7107f681291612 173 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 1 171 31.118 T 28-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CIG75_RS05985 51f28458772bb152ca7107f681291612 173 ProSitePatterns PS00938 Initiation factor 3 signature. 59 72 - T 28-03-2018 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 CIG75_RS05985 51f28458772bb152ca7107f681291612 173 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 84 169 8.3E-38 T 28-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 CIG75_RS05985 51f28458772bb152ca7107f681291612 173 Gene3D G3DSA:3.10.20.80 3 79 1.1E-34 T 28-03-2018 CIG75_RS05985 51f28458772bb152ca7107f681291612 173 Gene3D G3DSA:3.30.110.10 80 173 4.5E-33 T 28-03-2018 CIG75_RS05985 51f28458772bb152ca7107f681291612 173 SUPERFAMILY SSF55200 83 169 8.37E-32 T 28-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 CIG75_RS05985 51f28458772bb152ca7107f681291612 173 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 8 77 2.3E-34 T 28-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CIG75_RS11980 217dba8f3038e104f1ceabdc044cd9c3 89 PIRSF PIRSF004669 1 89 1.2E-32 T 28-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 CIG75_RS11980 217dba8f3038e104f1ceabdc044cd9c3 89 Pfam PF01313 Bacterial export proteins, family 3 6 77 1.8E-29 T 28-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 CIG75_RS11980 217dba8f3038e104f1ceabdc044cd9c3 89 TIGRFAM TIGR01402 fliQ: flagellar biosynthetic protein FliQ 3 87 1.0E-30 T 28-03-2018 IPR006305 Flagellar biosynthesis protein FliQ GO:0016021|GO:0044780 CIG75_RS11980 217dba8f3038e104f1ceabdc044cd9c3 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 39 54 2.7E-21 T 28-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 CIG75_RS11980 217dba8f3038e104f1ceabdc044cd9c3 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 18 39 2.7E-21 T 28-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 CIG75_RS11980 217dba8f3038e104f1ceabdc044cd9c3 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 54 76 2.7E-21 T 28-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 CIG75_RS02725 f64d7dab96f1e07ddeeb6860e01b9f85 106 SUPERFAMILY SSF46785 10 100 1.52E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS02725 f64d7dab96f1e07ddeeb6860e01b9f85 106 Gene3D G3DSA:1.10.10.10 1 93 8.4E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS02725 f64d7dab96f1e07ddeeb6860e01b9f85 106 Pfam PF03551 Transcriptional regulator PadR-like family 14 82 5.5E-21 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal CIG75_RS18095 e1874089bd36f6cb30f738d298c00485 402 SUPERFAMILY SSF53901 3 275 1.28E-87 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS18095 e1874089bd36f6cb30f738d298c00485 402 Gene3D G3DSA:3.40.47.10 1 274 3.3E-65 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS18095 e1874089bd36f6cb30f738d298c00485 402 Pfam PF02803 Thiolase, C-terminal domain 276 397 1.1E-49 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CIG75_RS18095 e1874089bd36f6cb30f738d298c00485 402 ProSitePatterns PS00737 Thiolases signature 2. 344 360 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CIG75_RS18095 e1874089bd36f6cb30f738d298c00485 402 PIRSF PIRSF000429 1 399 9.3E-139 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CIG75_RS18095 e1874089bd36f6cb30f738d298c00485 402 Gene3D G3DSA:3.40.47.10 275 395 1.4E-35 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS18095 e1874089bd36f6cb30f738d298c00485 402 ProSitePatterns PS00099 Thiolases active site. 379 392 - T 28-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 CIG75_RS18095 e1874089bd36f6cb30f738d298c00485 402 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 85 103 - T 28-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 CIG75_RS18095 e1874089bd36f6cb30f738d298c00485 402 Pfam PF00108 Thiolase, N-terminal domain 5 267 6.2E-85 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CIG75_RS18095 e1874089bd36f6cb30f738d298c00485 402 SUPERFAMILY SSF53901 276 397 3.61E-45 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS18095 e1874089bd36f6cb30f738d298c00485 402 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 396 1.5E-147 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CIG75_RS17345 b9c770f1cd03eff81166d7fd91315f0e 214 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 6 175 6.8E-10 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CIG75_RS17345 b9c770f1cd03eff81166d7fd91315f0e 214 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 143 163 1.5E-9 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CIG75_RS17345 b9c770f1cd03eff81166d7fd91315f0e 214 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 94 107 1.5E-9 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CIG75_RS17345 b9c770f1cd03eff81166d7fd91315f0e 214 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 1.5E-9 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CIG75_RS17345 b9c770f1cd03eff81166d7fd91315f0e 214 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 125 141 1.5E-9 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CIG75_RS17345 b9c770f1cd03eff81166d7fd91315f0e 214 Gene3D G3DSA:1.10.150.240 28 73 2.2E-13 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CIG75_RS17345 b9c770f1cd03eff81166d7fd91315f0e 214 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 181 3.1E-51 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS17345 b9c770f1cd03eff81166d7fd91315f0e 214 Gene3D G3DSA:3.40.50.1000 74 214 4.7E-37 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS17345 b9c770f1cd03eff81166d7fd91315f0e 214 Gene3D G3DSA:3.40.50.1000 1 27 0.018 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS17345 b9c770f1cd03eff81166d7fd91315f0e 214 SUPERFAMILY SSF56784 1 212 1.25E-61 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS17345 b9c770f1cd03eff81166d7fd91315f0e 214 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 85 179 4.6E-11 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CIG75_RS09765 ab245d41f1724d93295a1dba5236eb04 107 SUPERFAMILY SSF54909 4 106 1.77E-34 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CIG75_RS09765 ab245d41f1724d93295a1dba5236eb04 107 Pfam PF03992 Antibiotic biosynthesis monooxygenase 35 83 1.2E-6 T 28-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain CIG75_RS09765 ab245d41f1724d93295a1dba5236eb04 107 Gene3D G3DSA:3.30.70.100 10 101 1.7E-23 T 28-03-2018 CIG75_RS16680 b957dababc7ed424ab0f38deaf8d3aa3 590 Gene3D G3DSA:3.40.50.300 334 586 4.4E-72 T 28-03-2018 CIG75_RS16680 b957dababc7ed424ab0f38deaf8d3aa3 590 ProSitePatterns PS00211 ABC transporters family signature. 483 497 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS16680 b957dababc7ed424ab0f38deaf8d3aa3 590 Gene3D G3DSA:1.20.1560.10 7 333 3.2E-42 T 28-03-2018 CIG75_RS16680 b957dababc7ed424ab0f38deaf8d3aa3 590 SUPERFAMILY SSF90123 11 318 1.83E-49 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CIG75_RS16680 b957dababc7ed424ab0f38deaf8d3aa3 590 Pfam PF00664 ABC transporter transmembrane region 31 293 6.9E-26 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CIG75_RS16680 b957dababc7ed424ab0f38deaf8d3aa3 590 Pfam PF00005 ABC transporter 362 510 1.4E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS16680 b957dababc7ed424ab0f38deaf8d3aa3 590 SMART SM00382 371 557 1.8E-19 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS16680 b957dababc7ed424ab0f38deaf8d3aa3 590 SUPERFAMILY SSF52540 335 579 3.29E-84 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS18145 59799f6ccff6e4dfc6aeede6a661b678 152 Pfam PF01381 Helix-turn-helix 31 86 1.3E-14 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS18145 59799f6ccff6e4dfc6aeede6a661b678 152 Gene3D G3DSA:1.10.260.40 4 97 1.3E-20 T 28-03-2018 CIG75_RS18145 59799f6ccff6e4dfc6aeede6a661b678 152 SMART SM00530 30 86 3.1E-16 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS18145 59799f6ccff6e4dfc6aeede6a661b678 152 SUPERFAMILY SSF47413 25 91 7.04E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CIG75_RS11430 5930394191597c8311f22e9674f1b435 183 Pfam PF08864 UPF0302 domain 9 112 5.0E-38 T 28-03-2018 IPR014963 Uncharacterised domain UPF0302, N-terminal CIG75_RS11430 5930394191597c8311f22e9674f1b435 183 SMART SM00914 139 175 5.0E-10 T 28-03-2018 IPR014957 IDEAL domain CIG75_RS11430 5930394191597c8311f22e9674f1b435 183 PIRSF PIRSF007165 1 180 6.2E-53 T 28-03-2018 IPR011188 Uncharacterised protein family UPF0302 CIG75_RS11430 5930394191597c8311f22e9674f1b435 183 Hamap MF_00760 UPF0302 protein . 2 178 24.312 T 28-03-2018 IPR011188 Uncharacterised protein family UPF0302 CIG75_RS11430 5930394191597c8311f22e9674f1b435 183 Pfam PF08858 IDEAL domain 139 175 2.2E-12 T 28-03-2018 IPR014957 IDEAL domain CIG75_RS19640 c1a15dcada9c9fccbc3ee436254864c9 147 Gene3D G3DSA:3.100.10.10 42 147 4.5E-32 T 28-03-2018 CIG75_RS19640 c1a15dcada9c9fccbc3ee436254864c9 147 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 28 145 4.6E-38 T 28-03-2018 IPR021131 Ribosomal protein L18e/L15P CIG75_RS19640 c1a15dcada9c9fccbc3ee436254864c9 147 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 2 144 1.5E-53 T 28-03-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS19640 c1a15dcada9c9fccbc3ee436254864c9 147 ProSitePatterns PS00475 Ribosomal protein L15 signature. 111 141 - T 28-03-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CIG75_RS19640 c1a15dcada9c9fccbc3ee436254864c9 147 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 3 147 22.509 T 28-03-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 CIG75_RS19640 c1a15dcada9c9fccbc3ee436254864c9 147 SUPERFAMILY SSF52080 4 146 6.8E-51 T 28-03-2018 IPR021131 Ribosomal protein L18e/L15P CIG75_RS19620 06a38a29d9003f2055e4b24b52659bd9 88 SUPERFAMILY SSF50104 9 63 1.2E-9 T 28-03-2018 IPR008991 Translation protein SH3-like domain CIG75_RS19620 06a38a29d9003f2055e4b24b52659bd9 88 Gene3D G3DSA:2.30.30.30 7 83 2.9E-8 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 CIG75_RS19500 927bf9e94dad9fa832a0ebab61906b52 813 Pfam PF07517 SecA DEAD-like domain 5 383 7.0E-131 T 28-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 CIG75_RS19500 927bf9e94dad9fa832a0ebab61906b52 813 SUPERFAMILY SSF52540 398 570 1.68E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS19500 927bf9e94dad9fa832a0ebab61906b52 813 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 27 498 9.3E-241 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CIG75_RS19500 927bf9e94dad9fa832a0ebab61906b52 813 SMART SM00957 5 383 4.5E-287 T 28-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 CIG75_RS19500 927bf9e94dad9fa832a0ebab61906b52 813 ProSitePatterns PS01312 SecA family signature. 481 496 - T 28-03-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 CIG75_RS19500 927bf9e94dad9fa832a0ebab61906b52 813 Gene3D G3DSA:3.40.50.300 8 270 6.2E-54 T 28-03-2018 CIG75_RS19500 927bf9e94dad9fa832a0ebab61906b52 813 Gene3D G3DSA:3.40.50.300 282 397 2.1E-8 T 28-03-2018 CIG75_RS19500 927bf9e94dad9fa832a0ebab61906b52 813 Hamap MF_01382 Protein translocase subunit SecA [secA]. 4 782 20.041 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CIG75_RS19500 927bf9e94dad9fa832a0ebab61906b52 813 PRINTS PR00906 SecA protein signature 320 342 6.2E-71 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CIG75_RS19500 927bf9e94dad9fa832a0ebab61906b52 813 PRINTS PR00906 SecA protein signature 100 114 6.2E-71 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CIG75_RS19500 927bf9e94dad9fa832a0ebab61906b52 813 PRINTS PR00906 SecA protein signature 357 374 6.2E-71 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CIG75_RS19500 927bf9e94dad9fa832a0ebab61906b52 813 PRINTS PR00906 SecA protein signature 116 126 6.2E-71 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CIG75_RS19500 927bf9e94dad9fa832a0ebab61906b52 813 PRINTS PR00906 SecA protein signature 62 86 6.2E-71 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CIG75_RS19500 927bf9e94dad9fa832a0ebab61906b52 813 PRINTS PR00906 SecA protein signature 169 189 6.2E-71 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CIG75_RS19500 927bf9e94dad9fa832a0ebab61906b52 813 PRINTS PR00906 SecA protein signature 394 407 6.2E-71 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CIG75_RS19500 927bf9e94dad9fa832a0ebab61906b52 813 Pfam PF07516 SecA Wing and Scaffold domain 569 779 4.2E-67 T 28-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CIG75_RS19500 927bf9e94dad9fa832a0ebab61906b52 813 SUPERFAMILY SSF81767 226 349 1.23E-46 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CIG75_RS19500 927bf9e94dad9fa832a0ebab61906b52 813 SMART SM00958 227 339 5.3E-65 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CIG75_RS19500 927bf9e94dad9fa832a0ebab61906b52 813 Gene3D G3DSA:3.10.450.50 681 809 8.1E-26 T 28-03-2018 CIG75_RS19500 927bf9e94dad9fa832a0ebab61906b52 813 Pfam PF00271 Helicase conserved C-terminal domain 416 531 2.3E-5 T 28-03-2018 IPR001650 Helicase, C-terminal CIG75_RS19500 927bf9e94dad9fa832a0ebab61906b52 813 Pfam PF01043 SecA preprotein cross-linking domain 231 339 2.1E-39 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CIG75_RS19500 927bf9e94dad9fa832a0ebab61906b52 813 SUPERFAMILY SSF81886 574 781 1.57E-73 T 28-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CIG75_RS19500 927bf9e94dad9fa832a0ebab61906b52 813 SUPERFAMILY SSF52540 4 227 8.55E-85 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS19500 927bf9e94dad9fa832a0ebab61906b52 813 SUPERFAMILY SSF52540 349 396 8.55E-85 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS19500 927bf9e94dad9fa832a0ebab61906b52 813 Gene3D G3DSA:1.10.3060.10 586 680 4.6E-32 T 28-03-2018 CIG75_RS19500 927bf9e94dad9fa832a0ebab61906b52 813 Gene3D G3DSA:3.40.50.300 398 585 8.4E-56 T 28-03-2018 CIG75_RS19820 42b33f32266015ddb9675aa01a809a19 170 Pfam PF05991 YacP-like NYN domain 5 169 1.1E-50 T 28-03-2018 IPR010298 Protein of unknown function DUF901 CIG75_RS01440 0a167f28889a13573ebd4fc99ae5b49e 292 PIRSF PIRSF036979 1 290 3.5E-88 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 CIG75_RS01440 0a167f28889a13573ebd4fc99ae5b49e 292 Pfam PF00491 Arginase family 23 285 9.0E-75 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 CIG75_RS01440 0a167f28889a13573ebd4fc99ae5b49e 292 ProSitePatterns PS01053 Arginase family signature. 213 234 - T 28-03-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 CIG75_RS01440 0a167f28889a13573ebd4fc99ae5b49e 292 TIGRFAM TIGR01230 agmatinase: agmatinase 11 285 1.0E-97 T 28-03-2018 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 CIG75_RS01440 0a167f28889a13573ebd4fc99ae5b49e 292 Gene3D G3DSA:3.40.800.10 15 292 6.4E-79 T 28-03-2018 CIG75_RS01440 0a167f28889a13573ebd4fc99ae5b49e 292 PRINTS PR00116 Arginase signature 73 88 3.6E-9 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 CIG75_RS01440 0a167f28889a13573ebd4fc99ae5b49e 292 PRINTS PR00116 Arginase signature 210 239 3.6E-9 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 CIG75_RS01440 0a167f28889a13573ebd4fc99ae5b49e 292 SUPERFAMILY SSF52768 13 287 1.15E-80 T 28-03-2018 CIG75_RS17470 cb27fd02d1bb303af917367ffbc5b1e7 242 SMART SM00382 92 224 2.0E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS17470 cb27fd02d1bb303af917367ffbc5b1e7 242 PIRSF PIRSF003073 1 242 9.8E-75 T 28-03-2018 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein CIG75_RS17470 cb27fd02d1bb303af917367ffbc5b1e7 242 SUPERFAMILY SSF52540 67 223 2.64E-26 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS17470 cb27fd02d1bb303af917367ffbc5b1e7 242 Pfam PF01695 IstB-like ATP binding protein 49 223 1.3E-59 T 28-03-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 CIG75_RS17470 cb27fd02d1bb303af917367ffbc5b1e7 242 Gene3D G3DSA:3.40.50.300 33 222 9.2E-15 T 28-03-2018 CIG75_RS02645 cb27fd02d1bb303af917367ffbc5b1e7 242 SMART SM00382 92 224 2.0E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS02645 cb27fd02d1bb303af917367ffbc5b1e7 242 PIRSF PIRSF003073 1 242 9.8E-75 T 28-03-2018 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein CIG75_RS02645 cb27fd02d1bb303af917367ffbc5b1e7 242 SUPERFAMILY SSF52540 67 223 2.64E-26 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS02645 cb27fd02d1bb303af917367ffbc5b1e7 242 Pfam PF01695 IstB-like ATP binding protein 49 223 1.3E-59 T 28-03-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 CIG75_RS02645 cb27fd02d1bb303af917367ffbc5b1e7 242 Gene3D G3DSA:3.40.50.300 33 222 9.2E-15 T 28-03-2018 CIG75_RS03935 cb27fd02d1bb303af917367ffbc5b1e7 242 SMART SM00382 92 224 2.0E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS03935 cb27fd02d1bb303af917367ffbc5b1e7 242 PIRSF PIRSF003073 1 242 9.8E-75 T 28-03-2018 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein CIG75_RS03935 cb27fd02d1bb303af917367ffbc5b1e7 242 SUPERFAMILY SSF52540 67 223 2.64E-26 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS03935 cb27fd02d1bb303af917367ffbc5b1e7 242 Pfam PF01695 IstB-like ATP binding protein 49 223 1.3E-59 T 28-03-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 CIG75_RS03935 cb27fd02d1bb303af917367ffbc5b1e7 242 Gene3D G3DSA:3.40.50.300 33 222 9.2E-15 T 28-03-2018 CIG75_RS09460 cb27fd02d1bb303af917367ffbc5b1e7 242 SMART SM00382 92 224 2.0E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS09460 cb27fd02d1bb303af917367ffbc5b1e7 242 PIRSF PIRSF003073 1 242 9.8E-75 T 28-03-2018 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein CIG75_RS09460 cb27fd02d1bb303af917367ffbc5b1e7 242 SUPERFAMILY SSF52540 67 223 2.64E-26 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS09460 cb27fd02d1bb303af917367ffbc5b1e7 242 Pfam PF01695 IstB-like ATP binding protein 49 223 1.3E-59 T 28-03-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 CIG75_RS09460 cb27fd02d1bb303af917367ffbc5b1e7 242 Gene3D G3DSA:3.40.50.300 33 222 9.2E-15 T 28-03-2018 CIG75_RS00815 cb27fd02d1bb303af917367ffbc5b1e7 242 SMART SM00382 92 224 2.0E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS00815 cb27fd02d1bb303af917367ffbc5b1e7 242 PIRSF PIRSF003073 1 242 9.8E-75 T 28-03-2018 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein CIG75_RS00815 cb27fd02d1bb303af917367ffbc5b1e7 242 SUPERFAMILY SSF52540 67 223 2.64E-26 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS00815 cb27fd02d1bb303af917367ffbc5b1e7 242 Pfam PF01695 IstB-like ATP binding protein 49 223 1.3E-59 T 28-03-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 CIG75_RS00815 cb27fd02d1bb303af917367ffbc5b1e7 242 Gene3D G3DSA:3.40.50.300 33 222 9.2E-15 T 28-03-2018 CIG75_RS20240 d2f0c441749ed24db247bf6805adbbee 492 Gene3D G3DSA:3.40.1010.10 6 128 7.8E-16 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CIG75_RS20240 d2f0c441749ed24db247bf6805adbbee 492 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 265 338 1.3E-26 T 28-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core CIG75_RS20240 d2f0c441749ed24db247bf6805adbbee 492 SUPERFAMILY SSF101386 242 340 2.62E-21 T 28-03-2018 CIG75_RS20240 d2f0c441749ed24db247bf6805adbbee 492 Gene3D G3DSA:1.10.287.1080 241 361 6.3E-36 T 28-03-2018 CIG75_RS20240 d2f0c441749ed24db247bf6805adbbee 492 SUPERFAMILY SSF101386 377 470 2.99E-20 T 28-03-2018 CIG75_RS20240 d2f0c441749ed24db247bf6805adbbee 492 TIGRFAM TIGR00444 mazG: MazG family protein 248 490 6.1E-93 T 28-03-2018 IPR011551 NTP pyrophosphohydrolase MazG CIG75_RS20240 d2f0c441749ed24db247bf6805adbbee 492 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 7 215 1.9E-21 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CIG75_RS20240 d2f0c441749ed24db247bf6805adbbee 492 Gene3D G3DSA:1.10.287.1080 378 492 2.1E-20 T 28-03-2018 CIG75_RS20240 d2f0c441749ed24db247bf6805adbbee 492 SUPERFAMILY SSF53790 7 232 4.8E-25 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CIG75_RS20240 d2f0c441749ed24db247bf6805adbbee 492 PIRSF PIRSF002845 4 492 5.2E-179 T 28-03-2018 IPR024180 Bifunctional tetrapyrrole methylase/MazG NTP pyrophosphohydrolase, predicted CIG75_RS14340 7a1c76eae67f4be2fefd0e9ea7651d0c 749 SMART SM00382 477 710 0.0018 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS14340 7a1c76eae67f4be2fefd0e9ea7651d0c 749 SMART SM00382 25 414 2.2 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS14340 7a1c76eae67f4be2fefd0e9ea7651d0c 749 SUPERFAMILY SSF52540 460 724 2.62E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS14340 7a1c76eae67f4be2fefd0e9ea7651d0c 749 ProSitePatterns PS00211 ABC transporters family signature. 644 658 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS14340 7a1c76eae67f4be2fefd0e9ea7651d0c 749 Gene3D G3DSA:3.40.50.300 1 90 0.014 T 28-03-2018 CIG75_RS14340 7a1c76eae67f4be2fefd0e9ea7651d0c 749 SUPERFAMILY SSF52540 5 192 8.69E-33 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS14340 7a1c76eae67f4be2fefd0e9ea7651d0c 749 SUPERFAMILY SSF52540 288 427 8.69E-33 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS14340 7a1c76eae67f4be2fefd0e9ea7651d0c 749 Gene3D G3DSA:1.20.1580.10 95 125 1.4E-6 T 28-03-2018 CIG75_RS14340 7a1c76eae67f4be2fefd0e9ea7651d0c 749 Gene3D G3DSA:1.20.1580.10 126 337 5.4E-42 T 28-03-2018 CIG75_RS14340 7a1c76eae67f4be2fefd0e9ea7651d0c 749 Gene3D G3DSA:3.40.50.300 453 749 3.7E-56 T 28-03-2018 CIG75_RS14340 7a1c76eae67f4be2fefd0e9ea7651d0c 749 Pfam PF00005 ABC transporter 468 671 5.3E-13 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS09870 5c65f2bceef7b64eb1fbf0d2f275a476 286 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 164 284 2.7E-23 T 28-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 CIG75_RS09870 5c65f2bceef7b64eb1fbf0d2f275a476 286 SUPERFAMILY SSF48179 164 284 2.49E-21 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CIG75_RS09870 5c65f2bceef7b64eb1fbf0d2f275a476 286 SUPERFAMILY SSF51735 3 162 1.88E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS09870 5c65f2bceef7b64eb1fbf0d2f275a476 286 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 4 161 2.8E-35 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CIG75_RS09870 5c65f2bceef7b64eb1fbf0d2f275a476 286 Gene3D G3DSA:3.40.50.720 1 162 5.2E-29 T 28-03-2018 CIG75_RS09870 5c65f2bceef7b64eb1fbf0d2f275a476 286 PIRSF PIRSF000103 1 284 1.0E-53 T 28-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CIG75_RS09870 5c65f2bceef7b64eb1fbf0d2f275a476 286 Gene3D G3DSA:1.10.1040.10 163 285 7.6E-19 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CIG75_RS06050 f11d70c71db4c92b38f2db48f8524baf 452 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 55 450 6.9E-132 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CIG75_RS06050 f11d70c71db4c92b38f2db48f8524baf 452 Pfam PF00579 tRNA synthetases class I (W and Y) 85 372 3.5E-80 T 28-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 CIG75_RS06050 f11d70c71db4c92b38f2db48f8524baf 452 Gene3D G3DSA:3.40.50.620 49 272 4.7E-65 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CIG75_RS06050 f11d70c71db4c92b38f2db48f8524baf 452 SUPERFAMILY SSF52374 57 371 1.42E-97 T 28-03-2018 CIG75_RS06050 f11d70c71db4c92b38f2db48f8524baf 452 SMART SM00363 390 450 3.0E-5 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CIG75_RS06050 f11d70c71db4c92b38f2db48f8524baf 452 Hamap MF_02007 Tyrosine--tRNA ligase [tyrS]. 52 451 48.863 T 28-03-2018 IPR024108 Tyrosine-tRNA ligase, bacterial-type, type 2 GO:0004831 KEGG: 00970+6.1.1.1 CIG75_RS06050 f11d70c71db4c92b38f2db48f8524baf 452 SUPERFAMILY SSF55174 353 450 3.27E-21 T 28-03-2018 CIG75_RS06050 f11d70c71db4c92b38f2db48f8524baf 452 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 100 122 2.2E-25 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CIG75_RS06050 f11d70c71db4c92b38f2db48f8524baf 452 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 215 230 2.2E-25 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CIG75_RS06050 f11d70c71db4c92b38f2db48f8524baf 452 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 265 277 2.2E-25 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CIG75_RS06050 f11d70c71db4c92b38f2db48f8524baf 452 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 232 254 2.2E-25 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CIG75_RS06050 f11d70c71db4c92b38f2db48f8524baf 452 Pfam PF01479 S4 domain 391 425 7.4E-8 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CIG75_RS06050 f11d70c71db4c92b38f2db48f8524baf 452 Gene3D G3DSA:1.10.240.10 273 364 5.2E-29 T 28-03-2018 CIG75_RS06050 f11d70c71db4c92b38f2db48f8524baf 452 Gene3D G3DSA:3.10.290.10 365 452 2.0E-25 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CIG75_RS06050 f11d70c71db4c92b38f2db48f8524baf 452 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 96 106 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CIG75_RS08745 7a7d0a0d74a4c2ee5e1b2fa82a509010 765 Gene3D G3DSA:3.30.870.10 441 619 5.9E-23 T 28-03-2018 CIG75_RS08745 7a7d0a0d74a4c2ee5e1b2fa82a509010 765 SUPERFAMILY SSF74853 618 728 6.54E-15 T 28-03-2018 IPR001322 Lamin Tail Domain CIG75_RS08745 7a7d0a0d74a4c2ee5e1b2fa82a509010 765 Gene3D G3DSA:3.30.870.10 197 388 5.8E-21 T 28-03-2018 CIG75_RS08745 7a7d0a0d74a4c2ee5e1b2fa82a509010 765 SUPERFAMILY SSF56024 447 604 2.38E-19 T 28-03-2018 CIG75_RS08745 7a7d0a0d74a4c2ee5e1b2fa82a509010 765 SUPERFAMILY SSF74853 52 108 1.7E-7 T 28-03-2018 IPR001322 Lamin Tail Domain CIG75_RS08745 7a7d0a0d74a4c2ee5e1b2fa82a509010 765 Gene3D G3DSA:2.60.40.1260 26 169 1.1E-18 T 28-03-2018 IPR001322 Lamin Tail Domain CIG75_RS08745 7a7d0a0d74a4c2ee5e1b2fa82a509010 765 Pfam PF13091 PLD-like domain 452 601 5.9E-18 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CIG75_RS08745 7a7d0a0d74a4c2ee5e1b2fa82a509010 765 Pfam PF13091 PLD-like domain 243 382 7.1E-14 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CIG75_RS08745 7a7d0a0d74a4c2ee5e1b2fa82a509010 765 SUPERFAMILY SSF56024 216 388 1.14E-23 T 28-03-2018 CIG75_RS08745 7a7d0a0d74a4c2ee5e1b2fa82a509010 765 Gene3D G3DSA:2.60.40.1260 620 729 2.9E-19 T 28-03-2018 IPR001322 Lamin Tail Domain CIG75_RS08745 7a7d0a0d74a4c2ee5e1b2fa82a509010 765 Pfam PF00932 Lamin Tail Domain 40 162 5.6E-16 T 28-03-2018 IPR001322 Lamin Tail Domain CIG75_RS08745 7a7d0a0d74a4c2ee5e1b2fa82a509010 765 Pfam PF00932 Lamin Tail Domain 615 725 1.8E-19 T 28-03-2018 IPR001322 Lamin Tail Domain CIG75_RS00750 5d74a9f3a734af9a9a75cbcf4bb0f85a 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 115 135 1.2E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CIG75_RS00750 5d74a9f3a734af9a9a75cbcf4bb0f85a 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 49 65 1.2E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CIG75_RS00750 5d74a9f3a734af9a9a75cbcf4bb0f85a 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 85 101 1.2E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CIG75_RS00750 5d74a9f3a734af9a9a75cbcf4bb0f85a 147 SUPERFAMILY SSF46785 9 137 1.62E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS00750 5d74a9f3a734af9a9a75cbcf4bb0f85a 147 Gene3D G3DSA:1.10.287.100 104 142 2.2E-7 T 28-03-2018 CIG75_RS00750 5d74a9f3a734af9a9a75cbcf4bb0f85a 147 Gene3D G3DSA:1.10.10.10 1 103 1.2E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS00750 5d74a9f3a734af9a9a75cbcf4bb0f85a 147 Pfam PF12802 MarR family 33 88 7.8E-10 T 28-03-2018 CIG75_RS00750 5d74a9f3a734af9a9a75cbcf4bb0f85a 147 SMART SM00347 25 125 6.1E-16 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CIG75_RS03835 a354a9ae5c71518bd7985a1072f7064e 481 SUPERFAMILY SSF55931 9 300 1.18E-122 T 28-03-2018 CIG75_RS03835 a354a9ae5c71518bd7985a1072f7064e 481 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 7 479 4.5E-190 T 28-03-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 CIG75_RS03835 a354a9ae5c71518bd7985a1072f7064e 481 SMART SM00845 332 479 6.7E-81 T 28-03-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 CIG75_RS03835 a354a9ae5c71518bd7985a1072f7064e 481 Pfam PF02934 GatB/GatE catalytic domain 11 293 1.7E-115 T 28-03-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 CIG75_RS03835 a354a9ae5c71518bd7985a1072f7064e 481 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 7 480 39.804 T 28-03-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 CIG75_RS03835 a354a9ae5c71518bd7985a1072f7064e 481 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 148 162 - T 28-03-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 CIG75_RS03835 a354a9ae5c71518bd7985a1072f7064e 481 Gene3D G3DSA:1.10.10.410 419 480 1.7E-24 T 28-03-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal CIG75_RS03835 a354a9ae5c71518bd7985a1072f7064e 481 SUPERFAMILY SSF89095 301 407 1.44E-35 T 28-03-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 CIG75_RS03835 a354a9ae5c71518bd7985a1072f7064e 481 Pfam PF02637 GatB domain 332 479 2.8E-57 T 28-03-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 CIG75_RS10110 916eca2a5f526bfb6b92b0e7628b00ef 1085 SUPERFAMILY SSF48452 576 718 2.23E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS10110 916eca2a5f526bfb6b92b0e7628b00ef 1085 Gene3D G3DSA:1.25.40.10 926 1081 7.6E-20 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS10110 916eca2a5f526bfb6b92b0e7628b00ef 1085 Gene3D G3DSA:1.25.40.10 324 567 7.2E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS10110 916eca2a5f526bfb6b92b0e7628b00ef 1085 SUPERFAMILY SSF48452 416 529 4.17E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS10110 916eca2a5f526bfb6b92b0e7628b00ef 1085 SUPERFAMILY SSF48452 615 645 4.17E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS10110 916eca2a5f526bfb6b92b0e7628b00ef 1085 SMART SM01043 929 1073 9.5E-43 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CIG75_RS10110 916eca2a5f526bfb6b92b0e7628b00ef 1085 Pfam PF03704 Bacterial transcriptional activator domain 929 1072 4.0E-24 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CIG75_RS10110 916eca2a5f526bfb6b92b0e7628b00ef 1085 SUPERFAMILY SSF46894 828 902 2.83E-5 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CIG75_RS10110 916eca2a5f526bfb6b92b0e7628b00ef 1085 SUPERFAMILY SSF48452 927 1076 7.34E-25 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS10110 916eca2a5f526bfb6b92b0e7628b00ef 1085 Gene3D G3DSA:1.10.10.10 814 923 6.6E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS10110 916eca2a5f526bfb6b92b0e7628b00ef 1085 SMART SM00028 615 648 23.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS10110 916eca2a5f526bfb6b92b0e7628b00ef 1085 SMART SM00028 989 1022 26.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS10110 916eca2a5f526bfb6b92b0e7628b00ef 1085 SMART SM00028 496 529 430.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS10110 916eca2a5f526bfb6b92b0e7628b00ef 1085 SMART SM00028 1023 1056 210.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS10110 916eca2a5f526bfb6b92b0e7628b00ef 1085 Gene3D G3DSA:1.25.40.10 568 779 2.4E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS10110 916eca2a5f526bfb6b92b0e7628b00ef 1085 Pfam PF00486 Transcriptional regulatory protein, C terminal 849 901 1.6E-4 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CIG75_RS04690 a732675b4e3f1805dbfd1fbd31c97a0e 369 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS04690 a732675b4e3f1805dbfd1fbd31c97a0e 369 Pfam PF00005 ABC transporter 21 162 7.1E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS04690 a732675b4e3f1805dbfd1fbd31c97a0e 369 SUPERFAMILY SSF50331 237 368 8.5E-29 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CIG75_RS04690 a732675b4e3f1805dbfd1fbd31c97a0e 369 SMART SM00382 29 218 1.0E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS04690 a732675b4e3f1805dbfd1fbd31c97a0e 369 Gene3D G3DSA:2.40.50.140 298 353 4.5E-18 T 28-03-2018 CIG75_RS04690 a732675b4e3f1805dbfd1fbd31c97a0e 369 Pfam PF08402 TOBE domain 285 360 5.5E-10 T 28-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CIG75_RS04690 a732675b4e3f1805dbfd1fbd31c97a0e 369 SUPERFAMILY SSF52540 4 243 5.17E-87 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS04690 a732675b4e3f1805dbfd1fbd31c97a0e 369 Gene3D G3DSA:3.40.50.300 1 238 7.1E-70 T 28-03-2018 CIG75_RS04690 a732675b4e3f1805dbfd1fbd31c97a0e 369 Gene3D G3DSA:2.40.50.100 240 297 7.1E-14 T 28-03-2018 CIG75_RS17280 e3353db6e9c5615741008722c2e142e7 270 SMART SM00448 44 157 3.3E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CIG75_RS17280 e3353db6e9c5615741008722c2e142e7 270 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 202 216 2.2E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CIG75_RS17280 e3353db6e9c5615741008722c2e142e7 270 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 232 244 2.2E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CIG75_RS17280 e3353db6e9c5615741008722c2e142e7 270 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 216 232 2.2E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CIG75_RS17280 e3353db6e9c5615741008722c2e142e7 270 Pfam PF00072 Response regulator receiver domain 46 157 1.5E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CIG75_RS17280 e3353db6e9c5615741008722c2e142e7 270 SUPERFAMILY SSF52172 44 168 3.98E-32 T 28-03-2018 IPR011006 CheY-like superfamily CIG75_RS17280 e3353db6e9c5615741008722c2e142e7 270 Gene3D G3DSA:3.40.50.2300 43 175 1.1E-33 T 28-03-2018 CIG75_RS17280 e3353db6e9c5615741008722c2e142e7 270 SUPERFAMILY SSF46894 194 258 8.5E-18 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CIG75_RS17280 e3353db6e9c5615741008722c2e142e7 270 Pfam PF00196 Bacterial regulatory proteins, luxR family 202 255 3.5E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CIG75_RS17280 e3353db6e9c5615741008722c2e142e7 270 SMART SM00421 199 256 2.6E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CIG75_RS17280 e3353db6e9c5615741008722c2e142e7 270 Gene3D G3DSA:1.10.10.10 176 260 4.2E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS15985 018ccaf91b1d5330eae61b013bc06f12 446 SUPERFAMILY SSF103473 40 440 4.84E-45 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS15985 018ccaf91b1d5330eae61b013bc06f12 446 Gene3D G3DSA:1.20.1250.20 34 231 8.9E-27 T 28-03-2018 CIG75_RS15985 018ccaf91b1d5330eae61b013bc06f12 446 Pfam PF07690 Major Facilitator Superfamily 47 308 4.3E-23 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CIG75_RS15985 018ccaf91b1d5330eae61b013bc06f12 446 Gene3D G3DSA:1.20.1250.20 243 446 1.8E-11 T 28-03-2018 CIG75_RS11150 7d6dfaa44b459a7b4dc2a5d2ca5d1ab6 389 Gene3D G3DSA:1.20.1250.10 103 178 2.0E-9 T 28-03-2018 CIG75_RS11150 7d6dfaa44b459a7b4dc2a5d2ca5d1ab6 389 Gene3D G3DSA:1.10.260.40 14 102 3.1E-8 T 28-03-2018 CIG75_RS11150 7d6dfaa44b459a7b4dc2a5d2ca5d1ab6 389 Pfam PF13181 Tetratricopeptide repeat 166 189 0.21 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS11150 7d6dfaa44b459a7b4dc2a5d2ca5d1ab6 389 SUPERFAMILY SSF48452 144 310 1.9E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS11150 7d6dfaa44b459a7b4dc2a5d2ca5d1ab6 389 SMART SM00028 279 312 190.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS11150 7d6dfaa44b459a7b4dc2a5d2ca5d1ab6 389 SMART SM00028 242 275 7.1 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS11150 7d6dfaa44b459a7b4dc2a5d2ca5d1ab6 389 SMART SM00028 165 198 9.7 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS11150 7d6dfaa44b459a7b4dc2a5d2ca5d1ab6 389 SUPERFAMILY SSF47413 11 77 3.44E-7 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CIG75_RS11150 7d6dfaa44b459a7b4dc2a5d2ca5d1ab6 389 Gene3D G3DSA:1.25.40.10 179 383 1.7E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS05610 90bd932859de3eb17e00a9b67e1083c3 887 Gene3D G3DSA:1.10.150.20 187 265 1.4E-30 T 28-03-2018 CIG75_RS05610 90bd932859de3eb17e00a9b67e1083c3 887 SMART SM00279 175 210 7.1E-16 T 28-03-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 CIG75_RS05610 90bd932859de3eb17e00a9b67e1083c3 887 SMART SM00475 5 264 8.0E-139 T 28-03-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 CIG75_RS05610 90bd932859de3eb17e00a9b67e1083c3 887 SUPERFAMILY SSF47807 173 287 2.09E-33 T 28-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 CIG75_RS05610 90bd932859de3eb17e00a9b67e1083c3 887 ProSitePatterns PS00447 DNA polymerase family A signature. 713 732 - T 28-03-2018 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CIG75_RS05610 90bd932859de3eb17e00a9b67e1083c3 887 SMART SM00482 644 851 2.8E-116 T 28-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CIG75_RS05610 90bd932859de3eb17e00a9b67e1083c3 887 Gene3D G3DSA:3.30.420.10 299 499 1.5E-22 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CIG75_RS05610 90bd932859de3eb17e00a9b67e1083c3 887 SUPERFAMILY SSF88723 3 172 4.66E-55 T 28-03-2018 IPR029060 PIN domain-like CIG75_RS05610 90bd932859de3eb17e00a9b67e1083c3 887 Gene3D G3DSA:1.20.1060.10 500 614 9.4E-34 T 28-03-2018 CIG75_RS05610 90bd932859de3eb17e00a9b67e1083c3 887 Gene3D G3DSA:3.40.50.1010 5 186 1.3E-68 T 28-03-2018 IPR029060 PIN domain-like CIG75_RS05610 90bd932859de3eb17e00a9b67e1083c3 887 PRINTS PR00868 DNA-polymerase family A (pol I) signature 613 635 1.0E-78 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CIG75_RS05610 90bd932859de3eb17e00a9b67e1083c3 887 PRINTS PR00868 DNA-polymerase family A (pol I) signature 750 761 1.0E-78 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CIG75_RS05610 90bd932859de3eb17e00a9b67e1083c3 887 PRINTS PR00868 DNA-polymerase family A (pol I) signature 804 820 1.0E-78 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CIG75_RS05610 90bd932859de3eb17e00a9b67e1083c3 887 PRINTS PR00868 DNA-polymerase family A (pol I) signature 772 783 1.0E-78 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CIG75_RS05610 90bd932859de3eb17e00a9b67e1083c3 887 PRINTS PR00868 DNA-polymerase family A (pol I) signature 636 651 1.0E-78 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CIG75_RS05610 90bd932859de3eb17e00a9b67e1083c3 887 PRINTS PR00868 DNA-polymerase family A (pol I) signature 713 738 1.0E-78 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CIG75_RS05610 90bd932859de3eb17e00a9b67e1083c3 887 PRINTS PR00868 DNA-polymerase family A (pol I) signature 659 682 1.0E-78 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CIG75_RS05610 90bd932859de3eb17e00a9b67e1083c3 887 PRINTS PR00868 DNA-polymerase family A (pol I) signature 689 702 1.0E-78 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CIG75_RS05610 90bd932859de3eb17e00a9b67e1083c3 887 PRINTS PR00868 DNA-polymerase family A (pol I) signature 834 847 1.0E-78 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CIG75_RS05610 90bd932859de3eb17e00a9b67e1083c3 887 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 174 267 6.4E-34 T 28-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 CIG75_RS05610 90bd932859de3eb17e00a9b67e1083c3 887 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 6 172 3.1E-55 T 28-03-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 CIG75_RS05610 90bd932859de3eb17e00a9b67e1083c3 887 SUPERFAMILY SSF53098 314 475 3.19E-20 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CIG75_RS05610 90bd932859de3eb17e00a9b67e1083c3 887 SUPERFAMILY SSF56672 479 887 7.34E-158 T 28-03-2018 CIG75_RS05610 90bd932859de3eb17e00a9b67e1083c3 887 TIGRFAM TIGR00593 pola: DNA polymerase I 7 887 0.0 T 28-03-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CIG75_RS05610 90bd932859de3eb17e00a9b67e1083c3 887 Gene3D G3DSA:3.30.70.370 713 887 3.2E-54 T 28-03-2018 CIG75_RS05610 90bd932859de3eb17e00a9b67e1083c3 887 Gene3D G3DSA:3.30.70.370 615 706 5.4E-19 T 28-03-2018 CIG75_RS05610 90bd932859de3eb17e00a9b67e1083c3 887 Pfam PF00476 DNA polymerase family A 508 885 2.2E-162 T 28-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CIG75_RS10465 1658889cf01a275fe35b37f9434bad86 2181 SUPERFAMILY SSF52777 231 471 4.11E-65 T 28-03-2018 CIG75_RS10465 1658889cf01a275fe35b37f9434bad86 2181 SUPERFAMILY SSF47336 1012 1081 1.7E-19 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10465 1658889cf01a275fe35b37f9434bad86 2181 SUPERFAMILY SSF56801 466 1031 4.06E-160 T 28-03-2018 CIG75_RS10465 1658889cf01a275fe35b37f9434bad86 2181 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 529 932 9.0E-127 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS10465 1658889cf01a275fe35b37f9434bad86 2181 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1601 2001 3.2E-140 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS10465 1658889cf01a275fe35b37f9434bad86 2181 Gene3D G3DSA:3.40.50.980 1571 1729 2.2E-55 T 28-03-2018 CIG75_RS10465 1658889cf01a275fe35b37f9434bad86 2181 Gene3D G3DSA:3.40.50.980 499 656 9.7E-50 T 28-03-2018 CIG75_RS10465 1658889cf01a275fe35b37f9434bad86 2181 SUPERFAMILY SSF56801 1537 2097 7.85E-176 T 28-03-2018 CIG75_RS10465 1658889cf01a275fe35b37f9434bad86 2181 Gene3D G3DSA:3.30.559.10 1087 1309 6.4E-42 T 28-03-2018 CIG75_RS10465 1658889cf01a275fe35b37f9434bad86 2181 Gene3D G3DSA:3.30.559.10 7 248 6.1E-48 T 28-03-2018 CIG75_RS10465 1658889cf01a275fe35b37f9434bad86 2181 SUPERFAMILY SSF52777 50 223 7.67E-52 T 28-03-2018 CIG75_RS10465 1658889cf01a275fe35b37f9434bad86 2181 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1724 1735 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS10465 1658889cf01a275fe35b37f9434bad86 2181 SUPERFAMILY SSF47336 2078 2152 1.44E-18 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10465 1658889cf01a275fe35b37f9434bad86 2181 Gene3D G3DSA:3.40.50.980 1730 1889 5.3E-43 T 28-03-2018 CIG75_RS10465 1658889cf01a275fe35b37f9434bad86 2181 Gene3D G3DSA:3.40.50.980 657 818 1.3E-36 T 28-03-2018 CIG75_RS10465 1658889cf01a275fe35b37f9434bad86 2181 Gene3D G3DSA:1.10.1200.10 2092 2158 1.9E-20 T 28-03-2018 CIG75_RS10465 1658889cf01a275fe35b37f9434bad86 2181 SUPERFAMILY SSF52777 1110 1287 4.11E-47 T 28-03-2018 CIG75_RS10465 1658889cf01a275fe35b37f9434bad86 2181 SUPERFAMILY SSF52777 1295 1566 7.45E-66 T 28-03-2018 CIG75_RS10465 1658889cf01a275fe35b37f9434bad86 2181 Gene3D G3DSA:2.30.38.10 819 898 1.5E-23 T 28-03-2018 CIG75_RS10465 1658889cf01a275fe35b37f9434bad86 2181 Gene3D G3DSA:2.30.38.10 1890 1966 2.6E-23 T 28-03-2018 CIG75_RS10465 1658889cf01a275fe35b37f9434bad86 2181 Gene3D G3DSA:1.10.1200.10 1023 1086 2.3E-22 T 28-03-2018 CIG75_RS10465 1658889cf01a275fe35b37f9434bad86 2181 SMART SM00823 Phosphopantetheine attachment site 2085 2155 0.0095 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS10465 1658889cf01a275fe35b37f9434bad86 2181 SMART SM00823 Phosphopantetheine attachment site 1019 1088 5.3E-4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS10465 1658889cf01a275fe35b37f9434bad86 2181 Pfam PF00550 Phosphopantetheine attachment site 1021 1081 3.2E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10465 1658889cf01a275fe35b37f9434bad86 2181 Pfam PF00550 Phosphopantetheine attachment site 2087 2151 2.3E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10465 1658889cf01a275fe35b37f9434bad86 2181 Pfam PF13193 AMP-binding enzyme C-terminal domain 1985 2059 2.4E-10 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS10465 1658889cf01a275fe35b37f9434bad86 2181 Pfam PF13193 AMP-binding enzyme C-terminal domain 916 991 5.4E-11 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS10465 1658889cf01a275fe35b37f9434bad86 2181 ProSitePatterns PS00455 Putative AMP-binding domain signature. 650 661 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS10465 1658889cf01a275fe35b37f9434bad86 2181 Pfam PF00501 AMP-binding enzyme 1580 1977 9.7E-114 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS10465 1658889cf01a275fe35b37f9434bad86 2181 Pfam PF00501 AMP-binding enzyme 508 908 7.8E-98 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS10465 1658889cf01a275fe35b37f9434bad86 2181 Pfam PF00668 Condensation domain 1106 1558 5.9E-116 T 28-03-2018 IPR001242 Condensation domain CIG75_RS10465 1658889cf01a275fe35b37f9434bad86 2181 Pfam PF00668 Condensation domain 47 483 1.3E-117 T 28-03-2018 IPR001242 Condensation domain CIG75_RS10465 1658889cf01a275fe35b37f9434bad86 2181 Gene3D G3DSA:3.30.300.30 1972 2091 4.4E-41 T 28-03-2018 CIG75_RS10465 1658889cf01a275fe35b37f9434bad86 2181 Gene3D G3DSA:3.30.300.30 903 1022 8.2E-39 T 28-03-2018 CIG75_RS10465 1658889cf01a275fe35b37f9434bad86 2181 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1043 1058 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS04300 2e52bac9af4cbad50b0d0b0771276f38 319 Pfam PF00248 Aldo/keto reductase family 15 316 6.4E-81 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CIG75_RS04300 2e52bac9af4cbad50b0d0b0771276f38 319 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 272 285 1.8E-6 T 28-03-2018 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 CIG75_RS04300 2e52bac9af4cbad50b0d0b0771276f38 319 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 204 210 1.8E-6 T 28-03-2018 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 CIG75_RS04300 2e52bac9af4cbad50b0d0b0771276f38 319 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 109 119 1.8E-6 T 28-03-2018 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 CIG75_RS04300 2e52bac9af4cbad50b0d0b0771276f38 319 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 259 271 1.8E-6 T 28-03-2018 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 CIG75_RS04300 2e52bac9af4cbad50b0d0b0771276f38 319 Gene3D G3DSA:3.20.20.100 3 319 1.5E-102 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CIG75_RS04300 2e52bac9af4cbad50b0d0b0771276f38 319 SUPERFAMILY SSF51430 1 316 1.96E-103 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CIG75_RS14885 d8206d8f7b409074c0d51f23f09db76d 88 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 84 17.696 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS14885 d8206d8f7b409074c0d51f23f09db76d 88 Pfam PF01649 Ribosomal protein S20 2 83 1.2E-26 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS14885 d8206d8f7b409074c0d51f23f09db76d 88 SUPERFAMILY SSF46992 3 85 7.59E-25 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS14885 d8206d8f7b409074c0d51f23f09db76d 88 Gene3D G3DSA:1.20.58.110 1 88 2.2E-27 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS14885 d8206d8f7b409074c0d51f23f09db76d 88 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 17 83 6.0E-17 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS14885 d8206d8f7b409074c0d51f23f09db76d 88 TIGRFAM TIGR00029 S20: ribosomal protein bS20 1 85 1.7E-25 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS04430 33c8fc8124a9c415192f5628521744fc 233 Pfam PF00005 ABC transporter 21 169 6.3E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS04430 33c8fc8124a9c415192f5628521744fc 233 SMART SM00382 30 225 5.7E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS04430 33c8fc8124a9c415192f5628521744fc 233 SUPERFAMILY SSF52540 1 227 3.0E-72 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS04430 33c8fc8124a9c415192f5628521744fc 233 Gene3D G3DSA:3.40.50.300 1 228 1.4E-64 T 28-03-2018 CIG75_RS15095 f9ae94060507d20c17df66222c12f10a 395 PIRSF PIRSF001434 1 395 1.4E-155 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CIG75_RS15095 f9ae94060507d20c17df66222c12f10a 395 Gene3D G3DSA:3.90.1150.10 264 395 5.9E-58 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CIG75_RS15095 f9ae94060507d20c17df66222c12f10a 395 Gene3D G3DSA:3.40.640.10 9 262 6.4E-58 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CIG75_RS15095 f9ae94060507d20c17df66222c12f10a 395 SUPERFAMILY SSF53383 25 394 6.6E-123 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CIG75_RS15095 f9ae94060507d20c17df66222c12f10a 395 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 13 393 1.3E-155 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CIG75_RS08100 54e1a1e4c82e15d6aabe790bcc536533 293 Pfam PF01551 Peptidase family M23 192 279 4.1E-12 T 28-03-2018 IPR016047 Peptidase M23 CIG75_RS08100 54e1a1e4c82e15d6aabe790bcc536533 293 SUPERFAMILY SSF51261 130 285 4.39E-10 T 28-03-2018 IPR011055 Duplicated hybrid motif CIG75_RS08100 54e1a1e4c82e15d6aabe790bcc536533 293 Gene3D G3DSA:2.70.70.10 51 289 5.2E-14 T 28-03-2018 CIG75_RS20480 17566e8cfea8c4e03c35c8bdb43ea750 602 SUPERFAMILY SSF55785 465 529 9.16E-5 T 28-03-2018 IPR000014 PAS domain CIG75_RS20480 17566e8cfea8c4e03c35c8bdb43ea750 602 Gene3D G3DSA:3.30.450.40 277 466 2.9E-12 T 28-03-2018 IPR029016 GAF domain-like CIG75_RS20480 17566e8cfea8c4e03c35c8bdb43ea750 602 SUPERFAMILY SSF55781 314 478 6.13E-10 T 28-03-2018 IPR029016 GAF domain-like CIG75_RS20480 17566e8cfea8c4e03c35c8bdb43ea750 602 Gene3D G3DSA:3.30.450.20 467 592 3.2E-7 T 28-03-2018 CIG75_RS20480 17566e8cfea8c4e03c35c8bdb43ea750 602 SMART SM00065 331 471 0.003 T 28-03-2018 IPR003018 GAF domain GO:0005515 CIG75_RS20480 17566e8cfea8c4e03c35c8bdb43ea750 602 Gene3D G3DSA:1.20.120.30 46 178 2.8E-4 T 28-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain CIG75_RS09400 7077f61486e12fecc29a732398479f1a 442 Gene3D G3DSA:3.30.300.20 351 435 4.8E-33 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CIG75_RS09400 7077f61486e12fecc29a732398479f1a 442 Gene3D G3DSA:1.20.120.430 2 70 4.1E-19 T 28-03-2018 CIG75_RS09400 7077f61486e12fecc29a732398479f1a 442 Gene3D G3DSA:3.40.50.300 231 350 5.2E-15 T 28-03-2018 CIG75_RS09400 7077f61486e12fecc29a732398479f1a 442 PIRSF PIRSF006485 2 442 2.1E-177 T 28-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 CIG75_RS09400 7077f61486e12fecc29a732398479f1a 442 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 354 434 3.0E-32 T 28-03-2018 IPR032859 GTPase Der, C-terminal KH-domain-like CIG75_RS09400 7077f61486e12fecc29a732398479f1a 442 Gene3D G3DSA:1.20.120.430 71 230 4.9E-44 T 28-03-2018 CIG75_RS09400 7077f61486e12fecc29a732398479f1a 442 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 179 199 9.7E-5 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CIG75_RS09400 7077f61486e12fecc29a732398479f1a 442 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 249 267 9.7E-5 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CIG75_RS09400 7077f61486e12fecc29a732398479f1a 442 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 4 433 3.2E-176 T 28-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 CIG75_RS09400 7077f61486e12fecc29a732398479f1a 442 SUPERFAMILY SSF52540 5 169 8.13E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS09400 7077f61486e12fecc29a732398479f1a 442 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 3 156 2.5E-25 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CIG75_RS09400 7077f61486e12fecc29a732398479f1a 442 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 177 345 5.9E-24 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CIG75_RS09400 7077f61486e12fecc29a732398479f1a 442 SUPERFAMILY SSF52540 139 438 2.98E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS09400 7077f61486e12fecc29a732398479f1a 442 Pfam PF01926 50S ribosome-binding GTPase 179 296 3.2E-24 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CIG75_RS09400 7077f61486e12fecc29a732398479f1a 442 Pfam PF01926 50S ribosome-binding GTPase 6 121 1.7E-27 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CIG75_RS09400 7077f61486e12fecc29a732398479f1a 442 Hamap MF_00195 GTPase Der [der]. 3 437 40.891 T 28-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 CIG75_RS03555 38d8b650ee660c7333c2bb00400c2e63 160 Gene3D G3DSA:1.20.5.170 3 59 7.6E-10 T 28-03-2018 CIG75_RS03555 38d8b650ee660c7333c2bb00400c2e63 160 Gene3D G3DSA:1.20.5.170 60 103 4.3E-9 T 28-03-2018 CIG75_RS03555 38d8b650ee660c7333c2bb00400c2e63 160 SUPERFAMILY SSF58113 30 98 3.27E-5 T 28-03-2018 CIG75_RS11290 015db1454f40820d3f9870e183fde88d 339 Pfam PF13531 Bacterial extracellular solute-binding protein 37 289 1.9E-38 T 28-03-2018 CIG75_RS11290 015db1454f40820d3f9870e183fde88d 339 Gene3D G3DSA:3.40.190.10 29 132 1.7E-16 T 28-03-2018 CIG75_RS11290 015db1454f40820d3f9870e183fde88d 339 Gene3D G3DSA:3.40.190.10 133 338 1.5E-35 T 28-03-2018 CIG75_RS11290 015db1454f40820d3f9870e183fde88d 339 SUPERFAMILY SSF53850 32 335 4.56E-60 T 28-03-2018 CIG75_RS11290 015db1454f40820d3f9870e183fde88d 339 TIGRFAM TIGR00971 3a0106s03: sulfate ABC transporter, sulfate-binding protein 33 335 1.1E-68 T 28-03-2018 IPR005669 Thiosulphate/Sulfate-binding protein GO:0008272|GO:0015419 CIG75_RS06690 5d2d5109459e29c06629e1f9785168cc 824 Gene3D G3DSA:1.10.439.10 37 200 1.7E-54 T 28-03-2018 IPR023343 Penicillin amidase type, domain1 GO:0016811 CIG75_RS06690 5d2d5109459e29c06629e1f9785168cc 824 Pfam PF01804 Penicillin amidase 46 812 1.2E-220 T 28-03-2018 IPR002692 Penicillin/GL-7-ACA/AHL/aculeacin-A acylase GO:0016787|GO:0017000 CIG75_RS06690 5d2d5109459e29c06629e1f9785168cc 824 PIRSF PIRSF001227 5 824 4.0E-204 T 28-03-2018 IPR014395 Penicillin/GL-7-ACA/AHL acylase GO:0016811 CIG75_RS06690 5d2d5109459e29c06629e1f9785168cc 824 Gene3D G3DSA:3.60.20.10 266 637 5.8E-108 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CIG75_RS06690 5d2d5109459e29c06629e1f9785168cc 824 Gene3D G3DSA:3.60.20.10 668 815 2.5E-21 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CIG75_RS06690 5d2d5109459e29c06629e1f9785168cc 824 SUPERFAMILY SSF56235 44 823 7.46E-224 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CIG75_RS18865 ba4f4f9bb42554a007e16418de7b0cd8 344 SUPERFAMILY SSF55347 148 312 3.2E-56 T 28-03-2018 CIG75_RS18865 ba4f4f9bb42554a007e16418de7b0cd8 344 Gene3D G3DSA:3.40.50.720 1 157 1.0E-42 T 28-03-2018 CIG75_RS18865 ba4f4f9bb42554a007e16418de7b0cd8 344 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 157 315 7.5E-28 T 28-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CIG75_RS18865 ba4f4f9bb42554a007e16418de7b0cd8 344 SUPERFAMILY SSF51735 2 176 6.44E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS18865 ba4f4f9bb42554a007e16418de7b0cd8 344 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 1 343 4.9E-133 T 28-03-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CIG75_RS18865 ba4f4f9bb42554a007e16418de7b0cd8 344 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 1 338 43.309 T 28-03-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CIG75_RS18865 ba4f4f9bb42554a007e16418de7b0cd8 344 Gene3D G3DSA:3.30.360.10 158 312 4.4E-62 T 28-03-2018 CIG75_RS18865 ba4f4f9bb42554a007e16418de7b0cd8 344 SMART SM00859 2 140 8.9E-45 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CIG75_RS18865 ba4f4f9bb42554a007e16418de7b0cd8 344 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 143 159 - T 28-03-2018 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CIG75_RS18865 ba4f4f9bb42554a007e16418de7b0cd8 344 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 2 139 4.1E-30 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CIG75_RS08545 53c3e88f918191c14c5e80d600c79ab2 216 TIGRFAM TIGR02831 spo_II_M: stage II sporulation protein M 13 211 3.1E-54 T 28-03-2018 IPR014196 Stage II sporulation protein M CIG75_RS08545 53c3e88f918191c14c5e80d600c79ab2 216 PIRSF PIRSF038973 5 216 1.5E-55 T 28-03-2018 IPR014196 Stage II sporulation protein M CIG75_RS08545 53c3e88f918191c14c5e80d600c79ab2 216 Pfam PF01944 Stage II sporulation protein M 25 206 2.2E-26 T 28-03-2018 IPR002798 Stage II sporulation protein M-like CIG75_RS13605 0c6c690d64a26e491ab28effafe61590 256 SUPERFAMILY SSF51735 15 254 8.11E-83 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS13605 0c6c690d64a26e491ab28effafe61590 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 91 102 1.7E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS13605 0c6c690d64a26e491ab28effafe61590 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 152 1.7E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS13605 0c6c690d64a26e491ab28effafe61590 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 164 183 1.7E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS13605 0c6c690d64a26e491ab28effafe61590 256 Gene3D G3DSA:3.40.50.720 8 47 2.8E-8 T 28-03-2018 CIG75_RS13605 0c6c690d64a26e491ab28effafe61590 256 Gene3D G3DSA:3.40.50.720 48 256 3.4E-65 T 28-03-2018 CIG75_RS13605 0c6c690d64a26e491ab28effafe61590 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 218 238 6.0E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS13605 0c6c690d64a26e491ab28effafe61590 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 183 6.0E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS13605 0c6c690d64a26e491ab28effafe61590 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 138 154 6.0E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS13605 0c6c690d64a26e491ab28effafe61590 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 91 102 6.0E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS13605 0c6c690d64a26e491ab28effafe61590 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 202 6.0E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS13605 0c6c690d64a26e491ab28effafe61590 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 6.0E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS13605 0c6c690d64a26e491ab28effafe61590 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 21 254 8.4E-62 T 28-03-2018 CIG75_RS13605 0c6c690d64a26e491ab28effafe61590 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 151 179 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CIG75_RS12360 4cb8799987f983cbdce3535199778278 246 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 7 245 2.1E-107 T 28-03-2018 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CIG75_RS12360 4cb8799987f983cbdce3535199778278 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 4.4E-51 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS12360 4cb8799987f983cbdce3535199778278 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 4.4E-51 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS12360 4cb8799987f983cbdce3535199778278 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 4.4E-51 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS12360 4cb8799987f983cbdce3535199778278 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 4.4E-51 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS12360 4cb8799987f983cbdce3535199778278 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 4.4E-51 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS12360 4cb8799987f983cbdce3535199778278 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 4.4E-51 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS12360 4cb8799987f983cbdce3535199778278 246 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 244 3.4E-74 T 28-03-2018 CIG75_RS12360 4cb8799987f983cbdce3535199778278 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 3.4E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS12360 4cb8799987f983cbdce3535199778278 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 3.4E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS12360 4cb8799987f983cbdce3535199778278 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 3.4E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS12360 4cb8799987f983cbdce3535199778278 246 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 185 1.3E-6 T 28-03-2018 CIG75_RS12360 4cb8799987f983cbdce3535199778278 246 Gene3D G3DSA:3.40.50.720 1 38 4.8E-10 T 28-03-2018 CIG75_RS12360 4cb8799987f983cbdce3535199778278 246 Gene3D G3DSA:3.40.50.720 39 246 4.8E-73 T 28-03-2018 CIG75_RS12360 4cb8799987f983cbdce3535199778278 246 SUPERFAMILY SSF51735 4 246 2.8E-97 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS18395 89cd144c22626a454fca3a66131a78a6 340 PIRSF PIRSF011570 1 335 5.9E-161 T 28-03-2018 IPR010894 Stage V sporulation AD CIG75_RS18395 89cd144c22626a454fca3a66131a78a6 340 Pfam PF07451 Stage V sporulation protein AD (SpoVAD) 4 332 2.1E-156 T 28-03-2018 IPR010894 Stage V sporulation AD CIG75_RS18395 89cd144c22626a454fca3a66131a78a6 340 Gene3D G3DSA:3.40.47.10 46 185 2.5E-12 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS18395 89cd144c22626a454fca3a66131a78a6 340 SUPERFAMILY SSF53901 56 283 2.98E-19 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS18395 89cd144c22626a454fca3a66131a78a6 340 TIGRFAM TIGR02845 spore_V_AD: stage V sporulation protein AD 5 332 1.0E-153 T 28-03-2018 IPR010894 Stage V sporulation AD CIG75_RS12490 a5971cc37e022d800523a634ac4c5927 250 SUPERFAMILY SSF81606 1 241 1.96E-65 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CIG75_RS12490 a5971cc37e022d800523a634ac4c5927 250 SMART SM00331 7 242 1.4E-39 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CIG75_RS12490 a5971cc37e022d800523a634ac4c5927 250 Pfam PF13672 Protein phosphatase 2C 14 211 6.5E-19 T 28-03-2018 CIG75_RS12490 a5971cc37e022d800523a634ac4c5927 250 SMART SM00332 1 240 2.2E-24 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CIG75_RS12490 a5971cc37e022d800523a634ac4c5927 250 Gene3D G3DSA:3.60.40.10 1 242 1.3E-46 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CIG75_RS15415 9abb114a6bfac4757962464d62e266b7 484 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 402 459 6.5E-14 T 28-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 CIG75_RS15415 9abb114a6bfac4757962464d62e266b7 484 SUPERFAMILY SSF55904 341 484 3.92E-37 T 28-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 CIG75_RS15415 9abb114a6bfac4757962464d62e266b7 484 SUPERFAMILY SSF53383 5 383 5.38E-91 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CIG75_RS15415 9abb114a6bfac4757962464d62e266b7 484 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 5 370 3.2E-102 T 28-03-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 CIG75_RS15415 9abb114a6bfac4757962464d62e266b7 484 Gene3D G3DSA:3.90.1150.10 309 401 1.1E-26 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CIG75_RS15415 9abb114a6bfac4757962464d62e266b7 484 Gene3D G3DSA:3.90.100.10 402 484 3.4E-29 T 28-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 CIG75_RS15415 9abb114a6bfac4757962464d62e266b7 484 Gene3D G3DSA:3.40.640.10 5 283 1.3E-47 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CIG75_RS15415 9abb114a6bfac4757962464d62e266b7 484 ProSitePatterns PS00703 Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site. 220 234 - T 28-03-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 CIG75_RS04120 3464ad61b0ef5b7d5e803a2d116018a1 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 3.5E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CIG75_RS04120 3464ad61b0ef5b7d5e803a2d116018a1 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 3.5E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CIG75_RS04120 3464ad61b0ef5b7d5e803a2d116018a1 197 SUPERFAMILY SSF48498 89 190 8.9E-15 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CIG75_RS04120 3464ad61b0ef5b7d5e803a2d116018a1 197 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 86 195 6.1E-11 T 28-03-2018 CIG75_RS04120 3464ad61b0ef5b7d5e803a2d116018a1 197 SUPERFAMILY SSF46689 3 77 4.0E-19 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CIG75_RS04120 3464ad61b0ef5b7d5e803a2d116018a1 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 60 9.9E-16 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CIG75_RS04120 3464ad61b0ef5b7d5e803a2d116018a1 197 Gene3D G3DSA:1.10.357.10 64 197 5.6E-18 T 28-03-2018 CIG75_RS04120 3464ad61b0ef5b7d5e803a2d116018a1 197 Gene3D G3DSA:1.10.10.60 2 63 6.1E-17 T 28-03-2018 CIG75_RS14040 05f157fffd62c3d27df31d1f9d993f7c 397 Hamap MF_00021 tRNA sulfurtransferase [thiI]. 1 397 152.808 T 28-03-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 CIG75_RS14040 05f157fffd62c3d27df31d1f9d993f7c 397 SUPERFAMILY SSF52402 178 385 1.95E-55 T 28-03-2018 CIG75_RS14040 05f157fffd62c3d27df31d1f9d993f7c 397 TIGRFAM TIGR00342 TIGR00342: tRNA sulfurtransferase ThiI 10 380 2.6E-120 T 28-03-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 CIG75_RS14040 05f157fffd62c3d27df31d1f9d993f7c 397 Pfam PF02926 THUMP domain 47 167 3.7E-21 T 28-03-2018 IPR004114 THUMP domain GO:0003723 CIG75_RS14040 05f157fffd62c3d27df31d1f9d993f7c 397 Gene3D G3DSA:3.40.50.620 179 395 4.7E-37 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CIG75_RS14040 05f157fffd62c3d27df31d1f9d993f7c 397 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 179 374 3.9E-72 T 28-03-2018 IPR020536 Thil, AANH domain GO:0004810 CIG75_RS14040 05f157fffd62c3d27df31d1f9d993f7c 397 Gene3D G3DSA:3.30.2300.10 85 167 1.1E-18 T 28-03-2018 CIG75_RS14040 05f157fffd62c3d27df31d1f9d993f7c 397 SUPERFAMILY SSF143437 5 177 1.92E-42 T 28-03-2018 CIG75_RS14040 05f157fffd62c3d27df31d1f9d993f7c 397 Gene3D G3DSA:3.30.70.1510 4 80 8.7E-20 T 28-03-2018 CIG75_RS14040 05f157fffd62c3d27df31d1f9d993f7c 397 SMART SM00981 73 169 1.2E-17 T 28-03-2018 IPR004114 THUMP domain GO:0003723 CIG75_RS01160 e11411ed5c384dff94973a82581f34cb 222 Pfam PF07299 Elongation factor G-binding protein, N-terminal 10 92 6.9E-15 T 28-03-2018 IPR010841 Elongation factor G-binding protein, N-terminal CIG75_RS01160 e11411ed5c384dff94973a82581f34cb 222 Pfam PF16571 FBP C-terminal treble-clef zinc-finger 106 211 2.6E-14 T 28-03-2018 IPR032330 Elongation factor G-binding protein, C-terminal treble-clef zinc-finger CIG75_RS14875 b24ada2c2be9b1e27d17a173d860039d 150 Pfam PF16167 Domain of unknown function (DUF4871) 32 147 1.6E-8 T 28-03-2018 IPR032366 Protein of unknown function DUF4871 CIG75_RS04665 096f15520465564d1bacd89ed33572a0 95 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 94 1.1E-26 T 28-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS04665 096f15520465564d1bacd89ed33572a0 95 Pfam PF01250 Ribosomal protein S6 4 91 1.9E-29 T 28-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS04665 096f15520465564d1bacd89ed33572a0 95 SUPERFAMILY SSF54995 1 94 1.57E-32 T 28-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS04665 096f15520465564d1bacd89ed33572a0 95 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 95 21.56 T 28-03-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 CIG75_RS04665 096f15520465564d1bacd89ed33572a0 95 Gene3D G3DSA:3.30.70.60 1 95 3.2E-30 T 28-03-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 CIG75_RS08490 b22c6737d9096ef085f0499447a797a0 74 ProDom PD058324 UPF0349 LMO2392 BLI03401/BL03152 SA0800 SAR0901 LIN2491 SERP0525 GK2958 BT9727_4649 BC4937 2 69 9.0E-4 T 28-03-2018 CIG75_RS08490 b22c6737d9096ef085f0499447a797a0 74 Pfam PF07293 Protein of unknown function (DUF1450) 2 69 2.8E-12 T 28-03-2018 IPR009910 Protein of unknown function DUF1450 CIG75_RS11560 e013000f6bc6d97f40ba909c304d6de1 271 PIRSF PIRSF004789 1 262 3.1E-89 T 28-03-2018 IPR005235 Metallophosphoesterase, YmdB-like CIG75_RS11560 e013000f6bc6d97f40ba909c304d6de1 271 TIGRFAM TIGR00282 TIGR00282: metallophosphoesterase, MG_246/BB_0505 family 1 259 3.6E-87 T 28-03-2018 IPR005235 Metallophosphoesterase, YmdB-like CIG75_RS11560 e013000f6bc6d97f40ba909c304d6de1 271 Gene3D G3DSA:3.60.21.10 1 271 6.5E-41 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CIG75_RS11560 e013000f6bc6d97f40ba909c304d6de1 271 SUPERFAMILY SSF56300 1 255 7.97E-78 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CIG75_RS11560 e013000f6bc6d97f40ba909c304d6de1 271 Pfam PF13277 YmdB-like protein 4 254 2.8E-99 T 28-03-2018 IPR005235 Metallophosphoesterase, YmdB-like CIG75_RS16730 78ed19d10e24b18cb6b797129ed255c0 596 Pfam PF00351 Biopterin-dependent aromatic amino acid hydroxylase 41 173 3.2E-11 T 28-03-2018 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 CIG75_RS16730 78ed19d10e24b18cb6b797129ed255c0 596 Pfam PF00351 Biopterin-dependent aromatic amino acid hydroxylase 220 307 4.3E-15 T 28-03-2018 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 CIG75_RS16730 78ed19d10e24b18cb6b797129ed255c0 596 SUPERFAMILY SSF56534 216 330 5.49E-74 T 28-03-2018 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 CIG75_RS16730 78ed19d10e24b18cb6b797129ed255c0 596 SUPERFAMILY SSF56534 25 170 5.49E-74 T 28-03-2018 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 CIG75_RS16730 78ed19d10e24b18cb6b797129ed255c0 596 Gene3D G3DSA:1.10.800.10 23 331 1.2E-72 T 28-03-2018 IPR001273 Aromatic amino acid hydroxylase GO:0004497|GO:0005506|GO:0009072|GO:0055114 CIG75_RS20375 721f629b54eb53263d8f5f2526e6e10e 199 SMART SM00382 7 195 1.4E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS20375 721f629b54eb53263d8f5f2526e6e10e 199 Gene3D G3DSA:3.40.50.300 1 199 1.0E-64 T 28-03-2018 CIG75_RS20375 721f629b54eb53263d8f5f2526e6e10e 199 ProSitePatterns PS00211 ABC transporters family signature. 120 134 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS20375 721f629b54eb53263d8f5f2526e6e10e 199 SUPERFAMILY SSF52540 1 198 1.0E-67 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS20375 721f629b54eb53263d8f5f2526e6e10e 199 Pfam PF00005 ABC transporter 1 147 2.9E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS03065 9845e9e17e002aa30cec8035f98866d2 753 Gene3D G3DSA:3.40.50.300 583 753 2.2E-20 T 28-03-2018 CIG75_RS03065 9845e9e17e002aa30cec8035f98866d2 753 SUPERFAMILY SSF52540 493 743 1.88E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS03065 9845e9e17e002aa30cec8035f98866d2 753 SUPERFAMILY SSF52540 191 269 1.88E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS03065 9845e9e17e002aa30cec8035f98866d2 753 Gene3D G3DSA:3.40.50.300 196 571 6.1E-29 T 28-03-2018 CIG75_RS03065 9845e9e17e002aa30cec8035f98866d2 753 Pfam PF13245 AAA domain 202 558 4.2E-9 T 28-03-2018 CIG75_RS06025 c910a765666d63836e9adb393385ad9a 141 SUPERFAMILY SSF102829 56 130 1.96E-16 T 28-03-2018 IPR007838 Cell division protein ZapA-like CIG75_RS06025 c910a765666d63836e9adb393385ad9a 141 Pfam PF05164 Cell division protein ZapA 59 123 2.4E-15 T 28-03-2018 IPR007838 Cell division protein ZapA-like CIG75_RS16220 f76927156ccee2584f72d9ead12d736e 1218 Gene3D G3DSA:2.60.40.10 627 722 9.3E-6 T 28-03-2018 IPR013783 Immunoglobulin-like fold CIG75_RS16220 f76927156ccee2584f72d9ead12d736e 1218 Gene3D G3DSA:2.60.40.10 129 213 3.3E-8 T 28-03-2018 IPR013783 Immunoglobulin-like fold CIG75_RS16220 f76927156ccee2584f72d9ead12d736e 1218 SMART SM00060 529 611 0.1 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CIG75_RS16220 f76927156ccee2584f72d9ead12d736e 1218 SMART SM00060 129 209 0.058 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CIG75_RS16220 f76927156ccee2584f72d9ead12d736e 1218 SMART SM00060 425 505 110.0 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CIG75_RS16220 f76927156ccee2584f72d9ead12d736e 1218 SMART SM00060 633 712 2.3 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CIG75_RS16220 f76927156ccee2584f72d9ead12d736e 1218 SMART SM00060 827 909 1.5 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CIG75_RS16220 f76927156ccee2584f72d9ead12d736e 1218 SMART SM00060 230 322 28.0 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CIG75_RS16220 f76927156ccee2584f72d9ead12d736e 1218 SMART SM00060 730 814 0.36 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CIG75_RS16220 f76927156ccee2584f72d9ead12d736e 1218 SMART SM00060 328 410 1.9E-7 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CIG75_RS16220 f76927156ccee2584f72d9ead12d736e 1218 Gene3D G3DSA:2.60.40.10 827 916 2.6E-6 T 28-03-2018 IPR013783 Immunoglobulin-like fold CIG75_RS16220 f76927156ccee2584f72d9ead12d736e 1218 Gene3D G3DSA:2.60.40.10 527 615 1.2E-5 T 28-03-2018 IPR013783 Immunoglobulin-like fold CIG75_RS16220 f76927156ccee2584f72d9ead12d736e 1218 Gene3D G3DSA:2.60.40.10 1023 1103 1.5E-5 T 28-03-2018 IPR013783 Immunoglobulin-like fold CIG75_RS16220 f76927156ccee2584f72d9ead12d736e 1218 SUPERFAMILY SSF49265 326 492 4.2E-13 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CIG75_RS16220 f76927156ccee2584f72d9ead12d736e 1218 Gene3D G3DSA:2.60.40.10 214 320 8.7E-4 T 28-03-2018 IPR013783 Immunoglobulin-like fold CIG75_RS16220 f76927156ccee2584f72d9ead12d736e 1218 Gene3D G3DSA:2.60.40.10 418 509 0.0012 T 28-03-2018 IPR013783 Immunoglobulin-like fold CIG75_RS16220 f76927156ccee2584f72d9ead12d736e 1218 Gene3D G3DSA:2.60.40.10 738 816 1.4E-4 T 28-03-2018 IPR013783 Immunoglobulin-like fold CIG75_RS16220 f76927156ccee2584f72d9ead12d736e 1218 SUPERFAMILY SSF49265 132 208 1.67E-7 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CIG75_RS16220 f76927156ccee2584f72d9ead12d736e 1218 SUPERFAMILY SSF49265 842 912 3.97E-7 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CIG75_RS16220 f76927156ccee2584f72d9ead12d736e 1218 Pfam PF00041 Fibronectin type III domain 132 207 1.8E-8 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CIG75_RS16220 f76927156ccee2584f72d9ead12d736e 1218 Pfam PF00041 Fibronectin type III domain 330 407 2.1E-5 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CIG75_RS16220 f76927156ccee2584f72d9ead12d736e 1218 Pfam PF00041 Fibronectin type III domain 642 709 1.4E-5 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CIG75_RS16220 f76927156ccee2584f72d9ead12d736e 1218 SUPERFAMILY SSF81296 1040 1107 8.4E-6 T 28-03-2018 IPR014756 Immunoglobulin E-set CIG75_RS16220 f76927156ccee2584f72d9ead12d736e 1218 Gene3D G3DSA:2.60.40.10 321 417 6.9E-13 T 28-03-2018 IPR013783 Immunoglobulin-like fold CIG75_RS16220 f76927156ccee2584f72d9ead12d736e 1218 SUPERFAMILY SSF49265 533 710 2.65E-7 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CIG75_RS17785 f5382db7eb42452062fb62b7fa2bf2bb 422 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 79 93 - T 28-03-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CIG75_RS17785 f5382db7eb42452062fb62b7fa2bf2bb 422 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 3 422 44.993 T 28-03-2018 IPR034373 Adenosylhomocysteinase GO:0004013|GO:0019510|GO:0051287 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-2408508 CIG75_RS17785 f5382db7eb42452062fb62b7fa2bf2bb 422 SUPERFAMILY SSF51735 191 353 5.48E-68 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS17785 f5382db7eb42452062fb62b7fa2bf2bb 422 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 10 421 5.6E-179 T 28-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CIG75_RS17785 f5382db7eb42452062fb62b7fa2bf2bb 422 SMART SM00997 191 352 1.1E-106 T 28-03-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CIG75_RS17785 f5382db7eb42452062fb62b7fa2bf2bb 422 SUPERFAMILY SSF52283 353 421 1.98E-91 T 28-03-2018 CIG75_RS17785 f5382db7eb42452062fb62b7fa2bf2bb 422 SUPERFAMILY SSF52283 7 190 1.98E-91 T 28-03-2018 CIG75_RS17785 f5382db7eb42452062fb62b7fa2bf2bb 422 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 213 229 - T 28-03-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CIG75_RS17785 f5382db7eb42452062fb62b7fa2bf2bb 422 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 191 350 1.4E-55 T 28-03-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CIG75_RS17785 f5382db7eb42452062fb62b7fa2bf2bb 422 Gene3D G3DSA:3.40.50.1480 211 405 1.7E-62 T 28-03-2018 CIG75_RS17785 f5382db7eb42452062fb62b7fa2bf2bb 422 SMART SM00996 7 422 1.1E-125 T 28-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CIG75_RS17785 f5382db7eb42452062fb62b7fa2bf2bb 422 PIRSF PIRSF001109 2 422 1.4E-174 T 28-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CIG75_RS17785 f5382db7eb42452062fb62b7fa2bf2bb 422 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 9 139 8.0E-29 T 28-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CIG75_RS17785 f5382db7eb42452062fb62b7fa2bf2bb 422 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 145 418 1.3E-23 T 28-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CIG75_RS17785 f5382db7eb42452062fb62b7fa2bf2bb 422 Gene3D G3DSA:3.40.50.1480 1 141 2.4E-44 T 28-03-2018 CIG75_RS17785 f5382db7eb42452062fb62b7fa2bf2bb 422 Gene3D G3DSA:3.40.50.1480 142 210 3.8E-15 T 28-03-2018 CIG75_RS18575 22bc49cc199cd8e7176c318988058d89 699 SUPERFAMILY SSF82866 513 694 1.96E-25 T 28-03-2018 CIG75_RS18575 22bc49cc199cd8e7176c318988058d89 699 Gene3D G3DSA:1.20.1640.10 139 345 9.2E-31 T 28-03-2018 CIG75_RS18575 22bc49cc199cd8e7176c318988058d89 699 Gene3D G3DSA:1.20.1640.10 481 695 9.9E-28 T 28-03-2018 CIG75_RS18575 22bc49cc199cd8e7176c318988058d89 699 Pfam PF03176 MMPL family 454 692 4.3E-44 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CIG75_RS18575 22bc49cc199cd8e7176c318988058d89 699 Pfam PF03176 MMPL family 50 376 2.4E-60 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CIG75_RS18575 22bc49cc199cd8e7176c318988058d89 699 SUPERFAMILY SSF82866 123 348 7.98E-32 T 28-03-2018 CIG75_RS17425 276f54f726103dcb91d60e1887a0f6f8 287 SUPERFAMILY SSF81345 2 256 1.96E-36 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CIG75_RS17425 276f54f726103dcb91d60e1887a0f6f8 287 Pfam PF00950 ABC 3 transport family 3 256 1.7E-68 T 28-03-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 CIG75_RS17425 276f54f726103dcb91d60e1887a0f6f8 287 Gene3D G3DSA:1.10.3470.10 2 261 9.4E-27 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CIG75_RS16430 372e5804e9f75c12ae934db718a94f30 416 SUPERFAMILY SSF55681 5 316 6.32E-87 T 28-03-2018 CIG75_RS16430 372e5804e9f75c12ae934db718a94f30 416 PIRSF PIRSF001549 1 415 1.8E-107 T 28-03-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 CIG75_RS16430 372e5804e9f75c12ae934db718a94f30 416 Gene3D G3DSA:3.30.930.10 1 321 5.7E-66 T 28-03-2018 CIG75_RS16430 372e5804e9f75c12ae934db718a94f30 416 Gene3D G3DSA:3.40.50.800 323 416 2.7E-16 T 28-03-2018 IPR004154 Anticodon-binding CIG75_RS16430 372e5804e9f75c12ae934db718a94f30 416 Pfam PF13393 Histidyl-tRNA synthetase 9 307 7.6E-46 T 28-03-2018 CIG75_RS16430 372e5804e9f75c12ae934db718a94f30 416 SUPERFAMILY SSF52954 325 414 6.19E-21 T 28-03-2018 IPR004154 Anticodon-binding CIG75_RS16430 372e5804e9f75c12ae934db718a94f30 416 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 2 416 30.645 T 28-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 CIG75_RS16430 372e5804e9f75c12ae934db718a94f30 416 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 6 406 1.9E-139 T 28-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 CIG75_RS16430 372e5804e9f75c12ae934db718a94f30 416 Pfam PF03129 Anticodon binding domain 327 413 9.4E-11 T 28-03-2018 IPR004154 Anticodon-binding CIG75_RS16140 57264550575bf29dc58298e0e5b78a76 618 SUPERFAMILY SSF52540 55 268 5.44E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS16140 57264550575bf29dc58298e0e5b78a76 618 Pfam PF02361 Cobalt transport protein 380 588 9.6E-20 T 28-03-2018 IPR003339 ABC/ECF transporter, transmembrane component CIG75_RS16140 57264550575bf29dc58298e0e5b78a76 618 Pfam PF00005 ABC transporter 56 205 2.9E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS16140 57264550575bf29dc58298e0e5b78a76 618 ProSitePatterns PS00211 ABC transporters family signature. 177 191 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS16140 57264550575bf29dc58298e0e5b78a76 618 SMART SM00382 65 254 5.0E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS16140 57264550575bf29dc58298e0e5b78a76 618 Gene3D G3DSA:3.40.50.300 49 373 1.6E-56 T 28-03-2018 CIG75_RS01880 ff81992421d3b0da6f703134995302d2 188 PIRSF PIRSF007510 5 184 1.6E-72 T 28-03-2018 IPR006340 Protein of unknown function DUF436 CIG75_RS01880 ff81992421d3b0da6f703134995302d2 188 Gene3D G3DSA:3.40.50.10360 8 184 4.8E-76 T 28-03-2018 IPR006340 Protein of unknown function DUF436 CIG75_RS01880 ff81992421d3b0da6f703134995302d2 188 Hamap MF_00800 UPF0340 protein . 1 188 81.575 T 28-03-2018 IPR006340 Protein of unknown function DUF436 CIG75_RS01880 ff81992421d3b0da6f703134995302d2 188 ProDom PD102102 UPF0340 3D-STRUCTURE YWLG SMU.87 STU1894 BT9727_4999 TRANSFERASE TTE0860 SPY1898/M5005_SPY1614 TT1679 19 182 2.0E-44 T 28-03-2018 IPR006340 Protein of unknown function DUF436 CIG75_RS01880 ff81992421d3b0da6f703134995302d2 188 TIGRFAM TIGR01440 TIGR01440: TIGR01440 family protein 13 182 3.3E-69 T 28-03-2018 IPR006340 Protein of unknown function DUF436 CIG75_RS01880 ff81992421d3b0da6f703134995302d2 188 Pfam PF04260 Protein of unknown function (DUF436) 13 182 3.0E-74 T 28-03-2018 IPR006340 Protein of unknown function DUF436 CIG75_RS01880 ff81992421d3b0da6f703134995302d2 188 SUPERFAMILY SSF110710 9 183 2.46E-70 T 28-03-2018 CIG75_RS13330 fd75eac6b7e5e0a0f72a932255b7bb78 163 Gene3D G3DSA:3.90.79.10 2 161 8.6E-20 T 28-03-2018 CIG75_RS13330 fd75eac6b7e5e0a0f72a932255b7bb78 163 Pfam PF00293 NUDIX domain 13 129 2.1E-14 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CIG75_RS13330 fd75eac6b7e5e0a0f72a932255b7bb78 163 SUPERFAMILY SSF55811 13 140 1.02E-21 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CIG75_RS07630 ad3eb53a2857f9faae8ca2484d8cd863 178 Gene3D G3DSA:1.10.760.10 79 178 5.3E-17 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CIG75_RS07630 ad3eb53a2857f9faae8ca2484d8cd863 178 SUPERFAMILY SSF46626 70 177 8.76E-20 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CIG75_RS07630 ad3eb53a2857f9faae8ca2484d8cd863 178 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 102 174 5.7E-8 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CIG75_RS13215 1517a73c70094226216275ff618e9c9c 240 TIGRFAM TIGR02835 spore_sigmaE: RNA polymerase sigma-E factor 11 239 7.9E-130 T 28-03-2018 IPR014200 RNA polymerase sigma-E type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS13215 1517a73c70094226216275ff618e9c9c 240 PRINTS PR00046 Major sigma-70 factor signature 185 197 5.6E-12 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS13215 1517a73c70094226216275ff618e9c9c 240 PRINTS PR00046 Major sigma-70 factor signature 87 100 5.6E-12 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS13215 1517a73c70094226216275ff618e9c9c 240 PRINTS PR00046 Major sigma-70 factor signature 206 221 5.6E-12 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS13215 1517a73c70094226216275ff618e9c9c 240 PRINTS PR00046 Major sigma-70 factor signature 221 232 5.6E-12 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS13215 1517a73c70094226216275ff618e9c9c 240 Gene3D G3DSA:1.10.1270.10 154 240 2.9E-23 T 28-03-2018 CIG75_RS13215 1517a73c70094226216275ff618e9c9c 240 Gene3D G3DSA:1.10.601.10 35 131 3.0E-29 T 28-03-2018 CIG75_RS13215 1517a73c70094226216275ff618e9c9c 240 Pfam PF04545 Sigma-70, region 4 181 234 1.1E-16 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS13215 1517a73c70094226216275ff618e9c9c 240 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 87 100 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS13215 1517a73c70094226216275ff618e9c9c 240 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 61 235 4.2E-36 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS13215 1517a73c70094226216275ff618e9c9c 240 SUPERFAMILY SSF88659 144 238 1.23E-23 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS13215 1517a73c70094226216275ff618e9c9c 240 SUPERFAMILY SSF88946 27 132 4.24E-33 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS13215 1517a73c70094226216275ff618e9c9c 240 Pfam PF04542 Sigma-70 region 2 63 132 5.8E-19 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS13215 1517a73c70094226216275ff618e9c9c 240 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 206 232 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS13215 1517a73c70094226216275ff618e9c9c 240 PIRSF PIRSF000770 12 240 1.9E-72 T 28-03-2018 CIG75_RS04175 970ac13906e2b0d81ba25afd0be24575 430 PRINTS PR00758 Arsenical pump membrane protein signature 178 201 2.6E-106 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CIG75_RS04175 970ac13906e2b0d81ba25afd0be24575 430 PRINTS PR00758 Arsenical pump membrane protein signature 365 390 2.6E-106 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CIG75_RS04175 970ac13906e2b0d81ba25afd0be24575 430 PRINTS PR00758 Arsenical pump membrane protein signature 218 243 2.6E-106 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CIG75_RS04175 970ac13906e2b0d81ba25afd0be24575 430 PRINTS PR00758 Arsenical pump membrane protein signature 279 303 2.6E-106 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CIG75_RS04175 970ac13906e2b0d81ba25afd0be24575 430 PRINTS PR00758 Arsenical pump membrane protein signature 145 169 2.6E-106 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CIG75_RS04175 970ac13906e2b0d81ba25afd0be24575 430 PRINTS PR00758 Arsenical pump membrane protein signature 324 346 2.6E-106 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CIG75_RS04175 970ac13906e2b0d81ba25afd0be24575 430 PRINTS PR00758 Arsenical pump membrane protein signature 102 126 2.6E-106 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CIG75_RS04175 970ac13906e2b0d81ba25afd0be24575 430 PRINTS PR00758 Arsenical pump membrane protein signature 398 422 2.6E-106 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CIG75_RS04175 970ac13906e2b0d81ba25afd0be24575 430 Pfam PF02040 Arsenical pump membrane protein 4 426 2.2E-199 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CIG75_RS04175 970ac13906e2b0d81ba25afd0be24575 430 TIGRFAM TIGR00935 2a45: arsenite/antimonite efflux pump membrane protein 4 427 2.1E-212 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CIG75_RS01700 f4ce4e464e649bbfc685e0fab67d7d34 539 Gene3D G3DSA:3.90.700.10 247 340 1.4E-33 T 28-03-2018 CIG75_RS01700 f4ce4e464e649bbfc685e0fab67d7d34 539 SUPERFAMILY SSF56425 240 354 2.24E-42 T 28-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CIG75_RS01700 f4ce4e464e649bbfc685e0fab67d7d34 539 Pfam PF00890 FAD binding domain 20 394 4.8E-92 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CIG75_RS01700 f4ce4e464e649bbfc685e0fab67d7d34 539 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 18 516 2.7E-167 T 28-03-2018 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 CIG75_RS01700 f4ce4e464e649bbfc685e0fab67d7d34 539 Gene3D G3DSA:3.50.50.60 341 417 2.8E-14 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS01700 f4ce4e464e649bbfc685e0fab67d7d34 539 SUPERFAMILY SSF46977 437 533 1.14E-26 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CIG75_RS01700 f4ce4e464e649bbfc685e0fab67d7d34 539 PIRSF PIRSF000171 9 536 1.3E-37 T 28-03-2018 CIG75_RS01700 f4ce4e464e649bbfc685e0fab67d7d34 539 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 21 40 2.7E-6 T 28-03-2018 CIG75_RS01700 f4ce4e464e649bbfc685e0fab67d7d34 539 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 357 379 2.7E-6 T 28-03-2018 CIG75_RS01700 f4ce4e464e649bbfc685e0fab67d7d34 539 Gene3D G3DSA:1.20.58.100 427 536 5.7E-24 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CIG75_RS01700 f4ce4e464e649bbfc685e0fab67d7d34 539 Pfam PF02910 Fumarate reductase flavoprotein C-term 440 530 2.6E-15 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CIG75_RS01700 f4ce4e464e649bbfc685e0fab67d7d34 539 Gene3D G3DSA:3.50.50.60 7 214 4.9E-16 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS01700 f4ce4e464e649bbfc685e0fab67d7d34 539 SUPERFAMILY SSF51905 13 266 4.45E-64 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS01700 f4ce4e464e649bbfc685e0fab67d7d34 539 SUPERFAMILY SSF51905 358 416 4.45E-64 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS19760 9f6ef3160e3d8f39c7e0476f11a9b17f 139 PRINTS PR01034 Ribosomal protein S12 signature 40 55 1.1E-59 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS19760 9f6ef3160e3d8f39c7e0476f11a9b17f 139 PRINTS PR01034 Ribosomal protein S12 signature 55 70 1.1E-59 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS19760 9f6ef3160e3d8f39c7e0476f11a9b17f 139 PRINTS PR01034 Ribosomal protein S12 signature 107 123 1.1E-59 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS19760 9f6ef3160e3d8f39c7e0476f11a9b17f 139 PRINTS PR01034 Ribosomal protein S12 signature 90 107 1.1E-59 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS19760 9f6ef3160e3d8f39c7e0476f11a9b17f 139 PRINTS PR01034 Ribosomal protein S12 signature 71 90 1.1E-59 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS19760 9f6ef3160e3d8f39c7e0476f11a9b17f 139 PRINTS PR01034 Ribosomal protein S12 signature 123 135 1.1E-59 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS19760 9f6ef3160e3d8f39c7e0476f11a9b17f 139 SUPERFAMILY SSF50249 2 137 1.2E-48 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CIG75_RS19760 9f6ef3160e3d8f39c7e0476f11a9b17f 139 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 137 1.1E-68 T 28-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS19760 9f6ef3160e3d8f39c7e0476f11a9b17f 139 PIRSF PIRSF002133 1 137 7.2E-49 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS19760 9f6ef3160e3d8f39c7e0476f11a9b17f 139 Gene3D G3DSA:2.40.50.140 1 139 3.5E-65 T 28-03-2018 CIG75_RS19760 9f6ef3160e3d8f39c7e0476f11a9b17f 139 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 136 41.185 T 28-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS19760 9f6ef3160e3d8f39c7e0476f11a9b17f 139 Pfam PF00164 Ribosomal protein S12/S23 40 136 2.2E-38 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS19760 9f6ef3160e3d8f39c7e0476f11a9b17f 139 ProSitePatterns PS00055 Ribosomal protein S12 signature. 56 63 - T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS01115 2e470fb3517013d02cfd7aa1813f94c4 238 Gene3D G3DSA:3.30.70.580 76 146 1.4E-15 T 28-03-2018 CIG75_RS01115 2e470fb3517013d02cfd7aa1813f94c4 238 SMART SM00363 1 67 3.1E-6 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CIG75_RS01115 2e470fb3517013d02cfd7aa1813f94c4 238 Pfam PF00849 RNA pseudouridylate synthase 68 194 1.3E-14 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CIG75_RS01115 2e470fb3517013d02cfd7aa1813f94c4 238 Pfam PF01479 S4 domain 1 34 1.4E-8 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CIG75_RS01115 2e470fb3517013d02cfd7aa1813f94c4 238 Gene3D G3DSA:3.10.290.10 1 75 1.2E-13 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CIG75_RS01115 2e470fb3517013d02cfd7aa1813f94c4 238 SUPERFAMILY SSF55174 1 53 1.46E-12 T 28-03-2018 CIG75_RS01115 2e470fb3517013d02cfd7aa1813f94c4 238 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 103 117 - T 28-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 CIG75_RS01115 2e470fb3517013d02cfd7aa1813f94c4 238 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 72 224 4.3E-48 T 28-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 CIG75_RS01115 2e470fb3517013d02cfd7aa1813f94c4 238 Gene3D G3DSA:3.30.70.1560 147 211 6.6E-25 T 28-03-2018 CIG75_RS01115 2e470fb3517013d02cfd7aa1813f94c4 238 SUPERFAMILY SSF55120 67 228 3.29E-38 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CIG75_RS00440 bbb777ec8af16f9eaafae1d3a036dd05 185 Gene3D G3DSA:2.70.70.10 36 166 4.7E-31 T 28-03-2018 CIG75_RS00440 bbb777ec8af16f9eaafae1d3a036dd05 185 Pfam PF01551 Peptidase family M23 66 153 8.1E-27 T 28-03-2018 IPR016047 Peptidase M23 CIG75_RS00440 bbb777ec8af16f9eaafae1d3a036dd05 185 SUPERFAMILY SSF51261 48 155 3.03E-34 T 28-03-2018 IPR011055 Duplicated hybrid motif CIG75_RS19675 12b61bce4a12e04fdda710b1f2710750 181 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 2 180 44.082 T 28-03-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS19675 12b61bce4a12e04fdda710b1f2710750 181 SUPERFAMILY SSF55282 4 179 1.72E-77 T 28-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CIG75_RS19675 12b61bce4a12e04fdda710b1f2710750 181 PIRSF PIRSF002161 2 181 1.1E-65 T 28-03-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CIG75_RS19675 12b61bce4a12e04fdda710b1f2710750 181 Gene3D G3DSA:3.30.1440.10 2 180 8.7E-79 T 28-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CIG75_RS19675 12b61bce4a12e04fdda710b1f2710750 181 Pfam PF00673 ribosomal L5P family C-terminus 85 178 3.4E-39 T 28-03-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CIG75_RS19675 12b61bce4a12e04fdda710b1f2710750 181 ProSitePatterns PS00358 Ribosomal protein L5 signature. 58 74 - T 28-03-2018 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CIG75_RS19675 12b61bce4a12e04fdda710b1f2710750 181 Pfam PF00281 Ribosomal protein L5 25 81 5.1E-28 T 28-03-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CIG75_RS03700 747809342fa7f66875d8d7c76ee7bc02 426 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 421 7.3E-151 T 28-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CIG75_RS03700 747809342fa7f66875d8d7c76ee7bc02 426 Gene3D G3DSA:3.65.10.10 21 223 2.0E-39 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CIG75_RS03700 747809342fa7f66875d8d7c76ee7bc02 426 Gene3D G3DSA:3.65.10.10 224 425 1.6E-42 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CIG75_RS03700 747809342fa7f66875d8d7c76ee7bc02 426 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 422 39.036 T 28-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CIG75_RS03700 747809342fa7f66875d8d7c76ee7bc02 426 SUPERFAMILY SSF55205 1 422 6.21E-121 T 28-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CIG75_RS03700 747809342fa7f66875d8d7c76ee7bc02 426 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 410 4.5E-82 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CIG75_RS07750 74b2dd71777765bd01fdba4d619df77b 249 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 9 116 4.0E-28 T 28-03-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CIG75_RS07750 74b2dd71777765bd01fdba4d619df77b 249 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 11 232 3.0E-41 T 28-03-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CIG75_RS07750 74b2dd71777765bd01fdba4d619df77b 249 Gene3D G3DSA:3.10.20.30 1 111 1.5E-24 T 28-03-2018 IPR012675 Beta-grasp domain CIG75_RS07750 74b2dd71777765bd01fdba4d619df77b 249 Gene3D G3DSA:1.10.1060.10 112 243 1.3E-18 T 28-03-2018 CIG75_RS07750 74b2dd71777765bd01fdba4d619df77b 249 SUPERFAMILY SSF46548 113 238 3.31E-27 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CIG75_RS07750 74b2dd71777765bd01fdba4d619df77b 249 SUPERFAMILY SSF54292 5 111 3.56E-21 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CIG75_RS07750 74b2dd71777765bd01fdba4d619df77b 249 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 154 165 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CIG75_RS07750 74b2dd71777765bd01fdba4d619df77b 249 Pfam PF13183 4Fe-4S dicluster domain 150 225 9.5E-10 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CIG75_RS01000 5176f32ba820424c17ba981ec83b5cc8 486 TIGRFAM TIGR01513 NAPRTase_put: nicotinate phosphoribosyltransferase 8 465 9.8E-171 T 28-03-2018 IPR006405 Nicotinate phosphoribosyltransferase pncB-type GO:0004516|GO:0019358 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264|Reactome: R-HSA-6798695 CIG75_RS01000 5176f32ba820424c17ba981ec83b5cc8 486 SUPERFAMILY SSF51690 138 479 1.67E-114 T 28-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CIG75_RS01000 5176f32ba820424c17ba981ec83b5cc8 486 PIRSF PIRSF000484 1 481 1.7E-146 T 28-03-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 CIG75_RS01000 5176f32ba820424c17ba981ec83b5cc8 486 SUPERFAMILY SSF54675 2 137 1.08E-42 T 28-03-2018 CIG75_RS01000 5176f32ba820424c17ba981ec83b5cc8 486 Gene3D G3DSA:3.20.140.10 2 388 1.9E-123 T 28-03-2018 CIG75_RS01000 5176f32ba820424c17ba981ec83b5cc8 486 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 156 357 2.3E-12 T 28-03-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 CIG75_RS18895 1ee738d7cbd4520d1160dd0a3b1d95ef 131 Pfam PF05105 Bacteriophage holin family 16 125 9.2E-38 T 28-03-2018 IPR006480 Bacteriophage holin family CIG75_RS18895 1ee738d7cbd4520d1160dd0a3b1d95ef 131 TIGRFAM TIGR01593 holin_tox_secr: toxin secretion/phage lysis holin 13 127 2.1E-28 T 28-03-2018 IPR006480 Bacteriophage holin family CIG75_RS15275 6b291740ec252db773a9ccde3cf15bf9 594 Gene3D G3DSA:3.40.50.2000 414 533 0.011 T 28-03-2018 CIG75_RS15275 6b291740ec252db773a9ccde3cf15bf9 594 SUPERFAMILY SSF102114 174 397 4.71E-35 T 28-03-2018 CIG75_RS15275 6b291740ec252db773a9ccde3cf15bf9 594 Pfam PF02310 B12 binding domain 9 123 4.0E-18 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CIG75_RS15275 6b291740ec252db773a9ccde3cf15bf9 594 SMART SM00729 177 392 1.5E-18 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CIG75_RS15275 6b291740ec252db773a9ccde3cf15bf9 594 Gene3D G3DSA:3.40.50.280 1 123 4.1E-13 T 28-03-2018 CIG75_RS15275 6b291740ec252db773a9ccde3cf15bf9 594 Pfam PF13311 Protein of unknown function (DUF4080) 374 551 1.2E-44 T 28-03-2018 IPR025288 Domain of unknown function DUF4080 CIG75_RS15275 6b291740ec252db773a9ccde3cf15bf9 594 Pfam PF04055 Radical SAM superfamily 183 347 1.1E-14 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CIG75_RS15275 6b291740ec252db773a9ccde3cf15bf9 594 SUPERFAMILY SSF52242 44 132 1.88E-9 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CIG75_RS15275 6b291740ec252db773a9ccde3cf15bf9 594 Gene3D G3DSA:3.20.20.70 124 413 4.3E-23 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CIG75_RS20095 83f14d436d792619e1a4057951663d9d 178 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 10 137 2.2E-37 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CIG75_RS20095 83f14d436d792619e1a4057951663d9d 178 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 93 104 - T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CIG75_RS20095 83f14d436d792619e1a4057951663d9d 178 SUPERFAMILY SSF55083 7 160 6.93E-55 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CIG75_RS20095 83f14d436d792619e1a4057951663d9d 178 Gene3D G3DSA:3.30.70.560 5 164 2.3E-61 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CIG75_RS20095 83f14d436d792619e1a4057951663d9d 178 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 9 137 4.9E-43 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CIG75_RS17925 4c9a2ef71ec1b0356a43595928ab226e 874 SUPERFAMILY SSF55681 2 239 6.71E-93 T 28-03-2018 CIG75_RS17925 4c9a2ef71ec1b0356a43595928ab226e 874 Gene3D G3DSA:3.30.980.10 550 707 6.6E-46 T 28-03-2018 CIG75_RS17925 4c9a2ef71ec1b0356a43595928ab226e 874 SUPERFAMILY SSF50447 450 547 3.88E-16 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CIG75_RS17925 4c9a2ef71ec1b0356a43595928ab226e 874 Gene3D G3DSA:1.20.5.170 708 868 4.1E-4 T 28-03-2018 CIG75_RS17925 4c9a2ef71ec1b0356a43595928ab226e 874 Gene3D G3DSA:3.30.930.10 1 236 2.1E-104 T 28-03-2018 CIG75_RS17925 4c9a2ef71ec1b0356a43595928ab226e 874 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 5 853 0.0 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CIG75_RS17925 4c9a2ef71ec1b0356a43595928ab226e 874 SMART SM00863 650 693 6.0E-21 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CIG75_RS17925 4c9a2ef71ec1b0356a43595928ab226e 874 SUPERFAMILY SSF55186 549 708 9.81E-52 T 28-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 CIG75_RS17925 4c9a2ef71ec1b0356a43595928ab226e 874 PRINTS PR00980 Alanyl-tRNA synthetase signature 220 233 5.5E-30 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CIG75_RS17925 4c9a2ef71ec1b0356a43595928ab226e 874 PRINTS PR00980 Alanyl-tRNA synthetase signature 270 286 5.5E-30 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CIG75_RS17925 4c9a2ef71ec1b0356a43595928ab226e 874 PRINTS PR00980 Alanyl-tRNA synthetase signature 294 307 5.5E-30 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CIG75_RS17925 4c9a2ef71ec1b0356a43595928ab226e 874 PRINTS PR00980 Alanyl-tRNA synthetase signature 193 204 5.5E-30 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CIG75_RS17925 4c9a2ef71ec1b0356a43595928ab226e 874 PRINTS PR00980 Alanyl-tRNA synthetase signature 70 81 5.5E-30 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CIG75_RS17925 4c9a2ef71ec1b0356a43595928ab226e 874 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 874 184.775 T 28-03-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 CIG75_RS17925 4c9a2ef71ec1b0356a43595928ab226e 874 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 650 693 6.1E-18 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CIG75_RS17925 4c9a2ef71ec1b0356a43595928ab226e 874 SUPERFAMILY SSF101353 240 440 3.4E-67 T 28-03-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 CIG75_RS17925 4c9a2ef71ec1b0356a43595928ab226e 874 Pfam PF01411 tRNA synthetases class II (A) 5 553 5.9E-211 T 28-03-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 CIG75_RS17925 4c9a2ef71ec1b0356a43595928ab226e 874 Pfam PF02272 DHHA1 domain 730 868 1.5E-28 T 28-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CIG75_RS14640 42497c8bca7bc3a477cc746a0d20a415 379 Gene3D G3DSA:1.20.140.10 218 378 3.7E-63 T 28-03-2018 CIG75_RS14640 42497c8bca7bc3a477cc746a0d20a415 379 Gene3D G3DSA:2.40.110.10 123 217 4.0E-39 T 28-03-2018 CIG75_RS14640 42497c8bca7bc3a477cc746a0d20a415 379 SUPERFAMILY SSF56645 2 242 1.13E-86 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CIG75_RS14640 42497c8bca7bc3a477cc746a0d20a415 379 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 217 4.2E-25 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CIG75_RS14640 42497c8bca7bc3a477cc746a0d20a415 379 SUPERFAMILY SSF47203 228 377 1.23E-61 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CIG75_RS14640 42497c8bca7bc3a477cc746a0d20a415 379 PIRSF PIRSF016578 5 367 2.2E-24 T 28-03-2018 CIG75_RS14640 42497c8bca7bc3a477cc746a0d20a415 379 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 377 2.3E-54 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CIG75_RS14640 42497c8bca7bc3a477cc746a0d20a415 379 Gene3D G3DSA:1.10.540.10 1 122 3.1E-39 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CIG75_RS14640 42497c8bca7bc3a477cc746a0d20a415 379 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 124 136 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CIG75_RS14640 42497c8bca7bc3a477cc746a0d20a415 379 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 118 3.6E-37 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CIG75_RS14640 42497c8bca7bc3a477cc746a0d20a415 379 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 336 355 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CIG75_RS08430 4d9d665cfc0ca0338af69c500e18d85f 309 SMART SM00729 68 273 4.0E-17 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CIG75_RS08430 4d9d665cfc0ca0338af69c500e18d85f 309 Gene3D G3DSA:3.20.20.70 12 299 1.2E-23 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CIG75_RS08430 4d9d665cfc0ca0338af69c500e18d85f 309 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 15 57 1.2E-11 T 28-03-2018 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CIG75_RS08430 4d9d665cfc0ca0338af69c500e18d85f 309 SUPERFAMILY SSF102114 32 297 1.83E-65 T 28-03-2018 CIG75_RS08430 4d9d665cfc0ca0338af69c500e18d85f 309 Pfam PF04055 Radical SAM superfamily 75 234 8.4E-14 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CIG75_RS08430 4d9d665cfc0ca0338af69c500e18d85f 309 Hamap MF_00206 Lipoyl synthase [lipA]. 1 307 141.718 T 28-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CIG75_RS08430 4d9d665cfc0ca0338af69c500e18d85f 309 PIRSF PIRSF005963 2 309 1.5E-135 T 28-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CIG75_RS08430 4d9d665cfc0ca0338af69c500e18d85f 309 TIGRFAM TIGR00510 lipA: lipoyl synthase 14 301 1.7E-117 T 28-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CIG75_RS00525 ccd9751110814a33fbc4c0db4a8b70f9 132 Pfam PF08241 Methyltransferase domain 27 123 1.1E-22 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CIG75_RS00525 ccd9751110814a33fbc4c0db4a8b70f9 132 Gene3D G3DSA:3.40.50.150 4 131 8.8E-30 T 28-03-2018 CIG75_RS00525 ccd9751110814a33fbc4c0db4a8b70f9 132 SUPERFAMILY SSF53335 14 126 8.59E-32 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CIG75_RS09640 fb8db7b763a277fa83d74574627982c9 202 Gene3D G3DSA:3.40.50.1950 3 202 4.9E-54 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CIG75_RS09640 fb8db7b763a277fa83d74574627982c9 202 Pfam PF02441 Flavoprotein 4 177 6.5E-28 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CIG75_RS09640 fb8db7b763a277fa83d74574627982c9 202 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 5 196 4.1E-59 T 28-03-2018 IPR004507 Flavin prenyltransferase UbiX/Pad1 CIG75_RS09640 fb8db7b763a277fa83d74574627982c9 202 SUPERFAMILY SSF52507 3 198 1.57E-58 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CIG75_RS09640 fb8db7b763a277fa83d74574627982c9 202 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 3 198 35.491 T 28-03-2018 IPR004507 Flavin prenyltransferase UbiX/Pad1 CIG75_RS19845 21a744d3bc98095f52ea451c9af75134 483 Gene3D G3DSA:1.10.8.70 334 379 4.3E-4 T 28-03-2018 IPR020752 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 1 GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 CIG75_RS19845 21a744d3bc98095f52ea451c9af75134 483 Gene3D G3DSA:3.40.50.620 128 246 4.8E-32 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CIG75_RS19845 21a744d3bc98095f52ea451c9af75134 483 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 5 481 2.5E-180 T 28-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CIG75_RS19845 21a744d3bc98095f52ea451c9af75134 483 Gene3D G3DSA:1.10.10.350 383 482 2.0E-28 T 28-03-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CIG75_RS19845 21a744d3bc98095f52ea451c9af75134 483 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 11 22 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CIG75_RS19845 21a744d3bc98095f52ea451c9af75134 483 PRINTS PR00987 Glutamyl-tRNA synthetase signature 194 204 5.5E-28 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CIG75_RS19845 21a744d3bc98095f52ea451c9af75134 483 PRINTS PR00987 Glutamyl-tRNA synthetase signature 37 50 5.5E-28 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CIG75_RS19845 21a744d3bc98095f52ea451c9af75134 483 PRINTS PR00987 Glutamyl-tRNA synthetase signature 22 33 5.5E-28 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CIG75_RS19845 21a744d3bc98095f52ea451c9af75134 483 PRINTS PR00987 Glutamyl-tRNA synthetase signature 8 20 5.5E-28 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CIG75_RS19845 21a744d3bc98095f52ea451c9af75134 483 PRINTS PR00987 Glutamyl-tRNA synthetase signature 210 218 5.5E-28 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CIG75_RS19845 21a744d3bc98095f52ea451c9af75134 483 Gene3D G3DSA:3.40.50.620 5 127 1.7E-36 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CIG75_RS19845 21a744d3bc98095f52ea451c9af75134 483 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 5 323 3.0E-116 T 28-03-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 CIG75_RS19845 21a744d3bc98095f52ea451c9af75134 483 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 4 481 34.48 T 28-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CIG75_RS19845 21a744d3bc98095f52ea451c9af75134 483 Gene3D G3DSA:1.10.1160.10 247 333 5.1E-33 T 28-03-2018 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 CIG75_RS19845 21a744d3bc98095f52ea451c9af75134 483 SUPERFAMILY SSF48163 317 480 3.92E-46 T 28-03-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CIG75_RS19845 21a744d3bc98095f52ea451c9af75134 483 SUPERFAMILY SSF52374 5 316 4.83E-117 T 28-03-2018 CIG75_RS13885 d2b87f1238d4d355a32b228c72145500 313 ProSitePatterns PS01016 Glycoprotease family signature. 96 116 - T 28-03-2018 IPR017860 Peptidase M22, conserved site KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618|Reactome: R-HSA-6782315 CIG75_RS13885 d2b87f1238d4d355a32b228c72145500 313 SUPERFAMILY SSF53067 1 304 7.54E-26 T 28-03-2018 CIG75_RS13885 d2b87f1238d4d355a32b228c72145500 313 Gene3D G3DSA:3.30.420.40 1 140 5.2E-14 T 28-03-2018 CIG75_RS13885 d2b87f1238d4d355a32b228c72145500 313 Gene3D G3DSA:3.30.420.40 141 286 7.9E-19 T 28-03-2018 CIG75_RS13885 d2b87f1238d4d355a32b228c72145500 313 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 97 116 4.6E-14 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CIG75_RS13885 d2b87f1238d4d355a32b228c72145500 313 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 158 179 4.6E-14 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CIG75_RS13885 d2b87f1238d4d355a32b228c72145500 313 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 260 269 4.6E-14 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CIG75_RS13885 d2b87f1238d4d355a32b228c72145500 313 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 4 17 4.6E-14 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CIG75_RS13885 d2b87f1238d4d355a32b228c72145500 313 Pfam PF00814 Glycoprotease family 49 302 2.4E-35 T 28-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CIG75_RS07595 cf9a85d3ca522dd35fbfcfdd96533948 363 TIGRFAM TIGR01361 DAHP_synth_Bsub: 3-deoxy-7-phosphoheptulonate synthase 95 351 8.2E-116 T 28-03-2018 IPR006268 Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2 GO:0009073|GO:0016832 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 CIG75_RS07595 cf9a85d3ca522dd35fbfcfdd96533948 363 Pfam PF01817 Chorismate mutase type II 10 83 2.7E-17 T 28-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CIG75_RS07595 cf9a85d3ca522dd35fbfcfdd96533948 363 SMART SM00830 10 89 7.2E-17 T 28-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CIG75_RS07595 cf9a85d3ca522dd35fbfcfdd96533948 363 Pfam PF00793 DAHP synthetase I family 110 350 1.6E-77 T 28-03-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 CIG75_RS07595 cf9a85d3ca522dd35fbfcfdd96533948 363 SUPERFAMILY SSF51569 86 351 2.01E-95 T 28-03-2018 CIG75_RS07595 cf9a85d3ca522dd35fbfcfdd96533948 363 SUPERFAMILY SSF48600 5 83 4.58E-18 T 28-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CIG75_RS07595 cf9a85d3ca522dd35fbfcfdd96533948 363 Gene3D G3DSA:1.20.59.10 4 90 5.6E-21 T 28-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CIG75_RS07595 cf9a85d3ca522dd35fbfcfdd96533948 363 Gene3D G3DSA:3.20.20.70 94 353 4.5E-72 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CIG75_RS07595 cf9a85d3ca522dd35fbfcfdd96533948 363 TIGRFAM TIGR01801 CM_A: chorismate mutase 1 99 1.4E-33 T 28-03-2018 IPR010954 Chorismate mutase, Firmicutes/Deinococcus KEGG: 00400+2.5.1.54+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6164|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CIG75_RS19535 6f3d02ce31454016ca2f64bcace3c574 237 Pfam PF01944 Stage II sporulation protein M 54 226 7.6E-29 T 28-03-2018 IPR002798 Stage II sporulation protein M-like CIG75_RS11470 363cde6a4fbccd726f5e71cd4f0c81be 303 SUPERFAMILY SSF54506 4 301 1.57E-68 T 28-03-2018 CIG75_RS11470 363cde6a4fbccd726f5e71cd4f0c81be 303 Gene3D G3DSA:3.10.310.10 1 135 1.1E-31 T 28-03-2018 CIG75_RS11470 363cde6a4fbccd726f5e71cd4f0c81be 303 Pfam PF02567 Phenazine biosynthesis-like protein 10 299 9.3E-74 T 28-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CIG75_RS11470 363cde6a4fbccd726f5e71cd4f0c81be 303 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 4 301 4.2E-77 T 28-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CIG75_RS11470 363cde6a4fbccd726f5e71cd4f0c81be 303 PIRSF PIRSF016184 2 303 2.6E-87 T 28-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CIG75_RS11470 363cde6a4fbccd726f5e71cd4f0c81be 303 Gene3D G3DSA:3.10.310.10 136 292 2.7E-41 T 28-03-2018 CIG75_RS07760 d01583f43a59f341a67c2bb12cfa9360 75 SUPERFAMILY SSF46894 10 72 2.01E-22 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CIG75_RS07760 d01583f43a59f341a67c2bb12cfa9360 75 SMART SM00421 10 67 2.6E-24 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CIG75_RS07760 d01583f43a59f341a67c2bb12cfa9360 75 ProSitePatterns PS00622 LuxR-type HTH domain signature. 27 54 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CIG75_RS07760 d01583f43a59f341a67c2bb12cfa9360 75 Gene3D G3DSA:1.10.10.10 2 75 1.9E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS07760 d01583f43a59f341a67c2bb12cfa9360 75 Pfam PF00196 Bacterial regulatory proteins, luxR family 12 65 1.1E-23 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CIG75_RS07760 d01583f43a59f341a67c2bb12cfa9360 75 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 13 27 7.6E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CIG75_RS07760 d01583f43a59f341a67c2bb12cfa9360 75 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 27 43 7.6E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CIG75_RS07760 d01583f43a59f341a67c2bb12cfa9360 75 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 43 55 7.6E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CIG75_RS06255 c314f39748a8cd70caa0a683dad95538 343 SUPERFAMILY SSF55021 248 342 3.09E-19 T 28-03-2018 CIG75_RS06255 c314f39748a8cd70caa0a683dad95538 343 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS06255 c314f39748a8cd70caa0a683dad95538 343 SMART SM00930 267 342 1.5E-18 T 28-03-2018 IPR018449 NIL domain CIG75_RS06255 c314f39748a8cd70caa0a683dad95538 343 Gene3D G3DSA:3.40.50.300 1 261 2.8E-79 T 28-03-2018 CIG75_RS06255 c314f39748a8cd70caa0a683dad95538 343 Gene3D G3DSA:3.30.70.260 262 343 6.6E-21 T 28-03-2018 CIG75_RS06255 c314f39748a8cd70caa0a683dad95538 343 Pfam PF00005 ABC transporter 22 169 3.6E-38 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS06255 c314f39748a8cd70caa0a683dad95538 343 SMART SM00382 30 233 4.8E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS06255 c314f39748a8cd70caa0a683dad95538 343 SUPERFAMILY SSF52540 1 240 1.15E-83 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS06255 c314f39748a8cd70caa0a683dad95538 343 Pfam PF09383 NIL domain 270 341 2.1E-17 T 28-03-2018 IPR018449 NIL domain CIG75_RS17580 9a60a71d57cc48516947e75394a7d3e1 349 Gene3D G3DSA:2.40.50.100 61 126 3.0E-13 T 28-03-2018 CIG75_RS17580 9a60a71d57cc48516947e75394a7d3e1 349 Gene3D G3DSA:2.40.50.100 153 315 7.0E-4 T 28-03-2018 CIG75_RS17580 9a60a71d57cc48516947e75394a7d3e1 349 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 32 349 4.1E-42 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 CIG75_RS17580 9a60a71d57cc48516947e75394a7d3e1 349 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 53 267 1.6E-23 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CIG75_RS17580 9a60a71d57cc48516947e75394a7d3e1 349 SUPERFAMILY SSF111369 48 272 1.44E-14 T 28-03-2018 CIG75_RS05565 2ef8a116079c30e7ba9af9313b7640cb 142 Pfam PF03061 Thioesterase superfamily 19 101 7.3E-14 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CIG75_RS05565 2ef8a116079c30e7ba9af9313b7640cb 142 PIRSF PIRSF003230 1 138 7.4E-43 T 28-03-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 CIG75_RS05565 2ef8a116079c30e7ba9af9313b7640cb 142 ProSitePatterns PS01328 4-hydroxybenzoyl-CoA thioesterase family active site. 10 27 - T 28-03-2018 IPR008272 4-hydroxybenzoyl-CoA thioesterase, active site GO:0016787 CIG75_RS05565 2ef8a116079c30e7ba9af9313b7640cb 142 Gene3D G3DSA:3.10.129.10 1 142 2.2E-37 T 28-03-2018 CIG75_RS05565 2ef8a116079c30e7ba9af9313b7640cb 142 SUPERFAMILY SSF54637 4 131 7.24E-39 T 28-03-2018 IPR029069 HotDog domain CIG75_RS05565 2ef8a116079c30e7ba9af9313b7640cb 142 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 9 115 1.0E-29 T 28-03-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 CIG75_RS00255 6f89227e0abaaeb02e0c7c8a89b5d555 628 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 368 391 - T 28-03-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 CIG75_RS00255 6f89227e0abaaeb02e0c7c8a89b5d555 628 Pfam PF13932 GidA associated domain 401 614 7.3E-77 T 28-03-2018 IPR026904 GidA associated domain 3 Reactome: R-HSA-6787450 CIG75_RS00255 6f89227e0abaaeb02e0c7c8a89b5d555 628 Gene3D G3DSA:3.50.50.60 6 265 3.3E-70 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS00255 6f89227e0abaaeb02e0c7c8a89b5d555 628 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 273 287 - T 28-03-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 CIG75_RS00255 6f89227e0abaaeb02e0c7c8a89b5d555 628 SMART SM01228 544 615 7.3E-40 T 28-03-2018 CIG75_RS00255 6f89227e0abaaeb02e0c7c8a89b5d555 628 Pfam PF01134 Glucose inhibited division protein A 9 398 1.9E-165 T 28-03-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 CIG75_RS00255 6f89227e0abaaeb02e0c7c8a89b5d555 628 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 8 620 4.1E-276 T 28-03-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 CIG75_RS00255 6f89227e0abaaeb02e0c7c8a89b5d555 628 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 6 622 41.978 T 28-03-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 CIG75_RS00255 6f89227e0abaaeb02e0c7c8a89b5d555 628 SUPERFAMILY SSF51905 98 261 1.76E-45 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS00255 6f89227e0abaaeb02e0c7c8a89b5d555 628 SUPERFAMILY SSF51905 7 67 1.76E-45 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS00255 6f89227e0abaaeb02e0c7c8a89b5d555 628 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 152 161 3.8E-5 T 28-03-2018 CIG75_RS00255 6f89227e0abaaeb02e0c7c8a89b5d555 628 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 9 31 3.8E-5 T 28-03-2018 CIG75_RS04235 fde1c23ad0e2abaaf29acf733b1ebc4e 442 SUPERFAMILY SSF48452 161 349 3.25E-15 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS04235 fde1c23ad0e2abaaf29acf733b1ebc4e 442 Pfam PF13424 Tetratricopeptide repeat 324 395 2.2E-7 T 28-03-2018 CIG75_RS04235 fde1c23ad0e2abaaf29acf733b1ebc4e 442 Gene3D G3DSA:1.10.260.40 5 76 8.9E-15 T 28-03-2018 CIG75_RS04235 fde1c23ad0e2abaaf29acf733b1ebc4e 442 Gene3D G3DSA:1.25.40.10 326 402 0.0044 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS04235 fde1c23ad0e2abaaf29acf733b1ebc4e 442 SMART SM00530 16 70 7.8E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS04235 fde1c23ad0e2abaaf29acf733b1ebc4e 442 Gene3D G3DSA:1.10.150.200 271 325 2.5E-6 T 28-03-2018 CIG75_RS04235 fde1c23ad0e2abaaf29acf733b1ebc4e 442 SMART SM00028 241 274 81.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS04235 fde1c23ad0e2abaaf29acf733b1ebc4e 442 SMART SM00028 80 113 140.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS04235 fde1c23ad0e2abaaf29acf733b1ebc4e 442 SMART SM00028 321 354 85.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS04235 fde1c23ad0e2abaaf29acf733b1ebc4e 442 SMART SM00028 403 435 170.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS04235 fde1c23ad0e2abaaf29acf733b1ebc4e 442 SMART SM00028 160 193 240.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS04235 fde1c23ad0e2abaaf29acf733b1ebc4e 442 SMART SM00028 201 234 0.064 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS04235 fde1c23ad0e2abaaf29acf733b1ebc4e 442 SMART SM00028 281 314 1.1 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS04235 fde1c23ad0e2abaaf29acf733b1ebc4e 442 Gene3D G3DSA:1.25.40.10 215 270 4.3E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS04235 fde1c23ad0e2abaaf29acf733b1ebc4e 442 Gene3D G3DSA:1.25.40.10 77 214 3.1E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS04235 fde1c23ad0e2abaaf29acf733b1ebc4e 442 SUPERFAMILY SSF47413 13 70 2.73E-12 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CIG75_RS04235 fde1c23ad0e2abaaf29acf733b1ebc4e 442 Pfam PF01381 Helix-turn-helix 17 70 1.3E-11 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS04235 fde1c23ad0e2abaaf29acf733b1ebc4e 442 Pfam PF13181 Tetratricopeptide repeat 202 232 0.075 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS04235 fde1c23ad0e2abaaf29acf733b1ebc4e 442 Gene3D G3DSA:1.25.40.10 403 437 0.24 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS01970 bb3d362fdf68c247030458a18599e960 367 SUPERFAMILY SSF56762 18 366 1.96E-120 T 28-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CIG75_RS01970 bb3d362fdf68c247030458a18599e960 367 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 1 367 46.362 T 28-03-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CIG75_RS01970 bb3d362fdf68c247030458a18599e960 367 Gene3D G3DSA:1.10.645.10 209 361 6.4E-34 T 28-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CIG75_RS01970 bb3d362fdf68c247030458a18599e960 367 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 122 292 2.0E-67 T 28-03-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CIG75_RS01970 bb3d362fdf68c247030458a18599e960 367 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 293 366 1.2E-24 T 28-03-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CIG75_RS01970 bb3d362fdf68c247030458a18599e960 367 Gene3D G3DSA:1.10.645.10 4 208 4.9E-53 T 28-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CIG75_RS13505 0eed055514cac2802b4d675561a45b21 462 SUPERFAMILY SSF53623 105 311 9.03E-54 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CIG75_RS13505 0eed055514cac2802b4d675561a45b21 462 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 31 461 5.9E-123 T 28-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CIG75_RS13505 0eed055514cac2802b4d675561a45b21 462 Gene3D G3DSA:3.90.190.20 314 462 2.2E-37 T 28-03-2018 CIG75_RS13505 0eed055514cac2802b4d675561a45b21 462 Gene3D G3DSA:3.40.1190.10 95 311 1.3E-62 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CIG75_RS13505 0eed055514cac2802b4d675561a45b21 462 SUPERFAMILY SSF53244 316 461 2.11E-27 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CIG75_RS13505 0eed055514cac2802b4d675561a45b21 462 SUPERFAMILY SSF63418 19 100 6.8E-22 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CIG75_RS13505 0eed055514cac2802b4d675561a45b21 462 Pfam PF02875 Mur ligase family, glutamate ligase domain 316 391 1.5E-12 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CIG75_RS13505 0eed055514cac2802b4d675561a45b21 462 Gene3D G3DSA:3.40.1390.10 1 94 7.6E-25 T 28-03-2018 CIG75_RS13505 0eed055514cac2802b4d675561a45b21 462 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 4 462 33.286 T 28-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CIG75_RS13505 0eed055514cac2802b4d675561a45b21 462 Pfam PF01225 Mur ligase family, catalytic domain 26 100 3.0E-7 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CIG75_RS13505 0eed055514cac2802b4d675561a45b21 462 Pfam PF08245 Mur ligase middle domain 110 294 2.0E-48 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CIG75_RS08985 6d35b2fe61672efab086ef19d4543b65 430 Gene3D G3DSA:1.10.150.200 239 281 5.1E-7 T 28-03-2018 CIG75_RS08985 6d35b2fe61672efab086ef19d4543b65 430 Gene3D G3DSA:1.10.150.200 181 238 1.4E-5 T 28-03-2018 CIG75_RS08985 6d35b2fe61672efab086ef19d4543b65 430 Gene3D G3DSA:1.10.260.40 1 83 3.1E-15 T 28-03-2018 CIG75_RS08985 6d35b2fe61672efab086ef19d4543b65 430 SMART SM00028 192 225 150.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS08985 6d35b2fe61672efab086ef19d4543b65 430 SMART SM00028 273 306 56.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS08985 6d35b2fe61672efab086ef19d4543b65 430 SMART SM00028 351 384 2.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS08985 6d35b2fe61672efab086ef19d4543b65 430 SMART SM00028 108 141 350.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS08985 6d35b2fe61672efab086ef19d4543b65 430 SMART SM00028 313 346 190.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS08985 6d35b2fe61672efab086ef19d4543b65 430 SMART SM00028 148 181 47.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS08985 6d35b2fe61672efab086ef19d4543b65 430 SMART SM00028 233 266 13.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS08985 6d35b2fe61672efab086ef19d4543b65 430 SUPERFAMILY SSF48452 210 418 2.09E-19 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS08985 6d35b2fe61672efab086ef19d4543b65 430 Pfam PF13176 Tetratricopeptide repeat 353 384 0.015 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS08985 6d35b2fe61672efab086ef19d4543b65 430 Pfam PF13181 Tetratricopeptide repeat 233 262 0.019 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS08985 6d35b2fe61672efab086ef19d4543b65 430 SMART SM00530 7 61 1.9E-11 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS08985 6d35b2fe61672efab086ef19d4543b65 430 Gene3D G3DSA:1.25.40.10 282 426 2.0E-15 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS08985 6d35b2fe61672efab086ef19d4543b65 430 Gene3D G3DSA:1.25.40.10 124 180 4.3E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS08985 6d35b2fe61672efab086ef19d4543b65 430 Gene3D G3DSA:1.25.40.10 84 123 5.3E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS08985 6d35b2fe61672efab086ef19d4543b65 430 Pfam PF01381 Helix-turn-helix 8 60 6.1E-11 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS08985 6d35b2fe61672efab086ef19d4543b65 430 SUPERFAMILY SSF48452 74 259 4.55E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS08985 6d35b2fe61672efab086ef19d4543b65 430 SUPERFAMILY SSF47413 3 62 1.74E-14 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CIG75_RS10910 d9f6105730acb671ef3225cefd9dc360 123 TIGRFAM TIGR01796 CM_mono_aroH: chorismate mutase 3 119 5.4E-47 T 28-03-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CIG75_RS10910 d9f6105730acb671ef3225cefd9dc360 123 PIRSF PIRSF005965 1 123 1.2E-49 T 28-03-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CIG75_RS10910 d9f6105730acb671ef3225cefd9dc360 123 Gene3D G3DSA:3.30.1330.40 3 120 7.3E-49 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CIG75_RS10910 d9f6105730acb671ef3225cefd9dc360 123 SUPERFAMILY SSF55298 1 121 3.22E-46 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CIG75_RS10910 d9f6105730acb671ef3225cefd9dc360 123 Pfam PF07736 Chorismate mutase type I 3 119 2.2E-47 T 28-03-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CIG75_RS10910 d9f6105730acb671ef3225cefd9dc360 123 ProDom PD031888 MUTASE CHORISMATE AROH THE CLASS ISOMERASE TRANSCRIPTION BIOSYNTHESIS CM 3D-STRUCTURE 9 119 1.0E-29 T 28-03-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CIG75_RS04375 77b283c78e591322ca6ce13fd434cb1c 511 SUPERFAMILY SSF117457 320 492 1.44E-51 T 28-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 CIG75_RS04375 77b283c78e591322ca6ce13fd434cb1c 511 Pfam PF05683 Fumarase C-terminus 307 494 9.9E-60 T 28-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 CIG75_RS04375 77b283c78e591322ca6ce13fd434cb1c 511 PIRSF PIRSF001394 1 511 4.9E-180 T 28-03-2018 IPR011167 Iron-dependent fumarate hydratase GO:0004333|GO:0006091 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384 CIG75_RS04375 77b283c78e591322ca6ce13fd434cb1c 511 Pfam PF05681 Fumarate hydratase (Fumerase) 6 281 3.0E-71 T 28-03-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 CIG75_RS04375 77b283c78e591322ca6ce13fd434cb1c 511 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 5 280 2.2E-62 T 28-03-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 CIG75_RS04375 77b283c78e591322ca6ce13fd434cb1c 511 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 330 492 3.7E-52 T 28-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 CIG75_RS04375 77b283c78e591322ca6ce13fd434cb1c 511 Gene3D G3DSA:3.20.130.10 318 493 3.6E-64 T 28-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 CIG75_RS04535 d75301b929b3601ffccfb0054f6ba4dc 175 Gene3D G3DSA:3.40.630.30 1 174 3.0E-27 T 28-03-2018 CIG75_RS04535 d75301b929b3601ffccfb0054f6ba4dc 175 Pfam PF13302 Acetyltransferase (GNAT) domain 4 146 2.2E-22 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CIG75_RS04535 d75301b929b3601ffccfb0054f6ba4dc 175 SUPERFAMILY SSF55729 2 170 3.12E-46 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CIG75_RS16395 c38d19900fd182696cf0010c9f264d5d 289 SUPERFAMILY SSF53850 92 287 4.5E-26 T 28-03-2018 CIG75_RS16395 c38d19900fd182696cf0010c9f264d5d 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.0E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CIG75_RS16395 c38d19900fd182696cf0010c9f264d5d 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.0E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CIG75_RS16395 c38d19900fd182696cf0010c9f264d5d 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.0E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CIG75_RS16395 c38d19900fd182696cf0010c9f264d5d 289 Gene3D G3DSA:3.40.190.10 174 260 1.4E-10 T 28-03-2018 CIG75_RS16395 c38d19900fd182696cf0010c9f264d5d 289 SUPERFAMILY SSF46785 1 86 3.79E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS16395 c38d19900fd182696cf0010c9f264d5d 289 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 3.1E-20 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CIG75_RS16395 c38d19900fd182696cf0010c9f264d5d 289 Gene3D G3DSA:3.40.190.10 94 173 1.1E-7 T 28-03-2018 CIG75_RS16395 c38d19900fd182696cf0010c9f264d5d 289 Pfam PF03466 LysR substrate binding domain 91 287 4.7E-31 T 28-03-2018 IPR005119 LysR, substrate-binding CIG75_RS16395 c38d19900fd182696cf0010c9f264d5d 289 Gene3D G3DSA:1.10.10.10 1 93 1.6E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS04855 8dbd3845bdaa6ee2bef2263be2ba25bc 154 Gene3D G3DSA:2.60.40.10 69 153 7.9E-6 T 28-03-2018 IPR013783 Immunoglobulin-like fold CIG75_RS14955 33e0720046b8bc219f7d418d49e7d997 258 SUPERFAMILY SSF56784 5 254 4.75E-72 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS14955 33e0720046b8bc219f7d418d49e7d997 258 PIRSF PIRSF000915 1 116 2.2E-29 T 28-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA CIG75_RS14955 33e0720046b8bc219f7d418d49e7d997 258 PIRSF PIRSF000915 107 258 3.0E-37 T 28-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA CIG75_RS14955 33e0720046b8bc219f7d418d49e7d997 258 Pfam PF13242 HAD-hyrolase-like 179 253 8.9E-22 T 28-03-2018 CIG75_RS14955 33e0720046b8bc219f7d418d49e7d997 258 TIGRFAM TIGR01457 HAD-SF-IIA-hyp2: HAD hydrolase, TIGR01457 family 6 252 3.0E-91 T 28-03-2018 IPR006354 HAD-superfamily hydrolase, subfamily IIA, hypothetical 1 CIG75_RS14955 33e0720046b8bc219f7d418d49e7d997 258 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 7 229 1.5E-40 T 28-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA CIG75_RS14955 33e0720046b8bc219f7d418d49e7d997 258 Gene3D G3DSA:3.40.50.1000 1 257 5.0E-36 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS14955 33e0720046b8bc219f7d418d49e7d997 258 Pfam PF13344 Haloacid dehalogenase-like hydrolase 7 106 3.2E-27 T 28-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA CIG75_RS20190 dbb4b9be1ec6258c62d6b18359f2825d 125 SMART SM00530 5 61 2.0E-16 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS20190 dbb4b9be1ec6258c62d6b18359f2825d 125 Gene3D G3DSA:1.10.260.40 1 124 1.3E-22 T 28-03-2018 CIG75_RS20190 dbb4b9be1ec6258c62d6b18359f2825d 125 Pfam PF08671 Anti-repressor SinI 87 114 8.9E-8 T 28-03-2018 IPR010981 SinR repressor/SinI anti-repressor, dimerisation domain GO:0006355|GO:0046983 CIG75_RS20190 dbb4b9be1ec6258c62d6b18359f2825d 125 SUPERFAMILY SSF47406 87 120 3.66E-8 T 28-03-2018 IPR010981 SinR repressor/SinI anti-repressor, dimerisation domain GO:0006355|GO:0046983 CIG75_RS20190 dbb4b9be1ec6258c62d6b18359f2825d 125 Pfam PF01381 Helix-turn-helix 6 61 1.6E-14 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS20190 dbb4b9be1ec6258c62d6b18359f2825d 125 SUPERFAMILY SSF47413 2 64 7.32E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CIG75_RS05240 9cfafe0ac7078459a636d0f7fe5be14e 365 SUPERFAMILY SSF48452 57 165 2.53E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS05240 9cfafe0ac7078459a636d0f7fe5be14e 365 Gene3D G3DSA:1.25.40.10 12 104 0.073 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS05240 9cfafe0ac7078459a636d0f7fe5be14e 365 Pfam PF13424 Tetratricopeptide repeat 173 245 1.2E-8 T 28-03-2018 CIG75_RS05240 9cfafe0ac7078459a636d0f7fe5be14e 365 Pfam PF13424 Tetratricopeptide repeat 98 165 3.0E-7 T 28-03-2018 CIG75_RS05240 9cfafe0ac7078459a636d0f7fe5be14e 365 Gene3D G3DSA:1.25.40.10 105 188 3.7E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS05240 9cfafe0ac7078459a636d0f7fe5be14e 365 Gene3D G3DSA:3.30.70.100 212 252 1.1E-7 T 28-03-2018 CIG75_RS05240 9cfafe0ac7078459a636d0f7fe5be14e 365 Gene3D G3DSA:3.30.70.100 189 211 0.019 T 28-03-2018 CIG75_RS05240 9cfafe0ac7078459a636d0f7fe5be14e 365 SUPERFAMILY SSF48452 130 320 2.5E-23 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS05240 9cfafe0ac7078459a636d0f7fe5be14e 365 Gene3D G3DSA:1.10.150.200 253 300 2.5E-5 T 28-03-2018 CIG75_RS05240 9cfafe0ac7078459a636d0f7fe5be14e 365 Gene3D G3DSA:1.25.40.10 301 364 0.22 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS05240 9cfafe0ac7078459a636d0f7fe5be14e 365 SMART SM00028 92 125 270.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS05240 9cfafe0ac7078459a636d0f7fe5be14e 365 SMART SM00028 254 287 17.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS05240 9cfafe0ac7078459a636d0f7fe5be14e 365 SMART SM00028 214 247 34.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS05240 9cfafe0ac7078459a636d0f7fe5be14e 365 SMART SM00028 134 167 0.67 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS05240 9cfafe0ac7078459a636d0f7fe5be14e 365 SMART SM00028 174 207 98.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS04500 0b46e522ce152cfaa13d6fdc156357cd 249 Pfam PF13276 HTH-like domain 9 66 2.4E-18 T 28-03-2018 IPR025948 HTH-like domain CIG75_RS04500 0b46e522ce152cfaa13d6fdc156357cd 249 Pfam PF00665 Integrase core domain 89 202 2.7E-25 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CIG75_RS04500 0b46e522ce152cfaa13d6fdc156357cd 249 Gene3D G3DSA:3.30.420.10 84 249 4.8E-33 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CIG75_RS04500 0b46e522ce152cfaa13d6fdc156357cd 249 SUPERFAMILY SSF53098 82 246 2.91E-36 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CIG75_RS02480 05342530f332019daa8fed1df4421c0f 233 TIGRFAM TIGR02055 APS_reductase: adenylylsulfate reductase, thioredoxin dependent 44 231 2.9E-74 T 28-03-2018 IPR011798 Adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019344|GO:0055114 KEGG: 00920+1.8.4.8 CIG75_RS02480 05342530f332019daa8fed1df4421c0f 233 SUPERFAMILY SSF52402 13 197 1.02E-52 T 28-03-2018 CIG75_RS02480 05342530f332019daa8fed1df4421c0f 233 TIGRFAM TIGR00434 cysH: phosophoadenylyl-sulfate reductase 27 233 6.9E-75 T 28-03-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 CIG75_RS02480 05342530f332019daa8fed1df4421c0f 233 Hamap MF_00063 Phosphoadenosine phosphosulfate reductase [cysH]. 7 233 38.314 T 28-03-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 CIG75_RS02480 05342530f332019daa8fed1df4421c0f 233 Gene3D G3DSA:3.40.50.620 4 233 5.7E-46 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CIG75_RS02480 05342530f332019daa8fed1df4421c0f 233 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 39 208 4.1E-48 T 28-03-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 CIG75_RS02480 05342530f332019daa8fed1df4421c0f 233 PIRSF PIRSF000857 3 233 1.9E-89 T 28-03-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 CIG75_RS02065 5c8bc025bebe339bbcea70386e7970db 144 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 2 141 32.51 T 28-03-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CIG75_RS02065 5c8bc025bebe339bbcea70386e7970db 144 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 2 138 2.3E-53 T 28-03-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CIG75_RS02065 5c8bc025bebe339bbcea70386e7970db 144 Pfam PF07977 FabA-like domain 12 134 2.4E-35 T 28-03-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CIG75_RS02065 5c8bc025bebe339bbcea70386e7970db 144 Gene3D G3DSA:3.10.129.10 2 144 3.4E-53 T 28-03-2018 CIG75_RS02065 5c8bc025bebe339bbcea70386e7970db 144 SUPERFAMILY SSF54637 2 138 2.16E-46 T 28-03-2018 IPR029069 HotDog domain CIG75_RS02670 77604daf4d0c8baba760014508cea088 127 PIRSF PIRSF021774 1 127 7.9E-39 T 28-03-2018 IPR016796 Uncharacterised conserved protein UCP021774 CIG75_RS02670 77604daf4d0c8baba760014508cea088 127 Pfam PF03625 Domain of unknown function DUF302 34 96 3.1E-17 T 28-03-2018 IPR005180 Domain of unknown function DUF302 CIG75_RS02670 77604daf4d0c8baba760014508cea088 127 Gene3D G3DSA:3.30.310.70 1 127 2.0E-36 T 28-03-2018 IPR005180 Domain of unknown function DUF302 CIG75_RS02670 77604daf4d0c8baba760014508cea088 127 SUPERFAMILY SSF103247 1 126 1.22E-35 T 28-03-2018 IPR005180 Domain of unknown function DUF302 CIG75_RS13565 e850d3be67bf56a141443a31a18831d1 546 Gene3D G3DSA:3.40.190.10 175 309 4.1E-34 T 28-03-2018 CIG75_RS13565 e850d3be67bf56a141443a31a18831d1 546 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 88 110 - T 28-03-2018 IPR023765 Solute-binding protein family 5, conserved site CIG75_RS13565 e850d3be67bf56a141443a31a18831d1 546 Gene3D G3DSA:3.90.76.10 64 174 1.5E-34 T 28-03-2018 CIG75_RS13565 e850d3be67bf56a141443a31a18831d1 546 SUPERFAMILY SSF53850 37 543 1.81E-122 T 28-03-2018 CIG75_RS13565 e850d3be67bf56a141443a31a18831d1 546 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 84 465 2.2E-78 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CIG75_RS13565 e850d3be67bf56a141443a31a18831d1 546 Gene3D G3DSA:3.10.105.10 310 513 5.0E-45 T 28-03-2018 CIG75_RS13565 e850d3be67bf56a141443a31a18831d1 546 PIRSF PIRSF002741 2 546 1.6E-104 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CIG75_RS10410 b98311e977d52fe7f13797bcb7103464 2124 Gene3D G3DSA:3.30.300.30 1457 1578 2.9E-36 T 28-03-2018 CIG75_RS10410 b98311e977d52fe7f13797bcb7103464 2124 Gene3D G3DSA:3.30.300.30 399 520 1.0E-40 T 28-03-2018 CIG75_RS10410 b98311e977d52fe7f13797bcb7103464 2124 SUPERFAMILY SSF56801 4 528 7.85E-158 T 28-03-2018 CIG75_RS10410 b98311e977d52fe7f13797bcb7103464 2124 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1599 1614 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS10410 b98311e977d52fe7f13797bcb7103464 2124 SUPERFAMILY SSF52777 1843 2107 8.89E-43 T 28-03-2018 CIG75_RS10410 b98311e977d52fe7f13797bcb7103464 2124 SUPERFAMILY SSF52777 606 775 4.67E-50 T 28-03-2018 CIG75_RS10410 b98311e977d52fe7f13797bcb7103464 2124 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1081 1486 1.1E-125 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS10410 b98311e977d52fe7f13797bcb7103464 2124 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 31 428 3.1E-133 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS10410 b98311e977d52fe7f13797bcb7103464 2124 Gene3D G3DSA:3.40.50.980 1 157 2.0E-48 T 28-03-2018 CIG75_RS10410 b98311e977d52fe7f13797bcb7103464 2124 Gene3D G3DSA:3.40.50.980 1051 1207 3.7E-44 T 28-03-2018 CIG75_RS10410 b98311e977d52fe7f13797bcb7103464 2124 SUPERFAMILY SSF47336 1568 1640 6.81E-20 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10410 b98311e977d52fe7f13797bcb7103464 2124 SUPERFAMILY SSF52777 781 1047 1.45E-70 T 28-03-2018 CIG75_RS10410 b98311e977d52fe7f13797bcb7103464 2124 SUPERFAMILY SSF47336 508 580 9.95E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10410 b98311e977d52fe7f13797bcb7103464 2124 ProSitePatterns PS00012 Phosphopantetheine attachment site. 539 554 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS10410 b98311e977d52fe7f13797bcb7103464 2124 Gene3D G3DSA:2.30.38.10 1372 1452 1.4E-25 T 28-03-2018 CIG75_RS10410 b98311e977d52fe7f13797bcb7103464 2124 Gene3D G3DSA:1.10.1200.10 521 584 5.3E-19 T 28-03-2018 CIG75_RS10410 b98311e977d52fe7f13797bcb7103464 2124 Pfam PF00550 Phosphopantetheine attachment site 517 580 1.5E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10410 b98311e977d52fe7f13797bcb7103464 2124 Pfam PF00550 Phosphopantetheine attachment site 1577 1639 1.7E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10410 b98311e977d52fe7f13797bcb7103464 2124 ProSitePatterns PS00455 Putative AMP-binding domain signature. 152 163 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS10410 b98311e977d52fe7f13797bcb7103464 2124 Gene3D G3DSA:2.30.38.10 314 397 5.8E-23 T 28-03-2018 CIG75_RS10410 b98311e977d52fe7f13797bcb7103464 2124 Pfam PF13193 AMP-binding enzyme C-terminal domain 412 487 1.4E-11 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS10410 b98311e977d52fe7f13797bcb7103464 2124 Pfam PF13193 AMP-binding enzyme C-terminal domain 1470 1547 7.2E-10 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS10410 b98311e977d52fe7f13797bcb7103464 2124 SMART SM00823 Phosphopantetheine attachment site 1575 1644 0.0011 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS10410 b98311e977d52fe7f13797bcb7103464 2124 SMART SM00823 Phosphopantetheine attachment site 515 584 8.5E-4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS10410 b98311e977d52fe7f13797bcb7103464 2124 Gene3D G3DSA:3.30.559.10 1640 1864 2.7E-36 T 28-03-2018 CIG75_RS10410 b98311e977d52fe7f13797bcb7103464 2124 SUPERFAMILY SSF52777 1664 1837 3.78E-36 T 28-03-2018 CIG75_RS10410 b98311e977d52fe7f13797bcb7103464 2124 Gene3D G3DSA:3.40.50.980 158 313 2.3E-35 T 28-03-2018 CIG75_RS10410 b98311e977d52fe7f13797bcb7103464 2124 Gene3D G3DSA:3.40.50.980 1208 1370 2.1E-38 T 28-03-2018 CIG75_RS10410 b98311e977d52fe7f13797bcb7103464 2124 Gene3D G3DSA:1.10.1200.10 1579 1639 2.5E-21 T 28-03-2018 CIG75_RS10410 b98311e977d52fe7f13797bcb7103464 2124 Pfam PF00501 AMP-binding enzyme 11 404 4.7E-103 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS10410 b98311e977d52fe7f13797bcb7103464 2124 Pfam PF00501 AMP-binding enzyme 1060 1462 1.6E-96 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS10410 b98311e977d52fe7f13797bcb7103464 2124 Pfam PF00668 Condensation domain 1659 2117 4.1E-78 T 28-03-2018 IPR001242 Condensation domain CIG75_RS10410 b98311e977d52fe7f13797bcb7103464 2124 Pfam PF00668 Condensation domain 602 1039 4.8E-115 T 28-03-2018 IPR001242 Condensation domain CIG75_RS10410 b98311e977d52fe7f13797bcb7103464 2124 SUPERFAMILY SSF56801 1017 1588 1.96E-157 T 28-03-2018 CIG75_RS10410 b98311e977d52fe7f13797bcb7103464 2124 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1202 1213 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS10410 b98311e977d52fe7f13797bcb7103464 2124 Gene3D G3DSA:3.30.559.10 585 777 3.0E-41 T 28-03-2018 CIG75_RS06365 6c092ff152fadfd6369b7cc48cf8c55d 730 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 566 706 2.5E-26 T 28-03-2018 IPR000160 GGDEF domain CIG75_RS06365 6c092ff152fadfd6369b7cc48cf8c55d 730 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 390 555 7.6E-50 T 28-03-2018 IPR000160 GGDEF domain CIG75_RS06365 6c092ff152fadfd6369b7cc48cf8c55d 730 Gene3D G3DSA:3.30.70.270 393 562 1.2E-54 T 28-03-2018 CIG75_RS06365 6c092ff152fadfd6369b7cc48cf8c55d 730 Gene3D G3DSA:3.30.70.270 563 715 2.7E-30 T 28-03-2018 CIG75_RS06365 6c092ff152fadfd6369b7cc48cf8c55d 730 Pfam PF13185 GAF domain 249 382 3.1E-13 T 28-03-2018 IPR003018 GAF domain GO:0005515 CIG75_RS06365 6c092ff152fadfd6369b7cc48cf8c55d 730 Pfam PF00990 Diguanylate cyclase, GGDEF domain 566 701 3.2E-25 T 28-03-2018 IPR000160 GGDEF domain CIG75_RS06365 6c092ff152fadfd6369b7cc48cf8c55d 730 Pfam PF00990 Diguanylate cyclase, GGDEF domain 396 551 1.3E-42 T 28-03-2018 IPR000160 GGDEF domain CIG75_RS06365 6c092ff152fadfd6369b7cc48cf8c55d 730 SUPERFAMILY SSF55073 400 558 1.18E-44 T 28-03-2018 IPR029787 Nucleotide cyclase CIG75_RS06365 6c092ff152fadfd6369b7cc48cf8c55d 730 Gene3D G3DSA:3.30.450.40 226 392 6.8E-26 T 28-03-2018 IPR029016 GAF domain-like CIG75_RS06365 6c092ff152fadfd6369b7cc48cf8c55d 730 SUPERFAMILY SSF55073 569 701 2.59E-24 T 28-03-2018 IPR029787 Nucleotide cyclase CIG75_RS06365 6c092ff152fadfd6369b7cc48cf8c55d 730 SMART SM00267 383 556 5.9E-54 T 28-03-2018 IPR000160 GGDEF domain CIG75_RS06365 6c092ff152fadfd6369b7cc48cf8c55d 730 SMART SM00267 562 708 2.2E-7 T 28-03-2018 IPR000160 GGDEF domain CIG75_RS06365 6c092ff152fadfd6369b7cc48cf8c55d 730 SUPERFAMILY SSF55781 231 390 1.29E-23 T 28-03-2018 IPR029016 GAF domain-like CIG75_RS06365 6c092ff152fadfd6369b7cc48cf8c55d 730 SMART SM00065 248 391 8.9E-15 T 28-03-2018 IPR003018 GAF domain GO:0005515 CIG75_RS05385 a5d29d793fa0add547a2972a56357f73 193 Gene3D G3DSA:1.10.10.60 4 59 4.1E-20 T 28-03-2018 CIG75_RS05385 a5d29d793fa0add547a2972a56357f73 193 SUPERFAMILY SSF48498 78 190 7.23E-18 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CIG75_RS05385 a5d29d793fa0add547a2972a56357f73 193 Pfam PF08359 YsiA-like protein, C-terminal region 67 178 1.6E-6 T 28-03-2018 IPR013570 Transcription regulator YsiA, C-terminal CIG75_RS05385 a5d29d793fa0add547a2972a56357f73 193 Gene3D G3DSA:1.10.357.10 60 187 8.2E-23 T 28-03-2018 CIG75_RS05385 a5d29d793fa0add547a2972a56357f73 193 SUPERFAMILY SSF46689 5 83 3.14E-21 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CIG75_RS05385 a5d29d793fa0add547a2972a56357f73 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 1.7E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CIG75_RS05385 a5d29d793fa0add547a2972a56357f73 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 1.7E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CIG75_RS05385 a5d29d793fa0add547a2972a56357f73 193 ProSitePatterns PS01081 TetR-type HTH domain signature. 23 53 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CIG75_RS05385 a5d29d793fa0add547a2972a56357f73 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 54 2.2E-19 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CIG75_RS07225 ce7dc24a60413a6f890b1500ff287e02 347 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 20 29 - T 28-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CIG75_RS07225 ce7dc24a60413a6f890b1500ff287e02 347 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 4 341 46.116 T 28-03-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CIG75_RS07225 ce7dc24a60413a6f890b1500ff287e02 347 SUPERFAMILY SSF51726 1 342 1.7E-108 T 28-03-2018 CIG75_RS07225 ce7dc24a60413a6f890b1500ff287e02 347 Gene3D G3DSA:3.20.20.210 1 343 3.6E-96 T 28-03-2018 CIG75_RS07225 ce7dc24a60413a6f890b1500ff287e02 347 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 3 340 2.2E-124 T 28-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CIG75_RS07225 ce7dc24a60413a6f890b1500ff287e02 347 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 137 153 - T 28-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CIG75_RS07225 ce7dc24a60413a6f890b1500ff287e02 347 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 6 339 8.7E-125 T 28-03-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CIG75_RS18050 5fd789bdbbf346030fcbf1a19579d743 248 Gene3D G3DSA:1.10.10.200 2 75 5.2E-20 T 28-03-2018 IPR017856 Integrase, N-terminal zinc-binding domain-like CIG75_RS18050 5fd789bdbbf346030fcbf1a19579d743 248 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 1 238 31.82 T 28-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CIG75_RS18050 5fd789bdbbf346030fcbf1a19579d743 248 Gene3D G3DSA:3.30.70.980 80 174 2.0E-31 T 28-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CIG75_RS18050 5fd789bdbbf346030fcbf1a19579d743 248 SUPERFAMILY SSF75625 3 245 4.58E-86 T 28-03-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CIG75_RS18050 5fd789bdbbf346030fcbf1a19579d743 248 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 2 237 2.5E-87 T 28-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CIG75_RS18050 5fd789bdbbf346030fcbf1a19579d743 248 Pfam PF01709 Transcriptional regulator 3 236 3.2E-87 T 28-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CIG75_RS18050 5fd789bdbbf346030fcbf1a19579d743 248 Gene3D G3DSA:3.30.70.980 175 247 8.3E-11 T 28-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CIG75_RS03925 05f4740678ff34da7a821a317a8053b8 347 Gene3D G3DSA:3.40.50.1820 40 346 2.7E-36 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS03925 05f4740678ff34da7a821a317a8053b8 347 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 94 105 5.9E-8 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CIG75_RS03925 05f4740678ff34da7a821a317a8053b8 347 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 142 156 5.9E-8 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CIG75_RS03925 05f4740678ff34da7a821a317a8053b8 347 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 66 74 5.9E-8 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CIG75_RS03925 05f4740678ff34da7a821a317a8053b8 347 Pfam PF00561 alpha/beta hydrolase fold 64 330 8.5E-18 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CIG75_RS03925 05f4740678ff34da7a821a317a8053b8 347 SUPERFAMILY SSF53474 220 338 3.59E-39 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS03925 05f4740678ff34da7a821a317a8053b8 347 SUPERFAMILY SSF53474 45 172 3.59E-39 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS05015 e38be3a85fe5434ec449ffeb822c10d4 470 SUPERFAMILY SSF52540 275 450 2.66E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS05015 e38be3a85fe5434ec449ffeb822c10d4 470 Gene3D G3DSA:3.30.1890.10 35 161 1.7E-10 T 28-03-2018 CIG75_RS05015 e38be3a85fe5434ec449ffeb822c10d4 470 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 277 445 1.0E-7 T 28-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain CIG75_RS05015 e38be3a85fe5434ec449ffeb822c10d4 470 Gene3D G3DSA:3.40.50.300 271 465 2.2E-26 T 28-03-2018 CIG75_RS05015 e38be3a85fe5434ec449ffeb822c10d4 470 Pfam PF02706 Chain length determinant protein 9 93 9.2E-11 T 28-03-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 CIG75_RS19605 32be9d917e056a5245bf2073c549b989 122 Gene3D G3DSA:4.10.910.10 68 86 4.7E-17 T 28-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CIG75_RS19605 32be9d917e056a5245bf2073c549b989 122 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 115 1.3E-54 T 28-03-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS19605 32be9d917e056a5245bf2073c549b989 122 Gene3D G3DSA:4.10.910.10 87 122 4.7E-28 T 28-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CIG75_RS19605 32be9d917e056a5245bf2073c549b989 122 Pfam PF00416 Ribosomal protein S13/S18 3 109 5.9E-35 T 28-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CIG75_RS19605 32be9d917e056a5245bf2073c549b989 122 ProSitePatterns PS00646 Ribosomal protein S13 signature. 88 101 - T 28-03-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CIG75_RS19605 32be9d917e056a5245bf2073c549b989 122 SUPERFAMILY SSF46946 2 121 1.77E-46 T 28-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CIG75_RS19605 32be9d917e056a5245bf2073c549b989 122 Gene3D G3DSA:1.10.8.50 1 67 2.4E-26 T 28-03-2018 CIG75_RS19605 32be9d917e056a5245bf2073c549b989 122 PIRSF PIRSF002134 1 122 1.5E-43 T 28-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CIG75_RS19605 32be9d917e056a5245bf2073c549b989 122 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 120 29.142 T 28-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CIG75_RS07715 96cdef86f0e90140186f092a38370268 594 SMART SM00465 17 97 9.0E-21 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CIG75_RS07715 96cdef86f0e90140186f092a38370268 594 SUPERFAMILY SSF82771 16 99 3.92E-22 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CIG75_RS07715 96cdef86f0e90140186f092a38370268 594 SUPERFAMILY SSF46600 185 237 1.44E-12 T 28-03-2018 IPR001943 UVR domain GO:0005515 CIG75_RS07715 96cdef86f0e90140186f092a38370268 594 Gene3D G3DSA:1.10.150.20 539 594 8.2E-16 T 28-03-2018 CIG75_RS07715 96cdef86f0e90140186f092a38370268 594 Pfam PF01541 GIY-YIG catalytic domain 18 92 2.2E-9 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CIG75_RS07715 96cdef86f0e90140186f092a38370268 594 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 9 573 7.4E-202 T 28-03-2018 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 CIG75_RS07715 96cdef86f0e90140186f092a38370268 594 SUPERFAMILY SSF47781 505 592 3.18E-21 T 28-03-2018 IPR010994 RuvA domain 2-like CIG75_RS07715 96cdef86f0e90140186f092a38370268 594 Pfam PF02151 UvrB/uvrC motif 199 231 2.5E-5 T 28-03-2018 IPR001943 UVR domain GO:0005515 CIG75_RS07715 96cdef86f0e90140186f092a38370268 594 Hamap MF_00203 UvrABC system protein C [uvrC]. 4 590 28.241 T 28-03-2018 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 CIG75_RS07715 96cdef86f0e90140186f092a38370268 594 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 379 526 1.0E-56 T 28-03-2018 IPR001162 UvrC family homology region CIG75_RS07715 96cdef86f0e90140186f092a38370268 594 Gene3D G3DSA:4.10.860.10 177 237 3.3E-12 T 28-03-2018 IPR001943 UVR domain GO:0005515 CIG75_RS07715 96cdef86f0e90140186f092a38370268 594 Gene3D G3DSA:3.40.1440.10 3 100 2.5E-24 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CIG75_RS07715 96cdef86f0e90140186f092a38370268 594 Pfam PF14520 Helix-hairpin-helix domain 542 588 2.2E-8 T 28-03-2018 CIG75_RS11845 f75de5ec8e1609fb6911576f7b3cb8a2 457 PIRSF PIRSF006060 3 455 2.0E-65 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CIG75_RS11845 f75de5ec8e1609fb6911576f7b3cb8a2 457 Pfam PF00324 Amino acid permease 54 434 1.7E-37 T 28-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CIG75_RS03680 3f5520c17ac6d6d40035f878d151f18d 745 Gene3D G3DSA:3.40.50.300 290 391 2.7E-26 T 28-03-2018 CIG75_RS03680 3f5520c17ac6d6d40035f878d151f18d 745 Pfam PF13361 UvrD-like helicase C-terminal domain 284 624 1.7E-75 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CIG75_RS03680 3f5520c17ac6d6d40035f878d151f18d 745 TIGRFAM TIGR01073 pcrA: ATP-dependent DNA helicase PcrA 10 740 0.0 T 28-03-2018 IPR005751 ATP-dependent DNA helicase PcrA GO:0004003|GO:0005737|GO:0006268 CIG75_RS03680 3f5520c17ac6d6d40035f878d151f18d 745 Pfam PF00580 UvrD/REP helicase N-terminal domain 14 279 8.8E-83 T 28-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 CIG75_RS03680 3f5520c17ac6d6d40035f878d151f18d 745 SUPERFAMILY SSF52540 9 652 2.66E-182 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS03680 3f5520c17ac6d6d40035f878d151f18d 745 Gene3D G3DSA:3.40.50.300 7 157 1.7E-30 T 28-03-2018 CIG75_RS03680 3f5520c17ac6d6d40035f878d151f18d 745 Gene3D G3DSA:3.40.50.300 158 289 4.0E-34 T 28-03-2018 CIG75_RS03680 3f5520c17ac6d6d40035f878d151f18d 745 Gene3D G3DSA:3.40.50.300 448 675 1.3E-48 T 28-03-2018 CIG75_RS00690 c4e521c317787e2f78f61cdb005cdd4c 732 Gene3D G3DSA:3.40.50.300 11 430 3.0E-21 T 28-03-2018 CIG75_RS00690 c4e521c317787e2f78f61cdb005cdd4c 732 SUPERFAMILY SSF52540 12 173 1.39E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS00690 c4e521c317787e2f78f61cdb005cdd4c 732 SUPERFAMILY SSF52540 309 429 1.39E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS00690 c4e521c317787e2f78f61cdb005cdd4c 732 Pfam PF13175 AAA ATPase domain 12 412 3.0E-25 T 28-03-2018 CIG75_RS02475 ac60a38ec1005b7d12b36a051800d1be 299 Gene3D G3DSA:3.40.800.10 1 298 1.1E-97 T 28-03-2018 CIG75_RS02475 ac60a38ec1005b7d12b36a051800d1be 299 ProSitePatterns PS01053 Arginase family signature. 224 245 - T 28-03-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 CIG75_RS02475 ac60a38ec1005b7d12b36a051800d1be 299 Pfam PF00491 Arginase family 4 294 1.0E-84 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 CIG75_RS02475 ac60a38ec1005b7d12b36a051800d1be 299 PIRSF PIRSF036979 1 298 1.4E-41 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 CIG75_RS02475 ac60a38ec1005b7d12b36a051800d1be 299 TIGRFAM TIGR01229 rocF_arginase: arginase 6 299 3.0E-101 T 28-03-2018 IPR014033 Arginase GO:0004053|GO:0006525|GO:0046872 KEGG: 00220+3.5.3.1|KEGG: 00330+3.5.3.1|MetaCyc: PWY-31|MetaCyc: PWY-4984|MetaCyc: PWY-6305|MetaCyc: PWY-6922|Reactome: R-HSA-70635 CIG75_RS02475 ac60a38ec1005b7d12b36a051800d1be 299 PRINTS PR00116 Arginase signature 172 190 5.5E-44 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 CIG75_RS02475 ac60a38ec1005b7d12b36a051800d1be 299 PRINTS PR00116 Arginase signature 256 270 5.5E-44 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 CIG75_RS02475 ac60a38ec1005b7d12b36a051800d1be 299 PRINTS PR00116 Arginase signature 221 250 5.5E-44 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 CIG75_RS02475 ac60a38ec1005b7d12b36a051800d1be 299 PRINTS PR00116 Arginase signature 95 110 5.5E-44 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 CIG75_RS02475 ac60a38ec1005b7d12b36a051800d1be 299 PRINTS PR00116 Arginase signature 118 145 5.5E-44 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 CIG75_RS02475 ac60a38ec1005b7d12b36a051800d1be 299 SUPERFAMILY SSF52768 4 296 1.66E-98 T 28-03-2018 CIG75_RS14490 3207d0ce1d8f2dac53fa8794ed884e3a 195 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 74 90 2.8E-5 T 28-03-2018 CIG75_RS14490 3207d0ce1d8f2dac53fa8794ed884e3a 195 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 44 58 2.8E-5 T 28-03-2018 CIG75_RS14490 3207d0ce1d8f2dac53fa8794ed884e3a 195 SUPERFAMILY SSF52317 1 187 8.77E-57 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CIG75_RS14490 3207d0ce1d8f2dac53fa8794ed884e3a 195 Pfam PF00117 Glutamine amidotransferase class-I 4 185 2.0E-56 T 28-03-2018 IPR017926 Glutamine amidotransferase CIG75_RS14490 3207d0ce1d8f2dac53fa8794ed884e3a 195 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 1 187 1.8E-85 T 28-03-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CIG75_RS14490 3207d0ce1d8f2dac53fa8794ed884e3a 195 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 1.2E-13 T 28-03-2018 CIG75_RS14490 3207d0ce1d8f2dac53fa8794ed884e3a 195 PRINTS PR00096 Glutamine amidotransferase superfamily signature 164 177 1.2E-13 T 28-03-2018 CIG75_RS14490 3207d0ce1d8f2dac53fa8794ed884e3a 195 PRINTS PR00096 Glutamine amidotransferase superfamily signature 47 56 1.2E-13 T 28-03-2018 CIG75_RS14490 3207d0ce1d8f2dac53fa8794ed884e3a 195 PRINTS PR00097 Anthranilate synthase component II signature 99 107 1.1E-35 T 28-03-2018 CIG75_RS14490 3207d0ce1d8f2dac53fa8794ed884e3a 195 PRINTS PR00097 Anthranilate synthase component II signature 164 177 1.1E-35 T 28-03-2018 CIG75_RS14490 3207d0ce1d8f2dac53fa8794ed884e3a 195 PRINTS PR00097 Anthranilate synthase component II signature 2 16 1.1E-35 T 28-03-2018 CIG75_RS14490 3207d0ce1d8f2dac53fa8794ed884e3a 195 PRINTS PR00097 Anthranilate synthase component II signature 119 131 1.1E-35 T 28-03-2018 CIG75_RS14490 3207d0ce1d8f2dac53fa8794ed884e3a 195 PRINTS PR00097 Anthranilate synthase component II signature 47 56 1.1E-35 T 28-03-2018 CIG75_RS14490 3207d0ce1d8f2dac53fa8794ed884e3a 195 PRINTS PR00097 Anthranilate synthase component II signature 74 85 1.1E-35 T 28-03-2018 CIG75_RS14490 3207d0ce1d8f2dac53fa8794ed884e3a 195 Gene3D G3DSA:3.40.50.880 1 188 1.1E-57 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CIG75_RS00220 8d1aca8386aba84a55fa55e716f7b075 455 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 6 453 34.511 T 28-03-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CIG75_RS00220 8d1aca8386aba84a55fa55e716f7b075 455 Pfam PF00308 Bacterial dnaA protein 118 334 1.6E-106 T 28-03-2018 IPR013317 Chromosomal replication initiator protein DnaA CIG75_RS00220 8d1aca8386aba84a55fa55e716f7b075 455 SUPERFAMILY SSF48295 349 452 8.11E-37 T 28-03-2018 IPR010921 Trp repressor/replication initiator GO:0043565 CIG75_RS00220 8d1aca8386aba84a55fa55e716f7b075 455 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 365 431 1.5E-29 T 28-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CIG75_RS00220 8d1aca8386aba84a55fa55e716f7b075 455 Gene3D G3DSA:1.10.8.60 284 355 3.7E-28 T 28-03-2018 CIG75_RS00220 8d1aca8386aba84a55fa55e716f7b075 455 Gene3D G3DSA:3.40.50.300 115 282 1.1E-22 T 28-03-2018 CIG75_RS00220 8d1aca8386aba84a55fa55e716f7b075 455 SMART SM00760 362 431 2.2E-40 T 28-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CIG75_RS00220 8d1aca8386aba84a55fa55e716f7b075 455 Gene3D G3DSA:1.10.1750.10 356 453 1.1E-34 T 28-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CIG75_RS00220 8d1aca8386aba84a55fa55e716f7b075 455 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 9 452 2.7E-184 T 28-03-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CIG75_RS00220 8d1aca8386aba84a55fa55e716f7b075 455 SMART SM00382 150 278 2.3E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS00220 8d1aca8386aba84a55fa55e716f7b075 455 Pfam PF11638 DnaA N-terminal domain 8 68 1.4E-18 T 28-03-2018 IPR024633 DnaA N-terminal domain CIG75_RS00220 8d1aca8386aba84a55fa55e716f7b075 455 ProSitePatterns PS01008 DnaA protein signature. 412 431 - T 28-03-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CIG75_RS00220 8d1aca8386aba84a55fa55e716f7b075 455 SUPERFAMILY SSF52540 118 330 1.27E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS00220 8d1aca8386aba84a55fa55e716f7b075 455 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 215 229 6.8E-54 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CIG75_RS00220 8d1aca8386aba84a55fa55e716f7b075 455 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 151 171 6.8E-54 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CIG75_RS00220 8d1aca8386aba84a55fa55e716f7b075 455 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 183 197 6.8E-54 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CIG75_RS00220 8d1aca8386aba84a55fa55e716f7b075 455 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 249 276 6.8E-54 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CIG75_RS00220 8d1aca8386aba84a55fa55e716f7b075 455 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 412 431 6.8E-54 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CIG75_RS09330 73ca287d76720c6bc15dfcafb357e9e2 228 SUPERFAMILY SSF53187 40 226 1.26E-41 T 28-03-2018 CIG75_RS09330 73ca287d76720c6bc15dfcafb357e9e2 228 SMART SM00646 112 222 1.9E-19 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CIG75_RS09330 73ca287d76720c6bc15dfcafb357e9e2 228 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 41 222 2.4E-38 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CIG75_RS09330 73ca287d76720c6bc15dfcafb357e9e2 228 Gene3D G3DSA:3.40.630.40 38 228 3.4E-45 T 28-03-2018 CIG75_RS13470 d0a399ded3161a45a9f1bc4457b0c49c 247 Pfam PF05949 Bacterial protein of unknown function (DUF881) 100 241 1.9E-35 T 28-03-2018 IPR010273 Protein of unknown function DUF881 CIG75_RS14770 abb972ca0bace439382cdcbbfe4bd057 58 Gene3D G3DSA:1.20.5.1150 16 52 1.3E-16 T 28-03-2018 CIG75_RS14770 abb972ca0bace439382cdcbbfe4bd057 58 ProSitePatterns PS01181 Ribosomal protein S21 signature. 13 25 - T 28-03-2018 IPR018278 Ribosomal protein S21, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS14770 abb972ca0bace439382cdcbbfe4bd057 58 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 1 57 19.468 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS14770 abb972ca0bace439382cdcbbfe4bd057 58 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 16 43 1.0E-6 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS14770 abb972ca0bace439382cdcbbfe4bd057 58 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 3 56 1.0E-21 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS14770 abb972ca0bace439382cdcbbfe4bd057 58 PRINTS PR00976 Ribosomal protein S21 family signature 37 47 5.3E-15 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS14770 abb972ca0bace439382cdcbbfe4bd057 58 PRINTS PR00976 Ribosomal protein S21 family signature 5 13 5.3E-15 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS14770 abb972ca0bace439382cdcbbfe4bd057 58 PRINTS PR00976 Ribosomal protein S21 family signature 25 35 5.3E-15 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS14770 abb972ca0bace439382cdcbbfe4bd057 58 PRINTS PR00976 Ribosomal protein S21 family signature 13 22 5.3E-15 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS14770 abb972ca0bace439382cdcbbfe4bd057 58 Pfam PF01165 Ribosomal protein S21 3 56 7.0E-21 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS11800 fdcf8d77b1b73c7b2a7c78435416488f 800 SUPERFAMILY SSF50447 702 797 5.41E-32 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CIG75_RS11800 fdcf8d77b1b73c7b2a7c78435416488f 800 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 3 799 17.672 T 28-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 CIG75_RS11800 fdcf8d77b1b73c7b2a7c78435416488f 800 SUPERFAMILY SSF50447 474 556 1.96E-28 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CIG75_RS11800 fdcf8d77b1b73c7b2a7c78435416488f 800 Pfam PF00009 Elongation factor Tu GTP binding domain 304 461 6.4E-36 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CIG75_RS11800 fdcf8d77b1b73c7b2a7c78435416488f 800 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 2 50 3.9E-9 T 28-03-2018 IPR006847 Translation initiation factor IF-2, N-terminal CIG75_RS11800 fdcf8d77b1b73c7b2a7c78435416488f 800 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 226 275 1.2E-11 T 28-03-2018 IPR006847 Translation initiation factor IF-2, N-terminal CIG75_RS11800 fdcf8d77b1b73c7b2a7c78435416488f 800 Gene3D G3DSA:2.40.30.10 702 800 2.2E-29 T 28-03-2018 CIG75_RS11800 fdcf8d77b1b73c7b2a7c78435416488f 800 Pfam PF11987 Translation-initiation factor 2 587 691 3.6E-38 T 28-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 CIG75_RS11800 fdcf8d77b1b73c7b2a7c78435416488f 800 SUPERFAMILY SSF52156 581 708 1.44E-38 T 28-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 CIG75_RS11800 fdcf8d77b1b73c7b2a7c78435416488f 800 Gene3D G3DSA:3.40.50.10050 605 680 1.4E-28 T 28-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 CIG75_RS11800 fdcf8d77b1b73c7b2a7c78435416488f 800 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 220 798 4.3E-267 T 28-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 CIG75_RS11800 fdcf8d77b1b73c7b2a7c78435416488f 800 SUPERFAMILY SSF52540 292 473 1.16E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS11800 fdcf8d77b1b73c7b2a7c78435416488f 800 Gene3D G3DSA:3.30.56.50 4 46 1.6E-8 T 28-03-2018 CIG75_RS11800 fdcf8d77b1b73c7b2a7c78435416488f 800 Gene3D G3DSA:3.30.56.50 227 267 1.1E-7 T 28-03-2018 CIG75_RS11800 fdcf8d77b1b73c7b2a7c78435416488f 800 Gene3D G3DSA:2.40.30.10 476 604 3.3E-35 T 28-03-2018 CIG75_RS11800 fdcf8d77b1b73c7b2a7c78435416488f 800 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 303 460 4.0E-40 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CIG75_RS11800 fdcf8d77b1b73c7b2a7c78435416488f 800 Gene3D G3DSA:3.40.50.300 296 475 8.9E-42 T 28-03-2018 CIG75_RS02555 743d7535cd433b5ab7dfbfc39fedeac2 355 Pfam PF00301 Rubredoxin 4 42 1.1E-6 T 28-03-2018 IPR024935 Rubredoxin domain GO:0005506 CIG75_RS02555 743d7535cd433b5ab7dfbfc39fedeac2 355 Pfam PF13649 Methyltransferase domain 89 188 6.8E-14 T 28-03-2018 CIG75_RS02555 743d7535cd433b5ab7dfbfc39fedeac2 355 Gene3D G3DSA:3.40.50.150 38 290 7.6E-23 T 28-03-2018 CIG75_RS02555 743d7535cd433b5ab7dfbfc39fedeac2 355 SUPERFAMILY SSF57802 1 51 8.16E-8 T 28-03-2018 CIG75_RS02555 743d7535cd433b5ab7dfbfc39fedeac2 355 Gene3D G3DSA:2.20.28.10 1 37 2.0E-8 T 28-03-2018 CIG75_RS02555 743d7535cd433b5ab7dfbfc39fedeac2 355 SUPERFAMILY SSF53335 60 285 9.11E-26 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CIG75_RS10205 952c19c938dc66f8820cd1d7492c047a 552 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 8 333 2.1E-95 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CIG75_RS10205 952c19c938dc66f8820cd1d7492c047a 552 SUPERFAMILY SSF51445 7 372 1.37E-97 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CIG75_RS10205 952c19c938dc66f8820cd1d7492c047a 552 Gene3D G3DSA:3.20.20.300 13 366 1.2E-96 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CIG75_RS10205 952c19c938dc66f8820cd1d7492c047a 552 SUPERFAMILY SSF52279 376 537 1.7E-5 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CIG75_RS10205 952c19c938dc66f8820cd1d7492c047a 552 Gene3D G3DSA:3.40.50.1700 367 539 1.5E-17 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CIG75_RS10205 952c19c938dc66f8820cd1d7492c047a 552 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 376 538 7.4E-9 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CIG75_RS01935 656eedfe0c1b709d2347b6141c1e3445 502 Gene3D G3DSA:3.40.50.300 83 364 4.1E-121 T 28-03-2018 CIG75_RS01935 656eedfe0c1b709d2347b6141c1e3445 502 SUPERFAMILY SSF50615 10 94 2.88E-30 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CIG75_RS01935 656eedfe0c1b709d2347b6141c1e3445 502 Gene3D G3DSA:2.40.30.20 3 82 3.9E-38 T 28-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CIG75_RS01935 656eedfe0c1b709d2347b6141c1e3445 502 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 149 364 1.1E-72 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CIG75_RS01935 656eedfe0c1b709d2347b6141c1e3445 502 Gene3D G3DSA:1.20.150.20 373 500 5.7E-54 T 28-03-2018 CIG75_RS01935 656eedfe0c1b709d2347b6141c1e3445 502 SUPERFAMILY SSF47917 372 500 8.11E-49 T 28-03-2018 CIG75_RS01935 656eedfe0c1b709d2347b6141c1e3445 502 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 355 364 - T 28-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CIG75_RS01935 656eedfe0c1b709d2347b6141c1e3445 502 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 1 501 52.392 T 28-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CIG75_RS01935 656eedfe0c1b709d2347b6141c1e3445 502 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 28 92 7.5E-18 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CIG75_RS01935 656eedfe0c1b709d2347b6141c1e3445 502 PIRSF PIRSF039088 1 502 3.6E-260 T 28-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CIG75_RS01935 656eedfe0c1b709d2347b6141c1e3445 502 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 3 501 7.5E-259 T 28-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CIG75_RS01935 656eedfe0c1b709d2347b6141c1e3445 502 SUPERFAMILY SSF52540 96 370 2.42E-98 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS01935 656eedfe0c1b709d2347b6141c1e3445 502 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 371 496 7.0E-51 T 28-03-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CIG75_RS01250 c364e5d29ec437b44140e0885aedef0d 237 Pfam PF01048 Phosphorylase superfamily 16 222 3.4E-40 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CIG75_RS01250 c364e5d29ec437b44140e0885aedef0d 237 Gene3D G3DSA:3.40.50.1580 8 235 2.0E-54 T 28-03-2018 CIG75_RS01250 c364e5d29ec437b44140e0885aedef0d 237 TIGRFAM TIGR00107 deoD: purine nucleoside phosphorylase 4 232 2.4E-108 T 28-03-2018 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 CIG75_RS01250 c364e5d29ec437b44140e0885aedef0d 237 SUPERFAMILY SSF53167 1 232 1.23E-92 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CIG75_RS01250 c364e5d29ec437b44140e0885aedef0d 237 Hamap MF_01627 Purine nucleoside phosphorylase DeoD-type [deoD]. 1 234 47.809 T 28-03-2018 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 CIG75_RS01250 c364e5d29ec437b44140e0885aedef0d 237 ProSitePatterns PS01232 Purine and other phosphorylases family 1 signature. 61 76 - T 28-03-2018 IPR018016 Nucleoside phosphorylase, conserved site GO:0016763 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-73614|Reactome: R-HSA-73621 CIG75_RS00855 c67777bed78c134f5ddce6c35057c8a2 311 TIGRFAM TIGR02320 PEP_mutase: phosphoenolpyruvate mutase 7 279 1.3E-97 T 28-03-2018 IPR012698 Phosphoenolpyruvate phosphomutase, core GO:0050188 KEGG: 00440+5.4.2.9|MetaCyc: PWY-5757|MetaCyc: PWY-6322|MetaCyc: PWY-6682|MetaCyc: PWY-6839|MetaCyc: PWY-7419|MetaCyc: PWY-7510|MetaCyc: PWY-7769 CIG75_RS00855 c67777bed78c134f5ddce6c35057c8a2 311 Pfam PF13714 Phosphoenolpyruvate phosphomutase 7 249 6.8E-65 T 28-03-2018 CIG75_RS00855 c67777bed78c134f5ddce6c35057c8a2 311 Gene3D G3DSA:3.20.20.60 2 307 2.1E-76 T 28-03-2018 CIG75_RS00855 c67777bed78c134f5ddce6c35057c8a2 311 SUPERFAMILY SSF51621 4 288 1.88E-77 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CIG75_RS11710 dad2e97b30e58bdec3d75cbd814af0d3 555 Hamap MF_01491 Ribonuclease J [rnj]. 3 555 47.558 T 28-03-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 CIG75_RS11710 dad2e97b30e58bdec3d75cbd814af0d3 555 PIRSF PIRSF004803 1 555 2.7E-244 T 28-03-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 CIG75_RS11710 dad2e97b30e58bdec3d75cbd814af0d3 555 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 9 553 5.6E-201 T 28-03-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 CIG75_RS11710 dad2e97b30e58bdec3d75cbd814af0d3 555 SMART SM00849 20 215 4.3E-23 T 28-03-2018 IPR001279 Metallo-beta-lactamase CIG75_RS11710 dad2e97b30e58bdec3d75cbd814af0d3 555 Pfam PF00753 Metallo-beta-lactamase superfamily 19 175 3.1E-13 T 28-03-2018 IPR001279 Metallo-beta-lactamase CIG75_RS11710 dad2e97b30e58bdec3d75cbd814af0d3 555 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 355 408 3.9E-12 T 28-03-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain CIG75_RS11710 dad2e97b30e58bdec3d75cbd814af0d3 555 SUPERFAMILY SSF56281 9 424 6.29E-97 T 28-03-2018 IPR001279 Metallo-beta-lactamase CIG75_RS11710 dad2e97b30e58bdec3d75cbd814af0d3 555 ProSitePatterns PS01292 Uncharacterized protein family UPF0036 signature. 364 392 - T 28-03-2018 IPR001587 Ribonuclease J, conserved site CIG75_RS11710 dad2e97b30e58bdec3d75cbd814af0d3 555 Gene3D G3DSA:3.60.15.10 2 448 1.8E-63 T 28-03-2018 IPR001279 Metallo-beta-lactamase CIG75_RS04480 764cdc8f302e2d3d3ddf26dacb088f05 105 Gene3D G3DSA:1.10.287.1080 1 104 1.1E-23 T 28-03-2018 CIG75_RS04480 764cdc8f302e2d3d3ddf26dacb088f05 105 PIRSF PIRSF029826 1 105 4.0E-34 T 28-03-2018 IPR025984 dCTP pyrophosphatase 1 GO:0009143|GO:0047429 KEGG: 00240+3.6.1.12|Reactome: R-HSA-499943 CIG75_RS04480 764cdc8f302e2d3d3ddf26dacb088f05 105 SUPERFAMILY SSF101386 6 100 1.4E-27 T 28-03-2018 CIG75_RS04480 764cdc8f302e2d3d3ddf26dacb088f05 105 Pfam PF12643 MazG-like family 26 101 5.2E-13 T 28-03-2018 IPR025984 dCTP pyrophosphatase 1 GO:0009143|GO:0047429 KEGG: 00240+3.6.1.12|Reactome: R-HSA-499943 CIG75_RS13020 d650a423487ee969ab1d4a6e53130833 255 Pfam PF00970 Oxidoreductase FAD-binding domain 5 94 1.1E-7 T 28-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CIG75_RS13020 d650a423487ee969ab1d4a6e53130833 255 Gene3D G3DSA:2.40.30.10 1 85 7.9E-14 T 28-03-2018 CIG75_RS13020 d650a423487ee969ab1d4a6e53130833 255 Gene3D G3DSA:3.40.50.80 86 204 6.9E-15 T 28-03-2018 CIG75_RS13020 d650a423487ee969ab1d4a6e53130833 255 PIRSF PIRSF006816 1 255 5.9E-66 T 28-03-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 CIG75_RS13020 d650a423487ee969ab1d4a6e53130833 255 SUPERFAMILY SSF52343 91 254 2.36E-34 T 28-03-2018 CIG75_RS13020 d650a423487ee969ab1d4a6e53130833 255 Pfam PF00175 Oxidoreductase NAD-binding domain 107 198 1.3E-6 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CIG75_RS13020 d650a423487ee969ab1d4a6e53130833 255 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 212 253 3.1E-14 T 28-03-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain CIG75_RS13020 d650a423487ee969ab1d4a6e53130833 255 Hamap MF_01211 Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit [pyrK]. 1 255 35.933 T 28-03-2018 IPR023455 Dihydroorotate dehydrogenase electron transfer subunit CIG75_RS13020 d650a423487ee969ab1d4a6e53130833 255 Gene3D G3DSA:2.10.240.10 212 254 1.1E-15 T 28-03-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain CIG75_RS13020 d650a423487ee969ab1d4a6e53130833 255 PRINTS PR00409 Phthalate dioxygenase reductase family signature 106 125 3.6E-5 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CIG75_RS13020 d650a423487ee969ab1d4a6e53130833 255 PRINTS PR00409 Phthalate dioxygenase reductase family signature 184 192 3.6E-5 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CIG75_RS13020 d650a423487ee969ab1d4a6e53130833 255 SUPERFAMILY SSF63380 3 96 4.48E-21 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CIG75_RS04215 1a47a228e65a8ca9d2f37d154a3be67a 142 Pfam PF07552 Spore Coat Protein X and V domain 21 77 6.4E-20 T 28-03-2018 IPR011428 Spore coat protein X/V GO:0030435|GO:0031160 CIG75_RS04215 1a47a228e65a8ca9d2f37d154a3be67a 142 Pfam PF07552 Spore Coat Protein X and V domain 84 141 2.2E-19 T 28-03-2018 IPR011428 Spore coat protein X/V GO:0030435|GO:0031160 CIG75_RS02250 973215e9e5ab6056bdb36c630893a6b3 299 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 19 297 3.5E-80 T 28-03-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 CIG75_RS02250 973215e9e5ab6056bdb36c630893a6b3 299 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 99 297 7.1E-32 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CIG75_RS02250 973215e9e5ab6056bdb36c630893a6b3 299 Gene3D G3DSA:1.10.3720.10 10 293 1.6E-40 T 28-03-2018 CIG75_RS02250 973215e9e5ab6056bdb36c630893a6b3 299 SUPERFAMILY SSF161098 19 292 2.43E-43 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CIG75_RS05230 926e61d44b03f5bdffbf7296b703c3e4 316 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 217 233 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CIG75_RS05230 926e61d44b03f5bdffbf7296b703c3e4 316 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 104 278 2.8E-60 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CIG75_RS05230 926e61d44b03f5bdffbf7296b703c3e4 316 SUPERFAMILY SSF51735 98 278 2.25E-55 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS05230 926e61d44b03f5bdffbf7296b703c3e4 316 SUPERFAMILY SSF52283 3 129 2.04E-15 T 28-03-2018 CIG75_RS05230 926e61d44b03f5bdffbf7296b703c3e4 316 Gene3D G3DSA:3.40.50.720 1 109 1.0E-23 T 28-03-2018 CIG75_RS05230 926e61d44b03f5bdffbf7296b703c3e4 316 Gene3D G3DSA:3.40.50.720 110 279 1.2E-56 T 28-03-2018 CIG75_RS05230 926e61d44b03f5bdffbf7296b703c3e4 316 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 4 315 8.0E-11 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CIG75_RS07465 46b5d8182be7a20d47c37caba5cd63dd 160 Gene3D G3DSA:3.90.80.10 1 160 1.9E-55 T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 CIG75_RS07465 46b5d8182be7a20d47c37caba5cd63dd 160 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 3 159 34.341 T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 CIG75_RS07465 46b5d8182be7a20d47c37caba5cd63dd 160 Pfam PF00719 Inorganic pyrophosphatase 8 158 1.3E-54 T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 CIG75_RS07465 46b5d8182be7a20d47c37caba5cd63dd 160 SUPERFAMILY SSF50324 4 159 6.54E-60 T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 CIG75_RS07465 46b5d8182be7a20d47c37caba5cd63dd 160 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 54 60 - T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 CIG75_RS08290 6624fd4dbd09d2f0496b46651acd11bd 91 ProDom PD064940 YQHV TRANSMEMBRANE MEMBRANE BH2798 7 90 9.0E-16 T 28-03-2018 IPR020390 Uncharacterised protein family YqhV CIG75_RS08290 6624fd4dbd09d2f0496b46651acd11bd 91 Pfam PF10942 Protein of unknown function (DUF2619) 17 85 8.6E-28 T 28-03-2018 IPR020390 Uncharacterised protein family YqhV CIG75_RS12380 ccfa5b2ed66af2c29daaddd58158f8d7 183 SUPERFAMILY SSF54637 74 180 1.73E-24 T 28-03-2018 IPR029069 HotDog domain CIG75_RS12380 ccfa5b2ed66af2c29daaddd58158f8d7 183 PIRSF PIRSF037733 1 183 7.2E-80 T 28-03-2018 IPR017275 Transcription factor FapR GO:0003700|GO:0045717|GO:0045892 CIG75_RS12380 ccfa5b2ed66af2c29daaddd58158f8d7 183 Gene3D G3DSA:3.10.129.10 61 183 1.8E-19 T 28-03-2018 CIG75_RS12380 ccfa5b2ed66af2c29daaddd58158f8d7 183 Gene3D G3DSA:1.10.10.10 2 60 2.3E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS12380 ccfa5b2ed66af2c29daaddd58158f8d7 183 Pfam PF03061 Thioesterase superfamily 116 167 5.1E-5 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CIG75_RS13285 b7b0124d77e305d51efebf642344c3b1 168 Pfam PF00583 Acetyltransferase (GNAT) family 46 137 2.4E-14 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CIG75_RS13285 b7b0124d77e305d51efebf642344c3b1 168 SUPERFAMILY SSF55729 14 167 6.55E-29 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CIG75_RS13285 b7b0124d77e305d51efebf642344c3b1 168 Gene3D G3DSA:3.40.630.30 3 168 1.9E-30 T 28-03-2018 CIG75_RS12120 0937e57d51d44abbe8c216c352b2be7a 300 SUPERFAMILY SSF52210 123 288 1.26E-57 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CIG75_RS12120 0937e57d51d44abbe8c216c352b2be7a 300 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 288 43.366 T 28-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CIG75_RS12120 0937e57d51d44abbe8c216c352b2be7a 300 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 152 181 - T 28-03-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site CIG75_RS12120 0937e57d51d44abbe8c216c352b2be7a 300 PIRSF PIRSF001553 1 291 3.4E-129 T 28-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CIG75_RS12120 0937e57d51d44abbe8c216c352b2be7a 300 Pfam PF00549 CoA-ligase 151 270 3.9E-19 T 28-03-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CIG75_RS12120 0937e57d51d44abbe8c216c352b2be7a 300 PRINTS PR01798 Succinyl-CoA synthase signature 82 99 1.5E-41 T 28-03-2018 CIG75_RS12120 0937e57d51d44abbe8c216c352b2be7a 300 PRINTS PR01798 Succinyl-CoA synthase signature 177 195 1.5E-41 T 28-03-2018 CIG75_RS12120 0937e57d51d44abbe8c216c352b2be7a 300 PRINTS PR01798 Succinyl-CoA synthase signature 208 221 1.5E-41 T 28-03-2018 CIG75_RS12120 0937e57d51d44abbe8c216c352b2be7a 300 PRINTS PR01798 Succinyl-CoA synthase signature 240 257 1.5E-41 T 28-03-2018 CIG75_RS12120 0937e57d51d44abbe8c216c352b2be7a 300 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 236 249 - T 28-03-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site CIG75_RS12120 0937e57d51d44abbe8c216c352b2be7a 300 Pfam PF02629 CoA binding domain 6 99 2.9E-29 T 28-03-2018 IPR003781 CoA-binding GO:0048037 CIG75_RS12120 0937e57d51d44abbe8c216c352b2be7a 300 SUPERFAMILY SSF51735 1 122 3.01E-42 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS12120 0937e57d51d44abbe8c216c352b2be7a 300 Gene3D G3DSA:3.40.50.261 120 300 8.1E-58 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CIG75_RS12120 0937e57d51d44abbe8c216c352b2be7a 300 Gene3D G3DSA:3.40.50.720 1 119 1.1E-42 T 28-03-2018 CIG75_RS12120 0937e57d51d44abbe8c216c352b2be7a 300 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 3 288 5.7E-144 T 28-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CIG75_RS12120 0937e57d51d44abbe8c216c352b2be7a 300 SMART SM00881 4 100 6.0E-32 T 28-03-2018 IPR003781 CoA-binding GO:0048037 CIG75_RS07395 a5cc2e1643a222a610b633231298dbaf 431 Gene3D G3DSA:3.90.1150.10 260 424 3.0E-54 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CIG75_RS07395 a5cc2e1643a222a610b633231298dbaf 431 Pfam PF00202 Aminotransferase class-III 13 420 2.1E-126 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CIG75_RS07395 a5cc2e1643a222a610b633231298dbaf 431 SUPERFAMILY SSF53383 14 420 4.95E-139 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CIG75_RS07395 a5cc2e1643a222a610b633231298dbaf 431 TIGRFAM TIGR00700 GABAtrnsam: 4-aminobutyrate transaminase 15 420 6.1E-167 T 28-03-2018 IPR004632 4-aminobutyrate aminotransferase, bacterial GO:0003867|GO:0009448 CIG75_RS07395 a5cc2e1643a222a610b633231298dbaf 431 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 235 272 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CIG75_RS07395 a5cc2e1643a222a610b633231298dbaf 431 Gene3D G3DSA:3.90.1150.10 190 259 1.8E-4 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CIG75_RS07395 a5cc2e1643a222a610b633231298dbaf 431 PIRSF PIRSF000521 114 423 2.0E-40 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CIG75_RS07395 a5cc2e1643a222a610b633231298dbaf 431 PIRSF PIRSF000521 8 121 8.6E-5 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CIG75_RS07395 a5cc2e1643a222a610b633231298dbaf 431 Gene3D G3DSA:3.90.1150.10 4 189 1.1E-37 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CIG75_RS13220 4d4b5146398d120772f3f1e09648f346 324 TIGRFAM TIGR02854 spore_II_GA: sigma-E processing peptidase SpoIIGA 7 306 1.6E-76 T 28-03-2018 IPR005081 Sigma-E processing peptidase SpoIIGA GO:0004190|GO:0006508|GO:0030436 CIG75_RS13220 4d4b5146398d120772f3f1e09648f346 324 PIRSF PIRSF018571 7 309 3.4E-83 T 28-03-2018 IPR005081 Sigma-E processing peptidase SpoIIGA GO:0004190|GO:0006508|GO:0030436 CIG75_RS13220 4d4b5146398d120772f3f1e09648f346 324 Pfam PF03419 Sporulation factor SpoIIGA 8 306 5.9E-81 T 28-03-2018 IPR005081 Sigma-E processing peptidase SpoIIGA GO:0004190|GO:0006508|GO:0030436 CIG75_RS04775 914f3086b128d9011bc926fbb7e61f39 356 TIGRFAM TIGR00716 rnhC: ribonuclease HIII 88 350 1.3E-57 T 28-03-2018 IPR004641 Ribonuclease HIII GO:0004523|GO:0005737|GO:0016070 CIG75_RS04775 914f3086b128d9011bc926fbb7e61f39 356 Pfam PF01351 Ribonuclease HII 146 351 1.8E-30 T 28-03-2018 IPR024567 Ribonuclease HII/HIII domain CIG75_RS04775 914f3086b128d9011bc926fbb7e61f39 356 SUPERFAMILY SSF53098 145 354 7.28E-38 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CIG75_RS04775 914f3086b128d9011bc926fbb7e61f39 356 Gene3D G3DSA:3.30.420.10 122 356 7.7E-37 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CIG75_RS14805 eb8fa6c36950c36cbb776b001c286433 370 SMART SM00271 4 62 5.0E-30 T 28-03-2018 IPR001623 DnaJ domain CIG75_RS14805 eb8fa6c36950c36cbb776b001c286433 370 SUPERFAMILY SSF57938 126 207 1.11E-18 T 28-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 CIG75_RS14805 eb8fa6c36950c36cbb776b001c286433 370 Gene3D G3DSA:1.10.287.110 1 106 2.7E-34 T 28-03-2018 IPR001623 DnaJ domain CIG75_RS14805 eb8fa6c36950c36cbb776b001c286433 370 SUPERFAMILY SSF46565 2 103 9.94E-35 T 28-03-2018 IPR001623 DnaJ domain CIG75_RS14805 eb8fa6c36950c36cbb776b001c286433 370 SUPERFAMILY SSF49493 254 341 1.11E-25 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CIG75_RS14805 eb8fa6c36950c36cbb776b001c286433 370 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 5 346 2.4E-136 T 28-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 CIG75_RS14805 eb8fa6c36950c36cbb776b001c286433 370 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 2 366 40.589 T 28-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 CIG75_RS14805 eb8fa6c36950c36cbb776b001c286433 370 Pfam PF00684 DnaJ central domain 139 203 3.1E-12 T 28-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 CIG75_RS14805 eb8fa6c36950c36cbb776b001c286433 370 Gene3D G3DSA:2.60.260.20 177 250 7.3E-17 T 28-03-2018 CIG75_RS14805 eb8fa6c36950c36cbb776b001c286433 370 Gene3D G3DSA:2.60.260.20 107 176 6.3E-14 T 28-03-2018 CIG75_RS14805 eb8fa6c36950c36cbb776b001c286433 370 Pfam PF01556 DnaJ C terminal domain 112 330 2.3E-43 T 28-03-2018 IPR002939 Chaperone DnaJ, C-terminal CIG75_RS14805 eb8fa6c36950c36cbb776b001c286433 370 ProSitePatterns PS00636 Nt-dnaJ domain signature. 47 66 - T 28-03-2018 IPR018253 DnaJ domain, conserved site CIG75_RS14805 eb8fa6c36950c36cbb776b001c286433 370 SUPERFAMILY SSF49493 106 147 2.09E-17 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CIG75_RS14805 eb8fa6c36950c36cbb776b001c286433 370 SUPERFAMILY SSF49493 210 253 2.09E-17 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CIG75_RS14805 eb8fa6c36950c36cbb776b001c286433 370 Pfam PF00226 DnaJ domain 5 67 5.4E-27 T 28-03-2018 IPR001623 DnaJ domain CIG75_RS14805 eb8fa6c36950c36cbb776b001c286433 370 PRINTS PR00625 DnaJ domain signature 62 81 2.9E-29 T 28-03-2018 IPR001623 DnaJ domain CIG75_RS14805 eb8fa6c36950c36cbb776b001c286433 370 PRINTS PR00625 DnaJ domain signature 42 62 2.9E-29 T 28-03-2018 IPR001623 DnaJ domain CIG75_RS14805 eb8fa6c36950c36cbb776b001c286433 370 PRINTS PR00625 DnaJ domain signature 7 25 2.9E-29 T 28-03-2018 IPR001623 DnaJ domain CIG75_RS14805 eb8fa6c36950c36cbb776b001c286433 370 PRINTS PR00625 DnaJ domain signature 25 40 2.9E-29 T 28-03-2018 IPR001623 DnaJ domain CIG75_RS14805 eb8fa6c36950c36cbb776b001c286433 370 Gene3D G3DSA:2.60.260.20 251 362 4.0E-31 T 28-03-2018 CIG75_RS11865 dad41293e82acbd16d014483bfdd89a4 390 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 144 227 2.5E-39 T 28-03-2018 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CIG75_RS11865 dad41293e82acbd16d014483bfdd89a4 390 SUPERFAMILY SSF51735 3 148 9.87E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS11865 dad41293e82acbd16d014483bfdd89a4 390 Gene3D G3DSA:1.10.1740.10 300 384 1.4E-28 T 28-03-2018 CIG75_RS11865 dad41293e82acbd16d014483bfdd89a4 390 Gene3D G3DSA:3.40.50.720 2 148 2.5E-53 T 28-03-2018 CIG75_RS11865 dad41293e82acbd16d014483bfdd89a4 390 Pfam PF13288 DXP reductoisomerase C-terminal domain 259 375 6.9E-41 T 28-03-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CIG75_RS11865 dad41293e82acbd16d014483bfdd89a4 390 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 5 380 47.348 T 28-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CIG75_RS11865 dad41293e82acbd16d014483bfdd89a4 390 PIRSF PIRSF006205 2 386 1.3E-158 T 28-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CIG75_RS11865 dad41293e82acbd16d014483bfdd89a4 390 SUPERFAMILY SSF55347 124 262 1.5E-59 T 28-03-2018 CIG75_RS11865 dad41293e82acbd16d014483bfdd89a4 390 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 4 381 1.4E-159 T 28-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CIG75_RS11865 dad41293e82acbd16d014483bfdd89a4 390 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 5 130 3.2E-44 T 28-03-2018 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CIG75_RS11865 dad41293e82acbd16d014483bfdd89a4 390 SUPERFAMILY SSF69055 289 383 1.83E-31 T 28-03-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CIG75_RS17165 2df976518ed94e2475b6d418c006ecf7 314 Pfam PF10298 WhiA N-terminal LAGLIDADG-like domain 18 102 9.9E-35 T 28-03-2018 IPR018478 Sporulation transcription regulator WhiA, N-terminal domain CIG75_RS17165 2df976518ed94e2475b6d418c006ecf7 314 Gene3D G3DSA:3.10.28.10 112 223 1.0E-16 T 28-03-2018 IPR027434 Homing endonuclease GO:0004519 CIG75_RS17165 2df976518ed94e2475b6d418c006ecf7 314 Pfam PF02650 WhiA C-terminal HTH domain 220 303 1.1E-34 T 28-03-2018 IPR023054 Sporulation regulator WhiA, C-terminal CIG75_RS17165 2df976518ed94e2475b6d418c006ecf7 314 SUPERFAMILY SSF55608 120 221 2.17E-18 T 28-03-2018 IPR027434 Homing endonuclease GO:0004519 CIG75_RS17165 2df976518ed94e2475b6d418c006ecf7 314 Gene3D G3DSA:3.10.28.10 13 101 1.9E-14 T 28-03-2018 IPR027434 Homing endonuclease GO:0004519 CIG75_RS17165 2df976518ed94e2475b6d418c006ecf7 314 TIGRFAM TIGR00647 DNA_bind_WhiA: DNA-binding protein WhiA 4 304 6.5E-121 T 28-03-2018 IPR033981 Sporulation regulator WhiA-like CIG75_RS17165 2df976518ed94e2475b6d418c006ecf7 314 Pfam PF14527 WhiA LAGLIDADG-like domain 125 217 7.3E-36 T 28-03-2018 CIG75_RS17165 2df976518ed94e2475b6d418c006ecf7 314 Hamap MF_01420 Putative sporulation transcription regulator WhiA [whiA]. 3 306 34.839 T 28-03-2018 IPR003802 Sporulation regulator WhiA GO:0043937 CIG75_RS05975 8ed0b92f8fefd85d05e767b4f0fc2a47 422 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 311 421 7.6E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS05975 8ed0b92f8fefd85d05e767b4f0fc2a47 422 SUPERFAMILY SSF47384 193 266 5.49E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CIG75_RS05975 8ed0b92f8fefd85d05e767b4f0fc2a47 422 Gene3D G3DSA:1.10.287.130 192 261 6.8E-16 T 28-03-2018 CIG75_RS05975 8ed0b92f8fefd85d05e767b4f0fc2a47 422 SMART SM00387 310 422 2.5E-40 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS05975 8ed0b92f8fefd85d05e767b4f0fc2a47 422 SUPERFAMILY SSF55874 255 420 5.5E-48 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS05975 8ed0b92f8fefd85d05e767b4f0fc2a47 422 SMART SM00388 198 265 1.0E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CIG75_RS05975 8ed0b92f8fefd85d05e767b4f0fc2a47 422 Pfam PF00512 His Kinase A (phospho-acceptor) domain 199 264 3.5E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CIG75_RS05975 8ed0b92f8fefd85d05e767b4f0fc2a47 422 Gene3D G3DSA:3.30.565.10 269 422 3.9E-44 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS05975 8ed0b92f8fefd85d05e767b4f0fc2a47 422 PRINTS PR00344 Bacterial sensor protein C-terminal signature 406 419 5.5E-18 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS05975 8ed0b92f8fefd85d05e767b4f0fc2a47 422 PRINTS PR00344 Bacterial sensor protein C-terminal signature 347 361 5.5E-18 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS05975 8ed0b92f8fefd85d05e767b4f0fc2a47 422 PRINTS PR00344 Bacterial sensor protein C-terminal signature 365 375 5.5E-18 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS05975 8ed0b92f8fefd85d05e767b4f0fc2a47 422 PRINTS PR00344 Bacterial sensor protein C-terminal signature 382 400 5.5E-18 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS00565 c6dfe6385ed25c5286b81dc7713fb3c4 389 SMART SM00228 296 377 1.0E-5 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CIG75_RS00565 c6dfe6385ed25c5286b81dc7713fb3c4 389 Pfam PF13365 Trypsin-like peptidase domain 113 258 1.2E-33 T 28-03-2018 CIG75_RS00565 c6dfe6385ed25c5286b81dc7713fb3c4 389 Gene3D G3DSA:2.40.10.10 72 181 3.3E-34 T 28-03-2018 CIG75_RS00565 c6dfe6385ed25c5286b81dc7713fb3c4 389 Gene3D G3DSA:2.30.42.10 294 389 2.7E-17 T 28-03-2018 CIG75_RS00565 c6dfe6385ed25c5286b81dc7713fb3c4 389 Gene3D G3DSA:2.40.10.10 182 290 1.9E-35 T 28-03-2018 CIG75_RS00565 c6dfe6385ed25c5286b81dc7713fb3c4 389 PRINTS PR00834 HtrA/DegQ protease family signature 335 347 3.6E-43 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CIG75_RS00565 c6dfe6385ed25c5286b81dc7713fb3c4 389 PRINTS PR00834 HtrA/DegQ protease family signature 251 268 3.6E-43 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CIG75_RS00565 c6dfe6385ed25c5286b81dc7713fb3c4 389 PRINTS PR00834 HtrA/DegQ protease family signature 122 134 3.6E-43 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CIG75_RS00565 c6dfe6385ed25c5286b81dc7713fb3c4 389 PRINTS PR00834 HtrA/DegQ protease family signature 186 210 3.6E-43 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CIG75_RS00565 c6dfe6385ed25c5286b81dc7713fb3c4 389 PRINTS PR00834 HtrA/DegQ protease family signature 143 163 3.6E-43 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CIG75_RS00565 c6dfe6385ed25c5286b81dc7713fb3c4 389 PRINTS PR00834 HtrA/DegQ protease family signature 229 246 3.6E-43 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CIG75_RS00565 c6dfe6385ed25c5286b81dc7713fb3c4 389 SUPERFAMILY SSF50156 277 386 8.68E-18 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CIG75_RS00565 c6dfe6385ed25c5286b81dc7713fb3c4 389 Pfam PF13180 PDZ domain 296 386 2.2E-16 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CIG75_RS00565 c6dfe6385ed25c5286b81dc7713fb3c4 389 SUPERFAMILY SSF50494 77 292 3.64E-60 T 28-03-2018 IPR009003 Peptidase S1, PA clan CIG75_RS14800 05cf04b2f7ce37d3ef13ca08cd059d63 314 TIGRFAM TIGR00406 prmA: ribosomal protein L11 methyltransferase 3 305 1.4E-85 T 28-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 CIG75_RS14800 05cf04b2f7ce37d3ef13ca08cd059d63 314 PIRSF PIRSF000401 1 313 1.1E-106 T 28-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 CIG75_RS14800 05cf04b2f7ce37d3ef13ca08cd059d63 314 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 2 311 2.8E-100 T 28-03-2018 CIG75_RS14800 05cf04b2f7ce37d3ef13ca08cd059d63 314 Gene3D G3DSA:3.40.50.150 116 314 4.1E-49 T 28-03-2018 CIG75_RS14800 05cf04b2f7ce37d3ef13ca08cd059d63 314 SUPERFAMILY SSF53335 99 310 9.77E-48 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CIG75_RS14800 05cf04b2f7ce37d3ef13ca08cd059d63 314 Hamap MF_00735 Ribosomal protein L11 methyltransferase [prmA]. 3 311 36.545 T 28-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 CIG75_RS02880 d7845bd0a9fba399c039f01f2b82d34a 1432 ProSitePatterns PS00622 LuxR-type HTH domain signature. 1384 1411 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CIG75_RS02880 d7845bd0a9fba399c039f01f2b82d34a 1432 SMART SM00421 1367 1424 7.2E-21 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CIG75_RS02880 d7845bd0a9fba399c039f01f2b82d34a 1432 Gene3D G3DSA:3.40.50.300 199 408 3.6E-6 T 28-03-2018 CIG75_RS02880 d7845bd0a9fba399c039f01f2b82d34a 1432 Gene3D G3DSA:3.30.450.40 1186 1339 7.3E-11 T 28-03-2018 IPR029016 GAF domain-like CIG75_RS02880 d7845bd0a9fba399c039f01f2b82d34a 1432 Gene3D G3DSA:1.10.510.10 7 178 1.7E-16 T 28-03-2018 CIG75_RS02880 d7845bd0a9fba399c039f01f2b82d34a 1432 Pfam PF00069 Protein kinase domain 65 157 5.2E-7 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CIG75_RS02880 d7845bd0a9fba399c039f01f2b82d34a 1432 SUPERFAMILY SSF56112 9 165 9.8E-20 T 28-03-2018 IPR011009 Protein kinase-like domain CIG75_RS02880 d7845bd0a9fba399c039f01f2b82d34a 1432 Pfam PF00196 Bacterial regulatory proteins, luxR family 1369 1423 7.7E-16 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CIG75_RS02880 d7845bd0a9fba399c039f01f2b82d34a 1432 SUPERFAMILY SSF55781 1194 1334 3.24E-8 T 28-03-2018 IPR029016 GAF domain-like CIG75_RS02880 d7845bd0a9fba399c039f01f2b82d34a 1432 SUPERFAMILY SSF52540 196 458 4.98E-9 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS02880 d7845bd0a9fba399c039f01f2b82d34a 1432 Pfam PF13191 AAA ATPase domain 198 386 1.8E-23 T 28-03-2018 CIG75_RS02880 d7845bd0a9fba399c039f01f2b82d34a 1432 SUPERFAMILY SSF46894 1357 1430 2.65E-20 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CIG75_RS02880 d7845bd0a9fba399c039f01f2b82d34a 1432 Gene3D G3DSA:1.25.40.10 622 1182 2.9E-15 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS02880 d7845bd0a9fba399c039f01f2b82d34a 1432 Gene3D G3DSA:1.10.10.10 1359 1432 1.3E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS02880 d7845bd0a9fba399c039f01f2b82d34a 1432 Gene3D G3DSA:1.10.10.10 446 621 0.011 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS02880 d7845bd0a9fba399c039f01f2b82d34a 1432 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 1370 1384 3.6E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CIG75_RS02880 d7845bd0a9fba399c039f01f2b82d34a 1432 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 1400 1412 3.6E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CIG75_RS02880 d7845bd0a9fba399c039f01f2b82d34a 1432 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 1384 1400 3.6E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CIG75_RS16970 ab5417fceef5aeac8700c148797805a5 221 Pfam PF02586 SOS response associated peptidase (SRAP) 1 210 8.5E-69 T 28-03-2018 IPR003738 SOS response associated peptidase (SRAP) CIG75_RS16970 ab5417fceef5aeac8700c148797805a5 221 Gene3D G3DSA:3.90.1680.10 1 221 2.1E-81 T 28-03-2018 IPR003738 SOS response associated peptidase (SRAP) CIG75_RS16970 ab5417fceef5aeac8700c148797805a5 221 SUPERFAMILY SSF143081 2 220 6.28E-78 T 28-03-2018 IPR003738 SOS response associated peptidase (SRAP) CIG75_RS11275 d9e16d902ac164416a8f959462bb0d8d 276 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 11 272 3.3E-87 T 28-03-2018 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 CIG75_RS11275 d9e16d902ac164416a8f959462bb0d8d 276 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 64 271 8.2E-57 T 28-03-2018 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 CIG75_RS11275 d9e16d902ac164416a8f959462bb0d8d 276 TIGRFAM TIGR02139 permease_CysT: sulfate ABC transporter, permease protein CysT 21 274 2.9E-84 T 28-03-2018 IPR011865 Sulphate ABC transporter, permease protein CysT GO:0008272|GO:0015116|GO:0016021 CIG75_RS11275 d9e16d902ac164416a8f959462bb0d8d 276 Gene3D G3DSA:1.10.3720.10 21 276 4.7E-47 T 28-03-2018 CIG75_RS11275 d9e16d902ac164416a8f959462bb0d8d 276 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 78 273 3.0E-24 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CIG75_RS11275 d9e16d902ac164416a8f959462bb0d8d 276 SUPERFAMILY SSF161098 13 269 3.18E-59 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CIG75_RS07265 df1cd375a391554524cf9ae7792618c6 371 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 7 333 3.2E-48 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CIG75_RS07265 df1cd375a391554524cf9ae7792618c6 371 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 4 20 8.0E-13 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CIG75_RS07265 df1cd375a391554524cf9ae7792618c6 371 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 163 176 8.0E-13 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CIG75_RS07265 df1cd375a391554524cf9ae7792618c6 371 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 114 128 8.0E-13 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CIG75_RS07265 df1cd375a391554524cf9ae7792618c6 371 ProSitePatterns PS00094 C-5 cytosine-specific DNA methylases active site. 75 87 - T 28-03-2018 IPR018117 DNA methylase, C-5 cytosine-specific, active site KEGG: 00270+2.1.1.37|Reactome: R-HSA-212300|Reactome: R-HSA-5334118 CIG75_RS07265 df1cd375a391554524cf9ae7792618c6 371 SUPERFAMILY SSF53335 3 336 4.43E-74 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CIG75_RS07265 df1cd375a391554524cf9ae7792618c6 371 Gene3D G3DSA:3.40.50.150 2 246 9.0E-51 T 28-03-2018 CIG75_RS07265 df1cd375a391554524cf9ae7792618c6 371 Pfam PF00145 C-5 cytosine-specific DNA methylase 3 334 1.5E-70 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CIG75_RS17610 7d45bb94e50024db0db8cbccbc861401 362 Gene3D G3DSA:3.50.30.20 1 138 1.8E-56 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CIG75_RS17610 7d45bb94e50024db0db8cbccbc861401 362 SUPERFAMILY SSF52317 142 354 8.56E-62 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CIG75_RS17610 7d45bb94e50024db0db8cbccbc861401 362 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 1 354 47.188 T 28-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CIG75_RS17610 7d45bb94e50024db0db8cbccbc861401 362 PRINTS PR00096 Glutamine amidotransferase superfamily signature 240 251 7.6E-13 T 28-03-2018 CIG75_RS17610 7d45bb94e50024db0db8cbccbc861401 362 PRINTS PR00096 Glutamine amidotransferase superfamily signature 325 338 7.6E-13 T 28-03-2018 CIG75_RS17610 7d45bb94e50024db0db8cbccbc861401 362 PRINTS PR00096 Glutamine amidotransferase superfamily signature 213 222 7.6E-13 T 28-03-2018 CIG75_RS17610 7d45bb94e50024db0db8cbccbc861401 362 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 3 130 3.0E-50 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CIG75_RS17610 7d45bb94e50024db0db8cbccbc861401 362 SMART SM01097 1 131 6.6E-77 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CIG75_RS17610 7d45bb94e50024db0db8cbccbc861401 362 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 171 185 2.7E-36 T 28-03-2018 CIG75_RS17610 7d45bb94e50024db0db8cbccbc861401 362 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 240 256 2.7E-36 T 28-03-2018 CIG75_RS17610 7d45bb94e50024db0db8cbccbc861401 362 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 210 224 2.7E-36 T 28-03-2018 CIG75_RS17610 7d45bb94e50024db0db8cbccbc861401 362 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 282 293 2.7E-36 T 28-03-2018 CIG75_RS17610 7d45bb94e50024db0db8cbccbc861401 362 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 257 274 2.7E-36 T 28-03-2018 CIG75_RS17610 7d45bb94e50024db0db8cbccbc861401 362 Gene3D G3DSA:3.40.50.880 139 355 3.3E-58 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CIG75_RS17610 7d45bb94e50024db0db8cbccbc861401 362 Pfam PF00117 Glutamine amidotransferase class-I 173 347 2.3E-47 T 28-03-2018 IPR017926 Glutamine amidotransferase CIG75_RS17610 7d45bb94e50024db0db8cbccbc861401 362 SUPERFAMILY SSF52021 1 135 4.84E-53 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CIG75_RS17610 7d45bb94e50024db0db8cbccbc861401 362 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 4 351 6.6E-142 T 28-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CIG75_RS01885 cbfe5add891909d1e16b09f785ec868e 416 Gene3D G3DSA:3.40.640.10 33 269 2.7E-54 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CIG75_RS01885 cbfe5add891909d1e16b09f785ec868e 416 PIRSF PIRSF000412 1 414 1.2E-175 T 28-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CIG75_RS01885 cbfe5add891909d1e16b09f785ec868e 416 Pfam PF00464 Serine hydroxymethyltransferase 7 380 3.7E-178 T 28-03-2018 CIG75_RS01885 cbfe5add891909d1e16b09f785ec868e 416 SUPERFAMILY SSF53383 3 412 2.72E-183 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CIG75_RS01885 cbfe5add891909d1e16b09f785ec868e 416 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 218 234 - T 28-03-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CIG75_RS01885 cbfe5add891909d1e16b09f785ec868e 416 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 3 411 54.272 T 28-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CIG75_RS01885 cbfe5add891909d1e16b09f785ec868e 416 Gene3D G3DSA:3.90.1150.10 270 410 4.2E-61 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CIG75_RS06990 e2911fb2e383b9ece6f60c5603370c0b 215 Hamap MF_00551 Uridine kinase [udk]. 1 205 41.905 T 28-03-2018 IPR026008 Uridine kinase GO:0004849|GO:0005524|GO:0016773 KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 CIG75_RS06990 e2911fb2e383b9ece6f60c5603370c0b 215 PRINTS PR00988 Uridine kinase signature 4 21 2.4E-38 T 28-03-2018 CIG75_RS06990 e2911fb2e383b9ece6f60c5603370c0b 215 PRINTS PR00988 Uridine kinase signature 34 45 2.4E-38 T 28-03-2018 CIG75_RS06990 e2911fb2e383b9ece6f60c5603370c0b 215 PRINTS PR00988 Uridine kinase signature 149 160 2.4E-38 T 28-03-2018 CIG75_RS06990 e2911fb2e383b9ece6f60c5603370c0b 215 PRINTS PR00988 Uridine kinase signature 171 184 2.4E-38 T 28-03-2018 CIG75_RS06990 e2911fb2e383b9ece6f60c5603370c0b 215 PRINTS PR00988 Uridine kinase signature 79 94 2.4E-38 T 28-03-2018 CIG75_RS06990 e2911fb2e383b9ece6f60c5603370c0b 215 PRINTS PR00988 Uridine kinase signature 135 145 2.4E-38 T 28-03-2018 CIG75_RS06990 e2911fb2e383b9ece6f60c5603370c0b 215 SMART SM00382 3 154 6.7E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS06990 e2911fb2e383b9ece6f60c5603370c0b 215 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 6 191 2.1E-47 T 28-03-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 Reactome: R-HSA-73614 CIG75_RS06990 e2911fb2e383b9ece6f60c5603370c0b 215 Gene3D G3DSA:3.40.50.300 1 208 1.6E-60 T 28-03-2018 CIG75_RS06990 e2911fb2e383b9ece6f60c5603370c0b 215 SUPERFAMILY SSF52540 2 196 1.03E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS06990 e2911fb2e383b9ece6f60c5603370c0b 215 TIGRFAM TIGR00235 udk: uridine kinase 5 204 1.8E-89 T 28-03-2018 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193|Reactome: R-HSA-73614 CIG75_RS08275 40d4cad8ceb1afcda42a7a89e7bf2f5c 152 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 152 67.915 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CIG75_RS08275 40d4cad8ceb1afcda42a7a89e7bf2f5c 152 Gene3D G3DSA:3.40.50.9100 1 146 6.9E-63 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CIG75_RS08275 40d4cad8ceb1afcda42a7a89e7bf2f5c 152 Pfam PF01220 Dehydroquinase class II 3 139 8.3E-60 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CIG75_RS08275 40d4cad8ceb1afcda42a7a89e7bf2f5c 152 SUPERFAMILY SSF52304 3 144 1.1E-59 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CIG75_RS08275 40d4cad8ceb1afcda42a7a89e7bf2f5c 152 PIRSF PIRSF001399 1 146 9.7E-60 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CIG75_RS08275 40d4cad8ceb1afcda42a7a89e7bf2f5c 152 ProSitePatterns PS01029 Dehydroquinase class II signature. 7 24 - T 28-03-2018 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CIG75_RS08275 40d4cad8ceb1afcda42a7a89e7bf2f5c 152 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 3 141 2.4E-60 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CIG75_RS08275 40d4cad8ceb1afcda42a7a89e7bf2f5c 152 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 4 146 7.0E-46 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CIG75_RS10640 7df86a35fb934a3ebd9cd51ca926fe9a 1129 Gene3D G3DSA:1.10.1200.10 1028 1093 1.1E-19 T 28-03-2018 CIG75_RS10640 7df86a35fb934a3ebd9cd51ca926fe9a 1129 SMART SM00823 Phosphopantetheine attachment site 1021 1090 6.2E-4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS10640 7df86a35fb934a3ebd9cd51ca926fe9a 1129 Gene3D G3DSA:3.40.50.980 645 797 4.1E-40 T 28-03-2018 CIG75_RS10640 7df86a35fb934a3ebd9cd51ca926fe9a 1129 SUPERFAMILY SSF56801 455 1034 1.44E-159 T 28-03-2018 CIG75_RS10640 7df86a35fb934a3ebd9cd51ca926fe9a 1129 Gene3D G3DSA:3.30.300.30 892 1027 8.5E-31 T 28-03-2018 CIG75_RS10640 7df86a35fb934a3ebd9cd51ca926fe9a 1129 ProSitePatterns PS00455 Putative AMP-binding domain signature. 639 650 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS10640 7df86a35fb934a3ebd9cd51ca926fe9a 1129 SUPERFAMILY SSF52777 37 213 2.22E-49 T 28-03-2018 CIG75_RS10640 7df86a35fb934a3ebd9cd51ca926fe9a 1129 SUPERFAMILY SSF52777 224 466 2.33E-65 T 28-03-2018 CIG75_RS10640 7df86a35fb934a3ebd9cd51ca926fe9a 1129 Pfam PF00668 Condensation domain 33 477 3.0E-107 T 28-03-2018 IPR001242 Condensation domain CIG75_RS10640 7df86a35fb934a3ebd9cd51ca926fe9a 1129 Pfam PF00501 AMP-binding enzyme 497 897 4.3E-109 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS10640 7df86a35fb934a3ebd9cd51ca926fe9a 1129 SUPERFAMILY SSF47336 1014 1086 1.1E-18 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10640 7df86a35fb934a3ebd9cd51ca926fe9a 1129 Pfam PF00550 Phosphopantetheine attachment site 1024 1086 2.1E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10640 7df86a35fb934a3ebd9cd51ca926fe9a 1129 Gene3D G3DSA:3.40.50.980 488 644 8.0E-52 T 28-03-2018 CIG75_RS10640 7df86a35fb934a3ebd9cd51ca926fe9a 1129 Gene3D G3DSA:2.30.38.10 798 889 2.2E-25 T 28-03-2018 CIG75_RS10640 7df86a35fb934a3ebd9cd51ca926fe9a 1129 PIRSF PIRSF001617 223 608 4.2E-21 T 28-03-2018 CIG75_RS10640 7df86a35fb934a3ebd9cd51ca926fe9a 1129 PIRSF PIRSF001617 624 1123 2.8E-60 T 28-03-2018 CIG75_RS10640 7df86a35fb934a3ebd9cd51ca926fe9a 1129 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 518 921 6.3E-137 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS10640 7df86a35fb934a3ebd9cd51ca926fe9a 1129 Gene3D G3DSA:3.30.559.10 11 235 1.4E-40 T 28-03-2018 CIG75_RS12915 3ffed4a79903dd5ca95623bea48bc5b6 612 Pfam PF13361 UvrD-like helicase C-terminal domain 258 586 4.9E-53 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CIG75_RS12915 3ffed4a79903dd5ca95623bea48bc5b6 612 Pfam PF00580 UvrD/REP helicase N-terminal domain 147 251 3.8E-28 T 28-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 CIG75_RS12915 3ffed4a79903dd5ca95623bea48bc5b6 612 Pfam PF00580 UvrD/REP helicase N-terminal domain 4 135 9.4E-31 T 28-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 CIG75_RS12915 3ffed4a79903dd5ca95623bea48bc5b6 612 Gene3D G3DSA:3.40.50.300 254 610 6.0E-58 T 28-03-2018 CIG75_RS12915 3ffed4a79903dd5ca95623bea48bc5b6 612 SUPERFAMILY SSF52540 2 609 7.17E-133 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS12915 3ffed4a79903dd5ca95623bea48bc5b6 612 Gene3D G3DSA:3.40.50.300 1 253 6.8E-51 T 28-03-2018 CIG75_RS06805 8bd67de436e90770b25e54c3bf5aff82 109 Gene3D G3DSA:3.40.30.10 74 109 4.6E-5 T 28-03-2018 CIG75_RS06805 8bd67de436e90770b25e54c3bf5aff82 109 SUPERFAMILY SSF52833 3 108 2.01E-38 T 28-03-2018 IPR012336 Thioredoxin-like fold CIG75_RS06805 8bd67de436e90770b25e54c3bf5aff82 109 PIRSF PIRSF000077 3 109 1.3E-41 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 CIG75_RS06805 8bd67de436e90770b25e54c3bf5aff82 109 Gene3D G3DSA:3.40.30.10 6 73 9.4E-28 T 28-03-2018 CIG75_RS06805 8bd67de436e90770b25e54c3bf5aff82 109 Pfam PF00085 Thioredoxin 6 106 1.4E-31 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 CIG75_RS06805 8bd67de436e90770b25e54c3bf5aff82 109 ProSitePatterns PS00194 Thioredoxin family active site. 26 44 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 CIG75_RS06805 8bd67de436e90770b25e54c3bf5aff82 109 PRINTS PR00421 Thioredoxin family signature 33 42 3.9E-9 T 28-03-2018 CIG75_RS06805 8bd67de436e90770b25e54c3bf5aff82 109 PRINTS PR00421 Thioredoxin family signature 73 84 3.9E-9 T 28-03-2018 CIG75_RS06805 8bd67de436e90770b25e54c3bf5aff82 109 PRINTS PR00421 Thioredoxin family signature 25 33 3.9E-9 T 28-03-2018 CIG75_RS06805 8bd67de436e90770b25e54c3bf5aff82 109 TIGRFAM TIGR01068 thioredoxin: thioredoxin 10 107 1.9E-38 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 CIG75_RS05640 08921872d9483f9f10ca740c45362df7 177 Gene3D G3DSA:3.40.50.2020 1 177 1.8E-38 T 28-03-2018 CIG75_RS05640 08921872d9483f9f10ca740c45362df7 177 Pfam PF00156 Phosphoribosyl transferase domain 9 156 3.5E-27 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CIG75_RS05640 08921872d9483f9f10ca740c45362df7 177 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 8 171 1.0E-55 T 28-03-2018 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 CIG75_RS05640 08921872d9483f9f10ca740c45362df7 177 SUPERFAMILY SSF53271 7 172 1.06E-49 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CIG75_RS10260 ba02b558808f978cec60ab50a3bacb2b 322 Gene3D G3DSA:1.10.443.10 134 309 8.2E-37 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CIG75_RS10260 ba02b558808f978cec60ab50a3bacb2b 322 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 43 105 2.5E-7 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CIG75_RS10260 ba02b558808f978cec60ab50a3bacb2b 322 SUPERFAMILY SSF56349 33 306 3.24E-50 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CIG75_RS10260 ba02b558808f978cec60ab50a3bacb2b 322 Pfam PF00589 Phage integrase family 137 305 5.0E-25 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CIG75_RS10260 ba02b558808f978cec60ab50a3bacb2b 322 Gene3D G3DSA:1.10.150.130 32 133 7.0E-16 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CIG75_RS09310 36b78c692d755b121eba441cfe33c9bb 325 SMART SM00870 3 319 3.3E-142 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CIG75_RS09310 36b78c692d755b121eba441cfe33c9bb 325 Pfam PF00710 Asparaginase, N-terminal 4 190 1.7E-61 T 28-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 CIG75_RS09310 36b78c692d755b121eba441cfe33c9bb 325 PIRSF PIRSF500176 1 325 3.5E-93 T 28-03-2018 CIG75_RS09310 36b78c692d755b121eba441cfe33c9bb 325 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 82 92 - T 28-03-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 CIG75_RS09310 36b78c692d755b121eba441cfe33c9bb 325 PIRSF PIRSF001220 1 325 3.6E-97 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CIG75_RS09310 36b78c692d755b121eba441cfe33c9bb 325 Gene3D G3DSA:3.40.50.40 207 324 2.5E-32 T 28-03-2018 IPR027473 L-asparaginase, C-terminal domain Reactome: R-HSA-70614 CIG75_RS09310 36b78c692d755b121eba441cfe33c9bb 325 PRINTS PR00139 Asparaginase/glutaminase family signature 254 272 9.4E-20 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CIG75_RS09310 36b78c692d755b121eba441cfe33c9bb 325 PRINTS PR00139 Asparaginase/glutaminase family signature 81 99 9.4E-20 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CIG75_RS09310 36b78c692d755b121eba441cfe33c9bb 325 PRINTS PR00139 Asparaginase/glutaminase family signature 4 15 9.4E-20 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CIG75_RS09310 36b78c692d755b121eba441cfe33c9bb 325 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 6 14 - T 28-03-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 CIG75_RS09310 36b78c692d755b121eba441cfe33c9bb 325 SUPERFAMILY SSF53774 1 324 2.62E-105 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CIG75_RS09310 36b78c692d755b121eba441cfe33c9bb 325 Gene3D G3DSA:3.40.50.1170 1 201 5.2E-57 T 28-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 CIG75_RS06085 d88a80db95e1716fb36af27d17fec727 285 SUPERFAMILY SSF56281 84 272 1.04E-43 T 28-03-2018 IPR001279 Metallo-beta-lactamase CIG75_RS06085 d88a80db95e1716fb36af27d17fec727 285 SMART SM00849 103 261 3.1E-15 T 28-03-2018 IPR001279 Metallo-beta-lactamase CIG75_RS06085 d88a80db95e1716fb36af27d17fec727 285 SUPERFAMILY SSF54862 18 70 2.58E-6 T 28-03-2018 CIG75_RS06085 d88a80db95e1716fb36af27d17fec727 285 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 16 69 1.4E-14 T 28-03-2018 CIG75_RS06085 d88a80db95e1716fb36af27d17fec727 285 Gene3D G3DSA:3.60.15.10 87 281 9.1E-25 T 28-03-2018 IPR001279 Metallo-beta-lactamase CIG75_RS02715 91fe252cbc762334f8aa14bdd98b6f69 498 Pfam PF00668 Condensation domain 52 489 2.7E-79 T 28-03-2018 IPR001242 Condensation domain CIG75_RS02715 91fe252cbc762334f8aa14bdd98b6f69 498 SUPERFAMILY SSF52777 49 251 3.56E-36 T 28-03-2018 CIG75_RS02715 91fe252cbc762334f8aa14bdd98b6f69 498 Gene3D G3DSA:3.30.559.10 42 245 1.4E-26 T 28-03-2018 CIG75_RS02715 91fe252cbc762334f8aa14bdd98b6f69 498 SUPERFAMILY SSF47336 1 36 9.03E-5 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS02715 91fe252cbc762334f8aa14bdd98b6f69 498 SUPERFAMILY SSF52777 243 489 2.11E-37 T 28-03-2018 CIG75_RS02715 91fe252cbc762334f8aa14bdd98b6f69 498 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 364 488 1.3E-21 T 28-03-2018 IPR010060 Non-ribosomal peptide synthase CIG75_RS02715 91fe252cbc762334f8aa14bdd98b6f69 498 Gene3D G3DSA:1.10.1200.10 1 37 5.9E-6 T 28-03-2018 CIG75_RS09455 1276d0c467c009b51419db3e8d1fe572 275 Pfam PF13102 Phage integrase SAM-like domain 23 136 7.7E-9 T 28-03-2018 IPR025269 Phage integrase SAM-like domain CIG75_RS09455 1276d0c467c009b51419db3e8d1fe572 275 Pfam PF00589 Phage integrase family 148 270 4.2E-19 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CIG75_RS09455 1276d0c467c009b51419db3e8d1fe572 275 SUPERFAMILY SSF56349 25 271 3.53E-38 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CIG75_RS09455 1276d0c467c009b51419db3e8d1fe572 275 Gene3D G3DSA:1.10.150.130 16 151 2.0E-18 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CIG75_RS09455 1276d0c467c009b51419db3e8d1fe572 275 Gene3D G3DSA:1.10.443.10 152 274 2.6E-22 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CIG75_RS19670 4b5edfd333e9f09db81d5409df053cfb 61 Pfam PF00253 Ribosomal protein S14p/S29e 9 60 6.5E-27 T 28-03-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS19670 4b5edfd333e9f09db81d5409df053cfb 61 ProSitePatterns PS00527 Ribosomal protein S14 signature. 23 45 - T 28-03-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CIG75_RS19670 4b5edfd333e9f09db81d5409df053cfb 61 Gene3D G3DSA:4.10.830.10 1 61 1.1E-22 T 28-03-2018 CIG75_RS19670 4b5edfd333e9f09db81d5409df053cfb 61 Hamap MF_01364_B 30S ribosomal protein S14 type Z [rpsZ]. 1 61 26.433 T 28-03-2018 IPR023053 Ribosomal protein S14, type Z CIG75_RS19670 4b5edfd333e9f09db81d5409df053cfb 61 SUPERFAMILY SSF57716 5 61 3.28E-22 T 28-03-2018 CIG75_RS04170 6af98742c607f23fccb56e72c5e72691 142 Gene3D G3DSA:3.40.50.2300 2 141 1.8E-38 T 28-03-2018 CIG75_RS04170 6af98742c607f23fccb56e72c5e72691 142 SUPERFAMILY SSF52788 8 139 1.26E-43 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CIG75_RS04170 6af98742c607f23fccb56e72c5e72691 142 TIGRFAM TIGR02691 arsC_pI258_fam: arsenate reductase (thioredoxin) 8 136 2.8E-66 T 28-03-2018 IPR014064 Arsenate reductase ArsC GO:0004725|GO:0030612|GO:0046685 CIG75_RS04170 6af98742c607f23fccb56e72c5e72691 142 SMART SM00226 6 139 9.0E-55 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CIG75_RS04170 6af98742c607f23fccb56e72c5e72691 142 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 8 136 4.8E-21 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CIG75_RS07980 91107ab8014ea1aebab4a9abcae973f6 357 Pfam PF00483 Nucleotidyl transferase 4 281 1.8E-44 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CIG75_RS07980 91107ab8014ea1aebab4a9abcae973f6 357 Gene3D G3DSA:3.90.550.10 1 352 1.2E-86 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CIG75_RS07980 91107ab8014ea1aebab4a9abcae973f6 357 SUPERFAMILY SSF53448 1 280 1.97E-65 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CIG75_RS07980 91107ab8014ea1aebab4a9abcae973f6 357 Pfam PF01050 Mannose-6-phosphate isomerase 316 354 2.4E-5 T 28-03-2018 IPR001538 Mannose-6-phosphate isomerase, type II, C-terminal GO:0005976|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 CIG75_RS07980 91107ab8014ea1aebab4a9abcae973f6 357 SUPERFAMILY SSF159283 285 349 7.06E-15 T 28-03-2018 CIG75_RS10740 a6b48f45988b40ccb4bf73956d2b4bd6 1065 SUPERFAMILY SSF58104 493 737 7.06E-7 T 28-03-2018 CIG75_RS10740 a6b48f45988b40ccb4bf73956d2b4bd6 1065 SUPERFAMILY SSF82866 144 361 5.1E-34 T 28-03-2018 CIG75_RS10740 a6b48f45988b40ccb4bf73956d2b4bd6 1065 SUPERFAMILY SSF82866 839 1048 6.28E-34 T 28-03-2018 CIG75_RS10740 a6b48f45988b40ccb4bf73956d2b4bd6 1065 Gene3D G3DSA:1.20.120.570 617 784 4.2E-20 T 28-03-2018 CIG75_RS10740 a6b48f45988b40ccb4bf73956d2b4bd6 1065 Gene3D G3DSA:1.20.120.570 444 616 7.8E-15 T 28-03-2018 CIG75_RS10740 a6b48f45988b40ccb4bf73956d2b4bd6 1065 Pfam PF03176 MMPL family 708 1052 1.0E-53 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CIG75_RS10740 a6b48f45988b40ccb4bf73956d2b4bd6 1065 Pfam PF03176 MMPL family 59 389 1.8E-66 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CIG75_RS10740 a6b48f45988b40ccb4bf73956d2b4bd6 1065 Gene3D G3DSA:1.20.1640.10 136 358 2.5E-35 T 28-03-2018 CIG75_RS10740 a6b48f45988b40ccb4bf73956d2b4bd6 1065 Gene3D G3DSA:1.20.1640.10 822 1044 2.6E-29 T 28-03-2018 CIG75_RS19795 50cb622a6a4df9c9a5f5320b044824d2 141 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 36 73 1.0E-14 T 28-03-2018 CIG75_RS19795 50cb622a6a4df9c9a5f5320b044824d2 141 Pfam PF00298 Ribosomal protein L11, RNA binding domain 71 139 5.2E-25 T 28-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 CIG75_RS19795 50cb622a6a4df9c9a5f5320b044824d2 141 Gene3D G3DSA:3.30.1550.10 3 71 5.2E-36 T 28-03-2018 IPR020784 Ribosomal protein L11, N-terminal CIG75_RS19795 50cb622a6a4df9c9a5f5320b044824d2 141 SMART SM00649 9 140 3.8E-86 T 28-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 CIG75_RS19795 50cb622a6a4df9c9a5f5320b044824d2 141 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 5 141 31.268 T 28-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 CIG75_RS19795 50cb622a6a4df9c9a5f5320b044824d2 141 Pfam PF03946 Ribosomal protein L11, N-terminal domain 9 66 2.2E-30 T 28-03-2018 IPR020784 Ribosomal protein L11, N-terminal CIG75_RS19795 50cb622a6a4df9c9a5f5320b044824d2 141 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 3 141 3.1E-65 T 28-03-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS19795 50cb622a6a4df9c9a5f5320b044824d2 141 SUPERFAMILY SSF54747 3 72 1.2E-29 T 28-03-2018 IPR020784 Ribosomal protein L11, N-terminal CIG75_RS19795 50cb622a6a4df9c9a5f5320b044824d2 141 ProSitePatterns PS00359 Ribosomal protein L11 signature. 126 141 - T 28-03-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CIG75_RS19795 50cb622a6a4df9c9a5f5320b044824d2 141 SUPERFAMILY SSF46906 67 140 5.1E-27 T 28-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 CIG75_RS19795 50cb622a6a4df9c9a5f5320b044824d2 141 Gene3D G3DSA:1.10.10.250 72 140 6.8E-25 T 28-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 CIG75_RS16190 55e3f6a4b43b54d8b94623df777825cf 249 SUPERFAMILY SSF50346 92 155 2.67E-6 T 28-03-2018 IPR011033 PRC-barrel-like CIG75_RS16190 55e3f6a4b43b54d8b94623df777825cf 249 Gene3D G3DSA:3.90.50.10 70 192 1.5E-5 T 28-03-2018 CIG75_RS16190 55e3f6a4b43b54d8b94623df777825cf 249 Gene3D G3DSA:2.30.30.240 1 69 1.8E-7 T 28-03-2018 CIG75_RS16190 55e3f6a4b43b54d8b94623df777825cf 249 SUPERFAMILY SSF50346 6 67 5.02E-6 T 28-03-2018 IPR011033 PRC-barrel-like CIG75_RS08960 623090f42c38b57a2934ca1ceab0b96c 331 Gene3D G3DSA:3.30.310.20 7 125 6.3E-4 T 28-03-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal CIG75_RS08960 623090f42c38b57a2934ca1ceab0b96c 331 Gene3D G3DSA:1.10.1670.10 251 317 3.2E-10 T 28-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CIG75_RS08960 623090f42c38b57a2934ca1ceab0b96c 331 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 136 285 3.3E-17 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CIG75_RS08960 623090f42c38b57a2934ca1ceab0b96c 331 Gene3D G3DSA:1.10.340.30 128 249 1.2E-33 T 28-03-2018 CIG75_RS08960 623090f42c38b57a2934ca1ceab0b96c 331 SUPERFAMILY SSF48150 119 299 9.26E-44 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CIG75_RS08960 623090f42c38b57a2934ca1ceab0b96c 331 SMART SM00478 138 306 1.5E-22 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CIG75_RS18030 ea1a75dfb3505a35d873f027f5983bbd 220 Gene3D G3DSA:3.30.559.10 1 206 5.7E-37 T 28-03-2018 CIG75_RS18030 ea1a75dfb3505a35d873f027f5983bbd 220 PIRSF PIRSF000440 1 210 2.6E-65 T 28-03-2018 IPR001707 Chloramphenicol acetyltransferase GO:0008811 CIG75_RS18030 ea1a75dfb3505a35d873f027f5983bbd 220 SUPERFAMILY SSF52777 2 207 2.97E-60 T 28-03-2018 CIG75_RS18030 ea1a75dfb3505a35d873f027f5983bbd 220 ProDom PD002660 TRANSFERASE CHLORAMPHENICOL ACYLTRANSFERASE ACETYLTRANSFERASE ANTIBIOTIC RESISTANCE PLASMID CAT O-ACETYLTRANSFERASE DIRECT 11 200 7.0E-61 T 28-03-2018 IPR001707 Chloramphenicol acetyltransferase GO:0008811 CIG75_RS18030 ea1a75dfb3505a35d873f027f5983bbd 220 Pfam PF00302 Chloramphenicol acetyltransferase 2 201 4.0E-41 T 28-03-2018 IPR001707 Chloramphenicol acetyltransferase GO:0008811 CIG75_RS18030 ea1a75dfb3505a35d873f027f5983bbd 220 SMART SM01059 1 201 6.9E-88 T 28-03-2018 IPR001707 Chloramphenicol acetyltransferase GO:0008811 CIG75_RS05605 bcfcb53e010db1442d97705ff7927635 332 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS05605 bcfcb53e010db1442d97705ff7927635 332 SUPERFAMILY SSF52540 19 262 5.45E-74 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS05605 bcfcb53e010db1442d97705ff7927635 332 Pfam PF00005 ABC transporter 40 191 2.4E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS05605 bcfcb53e010db1442d97705ff7927635 332 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 242 329 2.7E-28 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CIG75_RS05605 bcfcb53e010db1442d97705ff7927635 332 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 243 310 4.5E-17 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CIG75_RS05605 bcfcb53e010db1442d97705ff7927635 332 SMART SM00382 49 241 1.5E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS05605 bcfcb53e010db1442d97705ff7927635 332 Gene3D G3DSA:3.40.50.300 16 332 1.9E-86 T 28-03-2018 CIG75_RS16630 f27ab0779e29eaf2560446108e84345b 77 Gene3D G3DSA:2.30.30.90 3 77 4.6E-19 T 28-03-2018 CIG75_RS16630 f27ab0779e29eaf2560446108e84345b 77 SUPERFAMILY SSF50037 8 76 1.53E-18 T 28-03-2018 IPR008988 Transcriptional repressor, C-terminal CIG75_RS16630 f27ab0779e29eaf2560446108e84345b 77 SMART SM00899 4 76 6.2E-20 T 28-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CIG75_RS16630 f27ab0779e29eaf2560446108e84345b 77 Pfam PF04023 FeoA domain 5 76 6.1E-17 T 28-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CIG75_RS19700 ab9d6177293634209bc2eba1807a95d7 144 PRINTS PR00060 Ribosomal protein L16 signature 88 117 1.3E-40 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS19700 ab9d6177293634209bc2eba1807a95d7 144 PRINTS PR00060 Ribosomal protein L16 signature 24 36 1.3E-40 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS19700 ab9d6177293634209bc2eba1807a95d7 144 PRINTS PR00060 Ribosomal protein L16 signature 58 87 1.3E-40 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS19700 ab9d6177293634209bc2eba1807a95d7 144 PRINTS PR00060 Ribosomal protein L16 signature 42 53 1.3E-40 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS19700 ab9d6177293634209bc2eba1807a95d7 144 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 28-03-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS19700 ab9d6177293634209bc2eba1807a95d7 144 SUPERFAMILY SSF54686 1 137 8.37E-58 T 28-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 CIG75_RS19700 ab9d6177293634209bc2eba1807a95d7 144 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 28-03-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS19700 ab9d6177293634209bc2eba1807a95d7 144 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 41.26 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS19700 ab9d6177293634209bc2eba1807a95d7 144 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 2.9E-51 T 28-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 CIG75_RS19700 ab9d6177293634209bc2eba1807a95d7 144 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 5.6E-62 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS19700 ab9d6177293634209bc2eba1807a95d7 144 Gene3D G3DSA:3.90.1170.10 3 139 3.5E-54 T 28-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 CIG75_RS07445 fc40e4427b8d99485db4c38f1b820830 506 Pfam PF13193 AMP-binding enzyme C-terminal domain 417 491 1.1E-21 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS07445 fc40e4427b8d99485db4c38f1b820830 506 ProSitePatterns PS00455 Putative AMP-binding domain signature. 163 174 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS07445 fc40e4427b8d99485db4c38f1b820830 506 Pfam PF00501 AMP-binding enzyme 8 408 9.6E-119 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS07445 fc40e4427b8d99485db4c38f1b820830 506 Gene3D G3DSA:3.30.300.30 401 502 1.2E-32 T 28-03-2018 CIG75_RS07445 fc40e4427b8d99485db4c38f1b820830 506 SUPERFAMILY SSF56801 5 503 1.31E-169 T 28-03-2018 CIG75_RS07445 fc40e4427b8d99485db4c38f1b820830 506 Gene3D G3DSA:2.30.38.10 320 400 2.2E-26 T 28-03-2018 CIG75_RS07445 fc40e4427b8d99485db4c38f1b820830 506 Gene3D G3DSA:3.40.50.980 169 319 3.0E-54 T 28-03-2018 CIG75_RS07445 fc40e4427b8d99485db4c38f1b820830 506 Gene3D G3DSA:3.40.50.980 2 168 4.1E-46 T 28-03-2018 CIG75_RS02155 2f51859585b09760816d8393f635f4de 455 Pfam PF01565 FAD binding domain 40 154 9.7E-20 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CIG75_RS02155 2f51859585b09760816d8393f635f4de 455 Gene3D G3DSA:3.30.465.10 62 187 3.7E-30 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CIG75_RS02155 2f51859585b09760816d8393f635f4de 455 Pfam PF04030 D-arabinono-1,4-lactone oxidase 389 447 1.8E-7 T 28-03-2018 IPR007173 D-arabinono-1,4-lactone oxidase GO:0003885|GO:0016020|GO:0055114 CIG75_RS02155 2f51859585b09760816d8393f635f4de 455 SUPERFAMILY SSF56176 12 185 2.38E-37 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CIG75_RS02155 2f51859585b09760816d8393f635f4de 455 SUPERFAMILY SSF55103 386 441 8.07E-5 T 28-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CIG75_RS03780 8de7297bd83b92e374018f68378ec94a 141 Pfam PF06713 Bacterial PH domain 63 135 1.0E-24 T 28-03-2018 IPR009589 Sublancin immunity protein SunI GO:0030153 CIG75_RS15995 ce3ea9aad3ffb23c1274a13efe1d1631 440 Gene3D G3DSA:3.30.830.10 18 237 2.5E-22 T 28-03-2018 CIG75_RS15995 ce3ea9aad3ffb23c1274a13efe1d1631 440 SUPERFAMILY SSF63411 18 243 1.1E-24 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CIG75_RS15995 ce3ea9aad3ffb23c1274a13efe1d1631 440 Pfam PF05193 Peptidase M16 inactive domain 196 370 1.9E-20 T 28-03-2018 IPR007863 Peptidase M16, C-terminal CIG75_RS15995 ce3ea9aad3ffb23c1274a13efe1d1631 440 SUPERFAMILY SSF63411 265 421 4.83E-28 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CIG75_RS15995 ce3ea9aad3ffb23c1274a13efe1d1631 440 Gene3D G3DSA:3.30.830.10 252 423 5.9E-27 T 28-03-2018 CIG75_RS09320 1b0a3ec0deab2d61db9d2d46b15a22f8 266 TIGRFAM TIGR02869 spore_SleB: spore cortex-lytic enzyme 40 266 2.7E-93 T 28-03-2018 IPR014224 Spore cortex-lytic enzyme SleB GO:0003824|GO:0009847 CIG75_RS09320 1b0a3ec0deab2d61db9d2d46b15a22f8 266 Pfam PF01471 Putative peptidoglycan binding domain 47 103 1.9E-17 T 28-03-2018 IPR002477 Peptidoglycan binding-like CIG75_RS09320 1b0a3ec0deab2d61db9d2d46b15a22f8 266 SUPERFAMILY SSF47090 37 104 1.05E-19 T 28-03-2018 IPR002477 Peptidoglycan binding-like CIG75_RS09320 1b0a3ec0deab2d61db9d2d46b15a22f8 266 Pfam PF07486 Cell Wall Hydrolase 167 265 2.3E-27 T 28-03-2018 IPR011105 Cell wall hydrolase, SleB GO:0016787 CIG75_RS09320 1b0a3ec0deab2d61db9d2d46b15a22f8 266 Gene3D G3DSA:1.10.101.10 33 109 1.9E-22 T 28-03-2018 IPR002477 Peptidoglycan binding-like CIG75_RS12920 ac90fa537311be0a7a8420c18c0d9657 347 Pfam PF13181 Tetratricopeptide repeat 271 302 0.033 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS12920 ac90fa537311be0a7a8420c18c0d9657 347 SUPERFAMILY SSF47413 78 142 1.35E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CIG75_RS12920 ac90fa537311be0a7a8420c18c0d9657 347 SMART SM00530 83 137 8.6E-15 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS12920 ac90fa537311be0a7a8420c18c0d9657 347 SMART SM00028 270 303 9.9 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS12920 ac90fa537311be0a7a8420c18c0d9657 347 SMART SM00028 190 223 10.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS12920 ac90fa537311be0a7a8420c18c0d9657 347 Gene3D G3DSA:1.25.40.10 188 339 1.1E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS12920 ac90fa537311be0a7a8420c18c0d9657 347 Gene3D G3DSA:1.10.3100.10 77 187 1.8E-21 T 28-03-2018 IPR027910 YdiL-like domain CIG75_RS12920 ac90fa537311be0a7a8420c18c0d9657 347 SUPERFAMILY SSF48452 155 305 1.9E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS12920 ac90fa537311be0a7a8420c18c0d9657 347 Pfam PF01381 Helix-turn-helix 84 137 6.1E-14 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS20165 c5581ae048a7244edcde51ee803d8e3f 205 SUPERFAMILY SSF63817 76 200 7.19E-23 T 28-03-2018 IPR023365 Sortase domain CIG75_RS20165 c5581ae048a7244edcde51ee803d8e3f 205 TIGRFAM TIGR01076 sortase_fam: sortase 80 197 1.1E-16 T 28-03-2018 IPR005754 Sortase family CIG75_RS20165 c5581ae048a7244edcde51ee803d8e3f 205 Gene3D G3DSA:2.40.260.10 44 203 2.0E-24 T 28-03-2018 IPR023365 Sortase domain CIG75_RS20165 c5581ae048a7244edcde51ee803d8e3f 205 Pfam PF04203 Sortase family 82 199 3.4E-20 T 28-03-2018 IPR005754 Sortase family CIG75_RS03325 e84ae3b2023ef0aa9d81e8549f2c4319 444 SUPERFAMILY SSF47413 4 67 8.04E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CIG75_RS03325 e84ae3b2023ef0aa9d81e8549f2c4319 444 Gene3D G3DSA:1.10.260.40 2 79 2.5E-19 T 28-03-2018 CIG75_RS03325 e84ae3b2023ef0aa9d81e8549f2c4319 444 Gene3D G3DSA:1.10.150.200 344 413 6.5E-8 T 28-03-2018 CIG75_RS03325 e84ae3b2023ef0aa9d81e8549f2c4319 444 SMART SM00028 115 148 140.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS03325 e84ae3b2023ef0aa9d81e8549f2c4319 444 SMART SM00028 155 188 29.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS03325 e84ae3b2023ef0aa9d81e8549f2c4319 444 SMART SM00028 236 269 0.31 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS03325 e84ae3b2023ef0aa9d81e8549f2c4319 444 SMART SM00028 276 309 19.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS03325 e84ae3b2023ef0aa9d81e8549f2c4319 444 SMART SM00028 406 439 0.093 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS03325 e84ae3b2023ef0aa9d81e8549f2c4319 444 SMART SM00028 366 399 280.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS03325 e84ae3b2023ef0aa9d81e8549f2c4319 444 SMART SM00028 196 229 45.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS03325 e84ae3b2023ef0aa9d81e8549f2c4319 444 Gene3D G3DSA:1.25.40.10 251 338 5.4E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS03325 e84ae3b2023ef0aa9d81e8549f2c4319 444 Gene3D G3DSA:1.25.40.10 209 250 1.2E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS03325 e84ae3b2023ef0aa9d81e8549f2c4319 444 Pfam PF01381 Helix-turn-helix 8 61 3.2E-15 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS03325 e84ae3b2023ef0aa9d81e8549f2c4319 444 SMART SM00530 7 61 2.6E-16 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS03325 e84ae3b2023ef0aa9d81e8549f2c4319 444 Gene3D G3DSA:1.25.40.10 80 208 1.4E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS03325 e84ae3b2023ef0aa9d81e8549f2c4319 444 SUPERFAMILY SSF48452 319 441 1.26E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS03325 e84ae3b2023ef0aa9d81e8549f2c4319 444 SUPERFAMILY SSF48452 119 306 1.71E-19 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS03325 e84ae3b2023ef0aa9d81e8549f2c4319 444 Gene3D G3DSA:1.25.40.10 414 444 4.6E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS03325 e84ae3b2023ef0aa9d81e8549f2c4319 444 Pfam PF13424 Tetratricopeptide repeat 238 308 8.0E-8 T 28-03-2018 CIG75_RS03325 e84ae3b2023ef0aa9d81e8549f2c4319 444 Pfam PF13424 Tetratricopeptide repeat 121 181 1.4E-8 T 28-03-2018 CIG75_RS03325 e84ae3b2023ef0aa9d81e8549f2c4319 444 Pfam PF13424 Tetratricopeptide repeat 369 435 1.2E-9 T 28-03-2018 CIG75_RS13820 7c722e4e1003e01fd908cec39dd28cc1 254 Pfam PF08769 Sporulation initiation factor Spo0A C terminal 144 247 4.2E-45 T 28-03-2018 IPR014879 Sporulation initiation factor Spo0A, C-terminal GO:0003700|GO:0005509|GO:0005737|GO:0006355|GO:0042173 CIG75_RS13820 7c722e4e1003e01fd908cec39dd28cc1 254 Gene3D G3DSA:3.40.50.2300 3 141 2.7E-34 T 28-03-2018 CIG75_RS13820 7c722e4e1003e01fd908cec39dd28cc1 254 SMART SM00448 4 119 1.0E-35 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CIG75_RS13820 7c722e4e1003e01fd908cec39dd28cc1 254 Pfam PF00072 Response regulator receiver domain 6 119 2.3E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CIG75_RS13820 7c722e4e1003e01fd908cec39dd28cc1 254 Gene3D G3DSA:1.10.10.10 142 250 9.6E-53 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS13820 7c722e4e1003e01fd908cec39dd28cc1 254 SUPERFAMILY SSF52172 2 134 1.85E-36 T 28-03-2018 IPR011006 CheY-like superfamily CIG75_RS13820 7c722e4e1003e01fd908cec39dd28cc1 254 TIGRFAM TIGR02875 spore_0_A: sporulation transcription factor Spo0A 3 254 7.3E-122 T 28-03-2018 IPR012052 Sporulation transcription factor Spo0A GO:0003677|GO:0005509|GO:0006355|GO:0043937|GO:0051606 CIG75_RS13820 7c722e4e1003e01fd908cec39dd28cc1 254 PIRSF PIRSF002937 1 254 3.4E-121 T 28-03-2018 IPR012052 Sporulation transcription factor Spo0A GO:0003677|GO:0005509|GO:0006355|GO:0043937|GO:0051606 CIG75_RS13820 7c722e4e1003e01fd908cec39dd28cc1 254 ProDom PD010908 TRANSCRIPTION SPORULATION TWO-COMPONENT DNA-BINDING PHOSPHORYLATION SENSORY REGULATION TRANSDUCTION METAL-BINDING CALCIUM 143 252 2.0E-49 T 28-03-2018 IPR014879 Sporulation initiation factor Spo0A, C-terminal GO:0003700|GO:0005509|GO:0005737|GO:0006355|GO:0042173 CIG75_RS13820 7c722e4e1003e01fd908cec39dd28cc1 254 SUPERFAMILY SSF46894 138 251 1.11E-46 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CIG75_RS11785 56e11dfb65c52e0c5cbd8346addd1c68 305 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 2 214 1.4E-71 T 28-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 CIG75_RS11785 56e11dfb65c52e0c5cbd8346addd1c68 305 Gene3D G3DSA:3.30.2350.10 1 226 7.0E-83 T 28-03-2018 CIG75_RS11785 56e11dfb65c52e0c5cbd8346addd1c68 305 SUPERFAMILY SSF55120 1 235 3.2E-80 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CIG75_RS11785 56e11dfb65c52e0c5cbd8346addd1c68 305 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 2 303 19.562 T 28-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 CIG75_RS11785 56e11dfb65c52e0c5cbd8346addd1c68 305 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 24 176 1.6E-54 T 28-03-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 CIG75_RS11785 56e11dfb65c52e0c5cbd8346addd1c68 305 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 177 235 2.0E-17 T 28-03-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 CIG75_RS04785 11f511057e4626f5f9a03bb640e6abd9 231 SMART SM00862 153 229 4.4E-23 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CIG75_RS04785 11f511057e4626f5f9a03bb640e6abd9 231 SUPERFAMILY SSF52172 1 187 5.89E-43 T 28-03-2018 IPR011006 CheY-like superfamily CIG75_RS04785 11f511057e4626f5f9a03bb640e6abd9 231 Pfam PF00486 Transcriptional regulatory protein, C terminal 155 229 1.2E-26 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CIG75_RS04785 11f511057e4626f5f9a03bb640e6abd9 231 Pfam PF00072 Response regulator receiver domain 6 115 1.2E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CIG75_RS04785 11f511057e4626f5f9a03bb640e6abd9 231 SMART SM00448 4 114 2.6E-44 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CIG75_RS04785 11f511057e4626f5f9a03bb640e6abd9 231 Gene3D G3DSA:1.10.10.10 129 231 3.4E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS04785 11f511057e4626f5f9a03bb640e6abd9 231 Gene3D G3DSA:3.40.50.2300 1 128 2.0E-37 T 28-03-2018 CIG75_RS18740 21c3a2572cb54377588371ac031ef239 543 PRINTS PR00298 60kDa chaperonin signature 396 417 1.3E-73 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CIG75_RS18740 21c3a2572cb54377588371ac031ef239 543 PRINTS PR00298 60kDa chaperonin signature 266 289 1.3E-73 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CIG75_RS18740 21c3a2572cb54377588371ac031ef239 543 PRINTS PR00298 60kDa chaperonin signature 82 109 1.3E-73 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CIG75_RS18740 21c3a2572cb54377588371ac031ef239 543 PRINTS PR00298 60kDa chaperonin signature 26 52 1.3E-73 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CIG75_RS18740 21c3a2572cb54377588371ac031ef239 543 PRINTS PR00298 60kDa chaperonin signature 348 373 1.3E-73 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CIG75_RS18740 21c3a2572cb54377588371ac031ef239 543 Gene3D G3DSA:1.10.560.10 1 189 1.0E-34 T 28-03-2018 IPR027413 GroEL-like equatorial domain CIG75_RS18740 21c3a2572cb54377588371ac031ef239 543 SUPERFAMILY SSF48592 6 133 4.58E-79 T 28-03-2018 CIG75_RS18740 21c3a2572cb54377588371ac031ef239 543 SUPERFAMILY SSF48592 404 518 4.58E-79 T 28-03-2018 CIG75_RS18740 21c3a2572cb54377588371ac031ef239 543 Gene3D G3DSA:1.10.560.10 372 513 2.7E-27 T 28-03-2018 IPR027413 GroEL-like equatorial domain CIG75_RS18740 21c3a2572cb54377588371ac031ef239 543 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 522 6.3E-99 T 28-03-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 CIG75_RS18740 21c3a2572cb54377588371ac031ef239 543 Gene3D G3DSA:3.50.7.10 190 371 2.8E-95 T 28-03-2018 IPR027409 GroEL-like apical domain CIG75_RS18740 21c3a2572cb54377588371ac031ef239 543 SUPERFAMILY SSF52029 183 374 2.09E-82 T 28-03-2018 IPR027409 GroEL-like apical domain CIG75_RS18740 21c3a2572cb54377588371ac031ef239 543 ProSitePatterns PS00296 Chaperonins cpn60 signature. 403 414 - T 28-03-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CIG75_RS18740 21c3a2572cb54377588371ac031ef239 543 Hamap MF_00600 60 kDa chaperonin [groL]. 1 540 42.378 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CIG75_RS18740 21c3a2572cb54377588371ac031ef239 543 SUPERFAMILY SSF54849 136 202 5.72E-26 T 28-03-2018 CIG75_RS18740 21c3a2572cb54377588371ac031ef239 543 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 523 8.8E-257 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CIG75_RS16405 1751b093a2a04bd896081a3eb56847b3 229 Gene3D G3DSA:1.10.287.540 111 132 2.4E-9 T 28-03-2018 CIG75_RS16405 1751b093a2a04bd896081a3eb56847b3 229 Gene3D G3DSA:1.10.287.540 173 209 3.5E-9 T 28-03-2018 CIG75_RS16405 1751b093a2a04bd896081a3eb56847b3 229 Gene3D G3DSA:1.10.287.540 133 154 1.7E-9 T 28-03-2018 CIG75_RS16405 1751b093a2a04bd896081a3eb56847b3 229 Pfam PF13870 Domain of unknown function (DUF4201) 79 177 8.6E-7 T 28-03-2018 IPR025254 Domain of unknown function DUF4201 CIG75_RS16405 1751b093a2a04bd896081a3eb56847b3 229 SUPERFAMILY SSF58104 42 220 1.7E-7 T 28-03-2018 CIG75_RS16405 1751b093a2a04bd896081a3eb56847b3 229 Gene3D G3DSA:1.20.58.130 24 86 1.3E-10 T 28-03-2018 CIG75_RS16405 1751b093a2a04bd896081a3eb56847b3 229 Gene3D G3DSA:1.20.5.170 155 172 9.9E-4 T 28-03-2018 CIG75_RS16405 1751b093a2a04bd896081a3eb56847b3 229 Pfam PF05701 Weak chloroplast movement under blue light 21 219 1.4E-8 T 28-03-2018 IPR008545 WEB family CIG75_RS16405 1751b093a2a04bd896081a3eb56847b3 229 Gene3D G3DSA:1.20.5.190 87 110 9.0E-5 T 28-03-2018 CIG75_RS10495 7fb266bef1e6af807f1d25c6b1accce4 438 PRINTS PR00723 Subtilisin serine protease family (S8) signature 135 154 1.6E-19 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CIG75_RS10495 7fb266bef1e6af807f1d25c6b1accce4 438 PRINTS PR00723 Subtilisin serine protease family (S8) signature 376 392 1.6E-19 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CIG75_RS10495 7fb266bef1e6af807f1d25c6b1accce4 438 PRINTS PR00723 Subtilisin serine protease family (S8) signature 173 186 1.6E-19 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CIG75_RS10495 7fb266bef1e6af807f1d25c6b1accce4 438 Pfam PF00082 Subtilase family 135 429 5.1E-44 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CIG75_RS10495 7fb266bef1e6af807f1d25c6b1accce4 438 SUPERFAMILY SSF52743 132 437 5.37E-70 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CIG75_RS10495 7fb266bef1e6af807f1d25c6b1accce4 438 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 177 187 - T 28-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site CIG75_RS10495 7fb266bef1e6af807f1d25c6b1accce4 438 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 140 151 - T 28-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site CIG75_RS10495 7fb266bef1e6af807f1d25c6b1accce4 438 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 377 387 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CIG75_RS10495 7fb266bef1e6af807f1d25c6b1accce4 438 Gene3D G3DSA:3.40.50.200 83 438 2.0E-73 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CIG75_RS13500 83a1d2a36e1241ef187e8ac249d1eb64 320 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 5 319 23.976 T 28-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CIG75_RS13500 83a1d2a36e1241ef187e8ac249d1eb64 320 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 18 316 7.1E-116 T 28-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CIG75_RS13500 83a1d2a36e1241ef187e8ac249d1eb64 320 ProSitePatterns PS01348 MraY family signature 2. 165 176 - T 28-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CIG75_RS13500 83a1d2a36e1241ef187e8ac249d1eb64 320 ProSitePatterns PS01347 MraY family signature 1. 48 60 - T 28-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CIG75_RS13500 83a1d2a36e1241ef187e8ac249d1eb64 320 Pfam PF00953 Glycosyl transferase family 4 78 245 2.8E-40 T 28-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CIG75_RS13500 83a1d2a36e1241ef187e8ac249d1eb64 320 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 48 60 4.3E-6 T 28-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CIG75_RS02375 969664d5255a88cd745b912957c2475b 281 PRINTS PR00207 Flagellin signature 35 52 2.3E-25 T 28-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 CIG75_RS02375 969664d5255a88cd745b912957c2475b 281 PRINTS PR00207 Flagellin signature 74 93 2.3E-25 T 28-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 CIG75_RS02375 969664d5255a88cd745b912957c2475b 281 PRINTS PR00207 Flagellin signature 109 132 2.3E-25 T 28-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 CIG75_RS02375 969664d5255a88cd745b912957c2475b 281 Gene3D G3DSA:1.20.1330.10 38 253 7.2E-79 T 28-03-2018 CIG75_RS02375 969664d5255a88cd745b912957c2475b 281 SUPERFAMILY SSF64518 1 281 3.14E-97 T 28-03-2018 CIG75_RS02375 969664d5255a88cd745b912957c2475b 281 Pfam PF00700 Bacterial flagellin C-terminal helical region 195 280 5.0E-32 T 28-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 CIG75_RS02375 969664d5255a88cd745b912957c2475b 281 Pfam PF00669 Bacterial flagellin N-terminal helical region 3 139 2.6E-44 T 28-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 CIG75_RS11475 fa63698d8517a0845e0a92eafd7e6452 444 Gene3D G3DSA:3.40.50.20 87 193 5.8E-4 T 28-03-2018 CIG75_RS11475 fa63698d8517a0845e0a92eafd7e6452 444 Pfam PF14398 YheC/D like ATP-grasp 185 438 1.0E-73 T 28-03-2018 IPR026838 Endospore coat-associated protein YheC/D CIG75_RS11475 fa63698d8517a0845e0a92eafd7e6452 444 Gene3D G3DSA:3.30.470.20 287 421 5.7E-11 T 28-03-2018 CIG75_RS11475 fa63698d8517a0845e0a92eafd7e6452 444 Gene3D G3DSA:3.30.1490.20 216 286 1.6E-7 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CIG75_RS11475 fa63698d8517a0845e0a92eafd7e6452 444 SUPERFAMILY SSF56059 211 413 6.01E-11 T 28-03-2018 CIG75_RS07530 e7923de49399004f70288c7144f0e70c 585 ProSitePatterns PS00211 ABC transporters family signature. 477 491 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS07530 e7923de49399004f70288c7144f0e70c 585 Gene3D G3DSA:1.20.1560.10 1 324 4.9E-66 T 28-03-2018 CIG75_RS07530 e7923de49399004f70288c7144f0e70c 585 SUPERFAMILY SSF90123 7 323 4.45E-77 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CIG75_RS07530 e7923de49399004f70288c7144f0e70c 585 SUPERFAMILY SSF52540 331 576 3.3E-88 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS07530 e7923de49399004f70288c7144f0e70c 585 Gene3D G3DSA:3.40.50.300 325 581 2.5E-74 T 28-03-2018 CIG75_RS07530 e7923de49399004f70288c7144f0e70c 585 Pfam PF00664 ABC transporter transmembrane region 19 291 6.4E-49 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CIG75_RS07530 e7923de49399004f70288c7144f0e70c 585 Pfam PF00005 ABC transporter 354 503 1.0E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS07530 e7923de49399004f70288c7144f0e70c 585 SMART SM00382 363 557 2.7E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS07040 98a7d31c5d35376b7b1fa42817cb52f0 373 Gene3D G3DSA:3.40.50.300 58 228 3.6E-28 T 28-03-2018 CIG75_RS07040 98a7d31c5d35376b7b1fa42817cb52f0 373 Pfam PF01926 50S ribosome-binding GTPase 165 226 3.2E-11 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CIG75_RS07040 98a7d31c5d35376b7b1fa42817cb52f0 373 TIGRFAM TIGR03597 GTPase_YqeH: ribosome biogenesis GTPase YqeH 8 373 9.3E-125 T 28-03-2018 IPR019988 GTP-binding protein, riobosome biogenesis, YqeH CIG75_RS07040 98a7d31c5d35376b7b1fa42817cb52f0 373 SUPERFAMILY SSF52540 65 282 1.85E-27 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS03385 4aa4b5e8bd43fdf3d7536f424a5fe390 584 SUPERFAMILY SSF90123 20 322 4.19E-54 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CIG75_RS03385 4aa4b5e8bd43fdf3d7536f424a5fe390 584 SUPERFAMILY SSF52540 341 575 1.25E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS03385 4aa4b5e8bd43fdf3d7536f424a5fe390 584 Gene3D G3DSA:1.20.1560.10 6 331 1.1E-50 T 28-03-2018 CIG75_RS03385 4aa4b5e8bd43fdf3d7536f424a5fe390 584 Pfam PF00005 ABC transporter 359 505 2.9E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS03385 4aa4b5e8bd43fdf3d7536f424a5fe390 584 SMART SM00382 367 560 2.4E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS03385 4aa4b5e8bd43fdf3d7536f424a5fe390 584 Pfam PF00664 ABC transporter transmembrane region 34 298 8.7E-24 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CIG75_RS03385 4aa4b5e8bd43fdf3d7536f424a5fe390 584 ProSitePatterns PS00211 ABC transporters family signature. 478 492 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS03385 4aa4b5e8bd43fdf3d7536f424a5fe390 584 Gene3D G3DSA:3.40.50.300 342 583 1.3E-58 T 28-03-2018 CIG75_RS04875 f1883dd0390d26bdca1fa99623a81ed9 165 Gene3D G3DSA:3.40.630.30 2 165 1.5E-21 T 28-03-2018 CIG75_RS04875 f1883dd0390d26bdca1fa99623a81ed9 165 SUPERFAMILY SSF55729 5 147 1.64E-26 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CIG75_RS04875 f1883dd0390d26bdca1fa99623a81ed9 165 Pfam PF13302 Acetyltransferase (GNAT) domain 9 138 4.4E-20 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CIG75_RS15090 f23ea31c126e40c7eb714a2f9d542862 588 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 475 551 9.0E-13 T 28-03-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II CIG75_RS15090 f23ea31c126e40c7eb714a2f9d542862 588 Gene3D G3DSA:3.40.920.10 2 183 3.3E-39 T 28-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CIG75_RS15090 f23ea31c126e40c7eb714a2f9d542862 588 SUPERFAMILY SSF53323 7 218 7.85E-38 T 28-03-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 CIG75_RS15090 f23ea31c126e40c7eb714a2f9d542862 588 SUPERFAMILY SSF52518 197 458 7.36E-65 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CIG75_RS15090 f23ea31c126e40c7eb714a2f9d542862 588 Gene3D G3DSA:3.40.50.920 470 581 3.2E-17 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CIG75_RS15090 f23ea31c126e40c7eb714a2f9d542862 588 SUPERFAMILY SSF52922 469 587 7.85E-23 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CIG75_RS15090 f23ea31c126e40c7eb714a2f9d542862 588 Gene3D G3DSA:3.40.50.970 195 469 3.1E-55 T 28-03-2018 CIG75_RS15090 f23ea31c126e40c7eb714a2f9d542862 588 TIGRFAM TIGR03710 OAFO_sf: 2-oxoacid:acceptor oxidoreductase, alpha subunit 5 574 3.1E-196 T 28-03-2018 IPR022367 2-oxoacid:acceptor oxidoreductase, alpha subunit KEGG: 00020+1.2.7.3|KEGG: 00720+1.2.7.3|MetaCyc: PWY-5392|MetaCyc: PWY-6969 CIG75_RS15090 f23ea31c126e40c7eb714a2f9d542862 588 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 210 452 3.3E-61 T 28-03-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 CIG75_RS15090 f23ea31c126e40c7eb714a2f9d542862 588 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 14 176 2.3E-37 T 28-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CIG75_RS08685 3f2ed76f99b50be2014aa76307815ab4 184 Pfam PF00578 AhpC/TSA family 48 164 6.3E-29 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CIG75_RS08685 3f2ed76f99b50be2014aa76307815ab4 184 ProSitePatterns PS00194 Thioredoxin family active site. 75 93 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 CIG75_RS08685 3f2ed76f99b50be2014aa76307815ab4 184 SUPERFAMILY SSF52833 44 183 1.06E-43 T 28-03-2018 IPR012336 Thioredoxin-like fold CIG75_RS08685 3f2ed76f99b50be2014aa76307815ab4 184 Gene3D G3DSA:3.40.30.10 33 184 6.1E-40 T 28-03-2018 CIG75_RS12335 ec234486fab569ef679f2affd13bc528 1190 SUPERFAMILY SSF57997 763 1007 5.89E-7 T 28-03-2018 CIG75_RS12335 ec234486fab569ef679f2affd13bc528 1190 SUPERFAMILY SSF75553 483 689 1.83E-47 T 28-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 CIG75_RS12335 ec234486fab569ef679f2affd13bc528 1190 Gene3D G3DSA:1.20.120.330 830 957 3.8E-6 T 28-03-2018 CIG75_RS12335 ec234486fab569ef679f2affd13bc528 1190 SMART SM00968 522 641 1.7E-36 T 28-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 CIG75_RS12335 ec234486fab569ef679f2affd13bc528 1190 Gene3D G3DSA:3.40.50.300 958 1188 5.1E-30 T 28-03-2018 CIG75_RS12335 ec234486fab569ef679f2affd13bc528 1190 SUPERFAMILY SSF52540 2 207 4.63E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS12335 ec234486fab569ef679f2affd13bc528 1190 SUPERFAMILY SSF52540 980 1177 4.63E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS12335 ec234486fab569ef679f2affd13bc528 1190 Gene3D G3DSA:1.20.5.340 368 499 0.29 T 28-03-2018 CIG75_RS12335 ec234486fab569ef679f2affd13bc528 1190 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1184 24.073 T 28-03-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 CIG75_RS12335 ec234486fab569ef679f2affd13bc528 1190 Gene3D G3DSA:1.20.1170.10 650 745 5.2E-5 T 28-03-2018 CIG75_RS12335 ec234486fab569ef679f2affd13bc528 1190 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 1175 8.3E-79 T 28-03-2018 IPR003395 RecF/RecN/SMC, N-terminal CIG75_RS12335 ec234486fab569ef679f2affd13bc528 1190 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 2 1182 0.0 T 28-03-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 CIG75_RS12335 ec234486fab569ef679f2affd13bc528 1190 Gene3D G3DSA:1.20.5.50 746 829 0.0013 T 28-03-2018 CIG75_RS12335 ec234486fab569ef679f2affd13bc528 1190 PIRSF PIRSF005719 1 1189 0.0 T 28-03-2018 IPR024704 Structural maintenance of chromosomes protein CIG75_RS12335 ec234486fab569ef679f2affd13bc528 1190 Gene3D G3DSA:3.40.50.300 1 180 9.3E-40 T 28-03-2018 CIG75_RS12335 ec234486fab569ef679f2affd13bc528 1190 Pfam PF06470 SMC proteins Flexible Hinge Domain 522 641 1.2E-25 T 28-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 CIG75_RS02275 ef40fb5654b46d662f2fe403d43e9aa9 230 SUPERFAMILY SSF52172 1 122 2.13E-42 T 28-03-2018 IPR011006 CheY-like superfamily CIG75_RS02275 ef40fb5654b46d662f2fe403d43e9aa9 230 Gene3D G3DSA:1.10.10.10 123 230 6.4E-38 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS02275 ef40fb5654b46d662f2fe403d43e9aa9 230 SMART SM00862 150 226 1.5E-34 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CIG75_RS02275 ef40fb5654b46d662f2fe403d43e9aa9 230 SMART SM00448 2 114 3.7E-47 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CIG75_RS02275 ef40fb5654b46d662f2fe403d43e9aa9 230 SUPERFAMILY SSF46894 126 227 2.04E-35 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CIG75_RS02275 ef40fb5654b46d662f2fe403d43e9aa9 230 Gene3D G3DSA:3.40.50.2300 1 122 9.6E-38 T 28-03-2018 CIG75_RS02275 ef40fb5654b46d662f2fe403d43e9aa9 230 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 226 1.7E-32 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CIG75_RS02275 ef40fb5654b46d662f2fe403d43e9aa9 230 Pfam PF00072 Response regulator receiver domain 4 115 3.7E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CIG75_RS05820 15b15178194aa1f3dbf31218c1c4565b 259 Gene3D G3DSA:3.60.160.10 1 249 1.5E-78 T 28-03-2018 IPR002838 Mitochondrial biogenesis protein AIM24 CIG75_RS05820 15b15178194aa1f3dbf31218c1c4565b 259 TIGRFAM TIGR00266 TIGR00266: TIGR00266 family protein 8 226 2.8E-33 T 28-03-2018 IPR002838 Mitochondrial biogenesis protein AIM24 CIG75_RS05820 15b15178194aa1f3dbf31218c1c4565b 259 SUPERFAMILY SSF51219 6 241 3.14E-84 T 28-03-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain CIG75_RS05820 15b15178194aa1f3dbf31218c1c4565b 259 Pfam PF01987 Mitochondrial biogenesis AIM24 8 225 4.7E-68 T 28-03-2018 IPR002838 Mitochondrial biogenesis protein AIM24 CIG75_RS01175 0d32f8434645f040123208b5fddf5169 145 Pfam PF00583 Acetyltransferase (GNAT) family 33 133 6.3E-17 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CIG75_RS01175 0d32f8434645f040123208b5fddf5169 145 SUPERFAMILY SSF55729 1 136 2.03E-30 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CIG75_RS01175 0d32f8434645f040123208b5fddf5169 145 Gene3D G3DSA:3.40.630.30 1 83 3.1E-14 T 28-03-2018 CIG75_RS01175 0d32f8434645f040123208b5fddf5169 145 Gene3D G3DSA:3.40.630.30 84 136 4.1E-12 T 28-03-2018 CIG75_RS18210 304ca3c9126238cd68c349dab5f2a103 347 Pfam PF12840 Helix-turn-helix domain 269 322 1.3E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS18210 304ca3c9126238cd68c349dab5f2a103 347 SUPERFAMILY SSF46785 263 342 1.57E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS18210 304ca3c9126238cd68c349dab5f2a103 347 SMART SM00418 267 341 6.8E-6 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CIG75_RS18210 304ca3c9126238cd68c349dab5f2a103 347 Gene3D G3DSA:1.10.10.10 260 334 8.8E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS03805 1659e58c098f28888403b9f2fa6dc226 303 Pfam PF02310 B12 binding domain 179 269 4.7E-11 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CIG75_RS03805 1659e58c098f28888403b9f2fa6dc226 303 Gene3D G3DSA:3.40.50.280 172 297 5.3E-17 T 28-03-2018 CIG75_RS03805 1659e58c098f28888403b9f2fa6dc226 303 Pfam PF02607 B12 binding domain 96 162 2.3E-8 T 28-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CIG75_RS03805 1659e58c098f28888403b9f2fa6dc226 303 SMART SM00422 2 72 1.0E-15 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CIG75_RS03805 1659e58c098f28888403b9f2fa6dc226 303 SUPERFAMILY SSF46955 1 75 4.44E-15 T 28-03-2018 IPR009061 Putative DNA-binding domain CIG75_RS03805 1659e58c098f28888403b9f2fa6dc226 303 Pfam PF13411 MerR HTH family regulatory protein 2 70 5.8E-15 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CIG75_RS03805 1659e58c098f28888403b9f2fa6dc226 303 Gene3D G3DSA:1.10.1660.10 1 107 3.3E-18 T 28-03-2018 CIG75_RS03805 1659e58c098f28888403b9f2fa6dc226 303 SUPERFAMILY SSF52242 176 288 1.24E-15 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CIG75_RS10605 e6a1db298289f2a018942599eec9a537 426 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 3 288 2.2E-98 T 28-03-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 CIG75_RS10605 e6a1db298289f2a018942599eec9a537 426 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 7 323 1.2E-41 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CIG75_RS10605 e6a1db298289f2a018942599eec9a537 426 SUPERFAMILY SSF55048 130 197 1.44E-12 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CIG75_RS10605 e6a1db298289f2a018942599eec9a537 426 Gene3D G3DSA:3.40.366.10 175 306 1.2E-24 T 28-03-2018 CIG75_RS10605 e6a1db298289f2a018942599eec9a537 426 Gene3D G3DSA:3.40.366.10 1 174 2.1E-52 T 28-03-2018 CIG75_RS10605 e6a1db298289f2a018942599eec9a537 426 Pfam PF00698 Acyl transferase domain 6 281 7.3E-36 T 28-03-2018 IPR014043 Acyl transferase CIG75_RS10605 e6a1db298289f2a018942599eec9a537 426 SUPERFAMILY SSF52151 3 128 3.92E-74 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CIG75_RS10605 e6a1db298289f2a018942599eec9a537 426 SUPERFAMILY SSF52151 198 298 3.92E-74 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CIG75_RS14780 1dbe76d8328809ccb1fab8ad18d1387d 313 Pfam PF02690 Na+/Pi-cotransporter 16 149 1.5E-35 T 28-03-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 CIG75_RS14780 1dbe76d8328809ccb1fab8ad18d1387d 313 Pfam PF02690 Na+/Pi-cotransporter 147 253 2.5E-19 T 28-03-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 CIG75_RS14780 1dbe76d8328809ccb1fab8ad18d1387d 313 TIGRFAM TIGR00704 NaPi_cotrn_rel: Na/Pi-cotransporter II-related protein 7 309 1.7E-74 T 28-03-2018 IPR004633 Na/Pi-cotransporter II-related/YqeW-like protein GO:0016020 CIG75_RS18080 bc879e8d361c5ffe919c41ea807c1fc4 345 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 10 334 7.1E-143 T 28-03-2018 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 CIG75_RS18080 bc879e8d361c5ffe919c41ea807c1fc4 345 Gene3D G3DSA:3.40.50.970 2 342 1.3E-96 T 28-03-2018 CIG75_RS18080 bc879e8d361c5ffe919c41ea807c1fc4 345 Pfam PF00676 Dehydrogenase E1 component 25 308 2.2E-91 T 28-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 CIG75_RS18080 bc879e8d361c5ffe919c41ea807c1fc4 345 SUPERFAMILY SSF52518 11 336 4.42E-110 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CIG75_RS10365 385755ab08d889df1295723a4df44ac0 119 SUPERFAMILY SSF54593 4 118 2.15E-21 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CIG75_RS10365 385755ab08d889df1295723a4df44ac0 119 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 10 114 1.4E-6 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CIG75_RS10365 385755ab08d889df1295723a4df44ac0 119 Gene3D G3DSA:3.10.180.10 2 119 2.4E-18 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CIG75_RS09990 76340d675a7070a58b41f97c500b7461 500 SUPERFAMILY SSF52540 61 313 9.29E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS09990 76340d675a7070a58b41f97c500b7461 500 SUPERFAMILY SSF140990 326 490 1.83E-41 T 28-03-2018 CIG75_RS09990 76340d675a7070a58b41f97c500b7461 500 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 104 242 5.0E-41 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CIG75_RS09990 76340d675a7070a58b41f97c500b7461 500 ProSitePatterns PS00674 AAA-protein family signature. 213 231 - T 28-03-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 CIG75_RS09990 76340d675a7070a58b41f97c500b7461 500 Gene3D G3DSA:1.10.8.60 251 315 8.6E-22 T 28-03-2018 CIG75_RS09990 76340d675a7070a58b41f97c500b7461 500 SMART SM00382 100 245 1.5E-21 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS09990 76340d675a7070a58b41f97c500b7461 500 Pfam PF01434 Peptidase family M41 305 487 6.1E-37 T 28-03-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 CIG75_RS09990 76340d675a7070a58b41f97c500b7461 500 Gene3D G3DSA:3.40.50.300 55 250 1.1E-55 T 28-03-2018 CIG75_RS11025 3e938251acbcb8a709f9d0e04a22221f 438 Pfam PF13424 Tetratricopeptide repeat 154 228 1.5E-10 T 28-03-2018 CIG75_RS11025 3e938251acbcb8a709f9d0e04a22221f 438 SMART SM00530 12 66 1.9E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS11025 3e938251acbcb8a709f9d0e04a22221f 438 SUPERFAMILY SSF48452 193 411 6.32E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS11025 3e938251acbcb8a709f9d0e04a22221f 438 Gene3D G3DSA:1.25.40.10 250 309 0.31 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS11025 3e938251acbcb8a709f9d0e04a22221f 438 Pfam PF01381 Helix-turn-helix 13 66 4.1E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS11025 3e938251acbcb8a709f9d0e04a22221f 438 Gene3D G3DSA:1.25.40.10 310 437 2.2E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS11025 3e938251acbcb8a709f9d0e04a22221f 438 Gene3D G3DSA:1.25.40.10 73 171 1.0E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS11025 3e938251acbcb8a709f9d0e04a22221f 438 SMART SM00028 237 270 140.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS11025 3e938251acbcb8a709f9d0e04a22221f 438 SMART SM00028 156 189 2.9 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS11025 3e938251acbcb8a709f9d0e04a22221f 438 SMART SM00028 317 350 72.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS11025 3e938251acbcb8a709f9d0e04a22221f 438 SMART SM00028 197 230 37.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS11025 3e938251acbcb8a709f9d0e04a22221f 438 Gene3D G3DSA:1.10.260.40 2 72 1.6E-18 T 28-03-2018 CIG75_RS11025 3e938251acbcb8a709f9d0e04a22221f 438 SUPERFAMILY SSF48452 113 235 5.06E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS11025 3e938251acbcb8a709f9d0e04a22221f 438 Gene3D G3DSA:1.25.40.10 172 249 2.1E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS11025 3e938251acbcb8a709f9d0e04a22221f 438 SUPERFAMILY SSF47413 5 70 1.49E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CIG75_RS04595 b0c0b69e968538fa606d53dfa43688e3 302 Gene3D G3DSA:3.60.15.10 25 278 2.6E-31 T 28-03-2018 IPR001279 Metallo-beta-lactamase CIG75_RS04595 b0c0b69e968538fa606d53dfa43688e3 302 Pfam PF00753 Metallo-beta-lactamase superfamily 51 250 1.2E-15 T 28-03-2018 IPR001279 Metallo-beta-lactamase CIG75_RS04595 b0c0b69e968538fa606d53dfa43688e3 302 SMART SM00849 54 253 4.0E-7 T 28-03-2018 IPR001279 Metallo-beta-lactamase CIG75_RS04595 b0c0b69e968538fa606d53dfa43688e3 302 SUPERFAMILY SSF56281 45 295 2.57E-51 T 28-03-2018 IPR001279 Metallo-beta-lactamase CIG75_RS14500 4324f3312945a4bc1e748d2a058e721c 462 Pfam PF13636 RNA-binding PUA-like domain of methyltransferase RsmF 415 461 5.9E-22 T 28-03-2018 IPR027391 rRNA small subunit methyltransferase F, RNA-binding PUA-like domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CIG75_RS14500 4324f3312945a4bc1e748d2a058e721c 462 Gene3D G3DSA:3.40.50.150 94 319 2.6E-59 T 28-03-2018 CIG75_RS14500 4324f3312945a4bc1e748d2a058e721c 462 Pfam PF01189 16S rRNA methyltransferase RsmB/F 102 307 2.5E-53 T 28-03-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CIG75_RS14500 4324f3312945a4bc1e748d2a058e721c 462 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 179 190 - T 28-03-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CIG75_RS14500 4324f3312945a4bc1e748d2a058e721c 462 Gene3D G3DSA:3.30.70.1170 30 93 1.5E-21 T 28-03-2018 CIG75_RS14500 4324f3312945a4bc1e748d2a058e721c 462 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 291 308 8.6E-27 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CIG75_RS14500 4324f3312945a4bc1e748d2a058e721c 462 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 180 192 8.6E-27 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CIG75_RS14500 4324f3312945a4bc1e748d2a058e721c 462 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 230 246 8.6E-27 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CIG75_RS14500 4324f3312945a4bc1e748d2a058e721c 462 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 113 123 8.6E-27 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CIG75_RS14500 4324f3312945a4bc1e748d2a058e721c 462 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 84 98 8.6E-27 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CIG75_RS14500 4324f3312945a4bc1e748d2a058e721c 462 Pfam PF17126 RsmF rRNA methyltransferase first C-terminal domain 335 396 3.8E-27 T 28-03-2018 IPR031340 Ribosomal RNA small subunit methyltransferase F, first C-terminal domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CIG75_RS14500 4324f3312945a4bc1e748d2a058e721c 462 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 11 98 4.3E-33 T 28-03-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 CIG75_RS14500 4324f3312945a4bc1e748d2a058e721c 462 SUPERFAMILY SSF53335 8 308 9.45E-65 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CIG75_RS14500 4324f3312945a4bc1e748d2a058e721c 462 TIGRFAM TIGR00446 nop2p: NOL1/NOP2/sun family putative RNA methylase 41 308 1.2E-67 T 28-03-2018 IPR011023 Nop2p GO:0003723|GO:0006364|GO:0008757 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 CIG75_RS15390 34acec8b47a622bfcc28e11118262ad6 286 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 47 194 1.6E-31 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CIG75_RS15390 34acec8b47a622bfcc28e11118262ad6 286 Gene3D G3DSA:3.40.50.970 72 284 8.9E-51 T 28-03-2018 CIG75_RS15390 34acec8b47a622bfcc28e11118262ad6 286 Gene3D G3DSA:3.40.50.970 4 71 8.2E-14 T 28-03-2018 CIG75_RS15390 34acec8b47a622bfcc28e11118262ad6 286 SUPERFAMILY SSF52518 11 257 1.84E-74 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CIG75_RS15390 34acec8b47a622bfcc28e11118262ad6 286 TIGRFAM TIGR02177 PorB_KorB: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family 13 258 2.4E-94 T 28-03-2018 IPR011896 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate CIG75_RS15390 34acec8b47a622bfcc28e11118262ad6 286 Pfam PF12367 Pyruvate ferredoxin oxidoreductase beta subunit C terminal 198 257 9.4E-21 T 28-03-2018 IPR032686 Pyruvate ferredoxin oxidoreductase beta subunit, C-terminal CIG75_RS07020 1505265a88e73aabb421c7a8a6ee347b 406 Gene3D G3DSA:3.40.50.1100 91 199 2.4E-16 T 28-03-2018 CIG75_RS07020 1505265a88e73aabb421c7a8a6ee347b 406 SUPERFAMILY SSF53686 5 390 2.23E-79 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CIG75_RS07020 1505265a88e73aabb421c7a8a6ee347b 406 Gene3D G3DSA:3.40.50.1100 200 393 3.8E-32 T 28-03-2018 CIG75_RS07020 1505265a88e73aabb421c7a8a6ee347b 406 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 77 381 5.5E-60 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CIG75_RS08285 f460a3f6a6345aaa161840b95294225c 185 Pfam PF01132 Elongation factor P (EF-P) OB domain 68 121 1.0E-23 T 28-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 CIG75_RS08285 f460a3f6a6345aaa161840b95294225c 185 ProSitePatterns PS01275 Elongation factor P signature. 150 169 - T 28-03-2018 IPR013852 Translation elongation factor P/YeiP, conserved site CIG75_RS08285 f460a3f6a6345aaa161840b95294225c 185 SMART SM01185 67 121 2.2E-27 T 28-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 CIG75_RS08285 f460a3f6a6345aaa161840b95294225c 185 SUPERFAMILY SSF50104 1 62 3.67E-22 T 28-03-2018 IPR008991 Translation protein SH3-like domain CIG75_RS08285 f460a3f6a6345aaa161840b95294225c 185 TIGRFAM TIGR00038 efp: translation elongation factor P 2 185 5.8E-82 T 28-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 CIG75_RS08285 f460a3f6a6345aaa161840b95294225c 185 Gene3D G3DSA:2.30.30.30 2 60 2.8E-26 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 CIG75_RS08285 f460a3f6a6345aaa161840b95294225c 185 SUPERFAMILY SSF50249 128 185 1.06E-17 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CIG75_RS08285 f460a3f6a6345aaa161840b95294225c 185 Hamap MF_00141 Elongation factor P [efp]. 1 185 51.82 T 28-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 CIG75_RS08285 f460a3f6a6345aaa161840b95294225c 185 Gene3D G3DSA:2.40.50.140 64 127 5.2E-27 T 28-03-2018 CIG75_RS08285 f460a3f6a6345aaa161840b95294225c 185 SUPERFAMILY SSF50249 65 126 1.71E-21 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CIG75_RS08285 f460a3f6a6345aaa161840b95294225c 185 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 60 2.3E-28 T 28-03-2018 IPR013185 Translation elongation factor, KOW-like CIG75_RS08285 f460a3f6a6345aaa161840b95294225c 185 SMART SM00841 129 184 3.0E-32 T 28-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 CIG75_RS08285 f460a3f6a6345aaa161840b95294225c 185 Pfam PF09285 Elongation factor P, C-terminal 129 184 2.1E-25 T 28-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 CIG75_RS08285 f460a3f6a6345aaa161840b95294225c 185 PIRSF PIRSF005901 1 185 1.7E-72 T 28-03-2018 IPR020599 Translation elongation factor P/YeiP CIG75_RS08285 f460a3f6a6345aaa161840b95294225c 185 Gene3D G3DSA:2.40.50.140 129 184 3.8E-26 T 28-03-2018 CIG75_RS06300 9697c2fe03caad1fe9123798e64091b5 47 SMART SM00257 3 47 1.5E-10 T 28-03-2018 IPR018392 LysM domain CIG75_RS06300 9697c2fe03caad1fe9123798e64091b5 47 Pfam PF01476 LysM domain 4 46 4.0E-14 T 28-03-2018 IPR018392 LysM domain CIG75_RS06300 9697c2fe03caad1fe9123798e64091b5 47 SUPERFAMILY SSF54106 2 47 4.32E-11 T 28-03-2018 IPR018392 LysM domain CIG75_RS06300 9697c2fe03caad1fe9123798e64091b5 47 Gene3D G3DSA:3.10.350.10 2 47 6.1E-17 T 28-03-2018 CIG75_RS16740 84e77ec79a4174c4cb9070a365884942 268 SUPERFAMILY SSF158430 8 127 1.57E-31 T 28-03-2018 CIG75_RS16740 84e77ec79a4174c4cb9070a365884942 268 Pfam PF11155 Domain of unknown function (DUF2935) 130 248 5.0E-27 T 28-03-2018 IPR021328 Protein of unknown function DUF2935 CIG75_RS16740 84e77ec79a4174c4cb9070a365884942 268 Pfam PF11155 Domain of unknown function (DUF2935) 8 118 6.3E-22 T 28-03-2018 IPR021328 Protein of unknown function DUF2935 CIG75_RS16740 84e77ec79a4174c4cb9070a365884942 268 SUPERFAMILY SSF158430 128 261 7.06E-36 T 28-03-2018 CIG75_RS07580 956e1a9066f40db723b0975a97a4f0f8 742 Gene3D G3DSA:3.10.20.30 525 613 0.002 T 28-03-2018 IPR012675 Beta-grasp domain CIG75_RS07580 956e1a9066f40db723b0975a97a4f0f8 742 Gene3D G3DSA:3.30.420.40 219 358 1.2E-19 T 28-03-2018 CIG75_RS07580 956e1a9066f40db723b0975a97a4f0f8 742 SUPERFAMILY SSF53067 18 212 5.61E-22 T 28-03-2018 CIG75_RS07580 956e1a9066f40db723b0975a97a4f0f8 742 Gene3D G3DSA:3.30.420.40 9 204 2.2E-26 T 28-03-2018 CIG75_RS07580 956e1a9066f40db723b0975a97a4f0f8 742 Gene3D G3DSA:3.10.20.30 393 488 0.002 T 28-03-2018 IPR012675 Beta-grasp domain CIG75_RS07580 956e1a9066f40db723b0975a97a4f0f8 742 Pfam PF14450 Cell division protein FtsA 224 381 7.4E-9 T 28-03-2018 CIG75_RS07580 956e1a9066f40db723b0975a97a4f0f8 742 SMART SM00842 18 213 2.8E-50 T 28-03-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 CIG75_RS07580 956e1a9066f40db723b0975a97a4f0f8 742 SUPERFAMILY SSF53067 220 391 1.1E-24 T 28-03-2018 CIG75_RS10220 1242e318c053420035969a4480ceba7d 438 SUPERFAMILY SSF53850 22 437 1.34E-71 T 28-03-2018 CIG75_RS10220 1242e318c053420035969a4480ceba7d 438 Pfam PF13416 Bacterial extracellular solute-binding protein 61 383 7.8E-35 T 28-03-2018 CIG75_RS10220 1242e318c053420035969a4480ceba7d 438 Gene3D G3DSA:3.40.190.10 21 209 1.5E-36 T 28-03-2018 CIG75_RS10220 1242e318c053420035969a4480ceba7d 438 Gene3D G3DSA:3.40.190.10 210 396 8.3E-8 T 28-03-2018 CIG75_RS08675 9e982734f4f9376e205d117034633aa6 466 SMART SM00530 44 98 3.1E-11 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS08675 9e982734f4f9376e205d117034633aa6 466 SUPERFAMILY SSF47413 37 101 3.1E-14 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CIG75_RS08675 9e982734f4f9376e205d117034633aa6 466 Gene3D G3DSA:1.10.260.40 32 89 1.2E-14 T 28-03-2018 CIG75_RS08675 9e982734f4f9376e205d117034633aa6 466 Gene3D G3DSA:1.25.40.10 207 268 3.5E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS08675 9e982734f4f9376e205d117034633aa6 466 Gene3D G3DSA:1.25.40.10 159 206 3.0E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS08675 9e982734f4f9376e205d117034633aa6 466 Gene3D G3DSA:1.25.40.10 119 158 5.9E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS08675 9e982734f4f9376e205d117034633aa6 466 SMART SM00028 307 340 170.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS08675 9e982734f4f9376e205d117034633aa6 466 SMART SM00028 145 178 150.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS08675 9e982734f4f9376e205d117034633aa6 466 SMART SM00028 267 300 0.1 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS08675 9e982734f4f9376e205d117034633aa6 466 SMART SM00028 227 260 0.28 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS08675 9e982734f4f9376e205d117034633aa6 466 SMART SM00028 425 458 18.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS08675 9e982734f4f9376e205d117034633aa6 466 SMART SM00028 385 418 3.7 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS08675 9e982734f4f9376e205d117034633aa6 466 SMART SM00028 185 218 160.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS08675 9e982734f4f9376e205d117034633aa6 466 SMART SM00028 347 380 13.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS08675 9e982734f4f9376e205d117034633aa6 466 SUPERFAMILY SSF48452 108 254 4.93E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS08675 9e982734f4f9376e205d117034633aa6 466 Pfam PF12844 Helix-turn-helix domain 42 100 1.9E-10 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS08675 9e982734f4f9376e205d117034633aa6 466 Pfam PF13432 Tetratricopeptide repeat 112 175 8.1E-5 T 28-03-2018 CIG75_RS08675 9e982734f4f9376e205d117034633aa6 466 Gene3D G3DSA:1.25.40.10 317 465 4.8E-21 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS08675 9e982734f4f9376e205d117034633aa6 466 Gene3D G3DSA:1.10.150.200 90 118 0.42 T 28-03-2018 CIG75_RS08675 9e982734f4f9376e205d117034633aa6 466 Gene3D G3DSA:1.10.150.200 269 316 2.3E-6 T 28-03-2018 CIG75_RS08675 9e982734f4f9376e205d117034633aa6 466 SUPERFAMILY SSF48452 227 377 1.04E-20 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS08675 9e982734f4f9376e205d117034633aa6 466 Pfam PF13424 Tetratricopeptide repeat 230 299 7.0E-9 T 28-03-2018 CIG75_RS08675 9e982734f4f9376e205d117034633aa6 466 SUPERFAMILY SSF48452 343 457 1.18E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS10440 7c124f0d3e9f577f97a40470928e1147 293 Pfam PF00795 Carbon-nitrogen hydrolase 6 274 2.8E-60 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CIG75_RS10440 7c124f0d3e9f577f97a40470928e1147 293 SUPERFAMILY SSF56317 1 292 1.7E-76 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CIG75_RS10440 7c124f0d3e9f577f97a40470928e1147 293 Gene3D G3DSA:3.60.110.10 1 293 6.5E-72 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CIG75_RS08215 1f677443e5eb853bedbfd7ef47851d80 640 Gene3D G3DSA:3.40.50.620 220 617 2.6E-81 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CIG75_RS08215 1f677443e5eb853bedbfd7ef47851d80 640 Gene3D G3DSA:3.60.20.10 1 219 2.2E-63 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CIG75_RS08215 1f677443e5eb853bedbfd7ef47851d80 640 SUPERFAMILY SSF56235 1 222 1.54E-68 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CIG75_RS08215 1f677443e5eb853bedbfd7ef47851d80 640 PIRSF PIRSF001589 1 626 4.1E-198 T 28-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 CIG75_RS08215 1f677443e5eb853bedbfd7ef47851d80 640 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 547 3.1E-162 T 28-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 CIG75_RS08215 1f677443e5eb853bedbfd7ef47851d80 640 Pfam PF13537 Glutamine amidotransferase domain 48 165 3.5E-46 T 28-03-2018 IPR017932 Glutamine amidotransferase type 2 domain CIG75_RS08215 1f677443e5eb853bedbfd7ef47851d80 640 SUPERFAMILY SSF52402 230 377 5.79E-83 T 28-03-2018 CIG75_RS08215 1f677443e5eb853bedbfd7ef47851d80 640 SUPERFAMILY SSF52402 467 605 5.79E-83 T 28-03-2018 CIG75_RS08215 1f677443e5eb853bedbfd7ef47851d80 640 Pfam PF00733 Asparagine synthase 239 610 4.9E-103 T 28-03-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 CIG75_RS12200 2e05903917e83e098b8d6c220b2fec1b 91 SUPERFAMILY SSF160544 7 86 5.49E-25 T 28-03-2018 IPR029025 Type III secretion system substrate exporter, C-terminal CIG75_RS12200 2e05903917e83e098b8d6c220b2fec1b 91 Pfam PF01312 FlhB HrpN YscU SpaS Family 7 82 3.0E-21 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CIG75_RS12200 2e05903917e83e098b8d6c220b2fec1b 91 Gene3D G3DSA:3.40.1690.10 7 86 3.2E-30 T 28-03-2018 IPR029025 Type III secretion system substrate exporter, C-terminal CIG75_RS10905 c4ba6966a2d5448c5c4fd4b33e092a8f 345 Gene3D G3DSA:3.40.1030.10 70 344 7.7E-112 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CIG75_RS10905 c4ba6966a2d5448c5c4fd4b33e092a8f 345 Gene3D G3DSA:1.20.970.10 1 69 7.4E-21 T 28-03-2018 CIG75_RS10905 c4ba6966a2d5448c5c4fd4b33e092a8f 345 Pfam PF02885 Glycosyl transferase family, helical bundle domain 5 63 2.0E-18 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CIG75_RS10905 c4ba6966a2d5448c5c4fd4b33e092a8f 345 SUPERFAMILY SSF47648 1 68 1.7E-19 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CIG75_RS10905 c4ba6966a2d5448c5c4fd4b33e092a8f 345 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 6 333 4.3E-133 T 28-03-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 CIG75_RS10905 c4ba6966a2d5448c5c4fd4b33e092a8f 345 SUPERFAMILY SSF52418 74 338 3.27E-101 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CIG75_RS10905 c4ba6966a2d5448c5c4fd4b33e092a8f 345 Pfam PF00591 Glycosyl transferase family, a/b domain 74 324 1.1E-101 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CIG75_RS10905 c4ba6966a2d5448c5c4fd4b33e092a8f 345 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 4 334 40.147 T 28-03-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 CIG75_RS01650 0710a9ee66ab527041c40ffd02aa8493 248 Gene3D G3DSA:3.40.50.410 129 242 1.6E-12 T 28-03-2018 IPR002035 von Willebrand factor, type A CIG75_RS01650 0710a9ee66ab527041c40ffd02aa8493 248 Gene3D G3DSA:3.40.50.410 3 94 2.3E-7 T 28-03-2018 IPR002035 von Willebrand factor, type A CIG75_RS01650 0710a9ee66ab527041c40ffd02aa8493 248 SUPERFAMILY SSF53300 7 68 4.9E-7 T 28-03-2018 IPR002035 von Willebrand factor, type A CIG75_RS01650 0710a9ee66ab527041c40ffd02aa8493 248 SUPERFAMILY SSF53300 133 229 1.78E-11 T 28-03-2018 IPR002035 von Willebrand factor, type A CIG75_RS01650 0710a9ee66ab527041c40ffd02aa8493 248 Pfam PF00092 von Willebrand factor type A domain 134 227 4.7E-7 T 28-03-2018 IPR002035 von Willebrand factor, type A CIG75_RS08095 6275042c44777bb10a52c5bb3793ab95 265 Pfam PF13614 AAA domain 4 163 6.4E-25 T 28-03-2018 IPR025669 AAA domain CIG75_RS08095 6275042c44777bb10a52c5bb3793ab95 265 Gene3D G3DSA:3.40.50.300 2 246 4.7E-54 T 28-03-2018 CIG75_RS08095 6275042c44777bb10a52c5bb3793ab95 265 PIRSF PIRSF003092 1 265 7.4E-89 T 28-03-2018 IPR025501 ATP binding protein MinD CIG75_RS08095 6275042c44777bb10a52c5bb3793ab95 265 TIGRFAM TIGR01968 minD_bact: septum site-determining protein MinD 3 260 4.9E-118 T 28-03-2018 IPR010223 ATP binding protein MinD, bacterial-type GO:0016887 CIG75_RS08095 6275042c44777bb10a52c5bb3793ab95 265 SUPERFAMILY SSF52540 5 244 2.1E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS06765 c813c5459329c8ebdf42f540277e1ca3 281 TIGRFAM TIGR01121 D_amino_aminoT: D-amino-acid transaminase 5 275 3.9E-89 T 28-03-2018 IPR005784 D-amino acid aminotransferase GO:0008483|GO:0030170|GO:0046416 KEGG: 00310+2.6.1.21|KEGG: 00330+2.6.1.21|KEGG: 00360+2.6.1.21|KEGG: 00472+2.6.1.21|KEGG: 00473+2.6.1.21 CIG75_RS06765 c813c5459329c8ebdf42f540277e1ca3 281 Pfam PF01063 Amino-transferase class IV 30 251 8.6E-53 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CIG75_RS06765 c813c5459329c8ebdf42f540277e1ca3 281 Gene3D G3DSA:3.30.470.10 2 130 5.3E-27 T 28-03-2018 CIG75_RS06765 c813c5459329c8ebdf42f540277e1ca3 281 ProSitePatterns PS00770 Aminotransferases class-IV signature. 177 206 - T 28-03-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 CIG75_RS06765 c813c5459329c8ebdf42f540277e1ca3 281 Gene3D G3DSA:3.20.10.10 131 278 2.0E-43 T 28-03-2018 CIG75_RS06765 c813c5459329c8ebdf42f540277e1ca3 281 SUPERFAMILY SSF56752 3 273 1.44E-77 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CIG75_RS19005 ebe4a18a863a2f4df07e3505c3a77cc2 348 Pfam PF03864 Phage major capsid protein E 15 346 7.0E-44 T 28-03-2018 IPR005564 Major capsid protein GpE GO:0019028 CIG75_RS19005 ebe4a18a863a2f4df07e3505c3a77cc2 348 Gene3D G3DSA:3.90.1690.10 12 348 3.3E-65 T 28-03-2018 CIG75_RS07360 1b1a86fdd5cc399f0f8c4db668235217 154 Gene3D G3DSA:3.30.530.20 1 148 1.0E-17 T 28-03-2018 IPR023393 START-like domain CIG75_RS07360 1b1a86fdd5cc399f0f8c4db668235217 154 SUPERFAMILY SSF55961 1 148 5.02E-18 T 28-03-2018 CIG75_RS07360 1b1a86fdd5cc399f0f8c4db668235217 154 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 1 147 7.0E-11 T 28-03-2018 IPR019587 Polyketide cyclase/dehydrase CIG75_RS19745 3fe5c5dea3e91119c34cc8f39b642ae1 395 Pfam PF03143 Elongation factor Tu C-terminal domain 299 393 2.2E-32 T 28-03-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal CIG75_RS19745 3fe5c5dea3e91119c34cc8f39b642ae1 395 Pfam PF03144 Elongation factor Tu domain 2 225 295 2.6E-17 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CIG75_RS19745 3fe5c5dea3e91119c34cc8f39b642ae1 395 SUPERFAMILY SSF50465 303 395 1.12E-34 T 28-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal CIG75_RS19745 3fe5c5dea3e91119c34cc8f39b642ae1 395 Gene3D G3DSA:3.40.50.300 75 191 6.7E-34 T 28-03-2018 CIG75_RS19745 3fe5c5dea3e91119c34cc8f39b642ae1 395 Gene3D G3DSA:3.40.50.300 2 74 6.9E-12 T 28-03-2018 CIG75_RS19745 3fe5c5dea3e91119c34cc8f39b642ae1 395 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 395 1.9E-230 T 28-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CIG75_RS19745 3fe5c5dea3e91119c34cc8f39b642ae1 395 Pfam PF00009 Elongation factor Tu GTP binding domain 10 201 1.3E-61 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CIG75_RS19745 3fe5c5dea3e91119c34cc8f39b642ae1 395 SUPERFAMILY SSF52540 6 219 8.33E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS19745 3fe5c5dea3e91119c34cc8f39b642ae1 395 PRINTS PR00315 GTP-binding elongation factor signature 94 105 4.1E-25 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CIG75_RS19745 3fe5c5dea3e91119c34cc8f39b642ae1 395 PRINTS PR00315 GTP-binding elongation factor signature 131 140 4.1E-25 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CIG75_RS19745 3fe5c5dea3e91119c34cc8f39b642ae1 395 PRINTS PR00315 GTP-binding elongation factor signature 58 66 4.1E-25 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CIG75_RS19745 3fe5c5dea3e91119c34cc8f39b642ae1 395 PRINTS PR00315 GTP-binding elongation factor signature 78 88 4.1E-25 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CIG75_RS19745 3fe5c5dea3e91119c34cc8f39b642ae1 395 PRINTS PR00315 GTP-binding elongation factor signature 14 27 4.1E-25 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CIG75_RS19745 3fe5c5dea3e91119c34cc8f39b642ae1 395 Gene3D G3DSA:2.40.30.10 192 299 9.5E-32 T 28-03-2018 CIG75_RS19745 3fe5c5dea3e91119c34cc8f39b642ae1 395 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 395 60.281 T 28-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CIG75_RS19745 3fe5c5dea3e91119c34cc8f39b642ae1 395 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 146 8.0E-16 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CIG75_RS19745 3fe5c5dea3e91119c34cc8f39b642ae1 395 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site CIG75_RS19745 3fe5c5dea3e91119c34cc8f39b642ae1 395 Gene3D G3DSA:2.40.30.10 301 394 2.5E-31 T 28-03-2018 CIG75_RS19745 3fe5c5dea3e91119c34cc8f39b642ae1 395 SUPERFAMILY SSF50447 205 300 9.23E-31 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CIG75_RS16230 f64f3aa1856c6a2311c1761e59dbb547 545 Gene3D G3DSA:3.40.190.10 174 308 2.3E-33 T 28-03-2018 CIG75_RS16230 f64f3aa1856c6a2311c1761e59dbb547 545 SUPERFAMILY SSF53850 36 534 4.52E-121 T 28-03-2018 CIG75_RS16230 f64f3aa1856c6a2311c1761e59dbb547 545 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 83 464 7.0E-76 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CIG75_RS16230 f64f3aa1856c6a2311c1761e59dbb547 545 Gene3D G3DSA:3.10.105.10 309 513 2.6E-44 T 28-03-2018 CIG75_RS16230 f64f3aa1856c6a2311c1761e59dbb547 545 PIRSF PIRSF002741 4 544 7.1E-105 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CIG75_RS16230 f64f3aa1856c6a2311c1761e59dbb547 545 Gene3D G3DSA:3.90.76.10 64 173 9.9E-33 T 28-03-2018 CIG75_RS18495 3f782631adda3a3d37934a8e536cd24a 397 SUPERFAMILY SSF53756 33 388 8.38E-77 T 28-03-2018 CIG75_RS18495 3f782631adda3a3d37934a8e536cd24a 397 Gene3D G3DSA:3.40.50.2000 34 201 9.1E-24 T 28-03-2018 CIG75_RS18495 3f782631adda3a3d37934a8e536cd24a 397 Pfam PF00534 Glycosyl transferases group 1 206 369 5.7E-36 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CIG75_RS18495 3f782631adda3a3d37934a8e536cd24a 397 Pfam PF13477 Glycosyl transferase 4-like 28 164 5.3E-20 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CIG75_RS18495 3f782631adda3a3d37934a8e536cd24a 397 Gene3D G3DSA:3.40.50.2000 202 371 3.5E-45 T 28-03-2018 CIG75_RS01010 03c42865b730df2acb069e8ddcf9f992 162 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 39 161 2.7E-17 T 28-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CIG75_RS01010 03c42865b730df2acb069e8ddcf9f992 162 SUPERFAMILY SSF55961 26 161 1.85E-37 T 28-03-2018 CIG75_RS01010 03c42865b730df2acb069e8ddcf9f992 162 Gene3D G3DSA:3.30.530.20 20 162 9.2E-30 T 28-03-2018 IPR023393 START-like domain CIG75_RS15725 c802da96e196d9e20794e37144c491ba 207 SUPERFAMILY SSF50242 29 131 2.98E-16 T 28-03-2018 IPR008993 Tissue inhibitor of metalloproteinases-like, OB-fold CIG75_RS15725 c802da96e196d9e20794e37144c491ba 207 Pfam PF00965 Tissue inhibitor of metalloproteinase 28 122 9.2E-5 T 28-03-2018 IPR001820 Protease inhibitor I35 (TIMP) GO:0008191 CIG75_RS15725 c802da96e196d9e20794e37144c491ba 207 Gene3D G3DSA:2.40.50.120 29 140 3.1E-14 T 28-03-2018 CIG75_RS18380 e1067748fa618677d68e85346b466abc 68 Pfam PF07870 Protein of unknown function (DUF1657) 7 55 5.3E-22 T 28-03-2018 IPR012452 Protein of unknown function DUF1657 CIG75_RS18380 e1067748fa618677d68e85346b466abc 68 Gene3D G3DSA:1.20.1260.10 3 67 6.4E-4 T 28-03-2018 IPR012347 Ferritin-related CIG75_RS08955 f0f4ce005023c3265b5def9261673096 409 Gene3D G3DSA:2.40.50.140 324 394 0.42 T 28-03-2018 CIG75_RS08955 f0f4ce005023c3265b5def9261673096 409 Gene3D G3DSA:2.40.50.140 240 307 0.089 T 28-03-2018 CIG75_RS08955 f0f4ce005023c3265b5def9261673096 409 Pfam PF00395 S-layer homology domain 176 220 5.2E-12 T 28-03-2018 IPR001119 S-layer homology domain CIG75_RS08955 f0f4ce005023c3265b5def9261673096 409 Pfam PF00395 S-layer homology domain 47 90 8.3E-8 T 28-03-2018 IPR001119 S-layer homology domain CIG75_RS19835 0e564e374bbd263a95b9f2793f93ddc8 462 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 16 313 8.0E-132 T 28-03-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 CIG75_RS19835 0e564e374bbd263a95b9f2793f93ddc8 462 SMART SM00840 349 413 1.3E-12 T 28-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 CIG75_RS19835 0e564e374bbd263a95b9f2793f93ddc8 462 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 62 71 9.6E-30 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CIG75_RS19835 0e564e374bbd263a95b9f2793f93ddc8 462 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 222 243 9.6E-30 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CIG75_RS19835 0e564e374bbd263a95b9f2793f93ddc8 462 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 26 37 9.6E-30 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CIG75_RS19835 0e564e374bbd263a95b9f2793f93ddc8 462 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 191 209 9.6E-30 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CIG75_RS19835 0e564e374bbd263a95b9f2793f93ddc8 462 SUPERFAMILY SSF52374 4 312 9.21E-100 T 28-03-2018 CIG75_RS19835 0e564e374bbd263a95b9f2793f93ddc8 462 Gene3D G3DSA:3.40.50.620 1 305 1.5E-91 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CIG75_RS19835 0e564e374bbd263a95b9f2793f93ddc8 462 Pfam PF09190 DALR domain 349 405 6.6E-13 T 28-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 CIG75_RS19835 0e564e374bbd263a95b9f2793f93ddc8 462 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 3 462 39.321 T 28-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 CIG75_RS19835 0e564e374bbd263a95b9f2793f93ddc8 462 SUPERFAMILY SSF47323 338 461 2.75E-34 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CIG75_RS19835 0e564e374bbd263a95b9f2793f93ddc8 462 Gene3D G3DSA:1.20.120.640 306 402 6.9E-19 T 28-03-2018 CIG75_RS19835 0e564e374bbd263a95b9f2793f93ddc8 462 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 4 461 1.5E-181 T 28-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 CIG75_RS13510 d3b1a5465a134b7c72bb023da1007c5e 492 SUPERFAMILY SSF63418 3 97 1.83E-25 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CIG75_RS13510 d3b1a5465a134b7c72bb023da1007c5e 492 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 20 488 1.1E-172 T 28-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 CIG75_RS13510 d3b1a5465a134b7c72bb023da1007c5e 492 Gene3D G3DSA:3.90.190.20 340 492 1.9E-52 T 28-03-2018 CIG75_RS13510 d3b1a5465a134b7c72bb023da1007c5e 492 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 105 129 - T 28-03-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 CIG75_RS13510 d3b1a5465a134b7c72bb023da1007c5e 492 Pfam PF02875 Mur ligase family, glutamate ligase domain 335 419 1.3E-23 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CIG75_RS13510 d3b1a5465a134b7c72bb023da1007c5e 492 Pfam PF08245 Mur ligase middle domain 107 314 1.6E-52 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CIG75_RS13510 d3b1a5465a134b7c72bb023da1007c5e 492 Gene3D G3DSA:3.40.1190.10 98 339 1.3E-64 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CIG75_RS13510 d3b1a5465a134b7c72bb023da1007c5e 492 SUPERFAMILY SSF53244 335 489 1.05E-50 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CIG75_RS13510 d3b1a5465a134b7c72bb023da1007c5e 492 Pfam PF01225 Mur ligase family, catalytic domain 22 95 1.8E-14 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CIG75_RS13510 d3b1a5465a134b7c72bb023da1007c5e 492 Gene3D G3DSA:3.40.1390.10 1 97 4.5E-29 T 28-03-2018 CIG75_RS13510 d3b1a5465a134b7c72bb023da1007c5e 492 SUPERFAMILY SSF53623 98 331 6.67E-71 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CIG75_RS13510 d3b1a5465a134b7c72bb023da1007c5e 492 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 1 488 36.659 T 28-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 CIG75_RS16625 aa2c961e146d642be0c5fba3ff139174 402 Gene3D G3DSA:1.20.1250.20 204 401 2.3E-14 T 28-03-2018 CIG75_RS16625 aa2c961e146d642be0c5fba3ff139174 402 Gene3D G3DSA:1.20.1250.20 4 185 1.7E-14 T 28-03-2018 CIG75_RS16625 aa2c961e146d642be0c5fba3ff139174 402 SUPERFAMILY SSF103473 6 392 3.92E-37 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS16625 aa2c961e146d642be0c5fba3ff139174 402 Pfam PF07690 Major Facilitator Superfamily 22 352 2.1E-24 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CIG75_RS05775 deb974e591060eb0c3f78ae0330e779f 88 Pfam PF11084 Protein of unknown function (DUF2621) 3 87 8.2E-14 T 28-03-2018 IPR020203 Uncharacterised protein family, YneK CIG75_RS05775 deb974e591060eb0c3f78ae0330e779f 88 ProDom PD086666 YNEK BH2332 3 88 8.0E-9 T 28-03-2018 IPR020203 Uncharacterised protein family, YneK CIG75_RS05775 deb974e591060eb0c3f78ae0330e779f 88 Pfam PF08369 Proto-chlorophyllide reductase 57 kD subunit 5 51 7.6E-8 T 28-03-2018 IPR013580 Proto-chlorophyllide/chlorophyllide reductase, C-terminal GO:0015979|GO:0015995|GO:0016491|GO:0055114 KEGG: 00860+1.3.7.7|MetaCyc: PWY-5531|MetaCyc: PWY-7159 CIG75_RS01260 dbe1abeb48b827630e59d53d7022b776 349 Pfam PF01636 Phosphotransferase enzyme family 43 260 2.2E-20 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CIG75_RS01260 dbe1abeb48b827630e59d53d7022b776 349 Gene3D G3DSA:3.90.1200.10 122 336 2.9E-14 T 28-03-2018 CIG75_RS01260 dbe1abeb48b827630e59d53d7022b776 349 Gene3D G3DSA:3.30.200.20 6 121 1.6E-8 T 28-03-2018 CIG75_RS01260 dbe1abeb48b827630e59d53d7022b776 349 SUPERFAMILY SSF56112 35 303 3.97E-29 T 28-03-2018 IPR011009 Protein kinase-like domain CIG75_RS16510 360e352c268a2324b1d32c81f72d14a1 566 SUPERFAMILY SSF58104 296 565 1.03E-72 T 28-03-2018 CIG75_RS16510 360e352c268a2324b1d32c81f72d14a1 566 SUPERFAMILY SSF58104 234 263 1.03E-72 T 28-03-2018 CIG75_RS16510 360e352c268a2324b1d32c81f72d14a1 566 SMART SM00304 208 261 4.0E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CIG75_RS16510 360e352c268a2324b1d32c81f72d14a1 566 Pfam PF12729 Four helix bundle sensory module for signal transduction 3 177 8.8E-21 T 28-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain CIG75_RS16510 360e352c268a2324b1d32c81f72d14a1 566 Gene3D G3DSA:1.10.287.950 324 566 2.0E-55 T 28-03-2018 CIG75_RS16510 360e352c268a2324b1d32c81f72d14a1 566 Gene3D G3DSA:1.10.287.1060 231 323 0.0027 T 28-03-2018 CIG75_RS16510 360e352c268a2324b1d32c81f72d14a1 566 SMART SM00283 290 565 2.5E-82 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CIG75_RS16510 360e352c268a2324b1d32c81f72d14a1 566 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 334 517 9.6E-43 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CIG75_RS16510 360e352c268a2324b1d32c81f72d14a1 566 Gene3D G3DSA:1.20.120.30 21 179 1.1E-14 T 28-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain CIG75_RS16510 360e352c268a2324b1d32c81f72d14a1 566 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 417 446 2.8E-22 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CIG75_RS16510 360e352c268a2324b1d32c81f72d14a1 566 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 1 20 2.8E-22 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CIG75_RS16510 360e352c268a2324b1d32c81f72d14a1 566 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 388 415 2.8E-22 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CIG75_RS16510 360e352c268a2324b1d32c81f72d14a1 566 Pfam PF00672 HAMP domain 208 257 1.3E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CIG75_RS16605 4ab8191285e18de913a8bc16b8dcd2aa 555 SUPERFAMILY SSF52540 8 227 7.79E-49 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS16605 4ab8191285e18de913a8bc16b8dcd2aa 555 Pfam PF00005 ABC transporter 27 165 1.8E-21 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS16605 4ab8191285e18de913a8bc16b8dcd2aa 555 Pfam PF00005 ABC transporter 319 462 5.6E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS16605 4ab8191285e18de913a8bc16b8dcd2aa 555 Gene3D G3DSA:3.40.50.300 5 235 1.9E-54 T 28-03-2018 CIG75_RS16605 4ab8191285e18de913a8bc16b8dcd2aa 555 Gene3D G3DSA:3.40.50.300 296 552 1.0E-61 T 28-03-2018 CIG75_RS16605 4ab8191285e18de913a8bc16b8dcd2aa 555 SUPERFAMILY SSF52540 298 527 2.11E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS16605 4ab8191285e18de913a8bc16b8dcd2aa 555 ProSitePatterns PS00211 ABC transporters family signature. 435 449 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS16605 4ab8191285e18de913a8bc16b8dcd2aa 555 SMART SM00382 36 213 1.1E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS16605 4ab8191285e18de913a8bc16b8dcd2aa 555 SMART SM00382 326 512 1.3E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS08875 e36a002833de507b59ff5bd3b8a5dd1a 144 SUPERFAMILY SSF51735 2 135 3.15E-38 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS08875 e36a002833de507b59ff5bd3b8a5dd1a 144 Gene3D G3DSA:3.40.50.720 14 136 4.6E-29 T 28-03-2018 CIG75_RS08875 e36a002833de507b59ff5bd3b8a5dd1a 144 Pfam PF13380 CoA binding domain 18 132 2.8E-37 T 28-03-2018 IPR003781 CoA-binding GO:0048037 CIG75_RS08875 e36a002833de507b59ff5bd3b8a5dd1a 144 SMART SM00881 14 106 7.6E-18 T 28-03-2018 IPR003781 CoA-binding GO:0048037 CIG75_RS00080 a2e2fab343bb3e43a03bc6b9cc1b9844 366 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 257 363 1.9E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS00080 a2e2fab343bb3e43a03bc6b9cc1b9844 366 SUPERFAMILY SSF47384 139 212 9.61E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CIG75_RS00080 a2e2fab343bb3e43a03bc6b9cc1b9844 366 Gene3D G3DSA:3.30.450.20 26 139 6.0E-7 T 28-03-2018 CIG75_RS00080 a2e2fab343bb3e43a03bc6b9cc1b9844 366 Gene3D G3DSA:3.30.565.10 213 364 3.3E-35 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS00080 a2e2fab343bb3e43a03bc6b9cc1b9844 366 PRINTS PR00344 Bacterial sensor protein C-terminal signature 349 362 1.0E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS00080 a2e2fab343bb3e43a03bc6b9cc1b9844 366 PRINTS PR00344 Bacterial sensor protein C-terminal signature 326 344 1.0E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS00080 a2e2fab343bb3e43a03bc6b9cc1b9844 366 PRINTS PR00344 Bacterial sensor protein C-terminal signature 297 311 1.0E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS00080 a2e2fab343bb3e43a03bc6b9cc1b9844 366 PRINTS PR00344 Bacterial sensor protein C-terminal signature 315 325 1.0E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS00080 a2e2fab343bb3e43a03bc6b9cc1b9844 366 Pfam PF00512 His Kinase A (phospho-acceptor) domain 149 212 1.2E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CIG75_RS00080 a2e2fab343bb3e43a03bc6b9cc1b9844 366 SMART SM00387 256 365 1.4E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS00080 a2e2fab343bb3e43a03bc6b9cc1b9844 366 SMART SM00388 147 215 1.1E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CIG75_RS00080 a2e2fab343bb3e43a03bc6b9cc1b9844 366 Gene3D G3DSA:1.10.287.130 140 211 1.3E-13 T 28-03-2018 CIG75_RS00080 a2e2fab343bb3e43a03bc6b9cc1b9844 366 SUPERFAMILY SSF55874 205 363 1.44E-35 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS04945 7dbd65aa5ff76e18c4525a4219918474 371 Pfam PF02073 Thermophilic metalloprotease (M29) 6 333 4.0E-63 T 28-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CIG75_RS04945 7dbd65aa5ff76e18c4525a4219918474 371 Gene3D G3DSA:3.40.1830.10 3 165 1.6E-44 T 28-03-2018 IPR035097 Peptidase M29, N-terminal CIG75_RS04945 7dbd65aa5ff76e18c4525a4219918474 371 SUPERFAMILY SSF144052 4 360 2.75E-108 T 28-03-2018 CIG75_RS06775 225e138d9f9c7124a77463108c18e9ba 599 TIGRFAM TIGR02290 M3_fam_3: oligoendopeptidase, pepF/M3 family 7 591 2.6E-197 T 28-03-2018 IPR011977 Peptidase M3B, oligoendopeptidase-related clade 3 CIG75_RS06775 225e138d9f9c7124a77463108c18e9ba 599 SUPERFAMILY SSF55486 55 582 1.34E-97 T 28-03-2018 CIG75_RS06775 225e138d9f9c7124a77463108c18e9ba 599 Gene3D G3DSA:1.10.1370.10 74 585 5.7E-13 T 28-03-2018 CIG75_RS06775 225e138d9f9c7124a77463108c18e9ba 599 Pfam PF08439 Oligopeptidase F 112 178 1.8E-7 T 28-03-2018 IPR013647 Oligopeptidase F, N-terminal domain CIG75_RS06775 225e138d9f9c7124a77463108c18e9ba 599 Pfam PF01432 Peptidase family M3 202 578 1.2E-19 T 28-03-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 CIG75_RS01950 7f7b44271a153e89ea6f9bfe2e0f5684 136 Gene3D G3DSA:1.20.5.440 89 131 1.9E-15 T 28-03-2018 CIG75_RS01950 7f7b44271a153e89ea6f9bfe2e0f5684 136 Gene3D G3DSA:2.60.15.10 1 88 7.5E-26 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CIG75_RS01950 7f7b44271a153e89ea6f9bfe2e0f5684 136 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 5 130 1.3E-33 T 28-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CIG75_RS01950 7f7b44271a153e89ea6f9bfe2e0f5684 136 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 9 82 8.0E-19 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CIG75_RS01950 7f7b44271a153e89ea6f9bfe2e0f5684 136 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 2 129 22.446 T 28-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CIG75_RS01950 7f7b44271a153e89ea6f9bfe2e0f5684 136 SUPERFAMILY SSF51344 3 84 2.62E-22 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CIG75_RS01950 7f7b44271a153e89ea6f9bfe2e0f5684 136 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 5 82 6.6E-27 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CIG75_RS01950 7f7b44271a153e89ea6f9bfe2e0f5684 136 SUPERFAMILY SSF46604 86 131 3.4E-9 T 28-03-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CIG75_RS01950 7f7b44271a153e89ea6f9bfe2e0f5684 136 Pfam PF00401 ATP synthase, Delta/Epsilon chain, long alpha-helix domain 86 130 3.3E-15 T 28-03-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CIG75_RS01830 1c538b299c4513d3e9d50b9272f2195c 340 Gene3D G3DSA:3.30.9.10 233 311 9.8E-4 T 28-03-2018 CIG75_RS01830 1c538b299c4513d3e9d50b9272f2195c 340 Gene3D G3DSA:3.90.870.10 1 210 1.4E-76 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CIG75_RS01830 1c538b299c4513d3e9d50b9272f2195c 340 SUPERFAMILY SSF55821 6 208 3.66E-65 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CIG75_RS01830 1c538b299c4513d3e9d50b9272f2195c 340 PIRSF PIRSF004930 1 340 9.4E-120 T 28-03-2018 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 CIG75_RS01830 1c538b299c4513d3e9d50b9272f2195c 340 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 9 203 1.0E-62 T 28-03-2018 IPR006070 YrdC-like domain GO:0003725 CIG75_RS01830 1c538b299c4513d3e9d50b9272f2195c 340 Pfam PF03481 Putative GTP-binding controlling metal-binding 196 334 5.9E-24 T 28-03-2018 IPR005145 Putative GTP-binding controlling metal-binding domain CIG75_RS01830 1c538b299c4513d3e9d50b9272f2195c 340 Pfam PF01300 Telomere recombination 18 194 5.0E-55 T 28-03-2018 IPR006070 YrdC-like domain GO:0003725 CIG75_RS03815 f9e43dec2b12e8e0bf75da4129c785ea 77 Gene3D G3DSA:3.30.950.10 26 77 1.7E-7 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CIG75_RS03815 f9e43dec2b12e8e0bf75da4129c785ea 77 SUPERFAMILY SSF53790 28 72 1.64E-6 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CIG75_RS17430 b7e08576a493f05e6900692997ad2002 259 Gene3D G3DSA:3.40.50.300 2 242 1.1E-54 T 28-03-2018 CIG75_RS17430 b7e08576a493f05e6900692997ad2002 259 SMART SM00382 28 216 8.9E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS17430 b7e08576a493f05e6900692997ad2002 259 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS17430 b7e08576a493f05e6900692997ad2002 259 Pfam PF00005 ABC transporter 19 165 5.2E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS17430 b7e08576a493f05e6900692997ad2002 259 SUPERFAMILY SSF52540 6 229 8.56E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS00475 65585fb65bc5a2c175f08f1106f6a0de 393 Gene3D G3DSA:3.30.460.10 24 143 0.0086 T 28-03-2018 CIG75_RS14765 0576bfcde1f977899eca3be45394d89f 147 Gene3D G3DSA:1.10.1510.10 1 90 4.1E-31 T 28-03-2018 CIG75_RS14765 0576bfcde1f977899eca3be45394d89f 147 Pfam PF09424 Yqey-like protein 5 146 1.7E-57 T 28-03-2018 IPR019004 Uncharacterised domain YOR215C, mitochondrial CIG75_RS14765 0576bfcde1f977899eca3be45394d89f 147 Gene3D G3DSA:1.10.10.410 91 147 1.0E-22 T 28-03-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal CIG75_RS14765 0576bfcde1f977899eca3be45394d89f 147 SUPERFAMILY SSF89095 1 146 6.8E-46 T 28-03-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 CIG75_RS11365 029609434983bf14acf0b66888eac628 110 Gene3D G3DSA:1.10.3420.10 1 109 4.1E-24 T 28-03-2018 CIG75_RS11365 029609434983bf14acf0b66888eac628 110 PIRSF PIRSF029904 1 110 4.4E-48 T 28-03-2018 IPR012359 NTP pyrophosphohydrolase MazG-related, YpjD CIG75_RS11365 029609434983bf14acf0b66888eac628 110 SUPERFAMILY SSF101386 2 104 3.11E-25 T 28-03-2018 CIG75_RS11365 029609434983bf14acf0b66888eac628 110 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 27 104 6.8E-15 T 28-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core CIG75_RS01090 20ce00919ed7f9face30ab63accc0be7 156 SUPERFAMILY SSF55729 5 141 5.93E-20 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CIG75_RS01090 20ce00919ed7f9face30ab63accc0be7 156 Pfam PF13673 Acetyltransferase (GNAT) domain 36 147 7.5E-11 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CIG75_RS01090 20ce00919ed7f9face30ab63accc0be7 156 Gene3D G3DSA:3.40.630.30 1 154 2.9E-18 T 28-03-2018 CIG75_RS09085 3a4685b86aafcaa0d3dec93f639eb99a 118 Pfam PF09585 Conserved hypothetical protein (Lin0512_fam) 4 116 1.6E-42 T 28-03-2018 IPR011719 Conserved hypothetical protein CHP02058 CIG75_RS09085 3a4685b86aafcaa0d3dec93f639eb99a 118 Gene3D G3DSA:3.30.1330.20 1 117 6.8E-46 T 28-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 CIG75_RS09085 3a4685b86aafcaa0d3dec93f639eb99a 118 TIGRFAM TIGR02058 lin0512_fam: conserved hypothetical protein 3 118 3.3E-52 T 28-03-2018 IPR011719 Conserved hypothetical protein CHP02058 CIG75_RS18755 fa6e64bb4f1cf999e7b54c784fd741f7 257 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 86 104 2.5E-33 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CIG75_RS18755 fa6e64bb4f1cf999e7b54c784fd741f7 257 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 104 130 2.5E-33 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CIG75_RS18755 fa6e64bb4f1cf999e7b54c784fd741f7 257 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 7 34 2.5E-33 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CIG75_RS18755 fa6e64bb4f1cf999e7b54c784fd741f7 257 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 155 183 2.5E-33 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CIG75_RS18755 fa6e64bb4f1cf999e7b54c784fd741f7 257 Pfam PF00902 Sec-independent protein translocase protein (TatC) 10 222 2.6E-53 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CIG75_RS18755 fa6e64bb4f1cf999e7b54c784fd741f7 257 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 8 227 1.2E-57 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CIG75_RS18755 fa6e64bb4f1cf999e7b54c784fd741f7 257 ProSitePatterns PS01218 TatC family signature. 155 174 - T 28-03-2018 IPR019820 Sec-independent periplasmic protein translocase, conserved site CIG75_RS18755 fa6e64bb4f1cf999e7b54c784fd741f7 257 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 5 242 16.796 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CIG75_RS17435 ccdfbcb26fa139b198bc1cec2d9d1afc 323 PRINTS PR00690 Adhesin family signature 82 99 9.1E-19 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CIG75_RS17435 ccdfbcb26fa139b198bc1cec2d9d1afc 323 PRINTS PR00690 Adhesin family signature 69 82 9.1E-19 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CIG75_RS17435 ccdfbcb26fa139b198bc1cec2d9d1afc 323 PRINTS PR00690 Adhesin family signature 38 56 9.1E-19 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CIG75_RS17435 ccdfbcb26fa139b198bc1cec2d9d1afc 323 PRINTS PR00690 Adhesin family signature 260 278 9.1E-19 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CIG75_RS17435 ccdfbcb26fa139b198bc1cec2d9d1afc 323 PRINTS PR00690 Adhesin family signature 207 228 9.1E-19 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CIG75_RS17435 ccdfbcb26fa139b198bc1cec2d9d1afc 323 Gene3D G3DSA:3.40.50.1980 27 201 5.4E-65 T 28-03-2018 CIG75_RS17435 ccdfbcb26fa139b198bc1cec2d9d1afc 323 PRINTS PR00691 Adhesin B signature 63 81 1.7E-17 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CIG75_RS17435 ccdfbcb26fa139b198bc1cec2d9d1afc 323 PRINTS PR00691 Adhesin B signature 82 101 1.7E-17 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CIG75_RS17435 ccdfbcb26fa139b198bc1cec2d9d1afc 323 PRINTS PR00691 Adhesin B signature 300 318 1.7E-17 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CIG75_RS17435 ccdfbcb26fa139b198bc1cec2d9d1afc 323 PRINTS PR00691 Adhesin B signature 38 59 1.7E-17 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CIG75_RS17435 ccdfbcb26fa139b198bc1cec2d9d1afc 323 PRINTS PR00691 Adhesin B signature 256 273 1.7E-17 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CIG75_RS17435 ccdfbcb26fa139b198bc1cec2d9d1afc 323 PRINTS PR00691 Adhesin B signature 207 224 1.7E-17 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CIG75_RS17435 ccdfbcb26fa139b198bc1cec2d9d1afc 323 Pfam PF01297 Zinc-uptake complex component A periplasmic 41 320 5.6E-85 T 28-03-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 CIG75_RS17435 ccdfbcb26fa139b198bc1cec2d9d1afc 323 Gene3D G3DSA:3.40.50.1980 202 322 5.1E-40 T 28-03-2018 CIG75_RS17435 ccdfbcb26fa139b198bc1cec2d9d1afc 323 SUPERFAMILY SSF53807 17 322 1.23E-93 T 28-03-2018 CIG75_RS06470 d65292214825b7ecb214ba1b5e704a79 188 PIRSF PIRSF000232 1 188 6.0E-42 T 28-03-2018 IPR026021 Putative NAD(P)H nitroreductase YdjA-like CIG75_RS06470 d65292214825b7ecb214ba1b5e704a79 188 Pfam PF00881 Nitroreductase family 9 167 3.4E-21 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CIG75_RS06470 d65292214825b7ecb214ba1b5e704a79 188 Gene3D G3DSA:3.40.109.10 2 188 6.5E-31 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CIG75_RS06470 d65292214825b7ecb214ba1b5e704a79 188 SUPERFAMILY SSF55469 3 185 1.96E-33 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CIG75_RS19220 eb495919bf84affe82535c6596fa621e 94 Gene3D G3DSA:3.40.1800.10 1 80 1.4E-5 T 28-03-2018 CIG75_RS13600 602b62caf4730892ff21fb26fa55c22d 266 SUPERFAMILY SSF53474 2 251 1.29E-47 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS13600 602b62caf4730892ff21fb26fa55c22d 266 Pfam PF00561 alpha/beta hydrolase fold 21 127 3.8E-17 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CIG75_RS13600 602b62caf4730892ff21fb26fa55c22d 266 Gene3D G3DSA:3.40.50.1820 17 253 2.1E-34 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS13600 602b62caf4730892ff21fb26fa55c22d 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 45 60 7.2E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CIG75_RS13600 602b62caf4730892ff21fb26fa55c22d 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 89 102 7.2E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CIG75_RS13600 602b62caf4730892ff21fb26fa55c22d 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 199 213 7.2E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CIG75_RS13600 602b62caf4730892ff21fb26fa55c22d 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 103 116 7.2E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CIG75_RS13870 b878fc9595afb38a2cfd5a843455bcab 78 Gene3D G3DSA:1.10.287.1040 7 74 3.0E-26 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CIG75_RS13870 b878fc9595afb38a2cfd5a843455bcab 78 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 9 50 1.0E-9 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CIG75_RS13870 b878fc9595afb38a2cfd5a843455bcab 78 PIRSF PIRSF006488 1 78 2.3E-23 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CIG75_RS13870 b878fc9595afb38a2cfd5a843455bcab 78 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 9 64 1.4E-24 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CIG75_RS13870 b878fc9595afb38a2cfd5a843455bcab 78 Pfam PF02609 Exonuclease VII small subunit 10 60 1.3E-22 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CIG75_RS13870 b878fc9595afb38a2cfd5a843455bcab 78 SUPERFAMILY SSF116842 3 68 1.44E-21 T 28-03-2018 CIG75_RS13870 b878fc9595afb38a2cfd5a843455bcab 78 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 9 69 15.806 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CIG75_RS01805 6b0d53e45d23b6c91bad2cdfd6632f8e 97 ProDom PD131510 MEMBRANE METAL-DEPENDENT ENZYME YQHQ SPANNING SIMILAR LIPOPROTEIN LIPOPROTEIN PROTEIN HYP001 27 79 4.0E-5 T 28-03-2018 IPR010787 Protein of unknown function DUF1385 CIG75_RS01805 6b0d53e45d23b6c91bad2cdfd6632f8e 97 Pfam PF07136 Protein of unknown function (DUF1385) 5 79 4.0E-9 T 28-03-2018 IPR010787 Protein of unknown function DUF1385 CIG75_RS00140 9a2b76dcf6b96e63f1f43211748932d0 196 SUPERFAMILY SSF52317 2 191 2.29E-50 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CIG75_RS00140 9a2b76dcf6b96e63f1f43211748932d0 196 ProSitePatterns PS01236 PdxT/SNO family family signature. 41 51 - T 28-03-2018 IPR021196 PdxT/SNO family, conserved site KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CIG75_RS00140 9a2b76dcf6b96e63f1f43211748932d0 196 Hamap MF_01615 Pyridoxal 5'-phosphate synthase subunit PdxT [pdxT]. 3 188 38.341 T 28-03-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CIG75_RS00140 9a2b76dcf6b96e63f1f43211748932d0 196 TIGRFAM TIGR03800 PLP_synth_Pdx2: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 2 186 2.4E-77 T 28-03-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CIG75_RS00140 9a2b76dcf6b96e63f1f43211748932d0 196 Pfam PF01174 SNO glutamine amidotransferase family 5 190 2.2E-63 T 28-03-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CIG75_RS00140 9a2b76dcf6b96e63f1f43211748932d0 196 PIRSF PIRSF005639 1 193 2.7E-73 T 28-03-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CIG75_RS00140 9a2b76dcf6b96e63f1f43211748932d0 196 Gene3D G3DSA:3.40.50.880 1 196 1.6E-47 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CIG75_RS09480 d5ece53e843969b6506ff683b11ed461 235 Gene3D G3DSA:3.40.1800.10 137 217 2.4E-9 T 28-03-2018 CIG75_RS09480 d5ece53e843969b6506ff683b11ed461 235 SMART SM00507 148 203 8.9E-4 T 28-03-2018 IPR003615 HNH nuclease CIG75_RS05145 a0ae6ff54b4315ea21184bb7f39008ab 298 Pfam PF07155 ECF-type riboflavin transporter, S component 113 268 4.3E-13 T 28-03-2018 IPR009825 ECF transporter, substrate-specific component-like GO:0016020 CIG75_RS19610 2c49b0cbdc6b184ce43d09e9c08e9768 37 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 36 - T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS19610 2c49b0cbdc6b184ce43d09e9c08e9768 37 SUPERFAMILY SSF57840 1 37 6.93E-17 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS19610 2c49b0cbdc6b184ce43d09e9c08e9768 37 Pfam PF00444 Ribosomal protein L36 1 37 2.9E-19 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS19610 2c49b0cbdc6b184ce43d09e9c08e9768 37 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 37 17.137 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS19610 2c49b0cbdc6b184ce43d09e9c08e9768 37 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 10 37 3.0E-8 T 28-03-2018 CIG75_RS19610 2c49b0cbdc6b184ce43d09e9c08e9768 37 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 37 1.2E-24 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS17290 7c151f28f4bbd02752278c2a01368707 753 SUPERFAMILY SSF69572 146 292 7.65E-7 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CIG75_RS17290 7c151f28f4bbd02752278c2a01368707 753 Pfam PF02624 YcaO cyclodehydratase, ATP-ad Mg2+-binding 384 716 3.2E-100 T 28-03-2018 IPR003776 YcaO-like domain CIG75_RS17290 7c151f28f4bbd02752278c2a01368707 753 Gene3D G3DSA:3.40.50.720 114 310 1.6E-15 T 28-03-2018 CIG75_RS17290 7c151f28f4bbd02752278c2a01368707 753 TIGRFAM TIGR03882 cyclo_dehyd_2: bacteriocin biosynthesis cyclodehydratase domain 174 340 2.4E-43 T 28-03-2018 IPR022291 Bacteriocin biosynthesis, cyclodehydratase domain CIG75_RS17290 7c151f28f4bbd02752278c2a01368707 753 TIGRFAM TIGR00702 TIGR00702: YcaO-type kinase domain 382 716 1.1E-37 T 28-03-2018 IPR003776 YcaO-like domain CIG75_RS17290 7c151f28f4bbd02752278c2a01368707 753 TIGRFAM TIGR03604 TOMM_cyclo_SagD: thiazole/oxazole-forming peptide maturase, SagD family component 385 751 1.5E-84 T 28-03-2018 IPR027624 Thiazole/oxazole-forming peptide maturase, SagD family component CIG75_RS02355 97fb92f5438a923df9a334a83a8af187 296 TIGRFAM TIGR02550 flagell_flgL: flagellar hook-associated protein 3 2 186 5.1E-52 T 28-03-2018 IPR013384 Flagellar hook-associated protein 3 GO:0009424|GO:0071973 CIG75_RS02355 97fb92f5438a923df9a334a83a8af187 296 Pfam PF00669 Bacterial flagellin N-terminal helical region 6 138 7.7E-24 T 28-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 CIG75_RS02355 97fb92f5438a923df9a334a83a8af187 296 Gene3D G3DSA:1.20.1330.10 38 270 1.3E-41 T 28-03-2018 CIG75_RS02355 97fb92f5438a923df9a334a83a8af187 296 Pfam PF00700 Bacterial flagellin C-terminal helical region 213 295 6.7E-8 T 28-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 CIG75_RS02355 97fb92f5438a923df9a334a83a8af187 296 SUPERFAMILY SSF64518 1 296 1.27E-65 T 28-03-2018 CIG75_RS02355 97fb92f5438a923df9a334a83a8af187 296 PRINTS PR00207 Flagellin signature 109 132 1.7E-5 T 28-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 CIG75_RS02355 97fb92f5438a923df9a334a83a8af187 296 PRINTS PR00207 Flagellin signature 74 93 1.7E-5 T 28-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 CIG75_RS02355 97fb92f5438a923df9a334a83a8af187 296 PRINTS PR00207 Flagellin signature 35 52 1.7E-5 T 28-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 CIG75_RS12330 1b943b249228709bd10dda8bff505f8a 311 SMART SM00382 101 281 5.6E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS12330 1b943b249228709bd10dda8bff505f8a 311 SUPERFAMILY SSF52540 57 305 4.13E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS12330 1b943b249228709bd10dda8bff505f8a 311 SMART SM00962 102 303 1.5E-121 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CIG75_RS12330 1b943b249228709bd10dda8bff505f8a 311 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 31 303 64.963 T 28-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 CIG75_RS12330 1b943b249228709bd10dda8bff505f8a 311 Gene3D G3DSA:1.20.120.140 1 99 5.2E-26 T 28-03-2018 CIG75_RS12330 1b943b249228709bd10dda8bff505f8a 311 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 276 289 - T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CIG75_RS12330 1b943b249228709bd10dda8bff505f8a 311 Pfam PF00448 SRP54-type protein, GTPase domain 103 302 6.7E-80 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CIG75_RS12330 1b943b249228709bd10dda8bff505f8a 311 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 31 302 8.7E-117 T 28-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 CIG75_RS12330 1b943b249228709bd10dda8bff505f8a 311 SMART SM00963 7 88 4.1E-23 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CIG75_RS12330 1b943b249228709bd10dda8bff505f8a 311 Gene3D G3DSA:3.40.50.300 100 304 5.6E-42 T 28-03-2018 CIG75_RS12330 1b943b249228709bd10dda8bff505f8a 311 SUPERFAMILY SSF47364 1 82 6.8E-23 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CIG75_RS12330 1b943b249228709bd10dda8bff505f8a 311 Pfam PF02881 SRP54-type protein, helical bundle domain 19 84 4.7E-16 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CIG75_RS15445 c40826ac4bd36f790ddcb0d6c0cbc732 219 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 48 217 1.4E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CIG75_RS15445 c40826ac4bd36f790ddcb0d6c0cbc732 219 SUPERFAMILY SSF161098 13 217 5.63E-43 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CIG75_RS15445 c40826ac4bd36f790ddcb0d6c0cbc732 219 Gene3D G3DSA:1.10.3720.10 3 219 1.0E-38 T 28-03-2018 CIG75_RS15445 c40826ac4bd36f790ddcb0d6c0cbc732 219 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 110 7.8E-27 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CIG75_RS08065 d62721628e13a260abee68180047c9d7 234 TIGRFAM TIGR00608 radc: DNA repair protein RadC 21 234 1.5E-76 T 28-03-2018 IPR001405 RadC protein CIG75_RS08065 d62721628e13a260abee68180047c9d7 234 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 183 188 - T 28-03-2018 IPR020891 Uncharacterised protein family UPF0758, conserved site CIG75_RS08065 d62721628e13a260abee68180047c9d7 234 Gene3D G3DSA:1.10.150.20 32 97 1.0E-5 T 28-03-2018 CIG75_RS08065 d62721628e13a260abee68180047c9d7 234 Pfam PF04002 RadC-like JAB domain 114 232 7.6E-47 T 28-03-2018 IPR025657 RadC-like JAB domain CIG75_RS08065 d62721628e13a260abee68180047c9d7 234 SUPERFAMILY SSF47781 25 100 1.78E-10 T 28-03-2018 IPR010994 RuvA domain 2-like CIG75_RS08065 d62721628e13a260abee68180047c9d7 234 Gene3D G3DSA:3.40.140.10 109 234 2.7E-50 T 28-03-2018 CIG75_RS17875 145d6c4115266d747be15b2bb673fc3d 157 Gene3D G3DSA:1.10.10.10 25 112 1.5E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS17875 145d6c4115266d747be15b2bb673fc3d 157 SUPERFAMILY SSF46785 24 154 6.02E-32 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS17875 145d6c4115266d747be15b2bb673fc3d 157 Pfam PF01475 Ferric uptake regulator family 31 149 1.5E-27 T 28-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CIG75_RS17655 1937b81e1bce57abf5d38a4795fb3ee2 332 Gene3D G3DSA:3.10.50.40 119 289 1.3E-8 T 28-03-2018 CIG75_RS17655 1937b81e1bce57abf5d38a4795fb3ee2 332 Pfam PF13145 PPIC-type PPIASE domain 151 276 3.5E-13 T 28-03-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 CIG75_RS17655 1937b81e1bce57abf5d38a4795fb3ee2 332 SUPERFAMILY SSF109998 39 187 1.14E-12 T 28-03-2018 IPR027304 Trigger factor/SurA domain CIG75_RS13320 e83f626cd7ac1eeb6e41a8dbfcb222a6 261 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CIG75_RS13320 e83f626cd7ac1eeb6e41a8dbfcb222a6 261 Gene3D G3DSA:3.40.50.720 1 260 3.4E-70 T 28-03-2018 CIG75_RS13320 e83f626cd7ac1eeb6e41a8dbfcb222a6 261 Pfam PF00106 short chain dehydrogenase 9 200 4.3E-60 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS13320 e83f626cd7ac1eeb6e41a8dbfcb222a6 261 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 237 256 1.1E-59 T 28-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 CIG75_RS13320 e83f626cd7ac1eeb6e41a8dbfcb222a6 261 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 15 32 1.1E-59 T 28-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 CIG75_RS13320 e83f626cd7ac1eeb6e41a8dbfcb222a6 261 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 172 195 1.1E-59 T 28-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 CIG75_RS13320 e83f626cd7ac1eeb6e41a8dbfcb222a6 261 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 107 127 1.1E-59 T 28-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 CIG75_RS13320 e83f626cd7ac1eeb6e41a8dbfcb222a6 261 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 87 104 1.1E-59 T 28-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 CIG75_RS13320 e83f626cd7ac1eeb6e41a8dbfcb222a6 261 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 211 230 1.1E-59 T 28-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 CIG75_RS13320 e83f626cd7ac1eeb6e41a8dbfcb222a6 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 2.5E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS13320 e83f626cd7ac1eeb6e41a8dbfcb222a6 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 2.5E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS13320 e83f626cd7ac1eeb6e41a8dbfcb222a6 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 2.5E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS13320 e83f626cd7ac1eeb6e41a8dbfcb222a6 261 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 179 0.0019 T 28-03-2018 CIG75_RS13320 e83f626cd7ac1eeb6e41a8dbfcb222a6 261 SUPERFAMILY SSF51735 7 259 4.27E-74 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS13320 e83f626cd7ac1eeb6e41a8dbfcb222a6 261 TIGRFAM TIGR04316 dhbA_paeA: 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase 11 260 9.1E-117 T 28-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 CIG75_RS07110 cc2ffd9e3ecee2610648e2c2f840d751 194 Pfam PF12836 Helix-hairpin-helix motif 130 191 4.9E-20 T 28-03-2018 CIG75_RS07110 cc2ffd9e3ecee2610648e2c2f840d751 194 SUPERFAMILY SSF47781 120 193 1.07E-26 T 28-03-2018 IPR010994 RuvA domain 2-like CIG75_RS07110 cc2ffd9e3ecee2610648e2c2f840d751 194 SMART SM00278 171 190 100.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CIG75_RS07110 cc2ffd9e3ecee2610648e2c2f840d751 194 SMART SM00278 141 160 0.052 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CIG75_RS07110 cc2ffd9e3ecee2610648e2c2f840d751 194 Pfam PF10531 SLBB domain 55 109 1.0E-14 T 28-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CIG75_RS07110 cc2ffd9e3ecee2610648e2c2f840d751 194 Gene3D G3DSA:1.10.150.20 48 150 1.3E-10 T 28-03-2018 CIG75_RS07110 cc2ffd9e3ecee2610648e2c2f840d751 194 TIGRFAM TIGR00426 TIGR00426: competence protein ComEA helix-hairpin-helix repeat region 131 191 2.3E-16 T 28-03-2018 IPR004509 Competence protein ComEA, helix-hairpin-helix domain CIG75_RS07110 cc2ffd9e3ecee2610648e2c2f840d751 194 Gene3D G3DSA:1.10.150.310 151 194 4.4E-13 T 28-03-2018 CIG75_RS06590 ae7f426206fd36f96d923f039d7acec0 255 SUPERFAMILY SSF54197 15 132 2.32E-21 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 CIG75_RS06590 ae7f426206fd36f96d923f039d7acec0 255 Gene3D G3DSA:3.30.428.10 25 153 4.3E-14 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 CIG75_RS06590 ae7f426206fd36f96d923f039d7acec0 255 Pfam PF16285 Domain of unknown function (DUF4931) 11 255 4.6E-113 T 28-03-2018 CIG75_RS06590 ae7f426206fd36f96d923f039d7acec0 255 PIRSF PIRSF031505 1 255 5.9E-96 T 28-03-2018 IPR012361 Galactose-1-phosphate uridylyltransferase, short form, putative CIG75_RS10035 8b79beadaaa8ca595ee157d5e7125535 456 Pfam PF13167 GTP-binding GTPase N-terminal 33 118 4.9E-32 T 28-03-2018 IPR025121 GTPase HflX, N-terminal CIG75_RS10035 8b79beadaaa8ca595ee157d5e7125535 456 Pfam PF01926 50S ribosome-binding GTPase 206 331 2.1E-17 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CIG75_RS10035 8b79beadaaa8ca595ee157d5e7125535 456 Gene3D G3DSA:3.40.50.300 7 272 3.3E-14 T 28-03-2018 CIG75_RS10035 8b79beadaaa8ca595ee157d5e7125535 456 Pfam PF16360 GTP-binding GTPase Middle Region 120 198 1.4E-31 T 28-03-2018 IPR032305 GTP-binding protein, middle domain CIG75_RS10035 8b79beadaaa8ca595ee157d5e7125535 456 Gene3D G3DSA:1.20.120.430 275 442 1.0E-13 T 28-03-2018 CIG75_RS10035 8b79beadaaa8ca595ee157d5e7125535 456 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 206 226 1.7E-5 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CIG75_RS10035 8b79beadaaa8ca595ee157d5e7125535 456 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 280 298 1.7E-5 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CIG75_RS10035 8b79beadaaa8ca595ee157d5e7125535 456 Hamap MF_00900 GTPase HflX [hflX]. 33 400 45.035 T 28-03-2018 IPR016496 GTPase HflX GO:0005525 CIG75_RS10035 8b79beadaaa8ca595ee157d5e7125535 456 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 13 369 3.7E-135 T 28-03-2018 IPR016496 GTPase HflX GO:0005525 CIG75_RS10035 8b79beadaaa8ca595ee157d5e7125535 456 SUPERFAMILY SSF52540 195 374 3.1E-34 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS10035 8b79beadaaa8ca595ee157d5e7125535 456 PIRSF PIRSF006809 4 432 1.1E-144 T 28-03-2018 IPR016496 GTPase HflX GO:0005525 CIG75_RS12550 1304a1e50fcdfb9a017db539942027fb 901 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 204 339 2.4E-31 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CIG75_RS12550 1304a1e50fcdfb9a017db539942027fb 901 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 77 201 7.4E-19 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CIG75_RS12550 1304a1e50fcdfb9a017db539942027fb 901 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 603 719 1.2E-34 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CIG75_RS12550 1304a1e50fcdfb9a017db539942027fb 901 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 320 326 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CIG75_RS12550 1304a1e50fcdfb9a017db539942027fb 901 Pfam PF00702 haloacid dehalogenase-like hydrolase 524 643 7.0E-22 T 28-03-2018 CIG75_RS12550 1304a1e50fcdfb9a017db539942027fb 901 SUPERFAMILY SSF56784 483 734 1.15E-65 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS12550 1304a1e50fcdfb9a017db539942027fb 901 SUPERFAMILY SSF56784 316 336 1.15E-65 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS12550 1304a1e50fcdfb9a017db539942027fb 901 Gene3D G3DSA:3.40.1110.10 281 527 2.7E-55 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CIG75_RS12550 1304a1e50fcdfb9a017db539942027fb 901 Pfam PF00689 Cation transporting ATPase, C-terminus 713 884 3.4E-50 T 28-03-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 CIG75_RS12550 1304a1e50fcdfb9a017db539942027fb 901 Pfam PF00122 E1-E2 ATPase 105 297 5.6E-59 T 28-03-2018 CIG75_RS12550 1304a1e50fcdfb9a017db539942027fb 901 TIGRFAM TIGR01522 ATPase-IIA2_Ca: calcium-transporting P-type ATPase, PMR1-type 13 874 5.6E-243 T 28-03-2018 IPR006413 P-type ATPase, subfamily IIA, PMR1-type GO:0005388|GO:0006816|GO:0016021 Reactome: R-HSA-936837 CIG75_RS12550 1304a1e50fcdfb9a017db539942027fb 901 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 527 538 1.2E-40 T 28-03-2018 CIG75_RS12550 1304a1e50fcdfb9a017db539942027fb 901 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 318 332 1.2E-40 T 28-03-2018 CIG75_RS12550 1304a1e50fcdfb9a017db539942027fb 901 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 155 169 1.2E-40 T 28-03-2018 CIG75_RS12550 1304a1e50fcdfb9a017db539942027fb 901 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 629 648 1.2E-40 T 28-03-2018 CIG75_RS12550 1304a1e50fcdfb9a017db539942027fb 901 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 549 559 1.2E-40 T 28-03-2018 CIG75_RS12550 1304a1e50fcdfb9a017db539942027fb 901 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 653 665 1.2E-40 T 28-03-2018 CIG75_RS12550 1304a1e50fcdfb9a017db539942027fb 901 TIGRFAM TIGR01116 ATPase-IIA1_Ca: calcium-translocating P-type ATPase, SERCA-type 47 876 6.1E-223 T 28-03-2018 IPR005782 P-type ATPase, subfamily IIA, SERCA-type GO:0005388|GO:0006816|GO:0016021 Reactome: R-HSA-1912420|Reactome: R-HSA-418359|Reactome: R-HSA-5578775|Reactome: R-HSA-936837 CIG75_RS12550 1304a1e50fcdfb9a017db539942027fb 901 Pfam PF00690 Cation transporter/ATPase, N-terminus 2 65 1.9E-17 T 28-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 CIG75_RS12550 1304a1e50fcdfb9a017db539942027fb 901 SUPERFAMILY SSF81665 219 312 1.57E-130 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CIG75_RS12550 1304a1e50fcdfb9a017db539942027fb 901 SUPERFAMILY SSF81665 679 884 1.57E-130 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CIG75_RS12550 1304a1e50fcdfb9a017db539942027fb 901 SUPERFAMILY SSF81665 2 108 1.57E-130 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CIG75_RS12550 1304a1e50fcdfb9a017db539942027fb 901 Gene3D G3DSA:1.20.1110.10 650 892 5.5E-75 T 28-03-2018 CIG75_RS12550 1304a1e50fcdfb9a017db539942027fb 901 PRINTS PR00121 Sodium/potassium-transporting ATPase signature 71 91 2.1E-16 T 28-03-2018 CIG75_RS12550 1304a1e50fcdfb9a017db539942027fb 901 PRINTS PR00121 Sodium/potassium-transporting ATPase signature 453 471 2.1E-16 T 28-03-2018 CIG75_RS12550 1304a1e50fcdfb9a017db539942027fb 901 PRINTS PR00121 Sodium/potassium-transporting ATPase signature 311 332 2.1E-16 T 28-03-2018 CIG75_RS12550 1304a1e50fcdfb9a017db539942027fb 901 SUPERFAMILY SSF81660 325 531 3.27E-65 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CIG75_RS12550 1304a1e50fcdfb9a017db539942027fb 901 Pfam PF13246 Cation transport ATPase (P-type) 378 468 7.5E-21 T 28-03-2018 CIG75_RS12550 1304a1e50fcdfb9a017db539942027fb 901 Gene3D G3DSA:2.70.150.10 6 219 1.4E-48 T 28-03-2018 CIG75_RS12550 1304a1e50fcdfb9a017db539942027fb 901 SUPERFAMILY SSF81653 108 218 5.75E-32 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CIG75_RS12550 1304a1e50fcdfb9a017db539942027fb 901 SMART SM00831 1 70 4.0E-20 T 28-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 CIG75_RS12550 1304a1e50fcdfb9a017db539942027fb 901 Gene3D G3DSA:3.40.50.1000 528 649 2.9E-20 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS09605 3a4c92a8ebfb7ee8f592372845837d30 529 Pfam PF00199 Catalase 16 406 1.0E-170 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CIG75_RS09605 3a4c92a8ebfb7ee8f592372845837d30 529 Gene3D G3DSA:2.40.180.10 1 372 3.6E-153 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CIG75_RS09605 3a4c92a8ebfb7ee8f592372845837d30 529 SMART SM01060 16 410 7.3E-248 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CIG75_RS09605 3a4c92a8ebfb7ee8f592372845837d30 529 PRINTS PR00067 Catalase signature 29 52 1.1E-66 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CIG75_RS09605 3a4c92a8ebfb7ee8f592372845837d30 529 PRINTS PR00067 Catalase signature 303 330 1.1E-66 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CIG75_RS09605 3a4c92a8ebfb7ee8f592372845837d30 529 PRINTS PR00067 Catalase signature 137 155 1.1E-66 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CIG75_RS09605 3a4c92a8ebfb7ee8f592372845837d30 529 PRINTS PR00067 Catalase signature 335 361 1.1E-66 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CIG75_RS09605 3a4c92a8ebfb7ee8f592372845837d30 529 PRINTS PR00067 Catalase signature 97 115 1.1E-66 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CIG75_RS09605 3a4c92a8ebfb7ee8f592372845837d30 529 PRINTS PR00067 Catalase signature 118 135 1.1E-66 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CIG75_RS09605 3a4c92a8ebfb7ee8f592372845837d30 529 PIRSF PIRSF038928 4 500 4.2E-176 T 28-03-2018 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CIG75_RS09605 3a4c92a8ebfb7ee8f592372845837d30 529 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 348 356 - T 28-03-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CIG75_RS09605 3a4c92a8ebfb7ee8f592372845837d30 529 ProSitePatterns PS00438 Catalase proximal active site signature. 52 68 - T 28-03-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CIG75_RS09605 3a4c92a8ebfb7ee8f592372845837d30 529 Pfam PF06628 Catalase-related immune-responsive 432 494 7.9E-18 T 28-03-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CIG75_RS09605 3a4c92a8ebfb7ee8f592372845837d30 529 SUPERFAMILY SSF56634 9 495 2.22E-191 T 28-03-2018 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CIG75_RS14735 4559650dbb8fdb9b0c55d8278177d707 320 SUPERFAMILY SSF52540 112 298 9.56E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS14735 4559650dbb8fdb9b0c55d8278177d707 320 Gene3D G3DSA:3.40.50.300 111 316 2.9E-31 T 28-03-2018 CIG75_RS14735 4559650dbb8fdb9b0c55d8278177d707 320 Pfam PF02562 PhoH-like protein 113 316 1.8E-96 T 28-03-2018 IPR003714 PhoH-like protein GO:0005524 CIG75_RS19495 8b497bc2891cd89476a8d3cb968d8f72 331 Gene3D G3DSA:1.20.58.410 1 84 1.5E-19 T 28-03-2018 CIG75_RS19495 8b497bc2891cd89476a8d3cb968d8f72 331 Hamap MF_00094 Peptide chain release factor 2 [prfB]. 1 327 37.58 T 28-03-2018 IPR020853 Peptide chain release factor 2, bacterial GO:0005737|GO:0006415|GO:0016149 CIG75_RS19495 8b497bc2891cd89476a8d3cb968d8f72 331 Pfam PF00472 RF-1 domain 190 299 1.0E-41 T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CIG75_RS19495 8b497bc2891cd89476a8d3cb968d8f72 331 Pfam PF03462 PCRF domain 2 181 3.4E-57 T 28-03-2018 IPR005139 Peptide chain release factor GO:0006415 CIG75_RS19495 8b497bc2891cd89476a8d3cb968d8f72 331 SUPERFAMILY SSF75620 2 329 4.58E-133 T 28-03-2018 CIG75_RS19495 8b497bc2891cd89476a8d3cb968d8f72 331 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 206 222 - T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CIG75_RS19495 8b497bc2891cd89476a8d3cb968d8f72 331 SMART SM00937 46 156 5.0E-54 T 28-03-2018 IPR005139 Peptide chain release factor GO:0006415 CIG75_RS19495 8b497bc2891cd89476a8d3cb968d8f72 331 Gene3D G3DSA:3.30.160.20 187 269 4.2E-34 T 28-03-2018 CIG75_RS19495 8b497bc2891cd89476a8d3cb968d8f72 331 TIGRFAM TIGR00020 prfB: peptide chain release factor 2 2 326 6.3E-159 T 28-03-2018 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 CIG75_RS03395 9a35f33c09e44e2c2e1bde48701b9f79 547 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 14 465 3.8E-92 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CIG75_RS03395 9a35f33c09e44e2c2e1bde48701b9f79 547 Gene3D G3DSA:1.20.210.10 2 542 5.4E-94 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CIG75_RS03395 9a35f33c09e44e2c2e1bde48701b9f79 547 SUPERFAMILY SSF81442 14 539 8.9E-116 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CIG75_RS03395 9a35f33c09e44e2c2e1bde48701b9f79 547 PRINTS PR01165 Cytochrome c oxidase subunit I signature 49 72 8.7E-15 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CIG75_RS03395 9a35f33c09e44e2c2e1bde48701b9f79 547 PRINTS PR01165 Cytochrome c oxidase subunit I signature 417 438 8.7E-15 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CIG75_RS03395 9a35f33c09e44e2c2e1bde48701b9f79 547 PRINTS PR01165 Cytochrome c oxidase subunit I signature 286 307 8.7E-15 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CIG75_RS03395 9a35f33c09e44e2c2e1bde48701b9f79 547 PRINTS PR01165 Cytochrome c oxidase subunit I signature 215 236 8.7E-15 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CIG75_RS03395 9a35f33c09e44e2c2e1bde48701b9f79 547 PRINTS PR01165 Cytochrome c oxidase subunit I signature 117 129 8.7E-15 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CIG75_RS03395 9a35f33c09e44e2c2e1bde48701b9f79 547 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 217 271 - T 28-03-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CIG75_RS15945 198f5e86c8579be3a9fe21ce1a9e520d 228 SMART SM00382 34 220 3.9E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS15945 198f5e86c8579be3a9fe21ce1a9e520d 228 Gene3D G3DSA:3.40.50.300 1 224 1.9E-64 T 28-03-2018 CIG75_RS15945 198f5e86c8579be3a9fe21ce1a9e520d 228 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS15945 198f5e86c8579be3a9fe21ce1a9e520d 228 SUPERFAMILY SSF52540 5 221 5.99E-67 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS15945 198f5e86c8579be3a9fe21ce1a9e520d 228 Pfam PF00005 ABC transporter 25 171 5.2E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS18615 6086528505631574958fc1b9222b7843 273 SUPERFAMILY SSF102114 28 187 1.7E-9 T 28-03-2018 CIG75_RS18615 6086528505631574958fc1b9222b7843 273 SMART SM00729 24 244 0.0076 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CIG75_RS18615 6086528505631574958fc1b9222b7843 273 Pfam PF04055 Radical SAM superfamily 29 188 3.3E-13 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CIG75_RS18615 6086528505631574958fc1b9222b7843 273 Gene3D G3DSA:3.20.20.70 8 216 5.1E-19 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CIG75_RS04125 2da93a092856d509226f5d8327ed6823 491 SUPERFAMILY SSF47413 59 118 1.35E-13 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CIG75_RS04125 2da93a092856d509226f5d8327ed6823 491 SMART SM00530 63 117 2.1E-11 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS04125 2da93a092856d509226f5d8327ed6823 491 Gene3D G3DSA:1.25.40.10 180 237 1.7E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS04125 2da93a092856d509226f5d8327ed6823 491 Gene3D G3DSA:1.25.40.10 330 489 1.6E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS04125 2da93a092856d509226f5d8327ed6823 491 SUPERFAMILY SSF48452 426 475 2.96E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS04125 2da93a092856d509226f5d8327ed6823 491 SUPERFAMILY SSF48452 247 383 2.96E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS04125 2da93a092856d509226f5d8327ed6823 491 Gene3D G3DSA:1.25.40.10 106 179 1.3E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS04125 2da93a092856d509226f5d8327ed6823 491 Gene3D G3DSA:1.10.260.40 52 105 1.0E-13 T 28-03-2018 CIG75_RS04125 2da93a092856d509226f5d8327ed6823 491 SUPERFAMILY SSF48452 164 285 1.19E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS04125 2da93a092856d509226f5d8327ed6823 491 Gene3D G3DSA:1.10.150.200 241 309 0.0058 T 28-03-2018 CIG75_RS04125 2da93a092856d509226f5d8327ed6823 491 Pfam PF01381 Helix-turn-helix 64 117 6.5E-10 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS14840 1b8da807aab4ea3571e18ded3e8b0b8b 378 Gene3D G3DSA:3.20.20.70 2 311 2.4E-56 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CIG75_RS14840 1b8da807aab4ea3571e18ded3e8b0b8b 378 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 5 368 3.5E-111 T 28-03-2018 IPR004559 Coproporphyrinogen III oxidase, oxygen-independent related GO:0004109|GO:0005737|GO:0006779|GO:0055114 CIG75_RS14840 1b8da807aab4ea3571e18ded3e8b0b8b 378 SUPERFAMILY SSF102114 5 377 2.88E-124 T 28-03-2018 CIG75_RS14840 1b8da807aab4ea3571e18ded3e8b0b8b 378 Pfam PF04055 Radical SAM superfamily 8 178 7.0E-25 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CIG75_RS14840 1b8da807aab4ea3571e18ded3e8b0b8b 378 Pfam PF06969 HemN C-terminal domain 309 367 1.5E-13 T 28-03-2018 IPR010723 HemN, C-terminal CIG75_RS14840 1b8da807aab4ea3571e18ded3e8b0b8b 378 SMART SM00729 3 223 8.0E-63 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CIG75_RS11720 77ff0029beda5c3ae9fd00d9c6f06dad 405 Pfam PF00696 Amino acid kinase family 3 233 1.2E-47 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CIG75_RS11720 77ff0029beda5c3ae9fd00d9c6f06dad 405 Gene3D G3DSA:3.40.1160.10 1 238 2.2E-67 T 28-03-2018 CIG75_RS11720 77ff0029beda5c3ae9fd00d9c6f06dad 405 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 63 401 1.8E-99 T 28-03-2018 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CIG75_RS11720 77ff0029beda5c3ae9fd00d9c6f06dad 405 Gene3D G3DSA:3.30.2130.10 334 404 1.1E-11 T 28-03-2018 CIG75_RS11720 77ff0029beda5c3ae9fd00d9c6f06dad 405 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 28-03-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CIG75_RS11720 77ff0029beda5c3ae9fd00d9c6f06dad 405 PIRSF PIRSF000726 1 65 4.6E-10 T 28-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CIG75_RS11720 77ff0029beda5c3ae9fd00d9c6f06dad 405 PIRSF PIRSF000726 60 404 2.0E-96 T 28-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CIG75_RS11720 77ff0029beda5c3ae9fd00d9c6f06dad 405 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 1 402 1.5E-133 T 28-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CIG75_RS11720 77ff0029beda5c3ae9fd00d9c6f06dad 405 SUPERFAMILY SSF55021 336 403 9.16E-14 T 28-03-2018 CIG75_RS11720 77ff0029beda5c3ae9fd00d9c6f06dad 405 Pfam PF13840 ACT domain 335 398 1.6E-18 T 28-03-2018 IPR027795 GATS-like ACT domain CIG75_RS11720 77ff0029beda5c3ae9fd00d9c6f06dad 405 SUPERFAMILY SSF53633 4 247 1.57E-69 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CIG75_RS11720 77ff0029beda5c3ae9fd00d9c6f06dad 405 Gene3D G3DSA:3.30.70.260 239 333 9.4E-20 T 28-03-2018 CIG75_RS11720 77ff0029beda5c3ae9fd00d9c6f06dad 405 SUPERFAMILY SSF55021 260 346 2.35E-16 T 28-03-2018 CIG75_RS13945 66a3939b7ee3bc5bb10c82deed08099c 67 Pfam PF06686 Stage III sporulation protein AC/AD protein family 8 62 8.6E-18 T 28-03-2018 IPR025664 Stage III sporulation protein AC/AD family CIG75_RS13945 66a3939b7ee3bc5bb10c82deed08099c 67 TIGRFAM TIGR02848 spore_III_AC: stage III sporulation protein AC 4 66 1.5E-27 T 28-03-2018 IPR009570 Stage III sporulation protein AC CIG75_RS08435 d6f5f21641eec6261d27cad2fe80d9f4 248 Hamap MF_00013 Octanoyltransferase [lipB]. 4 219 31.696 T 28-03-2018 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CIG75_RS08435 d6f5f21641eec6261d27cad2fe80d9f4 248 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 81 134 5.0E-13 T 28-03-2018 CIG75_RS08435 d6f5f21641eec6261d27cad2fe80d9f4 248 SUPERFAMILY SSF55681 4 219 1.91E-62 T 28-03-2018 CIG75_RS08435 d6f5f21641eec6261d27cad2fe80d9f4 248 PIRSF PIRSF016262 1 227 1.2E-55 T 28-03-2018 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CIG75_RS08435 d6f5f21641eec6261d27cad2fe80d9f4 248 Gene3D G3DSA:3.30.930.10 1 217 5.4E-64 T 28-03-2018 CIG75_RS08435 d6f5f21641eec6261d27cad2fe80d9f4 248 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 77 92 - T 28-03-2018 IPR020605 Octanoyltransferase, conserved site GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 CIG75_RS08435 d6f5f21641eec6261d27cad2fe80d9f4 248 TIGRFAM TIGR00214 lipB: lipoyl(octanoyl) transferase 32 216 2.8E-46 T 28-03-2018 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CIG75_RS16445 8de8e41b2d4237c32bdf5e221116ee5f 88 ProDom PD027559 GERMINATION SPORE GERPB PROBABLE PB SPORULATION PB-RELATED 1 48 0.002 T 28-03-2018 IPR024255 Spore germination GerPB CIG75_RS16445 8de8e41b2d4237c32bdf5e221116ee5f 88 Pfam PF10803 Spore germination GerPB 2 37 4.5E-10 T 28-03-2018 IPR024255 Spore germination GerPB CIG75_RS01995 a40dccbb9a49349ccb7bfd4a0e376c27 633 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 420 442 4.2E-16 T 28-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 CIG75_RS01995 a40dccbb9a49349ccb7bfd4a0e376c27 633 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 269 291 4.2E-16 T 28-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 CIG75_RS01995 a40dccbb9a49349ccb7bfd4a0e376c27 633 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 83 103 4.2E-16 T 28-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 CIG75_RS01995 a40dccbb9a49349ccb7bfd4a0e376c27 633 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 498 519 4.2E-16 T 28-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 CIG75_RS01995 a40dccbb9a49349ccb7bfd4a0e376c27 633 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 57 81 4.2E-16 T 28-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 CIG75_RS01995 a40dccbb9a49349ccb7bfd4a0e376c27 633 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 5 623 5.0E-215 T 28-03-2018 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CIG75_RS01995 a40dccbb9a49349ccb7bfd4a0e376c27 633 Pfam PF00361 Proton-conducting membrane transporter 132 426 2.1E-95 T 28-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CIG75_RS01995 a40dccbb9a49349ccb7bfd4a0e376c27 633 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 64 120 2.0E-17 T 28-03-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CIG75_RS01995 a40dccbb9a49349ccb7bfd4a0e376c27 633 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 81 106 2.2E-62 T 28-03-2018 CIG75_RS01995 a40dccbb9a49349ccb7bfd4a0e376c27 633 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 421 440 2.2E-62 T 28-03-2018 CIG75_RS01995 a40dccbb9a49349ccb7bfd4a0e376c27 633 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 229 250 2.2E-62 T 28-03-2018 CIG75_RS01995 a40dccbb9a49349ccb7bfd4a0e376c27 633 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 251 277 2.2E-62 T 28-03-2018 CIG75_RS01995 a40dccbb9a49349ccb7bfd4a0e376c27 633 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 156 177 2.2E-62 T 28-03-2018 CIG75_RS01995 a40dccbb9a49349ccb7bfd4a0e376c27 633 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 319 331 2.2E-62 T 28-03-2018 CIG75_RS01995 a40dccbb9a49349ccb7bfd4a0e376c27 633 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 109 129 2.2E-62 T 28-03-2018 CIG75_RS08445 9de41407ac9de3ff66c1b614c3bea462 1300 TIGRFAM TIGR01746 Thioester-redct: thioester reductase domain 900 1263 8.8E-70 T 28-03-2018 IPR010080 Thioester reductase-like domain CIG75_RS08445 9de41407ac9de3ff66c1b614c3bea462 1300 SUPERFAMILY SSF51735 899 1177 2.77E-35 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS08445 9de41407ac9de3ff66c1b614c3bea462 1300 Pfam PF00501 AMP-binding enzyme 292 684 6.1E-99 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS08445 9de41407ac9de3ff66c1b614c3bea462 1300 ProSitePatterns PS00455 Putative AMP-binding domain signature. 434 445 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS08445 9de41407ac9de3ff66c1b614c3bea462 1300 Pfam PF13193 AMP-binding enzyme C-terminal domain 692 765 1.3E-12 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS08445 9de41407ac9de3ff66c1b614c3bea462 1300 Gene3D G3DSA:3.40.50.980 283 439 2.3E-45 T 28-03-2018 CIG75_RS08445 9de41407ac9de3ff66c1b614c3bea462 1300 Pfam PF00668 Condensation domain 36 272 7.8E-23 T 28-03-2018 IPR001242 Condensation domain CIG75_RS08445 9de41407ac9de3ff66c1b614c3bea462 1300 Pfam PF00550 Phosphopantetheine attachment site 795 854 9.7E-7 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS08445 9de41407ac9de3ff66c1b614c3bea462 1300 Gene3D G3DSA:3.40.50.980 440 591 3.2E-36 T 28-03-2018 CIG75_RS08445 9de41407ac9de3ff66c1b614c3bea462 1300 SUPERFAMILY SSF47336 785 854 1.44E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS08445 9de41407ac9de3ff66c1b614c3bea462 1300 PRINTS PR00154 AMP-binding signature 441 449 7.1E-5 T 28-03-2018 IPR020459 AMP-binding CIG75_RS08445 9de41407ac9de3ff66c1b614c3bea462 1300 PRINTS PR00154 AMP-binding signature 429 440 7.1E-5 T 28-03-2018 IPR020459 AMP-binding CIG75_RS08445 9de41407ac9de3ff66c1b614c3bea462 1300 Gene3D G3DSA:3.40.50.720 894 1204 1.6E-32 T 28-03-2018 CIG75_RS08445 9de41407ac9de3ff66c1b614c3bea462 1300 SUPERFAMILY SSF52777 40 278 1.67E-23 T 28-03-2018 CIG75_RS08445 9de41407ac9de3ff66c1b614c3bea462 1300 Gene3D G3DSA:1.10.1200.10 799 864 2.4E-13 T 28-03-2018 CIG75_RS08445 9de41407ac9de3ff66c1b614c3bea462 1300 SUPERFAMILY SSF56801 252 806 2.75E-161 T 28-03-2018 CIG75_RS08445 9de41407ac9de3ff66c1b614c3bea462 1300 PIRSF PIRSF001617 414 655 1.5E-15 T 28-03-2018 CIG75_RS08445 9de41407ac9de3ff66c1b614c3bea462 1300 PIRSF PIRSF001617 37 424 8.6E-23 T 28-03-2018 CIG75_RS08445 9de41407ac9de3ff66c1b614c3bea462 1300 PIRSF PIRSF001617 728 1225 2.5E-46 T 28-03-2018 CIG75_RS08445 9de41407ac9de3ff66c1b614c3bea462 1300 PIRSF PIRSF001617 649 733 4.5E-22 T 28-03-2018 CIG75_RS08445 9de41407ac9de3ff66c1b614c3bea462 1300 Pfam PF07993 Male sterility protein 902 1143 2.8E-53 T 28-03-2018 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 CIG75_RS08445 9de41407ac9de3ff66c1b614c3bea462 1300 Gene3D G3DSA:2.30.38.10 594 673 6.1E-25 T 28-03-2018 CIG75_RS08445 9de41407ac9de3ff66c1b614c3bea462 1300 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 313 708 1.9E-134 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS08445 9de41407ac9de3ff66c1b614c3bea462 1300 Gene3D G3DSA:3.30.300.30 679 798 1.3E-38 T 28-03-2018 CIG75_RS05530 c9e3daeb1ec6aa718ca308f059996c2d 155 SUPERFAMILY SSF101307 5 152 3.14E-51 T 28-03-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 CIG75_RS05530 c9e3daeb1ec6aa718ca308f059996c2d 155 PIRSF PIRSF019587 1 155 2.8E-66 T 28-03-2018 IPR026038 Putative phosphatidylglycerophosphatase CIG75_RS05530 c9e3daeb1ec6aa718ca308f059996c2d 155 Gene3D G3DSA:1.10.3760.10 1 155 1.8E-56 T 28-03-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 CIG75_RS05530 c9e3daeb1ec6aa718ca308f059996c2d 155 Pfam PF04608 Phosphatidylglycerophosphatase A 7 149 7.7E-20 T 28-03-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 CIG75_RS19730 e2b982078cb22a665d943017821d3a82 206 Gene3D G3DSA:3.40.1370.10 2 145 4.5E-61 T 28-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 CIG75_RS19730 e2b982078cb22a665d943017821d3a82 206 Gene3D G3DSA:3.40.1370.10 146 204 1.8E-15 T 28-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 CIG75_RS19730 e2b982078cb22a665d943017821d3a82 206 SUPERFAMILY SSF52166 1 205 3.14E-85 T 28-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 CIG75_RS19730 e2b982078cb22a665d943017821d3a82 206 Pfam PF00573 Ribosomal protein L4/L1 family 17 203 5.2E-74 T 28-03-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 CIG75_RS19730 e2b982078cb22a665d943017821d3a82 206 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 9 206 37.421 T 28-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS19730 e2b982078cb22a665d943017821d3a82 206 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 17 203 4.7E-84 T 28-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS16055 3e37ed8901092d83b1915b824634ed30 255 Pfam PF01066 CDP-alcohol phosphatidyltransferase 41 107 1.3E-15 T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CIG75_RS16055 3e37ed8901092d83b1915b824634ed30 255 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 85 107 - T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CIG75_RS09900 1c57cff3af27822baa5a1d2a1e656993 285 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 26 85 1.3E-8 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CIG75_RS09900 1c57cff3af27822baa5a1d2a1e656993 285 Gene3D G3DSA:3.40.50.620 1 177 9.6E-82 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CIG75_RS09900 1c57cff3af27822baa5a1d2a1e656993 285 Pfam PF02569 Pantoate-beta-alanine ligase 3 280 5.1E-109 T 28-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 CIG75_RS09900 1c57cff3af27822baa5a1d2a1e656993 285 Hamap MF_00158 Pantothenate synthetase [panC]. 2 282 41.114 T 28-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 CIG75_RS09900 1c57cff3af27822baa5a1d2a1e656993 285 Gene3D G3DSA:3.30.1300.10 179 285 2.4E-31 T 28-03-2018 CIG75_RS09900 1c57cff3af27822baa5a1d2a1e656993 285 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 1 282 1.1E-108 T 28-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 CIG75_RS09900 1c57cff3af27822baa5a1d2a1e656993 285 SUPERFAMILY SSF52374 1 283 7.27E-109 T 28-03-2018 CIG75_RS04240 8f32a110f420dc21b73d6a10fa322812 388 Gene3D G3DSA:1.10.10.10 119 206 5.9E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS04240 8f32a110f420dc21b73d6a10fa322812 388 Pfam PF06224 Winged helix DNA-binding domain 52 359 2.8E-61 T 28-03-2018 IPR009351 Protein of unknown function DUF1006 CIG75_RS04240 8f32a110f420dc21b73d6a10fa322812 388 Gene3D G3DSA:1.10.10.10 207 254 0.044 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS01195 334ec9d8b126a5ba11e09793aa02d340 170 Pfam PF00857 Isochorismatase family 11 142 7.6E-36 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CIG75_RS01195 334ec9d8b126a5ba11e09793aa02d340 170 Gene3D G3DSA:3.40.50.850 7 166 5.5E-40 T 28-03-2018 CIG75_RS01195 334ec9d8b126a5ba11e09793aa02d340 170 SUPERFAMILY SSF52499 6 163 4.06E-47 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CIG75_RS13615 4bee7c72f221221e6c076ac084f7c5d3 117 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 2 105 4.8E-38 T 28-03-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 CIG75_RS13615 4bee7c72f221221e6c076ac084f7c5d3 117 Pfam PF01521 Iron-sulphur cluster biosynthesis 2 101 5.8E-21 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CIG75_RS13615 4bee7c72f221221e6c076ac084f7c5d3 117 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 87 104 - T 28-03-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 CIG75_RS13615 4bee7c72f221221e6c076ac084f7c5d3 117 Gene3D G3DSA:2.60.300.12 1 109 2.0E-40 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CIG75_RS13615 4bee7c72f221221e6c076ac084f7c5d3 117 SUPERFAMILY SSF89360 1 95 1.31E-30 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CIG75_RS14675 e16a02c236376910abff466c11371bc6 168 SUPERFAMILY SSF55729 3 153 4.61E-21 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CIG75_RS14675 e16a02c236376910abff466c11371bc6 168 Pfam PF13302 Acetyltransferase (GNAT) domain 35 144 4.5E-11 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CIG75_RS14675 e16a02c236376910abff466c11371bc6 168 Gene3D G3DSA:3.40.630.30 4 159 2.9E-15 T 28-03-2018 CIG75_RS07025 25201cb16fbd547dd187b6535d08885d 271 Pfam PF13354 Beta-lactamase enzyme family 27 240 5.5E-58 T 28-03-2018 CIG75_RS07025 25201cb16fbd547dd187b6535d08885d 271 Gene3D G3DSA:3.40.710.10 8 270 5.5E-30 T 28-03-2018 CIG75_RS07025 25201cb16fbd547dd187b6535d08885d 271 SUPERFAMILY SSF56601 5 264 1.23E-47 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CIG75_RS09335 a91b7a294959df7ba9e2e30756553c49 228 Gene3D G3DSA:2.40.10.220 102 223 1.4E-17 T 28-03-2018 CIG75_RS09335 a91b7a294959df7ba9e2e30756553c49 228 Pfam PF12945 Flagellar protein YcgR 9 94 2.4E-11 T 28-03-2018 IPR009926 Type III secretion system flagellar brake protein YcgR, N-terminal CIG75_RS09335 a91b7a294959df7ba9e2e30756553c49 228 Pfam PF07238 PilZ domain 103 215 2.3E-10 T 28-03-2018 IPR009875 PilZ domain GO:0035438 CIG75_RS09335 a91b7a294959df7ba9e2e30756553c49 228 Gene3D G3DSA:2.30.110.10 8 101 1.6E-12 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CIG75_RS16885 4916b24be556e00247a13fa45d15d361 184 Gene3D G3DSA:3.40.50.1240 1 184 5.3E-50 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CIG75_RS16885 4916b24be556e00247a13fa45d15d361 184 SMART SM00855 3 151 2.0E-20 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CIG75_RS16885 4916b24be556e00247a13fa45d15d361 184 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 6 15 - T 28-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 CIG75_RS16885 4916b24be556e00247a13fa45d15d361 184 SUPERFAMILY SSF53254 1 181 2.49E-53 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CIG75_RS16885 4916b24be556e00247a13fa45d15d361 184 PIRSF PIRSF000709 2 182 1.1E-12 T 28-03-2018 CIG75_RS16885 4916b24be556e00247a13fa45d15d361 184 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 181 5.0E-50 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CIG75_RS08485 e40387088159dcbaaf90a5ceb54fce01 659 SMART SM00283 382 657 3.1E-73 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CIG75_RS08485 e40387088159dcbaaf90a5ceb54fce01 659 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 445 610 3.8E-42 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CIG75_RS08485 e40387088159dcbaaf90a5ceb54fce01 659 Gene3D G3DSA:1.10.287.950 414 659 3.3E-56 T 28-03-2018 CIG75_RS08485 e40387088159dcbaaf90a5ceb54fce01 659 Gene3D G3DSA:3.30.450.20 32 178 5.9E-10 T 28-03-2018 CIG75_RS08485 e40387088159dcbaaf90a5ceb54fce01 659 SUPERFAMILY SSF103190 52 177 2.86E-10 T 28-03-2018 IPR029151 Periplasmic sensor domain-like CIG75_RS08485 e40387088159dcbaaf90a5ceb54fce01 659 SUPERFAMILY SSF58104 388 657 4.32E-63 T 28-03-2018 CIG75_RS08485 e40387088159dcbaaf90a5ceb54fce01 659 SUPERFAMILY SSF58104 323 355 4.32E-63 T 28-03-2018 CIG75_RS08485 e40387088159dcbaaf90a5ceb54fce01 659 Gene3D G3DSA:1.10.287.950 328 413 9.9E-5 T 28-03-2018 CIG75_RS16360 168b031273a1cd84aacedb8e11b03b4a 202 SUPERFAMILY SSF50475 2 198 1.49E-50 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CIG75_RS16360 168b031273a1cd84aacedb8e11b03b4a 202 Pfam PF01613 Flavin reductase like domain 22 168 2.0E-26 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CIG75_RS16360 168b031273a1cd84aacedb8e11b03b4a 202 SMART SM00903 19 175 1.0E-26 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CIG75_RS16360 168b031273a1cd84aacedb8e11b03b4a 202 Gene3D G3DSA:2.30.110.10 9 191 3.2E-54 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CIG75_RS01815 8241c54b349d32af831f02dec9bb77b1 293 Pfam PF05175 Methyltransferase small domain 103 198 1.0E-13 T 28-03-2018 IPR007848 Methyltransferase small domain GO:0008168 CIG75_RS01815 8241c54b349d32af831f02dec9bb77b1 293 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 192 198 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CIG75_RS01815 8241c54b349d32af831f02dec9bb77b1 293 SUPERFAMILY SSF53335 8 286 1.32E-51 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CIG75_RS01815 8241c54b349d32af831f02dec9bb77b1 293 Gene3D G3DSA:3.40.50.150 88 293 3.2E-43 T 28-03-2018 CIG75_RS01815 8241c54b349d32af831f02dec9bb77b1 293 Gene3D G3DSA:1.10.8.10 7 87 4.8E-21 T 28-03-2018 CIG75_RS01815 8241c54b349d32af831f02dec9bb77b1 293 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 9 291 39.964 T 28-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 CIG75_RS01815 8241c54b349d32af831f02dec9bb77b1 293 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 32 287 3.9E-77 T 28-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 CIG75_RS01815 8241c54b349d32af831f02dec9bb77b1 293 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 8 290 2.3E-67 T 28-03-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 CIG75_RS06035 0f7d24b17b711665867a4140b3103f3e 125 Pfam PF04020 Mycobacterial 4 TMS phage holin, superfamily IV 5 103 1.8E-14 T 28-03-2018 IPR007165 Mycobacterial 4 TMS phage holin, superfamily IV CIG75_RS04060 36dde6934a8094bb9d64cb816020e627 313 SUPERFAMILY SSF103481 202 306 4.97E-7 T 28-03-2018 CIG75_RS04060 36dde6934a8094bb9d64cb816020e627 313 SUPERFAMILY SSF103481 55 151 3.92E-7 T 28-03-2018 CIG75_RS04060 36dde6934a8094bb9d64cb816020e627 313 Pfam PF00892 EamA-like transporter family 15 149 2.7E-12 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CIG75_RS04060 36dde6934a8094bb9d64cb816020e627 313 Pfam PF00892 EamA-like transporter family 168 302 1.8E-15 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CIG75_RS02135 6447d17aafa75c220205c384fc8001d4 562 Pfam PF02517 CAAX protease self-immunity 426 516 2.4E-11 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CIG75_RS08750 46f4096727970b89bbd6a694f828da6e 405 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 32 257 1.3E-56 T 28-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 CIG75_RS08750 46f4096727970b89bbd6a694f828da6e 405 Gene3D G3DSA:2.60.410.10 291 364 6.1E-6 T 28-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CIG75_RS08750 46f4096727970b89bbd6a694f828da6e 405 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 141 154 4.6E-16 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CIG75_RS08750 46f4096727970b89bbd6a694f828da6e 405 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 66 77 4.6E-16 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CIG75_RS08750 46f4096727970b89bbd6a694f828da6e 405 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 114 131 4.6E-16 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CIG75_RS08750 46f4096727970b89bbd6a694f828da6e 405 SUPERFAMILY SSF69189 269 363 1.59E-10 T 28-03-2018 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CIG75_RS08750 46f4096727970b89bbd6a694f828da6e 405 SUPERFAMILY SSF56601 9 277 3.6E-71 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CIG75_RS08750 46f4096727970b89bbd6a694f828da6e 405 Gene3D G3DSA:3.40.710.10 20 290 1.6E-56 T 28-03-2018 CIG75_RS08750 46f4096727970b89bbd6a694f828da6e 405 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 277 364 5.5E-8 T 28-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CIG75_RS08750 46f4096727970b89bbd6a694f828da6e 405 SMART SM00936 277 365 7.3E-8 T 28-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CIG75_RS08280 ce6b688e910e51a50dc8830a0eea827a 355 SUPERFAMILY SSF53092 8 127 5.93E-29 T 28-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal CIG75_RS08280 ce6b688e910e51a50dc8830a0eea827a 355 Gene3D G3DSA:3.40.350.10 1 111 1.2E-33 T 28-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CIG75_RS08280 ce6b688e910e51a50dc8830a0eea827a 355 Pfam PF01321 Creatinase/Prolidase N-terminal domain 4 127 7.2E-30 T 28-03-2018 IPR000587 Creatinase, N-terminal GO:0016787 CIG75_RS08280 ce6b688e910e51a50dc8830a0eea827a 355 SUPERFAMILY SSF55920 88 347 5.63E-79 T 28-03-2018 IPR000994 Peptidase M24 CIG75_RS08280 ce6b688e910e51a50dc8830a0eea827a 355 Gene3D G3DSA:3.90.230.10 112 354 8.3E-76 T 28-03-2018 CIG75_RS08280 ce6b688e910e51a50dc8830a0eea827a 355 PRINTS PR00599 Methionine aminopeptidase-1 signature 306 318 1.6E-6 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CIG75_RS08280 ce6b688e910e51a50dc8830a0eea827a 355 PRINTS PR00599 Methionine aminopeptidase-1 signature 208 224 1.6E-6 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CIG75_RS08280 ce6b688e910e51a50dc8830a0eea827a 355 Pfam PF00557 Metallopeptidase family M24 137 338 1.1E-62 T 28-03-2018 IPR000994 Peptidase M24 CIG75_RS06980 7c6d9463cb50da3e1326d196f136beb1 355 Gene3D G3DSA:3.30.160.60 87 118 6.3E-7 T 28-03-2018 CIG75_RS06980 7c6d9463cb50da3e1326d196f136beb1 355 Pfam PF02618 YceG-like family 54 353 2.1E-81 T 28-03-2018 IPR003770 Endolytic murein transglycosylase CIG75_RS06980 7c6d9463cb50da3e1326d196f136beb1 355 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 29 350 2.9E-74 T 28-03-2018 IPR003770 Endolytic murein transglycosylase CIG75_RS06980 7c6d9463cb50da3e1326d196f136beb1 355 Gene3D G3DSA:3.30.160.60 325 355 4.7E-11 T 28-03-2018 CIG75_RS06980 7c6d9463cb50da3e1326d196f136beb1 355 Hamap MF_02065 Endolytic murein transglycosylase [mltG]. 22 355 32.579 T 28-03-2018 IPR003770 Endolytic murein transglycosylase CIG75_RS05535 da1f53f42dc7c7eb72660525491dbd64 409 SMART SM01274 15 148 3.1E-84 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CIG75_RS05535 da1f53f42dc7c7eb72660525491dbd64 409 Gene3D G3DSA:3.40.50.720 158 406 1.1E-85 T 28-03-2018 CIG75_RS05535 da1f53f42dc7c7eb72660525491dbd64 409 SMART SM00919 160 384 1.1E-136 T 28-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 CIG75_RS05535 da1f53f42dc7c7eb72660525491dbd64 409 Pfam PF03949 Malic enzyme, NAD binding domain 162 383 7.8E-26 T 28-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 CIG75_RS05535 da1f53f42dc7c7eb72660525491dbd64 409 Gene3D G3DSA:3.40.50.10380 3 157 2.1E-42 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CIG75_RS05535 da1f53f42dc7c7eb72660525491dbd64 409 PIRSF PIRSF000106 35 408 1.0E-86 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CIG75_RS05535 da1f53f42dc7c7eb72660525491dbd64 409 SUPERFAMILY SSF51735 160 403 5.32E-85 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS05535 da1f53f42dc7c7eb72660525491dbd64 409 Pfam PF00390 Malic enzyme, N-terminal domain 16 148 8.2E-29 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CIG75_RS05535 da1f53f42dc7c7eb72660525491dbd64 409 PRINTS PR00072 Malic enzyme signature 77 99 1.1E-7 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CIG75_RS05535 da1f53f42dc7c7eb72660525491dbd64 409 PRINTS PR00072 Malic enzyme signature 156 172 1.1E-7 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CIG75_RS05535 da1f53f42dc7c7eb72660525491dbd64 409 PRINTS PR00072 Malic enzyme signature 276 292 1.1E-7 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CIG75_RS05535 da1f53f42dc7c7eb72660525491dbd64 409 ProSitePatterns PS00331 Malic enzymes signature. 156 172 - T 28-03-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 CIG75_RS05535 da1f53f42dc7c7eb72660525491dbd64 409 SUPERFAMILY SSF53223 6 158 1.01E-57 T 28-03-2018 CIG75_RS08110 fb2905fe3176348d36c1f77b952b01dd 562 SUPERFAMILY SSF54791 445 477 2.53E-5 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CIG75_RS08110 fb2905fe3176348d36c1f77b952b01dd 562 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 13 422 2.7E-148 T 28-03-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 CIG75_RS08110 fb2905fe3176348d36c1f77b952b01dd 562 Gene3D G3DSA:3.30.1370.10 430 500 1.7E-4 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CIG75_RS08110 fb2905fe3176348d36c1f77b952b01dd 562 Gene3D G3DSA:2.40.50.140 34 123 3.6E-28 T 28-03-2018 CIG75_RS08110 fb2905fe3176348d36c1f77b952b01dd 562 SUPERFAMILY SSF50249 39 124 2.91E-17 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CIG75_RS08110 fb2905fe3176348d36c1f77b952b01dd 562 SMART SM00316 37 118 1.4E-6 T 28-03-2018 IPR022967 RNA-binding domain, S1 CIG75_RS08110 fb2905fe3176348d36c1f77b952b01dd 562 Pfam PF10150 Ribonuclease E/G family 120 389 1.1E-101 T 28-03-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 CIG75_RS08110 fb2905fe3176348d36c1f77b952b01dd 562 Gene3D G3DSA:2.40.50.140 501 559 3.9E-10 T 28-03-2018 CIG75_RS08110 fb2905fe3176348d36c1f77b952b01dd 562 Pfam PF01938 TRAM domain 498 558 1.0E-6 T 28-03-2018 IPR002792 TRAM domain CIG75_RS05030 39cb77b37b0fee053ba0b0cf6b6afd2c 235 SMART SM00862 156 233 2.6E-19 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CIG75_RS05030 39cb77b37b0fee053ba0b0cf6b6afd2c 235 SUPERFAMILY SSF46894 138 233 8.22E-26 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CIG75_RS05030 39cb77b37b0fee053ba0b0cf6b6afd2c 235 SMART SM00448 5 115 7.3E-47 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CIG75_RS05030 39cb77b37b0fee053ba0b0cf6b6afd2c 235 Gene3D G3DSA:1.10.10.10 129 235 7.1E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS05030 39cb77b37b0fee053ba0b0cf6b6afd2c 235 SUPERFAMILY SSF52172 4 124 6.26E-44 T 28-03-2018 IPR011006 CheY-like superfamily CIG75_RS05030 39cb77b37b0fee053ba0b0cf6b6afd2c 235 Pfam PF00072 Response regulator receiver domain 7 116 3.7E-32 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CIG75_RS05030 39cb77b37b0fee053ba0b0cf6b6afd2c 235 Pfam PF00486 Transcriptional regulatory protein, C terminal 161 232 1.8E-21 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CIG75_RS05030 39cb77b37b0fee053ba0b0cf6b6afd2c 235 Gene3D G3DSA:3.40.50.2300 1 127 1.3E-38 T 28-03-2018 CIG75_RS04620 3f79bad00db976209c093f541e46e49f 67 PRINTS PR00050 Cold shock protein signature 40 58 1.8E-19 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CIG75_RS04620 3f79bad00db976209c093f541e46e49f 67 PRINTS PR00050 Cold shock protein signature 5 20 1.8E-19 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CIG75_RS04620 3f79bad00db976209c093f541e46e49f 67 PRINTS PR00050 Cold shock protein signature 25 34 1.8E-19 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CIG75_RS04620 3f79bad00db976209c093f541e46e49f 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 16 34 - T 28-03-2018 IPR019844 Cold-shock conserved site CIG75_RS04620 3f79bad00db976209c093f541e46e49f 67 SUPERFAMILY SSF50249 3 65 9.06E-25 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CIG75_RS04620 3f79bad00db976209c093f541e46e49f 67 Gene3D G3DSA:2.40.50.140 2 67 1.4E-27 T 28-03-2018 CIG75_RS04620 3f79bad00db976209c093f541e46e49f 67 Pfam PF00313 'Cold-shock' DNA-binding domain 4 66 1.2E-30 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CIG75_RS04620 3f79bad00db976209c093f541e46e49f 67 SMART SM00357 4 67 2.3E-30 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 CIG75_RS04620 3f79bad00db976209c093f541e46e49f 67 PIRSF PIRSF002599 1 67 7.0E-25 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 CIG75_RS20370 59ee0bc89336bb6df936a4aa80b5c775 312 SUPERFAMILY SSF103481 46 150 9.29E-17 T 28-03-2018 CIG75_RS20370 59ee0bc89336bb6df936a4aa80b5c775 312 Pfam PF00892 EamA-like transporter family 13 147 9.8E-25 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CIG75_RS20370 59ee0bc89336bb6df936a4aa80b5c775 312 Pfam PF00892 EamA-like transporter family 161 297 1.4E-25 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CIG75_RS20370 59ee0bc89336bb6df936a4aa80b5c775 312 SUPERFAMILY SSF103481 200 301 1.2E-13 T 28-03-2018 CIG75_RS04740 29d2931590a396f662a084f59a3da763 324 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS04740 29d2931590a396f662a084f59a3da763 324 Gene3D G3DSA:3.40.50.300 10 248 3.4E-62 T 28-03-2018 CIG75_RS04740 29d2931590a396f662a084f59a3da763 324 Pfam PF00005 ABC transporter 30 169 2.5E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS04740 29d2931590a396f662a084f59a3da763 324 SMART SM00382 38 219 6.8E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS04740 29d2931590a396f662a084f59a3da763 324 SUPERFAMILY SSF52540 11 232 4.26E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS09165 ec96e7251bd38d085350e66ce063cac1 152 Hamap MF_00745 Protein SprT-like. 4 148 38.474 T 28-03-2018 IPR023524 Uncharacterised protein family SprT-like CIG75_RS09165 ec96e7251bd38d085350e66ce063cac1 152 SMART SM00731 4 148 1.0E-47 T 28-03-2018 IPR006640 SprT-like CIG75_RS09165 ec96e7251bd38d085350e66ce063cac1 152 Pfam PF10263 SprT-like family 7 100 5.6E-12 T 28-03-2018 IPR006640 SprT-like CIG75_RS07695 a5aad0e2af29deb9af61326333c512c0 412 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 221 258 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CIG75_RS07695 a5aad0e2af29deb9af61326333c512c0 412 Gene3D G3DSA:3.90.1150.10 291 412 1.8E-21 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CIG75_RS07695 a5aad0e2af29deb9af61326333c512c0 412 SUPERFAMILY SSF53383 28 402 2.75E-123 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CIG75_RS07695 a5aad0e2af29deb9af61326333c512c0 412 Gene3D G3DSA:3.40.640.10 62 290 3.0E-67 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CIG75_RS07695 a5aad0e2af29deb9af61326333c512c0 412 PIRSF PIRSF000521 174 405 1.1E-34 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CIG75_RS07695 a5aad0e2af29deb9af61326333c512c0 412 PIRSF PIRSF000521 17 134 0.0011 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CIG75_RS07695 a5aad0e2af29deb9af61326333c512c0 412 PIRSF PIRSF000521 126 156 23.0 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CIG75_RS07695 a5aad0e2af29deb9af61326333c512c0 412 Pfam PF00202 Aminotransferase class-III 31 402 8.6E-105 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CIG75_RS01350 163e1a89188f4a0b24c52158aa3130f2 209 Gene3D G3DSA:3.40.630.30 3 208 1.5E-28 T 28-03-2018 CIG75_RS01350 163e1a89188f4a0b24c52158aa3130f2 209 SUPERFAMILY SSF55729 5 143 4.97E-20 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CIG75_RS01350 163e1a89188f4a0b24c52158aa3130f2 209 Pfam PF00583 Acetyltransferase (GNAT) family 18 143 3.0E-11 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CIG75_RS01445 c301bce8e649d237697c4c6536ec4984 143 Gene3D G3DSA:2.40.128.20 2 138 1.2E-32 T 28-03-2018 IPR012674 Calycin CIG75_RS01445 c301bce8e649d237697c4c6536ec4984 143 SUPERFAMILY SSF50814 6 128 2.26E-24 T 28-03-2018 IPR012674 Calycin CIG75_RS01445 c301bce8e649d237697c4c6536ec4984 143 Pfam PF09148 Domain of unknown function (DUF1934) 10 134 8.7E-31 T 28-03-2018 IPR015231 Protein of unknown function DUF1934 CIG75_RS00235 d0536c82b2111b533f015d71e0d230df 79 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 5 72 2.7E-31 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CIG75_RS00235 d0536c82b2111b533f015d71e0d230df 79 Pfam PF01809 Haemolytic domain 2 68 1.2E-30 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CIG75_RS00235 d0536c82b2111b533f015d71e0d230df 79 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 1 69 25.292 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CIG75_RS00235 d0536c82b2111b533f015d71e0d230df 79 SMART SM01234 1 68 2.9E-45 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CIG75_RS00235 d0536c82b2111b533f015d71e0d230df 79 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 16 68 4.0E-17 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CIG75_RS12050 299aec543dd5cd425bc37574858d08d6 441 SMART SM00382 159 341 1.5E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS12050 299aec543dd5cd425bc37574858d08d6 441 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 147 356 1.7E-74 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CIG75_RS12050 299aec543dd5cd425bc37574858d08d6 441 TIGRFAM TIGR03497 FliI_clade2: flagellar protein export ATPase FliI 24 433 2.0E-200 T 28-03-2018 IPR022425 Flagellar export ATPase FliI, clade 2 GO:0016887|GO:0044780|GO:0071973 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CIG75_RS12050 299aec543dd5cd425bc37574858d08d6 441 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 347 356 - T 28-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CIG75_RS12050 299aec543dd5cd425bc37574858d08d6 441 TIGRFAM TIGR01026 fliI_yscN: ATPase, FliI/YscN family 7 432 1.1E-194 T 28-03-2018 IPR005714 ATPase, type III secretion system, FliI/YscN GO:0005737|GO:0009058|GO:0016887|GO:0030254|GO:0030257 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CIG75_RS12050 299aec543dd5cd425bc37574858d08d6 441 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 26 90 2.6E-6 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CIG75_RS12050 299aec543dd5cd425bc37574858d08d6 441 Gene3D G3DSA:3.40.50.300 92 362 8.1E-88 T 28-03-2018 CIG75_RS12050 299aec543dd5cd425bc37574858d08d6 441 TIGRFAM TIGR03496 FliI_clade1: flagellar protein export ATPase FliI 24 432 4.9E-187 T 28-03-2018 IPR020005 Flagellar export ATPase FliI, clade 1 GO:0016887|GO:0044780|GO:0071973 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CIG75_RS12050 299aec543dd5cd425bc37574858d08d6 441 SUPERFAMILY SSF52540 94 362 4.88E-100 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS00020 388b813aab259ed2b2c48fb1ead60b80 323 TIGRFAM TIGR00678 holB: DNA polymerase III, delta' subunit 11 189 3.6E-60 T 28-03-2018 IPR004622 DNA polymerase III, delta prime subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CIG75_RS00020 388b813aab259ed2b2c48fb1ead60b80 323 Gene3D G3DSA:1.20.272.10 209 323 1.2E-23 T 28-03-2018 CIG75_RS00020 388b813aab259ed2b2c48fb1ead60b80 323 Gene3D G3DSA:3.40.50.300 9 161 6.5E-29 T 28-03-2018 CIG75_RS00020 388b813aab259ed2b2c48fb1ead60b80 323 SUPERFAMILY SSF52540 9 187 1.58E-36 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS00020 388b813aab259ed2b2c48fb1ead60b80 323 Pfam PF13177 DNA polymerase III, delta subunit 10 162 1.6E-55 T 28-03-2018 CIG75_RS00020 388b813aab259ed2b2c48fb1ead60b80 323 Pfam PF09115 DNA polymerase III, delta subunit, C terminal 238 321 2.0E-4 T 28-03-2018 IPR015199 DNA polymerase III, delta subunit, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CIG75_RS10520 2d030921ebfe8512ad5a9dec4e227ef0 409 SUPERFAMILY SSF53756 6 404 1.1E-19 T 28-03-2018 CIG75_RS10520 2d030921ebfe8512ad5a9dec4e227ef0 409 Pfam PF13439 Glycosyltransferase Family 4 51 208 7.4E-10 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CIG75_RS10520 2d030921ebfe8512ad5a9dec4e227ef0 409 Gene3D G3DSA:3.40.50.2000 29 216 8.4E-7 T 28-03-2018 CIG75_RS10520 2d030921ebfe8512ad5a9dec4e227ef0 409 Gene3D G3DSA:3.40.50.2000 217 389 1.1E-7 T 28-03-2018 CIG75_RS16120 95603c36c082e0bb840840bc73e5656c 165 SMART SM00014 51 160 1.9E-20 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CIG75_RS16120 95603c36c082e0bb840840bc73e5656c 165 Pfam PF01569 PAP2 superfamily 51 162 2.9E-19 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CIG75_RS16120 95603c36c082e0bb840840bc73e5656c 165 SUPERFAMILY SSF48317 5 163 1.57E-34 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CIG75_RS16120 95603c36c082e0bb840840bc73e5656c 165 Gene3D G3DSA:1.20.144.10 7 162 2.1E-26 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CIG75_RS09065 8b0cc410f28705a92ca0eff56350bf83 264 SUPERFAMILY SSF103378 23 151 3.14E-10 T 28-03-2018 IPR005656 MmgE/PrpD GO:0016829 CIG75_RS09065 8b0cc410f28705a92ca0eff56350bf83 264 Gene3D G3DSA:1.10.4100.10 1 155 1.9E-6 T 28-03-2018 CIG75_RS17340 c2f8d8c17a0741a6921c300fe9d9fda8 189 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 107 139 2.2E-11 T 28-03-2018 IPR001451 Hexapeptide repeat CIG75_RS17340 c2f8d8c17a0741a6921c300fe9d9fda8 189 Gene3D G3DSA:2.160.10.10 22 159 7.6E-29 T 28-03-2018 CIG75_RS17340 c2f8d8c17a0741a6921c300fe9d9fda8 189 SUPERFAMILY SSF51161 11 159 3.6E-35 T 28-03-2018 IPR011004 Trimeric LpxA-like CIG75_RS17340 c2f8d8c17a0741a6921c300fe9d9fda8 189 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 115 143 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CIG75_RS08705 1b7a86e9031488a371cbcceb80f5132b 249 SUPERFAMILY SSF88659 107 183 7.85E-17 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS08705 1b7a86e9031488a371cbcceb80f5132b 249 Gene3D G3DSA:1.10.601.10 3 103 2.4E-30 T 28-03-2018 CIG75_RS08705 1b7a86e9031488a371cbcceb80f5132b 249 SUPERFAMILY SSF88946 4 103 2.09E-33 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS08705 1b7a86e9031488a371cbcceb80f5132b 249 TIGRFAM TIGR02885 spore_sigF: RNA polymerase sigma-F factor 20 248 1.8E-107 T 28-03-2018 IPR014236 RNA polymerase sigma-F type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS08705 1b7a86e9031488a371cbcceb80f5132b 249 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 218 244 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS08705 1b7a86e9031488a371cbcceb80f5132b 249 Gene3D G3DSA:1.10.10.10 104 156 4.5E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS08705 1b7a86e9031488a371cbcceb80f5132b 249 Gene3D G3DSA:1.10.10.10 188 243 1.3E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS08705 1b7a86e9031488a371cbcceb80f5132b 249 PRINTS PR00046 Major sigma-70 factor signature 218 233 7.0E-11 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS08705 1b7a86e9031488a371cbcceb80f5132b 249 PRINTS PR00046 Major sigma-70 factor signature 59 72 7.0E-11 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS08705 1b7a86e9031488a371cbcceb80f5132b 249 PRINTS PR00046 Major sigma-70 factor signature 83 91 7.0E-11 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS08705 1b7a86e9031488a371cbcceb80f5132b 249 PRINTS PR00046 Major sigma-70 factor signature 233 244 7.0E-11 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS08705 1b7a86e9031488a371cbcceb80f5132b 249 PRINTS PR00046 Major sigma-70 factor signature 201 213 7.0E-11 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS08705 1b7a86e9031488a371cbcceb80f5132b 249 Pfam PF04539 Sigma-70 region 3 113 176 2.9E-11 T 28-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS08705 1b7a86e9031488a371cbcceb80f5132b 249 Pfam PF04542 Sigma-70 region 2 35 102 6.1E-19 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS08705 1b7a86e9031488a371cbcceb80f5132b 249 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 31 248 1.0E-39 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS08705 1b7a86e9031488a371cbcceb80f5132b 249 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 59 72 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS08705 1b7a86e9031488a371cbcceb80f5132b 249 Pfam PF04545 Sigma-70, region 4 197 245 6.2E-15 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS08705 1b7a86e9031488a371cbcceb80f5132b 249 PIRSF PIRSF000770 98 249 3.6E-17 T 28-03-2018 CIG75_RS08705 1b7a86e9031488a371cbcceb80f5132b 249 PIRSF PIRSF000770 1 107 3.6E-18 T 28-03-2018 CIG75_RS08705 1b7a86e9031488a371cbcceb80f5132b 249 SUPERFAMILY SSF88659 169 248 9.53E-18 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS08705 1b7a86e9031488a371cbcceb80f5132b 249 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 30 248 6.8E-86 T 28-03-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS11730 cee59be853d1cc5fa68594ba98aa80eb 200 Gene3D G3DSA:3.40.50.1950 6 200 2.8E-26 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CIG75_RS11730 cee59be853d1cc5fa68594ba98aa80eb 200 Pfam PF02441 Flavoprotein 6 187 4.9E-17 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CIG75_RS11730 cee59be853d1cc5fa68594ba98aa80eb 200 PIRSF PIRSF001390 1 195 6.0E-82 T 28-03-2018 IPR014214 Dipicolinic acid synthetase, subunit B CIG75_RS11730 cee59be853d1cc5fa68594ba98aa80eb 200 SUPERFAMILY SSF52507 6 192 3.66E-27 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CIG75_RS11730 cee59be853d1cc5fa68594ba98aa80eb 200 TIGRFAM TIGR02852 spore_dpaB: dipicolinic acid synthetase, B subunit 6 192 4.8E-90 T 28-03-2018 IPR014214 Dipicolinic acid synthetase, subunit B CIG75_RS09675 2890aef0cc10f982b111444bc71a4f29 257 Pfam PF01739 CheR methyltransferase, SAM binding domain 67 250 3.2E-59 T 28-03-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal CIG75_RS09675 2890aef0cc10f982b111444bc71a4f29 257 Pfam PF03705 CheR methyltransferase, all-alpha domain 2 53 1.9E-12 T 28-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal CIG75_RS09675 2890aef0cc10f982b111444bc71a4f29 257 SUPERFAMILY SSF47757 2 66 1.44E-12 T 28-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal CIG75_RS09675 2890aef0cc10f982b111444bc71a4f29 257 Gene3D G3DSA:3.40.50.150 66 257 7.4E-50 T 28-03-2018 CIG75_RS09675 2890aef0cc10f982b111444bc71a4f29 257 Gene3D G3DSA:1.10.155.10 1 65 4.6E-13 T 28-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal CIG75_RS09675 2890aef0cc10f982b111444bc71a4f29 257 SMART SM00138 1 255 1.2E-95 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CIG75_RS09675 2890aef0cc10f982b111444bc71a4f29 257 PRINTS PR00996 Glutamate methyltransferase family signature 97 117 5.1E-40 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CIG75_RS09675 2890aef0cc10f982b111444bc71a4f29 257 PRINTS PR00996 Glutamate methyltransferase family signature 196 210 5.1E-40 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CIG75_RS09675 2890aef0cc10f982b111444bc71a4f29 257 PRINTS PR00996 Glutamate methyltransferase family signature 23 36 5.1E-40 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CIG75_RS09675 2890aef0cc10f982b111444bc71a4f29 257 PRINTS PR00996 Glutamate methyltransferase family signature 129 145 5.1E-40 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CIG75_RS09675 2890aef0cc10f982b111444bc71a4f29 257 PRINTS PR00996 Glutamate methyltransferase family signature 60 72 5.1E-40 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CIG75_RS09675 2890aef0cc10f982b111444bc71a4f29 257 PRINTS PR00996 Glutamate methyltransferase family signature 215 238 5.1E-40 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CIG75_RS09675 2890aef0cc10f982b111444bc71a4f29 257 SUPERFAMILY SSF53335 67 253 9.33E-51 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CIG75_RS13205 02adadf51d8d9e6c6844c8cf34f0d6fc 94 Gene3D G3DSA:2.30.30.240 1 78 5.9E-19 T 28-03-2018 CIG75_RS13205 02adadf51d8d9e6c6844c8cf34f0d6fc 94 TIGRFAM TIGR02888 spore_YlmC_YmxH: sporulation protein, YlmC/YmxH family 3 76 2.2E-27 T 28-03-2018 IPR014238 Sporulation protein YlmC/YmxH CIG75_RS13205 02adadf51d8d9e6c6844c8cf34f0d6fc 94 SUPERFAMILY SSF50346 1 75 3.92E-17 T 28-03-2018 IPR011033 PRC-barrel-like CIG75_RS13205 02adadf51d8d9e6c6844c8cf34f0d6fc 94 Pfam PF05239 PRC-barrel domain 2 77 5.4E-16 T 28-03-2018 IPR027275 PRC-barrel domain CIG75_RS17840 6df2b506417bae6b79e235d34dfb4e76 249 Gene3D G3DSA:3.30.420.10 84 249 1.7E-33 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CIG75_RS17840 6df2b506417bae6b79e235d34dfb4e76 249 SUPERFAMILY SSF53098 82 246 1.26E-36 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CIG75_RS17840 6df2b506417bae6b79e235d34dfb4e76 249 Pfam PF00665 Integrase core domain 89 202 2.7E-25 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CIG75_RS17840 6df2b506417bae6b79e235d34dfb4e76 249 Pfam PF13276 HTH-like domain 9 66 2.4E-18 T 28-03-2018 IPR025948 HTH-like domain CIG75_RS14605 6df2b506417bae6b79e235d34dfb4e76 249 Gene3D G3DSA:3.30.420.10 84 249 1.7E-33 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CIG75_RS14605 6df2b506417bae6b79e235d34dfb4e76 249 SUPERFAMILY SSF53098 82 246 1.26E-36 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CIG75_RS14605 6df2b506417bae6b79e235d34dfb4e76 249 Pfam PF00665 Integrase core domain 89 202 2.7E-25 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CIG75_RS14605 6df2b506417bae6b79e235d34dfb4e76 249 Pfam PF13276 HTH-like domain 9 66 2.4E-18 T 28-03-2018 IPR025948 HTH-like domain CIG75_RS20355 6df2b506417bae6b79e235d34dfb4e76 249 Gene3D G3DSA:3.30.420.10 84 249 1.7E-33 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CIG75_RS20355 6df2b506417bae6b79e235d34dfb4e76 249 SUPERFAMILY SSF53098 82 246 1.26E-36 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CIG75_RS20355 6df2b506417bae6b79e235d34dfb4e76 249 Pfam PF00665 Integrase core domain 89 202 2.7E-25 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CIG75_RS20355 6df2b506417bae6b79e235d34dfb4e76 249 Pfam PF13276 HTH-like domain 9 66 2.4E-18 T 28-03-2018 IPR025948 HTH-like domain CIG75_RS03985 6df2b506417bae6b79e235d34dfb4e76 249 Gene3D G3DSA:3.30.420.10 84 249 1.7E-33 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CIG75_RS03985 6df2b506417bae6b79e235d34dfb4e76 249 SUPERFAMILY SSF53098 82 246 1.26E-36 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CIG75_RS03985 6df2b506417bae6b79e235d34dfb4e76 249 Pfam PF00665 Integrase core domain 89 202 2.7E-25 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CIG75_RS03985 6df2b506417bae6b79e235d34dfb4e76 249 Pfam PF13276 HTH-like domain 9 66 2.4E-18 T 28-03-2018 IPR025948 HTH-like domain CIG75_RS13240 6df2b506417bae6b79e235d34dfb4e76 249 Gene3D G3DSA:3.30.420.10 84 249 1.7E-33 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CIG75_RS13240 6df2b506417bae6b79e235d34dfb4e76 249 SUPERFAMILY SSF53098 82 246 1.26E-36 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CIG75_RS13240 6df2b506417bae6b79e235d34dfb4e76 249 Pfam PF00665 Integrase core domain 89 202 2.7E-25 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CIG75_RS13240 6df2b506417bae6b79e235d34dfb4e76 249 Pfam PF13276 HTH-like domain 9 66 2.4E-18 T 28-03-2018 IPR025948 HTH-like domain CIG75_RS03085 6df2b506417bae6b79e235d34dfb4e76 249 Gene3D G3DSA:3.30.420.10 84 249 1.7E-33 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CIG75_RS03085 6df2b506417bae6b79e235d34dfb4e76 249 SUPERFAMILY SSF53098 82 246 1.26E-36 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CIG75_RS03085 6df2b506417bae6b79e235d34dfb4e76 249 Pfam PF00665 Integrase core domain 89 202 2.7E-25 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CIG75_RS03085 6df2b506417bae6b79e235d34dfb4e76 249 Pfam PF13276 HTH-like domain 9 66 2.4E-18 T 28-03-2018 IPR025948 HTH-like domain CIG75_RS00035 f8a6c115cb23ac4b22d331d27460edd2 211 Hamap MF_00165 Thymidylate kinase [tmk]. 5 208 30.496 T 28-03-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CIG75_RS00035 f8a6c115cb23ac4b22d331d27460edd2 211 SUPERFAMILY SSF52540 4 207 6.86E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS00035 f8a6c115cb23ac4b22d331d27460edd2 211 Gene3D G3DSA:3.40.50.300 2 206 7.3E-53 T 28-03-2018 CIG75_RS00035 f8a6c115cb23ac4b22d331d27460edd2 211 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 4 200 3.2E-53 T 28-03-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CIG75_RS00035 f8a6c115cb23ac4b22d331d27460edd2 211 Pfam PF02223 Thymidylate kinase 9 200 4.0E-50 T 28-03-2018 CIG75_RS16200 50c7d30b2774f9879c169eba989261c7 145 Pfam PF00575 S1 RNA binding domain 4 74 4.6E-20 T 28-03-2018 IPR003029 S1 domain GO:0003676 CIG75_RS16200 50c7d30b2774f9879c169eba989261c7 145 SMART SM00316 4 74 1.9E-25 T 28-03-2018 IPR022967 RNA-binding domain, S1 CIG75_RS16200 50c7d30b2774f9879c169eba989261c7 145 Gene3D G3DSA:2.40.50.140 6 106 6.3E-27 T 28-03-2018 CIG75_RS16200 50c7d30b2774f9879c169eba989261c7 145 SUPERFAMILY SSF50249 4 81 2.07E-23 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CIG75_RS13660 11b7df555f2b0a3c4d4bcd0dc39c3f54 145 Gene3D G3DSA:3.40.630.30 1 145 8.5E-33 T 28-03-2018 CIG75_RS13660 11b7df555f2b0a3c4d4bcd0dc39c3f54 145 SUPERFAMILY SSF55729 8 144 5.83E-35 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CIG75_RS13660 11b7df555f2b0a3c4d4bcd0dc39c3f54 145 Pfam PF13673 Acetyltransferase (GNAT) domain 25 144 4.0E-19 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CIG75_RS04295 e44404dd411fbb73a4ea512c5f8003e5 188 Pfam PF09860 Uncharacterized protein conserved in bacteria (DUF2087) 112 177 7.6E-22 T 28-03-2018 IPR018656 Domain of unknown function DUF2087 CIG75_RS04295 e44404dd411fbb73a4ea512c5f8003e5 188 Pfam PF01022 Bacterial regulatory protein, arsR family 16 56 8.8E-9 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CIG75_RS04295 e44404dd411fbb73a4ea512c5f8003e5 188 SUPERFAMILY SSF46785 3 184 1.09E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS04295 e44404dd411fbb73a4ea512c5f8003e5 188 SMART SM00418 8 86 1.2E-10 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CIG75_RS04295 e44404dd411fbb73a4ea512c5f8003e5 188 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 42 57 2.9E-6 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CIG75_RS04295 e44404dd411fbb73a4ea512c5f8003e5 188 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 10 25 2.9E-6 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CIG75_RS04295 e44404dd411fbb73a4ea512c5f8003e5 188 Gene3D G3DSA:1.10.10.10 1 96 5.0E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS05285 f9e0de38f094f1c0559a33fb380bcd1b 258 Gene3D G3DSA:3.40.630.40 1 191 2.6E-50 T 28-03-2018 CIG75_RS05285 f9e0de38f094f1c0559a33fb380bcd1b 258 Pfam PF07833 Copper amine oxidase N-terminal domain 223 253 1.3E-5 T 28-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CIG75_RS05285 f9e0de38f094f1c0559a33fb380bcd1b 258 SUPERFAMILY SSF53187 4 187 2.67E-45 T 28-03-2018 CIG75_RS05285 f9e0de38f094f1c0559a33fb380bcd1b 258 SMART SM00646 72 184 1.9E-21 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CIG75_RS05285 f9e0de38f094f1c0559a33fb380bcd1b 258 Gene3D G3DSA:3.30.457.10 228 258 7.6E-4 T 28-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CIG75_RS05285 f9e0de38f094f1c0559a33fb380bcd1b 258 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 6 183 5.9E-44 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CIG75_RS03740 ac40db39a38a9730d4a2655554222659 790 Pfam PF00990 Diguanylate cyclase, GGDEF domain 352 508 2.6E-49 T 28-03-2018 IPR000160 GGDEF domain CIG75_RS03740 ac40db39a38a9730d4a2655554222659 790 Gene3D G3DSA:3.20.20.450 515 772 7.2E-108 T 28-03-2018 IPR001633 EAL domain CIG75_RS03740 ac40db39a38a9730d4a2655554222659 790 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 223 348 1.2E-14 T 28-03-2018 IPR000014 PAS domain CIG75_RS03740 ac40db39a38a9730d4a2655554222659 790 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 101 219 3.6E-15 T 28-03-2018 IPR000014 PAS domain CIG75_RS03740 ac40db39a38a9730d4a2655554222659 790 Pfam PF08448 PAS fold 108 214 6.6E-12 T 28-03-2018 IPR013656 PAS fold-4 CIG75_RS03740 ac40db39a38a9730d4a2655554222659 790 SUPERFAMILY SSF55785 230 343 1.23E-21 T 28-03-2018 IPR000014 PAS domain CIG75_RS03740 ac40db39a38a9730d4a2655554222659 790 SMART SM00086 300 341 1.3E-5 T 28-03-2018 IPR001610 PAC motif CIG75_RS03740 ac40db39a38a9730d4a2655554222659 790 SMART SM00086 172 213 0.29 T 28-03-2018 IPR001610 PAC motif CIG75_RS03740 ac40db39a38a9730d4a2655554222659 790 SUPERFAMILY SSF55785 107 216 9.6E-16 T 28-03-2018 IPR000014 PAS domain CIG75_RS03740 ac40db39a38a9730d4a2655554222659 790 SMART SM00091 225 294 6.4E-6 T 28-03-2018 IPR000014 PAS domain CIG75_RS03740 ac40db39a38a9730d4a2655554222659 790 SMART SM00091 101 167 0.0019 T 28-03-2018 IPR000014 PAS domain CIG75_RS03740 ac40db39a38a9730d4a2655554222659 790 Gene3D G3DSA:3.30.70.270 353 514 2.7E-61 T 28-03-2018 CIG75_RS03740 ac40db39a38a9730d4a2655554222659 790 SUPERFAMILY SSF141868 528 775 1.26E-95 T 28-03-2018 IPR001633 EAL domain CIG75_RS03740 ac40db39a38a9730d4a2655554222659 790 SMART SM00267 341 512 1.5E-67 T 28-03-2018 IPR000160 GGDEF domain CIG75_RS03740 ac40db39a38a9730d4a2655554222659 790 PIRSF PIRSF005925 328 783 2.7E-151 T 28-03-2018 IPR012226 Diguanylate cyclase/phosphodiesterase CIG75_RS03740 ac40db39a38a9730d4a2655554222659 790 PIRSF PIRSF005925 232 350 2.3 T 28-03-2018 IPR012226 Diguanylate cyclase/phosphodiesterase CIG75_RS03740 ac40db39a38a9730d4a2655554222659 790 PIRSF PIRSF005925 98 240 2.8 T 28-03-2018 IPR012226 Diguanylate cyclase/phosphodiesterase CIG75_RS03740 ac40db39a38a9730d4a2655554222659 790 Gene3D G3DSA:3.30.450.20 83 223 1.3E-22 T 28-03-2018 CIG75_RS03740 ac40db39a38a9730d4a2655554222659 790 SUPERFAMILY SSF55073 357 513 1.18E-51 T 28-03-2018 IPR029787 Nucleotide cyclase CIG75_RS03740 ac40db39a38a9730d4a2655554222659 790 SMART SM00052 522 768 1.2E-135 T 28-03-2018 IPR001633 EAL domain CIG75_RS03740 ac40db39a38a9730d4a2655554222659 790 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 348 510 1.2E-42 T 28-03-2018 IPR000160 GGDEF domain CIG75_RS03740 ac40db39a38a9730d4a2655554222659 790 Pfam PF08447 PAS fold 249 334 7.6E-19 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 CIG75_RS03740 ac40db39a38a9730d4a2655554222659 790 Gene3D G3DSA:3.30.450.20 224 352 3.4E-27 T 28-03-2018 CIG75_RS03740 ac40db39a38a9730d4a2655554222659 790 Pfam PF00563 EAL domain 530 763 4.2E-75 T 28-03-2018 IPR001633 EAL domain CIG75_RS19090 1cc325861b69cfffdbe0c4e40131112a 263 Pfam PF06319 DNA repair protein MmcB-like 57 107 2.9E-7 T 28-03-2018 IPR009394 DNA repair protein MmcB-like CIG75_RS04230 599c438d32a31baef19af7ab25313f91 1473 Gene3D G3DSA:1.20.5.50 248 372 0.26 T 28-03-2018 CIG75_RS04230 599c438d32a31baef19af7ab25313f91 1473 Gene3D G3DSA:1.20.5.340 728 845 8.5E-6 T 28-03-2018 CIG75_RS04230 599c438d32a31baef19af7ab25313f91 1473 Gene3D G3DSA:1.20.5.340 376 491 0.026 T 28-03-2018 CIG75_RS04230 599c438d32a31baef19af7ab25313f91 1473 Gene3D G3DSA:1.20.120.330 500 627 1.2E-4 T 28-03-2018 CIG75_RS04230 599c438d32a31baef19af7ab25313f91 1473 Gene3D G3DSA:3.40.50.300 1055 1443 8.2E-4 T 28-03-2018 CIG75_RS12525 7293a3f74019b2b50af52a85daa9582c 68 SMART SM01409 8 60 4.2E-12 T 28-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CIG75_RS12525 7293a3f74019b2b50af52a85daa9582c 68 Pfam PF01192 RNA polymerase Rpb6 9 60 6.1E-14 T 28-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CIG75_RS12525 7293a3f74019b2b50af52a85daa9582c 68 SUPERFAMILY SSF63562 1 62 3.14E-21 T 28-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CIG75_RS12525 7293a3f74019b2b50af52a85daa9582c 68 Gene3D G3DSA:3.90.940.10 1 68 3.0E-21 T 28-03-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CIG75_RS12525 7293a3f74019b2b50af52a85daa9582c 68 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 1 61 14.82 T 28-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CIG75_RS12525 7293a3f74019b2b50af52a85daa9582c 68 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 1 58 9.7E-13 T 28-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CIG75_RS18105 2ff470bcf6e995ac15e4dedb0689ec81 287 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 188 285 6.5E-32 T 28-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CIG75_RS18105 2ff470bcf6e995ac15e4dedb0689ec81 287 SUPERFAMILY SSF51735 4 187 2.37E-53 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS18105 2ff470bcf6e995ac15e4dedb0689ec81 287 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 185 209 - T 28-03-2018 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CIG75_RS18105 2ff470bcf6e995ac15e4dedb0689ec81 287 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 8 186 1.6E-58 T 28-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CIG75_RS18105 2ff470bcf6e995ac15e4dedb0689ec81 287 Gene3D G3DSA:3.40.50.720 5 186 1.8E-52 T 28-03-2018 CIG75_RS18105 2ff470bcf6e995ac15e4dedb0689ec81 287 PIRSF PIRSF000105 1 287 8.8E-86 T 28-03-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 CIG75_RS18105 2ff470bcf6e995ac15e4dedb0689ec81 287 SUPERFAMILY SSF48179 187 287 7.4E-30 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CIG75_RS18105 2ff470bcf6e995ac15e4dedb0689ec81 287 Gene3D G3DSA:1.10.1040.10 187 287 7.9E-31 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CIG75_RS01760 e91bf36a0eddbf65a1f3a453d7b1a292 499 Gene3D G3DSA:2.60.40.1730 62 241 0.0016 T 28-03-2018 CIG75_RS01760 e91bf36a0eddbf65a1f3a453d7b1a292 499 Gene3D G3DSA:1.10.390.10 321 487 1.1E-19 T 28-03-2018 CIG75_RS01760 e91bf36a0eddbf65a1f3a453d7b1a292 499 Pfam PF01433 Peptidase family M1 domain 328 472 9.0E-14 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CIG75_RS01760 e91bf36a0eddbf65a1f3a453d7b1a292 499 SUPERFAMILY SSF55486 267 484 9.67E-28 T 28-03-2018 CIG75_RS09035 b6a1f659f658432bd905f3eefc67589d 502 SUPERFAMILY SSF53187 181 499 4.71E-113 T 28-03-2018 CIG75_RS09035 b6a1f659f658432bd905f3eefc67589d 502 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 22 149 2.4E-22 T 28-03-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CIG75_RS09035 b6a1f659f658432bd905f3eefc67589d 502 Gene3D G3DSA:3.40.630.10 180 502 2.2E-131 T 28-03-2018 CIG75_RS09035 b6a1f659f658432bd905f3eefc67589d 502 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 349 356 - T 28-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CIG75_RS09035 b6a1f659f658432bd905f3eefc67589d 502 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 187 494 1.1E-119 T 28-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CIG75_RS09035 b6a1f659f658432bd905f3eefc67589d 502 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 6 501 34.893 T 28-03-2018 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 CIG75_RS09035 b6a1f659f658432bd905f3eefc67589d 502 PRINTS PR00481 Cytosol aminopeptidase signature 323 344 1.2E-52 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CIG75_RS09035 b6a1f659f658432bd905f3eefc67589d 502 PRINTS PR00481 Cytosol aminopeptidase signature 264 281 1.2E-52 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CIG75_RS09035 b6a1f659f658432bd905f3eefc67589d 502 PRINTS PR00481 Cytosol aminopeptidase signature 286 307 1.2E-52 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CIG75_RS09035 b6a1f659f658432bd905f3eefc67589d 502 PRINTS PR00481 Cytosol aminopeptidase signature 374 389 1.2E-52 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CIG75_RS09035 b6a1f659f658432bd905f3eefc67589d 502 PRINTS PR00481 Cytosol aminopeptidase signature 345 365 1.2E-52 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CIG75_RS09035 b6a1f659f658432bd905f3eefc67589d 502 SUPERFAMILY SSF52949 6 185 1.73E-30 T 28-03-2018 CIG75_RS09035 b6a1f659f658432bd905f3eefc67589d 502 Gene3D G3DSA:3.40.220.10 18 179 2.6E-31 T 28-03-2018 CIG75_RS04465 65f00eb49e8d67998398489c845786c7 295 SMART SM00279 178 213 1.5E-15 T 28-03-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 CIG75_RS04465 65f00eb49e8d67998398489c845786c7 295 SUPERFAMILY SSF88723 5 175 2.7E-48 T 28-03-2018 IPR029060 PIN domain-like CIG75_RS04465 65f00eb49e8d67998398489c845786c7 295 Gene3D G3DSA:1.10.150.20 190 267 7.0E-28 T 28-03-2018 CIG75_RS04465 65f00eb49e8d67998398489c845786c7 295 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 6 174 1.6E-48 T 28-03-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 CIG75_RS04465 65f00eb49e8d67998398489c845786c7 295 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 177 266 6.6E-31 T 28-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 CIG75_RS04465 65f00eb49e8d67998398489c845786c7 295 SMART SM00475 1 266 3.6E-116 T 28-03-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 CIG75_RS04465 65f00eb49e8d67998398489c845786c7 295 Gene3D G3DSA:3.40.50.1010 4 189 3.4E-61 T 28-03-2018 IPR029060 PIN domain-like CIG75_RS04465 65f00eb49e8d67998398489c845786c7 295 SUPERFAMILY SSF47807 176 288 6.13E-31 T 28-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 CIG75_RS20180 23f5bbc1015d3f858a380c39de069125 199 SUPERFAMILY SSF51306 42 114 3.66E-9 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CIG75_RS20180 23f5bbc1015d3f858a380c39de069125 199 Gene3D G3DSA:2.10.109.10 31 134 3.4E-10 T 28-03-2018 CIG75_RS20180 23f5bbc1015d3f858a380c39de069125 199 Pfam PF00717 Peptidase S24-like 46 98 4.2E-7 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CIG75_RS20180 23f5bbc1015d3f858a380c39de069125 199 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 107 118 1.5E-7 T 28-03-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 CIG75_RS20180 23f5bbc1015d3f858a380c39de069125 199 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 47 62 1.5E-7 T 28-03-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 CIG75_RS20180 23f5bbc1015d3f858a380c39de069125 199 TIGRFAM TIGR02228 sigpep_I_arch: signal peptidase I 9 168 1.6E-37 T 28-03-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 CIG75_RS04725 55e8c04e019ef8852af2253ff1c8f428 317 Gene3D G3DSA:3.90.1200.10 97 299 4.0E-18 T 28-03-2018 CIG75_RS04725 55e8c04e019ef8852af2253ff1c8f428 317 SUPERFAMILY SSF56112 15 247 1.02E-26 T 28-03-2018 IPR011009 Protein kinase-like domain CIG75_RS04725 55e8c04e019ef8852af2253ff1c8f428 317 Pfam PF01636 Phosphotransferase enzyme family 21 251 3.4E-16 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CIG75_RS19725 13ecf452f187aa8f55c6856a3e11af1f 96 Pfam PF00276 Ribosomal protein L23 6 88 2.7E-33 T 28-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 CIG75_RS19725 13ecf452f187aa8f55c6856a3e11af1f 96 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 5 95 22.502 T 28-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 CIG75_RS19725 13ecf452f187aa8f55c6856a3e11af1f 96 SUPERFAMILY SSF54189 2 93 3.6E-31 T 28-03-2018 IPR012678 Ribosomal protein L23/L15e core domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS19725 13ecf452f187aa8f55c6856a3e11af1f 96 Gene3D G3DSA:3.30.70.330 2 96 5.5E-33 T 28-03-2018 CIG75_RS19725 13ecf452f187aa8f55c6856a3e11af1f 96 ProSitePatterns PS00050 Ribosomal protein L23 signature. 77 92 - T 28-03-2018 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CIG75_RS16255 041b5422932eff7e27432cd848c330b2 515 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 351 483 6.2E-10 T 28-03-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain CIG75_RS16255 041b5422932eff7e27432cd848c330b2 515 Pfam PF01943 Polysaccharide biosynthesis protein 8 298 3.4E-11 T 28-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 CIG75_RS10185 923b0b2e55ebe48057be12e7ca55d1bf 526 Pfam PF07555 beta-N-acetylglucosaminidase 84 394 9.0E-90 T 28-03-2018 IPR011496 Beta-N-acetylglucosaminidase MetaCyc: PWY-7437 CIG75_RS10185 923b0b2e55ebe48057be12e7ca55d1bf 526 Gene3D G3DSA:1.20.58.460 412 520 9.1E-12 T 28-03-2018 CIG75_RS10185 923b0b2e55ebe48057be12e7ca55d1bf 526 SUPERFAMILY SSF140657 426 490 3.4E-8 T 28-03-2018 CIG75_RS10185 923b0b2e55ebe48057be12e7ca55d1bf 526 SUPERFAMILY SSF51445 82 394 7.37E-84 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CIG75_RS10185 923b0b2e55ebe48057be12e7ca55d1bf 526 Gene3D G3DSA:3.20.20.80 81 411 1.8E-94 T 28-03-2018 CIG75_RS12910 0fbbcecc0eca75eff571df3fb534280a 294 Pfam PF07261 Replication initiation and membrane attachment 179 246 1.6E-10 T 28-03-2018 IPR006343 DnaD domain CIG75_RS12910 0fbbcecc0eca75eff571df3fb534280a 294 TIGRFAM TIGR01446 DnaD_dom: DnaD domain protein 179 245 3.1E-6 T 28-03-2018 IPR006343 DnaD domain CIG75_RS12910 0fbbcecc0eca75eff571df3fb534280a 294 Gene3D G3DSA:1.10.10.630 172 246 6.2E-10 T 28-03-2018 IPR034829 DnaD-like domain CIG75_RS12910 0fbbcecc0eca75eff571df3fb534280a 294 SUPERFAMILY SSF158499 179 241 3.14E-7 T 28-03-2018 IPR006343 DnaD domain CIG75_RS01795 29df08f200394c68d97d7daffd5506ac 203 Pfam PF00265 Thymidine kinase 8 187 4.1E-57 T 28-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 CIG75_RS01795 29df08f200394c68d97d7daffd5506ac 203 SUPERFAMILY SSF57716 142 193 1.92E-15 T 28-03-2018 CIG75_RS01795 29df08f200394c68d97d7daffd5506ac 203 ProSitePatterns PS00603 Thymidine kinase cellular-type signature. 174 187 - T 28-03-2018 IPR020633 Thymidine kinase, conserved site GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 CIG75_RS01795 29df08f200394c68d97d7daffd5506ac 203 PIRSF PIRSF035805 5 199 1.1E-63 T 28-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 CIG75_RS01795 29df08f200394c68d97d7daffd5506ac 203 SUPERFAMILY SSF52540 8 142 1.73E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS01795 29df08f200394c68d97d7daffd5506ac 203 Gene3D G3DSA:3.30.60.20 142 197 5.3E-18 T 28-03-2018 CIG75_RS01795 29df08f200394c68d97d7daffd5506ac 203 Hamap MF_00124 Thymidine kinase [tdk]. 7 190 36.42 T 28-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 CIG75_RS01795 29df08f200394c68d97d7daffd5506ac 203 Gene3D G3DSA:3.40.50.300 7 141 1.3E-45 T 28-03-2018 CIG75_RS03075 da4cc35c72afaf7ae3f5cd6ba52ee1c4 276 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 128 255 4.3E-44 T 28-03-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 CIG75_RS03075 da4cc35c72afaf7ae3f5cd6ba52ee1c4 276 Gene3D G3DSA:3.30.1380.10 106 268 3.4E-38 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CIG75_RS03075 da4cc35c72afaf7ae3f5cd6ba52ee1c4 276 SUPERFAMILY SSF55166 125 262 7.32E-38 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CIG75_RS04880 4862cf4b9767796984499758e99f37f9 159 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 56 153 2.3E-20 T 28-03-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 CIG75_RS04880 4862cf4b9767796984499758e99f37f9 159 Pfam PF03061 Thioesterase superfamily 70 144 2.1E-15 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CIG75_RS04880 4862cf4b9767796984499758e99f37f9 159 Gene3D G3DSA:3.10.129.10 10 154 9.9E-24 T 28-03-2018 CIG75_RS04880 4862cf4b9767796984499758e99f37f9 159 SUPERFAMILY SSF54637 43 157 4.14E-27 T 28-03-2018 IPR029069 HotDog domain CIG75_RS01480 df9ef953c0daddeee1f982f141d3350c 376 Gene3D G3DSA:3.60.15.10 119 372 3.6E-40 T 28-03-2018 IPR001279 Metallo-beta-lactamase CIG75_RS01480 df9ef953c0daddeee1f982f141d3350c 376 SUPERFAMILY SSF52821 2 111 5.63E-23 T 28-03-2018 IPR001763 Rhodanese-like domain CIG75_RS01480 df9ef953c0daddeee1f982f141d3350c 376 SUPERFAMILY SSF56281 118 315 1.26E-42 T 28-03-2018 IPR001279 Metallo-beta-lactamase CIG75_RS01480 df9ef953c0daddeee1f982f141d3350c 376 Gene3D G3DSA:3.40.250.10 5 118 6.4E-25 T 28-03-2018 IPR001763 Rhodanese-like domain CIG75_RS01480 df9ef953c0daddeee1f982f141d3350c 376 Pfam PF00753 Metallo-beta-lactamase superfamily 129 293 6.2E-18 T 28-03-2018 IPR001279 Metallo-beta-lactamase CIG75_RS01480 df9ef953c0daddeee1f982f141d3350c 376 Pfam PF00581 Rhodanese-like domain 8 104 1.0E-12 T 28-03-2018 IPR001763 Rhodanese-like domain CIG75_RS01480 df9ef953c0daddeee1f982f141d3350c 376 SMART SM00849 129 293 1.4E-27 T 28-03-2018 IPR001279 Metallo-beta-lactamase CIG75_RS01480 df9ef953c0daddeee1f982f141d3350c 376 SMART SM00450 7 109 1.4E-17 T 28-03-2018 IPR001763 Rhodanese-like domain CIG75_RS13555 0264e49217544faee5c1769c6f1753dd 396 Gene3D G3DSA:3.30.1050.10 282 388 1.2E-24 T 28-03-2018 IPR003033 SCP2 sterol-binding domain CIG75_RS13555 0264e49217544faee5c1769c6f1753dd 396 SUPERFAMILY SSF55729 3 288 3.37E-49 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CIG75_RS13555 0264e49217544faee5c1769c6f1753dd 396 Gene3D G3DSA:3.40.630.30 1 132 1.3E-11 T 28-03-2018 CIG75_RS13555 0264e49217544faee5c1769c6f1753dd 396 Gene3D G3DSA:3.40.630.30 139 281 1.9E-24 T 28-03-2018 CIG75_RS13555 0264e49217544faee5c1769c6f1753dd 396 Pfam PF13527 Acetyltransferase (GNAT) domain 4 127 2.6E-25 T 28-03-2018 CIG75_RS13555 0264e49217544faee5c1769c6f1753dd 396 SUPERFAMILY SSF55718 299 396 2.94E-18 T 28-03-2018 IPR003033 SCP2 sterol-binding domain CIG75_RS13555 0264e49217544faee5c1769c6f1753dd 396 Pfam PF13530 Sterol carrier protein domain 176 390 1.4E-36 T 28-03-2018 IPR025559 Enhanced intracellular survival protein domain CIG75_RS18530 878335f93d3dfbde28c98e704e7145cf 425 SUPERFAMILY SSF103473 17 409 9.42E-43 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS18530 878335f93d3dfbde28c98e704e7145cf 425 PRINTS PR01988 Putative bacilysin exporter bacE signature 151 172 5.4E-7 T 28-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CIG75_RS18530 878335f93d3dfbde28c98e704e7145cf 425 PRINTS PR01988 Putative bacilysin exporter bacE signature 371 394 5.4E-7 T 28-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CIG75_RS18530 878335f93d3dfbde28c98e704e7145cf 425 PRINTS PR01988 Putative bacilysin exporter bacE signature 178 195 5.4E-7 T 28-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CIG75_RS18530 878335f93d3dfbde28c98e704e7145cf 425 PRINTS PR01988 Putative bacilysin exporter bacE signature 22 44 5.4E-7 T 28-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CIG75_RS18530 878335f93d3dfbde28c98e704e7145cf 425 PRINTS PR01988 Putative bacilysin exporter bacE signature 268 285 5.4E-7 T 28-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CIG75_RS18530 878335f93d3dfbde28c98e704e7145cf 425 Pfam PF05977 Transmembrane secretion effector 15 415 1.2E-37 T 28-03-2018 IPR010290 Transmembrane secretion effector CIG75_RS18530 878335f93d3dfbde28c98e704e7145cf 425 Gene3D G3DSA:1.20.1250.20 10 211 1.5E-19 T 28-03-2018 CIG75_RS18530 878335f93d3dfbde28c98e704e7145cf 425 Gene3D G3DSA:1.20.1250.20 215 408 2.0E-16 T 28-03-2018 CIG75_RS03565 dd61e90aadfd9570f749e9cb56b7aabe 91 Pfam PF06961 Protein of unknown function (DUF1294) 14 68 3.5E-21 T 28-03-2018 IPR010718 Protein of unknown function DUF1294 CIG75_RS03565 dd61e90aadfd9570f749e9cb56b7aabe 91 PIRSF PIRSF002599 2 91 1.4E-9 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 CIG75_RS02465 6fe607d70cfcc175658eebb2e446e461 378 Gene3D G3DSA:3.60.21.10 3 252 4.7E-31 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CIG75_RS02465 6fe607d70cfcc175658eebb2e446e461 378 Pfam PF00149 Calcineurin-like phosphoesterase 7 197 8.8E-11 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CIG75_RS02465 6fe607d70cfcc175658eebb2e446e461 378 SUPERFAMILY SSF56300 7 292 5.41E-43 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CIG75_RS09080 504de4119c35251f3baa5aa1d3694300 223 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 56 76 6.7E-7 T 28-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CIG75_RS09080 504de4119c35251f3baa5aa1d3694300 223 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 33 51 6.7E-7 T 28-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CIG75_RS09080 504de4119c35251f3baa5aa1d3694300 223 SUPERFAMILY SSF53335 20 191 1.11E-20 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CIG75_RS09080 504de4119c35251f3baa5aa1d3694300 223 Gene3D G3DSA:3.40.50.150 81 223 2.6E-17 T 28-03-2018 CIG75_RS09080 504de4119c35251f3baa5aa1d3694300 223 Gene3D G3DSA:3.40.50.150 5 80 1.8E-15 T 28-03-2018 CIG75_RS09080 504de4119c35251f3baa5aa1d3694300 223 Pfam PF01555 DNA methylase 103 218 8.5E-6 T 28-03-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 CIG75_RS09080 504de4119c35251f3baa5aa1d3694300 223 Pfam PF01555 DNA methylase 11 69 1.8E-12 T 28-03-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 CIG75_RS11735 bbb0094a5e05ee8d7010d30527c07f84 292 TIGRFAM TIGR02853 spore_dpaA: dipicolinic acid synthetase, A subunit 5 289 3.2E-117 T 28-03-2018 IPR014215 Dipicolinic acid synthetase subunit A CIG75_RS11735 bbb0094a5e05ee8d7010d30527c07f84 292 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 152 288 3.2E-7 T 28-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CIG75_RS11735 bbb0094a5e05ee8d7010d30527c07f84 292 Gene3D G3DSA:3.40.50.720 1 137 2.2E-8 T 28-03-2018 CIG75_RS11735 bbb0094a5e05ee8d7010d30527c07f84 292 Pfam PF16924 Dipicolinate synthase subunit A N-terminal domain 7 123 1.7E-28 T 28-03-2018 IPR031629 Dipicolinate synthase subunit A, N-terminal CIG75_RS11735 bbb0094a5e05ee8d7010d30527c07f84 292 Gene3D G3DSA:3.40.50.720 138 272 1.9E-21 T 28-03-2018 CIG75_RS11735 bbb0094a5e05ee8d7010d30527c07f84 292 SUPERFAMILY SSF51735 142 271 2.91E-16 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS05545 4035a04f10eea8a402f36a9b14a18ce4 298 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 4 293 39.568 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CIG75_RS05545 4035a04f10eea8a402f36a9b14a18ce4 298 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 175 193 1.6E-37 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CIG75_RS05545 4035a04f10eea8a402f36a9b14a18ce4 298 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 141 155 1.6E-37 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CIG75_RS05545 4035a04f10eea8a402f36a9b14a18ce4 298 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 263 272 1.6E-37 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CIG75_RS05545 4035a04f10eea8a402f36a9b14a18ce4 298 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 212 229 1.6E-37 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CIG75_RS05545 4035a04f10eea8a402f36a9b14a18ce4 298 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 241 252 1.6E-37 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CIG75_RS05545 4035a04f10eea8a402f36a9b14a18ce4 298 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 30 291 3.2E-121 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CIG75_RS05545 4035a04f10eea8a402f36a9b14a18ce4 298 SUPERFAMILY SSF52096 40 291 6.3E-82 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CIG75_RS05545 4035a04f10eea8a402f36a9b14a18ce4 298 Pfam PF01039 Carboxyl transferase domain 83 251 5.1E-18 T 28-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 CIG75_RS05545 4035a04f10eea8a402f36a9b14a18ce4 298 Gene3D G3DSA:3.90.226.10 18 298 1.1E-70 T 28-03-2018 CIG75_RS09365 885f556d17e547e5ddebea228234dbed 236 Gene3D G3DSA:3.60.20.10 5 221 7.5E-86 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CIG75_RS09365 885f556d17e547e5ddebea228234dbed 236 SUPERFAMILY SSF56235 8 220 3.55E-76 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CIG75_RS09365 885f556d17e547e5ddebea228234dbed 236 Pfam PF06267 Family of unknown function (DUF1028) 8 196 1.6E-77 T 28-03-2018 IPR010430 Protein of unknown function DUF1028 CIG75_RS15540 10ba9de3dd7de6096b401cabb593e17e 595 SUPERFAMILY SSF56801 3 280 1.24E-125 T 28-03-2018 CIG75_RS15540 10ba9de3dd7de6096b401cabb593e17e 595 SUPERFAMILY SSF56801 325 584 1.24E-125 T 28-03-2018 CIG75_RS15540 10ba9de3dd7de6096b401cabb593e17e 595 Gene3D G3DSA:3.40.50.980 184 375 1.1E-44 T 28-03-2018 CIG75_RS15540 10ba9de3dd7de6096b401cabb593e17e 595 Pfam PF00501 AMP-binding enzyme 10 454 1.1E-102 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS15540 10ba9de3dd7de6096b401cabb593e17e 595 Gene3D G3DSA:2.30.38.10 376 447 2.7E-19 T 28-03-2018 CIG75_RS15540 10ba9de3dd7de6096b401cabb593e17e 595 ProSitePatterns PS00455 Putative AMP-binding domain signature. 177 188 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS15540 10ba9de3dd7de6096b401cabb593e17e 595 Gene3D G3DSA:3.30.300.30 449 584 1.5E-16 T 28-03-2018 CIG75_RS15540 10ba9de3dd7de6096b401cabb593e17e 595 Gene3D G3DSA:3.40.50.980 1 183 4.8E-42 T 28-03-2018 CIG75_RS02310 23147cd30a7c43f936377db42dd109fa 433 SUPERFAMILY SSF48452 81 183 4.09E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS02310 23147cd30a7c43f936377db42dd109fa 433 Gene3D G3DSA:1.10.150.200 147 200 0.013 T 28-03-2018 CIG75_RS02310 23147cd30a7c43f936377db42dd109fa 433 Gene3D G3DSA:1.10.150.200 201 238 5.0E-6 T 28-03-2018 CIG75_RS02310 23147cd30a7c43f936377db42dd109fa 433 SUPERFAMILY SSF47413 9 68 1.58E-14 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CIG75_RS02310 23147cd30a7c43f936377db42dd109fa 433 SUPERFAMILY SSF48452 186 398 1.93E-15 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS02310 23147cd30a7c43f936377db42dd109fa 433 Gene3D G3DSA:1.25.40.10 280 419 1.7E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS02310 23147cd30a7c43f936377db42dd109fa 433 Gene3D G3DSA:1.10.260.40 3 85 1.7E-15 T 28-03-2018 CIG75_RS02310 23147cd30a7c43f936377db42dd109fa 433 SMART SM00530 13 67 3.2E-12 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS02310 23147cd30a7c43f936377db42dd109fa 433 Pfam PF01381 Helix-turn-helix 14 66 4.4E-10 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS02310 23147cd30a7c43f936377db42dd109fa 433 Pfam PF13424 Tetratricopeptide repeat 197 261 6.9E-8 T 28-03-2018 CIG75_RS02310 23147cd30a7c43f936377db42dd109fa 433 Gene3D G3DSA:1.25.40.10 239 279 0.0017 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS02310 23147cd30a7c43f936377db42dd109fa 433 Gene3D G3DSA:1.25.40.10 86 146 0.0024 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS02310 23147cd30a7c43f936377db42dd109fa 433 SMART SM00028 154 187 460.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS02310 23147cd30a7c43f936377db42dd109fa 433 SMART SM00028 196 229 13.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS02310 23147cd30a7c43f936377db42dd109fa 433 SMART SM00028 314 347 70.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS02310 23147cd30a7c43f936377db42dd109fa 433 SMART SM00028 352 385 280.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS02310 23147cd30a7c43f936377db42dd109fa 433 SMART SM00028 234 267 0.45 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS17465 0d1f8b957bb948096bbea0494e50105e 499 Gene3D G3DSA:1.10.10.10 5 41 0.0017 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS17465 0d1f8b957bb948096bbea0494e50105e 499 Gene3D G3DSA:3.30.420.10 121 318 5.2E-17 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CIG75_RS17465 0d1f8b957bb948096bbea0494e50105e 499 Pfam PF00665 Integrase core domain 127 254 2.5E-14 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CIG75_RS17465 0d1f8b957bb948096bbea0494e50105e 499 SUPERFAMILY SSF53098 124 277 6.32E-8 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CIG75_RS03940 0d1f8b957bb948096bbea0494e50105e 499 Gene3D G3DSA:1.10.10.10 5 41 0.0017 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS03940 0d1f8b957bb948096bbea0494e50105e 499 Gene3D G3DSA:3.30.420.10 121 318 5.2E-17 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CIG75_RS03940 0d1f8b957bb948096bbea0494e50105e 499 Pfam PF00665 Integrase core domain 127 254 2.5E-14 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CIG75_RS03940 0d1f8b957bb948096bbea0494e50105e 499 SUPERFAMILY SSF53098 124 277 6.32E-8 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CIG75_RS00820 0d1f8b957bb948096bbea0494e50105e 499 Gene3D G3DSA:1.10.10.10 5 41 0.0017 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS00820 0d1f8b957bb948096bbea0494e50105e 499 Gene3D G3DSA:3.30.420.10 121 318 5.2E-17 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CIG75_RS00820 0d1f8b957bb948096bbea0494e50105e 499 Pfam PF00665 Integrase core domain 127 254 2.5E-14 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CIG75_RS00820 0d1f8b957bb948096bbea0494e50105e 499 SUPERFAMILY SSF53098 124 277 6.32E-8 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CIG75_RS08270 1914f1df792c9810ca7c4984cd3939fa 250 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 52 244 5.6E-55 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CIG75_RS08270 1914f1df792c9810ca7c4984cd3939fa 250 SMART SM00855 51 201 4.6E-23 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CIG75_RS08270 1914f1df792c9810ca7c4984cd3939fa 250 Gene3D G3DSA:3.40.50.1240 49 250 4.0E-54 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CIG75_RS08270 1914f1df792c9810ca7c4984cd3939fa 250 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 54 63 - T 28-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 CIG75_RS08270 1914f1df792c9810ca7c4984cd3939fa 250 PIRSF PIRSF000709 48 212 5.9E-12 T 28-03-2018 CIG75_RS08270 1914f1df792c9810ca7c4984cd3939fa 250 SUPERFAMILY SSF53254 50 249 2.83E-53 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CIG75_RS00755 e68795d05e23342ed93231314b141f6a 142 Pfam PF01047 MarR family 34 90 1.1E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CIG75_RS00755 e68795d05e23342ed93231314b141f6a 142 SUPERFAMILY SSF46785 16 137 7.98E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS00755 e68795d05e23342ed93231314b141f6a 142 Gene3D G3DSA:1.10.10.10 1 140 3.0E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS00755 e68795d05e23342ed93231314b141f6a 142 SMART SM00347 26 126 4.4E-14 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CIG75_RS08835 7eb421c14e49b9c6e7a4b9592bd8dea3 239 Gene3D G3DSA:3.10.290.10 1 57 2.8E-19 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CIG75_RS08835 7eb421c14e49b9c6e7a4b9592bd8dea3 239 Pfam PF00849 RNA pseudouridylate synthase 63 194 2.5E-24 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CIG75_RS08835 7eb421c14e49b9c6e7a4b9592bd8dea3 239 Gene3D G3DSA:3.30.70.1560 143 206 8.0E-29 T 28-03-2018 CIG75_RS08835 7eb421c14e49b9c6e7a4b9592bd8dea3 239 Gene3D G3DSA:3.30.70.580 58 142 9.3E-24 T 28-03-2018 CIG75_RS08835 7eb421c14e49b9c6e7a4b9592bd8dea3 239 SUPERFAMILY SSF55120 47 235 1.09E-49 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CIG75_RS08835 7eb421c14e49b9c6e7a4b9592bd8dea3 239 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 99 113 - T 28-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 CIG75_RS08835 7eb421c14e49b9c6e7a4b9592bd8dea3 239 Pfam PF01479 S4 domain 2 45 1.6E-13 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CIG75_RS08835 7eb421c14e49b9c6e7a4b9592bd8dea3 239 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 67 224 1.8E-54 T 28-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 CIG75_RS08835 7eb421c14e49b9c6e7a4b9592bd8dea3 239 SUPERFAMILY SSF55174 2 68 2.55E-15 T 28-03-2018 CIG75_RS08835 7eb421c14e49b9c6e7a4b9592bd8dea3 239 SMART SM00363 2 70 5.4E-13 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CIG75_RS06855 dc05e31d540eb9e8acaef6a9233b7f03 409 Gene3D G3DSA:1.20.1250.20 214 408 9.8E-9 T 28-03-2018 CIG75_RS06855 dc05e31d540eb9e8acaef6a9233b7f03 409 Gene3D G3DSA:1.20.1250.20 3 199 2.3E-13 T 28-03-2018 CIG75_RS06855 dc05e31d540eb9e8acaef6a9233b7f03 409 Pfam PF05977 Transmembrane secretion effector 9 403 1.4E-29 T 28-03-2018 IPR010290 Transmembrane secretion effector CIG75_RS06855 dc05e31d540eb9e8acaef6a9233b7f03 409 PRINTS PR01988 Putative bacilysin exporter bacE signature 16 38 2.5E-5 T 28-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CIG75_RS06855 dc05e31d540eb9e8acaef6a9233b7f03 409 PRINTS PR01988 Putative bacilysin exporter bacE signature 79 97 2.5E-5 T 28-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CIG75_RS06855 dc05e31d540eb9e8acaef6a9233b7f03 409 PRINTS PR01988 Putative bacilysin exporter bacE signature 145 166 2.5E-5 T 28-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CIG75_RS06855 dc05e31d540eb9e8acaef6a9233b7f03 409 PRINTS PR01988 Putative bacilysin exporter bacE signature 258 275 2.5E-5 T 28-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CIG75_RS06855 dc05e31d540eb9e8acaef6a9233b7f03 409 SUPERFAMILY SSF103473 11 400 2.09E-32 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS02505 b5d25a57b4490d550e0ceb583ee31c22 414 Gene3D G3DSA:1.20.1250.20 2 193 4.8E-19 T 28-03-2018 CIG75_RS02505 b5d25a57b4490d550e0ceb583ee31c22 414 Pfam PF07690 Major Facilitator Superfamily 16 354 2.2E-27 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CIG75_RS02505 b5d25a57b4490d550e0ceb583ee31c22 414 Gene3D G3DSA:1.20.1250.20 204 392 6.7E-14 T 28-03-2018 CIG75_RS02505 b5d25a57b4490d550e0ceb583ee31c22 414 SUPERFAMILY SSF103473 10 390 4.19E-33 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS09265 1009fea1096a9bfaeab258144cb78e4b 327 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 228 244 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CIG75_RS09265 1009fea1096a9bfaeab258144cb78e4b 327 Gene3D G3DSA:3.40.50.720 4 115 1.2E-33 T 28-03-2018 CIG75_RS09265 1009fea1096a9bfaeab258144cb78e4b 327 SUPERFAMILY SSF52283 4 136 9.64E-36 T 28-03-2018 CIG75_RS09265 1009fea1096a9bfaeab258144cb78e4b 327 SUPERFAMILY SSF51735 102 289 5.42E-62 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS09265 1009fea1096a9bfaeab258144cb78e4b 327 Gene3D G3DSA:3.40.50.720 116 291 1.2E-58 T 28-03-2018 CIG75_RS09265 1009fea1096a9bfaeab258144cb78e4b 327 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 111 288 2.0E-64 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CIG75_RS09265 1009fea1096a9bfaeab258144cb78e4b 327 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 7 320 3.1E-31 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CIG75_RS02220 812638c20ed91a68f48f869f23464195 398 Pfam PF07730 Histidine kinase 179 246 1.8E-17 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CIG75_RS02220 812638c20ed91a68f48f869f23464195 398 PIRSF PIRSF003169 2 381 2.4E-138 T 28-03-2018 IPR016381 Signal transduction histidine kinase, DegS GO:0000155|GO:0000160|GO:0004673 CIG75_RS02220 812638c20ed91a68f48f869f23464195 398 SUPERFAMILY SSF55874 248 372 3.27E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS02220 812638c20ed91a68f48f869f23464195 398 Gene3D G3DSA:3.30.565.10 9 376 6.3E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS02220 812638c20ed91a68f48f869f23464195 398 Pfam PF05384 Sensor protein DegS 11 169 1.8E-51 T 28-03-2018 IPR008595 Sensor DegS GO:0007165|GO:0016301 CIG75_RS16765 f21c33bd746be2a206317146be73f3bd 133 SUPERFAMILY SSF47413 3 71 2.3E-18 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CIG75_RS16765 f21c33bd746be2a206317146be73f3bd 133 SMART SM00530 8 63 4.1E-16 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS16765 f21c33bd746be2a206317146be73f3bd 133 Gene3D G3DSA:1.10.3100.10 1 129 7.4E-22 T 28-03-2018 IPR027910 YdiL-like domain CIG75_RS16765 f21c33bd746be2a206317146be73f3bd 133 Pfam PF01381 Helix-turn-helix 10 63 6.6E-16 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS14635 9083d3ea68e4fa838c44f9db6a9b59c5 232 Gene3D G3DSA:3.40.50.150 2 163 1.7E-19 T 28-03-2018 CIG75_RS14635 9083d3ea68e4fa838c44f9db6a9b59c5 232 SUPERFAMILY SSF53335 8 143 1.26E-12 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CIG75_RS14635 9083d3ea68e4fa838c44f9db6a9b59c5 232 PIRSF PIRSF018637 2 230 1.1E-73 T 28-03-2018 IPR006901 tRNA methyltransferase TrmK GO:0016429 CIG75_RS14635 9083d3ea68e4fa838c44f9db6a9b59c5 232 Pfam PF04816 tRNA (adenine(22)-N(1))-methyltransferase 22 218 3.9E-60 T 28-03-2018 IPR006901 tRNA methyltransferase TrmK GO:0016429 CIG75_RS03495 e49fa84effa5375c6a1b8d88ec99452d 162 Pfam PF13404 AsnC-type helix-turn-helix domain 16 56 2.8E-16 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CIG75_RS03495 e49fa84effa5375c6a1b8d88ec99452d 162 SMART SM00344 16 122 2.8E-41 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CIG75_RS03495 e49fa84effa5375c6a1b8d88ec99452d 162 Pfam PF01037 Lrp/AsnC ligand binding domain 84 152 3.6E-13 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CIG75_RS03495 e49fa84effa5375c6a1b8d88ec99452d 162 Gene3D G3DSA:1.10.10.10 14 67 2.1E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS03495 e49fa84effa5375c6a1b8d88ec99452d 162 SUPERFAMILY SSF54909 77 155 9.52E-15 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CIG75_RS03495 e49fa84effa5375c6a1b8d88ec99452d 162 SUPERFAMILY SSF46785 15 75 1.34E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS03495 e49fa84effa5375c6a1b8d88ec99452d 162 ProSitePatterns PS00519 AsnC-type HTH domain signature. 34 60 - T 28-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site CIG75_RS03495 e49fa84effa5375c6a1b8d88ec99452d 162 Gene3D G3DSA:3.30.70.920 68 162 7.9E-20 T 28-03-2018 CIG75_RS03495 e49fa84effa5375c6a1b8d88ec99452d 162 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 16 32 4.2E-14 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CIG75_RS03495 e49fa84effa5375c6a1b8d88ec99452d 162 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 43 62 4.2E-14 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CIG75_RS03495 e49fa84effa5375c6a1b8d88ec99452d 162 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 43 4.2E-14 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CIG75_RS16515 64105380537917ab655ef68e1298f7f1 581 Pfam PF00672 HAMP domain 224 272 3.1E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CIG75_RS16515 64105380537917ab655ef68e1298f7f1 581 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 432 461 1.8E-21 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CIG75_RS16515 64105380537917ab655ef68e1298f7f1 581 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 30 55 1.8E-21 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CIG75_RS16515 64105380537917ab655ef68e1298f7f1 581 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 403 430 1.8E-21 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CIG75_RS16515 64105380537917ab655ef68e1298f7f1 581 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 350 533 1.1E-45 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CIG75_RS16515 64105380537917ab655ef68e1298f7f1 581 SMART SM00304 223 276 1.2E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CIG75_RS16515 64105380537917ab655ef68e1298f7f1 581 Gene3D G3DSA:1.10.287.950 340 581 7.9E-58 T 28-03-2018 CIG75_RS16515 64105380537917ab655ef68e1298f7f1 581 SUPERFAMILY SSF58104 248 278 1.83E-72 T 28-03-2018 CIG75_RS16515 64105380537917ab655ef68e1298f7f1 581 SUPERFAMILY SSF58104 311 580 1.83E-72 T 28-03-2018 CIG75_RS16515 64105380537917ab655ef68e1298f7f1 581 Gene3D G3DSA:1.10.287.950 222 339 7.8E-8 T 28-03-2018 CIG75_RS16515 64105380537917ab655ef68e1298f7f1 581 SMART SM00283 305 580 3.9E-86 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CIG75_RS16515 64105380537917ab655ef68e1298f7f1 581 Gene3D G3DSA:1.20.120.30 35 195 2.1E-11 T 28-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain CIG75_RS16515 64105380537917ab655ef68e1298f7f1 581 Pfam PF12729 Four helix bundle sensory module for signal transduction 19 192 3.1E-26 T 28-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain CIG75_RS04630 e70b73a277a6f78b73716a7f05488def 217 TIGRFAM TIGR03717 R_switched_YjbE: integral membrane protein, YjbE family 8 179 8.5E-55 T 28-03-2018 IPR022301 Integral membrane protein YjbE CIG75_RS04630 e70b73a277a6f78b73716a7f05488def 217 Pfam PF03741 Integral membrane protein TerC family 9 179 7.4E-41 T 28-03-2018 IPR005496 Integral membrane protein TerC GO:0016021 CIG75_RS17770 39e16cb05c18729e072b5144fcbf0e44 73 Pfam PF07872 Protein of unknown function (DUF1659) 9 50 1.3E-15 T 28-03-2018 IPR012454 Protein of unknown function DUF1659 CIG75_RS12620 435cd8c7c249842a2e863e17f7ca7b4e 432 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 75 86 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CIG75_RS12620 435cd8c7c249842a2e863e17f7ca7b4e 432 SUPERFAMILY SSF46548 20 102 7.59E-21 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CIG75_RS12620 435cd8c7c249842a2e863e17f7ca7b4e 432 PIRSF PIRSF000139 11 432 1.7E-132 T 28-03-2018 CIG75_RS12620 435cd8c7c249842a2e863e17f7ca7b4e 432 Pfam PF02754 Cysteine-rich domain 322 407 6.6E-17 T 28-03-2018 IPR004017 Cysteine-rich domain CIG75_RS12620 435cd8c7c249842a2e863e17f7ca7b4e 432 Pfam PF02754 Cysteine-rich domain 193 276 3.6E-18 T 28-03-2018 IPR004017 Cysteine-rich domain CIG75_RS12620 435cd8c7c249842a2e863e17f7ca7b4e 432 Gene3D G3DSA:3.40.50.720 190 396 1.9E-4 T 28-03-2018 CIG75_RS12620 435cd8c7c249842a2e863e17f7ca7b4e 432 Pfam PF13183 4Fe-4S dicluster domain 21 89 1.3E-13 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CIG75_RS12620 435cd8c7c249842a2e863e17f7ca7b4e 432 Gene3D G3DSA:1.10.1060.10 7 112 1.6E-18 T 28-03-2018 CIG75_RS05310 93623f812023e4451d39abe84730794f 203 SUPERFAMILY SSF48498 74 190 8.26E-12 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CIG75_RS05310 93623f812023e4451d39abe84730794f 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 4.9E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CIG75_RS05310 93623f812023e4451d39abe84730794f 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 9 22 4.9E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CIG75_RS05310 93623f812023e4451d39abe84730794f 203 Gene3D G3DSA:1.10.10.60 4 47 2.0E-18 T 28-03-2018 CIG75_RS05310 93623f812023e4451d39abe84730794f 203 Gene3D G3DSA:1.10.357.10 48 190 5.7E-13 T 28-03-2018 CIG75_RS05310 93623f812023e4451d39abe84730794f 203 SUPERFAMILY SSF46689 3 60 2.51E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CIG75_RS05310 93623f812023e4451d39abe84730794f 203 ProSitePatterns PS01081 TetR-type HTH domain signature. 21 52 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CIG75_RS05310 93623f812023e4451d39abe84730794f 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 55 5.8E-18 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CIG75_RS00970 9af5bd25536ce296629c67cca3dc2943 283 SUPERFAMILY SSF46689 217 267 2.2E-6 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CIG75_RS00970 9af5bd25536ce296629c67cca3dc2943 283 SMART SM00342 180 265 3.4E-15 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CIG75_RS00970 9af5bd25536ce296629c67cca3dc2943 283 Pfam PF12833 Helix-turn-helix domain 187 266 6.0E-19 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CIG75_RS00970 9af5bd25536ce296629c67cca3dc2943 283 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 218 261 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CIG75_RS00970 9af5bd25536ce296629c67cca3dc2943 283 Gene3D G3DSA:1.10.10.60 221 268 1.9E-9 T 28-03-2018 CIG75_RS00970 9af5bd25536ce296629c67cca3dc2943 283 Gene3D G3DSA:1.10.10.60 160 220 4.1E-8 T 28-03-2018 CIG75_RS00970 9af5bd25536ce296629c67cca3dc2943 283 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 167 210 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CIG75_RS12500 0592351c66e796d0d6f49f93a832f4f0 446 Pfam PF01029 NusB family 4 125 6.7E-32 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CIG75_RS12500 0592351c66e796d0d6f49f93a832f4f0 446 TIGRFAM TIGR00563 rsmB: 16S rRNA (cytosine(967)-C(5))-methyltransferase 6 446 4.0E-144 T 28-03-2018 IPR004573 rRNA small subunit methyltransferase B GO:0006364|GO:0008649 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CIG75_RS12500 0592351c66e796d0d6f49f93a832f4f0 446 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 428 445 6.5E-32 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CIG75_RS12500 0592351c66e796d0d6f49f93a832f4f0 446 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 229 243 6.5E-32 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CIG75_RS12500 0592351c66e796d0d6f49f93a832f4f0 446 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 258 268 6.5E-32 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CIG75_RS12500 0592351c66e796d0d6f49f93a832f4f0 446 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 374 390 6.5E-32 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CIG75_RS12500 0592351c66e796d0d6f49f93a832f4f0 446 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 324 336 6.5E-32 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CIG75_RS12500 0592351c66e796d0d6f49f93a832f4f0 446 Gene3D G3DSA:3.30.70.1170 181 237 1.6E-16 T 28-03-2018 CIG75_RS12500 0592351c66e796d0d6f49f93a832f4f0 446 Gene3D G3DSA:3.40.50.150 238 446 1.9E-65 T 28-03-2018 CIG75_RS12500 0592351c66e796d0d6f49f93a832f4f0 446 Pfam PF01189 16S rRNA methyltransferase RsmB/F 247 444 5.8E-66 T 28-03-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CIG75_RS12500 0592351c66e796d0d6f49f93a832f4f0 446 SUPERFAMILY SSF53335 140 446 1.46E-82 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CIG75_RS12500 0592351c66e796d0d6f49f93a832f4f0 446 SUPERFAMILY SSF48013 4 155 8.18E-37 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CIG75_RS12500 0592351c66e796d0d6f49f93a832f4f0 446 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 323 334 - T 28-03-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CIG75_RS12500 0592351c66e796d0d6f49f93a832f4f0 446 Gene3D G3DSA:1.10.940.10 2 146 3.1E-33 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CIG75_RS16235 0d342dfbe28c790377ad4e843dc57691 124 Hamap MF_00818 NADPH-dependent 7-cyano-7-deazaguanine reductase [queF]. 1 124 48.431 T 28-03-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 CIG75_RS16235 0d342dfbe28c790377ad4e843dc57691 124 TIGRFAM TIGR03139 QueF-II: 7-cyano-7-deazaguanine reductase 7 116 3.1E-51 T 28-03-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 CIG75_RS16235 0d342dfbe28c790377ad4e843dc57691 124 Pfam PF14489 QueF-like protein 40 116 5.4E-33 T 28-03-2018 IPR029500 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF GO:0008616|GO:0033739 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 CIG75_RS16235 0d342dfbe28c790377ad4e843dc57691 124 Gene3D G3DSA:3.30.1130.10 2 121 3.6E-33 T 28-03-2018 CIG75_RS16235 0d342dfbe28c790377ad4e843dc57691 124 SUPERFAMILY SSF55620 4 113 6.89E-28 T 28-03-2018 CIG75_RS16235 0d342dfbe28c790377ad4e843dc57691 124 PIRSF PIRSF027377 1 123 4.2E-51 T 28-03-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 CIG75_RS09045 f184b9e303bb10a0b8b6c4157e28a30e 254 Gene3D G3DSA:2.40.10.10 26 144 1.3E-31 T 28-03-2018 CIG75_RS09045 f184b9e303bb10a0b8b6c4157e28a30e 254 Gene3D G3DSA:2.40.10.10 145 240 2.0E-38 T 28-03-2018 CIG75_RS09045 f184b9e303bb10a0b8b6c4157e28a30e 254 Pfam PF13365 Trypsin-like peptidase domain 77 214 2.0E-32 T 28-03-2018 CIG75_RS09045 f184b9e303bb10a0b8b6c4157e28a30e 254 SUPERFAMILY SSF50494 28 243 5.98E-58 T 28-03-2018 IPR009003 Peptidase S1, PA clan CIG75_RS09045 f184b9e303bb10a0b8b6c4157e28a30e 254 PRINTS PR00834 HtrA/DegQ protease family signature 108 128 1.2E-38 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CIG75_RS09045 f184b9e303bb10a0b8b6c4157e28a30e 254 PRINTS PR00834 HtrA/DegQ protease family signature 149 173 1.2E-38 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CIG75_RS09045 f184b9e303bb10a0b8b6c4157e28a30e 254 PRINTS PR00834 HtrA/DegQ protease family signature 86 98 1.2E-38 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CIG75_RS09045 f184b9e303bb10a0b8b6c4157e28a30e 254 PRINTS PR00834 HtrA/DegQ protease family signature 207 224 1.2E-38 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CIG75_RS09045 f184b9e303bb10a0b8b6c4157e28a30e 254 PRINTS PR00834 HtrA/DegQ protease family signature 185 202 1.2E-38 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CIG75_RS07515 bd9d53e8a8c04c2dc19afa5ad01121ca 164 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 53 129 1.1E-9 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CIG75_RS07515 bd9d53e8a8c04c2dc19afa5ad01121ca 164 Gene3D G3DSA:3.10.20.30 40 158 3.3E-22 T 28-03-2018 IPR012675 Beta-grasp domain CIG75_RS07515 bd9d53e8a8c04c2dc19afa5ad01121ca 164 SUPERFAMILY SSF54292 46 138 5.51E-21 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CIG75_RS09220 7d4fa5d0146cc3876da33bbac6691aff 342 TIGRFAM TIGR01208 rmlA_long: glucose-1-phosphate thymidylyltransferase 2 335 3.5E-99 T 28-03-2018 IPR005908 Glucose-1-phosphate thymidylyltransferase, long form CIG75_RS09220 7d4fa5d0146cc3876da33bbac6691aff 342 Gene3D G3DSA:3.90.550.10 1 236 1.9E-57 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CIG75_RS09220 7d4fa5d0146cc3876da33bbac6691aff 342 SUPERFAMILY SSF53448 1 289 2.48E-70 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CIG75_RS09220 7d4fa5d0146cc3876da33bbac6691aff 342 Pfam PF07959 L-fucokinase 207 327 1.4E-8 T 28-03-2018 IPR012887 L-fucokinase GO:0016772 Reactome: R-HSA-6787639 CIG75_RS09220 7d4fa5d0146cc3876da33bbac6691aff 342 Gene3D G3DSA:2.160.10.10 237 334 5.0E-10 T 28-03-2018 CIG75_RS09220 7d4fa5d0146cc3876da33bbac6691aff 342 Pfam PF00483 Nucleotidyl transferase 2 224 1.1E-42 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CIG75_RS03475 5f8aee3b3398be8f488a9c490591b4a7 330 SMART SM00382 33 233 1.9E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS03475 5f8aee3b3398be8f488a9c490591b4a7 330 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 233 319 3.4E-27 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CIG75_RS03475 5f8aee3b3398be8f488a9c490591b4a7 330 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS03475 5f8aee3b3398be8f488a9c490591b4a7 330 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 299 9.9E-20 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CIG75_RS03475 5f8aee3b3398be8f488a9c490591b4a7 330 Pfam PF00005 ABC transporter 25 183 2.0E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS03475 5f8aee3b3398be8f488a9c490591b4a7 330 Gene3D G3DSA:3.40.50.300 1 330 1.1E-78 T 28-03-2018 CIG75_RS03475 5f8aee3b3398be8f488a9c490591b4a7 330 SUPERFAMILY SSF52540 32 311 2.39E-67 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS01485 58826e787887d55d449dc46482c8c134 74 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 7 31 - T 28-03-2018 IPR001455 TusA-like domain CIG75_RS01485 58826e787887d55d449dc46482c8c134 74 SUPERFAMILY SSF64307 3 74 6.67E-23 T 28-03-2018 IPR001455 TusA-like domain CIG75_RS01485 58826e787887d55d449dc46482c8c134 74 Gene3D G3DSA:3.30.110.40 1 74 1.6E-25 T 28-03-2018 IPR001455 TusA-like domain CIG75_RS01485 58826e787887d55d449dc46482c8c134 74 Pfam PF01206 Sulfurtransferase TusA 6 74 2.3E-23 T 28-03-2018 IPR001455 TusA-like domain CIG75_RS15835 1c6972c1693ac354d33faf61628a984a 235 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 8 195 16.534 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CIG75_RS15835 1c6972c1693ac354d33faf61628a984a 235 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 6 195 4.0E-45 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CIG75_RS15835 1c6972c1693ac354d33faf61628a984a 235 Pfam PF02660 Glycerol-3-phosphate acyltransferase 12 186 5.2E-39 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CIG75_RS15835 1c6972c1693ac354d33faf61628a984a 235 SMART SM01207 11 187 5.6E-50 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CIG75_RS16040 ad84cf90dfea2b5899d634ce37db27b1 64 Gene3D G3DSA:1.10.10.10 3 59 1.1E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS00135 cae385860db1e275bbf5ee2a7bcbb4ac 379 SUPERFAMILY SSF48208 2 377 1.02E-66 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CIG75_RS00135 cae385860db1e275bbf5ee2a7bcbb4ac 379 Gene3D G3DSA:1.50.10.10 1 314 1.6E-67 T 28-03-2018 CIG75_RS00135 cae385860db1e275bbf5ee2a7bcbb4ac 379 Gene3D G3DSA:1.50.10.10 315 378 3.9E-12 T 28-03-2018 CIG75_RS00135 cae385860db1e275bbf5ee2a7bcbb4ac 379 Pfam PF00723 Glycosyl hydrolases family 15 2 323 3.9E-14 T 28-03-2018 IPR011613 Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family Reactome: R-HSA-70221 CIG75_RS08135 991cebfb1a7db26d332b7babd06489e1 428 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 2 328 4.5E-140 T 28-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 CIG75_RS08135 991cebfb1a7db26d332b7babd06489e1 428 SUPERFAMILY SSF52540 160 334 6.19E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS08135 991cebfb1a7db26d332b7babd06489e1 428 TIGRFAM TIGR03595 Obg_CgtA_exten: Obg family GTPase CgtA, C-terminal extension 360 426 4.4E-23 T 28-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 CIG75_RS08135 991cebfb1a7db26d332b7babd06489e1 428 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 161 181 2.1E-35 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CIG75_RS08135 991cebfb1a7db26d332b7babd06489e1 428 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 227 245 2.1E-35 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CIG75_RS08135 991cebfb1a7db26d332b7babd06489e1 428 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 182 200 2.1E-35 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CIG75_RS08135 991cebfb1a7db26d332b7babd06489e1 428 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 210 225 2.1E-35 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CIG75_RS08135 991cebfb1a7db26d332b7babd06489e1 428 Hamap MF_01454 GTPase Obg [obg]. 1 329 47.842 T 28-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 CIG75_RS08135 991cebfb1a7db26d332b7babd06489e1 428 PIRSF PIRSF002401 1 375 2.3E-140 T 28-03-2018 IPR035101 GTP-binding protein, Obg-type CIG75_RS08135 991cebfb1a7db26d332b7babd06489e1 428 SUPERFAMILY SSF102741 358 428 2.09E-20 T 28-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 CIG75_RS08135 991cebfb1a7db26d332b7babd06489e1 428 ProSitePatterns PS00905 GTP1/OBG family signature. 212 225 - T 28-03-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 CIG75_RS08135 991cebfb1a7db26d332b7babd06489e1 428 Gene3D G3DSA:2.70.210.12 1 155 2.9E-60 T 28-03-2018 IPR006169 GTP1/OBG domain CIG75_RS08135 991cebfb1a7db26d332b7babd06489e1 428 Pfam PF09269 Domain of unknown function (DUF1967) 359 426 1.0E-25 T 28-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 CIG75_RS08135 991cebfb1a7db26d332b7babd06489e1 428 Pfam PF01018 GTP1/OBG 3 157 8.7E-61 T 28-03-2018 IPR006169 GTP1/OBG domain CIG75_RS08135 991cebfb1a7db26d332b7babd06489e1 428 Pfam PF01926 50S ribosome-binding GTPase 160 283 2.3E-22 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CIG75_RS08135 991cebfb1a7db26d332b7babd06489e1 428 SUPERFAMILY SSF82051 1 157 4.05E-56 T 28-03-2018 IPR006169 GTP1/OBG domain CIG75_RS08135 991cebfb1a7db26d332b7babd06489e1 428 Gene3D G3DSA:3.40.50.300 158 337 1.5E-33 T 28-03-2018 CIG75_RS03960 04add20fc447dfea750162a8208cea19 180 SUPERFAMILY SSF46689 80 127 1.39E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CIG75_RS03960 04add20fc447dfea750162a8208cea19 180 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 161 177 3.9E-7 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CIG75_RS03960 04add20fc447dfea750162a8208cea19 180 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 146 161 3.9E-7 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CIG75_RS03960 04add20fc447dfea750162a8208cea19 180 SMART SM00342 94 177 1.5E-30 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CIG75_RS03960 04add20fc447dfea750162a8208cea19 180 Pfam PF02805 Metal binding domain of Ada 5 68 2.9E-26 T 28-03-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 CIG75_RS03960 04add20fc447dfea750162a8208cea19 180 SUPERFAMILY SSF57884 2 71 1.96E-27 T 28-03-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 CIG75_RS03960 04add20fc447dfea750162a8208cea19 180 Gene3D G3DSA:1.10.10.60 75 128 3.7E-13 T 28-03-2018 CIG75_RS03960 04add20fc447dfea750162a8208cea19 180 Gene3D G3DSA:1.10.10.60 129 179 1.2E-13 T 28-03-2018 CIG75_RS03960 04add20fc447dfea750162a8208cea19 180 PIRSF PIRSF000408 1 180 8.2E-61 T 28-03-2018 IPR016220 Methylphosphotriester-DNA alkyltransferase, AdaA CIG75_RS03960 04add20fc447dfea750162a8208cea19 180 Gene3D G3DSA:3.40.10.10 1 70 3.0E-22 T 28-03-2018 IPR035451 Ada-like domain CIG75_RS03960 04add20fc447dfea750162a8208cea19 180 Pfam PF12833 Helix-turn-helix domain 103 178 8.2E-21 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CIG75_RS03960 04add20fc447dfea750162a8208cea19 180 SUPERFAMILY SSF46689 130 178 2.11E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CIG75_RS01875 80056d57f6d507e18c618626732a95fe 156 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 3 145 1.7E-56 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CIG75_RS01875 80056d57f6d507e18c618626732a95fe 156 Gene3D G3DSA:3.40.1400.10 1 154 4.1E-69 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CIG75_RS01875 80056d57f6d507e18c618626732a95fe 156 PIRSF PIRSF005384 1 147 6.4E-59 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CIG75_RS01875 80056d57f6d507e18c618626732a95fe 156 SUPERFAMILY SSF89623 1 144 8.5E-60 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CIG75_RS01875 80056d57f6d507e18c618626732a95fe 156 Pfam PF02502 Ribose/Galactose Isomerase 3 140 2.9E-58 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CIG75_RS01875 80056d57f6d507e18c618626732a95fe 156 TIGRFAM TIGR01120 rpiB: ribose 5-phosphate isomerase B 2 144 2.7E-54 T 28-03-2018 IPR004785 Ribose 5-phosphate isomerase B GO:0004751|GO:0006098 CIG75_RS07990 0ad41ad913d243c66b9ef6893821d543 227 Pfam PF08713 DNA alkylation repair enzyme 6 215 6.9E-18 T 28-03-2018 IPR014825 DNA alkylation repair enzyme CIG75_RS07990 0ad41ad913d243c66b9ef6893821d543 227 Gene3D G3DSA:1.20.1660.10 2 112 3.4E-5 T 28-03-2018 CIG75_RS07990 0ad41ad913d243c66b9ef6893821d543 227 SUPERFAMILY SSF48371 1 225 6.33E-59 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 CIG75_RS19310 55dbd0aa9e845af505683124ca4bad33 174 Pfam PF09671 Spore coat protein (Spore_GerQ) 72 146 1.6E-37 T 28-03-2018 IPR014099 Spore coat protein GerQ CIG75_RS19310 55dbd0aa9e845af505683124ca4bad33 174 PIRSF PIRSF038931 8 155 2.1E-44 T 28-03-2018 IPR014099 Spore coat protein GerQ CIG75_RS19310 55dbd0aa9e845af505683124ca4bad33 174 TIGRFAM TIGR02728 spore_gerQ: spore coat protein GerQ 71 148 1.4E-36 T 28-03-2018 IPR014099 Spore coat protein GerQ CIG75_RS19625 d31df236774f25c177010adedff0c630 248 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 165 183 - T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CIG75_RS19625 d31df236774f25c177010adedff0c630 248 Pfam PF00557 Metallopeptidase family M24 12 239 7.2E-56 T 28-03-2018 IPR000994 Peptidase M24 CIG75_RS19625 d31df236774f25c177010adedff0c630 248 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 5 247 5.3E-100 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CIG75_RS19625 d31df236774f25c177010adedff0c630 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 159 171 9.0E-23 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CIG75_RS19625 d31df236774f25c177010adedff0c630 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 89 105 9.0E-23 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CIG75_RS19625 d31df236774f25c177010adedff0c630 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 190 202 9.0E-23 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CIG75_RS19625 d31df236774f25c177010adedff0c630 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 67 80 9.0E-23 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CIG75_RS19625 d31df236774f25c177010adedff0c630 248 SUPERFAMILY SSF55920 1 247 3.53E-91 T 28-03-2018 IPR000994 Peptidase M24 CIG75_RS19625 d31df236774f25c177010adedff0c630 248 Hamap MF_01974 Methionine aminopeptidase [map]. 2 248 42.587 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CIG75_RS19625 d31df236774f25c177010adedff0c630 248 Gene3D G3DSA:3.90.230.10 1 248 6.1E-85 T 28-03-2018 CIG75_RS05085 5c330af2c85aedf525d8ad3a3a88f952 271 SUPERFAMILY SSF56300 44 270 4.41E-29 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CIG75_RS05085 5c330af2c85aedf525d8ad3a3a88f952 271 Gene3D G3DSA:3.60.21.10 41 268 2.3E-22 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CIG75_RS05085 5c330af2c85aedf525d8ad3a3a88f952 271 Pfam PF00149 Calcineurin-like phosphoesterase 44 206 2.8E-10 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CIG75_RS00150 230dc0ecae2192b02906ef0a2332f0d1 416 Gene3D G3DSA:3.40.710.10 40 296 2.1E-44 T 28-03-2018 CIG75_RS00150 230dc0ecae2192b02906ef0a2332f0d1 416 SUPERFAMILY SSF56601 16 297 1.51E-74 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CIG75_RS00150 230dc0ecae2192b02906ef0a2332f0d1 416 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 297 386 6.8E-10 T 28-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CIG75_RS00150 230dc0ecae2192b02906ef0a2332f0d1 416 Gene3D G3DSA:2.60.410.10 297 386 1.0E-14 T 28-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CIG75_RS00150 230dc0ecae2192b02906ef0a2332f0d1 416 SMART SM00936 297 386 2.9E-13 T 28-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CIG75_RS00150 230dc0ecae2192b02906ef0a2332f0d1 416 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 48 277 1.8E-73 T 28-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 CIG75_RS00150 230dc0ecae2192b02906ef0a2332f0d1 416 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 135 152 7.2E-15 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CIG75_RS00150 230dc0ecae2192b02906ef0a2332f0d1 416 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 82 93 7.2E-15 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CIG75_RS00150 230dc0ecae2192b02906ef0a2332f0d1 416 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 162 175 7.2E-15 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CIG75_RS00150 230dc0ecae2192b02906ef0a2332f0d1 416 SUPERFAMILY SSF69189 289 385 9.61E-13 T 28-03-2018 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CIG75_RS07260 80b5b59ca9e8fb07af448038e0fbbe9f 319 Pfam PF09565 NgoFVII restriction endonuclease 17 279 1.6E-43 T 28-03-2018 IPR019065 Restriction endonuclease, type II, NgoFVII CIG75_RS07260 80b5b59ca9e8fb07af448038e0fbbe9f 319 Gene3D G3DSA:3.30.870.10 26 164 6.3E-6 T 28-03-2018 CIG75_RS11495 71528f6f6076241c3784ac55eb2b0f03 462 Pfam PF14398 YheC/D like ATP-grasp 198 452 4.0E-71 T 28-03-2018 IPR026838 Endospore coat-associated protein YheC/D CIG75_RS11495 71528f6f6076241c3784ac55eb2b0f03 462 Gene3D G3DSA:3.30.1490.20 225 300 1.2E-8 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CIG75_RS11495 71528f6f6076241c3784ac55eb2b0f03 462 SUPERFAMILY SSF56059 302 430 8.56E-20 T 28-03-2018 CIG75_RS11495 71528f6f6076241c3784ac55eb2b0f03 462 SUPERFAMILY SSF56059 221 269 8.56E-20 T 28-03-2018 CIG75_RS11495 71528f6f6076241c3784ac55eb2b0f03 462 Gene3D G3DSA:3.30.470.20 301 438 1.5E-16 T 28-03-2018 CIG75_RS07620 ec7697033df4d2d9da714c6832fe7e35 269 Gene3D G3DSA:3.30.565.10 135 263 5.8E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS07620 ec7697033df4d2d9da714c6832fe7e35 269 SUPERFAMILY SSF55874 145 261 5.31E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS07620 ec7697033df4d2d9da714c6832fe7e35 269 Pfam PF07730 Histidine kinase 80 132 1.4E-9 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CIG75_RS15600 af6dd1d2dc9bde63c8bca6b7d232a45f 87 Pfam PF12652 CotJB protein 11 86 1.6E-26 T 28-03-2018 IPR024207 Spore coat assembly protein CotJB, domain CIG75_RS15600 af6dd1d2dc9bde63c8bca6b7d232a45f 87 PIRSF PIRSF010606 1 87 4.6E-37 T 28-03-2018 IPR016571 Spore coat assembly protein CotJB CIG75_RS08075 84376a10b4cde2be1a860c1de730c6c8 283 PIRSF PIRSF038471 1 282 1.7E-54 T 28-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 CIG75_RS08075 84376a10b4cde2be1a860c1de730c6c8 283 TIGRFAM TIGR00219 mreC: rod shape-determining protein MreC 3 277 5.7E-46 T 28-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 CIG75_RS08075 84376a10b4cde2be1a860c1de730c6c8 283 Pfam PF04085 rod shape-determining protein MreC 115 275 3.8E-39 T 28-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 CIG75_RS05360 8dd21ece93cd6da10fe5fcf6447b377c 152 SUPERFAMILY SSF75217 1 150 1.31E-45 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CIG75_RS05360 8dd21ece93cd6da10fe5fcf6447b377c 152 Gene3D G3DSA:3.40.1280.10 1 152 2.8E-40 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CIG75_RS05360 8dd21ece93cd6da10fe5fcf6447b377c 152 Pfam PF00588 SpoU rRNA Methylase family 2 139 1.5E-35 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CIG75_RS05360 8dd21ece93cd6da10fe5fcf6447b377c 152 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 1 149 34.778 T 28-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 CIG75_RS05360 8dd21ece93cd6da10fe5fcf6447b377c 152 PIRSF PIRSF029256 1 152 6.3E-65 T 28-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 CIG75_RS05360 8dd21ece93cd6da10fe5fcf6447b377c 152 TIGRFAM TIGR00185 tRNA_yibK_trmL: tRNA (cytidine(34)-2'-O)-methyltransferase 1 151 1.6E-58 T 28-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 CIG75_RS14825 8ce4defec87a4aa44ed32725cd97aadf 345 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 1 333 31.722 T 28-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 CIG75_RS14825 8ce4defec87a4aa44ed32725cd97aadf 345 SUPERFAMILY SSF46785 1 83 6.81E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS14825 8ce4defec87a4aa44ed32725cd97aadf 345 Gene3D G3DSA:3.30.450.40 205 345 4.3E-47 T 28-03-2018 IPR029016 GAF domain-like CIG75_RS14825 8ce4defec87a4aa44ed32725cd97aadf 345 Gene3D G3DSA:1.10.10.10 1 84 2.7E-32 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS14825 8ce4defec87a4aa44ed32725cd97aadf 345 PIRSF PIRSF005485 1 344 1.4E-118 T 28-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 CIG75_RS14825 8ce4defec87a4aa44ed32725cd97aadf 345 Pfam PF01628 HrcA protein C terminal domain 104 326 1.0E-67 T 28-03-2018 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 CIG75_RS14825 8ce4defec87a4aa44ed32725cd97aadf 345 Gene3D G3DSA:3.30.390.60 128 204 4.2E-22 T 28-03-2018 IPR023120 Winged helix-turn-helix transcription repressor, HrcA, inserted dimerising domain CIG75_RS14825 8ce4defec87a4aa44ed32725cd97aadf 345 Pfam PF03444 Winged helix-turn-helix transcription repressor, HrcA DNA-binding 1 72 5.9E-5 T 28-03-2018 IPR005104 Winged helix-turn-helix transcription repressor, HrcA DNA-binding domain GO:0003677|GO:0006355 CIG75_RS14825 8ce4defec87a4aa44ed32725cd97aadf 345 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 3 338 1.9E-105 T 28-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 CIG75_RS14825 8ce4defec87a4aa44ed32725cd97aadf 345 SUPERFAMILY SSF55781 71 342 7.45E-66 T 28-03-2018 IPR029016 GAF domain-like CIG75_RS18285 b9bdadd0ac436c806bc512d83fa9a261 814 Gene3D G3DSA:2.70.20.10 351 476 3.8E-38 T 28-03-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 CIG75_RS18285 b9bdadd0ac436c806bc512d83fa9a261 814 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 187 205 1.8E-33 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CIG75_RS18285 b9bdadd0ac436c806bc512d83fa9a261 814 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 102 115 1.8E-33 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CIG75_RS18285 b9bdadd0ac436c806bc512d83fa9a261 814 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 319 328 1.8E-33 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CIG75_RS18285 b9bdadd0ac436c806bc512d83fa9a261 814 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 504 518 1.8E-33 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CIG75_RS18285 b9bdadd0ac436c806bc512d83fa9a261 814 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 396 412 1.8E-33 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CIG75_RS18285 b9bdadd0ac436c806bc512d83fa9a261 814 SUPERFAMILY SSF57783 697 733 1.6E-12 T 28-03-2018 CIG75_RS18285 b9bdadd0ac436c806bc512d83fa9a261 814 SUPERFAMILY SSF57783 607 641 3.91E-5 T 28-03-2018 CIG75_RS18285 b9bdadd0ac436c806bc512d83fa9a261 814 Hamap MF_00952 DNA topoisomerase 1 [topA]. 28 713 51.163 T 28-03-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 CIG75_RS18285 b9bdadd0ac436c806bc512d83fa9a261 814 Pfam PF01751 Toprim domain 30 138 1.1E-29 T 28-03-2018 IPR006171 TOPRIM domain CIG75_RS18285 b9bdadd0ac436c806bc512d83fa9a261 814 Gene3D G3DSA:3.30.65.10 740 795 4.1E-12 T 28-03-2018 CIG75_RS18285 b9bdadd0ac436c806bc512d83fa9a261 814 Gene3D G3DSA:3.30.65.10 596 648 1.2E-9 T 28-03-2018 CIG75_RS18285 b9bdadd0ac436c806bc512d83fa9a261 814 Gene3D G3DSA:3.30.65.10 683 739 7.5E-16 T 28-03-2018 CIG75_RS18285 b9bdadd0ac436c806bc512d83fa9a261 814 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 30 637 7.9E-230 T 28-03-2018 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 CIG75_RS18285 b9bdadd0ac436c806bc512d83fa9a261 814 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 306 328 - T 28-03-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 CIG75_RS18285 b9bdadd0ac436c806bc512d83fa9a261 814 SMART SM00493 28 128 2.1E-33 T 28-03-2018 IPR006171 TOPRIM domain CIG75_RS18285 b9bdadd0ac436c806bc512d83fa9a261 814 Pfam PF01131 DNA topoisomerase 153 578 1.3E-125 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CIG75_RS18285 b9bdadd0ac436c806bc512d83fa9a261 814 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 753 783 6.1E-10 T 28-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 CIG75_RS18285 b9bdadd0ac436c806bc512d83fa9a261 814 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 700 735 4.5E-14 T 28-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 CIG75_RS18285 b9bdadd0ac436c806bc512d83fa9a261 814 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 609 641 7.0E-9 T 28-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 CIG75_RS18285 b9bdadd0ac436c806bc512d83fa9a261 814 SUPERFAMILY SSF57783 747 787 3.4E-9 T 28-03-2018 CIG75_RS18285 b9bdadd0ac436c806bc512d83fa9a261 814 SUPERFAMILY SSF56712 28 618 1.96E-190 T 28-03-2018 IPR023405 DNA topoisomerase, type IA, core domain CIG75_RS18285 b9bdadd0ac436c806bc512d83fa9a261 814 SMART SM00437 269 541 1.5E-116 T 28-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 CIG75_RS18285 b9bdadd0ac436c806bc512d83fa9a261 814 Gene3D G3DSA:3.40.50.140 27 154 5.2E-41 T 28-03-2018 CIG75_RS18285 b9bdadd0ac436c806bc512d83fa9a261 814 SMART SM00436 129 217 7.1E-49 T 28-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 CIG75_RS18285 b9bdadd0ac436c806bc512d83fa9a261 814 Gene3D G3DSA:1.10.460.10 160 348 5.8E-46 T 28-03-2018 CIG75_RS18285 b9bdadd0ac436c806bc512d83fa9a261 814 Gene3D G3DSA:1.10.460.10 477 595 3.0E-24 T 28-03-2018 CIG75_RS03825 cee2628beb54c1850c6903cea9e88a35 96 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 2 95 23.726 T 28-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CIG75_RS03825 cee2628beb54c1850c6903cea9e88a35 96 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 3 95 1.6E-26 T 28-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CIG75_RS03825 cee2628beb54c1850c6903cea9e88a35 96 SUPERFAMILY SSF141000 2 93 1.7E-28 T 28-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CIG75_RS03825 cee2628beb54c1850c6903cea9e88a35 96 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 19 90 2.9E-19 T 28-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CIG75_RS16565 4f35f02caafc7cb8ccfa940361d7eee0 192 Pfam PF06962 Putative rRNA methylase 48 187 8.8E-46 T 28-03-2018 IPR010719 Putative rRNA methylase CIG75_RS16565 4f35f02caafc7cb8ccfa940361d7eee0 192 Gene3D G3DSA:3.40.50.150 4 192 1.4E-19 T 28-03-2018 CIG75_RS16565 4f35f02caafc7cb8ccfa940361d7eee0 192 SUPERFAMILY SSF53335 17 160 3.86E-22 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CIG75_RS00920 f6239828078c79da636607e9afb1ad28 113 TIGRFAM TIGR00686 phnA: putative alkylphosphonate utilization operon protein PhnA 3 112 7.3E-52 T 28-03-2018 IPR004624 PhnA protein CIG75_RS00920 f6239828078c79da636607e9afb1ad28 113 Pfam PF03831 PhnA domain 46 113 1.3E-34 T 28-03-2018 IPR013988 PhnA protein, C-terminal CIG75_RS00920 f6239828078c79da636607e9afb1ad28 113 SUPERFAMILY SSF82057 41 113 1.05E-29 T 28-03-2018 CIG75_RS00920 f6239828078c79da636607e9afb1ad28 113 Gene3D G3DSA:2.30.30.40 45 112 9.2E-38 T 28-03-2018 CIG75_RS00920 f6239828078c79da636607e9afb1ad28 113 Gene3D G3DSA:2.20.25.10 3 40 9.2E-15 T 28-03-2018 CIG75_RS00920 f6239828078c79da636607e9afb1ad28 113 Pfam PF08274 PhnA Zinc-Ribbon 3 32 9.4E-14 T 28-03-2018 IPR013987 PhnA protein, N-terminal CIG75_RS00920 f6239828078c79da636607e9afb1ad28 113 SUPERFAMILY SSF57783 3 36 2.04E-13 T 28-03-2018 CIG75_RS04475 fb1c0c9b9999de697ba35eb19c52cc9f 638 SUPERFAMILY SSF48371 545 622 4.03E-18 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 CIG75_RS04475 fb1c0c9b9999de697ba35eb19c52cc9f 638 Gene3D G3DSA:1.25.40.70 529 605 1.9E-15 T 28-03-2018 CIG75_RS04475 fb1c0c9b9999de697ba35eb19c52cc9f 638 Gene3D G3DSA:3.40.50.300 1 200 3.1E-32 T 28-03-2018 CIG75_RS04475 fb1c0c9b9999de697ba35eb19c52cc9f 638 Pfam PF13646 HEAT repeats 547 629 5.5E-15 T 28-03-2018 CIG75_RS04475 fb1c0c9b9999de697ba35eb19c52cc9f 638 ProSitePatterns PS00690 DEAH-box subfamily ATP-dependent helicases signature. 133 142 - T 28-03-2018 IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site CIG75_RS04475 fb1c0c9b9999de697ba35eb19c52cc9f 638 Gene3D G3DSA:3.40.50.300 202 487 1.0E-46 T 28-03-2018 CIG75_RS04475 fb1c0c9b9999de697ba35eb19c52cc9f 638 Pfam PF16124 RecQ zinc-binding 437 483 5.6E-6 T 28-03-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain CIG75_RS04475 fb1c0c9b9999de697ba35eb19c52cc9f 638 SMART SM00490 244 327 1.1E-24 T 28-03-2018 IPR001650 Helicase, C-terminal CIG75_RS04475 fb1c0c9b9999de697ba35eb19c52cc9f 638 SMART SM00487 13 210 1.9E-31 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CIG75_RS04475 fb1c0c9b9999de697ba35eb19c52cc9f 638 Pfam PF00270 DEAD/DEAH box helicase 20 181 3.6E-19 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CIG75_RS04475 fb1c0c9b9999de697ba35eb19c52cc9f 638 SMART SM00567 E-Z type HEAT repeats 589 618 1.5E-4 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CIG75_RS04475 fb1c0c9b9999de697ba35eb19c52cc9f 638 SMART SM00567 E-Z type HEAT repeats 558 587 4.4 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CIG75_RS04475 fb1c0c9b9999de697ba35eb19c52cc9f 638 Pfam PF00271 Helicase conserved C-terminal domain 218 326 7.9E-17 T 28-03-2018 IPR001650 Helicase, C-terminal CIG75_RS04475 fb1c0c9b9999de697ba35eb19c52cc9f 638 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 8 348 1.8E-120 T 28-03-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 CIG75_RS04475 fb1c0c9b9999de697ba35eb19c52cc9f 638 SUPERFAMILY SSF52540 57 348 4.82E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS08450 b2bda45a92b781fc649af8e27ec0e8a4 327 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 2 324 2.7E-114 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CIG75_RS08450 b2bda45a92b781fc649af8e27ec0e8a4 327 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 10 19 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CIG75_RS08450 b2bda45a92b781fc649af8e27ec0e8a4 327 SUPERFAMILY SSF52374 2 324 1.83E-98 T 28-03-2018 CIG75_RS08450 b2bda45a92b781fc649af8e27ec0e8a4 327 Gene3D G3DSA:3.40.50.620 2 187 5.8E-74 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CIG75_RS08450 b2bda45a92b781fc649af8e27ec0e8a4 327 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 14 30 8.3E-28 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CIG75_RS08450 b2bda45a92b781fc649af8e27ec0e8a4 327 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 139 160 8.3E-28 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CIG75_RS08450 b2bda45a92b781fc649af8e27ec0e8a4 327 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 64 83 8.3E-28 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CIG75_RS08450 b2bda45a92b781fc649af8e27ec0e8a4 327 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 192 202 8.3E-28 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CIG75_RS08450 b2bda45a92b781fc649af8e27ec0e8a4 327 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 1 325 42.296 T 28-03-2018 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 CIG75_RS08450 b2bda45a92b781fc649af8e27ec0e8a4 327 Gene3D G3DSA:1.10.240.10 188 307 2.2E-28 T 28-03-2018 CIG75_RS08450 b2bda45a92b781fc649af8e27ec0e8a4 327 Pfam PF00579 tRNA synthetases class I (W and Y) 3 276 1.3E-79 T 28-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 CIG75_RS16665 75a2722fb25fd7f19f14bc90b26b66b1 477 SUPERFAMILY SSF56024 266 461 1.05E-45 T 28-03-2018 CIG75_RS16665 75a2722fb25fd7f19f14bc90b26b66b1 477 SMART SM00155 390 417 4.2E-5 T 28-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CIG75_RS16665 75a2722fb25fd7f19f14bc90b26b66b1 477 SMART SM00155 214 241 9.9E-6 T 28-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CIG75_RS16665 75a2722fb25fd7f19f14bc90b26b66b1 477 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 3 477 1.3E-161 T 28-03-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 CIG75_RS16665 75a2722fb25fd7f19f14bc90b26b66b1 477 Pfam PF13396 Phospholipase_D-nuclease N-terminal 13 54 8.0E-10 T 28-03-2018 IPR027379 Cardiolipin synthase N-terminal CIG75_RS16665 75a2722fb25fd7f19f14bc90b26b66b1 477 SUPERFAMILY SSF56024 99 307 6.91E-58 T 28-03-2018 CIG75_RS16665 75a2722fb25fd7f19f14bc90b26b66b1 477 Gene3D G3DSA:3.30.870.10 303 467 2.7E-29 T 28-03-2018 CIG75_RS16665 75a2722fb25fd7f19f14bc90b26b66b1 477 Hamap MF_01916 Cardiolipin synthase. 7 477 41.234 T 28-03-2018 IPR030874 Cardiolipin synthase, Firmicutes-type GO:0008808|GO:0032049 CIG75_RS16665 75a2722fb25fd7f19f14bc90b26b66b1 477 Pfam PF13091 PLD-like domain 133 274 9.0E-16 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CIG75_RS16665 75a2722fb25fd7f19f14bc90b26b66b1 477 Pfam PF13091 PLD-like domain 323 444 9.3E-24 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CIG75_RS16665 75a2722fb25fd7f19f14bc90b26b66b1 477 Gene3D G3DSA:3.30.870.10 85 280 7.0E-36 T 28-03-2018 CIG75_RS19850 b5fd3804606b3089d9809e7cbb9ea994 159 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 3 157 7.3E-70 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CIG75_RS19850 b5fd3804606b3089d9809e7cbb9ea994 159 Gene3D G3DSA:3.30.1330.50 1 159 1.3E-72 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CIG75_RS19850 b5fd3804606b3089d9809e7cbb9ea994 159 Pfam PF02542 YgbB family 2 155 2.5E-64 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CIG75_RS19850 b5fd3804606b3089d9809e7cbb9ea994 159 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 36 51 - T 28-03-2018 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CIG75_RS19850 b5fd3804606b3089d9809e7cbb9ea994 159 SUPERFAMILY SSF69765 1 157 7.72E-67 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CIG75_RS19850 b5fd3804606b3089d9809e7cbb9ea994 159 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 2 157 37.514 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CIG75_RS15270 2b196352b8bd93ad64daf83d1c32135a 212 Pfam PF10067 Predicted membrane protein (DUF2306) 59 201 5.6E-41 T 28-03-2018 IPR018750 Protein of unknown function DUF2306, membrane CIG75_RS11165 877b9cda2384289c5ac8db950037221f 695 Pfam PF07833 Copper amine oxidase N-terminal domain 599 689 8.2E-25 T 28-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CIG75_RS11165 877b9cda2384289c5ac8db950037221f 695 Gene3D G3DSA:3.30.457.10 670 693 2.7E-5 T 28-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CIG75_RS11165 877b9cda2384289c5ac8db950037221f 695 Gene3D G3DSA:3.30.457.10 504 608 0.12 T 28-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CIG75_RS11165 877b9cda2384289c5ac8db950037221f 695 Gene3D G3DSA:3.30.457.10 609 669 3.4E-23 T 28-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CIG75_RS11165 877b9cda2384289c5ac8db950037221f 695 SUPERFAMILY SSF55383 600 684 5.75E-22 T 28-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CIG75_RS08470 b6e437a03324bdeb8fb1405cceb65875 508 Pfam PF01039 Carboxyl transferase domain 22 506 3.8E-193 T 28-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 CIG75_RS08470 b6e437a03324bdeb8fb1405cceb65875 508 Gene3D G3DSA:3.90.226.10 249 500 1.6E-70 T 28-03-2018 CIG75_RS08470 b6e437a03324bdeb8fb1405cceb65875 508 Gene3D G3DSA:3.90.226.10 1 248 8.6E-79 T 28-03-2018 CIG75_RS08470 b6e437a03324bdeb8fb1405cceb65875 508 SUPERFAMILY SSF52096 261 508 2.05E-88 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CIG75_RS08470 b6e437a03324bdeb8fb1405cceb65875 508 SUPERFAMILY SSF52096 3 249 2.11E-79 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CIG75_RS15140 2f336c01d6bc88ab86c8d57afe04f6b5 403 SUPERFAMILY SSF48452 238 375 2.28E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS15140 2f336c01d6bc88ab86c8d57afe04f6b5 403 SMART SM00028 310 343 120.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS15140 2f336c01d6bc88ab86c8d57afe04f6b5 403 SMART SM00028 345 378 0.39 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS15140 2f336c01d6bc88ab86c8d57afe04f6b5 403 Gene3D G3DSA:1.25.40.10 58 268 4.2E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS15140 2f336c01d6bc88ab86c8d57afe04f6b5 403 Gene3D G3DSA:1.25.40.10 269 400 1.8E-16 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS20310 552d0ee39dfdf8376d815b763b60e6fb 271 Gene3D G3DSA:1.10.10.10 2 74 1.5E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS20310 552d0ee39dfdf8376d815b763b60e6fb 271 ProDom PD029816 REPRESSOR OPERON PUR TRANSCRIPTION PURINE TRANSCRIPTIONAL PURR REGULATION DNA-BINDING GLYCOSYLTRANSFERASE 10 74 2.0E-6 T 28-03-2018 IPR015265 Bacterial purine repressor, N-terminal GO:0003677|GO:0006355 CIG75_RS20310 552d0ee39dfdf8376d815b763b60e6fb 271 TIGRFAM TIGR01743 purR_Bsub: pur operon repressor PurR 4 268 7.7E-101 T 28-03-2018 IPR010078 Pur operon repressor GO:0003677|GO:0045892|GO:0045982 CIG75_RS20310 552d0ee39dfdf8376d815b763b60e6fb 271 Gene3D G3DSA:3.40.50.2020 77 266 1.5E-28 T 28-03-2018 CIG75_RS20310 552d0ee39dfdf8376d815b763b60e6fb 271 Pfam PF09182 Bacterial purine repressor, N-terminal 5 74 2.2E-28 T 28-03-2018 IPR015265 Bacterial purine repressor, N-terminal GO:0003677|GO:0006355 CIG75_RS20310 552d0ee39dfdf8376d815b763b60e6fb 271 SUPERFAMILY SSF53271 88 242 1.85E-33 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CIG75_RS20310 552d0ee39dfdf8376d815b763b60e6fb 271 Pfam PF00156 Phosphoribosyl transferase domain 118 263 1.3E-21 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CIG75_RS20310 552d0ee39dfdf8376d815b763b60e6fb 271 SUPERFAMILY SSF46785 3 74 2.79E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS15705 84e5760f01a52959d28854b6f86a01ba 130 Gene3D G3DSA:3.10.180.10 1 130 5.3E-29 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CIG75_RS15705 84e5760f01a52959d28854b6f86a01ba 130 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 124 1.3E-15 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CIG75_RS15705 84e5760f01a52959d28854b6f86a01ba 130 SUPERFAMILY SSF54593 3 127 1.88E-28 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CIG75_RS15705 84e5760f01a52959d28854b6f86a01ba 130 ProSitePatterns PS00934 Glyoxalase I signature 1. 8 29 - T 28-03-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 CIG75_RS17915 92d4441eae4e0415f4a9998ae56db558 121 Gene3D G3DSA:3.10.180.10 2 120 1.0E-17 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CIG75_RS17915 92d4441eae4e0415f4a9998ae56db558 121 SUPERFAMILY SSF54593 7 119 1.88E-19 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CIG75_RS17915 92d4441eae4e0415f4a9998ae56db558 121 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 117 3.4E-6 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CIG75_RS13035 f96ece1bef8fb76c515c95aac4af4d6a 428 Pfam PF01979 Amidohydrolase family 52 423 4.2E-40 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CIG75_RS13035 f96ece1bef8fb76c515c95aac4af4d6a 428 SUPERFAMILY SSF51338 1 54 4.63E-24 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CIG75_RS13035 f96ece1bef8fb76c515c95aac4af4d6a 428 SUPERFAMILY SSF51338 370 426 4.63E-24 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CIG75_RS13035 f96ece1bef8fb76c515c95aac4af4d6a 428 ProSitePatterns PS00483 Dihydroorotase signature 2. 306 317 - T 28-03-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CIG75_RS13035 f96ece1bef8fb76c515c95aac4af4d6a 428 Gene3D G3DSA:3.20.20.140 69 410 1.3E-109 T 28-03-2018 CIG75_RS13035 f96ece1bef8fb76c515c95aac4af4d6a 428 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 18 426 4.5E-135 T 28-03-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CIG75_RS13035 f96ece1bef8fb76c515c95aac4af4d6a 428 Gene3D G3DSA:2.30.40.10 1 68 3.5E-20 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CIG75_RS13035 f96ece1bef8fb76c515c95aac4af4d6a 428 SUPERFAMILY SSF51556 55 370 5.88E-111 T 28-03-2018 IPR032466 Metal-dependent hydrolase CIG75_RS13035 f96ece1bef8fb76c515c95aac4af4d6a 428 ProSitePatterns PS00482 Dihydroorotase signature 1. 58 66 - T 28-03-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CIG75_RS13035 f96ece1bef8fb76c515c95aac4af4d6a 428 Hamap MF_00220_B Dihydroorotase [pyrC]. 2 428 45.348 T 28-03-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CIG75_RS00725 82f3abe6c49a7dde84cdbf5404c04271 104 SUPERFAMILY SSF103481 6 102 1.1E-16 T 28-03-2018 CIG75_RS00725 82f3abe6c49a7dde84cdbf5404c04271 104 Pfam PF00893 Small Multidrug Resistance protein 1 93 8.0E-26 T 28-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 CIG75_RS02240 7a1b0f0b104f5486c6568e25b2605b95 606 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 170 332 3.1E-33 T 28-03-2018 IPR000160 GGDEF domain CIG75_RS02240 7a1b0f0b104f5486c6568e25b2605b95 606 Gene3D G3DSA:3.20.20.450 337 602 2.5E-108 T 28-03-2018 IPR001633 EAL domain CIG75_RS02240 7a1b0f0b104f5486c6568e25b2605b95 606 SMART SM00267 161 333 3.7E-55 T 28-03-2018 IPR000160 GGDEF domain CIG75_RS02240 7a1b0f0b104f5486c6568e25b2605b95 606 SUPERFAMILY SSF55073 177 334 6.51E-46 T 28-03-2018 IPR029787 Nucleotide cyclase CIG75_RS02240 7a1b0f0b104f5486c6568e25b2605b95 606 Pfam PF00990 Diguanylate cyclase, GGDEF domain 174 329 1.2E-41 T 28-03-2018 IPR000160 GGDEF domain CIG75_RS02240 7a1b0f0b104f5486c6568e25b2605b95 606 SMART SM00052 343 589 2.7E-134 T 28-03-2018 IPR001633 EAL domain CIG75_RS02240 7a1b0f0b104f5486c6568e25b2605b95 606 Gene3D G3DSA:3.30.70.270 165 336 7.9E-54 T 28-03-2018 CIG75_RS02240 7a1b0f0b104f5486c6568e25b2605b95 606 SUPERFAMILY SSF141868 349 596 8.63E-97 T 28-03-2018 IPR001633 EAL domain CIG75_RS02240 7a1b0f0b104f5486c6568e25b2605b95 606 Pfam PF00563 EAL domain 350 584 1.7E-74 T 28-03-2018 IPR001633 EAL domain CIG75_RS10445 e68e91f73c741cf9e323766ec7c52a8b 461 Gene3D G3DSA:3.20.20.140 69 404 9.0E-99 T 28-03-2018 CIG75_RS10445 e68e91f73c741cf9e323766ec7c52a8b 461 Pfam PF01979 Amidohydrolase family 49 435 2.9E-29 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CIG75_RS10445 e68e91f73c741cf9e323766ec7c52a8b 461 SUPERFAMILY SSF51338 350 459 1.38E-40 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CIG75_RS10445 e68e91f73c741cf9e323766ec7c52a8b 461 Gene3D G3DSA:2.30.40.10 3 68 8.1E-20 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CIG75_RS10445 e68e91f73c741cf9e323766ec7c52a8b 461 TIGRFAM TIGR02033 D-hydantoinase: dihydropyrimidinase 3 455 2.5E-208 T 28-03-2018 IPR011778 Hydantoinase/dihydropyrimidinase GO:0005737 Reactome: R-HSA-399956 CIG75_RS10445 e68e91f73c741cf9e323766ec7c52a8b 461 SUPERFAMILY SSF51338 2 67 1.06E-13 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CIG75_RS10445 e68e91f73c741cf9e323766ec7c52a8b 461 SUPERFAMILY SSF51556 53 383 1.26E-110 T 28-03-2018 IPR032466 Metal-dependent hydrolase CIG75_RS07065 0bd23897e1dea1de080f33d181347b27 191 Gene3D G3DSA:1.10.3210.10 1 185 9.2E-26 T 28-03-2018 CIG75_RS07065 0bd23897e1dea1de080f33d181347b27 191 TIGRFAM TIGR00488 TIGR00488: putative HD superfamily hydrolase 11 179 4.4E-43 T 28-03-2018 IPR005249 Conserved hypothetical protein CHP00488 CIG75_RS07065 0bd23897e1dea1de080f33d181347b27 191 SMART SM00471 14 140 0.0058 T 28-03-2018 IPR003607 HD/PDEase domain CIG75_RS07065 0bd23897e1dea1de080f33d181347b27 191 Pfam PF01966 HD domain 18 130 5.5E-11 T 28-03-2018 IPR006674 HD domain CIG75_RS07065 0bd23897e1dea1de080f33d181347b27 191 SUPERFAMILY SSF109604 5 182 1.6E-31 T 28-03-2018 CIG75_RS16400 45120cd44597f918f02d854ec153265d 365 SUPERFAMILY SSF48256 7 364 2.49E-117 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CIG75_RS16400 45120cd44597f918f02d854ec153265d 365 ProSitePatterns PS00480 Citrate synthase signature. 253 265 - T 28-03-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 CIG75_RS16400 45120cd44597f918f02d854ec153265d 365 Gene3D G3DSA:1.10.580.10 264 353 9.1E-6 T 28-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain CIG75_RS16400 45120cd44597f918f02d854ec153265d 365 PRINTS PR00143 Citrate synthase signature 193 221 2.0E-39 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CIG75_RS16400 45120cd44597f918f02d854ec153265d 365 PRINTS PR00143 Citrate synthase signature 246 266 2.0E-39 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CIG75_RS16400 45120cd44597f918f02d854ec153265d 365 PRINTS PR00143 Citrate synthase signature 122 135 2.0E-39 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CIG75_RS16400 45120cd44597f918f02d854ec153265d 365 PRINTS PR00143 Citrate synthase signature 307 323 2.0E-39 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CIG75_RS16400 45120cd44597f918f02d854ec153265d 365 PRINTS PR00143 Citrate synthase signature 171 186 2.0E-39 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CIG75_RS16400 45120cd44597f918f02d854ec153265d 365 PRINTS PR00143 Citrate synthase signature 327 341 2.0E-39 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CIG75_RS16400 45120cd44597f918f02d854ec153265d 365 PIRSF PIRSF001369 2 365 5.4E-121 T 28-03-2018 IPR024176 Citrate synthase, bacterial-type CIG75_RS16400 45120cd44597f918f02d854ec153265d 365 Pfam PF00285 Citrate synthase, C-terminal domain 8 356 3.3E-117 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CIG75_RS16400 45120cd44597f918f02d854ec153265d 365 Gene3D G3DSA:1.10.580.10 13 259 5.9E-85 T 28-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain CIG75_RS09960 40aa5fb07e5f8a92cfc75df0ca9905d7 226 Gene3D G3DSA:3.40.225.10 9 226 2.6E-59 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CIG75_RS09960 40aa5fb07e5f8a92cfc75df0ca9905d7 226 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 19 195 4.5E-49 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CIG75_RS09960 40aa5fb07e5f8a92cfc75df0ca9905d7 226 SUPERFAMILY SSF53639 16 218 1.79E-57 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CIG75_RS09960 40aa5fb07e5f8a92cfc75df0ca9905d7 226 SMART SM01007 18 196 6.9E-60 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CIG75_RS13940 24823c518eaf215b1845b516e4dd5572 129 Pfam PF06686 Stage III sporulation protein AC/AD protein family 3 57 1.5E-10 T 28-03-2018 IPR025664 Stage III sporulation protein AC/AD family CIG75_RS13940 24823c518eaf215b1845b516e4dd5572 129 Pfam PF06686 Stage III sporulation protein AC/AD protein family 71 125 3.3E-20 T 28-03-2018 IPR025664 Stage III sporulation protein AC/AD family CIG75_RS13940 24823c518eaf215b1845b516e4dd5572 129 TIGRFAM TIGR02849 spore_III_AD: stage III sporulation protein AD 28 127 3.8E-35 T 28-03-2018 IPR014211 Stage III sporulation protein AD CIG75_RS18160 3af0588c2abe2cadc8d4d263bc2eeef4 391 Pfam PF07690 Major Facilitator Superfamily 8 227 1.3E-21 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CIG75_RS18160 3af0588c2abe2cadc8d4d263bc2eeef4 391 SUPERFAMILY SSF103473 5 374 1.14E-47 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS18160 3af0588c2abe2cadc8d4d263bc2eeef4 391 Pfam PF00083 Sugar (and other) transporter 235 309 2.5E-5 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CIG75_RS18160 3af0588c2abe2cadc8d4d263bc2eeef4 391 Gene3D G3DSA:1.20.1250.20 192 381 1.2E-24 T 28-03-2018 CIG75_RS18160 3af0588c2abe2cadc8d4d263bc2eeef4 391 Gene3D G3DSA:1.20.1250.20 2 188 4.3E-24 T 28-03-2018 CIG75_RS17960 b111b062d77406b26f6f727e72590eb1 133 Pfam PF03061 Thioesterase superfamily 42 120 7.8E-14 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CIG75_RS17960 b111b062d77406b26f6f727e72590eb1 133 SUPERFAMILY SSF54637 10 131 7.11E-30 T 28-03-2018 IPR029069 HotDog domain CIG75_RS17960 b111b062d77406b26f6f727e72590eb1 133 Gene3D G3DSA:3.10.129.10 2 133 1.4E-26 T 28-03-2018 CIG75_RS17960 b111b062d77406b26f6f727e72590eb1 133 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 12 127 4.3E-36 T 28-03-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 CIG75_RS07935 8bb5e827fefa3583ff820969b22d5077 304 SUPERFAMILY SSF55120 80 301 8.02E-70 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CIG75_RS07935 8bb5e827fefa3583ff820969b22d5077 304 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 33 300 9.7E-77 T 28-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 CIG75_RS07935 8bb5e827fefa3583ff820969b22d5077 304 Gene3D G3DSA:3.30.2350.10 84 304 5.9E-69 T 28-03-2018 CIG75_RS07935 8bb5e827fefa3583ff820969b22d5077 304 Pfam PF00849 RNA pseudouridylate synthase 93 243 5.9E-30 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CIG75_RS06600 3b6ff95629193cb5473e13e2cef057b5 315 PIRSF PIRSF033887 6 310 2.4E-65 T 28-03-2018 IPR012363 Propanediol utilisation/coumermycin biosynthesis, PduX-related KEGG: 00040+2.7.1.17|KEGG: 00860+2.7.1.177|MetaCyc: PWY-5443 CIG75_RS06600 3b6ff95629193cb5473e13e2cef057b5 315 Gene3D G3DSA:3.30.230.10 46 207 1.5E-13 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CIG75_RS06600 3b6ff95629193cb5473e13e2cef057b5 315 Pfam PF00288 GHMP kinases N terminal domain 99 150 8.6E-10 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 CIG75_RS06600 3b6ff95629193cb5473e13e2cef057b5 315 SUPERFAMILY SSF54211 29 168 2.2E-15 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CIG75_RS10425 784220ad56ca9368565d5d364635fe18 429 Gene3D G3DSA:3.20.20.140 88 355 3.7E-41 T 28-03-2018 CIG75_RS10425 784220ad56ca9368565d5d364635fe18 429 Gene3D G3DSA:2.30.40.10 356 422 1.8E-14 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CIG75_RS10425 784220ad56ca9368565d5d364635fe18 429 Pfam PF01979 Amidohydrolase family 74 417 5.4E-24 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CIG75_RS10425 784220ad56ca9368565d5d364635fe18 429 Hamap MF_00372 Imidazolonepropionase [hutI]. 5 417 43.479 T 28-03-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CIG75_RS10425 784220ad56ca9368565d5d364635fe18 429 TIGRFAM TIGR01224 hutI: imidazolonepropionase 35 416 1.0E-148 T 28-03-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CIG75_RS10425 784220ad56ca9368565d5d364635fe18 429 SUPERFAMILY SSF51338 377 418 1.94E-19 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CIG75_RS10425 784220ad56ca9368565d5d364635fe18 429 SUPERFAMILY SSF51338 4 78 1.94E-19 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CIG75_RS10425 784220ad56ca9368565d5d364635fe18 429 Gene3D G3DSA:2.30.40.10 1 87 1.8E-18 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CIG75_RS10425 784220ad56ca9368565d5d364635fe18 429 SUPERFAMILY SSF51556 77 378 4.95E-81 T 28-03-2018 IPR032466 Metal-dependent hydrolase CIG75_RS00955 54ec6a86e973f7427df1cb4cd97f042d 550 Hamap MF_00126 Glutamine--tRNA ligase [glnS]. 1 547 49.594 T 28-03-2018 IPR022861 Glutamine-tRNA ligase, bacterial GO:0004819 KEGG: 00970+6.1.1.18 CIG75_RS00955 54ec6a86e973f7427df1cb4cd97f042d 550 Gene3D G3DSA:3.40.50.620 153 258 2.7E-19 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CIG75_RS00955 54ec6a86e973f7427df1cb4cd97f042d 550 Gene3D G3DSA:3.40.50.620 42 150 3.7E-35 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CIG75_RS00955 54ec6a86e973f7427df1cb4cd97f042d 550 Gene3D G3DSA:1.10.1160.10 259 335 1.3E-31 T 28-03-2018 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 CIG75_RS00955 54ec6a86e973f7427df1cb4cd97f042d 550 Pfam PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain 338 526 2.2E-58 T 28-03-2018 IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CIG75_RS00955 54ec6a86e973f7427df1cb4cd97f042d 550 SUPERFAMILY SSF50715 338 545 1.62E-70 T 28-03-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CIG75_RS00955 54ec6a86e973f7427df1cb4cd97f042d 550 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 26 334 5.1E-103 T 28-03-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 CIG75_RS00955 54ec6a86e973f7427df1cb4cd97f042d 550 PRINTS PR00987 Glutamyl-tRNA synthetase signature 30 42 1.3E-10 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CIG75_RS00955 54ec6a86e973f7427df1cb4cd97f042d 550 PRINTS PR00987 Glutamyl-tRNA synthetase signature 59 72 1.3E-10 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CIG75_RS00955 54ec6a86e973f7427df1cb4cd97f042d 550 PRINTS PR00987 Glutamyl-tRNA synthetase signature 208 218 1.3E-10 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CIG75_RS00955 54ec6a86e973f7427df1cb4cd97f042d 550 PRINTS PR00987 Glutamyl-tRNA synthetase signature 44 55 1.3E-10 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CIG75_RS00955 54ec6a86e973f7427df1cb4cd97f042d 550 Gene3D G3DSA:2.40.240.10 463 545 1.0E-29 T 28-03-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CIG75_RS00955 54ec6a86e973f7427df1cb4cd97f042d 550 Gene3D G3DSA:2.40.240.10 342 462 6.7E-51 T 28-03-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CIG75_RS00955 54ec6a86e973f7427df1cb4cd97f042d 550 Gene3D G3DSA:3.40.50.620 7 41 0.0096 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CIG75_RS00955 54ec6a86e973f7427df1cb4cd97f042d 550 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 33 44 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CIG75_RS00955 54ec6a86e973f7427df1cb4cd97f042d 550 SUPERFAMILY SSF52374 26 342 2.02E-91 T 28-03-2018 CIG75_RS00955 54ec6a86e973f7427df1cb4cd97f042d 550 TIGRFAM TIGR00440 glnS: glutamine--tRNA ligase 27 547 1.8E-219 T 28-03-2018 IPR004514 Glutamine-tRNA synthetase GO:0000166|GO:0004819|GO:0005524|GO:0005737|GO:0006425 KEGG: 00970+6.1.1.18|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CIG75_RS07645 45783e643110d22c01d59bca3ccc83b6 475 SUPERFAMILY SSF81442 20 466 7.98E-80 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CIG75_RS07645 45783e643110d22c01d59bca3ccc83b6 475 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 20 442 3.6E-74 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CIG75_RS07645 45783e643110d22c01d59bca3ccc83b6 475 Gene3D G3DSA:1.20.210.10 8 473 7.2E-61 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CIG75_RS15855 ce08763aa3e7b83a822b4f228056caff 412 Pfam PF07690 Major Facilitator Superfamily 19 238 1.5E-27 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CIG75_RS15855 ce08763aa3e7b83a822b4f228056caff 412 Gene3D G3DSA:1.20.1250.20 8 200 3.0E-29 T 28-03-2018 CIG75_RS15855 ce08763aa3e7b83a822b4f228056caff 412 Gene3D G3DSA:1.20.1250.20 201 400 1.1E-18 T 28-03-2018 CIG75_RS15855 ce08763aa3e7b83a822b4f228056caff 412 SUPERFAMILY SSF103473 9 394 3.4E-51 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS07070 55005429e32dc70b66518c9b1d044e68 115 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 5 107 25.905 T 28-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS CIG75_RS07070 55005429e32dc70b66518c9b1d044e68 115 Pfam PF02410 Ribosomal silencing factor during starvation 13 106 1.1E-28 T 28-03-2018 CIG75_RS07070 55005429e32dc70b66518c9b1d044e68 115 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 11 106 6.1E-37 T 28-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS CIG75_RS07070 55005429e32dc70b66518c9b1d044e68 115 Gene3D G3DSA:3.30.460.10 4 114 5.6E-34 T 28-03-2018 CIG75_RS07070 55005429e32dc70b66518c9b1d044e68 115 SUPERFAMILY SSF81301 6 112 2.62E-41 T 28-03-2018 CIG75_RS11975 2673e0016e7af6ae0701998963262d3d 262 TIGRFAM TIGR01400 fliR: flagellar biosynthetic protein FliR 10 252 1.5E-61 T 28-03-2018 IPR006303 Flagellar biosynthesis protein FliR GO:0016021|GO:0044780 CIG75_RS11975 2673e0016e7af6ae0701998963262d3d 262 Pfam PF01311 Bacterial export proteins, family 1 10 247 6.4E-67 T 28-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 CIG75_RS11975 2673e0016e7af6ae0701998963262d3d 262 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 18 39 7.2E-26 T 28-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 CIG75_RS11975 2673e0016e7af6ae0701998963262d3d 262 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 81 100 7.2E-26 T 28-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 CIG75_RS11975 2673e0016e7af6ae0701998963262d3d 262 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 181 203 7.2E-26 T 28-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 CIG75_RS11975 2673e0016e7af6ae0701998963262d3d 262 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 203 222 7.2E-26 T 28-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 CIG75_RS14575 ec5a0ff6d8327f27f11a045594548cca 780 Gene3D G3DSA:2.60.120.260 360 594 3.8E-24 T 28-03-2018 IPR008979 Galactose-binding domain-like CIG75_RS14575 ec5a0ff6d8327f27f11a045594548cca 780 PIRSF PIRSF007519 2 780 4.8E-279 T 28-03-2018 IPR012300 Peptidase M6, InhA CIG75_RS14575 ec5a0ff6d8327f27f11a045594548cca 780 SUPERFAMILY SSF55486 328 399 1.01E-15 T 28-03-2018 CIG75_RS14575 ec5a0ff6d8327f27f11a045594548cca 780 SUPERFAMILY SSF55486 233 279 1.01E-15 T 28-03-2018 CIG75_RS14575 ec5a0ff6d8327f27f11a045594548cca 780 Pfam PF05547 Immune inhibitor A peptidase M6 125 775 2.9E-252 T 28-03-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 CIG75_RS14575 ec5a0ff6d8327f27f11a045594548cca 780 TIGRFAM TIGR03296 M6dom_TIGR03296: M6 family metalloprotease domain 160 465 1.1E-79 T 28-03-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 CIG75_RS03405 af7f40e98496c4277539f1305a8b9ada 218 SMART SM00448 3 117 1.3E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CIG75_RS03405 af7f40e98496c4277539f1305a8b9ada 218 Pfam PF00072 Response regulator receiver domain 6 117 1.3E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CIG75_RS03405 af7f40e98496c4277539f1305a8b9ada 218 SMART SM00421 152 209 9.3E-26 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CIG75_RS03405 af7f40e98496c4277539f1305a8b9ada 218 Gene3D G3DSA:3.40.50.2300 2 128 9.8E-34 T 28-03-2018 CIG75_RS03405 af7f40e98496c4277539f1305a8b9ada 218 SUPERFAMILY SSF46894 149 216 1.33E-23 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CIG75_RS03405 af7f40e98496c4277539f1305a8b9ada 218 SUPERFAMILY SSF52172 1 132 2.28E-31 T 28-03-2018 IPR011006 CheY-like superfamily CIG75_RS03405 af7f40e98496c4277539f1305a8b9ada 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 3.4E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CIG75_RS03405 af7f40e98496c4277539f1305a8b9ada 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 3.4E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CIG75_RS03405 af7f40e98496c4277539f1305a8b9ada 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 3.4E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CIG75_RS03405 af7f40e98496c4277539f1305a8b9ada 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 209 1.6E-21 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CIG75_RS03405 af7f40e98496c4277539f1305a8b9ada 218 Gene3D G3DSA:1.10.10.10 129 218 8.5E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS05045 2b1b10064239bf6fdffddef8e4feb2fc 410 Gene3D G3DSA:1.20.1250.20 15 210 3.6E-16 T 28-03-2018 CIG75_RS05045 2b1b10064239bf6fdffddef8e4feb2fc 410 SUPERFAMILY SSF103473 17 407 5.75E-43 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS05045 2b1b10064239bf6fdffddef8e4feb2fc 410 Pfam PF05977 Transmembrane secretion effector 19 408 2.0E-26 T 28-03-2018 IPR010290 Transmembrane secretion effector CIG75_RS05045 2b1b10064239bf6fdffddef8e4feb2fc 410 Gene3D G3DSA:1.20.1250.20 211 409 5.8E-14 T 28-03-2018 CIG75_RS02405 364b242283bb22bf28743a22729aa7ba 134 TIGRFAM TIGR00208 fliS: flagellar protein FliS 2 119 9.5E-31 T 28-03-2018 IPR003713 Flagellar protein FliS GO:0044780 CIG75_RS02405 364b242283bb22bf28743a22729aa7ba 134 Gene3D G3DSA:1.20.120.340 1 122 5.1E-39 T 28-03-2018 CIG75_RS02405 364b242283bb22bf28743a22729aa7ba 134 Pfam PF02561 Flagellar protein FliS 6 119 1.4E-37 T 28-03-2018 IPR003713 Flagellar protein FliS GO:0044780 CIG75_RS02405 364b242283bb22bf28743a22729aa7ba 134 SUPERFAMILY SSF101116 3 123 4.45E-36 T 28-03-2018 IPR003713 Flagellar protein FliS GO:0044780 CIG75_RS02405 364b242283bb22bf28743a22729aa7ba 134 PIRSF PIRSF039090 1 128 1.5E-34 T 28-03-2018 IPR003713 Flagellar protein FliS GO:0044780 CIG75_RS14240 1ee008db101c8e03ddb7e7657c3ea1e0 497 SUPERFAMILY SSF100950 4 224 3.26E-70 T 28-03-2018 CIG75_RS14240 1ee008db101c8e03ddb7e7657c3ea1e0 497 Gene3D G3DSA:3.40.1080.10 13 237 3.3E-32 T 28-03-2018 CIG75_RS14240 1ee008db101c8e03ddb7e7657c3ea1e0 497 TIGRFAM TIGR03458 YgfH_subfam: succinate CoA transferase 13 496 9.1E-235 T 28-03-2018 IPR017821 Succinate CoA transferase GO:0006084|GO:0016740 CIG75_RS14240 1ee008db101c8e03ddb7e7657c3ea1e0 497 Pfam PF13336 Acetyl-CoA hydrolase/transferase C-terminal domain 326 465 2.5E-42 T 28-03-2018 IPR026888 Acetyl-CoA hydrolase/transferase C-terminal domain CIG75_RS14240 1ee008db101c8e03ddb7e7657c3ea1e0 497 Pfam PF02550 Acetyl-CoA hydrolase/transferase N-terminal domain 9 217 3.7E-28 T 28-03-2018 IPR003702 Acetyl-CoA hydrolase/transferase GO:0003824|GO:0006084 CIG75_RS14240 1ee008db101c8e03ddb7e7657c3ea1e0 497 Gene3D G3DSA:3.40.1080.10 238 497 3.3E-56 T 28-03-2018 CIG75_RS14240 1ee008db101c8e03ddb7e7657c3ea1e0 497 SUPERFAMILY SSF100950 229 496 4.35E-82 T 28-03-2018 CIG75_RS08890 f45b1196de1be08429469306f94a5449 67 Pfam PF02597 ThiS family 4 66 6.5E-14 T 28-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 CIG75_RS08890 f45b1196de1be08429469306f94a5449 67 SUPERFAMILY SSF54285 3 65 1.12E-17 T 28-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp CIG75_RS08890 f45b1196de1be08429469306f94a5449 67 Gene3D G3DSA:3.10.20.30 1 66 2.9E-21 T 28-03-2018 IPR012675 Beta-grasp domain CIG75_RS08890 f45b1196de1be08429469306f94a5449 67 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 4 66 4.3E-22 T 28-03-2018 IPR010035 ThiS, thiamine-biosynthesis CIG75_RS09490 ee11a8eac23454908333e2b3b8acd24f 570 Gene3D G3DSA:3.40.50.150 16 297 1.4E-30 T 28-03-2018 CIG75_RS09490 ee11a8eac23454908333e2b3b8acd24f 570 SUPERFAMILY SSF53335 16 296 1.22E-40 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CIG75_RS09490 ee11a8eac23454908333e2b3b8acd24f 570 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 22 38 1.1E-17 T 28-03-2018 CIG75_RS09490 ee11a8eac23454908333e2b3b8acd24f 570 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 152 164 1.1E-17 T 28-03-2018 CIG75_RS09490 ee11a8eac23454908333e2b3b8acd24f 570 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 51 65 1.1E-17 T 28-03-2018 CIG75_RS09490 ee11a8eac23454908333e2b3b8acd24f 570 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 187 211 1.1E-17 T 28-03-2018 CIG75_RS09490 ee11a8eac23454908333e2b3b8acd24f 570 Gene3D G3DSA:3.90.220.10 318 530 3.2E-29 T 28-03-2018 CIG75_RS09490 ee11a8eac23454908333e2b3b8acd24f 570 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 155 161 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CIG75_RS09490 ee11a8eac23454908333e2b3b8acd24f 570 Pfam PF12950 TaqI-like C-terminal specificity domain 401 521 7.0E-11 T 28-03-2018 IPR025931 TaqI-like C-terminal specificity domain CIG75_RS09490 ee11a8eac23454908333e2b3b8acd24f 570 Pfam PF02384 N-6 DNA Methylase 16 289 3.2E-14 T 28-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 CIG75_RS08965 25a7cb197645c84cdb5d0967f913637e 313 Gene3D G3DSA:3.40.630.30 138 313 2.0E-19 T 28-03-2018 CIG75_RS08965 25a7cb197645c84cdb5d0967f913637e 313 SUPERFAMILY SSF55729 83 308 3.38E-20 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CIG75_RS08965 25a7cb197645c84cdb5d0967f913637e 313 Gene3D G3DSA:3.40.630.30 2 136 2.3E-5 T 28-03-2018 CIG75_RS08965 25a7cb197645c84cdb5d0967f913637e 313 Pfam PF00583 Acetyltransferase (GNAT) family 191 299 1.5E-8 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CIG75_RS10980 77f0b5cbb47639e202706e75a19758d5 329 Pfam PF14028 Lantibiotic biosynthesis dehydratase C-term 9 318 1.6E-62 T 28-03-2018 IPR023809 Thiopeptide-type bacteriocin biosynthesis domain CIG75_RS10980 77f0b5cbb47639e202706e75a19758d5 329 TIGRFAM TIGR03891 thiopep_ocin: thiopeptide-type bacteriocin biosynthesis domain 9 74 2.0E-14 T 28-03-2018 IPR023809 Thiopeptide-type bacteriocin biosynthesis domain CIG75_RS09095 5d06902a9e788cf43f4f34556b0e13e5 311 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 9 292 7.9E-67 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CIG75_RS09095 5d06902a9e788cf43f4f34556b0e13e5 311 Gene3D G3DSA:3.40.50.1100 42 139 8.4E-39 T 28-03-2018 CIG75_RS09095 5d06902a9e788cf43f4f34556b0e13e5 311 Gene3D G3DSA:3.40.50.1100 140 307 9.5E-54 T 28-03-2018 CIG75_RS09095 5d06902a9e788cf43f4f34556b0e13e5 311 TIGRFAM TIGR01139 cysK: cysteine synthase A 8 304 1.6E-130 T 28-03-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 CIG75_RS09095 5d06902a9e788cf43f4f34556b0e13e5 311 SUPERFAMILY SSF53686 1 304 6.42E-97 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CIG75_RS09095 5d06902a9e788cf43f4f34556b0e13e5 311 TIGRFAM TIGR01136 cysKM: cysteine synthase 8 304 1.8E-124 T 28-03-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 CIG75_RS09095 5d06902a9e788cf43f4f34556b0e13e5 311 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 28-03-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 CIG75_RS06265 b17cc655a92a59b36991b7f353fb3d28 275 Pfam PF03180 NLPA lipoprotein 40 275 2.3E-97 T 28-03-2018 IPR004872 Lipoprotein NlpA family CIG75_RS06265 b17cc655a92a59b36991b7f353fb3d28 275 SUPERFAMILY SSF53850 39 275 5.6E-84 T 28-03-2018 CIG75_RS06265 b17cc655a92a59b36991b7f353fb3d28 275 Gene3D G3DSA:3.40.190.10 39 154 1.1E-41 T 28-03-2018 CIG75_RS06265 b17cc655a92a59b36991b7f353fb3d28 275 Gene3D G3DSA:3.40.190.10 155 275 1.0E-46 T 28-03-2018 CIG75_RS06265 b17cc655a92a59b36991b7f353fb3d28 275 PIRSF PIRSF002854 1 275 9.0E-107 T 28-03-2018 IPR004872 Lipoprotein NlpA family CIG75_RS16860 7b62b75553a72a7e582fe8b54bfcdcc6 274 SMART SM00382 28 249 5.0E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS16860 7b62b75553a72a7e582fe8b54bfcdcc6 274 Pfam PF00005 ABC transporter 20 167 4.4E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS16860 7b62b75553a72a7e582fe8b54bfcdcc6 274 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS16860 7b62b75553a72a7e582fe8b54bfcdcc6 274 SUPERFAMILY SSF52540 4 230 2.13E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS16860 7b62b75553a72a7e582fe8b54bfcdcc6 274 Gene3D G3DSA:3.40.50.300 1 240 8.8E-60 T 28-03-2018 CIG75_RS15260 18bededca14736020a5d0fab78f9d8c4 159 Pfam PF02681 Divergent PAP2 family 5 149 4.0E-48 T 28-03-2018 IPR003832 Acid phosphatase/vanadium-dependent haloperoxidase-related CIG75_RS15260 18bededca14736020a5d0fab78f9d8c4 159 Gene3D G3DSA:1.20.144.10 5 158 5.1E-8 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CIG75_RS01300 dd6388a6bd1dff325d6af3412e3ab803 438 Pfam PF00860 Permease family 6 384 2.7E-116 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CIG75_RS01300 dd6388a6bd1dff325d6af3412e3ab803 438 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 5 413 1.1E-132 T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CIG75_RS01300 dd6388a6bd1dff325d6af3412e3ab803 438 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 331 351 - T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CIG75_RS01300 dd6388a6bd1dff325d6af3412e3ab803 438 TIGRFAM TIGR03173 pbuX: xanthine permease 10 416 2.0E-167 T 28-03-2018 IPR017588 Uric acid permease UacT-like GO:0006810|GO:0016021 CIG75_RS16960 d35a5470ed65eb2360cbaba337804ab5 187 PIRSF PIRSF015617 1 187 1.4E-60 T 28-03-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 CIG75_RS16960 d35a5470ed65eb2360cbaba337804ab5 187 SUPERFAMILY SSF52540 9 187 2.11E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS16960 d35a5470ed65eb2360cbaba337804ab5 187 Gene3D G3DSA:3.40.50.300 1 187 6.9E-66 T 28-03-2018 CIG75_RS16960 d35a5470ed65eb2360cbaba337804ab5 187 TIGRFAM TIGR00708 cobA: cob(I)yrinic acid a,c-diamide adenosyltransferase 11 187 4.4E-52 T 28-03-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 CIG75_RS16960 d35a5470ed65eb2360cbaba337804ab5 187 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 13 187 9.5E-59 T 28-03-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 CIG75_RS07955 dee454ae02b56c18a12d19a208a36673 342 Gene3D G3DSA:3.30.200.20 18 103 4.9E-14 T 28-03-2018 CIG75_RS07955 dee454ae02b56c18a12d19a208a36673 342 TIGRFAM TIGR02906 spore_CotS: spore coat protein, CotS family 27 337 4.3E-77 T 28-03-2018 IPR014255 Spore coat protein CotS CIG75_RS07955 dee454ae02b56c18a12d19a208a36673 342 Pfam PF01636 Phosphotransferase enzyme family 36 263 9.5E-17 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CIG75_RS07955 dee454ae02b56c18a12d19a208a36673 342 Gene3D G3DSA:3.90.1200.10 104 338 2.0E-30 T 28-03-2018 CIG75_RS07955 dee454ae02b56c18a12d19a208a36673 342 SUPERFAMILY SSF56112 22 323 1.47E-44 T 28-03-2018 IPR011009 Protein kinase-like domain CIG75_RS15325 6feafbe68815a1ac9b1d88808460f55f 281 SUPERFAMILY SSF56784 148 276 2.16E-23 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS15325 6feafbe68815a1ac9b1d88808460f55f 281 SUPERFAMILY SSF56784 1 106 2.16E-23 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS15325 6feafbe68815a1ac9b1d88808460f55f 281 Gene3D G3DSA:3.40.50.1000 1 59 0.17 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS15325 6feafbe68815a1ac9b1d88808460f55f 281 Gene3D G3DSA:3.40.50.1000 134 280 4.5E-18 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS15325 6feafbe68815a1ac9b1d88808460f55f 281 Pfam PF13419 Haloacid dehalogenase-like hydrolase 9 248 2.7E-5 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS12440 39680bf44203c894017864b20a3663ee 685 Pfam PF00271 Helicase conserved C-terminal domain 464 575 2.9E-17 T 28-03-2018 IPR001650 Helicase, C-terminal CIG75_RS12440 39680bf44203c894017864b20a3663ee 685 SUPERFAMILY SSF52540 176 439 2.46E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS12440 39680bf44203c894017864b20a3663ee 685 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 25 650 3.4E-229 T 28-03-2018 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 CIG75_RS12440 39680bf44203c894017864b20a3663ee 685 Pfam PF00270 DEAD/DEAH box helicase 264 420 4.2E-17 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CIG75_RS12440 39680bf44203c894017864b20a3663ee 685 SMART SM00487 256 446 3.5E-33 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CIG75_RS12440 39680bf44203c894017864b20a3663ee 685 Pfam PF17191 RecG wedge domain 11 168 4.3E-18 T 28-03-2018 IPR033454 RecG, wedge domain CIG75_RS12440 39680bf44203c894017864b20a3663ee 685 Gene3D G3DSA:3.40.50.300 444 616 1.5E-31 T 28-03-2018 CIG75_RS12440 39680bf44203c894017864b20a3663ee 685 SMART SM00490 492 576 3.7E-21 T 28-03-2018 IPR001650 Helicase, C-terminal CIG75_RS12440 39680bf44203c894017864b20a3663ee 685 SUPERFAMILY SSF50249 6 170 5.82E-32 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CIG75_RS12440 39680bf44203c894017864b20a3663ee 685 Gene3D G3DSA:2.40.50.140 44 141 2.1E-7 T 28-03-2018 CIG75_RS12440 39680bf44203c894017864b20a3663ee 685 Gene3D G3DSA:3.40.50.300 241 443 4.4E-36 T 28-03-2018 CIG75_RS12440 39680bf44203c894017864b20a3663ee 685 SUPERFAMILY SSF52540 439 641 2.21E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS01330 fcaed901b794e550f22816dba51a2654 186 SUPERFAMILY SSF81330 45 164 1.31E-34 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CIG75_RS01330 fcaed901b794e550f22816dba51a2654 186 ProSitePatterns PS01327 Large-conductance mechanosensitive channels mscL family signature. 45 58 - T 28-03-2018 IPR019823 Large-conductance mechanosensitive channel, conserved site CIG75_RS01330 fcaed901b794e550f22816dba51a2654 186 Hamap MF_00115 Large-conductance mechanosensitive channel [mscL]. 35 171 26.03 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CIG75_RS01330 fcaed901b794e550f22816dba51a2654 186 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 36 148 1.7E-38 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CIG75_RS01330 fcaed901b794e550f22816dba51a2654 186 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 36 164 5.6E-40 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CIG75_RS01330 fcaed901b794e550f22816dba51a2654 186 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 132 141 2.4E-12 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CIG75_RS01330 fcaed901b794e550f22816dba51a2654 186 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 38 52 2.4E-12 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CIG75_RS01330 fcaed901b794e550f22816dba51a2654 186 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 123 131 2.4E-12 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CIG75_RS14725 3fd15fdae0b0dc541a4f524bcd1f798c 167 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 5 166 24.078 T 28-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 CIG75_RS14725 3fd15fdae0b0dc541a4f524bcd1f798c 167 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 43 161 2.4E-40 T 28-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 CIG75_RS14725 3fd15fdae0b0dc541a4f524bcd1f798c 167 SUPERFAMILY SSF55486 20 166 9.03E-43 T 28-03-2018 CIG75_RS14725 3fd15fdae0b0dc541a4f524bcd1f798c 167 Pfam PF02130 Uncharacterized protein family UPF0054 19 159 5.4E-46 T 28-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 CIG75_RS14725 3fd15fdae0b0dc541a4f524bcd1f798c 167 Gene3D G3DSA:3.40.390.30 1 167 2.3E-50 T 28-03-2018 IPR023091 Metalloprotease catalytic domain, predicted GO:0004222 CIG75_RS14725 3fd15fdae0b0dc541a4f524bcd1f798c 167 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 132 142 - T 28-03-2018 IPR020549 Endoribonuclease YbeY, conserved site CIG75_RS12485 5e3b421bc70e433b2577ef386d09d922 658 SMART SM00220 10 270 6.2E-70 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CIG75_RS12485 5e3b421bc70e433b2577ef386d09d922 658 Gene3D G3DSA:1.10.510.10 109 274 2.4E-46 T 28-03-2018 CIG75_RS12485 5e3b421bc70e433b2577ef386d09d922 658 Pfam PF00069 Protein kinase domain 10 257 9.3E-55 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CIG75_RS12485 5e3b421bc70e433b2577ef386d09d922 658 Gene3D G3DSA:1.10.720.40 362 499 0.14 T 28-03-2018 IPR011015 LEM/LEM-like domain CIG75_RS12485 5e3b421bc70e433b2577ef386d09d922 658 PIRSF PIRSF000615 86 214 3.2E-13 T 28-03-2018 CIG75_RS12485 5e3b421bc70e433b2577ef386d09d922 658 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 129 141 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CIG75_RS12485 5e3b421bc70e433b2577ef386d09d922 658 SUPERFAMILY SSF56112 6 273 5.26E-84 T 28-03-2018 IPR011009 Protein kinase-like domain CIG75_RS12485 5e3b421bc70e433b2577ef386d09d922 658 Gene3D G3DSA:3.30.200.20 2 108 2.5E-28 T 28-03-2018 CIG75_RS12485 5e3b421bc70e433b2577ef386d09d922 658 Pfam PF03793 PASTA domain 441 506 3.5E-11 T 28-03-2018 IPR005543 PASTA domain CIG75_RS12485 5e3b421bc70e433b2577ef386d09d922 658 Pfam PF03793 PASTA domain 371 436 1.4E-18 T 28-03-2018 IPR005543 PASTA domain CIG75_RS12485 5e3b421bc70e433b2577ef386d09d922 658 Pfam PF03793 PASTA domain 512 576 1.6E-15 T 28-03-2018 IPR005543 PASTA domain CIG75_RS12485 5e3b421bc70e433b2577ef386d09d922 658 SMART SM00740 507 576 3.5E-14 T 28-03-2018 IPR005543 PASTA domain CIG75_RS12485 5e3b421bc70e433b2577ef386d09d922 658 SMART SM00740 437 506 5.0E-14 T 28-03-2018 IPR005543 PASTA domain CIG75_RS12485 5e3b421bc70e433b2577ef386d09d922 658 SMART SM00740 367 436 5.9E-18 T 28-03-2018 IPR005543 PASTA domain CIG75_RS06560 924ca915c8466c2f770e437a596c2f8a 492 SUPERFAMILY SSF52777 239 479 1.11E-54 T 28-03-2018 CIG75_RS06560 924ca915c8466c2f770e437a596c2f8a 492 SUPERFAMILY SSF52777 51 228 1.45E-38 T 28-03-2018 CIG75_RS06560 924ca915c8466c2f770e437a596c2f8a 492 Gene3D G3DSA:3.30.559.10 21 251 1.9E-31 T 28-03-2018 CIG75_RS06560 924ca915c8466c2f770e437a596c2f8a 492 Pfam PF00668 Condensation domain 50 483 1.1E-87 T 28-03-2018 IPR001242 Condensation domain CIG75_RS01755 cca7391799898a49dca8f88a720df330 234 SMART SM00248 111 140 3.4E-4 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 CIG75_RS01755 cca7391799898a49dca8f88a720df330 234 SMART SM00248 19 48 3800.0 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 CIG75_RS01755 cca7391799898a49dca8f88a720df330 234 SMART SM00248 146 175 0.28 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 CIG75_RS01755 cca7391799898a49dca8f88a720df330 234 SMART SM00248 179 208 4.6E-7 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 CIG75_RS01755 cca7391799898a49dca8f88a720df330 234 SMART SM00248 53 82 2.7 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 CIG75_RS01755 cca7391799898a49dca8f88a720df330 234 Pfam PF12796 Ankyrin repeats (3 copies) 85 140 5.3E-7 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain CIG75_RS01755 cca7391799898a49dca8f88a720df330 234 SUPERFAMILY SSF48403 22 232 1.11E-44 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain CIG75_RS01755 cca7391799898a49dca8f88a720df330 234 Gene3D G3DSA:1.25.40.20 81 234 6.0E-41 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain CIG75_RS01755 cca7391799898a49dca8f88a720df330 234 Pfam PF13857 Ankyrin repeats (many copies) 166 220 1.4E-13 T 28-03-2018 CIG75_RS01755 cca7391799898a49dca8f88a720df330 234 PRINTS PR01415 Ankyrin repeat signature 195 209 1.9E-6 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 CIG75_RS01755 cca7391799898a49dca8f88a720df330 234 PRINTS PR01415 Ankyrin repeat signature 112 127 1.9E-6 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 CIG75_RS01755 cca7391799898a49dca8f88a720df330 234 Gene3D G3DSA:1.25.40.20 18 80 5.6E-10 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain CIG75_RS10930 d737ca0c02fe869a218c39dc7138c5d3 341 PIRSF PIRSF001123 1 341 1.0E-109 T 28-03-2018 IPR008007 Peptidase M42 CIG75_RS10930 d737ca0c02fe869a218c39dc7138c5d3 341 SUPERFAMILY SSF53187 162 334 4.04E-61 T 28-03-2018 CIG75_RS10930 d737ca0c02fe869a218c39dc7138c5d3 341 SUPERFAMILY SSF53187 2 75 4.04E-61 T 28-03-2018 CIG75_RS10930 d737ca0c02fe869a218c39dc7138c5d3 341 Gene3D G3DSA:2.40.30.40 64 143 2.5E-21 T 28-03-2018 IPR023367 Peptidase M42, domain 2 CIG75_RS10930 d737ca0c02fe869a218c39dc7138c5d3 341 Pfam PF05343 M42 glutamyl aminopeptidase 40 326 5.0E-87 T 28-03-2018 IPR008007 Peptidase M42 CIG75_RS10930 d737ca0c02fe869a218c39dc7138c5d3 341 SUPERFAMILY SSF101821 67 170 4.88E-20 T 28-03-2018 CIG75_RS10930 d737ca0c02fe869a218c39dc7138c5d3 341 Gene3D G3DSA:3.40.630.10 144 338 1.5E-38 T 28-03-2018 CIG75_RS09435 28ee83d7a5f31db4288514152822ae41 538 Gene3D G3DSA:3.40.50.980 193 344 3.4E-34 T 28-03-2018 CIG75_RS09435 28ee83d7a5f31db4288514152822ae41 538 Gene3D G3DSA:3.30.300.30 432 538 1.1E-28 T 28-03-2018 CIG75_RS09435 28ee83d7a5f31db4288514152822ae41 538 Gene3D G3DSA:3.40.50.980 55 192 4.8E-37 T 28-03-2018 CIG75_RS09435 28ee83d7a5f31db4288514152822ae41 538 Gene3D G3DSA:2.30.38.10 345 429 3.4E-22 T 28-03-2018 CIG75_RS09435 28ee83d7a5f31db4288514152822ae41 538 Pfam PF00501 AMP-binding enzyme 33 436 3.9E-79 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS09435 28ee83d7a5f31db4288514152822ae41 538 Pfam PF13193 AMP-binding enzyme C-terminal domain 445 523 5.8E-21 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS09435 28ee83d7a5f31db4288514152822ae41 538 ProSitePatterns PS00455 Putative AMP-binding domain signature. 188 199 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS09435 28ee83d7a5f31db4288514152822ae41 538 SUPERFAMILY SSF56801 17 535 2.49E-146 T 28-03-2018 CIG75_RS11835 59ac08f8b234990052af8a82b3a00a6d 572 SUPERFAMILY SSF52954 465 568 6.64E-31 T 28-03-2018 IPR004154 Anticodon-binding CIG75_RS11835 59ac08f8b234990052af8a82b3a00a6d 572 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 1 563 1.4E-222 T 28-03-2018 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 CIG75_RS11835 59ac08f8b234990052af8a82b3a00a6d 572 Pfam PF04073 Aminoacyl-tRNA editing domain 261 378 2.1E-27 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CIG75_RS11835 59ac08f8b234990052af8a82b3a00a6d 572 PIRSF PIRSF001535 1 571 1.2E-259 T 28-03-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 CIG75_RS11835 59ac08f8b234990052af8a82b3a00a6d 572 SUPERFAMILY SSF55681 9 238 1.38E-96 T 28-03-2018 CIG75_RS11835 59ac08f8b234990052af8a82b3a00a6d 572 SUPERFAMILY SSF55681 408 479 1.38E-96 T 28-03-2018 CIG75_RS11835 59ac08f8b234990052af8a82b3a00a6d 572 Gene3D G3DSA:3.30.930.10 1 260 1.6E-69 T 28-03-2018 CIG75_RS11835 59ac08f8b234990052af8a82b3a00a6d 572 Gene3D G3DSA:3.30.930.10 380 463 2.1E-19 T 28-03-2018 CIG75_RS11835 59ac08f8b234990052af8a82b3a00a6d 572 SUPERFAMILY SSF55826 219 390 2.35E-33 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CIG75_RS11835 59ac08f8b234990052af8a82b3a00a6d 572 PRINTS PR01046 Prolyl-tRNA synthetase signature 134 142 4.0E-17 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CIG75_RS11835 59ac08f8b234990052af8a82b3a00a6d 572 PRINTS PR01046 Prolyl-tRNA synthetase signature 68 86 4.0E-17 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CIG75_RS11835 59ac08f8b234990052af8a82b3a00a6d 572 PRINTS PR01046 Prolyl-tRNA synthetase signature 144 155 4.0E-17 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CIG75_RS11835 59ac08f8b234990052af8a82b3a00a6d 572 PRINTS PR01046 Prolyl-tRNA synthetase signature 104 115 4.0E-17 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CIG75_RS11835 59ac08f8b234990052af8a82b3a00a6d 572 Gene3D G3DSA:3.40.50.800 464 570 7.3E-31 T 28-03-2018 IPR004154 Anticodon-binding CIG75_RS11835 59ac08f8b234990052af8a82b3a00a6d 572 Pfam PF03129 Anticodon binding domain 476 565 1.9E-21 T 28-03-2018 IPR004154 Anticodon-binding CIG75_RS11835 59ac08f8b234990052af8a82b3a00a6d 572 Hamap MF_01569 Proline--tRNA ligase [proS]. 1 570 41.304 T 28-03-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 CIG75_RS11835 59ac08f8b234990052af8a82b3a00a6d 572 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 95 460 2.2E-47 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CIG75_RS11835 59ac08f8b234990052af8a82b3a00a6d 572 Gene3D G3DSA:3.90.960.10 261 379 3.4E-42 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CIG75_RS12040 38c34eb45777717577b249c9a1d1461a 185 SUPERFAMILY SSF90250 75 133 4.19E-5 T 28-03-2018 CIG75_RS12040 38c34eb45777717577b249c9a1d1461a 185 Gene3D G3DSA:1.10.220.30 130 185 6.8E-7 T 28-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical CIG75_RS12040 38c34eb45777717577b249c9a1d1461a 185 Gene3D G3DSA:1.20.5.170 85 116 5.6E-4 T 28-03-2018 CIG75_RS12040 38c34eb45777717577b249c9a1d1461a 185 Gene3D G3DSA:1.20.5.50 69 84 0.26 T 28-03-2018 CIG75_RS12040 38c34eb45777717577b249c9a1d1461a 185 Pfam PF03448 MgtE intracellular N domain 131 184 2.3E-6 T 28-03-2018 IPR006668 Magnesium transporter, MgtE intracellular domain CIG75_RS12040 38c34eb45777717577b249c9a1d1461a 185 SUPERFAMILY SSF158791 131 183 9.55E-7 T 28-03-2018 CIG75_RS19770 0b308e22a5359f07dbab1ec4c0f6c287 1177 Gene3D G3DSA:2.40.50.100 671 749 2.1E-26 T 28-03-2018 CIG75_RS19770 0b308e22a5359f07dbab1ec4c0f6c287 1177 Pfam PF04561 RNA polymerase Rpb2, domain 2 139 283 8.7E-29 T 28-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CIG75_RS19770 0b308e22a5359f07dbab1ec4c0f6c287 1177 Pfam PF04561 RNA polymerase Rpb2, domain 2 367 408 3.2E-8 T 28-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CIG75_RS19770 0b308e22a5359f07dbab1ec4c0f6c287 1177 Pfam PF04560 RNA polymerase Rpb2, domain 7 1069 1143 2.2E-27 T 28-03-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CIG75_RS19770 0b308e22a5359f07dbab1ec4c0f6c287 1177 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 14 1145 12.707 T 28-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CIG75_RS19770 0b308e22a5359f07dbab1ec4c0f6c287 1177 Pfam PF00562 RNA polymerase Rpb2, domain 6 673 1067 7.6E-166 T 28-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CIG75_RS19770 0b308e22a5359f07dbab1ec4c0f6c287 1177 Gene3D G3DSA:2.40.270.10 750 843 1.5E-12 T 28-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CIG75_RS19770 0b308e22a5359f07dbab1ec4c0f6c287 1177 Pfam PF04563 RNA polymerase beta subunit 27 452 4.1E-30 T 28-03-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CIG75_RS19770 0b308e22a5359f07dbab1ec4c0f6c287 1177 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 203 894 0.0 T 28-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CIG75_RS19770 0b308e22a5359f07dbab1ec4c0f6c287 1177 Gene3D G3DSA:3.90.1800.10 1070 1114 8.0E-12 T 28-03-2018 CIG75_RS19770 0b308e22a5359f07dbab1ec4c0f6c287 1177 SUPERFAMILY SSF64484 365 1154 0.0 T 28-03-2018 CIG75_RS19770 0b308e22a5359f07dbab1ec4c0f6c287 1177 SUPERFAMILY SSF64484 12 285 0.0 T 28-03-2018 CIG75_RS19770 0b308e22a5359f07dbab1ec4c0f6c287 1177 Pfam PF04565 RNA polymerase Rpb2, domain 3 467 535 7.8E-31 T 28-03-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CIG75_RS19770 0b308e22a5359f07dbab1ec4c0f6c287 1177 ProSitePatterns PS01166 RNA polymerases beta chain signature. 920 932 - T 28-03-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CIG75_RS19770 0b308e22a5359f07dbab1ec4c0f6c287 1177 Pfam PF10385 RNA polymerase beta subunit external 1 domain 545 612 6.4E-26 T 28-03-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CIG75_RS19770 0b308e22a5359f07dbab1ec4c0f6c287 1177 Gene3D G3DSA:2.40.270.10 844 1053 2.6E-79 T 28-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CIG75_RS19770 0b308e22a5359f07dbab1ec4c0f6c287 1177 Gene3D G3DSA:3.90.1100.10 601 669 1.7E-13 T 28-03-2018 CIG75_RS19770 0b308e22a5359f07dbab1ec4c0f6c287 1177 Gene3D G3DSA:3.90.1100.10 19 241 5.2E-57 T 28-03-2018 CIG75_RS19770 0b308e22a5359f07dbab1ec4c0f6c287 1177 Gene3D G3DSA:3.90.1100.10 323 600 5.4E-85 T 28-03-2018 CIG75_RS01825 5384342a2524255ba37ce150ba1ea4aa 166 Gene3D G3DSA:3.40.630.30 3 150 1.1E-5 T 28-03-2018 CIG75_RS01825 5384342a2524255ba37ce150ba1ea4aa 166 SUPERFAMILY SSF55729 3 126 4.53E-8 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CIG75_RS12730 7b6795cf29b491c368c7d3cfaa0ef738 130 SUPERFAMILY SSF160719 23 105 2.75E-10 T 28-03-2018 CIG75_RS12730 7b6795cf29b491c368c7d3cfaa0ef738 130 Gene3D G3DSA:3.10.450.40 10 127 2.9E-13 T 28-03-2018 CIG75_RS07650 1386fdc193fc1b63ed9f4736ce02c725 282 SUPERFAMILY SSF47090 213 271 1.7E-19 T 28-03-2018 IPR002477 Peptidoglycan binding-like CIG75_RS07650 1386fdc193fc1b63ed9f4736ce02c725 282 Gene3D G3DSA:2.40.440.10 82 198 1.7E-32 T 28-03-2018 CIG75_RS07650 1386fdc193fc1b63ed9f4736ce02c725 282 SUPERFAMILY SSF47090 8 72 4.19E-19 T 28-03-2018 IPR002477 Peptidoglycan binding-like CIG75_RS07650 1386fdc193fc1b63ed9f4736ce02c725 282 Gene3D G3DSA:1.10.101.10 6 74 1.3E-20 T 28-03-2018 IPR002477 Peptidoglycan binding-like CIG75_RS07650 1386fdc193fc1b63ed9f4736ce02c725 282 Pfam PF03734 L,D-transpeptidase catalytic domain 89 197 1.7E-21 T 28-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 CIG75_RS07650 1386fdc193fc1b63ed9f4736ce02c725 282 Gene3D G3DSA:1.10.101.10 199 277 4.8E-20 T 28-03-2018 IPR002477 Peptidoglycan binding-like CIG75_RS07650 1386fdc193fc1b63ed9f4736ce02c725 282 Pfam PF01471 Putative peptidoglycan binding domain 214 269 2.4E-18 T 28-03-2018 IPR002477 Peptidoglycan binding-like CIG75_RS07650 1386fdc193fc1b63ed9f4736ce02c725 282 Pfam PF01471 Putative peptidoglycan binding domain 16 72 1.2E-16 T 28-03-2018 IPR002477 Peptidoglycan binding-like CIG75_RS07650 1386fdc193fc1b63ed9f4736ce02c725 282 SUPERFAMILY SSF141523 86 198 1.24E-35 T 28-03-2018 CIG75_RS13590 689ba915b1e1778280a8e60695f10303 447 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 116 322 2.5E-79 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CIG75_RS13590 689ba915b1e1778280a8e60695f10303 447 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 1.2E-43 T 28-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CIG75_RS13590 689ba915b1e1778280a8e60695f10303 447 SUPERFAMILY SSF52440 1 113 1.51E-47 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CIG75_RS13590 689ba915b1e1778280a8e60695f10303 447 Gene3D G3DSA:3.30.470.20 210 444 1.5E-103 T 28-03-2018 CIG75_RS13590 689ba915b1e1778280a8e60695f10303 447 SUPERFAMILY SSF56059 83 350 1.73E-71 T 28-03-2018 CIG75_RS13590 689ba915b1e1778280a8e60695f10303 447 Pfam PF02785 Biotin carboxylase C-terminal domain 336 441 2.5E-36 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CIG75_RS13590 689ba915b1e1778280a8e60695f10303 447 Gene3D G3DSA:3.40.50.20 1 123 6.8E-55 T 28-03-2018 CIG75_RS13590 689ba915b1e1778280a8e60695f10303 447 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CIG75_RS13590 689ba915b1e1778280a8e60695f10303 447 Gene3D G3DSA:3.30.1490.20 124 209 1.1E-21 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CIG75_RS13590 689ba915b1e1778280a8e60695f10303 447 SMART SM00878 336 441 1.1E-51 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CIG75_RS13590 689ba915b1e1778280a8e60695f10303 447 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CIG75_RS13590 689ba915b1e1778280a8e60695f10303 447 SUPERFAMILY SSF51246 331 445 8.89E-39 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CIG75_RS08360 c71bbe2a8eedf15043e3ac5a88389fa6 162 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 3 144 1.4E-36 T 28-03-2018 IPR001453 MoaB/Mog domain CIG75_RS08360 c71bbe2a8eedf15043e3ac5a88389fa6 162 SUPERFAMILY SSF53218 2 155 5.1E-47 T 28-03-2018 IPR001453 MoaB/Mog domain CIG75_RS08360 c71bbe2a8eedf15043e3ac5a88389fa6 162 Gene3D G3DSA:3.40.980.10 1 161 7.0E-42 T 28-03-2018 IPR001453 MoaB/Mog domain CIG75_RS08360 c71bbe2a8eedf15043e3ac5a88389fa6 162 Pfam PF00994 Probable molybdopterin binding domain 6 149 1.5E-34 T 28-03-2018 IPR001453 MoaB/Mog domain CIG75_RS08360 c71bbe2a8eedf15043e3ac5a88389fa6 162 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 66 79 - T 28-03-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 CIG75_RS08360 c71bbe2a8eedf15043e3ac5a88389fa6 162 SMART SM00852 6 150 6.4E-30 T 28-03-2018 IPR001453 MoaB/Mog domain CIG75_RS01170 982db8fafd540a2d9108b8717d693649 314 SMART SM00283 53 314 6.6E-36 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CIG75_RS01170 982db8fafd540a2d9108b8717d693649 314 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 126 270 2.0E-39 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CIG75_RS01170 982db8fafd540a2d9108b8717d693649 314 SUPERFAMILY SSF58104 34 297 1.83E-54 T 28-03-2018 CIG75_RS01170 982db8fafd540a2d9108b8717d693649 314 Gene3D G3DSA:1.10.287.950 61 275 8.5E-45 T 28-03-2018 CIG75_RS14110 adf4e35600dcef253ca01bff6901511f 96 Pfam PF06949 Protein of unknown function (DUF1292) 25 94 5.2E-14 T 28-03-2018 IPR009711 Uncharacterised protein family UPF0473 CIG75_RS13540 86c37223ec437f58f1be4b123487ce56 339 Gene3D G3DSA:3.20.20.70 1 334 7.4E-119 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CIG75_RS13540 86c37223ec437f58f1be4b123487ce56 339 SUPERFAMILY SSF51395 2 326 1.47E-114 T 28-03-2018 CIG75_RS13540 86c37223ec437f58f1be4b123487ce56 339 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 4 321 2.2E-84 T 28-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CIG75_RS16160 9c3b415470c1fdf02d997ccf71a9224d 243 SUPERFAMILY SSF54106 78 122 7.98E-11 T 28-03-2018 IPR018392 LysM domain CIG75_RS16160 9c3b415470c1fdf02d997ccf71a9224d 243 SMART SM00257 78 122 5.7E-13 T 28-03-2018 IPR018392 LysM domain CIG75_RS16160 9c3b415470c1fdf02d997ccf71a9224d 243 SUPERFAMILY SSF50685 159 218 6.63E-10 T 28-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CIG75_RS16160 9c3b415470c1fdf02d997ccf71a9224d 243 Pfam PF06725 3D domain 176 237 1.2E-17 T 28-03-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 CIG75_RS16160 9c3b415470c1fdf02d997ccf71a9224d 243 Gene3D G3DSA:2.40.40.10 70 239 6.3E-37 T 28-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CIG75_RS16160 9c3b415470c1fdf02d997ccf71a9224d 243 Pfam PF01476 LysM domain 79 122 7.1E-13 T 28-03-2018 IPR018392 LysM domain CIG75_RS10460 fb406208e6f3dd5e2a10239f2256d68f 1080 Gene3D G3DSA:1.10.1200.10 993 1059 6.3E-18 T 28-03-2018 CIG75_RS10460 fb406208e6f3dd5e2a10239f2256d68f 1080 Gene3D G3DSA:2.30.38.10 791 870 2.5E-20 T 28-03-2018 CIG75_RS10460 fb406208e6f3dd5e2a10239f2256d68f 1080 SUPERFAMILY SSF47336 979 1052 2.75E-16 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10460 fb406208e6f3dd5e2a10239f2256d68f 1080 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 500 900 4.2E-123 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS10460 fb406208e6f3dd5e2a10239f2256d68f 1080 SUPERFAMILY SSF52777 20 196 1.56E-48 T 28-03-2018 CIG75_RS10460 fb406208e6f3dd5e2a10239f2256d68f 1080 SUPERFAMILY SSF56801 439 1000 2.49E-152 T 28-03-2018 CIG75_RS10460 fb406208e6f3dd5e2a10239f2256d68f 1080 Gene3D G3DSA:3.40.50.980 470 626 1.7E-48 T 28-03-2018 CIG75_RS10460 fb406208e6f3dd5e2a10239f2256d68f 1080 Gene3D G3DSA:3.40.50.980 627 789 3.5E-32 T 28-03-2018 CIG75_RS10460 fb406208e6f3dd5e2a10239f2256d68f 1080 Gene3D G3DSA:3.30.559.10 4 218 5.4E-41 T 28-03-2018 CIG75_RS10460 fb406208e6f3dd5e2a10239f2256d68f 1080 Pfam PF00668 Condensation domain 18 458 6.2E-117 T 28-03-2018 IPR001242 Condensation domain CIG75_RS10460 fb406208e6f3dd5e2a10239f2256d68f 1080 SUPERFAMILY SSF52777 204 463 1.11E-69 T 28-03-2018 CIG75_RS10460 fb406208e6f3dd5e2a10239f2256d68f 1080 ProSitePatterns PS00455 Putative AMP-binding domain signature. 621 632 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS10460 fb406208e6f3dd5e2a10239f2256d68f 1080 Pfam PF00550 Phosphopantetheine attachment site 988 1051 2.0E-8 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10460 fb406208e6f3dd5e2a10239f2256d68f 1080 Gene3D G3DSA:3.30.300.30 872 992 5.2E-38 T 28-03-2018 CIG75_RS10460 fb406208e6f3dd5e2a10239f2256d68f 1080 Pfam PF00501 AMP-binding enzyme 480 877 4.1E-101 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS10460 fb406208e6f3dd5e2a10239f2256d68f 1080 Pfam PF13193 AMP-binding enzyme C-terminal domain 885 959 3.5E-10 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS20045 6bd5a112fed2cf7d8b4a2b5fae61454c 317 SMART SM00871 153 315 3.6E-33 T 28-03-2018 IPR010499 Bacterial transcription activator, effector binding CIG75_RS20045 6bd5a112fed2cf7d8b4a2b5fae61454c 317 Gene3D G3DSA:1.10.10.60 82 138 2.6E-14 T 28-03-2018 CIG75_RS20045 6bd5a112fed2cf7d8b4a2b5fae61454c 317 Pfam PF14526 Integron-associated effector binding protein 160 314 1.4E-27 T 28-03-2018 IPR029441 Integron-associated effector binding protein CIG75_RS20045 6bd5a112fed2cf7d8b4a2b5fae61454c 317 Pfam PF12833 Helix-turn-helix domain 49 128 8.6E-23 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CIG75_RS20045 6bd5a112fed2cf7d8b4a2b5fae61454c 317 SUPERFAMILY SSF46689 79 137 1.3E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CIG75_RS20045 6bd5a112fed2cf7d8b4a2b5fae61454c 317 SUPERFAMILY SSF55136 154 316 9.16E-25 T 28-03-2018 CIG75_RS20045 6bd5a112fed2cf7d8b4a2b5fae61454c 317 Gene3D G3DSA:3.20.80.10 139 315 2.6E-43 T 28-03-2018 IPR011256 Regulatory factor, effector binding domain CIG75_RS20045 6bd5a112fed2cf7d8b4a2b5fae61454c 317 SUPERFAMILY SSF46689 27 77 2.24E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CIG75_RS20045 6bd5a112fed2cf7d8b4a2b5fae61454c 317 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 95 110 1.5E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CIG75_RS20045 6bd5a112fed2cf7d8b4a2b5fae61454c 317 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 110 126 1.5E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CIG75_RS20045 6bd5a112fed2cf7d8b4a2b5fae61454c 317 Gene3D G3DSA:1.10.10.60 26 81 1.5E-12 T 28-03-2018 CIG75_RS20045 6bd5a112fed2cf7d8b4a2b5fae61454c 317 SMART SM00342 43 126 8.9E-31 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CIG75_RS20045 6bd5a112fed2cf7d8b4a2b5fae61454c 317 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 80 122 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CIG75_RS00720 22f1da96324601c810957786a74828ef 113 Pfam PF00893 Small Multidrug Resistance protein 4 92 4.6E-18 T 28-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 CIG75_RS00720 22f1da96324601c810957786a74828ef 113 SUPERFAMILY SSF103481 7 103 3.27E-13 T 28-03-2018 CIG75_RS03465 edeae4dfd0c390d13f005bc2aed2af4b 536 SUPERFAMILY SSF56235 5 536 1.58E-182 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CIG75_RS03465 edeae4dfd0c390d13f005bc2aed2af4b 536 Pfam PF01019 Gamma-glutamyltranspeptidase 37 531 1.3E-159 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CIG75_RS03465 edeae4dfd0c390d13f005bc2aed2af4b 536 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 44 69 2.5E-41 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CIG75_RS03465 edeae4dfd0c390d13f005bc2aed2af4b 536 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 379 397 2.5E-41 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CIG75_RS03465 edeae4dfd0c390d13f005bc2aed2af4b 536 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 410 425 2.5E-41 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CIG75_RS03465 edeae4dfd0c390d13f005bc2aed2af4b 536 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 131 150 2.5E-41 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CIG75_RS03465 edeae4dfd0c390d13f005bc2aed2af4b 536 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 235 251 2.5E-41 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CIG75_RS03465 edeae4dfd0c390d13f005bc2aed2af4b 536 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 264 283 2.5E-41 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CIG75_RS03465 edeae4dfd0c390d13f005bc2aed2af4b 536 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 434 451 2.5E-41 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CIG75_RS03465 edeae4dfd0c390d13f005bc2aed2af4b 536 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 355 373 2.5E-41 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CIG75_RS03465 edeae4dfd0c390d13f005bc2aed2af4b 536 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 113 131 2.5E-41 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CIG75_RS08040 b3a2bf4fec1b6321acd6b3055e2afee9 326 SUPERFAMILY SSF50685 265 316 2.44E-9 T 28-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CIG75_RS08040 b3a2bf4fec1b6321acd6b3055e2afee9 326 Gene3D G3DSA:2.20.230.10 134 221 2.6E-17 T 28-03-2018 CIG75_RS08040 b3a2bf4fec1b6321acd6b3055e2afee9 326 SMART SM01208 146 223 3.8E-23 T 28-03-2018 IPR011098 G5 domain CIG75_RS08040 b3a2bf4fec1b6321acd6b3055e2afee9 326 Gene3D G3DSA:2.40.40.10 222 325 2.4E-31 T 28-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CIG75_RS08040 b3a2bf4fec1b6321acd6b3055e2afee9 326 Pfam PF07501 G5 domain 150 222 4.7E-18 T 28-03-2018 IPR011098 G5 domain CIG75_RS08040 b3a2bf4fec1b6321acd6b3055e2afee9 326 Pfam PF03990 Domain of unknown function (DUF348) 101 133 8.2E-6 T 28-03-2018 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 CIG75_RS08040 b3a2bf4fec1b6321acd6b3055e2afee9 326 Pfam PF03990 Domain of unknown function (DUF348) 34 73 1.9E-7 T 28-03-2018 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 CIG75_RS08040 b3a2bf4fec1b6321acd6b3055e2afee9 326 Pfam PF06725 3D domain 266 326 1.3E-21 T 28-03-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 CIG75_RS01180 5cb06b53d4ef1b09823b3d273921667a 111 Pfam PF06127 Protein of unknown function (DUF962) 3 97 1.8E-29 T 28-03-2018 IPR009305 Protein of unknown function DUF962 CIG75_RS17745 bb175bde5ddebcd49a195d842f080eae 264 SUPERFAMILY SSF53335 5 235 2.55E-37 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CIG75_RS17745 bb175bde5ddebcd49a195d842f080eae 264 Pfam PF08241 Methyltransferase domain 39 136 1.3E-21 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CIG75_RS17745 bb175bde5ddebcd49a195d842f080eae 264 Gene3D G3DSA:3.40.50.150 4 262 2.5E-36 T 28-03-2018 CIG75_RS17245 14d9a734915134f8ea29f7b258164aa5 285 SUPERFAMILY SSF52540 8 211 7.27E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS17245 14d9a734915134f8ea29f7b258164aa5 285 Pfam PF00005 ABC transporter 18 159 2.5E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS17245 14d9a734915134f8ea29f7b258164aa5 285 SMART SM00382 26 205 1.5E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS17245 14d9a734915134f8ea29f7b258164aa5 285 Gene3D G3DSA:3.40.50.300 2 248 6.9E-60 T 28-03-2018 CIG75_RS13210 97f4d9924ee5154b60a8a5093a5f3621 259 Gene3D G3DSA:1.10.10.10 111 163 1.3E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS13210 97f4d9924ee5154b60a8a5093a5f3621 259 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 227 253 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS13210 97f4d9924ee5154b60a8a5093a5f3621 259 TIGRFAM TIGR02850 spore_sigG: RNA polymerase sigma-G factor 4 257 1.5E-151 T 28-03-2018 IPR014212 RNA polymerase sigma-G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS13210 97f4d9924ee5154b60a8a5093a5f3621 259 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 37 255 3.1E-36 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS13210 97f4d9924ee5154b60a8a5093a5f3621 259 SUPERFAMILY SSF88946 6 110 1.15E-33 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS13210 97f4d9924ee5154b60a8a5093a5f3621 259 PRINTS PR00046 Major sigma-70 factor signature 227 242 8.2E-13 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS13210 97f4d9924ee5154b60a8a5093a5f3621 259 PRINTS PR00046 Major sigma-70 factor signature 242 253 8.2E-13 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS13210 97f4d9924ee5154b60a8a5093a5f3621 259 PRINTS PR00046 Major sigma-70 factor signature 90 98 8.2E-13 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS13210 97f4d9924ee5154b60a8a5093a5f3621 259 PRINTS PR00046 Major sigma-70 factor signature 210 222 8.2E-13 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS13210 97f4d9924ee5154b60a8a5093a5f3621 259 PRINTS PR00046 Major sigma-70 factor signature 66 79 8.2E-13 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS13210 97f4d9924ee5154b60a8a5093a5f3621 259 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 66 79 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS13210 97f4d9924ee5154b60a8a5093a5f3621 259 PIRSF PIRSF000770 16 259 7.3E-33 T 28-03-2018 CIG75_RS13210 97f4d9924ee5154b60a8a5093a5f3621 259 SUPERFAMILY SSF88659 175 258 3.18E-17 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS13210 97f4d9924ee5154b60a8a5093a5f3621 259 Gene3D G3DSA:1.10.10.10 195 257 2.1E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS13210 97f4d9924ee5154b60a8a5093a5f3621 259 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 37 255 1.1E-83 T 28-03-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS13210 97f4d9924ee5154b60a8a5093a5f3621 259 Pfam PF04542 Sigma-70 region 2 42 110 1.0E-17 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS13210 97f4d9924ee5154b60a8a5093a5f3621 259 SUPERFAMILY SSF88659 114 190 4.8E-15 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS13210 97f4d9924ee5154b60a8a5093a5f3621 259 Pfam PF04545 Sigma-70, region 4 206 253 4.5E-15 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS13210 97f4d9924ee5154b60a8a5093a5f3621 259 Gene3D G3DSA:1.10.601.10 11 110 4.5E-32 T 28-03-2018 CIG75_RS18770 27a931466d8c5924eb40a9755c56b300 421 SUPERFAMILY SSF63867 342 415 5.49E-7 T 28-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CIG75_RS18770 27a931466d8c5924eb40a9755c56b300 421 SUPERFAMILY SSF63882 5 187 3.53E-47 T 28-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CIG75_RS18770 27a931466d8c5924eb40a9755c56b300 421 Pfam PF00994 Probable molybdopterin binding domain 201 329 2.2E-28 T 28-03-2018 IPR001453 MoaB/Mog domain CIG75_RS18770 27a931466d8c5924eb40a9755c56b300 421 Pfam PF03453 MoeA N-terminal region (domain I and II) 7 179 4.1E-38 T 28-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CIG75_RS18770 27a931466d8c5924eb40a9755c56b300 421 Pfam PF03454 MoeA C-terminal region (domain IV) 356 414 1.9E-6 T 28-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CIG75_RS18770 27a931466d8c5924eb40a9755c56b300 421 SUPERFAMILY SSF53218 189 334 3.4E-41 T 28-03-2018 IPR001453 MoaB/Mog domain CIG75_RS18770 27a931466d8c5924eb40a9755c56b300 421 Gene3D G3DSA:2.40.340.10 341 416 2.5E-8 T 28-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CIG75_RS18770 27a931466d8c5924eb40a9755c56b300 421 Gene3D G3DSA:3.40.980.10 162 340 5.7E-52 T 28-03-2018 IPR001453 MoaB/Mog domain CIG75_RS18770 27a931466d8c5924eb40a9755c56b300 421 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 188 325 1.5E-30 T 28-03-2018 IPR001453 MoaB/Mog domain CIG75_RS18770 27a931466d8c5924eb40a9755c56b300 421 Gene3D G3DSA:3.90.105.10 23 57 2.9E-12 T 28-03-2018 CIG75_RS18770 27a931466d8c5924eb40a9755c56b300 421 Gene3D G3DSA:2.170.190.11 58 153 2.3E-27 T 28-03-2018 CIG75_RS18770 27a931466d8c5924eb40a9755c56b300 421 SMART SM00852 192 330 2.5E-41 T 28-03-2018 IPR001453 MoaB/Mog domain CIG75_RS06305 cbac7f9226ffe79a0010b712eed5a110 323 SUPERFAMILY SSF56112 11 295 1.6E-35 T 28-03-2018 IPR011009 Protein kinase-like domain CIG75_RS06305 cbac7f9226ffe79a0010b712eed5a110 323 Pfam PF01636 Phosphotransferase enzyme family 85 263 1.2E-14 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CIG75_RS06305 cbac7f9226ffe79a0010b712eed5a110 323 Gene3D G3DSA:3.30.200.20 4 103 3.6E-7 T 28-03-2018 CIG75_RS06305 cbac7f9226ffe79a0010b712eed5a110 323 Gene3D G3DSA:3.90.1200.10 104 321 9.0E-24 T 28-03-2018 CIG75_RS02205 951aa7c0f764898e4d0dfef560e5b0e6 397 Gene3D G3DSA:3.30.300.10 145 245 1.1E-48 T 28-03-2018 CIG75_RS02205 951aa7c0f764898e4d0dfef560e5b0e6 397 Gene3D G3DSA:3.30.300.10 12 144 6.5E-45 T 28-03-2018 CIG75_RS02205 951aa7c0f764898e4d0dfef560e5b0e6 397 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 128 138 - T 28-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CIG75_RS02205 951aa7c0f764898e4d0dfef560e5b0e6 397 SUPERFAMILY SSF55973 122 244 5.1E-53 T 28-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CIG75_RS02205 951aa7c0f764898e4d0dfef560e5b0e6 397 SUPERFAMILY SSF55973 245 394 6.67E-72 T 28-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CIG75_RS02205 951aa7c0f764898e4d0dfef560e5b0e6 397 Pfam PF02772 S-adenosylmethionine synthetase, central domain 127 243 1.9E-49 T 28-03-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CIG75_RS02205 951aa7c0f764898e4d0dfef560e5b0e6 397 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 245 384 2.4E-72 T 28-03-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CIG75_RS02205 951aa7c0f764898e4d0dfef560e5b0e6 397 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 5 102 6.5E-45 T 28-03-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CIG75_RS02205 951aa7c0f764898e4d0dfef560e5b0e6 397 Gene3D G3DSA:3.30.300.10 258 397 5.4E-51 T 28-03-2018 CIG75_RS02205 951aa7c0f764898e4d0dfef560e5b0e6 397 PIRSF PIRSF000497 1 395 2.0E-179 T 28-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CIG75_RS02205 951aa7c0f764898e4d0dfef560e5b0e6 397 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 3 395 60.165 T 28-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CIG75_RS02205 951aa7c0f764898e4d0dfef560e5b0e6 397 SUPERFAMILY SSF55973 4 110 6.28E-48 T 28-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CIG75_RS02205 951aa7c0f764898e4d0dfef560e5b0e6 397 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 271 279 - T 28-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CIG75_RS02205 951aa7c0f764898e4d0dfef560e5b0e6 397 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 6 393 3.8E-188 T 28-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CIG75_RS06995 8d5fb70aeb0320da154ec2a72ab984a0 579 Gene3D G3DSA:3.40.710.10 250 577 4.1E-82 T 28-03-2018 CIG75_RS06995 8d5fb70aeb0320da154ec2a72ab984a0 579 Gene3D G3DSA:3.90.1310.10 24 242 6.5E-21 T 28-03-2018 CIG75_RS06995 8d5fb70aeb0320da154ec2a72ab984a0 579 SUPERFAMILY SSF56601 431 568 1.5E-76 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CIG75_RS06995 8d5fb70aeb0320da154ec2a72ab984a0 579 SUPERFAMILY SSF56601 197 404 1.5E-76 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CIG75_RS06995 8d5fb70aeb0320da154ec2a72ab984a0 579 Pfam PF00905 Penicillin binding protein transpeptidase domain 271 572 1.5E-62 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CIG75_RS06995 8d5fb70aeb0320da154ec2a72ab984a0 579 SUPERFAMILY SSF56519 53 235 9.03E-18 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CIG75_RS06995 8d5fb70aeb0320da154ec2a72ab984a0 579 Pfam PF03717 Penicillin-binding Protein dimerisation domain 60 231 3.1E-8 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CIG75_RS01930 4d4f9f93af2a9032be2ba1a904f55fca 177 Hamap MF_01416 ATP synthase subunit delta [atpD]. 2 177 19.916 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CIG75_RS01930 4d4f9f93af2a9032be2ba1a904f55fca 177 Pfam PF00213 ATP synthase delta (OSCP) subunit 6 175 2.0E-49 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CIG75_RS01930 4d4f9f93af2a9032be2ba1a904f55fca 177 SUPERFAMILY SSF47928 1 106 4.18E-25 T 28-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CIG75_RS01930 4d4f9f93af2a9032be2ba1a904f55fca 177 ProSitePatterns PS00389 ATP synthase delta (OSCP) subunit signature. 137 156 - T 28-03-2018 IPR020781 ATPase, OSCP/delta subunit, conserved site GO:0015986|GO:0016020|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CIG75_RS01930 4d4f9f93af2a9032be2ba1a904f55fca 177 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 6 175 5.5E-41 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CIG75_RS01930 4d4f9f93af2a9032be2ba1a904f55fca 177 PRINTS PR00125 ATP synthase delta subunit signature 86 100 6.9E-26 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CIG75_RS01930 4d4f9f93af2a9032be2ba1a904f55fca 177 PRINTS PR00125 ATP synthase delta subunit signature 6 25 6.9E-26 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CIG75_RS01930 4d4f9f93af2a9032be2ba1a904f55fca 177 PRINTS PR00125 ATP synthase delta subunit signature 135 150 6.9E-26 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CIG75_RS01930 4d4f9f93af2a9032be2ba1a904f55fca 177 PRINTS PR00125 ATP synthase delta subunit signature 75 86 6.9E-26 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CIG75_RS01930 4d4f9f93af2a9032be2ba1a904f55fca 177 PRINTS PR00125 ATP synthase delta subunit signature 150 168 6.9E-26 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CIG75_RS01930 4d4f9f93af2a9032be2ba1a904f55fca 177 Gene3D G3DSA:1.10.520.20 2 106 2.2E-25 T 28-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CIG75_RS14435 e9835a6c7f604fae146bff1342162479 214 Pfam PF00011 Hsp20/alpha crystallin family 112 209 3.1E-13 T 28-03-2018 IPR002068 Alpha crystallin/Hsp20 domain CIG75_RS14435 e9835a6c7f604fae146bff1342162479 214 SUPERFAMILY SSF49764 97 200 4.53E-20 T 28-03-2018 IPR008978 HSP20-like chaperone CIG75_RS14435 e9835a6c7f604fae146bff1342162479 214 Gene3D G3DSA:2.60.40.790 47 209 8.2E-26 T 28-03-2018 IPR008978 HSP20-like chaperone CIG75_RS14630 2d87230fe543832058e342d2540f512c 376 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 11 355 2.2E-78 T 28-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CIG75_RS14630 2d87230fe543832058e342d2540f512c 376 PIRSF PIRSF037489 5 376 1.8E-148 T 28-03-2018 IPR017221 GTP cyclohydrolase 1 type 2//Nif3, bacteria CIG75_RS14630 2d87230fe543832058e342d2540f512c 376 Gene3D G3DSA:3.40.1390.30 229 348 6.3E-13 T 28-03-2018 CIG75_RS14630 2d87230fe543832058e342d2540f512c 376 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 9 371 2.5E-67 T 28-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CIG75_RS14630 2d87230fe543832058e342d2540f512c 376 Gene3D G3DSA:3.40.1390.30 5 132 1.4E-38 T 28-03-2018 CIG75_RS14630 2d87230fe543832058e342d2540f512c 376 Gene3D G3DSA:3.30.70.120 137 228 2.5E-40 T 28-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal CIG75_RS14630 2d87230fe543832058e342d2540f512c 376 SUPERFAMILY SSF102705 8 375 2.22E-125 T 28-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CIG75_RS02600 7b16dae2aefe64bd9dc93fa07ffe1fe5 427 SUPERFAMILY SSF103473 8 411 2.35E-47 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS02600 7b16dae2aefe64bd9dc93fa07ffe1fe5 427 Pfam PF07690 Major Facilitator Superfamily 17 232 1.1E-19 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CIG75_RS02600 7b16dae2aefe64bd9dc93fa07ffe1fe5 427 Pfam PF07690 Major Facilitator Superfamily 270 414 2.9E-13 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CIG75_RS02600 7b16dae2aefe64bd9dc93fa07ffe1fe5 427 Gene3D G3DSA:1.20.1250.20 209 423 6.5E-19 T 28-03-2018 CIG75_RS02600 7b16dae2aefe64bd9dc93fa07ffe1fe5 427 Gene3D G3DSA:1.20.1250.20 2 203 4.8E-23 T 28-03-2018 CIG75_RS11090 6d65be3111e03a0c1d4fa4a571231258 324 PIRSF PIRSF002849 1 324 2.9E-116 T 28-03-2018 CIG75_RS11090 6d65be3111e03a0c1d4fa4a571231258 324 Gene3D G3DSA:3.40.50.300 23 192 1.2E-30 T 28-03-2018 CIG75_RS11090 6d65be3111e03a0c1d4fa4a571231258 324 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 42 175 5.5E-62 T 28-03-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 CIG75_RS11090 6d65be3111e03a0c1d4fa4a571231258 324 Gene3D G3DSA:1.10.8.300 205 322 1.2E-26 T 28-03-2018 CIG75_RS11090 6d65be3111e03a0c1d4fa4a571231258 324 SMART SM00382 39 183 0.0019 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS11090 6d65be3111e03a0c1d4fa4a571231258 324 SUPERFAMILY SSF52540 6 300 1.97E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS07525 c946cd11cbaeab2abefa7ccc913b10ae 682 Gene3D G3DSA:1.20.1560.10 2 415 1.3E-78 T 28-03-2018 CIG75_RS07525 c946cd11cbaeab2abefa7ccc913b10ae 682 ProSitePatterns PS00211 ABC transporters family signature. 566 580 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS07525 c946cd11cbaeab2abefa7ccc913b10ae 682 SUPERFAMILY SSF52540 420 665 2.25E-87 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS07525 c946cd11cbaeab2abefa7ccc913b10ae 682 SUPERFAMILY SSF90123 139 416 1.01E-86 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CIG75_RS07525 c946cd11cbaeab2abefa7ccc913b10ae 682 SUPERFAMILY SSF90123 20 59 1.01E-86 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CIG75_RS07525 c946cd11cbaeab2abefa7ccc913b10ae 682 Gene3D G3DSA:3.40.50.300 416 670 6.0E-74 T 28-03-2018 CIG75_RS07525 c946cd11cbaeab2abefa7ccc913b10ae 682 SMART SM00382 454 640 9.3E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS07525 c946cd11cbaeab2abefa7ccc913b10ae 682 Pfam PF00664 ABC transporter transmembrane region 134 382 1.3E-52 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CIG75_RS07525 c946cd11cbaeab2abefa7ccc913b10ae 682 Pfam PF00005 ABC transporter 445 594 8.3E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS11270 96c0108351fca65cd91b461cbc5f72f5 737 Gene3D G3DSA:3.40.50.300 262 465 6.9E-6 T 28-03-2018 CIG75_RS11270 96c0108351fca65cd91b461cbc5f72f5 737 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 519 644 1.6E-28 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CIG75_RS11270 96c0108351fca65cd91b461cbc5f72f5 737 SMART SM00382 515 647 1.5E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS11270 96c0108351fca65cd91b461cbc5f72f5 737 SUPERFAMILY SSF52540 245 441 8.08E-7 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS11270 96c0108351fca65cd91b461cbc5f72f5 737 Gene3D G3DSA:1.10.8.60 652 716 4.1E-5 T 28-03-2018 CIG75_RS11270 96c0108351fca65cd91b461cbc5f72f5 737 SUPERFAMILY SSF52540 470 703 2.6E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS11270 96c0108351fca65cd91b461cbc5f72f5 737 Gene3D G3DSA:3.40.50.300 466 651 4.2E-34 T 28-03-2018 CIG75_RS13455 5e7d95c593c72378c5a10ac29aa98d44 410 PIRSF PIRSF003101 1 410 1.7E-133 T 28-03-2018 IPR020823 Cell division protein FtsA GO:0007049 CIG75_RS13455 5e7d95c593c72378c5a10ac29aa98d44 410 Pfam PF02491 SHS2 domain inserted in FTSA 81 160 2.8E-28 T 28-03-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 CIG75_RS13455 5e7d95c593c72378c5a10ac29aa98d44 410 SUPERFAMILY SSF53067 196 357 3.44E-35 T 28-03-2018 CIG75_RS13455 5e7d95c593c72378c5a10ac29aa98d44 410 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 6 369 3.2E-116 T 28-03-2018 IPR020823 Cell division protein FtsA GO:0007049 CIG75_RS13455 5e7d95c593c72378c5a10ac29aa98d44 410 SUPERFAMILY SSF53067 6 194 1.25E-56 T 28-03-2018 CIG75_RS13455 5e7d95c593c72378c5a10ac29aa98d44 410 Gene3D G3DSA:3.30.420.40 1 184 1.8E-32 T 28-03-2018 CIG75_RS13455 5e7d95c593c72378c5a10ac29aa98d44 410 SMART SM00842 7 194 3.3E-91 T 28-03-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 CIG75_RS13455 5e7d95c593c72378c5a10ac29aa98d44 410 Pfam PF14450 Cell division protein FtsA 9 187 8.0E-11 T 28-03-2018 CIG75_RS13455 5e7d95c593c72378c5a10ac29aa98d44 410 Pfam PF14450 Cell division protein FtsA 206 344 1.6E-18 T 28-03-2018 CIG75_RS13455 5e7d95c593c72378c5a10ac29aa98d44 410 Hamap MF_02033 Cell division protein FtsA [ftsA]. 3 410 29.323 T 28-03-2018 IPR020823 Cell division protein FtsA GO:0007049 CIG75_RS13455 5e7d95c593c72378c5a10ac29aa98d44 410 Gene3D G3DSA:3.30.420.40 204 349 4.3E-22 T 28-03-2018 CIG75_RS05300 06f51edda622ef7c0ce76cd3bc646e24 409 Gene3D G3DSA:3.40.640.10 46 303 4.3E-51 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CIG75_RS05300 06f51edda622ef7c0ce76cd3bc646e24 409 Pfam PF00155 Aminotransferase class I and II 32 385 3.2E-62 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CIG75_RS05300 06f51edda622ef7c0ce76cd3bc646e24 409 Gene3D G3DSA:3.90.1150.10 304 393 1.5E-23 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CIG75_RS05300 06f51edda622ef7c0ce76cd3bc646e24 409 SUPERFAMILY SSF53383 2 391 5.85E-104 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CIG75_RS19280 684e3fd20d1c5aa0a843a2b5167943a2 386 SMART SM00530 16 72 1.1E-7 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS19280 684e3fd20d1c5aa0a843a2b5167943a2 386 SUPERFAMILY SSF48452 279 380 2.12E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS19280 684e3fd20d1c5aa0a843a2b5167943a2 386 Gene3D G3DSA:1.10.260.40 5 78 1.8E-11 T 28-03-2018 CIG75_RS19280 684e3fd20d1c5aa0a843a2b5167943a2 386 SUPERFAMILY SSF48452 158 303 4.65E-17 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS19280 684e3fd20d1c5aa0a843a2b5167943a2 386 Pfam PF12844 Helix-turn-helix domain 14 77 4.5E-11 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS19280 684e3fd20d1c5aa0a843a2b5167943a2 386 Gene3D G3DSA:1.25.40.10 170 218 9.8E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS19280 684e3fd20d1c5aa0a843a2b5167943a2 386 Pfam PF13181 Tetratricopeptide repeat 235 264 0.0024 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS19280 684e3fd20d1c5aa0a843a2b5167943a2 386 Gene3D G3DSA:1.25.40.10 286 383 3.5E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS19280 684e3fd20d1c5aa0a843a2b5167943a2 386 Gene3D G3DSA:1.10.150.200 220 285 8.3E-6 T 28-03-2018 CIG75_RS19280 684e3fd20d1c5aa0a843a2b5167943a2 386 Gene3D G3DSA:1.25.40.10 79 169 2.2E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS19280 684e3fd20d1c5aa0a843a2b5167943a2 386 SUPERFAMILY SSF47413 7 78 6.19E-11 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CIG75_RS19280 684e3fd20d1c5aa0a843a2b5167943a2 386 Pfam PF13176 Tetratricopeptide repeat 159 182 0.0075 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS19280 684e3fd20d1c5aa0a843a2b5167943a2 386 SMART SM00028 157 190 0.016 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS19280 684e3fd20d1c5aa0a843a2b5167943a2 386 SMART SM00028 234 267 34.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS19280 684e3fd20d1c5aa0a843a2b5167943a2 386 SMART SM00028 349 382 46.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS09000 e978ecd0c7c6092f37354214878c6284 179 SUPERFAMILY SSF51306 31 171 2.25E-43 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CIG75_RS09000 e978ecd0c7c6092f37354214878c6284 179 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 84 96 2.9E-14 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CIG75_RS09000 e978ecd0c7c6092f37354214878c6284 179 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 33 49 2.9E-14 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CIG75_RS09000 e978ecd0c7c6092f37354214878c6284 179 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 127 146 2.9E-14 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CIG75_RS09000 e978ecd0c7c6092f37354214878c6284 179 Gene3D G3DSA:2.10.109.10 29 179 2.1E-42 T 28-03-2018 CIG75_RS09000 e978ecd0c7c6092f37354214878c6284 179 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 16 170 2.6E-46 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CIG75_RS09000 e978ecd0c7c6092f37354214878c6284 179 Pfam PF00717 Peptidase S24-like 39 107 2.0E-17 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CIG75_RS09000 e978ecd0c7c6092f37354214878c6284 179 ProSitePatterns PS00501 Signal peptidases I serine active site. 42 49 - T 28-03-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 CIG75_RS05645 dcd71a95fd22db88739d0af784be3f78 160 Gene3D G3DSA:3.40.50.1010 13 151 6.8E-4 T 28-03-2018 IPR029060 PIN domain-like CIG75_RS01200 773fea61a2faa1e35498010702caaf1c 992 Pfam PF01391 Collagen triple helix repeat (20 copies) 106 163 1.4E-7 T 28-03-2018 IPR008160 Collagen triple helix repeat CIG75_RS01200 773fea61a2faa1e35498010702caaf1c 992 Pfam PF01391 Collagen triple helix repeat (20 copies) 760 818 9.2E-8 T 28-03-2018 IPR008160 Collagen triple helix repeat CIG75_RS01200 773fea61a2faa1e35498010702caaf1c 992 TIGRFAM TIGR03721 exospore_TM: BclB C-terminal domain 820 991 1.3E-61 T 28-03-2018 IPR021210 Exosporium BclB, C-terminal CIG75_RS01200 773fea61a2faa1e35498010702caaf1c 992 Gene3D G3DSA:2.160.20.50 627 706 3.7E-11 T 28-03-2018 CIG75_RS01200 773fea61a2faa1e35498010702caaf1c 992 Gene3D G3DSA:2.160.20.50 159 226 3.0E-10 T 28-03-2018 CIG75_RS01200 773fea61a2faa1e35498010702caaf1c 992 Gene3D G3DSA:2.160.20.50 536 607 2.5E-10 T 28-03-2018 CIG75_RS01200 773fea61a2faa1e35498010702caaf1c 992 Gene3D G3DSA:2.160.20.50 83 158 1.6E-15 T 28-03-2018 CIG75_RS01200 773fea61a2faa1e35498010702caaf1c 992 Gene3D G3DSA:2.160.20.50 755 824 4.5E-14 T 28-03-2018 CIG75_RS01200 773fea61a2faa1e35498010702caaf1c 992 Gene3D G3DSA:2.160.20.50 465 535 2.8E-13 T 28-03-2018 CIG75_RS01200 773fea61a2faa1e35498010702caaf1c 992 Gene3D G3DSA:2.160.20.50 357 439 7.0E-10 T 28-03-2018 CIG75_RS01295 fe6c167d4616b8c990fc4450bca66145 289 Gene3D G3DSA:1.10.510.10 98 287 6.4E-29 T 28-03-2018 CIG75_RS01295 fe6c167d4616b8c990fc4450bca66145 289 Pfam PF00069 Protein kinase domain 30 288 3.2E-32 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CIG75_RS01295 fe6c167d4616b8c990fc4450bca66145 289 SMART SM00219 30 252 6.7E-5 T 28-03-2018 IPR020635 Tyrosine-protein kinase, catalytic domain GO:0004713|GO:0006468 CIG75_RS01295 fe6c167d4616b8c990fc4450bca66145 289 Gene3D G3DSA:3.30.200.20 19 97 2.3E-17 T 28-03-2018 CIG75_RS01295 fe6c167d4616b8c990fc4450bca66145 289 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 36 59 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 CIG75_RS01295 fe6c167d4616b8c990fc4450bca66145 289 SUPERFAMILY SSF56112 12 257 5.59E-47 T 28-03-2018 IPR011009 Protein kinase-like domain CIG75_RS09190 c8912feb1cff4b9ec857bc9997ddb61f 360 Gene3D G3DSA:3.40.50.1110 34 244 1.2E-34 T 28-03-2018 CIG75_RS09190 c8912feb1cff4b9ec857bc9997ddb61f 360 SUPERFAMILY SSF55383 299 347 4.18E-8 T 28-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CIG75_RS09190 c8912feb1cff4b9ec857bc9997ddb61f 360 Pfam PF07833 Copper amine oxidase N-terminal domain 297 353 7.2E-6 T 28-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CIG75_RS09190 c8912feb1cff4b9ec857bc9997ddb61f 360 SUPERFAMILY SSF52266 36 244 8.32E-34 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CIG75_RS09190 c8912feb1cff4b9ec857bc9997ddb61f 360 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 42 234 1.8E-33 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CIG75_RS18135 91d0e00cca69f72ee4176f5803f61035 430 SUPERFAMILY SSF48452 188 343 2.28E-22 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS18135 91d0e00cca69f72ee4176f5803f61035 430 Pfam PF12844 Helix-turn-helix domain 6 66 8.3E-12 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS18135 91d0e00cca69f72ee4176f5803f61035 430 SMART SM00028 149 182 49.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS18135 91d0e00cca69f72ee4176f5803f61035 430 SMART SM00028 389 422 3.6 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS18135 91d0e00cca69f72ee4176f5803f61035 430 SMART SM00028 311 344 54.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS18135 91d0e00cca69f72ee4176f5803f61035 430 SMART SM00028 231 264 13.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS18135 91d0e00cca69f72ee4176f5803f61035 430 SMART SM00028 349 382 56.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS18135 91d0e00cca69f72ee4176f5803f61035 430 SMART SM00028 109 142 150.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS18135 91d0e00cca69f72ee4176f5803f61035 430 SMART SM00028 191 224 0.37 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS18135 91d0e00cca69f72ee4176f5803f61035 430 Gene3D G3DSA:1.25.40.10 159 204 1.2E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS18135 91d0e00cca69f72ee4176f5803f61035 430 SUPERFAMILY SSF48452 307 421 7.59E-15 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS18135 91d0e00cca69f72ee4176f5803f61035 430 Pfam PF13181 Tetratricopeptide repeat 232 260 0.041 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS18135 91d0e00cca69f72ee4176f5803f61035 430 Pfam PF13181 Tetratricopeptide repeat 390 414 1.1E-4 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS18135 91d0e00cca69f72ee4176f5803f61035 430 Gene3D G3DSA:1.25.40.10 205 254 1.2E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS18135 91d0e00cca69f72ee4176f5803f61035 430 SUPERFAMILY SSF81901 82 217 2.62E-12 T 28-03-2018 CIG75_RS18135 91d0e00cca69f72ee4176f5803f61035 430 Pfam PF13432 Tetratricopeptide repeat 316 379 0.005 T 28-03-2018 CIG75_RS18135 91d0e00cca69f72ee4176f5803f61035 430 SMART SM00530 8 62 5.8E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS18135 91d0e00cca69f72ee4176f5803f61035 430 Gene3D G3DSA:1.10.150.200 97 158 4.6E-5 T 28-03-2018 CIG75_RS18135 91d0e00cca69f72ee4176f5803f61035 430 Gene3D G3DSA:1.20.58.280 255 292 0.064 T 28-03-2018 CIG75_RS18135 91d0e00cca69f72ee4176f5803f61035 430 Pfam PF14559 Tetratricopeptide repeat 82 138 8.6E-6 T 28-03-2018 CIG75_RS18135 91d0e00cca69f72ee4176f5803f61035 430 Pfam PF13424 Tetratricopeptide repeat 151 217 2.5E-9 T 28-03-2018 CIG75_RS18135 91d0e00cca69f72ee4176f5803f61035 430 Gene3D G3DSA:1.25.40.10 377 425 1.2E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS18135 91d0e00cca69f72ee4176f5803f61035 430 Gene3D G3DSA:1.10.260.40 1 96 1.2E-18 T 28-03-2018 CIG75_RS18135 91d0e00cca69f72ee4176f5803f61035 430 Gene3D G3DSA:1.25.40.10 293 376 8.5E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS18135 91d0e00cca69f72ee4176f5803f61035 430 SUPERFAMILY SSF47413 2 67 2.0E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CIG75_RS05585 c5b33c614def651dd9c3f7c4df23c153 314 Gene3D G3DSA:3.90.110.10 150 313 5.7E-47 T 28-03-2018 CIG75_RS05585 c5b33c614def651dd9c3f7c4df23c153 314 SUPERFAMILY SSF51735 2 147 9.4E-49 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS05585 c5b33c614def651dd9c3f7c4df23c153 314 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 151 311 9.2E-26 T 28-03-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 CIG75_RS05585 c5b33c614def651dd9c3f7c4df23c153 314 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 7 147 2.1E-41 T 28-03-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 CIG75_RS05585 c5b33c614def651dd9c3f7c4df23c153 314 Gene3D G3DSA:3.40.50.720 7 149 1.0E-37 T 28-03-2018 CIG75_RS05585 c5b33c614def651dd9c3f7c4df23c153 314 TIGRFAM TIGR01763 MalateDH_bact: malate dehydrogenase, NAD-dependent 5 310 3.2E-153 T 28-03-2018 IPR011275 Malate dehydrogenase, type 3 GO:0016616|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 CIG75_RS05585 c5b33c614def651dd9c3f7c4df23c153 314 SUPERFAMILY SSF56327 151 310 1.73E-51 T 28-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 CIG75_RS05585 c5b33c614def651dd9c3f7c4df23c153 314 PIRSF PIRSF000102 2 313 1.4E-101 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CIG75_RS05585 c5b33c614def651dd9c3f7c4df23c153 314 PRINTS PR00086 L-lactate dehydrogenase signature 33 57 8.8E-31 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CIG75_RS05585 c5b33c614def651dd9c3f7c4df23c153 314 PRINTS PR00086 L-lactate dehydrogenase signature 121 141 8.8E-31 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CIG75_RS05585 c5b33c614def651dd9c3f7c4df23c153 314 PRINTS PR00086 L-lactate dehydrogenase signature 145 163 8.8E-31 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CIG75_RS05585 c5b33c614def651dd9c3f7c4df23c153 314 PRINTS PR00086 L-lactate dehydrogenase signature 175 188 8.8E-31 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CIG75_RS05585 c5b33c614def651dd9c3f7c4df23c153 314 PRINTS PR00086 L-lactate dehydrogenase signature 7 31 8.8E-31 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CIG75_RS05585 c5b33c614def651dd9c3f7c4df23c153 314 Hamap MF_00487 Malate dehydrogenase [mdh]. 5 312 46.486 T 28-03-2018 IPR011275 Malate dehydrogenase, type 3 GO:0016616|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 CIG75_RS03990 6725373a9aae688a335e874446c8c5f7 105 SUPERFAMILY SSF46689 7 101 5.2E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CIG75_RS03990 6725373a9aae688a335e874446c8c5f7 105 Gene3D G3DSA:1.10.10.60 12 102 1.9E-17 T 28-03-2018 CIG75_RS03990 6725373a9aae688a335e874446c8c5f7 105 Pfam PF01527 Transposase 6 93 2.1E-11 T 28-03-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 CIG75_RS20360 6725373a9aae688a335e874446c8c5f7 105 SUPERFAMILY SSF46689 7 101 5.2E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CIG75_RS20360 6725373a9aae688a335e874446c8c5f7 105 Gene3D G3DSA:1.10.10.60 12 102 1.9E-17 T 28-03-2018 CIG75_RS20360 6725373a9aae688a335e874446c8c5f7 105 Pfam PF01527 Transposase 6 93 2.1E-11 T 28-03-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 CIG75_RS03090 6725373a9aae688a335e874446c8c5f7 105 SUPERFAMILY SSF46689 7 101 5.2E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CIG75_RS03090 6725373a9aae688a335e874446c8c5f7 105 Gene3D G3DSA:1.10.10.60 12 102 1.9E-17 T 28-03-2018 CIG75_RS03090 6725373a9aae688a335e874446c8c5f7 105 Pfam PF01527 Transposase 6 93 2.1E-11 T 28-03-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 CIG75_RS13245 6725373a9aae688a335e874446c8c5f7 105 SUPERFAMILY SSF46689 7 101 5.2E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CIG75_RS13245 6725373a9aae688a335e874446c8c5f7 105 Gene3D G3DSA:1.10.10.60 12 102 1.9E-17 T 28-03-2018 CIG75_RS13245 6725373a9aae688a335e874446c8c5f7 105 Pfam PF01527 Transposase 6 93 2.1E-11 T 28-03-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 CIG75_RS17845 6725373a9aae688a335e874446c8c5f7 105 SUPERFAMILY SSF46689 7 101 5.2E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CIG75_RS17845 6725373a9aae688a335e874446c8c5f7 105 Gene3D G3DSA:1.10.10.60 12 102 1.9E-17 T 28-03-2018 CIG75_RS17845 6725373a9aae688a335e874446c8c5f7 105 Pfam PF01527 Transposase 6 93 2.1E-11 T 28-03-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 CIG75_RS14610 6725373a9aae688a335e874446c8c5f7 105 SUPERFAMILY SSF46689 7 101 5.2E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CIG75_RS14610 6725373a9aae688a335e874446c8c5f7 105 Gene3D G3DSA:1.10.10.60 12 102 1.9E-17 T 28-03-2018 CIG75_RS14610 6725373a9aae688a335e874446c8c5f7 105 Pfam PF01527 Transposase 6 93 2.1E-11 T 28-03-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 CIG75_RS18295 6725373a9aae688a335e874446c8c5f7 105 SUPERFAMILY SSF46689 7 101 5.2E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CIG75_RS18295 6725373a9aae688a335e874446c8c5f7 105 Gene3D G3DSA:1.10.10.60 12 102 1.9E-17 T 28-03-2018 CIG75_RS18295 6725373a9aae688a335e874446c8c5f7 105 Pfam PF01527 Transposase 6 93 2.1E-11 T 28-03-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 CIG75_RS04495 6725373a9aae688a335e874446c8c5f7 105 SUPERFAMILY SSF46689 7 101 5.2E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CIG75_RS04495 6725373a9aae688a335e874446c8c5f7 105 Gene3D G3DSA:1.10.10.60 12 102 1.9E-17 T 28-03-2018 CIG75_RS04495 6725373a9aae688a335e874446c8c5f7 105 Pfam PF01527 Transposase 6 93 2.1E-11 T 28-03-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 CIG75_RS01130 b5e4c847fd832ac756148d7d159eae80 65 Pfam PF09962 Uncharacterized conserved protein (DUF2196) 4 63 5.5E-31 T 28-03-2018 IPR019240 Protein of unknown function DUF2196 CIG75_RS01130 b5e4c847fd832ac756148d7d159eae80 65 TIGRFAM TIGR03833 TIGR03833: conserved hypothetical protein 4 63 4.3E-33 T 28-03-2018 IPR019240 Protein of unknown function DUF2196 CIG75_RS11970 829e9055a0bee993890e61a0e1ff8755 358 TIGRFAM TIGR01404 FlhB_rel_III: type III secretion protein, YscU/HrpY family 11 353 1.8E-98 T 28-03-2018 IPR006307 Type III exporter system, secretion apparatus protein BsaZ GO:0009306|GO:0016021 CIG75_RS11970 829e9055a0bee993890e61a0e1ff8755 358 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 306 327 3.6E-42 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CIG75_RS11970 829e9055a0bee993890e61a0e1ff8755 358 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 232 249 3.6E-42 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CIG75_RS11970 829e9055a0bee993890e61a0e1ff8755 358 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 276 291 3.6E-42 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CIG75_RS11970 829e9055a0bee993890e61a0e1ff8755 358 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 14 36 3.6E-42 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CIG75_RS11970 829e9055a0bee993890e61a0e1ff8755 358 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 212 230 3.6E-42 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CIG75_RS11970 829e9055a0bee993890e61a0e1ff8755 358 Gene3D G3DSA:3.40.1690.10 222 357 6.2E-56 T 28-03-2018 IPR029025 Type III secretion system substrate exporter, C-terminal CIG75_RS11970 829e9055a0bee993890e61a0e1ff8755 358 Pfam PF01312 FlhB HrpN YscU SpaS Family 11 351 1.9E-129 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CIG75_RS11970 829e9055a0bee993890e61a0e1ff8755 358 TIGRFAM TIGR00328 flhB: flagellar biosynthetic protein FlhB 12 357 4.8E-131 T 28-03-2018 IPR006136 Flagellar biosynthetic protein FlhB GO:0015031|GO:0016021|GO:0044780 CIG75_RS11970 829e9055a0bee993890e61a0e1ff8755 358 SUPERFAMILY SSF160544 248 355 1.24E-40 T 28-03-2018 IPR029025 Type III secretion system substrate exporter, C-terminal CIG75_RS04065 27bff7d840a844abe474fe4759ebe2c8 211 Gene3D G3DSA:1.10.10.10 128 210 2.8E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS04065 27bff7d840a844abe474fe4759ebe2c8 211 SUPERFAMILY SSF52172 2 132 1.99E-34 T 28-03-2018 IPR011006 CheY-like superfamily CIG75_RS04065 27bff7d840a844abe474fe4759ebe2c8 211 Gene3D G3DSA:3.40.50.2300 2 127 3.6E-34 T 28-03-2018 CIG75_RS04065 27bff7d840a844abe474fe4759ebe2c8 211 SMART SM00448 3 116 1.1E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CIG75_RS04065 27bff7d840a844abe474fe4759ebe2c8 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 179 5.6E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CIG75_RS04065 27bff7d840a844abe474fe4759ebe2c8 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 163 5.6E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CIG75_RS04065 27bff7d840a844abe474fe4759ebe2c8 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 191 5.6E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CIG75_RS04065 27bff7d840a844abe474fe4759ebe2c8 211 ProSitePatterns PS00622 LuxR-type HTH domain signature. 163 190 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CIG75_RS04065 27bff7d840a844abe474fe4759ebe2c8 211 Pfam PF00072 Response regulator receiver domain 5 117 1.5E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CIG75_RS04065 27bff7d840a844abe474fe4759ebe2c8 211 SMART SM00421 146 203 5.4E-24 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CIG75_RS04065 27bff7d840a844abe474fe4759ebe2c8 211 Pfam PF00196 Bacterial regulatory proteins, luxR family 148 203 1.1E-22 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CIG75_RS04065 27bff7d840a844abe474fe4759ebe2c8 211 SUPERFAMILY SSF46894 140 208 6.8E-23 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CIG75_RS07800 122a2923190b0de7e3875f7b05dcaf0d 331 SMART SM00909 229 313 6.7E-8 T 28-03-2018 IPR019606 GerMN domain CIG75_RS07800 122a2923190b0de7e3875f7b05dcaf0d 331 SMART SM00909 74 166 1.3E-22 T 28-03-2018 IPR019606 GerMN domain CIG75_RS07800 122a2923190b0de7e3875f7b05dcaf0d 331 Gene3D G3DSA:3.40.190.10 1 312 3.3E-4 T 28-03-2018 CIG75_RS07800 122a2923190b0de7e3875f7b05dcaf0d 331 Pfam PF10646 Sporulation and spore germination 50 160 2.6E-22 T 28-03-2018 IPR019606 GerMN domain CIG75_RS07800 122a2923190b0de7e3875f7b05dcaf0d 331 Pfam PF10646 Sporulation and spore germination 198 306 3.1E-11 T 28-03-2018 IPR019606 GerMN domain CIG75_RS03585 5ebd745f48abb853d4d0ed485f62fc45 220 SUPERFAMILY SSF50800 2 210 1.2E-67 T 28-03-2018 IPR011037 Pyruvate kinase-like, insert domain CIG75_RS03585 5ebd745f48abb853d4d0ed485f62fc45 220 Gene3D G3DSA:2.40.33.20 1 220 4.7E-51 T 28-03-2018 CIG75_RS03585 5ebd745f48abb853d4d0ed485f62fc45 220 Pfam PF03473 MOSC domain 49 158 2.0E-22 T 28-03-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 CIG75_RS08730 8dca9fb0aa484ae61af9c9ae3306ac82 501 PIRSF PIRSF005690 15 501 6.2E-135 T 28-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 CIG75_RS08730 8dca9fb0aa484ae61af9c9ae3306ac82 501 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 37 489 1.1E-154 T 28-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 CIG75_RS04260 0e4fa36c97b322993158b7311d38dd33 656 Pfam PF00350 Dynamin family 49 274 8.9E-40 T 28-03-2018 IPR022812 Dynamin superfamily CIG75_RS04260 0e4fa36c97b322993158b7311d38dd33 656 Gene3D G3DSA:3.40.50.300 24 519 2.6E-42 T 28-03-2018 CIG75_RS04260 0e4fa36c97b322993158b7311d38dd33 656 SUPERFAMILY SSF52540 165 313 3.77E-33 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS04260 0e4fa36c97b322993158b7311d38dd33 656 SUPERFAMILY SSF52540 36 99 3.77E-33 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS14965 532032acbda5768a019886c2b0a49c23 276 Pfam PF00753 Metallo-beta-lactamase superfamily 21 191 9.9E-28 T 28-03-2018 IPR001279 Metallo-beta-lactamase CIG75_RS14965 532032acbda5768a019886c2b0a49c23 276 SMART SM00849 22 191 8.8E-36 T 28-03-2018 IPR001279 Metallo-beta-lactamase CIG75_RS14965 532032acbda5768a019886c2b0a49c23 276 SUPERFAMILY SSF56281 1 264 1.57E-60 T 28-03-2018 IPR001279 Metallo-beta-lactamase CIG75_RS14965 532032acbda5768a019886c2b0a49c23 276 Gene3D G3DSA:1.10.10.10 216 273 5.7E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS14965 532032acbda5768a019886c2b0a49c23 276 Gene3D G3DSA:3.60.15.10 1 215 5.7E-45 T 28-03-2018 IPR001279 Metallo-beta-lactamase CIG75_RS12350 bbd5c599a55f6eb843152c84535ac2c6 413 Gene3D G3DSA:3.40.47.10 262 413 1.2E-52 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS12350 bbd5c599a55f6eb843152c84535ac2c6 413 SMART SM00825 Beta-ketoacyl synthase 5 413 9.4E-16 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CIG75_RS12350 bbd5c599a55f6eb843152c84535ac2c6 413 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3 246 6.2E-62 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CIG75_RS12350 bbd5c599a55f6eb843152c84535ac2c6 413 PIRSF PIRSF000447 1 413 1.8E-189 T 28-03-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 CIG75_RS12350 bbd5c599a55f6eb843152c84535ac2c6 413 SUPERFAMILY SSF53901 214 411 9.72E-74 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS12350 bbd5c599a55f6eb843152c84535ac2c6 413 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 153 169 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CIG75_RS12350 bbd5c599a55f6eb843152c84535ac2c6 413 SUPERFAMILY SSF53901 3 251 2.04E-79 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS12350 bbd5c599a55f6eb843152c84535ac2c6 413 Gene3D G3DSA:3.40.47.10 5 259 9.2E-81 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS12350 bbd5c599a55f6eb843152c84535ac2c6 413 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 3 409 4.3E-200 T 28-03-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 CIG75_RS12350 bbd5c599a55f6eb843152c84535ac2c6 413 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 254 368 7.6E-39 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CIG75_RS20385 effda6bd07eced7086526b6a814d428e 371 Pfam PF12704 MacB-like periplasmic core domain 22 214 1.5E-13 T 28-03-2018 IPR025857 MacB-like periplasmic core domain CIG75_RS20385 effda6bd07eced7086526b6a814d428e 371 Pfam PF02687 FtsX-like permease family 281 362 9.5E-8 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CIG75_RS05330 762a0d0dca7761c9cfe84de35163bbde 459 SUPERFAMILY SSF56112 136 436 7.69E-41 T 28-03-2018 IPR011009 Protein kinase-like domain CIG75_RS05330 762a0d0dca7761c9cfe84de35163bbde 459 Pfam PF01636 Phosphotransferase enzyme family 164 392 9.0E-13 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CIG75_RS05330 762a0d0dca7761c9cfe84de35163bbde 459 Gene3D G3DSA:3.30.200.20 122 218 6.0E-8 T 28-03-2018 CIG75_RS05330 762a0d0dca7761c9cfe84de35163bbde 459 TIGRFAM TIGR02906 spore_CotS: spore coat protein, CotS family 148 425 4.2E-55 T 28-03-2018 IPR014255 Spore coat protein CotS CIG75_RS05330 762a0d0dca7761c9cfe84de35163bbde 459 Gene3D G3DSA:3.90.1200.10 219 450 3.7E-32 T 28-03-2018 CIG75_RS02265 a7142ffe327c0a0ac61a483accebb9a2 219 Pfam PF01895 PhoU domain 122 206 1.1E-21 T 28-03-2018 IPR026022 PhoU domain CIG75_RS02265 a7142ffe327c0a0ac61a483accebb9a2 219 Pfam PF01895 PhoU domain 18 105 3.0E-21 T 28-03-2018 IPR026022 PhoU domain CIG75_RS02265 a7142ffe327c0a0ac61a483accebb9a2 219 Gene3D G3DSA:1.20.58.220 113 219 1.9E-29 T 28-03-2018 CIG75_RS02265 a7142ffe327c0a0ac61a483accebb9a2 219 PIRSF PIRSF003107 1 219 6.1E-74 T 28-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 CIG75_RS02265 a7142ffe327c0a0ac61a483accebb9a2 219 Gene3D G3DSA:1.20.58.220 1 112 3.5E-27 T 28-03-2018 CIG75_RS02265 a7142ffe327c0a0ac61a483accebb9a2 219 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 6 214 8.9E-67 T 28-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 CIG75_RS02265 a7142ffe327c0a0ac61a483accebb9a2 219 SUPERFAMILY SSF109755 5 218 1.26E-69 T 28-03-2018 CIG75_RS05520 bb315655cf2875f5a62a380ca9900530 513 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 373 393 - T 28-03-2018 IPR001110 Uncharacterised protein family UPF0012, conserved site CIG75_RS05520 bb315655cf2875f5a62a380ca9900530 513 Pfam PF00583 Acetyltransferase (GNAT) family 33 152 4.9E-10 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CIG75_RS05520 bb315655cf2875f5a62a380ca9900530 513 SUPERFAMILY SSF56317 226 494 1.26E-57 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CIG75_RS05520 bb315655cf2875f5a62a380ca9900530 513 SUPERFAMILY SSF55729 12 152 1.37E-15 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CIG75_RS05520 bb315655cf2875f5a62a380ca9900530 513 Gene3D G3DSA:3.40.630.30 7 224 2.7E-27 T 28-03-2018 CIG75_RS05520 bb315655cf2875f5a62a380ca9900530 513 Pfam PF00795 Carbon-nitrogen hydrolase 231 490 2.8E-30 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CIG75_RS05520 bb315655cf2875f5a62a380ca9900530 513 Gene3D G3DSA:3.60.110.10 225 511 1.0E-53 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CIG75_RS01955 c54613eee6c6abf12486928efce90966 122 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 4 122 18.62 T 28-03-2018 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 CIG75_RS01955 c54613eee6c6abf12486928efce90966 122 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 27 121 9.5E-37 T 28-03-2018 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CIG75_RS08455 2d7f6b2085c4b922ceba083d0aacd2bc 551 Pfam PF01642 Methylmalonyl-CoA mutase 34 544 4.4E-232 T 28-03-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CIG75_RS08455 2d7f6b2085c4b922ceba083d0aacd2bc 551 Gene3D G3DSA:3.20.20.240 29 546 3.3E-228 T 28-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CIG75_RS08455 2d7f6b2085c4b922ceba083d0aacd2bc 551 SUPERFAMILY SSF51703 6 546 1.75E-216 T 28-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CIG75_RS08455 2d7f6b2085c4b922ceba083d0aacd2bc 551 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 32 547 3.0E-245 T 28-03-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CIG75_RS12585 27e986b31238692ac65bfc4c6562de1b 378 Pfam PF00534 Glycosyl transferases group 1 184 355 1.2E-35 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CIG75_RS12585 27e986b31238692ac65bfc4c6562de1b 378 Pfam PF13439 Glycosyltransferase Family 4 21 168 4.0E-16 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CIG75_RS12585 27e986b31238692ac65bfc4c6562de1b 378 SUPERFAMILY SSF53756 13 375 3.11E-66 T 28-03-2018 CIG75_RS12585 27e986b31238692ac65bfc4c6562de1b 378 Gene3D G3DSA:3.40.50.2000 17 180 9.2E-8 T 28-03-2018 CIG75_RS12585 27e986b31238692ac65bfc4c6562de1b 378 Gene3D G3DSA:3.40.50.2000 181 361 8.9E-43 T 28-03-2018 CIG75_RS14745 764dd6d337560efd536f40bb91b4fad9 78 TIGRFAM TIGR02856 spore_yqfC: sporulation protein YqfC 2 77 2.3E-26 T 28-03-2018 IPR022477 Sporulation protein YqfC CIG75_RS14745 764dd6d337560efd536f40bb91b4fad9 78 Pfam PF07873 YabP family 13 76 5.0E-18 T 28-03-2018 IPR022476 Sporulation protein YabP/YqfC CIG75_RS03720 554500d308347a17f00b0523fb5dbaf0 176 Gene3D G3DSA:2.60.120.10 64 175 1.5E-11 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CIG75_RS03720 554500d308347a17f00b0523fb5dbaf0 176 SMART SM00530 6 61 3.6E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS03720 554500d308347a17f00b0523fb5dbaf0 176 Pfam PF01381 Helix-turn-helix 7 61 1.7E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS03720 554500d308347a17f00b0523fb5dbaf0 176 SUPERFAMILY SSF51182 54 173 5.26E-22 T 28-03-2018 IPR011051 RmlC-like cupin domain CIG75_RS03720 554500d308347a17f00b0523fb5dbaf0 176 Gene3D G3DSA:1.10.260.40 1 63 1.7E-16 T 28-03-2018 CIG75_RS03720 554500d308347a17f00b0523fb5dbaf0 176 SUPERFAMILY SSF47413 1 67 9.65E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CIG75_RS03720 554500d308347a17f00b0523fb5dbaf0 176 Pfam PF07883 Cupin domain 103 169 3.7E-11 T 28-03-2018 IPR013096 Cupin 2, conserved barrel CIG75_RS18725 295f2e35fcdda33231b24b47673a5266 407 Pfam PF01882 Protein of unknown function DUF58 194 276 2.9E-19 T 28-03-2018 IPR002881 Domain of unknown function DUF58 CIG75_RS18725 295f2e35fcdda33231b24b47673a5266 407 Gene3D G3DSA:3.40.50.410 204 358 1.1E-9 T 28-03-2018 IPR002035 von Willebrand factor, type A CIG75_RS17505 c726918830852c00619af4385387c7e9 773 Pfam PF03176 MMPL family 502 734 1.1E-32 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CIG75_RS17505 c726918830852c00619af4385387c7e9 773 Pfam PF03176 MMPL family 45 394 4.9E-49 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CIG75_RS17505 c726918830852c00619af4385387c7e9 773 Gene3D G3DSA:1.20.1640.10 166 380 3.1E-28 T 28-03-2018 CIG75_RS17505 c726918830852c00619af4385387c7e9 773 SUPERFAMILY SSF82866 186 369 1.57E-25 T 28-03-2018 CIG75_RS17505 c726918830852c00619af4385387c7e9 773 Gene3D G3DSA:1.20.1640.10 510 732 5.7E-28 T 28-03-2018 CIG75_RS17505 c726918830852c00619af4385387c7e9 773 SUPERFAMILY SSF82866 518 734 4.58E-26 T 28-03-2018 CIG75_RS05380 b49f7535f101bc270a6491f8ce48b85a 692 Gene3D G3DSA:1.20.120.570 308 470 5.9E-17 T 28-03-2018 CIG75_RS05380 b49f7535f101bc270a6491f8ce48b85a 692 Gene3D G3DSA:3.40.1710.10 46 213 8.7E-23 T 28-03-2018 CIG75_RS05380 b49f7535f101bc270a6491f8ce48b85a 692 Pfam PF12698 ABC-2 family transporter protein 399 669 1.3E-19 T 28-03-2018 CIG75_RS05380 b49f7535f101bc270a6491f8ce48b85a 692 TIGRFAM TIGR03062 pip_yhgE_Cterm: YhgE/Pip C-terminal domain 473 678 2.9E-63 T 28-03-2018 IPR017501 Phage infection protein, YhgE, C-terminal CIG75_RS05380 b49f7535f101bc270a6491f8ce48b85a 692 TIGRFAM TIGR03061 pip_yhgE_Nterm: YhgE/Pip N-terminal domain 10 164 4.8E-46 T 28-03-2018 IPR017500 Phage infection protein, YhgE, N-terminal CIG75_RS05380 b49f7535f101bc270a6491f8ce48b85a 692 SUPERFAMILY SSF58104 335 445 6.02E-5 T 28-03-2018 CIG75_RS05380 b49f7535f101bc270a6491f8ce48b85a 692 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 171 194 2.5E-4 T 28-03-2018 IPR023908 xxxLxxG heptad repeat CIG75_RS05380 b49f7535f101bc270a6491f8ce48b85a 692 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 379 406 3.3E-4 T 28-03-2018 IPR023908 xxxLxxG heptad repeat CIG75_RS05380 b49f7535f101bc270a6491f8ce48b85a 692 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 231 257 3.3E-5 T 28-03-2018 IPR023908 xxxLxxG heptad repeat CIG75_RS13305 6a30959d19617f9fd338d774a23ae631 304 Pfam PF00550 Phosphopantetheine attachment site 236 300 1.2E-6 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS13305 6a30959d19617f9fd338d774a23ae631 304 PRINTS PR01398 Isochorismatase signature 168 186 2.9E-44 T 28-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CIG75_RS13305 6a30959d19617f9fd338d774a23ae631 304 PRINTS PR01398 Isochorismatase signature 80 99 2.9E-44 T 28-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CIG75_RS13305 6a30959d19617f9fd338d774a23ae631 304 PRINTS PR01398 Isochorismatase signature 186 203 2.9E-44 T 28-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CIG75_RS13305 6a30959d19617f9fd338d774a23ae631 304 PRINTS PR01398 Isochorismatase signature 2 14 2.9E-44 T 28-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CIG75_RS13305 6a30959d19617f9fd338d774a23ae631 304 PRINTS PR01398 Isochorismatase signature 63 80 2.9E-44 T 28-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CIG75_RS13305 6a30959d19617f9fd338d774a23ae631 304 PRINTS PR01398 Isochorismatase signature 112 134 2.9E-44 T 28-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CIG75_RS13305 6a30959d19617f9fd338d774a23ae631 304 Gene3D G3DSA:1.10.1200.10 212 304 3.0E-11 T 28-03-2018 CIG75_RS13305 6a30959d19617f9fd338d774a23ae631 304 Pfam PF00857 Isochorismatase family 32 205 1.5E-36 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CIG75_RS13305 6a30959d19617f9fd338d774a23ae631 304 SUPERFAMILY SSF52499 1 211 3.4E-58 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CIG75_RS13305 6a30959d19617f9fd338d774a23ae631 304 Gene3D G3DSA:3.40.50.850 1 211 4.5E-45 T 28-03-2018 CIG75_RS13305 6a30959d19617f9fd338d774a23ae631 304 PIRSF PIRSF001111 1 304 6.6E-127 T 28-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CIG75_RS13305 6a30959d19617f9fd338d774a23ae631 304 SUPERFAMILY SSF47336 234 303 9.55E-10 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS17230 ed2fe28be0e94c0f2aa54085032fabed 360 Pfam PF03845 Spore germination protein 6 309 5.0E-28 T 28-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 CIG75_RS01520 f4f8601b9a3d17b5fc999287987b62b8 76 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 22 31 - T 28-03-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 CIG75_RS01520 f4f8601b9a3d17b5fc999287987b62b8 76 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 12 58 4.9E-10 T 28-03-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 CIG75_RS20415 ff76f2f552cd5e57981cbf0066d1a86b 527 Gene3D G3DSA:3.40.50.1820 51 345 6.3E-14 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS20415 ff76f2f552cd5e57981cbf0066d1a86b 527 Gene3D G3DSA:2.60.40.10 412 516 6.7E-7 T 28-03-2018 IPR013783 Immunoglobulin-like fold CIG75_RS20415 ff76f2f552cd5e57981cbf0066d1a86b 527 SUPERFAMILY SSF53474 55 259 1.84E-17 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS19705 ac0d5833f13d3f7b5f9b4eadb498ce65 223 SMART SM00322 60 125 3.0E-7 T 28-03-2018 IPR004087 K Homology domain GO:0003676 CIG75_RS19705 ac0d5833f13d3f7b5f9b4eadb498ce65 223 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 209 1.2E-98 T 28-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 CIG75_RS19705 ac0d5833f13d3f7b5f9b4eadb498ce65 223 SUPERFAMILY SSF54821 107 206 1.7E-40 T 28-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CIG75_RS19705 ac0d5833f13d3f7b5f9b4eadb498ce65 223 SUPERFAMILY SSF54814 2 106 8.37E-40 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CIG75_RS19705 ac0d5833f13d3f7b5f9b4eadb498ce65 223 Pfam PF00189 Ribosomal protein S3, C-terminal domain 120 202 5.2E-41 T 28-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CIG75_RS19705 ac0d5833f13d3f7b5f9b4eadb498ce65 223 Gene3D G3DSA:3.30.300.20 17 107 3.3E-33 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CIG75_RS19705 ac0d5833f13d3f7b5f9b4eadb498ce65 223 Pfam PF07650 KH domain 38 110 1.1E-19 T 28-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CIG75_RS19705 ac0d5833f13d3f7b5f9b4eadb498ce65 223 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 206 39.194 T 28-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 CIG75_RS19705 ac0d5833f13d3f7b5f9b4eadb498ce65 223 ProSitePatterns PS00548 Ribosomal protein S3 signature. 163 197 - T 28-03-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CIG75_RS19705 ac0d5833f13d3f7b5f9b4eadb498ce65 223 Gene3D G3DSA:3.30.1140.32 108 208 3.4E-38 T 28-03-2018 CIG75_RS02970 dbc3d01b00874054400a9dcefc54fdfd 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 221 1.4E-22 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CIG75_RS02970 dbc3d01b00874054400a9dcefc54fdfd 226 SMART SM00862 145 221 3.9E-26 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CIG75_RS02970 dbc3d01b00874054400a9dcefc54fdfd 226 SMART SM00448 3 113 2.5E-41 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CIG75_RS02970 dbc3d01b00874054400a9dcefc54fdfd 226 SUPERFAMILY SSF52172 4 174 6.88E-42 T 28-03-2018 IPR011006 CheY-like superfamily CIG75_RS02970 dbc3d01b00874054400a9dcefc54fdfd 226 Gene3D G3DSA:1.10.10.10 124 226 1.1E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS02970 dbc3d01b00874054400a9dcefc54fdfd 226 Pfam PF00072 Response regulator receiver domain 5 113 2.6E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CIG75_RS02970 dbc3d01b00874054400a9dcefc54fdfd 226 Gene3D G3DSA:3.40.50.2300 2 123 1.2E-37 T 28-03-2018 CIG75_RS19540 586a130960d27b90a3328355cb30d5a8 248 Gene3D G3DSA:3.20.20.370 42 247 3.2E-51 T 28-03-2018 CIG75_RS19540 586a130960d27b90a3328355cb30d5a8 248 SUPERFAMILY SSF88713 40 238 2.89E-57 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CIG75_RS19540 586a130960d27b90a3328355cb30d5a8 248 Pfam PF01522 Polysaccharide deacetylase 48 170 8.5E-27 T 28-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CIG75_RS06555 423871bd8ff6769cd0b9a943048cc4da 1515 Pfam PF00550 Phosphopantetheine attachment site 1415 1479 3.4E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS06555 423871bd8ff6769cd0b9a943048cc4da 1515 SMART SM00823 Phosphopantetheine attachment site 1414 1483 3.8E-7 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS06555 423871bd8ff6769cd0b9a943048cc4da 1515 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2 252 7.5E-75 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CIG75_RS06555 423871bd8ff6769cd0b9a943048cc4da 1515 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 531 830 2.6E-107 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CIG75_RS06555 423871bd8ff6769cd0b9a943048cc4da 1515 SMART SM00825 Beta-ketoacyl synthase 4 430 9.9E-194 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CIG75_RS06555 423871bd8ff6769cd0b9a943048cc4da 1515 Gene3D G3DSA:3.40.366.10 527 673 1.0E-44 T 28-03-2018 CIG75_RS06555 423871bd8ff6769cd0b9a943048cc4da 1515 Pfam PF00698 Acyl transferase domain 529 829 1.4E-57 T 28-03-2018 IPR014043 Acyl transferase CIG75_RS06555 423871bd8ff6769cd0b9a943048cc4da 1515 Gene3D G3DSA:3.40.50.720 927 1097 1.7E-7 T 28-03-2018 CIG75_RS06555 423871bd8ff6769cd0b9a943048cc4da 1515 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1146 1326 3.3E-13 T 28-03-2018 CIG75_RS06555 423871bd8ff6769cd0b9a943048cc4da 1515 Gene3D G3DSA:3.40.47.10 267 428 5.8E-59 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS06555 423871bd8ff6769cd0b9a943048cc4da 1515 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 382 493 5.8E-20 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS06555 423871bd8ff6769cd0b9a943048cc4da 1515 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 165 181 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CIG75_RS06555 423871bd8ff6769cd0b9a943048cc4da 1515 SUPERFAMILY SSF52151 528 661 1.23E-67 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CIG75_RS06555 423871bd8ff6769cd0b9a943048cc4da 1515 SUPERFAMILY SSF52151 721 817 1.23E-67 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CIG75_RS06555 423871bd8ff6769cd0b9a943048cc4da 1515 SUPERFAMILY SSF51735 900 1130 6.53E-27 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS06555 423871bd8ff6769cd0b9a943048cc4da 1515 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1438 1453 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS06555 423871bd8ff6769cd0b9a943048cc4da 1515 SUPERFAMILY SSF55048 659 719 3.66E-10 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CIG75_RS06555 423871bd8ff6769cd0b9a943048cc4da 1515 SUPERFAMILY SSF51735 1144 1374 2.07E-20 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS06555 423871bd8ff6769cd0b9a943048cc4da 1515 SUPERFAMILY SSF47336 1406 1480 1.7E-19 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS06555 423871bd8ff6769cd0b9a943048cc4da 1515 Gene3D G3DSA:3.40.47.10 1 263 1.1E-72 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS06555 423871bd8ff6769cd0b9a943048cc4da 1515 Pfam PF08659 KR domain 1146 1319 2.2E-30 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS06555 423871bd8ff6769cd0b9a943048cc4da 1515 Gene3D G3DSA:1.10.1200.10 1398 1492 5.1E-23 T 28-03-2018 CIG75_RS06555 423871bd8ff6769cd0b9a943048cc4da 1515 SUPERFAMILY SSF53901 405 426 2.88E-85 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS06555 423871bd8ff6769cd0b9a943048cc4da 1515 SUPERFAMILY SSF53901 148 374 2.88E-85 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS06555 423871bd8ff6769cd0b9a943048cc4da 1515 SUPERFAMILY SSF53901 2 118 2.88E-85 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS06555 423871bd8ff6769cd0b9a943048cc4da 1515 Gene3D G3DSA:3.40.50.720 1138 1396 1.1E-28 T 28-03-2018 CIG75_RS06555 423871bd8ff6769cd0b9a943048cc4da 1515 Gene3D G3DSA:3.30.70.250 674 716 8.5E-18 T 28-03-2018 CIG75_RS06555 423871bd8ff6769cd0b9a943048cc4da 1515 Gene3D G3DSA:3.40.366.10 717 837 1.5E-25 T 28-03-2018 CIG75_RS06555 423871bd8ff6769cd0b9a943048cc4da 1515 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 260 379 7.3E-43 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CIG75_RS15920 59b42a3387ec5efc33ce4f5a11700ecb 129 Gene3D G3DSA:3.30.479.10 1 122 3.0E-40 T 28-03-2018 CIG75_RS15920 59b42a3387ec5efc33ce4f5a11700ecb 129 PIRSF PIRSF006113 1 123 6.8E-24 T 28-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 CIG75_RS15920 59b42a3387ec5efc33ce4f5a11700ecb 129 TIGRFAM TIGR03367 queuosine_QueD: queuosine biosynthesis protein QueD 3 91 4.7E-31 T 28-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 CIG75_RS15920 59b42a3387ec5efc33ce4f5a11700ecb 129 SUPERFAMILY SSF55620 3 122 1.95E-38 T 28-03-2018 CIG75_RS15920 59b42a3387ec5efc33ce4f5a11700ecb 129 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 3 122 6.5E-37 T 28-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 CIG75_RS17885 6e9d0c1a67799162e295ba368a657dd0 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 196 3.6E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CIG75_RS17885 6e9d0c1a67799162e295ba368a657dd0 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 168 3.6E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CIG75_RS17885 6e9d0c1a67799162e295ba368a657dd0 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 184 3.6E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CIG75_RS17885 6e9d0c1a67799162e295ba368a657dd0 221 SMART SM00448 5 118 7.5E-32 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CIG75_RS17885 6e9d0c1a67799162e295ba368a657dd0 221 SMART SM00421 151 208 1.1E-28 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CIG75_RS17885 6e9d0c1a67799162e295ba368a657dd0 221 Pfam PF00196 Bacterial regulatory proteins, luxR family 153 208 2.6E-21 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CIG75_RS17885 6e9d0c1a67799162e295ba368a657dd0 221 SUPERFAMILY SSF46894 141 215 5.44E-24 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CIG75_RS17885 6e9d0c1a67799162e295ba368a657dd0 221 ProSitePatterns PS00622 LuxR-type HTH domain signature. 168 195 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CIG75_RS17885 6e9d0c1a67799162e295ba368a657dd0 221 SUPERFAMILY SSF52172 4 133 1.42E-33 T 28-03-2018 IPR011006 CheY-like superfamily CIG75_RS17885 6e9d0c1a67799162e295ba368a657dd0 221 Gene3D G3DSA:1.10.10.10 137 213 2.2E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS17885 6e9d0c1a67799162e295ba368a657dd0 221 Gene3D G3DSA:3.40.50.2300 4 136 1.0E-39 T 28-03-2018 CIG75_RS17885 6e9d0c1a67799162e295ba368a657dd0 221 Pfam PF00072 Response regulator receiver domain 7 118 1.0E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CIG75_RS04685 a01c75027198b855b21cc68f3ba6d61d 384 Gene3D G3DSA:1.10.10.60 283 352 1.3E-7 T 28-03-2018 CIG75_RS04685 a01c75027198b855b21cc68f3ba6d61d 384 Pfam PF13556 PucR C-terminal helix-turn-helix domain 316 373 9.1E-22 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain CIG75_RS15430 921e706b9c1cbc0fd32b67275e21086f 142 Gene3D G3DSA:2.60.120.380 27 138 1.3E-10 T 28-03-2018 CIG75_RS02195 dacbbf9e7dc5c0038df8b20bde101782 310 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 93 235 4.1E-43 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CIG75_RS02195 dacbbf9e7dc5c0038df8b20bde101782 310 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 93 235 1.9E-46 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CIG75_RS07350 43522c2a876edaf02a447a400a9326e2 101 SUPERFAMILY SSF54292 6 98 8.17E-20 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CIG75_RS07350 43522c2a876edaf02a447a400a9326e2 101 Gene3D G3DSA:3.10.20.30 1 101 5.0E-20 T 28-03-2018 IPR012675 Beta-grasp domain CIG75_RS07350 43522c2a876edaf02a447a400a9326e2 101 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 43 51 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CIG75_RS07350 43522c2a876edaf02a447a400a9326e2 101 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 15 87 8.3E-10 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CIG75_RS05740 f4ac26660db6eb8b8a039c6dccb4425a 555 Gene3D G3DSA:3.40.50.10320 147 471 2.7E-37 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CIG75_RS05740 f4ac26660db6eb8b8a039c6dccb4425a 555 SUPERFAMILY SSF102588 148 393 1.19E-35 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CIG75_RS05740 f4ac26660db6eb8b8a039c6dccb4425a 555 Pfam PF02585 GlcNAc-PI de-N-acetylase 152 321 1.0E-23 T 28-03-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 CIG75_RS09745 76a5cc9ac4e2e1a8155f614b36c0917f 152 PIRSF PIRSF037663 1 149 1.3E-65 T 28-03-2018 IPR017255 Acetyltransferase, GNAT, predicted CIG75_RS09745 76a5cc9ac4e2e1a8155f614b36c0917f 152 Gene3D G3DSA:3.40.630.30 1 148 9.8E-29 T 28-03-2018 CIG75_RS09745 76a5cc9ac4e2e1a8155f614b36c0917f 152 SUPERFAMILY SSF55729 1 145 2.62E-27 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CIG75_RS09745 76a5cc9ac4e2e1a8155f614b36c0917f 152 Pfam PF00583 Acetyltransferase (GNAT) family 32 124 1.9E-18 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CIG75_RS05320 b3d6b77c9285bcc33a40ecab2f9f3956 384 Gene3D G3DSA:3.30.70.20 39 198 0.0044 T 28-03-2018 CIG75_RS05320 b3d6b77c9285bcc33a40ecab2f9f3956 384 Pfam PF13484 4Fe-4S double cluster binding domain 189 253 1.2E-11 T 28-03-2018 CIG75_RS05320 b3d6b77c9285bcc33a40ecab2f9f3956 384 SUPERFAMILY SSF54862 189 287 3.14E-9 T 28-03-2018 CIG75_RS05320 b3d6b77c9285bcc33a40ecab2f9f3956 384 Gene3D G3DSA:1.25.40.70 272 379 1.8E-10 T 28-03-2018 CIG75_RS05320 b3d6b77c9285bcc33a40ecab2f9f3956 384 SMART SM00567 E-Z type HEAT repeats 333 362 68.0 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CIG75_RS05320 b3d6b77c9285bcc33a40ecab2f9f3956 384 SMART SM00567 E-Z type HEAT repeats 301 330 10.0 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CIG75_RS05320 b3d6b77c9285bcc33a40ecab2f9f3956 384 Pfam PF08331 Domain of unknown function (DUF1730) 58 131 5.9E-19 T 28-03-2018 IPR013542 Domain of unknown function DUF1730 MetaCyc: PWY-6700 CIG75_RS05320 b3d6b77c9285bcc33a40ecab2f9f3956 384 SUPERFAMILY SSF48371 302 374 1.25E-8 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 CIG75_RS05320 b3d6b77c9285bcc33a40ecab2f9f3956 384 Pfam PF13646 HEAT repeats 303 375 2.3E-12 T 28-03-2018 CIG75_RS05320 b3d6b77c9285bcc33a40ecab2f9f3956 384 TIGRFAM TIGR00276 TIGR00276: epoxyqueuosine reductase 11 345 6.4E-109 T 28-03-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 CIG75_RS05320 b3d6b77c9285bcc33a40ecab2f9f3956 384 Gene3D G3DSA:3.30.70.20 199 271 3.1E-6 T 28-03-2018 CIG75_RS06820 9869608099d6828a5cb97a1593ae1d56 471 TIGRFAM TIGR00474 selA: L-seryl-tRNA(Sec) selenium transferase 11 464 4.6E-182 T 28-03-2018 IPR004534 L-seryl-tRNA(Sec) selenium transferase GO:0001514|GO:0004125|GO:0005737 KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 CIG75_RS06820 9869608099d6828a5cb97a1593ae1d56 471 SUPERFAMILY SSF53383 78 469 1.93E-48 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CIG75_RS06820 9869608099d6828a5cb97a1593ae1d56 471 Gene3D G3DSA:3.40.640.10 98 357 1.2E-33 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CIG75_RS06820 9869608099d6828a5cb97a1593ae1d56 471 Hamap MF_00423 L-seryl-tRNA(Sec) selenium transferase [selA]. 1 469 204.648 T 28-03-2018 IPR004534 L-seryl-tRNA(Sec) selenium transferase GO:0001514|GO:0004125|GO:0005737 KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 CIG75_RS06820 9869608099d6828a5cb97a1593ae1d56 471 Pfam PF03841 L-seryl-tRNA selenium transferase 86 451 1.6E-157 T 28-03-2018 IPR018319 L-seryl-tRNA selenium transferase-like KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 CIG75_RS17740 9be27b91832c0840bb72fa7b209a031b 121 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 3 116 17.136 T 28-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CIG75_RS17740 9be27b91832c0840bb72fa7b209a031b 121 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 5 110 7.9E-21 T 28-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CIG75_RS10375 9d35f6c9c4f8b60382ef1420e4c3f97d 172 SUPERFAMILY SSF51182 54 169 1.29E-20 T 28-03-2018 IPR011051 RmlC-like cupin domain CIG75_RS10375 9d35f6c9c4f8b60382ef1420e4c3f97d 172 SMART SM00530 6 61 3.2E-12 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS10375 9d35f6c9c4f8b60382ef1420e4c3f97d 172 SUPERFAMILY SSF47413 2 67 8.31E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CIG75_RS10375 9d35f6c9c4f8b60382ef1420e4c3f97d 172 Pfam PF01381 Helix-turn-helix 7 61 2.3E-12 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS10375 9d35f6c9c4f8b60382ef1420e4c3f97d 172 Gene3D G3DSA:2.60.120.10 42 171 6.7E-21 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CIG75_RS10375 9d35f6c9c4f8b60382ef1420e4c3f97d 172 Gene3D G3DSA:1.10.260.40 1 41 6.8E-11 T 28-03-2018 CIG75_RS10375 9d35f6c9c4f8b60382ef1420e4c3f97d 172 Pfam PF07883 Cupin domain 100 166 3.8E-14 T 28-03-2018 IPR013096 Cupin 2, conserved barrel CIG75_RS17710 11a8d9d64892f202f8401062aaa5fd97 429 Gene3D G3DSA:1.25.40.10 242 283 2.0E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS17710 11a8d9d64892f202f8401062aaa5fd97 429 SUPERFAMILY SSF48452 142 350 1.9E-25 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS17710 11a8d9d64892f202f8401062aaa5fd97 429 Gene3D G3DSA:1.10.260.40 2 70 1.1E-15 T 28-03-2018 CIG75_RS17710 11a8d9d64892f202f8401062aaa5fd97 429 Pfam PF13424 Tetratricopeptide repeat 111 168 3.8E-8 T 28-03-2018 CIG75_RS17710 11a8d9d64892f202f8401062aaa5fd97 429 Pfam PF13181 Tetratricopeptide repeat 231 259 0.0031 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS17710 11a8d9d64892f202f8401062aaa5fd97 429 Pfam PF13181 Tetratricopeptide repeat 191 219 0.0034 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS17710 11a8d9d64892f202f8401062aaa5fd97 429 Gene3D G3DSA:1.25.40.10 71 139 4.3E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS17710 11a8d9d64892f202f8401062aaa5fd97 429 Gene3D G3DSA:1.25.40.10 202 241 3.8E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS17710 11a8d9d64892f202f8401062aaa5fd97 429 Pfam PF13432 Tetratricopeptide repeat 280 341 0.0097 T 28-03-2018 CIG75_RS17710 11a8d9d64892f202f8401062aaa5fd97 429 SUPERFAMILY SSF47413 3 62 2.42E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CIG75_RS17710 11a8d9d64892f202f8401062aaa5fd97 429 Pfam PF01381 Helix-turn-helix 8 61 5.9E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS17710 11a8d9d64892f202f8401062aaa5fd97 429 SUPERFAMILY SSF48452 74 177 1.25E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS17710 11a8d9d64892f202f8401062aaa5fd97 429 SMART SM00530 7 61 5.7E-15 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS17710 11a8d9d64892f202f8401062aaa5fd97 429 SMART SM00028 108 141 66.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS17710 11a8d9d64892f202f8401062aaa5fd97 429 SMART SM00028 190 223 12.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS17710 11a8d9d64892f202f8401062aaa5fd97 429 SMART SM00028 148 181 15.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS17710 11a8d9d64892f202f8401062aaa5fd97 429 SMART SM00028 310 343 0.71 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS17710 11a8d9d64892f202f8401062aaa5fd97 429 SMART SM00028 230 263 5.1 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS17710 11a8d9d64892f202f8401062aaa5fd97 429 Gene3D G3DSA:1.25.40.10 284 426 5.5E-17 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS17710 11a8d9d64892f202f8401062aaa5fd97 429 Gene3D G3DSA:1.10.150.160 140 201 6.6E-8 T 28-03-2018 CIG75_RS02520 0e9fb4d5268791998e8f5ff64810faec 450 Gene3D G3DSA:3.40.120.10 168 264 9.2E-26 T 28-03-2018 CIG75_RS02520 0e9fb4d5268791998e8f5ff64810faec 450 SUPERFAMILY SSF53738 161 258 3.1E-26 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CIG75_RS02520 0e9fb4d5268791998e8f5ff64810faec 450 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 95 109 7.3E-13 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CIG75_RS02520 0e9fb4d5268791998e8f5ff64810faec 450 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 175 194 7.3E-13 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CIG75_RS02520 0e9fb4d5268791998e8f5ff64810faec 450 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 235 250 7.3E-13 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CIG75_RS02520 0e9fb4d5268791998e8f5ff64810faec 450 SUPERFAMILY SSF53738 3 182 1.77E-47 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CIG75_RS02520 0e9fb4d5268791998e8f5ff64810faec 450 SUPERFAMILY SSF53738 259 365 4.71E-31 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CIG75_RS02520 0e9fb4d5268791998e8f5ff64810faec 450 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 96 105 - T 28-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CIG75_RS02520 0e9fb4d5268791998e8f5ff64810faec 450 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 1 446 44.996 T 28-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CIG75_RS02520 0e9fb4d5268791998e8f5ff64810faec 450 Gene3D G3DSA:3.30.310.50 376 447 7.2E-23 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CIG75_RS02520 0e9fb4d5268791998e8f5ff64810faec 450 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 169 255 1.1E-16 T 28-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CIG75_RS02520 0e9fb4d5268791998e8f5ff64810faec 450 Gene3D G3DSA:3.40.120.10 265 375 2.2E-32 T 28-03-2018 CIG75_RS02520 0e9fb4d5268791998e8f5ff64810faec 450 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 134 2.3E-42 T 28-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CIG75_RS02520 0e9fb4d5268791998e8f5ff64810faec 450 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 259 369 1.1E-31 T 28-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CIG75_RS02520 0e9fb4d5268791998e8f5ff64810faec 450 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 5 444 2.2E-181 T 28-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CIG75_RS02520 0e9fb4d5268791998e8f5ff64810faec 450 SUPERFAMILY SSF55957 360 447 1.07E-25 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CIG75_RS02520 0e9fb4d5268791998e8f5ff64810faec 450 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 375 443 3.9E-19 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CIG75_RS02520 0e9fb4d5268791998e8f5ff64810faec 450 Gene3D G3DSA:3.40.120.10 2 167 1.1E-44 T 28-03-2018 CIG75_RS03055 65acc98e9ff01e2e0bfd27379f103d45 481 SMART SM00155 394 421 2.0E-5 T 28-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CIG75_RS03055 65acc98e9ff01e2e0bfd27379f103d45 481 SMART SM00155 217 244 1.9E-5 T 28-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CIG75_RS03055 65acc98e9ff01e2e0bfd27379f103d45 481 Pfam PF13396 Phospholipase_D-nuclease N-terminal 19 62 2.0E-9 T 28-03-2018 IPR027379 Cardiolipin synthase N-terminal CIG75_RS03055 65acc98e9ff01e2e0bfd27379f103d45 481 Hamap MF_01916 Cardiolipin synthase. 15 481 42.156 T 28-03-2018 IPR030874 Cardiolipin synthase, Firmicutes-type GO:0008808|GO:0032049 CIG75_RS03055 65acc98e9ff01e2e0bfd27379f103d45 481 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 13 481 2.7E-166 T 28-03-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 CIG75_RS03055 65acc98e9ff01e2e0bfd27379f103d45 481 Gene3D G3DSA:3.30.870.10 311 471 5.8E-32 T 28-03-2018 CIG75_RS03055 65acc98e9ff01e2e0bfd27379f103d45 481 Pfam PF13091 PLD-like domain 322 448 2.0E-27 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CIG75_RS03055 65acc98e9ff01e2e0bfd27379f103d45 481 Pfam PF13091 PLD-like domain 137 261 1.0E-12 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CIG75_RS03055 65acc98e9ff01e2e0bfd27379f103d45 481 SUPERFAMILY SSF56024 269 465 2.47E-51 T 28-03-2018 CIG75_RS03055 65acc98e9ff01e2e0bfd27379f103d45 481 Gene3D G3DSA:3.30.870.10 108 310 6.5E-35 T 28-03-2018 CIG75_RS03055 65acc98e9ff01e2e0bfd27379f103d45 481 SUPERFAMILY SSF56024 101 310 2.23E-53 T 28-03-2018 CIG75_RS01535 90c80a5656f1237a5811336a0cb03ee1 346 Gene3D G3DSA:3.40.50.720 194 314 6.7E-14 T 28-03-2018 CIG75_RS01535 90c80a5656f1237a5811336a0cb03ee1 346 Pfam PF00107 Zinc-binding dehydrogenase 200 295 1.1E-7 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CIG75_RS01535 90c80a5656f1237a5811336a0cb03ee1 346 SUPERFAMILY SSF51735 182 310 1.01E-16 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS01535 90c80a5656f1237a5811336a0cb03ee1 346 Gene3D G3DSA:3.90.180.10 17 193 1.0E-8 T 28-03-2018 CIG75_RS02380 01903b15d0eabde668085ca04d5459c1 281 PRINTS PR00207 Flagellin signature 35 52 2.3E-25 T 28-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 CIG75_RS02380 01903b15d0eabde668085ca04d5459c1 281 PRINTS PR00207 Flagellin signature 74 93 2.3E-25 T 28-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 CIG75_RS02380 01903b15d0eabde668085ca04d5459c1 281 PRINTS PR00207 Flagellin signature 109 132 2.3E-25 T 28-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 CIG75_RS02380 01903b15d0eabde668085ca04d5459c1 281 Gene3D G3DSA:1.20.1330.10 38 253 7.1E-79 T 28-03-2018 CIG75_RS02380 01903b15d0eabde668085ca04d5459c1 281 Pfam PF00700 Bacterial flagellin C-terminal helical region 195 280 5.0E-32 T 28-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 CIG75_RS02380 01903b15d0eabde668085ca04d5459c1 281 SUPERFAMILY SSF64518 1 281 3.92E-97 T 28-03-2018 CIG75_RS02380 01903b15d0eabde668085ca04d5459c1 281 Pfam PF00669 Bacterial flagellin N-terminal helical region 3 139 2.6E-44 T 28-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 CIG75_RS09595 2686e1eaafe70a398b7c3149a14adfe0 256 Gene3D G3DSA:3.20.20.370 25 248 1.5E-67 T 28-03-2018 CIG75_RS09595 2686e1eaafe70a398b7c3149a14adfe0 256 Pfam PF01522 Polysaccharide deacetylase 51 171 7.4E-38 T 28-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CIG75_RS09595 2686e1eaafe70a398b7c3149a14adfe0 256 SUPERFAMILY SSF88713 42 244 8.7E-72 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CIG75_RS11210 94efa43f80da3a48842a4636c3ce2eea 133 Pfam PF04965 Gene 25-like lysozyme 27 117 8.0E-24 T 28-03-2018 IPR007048 GpW/Gp25/anti-adapter protein IraD CIG75_RS11210 94efa43f80da3a48842a4636c3ce2eea 133 Gene3D G3DSA:3.10.450.40 1 132 5.4E-39 T 28-03-2018 CIG75_RS11210 94efa43f80da3a48842a4636c3ce2eea 133 SUPERFAMILY SSF160719 23 131 5.1E-33 T 28-03-2018 CIG75_RS07060 047f4f891110e01f20ba63030e941072 203 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 66 1.4E-10 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CIG75_RS07060 047f4f891110e01f20ba63030e941072 203 Gene3D G3DSA:3.40.50.620 1 200 1.9E-55 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CIG75_RS07060 047f4f891110e01f20ba63030e941072 203 SUPERFAMILY SSF52374 2 198 1.94E-52 T 28-03-2018 CIG75_RS07060 047f4f891110e01f20ba63030e941072 203 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 1 199 31.281 T 28-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 CIG75_RS07060 047f4f891110e01f20ba63030e941072 203 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 5 198 1.6E-55 T 28-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 CIG75_RS07060 047f4f891110e01f20ba63030e941072 203 Pfam PF01467 Cytidylyltransferase-like 5 173 2.8E-28 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CIG75_RS15970 f19306f350fcb583971489f361c7925c 439 Gene3D G3DSA:1.20.1250.20 26 226 7.6E-20 T 28-03-2018 CIG75_RS15970 f19306f350fcb583971489f361c7925c 439 SUPERFAMILY SSF103473 33 425 3.79E-42 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS15970 f19306f350fcb583971489f361c7925c 439 Pfam PF05977 Transmembrane secretion effector 30 299 2.9E-18 T 28-03-2018 IPR010290 Transmembrane secretion effector CIG75_RS15970 f19306f350fcb583971489f361c7925c 439 Gene3D G3DSA:1.20.1250.20 236 438 7.8E-19 T 28-03-2018 CIG75_RS15970 f19306f350fcb583971489f361c7925c 439 PRINTS PR01988 Putative bacilysin exporter bacE signature 166 187 5.2E-11 T 28-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CIG75_RS15970 f19306f350fcb583971489f361c7925c 439 PRINTS PR01988 Putative bacilysin exporter bacE signature 102 120 5.2E-11 T 28-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CIG75_RS15970 f19306f350fcb583971489f361c7925c 439 PRINTS PR01988 Putative bacilysin exporter bacE signature 39 61 5.2E-11 T 28-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CIG75_RS15970 f19306f350fcb583971489f361c7925c 439 PRINTS PR01988 Putative bacilysin exporter bacE signature 193 210 5.2E-11 T 28-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CIG75_RS15970 f19306f350fcb583971489f361c7925c 439 PRINTS PR01988 Putative bacilysin exporter bacE signature 398 421 5.2E-11 T 28-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CIG75_RS14590 f349fc7c8dc91462635a1c919117223a 614 PIRSF PIRSF001589 1 611 5.2E-137 T 28-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 CIG75_RS14590 f349fc7c8dc91462635a1c919117223a 614 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 533 4.5E-160 T 28-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 CIG75_RS14590 f349fc7c8dc91462635a1c919117223a 614 Pfam PF13537 Glutamine amidotransferase domain 48 168 1.3E-43 T 28-03-2018 IPR017932 Glutamine amidotransferase type 2 domain CIG75_RS14590 f349fc7c8dc91462635a1c919117223a 614 Pfam PF00733 Asparagine synthase 242 606 3.6E-95 T 28-03-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 CIG75_RS14590 f349fc7c8dc91462635a1c919117223a 614 Gene3D G3DSA:3.60.20.10 1 223 8.2E-56 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CIG75_RS14590 f349fc7c8dc91462635a1c919117223a 614 SUPERFAMILY SSF52402 453 572 2.33E-68 T 28-03-2018 CIG75_RS14590 f349fc7c8dc91462635a1c919117223a 614 SUPERFAMILY SSF52402 230 395 2.33E-68 T 28-03-2018 CIG75_RS14590 f349fc7c8dc91462635a1c919117223a 614 SUPERFAMILY SSF56235 1 226 1.2E-63 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CIG75_RS14590 f349fc7c8dc91462635a1c919117223a 614 Gene3D G3DSA:3.40.50.620 224 613 2.5E-65 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CIG75_RS07835 72203b1922265f7df1d988aceeb727fa 434 Gene3D G3DSA:3.30.70.1050 4 122 1.8E-32 T 28-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 CIG75_RS07835 72203b1922265f7df1d988aceeb727fa 434 SUPERFAMILY SSF109998 254 434 1.96E-43 T 28-03-2018 IPR027304 Trigger factor/SurA domain CIG75_RS07835 72203b1922265f7df1d988aceeb727fa 434 SUPERFAMILY SSF54534 92 245 1.02E-33 T 28-03-2018 CIG75_RS07835 72203b1922265f7df1d988aceeb727fa 434 TIGRFAM TIGR00115 tig: trigger factor 17 427 3.7E-138 T 28-03-2018 IPR005215 Trigger factor GO:0015031 CIG75_RS07835 72203b1922265f7df1d988aceeb727fa 434 Gene3D G3DSA:1.10.3120.10 217 402 3.3E-50 T 28-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 CIG75_RS07835 72203b1922265f7df1d988aceeb727fa 434 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 164 243 4.1E-14 T 28-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain CIG75_RS07835 72203b1922265f7df1d988aceeb727fa 434 PIRSF PIRSF003095 5 434 3.5E-123 T 28-03-2018 IPR005215 Trigger factor GO:0015031 CIG75_RS07835 72203b1922265f7df1d988aceeb727fa 434 SUPERFAMILY SSF102735 7 131 4.45E-36 T 28-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 CIG75_RS07835 72203b1922265f7df1d988aceeb727fa 434 Pfam PF05697 Bacterial trigger factor protein (TF) 7 148 5.0E-39 T 28-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 CIG75_RS07835 72203b1922265f7df1d988aceeb727fa 434 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 267 429 1.3E-43 T 28-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 CIG75_RS07835 72203b1922265f7df1d988aceeb727fa 434 Hamap MF_00303 Trigger factor [tig]. 4 434 21.76 T 28-03-2018 IPR005215 Trigger factor GO:0015031 CIG75_RS12090 c481858aaba77ed6361ddb2b45d84cbc 467 SMART SM00382 52 356 5.3E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS12090 c481858aaba77ed6361ddb2b45d84cbc 467 SUPERFAMILY SSF52540 7 465 1.09E-83 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS12090 c481858aaba77ed6361ddb2b45d84cbc 467 Gene3D G3DSA:1.10.8.10 113 225 1.6E-25 T 28-03-2018 CIG75_RS12090 c481858aaba77ed6361ddb2b45d84cbc 467 Gene3D G3DSA:1.10.8.60 359 455 4.1E-29 T 28-03-2018 CIG75_RS12090 c481858aaba77ed6361ddb2b45d84cbc 467 SMART SM01086 359 458 4.5E-22 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CIG75_RS12090 c481858aaba77ed6361ddb2b45d84cbc 467 Gene3D G3DSA:3.40.50.300 25 102 0.0048 T 28-03-2018 CIG75_RS12090 c481858aaba77ed6361ddb2b45d84cbc 467 Pfam PF07724 AAA domain (Cdc48 subfamily) 215 353 9.0E-40 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CIG75_RS12090 c481858aaba77ed6361ddb2b45d84cbc 467 TIGRFAM TIGR00390 hslU: ATP-dependent protease HslVU, ATPase subunit 7 467 1.7E-199 T 28-03-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 CIG75_RS12090 c481858aaba77ed6361ddb2b45d84cbc 467 Hamap MF_00249 ATP-dependent protease ATPase subunit HslU [hslU]. 4 467 43.379 T 28-03-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 CIG75_RS12090 c481858aaba77ed6361ddb2b45d84cbc 467 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 56 151 4.3E-7 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CIG75_RS12090 c481858aaba77ed6361ddb2b45d84cbc 467 Gene3D G3DSA:1.10.8.10 226 267 5.2E-17 T 28-03-2018 CIG75_RS12090 c481858aaba77ed6361ddb2b45d84cbc 467 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 359 430 9.6E-7 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CIG75_RS05205 d36d8cf95e357bb10872f1d0fdb8d0e6 331 SUPERFAMILY SSF102114 24 327 1.44E-69 T 28-03-2018 CIG75_RS05205 d36d8cf95e357bb10872f1d0fdb8d0e6 331 Hamap MF_01694 Biotin synthase [bioB]. 20 327 40.883 T 28-03-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CIG75_RS05205 d36d8cf95e357bb10872f1d0fdb8d0e6 331 Gene3D G3DSA:3.20.20.70 21 329 1.7E-47 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CIG75_RS05205 d36d8cf95e357bb10872f1d0fdb8d0e6 331 Pfam PF04055 Radical SAM superfamily 70 223 5.9E-15 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CIG75_RS05205 d36d8cf95e357bb10872f1d0fdb8d0e6 331 SMART SM00876 236 326 7.1E-35 T 28-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CIG75_RS05205 d36d8cf95e357bb10872f1d0fdb8d0e6 331 TIGRFAM TIGR00433 bioB: biotin synthase 32 325 1.6E-121 T 28-03-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CIG75_RS05205 d36d8cf95e357bb10872f1d0fdb8d0e6 331 PIRSF PIRSF001619 3 331 1.4E-125 T 28-03-2018 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CIG75_RS05205 d36d8cf95e357bb10872f1d0fdb8d0e6 331 SMART SM00729 60 268 9.2E-30 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CIG75_RS05205 d36d8cf95e357bb10872f1d0fdb8d0e6 331 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 236 325 6.5E-16 T 28-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CIG75_RS11305 bff6d9f6ce80341181eaf56acce693dd 111 SMART SM00418 3 77 5.1E-21 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CIG75_RS11305 bff6d9f6ce80341181eaf56acce693dd 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 37 52 3.6E-9 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CIG75_RS11305 bff6d9f6ce80341181eaf56acce693dd 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 52 67 3.6E-9 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CIG75_RS11305 bff6d9f6ce80341181eaf56acce693dd 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 5 20 3.6E-9 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CIG75_RS11305 bff6d9f6ce80341181eaf56acce693dd 111 Gene3D G3DSA:1.10.10.10 1 104 9.7E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS11305 bff6d9f6ce80341181eaf56acce693dd 111 Pfam PF12840 Helix-turn-helix domain 5 57 3.1E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS11305 bff6d9f6ce80341181eaf56acce693dd 111 SUPERFAMILY SSF46785 4 94 1.09E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS14580 e6ad35a21f36f2d536f7633abcde53f0 96 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 75 1.7E-20 T 28-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain CIG75_RS14580 e6ad35a21f36f2d536f7633abcde53f0 96 SUPERFAMILY SSF54909 1 79 3.43E-22 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CIG75_RS14580 e6ad35a21f36f2d536f7633abcde53f0 96 Gene3D G3DSA:3.30.70.100 1 96 4.7E-24 T 28-03-2018 CIG75_RS04440 21d1ccb9fd81120b18951a282403cb99 295 Gene3D G3DSA:3.40.109.30 182 278 7.2E-8 T 28-03-2018 CIG75_RS04440 21d1ccb9fd81120b18951a282403cb99 295 SUPERFAMILY SSF55469 185 272 3.66E-8 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CIG75_RS04440 21d1ccb9fd81120b18951a282403cb99 295 SUPERFAMILY SSF55469 11 183 2.22E-19 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CIG75_RS04440 21d1ccb9fd81120b18951a282403cb99 295 Gene3D G3DSA:3.40.109.10 7 181 9.9E-23 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CIG75_RS04440 21d1ccb9fd81120b18951a282403cb99 295 Pfam PF14512 Putative TM nitroreductase 16 260 1.2E-39 T 28-03-2018 IPR029478 Putative nitroreductase TM1586 CIG75_RS07160 3ad91175fea3593c926b738866afba8e 273 Gene3D G3DSA:3.40.50.620 10 266 2.7E-55 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CIG75_RS07160 3ad91175fea3593c926b738866afba8e 273 SUPERFAMILY SSF52402 14 261 3.75E-63 T 28-03-2018 CIG75_RS07160 3ad91175fea3593c926b738866afba8e 273 TIGRFAM TIGR00552 nadE: NAD+ synthetase 17 260 6.4E-59 T 28-03-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 CIG75_RS07160 3ad91175fea3593c926b738866afba8e 273 Pfam PF02540 NAD synthase 20 256 3.0E-59 T 28-03-2018 IPR022310 NAD/GMP synthase CIG75_RS06355 69d18905dcc0ca7f8fe2e634fdea9716 86 PRINTS PR01853 Bacterial YajC preprotein translocase signature 4 24 2.7E-13 T 28-03-2018 IPR003849 Preprotein translocase YajC CIG75_RS06355 69d18905dcc0ca7f8fe2e634fdea9716 86 PRINTS PR01853 Bacterial YajC preprotein translocase signature 42 60 2.7E-13 T 28-03-2018 IPR003849 Preprotein translocase YajC CIG75_RS06355 69d18905dcc0ca7f8fe2e634fdea9716 86 SMART SM01323 2 84 2.4E-37 T 28-03-2018 IPR003849 Preprotein translocase YajC CIG75_RS06355 69d18905dcc0ca7f8fe2e634fdea9716 86 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 3 84 2.4E-26 T 28-03-2018 IPR003849 Preprotein translocase YajC CIG75_RS06355 69d18905dcc0ca7f8fe2e634fdea9716 86 Pfam PF02699 Preprotein translocase subunit 6 81 1.6E-27 T 28-03-2018 IPR003849 Preprotein translocase YajC CIG75_RS04140 e484e0c8432777ea643193933c4302db 735 Pfam PF12102 Domain of unknown function (DUF3578) 146 324 1.5E-44 T 28-03-2018 IPR021961 Protein of unknown function DUF3578 CIG75_RS04140 e484e0c8432777ea643193933c4302db 735 Gene3D G3DSA:3.40.50.300 346 553 3.1E-21 T 28-03-2018 CIG75_RS04140 e484e0c8432777ea643193933c4302db 735 Pfam PF07728 AAA domain (dynein-related subfamily) 384 534 6.1E-10 T 28-03-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 CIG75_RS04140 e484e0c8432777ea643193933c4302db 735 SMART SM00382 380 564 0.0049 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS04140 e484e0c8432777ea643193933c4302db 735 SUPERFAMILY SSF52540 543 660 1.55E-5 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS04140 e484e0c8432777ea643193933c4302db 735 SUPERFAMILY SSF52540 365 409 1.55E-5 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS04140 e484e0c8432777ea643193933c4302db 735 SUPERFAMILY SSF52540 378 562 4.68E-17 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS08000 255bd357d38335fce89b58f2a2eda335 475 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 95 109 1.5E-19 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CIG75_RS08000 255bd357d38335fce89b58f2a2eda335 475 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 240 255 1.5E-19 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CIG75_RS08000 255bd357d38335fce89b58f2a2eda335 475 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 178 197 1.5E-19 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CIG75_RS08000 255bd357d38335fce89b58f2a2eda335 475 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 212 225 1.5E-19 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CIG75_RS08000 255bd357d38335fce89b58f2a2eda335 475 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 268 373 4.8E-25 T 28-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CIG75_RS08000 255bd357d38335fce89b58f2a2eda335 475 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 172 260 3.5E-28 T 28-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CIG75_RS08000 255bd357d38335fce89b58f2a2eda335 475 SUPERFAMILY SSF53738 170 263 2.24E-27 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CIG75_RS08000 255bd357d38335fce89b58f2a2eda335 475 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 96 105 - T 28-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CIG75_RS08000 255bd357d38335fce89b58f2a2eda335 475 SUPERFAMILY SSF53738 248 382 2.2E-28 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CIG75_RS08000 255bd357d38335fce89b58f2a2eda335 475 Gene3D G3DSA:3.40.120.10 1 168 5.6E-42 T 28-03-2018 CIG75_RS08000 255bd357d38335fce89b58f2a2eda335 475 Gene3D G3DSA:3.40.120.10 169 267 2.7E-30 T 28-03-2018 CIG75_RS08000 255bd357d38335fce89b58f2a2eda335 475 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 4 132 3.9E-37 T 28-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CIG75_RS08000 255bd357d38335fce89b58f2a2eda335 475 SUPERFAMILY SSF53738 3 185 1.22E-40 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CIG75_RS08000 255bd357d38335fce89b58f2a2eda335 475 SUPERFAMILY SSF55957 371 467 4.32E-20 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CIG75_RS08000 255bd357d38335fce89b58f2a2eda335 475 Gene3D G3DSA:3.30.310.50 378 467 4.4E-23 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CIG75_RS08000 255bd357d38335fce89b58f2a2eda335 475 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 399 465 2.2E-12 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CIG75_RS08000 255bd357d38335fce89b58f2a2eda335 475 Gene3D G3DSA:3.40.120.10 268 374 2.0E-26 T 28-03-2018 CIG75_RS08860 d8a86caf8f255508a152b1d57397ae64 237 Gene3D G3DSA:1.10.10.10 128 237 8.4E-37 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS08860 d8a86caf8f255508a152b1d57397ae64 237 SMART SM00448 4 115 1.3E-47 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CIG75_RS08860 d8a86caf8f255508a152b1d57397ae64 237 SUPERFAMILY SSF52172 1 187 5.42E-45 T 28-03-2018 IPR011006 CheY-like superfamily CIG75_RS08860 d8a86caf8f255508a152b1d57397ae64 237 SMART SM00862 156 233 2.0E-30 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CIG75_RS08860 d8a86caf8f255508a152b1d57397ae64 237 Pfam PF00486 Transcriptional regulatory protein, C terminal 156 233 4.0E-29 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CIG75_RS08860 d8a86caf8f255508a152b1d57397ae64 237 Gene3D G3DSA:3.40.50.2300 1 127 3.2E-40 T 28-03-2018 CIG75_RS08860 d8a86caf8f255508a152b1d57397ae64 237 Pfam PF00072 Response regulator receiver domain 6 115 8.2E-32 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CIG75_RS02820 54969c51c75697f1e923b6874b32e259 246 Gene3D G3DSA:3.40.50.1820 12 246 9.7E-28 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS02820 54969c51c75697f1e923b6874b32e259 246 Pfam PF00975 Thioesterase domain 16 242 1.8E-39 T 28-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CIG75_RS02820 54969c51c75697f1e923b6874b32e259 246 SUPERFAMILY SSF53474 12 243 1.49E-46 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS08845 bf638d97e4d31a3658c2fb8c4e65d060 181 Pfam PF00578 AhpC/TSA family 41 158 1.9E-34 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CIG75_RS08845 bf638d97e4d31a3658c2fb8c4e65d060 181 Gene3D G3DSA:3.40.30.10 26 170 8.8E-41 T 28-03-2018 CIG75_RS08845 bf638d97e4d31a3658c2fb8c4e65d060 181 ProSitePatterns PS00194 Thioredoxin family active site. 69 87 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 CIG75_RS08845 bf638d97e4d31a3658c2fb8c4e65d060 181 SUPERFAMILY SSF52833 38 177 1.83E-43 T 28-03-2018 IPR012336 Thioredoxin-like fold CIG75_RS12900 043e2fb44546b5c715f9923d96c8e349 460 Pfam PF00772 DnaB-like helicase N terminal domain 14 117 1.2E-29 T 28-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CIG75_RS12900 043e2fb44546b5c715f9923d96c8e349 460 Pfam PF03796 DnaB-like helicase C terminal domain 195 447 5.2E-113 T 28-03-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 CIG75_RS12900 043e2fb44546b5c715f9923d96c8e349 460 Gene3D G3DSA:1.10.860.10 5 157 2.3E-38 T 28-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal CIG75_RS12900 043e2fb44546b5c715f9923d96c8e349 460 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 15 449 4.7E-167 T 28-03-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 CIG75_RS12900 043e2fb44546b5c715f9923d96c8e349 460 SUPERFAMILY SSF48024 14 125 3.01E-31 T 28-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CIG75_RS12900 043e2fb44546b5c715f9923d96c8e349 460 Gene3D G3DSA:3.40.50.300 175 455 8.5E-70 T 28-03-2018 CIG75_RS12900 043e2fb44546b5c715f9923d96c8e349 460 SUPERFAMILY SSF52540 193 441 1.06E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS15320 7968363314ef940868b8eb959ce14449 259 SMART SM00382 27 231 1.8E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS15320 7968363314ef940868b8eb959ce14449 259 TIGRFAM TIGR02315 ABC_phnC: phosphonate ABC transporter, ATP-binding protein 1 243 2.4E-107 T 28-03-2018 IPR012693 ABC transporter, phosphonate import, PhnC GO:0005524|GO:0015416|GO:0015716|GO:0016020 CIG75_RS15320 7968363314ef940868b8eb959ce14449 259 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS15320 7968363314ef940868b8eb959ce14449 259 Gene3D G3DSA:3.40.50.300 1 250 7.4E-61 T 28-03-2018 CIG75_RS15320 7968363314ef940868b8eb959ce14449 259 Pfam PF00005 ABC transporter 18 174 1.5E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS15320 7968363314ef940868b8eb959ce14449 259 SUPERFAMILY SSF52540 1 236 6.9E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS18675 aece3cb5d925b01162154190af53d7b2 226 Gene3D G3DSA:3.40.50.880 1 222 8.2E-39 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CIG75_RS18675 aece3cb5d925b01162154190af53d7b2 226 PIRSF PIRSF001586 1 223 5.4E-88 T 28-03-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CIG75_RS18675 aece3cb5d925b01162154190af53d7b2 226 SUPERFAMILY SSF52317 1 220 1.67E-77 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CIG75_RS18675 aece3cb5d925b01162154190af53d7b2 226 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 1 219 7.7E-94 T 28-03-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CIG75_RS18675 aece3cb5d925b01162154190af53d7b2 226 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 1 218 44.411 T 28-03-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CIG75_RS18675 aece3cb5d925b01162154190af53d7b2 226 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 2 204 8.2E-46 T 28-03-2018 CIG75_RS18675 aece3cb5d925b01162154190af53d7b2 226 SMART SM01211 1 220 2.8E-138 T 28-03-2018 CIG75_RS14105 402b0b55a95f63d9bce62b9132d82338 131 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 23 126 2.7E-21 T 28-03-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA CIG75_RS14105 402b0b55a95f63d9bce62b9132d82338 131 Gene3D G3DSA:1.20.1500.10 20 128 1.0E-25 T 28-03-2018 IPR023378 YheA/YmcA-like domain CIG75_RS14105 402b0b55a95f63d9bce62b9132d82338 131 SUPERFAMILY SSF158622 17 128 3.14E-26 T 28-03-2018 IPR023378 YheA/YmcA-like domain CIG75_RS14105 402b0b55a95f63d9bce62b9132d82338 131 PIRSF PIRSF021287 13 131 6.3E-21 T 28-03-2018 IPR016783 Biofilm formation YmcA CIG75_RS18940 63159fd73e3538d08d465d866f6168bd 322 SUPERFAMILY SSF69279 19 139 2.25E-12 T 28-03-2018 CIG75_RS18940 63159fd73e3538d08d465d866f6168bd 322 Gene3D G3DSA:2.30.300.10 95 320 6.6E-5 T 28-03-2018 CIG75_RS01655 70fb89bc6d8d37ad25873d4ed51bed89 312 SUPERFAMILY SSF56112 19 216 1.75E-25 T 28-03-2018 IPR011009 Protein kinase-like domain CIG75_RS01655 70fb89bc6d8d37ad25873d4ed51bed89 312 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 34 56 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 CIG75_RS01655 70fb89bc6d8d37ad25873d4ed51bed89 312 Gene3D G3DSA:1.10.510.10 22 281 4.5E-23 T 28-03-2018 CIG75_RS01655 70fb89bc6d8d37ad25873d4ed51bed89 312 SMART SM00220 28 223 7.0E-7 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CIG75_RS01655 70fb89bc6d8d37ad25873d4ed51bed89 312 Pfam PF00069 Protein kinase domain 30 215 9.3E-18 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CIG75_RS06840 c198110388697c47e63145b06665fb41 538 SMART SM00287 199 261 0.073 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type CIG75_RS06840 c198110388697c47e63145b06665fb41 538 SMART SM00287 276 338 4.6E-8 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type CIG75_RS06840 c198110388697c47e63145b06665fb41 538 SMART SM00287 53 115 1.0E-9 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type CIG75_RS06840 c198110388697c47e63145b06665fb41 538 SMART SM00287 123 187 2.1E-11 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type CIG75_RS06840 c198110388697c47e63145b06665fb41 538 PIRSF PIRSF037846 24 133 2.7E-12 T 28-03-2018 IPR017293 N-acetylmuramoyl-L-alanine amidase, YrvJ, predicted CIG75_RS06840 c198110388697c47e63145b06665fb41 538 PIRSF PIRSF037846 117 534 2.3E-99 T 28-03-2018 IPR017293 N-acetylmuramoyl-L-alanine amidase, YrvJ, predicted CIG75_RS06840 c198110388697c47e63145b06665fb41 538 Gene3D G3DSA:2.30.30.410 116 190 2.5E-15 T 28-03-2018 CIG75_RS06840 c198110388697c47e63145b06665fb41 538 Gene3D G3DSA:3.40.630.40 355 538 5.2E-52 T 28-03-2018 CIG75_RS06840 c198110388697c47e63145b06665fb41 538 SUPERFAMILY SSF50044 224 264 2.59E-5 T 28-03-2018 IPR001452 SH3 domain GO:0005515 CIG75_RS06840 c198110388697c47e63145b06665fb41 538 Gene3D G3DSA:2.40.50.110 14 115 4.9E-14 T 28-03-2018 CIG75_RS06840 c198110388697c47e63145b06665fb41 538 Gene3D G3DSA:2.40.50.110 266 338 6.6E-11 T 28-03-2018 CIG75_RS06840 c198110388697c47e63145b06665fb41 538 Gene3D G3DSA:2.40.50.110 191 260 7.9E-16 T 28-03-2018 CIG75_RS06840 c198110388697c47e63145b06665fb41 538 SMART SM00646 420 530 3.4E-26 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CIG75_RS06840 c198110388697c47e63145b06665fb41 538 SUPERFAMILY SSF53187 357 533 3.14E-48 T 28-03-2018 CIG75_RS06840 c198110388697c47e63145b06665fb41 538 Pfam PF08239 Bacterial SH3 domain 286 334 5.2E-7 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type CIG75_RS06840 c198110388697c47e63145b06665fb41 538 Pfam PF08239 Bacterial SH3 domain 135 184 9.3E-11 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type CIG75_RS06840 c198110388697c47e63145b06665fb41 538 Pfam PF08239 Bacterial SH3 domain 208 258 8.3E-12 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type CIG75_RS06840 c198110388697c47e63145b06665fb41 538 Pfam PF08239 Bacterial SH3 domain 63 112 1.5E-11 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type CIG75_RS06840 c198110388697c47e63145b06665fb41 538 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 360 530 2.8E-44 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CIG75_RS17135 e0cbad49d420a8d2c02087799bac837a 229 Pfam PF03167 Uracil DNA glycosylase superfamily 46 213 2.4E-31 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CIG75_RS17135 e0cbad49d420a8d2c02087799bac837a 229 SMART SM00987 46 217 4.0E-34 T 28-03-2018 CIG75_RS17135 e0cbad49d420a8d2c02087799bac837a 229 SMART SM00986 46 217 4.0E-34 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CIG75_RS17135 e0cbad49d420a8d2c02087799bac837a 229 Gene3D G3DSA:3.40.470.10 2 223 2.2E-50 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CIG75_RS17135 e0cbad49d420a8d2c02087799bac837a 229 SUPERFAMILY SSF52141 14 225 1.08E-48 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CIG75_RS07605 ac6e9b82130555a386eb40ae1f41c2e9 411 Gene3D G3DSA:2.60.40.1220 23 120 6.5E-17 T 28-03-2018 CIG75_RS07605 ac6e9b82130555a386eb40ae1f41c2e9 411 Pfam PF04234 CopC domain 24 118 6.7E-16 T 28-03-2018 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 CIG75_RS07605 ac6e9b82130555a386eb40ae1f41c2e9 411 SUPERFAMILY SSF81296 23 119 1.47E-17 T 28-03-2018 IPR014756 Immunoglobulin E-set CIG75_RS10040 3183f253dd260fc419437efbbfa3938a 434 Pfam PF07676 WD40-like Beta Propeller Repeat 58 86 3.1E-8 T 28-03-2018 IPR011659 WD40-like Beta Propeller CIG75_RS10040 3183f253dd260fc419437efbbfa3938a 434 SUPERFAMILY SSF82171 66 409 4.58E-21 T 28-03-2018 CIG75_RS10040 3183f253dd260fc419437efbbfa3938a 434 Gene3D G3DSA:2.130.10.150 336 431 0.043 T 28-03-2018 CIG75_RS10040 3183f253dd260fc419437efbbfa3938a 434 Gene3D G3DSA:2.130.10.150 31 187 6.5E-19 T 28-03-2018 CIG75_RS10040 3183f253dd260fc419437efbbfa3938a 434 Gene3D G3DSA:2.130.10.150 188 335 7.0E-7 T 28-03-2018 CIG75_RS06295 dfb2f3ba0f96d55184b2b655fcfde19d 225 Pfam PF00027 Cyclic nucleotide-binding domain 30 116 6.0E-22 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CIG75_RS06295 dfb2f3ba0f96d55184b2b655fcfde19d 225 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 173 189 2.3E-5 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CIG75_RS06295 dfb2f3ba0f96d55184b2b655fcfde19d 225 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 189 204 2.3E-5 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CIG75_RS06295 dfb2f3ba0f96d55184b2b655fcfde19d 225 Gene3D G3DSA:2.60.120.10 4 137 7.8E-31 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CIG75_RS06295 dfb2f3ba0f96d55184b2b655fcfde19d 225 SUPERFAMILY SSF51206 5 143 2.09E-38 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like CIG75_RS06295 dfb2f3ba0f96d55184b2b655fcfde19d 225 SMART SM00419 167 215 1.8E-9 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CIG75_RS06295 dfb2f3ba0f96d55184b2b655fcfde19d 225 Pfam PF13545 Crp-like helix-turn-helix domain 149 220 7.7E-16 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CIG75_RS06295 dfb2f3ba0f96d55184b2b655fcfde19d 225 SMART SM00100 10 128 1.0E-20 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CIG75_RS06295 dfb2f3ba0f96d55184b2b655fcfde19d 225 Gene3D G3DSA:1.10.10.10 138 223 1.9E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS06295 dfb2f3ba0f96d55184b2b655fcfde19d 225 SUPERFAMILY SSF46785 146 220 1.78E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS14715 d0bee1c3df344e59c0cf84d81068c4e9 132 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 53 93 - T 28-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 CIG75_RS14715 d0bee1c3df344e59c0cf84d81068c4e9 132 TIGRFAM TIGR01354 cyt_deam_tetra: cytidine deaminase 6 129 5.4E-48 T 28-03-2018 IPR006262 Cytidine deaminase, homotetrameric GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199|Reactome: R-HSA-6798695|Reactome: R-HSA-73614 CIG75_RS14715 d0bee1c3df344e59c0cf84d81068c4e9 132 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 3 99 1.8E-17 T 28-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain CIG75_RS14715 d0bee1c3df344e59c0cf84d81068c4e9 132 Gene3D G3DSA:3.40.140.10 1 132 9.1E-52 T 28-03-2018 CIG75_RS14715 d0bee1c3df344e59c0cf84d81068c4e9 132 SUPERFAMILY SSF53927 3 129 4.35E-48 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CIG75_RS20085 4fddf3d8954a66db7e34e2d35de55aa1 332 SUPERFAMILY SSF51395 11 320 1.54E-90 T 28-03-2018 CIG75_RS20085 4fddf3d8954a66db7e34e2d35de55aa1 332 PIRSF PIRSF006621 1 329 1.4E-111 T 28-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 CIG75_RS20085 4fddf3d8954a66db7e34e2d35de55aa1 332 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 95 113 - T 28-03-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 CIG75_RS20085 4fddf3d8954a66db7e34e2d35de55aa1 332 Gene3D G3DSA:1.10.1200.80 262 331 2.5E-22 T 28-03-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 CIG75_RS20085 4fddf3d8954a66db7e34e2d35de55aa1 332 Pfam PF01207 Dihydrouridine synthase (Dus) 14 316 4.7E-107 T 28-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 CIG75_RS20085 4fddf3d8954a66db7e34e2d35de55aa1 332 Gene3D G3DSA:3.20.20.70 7 261 3.0E-56 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CIG75_RS20085 4fddf3d8954a66db7e34e2d35de55aa1 332 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 4 320 9.9E-126 T 28-03-2018 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 CIG75_RS02875 5f18efd1937a15d98f2745ed97f16968 260 Gene3D G3DSA:3.90.1530.10 14 100 1.3E-7 T 28-03-2018 CIG75_RS02875 5f18efd1937a15d98f2745ed97f16968 260 SUPERFAMILY SSF110849 173 227 5.02E-21 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CIG75_RS02875 5f18efd1937a15d98f2745ed97f16968 260 SUPERFAMILY SSF110849 16 133 5.02E-21 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CIG75_RS02875 5f18efd1937a15d98f2745ed97f16968 260 PIRSF PIRSF032543 9 260 1.2E-48 T 28-03-2018 IPR016999 Uncharacterised conserved protein UCP032543, ParB-like nuclease CIG75_RS02875 5f18efd1937a15d98f2745ed97f16968 260 Pfam PF02195 ParB-like nuclease domain 33 91 1.1E-6 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CIG75_RS05220 516d7e73282d50aa0d36e6f6cff20e1c 175 SUPERFAMILY SSF52141 10 171 1.09E-36 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CIG75_RS05220 516d7e73282d50aa0d36e6f6cff20e1c 175 Pfam PF03167 Uracil DNA glycosylase superfamily 13 160 2.3E-17 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CIG75_RS05220 516d7e73282d50aa0d36e6f6cff20e1c 175 Gene3D G3DSA:3.40.470.10 13 175 3.9E-45 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CIG75_RS03370 739753c88442705cb048cf425fca7c7d 456 Gene3D G3DSA:1.10.45.10 415 454 1.6E-16 T 28-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 CIG75_RS03370 739753c88442705cb048cf425fca7c7d 456 Gene3D G3DSA:3.30.43.10 2 92 2.7E-23 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CIG75_RS03370 739753c88442705cb048cf425fca7c7d 456 Pfam PF02913 FAD linked oxidases, C-terminal domain 214 454 7.4E-55 T 28-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 CIG75_RS03370 739753c88442705cb048cf425fca7c7d 456 SUPERFAMILY SSF56176 12 214 5.61E-66 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CIG75_RS03370 739753c88442705cb048cf425fca7c7d 456 Gene3D G3DSA:3.30.465.10 93 236 7.5E-44 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CIG75_RS03370 739753c88442705cb048cf425fca7c7d 456 SUPERFAMILY SSF55103 217 455 1.03E-60 T 28-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CIG75_RS03370 739753c88442705cb048cf425fca7c7d 456 Pfam PF01565 FAD binding domain 40 177 6.5E-42 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CIG75_RS08250 f99c67feaa0834d8cb12a48ab966ba81 566 SMART SM00487 66 242 2.1E-32 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CIG75_RS08250 f99c67feaa0834d8cb12a48ab966ba81 566 Gene3D G3DSA:3.40.50.300 357 517 1.3E-36 T 28-03-2018 CIG75_RS08250 f99c67feaa0834d8cb12a48ab966ba81 566 SMART SM00490 400 480 6.2E-23 T 28-03-2018 IPR001650 Helicase, C-terminal CIG75_RS08250 f99c67feaa0834d8cb12a48ab966ba81 566 Pfam PF00271 Helicase conserved C-terminal domain 374 480 2.2E-24 T 28-03-2018 IPR001650 Helicase, C-terminal CIG75_RS08250 f99c67feaa0834d8cb12a48ab966ba81 566 Pfam PF00176 SNF2 family N-terminal domain 89 336 2.5E-37 T 28-03-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 CIG75_RS08250 f99c67feaa0834d8cb12a48ab966ba81 566 SUPERFAMILY SSF52540 38 269 2.96E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS08250 f99c67feaa0834d8cb12a48ab966ba81 566 Gene3D G3DSA:3.40.50.10810 46 288 1.2E-40 T 28-03-2018 CIG75_RS08250 f99c67feaa0834d8cb12a48ab966ba81 566 SUPERFAMILY SSF52540 278 528 3.34E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS10190 b032a0fc11921daa2fe3c542255cb090 241 SMART SM00866 94 234 5.4E-46 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CIG75_RS10190 b032a0fc11921daa2fe3c542255cb090 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 63 3.5E-10 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CIG75_RS10190 b032a0fc11921daa2fe3c542255cb090 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 47 3.5E-10 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CIG75_RS10190 b032a0fc11921daa2fe3c542255cb090 241 SUPERFAMILY SSF46785 2 86 7.09E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS10190 b032a0fc11921daa2fe3c542255cb090 241 Pfam PF07702 UTRA domain 94 234 1.4E-42 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CIG75_RS10190 b032a0fc11921daa2fe3c542255cb090 241 SMART SM00345 14 73 1.3E-20 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CIG75_RS10190 b032a0fc11921daa2fe3c542255cb090 241 Gene3D G3DSA:3.40.1410.10 73 241 5.8E-52 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CIG75_RS10190 b032a0fc11921daa2fe3c542255cb090 241 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 73 5.4E-22 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CIG75_RS10190 b032a0fc11921daa2fe3c542255cb090 241 Gene3D G3DSA:1.10.10.10 1 72 4.2E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS10190 b032a0fc11921daa2fe3c542255cb090 241 SUPERFAMILY SSF64288 61 241 7.38E-56 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CIG75_RS04905 d868d9fcc79425ed6b507c662bf274e9 93 Pfam PF13828 Domain of unknown function (DUF4190) 13 84 1.1E-11 T 28-03-2018 IPR025241 Domain of unknown function DUF4190 CIG75_RS19880 1765d922de13f467aa216d1e5a6d2317 811 SUPERFAMILY SSF81923 5 149 7.16E-33 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CIG75_RS19880 1765d922de13f467aa216d1e5a6d2317 811 Gene3D G3DSA:1.10.8.60 727 806 3.9E-26 T 28-03-2018 CIG75_RS19880 1765d922de13f467aa216d1e5a6d2317 811 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 712 791 4.2E-28 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CIG75_RS19880 1765d922de13f467aa216d1e5a6d2317 811 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 614 632 4.7E-43 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CIG75_RS19880 1765d922de13f467aa216d1e5a6d2317 811 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 585 603 4.7E-43 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CIG75_RS19880 1765d922de13f467aa216d1e5a6d2317 811 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 540 558 4.7E-43 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CIG75_RS19880 1765d922de13f467aa216d1e5a6d2317 811 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 647 661 4.7E-43 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CIG75_RS19880 1765d922de13f467aa216d1e5a6d2317 811 SUPERFAMILY SSF52540 485 799 1.95E-79 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS19880 1765d922de13f467aa216d1e5a6d2317 811 Gene3D G3DSA:3.40.50.300 486 726 1.2E-53 T 28-03-2018 CIG75_RS19880 1765d922de13f467aa216d1e5a6d2317 811 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 69 2.2E-15 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CIG75_RS19880 1765d922de13f467aa216d1e5a6d2317 811 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 93 143 3.4E-18 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CIG75_RS19880 1765d922de13f467aa216d1e5a6d2317 811 Gene3D G3DSA:1.10.1780.10 1 78 2.9E-24 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CIG75_RS19880 1765d922de13f467aa216d1e5a6d2317 811 SUPERFAMILY SSF52540 160 466 3.5E-76 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS19880 1765d922de13f467aa216d1e5a6d2317 811 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 294 306 - T 28-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 CIG75_RS19880 1765d922de13f467aa216d1e5a6d2317 811 SMART SM00382 536 684 6.0E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS19880 1765d922de13f467aa216d1e5a6d2317 811 SMART SM00382 199 342 2.6E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS19880 1765d922de13f467aa216d1e5a6d2317 811 Pfam PF02151 UvrB/uvrC motif 416 450 7.1E-7 T 28-03-2018 IPR001943 UVR domain GO:0005515 CIG75_RS19880 1765d922de13f467aa216d1e5a6d2317 811 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 204 333 3.0E-13 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CIG75_RS19880 1765d922de13f467aa216d1e5a6d2317 811 Gene3D G3DSA:1.10.1780.10 79 192 2.7E-30 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CIG75_RS19880 1765d922de13f467aa216d1e5a6d2317 811 Gene3D G3DSA:1.10.8.60 344 485 1.1E-43 T 28-03-2018 CIG75_RS19880 1765d922de13f467aa216d1e5a6d2317 811 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 570 588 - T 28-03-2018 IPR028299 ClpA/B, conserved site 2 CIG75_RS19880 1765d922de13f467aa216d1e5a6d2317 811 Pfam PF07724 AAA domain (Cdc48 subfamily) 535 705 8.0E-55 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CIG75_RS19880 1765d922de13f467aa216d1e5a6d2317 811 SMART SM01086 712 801 7.3E-40 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CIG75_RS19880 1765d922de13f467aa216d1e5a6d2317 811 Gene3D G3DSA:3.40.50.300 193 341 1.0E-19 T 28-03-2018 CIG75_RS09665 4e573bf344904fd87da5e8f4f1bcaa5e 148 SMART SM00562 3 140 1.8E-82 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CIG75_RS09665 4e573bf344904fd87da5e8f4f1bcaa5e 148 Pfam PF00334 Nucleoside diphosphate kinase 4 135 5.4E-56 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CIG75_RS09665 4e573bf344904fd87da5e8f4f1bcaa5e 148 Gene3D G3DSA:3.30.70.141 2 142 1.9E-55 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CIG75_RS09665 4e573bf344904fd87da5e8f4f1bcaa5e 148 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 3 138 35.399 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CIG75_RS09665 4e573bf344904fd87da5e8f4f1bcaa5e 148 PRINTS PR01243 Nucleoside diphosphate kinase signature 6 28 1.6E-51 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CIG75_RS09665 4e573bf344904fd87da5e8f4f1bcaa5e 148 PRINTS PR01243 Nucleoside diphosphate kinase signature 50 69 1.6E-51 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CIG75_RS09665 4e573bf344904fd87da5e8f4f1bcaa5e 148 PRINTS PR01243 Nucleoside diphosphate kinase signature 114 133 1.6E-51 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CIG75_RS09665 4e573bf344904fd87da5e8f4f1bcaa5e 148 PRINTS PR01243 Nucleoside diphosphate kinase signature 70 87 1.6E-51 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CIG75_RS09665 4e573bf344904fd87da5e8f4f1bcaa5e 148 PRINTS PR01243 Nucleoside diphosphate kinase signature 91 107 1.6E-51 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CIG75_RS09665 4e573bf344904fd87da5e8f4f1bcaa5e 148 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 114 122 - T 28-03-2018 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CIG75_RS09665 4e573bf344904fd87da5e8f4f1bcaa5e 148 SUPERFAMILY SSF54919 1 137 4.19E-59 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CIG75_RS07915 e535056d2b87e8f11e5abaa083a89804 429 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 238 274 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CIG75_RS07915 e535056d2b87e8f11e5abaa083a89804 429 Pfam PF00202 Aminotransferase class-III 37 420 9.0E-77 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CIG75_RS07915 e535056d2b87e8f11e5abaa083a89804 429 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 8 428 2.3E-194 T 28-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 CIG75_RS07915 e535056d2b87e8f11e5abaa083a89804 429 Gene3D G3DSA:3.40.640.10 172 315 1.6E-42 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CIG75_RS07915 e535056d2b87e8f11e5abaa083a89804 429 SUPERFAMILY SSF53383 5 428 5.18E-133 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CIG75_RS07915 e535056d2b87e8f11e5abaa083a89804 429 Gene3D G3DSA:3.90.1150.10 316 429 6.1E-18 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CIG75_RS07915 e535056d2b87e8f11e5abaa083a89804 429 Gene3D G3DSA:3.90.1150.10 1 171 1.8E-44 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CIG75_RS07915 e535056d2b87e8f11e5abaa083a89804 429 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 7 429 105.427 T 28-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 CIG75_RS02745 416749fed2380c3d5308637095a77416 322 Gene3D G3DSA:3.40.50.720 142 295 5.5E-13 T 28-03-2018 CIG75_RS02745 416749fed2380c3d5308637095a77416 322 PIRSF PIRSF001439 1 322 1.5E-52 T 28-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 CIG75_RS02745 416749fed2380c3d5308637095a77416 322 TIGRFAM TIGR03944 dehyd_SbnB_fam: 2,3-diaminopropionate biosynthesis protein SbnB 1 322 2.3E-102 T 28-03-2018 IPR023866 2,3-diaminopropionate biosynthesis protein SbnB CIG75_RS02745 416749fed2380c3d5308637095a77416 322 Gene3D G3DSA:3.30.1780.10 1 141 2.6E-30 T 28-03-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 CIG75_RS02745 416749fed2380c3d5308637095a77416 322 SUPERFAMILY SSF51735 1 321 8.79E-55 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS02745 416749fed2380c3d5308637095a77416 322 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 18 312 1.5E-30 T 28-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 CIG75_RS03275 257e2fa888ae22c853b99e93d1b0d637 362 SUPERFAMILY SSF55874 223 345 6.98E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS03275 257e2fa888ae22c853b99e93d1b0d637 362 Pfam PF07730 Histidine kinase 150 218 2.6E-19 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CIG75_RS03275 257e2fa888ae22c853b99e93d1b0d637 362 Pfam PF00672 HAMP domain 78 122 9.2E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CIG75_RS03275 257e2fa888ae22c853b99e93d1b0d637 362 PIRSF PIRSF037431 7 354 6.2E-119 T 28-03-2018 IPR017202 Sensor histidine kinase LiaS/VraS GO:0000155|GO:0000160|GO:0004673|GO:0016021 CIG75_RS03275 257e2fa888ae22c853b99e93d1b0d637 362 Gene3D G3DSA:3.30.565.10 215 354 4.8E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS03275 257e2fa888ae22c853b99e93d1b0d637 362 SMART SM00304 74 126 7.2E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CIG75_RS03275 257e2fa888ae22c853b99e93d1b0d637 362 SMART SM00387 255 348 5.2E-5 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS02765 42feabb45bb55447b2ca7d4a2e84530a 155 Pfam PF04657 Putative inner membrane exporter, YdcZ 5 138 2.3E-28 T 28-03-2018 IPR006750 Putative inner membrane exporter, YdcZ CIG75_RS02765 42feabb45bb55447b2ca7d4a2e84530a 155 SUPERFAMILY SSF103481 64 147 5.36E-6 T 28-03-2018 CIG75_RS04270 199d40892bc887b7f591ab883ab0293a 283 Pfam PF01145 SPFH domain / Band 7 family 56 228 2.8E-23 T 28-03-2018 IPR001107 Band 7 domain CIG75_RS04270 199d40892bc887b7f591ab883ab0293a 283 SMART SM00244 52 216 3.1E-9 T 28-03-2018 IPR001107 Band 7 domain CIG75_RS04270 199d40892bc887b7f591ab883ab0293a 283 SUPERFAMILY SSF117892 94 219 7.98E-10 T 28-03-2018 IPR001107 Band 7 domain CIG75_RS15890 7ea0546741e10f97e479cdde909c712f 609 Pfam PF00266 Aminotransferase class-V 260 529 2.1E-29 T 28-03-2018 IPR000192 Aminotransferase class V domain CIG75_RS15890 7ea0546741e10f97e479cdde909c712f 609 Gene3D G3DSA:3.90.550.10 1 240 8.5E-29 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CIG75_RS15890 7ea0546741e10f97e479cdde909c712f 609 SUPERFAMILY SSF53448 1 230 3.83E-31 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CIG75_RS15890 7ea0546741e10f97e479cdde909c712f 609 SUPERFAMILY SSF53383 245 598 4.69E-77 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CIG75_RS15890 7ea0546741e10f97e479cdde909c712f 609 Gene3D G3DSA:3.40.640.10 252 504 3.2E-33 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CIG75_RS15890 7ea0546741e10f97e479cdde909c712f 609 Pfam PF12804 MobA-like NTP transferase domain 3 110 9.0E-13 T 28-03-2018 IPR025877 MobA-like NTP transferase CIG75_RS15890 7ea0546741e10f97e479cdde909c712f 609 Gene3D G3DSA:3.90.1150.10 505 601 7.5E-23 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CIG75_RS19655 f472135147b245fa09aba8897bcaa337 122 SUPERFAMILY SSF53137 7 120 4.14E-57 T 28-03-2018 CIG75_RS19655 f472135147b245fa09aba8897bcaa337 122 Gene3D G3DSA:3.30.420.100 2 122 2.6E-45 T 28-03-2018 CIG75_RS19655 f472135147b245fa09aba8897bcaa337 122 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 7 122 1.3E-47 T 28-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS19655 f472135147b245fa09aba8897bcaa337 122 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 6 122 2.6E-51 T 28-03-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS19655 f472135147b245fa09aba8897bcaa337 122 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 6 122 30.202 T 28-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS17590 51b8fc075de88ceb9b288acee05341a8 462 Pfam PF14698 Argininosuccinate lyase C-terminal 363 431 1.0E-23 T 28-03-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CIG75_RS17590 51b8fc075de88ceb9b288acee05341a8 462 Gene3D G3DSA:1.10.275.10 2 106 2.0E-40 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal CIG75_RS17590 51b8fc075de88ceb9b288acee05341a8 462 Pfam PF00206 Lyase 6 300 2.5E-83 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal CIG75_RS17590 51b8fc075de88ceb9b288acee05341a8 462 PRINTS PR00145 Argininosuccinate lyase family signature 142 162 3.4E-70 T 28-03-2018 CIG75_RS17590 51b8fc075de88ceb9b288acee05341a8 462 PRINTS PR00145 Argininosuccinate lyase family signature 310 329 3.4E-70 T 28-03-2018 CIG75_RS17590 51b8fc075de88ceb9b288acee05341a8 462 PRINTS PR00145 Argininosuccinate lyase family signature 231 255 3.4E-70 T 28-03-2018 CIG75_RS17590 51b8fc075de88ceb9b288acee05341a8 462 PRINTS PR00145 Argininosuccinate lyase family signature 101 123 3.4E-70 T 28-03-2018 CIG75_RS17590 51b8fc075de88ceb9b288acee05341a8 462 PRINTS PR00145 Argininosuccinate lyase family signature 193 209 3.4E-70 T 28-03-2018 CIG75_RS17590 51b8fc075de88ceb9b288acee05341a8 462 PRINTS PR00145 Argininosuccinate lyase family signature 275 291 3.4E-70 T 28-03-2018 CIG75_RS17590 51b8fc075de88ceb9b288acee05341a8 462 Hamap MF_00006 Argininosuccinate lyase [argH]. 2 453 43.652 T 28-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CIG75_RS17590 51b8fc075de88ceb9b288acee05341a8 462 ProSitePatterns PS00163 Fumarate lyases signature. 275 284 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 CIG75_RS17590 51b8fc075de88ceb9b288acee05341a8 462 Gene3D G3DSA:1.10.40.30 375 432 1.1E-24 T 28-03-2018 CIG75_RS17590 51b8fc075de88ceb9b288acee05341a8 462 PRINTS PR00149 Fumarate lyase superfamily signature 102 120 7.1E-29 T 28-03-2018 IPR000362 Fumarate lyase family CIG75_RS17590 51b8fc075de88ceb9b288acee05341a8 462 PRINTS PR00149 Fumarate lyase superfamily signature 147 165 7.1E-29 T 28-03-2018 IPR000362 Fumarate lyase family CIG75_RS17590 51b8fc075de88ceb9b288acee05341a8 462 PRINTS PR00149 Fumarate lyase superfamily signature 275 291 7.1E-29 T 28-03-2018 IPR000362 Fumarate lyase family CIG75_RS17590 51b8fc075de88ceb9b288acee05341a8 462 PRINTS PR00149 Fumarate lyase superfamily signature 231 258 7.1E-29 T 28-03-2018 IPR000362 Fumarate lyase family CIG75_RS17590 51b8fc075de88ceb9b288acee05341a8 462 TIGRFAM TIGR00838 argH: argininosuccinate lyase 3 453 3.1E-196 T 28-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CIG75_RS17590 51b8fc075de88ceb9b288acee05341a8 462 SUPERFAMILY SSF48557 6 456 2.83E-154 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 CIG75_RS17590 51b8fc075de88ceb9b288acee05341a8 462 Gene3D G3DSA:1.20.200.10 107 374 4.3E-99 T 28-03-2018 CIG75_RS07910 d57fef0a63c62b2b02860c4d8fd0eec5 327 Pfam PF00490 Delta-aminolevulinic acid dehydratase 7 320 1.1E-148 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CIG75_RS07910 d57fef0a63c62b2b02860c4d8fd0eec5 327 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 190 209 1.7E-56 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CIG75_RS07910 d57fef0a63c62b2b02860c4d8fd0eec5 327 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 242 258 1.7E-56 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CIG75_RS07910 d57fef0a63c62b2b02860c4d8fd0eec5 327 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 122 136 1.7E-56 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CIG75_RS07910 d57fef0a63c62b2b02860c4d8fd0eec5 327 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 267 282 1.7E-56 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CIG75_RS07910 d57fef0a63c62b2b02860c4d8fd0eec5 327 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 297 316 1.7E-56 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CIG75_RS07910 d57fef0a63c62b2b02860c4d8fd0eec5 327 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 152 171 1.7E-56 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CIG75_RS07910 d57fef0a63c62b2b02860c4d8fd0eec5 327 Gene3D G3DSA:3.20.20.70 1 327 7.8E-152 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CIG75_RS07910 d57fef0a63c62b2b02860c4d8fd0eec5 327 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 242 254 - T 28-03-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CIG75_RS07910 d57fef0a63c62b2b02860c4d8fd0eec5 327 SMART SM01004 4 323 3.9E-226 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CIG75_RS07910 d57fef0a63c62b2b02860c4d8fd0eec5 327 SUPERFAMILY SSF51569 5 325 1.32E-140 T 28-03-2018 CIG75_RS07910 d57fef0a63c62b2b02860c4d8fd0eec5 327 PIRSF PIRSF001415 1 326 2.5E-149 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CIG75_RS03245 327d0530df644164f72630997e26e1d8 265 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 4 246 1.3E-61 T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CIG75_RS03245 327d0530df644164f72630997e26e1d8 265 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 5 253 14.417 T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CIG75_RS03245 327d0530df644164f72630997e26e1d8 265 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 6 254 2.1E-52 T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CIG75_RS00480 c1dd7e671652ca65151b7d6968961538 327 SUPERFAMILY SSF48179 185 304 3.74E-20 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CIG75_RS00480 c1dd7e671652ca65151b7d6968961538 327 SUPERFAMILY SSF51735 26 185 4.9E-32 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS00480 c1dd7e671652ca65151b7d6968961538 327 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 187 303 2.0E-15 T 28-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 CIG75_RS00480 c1dd7e671652ca65151b7d6968961538 327 Gene3D G3DSA:3.40.50.720 25 185 1.9E-21 T 28-03-2018 CIG75_RS00480 c1dd7e671652ca65151b7d6968961538 327 Gene3D G3DSA:1.10.1040.10 186 308 2.0E-17 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CIG75_RS00480 c1dd7e671652ca65151b7d6968961538 327 PIRSF PIRSF000103 18 309 4.1E-58 T 28-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CIG75_RS00480 c1dd7e671652ca65151b7d6968961538 327 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 26 183 6.2E-31 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CIG75_RS05180 ad9304b4901525216ec47b31f03daf81 83 SUPERFAMILY SSF88946 5 65 3.53E-9 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS05180 ad9304b4901525216ec47b31f03daf81 83 Gene3D G3DSA:1.10.1740.10 1 71 1.2E-9 T 28-03-2018 CIG75_RS05180 ad9304b4901525216ec47b31f03daf81 83 Pfam PF12645 Helix-turn-helix domain 8 63 6.6E-11 T 28-03-2018 IPR024760 Helix-turn-helix, conjugative transposon-like CIG75_RS10005 9ff3e7e8f4e452dfd32078b33fa8b7cb 258 TIGRFAM TIGR01446 DnaD_dom: DnaD domain protein 134 204 2.1E-22 T 28-03-2018 IPR006343 DnaD domain CIG75_RS10005 9ff3e7e8f4e452dfd32078b33fa8b7cb 258 SUPERFAMILY SSF158499 135 200 6.8E-20 T 28-03-2018 IPR006343 DnaD domain CIG75_RS10005 9ff3e7e8f4e452dfd32078b33fa8b7cb 258 Gene3D G3DSA:1.10.10.630 129 205 1.1E-23 T 28-03-2018 IPR034829 DnaD-like domain CIG75_RS10005 9ff3e7e8f4e452dfd32078b33fa8b7cb 258 Gene3D G3DSA:1.10.10.10 15 113 8.2E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS10005 9ff3e7e8f4e452dfd32078b33fa8b7cb 258 Pfam PF07261 Replication initiation and membrane attachment 136 204 3.4E-23 T 28-03-2018 IPR006343 DnaD domain CIG75_RS10005 9ff3e7e8f4e452dfd32078b33fa8b7cb 258 SUPERFAMILY SSF46785 18 86 7.94E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS11820 5e8117c86c4b7b254082d48d652417b2 153 SUPERFAMILY SSF75420 4 85 1.29E-27 T 28-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal CIG75_RS11820 5e8117c86c4b7b254082d48d652417b2 153 Gene3D G3DSA:3.30.300.70 1 82 1.6E-29 T 28-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal CIG75_RS11820 5e8117c86c4b7b254082d48d652417b2 153 Gene3D G3DSA:2.30.30.180 89 151 2.6E-18 T 28-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal CIG75_RS11820 5e8117c86c4b7b254082d48d652417b2 153 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 8 153 24.907 T 28-03-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 CIG75_RS11820 5e8117c86c4b7b254082d48d652417b2 153 Pfam PF02576 RimP N-terminal domain 14 85 1.6E-29 T 28-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal CIG75_RS11820 5e8117c86c4b7b254082d48d652417b2 153 Pfam PF17384 RimP C-terminal SH3 domain 88 153 2.4E-15 T 28-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal CIG75_RS11820 5e8117c86c4b7b254082d48d652417b2 153 SUPERFAMILY SSF74942 86 153 8.63E-18 T 28-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal CIG75_RS10420 506eedba69e9971163ac568ca1e4518c 323 Gene3D G3DSA:3.40.800.10 7 323 1.4E-72 T 28-03-2018 CIG75_RS10420 506eedba69e9971163ac568ca1e4518c 323 Pfam PF00491 Arginase family 39 313 1.9E-67 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 CIG75_RS10420 506eedba69e9971163ac568ca1e4518c 323 PIRSF PIRSF036979 13 321 3.8E-56 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 CIG75_RS10420 506eedba69e9971163ac568ca1e4518c 323 TIGRFAM TIGR01227 hutG: formimidoylglutamase 10 314 3.2E-70 T 28-03-2018 IPR005923 Formiminoglutamase GO:0019556|GO:0050415 KEGG: 00340+3.5.3.8 CIG75_RS10420 506eedba69e9971163ac568ca1e4518c 323 PRINTS PR00116 Arginase signature 125 140 2.9E-5 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 CIG75_RS10420 506eedba69e9971163ac568ca1e4518c 323 PRINTS PR00116 Arginase signature 241 270 2.9E-5 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 CIG75_RS10420 506eedba69e9971163ac568ca1e4518c 323 SUPERFAMILY SSF52768 28 316 9.36E-72 T 28-03-2018 CIG75_RS10420 506eedba69e9971163ac568ca1e4518c 323 ProSitePatterns PS01053 Arginase family signature. 244 265 - T 28-03-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 CIG75_RS18470 b19da94dcd7dc7ea743b29a0f0142805 679 Gene3D G3DSA:1.20.5.320 158 252 0.0083 T 28-03-2018 CIG75_RS18470 b19da94dcd7dc7ea743b29a0f0142805 679 Gene3D G3DSA:2.60.120.260 542 672 5.1E-17 T 28-03-2018 IPR008979 Galactose-binding domain-like CIG75_RS18470 b19da94dcd7dc7ea743b29a0f0142805 679 Gene3D G3DSA:1.20.5.50 103 132 0.0013 T 28-03-2018 CIG75_RS18470 b19da94dcd7dc7ea743b29a0f0142805 679 Gene3D G3DSA:1.20.5.50 133 157 9.0E-5 T 28-03-2018 CIG75_RS18470 b19da94dcd7dc7ea743b29a0f0142805 679 Gene3D G3DSA:1.20.5.50 254 289 0.34 T 28-03-2018 CIG75_RS18470 b19da94dcd7dc7ea743b29a0f0142805 679 Gene3D G3DSA:1.20.5.50 61 102 0.0016 T 28-03-2018 CIG75_RS18470 b19da94dcd7dc7ea743b29a0f0142805 679 Gene3D G3DSA:1.20.5.1070 474 515 0.0011 T 28-03-2018 CIG75_RS18470 b19da94dcd7dc7ea743b29a0f0142805 679 Gene3D G3DSA:1.20.5.50 367 473 2.8E-6 T 28-03-2018 CIG75_RS18470 b19da94dcd7dc7ea743b29a0f0142805 679 SUPERFAMILY SSF57997 37 232 5.3E-7 T 28-03-2018 CIG75_RS18470 b19da94dcd7dc7ea743b29a0f0142805 679 Gene3D G3DSA:1.20.5.730 290 366 0.36 T 28-03-2018 CIG75_RS10370 89b5875e70de6abc8f3ea9aa5f444aeb 141 Pfam PF07681 DoxX 9 86 6.4E-19 T 28-03-2018 IPR032808 DoxX family CIG75_RS01095 37595176d791a7fe07d42f351e386708 1722 SUPERFAMILY SSF110296 101 304 1.94E-11 T 28-03-2018 CIG75_RS01095 37595176d791a7fe07d42f351e386708 1722 Pfam PF00395 S-layer homology domain 1627 1668 5.0E-12 T 28-03-2018 IPR001119 S-layer homology domain CIG75_RS01095 37595176d791a7fe07d42f351e386708 1722 Pfam PF00395 S-layer homology domain 1530 1550 1.9E-6 T 28-03-2018 IPR001119 S-layer homology domain CIG75_RS01095 37595176d791a7fe07d42f351e386708 1722 Pfam PF00395 S-layer homology domain 1568 1610 3.3E-14 T 28-03-2018 IPR001119 S-layer homology domain CIG75_RS01095 37595176d791a7fe07d42f351e386708 1722 Pfam PF12733 Cadherin-like beta sandwich domain 928 1014 1.3E-14 T 28-03-2018 IPR025883 Cadherin-like beta sandwich domain CIG75_RS01095 37595176d791a7fe07d42f351e386708 1722 Pfam PF12733 Cadherin-like beta sandwich domain 335 427 2.2E-14 T 28-03-2018 IPR025883 Cadherin-like beta sandwich domain CIG75_RS01095 37595176d791a7fe07d42f351e386708 1722 Pfam PF12733 Cadherin-like beta sandwich domain 1026 1112 3.1E-14 T 28-03-2018 IPR025883 Cadherin-like beta sandwich domain CIG75_RS01095 37595176d791a7fe07d42f351e386708 1722 Pfam PF12733 Cadherin-like beta sandwich domain 830 916 1.3E-14 T 28-03-2018 IPR025883 Cadherin-like beta sandwich domain CIG75_RS01095 37595176d791a7fe07d42f351e386708 1722 Pfam PF12733 Cadherin-like beta sandwich domain 729 818 3.4E-15 T 28-03-2018 IPR025883 Cadherin-like beta sandwich domain CIG75_RS01095 37595176d791a7fe07d42f351e386708 1722 Pfam PF12733 Cadherin-like beta sandwich domain 631 720 3.4E-15 T 28-03-2018 IPR025883 Cadherin-like beta sandwich domain CIG75_RS01095 37595176d791a7fe07d42f351e386708 1722 Pfam PF12733 Cadherin-like beta sandwich domain 1121 1210 1.3E-15 T 28-03-2018 IPR025883 Cadherin-like beta sandwich domain CIG75_RS01095 37595176d791a7fe07d42f351e386708 1722 Pfam PF12733 Cadherin-like beta sandwich domain 1219 1309 4.0E-16 T 28-03-2018 IPR025883 Cadherin-like beta sandwich domain CIG75_RS01095 37595176d791a7fe07d42f351e386708 1722 Pfam PF12733 Cadherin-like beta sandwich domain 435 523 4.5E-16 T 28-03-2018 IPR025883 Cadherin-like beta sandwich domain CIG75_RS01095 37595176d791a7fe07d42f351e386708 1722 Pfam PF12733 Cadherin-like beta sandwich domain 536 622 1.3E-14 T 28-03-2018 IPR025883 Cadherin-like beta sandwich domain CIG75_RS01095 37595176d791a7fe07d42f351e386708 1722 Gene3D G3DSA:2.60.120.260 443 611 0.014 T 28-03-2018 IPR008979 Galactose-binding domain-like CIG75_RS01095 37595176d791a7fe07d42f351e386708 1722 Gene3D G3DSA:2.60.120.260 612 709 0.033 T 28-03-2018 IPR008979 Galactose-binding domain-like CIG75_RS01095 37595176d791a7fe07d42f351e386708 1722 Gene3D G3DSA:2.60.120.260 710 806 0.029 T 28-03-2018 IPR008979 Galactose-binding domain-like CIG75_RS01095 37595176d791a7fe07d42f351e386708 1722 Gene3D G3DSA:2.60.120.260 905 1002 0.042 T 28-03-2018 IPR008979 Galactose-binding domain-like CIG75_RS01095 37595176d791a7fe07d42f351e386708 1722 Gene3D G3DSA:2.60.120.260 807 904 0.047 T 28-03-2018 IPR008979 Galactose-binding domain-like CIG75_RS01095 37595176d791a7fe07d42f351e386708 1722 Gene3D G3DSA:2.60.120.260 1003 1100 0.11 T 28-03-2018 IPR008979 Galactose-binding domain-like CIG75_RS01095 37595176d791a7fe07d42f351e386708 1722 Gene3D G3DSA:2.60.120.260 1101 1202 0.026 T 28-03-2018 IPR008979 Galactose-binding domain-like CIG75_RS01095 37595176d791a7fe07d42f351e386708 1722 Gene3D G3DSA:2.60.40.1120 1412 1528 1.8E-7 T 28-03-2018 CIG75_RS01095 37595176d791a7fe07d42f351e386708 1722 Gene3D G3DSA:2.60.40.1120 1320 1410 0.0073 T 28-03-2018 CIG75_RS01095 37595176d791a7fe07d42f351e386708 1722 Gene3D G3DSA:2.130.10.10 100 402 2.4E-10 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CIG75_RS17125 9a301db11c460366e819c2d8d800826f 242 Gene3D G3DSA:3.40.30.10 67 242 1.8E-42 T 28-03-2018 CIG75_RS17125 9a301db11c460366e819c2d8d800826f 242 Pfam PF13462 Thioredoxin 71 234 6.9E-33 T 28-03-2018 IPR012336 Thioredoxin-like fold CIG75_RS17125 9a301db11c460366e819c2d8d800826f 242 SUPERFAMILY SSF52833 62 233 4.65E-46 T 28-03-2018 IPR012336 Thioredoxin-like fold CIG75_RS16115 db5f8aa9404faa8d9609ac94c1d6513b 315 PIRSF PIRSF005355 12 312 1.4E-80 T 28-03-2018 IPR026046 UbiA prenyltransferase domain containing protein 1 GO:0004659 Reactome: R-HSA-6806664 CIG75_RS16115 db5f8aa9404faa8d9609ac94c1d6513b 315 TIGRFAM TIGR00751 menA: 1,4-dihydroxy-2-naphthoate octaprenyltransferase 36 303 6.1E-41 T 28-03-2018 CIG75_RS16115 db5f8aa9404faa8d9609ac94c1d6513b 315 Hamap MF_01937 1,4-dihydroxy-2-naphthoate octaprenyltransferase [menA]. 20 307 18.487 T 28-03-2018 IPR004657 1,4-dihydroxy-2-naphthoate octaprenyltransferase GO:0009234|GO:0016021|GO:0046428 KEGG: 00130+2.5.1.74|MetaCyc: PWY-5839|MetaCyc: PWY-5851|MetaCyc: PWY-5852|MetaCyc: PWY-5853|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 CIG75_RS16115 db5f8aa9404faa8d9609ac94c1d6513b 315 Pfam PF01040 UbiA prenyltransferase family 37 279 3.6E-41 T 28-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 CIG75_RS02680 01dfe2c3a6c4345237987d42351e1dd0 427 Gene3D G3DSA:1.20.1250.20 2 208 3.2E-22 T 28-03-2018 CIG75_RS02680 01dfe2c3a6c4345237987d42351e1dd0 427 Gene3D G3DSA:1.20.1250.20 209 412 1.0E-11 T 28-03-2018 CIG75_RS02680 01dfe2c3a6c4345237987d42351e1dd0 427 PRINTS PR01035 Tetracycline resistance protein signature 142 164 2.5E-7 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CIG75_RS02680 01dfe2c3a6c4345237987d42351e1dd0 427 PRINTS PR01035 Tetracycline resistance protein signature 319 339 2.5E-7 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CIG75_RS02680 01dfe2c3a6c4345237987d42351e1dd0 427 PRINTS PR01035 Tetracycline resistance protein signature 53 72 2.5E-7 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CIG75_RS02680 01dfe2c3a6c4345237987d42351e1dd0 427 PRINTS PR01035 Tetracycline resistance protein signature 354 377 2.5E-7 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CIG75_RS02680 01dfe2c3a6c4345237987d42351e1dd0 427 PRINTS PR01035 Tetracycline resistance protein signature 85 109 2.5E-7 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CIG75_RS02680 01dfe2c3a6c4345237987d42351e1dd0 427 SUPERFAMILY SSF103473 15 407 1.11E-40 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS02680 01dfe2c3a6c4345237987d42351e1dd0 427 Pfam PF07690 Major Facilitator Superfamily 35 370 5.9E-34 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CIG75_RS10900 7ed3251a6f379b5dff6663cf46d669df 264 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 52 70 - T 28-03-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 CIG75_RS10900 7ed3251a6f379b5dff6663cf46d669df 264 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 1 258 35.328 T 28-03-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 CIG75_RS10900 7ed3251a6f379b5dff6663cf46d669df 264 SUPERFAMILY SSF51366 10 247 1.79E-85 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CIG75_RS10900 7ed3251a6f379b5dff6663cf46d669df 264 Gene3D G3DSA:3.20.20.70 3 259 1.1E-72 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CIG75_RS10900 7ed3251a6f379b5dff6663cf46d669df 264 Pfam PF00218 Indole-3-glycerol phosphate synthase 3 247 1.7E-94 T 28-03-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 CIG75_RS04990 c4ec9d77b2bf1e575a2ed46f5de27036 214 SUPERFAMILY SSF52266 4 213 4.5E-25 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CIG75_RS04990 c4ec9d77b2bf1e575a2ed46f5de27036 214 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 6 203 1.9E-24 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CIG75_RS04990 c4ec9d77b2bf1e575a2ed46f5de27036 214 Gene3D G3DSA:3.40.50.1110 3 214 2.4E-27 T 28-03-2018 CIG75_RS01005 56403e12a395a09ce197bceb03d9fea7 341 Gene3D G3DSA:3.40.50.720 3 170 7.9E-32 T 28-03-2018 CIG75_RS01005 56403e12a395a09ce197bceb03d9fea7 341 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 9 331 3.1E-125 T 28-03-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-70370 CIG75_RS01005 56403e12a395a09ce197bceb03d9fea7 341 Pfam PF01370 NAD dependent epimerase/dehydratase family 9 258 4.8E-55 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CIG75_RS01005 56403e12a395a09ce197bceb03d9fea7 341 Gene3D G3DSA:3.90.25.10 171 339 7.8E-38 T 28-03-2018 CIG75_RS01005 56403e12a395a09ce197bceb03d9fea7 341 SUPERFAMILY SSF51735 8 333 1.72E-85 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS06845 ae4410404cd14605f08dc723efda9878 504 Pfam PF04055 Radical SAM superfamily 181 354 5.3E-20 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CIG75_RS06845 ae4410404cd14605f08dc723efda9878 504 SMART SM00729 173 397 1.7E-47 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CIG75_RS06845 ae4410404cd14605f08dc723efda9878 504 TIGRFAM TIGR03994 rSAM_HemZ: coproporphyrinogen dehydrogenase HemZ 91 488 1.8E-143 T 28-03-2018 IPR023995 Oxygen-independent coproporphyrinogen-III oxidase-like protein HemZ CIG75_RS06845 ae4410404cd14605f08dc723efda9878 504 SUPERFAMILY SSF102114 169 483 3.53E-67 T 28-03-2018 CIG75_RS06845 ae4410404cd14605f08dc723efda9878 504 Gene3D G3DSA:3.20.20.70 84 491 2.9E-44 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CIG75_RS14050 0f59ce53fa22b3bd16f65383c59c6681 340 PIRSF PIRSF000149 1 335 5.0E-138 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS14050 0f59ce53fa22b3bd16f65383c59c6681 340 SUPERFAMILY SSF51735 3 168 2.92E-62 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS14050 0f59ce53fa22b3bd16f65383c59c6681 340 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 229 246 4.5E-42 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS14050 0f59ce53fa22b3bd16f65383c59c6681 340 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 109 122 4.5E-42 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS14050 0f59ce53fa22b3bd16f65383c59c6681 340 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 269 284 4.5E-42 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS14050 0f59ce53fa22b3bd16f65383c59c6681 340 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 173 189 4.5E-42 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS14050 0f59ce53fa22b3bd16f65383c59c6681 340 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 146 164 4.5E-42 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS14050 0f59ce53fa22b3bd16f65383c59c6681 340 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 157 313 5.1E-69 T 28-03-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS14050 0f59ce53fa22b3bd16f65383c59c6681 340 Gene3D G3DSA:3.40.50.720 1 161 7.8E-77 T 28-03-2018 CIG75_RS14050 0f59ce53fa22b3bd16f65383c59c6681 340 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 325 5.5E-139 T 28-03-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS14050 0f59ce53fa22b3bd16f65383c59c6681 340 Gene3D G3DSA:3.30.360.10 162 315 4.7E-70 T 28-03-2018 CIG75_RS14050 0f59ce53fa22b3bd16f65383c59c6681 340 SMART SM00846 3 152 8.8E-91 T 28-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS14050 0f59ce53fa22b3bd16f65383c59c6681 340 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 150 157 - T 28-03-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS14050 0f59ce53fa22b3bd16f65383c59c6681 340 SUPERFAMILY SSF55347 152 314 6.55E-75 T 28-03-2018 CIG75_RS14050 0f59ce53fa22b3bd16f65383c59c6681 340 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 102 1.9E-37 T 28-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS03355 193d3a23a609353f5b1de165408046ae 448 Gene3D G3DSA:1.20.1250.20 248 445 1.8E-16 T 28-03-2018 CIG75_RS03355 193d3a23a609353f5b1de165408046ae 448 Gene3D G3DSA:1.20.1250.20 38 228 1.8E-13 T 28-03-2018 CIG75_RS03355 193d3a23a609353f5b1de165408046ae 448 Pfam PF05977 Transmembrane secretion effector 48 434 5.6E-21 T 28-03-2018 IPR010290 Transmembrane secretion effector CIG75_RS03355 193d3a23a609353f5b1de165408046ae 448 SUPERFAMILY SSF103473 51 438 7.85E-39 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS07410 8e1d477484011fe3a1b5c0f62e6eae54 150 Gene3D G3DSA:1.10.10.10 1 150 1.5E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS07410 8e1d477484011fe3a1b5c0f62e6eae54 150 SUPERFAMILY SSF46785 2 138 2.72E-36 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS07410 8e1d477484011fe3a1b5c0f62e6eae54 150 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 28-03-2018 IPR030489 Transcription regulator Rrf2-type, conserved site CIG75_RS07410 8e1d477484011fe3a1b5c0f62e6eae54 150 Pfam PF02082 Transcriptional regulator 1 82 2.2E-29 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type CIG75_RS07410 8e1d477484011fe3a1b5c0f62e6eae54 150 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 2 136 1.2E-42 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type CIG75_RS08975 df939c7ca4ef56539f43233f281912b0 80 Pfam PF07293 Protein of unknown function (DUF1450) 4 74 3.7E-18 T 28-03-2018 IPR009910 Protein of unknown function DUF1450 CIG75_RS08975 df939c7ca4ef56539f43233f281912b0 80 ProDom PD058324 UPF0349 LMO2392 BLI03401/BL03152 SA0800 SAR0901 LIN2491 SERP0525 GK2958 BT9727_4649 BC4937 5 67 3.0E-8 T 28-03-2018 CIG75_RS11790 79a3a2a6fef27414a5714e0c05d63b07 337 Pfam PF01368 DHH family 26 163 5.3E-13 T 28-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CIG75_RS11790 79a3a2a6fef27414a5714e0c05d63b07 337 SUPERFAMILY SSF64182 21 309 9.81E-59 T 28-03-2018 CIG75_RS11790 79a3a2a6fef27414a5714e0c05d63b07 337 Pfam PF02272 DHHA1 domain 247 319 3.5E-9 T 28-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CIG75_RS11790 79a3a2a6fef27414a5714e0c05d63b07 337 Gene3D G3DSA:3.90.1640.10 2 205 4.8E-40 T 28-03-2018 CIG75_RS11410 999fe1ef30733510bb17833b5ec43256 254 Pfam PF00032 Cytochrome b(C-terminal)/b6/petD 74 152 5.6E-12 T 28-03-2018 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 CIG75_RS11410 999fe1ef30733510bb17833b5ec43256 254 SUPERFAMILY SSF81648 17 152 1.57E-28 T 28-03-2018 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 CIG75_RS11410 999fe1ef30733510bb17833b5ec43256 254 Gene3D G3DSA:1.10.760.10 152 254 1.7E-16 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CIG75_RS11410 999fe1ef30733510bb17833b5ec43256 254 SUPERFAMILY SSF46626 132 251 9.17E-21 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CIG75_RS11410 999fe1ef30733510bb17833b5ec43256 254 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 177 248 4.7E-13 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CIG75_RS11410 999fe1ef30733510bb17833b5ec43256 254 Gene3D G3DSA:1.20.810.10 10 151 1.0E-29 T 28-03-2018 IPR027387 Cytochrome b/b6-like domain Reactome: R-HSA-611105 CIG75_RS03670 ef3ad09b205dadcac0a2ac7db0069067 345 SUPERFAMILY SSF50156 92 187 5.26E-14 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CIG75_RS03670 ef3ad09b205dadcac0a2ac7db0069067 345 Gene3D G3DSA:2.30.42.10 116 212 1.8E-16 T 28-03-2018 CIG75_RS03670 ef3ad09b205dadcac0a2ac7db0069067 345 Pfam PF13180 PDZ domain 121 186 1.6E-7 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CIG75_RS03670 ef3ad09b205dadcac0a2ac7db0069067 345 Pfam PF02163 Peptidase family M50 6 330 1.8E-70 T 28-03-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889|Reactome: R-MMU-8963889 CIG75_RS03670 ef3ad09b205dadcac0a2ac7db0069067 345 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 119 342 1.1E-49 T 28-03-2018 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 CIG75_RS11545 47922cf57ec415f8ffddd558224bc2bb 276 SUPERFAMILY SSF89550 163 250 7.59E-46 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CIG75_RS11545 47922cf57ec415f8ffddd558224bc2bb 276 SUPERFAMILY SSF89550 3 82 7.59E-46 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CIG75_RS11545 47922cf57ec415f8ffddd558224bc2bb 276 SMART SM00481 4 69 1.0E-22 T 28-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal CIG75_RS11545 47922cf57ec415f8ffddd558224bc2bb 276 Gene3D G3DSA:3.20.20.140 1 252 1.8E-50 T 28-03-2018 CIG75_RS11545 47922cf57ec415f8ffddd558224bc2bb 276 Pfam PF02811 PHP domain 5 130 2.9E-11 T 28-03-2018 IPR004013 PHP domain GO:0003824 CIG75_RS12225 5b263ceaf95f875c01210265e73dc491 115 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 5 114 5.4E-50 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS12225 5b263ceaf95f875c01210265e73dc491 115 PRINTS PR00061 Ribosomal protein L19 signature 35 64 1.2E-41 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS12225 5b263ceaf95f875c01210265e73dc491 115 PRINTS PR00061 Ribosomal protein L19 signature 5 34 1.2E-41 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS12225 5b263ceaf95f875c01210265e73dc491 115 PRINTS PR00061 Ribosomal protein L19 signature 89 114 1.2E-41 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS12225 5b263ceaf95f875c01210265e73dc491 115 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 3 115 32.515 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS12225 5b263ceaf95f875c01210265e73dc491 115 Pfam PF01245 Ribosomal protein L19 6 113 2.7E-52 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS12225 5b263ceaf95f875c01210265e73dc491 115 SUPERFAMILY SSF50104 7 114 4.61E-47 T 28-03-2018 IPR008991 Translation protein SH3-like domain CIG75_RS12225 5b263ceaf95f875c01210265e73dc491 115 ProSitePatterns PS01015 Ribosomal protein L19 signature. 87 102 - T 28-03-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS12225 5b263ceaf95f875c01210265e73dc491 115 PIRSF PIRSF002191 1 115 5.5E-51 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS15155 24fb6f42e9ca226997f7928775a8bcd6 376 TIGRFAM TIGR02352 thiamin_ThiO: glycine oxidase ThiO 11 359 8.7E-91 T 28-03-2018 IPR012727 Glycine oxidase ThiO GO:0016491|GO:0050660 CIG75_RS15155 24fb6f42e9ca226997f7928775a8bcd6 376 Gene3D G3DSA:3.30.9.10 200 315 7.2E-30 T 28-03-2018 CIG75_RS15155 24fb6f42e9ca226997f7928775a8bcd6 376 Gene3D G3DSA:3.50.50.60 4 199 1.3E-18 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS15155 24fb6f42e9ca226997f7928775a8bcd6 376 Pfam PF01266 FAD dependent oxidoreductase 9 355 2.1E-69 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CIG75_RS15155 24fb6f42e9ca226997f7928775a8bcd6 376 SUPERFAMILY SSF54373 228 314 3.14E-16 T 28-03-2018 CIG75_RS15155 24fb6f42e9ca226997f7928775a8bcd6 376 SUPERFAMILY SSF51905 8 228 2.59E-54 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS15155 24fb6f42e9ca226997f7928775a8bcd6 376 SUPERFAMILY SSF51905 316 373 2.59E-54 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS19285 bc9bafbaa3a42cb42252e75504513e40 423 Gene3D G3DSA:1.10.150.130 105 216 3.2E-18 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CIG75_RS19285 bc9bafbaa3a42cb42252e75504513e40 423 Pfam PF00589 Phage integrase family 214 400 2.7E-30 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CIG75_RS19285 bc9bafbaa3a42cb42252e75504513e40 423 SUPERFAMILY SSF56349 107 403 1.53E-66 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CIG75_RS19285 bc9bafbaa3a42cb42252e75504513e40 423 Gene3D G3DSA:1.10.443.10 217 407 9.6E-43 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CIG75_RS02020 521eb53ec8bbf3dd0d236c258c30f4e8 436 SUPERFAMILY SSF55205 1 420 2.09E-133 T 28-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CIG75_RS02020 521eb53ec8bbf3dd0d236c258c30f4e8 436 Gene3D G3DSA:3.65.10.10 224 421 6.0E-49 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CIG75_RS02020 521eb53ec8bbf3dd0d236c258c30f4e8 436 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 6 408 4.9E-100 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CIG75_RS02020 521eb53ec8bbf3dd0d236c258c30f4e8 436 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 418 1.8E-168 T 28-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CIG75_RS02020 521eb53ec8bbf3dd0d236c258c30f4e8 436 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 419 44.186 T 28-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CIG75_RS02020 521eb53ec8bbf3dd0d236c258c30f4e8 436 Gene3D G3DSA:3.65.10.10 21 223 7.0E-44 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CIG75_RS18060 1b2b0a6c0ab9bf76234bf7d0508086cc 407 Gene3D G3DSA:1.20.1250.20 2 201 1.4E-10 T 28-03-2018 CIG75_RS18060 1b2b0a6c0ab9bf76234bf7d0508086cc 407 SUPERFAMILY SSF103473 7 403 2.75E-30 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS18060 1b2b0a6c0ab9bf76234bf7d0508086cc 407 Pfam PF07690 Major Facilitator Superfamily 11 326 6.0E-12 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CIG75_RS18060 1b2b0a6c0ab9bf76234bf7d0508086cc 407 Gene3D G3DSA:1.20.1250.20 205 398 4.4E-15 T 28-03-2018 CIG75_RS14820 1993ca92db7396b50be6ff493f9e3fcf 516 Gene3D G3DSA:1.10.560.10 1 214 8.0E-42 T 28-03-2018 IPR027413 GroEL-like equatorial domain CIG75_RS14820 1993ca92db7396b50be6ff493f9e3fcf 516 Gene3D G3DSA:1.10.560.10 354 509 7.6E-29 T 28-03-2018 IPR027413 GroEL-like equatorial domain CIG75_RS14820 1993ca92db7396b50be6ff493f9e3fcf 516 ProSitePatterns PS00751 Chaperonins TCP-1 signature 2. 56 72 - T 28-03-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 CIG75_RS14820 1993ca92db7396b50be6ff493f9e3fcf 516 Gene3D G3DSA:3.50.7.10 215 353 2.8E-20 T 28-03-2018 IPR027409 GroEL-like apical domain CIG75_RS14820 1993ca92db7396b50be6ff493f9e3fcf 516 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 32 48 1.1E-29 T 28-03-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 CIG75_RS14820 1993ca92db7396b50be6ff493f9e3fcf 516 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 357 379 1.1E-29 T 28-03-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 CIG75_RS14820 1993ca92db7396b50be6ff493f9e3fcf 516 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 84 103 1.1E-29 T 28-03-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 CIG75_RS14820 1993ca92db7396b50be6ff493f9e3fcf 516 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 390 402 1.1E-29 T 28-03-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 CIG75_RS14820 1993ca92db7396b50be6ff493f9e3fcf 516 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 54 72 1.1E-29 T 28-03-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 CIG75_RS14820 1993ca92db7396b50be6ff493f9e3fcf 516 Pfam PF00118 TCP-1/cpn60 chaperonin family 30 509 1.1E-104 T 28-03-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 CIG75_RS14820 1993ca92db7396b50be6ff493f9e3fcf 516 SUPERFAMILY SSF48592 387 508 4.97E-66 T 28-03-2018 CIG75_RS14820 1993ca92db7396b50be6ff493f9e3fcf 516 SUPERFAMILY SSF48592 16 139 4.97E-66 T 28-03-2018 CIG75_RS14820 1993ca92db7396b50be6ff493f9e3fcf 516 SUPERFAMILY SSF52029 197 360 1.28E-21 T 28-03-2018 IPR027409 GroEL-like apical domain CIG75_RS12665 cf341eee2ac6110a72114f01f85c0c0c 414 Pfam PF00665 Integrase core domain 115 241 4.8E-26 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CIG75_RS12665 cf341eee2ac6110a72114f01f85c0c0c 414 Pfam PF13936 Helix-turn-helix domain 12 39 1.1E-6 T 28-03-2018 IPR025246 Transposase IS30-like HTH domain CIG75_RS12665 cf341eee2ac6110a72114f01f85c0c0c 414 Gene3D G3DSA:1.10.10.60 8 44 2.8E-11 T 28-03-2018 CIG75_RS12665 cf341eee2ac6110a72114f01f85c0c0c 414 Gene3D G3DSA:3.30.420.10 109 364 8.4E-28 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CIG75_RS12665 cf341eee2ac6110a72114f01f85c0c0c 414 SUPERFAMILY SSF53098 116 286 1.1E-15 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CIG75_RS16535 d8a5e16e173cdf731d2c13cf6cd6119e 369 Gene3D G3DSA:3.40.1830.10 2 163 5.7E-41 T 28-03-2018 IPR035097 Peptidase M29, N-terminal CIG75_RS16535 d8a5e16e173cdf731d2c13cf6cd6119e 369 Pfam PF02073 Thermophilic metalloprotease (M29) 3 336 1.1E-57 T 28-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CIG75_RS16535 d8a5e16e173cdf731d2c13cf6cd6119e 369 SUPERFAMILY SSF144052 1 357 6.15E-104 T 28-03-2018 CIG75_RS02900 afa66ea0470debbaced947bdf443ef45 105 SUPERFAMILY SSF47240 8 59 1.21E-6 T 28-03-2018 IPR009078 Ferritin-like superfamily CIG75_RS02900 afa66ea0470debbaced947bdf443ef45 105 Gene3D G3DSA:1.20.1260.10 1 62 3.7E-6 T 28-03-2018 IPR012347 Ferritin-related CIG75_RS04840 484586137c256af22c6237de2e2938ca 303 SUPERFAMILY SSF48452 105 287 1.44E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS04840 484586137c256af22c6237de2e2938ca 303 SMART SM00028 222 255 120.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS04840 484586137c256af22c6237de2e2938ca 303 SMART SM00028 184 217 230.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS04840 484586137c256af22c6237de2e2938ca 303 SMART SM00028 104 137 0.062 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS04840 484586137c256af22c6237de2e2938ca 303 SMART SM00028 66 99 0.023 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS04840 484586137c256af22c6237de2e2938ca 303 Gene3D G3DSA:1.25.40.10 80 119 7.0E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS04840 484586137c256af22c6237de2e2938ca 303 Gene3D G3DSA:1.25.40.10 120 168 0.0052 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS04840 484586137c256af22c6237de2e2938ca 303 Gene3D G3DSA:1.25.40.10 1 79 2.6E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS04840 484586137c256af22c6237de2e2938ca 303 Pfam PF13181 Tetratricopeptide repeat 67 99 1.2E-4 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS04840 484586137c256af22c6237de2e2938ca 303 Pfam PF13181 Tetratricopeptide repeat 105 130 0.0078 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS04840 484586137c256af22c6237de2e2938ca 303 Gene3D G3DSA:1.25.40.10 169 287 6.9E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS04840 484586137c256af22c6237de2e2938ca 303 SUPERFAMILY SSF48452 2 150 5.06E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS14410 9dacf49bea4d71e4d062bb19c38ba331 219 Pfam PF01144 Coenzyme A transferase 7 200 3.8E-44 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CIG75_RS14410 9dacf49bea4d71e4d062bb19c38ba331 219 SMART SM00882 6 202 1.4E-80 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CIG75_RS14410 9dacf49bea4d71e4d062bb19c38ba331 219 SUPERFAMILY SSF100950 4 211 1.91E-76 T 28-03-2018 CIG75_RS14410 9dacf49bea4d71e4d062bb19c38ba331 219 ProSitePatterns PS01274 Coenzyme A transferases signature 2. 44 52 - T 28-03-2018 IPR004164 Coenzyme A transferase active site GO:0008152|GO:0008410 Reactome: R-HSA-77108 CIG75_RS14410 9dacf49bea4d71e4d062bb19c38ba331 219 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 4 208 9.2E-102 T 28-03-2018 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 Reactome: R-HSA-77108 CIG75_RS14410 9dacf49bea4d71e4d062bb19c38ba331 219 Gene3D G3DSA:3.40.1080.10 3 214 2.4E-73 T 28-03-2018 CIG75_RS09140 c0a4522317c0d41db1c09d2b0154143a 290 SUPERFAMILY SSF51412 4 272 1.33E-59 T 28-03-2018 CIG75_RS09140 c0a4522317c0d41db1c09d2b0154143a 290 Pfam PF03060 Nitronate monooxygenase 5 73 4.2E-15 T 28-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 CIG75_RS09140 c0a4522317c0d41db1c09d2b0154143a 290 Pfam PF03060 Nitronate monooxygenase 81 247 1.0E-42 T 28-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 CIG75_RS09140 c0a4522317c0d41db1c09d2b0154143a 290 Gene3D G3DSA:3.20.20.70 1 272 7.1E-49 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CIG75_RS12085 2a4a10f3e7b3d62be2824ba4211c2fa5 255 Hamap MF_00621 GTP-sensing transcriptional pleiotropic repressor CodY [codY]. 1 255 92.854 T 28-03-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 CIG75_RS12085 2a4a10f3e7b3d62be2824ba4211c2fa5 255 Gene3D G3DSA:3.30.450.40 1 155 7.9E-15 T 28-03-2018 IPR029016 GAF domain-like CIG75_RS12085 2a4a10f3e7b3d62be2824ba4211c2fa5 255 SUPERFAMILY SSF46785 163 251 1.23E-37 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS12085 2a4a10f3e7b3d62be2824ba4211c2fa5 255 Pfam PF06018 CodY GAF-like domain 2 174 3.2E-38 T 28-03-2018 IPR010312 GTP-sensing transcriptional pleiotropic repressor CodY, N-terminal GO:0003677|GO:0005525 CIG75_RS12085 2a4a10f3e7b3d62be2824ba4211c2fa5 255 Pfam PF08222 CodY helix-turn-helix domain 194 253 1.3E-32 T 28-03-2018 IPR013198 GTP-sensing helix-turn-helix, CodY, C-terminal CIG75_RS12085 2a4a10f3e7b3d62be2824ba4211c2fa5 255 TIGRFAM TIGR02787 codY_Gpos: GTP-sensing transcriptional pleiotropic repressor CodY 3 246 1.3E-83 T 28-03-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 CIG75_RS12085 2a4a10f3e7b3d62be2824ba4211c2fa5 255 Gene3D G3DSA:1.10.10.10 156 255 1.7E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS12085 2a4a10f3e7b3d62be2824ba4211c2fa5 255 PIRSF PIRSF011572 1 253 2.4E-87 T 28-03-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 CIG75_RS11795 7d4ae0ec8d83a4d180078189d9309b90 122 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 1 115 24.18 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 CIG75_RS11795 7d4ae0ec8d83a4d180078189d9309b90 122 Pfam PF02033 Ribosome-binding factor A 5 108 1.2E-34 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 CIG75_RS11795 7d4ae0ec8d83a4d180078189d9309b90 122 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 8 95 4.0E-23 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 CIG75_RS11795 7d4ae0ec8d83a4d180078189d9309b90 122 SUPERFAMILY SSF89919 2 111 3.01E-37 T 28-03-2018 IPR023799 Ribosome-binding factor A domain CIG75_RS11795 7d4ae0ec8d83a4d180078189d9309b90 122 ProSitePatterns PS01319 Ribosome-binding factor A signature. 74 95 - T 28-03-2018 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 CIG75_RS11795 7d4ae0ec8d83a4d180078189d9309b90 122 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 1 113 1.9E-39 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 CIG75_RS11795 7d4ae0ec8d83a4d180078189d9309b90 122 Gene3D G3DSA:3.30.300.20 3 115 2.4E-36 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CIG75_RS12950 d24c3e9e17f9d7b0a5e100210017e989 65 SMART SM00530 8 62 4.9E-10 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS12950 d24c3e9e17f9d7b0a5e100210017e989 65 Pfam PF01381 Helix-turn-helix 9 62 1.0E-11 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS12950 d24c3e9e17f9d7b0a5e100210017e989 65 SUPERFAMILY SSF47413 6 63 3.38E-12 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CIG75_RS12950 d24c3e9e17f9d7b0a5e100210017e989 65 Gene3D G3DSA:1.10.3100.10 2 65 3.9E-12 T 28-03-2018 IPR027910 YdiL-like domain CIG75_RS05790 55223a105d8ac8395f259def1a2b52b3 403 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 182 224 5.2E-10 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CIG75_RS05790 55223a105d8ac8395f259def1a2b52b3 403 Gene3D G3DSA:3.30.980.10 87 241 1.9E-38 T 28-03-2018 CIG75_RS05790 55223a105d8ac8395f259def1a2b52b3 403 SUPERFAMILY SSF55186 90 230 1.83E-36 T 28-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 CIG75_RS05790 55223a105d8ac8395f259def1a2b52b3 403 Pfam PF01411 tRNA synthetases class II (A) 16 89 4.4E-8 T 28-03-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 CIG75_RS05790 55223a105d8ac8395f259def1a2b52b3 403 Pfam PF02272 DHHA1 domain 260 397 1.4E-11 T 28-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CIG75_RS05790 55223a105d8ac8395f259def1a2b52b3 403 SUPERFAMILY SSF50447 1 74 8.12E-18 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CIG75_RS05790 55223a105d8ac8395f259def1a2b52b3 403 SMART SM00863 182 224 7.2E-14 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CIG75_RS08905 64779834704a5ba3438e3fee1ef5429e 438 SUPERFAMILY SSF48452 179 356 3.89E-24 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS08905 64779834704a5ba3438e3fee1ef5429e 438 SUPERFAMILY SSF48452 335 428 1.83E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS08905 64779834704a5ba3438e3fee1ef5429e 438 Gene3D G3DSA:1.10.150.200 191 249 8.1E-4 T 28-03-2018 CIG75_RS08905 64779834704a5ba3438e3fee1ef5429e 438 Gene3D G3DSA:1.10.260.40 3 72 2.0E-12 T 28-03-2018 CIG75_RS08905 64779834704a5ba3438e3fee1ef5429e 438 SMART SM00530 16 70 7.5E-7 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS08905 64779834704a5ba3438e3fee1ef5429e 438 Pfam PF13424 Tetratricopeptide repeat 243 313 7.4E-10 T 28-03-2018 CIG75_RS08905 64779834704a5ba3438e3fee1ef5429e 438 SUPERFAMILY SSF47413 12 73 2.31E-11 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CIG75_RS08905 64779834704a5ba3438e3fee1ef5429e 438 Pfam PF13374 Tetratricopeptide repeat 322 353 0.0018 T 28-03-2018 CIG75_RS08905 64779834704a5ba3438e3fee1ef5429e 438 Gene3D G3DSA:1.25.40.10 250 278 1.8E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS08905 64779834704a5ba3438e3fee1ef5429e 438 Gene3D G3DSA:1.25.40.10 279 324 5.2E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS08905 64779834704a5ba3438e3fee1ef5429e 438 Pfam PF01381 Helix-turn-helix 17 70 3.7E-5 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS08905 64779834704a5ba3438e3fee1ef5429e 438 SMART SM00028 361 394 290.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS08905 64779834704a5ba3438e3fee1ef5429e 438 SMART SM00028 241 274 31.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS08905 64779834704a5ba3438e3fee1ef5429e 438 SMART SM00028 321 354 130.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS08905 64779834704a5ba3438e3fee1ef5429e 438 SMART SM00028 281 314 0.018 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS08905 64779834704a5ba3438e3fee1ef5429e 438 SMART SM00028 201 234 290.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS08905 64779834704a5ba3438e3fee1ef5429e 438 Gene3D G3DSA:1.25.40.10 325 438 2.2E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS08905 64779834704a5ba3438e3fee1ef5429e 438 Gene3D G3DSA:1.25.40.10 73 190 0.0038 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS05815 e81d25be92082221e3371a8cd9c61172 184 Gene3D G3DSA:3.40.630.30 1 184 1.1E-33 T 28-03-2018 CIG75_RS05815 e81d25be92082221e3371a8cd9c61172 184 SUPERFAMILY SSF55729 2 170 4.29E-40 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CIG75_RS05815 e81d25be92082221e3371a8cd9c61172 184 Pfam PF13302 Acetyltransferase (GNAT) domain 5 145 7.8E-19 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CIG75_RS17400 6040b52d4cc2b1a00aaf7c6ba9c67e1a 429 Gene3D G3DSA:2.30.42.10 296 381 9.9E-9 T 28-03-2018 CIG75_RS17400 6040b52d4cc2b1a00aaf7c6ba9c67e1a 429 SUPERFAMILY SSF50156 313 398 7.36E-13 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CIG75_RS13170 f55bea8d57a7c07fe889a8fe16fd5e80 924 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 30 636 3.6E-216 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CIG75_RS13170 f55bea8d57a7c07fe889a8fe16fd5e80 924 SUPERFAMILY SSF50677 206 397 3.66E-60 T 28-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CIG75_RS13170 f55bea8d57a7c07fe889a8fe16fd5e80 924 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 53 64 1.9E-32 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CIG75_RS13170 f55bea8d57a7c07fe889a8fe16fd5e80 924 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 232 255 1.9E-32 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CIG75_RS13170 f55bea8d57a7c07fe889a8fe16fd5e80 924 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 395 410 1.9E-32 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CIG75_RS13170 f55bea8d57a7c07fe889a8fe16fd5e80 924 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 557 566 1.9E-32 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CIG75_RS13170 f55bea8d57a7c07fe889a8fe16fd5e80 924 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 523 536 1.9E-32 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CIG75_RS13170 f55bea8d57a7c07fe889a8fe16fd5e80 924 Gene3D G3DSA:3.90.740.10 219 494 1.7E-100 T 28-03-2018 CIG75_RS13170 f55bea8d57a7c07fe889a8fe16fd5e80 924 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 60 71 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CIG75_RS13170 f55bea8d57a7c07fe889a8fe16fd5e80 924 Pfam PF08264 Anticodon-binding domain of tRNA 681 834 1.2E-22 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CIG75_RS13170 f55bea8d57a7c07fe889a8fe16fd5e80 924 SUPERFAMILY SSF47323 648 918 3.92E-65 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CIG75_RS13170 f55bea8d57a7c07fe889a8fe16fd5e80 924 Pfam PF06827 Zinc finger found in FPG and IleRS 889 916 4.7E-6 T 28-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 CIG75_RS13170 f55bea8d57a7c07fe889a8fe16fd5e80 924 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 16 836 0.0 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CIG75_RS13170 f55bea8d57a7c07fe889a8fe16fd5e80 924 Gene3D G3DSA:1.10.730.10 574 795 2.3E-46 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CIG75_RS13170 f55bea8d57a7c07fe889a8fe16fd5e80 924 Hamap MF_02002 Isoleucine--tRNA ligase [ileS]. 4 920 20.833 T 28-03-2018 IPR023585 Isoleucine-tRNA ligase, type 1 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-379726 CIG75_RS13170 f55bea8d57a7c07fe889a8fe16fd5e80 924 Gene3D G3DSA:3.40.50.620 49 218 9.9E-41 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CIG75_RS13170 f55bea8d57a7c07fe889a8fe16fd5e80 924 SUPERFAMILY SSF52374 397 644 5.16E-155 T 28-03-2018 CIG75_RS13170 f55bea8d57a7c07fe889a8fe16fd5e80 924 SUPERFAMILY SSF52374 6 204 5.16E-155 T 28-03-2018 CIG75_RS13170 f55bea8d57a7c07fe889a8fe16fd5e80 924 Gene3D G3DSA:3.30.2320.20 796 887 1.7E-21 T 28-03-2018 CIG75_RS04405 3f55cf566ebfb8b09842317f4f47b187 448 SUPERFAMILY SSF74853 28 130 4.05E-13 T 28-03-2018 IPR001322 Lamin Tail Domain CIG75_RS04405 3f55cf566ebfb8b09842317f4f47b187 448 Pfam PF00932 Lamin Tail Domain 29 129 9.9E-19 T 28-03-2018 IPR001322 Lamin Tail Domain CIG75_RS04405 3f55cf566ebfb8b09842317f4f47b187 448 Gene3D G3DSA:2.60.40.1260 30 136 1.7E-22 T 28-03-2018 IPR001322 Lamin Tail Domain CIG75_RS04405 3f55cf566ebfb8b09842317f4f47b187 448 Gene3D G3DSA:3.40.50.880 201 448 3.2E-30 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CIG75_RS04405 3f55cf566ebfb8b09842317f4f47b187 448 SUPERFAMILY SSF52317 205 447 1.05E-13 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CIG75_RS08315 5264cc0066d41f9e75dc76044f31207e 306 SUPERFAMILY SSF103481 207 300 9.55E-11 T 28-03-2018 CIG75_RS08315 5264cc0066d41f9e75dc76044f31207e 306 SUPERFAMILY SSF103481 46 153 3.66E-11 T 28-03-2018 CIG75_RS08315 5264cc0066d41f9e75dc76044f31207e 306 Pfam PF00892 EamA-like transporter family 162 296 1.4E-14 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CIG75_RS08315 5264cc0066d41f9e75dc76044f31207e 306 Pfam PF00892 EamA-like transporter family 10 150 9.4E-20 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CIG75_RS02965 52183ac949b0faf90250529851c203c6 186 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 3 25 4.3E-12 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CIG75_RS02965 52183ac949b0faf90250529851c203c6 186 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 98 106 4.3E-12 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CIG75_RS02965 52183ac949b0faf90250529851c203c6 186 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 53 63 4.3E-12 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CIG75_RS02965 52183ac949b0faf90250529851c203c6 186 SUPERFAMILY SSF51905 1 174 4.12E-30 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS02965 52183ac949b0faf90250529851c203c6 186 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 106 6.0E-9 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS02965 52183ac949b0faf90250529851c203c6 186 Gene3D G3DSA:3.50.50.60 1 177 1.3E-31 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS02965 52183ac949b0faf90250529851c203c6 186 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 1.4E-8 T 28-03-2018 CIG75_RS02965 52183ac949b0faf90250529851c203c6 186 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 97 115 1.4E-8 T 28-03-2018 CIG75_RS01275 f4859c266add40e382656e28165e18b3 332 Gene3D G3DSA:3.40.250.10 111 219 8.0E-28 T 28-03-2018 IPR001763 Rhodanese-like domain CIG75_RS01275 f4859c266add40e382656e28165e18b3 332 SUPERFAMILY SSF52821 90 243 1.44E-32 T 28-03-2018 IPR001763 Rhodanese-like domain CIG75_RS01275 f4859c266add40e382656e28165e18b3 332 Pfam PF12368 Rhodanase C-terminal 224 290 2.2E-17 T 28-03-2018 IPR022111 Rhodanase, C-terminal CIG75_RS01275 f4859c266add40e382656e28165e18b3 332 Hamap MF_00469 UPF0176 protein YceA [yceA]. 5 259 40.634 T 28-03-2018 IPR020936 Uncharacterised protein family UPF0176 CIG75_RS01275 f4859c266add40e382656e28165e18b3 332 Pfam PF00581 Rhodanese-like domain 120 214 1.0E-9 T 28-03-2018 IPR001763 Rhodanese-like domain CIG75_RS01275 f4859c266add40e382656e28165e18b3 332 SMART SM00450 117 218 7.3E-20 T 28-03-2018 IPR001763 Rhodanese-like domain CIG75_RS09250 f0c4df2393209f121d40f9e8423f6799 421 Gene3D G3DSA:1.20.1250.20 208 412 2.1E-16 T 28-03-2018 CIG75_RS09250 f0c4df2393209f121d40f9e8423f6799 421 Pfam PF07690 Major Facilitator Superfamily 19 368 5.9E-26 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CIG75_RS09250 f0c4df2393209f121d40f9e8423f6799 421 Gene3D G3DSA:1.20.1250.20 1 204 2.3E-21 T 28-03-2018 CIG75_RS09250 f0c4df2393209f121d40f9e8423f6799 421 SUPERFAMILY SSF103473 12 408 1.83E-44 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS06910 f1f8eeab5e645a93fa96877dff9f0bf7 166 SUPERFAMILY SSF50346 93 156 1.55E-10 T 28-03-2018 IPR011033 PRC-barrel-like CIG75_RS06910 f1f8eeab5e645a93fa96877dff9f0bf7 166 SUPERFAMILY SSF50346 1 67 1.41E-6 T 28-03-2018 IPR011033 PRC-barrel-like CIG75_RS06910 f1f8eeab5e645a93fa96877dff9f0bf7 166 Gene3D G3DSA:2.30.30.240 91 160 7.6E-10 T 28-03-2018 CIG75_RS06910 f1f8eeab5e645a93fa96877dff9f0bf7 166 Gene3D G3DSA:2.30.30.240 1 72 1.9E-8 T 28-03-2018 CIG75_RS06910 f1f8eeab5e645a93fa96877dff9f0bf7 166 Pfam PF05239 PRC-barrel domain 3 67 1.1E-6 T 28-03-2018 IPR027275 PRC-barrel domain CIG75_RS06910 f1f8eeab5e645a93fa96877dff9f0bf7 166 Pfam PF05239 PRC-barrel domain 92 161 7.3E-13 T 28-03-2018 IPR027275 PRC-barrel domain CIG75_RS03480 d1d03beb28c85d8831cf50ca7ff179bc 517 Gene3D G3DSA:3.10.105.10 291 489 7.8E-59 T 28-03-2018 CIG75_RS03480 d1d03beb28c85d8831cf50ca7ff179bc 517 Gene3D G3DSA:3.40.190.10 196 290 1.3E-27 T 28-03-2018 CIG75_RS03480 d1d03beb28c85d8831cf50ca7ff179bc 517 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 88 439 6.2E-97 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CIG75_RS03480 d1d03beb28c85d8831cf50ca7ff179bc 517 SUPERFAMILY SSF53850 39 510 1.76E-141 T 28-03-2018 CIG75_RS03480 d1d03beb28c85d8831cf50ca7ff179bc 517 PIRSF PIRSF002741 3 516 3.6E-133 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CIG75_RS03480 d1d03beb28c85d8831cf50ca7ff179bc 517 Gene3D G3DSA:3.90.76.10 54 195 1.3E-41 T 28-03-2018 CIG75_RS20135 a331cdb880990a08e3c4a4243367eb51 180 Gene3D G3DSA:1.10.1740.10 14 85 7.6E-14 T 28-03-2018 CIG75_RS20135 a331cdb880990a08e3c4a4243367eb51 180 Pfam PF08281 Sigma-70, region 4 117 167 7.8E-10 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS20135 a331cdb880990a08e3c4a4243367eb51 180 SUPERFAMILY SSF88946 19 92 7.06E-14 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS20135 a331cdb880990a08e3c4a4243367eb51 180 SUPERFAMILY SSF88659 100 174 6.35E-12 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS20135 a331cdb880990a08e3c4a4243367eb51 180 Pfam PF04542 Sigma-70 region 2 23 88 2.9E-10 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS20135 a331cdb880990a08e3c4a4243367eb51 180 Gene3D G3DSA:1.10.10.10 86 175 1.7E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS20135 a331cdb880990a08e3c4a4243367eb51 180 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 20 170 3.3E-23 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS18820 a4b6f071f117e3b27f6fda0310f5bb07 414 Gene3D G3DSA:1.20.1250.20 1 203 3.4E-20 T 28-03-2018 CIG75_RS18820 a4b6f071f117e3b27f6fda0310f5bb07 414 Gene3D G3DSA:1.20.1250.20 205 396 9.5E-18 T 28-03-2018 CIG75_RS18820 a4b6f071f117e3b27f6fda0310f5bb07 414 SUPERFAMILY SSF103473 10 396 3.53E-40 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS18820 a4b6f071f117e3b27f6fda0310f5bb07 414 Pfam PF05977 Transmembrane secretion effector 6 352 1.8E-18 T 28-03-2018 IPR010290 Transmembrane secretion effector CIG75_RS05550 ebe4fb9c6c97347ac50ddac1a3f827b2 317 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 4 315 48.222 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CIG75_RS05550 ebe4fb9c6c97347ac50ddac1a3f827b2 317 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 3 316 2.4E-139 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CIG75_RS05550 ebe4fb9c6c97347ac50ddac1a3f827b2 317 Gene3D G3DSA:3.90.226.10 10 312 5.6E-62 T 28-03-2018 CIG75_RS05550 ebe4fb9c6c97347ac50ddac1a3f827b2 317 SUPERFAMILY SSF52096 5 315 3.27E-99 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CIG75_RS05550 ebe4fb9c6c97347ac50ddac1a3f827b2 317 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 6 147 1.5E-62 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CIG75_RS05550 ebe4fb9c6c97347ac50ddac1a3f827b2 317 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 112 130 2.4E-43 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CIG75_RS05550 ebe4fb9c6c97347ac50ddac1a3f827b2 317 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 133 149 2.4E-43 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CIG75_RS05550 ebe4fb9c6c97347ac50ddac1a3f827b2 317 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 196 205 2.4E-43 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CIG75_RS05550 ebe4fb9c6c97347ac50ddac1a3f827b2 317 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 152 165 2.4E-43 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CIG75_RS05550 ebe4fb9c6c97347ac50ddac1a3f827b2 317 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 168 181 2.4E-43 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CIG75_RS05550 ebe4fb9c6c97347ac50ddac1a3f827b2 317 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 87 98 2.4E-43 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CIG75_RS08210 f7ce8f9aa929bc4ef346328dd9c8dcd5 172 Pfam PF01202 Shikimate kinase 11 167 2.5E-44 T 28-03-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CIG75_RS08210 f7ce8f9aa929bc4ef346328dd9c8dcd5 172 Gene3D G3DSA:3.40.50.300 1 172 5.0E-28 T 28-03-2018 CIG75_RS08210 f7ce8f9aa929bc4ef346328dd9c8dcd5 172 PRINTS PR01100 Shikimate kinase family signature 57 65 7.0E-20 T 28-03-2018 CIG75_RS08210 f7ce8f9aa929bc4ef346328dd9c8dcd5 172 PRINTS PR01100 Shikimate kinase family signature 75 84 7.0E-20 T 28-03-2018 CIG75_RS08210 f7ce8f9aa929bc4ef346328dd9c8dcd5 172 PRINTS PR01100 Shikimate kinase family signature 96 113 7.0E-20 T 28-03-2018 CIG75_RS08210 f7ce8f9aa929bc4ef346328dd9c8dcd5 172 PRINTS PR01100 Shikimate kinase family signature 5 20 7.0E-20 T 28-03-2018 CIG75_RS08210 f7ce8f9aa929bc4ef346328dd9c8dcd5 172 PRINTS PR01100 Shikimate kinase family signature 29 42 7.0E-20 T 28-03-2018 CIG75_RS08210 f7ce8f9aa929bc4ef346328dd9c8dcd5 172 SUPERFAMILY SSF52540 3 167 1.05E-26 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS08210 f7ce8f9aa929bc4ef346328dd9c8dcd5 172 Hamap MF_00109 Shikimate kinase [aroK]. 2 168 26.489 T 28-03-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CIG75_RS14060 7cb98a93d9a51692aa03b63931d91625 391 Pfam PF02636 Putative S-adenosyl-L-methionine-dependent methyltransferase 63 325 2.0E-47 T 28-03-2018 IPR003788 Protein arginine methyltransferase NDUFAF7 Reactome: R-HSA-6799198 CIG75_RS14060 7cb98a93d9a51692aa03b63931d91625 391 SUPERFAMILY SSF53335 7 387 6.29E-80 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CIG75_RS14060 7cb98a93d9a51692aa03b63931d91625 391 Gene3D G3DSA:3.40.50.150 34 366 3.4E-6 T 28-03-2018 CIG75_RS17275 f861a605299e3884bb7c4511d190b755 99 Pfam PF11256 Protein of unknown function (DUF3055) 11 87 5.0E-16 T 28-03-2018 IPR021415 Protein of unknown function DUF3055 CIG75_RS12505 1d0a546477d603efbf2d91b8029145d7 318 Gene3D G3DSA:3.40.50.170 1 208 4.2E-73 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CIG75_RS12505 1d0a546477d603efbf2d91b8029145d7 318 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 4 308 37.492 T 28-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 CIG75_RS12505 1d0a546477d603efbf2d91b8029145d7 318 Pfam PF02911 Formyl transferase, C-terminal domain 207 305 3.5E-26 T 28-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CIG75_RS12505 1d0a546477d603efbf2d91b8029145d7 318 Gene3D G3DSA:3.10.25.10 209 317 3.2E-32 T 28-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CIG75_RS12505 1d0a546477d603efbf2d91b8029145d7 318 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 4 308 1.5E-107 T 28-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 CIG75_RS12505 1d0a546477d603efbf2d91b8029145d7 318 SUPERFAMILY SSF53328 4 208 1.7E-69 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CIG75_RS12505 1d0a546477d603efbf2d91b8029145d7 318 SUPERFAMILY SSF50486 207 313 1.73E-31 T 28-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 CIG75_RS12505 1d0a546477d603efbf2d91b8029145d7 318 Pfam PF00551 Formyl transferase 4 183 5.4E-44 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CIG75_RS09360 652454654f5e638b6cb0332bc0e1a34a 351 Pfam PF01070 FMN-dependent dehydrogenase 167 324 2.1E-19 T 28-03-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 CIG75_RS09360 652454654f5e638b6cb0332bc0e1a34a 351 TIGRFAM TIGR02151 IPP_isom_2: isopentenyl-diphosphate delta-isomerase, type 2 5 329 4.0E-115 T 28-03-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 CIG75_RS09360 652454654f5e638b6cb0332bc0e1a34a 351 Hamap MF_00354 Isopentenyl-diphosphate delta-isomerase [fni]. 3 330 37.911 T 28-03-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 CIG75_RS09360 652454654f5e638b6cb0332bc0e1a34a 351 Gene3D G3DSA:3.20.20.70 3 341 3.2E-69 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CIG75_RS09360 652454654f5e638b6cb0332bc0e1a34a 351 SUPERFAMILY SSF51395 23 344 3.61E-80 T 28-03-2018 CIG75_RS09360 652454654f5e638b6cb0332bc0e1a34a 351 PIRSF PIRSF003314 1 340 2.0E-117 T 28-03-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 CIG75_RS09360 652454654f5e638b6cb0332bc0e1a34a 351 SMART SM01240 21 341 6.2E-4 T 28-03-2018 CIG75_RS16935 ed249dc67c9542350eb6f56bf4d8bf79 222 Gene3D G3DSA:3.40.50.10230 10 222 3.2E-83 T 28-03-2018 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 CIG75_RS16935 ed249dc67c9542350eb6f56bf4d8bf79 222 SUPERFAMILY SSF63965 10 215 2.88E-70 T 28-03-2018 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 CIG75_RS16935 ed249dc67c9542350eb6f56bf4d8bf79 222 Pfam PF02570 Precorrin-8X methylmutase 16 212 7.3E-77 T 28-03-2018 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 CIG75_RS03140 a6f40db26cdc4c86e734c302e869ef01 343 SUPERFAMILY SSF69279 33 164 5.1E-7 T 28-03-2018 CIG75_RS16130 ccfcf40460b113ac7095a80633584be4 197 Pfam PF02632 BioY family 32 178 1.5E-32 T 28-03-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 CIG75_RS16130 ccfcf40460b113ac7095a80633584be4 197 PIRSF PIRSF016661 2 186 1.1E-35 T 28-03-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 CIG75_RS12235 49860cb66483f01862fec10536897935 276 SMART SM00518 3 274 8.8E-99 T 28-03-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 CIG75_RS12235 49860cb66483f01862fec10536897935 276 Pfam PF01261 Xylose isomerase-like TIM barrel 50 235 2.1E-31 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CIG75_RS12235 49860cb66483f01862fec10536897935 276 ProSitePatterns PS00730 AP endonucleases family 2 signature 2. 173 180 - T 28-03-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 CIG75_RS12235 49860cb66483f01862fec10536897935 276 SUPERFAMILY SSF51658 2 272 1.24E-83 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CIG75_RS12235 49860cb66483f01862fec10536897935 276 TIGRFAM TIGR00587 nfo: apurinic endonuclease (APN1) 4 271 3.1E-87 T 28-03-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 CIG75_RS12235 49860cb66483f01862fec10536897935 276 Gene3D G3DSA:3.20.20.150 1 273 5.0E-50 T 28-03-2018 CIG75_RS12235 49860cb66483f01862fec10536897935 276 ProSitePatterns PS00729 AP endonucleases family 2 signature 1. 68 76 - T 28-03-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 CIG75_RS12235 49860cb66483f01862fec10536897935 276 Hamap MF_00152 Probable endonuclease 4 [nfo]. 2 274 39.486 T 28-03-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 CIG75_RS20460 54e53c12e6c202c55df5c3e864c789cc 293 PIRSF PIRSF005917 6 293 5.4E-104 T 28-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CIG75_RS20460 54e53c12e6c202c55df5c3e864c789cc 293 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 16 235 37.026 T 28-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CIG75_RS20460 54e53c12e6c202c55df5c3e864c789cc 293 Gene3D G3DSA:3.40.1010.10 14 125 1.7E-42 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CIG75_RS20460 54e53c12e6c202c55df5c3e864c789cc 293 Gene3D G3DSA:3.30.950.10 126 238 7.2E-39 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CIG75_RS20460 54e53c12e6c202c55df5c3e864c789cc 293 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 17 291 1.4E-77 T 28-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CIG75_RS20460 54e53c12e6c202c55df5c3e864c789cc 293 SUPERFAMILY SSF53790 15 233 9.55E-82 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CIG75_RS20460 54e53c12e6c202c55df5c3e864c789cc 293 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 95 106 - T 28-03-2018 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CIG75_RS20460 54e53c12e6c202c55df5c3e864c789cc 293 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 16 215 1.2E-28 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CIG75_RS04290 cd6c4d9427b3bebfd54d043d416df217 541 PRINTS PR01036 Tetracycline resistance protein TetB signature 357 377 2.0E-6 T 28-03-2018 CIG75_RS04290 cd6c4d9427b3bebfd54d043d416df217 541 PRINTS PR01036 Tetracycline resistance protein TetB signature 15 39 2.0E-6 T 28-03-2018 CIG75_RS04290 cd6c4d9427b3bebfd54d043d416df217 541 PRINTS PR01036 Tetracycline resistance protein TetB signature 399 418 2.0E-6 T 28-03-2018 CIG75_RS04290 cd6c4d9427b3bebfd54d043d416df217 541 PRINTS PR01036 Tetracycline resistance protein TetB signature 135 159 2.0E-6 T 28-03-2018 CIG75_RS04290 cd6c4d9427b3bebfd54d043d416df217 541 PRINTS PR01036 Tetracycline resistance protein TetB signature 74 96 2.0E-6 T 28-03-2018 CIG75_RS04290 cd6c4d9427b3bebfd54d043d416df217 541 Pfam PF07690 Major Facilitator Superfamily 18 408 6.0E-50 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CIG75_RS04290 cd6c4d9427b3bebfd54d043d416df217 541 Gene3D G3DSA:1.20.1250.20 1 195 1.1E-38 T 28-03-2018 CIG75_RS04290 cd6c4d9427b3bebfd54d043d416df217 541 SUPERFAMILY SSF103473 488 521 1.44E-34 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS04290 cd6c4d9427b3bebfd54d043d416df217 541 SUPERFAMILY SSF103473 201 418 1.44E-34 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS04290 cd6c4d9427b3bebfd54d043d416df217 541 ProSitePatterns PS00216 Sugar transport proteins signature 1. 65 81 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CIG75_RS04290 cd6c4d9427b3bebfd54d043d416df217 541 SUPERFAMILY SSF103473 5 186 6.93E-45 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS04290 cd6c4d9427b3bebfd54d043d416df217 541 Gene3D G3DSA:1.20.1250.20 250 527 5.4E-37 T 28-03-2018 CIG75_RS04290 cd6c4d9427b3bebfd54d043d416df217 541 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 10 510 8.8E-82 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CIG75_RS20155 c346e72c44fe529b5989369842ee7db2 645 Pfam PF02824 TGS domain 1 61 4.1E-12 T 28-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 CIG75_RS20155 c346e72c44fe529b5989369842ee7db2 645 SUPERFAMILY SSF81271 1 62 4.58E-15 T 28-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CIG75_RS20155 c346e72c44fe529b5989369842ee7db2 645 SUPERFAMILY SSF52954 528 632 3.93E-29 T 28-03-2018 IPR004154 Anticodon-binding CIG75_RS20155 c346e72c44fe529b5989369842ee7db2 645 SUPERFAMILY SSF55186 63 240 1.14E-63 T 28-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 CIG75_RS20155 c346e72c44fe529b5989369842ee7db2 645 Gene3D G3DSA:3.30.980.10 65 141 7.3E-24 T 28-03-2018 CIG75_RS20155 c346e72c44fe529b5989369842ee7db2 645 Pfam PF03129 Anticodon binding domain 539 626 5.5E-21 T 28-03-2018 IPR004154 Anticodon-binding CIG75_RS20155 c346e72c44fe529b5989369842ee7db2 645 PRINTS PR01047 Threonyl-tRNA synthetase signature 462 490 2.7E-51 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CIG75_RS20155 c346e72c44fe529b5989369842ee7db2 645 PRINTS PR01047 Threonyl-tRNA synthetase signature 505 518 2.7E-51 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CIG75_RS20155 c346e72c44fe529b5989369842ee7db2 645 PRINTS PR01047 Threonyl-tRNA synthetase signature 532 544 2.7E-51 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CIG75_RS20155 c346e72c44fe529b5989369842ee7db2 645 PRINTS PR01047 Threonyl-tRNA synthetase signature 361 384 2.7E-51 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CIG75_RS20155 c346e72c44fe529b5989369842ee7db2 645 PRINTS PR01047 Threonyl-tRNA synthetase signature 328 356 2.7E-51 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CIG75_RS20155 c346e72c44fe529b5989369842ee7db2 645 Gene3D G3DSA:3.30.54.20 142 186 4.7E-18 T 28-03-2018 CIG75_RS20155 c346e72c44fe529b5989369842ee7db2 645 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 170 218 2.2E-13 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CIG75_RS20155 c346e72c44fe529b5989369842ee7db2 645 SUPERFAMILY SSF55681 242 524 4.52E-90 T 28-03-2018 CIG75_RS20155 c346e72c44fe529b5989369842ee7db2 645 Gene3D G3DSA:3.30.930.10 220 529 1.3E-114 T 28-03-2018 CIG75_RS20155 c346e72c44fe529b5989369842ee7db2 645 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 72 629 2.0E-211 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CIG75_RS20155 c346e72c44fe529b5989369842ee7db2 645 Gene3D G3DSA:3.40.50.800 530 644 1.8E-25 T 28-03-2018 IPR004154 Anticodon-binding CIG75_RS20155 c346e72c44fe529b5989369842ee7db2 645 SMART SM00863 169 218 6.8E-21 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CIG75_RS20155 c346e72c44fe529b5989369842ee7db2 645 Gene3D G3DSA:3.10.20.30 1 63 1.5E-21 T 28-03-2018 IPR012675 Beta-grasp domain CIG75_RS20155 c346e72c44fe529b5989369842ee7db2 645 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 66 632 33.09 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CIG75_RS20155 c346e72c44fe529b5989369842ee7db2 645 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 321 526 1.0E-40 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CIG75_RS11575 4ba018f27a837e95428ab0dd407b1278 229 Hamap MF_01114 Regulatory protein RecX [recX]. 55 224 16.065 T 28-03-2018 IPR003783 Regulatory protein RecX GO:0006282 CIG75_RS11575 4ba018f27a837e95428ab0dd407b1278 229 Gene3D G3DSA:1.10.10.10 123 166 2.9E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS11575 4ba018f27a837e95428ab0dd407b1278 229 Gene3D G3DSA:1.10.10.10 173 220 2.8E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS11575 4ba018f27a837e95428ab0dd407b1278 229 Gene3D G3DSA:1.10.10.10 56 121 7.6E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS11575 4ba018f27a837e95428ab0dd407b1278 229 Pfam PF02631 RecX family 99 219 4.8E-28 T 28-03-2018 IPR003783 Regulatory protein RecX GO:0006282 CIG75_RS19765 9f0e75d395612753b0022b8b2a7db3e3 1220 Pfam PF04998 RNA polymerase Rpb1, domain 5 771 1130 1.4E-68 T 28-03-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CIG75_RS19765 9f0e75d395612753b0022b8b2a7db3e3 1220 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 4 1192 18.547 T 28-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CIG75_RS19765 9f0e75d395612753b0022b8b2a7db3e3 1220 Gene3D G3DSA:2.40.40.20 335 477 3.6E-39 T 28-03-2018 CIG75_RS19765 9f0e75d395612753b0022b8b2a7db3e3 1220 Gene3D G3DSA:2.40.50.100 911 1029 4.0E-42 T 28-03-2018 CIG75_RS19765 9f0e75d395612753b0022b8b2a7db3e3 1220 Pfam PF05000 RNA polymerase Rpb1, domain 4 694 761 7.5E-14 T 28-03-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CIG75_RS19765 9f0e75d395612753b0022b8b2a7db3e3 1220 Pfam PF04997 RNA polymerase Rpb1, domain 1 6 331 6.0E-88 T 28-03-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CIG75_RS19765 9f0e75d395612753b0022b8b2a7db3e3 1220 SUPERFAMILY SSF64484 5 1182 0.0 T 28-03-2018 CIG75_RS19765 9f0e75d395612753b0022b8b2a7db3e3 1220 Pfam PF04983 RNA polymerase Rpb1, domain 3 478 664 1.9E-32 T 28-03-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CIG75_RS19765 9f0e75d395612753b0022b8b2a7db3e3 1220 SMART SM00663 224 503 6.3E-185 T 28-03-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CIG75_RS19765 9f0e75d395612753b0022b8b2a7db3e3 1220 Pfam PF00623 RNA polymerase Rpb1, domain 2 378 474 2.8E-29 T 28-03-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CIG75_RS19765 9f0e75d395612753b0022b8b2a7db3e3 1220 Pfam PF00623 RNA polymerase Rpb1, domain 2 333 386 7.5E-9 T 28-03-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CIG75_RS19765 9f0e75d395612753b0022b8b2a7db3e3 1220 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 10 1182 0.0 T 28-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CIG75_RS03745 9161d3a7ddec4523733eebef5729b589 491 Pfam PF02696 Uncharacterized ACR, YdiU/UPF0061 family 15 460 6.6E-122 T 28-03-2018 IPR003846 Uncharacterised protein family UPF0061 CIG75_RS03745 9161d3a7ddec4523733eebef5729b589 491 Hamap MF_00692 UPF0061 protein YdiU [ydiU]. 10 477 45.934 T 28-03-2018 IPR003846 Uncharacterised protein family UPF0061 CIG75_RS03285 287519aae52bf0c2a91d6870bfaf3782 377 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 121 211 4.1E-22 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CIG75_RS03285 287519aae52bf0c2a91d6870bfaf3782 377 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 373 4.0E-43 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CIG75_RS03285 287519aae52bf0c2a91d6870bfaf3782 377 Gene3D G3DSA:1.10.540.10 1 119 2.6E-30 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CIG75_RS03285 287519aae52bf0c2a91d6870bfaf3782 377 Gene3D G3DSA:1.20.140.10 215 377 1.1E-48 T 28-03-2018 CIG75_RS03285 287519aae52bf0c2a91d6870bfaf3782 377 Gene3D G3DSA:2.40.110.10 120 214 1.2E-30 T 28-03-2018 CIG75_RS03285 287519aae52bf0c2a91d6870bfaf3782 377 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 332 351 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CIG75_RS03285 287519aae52bf0c2a91d6870bfaf3782 377 SUPERFAMILY SSF47203 229 375 2.9E-46 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CIG75_RS03285 287519aae52bf0c2a91d6870bfaf3782 377 PIRSF PIRSF016578 1 357 2.9E-17 T 28-03-2018 CIG75_RS03285 287519aae52bf0c2a91d6870bfaf3782 377 SUPERFAMILY SSF56645 3 227 2.23E-70 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CIG75_RS03285 287519aae52bf0c2a91d6870bfaf3782 377 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 117 3.0E-28 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CIG75_RS18450 906402a764cd4ab127f43f63d65c9b88 299 Pfam PF00892 EamA-like transporter family 4 138 6.3E-14 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CIG75_RS18450 906402a764cd4ab127f43f63d65c9b88 299 Pfam PF00892 EamA-like transporter family 151 284 4.2E-12 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CIG75_RS18450 906402a764cd4ab127f43f63d65c9b88 299 SUPERFAMILY SSF103481 195 286 1.18E-8 T 28-03-2018 CIG75_RS18450 906402a764cd4ab127f43f63d65c9b88 299 SUPERFAMILY SSF103481 42 138 2.35E-9 T 28-03-2018 CIG75_RS07775 f654fc245f9ef111708eec59ddcac18b 426 Gene3D G3DSA:1.20.1250.20 1 201 1.2E-18 T 28-03-2018 CIG75_RS07775 f654fc245f9ef111708eec59ddcac18b 426 SUPERFAMILY SSF103473 11 410 9.55E-45 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS07775 f654fc245f9ef111708eec59ddcac18b 426 Gene3D G3DSA:1.20.1250.20 202 426 2.4E-15 T 28-03-2018 CIG75_RS07775 f654fc245f9ef111708eec59ddcac18b 426 Pfam PF07690 Major Facilitator Superfamily 19 375 2.0E-27 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CIG75_RS20245 cc1720d9738298b4d0be4ea5607fba32 549 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 374 521 4.2E-28 T 28-03-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain CIG75_RS20245 cc1720d9738298b4d0be4ea5607fba32 549 Pfam PF01943 Polysaccharide biosynthesis protein 16 319 4.0E-41 T 28-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 CIG75_RS20245 cc1720d9738298b4d0be4ea5607fba32 549 PIRSF PIRSF038958 11 538 6.8E-131 T 28-03-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type CIG75_RS04995 e5a019af83f009b93cc6019ac90c1a07 232 SUPERFAMILY SSF46785 7 89 1.24E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS04995 e5a019af83f009b93cc6019ac90c1a07 232 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 2.5E-23 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CIG75_RS04995 e5a019af83f009b93cc6019ac90c1a07 232 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 5.9E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CIG75_RS04995 e5a019af83f009b93cc6019ac90c1a07 232 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 5.9E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CIG75_RS04995 e5a019af83f009b93cc6019ac90c1a07 232 SMART SM00345 15 74 3.3E-25 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CIG75_RS04995 e5a019af83f009b93cc6019ac90c1a07 232 Pfam PF07729 FCD domain 100 221 1.0E-27 T 28-03-2018 IPR011711 GntR, C-terminal CIG75_RS04995 e5a019af83f009b93cc6019ac90c1a07 232 Gene3D G3DSA:1.10.10.10 1 76 1.5E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS04995 e5a019af83f009b93cc6019ac90c1a07 232 SMART SM00895 100 222 7.6E-23 T 28-03-2018 IPR011711 GntR, C-terminal CIG75_RS04995 e5a019af83f009b93cc6019ac90c1a07 232 Gene3D G3DSA:1.20.120.530 82 232 1.2E-31 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CIG75_RS04995 e5a019af83f009b93cc6019ac90c1a07 232 SUPERFAMILY SSF48008 97 228 6.28E-31 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CIG75_RS03750 b9f6fa61fc0f05ef036d1b41fdc38aae 186 SUPERFAMILY SSF55729 7 180 1.1E-45 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CIG75_RS03750 b9f6fa61fc0f05ef036d1b41fdc38aae 186 Gene3D G3DSA:3.40.630.30 5 186 1.1E-24 T 28-03-2018 CIG75_RS03750 b9f6fa61fc0f05ef036d1b41fdc38aae 186 Pfam PF13302 Acetyltransferase (GNAT) domain 14 154 4.8E-30 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CIG75_RS02535 91affca6f254dbc4a3954ac68a0b3c66 350 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 165 334 5.7E-15 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CIG75_RS02535 91affca6f254dbc4a3954ac68a0b3c66 350 SUPERFAMILY SSF52266 156 346 6.91E-28 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CIG75_RS02535 91affca6f254dbc4a3954ac68a0b3c66 350 Gene3D G3DSA:3.40.50.1110 143 350 4.7E-25 T 28-03-2018 CIG75_RS16330 ba949e16c44afab65f2e3f102a047d05 212 Pfam PF10648 Immunoglobulin-like domain of bacterial spore germination 136 200 5.9E-8 T 28-03-2018 IPR018911 Bacterial spore germination, immunoglobulin-like domain CIG75_RS06700 8f9738c1dafa7be31f8a49bb897ac064 508 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 34 493 2.3E-144 T 28-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 CIG75_RS06700 8f9738c1dafa7be31f8a49bb897ac064 508 PIRSF PIRSF005690 18 508 1.4E-142 T 28-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 CIG75_RS18385 b30aead26f7eedf4036977b7cbe5a4ae 286 Gene3D G3DSA:3.30.240.20 82 151 6.3E-24 T 28-03-2018 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain CIG75_RS18385 b30aead26f7eedf4036977b7cbe5a4ae 286 Pfam PF07870 Protein of unknown function (DUF1657) 236 283 7.8E-12 T 28-03-2018 IPR012452 Protein of unknown function DUF1657 CIG75_RS18385 b30aead26f7eedf4036977b7cbe5a4ae 286 Pfam PF04239 Protein of unknown function (DUF421) 89 203 2.0E-32 T 28-03-2018 IPR007353 Protein of unknown function DUF421 CIG75_RS18385 b30aead26f7eedf4036977b7cbe5a4ae 286 Gene3D G3DSA:3.30.240.20 170 225 8.9E-14 T 28-03-2018 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain CIG75_RS02650 5c640fff5affd4d06f9a4bfd06ac390f 499 Gene3D G3DSA:1.10.10.10 5 41 0.0017 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS02650 5c640fff5affd4d06f9a4bfd06ac390f 499 Gene3D G3DSA:3.30.420.10 121 318 1.9E-16 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CIG75_RS02650 5c640fff5affd4d06f9a4bfd06ac390f 499 Pfam PF00665 Integrase core domain 127 254 1.4E-13 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CIG75_RS02650 5c640fff5affd4d06f9a4bfd06ac390f 499 SUPERFAMILY SSF53098 124 277 1.74E-7 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CIG75_RS01960 6e294c53400d0295e16d7aa5fcceeec1 168 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 7 159 42.078 T 28-03-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CIG75_RS01960 6e294c53400d0295e16d7aa5fcceeec1 168 SUPERFAMILY SSF56770 17 161 3.4E-65 T 28-03-2018 CIG75_RS01960 6e294c53400d0295e16d7aa5fcceeec1 168 Gene3D G3DSA:3.40.50.700 20 168 3.9E-47 T 28-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CIG75_RS01960 6e294c53400d0295e16d7aa5fcceeec1 168 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 45 154 1.2E-24 T 28-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CIG75_RS01960 6e294c53400d0295e16d7aa5fcceeec1 168 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 19 159 1.2E-70 T 28-03-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CIG75_RS19870 c996c8f73476344a183092e8bd07cde3 358 Pfam PF10635 DisA bacterial checkpoint controller linker region 143 281 5.4E-56 T 28-03-2018 IPR018906 DNA integrity scanning, DisA, linker region CIG75_RS19870 c996c8f73476344a183092e8bd07cde3 358 Gene3D G3DSA:3.40.1700.10 7 143 4.2E-26 T 28-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal CIG75_RS19870 c996c8f73476344a183092e8bd07cde3 358 Hamap MF_01438 DNA integrity scanning protein DisA [disA]. 5 355 45.359 T 28-03-2018 IPR023763 DNA integrity scanning protein, DisA CIG75_RS19870 c996c8f73476344a183092e8bd07cde3 358 Pfam PF00633 Helix-hairpin-helix motif 317 343 3.9E-6 T 28-03-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 CIG75_RS19870 c996c8f73476344a183092e8bd07cde3 358 SUPERFAMILY SSF47781 292 346 8.53E-11 T 28-03-2018 IPR010994 RuvA domain 2-like CIG75_RS19870 c996c8f73476344a183092e8bd07cde3 358 SUPERFAMILY SSF143597 19 143 7.19E-31 T 28-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal CIG75_RS19870 c996c8f73476344a183092e8bd07cde3 358 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 26 137 4.8E-26 T 28-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal CIG75_RS19870 c996c8f73476344a183092e8bd07cde3 358 Gene3D G3DSA:1.10.150.20 291 355 1.9E-8 T 28-03-2018 CIG75_RS07450 ccb409677e59dbd412af009148c2d4e1 160 Pfam PF00293 NUDIX domain 10 123 4.0E-18 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CIG75_RS07450 ccb409677e59dbd412af009148c2d4e1 160 SUPERFAMILY SSF55811 7 134 5.01E-27 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CIG75_RS07450 ccb409677e59dbd412af009148c2d4e1 160 ProSitePatterns PS00893 Nudix box signature. 42 63 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CIG75_RS07450 ccb409677e59dbd412af009148c2d4e1 160 PRINTS PR00502 NUDIX hydrolase family signature 37 51 1.3E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CIG75_RS07450 ccb409677e59dbd412af009148c2d4e1 160 PRINTS PR00502 NUDIX hydrolase family signature 51 66 1.3E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CIG75_RS07450 ccb409677e59dbd412af009148c2d4e1 160 Gene3D G3DSA:3.90.79.10 2 140 5.7E-25 T 28-03-2018 CIG75_RS11360 03ff4e5f8ec41813e2dba305838ccd1f 267 SUPERFAMILY SSF55347 130 238 1.02E-36 T 28-03-2018 CIG75_RS11360 03ff4e5f8ec41813e2dba305838ccd1f 267 SUPERFAMILY SSF51735 4 155 3.0E-38 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS11360 03ff4e5f8ec41813e2dba305838ccd1f 267 PIRSF PIRSF000161 3 267 6.0E-75 T 28-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CIG75_RS11360 03ff4e5f8ec41813e2dba305838ccd1f 267 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 5 266 1.3E-81 T 28-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CIG75_RS11360 03ff4e5f8ec41813e2dba305838ccd1f 267 Gene3D G3DSA:3.40.50.720 1 124 1.8E-32 T 28-03-2018 CIG75_RS11360 03ff4e5f8ec41813e2dba305838ccd1f 267 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 5 267 29.452 T 28-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CIG75_RS11360 03ff4e5f8ec41813e2dba305838ccd1f 267 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 132 266 5.9E-33 T 28-03-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CIG75_RS11360 03ff4e5f8ec41813e2dba305838ccd1f 267 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 151 168 - T 28-03-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CIG75_RS11360 03ff4e5f8ec41813e2dba305838ccd1f 267 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 5 129 2.5E-32 T 28-03-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CIG75_RS11360 03ff4e5f8ec41813e2dba305838ccd1f 267 Gene3D G3DSA:3.30.360.10 131 235 5.3E-36 T 28-03-2018 CIG75_RS12655 7c721889d2a7ea29ac93478416a46d4a 283 Gene3D G3DSA:3.40.50.450 1 157 7.9E-23 T 28-03-2018 CIG75_RS12655 7c721889d2a7ea29ac93478416a46d4a 283 SUPERFAMILY SSF52309 34 110 7.02E-5 T 28-03-2018 CIG75_RS03945 e7807a6d55cdd39bed02230d0cff32a2 146 SUPERFAMILY SSF54909 55 137 7.51E-9 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CIG75_RS03945 e7807a6d55cdd39bed02230d0cff32a2 146 Gene3D G3DSA:3.30.70.100 7 146 6.0E-35 T 28-03-2018 CIG75_RS00245 00809485a0fda2ea6f121d5436a86686 229 Pfam PF13083 KH domain 68 131 2.1E-17 T 28-03-2018 CIG75_RS00245 00809485a0fda2ea6f121d5436a86686 229 Gene3D G3DSA:3.30.1370.50 140 226 1.5E-18 T 28-03-2018 IPR001374 R3H domain GO:0003676 CIG75_RS00245 00809485a0fda2ea6f121d5436a86686 229 Gene3D G3DSA:3.30.30.80 3 54 1.5E-18 T 28-03-2018 CIG75_RS00245 00809485a0fda2ea6f121d5436a86686 229 Gene3D G3DSA:3.30.300.20 59 138 8.9E-20 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CIG75_RS00245 00809485a0fda2ea6f121d5436a86686 229 SMART SM00393 129 208 6.0E-18 T 28-03-2018 IPR001374 R3H domain GO:0003676 CIG75_RS00245 00809485a0fda2ea6f121d5436a86686 229 SMART SM01245 5 57 1.5E-19 T 28-03-2018 IPR032782 Jag, N-terminal CIG75_RS00245 00809485a0fda2ea6f121d5436a86686 229 SUPERFAMILY SSF82708 151 208 1.88E-8 T 28-03-2018 IPR001374 R3H domain GO:0003676 CIG75_RS00245 00809485a0fda2ea6f121d5436a86686 229 Pfam PF01424 R3H domain 147 206 4.5E-16 T 28-03-2018 IPR001374 R3H domain GO:0003676 CIG75_RS00245 00809485a0fda2ea6f121d5436a86686 229 Pfam PF14804 Jag N-terminus 7 55 3.1E-19 T 28-03-2018 IPR032782 Jag, N-terminal CIG75_RS07995 dfd62f955cae3db24676a3bade602f3a 176 Gene3D G3DSA:2.30.260.10 101 176 1.2E-21 T 28-03-2018 CIG75_RS07995 dfd62f955cae3db24676a3bade602f3a 176 Pfam PF07833 Copper amine oxidase N-terminal domain 8 44 1.3E-6 T 28-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CIG75_RS07995 dfd62f955cae3db24676a3bade602f3a 176 Gene3D G3DSA:3.30.457.10 1 25 7.7E-5 T 28-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CIG75_RS07995 dfd62f955cae3db24676a3bade602f3a 176 Pfam PF00877 NlpC/P60 family 68 173 2.0E-31 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CIG75_RS07995 dfd62f955cae3db24676a3bade602f3a 176 SUPERFAMILY SSF55383 1 31 3.92E-6 T 28-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CIG75_RS07995 dfd62f955cae3db24676a3bade602f3a 176 Gene3D G3DSA:3.90.1720.10 26 100 1.4E-21 T 28-03-2018 CIG75_RS07995 dfd62f955cae3db24676a3bade602f3a 176 SUPERFAMILY SSF54001 55 175 2.94E-45 T 28-03-2018 CIG75_RS08245 d0f62d067a782de360e498e3e266ce5f 300 Pfam PF11079 Bacterial protein YqhG of unknown function 13 253 1.9E-45 T 28-03-2018 IPR024562 Uncharacterised protein family YqhG CIG75_RS08245 d0f62d067a782de360e498e3e266ce5f 300 ProDom PD123329 YQHG BH2818 16 284 2.0E-22 T 28-03-2018 IPR024562 Uncharacterised protein family YqhG CIG75_RS09105 03d7dc4a2011d092650890524648a16a 257 SUPERFAMILY SSF51735 4 253 3.1E-68 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS09105 03d7dc4a2011d092650890524648a16a 257 Pfam PF00106 short chain dehydrogenase 7 197 1.8E-52 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS09105 03d7dc4a2011d092650890524648a16a 257 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CIG75_RS09105 03d7dc4a2011d092650890524648a16a 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 1.8E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS09105 03d7dc4a2011d092650890524648a16a 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.8E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS09105 03d7dc4a2011d092650890524648a16a 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 1.8E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS09105 03d7dc4a2011d092650890524648a16a 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 1.8E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS09105 03d7dc4a2011d092650890524648a16a 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 1.8E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS09105 03d7dc4a2011d092650890524648a16a 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 204 224 1.8E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS09105 03d7dc4a2011d092650890524648a16a 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 5.2E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS09105 03d7dc4a2011d092650890524648a16a 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 5.2E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS09105 03d7dc4a2011d092650890524648a16a 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 5.2E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS09105 03d7dc4a2011d092650890524648a16a 257 Gene3D G3DSA:3.40.50.720 2 257 1.3E-60 T 28-03-2018 CIG75_RS09105 03d7dc4a2011d092650890524648a16a 257 PIRSF PIRSF000126 2 256 1.8E-51 T 28-03-2018 CIG75_RS13515 94a26dd51cece20d1fbac1124dffc958 639 SUPERFAMILY SSF54184 577 634 5.36E-9 T 28-03-2018 CIG75_RS13515 94a26dd51cece20d1fbac1124dffc958 639 SMART SM00740 573 635 2.9E-14 T 28-03-2018 IPR005543 PASTA domain CIG75_RS13515 94a26dd51cece20d1fbac1124dffc958 639 TIGRFAM TIGR02214 spoVD_pbp: stage V sporulation protein D 5 635 8.2E-237 T 28-03-2018 IPR011927 Stage V sporulation protein D CIG75_RS13515 94a26dd51cece20d1fbac1124dffc958 639 SUPERFAMILY SSF56601 165 586 1.4E-103 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CIG75_RS13515 94a26dd51cece20d1fbac1124dffc958 639 Gene3D G3DSA:3.40.710.10 211 555 1.7E-97 T 28-03-2018 CIG75_RS13515 94a26dd51cece20d1fbac1124dffc958 639 Pfam PF03793 PASTA domain 577 634 5.4E-11 T 28-03-2018 IPR005543 PASTA domain CIG75_RS13515 94a26dd51cece20d1fbac1124dffc958 639 Pfam PF03717 Penicillin-binding Protein dimerisation domain 49 195 2.0E-20 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CIG75_RS13515 94a26dd51cece20d1fbac1124dffc958 639 Pfam PF00905 Penicillin binding protein transpeptidase domain 241 549 1.2E-81 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CIG75_RS13515 94a26dd51cece20d1fbac1124dffc958 639 Gene3D G3DSA:3.90.1310.10 18 210 6.8E-42 T 28-03-2018 CIG75_RS13515 94a26dd51cece20d1fbac1124dffc958 639 SUPERFAMILY SSF56519 45 213 5.62E-43 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CIG75_RS11935 bc4e960938e054a27204d022fa488513 207 Pfam PF04509 CheC-like family 110 145 8.1E-12 T 28-03-2018 IPR007597 CheC-like protein GO:0016787 CIG75_RS11935 bc4e960938e054a27204d022fa488513 207 Pfam PF04509 CheC-like family 10 46 1.9E-10 T 28-03-2018 IPR007597 CheC-like protein GO:0016787 CIG75_RS11935 bc4e960938e054a27204d022fa488513 207 SUPERFAMILY SSF103039 6 204 9.02E-56 T 28-03-2018 IPR028976 CheC-like domain CIG75_RS11935 bc4e960938e054a27204d022fa488513 207 Gene3D G3DSA:3.40.1550.10 5 204 2.6E-57 T 28-03-2018 IPR028976 CheC-like domain CIG75_RS01015 bb840088a92c94f8fb1c6f9b6a854901 511 SUPERFAMILY SSF53807 267 449 1.81E-15 T 28-03-2018 CIG75_RS01015 bb840088a92c94f8fb1c6f9b6a854901 511 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 216 258 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CIG75_RS01015 bb840088a92c94f8fb1c6f9b6a854901 511 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 246 262 4.1E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CIG75_RS01015 bb840088a92c94f8fb1c6f9b6a854901 511 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 231 246 4.1E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CIG75_RS01015 bb840088a92c94f8fb1c6f9b6a854901 511 Pfam PF12833 Helix-turn-helix domain 185 262 4.6E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CIG75_RS01015 bb840088a92c94f8fb1c6f9b6a854901 511 Gene3D G3DSA:3.40.50.1980 339 470 3.2E-6 T 28-03-2018 CIG75_RS01015 bb840088a92c94f8fb1c6f9b6a854901 511 SUPERFAMILY SSF46689 216 262 1.52E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CIG75_RS01015 bb840088a92c94f8fb1c6f9b6a854901 511 Gene3D G3DSA:1.10.10.60 230 249 6.9E-8 T 28-03-2018 CIG75_RS01015 bb840088a92c94f8fb1c6f9b6a854901 511 Gene3D G3DSA:3.90.1240.10 131 229 9.4E-16 T 28-03-2018 CIG75_RS01015 bb840088a92c94f8fb1c6f9b6a854901 511 Gene3D G3DSA:3.90.1240.10 250 270 0.016 T 28-03-2018 CIG75_RS01015 bb840088a92c94f8fb1c6f9b6a854901 511 SUPERFAMILY SSF46689 165 212 2.22E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CIG75_RS01015 bb840088a92c94f8fb1c6f9b6a854901 511 SMART SM00342 179 262 2.6E-28 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CIG75_RS17890 c1c867f6ee8c3d25df0dd9605b9b6d64 362 SUPERFAMILY SSF55874 235 357 3.14E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS17890 c1c867f6ee8c3d25df0dd9605b9b6d64 362 PIRSF PIRSF037434 3 106 18.0 T 28-03-2018 IPR017205 Signal transduction histidine kinase, ChrS CIG75_RS17890 c1c867f6ee8c3d25df0dd9605b9b6d64 362 PIRSF PIRSF037434 123 361 1.1E-49 T 28-03-2018 IPR017205 Signal transduction histidine kinase, ChrS CIG75_RS17890 c1c867f6ee8c3d25df0dd9605b9b6d64 362 SMART SM00304 88 141 2.5E-6 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CIG75_RS17890 c1c867f6ee8c3d25df0dd9605b9b6d64 362 SMART SM00387 269 362 1.1E-10 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS17890 c1c867f6ee8c3d25df0dd9605b9b6d64 362 Gene3D G3DSA:3.30.565.10 229 362 2.2E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS17890 c1c867f6ee8c3d25df0dd9605b9b6d64 362 SUPERFAMILY SSF158472 89 138 1.01E-5 T 28-03-2018 CIG75_RS17890 c1c867f6ee8c3d25df0dd9605b9b6d64 362 Pfam PF07730 Histidine kinase 165 232 1.8E-17 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CIG75_RS17890 c1c867f6ee8c3d25df0dd9605b9b6d64 362 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 271 359 1.5E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS20410 cf710f9a16ebe124f3a628fc51f59583 144 Pfam PF07291 Methylamine utilisation protein MauE 7 128 4.4E-10 T 28-03-2018 IPR009908 Methylamine utilisation protein, MauE GO:0016021|GO:0030416 CIG75_RS07745 f2daf09fc02fff26abea536dc5e3ddbc 582 Gene3D G3DSA:4.10.80.40 530 579 9.0E-7 T 28-03-2018 CIG75_RS07745 f2daf09fc02fff26abea536dc5e3ddbc 582 TIGRFAM TIGR01811 sdhA_Bsu: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 6 577 5.7E-265 T 28-03-2018 IPR011280 Succinate dehydrogenase/fumarate reductase flavoprotein subunit, low-GC Gram-positive bacteria KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279 CIG75_RS07745 f2daf09fc02fff26abea536dc5e3ddbc 582 SUPERFAMILY SSF46977 443 577 3.4E-44 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CIG75_RS07745 f2daf09fc02fff26abea536dc5e3ddbc 582 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 356 378 3.6E-8 T 28-03-2018 CIG75_RS07745 f2daf09fc02fff26abea536dc5e3ddbc 582 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 3.6E-8 T 28-03-2018 CIG75_RS07745 f2daf09fc02fff26abea536dc5e3ddbc 582 SUPERFAMILY SSF56425 231 353 4.19E-33 T 28-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CIG75_RS07745 f2daf09fc02fff26abea536dc5e3ddbc 582 Gene3D G3DSA:1.20.58.100 448 529 2.5E-20 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CIG75_RS07745 f2daf09fc02fff26abea536dc5e3ddbc 582 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 39 48 - T 28-03-2018 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CIG75_RS07745 f2daf09fc02fff26abea536dc5e3ddbc 582 Pfam PF02910 Fumarate reductase flavoprotein C-term 452 577 1.0E-41 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CIG75_RS07745 f2daf09fc02fff26abea536dc5e3ddbc 582 SUPERFAMILY SSF51905 357 426 3.11E-61 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS07745 f2daf09fc02fff26abea536dc5e3ddbc 582 SUPERFAMILY SSF51905 5 247 3.11E-61 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS07745 f2daf09fc02fff26abea536dc5e3ddbc 582 Gene3D G3DSA:3.50.50.60 3 447 1.3E-55 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS07745 f2daf09fc02fff26abea536dc5e3ddbc 582 PIRSF PIRSF000171 341 572 2.3E-16 T 28-03-2018 CIG75_RS07745 f2daf09fc02fff26abea536dc5e3ddbc 582 PIRSF PIRSF000171 1 240 1.5E-16 T 28-03-2018 CIG75_RS07745 f2daf09fc02fff26abea536dc5e3ddbc 582 Pfam PF00890 FAD binding domain 6 392 5.0E-88 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CIG75_RS15975 7676d10d181db8ab826ebcca52fe93bd 453 SMART SM00729 47 270 1.7E-39 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CIG75_RS15975 7676d10d181db8ab826ebcca52fe93bd 453 Pfam PF04055 Radical SAM superfamily 52 222 3.2E-15 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CIG75_RS15975 7676d10d181db8ab826ebcca52fe93bd 453 SUPERFAMILY SSF102114 32 422 4.05E-71 T 28-03-2018 CIG75_RS15975 7676d10d181db8ab826ebcca52fe93bd 453 Gene3D G3DSA:3.20.20.70 15 349 2.4E-30 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CIG75_RS05335 aa745aed9756a0e078e7e26523a7ebed 358 Gene3D G3DSA:3.40.718.10 1 351 1.3E-78 T 28-03-2018 CIG75_RS05335 aa745aed9756a0e078e7e26523a7ebed 358 SMART SM01329 5 343 1.7E-65 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CIG75_RS05335 aa745aed9756a0e078e7e26523a7ebed 358 SUPERFAMILY SSF53659 2 347 1.02E-72 T 28-03-2018 CIG75_RS05335 aa745aed9756a0e078e7e26523a7ebed 358 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 5 343 1.6E-47 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CIG75_RS04550 49709a0941a5cb0dadc27d72e0afaa89 235 Gene3D G3DSA:3.40.50.10300 2 229 9.8E-49 T 28-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CIG75_RS04550 49709a0941a5cb0dadc27d72e0afaa89 235 SUPERFAMILY SSF102645 4 224 4.71E-45 T 28-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CIG75_RS04550 49709a0941a5cb0dadc27d72e0afaa89 235 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 4 186 6.9E-31 T 28-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CIG75_RS10675 2e77da9fffcf83037acdc486b16af693 161 SMART SM00529 63 154 0.0015 T 28-03-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 CIG75_RS10675 2e77da9fffcf83037acdc486b16af693 161 SMART SM00347 32 138 3.2E-17 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CIG75_RS10675 2e77da9fffcf83037acdc486b16af693 161 Gene3D G3DSA:1.10.10.10 1 161 5.5E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS10675 2e77da9fffcf83037acdc486b16af693 161 SUPERFAMILY SSF46785 17 155 3.57E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS10675 2e77da9fffcf83037acdc486b16af693 161 Pfam PF12802 MarR family 38 101 2.4E-11 T 28-03-2018 CIG75_RS10675 2e77da9fffcf83037acdc486b16af693 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 79 94 2.4E-12 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CIG75_RS10675 2e77da9fffcf83037acdc486b16af693 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 98 114 2.4E-12 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CIG75_RS10675 2e77da9fffcf83037acdc486b16af693 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 128 148 2.4E-12 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CIG75_RS10675 2e77da9fffcf83037acdc486b16af693 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 62 78 2.4E-12 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CIG75_RS13010 526dee7bb50ace902f9be289f72806f2 240 SMART SM00934 10 236 9.6E-84 T 28-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CIG75_RS13010 526dee7bb50ace902f9be289f72806f2 240 Gene3D G3DSA:3.20.20.70 6 240 3.0E-64 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CIG75_RS13010 526dee7bb50ace902f9be289f72806f2 240 Hamap MF_01200_B Orotidine 5'-phosphate decarboxylase [pyrF]. 8 240 35.019 T 28-03-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CIG75_RS13010 526dee7bb50ace902f9be289f72806f2 240 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 12 236 8.6E-56 T 28-03-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CIG75_RS13010 526dee7bb50ace902f9be289f72806f2 240 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 62 75 - T 28-03-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CIG75_RS13010 526dee7bb50ace902f9be289f72806f2 240 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 10 236 2.7E-46 T 28-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CIG75_RS13010 526dee7bb50ace902f9be289f72806f2 240 SUPERFAMILY SSF51366 9 239 6.77E-70 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CIG75_RS06965 967c0457c242cd663ebff8f4ea765723 142 Gene3D G3DSA:3.30.420.140 2 142 1.9E-49 T 28-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 CIG75_RS06965 967c0457c242cd663ebff8f4ea765723 142 Pfam PF03652 Holliday junction resolvase 5 136 3.3E-46 T 28-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 CIG75_RS06965 967c0457c242cd663ebff8f4ea765723 142 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 7 136 1.2E-48 T 28-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 CIG75_RS06965 967c0457c242cd663ebff8f4ea765723 142 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 4 139 27.388 T 28-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 CIG75_RS06965 967c0457c242cd663ebff8f4ea765723 142 SMART SM00732 4 104 4.5E-40 T 28-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 CIG75_RS06965 967c0457c242cd663ebff8f4ea765723 142 SUPERFAMILY SSF53098 4 139 3.03E-45 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CIG75_RS08530 4b91dbfcdcd63d32a4ed833a3b4f15f1 51 Pfam PF13072 Protein of unknown function (DUF3936) 3 26 2.1E-6 T 28-03-2018 IPR025177 Protein of unknown function DUF3936 CIG75_RS01900 368043c2fc718a5ebae3f0a9dc55fcf2 438 SUPERFAMILY SSF48452 115 320 1.08E-22 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS01900 368043c2fc718a5ebae3f0a9dc55fcf2 438 Pfam PF01381 Helix-turn-helix 10 63 9.6E-6 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS01900 368043c2fc718a5ebae3f0a9dc55fcf2 438 Gene3D G3DSA:1.25.40.10 67 169 4.0E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS01900 368043c2fc718a5ebae3f0a9dc55fcf2 438 Pfam PF13424 Tetratricopeptide repeat 196 267 1.3E-13 T 28-03-2018 CIG75_RS01900 368043c2fc718a5ebae3f0a9dc55fcf2 438 Gene3D G3DSA:1.10.150.200 226 281 8.8E-13 T 28-03-2018 CIG75_RS01900 368043c2fc718a5ebae3f0a9dc55fcf2 438 Gene3D G3DSA:1.10.150.200 282 329 2.3E-5 T 28-03-2018 CIG75_RS01900 368043c2fc718a5ebae3f0a9dc55fcf2 438 SMART SM00028 275 308 23.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS01900 368043c2fc718a5ebae3f0a9dc55fcf2 438 SMART SM00028 235 268 1.4E-4 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS01900 368043c2fc718a5ebae3f0a9dc55fcf2 438 SMART SM00028 394 427 140.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS01900 368043c2fc718a5ebae3f0a9dc55fcf2 438 SMART SM00028 195 228 0.86 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS01900 368043c2fc718a5ebae3f0a9dc55fcf2 438 SUPERFAMILY SSF47413 3 69 5.93E-10 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CIG75_RS01900 368043c2fc718a5ebae3f0a9dc55fcf2 438 Gene3D G3DSA:1.10.260.40 2 66 3.3E-9 T 28-03-2018 CIG75_RS01900 368043c2fc718a5ebae3f0a9dc55fcf2 438 SMART SM00530 9 63 2.7E-6 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS01900 368043c2fc718a5ebae3f0a9dc55fcf2 438 Gene3D G3DSA:1.25.40.10 330 436 3.5E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS01900 368043c2fc718a5ebae3f0a9dc55fcf2 438 Gene3D G3DSA:1.25.40.10 170 225 4.0E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS13175 31e182d56a0ac229e6079fc5a50612c1 167 Pfam PF05103 DivIVA protein 3 133 2.6E-51 T 28-03-2018 IPR007793 DivIVA family CIG75_RS13175 31e182d56a0ac229e6079fc5a50612c1 167 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 3 36 3.1E-17 T 28-03-2018 IPR019933 DivIVA domain CIG75_RS03590 5ecef61938cba3487ebe256d57622562 151 Gene3D G3DSA:2.40.30.70 1 146 4.2E-36 T 28-03-2018 IPR023370 TsaA-like domain CIG75_RS03590 5ecef61938cba3487ebe256d57622562 151 SUPERFAMILY SSF118196 1 148 3.14E-43 T 28-03-2018 IPR023370 TsaA-like domain CIG75_RS03590 5ecef61938cba3487ebe256d57622562 151 Pfam PF01980 Uncharacterised protein family UPF0066 22 128 1.5E-25 T 28-03-2018 IPR023370 TsaA-like domain CIG75_RS10405 a112a49b2aad824e0ad52c1919f77f77 523 Gene3D G3DSA:3.40.309.10 251 437 2.9E-69 T 28-03-2018 CIG75_RS10405 a112a49b2aad824e0ad52c1919f77f77 523 Gene3D G3DSA:3.40.605.10 2 250 3.6E-87 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CIG75_RS10405 a112a49b2aad824e0ad52c1919f77f77 523 SUPERFAMILY SSF53720 5 455 1.06E-151 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CIG75_RS10405 a112a49b2aad824e0ad52c1919f77f77 523 PIRSF PIRSF036492 14 497 2.3E-120 T 28-03-2018 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0004030|GO:0006081|GO:0055114 CIG75_RS10405 a112a49b2aad824e0ad52c1919f77f77 523 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 232 239 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CIG75_RS10405 a112a49b2aad824e0ad52c1919f77f77 523 Pfam PF00171 Aldehyde dehydrogenase family 5 450 2.4E-146 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CIG75_RS18590 550a0190c8d9f55f62b4b926f450f55d 86 Pfam PF01381 Helix-turn-helix 8 61 1.5E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS18590 550a0190c8d9f55f62b4b926f450f55d 86 SMART SM00530 7 61 4.9E-14 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS18590 550a0190c8d9f55f62b4b926f450f55d 86 Gene3D G3DSA:1.10.3100.10 1 86 2.0E-19 T 28-03-2018 IPR027910 YdiL-like domain CIG75_RS18590 550a0190c8d9f55f62b4b926f450f55d 86 SUPERFAMILY SSF47413 3 62 1.24E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CIG75_RS12075 4bb465b945c9f3e1278ef05a0e5821e9 151 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 105 140 2.4E-10 T 28-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain CIG75_RS12075 4bb465b945c9f3e1278ef05a0e5821e9 151 Pfam PF00460 Flagella basal body rod protein 7 34 4.1E-8 T 28-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 CIG75_RS12075 4bb465b945c9f3e1278ef05a0e5821e9 151 TIGRFAM TIGR01395 FlgC: flagellar basal-body rod protein FlgC 4 151 1.5E-47 T 28-03-2018 IPR006299 Flagellar basal-body rod protein FlgC GO:0030694|GO:0071973 CIG75_RS08615 7fcf7f1c608b978fa9d9d4ded52c5262 487 Gene3D G3DSA:1.10.287.950 191 272 7.5E-4 T 28-03-2018 CIG75_RS08615 7fcf7f1c608b978fa9d9d4ded52c5262 487 SMART SM00283 232 486 1.3E-25 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CIG75_RS08615 7fcf7f1c608b978fa9d9d4ded52c5262 487 Gene3D G3DSA:1.10.287.950 273 487 3.1E-39 T 28-03-2018 CIG75_RS08615 7fcf7f1c608b978fa9d9d4ded52c5262 487 SUPERFAMILY SSF58104 208 485 6.63E-48 T 28-03-2018 CIG75_RS08615 7fcf7f1c608b978fa9d9d4ded52c5262 487 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 308 453 1.5E-30 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CIG75_RS19950 ddc0155797df20fd09b4ab9938e6ff05 241 SUPERFAMILY SSF52540 1 224 1.3E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS19950 ddc0155797df20fd09b4ab9938e6ff05 241 SMART SM00382 26 211 8.2E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS19950 ddc0155797df20fd09b4ab9938e6ff05 241 Pfam PF00005 ABC transporter 18 162 1.4E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS19950 ddc0155797df20fd09b4ab9938e6ff05 241 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS19950 ddc0155797df20fd09b4ab9938e6ff05 241 Gene3D G3DSA:3.40.50.300 1 236 6.5E-67 T 28-03-2018 CIG75_RS18620 e390c5c3ddf08f804901fe8faad18bb9 396 Gene3D G3DSA:3.40.640.10 172 294 6.8E-44 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CIG75_RS18620 e390c5c3ddf08f804901fe8faad18bb9 396 Hamap MF_01689 Ornithine aminotransferase [rocD]. 4 396 63.967 T 28-03-2018 IPR034757 Ornithine aminotransferase, bacterial type GO:0004587 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922 CIG75_RS18620 e390c5c3ddf08f804901fe8faad18bb9 396 Gene3D G3DSA:3.90.1150.10 295 396 1.0E-19 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CIG75_RS18620 e390c5c3ddf08f804901fe8faad18bb9 396 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 12 396 36.764 T 28-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 CIG75_RS18620 e390c5c3ddf08f804901fe8faad18bb9 396 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 223 260 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CIG75_RS18620 e390c5c3ddf08f804901fe8faad18bb9 396 TIGRFAM TIGR01885 Orn_aminotrans: ornithine--oxo-acid transaminase 6 395 4.2E-166 T 28-03-2018 IPR010164 Ornithine aminotransferase GO:0004587 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CIG75_RS18620 e390c5c3ddf08f804901fe8faad18bb9 396 SUPERFAMILY SSF53383 3 395 2.04E-124 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CIG75_RS18620 e390c5c3ddf08f804901fe8faad18bb9 396 Gene3D G3DSA:3.90.1150.10 7 168 7.2E-40 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CIG75_RS18620 e390c5c3ddf08f804901fe8faad18bb9 396 Pfam PF00202 Aminotransferase class-III 15 394 1.1E-130 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CIG75_RS18620 e390c5c3ddf08f804901fe8faad18bb9 396 PIRSF PIRSF000521 2 160 7.2E-10 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CIG75_RS18620 e390c5c3ddf08f804901fe8faad18bb9 396 PIRSF PIRSF000521 175 396 3.4E-35 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CIG75_RS04180 699d6db104f947de3681a08977497f9b 109 SMART SM00418 10 94 3.3E-28 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CIG75_RS04180 699d6db104f947de3681a08977497f9b 109 SUPERFAMILY SSF46785 4 85 3.59E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS04180 699d6db104f947de3681a08977497f9b 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 44 59 6.1E-20 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CIG75_RS04180 699d6db104f947de3681a08977497f9b 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 59 74 6.1E-20 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CIG75_RS04180 699d6db104f947de3681a08977497f9b 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 12 27 6.1E-20 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CIG75_RS04180 699d6db104f947de3681a08977497f9b 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 31 42 6.1E-20 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CIG75_RS04180 699d6db104f947de3681a08977497f9b 109 Gene3D G3DSA:1.10.10.10 1 85 3.3E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS04180 699d6db104f947de3681a08977497f9b 109 Pfam PF01022 Bacterial regulatory protein, arsR family 17 62 2.7E-17 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CIG75_RS15495 d3a2bb9c5ae89621e17dfb431711b266 264 Pfam PF04607 Region found in RelA / SpoT proteins 37 162 1.2E-30 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 CIG75_RS15495 d3a2bb9c5ae89621e17dfb431711b266 264 Gene3D G3DSA:1.10.287.860 147 195 2.9E-16 T 28-03-2018 CIG75_RS15495 d3a2bb9c5ae89621e17dfb431711b266 264 Gene3D G3DSA:3.30.460.10 1 145 2.0E-32 T 28-03-2018 CIG75_RS15495 d3a2bb9c5ae89621e17dfb431711b266 264 SMART SM00954 37 164 2.2E-36 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 CIG75_RS15495 d3a2bb9c5ae89621e17dfb431711b266 264 SUPERFAMILY SSF81301 2 196 3.27E-46 T 28-03-2018 CIG75_RS00840 4299be98337eb1dcecda8496e5bb1d32 351 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 148 297 1.7E-9 T 28-03-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS00840 4299be98337eb1dcecda8496e5bb1d32 351 Gene3D G3DSA:3.40.50.720 2 153 4.5E-12 T 28-03-2018 CIG75_RS00840 4299be98337eb1dcecda8496e5bb1d32 351 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 5 122 2.5E-7 T 28-03-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CIG75_RS00840 4299be98337eb1dcecda8496e5bb1d32 351 Hamap MF_00559 Glyceraldehyde-3-phosphate dehydrogenase [gap]. 1 351 112.608 T 28-03-2018 IPR006436 Glyceraldehyde-3-phosphate dehydrogenase, type II GO:0005737|GO:0006096|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.59|KEGG: 00710+1.2.1.59 CIG75_RS00840 4299be98337eb1dcecda8496e5bb1d32 351 SUPERFAMILY SSF51735 5 161 3.28E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS00840 4299be98337eb1dcecda8496e5bb1d32 351 SMART SM00846 5 143 7.0E-4 T 28-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS00840 4299be98337eb1dcecda8496e5bb1d32 351 Gene3D G3DSA:3.30.360.10 154 305 1.0E-12 T 28-03-2018 CIG75_RS00840 4299be98337eb1dcecda8496e5bb1d32 351 PIRSF PIRSF000149 3 322 1.0E-41 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS00840 4299be98337eb1dcecda8496e5bb1d32 351 TIGRFAM TIGR01546 GAPDH-II_archae: glyceraldehyde-3-phosphate dehydrogenase, type II 7 337 4.6E-88 T 28-03-2018 IPR006436 Glyceraldehyde-3-phosphate dehydrogenase, type II GO:0005737|GO:0006096|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.59|KEGG: 00710+1.2.1.59 CIG75_RS00840 4299be98337eb1dcecda8496e5bb1d32 351 SUPERFAMILY SSF55347 143 299 3.74E-31 T 28-03-2018 CIG75_RS20365 c43db28490bb399993c600db26883561 311 Pfam PF01368 DHH family 16 147 1.2E-10 T 28-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CIG75_RS20365 c43db28490bb399993c600db26883561 311 Gene3D G3DSA:3.90.1640.10 14 185 7.4E-24 T 28-03-2018 CIG75_RS20365 c43db28490bb399993c600db26883561 311 SUPERFAMILY SSF64182 16 211 2.75E-29 T 28-03-2018 CIG75_RS13730 77a8add0200422856228d739dda9712b 545 SUPERFAMILY SSF53850 36 531 1.81E-124 T 28-03-2018 CIG75_RS13730 77a8add0200422856228d739dda9712b 545 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 84 464 1.2E-79 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CIG75_RS13730 77a8add0200422856228d739dda9712b 545 Gene3D G3DSA:3.90.76.10 63 173 1.4E-32 T 28-03-2018 CIG75_RS13730 77a8add0200422856228d739dda9712b 545 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 87 109 - T 28-03-2018 IPR023765 Solute-binding protein family 5, conserved site CIG75_RS13730 77a8add0200422856228d739dda9712b 545 Gene3D G3DSA:3.10.105.10 308 513 3.3E-47 T 28-03-2018 CIG75_RS13730 77a8add0200422856228d739dda9712b 545 PIRSF PIRSF002741 1 544 8.3E-109 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CIG75_RS13730 77a8add0200422856228d739dda9712b 545 Gene3D G3DSA:3.40.190.10 174 307 2.0E-35 T 28-03-2018 CIG75_RS11660 cc652127a926bee8a6a56d5144ef11a0 67 Pfam PF13693 Winged helix-turn-helix DNA-binding 11 64 8.5E-6 T 28-03-2018 CIG75_RS11660 cc652127a926bee8a6a56d5144ef11a0 67 Gene3D G3DSA:1.10.260.40 3 65 1.1E-6 T 28-03-2018 CIG75_RS11660 cc652127a926bee8a6a56d5144ef11a0 67 SUPERFAMILY SSF47413 7 61 4.29E-7 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CIG75_RS11660 cc652127a926bee8a6a56d5144ef11a0 67 SMART SM00530 6 61 0.0084 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS04695 795fd2ecb1695eaa4ceaed7e5ab8845f 328 ProSitePatterns PS01125 ROK family signature. 152 179 - T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CIG75_RS04695 795fd2ecb1695eaa4ceaed7e5ab8845f 328 SUPERFAMILY SSF53067 15 325 1.39E-66 T 28-03-2018 CIG75_RS04695 795fd2ecb1695eaa4ceaed7e5ab8845f 328 Gene3D G3DSA:3.30.420.40 8 137 1.2E-32 T 28-03-2018 CIG75_RS04695 795fd2ecb1695eaa4ceaed7e5ab8845f 328 Gene3D G3DSA:3.30.420.40 138 327 5.4E-59 T 28-03-2018 CIG75_RS04695 795fd2ecb1695eaa4ceaed7e5ab8845f 328 TIGRFAM TIGR00744 ROK_glcA_fam: ROK family protein (putative glucokinase) 19 323 4.4E-83 T 28-03-2018 IPR004654 Glucokinase ROK GO:0004340|GO:0005737|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 CIG75_RS04695 795fd2ecb1695eaa4ceaed7e5ab8845f 328 Pfam PF00480 ROK family 19 325 1.1E-70 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CIG75_RS04530 63a41107d791ee9049b423c75c66437c 105 Gene3D G3DSA:3.40.30.10 1 105 9.1E-10 T 28-03-2018 CIG75_RS04530 63a41107d791ee9049b423c75c66437c 105 SUPERFAMILY SSF52833 5 100 5.53E-15 T 28-03-2018 IPR012336 Thioredoxin-like fold CIG75_RS04530 63a41107d791ee9049b423c75c66437c 105 Pfam PF00085 Thioredoxin 17 86 1.2E-6 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 CIG75_RS13125 5bc3822b4881c659d76ccbdde1b82e2a 1198 ProSitePatterns PS00455 Putative AMP-binding domain signature. 361 372 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS13125 5bc3822b4881c659d76ccbdde1b82e2a 1198 SUPERFAMILY SSF47336 712 783 2.62E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS13125 5bc3822b4881c659d76ccbdde1b82e2a 1198 Gene3D G3DSA:2.30.38.10 521 599 5.6E-25 T 28-03-2018 CIG75_RS13125 5bc3822b4881c659d76ccbdde1b82e2a 1198 Pfam PF00501 AMP-binding enzyme 219 610 9.1E-99 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS13125 5bc3822b4881c659d76ccbdde1b82e2a 1198 Gene3D G3DSA:1.10.1200.10 726 800 1.2E-13 T 28-03-2018 CIG75_RS13125 5bc3822b4881c659d76ccbdde1b82e2a 1198 TIGRFAM TIGR01746 Thioester-redct: thioester reductase domain 819 1183 3.8E-69 T 28-03-2018 IPR010080 Thioester reductase-like domain CIG75_RS13125 5bc3822b4881c659d76ccbdde1b82e2a 1198 Gene3D G3DSA:3.30.300.30 605 725 4.3E-38 T 28-03-2018 CIG75_RS13125 5bc3822b4881c659d76ccbdde1b82e2a 1198 SUPERFAMILY SSF56801 197 732 2.35E-155 T 28-03-2018 CIG75_RS13125 5bc3822b4881c659d76ccbdde1b82e2a 1198 SUPERFAMILY SSF51735 1137 1176 2.7E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS13125 5bc3822b4881c659d76ccbdde1b82e2a 1198 SUPERFAMILY SSF51735 819 1109 2.7E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS13125 5bc3822b4881c659d76ccbdde1b82e2a 1198 Pfam PF07993 Male sterility protein 821 1063 9.7E-56 T 28-03-2018 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 CIG75_RS13125 5bc3822b4881c659d76ccbdde1b82e2a 1198 SUPERFAMILY SSF52777 9 188 3.89E-18 T 28-03-2018 CIG75_RS13125 5bc3822b4881c659d76ccbdde1b82e2a 1198 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 240 634 1.5E-130 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS13125 5bc3822b4881c659d76ccbdde1b82e2a 1198 PIRSF PIRSF001617 352 581 1.5E-12 T 28-03-2018 CIG75_RS13125 5bc3822b4881c659d76ccbdde1b82e2a 1198 PIRSF PIRSF001617 3 327 1.1E-18 T 28-03-2018 CIG75_RS13125 5bc3822b4881c659d76ccbdde1b82e2a 1198 PIRSF PIRSF001617 578 659 5.1E-20 T 28-03-2018 CIG75_RS13125 5bc3822b4881c659d76ccbdde1b82e2a 1198 PIRSF PIRSF001617 654 1194 4.4E-51 T 28-03-2018 CIG75_RS13125 5bc3822b4881c659d76ccbdde1b82e2a 1198 Pfam PF13193 AMP-binding enzyme C-terminal domain 618 691 1.3E-10 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS13125 5bc3822b4881c659d76ccbdde1b82e2a 1198 Gene3D G3DSA:3.40.50.720 813 1176 1.4E-32 T 28-03-2018 CIG75_RS13125 5bc3822b4881c659d76ccbdde1b82e2a 1198 Gene3D G3DSA:3.40.50.980 210 364 1.3E-48 T 28-03-2018 CIG75_RS13125 5bc3822b4881c659d76ccbdde1b82e2a 1198 Pfam PF00668 Condensation domain 117 198 3.7E-6 T 28-03-2018 IPR001242 Condensation domain CIG75_RS13125 5bc3822b4881c659d76ccbdde1b82e2a 1198 Gene3D G3DSA:3.40.50.980 365 511 2.6E-35 T 28-03-2018 CIG75_RS13125 5bc3822b4881c659d76ccbdde1b82e2a 1198 Pfam PF00550 Phosphopantetheine attachment site 721 783 5.0E-6 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS10385 db6eb5a581da54018d822b97cd59fb9d 293 Gene3D G3DSA:1.10.620.20 6 293 5.6E-60 T 28-03-2018 CIG75_RS10385 db6eb5a581da54018d822b97cd59fb9d 293 Pfam PF03405 Fatty acid desaturase 26 291 4.3E-45 T 28-03-2018 IPR005067 Fatty acid desaturase, type 2 GO:0006631|GO:0045300|GO:0055114 CIG75_RS10385 db6eb5a581da54018d822b97cd59fb9d 293 SUPERFAMILY SSF47240 6 292 2.3E-52 T 28-03-2018 IPR009078 Ferritin-like superfamily CIG75_RS00250 b9c4b47f1adff0f135633fde5ba9e953 459 Pfam PF10396 GTP-binding protein TrmE N-terminus 6 125 2.3E-37 T 28-03-2018 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 CIG75_RS00250 b9c4b47f1adff0f135633fde5ba9e953 459 Gene3D G3DSA:3.30.1360.120 1 126 1.7E-41 T 28-03-2018 CIG75_RS00250 b9c4b47f1adff0f135633fde5ba9e953 459 SUPERFAMILY SSF52540 209 375 9.56E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS00250 b9c4b47f1adff0f135633fde5ba9e953 459 SUPERFAMILY SSF52540 79 175 9.56E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS00250 b9c4b47f1adff0f135633fde5ba9e953 459 Pfam PF01926 50S ribosome-binding GTPase 224 336 3.8E-26 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CIG75_RS00250 b9c4b47f1adff0f135633fde5ba9e953 459 PRINTS PR00449 Transforming protein P21 ras signature 222 243 1.8E-5 T 28-03-2018 CIG75_RS00250 b9c4b47f1adff0f135633fde5ba9e953 459 PRINTS PR00449 Transforming protein P21 ras signature 326 339 1.8E-5 T 28-03-2018 CIG75_RS00250 b9c4b47f1adff0f135633fde5ba9e953 459 PRINTS PR00449 Transforming protein P21 ras signature 262 284 1.8E-5 T 28-03-2018 CIG75_RS00250 b9c4b47f1adff0f135633fde5ba9e953 459 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 11 459 1.6E-129 T 28-03-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 CIG75_RS00250 b9c4b47f1adff0f135633fde5ba9e953 459 Pfam PF12631 MnmE helical domain 128 456 1.6E-58 T 28-03-2018 IPR025867 MnmE, helical domain Reactome: R-HSA-6787450 CIG75_RS00250 b9c4b47f1adff0f135633fde5ba9e953 459 Gene3D G3DSA:1.20.120.430 287 459 8.2E-36 T 28-03-2018 CIG75_RS00250 b9c4b47f1adff0f135633fde5ba9e953 459 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 5 459 34.513 T 28-03-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 CIG75_RS00250 b9c4b47f1adff0f135633fde5ba9e953 459 Gene3D G3DSA:1.20.120.430 127 286 1.2E-27 T 28-03-2018 CIG75_RS00250 b9c4b47f1adff0f135633fde5ba9e953 459 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 223 373 3.6E-27 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CIG75_RS11310 60686c1472cfa31e3bc5e7ae08754e5f 171 Gene3D G3DSA:3.30.530.20 2 171 2.9E-29 T 28-03-2018 IPR023393 START-like domain CIG75_RS11310 60686c1472cfa31e3bc5e7ae08754e5f 171 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 18 165 3.5E-26 T 28-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CIG75_RS11310 60686c1472cfa31e3bc5e7ae08754e5f 171 SUPERFAMILY SSF55961 6 167 4.87E-41 T 28-03-2018 CIG75_RS06880 b63d4723f8885d3787406f395dc03f34 349 Gene3D G3DSA:3.40.640.10 1 248 3.5E-48 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CIG75_RS06880 b63d4723f8885d3787406f395dc03f34 349 PIRSF PIRSF017617 1 349 1.1E-123 T 28-03-2018 IPR023603 Threonine aldolase CIG75_RS06880 b63d4723f8885d3787406f395dc03f34 349 Gene3D G3DSA:3.90.1150.10 249 346 6.2E-25 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CIG75_RS06880 b63d4723f8885d3787406f395dc03f34 349 Pfam PF01212 Beta-eliminating lyase 4 288 2.5E-90 T 28-03-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 CIG75_RS06880 b63d4723f8885d3787406f395dc03f34 349 SUPERFAMILY SSF53383 3 344 5.05E-110 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CIG75_RS01155 599ac0d877f3f965b1cdd46f97a182a1 816 Gene3D G3DSA:3.40.50.300 3 163 6.7E-19 T 28-03-2018 CIG75_RS01155 599ac0d877f3f965b1cdd46f97a182a1 816 TIGRFAM TIGR01970 DEAH_box_HrpB: ATP-dependent helicase HrpB 4 815 0.0 T 28-03-2018 IPR010225 ATP-dependent helicase HrpB GO:0008026 CIG75_RS01155 599ac0d877f3f965b1cdd46f97a182a1 816 Pfam PF08482 ATP-dependent helicase C-terminal 670 802 6.0E-56 T 28-03-2018 IPR013689 ATP-dependent RNA helicase HrpB, C-terminal CIG75_RS01155 599ac0d877f3f965b1cdd46f97a182a1 816 SUPERFAMILY SSF52540 20 341 5.64E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS01155 599ac0d877f3f965b1cdd46f97a182a1 816 Pfam PF00271 Helicase conserved C-terminal domain 206 329 6.8E-13 T 28-03-2018 IPR001650 Helicase, C-terminal CIG75_RS01155 599ac0d877f3f965b1cdd46f97a182a1 816 SMART SM00847 390 479 3.4E-17 T 28-03-2018 IPR007502 Helicase-associated domain GO:0004386 CIG75_RS01155 599ac0d877f3f965b1cdd46f97a182a1 816 Gene3D G3DSA:3.40.50.300 181 350 7.8E-47 T 28-03-2018 CIG75_RS01155 599ac0d877f3f965b1cdd46f97a182a1 816 Pfam PF04408 Helicase associated domain (HA2) 391 458 3.3E-13 T 28-03-2018 IPR007502 Helicase-associated domain GO:0004386 CIG75_RS01155 599ac0d877f3f965b1cdd46f97a182a1 816 Pfam PF00270 DEAD/DEAH box helicase 17 167 1.6E-6 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CIG75_RS01155 599ac0d877f3f965b1cdd46f97a182a1 816 SMART SM00490 227 330 9.5E-13 T 28-03-2018 IPR001650 Helicase, C-terminal CIG75_RS01155 599ac0d877f3f965b1cdd46f97a182a1 816 SMART SM00487 5 187 7.3E-13 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CIG75_RS01155 599ac0d877f3f965b1cdd46f97a182a1 816 PIRSF PIRSF005496 1 816 0.0 T 28-03-2018 CIG75_RS06500 06bd8ff01c11a52bbb9ad0443bbfb344 311 Pfam PF04392 ABC transporter substrate binding protein 13 302 1.3E-90 T 28-03-2018 IPR007487 ABC transporter, substrate-binding protein CIG75_RS06500 06bd8ff01c11a52bbb9ad0443bbfb344 311 Gene3D G3DSA:3.40.50.2300 138 275 1.8E-16 T 28-03-2018 CIG75_RS06500 06bd8ff01c11a52bbb9ad0443bbfb344 311 Gene3D G3DSA:3.40.50.2300 10 137 2.3E-23 T 28-03-2018 CIG75_RS06500 06bd8ff01c11a52bbb9ad0443bbfb344 311 SUPERFAMILY SSF53822 12 183 2.19E-14 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CIG75_RS18685 c0b7e595c73077785b00019b56738f91 239 Gene3D G3DSA:3.30.200.20 2 94 3.2E-28 T 28-03-2018 CIG75_RS18685 c0b7e595c73077785b00019b56738f91 239 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 2 235 9.5E-73 T 28-03-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 CIG75_RS18685 c0b7e595c73077785b00019b56738f91 239 SUPERFAMILY SSF56104 4 237 1.86E-83 T 28-03-2018 CIG75_RS18685 c0b7e595c73077785b00019b56738f91 239 Pfam PF01259 SAICAR synthetase 8 233 4.4E-68 T 28-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CIG75_RS18685 c0b7e595c73077785b00019b56738f91 239 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 5 236 32.366 T 28-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CIG75_RS18685 c0b7e595c73077785b00019b56738f91 239 Gene3D G3DSA:3.30.470.20 95 222 5.9E-48 T 28-03-2018 CIG75_RS18685 c0b7e595c73077785b00019b56738f91 239 ProSitePatterns PS01057 SAICAR synthetase signature 1. 87 101 - T 28-03-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CIG75_RS18685 c0b7e595c73077785b00019b56738f91 239 ProSitePatterns PS01058 SAICAR synthetase signature 2. 174 182 - T 28-03-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CIG75_RS01615 8d2e15acb6da318a2e372f6f3238b675 260 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 259 1.5E-76 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CIG75_RS01615 8d2e15acb6da318a2e372f6f3238b675 260 Gene3D G3DSA:1.10.12.10 221 258 4.8E-22 T 28-03-2018 IPR014748 Crontonase, C-terminal CIG75_RS01615 8d2e15acb6da318a2e372f6f3238b675 260 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 101 121 - T 28-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CIG75_RS01615 8d2e15acb6da318a2e372f6f3238b675 260 Gene3D G3DSA:3.90.226.10 2 220 7.5E-80 T 28-03-2018 CIG75_RS01615 8d2e15acb6da318a2e372f6f3238b675 260 SUPERFAMILY SSF52096 1 260 1.54E-95 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CIG75_RS01370 6ae617dab14105746ee0b41920993ac2 281 SMART SM00450 6 132 5.8E-19 T 28-03-2018 IPR001763 Rhodanese-like domain CIG75_RS01370 6ae617dab14105746ee0b41920993ac2 281 SMART SM00450 155 272 2.0E-19 T 28-03-2018 IPR001763 Rhodanese-like domain CIG75_RS01370 6ae617dab14105746ee0b41920993ac2 281 Gene3D G3DSA:3.40.250.10 151 281 3.0E-29 T 28-03-2018 IPR001763 Rhodanese-like domain CIG75_RS01370 6ae617dab14105746ee0b41920993ac2 281 Gene3D G3DSA:3.40.250.10 1 150 1.4E-28 T 28-03-2018 IPR001763 Rhodanese-like domain CIG75_RS01370 6ae617dab14105746ee0b41920993ac2 281 Pfam PF00581 Rhodanese-like domain 158 268 1.9E-15 T 28-03-2018 IPR001763 Rhodanese-like domain CIG75_RS01370 6ae617dab14105746ee0b41920993ac2 281 Pfam PF00581 Rhodanese-like domain 7 128 5.8E-16 T 28-03-2018 IPR001763 Rhodanese-like domain CIG75_RS01370 6ae617dab14105746ee0b41920993ac2 281 SUPERFAMILY SSF52821 151 276 7.33E-34 T 28-03-2018 IPR001763 Rhodanese-like domain CIG75_RS01370 6ae617dab14105746ee0b41920993ac2 281 SUPERFAMILY SSF52821 3 153 8.25E-39 T 28-03-2018 IPR001763 Rhodanese-like domain CIG75_RS19945 7be0932952448a37ca0e8e704c7a801c 398 Pfam PF12698 ABC-2 family transporter protein 22 381 1.9E-34 T 28-03-2018 CIG75_RS19945 7be0932952448a37ca0e8e704c7a801c 398 Gene3D G3DSA:3.40.1710.10 54 195 2.6E-14 T 28-03-2018 CIG75_RS00225 15872d62eadb843a4c73b5f90253fe3d 44 ProSitePatterns PS00784 Ribosomal protein L34 signature. 2 21 - T 28-03-2018 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS00225 15872d62eadb843a4c73b5f90253fe3d 44 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 1 44 6.1E-20 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS00225 15872d62eadb843a4c73b5f90253fe3d 44 Pfam PF00468 Ribosomal protein L34 1 44 1.5E-22 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS00225 15872d62eadb843a4c73b5f90253fe3d 44 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 1 44 15.915 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS00225 15872d62eadb843a4c73b5f90253fe3d 44 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 1 26 1.0E-5 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS02175 62c9eefa39b618fb76fd2a78148af313 378 TIGRFAM TIGR03609 S_layer_CsaB: polysaccharide pyruvyl transferase CsaB 3 314 1.7E-86 T 28-03-2018 IPR019896 Polysaccharide pyruvyl transferase, CsaB CIG75_RS02175 62c9eefa39b618fb76fd2a78148af313 378 SUPERFAMILY SSF53756 11 302 1.41E-9 T 28-03-2018 CIG75_RS02175 62c9eefa39b618fb76fd2a78148af313 378 Pfam PF04230 Polysaccharide pyruvyl transferase 14 301 2.4E-54 T 28-03-2018 IPR007345 Polysaccharide pyruvyl transferase CIG75_RS02175 62c9eefa39b618fb76fd2a78148af313 378 Gene3D G3DSA:3.40.50.2000 178 365 8.1E-11 T 28-03-2018 CIG75_RS06985 ffce4d35c6876135e57899464eed5d20 208 SUPERFAMILY SSF53335 29 208 4.91E-44 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CIG75_RS06985 ffce4d35c6876135e57899464eed5d20 208 Gene3D G3DSA:3.40.50.150 1 208 5.4E-35 T 28-03-2018 CIG75_RS06985 ffce4d35c6876135e57899464eed5d20 208 Pfam PF01596 O-methyltransferase 39 207 1.5E-30 T 28-03-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 CIG75_RS04940 2dad6a6a4d8a1003db5588483c5f089c 152 Pfam PF00578 AhpC/TSA family 4 127 2.5E-26 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CIG75_RS04940 2dad6a6a4d8a1003db5588483c5f089c 152 SUPERFAMILY SSF52833 1 142 1.58E-32 T 28-03-2018 IPR012336 Thioredoxin-like fold CIG75_RS04940 2dad6a6a4d8a1003db5588483c5f089c 152 Gene3D G3DSA:3.40.30.10 1 151 4.7E-28 T 28-03-2018 CIG75_RS04940 2dad6a6a4d8a1003db5588483c5f089c 152 PIRSF PIRSF000239 1 142 3.5E-20 T 28-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CIG75_RS10150 4fb8fc6b40f334ea6a0ade34184ca56a 286 Gene3D G3DSA:1.10.3470.10 1 277 9.3E-44 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CIG75_RS10150 4fb8fc6b40f334ea6a0ade34184ca56a 286 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 274 6.0E-41 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CIG75_RS05720 508c4701f276e52814f98d8da171cf45 809 Pfam PF00483 Nucleotidyl transferase 2 227 2.9E-50 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CIG75_RS05720 508c4701f276e52814f98d8da171cf45 809 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 250 282 7.1E-5 T 28-03-2018 IPR001451 Hexapeptide repeat CIG75_RS05720 508c4701f276e52814f98d8da171cf45 809 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 382 514 4.7E-18 T 28-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CIG75_RS05720 508c4701f276e52814f98d8da171cf45 809 SUPERFAMILY SSF53448 1 235 1.24E-75 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CIG75_RS05720 508c4701f276e52814f98d8da171cf45 809 SUPERFAMILY SSF53448 263 275 1.24E-75 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CIG75_RS05720 508c4701f276e52814f98d8da171cf45 809 SUPERFAMILY SSF51161 241 382 6.65E-25 T 28-03-2018 IPR011004 Trimeric LpxA-like CIG75_RS05720 508c4701f276e52814f98d8da171cf45 809 Gene3D G3DSA:2.160.10.10 233 372 2.8E-23 T 28-03-2018 CIG75_RS05720 508c4701f276e52814f98d8da171cf45 809 SUPERFAMILY SSF53738 376 519 3.41E-22 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CIG75_RS05720 508c4701f276e52814f98d8da171cf45 809 Gene3D G3DSA:3.90.550.10 1 232 5.7E-62 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CIG75_RS05720 508c4701f276e52814f98d8da171cf45 809 Gene3D G3DSA:3.40.120.10 380 527 3.1E-20 T 28-03-2018 CIG75_RS05720 508c4701f276e52814f98d8da171cf45 809 Gene3D G3DSA:3.30.310.50 719 805 3.7E-8 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CIG75_RS05720 508c4701f276e52814f98d8da171cf45 809 SUPERFAMILY SSF55957 716 800 1.02E-14 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CIG75_RS08105 566cd9bf35a11eb1b2be3e40ecee284e 299 Gene3D G3DSA:3.10.580.10 81 290 1.5E-4 T 28-03-2018 CIG75_RS08105 566cd9bf35a11eb1b2be3e40ecee284e 299 Pfam PF02163 Peptidase family M50 35 107 7.1E-7 T 28-03-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889|Reactome: R-MMU-8963889 CIG75_RS03295 0c40a3ed032416501cd15a22623850f8 430 Pfam PF01411 tRNA synthetases class II (A) 193 384 1.7E-20 T 28-03-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 CIG75_RS03295 0c40a3ed032416501cd15a22623850f8 430 Pfam PF01411 tRNA synthetases class II (A) 5 144 5.6E-5 T 28-03-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 CIG75_RS03295 0c40a3ed032416501cd15a22623850f8 430 SUPERFAMILY SSF55681 4 213 6.96E-9 T 28-03-2018 CIG75_RS03295 0c40a3ed032416501cd15a22623850f8 430 SUPERFAMILY SSF101353 214 383 1.7E-19 T 28-03-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 CIG75_RS03295 0c40a3ed032416501cd15a22623850f8 430 Gene3D G3DSA:3.30.930.10 1 151 2.4E-11 T 28-03-2018 CIG75_RS13705 0d55306758603e1e0ccc0dad06367d6f 259 Pfam PF12697 Alpha/beta hydrolase family 28 247 1.9E-12 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CIG75_RS13705 0d55306758603e1e0ccc0dad06367d6f 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 199 213 6.7E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CIG75_RS13705 0d55306758603e1e0ccc0dad06367d6f 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 96 109 6.7E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CIG75_RS13705 0d55306758603e1e0ccc0dad06367d6f 259 Gene3D G3DSA:3.40.50.1820 6 256 1.3E-34 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS13705 0d55306758603e1e0ccc0dad06367d6f 259 SUPERFAMILY SSF53474 17 254 1.82E-46 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS13645 c858c0a3bc3ed33e18f1598ec1fd7c9d 258 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 35 254 2.3E-62 T 28-03-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689|GO:0030288 CIG75_RS13645 c858c0a3bc3ed33e18f1598ec1fd7c9d 258 SUPERFAMILY SSF53850 28 255 7.94E-69 T 28-03-2018 CIG75_RS13645 c858c0a3bc3ed33e18f1598ec1fd7c9d 258 PIRSF PIRSF004846 1 258 2.6E-77 T 28-03-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689|GO:0030288 CIG75_RS13645 c858c0a3bc3ed33e18f1598ec1fd7c9d 258 Gene3D G3DSA:3.40.190.10 22 122 2.3E-11 T 28-03-2018 CIG75_RS13645 c858c0a3bc3ed33e18f1598ec1fd7c9d 258 Pfam PF13531 Bacterial extracellular solute-binding protein 33 255 8.6E-52 T 28-03-2018 CIG75_RS13645 c858c0a3bc3ed33e18f1598ec1fd7c9d 258 Gene3D G3DSA:3.40.190.10 123 218 5.2E-37 T 28-03-2018 CIG75_RS09850 b309dcd5d437be81065112709878b04f 168 SUPERFAMILY SSF52518 4 165 4.77E-14 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CIG75_RS09850 b309dcd5d437be81065112709878b04f 168 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 3 166 2.9E-9 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CIG75_RS09850 b309dcd5d437be81065112709878b04f 168 Gene3D G3DSA:3.40.50.970 2 168 4.3E-19 T 28-03-2018 CIG75_RS02655 0541a5dd08c4d7512711f74f38cd7b25 256 SUPERFAMILY SSF52467 33 189 1.04E-8 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CIG75_RS02655 0541a5dd08c4d7512711f74f38cd7b25 256 Gene3D G3DSA:3.40.50.1220 33 210 1.1E-4 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CIG75_RS02655 0541a5dd08c4d7512711f74f38cd7b25 256 Pfam PF13289 SIR2-like domain 84 226 2.4E-23 T 28-03-2018 CIG75_RS06095 855f657eadb20457bb8a60af6c777dca 271 PIRSF PIRSF006661 1 271 5.3E-96 T 28-03-2018 IPR005232 Lactate racemization operon protein LarE CIG75_RS06095 855f657eadb20457bb8a60af6c777dca 271 SUPERFAMILY SSF52402 17 220 3.31E-34 T 28-03-2018 CIG75_RS06095 855f657eadb20457bb8a60af6c777dca 271 Pfam PF02540 NAD synthase 16 82 6.2E-8 T 28-03-2018 IPR022310 NAD/GMP synthase CIG75_RS06095 855f657eadb20457bb8a60af6c777dca 271 TIGRFAM TIGR00268 TIGR00268: TIGR00268 family protein 6 259 1.6E-80 T 28-03-2018 IPR005232 Lactate racemization operon protein LarE CIG75_RS06095 855f657eadb20457bb8a60af6c777dca 271 Gene3D G3DSA:3.40.50.620 3 269 3.4E-26 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CIG75_RS14065 5929a0dbacd24da1e5d5409c18cac43d 197 SUPERFAMILY SSF52096 10 195 3.11E-74 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CIG75_RS14065 5929a0dbacd24da1e5d5409c18cac43d 197 Pfam PF00574 Clp protease 12 192 2.6E-87 T 28-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA CIG75_RS14065 5929a0dbacd24da1e5d5409c18cac43d 197 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 1 191 2.9E-102 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CIG75_RS14065 5929a0dbacd24da1e5d5409c18cac43d 197 Gene3D G3DSA:3.90.226.10 2 194 1.6E-48 T 28-03-2018 CIG75_RS14065 5929a0dbacd24da1e5d5409c18cac43d 197 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 3 193 44.665 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CIG75_RS14065 5929a0dbacd24da1e5d5409c18cac43d 197 PRINTS PR00127 Clp protease catalytic subunit P signature 90 107 9.0E-52 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CIG75_RS14065 5929a0dbacd24da1e5d5409c18cac43d 197 PRINTS PR00127 Clp protease catalytic subunit P signature 168 187 9.0E-52 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CIG75_RS14065 5929a0dbacd24da1e5d5409c18cac43d 197 PRINTS PR00127 Clp protease catalytic subunit P signature 19 34 9.0E-52 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CIG75_RS14065 5929a0dbacd24da1e5d5409c18cac43d 197 PRINTS PR00127 Clp protease catalytic subunit P signature 59 79 9.0E-52 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CIG75_RS14065 5929a0dbacd24da1e5d5409c18cac43d 197 PRINTS PR00127 Clp protease catalytic subunit P signature 111 130 9.0E-52 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CIG75_RS14065 5929a0dbacd24da1e5d5409c18cac43d 197 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 112 125 - T 28-03-2018 IPR033135 ClpP, histidine active site CIG75_RS14065 5929a0dbacd24da1e5d5409c18cac43d 197 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 90 101 - T 28-03-2018 IPR018215 ClpP, Ser active site CIG75_RS00390 aca14c02e89a3787b50d2015c9dc9aaf 368 Gene3D G3DSA:1.20.1170.10 38 356 1.7E-23 T 28-03-2018 CIG75_RS00390 aca14c02e89a3787b50d2015c9dc9aaf 368 SUPERFAMILY SSF58100 48 360 1.75E-31 T 28-03-2018 CIG75_RS00390 aca14c02e89a3787b50d2015c9dc9aaf 368 Pfam PF05791 Bacillus haemolytic enterotoxin (HBL) 58 193 6.7E-11 T 28-03-2018 IPR008414 Hemolysin BL-binding component GO:0009405|GO:0016020 CIG75_RS11855 7899b7139e72bb914151ba79d6f5369e 362 Gene3D G3DSA:3.20.20.120 20 190 6.4E-21 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CIG75_RS11855 7899b7139e72bb914151ba79d6f5369e 362 Pfam PF04551 GcpE protein 8 349 5.1E-142 T 28-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 CIG75_RS11855 7899b7139e72bb914151ba79d6f5369e 362 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 5 348 3.6E-133 T 28-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 CIG75_RS11855 7899b7139e72bb914151ba79d6f5369e 362 PIRSF PIRSF004640 1 358 2.0E-154 T 28-03-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 CIG75_RS11855 7899b7139e72bb914151ba79d6f5369e 362 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 3 353 35.259 T 28-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 CIG75_RS11855 7899b7139e72bb914151ba79d6f5369e 362 SUPERFAMILY SSF56014 260 349 8.87E-14 T 28-03-2018 CIG75_RS11855 7899b7139e72bb914151ba79d6f5369e 362 SUPERFAMILY SSF51717 31 219 6.83E-17 T 28-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CIG75_RS18110 07e14855bcdc04acce94d5eebd5a46fe 81 Gene3D G3DSA:1.10.3910.10 1 67 6.8E-12 T 28-03-2018 CIG75_RS18110 07e14855bcdc04acce94d5eebd5a46fe 81 SUPERFAMILY SSF140683 2 64 4.45E-6 T 28-03-2018 CIG75_RS17900 4510f4da1e69bf90f5693fe41cfe18d5 225 Pfam PF05495 CHY zinc finger 135 208 3.7E-11 T 28-03-2018 IPR008913 Zinc finger, CHY-type GO:0008270 Reactome: R-HSA-110320|Reactome: R-HSA-983168 CIG75_RS17900 4510f4da1e69bf90f5693fe41cfe18d5 225 SUPERFAMILY SSF161219 125 211 1.7E-16 T 28-03-2018 CIG75_RS17900 4510f4da1e69bf90f5693fe41cfe18d5 225 Pfam PF06935 Protein of unknown function (DUF1284) 2 102 1.4E-21 T 28-03-2018 IPR009702 Protein of unknown function DUF1284 CIG75_RS13570 cc234b6bdb34a5fdf776db2965a3cbdb 509 SUPERFAMILY SSF52096 211 489 1.57E-81 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CIG75_RS13570 cc234b6bdb34a5fdf776db2965a3cbdb 509 SUPERFAMILY SSF52096 6 249 6.15E-69 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CIG75_RS13570 cc234b6bdb34a5fdf776db2965a3cbdb 509 Gene3D G3DSA:3.90.226.10 5 237 1.0E-65 T 28-03-2018 CIG75_RS13570 cc234b6bdb34a5fdf776db2965a3cbdb 509 Pfam PF01039 Carboxyl transferase domain 26 505 1.6E-154 T 28-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 CIG75_RS13570 cc234b6bdb34a5fdf776db2965a3cbdb 509 Gene3D G3DSA:3.90.226.10 238 506 5.6E-66 T 28-03-2018 CIG75_RS09270 b54d9617df02d6c5791e03f79b8982f8 460 Pfam PF07687 Peptidase dimerisation domain 256 357 1.9E-4 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CIG75_RS09270 b54d9617df02d6c5791e03f79b8982f8 460 SUPERFAMILY SSF55031 182 366 7.5E-35 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CIG75_RS09270 b54d9617df02d6c5791e03f79b8982f8 460 Pfam PF01546 Peptidase family M20/M25/M40 80 456 2.9E-31 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CIG75_RS09270 b54d9617df02d6c5791e03f79b8982f8 460 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 78 87 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CIG75_RS09270 b54d9617df02d6c5791e03f79b8982f8 460 TIGRFAM TIGR01887 dipeptidaselike: putative dipeptidase 10 455 4.8E-147 T 28-03-2018 IPR010964 Peptidase M20A, peptidase V-related GO:0008270|GO:0016805 CIG75_RS09270 b54d9617df02d6c5791e03f79b8982f8 460 SUPERFAMILY SSF53187 4 182 6.83E-69 T 28-03-2018 CIG75_RS09270 b54d9617df02d6c5791e03f79b8982f8 460 SUPERFAMILY SSF53187 377 459 6.83E-69 T 28-03-2018 CIG75_RS09270 b54d9617df02d6c5791e03f79b8982f8 460 Gene3D G3DSA:3.40.630.10 1 460 1.2E-54 T 28-03-2018 CIG75_RS09270 b54d9617df02d6c5791e03f79b8982f8 460 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 112 151 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CIG75_RS00575 dbc3ba47e5e1871f272d901498b2fe88 159 TIGRFAM TIGR00246 tRNA_RlmH_YbeA: rRNA large subunit m3Psi methyltransferase RlmH 2 159 3.9E-53 T 28-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CIG75_RS00575 dbc3ba47e5e1871f272d901498b2fe88 159 PIRSF PIRSF004505 1 159 5.1E-53 T 28-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CIG75_RS00575 dbc3ba47e5e1871f272d901498b2fe88 159 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 1 159 30.168 T 28-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CIG75_RS00575 dbc3ba47e5e1871f272d901498b2fe88 159 SUPERFAMILY SSF75217 1 157 8.5E-55 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CIG75_RS00575 dbc3ba47e5e1871f272d901498b2fe88 159 Pfam PF02590 Predicted SPOUT methyltransferase 1 158 9.2E-59 T 28-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CIG75_RS00575 dbc3ba47e5e1871f272d901498b2fe88 159 Gene3D G3DSA:3.40.1280.10 1 159 1.6E-60 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CIG75_RS15220 8c7b1f247896ef2cc33a8b5f970451a2 299 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 131 155 2.2E-28 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CIG75_RS15220 8c7b1f247896ef2cc33a8b5f970451a2 299 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 183 199 2.2E-28 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CIG75_RS15220 8c7b1f247896ef2cc33a8b5f970451a2 299 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 254 272 2.2E-28 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CIG75_RS15220 8c7b1f247896ef2cc33a8b5f970451a2 299 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 220 241 2.2E-28 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CIG75_RS15220 8c7b1f247896ef2cc33a8b5f970451a2 299 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 25 40 2.2E-28 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CIG75_RS15220 8c7b1f247896ef2cc33a8b5f970451a2 299 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 94 102 2.2E-28 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CIG75_RS15220 8c7b1f247896ef2cc33a8b5f970451a2 299 Gene3D G3DSA:3.50.50.60 139 290 1.2E-25 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS15220 8c7b1f247896ef2cc33a8b5f970451a2 299 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 218 234 4.9E-23 T 28-03-2018 CIG75_RS15220 8c7b1f247896ef2cc33a8b5f970451a2 299 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 244 266 4.9E-23 T 28-03-2018 CIG75_RS15220 8c7b1f247896ef2cc33a8b5f970451a2 299 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 93 111 4.9E-23 T 28-03-2018 CIG75_RS15220 8c7b1f247896ef2cc33a8b5f970451a2 299 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 135 153 4.9E-23 T 28-03-2018 CIG75_RS15220 8c7b1f247896ef2cc33a8b5f970451a2 299 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 40 281 1.3E-32 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS15220 8c7b1f247896ef2cc33a8b5f970451a2 299 SUPERFAMILY SSF51905 1 288 2.85E-34 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS15220 8c7b1f247896ef2cc33a8b5f970451a2 299 Gene3D G3DSA:3.50.50.60 1 138 3.8E-17 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS19695 f0518c8907a19ad9b357ab84097e39ab 65 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 60 3.4E-26 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CIG75_RS19695 f0518c8907a19ad9b357ab84097e39ab 65 Gene3D G3DSA:1.10.287.310 1 63 1.2E-27 T 28-03-2018 CIG75_RS19695 f0518c8907a19ad9b357ab84097e39ab 65 Pfam PF00831 Ribosomal L29 protein 4 60 1.1E-27 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CIG75_RS19695 f0518c8907a19ad9b357ab84097e39ab 65 ProSitePatterns PS00579 Ribosomal protein L29 signature. 39 53 - T 28-03-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CIG75_RS19695 f0518c8907a19ad9b357ab84097e39ab 65 SUPERFAMILY SSF46561 1 63 1.11E-24 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CIG75_RS19695 f0518c8907a19ad9b357ab84097e39ab 65 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 60 18.806 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CIG75_RS04105 e55831f2fd5ce3670f5f28cd43deaa66 373 SUPERFAMILY SSF55073 215 371 6.75E-48 T 28-03-2018 IPR029787 Nucleotide cyclase CIG75_RS04105 e55831f2fd5ce3670f5f28cd43deaa66 373 SMART SM00267 199 372 2.7E-58 T 28-03-2018 IPR000160 GGDEF domain CIG75_RS04105 e55831f2fd5ce3670f5f28cd43deaa66 373 Gene3D G3DSA:3.30.70.270 201 373 2.0E-55 T 28-03-2018 CIG75_RS04105 e55831f2fd5ce3670f5f28cd43deaa66 373 Pfam PF07694 5TMR of 5TMR-LYT 46 188 5.4E-10 T 28-03-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 CIG75_RS04105 e55831f2fd5ce3670f5f28cd43deaa66 373 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 206 372 1.1E-54 T 28-03-2018 IPR000160 GGDEF domain CIG75_RS04105 e55831f2fd5ce3670f5f28cd43deaa66 373 Pfam PF00990 Diguanylate cyclase, GGDEF domain 210 368 1.6E-45 T 28-03-2018 IPR000160 GGDEF domain CIG75_RS13040 1514c9b048a277bb30b7a3a26b0e0cb1 319 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 1 304 35.536 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CIG75_RS13040 1514c9b048a277bb30b7a3a26b0e0cb1 319 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 3 301 9.5E-107 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CIG75_RS13040 1514c9b048a277bb30b7a3a26b0e0cb1 319 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 151 300 2.4E-32 T 28-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 CIG75_RS13040 1514c9b048a277bb30b7a3a26b0e0cb1 319 Gene3D G3DSA:3.40.50.1370 1 143 1.4E-50 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CIG75_RS13040 1514c9b048a277bb30b7a3a26b0e0cb1 319 PRINTS PR00101 Aspartate carbamoyltransferase signature 36 58 2.4E-40 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CIG75_RS13040 1514c9b048a277bb30b7a3a26b0e0cb1 319 PRINTS PR00101 Aspartate carbamoyltransferase signature 130 147 2.4E-40 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CIG75_RS13040 1514c9b048a277bb30b7a3a26b0e0cb1 319 PRINTS PR00101 Aspartate carbamoyltransferase signature 283 297 2.4E-40 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CIG75_RS13040 1514c9b048a277bb30b7a3a26b0e0cb1 319 PRINTS PR00101 Aspartate carbamoyltransferase signature 261 266 2.4E-40 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CIG75_RS13040 1514c9b048a277bb30b7a3a26b0e0cb1 319 PRINTS PR00101 Aspartate carbamoyltransferase signature 222 231 2.4E-40 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CIG75_RS13040 1514c9b048a277bb30b7a3a26b0e0cb1 319 PRINTS PR00101 Aspartate carbamoyltransferase signature 76 85 2.4E-40 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CIG75_RS13040 1514c9b048a277bb30b7a3a26b0e0cb1 319 SUPERFAMILY SSF53671 2 304 2.49E-98 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CIG75_RS13040 1514c9b048a277bb30b7a3a26b0e0cb1 319 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 3 143 4.7E-46 T 28-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 CIG75_RS13040 1514c9b048a277bb30b7a3a26b0e0cb1 319 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 46 65 7.0E-26 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CIG75_RS13040 1514c9b048a277bb30b7a3a26b0e0cb1 319 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 131 142 7.0E-26 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CIG75_RS13040 1514c9b048a277bb30b7a3a26b0e0cb1 319 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 267 290 7.0E-26 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CIG75_RS13040 1514c9b048a277bb30b7a3a26b0e0cb1 319 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 257 266 7.0E-26 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CIG75_RS13040 1514c9b048a277bb30b7a3a26b0e0cb1 319 Gene3D G3DSA:3.40.50.1370 144 311 1.3E-50 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CIG75_RS13040 1514c9b048a277bb30b7a3a26b0e0cb1 319 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 46 53 - T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CIG75_RS16305 6678177ead9b8629d537320fe3c95653 113 Gene3D G3DSA:3.30.428.10 1 109 3.1E-32 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 CIG75_RS16305 6678177ead9b8629d537320fe3c95653 113 PRINTS PR00332 Histidine triad family signature 5 21 6.3E-21 T 28-03-2018 IPR001310 Histidine triad (HIT) protein CIG75_RS16305 6678177ead9b8629d537320fe3c95653 113 PRINTS PR00332 Histidine triad family signature 94 104 6.3E-21 T 28-03-2018 IPR001310 Histidine triad (HIT) protein CIG75_RS16305 6678177ead9b8629d537320fe3c95653 113 PRINTS PR00332 Histidine triad family signature 26 44 6.3E-21 T 28-03-2018 IPR001310 Histidine triad (HIT) protein CIG75_RS16305 6678177ead9b8629d537320fe3c95653 113 SUPERFAMILY SSF54197 1 111 1.52E-37 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 CIG75_RS16305 6678177ead9b8629d537320fe3c95653 113 Pfam PF01230 HIT domain 12 108 7.5E-26 T 28-03-2018 IPR001310 Histidine triad (HIT) protein CIG75_RS13535 35adb37898095ca480fc4cdfd25be190 143 TIGRFAM TIGR00242 TIGR00242: division/cell wall cluster transcriptional repressor MraZ 1 143 6.4E-53 T 28-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 CIG75_RS13535 35adb37898095ca480fc4cdfd25be190 143 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 143 56.773 T 28-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 CIG75_RS13535 35adb37898095ca480fc4cdfd25be190 143 Pfam PF02381 MraZ protein, putative antitoxin-like 72 140 3.2E-20 T 28-03-2018 IPR020603 MraZ domain CIG75_RS13535 35adb37898095ca480fc4cdfd25be190 143 Pfam PF02381 MraZ protein, putative antitoxin-like 1 70 6.8E-25 T 28-03-2018 IPR020603 MraZ domain CIG75_RS13535 35adb37898095ca480fc4cdfd25be190 143 Gene3D G3DSA:2.10.260.10 74 125 2.0E-4 T 28-03-2018 CIG75_RS13535 35adb37898095ca480fc4cdfd25be190 143 Gene3D G3DSA:2.10.260.10 1 57 3.5E-7 T 28-03-2018 CIG75_RS13535 35adb37898095ca480fc4cdfd25be190 143 SUPERFAMILY SSF89447 1 136 2.49E-51 T 28-03-2018 CIG75_RS13535 35adb37898095ca480fc4cdfd25be190 143 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 1 138 1.0E-47 T 28-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 CIG75_RS14810 6496b7044c57d2bb86952016fd4157ad 608 Gene3D G3DSA:3.30.420.40 1 170 9.7E-69 T 28-03-2018 CIG75_RS14810 6496b7044c57d2bb86952016fd4157ad 608 SUPERFAMILY SSF53067 159 351 2.01E-64 T 28-03-2018 CIG75_RS14810 6496b7044c57d2bb86952016fd4157ad 608 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 603 36.779 T 28-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 CIG75_RS14810 6496b7044c57d2bb86952016fd4157ad 608 SUPERFAMILY SSF53067 1 157 1.81E-58 T 28-03-2018 CIG75_RS14810 6496b7044c57d2bb86952016fd4157ad 608 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CIG75_RS14810 6496b7044c57d2bb86952016fd4157ad 608 SUPERFAMILY SSF100920 353 509 5.1E-61 T 28-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 CIG75_RS14810 6496b7044c57d2bb86952016fd4157ad 608 Pfam PF00012 Hsp70 protein 4 572 7.1E-244 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CIG75_RS14810 6496b7044c57d2bb86952016fd4157ad 608 SUPERFAMILY SSF100934 476 575 3.92E-15 T 28-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain CIG75_RS14810 6496b7044c57d2bb86952016fd4157ad 608 Gene3D G3DSA:2.60.34.10 359 500 3.6E-65 T 28-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 CIG75_RS14810 6496b7044c57d2bb86952016fd4157ad 608 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 165 178 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CIG75_RS14810 6496b7044c57d2bb86952016fd4157ad 608 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 572 2.5E-283 T 28-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 CIG75_RS14810 6496b7044c57d2bb86952016fd4157ad 608 Gene3D G3DSA:1.20.1270.10 501 587 3.7E-23 T 28-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain CIG75_RS14810 6496b7044c57d2bb86952016fd4157ad 608 Gene3D G3DSA:3.30.420.40 171 335 7.2E-47 T 28-03-2018 CIG75_RS14810 6496b7044c57d2bb86952016fd4157ad 608 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 306 320 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CIG75_RS14810 6496b7044c57d2bb86952016fd4157ad 608 PRINTS PR00301 70kDa heat shock protein signature 334 354 2.4E-78 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CIG75_RS14810 6496b7044c57d2bb86952016fd4157ad 608 PRINTS PR00301 70kDa heat shock protein signature 31 43 2.4E-78 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CIG75_RS14810 6496b7044c57d2bb86952016fd4157ad 608 PRINTS PR00301 70kDa heat shock protein signature 357 376 2.4E-78 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CIG75_RS14810 6496b7044c57d2bb86952016fd4157ad 608 PRINTS PR00301 70kDa heat shock protein signature 171 181 2.4E-78 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CIG75_RS14810 6496b7044c57d2bb86952016fd4157ad 608 PRINTS PR00301 70kDa heat shock protein signature 3 16 2.4E-78 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CIG75_RS14810 6496b7044c57d2bb86952016fd4157ad 608 PRINTS PR00301 70kDa heat shock protein signature 112 132 2.4E-78 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CIG75_RS14810 6496b7044c57d2bb86952016fd4157ad 608 PRINTS PR00301 70kDa heat shock protein signature 53 61 2.4E-78 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CIG75_RS14810 6496b7044c57d2bb86952016fd4157ad 608 PRINTS PR00301 70kDa heat shock protein signature 303 319 2.4E-78 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CIG75_RS14810 6496b7044c57d2bb86952016fd4157ad 608 PRINTS PR00301 70kDa heat shock protein signature 438 454 2.4E-78 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CIG75_RS16410 938373cb6ed145db014b8bab2a6b5116 315 Pfam PF02401 LytB protein 4 284 6.5E-83 T 28-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 CIG75_RS16410 938373cb6ed145db014b8bab2a6b5116 315 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 3 286 5.8E-92 T 28-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 CIG75_RS16410 938373cb6ed145db014b8bab2a6b5116 315 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 1 288 32.307 T 28-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 CIG75_RS06755 5c5a3fd6b8efce0e8a53b6398006d03f 427 Gene3D G3DSA:3.40.1080.10 185 422 3.8E-57 T 28-03-2018 CIG75_RS06755 5c5a3fd6b8efce0e8a53b6398006d03f 427 Pfam PF13336 Acetyl-CoA hydrolase/transferase C-terminal domain 267 419 4.5E-58 T 28-03-2018 IPR026888 Acetyl-CoA hydrolase/transferase C-terminal domain CIG75_RS06755 5c5a3fd6b8efce0e8a53b6398006d03f 427 SUPERFAMILY SSF100950 188 424 2.93E-60 T 28-03-2018 CIG75_RS06755 5c5a3fd6b8efce0e8a53b6398006d03f 427 SUPERFAMILY SSF100950 5 218 5.44E-27 T 28-03-2018 CIG75_RS06755 5c5a3fd6b8efce0e8a53b6398006d03f 427 Gene3D G3DSA:3.40.1080.10 6 179 3.4E-26 T 28-03-2018 CIG75_RS06755 5c5a3fd6b8efce0e8a53b6398006d03f 427 Pfam PF02550 Acetyl-CoA hydrolase/transferase N-terminal domain 75 180 4.2E-9 T 28-03-2018 IPR003702 Acetyl-CoA hydrolase/transferase GO:0003824|GO:0006084 CIG75_RS09535 a4286f0d5ce4b90a5d6b6e45e041d884 153 Gene3D G3DSA:2.60.120.10 3 139 1.8E-13 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CIG75_RS09535 a4286f0d5ce4b90a5d6b6e45e041d884 153 Pfam PF07883 Cupin domain 60 124 2.4E-9 T 28-03-2018 IPR013096 Cupin 2, conserved barrel CIG75_RS09535 a4286f0d5ce4b90a5d6b6e45e041d884 153 SUPERFAMILY SSF51182 46 147 1.49E-15 T 28-03-2018 IPR011051 RmlC-like cupin domain CIG75_RS15085 079eac0ec08a68bd12ea9ac4fabf7eb7 287 Gene3D G3DSA:3.40.50.970 6 72 1.9E-16 T 28-03-2018 CIG75_RS15085 079eac0ec08a68bd12ea9ac4fabf7eb7 287 Gene3D G3DSA:3.40.50.970 73 286 2.1E-47 T 28-03-2018 CIG75_RS15085 079eac0ec08a68bd12ea9ac4fabf7eb7 287 SUPERFAMILY SSF52518 11 265 4.15E-77 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CIG75_RS15085 079eac0ec08a68bd12ea9ac4fabf7eb7 287 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 47 194 3.6E-31 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CIG75_RS15085 079eac0ec08a68bd12ea9ac4fabf7eb7 287 TIGRFAM TIGR02177 PorB_KorB: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family 13 266 2.7E-99 T 28-03-2018 IPR011896 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate CIG75_RS15085 079eac0ec08a68bd12ea9ac4fabf7eb7 287 Pfam PF12367 Pyruvate ferredoxin oxidoreductase beta subunit C terminal 198 262 3.7E-19 T 28-03-2018 IPR032686 Pyruvate ferredoxin oxidoreductase beta subunit, C-terminal CIG75_RS18480 3aa81f02cd7fc5b29a719e24938b806a 374 Gene3D G3DSA:3.40.640.10 1 234 7.4E-49 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CIG75_RS18480 3aa81f02cd7fc5b29a719e24938b806a 374 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 9 362 1.3E-130 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CIG75_RS18480 3aa81f02cd7fc5b29a719e24938b806a 374 PIRSF PIRSF000390 1 369 1.3E-133 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CIG75_RS18480 3aa81f02cd7fc5b29a719e24938b806a 374 Gene3D G3DSA:3.90.1150.10 235 374 2.2E-43 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CIG75_RS18480 3aa81f02cd7fc5b29a719e24938b806a 374 SUPERFAMILY SSF53383 2 365 1.77E-121 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CIG75_RS20225 64a79d0ab5146a095394186662567c5c 99 ProDom PD067726 YABP B.SUBTILIS PRECURSOR UNCHARACTERIZED BH0074 SIGNAL CPE2477 PROTEIN 13 99 4.0E-23 T 28-03-2018 IPR012504 Sporulation protein YabP CIG75_RS20225 64a79d0ab5146a095394186662567c5c 99 TIGRFAM TIGR02892 spore_yabP: sporulation protein YabP 14 99 2.2E-28 T 28-03-2018 IPR012504 Sporulation protein YabP CIG75_RS20225 64a79d0ab5146a095394186662567c5c 99 PIRSF PIRSF011576 2 99 4.9E-33 T 28-03-2018 IPR012504 Sporulation protein YabP CIG75_RS20225 64a79d0ab5146a095394186662567c5c 99 Pfam PF07873 YabP family 14 79 5.5E-18 T 28-03-2018 IPR022476 Sporulation protein YabP/YqfC CIG75_RS13575 19e586f58fe7b9496a3fe0f3b668a35c 277 SUPERFAMILY SSF52096 22 276 4.98E-89 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CIG75_RS13575 19e586f58fe7b9496a3fe0f3b668a35c 277 Gene3D G3DSA:1.10.12.10 226 277 5.0E-18 T 28-03-2018 IPR014748 Crontonase, C-terminal CIG75_RS13575 19e586f58fe7b9496a3fe0f3b668a35c 277 Gene3D G3DSA:3.90.226.10 8 225 1.1E-73 T 28-03-2018 CIG75_RS13575 19e586f58fe7b9496a3fe0f3b668a35c 277 Pfam PF00378 Enoyl-CoA hydratase/isomerase 26 276 3.5E-70 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CIG75_RS01340 353f6655c0eb38021774a82a6b226855 204 SUPERFAMILY SSF52833 4 198 2.06E-42 T 28-03-2018 IPR012336 Thioredoxin-like fold CIG75_RS01340 353f6655c0eb38021774a82a6b226855 204 Gene3D G3DSA:3.40.30.10 1 204 1.2E-47 T 28-03-2018 CIG75_RS01340 353f6655c0eb38021774a82a6b226855 204 Pfam PF01323 DSBA-like thioredoxin domain 5 194 2.6E-34 T 28-03-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 CIG75_RS06445 a454c0d8ee198d2a6cfe8041b24f0aab 209 Gene3D G3DSA:1.20.5.170 15 82 1.3E-4 T 28-03-2018 CIG75_RS06445 a454c0d8ee198d2a6cfe8041b24f0aab 209 Gene3D G3DSA:1.20.5.170 83 126 4.7E-6 T 28-03-2018 CIG75_RS06445 a454c0d8ee198d2a6cfe8041b24f0aab 209 SUPERFAMILY SSF58113 35 181 5.1E-13 T 28-03-2018 CIG75_RS06445 a454c0d8ee198d2a6cfe8041b24f0aab 209 Gene3D G3DSA:1.20.120.20 127 203 2.0E-7 T 28-03-2018 CIG75_RS04200 03b9b74dd3b100a4c48d4db4cf9761bc 403 SUPERFAMILY SSF52540 143 361 3.38E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS04200 03b9b74dd3b100a4c48d4db4cf9761bc 403 SMART SM00490 254 335 2.7E-21 T 28-03-2018 IPR001650 Helicase, C-terminal CIG75_RS04200 03b9b74dd3b100a4c48d4db4cf9761bc 403 Gene3D G3DSA:3.40.50.300 9 214 1.5E-47 T 28-03-2018 CIG75_RS04200 03b9b74dd3b100a4c48d4db4cf9761bc 403 SUPERFAMILY SSF52540 3 205 1.3E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS04200 03b9b74dd3b100a4c48d4db4cf9761bc 403 Gene3D G3DSA:3.40.50.300 215 379 2.9E-32 T 28-03-2018 CIG75_RS04200 03b9b74dd3b100a4c48d4db4cf9761bc 403 Pfam PF00270 DEAD/DEAH box helicase 28 192 5.3E-41 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CIG75_RS04200 03b9b74dd3b100a4c48d4db4cf9761bc 403 SMART SM00487 22 218 1.1E-44 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CIG75_RS04200 03b9b74dd3b100a4c48d4db4cf9761bc 403 Pfam PF00271 Helicase conserved C-terminal domain 227 334 1.2E-20 T 28-03-2018 IPR001650 Helicase, C-terminal CIG75_RS02420 bcc5780e882d7ca7a5ec03bea67ac6cf 390 SUPERFAMILY SSF53383 25 384 3.99E-105 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CIG75_RS02420 bcc5780e882d7ca7a5ec03bea67ac6cf 390 PIRSF PIRSF000390 17 389 9.3E-101 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CIG75_RS02420 bcc5780e882d7ca7a5ec03bea67ac6cf 390 Gene3D G3DSA:3.90.1150.10 270 387 7.7E-32 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CIG75_RS02420 bcc5780e882d7ca7a5ec03bea67ac6cf 390 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 30 384 1.4E-98 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CIG75_RS02420 bcc5780e882d7ca7a5ec03bea67ac6cf 390 TIGRFAM TIGR04181 NHT_00031: aminotransferase, LLPSF_NHT_00031 family 21 380 5.1E-171 T 28-03-2018 IPR026385 Aminotransferase, LLPSF_NHT_00031 family CIG75_RS02420 bcc5780e882d7ca7a5ec03bea67ac6cf 390 Gene3D G3DSA:3.40.640.10 20 269 1.8E-46 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CIG75_RS08465 4f15482d9ea3dc6ea2763cb916a4436f 142 TIGRFAM TIGR03081 metmalonyl_epim: methylmalonyl-CoA epimerase 7 134 3.3E-45 T 28-03-2018 IPR017515 Methylmalonyl-CoA epimerase KEGG: 00280+5.1.99.1|KEGG: 00630+5.1.99.1|KEGG: 00640+5.1.99.1|KEGG: 00720+5.1.99.1|MetaCyc: PWY-5741|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384|MetaCyc: PWY-7854|Reactome: R-HSA-71032 CIG75_RS08465 4f15482d9ea3dc6ea2763cb916a4436f 142 SUPERFAMILY SSF54593 6 137 9.49E-34 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CIG75_RS08465 4f15482d9ea3dc6ea2763cb916a4436f 142 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 116 1.9E-20 T 28-03-2018 CIG75_RS08465 4f15482d9ea3dc6ea2763cb916a4436f 142 Gene3D G3DSA:3.10.180.10 2 141 1.5E-28 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CIG75_RS14660 90d2f3feb0a5b2797462c4bbc2a6c95a 482 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 55 243 3.0E-33 T 28-03-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 CIG75_RS14660 90d2f3feb0a5b2797462c4bbc2a6c95a 482 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 253 305 2.9E-9 T 28-03-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 CIG75_RS14660 90d2f3feb0a5b2797462c4bbc2a6c95a 482 Gene3D G3DSA:3.30.1490.20 2 194 1.2E-47 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CIG75_RS14660 90d2f3feb0a5b2797462c4bbc2a6c95a 482 Gene3D G3DSA:1.10.189.10 292 339 6.3E-13 T 28-03-2018 CIG75_RS14660 90d2f3feb0a5b2797462c4bbc2a6c95a 482 Pfam PF00391 PEP-utilising enzyme, mobile domain 371 451 9.9E-22 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CIG75_RS14660 90d2f3feb0a5b2797462c4bbc2a6c95a 482 SUPERFAMILY SSF56059 3 328 3.41E-108 T 28-03-2018 CIG75_RS14660 90d2f3feb0a5b2797462c4bbc2a6c95a 482 SUPERFAMILY SSF52009 339 460 1.31E-30 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CIG75_RS14660 90d2f3feb0a5b2797462c4bbc2a6c95a 482 Gene3D G3DSA:3.30.470.20 195 291 7.0E-20 T 28-03-2018 CIG75_RS14660 90d2f3feb0a5b2797462c4bbc2a6c95a 482 Gene3D G3DSA:3.50.30.10 340 481 5.6E-30 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CIG75_RS14030 33047072a5645430da22d1f7d41c0f7c 151 SUPERFAMILY SSF55729 30 142 2.62E-15 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CIG75_RS14030 33047072a5645430da22d1f7d41c0f7c 151 PIRSF PIRSF037732 1 151 3.6E-64 T 28-03-2018 IPR017274 Putative N-acetyltransferase YlbP CIG75_RS14030 33047072a5645430da22d1f7d41c0f7c 151 Gene3D G3DSA:3.40.630.30 1 151 4.2E-24 T 28-03-2018 CIG75_RS14030 33047072a5645430da22d1f7d41c0f7c 151 Pfam PF13508 Acetyltransferase (GNAT) domain 47 131 7.5E-8 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CIG75_RS08010 f1685cb51c4d0375aa298840fa7393cd 220 SMART SM00382 30 217 7.4E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS08010 f1685cb51c4d0375aa298840fa7393cd 220 SUPERFAMILY SSF52540 1 220 1.52E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS08010 f1685cb51c4d0375aa298840fa7393cd 220 Pfam PF00005 ABC transporter 21 169 2.8E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS08010 f1685cb51c4d0375aa298840fa7393cd 220 Gene3D G3DSA:3.40.50.300 1 220 2.0E-62 T 28-03-2018 CIG75_RS08010 f1685cb51c4d0375aa298840fa7393cd 220 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS01820 a37ae2cc331e253f9d03ddbb0b19ec76 252 TIGRFAM TIGR02837 spore_II_R: stage II sporulation protein R 59 201 7.0E-54 T 28-03-2018 IPR014202 Sporulation stage II, protein R CIG75_RS01820 a37ae2cc331e253f9d03ddbb0b19ec76 252 Pfam PF09551 Stage II sporulation protein R (spore_II_R) 72 196 7.1E-46 T 28-03-2018 IPR014202 Sporulation stage II, protein R CIG75_RS01600 a3e0e8b94cd5f07954b19a07b97b7f2c 677 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 354 365 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CIG75_RS01600 a3e0e8b94cd5f07954b19a07b97b7f2c 677 Pfam PF13183 4Fe-4S dicluster domain 271 367 1.3E-11 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CIG75_RS01600 a3e0e8b94cd5f07954b19a07b97b7f2c 677 Gene3D G3DSA:1.20.950.20 1 231 2.4E-38 T 28-03-2018 CIG75_RS01600 a3e0e8b94cd5f07954b19a07b97b7f2c 677 SUPERFAMILY SSF103501 3 232 1.83E-13 T 28-03-2018 IPR023234 NarG-like domain CIG75_RS01600 a3e0e8b94cd5f07954b19a07b97b7f2c 677 SUPERFAMILY SSF46548 337 382 1.74E-16 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CIG75_RS01600 a3e0e8b94cd5f07954b19a07b97b7f2c 677 SUPERFAMILY SSF46548 250 304 1.74E-16 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CIG75_RS01600 a3e0e8b94cd5f07954b19a07b97b7f2c 677 Gene3D G3DSA:1.10.1060.10 240 387 1.3E-26 T 28-03-2018 CIG75_RS01600 a3e0e8b94cd5f07954b19a07b97b7f2c 677 Pfam PF02754 Cysteine-rich domain 560 646 1.3E-17 T 28-03-2018 IPR004017 Cysteine-rich domain CIG75_RS01600 a3e0e8b94cd5f07954b19a07b97b7f2c 677 Pfam PF02754 Cysteine-rich domain 443 517 9.1E-7 T 28-03-2018 IPR004017 Cysteine-rich domain CIG75_RS05345 4a6f6ada5e0e64bbbdb98763805ff656 248 Gene3D G3DSA:3.30.450.40 76 248 1.3E-41 T 28-03-2018 IPR029016 GAF domain-like CIG75_RS05345 4a6f6ada5e0e64bbbdb98763805ff656 248 SMART SM00346 10 100 6.9E-24 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CIG75_RS05345 4a6f6ada5e0e64bbbdb98763805ff656 248 Pfam PF09339 IclR helix-turn-helix domain 12 63 8.4E-19 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CIG75_RS05345 4a6f6ada5e0e64bbbdb98763805ff656 248 SUPERFAMILY SSF55781 68 246 9.16E-42 T 28-03-2018 IPR029016 GAF domain-like CIG75_RS05345 4a6f6ada5e0e64bbbdb98763805ff656 248 SUPERFAMILY SSF46785 10 78 1.25E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS05345 4a6f6ada5e0e64bbbdb98763805ff656 248 Pfam PF01614 Bacterial transcriptional regulator 130 246 2.3E-25 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal CIG75_RS05345 4a6f6ada5e0e64bbbdb98763805ff656 248 Gene3D G3DSA:1.10.10.10 1 71 2.4E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS19575 3ac9f9c7ae9bde05ad3aa9c85204285e 144 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 5 141 1.1E-62 T 28-03-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS19575 3ac9f9c7ae9bde05ad3aa9c85204285e 144 Pfam PF00572 Ribosomal protein L13 15 138 5.5E-57 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CIG75_RS19575 3ac9f9c7ae9bde05ad3aa9c85204285e 144 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 16 140 28.246 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CIG75_RS19575 3ac9f9c7ae9bde05ad3aa9c85204285e 144 Gene3D G3DSA:3.90.1180.10 1 144 1.7E-62 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CIG75_RS19575 3ac9f9c7ae9bde05ad3aa9c85204285e 144 ProSitePatterns PS00783 Ribosomal protein L13 signature. 106 128 - T 28-03-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 CIG75_RS19575 3ac9f9c7ae9bde05ad3aa9c85204285e 144 PIRSF PIRSF002181 1 142 2.2E-50 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CIG75_RS19575 3ac9f9c7ae9bde05ad3aa9c85204285e 144 SUPERFAMILY SSF52161 5 142 5.36E-60 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CIG75_RS07710 fa4b199eb96069497747d95d5ca338b0 104 SUPERFAMILY SSF52833 3 104 4.59E-36 T 28-03-2018 IPR012336 Thioredoxin-like fold CIG75_RS07710 fa4b199eb96069497747d95d5ca338b0 104 Gene3D G3DSA:3.40.30.10 1 104 6.7E-34 T 28-03-2018 CIG75_RS07710 fa4b199eb96069497747d95d5ca338b0 104 TIGRFAM TIGR01068 thioredoxin: thioredoxin 7 102 1.8E-35 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 CIG75_RS07710 fa4b199eb96069497747d95d5ca338b0 104 Pfam PF00085 Thioredoxin 4 101 1.1E-30 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 CIG75_RS07710 fa4b199eb96069497747d95d5ca338b0 104 PIRSF PIRSF000077 1 104 7.8E-37 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 CIG75_RS07710 fa4b199eb96069497747d95d5ca338b0 104 PRINTS PR00421 Thioredoxin family signature 20 28 4.2E-8 T 28-03-2018 CIG75_RS07710 fa4b199eb96069497747d95d5ca338b0 104 PRINTS PR00421 Thioredoxin family signature 28 37 4.2E-8 T 28-03-2018 CIG75_RS07710 fa4b199eb96069497747d95d5ca338b0 104 PRINTS PR00421 Thioredoxin family signature 68 79 4.2E-8 T 28-03-2018 CIG75_RS07710 fa4b199eb96069497747d95d5ca338b0 104 ProSitePatterns PS00194 Thioredoxin family active site. 21 39 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 CIG75_RS03010 5bdad3b3fb2ebc41154d760037157bd5 214 Pfam PF02223 Thymidylate kinase 11 147 2.6E-14 T 28-03-2018 CIG75_RS03010 5bdad3b3fb2ebc41154d760037157bd5 214 SUPERFAMILY SSF52540 1 210 6.47E-24 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS03010 5bdad3b3fb2ebc41154d760037157bd5 214 Hamap MF_00165 Thymidylate kinase [tmk]. 7 211 15.159 T 28-03-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CIG75_RS03010 5bdad3b3fb2ebc41154d760037157bd5 214 Gene3D G3DSA:3.40.50.300 1 199 2.8E-26 T 28-03-2018 CIG75_RS17775 1aaf6e5812d116b8647aedf9ec1b0f3a 391 Gene3D G3DSA:3.40.630.10 268 391 2.3E-22 T 28-03-2018 CIG75_RS17775 1aaf6e5812d116b8647aedf9ec1b0f3a 391 Pfam PF07687 Peptidase dimerisation domain 186 281 1.2E-12 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CIG75_RS17775 1aaf6e5812d116b8647aedf9ec1b0f3a 391 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 16 377 1.5E-126 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CIG75_RS17775 1aaf6e5812d116b8647aedf9ec1b0f3a 391 Gene3D G3DSA:3.40.630.10 1 267 1.0E-70 T 28-03-2018 CIG75_RS17775 1aaf6e5812d116b8647aedf9ec1b0f3a 391 SUPERFAMILY SSF53187 299 389 2.17E-91 T 28-03-2018 CIG75_RS17775 1aaf6e5812d116b8647aedf9ec1b0f3a 391 SUPERFAMILY SSF53187 7 198 2.17E-91 T 28-03-2018 CIG75_RS17775 1aaf6e5812d116b8647aedf9ec1b0f3a 391 PIRSF PIRSF005962 1 391 5.5E-137 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CIG75_RS17775 1aaf6e5812d116b8647aedf9ec1b0f3a 391 Pfam PF01546 Peptidase family M20/M25/M40 74 382 5.4E-35 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CIG75_RS17775 1aaf6e5812d116b8647aedf9ec1b0f3a 391 SUPERFAMILY SSF55031 184 297 4.3E-33 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CIG75_RS02760 e7ebaf8bba8dbc91cb50067baec98ce5 232 Gene3D G3DSA:2.60.120.10 7 150 8.9E-16 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CIG75_RS02760 e7ebaf8bba8dbc91cb50067baec98ce5 232 Pfam PF00027 Cyclic nucleotide-binding domain 35 107 1.1E-12 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CIG75_RS02760 e7ebaf8bba8dbc91cb50067baec98ce5 232 ProSitePatterns PS00888 Cyclic nucleotide-binding domain signature 1. 42 58 - T 28-03-2018 IPR018488 Cyclic nucleotide-binding, conserved site CIG75_RS02760 e7ebaf8bba8dbc91cb50067baec98ce5 232 SUPERFAMILY SSF46785 151 227 1.85E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS02760 e7ebaf8bba8dbc91cb50067baec98ce5 232 Gene3D G3DSA:1.10.10.10 151 232 1.8E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS02760 e7ebaf8bba8dbc91cb50067baec98ce5 232 Pfam PF13545 Crp-like helix-turn-helix domain 154 225 1.6E-11 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CIG75_RS02760 e7ebaf8bba8dbc91cb50067baec98ce5 232 SUPERFAMILY SSF51206 25 141 1.96E-23 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like CIG75_RS17865 04488cf5bd0c917cfa7cf6d95d94e03e 712 SUPERFAMILY SSF52540 219 357 9.25E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS17865 04488cf5bd0c917cfa7cf6d95d94e03e 712 SUPERFAMILY SSF52540 29 190 9.25E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS17865 04488cf5bd0c917cfa7cf6d95d94e03e 712 Pfam PF00271 Helicase conserved C-terminal domain 245 350 5.1E-13 T 28-03-2018 IPR001650 Helicase, C-terminal CIG75_RS17865 04488cf5bd0c917cfa7cf6d95d94e03e 712 SMART SM00487 13 218 9.2E-35 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CIG75_RS17865 04488cf5bd0c917cfa7cf6d95d94e03e 712 Pfam PF00270 DEAD/DEAH box helicase 19 188 5.7E-30 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CIG75_RS17865 04488cf5bd0c917cfa7cf6d95d94e03e 712 Pfam PF09369 Domain of unknown function (DUF1998) 613 690 6.3E-20 T 28-03-2018 IPR018973 DEAD/DEAH-box helicase, putative CIG75_RS17865 04488cf5bd0c917cfa7cf6d95d94e03e 712 SMART SM00490 264 351 5.2E-13 T 28-03-2018 IPR001650 Helicase, C-terminal CIG75_RS17865 04488cf5bd0c917cfa7cf6d95d94e03e 712 Gene3D G3DSA:3.40.50.300 232 375 4.1E-20 T 28-03-2018 CIG75_RS17865 04488cf5bd0c917cfa7cf6d95d94e03e 712 Gene3D G3DSA:3.40.50.300 7 201 3.0E-36 T 28-03-2018 CIG75_RS07565 b5a0d2700194d1aa37966572260bde86 151 Gene3D G3DSA:1.10.10.10 9 93 1.1E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS07565 b5a0d2700194d1aa37966572260bde86 151 SUPERFAMILY SSF46785 10 137 1.11E-38 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS07565 b5a0d2700194d1aa37966572260bde86 151 Pfam PF01475 Ferric uptake regulator family 16 133 3.7E-36 T 28-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CIG75_RS15500 c859552aa4407fed47e12e5c83b1f67f 261 PRINTS PR00111 Alpha/beta hydrolase fold signature 37 52 3.6E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CIG75_RS15500 c859552aa4407fed47e12e5c83b1f67f 261 PRINTS PR00111 Alpha/beta hydrolase fold signature 82 95 3.6E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CIG75_RS15500 c859552aa4407fed47e12e5c83b1f67f 261 PRINTS PR00111 Alpha/beta hydrolase fold signature 96 109 3.6E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CIG75_RS15500 c859552aa4407fed47e12e5c83b1f67f 261 SUPERFAMILY SSF53474 3 250 7.8E-53 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS15500 c859552aa4407fed47e12e5c83b1f67f 261 Pfam PF12146 Serine aminopeptidase, S33 14 234 9.6E-17 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 CIG75_RS15500 c859552aa4407fed47e12e5c83b1f67f 261 Gene3D G3DSA:3.40.50.1820 1 259 5.3E-39 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS05160 1a88887ef25658fe7279ad7a0bba77dd 269 Pfam PF08282 haloacid dehalogenase-like hydrolase 9 265 2.0E-64 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS05160 1a88887ef25658fe7279ad7a0bba77dd 269 SUPERFAMILY SSF56784 3 269 3.78E-69 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS05160 1a88887ef25658fe7279ad7a0bba77dd 269 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 8 265 1.8E-58 T 28-03-2018 IPR000150 Cof family GO:0016787 CIG75_RS05160 1a88887ef25658fe7279ad7a0bba77dd 269 ProSitePatterns PS01228 Hypothetical cof family signature 1. 8 19 - T 28-03-2018 CIG75_RS05160 1a88887ef25658fe7279ad7a0bba77dd 269 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 8 238 5.8E-25 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CIG75_RS05160 1a88887ef25658fe7279ad7a0bba77dd 269 Gene3D G3DSA:3.40.50.1000 1 269 3.6E-42 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS07885 c33c365e19d2a76b0b3085598951a189 472 PIRSF PIRSF000445 1 436 3.3E-159 T 28-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CIG75_RS07885 c33c365e19d2a76b0b3085598951a189 472 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 6 156 1.6E-44 T 28-03-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CIG75_RS07885 c33c365e19d2a76b0b3085598951a189 472 SUPERFAMILY SSF69075 317 420 7.45E-18 T 28-03-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CIG75_RS07885 c33c365e19d2a76b0b3085598951a189 472 Gene3D G3DSA:3.40.50.720 161 313 1.2E-30 T 28-03-2018 CIG75_RS07885 c33c365e19d2a76b0b3085598951a189 472 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 2 417 30.153 T 28-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CIG75_RS07885 c33c365e19d2a76b0b3085598951a189 472 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 99 122 - T 28-03-2018 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CIG75_RS07885 c33c365e19d2a76b0b3085598951a189 472 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 320 419 1.8E-22 T 28-03-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CIG75_RS07885 c33c365e19d2a76b0b3085598951a189 472 Gene3D G3DSA:1.10.1200.70 332 420 6.3E-22 T 28-03-2018 CIG75_RS07885 c33c365e19d2a76b0b3085598951a189 472 SUPERFAMILY SSF69742 1 158 7.59E-46 T 28-03-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CIG75_RS07885 c33c365e19d2a76b0b3085598951a189 472 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 171 306 6.0E-49 T 28-03-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase CIG75_RS07885 c33c365e19d2a76b0b3085598951a189 472 SUPERFAMILY SSF51735 162 315 1.18E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS07885 c33c365e19d2a76b0b3085598951a189 472 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 3 420 2.2E-147 T 28-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CIG75_RS12220 b283527465dc19e3c603a3646f3c76f7 192 Gene3D G3DSA:2.10.109.10 44 192 7.0E-50 T 28-03-2018 CIG75_RS12220 b283527465dc19e3c603a3646f3c76f7 192 ProSitePatterns PS00760 Signal peptidases I lysine active site. 102 114 - T 28-03-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 CIG75_RS12220 b283527465dc19e3c603a3646f3c76f7 192 ProSitePatterns PS00501 Signal peptidases I serine active site. 57 64 - T 28-03-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 CIG75_RS12220 b283527465dc19e3c603a3646f3c76f7 192 ProSitePatterns PS00761 Signal peptidases I signature 3. 149 162 - T 28-03-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 CIG75_RS12220 b283527465dc19e3c603a3646f3c76f7 192 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 100 112 5.3E-21 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CIG75_RS12220 b283527465dc19e3c603a3646f3c76f7 192 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 144 163 5.3E-21 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CIG75_RS12220 b283527465dc19e3c603a3646f3c76f7 192 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 48 64 5.3E-21 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CIG75_RS12220 b283527465dc19e3c603a3646f3c76f7 192 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 33 187 1.4E-52 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CIG75_RS12220 b283527465dc19e3c603a3646f3c76f7 192 SUPERFAMILY SSF51306 46 192 1.15E-51 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CIG75_RS12220 b283527465dc19e3c603a3646f3c76f7 192 Pfam PF00717 Peptidase S24-like 55 117 1.7E-16 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CIG75_RS05255 629b47bf39c6b4974c2d9e1ee51de8ce 477 Gene3D G3DSA:3.90.780.10 291 468 1.5E-27 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CIG75_RS05255 629b47bf39c6b4974c2d9e1ee51de8ce 477 Gene3D G3DSA:3.60.21.10 1 290 4.2E-55 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CIG75_RS05255 629b47bf39c6b4974c2d9e1ee51de8ce 477 SUPERFAMILY SSF56300 2 271 1.01E-62 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CIG75_RS05255 629b47bf39c6b4974c2d9e1ee51de8ce 477 PRINTS PR01607 Apyrase family signature 187 210 8.1E-27 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CIG75_RS05255 629b47bf39c6b4974c2d9e1ee51de8ce 477 PRINTS PR01607 Apyrase family signature 168 185 8.1E-27 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CIG75_RS05255 629b47bf39c6b4974c2d9e1ee51de8ce 477 PRINTS PR01607 Apyrase family signature 329 352 8.1E-27 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CIG75_RS05255 629b47bf39c6b4974c2d9e1ee51de8ce 477 PRINTS PR01607 Apyrase family signature 413 432 8.1E-27 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CIG75_RS05255 629b47bf39c6b4974c2d9e1ee51de8ce 477 PRINTS PR01607 Apyrase family signature 1 17 8.1E-27 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CIG75_RS05255 629b47bf39c6b4974c2d9e1ee51de8ce 477 PRINTS PR01607 Apyrase family signature 215 235 8.1E-27 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CIG75_RS05255 629b47bf39c6b4974c2d9e1ee51de8ce 477 Pfam PF02872 5'-nucleotidase, C-terminal domain 284 429 7.1E-21 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CIG75_RS05255 629b47bf39c6b4974c2d9e1ee51de8ce 477 Pfam PF00149 Calcineurin-like phosphoesterase 4 204 5.1E-9 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CIG75_RS05255 629b47bf39c6b4974c2d9e1ee51de8ce 477 SUPERFAMILY SSF55816 276 431 1.26E-27 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CIG75_RS04160 5230e3245fc0cf9a0e633b768ffb314f 178 Gene3D G3DSA:3.40.50.1240 23 178 2.1E-15 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CIG75_RS04160 5230e3245fc0cf9a0e633b768ffb314f 178 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 42 177 1.8E-12 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CIG75_RS04160 5230e3245fc0cf9a0e633b768ffb314f 178 SUPERFAMILY SSF53254 46 177 2.78E-16 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CIG75_RS01140 970545eaf12edbbc38a0026075dbd9ab 286 Pfam PF13508 Acetyltransferase (GNAT) domain 194 276 3.1E-11 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CIG75_RS01140 970545eaf12edbbc38a0026075dbd9ab 286 Pfam PF00583 Acetyltransferase (GNAT) family 48 113 6.7E-6 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CIG75_RS01140 970545eaf12edbbc38a0026075dbd9ab 286 Gene3D G3DSA:3.40.630.30 142 286 2.8E-24 T 28-03-2018 CIG75_RS01140 970545eaf12edbbc38a0026075dbd9ab 286 SUPERFAMILY SSF55729 114 282 1.23E-26 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CIG75_RS01140 970545eaf12edbbc38a0026075dbd9ab 286 Gene3D G3DSA:3.40.630.30 9 141 1.7E-12 T 28-03-2018 CIG75_RS01140 970545eaf12edbbc38a0026075dbd9ab 286 SUPERFAMILY SSF55729 20 136 9.66E-13 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CIG75_RS03445 c7f1057637aa3fc2c516b6800d84c816 350 Gene3D G3DSA:3.90.1150.10 250 345 1.5E-28 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CIG75_RS03445 c7f1057637aa3fc2c516b6800d84c816 350 Gene3D G3DSA:3.40.640.10 1 249 3.0E-46 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CIG75_RS03445 c7f1057637aa3fc2c516b6800d84c816 350 PIRSF PIRSF017617 1 349 9.2E-128 T 28-03-2018 IPR023603 Threonine aldolase CIG75_RS03445 c7f1057637aa3fc2c516b6800d84c816 350 Pfam PF01212 Beta-eliminating lyase 4 288 4.0E-85 T 28-03-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 CIG75_RS03445 c7f1057637aa3fc2c516b6800d84c816 350 SUPERFAMILY SSF53383 1 343 1.61E-112 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CIG75_RS12305 78e169ba8e372f5f4e91ef66ba1ef966 141 Pfam PF11068 YlqD protein 4 135 4.4E-33 T 28-03-2018 IPR021297 YlqD protein CIG75_RS12650 2283a120bdd5298f7171ada4215bdbcc 784 SUPERFAMILY SSF48452 372 438 2.13E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS12650 2283a120bdd5298f7171ada4215bdbcc 784 SUPERFAMILY SSF48452 627 675 2.13E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS12650 2283a120bdd5298f7171ada4215bdbcc 784 SUPERFAMILY SSF52467 6 228 4.63E-18 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CIG75_RS12650 2283a120bdd5298f7171ada4215bdbcc 784 Gene3D G3DSA:3.40.50.1220 3 262 9.1E-14 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CIG75_RS12650 2283a120bdd5298f7171ada4215bdbcc 784 Gene3D G3DSA:1.25.40.10 620 771 0.0075 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS12650 2283a120bdd5298f7171ada4215bdbcc 784 Gene3D G3DSA:1.25.40.10 347 574 5.1E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS14980 3a8f894969f03ecfd610dc2a2b0bbc06 189 Gene3D G3DSA:3.40.630.30 20 180 3.6E-20 T 28-03-2018 CIG75_RS14980 3a8f894969f03ecfd610dc2a2b0bbc06 189 Pfam PF00583 Acetyltransferase (GNAT) family 85 171 4.7E-11 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CIG75_RS14980 3a8f894969f03ecfd610dc2a2b0bbc06 189 SUPERFAMILY SSF55729 44 177 2.62E-19 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CIG75_RS15285 24ae60c5dafbb622f76f5da59390a3c0 415 Pfam PF13641 Glycosyltransferase like family 2 48 272 3.7E-27 T 28-03-2018 CIG75_RS15285 24ae60c5dafbb622f76f5da59390a3c0 415 Gene3D G3DSA:3.90.550.10 34 305 5.6E-35 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CIG75_RS15285 24ae60c5dafbb622f76f5da59390a3c0 415 SUPERFAMILY SSF53448 47 346 5.91E-42 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CIG75_RS18745 aaff5c6de6050634a658294b6f920275 94 SUPERFAMILY SSF50129 1 93 8.71E-33 T 28-03-2018 IPR011032 GroES-like CIG75_RS18745 aaff5c6de6050634a658294b6f920275 94 PRINTS PR00297 10kDa chaperonin signature 58 70 2.0E-31 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CIG75_RS18745 aaff5c6de6050634a658294b6f920275 94 PRINTS PR00297 10kDa chaperonin signature 24 45 2.0E-31 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CIG75_RS18745 aaff5c6de6050634a658294b6f920275 94 PRINTS PR00297 10kDa chaperonin signature 79 92 2.0E-31 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CIG75_RS18745 aaff5c6de6050634a658294b6f920275 94 PRINTS PR00297 10kDa chaperonin signature 2 17 2.0E-31 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CIG75_RS18745 aaff5c6de6050634a658294b6f920275 94 ProSitePatterns PS00681 Chaperonins cpn10 signature. 2 26 - T 28-03-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 CIG75_RS18745 aaff5c6de6050634a658294b6f920275 94 Pfam PF00166 Chaperonin 10 Kd subunit 2 92 1.4E-32 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CIG75_RS18745 aaff5c6de6050634a658294b6f920275 94 Gene3D G3DSA:2.30.33.40 1 93 9.6E-36 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CIG75_RS18745 aaff5c6de6050634a658294b6f920275 94 SMART SM00883 1 92 3.2E-52 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CIG75_RS18745 aaff5c6de6050634a658294b6f920275 94 Hamap MF_00580 10 kDa chaperonin [groS]. 1 93 25.852 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CIG75_RS15490 3649148b9d52f8c86c14db9fc17ffe20 243 SMART SM00316 27 98 1.1E-5 T 28-03-2018 IPR022967 RNA-binding domain, S1 CIG75_RS15490 3649148b9d52f8c86c14db9fc17ffe20 243 SUPERFAMILY SSF50249 17 97 1.44E-10 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CIG75_RS15490 3649148b9d52f8c86c14db9fc17ffe20 243 Gene3D G3DSA:2.40.50.140 19 104 1.2E-10 T 28-03-2018 CIG75_RS03640 577a7763084779b25ca923ac75781c34 729 SUPERFAMILY SSF52540 30 372 1.64E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS03640 577a7763084779b25ca923ac75781c34 729 SMART SM00487 18 227 5.3E-31 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CIG75_RS03640 577a7763084779b25ca923ac75781c34 729 Pfam PF00271 Helicase conserved C-terminal domain 249 357 2.0E-16 T 28-03-2018 IPR001650 Helicase, C-terminal CIG75_RS03640 577a7763084779b25ca923ac75781c34 729 SMART SM00490 279 359 5.4E-14 T 28-03-2018 IPR001650 Helicase, C-terminal CIG75_RS03640 577a7763084779b25ca923ac75781c34 729 Pfam PF00270 DEAD/DEAH box helicase 23 199 1.0E-30 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CIG75_RS03640 577a7763084779b25ca923ac75781c34 729 Gene3D G3DSA:3.40.50.300 229 388 1.9E-25 T 28-03-2018 CIG75_RS03640 577a7763084779b25ca923ac75781c34 729 Gene3D G3DSA:3.40.50.300 2 228 3.0E-33 T 28-03-2018 CIG75_RS16375 e0919e37cbd0b8ea8580cb4be2c8dbce 388 SUPERFAMILY SSF54593 26 375 4.7E-91 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CIG75_RS16375 e0919e37cbd0b8ea8580cb4be2c8dbce 388 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 202 342 8.0E-19 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CIG75_RS16375 e0919e37cbd0b8ea8580cb4be2c8dbce 388 Gene3D G3DSA:3.10.180.10 188 388 4.3E-70 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CIG75_RS16375 e0919e37cbd0b8ea8580cb4be2c8dbce 388 Gene3D G3DSA:3.10.180.10 24 187 4.9E-30 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CIG75_RS16375 e0919e37cbd0b8ea8580cb4be2c8dbce 388 PIRSF PIRSF009283 21 388 4.7E-140 T 28-03-2018 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 CIG75_RS16375 e0919e37cbd0b8ea8580cb4be2c8dbce 388 Pfam PF14696 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal 34 164 1.0E-9 T 28-03-2018 CIG75_RS16375 e0919e37cbd0b8ea8580cb4be2c8dbce 388 TIGRFAM TIGR01263 4HPPD: 4-hydroxyphenylpyruvate dioxygenase 34 388 4.2E-140 T 28-03-2018 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 CIG75_RS10085 a5038c8423939d2a1d348764c47c37cb 141 SMART SM00422 12 80 3.5E-23 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CIG75_RS10085 a5038c8423939d2a1d348764c47c37cb 141 SUPERFAMILY SSF46955 12 101 1.03E-19 T 28-03-2018 IPR009061 Putative DNA-binding domain CIG75_RS10085 a5038c8423939d2a1d348764c47c37cb 141 Gene3D G3DSA:1.10.1660.10 1 123 7.5E-23 T 28-03-2018 CIG75_RS10085 a5038c8423939d2a1d348764c47c37cb 141 Pfam PF13411 MerR HTH family regulatory protein 13 77 2.0E-19 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CIG75_RS01230 e4bb8e4c44c6babba96fb8c0d84fa45b 228 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 52 145 2.2E-17 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CIG75_RS01230 e4bb8e4c44c6babba96fb8c0d84fa45b 228 SUPERFAMILY SSF50475 37 198 9.62E-20 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CIG75_RS01230 e4bb8e4c44c6babba96fb8c0d84fa45b 228 Gene3D G3DSA:2.30.110.10 43 202 1.6E-29 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CIG75_RS01230 e4bb8e4c44c6babba96fb8c0d84fa45b 228 TIGRFAM TIGR04025 PPOX_FMN_DR2398: pyridoxamine 5'-phosphate oxidase, FMN-binding family 32 228 3.8E-80 T 28-03-2018 IPR024029 Pyridoxamine 5-phosphate oxidase, FMN-dependent CIG75_RS12535 e10e4ff92d0de87bcdadafc251c6118c 88 Hamap MF_01503 UPF0296 protein . 3 88 29.925 T 28-03-2018 IPR007169 Uncharacterised protein family UPF0296 CIG75_RS12535 e10e4ff92d0de87bcdadafc251c6118c 88 Pfam PF04025 Domain of unknown function (DUF370) 5 77 1.1E-37 T 28-03-2018 IPR007169 Uncharacterised protein family UPF0296 CIG75_RS12535 e10e4ff92d0de87bcdadafc251c6118c 88 ProDom PD063023 UPF0296 YLZA BA4010/GBAA4010/BAS3723 BLI01788/BL02292 BT9727_3613 BC3870 TM1690 CBDBA43 SYC0519_C BCE33L3631 5 77 1.0E-34 T 28-03-2018 IPR007169 Uncharacterised protein family UPF0296 CIG75_RS11080 f7e0299fb117a86d367d3a399c1e21ee 606 Pfam PF13519 von Willebrand factor type A domain 90 192 1.1E-11 T 28-03-2018 IPR002035 von Willebrand factor, type A CIG75_RS11080 f7e0299fb117a86d367d3a399c1e21ee 606 SUPERFAMILY SSF53300 91 196 3.78E-8 T 28-03-2018 IPR002035 von Willebrand factor, type A CIG75_RS11080 f7e0299fb117a86d367d3a399c1e21ee 606 Gene3D G3DSA:2.60.120.430 207 331 1.3E-4 T 28-03-2018 CIG75_RS11080 f7e0299fb117a86d367d3a399c1e21ee 606 Gene3D G3DSA:3.40.50.410 87 193 8.5E-7 T 28-03-2018 IPR002035 von Willebrand factor, type A CIG75_RS11080 f7e0299fb117a86d367d3a399c1e21ee 606 TIGRFAM TIGR02226 two_anch: N-terminal double-transmembrane domain 1 82 1.1E-7 T 28-03-2018 IPR011933 Double transmembrane domain CIG75_RS11080 f7e0299fb117a86d367d3a399c1e21ee 606 Pfam PF07584 Aerotolerance regulator N-terminal 1 78 8.7E-20 T 28-03-2018 IPR024163 Aerotolerance regulator, N-terminal CIG75_RS07510 19c8c845632aa7ad9aac25d230faa348 143 Pfam PF03745 Domain of unknown function (DUF309) 12 63 8.2E-18 T 28-03-2018 IPR005500 Protein of unknown function DUF309 CIG75_RS07510 19c8c845632aa7ad9aac25d230faa348 143 Gene3D G3DSA:1.10.3450.10 2 126 3.9E-27 T 28-03-2018 IPR023203 TTHA0068-like domain CIG75_RS07510 19c8c845632aa7ad9aac25d230faa348 143 SUPERFAMILY SSF140663 7 96 2.62E-25 T 28-03-2018 IPR023203 TTHA0068-like domain CIG75_RS01055 b3ff51a58dcba5e9fcfe86af92a69914 94 Hamap MF_00330 Cobalt transport protein CbiN [cbiN]. 1 94 37.618 T 28-03-2018 IPR003705 Cobalt transport protein CbiN GO:0006824|GO:0009236|GO:0015087|GO:0016020 CIG75_RS01055 b3ff51a58dcba5e9fcfe86af92a69914 94 Pfam PF02553 Cobalt transport protein component CbiN 7 71 1.6E-23 T 28-03-2018 IPR003705 Cobalt transport protein CbiN GO:0006824|GO:0009236|GO:0015087|GO:0016020 CIG75_RS16505 c340f36192952197ce88f303b9de3051 70 Pfam PF13751 Transposase DDE domain 8 59 2.6E-10 T 28-03-2018 IPR025668 Transposase DDE domain CIG75_RS20315 7bb370b64a86a3a7a13d97c3490330cb 237 SUPERFAMILY SSF53448 1 223 9.73E-29 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CIG75_RS20315 7bb370b64a86a3a7a13d97c3490330cb 237 Gene3D G3DSA:3.90.550.10 1 50 5.0E-5 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CIG75_RS20315 7bb370b64a86a3a7a13d97c3490330cb 237 Pfam PF12804 MobA-like NTP transferase domain 58 143 2.7E-6 T 28-03-2018 IPR025877 MobA-like NTP transferase CIG75_RS20315 7bb370b64a86a3a7a13d97c3490330cb 237 Gene3D G3DSA:3.90.550.10 51 236 9.5E-9 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CIG75_RS17690 1ed42187c85fc38b9242cb76a0dc9629 575 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 438 559 8.5E-22 T 28-03-2018 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CIG75_RS17690 1ed42187c85fc38b9242cb76a0dc9629 575 SUPERFAMILY SSF51905 318 373 3.89E-36 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS17690 1ed42187c85fc38b9242cb76a0dc9629 575 SUPERFAMILY SSF51905 23 250 3.89E-36 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS17690 1ed42187c85fc38b9242cb76a0dc9629 575 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 36 46 4.5E-31 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CIG75_RS17690 1ed42187c85fc38b9242cb76a0dc9629 575 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 397 409 4.5E-31 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CIG75_RS17690 1ed42187c85fc38b9242cb76a0dc9629 575 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 97 109 4.5E-31 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CIG75_RS17690 1ed42187c85fc38b9242cb76a0dc9629 575 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 23 35 4.5E-31 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CIG75_RS17690 1ed42187c85fc38b9242cb76a0dc9629 575 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 363 369 4.5E-31 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CIG75_RS17690 1ed42187c85fc38b9242cb76a0dc9629 575 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 52 64 4.5E-31 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CIG75_RS17690 1ed42187c85fc38b9242cb76a0dc9629 575 Gene3D G3DSA:3.50.50.60 2 448 4.2E-57 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS17690 1ed42187c85fc38b9242cb76a0dc9629 575 Pfam PF01266 FAD dependent oxidoreductase 24 378 7.8E-44 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CIG75_RS19865 db77c7aa5f39d5aec13b443d22c5fa4b 242 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 48 70 - T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CIG75_RS19865 db77c7aa5f39d5aec13b443d22c5fa4b 242 Pfam PF01066 CDP-alcohol phosphatidyltransferase 7 70 1.4E-14 T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CIG75_RS19865 db77c7aa5f39d5aec13b443d22c5fa4b 242 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 12 169 2.2E-47 T 28-03-2018 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 CIG75_RS15375 fbdbf8c3e2fe9b42f85f15ed92a39d0c 290 Gene3D G3DSA:3.40.190.10 78 172 5.4E-15 T 28-03-2018 CIG75_RS15375 fbdbf8c3e2fe9b42f85f15ed92a39d0c 290 SUPERFAMILY SSF46785 1 106 2.92E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS15375 fbdbf8c3e2fe9b42f85f15ed92a39d0c 290 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 9.2E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CIG75_RS15375 fbdbf8c3e2fe9b42f85f15ed92a39d0c 290 SUPERFAMILY SSF53850 84 288 5.65E-40 T 28-03-2018 CIG75_RS15375 fbdbf8c3e2fe9b42f85f15ed92a39d0c 290 Gene3D G3DSA:1.10.10.10 1 77 8.8E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS15375 fbdbf8c3e2fe9b42f85f15ed92a39d0c 290 Gene3D G3DSA:3.40.190.10 173 258 1.4E-19 T 28-03-2018 CIG75_RS15375 fbdbf8c3e2fe9b42f85f15ed92a39d0c 290 Pfam PF03466 LysR substrate binding domain 83 287 3.7E-40 T 28-03-2018 IPR005119 LysR, substrate-binding CIG75_RS17950 f19a0595290495b0b2c4b4e861683bd5 336 Pfam PF14285 Domain of unknown function (DUF4367) 232 330 2.3E-5 T 28-03-2018 IPR025377 Domain of unknown function DUF4367 CIG75_RS17950 f19a0595290495b0b2c4b4e861683bd5 336 ProSitePatterns PS00307 Legume lectins beta-chain signature. 188 194 - T 28-03-2018 IPR019825 Legume lectin, beta chain, Mn/Ca-binding site Reactome: R-HSA-196791|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-975634 CIG75_RS17950 f19a0595290495b0b2c4b4e861683bd5 336 SUPERFAMILY SSF89392 34 207 1.22E-12 T 28-03-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX CIG75_RS17950 f19a0595290495b0b2c4b4e861683bd5 336 Gene3D G3DSA:2.50.20.10 29 212 7.2E-18 T 28-03-2018 CIG75_RS17410 e8ab8bf9cf5b4ec077742ae370271d72 409 Gene3D G3DSA:1.10.287.620 27 136 5.2E-6 T 28-03-2018 CIG75_RS17410 e8ab8bf9cf5b4ec077742ae370271d72 409 Gene3D G3DSA:2.70.70.10 203 409 5.8E-46 T 28-03-2018 CIG75_RS17410 e8ab8bf9cf5b4ec077742ae370271d72 409 SUPERFAMILY SSF51261 198 409 3.5E-58 T 28-03-2018 IPR011055 Duplicated hybrid motif CIG75_RS17410 e8ab8bf9cf5b4ec077742ae370271d72 409 Pfam PF01551 Peptidase family M23 309 405 4.1E-32 T 28-03-2018 IPR016047 Peptidase M23 CIG75_RS11280 38d6bae7c84f65f5ed37ce3b9aa27d61 272 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 8 257 2.1E-77 T 28-03-2018 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 CIG75_RS11280 38d6bae7c84f65f5ed37ce3b9aa27d61 272 SUPERFAMILY SSF161098 2 257 5.23E-46 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CIG75_RS11280 38d6bae7c84f65f5ed37ce3b9aa27d61 272 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 66 257 7.2E-14 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CIG75_RS11280 38d6bae7c84f65f5ed37ce3b9aa27d61 272 Gene3D G3DSA:1.10.3720.10 4 263 5.1E-35 T 28-03-2018 CIG75_RS01235 3077d30592918ab6b99b79cdbd9997b5 460 SUPERFAMILY SSF55681 4 372 3.45E-126 T 28-03-2018 CIG75_RS01235 3077d30592918ab6b99b79cdbd9997b5 460 Gene3D G3DSA:3.30.930.10 121 233 2.2E-32 T 28-03-2018 CIG75_RS01235 3077d30592918ab6b99b79cdbd9997b5 460 Gene3D G3DSA:3.30.930.10 234 355 6.3E-45 T 28-03-2018 CIG75_RS01235 3077d30592918ab6b99b79cdbd9997b5 460 Gene3D G3DSA:3.30.930.10 2 108 3.4E-21 T 28-03-2018 CIG75_RS01235 3077d30592918ab6b99b79cdbd9997b5 460 SUPERFAMILY SSF52954 356 458 3.78E-32 T 28-03-2018 IPR004154 Anticodon-binding CIG75_RS01235 3077d30592918ab6b99b79cdbd9997b5 460 Gene3D G3DSA:3.40.50.800 356 459 3.5E-28 T 28-03-2018 IPR004154 Anticodon-binding CIG75_RS01235 3077d30592918ab6b99b79cdbd9997b5 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 168 185 1.7E-54 T 28-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CIG75_RS01235 3077d30592918ab6b99b79cdbd9997b5 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 217 227 1.7E-54 T 28-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CIG75_RS01235 3077d30592918ab6b99b79cdbd9997b5 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 404 423 1.7E-54 T 28-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CIG75_RS01235 3077d30592918ab6b99b79cdbd9997b5 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 147 159 1.7E-54 T 28-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CIG75_RS01235 3077d30592918ab6b99b79cdbd9997b5 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 200 217 1.7E-54 T 28-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CIG75_RS01235 3077d30592918ab6b99b79cdbd9997b5 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 24 38 1.7E-54 T 28-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CIG75_RS01235 3077d30592918ab6b99b79cdbd9997b5 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 324 336 1.7E-54 T 28-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CIG75_RS01235 3077d30592918ab6b99b79cdbd9997b5 460 Pfam PF03129 Anticodon binding domain 369 456 2.5E-22 T 28-03-2018 IPR004154 Anticodon-binding CIG75_RS01235 3077d30592918ab6b99b79cdbd9997b5 460 TIGRFAM TIGR00389 glyS_dimeric: glycine--tRNA ligase 4 240 1.2E-90 T 28-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CIG75_RS01235 3077d30592918ab6b99b79cdbd9997b5 460 Hamap MF_00253_B Glycine--tRNA ligase [glyQS]. 2 459 52.201 T 28-03-2018 IPR022961 Glycine-tRNA ligase, bacterial GO:0004820 KEGG: 00970+6.1.1.14 CIG75_RS01235 3077d30592918ab6b99b79cdbd9997b5 460 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 164 339 3.2E-8 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CIG75_RS11590 fe3b1076a9ec414e85a4aaa8d9c59769 417 SMART SM00852 4 172 1.7E-38 T 28-03-2018 IPR001453 MoaB/Mog domain CIG75_RS11590 fe3b1076a9ec414e85a4aaa8d9c59769 417 SUPERFAMILY SSF142433 252 414 5.49E-57 T 28-03-2018 IPR008136 CinA, C-terminal CIG75_RS11590 fe3b1076a9ec414e85a4aaa8d9c59769 417 Gene3D G3DSA:3.90.950.20 250 417 1.2E-62 T 28-03-2018 CIG75_RS11590 fe3b1076a9ec414e85a4aaa8d9c59769 417 TIGRFAM TIGR00200 cinA_nterm: competence/damage-inducible protein CinA N-terminal domain 1 415 4.1E-136 T 28-03-2018 IPR008135 Competence-induced protein CinA CIG75_RS11590 fe3b1076a9ec414e85a4aaa8d9c59769 417 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 1 163 4.5E-28 T 28-03-2018 IPR001453 MoaB/Mog domain CIG75_RS11590 fe3b1076a9ec414e85a4aaa8d9c59769 417 Hamap MF_00226_B Putative competence-damage inducible protein [cinA]. 1 417 174.074 T 28-03-2018 IPR008135 Competence-induced protein CinA CIG75_RS11590 fe3b1076a9ec414e85a4aaa8d9c59769 417 Pfam PF00994 Probable molybdopterin binding domain 5 170 4.8E-35 T 28-03-2018 IPR001453 MoaB/Mog domain CIG75_RS11590 fe3b1076a9ec414e85a4aaa8d9c59769 417 PIRSF PIRSF006728 1 417 1.2E-160 T 28-03-2018 IPR008135 Competence-induced protein CinA CIG75_RS11590 fe3b1076a9ec414e85a4aaa8d9c59769 417 Pfam PF02464 Competence-damaged protein 259 412 1.2E-59 T 28-03-2018 IPR008136 CinA, C-terminal CIG75_RS11590 fe3b1076a9ec414e85a4aaa8d9c59769 417 Gene3D G3DSA:3.40.980.10 1 172 1.4E-44 T 28-03-2018 IPR001453 MoaB/Mog domain CIG75_RS11590 fe3b1076a9ec414e85a4aaa8d9c59769 417 SUPERFAMILY SSF53218 1 208 7.33E-43 T 28-03-2018 IPR001453 MoaB/Mog domain CIG75_RS11590 fe3b1076a9ec414e85a4aaa8d9c59769 417 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 265 413 4.9E-49 T 28-03-2018 IPR008136 CinA, C-terminal CIG75_RS17050 ead5350dc342392551c8bb7b2511d46c 240 PIRSF PIRSF017388 1 234 5.0E-59 T 28-03-2018 IPR012354 Esterase/lipase GO:0052689 CIG75_RS17050 ead5350dc342392551c8bb7b2511d46c 240 Pfam PF12146 Serine aminopeptidase, S33 2 216 1.1E-22 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 CIG75_RS17050 ead5350dc342392551c8bb7b2511d46c 240 SUPERFAMILY SSF53474 4 232 2.16E-37 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS17050 ead5350dc342392551c8bb7b2511d46c 240 Gene3D G3DSA:3.40.50.1820 2 234 1.1E-38 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS00065 9209fb0c770fe2a0ce05f33ed09ab5b1 200 Gene3D G3DSA:3.40.1360.10 77 172 5.1E-37 T 28-03-2018 CIG75_RS00065 9209fb0c770fe2a0ce05f33ed09ab5b1 200 TIGRFAM TIGR00615 recR: recombination protein RecR 3 198 7.3E-86 T 28-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 CIG75_RS00065 9209fb0c770fe2a0ce05f33ed09ab5b1 200 Hamap MF_00017 Recombination protein RecR [recR]. 1 200 109.506 T 28-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 CIG75_RS00065 9209fb0c770fe2a0ce05f33ed09ab5b1 200 Gene3D G3DSA:1.10.150.20 8 37 0.0057 T 28-03-2018 CIG75_RS00065 9209fb0c770fe2a0ce05f33ed09ab5b1 200 Pfam PF13662 Toprim domain 80 173 1.6E-21 T 28-03-2018 IPR006171 TOPRIM domain CIG75_RS00065 9209fb0c770fe2a0ce05f33ed09ab5b1 200 SUPERFAMILY SSF111304 2 200 6.15E-77 T 28-03-2018 IPR023627 Recombination protein RecR CIG75_RS00065 9209fb0c770fe2a0ce05f33ed09ab5b1 200 Pfam PF02132 RecR protein 40 77 2.1E-16 T 28-03-2018 IPR023628 Recombination protein RecR, C4-type zinc finger CIG75_RS00065 9209fb0c770fe2a0ce05f33ed09ab5b1 200 SMART SM00493 80 167 4.8E-15 T 28-03-2018 IPR006171 TOPRIM domain CIG75_RS07035 79850e27f3b42423bcb39203c1638655 171 SUPERFAMILY SSF56784 5 138 1.78E-25 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS07035 79850e27f3b42423bcb39203c1638655 171 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 28 139 4.5E-18 T 28-03-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 CIG75_RS07035 79850e27f3b42423bcb39203c1638655 171 TIGRFAM TIGR01668 YqeG_hyp_ppase: HAD phosphatase, family IIIA 4 166 1.4E-46 T 28-03-2018 IPR010021 HAD-superfamily phosphatase, YqeG-like CIG75_RS07035 79850e27f3b42423bcb39203c1638655 171 Pfam PF09419 Mitochondrial PGP phosphatase 3 136 1.1E-10 T 28-03-2018 IPR027706 Mitochondrial PGP phosphatase KEGG: 00564+3.1.3.27|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 CIG75_RS07035 79850e27f3b42423bcb39203c1638655 171 Gene3D G3DSA:3.40.50.1000 15 158 4.4E-23 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS06105 78dcf65d6aa25cfef177eb9b2b0343a1 499 Gene3D G3DSA:3.30.70.1380 353 435 5.3E-30 T 28-03-2018 CIG75_RS06105 78dcf65d6aa25cfef177eb9b2b0343a1 499 Hamap MF_01074 UPF0272 protein . 2 498 40.377 T 28-03-2018 IPR002822 Uncharacterised protein family UPF0272 CIG75_RS06105 78dcf65d6aa25cfef177eb9b2b0343a1 499 TIGRFAM TIGR00299 TIGR00299: TIGR00299 family protein 175 488 2.4E-98 T 28-03-2018 IPR002822 Uncharacterised protein family UPF0272 CIG75_RS06105 78dcf65d6aa25cfef177eb9b2b0343a1 499 PRINTS PR00334 HMW kininogen signature 110 133 1.2E-13 T 28-03-2018 IPR002395 HMW kininogen Reactome: R-HSA-114608|Reactome: R-HSA-140837|Reactome: R-HSA-375276|Reactome: R-HSA-381426|Reactome: R-HSA-416476|Reactome: R-HSA-418594|Reactome: R-HSA-8957275 CIG75_RS06105 78dcf65d6aa25cfef177eb9b2b0343a1 499 PRINTS PR00334 HMW kininogen signature 154 176 1.2E-13 T 28-03-2018 IPR002395 HMW kininogen Reactome: R-HSA-114608|Reactome: R-HSA-140837|Reactome: R-HSA-375276|Reactome: R-HSA-381426|Reactome: R-HSA-416476|Reactome: R-HSA-418594|Reactome: R-HSA-8957275 CIG75_RS06105 78dcf65d6aa25cfef177eb9b2b0343a1 499 PRINTS PR00334 HMW kininogen signature 85 106 1.2E-13 T 28-03-2018 IPR002395 HMW kininogen Reactome: R-HSA-114608|Reactome: R-HSA-140837|Reactome: R-HSA-375276|Reactome: R-HSA-381426|Reactome: R-HSA-416476|Reactome: R-HSA-418594|Reactome: R-HSA-8957275 CIG75_RS06105 78dcf65d6aa25cfef177eb9b2b0343a1 499 Gene3D G3DSA:3.10.20.300 437 499 3.6E-17 T 28-03-2018 CIG75_RS06105 78dcf65d6aa25cfef177eb9b2b0343a1 499 Pfam PF01969 Protein of unknown function DUF111 5 488 8.6E-143 T 28-03-2018 IPR035108 LarC/UPF0272 CIG75_RS00265 d0e759ce49f22cac22bc572940a57e4b 285 TIGRFAM TIGR04285 nucleoid_noc: nucleoid occlusion protein 30 282 1.6E-111 T 28-03-2018 IPR023705 Nucleoid occlusion protein CIG75_RS00265 d0e759ce49f22cac22bc572940a57e4b 285 Gene3D G3DSA:1.10.10.730 122 169 1.3E-19 T 28-03-2018 CIG75_RS00265 d0e759ce49f22cac22bc572940a57e4b 285 SUPERFAMILY SSF110849 31 167 3.14E-35 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CIG75_RS00265 d0e759ce49f22cac22bc572940a57e4b 285 SMART SM00470 32 121 1.8E-37 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CIG75_RS00265 d0e759ce49f22cac22bc572940a57e4b 285 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 29 206 9.4E-61 T 28-03-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 CIG75_RS00265 d0e759ce49f22cac22bc572940a57e4b 285 Pfam PF02195 ParB-like nuclease domain 33 120 2.9E-28 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CIG75_RS00265 d0e759ce49f22cac22bc572940a57e4b 285 Gene3D G3DSA:3.90.1530.10 19 121 2.6E-38 T 28-03-2018 CIG75_RS14275 fc1e735fc02e4db10c6b439a8bd41beb 346 Gene3D G3DSA:2.40.110.10 112 204 1.9E-6 T 28-03-2018 CIG75_RS14275 fc1e735fc02e4db10c6b439a8bd41beb 346 SUPERFAMILY SSF56645 9 204 3.24E-23 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CIG75_RS14275 fc1e735fc02e4db10c6b439a8bd41beb 346 Gene3D G3DSA:1.10.540.10 6 104 6.2E-7 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CIG75_RS10950 63462062dd56f98434d016631e7542c3 152 Gene3D G3DSA:3.20.80.10 1 152 3.7E-41 T 28-03-2018 IPR011256 Regulatory factor, effector binding domain CIG75_RS10950 63462062dd56f98434d016631e7542c3 152 SUPERFAMILY SSF55136 1 152 3.84E-31 T 28-03-2018 CIG75_RS10950 63462062dd56f98434d016631e7542c3 152 Pfam PF06445 GyrI-like small molecule binding domain 1 152 1.1E-29 T 28-03-2018 IPR029442 GyrI-like small molecule binding domain CIG75_RS10950 63462062dd56f98434d016631e7542c3 152 SMART SM00871 1 152 1.9E-36 T 28-03-2018 IPR010499 Bacterial transcription activator, effector binding CIG75_RS01695 29391d498a33bfad501383238ca8d2a8 314 Hamap MF_00568 Quinolinate synthase A [nadA]. 14 311 44.009 T 28-03-2018 IPR023066 Quinolinate synthase A, type 2 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 CIG75_RS01695 29391d498a33bfad501383238ca8d2a8 314 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 14 311 2.1E-111 T 28-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 CIG75_RS01695 29391d498a33bfad501383238ca8d2a8 314 Pfam PF02445 Quinolinate synthetase A protein 19 310 1.3E-119 T 28-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 CIG75_RS01695 29391d498a33bfad501383238ca8d2a8 314 Gene3D G3DSA:3.40.50.10800 102 181 3.0E-26 T 28-03-2018 CIG75_RS01695 29391d498a33bfad501383238ca8d2a8 314 SUPERFAMILY SSF142754 15 311 8.76E-119 T 28-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 CIG75_RS01695 29391d498a33bfad501383238ca8d2a8 314 Gene3D G3DSA:3.40.50.10800 182 293 9.4E-30 T 28-03-2018 CIG75_RS01695 29391d498a33bfad501383238ca8d2a8 314 Gene3D G3DSA:3.40.50.10800 14 101 7.1E-22 T 28-03-2018 CIG75_RS01450 9c182ecdc8c2761cca9e1a65f0f4f81f 51 TIGRFAM TIGR03510 XapX: XapX domain 5 50 2.4E-18 T 28-03-2018 IPR020017 XapX domain CIG75_RS01450 9c182ecdc8c2761cca9e1a65f0f4f81f 51 Pfam PF07235 Protein of unknown function (DUF1427) 2 49 9.6E-9 T 28-03-2018 IPR009872 Protein of unknown function DUF1427 CIG75_RS02950 3a457c94daf842ba9449bca20e175865 271 Pfam PF05116 Sucrose-6F-phosphate phosphohydrolase 2 221 9.2E-5 T 28-03-2018 IPR006380 Sucrose-phosphatase-like, N-terminal CIG75_RS02950 3a457c94daf842ba9449bca20e175865 271 SUPERFAMILY SSF56784 2 226 1.07E-12 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS02950 3a457c94daf842ba9449bca20e175865 271 Gene3D G3DSA:3.40.50.1000 1 233 1.3E-6 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS02950 3a457c94daf842ba9449bca20e175865 271 PIRSF PIRSF030802 1 239 4.2E-17 T 28-03-2018 IPR024197 Uncharacterised conserved protein UCP030802 CIG75_RS08395 df572fb7c0b695b9add6173d3e966df4 80 ProDom PD058321 YQZF GSC13 TRANSMEMBRANE IG GKC13 MEMBRANE PROTEINS BH2767 RBL05544 SIMILAR 4 74 1.0E-7 T 28-03-2018 IPR020138 Uncharacterised protein family YqzF CIG75_RS08395 df572fb7c0b695b9add6173d3e966df4 80 Pfam PF11118 Protein of unknown function (DUF2627) 4 74 2.7E-17 T 28-03-2018 IPR020138 Uncharacterised protein family YqzF CIG75_RS02255 3802db9ca02a1430a849425808d97a91 284 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 8 270 1.1E-81 T 28-03-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 CIG75_RS02255 3802db9ca02a1430a849425808d97a91 284 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 280 1.7E-32 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CIG75_RS02255 3802db9ca02a1430a849425808d97a91 284 Gene3D G3DSA:1.10.3720.10 1 271 2.0E-40 T 28-03-2018 CIG75_RS02255 3802db9ca02a1430a849425808d97a91 284 SUPERFAMILY SSF161098 15 269 2.8E-39 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CIG75_RS12520 79f0a04860c97947ffef87ff30a5cd8e 405 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 189 371 2.7E-70 T 28-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CIG75_RS12520 79f0a04860c97947ffef87ff30a5cd8e 405 Pfam PF02441 Flavoprotein 5 176 2.3E-41 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CIG75_RS12520 79f0a04860c97947ffef87ff30a5cd8e 405 Gene3D G3DSA:3.40.50.10300 185 402 1.3E-67 T 28-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CIG75_RS12520 79f0a04860c97947ffef87ff30a5cd8e 405 SUPERFAMILY SSF52507 1 178 7.46E-57 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CIG75_RS12520 79f0a04860c97947ffef87ff30a5cd8e 405 Gene3D G3DSA:3.40.50.1950 1 184 1.1E-51 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CIG75_RS12520 79f0a04860c97947ffef87ff30a5cd8e 405 SUPERFAMILY SSF102645 186 399 8.37E-76 T 28-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CIG75_RS12520 79f0a04860c97947ffef87ff30a5cd8e 405 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 2 395 5.0E-144 T 28-03-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 CIG75_RS15365 4a5571d796f7e7b2bd44588ac6f87caa 178 Gene3D G3DSA:3.40.190.10 1 169 7.0E-6 T 28-03-2018 CIG75_RS17310 8bc92ca9588244e380de46e2ff466cc7 416 Gene3D G3DSA:3.30.930.10 5 338 2.1E-65 T 28-03-2018 CIG75_RS17310 8bc92ca9588244e380de46e2ff466cc7 416 SUPERFAMILY SSF55681 11 329 1.01E-65 T 28-03-2018 CIG75_RS17310 8bc92ca9588244e380de46e2ff466cc7 416 PIRSF PIRSF001549 6 409 1.3E-78 T 28-03-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 CIG75_RS17310 8bc92ca9588244e380de46e2ff466cc7 416 Pfam PF13393 Histidyl-tRNA synthetase 15 324 6.7E-81 T 28-03-2018 CIG75_RS17310 8bc92ca9588244e380de46e2ff466cc7 416 TIGRFAM TIGR00443 hisZ_biosyn_reg: ATP phosphoribosyltransferase, regulatory subunit 17 329 3.2E-100 T 28-03-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 CIG75_RS17310 8bc92ca9588244e380de46e2ff466cc7 416 Hamap MF_00125 ATP phosphoribosyltransferase regulatory subunit [hisZ]. 22 365 28.468 T 28-03-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 CIG75_RS16260 f13307b07636bcaee72d8ba645b2aa69 347 SUPERFAMILY SSF101821 74 186 4.27E-30 T 28-03-2018 CIG75_RS16260 f13307b07636bcaee72d8ba645b2aa69 347 SUPERFAMILY SSF53187 7 86 4.84E-52 T 28-03-2018 CIG75_RS16260 f13307b07636bcaee72d8ba645b2aa69 347 SUPERFAMILY SSF53187 181 344 4.84E-52 T 28-03-2018 CIG75_RS16260 f13307b07636bcaee72d8ba645b2aa69 347 Gene3D G3DSA:3.40.630.10 1 344 1.9E-43 T 28-03-2018 CIG75_RS16260 f13307b07636bcaee72d8ba645b2aa69 347 PIRSF PIRSF001123 6 345 5.8E-36 T 28-03-2018 IPR008007 Peptidase M42 CIG75_RS16260 f13307b07636bcaee72d8ba645b2aa69 347 Pfam PF05343 M42 glutamyl aminopeptidase 51 337 3.9E-81 T 28-03-2018 IPR008007 Peptidase M42 CIG75_RS08440 b7961316da0afcd27a5765dbdd80eee1 585 Gene3D G3DSA:1.10.287.950 219 329 2.1E-7 T 28-03-2018 CIG75_RS08440 b7961316da0afcd27a5765dbdd80eee1 585 Gene3D G3DSA:1.10.287.950 330 580 1.0E-40 T 28-03-2018 CIG75_RS08440 b7961316da0afcd27a5765dbdd80eee1 585 SMART SM00304 392 455 35.0 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CIG75_RS08440 b7961316da0afcd27a5765dbdd80eee1 585 SMART SM00304 221 273 7.7E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CIG75_RS08440 b7961316da0afcd27a5765dbdd80eee1 585 Pfam PF00672 HAMP domain 221 269 2.7E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CIG75_RS08440 b7961316da0afcd27a5765dbdd80eee1 585 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 382 529 1.4E-30 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CIG75_RS08440 b7961316da0afcd27a5765dbdd80eee1 585 Gene3D G3DSA:3.30.450.20 34 191 5.4E-7 T 28-03-2018 CIG75_RS08440 b7961316da0afcd27a5765dbdd80eee1 585 SMART SM00283 302 563 2.0E-41 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CIG75_RS08440 b7961316da0afcd27a5765dbdd80eee1 585 SUPERFAMILY SSF58104 308 571 7.85E-56 T 28-03-2018 CIG75_RS08440 b7961316da0afcd27a5765dbdd80eee1 585 SUPERFAMILY SSF58104 241 275 7.85E-56 T 28-03-2018 CIG75_RS04570 6965f023b6c9ddaace7beea31abb1ddf 602 Gene3D G3DSA:2.130.10.130 439 573 6.4E-11 T 28-03-2018 CIG75_RS04570 6965f023b6c9ddaace7beea31abb1ddf 602 Gene3D G3DSA:2.130.10.130 283 438 9.0E-16 T 28-03-2018 CIG75_RS04570 6965f023b6c9ddaace7beea31abb1ddf 602 Gene3D G3DSA:3.20.20.370 3 282 5.1E-10 T 28-03-2018 CIG75_RS04570 6965f023b6c9ddaace7beea31abb1ddf 602 SUPERFAMILY SSF69318 292 571 2.18E-33 T 28-03-2018 CIG75_RS04570 6965f023b6c9ddaace7beea31abb1ddf 602 Pfam PF10096 Uncharacterized protein conserved in bacteria (DUF2334) 3 270 1.8E-49 T 28-03-2018 IPR018763 Protein of unknown function DUF2334 CIG75_RS04570 6965f023b6c9ddaace7beea31abb1ddf 602 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 413 473 8.4E-9 T 28-03-2018 CIG75_RS03415 183d7a944a481569e4f4736c35a4b5cb 162 Gene3D G3DSA:3.30.450.40 6 141 1.1E-13 T 28-03-2018 IPR029016 GAF domain-like CIG75_RS03415 183d7a944a481569e4f4736c35a4b5cb 162 SUPERFAMILY SSF55781 7 145 2.38E-13 T 28-03-2018 IPR029016 GAF domain-like CIG75_RS07010 3027f12cba85c610dc3f84b112cb3d3b 3165 Gene3D G3DSA:1.10.1200.10 2001 2091 3.5E-21 T 28-03-2018 CIG75_RS07010 3027f12cba85c610dc3f84b112cb3d3b 3165 Gene3D G3DSA:3.40.47.10 1327 1489 4.2E-58 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS07010 3027f12cba85c610dc3f84b112cb3d3b 3165 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1590 1916 9.2E-100 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CIG75_RS07010 3027f12cba85c610dc3f84b112cb3d3b 3165 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1320 1438 3.6E-43 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CIG75_RS07010 3027f12cba85c610dc3f84b112cb3d3b 3165 Pfam PF00550 Phosphopantetheine attachment site 3079 3140 3.7E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS07010 3027f12cba85c610dc3f84b112cb3d3b 3165 Pfam PF00550 Phosphopantetheine attachment site 2019 2081 3.4E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS07010 3027f12cba85c610dc3f84b112cb3d3b 3165 Pfam PF00550 Phosphopantetheine attachment site 973 1034 3.8E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS07010 3027f12cba85c610dc3f84b112cb3d3b 3165 SUPERFAMILY SSF47336 2010 2082 1.22E-18 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS07010 3027f12cba85c610dc3f84b112cb3d3b 3165 Gene3D G3DSA:3.30.559.10 5 208 1.0E-44 T 28-03-2018 CIG75_RS07010 3027f12cba85c610dc3f84b112cb3d3b 3165 Gene3D G3DSA:3.30.70.250 1759 1804 6.4E-15 T 28-03-2018 CIG75_RS07010 3027f12cba85c610dc3f84b112cb3d3b 3165 Pfam PF13193 AMP-binding enzyme C-terminal domain 2981 3051 3.9E-9 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS07010 3027f12cba85c610dc3f84b112cb3d3b 3165 Pfam PF13193 AMP-binding enzyme C-terminal domain 874 942 2.1E-10 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS07010 3027f12cba85c610dc3f84b112cb3d3b 3165 Pfam PF00698 Acyl transferase domain 1589 1898 2.2E-43 T 28-03-2018 IPR014043 Acyl transferase CIG75_RS07010 3027f12cba85c610dc3f84b112cb3d3b 3165 Gene3D G3DSA:1.10.1200.10 976 1061 4.8E-22 T 28-03-2018 CIG75_RS07010 3027f12cba85c610dc3f84b112cb3d3b 3165 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1441 1550 3.0E-17 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS07010 3027f12cba85c610dc3f84b112cb3d3b 3165 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2041 2056 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS07010 3027f12cba85c610dc3f84b112cb3d3b 3165 SUPERFAMILY SSF53901 1466 1483 1.71E-85 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS07010 3027f12cba85c610dc3f84b112cb3d3b 3165 SUPERFAMILY SSF53901 1208 1434 1.71E-85 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS07010 3027f12cba85c610dc3f84b112cb3d3b 3165 SUPERFAMILY SSF53901 1060 1178 1.71E-85 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS07010 3027f12cba85c610dc3f84b112cb3d3b 3165 SMART SM00825 Beta-ketoacyl synthase 1064 1491 1.0E-177 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CIG75_RS07010 3027f12cba85c610dc3f84b112cb3d3b 3165 Gene3D G3DSA:2.30.38.10 778 856 5.3E-20 T 28-03-2018 CIG75_RS07010 3027f12cba85c610dc3f84b112cb3d3b 3165 Gene3D G3DSA:2.30.38.10 2884 2962 2.0E-21 T 28-03-2018 CIG75_RS07010 3027f12cba85c610dc3f84b112cb3d3b 3165 SMART SM00823 Phosphopantetheine attachment site 3077 3146 0.0039 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS07010 3027f12cba85c610dc3f84b112cb3d3b 3165 SMART SM00823 Phosphopantetheine attachment site 2017 2086 7.0E-4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS07010 3027f12cba85c610dc3f84b112cb3d3b 3165 SMART SM00823 Phosphopantetheine attachment site 970 1039 4.1E-4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS07010 3027f12cba85c610dc3f84b112cb3d3b 3165 SUPERFAMILY SSF52777 194 453 4.11E-63 T 28-03-2018 CIG75_RS07010 3027f12cba85c610dc3f84b112cb3d3b 3165 SUPERFAMILY SSF55048 1748 1805 1.14E-7 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CIG75_RS07010 3027f12cba85c610dc3f84b112cb3d3b 3165 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1062 1312 2.5E-69 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CIG75_RS07010 3027f12cba85c610dc3f84b112cb3d3b 3165 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 1230 1248 - T 28-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 CIG75_RS07010 3027f12cba85c610dc3f84b112cb3d3b 3165 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3101 3116 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS07010 3027f12cba85c610dc3f84b112cb3d3b 3165 Gene3D G3DSA:3.30.300.30 2968 3082 1.7E-40 T 28-03-2018 CIG75_RS07010 3027f12cba85c610dc3f84b112cb3d3b 3165 Gene3D G3DSA:3.30.300.30 861 975 6.9E-35 T 28-03-2018 CIG75_RS07010 3027f12cba85c610dc3f84b112cb3d3b 3165 SUPERFAMILY SSF47336 3070 3142 4.19E-20 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS07010 3027f12cba85c610dc3f84b112cb3d3b 3165 SUPERFAMILY SSF47336 962 1035 2.49E-20 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS07010 3027f12cba85c610dc3f84b112cb3d3b 3165 Gene3D G3DSA:3.40.47.10 1062 1323 1.5E-70 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS07010 3027f12cba85c610dc3f84b112cb3d3b 3165 Gene3D G3DSA:3.30.559.10 2092 2297 9.7E-41 T 28-03-2018 CIG75_RS07010 3027f12cba85c610dc3f84b112cb3d3b 3165 SUPERFAMILY SSF52777 2111 2289 4.34E-49 T 28-03-2018 CIG75_RS07010 3027f12cba85c610dc3f84b112cb3d3b 3165 SUPERFAMILY SSF52777 10 186 3.45E-50 T 28-03-2018 CIG75_RS07010 3027f12cba85c610dc3f84b112cb3d3b 3165 Gene3D G3DSA:3.40.50.980 617 777 8.6E-40 T 28-03-2018 CIG75_RS07010 3027f12cba85c610dc3f84b112cb3d3b 3165 Gene3D G3DSA:3.40.50.980 2719 2883 1.9E-41 T 28-03-2018 CIG75_RS07010 3027f12cba85c610dc3f84b112cb3d3b 3165 Gene3D G3DSA:3.40.366.10 1805 1916 2.2E-24 T 28-03-2018 CIG75_RS07010 3027f12cba85c610dc3f84b112cb3d3b 3165 Pfam PF00668 Condensation domain 7 449 4.4E-111 T 28-03-2018 IPR001242 Condensation domain CIG75_RS07010 3027f12cba85c610dc3f84b112cb3d3b 3165 Pfam PF00668 Condensation domain 2107 2553 1.7E-113 T 28-03-2018 IPR001242 Condensation domain CIG75_RS07010 3027f12cba85c610dc3f84b112cb3d3b 3165 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2595 2997 2.3E-132 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS07010 3027f12cba85c610dc3f84b112cb3d3b 3165 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 491 890 9.8E-138 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS07010 3027f12cba85c610dc3f84b112cb3d3b 3165 SUPERFAMILY SSF52151 1587 1640 1.18E-61 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CIG75_RS07010 3027f12cba85c610dc3f84b112cb3d3b 3165 SUPERFAMILY SSF52151 1677 1750 1.18E-61 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CIG75_RS07010 3027f12cba85c610dc3f84b112cb3d3b 3165 SUPERFAMILY SSF52151 1810 1901 1.18E-61 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CIG75_RS07010 3027f12cba85c610dc3f84b112cb3d3b 3165 Gene3D G3DSA:3.40.366.10 1586 1758 1.1E-41 T 28-03-2018 CIG75_RS07010 3027f12cba85c610dc3f84b112cb3d3b 3165 Gene3D G3DSA:1.10.1200.10 3083 3148 3.4E-23 T 28-03-2018 CIG75_RS07010 3027f12cba85c610dc3f84b112cb3d3b 3165 SUPERFAMILY SSF52777 2296 2560 2.89E-67 T 28-03-2018 CIG75_RS07010 3027f12cba85c610dc3f84b112cb3d3b 3165 ProSitePatterns PS00455 Putative AMP-binding domain signature. 611 622 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS07010 3027f12cba85c610dc3f84b112cb3d3b 3165 Gene3D G3DSA:3.40.50.980 2565 2718 8.3E-54 T 28-03-2018 CIG75_RS07010 3027f12cba85c610dc3f84b112cb3d3b 3165 Gene3D G3DSA:3.40.50.980 462 616 3.0E-53 T 28-03-2018 CIG75_RS07010 3027f12cba85c610dc3f84b112cb3d3b 3165 Pfam PF00501 AMP-binding enzyme 470 866 4.5E-106 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS07010 3027f12cba85c610dc3f84b112cb3d3b 3165 Pfam PF00501 AMP-binding enzyme 2574 2973 3.4E-102 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS07010 3027f12cba85c610dc3f84b112cb3d3b 3165 SUPERFAMILY SSF56801 428 983 2.75E-165 T 28-03-2018 CIG75_RS07010 3027f12cba85c610dc3f84b112cb3d3b 3165 SUPERFAMILY SSF56801 2531 3090 6.02E-166 T 28-03-2018 CIG75_RS07010 3027f12cba85c610dc3f84b112cb3d3b 3165 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2713 2724 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS01870 7666bb84110524e0dc4d26f30f2dc2a6 588 ProSitePatterns PS00211 ABC transporters family signature. 482 496 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS01870 7666bb84110524e0dc4d26f30f2dc2a6 588 Pfam PF00664 ABC transporter transmembrane region 35 300 1.6E-49 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CIG75_RS01870 7666bb84110524e0dc4d26f30f2dc2a6 588 SUPERFAMILY SSF90123 20 329 4.97E-74 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CIG75_RS01870 7666bb84110524e0dc4d26f30f2dc2a6 588 Gene3D G3DSA:1.20.1560.10 1 332 8.4E-73 T 28-03-2018 CIG75_RS01870 7666bb84110524e0dc4d26f30f2dc2a6 588 SUPERFAMILY SSF52540 339 581 1.08E-89 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS01870 7666bb84110524e0dc4d26f30f2dc2a6 588 SMART SM00382 369 556 2.1E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS01870 7666bb84110524e0dc4d26f30f2dc2a6 588 Gene3D G3DSA:3.40.50.300 341 577 9.8E-75 T 28-03-2018 CIG75_RS01870 7666bb84110524e0dc4d26f30f2dc2a6 588 Pfam PF00005 ABC transporter 360 510 4.1E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS08790 fe3d824e8b8f2489e5e1f1770a135aa2 214 Pfam PF02163 Peptidase family M50 15 110 5.7E-7 T 28-03-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889|Reactome: R-MMU-8963889 CIG75_RS08790 fe3d824e8b8f2489e5e1f1770a135aa2 214 Pfam PF02163 Peptidase family M50 122 170 1.3E-8 T 28-03-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889|Reactome: R-MMU-8963889 CIG75_RS13495 4fd480a31a8e6a22fb0ca37ab4ddcaad 451 SUPERFAMILY SSF53623 100 309 6.72E-51 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CIG75_RS13495 4fd480a31a8e6a22fb0ca37ab4ddcaad 451 SUPERFAMILY SSF51984 6 97 1.26E-15 T 28-03-2018 CIG75_RS13495 4fd480a31a8e6a22fb0ca37ab4ddcaad 451 Pfam PF02875 Mur ligase family, glutamate ligase domain 312 376 3.1E-8 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CIG75_RS13495 4fd480a31a8e6a22fb0ca37ab4ddcaad 451 SUPERFAMILY SSF53244 311 450 9.16E-43 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CIG75_RS13495 4fd480a31a8e6a22fb0ca37ab4ddcaad 451 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 7 449 1.4E-128 T 28-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CIG75_RS13495 4fd480a31a8e6a22fb0ca37ab4ddcaad 451 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 6 451 35.86 T 28-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CIG75_RS13495 4fd480a31a8e6a22fb0ca37ab4ddcaad 451 Gene3D G3DSA:3.90.190.20 316 450 8.5E-39 T 28-03-2018 CIG75_RS13495 4fd480a31a8e6a22fb0ca37ab4ddcaad 451 Gene3D G3DSA:3.40.50.720 2 98 2.1E-15 T 28-03-2018 CIG75_RS13495 4fd480a31a8e6a22fb0ca37ab4ddcaad 451 Pfam PF08245 Mur ligase middle domain 114 292 1.2E-32 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CIG75_RS13495 4fd480a31a8e6a22fb0ca37ab4ddcaad 451 Gene3D G3DSA:3.40.1190.10 99 309 8.1E-53 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CIG75_RS13890 e57ab17ca09a0afb21bd074816572470 142 Gene3D G3DSA:1.10.940.10 1 134 3.8E-45 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CIG75_RS13890 e57ab17ca09a0afb21bd074816572470 142 Hamap MF_00073 N utilization substance protein B homolog [nusB]. 1 132 23.378 T 28-03-2018 IPR011605 NusB antitermination factor GO:0006353 CIG75_RS13890 e57ab17ca09a0afb21bd074816572470 142 Pfam PF01029 NusB family 5 128 1.6E-37 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CIG75_RS13890 e57ab17ca09a0afb21bd074816572470 142 SUPERFAMILY SSF48013 2 130 2.09E-39 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CIG75_RS13890 e57ab17ca09a0afb21bd074816572470 142 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 2 130 4.2E-42 T 28-03-2018 IPR011605 NusB antitermination factor GO:0006353 CIG75_RS00675 e9969998a9247dc623e3fef2c4314c39 220 Gene3D G3DSA:3.40.50.880 1 220 6.8E-31 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CIG75_RS00675 e9969998a9247dc623e3fef2c4314c39 220 SUPERFAMILY SSF52317 70 215 5.26E-11 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CIG75_RS00675 e9969998a9247dc623e3fef2c4314c39 220 Pfam PF03575 Peptidase family S51 3 209 1.5E-15 T 28-03-2018 IPR005320 Peptidase S51 GO:0006508|GO:0008236 CIG75_RS12880 4857fa9ee6ffd185dc1de77907fc344b 137 SUPERFAMILY SSF103084 1 136 1.57E-25 T 28-03-2018 IPR008822 Crossover junction endodeoxyribonuclease, RusA-like GO:0000287|GO:0006281|GO:0006310 CIG75_RS12880 4857fa9ee6ffd185dc1de77907fc344b 137 Pfam PF05866 Endodeoxyribonuclease RusA 8 134 7.9E-37 T 28-03-2018 IPR008822 Crossover junction endodeoxyribonuclease, RusA-like GO:0000287|GO:0006281|GO:0006310 CIG75_RS12880 4857fa9ee6ffd185dc1de77907fc344b 137 Gene3D G3DSA:3.30.1330.70 1 137 6.7E-35 T 28-03-2018 IPR008822 Crossover junction endodeoxyribonuclease, RusA-like GO:0000287|GO:0006281|GO:0006310 CIG75_RS16265 7f63f924200d30503dca1a308ef7f197 443 Gene3D G3DSA:3.10.450.100 303 440 5.4E-6 T 28-03-2018 CIG75_RS16265 7f63f924200d30503dca1a308ef7f197 443 Pfam PF16111 Domain of unknown function (DUF4829) 307 436 1.5E-12 T 28-03-2018 IPR032256 Domain of unknown function DUF4829 CIG75_RS16265 7f63f924200d30503dca1a308ef7f197 443 Pfam PF16112 Domain of unknown function (DUF4830) 164 258 3.3E-12 T 28-03-2018 IPR032257 Domain of unknown function DUF4830 CIG75_RS05365 fcabb52bcf76c4b7f12affd68ec09ffa 239 SUPERFAMILY SSF56784 4 230 1.16E-28 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS05365 fcabb52bcf76c4b7f12affd68ec09ffa 239 Gene3D G3DSA:3.40.50.1000 2 219 2.8E-22 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS05365 fcabb52bcf76c4b7f12affd68ec09ffa 239 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 115 128 1.0E-6 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CIG75_RS05365 fcabb52bcf76c4b7f12affd68ec09ffa 239 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 149 165 1.0E-6 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CIG75_RS05365 fcabb52bcf76c4b7f12affd68ec09ffa 239 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 194 207 1.0E-6 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CIG75_RS05365 fcabb52bcf76c4b7f12affd68ec09ffa 239 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 1.0E-6 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CIG75_RS05365 fcabb52bcf76c4b7f12affd68ec09ffa 239 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 204 1.9E-10 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS11995 0fe764564f0dd81e250ea8eb196867d8 120 SUPERFAMILY SSF52172 3 119 5.98E-41 T 28-03-2018 IPR011006 CheY-like superfamily CIG75_RS11995 0fe764564f0dd81e250ea8eb196867d8 120 SMART SM00448 3 115 1.1E-41 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CIG75_RS11995 0fe764564f0dd81e250ea8eb196867d8 120 Pfam PF00072 Response regulator receiver domain 5 116 4.0E-35 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CIG75_RS11995 0fe764564f0dd81e250ea8eb196867d8 120 Gene3D G3DSA:3.40.50.2300 1 120 1.5E-40 T 28-03-2018 CIG75_RS04050 354a2631d118e5cbc428a814842796e1 193 SUPERFAMILY SSF55729 3 173 8.58E-40 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CIG75_RS04050 354a2631d118e5cbc428a814842796e1 193 Gene3D G3DSA:3.40.630.30 1 181 1.6E-32 T 28-03-2018 CIG75_RS04050 354a2631d118e5cbc428a814842796e1 193 Pfam PF13302 Acetyltransferase (GNAT) domain 12 149 2.6E-17 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CIG75_RS16155 1f05570d1fc72d6f83356110d559160d 779 SUPERFAMILY SSF52096 470 776 2.26E-33 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CIG75_RS16155 1f05570d1fc72d6f83356110d559160d 779 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 194 293 1.2E-9 T 28-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CIG75_RS16155 1f05570d1fc72d6f83356110d559160d 779 Gene3D G3DSA:3.90.226.10 461 778 2.1E-32 T 28-03-2018 CIG75_RS16155 1f05570d1fc72d6f83356110d559160d 779 Gene3D G3DSA:3.40.50.720 1 191 8.3E-43 T 28-03-2018 CIG75_RS16155 1f05570d1fc72d6f83356110d559160d 779 Gene3D G3DSA:1.10.1040.10 351 437 2.0E-10 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CIG75_RS16155 1f05570d1fc72d6f83356110d559160d 779 SUPERFAMILY SSF51735 4 191 5.79E-44 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS16155 1f05570d1fc72d6f83356110d559160d 779 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 7 191 7.8E-45 T 28-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CIG75_RS16155 1f05570d1fc72d6f83356110d559160d 779 Gene3D G3DSA:1.10.1040.10 192 299 4.0E-15 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CIG75_RS16155 1f05570d1fc72d6f83356110d559160d 779 Pfam PF00378 Enoyl-CoA hydratase/isomerase 485 611 4.8E-9 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CIG75_RS16155 1f05570d1fc72d6f83356110d559160d 779 SUPERFAMILY SSF48179 346 436 2.04E-14 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CIG75_RS16155 1f05570d1fc72d6f83356110d559160d 779 SUPERFAMILY SSF48179 193 312 4.25E-19 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CIG75_RS07245 acc926e855d7ab5629cdf3b3327c6ef0 229 Gene3D G3DSA:3.30.240.20 80 149 2.9E-23 T 28-03-2018 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain CIG75_RS07245 acc926e855d7ab5629cdf3b3327c6ef0 229 Gene3D G3DSA:3.30.240.20 170 225 2.5E-15 T 28-03-2018 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain CIG75_RS07245 acc926e855d7ab5629cdf3b3327c6ef0 229 Pfam PF04239 Protein of unknown function (DUF421) 87 202 2.2E-33 T 28-03-2018 IPR007353 Protein of unknown function DUF421 CIG75_RS19855 d173a6704c09a0a9202562ade1e80de7 231 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 5 222 2.7E-70 T 28-03-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CIG75_RS19855 d173a6704c09a0a9202562ade1e80de7 231 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 2 223 42.316 T 28-03-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CIG75_RS19855 d173a6704c09a0a9202562ade1e80de7 231 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 5 222 9.8E-75 T 28-03-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CIG75_RS19855 d173a6704c09a0a9202562ade1e80de7 231 SUPERFAMILY SSF53448 5 223 4.28E-58 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CIG75_RS19855 d173a6704c09a0a9202562ade1e80de7 231 Gene3D G3DSA:3.90.550.10 1 230 3.1E-50 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CIG75_RS18490 a4f5187fa819f98a5349ee4e00079afd 203 Pfam PF02397 Bacterial sugar transferase 2 176 2.5E-66 T 28-03-2018 IPR003362 Bacterial sugar transferase CIG75_RS07905 623e189b8dc82052fc4dfab48cf885e3 265 Gene3D G3DSA:3.40.50.10090 165 265 9.1E-24 T 28-03-2018 CIG75_RS07905 623e189b8dc82052fc4dfab48cf885e3 265 Gene3D G3DSA:3.40.50.10090 43 164 9.6E-35 T 28-03-2018 CIG75_RS07905 623e189b8dc82052fc4dfab48cf885e3 265 SUPERFAMILY SSF69618 11 261 1.1E-70 T 28-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CIG75_RS07905 623e189b8dc82052fc4dfab48cf885e3 265 Pfam PF02602 Uroporphyrinogen-III synthase HemD 25 255 6.2E-61 T 28-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CIG75_RS17780 1529e991b6dab3f1c1e33b044ab54d63 239 Pfam PF07722 Peptidase C26 3 216 8.5E-61 T 28-03-2018 IPR011697 Peptidase C26 GO:0016787 Reactome: R-HSA-6798695 CIG75_RS17780 1529e991b6dab3f1c1e33b044ab54d63 239 SUPERFAMILY SSF52317 25 236 1.67E-42 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CIG75_RS17780 1529e991b6dab3f1c1e33b044ab54d63 239 Gene3D G3DSA:3.40.50.880 1 239 9.6E-44 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CIG75_RS03020 3d7c210f6dd53f0c8d3ca9b99d839dab 605 Pfam PF13520 Amino acid permease 28 437 1.8E-27 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CIG75_RS01985 509e378b403cc2639a6a6d5071966b56 175 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 24 169 1.7E-35 T 28-03-2018 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CIG75_RS08115 46d7443da8e53ba0c80f66f9b3e330f8 102 ProSitePatterns PS01169 Ribosomal protein L21 signature. 71 93 - T 28-03-2018 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS08115 46d7443da8e53ba0c80f66f9b3e330f8 102 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 102 28.464 T 28-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS08115 46d7443da8e53ba0c80f66f9b3e330f8 102 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 101 4.1E-39 T 28-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS08115 46d7443da8e53ba0c80f66f9b3e330f8 102 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 100 5.4E-43 T 28-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS08115 46d7443da8e53ba0c80f66f9b3e330f8 102 SUPERFAMILY SSF141091 1 101 3.14E-38 T 28-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS00275 1449310b6e437ab6ecacfa6af5739390 282 Pfam PF02195 ParB-like nuclease domain 29 115 1.6E-27 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CIG75_RS00275 1449310b6e437ab6ecacfa6af5739390 282 SMART SM00470 27 116 1.5E-34 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CIG75_RS00275 1449310b6e437ab6ecacfa6af5739390 282 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 27 201 5.6E-63 T 28-03-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 CIG75_RS00275 1449310b6e437ab6ecacfa6af5739390 282 SUPERFAMILY SSF109709 109 219 7.85E-38 T 28-03-2018 CIG75_RS00275 1449310b6e437ab6ecacfa6af5739390 282 Gene3D G3DSA:3.90.1530.10 14 116 3.2E-37 T 28-03-2018 CIG75_RS00275 1449310b6e437ab6ecacfa6af5739390 282 SUPERFAMILY SSF110849 29 118 3.92E-29 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CIG75_RS00275 1449310b6e437ab6ecacfa6af5739390 282 Gene3D G3DSA:1.10.10.730 117 164 1.9E-21 T 28-03-2018 CIG75_RS08555 bc69d6f065d7b663e995337b8b3cfcb2 147 Pfam PF01475 Ferric uptake regulator family 16 135 9.7E-37 T 28-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CIG75_RS08555 bc69d6f065d7b663e995337b8b3cfcb2 147 Gene3D G3DSA:1.10.10.10 8 97 3.1E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS08555 bc69d6f065d7b663e995337b8b3cfcb2 147 SUPERFAMILY SSF46785 6 141 3.63E-37 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS16470 55b22aaba1697d4669d1e15e1113d5c4 328 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 202 285 1.3E-34 T 28-03-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 CIG75_RS16470 55b22aaba1697d4669d1e15e1113d5c4 328 Gene3D G3DSA:3.40.50.1220 198 328 1.2E-58 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CIG75_RS16470 55b22aaba1697d4669d1e15e1113d5c4 328 Gene3D G3DSA:3.40.50.620 1 195 1.1E-43 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CIG75_RS16470 55b22aaba1697d4669d1e15e1113d5c4 328 PIRSF PIRSF000089 1 327 1.8E-110 T 28-03-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 CIG75_RS16470 55b22aaba1697d4669d1e15e1113d5c4 328 Pfam PF01012 Electron transfer flavoprotein domain 6 180 1.2E-42 T 28-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CIG75_RS16470 55b22aaba1697d4669d1e15e1113d5c4 328 SUPERFAMILY SSF52467 202 322 2.0E-48 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CIG75_RS16470 55b22aaba1697d4669d1e15e1113d5c4 328 SMART SM00893 5 191 8.2E-42 T 28-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CIG75_RS16470 55b22aaba1697d4669d1e15e1113d5c4 328 SUPERFAMILY SSF52402 4 198 7.67E-46 T 28-03-2018 CIG75_RS10880 5bd0db8b1e2a1cb755b5e4390531e282 290 SUPERFAMILY SSF51735 6 174 3.87E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS10880 5bd0db8b1e2a1cb755b5e4390531e282 290 SUPERFAMILY SSF48179 177 289 1.13E-30 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CIG75_RS10880 5bd0db8b1e2a1cb755b5e4390531e282 290 Gene3D G3DSA:1.10.3660.10 185 290 5.7E-22 T 28-03-2018 CIG75_RS10880 5bd0db8b1e2a1cb755b5e4390531e282 290 Pfam PF02153 Prephenate dehydrogenase 19 278 1.8E-71 T 28-03-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 CIG75_RS10880 5bd0db8b1e2a1cb755b5e4390531e282 290 Gene3D G3DSA:3.40.50.720 4 175 1.8E-29 T 28-03-2018 CIG75_RS04445 84ae650427db8002ba6aeacc357666f2 275 Gene3D G3DSA:3.90.226.10 5 232 5.9E-71 T 28-03-2018 CIG75_RS04445 84ae650427db8002ba6aeacc357666f2 275 Gene3D G3DSA:1.10.12.10 233 275 4.3E-15 T 28-03-2018 IPR014748 Crontonase, C-terminal CIG75_RS04445 84ae650427db8002ba6aeacc357666f2 275 SUPERFAMILY SSF52096 4 275 3.58E-89 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CIG75_RS04445 84ae650427db8002ba6aeacc357666f2 275 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 274 8.9E-64 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CIG75_RS04445 84ae650427db8002ba6aeacc357666f2 275 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 116 136 - T 28-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CIG75_RS01630 606bcb8f4fa028af4288f3a2f8eeb758 313 SUPERFAMILY SSF52540 2 309 6.71E-77 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS01630 606bcb8f4fa028af4288f3a2f8eeb758 313 Pfam PF03308 ArgK protein 17 278 1.9E-95 T 28-03-2018 CIG75_RS01630 606bcb8f4fa028af4288f3a2f8eeb758 313 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 11 307 5.6E-103 T 28-03-2018 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CIG75_RS01630 606bcb8f4fa028af4288f3a2f8eeb758 313 Gene3D G3DSA:3.40.50.300 42 248 4.4E-34 T 28-03-2018 CIG75_RS01630 606bcb8f4fa028af4288f3a2f8eeb758 313 Gene3D G3DSA:1.20.5.170 3 40 6.7E-10 T 28-03-2018 CIG75_RS08575 58c51a5041e46b2d2d0bcbf0a3c31e32 391 SUPERFAMILY SSF53649 2 100 1.83E-68 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CIG75_RS08575 58c51a5041e46b2d2d0bcbf0a3c31e32 391 SUPERFAMILY SSF53649 215 388 1.83E-68 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CIG75_RS08575 58c51a5041e46b2d2d0bcbf0a3c31e32 391 PIRSF PIRSF001491 2 389 4.0E-154 T 28-03-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 CIG75_RS08575 58c51a5041e46b2d2d0bcbf0a3c31e32 391 Hamap MF_00740 Phosphopentomutase [deoB]. 3 385 52.795 T 28-03-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 CIG75_RS08575 58c51a5041e46b2d2d0bcbf0a3c31e32 391 Pfam PF01676 Metalloenzyme superfamily 5 376 9.1E-38 T 28-03-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 CIG75_RS08575 58c51a5041e46b2d2d0bcbf0a3c31e32 391 Gene3D G3DSA:3.30.70.1250 99 208 5.7E-55 T 28-03-2018 IPR024052 Phosphopentomutase DeoB cap domain GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 CIG75_RS08575 58c51a5041e46b2d2d0bcbf0a3c31e32 391 TIGRFAM TIGR01696 deoB: phosphopentomutase 5 382 8.7E-161 T 28-03-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 CIG75_RS08575 58c51a5041e46b2d2d0bcbf0a3c31e32 391 Gene3D G3DSA:3.40.720.10 209 379 6.0E-16 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CIG75_RS08575 58c51a5041e46b2d2d0bcbf0a3c31e32 391 SUPERFAMILY SSF143856 101 214 3.01E-50 T 28-03-2018 IPR024052 Phosphopentomutase DeoB cap domain GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 CIG75_RS08995 8a9aceace9636941c5f82caa3f263927 586 PRINTS PR00775 90kDa heat shock protein signature 93 115 5.9E-13 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CIG75_RS08995 8a9aceace9636941c5f82caa3f263927 586 PRINTS PR00775 90kDa heat shock protein signature 11 33 5.9E-13 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CIG75_RS08995 8a9aceace9636941c5f82caa3f263927 586 PRINTS PR00775 90kDa heat shock protein signature 144 161 5.9E-13 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CIG75_RS08995 8a9aceace9636941c5f82caa3f263927 586 PRINTS PR00775 90kDa heat shock protein signature 162 180 5.9E-13 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CIG75_RS08995 8a9aceace9636941c5f82caa3f263927 586 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 14 125 4.3E-11 T 28-03-2018 CIG75_RS08995 8a9aceace9636941c5f82caa3f263927 586 Gene3D G3DSA:3.30.565.10 1 195 3.3E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS08995 8a9aceace9636941c5f82caa3f263927 586 SUPERFAMILY SSF54211 195 428 1.97E-34 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CIG75_RS08995 8a9aceace9636941c5f82caa3f263927 586 Pfam PF00183 Hsp90 protein 251 374 2.3E-9 T 28-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 CIG75_RS08995 8a9aceace9636941c5f82caa3f263927 586 SUPERFAMILY SSF55874 2 182 1.05E-35 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS08995 8a9aceace9636941c5f82caa3f263927 586 PIRSF PIRSF002583 1 585 2.4E-95 T 28-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 CIG75_RS01675 e486de7c0e53fd3efbe706da6e19652a 179 Gene3D G3DSA:3.40.50.2020 1 179 1.5E-47 T 28-03-2018 CIG75_RS01675 e486de7c0e53fd3efbe706da6e19652a 179 Pfam PF00156 Phosphoribosyl transferase domain 7 159 1.2E-27 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CIG75_RS01675 e486de7c0e53fd3efbe706da6e19652a 179 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 8 173 2.1E-70 T 28-03-2018 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 CIG75_RS01675 e486de7c0e53fd3efbe706da6e19652a 179 SUPERFAMILY SSF53271 1 177 4.2E-61 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CIG75_RS10050 63fa5bf07efc519dc1b32791f375908f 292 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS10050 63fa5bf07efc519dc1b32791f375908f 292 SMART SM00382 27 210 1.3E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS10050 63fa5bf07efc519dc1b32791f375908f 292 SUPERFAMILY SSF52540 4 223 1.64E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS10050 63fa5bf07efc519dc1b32791f375908f 292 Pfam PF00005 ABC transporter 19 163 1.4E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS10050 63fa5bf07efc519dc1b32791f375908f 292 Gene3D G3DSA:3.40.50.300 1 257 3.0E-63 T 28-03-2018 CIG75_RS07430 3262d48192c716b9b9970e21455109ac 142 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 41 57 - T 28-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CIG75_RS07430 3262d48192c716b9b9970e21455109ac 142 SUPERFAMILY SSF56014 19 133 4.32E-24 T 28-03-2018 CIG75_RS07430 3262d48192c716b9b9970e21455109ac 142 Gene3D G3DSA:3.30.413.10 6 142 7.2E-21 T 28-03-2018 CIG75_RS07430 3262d48192c716b9b9970e21455109ac 142 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 29 129 5.0E-7 T 28-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CIG75_RS08300 87d25576328c6bb788fcf14ab0b95486 408 Gene3D G3DSA:1.20.1250.20 216 407 1.2E-23 T 28-03-2018 CIG75_RS08300 87d25576328c6bb788fcf14ab0b95486 408 SUPERFAMILY SSF103473 10 396 2.49E-57 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS08300 87d25576328c6bb788fcf14ab0b95486 408 Gene3D G3DSA:1.20.1250.20 2 213 3.3E-22 T 28-03-2018 CIG75_RS08300 87d25576328c6bb788fcf14ab0b95486 408 Pfam PF07690 Major Facilitator Superfamily 24 361 9.7E-35 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CIG75_RS13950 1417987fda888bc8a7ee3261858f3540 172 PIRSF PIRSF021435 1 172 8.4E-53 T 28-03-2018 IPR014198 Stage III sporulation protein AB CIG75_RS13950 1417987fda888bc8a7ee3261858f3540 172 Pfam PF09548 Stage III sporulation protein AB (spore_III_AB) 3 171 1.6E-54 T 28-03-2018 IPR014198 Stage III sporulation protein AB CIG75_RS13950 1417987fda888bc8a7ee3261858f3540 172 TIGRFAM TIGR02833 spore_III_AB: stage III sporulation protein AB 3 171 2.7E-56 T 28-03-2018 IPR014198 Stage III sporulation protein AB CIG75_RS19860 2159931f0ce7a51300093b83a4ebc655 358 Pfam PF01938 TRAM domain 290 342 1.2E-4 T 28-03-2018 IPR002792 TRAM domain CIG75_RS19860 2159931f0ce7a51300093b83a4ebc655 358 SMART SM00670 158 265 1.5E-13 T 28-03-2018 IPR002716 PIN domain CIG75_RS19860 2159931f0ce7a51300093b83a4ebc655 358 SUPERFAMILY SSF88723 160 286 6.21E-24 T 28-03-2018 IPR029060 PIN domain-like CIG75_RS19860 2159931f0ce7a51300093b83a4ebc655 358 Gene3D G3DSA:3.40.50.1010 157 289 1.4E-25 T 28-03-2018 IPR029060 PIN domain-like CIG75_RS12455 0f7ad0661a00a3ab767aca68d03bf18c 558 SUPERFAMILY SSF101473 2 200 1.27E-44 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CIG75_RS12455 0f7ad0661a00a3ab767aca68d03bf18c 558 Pfam PF02734 DAK2 domain 34 199 4.9E-43 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CIG75_RS12455 0f7ad0661a00a3ab767aca68d03bf18c 558 Pfam PF13684 Dihydroxyacetone kinase family 234 558 5.4E-115 T 28-03-2018 IPR033470 Uncharacterised protein, DhaK domain CIG75_RS12455 0f7ad0661a00a3ab767aca68d03bf18c 558 SMART SM01120 34 200 6.1E-68 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CIG75_RS12455 0f7ad0661a00a3ab767aca68d03bf18c 558 SMART SM01121 234 558 1.3E-148 T 28-03-2018 IPR033470 Uncharacterised protein, DhaK domain CIG75_RS12455 0f7ad0661a00a3ab767aca68d03bf18c 558 TIGRFAM TIGR03599 YloV: DAK2 domain fusion protein YloV 9 558 4.2E-199 T 28-03-2018 IPR019986 DAK2 domain-containing protein YloV CIG75_RS15265 5d56d72fa0e3fa58d13a3ec073855df7 358 Pfam PF05343 M42 glutamyl aminopeptidase 45 339 5.2E-97 T 28-03-2018 IPR008007 Peptidase M42 CIG75_RS15265 5d56d72fa0e3fa58d13a3ec073855df7 358 Gene3D G3DSA:3.40.630.10 171 357 2.3E-41 T 28-03-2018 CIG75_RS15265 5d56d72fa0e3fa58d13a3ec073855df7 358 SUPERFAMILY SSF101821 70 179 3.51E-32 T 28-03-2018 CIG75_RS15265 5d56d72fa0e3fa58d13a3ec073855df7 358 PIRSF PIRSF001123 1 358 1.2E-127 T 28-03-2018 IPR008007 Peptidase M42 CIG75_RS15265 5d56d72fa0e3fa58d13a3ec073855df7 358 SUPERFAMILY SSF53187 4 80 4.02E-62 T 28-03-2018 CIG75_RS15265 5d56d72fa0e3fa58d13a3ec073855df7 358 SUPERFAMILY SSF53187 171 354 4.02E-62 T 28-03-2018 CIG75_RS15265 5d56d72fa0e3fa58d13a3ec073855df7 358 Gene3D G3DSA:2.40.30.40 69 160 2.7E-33 T 28-03-2018 IPR023367 Peptidase M42, domain 2 CIG75_RS07665 12164904bc5b17bf2f5906c3d69077fa 216 Gene3D G3DSA:3.30.70.260 144 203 8.2E-8 T 28-03-2018 CIG75_RS07665 12164904bc5b17bf2f5906c3d69077fa 216 SUPERFAMILY SSF54631 1 131 3.54E-33 T 28-03-2018 CIG75_RS07665 12164904bc5b17bf2f5906c3d69077fa 216 SUPERFAMILY SSF55021 139 201 8.74E-8 T 28-03-2018 CIG75_RS07665 12164904bc5b17bf2f5906c3d69077fa 216 Pfam PF00571 CBS domain 3 55 2.3E-12 T 28-03-2018 IPR000644 CBS domain CIG75_RS07665 12164904bc5b17bf2f5906c3d69077fa 216 Pfam PF00571 CBS domain 74 128 3.2E-13 T 28-03-2018 IPR000644 CBS domain CIG75_RS07665 12164904bc5b17bf2f5906c3d69077fa 216 SMART SM00116 10 57 2.0E-9 T 28-03-2018 IPR000644 CBS domain CIG75_RS07665 12164904bc5b17bf2f5906c3d69077fa 216 SMART SM00116 81 128 2.3E-12 T 28-03-2018 IPR000644 CBS domain CIG75_RS07665 12164904bc5b17bf2f5906c3d69077fa 216 Gene3D G3DSA:3.10.580.10 1 143 1.1E-29 T 28-03-2018 CIG75_RS06340 e66b27bceb69577727b82088cb6bf58f 693 Pfam PF08486 Stage II sporulation protein 293 382 1.2E-23 T 28-03-2018 IPR013693 Sporulation stage II protein D, amidase enhancer LytB N-terminal CIG75_RS06340 e66b27bceb69577727b82088cb6bf58f 693 Pfam PF05036 Sporulation related domain 95 165 2.6E-8 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 CIG75_RS06340 e66b27bceb69577727b82088cb6bf58f 693 SUPERFAMILY SSF110997 96 160 5.36E-6 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 CIG75_RS06340 e66b27bceb69577727b82088cb6bf58f 693 TIGRFAM TIGR02669 SpoIID_LytB: SpoIID/LytB domain 298 426 2.7E-41 T 28-03-2018 IPR013486 Sporulation stage II protein D, amidase enhancer LytB GO:0030435 CIG75_RS06340 e66b27bceb69577727b82088cb6bf58f 693 Gene3D G3DSA:3.30.70.1070 96 162 9.0E-6 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 CIG75_RS06340 e66b27bceb69577727b82088cb6bf58f 693 Gene3D G3DSA:3.30.70.1070 165 231 4.9E-4 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 CIG75_RS06515 e8dc18be4c0e29e80d8969a586b89ff6 142 SUPERFAMILY SSF54427 22 139 7.21E-16 T 28-03-2018 IPR032710 NTF2-like domain CIG75_RS06515 e8dc18be4c0e29e80d8969a586b89ff6 142 Pfam PF13474 SnoaL-like domain 25 137 3.0E-8 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CIG75_RS06515 e8dc18be4c0e29e80d8969a586b89ff6 142 Gene3D G3DSA:3.10.450.50 10 142 9.5E-10 T 28-03-2018 CIG75_RS11625 eb6262cf724bf04029ff735a4a91e551 260 Gene3D G3DSA:3.30.70.260 12 79 2.0E-6 T 28-03-2018 CIG75_RS11625 eb6262cf724bf04029ff735a4a91e551 260 Pfam PF11868 Protein of unknown function (DUF3388) 73 251 1.1E-79 T 28-03-2018 IPR024514 Domain of unknown function DUF3388 CIG75_RS11625 eb6262cf724bf04029ff735a4a91e551 260 PIRSF PIRSF021288 2 258 4.1E-109 T 28-03-2018 IPR016784 Uncharacterised protein UCP021288 with ACT domain CIG75_RS11625 eb6262cf724bf04029ff735a4a91e551 260 SUPERFAMILY SSF55021 6 74 5.83E-10 T 28-03-2018 CIG75_RS19775 6f2e736a4e36a41c7351ad870b9f32f6 202 Gene3D G3DSA:3.40.50.150 12 200 1.6E-33 T 28-03-2018 CIG75_RS19775 6f2e736a4e36a41c7351ad870b9f32f6 202 Pfam PF05175 Methyltransferase small domain 28 194 7.4E-49 T 28-03-2018 IPR007848 Methyltransferase small domain GO:0008168 CIG75_RS19775 6f2e736a4e36a41c7351ad870b9f32f6 202 SUPERFAMILY SSF53335 7 193 1.01E-39 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CIG75_RS16030 b321acca3cd8fe252ef31ad24c293bd8 297 Gene3D G3DSA:1.10.10.10 3 82 9.2E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS16030 b321acca3cd8fe252ef31ad24c293bd8 297 SUPERFAMILY SSF46785 4 111 5.39E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS16030 b321acca3cd8fe252ef31ad24c293bd8 297 Pfam PF03466 LysR substrate binding domain 88 291 4.1E-50 T 28-03-2018 IPR005119 LysR, substrate-binding CIG75_RS16030 b321acca3cd8fe252ef31ad24c293bd8 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 5.9E-11 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CIG75_RS16030 b321acca3cd8fe252ef31ad24c293bd8 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 5.9E-11 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CIG75_RS16030 b321acca3cd8fe252ef31ad24c293bd8 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 5.9E-11 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CIG75_RS16030 b321acca3cd8fe252ef31ad24c293bd8 297 Gene3D G3DSA:3.40.190.10 87 177 3.4E-23 T 28-03-2018 CIG75_RS16030 b321acca3cd8fe252ef31ad24c293bd8 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 4.2E-22 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CIG75_RS16030 b321acca3cd8fe252ef31ad24c293bd8 297 Gene3D G3DSA:3.40.190.10 178 265 1.4E-23 T 28-03-2018 CIG75_RS16030 b321acca3cd8fe252ef31ad24c293bd8 297 SUPERFAMILY SSF53850 89 293 9.87E-47 T 28-03-2018 CIG75_RS15465 67157439f5382504d6f682f7e3997b91 336 SUPERFAMILY SSF103481 64 167 1.96E-15 T 28-03-2018 CIG75_RS15465 67157439f5382504d6f682f7e3997b91 336 SUPERFAMILY SSF103481 237 315 5.1E-10 T 28-03-2018 CIG75_RS15465 67157439f5382504d6f682f7e3997b91 336 Pfam PF00892 EamA-like transporter family 33 163 1.7E-22 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CIG75_RS15465 67157439f5382504d6f682f7e3997b91 336 Pfam PF00892 EamA-like transporter family 178 315 1.8E-17 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CIG75_RS01905 9fb7de64235a5007c189aa57c568147b 394 Pfam PF02803 Thiolase, C-terminal domain 273 394 2.9E-50 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CIG75_RS01905 9fb7de64235a5007c189aa57c568147b 394 SUPERFAMILY SSF53901 274 394 5.41E-43 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS01905 9fb7de64235a5007c189aa57c568147b 394 ProSitePatterns PS00737 Thiolases signature 2. 341 357 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CIG75_RS01905 9fb7de64235a5007c189aa57c568147b 394 Pfam PF00108 Thiolase, N-terminal domain 7 265 4.0E-109 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CIG75_RS01905 9fb7de64235a5007c189aa57c568147b 394 SUPERFAMILY SSF53901 5 272 1.05E-92 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS01905 9fb7de64235a5007c189aa57c568147b 394 Gene3D G3DSA:3.40.47.10 3 267 2.0E-67 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS01905 9fb7de64235a5007c189aa57c568147b 394 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 8 393 1.2E-149 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CIG75_RS01905 9fb7de64235a5007c189aa57c568147b 394 PIRSF PIRSF000429 1 394 1.7E-137 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CIG75_RS01905 9fb7de64235a5007c189aa57c568147b 394 ProSitePatterns PS00099 Thiolases active site. 376 389 - T 28-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 CIG75_RS01905 9fb7de64235a5007c189aa57c568147b 394 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 86 104 - T 28-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 CIG75_RS01905 9fb7de64235a5007c189aa57c568147b 394 Gene3D G3DSA:3.40.47.10 268 392 5.1E-38 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS04325 a549e2543d4874e0278889d8d5911807 402 Gene3D G3DSA:3.40.50.200 94 402 1.5E-63 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CIG75_RS04325 a549e2543d4874e0278889d8d5911807 402 SUPERFAMILY SSF52743 139 399 4.06E-62 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CIG75_RS04325 a549e2543d4874e0278889d8d5911807 402 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 163 174 - T 28-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site CIG75_RS04325 a549e2543d4874e0278889d8d5911807 402 PRINTS PR00723 Subtilisin serine protease family (S8) signature 158 177 1.6E-13 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CIG75_RS04325 a549e2543d4874e0278889d8d5911807 402 PRINTS PR00723 Subtilisin serine protease family (S8) signature 346 362 1.6E-13 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CIG75_RS04325 a549e2543d4874e0278889d8d5911807 402 PRINTS PR00723 Subtilisin serine protease family (S8) signature 196 209 1.6E-13 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CIG75_RS04325 a549e2543d4874e0278889d8d5911807 402 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 200 210 - T 28-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site CIG75_RS04325 a549e2543d4874e0278889d8d5911807 402 Pfam PF00082 Subtilase family 162 385 1.5E-25 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CIG75_RS02525 898a1838f6c73413150e1d881e96ae5d 610 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 610 40.565 T 28-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 CIG75_RS02525 898a1838f6c73413150e1d881e96ae5d 610 Gene3D G3DSA:3.40.50.10490 240 459 4.5E-68 T 28-03-2018 CIG75_RS02525 898a1838f6c73413150e1d881e96ae5d 610 Pfam PF01380 SIS domain 463 592 1.3E-23 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CIG75_RS02525 898a1838f6c73413150e1d881e96ae5d 610 Pfam PF01380 SIS domain 295 417 2.7E-28 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CIG75_RS02525 898a1838f6c73413150e1d881e96ae5d 610 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 610 5.0E-246 T 28-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 CIG75_RS02525 898a1838f6c73413150e1d881e96ae5d 610 SUPERFAMILY SSF56235 2 234 4.8E-73 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CIG75_RS02525 898a1838f6c73413150e1d881e96ae5d 610 Pfam PF13522 Glutamine amidotransferase domain 65 183 3.2E-22 T 28-03-2018 CIG75_RS02525 898a1838f6c73413150e1d881e96ae5d 610 SUPERFAMILY SSF53697 245 610 2.6E-107 T 28-03-2018 CIG75_RS02525 898a1838f6c73413150e1d881e96ae5d 610 Gene3D G3DSA:3.40.50.10490 460 608 1.3E-43 T 28-03-2018 CIG75_RS02525 898a1838f6c73413150e1d881e96ae5d 610 Gene3D G3DSA:3.60.20.10 2 239 2.2E-66 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CIG75_RS11695 14dcf6f98d79339aa2d7507146d4bce6 847 Pfam PF09397 Ftsk gamma domain 773 833 4.5E-27 T 28-03-2018 IPR018541 FtsK gamma domain CIG75_RS11695 14dcf6f98d79339aa2d7507146d4bce6 847 SMART SM00382 518 694 4.2E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS11695 14dcf6f98d79339aa2d7507146d4bce6 847 SUPERFAMILY SSF46785 771 837 8.38E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS11695 14dcf6f98d79339aa2d7507146d4bce6 847 Pfam PF01580 FtsK/SpoIIIE family 483 619 5.1E-45 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CIG75_RS11695 14dcf6f98d79339aa2d7507146d4bce6 847 Pfam PF01580 FtsK/SpoIIIE family 622 673 2.4E-17 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CIG75_RS11695 14dcf6f98d79339aa2d7507146d4bce6 847 Gene3D G3DSA:1.10.10.10 773 827 4.1E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS11695 14dcf6f98d79339aa2d7507146d4bce6 847 SUPERFAMILY SSF52540 456 743 1.08E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS11695 14dcf6f98d79339aa2d7507146d4bce6 847 SMART SM00843 771 836 3.3E-35 T 28-03-2018 IPR018541 FtsK gamma domain CIG75_RS11695 14dcf6f98d79339aa2d7507146d4bce6 847 Gene3D G3DSA:3.40.50.300 222 751 3.0E-55 T 28-03-2018 CIG75_RS14140 521f2a6fd3d011d58e1e892ab099e17e 519 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 101 248 4.4E-44 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CIG75_RS14140 521f2a6fd3d011d58e1e892ab099e17e 519 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 100 248 2.9E-40 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CIG75_RS03725 0a79b10b10abaa59960cc31b1b829c9f 212 Pfam PF02525 Flavodoxin-like fold 3 200 1.4E-44 T 28-03-2018 IPR003680 Flavodoxin-like fold CIG75_RS03725 0a79b10b10abaa59960cc31b1b829c9f 212 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 2 211 29.867 T 28-03-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 CIG75_RS03725 0a79b10b10abaa59960cc31b1b829c9f 212 Gene3D G3DSA:3.40.50.360 3 212 1.1E-41 T 28-03-2018 IPR029039 Flavoprotein-like domain CIG75_RS03725 0a79b10b10abaa59960cc31b1b829c9f 212 SUPERFAMILY SSF52218 1 211 2.01E-51 T 28-03-2018 IPR029039 Flavoprotein-like domain CIG75_RS04005 799b19b3f54055a5c104e3e03393b00d 182 Gene3D G3DSA:1.10.10.10 86 171 1.8E-33 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS04005 799b19b3f54055a5c104e3e03393b00d 182 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 140 146 - T 28-03-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CIG75_RS04005 799b19b3f54055a5c104e3e03393b00d 182 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 90 169 1.0E-36 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CIG75_RS04005 799b19b3f54055a5c104e3e03393b00d 182 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 91 169 2.5E-32 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CIG75_RS04005 799b19b3f54055a5c104e3e03393b00d 182 SUPERFAMILY SSF53155 9 87 3.73E-12 T 28-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CIG75_RS04005 799b19b3f54055a5c104e3e03393b00d 182 SUPERFAMILY SSF46767 89 170 7.32E-32 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CIG75_RS04005 799b19b3f54055a5c104e3e03393b00d 182 Gene3D G3DSA:3.30.160.70 2 85 2.9E-9 T 28-03-2018 CIG75_RS01945 4aca7def57a3be77193019b53d410216 469 SUPERFAMILY SSF50615 2 82 5.76E-28 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CIG75_RS01945 4aca7def57a3be77193019b53d410216 469 Gene3D G3DSA:1.10.1140.10 356 466 6.2E-41 T 28-03-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CIG75_RS01945 4aca7def57a3be77193019b53d410216 469 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 137 350 9.6E-66 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CIG75_RS01945 4aca7def57a3be77193019b53d410216 469 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 6 80 2.5E-22 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CIG75_RS01945 4aca7def57a3be77193019b53d410216 469 SMART SM00382 149 335 2.1E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS01945 4aca7def57a3be77193019b53d410216 469 Gene3D G3DSA:3.40.50.300 83 355 8.6E-92 T 28-03-2018 CIG75_RS01945 4aca7def57a3be77193019b53d410216 469 SUPERFAMILY SSF52540 84 355 2.55E-90 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS01945 4aca7def57a3be77193019b53d410216 469 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 341 350 - T 28-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CIG75_RS01945 4aca7def57a3be77193019b53d410216 469 Hamap MF_01347 ATP synthase subunit beta [atpB]. 1 468 57.478 T 28-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 CIG75_RS01945 4aca7def57a3be77193019b53d410216 469 Gene3D G3DSA:2.40.10.170 1 82 4.4E-32 T 28-03-2018 CIG75_RS01945 4aca7def57a3be77193019b53d410216 469 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 3 467 3.1E-251 T 28-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 CIG75_RS01945 4aca7def57a3be77193019b53d410216 469 SUPERFAMILY SSF47917 353 467 4.19E-50 T 28-03-2018 CIG75_RS18070 23c0a4fa25ee969eac5523698ba9d720 445 SUPERFAMILY SSF52777 209 442 6.23E-87 T 28-03-2018 CIG75_RS18070 23c0a4fa25ee969eac5523698ba9d720 445 Pfam PF00364 Biotin-requiring enzyme 5 76 2.3E-20 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CIG75_RS18070 23c0a4fa25ee969eac5523698ba9d720 445 SUPERFAMILY SSF47005 85 126 1.06E-11 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CIG75_RS18070 23c0a4fa25ee969eac5523698ba9d720 445 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 214 442 2.2E-89 T 28-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CIG75_RS18070 23c0a4fa25ee969eac5523698ba9d720 445 Gene3D G3DSA:2.40.50.100 1 80 4.1E-15 T 28-03-2018 CIG75_RS18070 23c0a4fa25ee969eac5523698ba9d720 445 Gene3D G3DSA:3.30.559.10 197 442 3.4E-90 T 28-03-2018 CIG75_RS18070 23c0a4fa25ee969eac5523698ba9d720 445 Pfam PF02817 e3 binding domain 88 123 4.9E-14 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CIG75_RS18070 23c0a4fa25ee969eac5523698ba9d720 445 Gene3D G3DSA:4.10.320.10 81 149 3.6E-18 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CIG75_RS18070 23c0a4fa25ee969eac5523698ba9d720 445 SUPERFAMILY SSF51230 2 86 3.66E-25 T 28-03-2018 IPR011053 Single hybrid motif CIG75_RS11060 2dcc2fbb861012a72fd23f49e3fd3182 480 SUPERFAMILY SSF52777 233 475 4.39E-56 T 28-03-2018 CIG75_RS11060 2dcc2fbb861012a72fd23f49e3fd3182 480 Gene3D G3DSA:3.30.559.10 38 249 1.8E-42 T 28-03-2018 CIG75_RS11060 2dcc2fbb861012a72fd23f49e3fd3182 480 SUPERFAMILY SSF52777 50 227 1.41E-47 T 28-03-2018 CIG75_RS11060 2dcc2fbb861012a72fd23f49e3fd3182 480 Pfam PF00668 Condensation domain 49 477 2.5E-98 T 28-03-2018 IPR001242 Condensation domain CIG75_RS03005 93e32450a8ed243588604bd53352c3fb 203 Pfam PF13847 Methyltransferase domain 36 143 2.0E-15 T 28-03-2018 IPR025714 Methyltransferase domain CIG75_RS03005 93e32450a8ed243588604bd53352c3fb 203 SUPERFAMILY SSF53335 33 203 4.6E-30 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CIG75_RS03005 93e32450a8ed243588604bd53352c3fb 203 Gene3D G3DSA:3.40.50.150 7 190 1.1E-28 T 28-03-2018 CIG75_RS03150 500a5b7ccfb0dbf34808c407605bd609 150 Gene3D G3DSA:3.10.450.40 23 149 1.5E-12 T 28-03-2018 CIG75_RS03150 500a5b7ccfb0dbf34808c407605bd609 150 SUPERFAMILY SSF160719 48 116 4.58E-6 T 28-03-2018 CIG75_RS03150 500a5b7ccfb0dbf34808c407605bd609 150 ProDom PD033094 XKDS PHAGE-LIKE PBSX ELEMENT PHAGE LIN1286 RELATED YQBS 44 140 3.0E-10 T 28-03-2018 IPR020288 Protein of unknown function DUF2634 CIG75_RS03150 500a5b7ccfb0dbf34808c407605bd609 150 Pfam PF10934 Protein of unknown function (DUF2634) 32 133 2.9E-28 T 28-03-2018 IPR020288 Protein of unknown function DUF2634 CIG75_RS10075 d76f4e7544d5f6205fa3bc549712c9a7 239 SMART SM00382 28 219 0.0022 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS10075 d76f4e7544d5f6205fa3bc549712c9a7 239 SUPERFAMILY SSF52540 7 226 1.07E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS10075 d76f4e7544d5f6205fa3bc549712c9a7 239 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS10075 d76f4e7544d5f6205fa3bc549712c9a7 239 Gene3D G3DSA:3.40.50.300 3 235 1.7E-44 T 28-03-2018 CIG75_RS10075 d76f4e7544d5f6205fa3bc549712c9a7 239 Pfam PF00005 ABC transporter 20 171 5.1E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS03470 7070d8c7c6ef202b9c54475847a133b0 320 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 299 4.2E-17 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CIG75_RS03470 7070d8c7c6ef202b9c54475847a133b0 320 Gene3D G3DSA:3.40.50.300 1 320 1.3E-85 T 28-03-2018 CIG75_RS03470 7070d8c7c6ef202b9c54475847a133b0 320 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 233 319 4.1E-28 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CIG75_RS03470 7070d8c7c6ef202b9c54475847a133b0 320 SUPERFAMILY SSF52540 4 254 4.51E-77 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS03470 7070d8c7c6ef202b9c54475847a133b0 320 Pfam PF00005 ABC transporter 32 182 5.1E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS03470 7070d8c7c6ef202b9c54475847a133b0 320 SMART SM00382 40 232 4.0E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS03470 7070d8c7c6ef202b9c54475847a133b0 320 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS09200 2e4ca87f735b7c68b9c0a7a2d6946372 409 Gene3D G3DSA:3.90.1170.30 28 100 9.2E-6 T 28-03-2018 CIG75_RS09200 2e4ca87f735b7c68b9c0a7a2d6946372 409 Gene3D G3DSA:1.10.287.620 101 233 2.5E-7 T 28-03-2018 CIG75_RS09200 2e4ca87f735b7c68b9c0a7a2d6946372 409 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 175 402 1.2E-36 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 CIG75_RS09200 2e4ca87f735b7c68b9c0a7a2d6946372 409 SUPERFAMILY SSF111369 161 326 7.19E-9 T 28-03-2018 CIG75_RS09200 2e4ca87f735b7c68b9c0a7a2d6946372 409 SUPERFAMILY SSF111369 52 129 5.75E-8 T 28-03-2018 CIG75_RS09200 2e4ca87f735b7c68b9c0a7a2d6946372 409 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 50 321 1.4E-20 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CIG75_RS09215 c6a6f02083dcd633de3ca3e8c7e3ebe1 436 SUPERFAMILY SSF48179 201 295 9.86E-31 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CIG75_RS09215 c6a6f02083dcd633de3ca3e8c7e3ebe1 436 SUPERFAMILY SSF51735 1 195 3.43E-56 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS09215 c6a6f02083dcd633de3ca3e8c7e3ebe1 436 Gene3D G3DSA:1.20.5.100 202 224 2.3E-16 T 28-03-2018 CIG75_RS09215 c6a6f02083dcd633de3ca3e8c7e3ebe1 436 SUPERFAMILY SSF52413 305 427 6.8E-35 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CIG75_RS09215 c6a6f02083dcd633de3ca3e8c7e3ebe1 436 PIRSF PIRSF000124 1 432 1.5E-141 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CIG75_RS09215 c6a6f02083dcd633de3ca3e8c7e3ebe1 436 Gene3D G3DSA:3.40.50.720 225 428 2.0E-71 T 28-03-2018 CIG75_RS09215 c6a6f02083dcd633de3ca3e8c7e3ebe1 436 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 413 6.4E-135 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CIG75_RS09215 c6a6f02083dcd633de3ca3e8c7e3ebe1 436 Gene3D G3DSA:3.40.50.720 1 201 1.1E-56 T 28-03-2018 CIG75_RS09215 c6a6f02083dcd633de3ca3e8c7e3ebe1 436 PIRSF PIRSF500134 1 435 4.2E-168 T 28-03-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 CIG75_RS09215 c6a6f02083dcd633de3ca3e8c7e3ebe1 436 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 186 9.0E-64 T 28-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CIG75_RS09215 c6a6f02083dcd633de3ca3e8c7e3ebe1 436 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 316 416 1.7E-28 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CIG75_RS09215 c6a6f02083dcd633de3ca3e8c7e3ebe1 436 SMART SM00984 316 417 2.8E-42 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CIG75_RS09215 c6a6f02083dcd633de3ca3e8c7e3ebe1 436 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 202 293 5.3E-38 T 28-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CIG75_RS02720 98f5bb7329856560d41edf26c80fe2fa 1016 SUPERFAMILY SSF82714 689 773 3.92E-6 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CIG75_RS02720 98f5bb7329856560d41edf26c80fe2fa 1016 SUPERFAMILY SSF82866 286 483 1.01E-40 T 28-03-2018 CIG75_RS02720 98f5bb7329856560d41edf26c80fe2fa 1016 Pfam PF00873 AcrB/AcrD/AcrF family 4 993 2.1E-199 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CIG75_RS02720 98f5bb7329856560d41edf26c80fe2fa 1016 SUPERFAMILY SSF82714 184 261 1.57E-10 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CIG75_RS02720 98f5bb7329856560d41edf26c80fe2fa 1016 SUPERFAMILY SSF82866 778 998 4.19E-48 T 28-03-2018 CIG75_RS02720 98f5bb7329856560d41edf26c80fe2fa 1016 SUPERFAMILY SSF82693 43 131 9.42E-16 T 28-03-2018 CIG75_RS02720 98f5bb7329856560d41edf26c80fe2fa 1016 Gene3D G3DSA:1.20.1640.10 263 485 1.3E-46 T 28-03-2018 CIG75_RS02720 98f5bb7329856560d41edf26c80fe2fa 1016 Gene3D G3DSA:1.20.1640.10 781 997 8.1E-40 T 28-03-2018 CIG75_RS02720 98f5bb7329856560d41edf26c80fe2fa 1016 PRINTS PR00702 Acriflavin resistance protein family signature 39 57 8.1E-42 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CIG75_RS02720 98f5bb7329856560d41edf26c80fe2fa 1016 PRINTS PR00702 Acriflavin resistance protein family signature 349 370 8.1E-42 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CIG75_RS02720 98f5bb7329856560d41edf26c80fe2fa 1016 PRINTS PR00702 Acriflavin resistance protein family signature 322 345 8.1E-42 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CIG75_RS02720 98f5bb7329856560d41edf26c80fe2fa 1016 PRINTS PR00702 Acriflavin resistance protein family signature 377 401 8.1E-42 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CIG75_RS02720 98f5bb7329856560d41edf26c80fe2fa 1016 PRINTS PR00702 Acriflavin resistance protein family signature 11 35 8.1E-42 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CIG75_RS02720 98f5bb7329856560d41edf26c80fe2fa 1016 PRINTS PR00702 Acriflavin resistance protein family signature 455 478 8.1E-42 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CIG75_RS02720 98f5bb7329856560d41edf26c80fe2fa 1016 PRINTS PR00702 Acriflavin resistance protein family signature 430 453 8.1E-42 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CIG75_RS02720 98f5bb7329856560d41edf26c80fe2fa 1016 SUPERFAMILY SSF82693 142 181 9.94E-11 T 28-03-2018 CIG75_RS02720 98f5bb7329856560d41edf26c80fe2fa 1016 SUPERFAMILY SSF82693 264 306 9.94E-11 T 28-03-2018 CIG75_RS02720 98f5bb7329856560d41edf26c80fe2fa 1016 Gene3D G3DSA:3.30.70.1430 41 140 9.2E-20 T 28-03-2018 CIG75_RS02720 98f5bb7329856560d41edf26c80fe2fa 1016 Gene3D G3DSA:3.30.2090.10 195 262 3.5E-13 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CIG75_RS02720 98f5bb7329856560d41edf26c80fe2fa 1016 Gene3D G3DSA:3.30.70.100 158 194 0.26 T 28-03-2018 CIG75_RS02720 98f5bb7329856560d41edf26c80fe2fa 1016 Gene3D G3DSA:3.30.2090.10 702 775 9.5E-10 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CIG75_RS02720 98f5bb7329856560d41edf26c80fe2fa 1016 Gene3D G3DSA:3.30.70.1430 542 701 4.9E-4 T 28-03-2018 CIG75_RS01510 3ea2141e9caeee3e0f87c69e7e29f41d 510 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 434 450 2.6E-27 T 28-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 CIG75_RS01510 3ea2141e9caeee3e0f87c69e7e29f41d 510 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 314 334 2.6E-27 T 28-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 CIG75_RS01510 3ea2141e9caeee3e0f87c69e7e29f41d 510 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 371 382 2.6E-27 T 28-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 CIG75_RS01510 3ea2141e9caeee3e0f87c69e7e29f41d 510 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 350 366 2.6E-27 T 28-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 CIG75_RS01510 3ea2141e9caeee3e0f87c69e7e29f41d 510 SUPERFAMILY SSF55486 213 510 1.25E-94 T 28-03-2018 CIG75_RS01510 3ea2141e9caeee3e0f87c69e7e29f41d 510 Gene3D G3DSA:3.10.170.10 213 363 2.3E-47 T 28-03-2018 CIG75_RS01510 3ea2141e9caeee3e0f87c69e7e29f41d 510 Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif 78 126 1.3E-13 T 28-03-2018 IPR011096 FTP domain CIG75_RS01510 3ea2141e9caeee3e0f87c69e7e29f41d 510 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 215 359 1.5E-46 T 28-03-2018 IPR013856 Peptidase M4 domain GO:0004222 CIG75_RS01510 3ea2141e9caeee3e0f87c69e7e29f41d 510 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 362 510 3.7E-45 T 28-03-2018 IPR001570 Peptidase M4, C-terminal GO:0004222 CIG75_RS01510 3ea2141e9caeee3e0f87c69e7e29f41d 510 Gene3D G3DSA:1.10.390.10 364 510 3.0E-50 T 28-03-2018 CIG75_RS01975 b4b8ebedb73b725a153b2dcbf6e926e1 330 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 218 231 - T 28-03-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CIG75_RS01975 b4b8ebedb73b725a153b2dcbf6e926e1 330 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 13 330 25.636 T 28-03-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CIG75_RS01975 b4b8ebedb73b725a153b2dcbf6e926e1 330 Pfam PF00146 NADH dehydrogenase 22 324 3.8E-125 T 28-03-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CIG75_RS00435 d215905bfc80dce4e9e2c193c1c15df0 133 Gene3D G3DSA:3.10.180.10 1 133 2.2E-22 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CIG75_RS00435 d215905bfc80dce4e9e2c193c1c15df0 133 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 3 128 6.8E-14 T 28-03-2018 IPR028973 PhnB-like CIG75_RS00435 d215905bfc80dce4e9e2c193c1c15df0 133 SUPERFAMILY SSF54593 1 132 1.02E-31 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CIG75_RS08910 f8db7bcd54e8eef079bd3a4b43867a43 70 SUPERFAMILY SSF47413 4 66 4.29E-18 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CIG75_RS08910 f8db7bcd54e8eef079bd3a4b43867a43 70 Gene3D G3DSA:1.10.10.60 46 68 0.084 T 28-03-2018 CIG75_RS08910 f8db7bcd54e8eef079bd3a4b43867a43 70 Pfam PF01381 Helix-turn-helix 10 64 8.0E-16 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS08910 f8db7bcd54e8eef079bd3a4b43867a43 70 SMART SM00530 9 64 7.1E-16 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS08910 f8db7bcd54e8eef079bd3a4b43867a43 70 Gene3D G3DSA:1.10.260.40 2 45 8.5E-16 T 28-03-2018 CIG75_RS09380 6615b3db0d8e516ac0008b3e5f78ce99 296 Pfam PF14045 YIEGIA protein 7 287 6.5E-119 T 28-03-2018 IPR025918 YIEGIA protein CIG75_RS09380 6615b3db0d8e516ac0008b3e5f78ce99 296 ProDom PD128584 YPHB BH1976 TRANSMEMBRANE MEMBRANE SEAA 1 280 3.0E-93 T 28-03-2018 CIG75_RS13750 54d1b95f19539ab20ca94bbbadf81bf0 64 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 6 60 6.5E-21 T 28-03-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 CIG75_RS13750 54d1b95f19539ab20ca94bbbadf81bf0 64 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 21 30 - T 28-03-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 CIG75_RS02845 abe2a8807491780c1b58a4262ddffb27 219 SUPERFAMILY SSF55811 4 159 1.19E-25 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CIG75_RS02845 abe2a8807491780c1b58a4262ddffb27 219 Pfam PF00293 NUDIX domain 41 128 1.9E-8 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CIG75_RS02845 abe2a8807491780c1b58a4262ddffb27 219 Gene3D G3DSA:3.90.79.10 1 166 8.8E-19 T 28-03-2018 CIG75_RS14785 4fd409f037e661678cb0ac4013019956 252 Hamap MF_00114 Deoxyribose-phosphate aldolase [deoC]. 32 247 35.538 T 28-03-2018 IPR028581 Deoxyribose-phosphate aldolase type I GO:0004139 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180 CIG75_RS14785 4fd409f037e661678cb0ac4013019956 252 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 34 242 4.5E-87 T 28-03-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CIG75_RS14785 4fd409f037e661678cb0ac4013019956 252 Pfam PF01791 DeoC/LacD family aldolase 45 241 1.6E-19 T 28-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CIG75_RS14785 4fd409f037e661678cb0ac4013019956 252 SMART SM01133 33 245 2.8E-90 T 28-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CIG75_RS14785 4fd409f037e661678cb0ac4013019956 252 PIRSF PIRSF001357 28 251 7.9E-75 T 28-03-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CIG75_RS14785 4fd409f037e661678cb0ac4013019956 252 Gene3D G3DSA:3.20.20.70 12 248 3.5E-91 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CIG75_RS14785 4fd409f037e661678cb0ac4013019956 252 SUPERFAMILY SSF51569 32 245 1.78E-79 T 28-03-2018 CIG75_RS15210 a9cd227ae7ebae1cd885e47052fcaf24 377 Pfam PF14031 Putative serine dehydratase domain 264 358 2.1E-22 T 28-03-2018 IPR026956 D-serine dehydratase-like domain CIG75_RS15210 a9cd227ae7ebae1cd885e47052fcaf24 377 SMART SM01119 264 360 3.6E-35 T 28-03-2018 IPR026956 D-serine dehydratase-like domain CIG75_RS15210 a9cd227ae7ebae1cd885e47052fcaf24 377 Gene3D G3DSA:3.20.20.10 8 254 1.5E-44 T 28-03-2018 IPR029066 PLP-binding barrel CIG75_RS15210 a9cd227ae7ebae1cd885e47052fcaf24 377 Pfam PF01168 Alanine racemase, N-terminal domain 21 248 1.1E-27 T 28-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CIG75_RS15210 a9cd227ae7ebae1cd885e47052fcaf24 377 SUPERFAMILY SSF51419 21 255 6.25E-35 T 28-03-2018 IPR029066 PLP-binding barrel CIG75_RS09735 4a08f4aad3f044227b8b110ad006a7d3 310 Pfam PF00849 RNA pseudouridylate synthase 89 240 7.4E-28 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CIG75_RS09735 4a08f4aad3f044227b8b110ad006a7d3 310 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 14 299 4.3E-77 T 28-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 CIG75_RS09735 4a08f4aad3f044227b8b110ad006a7d3 310 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 132 146 - T 28-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 CIG75_RS09735 4a08f4aad3f044227b8b110ad006a7d3 310 Gene3D G3DSA:3.30.2350.10 82 302 1.9E-65 T 28-03-2018 CIG75_RS09735 4a08f4aad3f044227b8b110ad006a7d3 310 Gene3D G3DSA:3.10.290.10 2 73 7.6E-7 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CIG75_RS09735 4a08f4aad3f044227b8b110ad006a7d3 310 SUPERFAMILY SSF55120 74 299 4.32E-71 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CIG75_RS11525 e2c5c32c59caf196fd3a2331c47fc7fa 267 TIGRFAM TIGR02170 thyX: thymidylate synthase, flavin-dependent 34 221 8.3E-29 T 28-03-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 CIG75_RS11525 e2c5c32c59caf196fd3a2331c47fc7fa 267 SUPERFAMILY SSF69796 34 227 6.41E-34 T 28-03-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 CIG75_RS11525 e2c5c32c59caf196fd3a2331c47fc7fa 267 Pfam PF02511 Thymidylate synthase complementing protein 29 216 7.8E-34 T 28-03-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 CIG75_RS10170 2a2cfee2178a61e13ab69024a7803894 165 Gene3D G3DSA:1.10.260.40 15 164 3.6E-9 T 28-03-2018 CIG75_RS10170 2a2cfee2178a61e13ab69024a7803894 165 Pfam PF01381 Helix-turn-helix 22 65 1.0E-5 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS10170 2a2cfee2178a61e13ab69024a7803894 165 SUPERFAMILY SSF47413 15 59 2.12E-8 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CIG75_RS17990 4a4963f0e6224c400640fd7a71166d40 265 Pfam PF06182 ABC-2 family transporter protein 36 263 1.4E-15 T 28-03-2018 IPR010390 Protein of unknown function DUF990 CIG75_RS18570 2327291a2c5194596fa99113dacb1c7e 190 SUPERFAMILY SSF46689 3 68 2.28E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CIG75_RS18570 2327291a2c5194596fa99113dacb1c7e 190 Gene3D G3DSA:1.10.10.60 1 45 6.2E-11 T 28-03-2018 CIG75_RS18570 2327291a2c5194596fa99113dacb1c7e 190 Gene3D G3DSA:1.10.10.60 46 182 7.7E-7 T 28-03-2018 CIG75_RS18570 2327291a2c5194596fa99113dacb1c7e 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 55 6.5E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CIG75_RS10970 a4490b9433599f29d63f4c771fff2e03 388 Pfam PF00899 ThiF family 127 338 4.4E-18 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CIG75_RS10970 a4490b9433599f29d63f4c771fff2e03 388 SUPERFAMILY SSF69572 127 377 9.03E-25 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CIG75_RS10970 a4490b9433599f29d63f4c771fff2e03 388 TIGRFAM TIGR03882 cyclo_dehyd_2: bacteriocin biosynthesis cyclodehydratase domain 253 381 9.3E-14 T 28-03-2018 IPR022291 Bacteriocin biosynthesis, cyclodehydratase domain CIG75_RS10970 a4490b9433599f29d63f4c771fff2e03 388 Gene3D G3DSA:3.40.50.720 123 378 3.1E-32 T 28-03-2018 CIG75_RS07960 ad9b6337412b85b9f4dc43b11755da43 347 SUPERFAMILY SSF56112 18 333 1.9E-50 T 28-03-2018 IPR011009 Protein kinase-like domain CIG75_RS07960 ad9b6337412b85b9f4dc43b11755da43 347 Pfam PF01636 Phosphotransferase enzyme family 36 251 1.1E-19 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CIG75_RS07960 ad9b6337412b85b9f4dc43b11755da43 347 Gene3D G3DSA:3.30.200.20 2 101 2.6E-17 T 28-03-2018 CIG75_RS07960 ad9b6337412b85b9f4dc43b11755da43 347 Gene3D G3DSA:3.90.1200.10 102 334 4.9E-27 T 28-03-2018 CIG75_RS07960 ad9b6337412b85b9f4dc43b11755da43 347 TIGRFAM TIGR02906 spore_CotS: spore coat protein, CotS family 26 333 5.4E-71 T 28-03-2018 IPR014255 Spore coat protein CotS CIG75_RS15850 6cce1a64270cf381bef49ae03f951ecd 212 Pfam PF09335 SNARE associated Golgi protein 26 152 2.1E-18 T 28-03-2018 IPR032816 SNARE associated Golgi protein CIG75_RS13625 fcb2d8a669bfb361f2e31095ff3ed41c 150 SUPERFAMILY SSF50475 9 90 1.32E-9 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CIG75_RS13625 fcb2d8a669bfb361f2e31095ff3ed41c 150 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 10 89 1.1E-5 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CIG75_RS13625 fcb2d8a669bfb361f2e31095ff3ed41c 150 Gene3D G3DSA:2.30.110.10 1 150 3.1E-18 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CIG75_RS19680 bae7b5ecb4b36c63ef428e095b13da99 109 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 43 106 4.0E-30 T 28-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS19680 bae7b5ecb4b36c63ef428e095b13da99 109 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 6 107 7.2E-41 T 28-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS19680 bae7b5ecb4b36c63ef428e095b13da99 109 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 6 101 22.876 T 28-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS19680 bae7b5ecb4b36c63ef428e095b13da99 109 SMART SM00739 7 34 1.3E-5 T 28-03-2018 IPR005824 KOW CIG75_RS19680 bae7b5ecb4b36c63ef428e095b13da99 109 Pfam PF00467 KOW motif 10 41 1.4E-7 T 28-03-2018 IPR005824 KOW CIG75_RS19680 bae7b5ecb4b36c63ef428e095b13da99 109 Gene3D G3DSA:2.30.30.30 2 105 3.6E-37 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 CIG75_RS19680 bae7b5ecb4b36c63ef428e095b13da99 109 SUPERFAMILY SSF50104 4 105 4.14E-37 T 28-03-2018 IPR008991 Translation protein SH3-like domain CIG75_RS19680 bae7b5ecb4b36c63ef428e095b13da99 109 ProSitePatterns PS01108 Ribosomal protein L24 signature. 11 28 - T 28-03-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS00075 f1b5639888c4c35da422f156dad81f0e 605 SMART SM00382 37 184 1.4E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS00075 f1b5639888c4c35da422f156dad81f0e 605 Gene3D G3DSA:1.20.272.10 243 364 3.6E-18 T 28-03-2018 CIG75_RS00075 f1b5639888c4c35da422f156dad81f0e 605 Gene3D G3DSA:1.10.8.60 167 242 4.5E-18 T 28-03-2018 CIG75_RS00075 f1b5639888c4c35da422f156dad81f0e 605 SUPERFAMILY SSF48019 244 363 4.59E-21 T 28-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CIG75_RS00075 f1b5639888c4c35da422f156dad81f0e 605 Pfam PF13177 DNA polymerase III, delta subunit 20 178 4.9E-47 T 28-03-2018 CIG75_RS00075 f1b5639888c4c35da422f156dad81f0e 605 SUPERFAMILY SSF52540 32 220 1.5E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS00075 f1b5639888c4c35da422f156dad81f0e 605 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 3 358 2.2E-139 T 28-03-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 CIG75_RS00075 f1b5639888c4c35da422f156dad81f0e 605 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 124 142 1.2E-5 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CIG75_RS00075 f1b5639888c4c35da422f156dad81f0e 605 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 41 59 1.2E-5 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CIG75_RS00075 f1b5639888c4c35da422f156dad81f0e 605 Gene3D G3DSA:3.40.50.300 2 166 3.8E-41 T 28-03-2018 CIG75_RS00075 f1b5639888c4c35da422f156dad81f0e 605 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 232 371 1.2E-13 T 28-03-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 CIG75_RS03360 02b79d278da516c7aae37f51ee26aaf8 404 Gene3D G3DSA:3.90.1150.10 302 402 2.1E-26 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CIG75_RS03360 02b79d278da516c7aae37f51ee26aaf8 404 Pfam PF00155 Aminotransferase class I and II 44 394 2.0E-38 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CIG75_RS03360 02b79d278da516c7aae37f51ee26aaf8 404 Gene3D G3DSA:3.40.640.10 52 301 1.8E-49 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CIG75_RS03360 02b79d278da516c7aae37f51ee26aaf8 404 SUPERFAMILY SSF53383 9 399 1.02E-95 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CIG75_RS03490 13438c70ee9c488e49a2c1ad8f4aff5b 299 Gene3D G3DSA:1.10.3720.10 25 287 5.1E-45 T 28-03-2018 CIG75_RS03490 13438c70ee9c488e49a2c1ad8f4aff5b 299 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 298 1.2E-32 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CIG75_RS03490 13438c70ee9c488e49a2c1ad8f4aff5b 299 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 21 73 6.0E-16 T 28-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CIG75_RS03490 13438c70ee9c488e49a2c1ad8f4aff5b 299 SUPERFAMILY SSF161098 91 279 3.27E-32 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CIG75_RS08535 7e8eda65bff971d19f4c5bc29d3ad755 204 SUPERFAMILY SSF55811 28 197 5.82E-54 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CIG75_RS08535 7e8eda65bff971d19f4c5bc29d3ad755 204 Pfam PF00293 NUDIX domain 64 178 4.1E-17 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CIG75_RS08535 7e8eda65bff971d19f4c5bc29d3ad755 204 Gene3D G3DSA:3.90.79.10 17 204 2.2E-45 T 28-03-2018 CIG75_RS09965 bd8717a3b66e27f9ea71a10fea9a3ddc 432 Pfam PF01979 Amidohydrolase family 58 404 3.2E-79 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CIG75_RS09965 bd8717a3b66e27f9ea71a10fea9a3ddc 432 SUPERFAMILY SSF51556 60 355 2.83E-105 T 28-03-2018 IPR032466 Metal-dependent hydrolase CIG75_RS09965 bd8717a3b66e27f9ea71a10fea9a3ddc 432 SUPERFAMILY SSF51338 355 430 1.78E-33 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CIG75_RS09965 bd8717a3b66e27f9ea71a10fea9a3ddc 432 SUPERFAMILY SSF51338 4 60 1.78E-33 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CIG75_RS09965 bd8717a3b66e27f9ea71a10fea9a3ddc 432 Gene3D G3DSA:3.20.20.140 75 355 6.3E-67 T 28-03-2018 CIG75_RS09965 bd8717a3b66e27f9ea71a10fea9a3ddc 432 Gene3D G3DSA:2.30.40.10 3 74 2.0E-15 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CIG75_RS09965 bd8717a3b66e27f9ea71a10fea9a3ddc 432 Hamap MF_01281 5'-deoxyadenosine deaminase [dadD]. 3 430 48.407 T 28-03-2018 IPR023512 Deaminase MtaD/DadD GO:0019239 CIG75_RS06790 f40a45f7acafb83e8a3d6b580ff912d0 264 TIGRFAM TIGR02832 spo_yunB: sporulation protein YunB 33 231 1.9E-53 T 28-03-2018 IPR014197 Sporulation protein YunB CIG75_RS06790 f40a45f7acafb83e8a3d6b580ff912d0 264 Pfam PF09560 Sporulation protein YunB (Spo_YunB) 140 229 2.3E-28 T 28-03-2018 IPR014197 Sporulation protein YunB CIG75_RS06790 f40a45f7acafb83e8a3d6b580ff912d0 264 PIRSF PIRSF021383 22 256 1.0E-47 T 28-03-2018 IPR014197 Sporulation protein YunB CIG75_RS13880 0dce30f734818767096c3bd38aa9bc55 333 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 69 79 1.1E-17 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CIG75_RS13880 0dce30f734818767096c3bd38aa9bc55 333 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 12 34 1.1E-17 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CIG75_RS13880 0dce30f734818767096c3bd38aa9bc55 333 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 155 179 1.1E-17 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CIG75_RS13880 0dce30f734818767096c3bd38aa9bc55 333 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 116 124 1.1E-17 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CIG75_RS13880 0dce30f734818767096c3bd38aa9bc55 333 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 206 222 1.1E-17 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CIG75_RS13880 0dce30f734818767096c3bd38aa9bc55 333 Hamap MF_01685 Ferredoxin--NADP reductase. 10 331 42.411 T 28-03-2018 IPR022890 Ferredoxin--NADP reductase, type 2 GO:0004324|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 CIG75_RS13880 0dce30f734818767096c3bd38aa9bc55 333 Gene3D G3DSA:3.40.50.720 152 325 7.5E-21 T 28-03-2018 CIG75_RS13880 0dce30f734818767096c3bd38aa9bc55 333 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 159 177 1.3E-18 T 28-03-2018 CIG75_RS13880 0dce30f734818767096c3bd38aa9bc55 333 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 13 32 1.3E-18 T 28-03-2018 CIG75_RS13880 0dce30f734818767096c3bd38aa9bc55 333 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 268 290 1.3E-18 T 28-03-2018 CIG75_RS13880 0dce30f734818767096c3bd38aa9bc55 333 SUPERFAMILY SSF51905 11 312 2.79E-37 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS13880 0dce30f734818767096c3bd38aa9bc55 333 Gene3D G3DSA:3.50.50.60 4 148 3.8E-16 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS13880 0dce30f734818767096c3bd38aa9bc55 333 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 11 295 2.7E-31 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS01545 7a5eab868c13f758ad123702c2c81bfb 342 SUPERFAMILY SSF52540 108 201 8.59E-5 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS01545 7a5eab868c13f758ad123702c2c81bfb 342 SUPERFAMILY SSF52540 7 65 8.59E-5 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS01545 7a5eab868c13f758ad123702c2c81bfb 342 Gene3D G3DSA:3.40.50.300 3 249 9.2E-8 T 28-03-2018 CIG75_RS02295 aff566b7c90208960cf7aaa80f8b6313 116 Gene3D G3DSA:3.10.450.40 42 114 7.8E-4 T 28-03-2018 CIG75_RS03715 0e666b575ec1859137ecd3f4973094c2 104 Hamap MF_00338 UPF0145 protein YbjQ [ybjQ]. 1 103 23.912 T 28-03-2018 IPR002765 Uncharacterised protein family UPF0145 CIG75_RS03715 0e666b575ec1859137ecd3f4973094c2 104 Gene3D G3DSA:3.30.110.70 1 103 3.1E-35 T 28-03-2018 IPR035439 Uncharacterised protein family UPF0145/C2CD5 Reactome: R-HSA-1445148 CIG75_RS03715 0e666b575ec1859137ecd3f4973094c2 104 Pfam PF01906 Putative heavy-metal-binding 1 102 3.4E-38 T 28-03-2018 IPR002765 Uncharacterised protein family UPF0145 CIG75_RS03715 0e666b575ec1859137ecd3f4973094c2 104 SUPERFAMILY SSF117782 1 103 1.31E-37 T 28-03-2018 IPR002765 Uncharacterised protein family UPF0145 CIG75_RS16585 cc0e348e2359828be811924d01d03478 202 SUPERFAMILY SSF46609 1 91 4.19E-37 T 28-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CIG75_RS16585 cc0e348e2359828be811924d01d03478 202 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 2 90 2.2E-31 T 28-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CIG75_RS16585 cc0e348e2359828be811924d01d03478 202 Gene3D G3DSA:1.10.287.990 20 90 1.0E-31 T 28-03-2018 CIG75_RS16585 cc0e348e2359828be811924d01d03478 202 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 97 197 1.6E-40 T 28-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CIG75_RS16585 cc0e348e2359828be811924d01d03478 202 PRINTS PR01703 Manganese superoxide dismutase signature 126 134 1.0E-25 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CIG75_RS16585 cc0e348e2359828be811924d01d03478 202 PRINTS PR01703 Manganese superoxide dismutase signature 162 174 1.0E-25 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CIG75_RS16585 cc0e348e2359828be811924d01d03478 202 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 1.0E-25 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CIG75_RS16585 cc0e348e2359828be811924d01d03478 202 PRINTS PR01703 Manganese superoxide dismutase signature 73 86 1.0E-25 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CIG75_RS16585 cc0e348e2359828be811924d01d03478 202 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 1.0E-25 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CIG75_RS16585 cc0e348e2359828be811924d01d03478 202 PIRSF PIRSF000349 1 202 1.0E-81 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CIG75_RS16585 cc0e348e2359828be811924d01d03478 202 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 164 171 - T 28-03-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CIG75_RS16585 cc0e348e2359828be811924d01d03478 202 SUPERFAMILY SSF54719 92 201 4.98E-45 T 28-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CIG75_RS00160 80c761cc102a5b5df27f9f7a7427b8f1 344 Pfam PF14175 YaaC-like Protein 21 327 2.5E-63 T 28-03-2018 IPR026988 YaaC-like protein CIG75_RS15290 9f02eec959a80559938f3d18fc780812 332 Gene3D G3DSA:3.90.1200.10 92 324 1.8E-30 T 28-03-2018 CIG75_RS15290 9f02eec959a80559938f3d18fc780812 332 Pfam PF01636 Phosphotransferase enzyme family 24 260 5.2E-11 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CIG75_RS15290 9f02eec959a80559938f3d18fc780812 332 SUPERFAMILY SSF56112 4 297 2.85E-37 T 28-03-2018 IPR011009 Protein kinase-like domain CIG75_RS15290 9f02eec959a80559938f3d18fc780812 332 Gene3D G3DSA:3.30.200.20 2 91 9.8E-11 T 28-03-2018 CIG75_RS15290 9f02eec959a80559938f3d18fc780812 332 TIGRFAM TIGR02906 spore_CotS: spore coat protein, CotS family 15 322 1.5E-53 T 28-03-2018 IPR014255 Spore coat protein CotS CIG75_RS09825 d4a1c4d17b097c0ca36eee1e2abade97 166 PRINTS PR01438 Universal stress protein signature 21 39 6.8E-20 T 28-03-2018 IPR006015 Universal stress protein A CIG75_RS09825 d4a1c4d17b097c0ca36eee1e2abade97 166 PRINTS PR01438 Universal stress protein signature 144 166 6.8E-20 T 28-03-2018 IPR006015 Universal stress protein A CIG75_RS09825 d4a1c4d17b097c0ca36eee1e2abade97 166 PRINTS PR01438 Universal stress protein signature 126 138 6.8E-20 T 28-03-2018 IPR006015 Universal stress protein A CIG75_RS09825 d4a1c4d17b097c0ca36eee1e2abade97 166 Pfam PF00582 Universal stress protein family 20 166 1.0E-28 T 28-03-2018 IPR006016 UspA GO:0006950 CIG75_RS09825 d4a1c4d17b097c0ca36eee1e2abade97 166 SUPERFAMILY SSF52402 21 166 4.94E-29 T 28-03-2018 CIG75_RS09825 d4a1c4d17b097c0ca36eee1e2abade97 166 Gene3D G3DSA:3.40.50.620 2 166 4.5E-30 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CIG75_RS16615 7dcb05956ce3abdbba1e1a3c65a7956d 87 Pfam PF05768 Glutaredoxin-like domain (DUF836) 5 69 2.1E-16 T 28-03-2018 IPR008554 Glutaredoxin-like CIG75_RS16615 7dcb05956ce3abdbba1e1a3c65a7956d 87 SUPERFAMILY SSF52833 2 80 9.01E-18 T 28-03-2018 IPR012336 Thioredoxin-like fold CIG75_RS16615 7dcb05956ce3abdbba1e1a3c65a7956d 87 Gene3D G3DSA:3.40.30.10 4 87 4.0E-12 T 28-03-2018 CIG75_RS11595 aff4a5e9f7fbf749136f808cf8b9e24f 192 Pfam PF01066 CDP-alcohol phosphatidyltransferase 4 83 2.2E-15 T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CIG75_RS11595 aff4a5e9f7fbf749136f808cf8b9e24f 192 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 3 190 5.6E-50 T 28-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 CIG75_RS11595 aff4a5e9f7fbf749136f808cf8b9e24f 192 PIRSF PIRSF000847 1 192 7.3E-48 T 28-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 CIG75_RS11595 aff4a5e9f7fbf749136f808cf8b9e24f 192 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 61 83 - T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CIG75_RS02365 5631e3519a52b213c65cad5b557903c8 134 Hamap MF_01185 Flagellar assembly factor FliW [fliW]. 11 133 18.52 T 28-03-2018 IPR003775 Flagellar assembly factor FliW GO:0044780 CIG75_RS02365 5631e3519a52b213c65cad5b557903c8 134 SUPERFAMILY SSF141457 11 131 9.29E-27 T 28-03-2018 IPR024046 Flagellar assembly factor FliW domain CIG75_RS02365 5631e3519a52b213c65cad5b557903c8 134 Pfam PF02623 FliW protein 14 130 2.0E-27 T 28-03-2018 IPR003775 Flagellar assembly factor FliW GO:0044780 CIG75_RS02365 5631e3519a52b213c65cad5b557903c8 134 Gene3D G3DSA:2.30.290.10 2 134 4.4E-29 T 28-03-2018 IPR024046 Flagellar assembly factor FliW domain CIG75_RS07505 c1ff0eac36e6d00043d5a88e0a717436 263 SUPERFAMILY SSF53448 27 215 3.52E-10 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CIG75_RS07505 c1ff0eac36e6d00043d5a88e0a717436 263 Gene3D G3DSA:3.90.550.10 2 256 6.9E-8 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CIG75_RS15790 548d48dcd7087327890c35ec7b6d7936 197 Pfam PF13798 Protein of unknown function with PCYCGC motif 70 196 3.7E-54 T 28-03-2018 IPR025673 Protein of unknown function with PCYCGC motif CIG75_RS11120 b56abe9ef60a586514bb09df733c3659 418 Pfam PF14907 Uncharacterised nucleotidyltransferase 56 265 1.5E-21 T 28-03-2018 CIG75_RS11120 b56abe9ef60a586514bb09df733c3659 418 SUPERFAMILY SSF81301 72 210 7.52E-8 T 28-03-2018 CIG75_RS07340 184e9f466a3c1f487a09e9395121f51f 146 PIRSF PIRSF001467 1 146 1.3E-38 T 28-03-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 CIG75_RS07340 184e9f466a3c1f487a09e9395121f51f 146 Gene3D G3DSA:2.40.100.10 1 146 5.0E-49 T 28-03-2018 IPR029000 Cyclophilin-like domain CIG75_RS07340 184e9f466a3c1f487a09e9395121f51f 146 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 44 56 1.9E-22 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CIG75_RS07340 184e9f466a3c1f487a09e9395121f51f 146 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 84 99 1.9E-22 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CIG75_RS07340 184e9f466a3c1f487a09e9395121f51f 146 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 114 129 1.9E-22 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CIG75_RS07340 184e9f466a3c1f487a09e9395121f51f 146 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 18 33 1.9E-22 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CIG75_RS07340 184e9f466a3c1f487a09e9395121f51f 146 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 39 56 - T 28-03-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 CIG75_RS07340 184e9f466a3c1f487a09e9395121f51f 146 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 7 145 3.8E-40 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CIG75_RS07340 184e9f466a3c1f487a09e9395121f51f 146 SUPERFAMILY SSF50891 4 139 6.14E-45 T 28-03-2018 IPR029000 Cyclophilin-like domain CIG75_RS04280 bbe335a8eebf203d0a4809f417d0428c 118 SUPERFAMILY SSF46458 2 114 1.28E-36 T 28-03-2018 IPR009050 Globin-like CIG75_RS04280 bbe335a8eebf203d0a4809f417d0428c 118 Pfam PF01152 Bacterial-like globin 2 113 3.1E-31 T 28-03-2018 IPR001486 Truncated hemoglobin GO:0019825 CIG75_RS04280 bbe335a8eebf203d0a4809f417d0428c 118 Gene3D G3DSA:1.10.490.10 1 118 6.4E-33 T 28-03-2018 CIG75_RS17095 ef96eeaee03d72ffe7e3af65f9e6a38c 63 Gene3D G3DSA:3.30.240.20 3 62 1.4E-15 T 28-03-2018 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain CIG75_RS17095 ef96eeaee03d72ffe7e3af65f9e6a38c 63 Pfam PF04239 Protein of unknown function (DUF421) 4 61 5.3E-8 T 28-03-2018 IPR007353 Protein of unknown function DUF421 CIG75_RS20340 900374e42b8c3a5b9006fbdefba0100e 95 Pfam PF06257 Biofilm formation stimulator VEG 6 75 3.5E-31 T 28-03-2018 IPR009366 Protein Veg GO:0042710 CIG75_RS20340 900374e42b8c3a5b9006fbdefba0100e 95 Gene3D G3DSA:2.30.30.100 4 77 4.3E-32 T 28-03-2018 CIG75_RS20340 900374e42b8c3a5b9006fbdefba0100e 95 PIRSF PIRSF037257 1 86 4.3E-35 T 28-03-2018 IPR009366 Protein Veg GO:0042710 CIG75_RS11415 c919068a820aaa79a6050abe015d72d8 223 Pfam PF00033 Cytochrome b/b6/petB 37 218 3.3E-55 T 28-03-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 CIG75_RS11415 c919068a820aaa79a6050abe015d72d8 223 Gene3D G3DSA:1.20.810.10 2 223 2.5E-79 T 28-03-2018 IPR027387 Cytochrome b/b6-like domain Reactome: R-HSA-611105 CIG75_RS11415 c919068a820aaa79a6050abe015d72d8 223 PIRSF PIRSF000032 2 223 2.3E-95 T 28-03-2018 IPR023530 Cytochrome b6, PetB GO:0005506|GO:0016021|GO:0020037|GO:0022900|GO:0045158 CIG75_RS11415 c919068a820aaa79a6050abe015d72d8 223 SUPERFAMILY SSF81342 6 222 9.26E-68 T 28-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 CIG75_RS06565 1da9a6f7f4042cb6b30396851310dd31 1116 SUPERFAMILY SSF56801 461 1023 3.92E-170 T 28-03-2018 CIG75_RS06565 1da9a6f7f4042cb6b30396851310dd31 1116 Pfam PF00550 Phosphopantetheine attachment site 1012 1073 8.2E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS06565 1da9a6f7f4042cb6b30396851310dd31 1116 Gene3D G3DSA:2.30.38.10 813 892 7.4E-24 T 28-03-2018 CIG75_RS06565 1da9a6f7f4042cb6b30396851310dd31 1116 PIRSF PIRSF001617 949 1111 1.8E-17 T 28-03-2018 CIG75_RS06565 1da9a6f7f4042cb6b30396851310dd31 1116 PIRSF PIRSF001617 632 873 4.3E-17 T 28-03-2018 CIG75_RS06565 1da9a6f7f4042cb6b30396851310dd31 1116 PIRSF PIRSF001617 870 955 6.5E-20 T 28-03-2018 CIG75_RS06565 1da9a6f7f4042cb6b30396851310dd31 1116 PIRSF PIRSF001617 226 614 4.0E-27 T 28-03-2018 CIG75_RS06565 1da9a6f7f4042cb6b30396851310dd31 1116 SUPERFAMILY SSF47336 1003 1071 9.16E-16 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS06565 1da9a6f7f4042cb6b30396851310dd31 1116 Gene3D G3DSA:3.30.300.30 897 1014 6.1E-40 T 28-03-2018 CIG75_RS06565 1da9a6f7f4042cb6b30396851310dd31 1116 Gene3D G3DSA:3.30.559.10 21 242 3.8E-40 T 28-03-2018 CIG75_RS06565 1da9a6f7f4042cb6b30396851310dd31 1116 Pfam PF00501 AMP-binding enzyme 505 902 1.1E-109 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CIG75_RS06565 1da9a6f7f4042cb6b30396851310dd31 1116 Gene3D G3DSA:3.40.50.980 658 812 2.5E-42 T 28-03-2018 CIG75_RS06565 1da9a6f7f4042cb6b30396851310dd31 1116 ProSitePatterns PS00455 Putative AMP-binding domain signature. 652 663 - T 28-03-2018 IPR020845 AMP-binding, conserved site CIG75_RS06565 1da9a6f7f4042cb6b30396851310dd31 1116 Pfam PF00668 Condensation domain 50 483 9.3E-93 T 28-03-2018 IPR001242 Condensation domain CIG75_RS06565 1da9a6f7f4042cb6b30396851310dd31 1116 Pfam PF13193 AMP-binding enzyme C-terminal domain 910 985 1.2E-14 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CIG75_RS06565 1da9a6f7f4042cb6b30396851310dd31 1116 SUPERFAMILY SSF52777 226 487 2.11E-55 T 28-03-2018 CIG75_RS06565 1da9a6f7f4042cb6b30396851310dd31 1116 SUPERFAMILY SSF52777 51 218 1.56E-45 T 28-03-2018 CIG75_RS06565 1da9a6f7f4042cb6b30396851310dd31 1116 Gene3D G3DSA:1.10.1200.10 1015 1076 3.6E-16 T 28-03-2018 CIG75_RS06565 1da9a6f7f4042cb6b30396851310dd31 1116 Gene3D G3DSA:3.40.50.980 496 657 3.0E-49 T 28-03-2018 CIG75_RS06565 1da9a6f7f4042cb6b30396851310dd31 1116 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1034 1049 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS06565 1da9a6f7f4042cb6b30396851310dd31 1116 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 526 926 2.3E-136 T 28-03-2018 IPR010071 Amino acid adenylation domain CIG75_RS15470 5a441aef62fcd00fa018caf0957eb838 408 Pfam PF05193 Peptidase M16 inactive domain 166 337 5.2E-34 T 28-03-2018 IPR007863 Peptidase M16, C-terminal CIG75_RS15470 5a441aef62fcd00fa018caf0957eb838 408 Gene3D G3DSA:3.30.830.10 218 408 9.6E-37 T 28-03-2018 CIG75_RS15470 5a441aef62fcd00fa018caf0957eb838 408 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 35 58 - T 28-03-2018 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 CIG75_RS15470 5a441aef62fcd00fa018caf0957eb838 408 Gene3D G3DSA:3.30.830.10 1 215 1.1E-54 T 28-03-2018 CIG75_RS15470 5a441aef62fcd00fa018caf0957eb838 408 SUPERFAMILY SSF63411 228 404 5.83E-37 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CIG75_RS15470 5a441aef62fcd00fa018caf0957eb838 408 SUPERFAMILY SSF63411 4 205 8.56E-53 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CIG75_RS15470 5a441aef62fcd00fa018caf0957eb838 408 Pfam PF00675 Insulinase (Peptidase family M16) 15 137 8.9E-23 T 28-03-2018 IPR011765 Peptidase M16, N-terminal CIG75_RS12975 faf499e4d77414ec1b0eba96d70b0938 133 SUPERFAMILY SSF47413 2 69 5.09E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CIG75_RS12975 faf499e4d77414ec1b0eba96d70b0938 133 Gene3D G3DSA:1.10.1660.10 68 128 0.29 T 28-03-2018 CIG75_RS12975 faf499e4d77414ec1b0eba96d70b0938 133 Pfam PF01381 Helix-turn-helix 7 61 2.4E-12 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS12975 faf499e4d77414ec1b0eba96d70b0938 133 Gene3D G3DSA:1.10.260.40 2 67 5.4E-19 T 28-03-2018 CIG75_RS12975 faf499e4d77414ec1b0eba96d70b0938 133 SMART SM00530 6 61 7.8E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS14310 cd862ccd8f84da3329afd82e20ff0d5b 293 Gene3D G3DSA:3.40.190.10 176 266 1.3E-16 T 28-03-2018 CIG75_RS14310 cd862ccd8f84da3329afd82e20ff0d5b 293 SUPERFAMILY SSF46785 1 86 4.29E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS14310 cd862ccd8f84da3329afd82e20ff0d5b 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 5.7E-23 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CIG75_RS14310 cd862ccd8f84da3329afd82e20ff0d5b 293 SUPERFAMILY SSF53850 88 290 6.65E-32 T 28-03-2018 CIG75_RS14310 cd862ccd8f84da3329afd82e20ff0d5b 293 Pfam PF03466 LysR substrate binding domain 88 289 2.1E-35 T 28-03-2018 IPR005119 LysR, substrate-binding CIG75_RS14310 cd862ccd8f84da3329afd82e20ff0d5b 293 Gene3D G3DSA:1.10.10.10 1 83 1.6E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS14310 cd862ccd8f84da3329afd82e20ff0d5b 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.2E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CIG75_RS14310 cd862ccd8f84da3329afd82e20ff0d5b 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.2E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CIG75_RS14310 cd862ccd8f84da3329afd82e20ff0d5b 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.2E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CIG75_RS14310 cd862ccd8f84da3329afd82e20ff0d5b 293 Gene3D G3DSA:3.40.190.10 88 175 5.9E-15 T 28-03-2018 CIG75_RS08045 dfe9f9c62859b066973adc5adba8aed7 300 Gene3D G3DSA:3.30.70.1070 104 171 2.7E-6 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 CIG75_RS08045 dfe9f9c62859b066973adc5adba8aed7 300 SUPERFAMILY SSF110997 106 170 1.16E-6 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 CIG75_RS08045 dfe9f9c62859b066973adc5adba8aed7 300 Pfam PF05036 Sporulation related domain 106 170 8.7E-5 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 CIG75_RS17180 d14302a9e3546262dd3b1f114ffd1512 694 SMART SM00304 239 291 8.2E-5 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CIG75_RS17180 d14302a9e3546262dd3b1f114ffd1512 694 Gene3D G3DSA:1.10.287.950 267 354 7.2E-9 T 28-03-2018 CIG75_RS17180 d14302a9e3546262dd3b1f114ffd1512 694 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 365 548 6.2E-40 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CIG75_RS17180 d14302a9e3546262dd3b1f114ffd1512 694 SUPERFAMILY SSF58104 326 594 1.83E-66 T 28-03-2018 CIG75_RS17180 d14302a9e3546262dd3b1f114ffd1512 694 SUPERFAMILY SSF58104 259 293 1.83E-66 T 28-03-2018 CIG75_RS17180 d14302a9e3546262dd3b1f114ffd1512 694 Pfam PF12729 Four helix bundle sensory module for signal transduction 31 200 1.3E-16 T 28-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain CIG75_RS17180 d14302a9e3546262dd3b1f114ffd1512 694 Gene3D G3DSA:1.20.120.30 50 213 1.6E-11 T 28-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain CIG75_RS17180 d14302a9e3546262dd3b1f114ffd1512 694 Gene3D G3DSA:1.10.287.950 355 599 3.4E-52 T 28-03-2018 CIG75_RS17180 d14302a9e3546262dd3b1f114ffd1512 694 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 447 476 1.2E-6 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CIG75_RS17180 d14302a9e3546262dd3b1f114ffd1512 694 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 334 363 1.2E-6 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CIG75_RS17180 d14302a9e3546262dd3b1f114ffd1512 694 SMART SM00283 320 595 1.5E-70 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CIG75_RS16790 d24a307cfe4fa17150005aa66dd35c06 337 PIRSF PIRSF001439 1 337 1.4E-91 T 28-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 CIG75_RS16790 d24a307cfe4fa17150005aa66dd35c06 337 SUPERFAMILY SSF51735 6 336 1.01E-78 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS16790 d24a307cfe4fa17150005aa66dd35c06 337 Gene3D G3DSA:3.30.1780.10 4 148 2.0E-33 T 28-03-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 CIG75_RS16790 d24a307cfe4fa17150005aa66dd35c06 337 TIGRFAM TIGR03944 dehyd_SbnB_fam: 2,3-diaminopropionate biosynthesis protein SbnB 7 337 1.5E-123 T 28-03-2018 IPR023866 2,3-diaminopropionate biosynthesis protein SbnB CIG75_RS16790 d24a307cfe4fa17150005aa66dd35c06 337 Gene3D G3DSA:3.40.50.720 149 309 8.0E-26 T 28-03-2018 CIG75_RS16790 d24a307cfe4fa17150005aa66dd35c06 337 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 25 328 1.4E-65 T 28-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 CIG75_RS09820 ed314c0cae26563584a294c65da83d98 644 SMART SM00230 241 644 4.1E-5 T 28-03-2018 IPR001300 Peptidase C2, calpain, catalytic domain GO:0004198|GO:0005622|GO:0006508 Reactome: R-HSA-1474228 CIG75_RS09820 ed314c0cae26563584a294c65da83d98 644 Pfam PF00648 Calpain family cysteine protease 292 641 3.5E-19 T 28-03-2018 IPR001300 Peptidase C2, calpain, catalytic domain GO:0004198|GO:0005622|GO:0006508 Reactome: R-HSA-1474228 CIG75_RS09820 ed314c0cae26563584a294c65da83d98 644 Gene3D G3DSA:3.90.70.10 519 643 1.3E-14 T 28-03-2018 CIG75_RS09820 ed314c0cae26563584a294c65da83d98 644 SUPERFAMILY SSF54001 523 641 2.33E-31 T 28-03-2018 CIG75_RS09820 ed314c0cae26563584a294c65da83d98 644 SUPERFAMILY SSF54001 276 431 2.33E-31 T 28-03-2018 CIG75_RS10825 2ae67b2b31971ffbd40be00ced34518b 81 TIGRFAM TIGR02383 Hfq: RNA chaperone Hfq 12 71 1.9E-31 T 28-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 CIG75_RS10825 2ae67b2b31971ffbd40be00ced34518b 81 Gene3D G3DSA:2.30.30.100 10 80 1.2E-32 T 28-03-2018 CIG75_RS10825 2ae67b2b31971ffbd40be00ced34518b 81 SUPERFAMILY SSF50182 12 71 1.31E-23 T 28-03-2018 IPR010920 LSM domain CIG75_RS10825 2ae67b2b31971ffbd40be00ced34518b 81 Pfam PF17209 Hfq protein 13 75 9.4E-33 T 28-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 CIG75_RS10825 2ae67b2b31971ffbd40be00ced34518b 81 Hamap MF_00436 RNA-binding protein Hfq [hfq]. 7 71 29.011 T 28-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 CIG75_RS03210 5ceca57c6eafc3b9cfd02c3d7c2d398f 195 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 27 186 1.9E-12 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS03210 5ceca57c6eafc3b9cfd02c3d7c2d398f 195 SUPERFAMILY SSF88946 28 90 1.31E-5 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS03210 5ceca57c6eafc3b9cfd02c3d7c2d398f 195 Gene3D G3DSA:1.10.1740.10 10 98 6.2E-6 T 28-03-2018 CIG75_RS03210 5ceca57c6eafc3b9cfd02c3d7c2d398f 195 Gene3D G3DSA:1.10.10.10 144 190 3.7E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS03210 5ceca57c6eafc3b9cfd02c3d7c2d398f 195 SUPERFAMILY SSF46894 142 187 1.26E-8 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CIG75_RS03210 5ceca57c6eafc3b9cfd02c3d7c2d398f 195 Pfam PF00196 Bacterial regulatory proteins, luxR family 144 187 3.2E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CIG75_RS03210 5ceca57c6eafc3b9cfd02c3d7c2d398f 195 SMART SM00421 142 190 0.004 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CIG75_RS05580 0999e73052128d360c57f49c3d5010af 429 SMART SM01329 28 425 7.0E-186 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CIG75_RS05580 0999e73052128d360c57f49c3d5010af 429 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 29 424 7.1E-117 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CIG75_RS05580 0999e73052128d360c57f49c3d5010af 429 TIGRFAM TIGR00183 prok_nadp_idh: isocitrate dehydrogenase, NADP-dependent 2 429 6.7E-222 T 28-03-2018 IPR004439 Isocitrate dehydrogenase NADP-dependent, dimeric, prokaryotic GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 CIG75_RS05580 0999e73052128d360c57f49c3d5010af 429 Gene3D G3DSA:3.40.718.10 17 429 9.1E-137 T 28-03-2018 CIG75_RS05580 0999e73052128d360c57f49c3d5010af 429 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 314 333 - T 28-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 CIG75_RS05580 0999e73052128d360c57f49c3d5010af 429 SUPERFAMILY SSF53659 2 429 2.88E-143 T 28-03-2018 CIG75_RS16780 bd61b8a36f08141aef38c4eff3cc2aa7 294 Pfam PF11575 FhuF 2Fe-2S C-terminal domain 259 279 6.0E-6 T 28-03-2018 IPR024726 Ferric iron reductase, C-terminal GO:0051537 CIG75_RS16780 bd61b8a36f08141aef38c4eff3cc2aa7 294 Pfam PF06276 Ferric iron reductase FhuF-like transporter 88 229 2.6E-13 T 28-03-2018 IPR022770 Ferric iron reductase FhuF domain CIG75_RS17170 fa128e4ec532e78f17c7f0a985985711 388 Gene3D G3DSA:3.40.50.10680 149 385 9.3E-59 T 28-03-2018 CIG75_RS17170 fa128e4ec532e78f17c7f0a985985711 388 Hamap MF_00973 Gluconeogenesis factor. 68 381 35.58 T 28-03-2018 IPR010119 Gluconeogenesis factor CIG75_RS17170 fa128e4ec532e78f17c7f0a985985711 388 TIGRFAM TIGR01826 CofD_related: conserved hypothetical protein 72 378 3.4E-118 T 28-03-2018 IPR010119 Gluconeogenesis factor CIG75_RS17170 fa128e4ec532e78f17c7f0a985985711 388 Pfam PF01933 Uncharacterised protein family UPF0052 72 357 9.5E-108 T 28-03-2018 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 CIG75_RS17170 fa128e4ec532e78f17c7f0a985985711 388 SUPERFAMILY SSF142338 69 375 1.57E-103 T 28-03-2018 CIG75_RS13485 c1ecd674a442289d49ebd286ad750b00 305 Gene3D G3DSA:3.90.78.10 221 305 1.3E-30 T 28-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CIG75_RS13485 c1ecd674a442289d49ebd286ad750b00 305 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 305 93.196 T 28-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CIG75_RS13485 c1ecd674a442289d49ebd286ad750b00 305 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 24 301 3.0E-83 T 28-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CIG75_RS13485 c1ecd674a442289d49ebd286ad750b00 305 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 203 300 1.6E-31 T 28-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CIG75_RS13485 c1ecd674a442289d49ebd286ad750b00 305 SUPERFAMILY SSF56194 198 302 2.09E-38 T 28-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CIG75_RS13485 c1ecd674a442289d49ebd286ad750b00 305 Gene3D G3DSA:3.30.465.10 91 220 7.4E-36 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CIG75_RS13485 c1ecd674a442289d49ebd286ad750b00 305 Gene3D G3DSA:3.30.43.10 16 90 1.1E-24 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CIG75_RS13485 c1ecd674a442289d49ebd286ad750b00 305 SUPERFAMILY SSF56176 16 196 3.6E-46 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CIG75_RS13485 c1ecd674a442289d49ebd286ad750b00 305 Pfam PF01565 FAD binding domain 37 167 3.5E-25 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CIG75_RS14180 134909bd2478f49f0a66d9d9cbf849d4 185 Pfam PF10646 Sporulation and spore germination 62 169 1.8E-9 T 28-03-2018 IPR019606 GerMN domain CIG75_RS14180 134909bd2478f49f0a66d9d9cbf849d4 185 Gene3D G3DSA:3.40.190.10 1 180 2.4E-8 T 28-03-2018 CIG75_RS00040 3ffb83c439c6bfe42133d2dbf538d934 471 Gene3D G3DSA:3.90.100.10 382 471 1.6E-26 T 28-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 CIG75_RS00040 3ffb83c439c6bfe42133d2dbf538d934 471 ProSitePatterns PS00703 Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site. 219 233 - T 28-03-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 CIG75_RS00040 3ffb83c439c6bfe42133d2dbf538d934 471 SUPERFAMILY SSF55904 329 469 4.18E-32 T 28-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 CIG75_RS00040 3ffb83c439c6bfe42133d2dbf538d934 471 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 6 298 5.7E-79 T 28-03-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 CIG75_RS00040 3ffb83c439c6bfe42133d2dbf538d934 471 SUPERFAMILY SSF53383 6 370 1.09E-91 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CIG75_RS00040 3ffb83c439c6bfe42133d2dbf538d934 471 Gene3D G3DSA:3.90.1150.10 306 381 1.9E-16 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CIG75_RS00040 3ffb83c439c6bfe42133d2dbf538d934 471 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 403 459 3.3E-15 T 28-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 CIG75_RS00040 3ffb83c439c6bfe42133d2dbf538d934 471 Gene3D G3DSA:3.40.640.10 5 282 9.8E-50 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CIG75_RS01580 6c73dd81ccf4acfeaea51fa6bf461375 506 Gene3D G3DSA:1.10.3720.10 1 312 7.6E-27 T 28-03-2018 CIG75_RS01580 6c73dd81ccf4acfeaea51fa6bf461375 506 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 106 318 3.6E-10 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CIG75_RS01580 6c73dd81ccf4acfeaea51fa6bf461375 506 SUPERFAMILY SSF161098 82 303 2.83E-12 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CIG75_RS01640 c2d33de56928b33ca26a9131ed044ff3 143 SUPERFAMILY SSF53927 7 138 6.52E-40 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CIG75_RS01640 c2d33de56928b33ca26a9131ed044ff3 143 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 5 115 8.0E-30 T 28-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain CIG75_RS01640 c2d33de56928b33ca26a9131ed044ff3 143 TIGRFAM TIGR02571 ComEB: ComE operon protein 2 2 138 4.3E-69 T 28-03-2018 IPR013404 Competence operon E, ComEB CIG75_RS01640 c2d33de56928b33ca26a9131ed044ff3 143 PIRSF PIRSF006019 1 143 2.4E-55 T 28-03-2018 IPR016473 Deoxycytidylate deaminase GO:0004132|GO:0006220|GO:0008270 KEGG: 00240+3.5.4.12|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CIG75_RS01640 c2d33de56928b33ca26a9131ed044ff3 143 Gene3D G3DSA:3.40.140.10 2 143 1.2E-38 T 28-03-2018 CIG75_RS01640 c2d33de56928b33ca26a9131ed044ff3 143 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 69 104 - T 28-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 CIG75_RS00765 591a62002dc65ef3974a86354c6ad803 124 Pfam PF14270 Domain of unknown function (DUF4358) 11 107 3.5E-27 T 28-03-2018 IPR025648 Protein of unknown function DUF4358 CIG75_RS14070 c95938a4f4252a1552fd7dde159676e8 89 Pfam PF00581 Rhodanese-like domain 4 83 1.8E-17 T 28-03-2018 IPR001763 Rhodanese-like domain CIG75_RS14070 c95938a4f4252a1552fd7dde159676e8 89 SMART SM00450 1 87 1.3E-14 T 28-03-2018 IPR001763 Rhodanese-like domain CIG75_RS14070 c95938a4f4252a1552fd7dde159676e8 89 Gene3D G3DSA:3.40.250.10 1 88 7.1E-22 T 28-03-2018 IPR001763 Rhodanese-like domain CIG75_RS14070 c95938a4f4252a1552fd7dde159676e8 89 SUPERFAMILY SSF52821 6 84 8.51E-24 T 28-03-2018 IPR001763 Rhodanese-like domain CIG75_RS01145 e2b377832d645c9e6f148d8c349d4b35 487 Pfam PF12476 Protein of unknown function (DUF3696) 435 474 5.6E-9 T 28-03-2018 IPR022532 Domain of unknown function DUF3696, C-terminal CIG75_RS01145 e2b377832d645c9e6f148d8c349d4b35 487 Gene3D G3DSA:3.40.50.300 14 430 2.6E-22 T 28-03-2018 CIG75_RS01145 e2b377832d645c9e6f148d8c349d4b35 487 PIRSF PIRSF034888 251 486 1.7E-36 T 28-03-2018 IPR014592 Predicted P-loop ATP-binding protein, VCA0200 CIG75_RS01145 e2b377832d645c9e6f148d8c349d4b35 487 PIRSF PIRSF034888 14 104 1.6E-11 T 28-03-2018 IPR014592 Predicted P-loop ATP-binding protein, VCA0200 CIG75_RS01145 e2b377832d645c9e6f148d8c349d4b35 487 SUPERFAMILY SSF52540 192 254 9.7E-15 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS01145 e2b377832d645c9e6f148d8c349d4b35 487 SUPERFAMILY SSF52540 324 424 9.7E-15 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS01145 e2b377832d645c9e6f148d8c349d4b35 487 SUPERFAMILY SSF52540 14 85 9.7E-15 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS01145 e2b377832d645c9e6f148d8c349d4b35 487 Pfam PF13175 AAA ATPase domain 14 422 3.6E-25 T 28-03-2018 CIG75_RS16580 080ccf25ecd13fbf686ae636a95d3f2a 197 Gene3D G3DSA:1.10.10.60 1 66 2.5E-20 T 28-03-2018 CIG75_RS16580 080ccf25ecd13fbf686ae636a95d3f2a 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 60 3.0E-16 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CIG75_RS16580 080ccf25ecd13fbf686ae636a95d3f2a 197 SUPERFAMILY SSF46689 2 76 1.4E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CIG75_RS16580 080ccf25ecd13fbf686ae636a95d3f2a 197 ProSitePatterns PS01081 TetR-type HTH domain signature. 28 59 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CIG75_RS16580 080ccf25ecd13fbf686ae636a95d3f2a 197 SUPERFAMILY SSF48498 85 195 5.26E-9 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CIG75_RS16580 080ccf25ecd13fbf686ae636a95d3f2a 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 8.8E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CIG75_RS16580 080ccf25ecd13fbf686ae636a95d3f2a 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 8.8E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CIG75_RS16580 080ccf25ecd13fbf686ae636a95d3f2a 197 Gene3D G3DSA:1.10.357.10 67 197 2.3E-10 T 28-03-2018 CIG75_RS15550 67f5ddf3d6cf06feacfa2139b21ea12d 580 Pfam PF01432 Peptidase family M3 184 564 4.2E-72 T 28-03-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 CIG75_RS15550 67f5ddf3d6cf06feacfa2139b21ea12d 580 Pfam PF08439 Oligopeptidase F 94 162 9.2E-22 T 28-03-2018 IPR013647 Oligopeptidase F, N-terminal domain CIG75_RS15550 67f5ddf3d6cf06feacfa2139b21ea12d 580 Gene3D G3DSA:1.10.1370.10 96 574 2.7E-38 T 28-03-2018 CIG75_RS15550 67f5ddf3d6cf06feacfa2139b21ea12d 580 SUPERFAMILY SSF55486 6 559 6.0E-119 T 28-03-2018 CIG75_RS15550 67f5ddf3d6cf06feacfa2139b21ea12d 580 TIGRFAM TIGR00181 pepF: oligoendopeptidase F 1 575 3.7E-194 T 28-03-2018 IPR004438 Peptidase M3B, oligoendopeptidase F GO:0004222|GO:0006508 CIG75_RS08765 e889c0f94a47f1d243d71dceaf859b8a 218 Pfam PF00677 Lumazine binding domain 99 183 9.8E-25 T 28-03-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CIG75_RS08765 e889c0f94a47f1d243d71dceaf859b8a 218 Pfam PF00677 Lumazine binding domain 3 86 2.3E-24 T 28-03-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CIG75_RS08765 e889c0f94a47f1d243d71dceaf859b8a 218 Gene3D G3DSA:2.40.30.20 1 88 2.4E-30 T 28-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CIG75_RS08765 e889c0f94a47f1d243d71dceaf859b8a 218 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 194 1.5E-71 T 28-03-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CIG75_RS08765 e889c0f94a47f1d243d71dceaf859b8a 218 PIRSF PIRSF000498 1 210 2.7E-76 T 28-03-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CIG75_RS08765 e889c0f94a47f1d243d71dceaf859b8a 218 Gene3D G3DSA:2.40.30.20 93 190 3.1E-32 T 28-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CIG75_RS08765 e889c0f94a47f1d243d71dceaf859b8a 218 SUPERFAMILY SSF63380 1 89 7.14E-27 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CIG75_RS08765 e889c0f94a47f1d243d71dceaf859b8a 218 SUPERFAMILY SSF63380 92 194 9.35E-32 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CIG75_RS18890 bf8bbe1e0bb26d0891e5056491bf9aac 285 Gene3D G3DSA:3.40.630.40 1 184 1.3E-43 T 28-03-2018 CIG75_RS18890 bf8bbe1e0bb26d0891e5056491bf9aac 285 SUPERFAMILY SSF53187 3 183 1.57E-40 T 28-03-2018 CIG75_RS18890 bf8bbe1e0bb26d0891e5056491bf9aac 285 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 5 177 4.8E-37 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CIG75_RS18890 bf8bbe1e0bb26d0891e5056491bf9aac 285 SMART SM00646 63 178 2.8E-14 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CIG75_RS16905 ec843e0f0a7f05e55389fa16590d9552 460 Gene3D G3DSA:3.40.50.880 222 415 5.2E-21 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CIG75_RS16905 ec843e0f0a7f05e55389fa16590d9552 460 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 251 441 9.0E-38 T 28-03-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 CIG75_RS16905 ec843e0f0a7f05e55389fa16590d9552 460 Hamap MF_00027 Cobyrinate a,c-diamide synthase [cbiA]. 4 442 45.691 T 28-03-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 CIG75_RS16905 ec843e0f0a7f05e55389fa16590d9552 460 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 8 192 1.1E-17 T 28-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain CIG75_RS16905 ec843e0f0a7f05e55389fa16590d9552 460 Gene3D G3DSA:3.40.50.300 2 180 5.5E-37 T 28-03-2018 CIG75_RS16905 ec843e0f0a7f05e55389fa16590d9552 460 SUPERFAMILY SSF52317 251 450 1.75E-31 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CIG75_RS16905 ec843e0f0a7f05e55389fa16590d9552 460 SUPERFAMILY SSF52540 6 198 1.14E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS16905 ec843e0f0a7f05e55389fa16590d9552 460 TIGRFAM TIGR00379 cobB: cobyrinic acid a,c-diamide synthase 6 453 1.4E-145 T 28-03-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 CIG75_RS15295 b3f8413d5c745a9af4f5644abaf9ee6a 206 Pfam PF09335 SNARE associated Golgi protein 38 163 7.5E-24 T 28-03-2018 IPR032816 SNARE associated Golgi protein CIG75_RS07095 43db72d0e44d403d5d8dceb619316f99 364 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 6 353 2.7E-110 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CIG75_RS07095 43db72d0e44d403d5d8dceb619316f99 364 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 106 117 - T 28-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CIG75_RS07095 43db72d0e44d403d5d8dceb619316f99 364 SUPERFAMILY SSF56059 139 356 2.05E-54 T 28-03-2018 CIG75_RS07095 43db72d0e44d403d5d8dceb619316f99 364 Gene3D G3DSA:3.30.1490.20 154 214 1.7E-18 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CIG75_RS07095 43db72d0e44d403d5d8dceb619316f99 364 PIRSF PIRSF039102 2 362 3.3E-115 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CIG75_RS07095 43db72d0e44d403d5d8dceb619316f99 364 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 295 324 - T 28-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CIG75_RS07095 43db72d0e44d403d5d8dceb619316f99 364 Pfam PF07478 D-ala D-ala ligase C-terminus 149 351 3.7E-73 T 28-03-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CIG75_RS07095 43db72d0e44d403d5d8dceb619316f99 364 Gene3D G3DSA:3.40.50.20 1 149 1.8E-45 T 28-03-2018 CIG75_RS07095 43db72d0e44d403d5d8dceb619316f99 364 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 5 354 41.437 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CIG75_RS07095 43db72d0e44d403d5d8dceb619316f99 364 SUPERFAMILY SSF52440 4 138 2.01E-34 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CIG75_RS07095 43db72d0e44d403d5d8dceb619316f99 364 Pfam PF01820 D-ala D-ala ligase N-terminus 6 128 8.2E-31 T 28-03-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CIG75_RS07095 43db72d0e44d403d5d8dceb619316f99 364 Gene3D G3DSA:3.30.470.20 215 363 3.1E-43 T 28-03-2018 CIG75_RS09955 57185771e7a6b869b1a89cffc933dbf2 342 Pfam PF01008 Initiation factor 2 subunit family 42 331 1.5E-88 T 28-03-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 CIG75_RS09955 57185771e7a6b869b1a89cffc933dbf2 342 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 3 331 1.7E-138 T 28-03-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 CIG75_RS09955 57185771e7a6b869b1a89cffc933dbf2 342 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 28 331 9.9E-121 T 28-03-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 CIG75_RS09955 57185771e7a6b869b1a89cffc933dbf2 342 Gene3D G3DSA:3.40.50.10470 143 340 1.5E-72 T 28-03-2018 CIG75_RS09955 57185771e7a6b869b1a89cffc933dbf2 342 Gene3D G3DSA:1.20.120.420 1 142 1.8E-48 T 28-03-2018 IPR027363 Methylthioribose-1-phosphate isomerase-like, N-terminal domain KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 CIG75_RS09955 57185771e7a6b869b1a89cffc933dbf2 342 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 3 342 40.869 T 28-03-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 CIG75_RS09955 57185771e7a6b869b1a89cffc933dbf2 342 SUPERFAMILY SSF100950 2 335 2.09E-123 T 28-03-2018 CIG75_RS02640 a2470a154f5dd4e10d9851107bb0825e 252 SUPERFAMILY SSF52972 2 187 2.88E-28 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CIG75_RS02640 a2470a154f5dd4e10d9851107bb0825e 252 Pfam PF01725 Ham1 family 3 183 1.3E-22 T 28-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 CIG75_RS02640 a2470a154f5dd4e10d9851107bb0825e 252 Gene3D G3DSA:3.90.950.10 1 195 1.1E-29 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CIG75_RS05710 e4782d45ed6e2bfa5b33616b011a4769 888 Gene3D G3DSA:1.20.1430.10 409 529 6.5E-33 T 28-03-2018 IPR015293 Domain of unknown function DUF1957 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 CIG75_RS05710 e4782d45ed6e2bfa5b33616b011a4769 888 Gene3D G3DSA:3.20.110.10 1 407 3.4E-94 T 28-03-2018 IPR027291 Glycoside hydrolase 38/57, N-terminal domain CIG75_RS05710 e4782d45ed6e2bfa5b33616b011a4769 888 Gene3D G3DSA:3.40.50.2000 530 735 1.5E-17 T 28-03-2018 CIG75_RS05710 e4782d45ed6e2bfa5b33616b011a4769 888 SUPERFAMILY SSF88688 411 525 7.52E-30 T 28-03-2018 IPR028995 Glycoside hydrolase families 57/38, central domain CIG75_RS05710 e4782d45ed6e2bfa5b33616b011a4769 888 Gene3D G3DSA:3.40.50.2000 742 850 2.5E-28 T 28-03-2018 CIG75_RS05710 e4782d45ed6e2bfa5b33616b011a4769 888 SUPERFAMILY SSF88713 3 407 3.11E-100 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CIG75_RS05710 e4782d45ed6e2bfa5b33616b011a4769 888 SUPERFAMILY SSF53756 536 837 1.17E-67 T 28-03-2018 CIG75_RS05710 e4782d45ed6e2bfa5b33616b011a4769 888 Pfam PF00534 Glycosyl transferases group 1 735 837 4.6E-27 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CIG75_RS05710 e4782d45ed6e2bfa5b33616b011a4769 888 Pfam PF13439 Glycosyltransferase Family 4 549 722 7.4E-31 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CIG75_RS05710 e4782d45ed6e2bfa5b33616b011a4769 888 Pfam PF09210 Domain of unknown function (DUF1957) 418 520 8.8E-25 T 28-03-2018 IPR015293 Domain of unknown function DUF1957 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 CIG75_RS05710 e4782d45ed6e2bfa5b33616b011a4769 888 Pfam PF03065 Glycosyl hydrolase family 57 8 357 2.2E-44 T 28-03-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 CIG75_RS02000 91adbfab00dcf709812334c0098dbc6b 505 Pfam PF00361 Proton-conducting membrane transporter 136 426 1.6E-56 T 28-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CIG75_RS02000 91adbfab00dcf709812334c0098dbc6b 505 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 394 420 3.9E-28 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CIG75_RS02000 91adbfab00dcf709812334c0098dbc6b 505 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 142 161 3.9E-28 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CIG75_RS02000 91adbfab00dcf709812334c0098dbc6b 505 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 254 278 3.9E-28 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CIG75_RS02000 91adbfab00dcf709812334c0098dbc6b 505 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 342 361 3.9E-28 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CIG75_RS02000 91adbfab00dcf709812334c0098dbc6b 505 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 172 196 3.9E-28 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CIG75_RS02000 91adbfab00dcf709812334c0098dbc6b 505 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 5 501 9.8E-148 T 28-03-2018 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CIG75_RS10090 e43a8d17e56892d4a853af07861385b4 444 SUPERFAMILY SSF55931 106 441 1.96E-129 T 28-03-2018 CIG75_RS10090 e43a8d17e56892d4a853af07861385b4 444 SMART SM01230 105 354 1.0E-141 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CIG75_RS10090 e43a8d17e56892d4a853af07861385b4 444 Gene3D G3DSA:3.10.20.70 1 104 1.9E-38 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CIG75_RS10090 e43a8d17e56892d4a853af07861385b4 444 Gene3D G3DSA:3.30.590.10 105 444 5.6E-128 T 28-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 CIG75_RS10090 e43a8d17e56892d4a853af07861385b4 444 Pfam PF00120 Glutamine synthetase, catalytic domain 106 440 1.0E-138 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CIG75_RS10090 e43a8d17e56892d4a853af07861385b4 444 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 16 99 3.4E-31 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CIG75_RS10090 e43a8d17e56892d4a853af07861385b4 444 SUPERFAMILY SSF54368 4 104 6.02E-34 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CIG75_RS10090 e43a8d17e56892d4a853af07861385b4 444 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 6 441 1.6E-180 T 28-03-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CIG75_RS10090 e43a8d17e56892d4a853af07861385b4 444 ProSitePatterns PS00180 Glutamine synthetase signature 1. 51 69 - T 28-03-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 CIG75_RS10090 e43a8d17e56892d4a853af07861385b4 444 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 234 249 - T 28-03-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 CIG75_RS14525 701344845eac32aef22231284d9e43c6 310 SUPERFAMILY SSF52540 7 228 5.75E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS14525 701344845eac32aef22231284d9e43c6 310 SMART SM00382 34 213 5.9E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS14525 701344845eac32aef22231284d9e43c6 310 Pfam PF00005 ABC transporter 26 165 2.6E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS14525 701344845eac32aef22231284d9e43c6 310 Gene3D G3DSA:3.40.50.300 8 278 1.1E-60 T 28-03-2018 CIG75_RS14525 701344845eac32aef22231284d9e43c6 310 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS02400 2a5acaca4790dd06f060f0f26b49dd61 641 Gene3D G3DSA:3.90.1480.10 233 518 8.1E-44 T 28-03-2018 CIG75_RS02400 2a5acaca4790dd06f060f0f26b49dd61 641 Pfam PF01973 Protein of unknown function DUF115 225 393 9.6E-43 T 28-03-2018 IPR002826 6-hydroxymethylpterin diphosphokinase MptE-like CIG75_RS03375 54882b3487a9d6639843a060f913c4ac 442 Gene3D G3DSA:3.10.105.10 201 412 7.4E-19 T 28-03-2018 CIG75_RS03375 54882b3487a9d6639843a060f913c4ac 442 Gene3D G3DSA:3.90.76.10 13 170 4.7E-35 T 28-03-2018 CIG75_RS03375 54882b3487a9d6639843a060f913c4ac 442 SUPERFAMILY SSF53850 4 439 1.21E-81 T 28-03-2018 CIG75_RS03375 54882b3487a9d6639843a060f913c4ac 442 PIRSF PIRSF002741 3 442 1.5E-51 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CIG75_RS03375 54882b3487a9d6639843a060f913c4ac 442 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 25 355 4.5E-40 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CIG75_RS12325 2f9ec43f72a42a2b7370e444c9432d43 110 Gene3D G3DSA:1.10.10.10 1 108 2.0E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS12325 2f9ec43f72a42a2b7370e444c9432d43 110 SUPERFAMILY SSF88659 2 94 5.61E-32 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS12325 2f9ec43f72a42a2b7370e444c9432d43 110 Hamap MF_00245 UPF0122 protein . 2 104 19.643 T 28-03-2018 IPR007394 Putative helix-turn-helix protein, YlxM/p13-like CIG75_RS12325 2f9ec43f72a42a2b7370e444c9432d43 110 Pfam PF04297 Putative helix-turn-helix protein, YlxM / p13 like 2 90 4.2E-33 T 28-03-2018 IPR007394 Putative helix-turn-helix protein, YlxM/p13-like CIG75_RS03515 42773c838925ab07ad434a3203d9def4 195 SUPERFAMILY SSF55729 8 179 2.66E-42 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CIG75_RS03515 42773c838925ab07ad434a3203d9def4 195 Gene3D G3DSA:3.40.630.30 4 195 2.5E-30 T 28-03-2018 CIG75_RS03515 42773c838925ab07ad434a3203d9def4 195 Pfam PF13302 Acetyltransferase (GNAT) domain 15 153 2.3E-19 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CIG75_RS09980 88ae9c0800e5e98cfd452c49ddf34297 186 Gene3D G3DSA:3.10.450.40 26 86 7.8E-5 T 28-03-2018 CIG75_RS09980 88ae9c0800e5e98cfd452c49ddf34297 186 Gene3D G3DSA:3.10.450.40 93 181 2.4E-6 T 28-03-2018 CIG75_RS15895 0cb0eb220dc7966fd3dfbecac8780658 238 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 86 108 - T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CIG75_RS15895 0cb0eb220dc7966fd3dfbecac8780658 238 Pfam PF01066 CDP-alcohol phosphatidyltransferase 42 108 5.4E-11 T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CIG75_RS14200 33fc430b31c5ed6e4308fa24f9ef081c 298 Pfam PF13271 Domain of unknown function (DUF4062) 5 90 7.3E-17 T 28-03-2018 IPR025139 Domain of unknown function DUF4062 CIG75_RS14200 33fc430b31c5ed6e4308fa24f9ef081c 298 Gene3D G3DSA:3.40.50.450 1 175 1.6E-5 T 28-03-2018 CIG75_RS01085 9f1126d19fb03fa02eb3b6c3b8059cbf 167 Pfam PF07484 Phage Tail Collar Domain 7 63 2.3E-28 T 28-03-2018 IPR011083 Phage tail collar domain CIG75_RS01085 9f1126d19fb03fa02eb3b6c3b8059cbf 167 Gene3D G3DSA:3.90.1340.10 1 68 2.9E-23 T 28-03-2018 IPR011083 Phage tail collar domain CIG75_RS01085 9f1126d19fb03fa02eb3b6c3b8059cbf 167 SUPERFAMILY SSF88874 1 161 2.62E-44 T 28-03-2018 CIG75_RS05115 d9b4f57b8b240b7b041c23eb826e0a11 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 3.4E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS05115 d9b4f57b8b240b7b041c23eb826e0a11 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 3.4E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS05115 d9b4f57b8b240b7b041c23eb826e0a11 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 3.4E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS05115 d9b4f57b8b240b7b041c23eb826e0a11 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 249 1.9E-64 T 28-03-2018 CIG75_RS05115 d9b4f57b8b240b7b041c23eb826e0a11 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 5.9E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS05115 d9b4f57b8b240b7b041c23eb826e0a11 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 5.9E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS05115 d9b4f57b8b240b7b041c23eb826e0a11 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 5.9E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS05115 d9b4f57b8b240b7b041c23eb826e0a11 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 5.9E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS05115 d9b4f57b8b240b7b041c23eb826e0a11 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 5.9E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS05115 d9b4f57b8b240b7b041c23eb826e0a11 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 5.9E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS05115 d9b4f57b8b240b7b041c23eb826e0a11 252 SUPERFAMILY SSF51735 6 250 3.18E-78 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS05115 d9b4f57b8b240b7b041c23eb826e0a11 252 Gene3D G3DSA:3.40.50.720 45 252 6.9E-55 T 28-03-2018 CIG75_RS05115 d9b4f57b8b240b7b041c23eb826e0a11 252 Gene3D G3DSA:3.40.50.720 1 44 2.6E-11 T 28-03-2018 CIG75_RS08085 b31cc094fe73112b304415ab4c567ed8 633 Gene3D G3DSA:3.40.710.10 248 632 3.3E-94 T 28-03-2018 CIG75_RS08085 b31cc094fe73112b304415ab4c567ed8 633 Pfam PF00905 Penicillin binding protein transpeptidase domain 277 614 1.4E-67 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CIG75_RS08085 b31cc094fe73112b304415ab4c567ed8 633 Gene3D G3DSA:3.90.1310.10 28 247 1.8E-45 T 28-03-2018 CIG75_RS08085 b31cc094fe73112b304415ab4c567ed8 633 Pfam PF03717 Penicillin-binding Protein dimerisation domain 59 226 2.2E-39 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CIG75_RS08085 b31cc094fe73112b304415ab4c567ed8 633 SUPERFAMILY SSF56519 52 247 9.68E-44 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CIG75_RS08085 b31cc094fe73112b304415ab4c567ed8 633 SUPERFAMILY SSF56601 199 624 7.51E-80 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CIG75_RS09475 83267b0362be82fc401eca5b3b343808 993 Gene3D G3DSA:3.40.50.300 362 719 3.6E-4 T 28-03-2018 CIG75_RS09475 83267b0362be82fc401eca5b3b343808 993 Gene3D G3DSA:3.90.580.10 251 355 4.7E-4 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CIG75_RS09475 83267b0362be82fc401eca5b3b343808 993 SUPERFAMILY SSF57783 271 330 7.31E-5 T 28-03-2018 CIG75_RS13315 e30fd8163f5d719e8d804cdefababb55 402 SUPERFAMILY SSF56322 13 397 4.06E-94 T 28-03-2018 IPR005801 ADC synthase GO:0009058 CIG75_RS13315 e30fd8163f5d719e8d804cdefababb55 402 Pfam PF00425 chorismate binding enzyme 123 386 2.7E-77 T 28-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal CIG75_RS13315 e30fd8163f5d719e8d804cdefababb55 402 TIGRFAM TIGR00543 isochor_syn: isochorismate synthase 104 393 1.6E-85 T 28-03-2018 IPR004561 Isochorismate synthase GO:0008909|GO:0009058 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 CIG75_RS13315 e30fd8163f5d719e8d804cdefababb55 402 Gene3D G3DSA:3.60.120.10 2 397 2.0E-102 T 28-03-2018 IPR005801 ADC synthase GO:0009058 CIG75_RS17920 6fe518fd416f08165b063fac727cf9a0 159 SUPERFAMILY SSF55729 10 142 9.91E-14 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CIG75_RS17920 6fe518fd416f08165b063fac727cf9a0 159 Pfam PF00583 Acetyltransferase (GNAT) family 33 136 3.2E-5 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CIG75_RS17920 6fe518fd416f08165b063fac727cf9a0 159 Gene3D G3DSA:3.40.630.30 84 151 3.6E-5 T 28-03-2018 CIG75_RS17920 6fe518fd416f08165b063fac727cf9a0 159 Gene3D G3DSA:3.40.630.30 4 83 1.3E-7 T 28-03-2018 CIG75_RS11450 b4373f5f567c0ed243293a730252e469 220 SUPERFAMILY SSF56112 32 181 4.02E-17 T 28-03-2018 IPR011009 Protein kinase-like domain CIG75_RS11450 b4373f5f567c0ed243293a730252e469 220 Gene3D G3DSA:1.10.510.10 94 186 9.0E-5 T 28-03-2018 CIG75_RS11450 b4373f5f567c0ed243293a730252e469 220 Gene3D G3DSA:3.30.200.20 25 93 7.9E-5 T 28-03-2018 CIG75_RS15825 09997b33366b5f6f6954db50e1bf8c3e 417 Pfam PF07690 Major Facilitator Superfamily 16 348 4.6E-34 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CIG75_RS15825 09997b33366b5f6f6954db50e1bf8c3e 417 Gene3D G3DSA:1.20.1250.20 194 397 3.8E-22 T 28-03-2018 CIG75_RS15825 09997b33366b5f6f6954db50e1bf8c3e 417 SUPERFAMILY SSF103473 9 390 1.7E-46 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS15825 09997b33366b5f6f6954db50e1bf8c3e 417 Gene3D G3DSA:1.20.1250.20 2 188 4.3E-21 T 28-03-2018 CIG75_RS02560 3fd8be40686c940029588c52b67c2dbf 333 SUPERFAMILY SSF53807 52 331 2.9E-49 T 28-03-2018 CIG75_RS02560 3fd8be40686c940029588c52b67c2dbf 333 Gene3D G3DSA:3.40.50.1980 39 168 2.8E-28 T 28-03-2018 CIG75_RS02560 3fd8be40686c940029588c52b67c2dbf 333 Gene3D G3DSA:3.40.50.1980 169 333 1.2E-40 T 28-03-2018 CIG75_RS02560 3fd8be40686c940029588c52b67c2dbf 333 Pfam PF01497 Periplasmic binding protein 66 305 8.0E-32 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CIG75_RS14020 f60626e397246cbde4704d072b7f9e84 521 Pfam PF03793 PASTA domain 461 521 1.9E-12 T 28-03-2018 IPR005543 PASTA domain CIG75_RS14020 f60626e397246cbde4704d072b7f9e84 521 Pfam PF03793 PASTA domain 367 432 1.8E-9 T 28-03-2018 IPR005543 PASTA domain CIG75_RS14020 f60626e397246cbde4704d072b7f9e84 521 SMART SM00740 456 521 8.1E-10 T 28-03-2018 IPR005543 PASTA domain CIG75_RS14020 f60626e397246cbde4704d072b7f9e84 521 SMART SM00740 362 433 4.1E-8 T 28-03-2018 IPR005543 PASTA domain CIG75_RS14020 f60626e397246cbde4704d072b7f9e84 521 Gene3D G3DSA:1.10.510.10 184 462 0.01 T 28-03-2018 CIG75_RS14020 f60626e397246cbde4704d072b7f9e84 521 SMART SM00220 31 257 3.2E-6 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CIG75_RS14020 f60626e397246cbde4704d072b7f9e84 521 Gene3D G3DSA:3.30.200.20 15 93 1.3E-9 T 28-03-2018 CIG75_RS14020 f60626e397246cbde4704d072b7f9e84 521 Gene3D G3DSA:1.10.510.10 94 174 1.8E-12 T 28-03-2018 CIG75_RS14020 f60626e397246cbde4704d072b7f9e84 521 Pfam PF00069 Protein kinase domain 38 170 8.3E-12 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CIG75_RS14020 f60626e397246cbde4704d072b7f9e84 521 SUPERFAMILY SSF56112 28 213 2.16E-24 T 28-03-2018 IPR011009 Protein kinase-like domain CIG75_RS14020 f60626e397246cbde4704d072b7f9e84 521 SUPERFAMILY SSF54184 462 520 9.42E-6 T 28-03-2018 CIG75_RS17640 5c56082b026969280c5ba13c853bf2c2 641 Pfam PF04055 Radical SAM superfamily 302 460 1.3E-7 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CIG75_RS17640 5c56082b026969280c5ba13c853bf2c2 641 SUPERFAMILY SSF102114 273 520 7.46E-23 T 28-03-2018 CIG75_RS17640 5c56082b026969280c5ba13c853bf2c2 641 Pfam PF02310 B12 binding domain 131 238 6.2E-7 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CIG75_RS17640 5c56082b026969280c5ba13c853bf2c2 641 SMART SM00729 294 508 3.6E-8 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CIG75_RS17640 5c56082b026969280c5ba13c853bf2c2 641 Gene3D G3DSA:3.40.50.280 17 244 4.7E-7 T 28-03-2018 CIG75_RS17640 5c56082b026969280c5ba13c853bf2c2 641 Gene3D G3DSA:3.20.20.70 290 568 2.0E-22 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CIG75_RS05620 213138c243bd4b547a6de6d659622c06 226 TIGRFAM TIGR02840 spore_YtaF: putative sporulation protein YtaF 6 224 7.9E-64 T 28-03-2018 IPR014205 Sporulation protein YtaF CIG75_RS05620 213138c243bd4b547a6de6d659622c06 226 Pfam PF02659 Putative manganese efflux pump 3 80 4.4E-9 T 28-03-2018 IPR003810 Putative manganese efflux pump CIG75_RS05620 213138c243bd4b547a6de6d659622c06 226 Pfam PF02659 Putative manganese efflux pump 141 222 1.3E-8 T 28-03-2018 IPR003810 Putative manganese efflux pump CIG75_RS15225 f9ced0f82a424f5d203ac2fda6aa5ba7 179 Pfam PF06941 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) 1 166 3.8E-46 T 28-03-2018 IPR010708 5'(3')-deoxyribonucleotidase GO:0008253|GO:0009264 Reactome: R-HSA-73621 CIG75_RS15225 f9ced0f82a424f5d203ac2fda6aa5ba7 179 SUPERFAMILY SSF56784 1 166 4.13E-27 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS15225 f9ced0f82a424f5d203ac2fda6aa5ba7 179 Gene3D G3DSA:1.10.40.40 9 49 1.8E-10 T 28-03-2018 CIG75_RS15225 f9ced0f82a424f5d203ac2fda6aa5ba7 179 Gene3D G3DSA:3.40.50.1000 50 171 1.5E-27 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS00710 eb709a3bee15920bfb30f4f58c41cb2c 200 Gene3D G3DSA:3.40.50.150 4 192 3.7E-23 T 28-03-2018 CIG75_RS00710 eb709a3bee15920bfb30f4f58c41cb2c 200 Pfam PF13489 Methyltransferase domain 25 162 5.2E-17 T 28-03-2018 CIG75_RS00710 eb709a3bee15920bfb30f4f58c41cb2c 200 SUPERFAMILY SSF53335 5 186 2.92E-28 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CIG75_RS06405 3e96f2437fa7d7b0ca9dfd519770d0ac 170 Pfam PF00156 Phosphoribosyl transferase domain 45 149 1.5E-15 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CIG75_RS06405 3e96f2437fa7d7b0ca9dfd519770d0ac 170 TIGRFAM TIGR01090 apt: adenine phosphoribosyltransferase 4 170 1.1E-69 T 28-03-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 CIG75_RS06405 3e96f2437fa7d7b0ca9dfd519770d0ac 170 SUPERFAMILY SSF53271 2 164 3.67E-50 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CIG75_RS06405 3e96f2437fa7d7b0ca9dfd519770d0ac 170 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 3 170 38.338 T 28-03-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 CIG75_RS06405 3e96f2437fa7d7b0ca9dfd519770d0ac 170 Gene3D G3DSA:3.40.50.2020 1 170 3.3E-40 T 28-03-2018 CIG75_RS06720 2e922273ef41694eedfa4fd90c6a8fb6 1484 SUPERFAMILY SSF55048 686 741 1.83E-8 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CIG75_RS06720 2e922273ef41694eedfa4fd90c6a8fb6 1484 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 537 853 4.1E-92 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CIG75_RS06720 2e922273ef41694eedfa4fd90c6a8fb6 1484 Pfam PF08659 KR domain 1146 1309 5.5E-28 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS06720 2e922273ef41694eedfa4fd90c6a8fb6 1484 Gene3D G3DSA:3.40.47.10 4 272 1.9E-66 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS06720 2e922273ef41694eedfa4fd90c6a8fb6 1484 SMART SM00823 Phosphopantetheine attachment site 1396 1465 0.0015 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS06720 2e922273ef41694eedfa4fd90c6a8fb6 1484 Gene3D G3DSA:3.30.70.250 695 738 7.8E-14 T 28-03-2018 CIG75_RS06720 2e922273ef41694eedfa4fd90c6a8fb6 1484 Gene3D G3DSA:3.40.50.720 1136 1390 2.4E-24 T 28-03-2018 CIG75_RS06720 2e922273ef41694eedfa4fd90c6a8fb6 1484 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1420 1435 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS06720 2e922273ef41694eedfa4fd90c6a8fb6 1484 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1146 1327 3.9E-9 T 28-03-2018 CIG75_RS06720 2e922273ef41694eedfa4fd90c6a8fb6 1484 Pfam PF00698 Acyl transferase domain 536 834 3.5E-43 T 28-03-2018 IPR014043 Acyl transferase CIG75_RS06720 2e922273ef41694eedfa4fd90c6a8fb6 1484 SUPERFAMILY SSF51735 1142 1319 3.23E-20 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS06720 2e922273ef41694eedfa4fd90c6a8fb6 1484 Gene3D G3DSA:3.40.366.10 533 694 5.1E-37 T 28-03-2018 CIG75_RS06720 2e922273ef41694eedfa4fd90c6a8fb6 1484 Gene3D G3DSA:3.40.47.10 275 438 3.9E-55 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS06720 2e922273ef41694eedfa4fd90c6a8fb6 1484 SUPERFAMILY SSF53901 415 436 5.77E-83 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS06720 2e922273ef41694eedfa4fd90c6a8fb6 1484 SUPERFAMILY SSF53901 10 128 5.77E-83 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS06720 2e922273ef41694eedfa4fd90c6a8fb6 1484 SUPERFAMILY SSF53901 157 379 5.77E-83 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS06720 2e922273ef41694eedfa4fd90c6a8fb6 1484 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 268 386 1.0E-39 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CIG75_RS06720 2e922273ef41694eedfa4fd90c6a8fb6 1484 SUPERFAMILY SSF51735 929 1129 2.52E-18 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS06720 2e922273ef41694eedfa4fd90c6a8fb6 1484 SMART SM00825 Beta-ketoacyl synthase 13 440 3.3E-181 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CIG75_RS06720 2e922273ef41694eedfa4fd90c6a8fb6 1484 Gene3D G3DSA:3.40.366.10 739 861 5.9E-26 T 28-03-2018 CIG75_RS06720 2e922273ef41694eedfa4fd90c6a8fb6 1484 Gene3D G3DSA:1.10.1200.10 1391 1471 2.0E-21 T 28-03-2018 CIG75_RS06720 2e922273ef41694eedfa4fd90c6a8fb6 1484 Pfam PF00550 Phosphopantetheine attachment site 1399 1458 1.2E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS06720 2e922273ef41694eedfa4fd90c6a8fb6 1484 SUPERFAMILY SSF47336 1388 1461 4.97E-20 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS06720 2e922273ef41694eedfa4fd90c6a8fb6 1484 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 389 499 1.2E-22 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CIG75_RS06720 2e922273ef41694eedfa4fd90c6a8fb6 1484 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 12 260 4.5E-67 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CIG75_RS06720 2e922273ef41694eedfa4fd90c6a8fb6 1484 SUPERFAMILY SSF52151 615 688 1.23E-61 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CIG75_RS06720 2e922273ef41694eedfa4fd90c6a8fb6 1484 SUPERFAMILY SSF52151 748 844 1.23E-61 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CIG75_RS06720 2e922273ef41694eedfa4fd90c6a8fb6 1484 SUPERFAMILY SSF52151 534 587 1.23E-61 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CIG75_RS19015 69c82abbb0ca2ea5724c4fca4d0bcdf0 207 Gene3D G3DSA:1.20.1170.10 2 205 3.5E-5 T 28-03-2018 CIG75_RS19015 69c82abbb0ca2ea5724c4fca4d0bcdf0 207 Pfam PF06810 Phage minor structural protein GP20 26 159 1.5E-34 T 28-03-2018 IPR009636 Capsid assembly scaffolding protein GO:0019069|GO:0046806 CIG75_RS15695 07beefcc399c3d985b24823dde58d533 524 SUPERFAMILY SSF51338 481 523 5.04E-22 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CIG75_RS15695 07beefcc399c3d985b24823dde58d533 524 SUPERFAMILY SSF51338 2 61 5.04E-22 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CIG75_RS15695 07beefcc399c3d985b24823dde58d533 524 Gene3D G3DSA:2.30.40.10 2 112 8.5E-22 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CIG75_RS15695 07beefcc399c3d985b24823dde58d533 524 Gene3D G3DSA:3.20.20.140 181 479 6.1E-53 T 28-03-2018 CIG75_RS15695 07beefcc399c3d985b24823dde58d533 524 Pfam PF07969 Amidohydrolase family 49 522 7.7E-115 T 28-03-2018 IPR013108 Amidohydrolase 3 CIG75_RS15695 07beefcc399c3d985b24823dde58d533 524 SUPERFAMILY SSF51556 193 482 3.53E-33 T 28-03-2018 IPR032466 Metal-dependent hydrolase CIG75_RS15695 07beefcc399c3d985b24823dde58d533 524 SUPERFAMILY SSF51556 60 117 3.53E-33 T 28-03-2018 IPR032466 Metal-dependent hydrolase CIG75_RS19030 30e7a2dd6de0d0206ee5effc2b73aa01 540 Pfam PF04233 Phage Mu protein F like protein 198 303 1.1E-17 T 28-03-2018 IPR006528 Phage head morphogenesis domain CIG75_RS19030 30e7a2dd6de0d0206ee5effc2b73aa01 540 TIGRFAM TIGR01641 phageSPP1_gp7: phage head morphogenesis protein, SPP1 gp7 family 200 307 6.1E-27 T 28-03-2018 IPR006528 Phage head morphogenesis domain CIG75_RS16365 d9bf35fc0911e41eba58f3473220e327 386 Gene3D G3DSA:2.60.120.10 222 360 6.5E-33 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CIG75_RS16365 d9bf35fc0911e41eba58f3473220e327 386 SUPERFAMILY SSF51182 8 383 1.4E-94 T 28-03-2018 IPR011051 RmlC-like cupin domain CIG75_RS16365 d9bf35fc0911e41eba58f3473220e327 386 Pfam PF04209 homogentisate 1,2-dioxygenase 106 382 7.2E-21 T 28-03-2018 IPR005708 Homogentisate 1,2-dioxygenase GO:0004411|GO:0006559|GO:0006570|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|Reactome: R-HSA-71182 CIG75_RS16365 d9bf35fc0911e41eba58f3473220e327 386 Gene3D G3DSA:2.60.120.10 65 176 1.9E-9 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CIG75_RS20305 adc8587f5c5168e4eb26c444b9e0d10e 126 Gene3D G3DSA:3.30.1330.40 1 126 6.0E-51 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CIG75_RS20305 adc8587f5c5168e4eb26c444b9e0d10e 126 SUPERFAMILY SSF55298 1 125 8.48E-49 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CIG75_RS20305 adc8587f5c5168e4eb26c444b9e0d10e 126 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 101 119 - T 28-03-2018 IPR019897 RidA, conserved site CIG75_RS20305 adc8587f5c5168e4eb26c444b9e0d10e 126 Pfam PF01042 Endoribonuclease L-PSP 9 124 9.5E-47 T 28-03-2018 IPR006175 YjgF/YER057c/UK114 family CIG75_RS20305 adc8587f5c5168e4eb26c444b9e0d10e 126 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 3 124 5.7E-55 T 28-03-2018 IPR006056 RidA family CIG75_RS02285 a28c8af60a4db4598a0f3686b30972ae 189 Pfam PF14117 Domain of unknown function (DUF4287) 9 64 3.5E-10 T 28-03-2018 IPR025629 Protein of unknown function DUF4287 CIG75_RS07190 84fb5482a0d87377a0697bb9cd036cd1 393 Pfam PF00108 Thiolase, N-terminal domain 4 263 2.9E-90 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CIG75_RS07190 84fb5482a0d87377a0697bb9cd036cd1 393 SUPERFAMILY SSF53901 3 269 1.85E-82 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS07190 84fb5482a0d87377a0697bb9cd036cd1 393 Pfam PF02803 Thiolase, C-terminal domain 271 392 5.4E-45 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CIG75_RS07190 84fb5482a0d87377a0697bb9cd036cd1 393 PIRSF PIRSF000429 1 393 8.0E-137 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CIG75_RS07190 84fb5482a0d87377a0697bb9cd036cd1 393 ProSitePatterns PS00099 Thiolases active site. 374 387 - T 28-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 CIG75_RS07190 84fb5482a0d87377a0697bb9cd036cd1 393 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 391 8.5E-147 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CIG75_RS07190 84fb5482a0d87377a0697bb9cd036cd1 393 Gene3D G3DSA:3.40.47.10 1 271 6.7E-61 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS07190 84fb5482a0d87377a0697bb9cd036cd1 393 Gene3D G3DSA:3.40.47.10 272 390 9.7E-31 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS07190 84fb5482a0d87377a0697bb9cd036cd1 393 SUPERFAMILY SSF53901 271 392 5.27E-42 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS11540 77a745f5de39c7a3fcbd0b94a209f0f4 247 SUPERFAMILY SSF56281 3 247 3.8E-50 T 28-03-2018 IPR001279 Metallo-beta-lactamase CIG75_RS11540 77a745f5de39c7a3fcbd0b94a209f0f4 247 Pfam PF12706 Beta-lactamase superfamily domain 32 215 4.0E-20 T 28-03-2018 IPR001279 Metallo-beta-lactamase CIG75_RS11540 77a745f5de39c7a3fcbd0b94a209f0f4 247 Gene3D G3DSA:3.60.15.10 2 247 9.3E-47 T 28-03-2018 IPR001279 Metallo-beta-lactamase CIG75_RS11540 77a745f5de39c7a3fcbd0b94a209f0f4 247 SMART SM00849 20 192 1.6E-7 T 28-03-2018 IPR001279 Metallo-beta-lactamase CIG75_RS14795 bfcc601cd5b91534cf487f64def7a3a4 247 SUPERFAMILY SSF75217 73 244 3.45E-52 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CIG75_RS14795 bfcc601cd5b91534cf487f64def7a3a4 247 Pfam PF04452 RNA methyltransferase 16 238 1.8E-72 T 28-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CIG75_RS14795 bfcc601cd5b91534cf487f64def7a3a4 247 SUPERFAMILY SSF88697 2 68 2.98E-17 T 28-03-2018 IPR015947 PUA-like domain CIG75_RS14795 bfcc601cd5b91534cf487f64def7a3a4 247 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 3 244 2.3E-57 T 28-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CIG75_RS14795 bfcc601cd5b91534cf487f64def7a3a4 247 PIRSF PIRSF015601 1 245 3.0E-63 T 28-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CIG75_RS14795 bfcc601cd5b91534cf487f64def7a3a4 247 Gene3D G3DSA:3.40.1280.10 1 246 2.7E-82 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CIG75_RS07155 0e26a40b719262d3525bcf631c81eb10 71 PRINTS PR00352 3Fe-4S ferredoxin signature 55 67 8.1E-7 T 28-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CIG75_RS07155 0e26a40b719262d3525bcf631c81eb10 71 PRINTS PR00352 3Fe-4S ferredoxin signature 6 17 8.1E-7 T 28-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CIG75_RS07155 0e26a40b719262d3525bcf631c81eb10 71 PRINTS PR00352 3Fe-4S ferredoxin signature 17 27 8.1E-7 T 28-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CIG75_RS07155 0e26a40b719262d3525bcf631c81eb10 71 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 6 69 1.5E-17 T 28-03-2018 CIG75_RS07155 0e26a40b719262d3525bcf631c81eb10 71 SUPERFAMILY SSF54862 3 71 3.59E-11 T 28-03-2018 CIG75_RS07155 0e26a40b719262d3525bcf631c81eb10 71 Gene3D G3DSA:3.30.70.20 1 71 9.9E-8 T 28-03-2018 CIG75_RS01505 5924c22f93b82b4f3829fb38201724e6 514 Gene3D G3DSA:1.10.390.10 363 514 4.1E-48 T 28-03-2018 CIG75_RS01505 5924c22f93b82b4f3829fb38201724e6 514 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 214 358 3.2E-48 T 28-03-2018 IPR013856 Peptidase M4 domain GO:0004222 CIG75_RS01505 5924c22f93b82b4f3829fb38201724e6 514 Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif 77 125 5.5E-16 T 28-03-2018 IPR011096 FTP domain CIG75_RS01505 5924c22f93b82b4f3829fb38201724e6 514 Gene3D G3DSA:3.10.170.10 212 362 4.1E-51 T 28-03-2018 CIG75_RS01505 5924c22f93b82b4f3829fb38201724e6 514 SUPERFAMILY SSF55486 212 513 8.06E-95 T 28-03-2018 CIG75_RS01505 5924c22f93b82b4f3829fb38201724e6 514 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 349 365 1.1E-27 T 28-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 CIG75_RS01505 5924c22f93b82b4f3829fb38201724e6 514 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 313 333 1.1E-27 T 28-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 CIG75_RS01505 5924c22f93b82b4f3829fb38201724e6 514 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 370 381 1.1E-27 T 28-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 CIG75_RS01505 5924c22f93b82b4f3829fb38201724e6 514 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 437 453 1.1E-27 T 28-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 CIG75_RS01505 5924c22f93b82b4f3829fb38201724e6 514 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 361 513 2.9E-43 T 28-03-2018 IPR001570 Peptidase M4, C-terminal GO:0004222 CIG75_RS12640 c36606b3e1d56efa14debeb001b041a5 227 SUPERFAMILY SSF51206 7 147 9.17E-36 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like CIG75_RS12640 c36606b3e1d56efa14debeb001b041a5 227 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 193 208 1.5E-5 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CIG75_RS12640 c36606b3e1d56efa14debeb001b041a5 227 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 177 193 1.5E-5 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CIG75_RS12640 c36606b3e1d56efa14debeb001b041a5 227 SMART SM00100 14 135 7.8E-20 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CIG75_RS12640 c36606b3e1d56efa14debeb001b041a5 227 Gene3D G3DSA:1.10.10.10 148 227 4.6E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS12640 c36606b3e1d56efa14debeb001b041a5 227 SUPERFAMILY SSF46785 149 226 4.63E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS12640 c36606b3e1d56efa14debeb001b041a5 227 Pfam PF00027 Cyclic nucleotide-binding domain 34 120 2.1E-21 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CIG75_RS12640 c36606b3e1d56efa14debeb001b041a5 227 Pfam PF13545 Crp-like helix-turn-helix domain 153 225 2.5E-17 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CIG75_RS12640 c36606b3e1d56efa14debeb001b041a5 227 Gene3D G3DSA:2.60.120.10 6 147 2.7E-34 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CIG75_RS12640 c36606b3e1d56efa14debeb001b041a5 227 SMART SM00419 171 219 1.9E-11 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CIG75_RS00230 d7aecdf43ece06ac18d0fe7710d17567 139 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 8 96 1.0E-19 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CIG75_RS00230 d7aecdf43ece06ac18d0fe7710d17567 139 Gene3D G3DSA:3.30.230.10 1 118 2.2E-38 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CIG75_RS00230 d7aecdf43ece06ac18d0fe7710d17567 139 SUPERFAMILY SSF54211 1 109 1.26E-34 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CIG75_RS00230 d7aecdf43ece06ac18d0fe7710d17567 139 ProSitePatterns PS00648 Bacterial ribonuclease P protein component signature. 52 66 - T 28-03-2018 IPR020539 Ribonuclease P, conserved site GO:0004526 CIG75_RS00230 d7aecdf43ece06ac18d0fe7710d17567 139 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 2 112 20.761 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CIG75_RS00230 d7aecdf43ece06ac18d0fe7710d17567 139 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 3 109 8.6E-31 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CIG75_RS00230 d7aecdf43ece06ac18d0fe7710d17567 139 Pfam PF00825 Ribonuclease P 2 109 1.3E-37 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CIG75_RS02060 b229bc2ba1f6227c5bba6ca0ea36fdb1 170 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 1 157 6.3E-33 T 28-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 CIG75_RS02060 b229bc2ba1f6227c5bba6ca0ea36fdb1 170 Pfam PF01066 CDP-alcohol phosphatidyltransferase 2 69 2.0E-15 T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CIG75_RS02060 b229bc2ba1f6227c5bba6ca0ea36fdb1 170 PIRSF PIRSF000847 1 167 1.4E-39 T 28-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 CIG75_RS02060 b229bc2ba1f6227c5bba6ca0ea36fdb1 170 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 47 69 - T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CIG75_RS02890 cd7d54c3dbc3d9098b38db872c420c36 130 Gene3D G3DSA:3.10.20.30 46 129 9.1E-17 T 28-03-2018 IPR012675 Beta-grasp domain CIG75_RS02890 cd7d54c3dbc3d9098b38db872c420c36 130 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 54 127 1.2E-10 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CIG75_RS02890 cd7d54c3dbc3d9098b38db872c420c36 130 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 82 90 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CIG75_RS02890 cd7d54c3dbc3d9098b38db872c420c36 130 SUPERFAMILY SSF54292 48 127 9.57E-17 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CIG75_RS11355 a7b751599d3fc293445702efcef34a1d 133 SMART SM00851 14 107 8.4E-21 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CIG75_RS11355 a7b751599d3fc293445702efcef34a1d 133 TIGRFAM TIGR00160 MGSA: methylglyoxal synthase 2 120 3.6E-58 T 28-03-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 CIG75_RS11355 a7b751599d3fc293445702efcef34a1d 133 Hamap MF_00549 Methylglyoxal synthase [mgsA]. 1 120 35.431 T 28-03-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 CIG75_RS11355 a7b751599d3fc293445702efcef34a1d 133 ProSitePatterns PS01335 Methylglyoxal synthase active site. 54 62 - T 28-03-2018 IPR018148 Methylglyoxal synthase, active site GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 CIG75_RS11355 a7b751599d3fc293445702efcef34a1d 133 SUPERFAMILY SSF52335 1 128 3.53E-51 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CIG75_RS11355 a7b751599d3fc293445702efcef34a1d 133 PIRSF PIRSF006614 1 133 4.8E-58 T 28-03-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 CIG75_RS11355 a7b751599d3fc293445702efcef34a1d 133 Gene3D G3DSA:3.40.50.1380 1 133 2.9E-34 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CIG75_RS11355 a7b751599d3fc293445702efcef34a1d 133 Pfam PF02142 MGS-like domain 15 107 3.7E-15 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CIG75_RS09620 39937d92be3e68abb84f583eb673f63a 74 SUPERFAMILY SSF51219 3 70 7.06E-33 T 28-03-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain CIG75_RS09620 39937d92be3e68abb84f583eb673f63a 74 PRINTS PR00687 Tryptophan RNA-binding attenuator protein signature 54 70 5.5E-29 T 28-03-2018 IPR000824 Transcription attenuation protein MtrB GO:0003723|GO:0006353|GO:0006355 CIG75_RS09620 39937d92be3e68abb84f583eb673f63a 74 PRINTS PR00687 Tryptophan RNA-binding attenuator protein signature 5 22 5.5E-29 T 28-03-2018 IPR000824 Transcription attenuation protein MtrB GO:0003723|GO:0006353|GO:0006355 CIG75_RS09620 39937d92be3e68abb84f583eb673f63a 74 PRINTS PR00687 Tryptophan RNA-binding attenuator protein signature 38 54 5.5E-29 T 28-03-2018 IPR000824 Transcription attenuation protein MtrB GO:0003723|GO:0006353|GO:0006355 CIG75_RS09620 39937d92be3e68abb84f583eb673f63a 74 PRINTS PR00687 Tryptophan RNA-binding attenuator protein signature 22 38 5.5E-29 T 28-03-2018 IPR000824 Transcription attenuation protein MtrB GO:0003723|GO:0006353|GO:0006355 CIG75_RS09620 39937d92be3e68abb84f583eb673f63a 74 Gene3D G3DSA:2.60.40.50 4 69 2.2E-38 T 28-03-2018 IPR023558 Tryptophan RNA-binding attenuator protein domain CIG75_RS09620 39937d92be3e68abb84f583eb673f63a 74 Pfam PF02081 Tryptophan RNA-binding attenuator protein 2 68 1.1E-38 T 28-03-2018 IPR023558 Tryptophan RNA-binding attenuator protein domain CIG75_RS11890 3d3fcf247715f3c8a5b93ae94a6d250d 216 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 93 216 9.5E-42 T 28-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CIG75_RS11890 3d3fcf247715f3c8a5b93ae94a6d250d 216 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 94 2.9E-41 T 28-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CIG75_RS11890 3d3fcf247715f3c8a5b93ae94a6d250d 216 SUPERFAMILY SSF54713 56 197 9.55E-57 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CIG75_RS11890 3d3fcf247715f3c8a5b93ae94a6d250d 216 Gene3D G3DSA:1.10.8.10 1 55 1.2E-25 T 28-03-2018 CIG75_RS11890 3d3fcf247715f3c8a5b93ae94a6d250d 216 Pfam PF00889 Elongation factor TS 72 98 8.9E-9 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CIG75_RS11890 3d3fcf247715f3c8a5b93ae94a6d250d 216 Pfam PF00889 Elongation factor TS 92 197 6.5E-37 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CIG75_RS11890 3d3fcf247715f3c8a5b93ae94a6d250d 216 SUPERFAMILY SSF46934 3 54 8.23E-21 T 28-03-2018 IPR009060 UBA-like GO:0005515 CIG75_RS11890 3d3fcf247715f3c8a5b93ae94a6d250d 216 Hamap MF_00050 Elongation factor Ts [tsf]. 1 214 56.435 T 28-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CIG75_RS11890 3d3fcf247715f3c8a5b93ae94a6d250d 216 Gene3D G3DSA:1.10.286.20 122 141 1.7E-21 T 28-03-2018 CIG75_RS11890 3d3fcf247715f3c8a5b93ae94a6d250d 216 ProSitePatterns PS01126 Elongation factor Ts signature 1. 11 26 - T 28-03-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CIG75_RS11890 3d3fcf247715f3c8a5b93ae94a6d250d 216 ProSitePatterns PS01127 Elongation factor Ts signature 2. 76 86 - T 28-03-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CIG75_RS11890 3d3fcf247715f3c8a5b93ae94a6d250d 216 Gene3D G3DSA:3.30.479.20 142 196 2.3E-19 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CIG75_RS11890 3d3fcf247715f3c8a5b93ae94a6d250d 216 Gene3D G3DSA:3.30.479.20 60 121 3.5E-15 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CIG75_RS18645 7ada5d2ca03de1e37711f17e4151742d 420 Gene3D G3DSA:3.90.600.10 327 419 1.1E-33 T 28-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CIG75_RS18645 7ada5d2ca03de1e37711f17e4151742d 420 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 419 1.7E-164 T 28-03-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CIG75_RS18645 7ada5d2ca03de1e37711f17e4151742d 420 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 101 293 8.3E-74 T 28-03-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CIG75_RS18645 7ada5d2ca03de1e37711f17e4151742d 420 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 287 294 - T 28-03-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CIG75_RS18645 7ada5d2ca03de1e37711f17e4151742d 420 Gene3D G3DSA:3.30.1490.20 85 187 2.8E-20 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CIG75_RS18645 7ada5d2ca03de1e37711f17e4151742d 420 SMART SM01210 327 419 2.3E-47 T 28-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CIG75_RS18645 7ada5d2ca03de1e37711f17e4151742d 420 Gene3D G3DSA:3.40.50.20 2 84 1.7E-36 T 28-03-2018 CIG75_RS18645 7ada5d2ca03de1e37711f17e4151742d 420 SUPERFAMILY SSF52440 1 101 4.6E-34 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CIG75_RS18645 7ada5d2ca03de1e37711f17e4151742d 420 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 328 416 1.9E-29 T 28-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CIG75_RS18645 7ada5d2ca03de1e37711f17e4151742d 420 SMART SM01209 101 293 1.4E-120 T 28-03-2018 CIG75_RS18645 7ada5d2ca03de1e37711f17e4151742d 420 SUPERFAMILY SSF56059 102 317 1.66E-57 T 28-03-2018 CIG75_RS18645 7ada5d2ca03de1e37711f17e4151742d 420 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 419 41.678 T 28-03-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CIG75_RS18645 7ada5d2ca03de1e37711f17e4151742d 420 SUPERFAMILY SSF51246 325 419 4.45E-29 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CIG75_RS18645 7ada5d2ca03de1e37711f17e4151742d 420 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 100 2.7E-32 T 28-03-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CIG75_RS18645 7ada5d2ca03de1e37711f17e4151742d 420 Gene3D G3DSA:3.30.470.20 189 326 1.1E-57 T 28-03-2018 CIG75_RS12100 c622da5a98969a6b7c3e9d9e1575a1b1 297 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 6 88 5.5E-18 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CIG75_RS12100 c622da5a98969a6b7c3e9d9e1575a1b1 297 Gene3D G3DSA:1.10.443.10 109 291 7.1E-46 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CIG75_RS12100 c622da5a98969a6b7c3e9d9e1575a1b1 297 SUPERFAMILY SSF56349 6 290 5.3E-58 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CIG75_RS12100 c622da5a98969a6b7c3e9d9e1575a1b1 297 Gene3D G3DSA:1.10.150.130 1 108 1.1E-23 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CIG75_RS12100 c622da5a98969a6b7c3e9d9e1575a1b1 297 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 4 297 57.058 T 28-03-2018 IPR023009 Tyrosine recombinase XerC/XerD CIG75_RS12100 c622da5a98969a6b7c3e9d9e1575a1b1 297 Pfam PF00589 Phage integrase family 110 282 1.0E-47 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CIG75_RS12100 c622da5a98969a6b7c3e9d9e1575a1b1 297 TIGRFAM TIGR02224 recomb_XerC: tyrosine recombinase XerC 8 297 8.3E-104 T 28-03-2018 IPR011931 Tyrosine recombinase XerC GO:0003677|GO:0006310|GO:0007049|GO:0007059|GO:0015074|GO:0051301 CIG75_RS08480 0f60c628a1288195c822407976890bf9 372 Gene3D G3DSA:3.40.630.10 1 372 4.8E-66 T 28-03-2018 CIG75_RS08480 0f60c628a1288195c822407976890bf9 372 SUPERFAMILY SSF55031 181 288 1.96E-19 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CIG75_RS08480 0f60c628a1288195c822407976890bf9 372 Pfam PF01546 Peptidase family M20/M25/M40 75 368 7.9E-18 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CIG75_RS08480 0f60c628a1288195c822407976890bf9 372 SUPERFAMILY SSF53187 290 368 7.04E-59 T 28-03-2018 CIG75_RS08480 0f60c628a1288195c822407976890bf9 372 SUPERFAMILY SSF53187 7 178 7.04E-59 T 28-03-2018 CIG75_RS08480 0f60c628a1288195c822407976890bf9 372 PIRSF PIRSF001123 6 84 6.5E-4 T 28-03-2018 IPR008007 Peptidase M42 CIG75_RS08480 0f60c628a1288195c822407976890bf9 372 PIRSF PIRSF001123 95 215 7.5E-5 T 28-03-2018 IPR008007 Peptidase M42 CIG75_RS08480 0f60c628a1288195c822407976890bf9 372 PIRSF PIRSF001123 250 372 1.8E-4 T 28-03-2018 IPR008007 Peptidase M42 CIG75_RS08480 0f60c628a1288195c822407976890bf9 372 TIGRFAM TIGR01883 PepT-like: peptidase T-like protein 8 369 1.5E-118 T 28-03-2018 IPR010162 Peptidase M20B, peptidase T-like CIG75_RS08480 0f60c628a1288195c822407976890bf9 372 Pfam PF07687 Peptidase dimerisation domain 184 275 4.5E-14 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CIG75_RS16135 29b030c5ac824a5971435a578fb073e3 264 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS16135 29b030c5ac824a5971435a578fb073e3 264 SUPERFAMILY SSF52540 5 216 5.79E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS16135 29b030c5ac824a5971435a578fb073e3 264 Gene3D G3DSA:3.40.50.300 1 220 1.7E-53 T 28-03-2018 CIG75_RS16135 29b030c5ac824a5971435a578fb073e3 264 Pfam PF00005 ABC transporter 24 158 9.7E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS16135 29b030c5ac824a5971435a578fb073e3 264 SMART SM00382 33 205 2.2E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS17055 cf9980d139e1e5d1188ecc9c1237d344 79 Pfam PF03840 Preprotein translocase SecG subunit 7 74 6.9E-19 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CIG75_RS17055 cf9980d139e1e5d1188ecc9c1237d344 79 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 4 75 5.4E-18 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CIG75_RS17055 cf9980d139e1e5d1188ecc9c1237d344 79 PRINTS PR01651 Protein-export SecG membrane protein signature 24 38 2.6E-9 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CIG75_RS17055 cf9980d139e1e5d1188ecc9c1237d344 79 PRINTS PR01651 Protein-export SecG membrane protein signature 4 24 2.6E-9 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CIG75_RS17055 cf9980d139e1e5d1188ecc9c1237d344 79 PRINTS PR01651 Protein-export SecG membrane protein signature 56 78 2.6E-9 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CIG75_RS02545 bafd4d83e53f058e28182ac1adf990eb 328 Pfam PF01032 FecCD transport family 2 318 7.4E-99 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CIG75_RS02545 bafd4d83e53f058e28182ac1adf990eb 328 Gene3D G3DSA:1.10.3470.10 1 322 2.2E-78 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CIG75_RS02545 bafd4d83e53f058e28182ac1adf990eb 328 SUPERFAMILY SSF81345 6 319 1.7E-83 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CIG75_RS08120 4b201f55b39b9f95973b6e3a62bdafd9 111 Pfam PF04327 Cysteine protease Prp 1 105 1.2E-24 T 28-03-2018 IPR007422 Cysteine protease Prp CIG75_RS08120 4b201f55b39b9f95973b6e3a62bdafd9 111 Gene3D G3DSA:3.30.70.1490 1 111 3.5E-28 T 28-03-2018 IPR007422 Cysteine protease Prp CIG75_RS08120 4b201f55b39b9f95973b6e3a62bdafd9 111 SUPERFAMILY SSF118010 1 109 1.83E-26 T 28-03-2018 IPR007422 Cysteine protease Prp CIG75_RS03335 96aea8c2a9ec6ef7fd996621057a45e4 151 Pfam PF02310 B12 binding domain 18 109 8.1E-14 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CIG75_RS03335 96aea8c2a9ec6ef7fd996621057a45e4 151 SUPERFAMILY SSF52242 15 147 1.15E-35 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CIG75_RS03335 96aea8c2a9ec6ef7fd996621057a45e4 151 TIGRFAM TIGR01501 MthylAspMutase: methylaspartate mutase, S subunit 16 147 1.9E-66 T 28-03-2018 IPR006394 Glutamate mutase sigma subunit GO:0016866|GO:0019670 KEGG: 00630+5.4.99.1|KEGG: 00660+5.4.99.1|MetaCyc: PWY-5087|MetaCyc: PWY-5103|MetaCyc: PWY-6728 CIG75_RS03335 96aea8c2a9ec6ef7fd996621057a45e4 151 Gene3D G3DSA:3.40.50.280 8 150 1.2E-29 T 28-03-2018 CIG75_RS03335 96aea8c2a9ec6ef7fd996621057a45e4 151 Hamap MF_00526 Glutamate mutase sigma subunit [glmS]. 14 150 39.483 T 28-03-2018 IPR006394 Glutamate mutase sigma subunit GO:0016866|GO:0019670 KEGG: 00630+5.4.99.1|KEGG: 00660+5.4.99.1|MetaCyc: PWY-5087|MetaCyc: PWY-5103|MetaCyc: PWY-6728 CIG75_RS16845 aea3a127af64a4aaa020a50a3a4a7c51 320 Gene3D G3DSA:3.40.50.1980 30 158 2.0E-28 T 28-03-2018 CIG75_RS16845 aea3a127af64a4aaa020a50a3a4a7c51 320 SUPERFAMILY SSF53807 45 314 1.32E-66 T 28-03-2018 CIG75_RS16845 aea3a127af64a4aaa020a50a3a4a7c51 320 Gene3D G3DSA:3.40.50.1980 159 320 1.2E-29 T 28-03-2018 CIG75_RS16845 aea3a127af64a4aaa020a50a3a4a7c51 320 Pfam PF01497 Periplasmic binding protein 62 292 5.4E-31 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CIG75_RS15330 0d1b7f45efefd51787c597a4a10a536f 660 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 431 610 9.6E-33 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CIG75_RS15330 0d1b7f45efefd51787c597a4a10a536f 660 Gene3D G3DSA:1.10.287.950 122 412 6.2E-5 T 28-03-2018 CIG75_RS15330 0d1b7f45efefd51787c597a4a10a536f 660 Gene3D G3DSA:1.10.287.950 413 646 1.6E-41 T 28-03-2018 CIG75_RS15330 0d1b7f45efefd51787c597a4a10a536f 660 Pfam PF00672 HAMP domain 299 351 1.6E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CIG75_RS15330 0d1b7f45efefd51787c597a4a10a536f 660 SUPERFAMILY SSF58104 390 659 6.41E-56 T 28-03-2018 CIG75_RS15330 0d1b7f45efefd51787c597a4a10a536f 660 SUPERFAMILY SSF58104 330 357 6.41E-56 T 28-03-2018 CIG75_RS15330 0d1b7f45efefd51787c597a4a10a536f 660 Pfam PF05228 CHASE4 domain 61 195 1.0E-13 T 28-03-2018 IPR007892 CHASE4 CIG75_RS15330 0d1b7f45efefd51787c597a4a10a536f 660 SMART SM00304 297 355 8.9E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CIG75_RS15330 0d1b7f45efefd51787c597a4a10a536f 660 SMART SM00283 363 659 2.0E-33 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CIG75_RS17085 0d785e6b38579c818be621c6222f32a6 327 Gene3D G3DSA:3.40.50.1360 71 324 2.4E-37 T 28-03-2018 CIG75_RS17085 0d785e6b38579c818be621c6222f32a6 327 Pfam PF04198 Putative sugar-binding domain 73 318 1.6E-67 T 28-03-2018 IPR007324 Sugar-binding domain, putative GO:0030246 CIG75_RS17085 0d785e6b38579c818be621c6222f32a6 327 SUPERFAMILY SSF46785 2 67 4.29E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS17085 0d785e6b38579c818be621c6222f32a6 327 SUPERFAMILY SSF100950 79 318 1.0E-63 T 28-03-2018 CIG75_RS17085 0d785e6b38579c818be621c6222f32a6 327 Gene3D G3DSA:1.10.10.10 1 70 1.5E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS16215 447c7f1fe57f5fefab7d3ccff439cd7e 294 Gene3D G3DSA:3.30.565.10 145 293 7.1E-44 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS16215 447c7f1fe57f5fefab7d3ccff439cd7e 294 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 187 291 7.9E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS16215 447c7f1fe57f5fefab7d3ccff439cd7e 294 Gene3D G3DSA:1.10.287.130 62 140 6.1E-14 T 28-03-2018 CIG75_RS16215 447c7f1fe57f5fefab7d3ccff439cd7e 294 SUPERFAMILY SSF55874 135 291 3.14E-43 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS16215 447c7f1fe57f5fefab7d3ccff439cd7e 294 SMART SM00388 78 144 1.2E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CIG75_RS16215 447c7f1fe57f5fefab7d3ccff439cd7e 294 PRINTS PR00344 Bacterial sensor protein C-terminal signature 242 252 1.5E-20 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS16215 447c7f1fe57f5fefab7d3ccff439cd7e 294 PRINTS PR00344 Bacterial sensor protein C-terminal signature 224 238 1.5E-20 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS16215 447c7f1fe57f5fefab7d3ccff439cd7e 294 PRINTS PR00344 Bacterial sensor protein C-terminal signature 277 290 1.5E-20 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS16215 447c7f1fe57f5fefab7d3ccff439cd7e 294 PRINTS PR00344 Bacterial sensor protein C-terminal signature 253 271 1.5E-20 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS16215 447c7f1fe57f5fefab7d3ccff439cd7e 294 SUPERFAMILY SSF47384 70 143 3.73E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CIG75_RS16215 447c7f1fe57f5fefab7d3ccff439cd7e 294 Pfam PF00512 His Kinase A (phospho-acceptor) domain 80 143 1.6E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CIG75_RS16215 447c7f1fe57f5fefab7d3ccff439cd7e 294 SMART SM00387 186 293 3.7E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS08415 40090ec911aa130e2f18418e37539a24 331 Gene3D G3DSA:3.40.50.970 4 331 2.4E-82 T 28-03-2018 CIG75_RS08415 40090ec911aa130e2f18418e37539a24 331 SUPERFAMILY SSF52518 3 330 3.82E-100 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CIG75_RS08415 40090ec911aa130e2f18418e37539a24 331 Pfam PF00676 Dehydrogenase E1 component 22 320 2.7E-93 T 28-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 CIG75_RS17415 cd5f8b85ba14db0d662b33eb1b27c2ce 294 Pfam PF02687 FtsX-like permease family 200 293 4.4E-7 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CIG75_RS17415 cd5f8b85ba14db0d662b33eb1b27c2ce 294 PIRSF PIRSF003097 1 294 3.1E-86 T 28-03-2018 IPR004513 Cell division protein FtsX GO:0007049|GO:0016021 CIG75_RS11125 5cecc53f79835e171c65eda9dc7a4189 293 TIGRFAM TIGR02320 PEP_mutase: phosphoenolpyruvate mutase 7 276 1.3E-97 T 28-03-2018 IPR012698 Phosphoenolpyruvate phosphomutase, core GO:0050188 KEGG: 00440+5.4.2.9|MetaCyc: PWY-5757|MetaCyc: PWY-6322|MetaCyc: PWY-6682|MetaCyc: PWY-6839|MetaCyc: PWY-7419|MetaCyc: PWY-7510|MetaCyc: PWY-7769 CIG75_RS11125 5cecc53f79835e171c65eda9dc7a4189 293 Pfam PF13714 Phosphoenolpyruvate phosphomutase 7 252 8.2E-69 T 28-03-2018 CIG75_RS11125 5cecc53f79835e171c65eda9dc7a4189 293 SUPERFAMILY SSF51621 2 288 2.92E-81 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CIG75_RS11125 5cecc53f79835e171c65eda9dc7a4189 293 Gene3D G3DSA:3.20.20.60 1 290 9.7E-78 T 28-03-2018 CIG75_RS18795 d2f1c2370394c5e02e0f55e647d0b23d 189 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 3 182 4.5E-45 T 28-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase CIG75_RS18795 d2f1c2370394c5e02e0f55e647d0b23d 189 Gene3D G3DSA:3.40.50.10420 1 189 5.7E-61 T 28-03-2018 CIG75_RS18795 d2f1c2370394c5e02e0f55e647d0b23d 189 SUPERFAMILY SSF100950 1 187 4.05E-54 T 28-03-2018 CIG75_RS18795 d2f1c2370394c5e02e0f55e647d0b23d 189 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 3 182 4.6E-51 T 28-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase CIG75_RS18795 d2f1c2370394c5e02e0f55e647d0b23d 189 PIRSF PIRSF006806 1 185 1.3E-48 T 28-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase CIG75_RS16475 6488d9147e104e44fe505ba8233fd442 254 Gene3D G3DSA:3.40.50.620 1 254 1.2E-68 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CIG75_RS16475 6488d9147e104e44fe505ba8233fd442 254 Pfam PF01012 Electron transfer flavoprotein domain 23 198 3.8E-47 T 28-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CIG75_RS16475 6488d9147e104e44fe505ba8233fd442 254 ProSitePatterns PS01065 Electron transfer flavoprotein beta-subunit signature. 153 173 - T 28-03-2018 IPR000049 Electron transfer flavoprotein, beta-subunit, conserved site GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 CIG75_RS16475 6488d9147e104e44fe505ba8233fd442 254 PIRSF PIRSF000090 1 254 9.7E-74 T 28-03-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 CIG75_RS16475 6488d9147e104e44fe505ba8233fd442 254 SMART SM00893 21 209 3.7E-55 T 28-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CIG75_RS16475 6488d9147e104e44fe505ba8233fd442 254 SUPERFAMILY SSF52402 1 248 6.58E-72 T 28-03-2018 CIG75_RS04145 cbdd181ca1c5f21a20549900733bc9f1 635 Pfam PF09823 Domain of unknown function (DUF2357) 130 387 1.7E-66 T 28-03-2018 IPR018633 Domain of unknown function DUF2357 CIG75_RS04145 cbdd181ca1c5f21a20549900733bc9f1 635 Pfam PF04411 PD-(D/E)XK nuclease superfamily 410 570 1.4E-44 T 28-03-2018 IPR007505 PD-(D/E)XK nuclease superfamily 7 CIG75_RS10855 c0f5582bcba06e28c361e4978c2cb356 490 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 198 218 - T 28-03-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 CIG75_RS10855 c0f5582bcba06e28c361e4978c2cb356 490 Pfam PF00919 Uncharacterized protein family UPF0004 50 150 1.7E-27 T 28-03-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 CIG75_RS10855 c0f5582bcba06e28c361e4978c2cb356 490 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 50 481 1.8E-155 T 28-03-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 CIG75_RS10855 c0f5582bcba06e28c361e4978c2cb356 490 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 48 485 72.021 T 28-03-2018 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 CIG75_RS10855 c0f5582bcba06e28c361e4978c2cb356 490 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 50 483 1.9E-170 T 28-03-2018 CIG75_RS10855 c0f5582bcba06e28c361e4978c2cb356 490 Pfam PF04055 Radical SAM superfamily 198 368 3.4E-33 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CIG75_RS10855 c0f5582bcba06e28c361e4978c2cb356 490 Pfam PF01938 TRAM domain 423 484 9.3E-13 T 28-03-2018 IPR002792 TRAM domain CIG75_RS10855 c0f5582bcba06e28c361e4978c2cb356 490 Gene3D G3DSA:3.80.30.20 191 425 5.7E-57 T 28-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe CIG75_RS10855 c0f5582bcba06e28c361e4978c2cb356 490 SUPERFAMILY SSF102114 182 420 2.35E-63 T 28-03-2018 CIG75_RS10855 c0f5582bcba06e28c361e4978c2cb356 490 SMART SM00729 194 411 2.8E-61 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CIG75_RS06260 f6f8d69cf914d8dbc221e255b44a89ed 222 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 36 221 9.5E-24 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CIG75_RS06260 f6f8d69cf914d8dbc221e255b44a89ed 222 SUPERFAMILY SSF161098 11 211 8.5E-48 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CIG75_RS06260 f6f8d69cf914d8dbc221e255b44a89ed 222 Gene3D G3DSA:1.10.3720.10 7 222 2.6E-39 T 28-03-2018 CIG75_RS15980 ab6eb2bb492efbae5838c10b352a259b 463 SUPERFAMILY SSF102114 24 431 4.32E-69 T 28-03-2018 CIG75_RS15980 ab6eb2bb492efbae5838c10b352a259b 463 Pfam PF04055 Radical SAM superfamily 63 232 1.0E-16 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CIG75_RS15980 ab6eb2bb492efbae5838c10b352a259b 463 SMART SM00729 57 278 1.7E-34 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CIG75_RS15980 ab6eb2bb492efbae5838c10b352a259b 463 Gene3D G3DSA:3.20.20.70 29 362 3.9E-30 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CIG75_RS15925 598e0fe168fdb37442f1356e8cf1d39d 218 PIRSF PIRSF000370 1 217 5.2E-61 T 28-03-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 CIG75_RS15925 598e0fe168fdb37442f1356e8cf1d39d 218 Gene3D G3DSA:3.20.20.70 22 215 5.6E-22 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CIG75_RS15925 598e0fe168fdb37442f1356e8cf1d39d 218 SUPERFAMILY SSF102114 26 108 1.2E-17 T 28-03-2018 CIG75_RS15925 598e0fe168fdb37442f1356e8cf1d39d 218 Pfam PF04055 Radical SAM superfamily 24 188 1.2E-15 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CIG75_RS15925 598e0fe168fdb37442f1356e8cf1d39d 218 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 1 214 35.621 T 28-03-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 CIG75_RS15925 598e0fe168fdb37442f1356e8cf1d39d 218 Pfam PF13394 4Fe-4S single cluster domain 22 118 1.9E-13 T 28-03-2018 CIG75_RS15570 b3c9f7e148935d0b43fdc467933f51e5 296 Gene3D G3DSA:2.30.260.10 220 295 4.1E-17 T 28-03-2018 CIG75_RS15570 b3c9f7e148935d0b43fdc467933f51e5 296 Gene3D G3DSA:3.90.1720.10 80 219 3.2E-18 T 28-03-2018 CIG75_RS15570 b3c9f7e148935d0b43fdc467933f51e5 296 SUPERFAMILY SSF54001 174 293 3.6E-41 T 28-03-2018 CIG75_RS15570 b3c9f7e148935d0b43fdc467933f51e5 296 Pfam PF00877 NlpC/P60 family 188 289 3.7E-30 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CIG75_RS03035 8675b00d7fc2204da8084a17f791533e 547 ProSitePatterns PS00216 Sugar transport proteins signature 1. 75 91 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CIG75_RS03035 8675b00d7fc2204da8084a17f791533e 547 Pfam PF07690 Major Facilitator Superfamily 26 417 4.5E-54 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CIG75_RS03035 8675b00d7fc2204da8084a17f791533e 547 SUPERFAMILY SSF103473 497 522 6.02E-75 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS03035 8675b00d7fc2204da8084a17f791533e 547 SUPERFAMILY SSF103473 8 204 6.02E-75 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS03035 8675b00d7fc2204da8084a17f791533e 547 SUPERFAMILY SSF103473 256 427 6.02E-75 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS03035 8675b00d7fc2204da8084a17f791533e 547 Gene3D G3DSA:1.20.1250.20 16 203 1.4E-34 T 28-03-2018 CIG75_RS03035 8675b00d7fc2204da8084a17f791533e 547 PRINTS PR01036 Tetracycline resistance protein TetB signature 408 427 6.8E-8 T 28-03-2018 CIG75_RS03035 8675b00d7fc2204da8084a17f791533e 547 PRINTS PR01036 Tetracycline resistance protein TetB signature 115 135 6.8E-8 T 28-03-2018 CIG75_RS03035 8675b00d7fc2204da8084a17f791533e 547 PRINTS PR01036 Tetracycline resistance protein TetB signature 25 49 6.8E-8 T 28-03-2018 CIG75_RS03035 8675b00d7fc2204da8084a17f791533e 547 PRINTS PR01036 Tetracycline resistance protein TetB signature 210 228 6.8E-8 T 28-03-2018 CIG75_RS03035 8675b00d7fc2204da8084a17f791533e 547 PRINTS PR01036 Tetracycline resistance protein TetB signature 145 169 6.8E-8 T 28-03-2018 CIG75_RS03035 8675b00d7fc2204da8084a17f791533e 547 Gene3D G3DSA:1.20.1250.20 260 538 2.2E-33 T 28-03-2018 CIG75_RS03035 8675b00d7fc2204da8084a17f791533e 547 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 22 519 7.7E-83 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CIG75_RS19965 59e539fc019cc861d3249d052ee522e9 132 SMART SM00345 19 78 4.1E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CIG75_RS19965 59e539fc019cc861d3249d052ee522e9 132 Gene3D G3DSA:1.10.10.10 3 80 2.2E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS19965 59e539fc019cc861d3249d052ee522e9 132 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 78 1.0E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CIG75_RS19965 59e539fc019cc861d3249d052ee522e9 132 SUPERFAMILY SSF46785 9 82 9.91E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS00350 f106f45f43d3cd864f93ac8fc615a142 162 Gene3D G3DSA:1.20.5.1070 14 56 3.4E-11 T 28-03-2018 CIG75_RS00350 f106f45f43d3cd864f93ac8fc615a142 162 Gene3D G3DSA:1.20.5.340 112 156 0.016 T 28-03-2018 CIG75_RS00350 f106f45f43d3cd864f93ac8fc615a142 162 Gene3D G3DSA:3.90.20.10 57 111 2.6E-8 T 28-03-2018 CIG75_RS00350 f106f45f43d3cd864f93ac8fc615a142 162 SUPERFAMILY SSF57997 6 151 1.96E-6 T 28-03-2018 CIG75_RS00350 f106f45f43d3cd864f93ac8fc615a142 162 Gene3D G3DSA:1.20.5.440 3 13 0.39 T 28-03-2018 CIG75_RS05810 891f6bbf0f61621aa9869a3765451e16 622 Pfam PF01935 Domain of unknown function DUF87 175 336 6.4E-15 T 28-03-2018 IPR002789 Helicase HerA, central domain CIG75_RS05810 891f6bbf0f61621aa9869a3765451e16 622 Gene3D G3DSA:3.40.50.300 34 521 1.0E-28 T 28-03-2018 CIG75_RS05810 891f6bbf0f61621aa9869a3765451e16 622 SUPERFAMILY SSF52540 160 526 2.47E-33 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS04700 ff6c452f7d2f47e6e97763cd890cde1f 147 Pfam PF01844 HNH endonuclease 41 81 1.1E-6 T 28-03-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 CIG75_RS04700 ff6c452f7d2f47e6e97763cd890cde1f 147 SMART SM00507 28 77 1.6E-7 T 28-03-2018 IPR003615 HNH nuclease CIG75_RS04700 ff6c452f7d2f47e6e97763cd890cde1f 147 Gene3D G3DSA:3.40.1800.10 11 94 1.4E-13 T 28-03-2018 CIG75_RS06510 7796b2d0cf30a0644bc6c94c153e34e8 264 SMART SM00382 31 233 1.1E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS06510 7796b2d0cf30a0644bc6c94c153e34e8 264 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS06510 7796b2d0cf30a0644bc6c94c153e34e8 264 Gene3D G3DSA:3.40.50.300 1 250 1.4E-56 T 28-03-2018 CIG75_RS06510 7796b2d0cf30a0644bc6c94c153e34e8 264 Pfam PF00005 ABC transporter 22 177 7.2E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS06510 7796b2d0cf30a0644bc6c94c153e34e8 264 SUPERFAMILY SSF52540 2 235 6.85E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS03695 3297f85274703de3af4543207653856e 171 Gene3D G3DSA:3.40.30.10 22 171 6.6E-38 T 28-03-2018 CIG75_RS03695 3297f85274703de3af4543207653856e 171 Pfam PF00578 AhpC/TSA family 35 151 3.6E-28 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CIG75_RS03695 3297f85274703de3af4543207653856e 171 ProSitePatterns PS00194 Thioredoxin family active site. 62 80 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 CIG75_RS03695 3297f85274703de3af4543207653856e 171 SUPERFAMILY SSF52833 31 170 4.33E-41 T 28-03-2018 IPR012336 Thioredoxin-like fold CIG75_RS04635 65a2bfaecd9adc3b4dcf84e54dd8aacb 294 Gene3D G3DSA:2.60.40.10 199 289 1.5E-4 T 28-03-2018 IPR013783 Immunoglobulin-like fold CIG75_RS04635 65a2bfaecd9adc3b4dcf84e54dd8aacb 294 Pfam PF12801 4Fe-4S binding domain 130 165 4.7E-4 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CIG75_RS04635 65a2bfaecd9adc3b4dcf84e54dd8aacb 294 Pfam PF12801 4Fe-4S binding domain 48 87 1.1E-9 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CIG75_RS16950 199787b76af5701f36c5e2016e847072 587 TIGRFAM TIGR01466 cobJ_cbiH: precorrin-3B C17-methyltransferase 5 247 1.3E-98 T 28-03-2018 IPR006363 Precorrin-3B C17-methyltransferase domain GO:0008168|GO:0009236 CIG75_RS16950 199787b76af5701f36c5e2016e847072 587 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 465 565 9.9E-7 T 28-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CIG75_RS16950 199787b76af5701f36c5e2016e847072 587 Gene3D G3DSA:3.30.413.10 376 569 2.6E-19 T 28-03-2018 CIG75_RS16950 199787b76af5701f36c5e2016e847072 587 SUPERFAMILY SSF53790 1 257 7.72E-58 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CIG75_RS16950 199787b76af5701f36c5e2016e847072 587 SUPERFAMILY SSF56014 450 565 4.19E-21 T 28-03-2018 CIG75_RS16950 199787b76af5701f36c5e2016e847072 587 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 4 215 2.3E-38 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CIG75_RS16950 199787b76af5701f36c5e2016e847072 587 Gene3D G3DSA:3.30.950.10 128 245 3.9E-51 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CIG75_RS16950 199787b76af5701f36c5e2016e847072 587 Gene3D G3DSA:3.40.1010.10 2 127 2.0E-34 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CIG75_RS13775 2a3d0008444fd79928d5b936d258a993 538 Gene3D G3DSA:1.10.260.40 38 149 0.027 T 28-03-2018 CIG75_RS13775 2a3d0008444fd79928d5b936d258a993 538 Gene3D G3DSA:3.40.1800.10 407 505 1.2E-6 T 28-03-2018 CIG75_RS06455 d9e3af06ece5afeacdc186a12a20d29b 150 Gene3D G3DSA:3.30.530.20 13 150 2.9E-19 T 28-03-2018 IPR023393 START-like domain CIG75_RS06455 d9e3af06ece5afeacdc186a12a20d29b 150 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 25 145 1.4E-18 T 28-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CIG75_RS06455 d9e3af06ece5afeacdc186a12a20d29b 150 SUPERFAMILY SSF55961 18 144 2.65E-24 T 28-03-2018 CIG75_RS04765 5ae3dfa6202cb5a0bfc3bb43781f1008 349 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 62 312 3.1E-53 T 28-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 CIG75_RS04765 5ae3dfa6202cb5a0bfc3bb43781f1008 349 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 20 320 33.599 T 28-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 CIG75_RS04765 5ae3dfa6202cb5a0bfc3bb43781f1008 349 Gene3D G3DSA:3.40.50.300 96 256 1.0E-24 T 28-03-2018 CIG75_RS04765 5ae3dfa6202cb5a0bfc3bb43781f1008 349 Pfam PF03193 RsgA GTPase 82 257 5.0E-50 T 28-03-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 CIG75_RS04765 5ae3dfa6202cb5a0bfc3bb43781f1008 349 Gene3D G3DSA:1.10.40.50 259 325 2.9E-20 T 28-03-2018 CIG75_RS04765 5ae3dfa6202cb5a0bfc3bb43781f1008 349 Gene3D G3DSA:2.40.50.140 14 83 3.8E-8 T 28-03-2018 CIG75_RS04765 5ae3dfa6202cb5a0bfc3bb43781f1008 349 SUPERFAMILY SSF52540 99 318 1.17E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS07285 4cc1a2add2530464da3460556e1e1735 676 SUPERFAMILY SSF52540 61 224 4.56E-5 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS07285 4cc1a2add2530464da3460556e1e1735 676 Pfam PF10593 Z1 domain 292 497 5.2E-45 T 28-03-2018 IPR018310 Putative endonuclease, Z1 domain CIG75_RS07285 4cc1a2add2530464da3460556e1e1735 676 Gene3D G3DSA:3.40.50.300 26 227 5.9E-5 T 28-03-2018 CIG75_RS14175 e856bdf2e7025602674fa239163aeb81 355 Pfam PF01757 Acyltransferase family 4 328 2.0E-38 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 CIG75_RS09130 0f25f7fbb01236af9ef9402af9b2b795 809 Gene3D G3DSA:3.40.710.10 255 649 2.8E-93 T 28-03-2018 CIG75_RS09130 0f25f7fbb01236af9ef9402af9b2b795 809 Pfam PF00912 Transglycosylase 54 227 1.8E-58 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 CIG75_RS09130 0f25f7fbb01236af9ef9402af9b2b795 809 Pfam PF00905 Penicillin binding protein transpeptidase domain 330 610 1.7E-38 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CIG75_RS09130 0f25f7fbb01236af9ef9402af9b2b795 809 SUPERFAMILY SSF56601 209 231 4.83E-105 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CIG75_RS09130 0f25f7fbb01236af9ef9402af9b2b795 809 SUPERFAMILY SSF56601 266 624 4.83E-105 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CIG75_RS09130 0f25f7fbb01236af9ef9402af9b2b795 809 Gene3D G3DSA:1.10.3810.10 43 244 1.6E-71 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 CIG75_RS09130 0f25f7fbb01236af9ef9402af9b2b795 809 Gene3D G3DSA:2.60.40.10 650 748 2.1E-6 T 28-03-2018 IPR013783 Immunoglobulin-like fold CIG75_RS09130 0f25f7fbb01236af9ef9402af9b2b795 809 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 65 615 1.7E-166 T 28-03-2018 CIG75_RS09130 0f25f7fbb01236af9ef9402af9b2b795 809 SUPERFAMILY SSF53955 43 250 4.78E-70 T 28-03-2018 IPR023346 Lysozyme-like domain CIG75_RS08305 c41a21a3f62e667fcd22ba5ded1e475c 242 Gene3D G3DSA:3.20.20.370 30 242 4.4E-45 T 28-03-2018 CIG75_RS08305 c41a21a3f62e667fcd22ba5ded1e475c 242 SUPERFAMILY SSF88713 37 237 1.66E-49 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CIG75_RS08305 c41a21a3f62e667fcd22ba5ded1e475c 242 Pfam PF01522 Polysaccharide deacetylase 44 153 4.5E-26 T 28-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CIG75_RS19110 fc36a87f090b69c28a289772c05405a7 133 Gene3D G3DSA:3.90.1150.10 1 121 3.2E-4 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CIG75_RS14585 1a630aae1ff686ca6f6c4acb161b239a 188 SUPERFAMILY SSF52317 1 180 1.02E-32 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CIG75_RS14585 1a630aae1ff686ca6f6c4acb161b239a 188 Gene3D G3DSA:3.40.50.880 1 187 9.6E-35 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CIG75_RS14585 1a630aae1ff686ca6f6c4acb161b239a 188 Pfam PF01965 DJ-1/PfpI family 1 167 6.0E-20 T 28-03-2018 IPR002818 DJ-1/PfpI CIG75_RS01390 a3ca99df575000259f31e17cc3a2eb7d 391 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 214 378 4.0E-32 T 28-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 CIG75_RS01390 a3ca99df575000259f31e17cc3a2eb7d 391 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 7 380 2.7E-82 T 28-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 CIG75_RS19515 2ed49947b1b604e5fb75fb34be82dbc1 185 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 100 1.9E-30 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CIG75_RS19515 2ed49947b1b604e5fb75fb34be82dbc1 185 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 3 94 8.1E-30 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CIG75_RS19515 2ed49947b1b604e5fb75fb34be82dbc1 185 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 127 179 8.2E-30 T 28-03-2018 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal CIG75_RS19515 2ed49947b1b604e5fb75fb34be82dbc1 185 Hamap MF_00839 Ribosome hibernation promoting factor [hpf]. 1 183 24.896 T 28-03-2018 IPR034694 Ribosome hibernation promoting factor, long/plastid CIG75_RS19515 2ed49947b1b604e5fb75fb34be82dbc1 185 SUPERFAMILY SSF69754 1 102 7.46E-32 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CIG75_RS19515 2ed49947b1b604e5fb75fb34be82dbc1 185 Gene3D G3DSA:3.30.160.100 1 98 9.0E-31 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CIG75_RS10955 9dc380721570f736c1189074a68644b0 374 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 178 365 6.8E-50 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CIG75_RS10955 9dc380721570f736c1189074a68644b0 374 SUPERFAMILY SSF53187 175 369 5.44E-51 T 28-03-2018 CIG75_RS10955 9dc380721570f736c1189074a68644b0 374 SMART SM00646 245 365 5.7E-37 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CIG75_RS10955 9dc380721570f736c1189074a68644b0 374 Gene3D G3DSA:3.40.630.40 172 374 3.4E-57 T 28-03-2018 CIG75_RS10265 e1a46cefb8e67b879ec14893244d7a68 456 SUPERFAMILY SSF51984 1 89 1.57E-21 T 28-03-2018 CIG75_RS10265 e1a46cefb8e67b879ec14893244d7a68 456 SUPERFAMILY SSF53244 302 444 1.32E-34 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CIG75_RS10265 e1a46cefb8e67b879ec14893244d7a68 456 Gene3D G3DSA:3.40.1190.10 92 303 1.5E-42 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CIG75_RS10265 e1a46cefb8e67b879ec14893244d7a68 456 Gene3D G3DSA:3.40.50.720 1 90 1.4E-10 T 28-03-2018 CIG75_RS10265 e1a46cefb8e67b879ec14893244d7a68 456 Pfam PF02875 Mur ligase family, glutamate ligase domain 304 385 2.9E-18 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CIG75_RS10265 e1a46cefb8e67b879ec14893244d7a68 456 SUPERFAMILY SSF53623 88 301 3.01E-56 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CIG75_RS10265 e1a46cefb8e67b879ec14893244d7a68 456 Gene3D G3DSA:3.90.190.20 304 456 7.1E-32 T 28-03-2018 CIG75_RS10265 e1a46cefb8e67b879ec14893244d7a68 456 Pfam PF01225 Mur ligase family, catalytic domain 3 99 6.0E-18 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CIG75_RS10265 e1a46cefb8e67b879ec14893244d7a68 456 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 3 444 3.1E-136 T 28-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CIG75_RS10265 e1a46cefb8e67b879ec14893244d7a68 456 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 1 452 36.27 T 28-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CIG75_RS10265 e1a46cefb8e67b879ec14893244d7a68 456 Pfam PF08245 Mur ligase middle domain 107 283 4.6E-25 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CIG75_RS10240 bfc444759b481464e809c9be7ee973b9 253 Gene3D G3DSA:3.40.50.1360 1 251 9.1E-78 T 28-03-2018 CIG75_RS10240 bfc444759b481464e809c9be7ee973b9 253 TIGRFAM TIGR00502 nagB: glucosamine-6-phosphate deaminase 2 243 1.4E-85 T 28-03-2018 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 CIG75_RS10240 bfc444759b481464e809c9be7ee973b9 253 SUPERFAMILY SSF100950 2 242 1.1E-89 T 28-03-2018 CIG75_RS10240 bfc444759b481464e809c9be7ee973b9 253 Hamap MF_01241 Glucosamine-6-phosphate deaminase [nagB]. 1 241 41.515 T 28-03-2018 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 CIG75_RS10240 bfc444759b481464e809c9be7ee973b9 253 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 12 224 4.8E-23 T 28-03-2018 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 CIG75_RS10240 bfc444759b481464e809c9be7ee973b9 253 ProSitePatterns PS01161 Glucosamine/galactosamine-6-phosphate isomerases signature. 120 138 - T 28-03-2018 IPR018321 Glucosamine-6-phosphate isomerase, conserved site GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 CIG75_RS07170 3b1912b4584142ef0dccdd6949df4972 322 Gene3D G3DSA:3.40.50.300 20 186 1.1E-28 T 28-03-2018 CIG75_RS07170 3b1912b4584142ef0dccdd6949df4972 322 Gene3D G3DSA:1.10.8.300 200 308 9.1E-33 T 28-03-2018 CIG75_RS07170 3b1912b4584142ef0dccdd6949df4972 322 SUPERFAMILY SSF52540 3 283 5.35E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS07170 3b1912b4584142ef0dccdd6949df4972 322 PIRSF PIRSF002849 1 313 1.7E-130 T 28-03-2018 CIG75_RS07170 3b1912b4584142ef0dccdd6949df4972 322 SMART SM00382 36 177 8.0E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS07170 3b1912b4584142ef0dccdd6949df4972 322 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 39 169 1.8E-62 T 28-03-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 CIG75_RS02615 3431e1de0dde51126a473aabc14bf702 298 SUPERFAMILY SSF53448 1 271 6.05E-67 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CIG75_RS02615 3431e1de0dde51126a473aabc14bf702 298 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 3 267 2.5E-117 T 28-03-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 CIG75_RS02615 3431e1de0dde51126a473aabc14bf702 298 Pfam PF00483 Nucleotidyl transferase 5 271 1.3E-31 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CIG75_RS02615 3431e1de0dde51126a473aabc14bf702 298 Gene3D G3DSA:3.90.550.10 1 294 1.8E-57 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CIG75_RS06520 3eacbb28190657f326977980c91804e9 230 Gene3D G3DSA:3.40.50.1860 1 117 6.2E-28 T 28-03-2018 CIG75_RS06520 3eacbb28190657f326977980c91804e9 230 Pfam PF01177 Asp/Glu/Hydantoin racemase 7 224 7.2E-56 T 28-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CIG75_RS06520 3eacbb28190657f326977980c91804e9 230 Gene3D G3DSA:3.40.50.1860 118 215 3.5E-24 T 28-03-2018 CIG75_RS06520 3eacbb28190657f326977980c91804e9 230 SUPERFAMILY SSF53681 1 116 9.16E-36 T 28-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CIG75_RS06520 3eacbb28190657f326977980c91804e9 230 TIGRFAM TIGR00035 asp_race: aspartate racemase 1 229 3.3E-73 T 28-03-2018 IPR004380 Aspartate racemase GO:0006520|GO:0016855 CIG75_RS06520 3eacbb28190657f326977980c91804e9 230 SUPERFAMILY SSF53681 119 229 5.72E-30 T 28-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CIG75_RS05470 85d93948ca44091ca2e8f9d278f3a79f 265 Pfam PF01940 Integral membrane protein DUF92 10 255 9.5E-68 T 28-03-2018 IPR002794 Protein of unknown function DUF92, TMEM19 GO:0016021 CIG75_RS06760 2f22854d3592b11b750148b733bee743 352 Pfam PF03576 Peptidase family S58 17 332 3.1E-115 T 28-03-2018 IPR005321 Peptidase S58, DmpA CIG75_RS06760 2f22854d3592b11b750148b733bee743 352 SUPERFAMILY SSF56266 1 332 4.97E-105 T 28-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CIG75_RS06760 2f22854d3592b11b750148b733bee743 352 Gene3D G3DSA:3.60.70.12 1 349 5.2E-112 T 28-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CIG75_RS08785 3656d187dfe3e338f10b41d8f847f213 492 Gene3D G3DSA:1.20.1250.20 247 492 6.6E-37 T 28-03-2018 CIG75_RS08785 3656d187dfe3e338f10b41d8f847f213 492 Gene3D G3DSA:1.20.1250.20 2 196 1.6E-38 T 28-03-2018 CIG75_RS08785 3656d187dfe3e338f10b41d8f847f213 492 SUPERFAMILY SSF103473 459 485 1.27E-75 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS08785 3656d187dfe3e338f10b41d8f847f213 492 SUPERFAMILY SSF103473 9 197 1.27E-75 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS08785 3656d187dfe3e338f10b41d8f847f213 492 SUPERFAMILY SSF103473 244 414 1.27E-75 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS08785 3656d187dfe3e338f10b41d8f847f213 492 Pfam PF07690 Major Facilitator Superfamily 14 404 3.6E-52 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CIG75_RS08785 3656d187dfe3e338f10b41d8f847f213 492 PRINTS PR01036 Tetracycline resistance protein TetB signature 102 122 2.3E-8 T 28-03-2018 CIG75_RS08785 3656d187dfe3e338f10b41d8f847f213 492 PRINTS PR01036 Tetracycline resistance protein TetB signature 332 352 2.3E-8 T 28-03-2018 CIG75_RS08785 3656d187dfe3e338f10b41d8f847f213 492 PRINTS PR01036 Tetracycline resistance protein TetB signature 395 414 2.3E-8 T 28-03-2018 CIG75_RS08785 3656d187dfe3e338f10b41d8f847f213 492 PRINTS PR01036 Tetracycline resistance protein TetB signature 12 36 2.3E-8 T 28-03-2018 CIG75_RS08785 3656d187dfe3e338f10b41d8f847f213 492 PRINTS PR01036 Tetracycline resistance protein TetB signature 132 156 2.3E-8 T 28-03-2018 CIG75_RS08785 3656d187dfe3e338f10b41d8f847f213 492 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 9 415 2.1E-73 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CIG75_RS03810 5165ecbce39a737ad1072400687c62c0 219 SUPERFAMILY SSF55469 11 213 3.4E-49 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CIG75_RS03810 5165ecbce39a737ad1072400687c62c0 219 Gene3D G3DSA:3.40.109.10 3 214 1.6E-43 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CIG75_RS03810 5165ecbce39a737ad1072400687c62c0 219 Pfam PF00881 Nitroreductase family 15 182 3.6E-30 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CIG75_RS03810 5165ecbce39a737ad1072400687c62c0 219 TIGRFAM TIGR02476 BluB: 5,6-dimethylbenzimidazole synthase 3 203 6.7E-70 T 28-03-2018 IPR012825 5,6-dimethylbenzimidazole synthase BluB KEGG: 00740+1.13.11.79|MetaCyc: PWY-5508|MetaCyc: PWY-5523 CIG75_RS04330 9b0634eb3afe8e7029c1a69ffcc4858a 401 Pfam PF00082 Subtilase family 158 386 2.8E-35 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CIG75_RS04330 9b0634eb3afe8e7029c1a69ffcc4858a 401 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 159 170 - T 28-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site CIG75_RS04330 9b0634eb3afe8e7029c1a69ffcc4858a 401 SUPERFAMILY SSF52743 135 396 1.06E-76 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CIG75_RS04330 9b0634eb3afe8e7029c1a69ffcc4858a 401 Gene3D G3DSA:3.40.50.200 97 401 1.2E-79 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CIG75_RS04330 9b0634eb3afe8e7029c1a69ffcc4858a 401 PRINTS PR00723 Subtilisin serine protease family (S8) signature 192 205 7.2E-11 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CIG75_RS04330 9b0634eb3afe8e7029c1a69ffcc4858a 401 PRINTS PR00723 Subtilisin serine protease family (S8) signature 347 363 7.2E-11 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CIG75_RS04330 9b0634eb3afe8e7029c1a69ffcc4858a 401 PRINTS PR00723 Subtilisin serine protease family (S8) signature 154 173 7.2E-11 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CIG75_RS03240 ba894f9358fda187197a5ad9b6210790 153 Gene3D G3DSA:2.60.40.10 51 152 5.5E-12 T 28-03-2018 IPR013783 Immunoglobulin-like fold CIG75_RS03240 ba894f9358fda187197a5ad9b6210790 153 Pfam PF13115 YtkA-like 56 135 7.4E-16 T 28-03-2018 IPR032693 YtkA-like domain CIG75_RS03240 ba894f9358fda187197a5ad9b6210790 153 SUPERFAMILY SSF49373 58 141 7.59E-7 T 28-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments CIG75_RS08590 71ccf378dfe538b11a4d7a6d07ac218f 380 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 18 251 5.6E-76 T 28-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 CIG75_RS08590 71ccf378dfe538b11a4d7a6d07ac218f 380 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 107 124 1.5E-15 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CIG75_RS08590 71ccf378dfe538b11a4d7a6d07ac218f 380 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 134 147 1.5E-15 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CIG75_RS08590 71ccf378dfe538b11a4d7a6d07ac218f 380 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 54 65 1.5E-15 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CIG75_RS08590 71ccf378dfe538b11a4d7a6d07ac218f 380 SUPERFAMILY SSF56601 20 271 2.96E-73 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CIG75_RS08590 71ccf378dfe538b11a4d7a6d07ac218f 380 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 271 361 1.3E-13 T 28-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CIG75_RS08590 71ccf378dfe538b11a4d7a6d07ac218f 380 Gene3D G3DSA:2.60.410.10 272 361 1.6E-17 T 28-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CIG75_RS08590 71ccf378dfe538b11a4d7a6d07ac218f 380 SUPERFAMILY SSF69189 271 363 1.04E-15 T 28-03-2018 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CIG75_RS08590 71ccf378dfe538b11a4d7a6d07ac218f 380 Gene3D G3DSA:3.40.710.10 6 271 1.9E-45 T 28-03-2018 CIG75_RS08590 71ccf378dfe538b11a4d7a6d07ac218f 380 SMART SM00936 271 361 8.3E-18 T 28-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CIG75_RS19630 c7b2cd18a336ea0609ad2453d7bad105 216 Hamap MF_00235 Adenylate kinase [adk]. 1 213 52.753 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CIG75_RS19630 c7b2cd18a336ea0609ad2453d7bad105 216 TIGRFAM TIGR01351 adk: adenylate kinase 2 212 1.3E-80 T 28-03-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 CIG75_RS19630 c7b2cd18a336ea0609ad2453d7bad105 216 Gene3D G3DSA:3.40.50.300 1 216 2.4E-65 T 28-03-2018 CIG75_RS19630 c7b2cd18a336ea0609ad2453d7bad105 216 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 28-03-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CIG75_RS19630 c7b2cd18a336ea0609ad2453d7bad105 216 Pfam PF05191 Adenylate kinase, active site lid 127 162 3.4E-18 T 28-03-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 CIG75_RS19630 c7b2cd18a336ea0609ad2453d7bad105 216 SUPERFAMILY SSF52540 1 213 5.43E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS19630 c7b2cd18a336ea0609ad2453d7bad105 216 PRINTS PR00094 Adenylate kinase signature 4 17 2.1E-32 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CIG75_RS19630 c7b2cd18a336ea0609ad2453d7bad105 216 PRINTS PR00094 Adenylate kinase signature 160 175 2.1E-32 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CIG75_RS19630 c7b2cd18a336ea0609ad2453d7bad105 216 PRINTS PR00094 Adenylate kinase signature 32 46 2.1E-32 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CIG75_RS19630 c7b2cd18a336ea0609ad2453d7bad105 216 PRINTS PR00094 Adenylate kinase signature 177 191 2.1E-32 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CIG75_RS19630 c7b2cd18a336ea0609ad2453d7bad105 216 PRINTS PR00094 Adenylate kinase signature 81 97 2.1E-32 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CIG75_RS19630 c7b2cd18a336ea0609ad2453d7bad105 216 Pfam PF00406 Adenylate kinase 6 190 1.9E-56 T 28-03-2018 CIG75_RS18845 cd0197749212251ae3425dd2a518e157 303 Pfam PF02628 Cytochrome oxidase assembly protein 53 288 8.1E-31 T 28-03-2018 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 CIG75_RS06705 40acd2607cf83956c99d09bfce1fbd77 360 Pfam PF03845 Spore germination protein 10 301 1.5E-31 T 28-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 CIG75_RS06705 40acd2607cf83956c99d09bfce1fbd77 360 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 6 357 5.9E-60 T 28-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 CIG75_RS11140 f9f0269de843a67db7b0cd2db55c4ed4 91 Gene3D G3DSA:1.10.260.40 17 91 3.4E-9 T 28-03-2018 CIG75_RS11140 f9f0269de843a67db7b0cd2db55c4ed4 91 SUPERFAMILY SSF47413 14 81 8.44E-9 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CIG75_RS11140 f9f0269de843a67db7b0cd2db55c4ed4 91 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 20 79 9.3E-6 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS03135 b9592f05ddea3ebca4c27f6b9b47d0b2 240 Gene3D G3DSA:3.10.350.10 170 230 5.7E-18 T 28-03-2018 CIG75_RS03135 b9592f05ddea3ebca4c27f6b9b47d0b2 240 Pfam PF01476 LysM domain 176 225 5.6E-12 T 28-03-2018 IPR018392 LysM domain CIG75_RS03135 b9592f05ddea3ebca4c27f6b9b47d0b2 240 SUPERFAMILY SSF54106 174 225 2.35E-7 T 28-03-2018 IPR018392 LysM domain CIG75_RS03135 b9592f05ddea3ebca4c27f6b9b47d0b2 240 SMART SM00257 175 225 1.0E-8 T 28-03-2018 IPR018392 LysM domain CIG75_RS14760 d2cbccbe29121e948e11b76892108f2b 452 Pfam PF00574 Clp protease 38 115 3.9E-6 T 28-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA CIG75_RS14760 d2cbccbe29121e948e11b76892108f2b 452 SUPERFAMILY SSF52096 24 200 5.58E-26 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CIG75_RS14760 d2cbccbe29121e948e11b76892108f2b 452 Pfam PF01957 NfeD-like C-terminal, partner-binding 288 436 1.5E-17 T 28-03-2018 IPR002810 NfeD-like, C-terminal domain CIG75_RS14760 d2cbccbe29121e948e11b76892108f2b 452 Gene3D G3DSA:3.90.226.10 24 209 5.0E-25 T 28-03-2018 CIG75_RS14760 d2cbccbe29121e948e11b76892108f2b 452 Gene3D G3DSA:2.40.50.140 376 445 2.3E-7 T 28-03-2018 CIG75_RS00120 205c4b10b3a656c0a4ef93a8c532e378 214 SUPERFAMILY SSF52540 1 206 9.28E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS00120 205c4b10b3a656c0a4ef93a8c532e378 214 Gene3D G3DSA:3.40.50.300 3 213 6.4E-37 T 28-03-2018 CIG75_RS00120 205c4b10b3a656c0a4ef93a8c532e378 214 PIRSF PIRSF000705 2 213 1.6E-56 T 28-03-2018 IPR002624 Deoxynucleoside kinase GO:0005524|GO:0006139|GO:0019206 CIG75_RS00120 205c4b10b3a656c0a4ef93a8c532e378 214 Pfam PF01712 Deoxynucleoside kinase 7 205 6.7E-46 T 28-03-2018 IPR031314 Deoxynucleoside kinase domain CIG75_RS17440 416d9e007ed73360bfa874648b06d665 328 Pfam PF01297 Zinc-uptake complex component A periplasmic 49 325 1.3E-47 T 28-03-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 CIG75_RS17440 416d9e007ed73360bfa874648b06d665 328 SUPERFAMILY SSF53807 45 326 6.87E-50 T 28-03-2018 CIG75_RS17440 416d9e007ed73360bfa874648b06d665 328 Gene3D G3DSA:3.40.50.1980 208 327 4.6E-15 T 28-03-2018 CIG75_RS17440 416d9e007ed73360bfa874648b06d665 328 Gene3D G3DSA:3.40.50.1980 37 207 4.6E-37 T 28-03-2018 CIG75_RS12805 8c557a4a1f72a063f45b459b64b61993 520 TIGRFAM TIGR01630 psiM2_ORF9: phage uncharacterized protein, C-terminal domain 358 497 3.5E-28 T 28-03-2018 IPR006517 Archaeophage PsiM2, terminase large subunit CIG75_RS12805 8c557a4a1f72a063f45b459b64b61993 520 Pfam PF03237 Terminase-like family 100 256 2.9E-6 T 28-03-2018 CIG75_RS12805 8c557a4a1f72a063f45b459b64b61993 520 Pfam PF17289 Terminase RNaseH-like domain 356 493 1.5E-5 T 28-03-2018 IPR035421 Terminase, large subunit gp17-like CIG75_RS15485 88538b9c3b3fe957620489227b62890d 207 SUPERFAMILY SSF52833 18 194 2.56E-30 T 28-03-2018 IPR012336 Thioredoxin-like fold CIG75_RS15485 88538b9c3b3fe957620489227b62890d 207 Gene3D G3DSA:3.40.30.10 15 206 6.9E-34 T 28-03-2018 CIG75_RS15485 88538b9c3b3fe957620489227b62890d 207 Pfam PF01323 DSBA-like thioredoxin domain 19 181 7.8E-25 T 28-03-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 CIG75_RS06835 41756dc8efb357edbb88300399b24848 259 Hamap MF_00621 GTP-sensing transcriptional pleiotropic repressor CodY [codY]. 1 259 113.86 T 28-03-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 CIG75_RS06835 41756dc8efb357edbb88300399b24848 259 Pfam PF08222 CodY helix-turn-helix domain 199 257 3.7E-35 T 28-03-2018 IPR013198 GTP-sensing helix-turn-helix, CodY, C-terminal CIG75_RS06835 41756dc8efb357edbb88300399b24848 259 TIGRFAM TIGR02787 codY_Gpos: GTP-sensing transcriptional pleiotropic repressor CodY 3 254 3.9E-100 T 28-03-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 CIG75_RS06835 41756dc8efb357edbb88300399b24848 259 Gene3D G3DSA:3.30.450.40 1 160 1.2E-23 T 28-03-2018 IPR029016 GAF domain-like CIG75_RS06835 41756dc8efb357edbb88300399b24848 259 SUPERFAMILY SSF46785 168 256 2.11E-39 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS06835 41756dc8efb357edbb88300399b24848 259 Pfam PF06018 CodY GAF-like domain 3 179 6.6E-59 T 28-03-2018 IPR010312 GTP-sensing transcriptional pleiotropic repressor CodY, N-terminal GO:0003677|GO:0005525 CIG75_RS06835 41756dc8efb357edbb88300399b24848 259 Gene3D G3DSA:1.10.10.10 161 259 1.9E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS06835 41756dc8efb357edbb88300399b24848 259 PIRSF PIRSF011572 1 258 6.2E-103 T 28-03-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 CIG75_RS14865 c51e6c0c7f9028043995477d769843bc 119 Pfam PF12438 Protein of unknown function (DUF3679) 15 63 4.3E-8 T 28-03-2018 IPR020534 Uncharacterised protein family YqxA CIG75_RS16875 b4cccc6e8e9486c986f7f236ab297578 268 Pfam PF01955 Adenosylcobinamide amidohydrolase 63 256 2.1E-53 T 28-03-2018 IPR002808 Adenosylcobinamide amidohydrolase, CbiZ CIG75_RS16875 b4cccc6e8e9486c986f7f236ab297578 268 Gene3D G3DSA:3.50.50.60 2 256 0.0013 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS00410 bcd637f6f2e799b7ef65edbc97c49026 197 PIRSF PIRSF021308 1 197 3.7E-96 T 28-03-2018 IPR016786 Uncharacterised protein YdeI, bacterial CIG75_RS00410 bcd637f6f2e799b7ef65edbc97c49026 197 Pfam PF08818 Domain of unknown function (DU1801) 20 117 8.4E-14 T 28-03-2018 IPR014922 Domain of unknown function DUF1801 CIG75_RS00410 bcd637f6f2e799b7ef65edbc97c49026 197 Pfam PF13376 Bacteriocin-protection, YdeI or OmpD-Associated 134 191 5.6E-16 T 28-03-2018 CIG75_RS00410 bcd637f6f2e799b7ef65edbc97c49026 197 SUPERFAMILY SSF159888 9 121 7.72E-21 T 28-03-2018 CIG75_RS07235 4ecba33192d75897ddab7f9c4799536d 486 SUPERFAMILY SSF54373 323 431 2.22E-31 T 28-03-2018 CIG75_RS07235 4ecba33192d75897ddab7f9c4799536d 486 Gene3D G3DSA:1.10.3110.10 124 206 2.6E-33 T 28-03-2018 CIG75_RS07235 4ecba33192d75897ddab7f9c4799536d 486 TIGRFAM TIGR00562 proto_IX_ox: protoporphyrinogen oxidase 7 482 1.1E-115 T 28-03-2018 IPR004572 Protoporphyrinogen oxidase GO:0004729|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.4|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CIG75_RS07235 4ecba33192d75897ddab7f9c4799536d 486 SUPERFAMILY SSF51905 7 339 1.78E-58 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS07235 4ecba33192d75897ddab7f9c4799536d 486 SUPERFAMILY SSF51905 449 481 1.78E-58 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS07235 4ecba33192d75897ddab7f9c4799536d 486 Pfam PF01593 Flavin containing amine oxidoreductase 16 481 4.4E-69 T 28-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 CIG75_RS07235 4ecba33192d75897ddab7f9c4799536d 486 Gene3D G3DSA:3.90.660.20 50 123 1.1E-9 T 28-03-2018 CIG75_RS07235 4ecba33192d75897ddab7f9c4799536d 486 Gene3D G3DSA:3.90.660.20 207 431 9.7E-42 T 28-03-2018 CIG75_RS07420 8022ee294b28482da8860b2bf1ee1dc7 140 TIGRFAM TIGR03419 NifU_clost: FeS cluster assembly scaffold protein NifU 2 123 2.5E-63 T 28-03-2018 IPR017787 NIF system FeS cluster assembly, NifU-like CIG75_RS07420 8022ee294b28482da8860b2bf1ee1dc7 140 SUPERFAMILY SSF82649 4 124 7.85E-45 T 28-03-2018 CIG75_RS07420 8022ee294b28482da8860b2bf1ee1dc7 140 Pfam PF01592 NifU-like N terminal domain 1 124 8.4E-52 T 28-03-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 CIG75_RS07420 8022ee294b28482da8860b2bf1ee1dc7 140 Gene3D G3DSA:3.90.1010.10 1 135 2.6E-53 T 28-03-2018 CIG75_RS11180 167efb5633b52f37d2fda3671a01f643 530 Gene3D G3DSA:2.20.110.10 307 471 1.5E-13 T 28-03-2018 CIG75_RS11180 167efb5633b52f37d2fda3671a01f643 530 Gene3D G3DSA:2.20.110.10 244 306 8.9E-14 T 28-03-2018 CIG75_RS11180 167efb5633b52f37d2fda3671a01f643 530 Gene3D G3DSA:2.20.110.10 82 151 2.7E-10 T 28-03-2018 CIG75_RS11180 167efb5633b52f37d2fda3671a01f643 530 Gene3D G3DSA:2.20.110.10 152 240 2.0E-16 T 28-03-2018 CIG75_RS11180 167efb5633b52f37d2fda3671a01f643 530 Pfam PF02493 MORN repeat 99 119 1.9 T 28-03-2018 IPR003409 MORN motif CIG75_RS11180 167efb5633b52f37d2fda3671a01f643 530 Pfam PF02493 MORN repeat 219 238 8.2 T 28-03-2018 IPR003409 MORN motif CIG75_RS11180 167efb5633b52f37d2fda3671a01f643 530 Pfam PF02493 MORN repeat 147 169 0.01 T 28-03-2018 IPR003409 MORN motif CIG75_RS11180 167efb5633b52f37d2fda3671a01f643 530 Pfam PF02493 MORN repeat 315 330 1.2 T 28-03-2018 IPR003409 MORN motif CIG75_RS11180 167efb5633b52f37d2fda3671a01f643 530 Pfam PF02493 MORN repeat 123 136 1.0 T 28-03-2018 IPR003409 MORN motif CIG75_RS11180 167efb5633b52f37d2fda3671a01f643 530 Pfam PF02493 MORN repeat 267 288 0.21 T 28-03-2018 IPR003409 MORN motif CIG75_RS11180 167efb5633b52f37d2fda3671a01f643 530 Pfam PF02493 MORN repeat 339 359 0.71 T 28-03-2018 IPR003409 MORN motif CIG75_RS11180 167efb5633b52f37d2fda3671a01f643 530 Pfam PF02493 MORN repeat 195 216 0.2 T 28-03-2018 IPR003409 MORN motif CIG75_RS11180 167efb5633b52f37d2fda3671a01f643 530 Pfam PF02493 MORN repeat 171 191 0.36 T 28-03-2018 IPR003409 MORN motif CIG75_RS11180 167efb5633b52f37d2fda3671a01f643 530 Pfam PF02493 MORN repeat 291 310 0.0051 T 28-03-2018 IPR003409 MORN motif CIG75_RS11180 167efb5633b52f37d2fda3671a01f643 530 SUPERFAMILY SSF82185 144 266 5.62E-27 T 28-03-2018 CIG75_RS11180 167efb5633b52f37d2fda3671a01f643 530 SMART SM00698 97 118 5.3 T 28-03-2018 IPR003409 MORN motif CIG75_RS11180 167efb5633b52f37d2fda3671a01f643 530 SMART SM00698 169 190 0.68 T 28-03-2018 IPR003409 MORN motif CIG75_RS11180 167efb5633b52f37d2fda3671a01f643 530 SMART SM00698 289 310 0.32 T 28-03-2018 IPR003409 MORN motif CIG75_RS11180 167efb5633b52f37d2fda3671a01f643 530 SMART SM00698 265 286 57.0 T 28-03-2018 IPR003409 MORN motif CIG75_RS11180 167efb5633b52f37d2fda3671a01f643 530 SMART SM00698 313 334 6.9 T 28-03-2018 IPR003409 MORN motif CIG75_RS11180 167efb5633b52f37d2fda3671a01f643 530 SMART SM00698 217 238 56.0 T 28-03-2018 IPR003409 MORN motif CIG75_RS11180 167efb5633b52f37d2fda3671a01f643 530 SMART SM00698 193 214 19.0 T 28-03-2018 IPR003409 MORN motif CIG75_RS11180 167efb5633b52f37d2fda3671a01f643 530 SMART SM00698 337 358 0.95 T 28-03-2018 IPR003409 MORN motif CIG75_RS11180 167efb5633b52f37d2fda3671a01f643 530 SMART SM00698 145 166 4.0 T 28-03-2018 IPR003409 MORN motif CIG75_RS11180 167efb5633b52f37d2fda3671a01f643 530 SUPERFAMILY SSF82185 84 139 6.02E-10 T 28-03-2018 CIG75_RS11180 167efb5633b52f37d2fda3671a01f643 530 SUPERFAMILY SSF82185 263 372 1.31E-23 T 28-03-2018 CIG75_RS11195 def5f97aeadeacd9944a45f29bbf6a6f 701 Gene3D G3DSA:2.120.10.30 196 393 9.0E-9 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CIG75_RS11195 def5f97aeadeacd9944a45f29bbf6a6f 701 SUPERFAMILY SSF63829 52 330 4.18E-15 T 28-03-2018 CIG75_RS11195 def5f97aeadeacd9944a45f29bbf6a6f 701 Gene3D G3DSA:2.120.10.30 22 195 0.0038 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CIG75_RS11195 def5f97aeadeacd9944a45f29bbf6a6f 701 Pfam PF09684 Phage tail protein (Tail_P2_I) 506 632 3.0E-12 T 28-03-2018 IPR006521 Tail protein I CIG75_RS11195 def5f97aeadeacd9944a45f29bbf6a6f 701 TIGRFAM TIGR02242 tail_TIGR02242: phage tail protein domain 468 585 4.2E-31 T 28-03-2018 IPR011748 Uncharacterised protein family, phage tail-like CIG75_RS06440 8fb27d13e640a8ace93b3c2a725274c8 402 Gene3D G3DSA:1.20.1250.20 10 204 4.2E-32 T 28-03-2018 CIG75_RS06440 8fb27d13e640a8ace93b3c2a725274c8 402 Gene3D G3DSA:1.20.1250.20 206 402 1.6E-14 T 28-03-2018 CIG75_RS06440 8fb27d13e640a8ace93b3c2a725274c8 402 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 17 396 1.0E-107 T 28-03-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 CIG75_RS06440 8fb27d13e640a8ace93b3c2a725274c8 402 PRINTS PR01035 Tetracycline resistance protein signature 172 192 2.1E-7 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CIG75_RS06440 8fb27d13e640a8ace93b3c2a725274c8 402 PRINTS PR01035 Tetracycline resistance protein signature 112 133 2.1E-7 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CIG75_RS06440 8fb27d13e640a8ace93b3c2a725274c8 402 PRINTS PR01035 Tetracycline resistance protein signature 85 109 2.1E-7 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CIG75_RS06440 8fb27d13e640a8ace93b3c2a725274c8 402 PRINTS PR01035 Tetracycline resistance protein signature 28 44 2.1E-7 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CIG75_RS06440 8fb27d13e640a8ace93b3c2a725274c8 402 SUPERFAMILY SSF103473 7 399 1.44E-65 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS06440 8fb27d13e640a8ace93b3c2a725274c8 402 Pfam PF07690 Major Facilitator Superfamily 28 366 1.4E-46 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CIG75_RS19545 0a29bc5ec57f61f03a17af764b922548 188 Pfam PF14089 KinB-signalling pathway activation in sporulation 35 180 1.7E-30 T 28-03-2018 IPR024164 KinB-signalling pathway activation protein GO:0045881 CIG75_RS19545 0a29bc5ec57f61f03a17af764b922548 188 SMART SM01251 14 181 2.6E-17 T 28-03-2018 IPR024164 KinB-signalling pathway activation protein GO:0045881 CIG75_RS03535 338f9dc58b7f4c7a90f7fe5fdd4d8709 309 SUPERFAMILY SSF52540 2 222 4.33E-67 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS03535 338f9dc58b7f4c7a90f7fe5fdd4d8709 309 Pfam PF00005 ABC transporter 18 160 5.4E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS03535 338f9dc58b7f4c7a90f7fe5fdd4d8709 309 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS03535 338f9dc58b7f4c7a90f7fe5fdd4d8709 309 SMART SM00382 26 224 4.6E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS03535 338f9dc58b7f4c7a90f7fe5fdd4d8709 309 Gene3D G3DSA:3.40.50.300 1 272 1.4E-68 T 28-03-2018 CIG75_RS03455 7339a34f322d74c524db9241d20fded2 392 PIRSF PIRSF037259 3 391 3.6E-66 T 28-03-2018 IPR010288 Bacterial ABC transporter EcsB GO:0016021 CIG75_RS03455 7339a34f322d74c524db9241d20fded2 392 Pfam PF05975 Bacterial ABC transporter protein EcsB 6 364 8.3E-72 T 28-03-2018 IPR010288 Bacterial ABC transporter EcsB GO:0016021 CIG75_RS12855 80c4de912fb4f5ab897634779ec70e07 163 Pfam PF00196 Bacterial regulatory proteins, luxR family 108 145 4.0E-5 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CIG75_RS12855 80c4de912fb4f5ab897634779ec70e07 163 Gene3D G3DSA:1.10.10.10 63 156 3.5E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS17985 41eb7dd5904b399661e507c61c3d95d7 264 Pfam PF06182 ABC-2 family transporter protein 38 256 4.2E-28 T 28-03-2018 IPR010390 Protein of unknown function DUF990 CIG75_RS02430 4e39f0e09f58517dc83a50bd1fc5f088 294 SUPERFAMILY SSF53328 1 202 3.92E-43 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CIG75_RS02430 4e39f0e09f58517dc83a50bd1fc5f088 294 Gene3D G3DSA:3.10.25.10 203 287 7.0E-22 T 28-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CIG75_RS02430 4e39f0e09f58517dc83a50bd1fc5f088 294 Gene3D G3DSA:3.40.50.170 1 202 1.1E-41 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CIG75_RS02430 4e39f0e09f58517dc83a50bd1fc5f088 294 Pfam PF00551 Formyl transferase 25 168 2.2E-19 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CIG75_RS02430 4e39f0e09f58517dc83a50bd1fc5f088 294 Pfam PF02911 Formyl transferase, C-terminal domain 204 284 1.2E-19 T 28-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CIG75_RS02430 4e39f0e09f58517dc83a50bd1fc5f088 294 SUPERFAMILY SSF50486 203 284 1.88E-20 T 28-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 CIG75_RS16835 587c12694b42bb0ec29e5f7c1e2a6d18 293 Gene3D G3DSA:3.40.50.300 1 262 2.5E-55 T 28-03-2018 CIG75_RS16835 587c12694b42bb0ec29e5f7c1e2a6d18 293 Pfam PF00005 ABC transporter 21 157 1.3E-24 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS16835 587c12694b42bb0ec29e5f7c1e2a6d18 293 SMART SM00382 28 215 2.6E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS16835 587c12694b42bb0ec29e5f7c1e2a6d18 293 SUPERFAMILY SSF52540 2 235 3.48E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS14535 3eb3b6440cdbdf49163a9ff7b7a7a3c0 278 Pfam PF08282 haloacid dehalogenase-like hydrolase 5 247 3.1E-42 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS14535 3eb3b6440cdbdf49163a9ff7b7a7a3c0 278 ProSitePatterns PS01229 Hypothetical cof family signature 2. 211 233 - T 28-03-2018 CIG75_RS14535 3eb3b6440cdbdf49163a9ff7b7a7a3c0 278 Gene3D G3DSA:3.40.50.1000 1 116 2.2E-15 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS14535 3eb3b6440cdbdf49163a9ff7b7a7a3c0 278 Gene3D G3DSA:3.40.50.1000 120 271 6.5E-18 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS14535 3eb3b6440cdbdf49163a9ff7b7a7a3c0 278 SUPERFAMILY SSF56784 1 246 2.53E-47 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS14535 3eb3b6440cdbdf49163a9ff7b7a7a3c0 278 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 4 230 2.0E-21 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CIG75_RS01835 a3f6e4a55db046b6019239b18483932a 140 Pfam PF02254 TrkA-N domain 41 118 4.2E-6 T 28-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 CIG75_RS01835 a3f6e4a55db046b6019239b18483932a 140 SUPERFAMILY SSF51735 5 118 1.75E-9 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS01835 a3f6e4a55db046b6019239b18483932a 140 Gene3D G3DSA:3.40.50.720 9 131 2.6E-8 T 28-03-2018 CIG75_RS02435 d3a2a3b234ac95726b645fb8934078f9 222 Pfam PF02585 GlcNAc-PI de-N-acetylase 5 125 8.8E-18 T 28-03-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 CIG75_RS02435 d3a2a3b234ac95726b645fb8934078f9 222 Gene3D G3DSA:3.40.50.10320 1 222 3.6E-41 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CIG75_RS02435 d3a2a3b234ac95726b645fb8934078f9 222 SUPERFAMILY SSF102588 2 219 1.03E-45 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CIG75_RS16545 f10025e550b1060ce7fe62dadd1f2bd9 1102 Pfam PF12705 PD-(D/E)XK nuclease superfamily 783 1080 1.1E-40 T 28-03-2018 CIG75_RS16545 f10025e550b1060ce7fe62dadd1f2bd9 1102 Gene3D G3DSA:3.40.50.300 272 714 4.3E-21 T 28-03-2018 CIG75_RS16545 f10025e550b1060ce7fe62dadd1f2bd9 1102 Gene3D G3DSA:3.90.320.10 715 997 3.5E-19 T 28-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 CIG75_RS16545 f10025e550b1060ce7fe62dadd1f2bd9 1102 Gene3D G3DSA:3.40.50.300 14 271 0.0011 T 28-03-2018 CIG75_RS16545 f10025e550b1060ce7fe62dadd1f2bd9 1102 SUPERFAMILY SSF52980 781 990 5.9E-6 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CIG75_RS16545 f10025e550b1060ce7fe62dadd1f2bd9 1102 SUPERFAMILY SSF52540 308 688 3.51E-25 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS02550 62f1f5ab0b476fc2f87d992f78b12485 266 SMART SM00382 27 211 9.6E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS02550 62f1f5ab0b476fc2f87d992f78b12485 266 SUPERFAMILY SSF52540 3 224 2.27E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS02550 62f1f5ab0b476fc2f87d992f78b12485 266 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS02550 62f1f5ab0b476fc2f87d992f78b12485 266 Gene3D G3DSA:3.40.50.300 1 242 2.9E-61 T 28-03-2018 CIG75_RS02550 62f1f5ab0b476fc2f87d992f78b12485 266 Pfam PF00005 ABC transporter 19 167 1.5E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS04390 0461d94a78179d58027d13d756d5ae80 380 SMART SM00388 167 235 9.9E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CIG75_RS04390 0461d94a78179d58027d13d756d5ae80 380 SMART SM00387 276 380 2.4E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS04390 0461d94a78179d58027d13d756d5ae80 380 SUPERFAMILY SSF47384 163 232 9.42E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CIG75_RS04390 0461d94a78179d58027d13d756d5ae80 380 SUPERFAMILY SSF55785 40 150 1.41E-8 T 28-03-2018 IPR000014 PAS domain CIG75_RS04390 0461d94a78179d58027d13d756d5ae80 380 Gene3D G3DSA:1.10.287.130 161 231 2.3E-16 T 28-03-2018 CIG75_RS04390 0461d94a78179d58027d13d756d5ae80 380 Pfam PF08448 PAS fold 52 153 3.3E-8 T 28-03-2018 IPR013656 PAS fold-4 CIG75_RS04390 0461d94a78179d58027d13d756d5ae80 380 Gene3D G3DSA:3.30.565.10 236 380 4.1E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS04390 0461d94a78179d58027d13d756d5ae80 380 SMART SM00091 45 111 0.0023 T 28-03-2018 IPR000014 PAS domain CIG75_RS04390 0461d94a78179d58027d13d756d5ae80 380 SUPERFAMILY SSF55874 234 379 6.42E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS04390 0461d94a78179d58027d13d756d5ae80 380 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 279 379 2.8E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS04390 0461d94a78179d58027d13d756d5ae80 380 Gene3D G3DSA:3.30.450.20 31 160 2.1E-13 T 28-03-2018 CIG75_RS04390 0461d94a78179d58027d13d756d5ae80 380 Pfam PF00512 His Kinase A (phospho-acceptor) domain 169 231 9.1E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CIG75_RS04390 0461d94a78179d58027d13d756d5ae80 380 PRINTS PR00344 Bacterial sensor protein C-terminal signature 313 327 5.1E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS04390 0461d94a78179d58027d13d756d5ae80 380 PRINTS PR00344 Bacterial sensor protein C-terminal signature 366 379 5.1E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS04390 0461d94a78179d58027d13d756d5ae80 380 PRINTS PR00344 Bacterial sensor protein C-terminal signature 331 341 5.1E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS04390 0461d94a78179d58027d13d756d5ae80 380 PRINTS PR00344 Bacterial sensor protein C-terminal signature 342 360 5.1E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS11940 e7e2f30c48e0a83e991955250c560a92 158 Gene3D G3DSA:2.40.50.180 128 156 0.05 T 28-03-2018 CIG75_RS11940 e7e2f30c48e0a83e991955250c560a92 158 Gene3D G3DSA:2.40.50.180 26 93 9.7E-23 T 28-03-2018 CIG75_RS11940 e7e2f30c48e0a83e991955250c560a92 158 SMART SM00260 8 145 3.5E-46 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CIG75_RS11940 e7e2f30c48e0a83e991955250c560a92 158 Gene3D G3DSA:2.30.30.40 94 127 3.1E-19 T 28-03-2018 CIG75_RS11940 e7e2f30c48e0a83e991955250c560a92 158 Pfam PF01584 CheW-like domain 13 148 1.6E-37 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CIG75_RS11940 e7e2f30c48e0a83e991955250c560a92 158 SUPERFAMILY SSF50341 9 149 9.02E-39 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CIG75_RS05750 b777d488d1b9e93d5264192b1258b2e2 294 Gene3D G3DSA:1.10.530.10 1 149 4.2E-6 T 28-03-2018 CIG75_RS05750 b777d488d1b9e93d5264192b1258b2e2 294 Pfam PF01551 Peptidase family M23 171 268 6.1E-22 T 28-03-2018 IPR016047 Peptidase M23 CIG75_RS05750 b777d488d1b9e93d5264192b1258b2e2 294 SUPERFAMILY SSF51261 121 282 1.67E-35 T 28-03-2018 IPR011055 Duplicated hybrid motif CIG75_RS05750 b777d488d1b9e93d5264192b1258b2e2 294 Gene3D G3DSA:2.70.70.10 150 294 1.2E-30 T 28-03-2018 CIG75_RS13655 89890ac5fc092b846e9b07f2a9b0952d 169 ProSitePatterns PS00855 Signal peptidases II signature. 98 110 - T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CIG75_RS13655 89890ac5fc092b846e9b07f2a9b0952d 169 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 128 144 5.8E-12 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CIG75_RS13655 89890ac5fc092b846e9b07f2a9b0952d 169 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 95 110 5.8E-12 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CIG75_RS13655 89890ac5fc092b846e9b07f2a9b0952d 169 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 50 58 5.8E-12 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CIG75_RS13655 89890ac5fc092b846e9b07f2a9b0952d 169 Pfam PF01252 Signal peptidase (SPase) II 13 144 1.2E-27 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CIG75_RS13655 89890ac5fc092b846e9b07f2a9b0952d 169 TIGRFAM TIGR00077 lspA: signal peptidase II 2 154 1.1E-25 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CIG75_RS13655 89890ac5fc092b846e9b07f2a9b0952d 169 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 3 153 13.742 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CIG75_RS01240 a9bcc8f5e553d195bc9e0ad77b0bbe0d 236 Gene3D G3DSA:1.10.101.10 23 107 5.7E-21 T 28-03-2018 IPR002477 Peptidoglycan binding-like CIG75_RS01240 a9bcc8f5e553d195bc9e0ad77b0bbe0d 236 Pfam PF01471 Putative peptidoglycan binding domain 38 98 1.3E-14 T 28-03-2018 IPR002477 Peptidoglycan binding-like CIG75_RS01240 a9bcc8f5e553d195bc9e0ad77b0bbe0d 236 SUPERFAMILY SSF47090 26 100 2.67E-18 T 28-03-2018 IPR002477 Peptidoglycan binding-like CIG75_RS01240 a9bcc8f5e553d195bc9e0ad77b0bbe0d 236 SUPERFAMILY SSF55166 110 221 3.65E-26 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CIG75_RS01240 a9bcc8f5e553d195bc9e0ad77b0bbe0d 236 Gene3D G3DSA:3.30.1380.10 110 230 6.9E-23 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CIG75_RS01240 a9bcc8f5e553d195bc9e0ad77b0bbe0d 236 Pfam PF08291 Peptidase M15 110 220 7.2E-21 T 28-03-2018 IPR013230 Peptidase M15A, C-terminal KEGG: 00550+3.4.17.14|MetaCyc: PWY-6470 CIG75_RS02975 6f67a7f8ad43f1a216411d35f564bb9f 458 Pfam PF00672 HAMP domain 184 233 4.7E-12 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CIG75_RS02975 6f67a7f8ad43f1a216411d35f564bb9f 458 SUPERFAMILY SSF55874 293 456 6.94E-43 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS02975 6f67a7f8ad43f1a216411d35f564bb9f 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 402 412 9.1E-18 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS02975 6f67a7f8ad43f1a216411d35f564bb9f 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 419 437 9.1E-18 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS02975 6f67a7f8ad43f1a216411d35f564bb9f 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 443 456 9.1E-18 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS02975 6f67a7f8ad43f1a216411d35f564bb9f 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 384 398 9.1E-18 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CIG75_RS02975 6f67a7f8ad43f1a216411d35f564bb9f 458 SUPERFAMILY SSF47384 220 302 4.71E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CIG75_RS02975 6f67a7f8ad43f1a216411d35f564bb9f 458 Gene3D G3DSA:3.30.565.10 307 458 2.4E-42 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS02975 6f67a7f8ad43f1a216411d35f564bb9f 458 SMART SM00388 237 303 4.8E-19 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CIG75_RS02975 6f67a7f8ad43f1a216411d35f564bb9f 458 Pfam PF00512 His Kinase A (phospho-acceptor) domain 237 302 3.5E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CIG75_RS02975 6f67a7f8ad43f1a216411d35f564bb9f 458 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 350 457 4.7E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS02975 6f67a7f8ad43f1a216411d35f564bb9f 458 Gene3D G3DSA:1.10.287.130 227 298 9.1E-18 T 28-03-2018 CIG75_RS02975 6f67a7f8ad43f1a216411d35f564bb9f 458 SMART SM00387 347 458 4.4E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CIG75_RS02975 6f67a7f8ad43f1a216411d35f564bb9f 458 SUPERFAMILY SSF158472 184 234 1.44E-12 T 28-03-2018 CIG75_RS02975 6f67a7f8ad43f1a216411d35f564bb9f 458 SMART SM00304 184 236 2.9E-14 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CIG75_RS12115 2af6b44ad303e3bac173112c4d3a2bc2 370 Gene3D G3DSA:3.40.50.450 111 260 1.2E-38 T 28-03-2018 CIG75_RS12115 2af6b44ad303e3bac173112c4d3a2bc2 370 Pfam PF02481 DNA recombination-mediator protein A 71 277 7.3E-78 T 28-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 CIG75_RS12115 2af6b44ad303e3bac173112c4d3a2bc2 370 Gene3D G3DSA:1.10.10.10 292 366 9.3E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS12115 2af6b44ad303e3bac173112c4d3a2bc2 370 Gene3D G3DSA:1.10.150.20 6 57 8.3E-5 T 28-03-2018 CIG75_RS12115 2af6b44ad303e3bac173112c4d3a2bc2 370 SUPERFAMILY SSF102405 82 283 7.1E-36 T 28-03-2018 CIG75_RS12115 2af6b44ad303e3bac173112c4d3a2bc2 370 SUPERFAMILY SSF47781 14 76 1.02E-6 T 28-03-2018 IPR010994 RuvA domain 2-like CIG75_RS12115 2af6b44ad303e3bac173112c4d3a2bc2 370 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 71 286 4.0E-76 T 28-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 CIG75_RS16655 8551257143f67244d05e2d0866a37861 287 Pfam PF00248 Aldo/keto reductase family 16 214 5.9E-28 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CIG75_RS16655 8551257143f67244d05e2d0866a37861 287 SUPERFAMILY SSF51430 1 258 1.01E-50 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CIG75_RS16655 8551257143f67244d05e2d0866a37861 287 Gene3D G3DSA:3.20.20.100 213 264 0.0049 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CIG75_RS16655 8551257143f67244d05e2d0866a37861 287 Gene3D G3DSA:3.20.20.100 1 212 2.0E-37 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CIG75_RS01120 93c22d0408bd2f2557118bc26a3652bf 99 TIGRFAM TIGR03954 integ_memb_HG: integral membrane protein 11 93 2.3E-29 T 28-03-2018 IPR023845 Domain of unknown function DUF3817, transmembrane CIG75_RS01120 93c22d0408bd2f2557118bc26a3652bf 99 Pfam PF12823 Domain of unknown function (DUF3817) 8 94 4.9E-24 T 28-03-2018 IPR023845 Domain of unknown function DUF3817, transmembrane CIG75_RS12660 108bc9dfd75b69f3e17666980c0adadc 259 PIRSF PIRSF003073 1 253 6.7E-85 T 28-03-2018 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein CIG75_RS12660 108bc9dfd75b69f3e17666980c0adadc 259 SMART SM00382 99 232 2.3E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS12660 108bc9dfd75b69f3e17666980c0adadc 259 SUPERFAMILY SSF52540 65 239 1.04E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS12660 108bc9dfd75b69f3e17666980c0adadc 259 Gene3D G3DSA:3.40.50.300 45 232 1.6E-18 T 28-03-2018 CIG75_RS12660 108bc9dfd75b69f3e17666980c0adadc 259 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 190 204 8.2E-5 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CIG75_RS12660 108bc9dfd75b69f3e17666980c0adadc 259 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 103 121 8.2E-5 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CIG75_RS12660 108bc9dfd75b69f3e17666980c0adadc 259 Pfam PF01695 IstB-like ATP binding protein 55 230 1.9E-68 T 28-03-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 CIG75_RS10560 10869d794bc20d1029ec3e05e80a06d5 287 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 51 182 5.3E-19 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CIG75_RS10560 10869d794bc20d1029ec3e05e80a06d5 287 SUPERFAMILY SSF52540 11 267 1.24E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS10560 10869d794bc20d1029ec3e05e80a06d5 287 Gene3D G3DSA:3.40.50.300 1 182 2.8E-23 T 28-03-2018 CIG75_RS10560 10869d794bc20d1029ec3e05e80a06d5 287 PRINTS PR00819 CbxX/CfqX superfamily signature 10 24 6.0E-58 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CIG75_RS10560 10869d794bc20d1029ec3e05e80a06d5 287 PRINTS PR00819 CbxX/CfqX superfamily signature 102 121 6.0E-58 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CIG75_RS10560 10869d794bc20d1029ec3e05e80a06d5 287 PRINTS PR00819 CbxX/CfqX superfamily signature 88 102 6.0E-58 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CIG75_RS10560 10869d794bc20d1029ec3e05e80a06d5 287 PRINTS PR00819 CbxX/CfqX superfamily signature 170 189 6.0E-58 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CIG75_RS10560 10869d794bc20d1029ec3e05e80a06d5 287 PRINTS PR00819 CbxX/CfqX superfamily signature 132 144 6.0E-58 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CIG75_RS10560 10869d794bc20d1029ec3e05e80a06d5 287 PRINTS PR00819 CbxX/CfqX superfamily signature 229 241 6.0E-58 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CIG75_RS10560 10869d794bc20d1029ec3e05e80a06d5 287 PRINTS PR00819 CbxX/CfqX superfamily signature 50 65 6.0E-58 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CIG75_RS10560 10869d794bc20d1029ec3e05e80a06d5 287 PRINTS PR00819 CbxX/CfqX superfamily signature 153 170 6.0E-58 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CIG75_RS10560 10869d794bc20d1029ec3e05e80a06d5 287 SMART SM00382 47 185 1.6E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS10560 10869d794bc20d1029ec3e05e80a06d5 287 TIGRFAM TIGR02881 spore_V_K: stage V sporulation protein K 8 267 3.3E-129 T 28-03-2018 IPR014232 Sporulation stage V, protein K CIG75_RS07230 bd47d7797b596ee2aa552d34a7521092 311 Hamap MF_00323 Ferrochelatase [hemH]. 4 308 30.909 T 28-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CIG75_RS07230 bd47d7797b596ee2aa552d34a7521092 311 ProSitePatterns PS00534 Ferrochelatase signature. 179 197 - T 28-03-2018 IPR019772 Ferrochelatase, active site GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CIG75_RS07230 bd47d7797b596ee2aa552d34a7521092 311 Pfam PF00762 Ferrochelatase 6 307 4.8E-86 T 28-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CIG75_RS07230 bd47d7797b596ee2aa552d34a7521092 311 TIGRFAM TIGR00109 hemH: ferrochelatase 2 307 3.5E-74 T 28-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CIG75_RS07230 bd47d7797b596ee2aa552d34a7521092 311 Gene3D G3DSA:3.40.50.1400 159 289 8.3E-45 T 28-03-2018 CIG75_RS07230 bd47d7797b596ee2aa552d34a7521092 311 Gene3D G3DSA:3.40.50.1400 1 158 3.6E-28 T 28-03-2018 CIG75_RS07230 bd47d7797b596ee2aa552d34a7521092 311 SUPERFAMILY SSF53800 3 308 4.74E-89 T 28-03-2018 CIG75_RS17480 da7e171cf5f67b13a2b0468e90dc7573 160 Gene3D G3DSA:2.60.120.260 39 160 3.0E-8 T 28-03-2018 IPR008979 Galactose-binding domain-like CIG75_RS08410 48739494b2c7c11a9d032d9b895c69b7 481 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 362 470 1.7E-35 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CIG75_RS08410 48739494b2c7c11a9d032d9b895c69b7 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 144 162 2.0E-37 T 28-03-2018 CIG75_RS08410 48739494b2c7c11a9d032d9b895c69b7 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 307 329 2.0E-37 T 28-03-2018 CIG75_RS08410 48739494b2c7c11a9d032d9b895c69b7 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 2.0E-37 T 28-03-2018 CIG75_RS08410 48739494b2c7c11a9d032d9b895c69b7 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 183 201 2.0E-37 T 28-03-2018 CIG75_RS08410 48739494b2c7c11a9d032d9b895c69b7 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 279 295 2.0E-37 T 28-03-2018 CIG75_RS08410 48739494b2c7c11a9d032d9b895c69b7 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 322 329 1.6E-68 T 28-03-2018 CIG75_RS08410 48739494b2c7c11a9d032d9b895c69b7 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 1.6E-68 T 28-03-2018 CIG75_RS08410 48739494b2c7c11a9d032d9b895c69b7 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 280 294 1.6E-68 T 28-03-2018 CIG75_RS08410 48739494b2c7c11a9d032d9b895c69b7 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 1.6E-68 T 28-03-2018 CIG75_RS08410 48739494b2c7c11a9d032d9b895c69b7 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 183 208 1.6E-68 T 28-03-2018 CIG75_RS08410 48739494b2c7c11a9d032d9b895c69b7 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 147 156 1.6E-68 T 28-03-2018 CIG75_RS08410 48739494b2c7c11a9d032d9b895c69b7 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 358 379 1.6E-68 T 28-03-2018 CIG75_RS08410 48739494b2c7c11a9d032d9b895c69b7 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 423 438 1.6E-68 T 28-03-2018 CIG75_RS08410 48739494b2c7c11a9d032d9b895c69b7 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 445 465 1.6E-68 T 28-03-2018 CIG75_RS08410 48739494b2c7c11a9d032d9b895c69b7 481 SUPERFAMILY SSF55424 358 480 2.06E-39 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CIG75_RS08410 48739494b2c7c11a9d032d9b895c69b7 481 PIRSF PIRSF000350 1 479 1.5E-81 T 28-03-2018 CIG75_RS08410 48739494b2c7c11a9d032d9b895c69b7 481 Gene3D G3DSA:3.30.390.30 350 478 1.5E-40 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CIG75_RS08410 48739494b2c7c11a9d032d9b895c69b7 481 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 342 3.3E-60 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS08410 48739494b2c7c11a9d032d9b895c69b7 481 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 39 49 - T 28-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 CIG75_RS08410 48739494b2c7c11a9d032d9b895c69b7 481 Gene3D G3DSA:3.50.50.60 1 173 1.1E-28 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS08410 48739494b2c7c11a9d032d9b895c69b7 481 Gene3D G3DSA:3.40.50.720 174 349 1.0E-32 T 28-03-2018 CIG75_RS08410 48739494b2c7c11a9d032d9b895c69b7 481 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 4 481 1.9E-170 T 28-03-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 CIG75_RS08410 48739494b2c7c11a9d032d9b895c69b7 481 SUPERFAMILY SSF51905 1 352 2.59E-58 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS02340 766475d60d517a221b8cb5867b4dd42a 88 SUPERFAMILY SSF101498 1 85 5.36E-13 T 28-03-2018 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 CIG75_RS02340 766475d60d517a221b8cb5867b4dd42a 88 Gene3D G3DSA:1.10.287.1160 55 84 1.2E-9 T 28-03-2018 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 CIG75_RS02340 766475d60d517a221b8cb5867b4dd42a 88 TIGRFAM TIGR03824 FlgM_jcvi: flagellar biosynthesis anti-sigma factor FlgM 1 84 5.6E-12 T 28-03-2018 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 CIG75_RS02340 766475d60d517a221b8cb5867b4dd42a 88 Pfam PF04316 Anti-sigma-28 factor, FlgM 35 83 2.0E-11 T 28-03-2018 IPR031316 Anti-sigma-28 factor FlgM, C-terminal CIG75_RS17225 2a6b12d0699b1c8b9c3908baa5ad1f15 446 PIRSF PIRSF005690 7 444 1.5E-110 T 28-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 CIG75_RS17225 2a6b12d0699b1c8b9c3908baa5ad1f15 446 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 16 438 1.7E-106 T 28-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 CIG75_RS10215 fead181a014cb23e207bef2ee7dcfa54 384 PIRSF PIRSF016719 1 384 1.3E-141 T 28-03-2018 IPR008302 Uncharacterised conserved protein UCP016719 CIG75_RS10215 fead181a014cb23e207bef2ee7dcfa54 384 Pfam PF07075 Protein of unknown function (DUF1343) 22 383 5.1E-134 T 28-03-2018 IPR008302 Uncharacterised conserved protein UCP016719 CIG75_RS12905 872b6eaa13b236d2adf129534c086797 313 SUPERFAMILY SSF52540 133 277 1.35E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS12905 872b6eaa13b236d2adf129534c086797 313 SMART SM00382 154 280 0.0088 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS12905 872b6eaa13b236d2adf129534c086797 313 Gene3D G3DSA:3.40.50.300 101 298 4.4E-14 T 28-03-2018 CIG75_RS12905 872b6eaa13b236d2adf129534c086797 313 Pfam PF01695 IstB-like ATP binding protein 155 259 2.1E-14 T 28-03-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 CIG75_RS14895 061eddfc75ec16b3afa4f75206ec5988 344 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 21 339 6.8E-80 T 28-03-2018 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 CIG75_RS14895 061eddfc75ec16b3afa4f75206ec5988 344 Gene3D G3DSA:1.10.8.60 150 228 1.2E-17 T 28-03-2018 CIG75_RS14895 061eddfc75ec16b3afa4f75206ec5988 344 Gene3D G3DSA:1.20.272.10 229 343 1.5E-31 T 28-03-2018 CIG75_RS14895 061eddfc75ec16b3afa4f75206ec5988 344 SUPERFAMILY SSF48019 220 339 4.08E-24 T 28-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CIG75_RS14895 061eddfc75ec16b3afa4f75206ec5988 344 SUPERFAMILY SSF52540 13 213 3.51E-25 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS14895 061eddfc75ec16b3afa4f75206ec5988 344 Gene3D G3DSA:3.40.50.300 1 147 8.4E-25 T 28-03-2018 CIG75_RS14895 061eddfc75ec16b3afa4f75206ec5988 344 Pfam PF06144 DNA polymerase III, delta subunit 22 197 1.5E-44 T 28-03-2018 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 CIG75_RS03070 ce789227747f3018cfaee90655cd52e6 500 SUPERFAMILY SSF103473 10 199 1.1E-72 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS03070 ce789227747f3018cfaee90655cd52e6 500 SUPERFAMILY SSF103473 465 491 1.1E-72 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS03070 ce789227747f3018cfaee90655cd52e6 500 SUPERFAMILY SSF103473 246 416 1.1E-72 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS03070 ce789227747f3018cfaee90655cd52e6 500 Gene3D G3DSA:1.20.1250.20 249 499 7.9E-30 T 28-03-2018 CIG75_RS03070 ce789227747f3018cfaee90655cd52e6 500 Pfam PF07690 Major Facilitator Superfamily 15 406 4.0E-54 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CIG75_RS03070 ce789227747f3018cfaee90655cd52e6 500 PRINTS PR01036 Tetracycline resistance protein TetB signature 299 323 7.9E-6 T 28-03-2018 CIG75_RS03070 ce789227747f3018cfaee90655cd52e6 500 PRINTS PR01036 Tetracycline resistance protein TetB signature 73 95 7.9E-6 T 28-03-2018 CIG75_RS03070 ce789227747f3018cfaee90655cd52e6 500 PRINTS PR01036 Tetracycline resistance protein TetB signature 134 158 7.9E-6 T 28-03-2018 CIG75_RS03070 ce789227747f3018cfaee90655cd52e6 500 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 12 485 5.8E-86 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CIG75_RS03070 ce789227747f3018cfaee90655cd52e6 500 Gene3D G3DSA:1.20.1250.20 10 198 1.5E-39 T 28-03-2018 CIG75_RS00380 b2816cb2763ae4a629fbc79dedf963fa 303 Pfam PF05791 Bacillus haemolytic enterotoxin (HBL) 44 178 6.9E-10 T 28-03-2018 IPR008414 Hemolysin BL-binding component GO:0009405|GO:0016020 CIG75_RS00380 b2816cb2763ae4a629fbc79dedf963fa 303 Gene3D G3DSA:1.20.1170.10 13 298 5.6E-20 T 28-03-2018 CIG75_RS00380 b2816cb2763ae4a629fbc79dedf963fa 303 SUPERFAMILY SSF58100 30 298 5.75E-23 T 28-03-2018 CIG75_RS13610 907ff0fdcba0e3d95bddec1efd081299 172 Gene3D G3DSA:3.40.30.10 3 172 1.5E-24 T 28-03-2018 CIG75_RS13610 907ff0fdcba0e3d95bddec1efd081299 172 Hamap MF_00269 Probable thiol peroxidase [tpx]. 9 169 37.19 T 28-03-2018 IPR002065 Putative thiol peroxidase Tpx GO:0008379|GO:0016209|GO:0055114 CIG75_RS13610 907ff0fdcba0e3d95bddec1efd081299 172 Pfam PF08534 Redoxin 25 165 4.1E-20 T 28-03-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 CIG75_RS13610 907ff0fdcba0e3d95bddec1efd081299 172 SUPERFAMILY SSF52833 10 166 4.48E-41 T 28-03-2018 IPR012336 Thioredoxin-like fold CIG75_RS13610 907ff0fdcba0e3d95bddec1efd081299 172 ProSitePatterns PS01265 Tpx family signature. 89 100 - T 28-03-2018 IPR018219 Thiol peroxidase conserved site GO:0016684|GO:0055114 CIG75_RS05000 a9feb00f722fdf39ed2235baef4be92e 294 PIRSF PIRSF006483 5 293 6.5E-98 T 28-03-2018 IPR003740 Uncharacterised membrane protein YitT CIG75_RS05000 a9feb00f722fdf39ed2235baef4be92e 294 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 231 285 1.7E-20 T 28-03-2018 IPR019264 Domain of unknown function DUF2179 CIG75_RS05000 a9feb00f722fdf39ed2235baef4be92e 294 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 23 225 1.4E-66 T 28-03-2018 IPR003740 Uncharacterised membrane protein YitT CIG75_RS18735 bc74a6ed44a933fd0730fc2b783c4e8e 375 SUPERFAMILY SSF51261 159 374 4.03E-51 T 28-03-2018 IPR011055 Duplicated hybrid motif CIG75_RS18735 bc74a6ed44a933fd0730fc2b783c4e8e 375 Gene3D G3DSA:2.70.70.10 166 375 8.3E-49 T 28-03-2018 CIG75_RS18735 bc74a6ed44a933fd0730fc2b783c4e8e 375 Gene3D G3DSA:1.20.5.50 57 136 0.0042 T 28-03-2018 CIG75_RS18735 bc74a6ed44a933fd0730fc2b783c4e8e 375 Pfam PF01551 Peptidase family M23 274 370 9.7E-28 T 28-03-2018 IPR016047 Peptidase M23 CIG75_RS09350 3b2bb94a2b457e660613c305d05a47a4 196 TIGRFAM TIGR00530 AGP_acyltrn: 1-acylglycerol-3-phosphate O-acyltransferases 23 144 1.5E-30 T 28-03-2018 IPR004552 1-acyl-sn-glycerol-3-phosphate acyltransferase GO:0003841|GO:0008654|GO:0016020 KEGG: 00561+2.3.1.51|KEGG: 00564+2.3.1.51|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7417|MetaCyc: PWY-7587|MetaCyc: PWY-7589|MetaCyc: PWY-7782|Reactome: R-HSA-1483166 CIG75_RS09350 3b2bb94a2b457e660613c305d05a47a4 196 SMART SM00563 35 147 1.9E-36 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CIG75_RS09350 3b2bb94a2b457e660613c305d05a47a4 196 Pfam PF01553 Acyltransferase 22 144 6.0E-25 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CIG75_RS09350 3b2bb94a2b457e660613c305d05a47a4 196 SUPERFAMILY SSF69593 3 194 4.32E-53 T 28-03-2018 CIG75_RS09350 3b2bb94a2b457e660613c305d05a47a4 196 Gene3D G3DSA:3.40.1130.10 1 196 1.5E-46 T 28-03-2018 CIG75_RS05150 ea1684cad17db352642e61a5080f0efa 510 SUPERFAMILY SSF48239 128 310 4.97E-23 T 28-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CIG75_RS05150 ea1684cad17db352642e61a5080f0efa 510 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 171 191 6.3E-4 T 28-03-2018 IPR001330 PFTB repeat GO:0003824 CIG75_RS05150 ea1684cad17db352642e61a5080f0efa 510 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 221 241 5.9 T 28-03-2018 IPR001330 PFTB repeat GO:0003824 CIG75_RS05150 ea1684cad17db352642e61a5080f0efa 510 Pfam PF00395 S-layer homology domain 337 379 5.4E-6 T 28-03-2018 IPR001119 S-layer homology domain CIG75_RS05150 ea1684cad17db352642e61a5080f0efa 510 Pfam PF00395 S-layer homology domain 398 440 4.3E-6 T 28-03-2018 IPR001119 S-layer homology domain CIG75_RS05150 ea1684cad17db352642e61a5080f0efa 510 Gene3D G3DSA:1.50.10.20 160 324 2.7E-24 T 28-03-2018 CIG75_RS05150 ea1684cad17db352642e61a5080f0efa 510 Gene3D G3DSA:1.50.10.20 3 159 0.18 T 28-03-2018 CIG75_RS08560 973e43eb69bff791348362137c50e92b 372 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 137 2.3E-46 T 28-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal CIG75_RS08560 973e43eb69bff791348362137c50e92b 372 Gene3D G3DSA:3.40.50.720 188 372 9.6E-46 T 28-03-2018 CIG75_RS08560 973e43eb69bff791348362137c50e92b 372 Gene3D G3DSA:3.40.50.720 1 187 2.5E-41 T 28-03-2018 CIG75_RS08560 973e43eb69bff791348362137c50e92b 372 PIRSF PIRSF000183 1 372 1.2E-182 T 28-03-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 CIG75_RS08560 973e43eb69bff791348362137c50e92b 372 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 173 198 - T 28-03-2018 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 Reactome: R-HSA-71403 CIG75_RS08560 973e43eb69bff791348362137c50e92b 372 SMART SM01003 4 137 1.2E-77 T 28-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal CIG75_RS08560 973e43eb69bff791348362137c50e92b 372 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 1 371 3.5E-177 T 28-03-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 CIG75_RS08560 973e43eb69bff791348362137c50e92b 372 SUPERFAMILY SSF52283 1 137 1.11E-65 T 28-03-2018 CIG75_RS08560 973e43eb69bff791348362137c50e92b 372 SUPERFAMILY SSF52283 306 361 1.11E-65 T 28-03-2018 CIG75_RS08560 973e43eb69bff791348362137c50e92b 372 SUPERFAMILY SSF51735 137 304 3.36E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS08560 973e43eb69bff791348362137c50e92b 372 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 141 353 6.6E-84 T 28-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CIG75_RS08560 973e43eb69bff791348362137c50e92b 372 SMART SM01002 149 298 9.2E-85 T 28-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CIG75_RS02565 d648738db52ae34c9bbef0d1fcfa123a 45 Gene3D G3DSA:3.40.1350.10 1 45 1.6E-5 T 28-03-2018 CIG75_RS02565 d648738db52ae34c9bbef0d1fcfa123a 45 Pfam PF08722 TnsA endonuclease N terminal 5 41 4.3E-6 T 28-03-2018 IPR014833 TnsA endonuclease, N-terminal CIG75_RS14225 13753ff8a574d8fef5abb71bcfdb0d99 179 Gene3D G3DSA:1.20.1260.10 1 158 5.7E-18 T 28-03-2018 IPR012347 Ferritin-related CIG75_RS14225 13753ff8a574d8fef5abb71bcfdb0d99 179 Pfam PF07875 Coat F domain 100 162 2.9E-14 T 28-03-2018 IPR012851 Spore coat protein CotF-like CIG75_RS07785 7c500496d0e8fd026755816a06984b51 104 Pfam PF02627 Carboxymuconolactone decarboxylase family 11 91 4.2E-15 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CIG75_RS07785 7c500496d0e8fd026755816a06984b51 104 Gene3D G3DSA:1.20.1290.10 2 104 1.9E-19 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CIG75_RS07785 7c500496d0e8fd026755816a06984b51 104 SUPERFAMILY SSF69118 5 99 2.62E-24 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CIG75_RS05390 b998ef424e7f2ce42595d3ee710ab369 632 SUPERFAMILY SSF52540 406 462 5.53E-12 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS05390 b998ef424e7f2ce42595d3ee710ab369 632 SUPERFAMILY SSF52540 69 167 5.53E-12 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS05390 b998ef424e7f2ce42595d3ee710ab369 632 SUPERFAMILY SSF52540 242 364 5.53E-12 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS05390 b998ef424e7f2ce42595d3ee710ab369 632 PIRSF PIRSF000549 1 632 9.3E-264 T 28-03-2018 IPR016230 Serine-protein kinase, PrkA GO:0004672 CIG75_RS05390 b998ef424e7f2ce42595d3ee710ab369 632 Gene3D G3DSA:3.40.50.300 94 613 1.5E-6 T 28-03-2018 CIG75_RS05390 b998ef424e7f2ce42595d3ee710ab369 632 SMART SM00763 21 372 5.8E-192 T 28-03-2018 IPR013153 PrkA AAA domain CIG75_RS05390 b998ef424e7f2ce42595d3ee710ab369 632 Pfam PF08298 PrkA AAA domain 22 370 9.4E-144 T 28-03-2018 IPR013153 PrkA AAA domain CIG75_RS05390 b998ef424e7f2ce42595d3ee710ab369 632 Pfam PF06798 PrkA serine protein kinase C-terminal domain 376 625 1.3E-97 T 28-03-2018 IPR010650 PrkA C-terminal domain CIG75_RS03685 46b38ba663c040b7e7648b738c8af4fd 400 SUPERFAMILY SSF55821 3 203 6.64E-86 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CIG75_RS03685 46b38ba663c040b7e7648b738c8af4fd 400 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 2 204 39.692 T 28-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CIG75_RS03685 46b38ba663c040b7e7648b738c8af4fd 400 Pfam PF00925 GTP cyclohydrolase II 210 373 1.3E-76 T 28-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CIG75_RS03685 46b38ba663c040b7e7648b738c8af4fd 400 Gene3D G3DSA:3.90.870.10 1 213 8.2E-95 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CIG75_RS03685 46b38ba663c040b7e7648b738c8af4fd 400 PIRSF PIRSF001259 2 400 2.4E-187 T 28-03-2018 CIG75_RS03685 46b38ba663c040b7e7648b738c8af4fd 400 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 205 400 42.868 T 28-03-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CIG75_RS03685 46b38ba663c040b7e7648b738c8af4fd 400 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 210 398 3.5E-83 T 28-03-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CIG75_RS03685 46b38ba663c040b7e7648b738c8af4fd 400 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 8 199 1.8E-84 T 28-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CIG75_RS03685 46b38ba663c040b7e7648b738c8af4fd 400 SUPERFAMILY SSF142695 206 377 3.4E-74 T 28-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CIG75_RS03685 46b38ba663c040b7e7648b738c8af4fd 400 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 4 200 7.1E-80 T 28-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CIG75_RS03685 46b38ba663c040b7e7648b738c8af4fd 400 Hamap MF_01283 Riboflavin biosynthesis protein RibBA [ribBA]. 3 396 55.748 T 28-03-2018 IPR016299 Riboflavin biosynthesis protein RibBA GO:0009231 KEGG: 00740+3.5.4.25+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CIG75_RS07385 a5c4eb52a2b56e635a04d09a37fc03b4 104 Pfam PF08863 YolD-like protein 14 103 7.1E-11 T 28-03-2018 IPR014962 YolD-like protein CIG75_RS16070 ee554f609f79bfed0ba3e02c518d4f01 416 SUPERFAMILY SSF52467 336 411 4.36E-5 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CIG75_RS16070 ee554f609f79bfed0ba3e02c518d4f01 416 TIGRFAM TIGR00300 TIGR00300: TIGR00300 family protein 67 410 7.9E-129 T 28-03-2018 IPR005239 Conserved hypothetical protein CHP00300 CIG75_RS16070 ee554f609f79bfed0ba3e02c518d4f01 416 Gene3D G3DSA:3.40.50.10690 183 411 6.3E-93 T 28-03-2018 CIG75_RS16070 ee554f609f79bfed0ba3e02c518d4f01 416 Gene3D G3DSA:2.40.420.10 84 165 3.9E-26 T 28-03-2018 CIG75_RS04420 7c30f00e74ad509662cb48d6265a8c81 236 SMART SM00448 3 113 4.1E-48 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CIG75_RS04420 7c30f00e74ad509662cb48d6265a8c81 236 SMART SM00862 156 232 6.2E-26 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CIG75_RS04420 7c30f00e74ad509662cb48d6265a8c81 236 Gene3D G3DSA:3.40.50.2300 2 130 2.3E-41 T 28-03-2018 CIG75_RS04420 7c30f00e74ad509662cb48d6265a8c81 236 SUPERFAMILY SSF46894 132 232 3.97E-29 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CIG75_RS04420 7c30f00e74ad509662cb48d6265a8c81 236 Pfam PF00486 Transcriptional regulatory protein, C terminal 157 232 7.9E-24 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CIG75_RS04420 7c30f00e74ad509662cb48d6265a8c81 236 Gene3D G3DSA:1.10.10.10 131 235 1.2E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS04420 7c30f00e74ad509662cb48d6265a8c81 236 SUPERFAMILY SSF52172 3 124 2.99E-44 T 28-03-2018 IPR011006 CheY-like superfamily CIG75_RS04420 7c30f00e74ad509662cb48d6265a8c81 236 Pfam PF00072 Response regulator receiver domain 5 114 3.2E-31 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CIG75_RS14305 ec3f41932d24812af321c080bb33cf38 420 Pfam PF00860 Permease family 2 378 1.1E-57 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CIG75_RS09180 5d59ef78a804d57335f8a5fa7bfd0ac2 743 Gene3D G3DSA:3.40.50.300 10 277 7.6E-56 T 28-03-2018 CIG75_RS09180 5d59ef78a804d57335f8a5fa7bfd0ac2 743 Pfam PF13361 UvrD-like helicase C-terminal domain 282 615 3.2E-46 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CIG75_RS09180 5d59ef78a804d57335f8a5fa7bfd0ac2 743 Pfam PF00580 UvrD/REP helicase N-terminal domain 135 275 1.9E-35 T 28-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 CIG75_RS09180 5d59ef78a804d57335f8a5fa7bfd0ac2 743 Pfam PF00580 UvrD/REP helicase N-terminal domain 17 111 1.4E-24 T 28-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 CIG75_RS09180 5d59ef78a804d57335f8a5fa7bfd0ac2 743 SUPERFAMILY SSF52540 9 632 4.79E-136 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS09180 5d59ef78a804d57335f8a5fa7bfd0ac2 743 Gene3D G3DSA:3.40.50.300 278 636 1.2E-46 T 28-03-2018 CIG75_RS05660 a6a3733565c26be42f468c5d39e85370 383 Gene3D G3DSA:1.10.580.10 307 362 9.3E-12 T 28-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain CIG75_RS05660 a6a3733565c26be42f468c5d39e85370 383 PRINTS PR00143 Citrate synthase signature 129 142 4.3E-39 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CIG75_RS05660 a6a3733565c26be42f468c5d39e85370 383 PRINTS PR00143 Citrate synthase signature 315 331 4.3E-39 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CIG75_RS05660 a6a3733565c26be42f468c5d39e85370 383 PRINTS PR00143 Citrate synthase signature 200 228 4.3E-39 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CIG75_RS05660 a6a3733565c26be42f468c5d39e85370 383 PRINTS PR00143 Citrate synthase signature 178 193 4.3E-39 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CIG75_RS05660 a6a3733565c26be42f468c5d39e85370 383 PRINTS PR00143 Citrate synthase signature 253 273 4.3E-39 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CIG75_RS05660 a6a3733565c26be42f468c5d39e85370 383 PRINTS PR00143 Citrate synthase signature 335 349 4.3E-39 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CIG75_RS05660 a6a3733565c26be42f468c5d39e85370 383 Pfam PF00285 Citrate synthase, C-terminal domain 9 364 3.1E-121 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CIG75_RS05660 a6a3733565c26be42f468c5d39e85370 383 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 9 382 5.4E-150 T 28-03-2018 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 CIG75_RS05660 a6a3733565c26be42f468c5d39e85370 383 PIRSF PIRSF001369 1 383 2.2E-134 T 28-03-2018 IPR024176 Citrate synthase, bacterial-type CIG75_RS05660 a6a3733565c26be42f468c5d39e85370 383 SUPERFAMILY SSF48256 8 382 1.44E-125 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CIG75_RS05660 a6a3733565c26be42f468c5d39e85370 383 ProSitePatterns PS00480 Citrate synthase signature. 260 272 - T 28-03-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 CIG75_RS05660 a6a3733565c26be42f468c5d39e85370 383 Gene3D G3DSA:1.10.580.10 1 257 3.9E-85 T 28-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain CIG75_RS08805 69946d24786319e613da830c2eabdfeb 265 Pfam PF11167 Protein of unknown function (DUF2953) 176 227 1.1E-13 T 28-03-2018 IPR021338 Protein of unknown function DUF2953 CIG75_RS07325 8987e42f34a22dad8a1c67753736c470 328 Gene3D G3DSA:3.30.1220.10 229 328 7.2E-9 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CIG75_RS07325 8987e42f34a22dad8a1c67753736c470 328 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 7 188 7.0E-45 T 28-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain CIG75_RS07325 8987e42f34a22dad8a1c67753736c470 328 SMART SM00833 240 327 4.3E-7 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CIG75_RS07325 8987e42f34a22dad8a1c67753736c470 328 SUPERFAMILY SSF52540 5 191 3.13E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS07325 8987e42f34a22dad8a1c67753736c470 328 SUPERFAMILY SSF90002 241 326 1.27E-9 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CIG75_RS07325 8987e42f34a22dad8a1c67753736c470 328 Gene3D G3DSA:3.40.50.300 3 207 2.3E-36 T 28-03-2018 CIG75_RS07325 8987e42f34a22dad8a1c67753736c470 328 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 241 326 2.0E-10 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CIG75_RS07370 d40a5332ee7b5451f81d77ef47ac0867 220 SUPERFAMILY SSF55729 37 204 1.32E-35 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CIG75_RS07370 d40a5332ee7b5451f81d77ef47ac0867 220 Pfam PF13302 Acetyltransferase (GNAT) domain 37 178 3.4E-24 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CIG75_RS07370 d40a5332ee7b5451f81d77ef47ac0867 220 Gene3D G3DSA:3.40.630.30 33 217 4.6E-32 T 28-03-2018 CIG75_RS15990 65b9b2c357119e3aab0aeead3ee0507e 433 Gene3D G3DSA:3.30.830.10 9 231 7.4E-49 T 28-03-2018 CIG75_RS15990 65b9b2c357119e3aab0aeead3ee0507e 433 SUPERFAMILY SSF63411 23 226 3.51E-42 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CIG75_RS15990 65b9b2c357119e3aab0aeead3ee0507e 433 SUPERFAMILY SSF63411 262 432 3.83E-17 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CIG75_RS15990 65b9b2c357119e3aab0aeead3ee0507e 433 Pfam PF05193 Peptidase M16 inactive domain 189 366 1.1E-15 T 28-03-2018 IPR007863 Peptidase M16, C-terminal CIG75_RS15990 65b9b2c357119e3aab0aeead3ee0507e 433 Gene3D G3DSA:3.30.830.10 232 433 1.4E-18 T 28-03-2018 CIG75_RS15990 65b9b2c357119e3aab0aeead3ee0507e 433 Pfam PF00675 Insulinase (Peptidase family M16) 69 182 8.2E-16 T 28-03-2018 IPR011765 Peptidase M16, N-terminal CIG75_RS14120 0abf69d9060c5a9c8aff2c70c008a0aa 417 Pfam PF07690 Major Facilitator Superfamily 29 353 1.5E-14 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CIG75_RS14120 0abf69d9060c5a9c8aff2c70c008a0aa 417 Gene3D G3DSA:1.20.1250.20 207 408 6.4E-6 T 28-03-2018 CIG75_RS14120 0abf69d9060c5a9c8aff2c70c008a0aa 417 SUPERFAMILY SSF103473 18 404 1.01E-31 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS14120 0abf69d9060c5a9c8aff2c70c008a0aa 417 Gene3D G3DSA:1.20.1250.20 14 206 1.9E-17 T 28-03-2018 CIG75_RS15475 861b1f49d89202d12389e5b67d085ec4 119 Pfam PF03960 ArsC family 42 116 2.7E-16 T 28-03-2018 IPR006660 Arsenate reductase-like CIG75_RS15475 861b1f49d89202d12389e5b67d085ec4 119 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 6 117 1.5E-34 T 28-03-2018 IPR006504 Transcriptional regulator Spx/MgsR CIG75_RS15475 861b1f49d89202d12389e5b67d085ec4 119 Gene3D G3DSA:3.40.30.10 3 118 7.6E-36 T 28-03-2018 CIG75_RS15475 861b1f49d89202d12389e5b67d085ec4 119 SUPERFAMILY SSF52833 8 118 2.06E-33 T 28-03-2018 IPR012336 Thioredoxin-like fold CIG75_RS20210 7d308e078b4b1ea33ef3c80e14a1a465 167 SMART SM00316 4 74 1.6E-26 T 28-03-2018 IPR022967 RNA-binding domain, S1 CIG75_RS20210 7d308e078b4b1ea33ef3c80e14a1a465 167 Gene3D G3DSA:2.40.50.140 7 159 4.0E-26 T 28-03-2018 CIG75_RS20210 7d308e078b4b1ea33ef3c80e14a1a465 167 SUPERFAMILY SSF50249 4 79 2.07E-23 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CIG75_RS20210 7d308e078b4b1ea33ef3c80e14a1a465 167 Pfam PF00575 S1 RNA binding domain 5 74 1.3E-20 T 28-03-2018 IPR003029 S1 domain GO:0003676 CIG75_RS06225 72d2352def9a24bc390f07fc4f43b4e8 392 Pfam PF13535 ATP-grasp domain 121 279 1.9E-54 T 28-03-2018 CIG75_RS06225 72d2352def9a24bc390f07fc4f43b4e8 392 Gene3D G3DSA:3.30.470.20 14 309 1.0E-18 T 28-03-2018 CIG75_RS06225 72d2352def9a24bc390f07fc4f43b4e8 392 SUPERFAMILY SSF56059 66 295 3.73E-20 T 28-03-2018 CIG75_RS14870 c4a4874f503693167e15d2433f8235cf 390 TIGRFAM TIGR02867 spore_II_P: stage II sporulation protein P 175 372 4.6E-53 T 28-03-2018 IPR010897 Sporulation stage II, protein P CIG75_RS14870 c4a4874f503693167e15d2433f8235cf 390 Pfam PF07454 Stage II sporulation protein P (SpoIIP) 165 366 2.4E-56 T 28-03-2018 IPR010897 Sporulation stage II, protein P CIG75_RS14870 c4a4874f503693167e15d2433f8235cf 390 Gene3D G3DSA:3.40.630.40 169 381 1.5E-7 T 28-03-2018 CIG75_RS11205 2b2173f0beb763ca214da55ad43f1c44 1019 Pfam PF04865 Baseplate J-like protein 766 924 4.6E-11 T 28-03-2018 IPR006949 Baseplate protein J-like CIG75_RS03610 10177b80740de5d68c09f551b7358fbc 762 SUPERFAMILY SSF53187 38 300 6.83E-55 T 28-03-2018 CIG75_RS03610 10177b80740de5d68c09f551b7358fbc 762 Pfam PF04389 Peptidase family M28 105 294 1.5E-43 T 28-03-2018 IPR007484 Peptidase M28 CIG75_RS03610 10177b80740de5d68c09f551b7358fbc 762 Gene3D G3DSA:3.40.630.10 29 301 4.7E-52 T 28-03-2018 CIG75_RS01525 ba9d93a5d4b8bc802004ad1ad9520b92 126 Pfam PF13673 Acetyltransferase (GNAT) domain 8 95 1.1E-12 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CIG75_RS01525 ba9d93a5d4b8bc802004ad1ad9520b92 126 SUPERFAMILY SSF55729 3 124 4.05E-24 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CIG75_RS01525 ba9d93a5d4b8bc802004ad1ad9520b92 126 Gene3D G3DSA:3.40.630.30 1 126 2.5E-22 T 28-03-2018 CIG75_RS18015 db4fb088b677d9457d215cb339162ef6 271 SUPERFAMILY SSF53474 8 270 8.31E-62 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS18015 db4fb088b677d9457d215cb339162ef6 271 Gene3D G3DSA:3.40.50.1820 3 271 6.5E-48 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS18015 db4fb088b677d9457d215cb339162ef6 271 PRINTS PR00412 Epoxide hydrolase signature 30 48 7.4E-5 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CIG75_RS18015 db4fb088b677d9457d215cb339162ef6 271 PRINTS PR00412 Epoxide hydrolase signature 212 228 7.4E-5 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CIG75_RS18015 db4fb088b677d9457d215cb339162ef6 271 PRINTS PR00412 Epoxide hydrolase signature 246 268 7.4E-5 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CIG75_RS18015 db4fb088b677d9457d215cb339162ef6 271 Pfam PF12697 Alpha/beta hydrolase family 26 261 4.2E-24 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CIG75_RS18015 db4fb088b677d9457d215cb339162ef6 271 PRINTS PR00111 Alpha/beta hydrolase fold signature 49 64 4.3E-13 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CIG75_RS18015 db4fb088b677d9457d215cb339162ef6 271 PRINTS PR00111 Alpha/beta hydrolase fold signature 214 228 4.3E-13 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CIG75_RS18015 db4fb088b677d9457d215cb339162ef6 271 PRINTS PR00111 Alpha/beta hydrolase fold signature 94 107 4.3E-13 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CIG75_RS18015 db4fb088b677d9457d215cb339162ef6 271 PRINTS PR00111 Alpha/beta hydrolase fold signature 108 121 4.3E-13 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CIG75_RS17380 2a6cb0977dc057efd913de99217ce1f9 956 Gene3D G3DSA:3.40.50.300 395 615 2.1E-26 T 28-03-2018 CIG75_RS17380 2a6cb0977dc057efd913de99217ce1f9 956 Hamap MF_00205 UvrABC system protein A [uvrA]. 3 939 23.232 T 28-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 CIG75_RS17380 2a6cb0977dc057efd913de99217ce1f9 956 Gene3D G3DSA:3.40.50.300 616 952 9.3E-55 T 28-03-2018 CIG75_RS17380 2a6cb0977dc057efd913de99217ce1f9 956 Gene3D G3DSA:3.40.50.300 39 138 0.0017 T 28-03-2018 CIG75_RS17380 2a6cb0977dc057efd913de99217ce1f9 956 ProSitePatterns PS00211 ABC transporters family signature. 829 843 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS17380 2a6cb0977dc057efd913de99217ce1f9 956 ProSitePatterns PS00211 ABC transporters family signature. 488 502 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS17380 2a6cb0977dc057efd913de99217ce1f9 956 Gene3D G3DSA:3.40.50.300 6 38 0.002 T 28-03-2018 CIG75_RS17380 2a6cb0977dc057efd913de99217ce1f9 956 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 5 924 0.0 T 28-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 CIG75_RS17380 2a6cb0977dc057efd913de99217ce1f9 956 Gene3D G3DSA:1.10.8.280 285 394 1.1E-39 T 28-03-2018 CIG75_RS17380 2a6cb0977dc057efd913de99217ce1f9 956 SUPERFAMILY SSF52540 453 570 2.21E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS17380 2a6cb0977dc057efd913de99217ce1f9 956 SUPERFAMILY SSF52540 10 207 2.21E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS17380 2a6cb0977dc057efd913de99217ce1f9 956 SUPERFAMILY SSF52540 615 912 1.77E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS17380 2a6cb0977dc057efd913de99217ce1f9 956 Pfam PF00005 ABC transporter 623 859 3.7E-9 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS17380 2a6cb0977dc057efd913de99217ce1f9 956 Gene3D G3DSA:3.30.190.20 139 248 8.7E-47 T 28-03-2018 CIG75_RS00505 04e6796a9a9efc5238bc66aa20d697ac 650 Gene3D G3DSA:3.30.230.10 447 650 5.0E-51 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CIG75_RS00505 04e6796a9a9efc5238bc66aa20d697ac 650 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 549 557 - T 28-03-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 CIG75_RS00505 04e6796a9a9efc5238bc66aa20d697ac 650 TIGRFAM TIGR02903 spore_lon_C: ATP-dependent protease, Lon family 28 640 5.0E-302 T 28-03-2018 IPR014252 Sporulation protease LonC CIG75_RS00505 04e6796a9a9efc5238bc66aa20d697ac 650 SUPERFAMILY SSF52540 165 315 1.68E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS00505 04e6796a9a9efc5238bc66aa20d697ac 650 SUPERFAMILY SSF52540 346 449 1.68E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS00505 04e6796a9a9efc5238bc66aa20d697ac 650 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 207 226 6.7E-29 T 28-03-2018 CIG75_RS00505 04e6796a9a9efc5238bc66aa20d697ac 650 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 471 487 6.7E-29 T 28-03-2018 CIG75_RS00505 04e6796a9a9efc5238bc66aa20d697ac 650 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 599 617 6.7E-29 T 28-03-2018 CIG75_RS00505 04e6796a9a9efc5238bc66aa20d697ac 650 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 576 595 6.7E-29 T 28-03-2018 CIG75_RS00505 04e6796a9a9efc5238bc66aa20d697ac 650 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 546 565 6.7E-29 T 28-03-2018 CIG75_RS00505 04e6796a9a9efc5238bc66aa20d697ac 650 SUPERFAMILY SSF54211 471 640 9.29E-45 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CIG75_RS00505 04e6796a9a9efc5238bc66aa20d697ac 650 Gene3D G3DSA:1.10.8.60 367 446 4.6E-9 T 28-03-2018 CIG75_RS00505 04e6796a9a9efc5238bc66aa20d697ac 650 Gene3D G3DSA:3.40.50.300 157 366 7.2E-33 T 28-03-2018 CIG75_RS00505 04e6796a9a9efc5238bc66aa20d697ac 650 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 203 375 1.1E-15 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CIG75_RS00505 04e6796a9a9efc5238bc66aa20d697ac 650 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 284 299 - T 28-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CIG75_RS00505 04e6796a9a9efc5238bc66aa20d697ac 650 SMART SM00382 199 378 4.7E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS00505 04e6796a9a9efc5238bc66aa20d697ac 650 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 460 640 2.1E-34 T 28-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 CIG75_RS05400 7042c064b27904fc6afa99d741a657ea 451 Pfam PF04293 SpoVR like protein 5 389 2.4E-150 T 28-03-2018 IPR007390 Sporulation stage V, protein R CIG75_RS05965 6cbf2c9945e4aa006eb56ea35a58e515 392 Gene3D G3DSA:1.10.10.690 162 238 2.7E-5 T 28-03-2018 CIG75_RS05965 6cbf2c9945e4aa006eb56ea35a58e515 392 Gene3D G3DSA:1.10.287.190 308 340 0.0033 T 28-03-2018 CIG75_RS05965 6cbf2c9945e4aa006eb56ea35a58e515 392 Gene3D G3DSA:1.10.287.190 99 134 0.24 T 28-03-2018 CIG75_RS05965 6cbf2c9945e4aa006eb56ea35a58e515 392 Gene3D G3DSA:1.10.3910.10 58 98 0.17 T 28-03-2018 CIG75_RS05965 6cbf2c9945e4aa006eb56ea35a58e515 392 Gene3D G3DSA:1.10.3910.10 267 307 0.16 T 28-03-2018 CIG75_RS13875 2303c19a1595709d9a36b9f613c92715 450 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 6 445 28.896 T 28-03-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 CIG75_RS13875 2303c19a1595709d9a36b9f613c92715 450 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 10 444 8.9E-146 T 28-03-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 CIG75_RS13875 2303c19a1595709d9a36b9f613c92715 450 Pfam PF02601 Exonuclease VII, large subunit 127 442 2.7E-97 T 28-03-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 CIG75_RS13875 2303c19a1595709d9a36b9f613c92715 450 Pfam PF13742 OB-fold nucleic acid binding domain 10 104 4.1E-27 T 28-03-2018 IPR025824 OB-fold nucleic acid binding domain GO:0003676 CIG75_RS13875 2303c19a1595709d9a36b9f613c92715 450 Gene3D G3DSA:2.40.50.140 4 105 3.5E-7 T 28-03-2018 CIG75_RS04510 47492dcdced1f0fdd5f9c6d7fc3c80f1 181 SUPERFAMILY SSF53254 2 179 3.44E-33 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CIG75_RS04510 47492dcdced1f0fdd5f9c6d7fc3c80f1 181 Gene3D G3DSA:3.40.50.1240 1 180 2.9E-32 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CIG75_RS04510 47492dcdced1f0fdd5f9c6d7fc3c80f1 181 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 169 8.3E-27 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CIG75_RS04510 47492dcdced1f0fdd5f9c6d7fc3c80f1 181 PIRSF PIRSF000709 2 160 0.0081 T 28-03-2018 CIG75_RS04510 47492dcdced1f0fdd5f9c6d7fc3c80f1 181 SMART SM00855 3 141 2.8E-6 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CIG75_RS05050 b39ad65ae934376a8790ed6a8e370a7e 210 Gene3D G3DSA:3.40.50.1950 18 207 1.3E-45 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CIG75_RS05050 b39ad65ae934376a8790ed6a8e370a7e 210 SUPERFAMILY SSF52507 25 203 9.81E-48 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CIG75_RS05050 b39ad65ae934376a8790ed6a8e370a7e 210 Pfam PF02441 Flavoprotein 26 198 1.3E-38 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CIG75_RS10510 7cb9d3736cc59d94a8fe73f4c66d0954 318 Pfam PF01569 PAP2 superfamily 196 269 1.5E-10 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CIG75_RS10510 7cb9d3736cc59d94a8fe73f4c66d0954 318 SMART SM00014 158 270 0.0088 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CIG75_RS10510 7cb9d3736cc59d94a8fe73f4c66d0954 318 Gene3D G3DSA:1.20.144.10 11 281 3.6E-8 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CIG75_RS10510 7cb9d3736cc59d94a8fe73f4c66d0954 318 SUPERFAMILY SSF48317 109 274 5.76E-10 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CIG75_RS05080 dae0801a586c88b93d963441fb4bc241 478 Gene3D G3DSA:3.40.309.10 265 458 2.3E-72 T 28-03-2018 CIG75_RS05080 dae0801a586c88b93d963441fb4bc241 478 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 276 287 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CIG75_RS05080 dae0801a586c88b93d963441fb4bc241 478 Gene3D G3DSA:3.40.605.10 1 264 2.4E-104 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CIG75_RS05080 dae0801a586c88b93d963441fb4bc241 478 Pfam PF00171 Aldehyde dehydrogenase family 15 472 1.3E-172 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CIG75_RS05080 dae0801a586c88b93d963441fb4bc241 478 TIGRFAM TIGR01780 SSADH: succinate-semialdehyde dehydrogenase 24 471 4.2E-201 T 28-03-2018 IPR010102 Succinate semialdehyde dehydrogenase GO:0009013|GO:0009450|GO:0055114 Reactome: R-HSA-916853 CIG75_RS05080 dae0801a586c88b93d963441fb4bc241 478 SUPERFAMILY SSF53720 6 474 1.57E-173 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CIG75_RS14235 1a4a5d40d6ef6a309792bf3aa3a92b5f 274 SUPERFAMILY SSF48239 34 178 3.53E-10 T 28-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CIG75_RS14235 1a4a5d40d6ef6a309792bf3aa3a92b5f 274 SUPERFAMILY SSF48239 228 270 3.53E-10 T 28-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CIG75_RS14235 1a4a5d40d6ef6a309792bf3aa3a92b5f 274 Gene3D G3DSA:1.50.10.20 30 274 1.1E-10 T 28-03-2018 CIG75_RS15145 0f4a0e5d5f2c29389ba56ca448ab34c1 424 TIGRFAM TIGR04267 mod_HExxH: HEXXH motif domain 233 405 1.5E-26 T 28-03-2018 IPR026337 HEXXH motif domain CIG75_RS07640 92e1f5419d14a0c45e3cb19d46348ef5 168 SUPERFAMILY SSF46626 19 161 4.3E-20 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CIG75_RS07640 92e1f5419d14a0c45e3cb19d46348ef5 168 Gene3D G3DSA:1.10.760.10 38 168 6.2E-22 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CIG75_RS07640 92e1f5419d14a0c45e3cb19d46348ef5 168 Pfam PF02433 Cytochrome C oxidase, mono-heme subunit/FixO 5 151 7.5E-34 T 28-03-2018 IPR003468 Cytochrome c oxidase, monohaem subunit/FixO CIG75_RS11115 de6802aa4e43277176ae96cd94b06c1e 417 SUPERFAMILY SSF103473 22 409 2.75E-44 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS11115 de6802aa4e43277176ae96cd94b06c1e 417 Gene3D G3DSA:1.20.1250.20 13 225 9.5E-24 T 28-03-2018 CIG75_RS11115 de6802aa4e43277176ae96cd94b06c1e 417 Gene3D G3DSA:1.20.1250.20 226 410 1.1E-19 T 28-03-2018 CIG75_RS11115 de6802aa4e43277176ae96cd94b06c1e 417 Pfam PF07690 Major Facilitator Superfamily 29 291 2.7E-19 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CIG75_RS05840 b83760f23fa5c204578e3735ade1e43a 223 SUPERFAMILY SSF52540 13 214 1.37E-19 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS05840 b83760f23fa5c204578e3735ade1e43a 223 Gene3D G3DSA:3.40.50.300 4 223 3.4E-17 T 28-03-2018 CIG75_RS17570 4b90dc036200d45a9993888ee4e2af0f 395 Pfam PF02687 FtsX-like permease family 301 388 1.1E-14 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CIG75_RS17570 4b90dc036200d45a9993888ee4e2af0f 395 Pfam PF12704 MacB-like periplasmic core domain 21 231 1.2E-25 T 28-03-2018 IPR025857 MacB-like periplasmic core domain CIG75_RS01745 6586483976ec76a225034ba6b9975335 236 Gene3D G3DSA:3.30.70.250 3 86 3.6E-37 T 28-03-2018 CIG75_RS01745 6586483976ec76a225034ba6b9975335 236 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 174 202 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CIG75_RS01745 6586483976ec76a225034ba6b9975335 236 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 91 118 1.6E-4 T 28-03-2018 IPR001451 Hexapeptide repeat CIG75_RS01745 6586483976ec76a225034ba6b9975335 236 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 121 156 7.6E-8 T 28-03-2018 IPR001451 Hexapeptide repeat CIG75_RS01745 6586483976ec76a225034ba6b9975335 236 TIGRFAM TIGR03532 DapD_Ac: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase 6 236 1.0E-117 T 28-03-2018 IPR019873 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, DapH GO:0009089|GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 CIG75_RS01745 6586483976ec76a225034ba6b9975335 236 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 165 200 2.8E-11 T 28-03-2018 IPR001451 Hexapeptide repeat CIG75_RS01745 6586483976ec76a225034ba6b9975335 236 SUPERFAMILY SSF51161 89 225 8.04E-49 T 28-03-2018 IPR011004 Trimeric LpxA-like CIG75_RS01745 6586483976ec76a225034ba6b9975335 236 Hamap MF_01691 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase [dapH]. 1 235 45.934 T 28-03-2018 IPR019873 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, DapH GO:0009089|GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 CIG75_RS01745 6586483976ec76a225034ba6b9975335 236 Pfam PF08503 Tetrahydrodipicolinate succinyltransferase N-terminal 4 87 3.1E-34 T 28-03-2018 IPR013710 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, N-terminal GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 CIG75_RS01745 6586483976ec76a225034ba6b9975335 236 Gene3D G3DSA:2.160.10.10 87 236 1.1E-43 T 28-03-2018 CIG75_RS05990 6a20c89be886aa32c079d29c3a905463 65 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 28-03-2018 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS05990 6a20c89be886aa32c079d29c3a905463 65 SUPERFAMILY SSF143034 3 64 2.22E-20 T 28-03-2018 CIG75_RS05990 6a20c89be886aa32c079d29c3a905463 65 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 17.216 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CIG75_RS05990 6a20c89be886aa32c079d29c3a905463 65 PRINTS PR00064 Ribosomal protein L35 signature 3 20 5.2E-18 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CIG75_RS05990 6a20c89be886aa32c079d29c3a905463 65 PRINTS PR00064 Ribosomal protein L35 signature 21 35 5.2E-18 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CIG75_RS05990 6a20c89be886aa32c079d29c3a905463 65 PRINTS PR00064 Ribosomal protein L35 signature 36 54 5.2E-18 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CIG75_RS05990 6a20c89be886aa32c079d29c3a905463 65 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 3 64 1.5E-23 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CIG75_RS05990 6a20c89be886aa32c079d29c3a905463 65 Pfam PF01632 Ribosomal protein L35 3 62 8.7E-22 T 28-03-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS00400 0f9e69b873826be3183877e7bd4f7a23 418 Pfam PF08281 Sigma-70, region 4 117 167 3.2E-8 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS00400 0f9e69b873826be3183877e7bd4f7a23 418 Gene3D G3DSA:1.10.10.10 72 170 3.3E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS00400 0f9e69b873826be3183877e7bd4f7a23 418 Pfam PF04542 Sigma-70 region 2 20 79 7.1E-12 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS00400 0f9e69b873826be3183877e7bd4f7a23 418 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 168 7.6E-15 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS00400 0f9e69b873826be3183877e7bd4f7a23 418 Gene3D G3DSA:1.10.1740.10 4 71 5.4E-14 T 28-03-2018 CIG75_RS00400 0f9e69b873826be3183877e7bd4f7a23 418 SUPERFAMILY SSF88946 13 97 2.35E-13 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS00400 0f9e69b873826be3183877e7bd4f7a23 418 SUPERFAMILY SSF88659 108 168 3.92E-11 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS03220 98d4f1fbd76eb93808cc49b3491585f2 125 SUPERFAMILY SSF88659 73 120 2.06E-9 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS03220 98d4f1fbd76eb93808cc49b3491585f2 125 Pfam PF08281 Sigma-70, region 4 74 115 1.1E-6 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS03220 98d4f1fbd76eb93808cc49b3491585f2 125 Gene3D G3DSA:1.10.10.10 22 124 2.8E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS18565 ef2d809bbddcadb790b3ae4065e101bc 395 Pfam PF07690 Major Facilitator Superfamily 35 355 6.7E-19 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CIG75_RS18565 ef2d809bbddcadb790b3ae4065e101bc 395 SUPERFAMILY SSF103473 21 392 1.06E-37 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS18565 ef2d809bbddcadb790b3ae4065e101bc 395 Gene3D G3DSA:1.20.1250.20 7 200 3.1E-17 T 28-03-2018 CIG75_RS18565 ef2d809bbddcadb790b3ae4065e101bc 395 Gene3D G3DSA:1.20.1250.20 203 388 5.6E-15 T 28-03-2018 CIG75_RS18565 ef2d809bbddcadb790b3ae4065e101bc 395 ProSitePatterns PS00216 Sugar transport proteins signature 1. 61 78 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CIG75_RS08815 d868ab4c26c15e86292e8b0fe4220623 396 SUPERFAMILY SSF56601 1 286 1.1E-70 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CIG75_RS08815 d868ab4c26c15e86292e8b0fe4220623 396 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 46 272 1.0E-64 T 28-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 CIG75_RS08815 d868ab4c26c15e86292e8b0fe4220623 396 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 154 167 1.6E-15 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CIG75_RS08815 d868ab4c26c15e86292e8b0fe4220623 396 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 78 89 1.6E-15 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CIG75_RS08815 d868ab4c26c15e86292e8b0fe4220623 396 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 127 144 1.6E-15 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CIG75_RS08815 d868ab4c26c15e86292e8b0fe4220623 396 Gene3D G3DSA:3.40.710.10 35 287 1.6E-49 T 28-03-2018 CIG75_RS08815 d868ab4c26c15e86292e8b0fe4220623 396 Gene3D G3DSA:2.60.410.10 289 379 9.0E-20 T 28-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CIG75_RS08815 d868ab4c26c15e86292e8b0fe4220623 396 SUPERFAMILY SSF69189 281 377 6.47E-16 T 28-03-2018 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CIG75_RS08815 d868ab4c26c15e86292e8b0fe4220623 396 SMART SM00936 289 379 8.6E-18 T 28-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CIG75_RS08815 d868ab4c26c15e86292e8b0fe4220623 396 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 294 379 1.6E-18 T 28-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CIG75_RS01470 78e0512809cd7271078b15476b92ffdf 133 Gene3D G3DSA:3.10.450.100 33 133 4.8E-6 T 28-03-2018 CIG75_RS01470 78e0512809cd7271078b15476b92ffdf 133 Pfam PF12870 Domain of unknown function (DUF4878) 31 127 2.9E-12 T 28-03-2018 IPR024267 Domain of unknown function (DUF4878) CIG75_RS06655 87ad2cf31b7dd4c4232cddaeefd7508a 415 Gene3D G3DSA:3.20.20.30 68 409 1.8E-56 T 28-03-2018 CIG75_RS06655 87ad2cf31b7dd4c4232cddaeefd7508a 415 Pfam PF00296 Luciferase-like monooxygenase 70 384 8.6E-42 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CIG75_RS06655 87ad2cf31b7dd4c4232cddaeefd7508a 415 TIGRFAM TIGR04020 seco_metab_LLM: natural product biosynthesis luciferase-like monooxygenase domain 72 410 1.2E-137 T 28-03-2018 IPR024011 Natural product biosynthesis luciferase-like monooxygenase domain CIG75_RS06655 87ad2cf31b7dd4c4232cddaeefd7508a 415 SUPERFAMILY SSF51679 70 408 1.96E-65 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CIG75_RS16770 c4dc31ab91378b72256d85d92d179303 163 SUPERFAMILY SSF54637 9 156 3.58E-46 T 28-03-2018 IPR029069 HotDog domain CIG75_RS16770 c4dc31ab91378b72256d85d92d179303 163 Gene3D G3DSA:3.10.129.10 2 158 2.4E-49 T 28-03-2018 CIG75_RS16770 c4dc31ab91378b72256d85d92d179303 163 Pfam PF03061 Thioesterase superfamily 28 99 2.8E-14 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CIG75_RS12385 4403373ca0315e64d2c69810631ebb20 58 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 56 5.1E-29 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS12385 4403373ca0315e64d2c69810631ebb20 58 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 55 20.471 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS12385 4403373ca0315e64d2c69810631ebb20 58 SUPERFAMILY SSF57829 1 56 3.36E-23 T 28-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 CIG75_RS12385 4403373ca0315e64d2c69810631ebb20 58 Pfam PF01783 Ribosomal L32p protein family 2 56 4.4E-27 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS05825 d0b306b04107a45f1f176657c42c17ac 329 SUPERFAMILY SSF56300 2 245 7.33E-30 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CIG75_RS05825 d0b306b04107a45f1f176657c42c17ac 329 Gene3D G3DSA:3.60.21.10 1 251 1.6E-28 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CIG75_RS05825 d0b306b04107a45f1f176657c42c17ac 329 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 2 236 3.0E-11 T 28-03-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 CIG75_RS00200 095b7b632d7b4f1017b5e487c5d4ad52 83 Pfam PF04025 Domain of unknown function (DUF370) 2 75 5.4E-14 T 28-03-2018 IPR007169 Uncharacterised protein family UPF0296 CIG75_RS01280 3e473ec844b951527347e3cc5466739e 483 SUPERFAMILY SSF103473 84 476 1.83E-51 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS01280 3e473ec844b951527347e3cc5466739e 483 Pfam PF07690 Major Facilitator Superfamily 91 411 4.3E-29 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CIG75_RS01280 3e473ec844b951527347e3cc5466739e 483 Gene3D G3DSA:1.20.1250.20 70 274 3.4E-26 T 28-03-2018 CIG75_RS01280 3e473ec844b951527347e3cc5466739e 483 Gene3D G3DSA:1.20.1250.20 288 479 2.8E-20 T 28-03-2018 CIG75_RS14150 84998d82296595516daf52e980f77253 487 Gene3D G3DSA:3.60.120.10 18 485 2.9E-129 T 28-03-2018 IPR005801 ADC synthase GO:0009058 CIG75_RS14150 84998d82296595516daf52e980f77253 487 Pfam PF00425 chorismate binding enzyme 215 469 9.5E-90 T 28-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal CIG75_RS14150 84998d82296595516daf52e980f77253 487 PRINTS PR00095 Anthranilate synthase component I signature 411 425 1.6E-19 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CIG75_RS14150 84998d82296595516daf52e980f77253 487 PRINTS PR00095 Anthranilate synthase component I signature 331 344 1.6E-19 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CIG75_RS14150 84998d82296595516daf52e980f77253 487 PRINTS PR00095 Anthranilate synthase component I signature 426 440 1.6E-19 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CIG75_RS14150 84998d82296595516daf52e980f77253 487 PRINTS PR00095 Anthranilate synthase component I signature 317 330 1.6E-19 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CIG75_RS14150 84998d82296595516daf52e980f77253 487 Pfam PF04715 Anthranilate synthase component I, N terminal region 21 164 1.9E-13 T 28-03-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CIG75_RS14150 84998d82296595516daf52e980f77253 487 SUPERFAMILY SSF56322 16 477 1.28E-124 T 28-03-2018 IPR005801 ADC synthase GO:0009058 CIG75_RS15460 b5e6f5f2588fcc0ec10101afba0575b3 616 PIRSF PIRSF005091 3 615 8.1E-122 T 28-03-2018 IPR012160 Lipoteichoic acid synthase-like CIG75_RS15460 b5e6f5f2588fcc0ec10101afba0575b3 616 SUPERFAMILY SSF53649 233 544 2.94E-57 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CIG75_RS15460 b5e6f5f2588fcc0ec10101afba0575b3 616 Pfam PF00884 Sulfatase 235 526 4.8E-36 T 28-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 CIG75_RS15460 b5e6f5f2588fcc0ec10101afba0575b3 616 Gene3D G3DSA:3.40.720.10 230 536 8.9E-41 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CIG75_RS17665 f7490789c66ca44522b0ca2b0c5ddb38 361 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 23 331 5.5E-135 T 28-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CIG75_RS17665 f7490789c66ca44522b0ca2b0c5ddb38 361 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 24 327 1.4E-106 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CIG75_RS17665 f7490789c66ca44522b0ca2b0c5ddb38 361 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 173 194 5.4E-47 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CIG75_RS17665 f7490789c66ca44522b0ca2b0c5ddb38 361 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 117 136 5.4E-47 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CIG75_RS17665 f7490789c66ca44522b0ca2b0c5ddb38 361 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 24 37 5.4E-47 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CIG75_RS17665 f7490789c66ca44522b0ca2b0c5ddb38 361 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 284 293 5.4E-47 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CIG75_RS17665 f7490789c66ca44522b0ca2b0c5ddb38 361 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 96 116 5.4E-47 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CIG75_RS17665 f7490789c66ca44522b0ca2b0c5ddb38 361 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 150 162 5.4E-47 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CIG75_RS17665 f7490789c66ca44522b0ca2b0c5ddb38 361 SUPERFAMILY SSF53067 23 141 1.62E-30 T 28-03-2018 CIG75_RS17665 f7490789c66ca44522b0ca2b0c5ddb38 361 SUPERFAMILY SSF53067 121 329 5.48E-43 T 28-03-2018 CIG75_RS17665 f7490789c66ca44522b0ca2b0c5ddb38 361 Gene3D G3DSA:3.30.420.40 166 310 1.5E-20 T 28-03-2018 CIG75_RS17665 f7490789c66ca44522b0ca2b0c5ddb38 361 Pfam PF00814 Glycoprotease family 43 327 2.3E-100 T 28-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CIG75_RS17665 f7490789c66ca44522b0ca2b0c5ddb38 361 Gene3D G3DSA:3.30.420.40 21 165 3.9E-42 T 28-03-2018 CIG75_RS17665 f7490789c66ca44522b0ca2b0c5ddb38 361 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 21 352 62.067 T 28-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CIG75_RS01290 51de7c2eeed31a66fd49677f2da9bafe 438 Pfam PF03471 Transporter associated domain 358 432 2.4E-20 T 28-03-2018 IPR005170 Transporter-associated domain CIG75_RS01290 51de7c2eeed31a66fd49677f2da9bafe 438 SMART SM00116 293 341 0.83 T 28-03-2018 IPR000644 CBS domain CIG75_RS01290 51de7c2eeed31a66fd49677f2da9bafe 438 SMART SM00116 231 280 0.035 T 28-03-2018 IPR000644 CBS domain CIG75_RS01290 51de7c2eeed31a66fd49677f2da9bafe 438 Gene3D G3DSA:3.20.20.70 162 352 2.0E-35 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CIG75_RS01290 51de7c2eeed31a66fd49677f2da9bafe 438 Pfam PF00571 CBS domain 292 341 3.6E-7 T 28-03-2018 IPR000644 CBS domain CIG75_RS01290 51de7c2eeed31a66fd49677f2da9bafe 438 Pfam PF00571 CBS domain 223 276 4.8E-7 T 28-03-2018 IPR000644 CBS domain CIG75_RS01290 51de7c2eeed31a66fd49677f2da9bafe 438 Gene3D G3DSA:3.30.465.10 353 434 3.1E-25 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CIG75_RS01290 51de7c2eeed31a66fd49677f2da9bafe 438 SMART SM01091 356 434 4.5E-25 T 28-03-2018 IPR005170 Transporter-associated domain CIG75_RS01290 51de7c2eeed31a66fd49677f2da9bafe 438 SUPERFAMILY SSF56176 354 436 1.34E-20 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CIG75_RS01290 51de7c2eeed31a66fd49677f2da9bafe 438 Pfam PF01595 Domain of unknown function DUF21 14 207 6.3E-52 T 28-03-2018 IPR002550 Domain of unknown function DUF21 CIG75_RS01290 51de7c2eeed31a66fd49677f2da9bafe 438 SUPERFAMILY SSF54631 217 360 1.64E-33 T 28-03-2018 CIG75_RS11620 1405afb9efaf26a9621f3305a0819e36 270 Pfam PF13413 Helix-turn-helix domain 8 68 4.5E-23 T 28-03-2018 CIG75_RS11620 1405afb9efaf26a9621f3305a0819e36 270 SMART SM00530 7 68 0.0037 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS11620 1405afb9efaf26a9621f3305a0819e36 270 Gene3D G3DSA:1.10.260.40 1 83 2.1E-9 T 28-03-2018 CIG75_RS11620 1405afb9efaf26a9621f3305a0819e36 270 SUPERFAMILY SSF47413 3 70 5.12E-5 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CIG75_RS11620 1405afb9efaf26a9621f3305a0819e36 270 Pfam PF13464 Domain of unknown function (DUF4115) 197 257 3.2E-14 T 28-03-2018 IPR025194 Domain of unknown function DUF4115 CIG75_RS03300 bd367698d7f3bc251643d016bbd24c8f 406 SUPERFAMILY SSF56059 105 309 5.48E-24 T 28-03-2018 CIG75_RS03300 bd367698d7f3bc251643d016bbd24c8f 406 Pfam PF02655 ATP-grasp domain 137 275 5.8E-7 T 28-03-2018 IPR003806 ATP-grasp fold, DUF201-type GO:0005524|GO:0046872 CIG75_RS03300 bd367698d7f3bc251643d016bbd24c8f 406 Gene3D G3DSA:3.30.470.20 98 386 1.8E-27 T 28-03-2018 CIG75_RS07165 8be53eca67acf4eb7c393d494649a3ef 293 PIRSF PIRSF000103 1 293 1.4E-92 T 28-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CIG75_RS07165 8be53eca67acf4eb7c393d494649a3ef 293 Gene3D G3DSA:1.10.1040.10 165 292 4.1E-31 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CIG75_RS07165 8be53eca67acf4eb7c393d494649a3ef 293 SUPERFAMILY SSF51735 4 164 2.75E-49 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS07165 8be53eca67acf4eb7c393d494649a3ef 293 Gene3D G3DSA:3.40.50.720 3 164 1.0E-34 T 28-03-2018 CIG75_RS07165 8be53eca67acf4eb7c393d494649a3ef 293 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 166 283 3.2E-29 T 28-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 CIG75_RS07165 8be53eca67acf4eb7c393d494649a3ef 293 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 5 163 8.0E-50 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CIG75_RS07165 8be53eca67acf4eb7c393d494649a3ef 293 SUPERFAMILY SSF48179 164 288 6.69E-34 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CIG75_RS00880 7e5307b3cd9bcd52fd92398ccaa979d3 315 Pfam PF00892 EamA-like transporter family 8 148 1.1E-9 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CIG75_RS00880 7e5307b3cd9bcd52fd92398ccaa979d3 315 Pfam PF00892 EamA-like transporter family 161 295 1.6E-17 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CIG75_RS00880 7e5307b3cd9bcd52fd92398ccaa979d3 315 SUPERFAMILY SSF103481 199 299 4.84E-12 T 28-03-2018 CIG75_RS19570 ddbb7f130e1d13fd57b9e998a24e15f6 131 SUPERFAMILY SSF54211 5 131 5.69E-46 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CIG75_RS19570 ddbb7f130e1d13fd57b9e998a24e15f6 131 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 1 131 33.619 T 28-03-2018 IPR023035 Ribosomal protein S9, bacterial/plastid CIG75_RS19570 ddbb7f130e1d13fd57b9e998a24e15f6 131 Pfam PF00380 Ribosomal protein S9/S16 10 131 6.0E-45 T 28-03-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 CIG75_RS19570 ddbb7f130e1d13fd57b9e998a24e15f6 131 Gene3D G3DSA:3.30.230.10 3 131 8.0E-49 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CIG75_RS19570 ddbb7f130e1d13fd57b9e998a24e15f6 131 ProSitePatterns PS00360 Ribosomal protein S9 signature. 70 88 - T 28-03-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 CIG75_RS04590 5782eb21f774c15d262ad31a8db19e98 72 Pfam PF11213 Protein of unknown function (DUF3006) 6 67 4.7E-23 T 28-03-2018 IPR021377 Protein of unknown function DUF3006 CIG75_RS06685 9771f2cd7cd90c6a824f4c1d29dc7e28 258 SUPERFAMILY SSF53474 6 250 5.15E-53 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS06685 9771f2cd7cd90c6a824f4c1d29dc7e28 258 Pfam PF00975 Thioesterase domain 23 246 1.2E-53 T 28-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CIG75_RS06685 9771f2cd7cd90c6a824f4c1d29dc7e28 258 Gene3D G3DSA:3.40.50.1820 2 254 1.2E-31 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS05270 d8557436d6aab4c7b2bd8765808bddcc 255 Pfam PF09911 Uncharacterized protein conserved in bacteria (DUF2140) 65 251 7.2E-24 T 28-03-2018 IPR018672 Protein of unknown function DUF2140 CIG75_RS17210 2123727b4e8036112677574bca118a67 196 Pfam PF12007 Protein of unknown function (DUF3501) 6 195 1.1E-57 T 28-03-2018 IPR021890 Protein of unknown function DUF3501 CIG75_RS00680 e3703ab33d184b6c353f0072bf4351f8 362 SMART SM00267 186 357 1.0E-44 T 28-03-2018 IPR000160 GGDEF domain CIG75_RS00680 e3703ab33d184b6c353f0072bf4351f8 362 Gene3D G3DSA:3.30.450.40 5 190 3.3E-20 T 28-03-2018 IPR029016 GAF domain-like CIG75_RS00680 e3703ab33d184b6c353f0072bf4351f8 362 SMART SM00065 23 166 8.0E-5 T 28-03-2018 IPR003018 GAF domain GO:0005515 CIG75_RS00680 e3703ab33d184b6c353f0072bf4351f8 362 Pfam PF13185 GAF domain 27 149 2.7E-10 T 28-03-2018 IPR003018 GAF domain GO:0005515 CIG75_RS00680 e3703ab33d184b6c353f0072bf4351f8 362 Gene3D G3DSA:3.30.70.270 191 357 1.1E-49 T 28-03-2018 CIG75_RS00680 e3703ab33d184b6c353f0072bf4351f8 362 SUPERFAMILY SSF55781 6 173 2.84E-20 T 28-03-2018 IPR029016 GAF domain-like CIG75_RS00680 e3703ab33d184b6c353f0072bf4351f8 362 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 196 356 7.1E-38 T 28-03-2018 IPR000160 GGDEF domain CIG75_RS00680 e3703ab33d184b6c353f0072bf4351f8 362 Pfam PF00990 Diguanylate cyclase, GGDEF domain 199 353 1.3E-38 T 28-03-2018 IPR000160 GGDEF domain CIG75_RS00680 e3703ab33d184b6c353f0072bf4351f8 362 SUPERFAMILY SSF55073 202 356 7.77E-43 T 28-03-2018 IPR029787 Nucleotide cyclase CIG75_RS05500 74993b5535f33c68c3d33e26d3b9fb89 82 Pfam PF11588 Protein of unknown function (DUF3243) 3 79 2.2E-34 T 28-03-2018 IPR021637 Protein of unknown function DUF3243 CIG75_RS05500 74993b5535f33c68c3d33e26d3b9fb89 82 PIRSF PIRSF004764 1 82 5.4E-29 T 28-03-2018 IPR024702 Uncharacterised conserved protein YmfJ CIG75_RS04935 03e78b9a08e241a72364bac390708dbb 150 SMART SM00347 33 134 1.9E-24 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CIG75_RS04935 03e78b9a08e241a72364bac390708dbb 150 Pfam PF01047 MarR family 40 98 2.1E-13 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CIG75_RS04935 03e78b9a08e241a72364bac390708dbb 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 58 74 1.3E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CIG75_RS04935 03e78b9a08e241a72364bac390708dbb 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 94 110 1.3E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CIG75_RS04935 03e78b9a08e241a72364bac390708dbb 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 75 90 1.3E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CIG75_RS04935 03e78b9a08e241a72364bac390708dbb 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 124 144 1.3E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CIG75_RS04935 03e78b9a08e241a72364bac390708dbb 150 ProSitePatterns PS01117 MarR-type HTH domain signature. 73 107 - T 28-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CIG75_RS04935 03e78b9a08e241a72364bac390708dbb 150 Gene3D G3DSA:1.10.10.10 7 150 3.7E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS04935 03e78b9a08e241a72364bac390708dbb 150 SUPERFAMILY SSF46785 7 149 4.82E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS13580 5f019ea26feee20b9460971e0febfcbc 304 Pfam PF00682 HMGL-like 9 282 2.2E-51 T 28-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 CIG75_RS13580 5f019ea26feee20b9460971e0febfcbc 304 SUPERFAMILY SSF51569 4 294 6.78E-72 T 28-03-2018 CIG75_RS13580 5f019ea26feee20b9460971e0febfcbc 304 Gene3D G3DSA:3.20.20.70 4 301 4.0E-101 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CIG75_RS04090 008ddd60cf2dcf5a971980c3515ee53f 149 SMART SM00195 5 143 0.0055 T 28-03-2018 IPR020422 Dual specificity protein phosphatase domain GO:0006470|GO:0008138 CIG75_RS04090 008ddd60cf2dcf5a971980c3515ee53f 149 Gene3D G3DSA:3.90.190.10 3 148 6.2E-19 T 28-03-2018 IPR029021 Protein-tyrosine phosphatase-like CIG75_RS04090 008ddd60cf2dcf5a971980c3515ee53f 149 SUPERFAMILY SSF52799 4 145 2.72E-18 T 28-03-2018 IPR029021 Protein-tyrosine phosphatase-like CIG75_RS04090 008ddd60cf2dcf5a971980c3515ee53f 149 Pfam PF00782 Dual specificity phosphatase, catalytic domain 20 142 6.4E-9 T 28-03-2018 IPR000340 Dual specificity phosphatase, catalytic domain GO:0008138|GO:0016311 CIG75_RS07415 fb207b63e0b58b094acf5c3c6ad37dd1 394 TIGRFAM TIGR03402 FeS_nifS: cysteine desulfurase NifS 4 383 8.2E-175 T 28-03-2018 IPR017772 Cysteine desulfurase NifS, bacterial/archaeal GO:0006520|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CIG75_RS07415 fb207b63e0b58b094acf5c3c6ad37dd1 394 Pfam PF00266 Aminotransferase class-V 4 366 1.1E-93 T 28-03-2018 IPR000192 Aminotransferase class V domain CIG75_RS07415 fb207b63e0b58b094acf5c3c6ad37dd1 394 PIRSF PIRSF005572 1 381 2.0E-139 T 28-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CIG75_RS07415 fb207b63e0b58b094acf5c3c6ad37dd1 394 SUPERFAMILY SSF53383 3 376 6.25E-116 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CIG75_RS07415 fb207b63e0b58b094acf5c3c6ad37dd1 394 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 193 212 - T 28-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site CIG75_RS07415 fb207b63e0b58b094acf5c3c6ad37dd1 394 Hamap MF_00331 Cysteine desulfurase IscS [iscS]. 1 392 50.948 T 28-03-2018 IPR010240 Cysteine desulfurase IscS GO:0030170|GO:0031071|GO:0044571 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250|Reactome: R-HSA-1362409|Reactome: R-HSA-947581 CIG75_RS07415 fb207b63e0b58b094acf5c3c6ad37dd1 394 Gene3D G3DSA:3.90.1150.10 263 381 3.7E-39 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CIG75_RS07415 fb207b63e0b58b094acf5c3c6ad37dd1 394 Gene3D G3DSA:3.40.640.10 12 255 2.8E-63 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CIG75_RS07390 b06ecf41b918b0ea62ca97c04bb2bc7e 223 Pfam PF09986 Uncharacterized protein conserved in bacteria (DUF2225) 7 215 1.1E-56 T 28-03-2018 IPR018708 Protein of unknown function DUF2225 CIG75_RS07390 b06ecf41b918b0ea62ca97c04bb2bc7e 223 Gene3D G3DSA:1.25.40.10 25 222 4.7E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS07390 b06ecf41b918b0ea62ca97c04bb2bc7e 223 SUPERFAMILY SSF48452 97 197 1.14E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS06580 2923364cb3f6e6689df74d5336af74fd 175 Gene3D G3DSA:3.40.630.30 1 175 8.9E-30 T 28-03-2018 CIG75_RS06580 2923364cb3f6e6689df74d5336af74fd 175 Pfam PF00583 Acetyltransferase (GNAT) family 36 149 2.7E-18 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CIG75_RS06580 2923364cb3f6e6689df74d5336af74fd 175 SUPERFAMILY SSF55729 7 175 4.29E-31 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CIG75_RS00570 187d6d510ffe07eac8fc0d576c7432ba 56 Pfam PF14116 YyzF-like protein 4 56 3.7E-17 T 28-03-2018 IPR025626 YyzF-like protein CIG75_RS00570 187d6d510ffe07eac8fc0d576c7432ba 56 TIGRFAM TIGR04129 CxxH_BA5709: CxxH/CxxC protein, BA_5709 family 2 55 2.4E-17 T 28-03-2018 IPR025626 YyzF-like protein CIG75_RS16315 7a444a6bdec61545c3ac10cfe82a1bb9 107 Pfam PF14034 Sporulation protein YtrH 6 104 9.4E-39 T 28-03-2018 IPR025689 Sporulation protein YtrH CIG75_RS15815 363968688e8a4d9dd870be047b6f0127 194 Gene3D G3DSA:3.40.30.10 34 183 3.3E-41 T 28-03-2018 CIG75_RS15815 363968688e8a4d9dd870be047b6f0127 194 SUPERFAMILY SSF52833 49 190 3.64E-45 T 28-03-2018 IPR012336 Thioredoxin-like fold CIG75_RS15815 363968688e8a4d9dd870be047b6f0127 194 Pfam PF00578 AhpC/TSA family 53 170 1.1E-29 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CIG75_RS15815 363968688e8a4d9dd870be047b6f0127 194 ProSitePatterns PS00194 Thioredoxin family active site. 81 99 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 CIG75_RS10295 e5921308cc1b0d76057bb6bbdaec3b48 330 SUPERFAMILY SSF56112 9 302 1.28E-50 T 28-03-2018 IPR011009 Protein kinase-like domain CIG75_RS10295 e5921308cc1b0d76057bb6bbdaec3b48 330 Gene3D G3DSA:3.30.200.20 1 98 4.1E-13 T 28-03-2018 CIG75_RS10295 e5921308cc1b0d76057bb6bbdaec3b48 330 Gene3D G3DSA:3.90.1200.10 99 318 1.2E-22 T 28-03-2018 CIG75_RS10295 e5921308cc1b0d76057bb6bbdaec3b48 330 Pfam PF01636 Phosphotransferase enzyme family 31 252 6.2E-19 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CIG75_RS13895 e3e176f5bb719cfd69afcc7b71c729c6 75 Pfam PF10031 Small integral membrane protein (DUF2273) 16 55 1.6E-9 T 28-03-2018 IPR018730 Protein of unknown function DUF2273 CIG75_RS09890 ae6dbb222c7392a0db05b0bb0101e03c 323 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 82 321 1.5E-67 T 28-03-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780 CIG75_RS09890 ae6dbb222c7392a0db05b0bb0101e03c 323 Pfam PF03099 Biotin/lipoate A/B protein ligase family 86 210 3.8E-16 T 28-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 CIG75_RS09890 ae6dbb222c7392a0db05b0bb0101e03c 323 Pfam PF08279 HTH domain 3 56 4.7E-18 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 CIG75_RS09890 ae6dbb222c7392a0db05b0bb0101e03c 323 SUPERFAMILY SSF55681 71 273 6.79E-61 T 28-03-2018 CIG75_RS09890 ae6dbb222c7392a0db05b0bb0101e03c 323 Pfam PF02237 Biotin protein ligase C terminal domain 277 321 8.4E-10 T 28-03-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780 CIG75_RS09890 ae6dbb222c7392a0db05b0bb0101e03c 323 Gene3D G3DSA:2.30.30.100 277 320 4.2E-10 T 28-03-2018 CIG75_RS09890 ae6dbb222c7392a0db05b0bb0101e03c 323 SUPERFAMILY SSF50037 282 322 8.24E-6 T 28-03-2018 IPR008988 Transcriptional repressor, C-terminal CIG75_RS09890 ae6dbb222c7392a0db05b0bb0101e03c 323 Gene3D G3DSA:3.30.930.10 57 276 1.2E-66 T 28-03-2018 CIG75_RS09890 ae6dbb222c7392a0db05b0bb0101e03c 323 Gene3D G3DSA:1.10.10.10 1 56 2.6E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS09890 ae6dbb222c7392a0db05b0bb0101e03c 323 SUPERFAMILY SSF46785 4 57 9.31E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS09890 ae6dbb222c7392a0db05b0bb0101e03c 323 Hamap MF_00978 Bifunctional ligase/repressor BirA [birA]. 4 323 38.175 T 28-03-2018 IPR030855 Bifunctional ligase/repressor BirA GO:0004077|GO:0006355 KEGG: 00780+6.3.4.15 CIG75_RS15530 4c7f678569b0bd63667005d13a9322a6 60 Gene3D G3DSA:1.10.720.10 2 50 5.7E-5 T 28-03-2018 CIG75_RS02940 796d79fb2e065a9413ee966d9f8d7915 412 Gene3D G3DSA:3.40.50.2020 1 220 8.3E-19 T 28-03-2018 CIG75_RS02940 796d79fb2e065a9413ee966d9f8d7915 412 SUPERFAMILY SSF53271 83 194 8.52E-7 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CIG75_RS02940 796d79fb2e065a9413ee966d9f8d7915 412 Pfam PF15609 Phosphoribosyl transferase 1 216 7.1E-70 T 28-03-2018 CIG75_RS02940 796d79fb2e065a9413ee966d9f8d7915 412 PIRSF PIRSF020967 267 406 7.4E-11 T 28-03-2018 IPR011214 Uncharacterised conserved protein UCP020967 CIG75_RS02940 796d79fb2e065a9413ee966d9f8d7915 412 PIRSF PIRSF020967 57 232 4.1E-23 T 28-03-2018 IPR011214 Uncharacterised conserved protein UCP020967 CIG75_RS02940 796d79fb2e065a9413ee966d9f8d7915 412 PIRSF PIRSF020967 1 48 3.5E-9 T 28-03-2018 IPR011214 Uncharacterised conserved protein UCP020967 CIG75_RS02940 796d79fb2e065a9413ee966d9f8d7915 412 Pfam PF12500 TRSP domain C terminus to PRTase_2 273 398 1.2E-39 T 28-03-2018 IPR022537 TRSP domain CIG75_RS14370 b3304d9b2bdfb2f1772f696257b684f9 366 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 8 354 7.1E-63 T 28-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 CIG75_RS14370 b3304d9b2bdfb2f1772f696257b684f9 366 Pfam PF03845 Spore germination protein 9 322 1.3E-61 T 28-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 CIG75_RS10415 73c373cd9e01438d3c0647b05d81a975 415 SUPERFAMILY SSF103473 9 399 4.45E-45 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS10415 73c373cd9e01438d3c0647b05d81a975 415 Pfam PF07690 Major Facilitator Superfamily 17 350 5.5E-32 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CIG75_RS10415 73c373cd9e01438d3c0647b05d81a975 415 Gene3D G3DSA:1.20.1250.20 209 408 2.4E-18 T 28-03-2018 CIG75_RS10415 73c373cd9e01438d3c0647b05d81a975 415 Gene3D G3DSA:1.20.1250.20 6 203 1.0E-24 T 28-03-2018 CIG75_RS18630 48ce72d2d20db9511683080f9e094552 174 Pfam PF05573 NosL 19 149 6.3E-21 T 28-03-2018 IPR008719 Nitrous oxide reductase accessory protein NosL CIG75_RS18630 48ce72d2d20db9511683080f9e094552 174 SUPERFAMILY SSF160387 52 159 2.28E-26 T 28-03-2018 CIG75_RS09995 7ac91d833f3ee35c7264803bb35f2fe6 283 SUPERFAMILY SSF55961 144 275 4.92E-20 T 28-03-2018 CIG75_RS09995 7ac91d833f3ee35c7264803bb35f2fe6 283 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 20 138 4.7E-9 T 28-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CIG75_RS09995 7ac91d833f3ee35c7264803bb35f2fe6 283 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 155 270 4.5E-16 T 28-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CIG75_RS09995 7ac91d833f3ee35c7264803bb35f2fe6 283 Gene3D G3DSA:3.30.530.20 5 141 1.2E-15 T 28-03-2018 IPR023393 START-like domain CIG75_RS09995 7ac91d833f3ee35c7264803bb35f2fe6 283 Gene3D G3DSA:3.30.530.20 142 280 6.0E-17 T 28-03-2018 IPR023393 START-like domain CIG75_RS09995 7ac91d833f3ee35c7264803bb35f2fe6 283 SUPERFAMILY SSF55961 9 143 1.16E-14 T 28-03-2018 CIG75_RS18720 d85c51b993a6bd300d4d62ebc9f37308 729 SMART SM00460 477 555 1.9E-19 T 28-03-2018 IPR002931 Transglutaminase-like CIG75_RS18720 d85c51b993a6bd300d4d62ebc9f37308 729 Gene3D G3DSA:3.90.260.10 420 580 2.5E-27 T 28-03-2018 IPR002931 Transglutaminase-like CIG75_RS18720 d85c51b993a6bd300d4d62ebc9f37308 729 Pfam PF01841 Transglutaminase-like superfamily 428 553 1.7E-29 T 28-03-2018 IPR002931 Transglutaminase-like CIG75_RS18720 d85c51b993a6bd300d4d62ebc9f37308 729 SUPERFAMILY SSF54001 411 563 6.17E-38 T 28-03-2018 CIG75_RS18720 d85c51b993a6bd300d4d62ebc9f37308 729 Pfam PF13559 Domain of unknown function (DUF4129) 651 715 2.8E-5 T 28-03-2018 IPR025403 Domain of unknown function DUF4129 CIG75_RS08895 2cca7eacf590090eca8e1c4f4f5ad17b 259 Pfam PF05690 Thiazole biosynthesis protein ThiG 6 253 3.9E-107 T 28-03-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 CIG75_RS08895 2cca7eacf590090eca8e1c4f4f5ad17b 259 Gene3D G3DSA:3.20.20.70 2 259 2.9E-54 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CIG75_RS08895 2cca7eacf590090eca8e1c4f4f5ad17b 259 SUPERFAMILY SSF110399 3 245 5.62E-80 T 28-03-2018 CIG75_RS08895 2cca7eacf590090eca8e1c4f4f5ad17b 259 Hamap MF_00443 Thiazole synthase [thiG]. 4 259 41.674 T 28-03-2018 IPR008867 Thiazole synthase GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 CIG75_RS10665 0b7cb67f68636abd6ad311c3adef6c2e 90 Gene3D G3DSA:3.90.1150.10 2 90 7.9E-5 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CIG75_RS05830 826484bf49a4392d794bc3e8e26a4e62 540 SUPERFAMILY SSF52540 6 256 6.31E-16 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS05830 826484bf49a4392d794bc3e8e26a4e62 540 SUPERFAMILY SSF75712 474 528 3.53E-5 T 28-03-2018 CIG75_RS05830 826484bf49a4392d794bc3e8e26a4e62 540 Gene3D G3DSA:3.40.50.300 4 285 3.4E-18 T 28-03-2018 CIG75_RS05830 826484bf49a4392d794bc3e8e26a4e62 540 Pfam PF13476 AAA domain 9 249 7.8E-14 T 28-03-2018 CIG75_RS10580 6b41d99e23c5c831f921d71a3e734ce4 424 Pfam PF05977 Transmembrane secretion effector 9 416 2.2E-33 T 28-03-2018 IPR010290 Transmembrane secretion effector CIG75_RS10580 6b41d99e23c5c831f921d71a3e734ce4 424 PRINTS PR01988 Putative bacilysin exporter bacE signature 14 36 7.2E-10 T 28-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CIG75_RS10580 6b41d99e23c5c831f921d71a3e734ce4 424 PRINTS PR01988 Putative bacilysin exporter bacE signature 171 188 7.2E-10 T 28-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CIG75_RS10580 6b41d99e23c5c831f921d71a3e734ce4 424 PRINTS PR01988 Putative bacilysin exporter bacE signature 262 279 7.2E-10 T 28-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CIG75_RS10580 6b41d99e23c5c831f921d71a3e734ce4 424 PRINTS PR01988 Putative bacilysin exporter bacE signature 78 96 7.2E-10 T 28-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CIG75_RS10580 6b41d99e23c5c831f921d71a3e734ce4 424 PRINTS PR01988 Putative bacilysin exporter bacE signature 144 165 7.2E-10 T 28-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CIG75_RS10580 6b41d99e23c5c831f921d71a3e734ce4 424 Gene3D G3DSA:1.20.1250.20 213 422 2.5E-15 T 28-03-2018 CIG75_RS10580 6b41d99e23c5c831f921d71a3e734ce4 424 Gene3D G3DSA:1.20.1250.20 1 208 3.0E-25 T 28-03-2018 CIG75_RS10580 6b41d99e23c5c831f921d71a3e734ce4 424 SUPERFAMILY SSF103473 10 403 9.02E-50 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS03620 eca53ec5b2a5274de824142a52a0fa92 445 Pfam PF10923 P-loop Domain of unknown function (DUF2791) 11 424 2.4E-147 T 28-03-2018 IPR021228 Protein of unknown function DUF2791 CIG75_RS03620 eca53ec5b2a5274de824142a52a0fa92 445 Gene3D G3DSA:3.40.50.300 27 263 8.1E-5 T 28-03-2018 CIG75_RS03620 eca53ec5b2a5274de824142a52a0fa92 445 SUPERFAMILY SSF52540 220 407 2.34E-6 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS03620 eca53ec5b2a5274de824142a52a0fa92 445 SUPERFAMILY SSF52540 35 118 2.34E-6 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS16095 d8ff4ecd7b4fdb04e4bcbd25e252c6a1 73 SUPERFAMILY SSF158379 9 63 2.75E-12 T 28-03-2018 IPR023164 YqgQ-like domain CIG75_RS16095 d8ff4ecd7b4fdb04e4bcbd25e252c6a1 73 Pfam PF06014 Bacterial protein of unknown function (DUF910) 9 62 4.6E-15 T 28-03-2018 IPR009256 Protein of unknown function DUF910 CIG75_RS16095 d8ff4ecd7b4fdb04e4bcbd25e252c6a1 73 Gene3D G3DSA:1.10.287.760 7 70 1.7E-16 T 28-03-2018 IPR023164 YqgQ-like domain CIG75_RS12720 068e1c14deb730e9fb6b2f6132c3e14a 223 Pfam PF10076 Uncharacterised protein conserved in bacteria (DUF2313) 10 120 5.8E-11 T 28-03-2018 IPR018755 Bacteriophage Mu-like, Gp48 CIG75_RS08030 284c9be3a1e8717c40c0436fd1a41ad9 345 SMART SM00382 123 248 5.9E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS08030 284c9be3a1e8717c40c0436fd1a41ad9 345 Gene3D G3DSA:3.40.50.300 274 344 6.2E-12 T 28-03-2018 CIG75_RS08030 284c9be3a1e8717c40c0436fd1a41ad9 345 Gene3D G3DSA:3.40.50.300 113 273 1.1E-30 T 28-03-2018 CIG75_RS08030 284c9be3a1e8717c40c0436fd1a41ad9 345 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 3 336 6.2E-135 T 28-03-2018 IPR006321 Pilus retraction protein PilT GO:0005524|GO:0006810 CIG75_RS08030 284c9be3a1e8717c40c0436fd1a41ad9 345 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 194 208 - T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CIG75_RS08030 284c9be3a1e8717c40c0436fd1a41ad9 345 Pfam PF00437 Type II/IV secretion system protein 78 270 1.4E-44 T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CIG75_RS08030 284c9be3a1e8717c40c0436fd1a41ad9 345 Gene3D G3DSA:3.30.450.90 1 101 1.1E-21 T 28-03-2018 CIG75_RS08030 284c9be3a1e8717c40c0436fd1a41ad9 345 SUPERFAMILY SSF52540 5 338 1.9E-66 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS03560 2349d149b4f7864790ec5e2cf7ad9f92 289 Gene3D G3DSA:3.40.50.720 2 288 9.2E-84 T 28-03-2018 CIG75_RS03560 2349d149b4f7864790ec5e2cf7ad9f92 289 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 194 213 7.0E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS03560 2349d149b4f7864790ec5e2cf7ad9f92 289 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 249 269 7.0E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS03560 2349d149b4f7864790ec5e2cf7ad9f92 289 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 232 7.0E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS03560 2349d149b4f7864790ec5e2cf7ad9f92 289 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 184 7.0E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS03560 2349d149b4f7864790ec5e2cf7ad9f92 289 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 133 7.0E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS03560 2349d149b4f7864790ec5e2cf7ad9f92 289 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 47 64 7.0E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS03560 2349d149b4f7864790ec5e2cf7ad9f92 289 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 174 182 1.7E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS03560 2349d149b4f7864790ec5e2cf7ad9f92 289 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 122 133 1.7E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS03560 2349d149b4f7864790ec5e2cf7ad9f92 289 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 194 213 1.7E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS03560 2349d149b4f7864790ec5e2cf7ad9f92 289 SUPERFAMILY SSF51735 44 286 8.53E-86 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS03560 2349d149b4f7864790ec5e2cf7ad9f92 289 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 181 209 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CIG75_RS03560 2349d149b4f7864790ec5e2cf7ad9f92 289 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 55 284 7.1E-65 T 28-03-2018 CIG75_RS17815 0e39ca811cdfefd990aa8c4f1f44a76d 370 Pfam PF01212 Beta-eliminating lyase 40 296 3.5E-35 T 28-03-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 CIG75_RS17815 0e39ca811cdfefd990aa8c4f1f44a76d 370 Gene3D G3DSA:3.40.640.10 3 243 1.8E-31 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CIG75_RS17815 0e39ca811cdfefd990aa8c4f1f44a76d 370 SUPERFAMILY SSF53383 28 323 1.11E-66 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CIG75_RS13955 d5f0458206fdb36cf802bf9f7a244fbe 328 SUPERFAMILY SSF52540 95 285 1.11E-13 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS13955 d5f0458206fdb36cf802bf9f7a244fbe 328 Gene3D G3DSA:3.40.50.300 72 297 1.6E-7 T 28-03-2018 CIG75_RS13955 d5f0458206fdb36cf802bf9f7a244fbe 328 TIGRFAM TIGR02858 spore_III_AA: stage III sporulation protein AA 33 315 1.8E-112 T 28-03-2018 IPR014217 Sporulation stage III, protein AA CIG75_RS13955 d5f0458206fdb36cf802bf9f7a244fbe 328 SMART SM00382 156 296 1.4E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS17130 de49622926300738b372bfbe0c6914fc 647 SUPERFAMILY SSF53649 253 564 5.4E-61 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CIG75_RS17130 de49622926300738b372bfbe0c6914fc 647 Gene3D G3DSA:3.40.720.10 248 555 1.4E-47 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CIG75_RS17130 de49622926300738b372bfbe0c6914fc 647 Pfam PF00884 Sulfatase 255 545 2.1E-41 T 28-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 CIG75_RS13960 00cc12cbeaedb5fcbcd4910bfb35eeef 151 Hamap MF_00489 UPF0178 protein YaiI [yaiI]. 1 144 24.538 T 28-03-2018 IPR003791 Protein of unknown function UPF0178 CIG75_RS13960 00cc12cbeaedb5fcbcd4910bfb35eeef 151 Pfam PF02639 Uncharacterized BCR, YaiI/YqxD family COG1671 22 142 6.8E-36 T 28-03-2018 IPR003791 Protein of unknown function UPF0178 CIG75_RS09930 ea058a5116ba478dab3602c90205eda8 207 Gene3D G3DSA:3.40.50.720 72 185 1.3E-16 T 28-03-2018 CIG75_RS09930 ea058a5116ba478dab3602c90205eda8 207 Hamap MF_01131 Redox-sensing transcriptional repressor Rex [rex]. 1 207 33.277 T 28-03-2018 IPR022876 Redox-sensing transcriptional repressor Rex GO:0005737|GO:0045892|GO:0051775 CIG75_RS09930 ea058a5116ba478dab3602c90205eda8 207 SUPERFAMILY SSF46785 8 79 1.16E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS09930 ea058a5116ba478dab3602c90205eda8 207 Pfam PF06971 Putative DNA-binding protein N-terminus 5 52 4.5E-20 T 28-03-2018 IPR009718 Rex DNA-binding, C-terminal domain GO:0005737|GO:0045892|GO:0051775 CIG75_RS09930 ea058a5116ba478dab3602c90205eda8 207 Pfam PF02629 CoA binding domain 83 179 1.2E-22 T 28-03-2018 IPR003781 CoA-binding GO:0048037 CIG75_RS09930 ea058a5116ba478dab3602c90205eda8 207 SUPERFAMILY SSF51735 82 205 2.3E-25 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS09930 ea058a5116ba478dab3602c90205eda8 207 SMART SM00881 79 180 4.6E-18 T 28-03-2018 IPR003781 CoA-binding GO:0048037 CIG75_RS09930 ea058a5116ba478dab3602c90205eda8 207 Gene3D G3DSA:1.10.10.10 4 71 2.0E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS03845 f1f9d296542d167e74694f4390971fee 195 SUPERFAMILY SSF101262 10 192 2.75E-15 T 28-03-2018 IPR007044 Cyclodeaminase/cyclohydrolase GO:0003824|GO:0044237 KEGG: 00340+2.1.2.5|KEGG: 00670+4.3.1.4+2.1.2.5|MetaCyc: PWY-5030|MetaCyc: PWY-5497|Reactome: R-HSA-70921 CIG75_RS03845 f1f9d296542d167e74694f4390971fee 195 Pfam PF04961 Formiminotransferase-cyclodeaminase 26 163 2.7E-12 T 28-03-2018 IPR007044 Cyclodeaminase/cyclohydrolase GO:0003824|GO:0044237 KEGG: 00340+2.1.2.5|KEGG: 00670+4.3.1.4+2.1.2.5|MetaCyc: PWY-5030|MetaCyc: PWY-5497|Reactome: R-HSA-70921 CIG75_RS16735 6d46c857c8d7cd75dd26233c148f653a 250 Gene3D G3DSA:3.30.70.1100 141 246 6.2E-30 T 28-03-2018 CIG75_RS16735 6d46c857c8d7cd75dd26233c148f653a 250 Hamap MF_01442 Putative heme-dependent peroxidase . 3 250 52.947 T 28-03-2018 IPR031332 Putative heme-dependent peroxidase, UPF0447 family CIG75_RS16735 6d46c857c8d7cd75dd26233c148f653a 250 SUPERFAMILY SSF54909 4 249 2.25E-90 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CIG75_RS16735 6d46c857c8d7cd75dd26233c148f653a 250 Gene3D G3DSA:3.30.70.1030 6 138 1.3E-40 T 28-03-2018 CIG75_RS16735 6d46c857c8d7cd75dd26233c148f653a 250 Pfam PF06778 Chlorite dismutase 35 238 9.6E-75 T 28-03-2018 IPR010644 Putative heme-dependent peroxidase/Chlorite dismutase CIG75_RS17600 2a15c27e24b5ed5978ec8c25f7ecd301 320 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 163 317 8.7E-60 T 28-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 CIG75_RS17600 2a15c27e24b5ed5978ec8c25f7ecd301 320 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 272 281 5.5E-29 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CIG75_RS17600 2a15c27e24b5ed5978ec8c25f7ecd301 320 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 284 307 5.5E-29 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CIG75_RS17600 2a15c27e24b5ed5978ec8c25f7ecd301 320 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 144 155 5.5E-29 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CIG75_RS17600 2a15c27e24b5ed5978ec8c25f7ecd301 320 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 62 81 5.5E-29 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CIG75_RS17600 2a15c27e24b5ed5978ec8c25f7ecd301 320 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 17 319 3.1E-133 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CIG75_RS17600 2a15c27e24b5ed5978ec8c25f7ecd301 320 PRINTS PR00102 Ornithine carbamoyltransferase signature 93 106 1.3E-31 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CIG75_RS17600 2a15c27e24b5ed5978ec8c25f7ecd301 320 PRINTS PR00102 Ornithine carbamoyltransferase signature 133 147 1.3E-31 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CIG75_RS17600 2a15c27e24b5ed5978ec8c25f7ecd301 320 PRINTS PR00102 Ornithine carbamoyltransferase signature 236 246 1.3E-31 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CIG75_RS17600 2a15c27e24b5ed5978ec8c25f7ecd301 320 PRINTS PR00102 Ornithine carbamoyltransferase signature 60 74 1.3E-31 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CIG75_RS17600 2a15c27e24b5ed5978ec8c25f7ecd301 320 PRINTS PR00102 Ornithine carbamoyltransferase signature 298 309 1.3E-31 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CIG75_RS17600 2a15c27e24b5ed5978ec8c25f7ecd301 320 Gene3D G3DSA:3.40.50.1370 157 320 5.0E-61 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CIG75_RS17600 2a15c27e24b5ed5978ec8c25f7ecd301 320 SUPERFAMILY SSF53671 12 319 3.14E-110 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CIG75_RS17600 2a15c27e24b5ed5978ec8c25f7ecd301 320 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 62 69 - T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CIG75_RS17600 2a15c27e24b5ed5978ec8c25f7ecd301 320 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 17 157 5.4E-52 T 28-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 CIG75_RS17600 2a15c27e24b5ed5978ec8c25f7ecd301 320 Gene3D G3DSA:3.40.50.1370 10 156 5.7E-59 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CIG75_RS17600 2a15c27e24b5ed5978ec8c25f7ecd301 320 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 16 320 83.799 T 28-03-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 CIG75_RS07210 8236a9691b4c5db7e30c8996d92e65a5 282 SUPERFAMILY SSF51730 11 278 2.79E-74 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like CIG75_RS07210 8236a9691b4c5db7e30c8996d92e65a5 282 Pfam PF01619 Proline dehydrogenase 20 272 2.8E-37 T 28-03-2018 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|Reactome: R-HSA-70688 CIG75_RS07210 8236a9691b4c5db7e30c8996d92e65a5 282 PIRSF PIRSF000196 1 282 1.3E-118 T 28-03-2018 IPR008219 Proline dehydrogenase, bacteria and archaea GO:0004657|GO:0010133 KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922 CIG75_RS07210 8236a9691b4c5db7e30c8996d92e65a5 282 Gene3D G3DSA:3.20.20.220 1 281 1.3E-72 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like CIG75_RS08370 8ae8e98f90791a2b1bc30e86cbaf9c29 288 Pfam PF11382 Copper transport outer membrane protein, MctB 2 277 5.6E-29 T 28-03-2018 IPR021522 Copper transporter MctB GO:0006810 CIG75_RS05690 b29d8a162c464b04778ee6c711bd9806 144 SUPERFAMILY SSF54631 1 118 6.32E-35 T 28-03-2018 CIG75_RS05690 b29d8a162c464b04778ee6c711bd9806 144 Pfam PF00571 CBS domain 3 54 1.7E-9 T 28-03-2018 IPR000644 CBS domain CIG75_RS05690 b29d8a162c464b04778ee6c711bd9806 144 Pfam PF00571 CBS domain 69 119 1.9E-13 T 28-03-2018 IPR000644 CBS domain CIG75_RS05690 b29d8a162c464b04778ee6c711bd9806 144 Gene3D G3DSA:3.10.580.10 1 141 4.2E-28 T 28-03-2018 CIG75_RS05690 b29d8a162c464b04778ee6c711bd9806 144 SMART SM00116 76 123 4.4E-11 T 28-03-2018 IPR000644 CBS domain CIG75_RS05690 b29d8a162c464b04778ee6c711bd9806 144 SMART SM00116 10 58 2.5E-4 T 28-03-2018 IPR000644 CBS domain CIG75_RS15135 1ec300815b71f2a0ae1858d7ce60e328 408 SUPERFAMILY SSF103473 9 401 1.83E-41 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS15135 1ec300815b71f2a0ae1858d7ce60e328 408 Pfam PF05977 Transmembrane secretion effector 18 396 3.4E-18 T 28-03-2018 IPR010290 Transmembrane secretion effector CIG75_RS15135 1ec300815b71f2a0ae1858d7ce60e328 408 Gene3D G3DSA:1.20.1250.20 218 406 1.9E-15 T 28-03-2018 CIG75_RS15135 1ec300815b71f2a0ae1858d7ce60e328 408 Gene3D G3DSA:1.20.1250.20 5 207 4.3E-22 T 28-03-2018 CIG75_RS12570 e47f7d986138e828c9f8c395df808e38 341 SMART SM00382 49 233 7.6E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS12570 e47f7d986138e828c9f8c395df808e38 341 Pfam PF00005 ABC transporter 41 184 2.8E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS12570 e47f7d986138e828c9f8c395df808e38 341 SUPERFAMILY SSF52540 35 254 2.77E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS12570 e47f7d986138e828c9f8c395df808e38 341 Gene3D G3DSA:3.40.50.300 1 262 1.3E-50 T 28-03-2018 CIG75_RS12570 e47f7d986138e828c9f8c395df808e38 341 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS13060 15d41cc93b8ad5253537e06115632188 158 ProSitePatterns PS00855 Signal peptidases II signature. 92 104 - T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CIG75_RS13060 15d41cc93b8ad5253537e06115632188 158 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 44 52 9.7E-17 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CIG75_RS13060 15d41cc93b8ad5253537e06115632188 158 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 123 139 9.7E-17 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CIG75_RS13060 15d41cc93b8ad5253537e06115632188 158 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 89 104 9.7E-17 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CIG75_RS13060 15d41cc93b8ad5253537e06115632188 158 TIGRFAM TIGR00077 lspA: signal peptidase II 2 145 6.4E-39 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CIG75_RS13060 15d41cc93b8ad5253537e06115632188 158 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 2 148 15.089 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CIG75_RS13060 15d41cc93b8ad5253537e06115632188 158 Pfam PF01252 Signal peptidase (SPase) II 6 142 2.5E-37 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CIG75_RS05315 2e13bc9e43e186b8d18c600b58039f61 143 SUPERFAMILY SSF53098 1 141 7.97E-56 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CIG75_RS05315 2e13bc9e43e186b8d18c600b58039f61 143 Gene3D G3DSA:3.30.420.10 1 143 2.5E-50 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CIG75_RS05315 2e13bc9e43e186b8d18c600b58039f61 143 Hamap MF_00042 Ribonuclease H [rnhA]. 1 143 27.478 T 28-03-2018 IPR022892 Ribonuclease HI GO:0004523 CIG75_RS05315 2e13bc9e43e186b8d18c600b58039f61 143 Pfam PF00075 RNase H 2 140 2.1E-43 T 28-03-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 CIG75_RS15775 d432abd80736edd50bb3d5950d5b33a2 226 Pfam PF12710 haloacid dehalogenase-like hydrolase 7 178 1.8E-17 T 28-03-2018 CIG75_RS15775 d432abd80736edd50bb3d5950d5b33a2 226 Hamap MF_01680 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase [mtnX]. 3 217 41.993 T 28-03-2018 IPR017718 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase GO:0016791|GO:0071267 KEGG: 00270+3.1.3.87|MetaCyc: PWY-4361 CIG75_RS15775 d432abd80736edd50bb3d5950d5b33a2 226 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 6 179 1.4E-25 T 28-03-2018 CIG75_RS15775 d432abd80736edd50bb3d5950d5b33a2 226 Gene3D G3DSA:3.40.50.1000 1 224 7.5E-16 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS15775 d432abd80736edd50bb3d5950d5b33a2 226 TIGRFAM TIGR01489 DKMTPPase-SF: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase 6 187 1.9E-40 T 28-03-2018 IPR006384 Pyridoxal phosphate phosphatase-related GO:0016791 CIG75_RS15775 d432abd80736edd50bb3d5950d5b33a2 226 SUPERFAMILY SSF56784 1 218 1.47E-46 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS03450 bd51286e67c6105330bcfa87fea8d492 167 SUPERFAMILY SSF160207 30 166 9.15E-5 T 28-03-2018 CIG75_RS03450 bd51286e67c6105330bcfa87fea8d492 167 Gene3D G3DSA:3.40.1590.10 24 166 1.9E-10 T 28-03-2018 CIG75_RS03045 f1cd3d78707e395a60e7133f88b9b6a1 112 Pfam PF00893 Small Multidrug Resistance protein 4 92 7.0E-22 T 28-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 CIG75_RS03045 f1cd3d78707e395a60e7133f88b9b6a1 112 SUPERFAMILY SSF103481 8 100 3.27E-14 T 28-03-2018 CIG75_RS14615 338a44cad08a0bbedbb1270bc8bd9258 214 TIGRFAM TIGR01065 hlyIII: channel protein, hemolysin III family 8 211 2.7E-56 T 28-03-2018 IPR005744 Hly-III GO:0016021|GO:0019835 CIG75_RS14615 338a44cad08a0bbedbb1270bc8bd9258 214 Pfam PF03006 Haemolysin-III related 7 205 1.4E-44 T 28-03-2018 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 CIG75_RS07890 f6169b1f3f21ce777b0460df1145ab4a 272 Pfam PF01578 Cytochrome C assembly protein 68 264 7.0E-32 T 28-03-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 CIG75_RS17265 0f93d12f449a1260e486726f5824e6a3 196 Pfam PF12840 Helix-turn-helix domain 15 70 7.8E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS17265 0f93d12f449a1260e486726f5824e6a3 196 SMART SM00418 13 93 0.0023 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CIG75_RS17265 0f93d12f449a1260e486726f5824e6a3 196 SUPERFAMILY SSF46785 11 119 9.31E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS17265 0f93d12f449a1260e486726f5824e6a3 196 Gene3D G3DSA:1.10.10.10 2 182 4.7E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS15900 63146fce6025eabd7c91b0b81658cb64 161 Pfam PF13185 GAF domain 50 152 3.4E-11 T 28-03-2018 IPR003018 GAF domain GO:0005515 CIG75_RS15900 63146fce6025eabd7c91b0b81658cb64 161 Gene3D G3DSA:3.30.450.40 9 156 1.7E-27 T 28-03-2018 IPR029016 GAF domain-like CIG75_RS15900 63146fce6025eabd7c91b0b81658cb64 161 SMART SM00065 31 160 0.0022 T 28-03-2018 IPR003018 GAF domain GO:0005515 CIG75_RS15900 63146fce6025eabd7c91b0b81658cb64 161 SUPERFAMILY SSF55781 14 155 2.29E-45 T 28-03-2018 IPR029016 GAF domain-like CIG75_RS15900 63146fce6025eabd7c91b0b81658cb64 161 ProSitePatterns PS01320 Uncharacterized protein family UPF0067 signature. 98 115 - T 28-03-2018 IPR000614 Free Met sulfoxide reductase conserved site CIG75_RS06730 584cabd22ef7c87f3010c169ea93ef11 352 TIGRFAM TIGR01681 HAD-SF-IIIC: HAD phosphatase, family IIIC 17 124 4.0E-19 T 28-03-2018 IPR010033 HAD-superfamily phosphatase, subfamily IIIC CIG75_RS06730 584cabd22ef7c87f3010c169ea93ef11 352 Gene3D G3DSA:3.40.50.1000 1 163 9.1E-15 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS06730 584cabd22ef7c87f3010c169ea93ef11 352 SUPERFAMILY SSF56784 14 119 2.52E-15 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS06730 584cabd22ef7c87f3010c169ea93ef11 352 TIGRFAM TIGR01686 FkbH: FkbH domain 15 322 4.4E-83 T 28-03-2018 IPR010037 FkbH domain CIG75_RS06730 584cabd22ef7c87f3010c169ea93ef11 352 SUPERFAMILY SSF55729 188 326 5.7E-8 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CIG75_RS06730 584cabd22ef7c87f3010c169ea93ef11 352 Gene3D G3DSA:3.40.630.30 186 330 6.7E-8 T 28-03-2018 CIG75_RS03795 1d18a11323f0a48f000fb7dc0efa0b30 103 Gene3D G3DSA:3.30.70.1060 2 96 1.3E-15 T 28-03-2018 CIG75_RS03795 1d18a11323f0a48f000fb7dc0efa0b30 103 Pfam PF03795 YCII-related domain 11 92 3.3E-10 T 28-03-2018 IPR005545 YCII-related CIG75_RS03795 1d18a11323f0a48f000fb7dc0efa0b30 103 SUPERFAMILY SSF54909 22 94 1.07E-13 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CIG75_RS14510 fed2ff8bbc0ee0cc7cc5437f3185a05b 835 Pfam PF01136 Peptidase family U32 614 815 2.0E-20 T 28-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 CIG75_RS14510 fed2ff8bbc0ee0cc7cc5437f3185a05b 835 Pfam PF01136 Peptidase family U32 81 306 2.1E-84 T 28-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 CIG75_RS14510 fed2ff8bbc0ee0cc7cc5437f3185a05b 835 Pfam PF12392 Collagenase 402 522 2.6E-24 T 28-03-2018 IPR020988 Peptidase U32, collagenase CIG75_RS14510 fed2ff8bbc0ee0cc7cc5437f3185a05b 835 Gene3D G3DSA:3.20.20.70 59 754 8.4E-14 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CIG75_RS15215 ebe3fe49d5cfbc7c0ac8ace4c4ba44dd 123 ProSitePatterns PS00893 Nudix box signature. 14 35 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CIG75_RS15215 ebe3fe49d5cfbc7c0ac8ace4c4ba44dd 123 Gene3D G3DSA:3.90.79.10 1 118 1.8E-16 T 28-03-2018 CIG75_RS15215 ebe3fe49d5cfbc7c0ac8ace4c4ba44dd 123 PRINTS PR00502 NUDIX hydrolase family signature 23 38 1.8E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CIG75_RS15215 ebe3fe49d5cfbc7c0ac8ace4c4ba44dd 123 PRINTS PR00502 NUDIX hydrolase family signature 9 23 1.8E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CIG75_RS15215 ebe3fe49d5cfbc7c0ac8ace4c4ba44dd 123 SUPERFAMILY SSF55811 7 85 1.49E-17 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CIG75_RS15215 ebe3fe49d5cfbc7c0ac8ace4c4ba44dd 123 Pfam PF00293 NUDIX domain 5 82 9.7E-11 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CIG75_RS10985 61c2dda9cd625eb50a176a2678590711 523 SUPERFAMILY SSF55469 100 251 2.22E-9 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CIG75_RS10985 61c2dda9cd625eb50a176a2678590711 523 TIGRFAM TIGR03605 antibiot_sagB: SagB-type dehydrogenase domain 81 236 1.2E-23 T 28-03-2018 IPR020051 SagB-type dehydrogenase domain CIG75_RS10985 61c2dda9cd625eb50a176a2678590711 523 Pfam PF00881 Nitroreductase family 77 234 1.7E-7 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CIG75_RS10985 61c2dda9cd625eb50a176a2678590711 523 Gene3D G3DSA:3.40.109.10 68 240 2.9E-18 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CIG75_RS10985 61c2dda9cd625eb50a176a2678590711 523 Gene3D G3DSA:3.40.109.10 265 511 4.1E-16 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CIG75_RS10985 61c2dda9cd625eb50a176a2678590711 523 SUPERFAMILY SSF55469 429 510 1.13E-7 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CIG75_RS03235 367e928b2f38460874c725fff72481b0 194 Pfam PF09335 SNARE associated Golgi protein 35 152 1.5E-22 T 28-03-2018 IPR032816 SNARE associated Golgi protein CIG75_RS01540 4de56a9f8b76d8ca3bc54b56803ab0e7 447 TIGRFAM TIGR03820 lys_2_3_AblA: lysine-2,3-aminomutase 29 427 7.2E-192 T 28-03-2018 IPR022459 Lysine-2,3-aminomutase KEGG: 00310+5.4.3.2 CIG75_RS01540 4de56a9f8b76d8ca3bc54b56803ab0e7 447 PIRSF PIRSF004911 7 410 7.7E-166 T 28-03-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase CIG75_RS01540 4de56a9f8b76d8ca3bc54b56803ab0e7 447 TIGRFAM TIGR00238 TIGR00238: KamA family protein 23 350 3.9E-130 T 28-03-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase CIG75_RS01540 4de56a9f8b76d8ca3bc54b56803ab0e7 447 Gene3D G3DSA:3.20.20.70 125 335 4.5E-24 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CIG75_RS01540 4de56a9f8b76d8ca3bc54b56803ab0e7 447 Pfam PF12544 Lysine-2,3-aminomutase 329 437 5.4E-41 T 28-03-2018 IPR025895 Lysine-2,3-aminomutase, C-terminal domain CIG75_RS01540 4de56a9f8b76d8ca3bc54b56803ab0e7 447 Pfam PF04055 Radical SAM superfamily 138 285 5.9E-10 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CIG75_RS01540 4de56a9f8b76d8ca3bc54b56803ab0e7 447 SUPERFAMILY SSF102114 122 363 3.92E-36 T 28-03-2018 CIG75_RS01540 4de56a9f8b76d8ca3bc54b56803ab0e7 447 Pfam PF13353 4Fe-4S single cluster domain 135 207 9.8E-6 T 28-03-2018 CIG75_RS16495 d20a01f6602eb7ee1779ad57559dfe42 380 Pfam PF00999 Sodium/hydrogen exchanger family 9 369 2.0E-76 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CIG75_RS16495 d20a01f6602eb7ee1779ad57559dfe42 380 Gene3D G3DSA:1.20.91.10 222 309 1.6E-16 T 28-03-2018 CIG75_RS03400 7b5f74d445df57fea5a9030115b833e0 155 Gene3D G3DSA:2.60.40.420 36 155 4.8E-27 T 28-03-2018 IPR008972 Cupredoxin CIG75_RS03400 7b5f74d445df57fea5a9030115b833e0 155 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 100 148 - T 28-03-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CIG75_RS03400 7b5f74d445df57fea5a9030115b833e0 155 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 82 149 1.5E-13 T 28-03-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CIG75_RS03400 7b5f74d445df57fea5a9030115b833e0 155 PRINTS PR01166 Cytochrome c oxidase subunit II signature 2 14 4.2E-6 T 28-03-2018 CIG75_RS03400 7b5f74d445df57fea5a9030115b833e0 155 PRINTS PR01166 Cytochrome c oxidase subunit II signature 137 154 4.2E-6 T 28-03-2018 CIG75_RS03400 7b5f74d445df57fea5a9030115b833e0 155 PRINTS PR01166 Cytochrome c oxidase subunit II signature 99 119 4.2E-6 T 28-03-2018 CIG75_RS03400 7b5f74d445df57fea5a9030115b833e0 155 Gene3D G3DSA:1.20.1070.10 3 33 3.6E-13 T 28-03-2018 CIG75_RS03400 7b5f74d445df57fea5a9030115b833e0 155 SUPERFAMILY SSF49503 59 154 1.74E-30 T 28-03-2018 IPR008972 Cupredoxin CIG75_RS08240 0824d9efb0c1c04119959f1cbc368624 308 SUPERFAMILY SSF55729 40 119 7.37E-5 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CIG75_RS08240 0824d9efb0c1c04119959f1cbc368624 308 Gene3D G3DSA:3.40.630.30 16 177 1.5E-6 T 28-03-2018 CIG75_RS06010 e02687e20031c9de0983c4e665134548 134 Pfam PF10710 Protein of unknown function (DUF2512) 19 131 8.0E-10 T 28-03-2018 IPR019649 Protein of unknown function DUF2512 CIG75_RS01915 a6176aef666f387e8279dc76ba56ab1b 255 Hamap MF_01393 ATP synthase subunit a [atpB]. 1 252 13.106 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CIG75_RS01915 a6176aef666f387e8279dc76ba56ab1b 255 SUPERFAMILY SSF81336 71 246 6.02E-32 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CIG75_RS01915 a6176aef666f387e8279dc76ba56ab1b 255 PRINTS PR00123 ATP synthase A subunit signature 232 247 8.8E-7 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CIG75_RS01915 a6176aef666f387e8279dc76ba56ab1b 255 PRINTS PR00123 ATP synthase A subunit signature 78 94 8.8E-7 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CIG75_RS01915 a6176aef666f387e8279dc76ba56ab1b 255 ProSitePatterns PS00449 ATP synthase a subunit signature. 183 192 - T 28-03-2018 IPR023011 ATP synthase, F0 complex, subunit A, active site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CIG75_RS01915 a6176aef666f387e8279dc76ba56ab1b 255 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 16 248 1.3E-40 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CIG75_RS01915 a6176aef666f387e8279dc76ba56ab1b 255 Gene3D G3DSA:1.20.120.220 69 252 1.2E-37 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CIG75_RS01915 a6176aef666f387e8279dc76ba56ab1b 255 Pfam PF00119 ATP synthase A chain 22 246 1.7E-50 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CIG75_RS04520 26b0f8f3d4d75ff694a47fcdbbb98f36 175 Gene3D G3DSA:3.40.630.30 2 174 1.1E-24 T 28-03-2018 CIG75_RS04520 26b0f8f3d4d75ff694a47fcdbbb98f36 175 Pfam PF13302 Acetyltransferase (GNAT) domain 12 146 2.4E-24 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CIG75_RS04520 26b0f8f3d4d75ff694a47fcdbbb98f36 175 SUPERFAMILY SSF55729 4 170 2.85E-43 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CIG75_RS16025 0433880911baefbf7a5fce3427b49226 200 Gene3D G3DSA:3.10.350.10 17 71 7.7E-20 T 28-03-2018 CIG75_RS16025 0433880911baefbf7a5fce3427b49226 200 Gene3D G3DSA:3.40.33.10 72 200 5.1E-19 T 28-03-2018 IPR014044 CAP domain CIG75_RS16025 0433880911baefbf7a5fce3427b49226 200 Pfam PF01476 LysM domain 24 67 3.3E-19 T 28-03-2018 IPR018392 LysM domain CIG75_RS16025 0433880911baefbf7a5fce3427b49226 200 SMART SM00257 23 67 3.3E-18 T 28-03-2018 IPR018392 LysM domain CIG75_RS16025 0433880911baefbf7a5fce3427b49226 200 Pfam PF00188 Cysteine-rich secretory protein family 82 197 6.6E-20 T 28-03-2018 IPR014044 CAP domain CIG75_RS16025 0433880911baefbf7a5fce3427b49226 200 TIGRFAM TIGR02909 spore_YkwD: uncharacterized protein, YkwD family 74 199 8.9E-58 T 28-03-2018 IPR014258 CAP domain, YkwD-like CIG75_RS16025 0433880911baefbf7a5fce3427b49226 200 SUPERFAMILY SSF55797 75 197 7.59E-29 T 28-03-2018 IPR014044 CAP domain CIG75_RS16025 0433880911baefbf7a5fce3427b49226 200 SUPERFAMILY SSF54106 22 67 1.57E-13 T 28-03-2018 IPR018392 LysM domain CIG75_RS16635 7b7562141f9cffd943c6f3a2351c8ce8 262 Pfam PF02421 Ferrous iron transport protein B 28 180 3.9E-59 T 28-03-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 CIG75_RS16635 7b7562141f9cffd943c6f3a2351c8ce8 262 Gene3D G3DSA:3.40.50.300 24 211 4.4E-31 T 28-03-2018 CIG75_RS16635 7b7562141f9cffd943c6f3a2351c8ce8 262 SUPERFAMILY SSF52540 28 203 1.78E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS16635 7b7562141f9cffd943c6f3a2351c8ce8 262 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 29 49 2.7E-6 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CIG75_RS16635 7b7562141f9cffd943c6f3a2351c8ce8 262 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 77 92 2.7E-6 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CIG75_RS19800 8e1406d6eaa15ed214d5569f5f9a7041 177 SUPERFAMILY SSF82679 2 113 2.49E-42 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CIG75_RS19800 8e1406d6eaa15ed214d5569f5f9a7041 177 SMART SM00738 2 113 5.3E-55 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CIG75_RS19800 8e1406d6eaa15ed214d5569f5f9a7041 177 SUPERFAMILY SSF50104 121 177 2.31E-17 T 28-03-2018 IPR008991 Translation protein SH3-like domain CIG75_RS19800 8e1406d6eaa15ed214d5569f5f9a7041 177 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 2 177 28.003 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CIG75_RS19800 8e1406d6eaa15ed214d5569f5f9a7041 177 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 5 177 5.9E-68 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CIG75_RS19800 8e1406d6eaa15ed214d5569f5f9a7041 177 Gene3D G3DSA:3.30.70.940 2 116 2.3E-45 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CIG75_RS19800 8e1406d6eaa15ed214d5569f5f9a7041 177 PRINTS PR00338 Transcription termination factor NUSG signature 135 150 1.2E-20 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CIG75_RS19800 8e1406d6eaa15ed214d5569f5f9a7041 177 PRINTS PR00338 Transcription termination factor NUSG signature 153 169 1.2E-20 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CIG75_RS19800 8e1406d6eaa15ed214d5569f5f9a7041 177 PRINTS PR00338 Transcription termination factor NUSG signature 57 69 1.2E-20 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CIG75_RS19800 8e1406d6eaa15ed214d5569f5f9a7041 177 Pfam PF02357 Transcription termination factor nusG 3 110 6.8E-30 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CIG75_RS19800 8e1406d6eaa15ed214d5569f5f9a7041 177 Gene3D G3DSA:2.30.30.30 118 177 1.3E-18 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 CIG75_RS12740 e9af9556ed17f91b13e9149a3dd7e8ba 357 SUPERFAMILY SSF69279 17 190 7.23E-9 T 28-03-2018 CIG75_RS12740 e9af9556ed17f91b13e9149a3dd7e8ba 357 Gene3D G3DSA:2.30.300.10 14 156 0.0037 T 28-03-2018 CIG75_RS00775 224bbd33d7db6f8b8c5eee4d1449c8f1 461 PIRSF PIRSF016636 1 461 1.6E-145 T 28-03-2018 IPR024194 Alginate O-acetyltransferase AlgI/D-alanyl transfer protein DltB CIG75_RS00775 224bbd33d7db6f8b8c5eee4d1449c8f1 461 PIRSF PIRSF500217 1 461 1.3E-148 T 28-03-2018 IPR028362 Alginate O-acetyltransferase AlgI GO:0042121 CIG75_RS00775 224bbd33d7db6f8b8c5eee4d1449c8f1 461 Pfam PF03062 MBOAT, membrane-bound O-acyltransferase family 147 344 3.7E-28 T 28-03-2018 IPR004299 Membrane bound O-acyl transferase, MBOAT CIG75_RS00535 b641c5bffa4194c092c1803d80ec2962 230 SUPERFAMILY SSF46894 129 228 1.24E-32 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CIG75_RS00535 b641c5bffa4194c092c1803d80ec2962 230 SUPERFAMILY SSF52172 2 123 2.42E-43 T 28-03-2018 IPR011006 CheY-like superfamily CIG75_RS00535 b641c5bffa4194c092c1803d80ec2962 230 SMART SM00448 3 113 3.3E-46 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CIG75_RS00535 b641c5bffa4194c092c1803d80ec2962 230 SMART SM00862 152 228 5.4E-28 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CIG75_RS00535 b641c5bffa4194c092c1803d80ec2962 230 Pfam PF00486 Transcriptional regulatory protein, C terminal 153 228 3.5E-28 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CIG75_RS00535 b641c5bffa4194c092c1803d80ec2962 230 Gene3D G3DSA:3.40.50.2300 1 125 1.3E-38 T 28-03-2018 CIG75_RS00535 b641c5bffa4194c092c1803d80ec2962 230 Gene3D G3DSA:1.10.10.10 126 230 4.7E-34 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS00535 b641c5bffa4194c092c1803d80ec2962 230 Pfam PF00072 Response regulator receiver domain 5 114 8.6E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CIG75_RS18805 9669c9f6d217c74589922a77092016c3 650 Gene3D G3DSA:3.40.50.300 2 297 2.8E-53 T 28-03-2018 CIG75_RS18805 9669c9f6d217c74589922a77092016c3 650 SUPERFAMILY SSF52540 7 249 5.5E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS18805 9669c9f6d217c74589922a77092016c3 650 SUPERFAMILY SSF52540 312 535 1.69E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS18805 9669c9f6d217c74589922a77092016c3 650 Gene3D G3DSA:1.20.58.410 577 650 2.3E-5 T 28-03-2018 CIG75_RS18805 9669c9f6d217c74589922a77092016c3 650 Gene3D G3DSA:3.40.50.300 298 558 4.5E-56 T 28-03-2018 CIG75_RS18805 9669c9f6d217c74589922a77092016c3 650 Pfam PF12848 ABC transporter 234 320 2.2E-26 T 28-03-2018 IPR032781 ABC-transporter extension domain CIG75_RS18805 9669c9f6d217c74589922a77092016c3 650 Pfam PF16326 ABC transporter C-terminal domain 581 645 3.4E-12 T 28-03-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 CIG75_RS18805 9669c9f6d217c74589922a77092016c3 650 ProSitePatterns PS00211 ABC transporters family signature. 448 462 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS18805 9669c9f6d217c74589922a77092016c3 650 SMART SM00382 355 520 1.4E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS18805 9669c9f6d217c74589922a77092016c3 650 SMART SM00382 28 310 9.2E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS18805 9669c9f6d217c74589922a77092016c3 650 ProSitePatterns PS00211 ABC transporters family signature. 167 181 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS18805 9669c9f6d217c74589922a77092016c3 650 Pfam PF00005 ABC transporter 19 195 1.2E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS18805 9669c9f6d217c74589922a77092016c3 650 Pfam PF00005 ABC transporter 347 476 1.3E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS02395 6f01e5fa5e35fc065cd3e6df30b80953 292 SUPERFAMILY SSF46785 41 98 7.39E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS02395 6f01e5fa5e35fc065cd3e6df30b80953 292 Pfam PF03444 Winged helix-turn-helix transcription repressor, HrcA DNA-binding 27 89 2.9E-8 T 28-03-2018 IPR005104 Winged helix-turn-helix transcription repressor, HrcA DNA-binding domain GO:0003677|GO:0006355 CIG75_RS02395 6f01e5fa5e35fc065cd3e6df30b80953 292 Gene3D G3DSA:1.10.10.10 19 271 3.8E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS05575 db1e044b191668e6f84a62cb854309f9 307 SUPERFAMILY SSF103481 191 292 7.06E-16 T 28-03-2018 CIG75_RS05575 db1e044b191668e6f84a62cb854309f9 307 SUPERFAMILY SSF103481 42 146 2.62E-12 T 28-03-2018 CIG75_RS05575 db1e044b191668e6f84a62cb854309f9 307 Pfam PF00892 EamA-like transporter family 154 289 1.7E-20 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CIG75_RS05575 db1e044b191668e6f84a62cb854309f9 307 Pfam PF00892 EamA-like transporter family 11 142 2.8E-14 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CIG75_RS15235 4947450751b71d12afeebae98c8dc7e9 158 SUPERFAMILY SSF55729 1 158 8.1E-35 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CIG75_RS15235 4947450751b71d12afeebae98c8dc7e9 158 Pfam PF00583 Acetyltransferase (GNAT) family 40 132 3.5E-18 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CIG75_RS15235 4947450751b71d12afeebae98c8dc7e9 158 Gene3D G3DSA:3.40.630.30 1 158 8.2E-36 T 28-03-2018 CIG75_RS10960 32e68a262c4ed66b8d8edc3fc9e19f73 245 PRINTS PR00164 ABC-2 type transport system membrane protein signature 132 156 7.4E-13 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CIG75_RS10960 32e68a262c4ed66b8d8edc3fc9e19f73 245 PRINTS PR00164 ABC-2 type transport system membrane protein signature 169 188 7.4E-13 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CIG75_RS10960 32e68a262c4ed66b8d8edc3fc9e19f73 245 PRINTS PR00164 ABC-2 type transport system membrane protein signature 189 208 7.4E-13 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CIG75_RS10960 32e68a262c4ed66b8d8edc3fc9e19f73 245 Pfam PF01061 ABC-2 type transporter 7 206 3.0E-31 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CIG75_RS10960 32e68a262c4ed66b8d8edc3fc9e19f73 245 PIRSF PIRSF006648 1 244 1.3E-31 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CIG75_RS01585 f90f34c166a5b7389d757938fdb8aad3 356 SUPERFAMILY SSF161098 138 336 8.5E-10 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CIG75_RS01585 f90f34c166a5b7389d757938fdb8aad3 356 Gene3D G3DSA:1.10.3720.10 3 345 2.5E-17 T 28-03-2018 CIG75_RS01585 f90f34c166a5b7389d757938fdb8aad3 356 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 156 342 2.1E-12 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CIG75_RS05195 f81a5834ba64c61e5a58e15ac77d0f21 45 Pfam PF12841 YvrJ protein family 6 35 6.2E-10 T 28-03-2018 IPR024419 Protein of unknown function YvrJ CIG75_RS17565 8544c91ba435085a539140ea0f405050 404 PRINTS PR01988 Putative bacilysin exporter bacE signature 261 278 8.6E-8 T 28-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CIG75_RS17565 8544c91ba435085a539140ea0f405050 404 PRINTS PR01988 Putative bacilysin exporter bacE signature 141 162 8.6E-8 T 28-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CIG75_RS17565 8544c91ba435085a539140ea0f405050 404 PRINTS PR01988 Putative bacilysin exporter bacE signature 10 32 8.6E-8 T 28-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CIG75_RS17565 8544c91ba435085a539140ea0f405050 404 PRINTS PR01988 Putative bacilysin exporter bacE signature 371 394 8.6E-8 T 28-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CIG75_RS17565 8544c91ba435085a539140ea0f405050 404 PRINTS PR01988 Putative bacilysin exporter bacE signature 168 185 8.6E-8 T 28-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CIG75_RS17565 8544c91ba435085a539140ea0f405050 404 Pfam PF07690 Major Facilitator Superfamily 11 357 1.8E-30 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CIG75_RS17565 8544c91ba435085a539140ea0f405050 404 Gene3D G3DSA:1.20.1250.20 209 396 4.2E-15 T 28-03-2018 CIG75_RS17565 8544c91ba435085a539140ea0f405050 404 Gene3D G3DSA:1.20.1250.20 1 203 4.2E-18 T 28-03-2018 CIG75_RS17565 8544c91ba435085a539140ea0f405050 404 SUPERFAMILY SSF103473 8 395 1.7E-42 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS17565 8544c91ba435085a539140ea0f405050 404 ProSitePatterns PS00217 Sugar transport proteins signature 2. 320 345 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CIG75_RS17065 68ca269f91eaef41c4326e05314cb94b 512 SUPERFAMILY SSF53649 314 511 9.81E-68 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CIG75_RS17065 68ca269f91eaef41c4326e05314cb94b 512 SUPERFAMILY SSF53649 6 78 9.81E-68 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CIG75_RS17065 68ca269f91eaef41c4326e05314cb94b 512 Gene3D G3DSA:3.40.1450.10 78 315 1.2E-94 T 28-03-2018 CIG75_RS17065 68ca269f91eaef41c4326e05314cb94b 512 Pfam PF01676 Metalloenzyme superfamily 6 499 4.2E-76 T 28-03-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 CIG75_RS17065 68ca269f91eaef41c4326e05314cb94b 512 TIGRFAM TIGR01307 pgm_bpd_ind: phosphoglycerate mutase (2,3-diphosphoglycerate-independent) 6 511 2.1E-208 T 28-03-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CIG75_RS17065 68ca269f91eaef41c4326e05314cb94b 512 Hamap MF_01038 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [gpmI]. 5 512 48.197 T 28-03-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CIG75_RS17065 68ca269f91eaef41c4326e05314cb94b 512 PIRSF PIRSF001492 1 512 9.8E-202 T 28-03-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CIG75_RS17065 68ca269f91eaef41c4326e05314cb94b 512 Pfam PF06415 BPG-independent PGAM N-terminus (iPGM_N) 83 302 8.2E-82 T 28-03-2018 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CIG75_RS17065 68ca269f91eaef41c4326e05314cb94b 512 SUPERFAMILY SSF64158 78 313 1.57E-87 T 28-03-2018 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CIG75_RS17065 68ca269f91eaef41c4326e05314cb94b 512 Gene3D G3DSA:3.40.720.10 339 512 5.5E-4 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CIG75_RS18580 fb4cf9f3c1caefcd90e748695c2ef3c3 199 SUPERFAMILY SSF53335 3 177 1.04E-24 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CIG75_RS18580 fb4cf9f3c1caefcd90e748695c2ef3c3 199 Gene3D G3DSA:3.40.50.150 1 190 8.0E-16 T 28-03-2018 CIG75_RS18580 fb4cf9f3c1caefcd90e748695c2ef3c3 199 Pfam PF03848 Tellurite resistance protein TehB 34 180 1.8E-9 T 28-03-2018 IPR015985 Tellurite resistance methyltransferase TehB-like domain CIG75_RS11740 79226c11666fe15a4d1bbeb23c478948 90 Pfam PF05239 PRC-barrel domain 1 79 1.8E-13 T 28-03-2018 IPR027275 PRC-barrel domain CIG75_RS11740 79226c11666fe15a4d1bbeb23c478948 90 Gene3D G3DSA:2.30.30.240 1 78 3.1E-17 T 28-03-2018 CIG75_RS11740 79226c11666fe15a4d1bbeb23c478948 90 TIGRFAM TIGR02888 spore_YlmC_YmxH: sporulation protein, YlmC/YmxH family 2 74 1.5E-24 T 28-03-2018 IPR014238 Sporulation protein YlmC/YmxH CIG75_RS11740 79226c11666fe15a4d1bbeb23c478948 90 SUPERFAMILY SSF50346 1 75 3.14E-13 T 28-03-2018 IPR011033 PRC-barrel-like CIG75_RS10720 738b3ed404e23db959e0c129f89642bf 419 Pfam PF01420 Type I restriction modification DNA specificity domain 215 385 6.9E-15 T 28-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 CIG75_RS10720 738b3ed404e23db959e0c129f89642bf 419 Pfam PF01420 Type I restriction modification DNA specificity domain 7 175 3.4E-15 T 28-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 CIG75_RS10720 738b3ed404e23db959e0c129f89642bf 419 Gene3D G3DSA:3.90.220.20 214 366 7.4E-25 T 28-03-2018 CIG75_RS10720 738b3ed404e23db959e0c129f89642bf 419 Gene3D G3DSA:3.90.220.20 2 165 6.5E-28 T 28-03-2018 CIG75_RS10720 738b3ed404e23db959e0c129f89642bf 419 SUPERFAMILY SSF116734 6 200 1.42E-35 T 28-03-2018 CIG75_RS10720 738b3ed404e23db959e0c129f89642bf 419 Gene3D G3DSA:1.10.287.1120 166 213 3.0E-11 T 28-03-2018 CIG75_RS10720 738b3ed404e23db959e0c129f89642bf 419 SUPERFAMILY SSF116734 203 408 8.67E-34 T 28-03-2018 CIG75_RS18485 9d6a77da39ce7f778152f8d3cf60a723 207 TIGRFAM TIGR03570 NeuD_NnaD: sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family 5 201 4.9E-68 T 28-03-2018 IPR020019 Sialic acid O-acyltransferase NeuD-like CIG75_RS18485 9d6a77da39ce7f778152f8d3cf60a723 207 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 117 151 3.5E-4 T 28-03-2018 IPR001451 Hexapeptide repeat CIG75_RS18485 9d6a77da39ce7f778152f8d3cf60a723 207 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 153 185 3.6E-5 T 28-03-2018 IPR001451 Hexapeptide repeat CIG75_RS18485 9d6a77da39ce7f778152f8d3cf60a723 207 Gene3D G3DSA:2.160.10.10 74 207 5.6E-31 T 28-03-2018 CIG75_RS18485 9d6a77da39ce7f778152f8d3cf60a723 207 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 161 189 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CIG75_RS18485 9d6a77da39ce7f778152f8d3cf60a723 207 SUPERFAMILY SSF51161 3 205 7.21E-47 T 28-03-2018 IPR011004 Trimeric LpxA-like CIG75_RS18485 9d6a77da39ce7f778152f8d3cf60a723 207 Gene3D G3DSA:3.40.50.20 1 73 5.5E-16 T 28-03-2018 CIG75_RS09275 b10274230e2a62bd164b78a2e64186a3 202 PIRSF PIRSF029008 1 106 1.5E-24 T 28-03-2018 IPR008681 Negative regulator of genetic competence, MecA CIG75_RS09275 b10274230e2a62bd164b78a2e64186a3 202 PIRSF PIRSF029008 81 201 4.9E-22 T 28-03-2018 IPR008681 Negative regulator of genetic competence, MecA CIG75_RS09275 b10274230e2a62bd164b78a2e64186a3 202 Pfam PF05389 Negative regulator of genetic competence (MecA) 1 195 7.4E-42 T 28-03-2018 IPR008681 Negative regulator of genetic competence, MecA CIG75_RS03270 cf1313c2235d0d67593f47da670d504b 271 Pfam PF09922 Cell wall-active antibiotics response 4TMS YvqF 156 268 1.2E-30 T 28-03-2018 IPR024425 Cell wall-active antibiotics response 4TMS YvqF CIG75_RS03270 cf1313c2235d0d67593f47da670d504b 271 PIRSF PIRSF031509 22 271 3.2E-47 T 28-03-2018 IPR016975 Cell wall-active antibiotic response protein GO:0016021 CIG75_RS01360 02a57d9b363742c942bc76afb1dc6dd1 579 SUPERFAMILY SSF90123 2 316 3.4E-77 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CIG75_RS01360 02a57d9b363742c942bc76afb1dc6dd1 579 ProSitePatterns PS00211 ABC transporters family signature. 472 486 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS01360 02a57d9b363742c942bc76afb1dc6dd1 579 Pfam PF00005 ABC transporter 351 500 2.4E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS01360 02a57d9b363742c942bc76afb1dc6dd1 579 Gene3D G3DSA:3.40.50.300 323 576 2.1E-74 T 28-03-2018 CIG75_RS01360 02a57d9b363742c942bc76afb1dc6dd1 579 SMART SM00382 360 552 1.4E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS01360 02a57d9b363742c942bc76afb1dc6dd1 579 Pfam PF00664 ABC transporter transmembrane region 15 288 1.4E-44 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CIG75_RS01360 02a57d9b363742c942bc76afb1dc6dd1 579 SUPERFAMILY SSF52540 329 570 5.03E-86 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS01360 02a57d9b363742c942bc76afb1dc6dd1 579 Gene3D G3DSA:1.20.1560.10 1 322 5.8E-68 T 28-03-2018 CIG75_RS06390 092b64abfb029cdbfad1bac6cbdec9e0 412 Pfam PF02355 Protein export membrane protein 220 389 5.3E-12 T 28-03-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial CIG75_RS06390 092b64abfb029cdbfad1bac6cbdec9e0 412 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 125 386 7.9E-82 T 28-03-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 CIG75_RS06390 092b64abfb029cdbfad1bac6cbdec9e0 412 PRINTS PR00702 Acriflavin resistance protein family signature 288 312 1.9E-5 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CIG75_RS06390 092b64abfb029cdbfad1bac6cbdec9e0 412 PRINTS PR00702 Acriflavin resistance protein family signature 231 254 1.9E-5 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CIG75_RS06390 092b64abfb029cdbfad1bac6cbdec9e0 412 PRINTS PR00702 Acriflavin resistance protein family signature 363 386 1.9E-5 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CIG75_RS06390 092b64abfb029cdbfad1bac6cbdec9e0 412 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 155 379 3.1E-56 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CIG75_RS06390 092b64abfb029cdbfad1bac6cbdec9e0 412 SUPERFAMILY SSF82866 196 391 1.05E-32 T 28-03-2018 CIG75_RS06390 092b64abfb029cdbfad1bac6cbdec9e0 412 Gene3D G3DSA:1.20.1640.10 178 392 1.6E-26 T 28-03-2018 CIG75_RS06390 092b64abfb029cdbfad1bac6cbdec9e0 412 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 1 399 32.91 T 28-03-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 CIG75_RS07455 6435e035f5bca6fe5fbcfd25d87e3134 260 Pfam PF01497 Periplasmic binding protein 3 233 2.4E-43 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CIG75_RS07455 6435e035f5bca6fe5fbcfd25d87e3134 260 SUPERFAMILY SSF53807 2 258 3.92E-62 T 28-03-2018 CIG75_RS07455 6435e035f5bca6fe5fbcfd25d87e3134 260 Gene3D G3DSA:3.40.50.1980 1 106 2.2E-32 T 28-03-2018 CIG75_RS07455 6435e035f5bca6fe5fbcfd25d87e3134 260 Gene3D G3DSA:3.40.50.1980 107 260 3.6E-34 T 28-03-2018 CIG75_RS00165 78fcd329188b302ffb0638424e98a794 270 Pfam PF00348 Polyprenyl synthetase 98 202 3.3E-7 T 28-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 CIG75_RS00165 78fcd329188b302ffb0638424e98a794 270 SUPERFAMILY SSF48576 65 266 1.41E-13 T 28-03-2018 IPR008949 Isoprenoid synthase domain CIG75_RS00165 78fcd329188b302ffb0638424e98a794 270 Gene3D G3DSA:1.10.600.10 2 222 9.2E-14 T 28-03-2018 IPR008949 Isoprenoid synthase domain CIG75_RS00165 78fcd329188b302ffb0638424e98a794 270 Gene3D G3DSA:1.10.600.10 228 270 0.037 T 28-03-2018 IPR008949 Isoprenoid synthase domain CIG75_RS10300 1a0d419dc7dc77e0a0ffaa9ba284bbf1 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 194 214 3.7E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS10300 1a0d419dc7dc77e0a0ffaa9ba284bbf1 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 118 134 3.7E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS10300 1a0d419dc7dc77e0a0ffaa9ba284bbf1 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 71 82 3.7E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS10300 1a0d419dc7dc77e0a0ffaa9ba284bbf1 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 182 3.7E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS10300 1a0d419dc7dc77e0a0ffaa9ba284bbf1 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 3.7E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS10300 1a0d419dc7dc77e0a0ffaa9ba284bbf1 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 163 3.7E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS10300 1a0d419dc7dc77e0a0ffaa9ba284bbf1 238 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 131 159 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CIG75_RS10300 1a0d419dc7dc77e0a0ffaa9ba284bbf1 238 Gene3D G3DSA:3.40.50.720 1 43 2.3E-6 T 28-03-2018 CIG75_RS10300 1a0d419dc7dc77e0a0ffaa9ba284bbf1 238 Gene3D G3DSA:3.40.50.720 44 238 6.1E-61 T 28-03-2018 CIG75_RS10300 1a0d419dc7dc77e0a0ffaa9ba284bbf1 238 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 231 2.2E-67 T 28-03-2018 CIG75_RS10300 1a0d419dc7dc77e0a0ffaa9ba284bbf1 238 SUPERFAMILY SSF51735 6 231 7.2E-76 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS10300 1a0d419dc7dc77e0a0ffaa9ba284bbf1 238 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 71 82 4.2E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS10300 1a0d419dc7dc77e0a0ffaa9ba284bbf1 238 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 163 4.2E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS10300 1a0d419dc7dc77e0a0ffaa9ba284bbf1 238 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 124 132 4.2E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS14220 8fbf6fea9f60a8762dc5895d91376b11 412 Pfam PF00756 Putative esterase 193 407 1.2E-32 T 28-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 CIG75_RS14220 8fbf6fea9f60a8762dc5895d91376b11 412 Gene3D G3DSA:3.40.50.1820 169 412 1.4E-33 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS14220 8fbf6fea9f60a8762dc5895d91376b11 412 SUPERFAMILY SSF53474 177 410 2.6E-46 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS14220 8fbf6fea9f60a8762dc5895d91376b11 412 Gene3D G3DSA:2.60.40.10 32 152 8.6E-22 T 28-03-2018 IPR013783 Immunoglobulin-like fold CIG75_RS14220 8fbf6fea9f60a8762dc5895d91376b11 412 SUPERFAMILY SSF81296 33 144 1.16E-15 T 28-03-2018 IPR014756 Immunoglobulin E-set CIG75_RS10395 f81e7588176968acd9f65a42fdca1ce4 320 Pfam PF12706 Beta-lactamase superfamily domain 73 270 4.1E-34 T 28-03-2018 IPR001279 Metallo-beta-lactamase CIG75_RS10395 f81e7588176968acd9f65a42fdca1ce4 320 Gene3D G3DSA:3.60.15.10 23 318 3.0E-46 T 28-03-2018 IPR001279 Metallo-beta-lactamase CIG75_RS10395 f81e7588176968acd9f65a42fdca1ce4 320 PIRSF PIRSF038896 20 311 2.2E-71 T 28-03-2018 IPR024884 N-acyl-phosphatidylethanolamine-hydrolysing phospholipase D GO:0008270|GO:0070290 Reactome: R-HSA-2466712 CIG75_RS10395 f81e7588176968acd9f65a42fdca1ce4 320 SUPERFAMILY SSF56281 55 312 7.99E-34 T 28-03-2018 IPR001279 Metallo-beta-lactamase CIG75_RS05090 dd8a7aac8b13b4c21122912a2f04649f 195 Gene3D G3DSA:2.40.380.10 3 194 3.8E-27 T 28-03-2018 IPR007295 Domain of unknown function DUF402 CIG75_RS05090 dd8a7aac8b13b4c21122912a2f04649f 195 SUPERFAMILY SSF159234 23 187 3.66E-22 T 28-03-2018 IPR007295 Domain of unknown function DUF402 CIG75_RS05090 dd8a7aac8b13b4c21122912a2f04649f 195 Pfam PF04167 Protein of unknown function (DUF402) 80 143 2.1E-13 T 28-03-2018 IPR007295 Domain of unknown function DUF402 CIG75_RS04795 e8e3674be8eb1486ade7b4c884d4b052 72 SUPERFAMILY SSF53098 9 71 6.07E-6 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CIG75_RS04795 e8e3674be8eb1486ade7b4c884d4b052 72 Gene3D G3DSA:3.30.420.10 3 72 4.8E-4 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CIG75_RS13195 d0a3058b3388a12f5d22d57228f3b9e9 228 SUPERFAMILY SSF51419 2 225 3.93E-73 T 28-03-2018 IPR029066 PLP-binding barrel CIG75_RS13195 d0a3058b3388a12f5d22d57228f3b9e9 228 PIRSF PIRSF004848 1 228 4.2E-69 T 28-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein CIG75_RS13195 d0a3058b3388a12f5d22d57228f3b9e9 228 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 2 226 3.9E-56 T 28-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein CIG75_RS13195 d0a3058b3388a12f5d22d57228f3b9e9 228 Pfam PF01168 Alanine racemase, N-terminal domain 7 226 7.1E-19 T 28-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CIG75_RS13195 d0a3058b3388a12f5d22d57228f3b9e9 228 Gene3D G3DSA:3.20.20.10 1 228 1.6E-62 T 28-03-2018 IPR029066 PLP-binding barrel CIG75_RS13195 d0a3058b3388a12f5d22d57228f3b9e9 228 ProSitePatterns PS01211 Uncharacterized protein family UPF0001 signature. 76 90 - T 28-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein CIG75_RS15205 19f5617d4c6847037a8764560f1b18c3 189 SUPERFAMILY SSF51161 69 184 7.9E-37 T 28-03-2018 IPR011004 Trimeric LpxA-like CIG75_RS15205 19f5617d4c6847037a8764560f1b18c3 189 Gene3D G3DSA:2.160.10.10 9 187 3.6E-36 T 28-03-2018 CIG75_RS15205 19f5617d4c6847037a8764560f1b18c3 189 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 131 165 5.0E-11 T 28-03-2018 IPR001451 Hexapeptide repeat CIG75_RS15205 19f5617d4c6847037a8764560f1b18c3 189 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 139 167 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CIG75_RS04805 54f2fd06d3daa0e38b3ecfec2b98ffdf 201 Pfam PF01351 Ribonuclease HII 1 191 5.6E-23 T 28-03-2018 IPR024567 Ribonuclease HII/HIII domain CIG75_RS04805 54f2fd06d3daa0e38b3ecfec2b98ffdf 201 Gene3D G3DSA:3.30.420.10 1 201 3.4E-28 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CIG75_RS04805 54f2fd06d3daa0e38b3ecfec2b98ffdf 201 SUPERFAMILY SSF53098 1 195 3.95E-27 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CIG75_RS08090 c2ef54247e47cef4dd8c3c3c83da9dd4 225 SUPERFAMILY SSF63848 110 216 3.53E-31 T 28-03-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 CIG75_RS08090 c2ef54247e47cef4dd8c3c3c83da9dd4 225 Gene3D G3DSA:3.30.750.50 16 98 9.0E-18 T 28-03-2018 CIG75_RS08090 c2ef54247e47cef4dd8c3c3c83da9dd4 225 Gene3D G3DSA:2.160.20.70 99 218 1.7E-36 T 28-03-2018 CIG75_RS08090 c2ef54247e47cef4dd8c3c3c83da9dd4 225 Pfam PF03775 Septum formation inhibitor MinC, C-terminal domain 112 210 3.8E-31 T 28-03-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 CIG75_RS08090 c2ef54247e47cef4dd8c3c3c83da9dd4 225 Hamap MF_00267 Probable septum site-determining protein MinC [minC]. 15 215 21.494 T 28-03-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 CIG75_RS08770 a62009173991e7030d4291672720ab50 380 Gene3D G3DSA:3.90.870.10 1 211 3.6E-94 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CIG75_RS08770 a62009173991e7030d4291672720ab50 380 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 1 202 38.331 T 28-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CIG75_RS08770 a62009173991e7030d4291672720ab50 380 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 7 197 4.3E-83 T 28-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CIG75_RS08770 a62009173991e7030d4291672720ab50 380 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 1 198 1.8E-77 T 28-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CIG75_RS08770 a62009173991e7030d4291672720ab50 380 SUPERFAMILY SSF142695 203 367 1.31E-54 T 28-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CIG75_RS08770 a62009173991e7030d4291672720ab50 380 PIRSF PIRSF001259 1 377 1.1E-146 T 28-03-2018 CIG75_RS08770 a62009173991e7030d4291672720ab50 380 SUPERFAMILY SSF55821 3 205 1.19E-83 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CIG75_RS08770 a62009173991e7030d4291672720ab50 380 Pfam PF00925 GTP cyclohydrolase II 207 365 2.0E-48 T 28-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CIG75_RS12015 de1b80b44a5cbc3ad2b39b3a9080683d 76 Pfam PF06289 Flagellar protein (FlbD) 1 58 7.8E-25 T 28-03-2018 IPR009384 Flagellar CIG75_RS12415 0b7a1e4b2fd37d45212a85cbedc3bc07 191 SUPERFAMILY SSF53335 1 181 1.53E-50 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CIG75_RS12415 0b7a1e4b2fd37d45212a85cbedc3bc07 191 Pfam PF03602 Conserved hypothetical protein 95 1 182 4.8E-59 T 28-03-2018 CIG75_RS12415 0b7a1e4b2fd37d45212a85cbedc3bc07 191 PIRSF PIRSF004553 1 185 3.0E-51 T 28-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 CIG75_RS12415 0b7a1e4b2fd37d45212a85cbedc3bc07 191 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 2 183 1.1E-56 T 28-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 CIG75_RS12415 0b7a1e4b2fd37d45212a85cbedc3bc07 191 Gene3D G3DSA:3.40.50.150 1 185 1.3E-31 T 28-03-2018 CIG75_RS12415 0b7a1e4b2fd37d45212a85cbedc3bc07 191 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 117 123 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CIG75_RS07730 269e09542922e8e0607c261307052470 329 Gene3D G3DSA:3.40.50.1820 14 328 2.3E-36 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS07730 269e09542922e8e0607c261307052470 329 SUPERFAMILY SSF53474 2 325 4.66E-86 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS07730 269e09542922e8e0607c261307052470 329 Pfam PF00561 alpha/beta hydrolase fold 36 311 7.0E-24 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CIG75_RS07730 269e09542922e8e0607c261307052470 329 PIRSF PIRSF000443 1 328 3.2E-116 T 28-03-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 CIG75_RS07730 269e09542922e8e0607c261307052470 329 TIGRFAM TIGR01392 homoserO_Ac_trn: homoserine O-acetyltransferase 8 323 2.1E-110 T 28-03-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 CIG75_RS05595 aa3a6100c4934ceaddd9c94929b57504 304 Gene3D G3DSA:1.10.3720.10 31 292 8.3E-50 T 28-03-2018 CIG75_RS05595 aa3a6100c4934ceaddd9c94929b57504 304 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 120 304 2.0E-34 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CIG75_RS05595 aa3a6100c4934ceaddd9c94929b57504 304 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 27 79 3.4E-17 T 28-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CIG75_RS05595 aa3a6100c4934ceaddd9c94929b57504 304 SUPERFAMILY SSF161098 97 303 3.49E-31 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CIG75_RS00995 d00fda96338d2e0411cd4aa80c540ea7 134 Pfam PF08570 Protein of unknown function (DUF1761) 11 129 3.1E-18 T 28-03-2018 IPR013879 Protein of unknown function DUF1761 CIG75_RS14595 5df3fdd17aef3a412bd46b5c0468bae8 149 Gene3D G3DSA:3.10.490.10 2 149 3.8E-15 T 28-03-2018 CIG75_RS14595 5df3fdd17aef3a412bd46b5c0468bae8 149 SUPERFAMILY SSF110857 3 118 7.98E-9 T 28-03-2018 IPR013024 Gamma-glutamyl cyclotransferase-like CIG75_RS14720 5c39d8209844b35261d9ba497061b9b7 160 Gene3D G3DSA:1.10.3830.10 3 115 9.8E-39 T 28-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 CIG75_RS14720 5c39d8209844b35261d9ba497061b9b7 160 Pfam PF01219 Prokaryotic diacylglycerol kinase 12 113 1.3E-34 T 28-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 CIG75_RS17330 32f6e487ba7465cc51ac458f59818066 480 Gene3D G3DSA:3.30.1490.20 151 245 1.5E-10 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CIG75_RS17330 32f6e487ba7465cc51ac458f59818066 480 Gene3D G3DSA:3.40.50.20 33 150 0.0019 T 28-03-2018 CIG75_RS17330 32f6e487ba7465cc51ac458f59818066 480 SUPERFAMILY SSF56059 124 217 8.49E-33 T 28-03-2018 CIG75_RS17330 32f6e487ba7465cc51ac458f59818066 480 SUPERFAMILY SSF56059 244 388 8.49E-33 T 28-03-2018 CIG75_RS17330 32f6e487ba7465cc51ac458f59818066 480 Pfam PF13535 ATP-grasp domain 181 353 3.8E-12 T 28-03-2018 CIG75_RS17330 32f6e487ba7465cc51ac458f59818066 480 Gene3D G3DSA:3.30.470.20 246 441 1.6E-18 T 28-03-2018 CIG75_RS02770 4038a97686f197314f10e3916702b4fb 228 Gene3D G3DSA:1.10.150.240 17 92 5.8E-21 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CIG75_RS02770 4038a97686f197314f10e3916702b4fb 228 SUPERFAMILY SSF56784 3 226 1.68E-41 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS02770 4038a97686f197314f10e3916702b4fb 228 TIGRFAM TIGR02254 YjjG/YfnB: noncanonical pyrimidine nucleotidase, YjjG family 4 227 6.1E-86 T 28-03-2018 IPR011951 HAD-superfamily hydrolase, subfamily IA, YjjG/YfnB GO:0016787 CIG75_RS02770 4038a97686f197314f10e3916702b4fb 228 Gene3D G3DSA:3.40.50.1000 93 228 1.1E-25 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS02770 4038a97686f197314f10e3916702b4fb 228 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 96 194 2.3E-11 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CIG75_RS02770 4038a97686f197314f10e3916702b4fb 228 Pfam PF13419 Haloacid dehalogenase-like hydrolase 8 199 7.3E-21 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS07470 db3a2869b5d8dcc30b75a39220aa8cfe 431 SUPERFAMILY SSF54631 200 341 2.27E-31 T 28-03-2018 CIG75_RS07470 db3a2869b5d8dcc30b75a39220aa8cfe 431 SMART SM00116 282 330 1.3E-4 T 28-03-2018 IPR000644 CBS domain CIG75_RS07470 db3a2869b5d8dcc30b75a39220aa8cfe 431 SMART SM00116 219 268 100.0 T 28-03-2018 IPR000644 CBS domain CIG75_RS07470 db3a2869b5d8dcc30b75a39220aa8cfe 431 SMART SM01091 344 421 3.0E-20 T 28-03-2018 IPR005170 Transporter-associated domain CIG75_RS07470 db3a2869b5d8dcc30b75a39220aa8cfe 431 Gene3D G3DSA:3.30.465.10 338 421 1.9E-20 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CIG75_RS07470 db3a2869b5d8dcc30b75a39220aa8cfe 431 Pfam PF00571 CBS domain 280 330 5.9E-10 T 28-03-2018 IPR000644 CBS domain CIG75_RS07470 db3a2869b5d8dcc30b75a39220aa8cfe 431 Gene3D G3DSA:3.10.580.10 190 337 1.2E-33 T 28-03-2018 CIG75_RS07470 db3a2869b5d8dcc30b75a39220aa8cfe 431 Pfam PF03471 Transporter associated domain 346 420 3.7E-16 T 28-03-2018 IPR005170 Transporter-associated domain CIG75_RS07470 db3a2869b5d8dcc30b75a39220aa8cfe 431 Pfam PF01595 Domain of unknown function DUF21 2 195 1.8E-52 T 28-03-2018 IPR002550 Domain of unknown function DUF21 CIG75_RS07470 db3a2869b5d8dcc30b75a39220aa8cfe 431 SUPERFAMILY SSF56176 344 427 9.0E-18 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CIG75_RS11130 36dc7ff834e495fcfeef1acdb29e3c32 224 SUPERFAMILY SSF52540 20 215 1.23E-17 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS11130 36dc7ff834e495fcfeef1acdb29e3c32 224 Pfam PF02223 Thymidylate kinase 24 204 2.3E-8 T 28-03-2018 CIG75_RS11130 36dc7ff834e495fcfeef1acdb29e3c32 224 Gene3D G3DSA:3.40.50.300 21 212 3.8E-20 T 28-03-2018 CIG75_RS03615 254a267a6d8e21399df0fac76de4d5d8 475 Pfam PF13208 TerB N-terminal domain 27 182 1.4E-17 T 28-03-2018 IPR025266 TerB, N-terminal CIG75_RS03615 254a267a6d8e21399df0fac76de4d5d8 475 Pfam PF15615 TerB-C domain 304 462 6.2E-13 T 28-03-2018 IPR028932 TerB-C domain CIG75_RS17880 878e172cd30d9735b2089d65584a3d41 122 Pfam PF01903 CbiX 11 113 2.3E-18 T 28-03-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 CIG75_RS17880 878e172cd30d9735b2089d65584a3d41 122 SUPERFAMILY SSF53800 3 118 1.3E-24 T 28-03-2018 CIG75_RS17880 878e172cd30d9735b2089d65584a3d41 122 Gene3D G3DSA:3.40.50.1400 2 121 5.2E-23 T 28-03-2018 CIG75_RS01555 ebb5b7285a7f7b7258328069a86bd0b2 523 Pfam PF09043 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit 4 510 8.3E-266 T 28-03-2018 IPR015130 D-Lysine 5,6-aminomutase alpha subunit CIG75_RS01555 ebb5b7285a7f7b7258328069a86bd0b2 523 SUPERFAMILY SSF51703 1 513 3.92E-228 T 28-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CIG75_RS01555 ebb5b7285a7f7b7258328069a86bd0b2 523 Gene3D G3DSA:3.20.20.440 3 512 1.6E-247 T 28-03-2018 IPR015130 D-Lysine 5,6-aminomutase alpha subunit CIG75_RS13995 b518eb7eb1b4a516a9a7ac8b6fc4f86e 123 Gene3D G3DSA:1.10.260.40 1 122 5.4E-20 T 28-03-2018 CIG75_RS13995 b518eb7eb1b4a516a9a7ac8b6fc4f86e 123 SUPERFAMILY SSF47413 2 68 4.9E-18 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CIG75_RS13995 b518eb7eb1b4a516a9a7ac8b6fc4f86e 123 SMART SM00530 7 63 3.6E-15 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS13995 b518eb7eb1b4a516a9a7ac8b6fc4f86e 123 Pfam PF01381 Helix-turn-helix 8 63 1.3E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS11110 437cc7cd09b5f2cf4ff7451fd2949477 794 Gene3D G3DSA:3.40.50.880 167 330 3.5E-20 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CIG75_RS11110 437cc7cd09b5f2cf4ff7451fd2949477 794 SUPERFAMILY SSF52317 162 328 8.93E-15 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CIG75_RS19790 0f01bcde0a243493ac20d426223970ba 227 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 226 2.2E-109 T 28-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 CIG75_RS19790 0f01bcde0a243493ac20d426223970ba 227 Gene3D G3DSA:3.30.190.20 149 227 6.5E-23 T 28-03-2018 CIG75_RS19790 0f01bcde0a243493ac20d426223970ba 227 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 227 44.371 T 28-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 CIG75_RS19790 0f01bcde0a243493ac20d426223970ba 227 Gene3D G3DSA:3.40.50.790 68 148 1.5E-38 T 28-03-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich CIG75_RS19790 0f01bcde0a243493ac20d426223970ba 227 SUPERFAMILY SSF56808 6 226 2.22E-87 T 28-03-2018 IPR023674 Ribosomal protein L1-like CIG75_RS19790 0f01bcde0a243493ac20d426223970ba 227 Pfam PF00687 Ribosomal protein L1p/L10e family 30 220 7.8E-59 T 28-03-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein CIG75_RS19790 0f01bcde0a243493ac20d426223970ba 227 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 28-03-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CIG75_RS19790 0f01bcde0a243493ac20d426223970ba 227 PIRSF PIRSF002155 1 227 2.1E-84 T 28-03-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CIG75_RS15645 bd79c1caf51d3aad0f113b88d36cbc4e 108 Pfam PF09685 Domain of unknown function (DUF4870) 9 103 1.1E-21 T 28-03-2018 IPR019109 Protein of unknown function DUF4870 CIG75_RS13835 ed35dcc25a0f049c5482170fde612a80 576 PIRSF PIRSF003128 1 574 5.6E-179 T 28-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 CIG75_RS13835 ed35dcc25a0f049c5482170fde612a80 576 SUPERFAMILY SSF52540 4 50 2.76E-25 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS13835 ed35dcc25a0f049c5482170fde612a80 576 SUPERFAMILY SSF52540 307 524 2.76E-25 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS13835 ed35dcc25a0f049c5482170fde612a80 576 Gene3D G3DSA:3.40.50.300 1 181 3.9E-24 T 28-03-2018 CIG75_RS13835 ed35dcc25a0f049c5482170fde612a80 576 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 569 1.6E-176 T 28-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 CIG75_RS13835 ed35dcc25a0f049c5482170fde612a80 576 Pfam PF02463 RecF/RecN/SMC N terminal domain 1 528 1.2E-18 T 28-03-2018 IPR003395 RecF/RecN/SMC, N-terminal CIG75_RS13835 ed35dcc25a0f049c5482170fde612a80 576 SUPERFAMILY SSF52540 1 220 7.5E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS13835 ed35dcc25a0f049c5482170fde612a80 576 Gene3D G3DSA:3.40.50.300 207 543 1.6E-17 T 28-03-2018 CIG75_RS08385 90654c7a1ff31ede5b9f0c5bdb5c92f0 385 Gene3D G3DSA:3.20.20.80 27 385 2.5E-57 T 28-03-2018 CIG75_RS08385 90654c7a1ff31ede5b9f0c5bdb5c92f0 385 SMART SM00636 68 371 3.7E-26 T 28-03-2018 IPR011583 Chitinase II GO:0008061 CIG75_RS08385 90654c7a1ff31ede5b9f0c5bdb5c92f0 385 Pfam PF00704 Glycosyl hydrolases family 18 70 369 2.4E-35 T 28-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 CIG75_RS08385 90654c7a1ff31ede5b9f0c5bdb5c92f0 385 SUPERFAMILY SSF51445 69 287 2.95E-47 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CIG75_RS08385 90654c7a1ff31ede5b9f0c5bdb5c92f0 385 SUPERFAMILY SSF51445 343 377 2.95E-47 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CIG75_RS17385 518e51503abc625ba150beda5481049f 663 Gene3D G3DSA:3.40.50.300 16 419 2.8E-33 T 28-03-2018 CIG75_RS17385 518e51503abc625ba150beda5481049f 663 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 9 661 0.0 T 28-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 CIG75_RS17385 518e51503abc625ba150beda5481049f 663 Gene3D G3DSA:3.40.50.300 420 593 6.7E-30 T 28-03-2018 CIG75_RS17385 518e51503abc625ba150beda5481049f 663 Gene3D G3DSA:4.10.860.10 596 663 9.5E-15 T 28-03-2018 IPR001943 UVR domain GO:0005515 CIG75_RS17385 518e51503abc625ba150beda5481049f 663 Pfam PF02151 UvrB/uvrC motif 628 662 1.2E-7 T 28-03-2018 IPR001943 UVR domain GO:0005515 CIG75_RS17385 518e51503abc625ba150beda5481049f 663 Pfam PF04851 Type III restriction enzyme, res subunit 17 141 1.0E-11 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CIG75_RS17385 518e51503abc625ba150beda5481049f 663 Pfam PF12344 Ultra-violet resistance protein B 556 598 6.7E-22 T 28-03-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain CIG75_RS17385 518e51503abc625ba150beda5481049f 663 Pfam PF00271 Helicase conserved C-terminal domain 442 549 5.8E-17 T 28-03-2018 IPR001650 Helicase, C-terminal CIG75_RS17385 518e51503abc625ba150beda5481049f 663 SUPERFAMILY SSF52540 38 87 3.84E-34 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS17385 518e51503abc625ba150beda5481049f 663 SUPERFAMILY SSF52540 463 575 3.84E-34 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS17385 518e51503abc625ba150beda5481049f 663 SUPERFAMILY SSF46600 617 662 1.02E-10 T 28-03-2018 IPR001943 UVR domain GO:0005515 CIG75_RS17385 518e51503abc625ba150beda5481049f 663 SMART SM00487 14 429 2.2E-25 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CIG75_RS17385 518e51503abc625ba150beda5481049f 663 SUPERFAMILY SSF52540 9 419 1.39E-138 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS17385 518e51503abc625ba150beda5481049f 663 Hamap MF_00204 UvrABC system protein B [uvrB]. 8 663 43.908 T 28-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 CIG75_RS17385 518e51503abc625ba150beda5481049f 663 SMART SM00490 464 550 1.1E-18 T 28-03-2018 IPR001650 Helicase, C-terminal CIG75_RS01575 b3b7702257b7f720d2f922442b9198cd 309 Gene3D G3DSA:1.10.150.200 164 225 4.9E-9 T 28-03-2018 CIG75_RS01575 b3b7702257b7f720d2f922442b9198cd 309 Pfam PF01381 Helix-turn-helix 26 79 7.2E-14 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS01575 b3b7702257b7f720d2f922442b9198cd 309 Gene3D G3DSA:1.25.40.10 226 308 4.2E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS01575 b3b7702257b7f720d2f922442b9198cd 309 Gene3D G3DSA:1.10.260.40 8 163 6.8E-16 T 28-03-2018 CIG75_RS01575 b3b7702257b7f720d2f922442b9198cd 309 Pfam PF13181 Tetratricopeptide repeat 216 246 0.16 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS01575 b3b7702257b7f720d2f922442b9198cd 309 Pfam PF13181 Tetratricopeptide repeat 173 201 0.011 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS01575 b3b7702257b7f720d2f922442b9198cd 309 SMART SM00530 25 79 1.3E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS01575 b3b7702257b7f720d2f922442b9198cd 309 SMART SM00028 172 205 2.5 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS01575 b3b7702257b7f720d2f922442b9198cd 309 SMART SM00028 215 248 0.82 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS01575 b3b7702257b7f720d2f922442b9198cd 309 SUPERFAMILY SSF47413 21 80 1.63E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CIG75_RS01575 b3b7702257b7f720d2f922442b9198cd 309 SUPERFAMILY SSF48452 152 276 2.48E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS00495 4a1eac5972e2c587ebbd18c7556a6cd1 104 Pfam PF12643 MazG-like family 10 93 3.9E-28 T 28-03-2018 IPR025984 dCTP pyrophosphatase 1 GO:0009143|GO:0047429 KEGG: 00240+3.6.1.12|Reactome: R-HSA-499943 CIG75_RS09075 f7ee78de6d73c0b21fd6763ebdf0368e 223 SUPERFAMILY SSF48150 2 208 1.73E-70 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CIG75_RS09075 f7ee78de6d73c0b21fd6763ebdf0368e 223 PIRSF PIRSF001435 1 212 5.0E-54 T 28-03-2018 CIG75_RS09075 f7ee78de6d73c0b21fd6763ebdf0368e 223 Gene3D G3DSA:1.10.340.30 21 117 7.0E-27 T 28-03-2018 CIG75_RS09075 f7ee78de6d73c0b21fd6763ebdf0368e 223 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 187 203 1.8E-6 T 28-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 CIG75_RS09075 f7ee78de6d73c0b21fd6763ebdf0368e 223 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 187 203 - T 28-03-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CIG75_RS09075 f7ee78de6d73c0b21fd6763ebdf0368e 223 Hamap MF_00942 Endonuclease III [nth]. 1 209 38.336 T 28-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 CIG75_RS09075 f7ee78de6d73c0b21fd6763ebdf0368e 223 Pfam PF00633 Helix-hairpin-helix motif 102 127 6.2E-6 T 28-03-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 CIG75_RS09075 f7ee78de6d73c0b21fd6763ebdf0368e 223 TIGRFAM TIGR01083 nth: endonuclease III 9 194 2.2E-79 T 28-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 CIG75_RS09075 f7ee78de6d73c0b21fd6763ebdf0368e 223 ProSitePatterns PS01155 Endonuclease III family signature. 102 131 - T 28-03-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 CIG75_RS09075 f7ee78de6d73c0b21fd6763ebdf0368e 223 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 34 167 5.4E-21 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CIG75_RS09075 f7ee78de6d73c0b21fd6763ebdf0368e 223 SMART SM00478 38 185 1.7E-55 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CIG75_RS09075 f7ee78de6d73c0b21fd6763ebdf0368e 223 Gene3D G3DSA:1.10.1670.10 118 220 3.8E-32 T 28-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CIG75_RS05375 852e895b05b0cc3e5d938316acd3177e 211 Gene3D G3DSA:3.40.50.300 4 210 3.2E-38 T 28-03-2018 CIG75_RS05375 852e895b05b0cc3e5d938316acd3177e 211 Pfam PF00005 ABC transporter 23 158 2.6E-14 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS05375 852e895b05b0cc3e5d938316acd3177e 211 SMART SM00382 31 205 4.8E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS05375 852e895b05b0cc3e5d938316acd3177e 211 SUPERFAMILY SSF52540 7 209 8.91E-34 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS07875 0741ccc320ef8c2eba3444061d3e1117 254 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS07875 0741ccc320ef8c2eba3444061d3e1117 254 Gene3D G3DSA:3.40.50.300 2 226 7.3E-57 T 28-03-2018 CIG75_RS07875 0741ccc320ef8c2eba3444061d3e1117 254 SMART SM00382 32 212 3.6E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS07875 0741ccc320ef8c2eba3444061d3e1117 254 Pfam PF00005 ABC transporter 23 162 4.1E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS07875 0741ccc320ef8c2eba3444061d3e1117 254 SUPERFAMILY SSF52540 4 215 1.42E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS08710 87f8f97240f4f406c877b1fda2137795 152 TIGRFAM TIGR02838 spore_V_AC: stage V sporulation protein AC 10 149 3.3E-62 T 28-03-2018 IPR014203 Sporulation stage V, protein AC CIG75_RS08710 87f8f97240f4f406c877b1fda2137795 152 Pfam PF03862 SpoVAC/SpoVAEB sporulation membrane protein 27 144 5.0E-40 T 28-03-2018 IPR005562 SpoVA CIG75_RS00730 c958116d1d606d7b4d4d3353682a19cc 145 Gene3D G3DSA:3.10.450.50 2 136 5.6E-16 T 28-03-2018 CIG75_RS00730 c958116d1d606d7b4d4d3353682a19cc 145 Pfam PF13474 SnoaL-like domain 10 133 1.4E-15 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CIG75_RS00730 c958116d1d606d7b4d4d3353682a19cc 145 SUPERFAMILY SSF54427 2 133 3.09E-17 T 28-03-2018 IPR032710 NTF2-like domain CIG75_RS06360 96f44156de1c31322c059a32c14c3443 132 TIGRFAM TIGR04086 TIGR04086_membr: putative membrane protein, TIGR04086 family 17 130 1.3E-25 T 28-03-2018 IPR023804 Protein of unknown function DUF3792, transmembrane CIG75_RS06360 96f44156de1c31322c059a32c14c3443 132 Pfam PF12670 Protein of unknown function (DUF3792) 17 127 3.9E-21 T 28-03-2018 IPR023804 Protein of unknown function DUF3792, transmembrane CIG75_RS00620 9c88bd0a97e1f76e7a8106517d802bfc 356 Pfam PF01939 Endonuclease NucS 24 95 9.0E-7 T 28-03-2018 IPR002793 Endonuclease NucS CIG75_RS09680 a4055bfda108d1bf4cc20a695c2bbdfd 112 Gene3D G3DSA:1.10.760.10 22 112 1.5E-14 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CIG75_RS09680 a4055bfda108d1bf4cc20a695c2bbdfd 112 SUPERFAMILY SSF46626 11 110 4.44E-17 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CIG75_RS09680 a4055bfda108d1bf4cc20a695c2bbdfd 112 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 39 107 1.5E-9 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CIG75_RS09465 811ec7bd2efc3f6323fc2ef1f7da3013 499 Gene3D G3DSA:1.10.10.10 5 41 0.0017 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS09465 811ec7bd2efc3f6323fc2ef1f7da3013 499 Gene3D G3DSA:3.30.420.10 117 326 4.2E-17 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CIG75_RS09465 811ec7bd2efc3f6323fc2ef1f7da3013 499 Pfam PF00665 Integrase core domain 127 254 2.5E-14 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CIG75_RS09465 811ec7bd2efc3f6323fc2ef1f7da3013 499 SUPERFAMILY SSF53098 124 277 6.32E-8 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CIG75_RS00470 a2b5de9a5bf5b5a7396960622a46ac34 194 Pfam PF00226 DnaJ domain 142 190 2.9E-12 T 28-03-2018 IPR001623 DnaJ domain CIG75_RS00470 a2b5de9a5bf5b5a7396960622a46ac34 194 PRINTS PR00625 DnaJ domain signature 161 176 2.8E-7 T 28-03-2018 IPR001623 DnaJ domain CIG75_RS00470 a2b5de9a5bf5b5a7396960622a46ac34 194 PRINTS PR00625 DnaJ domain signature 143 161 2.8E-7 T 28-03-2018 IPR001623 DnaJ domain CIG75_RS00470 a2b5de9a5bf5b5a7396960622a46ac34 194 SUPERFAMILY SSF46565 109 190 5.36E-16 T 28-03-2018 IPR001623 DnaJ domain CIG75_RS00470 a2b5de9a5bf5b5a7396960622a46ac34 194 Gene3D G3DSA:1.10.287.110 140 192 1.1E-15 T 28-03-2018 IPR001623 DnaJ domain CIG75_RS00470 a2b5de9a5bf5b5a7396960622a46ac34 194 SMART SM00271 140 194 3.3E-13 T 28-03-2018 IPR001623 DnaJ domain CIG75_RS00310 f4bd828a8b703a12b01852e959d77442 81 Pfam PF03698 Uncharacterised protein family (UPF0180) 2 78 1.2E-27 T 28-03-2018 IPR005370 Uncharacterised protein family UPF0180 CIG75_RS00310 f4bd828a8b703a12b01852e959d77442 81 ProDom PD059670 UPF0180 YKUS BA1413/GBAA1413/BAS1304 YKUS-LIKE BT9727_1277 BCE1513 GK1051 BH2667 ABC2430 BCE33L1278 1 48 0.003 T 28-03-2018 IPR005370 Uncharacterised protein family UPF0180 CIG75_RS18025 5fbb87ac147487e471de17a9989d8f26 227 Pfam PF03741 Integral membrane protein TerC family 13 183 4.8E-45 T 28-03-2018 IPR005496 Integral membrane protein TerC GO:0016021 CIG75_RS18025 5fbb87ac147487e471de17a9989d8f26 227 TIGRFAM TIGR03717 R_switched_YjbE: integral membrane protein, YjbE family 10 184 1.3E-66 T 28-03-2018 IPR022301 Integral membrane protein YjbE CIG75_RS19115 83b683d5b83c88d84c6478fe739b9f32 97 Gene3D G3DSA:1.10.287.1080 1 94 5.5E-4 T 28-03-2018 CIG75_RS08725 b2e1c885a95a8564eb532296b2aa99b1 193 Pfam PF14097 Stage V sporulation protein AE1 5 185 7.7E-78 T 28-03-2018 IPR025914 Stage V sporulation protein AE CIG75_RS11750 e7125dafafb138e6a706a57ebf4a0d53 324 Pfam PF01522 Polysaccharide deacetylase 128 249 7.5E-28 T 28-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CIG75_RS11750 e7125dafafb138e6a706a57ebf4a0d53 324 Gene3D G3DSA:3.20.20.370 94 321 3.7E-53 T 28-03-2018 CIG75_RS11750 e7125dafafb138e6a706a57ebf4a0d53 324 SUPERFAMILY SSF88713 122 317 2.97E-57 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CIG75_RS02690 2f4b5803ccea69edf7a372c67d5753a9 444 SUPERFAMILY SSF55048 291 355 2.88E-11 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CIG75_RS02690 2f4b5803ccea69edf7a372c67d5753a9 444 Pfam PF00698 Acyl transferase domain 166 442 4.7E-56 T 28-03-2018 IPR014043 Acyl transferase CIG75_RS02690 2f4b5803ccea69edf7a372c67d5753a9 444 SUPERFAMILY SSF52151 356 442 5.75E-62 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CIG75_RS02690 2f4b5803ccea69edf7a372c67d5753a9 444 SUPERFAMILY SSF52151 163 292 5.75E-62 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CIG75_RS02690 2f4b5803ccea69edf7a372c67d5753a9 444 Gene3D G3DSA:3.40.366.10 350 444 3.7E-22 T 28-03-2018 CIG75_RS02690 2f4b5803ccea69edf7a372c67d5753a9 444 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 167 444 3.0E-82 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CIG75_RS02690 2f4b5803ccea69edf7a372c67d5753a9 444 Gene3D G3DSA:3.40.366.10 163 302 5.4E-42 T 28-03-2018 CIG75_RS02690 2f4b5803ccea69edf7a372c67d5753a9 444 Gene3D G3DSA:3.30.70.250 303 349 4.9E-15 T 28-03-2018 CIG75_RS06385 8b1c2bca1689c63fbae8b0861720d628 227 SUPERFAMILY SSF109604 29 185 2.33E-24 T 28-03-2018 CIG75_RS06385 8b1c2bca1689c63fbae8b0861720d628 227 Gene3D G3DSA:1.10.3210.10 3 215 2.0E-18 T 28-03-2018 CIG75_RS06385 8b1c2bca1689c63fbae8b0861720d628 227 Pfam PF01966 HD domain 42 139 4.6E-9 T 28-03-2018 IPR006674 HD domain CIG75_RS06385 8b1c2bca1689c63fbae8b0861720d628 227 SMART SM00471 37 152 7.3E-4 T 28-03-2018 IPR003607 HD/PDEase domain CIG75_RS01765 664ed6c2e7a9ad5cc58c69484a3d5255 322 SUPERFAMILY SSF56655 1 314 1.14E-111 T 28-03-2018 CIG75_RS01765 664ed6c2e7a9ad5cc58c69484a3d5255 322 TIGRFAM TIGR00330 glpX: fructose-1,6-bisphosphatase, class II 1 321 2.6E-136 T 28-03-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 CIG75_RS01765 664ed6c2e7a9ad5cc58c69484a3d5255 322 Pfam PF03320 Bacterial fructose-1,6-bisphosphatase, glpX-encoded 3 311 2.2E-145 T 28-03-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 CIG75_RS01765 664ed6c2e7a9ad5cc58c69484a3d5255 322 PIRSF PIRSF004532 1 322 2.6E-148 T 28-03-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 CIG75_RS01765 664ed6c2e7a9ad5cc58c69484a3d5255 322 Gene3D G3DSA:3.30.540.10 1 156 3.2E-56 T 28-03-2018 CIG75_RS01765 664ed6c2e7a9ad5cc58c69484a3d5255 322 Gene3D G3DSA:3.30.540.10 157 322 1.5E-61 T 28-03-2018 CIG75_RS17725 7151dbbe1318937e37f4178b980c7ff7 211 SUPERFAMILY SSF48317 9 207 4.58E-42 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CIG75_RS17725 7151dbbe1318937e37f4178b980c7ff7 211 Gene3D G3DSA:1.20.144.10 38 211 5.2E-31 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CIG75_RS17725 7151dbbe1318937e37f4178b980c7ff7 211 SMART SM00014 89 201 7.0E-27 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CIG75_RS17725 7151dbbe1318937e37f4178b980c7ff7 211 Pfam PF01569 PAP2 superfamily 89 208 1.1E-26 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CIG75_RS11035 79b73ef80438ebb92058cf8e261af3d3 255 Pfam PF00975 Thioesterase domain 23 247 8.1E-53 T 28-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CIG75_RS11035 79b73ef80438ebb92058cf8e261af3d3 255 Gene3D G3DSA:3.40.50.1820 2 253 2.0E-33 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS11035 79b73ef80438ebb92058cf8e261af3d3 255 SUPERFAMILY SSF53474 5 248 6.2E-55 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS06400 765f0a35a0158187a746eff47f83cc4e 796 Gene3D G3DSA:3.90.1640.10 66 242 5.3E-28 T 28-03-2018 CIG75_RS06400 765f0a35a0158187a746eff47f83cc4e 796 Pfam PF10141 Single-strand DNA-specific exonuclease, C terminal domain 570 790 5.6E-20 T 28-03-2018 IPR018779 Single-stranded-DNA-specific exonuclease RecJ, C-terminal CIG75_RS06400 765f0a35a0158187a746eff47f83cc4e 796 SUPERFAMILY SSF64182 61 454 7.19E-125 T 28-03-2018 CIG75_RS06400 765f0a35a0158187a746eff47f83cc4e 796 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 32 561 5.8E-177 T 28-03-2018 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 CIG75_RS06400 765f0a35a0158187a746eff47f83cc4e 796 Pfam PF02272 DHHA1 domain 318 441 6.4E-19 T 28-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CIG75_RS06400 765f0a35a0158187a746eff47f83cc4e 796 Pfam PF01368 DHH family 87 229 4.5E-10 T 28-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CIG75_RS12425 0aead831840f905d30c22fedc4382686 248 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 42 171 1.1E-12 T 28-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CIG75_RS12425 0aead831840f905d30c22fedc4382686 248 Gene3D G3DSA:1.10.530.10 37 173 1.1E-9 T 28-03-2018 CIG75_RS12425 0aead831840f905d30c22fedc4382686 248 Pfam PF00395 S-layer homology domain 193 236 1.8E-12 T 28-03-2018 IPR001119 S-layer homology domain CIG75_RS15250 69023c625939ebfc02dee9aff99a86a9 389 Gene3D G3DSA:3.60.21.10 41 388 1.1E-58 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CIG75_RS15250 69023c625939ebfc02dee9aff99a86a9 389 SUPERFAMILY SSF56300 57 318 8.35E-42 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CIG75_RS15250 69023c625939ebfc02dee9aff99a86a9 389 SMART SM00854 57 303 8.0E-92 T 28-03-2018 IPR019079 Capsule synthesis protein, CapA CIG75_RS15250 69023c625939ebfc02dee9aff99a86a9 389 Pfam PF09587 Bacterial capsule synthesis protein PGA_cap 57 303 1.8E-74 T 28-03-2018 IPR019079 Capsule synthesis protein, CapA CIG75_RS07560 961964a10119b5720940f4ec9dffa0b7 463 Pfam PF03553 Na+/H+ antiporter family 177 449 4.4E-24 T 28-03-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 CIG75_RS16695 213e7817591cee024e51026a03bbff14 323 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 43 320 2.5E-93 T 28-03-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 CIG75_RS16695 213e7817591cee024e51026a03bbff14 323 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 95 117 - T 28-03-2018 IPR030470 UbiA prenyltransferase conserved site CIG75_RS16695 213e7817591cee024e51026a03bbff14 323 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 40 322 18.461 T 28-03-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 CIG75_RS16695 213e7817591cee024e51026a03bbff14 323 Pfam PF01040 UbiA prenyltransferase family 58 302 2.8E-58 T 28-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 CIG75_RS01030 4ce2aabfd4c5dfba674d94d606e8dbc9 315 Gene3D G3DSA:1.10.3470.10 1 315 3.8E-40 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CIG75_RS01030 4ce2aabfd4c5dfba674d94d606e8dbc9 315 SUPERFAMILY SSF81345 13 311 4.84E-56 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CIG75_RS01030 4ce2aabfd4c5dfba674d94d606e8dbc9 315 Pfam PF01032 FecCD transport family 5 311 1.1E-52 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CIG75_RS07240 acfb3eb3ce5a6c24a73b49ff93f4a42d 265 Pfam PF00795 Carbon-nitrogen hydrolase 6 247 2.6E-53 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CIG75_RS07240 acfb3eb3ce5a6c24a73b49ff93f4a42d 265 SUPERFAMILY SSF56317 4 263 4.71E-82 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CIG75_RS07240 acfb3eb3ce5a6c24a73b49ff93f4a42d 265 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 144 164 - T 28-03-2018 IPR001110 Uncharacterised protein family UPF0012, conserved site CIG75_RS07240 acfb3eb3ce5a6c24a73b49ff93f4a42d 265 Gene3D G3DSA:3.60.110.10 1 263 8.5E-86 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CIG75_RS01925 1b96c0d81b8d4a73fdb92d71f524dedd 161 Hamap MF_01398 ATP synthase subunit b [atpF]. 1 139 12.535 T 28-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CIG75_RS01925 1b96c0d81b8d4a73fdb92d71f524dedd 161 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 11 156 1.5E-36 T 28-03-2018 IPR005864 ATP synthase, F0 complex, subunit b, bacterial GO:0015078|GO:0015986|GO:0045263 CIG75_RS01925 1b96c0d81b8d4a73fdb92d71f524dedd 161 Pfam PF00430 ATP synthase B/B' CF(0) 7 137 4.1E-34 T 28-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CIG75_RS01925 1b96c0d81b8d4a73fdb92d71f524dedd 161 SUPERFAMILY SSF81573 65 122 3.92E-7 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain CIG75_RS01925 1b96c0d81b8d4a73fdb92d71f524dedd 161 Gene3D G3DSA:1.20.5.620 63 123 7.1E-6 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain CIG75_RS14245 ed7c7a2749020571dc6ea91de2b907fa 231 Gene3D G3DSA:2.20.25.10 192 230 1.4E-12 T 28-03-2018 CIG75_RS14245 ed7c7a2749020571dc6ea91de2b907fa 231 Pfam PF04397 LytTr DNA-binding domain 135 229 7.0E-26 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CIG75_RS14245 ed7c7a2749020571dc6ea91de2b907fa 231 Gene3D G3DSA:3.30.450.20 1 114 5.6E-5 T 28-03-2018 CIG75_RS14245 ed7c7a2749020571dc6ea91de2b907fa 231 SMART SM00850 131 230 2.0E-25 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CIG75_RS14245 ed7c7a2749020571dc6ea91de2b907fa 231 Gene3D G3DSA:2.40.50.40 121 190 1.2E-15 T 28-03-2018 CIG75_RS07495 92029319795417cc0ab510128b3ba984 333 SUPERFAMILY SSF109604 121 248 1.52E-13 T 28-03-2018 CIG75_RS07495 92029319795417cc0ab510128b3ba984 333 Pfam PF01966 HD domain 127 229 3.9E-8 T 28-03-2018 IPR006674 HD domain CIG75_RS07495 92029319795417cc0ab510128b3ba984 333 Gene3D G3DSA:1.10.3210.10 120 274 1.4E-19 T 28-03-2018 CIG75_RS18930 87e6483998551253144c5d8d46012828 137 Gene3D G3DSA:3.10.450.40 12 135 2.0E-16 T 28-03-2018 CIG75_RS18930 87e6483998551253144c5d8d46012828 137 SUPERFAMILY SSF160719 36 131 7.06E-9 T 28-03-2018 CIG75_RS18930 87e6483998551253144c5d8d46012828 137 ProDom PD033094 XKDS PHAGE-LIKE PBSX ELEMENT PHAGE LIN1286 RELATED YQBS 21 133 8.0E-26 T 28-03-2018 IPR020288 Protein of unknown function DUF2634 CIG75_RS18930 87e6483998551253144c5d8d46012828 137 Pfam PF10934 Protein of unknown function (DUF2634) 30 120 7.4E-27 T 28-03-2018 IPR020288 Protein of unknown function DUF2634 CIG75_RS06970 5b5d3d0790f55ec663b0a1338c828dc1 95 Hamap MF_01448 UPF0473 protein . 6 85 13.257 T 28-03-2018 IPR009711 Uncharacterised protein family UPF0473 CIG75_RS06970 5b5d3d0790f55ec663b0a1338c828dc1 95 Pfam PF06949 Protein of unknown function (DUF1292) 15 83 6.9E-18 T 28-03-2018 IPR009711 Uncharacterised protein family UPF0473 CIG75_RS03435 279ce22cbf941af149672e367eb6dfc5 353 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 8 292 2.3E-52 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CIG75_RS03435 279ce22cbf941af149672e367eb6dfc5 353 SUPERFAMILY SSF53686 4 304 2.36E-71 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CIG75_RS03435 279ce22cbf941af149672e367eb6dfc5 353 Gene3D G3DSA:3.40.50.1100 144 305 5.7E-38 T 28-03-2018 CIG75_RS03435 279ce22cbf941af149672e367eb6dfc5 353 Gene3D G3DSA:3.40.50.1100 36 143 6.0E-21 T 28-03-2018 CIG75_RS17220 31f63073516decd68d20aea30e31caa5 161 Gene3D G3DSA:3.40.30.10 2 160 1.1E-42 T 28-03-2018 CIG75_RS17220 31f63073516decd68d20aea30e31caa5 161 Pfam PF00255 Glutathione peroxidase 4 110 1.2E-37 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CIG75_RS17220 31f63073516decd68d20aea30e31caa5 161 PIRSF PIRSF000303 1 161 3.3E-60 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CIG75_RS17220 31f63073516decd68d20aea30e31caa5 161 SUPERFAMILY SSF52833 3 158 2.08E-54 T 28-03-2018 IPR012336 Thioredoxin-like fold CIG75_RS17220 31f63073516decd68d20aea30e31caa5 161 PRINTS PR01011 Glutathione peroxidase family signature 120 129 6.7E-18 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CIG75_RS17220 31f63073516decd68d20aea30e31caa5 161 PRINTS PR01011 Glutathione peroxidase family signature 57 73 6.7E-18 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CIG75_RS17220 31f63073516decd68d20aea30e31caa5 161 PRINTS PR01011 Glutathione peroxidase family signature 22 39 6.7E-18 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CIG75_RS16020 9ee5c27b50128e3535f7d57d3704186c 199 SMART SM01118 2 192 1.5E-16 T 28-03-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 CIG75_RS16020 9ee5c27b50128e3535f7d57d3704186c 199 SUPERFAMILY SSF55154 1 195 8.83E-25 T 28-03-2018 IPR033469 CYTH-like domain Reactome: R-HSA-196819 CIG75_RS16020 9ee5c27b50128e3535f7d57d3704186c 199 Pfam PF01928 CYTH domain 3 184 5.2E-15 T 28-03-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 CIG75_RS16020 9ee5c27b50128e3535f7d57d3704186c 199 Gene3D G3DSA:2.40.320.10 3 197 7.5E-29 T 28-03-2018 CIG75_RS07440 fda4780756eb6bac15a87bbdbde50bba 260 Gene3D G3DSA:1.10.12.10 221 258 8.0E-15 T 28-03-2018 IPR014748 Crontonase, C-terminal CIG75_RS07440 fda4780756eb6bac15a87bbdbde50bba 260 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 101 121 - T 28-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CIG75_RS07440 fda4780756eb6bac15a87bbdbde50bba 260 SUPERFAMILY SSF52096 8 260 2.49E-84 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CIG75_RS07440 fda4780756eb6bac15a87bbdbde50bba 260 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 259 7.3E-63 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CIG75_RS07440 fda4780756eb6bac15a87bbdbde50bba 260 Gene3D G3DSA:3.90.226.10 4 220 1.4E-72 T 28-03-2018 CIG75_RS08540 826a901cbdeda507251fa23a739a5a8c 395 SUPERFAMILY SSF89550 6 247 1.1E-11 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CIG75_RS08540 826a901cbdeda507251fa23a739a5a8c 395 Gene3D G3DSA:3.20.20.140 1 258 6.6E-11 T 28-03-2018 CIG75_RS08540 826a901cbdeda507251fa23a739a5a8c 395 Pfam PF13263 PHP-associated 199 246 1.2E-6 T 28-03-2018 CIG75_RS08540 826a901cbdeda507251fa23a739a5a8c 395 SUPERFAMILY SSF47781 314 373 1.21E-9 T 28-03-2018 IPR010994 RuvA domain 2-like CIG75_RS08540 826a901cbdeda507251fa23a739a5a8c 395 Gene3D G3DSA:1.10.150.20 325 378 7.6E-10 T 28-03-2018 CIG75_RS02445 b658a7acc6a89edb0f90b49495ca0728 353 Pfam PF00571 CBS domain 63 116 4.6E-5 T 28-03-2018 IPR000644 CBS domain CIG75_RS02445 b658a7acc6a89edb0f90b49495ca0728 353 Pfam PF00571 CBS domain 7 53 4.3E-5 T 28-03-2018 IPR000644 CBS domain CIG75_RS02445 b658a7acc6a89edb0f90b49495ca0728 353 SUPERFAMILY SSF54631 6 57 7.06E-5 T 28-03-2018 CIG75_RS02445 b658a7acc6a89edb0f90b49495ca0728 353 Gene3D G3DSA:3.90.550.10 119 352 2.0E-56 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CIG75_RS02445 b658a7acc6a89edb0f90b49495ca0728 353 Gene3D G3DSA:3.10.580.10 1 118 2.7E-18 T 28-03-2018 CIG75_RS02445 b658a7acc6a89edb0f90b49495ca0728 353 SUPERFAMILY SSF53448 48 348 6.57E-70 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CIG75_RS02445 b658a7acc6a89edb0f90b49495ca0728 353 Pfam PF00483 Nucleotidyl transferase 124 343 3.8E-38 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CIG75_RS11515 4b2396587b6e7619f13a66cd1fc0b4b9 298 Pfam PF03466 LysR substrate binding domain 87 292 1.1E-54 T 28-03-2018 IPR005119 LysR, substrate-binding CIG75_RS11515 4b2396587b6e7619f13a66cd1fc0b4b9 298 Gene3D G3DSA:1.10.10.10 1 83 2.0E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS11515 4b2396587b6e7619f13a66cd1fc0b4b9 298 SUPERFAMILY SSF53850 87 296 6.79E-53 T 28-03-2018 CIG75_RS11515 4b2396587b6e7619f13a66cd1fc0b4b9 298 Gene3D G3DSA:3.40.190.10 177 265 2.5E-26 T 28-03-2018 CIG75_RS11515 4b2396587b6e7619f13a66cd1fc0b4b9 298 Gene3D G3DSA:3.40.190.10 88 176 1.1E-24 T 28-03-2018 CIG75_RS11515 4b2396587b6e7619f13a66cd1fc0b4b9 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.2E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CIG75_RS11515 4b2396587b6e7619f13a66cd1fc0b4b9 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 4.0E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CIG75_RS11515 4b2396587b6e7619f13a66cd1fc0b4b9 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 4.0E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CIG75_RS11515 4b2396587b6e7619f13a66cd1fc0b4b9 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 4.0E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CIG75_RS11515 4b2396587b6e7619f13a66cd1fc0b4b9 298 SUPERFAMILY SSF46785 2 110 4.87E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS02925 7642a0a7c5a75c9424dbc4d8c641f755 420 PIRSF PIRSF037118 2 420 1.7E-138 T 28-03-2018 IPR017115 Tellurite resistance, TerA CIG75_RS02925 7642a0a7c5a75c9424dbc4d8c641f755 420 Gene3D G3DSA:2.60.60.30 19 176 3.6E-45 T 28-03-2018 CIG75_RS02925 7642a0a7c5a75c9424dbc4d8c641f755 420 Gene3D G3DSA:2.60.60.30 242 405 4.4E-26 T 28-03-2018 CIG75_RS02925 7642a0a7c5a75c9424dbc4d8c641f755 420 Pfam PF02342 TerD domain 1 177 3.4E-59 T 28-03-2018 IPR003325 TerD domain GO:0006950 CIG75_RS04365 40d3e6c79e99420e9e413255b1357a1c 199 SUPERFAMILY SSF88659 110 183 2.8E-14 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS04365 40d3e6c79e99420e9e413255b1357a1c 199 Gene3D G3DSA:1.10.1740.10 10 96 1.0E-21 T 28-03-2018 CIG75_RS04365 40d3e6c79e99420e9e413255b1357a1c 199 SUPERFAMILY SSF88946 14 104 3.77E-23 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS04365 40d3e6c79e99420e9e413255b1357a1c 199 Pfam PF04542 Sigma-70 region 2 26 90 6.1E-14 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS04365 40d3e6c79e99420e9e413255b1357a1c 199 Gene3D G3DSA:1.10.10.10 109 199 2.0E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS04365 40d3e6c79e99420e9e413255b1357a1c 199 Pfam PF08281 Sigma-70, region 4 127 178 2.4E-12 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS04365 40d3e6c79e99420e9e413255b1357a1c 199 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 22 180 5.9E-29 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS05450 18365121948259b7eecdb9a01da82105 488 Gene3D G3DSA:3.40.50.10770 2 202 1.8E-22 T 28-03-2018 CIG75_RS05450 18365121948259b7eecdb9a01da82105 488 Pfam PF09670 CRISPR-associated protein (Cas_Cas02710) 106 458 2.1E-46 T 28-03-2018 CIG75_RS05450 18365121948259b7eecdb9a01da82105 488 TIGRFAM TIGR02710 TIGR02710: CRISPR-associated protein, TIGR02710 family 112 458 2.9E-48 T 28-03-2018 IPR014082 CRISPR-associated protein, Cas02710 CIG75_RS04010 a4022eb1d7d0c4a55e0a00f2750fd77c 206 Pfam PF12833 Helix-turn-helix domain 111 188 1.9E-21 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CIG75_RS04010 a4022eb1d7d0c4a55e0a00f2750fd77c 206 Gene3D G3DSA:3.40.10.10 8 69 9.2E-23 T 28-03-2018 IPR035451 Ada-like domain CIG75_RS04010 a4022eb1d7d0c4a55e0a00f2750fd77c 206 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 142 184 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CIG75_RS04010 a4022eb1d7d0c4a55e0a00f2750fd77c 206 SUPERFAMILY SSF46689 142 188 9.41E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CIG75_RS04010 a4022eb1d7d0c4a55e0a00f2750fd77c 206 SUPERFAMILY SSF57884 14 96 1.7E-29 T 28-03-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 CIG75_RS04010 a4022eb1d7d0c4a55e0a00f2750fd77c 206 Pfam PF02805 Metal binding domain of Ada 17 80 3.3E-28 T 28-03-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 CIG75_RS04010 a4022eb1d7d0c4a55e0a00f2750fd77c 206 Gene3D G3DSA:1.10.10.60 140 191 3.7E-12 T 28-03-2018 CIG75_RS04010 a4022eb1d7d0c4a55e0a00f2750fd77c 206 Gene3D G3DSA:1.10.10.60 70 139 5.3E-16 T 28-03-2018 CIG75_RS04010 a4022eb1d7d0c4a55e0a00f2750fd77c 206 SUPERFAMILY SSF46689 89 140 1.12E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CIG75_RS04010 a4022eb1d7d0c4a55e0a00f2750fd77c 206 PIRSF PIRSF000408 4 196 3.7E-76 T 28-03-2018 IPR016220 Methylphosphotriester-DNA alkyltransferase, AdaA CIG75_RS04010 a4022eb1d7d0c4a55e0a00f2750fd77c 206 SMART SM00342 105 188 1.5E-28 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CIG75_RS09580 ddc76a7064fd3a75d3e2737cddb4f935 562 SMART SM00327 387 562 1.5E-17 T 28-03-2018 IPR002035 von Willebrand factor, type A CIG75_RS09580 ddc76a7064fd3a75d3e2737cddb4f935 562 Gene3D G3DSA:3.40.190.10 3 359 4.0E-6 T 28-03-2018 CIG75_RS09580 ddc76a7064fd3a75d3e2737cddb4f935 562 Pfam PF13531 Bacterial extracellular solute-binding protein 107 353 1.6E-14 T 28-03-2018 CIG75_RS09580 ddc76a7064fd3a75d3e2737cddb4f935 562 Gene3D G3DSA:3.40.50.410 373 560 7.1E-29 T 28-03-2018 IPR002035 von Willebrand factor, type A CIG75_RS09580 ddc76a7064fd3a75d3e2737cddb4f935 562 Pfam PF00092 von Willebrand factor type A domain 391 542 3.2E-20 T 28-03-2018 IPR002035 von Willebrand factor, type A CIG75_RS09580 ddc76a7064fd3a75d3e2737cddb4f935 562 SUPERFAMILY SSF53850 108 353 2.17E-10 T 28-03-2018 CIG75_RS09580 ddc76a7064fd3a75d3e2737cddb4f935 562 SUPERFAMILY SSF53300 390 542 1.67E-26 T 28-03-2018 IPR002035 von Willebrand factor, type A CIG75_RS11960 4efe62a3b8d3dbee14ed1f855e236eef 410 Pfam PF00448 SRP54-type protein, GTPase domain 215 403 8.0E-41 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CIG75_RS11960 4efe62a3b8d3dbee14ed1f855e236eef 410 Gene3D G3DSA:3.40.50.300 212 406 9.7E-27 T 28-03-2018 CIG75_RS11960 4efe62a3b8d3dbee14ed1f855e236eef 410 SUPERFAMILY SSF52540 213 404 5.59E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS11960 4efe62a3b8d3dbee14ed1f855e236eef 410 TIGRFAM TIGR03499 FlhF: flagellar biosynthesis protein FlhF 1 301 2.2E-73 T 28-03-2018 IPR020006 Flagellar biosynthesis protein FlhF GO:0003924|GO:0044781 CIG75_RS11960 4efe62a3b8d3dbee14ed1f855e236eef 410 SMART SM00962 214 405 1.7E-55 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CIG75_RS11960 4efe62a3b8d3dbee14ed1f855e236eef 410 SMART SM00382 213 360 0.0015 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS09895 c0e425f94003d2a0ecdc7c18fa0c65da 285 SUPERFAMILY SSF51621 6 267 7.33E-109 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CIG75_RS09895 c0e425f94003d2a0ecdc7c18fa0c65da 285 PIRSF PIRSF000388 1 270 1.8E-114 T 28-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CIG75_RS09895 c0e425f94003d2a0ecdc7c18fa0c65da 285 Gene3D G3DSA:3.20.20.60 1 267 9.4E-86 T 28-03-2018 CIG75_RS09895 c0e425f94003d2a0ecdc7c18fa0c65da 285 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 5 268 2.0E-109 T 28-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CIG75_RS09895 c0e425f94003d2a0ecdc7c18fa0c65da 285 Pfam PF02548 Ketopantoate hydroxymethyltransferase 6 262 1.0E-115 T 28-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CIG75_RS09895 c0e425f94003d2a0ecdc7c18fa0c65da 285 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 6 267 44.323 T 28-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CIG75_RS11490 27c3e325bfbe1a5de4738f7574d92d8f 458 Gene3D G3DSA:3.30.1490.20 225 297 4.8E-12 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CIG75_RS11490 27c3e325bfbe1a5de4738f7574d92d8f 458 Gene3D G3DSA:3.30.470.20 298 433 3.6E-13 T 28-03-2018 CIG75_RS11490 27c3e325bfbe1a5de4738f7574d92d8f 458 Pfam PF14398 YheC/D like ATP-grasp 195 452 1.6E-73 T 28-03-2018 IPR026838 Endospore coat-associated protein YheC/D CIG75_RS11490 27c3e325bfbe1a5de4738f7574d92d8f 458 SUPERFAMILY SSF56059 218 423 9.3E-16 T 28-03-2018 CIG75_RS09815 8f59b7eb2b5b6b94f9226f7737d6e849 133 Pfam PF12680 SnoaL-like domain 30 128 1.0E-18 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CIG75_RS09815 8f59b7eb2b5b6b94f9226f7737d6e849 133 PIRSF PIRSF030561 21 133 7.2E-31 T 28-03-2018 IPR008317 Uncharacterised conserved protein UCP030561 CIG75_RS09815 8f59b7eb2b5b6b94f9226f7737d6e849 133 Gene3D G3DSA:3.10.450.50 2 133 7.6E-21 T 28-03-2018 CIG75_RS09815 8f59b7eb2b5b6b94f9226f7737d6e849 133 SUPERFAMILY SSF54427 29 132 2.66E-28 T 28-03-2018 IPR032710 NTF2-like domain CIG75_RS05495 095774c369f8aff8f7abbadaa7035fe8 229 Gene3D G3DSA:3.60.15.10 1 229 1.6E-39 T 28-03-2018 IPR001279 Metallo-beta-lactamase CIG75_RS05495 095774c369f8aff8f7abbadaa7035fe8 229 SUPERFAMILY SSF56281 1 211 2.36E-40 T 28-03-2018 IPR001279 Metallo-beta-lactamase CIG75_RS05495 095774c369f8aff8f7abbadaa7035fe8 229 Hamap MF_00457 UPF0173 metal-dependent hydrolase . 1 229 35.557 T 28-03-2018 IPR022877 Protein of unknown funcion UPF0173 CIG75_RS05495 095774c369f8aff8f7abbadaa7035fe8 229 SMART SM00849 7 193 1.7E-16 T 28-03-2018 IPR001279 Metallo-beta-lactamase CIG75_RS05495 095774c369f8aff8f7abbadaa7035fe8 229 Pfam PF13483 Beta-lactamase superfamily domain 2 193 3.9E-25 T 28-03-2018 CIG75_RS11705 27043333d9ea97314a2eb752eb16a507 263 Pfam PF00574 Clp protease 62 237 2.3E-33 T 28-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA CIG75_RS11705 27043333d9ea97314a2eb752eb16a507 263 SUPERFAMILY SSF52096 58 245 6.69E-37 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CIG75_RS11705 27043333d9ea97314a2eb752eb16a507 263 Gene3D G3DSA:3.90.226.10 63 263 2.0E-25 T 28-03-2018 CIG75_RS02850 08e98a5c92711c3987ce4624ba30f32c 412 Gene3D G3DSA:1.20.1250.20 12 214 6.5E-18 T 28-03-2018 CIG75_RS02850 08e98a5c92711c3987ce4624ba30f32c 412 Gene3D G3DSA:1.20.1250.20 215 408 2.3E-14 T 28-03-2018 CIG75_RS02850 08e98a5c92711c3987ce4624ba30f32c 412 Pfam PF05977 Transmembrane secretion effector 22 399 2.2E-38 T 28-03-2018 IPR010290 Transmembrane secretion effector CIG75_RS02850 08e98a5c92711c3987ce4624ba30f32c 412 SUPERFAMILY SSF103473 20 407 1.44E-42 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS05055 d57279af4d274f5c7d2250ee88572a8b 61 Gene3D G3DSA:2.60.300.12 1 61 3.3E-6 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CIG75_RS08915 0c424e5112861fc3c35c756c4185ff38 223 SMART SM00849 12 191 3.8E-42 T 28-03-2018 IPR001279 Metallo-beta-lactamase CIG75_RS08915 0c424e5112861fc3c35c756c4185ff38 223 Pfam PF00753 Metallo-beta-lactamase superfamily 11 191 2.9E-27 T 28-03-2018 IPR001279 Metallo-beta-lactamase CIG75_RS08915 0c424e5112861fc3c35c756c4185ff38 223 Gene3D G3DSA:3.60.15.10 1 214 2.8E-42 T 28-03-2018 IPR001279 Metallo-beta-lactamase CIG75_RS08915 0c424e5112861fc3c35c756c4185ff38 223 SUPERFAMILY SSF56281 8 204 3.25E-53 T 28-03-2018 IPR001279 Metallo-beta-lactamase CIG75_RS10130 f5f3f79827d68bd1bbb43f613144a1db 193 Pfam PF00574 Clp protease 13 192 8.1E-85 T 28-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA CIG75_RS10130 f5f3f79827d68bd1bbb43f613144a1db 193 SUPERFAMILY SSF52096 10 191 7.46E-73 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CIG75_RS10130 f5f3f79827d68bd1bbb43f613144a1db 193 PRINTS PR00127 Clp protease catalytic subunit P signature 90 107 3.2E-53 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CIG75_RS10130 f5f3f79827d68bd1bbb43f613144a1db 193 PRINTS PR00127 Clp protease catalytic subunit P signature 59 79 3.2E-53 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CIG75_RS10130 f5f3f79827d68bd1bbb43f613144a1db 193 PRINTS PR00127 Clp protease catalytic subunit P signature 19 34 3.2E-53 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CIG75_RS10130 f5f3f79827d68bd1bbb43f613144a1db 193 PRINTS PR00127 Clp protease catalytic subunit P signature 111 130 3.2E-53 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CIG75_RS10130 f5f3f79827d68bd1bbb43f613144a1db 193 PRINTS PR00127 Clp protease catalytic subunit P signature 168 187 3.2E-53 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CIG75_RS10130 f5f3f79827d68bd1bbb43f613144a1db 193 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 3 193 43.063 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CIG75_RS10130 f5f3f79827d68bd1bbb43f613144a1db 193 Gene3D G3DSA:3.90.226.10 2 193 3.6E-48 T 28-03-2018 CIG75_RS10130 f5f3f79827d68bd1bbb43f613144a1db 193 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 1 192 2.5E-97 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CIG75_RS10130 f5f3f79827d68bd1bbb43f613144a1db 193 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 112 125 - T 28-03-2018 IPR033135 ClpP, histidine active site CIG75_RS10130 f5f3f79827d68bd1bbb43f613144a1db 193 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 90 101 - T 28-03-2018 IPR018215 ClpP, Ser active site CIG75_RS06415 b66cc4d2650113eb916138df19ce57b9 149 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 1 145 2.0E-62 T 28-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 CIG75_RS06415 b66cc4d2650113eb916138df19ce57b9 149 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 2 144 3.3E-57 T 28-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 CIG75_RS06415 b66cc4d2650113eb916138df19ce57b9 149 Gene3D G3DSA:3.50.80.10 1 145 5.5E-59 T 28-03-2018 IPR023509 D-Tyr tRNAtyr deacylase-like domain CIG75_RS06415 b66cc4d2650113eb916138df19ce57b9 149 SUPERFAMILY SSF69500 1 144 3.14E-59 T 28-03-2018 IPR023509 D-Tyr tRNAtyr deacylase-like domain CIG75_RS06415 b66cc4d2650113eb916138df19ce57b9 149 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 145 36.371 T 28-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 CIG75_RS11315 dbc88ae674ec918c0d5228854efc41d5 286 Gene3D G3DSA:3.60.21.10 10 286 4.8E-23 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CIG75_RS11315 dbc88ae674ec918c0d5228854efc41d5 286 TIGRFAM TIGR03729 acc_ester: putative phosphoesterase 13 264 4.9E-51 T 28-03-2018 IPR022302 Phosphoesterase, putative CIG75_RS11315 dbc88ae674ec918c0d5228854efc41d5 286 SUPERFAMILY SSF56300 12 134 1.39E-22 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CIG75_RS11315 dbc88ae674ec918c0d5228854efc41d5 286 SUPERFAMILY SSF56300 169 267 1.39E-22 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CIG75_RS11315 dbc88ae674ec918c0d5228854efc41d5 286 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 13 261 5.7E-10 T 28-03-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 CIG75_RS04670 fe81c243d39b20f5ee4c77454e7d0af1 315 SUPERFAMILY SSF51197 7 309 1.65E-73 T 28-03-2018 CIG75_RS04670 fe81c243d39b20f5ee4c77454e7d0af1 315 Gene3D G3DSA:2.60.120.330 2 313 6.4E-79 T 28-03-2018 IPR027443 Isopenicillin N synthase-like CIG75_RS04670 fe81c243d39b20f5ee4c77454e7d0af1 315 Pfam PF03171 2OG-Fe(II) oxygenase superfamily 170 273 2.7E-14 T 28-03-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 CIG75_RS04670 fe81c243d39b20f5ee4c77454e7d0af1 315 PRINTS PR00682 Isopenicillin N synthase signature 28 45 2.8E-7 T 28-03-2018 CIG75_RS04670 fe81c243d39b20f5ee4c77454e7d0af1 315 PRINTS PR00682 Isopenicillin N synthase signature 195 216 2.8E-7 T 28-03-2018 CIG75_RS04670 fe81c243d39b20f5ee4c77454e7d0af1 315 PRINTS PR00682 Isopenicillin N synthase signature 231 257 2.8E-7 T 28-03-2018 CIG75_RS04670 fe81c243d39b20f5ee4c77454e7d0af1 315 Pfam PF14226 non-haem dioxygenase in morphine synthesis N-terminal 10 124 5.5E-21 T 28-03-2018 IPR026992 Non-haem dioxygenase N-terminal domain CIG75_RS08585 75f1f4410d2ae84c128575ffc83148d0 71 Pfam PF07561 Domain of Unknown Function (DUF1540) 5 46 2.0E-10 T 28-03-2018 IPR011437 Domain of unknown function DUF1540 CIG75_RS06890 f6883199d495e39374ec08267be81234 443 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 9 138 1.6E-17 T 28-03-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 CIG75_RS06890 f6883199d495e39374ec08267be81234 443 Gene3D G3DSA:3.40.50.300 3 156 1.4E-30 T 28-03-2018 CIG75_RS06890 f6883199d495e39374ec08267be81234 443 Gene3D G3DSA:1.20.272.10 255 349 9.2E-42 T 28-03-2018 CIG75_RS06890 f6883199d495e39374ec08267be81234 443 SUPERFAMILY SSF48019 256 437 3.46E-80 T 28-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CIG75_RS06890 f6883199d495e39374ec08267be81234 443 Pfam PF16193 AAA C-terminal domain 192 270 1.6E-27 T 28-03-2018 IPR032423 AAA C-terminal domain CIG75_RS06890 f6883199d495e39374ec08267be81234 443 Gene3D G3DSA:1.10.3710.10 352 443 1.5E-32 T 28-03-2018 CIG75_RS06890 f6883199d495e39374ec08267be81234 443 Pfam PF12002 MgsA AAA+ ATPase C terminal 271 436 1.7E-75 T 28-03-2018 IPR021886 MgsA AAA+ ATPase C-terminal CIG75_RS06890 f6883199d495e39374ec08267be81234 443 SMART SM00382 51 168 1.4E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS06890 f6883199d495e39374ec08267be81234 443 SUPERFAMILY SSF52540 13 237 1.27E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS06890 f6883199d495e39374ec08267be81234 443 Gene3D G3DSA:1.10.8.60 157 246 1.1E-20 T 28-03-2018 CIG75_RS03830 0577bcac4885fe2deebb58b18c36f581 481 Pfam PF01425 Amidase 24 463 5.0E-161 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CIG75_RS03830 0577bcac4885fe2deebb58b18c36f581 481 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 11 474 93.298 T 28-03-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CIG75_RS03830 0577bcac4885fe2deebb58b18c36f581 481 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 12 472 3.0E-193 T 28-03-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CIG75_RS03830 0577bcac4885fe2deebb58b18c36f581 481 Gene3D G3DSA:3.90.1300.10 1 481 1.9E-171 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CIG75_RS03830 0577bcac4885fe2deebb58b18c36f581 481 SUPERFAMILY SSF75304 2 473 4.84E-164 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CIG75_RS03310 110e3809f5550a5af309341ac160c46e 203 Gene3D G3DSA:1.10.10.60 5 58 1.5E-17 T 28-03-2018 CIG75_RS03310 110e3809f5550a5af309341ac160c46e 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 10 23 4.6E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CIG75_RS03310 110e3809f5550a5af309341ac160c46e 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 54 4.6E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CIG75_RS03310 110e3809f5550a5af309341ac160c46e 203 SUPERFAMILY SSF48498 77 191 2.64E-12 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CIG75_RS03310 110e3809f5550a5af309341ac160c46e 203 SUPERFAMILY SSF46689 3 81 1.5E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CIG75_RS03310 110e3809f5550a5af309341ac160c46e 203 Gene3D G3DSA:1.10.357.10 59 192 3.0E-18 T 28-03-2018 CIG75_RS03310 110e3809f5550a5af309341ac160c46e 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 56 1.0E-15 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CIG75_RS02995 1bcf43b59daed3af507047c1fcb1d956 548 Gene3D G3DSA:1.10.3720.10 15 274 1.4E-26 T 28-03-2018 CIG75_RS02995 1bcf43b59daed3af507047c1fcb1d956 548 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 76 260 2.0E-9 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CIG75_RS02995 1bcf43b59daed3af507047c1fcb1d956 548 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 349 545 4.1E-8 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CIG75_RS02995 1bcf43b59daed3af507047c1fcb1d956 548 Gene3D G3DSA:1.10.3720.10 320 548 8.9E-24 T 28-03-2018 CIG75_RS02995 1bcf43b59daed3af507047c1fcb1d956 548 SUPERFAMILY SSF161098 16 266 6.21E-40 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CIG75_RS02995 1bcf43b59daed3af507047c1fcb1d956 548 SUPERFAMILY SSF161098 287 540 2.83E-34 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CIG75_RS09440 1bc76832c6b4456f5ff2e8799150e297 290 Pfam PF06267 Family of unknown function (DUF1028) 9 203 3.3E-77 T 28-03-2018 IPR010430 Protein of unknown function DUF1028 CIG75_RS09440 1bc76832c6b4456f5ff2e8799150e297 290 SUPERFAMILY SSF56235 9 227 2.08E-72 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CIG75_RS09440 1bc76832c6b4456f5ff2e8799150e297 290 Gene3D G3DSA:3.60.20.10 6 227 2.6E-81 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CIG75_RS09440 1bc76832c6b4456f5ff2e8799150e297 290 Pfam PF08823 Putative peptidoglycan binding domain 215 287 3.4E-10 T 28-03-2018 IPR014927 Putative peptidoglycan binding CIG75_RS17635 1bfbd306599c83b787a9a445f40222a2 320 Gene3D G3DSA:3.20.20.150 65 319 1.4E-24 T 28-03-2018 CIG75_RS17635 1bfbd306599c83b787a9a445f40222a2 320 Pfam PF05114 Protein of unknown function (DUF692) 94 287 1.7E-15 T 28-03-2018 IPR007801 Uncharacterised protein family UPF0276 CIG75_RS00465 96bf84542303b741bdb433d6dca20514 122 Gene3D G3DSA:3.90.1150.10 15 121 1.9E-18 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CIG75_RS00465 96bf84542303b741bdb433d6dca20514 122 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 52 120 6.4E-12 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CIG75_RS00465 96bf84542303b741bdb433d6dca20514 122 SUPERFAMILY SSF53383 11 120 1.3E-20 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CIG75_RS17235 a1469fe7c173ec29dcf97233952c0164 360 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 205 356 7.2E-20 T 28-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 CIG75_RS17235 a1469fe7c173ec29dcf97233952c0164 360 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 14 358 4.3E-51 T 28-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 CIG75_RS08260 b2504e3505f92f1433a8320ce885016c 450 Gene3D G3DSA:3.90.1150.10 338 450 4.3E-29 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CIG75_RS08260 b2504e3505f92f1433a8320ce885016c 450 Hamap MF_00712 Probable glycine dehydrogenase (decarboxylating) subunit 1 [gcvPA]. 4 449 49.911 T 28-03-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 CIG75_RS08260 b2504e3505f92f1433a8320ce885016c 450 Gene3D G3DSA:3.40.640.10 85 337 5.5E-39 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CIG75_RS08260 b2504e3505f92f1433a8320ce885016c 450 Pfam PF02347 Glycine cleavage system P-protein 5 443 3.1E-140 T 28-03-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 CIG75_RS08260 b2504e3505f92f1433a8320ce885016c 450 PIRSF PIRSF006815 4 450 6.6E-195 T 28-03-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 CIG75_RS08260 b2504e3505f92f1433a8320ce885016c 450 SUPERFAMILY SSF53383 5 450 7.83E-119 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CIG75_RS12105 5ee298cae72ff48d25df3a78baf31995 437 Hamap MF_01037 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO [trmFO]. 5 434 36.302 T 28-03-2018 IPR004417 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO GO:0005737|GO:0008033|GO:0047151|GO:0050660 CIG75_RS12105 5ee298cae72ff48d25df3a78baf31995 437 Gene3D G3DSA:3.50.50.60 1 371 9.9E-19 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS12105 5ee298cae72ff48d25df3a78baf31995 437 SUPERFAMILY SSF51905 2 367 5.83E-26 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS12105 5ee298cae72ff48d25df3a78baf31995 437 Pfam PF01134 Glucose inhibited division protein A 5 367 9.2E-114 T 28-03-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 CIG75_RS12105 5ee298cae72ff48d25df3a78baf31995 437 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 337 360 - T 28-03-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 CIG75_RS12105 5ee298cae72ff48d25df3a78baf31995 437 TIGRFAM TIGR00137 gid_trmFO: tRNA:m(5)U-54 methyltransferase 3 433 2.2E-223 T 28-03-2018 IPR004417 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO GO:0005737|GO:0008033|GO:0047151|GO:0050660 CIG75_RS19685 893cf7496395e68401a4c691910874d5 122 Gene3D G3DSA:2.40.150.20 1 122 1.8E-52 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CIG75_RS19685 893cf7496395e68401a4c691910874d5 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 27.592 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CIG75_RS19685 893cf7496395e68401a4c691910874d5 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 8.2E-58 T 28-03-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 CIG75_RS19685 893cf7496395e68401a4c691910874d5 122 SMART SM01374 1 122 9.1E-86 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CIG75_RS19685 893cf7496395e68401a4c691910874d5 122 SUPERFAMILY SSF50193 1 122 4.45E-51 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CIG75_RS19685 893cf7496395e68401a4c691910874d5 122 Pfam PF00238 Ribosomal protein L14p/L23e 1 122 3.1E-54 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CIG75_RS19685 893cf7496395e68401a4c691910874d5 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 28-03-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CIG75_RS14910 2ae208eeaabc2a59ffad8f85cc1709b3 322 Gene3D G3DSA:3.20.20.150 41 307 3.0E-22 T 28-03-2018 CIG75_RS14910 2ae208eeaabc2a59ffad8f85cc1709b3 322 SUPERFAMILY SSF51658 80 288 5.47E-16 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CIG75_RS14910 2ae208eeaabc2a59ffad8f85cc1709b3 322 Pfam PF03851 UV-endonuclease UvdE 5 274 1.9E-87 T 28-03-2018 IPR004601 UV-endonuclease UvdE GO:0004519|GO:0006289|GO:0009411 CIG75_RS14910 2ae208eeaabc2a59ffad8f85cc1709b3 322 TIGRFAM TIGR00629 uvde: UV damage endonuclease UvdE 1 305 2.9E-81 T 28-03-2018 IPR004601 UV-endonuclease UvdE GO:0004519|GO:0006289|GO:0009411 CIG75_RS14170 20fc494d423fee93e64c7ec0441c616a 730 Gene3D G3DSA:2.60.40.10 232 323 8.4E-4 T 28-03-2018 IPR013783 Immunoglobulin-like fold CIG75_RS14170 20fc494d423fee93e64c7ec0441c616a 730 Gene3D G3DSA:2.60.40.10 130 231 0.13 T 28-03-2018 IPR013783 Immunoglobulin-like fold CIG75_RS14170 20fc494d423fee93e64c7ec0441c616a 730 Gene3D G3DSA:2.60.40.10 38 129 7.6E-6 T 28-03-2018 IPR013783 Immunoglobulin-like fold CIG75_RS14170 20fc494d423fee93e64c7ec0441c616a 730 Pfam PF00395 S-layer homology domain 542 584 3.8E-12 T 28-03-2018 IPR001119 S-layer homology domain CIG75_RS14170 20fc494d423fee93e64c7ec0441c616a 730 Pfam PF00395 S-layer homology domain 603 645 5.9E-7 T 28-03-2018 IPR001119 S-layer homology domain CIG75_RS11690 e63d9e7dc1e7c50d414bea57177deca1 231 Pfam PF07702 UTRA domain 85 220 5.0E-27 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CIG75_RS11690 e63d9e7dc1e7c50d414bea57177deca1 231 SMART SM00345 3 62 5.9E-23 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CIG75_RS11690 e63d9e7dc1e7c50d414bea57177deca1 231 SUPERFAMILY SSF46785 2 76 5.67E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS11690 e63d9e7dc1e7c50d414bea57177deca1 231 Pfam PF00392 Bacterial regulatory proteins, gntR family 3 62 3.5E-20 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CIG75_RS11690 e63d9e7dc1e7c50d414bea57177deca1 231 SUPERFAMILY SSF64288 50 228 3.14E-37 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CIG75_RS11690 e63d9e7dc1e7c50d414bea57177deca1 231 Gene3D G3DSA:3.40.1410.10 63 229 7.7E-29 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CIG75_RS11690 e63d9e7dc1e7c50d414bea57177deca1 231 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 22 36 7.0E-11 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CIG75_RS11690 e63d9e7dc1e7c50d414bea57177deca1 231 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 36 52 7.0E-11 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CIG75_RS11690 e63d9e7dc1e7c50d414bea57177deca1 231 Gene3D G3DSA:1.10.10.10 1 62 3.9E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS11690 e63d9e7dc1e7c50d414bea57177deca1 231 SMART SM00866 84 221 3.2E-22 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CIG75_RS09720 3781b9a527def022ba10d3d313310aa8 620 Gene3D G3DSA:3.20.20.370 246 535 2.5E-8 T 28-03-2018 CIG75_RS09720 3781b9a527def022ba10d3d313310aa8 620 Pfam PF09960 Uncharacterised protein conserved in bacteria (DUF2194) 214 571 1.0E-76 T 28-03-2018 IPR018695 Protein of unknown function DUF2194 CIG75_RS09720 3781b9a527def022ba10d3d313310aa8 620 Gene3D G3DSA:3.40.50.880 60 245 4.9E-4 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CIG75_RS18540 8eabbc255b670ed7de03b4bc5ff2eebc 338 SUPERFAMILY SSF53474 211 333 1.47E-42 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS18540 8eabbc255b670ed7de03b4bc5ff2eebc 338 SUPERFAMILY SSF53474 28 167 1.47E-42 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS18540 8eabbc255b670ed7de03b4bc5ff2eebc 338 Pfam PF12146 Serine aminopeptidase, S33 75 295 8.1E-16 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 CIG75_RS18540 8eabbc255b670ed7de03b4bc5ff2eebc 338 Gene3D G3DSA:3.40.50.1820 10 338 7.9E-37 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS17005 98a2b9883dfd4c260cee6d46c04f3d1f 97 Gene3D G3DSA:3.90.1720.10 1 69 3.1E-6 T 28-03-2018 CIG75_RS06000 f2ef678aef50fb0b51053a74e89d664d 217 Gene3D G3DSA:3.30.70.1450 136 217 3.5E-20 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CIG75_RS06000 f2ef678aef50fb0b51053a74e89d664d 217 Pfam PF02254 TrkA-N domain 5 120 3.1E-29 T 28-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 CIG75_RS06000 f2ef678aef50fb0b51053a74e89d664d 217 SUPERFAMILY SSF51735 3 136 1.74E-38 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS06000 f2ef678aef50fb0b51053a74e89d664d 217 SUPERFAMILY SSF116726 131 213 1.83E-21 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CIG75_RS06000 f2ef678aef50fb0b51053a74e89d664d 217 Pfam PF02080 TrkA-C domain 150 213 8.1E-15 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CIG75_RS06000 f2ef678aef50fb0b51053a74e89d664d 217 Gene3D G3DSA:3.40.50.720 3 135 1.1E-24 T 28-03-2018 CIG75_RS08165 5cdf16b257ab960eb7be0df933d658c9 350 Gene3D G3DSA:3.30.450.90 3 114 2.3E-32 T 28-03-2018 CIG75_RS08165 5cdf16b257ab960eb7be0df933d658c9 350 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 208 222 - T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CIG75_RS08165 5cdf16b257ab960eb7be0df933d658c9 350 SUPERFAMILY SSF52540 4 343 5.1E-66 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS08165 5cdf16b257ab960eb7be0df933d658c9 350 Gene3D G3DSA:3.40.50.300 115 280 1.2E-31 T 28-03-2018 CIG75_RS08165 5cdf16b257ab960eb7be0df933d658c9 350 Gene3D G3DSA:3.40.50.300 281 348 0.016 T 28-03-2018 CIG75_RS08165 5cdf16b257ab960eb7be0df933d658c9 350 Pfam PF00437 Type II/IV secretion system protein 21 279 9.8E-67 T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CIG75_RS17855 35727b339b38ad6441a075b752cae665 197 Gene3D G3DSA:2.60.120.380 72 193 2.4E-10 T 28-03-2018 CIG75_RS07520 c1c046d378a6ea61f96dfd3616e8b0aa 305 SUPERFAMILY SSF48317 193 284 1.96E-12 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CIG75_RS07520 c1c046d378a6ea61f96dfd3616e8b0aa 305 SUPERFAMILY SSF48317 53 163 1.96E-12 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CIG75_RS07520 c1c046d378a6ea61f96dfd3616e8b0aa 305 Gene3D G3DSA:1.20.144.10 3 271 4.5E-10 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CIG75_RS07520 c1c046d378a6ea61f96dfd3616e8b0aa 305 Pfam PF01569 PAP2 superfamily 196 271 1.1E-13 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CIG75_RS10435 7acacfb0f71562f5eaa23e7a47decf63 508 Pfam PF00221 Aromatic amino acid lyase 12 468 2.3E-202 T 28-03-2018 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 CIG75_RS10435 7acacfb0f71562f5eaa23e7a47decf63 508 Gene3D G3DSA:1.10.275.10 2 197 1.7E-79 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal CIG75_RS10435 7acacfb0f71562f5eaa23e7a47decf63 508 Gene3D G3DSA:1.20.200.10 199 506 7.7E-129 T 28-03-2018 CIG75_RS10435 7acacfb0f71562f5eaa23e7a47decf63 508 SUPERFAMILY SSF48557 3 500 5.73E-197 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 CIG75_RS10435 7acacfb0f71562f5eaa23e7a47decf63 508 TIGRFAM TIGR01225 hutH: histidine ammonia-lyase 4 502 7.9E-216 T 28-03-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CIG75_RS10435 7acacfb0f71562f5eaa23e7a47decf63 508 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 139 155 - T 28-03-2018 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 Reactome: R-HSA-70921 CIG75_RS10435 7acacfb0f71562f5eaa23e7a47decf63 508 Hamap MF_00229 Histidine ammonia-lyase [hutH]. 3 502 45.681 T 28-03-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CIG75_RS07635 1c49d910a736bb317c2cf1de63960b2f 52 Pfam PF03597 Cytochrome oxidase maturation protein cbb3-type 8 46 4.7E-10 T 28-03-2018 IPR004714 Cytochrome oxidase maturation protein cbb3-type CIG75_RS07635 1c49d910a736bb317c2cf1de63960b2f 52 TIGRFAM TIGR00847 ccoS: cytochrome oxidase maturation protein, cbb3-type 8 46 3.6E-9 T 28-03-2018 IPR004714 Cytochrome oxidase maturation protein cbb3-type CIG75_RS00795 6a8bf085bf893672bfe7f9ffd31f9f13 152 Pfam PF07690 Major Facilitator Superfamily 3 143 8.1E-9 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CIG75_RS00795 6a8bf085bf893672bfe7f9ffd31f9f13 152 SUPERFAMILY SSF103473 3 146 4.58E-15 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS00795 6a8bf085bf893672bfe7f9ffd31f9f13 152 Gene3D G3DSA:1.20.1250.20 1 151 6.5E-12 T 28-03-2018 CIG75_RS13965 0b1a4a7d31992fd5166d3ca7093966a1 256 Gene3D G3DSA:3.40.50.1000 2 247 1.1E-21 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS13965 0b1a4a7d31992fd5166d3ca7093966a1 256 SUPERFAMILY SSF56784 2 232 2.8E-26 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS13965 0b1a4a7d31992fd5166d3ca7093966a1 256 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 202 2.2E-12 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS02730 d323ca5b376116decdfa112a0e44b79d 186 Pfam PF08006 Protein of unknown function (DUF1700) 1 180 3.3E-55 T 28-03-2018 IPR012963 Protein of unknown function DUF1700 CIG75_RS03995 81ee5a54b91fa26a2d24695808a8697a 235 Pfam PF03781 Sulfatase-modifying factor enzyme 1 58 233 4.3E-36 T 28-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 CIG75_RS03995 81ee5a54b91fa26a2d24695808a8697a 235 SUPERFAMILY SSF56436 33 94 8.01E-49 T 28-03-2018 IPR016187 C-type lectin fold CIG75_RS03995 81ee5a54b91fa26a2d24695808a8697a 235 SUPERFAMILY SSF56436 121 234 8.01E-49 T 28-03-2018 IPR016187 C-type lectin fold CIG75_RS03995 81ee5a54b91fa26a2d24695808a8697a 235 Gene3D G3DSA:3.90.1580.10 39 230 1.7E-46 T 28-03-2018 CIG75_RS05590 0798ec8be30a1058e6c2917a094cb094 309 Gene3D G3DSA:1.10.3720.10 2 292 5.5E-42 T 28-03-2018 CIG75_RS05590 0798ec8be30a1058e6c2917a094cb094 309 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 303 1.3E-38 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CIG75_RS05590 0798ec8be30a1058e6c2917a094cb094 309 SUPERFAMILY SSF161098 89 286 8.5E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CIG75_RS11765 d7762f9c21af81385113d58ea75b16d1 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 10 88 3.0E-31 T 28-03-2018 CIG75_RS11765 d7762f9c21af81385113d58ea75b16d1 89 Gene3D G3DSA:1.10.287.10 2 89 1.1E-36 T 28-03-2018 CIG75_RS11765 d7762f9c21af81385113d58ea75b16d1 89 SUPERFAMILY SSF47060 3 89 1.71E-36 T 28-03-2018 IPR009068 S15/NS1, RNA-binding CIG75_RS11765 d7762f9c21af81385113d58ea75b16d1 89 SMART SM01387 8 88 1.2E-51 T 28-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS11765 d7762f9c21af81385113d58ea75b16d1 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 28-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS11765 d7762f9c21af81385113d58ea75b16d1 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 22.453 T 28-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS11765 d7762f9c21af81385113d58ea75b16d1 89 Pfam PF00312 Ribosomal protein S15 8 88 9.2E-38 T 28-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS11765 d7762f9c21af81385113d58ea75b16d1 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 5 89 7.3E-40 T 28-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS16660 c217fe758cb78d76c44c10b90d1fb995 481 Pfam PF14344 Domain of unknown function (DUF4397) 290 404 1.1E-30 T 28-03-2018 IPR025510 Domain of unknown function DUF4397 CIG75_RS20300 b5cbfc9ba24ffe425dd874bf6cd18f9a 95 Gene3D G3DSA:3.30.1120.40 1 83 5.1E-37 T 28-03-2018 IPR007170 Stage V sporulation protein G GO:0030435 CIG75_RS20300 b5cbfc9ba24ffe425dd874bf6cd18f9a 95 Pfam PF04026 SpoVG 2 81 5.0E-37 T 28-03-2018 IPR007170 Stage V sporulation protein G GO:0030435 CIG75_RS20300 b5cbfc9ba24ffe425dd874bf6cd18f9a 95 SUPERFAMILY SSF160537 2 84 2.62E-33 T 28-03-2018 IPR007170 Stage V sporulation protein G GO:0030435 CIG75_RS20300 b5cbfc9ba24ffe425dd874bf6cd18f9a 95 Hamap MF_00819 Putative septation protein SpoVG [spoVG]. 1 92 28.49 T 28-03-2018 IPR007170 Stage V sporulation protein G GO:0030435 CIG75_RS04750 6daed75f09a179c89348759f85acf9bf 438 Pfam PF16491 CAAX prenyl protease N-terminal, five membrane helices 53 218 1.0E-23 T 28-03-2018 IPR032456 CAAX prenyl protease 1, N-terminal KEGG: 00900+3.4.24.84 CIG75_RS04750 6daed75f09a179c89348759f85acf9bf 438 Pfam PF01435 Peptidase family M48 222 431 1.6E-33 T 28-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 CIG75_RS04750 6daed75f09a179c89348759f85acf9bf 438 Gene3D G3DSA:3.30.2010.10 218 300 2.5E-18 T 28-03-2018 CIG75_RS18140 d055f9979298a9ac17c4e271e0186427 408 SMART SM00028 219 252 22.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS18140 d055f9979298a9ac17c4e271e0186427 408 SMART SM00028 298 331 290.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS18140 d055f9979298a9ac17c4e271e0186427 408 SMART SM00028 259 292 60.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS18140 d055f9979298a9ac17c4e271e0186427 408 SMART SM00028 139 172 66.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS18140 d055f9979298a9ac17c4e271e0186427 408 Gene3D G3DSA:1.25.40.10 49 244 1.4E-20 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS18140 d055f9979298a9ac17c4e271e0186427 408 Gene3D G3DSA:1.25.40.10 324 383 0.03 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS18140 d055f9979298a9ac17c4e271e0186427 408 Pfam PF01381 Helix-turn-helix 1 45 7.8E-6 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS18140 d055f9979298a9ac17c4e271e0186427 408 Gene3D G3DSA:1.10.260.40 1 48 7.9E-8 T 28-03-2018 CIG75_RS18140 d055f9979298a9ac17c4e271e0186427 408 SUPERFAMILY SSF48452 219 246 1.9E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS18140 d055f9979298a9ac17c4e271e0186427 408 SUPERFAMILY SSF48452 98 172 1.9E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS18140 d055f9979298a9ac17c4e271e0186427 408 SUPERFAMILY SSF47413 2 51 8.0E-7 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CIG75_RS18140 d055f9979298a9ac17c4e271e0186427 408 SUPERFAMILY SSF48452 197 374 3.57E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS18140 d055f9979298a9ac17c4e271e0186427 408 Gene3D G3DSA:1.25.40.10 245 323 2.0E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS20275 179cbdc7cccb9f8c215b0fe06afd74b7 77 ProDom PD057826 YABK 5 77 5.0E-11 T 28-03-2018 IPR020115 Anti-sigma-F factor Fin GO:0010468 CIG75_RS20275 179cbdc7cccb9f8c215b0fe06afd74b7 77 Pfam PF10955 Protein of unknown function (DUF2757) 2 70 3.4E-22 T 28-03-2018 IPR020115 Anti-sigma-F factor Fin GO:0010468 CIG75_RS05785 3fc977a96e0ca21d9a26d92c509007cb 398 Gene3D G3DSA:1.20.1090.10 193 398 7.7E-43 T 28-03-2018 CIG75_RS05785 3fc977a96e0ca21d9a26d92c509007cb 398 Pfam PF00465 Iron-containing alcohol dehydrogenase 9 371 5.6E-103 T 28-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 CIG75_RS05785 3fc977a96e0ca21d9a26d92c509007cb 398 SUPERFAMILY SSF56796 3 396 5.76E-104 T 28-03-2018 CIG75_RS05785 3fc977a96e0ca21d9a26d92c509007cb 398 Gene3D G3DSA:3.40.50.1970 9 191 5.6E-49 T 28-03-2018 CIG75_RS17010 cbea90535b5511f7405a3eed93a6c77a 206 Pfam PF14301 Domain of unknown function (DUF4376) 99 200 7.8E-8 T 28-03-2018 IPR025484 Domain of unknown function DUF4376 CIG75_RS18815 390ddef3685ef73c6887f6a80e27f8a8 167 Pfam PF04229 GrpB protein 17 158 2.9E-19 T 28-03-2018 IPR007344 GrpB/Dephospho-CoA kinase CIG75_RS18815 390ddef3685ef73c6887f6a80e27f8a8 167 Gene3D G3DSA:3.30.460.10 7 164 3.4E-22 T 28-03-2018 CIG75_RS18815 390ddef3685ef73c6887f6a80e27f8a8 167 SUPERFAMILY SSF81301 17 158 4.09E-25 T 28-03-2018 CIG75_RS12190 5ac40f2cc39d5fb548f429f37a275c9e 77 Pfam PF03672 Uncharacterised protein family (UPF0154) 9 65 1.5E-12 T 28-03-2018 IPR005359 Protein with unknown function UPF0154 CIG75_RS04275 43b424fbfb6d0c342eb0e54db53baaf1 53 Gene3D G3DSA:1.10.1220.10 4 44 2.2E-17 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CIG75_RS04275 43b424fbfb6d0c342eb0e54db53baaf1 53 Pfam PF03869 Arc-like DNA binding domain 1 49 1.0E-5 T 28-03-2018 IPR005569 Arc-like DNA binding domain GO:0003677 CIG75_RS04275 43b424fbfb6d0c342eb0e54db53baaf1 53 SUPERFAMILY SSF47598 2 49 1.38E-12 T 28-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 CIG75_RS11220 03bb39d70d010f1143bc25988ded0fe3 370 Gene3D G3DSA:2.30.300.10 31 199 4.7E-9 T 28-03-2018 CIG75_RS11220 03bb39d70d010f1143bc25988ded0fe3 370 Pfam PF05954 Phage late control gene D protein (GPD) 60 355 7.2E-9 T 28-03-2018 CIG75_RS11220 03bb39d70d010f1143bc25988ded0fe3 370 SUPERFAMILY SSF69279 27 200 1.02E-18 T 28-03-2018 CIG75_RS15585 988a103f43a442aa0623fa12931c66d8 98 Pfam PF13273 Protein of unknown function (DUF4064) 15 66 7.0E-9 T 28-03-2018 IPR025273 Domain of unknown function DUF4064 CIG75_RS02035 6113a066365a2879cedd2f2be154e802 326 Pfam PF01551 Peptidase family M23 152 250 2.1E-25 T 28-03-2018 IPR016047 Peptidase M23 CIG75_RS02035 6113a066365a2879cedd2f2be154e802 326 Gene3D G3DSA:2.70.70.10 17 257 2.6E-31 T 28-03-2018 CIG75_RS02035 6113a066365a2879cedd2f2be154e802 326 SUPERFAMILY SSF51261 149 254 5.75E-27 T 28-03-2018 IPR011055 Duplicated hybrid motif CIG75_RS02905 d8144b57811e91970881fffbe3c8fe4d 280 Pfam PF04454 Encapsulating protein for peroxidase 9 265 3.4E-70 T 28-03-2018 IPR007544 Encapsulating protein for peroxidase GO:0008233|GO:0042742 CIG75_RS09845 7f156f94b70bb09d5b86b131a20ac6fb 70 Gene3D G3DSA:3.30.70.100 1 69 7.4E-13 T 28-03-2018 CIG75_RS09845 7f156f94b70bb09d5b86b131a20ac6fb 70 Pfam PF00403 Heavy-metal-associated domain 18 65 8.6E-6 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CIG75_RS09845 7f156f94b70bb09d5b86b131a20ac6fb 70 SUPERFAMILY SSF55008 3 68 3.4E-13 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CIG75_RS11395 e33748d82ff5cf9bb4517ae500bc326f 282 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 217 271 4.4E-21 T 28-03-2018 IPR019264 Domain of unknown function DUF2179 CIG75_RS11395 e33748d82ff5cf9bb4517ae500bc326f 282 PIRSF PIRSF006483 1 278 1.1E-89 T 28-03-2018 IPR003740 Uncharacterised membrane protein YitT CIG75_RS11395 e33748d82ff5cf9bb4517ae500bc326f 282 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 9 211 1.0E-64 T 28-03-2018 IPR003740 Uncharacterised membrane protein YitT CIG75_RS08625 d3753d9e7f8d368e2280385c8f87c8b5 67 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 5 67 5.6E-18 T 28-03-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 CIG75_RS08625 d3753d9e7f8d368e2280385c8f87c8b5 67 ProSitePatterns PS01047 Heavy-metal-associated domain. 8 36 - T 28-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 CIG75_RS08625 d3753d9e7f8d368e2280385c8f87c8b5 67 Pfam PF00403 Heavy-metal-associated domain 5 65 1.0E-17 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CIG75_RS08625 d3753d9e7f8d368e2280385c8f87c8b5 67 Gene3D G3DSA:3.30.70.100 1 67 1.1E-21 T 28-03-2018 CIG75_RS08625 d3753d9e7f8d368e2280385c8f87c8b5 67 SUPERFAMILY SSF55008 2 66 1.44E-18 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CIG75_RS00640 02bb26cfe7ad482a8e4c438a0b93b86f 159 Pfam PF11188 Protein of unknown function (DUF2975) 31 159 3.2E-34 T 28-03-2018 IPR021354 Protein of unknown function DUF2975 CIG75_RS04870 d257de4caa89162c954b1c84da38c073 258 Gene3D G3DSA:1.10.1670.10 154 248 3.6E-19 T 28-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CIG75_RS17555 b017eb65cd39aebbaca7f186142bf64e 576 SUPERFAMILY SSF82171 15 53 5.23E-11 T 28-03-2018 CIG75_RS17555 b017eb65cd39aebbaca7f186142bf64e 576 SUPERFAMILY SSF82171 88 321 5.23E-11 T 28-03-2018 CIG75_RS17555 b017eb65cd39aebbaca7f186142bf64e 576 Gene3D G3DSA:3.40.50.1820 320 576 1.0E-35 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS17555 b017eb65cd39aebbaca7f186142bf64e 576 Pfam PF00326 Prolyl oligopeptidase family 376 570 9.5E-14 T 28-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 CIG75_RS17555 b017eb65cd39aebbaca7f186142bf64e 576 Gene3D G3DSA:2.140.10.30 8 319 5.7E-14 T 28-03-2018 CIG75_RS17555 b017eb65cd39aebbaca7f186142bf64e 576 SUPERFAMILY SSF53474 289 570 9.7E-38 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS09060 7d71e037df404659740995c948f75915 411 SUPERFAMILY SSF103473 15 409 1.01E-55 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS09060 7d71e037df404659740995c948f75915 411 Pfam PF07690 Major Facilitator Superfamily 21 250 2.0E-26 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CIG75_RS09060 7d71e037df404659740995c948f75915 411 PRINTS PR01035 Tetracycline resistance protein signature 353 376 1.9E-9 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CIG75_RS09060 7d71e037df404659740995c948f75915 411 PRINTS PR01035 Tetracycline resistance protein signature 27 43 1.9E-9 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CIG75_RS09060 7d71e037df404659740995c948f75915 411 PRINTS PR01035 Tetracycline resistance protein signature 142 164 1.9E-9 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CIG75_RS09060 7d71e037df404659740995c948f75915 411 PRINTS PR01035 Tetracycline resistance protein signature 170 190 1.9E-9 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CIG75_RS09060 7d71e037df404659740995c948f75915 411 Gene3D G3DSA:1.20.1250.20 14 207 6.2E-26 T 28-03-2018 CIG75_RS09060 7d71e037df404659740995c948f75915 411 Gene3D G3DSA:1.20.1250.20 219 411 1.4E-23 T 28-03-2018 CIG75_RS04615 c2a99ae612e220565fae4541c26c3575 505 Pfam PF02074 Carboxypeptidase Taq (M32) metallopeptidase 5 499 8.4E-155 T 28-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CIG75_RS04615 c2a99ae612e220565fae4541c26c3575 505 SUPERFAMILY SSF55486 11 499 2.86E-109 T 28-03-2018 CIG75_RS04615 c2a99ae612e220565fae4541c26c3575 505 Gene3D G3DSA:1.10.1370.10 109 503 2.3E-34 T 28-03-2018 CIG75_RS04615 c2a99ae612e220565fae4541c26c3575 505 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 249 268 1.6E-68 T 28-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CIG75_RS04615 c2a99ae612e220565fae4541c26c3575 505 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 296 312 1.6E-68 T 28-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CIG75_RS04615 c2a99ae612e220565fae4541c26c3575 505 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 232 248 1.6E-68 T 28-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CIG75_RS04615 c2a99ae612e220565fae4541c26c3575 505 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 383 400 1.6E-68 T 28-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CIG75_RS04615 c2a99ae612e220565fae4541c26c3575 505 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 337 356 1.6E-68 T 28-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CIG75_RS04615 c2a99ae612e220565fae4541c26c3575 505 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 153 173 1.6E-68 T 28-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CIG75_RS04615 c2a99ae612e220565fae4541c26c3575 505 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 269 288 1.6E-68 T 28-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CIG75_RS04615 c2a99ae612e220565fae4541c26c3575 505 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 451 469 1.6E-68 T 28-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CIG75_RS04615 c2a99ae612e220565fae4541c26c3575 505 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 406 427 1.6E-68 T 28-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CIG75_RS04615 c2a99ae612e220565fae4541c26c3575 505 PIRSF PIRSF006615 5 505 6.6E-185 T 28-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CIG75_RS05700 2df603c1418790922c0c66018801ff86 115 Pfam PF14325 Domain of unknown function (DUF4383) 4 105 1.3E-15 T 28-03-2018 IPR025492 Protein of unknown function DUF4383 CIG75_RS06925 e19d022dd0b7433b120d283dca114ad4 136 Pfam PF07561 Domain of Unknown Function (DUF1540) 9 52 1.3E-8 T 28-03-2018 IPR011437 Domain of unknown function DUF1540 CIG75_RS06925 e19d022dd0b7433b120d283dca114ad4 136 Pfam PF07561 Domain of Unknown Function (DUF1540) 88 127 5.5E-11 T 28-03-2018 IPR011437 Domain of unknown function DUF1540 CIG75_RS02100 fc774e7022810c52ffe00139ce827817 1018 Pfam PF00395 S-layer homology domain 30 71 5.7E-9 T 28-03-2018 IPR001119 S-layer homology domain CIG75_RS02100 fc774e7022810c52ffe00139ce827817 1018 Pfam PF00395 S-layer homology domain 90 133 2.3E-8 T 28-03-2018 IPR001119 S-layer homology domain CIG75_RS02100 fc774e7022810c52ffe00139ce827817 1018 Pfam PF00395 S-layer homology domain 152 196 5.6E-9 T 28-03-2018 IPR001119 S-layer homology domain CIG75_RS14160 5568944cd65f8b9857f218dd518e4b06 252 SUPERFAMILY SSF53474 4 252 3.82E-49 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS14160 5568944cd65f8b9857f218dd518e4b06 252 Pfam PF12146 Serine aminopeptidase, S33 31 147 3.1E-14 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 CIG75_RS14160 5568944cd65f8b9857f218dd518e4b06 252 Gene3D G3DSA:3.40.50.1820 5 252 3.1E-38 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS01895 0424071855f2cf2b52e7d7c1c720fac2 380 Gene3D G3DSA:3.40.50.2000 4 206 6.3E-77 T 28-03-2018 CIG75_RS01895 0424071855f2cf2b52e7d7c1c720fac2 380 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 5 368 9.5E-160 T 28-03-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 CIG75_RS01895 0424071855f2cf2b52e7d7c1c720fac2 380 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 31 365 2.9E-117 T 28-03-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001 CIG75_RS01895 0424071855f2cf2b52e7d7c1c720fac2 380 Gene3D G3DSA:3.40.50.2000 207 352 2.1E-32 T 28-03-2018 CIG75_RS01895 0424071855f2cf2b52e7d7c1c720fac2 380 SUPERFAMILY SSF53756 4 369 1.73E-130 T 28-03-2018 CIG75_RS02165 ffe4c63893ff27f21050fe5836a44473 322 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 24 316 1.0E-31 T 28-03-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD CIG75_RS02165 ffe4c63893ff27f21050fe5836a44473 322 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 24 309 1.4E-44 T 28-03-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD CIG75_RS00260 2262892b013578e275465c781e5ef1e1 239 Gene3D G3DSA:3.40.50.150 1 239 8.1E-39 T 28-03-2018 CIG75_RS00260 2262892b013578e275465c781e5ef1e1 239 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 28 219 1.5E-45 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CIG75_RS00260 2262892b013578e275465c781e5ef1e1 239 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 16 216 27.113 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CIG75_RS00260 2262892b013578e275465c781e5ef1e1 239 Pfam PF02527 rRNA small subunit methyltransferase G 26 204 5.8E-46 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CIG75_RS00260 2262892b013578e275465c781e5ef1e1 239 SUPERFAMILY SSF53335 10 239 2.89E-43 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CIG75_RS00260 2262892b013578e275465c781e5ef1e1 239 PIRSF PIRSF003078 1 222 4.2E-48 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CIG75_RS15505 86dc06b048ec28d53ef560c0b026d787 366 PRINTS PR00599 Methionine aminopeptidase-1 signature 316 328 4.7E-5 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CIG75_RS15505 86dc06b048ec28d53ef560c0b026d787 366 PRINTS PR00599 Methionine aminopeptidase-1 signature 218 234 4.7E-5 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CIG75_RS15505 86dc06b048ec28d53ef560c0b026d787 366 Gene3D G3DSA:3.40.350.10 4 136 1.0E-27 T 28-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CIG75_RS15505 86dc06b048ec28d53ef560c0b026d787 366 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 294 306 - T 28-03-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site CIG75_RS15505 86dc06b048ec28d53ef560c0b026d787 366 SUPERFAMILY SSF55920 139 364 6.8E-82 T 28-03-2018 IPR000994 Peptidase M24 CIG75_RS15505 86dc06b048ec28d53ef560c0b026d787 366 SUPERFAMILY SSF53092 4 136 1.74E-29 T 28-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal CIG75_RS15505 86dc06b048ec28d53ef560c0b026d787 366 Pfam PF01321 Creatinase/Prolidase N-terminal domain 7 137 4.8E-27 T 28-03-2018 IPR000587 Creatinase, N-terminal GO:0016787 CIG75_RS15505 86dc06b048ec28d53ef560c0b026d787 366 Pfam PF00557 Metallopeptidase family M24 146 348 3.4E-69 T 28-03-2018 IPR000994 Peptidase M24 CIG75_RS15505 86dc06b048ec28d53ef560c0b026d787 366 Gene3D G3DSA:3.90.230.10 137 364 2.1E-82 T 28-03-2018 CIG75_RS19255 ae36b243e315bbca72c2f7065ea2c5c7 83 Pfam PF13560 Helix-turn-helix domain 6 59 1.7E-8 T 28-03-2018 CIG75_RS19255 ae36b243e315bbca72c2f7065ea2c5c7 83 SMART SM00530 5 60 6.4E-9 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS19255 ae36b243e315bbca72c2f7065ea2c5c7 83 SUPERFAMILY SSF47413 4 61 1.18E-10 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CIG75_RS19255 ae36b243e315bbca72c2f7065ea2c5c7 83 Gene3D G3DSA:1.10.260.40 3 61 3.1E-13 T 28-03-2018 CIG75_RS14625 a5e44592722dddfcf581babaccd06927 85 Gene3D G3DSA:2.20.25.10 31 74 0.0034 T 28-03-2018 CIG75_RS17675 a68fd91a82ab038290e9106baf408521 249 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 4 230 5.0E-50 T 28-03-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 CIG75_RS17675 a68fd91a82ab038290e9106baf408521 249 SUPERFAMILY SSF53067 109 228 6.99E-12 T 28-03-2018 CIG75_RS17675 a68fd91a82ab038290e9106baf408521 249 Pfam PF00814 Glycoprotease family 31 179 4.4E-29 T 28-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CIG75_RS17675 a68fd91a82ab038290e9106baf408521 249 Gene3D G3DSA:3.30.420.40 2 138 2.9E-32 T 28-03-2018 CIG75_RS17675 a68fd91a82ab038290e9106baf408521 249 SUPERFAMILY SSF53067 3 102 2.12E-25 T 28-03-2018 CIG75_RS06810 5f2ce200b4c152b292396eaca1d4da4e 431 Gene3D G3DSA:3.90.1150.10 1 166 8.6E-44 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CIG75_RS06810 5f2ce200b4c152b292396eaca1d4da4e 431 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 9 430 4.3E-170 T 28-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 CIG75_RS06810 5f2ce200b4c152b292396eaca1d4da4e 431 Pfam PF00202 Aminotransferase class-III 38 402 4.8E-71 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CIG75_RS06810 5f2ce200b4c152b292396eaca1d4da4e 431 SUPERFAMILY SSF53383 5 430 1.89E-125 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CIG75_RS06810 5f2ce200b4c152b292396eaca1d4da4e 431 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 8 431 94.231 T 28-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 CIG75_RS06810 5f2ce200b4c152b292396eaca1d4da4e 431 Gene3D G3DSA:3.40.640.10 170 318 7.9E-39 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CIG75_RS06810 5f2ce200b4c152b292396eaca1d4da4e 431 Gene3D G3DSA:3.90.1150.10 319 431 2.4E-16 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CIG75_RS06810 5f2ce200b4c152b292396eaca1d4da4e 431 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 240 276 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CIG75_RS16980 b72a9cd6707bdab6ac09951a1d661c92 282 Gene3D G3DSA:3.40.50.720 2 185 1.6E-45 T 28-03-2018 CIG75_RS16980 b72a9cd6707bdab6ac09951a1d661c92 282 SUPERFAMILY SSF48179 185 282 8.5E-30 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CIG75_RS16980 b72a9cd6707bdab6ac09951a1d661c92 282 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 186 282 2.1E-30 T 28-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CIG75_RS16980 b72a9cd6707bdab6ac09951a1d661c92 282 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 4 183 6.7E-52 T 28-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CIG75_RS16980 b72a9cd6707bdab6ac09951a1d661c92 282 SUPERFAMILY SSF51735 4 185 3.54E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS16980 b72a9cd6707bdab6ac09951a1d661c92 282 Gene3D G3DSA:1.10.1040.10 186 282 2.6E-29 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CIG75_RS16980 b72a9cd6707bdab6ac09951a1d661c92 282 PIRSF PIRSF000105 1 282 1.0E-77 T 28-03-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 CIG75_RS04965 37c64744c47c9c08fc2bb18b6f6b03af 61 Gene3D G3DSA:2.60.300.12 1 61 2.9E-7 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CIG75_RS04965 37c64744c47c9c08fc2bb18b6f6b03af 61 SUPERFAMILY SSF89360 7 53 2.35E-5 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CIG75_RS09660 614d320ec4b358f3cf5f0266d0266816 321 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 81 95 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site CIG75_RS09660 614d320ec4b358f3cf5f0266d0266816 321 Gene3D G3DSA:1.10.600.10 1 321 3.7E-99 T 28-03-2018 IPR008949 Isoprenoid synthase domain CIG75_RS09660 614d320ec4b358f3cf5f0266d0266816 321 SUPERFAMILY SSF48576 3 320 1.57E-88 T 28-03-2018 IPR008949 Isoprenoid synthase domain CIG75_RS09660 614d320ec4b358f3cf5f0266d0266816 321 Pfam PF00348 Polyprenyl synthetase 31 272 4.2E-71 T 28-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 CIG75_RS11650 efadd163afc211aceabf58c7b8260cdb 73 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 23 32 - T 28-03-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 CIG75_RS11650 efadd163afc211aceabf58c7b8260cdb 73 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 8 62 1.6E-21 T 28-03-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 CIG75_RS20445 d5c277e51c5876c2cc83fab6272a96ec 264 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 197 213 - T 28-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 CIG75_RS20445 d5c277e51c5876c2cc83fab6272a96ec 264 Pfam PF01026 TatD related DNase 7 260 1.6E-85 T 28-03-2018 IPR001130 TatD family GO:0016788 CIG75_RS20445 d5c277e51c5876c2cc83fab6272a96ec 264 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 6 14 - T 28-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 CIG75_RS20445 d5c277e51c5876c2cc83fab6272a96ec 264 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 6 261 9.6E-92 T 28-03-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 CIG75_RS20445 d5c277e51c5876c2cc83fab6272a96ec 264 SUPERFAMILY SSF51556 6 262 8.52E-97 T 28-03-2018 IPR032466 Metal-dependent hydrolase CIG75_RS20445 d5c277e51c5876c2cc83fab6272a96ec 264 PIRSF PIRSF005902 1 264 4.4E-93 T 28-03-2018 IPR001130 TatD family GO:0016788 CIG75_RS20445 d5c277e51c5876c2cc83fab6272a96ec 264 Gene3D G3DSA:3.20.20.140 4 264 4.9E-95 T 28-03-2018 CIG75_RS00590 7324af5f6d6c13e027cdd2e3500b5e9d 129 SUPERFAMILY SSF55021 65 128 1.04E-19 T 28-03-2018 CIG75_RS00590 7324af5f6d6c13e027cdd2e3500b5e9d 129 SUPERFAMILY SSF55021 2 57 2.59E-10 T 28-03-2018 CIG75_RS00590 7324af5f6d6c13e027cdd2e3500b5e9d 129 Gene3D G3DSA:3.30.2130.10 1 127 4.9E-31 T 28-03-2018 CIG75_RS00590 7324af5f6d6c13e027cdd2e3500b5e9d 129 PIRSF PIRSF008459 2 129 5.2E-33 T 28-03-2018 IPR016540 Uncharacterised conserved protein UCP008459 CIG75_RS00590 7324af5f6d6c13e027cdd2e3500b5e9d 129 Pfam PF13840 ACT domain 61 122 1.9E-23 T 28-03-2018 IPR027795 GATS-like ACT domain CIG75_RS03505 fb242a0680ce23b5d0a56eca5b5d083a 245 Pfam PF00881 Nitroreductase family 10 162 5.7E-19 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CIG75_RS03505 fb242a0680ce23b5d0a56eca5b5d083a 245 PIRSF PIRSF005426 1 245 5.7E-95 T 28-03-2018 IPR016446 Flavin oxidoreductase Frp family GO:0016491|GO:0055114 CIG75_RS03505 fb242a0680ce23b5d0a56eca5b5d083a 245 SUPERFAMILY SSF55469 1 244 1.31E-71 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CIG75_RS03505 fb242a0680ce23b5d0a56eca5b5d083a 245 Gene3D G3DSA:3.40.109.10 1 244 4.4E-62 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CIG75_RS02935 4970fb5eb47132593229e02042a651da 384 PIRSF PIRSF015582 14 384 5.2E-66 T 28-03-2018 IPR011206 Citrate lyase beta subunit-like CIG75_RS02935 4970fb5eb47132593229e02042a651da 384 Pfam PF15617 C-C_Bond_Lyase of the TIM-Barrel fold 31 376 2.1E-115 T 28-03-2018 CIG75_RS02935 4970fb5eb47132593229e02042a651da 384 SUPERFAMILY SSF51621 35 259 7.38E-18 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CIG75_RS02935 4970fb5eb47132593229e02042a651da 384 SUPERFAMILY SSF51621 287 322 7.38E-18 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CIG75_RS02935 4970fb5eb47132593229e02042a651da 384 Gene3D G3DSA:3.20.20.360 23 345 6.1E-32 T 28-03-2018 CIG75_RS06380 fd783c43e7e8ca31e63770b2d0718248 84 Pfam PF13797 Post-transcriptional regulator 14 83 1.7E-14 T 28-03-2018 IPR025716 Post-transcriptional regulator CIG75_RS13935 1c052eec01794f4399739b56bdf38776 410 Pfam PF09546 Stage III sporulation protein AE (spore_III_AE) 87 403 4.1E-105 T 28-03-2018 IPR014194 Sporulation stage III, protein AE CIG75_RS13935 1c052eec01794f4399739b56bdf38776 410 TIGRFAM TIGR02829 spore_III_AE: stage III sporulation protein AE 54 402 2.3E-120 T 28-03-2018 IPR014194 Sporulation stage III, protein AE CIG75_RS07865 69b476d286f4fc9aec10d70c087c363f 304 SUPERFAMILY SSF103481 41 142 1.57E-11 T 28-03-2018 CIG75_RS07865 69b476d286f4fc9aec10d70c087c363f 304 Pfam PF00892 EamA-like transporter family 148 286 1.7E-17 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CIG75_RS07865 69b476d286f4fc9aec10d70c087c363f 304 Pfam PF00892 EamA-like transporter family 8 140 2.1E-21 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CIG75_RS07865 69b476d286f4fc9aec10d70c087c363f 304 SUPERFAMILY SSF103481 212 292 4.32E-12 T 28-03-2018 CIG75_RS03840 302f16d49315654b6d96397b83264b3c 308 Gene3D G3DSA:3.40.50.10330 1 134 1.5E-33 T 28-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 CIG75_RS03840 302f16d49315654b6d96397b83264b3c 308 SMART SM00046 6 133 5.2E-5 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CIG75_RS03840 302f16d49315654b6d96397b83264b3c 308 SUPERFAMILY SSF111331 5 299 1.83E-82 T 28-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain CIG75_RS03840 302f16d49315654b6d96397b83264b3c 308 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 6 296 1.1E-88 T 28-03-2018 IPR005218 Diacylglycerol/lipid kinase CIG75_RS03840 302f16d49315654b6d96397b83264b3c 308 Pfam PF00781 Diacylglycerol kinase catalytic domain 7 130 1.6E-34 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CIG75_RS16890 5370bf8f53e37982ac7937aa2cdfeba4 241 TIGRFAM TIGR00317 cobS: cobalamin 5'-phosphate synthase 8 238 1.5E-44 T 28-03-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CIG75_RS16890 5370bf8f53e37982ac7937aa2cdfeba4 241 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 241 44.776 T 28-03-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CIG75_RS16890 5370bf8f53e37982ac7937aa2cdfeba4 241 Pfam PF02654 Cobalamin-5-phosphate synthase 13 236 3.6E-57 T 28-03-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CIG75_RS03315 b89d5467ee57e378a9021a8e92902dab 107 SMART SM00418 9 90 1.4E-24 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CIG75_RS03315 b89d5467ee57e378a9021a8e92902dab 107 Pfam PF01022 Bacterial regulatory protein, arsR family 16 61 8.4E-15 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CIG75_RS03315 b89d5467ee57e378a9021a8e92902dab 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 58 73 5.0E-13 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CIG75_RS03315 b89d5467ee57e378a9021a8e92902dab 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 43 58 5.0E-13 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CIG75_RS03315 b89d5467ee57e378a9021a8e92902dab 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 11 26 5.0E-13 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CIG75_RS03315 b89d5467ee57e378a9021a8e92902dab 107 Gene3D G3DSA:1.10.10.10 2 107 1.4E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS03315 b89d5467ee57e378a9021a8e92902dab 107 SUPERFAMILY SSF46785 8 102 5.55E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS16855 8f6d4e0a03cee007577096eec4394c26 345 Gene3D G3DSA:1.10.3470.10 17 345 8.0E-70 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CIG75_RS16855 8f6d4e0a03cee007577096eec4394c26 345 SUPERFAMILY SSF81345 18 341 1.57E-81 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CIG75_RS16855 8f6d4e0a03cee007577096eec4394c26 345 Pfam PF01032 FecCD transport family 32 341 3.9E-91 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CIG75_RS09750 feba491288a01cf8baf3ba183fed5eb0 338 Pfam PF03601 Conserved hypothetical protein 698 20 315 3.6E-77 T 28-03-2018 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 CIG75_RS15120 f6b203c773d02047e137cb0cfcffeb39 329 SMART SM00382 52 239 1.3E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS15120 f6b203c773d02047e137cb0cfcffeb39 329 Gene3D G3DSA:3.40.50.300 4 305 4.3E-50 T 28-03-2018 CIG75_RS15120 f6b203c773d02047e137cb0cfcffeb39 329 Pfam PF00005 ABC transporter 44 187 3.6E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS15120 f6b203c773d02047e137cb0cfcffeb39 329 SUPERFAMILY SSF52540 40 257 1.36E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS04505 4801e29825c6a7d1ac0aa6b0e3b9eaf8 57 SUPERFAMILY SSF55811 3 53 2.98E-7 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CIG75_RS04505 4801e29825c6a7d1ac0aa6b0e3b9eaf8 57 Gene3D G3DSA:3.90.79.10 1 57 7.1E-7 T 28-03-2018 CIG75_RS08060 06c5d1913fc7d376d946e2eb6f1137b8 199 Pfam PF02545 Maf-like protein 6 187 3.1E-56 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 CIG75_RS08060 06c5d1913fc7d376d946e2eb6f1137b8 199 Hamap MF_00528 Septum formation protein Maf [maf]. 5 192 32.111 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 CIG75_RS08060 06c5d1913fc7d376d946e2eb6f1137b8 199 TIGRFAM TIGR00172 maf: septum formation protein Maf 5 184 2.7E-56 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 CIG75_RS08060 06c5d1913fc7d376d946e2eb6f1137b8 199 Gene3D G3DSA:3.90.950.10 4 195 2.1E-67 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CIG75_RS08060 06c5d1913fc7d376d946e2eb6f1137b8 199 PIRSF PIRSF006305 1 194 3.2E-51 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 CIG75_RS08060 06c5d1913fc7d376d946e2eb6f1137b8 199 SUPERFAMILY SSF52972 3 187 9.81E-61 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CIG75_RS03575 6d377cf8fd58404aebe0a208d9f0d314 390 Pfam PF05977 Transmembrane secretion effector 9 382 6.8E-43 T 28-03-2018 IPR010290 Transmembrane secretion effector CIG75_RS03575 6d377cf8fd58404aebe0a208d9f0d314 390 Gene3D G3DSA:1.20.1250.20 1 194 1.3E-22 T 28-03-2018 CIG75_RS03575 6d377cf8fd58404aebe0a208d9f0d314 390 SUPERFAMILY SSF103473 2 387 4.05E-48 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS03575 6d377cf8fd58404aebe0a208d9f0d314 390 Gene3D G3DSA:1.20.1250.20 195 386 5.2E-17 T 28-03-2018 CIG75_RS05995 86aded6661c716f930dd004107c539f4 119 Gene3D G3DSA:1.10.1900.20 55 116 1.3E-27 T 28-03-2018 IPR035566 Ribosomal protein L20 C-terminal domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS05995 86aded6661c716f930dd004107c539f4 119 Pfam PF00453 Ribosomal protein L20 3 109 6.2E-48 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS05995 86aded6661c716f930dd004107c539f4 119 SUPERFAMILY SSF74731 2 115 7.98E-49 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS05995 86aded6661c716f930dd004107c539f4 119 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 30.381 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS05995 86aded6661c716f930dd004107c539f4 119 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 114 1.2E-49 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS05995 86aded6661c716f930dd004107c539f4 119 PRINTS PR00062 Ribosomal protein L20 signature 12 41 1.5E-41 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS05995 86aded6661c716f930dd004107c539f4 119 PRINTS PR00062 Ribosomal protein L20 signature 75 101 1.5E-41 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS05995 86aded6661c716f930dd004107c539f4 119 PRINTS PR00062 Ribosomal protein L20 signature 42 71 1.5E-41 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS05995 86aded6661c716f930dd004107c539f4 119 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS05995 86aded6661c716f930dd004107c539f4 119 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 20 61 5.0E-5 T 28-03-2018 CIG75_RS15160 2ed4522b3c88780fb3295ce3e635bbfd 397 Gene3D G3DSA:3.40.50.150 42 314 2.4E-17 T 28-03-2018 CIG75_RS15160 2ed4522b3c88780fb3295ce3e635bbfd 397 SUPERFAMILY SSF53335 155 287 5.57E-17 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CIG75_RS15160 2ed4522b3c88780fb3295ce3e635bbfd 397 Pfam PF13679 Methyltransferase domain 154 291 9.2E-37 T 28-03-2018 IPR025714 Methyltransferase domain CIG75_RS01320 94692694fd51ac76624e4ab38508ab46 411 Pfam PF03738 Glutathionylspermidine synthase preATP-grasp 20 409 1.2E-68 T 28-03-2018 IPR005494 Glutathionylspermidine synthase, pre-ATP-grasp-like domain CIG75_RS01320 94692694fd51ac76624e4ab38508ab46 411 SUPERFAMILY SSF56059 271 407 1.09E-42 T 28-03-2018 CIG75_RS01320 94692694fd51ac76624e4ab38508ab46 411 SUPERFAMILY SSF56059 20 159 1.09E-42 T 28-03-2018 CIG75_RS13860 b7ec00c8dbbf8bc3403df3cbd549f130 120 Gene3D G3DSA:3.30.240.20 41 109 2.4E-8 T 28-03-2018 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain CIG75_RS19565 2ba17d6555ac9d582dc80e55ca387dbe 240 TIGRFAM TIGR02883 spore_cwlD: N-acetylmuramoyl-L-alanine amidase CwlD 49 236 4.8E-71 T 28-03-2018 IPR014234 N-acetylmuramoyl-L-alanine amidase CwlD CIG75_RS19565 2ba17d6555ac9d582dc80e55ca387dbe 240 SMART SM00646 124 234 1.7E-25 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CIG75_RS19565 2ba17d6555ac9d582dc80e55ca387dbe 240 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 51 234 1.3E-46 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CIG75_RS19565 2ba17d6555ac9d582dc80e55ca387dbe 240 SUPERFAMILY SSF53187 50 238 9.04E-48 T 28-03-2018 CIG75_RS19565 2ba17d6555ac9d582dc80e55ca387dbe 240 Gene3D G3DSA:3.40.630.40 36 240 3.8E-53 T 28-03-2018 CIG75_RS03430 e62255079400a21409c57e96a93528f6 499 Pfam PF00206 Lyase 101 302 5.8E-24 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal CIG75_RS03430 e62255079400a21409c57e96a93528f6 499 Gene3D G3DSA:1.20.200.10 128 494 3.7E-65 T 28-03-2018 CIG75_RS03430 e62255079400a21409c57e96a93528f6 499 Gene3D G3DSA:1.10.275.10 37 127 0.0031 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal CIG75_RS03430 e62255079400a21409c57e96a93528f6 499 PRINTS PR00149 Fumarate lyase superfamily signature 240 267 3.4E-8 T 28-03-2018 IPR000362 Fumarate lyase family CIG75_RS03430 e62255079400a21409c57e96a93528f6 499 PRINTS PR00149 Fumarate lyase superfamily signature 284 300 3.4E-8 T 28-03-2018 IPR000362 Fumarate lyase family CIG75_RS03430 e62255079400a21409c57e96a93528f6 499 PRINTS PR00149 Fumarate lyase superfamily signature 156 174 3.4E-8 T 28-03-2018 IPR000362 Fumarate lyase family CIG75_RS03430 e62255079400a21409c57e96a93528f6 499 PRINTS PR00145 Argininosuccinate lyase family signature 202 218 1.2E-19 T 28-03-2018 CIG75_RS03430 e62255079400a21409c57e96a93528f6 499 PRINTS PR00145 Argininosuccinate lyase family signature 110 132 1.2E-19 T 28-03-2018 CIG75_RS03430 e62255079400a21409c57e96a93528f6 499 PRINTS PR00145 Argininosuccinate lyase family signature 240 264 1.2E-19 T 28-03-2018 CIG75_RS03430 e62255079400a21409c57e96a93528f6 499 PRINTS PR00145 Argininosuccinate lyase family signature 284 300 1.2E-19 T 28-03-2018 CIG75_RS03430 e62255079400a21409c57e96a93528f6 499 PRINTS PR00145 Argininosuccinate lyase family signature 151 171 1.2E-19 T 28-03-2018 CIG75_RS03430 e62255079400a21409c57e96a93528f6 499 SUPERFAMILY SSF48557 39 469 2.98E-73 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 CIG75_RS19140 90a16c74962df4de42148427423be0ba 102 Gene3D G3DSA:1.10.287.1080 9 52 0.25 T 28-03-2018 CIG75_RS16205 33a91b9a197c673d9f0066bfdd998c47 259 Gene3D G3DSA:3.40.50.300 12 210 8.1E-20 T 28-03-2018 CIG75_RS16205 33a91b9a197c673d9f0066bfdd998c47 259 SUPERFAMILY SSF52540 22 191 4.32E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS16205 33a91b9a197c673d9f0066bfdd998c47 259 Pfam PF00005 ABC transporter 23 133 7.9E-8 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS08940 f90307256df2a1f126f900fa44bc0d4a 471 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 320 327 - T 28-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CIG75_RS08940 f90307256df2a1f126f900fa44bc0d4a 471 PRINTS PR00481 Cytosol aminopeptidase signature 257 278 3.4E-43 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CIG75_RS08940 f90307256df2a1f126f900fa44bc0d4a 471 PRINTS PR00481 Cytosol aminopeptidase signature 344 359 3.4E-43 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CIG75_RS08940 f90307256df2a1f126f900fa44bc0d4a 471 PRINTS PR00481 Cytosol aminopeptidase signature 235 252 3.4E-43 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CIG75_RS08940 f90307256df2a1f126f900fa44bc0d4a 471 PRINTS PR00481 Cytosol aminopeptidase signature 294 315 3.4E-43 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CIG75_RS08940 f90307256df2a1f126f900fa44bc0d4a 471 PRINTS PR00481 Cytosol aminopeptidase signature 316 336 3.4E-43 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CIG75_RS08940 f90307256df2a1f126f900fa44bc0d4a 471 SUPERFAMILY SSF53187 156 469 3.61E-106 T 28-03-2018 CIG75_RS08940 f90307256df2a1f126f900fa44bc0d4a 471 Gene3D G3DSA:3.40.220.10 9 135 4.0E-20 T 28-03-2018 CIG75_RS08940 f90307256df2a1f126f900fa44bc0d4a 471 SUPERFAMILY SSF52949 29 158 2.12E-18 T 28-03-2018 CIG75_RS08940 f90307256df2a1f126f900fa44bc0d4a 471 Gene3D G3DSA:3.40.630.10 144 471 2.4E-121 T 28-03-2018 CIG75_RS08940 f90307256df2a1f126f900fa44bc0d4a 471 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 160 465 1.6E-108 T 28-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CIG75_RS08940 f90307256df2a1f126f900fa44bc0d4a 471 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 1 471 30.064 T 28-03-2018 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 CIG75_RS08940 f90307256df2a1f126f900fa44bc0d4a 471 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 29 124 4.8E-14 T 28-03-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CIG75_RS03605 2296fdbaf276e6ceba3d70367238d116 709 Gene3D G3DSA:3.40.50.300 531 708 2.9E-28 T 28-03-2018 CIG75_RS03605 2296fdbaf276e6ceba3d70367238d116 709 SUPERFAMILY SSF52540 419 701 1.02E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS03605 2296fdbaf276e6ceba3d70367238d116 709 SUPERFAMILY SSF52540 179 337 1.02E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS03605 2296fdbaf276e6ceba3d70367238d116 709 Gene3D G3DSA:3.40.50.300 184 529 1.5E-33 T 28-03-2018 CIG75_RS03605 2296fdbaf276e6ceba3d70367238d116 709 Pfam PF13538 UvrD-like helicase C-terminal domain 638 685 9.0E-10 T 28-03-2018 IPR027785 UvrD-like helicase C-terminal domain CIG75_RS03605 2296fdbaf276e6ceba3d70367238d116 709 Pfam PF13245 AAA domain 190 507 2.2E-10 T 28-03-2018 CIG75_RS16340 9b670fd15c1e6429061ff03d5521991b 207 Pfam PF09876 Predicted metal-binding protein (DUF2103) 9 87 1.6E-9 T 28-03-2018 IPR018664 Protein of unknown function DUF2103, metal-binding CIG75_RS16340 9b670fd15c1e6429061ff03d5521991b 207 Pfam PF13025 Protein of unknown function (DUF3886) 137 205 1.4E-15 T 28-03-2018 IPR024980 Protein of unknown function DUF3886 CIG75_RS00990 281c602034cc4fb4033164a6e58362ce 336 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 11 332 8.2E-138 T 28-03-2018 IPR019949 Luciferase family oxidoreductase, group 1 CIG75_RS00990 281c602034cc4fb4033164a6e58362ce 336 Pfam PF00296 Luciferase-like monooxygenase 24 309 1.8E-37 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CIG75_RS00990 281c602034cc4fb4033164a6e58362ce 336 Gene3D G3DSA:3.20.20.30 13 336 6.2E-78 T 28-03-2018 CIG75_RS00990 281c602034cc4fb4033164a6e58362ce 336 SUPERFAMILY SSF51679 9 331 1.77E-90 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CIG75_RS16920 c16e717fbe7a3f626146cf3d62166af3 244 Gene3D G3DSA:3.30.950.10 152 230 2.4E-4 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CIG75_RS16920 c16e717fbe7a3f626146cf3d62166af3 244 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 14 225 1.9E-51 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CIG75_RS16920 c16e717fbe7a3f626146cf3d62166af3 244 SUPERFAMILY SSF53790 9 243 2.62E-48 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CIG75_RS16920 c16e717fbe7a3f626146cf3d62166af3 244 Gene3D G3DSA:3.40.1010.10 12 151 5.4E-32 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CIG75_RS16920 c16e717fbe7a3f626146cf3d62166af3 244 TIGRFAM TIGR01467 cobI_cbiL: precorrin-2 C(20)-methyltransferase 13 244 6.6E-80 T 28-03-2018 IPR006364 Precorrin-2 C(20)-methyltransferase domain GO:0008757|GO:0009236 CIG75_RS16920 c16e717fbe7a3f626146cf3d62166af3 244 PIRSF PIRSF036427 11 244 3.2E-76 T 28-03-2018 IPR012382 Precorrin-2 C(20)-methyltransferase GO:0008757|GO:0009236|GO:0030788 CIG75_RS04025 8bbc7a48769c123a75696a356cc795de 185 SUPERFAMILY SSF55729 6 180 6.5E-42 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CIG75_RS04025 8bbc7a48769c123a75696a356cc795de 185 Pfam PF13302 Acetyltransferase (GNAT) domain 12 155 5.3E-29 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CIG75_RS04025 8bbc7a48769c123a75696a356cc795de 185 Gene3D G3DSA:3.40.630.30 5 182 4.7E-29 T 28-03-2018 CIG75_RS02500 42093635cbd4b93168bca13599268e85 250 Pfam PF13490 Putative zinc-finger 46 81 1.6E-6 T 28-03-2018 IPR027383 Putative zinc-finger CIG75_RS16865 9c474de0a81bde2f1e9868b84933ae6c 257 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 2 238 3.7E-98 T 28-03-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0006779|GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CIG75_RS16865 9c474de0a81bde2f1e9868b84933ae6c 257 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 2 214 4.8E-49 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CIG75_RS16865 9c474de0a81bde2f1e9868b84933ae6c 257 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 6 20 - T 28-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CIG75_RS16865 9c474de0a81bde2f1e9868b84933ae6c 257 Gene3D G3DSA:3.40.1010.10 1 125 5.6E-37 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CIG75_RS16865 9c474de0a81bde2f1e9868b84933ae6c 257 Gene3D G3DSA:3.30.950.10 126 257 2.0E-40 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CIG75_RS16865 9c474de0a81bde2f1e9868b84933ae6c 257 SUPERFAMILY SSF53790 2 249 2.22E-84 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CIG75_RS16865 9c474de0a81bde2f1e9868b84933ae6c 257 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 81 114 - T 28-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CIG75_RS07400 e1ad2446657438399a479cfe7df06e9f 290 Pfam PF01904 Protein of unknown function DUF72 18 264 7.9E-60 T 28-03-2018 IPR002763 Protein of unknown function DUF72 CIG75_RS07400 e1ad2446657438399a479cfe7df06e9f 290 Gene3D G3DSA:3.20.20.410 1 283 2.5E-77 T 28-03-2018 IPR002763 Protein of unknown function DUF72 CIG75_RS07400 e1ad2446657438399a479cfe7df06e9f 290 SUPERFAMILY SSF117396 3 268 3.14E-76 T 28-03-2018 IPR002763 Protein of unknown function DUF72 CIG75_RS06425 85586ee165c8b79a05d1cccd864b1cbc 134 PIRSF PIRSF016498 3 134 6.7E-25 T 28-03-2018 IPR018699 Protein of unknown function DUF2203 CIG75_RS06425 85586ee165c8b79a05d1cccd864b1cbc 134 Pfam PF09969 Uncharacterized conserved protein (DUF2203) 5 132 1.2E-36 T 28-03-2018 IPR018699 Protein of unknown function DUF2203 CIG75_RS08185 8a3aacd0338ef4d3f4a65b453db4bccd 119 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 8 29 1.9E-5 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site CIG75_RS08185 8a3aacd0338ef4d3f4a65b453db4bccd 119 Pfam PF07963 Prokaryotic N-terminal methylation motif 5 29 1.6E-6 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site CIG75_RS02860 d5e6cd54ffd45ce8be320c000016ed47 412 PRINTS PR01035 Tetracycline resistance protein signature 109 130 1.8E-13 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CIG75_RS02860 d5e6cd54ffd45ce8be320c000016ed47 412 PRINTS PR01035 Tetracycline resistance protein signature 348 371 1.8E-13 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CIG75_RS02860 d5e6cd54ffd45ce8be320c000016ed47 412 PRINTS PR01035 Tetracycline resistance protein signature 21 37 1.8E-13 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CIG75_RS02860 d5e6cd54ffd45ce8be320c000016ed47 412 PRINTS PR01035 Tetracycline resistance protein signature 139 161 1.8E-13 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CIG75_RS02860 d5e6cd54ffd45ce8be320c000016ed47 412 PRINTS PR01035 Tetracycline resistance protein signature 82 106 1.8E-13 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CIG75_RS02860 d5e6cd54ffd45ce8be320c000016ed47 412 PRINTS PR01035 Tetracycline resistance protein signature 51 70 1.8E-13 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CIG75_RS02860 d5e6cd54ffd45ce8be320c000016ed47 412 SUPERFAMILY SSF103473 8 402 3.14E-64 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS02860 d5e6cd54ffd45ce8be320c000016ed47 412 Gene3D G3DSA:1.20.1250.20 206 402 9.3E-24 T 28-03-2018 CIG75_RS02860 d5e6cd54ffd45ce8be320c000016ed47 412 Gene3D G3DSA:1.20.1250.20 1 205 4.4E-36 T 28-03-2018 CIG75_RS02860 d5e6cd54ffd45ce8be320c000016ed47 412 Pfam PF07690 Major Facilitator Superfamily 15 304 6.5E-42 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CIG75_RS16815 6eefa9ce82c5e0899137881ae6ac9d91 395 Gene3D G3DSA:1.25.40.10 239 393 7.3E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS16815 6eefa9ce82c5e0899137881ae6ac9d91 395 Gene3D G3DSA:1.25.40.10 117 238 1.5E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS16815 6eefa9ce82c5e0899137881ae6ac9d91 395 SMART SM00530 20 77 3.2E-5 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS16815 6eefa9ce82c5e0899137881ae6ac9d91 395 Gene3D G3DSA:1.10.260.40 2 110 2.7E-10 T 28-03-2018 CIG75_RS16815 6eefa9ce82c5e0899137881ae6ac9d91 395 SUPERFAMILY SSF47413 14 79 1.6E-6 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CIG75_RS16815 6eefa9ce82c5e0899137881ae6ac9d91 395 SUPERFAMILY SSF48452 124 328 3.69E-16 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS05680 86bc36ae46f5bfb928e990bdcaa309fb 129 Pfam PF09682 Bacteriophage holin of superfamily 6 (Holin_LLH) 15 106 7.5E-7 T 28-03-2018 IPR010026 Phage holin, LL-H family CIG75_RS11885 2eda7ee5cc3944ebd4b812ddf55c790f 239 Pfam PF00696 Amino acid kinase family 7 217 1.0E-28 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CIG75_RS11885 2eda7ee5cc3944ebd4b812ddf55c790f 239 Hamap MF_01220_B Uridylate kinase [pyrH]. 4 238 45.523 T 28-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 CIG75_RS11885 2eda7ee5cc3944ebd4b812ddf55c790f 239 PIRSF PIRSF005650 1 239 6.0E-97 T 28-03-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 CIG75_RS11885 2eda7ee5cc3944ebd4b812ddf55c790f 239 SUPERFAMILY SSF53633 4 238 1.13E-73 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CIG75_RS11885 2eda7ee5cc3944ebd4b812ddf55c790f 239 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 6 238 1.3E-101 T 28-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 CIG75_RS11885 2eda7ee5cc3944ebd4b812ddf55c790f 239 Gene3D G3DSA:3.40.1160.10 2 239 1.5E-45 T 28-03-2018 CIG75_RS14845 f5836b6a207d856ed68fd71c2729b16d 439 SUPERFAMILY SSF48452 24 151 1.77E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS14845 f5836b6a207d856ed68fd71c2729b16d 439 SMART SM00028 114 147 0.016 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS14845 f5836b6a207d856ed68fd71c2729b16d 439 SMART SM00028 80 113 360.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS14845 f5836b6a207d856ed68fd71c2729b16d 439 Gene3D G3DSA:1.25.40.10 99 411 1.8E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS14845 f5836b6a207d856ed68fd71c2729b16d 439 Gene3D G3DSA:1.25.40.10 14 98 3.8E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS20110 afe80c9ba9bb915e8d0959a3fa361b8d 307 SUPERFAMILY SSF53686 1 305 3.93E-106 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CIG75_RS20110 afe80c9ba9bb915e8d0959a3fa361b8d 307 TIGRFAM TIGR01139 cysK: cysteine synthase A 8 304 5.7E-144 T 28-03-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 CIG75_RS20110 afe80c9ba9bb915e8d0959a3fa361b8d 307 Gene3D G3DSA:3.40.50.1100 140 306 3.8E-58 T 28-03-2018 CIG75_RS20110 afe80c9ba9bb915e8d0959a3fa361b8d 307 Gene3D G3DSA:3.40.50.1100 41 139 7.7E-42 T 28-03-2018 CIG75_RS20110 afe80c9ba9bb915e8d0959a3fa361b8d 307 TIGRFAM TIGR01136 cysKM: cysteine synthase 7 304 5.4E-138 T 28-03-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 CIG75_RS20110 afe80c9ba9bb915e8d0959a3fa361b8d 307 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 8 291 1.1E-72 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CIG75_RS20110 afe80c9ba9bb915e8d0959a3fa361b8d 307 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 28-03-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 CIG75_RS14685 a0ab76e9eac63a98e5369f1c3a4a1a73 269 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 3 252 9.3E-53 T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CIG75_RS14685 a0ab76e9eac63a98e5369f1c3a4a1a73 269 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 4 247 2.6E-59 T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CIG75_RS14685 a0ab76e9eac63a98e5369f1c3a4a1a73 269 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 1 252 15.087 T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CIG75_RS01105 21a8e8f4ffb99409778e149890fadfcb 303 Gene3D G3DSA:3.40.50.1820 21 303 1.7E-36 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS01105 21a8e8f4ffb99409778e149890fadfcb 303 Pfam PF00326 Prolyl oligopeptidase family 114 302 2.8E-24 T 28-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 CIG75_RS01105 21a8e8f4ffb99409778e149890fadfcb 303 SUPERFAMILY SSF53474 67 302 2.2E-40 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS17940 68c8588ac0a86dd62f9bf6bd1210a21f 90 SUPERFAMILY SSF47598 3 46 1.0E-8 T 28-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 CIG75_RS17940 68c8588ac0a86dd62f9bf6bd1210a21f 90 Pfam PF01402 Ribbon-helix-helix protein, copG family 6 42 3.1E-5 T 28-03-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 CIG75_RS17940 68c8588ac0a86dd62f9bf6bd1210a21f 90 Gene3D G3DSA:1.10.1220.10 5 57 9.1E-14 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CIG75_RS05970 36eec761cc1027e34484a4fabb488252 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 221 1.3E-24 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CIG75_RS05970 36eec761cc1027e34484a4fabb488252 228 SUPERFAMILY SSF46894 128 222 5.39E-28 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CIG75_RS05970 36eec761cc1027e34484a4fabb488252 228 SUPERFAMILY SSF52172 1 118 1.41E-39 T 28-03-2018 IPR011006 CheY-like superfamily CIG75_RS05970 36eec761cc1027e34484a4fabb488252 228 Gene3D G3DSA:3.40.50.2300 1 113 4.7E-39 T 28-03-2018 CIG75_RS05970 36eec761cc1027e34484a4fabb488252 228 SMART SM00862 146 221 1.5E-27 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CIG75_RS05970 36eec761cc1027e34484a4fabb488252 228 Gene3D G3DSA:1.10.10.10 114 227 1.1E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS05970 36eec761cc1027e34484a4fabb488252 228 Pfam PF00072 Response regulator receiver domain 3 112 2.4E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CIG75_RS05970 36eec761cc1027e34484a4fabb488252 228 SMART SM00448 1 112 3.5E-41 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CIG75_RS19810 b80c8e35a05530fa08585edb8099ef24 49 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 3 49 1.2E-19 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS19810 b80c8e35a05530fa08585edb8099ef24 49 Pfam PF00471 Ribosomal protein L33 3 49 1.2E-22 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS19810 b80c8e35a05530fa08585edb8099ef24 49 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 1 49 19.428 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS19810 b80c8e35a05530fa08585edb8099ef24 49 ProSitePatterns PS00582 Ribosomal protein L33 signature. 17 36 - T 28-03-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS19810 b80c8e35a05530fa08585edb8099ef24 49 SUPERFAMILY SSF57829 1 49 6.71E-19 T 28-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 CIG75_RS17120 7276032b1c6d0f83108bf3f7b7d49166 516 Gene3D G3DSA:1.25.40.10 87 175 0.15 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS17120 7276032b1c6d0f83108bf3f7b7d49166 516 Gene3D G3DSA:1.25.40.10 211 246 3.7E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS17120 7276032b1c6d0f83108bf3f7b7d49166 516 Gene3D G3DSA:1.25.40.10 176 210 6.0E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS17120 7276032b1c6d0f83108bf3f7b7d49166 516 SUPERFAMILY SSF48452 166 286 2.98E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS17120 7276032b1c6d0f83108bf3f7b7d49166 516 Pfam PF14559 Tetratricopeptide repeat 166 221 7.7E-7 T 28-03-2018 CIG75_RS01620 b3259d91e050c57e68ebe995fcb02c06 381 SUPERFAMILY SSF47203 228 380 8.38E-63 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CIG75_RS01620 b3259d91e050c57e68ebe995fcb02c06 381 PIRSF PIRSF016578 3 378 2.0E-28 T 28-03-2018 CIG75_RS01620 b3259d91e050c57e68ebe995fcb02c06 381 Gene3D G3DSA:1.20.140.10 218 381 1.4E-63 T 28-03-2018 CIG75_RS01620 b3259d91e050c57e68ebe995fcb02c06 381 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 118 1.3E-39 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CIG75_RS01620 b3259d91e050c57e68ebe995fcb02c06 381 SUPERFAMILY SSF56645 1 242 7.59E-94 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CIG75_RS01620 b3259d91e050c57e68ebe995fcb02c06 381 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 216 3.7E-28 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CIG75_RS01620 b3259d91e050c57e68ebe995fcb02c06 381 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 378 4.5E-56 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CIG75_RS01620 b3259d91e050c57e68ebe995fcb02c06 381 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 124 136 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CIG75_RS01620 b3259d91e050c57e68ebe995fcb02c06 381 Gene3D G3DSA:1.10.540.10 1 120 5.8E-42 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CIG75_RS01620 b3259d91e050c57e68ebe995fcb02c06 381 Gene3D G3DSA:2.40.110.10 121 217 6.4E-42 T 28-03-2018 CIG75_RS01620 b3259d91e050c57e68ebe995fcb02c06 381 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 336 355 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CIG75_RS20070 97ebdcaf789bdbafbcfdc8dc65e2d757 502 Pfam PF01336 OB-fold nucleic acid binding domain 68 144 1.0E-13 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CIG75_RS20070 97ebdcaf789bdbafbcfdc8dc65e2d757 502 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 20 502 45.196 T 28-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CIG75_RS20070 97ebdcaf789bdbafbcfdc8dc65e2d757 502 Pfam PF00152 tRNA synthetases class II (D, K and N) 162 499 8.2E-84 T 28-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CIG75_RS20070 97ebdcaf789bdbafbcfdc8dc65e2d757 502 Gene3D G3DSA:3.30.930.10 155 499 1.9E-108 T 28-03-2018 CIG75_RS20070 97ebdcaf789bdbafbcfdc8dc65e2d757 502 SUPERFAMILY SSF50249 12 154 1.23E-41 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CIG75_RS20070 97ebdcaf789bdbafbcfdc8dc65e2d757 502 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 14 501 1.2E-218 T 28-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CIG75_RS20070 97ebdcaf789bdbafbcfdc8dc65e2d757 502 Gene3D G3DSA:2.40.50.140 14 154 7.2E-41 T 28-03-2018 CIG75_RS20070 97ebdcaf789bdbafbcfdc8dc65e2d757 502 PIRSF PIRSF039101 1 502 1.7E-200 T 28-03-2018 IPR034762 Bacterial/eukaryotic lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CIG75_RS20070 97ebdcaf789bdbafbcfdc8dc65e2d757 502 SUPERFAMILY SSF55681 161 500 8.16E-126 T 28-03-2018 CIG75_RS20070 97ebdcaf789bdbafbcfdc8dc65e2d757 502 PRINTS PR00982 Lysyl-tRNA synthetase signature 198 208 2.4E-39 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CIG75_RS20070 97ebdcaf789bdbafbcfdc8dc65e2d757 502 PRINTS PR00982 Lysyl-tRNA synthetase signature 261 278 2.4E-39 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CIG75_RS20070 97ebdcaf789bdbafbcfdc8dc65e2d757 502 PRINTS PR00982 Lysyl-tRNA synthetase signature 214 230 2.4E-39 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CIG75_RS20070 97ebdcaf789bdbafbcfdc8dc65e2d757 502 PRINTS PR00982 Lysyl-tRNA synthetase signature 243 256 2.4E-39 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CIG75_RS20070 97ebdcaf789bdbafbcfdc8dc65e2d757 502 PRINTS PR00982 Lysyl-tRNA synthetase signature 384 400 2.4E-39 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CIG75_RS14925 f8ce7ed28af0bbe2a458c9b84fa56f62 213 Pfam PF07853 Protein of unknown function (DUF1648) 9 57 1.9E-20 T 28-03-2018 IPR012867 Domain of unknown function DUF1648 CIG75_RS14925 f8ce7ed28af0bbe2a458c9b84fa56f62 213 PIRSF PIRSF038959 1 211 1.8E-55 T 28-03-2018 IPR026272 Immunity protein SdpI CIG75_RS14925 f8ce7ed28af0bbe2a458c9b84fa56f62 213 Pfam PF13630 SdpI/YhfL protein family 134 199 1.7E-20 T 28-03-2018 IPR025962 SdpI/YhfL protein family CIG75_RS00510 363412f16f1120950c842ee4f73339f1 448 Gene3D G3DSA:1.10.860.10 1 150 2.0E-49 T 28-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal CIG75_RS00510 363412f16f1120950c842ee4f73339f1 448 Pfam PF00772 DnaB-like helicase N terminal domain 10 111 2.9E-37 T 28-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CIG75_RS00510 363412f16f1120950c842ee4f73339f1 448 Pfam PF03796 DnaB-like helicase C terminal domain 185 440 8.9E-115 T 28-03-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 CIG75_RS00510 363412f16f1120950c842ee4f73339f1 448 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 10 443 6.8E-186 T 28-03-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 CIG75_RS00510 363412f16f1120950c842ee4f73339f1 448 SUPERFAMILY SSF52540 183 434 2.31E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS00510 363412f16f1120950c842ee4f73339f1 448 Gene3D G3DSA:3.40.50.300 167 447 2.9E-73 T 28-03-2018 CIG75_RS00510 363412f16f1120950c842ee4f73339f1 448 SUPERFAMILY SSF48024 8 120 1.44E-39 T 28-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CIG75_RS08265 d75d1be85b7c7c834527941cdb344010 489 Hamap MF_00713 Probable glycine dehydrogenase (decarboxylating) subunit 2 [gcvPB]. 8 487 59.111 T 28-03-2018 IPR023012 Probable glycine dehydrogenase (decarboxylating) subunit 2 GO:0004375|GO:0019464 KEGG: 00260+1.4.4.2 CIG75_RS08265 d75d1be85b7c7c834527941cdb344010 489 Pfam PF02347 Glycine cleavage system P-protein 52 300 9.1E-10 T 28-03-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 CIG75_RS08265 d75d1be85b7c7c834527941cdb344010 489 SUPERFAMILY SSF53383 11 484 5.69E-112 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CIG75_RS08265 d75d1be85b7c7c834527941cdb344010 489 Gene3D G3DSA:3.40.640.10 84 345 1.5E-43 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CIG75_RS08265 d75d1be85b7c7c834527941cdb344010 489 Gene3D G3DSA:3.90.1150.10 346 472 1.4E-43 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CIG75_RS09235 9b5fb95d3aa3f3ff22561faf09222307 719 TIGRFAM TIGR02906 spore_CotS: spore coat protein, CotS family 45 356 1.0E-78 T 28-03-2018 IPR014255 Spore coat protein CotS CIG75_RS09235 9b5fb95d3aa3f3ff22561faf09222307 719 Gene3D G3DSA:3.30.200.20 19 119 9.1E-13 T 28-03-2018 CIG75_RS09235 9b5fb95d3aa3f3ff22561faf09222307 719 Gene3D G3DSA:3.90.1200.10 130 355 1.0E-15 T 28-03-2018 CIG75_RS09235 9b5fb95d3aa3f3ff22561faf09222307 719 SUPERFAMILY SSF56112 32 318 1.05E-30 T 28-03-2018 IPR011009 Protein kinase-like domain CIG75_RS00095 3c657054adbce82d4cc0ef9c9e94f90a 147 Gene3D G3DSA:3.40.140.10 1 147 1.1E-48 T 28-03-2018 CIG75_RS00095 3c657054adbce82d4cc0ef9c9e94f90a 147 Pfam PF14437 MafB19-like deaminase 1 142 4.9E-37 T 28-03-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 CIG75_RS00095 3c657054adbce82d4cc0ef9c9e94f90a 147 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 46 83 - T 28-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 CIG75_RS00095 3c657054adbce82d4cc0ef9c9e94f90a 147 SUPERFAMILY SSF53927 1 142 7.53E-55 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CIG75_RS00095 3c657054adbce82d4cc0ef9c9e94f90a 147 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 1 142 46.123 T 28-03-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 CIG75_RS07780 bc92680b3e5045efe0eef4e2cef7115e 133 Pfam PF16291 Domain of unknown function (DUF4937 2 89 3.2E-29 T 28-03-2018 IPR032555 Domain of unknown function DUF4937 CIG75_RS07780 bc92680b3e5045efe0eef4e2cef7115e 133 SUPERFAMILY SSF54909 1 74 2.68E-7 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CIG75_RS15370 0caa476f82aa22441b601b63383ff806 402 Pfam PF07690 Major Facilitator Superfamily 252 391 5.4E-12 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CIG75_RS15370 0caa476f82aa22441b601b63383ff806 402 Pfam PF07690 Major Facilitator Superfamily 19 250 8.8E-31 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CIG75_RS15370 0caa476f82aa22441b601b63383ff806 402 SUPERFAMILY SSF103473 14 394 8.63E-55 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS15370 0caa476f82aa22441b601b63383ff806 402 Gene3D G3DSA:1.20.1250.20 204 397 1.1E-20 T 28-03-2018 CIG75_RS15370 0caa476f82aa22441b601b63383ff806 402 Gene3D G3DSA:1.20.1250.20 8 203 1.4E-27 T 28-03-2018 CIG75_RS03485 82c4317f28cfdc4741d85346a65d94f3 318 SUPERFAMILY SSF161098 89 297 5.49E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CIG75_RS03485 82c4317f28cfdc4741d85346a65d94f3 318 Gene3D G3DSA:1.10.3720.10 2 300 1.8E-45 T 28-03-2018 CIG75_RS03485 82c4317f28cfdc4741d85346a65d94f3 318 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 311 3.2E-37 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CIG75_RS16640 a8818b0512779696ba4a3a01125bb92a 464 Pfam PF07670 Nucleoside recognition 137 226 2.7E-6 T 28-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 CIG75_RS16640 a8818b0512779696ba4a3a01125bb92a 464 Pfam PF07670 Nucleoside recognition 307 432 4.6E-15 T 28-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 CIG75_RS16640 a8818b0512779696ba4a3a01125bb92a 464 Pfam PF07664 Ferrous iron transport protein B C terminus 249 298 3.1E-14 T 28-03-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 CIG75_RS17205 a10cf4e48452dcc8c11c614627365bfc 143 SUPERFAMILY SSF47240 6 142 1.46E-38 T 28-03-2018 IPR009078 Ferritin-like superfamily CIG75_RS17205 a10cf4e48452dcc8c11c614627365bfc 143 Gene3D G3DSA:1.20.1260.10 88 143 9.6E-12 T 28-03-2018 IPR012347 Ferritin-related CIG75_RS17205 a10cf4e48452dcc8c11c614627365bfc 143 Gene3D G3DSA:1.20.1260.10 2 87 7.8E-19 T 28-03-2018 IPR012347 Ferritin-related CIG75_RS17205 a10cf4e48452dcc8c11c614627365bfc 143 Pfam PF02915 Rubrerythrin 12 138 2.1E-25 T 28-03-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 CIG75_RS12355 1574c6939141a9bd8bc1eebbae87f3ad 78 Hamap MF_01217 Acyl carrier protein [acpP]. 4 78 22.623 T 28-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 CIG75_RS12355 1574c6939141a9bd8bc1eebbae87f3ad 78 Gene3D G3DSA:1.10.1200.10 2 78 1.5E-25 T 28-03-2018 CIG75_RS12355 1574c6939141a9bd8bc1eebbae87f3ad 78 ProSitePatterns PS00012 Phosphopantetheine attachment site. 33 48 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CIG75_RS12355 1574c6939141a9bd8bc1eebbae87f3ad 78 SUPERFAMILY SSF47336 3 77 2.88E-23 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS12355 1574c6939141a9bd8bc1eebbae87f3ad 78 Pfam PF00550 Phosphopantetheine attachment site 8 74 2.1E-16 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS12355 1574c6939141a9bd8bc1eebbae87f3ad 78 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 3 78 1.0E-33 T 28-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 CIG75_RS17760 0bcfc56db0946909b7cd6f7cd7f8b428 84 ProDom PD058324 UPF0349 LMO2392 BLI03401/BL03152 SA0800 SAR0901 LIN2491 SERP0525 GK2958 BT9727_4649 BC4937 8 67 8.0E-7 T 28-03-2018 CIG75_RS17760 0bcfc56db0946909b7cd6f7cd7f8b428 84 Pfam PF07293 Protein of unknown function (DUF1450) 8 77 3.6E-14 T 28-03-2018 IPR009910 Protein of unknown function DUF1450 CIG75_RS04095 1e5ddd7d05b36999f4ffc08ed30d0bd2 607 SUPERFAMILY SSF51730 310 595 5.69E-71 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like CIG75_RS04095 1e5ddd7d05b36999f4ffc08ed30d0bd2 607 Gene3D G3DSA:3.20.20.330 1 307 1.1E-74 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CIG75_RS04095 1e5ddd7d05b36999f4ffc08ed30d0bd2 607 Pfam PF02574 Homocysteine S-methyltransferase 18 271 9.9E-51 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CIG75_RS04095 1e5ddd7d05b36999f4ffc08ed30d0bd2 607 Pfam PF02219 Methylenetetrahydrofolate reductase 310 571 1.7E-33 T 28-03-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CIG75_RS04095 1e5ddd7d05b36999f4ffc08ed30d0bd2 607 Gene3D G3DSA:3.20.20.220 308 606 1.2E-67 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like CIG75_RS04095 1e5ddd7d05b36999f4ffc08ed30d0bd2 607 SUPERFAMILY SSF82282 1 357 1.96E-85 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CIG75_RS11755 efe0f94faf248db256f792403b27395f 243 SUPERFAMILY SSF88713 49 238 1.36E-25 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CIG75_RS11755 efe0f94faf248db256f792403b27395f 243 Pfam PF01522 Polysaccharide deacetylase 55 168 4.0E-19 T 28-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CIG75_RS11755 efe0f94faf248db256f792403b27395f 243 Gene3D G3DSA:3.20.20.370 48 243 8.7E-24 T 28-03-2018 CIG75_RS16895 39122dd6d05d53966b3b6f351d8750ad 177 Pfam PF02283 Cobinamide kinase / cobinamide phosphate guanyltransferase 4 177 5.5E-52 T 28-03-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CIG75_RS16895 39122dd6d05d53966b3b6f351d8750ad 177 Gene3D G3DSA:3.40.50.300 3 177 1.1E-52 T 28-03-2018 CIG75_RS16895 39122dd6d05d53966b3b6f351d8750ad 177 SUPERFAMILY SSF52540 4 176 1.44E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS16895 39122dd6d05d53966b3b6f351d8750ad 177 PIRSF PIRSF006135 2 177 3.0E-49 T 28-03-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CIG75_RS10065 0a51671c04f3f656f6d383a259ba5ee4 183 Gene3D G3DSA:1.10.1740.10 1 90 1.1E-21 T 28-03-2018 CIG75_RS10065 0a51671c04f3f656f6d383a259ba5ee4 183 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 43 74 - T 28-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS10065 0a51671c04f3f656f6d383a259ba5ee4 183 Pfam PF04542 Sigma-70 region 2 24 87 3.4E-13 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS10065 0a51671c04f3f656f6d383a259ba5ee4 183 SUPERFAMILY SSF88946 2 101 2.08E-22 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS10065 0a51671c04f3f656f6d383a259ba5ee4 183 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 17 170 6.2E-24 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS10065 0a51671c04f3f656f6d383a259ba5ee4 183 Pfam PF08281 Sigma-70, region 4 114 167 3.1E-14 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS10065 0a51671c04f3f656f6d383a259ba5ee4 183 SUPERFAMILY SSF88659 105 172 4.49E-15 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS10065 0a51671c04f3f656f6d383a259ba5ee4 183 Gene3D G3DSA:1.10.10.10 91 174 2.9E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS12600 df4ee750bd52efd00122256541831b8b 250 SUPERFAMILY SSF53474 3 247 4.61E-39 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS12600 df4ee750bd52efd00122256541831b8b 250 Gene3D G3DSA:3.40.50.1820 2 250 7.8E-27 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS12600 df4ee750bd52efd00122256541831b8b 250 Pfam PF00756 Putative esterase 22 241 1.4E-37 T 28-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 CIG75_RS03050 3ba06f778e6b6d7899f573f79ef3c4e1 104 SUPERFAMILY SSF103481 4 102 1.22E-14 T 28-03-2018 CIG75_RS03050 3ba06f778e6b6d7899f573f79ef3c4e1 104 Pfam PF00893 Small Multidrug Resistance protein 1 93 4.8E-24 T 28-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 CIG75_RS20120 84055d210ef534eecaecf0d5978a186d 350 Pfam PF14398 YheC/D like ATP-grasp 104 348 7.8E-53 T 28-03-2018 IPR026838 Endospore coat-associated protein YheC/D CIG75_RS20120 84055d210ef534eecaecf0d5978a186d 350 Gene3D G3DSA:3.30.1490.20 134 200 1.1E-9 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CIG75_RS20120 84055d210ef534eecaecf0d5978a186d 350 Gene3D G3DSA:3.30.470.20 201 334 1.1E-14 T 28-03-2018 CIG75_RS20120 84055d210ef534eecaecf0d5978a186d 350 SUPERFAMILY SSF56059 124 332 3.14E-19 T 28-03-2018 CIG75_RS15385 b150c96ef095975cd66f2e7749b8847a 212 Pfam PF13529 Peptidase_C39 like family 57 191 3.7E-9 T 28-03-2018 CIG75_RS15385 b150c96ef095975cd66f2e7749b8847a 212 Gene3D G3DSA:3.90.70.10 78 206 1.1E-13 T 28-03-2018 CIG75_RS12370 6e299098a14c8f4df7895e0ec826c627 328 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 4 328 72.554 T 28-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CIG75_RS12370 6e299098a14c8f4df7895e0ec826c627 328 SUPERFAMILY SSF53901 6 328 6.35E-80 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS12370 6e299098a14c8f4df7895e0ec826c627 328 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 109 187 3.0E-31 T 28-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CIG75_RS12370 6e299098a14c8f4df7895e0ec826c627 328 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 6 328 2.3E-133 T 28-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CIG75_RS12370 6e299098a14c8f4df7895e0ec826c627 328 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 239 328 1.1E-39 T 28-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CIG75_RS12370 6e299098a14c8f4df7895e0ec826c627 328 Gene3D G3DSA:3.40.47.10 163 328 3.3E-49 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS12370 6e299098a14c8f4df7895e0ec826c627 328 Gene3D G3DSA:3.40.47.10 1 162 3.1E-42 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS05165 4434af812e9a3d7b1cb80665bb7c0b50 159 SUPERFAMILY SSF47240 37 152 3.75E-15 T 28-03-2018 IPR009078 Ferritin-like superfamily CIG75_RS05165 4434af812e9a3d7b1cb80665bb7c0b50 159 Gene3D G3DSA:1.20.1260.10 25 96 1.9E-6 T 28-03-2018 IPR012347 Ferritin-related CIG75_RS05165 4434af812e9a3d7b1cb80665bb7c0b50 159 Gene3D G3DSA:1.20.1260.10 97 158 3.5E-7 T 28-03-2018 IPR012347 Ferritin-related CIG75_RS04255 2037690bcf1a77b90a49e7bd25193ed7 480 Gene3D G3DSA:3.40.50.300 1 353 2.0E-25 T 28-03-2018 CIG75_RS04255 2037690bcf1a77b90a49e7bd25193ed7 480 SUPERFAMILY SSF52540 1 199 5.94E-26 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS04255 2037690bcf1a77b90a49e7bd25193ed7 480 Pfam PF00350 Dynamin family 1 143 7.7E-20 T 28-03-2018 IPR022812 Dynamin superfamily CIG75_RS08195 f6dc60233cc2ce4d5c5535e2be30d290 112 Gene3D G3DSA:3.30.1300.30 21 110 0.0019 T 28-03-2018 CIG75_RS07105 78168a581159b6f8aaacbb2fb70a13de 173 Pfam PF09419 Mitochondrial PGP phosphatase 4 136 8.0E-11 T 28-03-2018 IPR027706 Mitochondrial PGP phosphatase KEGG: 00564+3.1.3.27|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 CIG75_RS07105 78168a581159b6f8aaacbb2fb70a13de 173 Gene3D G3DSA:3.40.50.1000 10 150 6.3E-21 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS07105 78168a581159b6f8aaacbb2fb70a13de 173 TIGRFAM TIGR01668 YqeG_hyp_ppase: HAD phosphatase, family IIIA 5 166 1.1E-47 T 28-03-2018 IPR010021 HAD-superfamily phosphatase, YqeG-like CIG75_RS07105 78168a581159b6f8aaacbb2fb70a13de 173 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 20 130 4.4E-6 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CIG75_RS07105 78168a581159b6f8aaacbb2fb70a13de 173 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 28 138 7.2E-19 T 28-03-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 CIG75_RS07105 78168a581159b6f8aaacbb2fb70a13de 173 SUPERFAMILY SSF56784 7 150 7.31E-24 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS06335 d79b06a4e031ae5835ceedff524045be 361 SUPERFAMILY SSF109604 129 295 9.95E-31 T 28-03-2018 CIG75_RS06335 d79b06a4e031ae5835ceedff524045be 361 SMART SM00471 131 267 1.7E-7 T 28-03-2018 IPR003607 HD/PDEase domain CIG75_RS06335 d79b06a4e031ae5835ceedff524045be 361 Pfam PF01966 HD domain 136 257 1.6E-16 T 28-03-2018 IPR006674 HD domain CIG75_RS06335 d79b06a4e031ae5835ceedff524045be 361 Gene3D G3DSA:1.10.3210.10 74 300 3.4E-39 T 28-03-2018 CIG75_RS06335 d79b06a4e031ae5835ceedff524045be 361 TIGRFAM TIGR00277 HDIG: HDIG domain 135 226 1.7E-7 T 28-03-2018 IPR006675 HDIG domain CIG75_RS15440 f87f2965b895c7a10d5a3a437b4bee2d 240 SMART SM00382 26 213 4.6E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS15440 f87f2965b895c7a10d5a3a437b4bee2d 240 PIRSF PIRSF039085 1 240 2.4E-111 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CIG75_RS15440 f87f2965b895c7a10d5a3a437b4bee2d 240 Gene3D G3DSA:3.40.50.300 1 240 9.2E-78 T 28-03-2018 CIG75_RS15440 f87f2965b895c7a10d5a3a437b4bee2d 240 Pfam PF00005 ABC transporter 17 165 1.4E-37 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS15440 f87f2965b895c7a10d5a3a437b4bee2d 240 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS15440 f87f2965b895c7a10d5a3a437b4bee2d 240 SUPERFAMILY SSF52540 1 235 1.46E-80 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS20330 5ad8328e52516f7ed75b580e6b28141a 276 TIGRFAM TIGR02069 cyanophycinase: cyanophycinase 8 255 2.8E-95 T 28-03-2018 IPR011811 Peptidase S51, cyanophycinase GO:0016787|GO:0044260 MetaCyc: PWY-7052 CIG75_RS20330 5ad8328e52516f7ed75b580e6b28141a 276 PIRSF PIRSF032067 3 274 1.9E-70 T 28-03-2018 IPR011811 Peptidase S51, cyanophycinase GO:0016787|GO:0044260 MetaCyc: PWY-7052 CIG75_RS20330 5ad8328e52516f7ed75b580e6b28141a 276 Gene3D G3DSA:3.40.50.880 3 268 2.0E-73 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CIG75_RS20330 5ad8328e52516f7ed75b580e6b28141a 276 Pfam PF03575 Peptidase family S51 8 213 2.1E-24 T 28-03-2018 IPR005320 Peptidase S51 GO:0006508|GO:0008236 CIG75_RS20330 5ad8328e52516f7ed75b580e6b28141a 276 SUPERFAMILY SSF52317 7 221 1.1E-27 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CIG75_RS06100 4ed469b13a3b4123bc744d450eb9496d 248 SMART SM01001 113 245 6.3E-32 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CIG75_RS06100 4ed469b13a3b4123bc744d450eb9496d 248 SUPERFAMILY SSF52255 113 241 7.59E-26 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CIG75_RS06100 4ed469b13a3b4123bc744d450eb9496d 248 Pfam PF00731 AIR carboxylase 114 239 1.2E-12 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CIG75_RS06100 4ed469b13a3b4123bc744d450eb9496d 248 Gene3D G3DSA:3.40.50.7700 106 244 1.2E-33 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CIG75_RS12745 7d92a0a595524ba6de6578c82c7886de 197 Gene3D G3DSA:3.10.350.10 140 197 1.2E-14 T 28-03-2018 CIG75_RS12745 7d92a0a595524ba6de6578c82c7886de 197 Pfam PF01476 LysM domain 147 196 4.8E-7 T 28-03-2018 IPR018392 LysM domain CIG75_RS12745 7d92a0a595524ba6de6578c82c7886de 197 SMART SM00257 146 196 5.3E-8 T 28-03-2018 IPR018392 LysM domain CIG75_RS12745 7d92a0a595524ba6de6578c82c7886de 197 SUPERFAMILY SSF54106 145 196 2.22E-6 T 28-03-2018 IPR018392 LysM domain CIG75_RS04760 7957a1b04358256febf02f2c68a7492a 337 Pfam PF00395 S-layer homology domain 282 324 5.0E-6 T 28-03-2018 IPR001119 S-layer homology domain CIG75_RS04760 7957a1b04358256febf02f2c68a7492a 337 Pfam PF00395 S-layer homology domain 159 201 1.1E-8 T 28-03-2018 IPR001119 S-layer homology domain CIG75_RS04760 7957a1b04358256febf02f2c68a7492a 337 Pfam PF00395 S-layer homology domain 218 260 3.1E-7 T 28-03-2018 IPR001119 S-layer homology domain CIG75_RS04760 7957a1b04358256febf02f2c68a7492a 337 Gene3D G3DSA:2.60.120.430 2 154 2.5E-21 T 28-03-2018 CIG75_RS19735 38f3e91438afb76815b71f272c1372f9 207 Gene3D G3DSA:4.10.960.10 55 161 8.3E-33 T 28-03-2018 CIG75_RS19735 38f3e91438afb76815b71f272c1372f9 207 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 3 200 7.3E-85 T 28-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS19735 38f3e91438afb76815b71f272c1372f9 207 ProSitePatterns PS00474 Ribosomal protein L3 signature. 99 122 - T 28-03-2018 IPR019926 Ribosomal protein L3, conserved site CIG75_RS19735 38f3e91438afb76815b71f272c1372f9 207 Pfam PF00297 Ribosomal protein L3 92 203 1.1E-17 T 28-03-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS19735 38f3e91438afb76815b71f272c1372f9 207 SUPERFAMILY SSF50447 1 205 7.06E-80 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CIG75_RS19735 38f3e91438afb76815b71f272c1372f9 207 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 1 203 39.485 T 28-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS14335 9649238ed30cb884ac0d93abd6cedca8 132 SUPERFAMILY SSF55961 3 132 1.95E-33 T 28-03-2018 CIG75_RS14335 9649238ed30cb884ac0d93abd6cedca8 132 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 13 131 7.1E-22 T 28-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CIG75_RS14335 9649238ed30cb884ac0d93abd6cedca8 132 Gene3D G3DSA:3.30.530.20 1 132 9.9E-23 T 28-03-2018 IPR023393 START-like domain CIG75_RS03635 8bbc25c13727050d5601dd545d0b6dff 434 SUPERFAMILY SSF51556 59 356 1.08E-94 T 28-03-2018 IPR032466 Metal-dependent hydrolase CIG75_RS03635 8bbc25c13727050d5601dd545d0b6dff 434 SUPERFAMILY SSF51338 1 59 1.76E-34 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CIG75_RS03635 8bbc25c13727050d5601dd545d0b6dff 434 SUPERFAMILY SSF51338 356 431 1.76E-34 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CIG75_RS03635 8bbc25c13727050d5601dd545d0b6dff 434 Hamap MF_01281 5'-deoxyadenosine deaminase [dadD]. 2 431 45.012 T 28-03-2018 IPR023512 Deaminase MtaD/DadD GO:0019239 CIG75_RS03635 8bbc25c13727050d5601dd545d0b6dff 434 Gene3D G3DSA:3.20.20.140 74 340 1.7E-57 T 28-03-2018 CIG75_RS03635 8bbc25c13727050d5601dd545d0b6dff 434 Pfam PF01979 Amidohydrolase family 56 404 3.7E-68 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CIG75_RS03635 8bbc25c13727050d5601dd545d0b6dff 434 Gene3D G3DSA:2.30.40.10 2 73 7.0E-19 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CIG75_RS03635 8bbc25c13727050d5601dd545d0b6dff 434 Gene3D G3DSA:3.20.20.140 341 388 0.0014 T 28-03-2018 CIG75_RS13290 061f934e0a6e1b8314a4b450b7079bf5 483 Pfam PF07690 Major Facilitator Superfamily 17 406 8.5E-42 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CIG75_RS13290 061f934e0a6e1b8314a4b450b7079bf5 483 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 14 415 5.6E-87 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CIG75_RS13290 061f934e0a6e1b8314a4b450b7079bf5 483 Gene3D G3DSA:1.20.1250.20 2 195 2.4E-31 T 28-03-2018 CIG75_RS13290 061f934e0a6e1b8314a4b450b7079bf5 483 SUPERFAMILY SSF103473 245 459 3.66E-61 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS13290 061f934e0a6e1b8314a4b450b7079bf5 483 SUPERFAMILY SSF103473 8 194 3.66E-61 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS13290 061f934e0a6e1b8314a4b450b7079bf5 483 Gene3D G3DSA:1.20.1250.20 249 471 5.4E-23 T 28-03-2018 CIG75_RS01665 087c04ac9b45cca20e42b5b867fc3382 155 Pfam PF12821 Threonine/Serine exporter, ThrE 16 139 1.1E-26 T 28-03-2018 IPR024528 Threonine/Serine exporter, ThrE CIG75_RS15730 e7acbf0f5dc0cb102833b77605e5c490 101 SMART SM00450 8 101 3.2E-14 T 28-03-2018 IPR001763 Rhodanese-like domain CIG75_RS15730 e7acbf0f5dc0cb102833b77605e5c490 101 Pfam PF00581 Rhodanese-like domain 11 97 1.7E-15 T 28-03-2018 IPR001763 Rhodanese-like domain CIG75_RS15730 e7acbf0f5dc0cb102833b77605e5c490 101 SUPERFAMILY SSF52821 3 99 2.36E-27 T 28-03-2018 IPR001763 Rhodanese-like domain CIG75_RS15730 e7acbf0f5dc0cb102833b77605e5c490 101 Gene3D G3DSA:3.40.250.10 1 100 4.5E-25 T 28-03-2018 IPR001763 Rhodanese-like domain CIG75_RS11370 d9aef9fbfd645c518e4674304373f426 423 TIGRFAM TIGR02871 spore_ylbJ: sporulation integral membrane protein YlbJ 11 386 4.6E-104 T 28-03-2018 IPR014226 Sporulation integral membrane protein YlbJ CIG75_RS14420 fdf6f3155886747b545d61aa5e770c0e 96 Gene3D G3DSA:1.20.5.170 13 76 4.0E-4 T 28-03-2018 CIG75_RS14420 fdf6f3155886747b545d61aa5e770c0e 96 Pfam PF10737 Spore germination protein GerPC 38 92 2.4E-7 T 28-03-2018 IPR019673 Spore germination protein GerPC CIG75_RS09425 ebcf2c85fafba78b5d0690c080be773f 492 SUPERFAMILY SSF52540 19 237 2.39E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS09425 ebcf2c85fafba78b5d0690c080be773f 492 PIRSF PIRSF007466 1 492 1.3E-259 T 28-03-2018 IPR014201 Sporulation stage IV, protein A GO:0005524|GO:0016887|GO:0043934 KEGG: 00230+3.6.1.3 CIG75_RS09425 ebcf2c85fafba78b5d0690c080be773f 492 Pfam PF09547 Stage IV sporulation protein A (spore_IV_A) 2 492 1.8E-229 T 28-03-2018 IPR014201 Sporulation stage IV, protein A GO:0005524|GO:0016887|GO:0043934 KEGG: 00230+3.6.1.3 CIG75_RS09425 ebcf2c85fafba78b5d0690c080be773f 492 Gene3D G3DSA:3.40.50.300 10 483 2.2E-13 T 28-03-2018 CIG75_RS09425 ebcf2c85fafba78b5d0690c080be773f 492 TIGRFAM TIGR02836 spore_IV_A: stage IV sporulation protein A 1 492 4.6E-258 T 28-03-2018 IPR014201 Sporulation stage IV, protein A GO:0005524|GO:0016887|GO:0043934 KEGG: 00230+3.6.1.3 CIG75_RS14035 a4dc3cca2fa25077147148ed6744b4ac 64 Gene3D G3DSA:1.10.287.540 4 56 1.7E-25 T 28-03-2018 CIG75_RS14035 a4dc3cca2fa25077147148ed6744b4ac 64 Hamap MF_01103 UPF0291 protein . 2 63 14.573 T 28-03-2018 IPR009242 Protein of unknown function DUF896 CIG75_RS14035 a4dc3cca2fa25077147148ed6744b4ac 64 Pfam PF05979 Bacterial protein of unknown function (DUF896) 5 58 2.8E-23 T 28-03-2018 IPR009242 Protein of unknown function DUF896 CIG75_RS14035 a4dc3cca2fa25077147148ed6744b4ac 64 SUPERFAMILY SSF158221 1 42 1.01E-13 T 28-03-2018 CIG75_RS13545 4527ff4c6d6f9621b767367881de5ef1 116 Gene3D G3DSA:1.10.10.10 1 110 5.3E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS13545 4527ff4c6d6f9621b767367881de5ef1 116 SUPERFAMILY SSF46785 4 106 1.96E-36 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS13545 4527ff4c6d6f9621b767367881de5ef1 116 Pfam PF01638 HxlR-like helix-turn-helix 17 103 7.1E-33 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type CIG75_RS02005 c1b653bea0cb41c480df6e54cc00924c 505 TIGRFAM TIGR01770 NDH_I_N: proton-translocating NADH-quinone oxidoreductase, chain N 16 493 5.4E-114 T 28-03-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 CIG75_RS02005 c1b653bea0cb41c480df6e54cc00924c 505 Pfam PF00361 Proton-conducting membrane transporter 139 440 1.4E-66 T 28-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CIG75_RS02005 c1b653bea0cb41c480df6e54cc00924c 505 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 14 494 17.277 T 28-03-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 CIG75_RS02185 8068329b96c43695317a730b56be160e 242 Hamap MF_02070 N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase. 2 238 55.27 T 28-03-2018 IPR034714 N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase GO:0047244 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7815|MetaCyc: PWY-7816|MetaCyc: PWY-7819 CIG75_RS02185 8068329b96c43695317a730b56be160e 242 Pfam PF03808 Glycosyl transferase WecB/TagA/CpsF family 58 223 7.2E-58 T 28-03-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 CIG75_RS02185 8068329b96c43695317a730b56be160e 242 TIGRFAM TIGR00696 wecG_tagA_cpsF: glycosyltransferase, WecB/TagA/CpsF family 54 229 4.9E-54 T 28-03-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 CIG75_RS11375 18606d07ad0f42b6c34b0a0857ab0acc 261 Pfam PF02673 Bacitracin resistance protein BacA 6 246 3.2E-75 T 28-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CIG75_RS11375 18606d07ad0f42b6c34b0a0857ab0acc 261 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 1 252 16.623 T 28-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CIG75_RS14915 6535707b7245f5b47a4544533e76b967 312 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 9 283 2.4E-74 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CIG75_RS14915 6535707b7245f5b47a4544533e76b967 312 Gene3D G3DSA:1.20.1510.10 7 201 2.9E-46 T 28-03-2018 CIG75_RS14915 6535707b7245f5b47a4544533e76b967 312 SUPERFAMILY SSF160240 208 280 2.75E-9 T 28-03-2018 CIG75_RS14915 6535707b7245f5b47a4544533e76b967 312 Pfam PF01545 Cation efflux family 12 201 2.5E-41 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CIG75_RS14915 6535707b7245f5b47a4544533e76b967 312 Gene3D G3DSA:3.30.70.1350 204 285 2.4E-12 T 28-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CIG75_RS14915 6535707b7245f5b47a4544533e76b967 312 SUPERFAMILY SSF161111 9 202 1.2E-46 T 28-03-2018 CIG75_RS11000 109f537a4e588e1cc298cedc08efbacf 403 Pfam PF14028 Lantibiotic biosynthesis dehydratase C-term 17 368 9.5E-36 T 28-03-2018 IPR023809 Thiopeptide-type bacteriocin biosynthesis domain CIG75_RS13765 74e713069f67798ef31c6fd237d476b7 198 SUPERFAMILY SSF89260 82 192 9.55E-6 T 28-03-2018 CIG75_RS13765 74e713069f67798ef31c6fd237d476b7 198 Gene3D G3DSA:2.60.120.380 73 197 2.6E-7 T 28-03-2018 CIG75_RS01385 2591861bc47b4556afbca301b1da8f3c 558 PIRSF PIRSF005690 50 535 1.2E-181 T 28-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 CIG75_RS01385 2591861bc47b4556afbca301b1da8f3c 558 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 64 520 4.5E-194 T 28-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 CIG75_RS08850 c2094e0a5cc30344a0f9d47f4699acf3 498 Pfam PF05140 ResB-like family 28 457 1.7E-83 T 28-03-2018 IPR007816 ResB-like domain CIG75_RS14680 c56b25624678e2c5c0a709a9fce3fdb6 139 Pfam PF00892 EamA-like transporter family 2 137 8.4E-20 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CIG75_RS14680 c56b25624678e2c5c0a709a9fce3fdb6 139 SUPERFAMILY SSF103481 58 137 1.57E-13 T 28-03-2018 CIG75_RS07480 a7fbb01dff714eb8dad07a013cb0167f 64 Pfam PF01361 Tautomerase enzyme 2 58 8.8E-20 T 28-03-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 CIG75_RS07480 a7fbb01dff714eb8dad07a013cb0167f 64 SUPERFAMILY SSF55331 2 62 1.31E-18 T 28-03-2018 IPR014347 Tautomerase/MIF superfamily CIG75_RS07480 a7fbb01dff714eb8dad07a013cb0167f 64 Gene3D G3DSA:3.30.429.10 1 60 2.1E-19 T 28-03-2018 CIG75_RS07480 a7fbb01dff714eb8dad07a013cb0167f 64 TIGRFAM TIGR00013 taut: 4-oxalocrotonate tautomerase family enzyme 1 60 1.7E-19 T 28-03-2018 IPR018191 4-oxalocrotonate tautomerase, Pseudomonas-type GO:0006725|GO:0016853 CIG75_RS18860 cde4ff8ca79fae5d79fd4cdfb993eaca 408 SUPERFAMILY SSF56266 19 404 3.92E-136 T 28-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CIG75_RS18860 cde4ff8ca79fae5d79fd4cdfb993eaca 408 Pfam PF01960 ArgJ family 24 408 6.1E-150 T 28-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CIG75_RS18860 cde4ff8ca79fae5d79fd4cdfb993eaca 408 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 408 151.158 T 28-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CIG75_RS18860 cde4ff8ca79fae5d79fd4cdfb993eaca 408 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 13 408 6.6E-154 T 28-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CIG75_RS18860 cde4ff8ca79fae5d79fd4cdfb993eaca 408 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 37 408 2.0E-114 T 28-03-2018 CIG75_RS18860 cde4ff8ca79fae5d79fd4cdfb993eaca 408 Gene3D G3DSA:3.60.70.12 11 281 2.1E-104 T 28-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CIG75_RS01040 9729a38770e0e315f8055192c1408480 321 Gene3D G3DSA:3.40.50.1980 30 157 2.8E-30 T 28-03-2018 CIG75_RS01040 9729a38770e0e315f8055192c1408480 321 Pfam PF01497 Periplasmic binding protein 63 297 4.9E-36 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CIG75_RS01040 9729a38770e0e315f8055192c1408480 321 Gene3D G3DSA:3.40.50.1980 158 321 4.7E-35 T 28-03-2018 CIG75_RS01040 9729a38770e0e315f8055192c1408480 321 SUPERFAMILY SSF53807 45 313 3.92E-73 T 28-03-2018 CIG75_RS15595 431a32539db313871b90117ce8ba3435 75 Pfam PF11007 Spore coat associated protein JA (CotJA) 28 63 1.0E-8 T 28-03-2018 IPR020256 Spore coat protein CotJA CIG75_RS15595 431a32539db313871b90117ce8ba3435 75 ProDom PD059966 COTJA SPORE PROTEIN-RELATED COAT-ASSOCIATED COTJAA JA 6 63 4.0E-14 T 28-03-2018 IPR020256 Spore coat protein CotJA CIG75_RS18205 5806b1a8e3b083eef762a2c2b4666706 410 SUPERFAMILY SSF103473 7 400 3.01E-28 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS18205 5806b1a8e3b083eef762a2c2b4666706 410 Gene3D G3DSA:1.20.1250.20 210 408 1.1E-14 T 28-03-2018 CIG75_RS18205 5806b1a8e3b083eef762a2c2b4666706 410 Pfam PF07690 Major Facilitator Superfamily 34 345 2.2E-10 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CIG75_RS18205 5806b1a8e3b083eef762a2c2b4666706 410 Gene3D G3DSA:1.20.1250.20 5 199 2.6E-8 T 28-03-2018 CIG75_RS17250 3ec580a690affccdb76210880801af89 684 Gene3D G3DSA:2.60.40.1730 283 643 2.9E-4 T 28-03-2018 CIG75_RS10505 c63258ab7357af375f1f2f1dc6c8a8c4 231 Gene3D G3DSA:2.60.120.10 13 132 5.7E-47 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CIG75_RS10505 c63258ab7357af375f1f2f1dc6c8a8c4 231 Gene3D G3DSA:2.60.120.10 133 231 1.2E-19 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CIG75_RS10505 c63258ab7357af375f1f2f1dc6c8a8c4 231 Pfam PF02678 Pirin 12 120 3.5E-36 T 28-03-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 CIG75_RS10505 c63258ab7357af375f1f2f1dc6c8a8c4 231 PIRSF PIRSF006232 1 230 2.4E-54 T 28-03-2018 IPR012093 Pirin Reactome: R-HSA-8935690 CIG75_RS10505 c63258ab7357af375f1f2f1dc6c8a8c4 231 SUPERFAMILY SSF51182 4 230 6.51E-70 T 28-03-2018 IPR011051 RmlC-like cupin domain CIG75_RS09805 2958931e3f0dd49f8d1721186614f7b9 808 SUPERFAMILY SSF56235 44 805 6.95E-218 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CIG75_RS09805 2958931e3f0dd49f8d1721186614f7b9 808 Pfam PF01804 Penicillin amidase 46 794 2.1E-218 T 28-03-2018 IPR002692 Penicillin/GL-7-ACA/AHL/aculeacin-A acylase GO:0016787|GO:0017000 CIG75_RS09805 2958931e3f0dd49f8d1721186614f7b9 808 Gene3D G3DSA:3.60.20.10 262 664 2.0E-106 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CIG75_RS09805 2958931e3f0dd49f8d1721186614f7b9 808 Gene3D G3DSA:3.60.20.10 665 797 1.9E-24 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CIG75_RS09805 2958931e3f0dd49f8d1721186614f7b9 808 PIRSF PIRSF001227 5 805 1.9E-201 T 28-03-2018 IPR014395 Penicillin/GL-7-ACA/AHL acylase GO:0016811 CIG75_RS09805 2958931e3f0dd49f8d1721186614f7b9 808 Gene3D G3DSA:1.10.439.10 34 198 4.1E-52 T 28-03-2018 IPR023343 Penicillin amidase type, domain1 GO:0016811 CIG75_RS10080 38331a742c0cc482bf8cad4424a4d77d 430 Gene3D G3DSA:3.40.640.10 68 281 3.7E-33 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CIG75_RS10080 38331a742c0cc482bf8cad4424a4d77d 430 Pfam PF06838 Methionine gamma-lyase 23 422 1.5E-195 T 28-03-2018 IPR009651 Putative methionine gamma-lyase CIG75_RS10080 38331a742c0cc482bf8cad4424a4d77d 430 SUPERFAMILY SSF53383 30 378 3.93E-43 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CIG75_RS05745 3d51b124efbeee52d5194e7d3f986538 94 Pfam PF13045 Protein of unknown function (DUF3905) 29 67 1.1E-9 T 28-03-2018 IPR024999 Protein of unknown function DUF3905 CIG75_RS09470 b000ebc5adcd49b20a2f5a549a494adf 99 Pfam PF00589 Phage integrase family 19 70 5.2E-13 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CIG75_RS09470 b000ebc5adcd49b20a2f5a549a494adf 99 SUPERFAMILY SSF56349 17 79 3.83E-17 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CIG75_RS09470 b000ebc5adcd49b20a2f5a549a494adf 99 Gene3D G3DSA:1.10.443.10 1 88 5.4E-15 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CIG75_RS16035 0e0420a1cdf7111c49dc21a638a97273 55 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 5 47 2.5E-19 T 28-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 CIG75_RS16035 0e0420a1cdf7111c49dc21a638a97273 55 Pfam PF02416 mttA/Hcf106 family 5 54 2.3E-19 T 28-03-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 CIG75_RS16035 0e0420a1cdf7111c49dc21a638a97273 55 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 2 55 16.599 T 28-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 CIG75_RS16035 0e0420a1cdf7111c49dc21a638a97273 55 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 22 41 5.6E-6 T 28-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 CIG75_RS16035 0e0420a1cdf7111c49dc21a638a97273 55 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 2 22 5.6E-6 T 28-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 CIG75_RS06310 657febfe1bb2fede258aaa88091b385c 167 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 139 151 1.4E-37 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CIG75_RS06310 657febfe1bb2fede258aaa88091b385c 167 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 4 17 1.4E-37 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CIG75_RS06310 657febfe1bb2fede258aaa88091b385c 167 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 107 126 1.4E-37 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CIG75_RS06310 657febfe1bb2fede258aaa88091b385c 167 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 61 77 1.4E-37 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CIG75_RS06310 657febfe1bb2fede258aaa88091b385c 167 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 83 99 1.4E-37 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CIG75_RS06310 657febfe1bb2fede258aaa88091b385c 167 Gene3D G3DSA:3.30.420.10 1 159 5.8E-50 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CIG75_RS06310 657febfe1bb2fede258aaa88091b385c 167 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 3 151 8.2E-56 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CIG75_RS06310 657febfe1bb2fede258aaa88091b385c 167 SUPERFAMILY SSF53098 1 156 2.85E-50 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CIG75_RS06310 657febfe1bb2fede258aaa88091b385c 167 ProSitePatterns PS01321 Crossover junction endodeoxyribonuclease ruvC signature. 113 148 - T 28-03-2018 IPR020563 Crossover junction endodeoxyribonuclease RuvC, magnesium-binding site GO:0008821 CIG75_RS06310 657febfe1bb2fede258aaa88091b385c 167 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 1 154 48.609 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CIG75_RS06310 657febfe1bb2fede258aaa88091b385c 167 TIGRFAM TIGR00228 ruvC: crossover junction endodeoxyribonuclease RuvC 3 154 5.0E-48 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CIG75_RS12215 c3908e41b29cda1cef0d683c8bcfdc75 302 PIRSF PIRSF006230 1 283 2.8E-99 T 28-03-2018 IPR016478 GTPase, MTG1 CIG75_RS12215 c3908e41b29cda1cef0d683c8bcfdc75 302 Gene3D G3DSA:3.40.50.300 12 179 7.5E-33 T 28-03-2018 CIG75_RS12215 c3908e41b29cda1cef0d683c8bcfdc75 302 Gene3D G3DSA:1.10.1580.10 180 272 4.9E-23 T 28-03-2018 IPR023179 GTP-binding protein, orthogonal bundle domain CIG75_RS12215 c3908e41b29cda1cef0d683c8bcfdc75 302 SUPERFAMILY SSF52540 9 194 2.29E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS12215 c3908e41b29cda1cef0d683c8bcfdc75 302 TIGRFAM TIGR03596 GTPase_YlqF: ribosome biogenesis GTP-binding protein YlqF 3 278 3.9E-110 T 28-03-2018 IPR019991 GTP-binding protein, ribosome biogenesis CIG75_RS12215 c3908e41b29cda1cef0d683c8bcfdc75 302 Pfam PF01926 50S ribosome-binding GTPase 123 212 3.1E-16 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CIG75_RS05890 83544b24073380180369e7d67efb2450 216 Pfam PF15607 Bacterial toxin 44 80 174 4.1E-18 T 28-03-2018 IPR028946 Bacterial toxin 44 CIG75_RS10530 9b738590ead57bd279b678908f186c13 162 Pfam PF02592 Putative vitamin uptake transporter 72 154 6.6E-11 T 28-03-2018 IPR003744 Queuosine precursor transporter CIG75_RS15615 296ae7be593dae0648895e7799b2aec1 182 Gene3D G3DSA:3.40.30.10 80 182 1.5E-18 T 28-03-2018 CIG75_RS15615 296ae7be593dae0648895e7799b2aec1 182 Pfam PF00085 Thioredoxin 91 181 1.2E-13 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 CIG75_RS15615 296ae7be593dae0648895e7799b2aec1 182 SUPERFAMILY SSF52833 86 181 2.81E-21 T 28-03-2018 IPR012336 Thioredoxin-like fold CIG75_RS04900 17cc31fc4e0d52f785ba3a24eb6c2ab6 201 Gene3D G3DSA:1.10.1050.10 144 201 1.7E-9 T 28-03-2018 CIG75_RS04900 17cc31fc4e0d52f785ba3a24eb6c2ab6 201 SUPERFAMILY SSF55174 5 201 1.77E-59 T 28-03-2018 CIG75_RS04900 17cc31fc4e0d52f785ba3a24eb6c2ab6 201 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 201 3.0E-74 T 28-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 CIG75_RS04900 17cc31fc4e0d52f785ba3a24eb6c2ab6 201 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 201 33.05 T 28-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 CIG75_RS04900 17cc31fc4e0d52f785ba3a24eb6c2ab6 201 Gene3D G3DSA:1.10.1050.10 1 93 1.4E-38 T 28-03-2018 CIG75_RS04900 17cc31fc4e0d52f785ba3a24eb6c2ab6 201 Gene3D G3DSA:3.10.290.10 94 143 9.4E-15 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CIG75_RS04900 17cc31fc4e0d52f785ba3a24eb6c2ab6 201 SMART SM01390 3 92 1.9E-41 T 28-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 CIG75_RS04900 17cc31fc4e0d52f785ba3a24eb6c2ab6 201 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 91 5.3E-29 T 28-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 CIG75_RS04900 17cc31fc4e0d52f785ba3a24eb6c2ab6 201 SMART SM00363 93 157 5.7E-13 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CIG75_RS04900 17cc31fc4e0d52f785ba3a24eb6c2ab6 201 Pfam PF01479 S4 domain 94 140 1.3E-15 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CIG75_RS15355 ba15c243eccbc5900b00d274256aed30 364 TIGRFAM TIGR02872 spore_ytvI: sporulation integral membrane protein YtvI 23 348 2.1E-84 T 28-03-2018 IPR014227 Sporulation integral membrane protein YtvI CIG75_RS15355 ba15c243eccbc5900b00d274256aed30 364 Pfam PF01594 AI-2E family transporter 15 345 3.9E-54 T 28-03-2018 IPR002549 Transmembrane protein TqsA-like CIG75_RS13050 916e72db019ac0c8316b7383ff25ee3a 184 SUPERFAMILY SSF53271 8 171 3.15E-45 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CIG75_RS13050 916e72db019ac0c8316b7383ff25ee3a 184 Gene3D G3DSA:3.40.50.2020 2 182 2.0E-38 T 28-03-2018 CIG75_RS13050 916e72db019ac0c8316b7383ff25ee3a 184 Hamap MF_01219 Bifunctional protein PyrR [pyrR]. 6 179 38.666 T 28-03-2018 IPR023050 Bifunctional protein PyrR KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 CIG75_RS13050 916e72db019ac0c8316b7383ff25ee3a 184 Pfam PF00156 Phosphoribosyl transferase domain 7 149 4.9E-24 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CIG75_RS02585 30ec174a088c167aaff26ad6f8b4bf94 356 SUPERFAMILY SSF56601 14 342 1.51E-73 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CIG75_RS02585 30ec174a088c167aaff26ad6f8b4bf94 356 Pfam PF00144 Beta-lactamase 17 337 4.4E-52 T 28-03-2018 IPR001466 Beta-lactamase-related CIG75_RS02585 30ec174a088c167aaff26ad6f8b4bf94 356 Gene3D G3DSA:3.40.710.10 6 351 4.9E-80 T 28-03-2018 CIG75_RS17680 0a4ace4a9f78bdad4688fe45b19739bd 158 Gene3D G3DSA:3.40.50.300 1 152 1.3E-49 T 28-03-2018 CIG75_RS17680 0a4ace4a9f78bdad4688fe45b19739bd 158 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 9 126 1.7E-37 T 28-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 CIG75_RS17680 0a4ace4a9f78bdad4688fe45b19739bd 158 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 13 138 9.6E-39 T 28-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 CIG75_RS17680 0a4ace4a9f78bdad4688fe45b19739bd 158 SUPERFAMILY SSF52540 20 122 7.02E-24 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS09600 1462afd657944553e134c7b1ed0aa70e 110 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 3 82 7.8E-14 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CIG75_RS09600 1462afd657944553e134c7b1ed0aa70e 110 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 3 84 6.2E-25 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CIG75_RS09600 1462afd657944553e134c7b1ed0aa70e 110 SUPERFAMILY SSF46767 2 85 2.22E-23 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CIG75_RS09600 1462afd657944553e134c7b1ed0aa70e 110 Gene3D G3DSA:1.10.10.10 1 109 2.5E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS18510 128b2934fe1f2ce286d142e275dead54 393 Pfam PF00534 Glycosyl transferases group 1 221 359 3.2E-29 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CIG75_RS18510 128b2934fe1f2ce286d142e275dead54 393 Gene3D G3DSA:3.40.50.2000 168 370 5.4E-35 T 28-03-2018 CIG75_RS18510 128b2934fe1f2ce286d142e275dead54 393 SUPERFAMILY SSF53756 60 383 1.61E-49 T 28-03-2018 CIG75_RS05475 d2f7edc02f7e64f2be05aa442a8d31b6 254 Gene3D G3DSA:3.40.50.720 45 253 8.4E-54 T 28-03-2018 CIG75_RS05475 d2f7edc02f7e64f2be05aa442a8d31b6 254 Gene3D G3DSA:3.40.50.720 1 44 7.4E-12 T 28-03-2018 CIG75_RS05475 d2f7edc02f7e64f2be05aa442a8d31b6 254 SUPERFAMILY SSF51735 2 250 3.16E-82 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS05475 d2f7edc02f7e64f2be05aa442a8d31b6 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 6.4E-33 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS05475 d2f7edc02f7e64f2be05aa442a8d31b6 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 6.4E-33 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS05475 d2f7edc02f7e64f2be05aa442a8d31b6 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 6.4E-33 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS05475 d2f7edc02f7e64f2be05aa442a8d31b6 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 6.4E-33 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS05475 d2f7edc02f7e64f2be05aa442a8d31b6 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 6.4E-33 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS05475 d2f7edc02f7e64f2be05aa442a8d31b6 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 6.4E-33 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS05475 d2f7edc02f7e64f2be05aa442a8d31b6 254 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 246 3.5E-59 T 28-03-2018 CIG75_RS05475 d2f7edc02f7e64f2be05aa442a8d31b6 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 1.2E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS05475 d2f7edc02f7e64f2be05aa442a8d31b6 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 1.2E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS05475 d2f7edc02f7e64f2be05aa442a8d31b6 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 1.2E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CIG75_RS08355 54b3160904f3e429376275e68cbaf508 163 Gene3D G3DSA:3.30.70.640 4 159 2.2E-69 T 28-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 CIG75_RS08355 54b3160904f3e429376275e68cbaf508 163 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase accessory protein [moaC]. 4 159 36.798 T 28-03-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 CIG75_RS08355 54b3160904f3e429376275e68cbaf508 163 Pfam PF01967 MoaC family 17 151 8.4E-56 T 28-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 CIG75_RS08355 54b3160904f3e429376275e68cbaf508 163 SUPERFAMILY SSF55040 13 156 9.55E-60 T 28-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 CIG75_RS08355 54b3160904f3e429376275e68cbaf508 163 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 6 153 4.2E-66 T 28-03-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 CIG75_RS07735 ed4226afbd688605d492ecda6bbdded7 453 Pfam PF00742 Homoserine dehydrogenase 143 320 6.4E-60 T 28-03-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CIG75_RS07735 ed4226afbd688605d492ecda6bbdded7 453 Gene3D G3DSA:3.40.50.720 6 163 4.6E-32 T 28-03-2018 CIG75_RS07735 ed4226afbd688605d492ecda6bbdded7 453 PIRSF PIRSF000098 7 431 7.9E-132 T 28-03-2018 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CIG75_RS07735 ed4226afbd688605d492ecda6bbdded7 453 SUPERFAMILY SSF55347 143 308 4.71E-49 T 28-03-2018 CIG75_RS07735 ed4226afbd688605d492ecda6bbdded7 453 Gene3D G3DSA:3.30.360.10 164 304 2.1E-48 T 28-03-2018 CIG75_RS07735 ed4226afbd688605d492ecda6bbdded7 453 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 189 211 - T 28-03-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CIG75_RS07735 ed4226afbd688605d492ecda6bbdded7 453 SUPERFAMILY SSF51735 7 164 3.16E-32 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS07735 ed4226afbd688605d492ecda6bbdded7 453 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 16 135 1.3E-17 T 28-03-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 CIG75_RS09020 d88b469d18c2011d054de6d4de12f657 64 TIGRFAM TIGR03412 iscX_yfhJ: FeS assembly protein IscX 3 61 5.2E-26 T 28-03-2018 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 CIG75_RS09020 d88b469d18c2011d054de6d4de12f657 64 Pfam PF04384 Iron-sulphur cluster assembly 1 61 5.5E-26 T 28-03-2018 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 CIG75_RS09020 d88b469d18c2011d054de6d4de12f657 64 Gene3D G3DSA:1.10.10.600 1 61 2.4E-26 T 28-03-2018 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 CIG75_RS09020 d88b469d18c2011d054de6d4de12f657 64 PIRSF PIRSF039003 1 64 5.0E-26 T 28-03-2018 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 CIG75_RS09020 d88b469d18c2011d054de6d4de12f657 64 SUPERFAMILY SSF140319 1 61 2.35E-21 T 28-03-2018 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 CIG75_RS18115 5f974784a51ccea4185351221ce40dfc 275 Pfam PF05138 Phenylacetic acid catabolic protein 22 259 8.7E-39 T 28-03-2018 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 CIG75_RS18115 5f974784a51ccea4185351221ce40dfc 275 SUPERFAMILY SSF47240 32 265 4.49E-49 T 28-03-2018 IPR009078 Ferritin-like superfamily CIG75_RS18115 5f974784a51ccea4185351221ce40dfc 275 Gene3D G3DSA:1.20.1260.10 22 272 1.2E-54 T 28-03-2018 IPR012347 Ferritin-related CIG75_RS19710 620aa35577504a6a429ffbd5f89fbcca 111 Gene3D G3DSA:3.90.470.10 1 111 1.2E-45 T 28-03-2018 CIG75_RS19710 620aa35577504a6a429ffbd5f89fbcca 111 SUPERFAMILY SSF54843 3 111 1.27E-44 T 28-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 CIG75_RS19710 620aa35577504a6a429ffbd5f89fbcca 111 ProSitePatterns PS00464 Ribosomal protein L22 signature. 84 108 - T 28-03-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CIG75_RS19710 620aa35577504a6a429ffbd5f89fbcca 111 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 2 111 31.223 T 28-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS19710 620aa35577504a6a429ffbd5f89fbcca 111 Pfam PF00237 Ribosomal protein L22p/L17e 6 108 2.8E-38 T 28-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 CIG75_RS19710 620aa35577504a6a429ffbd5f89fbcca 111 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 6 107 2.4E-50 T 28-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS09145 8602e8363d22647c1caaad45bde6371b 230 PIRSF PIRSF033094 1 230 5.5E-97 T 28-03-2018 IPR014578 Predicted phosphoesterase, CT488 type CIG75_RS09145 8602e8363d22647c1caaad45bde6371b 230 Pfam PF00149 Calcineurin-like phosphoesterase 1 196 1.2E-16 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CIG75_RS09145 8602e8363d22647c1caaad45bde6371b 230 Gene3D G3DSA:3.60.21.10 1 215 1.2E-23 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CIG75_RS09145 8602e8363d22647c1caaad45bde6371b 230 SUPERFAMILY SSF56300 1 203 8.5E-28 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CIG75_RS05755 ac3016e14c86110e7993ab46fa1ba7e3 238 Gene3D G3DSA:1.20.58.220 133 237 5.9E-5 T 28-03-2018 CIG75_RS05755 ac3016e14c86110e7993ab46fa1ba7e3 238 Pfam PF01865 Protein of unknown function DUF47 39 235 2.0E-31 T 28-03-2018 IPR018445 Putative phosphate transport regulator CIG75_RS05355 575135fc035f2ebf85d9cefeff904246 257 Gene3D G3DSA:1.10.3210.10 34 241 1.0E-49 T 28-03-2018 CIG75_RS05355 575135fc035f2ebf85d9cefeff904246 257 SUPERFAMILY SSF109604 57 227 3.14E-39 T 28-03-2018 CIG75_RS05355 575135fc035f2ebf85d9cefeff904246 257 SMART SM00471 64 199 2.7E-11 T 28-03-2018 IPR003607 HD/PDEase domain CIG75_RS05355 575135fc035f2ebf85d9cefeff904246 257 Pfam PF01966 HD domain 71 189 9.2E-20 T 28-03-2018 IPR006674 HD domain CIG75_RS02010 b3f4b7dc7379254b8fde1d3bb1835fb0 82 Pfam PF06612 Protein of unknown function (DUF1146) 25 67 7.1E-13 T 28-03-2018 IPR009526 Protein of unknown function DUF1146 CIG75_RS02830 474661b641a5d3f0f336796209333260 208 PIRSF PIRSF006324 1 208 4.5E-54 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CIG75_RS02830 474661b641a5d3f0f336796209333260 208 Pfam PF01810 LysE type translocator 17 206 5.3E-32 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CIG75_RS08175 110785dd96a8c32d44581a62be17958f 124 Pfam PF07963 Prokaryotic N-terminal methylation motif 9 34 2.0E-8 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site CIG75_RS08175 110785dd96a8c32d44581a62be17958f 124 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 12 32 - T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site CIG75_RS08175 110785dd96a8c32d44581a62be17958f 124 SUPERFAMILY SSF54523 14 117 4.6E-18 T 28-03-2018 CIG75_RS08175 110785dd96a8c32d44581a62be17958f 124 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 11 34 1.9E-7 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site CIG75_RS08175 110785dd96a8c32d44581a62be17958f 124 Gene3D G3DSA:3.30.700.10 14 119 8.1E-18 T 28-03-2018 CIG75_RS00315 c14dc83f48d08704464dea25db1a1427 222 SUPERFAMILY SSF53163 16 199 1.44E-51 T 28-03-2018 IPR023430 Peptidase HybD-like domain CIG75_RS00315 c14dc83f48d08704464dea25db1a1427 222 Gene3D G3DSA:3.40.50.1450 9 174 8.3E-35 T 28-03-2018 IPR023430 Peptidase HybD-like domain CIG75_RS00315 c14dc83f48d08704464dea25db1a1427 222 Pfam PF06866 Protein of unknown function (DUF1256) 18 180 4.7E-61 T 28-03-2018 IPR009665 Protein of unknown function DUF1256 CIG75_RS00315 c14dc83f48d08704464dea25db1a1427 222 TIGRFAM TIGR02841 spore_YyaC: putative sporulation protein YyaC 42 181 5.2E-65 T 28-03-2018 IPR009665 Protein of unknown function DUF1256 CIG75_RS05795 012550bd05bd96e060b98fa08644f698 394 SUPERFAMILY SSF53383 4 384 4.36E-106 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CIG75_RS05795 012550bd05bd96e060b98fa08644f698 394 Gene3D G3DSA:3.90.1150.10 255 385 1.9E-41 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CIG75_RS05795 012550bd05bd96e060b98fa08644f698 394 Pfam PF00155 Aminotransferase class I and II 31 382 1.2E-62 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CIG75_RS05795 012550bd05bd96e060b98fa08644f698 394 Gene3D G3DSA:3.90.1150.10 7 254 1.7E-36 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CIG75_RS05795 012550bd05bd96e060b98fa08644f698 394 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 236 249 - T 28-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CIG75_RS08145 7cf758184577e63b768ed143e2d791d9 263 Pfam PF01925 Sulfite exporter TauE/SafE 7 260 3.0E-55 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 CIG75_RS08145 7cf758184577e63b768ed143e2d791d9 263 Gene3D G3DSA:1.20.1250.20 4 136 2.8E-4 T 28-03-2018 CIG75_RS08035 7d2d968288475d79c28d698952895106 189 Pfam PF01478 Type IV leader peptidase family 45 146 3.7E-16 T 28-03-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 CIG75_RS00025 504af8439e31374b2dffab79bd4fe959 148 SUPERFAMILY SSF158397 30 147 1.7E-31 T 28-03-2018 CIG75_RS00025 504af8439e31374b2dffab79bd4fe959 148 Gene3D G3DSA:1.20.120.490 30 147 1.5E-34 T 28-03-2018 IPR024042 Hypothetical protein TM1646-like domain CIG75_RS00025 504af8439e31374b2dffab79bd4fe959 148 Pfam PF03885 Protein of unknown function (DUF327) 21 147 2.3E-37 T 28-03-2018 IPR005585 Protein of unknown function DUF327 CIG75_RS07970 80cef85769a95cb17550dbabf2095850 695 Gene3D G3DSA:3.10.350.10 642 695 2.7E-8 T 28-03-2018 CIG75_RS07970 80cef85769a95cb17550dbabf2095850 695 SMART SM00257 648 691 1.6E-7 T 28-03-2018 IPR018392 LysM domain CIG75_RS07970 80cef85769a95cb17550dbabf2095850 695 SUPERFAMILY SSF54106 650 691 1.44E-7 T 28-03-2018 IPR018392 LysM domain CIG75_RS07970 80cef85769a95cb17550dbabf2095850 695 Pfam PF01476 LysM domain 651 691 6.0E-10 T 28-03-2018 IPR018392 LysM domain CIG75_RS10660 04af3d2eee7d80e68bf3a6434a23373f 358 Pfam PF03060 Nitronate monooxygenase 5 344 4.6E-102 T 28-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 CIG75_RS10660 04af3d2eee7d80e68bf3a6434a23373f 358 SUPERFAMILY SSF51412 2 353 5.8E-71 T 28-03-2018 CIG75_RS10660 04af3d2eee7d80e68bf3a6434a23373f 358 Gene3D G3DSA:3.20.20.70 1 358 1.4E-66 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CIG75_RS12390 cc2bf0168c483bd5f63b855552ccc356 185 Pfam PF02620 Uncharacterized ACR, COG1399 65 180 4.2E-28 T 28-03-2018 IPR003772 Large ribosomal RNA subunit accumulation protein YceD CIG75_RS15715 c6ba9e332b10447b2e5ac8a033c15682 234 Gene3D G3DSA:3.40.50.880 1 223 1.1E-45 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CIG75_RS15715 c6ba9e332b10447b2e5ac8a033c15682 234 Pfam PF03575 Peptidase family S51 4 199 7.4E-54 T 28-03-2018 IPR005320 Peptidase S51 GO:0006508|GO:0008236 CIG75_RS15715 c6ba9e332b10447b2e5ac8a033c15682 234 SUPERFAMILY SSF52317 4 198 1.5E-28 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CIG75_RS09345 a3e53c7b3228e3aab0efe9964570b5e6 226 Pfam PF02224 Cytidylate kinase 6 218 3.3E-77 T 28-03-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 CIG75_RS09345 a3e53c7b3228e3aab0efe9964570b5e6 226 TIGRFAM TIGR00017 cmk: cytidylate kinase 4 216 4.7E-79 T 28-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 CIG75_RS09345 a3e53c7b3228e3aab0efe9964570b5e6 226 Gene3D G3DSA:3.40.50.300 1 222 4.2E-56 T 28-03-2018 CIG75_RS09345 a3e53c7b3228e3aab0efe9964570b5e6 226 SUPERFAMILY SSF52540 1 219 2.54E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS09345 a3e53c7b3228e3aab0efe9964570b5e6 226 Hamap MF_00238 Cytidylate kinase [cmk]. 4 222 33.087 T 28-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 CIG75_RS02440 5c4f0671784f5f45535f72d62c804d14 355 Gene3D G3DSA:3.20.20.70 1 288 1.2E-92 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CIG75_RS02440 5c4f0671784f5f45535f72d62c804d14 355 TIGRFAM TIGR03569 NeuB_NnaB: N-acetylneuraminate synthase 4 355 1.3E-151 T 28-03-2018 IPR020007 N-acetylneuraminate synthase KEGG: 00520+2.5.1.101|KEGG: 00900+2.5.1.10|MetaCyc: PWY-5123|MetaCyc: PWY-6749|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7131|MetaCyc: PWY-7721|MetaCyc: PWY-7736 CIG75_RS02440 5c4f0671784f5f45535f72d62c804d14 355 SUPERFAMILY SSF51569 3 312 1.26E-85 T 28-03-2018 CIG75_RS02440 5c4f0671784f5f45535f72d62c804d14 355 Gene3D G3DSA:3.90.1210.10 293 355 1.1E-19 T 28-03-2018 CIG75_RS02440 5c4f0671784f5f45535f72d62c804d14 355 SUPERFAMILY SSF51269 295 355 3.14E-17 T 28-03-2018 IPR006190 Antifreeze-like/N-acetylneuraminic acid synthase C-terminal Reactome: R-HSA-4085001 CIG75_RS02440 5c4f0671784f5f45535f72d62c804d14 355 Pfam PF03102 NeuB family 24 286 2.0E-101 T 28-03-2018 IPR013132 N-acetylneuraminic acid synthase, N-terminal GO:0016051 Reactome: R-HSA-4085001 CIG75_RS02440 5c4f0671784f5f45535f72d62c804d14 355 Pfam PF08666 SAF domain 304 331 5.6E-5 T 28-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 CIG75_RS08715 bb47fa62706890f42bfb4c9d2b6cdc49 339 TIGRFAM TIGR02845 spore_V_AD: stage V sporulation protein AD 6 334 1.4E-157 T 28-03-2018 IPR010894 Stage V sporulation AD CIG75_RS08715 bb47fa62706890f42bfb4c9d2b6cdc49 339 Pfam PF07451 Stage V sporulation protein AD (SpoVAD) 5 334 2.3E-158 T 28-03-2018 IPR010894 Stage V sporulation AD CIG75_RS08715 bb47fa62706890f42bfb4c9d2b6cdc49 339 PIRSF PIRSF011570 1 337 4.7E-159 T 28-03-2018 IPR010894 Stage V sporulation AD CIG75_RS08715 bb47fa62706890f42bfb4c9d2b6cdc49 339 SUPERFAMILY SSF53901 56 311 2.88E-18 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS08715 bb47fa62706890f42bfb4c9d2b6cdc49 339 Gene3D G3DSA:3.40.47.10 17 174 2.5E-11 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS16825 8403ddd712766eae568879959fe64aaa 390 Pfam PF12051 Protein of unknown function (DUF3533) 14 351 1.8E-18 T 28-03-2018 IPR022703 Domain of unknown function DUF3533 CIG75_RS16825 8403ddd712766eae568879959fe64aaa 390 Gene3D G3DSA:3.40.1710.10 28 217 2.9E-26 T 28-03-2018 CIG75_RS19785 090af3507a103a1f1792ebb59d934360 163 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 2 160 28.349 T 28-03-2018 IPR022973 Ribosomal protein L10 CIG75_RS19785 090af3507a103a1f1792ebb59d934360 163 Gene3D G3DSA:3.40.50.720 4 105 0.0011 T 28-03-2018 CIG75_RS19785 090af3507a103a1f1792ebb59d934360 163 Pfam PF00466 Ribosomal protein L10 4 100 1.0E-29 T 28-03-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 CIG75_RS19785 090af3507a103a1f1792ebb59d934360 163 SUPERFAMILY SSF160369 3 159 2.22E-54 T 28-03-2018 CIG75_RS19785 090af3507a103a1f1792ebb59d934360 163 ProSitePatterns PS01109 Ribosomal protein L10 signature. 7 41 - T 28-03-2018 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS01845 4a0cc69e2d4e3c7fdd2b6336e9983f29 188 Pfam PF02659 Putative manganese efflux pump 36 187 1.1E-42 T 28-03-2018 IPR003810 Putative manganese efflux pump CIG75_RS01845 4a0cc69e2d4e3c7fdd2b6336e9983f29 188 Hamap MF_01521 Probable manganese efflux pump MntP [mntP]. 7 188 20.486 T 28-03-2018 IPR022929 Putative manganese efflux pump MntP CIG75_RS12690 e8c53d8324fffbcf23ee61d85ca0e265 295 SUPERFAMILY SSF53187 3 191 2.67E-40 T 28-03-2018 CIG75_RS12690 e8c53d8324fffbcf23ee61d85ca0e265 295 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 5 187 3.4E-37 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CIG75_RS12690 e8c53d8324fffbcf23ee61d85ca0e265 295 SMART SM00646 76 188 2.7E-25 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CIG75_RS12690 e8c53d8324fffbcf23ee61d85ca0e265 295 Gene3D G3DSA:3.40.630.40 1 196 5.8E-46 T 28-03-2018 CIG75_RS01865 64124bce1c9591c1027a0c0144141bc7 250 Pfam PF14491 Protein of unknown function (DUF4435) 7 218 3.6E-14 T 28-03-2018 IPR029492 Domain of unknown function DUF4435 CIG75_RS11955 bd866245f0c4aa43fc57a4d09abd3056 291 Pfam PF13614 AAA domain 25 184 2.5E-16 T 28-03-2018 IPR025669 AAA domain CIG75_RS11955 bd866245f0c4aa43fc57a4d09abd3056 291 PIRSF PIRSF003092 1 291 7.9E-84 T 28-03-2018 IPR025501 ATP binding protein MinD CIG75_RS11955 bd866245f0c4aa43fc57a4d09abd3056 291 Gene3D G3DSA:3.40.50.300 24 268 4.3E-47 T 28-03-2018 CIG75_RS11955 bd866245f0c4aa43fc57a4d09abd3056 291 SUPERFAMILY SSF52540 25 270 3.92E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS03980 a94b670ba86628642c133fd8cb73d591 140 Pfam PF14275 Domain of unknown function (DUF4362) 33 121 2.4E-22 T 28-03-2018 IPR025372 Protein of unknown function DUF4362 CIG75_RS15180 577cbc9922fceb81d00218977f0d5520 105 Gene3D G3DSA:1.20.1260.10 1 76 4.9E-5 T 28-03-2018 IPR012347 Ferritin-related CIG75_RS15180 577cbc9922fceb81d00218977f0d5520 105 Pfam PF07875 Coat F domain 18 80 2.6E-18 T 28-03-2018 IPR012851 Spore coat protein CotF-like CIG75_RS02015 4d8e42a395b3b3eab2e26da27da72eb8 252 Gene3D G3DSA:3.30.2030.10 39 174 1.5E-4 T 28-03-2018 CIG75_RS02015 4d8e42a395b3b3eab2e26da27da72eb8 252 Pfam PF08680 TATA-box binding 53 252 2.5E-44 T 28-03-2018 IPR014794 TATA-box binding CIG75_RS02015 4d8e42a395b3b3eab2e26da27da72eb8 252 SUPERFAMILY SSF143842 37 250 3.79E-29 T 28-03-2018 IPR014794 TATA-box binding CIG75_RS02015 4d8e42a395b3b3eab2e26da27da72eb8 252 Gene3D G3DSA:3.30.360.40 182 252 3.6E-23 T 28-03-2018 CIG75_RS15905 dd2c7d670360e9af3803ec9861c24a71 253 Gene3D G3DSA:3.40.50.720 2 253 3.5E-45 T 28-03-2018 CIG75_RS15905 dd2c7d670360e9af3803ec9861c24a71 253 SUPERFAMILY SSF69572 3 250 2.09E-59 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CIG75_RS15905 dd2c7d670360e9af3803ec9861c24a71 253 Pfam PF00899 ThiF family 7 164 7.0E-38 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CIG75_RS06900 8b226119e0c9011b8db28a80668a966d 135 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 28-03-2018 IPR030489 Transcription regulator Rrf2-type, conserved site CIG75_RS06900 8b226119e0c9011b8db28a80668a966d 135 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 121 4.0E-35 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type CIG75_RS06900 8b226119e0c9011b8db28a80668a966d 135 SUPERFAMILY SSF46785 2 123 1.31E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS06900 8b226119e0c9011b8db28a80668a966d 135 Pfam PF02082 Transcriptional regulator 1 82 2.1E-28 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type CIG75_RS06900 8b226119e0c9011b8db28a80668a966d 135 Gene3D G3DSA:1.10.10.10 1 135 4.0E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS01775 be7f5c165f542b27766d0daa44053fb7 423 Gene3D G3DSA:3.20.20.70 179 403 2.2E-20 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CIG75_RS01775 be7f5c165f542b27766d0daa44053fb7 423 SUPERFAMILY SSF102114 180 372 3.27E-17 T 28-03-2018 CIG75_RS01775 be7f5c165f542b27766d0daa44053fb7 423 Pfam PF04055 Radical SAM superfamily 181 354 1.7E-9 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CIG75_RS20100 71d70dc4808f225e7828acdade476c56 119 TIGRFAM TIGR00526 folB_dom: FolB domain 1 119 4.6E-33 T 28-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CIG75_RS20100 71d70dc4808f225e7828acdade476c56 119 Gene3D G3DSA:3.30.1130.10 1 119 3.0E-34 T 28-03-2018 CIG75_RS20100 71d70dc4808f225e7828acdade476c56 119 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 3 116 9.9E-39 T 28-03-2018 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CIG75_RS20100 71d70dc4808f225e7828acdade476c56 119 SUPERFAMILY SSF55620 2 119 2.0E-37 T 28-03-2018 CIG75_RS20100 71d70dc4808f225e7828acdade476c56 119 Pfam PF02152 Dihydroneopterin aldolase 4 115 2.0E-34 T 28-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CIG75_RS20100 71d70dc4808f225e7828acdade476c56 119 SMART SM00905 4 117 3.9E-46 T 28-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CIG75_RS17750 c5cac9e9b133bdca688ce5c02e51a978 124 Gene3D G3DSA:2.60.40.10 1 95 1.6E-5 T 28-03-2018 IPR013783 Immunoglobulin-like fold CIG75_RS17750 c5cac9e9b133bdca688ce5c02e51a978 124 Pfam PF12690 Intracellular proteinase inhibitor 18 85 6.1E-19 T 28-03-2018 IPR020481 Intracellular proteinase inhibitor BsuPI CIG75_RS17750 c5cac9e9b133bdca688ce5c02e51a978 124 ProDom PD076312 INHIBITOR INTRACELLULAR PROTEINASE PRECURSOR SIGNAL DOMAIN SLH S-LAYER PROTEASE BSUPI 15 98 4.0E-5 T 28-03-2018 IPR020481 Intracellular proteinase inhibitor BsuPI CIG75_RS13790 b305f7d7aa1187bfbf4e911f7a8f7421 234 Gene3D G3DSA:1.25.40.10 1 79 2.8E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS13790 b305f7d7aa1187bfbf4e911f7a8f7421 234 Gene3D G3DSA:1.25.40.10 80 221 1.7E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS13790 b305f7d7aa1187bfbf4e911f7a8f7421 234 SUPERFAMILY SSF48452 2 63 2.56E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS13790 b305f7d7aa1187bfbf4e911f7a8f7421 234 SMART SM00028 35 68 35.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS13790 b305f7d7aa1187bfbf4e911f7a8f7421 234 SMART SM00028 153 186 89.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS13790 b305f7d7aa1187bfbf4e911f7a8f7421 234 SMART SM00028 1 30 270.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS13790 b305f7d7aa1187bfbf4e911f7a8f7421 234 SMART SM00028 115 148 45.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS13790 b305f7d7aa1187bfbf4e911f7a8f7421 234 Pfam PF13181 Tetratricopeptide repeat 2 27 0.013 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS13790 b305f7d7aa1187bfbf4e911f7a8f7421 234 SUPERFAMILY SSF48452 76 217 1.06E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS15965 9706205d64794dd8cacc431fb51c6394 139 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 5 133 9.0E-13 T 28-03-2018 IPR028973 PhnB-like CIG75_RS15965 9706205d64794dd8cacc431fb51c6394 139 SUPERFAMILY SSF54593 5 134 9.58E-39 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CIG75_RS15965 9706205d64794dd8cacc431fb51c6394 139 Gene3D G3DSA:3.10.180.10 1 139 4.0E-31 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CIG75_RS04015 9e3e589c033338992b67205bca7f7e26 320 Gene3D G3DSA:1.10.1670.10 270 320 1.2E-12 T 28-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CIG75_RS04015 9e3e589c033338992b67205bca7f7e26 320 Gene3D G3DSA:1.10.340.30 147 267 1.3E-27 T 28-03-2018 CIG75_RS04015 9e3e589c033338992b67205bca7f7e26 320 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 154 303 7.1E-15 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CIG75_RS04015 9e3e589c033338992b67205bca7f7e26 320 ProSitePatterns PS00516 Alkylbase DNA glycosidases alkA family signature. 251 275 - T 28-03-2018 IPR000035 Alkylbase DNA glycosidase, conserved site GO:0003905|GO:0006281 CIG75_RS04015 9e3e589c033338992b67205bca7f7e26 320 SMART SM00478 156 320 8.6E-28 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CIG75_RS04015 9e3e589c033338992b67205bca7f7e26 320 Gene3D G3DSA:3.30.310.20 26 146 2.6E-17 T 28-03-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal CIG75_RS04015 9e3e589c033338992b67205bca7f7e26 320 SUPERFAMILY SSF48150 135 319 6.8E-46 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CIG75_RS14360 432bcea9ac161ac5011280845fb0b348 162 Pfam PF12870 Domain of unknown function (DUF4878) 59 157 1.2E-6 T 28-03-2018 IPR024267 Domain of unknown function (DUF4878) CIG75_RS02695 74d8f8d51026a8708d0abbe335bed6fd 499 Gene3D G3DSA:3.30.559.10 44 258 4.2E-41 T 28-03-2018 CIG75_RS02695 74d8f8d51026a8708d0abbe335bed6fd 499 SUPERFAMILY SSF52777 242 492 9.67E-53 T 28-03-2018 CIG75_RS02695 74d8f8d51026a8708d0abbe335bed6fd 499 Pfam PF00668 Condensation domain 54 497 8.2E-111 T 28-03-2018 IPR001242 Condensation domain CIG75_RS02695 74d8f8d51026a8708d0abbe335bed6fd 499 Gene3D G3DSA:1.10.1200.10 1 43 4.1E-4 T 28-03-2018 CIG75_RS02695 74d8f8d51026a8708d0abbe335bed6fd 499 SUPERFAMILY SSF52777 60 235 8.89E-48 T 28-03-2018 CIG75_RS02695 74d8f8d51026a8708d0abbe335bed6fd 499 SUPERFAMILY SSF47336 2 69 4.73E-6 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CIG75_RS01380 6ea9fd006bd75b4afb6d6aecdcc0bc77 128 Pfam PF04241 Protein of unknown function (DUF423) 19 106 6.2E-29 T 28-03-2018 IPR006696 Protein of unknown function DUF423 CIG75_RS05175 c7a9f8340bf9cf95e4de82710f40bb3e 196 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 37 181 7.9E-16 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS05175 c7a9f8340bf9cf95e4de82710f40bb3e 196 Gene3D G3DSA:1.10.10.10 104 194 5.7E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS05175 c7a9f8340bf9cf95e4de82710f40bb3e 196 SUPERFAMILY SSF88659 112 182 1.07E-13 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS05175 c7a9f8340bf9cf95e4de82710f40bb3e 196 Pfam PF08281 Sigma-70, region 4 127 175 2.4E-10 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS17485 542c48f25c9963557ba69ed3864fff0a 139 Gene3D G3DSA:3.40.50.300 7 131 6.4E-18 T 28-03-2018 CIG75_RS17485 542c48f25c9963557ba69ed3864fff0a 139 Pfam PF00270 DEAD/DEAH box helicase 22 107 6.0E-12 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CIG75_RS17485 542c48f25c9963557ba69ed3864fff0a 139 SUPERFAMILY SSF52540 9 127 1.98E-19 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS02580 4c07b0c4db26e789f44de9a068b9b456 906 SUPERFAMILY SSF51556 775 850 1.42E-16 T 28-03-2018 IPR032466 Metal-dependent hydrolase CIG75_RS02580 4c07b0c4db26e789f44de9a068b9b456 906 SUPERFAMILY SSF51556 534 635 1.42E-16 T 28-03-2018 IPR032466 Metal-dependent hydrolase CIG75_RS02580 4c07b0c4db26e789f44de9a068b9b456 906 ProSitePatterns PS00485 Adenosine and AMP deaminase signature. 826 832 - T 28-03-2018 IPR006650 Adenosine/AMP deaminase active site GO:0009168|GO:0019239 Reactome: R-HSA-74217 CIG75_RS02580 4c07b0c4db26e789f44de9a068b9b456 906 Pfam PF00962 Adenosine/AMP deaminase 731 846 4.7E-5 T 28-03-2018 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 CIG75_RS02580 4c07b0c4db26e789f44de9a068b9b456 906 Gene3D G3DSA:3.20.20.140 177 884 3.5E-43 T 28-03-2018 CIG75_RS08755 2d82653a772104d61c69a5023df0bcf5 456 Pfam PF02386 Cation transport protein 45 438 1.2E-51 T 28-03-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 CIG75_RS08755 2d82653a772104d61c69a5023df0bcf5 456 TIGRFAM TIGR00933 2a38: potassium uptake protein, TrkH family 36 425 6.5E-101 T 28-03-2018 IPR004772 TrkH potassium transport family GO:0016021|GO:0022820|GO:0071805 CIG75_RS08755 2d82653a772104d61c69a5023df0bcf5 456 Gene3D G3DSA:1.10.287.70 17 236 0.2 T 28-03-2018 CIG75_RS07050 276b8da9bb88c79ed9211ae8d77fa40a 279 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 11 93 1.5E-31 T 28-03-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 CIG75_RS07050 276b8da9bb88c79ed9211ae8d77fa40a 279 SUPERFAMILY SSF53223 2 105 3.17E-37 T 28-03-2018 CIG75_RS07050 276b8da9bb88c79ed9211ae8d77fa40a 279 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 121 196 1.2E-9 T 28-03-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase CIG75_RS07050 276b8da9bb88c79ed9211ae8d77fa40a 279 Gene3D G3DSA:3.40.50.10860 1 115 2.3E-47 T 28-03-2018 CIG75_RS07050 276b8da9bb88c79ed9211ae8d77fa40a 279 SUPERFAMILY SSF51735 106 277 1.9E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS07050 276b8da9bb88c79ed9211ae8d77fa40a 279 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 6 277 37.392 T 28-03-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 CIG75_RS07050 276b8da9bb88c79ed9211ae8d77fa40a 279 Gene3D G3DSA:3.40.50.720 116 278 3.7E-41 T 28-03-2018 CIG75_RS07050 276b8da9bb88c79ed9211ae8d77fa40a 279 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 8 277 5.9E-89 T 28-03-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 CIG75_RS18980 3400fe09fa1cde49e71ef564ae271c1c 133 Pfam PF04883 Bacteriophage HK97-gp10, putative tail-component 14 89 1.1E-16 T 28-03-2018 IPR010064 Bacteriophage HK97-gp10, putative tail-component CIG75_RS05485 4139feffa6838856b950c5d11e762a72 477 Pfam PF04286 Protein of unknown function (DUF445) 39 476 4.6E-51 T 28-03-2018 IPR007383 Protein of unknown function DUF445 CIG75_RS00325 d8606209b97c1e18226d94453b54f571 86 Pfam PF11823 Protein of unknown function (DUF3343) 5 72 6.1E-18 T 28-03-2018 IPR021778 Domain of unknown function DUF3343 CIG75_RS17705 e9b277e98713cab108ef42cb093a937d 200 PIRSF PIRSF000709 1 101 1.1E-6 T 28-03-2018 CIG75_RS17705 e9b277e98713cab108ef42cb093a937d 200 SUPERFAMILY SSF53254 1 197 1.47E-44 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CIG75_RS17705 e9b277e98713cab108ef42cb093a937d 200 SMART SM00855 2 153 9.6E-18 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CIG75_RS17705 e9b277e98713cab108ef42cb093a937d 200 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 193 4.0E-41 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CIG75_RS17705 e9b277e98713cab108ef42cb093a937d 200 Gene3D G3DSA:3.40.50.1240 1 200 1.5E-43 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CIG75_RS09120 fb2daf76933a31f7d72d35ade4bea689 202 ProDom PD102989 YKOP PLASMID 6 143 3.0E-17 T 28-03-2018 CIG75_RS03730 fd00ce0c1e75b42d60105f17c6777794 266 Pfam PF00520 Ion transport protein 6 196 7.1E-20 T 28-03-2018 IPR005821 Ion transport domain GO:0005216|GO:0006811|GO:0016020|GO:0055085 CIG75_RS03730 fd00ce0c1e75b42d60105f17c6777794 266 Gene3D G3DSA:1.20.5.110 164 200 4.6E-13 T 28-03-2018 CIG75_RS03730 fd00ce0c1e75b42d60105f17c6777794 266 SUPERFAMILY SSF81324 5 198 1.07E-40 T 28-03-2018 CIG75_RS03730 fd00ce0c1e75b42d60105f17c6777794 266 Gene3D G3DSA:1.20.120.350 1 111 2.2E-9 T 28-03-2018 CIG75_RS03730 fd00ce0c1e75b42d60105f17c6777794 266 Gene3D G3DSA:1.10.287.70 112 162 2.6E-14 T 28-03-2018 CIG75_RS07920 1802c9734ad3efcd1dc740d3af6cff76 431 Pfam PF00860 Permease family 11 390 1.3E-62 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CIG75_RS03865 31d354877267f870e4633cb636b3dfb5 648 Gene3D G3DSA:1.10.287.510 277 387 5.5E-7 T 28-03-2018 CIG75_RS03865 31d354877267f870e4633cb636b3dfb5 648 Gene3D G3DSA:1.10.287.510 388 471 0.004 T 28-03-2018 CIG75_RS03865 31d354877267f870e4633cb636b3dfb5 648 SUPERFAMILY SSF52540 20 137 4.56E-5 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS03865 31d354877267f870e4633cb636b3dfb5 648 SUPERFAMILY SSF52540 198 287 4.56E-5 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS03865 31d354877267f870e4633cb636b3dfb5 648 Pfam PF12532 Protein of unknown function (DUF3732) 458 648 7.4E-55 T 28-03-2018 IPR022205 Protein of unknown function DUF3732 CIG75_RS16720 5cffab6b6e812a640c361d3eef801d78 81 SUPERFAMILY SSF46609 13 63 2.62E-6 T 28-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CIG75_RS18785 a998ae8021e5c9e29a5e62dd879cb675 201 Gene3D G3DSA:3.90.550.10 1 199 6.4E-37 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CIG75_RS18785 a998ae8021e5c9e29a5e62dd879cb675 201 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 1 192 20.622 T 28-03-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 CIG75_RS18785 a998ae8021e5c9e29a5e62dd879cb675 201 SUPERFAMILY SSF53448 1 190 1.17E-33 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CIG75_RS18785 a998ae8021e5c9e29a5e62dd879cb675 201 Pfam PF12804 MobA-like NTP transferase domain 3 162 1.2E-36 T 28-03-2018 IPR025877 MobA-like NTP transferase CIG75_RS00760 428cc7a961973ef9261a281bc2cf7616 195 Gene3D G3DSA:3.40.50.360 1 194 7.2E-36 T 28-03-2018 IPR029039 Flavoprotein-like domain CIG75_RS00760 428cc7a961973ef9261a281bc2cf7616 195 SUPERFAMILY SSF52218 2 193 2.1E-44 T 28-03-2018 IPR029039 Flavoprotein-like domain CIG75_RS00760 428cc7a961973ef9261a281bc2cf7616 195 Pfam PF02525 Flavodoxin-like fold 2 176 1.4E-36 T 28-03-2018 IPR003680 Flavodoxin-like fold CIG75_RS05105 27c2809efa31183529bfc2de98f05425 224 Gene3D G3DSA:2.40.260.10 43 223 6.3E-34 T 28-03-2018 IPR023365 Sortase domain CIG75_RS05105 27c2809efa31183529bfc2de98f05425 224 TIGRFAM TIGR01076 sortase_fam: sortase 98 222 2.4E-26 T 28-03-2018 IPR005754 Sortase family CIG75_RS05105 27c2809efa31183529bfc2de98f05425 224 Pfam PF04203 Sortase family 100 222 5.5E-28 T 28-03-2018 IPR005754 Sortase family CIG75_RS05105 27c2809efa31183529bfc2de98f05425 224 SUPERFAMILY SSF63817 91 223 2.09E-32 T 28-03-2018 IPR023365 Sortase domain CIG75_RS17955 5020a1e65879d402c2fc897da36ee0a9 127 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 8 124 2.0E-8 T 28-03-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CIG75_RS17955 5020a1e65879d402c2fc897da36ee0a9 127 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 5 119 1.6E-19 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CIG75_RS17955 5020a1e65879d402c2fc897da36ee0a9 127 Gene3D G3DSA:3.90.470.20 1 127 4.7E-37 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CIG75_RS17955 5020a1e65879d402c2fc897da36ee0a9 127 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 3 124 23.29 T 28-03-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CIG75_RS17955 5020a1e65879d402c2fc897da36ee0a9 127 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 1 124 3.1E-33 T 28-03-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CIG75_RS17955 5020a1e65879d402c2fc897da36ee0a9 127 SUPERFAMILY SSF56214 1 124 2.88E-31 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CIG75_RS17955 5020a1e65879d402c2fc897da36ee0a9 127 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 2 124 2.9E-29 T 28-03-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CIG75_RS16850 d1135f9e006fb7b7a56cee5b5f6e3e11 336 Pfam PF01032 FecCD transport family 22 331 1.5E-87 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CIG75_RS16850 d1135f9e006fb7b7a56cee5b5f6e3e11 336 SUPERFAMILY SSF81345 11 331 7.59E-78 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CIG75_RS16850 d1135f9e006fb7b7a56cee5b5f6e3e11 336 Gene3D G3DSA:1.10.3470.10 8 336 4.7E-59 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CIG75_RS13480 f9949a25cc6d309d945b56f7adb0fdf0 426 Gene3D G3DSA:3.65.10.10 21 219 2.9E-53 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CIG75_RS13480 f9949a25cc6d309d945b56f7adb0fdf0 426 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 3 415 3.6E-165 T 28-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CIG75_RS13480 f9949a25cc6d309d945b56f7adb0fdf0 426 Gene3D G3DSA:3.65.10.10 220 418 7.4E-43 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CIG75_RS13480 f9949a25cc6d309d945b56f7adb0fdf0 426 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 416 42.358 T 28-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CIG75_RS13480 f9949a25cc6d309d945b56f7adb0fdf0 426 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 404 4.4E-99 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CIG75_RS13480 f9949a25cc6d309d945b56f7adb0fdf0 426 SUPERFAMILY SSF55205 4 416 3.43E-130 T 28-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CIG75_RS16685 efdbb0263f9bf689d01faef45745dfbd 579 ProSitePatterns PS00211 ABC transporters family signature. 471 485 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS16685 efdbb0263f9bf689d01faef45745dfbd 579 Gene3D G3DSA:1.20.1560.10 2 321 5.9E-59 T 28-03-2018 CIG75_RS16685 efdbb0263f9bf689d01faef45745dfbd 579 SMART SM00382 359 545 8.6E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS16685 efdbb0263f9bf689d01faef45745dfbd 579 Pfam PF00005 ABC transporter 350 499 4.3E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS16685 efdbb0263f9bf689d01faef45745dfbd 579 SUPERFAMILY SSF52540 325 569 1.91E-85 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS16685 efdbb0263f9bf689d01faef45745dfbd 579 SUPERFAMILY SSF90123 8 317 6.67E-65 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CIG75_RS16685 efdbb0263f9bf689d01faef45745dfbd 579 Gene3D G3DSA:3.40.50.300 327 575 1.6E-76 T 28-03-2018 CIG75_RS16685 efdbb0263f9bf689d01faef45745dfbd 579 Pfam PF00664 ABC transporter transmembrane region 18 288 7.8E-46 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CIG75_RS13005 2492902085e6ee3fa730f76c2a23082a 209 Pfam PF00156 Phosphoribosyl transferase domain 48 154 2.7E-20 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CIG75_RS13005 2492902085e6ee3fa730f76c2a23082a 209 Gene3D G3DSA:3.40.50.2020 4 209 1.8E-38 T 28-03-2018 CIG75_RS13005 2492902085e6ee3fa730f76c2a23082a 209 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 209 28.888 T 28-03-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CIG75_RS13005 2492902085e6ee3fa730f76c2a23082a 209 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 12 180 1.4E-46 T 28-03-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CIG75_RS13005 2492902085e6ee3fa730f76c2a23082a 209 SUPERFAMILY SSF53271 10 208 4.06E-55 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CIG75_RS14495 0d5eae38bebc9083edcce74407710a8d 488 SUPERFAMILY SSF56322 14 475 3.14E-146 T 28-03-2018 IPR005801 ADC synthase GO:0009058 CIG75_RS14495 0d5eae38bebc9083edcce74407710a8d 488 Gene3D G3DSA:3.60.120.10 47 484 1.2E-160 T 28-03-2018 IPR005801 ADC synthase GO:0009058 CIG75_RS14495 0d5eae38bebc9083edcce74407710a8d 488 PRINTS PR00095 Anthranilate synthase component I signature 328 341 3.2E-20 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CIG75_RS14495 0d5eae38bebc9083edcce74407710a8d 488 PRINTS PR00095 Anthranilate synthase component I signature 314 327 3.2E-20 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CIG75_RS14495 0d5eae38bebc9083edcce74407710a8d 488 PRINTS PR00095 Anthranilate synthase component I signature 423 437 3.2E-20 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CIG75_RS14495 0d5eae38bebc9083edcce74407710a8d 488 PRINTS PR00095 Anthranilate synthase component I signature 408 422 3.2E-20 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CIG75_RS14495 0d5eae38bebc9083edcce74407710a8d 488 TIGRFAM TIGR01824 PabB-clade2: aminodeoxychorismate synthase, component I 112 470 5.5E-124 T 28-03-2018 IPR010118 Para-aminobenzoate synthase/anthranilate synthase, component I CIG75_RS14495 0d5eae38bebc9083edcce74407710a8d 488 Pfam PF00425 chorismate binding enzyme 213 466 2.9E-93 T 28-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal CIG75_RS14495 0d5eae38bebc9083edcce74407710a8d 488 Pfam PF04715 Anthranilate synthase component I, N terminal region 29 162 6.1E-30 T 28-03-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CIG75_RS11685 5e46aa02374e4fb74ab787df30854570 349 SUPERFAMILY SSF53822 42 263 5.89E-10 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CIG75_RS11685 5e46aa02374e4fb74ab787df30854570 349 Gene3D G3DSA:3.40.50.2300 160 343 1.3E-45 T 28-03-2018 CIG75_RS11685 5e46aa02374e4fb74ab787df30854570 349 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 45 337 8.1E-75 T 28-03-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 CIG75_RS11685 5e46aa02374e4fb74ab787df30854570 349 Gene3D G3DSA:3.40.50.2300 40 159 5.4E-37 T 28-03-2018 CIG75_RS14560 53fbfabaf2a2dd5b0597abecd1017c2b 166 Gene3D G3DSA:2.40.50.140 82 164 2.3E-15 T 28-03-2018 CIG75_RS14560 53fbfabaf2a2dd5b0597abecd1017c2b 166 Pfam PF01957 NfeD-like C-terminal, partner-binding 38 161 8.0E-8 T 28-03-2018 IPR002810 NfeD-like, C-terminal domain CIG75_RS14075 d5c85d6e14622bb6847209aae826a889 154 SUPERFAMILY SSF52499 1 131 7.85E-20 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CIG75_RS14075 d5c85d6e14622bb6847209aae826a889 154 Gene3D G3DSA:3.40.50.850 1 137 2.8E-20 T 28-03-2018 CIG75_RS14075 d5c85d6e14622bb6847209aae826a889 154 Pfam PF00857 Isochorismatase family 4 130 2.4E-14 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CIG75_RS02470 4e12d9ef7ba623fbff0dba3a663dce31 836 Gene3D G3DSA:3.40.50.300 1 816 3.8E-21 T 28-03-2018 CIG75_RS02470 4e12d9ef7ba623fbff0dba3a663dce31 836 SUPERFAMILY SSF52540 146 158 2.21E-16 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS02470 4e12d9ef7ba623fbff0dba3a663dce31 836 SUPERFAMILY SSF52540 2 116 2.21E-16 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS02470 4e12d9ef7ba623fbff0dba3a663dce31 836 SUPERFAMILY SSF52540 715 813 2.21E-16 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS02470 4e12d9ef7ba623fbff0dba3a663dce31 836 Pfam PF13476 AAA domain 7 251 4.2E-13 T 28-03-2018 CIG75_RS17270 d01826bc13d07db7836ba905463e84a5 414 Pfam PF05977 Transmembrane secretion effector 13 401 1.2E-18 T 28-03-2018 IPR010290 Transmembrane secretion effector CIG75_RS17270 d01826bc13d07db7836ba905463e84a5 414 Gene3D G3DSA:1.20.1250.20 3 204 5.2E-21 T 28-03-2018 CIG75_RS17270 d01826bc13d07db7836ba905463e84a5 414 Gene3D G3DSA:1.20.1250.20 214 411 1.9E-8 T 28-03-2018 CIG75_RS17270 d01826bc13d07db7836ba905463e84a5 414 SUPERFAMILY SSF103473 10 400 1.44E-35 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS17735 99b59637e213e5ad031176b2ffc3f937 120 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 5 118 18.144 T 28-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CIG75_RS17735 99b59637e213e5ad031176b2ffc3f937 120 TIGRFAM TIGR00494 crcB: protein CrcB 6 114 2.2E-25 T 28-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CIG75_RS17735 99b59637e213e5ad031176b2ffc3f937 120 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 7 113 2.7E-23 T 28-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CIG75_RS19840 2faff31743367d7a18b58c6b5537036a 222 Gene3D G3DSA:1.10.3130.10 1 61 3.2E-27 T 28-03-2018 CIG75_RS19840 2faff31743367d7a18b58c6b5537036a 222 SUPERFAMILY SSF51161 2 168 4.71E-57 T 28-03-2018 IPR011004 Trimeric LpxA-like CIG75_RS19840 2faff31743367d7a18b58c6b5537036a 222 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 117 151 1.1E-6 T 28-03-2018 IPR001451 Hexapeptide repeat CIG75_RS19840 2faff31743367d7a18b58c6b5537036a 222 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 72 108 1.7E-4 T 28-03-2018 IPR001451 Hexapeptide repeat CIG75_RS19840 2faff31743367d7a18b58c6b5537036a 222 PIRSF PIRSF000441 1 218 3.6E-86 T 28-03-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 CIG75_RS19840 2faff31743367d7a18b58c6b5537036a 222 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 5 166 3.5E-77 T 28-03-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 CIG75_RS19840 2faff31743367d7a18b58c6b5537036a 222 Gene3D G3DSA:2.160.10.10 62 220 1.8E-40 T 28-03-2018 CIG75_RS19840 2faff31743367d7a18b58c6b5537036a 222 Pfam PF06426 Serine acetyltransferase, N-terminal 3 35 3.1E-5 T 28-03-2018 IPR010493 Serine acetyltransferase, N-terminal GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 CIG75_RS17520 a04ea00101a1e1a81139c0be04ad4600 470 Pfam PF13421 SPFH domain-Band 7 family 52 274 1.4E-20 T 28-03-2018 IPR033880 SPFH domain, YdjI-like CIG75_RS17145 969daab3bb0288a959efea0f1d65f98c 103 Pfam PF06127 Protein of unknown function (DUF962) 6 91 1.9E-16 T 28-03-2018 IPR009305 Protein of unknown function DUF962 CIG75_RS16700 1ef5ac56114370c736bd785b648c0533 548 SUPERFAMILY SSF81442 17 527 2.09E-185 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CIG75_RS16700 1ef5ac56114370c736bd785b648c0533 548 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 29 473 5.9E-149 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CIG75_RS16700 1ef5ac56114370c736bd785b648c0533 548 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 249 303 - T 28-03-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CIG75_RS16700 1ef5ac56114370c736bd785b648c0533 548 PRINTS PR01165 Cytochrome c oxidase subunit I signature 247 268 3.0E-107 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CIG75_RS16700 1ef5ac56114370c736bd785b648c0533 548 PRINTS PR01165 Cytochrome c oxidase subunit I signature 20 45 3.0E-107 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CIG75_RS16700 1ef5ac56114370c736bd785b648c0533 548 PRINTS PR01165 Cytochrome c oxidase subunit I signature 67 90 3.0E-107 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CIG75_RS16700 1ef5ac56114370c736bd785b648c0533 548 PRINTS PR01165 Cytochrome c oxidase subunit I signature 353 371 3.0E-107 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CIG75_RS16700 1ef5ac56114370c736bd785b648c0533 548 PRINTS PR01165 Cytochrome c oxidase subunit I signature 95 119 3.0E-107 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CIG75_RS16700 1ef5ac56114370c736bd785b648c0533 548 PRINTS PR01165 Cytochrome c oxidase subunit I signature 167 185 3.0E-107 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CIG75_RS16700 1ef5ac56114370c736bd785b648c0533 548 PRINTS PR01165 Cytochrome c oxidase subunit I signature 431 452 3.0E-107 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CIG75_RS16700 1ef5ac56114370c736bd785b648c0533 548 PRINTS PR01165 Cytochrome c oxidase subunit I signature 196 215 3.0E-107 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CIG75_RS16700 1ef5ac56114370c736bd785b648c0533 548 PRINTS PR01165 Cytochrome c oxidase subunit I signature 381 400 3.0E-107 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CIG75_RS16700 1ef5ac56114370c736bd785b648c0533 548 PRINTS PR01165 Cytochrome c oxidase subunit I signature 317 338 3.0E-107 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CIG75_RS16700 1ef5ac56114370c736bd785b648c0533 548 PRINTS PR01165 Cytochrome c oxidase subunit I signature 137 149 3.0E-107 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CIG75_RS16700 1ef5ac56114370c736bd785b648c0533 548 PRINTS PR01165 Cytochrome c oxidase subunit I signature 293 308 3.0E-107 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CIG75_RS16700 1ef5ac56114370c736bd785b648c0533 548 Gene3D G3DSA:1.20.210.10 16 528 4.1E-205 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CIG75_RS16700 1ef5ac56114370c736bd785b648c0533 548 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 21 525 8.2E-216 T 28-03-2018 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005507|GO:0005886|GO:0006810|GO:0022900|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 CIG75_RS04780 701a4e1c244553115cefc1f3d32940ec 290 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 97 212 2.4E-28 T 28-03-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 CIG75_RS04780 701a4e1c244553115cefc1f3d32940ec 290 SUPERFAMILY SSF55166 93 221 8.37E-30 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CIG75_RS04780 701a4e1c244553115cefc1f3d32940ec 290 Gene3D G3DSA:3.30.1380.10 80 210 4.8E-27 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CIG75_RS19645 1fcdb9acaee84d20bde8815862caa14f 60 Gene3D G3DSA:3.30.1390.20 4 58 3.2E-24 T 28-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain CIG75_RS19645 1fcdb9acaee84d20bde8815862caa14f 60 ProSitePatterns PS00634 Ribosomal protein L30 signature. 22 54 - T 28-03-2018 IPR018038 Ribosomal protein L30, conserved site CIG75_RS19645 1fcdb9acaee84d20bde8815862caa14f 60 PIRSF PIRSF002211 1 60 1.4E-26 T 28-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS19645 1fcdb9acaee84d20bde8815862caa14f 60 SUPERFAMILY SSF55129 1 59 2.88E-21 T 28-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain CIG75_RS19645 1fcdb9acaee84d20bde8815862caa14f 60 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 4 55 1.1E-24 T 28-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS19645 1fcdb9acaee84d20bde8815862caa14f 60 Pfam PF00327 Ribosomal protein L30p/L7e 5 54 1.7E-19 T 28-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain CIG75_RS19645 1fcdb9acaee84d20bde8815862caa14f 60 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 1 58 18.886 T 28-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS08840 de0d8629758433dc13fce3af1f4efc46 184 Pfam PF09580 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) 78 176 2.5E-13 T 28-03-2018 IPR019076 Sporulation lipoprotein YhcN/YlaJ-like CIG75_RS05650 646632dfeb58e034bbf9cafe38b6b2f6 343 SUPERFAMILY SSF53335 174 324 3.28E-20 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CIG75_RS05650 646632dfeb58e034bbf9cafe38b6b2f6 343 Gene3D G3DSA:3.40.50.150 173 337 1.5E-26 T 28-03-2018 CIG75_RS05650 646632dfeb58e034bbf9cafe38b6b2f6 343 Pfam PF01728 FtsJ-like methyltransferase 182 276 2.9E-16 T 28-03-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 CIG75_RS04720 ed14b88a3300ecc5466fffbc867152bc 337 Gene3D G3DSA:3.40.1190.20 26 334 2.9E-46 T 28-03-2018 IPR029056 Ribokinase-like CIG75_RS04720 ed14b88a3300ecc5466fffbc867152bc 337 Pfam PF00294 pfkB family carbohydrate kinase 28 318 5.4E-51 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB CIG75_RS04720 ed14b88a3300ecc5466fffbc867152bc 337 PRINTS PR00990 Ribokinase signature 198 213 7.8E-6 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CIG75_RS04720 ed14b88a3300ecc5466fffbc867152bc 337 PRINTS PR00990 Ribokinase signature 56 75 7.8E-6 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CIG75_RS04720 ed14b88a3300ecc5466fffbc867152bc 337 PRINTS PR00990 Ribokinase signature 242 253 7.8E-6 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CIG75_RS04720 ed14b88a3300ecc5466fffbc867152bc 337 SUPERFAMILY SSF53613 27 320 2.34E-49 T 28-03-2018 IPR029056 Ribokinase-like CIG75_RS11680 1ad8c061a3dc88ae50d55d844a7f88a0 536 SMART SM00382 56 247 7.4E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS11680 1ad8c061a3dc88ae50d55d844a7f88a0 536 Gene3D G3DSA:3.40.50.300 277 520 5.7E-37 T 28-03-2018 CIG75_RS11680 1ad8c061a3dc88ae50d55d844a7f88a0 536 SUPERFAMILY SSF52540 282 516 2.57E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS11680 1ad8c061a3dc88ae50d55d844a7f88a0 536 Pfam PF00005 ABC transporter 300 456 4.1E-17 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS11680 1ad8c061a3dc88ae50d55d844a7f88a0 536 Pfam PF00005 ABC transporter 48 196 3.5E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS11680 1ad8c061a3dc88ae50d55d844a7f88a0 536 ProSitePatterns PS00211 ABC transporters family signature. 168 182 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS11680 1ad8c061a3dc88ae50d55d844a7f88a0 536 SUPERFAMILY SSF52540 31 247 1.36E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS11680 1ad8c061a3dc88ae50d55d844a7f88a0 536 Gene3D G3DSA:3.40.50.300 28 261 9.1E-50 T 28-03-2018 CIG75_RS04030 32b807e5e26d8cc8fb6abe36cc0a90fc 282 SUPERFAMILY SSF117396 3 265 5.75E-77 T 28-03-2018 IPR002763 Protein of unknown function DUF72 CIG75_RS04030 32b807e5e26d8cc8fb6abe36cc0a90fc 282 Gene3D G3DSA:3.20.20.410 1 278 2.2E-74 T 28-03-2018 IPR002763 Protein of unknown function DUF72 CIG75_RS04030 32b807e5e26d8cc8fb6abe36cc0a90fc 282 Pfam PF01904 Protein of unknown function DUF72 19 261 9.0E-57 T 28-03-2018 IPR002763 Protein of unknown function DUF72 CIG75_RS17935 fcf41c0bfcb65ed171e509a345d95ab8 116 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 4 110 1.9E-33 T 28-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 CIG75_RS17935 fcf41c0bfcb65ed171e509a345d95ab8 116 Gene3D G3DSA:2.30.30.110 1 116 1.4E-38 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CIG75_RS17935 fcf41c0bfcb65ed171e509a345d95ab8 116 SUPERFAMILY SSF50118 3 113 1.32E-41 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CIG75_RS17935 fcf41c0bfcb65ed171e509a345d95ab8 116 PIRSF PIRSF033490 1 113 1.2E-38 T 28-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 CIG75_RS01790 a1dc02d9a9fa78300ff03586db86d14b 65 PRINTS PR01249 Ribosomal protein L31 signature 30 45 7.9E-23 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS01790 a1dc02d9a9fa78300ff03586db86d14b 65 PRINTS PR01249 Ribosomal protein L31 signature 2 19 7.9E-23 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS01790 a1dc02d9a9fa78300ff03586db86d14b 65 PRINTS PR01249 Ribosomal protein L31 signature 45 63 7.9E-23 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS01790 a1dc02d9a9fa78300ff03586db86d14b 65 SUPERFAMILY SSF143800 1 64 1.49E-26 T 28-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS01790 a1dc02d9a9fa78300ff03586db86d14b 65 Hamap MF_00501 50S ribosomal protein L31 [rpmE]. 1 65 27.409 T 28-03-2018 IPR027491 Ribosomal protein L31 type A GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS01790 a1dc02d9a9fa78300ff03586db86d14b 65 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 64 1.6E-31 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS01790 a1dc02d9a9fa78300ff03586db86d14b 65 ProSitePatterns PS01143 Ribosomal protein L31 signature. 34 55 - T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS01790 a1dc02d9a9fa78300ff03586db86d14b 65 Pfam PF01197 Ribosomal protein L31 1 64 1.4E-31 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CIG75_RS16775 1050b61189f0b713f1cc67982ee0e137 410 Pfam PF13530 Sterol carrier protein domain 197 406 1.9E-28 T 28-03-2018 IPR025559 Enhanced intracellular survival protein domain CIG75_RS16775 1050b61189f0b713f1cc67982ee0e137 410 Pfam PF13527 Acetyltransferase (GNAT) domain 4 131 2.9E-19 T 28-03-2018 CIG75_RS16775 1050b61189f0b713f1cc67982ee0e137 410 SUPERFAMILY SSF55729 2 268 2.25E-36 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CIG75_RS16775 1050b61189f0b713f1cc67982ee0e137 410 Gene3D G3DSA:3.40.630.30 1 137 2.1E-8 T 28-03-2018 CIG75_RS16775 1050b61189f0b713f1cc67982ee0e137 410 Gene3D G3DSA:3.40.630.30 138 297 1.2E-16 T 28-03-2018 CIG75_RS16775 1050b61189f0b713f1cc67982ee0e137 410 Gene3D G3DSA:3.30.1050.10 298 403 9.6E-17 T 28-03-2018 IPR003033 SCP2 sterol-binding domain CIG75_RS16775 1050b61189f0b713f1cc67982ee0e137 410 SUPERFAMILY SSF55718 307 403 1.65E-14 T 28-03-2018 IPR003033 SCP2 sterol-binding domain CIG75_RS03255 b581ab1ebd0c6a9b947d2bf276c0cb09 265 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 1 264 17.846 T 28-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CIG75_RS03255 b581ab1ebd0c6a9b947d2bf276c0cb09 265 Pfam PF02673 Bacitracin resistance protein BacA 6 258 1.6E-82 T 28-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CIG75_RS03255 b581ab1ebd0c6a9b947d2bf276c0cb09 265 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 6 257 1.9E-88 T 28-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CIG75_RS15565 c8629817da5e75d32545716c7f31bce1 200 Pfam PF02660 Glycerol-3-phosphate acyltransferase 16 189 2.6E-50 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CIG75_RS15565 c8629817da5e75d32545716c7f31bce1 200 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 10 199 8.2E-64 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CIG75_RS15565 c8629817da5e75d32545716c7f31bce1 200 SMART SM01207 15 190 4.8E-75 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CIG75_RS15565 c8629817da5e75d32545716c7f31bce1 200 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 12 198 20.186 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CIG75_RS15480 d05732e3cadac5ebb809a94ea313eaf6 140 SUPERFAMILY SSF51735 3 134 3.24E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS15480 d05732e3cadac5ebb809a94ea313eaf6 140 Gene3D G3DSA:3.40.50.720 14 136 2.6E-32 T 28-03-2018 CIG75_RS15480 d05732e3cadac5ebb809a94ea313eaf6 140 Pfam PF13380 CoA binding domain 18 132 5.1E-40 T 28-03-2018 IPR003781 CoA-binding GO:0048037 CIG75_RS15480 d05732e3cadac5ebb809a94ea313eaf6 140 SMART SM00881 13 106 2.9E-20 T 28-03-2018 IPR003781 CoA-binding GO:0048037 CIG75_RS12830 f6b30986faebcb811b1a8ee791b20313 189 Pfam PF02195 ParB-like nuclease domain 9 95 2.6E-11 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CIG75_RS12830 f6b30986faebcb811b1a8ee791b20313 189 SMART SM00470 7 96 1.2E-6 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CIG75_RS12830 f6b30986faebcb811b1a8ee791b20313 189 Gene3D G3DSA:3.90.1530.10 1 98 1.1E-15 T 28-03-2018 CIG75_RS12830 f6b30986faebcb811b1a8ee791b20313 189 SUPERFAMILY SSF110849 6 96 7.85E-15 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CIG75_RS02775 6bb13c8cb3562230a5747131d9749648 327 SUPERFAMILY SSF52540 2 229 6.78E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS02775 6bb13c8cb3562230a5747131d9749648 327 Pfam PF00005 ABC transporter 23 166 2.9E-22 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS02775 6bb13c8cb3562230a5747131d9749648 327 Gene3D G3DSA:3.40.50.300 1 255 2.0E-50 T 28-03-2018 CIG75_RS02775 6bb13c8cb3562230a5747131d9749648 327 SMART SM00382 31 214 3.5E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS00330 b86841e689e7ed0001d42b8002e4b512 295 Gene3D G3DSA:3.30.70.100 181 276 5.0E-15 T 28-03-2018 CIG75_RS00330 b86841e689e7ed0001d42b8002e4b512 295 SUPERFAMILY SSF82861 25 112 8.11E-17 T 28-03-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 CIG75_RS00330 b86841e689e7ed0001d42b8002e4b512 295 SUPERFAMILY SSF82689 181 280 5.89E-17 T 28-03-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 CIG75_RS00330 b86841e689e7ed0001d42b8002e4b512 295 Pfam PF00924 Mechanosensitive ion channel 71 271 3.8E-43 T 28-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 CIG75_RS00330 b86841e689e7ed0001d42b8002e4b512 295 SUPERFAMILY SSF50182 114 180 3.92E-12 T 28-03-2018 IPR010920 LSM domain CIG75_RS00330 b86841e689e7ed0001d42b8002e4b512 295 Gene3D G3DSA:2.30.30.60 129 180 1.3E-11 T 28-03-2018 CIG75_RS07610 5dea4fe9d6e7feb2486d4e524c2de5c5 238 Pfam PF13386 Cytochrome C biogenesis protein transmembrane region 34 221 1.1E-9 T 28-03-2018 CIG75_RS07610 5dea4fe9d6e7feb2486d4e524c2de5c5 238 Gene3D G3DSA:1.20.1250.20 31 229 1.3E-4 T 28-03-2018 CIG75_RS17525 1fac2036081de3ce2379a9af982a0b82 262 Pfam PF04536 TPM domain 27 147 5.7E-32 T 28-03-2018 IPR007621 TPM domain CIG75_RS10860 c00b9abe6067faadf1ff965bc8e28f2d 206 Gene3D G3DSA:3.40.50.150 48 189 2.8E-17 T 28-03-2018 CIG75_RS10860 c00b9abe6067faadf1ff965bc8e28f2d 206 SUPERFAMILY SSF53335 31 193 2.74E-19 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CIG75_RS10860 c00b9abe6067faadf1ff965bc8e28f2d 206 Pfam PF13649 Methyltransferase domain 68 165 2.7E-9 T 28-03-2018 CIG75_RS09655 56e0870788c8bde69ef22e543c7f65b4 362 Pfam PF04055 Radical SAM superfamily 66 232 1.9E-16 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CIG75_RS09655 56e0870788c8bde69ef22e543c7f65b4 362 Hamap MF_00992 Cyclic dehypoxanthine futalosine synthase [mqnC]. 21 362 49.286 T 28-03-2018 IPR022431 Cyclic dehypoxanthine futalosine synthase GO:0009234 KEGG: 00130+1.21.98.1|MetaCyc: PWY-7371|MetaCyc: PWY-7374 CIG75_RS09655 56e0870788c8bde69ef22e543c7f65b4 362 PIRSF PIRSF004762 1 361 5.6E-103 T 28-03-2018 CIG75_RS09655 56e0870788c8bde69ef22e543c7f65b4 362 TIGRFAM TIGR03699 menaquin_MqnC: dehypoxanthine futalosine cyclase 22 359 5.8E-144 T 28-03-2018 IPR022431 Cyclic dehypoxanthine futalosine synthase GO:0009234 KEGG: 00130+1.21.98.1|MetaCyc: PWY-7371|MetaCyc: PWY-7374 CIG75_RS09655 56e0870788c8bde69ef22e543c7f65b4 362 Gene3D G3DSA:3.20.20.70 2 361 1.5E-50 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CIG75_RS09655 56e0870788c8bde69ef22e543c7f65b4 362 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 59 359 7.6E-108 T 28-03-2018 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 CIG75_RS09655 56e0870788c8bde69ef22e543c7f65b4 362 SUPERFAMILY SSF102114 21 352 4.45E-49 T 28-03-2018 CIG75_RS16175 e3494398481aec330d199a029f9bfa9e 152 Gene3D G3DSA:3.10.129.10 8 148 8.7E-36 T 28-03-2018 CIG75_RS16175 e3494398481aec330d199a029f9bfa9e 152 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 15 131 6.9E-20 T 28-03-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 CIG75_RS16175 e3494398481aec330d199a029f9bfa9e 152 PIRSF PIRSF003230 6 147 6.5E-20 T 28-03-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 CIG75_RS16175 e3494398481aec330d199a029f9bfa9e 152 Pfam PF13279 Thioesterase-like superfamily 18 138 2.5E-17 T 28-03-2018 CIG75_RS16175 e3494398481aec330d199a029f9bfa9e 152 SUPERFAMILY SSF54637 12 142 3.32E-35 T 28-03-2018 IPR029069 HotDog domain CIG75_RS04730 9efdddaca19dffbe2ec0e2f8a36e0a07 200 Pfam PF05257 CHAP domain 61 158 2.9E-11 T 28-03-2018 IPR007921 CHAP domain CIG75_RS04730 9efdddaca19dffbe2ec0e2f8a36e0a07 200 SUPERFAMILY SSF54001 53 169 2.16E-17 T 28-03-2018 CIG75_RS07770 79a6b9931a15a8548e54f4eca34f7da6 146 Gene3D G3DSA:3.90.79.10 2 141 1.2E-23 T 28-03-2018 CIG75_RS07770 79a6b9931a15a8548e54f4eca34f7da6 146 SUPERFAMILY SSF55811 6 137 5.82E-25 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CIG75_RS07770 79a6b9931a15a8548e54f4eca34f7da6 146 Pfam PF00293 NUDIX domain 9 119 5.7E-17 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CIG75_RS07770 79a6b9931a15a8548e54f4eca34f7da6 146 ProSitePatterns PS00893 Nudix box signature. 40 61 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CIG75_RS04645 0345fc8f2767203de707212dd5b1cf4b 224 Pfam PF04140 Isoprenylcysteine carboxyl methyltransferase (ICMT) family 114 203 3.8E-29 T 28-03-2018 IPR007269 Isoprenylcysteine carboxyl methyltransferase GO:0004671|GO:0006481|GO:0016021 Reactome: R-HSA-163841 CIG75_RS14740 e50501afe22278733da11e4a61d600f2 399 Pfam PF06898 Putative stage IV sporulation protein YqfD 9 385 4.1E-109 T 28-03-2018 IPR010690 Putative stage IV sporulation YqfD CIG75_RS14740 e50501afe22278733da11e4a61d600f2 399 PIRSF PIRSF029895 1 396 1.3E-98 T 28-03-2018 IPR010690 Putative stage IV sporulation YqfD CIG75_RS14740 e50501afe22278733da11e4a61d600f2 399 TIGRFAM TIGR02876 spore_yqfD: sporulation protein YqfD 7 387 3.0E-93 T 28-03-2018 IPR010690 Putative stage IV sporulation YqfD CIG75_RS00210 c393e71c23c5ab89ba4cde5c43e83ca4 73 Gene3D G3DSA:3.10.290.10 2 72 3.8E-10 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CIG75_RS00210 c393e71c23c5ab89ba4cde5c43e83ca4 73 TIGRFAM TIGR02988 YaaA_near_RecF: S4 domain protein YaaA 5 63 6.5E-28 T 28-03-2018 IPR014330 RNA-binding S4-related,YaaA CIG75_RS00210 c393e71c23c5ab89ba4cde5c43e83ca4 73 SUPERFAMILY SSF55174 3 67 4.54E-18 T 28-03-2018 CIG75_RS00210 c393e71c23c5ab89ba4cde5c43e83ca4 73 Pfam PF13275 S4 domain 6 70 1.2E-26 T 28-03-2018 CIG75_RS02080 b551d7dec9e654567de79cbe2a61ce7b 219 Pfam PF01205 Uncharacterized protein family UPF0029 19 122 2.1E-35 T 28-03-2018 IPR001498 Impact, N-terminal CIG75_RS02080 b551d7dec9e654567de79cbe2a61ce7b 219 SUPERFAMILY SSF54211 3 130 1.9E-44 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CIG75_RS02080 b551d7dec9e654567de79cbe2a61ce7b 219 ProSitePatterns PS00910 Uncharacterized protein family UPF0029 signature. 79 108 - T 28-03-2018 IPR020569 Uncharacterised protein family UPF0029, Impact, conserved site CIG75_RS02080 b551d7dec9e654567de79cbe2a61ce7b 219 Gene3D G3DSA:3.30.70.240 135 199 7.2E-16 T 28-03-2018 CIG75_RS02080 b551d7dec9e654567de79cbe2a61ce7b 219 Gene3D G3DSA:3.30.230.30 4 133 3.0E-49 T 28-03-2018 IPR001498 Impact, N-terminal CIG75_RS02080 b551d7dec9e654567de79cbe2a61ce7b 219 Pfam PF09186 Domain of unknown function (DUF1949) 140 196 2.3E-13 T 28-03-2018 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal CIG75_RS02080 b551d7dec9e654567de79cbe2a61ce7b 219 TIGRFAM TIGR00257 IMPACT_YIGZ: uncharacterized protein, YigZ family 3 203 1.4E-60 T 28-03-2018 IPR015796 Impact family, bacterial/archaeal CIG75_RS02080 b551d7dec9e654567de79cbe2a61ce7b 219 SUPERFAMILY SSF54980 136 203 1.26E-9 T 28-03-2018 IPR035647 EF-G domain III/V-like CIG75_RS03390 de623fe5802fc5e191108dd16fa0f075 602 Gene3D G3DSA:1.20.1560.10 1 340 1.9E-36 T 28-03-2018 CIG75_RS03390 de623fe5802fc5e191108dd16fa0f075 602 Pfam PF00664 ABC transporter transmembrane region 64 304 9.6E-20 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CIG75_RS03390 de623fe5802fc5e191108dd16fa0f075 602 Gene3D G3DSA:3.40.50.300 358 602 2.0E-54 T 28-03-2018 CIG75_RS03390 de623fe5802fc5e191108dd16fa0f075 602 SMART SM00382 396 575 2.0E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS03390 de623fe5802fc5e191108dd16fa0f075 602 SUPERFAMILY SSF90123 36 340 5.62E-42 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CIG75_RS03390 de623fe5802fc5e191108dd16fa0f075 602 Pfam PF00005 ABC transporter 388 527 4.0E-19 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS03390 de623fe5802fc5e191108dd16fa0f075 602 SUPERFAMILY SSF52540 371 599 2.52E-49 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS16940 0ab88baa8caf1379f5fdda96c81551ec 261 TIGRFAM TIGR00715 precor6x_red: precorrin-6x reductase 2 251 4.0E-63 T 28-03-2018 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 CIG75_RS16940 0ab88baa8caf1379f5fdda96c81551ec 261 Pfam PF02571 Precorrin-6x reductase CbiJ/CobK 2 250 2.0E-78 T 28-03-2018 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 CIG75_RS16940 0ab88baa8caf1379f5fdda96c81551ec 261 Gene3D G3DSA:3.40.50.2300 63 259 4.9E-11 T 28-03-2018 CIG75_RS11875 57f306baf734d610263b1dfa80e60dbc 257 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 27 254 1.7E-91 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CIG75_RS11875 57f306baf734d610263b1dfa80e60dbc 257 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 200 217 - T 28-03-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199 CIG75_RS11875 57f306baf734d610263b1dfa80e60dbc 257 Pfam PF01255 Putative undecaprenyl diphosphate synthase 34 254 8.8E-85 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CIG75_RS11875 57f306baf734d610263b1dfa80e60dbc 257 Gene3D G3DSA:3.40.1180.10 14 257 1.6E-97 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CIG75_RS11875 57f306baf734d610263b1dfa80e60dbc 257 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 27 255 41.853 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CIG75_RS11875 57f306baf734d610263b1dfa80e60dbc 257 SUPERFAMILY SSF64005 24 249 5.62E-91 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CIG75_RS12025 9d1b0a49941ab6edf7549fa7457e6f8e 124 TIGRFAM TIGR02530 flg_new: flagellar operon protein 28 122 9.9E-30 T 28-03-2018 IPR013367 Flagellar, putative CIG75_RS12025 9d1b0a49941ab6edf7549fa7457e6f8e 124 Pfam PF12611 Putative flagellar 100 123 5.2E-11 T 28-03-2018 IPR013367 Flagellar, putative CIG75_RS19245 4b6ce692c3dd65cc1c12b678de608c19 63 Gene3D G3DSA:1.10.3100.10 2 62 4.0E-17 T 28-03-2018 IPR027910 YdiL-like domain CIG75_RS19245 4b6ce692c3dd65cc1c12b678de608c19 63 SUPERFAMILY SSF47413 1 60 1.52E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CIG75_RS19245 4b6ce692c3dd65cc1c12b678de608c19 63 SMART SM00530 6 60 1.5E-15 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS19245 4b6ce692c3dd65cc1c12b678de608c19 63 Pfam PF01381 Helix-turn-helix 7 59 1.8E-16 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS13980 637ba5552d00db2cccd06d45489f090d 263 SUPERFAMILY SSF53335 34 241 1.16E-40 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CIG75_RS13980 637ba5552d00db2cccd06d45489f090d 263 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 143 157 - T 28-03-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 CIG75_RS13980 637ba5552d00db2cccd06d45489f090d 263 Gene3D G3DSA:3.40.50.150 25 254 2.2E-34 T 28-03-2018 CIG75_RS13980 637ba5552d00db2cccd06d45489f090d 263 Pfam PF13649 Methyltransferase domain 57 149 2.1E-24 T 28-03-2018 CIG75_RS07570 0653f000dc5c32ffec2598ac34d27c69 152 Pfam PF01475 Ferric uptake regulator family 16 133 4.0E-31 T 28-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CIG75_RS07570 0653f000dc5c32ffec2598ac34d27c69 152 SUPERFAMILY SSF46785 10 137 5.27E-37 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS07570 0653f000dc5c32ffec2598ac34d27c69 152 Gene3D G3DSA:1.10.10.10 9 93 2.9E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS06080 c0de6226d20b21f3e255d982bc804d65 138 Gene3D G3DSA:2.60.40.10 28 135 4.4E-7 T 28-03-2018 IPR013783 Immunoglobulin-like fold CIG75_RS06080 c0de6226d20b21f3e255d982bc804d65 138 SUPERFAMILY SSF49373 60 122 7.45E-5 T 28-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments CIG75_RS16965 a1a84ad4b991859098b25c770268b8c3 344 Gene3D G3DSA:3.40.710.10 4 343 1.1E-52 T 28-03-2018 CIG75_RS16965 a1a84ad4b991859098b25c770268b8c3 344 Pfam PF00144 Beta-lactamase 18 328 2.8E-40 T 28-03-2018 IPR001466 Beta-lactamase-related CIG75_RS16965 a1a84ad4b991859098b25c770268b8c3 344 SUPERFAMILY SSF56601 9 327 1.78E-59 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CIG75_RS09315 2304f8ba62c8a2ff937d325fba54ef76 255 PIRSF PIRSF016933 30 251 7.5E-66 T 28-03-2018 IPR023596 Peptidase PrsW, archaeal/bacterial GO:0008233 CIG75_RS09315 2304f8ba62c8a2ff937d325fba54ef76 255 Pfam PF13367 Protease prsW family 57 228 4.8E-33 T 28-03-2018 IPR026898 Protease PrsW GO:0008233 CIG75_RS01075 7a4f6ea2608ad53666dafd10ea3e4add 178 SUPERFAMILY SSF88874 1 172 1.57E-46 T 28-03-2018 CIG75_RS01075 7a4f6ea2608ad53666dafd10ea3e4add 178 Pfam PF07484 Phage Tail Collar Domain 7 62 1.6E-25 T 28-03-2018 IPR011083 Phage tail collar domain CIG75_RS01075 7a4f6ea2608ad53666dafd10ea3e4add 178 Gene3D G3DSA:3.90.1340.10 1 66 4.9E-21 T 28-03-2018 IPR011083 Phage tail collar domain CIG75_RS05265 59bc47a9ad9490c0a0280a3db868e146 104 Pfam PF11023 Zinc-ribbon containing domain 2 87 4.9E-25 T 28-03-2018 IPR020912 Uncharacterised protein family UPF0295 GO:0005887 CIG75_RS05265 59bc47a9ad9490c0a0280a3db868e146 104 ProDom PD355753 MEMBRANE TRANSMEMBRANE UPF0295 BLI00901/BL05075 BT9727_0449 GK0479 BCE0593 YGZB PRECURSOR BA0538/GBAA0538/BAS0506 2 94 7.0E-16 T 28-03-2018 IPR020912 Uncharacterised protein family UPF0295 GO:0005887 CIG75_RS09945 d925bbc9b3a8e007441bb445e358e02a 309 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 12 262 1.3E-74 T 28-03-2018 IPR014145 DNA ligase D, polymerase domain CIG75_RS09150 ab5ad37cb8aad878cb0c44c95d331da4 416 SUPERFAMILY SSF144091 213 384 6.93E-44 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CIG75_RS09150 ab5ad37cb8aad878cb0c44c95d331da4 416 Gene3D G3DSA:1.20.1540.10 208 385 1.6E-39 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CIG75_RS09150 ab5ad37cb8aad878cb0c44c95d331da4 416 Pfam PF01694 Rhomboid family 248 382 1.1E-36 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CIG75_RS06395 2649821611b49fc62900871242b83381 291 Gene3D G3DSA:1.20.1640.10 55 291 3.1E-28 T 28-03-2018 CIG75_RS06395 2649821611b49fc62900871242b83381 291 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 51 273 2.5E-49 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CIG75_RS06395 2649821611b49fc62900871242b83381 291 SUPERFAMILY SSF82866 104 289 7.32E-35 T 28-03-2018 CIG75_RS06395 2649821611b49fc62900871242b83381 291 Pfam PF02355 Protein export membrane protein 106 285 3.6E-57 T 28-03-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial CIG75_RS06395 2649821611b49fc62900871242b83381 291 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 31 276 3.0E-64 T 28-03-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 CIG75_RS06395 2649821611b49fc62900871242b83381 291 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 3 287 25.505 T 28-03-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 CIG75_RS06395 2649821611b49fc62900871242b83381 291 PRINTS PR01755 Bacterial translocase SecF protein signature 189 207 1.2E-25 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CIG75_RS06395 2649821611b49fc62900871242b83381 291 PRINTS PR01755 Bacterial translocase SecF protein signature 30 45 1.2E-25 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CIG75_RS06395 2649821611b49fc62900871242b83381 291 PRINTS PR01755 Bacterial translocase SecF protein signature 224 239 1.2E-25 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CIG75_RS06395 2649821611b49fc62900871242b83381 291 PRINTS PR01755 Bacterial translocase SecF protein signature 141 155 1.2E-25 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CIG75_RS15300 2400934a32095bc825a901168c83733b 376 SUPERFAMILY SSF103473 1 366 7.72E-71 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS15300 2400934a32095bc825a901168c83733b 376 PRINTS PR01035 Tetracycline resistance protein signature 228 248 1.5E-35 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CIG75_RS15300 2400934a32095bc825a901168c83733b 376 PRINTS PR01035 Tetracycline resistance protein signature 256 277 1.5E-35 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CIG75_RS15300 2400934a32095bc825a901168c83733b 376 PRINTS PR01035 Tetracycline resistance protein signature 146 166 1.5E-35 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CIG75_RS15300 2400934a32095bc825a901168c83733b 376 PRINTS PR01035 Tetracycline resistance protein signature 3 19 1.5E-35 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CIG75_RS15300 2400934a32095bc825a901168c83733b 376 PRINTS PR01035 Tetracycline resistance protein signature 118 140 1.5E-35 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CIG75_RS15300 2400934a32095bc825a901168c83733b 376 PRINTS PR01035 Tetracycline resistance protein signature 60 84 1.5E-35 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CIG75_RS15300 2400934a32095bc825a901168c83733b 376 PRINTS PR01035 Tetracycline resistance protein signature 316 339 1.5E-35 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CIG75_RS15300 2400934a32095bc825a901168c83733b 376 Gene3D G3DSA:1.20.1250.20 187 375 1.2E-21 T 28-03-2018 CIG75_RS15300 2400934a32095bc825a901168c83733b 376 Pfam PF07690 Major Facilitator Superfamily 2 309 1.2E-54 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CIG75_RS15300 2400934a32095bc825a901168c83733b 376 Gene3D G3DSA:1.20.1250.20 1 184 3.7E-41 T 28-03-2018 CIG75_RS19100 60e972a2672a8eb687eecb1419570dd5 380 Gene3D G3DSA:3.20.20.105 221 373 0.0013 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CIG75_RS19100 60e972a2672a8eb687eecb1419570dd5 380 Gene3D G3DSA:3.20.20.105 128 213 0.14 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CIG75_RS19100 60e972a2672a8eb687eecb1419570dd5 380 SUPERFAMILY SSF51713 143 346 1.96E-7 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CIG75_RS00370 76ba40c648c8011a35c9af5d1a4ec51a 219 Pfam PF00436 Single-strand binding protein family 2 103 3.7E-36 T 28-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 CIG75_RS00370 76ba40c648c8011a35c9af5d1a4ec51a 219 Gene3D G3DSA:2.40.50.140 1 110 1.8E-39 T 28-03-2018 CIG75_RS00370 76ba40c648c8011a35c9af5d1a4ec51a 219 SUPERFAMILY SSF50249 1 159 1.34E-48 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CIG75_RS00370 76ba40c648c8011a35c9af5d1a4ec51a 219 Hamap MF_00984 Single-stranded DNA-binding protein. 2 107 33.339 T 28-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CIG75_RS00370 76ba40c648c8011a35c9af5d1a4ec51a 219 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 1 219 2.5E-41 T 28-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CIG75_RS06905 e77f19e6a2b5e64fca975cfd253c0672 377 SUPERFAMILY SSF53383 1 373 3.5E-108 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CIG75_RS06905 e77f19e6a2b5e64fca975cfd253c0672 377 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 191 210 - T 28-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site CIG75_RS06905 e77f19e6a2b5e64fca975cfd253c0672 377 Gene3D G3DSA:3.90.1150.10 261 377 3.5E-32 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CIG75_RS06905 e77f19e6a2b5e64fca975cfd253c0672 377 Pfam PF00266 Aminotransferase class-V 2 361 6.9E-86 T 28-03-2018 IPR000192 Aminotransferase class V domain CIG75_RS06905 e77f19e6a2b5e64fca975cfd253c0672 377 PIRSF PIRSF005572 1 377 3.6E-129 T 28-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CIG75_RS06905 e77f19e6a2b5e64fca975cfd253c0672 377 Gene3D G3DSA:3.40.640.10 10 254 3.8E-60 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CIG75_RS02345 c7a15fbfbe7870042d32c01193cd726b 166 Gene3D G3DSA:1.20.58.300 2 135 1.9E-20 T 28-03-2018 CIG75_RS02345 c7a15fbfbe7870042d32c01193cd726b 166 SUPERFAMILY SSF140566 7 134 1.23E-15 T 28-03-2018 IPR007809 FlgN-like protein GO:0005515|GO:0044780 CIG75_RS02345 c7a15fbfbe7870042d32c01193cd726b 166 Pfam PF05130 FlgN protein 4 147 1.5E-17 T 28-03-2018 IPR007809 FlgN-like protein GO:0005515|GO:0044780 CIG75_RS12560 e0e4ad216068d2a3b8d726b5896cbcdf 523 SUPERFAMILY SSF51430 43 127 1.96E-34 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CIG75_RS12560 e0e4ad216068d2a3b8d726b5896cbcdf 523 SUPERFAMILY SSF51430 158 314 1.96E-34 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CIG75_RS12560 e0e4ad216068d2a3b8d726b5896cbcdf 523 Pfam PF00248 Aldo/keto reductase family 66 239 6.4E-20 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CIG75_RS12560 e0e4ad216068d2a3b8d726b5896cbcdf 523 Gene3D G3DSA:3.20.20.100 42 522 9.0E-58 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CIG75_RS05895 bcf2194ac684a6b25da0f1b9faf47c38 129 Pfam PF17428 Family of unknown function (DUF5412) 11 127 3.7E-46 T 28-03-2018 IPR035406 Protein of unknown function DUF5412 CIG75_RS14970 311343eb6ec041ed35b9b3083ae3bdb7 235 Gene3D G3DSA:3.90.79.10 1 220 2.5E-24 T 28-03-2018 CIG75_RS14970 311343eb6ec041ed35b9b3083ae3bdb7 235 SUPERFAMILY SSF55811 134 203 3.66E-15 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CIG75_RS14970 311343eb6ec041ed35b9b3083ae3bdb7 235 SUPERFAMILY SSF55811 11 92 3.66E-15 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CIG75_RS16690 2c5016a257e9f4108570b165f3a7bed2 210 Gene3D G3DSA:1.20.120.80 15 194 7.9E-10 T 28-03-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CIG75_RS16690 2c5016a257e9f4108570b165f3a7bed2 210 SUPERFAMILY SSF81452 12 122 2.22E-6 T 28-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CIG75_RS16750 a55221d913505b15c71001daffc38c86 181 SUPERFAMILY SSF55729 9 174 2.48E-44 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CIG75_RS16750 a55221d913505b15c71001daffc38c86 181 Pfam PF13302 Acetyltransferase (GNAT) domain 11 149 1.0E-21 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CIG75_RS16750 a55221d913505b15c71001daffc38c86 181 Gene3D G3DSA:3.40.630.30 5 181 1.9E-28 T 28-03-2018 CIG75_RS16610 a06733f26622356db4969f3c4bb3c08f 193 PIRSF PIRSF037394 1 192 2.2E-57 T 28-03-2018 IPR017195 ABC-type thiamin-related transport system, permease component 1, predicted CIG75_RS16610 a06733f26622356db4969f3c4bb3c08f 193 Pfam PF09819 ABC-type cobalt transport system, permease component 10 127 2.9E-35 T 28-03-2018 IPR017195 ABC-type thiamin-related transport system, permease component 1, predicted CIG75_RS12875 de62c46e5fed151c41d8b0e3f77e871c 285 SUPERFAMILY SSF46785 180 232 7.89E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS12875 de62c46e5fed151c41d8b0e3f77e871c 285 Pfam PF09397 Ftsk gamma domain 183 232 1.3E-7 T 28-03-2018 IPR018541 FtsK gamma domain CIG75_RS12875 de62c46e5fed151c41d8b0e3f77e871c 285 Gene3D G3DSA:1.10.10.10 180 232 7.3E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS00735 a328dcf04ab4df06f299bed61c3f112a 147 SUPERFAMILY SSF52518 1 121 2.36E-28 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CIG75_RS00735 a328dcf04ab4df06f299bed61c3f112a 147 Gene3D G3DSA:3.40.50.970 1 104 1.6E-21 T 28-03-2018 CIG75_RS00735 a328dcf04ab4df06f299bed61c3f112a 147 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 1 88 2.3E-17 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CIG75_RS05715 35d7a2c123a609c6fa310d4ec07d2cd6 91 Gene3D G3DSA:3.40.50.2000 1 71 5.6E-15 T 28-03-2018 CIG75_RS05715 35d7a2c123a609c6fa310d4ec07d2cd6 91 SUPERFAMILY SSF53756 2 81 2.08E-21 T 28-03-2018 CIG75_RS05715 35d7a2c123a609c6fa310d4ec07d2cd6 91 Pfam PF00534 Glycosyl transferases group 1 1 57 5.8E-9 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CIG75_RS15880 f668d37ab29bf500559176b71a9d363b 185 Gene3D G3DSA:3.90.1140.10 1 185 2.2E-31 T 28-03-2018 CIG75_RS15880 f668d37ab29bf500559176b71a9d363b 185 SUPERFAMILY SSF55144 3 182 9.07E-32 T 28-03-2018 IPR009097 Cyclic phosphodiesterase CIG75_RS15880 f668d37ab29bf500559176b71a9d363b 185 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 3 181 4.7E-30 T 28-03-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 CIG75_RS15880 f668d37ab29bf500559176b71a9d363b 185 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 2 182 19.348 T 28-03-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 CIG75_RS15880 f668d37ab29bf500559176b71a9d363b 185 Pfam PF13563 2'-5' RNA ligase superfamily 32 163 5.6E-11 T 28-03-2018 CIG75_RS09015 d8df1179b7282f30e9c4a7b692fe9b8f 80 Gene3D G3DSA:2.20.25.10 1 50 0.078 T 28-03-2018 CIG75_RS05625 4df2b92749725fc36eb7b2e56ba36669 201 SUPERFAMILY SSF52540 1 196 8.18E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS05625 4df2b92749725fc36eb7b2e56ba36669 201 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 2 189 6.9E-59 T 28-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 CIG75_RS05625 4df2b92749725fc36eb7b2e56ba36669 201 Pfam PF01121 Dephospho-CoA kinase 1 182 2.3E-61 T 28-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 CIG75_RS05625 4df2b92749725fc36eb7b2e56ba36669 201 Gene3D G3DSA:3.40.50.300 1 200 2.5E-52 T 28-03-2018 CIG75_RS05625 4df2b92749725fc36eb7b2e56ba36669 201 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 1 198 28.086 T 28-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 CIG75_RS12145 4de756f9f231551c724b0b2737ecac1a 409 Pfam PF07690 Major Facilitator Superfamily 11 251 5.9E-38 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CIG75_RS12145 4de756f9f231551c724b0b2737ecac1a 409 Gene3D G3DSA:1.20.1250.20 1 204 1.8E-39 T 28-03-2018 CIG75_RS12145 4de756f9f231551c724b0b2737ecac1a 409 SUPERFAMILY SSF103473 5 396 2.88E-76 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS12145 4de756f9f231551c724b0b2737ecac1a 409 Gene3D G3DSA:1.20.1250.20 205 409 2.2E-32 T 28-03-2018 CIG75_RS12145 4de756f9f231551c724b0b2737ecac1a 409 PRINTS PR01035 Tetracycline resistance protein signature 281 302 7.2E-11 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CIG75_RS12145 4de756f9f231551c724b0b2737ecac1a 409 PRINTS PR01035 Tetracycline resistance protein signature 17 33 7.2E-11 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CIG75_RS12145 4de756f9f231551c724b0b2737ecac1a 409 PRINTS PR01035 Tetracycline resistance protein signature 106 127 7.2E-11 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CIG75_RS12145 4de756f9f231551c724b0b2737ecac1a 409 PRINTS PR01035 Tetracycline resistance protein signature 136 158 7.2E-11 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CIG75_RS12145 4de756f9f231551c724b0b2737ecac1a 409 PRINTS PR01035 Tetracycline resistance protein signature 79 103 7.2E-11 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CIG75_RS14155 4de53accfd3d711c52a9cc61cf0dfcac 193 Pfam PF00117 Glutamine amidotransferase class-I 3 185 1.4E-54 T 28-03-2018 IPR017926 Glutamine amidotransferase CIG75_RS14155 4de53accfd3d711c52a9cc61cf0dfcac 193 PRINTS PR00097 Anthranilate synthase component II signature 47 56 2.3E-36 T 28-03-2018 CIG75_RS14155 4de53accfd3d711c52a9cc61cf0dfcac 193 PRINTS PR00097 Anthranilate synthase component II signature 99 107 2.3E-36 T 28-03-2018 CIG75_RS14155 4de53accfd3d711c52a9cc61cf0dfcac 193 PRINTS PR00097 Anthranilate synthase component II signature 74 85 2.3E-36 T 28-03-2018 CIG75_RS14155 4de53accfd3d711c52a9cc61cf0dfcac 193 PRINTS PR00097 Anthranilate synthase component II signature 2 16 2.3E-36 T 28-03-2018 CIG75_RS14155 4de53accfd3d711c52a9cc61cf0dfcac 193 PRINTS PR00097 Anthranilate synthase component II signature 119 131 2.3E-36 T 28-03-2018 CIG75_RS14155 4de53accfd3d711c52a9cc61cf0dfcac 193 PRINTS PR00097 Anthranilate synthase component II signature 164 177 2.3E-36 T 28-03-2018 CIG75_RS14155 4de53accfd3d711c52a9cc61cf0dfcac 193 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 8.3E-13 T 28-03-2018 CIG75_RS14155 4de53accfd3d711c52a9cc61cf0dfcac 193 PRINTS PR00096 Glutamine amidotransferase superfamily signature 164 177 8.3E-13 T 28-03-2018 CIG75_RS14155 4de53accfd3d711c52a9cc61cf0dfcac 193 PRINTS PR00096 Glutamine amidotransferase superfamily signature 47 56 8.3E-13 T 28-03-2018 CIG75_RS14155 4de53accfd3d711c52a9cc61cf0dfcac 193 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 1 185 3.1E-81 T 28-03-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CIG75_RS14155 4de53accfd3d711c52a9cc61cf0dfcac 193 Gene3D G3DSA:3.40.50.880 1 188 1.1E-58 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CIG75_RS14155 4de53accfd3d711c52a9cc61cf0dfcac 193 SUPERFAMILY SSF52317 1 186 2.79E-57 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CIG75_RS05020 8ab7df7cbf1095618123e59da665ad97 342 Pfam PF00534 Glycosyl transferases group 1 146 304 5.5E-24 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CIG75_RS05020 8ab7df7cbf1095618123e59da665ad97 342 SUPERFAMILY SSF53756 2 330 6.28E-53 T 28-03-2018 CIG75_RS05020 8ab7df7cbf1095618123e59da665ad97 342 Gene3D G3DSA:3.40.50.2000 140 316 6.2E-40 T 28-03-2018 CIG75_RS05065 fa3ad884c534aa0ee8ccdfa12935b9e7 171 Pfam PF13785 Domain of unknown function (DUF4178) 28 160 8.0E-16 T 28-03-2018 IPR025235 Domain of unknown function DUF4178 CIG75_RS06490 ea524a10d26e301fa1080ac13e41f1d6 96 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 75 5.9E-20 T 28-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain CIG75_RS06490 ea524a10d26e301fa1080ac13e41f1d6 96 SUPERFAMILY SSF54909 1 94 8.67E-27 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CIG75_RS06490 ea524a10d26e301fa1080ac13e41f1d6 96 Gene3D G3DSA:3.30.70.100 1 93 6.6E-21 T 28-03-2018 CIG75_RS03420 2c9b04988252edaa20257ff32eb3135a 212 Pfam PF09335 SNARE associated Golgi protein 57 171 2.0E-23 T 28-03-2018 IPR032816 SNARE associated Golgi protein CIG75_RS00015 8d56819bc21088b977c25b040a50bfc8 222 Pfam PF04468 PSP1 C-terminal conserved region 61 146 1.9E-33 T 28-03-2018 IPR007557 PSP1, C-terminal CIG75_RS12870 b45f71e7c75e306908cced44ff799141 152 Gene3D G3DSA:1.10.4010.10 2 142 8.0E-4 T 28-03-2018 CIG75_RS11300 773aaf15da63bae6464da6bc6c2f046c 259 SUPERFAMILY SSF53335 12 259 6.18E-49 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CIG75_RS11300 773aaf15da63bae6464da6bc6c2f046c 259 Pfam PF08241 Methyltransferase domain 50 146 2.8E-23 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CIG75_RS11300 773aaf15da63bae6464da6bc6c2f046c 259 Gene3D G3DSA:3.40.50.150 2 259 5.7E-45 T 28-03-2018 CIG75_RS17645 a108bcc3a6259886ece3d57060253fb6 254 Pfam PF11251 Protein of unknown function (DUF3050) 18 248 2.6E-98 T 28-03-2018 IPR024423 Protein of unknown function DUF3050 CIG75_RS17645 a108bcc3a6259886ece3d57060253fb6 254 Gene3D G3DSA:1.20.910.10 3 254 1.3E-44 T 28-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CIG75_RS17645 a108bcc3a6259886ece3d57060253fb6 254 SMART SM01236 100 202 0.0044 T 28-03-2018 CIG75_RS17645 a108bcc3a6259886ece3d57060253fb6 254 SUPERFAMILY SSF48613 110 250 5.34E-12 T 28-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CIG75_RS13490 841e8f4095776124bb00f39751b86359 348 Pfam PF01098 Cell cycle protein 2 347 2.0E-119 T 28-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 CIG75_RS13490 841e8f4095776124bb00f39751b86359 348 TIGRFAM TIGR02615 spoVE: stage V sporulation protein E 1 345 6.4E-150 T 28-03-2018 IPR013438 Sporulation stage V, protein E CIG75_RS13490 841e8f4095776124bb00f39751b86359 348 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 1 346 3.4E-122 T 28-03-2018 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 CIG75_RS05460 95fed936bb22ef9c94804b0bdb501bca 229 PIRSF PIRSF032442 2 229 4.3E-54 T 28-03-2018 IPR016997 Uncharacterised conserved protein UCP032442 CIG75_RS05460 95fed936bb22ef9c94804b0bdb501bca 229 Pfam PF13529 Peptidase_C39 like family 40 200 2.6E-30 T 28-03-2018 CIG75_RS05460 95fed936bb22ef9c94804b0bdb501bca 229 Gene3D G3DSA:3.90.70.10 50 229 2.4E-21 T 28-03-2018 CIG75_RS02260 81470d863640b8e195abfcf40976be91 259 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS02260 81470d863640b8e195abfcf40976be91 259 Pfam PF00005 ABC transporter 30 184 1.1E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS02260 81470d863640b8e195abfcf40976be91 259 SUPERFAMILY SSF52540 9 246 5.2E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS02260 81470d863640b8e195abfcf40976be91 259 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 13 259 3.7E-125 T 28-03-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 CIG75_RS02260 81470d863640b8e195abfcf40976be91 259 SMART SM00382 37 238 2.4E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS02260 81470d863640b8e195abfcf40976be91 259 Gene3D G3DSA:3.40.50.300 9 256 2.3E-60 T 28-03-2018 CIG75_RS05955 16305a453a49fc843f97bb589c2989cb 258 SUPERFAMILY SSF52540 41 213 4.93E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS05955 16305a453a49fc843f97bb589c2989cb 258 Pfam PF13476 AAA domain 41 68 3.8E-7 T 28-03-2018 CIG75_RS05955 16305a453a49fc843f97bb589c2989cb 258 Gene3D G3DSA:3.40.50.300 17 226 2.7E-19 T 28-03-2018 CIG75_RS05955 16305a453a49fc843f97bb589c2989cb 258 SMART SM00382 45 230 2.9E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS05955 16305a453a49fc843f97bb589c2989cb 258 Pfam PF13175 AAA ATPase domain 158 210 9.8E-10 T 28-03-2018 CIG75_RS01375 3d3587266e7988bad891b0f053f9ca1a 115 Gene3D G3DSA:3.40.1360.20 1 114 5.1E-17 T 28-03-2018 CIG75_RS01375 3d3587266e7988bad891b0f053f9ca1a 115 SUPERFAMILY SSF110455 1 110 4.18E-29 T 28-03-2018 CIG75_RS01375 3d3587266e7988bad891b0f053f9ca1a 115 Pfam PF13155 Toprim-like 19 83 3.2E-5 T 28-03-2018 CIG75_RS01375 3d3587266e7988bad891b0f053f9ca1a 115 SMART SM00493 5 80 1.4E-7 T 28-03-2018 IPR006171 TOPRIM domain CIG75_RS18600 8dec23501325293574f16ba160a9b8e2 421 SUPERFAMILY SSF103473 12 402 9.55E-50 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS18600 8dec23501325293574f16ba160a9b8e2 421 Pfam PF05977 Transmembrane secretion effector 6 396 8.5E-44 T 28-03-2018 IPR010290 Transmembrane secretion effector CIG75_RS18600 8dec23501325293574f16ba160a9b8e2 421 Gene3D G3DSA:1.20.1250.20 1 195 4.5E-25 T 28-03-2018 CIG75_RS18600 8dec23501325293574f16ba160a9b8e2 421 Gene3D G3DSA:1.20.1250.20 208 401 1.7E-15 T 28-03-2018 CIG75_RS15830 291211e0e6408d3091cbbadb34790eee 396 Pfam PF07690 Major Facilitator Superfamily 12 341 2.7E-47 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CIG75_RS15830 291211e0e6408d3091cbbadb34790eee 396 SUPERFAMILY SSF103473 4 385 1.96E-69 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS15830 291211e0e6408d3091cbbadb34790eee 396 Gene3D G3DSA:1.20.1250.20 193 387 2.3E-21 T 28-03-2018 CIG75_RS15830 291211e0e6408d3091cbbadb34790eee 396 Gene3D G3DSA:1.20.1250.20 3 192 1.4E-37 T 28-03-2018 CIG75_RS15800 287d2d25dc65b03258f299eddcf7e688 118 SUPERFAMILY SSF46785 20 116 1.91E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS15800 287d2d25dc65b03258f299eddcf7e688 118 Gene3D G3DSA:1.10.10.10 1 118 2.0E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS15800 287d2d25dc65b03258f299eddcf7e688 118 Pfam PF01022 Bacterial regulatory protein, arsR family 42 87 5.8E-18 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CIG75_RS15800 287d2d25dc65b03258f299eddcf7e688 118 SMART SM00418 35 113 2.2E-30 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CIG75_RS15800 287d2d25dc65b03258f299eddcf7e688 118 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 58 76 - T 28-03-2018 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 CIG75_RS15800 287d2d25dc65b03258f299eddcf7e688 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 37 52 1.2E-18 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CIG75_RS15800 287d2d25dc65b03258f299eddcf7e688 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 69 84 1.2E-18 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CIG75_RS15800 287d2d25dc65b03258f299eddcf7e688 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 56 67 1.2E-18 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CIG75_RS15800 287d2d25dc65b03258f299eddcf7e688 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 84 99 1.2E-18 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CIG75_RS03600 f852282e45ae917978fd7f50b988ef8e 272 Pfam PF10978 Protein of unknown function (DUF2785) 79 246 1.3E-47 T 28-03-2018 IPR021247 Protein of unknown function DUF2785 CIG75_RS13200 4d7b9d878749802e9c1fb99a12c81fc9 253 SUPERFAMILY SSF64438 6 246 6.78E-79 T 28-03-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic CIG75_RS13200 4d7b9d878749802e9c1fb99a12c81fc9 253 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 19 246 2.1E-56 T 28-03-2018 IPR003730 Multi-copper polyphenol oxidoreductase CIG75_RS13200 4d7b9d878749802e9c1fb99a12c81fc9 253 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 17 245 1.8E-74 T 28-03-2018 IPR003730 Multi-copper polyphenol oxidoreductase CIG75_RS13200 4d7b9d878749802e9c1fb99a12c81fc9 253 Gene3D G3DSA:3.60.140.10 4 251 2.7E-79 T 28-03-2018 CIG75_RS06330 4416e2cb5eff9ed3719e9a069b7bb1d8 420 Pfam PF12791 Anti-sigma factor N-terminus 14 53 1.6E-6 T 28-03-2018 IPR024449 Anti-sigma factor RsgI, N-terminal CIG75_RS10610 be98b13f0e0f7df9c2e6a3dbadfa1ce9 410 Gene3D G3DSA:1.20.1250.20 6 202 2.7E-17 T 28-03-2018 CIG75_RS10610 be98b13f0e0f7df9c2e6a3dbadfa1ce9 410 Gene3D G3DSA:1.20.1250.20 204 397 1.5E-10 T 28-03-2018 CIG75_RS10610 be98b13f0e0f7df9c2e6a3dbadfa1ce9 410 Pfam PF07690 Major Facilitator Superfamily 22 354 4.1E-24 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CIG75_RS10610 be98b13f0e0f7df9c2e6a3dbadfa1ce9 410 SUPERFAMILY SSF103473 15 396 3.27E-36 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS19225 cf9cc57f866e5932e09a56f0c368fb6e 317 Pfam PF03837 RecT family 25 196 3.6E-29 T 28-03-2018 IPR018330 RecT family GO:0003677|GO:0006259 CIG75_RS02230 88ea39d49b493a684f0d3b133cda250d 146 Gene3D G3DSA:3.90.550.10 35 115 1.7E-5 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CIG75_RS00645 68a1675a91e2ac3ce69002c717029d53 74 SMART SM00530 6 62 1.9E-7 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS00645 68a1675a91e2ac3ce69002c717029d53 74 Gene3D G3DSA:1.10.260.40 2 72 1.8E-11 T 28-03-2018 CIG75_RS00645 68a1675a91e2ac3ce69002c717029d53 74 SUPERFAMILY SSF47413 1 66 1.13E-18 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CIG75_RS00645 68a1675a91e2ac3ce69002c717029d53 74 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 6 66 8.2E-24 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS09405 732a3e9086fce99e04c11e9f5e15b2c3 190 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 1 187 18.834 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CIG75_RS09405 732a3e9086fce99e04c11e9f5e15b2c3 190 Pfam PF02660 Glycerol-3-phosphate acyltransferase 3 178 1.5E-49 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CIG75_RS09405 732a3e9086fce99e04c11e9f5e15b2c3 190 SMART SM01207 2 179 1.8E-71 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CIG75_RS09405 732a3e9086fce99e04c11e9f5e15b2c3 190 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 1 188 3.9E-53 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CIG75_RS16415 4ba6a8f980d3a64bf5b59f68298007ed 468 SUPERFAMILY SSF103473 59 451 7.19E-44 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS16415 4ba6a8f980d3a64bf5b59f68298007ed 468 Pfam PF07690 Major Facilitator Superfamily 71 406 2.5E-29 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CIG75_RS16415 4ba6a8f980d3a64bf5b59f68298007ed 468 Gene3D G3DSA:1.20.1250.20 256 460 4.5E-21 T 28-03-2018 CIG75_RS16415 4ba6a8f980d3a64bf5b59f68298007ed 468 Gene3D G3DSA:1.20.1250.20 46 252 1.2E-22 T 28-03-2018 CIG75_RS20435 a289048505c5a0ad3830a443c7d282f5 191 TIGRFAM TIGR00334 5S_RNA_mat_M5: ribonuclease M5 2 173 1.3E-40 T 28-03-2018 IPR004466 Ribonuclease M5 GO:0043822 CIG75_RS20435 a289048505c5a0ad3830a443c7d282f5 191 Hamap MF_01469 Ribonuclease M5 [rnmV]. 2 177 28.873 T 28-03-2018 IPR004466 Ribonuclease M5 GO:0043822 CIG75_RS20435 a289048505c5a0ad3830a443c7d282f5 191 Pfam PF13331 Domain of unknown function (DUF4093) 91 174 1.0E-23 T 28-03-2018 IPR025156 Ribonuclease M5, C-terminal domain CIG75_RS20435 a289048505c5a0ad3830a443c7d282f5 191 SUPERFAMILY SSF110455 2 113 7.06E-29 T 28-03-2018 CIG75_RS20435 a289048505c5a0ad3830a443c7d282f5 191 SMART SM00493 4 77 5.1E-5 T 28-03-2018 IPR006171 TOPRIM domain CIG75_RS20435 a289048505c5a0ad3830a443c7d282f5 191 Pfam PF13662 Toprim domain 4 64 6.2E-5 T 28-03-2018 IPR006171 TOPRIM domain CIG75_RS20435 a289048505c5a0ad3830a443c7d282f5 191 Gene3D G3DSA:3.40.1360.20 1 119 1.8E-22 T 28-03-2018 CIG75_RS07655 1352b3b6ce454d5d474e3a7dbf4e1b58 458 Gene3D G3DSA:1.10.3210.10 234 448 4.6E-49 T 28-03-2018 CIG75_RS07655 1352b3b6ce454d5d474e3a7dbf4e1b58 458 SMART SM00471 269 411 4.3E-12 T 28-03-2018 IPR003607 HD/PDEase domain CIG75_RS07655 1352b3b6ce454d5d474e3a7dbf4e1b58 458 TIGRFAM TIGR00277 HDIG: HDIG domain 273 351 2.7E-7 T 28-03-2018 IPR006675 HDIG domain CIG75_RS07655 1352b3b6ce454d5d474e3a7dbf4e1b58 458 Pfam PF01966 HD domain 274 402 8.9E-23 T 28-03-2018 IPR006674 HD domain CIG75_RS07655 1352b3b6ce454d5d474e3a7dbf4e1b58 458 SUPERFAMILY SSF109604 255 441 2.9E-40 T 28-03-2018 CIG75_RS07270 7e03f29fd26cde9b2f41846215398983 538 Pfam PF09491 AlwI restriction endonuclease 82 204 1.9E-8 T 28-03-2018 IPR018573 Restriction endonuclease, type II, AlwI CIG75_RS07270 7e03f29fd26cde9b2f41846215398983 538 Gene3D G3DSA:3.40.91.30 358 517 5.2E-37 T 28-03-2018 CIG75_RS02030 9d0edee7b44f34c747c76e5f8aa2b38a 349 TIGRFAM TIGR02870 spore_II_D: stage II sporulation protein D 50 340 1.2E-104 T 28-03-2018 IPR014225 Sporulation stage II, protein D firmicutes CIG75_RS02030 9d0edee7b44f34c747c76e5f8aa2b38a 349 Pfam PF08486 Stage II sporulation protein 74 176 1.7E-21 T 28-03-2018 IPR013693 Sporulation stage II protein D, amidase enhancer LytB N-terminal CIG75_RS02030 9d0edee7b44f34c747c76e5f8aa2b38a 349 TIGRFAM TIGR02669 SpoIID_LytB: SpoIID/LytB domain 77 340 1.3E-65 T 28-03-2018 IPR013486 Sporulation stage II protein D, amidase enhancer LytB GO:0030435 CIG75_RS05960 cd529ef54d3981cfe5df702ac0d2f64d 201 Pfam PF00805 Pentapeptide repeats (8 copies) 148 184 1.6E-6 T 28-03-2018 IPR001646 Pentapeptide repeat CIG75_RS05960 cd529ef54d3981cfe5df702ac0d2f64d 201 Gene3D G3DSA:2.160.10.20 3 68 2.4E-12 T 28-03-2018 CIG75_RS05960 cd529ef54d3981cfe5df702ac0d2f64d 201 Gene3D G3DSA:2.160.10.20 129 194 3.6E-16 T 28-03-2018 CIG75_RS05960 cd529ef54d3981cfe5df702ac0d2f64d 201 Gene3D G3DSA:2.160.10.20 69 128 7.2E-14 T 28-03-2018 CIG75_RS05960 cd529ef54d3981cfe5df702ac0d2f64d 201 Pfam PF13599 Pentapeptide repeats (9 copies) 66 145 9.8E-9 T 28-03-2018 IPR001646 Pentapeptide repeat CIG75_RS05960 cd529ef54d3981cfe5df702ac0d2f64d 201 Pfam PF13599 Pentapeptide repeats (9 copies) 8 62 2.0E-8 T 28-03-2018 IPR001646 Pentapeptide repeat CIG75_RS05960 cd529ef54d3981cfe5df702ac0d2f64d 201 SUPERFAMILY SSF141571 13 185 2.68E-42 T 28-03-2018 CIG75_RS00375 73d21eac5b19015d383bb200c7b75d4f 366 SUPERFAMILY SSF58100 21 355 1.52E-35 T 28-03-2018 CIG75_RS00375 73d21eac5b19015d383bb200c7b75d4f 366 Gene3D G3DSA:1.20.1170.10 3 354 2.5E-29 T 28-03-2018 CIG75_RS00375 73d21eac5b19015d383bb200c7b75d4f 366 Pfam PF05791 Bacillus haemolytic enterotoxin (HBL) 30 192 1.5E-10 T 28-03-2018 IPR008414 Hemolysin BL-binding component GO:0009405|GO:0016020 CIG75_RS12315 04092d03e6b4c7a3fca9b756f84733ce 90 Gene3D G3DSA:3.30.1320.10 2 85 1.8E-35 T 28-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS12315 04092d03e6b4c7a3fca9b756f84733ce 90 SUPERFAMILY SSF54565 2 85 1.57E-35 T 28-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS12315 04092d03e6b4c7a3fca9b756f84733ce 90 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 2 77 25.897 T 28-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS12315 04092d03e6b4c7a3fca9b756f84733ce 90 TIGRFAM TIGR00002 S16: ribosomal protein bS16 3 79 2.0E-36 T 28-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS12315 04092d03e6b4c7a3fca9b756f84733ce 90 Pfam PF00886 Ribosomal protein S16 9 67 1.3E-26 T 28-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CIG75_RS17200 1573f1cf221f3c45d9cf659af35dd906 321 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 8 124 7.5E-46 T 28-03-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CIG75_RS17200 1573f1cf221f3c45d9cf659af35dd906 321 Gene3D G3DSA:3.40.50.2020 5 158 1.1E-64 T 28-03-2018 CIG75_RS17200 1573f1cf221f3c45d9cf659af35dd906 321 SUPERFAMILY SSF53271 6 161 7.42E-51 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CIG75_RS17200 1573f1cf221f3c45d9cf659af35dd906 321 Gene3D G3DSA:3.40.50.2020 159 292 4.5E-31 T 28-03-2018 CIG75_RS17200 1573f1cf221f3c45d9cf659af35dd906 321 SUPERFAMILY SSF53271 110 307 1.7E-43 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CIG75_RS17200 1573f1cf221f3c45d9cf659af35dd906 321 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 8 316 43.03 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CIG75_RS17200 1573f1cf221f3c45d9cf659af35dd906 321 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 9 314 3.0E-110 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CIG75_RS17200 1573f1cf221f3c45d9cf659af35dd906 321 Pfam PF14572 Phosphoribosyl synthetase-associated domain 207 314 4.4E-19 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CIG75_RS17200 1573f1cf221f3c45d9cf659af35dd906 321 SMART SM01400 8 124 2.6E-69 T 28-03-2018 CIG75_RS00555 6384c5881255bf36ead34fc126d92a4e 266 Pfam PF12706 Beta-lactamase superfamily domain 22 206 4.3E-23 T 28-03-2018 IPR001279 Metallo-beta-lactamase CIG75_RS00555 6384c5881255bf36ead34fc126d92a4e 266 SMART SM00849 11 217 3.8E-12 T 28-03-2018 IPR001279 Metallo-beta-lactamase CIG75_RS00555 6384c5881255bf36ead34fc126d92a4e 266 Gene3D G3DSA:3.60.15.10 8 262 6.2E-39 T 28-03-2018 IPR001279 Metallo-beta-lactamase CIG75_RS00555 6384c5881255bf36ead34fc126d92a4e 266 SUPERFAMILY SSF56281 6 224 6.81E-43 T 28-03-2018 IPR001279 Metallo-beta-lactamase CIG75_RS06545 a2860df0e86b598c15725e5f9fc203be 365 Gene3D G3DSA:3.90.70.10 43 242 6.7E-21 T 28-03-2018 CIG75_RS06545 a2860df0e86b598c15725e5f9fc203be 365 Pfam PF13529 Peptidase_C39 like family 35 196 1.0E-31 T 28-03-2018 CIG75_RS05430 8eb98c80fe7eaa163177d75523bb70cf 271 Pfam PF03787 RAMP superfamily 18 228 4.9E-25 T 28-03-2018 IPR005537 CRISPR type III-associated RAMP protein CIG75_RS05430 8eb98c80fe7eaa163177d75523bb70cf 271 TIGRFAM TIGR02581 cas_cyan_RAMP: CRISPR-associated RAMP protein, SSO1426 family 9 227 1.3E-44 T 28-03-2018 IPR013411 CRISPR-associated RAMP TM1809 CIG75_RS11850 6da87ce84b5b78babb28940af8e6f1de 282 SUPERFAMILY SSF51695 46 281 1.99E-78 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CIG75_RS11850 6da87ce84b5b78babb28940af8e6f1de 282 Gene3D G3DSA:3.20.20.190 19 282 6.1E-79 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CIG75_RS11850 6da87ce84b5b78babb28940af8e6f1de 282 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 51 278 6.9E-53 T 28-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 CIG75_RS01725 8b744c845711fa5bd8e0ed240c814d7a 131 SUPERFAMILY SSF54637 6 127 3.25E-16 T 28-03-2018 IPR029069 HotDog domain CIG75_RS01725 8b744c845711fa5bd8e0ed240c814d7a 131 Gene3D G3DSA:3.10.129.10 1 129 1.5E-19 T 28-03-2018 CIG75_RS01725 8b744c845711fa5bd8e0ed240c814d7a 131 Pfam PF03061 Thioesterase superfamily 25 90 1.8E-5 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CIG75_RS07555 07a85e32f5328e9d595e2f6b233701e8 182 Pfam PF04367 Protein of unknown function (DUF502) 47 149 3.7E-27 T 28-03-2018 IPR007462 Protein of unknown function DUF502 CIG75_RS08855 84d41484bc2c335fd8aa1f4ccd0bcd7b 395 Pfam PF01578 Cytochrome C assembly protein 73 197 3.0E-9 T 28-03-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 CIG75_RS08855 84d41484bc2c335fd8aa1f4ccd0bcd7b 395 Pfam PF01578 Cytochrome C assembly protein 295 392 2.1E-29 T 28-03-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 CIG75_RS08855 84d41484bc2c335fd8aa1f4ccd0bcd7b 395 TIGRFAM TIGR03144 cytochr_II_ccsB: cytochrome c-type biogenesis protein CcsB 49 395 1.5E-73 T 28-03-2018 IPR017562 Cytochrome c-type biogenesis protein CcsA GO:0017004 CIG75_RS04080 e607ebf535de10885ca8130e7dd438a0 175 Gene3D G3DSA:3.40.630.30 6 175 8.9E-30 T 28-03-2018 CIG75_RS04080 e607ebf535de10885ca8130e7dd438a0 175 Pfam PF00583 Acetyltransferase (GNAT) family 49 148 1.5E-16 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CIG75_RS04080 e607ebf535de10885ca8130e7dd438a0 175 SUPERFAMILY SSF55729 4 172 1.89E-32 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CIG75_RS00050 84ba551ce4c988be8f7ca5d13529ddc5 75 Pfam PF10764 Inhibitor of sigma-G Gin 23 67 1.4E-18 T 28-03-2018 IPR019700 Anti-sigma-G factor Gin CIG75_RS09950 a6a050f9c60389e4d28a39af92edbe8b 263 Hamap MF_01963 S-methyl-5'-thioadenosine phosphorylase [mtnP]. 3 262 40.084 T 28-03-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112 CIG75_RS09950 a6a050f9c60389e4d28a39af92edbe8b 263 Gene3D G3DSA:3.40.50.1580 2 244 3.0E-53 T 28-03-2018 CIG75_RS09950 a6a050f9c60389e4d28a39af92edbe8b 263 Pfam PF01048 Phosphorylase superfamily 5 240 1.3E-48 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CIG75_RS09950 a6a050f9c60389e4d28a39af92edbe8b 263 SUPERFAMILY SSF53167 4 258 8.76E-90 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CIG75_RS09950 a6a050f9c60389e4d28a39af92edbe8b 263 TIGRFAM TIGR01694 MTAP: methylthioadenosine phosphorylase 5 243 2.0E-92 T 28-03-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112 CIG75_RS06285 9a0ec910e732e00b0b530198212647f5 414 Gene3D G3DSA:1.20.1250.20 208 412 5.4E-24 T 28-03-2018 CIG75_RS06285 9a0ec910e732e00b0b530198212647f5 414 ProSitePatterns PS00216 Sugar transport proteins signature 1. 69 85 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CIG75_RS06285 9a0ec910e732e00b0b530198212647f5 414 Gene3D G3DSA:1.20.1250.20 10 205 5.0E-32 T 28-03-2018 CIG75_RS06285 9a0ec910e732e00b0b530198212647f5 414 Pfam PF07690 Major Facilitator Superfamily 20 300 7.9E-35 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CIG75_RS06285 9a0ec910e732e00b0b530198212647f5 414 SUPERFAMILY SSF103473 14 404 3.14E-63 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS10885 fb289268c4e6264ca31cdb2bdc9eef73 278 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 8 243 3.5E-81 T 28-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CIG75_RS10885 fb289268c4e6264ca31cdb2bdc9eef73 278 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 14 270 34.712 T 28-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CIG75_RS10885 fb289268c4e6264ca31cdb2bdc9eef73 278 Gene3D G3DSA:3.20.20.70 2 276 5.9E-76 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CIG75_RS10885 fb289268c4e6264ca31cdb2bdc9eef73 278 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 48 61 - T 28-03-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CIG75_RS10885 fb289268c4e6264ca31cdb2bdc9eef73 278 Pfam PF00290 Tryptophan synthase alpha chain 8 248 2.1E-85 T 28-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CIG75_RS10885 fb289268c4e6264ca31cdb2bdc9eef73 278 SUPERFAMILY SSF51366 1 238 8.57E-82 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CIG75_RS11100 b44262f0c3337315fc71566d7eda7f21 294 Pfam PF12679 ABC-2 family transporter protein 15 270 4.1E-8 T 28-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 CIG75_RS11425 ba48f0e0bc9a9124cccd8b020dfc1d4a 237 SUPERFAMILY SSF102215 2 233 1.83E-51 T 28-03-2018 IPR024087 Creatininase-like domain KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 CIG75_RS11425 ba48f0e0bc9a9124cccd8b020dfc1d4a 237 Pfam PF02633 Creatinine amidohydrolase 7 227 2.0E-50 T 28-03-2018 IPR003785 Creatininase/formamide hydrolase KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 CIG75_RS11425 ba48f0e0bc9a9124cccd8b020dfc1d4a 237 Gene3D G3DSA:3.40.50.10310 1 236 1.6E-57 T 28-03-2018 IPR024087 Creatininase-like domain KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 CIG75_RS09390 5033ab0469ec9bb44acdcd4218085a16 149 Pfam PF11385 Protein of unknown function (DUF3189) 5 97 2.0E-9 T 28-03-2018 IPR021525 Protein of unknown function DUF3189 CIG75_RS02170 0316d31863b4e3d497dcf90d8b73a386 65 SUPERFAMILY SSF140500 4 54 1.05E-9 T 28-03-2018 CIG75_RS02170 0316d31863b4e3d497dcf90d8b73a386 65 Pfam PF09388 Spo0E like sporulation regulatory protein 7 49 5.9E-14 T 28-03-2018 IPR018540 Aspartyl-phosphate phosphatase Spo0E-like GO:0043937 CIG75_RS00650 efc76fb20bd8db25e065c385d86b434e 217 Gene3D G3DSA:3.40.50.360 2 215 2.8E-30 T 28-03-2018 IPR029039 Flavoprotein-like domain CIG75_RS00650 efc76fb20bd8db25e065c385d86b434e 217 Pfam PF02525 Flavodoxin-like fold 2 204 1.2E-39 T 28-03-2018 IPR003680 Flavodoxin-like fold CIG75_RS00650 efc76fb20bd8db25e065c385d86b434e 217 SUPERFAMILY SSF52218 1 209 1.28E-42 T 28-03-2018 IPR029039 Flavoprotein-like domain CIG75_RS00650 efc76fb20bd8db25e065c385d86b434e 217 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 2 210 25.993 T 28-03-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 CIG75_RS03950 fc2fef60450b248432643b3fb425a9fb 202 Pfam PF09998 Uncharacterized protein conserved in bacteria (DUF2239) 10 194 4.9E-71 T 28-03-2018 IPR018715 Protein of unknown function DUF2239 CIG75_RS08220 0b531d3696c73775cbeb52c77bbdf42f 158 Pfam PF13291 ACT domain 81 152 1.0E-6 T 28-03-2018 IPR002912 ACT domain CIG75_RS08220 0b531d3696c73775cbeb52c77bbdf42f 158 Hamap MF_00707 UPF0735 ACT domain-containing protein . 14 158 29.852 T 28-03-2018 IPR008310 UPF0735 ACT domain-containing protein CIG75_RS08220 0b531d3696c73775cbeb52c77bbdf42f 158 Gene3D G3DSA:3.30.70.260 79 158 3.5E-11 T 28-03-2018 CIG75_RS08220 0b531d3696c73775cbeb52c77bbdf42f 158 SUPERFAMILY SSF55021 82 154 1.86E-10 T 28-03-2018 CIG75_RS08220 0b531d3696c73775cbeb52c77bbdf42f 158 PIRSF PIRSF025624 10 158 4.7E-48 T 28-03-2018 IPR008310 UPF0735 ACT domain-containing protein CIG75_RS20200 1ffc24af34516d9c96175e599041bcb8 181 Hamap MF_00357 Probable DNA-directed RNA polymerase subunit delta [rpoE]. 11 179 13.048 T 28-03-2018 IPR029757 DNA-directed RNA polymerase subunit delta GO:0006351|GO:0006355 CIG75_RS20200 1ffc24af34516d9c96175e599041bcb8 181 TIGRFAM TIGR04567 RNAP_delt_lowGC: DNA-directed RNA polymerase delta subunit 15 90 1.5E-31 T 28-03-2018 IPR029757 DNA-directed RNA polymerase subunit delta GO:0006351|GO:0006355 CIG75_RS20200 1ffc24af34516d9c96175e599041bcb8 181 Pfam PF05066 HB1, ASXL, restriction endonuclease HTH domain 17 83 3.2E-10 T 28-03-2018 IPR007759 HB1/Asxl, restriction endonuclease HTH domain GO:0006351|GO:0006355 CIG75_RS04435 58103a2112f7bdfd8611435dd757e1cb 931 Pfam PF02687 FtsX-like permease family 325 424 2.2E-7 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CIG75_RS04435 58103a2112f7bdfd8611435dd757e1cb 931 Pfam PF02687 FtsX-like permease family 830 922 3.4E-10 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CIG75_RS04435 58103a2112f7bdfd8611435dd757e1cb 931 Pfam PF12704 MacB-like periplasmic core domain 43 221 2.2E-10 T 28-03-2018 IPR025857 MacB-like periplasmic core domain CIG75_RS06270 66368243428bd431e619f458f33627f4 335 Pfam PF13349 Putative adhesin 29 330 5.6E-17 T 28-03-2018 IPR025164 Putative adhesin CIG75_RS14950 b00b9ddf491c45750d6a977156d48204 156 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 153 78.303 T 28-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 CIG75_RS14950 b00b9ddf491c45750d6a977156d48204 156 Pfam PF03477 ATP cone domain 50 136 2.5E-19 T 28-03-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 CIG75_RS14950 b00b9ddf491c45750d6a977156d48204 156 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 144 1.1E-55 T 28-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 CIG75_RS14145 66e48596b6f78705681012171dcea607 150 SUPERFAMILY SSF141523 23 149 1.15E-31 T 28-03-2018 CIG75_RS14145 66e48596b6f78705681012171dcea607 150 Pfam PF03734 L,D-transpeptidase catalytic domain 25 148 5.3E-22 T 28-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 CIG75_RS14145 66e48596b6f78705681012171dcea607 150 Gene3D G3DSA:2.40.440.10 18 150 3.8E-32 T 28-03-2018 CIG75_RS12470 d6ec074f98e152f5214707c82e377b0e 36 Pfam PF08183 Stage V sporulation protein family 11 33 5.7E-15 T 28-03-2018 IPR012609 Sporulation stage V, protein M CIG75_RS01475 4234932762a924e3d64bc9ff167aed53 258 Pfam PF01925 Sulfite exporter TauE/SafE 9 252 1.4E-42 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 CIG75_RS07500 593fa226660a40c795c99dddc6fc9487 293 SUPERFAMILY SSF55729 3 132 2.4E-18 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CIG75_RS07500 593fa226660a40c795c99dddc6fc9487 293 Pfam PF00583 Acetyltransferase (GNAT) family 22 116 4.6E-9 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CIG75_RS07500 593fa226660a40c795c99dddc6fc9487 293 Gene3D G3DSA:3.40.630.30 135 268 0.0022 T 28-03-2018 CIG75_RS07500 593fa226660a40c795c99dddc6fc9487 293 Gene3D G3DSA:3.40.630.30 2 134 5.9E-20 T 28-03-2018 CIG75_RS07575 606bab3a2b57ee323ed36bc08d67526b 297 Pfam PF00892 EamA-like transporter family 147 278 3.2E-21 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CIG75_RS07575 606bab3a2b57ee323ed36bc08d67526b 297 Pfam PF00892 EamA-like transporter family 1 134 9.3E-18 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CIG75_RS07575 606bab3a2b57ee323ed36bc08d67526b 297 SUPERFAMILY SSF103481 39 135 9.68E-10 T 28-03-2018 CIG75_RS07575 606bab3a2b57ee323ed36bc08d67526b 297 SUPERFAMILY SSF103481 180 281 1.57E-14 T 28-03-2018 CIG75_RS16550 71cc39a6f1695db37ba0595c24d6063c 149 Gene3D G3DSA:2.60.40.420 15 149 1.1E-12 T 28-03-2018 IPR008972 Cupredoxin CIG75_RS16550 71cc39a6f1695db37ba0595c24d6063c 149 Pfam PF13473 Cupredoxin-like domain 53 135 3.5E-10 T 28-03-2018 IPR028096 EfeO-type cupredoxin-like domain CIG75_RS16550 71cc39a6f1695db37ba0595c24d6063c 149 SUPERFAMILY SSF49503 65 147 9.16E-15 T 28-03-2018 IPR008972 Cupredoxin CIG75_RS16830 d468cabb4cd8cec1dfb7ad18fb64606e 316 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS16830 d468cabb4cd8cec1dfb7ad18fb64606e 316 Pfam PF00005 ABC transporter 21 158 8.8E-24 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS16830 d468cabb4cd8cec1dfb7ad18fb64606e 316 Gene3D G3DSA:3.40.50.300 1 259 2.5E-51 T 28-03-2018 CIG75_RS16830 d468cabb4cd8cec1dfb7ad18fb64606e 316 SMART SM00382 28 232 2.8E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS16830 d468cabb4cd8cec1dfb7ad18fb64606e 316 SUPERFAMILY SSF52540 2 218 2.3E-49 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS17650 1060f1030c0c1ce77c4929542509c4bd 739 Gene3D G3DSA:3.40.720.10 32 277 0.27 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CIG75_RS17650 1060f1030c0c1ce77c4929542509c4bd 739 Gene3D G3DSA:3.40.720.10 289 377 3.2E-6 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CIG75_RS17650 1060f1030c0c1ce77c4929542509c4bd 739 SUPERFAMILY SSF53649 151 352 3.92E-11 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CIG75_RS17650 1060f1030c0c1ce77c4929542509c4bd 739 SUPERFAMILY SSF53649 37 93 3.92E-11 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CIG75_RS09185 f3cf4f583512fc4549e630ee3ed0a592 407 Pfam PF02073 Thermophilic metalloprotease (M29) 4 406 3.4E-156 T 28-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CIG75_RS09185 f3cf4f583512fc4549e630ee3ed0a592 407 SUPERFAMILY SSF144052 1 407 4.84E-132 T 28-03-2018 CIG75_RS09185 f3cf4f583512fc4549e630ee3ed0a592 407 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 78 97 3.1E-59 T 28-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CIG75_RS09185 f3cf4f583512fc4549e630ee3ed0a592 407 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 299 319 3.1E-59 T 28-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CIG75_RS09185 f3cf4f583512fc4549e630ee3ed0a592 407 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 13 30 3.1E-59 T 28-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CIG75_RS09185 f3cf4f583512fc4549e630ee3ed0a592 407 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 322 343 3.1E-59 T 28-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CIG75_RS09185 f3cf4f583512fc4549e630ee3ed0a592 407 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 361 383 3.1E-59 T 28-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CIG75_RS09185 f3cf4f583512fc4549e630ee3ed0a592 407 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 387 406 3.1E-59 T 28-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CIG75_RS09185 f3cf4f583512fc4549e630ee3ed0a592 407 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 154 176 3.1E-59 T 28-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CIG75_RS09185 f3cf4f583512fc4549e630ee3ed0a592 407 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 243 262 3.1E-59 T 28-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CIG75_RS09185 f3cf4f583512fc4549e630ee3ed0a592 407 Gene3D G3DSA:3.40.1830.10 3 172 8.9E-52 T 28-03-2018 IPR035097 Peptidase M29, N-terminal CIG75_RS02335 130c3acf181797fcd134c28471597460 140 TIGRFAM TIGR03826 YvyF: flagellar operon protein TIGR03826 10 136 1.8E-38 T 28-03-2018 IPR022258 Flagellar operon protein YvyF CIG75_RS12240 5b49b2ad235b9435ed1895a82457bd12 118 Gene3D G3DSA:2.40.440.10 2 117 8.3E-33 T 28-03-2018 CIG75_RS12240 5b49b2ad235b9435ed1895a82457bd12 118 SUPERFAMILY SSF141523 4 117 4.97E-33 T 28-03-2018 CIG75_RS12240 5b49b2ad235b9435ed1895a82457bd12 118 Pfam PF03734 L,D-transpeptidase catalytic domain 5 116 5.6E-21 T 28-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 CIG75_RS13680 8e33119ca2c0f91c10377b9caea0cb2f 276 ProSitePatterns PS01065 Electron transfer flavoprotein beta-subunit signature. 164 184 - T 28-03-2018 IPR000049 Electron transfer flavoprotein, beta-subunit, conserved site GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 CIG75_RS13680 8e33119ca2c0f91c10377b9caea0cb2f 276 Pfam PF01012 Electron transfer flavoprotein domain 24 209 2.9E-41 T 28-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CIG75_RS13680 8e33119ca2c0f91c10377b9caea0cb2f 276 SMART SM00893 23 220 5.8E-50 T 28-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CIG75_RS13680 8e33119ca2c0f91c10377b9caea0cb2f 276 Gene3D G3DSA:3.40.50.620 2 270 1.2E-63 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CIG75_RS13680 8e33119ca2c0f91c10377b9caea0cb2f 276 PIRSF PIRSF000090 2 270 4.0E-77 T 28-03-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 CIG75_RS13680 8e33119ca2c0f91c10377b9caea0cb2f 276 SUPERFAMILY SSF52402 2 257 2.58E-67 T 28-03-2018 CIG75_RS05040 29dacf985dc26115fa0f66eb86190ccd 624 Pfam PF13424 Tetratricopeptide repeat 485 549 1.2E-7 T 28-03-2018 CIG75_RS05040 29dacf985dc26115fa0f66eb86190ccd 624 SMART SM00028 557 590 66.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS05040 29dacf985dc26115fa0f66eb86190ccd 624 SMART SM00028 336 370 180.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS05040 29dacf985dc26115fa0f66eb86190ccd 624 SMART SM00028 517 551 8.9 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS05040 29dacf985dc26115fa0f66eb86190ccd 624 Gene3D G3DSA:1.25.40.10 477 536 2.2E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS05040 29dacf985dc26115fa0f66eb86190ccd 624 SUPERFAMILY SSF48452 300 464 9.34E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS05040 29dacf985dc26115fa0f66eb86190ccd 624 Gene3D G3DSA:1.25.40.10 537 591 1.9E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS05040 29dacf985dc26115fa0f66eb86190ccd 624 SUPERFAMILY SSF48452 438 589 8.22E-16 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS05040 29dacf985dc26115fa0f66eb86190ccd 624 Gene3D G3DSA:1.25.40.10 249 475 2.8E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS01365 9f953809fad9de3e9d0caa9ce7b3efac 268 SUPERFAMILY SSF47781 180 261 7.11E-11 T 28-03-2018 IPR010994 RuvA domain 2-like CIG75_RS01365 9f953809fad9de3e9d0caa9ce7b3efac 268 Pfam PF12836 Helix-hairpin-helix motif 200 259 2.3E-9 T 28-03-2018 CIG75_RS01365 9f953809fad9de3e9d0caa9ce7b3efac 268 Gene3D G3DSA:1.10.150.320 180 268 2.2E-9 T 28-03-2018 CIG75_RS04885 a5b644ea3dc971385e5b7c6cd7a1e472 167 Gene3D G3DSA:1.10.4010.10 6 167 9.7E-42 T 28-03-2018 CIG75_RS04885 a5b644ea3dc971385e5b7c6cd7a1e472 167 PIRSF PIRSF030140 7 167 1.5E-48 T 28-03-2018 IPR016947 Uncharacterised phage-associated protein UCP030140 CIG75_RS04885 a5b644ea3dc971385e5b7c6cd7a1e472 167 Pfam PF08761 dUTPase 8 167 2.3E-44 T 28-03-2018 IPR014871 dUTPase/dCTP pyrophosphatase KEGG: 00240+3.6.1.12 CIG75_RS04885 a5b644ea3dc971385e5b7c6cd7a1e472 167 SUPERFAMILY SSF101386 9 167 1.48E-38 T 28-03-2018 CIG75_RS14005 e8b1b8e5eabcaed4cd8cad318389e153 129 SUPERFAMILY SSF55811 2 126 5.28E-34 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CIG75_RS14005 e8b1b8e5eabcaed4cd8cad318389e153 129 ProSitePatterns PS00893 Nudix box signature. 37 58 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CIG75_RS14005 e8b1b8e5eabcaed4cd8cad318389e153 129 Gene3D G3DSA:3.90.79.10 2 129 1.6E-28 T 28-03-2018 CIG75_RS14005 e8b1b8e5eabcaed4cd8cad318389e153 129 PRINTS PR00502 NUDIX hydrolase family signature 32 46 4.8E-6 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CIG75_RS14005 e8b1b8e5eabcaed4cd8cad318389e153 129 PRINTS PR00502 NUDIX hydrolase family signature 46 61 4.8E-6 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CIG75_RS14005 e8b1b8e5eabcaed4cd8cad318389e153 129 Pfam PF00293 NUDIX domain 3 124 5.0E-20 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CIG75_RS18055 4d0518a380ce8568a9b958c24aefb835 242 SUPERFAMILY SSF53335 8 241 2.18E-37 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CIG75_RS18055 4d0518a380ce8568a9b958c24aefb835 242 Pfam PF08241 Methyltransferase domain 50 144 7.5E-20 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CIG75_RS18055 4d0518a380ce8568a9b958c24aefb835 242 Gene3D G3DSA:3.40.50.150 33 241 1.3E-36 T 28-03-2018 CIG75_RS20170 746d14355193c75cb3a3d78c4982b65a 365 Gene3D G3DSA:2.60.40.10 58 186 0.0011 T 28-03-2018 IPR013783 Immunoglobulin-like fold CIG75_RS05800 6a1fd11e78c409f3a2c7f17502942a20 260 Gene3D G3DSA:1.10.12.10 221 255 1.7E-8 T 28-03-2018 IPR014748 Crontonase, C-terminal CIG75_RS05800 6a1fd11e78c409f3a2c7f17502942a20 260 Pfam PF00378 Enoyl-CoA hydratase/isomerase 15 255 2.5E-52 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CIG75_RS05800 6a1fd11e78c409f3a2c7f17502942a20 260 Gene3D G3DSA:3.90.226.10 6 220 1.6E-68 T 28-03-2018 CIG75_RS05800 6a1fd11e78c409f3a2c7f17502942a20 260 SUPERFAMILY SSF52096 4 256 2.18E-73 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CIG75_RS10995 7e2f296fe75436d39372827ae61a4137 621 Gene3D G3DSA:3.40.50.720 172 316 1.7E-5 T 28-03-2018 CIG75_RS16455 8c0875b854b9a3f6ee2c3dba72cd1baf 73 Pfam PF10676 Spore germination protein gerPA/gerPF 1 69 5.4E-20 T 28-03-2018 IPR019618 Spore germination protein GerPA/GerPF CIG75_RS07250 6053346a8bf6885d84f39248061eb8ec 220 Gene3D G3DSA:3.40.50.720 1 217 1.7E-19 T 28-03-2018 CIG75_RS07250 6053346a8bf6885d84f39248061eb8ec 220 SUPERFAMILY SSF51735 1 202 2.0E-39 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS07250 6053346a8bf6885d84f39248061eb8ec 220 Pfam PF13460 NAD(P)H-binding 10 124 2.4E-9 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS02490 e274c4eb36fe182aa9ee5df89410d253 390 Gene3D G3DSA:3.40.50.620 180 381 2.8E-86 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CIG75_RS02490 e274c4eb36fe182aa9ee5df89410d253 390 SUPERFAMILY SSF88697 4 167 1.09E-49 T 28-03-2018 IPR015947 PUA-like domain CIG75_RS02490 e274c4eb36fe182aa9ee5df89410d253 390 Pfam PF14306 PUA-like domain 5 162 9.5E-53 T 28-03-2018 IPR025980 ATP-sulfurylase PUA-like domain KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 CIG75_RS02490 e274c4eb36fe182aa9ee5df89410d253 390 Gene3D G3DSA:3.10.400.10 4 179 6.3E-63 T 28-03-2018 CIG75_RS02490 e274c4eb36fe182aa9ee5df89410d253 390 Hamap MF_00066 Sulfate adenylyltransferase [sat]. 28 385 49.479 T 28-03-2018 IPR020792 Sulphate adenylyltransferase, prokaryotic-type GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 CIG75_RS02490 e274c4eb36fe182aa9ee5df89410d253 390 SUPERFAMILY SSF52374 171 381 1.09E-81 T 28-03-2018 CIG75_RS02490 e274c4eb36fe182aa9ee5df89410d253 390 TIGRFAM TIGR00339 sopT: sulfate adenylyltransferase 7 380 1.6E-134 T 28-03-2018 IPR002650 Sulphate adenylyltransferase GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 CIG75_RS02490 e274c4eb36fe182aa9ee5df89410d253 390 Pfam PF01747 ATP-sulfurylase 171 381 2.6E-90 T 28-03-2018 IPR024951 Sulphate adenylyltransferase catalytic domain GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 CIG75_RS14960 30bdac25ff31c13caad2828a852aff52 186 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 9 182 1.0E-30 T 28-03-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 CIG75_RS14960 30bdac25ff31c13caad2828a852aff52 186 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 4 180 1.8E-55 T 28-03-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 CIG75_RS14960 30bdac25ff31c13caad2828a852aff52 186 Pfam PF01923 Cobalamin adenosyltransferase 3 171 2.0E-56 T 28-03-2018 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 CIG75_RS14960 30bdac25ff31c13caad2828a852aff52 186 Gene3D G3DSA:1.20.1200.10 12 184 1.3E-55 T 28-03-2018 CIG75_RS14960 30bdac25ff31c13caad2828a852aff52 186 SUPERFAMILY SSF89028 1 181 7.06E-59 T 28-03-2018 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 CIG75_RS18520 3ef14a0b90097afd97ea56289bf62b2c 424 Pfam PF01943 Polysaccharide biosynthesis protein 6 269 4.6E-13 T 28-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 CIG75_RS20475 018e3bd73bdab8546866975310a98931 165 Gene3D G3DSA:1.25.40.10 66 156 1.7E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS20475 018e3bd73bdab8546866975310a98931 165 SMART SM00028 37 70 29.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS20475 018e3bd73bdab8546866975310a98931 165 SMART SM00028 74 107 0.09 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CIG75_RS20475 018e3bd73bdab8546866975310a98931 165 Gene3D G3DSA:1.25.40.10 1 65 1.5E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS20475 018e3bd73bdab8546866975310a98931 165 SUPERFAMILY SSF48452 7 144 7.59E-18 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS20475 018e3bd73bdab8546866975310a98931 165 Pfam PF12688 Tetratrico peptide repeat 42 155 9.2E-18 T 28-03-2018 CIG75_RS09285 e0a50893395a41657378473b954fe6fe 266 SUPERFAMILY SSF102110 17 263 1.31E-75 T 28-03-2018 IPR003830 (2R)-phospho-3-sulpholactate synthase, ComA KEGG: 00680+4.4.1.19 CIG75_RS09285 e0a50893395a41657378473b954fe6fe 266 Gene3D G3DSA:3.20.20.70 19 263 1.1E-74 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CIG75_RS09285 e0a50893395a41657378473b954fe6fe 266 Pfam PF02679 (2R)-phospho-3-sulfolactate synthase (ComA) 20 260 8.8E-80 T 28-03-2018 IPR003830 (2R)-phospho-3-sulpholactate synthase, ComA KEGG: 00680+4.4.1.19 CIG75_RS01515 0c8e345b359d16f8cd30af2f4a8c037f 98 Gene3D G3DSA:1.10.390.10 21 69 1.5E-8 T 28-03-2018 CIG75_RS10275 f8e30dd132fa53ce204c3350ede2426f 171 Pfam PF04306 Protein of unknown function (DUF456) 25 169 1.7E-27 T 28-03-2018 IPR007403 Protein of unknown function DUF456 CIG75_RS14945 93bd503cf460bca079d8938451501e8a 1062 PRINTS PR01183 Ribonucleotide reductase large chain signature 629 651 2.8E-19 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CIG75_RS14945 93bd503cf460bca079d8938451501e8a 1062 PRINTS PR01183 Ribonucleotide reductase large chain signature 399 418 2.8E-19 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CIG75_RS14945 93bd503cf460bca079d8938451501e8a 1062 PRINTS PR01183 Ribonucleotide reductase large chain signature 591 614 2.8E-19 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CIG75_RS14945 93bd503cf460bca079d8938451501e8a 1062 PRINTS PR01183 Ribonucleotide reductase large chain signature 715 742 2.8E-19 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CIG75_RS14945 93bd503cf460bca079d8938451501e8a 1062 TIGRFAM TIGR02504 NrdJ_Z: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent 312 850 3.8E-136 T 28-03-2018 IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent GO:0000166|GO:0004748|GO:0031419|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CIG75_RS14945 93bd503cf460bca079d8938451501e8a 1062 Pfam PF02867 Ribonucleotide reductase, barrel domain 377 840 1.1E-108 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CIG75_RS14945 93bd503cf460bca079d8938451501e8a 1062 Pfam PF02867 Ribonucleotide reductase, barrel domain 201 296 1.1E-5 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CIG75_RS14945 93bd503cf460bca079d8938451501e8a 1062 SUPERFAMILY SSF51998 591 852 4.88E-121 T 28-03-2018 CIG75_RS14945 93bd503cf460bca079d8938451501e8a 1062 SUPERFAMILY SSF51998 311 549 4.88E-121 T 28-03-2018 CIG75_RS14945 93bd503cf460bca079d8938451501e8a 1062 Gene3D G3DSA:3.20.70.20 198 299 1.4E-6 T 28-03-2018 CIG75_RS14945 93bd503cf460bca079d8938451501e8a 1062 Gene3D G3DSA:3.20.70.20 306 847 1.4E-127 T 28-03-2018 CIG75_RS14945 93bd503cf460bca079d8938451501e8a 1062 Gene3D G3DSA:3.20.70.20 8 197 3.9E-21 T 28-03-2018 CIG75_RS14945 93bd503cf460bca079d8938451501e8a 1062 SUPERFAMILY SSF51998 151 296 4.58E-14 T 28-03-2018 CIG75_RS12700 897e6feb077a64c7c107b70ef8922517 165 SUPERFAMILY SSF54001 3 146 8.5E-19 T 28-03-2018 CIG75_RS12700 897e6feb077a64c7c107b70ef8922517 165 Gene3D G3DSA:3.90.1720.10 1 155 3.3E-22 T 28-03-2018 CIG75_RS14485 fd7b66ae2f59d5a8f8d5ed7702401055 272 SUPERFAMILY SSF56752 2 270 4.71E-79 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CIG75_RS14485 fd7b66ae2f59d5a8f8d5ed7702401055 272 Gene3D G3DSA:3.20.10.10 122 272 2.5E-42 T 28-03-2018 CIG75_RS14485 fd7b66ae2f59d5a8f8d5ed7702401055 272 ProSitePatterns PS00770 Aminotransferases class-IV signature. 177 206 - T 28-03-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 CIG75_RS14485 fd7b66ae2f59d5a8f8d5ed7702401055 272 Pfam PF01063 Amino-transferase class IV 29 245 8.5E-55 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CIG75_RS14485 fd7b66ae2f59d5a8f8d5ed7702401055 272 Gene3D G3DSA:3.30.470.10 1 117 5.6E-37 T 28-03-2018 CIG75_RS12710 35faf52d03158b90cd1635712fb48446 588 SUPERFAMILY SSF63829 380 537 1.11E-6 T 28-03-2018 CIG75_RS12710 35faf52d03158b90cd1635712fb48446 588 Gene3D G3DSA:2.120.10.30 312 543 2.3E-7 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CIG75_RS05290 2b3b7fe6c90fde45be78094f07666bf2 99 Pfam PF09682 Bacteriophage holin of superfamily 6 (Holin_LLH) 11 95 1.0E-7 T 28-03-2018 IPR010026 Phage holin, LL-H family CIG75_RS14285 c12c03d75944e5e65c1d1f7f43fbbd01 214 Pfam PF07947 YhhN family 27 213 2.1E-43 T 28-03-2018 IPR012506 YhhN-like GO:0016021 CIG75_RS10120 81dd635e4fcb7be47e3635d3eb0a376f 199 Gene3D G3DSA:1.10.10.10 2 180 3.3E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS10120 81dd635e4fcb7be47e3635d3eb0a376f 199 SUPERFAMILY SSF46785 10 83 1.34E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS10120 81dd635e4fcb7be47e3635d3eb0a376f 199 Pfam PF12840 Helix-turn-helix domain 15 71 2.3E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS08775 d66a8466b984c4e02a03b45fc574a8d1 155 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 14 150 3.1E-59 T 28-03-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CIG75_RS08775 d66a8466b984c4e02a03b45fc574a8d1 155 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 13 151 7.0E-60 T 28-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CIG75_RS08775 d66a8466b984c4e02a03b45fc574a8d1 155 SUPERFAMILY SSF52121 4 154 5.36E-64 T 28-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CIG75_RS08775 d66a8466b984c4e02a03b45fc574a8d1 155 Gene3D G3DSA:3.40.50.960 70 155 2.5E-42 T 28-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CIG75_RS08775 d66a8466b984c4e02a03b45fc574a8d1 155 Gene3D G3DSA:3.40.50.960 3 69 1.9E-23 T 28-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CIG75_RS08775 d66a8466b984c4e02a03b45fc574a8d1 155 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 9 154 31.541 T 28-03-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CIG75_RS01720 9bfa09ea7067ae7d7379fd8467089736 123 SUPERFAMILY SSF52172 5 121 1.05E-38 T 28-03-2018 IPR011006 CheY-like superfamily CIG75_RS01720 9bfa09ea7067ae7d7379fd8467089736 123 Pfam PF00072 Response regulator receiver domain 8 118 1.3E-32 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CIG75_RS01720 9bfa09ea7067ae7d7379fd8467089736 123 Gene3D G3DSA:3.40.50.2300 1 123 1.8E-37 T 28-03-2018 CIG75_RS01720 9bfa09ea7067ae7d7379fd8467089736 123 SMART SM00448 6 117 2.4E-35 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CIG75_RS07755 fd70fde4c6fde66fc28ca37b5d2b894d 152 Gene3D G3DSA:3.40.1550.10 1 152 4.9E-32 T 28-03-2018 IPR028976 CheC-like domain CIG75_RS07755 fd70fde4c6fde66fc28ca37b5d2b894d 152 SUPERFAMILY SSF103039 1 149 3.01E-31 T 28-03-2018 IPR028976 CheC-like domain CIG75_RS07755 fd70fde4c6fde66fc28ca37b5d2b894d 152 Pfam PF13690 Chemotaxis phosphatase CheX 44 124 5.3E-17 T 28-03-2018 IPR028051 Chemotaxis phosphatase CheX-like domain CIG75_RS15525 9eb2c66dd6d23ba189c66a24cef02dea 121 PIRSF PIRSF002030 1 121 4.9E-44 T 28-03-2018 IPR016339 Truncated hemoglobin, group 1 CIG75_RS15525 9eb2c66dd6d23ba189c66a24cef02dea 121 Gene3D G3DSA:1.10.490.10 1 121 7.8E-37 T 28-03-2018 CIG75_RS15525 9eb2c66dd6d23ba189c66a24cef02dea 121 Pfam PF01152 Bacterial-like globin 6 118 2.7E-25 T 28-03-2018 IPR001486 Truncated hemoglobin GO:0019825 CIG75_RS15525 9eb2c66dd6d23ba189c66a24cef02dea 121 SUPERFAMILY SSF46458 3 119 3.71E-35 T 28-03-2018 IPR009050 Globin-like CIG75_RS14695 db5f7a00394fa3c45efadbf89f62f13a 160 Pfam PF14242 Domain of unknown function (DUF4342) 54 127 7.6E-18 T 28-03-2018 IPR025642 Domain of unknown function DUF4342 CIG75_RS14695 db5f7a00394fa3c45efadbf89f62f13a 160 Gene3D G3DSA:1.10.8.10 1 71 4.0E-7 T 28-03-2018 CIG75_RS04890 431b5ad02db75ecf1b89c1a069502a4d 149 SMART SM00947 1 141 2.2E-24 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CIG75_RS04890 431b5ad02db75ecf1b89c1a069502a4d 149 Pfam PF00484 Carbonic anhydrase 2 137 4.5E-15 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CIG75_RS04890 431b5ad02db75ecf1b89c1a069502a4d 149 SUPERFAMILY SSF53056 1 140 5.49E-32 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CIG75_RS04890 431b5ad02db75ecf1b89c1a069502a4d 149 Gene3D G3DSA:3.40.1050.10 1 147 2.2E-27 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CIG75_RS16540 7f0e17a73b33e05750eb1de95f758b2c 1272 Gene3D G3DSA:3.40.50.300 461 921 1.5E-43 T 28-03-2018 CIG75_RS16540 7f0e17a73b33e05750eb1de95f758b2c 1272 SUPERFAMILY SSF52540 829 868 2.94E-108 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS16540 7f0e17a73b33e05750eb1de95f758b2c 1272 SUPERFAMILY SSF52540 206 223 2.94E-108 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS16540 7f0e17a73b33e05750eb1de95f758b2c 1272 SUPERFAMILY SSF52540 341 787 2.94E-108 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS16540 7f0e17a73b33e05750eb1de95f758b2c 1272 SUPERFAMILY SSF52540 17 178 2.94E-108 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS16540 7f0e17a73b33e05750eb1de95f758b2c 1272 Gene3D G3DSA:3.90.320.10 969 1235 4.5E-26 T 28-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 CIG75_RS16540 7f0e17a73b33e05750eb1de95f758b2c 1272 Gene3D G3DSA:3.40.50.300 11 460 7.6E-43 T 28-03-2018 CIG75_RS16540 7f0e17a73b33e05750eb1de95f758b2c 1272 SUPERFAMILY SSF52980 996 1198 1.98E-19 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CIG75_RS16540 7f0e17a73b33e05750eb1de95f758b2c 1272 Pfam PF13361 UvrD-like helicase C-terminal domain 459 850 3.7E-30 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CIG75_RS16540 7f0e17a73b33e05750eb1de95f758b2c 1272 Pfam PF00580 UvrD/REP helicase N-terminal domain 19 448 2.2E-55 T 28-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 CIG75_RS16540 7f0e17a73b33e05750eb1de95f758b2c 1272 Pfam PF12705 PD-(D/E)XK nuclease superfamily 997 1252 1.3E-27 T 28-03-2018 CIG75_RS00865 9857ba940c35b2af6225d4dee5c49932 394 Gene3D G3DSA:3.40.50.1260 4 179 7.5E-65 T 28-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS00865 9857ba940c35b2af6225d4dee5c49932 394 PRINTS PR00477 Phosphoglycerate kinase family signature 109 124 6.8E-77 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS00865 9857ba940c35b2af6225d4dee5c49932 394 PRINTS PR00477 Phosphoglycerate kinase family signature 190 209 6.8E-77 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS00865 9857ba940c35b2af6225d4dee5c49932 394 PRINTS PR00477 Phosphoglycerate kinase family signature 311 336 6.8E-77 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS00865 9857ba940c35b2af6225d4dee5c49932 394 PRINTS PR00477 Phosphoglycerate kinase family signature 31 53 6.8E-77 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS00865 9857ba940c35b2af6225d4dee5c49932 394 PRINTS PR00477 Phosphoglycerate kinase family signature 137 159 6.8E-77 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS00865 9857ba940c35b2af6225d4dee5c49932 394 PRINTS PR00477 Phosphoglycerate kinase family signature 167 189 6.8E-77 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS00865 9857ba940c35b2af6225d4dee5c49932 394 PRINTS PR00477 Phosphoglycerate kinase family signature 344 355 6.8E-77 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS00865 9857ba940c35b2af6225d4dee5c49932 394 PRINTS PR00477 Phosphoglycerate kinase family signature 367 384 6.8E-77 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS00865 9857ba940c35b2af6225d4dee5c49932 394 PRINTS PR00477 Phosphoglycerate kinase family signature 10 26 6.8E-77 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS00865 9857ba940c35b2af6225d4dee5c49932 394 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 3 391 36.126 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS00865 9857ba940c35b2af6225d4dee5c49932 394 Gene3D G3DSA:3.40.50.1260 180 379 4.9E-69 T 28-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS00865 9857ba940c35b2af6225d4dee5c49932 394 SUPERFAMILY SSF53748 1 390 2.94E-131 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS00865 9857ba940c35b2af6225d4dee5c49932 394 PIRSF PIRSF000724 1 394 3.7E-128 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS00865 9857ba940c35b2af6225d4dee5c49932 394 Pfam PF00162 Phosphoglycerate kinase 6 380 9.2E-136 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CIG75_RS04865 8ab0bf61a9069a74302a6c24072dcefd 121 SUPERFAMILY SSF54593 9 120 2.55E-21 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CIG75_RS04865 8ab0bf61a9069a74302a6c24072dcefd 121 Gene3D G3DSA:3.10.180.10 6 121 9.0E-18 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CIG75_RS03365 30ff08cfb1e1f445645f9d4972e88d7e 372 SUPERFAMILY SSF54593 12 359 1.1E-89 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CIG75_RS03365 30ff08cfb1e1f445645f9d4972e88d7e 372 PIRSF PIRSF009283 9 372 2.1E-126 T 28-03-2018 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 CIG75_RS03365 30ff08cfb1e1f445645f9d4972e88d7e 372 Gene3D G3DSA:3.10.180.10 175 372 3.8E-70 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CIG75_RS03365 30ff08cfb1e1f445645f9d4972e88d7e 372 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 178 326 9.0E-20 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CIG75_RS03365 30ff08cfb1e1f445645f9d4972e88d7e 372 Pfam PF14696 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal 21 153 1.0E-8 T 28-03-2018 CIG75_RS03365 30ff08cfb1e1f445645f9d4972e88d7e 372 TIGRFAM TIGR01263 4HPPD: 4-hydroxyphenylpyruvate dioxygenase 20 372 1.2E-126 T 28-03-2018 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 CIG75_RS03365 30ff08cfb1e1f445645f9d4972e88d7e 372 Gene3D G3DSA:3.10.180.10 5 174 2.5E-29 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CIG75_RS12205 fc362bfb6ab8f5028889ededee6385fd 672 Pfam PF02120 Flagellar hook-length control protein FliK 585 649 1.6E-8 T 28-03-2018 IPR021136 Flagellar hook-length control protein-like, C-terminal CIG75_RS10565 a6299d35b32f9700d1b97a9b88491659 100 Gene3D G3DSA:1.20.120.330 14 96 1.7E-4 T 28-03-2018 CIG75_RS12405 7c6c1b18c93466f4e1bd5025d7a43356 269 Gene3D G3DSA:3.40.1090.10 2 248 2.5E-48 T 28-03-2018 CIG75_RS12405 7c6c1b18c93466f4e1bd5025d7a43356 269 Pfam PF01734 Patatin-like phospholipase 8 166 6.4E-22 T 28-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 CIG75_RS12405 7c6c1b18c93466f4e1bd5025d7a43356 269 SUPERFAMILY SSF52151 2 253 6.02E-58 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CIG75_RS16435 11560481dbea50a60df44bdac2d12717 225 PIRSF PIRSF001467 48 225 1.9E-46 T 28-03-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 CIG75_RS16435 11560481dbea50a60df44bdac2d12717 225 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 68 221 3.9E-44 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CIG75_RS16435 11560481dbea50a60df44bdac2d12717 225 Gene3D G3DSA:2.40.100.10 45 225 6.0E-61 T 28-03-2018 IPR029000 Cyclophilin-like domain CIG75_RS16435 11560481dbea50a60df44bdac2d12717 225 SUPERFAMILY SSF50891 62 222 1.61E-53 T 28-03-2018 IPR029000 Cyclophilin-like domain CIG75_RS16435 11560481dbea50a60df44bdac2d12717 225 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 146 161 3.1E-17 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CIG75_RS16435 11560481dbea50a60df44bdac2d12717 225 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 81 96 3.1E-17 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CIG75_RS16435 11560481dbea50a60df44bdac2d12717 225 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 107 119 3.1E-17 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CIG75_RS09160 6c722bc72ace40e4d21cfdc759d6b8d7 160 SUPERFAMILY SSF55811 12 144 8.39E-25 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CIG75_RS09160 6c722bc72ace40e4d21cfdc759d6b8d7 160 Gene3D G3DSA:3.90.79.10 5 157 3.3E-23 T 28-03-2018 CIG75_RS09160 6c722bc72ace40e4d21cfdc759d6b8d7 160 ProSitePatterns PS00893 Nudix box signature. 42 63 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CIG75_RS09160 6c722bc72ace40e4d21cfdc759d6b8d7 160 Pfam PF00293 NUDIX domain 14 134 1.9E-13 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CIG75_RS02630 7edb9573b17af31405e20c7d8878cf52 1147 SUPERFAMILY SSF52540 188 267 3.9E-6 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS02630 7edb9573b17af31405e20c7d8878cf52 1147 SUPERFAMILY SSF52540 332 420 3.9E-6 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS02630 7edb9573b17af31405e20c7d8878cf52 1147 SUPERFAMILY SSF52540 60 118 3.9E-6 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS02630 7edb9573b17af31405e20c7d8878cf52 1147 Gene3D G3DSA:3.40.50.300 44 1146 5.6E-4 T 28-03-2018 CIG75_RS09860 e3481834f51c45b458d2c80a28ad10ef 270 Pfam PF00696 Amino acid kinase family 2 237 3.0E-27 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CIG75_RS09860 e3481834f51c45b458d2c80a28ad10ef 270 SUPERFAMILY SSF53633 2 260 2.49E-30 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CIG75_RS09860 e3481834f51c45b458d2c80a28ad10ef 270 PRINTS PR00474 Glutamate 5-kinase family signature 151 178 7.5E-9 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CIG75_RS09860 e3481834f51c45b458d2c80a28ad10ef 270 PRINTS PR00474 Glutamate 5-kinase family signature 41 55 7.5E-9 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CIG75_RS09860 e3481834f51c45b458d2c80a28ad10ef 270 PRINTS PR00474 Glutamate 5-kinase family signature 211 231 7.5E-9 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CIG75_RS09860 e3481834f51c45b458d2c80a28ad10ef 270 PRINTS PR00474 Glutamate 5-kinase family signature 118 139 7.5E-9 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CIG75_RS09860 e3481834f51c45b458d2c80a28ad10ef 270 Gene3D G3DSA:3.40.1160.10 1 263 2.0E-31 T 28-03-2018 CIG75_RS04600 08011303977fd2b3a6caf444754f8334 289 Gene3D G3DSA:3.40.50.720 1 289 1.3E-30 T 28-03-2018 CIG75_RS04600 08011303977fd2b3a6caf444754f8334 289 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 113 1.9E-6 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CIG75_RS04600 08011303977fd2b3a6caf444754f8334 289 SUPERFAMILY SSF51735 2 287 7.75E-35 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS16650 33ca24d0dc0b5bc5aba58e10078011a2 149 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 13 118 1.2E-15 T 28-03-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA CIG75_RS16650 33ca24d0dc0b5bc5aba58e10078011a2 149 SUPERFAMILY SSF158622 8 128 8.24E-19 T 28-03-2018 IPR023378 YheA/YmcA-like domain CIG75_RS16650 33ca24d0dc0b5bc5aba58e10078011a2 149 Gene3D G3DSA:1.20.1500.10 11 121 1.8E-19 T 28-03-2018 IPR023378 YheA/YmcA-like domain CIG75_RS16650 33ca24d0dc0b5bc5aba58e10078011a2 149 PIRSF PIRSF021287 4 128 8.3E-18 T 28-03-2018 IPR016783 Biofilm formation YmcA CIG75_RS14550 14135c28247a343bad6712fdcccdfb85 393 Gene3D G3DSA:3.90.550.10 27 284 2.7E-31 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CIG75_RS14550 14135c28247a343bad6712fdcccdfb85 393 Pfam PF00535 Glycosyl transferase family 2 45 176 1.1E-20 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CIG75_RS14550 14135c28247a343bad6712fdcccdfb85 393 SUPERFAMILY SSF53448 40 264 3.56E-35 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CIG75_RS19890 2cfc2f07f0da568cdb9cbcbdadcc02ae 178 Gene3D G3DSA:4.10.860.10 116 176 3.1E-11 T 28-03-2018 IPR001943 UVR domain GO:0005515 CIG75_RS19890 2cfc2f07f0da568cdb9cbcbdadcc02ae 178 SUPERFAMILY SSF46600 136 172 2.22E-5 T 28-03-2018 IPR001943 UVR domain GO:0005515 CIG75_RS19890 2cfc2f07f0da568cdb9cbcbdadcc02ae 178 Pfam PF02151 UvrB/uvrC motif 138 172 8.4E-5 T 28-03-2018 IPR001943 UVR domain GO:0005515 CIG75_RS19890 2cfc2f07f0da568cdb9cbcbdadcc02ae 178 PIRSF PIRSF015034 1 177 8.3E-64 T 28-03-2018 IPR025542 YacH protein CIG75_RS00585 a53813402ae7c458571801c43ae4a04e 260 Pfam PF01987 Mitochondrial biogenesis AIM24 51 249 1.5E-36 T 28-03-2018 IPR002838 Mitochondrial biogenesis protein AIM24 CIG75_RS00585 a53813402ae7c458571801c43ae4a04e 260 Gene3D G3DSA:3.60.160.10 35 257 2.3E-42 T 28-03-2018 IPR002838 Mitochondrial biogenesis protein AIM24 CIG75_RS00585 a53813402ae7c458571801c43ae4a04e 260 SUPERFAMILY SSF51219 44 249 9.68E-47 T 28-03-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain CIG75_RS18155 148da1dc0afcaefa8263f653526e3249 348 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 211 231 - T 28-03-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 CIG75_RS18155 148da1dc0afcaefa8263f653526e3249 348 Gene3D G3DSA:3.10.50.40 171 299 5.2E-37 T 28-03-2018 CIG75_RS18155 148da1dc0afcaefa8263f653526e3249 348 Pfam PF13624 SurA N-terminal domain 80 154 2.3E-8 T 28-03-2018 CIG75_RS18155 148da1dc0afcaefa8263f653526e3249 348 Gene3D G3DSA:1.10.4030.10 50 160 1.9E-13 T 28-03-2018 CIG75_RS18155 148da1dc0afcaefa8263f653526e3249 348 SUPERFAMILY SSF54534 152 272 1.57E-29 T 28-03-2018 CIG75_RS18155 148da1dc0afcaefa8263f653526e3249 348 SUPERFAMILY SSF109998 54 210 2.75E-28 T 28-03-2018 IPR027304 Trigger factor/SurA domain CIG75_RS18155 148da1dc0afcaefa8263f653526e3249 348 Pfam PF13616 PPIC-type PPIASE domain 180 274 2.6E-25 T 28-03-2018 CIG75_RS04085 1191166fa7506c680ae5d4fae2ab0cc6 501 Gene3D G3DSA:3.40.309.10 285 482 2.3E-75 T 28-03-2018 CIG75_RS04085 1191166fa7506c680ae5d4fae2ab0cc6 501 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 296 307 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CIG75_RS04085 1191166fa7506c680ae5d4fae2ab0cc6 501 SUPERFAMILY SSF53720 19 500 2.09E-183 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CIG75_RS04085 1191166fa7506c680ae5d4fae2ab0cc6 501 Gene3D G3DSA:3.40.605.10 9 284 3.4E-116 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CIG75_RS04085 1191166fa7506c680ae5d4fae2ab0cc6 501 Pfam PF00171 Aldehyde dehydrogenase family 31 496 2.5E-190 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CIG75_RS04085 1191166fa7506c680ae5d4fae2ab0cc6 501 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 268 275 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CIG75_RS10715 d75ce82c70d557f42cb5409684f7f01b 363 SUPERFAMILY SSF51735 5 289 9.17E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS10715 d75ce82c70d557f42cb5409684f7f01b 363 Pfam PF07993 Male sterility protein 8 240 2.2E-45 T 28-03-2018 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 CIG75_RS10715 d75ce82c70d557f42cb5409684f7f01b 363 Gene3D G3DSA:3.40.50.720 2 356 1.1E-38 T 28-03-2018 CIG75_RS17105 80b3341595904246b32000cfdaac1e15 268 Pfam PF08543 Phosphomethylpyrimidine kinase 13 256 1.5E-101 T 28-03-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 CIG75_RS17105 80b3341595904246b32000cfdaac1e15 268 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 6 258 4.1E-108 T 28-03-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CIG75_RS17105 80b3341595904246b32000cfdaac1e15 268 SUPERFAMILY SSF53613 1 261 2.03E-84 T 28-03-2018 IPR029056 Ribokinase-like CIG75_RS17105 80b3341595904246b32000cfdaac1e15 268 Gene3D G3DSA:3.40.1190.20 1 268 4.2E-67 T 28-03-2018 IPR029056 Ribokinase-like CIG75_RS14665 7d86f929e0bccfd4cb8c64321a0dbb3b 270 Gene3D G3DSA:3.20.20.70 1 249 5.7E-6 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CIG75_RS14665 7d86f929e0bccfd4cb8c64321a0dbb3b 270 Pfam PF03618 Kinase/pyrophosphorylase 5 260 2.3E-99 T 28-03-2018 IPR005177 Bifunctional kinase-pyrophosphorylase GO:0005524|GO:0016772 CIG75_RS14665 7d86f929e0bccfd4cb8c64321a0dbb3b 270 Hamap MF_00921 Putative pyruvate, phosphate dikinase regulatory protein. 3 265 59.219 T 28-03-2018 IPR026565 Putative pyruvate, phosphate dikinase regulatory protein CIG75_RS04490 fb891c182674dff9f1abdb7560885741 156 PIRSF PIRSF021700 1 156 1.8E-66 T 28-03-2018 IPR009725 Predicted 3-demethylubiquinone-9 3-methyltransferase CIG75_RS04490 fb891c182674dff9f1abdb7560885741 156 Gene3D G3DSA:3.10.180.10 1 126 7.4E-25 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CIG75_RS04490 fb891c182674dff9f1abdb7560885741 156 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 2 116 5.0E-49 T 28-03-2018 IPR028973 PhnB-like CIG75_RS04490 fb891c182674dff9f1abdb7560885741 156 SUPERFAMILY SSF54593 3 154 8.97E-51 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CIG75_RS16570 6f3768edd0591466e14f594c6261acee 318 Pfam PF04055 Radical SAM superfamily 53 215 7.3E-17 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CIG75_RS16570 6f3768edd0591466e14f594c6261acee 318 SMART SM00729 33 260 1.5E-38 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CIG75_RS16570 6f3768edd0591466e14f594c6261acee 318 Pfam PF16199 Radical_SAM C-terminal domain 221 304 7.0E-25 T 28-03-2018 IPR032432 Radical SAM, C-terminal extension Reactome: R-HSA-3214847 CIG75_RS16570 6f3768edd0591466e14f594c6261acee 318 Gene3D G3DSA:3.20.20.70 10 283 1.4E-37 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CIG75_RS16570 6f3768edd0591466e14f594c6261acee 318 SUPERFAMILY SSF102114 9 310 4.58E-54 T 28-03-2018 CIG75_RS16570 6f3768edd0591466e14f594c6261acee 318 TIGRFAM TIGR01212 TIGR01212: radical SAM protein, TIGR01212 family 16 314 5.5E-124 T 28-03-2018 IPR005911 Protein YhcC-like GO:0051536 CIG75_RS09975 e30968c838e01946998b3ce0d0db8bcf 252 Hamap MF_00060 5'/3'-nucleotidase SurE [surE]. 1 252 36.672 T 28-03-2018 IPR030048 Survival protein SurE GO:0008252 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 CIG75_RS09975 e30968c838e01946998b3ce0d0db8bcf 252 SUPERFAMILY SSF64167 1 251 4.71E-84 T 28-03-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 CIG75_RS09975 e30968c838e01946998b3ce0d0db8bcf 252 TIGRFAM TIGR00087 surE: 5'/3'-nucleotidase SurE 1 238 1.7E-74 T 28-03-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 CIG75_RS09975 e30968c838e01946998b3ce0d0db8bcf 252 Gene3D G3DSA:3.40.1210.10 1 252 3.1E-93 T 28-03-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 CIG75_RS09975 e30968c838e01946998b3ce0d0db8bcf 252 Pfam PF01975 Survival protein SurE 3 188 1.2E-64 T 28-03-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 CIG75_RS00825 2daa5c663784f9b5d4582093f1a07f88 132 Gene3D G3DSA:3.30.1330.40 2 131 1.5E-21 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CIG75_RS00825 2daa5c663784f9b5d4582093f1a07f88 132 SUPERFAMILY SSF55298 7 131 5.18E-26 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CIG75_RS00825 2daa5c663784f9b5d4582093f1a07f88 132 Pfam PF01042 Endoribonuclease L-PSP 16 130 3.7E-17 T 28-03-2018 IPR006175 YjgF/YER057c/UK114 family CIG75_RS05695 18631d0607d682a424e9635383371ab2 143 Pfam PF00571 CBS domain 71 118 2.8E-13 T 28-03-2018 IPR000644 CBS domain CIG75_RS05695 18631d0607d682a424e9635383371ab2 143 Pfam PF00571 CBS domain 5 54 7.2E-8 T 28-03-2018 IPR000644 CBS domain CIG75_RS05695 18631d0607d682a424e9635383371ab2 143 SUPERFAMILY SSF54631 1 118 6.44E-34 T 28-03-2018 CIG75_RS05695 18631d0607d682a424e9635383371ab2 143 SMART SM00116 10 58 1.4E-4 T 28-03-2018 IPR000644 CBS domain CIG75_RS05695 18631d0607d682a424e9635383371ab2 143 SMART SM00116 76 123 5.5E-10 T 28-03-2018 IPR000644 CBS domain CIG75_RS05695 18631d0607d682a424e9635383371ab2 143 Gene3D G3DSA:3.10.580.10 1 134 6.5E-30 T 28-03-2018 CIG75_RS11880 9cfe6fae938705ccb661cf3350dcb51c 185 SUPERFAMILY SSF55194 3 184 3.14E-72 T 28-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 CIG75_RS11880 9cfe6fae938705ccb661cf3350dcb51c 185 Pfam PF01765 Ribosome recycling factor 21 183 8.2E-65 T 28-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 CIG75_RS11880 9cfe6fae938705ccb661cf3350dcb51c 185 Gene3D G3DSA:3.40.91.10 7 165 3.5E-52 T 28-03-2018 CIG75_RS11880 9cfe6fae938705ccb661cf3350dcb51c 185 Hamap MF_00040 Ribosome-recycling factor [frr]. 3 185 28.32 T 28-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 CIG75_RS11880 9cfe6fae938705ccb661cf3350dcb51c 185 TIGRFAM TIGR00496 frr: ribosome recycling factor 11 185 1.5E-71 T 28-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 CIG75_RS10180 8ffd6987beafe49058c9bb86336703e0 648 TIGRFAM TIGR02669 SpoIID_LytB: SpoIID/LytB domain 287 645 1.4E-49 T 28-03-2018 IPR013486 Sporulation stage II protein D, amidase enhancer LytB GO:0030435 CIG75_RS10180 8ffd6987beafe49058c9bb86336703e0 648 Pfam PF08486 Stage II sporulation protein 283 371 4.5E-26 T 28-03-2018 IPR013693 Sporulation stage II protein D, amidase enhancer LytB N-terminal CIG75_RS18810 cf0ce21c241de2487b05f51ac0850c47 400 Gene3D G3DSA:1.20.1250.20 197 398 2.1E-13 T 28-03-2018 CIG75_RS18810 cf0ce21c241de2487b05f51ac0850c47 400 Gene3D G3DSA:1.20.1250.20 10 186 3.4E-21 T 28-03-2018 CIG75_RS18810 cf0ce21c241de2487b05f51ac0850c47 400 PRINTS PR01988 Putative bacilysin exporter bacE signature 161 178 5.1E-5 T 28-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CIG75_RS18810 cf0ce21c241de2487b05f51ac0850c47 400 PRINTS PR01988 Putative bacilysin exporter bacE signature 134 155 5.1E-5 T 28-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CIG75_RS18810 cf0ce21c241de2487b05f51ac0850c47 400 PRINTS PR01988 Putative bacilysin exporter bacE signature 73 91 5.1E-5 T 28-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CIG75_RS18810 cf0ce21c241de2487b05f51ac0850c47 400 Pfam PF07690 Major Facilitator Superfamily 40 354 3.8E-26 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CIG75_RS18810 cf0ce21c241de2487b05f51ac0850c47 400 SUPERFAMILY SSF103473 26 395 6.15E-44 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS17335 72f5603f27fa772c3b2e9f94a145ea0b 462 SUPERFAMILY SSF56059 227 359 3.36E-38 T 28-03-2018 CIG75_RS17335 72f5603f27fa772c3b2e9f94a145ea0b 462 SUPERFAMILY SSF56059 128 200 3.36E-38 T 28-03-2018 CIG75_RS17335 72f5603f27fa772c3b2e9f94a145ea0b 462 Pfam PF13535 ATP-grasp domain 164 335 1.4E-15 T 28-03-2018 CIG75_RS17335 72f5603f27fa772c3b2e9f94a145ea0b 462 Gene3D G3DSA:3.30.470.20 121 446 1.3E-39 T 28-03-2018 CIG75_RS17325 fd0578b381bc9cdf07cfb5f0dda2fc97 424 Pfam PF07690 Major Facilitator Superfamily 40 371 3.2E-26 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CIG75_RS17325 fd0578b381bc9cdf07cfb5f0dda2fc97 424 Gene3D G3DSA:1.20.1250.20 213 423 1.0E-17 T 28-03-2018 CIG75_RS17325 fd0578b381bc9cdf07cfb5f0dda2fc97 424 SUPERFAMILY SSF103473 15 416 1.96E-43 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS17325 fd0578b381bc9cdf07cfb5f0dda2fc97 424 Gene3D G3DSA:1.20.1250.20 19 205 7.1E-19 T 28-03-2018 CIG75_RS03105 67c8f65721a972b7b4b7317553bba634 263 Gene3D G3DSA:2.60.40.10 142 197 0.29 T 28-03-2018 IPR013783 Immunoglobulin-like fold CIG75_RS03105 67c8f65721a972b7b4b7317553bba634 263 Gene3D G3DSA:2.60.40.10 53 141 0.026 T 28-03-2018 IPR013783 Immunoglobulin-like fold CIG75_RS14365 795f5f3dc666c475727d073762323f15 519 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 47 499 7.8E-178 T 28-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 CIG75_RS14365 795f5f3dc666c475727d073762323f15 519 PIRSF PIRSF005690 30 514 7.1E-178 T 28-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 CIG75_RS09420 93d8dc011a76ce391ee7661dc24ef709 276 SUPERFAMILY SSF55681 1 276 8.29E-68 T 28-03-2018 CIG75_RS09420 93d8dc011a76ce391ee7661dc24ef709 276 Gene3D G3DSA:3.30.930.10 1 276 2.0E-55 T 28-03-2018 CIG75_RS09420 93d8dc011a76ce391ee7661dc24ef709 276 Pfam PF03099 Biotin/lipoate A/B protein ligase family 50 187 8.9E-24 T 28-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 CIG75_RS09370 de1adb7190776480d300771672836803 220 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 129 191 6.5E-13 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CIG75_RS09370 de1adb7190776480d300771672836803 220 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 106 186 2.7E-15 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CIG75_RS09370 de1adb7190776480d300771672836803 220 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 191 2.0E-32 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS09370 de1adb7190776480d300771672836803 220 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 1.1E-12 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CIG75_RS09370 de1adb7190776480d300771672836803 220 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 104 117 1.1E-12 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CIG75_RS09370 de1adb7190776480d300771672836803 220 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 153 173 1.1E-12 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CIG75_RS09370 de1adb7190776480d300771672836803 220 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 135 151 1.1E-12 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CIG75_RS09370 de1adb7190776480d300771672836803 220 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 95 194 2.5E-14 T 28-03-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 CIG75_RS09370 de1adb7190776480d300771672836803 220 Gene3D G3DSA:3.40.50.1000 73 220 1.3E-37 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS09370 de1adb7190776480d300771672836803 220 SUPERFAMILY SSF56784 1 219 1.13E-49 T 28-03-2018 IPR023214 HAD-like domain CIG75_RS00915 0a0e6b6a5fb007191589fbd0dacdcd52 122 Pfam PF13788 Domain of unknown function (DUF4180) 10 118 1.3E-40 T 28-03-2018 IPR025438 Domain of unknown function DUF4180 CIG75_RS07880 5ab80449e755c333746206c3157472f8 336 Gene3D G3DSA:3.40.190.10 139 334 8.8E-30 T 28-03-2018 CIG75_RS07880 5ab80449e755c333746206c3157472f8 336 Gene3D G3DSA:3.40.190.10 31 138 7.8E-13 T 28-03-2018 CIG75_RS07880 5ab80449e755c333746206c3157472f8 336 SUPERFAMILY SSF53850 34 272 5.74E-29 T 28-03-2018 CIG75_RS07880 5ab80449e755c333746206c3157472f8 336 Pfam PF09084 NMT1/THI5 like 48 257 3.9E-24 T 28-03-2018 IPR015168 SsuA/THI5-like CIG75_RS13740 bfdc18c7810697b2c0a79f0de5237ea8 66 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 22 31 - T 28-03-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 CIG75_RS13740 bfdc18c7810697b2c0a79f0de5237ea8 66 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 7 61 2.9E-21 T 28-03-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 CIG75_RS09780 9ab941019688e56706b9ceda8a63ae79 106 SUPERFAMILY SSF52821 3 100 5.11E-29 T 28-03-2018 IPR001763 Rhodanese-like domain CIG75_RS09780 9ab941019688e56706b9ceda8a63ae79 106 Pfam PF00581 Rhodanese-like domain 8 99 8.4E-15 T 28-03-2018 IPR001763 Rhodanese-like domain CIG75_RS09780 9ab941019688e56706b9ceda8a63ae79 106 Gene3D G3DSA:3.40.250.10 4 105 2.2E-24 T 28-03-2018 IPR001763 Rhodanese-like domain CIG75_RS09780 9ab941019688e56706b9ceda8a63ae79 106 SMART SM00450 8 103 1.4E-17 T 28-03-2018 IPR001763 Rhodanese-like domain CIG75_RS17575 02981dee16b58eee40ed8dea5775de2d 234 SMART SM00382 30 217 8.3E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS17575 02981dee16b58eee40ed8dea5775de2d 234 Gene3D G3DSA:3.40.50.300 1 232 2.2E-65 T 28-03-2018 CIG75_RS17575 02981dee16b58eee40ed8dea5775de2d 234 Pfam PF00005 ABC transporter 23 169 1.8E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS17575 02981dee16b58eee40ed8dea5775de2d 234 SUPERFAMILY SSF52540 1 225 2.13E-74 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS17575 02981dee16b58eee40ed8dea5775de2d 234 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CIG75_RS11075 209864be6f3e518b344550bf349f2f77 928 Pfam PF07090 Putative glutamine amidotransferase 601 674 8.4E-7 T 28-03-2018 IPR010768 Putative glutamine amidotransferase CIG75_RS11075 209864be6f3e518b344550bf349f2f77 928 Gene3D G3DSA:2.60.40.10 217 277 0.0018 T 28-03-2018 IPR013783 Immunoglobulin-like fold CIG75_RS11075 209864be6f3e518b344550bf349f2f77 928 SUPERFAMILY SSF52317 274 402 8.55E-43 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CIG75_RS11075 209864be6f3e518b344550bf349f2f77 928 SUPERFAMILY SSF52317 579 675 8.55E-43 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CIG75_RS11075 209864be6f3e518b344550bf349f2f77 928 Gene3D G3DSA:3.40.50.880 278 677 4.0E-36 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CIG75_RS11075 209864be6f3e518b344550bf349f2f77 928 Pfam PF13519 von Willebrand factor type A domain 68 163 2.7E-8 T 28-03-2018 IPR002035 von Willebrand factor, type A CIG75_RS11075 209864be6f3e518b344550bf349f2f77 928 SUPERFAMILY SSF53300 408 564 3.76E-33 T 28-03-2018 IPR002035 von Willebrand factor, type A CIG75_RS11075 209864be6f3e518b344550bf349f2f77 928 SMART SM00327 65 220 0.014 T 28-03-2018 IPR002035 von Willebrand factor, type A CIG75_RS11075 209864be6f3e518b344550bf349f2f77 928 SMART SM00327 406 577 3.6E-21 T 28-03-2018 IPR002035 von Willebrand factor, type A CIG75_RS11075 209864be6f3e518b344550bf349f2f77 928 Pfam PF00092 von Willebrand factor type A domain 409 569 3.5E-22 T 28-03-2018 IPR002035 von Willebrand factor, type A CIG75_RS11075 209864be6f3e518b344550bf349f2f77 928 Gene3D G3DSA:3.40.50.410 65 216 1.8E-11 T 28-03-2018 IPR002035 von Willebrand factor, type A CIG75_RS11075 209864be6f3e518b344550bf349f2f77 928 SUPERFAMILY SSF53300 67 206 4.45E-13 T 28-03-2018 IPR002035 von Willebrand factor, type A CIG75_RS02920 f02027be6eef0ecda16809c73a172cb4 193 Pfam PF02342 TerD domain 1 188 3.1E-83 T 28-03-2018 IPR003325 TerD domain GO:0006950 CIG75_RS02920 f02027be6eef0ecda16809c73a172cb4 193 Gene3D G3DSA:2.60.60.30 18 187 9.5E-63 T 28-03-2018 CIG75_RS11510 8fbdaffdaf1f58543f9a5596d887ca2f 285 Pfam PF01909 Nucleotidyltransferase domain 31 62 6.7E-5 T 28-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 CIG75_RS11510 8fbdaffdaf1f58543f9a5596d887ca2f 285 Pfam PF13427 Domain of unknown function (DUF4111) 183 244 1.0E-10 T 28-03-2018 IPR025184 Domain of unknown function DUF4111 CIG75_RS11510 8fbdaffdaf1f58543f9a5596d887ca2f 285 Gene3D G3DSA:3.30.460.10 5 234 8.7E-10 T 28-03-2018 CIG75_RS11510 8fbdaffdaf1f58543f9a5596d887ca2f 285 SUPERFAMILY SSF81301 30 83 3.27E-8 T 28-03-2018 CIG75_RS19075 de37d295d1fbe33f3df8cb4f63f4ad6e 213 Gene3D G3DSA:1.10.10.10 146 210 1.3E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS15780 0472549a293393467f895e3f7c8fd952 433 TIGRFAM TIGR03332 salvage_mtnW: 2,3-diketo-5-methylthiopentyl-1-phosphate enolase 36 431 1.7E-165 T 28-03-2018 IPR017717 2,3-diketo-5-methylthiopentyl-1-phosphate enolase GO:0000287|GO:0019509|GO:0043715 KEGG: 00270+5.3.2.5|MetaCyc: PWY-4361 CIG75_RS15780 0472549a293393467f895e3f7c8fd952 433 Pfam PF02788 Ribulose bisphosphate carboxylase large chain, N-terminal domain 34 140 4.1E-7 T 28-03-2018 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 CIG75_RS15780 0472549a293393467f895e3f7c8fd952 433 SUPERFAMILY SSF51649 145 432 2.49E-90 T 28-03-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 CIG75_RS15780 0472549a293393467f895e3f7c8fd952 433 Pfam PF00016 Ribulose bisphosphate carboxylase large chain, catalytic domain 151 431 1.3E-51 T 28-03-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 CIG75_RS15780 0472549a293393467f895e3f7c8fd952 433 SUPERFAMILY SSF54966 21 147 2.09E-28 T 28-03-2018 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 CIG75_RS15780 0472549a293393467f895e3f7c8fd952 433 Gene3D G3DSA:3.30.70.150 26 145 2.0E-27 T 28-03-2018 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 CIG75_RS15780 0472549a293393467f895e3f7c8fd952 433 Gene3D G3DSA:3.20.20.110 147 432 3.8E-97 T 28-03-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 CIG75_RS02330 84d06215643d36434ddb9ed681a10c35 196 Gene3D G3DSA:3.40.50.2020 7 196 8.5E-25 T 28-03-2018 CIG75_RS02330 84d06215643d36434ddb9ed681a10c35 196 SUPERFAMILY SSF53271 35 195 1.1E-21 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CIG75_RS09090 f7c88c689822f9b7791d87af8e510869 236 Gene3D G3DSA:3.90.1720.10 108 236 1.7E-42 T 28-03-2018 CIG75_RS09090 f7c88c689822f9b7791d87af8e510869 236 Pfam PF00877 NlpC/P60 family 129 233 8.8E-33 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CIG75_RS09090 f7c88c689822f9b7791d87af8e510869 236 SUPERFAMILY SSF54001 120 235 2.94E-45 T 28-03-2018 CIG75_RS06250 ab88e39cb97c404b65d76fdb19d9c8a2 351 Pfam PF09580 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) 263 328 4.1E-7 T 28-03-2018 IPR019076 Sporulation lipoprotein YhcN/YlaJ-like CIG75_RS06250 ab88e39cb97c404b65d76fdb19d9c8a2 351 Pfam PF09580 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) 15 149 2.9E-6 T 28-03-2018 IPR019076 Sporulation lipoprotein YhcN/YlaJ-like CIG75_RS00450 c400a48331ff6771b78c7399bf79b975 332 SUPERFAMILY SSF51679 4 330 1.44E-82 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CIG75_RS00450 c400a48331ff6771b78c7399bf79b975 332 Gene3D G3DSA:3.20.20.30 3 332 9.3E-75 T 28-03-2018 CIG75_RS00450 c400a48331ff6771b78c7399bf79b975 332 Pfam PF00296 Luciferase-like monooxygenase 18 306 7.2E-33 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CIG75_RS00450 c400a48331ff6771b78c7399bf79b975 332 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 5 329 9.9E-130 T 28-03-2018 IPR019949 Luciferase family oxidoreductase, group 1 CIG75_RS06015 e11eb4b2c1bbef35b6da302835423ff9 354 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 21 88 2.3E-23 T 28-03-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 CIG75_RS06015 e11eb4b2c1bbef35b6da302835423ff9 354 SUPERFAMILY SSF55681 93 351 4.73E-79 T 28-03-2018 CIG75_RS06015 e11eb4b2c1bbef35b6da302835423ff9 354 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 40 351 2.5E-104 T 28-03-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CIG75_RS06015 e11eb4b2c1bbef35b6da302835423ff9 354 Pfam PF01409 tRNA synthetases class II core domain (F) 93 350 6.9E-101 T 28-03-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 CIG75_RS06015 e11eb4b2c1bbef35b6da302835423ff9 354 SUPERFAMILY SSF46589 14 100 1.46E-20 T 28-03-2018 IPR010978 tRNA-binding arm GO:0000166 CIG75_RS06015 e11eb4b2c1bbef35b6da302835423ff9 354 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 9 350 47.851 T 28-03-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 CIG75_RS06015 e11eb4b2c1bbef35b6da302835423ff9 354 Gene3D G3DSA:3.30.930.10 8 354 2.5E-91 T 28-03-2018 CIG75_RS04100 65d762a7d968726d98257264ad836bc0 344 SUPERFAMILY SSF51679 1 343 1.83E-93 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CIG75_RS04100 65d762a7d968726d98257264ad836bc0 344 Gene3D G3DSA:3.20.20.30 1 344 8.7E-92 T 28-03-2018 CIG75_RS04100 65d762a7d968726d98257264ad836bc0 344 Pfam PF00296 Luciferase-like monooxygenase 1 318 2.4E-81 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CIG75_RS03380 d237ea508f57316000846b1b0ffd0dce 181 Pfam PF12793 Sugar transport-related sRNA regulator N-term 84 179 3.7E-26 T 28-03-2018 IPR025370 Transcriptional regulator SgrR, N-terminal HTH domain CIG75_RS07700 19b9f1942fa4fe2645896a1f10cf37d5 147 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 15 134 8.8E-25 T 28-03-2018 IPR005031 Coenzyme Q-binding protein COQ10, START domain Reactome: R-HSA-611105 CIG75_RS07700 19b9f1942fa4fe2645896a1f10cf37d5 147 SUPERFAMILY SSF55961 1 144 4.62E-31 T 28-03-2018 CIG75_RS07700 19b9f1942fa4fe2645896a1f10cf37d5 147 Gene3D G3DSA:3.30.530.20 1 146 1.2E-28 T 28-03-2018 IPR023393 START-like domain CIG75_RS16760 50fd7b1ad5af5448f9c0fe1ab72a645c 69 Gene3D G3DSA:1.10.260.40 3 62 2.1E-13 T 28-03-2018 CIG75_RS16760 50fd7b1ad5af5448f9c0fe1ab72a645c 69 SUPERFAMILY SSF47413 12 62 1.45E-11 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CIG75_RS16760 50fd7b1ad5af5448f9c0fe1ab72a645c 69 Pfam PF01381 Helix-turn-helix 12 58 4.0E-9 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS16760 50fd7b1ad5af5448f9c0fe1ab72a645c 69 SMART SM00530 5 58 1.0E-8 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS09915 e2700f328457ccf1952b2db50df56438 318 Pfam PF00395 S-layer homology domain 155 199 1.2E-8 T 28-03-2018 IPR001119 S-layer homology domain CIG75_RS09915 e2700f328457ccf1952b2db50df56438 318 Pfam PF14343 PrcB C-terminal 252 307 5.8E-9 T 28-03-2018 IPR025748 PrcB C-terminal domain CIG75_RS08005 aab33e08a9bcbd7c88bdd0cb9ef03f25 403 Pfam PF02687 FtsX-like permease family 298 395 1.7E-10 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CIG75_RS00545 539d8a6470b609fd28625c3d2cd5e86f 454 Pfam PF07435 YycH protein 3 430 1.0E-37 T 28-03-2018 IPR009996 Regulatory protein YycH CIG75_RS13915 ccc18a27249461153830b73b3d6e39f0 168 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 127 140 7.8E-15 T 28-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CIG75_RS13915 ccc18a27249461153830b73b3d6e39f0 168 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 95 108 7.8E-15 T 28-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CIG75_RS13915 ccc18a27249461153830b73b3d6e39f0 168 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 112 126 7.8E-15 T 28-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CIG75_RS13915 ccc18a27249461153830b73b3d6e39f0 168 SUPERFAMILY SSF51230 90 165 5.5E-21 T 28-03-2018 IPR011053 Single hybrid motif CIG75_RS13915 ccc18a27249461153830b73b3d6e39f0 168 Gene3D G3DSA:2.40.50.100 33 167 3.8E-15 T 28-03-2018 CIG75_RS13915 ccc18a27249461153830b73b3d6e39f0 168 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 3 166 4.1E-51 T 28-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CIG75_RS13915 ccc18a27249461153830b73b3d6e39f0 168 Pfam PF00364 Biotin-requiring enzyme 92 163 1.0E-19 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CIG75_RS09050 c37c304441a18cbf153e9746d06ae909 462 Gene3D G3DSA:3.30.2290.10 2 221 2.2E-42 T 28-03-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal domain CIG75_RS09050 c37c304441a18cbf153e9746d06ae909 462 SUPERFAMILY SSF111283 2 459 6.54E-122 T 28-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 CIG75_RS09050 c37c304441a18cbf153e9746d06ae909 462 PIRSF PIRSF004919 1 460 1.6E-126 T 28-03-2018 IPR025502 TldD CIG75_RS09050 c37c304441a18cbf153e9746d06ae909 462 Pfam PF01523 Putative modulator of DNA gyrase 21 313 4.8E-68 T 28-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 CIG75_RS12340 44bccc23dc3946e0199d69caf2921971 233 Gene3D G3DSA:2.30.30.110 68 196 1.5E-18 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CIG75_RS12340 44bccc23dc3946e0199d69caf2921971 233 SUPERFAMILY SSF50118 71 174 2.62E-13 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CIG75_RS12340 44bccc23dc3946e0199d69caf2921971 233 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 72 174 6.6E-10 T 28-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 CIG75_RS12070 d66e6c9f39d2c2f709ab8c190cd8f809 102 Pfam PF02049 Flagellar hook-basal body complex protein FliE 21 102 1.6E-31 T 28-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 CIG75_RS12070 d66e6c9f39d2c2f709ab8c190cd8f809 102 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 66 82 6.0E-17 T 28-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 CIG75_RS12070 d66e6c9f39d2c2f709ab8c190cd8f809 102 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 87 100 6.0E-17 T 28-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 CIG75_RS12070 d66e6c9f39d2c2f709ab8c190cd8f809 102 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 32 48 6.0E-17 T 28-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 CIG75_RS12070 d66e6c9f39d2c2f709ab8c190cd8f809 102 TIGRFAM TIGR00205 fliE: flagellar hook-basal body complex protein FliE 12 102 7.1E-27 T 28-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 CIG75_RS12070 d66e6c9f39d2c2f709ab8c190cd8f809 102 Hamap MF_00724 Flagellar hook-basal body complex protein FliE [fliE]. 3 102 18.734 T 28-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 CIG75_RS02130 0bebe01dfa24e5ff89c355335798a868 431 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 63 218 7.3E-19 T 28-03-2018 CIG75_RS17305 6180b8f6632c3728c5d8990e541a7a0c 326 Gene3D G3DSA:1.10.600.10 132 305 7.7E-4 T 28-03-2018 IPR008949 Isoprenoid synthase domain CIG75_RS17305 6180b8f6632c3728c5d8990e541a7a0c 326 SUPERFAMILY SSF48576 173 300 1.98E-5 T 28-03-2018 IPR008949 Isoprenoid synthase domain CIG75_RS03970 712df000ff99cf1b5410a24a68cccace 1393 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 683 724 7.8E-6 T 28-03-2018 IPR006530 YD repeat CIG75_RS03970 712df000ff99cf1b5410a24a68cccace 1393 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 725 764 7.4E-4 T 28-03-2018 IPR006530 YD repeat CIG75_RS03970 712df000ff99cf1b5410a24a68cccace 1393 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 836 863 0.0032 T 28-03-2018 IPR006530 YD repeat CIG75_RS03970 712df000ff99cf1b5410a24a68cccace 1393 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 594 625 5.7E-4 T 28-03-2018 IPR006530 YD repeat CIG75_RS03970 712df000ff99cf1b5410a24a68cccace 1393 Pfam PF05593 RHS Repeat 828 865 2.1E-6 T 28-03-2018 IPR031325 RHS repeat CIG75_RS03970 712df000ff99cf1b5410a24a68cccace 1393 Pfam PF05593 RHS Repeat 704 739 1.2E-7 T 28-03-2018 IPR031325 RHS repeat CIG75_RS03970 712df000ff99cf1b5410a24a68cccace 1393 Pfam PF05593 RHS Repeat 746 781 5.1E-7 T 28-03-2018 IPR031325 RHS repeat CIG75_RS03970 712df000ff99cf1b5410a24a68cccace 1393 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1109 1189 1.5E-22 T 28-03-2018 IPR022385 Rhs repeat-associated core GO:0097264 CIG75_RS12750 ab1f74e2014aaf755528fd178121b9cc 1207 Gene3D G3DSA:1.20.120.20 25 690 0.0016 T 28-03-2018 CIG75_RS12750 ab1f74e2014aaf755528fd178121b9cc 1207 TIGRFAM TIGR01760 tape_meas_TP901: phage tail tape measure protein, TP901 family, core region 166 376 1.2E-12 T 28-03-2018 IPR010090 Phage tail tape measure protein CIG75_RS12750 ab1f74e2014aaf755528fd178121b9cc 1207 Gene3D G3DSA:1.20.120.20 986 1181 0.0023 T 28-03-2018 CIG75_RS12750 ab1f74e2014aaf755528fd178121b9cc 1207 Pfam PF10145 Phage-related minor tail protein 187 384 3.8E-15 T 28-03-2018 IPR010090 Phage tail tape measure protein CIG75_RS02200 4f6a7e71d8c0779428dad56915d1f224 83 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 25 34 - T 28-03-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 CIG75_RS02200 4f6a7e71d8c0779428dad56915d1f224 83 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 11 69 5.6E-24 T 28-03-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 CIG75_RS08170 75af3bfd8a14d1c96de9414b73b86a14 339 Pfam PF00482 Type II secretion system (T2SS), protein F 16 133 2.6E-23 T 28-03-2018 IPR018076 Type II secretion system F domain CIG75_RS08170 75af3bfd8a14d1c96de9414b73b86a14 339 Pfam PF00482 Type II secretion system (T2SS), protein F 211 331 6.0E-14 T 28-03-2018 IPR018076 Type II secretion system F domain CIG75_RS08170 75af3bfd8a14d1c96de9414b73b86a14 339 PRINTS PR00812 Bacterial general secretion pathway protein F signature 105 133 1.5E-10 T 28-03-2018 IPR003004 GspF/PilC family CIG75_RS08170 75af3bfd8a14d1c96de9414b73b86a14 339 PRINTS PR00812 Bacterial general secretion pathway protein F signature 320 339 1.5E-10 T 28-03-2018 IPR003004 GspF/PilC family CIG75_RS08170 75af3bfd8a14d1c96de9414b73b86a14 339 PRINTS PR00812 Bacterial general secretion pathway protein F signature 304 318 1.5E-10 T 28-03-2018 IPR003004 GspF/PilC family CIG75_RS12135 d6b1e6eb0553963815394369ef7a2262 161 Pfam PF00881 Nitroreductase family 57 140 1.8E-14 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CIG75_RS12135 d6b1e6eb0553963815394369ef7a2262 161 Gene3D G3DSA:3.40.109.10 2 160 1.5E-35 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CIG75_RS12135 d6b1e6eb0553963815394369ef7a2262 161 SUPERFAMILY SSF55469 1 158 1.03E-36 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CIG75_RS05125 5400cb4c1574c397030fe61539a4d3b5 467 Pfam PF00395 S-layer homology domain 411 455 3.0E-11 T 28-03-2018 IPR001119 S-layer homology domain CIG75_RS05125 5400cb4c1574c397030fe61539a4d3b5 467 Pfam PF00395 S-layer homology domain 349 392 6.4E-10 T 28-03-2018 IPR001119 S-layer homology domain CIG75_RS05125 5400cb4c1574c397030fe61539a4d3b5 467 Pfam PF00395 S-layer homology domain 289 331 3.6E-8 T 28-03-2018 IPR001119 S-layer homology domain CIG75_RS05125 5400cb4c1574c397030fe61539a4d3b5 467 Pfam PF14478 Domain of unknown function (DUF4430) 104 176 9.5E-10 T 28-03-2018 IPR027954 Domain of unknown function DUF4430 Reactome: R-HSA-196741 CIG75_RS00060 9667e60ba7ae9c94fa0109a27a10f6b2 88 Pfam PF10704 Protein of unknown function (DUF2508) 19 76 1.4E-14 T 28-03-2018 IPR019644 Protein of unknown function DUF2508 CIG75_RS06935 b278f3990c380acef5d8098e47678ea3 151 Pfam PF00578 AhpC/TSA family 6 125 4.4E-13 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CIG75_RS06935 b278f3990c380acef5d8098e47678ea3 151 SUPERFAMILY SSF52833 4 144 4.87E-29 T 28-03-2018 IPR012336 Thioredoxin-like fold CIG75_RS06935 b278f3990c380acef5d8098e47678ea3 151 Gene3D G3DSA:3.40.30.10 4 151 2.5E-23 T 28-03-2018 CIG75_RS02095 3398c7df7652be57b4b439cd1ec3a663 378 Gene3D G3DSA:3.40.50.2000 1 165 4.2E-22 T 28-03-2018 CIG75_RS02095 3398c7df7652be57b4b439cd1ec3a663 378 Pfam PF13439 Glycosyltransferase Family 4 16 175 6.2E-22 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CIG75_RS02095 3398c7df7652be57b4b439cd1ec3a663 378 Gene3D G3DSA:3.40.50.2000 166 358 5.2E-45 T 28-03-2018 CIG75_RS02095 3398c7df7652be57b4b439cd1ec3a663 378 SUPERFAMILY SSF53756 10 375 8.07E-81 T 28-03-2018 CIG75_RS02095 3398c7df7652be57b4b439cd1ec3a663 378 Pfam PF00534 Glycosyl transferases group 1 196 351 3.1E-35 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CIG75_RS10550 98b60fb034d26e5fb94b460d35f13858 202 SUPERFAMILY SSF52540 2 22 2.04E-15 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS10550 98b60fb034d26e5fb94b460d35f13858 202 SUPERFAMILY SSF52540 52 201 2.04E-15 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS10550 98b60fb034d26e5fb94b460d35f13858 202 Pfam PF01926 50S ribosome-binding GTPase 4 146 6.2E-8 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CIG75_RS10550 98b60fb034d26e5fb94b460d35f13858 202 Gene3D G3DSA:3.40.50.300 1 202 3.6E-18 T 28-03-2018 CIG75_RS15885 f6a2c044627d1a20c54d41f458a17008 240 SUPERFAMILY SSF53448 1 239 2.7E-36 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CIG75_RS15885 f6a2c044627d1a20c54d41f458a17008 240 Pfam PF12804 MobA-like NTP transferase domain 4 127 8.3E-12 T 28-03-2018 IPR025877 MobA-like NTP transferase CIG75_RS15885 f6a2c044627d1a20c54d41f458a17008 240 Gene3D G3DSA:3.90.550.10 2 240 2.7E-35 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CIG75_RS15380 423c6bba8315a0a586dac81917185843 193 Gene3D G3DSA:3.90.70.10 58 186 7.8E-10 T 28-03-2018 CIG75_RS04860 86f95973652ae317c915587db9d130c1 132 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 2 126 1.5E-41 T 28-03-2018 IPR028973 PhnB-like CIG75_RS04860 86f95973652ae317c915587db9d130c1 132 SUPERFAMILY SSF54593 1 127 8.05E-39 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CIG75_RS04860 86f95973652ae317c915587db9d130c1 132 PIRSF PIRSF021700 1 131 1.1E-42 T 28-03-2018 IPR009725 Predicted 3-demethylubiquinone-9 3-methyltransferase CIG75_RS04860 86f95973652ae317c915587db9d130c1 132 Gene3D G3DSA:3.10.180.10 1 131 7.6E-25 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CIG75_RS15555 87847ab46024c6828f7aa4f089008638 52 Pfam PF13046 Protein of unknown function (DUF3906) 1 48 3.9E-12 T 28-03-2018 IPR024998 Protein of unknown function DUF3906 CIG75_RS09280 1167408aea6de4cd5b3eb0c515b14039 151 Pfam PF04284 Protein of unknown function (DUF441) 5 143 1.8E-45 T 28-03-2018 IPR007382 Uncharacterised protein family UPF0756, transmembrame CIG75_RS09280 1167408aea6de4cd5b3eb0c515b14039 151 ProDom PD021096 MEMBRANE YEAL PRECURSOR SIGNAL PROTEIN TRANSMEMBRANE YTWI HI1074 INTEGRAL SPANNING 38 128 5.0E-19 T 28-03-2018 IPR007382 Uncharacterised protein family UPF0756, transmembrame CIG75_RS09280 1167408aea6de4cd5b3eb0c515b14039 151 Hamap MF_01874 UPF0756 membrane protein YeaL [yeaL]. 1 146 18.968 T 28-03-2018 IPR007382 Uncharacterised protein family UPF0756, transmembrame CIG75_RS18960 01287304549e7f2b4f273afa46a3ade1 138 Pfam PF08890 Phage XkdN-like tail assembly chaperone protein, TAC 3 137 2.8E-46 T 28-03-2018 IPR014986 Clostridium phage phiCD119, XkdN CIG75_RS07740 32d407b441a18c927f1ca31f9a6f8e9b 206 PIRSF PIRSF000170 3 205 2.6E-76 T 28-03-2018 IPR016002 Succinate dehydrogenase cytochrome b558 subunit, Firmicute CIG75_RS07740 32d407b441a18c927f1ca31f9a6f8e9b 206 SUPERFAMILY SSF81343 7 201 1.28E-52 T 28-03-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CIG75_RS07740 32d407b441a18c927f1ca31f9a6f8e9b 206 TIGRFAM TIGR02046 sdhC_b558_fam: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family 9 198 2.9E-33 T 28-03-2018 IPR011138 Succinate dehydrogenase cytochrome b558 subunit CIG75_RS07740 32d407b441a18c927f1ca31f9a6f8e9b 206 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 97 193 5.0E-12 T 28-03-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CIG75_RS07740 32d407b441a18c927f1ca31f9a6f8e9b 206 Gene3D G3DSA:1.20.1300.10 1 204 2.3E-43 T 28-03-2018 CIG75_RS08460 31d926f83ced728e4cab03cbcaf2ee3d 134 Pfam PF02310 B12 binding domain 6 100 2.7E-22 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CIG75_RS08460 31d926f83ced728e4cab03cbcaf2ee3d 134 Gene3D G3DSA:3.40.50.280 1 132 1.7E-38 T 28-03-2018 CIG75_RS08460 31d926f83ced728e4cab03cbcaf2ee3d 134 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 5 132 3.9E-52 T 28-03-2018 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CIG75_RS08460 31d926f83ced728e4cab03cbcaf2ee3d 134 SUPERFAMILY SSF52242 4 128 3.53E-48 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CIG75_RS15875 519af0c4d6db5c4454a3cc7c3ab52906 321 Gene3D G3DSA:3.60.15.10 4 278 2.0E-35 T 28-03-2018 IPR001279 Metallo-beta-lactamase CIG75_RS15875 519af0c4d6db5c4454a3cc7c3ab52906 321 SMART SM00849 28 234 2.1E-27 T 28-03-2018 IPR001279 Metallo-beta-lactamase CIG75_RS15875 519af0c4d6db5c4454a3cc7c3ab52906 321 Pfam PF00753 Metallo-beta-lactamase superfamily 28 226 4.7E-26 T 28-03-2018 IPR001279 Metallo-beta-lactamase CIG75_RS15875 519af0c4d6db5c4454a3cc7c3ab52906 321 SUPERFAMILY SSF56281 14 269 1.22E-49 T 28-03-2018 IPR001279 Metallo-beta-lactamase CIG75_RS03265 cfc77f03ac34700bf144130fffc6d434 215 Pfam PF04012 PspA/IM30 family 3 213 4.5E-42 T 28-03-2018 IPR007157 PspA/IM30 CIG75_RS18840 54143bba27872c36c291f4b90e867160 299 Pfam PF01936 NYN domain 29 169 4.7E-18 T 28-03-2018 IPR021139 NYN domain, limkain-b1-type CIG75_RS18840 54143bba27872c36c291f4b90e867160 299 Gene3D G3DSA:3.40.50.1010 18 186 8.8E-23 T 28-03-2018 IPR029060 PIN domain-like CIG75_RS04035 f9ee862516621676ac9d8f759a458e05 160 Pfam PF06445 GyrI-like small molecule binding domain 2 155 7.9E-24 T 28-03-2018 IPR029442 GyrI-like small molecule binding domain CIG75_RS04035 f9ee862516621676ac9d8f759a458e05 160 SMART SM00871 2 156 1.1E-22 T 28-03-2018 IPR010499 Bacterial transcription activator, effector binding CIG75_RS04035 f9ee862516621676ac9d8f759a458e05 160 Gene3D G3DSA:3.20.80.10 1 160 5.8E-34 T 28-03-2018 IPR011256 Regulatory factor, effector binding domain CIG75_RS04035 f9ee862516621676ac9d8f759a458e05 160 SUPERFAMILY SSF55136 2 157 1.4E-21 T 28-03-2018 CIG75_RS06585 4aa1b989905a7484d129249504c03072 588 Pfam PF08439 Oligopeptidase F 110 165 2.0E-5 T 28-03-2018 IPR013647 Oligopeptidase F, N-terminal domain CIG75_RS06585 4aa1b989905a7484d129249504c03072 588 Pfam PF01432 Peptidase family M3 327 531 1.3E-11 T 28-03-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 CIG75_RS06585 4aa1b989905a7484d129249504c03072 588 SUPERFAMILY SSF55486 47 585 1.1E-74 T 28-03-2018 CIG75_RS05630 9a03ee7a383fd0bd6139b4337736ea4d 167 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 38 66 - T 28-03-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 CIG75_RS05630 9a03ee7a383fd0bd6139b4337736ea4d 167 Gene3D G3DSA:1.10.530.10 12 164 4.0E-40 T 28-03-2018 CIG75_RS05630 9a03ee7a383fd0bd6139b4337736ea4d 167 Pfam PF01464 Transglycosylase SLT domain 20 128 5.3E-33 T 28-03-2018 IPR008258 Transglycosylase SLT domain 1 CIG75_RS05630 9a03ee7a383fd0bd6139b4337736ea4d 167 SUPERFAMILY SSF53955 18 164 4.42E-44 T 28-03-2018 IPR023346 Lysozyme-like domain CIG75_RS08160 6c3099289bd7dca449a50da81d1bd75c 268 SUPERFAMILY SSF56300 42 265 4.85E-33 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CIG75_RS08160 6c3099289bd7dca449a50da81d1bd75c 268 Gene3D G3DSA:3.60.21.10 42 265 8.2E-26 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CIG75_RS08160 6c3099289bd7dca449a50da81d1bd75c 268 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 45 207 1.2E-14 T 28-03-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 CIG75_RS16335 632d59a56b54ddfe41faf28c84e57c50 108 Gene3D G3DSA:2.30.30.340 51 101 3.0E-15 T 28-03-2018 CIG75_RS16335 632d59a56b54ddfe41faf28c84e57c50 108 Pfam PF08838 Protein of unknown function (DUF1811) 4 99 1.2E-26 T 28-03-2018 IPR014938 Protein of unknown function DUF1811 CIG75_RS16335 632d59a56b54ddfe41faf28c84e57c50 108 SUPERFAMILY SSF101697 1 101 1.7E-23 T 28-03-2018 IPR014938 Protein of unknown function DUF1811 CIG75_RS16335 632d59a56b54ddfe41faf28c84e57c50 108 Gene3D G3DSA:1.10.287.880 1 49 1.1E-11 T 28-03-2018 CIG75_RS18765 05ae300a8e9dcc2c7822e884978fa708 167 Gene3D G3DSA:3.40.50.300 1 167 1.6E-23 T 28-03-2018 CIG75_RS18765 05ae300a8e9dcc2c7822e884978fa708 167 Pfam PF03205 Molybdopterin guanine dinucleotide synthesis protein B 4 123 1.3E-32 T 28-03-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 CIG75_RS18765 05ae300a8e9dcc2c7822e884978fa708 167 TIGRFAM TIGR00176 mobB: molybdopterin-guanine dinucleotide biosynthesis protein B 4 157 2.3E-37 T 28-03-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 CIG75_RS18765 05ae300a8e9dcc2c7822e884978fa708 167 SUPERFAMILY SSF52540 1 118 7.91E-16 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS00945 2725e639f88ea1b521960fc06205543c 339 SUPERFAMILY SSF81345 6 336 7.45E-79 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CIG75_RS00945 2725e639f88ea1b521960fc06205543c 339 Pfam PF01032 FecCD transport family 19 336 1.3E-85 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CIG75_RS00945 2725e639f88ea1b521960fc06205543c 339 Gene3D G3DSA:1.10.3470.10 4 339 2.6E-65 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CIG75_RS13530 5be2c48bba3a84c43e64f73e56b6dcef 315 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 9 315 39.27 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CIG75_RS13530 5be2c48bba3a84c43e64f73e56b6dcef 315 Gene3D G3DSA:3.40.50.150 9 315 5.4E-40 T 28-03-2018 CIG75_RS13530 5be2c48bba3a84c43e64f73e56b6dcef 315 SUPERFAMILY SSF81799 118 219 7.32E-36 T 28-03-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CIG75_RS13530 5be2c48bba3a84c43e64f73e56b6dcef 315 SUPERFAMILY SSF53335 8 117 3.02E-45 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CIG75_RS13530 5be2c48bba3a84c43e64f73e56b6dcef 315 SUPERFAMILY SSF53335 219 315 3.02E-45 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CIG75_RS13530 5be2c48bba3a84c43e64f73e56b6dcef 315 PIRSF PIRSF004486 3 315 4.8E-112 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CIG75_RS13530 5be2c48bba3a84c43e64f73e56b6dcef 315 Pfam PF01795 MraW methylase family 7 314 5.0E-128 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CIG75_RS13530 5be2c48bba3a84c43e64f73e56b6dcef 315 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 6 314 8.9E-119 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CIG75_RS14045 66144058fd50fbb734263588925504f7 384 Gene3D G3DSA:3.90.1150.10 245 373 5.6E-36 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CIG75_RS14045 66144058fd50fbb734263588925504f7 384 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 195 214 - T 28-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site CIG75_RS14045 66144058fd50fbb734263588925504f7 384 Gene3D G3DSA:3.40.640.10 14 244 1.1E-57 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CIG75_RS14045 66144058fd50fbb734263588925504f7 384 Pfam PF00266 Aminotransferase class-V 5 367 2.9E-82 T 28-03-2018 IPR000192 Aminotransferase class V domain CIG75_RS14045 66144058fd50fbb734263588925504f7 384 PIRSF PIRSF005572 2 382 1.1E-128 T 28-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CIG75_RS14045 66144058fd50fbb734263588925504f7 384 SUPERFAMILY SSF53383 5 377 2.02E-105 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CIG75_RS07765 6e6474f78174eb1c8455f35c176ef9f6 224 Gene3D G3DSA:3.40.50.1240 31 217 2.5E-24 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CIG75_RS07765 6e6474f78174eb1c8455f35c176ef9f6 224 SMART SM00855 39 182 0.0041 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CIG75_RS07765 6e6474f78174eb1c8455f35c176ef9f6 224 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 40 206 4.3E-24 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CIG75_RS07765 6e6474f78174eb1c8455f35c176ef9f6 224 SUPERFAMILY SSF53254 39 207 5.35E-24 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CIG75_RS07765 6e6474f78174eb1c8455f35c176ef9f6 224 PIRSF PIRSF000709 36 118 11.0 T 28-03-2018 CIG75_RS07765 6e6474f78174eb1c8455f35c176ef9f6 224 PIRSF PIRSF000709 160 216 0.039 T 28-03-2018 CIG75_RS08080 17e8c99f06714a64f814b03e6e2d6861 169 Pfam PF04093 rod shape-determining protein MreD 4 156 1.4E-17 T 28-03-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 CIG75_RS08080 17e8c99f06714a64f814b03e6e2d6861 169 TIGRFAM TIGR03426 shape_MreD: rod shape-determining protein MreD 3 151 1.1E-18 T 28-03-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 CIG75_RS16840 adfd71b744a565383dabd5f2e7954a01 261 Pfam PF12679 ABC-2 family transporter protein 19 259 8.3E-10 T 28-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 CIG75_RS03550 7b8d61eedffaf8c72e484444c2bb9d68 385 Gene3D G3DSA:3.40.1710.10 43 211 6.4E-16 T 28-03-2018 CIG75_RS03550 7b8d61eedffaf8c72e484444c2bb9d68 385 Pfam PF12698 ABC-2 family transporter protein 20 378 3.4E-39 T 28-03-2018 CIG75_RS19205 cbed9b02a4020846e02938fdbc3a24b6 462 SUPERFAMILY SSF48024 22 127 5.75E-6 T 28-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CIG75_RS19205 cbed9b02a4020846e02938fdbc3a24b6 462 Gene3D G3DSA:1.10.860.10 6 159 1.1E-14 T 28-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal CIG75_RS19205 cbed9b02a4020846e02938fdbc3a24b6 462 Gene3D G3DSA:3.40.50.300 180 460 1.7E-41 T 28-03-2018 CIG75_RS19205 cbed9b02a4020846e02938fdbc3a24b6 462 Pfam PF03796 DnaB-like helicase C terminal domain 198 456 9.4E-72 T 28-03-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 CIG75_RS19205 cbed9b02a4020846e02938fdbc3a24b6 462 SUPERFAMILY SSF52540 198 450 1.79E-32 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS18730 f38d129c74c6eb19053adf93949d1b50 338 PIRSF PIRSF002849 2 325 3.8E-139 T 28-03-2018 CIG75_RS18730 f38d129c74c6eb19053adf93949d1b50 338 Gene3D G3DSA:1.10.8.300 227 320 1.1E-33 T 28-03-2018 CIG75_RS18730 f38d129c74c6eb19053adf93949d1b50 338 Gene3D G3DSA:3.40.50.300 5 226 4.3E-28 T 28-03-2018 CIG75_RS18730 f38d129c74c6eb19053adf93949d1b50 338 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 51 181 1.7E-66 T 28-03-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 CIG75_RS18730 f38d129c74c6eb19053adf93949d1b50 338 SUPERFAMILY SSF52540 20 295 3.61E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS03705 481b97b9d1a1d017833f3c704229d3f2 85 Pfam PF06135 Bacterial protein of unknown function (DUF965) 5 80 2.9E-20 T 28-03-2018 IPR009309 Uncharacterised protein family UPF0297 CIG75_RS15700 16cc4d8b3bd256875fe0377f2cf9b776 175 Pfam PF03061 Thioesterase superfamily 30 102 5.1E-17 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CIG75_RS15700 16cc4d8b3bd256875fe0377f2cf9b776 175 Gene3D G3DSA:3.10.129.10 2 164 1.3E-50 T 28-03-2018 CIG75_RS15700 16cc4d8b3bd256875fe0377f2cf9b776 175 SUPERFAMILY SSF54637 7 157 1.83E-47 T 28-03-2018 IPR029069 HotDog domain CIG75_RS12540 579af34b7ed0f284499b0c28f5272458 294 TIGRFAM TIGR00255 TIGR00255: TIGR00255 family protein 1 294 6.3E-78 T 28-03-2018 IPR005229 Conserved hypothetical protein CHP00255 CIG75_RS12540 579af34b7ed0f284499b0c28f5272458 294 Pfam PF08340 Domain of unknown function (DUF1732) 210 294 5.6E-37 T 28-03-2018 IPR013551 Domain of unknown function DUF1732 CIG75_RS12540 579af34b7ed0f284499b0c28f5272458 294 Pfam PF03755 YicC-like family, N-terminal region 2 156 3.8E-38 T 28-03-2018 IPR013527 YicC-like, N-terminal CIG75_RS16785 d6bbd5d93e11f1311a8daa273d92e18e 309 Gene3D G3DSA:3.40.50.1100 13 131 8.8E-26 T 28-03-2018 CIG75_RS16785 d6bbd5d93e11f1311a8daa273d92e18e 309 SUPERFAMILY SSF53686 2 305 4.06E-77 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CIG75_RS16785 d6bbd5d93e11f1311a8daa273d92e18e 309 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 2 288 2.4E-57 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CIG75_RS16785 d6bbd5d93e11f1311a8daa273d92e18e 309 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 25 43 - T 28-03-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 CIG75_RS16785 d6bbd5d93e11f1311a8daa273d92e18e 309 TIGRFAM TIGR03945 PLP_SbnA_fam: 2,3-diaminopropionate biosynthesis protein SbnA 1 303 1.2E-129 T 28-03-2018 IPR023927 2,3-diaminopropionate biosynthesis protein SbnA CIG75_RS16785 d6bbd5d93e11f1311a8daa273d92e18e 309 Gene3D G3DSA:3.40.50.1100 132 308 1.3E-42 T 28-03-2018 CIG75_RS18505 7dd46f0b511d78ab9ddc87f6d4aa2199 340 Pfam PF01370 NAD dependent epimerase/dehydratase family 7 266 2.3E-59 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CIG75_RS18505 7dd46f0b511d78ab9ddc87f6d4aa2199 340 Gene3D G3DSA:3.90.25.10 186 339 1.1E-38 T 28-03-2018 CIG75_RS18505 7dd46f0b511d78ab9ddc87f6d4aa2199 340 PRINTS PR01713 Nucleotide sugar epimerase signature 33 49 5.7E-27 T 28-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 CIG75_RS18505 7dd46f0b511d78ab9ddc87f6d4aa2199 340 PRINTS PR01713 Nucleotide sugar epimerase signature 220 235 5.7E-27 T 28-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 CIG75_RS18505 7dd46f0b511d78ab9ddc87f6d4aa2199 340 PRINTS PR01713 Nucleotide sugar epimerase signature 260 275 5.7E-27 T 28-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 CIG75_RS18505 7dd46f0b511d78ab9ddc87f6d4aa2199 340 PRINTS PR01713 Nucleotide sugar epimerase signature 299 316 5.7E-27 T 28-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 CIG75_RS18505 7dd46f0b511d78ab9ddc87f6d4aa2199 340 Gene3D G3DSA:3.40.50.720 5 185 2.2E-42 T 28-03-2018 CIG75_RS18505 7dd46f0b511d78ab9ddc87f6d4aa2199 340 SUPERFAMILY SSF51735 4 337 3.68E-94 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS03580 600ee5be708470273afb4bb95ecb7af1 126 Gene3D G3DSA:3.10.180.10 4 126 1.2E-20 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CIG75_RS03580 600ee5be708470273afb4bb95ecb7af1 126 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 120 2.6E-7 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CIG75_RS03580 600ee5be708470273afb4bb95ecb7af1 126 SUPERFAMILY SSF54593 8 123 1.29E-20 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CIG75_RS15710 6b53f05cbd12061742878ea84e62ae2b 172 Gene3D G3DSA:2.40.50.120 27 134 1.4E-9 T 28-03-2018 CIG75_RS15710 6b53f05cbd12061742878ea84e62ae2b 172 SUPERFAMILY SSF50242 27 128 5.23E-10 T 28-03-2018 IPR008993 Tissue inhibitor of metalloproteinases-like, OB-fold CIG75_RS17765 51d16a6597850e1c0bed8093415364ba 71 Pfam PF11148 Protein of unknown function (DUF2922) 4 69 4.1E-22 T 28-03-2018 IPR021321 Protein of unknown function DUF2922 CIG75_RS03125 71710499c9cd0587e365c2ecffe118cd 145 Pfam PF08890 Phage XkdN-like tail assembly chaperone protein, TAC 18 144 2.7E-25 T 28-03-2018 IPR014986 Clostridium phage phiCD119, XkdN CIG75_RS15720 ed96b2b6455aa77235114fec15aa7437 187 Gene3D G3DSA:3.40.630.30 3 186 9.8E-32 T 28-03-2018 CIG75_RS15720 ed96b2b6455aa77235114fec15aa7437 187 SUPERFAMILY SSF55729 10 181 9.37E-50 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CIG75_RS15720 ed96b2b6455aa77235114fec15aa7437 187 Pfam PF13302 Acetyltransferase (GNAT) domain 17 157 1.9E-33 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CIG75_RS15185 7e5c6154ac426603499569711e59ddb3 247 SUPERFAMILY SSF51695 7 243 2.35E-82 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CIG75_RS15185 7e5c6154ac426603499569711e59ddb3 247 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 13 236 2.0E-49 T 28-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 CIG75_RS15185 7e5c6154ac426603499569711e59ddb3 247 Gene3D G3DSA:3.20.20.190 1 247 1.3E-80 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CIG75_RS10525 2cf550a0eb5cba4c6587609c390de121 242 Gene3D G3DSA:2.60.120.380 46 186 1.1E-6 T 28-03-2018 CIG75_RS12630 8650a1c56aa8e5004aadc5de4af4577e 269 SUPERFAMILY SSF53474 4 268 1.0E-41 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS12630 8650a1c56aa8e5004aadc5de4af4577e 269 PRINTS PR00111 Alpha/beta hydrolase fold signature 208 222 1.0E-7 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CIG75_RS12630 8650a1c56aa8e5004aadc5de4af4577e 269 PRINTS PR00111 Alpha/beta hydrolase fold signature 93 106 1.0E-7 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CIG75_RS12630 8650a1c56aa8e5004aadc5de4af4577e 269 PRINTS PR00111 Alpha/beta hydrolase fold signature 43 58 1.0E-7 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CIG75_RS12630 8650a1c56aa8e5004aadc5de4af4577e 269 Gene3D G3DSA:3.40.50.1820 2 269 4.1E-46 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS12630 8650a1c56aa8e5004aadc5de4af4577e 269 Pfam PF12146 Serine aminopeptidase, S33 20 254 7.2E-66 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 CIG75_RS18150 e2c9c255643e89c22c101c657c1f1614 332 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 177 4.3E-29 T 28-03-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase CIG75_RS16870 d6bb4f24efb645b0dbfe6fdda49c4974 310 Pfam PF03186 CobD/Cbib protein 3 290 5.1E-108 T 28-03-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 CIG75_RS16870 d6bb4f24efb645b0dbfe6fdda49c4974 310 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 310 106.107 T 28-03-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 CIG75_RS16870 d6bb4f24efb645b0dbfe6fdda49c4974 310 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 3 309 2.2E-89 T 28-03-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 CIG75_RS11095 03d783113e637fc5277e18017646b4b1 532 Gene3D G3DSA:1.10.10.10 269 339 6.9E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS09040 36be6ce98112affa676439a441babb5a 276 Pfam PF03824 High-affinity nickel-transport protein 2 264 8.0E-22 T 28-03-2018 IPR011541 Nickel/cobalt transporter, high-affinity GO:0015099|GO:0016021|GO:0035444|GO:0046872 CIG75_RS16050 824271ada96b3958c7a8407b7e0bb5c6 337 Pfam PF01380 SIS domain 71 111 2.9E-7 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CIG75_RS16050 824271ada96b3958c7a8407b7e0bb5c6 337 Gene3D G3DSA:3.40.50.10490 176 319 2.9E-32 T 28-03-2018 CIG75_RS16050 824271ada96b3958c7a8407b7e0bb5c6 337 TIGRFAM TIGR02128 G6PI_arch: bifunctional phosphoglucose/phosphomannose isomerase 9 335 1.2E-88 T 28-03-2018 IPR011857 Bifunctional phosphoglucose/phosphomannose isomerase GO:0004347|GO:0004476|GO:0005975 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00051+5.3.1.8|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.8+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 CIG75_RS16050 824271ada96b3958c7a8407b7e0bb5c6 337 Pfam PF10432 Bacterial phospho-glucose isomerase C-terminal SIS domain 184 335 7.5E-49 T 28-03-2018 IPR019490 Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase, C-terminal GO:0004347|GO:0004476|GO:0005975 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00051+5.3.1.8|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.8+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 CIG75_RS16050 824271ada96b3958c7a8407b7e0bb5c6 337 Gene3D G3DSA:3.40.50.10490 2 155 1.8E-20 T 28-03-2018 CIG75_RS16050 824271ada96b3958c7a8407b7e0bb5c6 337 SUPERFAMILY SSF53697 40 328 3.4E-70 T 28-03-2018 CIG75_RS01080 153932056136b95687ec86c6a6176034 166 Pfam PF07484 Phage Tail Collar Domain 7 63 5.5E-24 T 28-03-2018 IPR011083 Phage tail collar domain CIG75_RS01080 153932056136b95687ec86c6a6176034 166 Gene3D G3DSA:3.90.1340.10 1 55 9.5E-21 T 28-03-2018 IPR011083 Phage tail collar domain CIG75_RS01080 153932056136b95687ec86c6a6176034 166 SUPERFAMILY SSF88874 1 160 3.79E-43 T 28-03-2018 CIG75_RS01080 153932056136b95687ec86c6a6176034 166 Gene3D G3DSA:4.10.1070.10 56 153 3.1E-6 T 28-03-2018 CIG75_RS04150 0cd27a765eedbfbce6e11e72a1be29c7 107 Pfam PF01476 LysM domain 10 53 3.9E-15 T 28-03-2018 IPR018392 LysM domain CIG75_RS04150 0cd27a765eedbfbce6e11e72a1be29c7 107 SUPERFAMILY SSF54106 9 53 1.11E-11 T 28-03-2018 IPR018392 LysM domain CIG75_RS04150 0cd27a765eedbfbce6e11e72a1be29c7 107 Gene3D G3DSA:1.20.5.170 53 106 3.8E-4 T 28-03-2018 CIG75_RS04150 0cd27a765eedbfbce6e11e72a1be29c7 107 Gene3D G3DSA:3.10.350.10 5 52 4.4E-16 T 28-03-2018 CIG75_RS04150 0cd27a765eedbfbce6e11e72a1be29c7 107 SMART SM00257 9 53 2.1E-14 T 28-03-2018 IPR018392 LysM domain CIG75_RS13925 5803d937fbcfc4da2ad127bd5690f06b 198 TIGRFAM TIGR02830 spore_III_AG: stage III sporulation protein AG 16 198 7.5E-48 T 28-03-2018 IPR014195 Sporulation stage III, protein AG CIG75_RS18750 6c3efec661973c84684516f3f56f245b 253 Pfam PF14014 Protein of unknown function (DUF4230) 95 251 4.7E-24 T 28-03-2018 IPR025324 Protein of unknown function DUF4230 CIG75_RS18635 1caf817a9671c4dc7e71a5a83b5241ba 274 Pfam PF12679 ABC-2 family transporter protein 4 269 7.4E-26 T 28-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 CIG75_RS12095 f52e490e56ec4a75c8e098e6db3e321a 181 Pfam PF00227 Proteasome subunit 7 179 4.7E-26 T 28-03-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-446652|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8941858|Reactome: R-HSA-8951664|Reactome: R-HSA-983168 CIG75_RS12095 f52e490e56ec4a75c8e098e6db3e321a 181 Hamap MF_00248 ATP-dependent protease subunit HslV [hslV]. 8 180 40.77 T 28-03-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 CIG75_RS12095 f52e490e56ec4a75c8e098e6db3e321a 181 PIRSF PIRSF039093 2 181 3.4E-85 T 28-03-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 CIG75_RS12095 f52e490e56ec4a75c8e098e6db3e321a 181 SUPERFAMILY SSF56235 5 180 9.36E-60 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CIG75_RS12095 f52e490e56ec4a75c8e098e6db3e321a 181 Gene3D G3DSA:3.60.20.10 9 181 7.9E-29 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CIG75_RS12095 f52e490e56ec4a75c8e098e6db3e321a 181 TIGRFAM TIGR03692 ATP_dep_HslV: ATP-dependent protease HslVU, peptidase subunit 9 180 9.0E-83 T 28-03-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 CIG75_RS02945 d67b42d260de498147af7556fb2587ca 377 Pfam PF11202 Phosphoribosyl transferase (PRTase) 16 264 8.5E-110 T 28-03-2018 IPR011215 Phosphoribosyl transferase CIG75_RS02945 d67b42d260de498147af7556fb2587ca 377 PIRSF PIRSF020979 6 371 7.2E-95 T 28-03-2018 IPR011215 Phosphoribosyl transferase CIG75_RS02945 d67b42d260de498147af7556fb2587ca 377 Pfam PF15608 PELOTA RNA binding domain 291 371 2.0E-35 T 28-03-2018 IPR028157 PELOTA RNA-binding domain CIG75_RS17895 a1119b4a26cc00708e1471809c5a1cd3 251 Pfam PF09922 Cell wall-active antibiotics response 4TMS YvqF 139 248 3.3E-21 T 28-03-2018 IPR024425 Cell wall-active antibiotics response 4TMS YvqF CIG75_RS02910 af085c62612581cc64742ee37e9a4906 198 Gene3D G3DSA:2.60.60.30 18 195 5.2E-55 T 28-03-2018 CIG75_RS02910 af085c62612581cc64742ee37e9a4906 198 Pfam PF02342 TerD domain 1 197 5.6E-73 T 28-03-2018 IPR003325 TerD domain GO:0006950 CIG75_RS03305 00074971335da8028cb5729b55d86b29 397 Gene3D G3DSA:3.30.470.20 98 387 4.6E-30 T 28-03-2018 CIG75_RS03305 00074971335da8028cb5729b55d86b29 397 SUPERFAMILY SSF56059 88 321 2.65E-25 T 28-03-2018 CIG75_RS04320 2b42b80866aced3c1b0be2be6cfb62f8 225 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 1 216 29.017 T 28-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 CIG75_RS04320 2b42b80866aced3c1b0be2be6cfb62f8 225 Gene3D G3DSA:3.40.50.150 1 215 2.4E-25 T 28-03-2018 CIG75_RS04320 2b42b80866aced3c1b0be2be6cfb62f8 225 SUPERFAMILY SSF53335 31 214 2.13E-25 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CIG75_RS04320 2b42b80866aced3c1b0be2be6cfb62f8 225 Pfam PF02390 Putative methyltransferase 40 211 6.5E-45 T 28-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 CIG75_RS04320 2b42b80866aced3c1b0be2be6cfb62f8 225 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 29 213 5.6E-55 T 28-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 CIG75_RS03340 1dde91e112e6a512b5645de791c7017c 467 PIRSF PIRSF004729 1 459 6.9E-182 T 28-03-2018 IPR006230 Protein MutL CIG75_RS03340 1dde91e112e6a512b5645de791c7017c 467 Pfam PF13941 MutL protein 4 457 1.4E-164 T 28-03-2018 IPR006230 Protein MutL CIG75_RS03340 1dde91e112e6a512b5645de791c7017c 467 TIGRFAM TIGR01319 glmL_fam: conserved hypothetical protein 7 458 2.1E-163 T 28-03-2018 IPR006230 Protein MutL CIG75_RS03340 1dde91e112e6a512b5645de791c7017c 467 Gene3D G3DSA:3.30.420.150 228 414 0.0033 T 28-03-2018 CIG75_RS03340 1dde91e112e6a512b5645de791c7017c 467 SUPERFAMILY SSF53067 4 81 4.07E-5 T 28-03-2018 CIG75_RS03340 1dde91e112e6a512b5645de791c7017c 467 SUPERFAMILY SSF53067 225 272 4.07E-5 T 28-03-2018 CIG75_RS03340 1dde91e112e6a512b5645de791c7017c 467 Gene3D G3DSA:3.20.20.70 36 175 2.8E-5 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CIG75_RS11990 2e7a586050a5833a190277c765991f6b 183 Pfam PF04347 Flagellar biosynthesis protein, FliO 50 163 2.7E-8 T 28-03-2018 IPR022781 Flagellar biosynthesis protein, FliO GO:0016021|GO:0044781 CIG75_RS08900 6a12f0edc07462110bef611b4683da72 270 SUPERFAMILY SSF89550 2 266 4.71E-42 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CIG75_RS08900 6a12f0edc07462110bef611b4683da72 270 Gene3D G3DSA:3.20.20.140 1 266 2.2E-39 T 28-03-2018 CIG75_RS08900 6a12f0edc07462110bef611b4683da72 270 TIGRFAM TIGR01856 hisJ_fam: histidinol phosphate phosphatase, HisJ family 4 244 6.7E-39 T 28-03-2018 IPR010140 Histidinol phosphate phosphatase, HisJ GO:0000105|GO:0004401 KEGG: 00340+3.1.3.15 CIG75_RS11810 ef93637fe80285be0ba456ab42330cef 95 Gene3D G3DSA:3.30.1230.10 1 88 9.9E-29 T 28-03-2018 IPR007393 Domain of unknown function DUF448 CIG75_RS11810 ef93637fe80285be0ba456ab42330cef 95 Pfam PF04296 Protein of unknown function (DUF448) 8 82 4.1E-29 T 28-03-2018 IPR007393 Domain of unknown function DUF448 CIG75_RS11810 ef93637fe80285be0ba456ab42330cef 95 SUPERFAMILY SSF64376 3 86 1.31E-25 T 28-03-2018 IPR007393 Domain of unknown function DUF448 CIG75_RS03015 15264e75eb508d6286949b3b133b0dfe 127 Pfam PF10057 Uncharacterized conserved protein (DUF2294) 6 114 7.6E-36 T 28-03-2018 IPR018745 Domain of unknown function DUF2294 CIG75_RS04020 7fd961a55e4df0c2119af67c181b830a 614 Pfam PF13575 Domain of unknown function (DUF4135) 206 564 4.9E-40 T 28-03-2018 IPR025410 Lantibiotic biosynthesis protein, dehydration domain CIG75_RS06795 ffc676e043142e67c6ab41c05ff737f8 215 SUPERFAMILY SSF109604 1 213 2.08E-72 T 28-03-2018 CIG75_RS06795 ffc676e043142e67c6ab41c05ff737f8 215 Gene3D G3DSA:1.10.3210.10 2 214 4.5E-23 T 28-03-2018 CIG75_RS06795 ffc676e043142e67c6ab41c05ff737f8 215 Pfam PF01966 HD domain 29 126 2.3E-8 T 28-03-2018 IPR006674 HD domain CIG75_RS06795 ffc676e043142e67c6ab41c05ff737f8 215 SMART SM00471 22 136 2.7E-8 T 28-03-2018 IPR003607 HD/PDEase domain CIG75_RS20150 db0c677d801777a37b775922801a0095 290 Pfam PF12679 ABC-2 family transporter protein 4 289 3.0E-12 T 28-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 CIG75_RS11435 656432bac01c041bde2b77ab32dcca28 537 Pfam PF13625 Helicase conserved C-terminal domain 378 491 3.1E-16 T 28-03-2018 IPR032830 Helicase XPB/Ssl2, N-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 CIG75_RS17530 88642db5c2b6f3a54aed12e2eb2ef154 353 Gene3D G3DSA:3.90.820.10 69 129 4.0E-6 T 28-03-2018 CIG75_RS17530 88642db5c2b6f3a54aed12e2eb2ef154 353 Gene3D G3DSA:3.90.820.10 4 61 5.7E-13 T 28-03-2018 CIG75_RS02385 8b13fa313e3b51acf282d662654e008d 115 SUPERFAMILY SSF160214 14 112 2.62E-18 T 28-03-2018 IPR005186 FlaG protein CIG75_RS02385 8b13fa313e3b51acf282d662654e008d 115 Pfam PF03646 FlaG protein 19 112 2.7E-18 T 28-03-2018 IPR005186 FlaG protein CIG75_RS02385 8b13fa313e3b51acf282d662654e008d 115 Gene3D G3DSA:3.30.160.170 15 111 6.9E-18 T 28-03-2018 IPR005186 FlaG protein CIG75_RS18945 fdab2a9fda3d663db638e0d7bd6468d1 198 SMART SM00257 149 198 7.2E-6 T 28-03-2018 IPR018392 LysM domain CIG75_RS18945 fdab2a9fda3d663db638e0d7bd6468d1 198 Pfam PF01476 LysM domain 150 198 8.5E-10 T 28-03-2018 IPR018392 LysM domain CIG75_RS18945 fdab2a9fda3d663db638e0d7bd6468d1 198 Gene3D G3DSA:3.10.350.10 143 198 5.8E-14 T 28-03-2018 CIG75_RS18945 fdab2a9fda3d663db638e0d7bd6468d1 198 SUPERFAMILY SSF54106 147 198 1.83E-6 T 28-03-2018 IPR018392 LysM domain CIG75_RS00285 ded074fe7766b3bad0c85bfdfc7f3f2a 379 PIRSF PIRSF005572 1 379 2.1E-60 T 28-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CIG75_RS00285 ded074fe7766b3bad0c85bfdfc7f3f2a 379 SUPERFAMILY SSF53383 1 376 1.6E-104 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CIG75_RS00285 ded074fe7766b3bad0c85bfdfc7f3f2a 379 Gene3D G3DSA:3.90.1150.10 254 379 6.4E-41 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CIG75_RS00285 ded074fe7766b3bad0c85bfdfc7f3f2a 379 TIGRFAM TIGR01977 am_tr_V_EF2568: cysteine desulfurase family protein 2 376 2.3E-154 T 28-03-2018 IPR010969 Cysteine desulfurase-related, unknown function CIG75_RS00285 ded074fe7766b3bad0c85bfdfc7f3f2a 379 Pfam PF00266 Aminotransferase class-V 2 370 1.6E-97 T 28-03-2018 IPR000192 Aminotransferase class V domain CIG75_RS00285 ded074fe7766b3bad0c85bfdfc7f3f2a 379 Gene3D G3DSA:3.40.640.10 13 253 3.2E-54 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CIG75_RS00285 ded074fe7766b3bad0c85bfdfc7f3f2a 379 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 191 211 - T 28-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site CIG75_RS00940 abb4af6de414f9ab34bddf13bd758d1a 335 Gene3D G3DSA:1.10.3470.10 3 334 1.0E-58 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CIG75_RS00940 abb4af6de414f9ab34bddf13bd758d1a 335 SUPERFAMILY SSF81345 5 326 3.53E-75 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CIG75_RS00940 abb4af6de414f9ab34bddf13bd758d1a 335 Pfam PF01032 FecCD transport family 20 326 4.6E-81 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CIG75_RS11550 092d85c8ad883bfce42b580c967526e6 318 ProSitePatterns PS00869 Renal dipeptidase active site. 110 132 - T 28-03-2018 IPR000180 Membrane dipeptidase, active site GO:0006508|GO:0008235|GO:0008239|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 CIG75_RS11550 092d85c8ad883bfce42b580c967526e6 318 Gene3D G3DSA:3.20.20.140 4 240 7.6E-76 T 28-03-2018 CIG75_RS11550 092d85c8ad883bfce42b580c967526e6 318 Gene3D G3DSA:3.20.20.140 241 318 9.6E-21 T 28-03-2018 CIG75_RS11550 092d85c8ad883bfce42b580c967526e6 318 SUPERFAMILY SSF51556 7 316 3.98E-87 T 28-03-2018 IPR032466 Metal-dependent hydrolase CIG75_RS11550 092d85c8ad883bfce42b580c967526e6 318 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 7 313 4.9E-97 T 28-03-2018 IPR008257 Renal dipeptidase family GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 CIG75_RS00335 b183776d08e78fdaa2b3973f4d8635f0 67 PIRSF PIRSF037263 1 66 1.4E-32 T 28-03-2018 IPR009296 Protein of unknown function DUF951 CIG75_RS00335 b183776d08e78fdaa2b3973f4d8635f0 67 Pfam PF06107 Bacterial protein of unknown function (DUF951) 6 59 7.6E-30 T 28-03-2018 IPR009296 Protein of unknown function DUF951 CIG75_RS05805 6d60f58b243afbb7071d24ca887bb313 372 Pfam PF09376 NurA domain 105 340 7.2E-10 T 28-03-2018 IPR018977 NurA domain CIG75_RS05805 6d60f58b243afbb7071d24ca887bb313 372 SMART SM00933 79 341 1.9E-10 T 28-03-2018 IPR018977 NurA domain CIG75_RS11340 56339ea66cfcb544daef5fb99eb86c2f 556 Gene3D G3DSA:3.50.50.60 2 521 5.6E-31 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS11340 56339ea66cfcb544daef5fb99eb86c2f 556 Pfam PF01593 Flavin containing amine oxidoreductase 18 509 4.6E-21 T 28-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 CIG75_RS11340 56339ea66cfcb544daef5fb99eb86c2f 556 SUPERFAMILY SSF51905 6 326 3.56E-35 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS11340 56339ea66cfcb544daef5fb99eb86c2f 556 SUPERFAMILY SSF51905 468 510 3.56E-35 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS06800 8f93a01f5fe0b7a6794e958bcccfee69 75 ProDom PD002830 NIFU NIFU NITROGEN-FIXING C-TERMINAL FIXATION NITROGEN NIFU-LIKE DOMAIN CLUSTER HESB/YADR/YFHF:NITROGEN-FIXING 12 73 4.0E-20 T 28-03-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 CIG75_RS06800 8f93a01f5fe0b7a6794e958bcccfee69 75 Pfam PF01106 NifU-like domain 8 73 5.6E-29 T 28-03-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 CIG75_RS06800 8f93a01f5fe0b7a6794e958bcccfee69 75 SUPERFAMILY SSF117916 2 75 2.49E-26 T 28-03-2018 IPR034904 Fe-S cluster assembly domain CIG75_RS06800 8f93a01f5fe0b7a6794e958bcccfee69 75 Gene3D G3DSA:3.30.300.130 1 75 1.6E-30 T 28-03-2018 IPR034904 Fe-S cluster assembly domain CIG75_RS11520 fd784ad30432af06c27322c4e59b27fa 424 PIRSF PIRSF006060 1 417 2.8E-67 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CIG75_RS11520 fd784ad30432af06c27322c4e59b27fa 424 Pfam PF13520 Amino acid permease 11 392 8.0E-38 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CIG75_RS02120 205c490090bbc233060a2a5596c96058 1216 Gene3D G3DSA:2.60.40.10 470 583 0.022 T 28-03-2018 IPR013783 Immunoglobulin-like fold CIG75_RS02120 205c490090bbc233060a2a5596c96058 1216 Pfam PF00395 S-layer homology domain 1014 1057 9.7E-7 T 28-03-2018 IPR001119 S-layer homology domain CIG75_RS02120 205c490090bbc233060a2a5596c96058 1216 Pfam PF00395 S-layer homology domain 1092 1124 1.4E-7 T 28-03-2018 IPR001119 S-layer homology domain CIG75_RS16600 fd9c7f8fe3217516d33554b5fab6921c 263 Pfam PF02361 Cobalt transport protein 21 231 3.7E-36 T 28-03-2018 IPR003339 ABC/ECF transporter, transmembrane component CIG75_RS12565 8dfb1b25ae7536295f3f4b60d68f9778 580 Gene3D G3DSA:1.10.8.50 169 241 1.1E-15 T 28-03-2018 CIG75_RS12565 8dfb1b25ae7536295f3f4b60d68f9778 580 Pfam PF05833 Fibronectin-binding protein A N-terminus (FbpA) 4 443 1.6E-149 T 28-03-2018 CIG75_RS12565 8dfb1b25ae7536295f3f4b60d68f9778 580 Gene3D G3DSA:3.40.970.40 245 294 3.1E-14 T 28-03-2018 CIG75_RS12565 8dfb1b25ae7536295f3f4b60d68f9778 580 Gene3D G3DSA:2.30.310.10 1 168 2.5E-50 T 28-03-2018 CIG75_RS12565 8dfb1b25ae7536295f3f4b60d68f9778 580 Pfam PF05670 Domain of unknown function (DUF814) 464 548 6.0E-27 T 28-03-2018 IPR008532 Domain of unknown function DUF814 CIG75_RS10600 bc3c3403304b75f5f336101cf1d45522 144 SUPERFAMILY SSF52540 10 140 2.48E-21 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS10600 bc3c3403304b75f5f336101cf1d45522 144 Gene3D G3DSA:3.40.50.300 1 141 1.5E-19 T 28-03-2018 CIG75_RS10600 bc3c3403304b75f5f336101cf1d45522 144 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 51 141 3.3E-15 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CIG75_RS10600 bc3c3403304b75f5f336101cf1d45522 144 PRINTS PR00819 CbxX/CfqX superfamily signature 50 65 3.9E-35 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CIG75_RS10600 bc3c3403304b75f5f336101cf1d45522 144 PRINTS PR00819 CbxX/CfqX superfamily signature 88 102 3.9E-35 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CIG75_RS10600 bc3c3403304b75f5f336101cf1d45522 144 PRINTS PR00819 CbxX/CfqX superfamily signature 10 24 3.9E-35 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CIG75_RS10600 bc3c3403304b75f5f336101cf1d45522 144 PRINTS PR00819 CbxX/CfqX superfamily signature 102 121 3.9E-35 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CIG75_RS10600 bc3c3403304b75f5f336101cf1d45522 144 PRINTS PR00819 CbxX/CfqX superfamily signature 132 144 3.9E-35 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CIG75_RS05305 6155f7001dc07db0e6efcc77e50b7495 382 Gene3D G3DSA:3.40.1710.10 41 231 2.3E-23 T 28-03-2018 CIG75_RS05305 6155f7001dc07db0e6efcc77e50b7495 382 Pfam PF12698 ABC-2 family transporter protein 20 365 8.2E-25 T 28-03-2018 CIG75_RS11670 3718b11b591493c1acfa251852a27f9a 322 Gene3D G3DSA:1.10.3470.10 2 309 4.9E-47 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CIG75_RS11670 3718b11b591493c1acfa251852a27f9a 322 Pfam PF02653 Branched-chain amino acid transport system / permease component 14 300 3.8E-40 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CIG75_RS11405 824755c0d2b6d2866f859205c16814e6 195 Pfam PF07187 Protein of unknown function (DUF1405) 25 179 2.6E-45 T 28-03-2018 IPR009845 Protein of unknown function DUF1405 CIG75_RS18935 44dffb8398da014637d25ac43b9ba745 89 ProDom PD028957 PBSX RELATED XKDR ELEMENT LIN1285 PHAGE PHAGE-LIKE YQBR 4 88 7.0E-4 T 28-03-2018 IPR022555 Protein of unknown function, DUF2577 CIG75_RS18935 44dffb8398da014637d25ac43b9ba745 89 Pfam PF10844 Protein of unknown function (DUF2577) 64 87 2.5E-5 T 28-03-2018 IPR022555 Protein of unknown function, DUF2577 CIG75_RS18935 44dffb8398da014637d25ac43b9ba745 89 Pfam PF10844 Protein of unknown function (DUF2577) 7 46 6.9E-8 T 28-03-2018 IPR022555 Protein of unknown function, DUF2577 CIG75_RS18970 f3e8dba4531ec3363a39e3ddfd00e6c7 438 Pfam PF17481 Phage tail sheath protein beta-sandwich domain 93 180 1.1E-9 T 28-03-2018 IPR035326 Phage tail sheath protein, beta-sandwich domain CIG75_RS18970 f3e8dba4531ec3363a39e3ddfd00e6c7 438 Pfam PF04984 Phage tail sheath protein subtilisin-like domain 181 329 2.2E-34 T 28-03-2018 IPR035089 Tail sheath protein, subtilisin-like domain CIG75_RS18970 f3e8dba4531ec3363a39e3ddfd00e6c7 438 ProDom PD032508 PHAGE-LIKE PBSX XKDK ELEMENT PHAGE LIN1278 SHEATH YQBL RELATED TAIL 312 438 2.0E-32 T 28-03-2018 IPR020287 Tail sheath protein, C-terminal domain CIG75_RS18970 f3e8dba4531ec3363a39e3ddfd00e6c7 438 Pfam PF17482 Phage tail sheath C-terminal domain 337 438 3.3E-26 T 28-03-2018 IPR020287 Tail sheath protein, C-terminal domain CIG75_RS13190 59148bd9d9a7e46c3adb0603fd1ff85c 153 Hamap MF_01197 Cell division protein SepF [sepF]. 1 136 17.841 T 28-03-2018 IPR023052 Cell division protein SepF GO:0090529 CIG75_RS13190 59148bd9d9a7e46c3adb0603fd1ff85c 153 Pfam PF04472 Cell division protein SepF 57 128 1.1E-29 T 28-03-2018 IPR007561 Cell division protein SepF/SepF-related GO:0090529 CIG75_RS05200 79f5a3662da17ba8a79d4e6a62cebfcd 145 Pfam PF02308 MgtC family 2 117 7.3E-32 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CIG75_RS05200 79f5a3662da17ba8a79d4e6a62cebfcd 145 PRINTS PR01837 MgtC/SapB protein signature 77 101 3.3E-34 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CIG75_RS05200 79f5a3662da17ba8a79d4e6a62cebfcd 145 PRINTS PR01837 MgtC/SapB protein signature 49 71 3.3E-34 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CIG75_RS05200 79f5a3662da17ba8a79d4e6a62cebfcd 145 PRINTS PR01837 MgtC/SapB protein signature 19 37 3.3E-34 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CIG75_RS07175 576ef981148b686e6cec43e26255ddf6 385 Pfam PF01882 Protein of unknown function DUF58 174 256 2.1E-14 T 28-03-2018 IPR002881 Domain of unknown function DUF58 CIG75_RS07175 576ef981148b686e6cec43e26255ddf6 385 Gene3D G3DSA:3.40.50.410 183 351 1.5E-4 T 28-03-2018 IPR002035 von Willebrand factor, type A CIG75_RS18090 7a75264b7b35338d16519613f67d5b81 123 Gene3D G3DSA:3.10.180.10 3 123 4.2E-17 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CIG75_RS18090 7a75264b7b35338d16519613f67d5b81 123 SUPERFAMILY SSF54593 3 120 3.62E-21 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CIG75_RS18090 7a75264b7b35338d16519613f67d5b81 123 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 113 6.6E-6 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CIG75_RS08830 171272c26f0e9d3abf29d3163e1c2606 82 SUPERFAMILY SSF55846 8 74 6.72E-6 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CIG75_RS08830 171272c26f0e9d3abf29d3163e1c2606 82 Gene3D G3DSA:3.40.80.10 5 78 1.5E-4 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CIG75_RS01215 29aaf30845bc067e09a0cadf69d993bd 351 SUPERFAMILY SSF48452 195 314 8.93E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS01215 29aaf30845bc067e09a0cadf69d993bd 351 Gene3D G3DSA:1.25.40.10 189 349 3.4E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS01215 29aaf30845bc067e09a0cadf69d993bd 351 SUPERFAMILY SSF53448 3 94 1.03E-25 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CIG75_RS01215 29aaf30845bc067e09a0cadf69d993bd 351 Gene3D G3DSA:3.90.550.10 3 168 7.8E-27 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CIG75_RS01215 29aaf30845bc067e09a0cadf69d993bd 351 Pfam PF00535 Glycosyl transferase family 2 7 135 1.3E-23 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CIG75_RS07790 398358cb9333c84b40ba14d2269e2117 147 Gene3D G3DSA:1.10.10.10 2 147 5.0E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS07790 398358cb9333c84b40ba14d2269e2117 147 SUPERFAMILY SSF46785 9 146 5.97E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS07790 398358cb9333c84b40ba14d2269e2117 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 55 71 3.3E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CIG75_RS07790 398358cb9333c84b40ba14d2269e2117 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 72 87 3.3E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CIG75_RS07790 398358cb9333c84b40ba14d2269e2117 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 91 107 3.3E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CIG75_RS07790 398358cb9333c84b40ba14d2269e2117 147 Pfam PF01047 MarR family 38 96 2.3E-17 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CIG75_RS07790 398358cb9333c84b40ba14d2269e2117 147 SMART SM00347 31 131 4.7E-23 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CIG75_RS04835 9e42f9c04476cbcc1b025b97e12d9144 202 SUPERFAMILY SSF55486 54 202 7.06E-12 T 28-03-2018 CIG75_RS04835 9e42f9c04476cbcc1b025b97e12d9144 202 Gene3D G3DSA:3.40.390.10 47 202 6.9E-11 T 28-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 CIG75_RS10320 94bff263470edebc96ba1d8721ddf1a3 447 Gene3D G3DSA:1.20.1250.20 234 439 1.0E-15 T 28-03-2018 CIG75_RS10320 94bff263470edebc96ba1d8721ddf1a3 447 Pfam PF07690 Major Facilitator Superfamily 39 393 4.4E-30 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CIG75_RS10320 94bff263470edebc96ba1d8721ddf1a3 447 Gene3D G3DSA:1.20.1250.20 24 220 8.2E-21 T 28-03-2018 CIG75_RS10320 94bff263470edebc96ba1d8721ddf1a3 447 SUPERFAMILY SSF103473 26 433 4.71E-45 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS10735 45e4ba4c793efbd6ccf893a6a070c072 133 Gene3D G3DSA:1.10.10.60 45 108 2.8E-7 T 28-03-2018 CIG75_RS10735 45e4ba4c793efbd6ccf893a6a070c072 133 Gene3D G3DSA:1.10.10.60 7 44 3.2E-17 T 28-03-2018 CIG75_RS10735 45e4ba4c793efbd6ccf893a6a070c072 133 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 1.1E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CIG75_RS10735 45e4ba4c793efbd6ccf893a6a070c072 133 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 1.1E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CIG75_RS10735 45e4ba4c793efbd6ccf893a6a070c072 133 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 58 1.2E-15 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CIG75_RS10735 45e4ba4c793efbd6ccf893a6a070c072 133 SUPERFAMILY SSF46689 5 74 4.94E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CIG75_RS12180 b6064e5de9f84d6d995c1f0fdcb5b10f 163 Gene3D G3DSA:2.40.30.20 65 122 6.9E-5 T 28-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CIG75_RS07140 5f5e1bd5a9977e7b8107fd1c8506ec3b 176 SUPERFAMILY SSF88946 13 96 4.32E-18 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS07140 5f5e1bd5a9977e7b8107fd1c8506ec3b 176 SUPERFAMILY SSF88659 102 169 4.67E-16 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS07140 5f5e1bd5a9977e7b8107fd1c8506ec3b 176 Gene3D G3DSA:1.10.10.10 83 171 2.7E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS07140 5f5e1bd5a9977e7b8107fd1c8506ec3b 176 Pfam PF04542 Sigma-70 region 2 21 86 2.0E-13 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS07140 5f5e1bd5a9977e7b8107fd1c8506ec3b 176 Gene3D G3DSA:1.10.1740.10 8 82 2.9E-17 T 28-03-2018 CIG75_RS07140 5f5e1bd5a9977e7b8107fd1c8506ec3b 176 Pfam PF08281 Sigma-70, region 4 114 166 7.0E-17 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS07140 5f5e1bd5a9977e7b8107fd1c8506ec3b 176 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 15 168 7.9E-33 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CIG75_RS04055 eb46c5962d6add6a1f4b61fd02347a41 148 Gene3D G3DSA:3.40.630.30 1 88 9.4E-11 T 28-03-2018 CIG75_RS04055 eb46c5962d6add6a1f4b61fd02347a41 148 Gene3D G3DSA:3.40.630.30 89 143 1.4E-14 T 28-03-2018 CIG75_RS04055 eb46c5962d6add6a1f4b61fd02347a41 148 SUPERFAMILY SSF55729 3 140 1.23E-25 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CIG75_RS04055 eb46c5962d6add6a1f4b61fd02347a41 148 Pfam PF00583 Acetyltransferase (GNAT) family 39 138 1.7E-16 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CIG75_RS06945 f8ec7de409e9d8359b2d387fe26cff09 282 Pfam PF01976 Protein of unknown function DUF116 131 177 9.9E-6 T 28-03-2018 IPR002829 Protein of unknown function DUF116 CIG75_RS06945 f8ec7de409e9d8359b2d387fe26cff09 282 Pfam PF01976 Protein of unknown function DUF116 182 263 4.6E-19 T 28-03-2018 IPR002829 Protein of unknown function DUF116 CIG75_RS00960 9fbfc25c8e4523677f8990b8ce6d7f71 112 Pfam PF02583 Metal-sensitive transcriptional repressor 32 109 4.9E-29 T 28-03-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 CIG75_RS13465 b75a60ddd21a98d2078e435dcb9c77bc 246 Gene3D G3DSA:1.20.5.340 38 196 1.4E-5 T 28-03-2018 CIG75_RS13465 b75a60ddd21a98d2078e435dcb9c77bc 246 Pfam PF05949 Bacterial protein of unknown function (DUF881) 88 238 2.0E-22 T 28-03-2018 IPR010273 Protein of unknown function DUF881 CIG75_RS12310 3be23a0940116d49f99c1e228977b972 75 SUPERFAMILY SSF54814 5 61 7.19E-7 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CIG75_RS12310 3be23a0940116d49f99c1e228977b972 75 Gene3D G3DSA:3.30.300.20 1 75 7.1E-15 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CIG75_RS12310 3be23a0940116d49f99c1e228977b972 75 Pfam PF13083 KH domain 2 74 1.2E-23 T 28-03-2018 CIG75_RS12310 3be23a0940116d49f99c1e228977b972 75 Hamap MF_00088 UPF0109 protein . 1 75 22.799 T 28-03-2018 IPR020627 Uncharacterised protein family UPF0109 CIG75_RS00460 55f87efa797a0f9fff96e3a41bd4bb67 539 Pfam PF00395 S-layer homology domain 422 462 5.3E-5 T 28-03-2018 IPR001119 S-layer homology domain CIG75_RS00460 55f87efa797a0f9fff96e3a41bd4bb67 539 Pfam PF00395 S-layer homology domain 362 407 5.5E-9 T 28-03-2018 IPR001119 S-layer homology domain CIG75_RS00460 55f87efa797a0f9fff96e3a41bd4bb67 539 Pfam PF09992 Phosphodiester glycosidase 181 349 2.9E-16 T 28-03-2018 IPR018711 Phosphodiester glycosidase CIG75_RS17390 a9c332ef13abba53991d022465ad9bf2 268 Pfam PF00691 OmpA family 145 243 5.0E-18 T 28-03-2018 IPR006665 OmpA-like domain CIG75_RS17390 a9c332ef13abba53991d022465ad9bf2 268 Gene3D G3DSA:3.30.1330.60 81 265 8.2E-41 T 28-03-2018 IPR006665 OmpA-like domain CIG75_RS17390 a9c332ef13abba53991d022465ad9bf2 268 SUPERFAMILY SSF103088 134 249 6.93E-31 T 28-03-2018 IPR006665 OmpA-like domain CIG75_RS17390 a9c332ef13abba53991d022465ad9bf2 268 Pfam PF13677 Membrane MotB of proton-channel complex MotA/MotB 4 58 2.6E-23 T 28-03-2018 IPR025713 Motility protein B, N-terminal domain CIG75_RS00550 9dc423b9eae61cd266885d254d0f2024 293 Pfam PF09648 YycH protein 41 283 3.4E-19 T 28-03-2018 IPR018604 Regulatory protein YycH-like GO:0016021 CIG75_RS13825 48b2b1bd254bc69cf14d5b6caf74c636 143 Gene3D G3DSA:3.30.1450.10 58 139 4.3E-6 T 28-03-2018 CIG75_RS09030 e9dd687490a76532fbc890adfac691b3 212 Pfam PF07293 Protein of unknown function (DUF1450) 12 79 3.1E-7 T 28-03-2018 IPR009910 Protein of unknown function DUF1450 CIG75_RS13045 682b806a7ec1c85dcd85e0dfa8103385 411 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 12 396 2.4E-122 T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CIG75_RS13045 682b806a7ec1c85dcd85e0dfa8103385 411 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 320 340 - T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CIG75_RS13045 682b806a7ec1c85dcd85e0dfa8103385 411 Pfam PF00860 Permease family 17 373 5.1E-98 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CIG75_RS01060 9a8da52fb5b24d9895786be19078ecb6 255 Pfam PF01891 Cobalt uptake substrate-specific transmembrane region 32 239 3.3E-53 T 28-03-2018 IPR002751 Cobalamin (vitamin B12) biosynthesis CbiM family GO:0000041|GO:0016021 CIG75_RS01060 9a8da52fb5b24d9895786be19078ecb6 255 TIGRFAM TIGR00123 cbiM: cobalamin biosynthesis protein CbiM 31 240 3.7E-86 T 28-03-2018 IPR018024 Cobalamin (vitamin B12) biosynthesis protein CbiM GO:0006824|GO:0009236|GO:0016021|GO:0043190 CIG75_RS01060 9a8da52fb5b24d9895786be19078ecb6 255 Hamap MF_01462 Cobalt transport protein CbiM [cbiM]. 31 246 28.722 T 28-03-2018 IPR018024 Cobalamin (vitamin B12) biosynthesis protein CbiM GO:0006824|GO:0009236|GO:0016021|GO:0043190 CIG75_RS12850 8e0aa5164f79e8be6fba2ea98e3e855a 171 Pfam PF08963 Protein of unknown function (DUF1878) 55 163 5.6E-6 T 28-03-2018 IPR015058 Protein of unknown function DUF1878 CIG75_RS12850 8e0aa5164f79e8be6fba2ea98e3e855a 171 Gene3D G3DSA:1.10.3750.10 55 164 6.2E-8 T 28-03-2018 IPR015058 Protein of unknown function DUF1878 CIG75_RS12850 8e0aa5164f79e8be6fba2ea98e3e855a 171 SUPERFAMILY SSF109915 55 162 2.62E-5 T 28-03-2018 IPR015058 Protein of unknown function DUF1878 CIG75_RS15420 84486c54edd1c908a7a81a6326f4d266 153 Pfam PF08741 YwhD family 16 152 6.0E-33 T 28-03-2018 IPR014852 Uncharacterised protein YwhD CIG75_RS01495 482ac18249161e072d147488bb837b06 86 Pfam PF02583 Metal-sensitive transcriptional repressor 6 83 1.0E-25 T 28-03-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 CIG75_RS15840 27dec8ca01e84811f693b1f1af0bacd4 269 SUPERFAMILY SSF51695 10 263 2.2E-75 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CIG75_RS15840 27dec8ca01e84811f693b1f1af0bacd4 269 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 17 257 1.3E-44 T 28-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 CIG75_RS15840 27dec8ca01e84811f693b1f1af0bacd4 269 Gene3D G3DSA:3.20.20.190 3 269 4.7E-71 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CIG75_RS10135 2168354f08690e101aefb6076b152b0f 402 Gene3D G3DSA:3.40.50.2300 211 368 7.5E-23 T 28-03-2018 CIG75_RS10135 2168354f08690e101aefb6076b152b0f 402 Pfam PF13458 Periplasmic binding protein 36 376 5.1E-76 T 28-03-2018 IPR028081 Leucine-binding protein domain CIG75_RS10135 2168354f08690e101aefb6076b152b0f 402 Gene3D G3DSA:3.40.50.2300 21 210 1.8E-32 T 28-03-2018 CIG75_RS10135 2168354f08690e101aefb6076b152b0f 402 SUPERFAMILY SSF53822 36 382 5.59E-90 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CIG75_RS11250 fc682cec1db830629d8a51ab4c5087fe 144 Pfam PF06841 T4-like virus tail tube protein gp19 9 141 5.3E-45 T 28-03-2018 IPR010667 Bacteriophage T4, Gp19, tail tube GO:0005198 CIG75_RS11250 fc682cec1db830629d8a51ab4c5087fe 144 TIGRFAM TIGR02241 TIGR02241: conserved hypothetical phage tail region protein 5 142 1.4E-47 T 28-03-2018 IPR011747 Conserved hypothetical protein CHP02241 CIG75_RS16755 e3690469e73f8511c8447bebff82d84d 384 SUPERFAMILY SSF53383 4 383 7.8E-113 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CIG75_RS16755 e3690469e73f8511c8447bebff82d84d 384 Gene3D G3DSA:3.90.1150.10 296 384 7.1E-24 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CIG75_RS16755 e3690469e73f8511c8447bebff82d84d 384 Gene3D G3DSA:3.40.640.10 43 295 8.6E-60 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CIG75_RS16755 e3690469e73f8511c8447bebff82d84d 384 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 230 243 - T 28-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CIG75_RS16755 e3690469e73f8511c8447bebff82d84d 384 Pfam PF00155 Aminotransferase class I and II 29 377 1.4E-60 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CIG75_RS13975 463262324273433cea7c7bcd5dc994a1 250 Pfam PF14518 Iron-containing redox enzyme 54 216 1.8E-11 T 28-03-2018 IPR028201 PqqC-like protein CIG75_RS13975 463262324273433cea7c7bcd5dc994a1 250 SUPERFAMILY SSF48613 31 244 9.57E-22 T 28-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CIG75_RS13975 463262324273433cea7c7bcd5dc994a1 250 SMART SM01236 88 199 7.9E-8 T 28-03-2018 CIG75_RS13975 463262324273433cea7c7bcd5dc994a1 250 Gene3D G3DSA:1.20.910.10 13 250 9.1E-32 T 28-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CIG75_RS02980 1cb376386c706666a7a8305e6616d5bc 724 Gene3D G3DSA:1.20.1640.10 490 711 6.2E-29 T 28-03-2018 CIG75_RS02980 1cb376386c706666a7a8305e6616d5bc 724 Gene3D G3DSA:1.20.1640.10 136 350 1.6E-27 T 28-03-2018 CIG75_RS02980 1cb376386c706666a7a8305e6616d5bc 724 SUPERFAMILY SSF82866 487 715 4.05E-31 T 28-03-2018 CIG75_RS02980 1cb376386c706666a7a8305e6616d5bc 724 SUPERFAMILY SSF82866 129 353 2.35E-27 T 28-03-2018 CIG75_RS02980 1cb376386c706666a7a8305e6616d5bc 724 Pfam PF03176 MMPL family 412 717 8.0E-56 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CIG75_RS02980 1cb376386c706666a7a8305e6616d5bc 724 Pfam PF03176 MMPL family 50 381 1.2E-51 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CIG75_RS13525 2a98ddee07139e07dbae47a23de57ac1 130 Pfam PF04999 Cell division protein FtsL 52 125 4.3E-7 T 28-03-2018 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 CIG75_RS11215 3bee6acfc5d721417a07e918319f7f2a 187 SUPERFAMILY SSF69255 17 95 2.54E-19 T 28-03-2018 CIG75_RS11215 3bee6acfc5d721417a07e918319f7f2a 187 Gene3D G3DSA:2.40.50.260 12 122 2.7E-28 T 28-03-2018 CIG75_RS11215 3bee6acfc5d721417a07e918319f7f2a 187 SUPERFAMILY SSF69349 88 162 9.42E-5 T 28-03-2018 CIG75_RS19035 c06ec3f3beb03862c4106abe9cc90329 482 TIGRFAM TIGR01538 portal_SPP1: phage portal protein, SPP1 family 38 468 2.3E-54 T 28-03-2018 IPR006428 Portal protein, SPP1-type CIG75_RS19035 c06ec3f3beb03862c4106abe9cc90329 482 Pfam PF05133 Phage portal protein, SPP1 Gp6-like 34 471 5.5E-88 T 28-03-2018 IPR021145 Portal protein CIG75_RS10835 606f4254c8d15855c4f3a1bff5fe3e3b 264 Pfam PF04445 Putative SAM-dependent methyltransferase 82 232 1.0E-16 T 28-03-2018 IPR007536 Ribosomal RNA small subunit methyltransferase J GO:0008990|GO:0031167 CIG75_RS10835 606f4254c8d15855c4f3a1bff5fe3e3b 264 Gene3D G3DSA:3.40.50.150 70 262 2.7E-21 T 28-03-2018 CIG75_RS10835 606f4254c8d15855c4f3a1bff5fe3e3b 264 SUPERFAMILY SSF53335 8 246 2.53E-54 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CIG75_RS04610 afd73e3504d3912bf4e74ba73f162208 499 SUPERFAMILY SSF52317 21 137 5.72E-11 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CIG75_RS04610 afd73e3504d3912bf4e74ba73f162208 499 SUPERFAMILY SSF52317 175 307 5.72E-11 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CIG75_RS04610 afd73e3504d3912bf4e74ba73f162208 499 Gene3D G3DSA:3.40.50.880 13 326 2.9E-39 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CIG75_RS16370 f3f77b779aa23487303e8445103462d5 331 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 99 319 1.4E-58 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CIG75_RS16370 f3f77b779aa23487303e8445103462d5 331 SUPERFAMILY SSF56529 95 320 5.63E-71 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CIG75_RS16370 f3f77b779aa23487303e8445103462d5 331 Gene3D G3DSA:3.90.850.10 54 328 1.2E-69 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CIG75_RS04045 fee9bbb3dfcc166ac176976e3a324cde 207 SUPERFAMILY SSF55811 23 198 1.3E-32 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CIG75_RS04045 fee9bbb3dfcc166ac176976e3a324cde 207 Pfam PF12535 Hydrolase of X-linked nucleoside diphosphate N terminal 4 59 4.8E-27 T 28-03-2018 CIG75_RS04045 fee9bbb3dfcc166ac176976e3a324cde 207 Pfam PF00293 NUDIX domain 69 180 8.2E-16 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CIG75_RS04045 fee9bbb3dfcc166ac176976e3a324cde 207 Gene3D G3DSA:3.90.79.10 58 203 5.3E-26 T 28-03-2018 CIG75_RS06030 3fd2283cb1262270e8029acdb546413e 172 Pfam PF02674 Colicin V production protein 3 159 3.1E-29 T 28-03-2018 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 CIG75_RS05440 a2f81cd4dd9caa129b1dbd696af700d6 329 Pfam PF03787 RAMP superfamily 37 238 2.4E-7 T 28-03-2018 IPR005537 CRISPR type III-associated RAMP protein CIG75_RS04415 ece522c0de8b743b25a3585bbc2805a0 355 Gene3D G3DSA:1.10.3210.10 29 298 1.7E-28 T 28-03-2018 CIG75_RS04415 ece522c0de8b743b25a3585bbc2805a0 355 SMART SM00471 123 259 1.8E-6 T 28-03-2018 IPR003607 HD/PDEase domain CIG75_RS04415 ece522c0de8b743b25a3585bbc2805a0 355 SUPERFAMILY SSF109604 120 285 2.09E-21 T 28-03-2018 CIG75_RS04415 ece522c0de8b743b25a3585bbc2805a0 355 Pfam PF01966 HD domain 128 249 1.1E-11 T 28-03-2018 IPR006674 HD domain CIG75_RS06740 b983532f23929aceca2d37c399e6f323 422 Gene3D G3DSA:1.20.1250.20 223 422 3.5E-14 T 28-03-2018 CIG75_RS06740 b983532f23929aceca2d37c399e6f323 422 Pfam PF07690 Major Facilitator Superfamily 48 372 7.9E-23 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CIG75_RS06740 b983532f23929aceca2d37c399e6f323 422 Gene3D G3DSA:1.20.1250.20 13 208 1.1E-19 T 28-03-2018 CIG75_RS06740 b983532f23929aceca2d37c399e6f323 422 SUPERFAMILY SSF103473 23 408 2.22E-40 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS12055 47b95b678919663351a31b88e6b90cfe 256 SUPERFAMILY SSF160527 160 247 1.02E-5 T 28-03-2018 CIG75_RS12055 47b95b678919663351a31b88e6b90cfe 256 Pfam PF02108 Flagellar assembly protein FliH 129 243 3.4E-23 T 28-03-2018 IPR018035 Flagellar assembly protein FliH/Type III secretion system HrpE CIG75_RS18710 46945ec7d890ae1efdcdc958891b742f 466 Pfam PF00860 Permease family 17 418 3.6E-36 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CIG75_RS15310 11c6712e7cbca106629b60d56b9e2763 269 TIGRFAM TIGR01097 PhnE: phosphonate ABC transporter, permease protein PhnE 19 268 1.1E-89 T 28-03-2018 IPR005769 ABC transporter, permease PhnE/PtxC GO:0005887|GO:0015604|GO:0015716 CIG75_RS15310 11c6712e7cbca106629b60d56b9e2763 269 Gene3D G3DSA:1.10.3720.10 19 269 2.8E-32 T 28-03-2018 CIG75_RS15310 11c6712e7cbca106629b60d56b9e2763 269 SUPERFAMILY SSF161098 72 259 1.83E-38 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CIG75_RS15310 11c6712e7cbca106629b60d56b9e2763 269 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 96 261 4.8E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CIG75_RS05480 bbbc2727073b844ece1eda1650acbfdc 373 Pfam PF14398 YheC/D like ATP-grasp 115 358 4.4E-58 T 28-03-2018 IPR026838 Endospore coat-associated protein YheC/D CIG75_RS05480 bbbc2727073b844ece1eda1650acbfdc 373 SUPERFAMILY SSF56059 141 351 5.13E-16 T 28-03-2018 CIG75_RS05480 bbbc2727073b844ece1eda1650acbfdc 373 Gene3D G3DSA:3.30.470.20 220 356 8.1E-12 T 28-03-2018 CIG75_RS05480 bbbc2727073b844ece1eda1650acbfdc 373 Gene3D G3DSA:3.30.1490.20 145 219 3.2E-9 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CIG75_RS06955 def999728b7c7bd1b6a56e90c436b64b 354 Pfam PF01594 AI-2E family transporter 36 347 1.8E-78 T 28-03-2018 IPR002549 Transmembrane protein TqsA-like CIG75_RS10360 045cab7ce177a2df2362fdc1bceec1e3 229 Pfam PF03301 Tryptophan 2,3-dioxygenase 6 115 5.7E-12 T 28-03-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 CIG75_RS10360 045cab7ce177a2df2362fdc1bceec1e3 229 SUPERFAMILY SSF140959 7 212 1.7E-45 T 28-03-2018 CIG75_RS02675 736c8c7d2fac72009af20071bef57e07 111 Pfam PF12788 YmaF family 15 69 6.6E-9 T 28-03-2018 IPR024307 YmaF CIG75_RS10555 777264f9489d7cd43ddef6398a155205 197 SUPERFAMILY SSF52540 29 191 3.49E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS10555 777264f9489d7cd43ddef6398a155205 197 Pfam PF00005 ABC transporter 36 122 1.4E-6 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS10555 777264f9489d7cd43ddef6398a155205 197 Gene3D G3DSA:3.40.50.300 7 195 9.0E-36 T 28-03-2018 CIG75_RS04305 931f824ca45a792669bd13ab028d1681 542 SUPERFAMILY SSF51905 29 330 4.84E-60 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS04305 931f824ca45a792669bd13ab028d1681 542 SUPERFAMILY SSF51905 477 537 4.84E-60 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS04305 931f824ca45a792669bd13ab028d1681 542 Pfam PF00732 GMC oxidoreductase 32 303 5.8E-17 T 28-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CIG75_RS04305 931f824ca45a792669bd13ab028d1681 542 SUPERFAMILY SSF54373 312 465 1.61E-14 T 28-03-2018 CIG75_RS04305 931f824ca45a792669bd13ab028d1681 542 Pfam PF05199 GMC oxidoreductase 413 528 4.4E-25 T 28-03-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 CIG75_RS04305 931f824ca45a792669bd13ab028d1681 542 Gene3D G3DSA:3.50.50.60 20 542 5.3E-62 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS07965 78e5ca05ade3d6f2f8c189085fb5019a 379 Gene3D G3DSA:3.40.50.2000 151 366 1.0E-46 T 28-03-2018 CIG75_RS07965 78e5ca05ade3d6f2f8c189085fb5019a 379 Pfam PF13439 Glycosyltransferase Family 4 17 167 2.0E-9 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CIG75_RS07965 78e5ca05ade3d6f2f8c189085fb5019a 379 SUPERFAMILY SSF53756 9 371 7.63E-75 T 28-03-2018 CIG75_RS07965 78e5ca05ade3d6f2f8c189085fb5019a 379 Pfam PF00534 Glycosyl transferases group 1 182 347 1.0E-35 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CIG75_RS01965 08d8bb87bba2ee4581fcafc66dafdd06 185 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 66 183 1.7E-33 T 28-03-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CIG75_RS01965 08d8bb87bba2ee4581fcafc66dafdd06 185 ProSitePatterns PS00542 Respiratory chain NADH dehydrogenase 30 Kd subunit signature. 146 167 - T 28-03-2018 IPR020396 NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CIG75_RS01965 08d8bb87bba2ee4581fcafc66dafdd06 185 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 132 185 2.0E-12 T 28-03-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CIG75_RS01965 08d8bb87bba2ee4581fcafc66dafdd06 185 SUPERFAMILY SSF143243 44 183 5.89E-35 T 28-03-2018 CIG75_RS12590 df6c57b435cf214bb467e9a7a417efb1 274 Gene3D G3DSA:3.30.470.20 110 242 8.9E-12 T 28-03-2018 CIG75_RS12590 df6c57b435cf214bb467e9a7a417efb1 274 SUPERFAMILY SSF56059 36 234 4.86E-13 T 28-03-2018 CIG75_RS12590 df6c57b435cf214bb467e9a7a417efb1 274 Gene3D G3DSA:3.30.1490.20 43 109 4.4E-9 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CIG75_RS12590 df6c57b435cf214bb467e9a7a417efb1 274 Pfam PF14398 YheC/D like ATP-grasp 20 250 2.2E-54 T 28-03-2018 IPR026838 Endospore coat-associated protein YheC/D CIG75_RS18920 4c72ce92a197fd6aececf92ca0448a81 359 Pfam PF04865 Baseplate J-like protein 62 318 2.1E-60 T 28-03-2018 IPR006949 Baseplate protein J-like CIG75_RS07670 cc1e8c7c6af6e233786cb905bc75fec4 210 Gene3D G3DSA:3.40.630.30 1 210 9.6E-44 T 28-03-2018 CIG75_RS07670 cc1e8c7c6af6e233786cb905bc75fec4 210 PIRSF PIRSF021278 2 210 1.1E-83 T 28-03-2018 IPR024699 Acetoin utilization protein AcuA GO:0019152|GO:0045150 CIG75_RS07670 cc1e8c7c6af6e233786cb905bc75fec4 210 SUPERFAMILY SSF55729 35 120 1.7E-5 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CIG75_RS00395 5f974050310525608fe666665abc3599 143 Pfam PF03795 YCII-related domain 1 117 1.9E-20 T 28-03-2018 IPR005545 YCII-related CIG75_RS00395 5f974050310525608fe666665abc3599 143 SUPERFAMILY SSF54909 1 118 1.63E-30 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CIG75_RS00395 5f974050310525608fe666665abc3599 143 Gene3D G3DSA:3.30.70.1060 1 121 6.0E-36 T 28-03-2018 CIG75_RS09710 323b740c23a62fa13d4c307aa5b92dc3 431 Pfam PF13492 GAF domain 171 295 6.7E-12 T 28-03-2018 IPR003018 GAF domain GO:0005515 CIG75_RS09710 323b740c23a62fa13d4c307aa5b92dc3 431 Gene3D G3DSA:3.30.450.40 120 304 3.6E-16 T 28-03-2018 IPR029016 GAF domain-like CIG75_RS09710 323b740c23a62fa13d4c307aa5b92dc3 431 SMART SM00065 171 303 0.004 T 28-03-2018 IPR003018 GAF domain GO:0005515 CIG75_RS09710 323b740c23a62fa13d4c307aa5b92dc3 431 SUPERFAMILY SSF55781 172 303 4.36E-12 T 28-03-2018 IPR029016 GAF domain-like CIG75_RS02180 439ac9352eec7a2289b02dfd8c6dc8e6 367 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 134 280 3.6E-40 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CIG75_RS02180 439ac9352eec7a2289b02dfd8c6dc8e6 367 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 135 280 6.3E-42 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CIG75_RS00420 f7e6da596f86d92b0ad0cfeca407b9de 198 Gene3D G3DSA:1.10.287.70 41 137 4.1E-6 T 28-03-2018 CIG75_RS00420 f7e6da596f86d92b0ad0cfeca407b9de 198 Pfam PF10067 Predicted membrane protein (DUF2306) 51 192 5.9E-32 T 28-03-2018 IPR018750 Protein of unknown function DUF2306, membrane CIG75_RS01400 2b97b01f1a08fe94f531f09f2b088353 463 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 6 353 6.2E-51 T 28-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 CIG75_RS01400 2b97b01f1a08fe94f531f09f2b088353 463 Pfam PF03845 Spore germination protein 6 304 1.1E-40 T 28-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 CIG75_RS11485 03bf64ba67573a9ebf46df5e19df9163 383 Pfam PF14395 Phage phiEco32-like COOH.NH2 ligase-type 2 113 365 1.0E-96 T 28-03-2018 IPR025681 Phage phiEco32-like COOH-NH2 ligase-type 2 CIG75_RS07310 5d24fb1d84c177a8e843fa464c5b2758 243 Gene3D G3DSA:3.40.1800.10 145 234 4.5E-8 T 28-03-2018 CIG75_RS07310 5d24fb1d84c177a8e843fa464c5b2758 243 Pfam PF01844 HNH endonuclease 168 223 9.9E-10 T 28-03-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 CIG75_RS20220 ce4e29cc2cfba639042e954279aecdea 227 Pfam PF09578 Spore cortex protein YabQ (Spore_YabQ) 11 87 1.6E-15 T 28-03-2018 IPR019074 Spore cortex biosynthesis protein, YabQ-like CIG75_RS20220 ce4e29cc2cfba639042e954279aecdea 227 TIGRFAM TIGR02893 spore_yabQ: spore cortex biosynthesis protein YabQ 2 129 1.4E-23 T 28-03-2018 IPR014242 Spore cortex biosynthesis protein, YabQ CIG75_RS07600 8b3274342af7e3f4666891c4ce5c9290 215 Pfam PF07987 Domain of unkown function (DUF1775) 26 149 2.8E-21 T 28-03-2018 IPR012533 YcnI-like CIG75_RS20215 989545088766a5ca2ee9b9079139e6db 121 Gene3D G3DSA:1.20.5.1000 58 104 5.1E-4 T 28-03-2018 CIG75_RS20215 989545088766a5ca2ee9b9079139e6db 121 Pfam PF04977 Septum formation initiator 45 119 1.0E-15 T 28-03-2018 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 CIG75_RS02110 c519d4e55384620da156eae1306cd131 801 SUPERFAMILY SSF49265 354 564 3.55E-9 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CIG75_RS02110 c519d4e55384620da156eae1306cd131 801 Gene3D G3DSA:2.60.40.10 350 459 1.0E-13 T 28-03-2018 IPR013783 Immunoglobulin-like fold CIG75_RS02110 c519d4e55384620da156eae1306cd131 801 Gene3D G3DSA:2.60.40.10 470 564 1.4E-7 T 28-03-2018 IPR013783 Immunoglobulin-like fold CIG75_RS02110 c519d4e55384620da156eae1306cd131 801 Gene3D G3DSA:2.60.40.10 577 694 0.0084 T 28-03-2018 IPR013783 Immunoglobulin-like fold CIG75_RS11265 2fcc5b3f6e796c12716df1e2568bdbb8 188 Pfam PF14065 Protein of unknown function (DUF4255) 9 180 7.6E-25 T 28-03-2018 IPR025351 Protein of unknown function DUF4255 CIG75_RS09840 f7f9cdd71d7f0f863c7ec9770925ccac 162 Pfam PF07849 Protein of unknown function (DUF1641) 122 156 1.7E-9 T 28-03-2018 IPR012440 Protein of unknown function DUF1641 CIG75_RS13460 3d15ec62a1a16fc5fbbc4ab1dc8080c4 119 PIRSF PIRSF018579 2 114 1.4E-46 T 28-03-2018 IPR009709 Protein of unknown function DUF1290 CIG75_RS13460 3d15ec62a1a16fc5fbbc4ab1dc8080c4 119 Pfam PF06947 Protein of unknown function (DUF1290) 23 107 1.3E-38 T 28-03-2018 IPR009709 Protein of unknown function DUF1290 CIG75_RS02605 6b3a73ef3e69392ab07c4d90a36d64a5 270 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 205 232 1.3E-5 T 28-03-2018 IPR001451 Hexapeptide repeat CIG75_RS02605 6b3a73ef3e69392ab07c4d90a36d64a5 270 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 103 135 1.5E-4 T 28-03-2018 IPR001451 Hexapeptide repeat CIG75_RS02605 6b3a73ef3e69392ab07c4d90a36d64a5 270 SUPERFAMILY SSF51161 65 171 1.43E-27 T 28-03-2018 IPR011004 Trimeric LpxA-like CIG75_RS02605 6b3a73ef3e69392ab07c4d90a36d64a5 270 SUPERFAMILY SSF51161 203 230 1.43E-27 T 28-03-2018 IPR011004 Trimeric LpxA-like CIG75_RS02605 6b3a73ef3e69392ab07c4d90a36d64a5 270 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 111 139 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CIG75_RS02605 6b3a73ef3e69392ab07c4d90a36d64a5 270 Gene3D G3DSA:2.160.10.10 53 239 3.1E-29 T 28-03-2018 CIG75_RS02930 dbb45308188bbdcbda590b844d69a85d 243 Pfam PF03741 Integral membrane protein TerC family 39 207 4.2E-53 T 28-03-2018 IPR005496 Integral membrane protein TerC GO:0016021 CIG75_RS02930 dbb45308188bbdcbda590b844d69a85d 243 TIGRFAM TIGR03716 R_switched_YkoY: integral membrane protein, YkoY family 36 236 6.5E-76 T 28-03-2018 IPR022493 Integral membrane YkoY CIG75_RS10535 d9167a6819b7a0bcdc1d68fa6948da5f 80 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 15 67 5.0E-7 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CIG75_RS10535 d9167a6819b7a0bcdc1d68fa6948da5f 80 Gene3D G3DSA:3.40.47.10 9 72 2.7E-6 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CIG75_RS12010 ce24241c58cbba95e902ad6f1d099c60 146 Pfam PF03748 Flagellar basal body-associated protein FliL 55 146 6.9E-14 T 28-03-2018 IPR005503 Flagellar basal body-associated protein FliL GO:0006935|GO:0009425|GO:0071973 CIG75_RS20335 518dc38bf93f84c21422deb583ea68f3 60 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 11 55 2.0E-6 T 28-03-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 CIG75_RS20335 518dc38bf93f84c21422deb583ea68f3 60 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 14 23 - T 28-03-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 CIG75_RS12725 7e2264dcd30972038d80d97183c9bb8d 361 Pfam PF04865 Baseplate J-like protein 69 322 2.0E-43 T 28-03-2018 IPR006949 Baseplate protein J-like CIG75_RS02090 34695cb4c7b9129d7f85506393059c3c 449 Pfam PF04932 O-Antigen ligase 237 372 1.4E-19 T 28-03-2018 IPR007016 O-antigen ligase-related CIG75_RS10155 ae40bf2926831eee5e0261fa8e24bc12 317 Gene3D G3DSA:1.10.3470.10 10 304 2.3E-35 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CIG75_RS10155 ae40bf2926831eee5e0261fa8e24bc12 317 Pfam PF02653 Branched-chain amino acid transport system / permease component 31 296 7.9E-41 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CIG75_RS09395 183970d4113b868e881c676c99659e6b 161 Pfam PF11385 Protein of unknown function (DUF3189) 2 147 8.0E-51 T 28-03-2018 IPR021525 Protein of unknown function DUF3189 CIG75_RS19260 77943056166be7e69df17b84facf2774 138 SMART SM00530 14 69 3.7E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS19260 77943056166be7e69df17b84facf2774 138 SUPERFAMILY SSF47413 9 75 2.01E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CIG75_RS19260 77943056166be7e69df17b84facf2774 138 Gene3D G3DSA:1.10.260.40 3 138 2.2E-20 T 28-03-2018 CIG75_RS19260 77943056166be7e69df17b84facf2774 138 Pfam PF12844 Helix-turn-helix domain 12 74 2.8E-16 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CIG75_RS11675 c06444f1af694e1c4cf729706786ce94 354 Gene3D G3DSA:1.10.3470.10 3 354 9.8E-49 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CIG75_RS11675 c06444f1af694e1c4cf729706786ce94 354 Pfam PF02653 Branched-chain amino acid transport system / permease component 54 332 7.6E-41 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CIG75_RS14705 3f0c5777886deed861338edd2cca0b89 52 Pfam PF14006 YqzL-like protein 6 33 3.3E-12 T 28-03-2018 IPR025617 YqzL-like protein CIG75_RS15125 60250d943ea2fe339ebfd50d81fbda66 144 Gene3D G3DSA:1.20.120.580 3 143 4.9E-24 T 28-03-2018 IPR008201 Protein of unknown function DUF86 CIG75_RS15125 60250d943ea2fe339ebfd50d81fbda66 144 Pfam PF01934 Protein of unknown function DUF86 29 131 2.1E-23 T 28-03-2018 IPR008201 Protein of unknown function DUF86 CIG75_RS08870 094cf0bc0cd550f802908a3bedb0737f 192 Pfam PF09580 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) 17 188 3.5E-21 T 28-03-2018 IPR019076 Sporulation lipoprotein YhcN/YlaJ-like CIG75_RS18010 76c706362af98872a3405ae4e0f3a55b 96 Gene3D G3DSA:2.60.300.12 1 94 1.2E-12 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CIG75_RS18010 76c706362af98872a3405ae4e0f3a55b 96 SUPERFAMILY SSF89360 3 90 1.65E-10 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CIG75_RS03155 4abaec6810ffe7a30c3699e0a5336258 384 Pfam PF04865 Baseplate J-like protein 73 338 1.6E-60 T 28-03-2018 IPR006949 Baseplate protein J-like CIG75_RS20425 4a4e85189c244afe71517846fd0289fa 159 Pfam PF04308 Ribonuclease H-like 15 158 7.1E-51 T 28-03-2018 IPR007405 Bacteriophage KVP40, Orf299 CIG75_RS00805 1a6acbc249f532c134c1935168c4cb4d 160 Pfam PF11188 Protein of unknown function (DUF2975) 31 160 2.5E-38 T 28-03-2018 IPR021354 Protein of unknown function DUF2975 CIG75_RS13585 1608d536da6a6d0ce2e23e40fc420243 71 SUPERFAMILY SSF51230 3 70 1.13E-22 T 28-03-2018 IPR011053 Single hybrid motif CIG75_RS13585 1608d536da6a6d0ce2e23e40fc420243 71 Pfam PF00364 Biotin-requiring enzyme 3 68 7.4E-19 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CIG75_RS13585 1608d536da6a6d0ce2e23e40fc420243 71 Gene3D G3DSA:2.40.50.100 1 71 1.3E-20 T 28-03-2018 CIG75_RS07945 ccfffa5f0586aead2c69d7b2818236ef 135 Pfam PF04134 Protein of unknown function, DUF393 9 116 1.3E-18 T 28-03-2018 IPR007263 Protein of unknown function DUF393 CIG75_RS14940 ba1073c8d8b602883c1999e293f50392 235 Gene3D G3DSA:1.20.1660.10 6 104 4.1E-4 T 28-03-2018 CIG75_RS14940 ba1073c8d8b602883c1999e293f50392 235 Pfam PF08713 DNA alkylation repair enzyme 6 216 7.7E-21 T 28-03-2018 IPR014825 DNA alkylation repair enzyme CIG75_RS14940 ba1073c8d8b602883c1999e293f50392 235 SUPERFAMILY SSF48371 1 235 9.5E-63 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 CIG75_RS13475 1d9aac92b0da2cae474d3ac7ccfc43ab 263 Pfam PF08478 POTRA domain, FtsQ-type 52 119 3.1E-13 T 28-03-2018 IPR013685 POTRA domain, FtsQ-type CIG75_RS13475 1d9aac92b0da2cae474d3ac7ccfc43ab 263 Pfam PF03799 Cell division protein FtsQ 133 244 3.2E-9 T 28-03-2018 IPR005548 Cell division protein FtsQ/DivIB CIG75_RS09740 b316ef917654f0462cb962e232a6eba8 91 ProDom PD058324 UPF0349 LMO2392 BLI03401/BL03152 SA0800 SAR0901 LIN2491 SERP0525 GK2958 BT9727_4649 BC4937 16 86 2.0E-4 T 28-03-2018 CIG75_RS09740 b316ef917654f0462cb962e232a6eba8 91 Pfam PF07293 Protein of unknown function (DUF1450) 16 87 1.9E-12 T 28-03-2018 IPR009910 Protein of unknown function DUF1450 CIG75_RS19000 0b1e63fd7940b17d63fc93aa6232a033 123 Pfam PF05135 Phage gp6-like head-tail connector protein 12 52 2.1E-4 T 28-03-2018 IPR021146 Phage gp6-like head-tail connector protein CIG75_RS11005 8a6a7f1a206eeaadc3e579ebe2fb248d 908 Pfam PF04738 Lantibiotic dehydratase, C terminus 154 815 4.0E-45 T 28-03-2018 IPR006827 Lantibiotic dehydratase, C-terminal CIG75_RS17905 d624e566bfc845ce383bac42fbd5e813 281 Gene3D G3DSA:3.40.190.10 175 275 1.0E-14 T 28-03-2018 CIG75_RS17905 d624e566bfc845ce383bac42fbd5e813 281 Gene3D G3DSA:3.40.190.10 1 174 3.1E-77 T 28-03-2018 CIG75_RS17905 d624e566bfc845ce383bac42fbd5e813 281 Hamap MF_00996 1,4-dihydroxy-6-naphtoate synthase [mqnD]. 1 270 34.821 T 28-03-2018 IPR030869 1,4-dihydroxy-6-naphtoate synthase GO:0009234|GO:0016829 CIG75_RS17905 d624e566bfc845ce383bac42fbd5e813 281 Pfam PF02621 Menaquinone biosynthesis 1 264 1.4E-82 T 28-03-2018 IPR003773 Menaquinone biosynthesis enzyme CIG75_RS17905 d624e566bfc845ce383bac42fbd5e813 281 SUPERFAMILY SSF53850 1 269 5.32E-76 T 28-03-2018 CIG75_RS13930 8fcfe44a405e4f84b7ba27a210f182f8 216 TIGRFAM TIGR02896 spore_III_AF: stage III sporulation protein AF 3 113 2.6E-23 T 28-03-2018 IPR014245 Sporulation stage III, protein AF CIG75_RS13930 8fcfe44a405e4f84b7ba27a210f182f8 216 Pfam PF09581 Stage III sporulation protein AF (Spore_III_AF) 13 208 1.0E-33 T 28-03-2018 IPR014245 Sporulation stage III, protein AF CIG75_RS02150 9515e5b44360dd550a172fccdee471d8 298 Pfam PF01040 UbiA prenyltransferase family 45 264 1.1E-25 T 28-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 CIG75_RS16100 6502ab1a73cb2b05a3b7bb2f8ef62fab 267 Pfam PF11307 Protein of unknown function (DUF3109) 63 168 5.1E-9 T 28-03-2018 IPR021458 Protein of unknown function DUF3109 CIG75_RS11830 d4cc6f7c1794db53b27e32da7be3c789 208 Pfam PF00535 Glycosyl transferase family 2 4 120 6.1E-21 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CIG75_RS11830 d4cc6f7c1794db53b27e32da7be3c789 208 Gene3D G3DSA:3.90.550.10 1 208 6.0E-28 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CIG75_RS11830 d4cc6f7c1794db53b27e32da7be3c789 208 SUPERFAMILY SSF53448 2 199 3.25E-32 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CIG75_RS09715 8412d4dfc83a12672fe4240232ac980b 346 Gene3D G3DSA:1.25.40.10 40 337 6.8E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS11555 89235eade0cae12319aa8e425489dde7 86 Pfam PF04232 Stage V sporulation protein S (SpoVS) 2 84 4.0E-40 T 28-03-2018 IPR007347 Sporulation stage V, protein S CIG75_RS11555 89235eade0cae12319aa8e425489dde7 86 ProDom PD061837 SPORULATION V STAGE S SPOVS-RELATED SPOVS CELL SEPTATION SPOVS3 RELATED 3 86 5.0E-39 T 28-03-2018 IPR007347 Sporulation stage V, protein S CIG75_RS06505 d16c8c484fa6c81d4cf903bba8504132 308 Gene3D G3DSA:1.10.3470.10 1 281 5.3E-35 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CIG75_RS06505 d16c8c484fa6c81d4cf903bba8504132 308 Pfam PF02653 Branched-chain amino acid transport system / permease component 7 278 6.4E-32 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CIG75_RS15520 ee7bd25bb349b3055380eb3b35ad4654 113 Pfam PF13273 Protein of unknown function (DUF4064) 2 83 1.7E-11 T 28-03-2018 IPR025273 Domain of unknown function DUF4064 CIG75_RS01050 20fe2e883f031f685c06637eb3a21670 261 TIGRFAM TIGR02454 ECF_T_CbiQ: cobalt ECF transporter T component CbiQ 19 223 2.1E-45 T 28-03-2018 IPR012809 Cobalt ECF transporter T component CbiQ GO:0005887|GO:0006824|GO:0043190 CIG75_RS01050 20fe2e883f031f685c06637eb3a21670 261 Pfam PF02361 Cobalt transport protein 18 227 5.4E-36 T 28-03-2018 IPR003339 ABC/ECF transporter, transmembrane component CIG75_RS07930 c4d4597e3bc7e63ee2b68c481d7a4f66 141 SUPERFAMILY SSF103473 3 126 9.81E-5 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS10380 208109658acf07d9dc3c37000042b211 230 Gene3D G3DSA:1.10.10.10 1 227 6.4E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS10380 208109658acf07d9dc3c37000042b211 230 SUPERFAMILY SSF46785 18 146 2.97E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS10380 208109658acf07d9dc3c37000042b211 230 SUPERFAMILY SSF46785 2 57 2.33E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS19145 8ddc69044590207d75ee89d03260e75b 301 Pfam PF02151 UvrB/uvrC motif 263 287 1.1E-4 T 28-03-2018 IPR001943 UVR domain GO:0005515 CIG75_RS19145 8ddc69044590207d75ee89d03260e75b 301 Gene3D G3DSA:4.10.860.10 240 290 0.0019 T 28-03-2018 IPR001943 UVR domain GO:0005515 CIG75_RS13920 cac4f87a541a7d7d89c020af26715f67 170 Pfam PF12685 SpoIIIAH-like protein 42 166 6.7E-19 T 28-03-2018 IPR024232 Stage III sporulation protein AH-like CIG75_RS04075 e68b37e3af2e4897ab3bc9e42a5f90c4 210 Gene3D G3DSA:3.40.109.10 9 210 1.6E-49 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CIG75_RS04075 e68b37e3af2e4897ab3bc9e42a5f90c4 210 Pfam PF00881 Nitroreductase family 14 187 1.8E-32 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CIG75_RS04075 e68b37e3af2e4897ab3bc9e42a5f90c4 210 SUPERFAMILY SSF55469 10 204 5.37E-54 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CIG75_RS17970 a4798a4605616789ab1cb48ef6000ba6 276 Gene3D G3DSA:3.30.2140.10 1 270 4.2E-34 T 28-03-2018 CIG75_RS17970 a4798a4605616789ab1cb48ef6000ba6 276 Pfam PF00797 N-acetyltransferase 21 250 1.8E-14 T 28-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 CIG75_RS17970 a4798a4605616789ab1cb48ef6000ba6 276 SUPERFAMILY SSF54001 3 251 1.25E-37 T 28-03-2018 CIG75_RS05235 aac1ca880e34430ed641362b61e95658 210 Hamap MF_01851 UPF0637 protein . 5 205 33.827 T 28-03-2018 IPR009403 Protein of unknown function UPF0637 CIG75_RS05235 aac1ca880e34430ed641362b61e95658 210 PIRSF PIRSF021332 1 209 2.8E-72 T 28-03-2018 IPR009403 Protein of unknown function UPF0637 CIG75_RS05235 aac1ca880e34430ed641362b61e95658 210 Pfam PF06335 Protein of unknown function (DUF1054) 6 203 1.3E-73 T 28-03-2018 IPR009403 Protein of unknown function UPF0637 CIG75_RS05235 aac1ca880e34430ed641362b61e95658 210 SUPERFAMILY SSF142913 3 207 7.59E-72 T 28-03-2018 CIG75_RS09590 391ebcfce4c39d3c400d13c7de4e42cc 222 Gene3D G3DSA:3.40.50.410 22 199 4.7E-9 T 28-03-2018 IPR002035 von Willebrand factor, type A CIG75_RS09590 391ebcfce4c39d3c400d13c7de4e42cc 222 Pfam PF10138 vWA found in TerF C terminus 25 221 1.2E-79 T 28-03-2018 IPR019303 vWA found in TerF C terminus CIG75_RS09590 391ebcfce4c39d3c400d13c7de4e42cc 222 SUPERFAMILY SSF53300 27 195 2.02E-10 T 28-03-2018 IPR002035 von Willebrand factor, type A CIG75_RS09590 391ebcfce4c39d3c400d13c7de4e42cc 222 SMART SM00327 24 193 8.8E-4 T 28-03-2018 IPR002035 von Willebrand factor, type A CIG75_RS04525 2c82154e3f45b1185854219c926b8a34 292 Pfam PF13527 Acetyltransferase (GNAT) domain 22 132 4.3E-19 T 28-03-2018 CIG75_RS04525 2c82154e3f45b1185854219c926b8a34 292 SUPERFAMILY SSF55729 18 255 2.1E-33 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CIG75_RS04525 2c82154e3f45b1185854219c926b8a34 292 Gene3D G3DSA:3.40.630.30 4 146 7.3E-15 T 28-03-2018 CIG75_RS08235 bcdf2446824c70d4c3c94919dbf8c9de 302 Gene3D G3DSA:3.40.190.10 139 281 8.4E-25 T 28-03-2018 CIG75_RS08235 bcdf2446824c70d4c3c94919dbf8c9de 302 Gene3D G3DSA:3.40.190.10 32 138 1.4E-9 T 28-03-2018 CIG75_RS08235 bcdf2446824c70d4c3c94919dbf8c9de 302 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 44 286 5.4E-68 T 28-03-2018 CIG75_RS08235 bcdf2446824c70d4c3c94919dbf8c9de 302 SMART SM00062 41 277 8.6E-4 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CIG75_RS08235 bcdf2446824c70d4c3c94919dbf8c9de 302 SUPERFAMILY SSF53850 39 300 2.84E-39 T 28-03-2018 CIG75_RS08235 bcdf2446824c70d4c3c94919dbf8c9de 302 TIGRFAM TIGR01098 3A0109s03R: phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein 3 259 7.6E-69 T 28-03-2018 IPR005770 Phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein GO:0043190|GO:0055085 CIG75_RS04675 0b22cac52c3dd97efee59ebc5135c36b 118 Pfam PF03960 ArsC family 34 111 2.2E-10 T 28-03-2018 IPR006660 Arsenate reductase-like CIG75_RS04675 0b22cac52c3dd97efee59ebc5135c36b 118 SUPERFAMILY SSF52833 4 114 3.77E-22 T 28-03-2018 IPR012336 Thioredoxin-like fold CIG75_RS04675 0b22cac52c3dd97efee59ebc5135c36b 118 Gene3D G3DSA:3.40.30.10 1 113 9.6E-20 T 28-03-2018 CIG75_RS05130 dc8e740110b8252779011b92cb082bfb 283 Pfam PF14478 Domain of unknown function (DUF4430) 22 96 2.3E-14 T 28-03-2018 IPR027954 Domain of unknown function DUF4430 Reactome: R-HSA-196741 CIG75_RS07100 67a809d540302ff818c9eec3539353f5 143 SMART SM00529 19 118 3.6E-31 T 28-03-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 CIG75_RS07100 67a809d540302ff818c9eec3539353f5 143 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 58 119 1.1E-13 T 28-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 CIG75_RS07100 67a809d540302ff818c9eec3539353f5 143 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 1 55 7.1E-20 T 28-03-2018 IPR022687 DTXR-type HTH domain GO:0003677 CIG75_RS07100 67a809d540302ff818c9eec3539353f5 143 Gene3D G3DSA:1.10.60.10 70 131 1.9E-18 T 28-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 CIG75_RS07100 67a809d540302ff818c9eec3539353f5 143 SUPERFAMILY SSF47979 58 127 1.22E-13 T 28-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 CIG75_RS07100 67a809d540302ff818c9eec3539353f5 143 Gene3D G3DSA:1.10.10.10 1 66 9.8E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS07100 67a809d540302ff818c9eec3539353f5 143 SUPERFAMILY SSF46785 1 57 9.67E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS04985 4784d02d59b621fe6f1e5177c65cd046 365 Gene3D G3DSA:3.40.710.10 1 365 4.3E-63 T 28-03-2018 CIG75_RS04985 4784d02d59b621fe6f1e5177c65cd046 365 SUPERFAMILY SSF56601 2 353 1.05E-57 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CIG75_RS04985 4784d02d59b621fe6f1e5177c65cd046 365 Pfam PF00144 Beta-lactamase 2 345 1.3E-43 T 28-03-2018 IPR001466 Beta-lactamase-related CIG75_RS03115 2e632243cefd42ccc495d1afcc1c2b56 470 Pfam PF04984 Phage tail sheath protein subtilisin-like domain 203 361 1.6E-15 T 28-03-2018 IPR035089 Tail sheath protein, subtilisin-like domain CIG75_RS03115 2e632243cefd42ccc495d1afcc1c2b56 470 Pfam PF17482 Phage tail sheath C-terminal domain 369 468 1.0E-9 T 28-03-2018 IPR020287 Tail sheath protein, C-terminal domain CIG75_RS03115 2e632243cefd42ccc495d1afcc1c2b56 470 ProDom PD032508 PHAGE-LIKE PBSX XKDK ELEMENT PHAGE LIN1278 SHEATH YQBL RELATED TAIL 355 468 3.0E-6 T 28-03-2018 IPR020287 Tail sheath protein, C-terminal domain CIG75_RS00700 6864cc495afa1b9e6b1f49b3cfaf4fd5 61 Gene3D G3DSA:1.10.3910.10 1 53 0.0026 T 28-03-2018 CIG75_RS05135 c3937df43c418e208d5581d9123b3dc1 291 Pfam PF02361 Cobalt transport protein 17 216 2.7E-14 T 28-03-2018 IPR003339 ABC/ECF transporter, transmembrane component CIG75_RS06575 d07f7bd1f439fca38a473ff804c78580 344 Gene3D G3DSA:3.40.50.1820 58 341 4.1E-32 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS06575 d07f7bd1f439fca38a473ff804c78580 344 SUPERFAMILY SSF53474 16 313 1.41E-39 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS06575 d07f7bd1f439fca38a473ff804c78580 344 Pfam PF12146 Serine aminopeptidase, S33 85 208 1.1E-11 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 CIG75_RS04135 1437b2eb29b2537a670fee12e553d4f8 107 Gene3D G3DSA:1.10.287.1080 4 85 4.1E-4 T 28-03-2018 CIG75_RS04135 1437b2eb29b2537a670fee12e553d4f8 107 SUPERFAMILY SSF101386 22 84 1.87E-5 T 28-03-2018 CIG75_RS01850 3298683b070bb89bccc9828347b19e72 246 Pfam PF02535 ZIP Zinc transporter 104 239 2.1E-17 T 28-03-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 CIG75_RS07145 08f42b4241dcce2a3ec2cde25368c932 450 Pfam PF13490 Putative zinc-finger 4 36 4.6E-6 T 28-03-2018 IPR027383 Putative zinc-finger CIG75_RS14890 fa0e0df28d6eeb1149dc3f7c9b71f6ba 95 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 7 83 5.0E-21 T 28-03-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 CIG75_RS16310 35338b17e7d517bf36e9434ae4c0e8a9 462 Pfam PF01943 Polysaccharide biosynthesis protein 21 287 1.2E-11 T 28-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 CIG75_RS01730 3473236baca731bcb688368eb70e595c 271 Gene3D G3DSA:3.20.20.70 1 271 6.6E-115 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CIG75_RS01730 3473236baca731bcb688368eb70e595c 271 Pfam PF05853 beta-keto acid cleavage enzyme 3 269 2.1E-115 T 28-03-2018 IPR008567 3-keto-5-aminohexanoate cleavage enzyme GO:0016740|GO:0019475 KEGG: 00310+2.3.1.247|KEGG: 00600+2.3.1.24 CIG75_RS07540 e7bfc3a1e1d6840d74870fb8332a826b 213 SUPERFAMILY SSF46785 8 188 2.11E-35 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS07540 e7bfc3a1e1d6840d74870fb8332a826b 213 Pfam PF08279 HTH domain 9 49 3.7E-9 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 CIG75_RS07540 e7bfc3a1e1d6840d74870fb8332a826b 213 Gene3D G3DSA:1.10.10.10 4 153 3.5E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CIG75_RS17810 ae41b4c3a6c0840b99d6578a3df61e55 136 SUPERFAMILY SSF54593 3 130 4.93E-28 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CIG75_RS17810 ae41b4c3a6c0840b99d6578a3df61e55 136 Gene3D G3DSA:3.10.180.10 1 136 4.0E-25 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CIG75_RS17810 ae41b4c3a6c0840b99d6578a3df61e55 136 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 10 128 2.6E-8 T 28-03-2018 IPR028973 PhnB-like CIG75_RS09810 24c1752aa07eff03a2863539cc9489e3 161 Gene3D G3DSA:3.40.630.30 1 140 4.5E-20 T 28-03-2018 CIG75_RS09810 24c1752aa07eff03a2863539cc9489e3 161 SUPERFAMILY SSF55729 4 128 2.06E-21 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CIG75_RS09810 24c1752aa07eff03a2863539cc9489e3 161 Pfam PF00583 Acetyltransferase (GNAT) family 16 120 1.5E-15 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CIG75_RS15400 b63d7388c9a8daf444f4f36ebd802e9d 724 Gene3D G3DSA:3.40.720.10 23 282 7.8E-6 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CIG75_RS15400 b63d7388c9a8daf444f4f36ebd802e9d 724 Gene3D G3DSA:3.40.720.10 283 364 0.029 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CIG75_RS15400 b63d7388c9a8daf444f4f36ebd802e9d 724 SUPERFAMILY SSF53649 27 87 1.31E-8 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CIG75_RS15400 b63d7388c9a8daf444f4f36ebd802e9d 724 SUPERFAMILY SSF53649 148 347 1.31E-8 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CIG75_RS04115 12bdd4da106b263abc187b4a8d3404ed 78 Gene3D G3DSA:1.20.58.340 2 76 2.9E-4 T 28-03-2018 CIG75_RS14025 a30c835ece90af18623149d50b0c8b75 139 SUPERFAMILY SSF53474 38 130 2.25E-5 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CIG75_RS16575 3f249c00398a474025d41630d1219cf4 440 Gene3D G3DSA:3.50.50.60 1 433 4.0E-32 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS16575 3f249c00398a474025d41630d1219cf4 440 Pfam PF01593 Flavin containing amine oxidoreductase 12 260 1.6E-19 T 28-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 CIG75_RS16575 3f249c00398a474025d41630d1219cf4 440 SUPERFAMILY SSF51905 1 281 1.65E-41 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS16575 3f249c00398a474025d41630d1219cf4 440 SUPERFAMILY SSF51905 388 427 1.65E-41 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS11200 52efc4713682834c4a336fe01f9859c1 750 Pfam PF04865 Baseplate J-like protein 467 672 1.5E-17 T 28-03-2018 IPR006949 Baseplate protein J-like CIG75_RS11200 52efc4713682834c4a336fe01f9859c1 750 TIGRFAM TIGR02243 TIGR02243: putative baseplate assembly protein 389 709 7.6E-67 T 28-03-2018 IPR011749 Conserved hypothetical protein CHP02243 CIG75_RS03770 814fc654fd560c95b721eeb50b2b829a 213 SUPERFAMILY SSF48371 41 195 6.17E-13 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 CIG75_RS03770 814fc654fd560c95b721eeb50b2b829a 213 Gene3D G3DSA:1.25.10.10 10 212 1.6E-13 T 28-03-2018 IPR011989 Armadillo-like helical CIG75_RS02865 922246f965d642da92acf766cf840a37 618 Pfam PF04183 IucA / IucC family 159 407 1.0E-68 T 28-03-2018 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0015343|GO:0019290 CIG75_RS02865 922246f965d642da92acf766cf840a37 618 Pfam PF06276 Ferric iron reductase FhuF-like transporter 426 599 3.2E-36 T 28-03-2018 IPR022770 Ferric iron reductase FhuF domain CIG75_RS08720 bbb7f765ccc6fe0e4b40f01b4e4afc91 116 Pfam PF03862 SpoVAC/SpoVAEB sporulation membrane protein 3 110 3.2E-40 T 28-03-2018 IPR005562 SpoVA CIG75_RS08720 bbb7f765ccc6fe0e4b40f01b4e4afc91 116 TIGRFAM TIGR02839 spore_V_AE: stage V sporulation protein AE 3 116 3.2E-51 T 28-03-2018 IPR014204 Sporulation stage V, protein AE CIG75_RS07705 c2650e5b861a63fa4af926dd52556b78 364 SUPERFAMILY SSF51735 131 265 1.32E-16 T 28-03-2018 IPR016040 NAD(P)-binding domain CIG75_RS07705 c2650e5b861a63fa4af926dd52556b78 364 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 144 254 6.4E-10 T 28-03-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase CIG75_RS07705 c2650e5b861a63fa4af926dd52556b78 364 Gene3D G3DSA:3.40.50.720 123 274 2.8E-20 T 28-03-2018 CIG75_RS03120 f2bb6661525e51880fc5382443230d1e 150 SUPERFAMILY SSF69279 8 140 2.89E-28 T 28-03-2018 CIG75_RS03120 f2bb6661525e51880fc5382443230d1e 150 Pfam PF09393 Phage tail tube protein 2 138 2.0E-32 T 28-03-2018 IPR018989 Phage tail tube protein CIG75_RS12045 3354359d142f433f9bf01453554e123a 148 Pfam PF02050 Flagellar FliJ protein 21 140 4.9E-7 T 28-03-2018 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 CIG75_RS16380 623cee28a07504ae42f3e1586ed5b7e3 69 Pfam PF07561 Domain of Unknown Function (DUF1540) 4 64 1.4E-13 T 28-03-2018 IPR011437 Domain of unknown function DUF1540 CIG75_RS13620 b564839551d7cc0fe16043e500217388 158 Gene3D G3DSA:3.10.120.10 19 54 0.014 T 28-03-2018 IPR001199 Cytochrome b5-like heme/steroid binding domain CIG75_RS02735 ab509d274fa3a7409d6dc621eb423073 325 Pfam PF13349 Putative adhesin 55 322 4.7E-36 T 28-03-2018 IPR025164 Putative adhesin CIG75_RS16285 1760d46d8109af42feb097c456f55712 96 Pfam PF09527 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter 33 84 8.0E-14 T 28-03-2018 IPR032820 Putative F0F1-ATPase subunit, Ca2+/Mg2+ transporter CIG75_RS16985 7b27d4ca91ce823250a442086fcf9d09 77 Pfam PF14169 Cold-inducible protein YdjO 1 59 1.2E-28 T 28-03-2018 IPR025916 Cold-inducible protein YdjO CIG75_RS18950 df50226d8278db9f2f45a70dfc09cb14 736 Gene3D G3DSA:1.20.5.1230 2 676 1.5E-4 T 28-03-2018 CIG75_RS15105 9e6e2ec210668c868545edb5139f0ccb 261 Pfam PF06182 ABC-2 family transporter protein 37 260 5.1E-55 T 28-03-2018 IPR010390 Protein of unknown function DUF990 CIG75_RS03545 25a81476698e859bc8265d1262d182b9 342 Gene3D G3DSA:3.40.1710.10 1 166 1.1E-14 T 28-03-2018 CIG75_RS03545 25a81476698e859bc8265d1262d182b9 342 Pfam PF12698 ABC-2 family transporter protein 15 333 5.0E-34 T 28-03-2018 CIG75_RS09730 401ed76ed75000a100668e5f4063fc8c 526 Pfam PF16933 Putative exopolysaccharide Exporter (EPS-E) 1 454 1.6E-95 T 28-03-2018 IPR031617 Putative exopolysaccharide exporter CIG75_RS03790 1338ce123ebb08a9d5c1a6e46baf2826 151 SUPERFAMILY SSF55961 10 147 6.88E-20 T 28-03-2018 CIG75_RS03790 1338ce123ebb08a9d5c1a6e46baf2826 151 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 9 146 3.7E-14 T 28-03-2018 IPR019587 Polyketide cyclase/dehydrase CIG75_RS03790 1338ce123ebb08a9d5c1a6e46baf2826 151 Gene3D G3DSA:3.30.530.20 8 151 5.9E-17 T 28-03-2018 IPR023393 START-like domain CIG75_RS05070 61dbb44ff84f2a076b70505eaa942913 245 Pfam PF02096 60Kd inner membrane protein 28 212 3.4E-31 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CIG75_RS05070 61dbb44ff84f2a076b70505eaa942913 245 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 28 211 2.4E-30 T 28-03-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal CIG75_RS18875 736708c917cc71550f6bba3872df2256 106 Pfam PF08863 YolD-like protein 14 77 2.5E-13 T 28-03-2018 IPR014962 YolD-like protein CIG75_RS11635 7ed8f233b1394540bb49b017839cfa48 404 Pfam PF07690 Major Facilitator Superfamily 22 319 1.1E-15 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CIG75_RS11635 7ed8f233b1394540bb49b017839cfa48 404 SUPERFAMILY SSF103473 17 395 2.49E-27 T 28-03-2018 IPR020846 Major facilitator superfamily domain CIG75_RS11635 7ed8f233b1394540bb49b017839cfa48 404 Gene3D G3DSA:1.20.1250.20 6 197 7.9E-21 T 28-03-2018 CIG75_RS11635 7ed8f233b1394540bb49b017839cfa48 404 Gene3D G3DSA:1.20.1250.20 208 400 9.1E-4 T 28-03-2018 CIG75_RS04185 981450334cd85781538ba8529f3a907b 150 Gene3D G3DSA:3.10.180.10 3 136 6.1E-20 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CIG75_RS04185 981450334cd85781538ba8529f3a907b 150 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 114 5.0E-11 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CIG75_RS04185 981450334cd85781538ba8529f3a907b 150 SUPERFAMILY SSF54593 4 119 4.83E-24 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CIG75_RS08525 8d87899c2f6c7b623dbbd489490d06e0 371 Pfam PF12982 Protein of unknown function (DUF3866) 18 343 5.1E-126 T 28-03-2018 IPR024479 Protein of unknown function DUF3866 CIG75_RS02290 51d43389f28711b0b56fd9925dd283db 352 Gene3D G3DSA:3.90.70.10 168 349 3.1E-9 T 28-03-2018 CIG75_RS08970 c64c4e785212ff6d6d44c63a3ee74822 272 Pfam PF10977 Protein of unknown function (DUF2797) 37 260 4.8E-85 T 28-03-2018 IPR021246 Protein of unknown function DUF2797 CIG75_RS02390 cd7ce56a134770419caa9588b910b062 507 Pfam PF07195 Flagellar hook-associated protein 2 C-terminus 233 492 1.5E-42 T 28-03-2018 IPR010809 Flagellar hook-associated 2, C-terminal GO:0007155|GO:0009288 CIG75_RS02390 cd7ce56a134770419caa9588b910b062 507 Pfam PF02465 Flagellar hook-associated protein 2 N-terminus 14 111 1.2E-18 T 28-03-2018 IPR003481 Flagellar hook-associated protein 2, N-terminal GO:0009424 CIG75_RS01035 e8fd17943d966da76c8b43262192d386 252 SUPERFAMILY SSF52540 2 225 1.49E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS01035 e8fd17943d966da76c8b43262192d386 252 SMART SM00382 26 213 8.7E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS01035 e8fd17943d966da76c8b43262192d386 252 Gene3D G3DSA:3.40.50.300 1 233 3.0E-62 T 28-03-2018 CIG75_RS01035 e8fd17943d966da76c8b43262192d386 252 Pfam PF00005 ABC transporter 18 164 1.4E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS14430 14da4d58970d64a2609c9295aa97525b 81 Pfam PF10676 Spore germination protein gerPA/gerPF 5 66 2.7E-6 T 28-03-2018 IPR019618 Spore germination protein GerPA/GerPF CIG75_RS00290 19ff74750b6c946a48b42c51dbb1f166 236 Pfam PF04474 Protein of unknown function (DUF554) 4 227 3.8E-74 T 28-03-2018 IPR007563 Protein of unknown function DUF554 CIG75_RS05415 f0901613e900d5f523621842f060cfac 230 Pfam PF03787 RAMP superfamily 16 178 9.4E-8 T 28-03-2018 IPR005537 CRISPR type III-associated RAMP protein CIG75_RS03040 b83597675cd545753ad290921280c408 255 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 4 250 1.2E-43 T 28-03-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 CIG75_RS03040 b83597675cd545753ad290921280c408 255 Gene3D G3DSA:3.40.830.10 1 255 2.1E-83 T 28-03-2018 CIG75_RS03040 b83597675cd545753ad290921280c408 255 SUPERFAMILY SSF53213 1 255 1.24E-85 T 28-03-2018 CIG75_RS03040 b83597675cd545753ad290921280c408 255 PIRSF PIRSF006157 1 255 9.9E-96 T 28-03-2018 IPR014436 Extradiol aromatic ring-opening dioxygenase, DODA-type GO:0008270|GO:0016701|GO:0055114 CIG75_RS12810 f67581a036b6b5a3ce97f33ac83f4bb9 306 Gene3D G3DSA:1.10.10.60 8 300 7.1E-4 T 28-03-2018 CIG75_RS12810 f67581a036b6b5a3ce97f33ac83f4bb9 306 Pfam PF10668 Phage terminase small subunit 2 62 3.4E-14 T 28-03-2018 IPR018925 Phage terminase small subunit CIG75_RS02575 412d978c128d940d56161b6994f89540 967 SUPERFAMILY SSF52540 181 275 3.54E-7 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS02575 412d978c128d940d56161b6994f89540 967 SUPERFAMILY SSF52540 58 101 3.54E-7 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS02575 412d978c128d940d56161b6994f89540 967 Gene3D G3DSA:3.40.50.300 40 789 2.5E-6 T 28-03-2018 CIG75_RS04395 9ea03ed9f2d62939f105568669c29380 531 SUPERFAMILY SSF55486 3 528 1.37E-80 T 28-03-2018 CIG75_RS04395 9ea03ed9f2d62939f105568669c29380 531 Gene3D G3DSA:1.10.1370.10 26 528 8.9E-40 T 28-03-2018 CIG75_RS04395 9ea03ed9f2d62939f105568669c29380 531 Pfam PF01401 Angiotensin-converting enzyme 3 478 9.6E-20 T 28-03-2018 IPR001548 Peptidase M2, peptidyl-dipeptidase A GO:0006508|GO:0008237|GO:0008241|GO:0016020 CIG75_RS04210 49dae430aa1ccd8a202ee8e0c7da8160 190 Pfam PF07552 Spore Coat Protein X and V domain 70 125 3.0E-17 T 28-03-2018 IPR011428 Spore coat protein X/V GO:0030435|GO:0031160 CIG75_RS04210 49dae430aa1ccd8a202ee8e0c7da8160 190 Pfam PF07552 Spore Coat Protein X and V domain 132 189 3.2E-15 T 28-03-2018 IPR011428 Spore coat protein X/V GO:0030435|GO:0031160 CIG75_RS04380 1989fafe955bb476b8a4b84c90ce2f06 79 Pfam PF06803 Protein of unknown function (DUF1232) 24 57 2.1E-14 T 28-03-2018 IPR010652 Protein of unknown function DUF1232 CIG75_RS10055 fb493f5c8364f242a63cddab0de247f3 725 Gene3D G3DSA:2.60.40.1730 298 504 1.2E-4 T 28-03-2018 CIG75_RS11295 7915d84a3b83f07b1798a434bdd7f72e 146 Pfam PF09350 Domain of unknown function (DUF1992) 30 93 1.5E-11 T 28-03-2018 IPR018961 DnaJ homologue, subfamily C, member 28, conserved domain CIG75_RS14935 13126077e771ba8f905f134476783c89 240 Pfam PF00925 GTP cyclohydrolase II 74 215 5.9E-45 T 28-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CIG75_RS14935 13126077e771ba8f905f134476783c89 240 SUPERFAMILY SSF142695 75 217 1.96E-45 T 28-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CIG75_RS10965 83671db83e4e8486654c43922309ac75 244 SMART SM00382 31 217 6.5E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CIG75_RS10965 83671db83e4e8486654c43922309ac75 244 SUPERFAMILY SSF52540 4 222 2.77E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS10965 83671db83e4e8486654c43922309ac75 244 Pfam PF00005 ABC transporter 23 160 5.1E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CIG75_RS10965 83671db83e4e8486654c43922309ac75 244 Gene3D G3DSA:3.40.50.300 3 231 3.2E-66 T 28-03-2018 CIG75_RS10690 197a5a7b8e09f20eecb1b2e50ce33bb6 186 Gene3D G3DSA:3.40.630.30 1 186 1.3E-25 T 28-03-2018 CIG75_RS10690 197a5a7b8e09f20eecb1b2e50ce33bb6 186 SUPERFAMILY SSF55729 2 183 6.73E-25 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CIG75_RS10690 197a5a7b8e09f20eecb1b2e50ce33bb6 186 Pfam PF00583 Acetyltransferase (GNAT) family 53 165 1.6E-15 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CIG75_RS17585 efe9ce7de64daee3c2aaf6acfe35d030 218 Pfam PF04893 Yip1 domain 7 208 5.1E-17 T 28-03-2018 IPR006977 Yip1 domain GO:0016020 CIG75_RS19290 c206719d8051096f9dbdba97577112c9 275 SUPERFAMILY SSF55729 95 264 7.7E-16 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CIG75_RS19290 c206719d8051096f9dbdba97577112c9 275 Gene3D G3DSA:3.40.630.30 133 275 1.9E-15 T 28-03-2018 CIG75_RS07150 aba9b8ea34c2bd5b68cc96fb6feff444 203 Gene3D G3DSA:3.40.190.10 1 159 0.0016 T 28-03-2018 CIG75_RS17975 c13672d271af0841803ecacc91856d2c 316 Pfam PF12679 ABC-2 family transporter protein 3 314 1.0E-17 T 28-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 CIG75_RS15360 ca455cf4358c44c2b16aaa47425ede5d 344 Pfam PF01594 AI-2E family transporter 8 335 1.8E-54 T 28-03-2018 IPR002549 Transmembrane protein TqsA-like CIG75_RS15360 ca455cf4358c44c2b16aaa47425ede5d 344 TIGRFAM TIGR02872 spore_ytvI: sporulation integral membrane protein YtvI 8 337 6.0E-93 T 28-03-2018 IPR014227 Sporulation integral membrane protein YtvI CIG75_RS20390 7d292f8bdb5e7fade1a97c34fe302304 170 SUPERFAMILY SSF52833 12 155 6.73E-6 T 28-03-2018 IPR012336 Thioredoxin-like fold CIG75_RS20390 7d292f8bdb5e7fade1a97c34fe302304 170 Gene3D G3DSA:3.40.30.10 37 169 7.2E-6 T 28-03-2018 CIG75_RS16425 3f411bf5bb6abbf7eb9fe7c65737df4a 232 Pfam PF14343 PrcB C-terminal 159 215 6.5E-14 T 28-03-2018 IPR025748 PrcB C-terminal domain CIG75_RS01490 7b18410f699921c91faf9143ef2bede0 158 SUPERFAMILY SSF75169 7 50 7.8E-23 T 28-03-2018 IPR027396 DsrEFH-like CIG75_RS01490 7b18410f699921c91faf9143ef2bede0 158 SUPERFAMILY SSF75169 100 152 7.8E-23 T 28-03-2018 IPR027396 DsrEFH-like CIG75_RS01490 7b18410f699921c91faf9143ef2bede0 158 Pfam PF13686 DsrE/DsrF/DrsH-like family 3 157 6.6E-60 T 28-03-2018 IPR032836 DsrE2-like family CIG75_RS01490 7b18410f699921c91faf9143ef2bede0 158 Gene3D G3DSA:3.40.1260.10 1 158 9.2E-54 T 28-03-2018 CIG75_RS17755 9944caa8038661cde5a792efb6c84269 435 Pfam PF09335 SNARE associated Golgi protein 49 146 1.5E-12 T 28-03-2018 IPR032816 SNARE associated Golgi protein CIG75_RS11500 f8ea8d7acf15cf815c96fd779f2c5844 178 Pfam PF10628 Outer spore coat protein E (CotE) 10 172 2.5E-52 T 28-03-2018 IPR018901 Spore coat protein CotE CIG75_RS12695 fc65a8b2e73a4e4c6c2f4b90483f9f4b 85 Pfam PF10960 BhlA holin family 3 72 2.2E-10 T 28-03-2018 IPR024405 Prophage protein BhlA/UviB CIG75_RS12695 fc65a8b2e73a4e4c6c2f4b90483f9f4b 85 ProDom PD019268 UVIB BACTERIOCIN BHLA PLASMID ANTIBIOTIC HOLIN-LIKE PRECURSOR ANTIMICROBIAL SIGNAL PROPHAGE-DERIVED 2 51 0.003 T 28-03-2018 IPR024405 Prophage protein BhlA/UviB CIG75_RS19160 c7a56ddd8bbb4cac8d1bf481b09b28c1 148 Pfam PF06356 Protein of unknown function (DUF1064) 3 111 9.9E-38 T 28-03-2018 IPR009414 Protein of unknown function DUF1064 CIG75_RS19160 c7a56ddd8bbb4cac8d1bf481b09b28c1 148 Gene3D G3DSA:3.40.91.30 15 145 1.9E-17 T 28-03-2018 CIG75_RS19010 18c6352573f86f7c08c02d5530b47935 129 Gene3D G3DSA:2.40.300.10 3 128 1.6E-4 T 28-03-2018 CIG75_RS10850 a6a4311fc4a53a46a27ab1b00ecbd05b 140 SUPERFAMILY SSF158622 12 103 9.03E-13 T 28-03-2018 IPR023378 YheA/YmcA-like domain CIG75_RS10850 a6a4311fc4a53a46a27ab1b00ecbd05b 140 Gene3D G3DSA:1.20.1500.10 60 102 0.022 T 28-03-2018 IPR023378 YheA/YmcA-like domain CIG75_RS10850 a6a4311fc4a53a46a27ab1b00ecbd05b 140 Gene3D G3DSA:1.20.1500.10 11 59 3.4E-6 T 28-03-2018 IPR023378 YheA/YmcA-like domain CIG75_RS10850 a6a4311fc4a53a46a27ab1b00ecbd05b 140 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 13 99 1.6E-9 T 28-03-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA CIG75_RS10515 56a98115eb5751d74913c24d043de30c 79 SUPERFAMILY SSF52833 5 75 3.14E-16 T 28-03-2018 IPR012336 Thioredoxin-like fold CIG75_RS10515 56a98115eb5751d74913c24d043de30c 79 Pfam PF00462 Glutaredoxin 6 64 3.7E-11 T 28-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 CIG75_RS10515 56a98115eb5751d74913c24d043de30c 79 Gene3D G3DSA:3.40.30.10 1 18 0.17 T 28-03-2018 CIG75_RS10515 56a98115eb5751d74913c24d043de30c 79 Gene3D G3DSA:3.40.30.10 19 74 5.4E-16 T 28-03-2018 CIG75_RS00695 e9ec9527863457bd7d6af83cd882b4f6 253 Pfam PF01939 Endonuclease NucS 98 228 7.8E-12 T 28-03-2018 IPR002793 Endonuclease NucS CIG75_RS13630 1fbc6239e896a182a3368a06d5754eb3 84 Pfam PF07293 Protein of unknown function (DUF1450) 7 79 1.6E-18 T 28-03-2018 IPR009910 Protein of unknown function DUF1450 CIG75_RS13630 1fbc6239e896a182a3368a06d5754eb3 84 ProDom PD058324 UPF0349 LMO2392 BLI03401/BL03152 SA0800 SAR0901 LIN2491 SERP0525 GK2958 BT9727_4649 BC4937 6 63 1.0E-6 T 28-03-2018 CIG75_RS08310 146651c1a53e2ec9b25e6eccf6676d78 219 Gene3D G3DSA:3.40.470.10 5 217 9.7E-8 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CIG75_RS12460 6f9d80f271d81771991780a5a76a3d3d 121 Pfam PF03780 Asp23 family, cell envelope-related function 9 116 1.2E-33 T 28-03-2018 IPR005531 Alkaline shock protein Asp23 CIG75_RS11905 05f767e10e91c2e9b128d22ee1457d6b 188 Gene3D G3DSA:1.20.5.50 26 129 7.0E-4 T 28-03-2018 CIG75_RS11905 05f767e10e91c2e9b128d22ee1457d6b 188 Gene3D G3DSA:1.10.10.60 142 176 1.7E-5 T 28-03-2018 CIG75_RS02780 8a2d4a87ea5711adcd35a4051bded515 243 Pfam PF01061 ABC-2 type transporter 13 210 1.1E-12 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CIG75_RS18965 94f628f2b840b430e52d69e6d3dd1e2a 155 Pfam PF09393 Phage tail tube protein 5 147 2.6E-43 T 28-03-2018 IPR018989 Phage tail tube protein CIG75_RS18965 94f628f2b840b430e52d69e6d3dd1e2a 155 SUPERFAMILY SSF69279 8 149 1.09E-40 T 28-03-2018 CIG75_RS14090 251f13732dcb1544fcff78d670392143 90 Pfam PF11256 Protein of unknown function (DUF3055) 5 84 9.0E-28 T 28-03-2018 IPR021415 Protein of unknown function DUF3055 CIG75_RS10335 fa36a70980b544c6b3d43b7c2164ab2b 366 Pfam PF03845 Spore germination protein 13 319 2.9E-31 T 28-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 CIG75_RS10335 fa36a70980b544c6b3d43b7c2164ab2b 366 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 7 358 1.9E-60 T 28-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 CIG75_RS20395 dd9857630d6aafb9a37213b795031d27 325 SUPERFAMILY SSF101898 52 315 4.18E-14 T 28-03-2018 CIG75_RS20395 dd9857630d6aafb9a37213b795031d27 325 Gene3D G3DSA:2.120.10.30 38 203 4.8E-12 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CIG75_RS20395 dd9857630d6aafb9a37213b795031d27 325 Gene3D G3DSA:2.120.10.30 204 322 0.0024 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CIG75_RS09530 861d3e62e1fd88ce904db11f0770deca 73 Gene3D G3DSA:3.50.50.60 3 71 3.7E-5 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS09530 861d3e62e1fd88ce904db11f0770deca 73 SUPERFAMILY SSF51905 27 71 1.54E-6 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CIG75_RS16450 72fa26d4c759f6e7fda7780f0c060215 73 Pfam PF10676 Spore germination protein gerPA/gerPF 2 71 2.7E-25 T 28-03-2018 IPR019618 Spore germination protein GerPA/GerPF CIG75_RS16225 5910cbd51bc51907d5c7c67c522e0558 554 Gene3D G3DSA:2.60.40.10 25 119 3.0E-5 T 28-03-2018 IPR013783 Immunoglobulin-like fold CIG75_RS16225 5910cbd51bc51907d5c7c67c522e0558 554 Pfam PF00395 S-layer homology domain 372 414 4.3E-7 T 28-03-2018 IPR001119 S-layer homology domain CIG75_RS16225 5910cbd51bc51907d5c7c67c522e0558 554 Pfam PF00395 S-layer homology domain 432 474 8.9E-6 T 28-03-2018 IPR001119 S-layer homology domain CIG75_RS10500 5f05522e6e11f02a517cdad32fd42860 190 Gene3D G3DSA:2.60.40.10 48 189 2.5E-5 T 28-03-2018 IPR013783 Immunoglobulin-like fold CIG75_RS20140 2b2f9fe13078826ae778a36ad0f882c3 403 Pfam PF13490 Putative zinc-finger 8 36 6.4E-6 T 28-03-2018 IPR027383 Putative zinc-finger CIG75_RS02145 9e8c40871fd36b45246557a65823809b 447 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 76 223 8.6E-11 T 28-03-2018 CIG75_RS07255 000d6518fc1effdd3de2b9b5f688574d 291 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 171 2.3E-24 T 28-03-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase CIG75_RS05410 f3af772a4f6da0feb05eccd9406b8190 726 Gene3D G3DSA:3.30.70.270 360 568 1.6E-5 T 28-03-2018 CIG75_RS11235 5647bb721b1531b5a0100f053ee53b28 147 TIGRFAM TIGR02241 TIGR02241: conserved hypothetical phage tail region protein 8 142 4.0E-42 T 28-03-2018 IPR011747 Conserved hypothetical protein CHP02241 CIG75_RS11235 5647bb721b1531b5a0100f053ee53b28 147 Pfam PF06841 T4-like virus tail tube protein gp19 12 142 2.8E-44 T 28-03-2018 IPR010667 Bacteriophage T4, Gp19, tail tube GO:0005198 CIG75_RS11345 5062bbdf50ed8364d27c05caaa100900 144 Pfam PF07179 SseB protein N-terminal domain 18 137 8.3E-13 T 28-03-2018 IPR009839 SseB protein N-terminal domain CIG75_RS02915 f362f24e97a0adc204e1379c1beabdc0 193 Gene3D G3DSA:2.60.60.30 19 187 2.9E-65 T 28-03-2018 CIG75_RS02915 f362f24e97a0adc204e1379c1beabdc0 193 Pfam PF02342 TerD domain 1 188 1.9E-86 T 28-03-2018 IPR003325 TerD domain GO:0006950 CIG75_RS19065 e381bf5fd898e2968a96a4a2a9b16999 170 Pfam PF11195 Protein of unknown function (DUF2829) 66 152 2.8E-19 T 28-03-2018 IPR021361 Protein of unknown function DUF2829 CIG75_RS11325 fbf49a3a23c04caa022fe24dbe681438 109 Pfam PF11750 Protein of unknown function (DUF3307) 3 105 2.9E-11 T 28-03-2018 IPR021737 Bacteriophage phiKZ, Orf197 CIG75_RS15230 de6fca28ffb13b27f832a07e4f51be81 438 SUPERFAMILY SSF53335 64 420 1.33E-81 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CIG75_RS15230 de6fca28ffb13b27f832a07e4f51be81 438 Gene3D G3DSA:3.40.50.150 117 337 1.7E-5 T 28-03-2018 CIG75_RS15230 de6fca28ffb13b27f832a07e4f51be81 438 Pfam PF02636 Putative S-adenosyl-L-methionine-dependent methyltransferase 117 354 2.2E-46 T 28-03-2018 IPR003788 Protein arginine methyltransferase NDUFAF7 Reactome: R-HSA-6799198 CIG75_RS02085 532bb1d702d11d781fb98d589a5ec687 226 Pfam PF00395 S-layer homology domain 163 200 3.2E-4 T 28-03-2018 IPR001119 S-layer homology domain CIG75_RS02085 532bb1d702d11d781fb98d589a5ec687 226 Pfam PF00395 S-layer homology domain 100 143 1.3E-9 T 28-03-2018 IPR001119 S-layer homology domain CIG75_RS02085 532bb1d702d11d781fb98d589a5ec687 226 Pfam PF00395 S-layer homology domain 35 78 3.6E-6 T 28-03-2018 IPR001119 S-layer homology domain CIG75_RS14755 57a52f1c302931847835124e22df0bd7 334 Pfam PF12127 SigmaW regulon antibacterial 10 320 5.3E-161 T 28-03-2018 IPR022853 Uncharacterised protein family YdfA-immunity CIG75_RS14755 57a52f1c302931847835124e22df0bd7 334 Hamap MF_01562 UPF0365 protein . 4 324 47.662 T 28-03-2018 IPR022853 Uncharacterised protein family YdfA-immunity CIG75_RS10325 c286059a98b7bc7362d96d2176b7c07e 390 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 226 380 6.4E-21 T 28-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 CIG75_RS10325 c286059a98b7bc7362d96d2176b7c07e 390 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 10 381 4.4E-70 T 28-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 CIG75_RS02485 c0cdd0ad08289cfd94513dd73c309ad1 256 Pfam PF01925 Sulfite exporter TauE/SafE 7 253 9.8E-47 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 CIG75_RS17395 74b174f6c8112766cfaa4aa7693863c9 264 Pfam PF01618 MotA/TolQ/ExbB proton channel family 102 216 2.0E-24 T 28-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 CIG75_RS15175 c36a2a889d88ec379511c0bd30ef4dfb 79 Gene3D G3DSA:1.20.1260.10 3 78 1.4E-8 T 28-03-2018 IPR012347 Ferritin-related CIG75_RS17350 feb993ccdef80b72edab65af35852385 315 Pfam PF07670 Nucleoside recognition 19 101 1.8E-7 T 28-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 CIG75_RS17350 feb993ccdef80b72edab65af35852385 315 Pfam PF07670 Nucleoside recognition 175 263 3.5E-8 T 28-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 CIG75_RS02855 9f26ac6ef9d1497f8f30778b8bed5000 621 Pfam PF04183 IucA / IucC family 166 407 4.0E-58 T 28-03-2018 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0015343|GO:0019290 CIG75_RS02855 9f26ac6ef9d1497f8f30778b8bed5000 621 Pfam PF06276 Ferric iron reductase FhuF-like transporter 452 590 3.9E-18 T 28-03-2018 IPR022770 Ferric iron reductase FhuF domain CIG75_RS11860 e36a6e0c5b3dafb387295ae12bce1f54 185 SUPERFAMILY SSF81301 5 150 6.54E-21 T 28-03-2018 CIG75_RS11225 432cde2517275a3b9987e467bc437b6d 210 Pfam PF01476 LysM domain 164 207 1.7E-7 T 28-03-2018 IPR018392 LysM domain CIG75_RS11225 432cde2517275a3b9987e467bc437b6d 210 Gene3D G3DSA:3.10.350.10 158 208 5.6E-9 T 28-03-2018 CIG75_RS20350 0ea28d19e00653a2d012598b27c622cd 264 Gene3D G3DSA:3.90.550.10 1 119 1.5E-7 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CIG75_RS20350 0ea28d19e00653a2d012598b27c622cd 264 SUPERFAMILY SSF53448 1 168 2.72E-12 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CIG75_RS11805 e28ef76088e073c79af4ecb78864af8b 108 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 5 93 4.5E-13 T 28-03-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 CIG75_RS11805 e28ef76088e073c79af4ecb78864af8b 108 Gene3D G3DSA:3.30.1330.30 3 101 3.6E-17 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CIG75_RS11805 e28ef76088e073c79af4ecb78864af8b 108 SUPERFAMILY SSF55315 5 99 5.3E-23 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CIG75_RS18400 e3b57a496b89424c26afb09bb3e9f81e 116 Pfam PF03862 SpoVAC/SpoVAEB sporulation membrane protein 3 111 6.4E-41 T 28-03-2018 IPR005562 SpoVA CIG75_RS18400 e3b57a496b89424c26afb09bb3e9f81e 116 TIGRFAM TIGR02839 spore_V_AE: stage V sporulation protein AE 3 116 7.4E-51 T 28-03-2018 IPR014204 Sporulation stage V, protein AE CIG75_RS17115 3e952624e2d0cceb2bf215793de43c5d 288 SUPERFAMILY SSF48452 146 268 6.68E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS17115 3e952624e2d0cceb2bf215793de43c5d 288 Gene3D G3DSA:1.25.40.10 23 228 7.8E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CIG75_RS20440 14f40964521be55891188b2e942786df 404 Pfam PF01098 Cell cycle protein 24 396 4.6E-84 T 28-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 CIG75_RS02960 b6c8a2eae3361fc5684f7831337366f8 366 Gene3D G3DSA:1.10.287.950 104 342 1.5E-4 T 28-03-2018 CIG75_RS02960 b6c8a2eae3361fc5684f7831337366f8 366 Pfam PF05816 Toxic anion resistance protein (TelA) 40 341 7.9E-39 T 28-03-2018 IPR008863 Toxic anion resistance CIG75_RS14375 f00322f31ab3cc65afbcf7132f2b6f64 369 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 196 366 5.4E-24 T 28-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 CIG75_RS11400 9ee9794e6e8c6a74c01ee74460b77862 264 Pfam PF09577 Sporulation protein YpjB (SpoYpjB) 40 263 1.3E-6 T 28-03-2018 IPR014231 Sporulation protein YpjB CIG75_RS08295 805695a560bff0210aa5178618ff83fb 149 Gene3D G3DSA:3.10.660.10 71 148 2.6E-4 T 28-03-2018 IPR007872 Zinc finger, DPH-type CIG75_RS05760 c3a54e9a4d82a96822204e3faab94770 334 Pfam PF01384 Phosphate transporter family 23 322 4.5E-90 T 28-03-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 CIG75_RS03910 2666bfb828570f42bb6912f709ccc70d 170 Gene3D G3DSA:3.40.50.300 2 163 1.2E-17 T 28-03-2018 CIG75_RS03910 2666bfb828570f42bb6912f709ccc70d 170 SUPERFAMILY SSF52540 3 134 1.94E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CIG75_RS08820 261f9ccf03a4800ebb31c19533be32cf 199 Pfam PF07670 Nucleoside recognition 42 148 7.5E-10 T 28-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 CIG75_RS18040 1a1307278d6ccf2593dfa6c2e88b2b37 187 SUPERFAMILY SSF55729 21 167 3.26E-24 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CIG75_RS18040 1a1307278d6ccf2593dfa6c2e88b2b37 187 Pfam PF00583 Acetyltransferase (GNAT) family 48 159 3.0E-14 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CIG75_RS18040 1a1307278d6ccf2593dfa6c2e88b2b37 187 Gene3D G3DSA:3.40.630.30 13 179 2.6E-21 T 28-03-2018 CIG75_RS04640 d479d79c4d5da4df7ed0dd3e30a0e167 86 Pfam PF06949 Protein of unknown function (DUF1292) 11 71 5.1E-7 T 28-03-2018 IPR009711 Uncharacterised protein family UPF0473 CIG75_RS04960 1d9d4a48a917808a99dc6724baec1daf 105 Pfam PF05977 Transmembrane secretion effector 7 65 7.3E-6 T 28-03-2018 IPR010290 Transmembrane secretion effector CIG75_RS09630 859fa8cbf00466f167673d9c3279fbd1 284 Pfam PF07307 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 28 222 1.5E-29 T 28-03-2018 IPR009920 Heptaprenyl diphosphate synthase subunit 1 GO:0009234 KEGG: 00900+2.5.1.30|MetaCyc: PWY-5807 CIG75_RS02515 4d27f916cdfd164b82e40ed37e92c0d8 402 Pfam PF07949 YbbR-like protein 329 400 1.1E-6 T 28-03-2018 IPR012505 YbbR-like CIG75_RS02515 4d27f916cdfd164b82e40ed37e92c0d8 402 Pfam PF07949 YbbR-like protein 135 219 8.8E-9 T 28-03-2018 IPR012505 YbbR-like CIG75_RS02515 4d27f916cdfd164b82e40ed37e92c0d8 402 Pfam PF07949 YbbR-like protein 228 306 2.7E-13 T 28-03-2018 IPR012505 YbbR-like CIG75_RS08740 20359232d1538795854aaef613395bbb 157 Pfam PF07486 Cell Wall Hydrolase 26 146 3.7E-11 T 28-03-2018 IPR011105 Cell wall hydrolase, SleB GO:0016787 CIG75_RS18885 a1089f4b6298b1cc3a5f097494d8b475 132 Pfam PF13274 Protein of unknown function (DUF4065) 6 96 5.9E-18 T 28-03-2018 IPR025272 Domain of unknown function DUF4065 CIG75_RS08670 4fc8081f4ae87fbb606f171f360c9bc5 264 SUPERFAMILY SSF56219 41 264 5.76E-38 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CIG75_RS08670 4fc8081f4ae87fbb606f171f360c9bc5 264 Gene3D G3DSA:3.60.10.10 33 262 3.8E-32 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CIG75_RS08670 4fc8081f4ae87fbb606f171f360c9bc5 264 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 47 254 1.0E-12 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CIG75_RS00295 904da267cd62186734323c5da80cdf06 166 Pfam PF14584 Protein of unknown function (DUF4446) 14 161 6.7E-46 T 28-03-2018 IPR027981 Protein of unknown function DUF4446 CIG75_RS07195 e20f65b291b300e99d4d7190371255df 241 Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif 99 148 2.9E-17 T 28-03-2018 IPR011096 FTP domain CIG75_RS04340 21ebb0f2c41d4e7a3a4d9a6f094e0627 314 Pfam PF13349 Putative adhesin 49 311 4.6E-35 T 28-03-2018 IPR025164 Putative adhesin CIG75_RS06280 38a2219c3b405fa995ceba0c7b06df1f 209 Pfam PF09335 SNARE associated Golgi protein 62 173 8.2E-25 T 28-03-2018 IPR032816 SNARE associated Golgi protein CIG75_RS04310 034d1c8440b7715f8af13fffcd8d6137 199 Pfam PF13618 Gluconate 2-dehydrogenase subunit 3 65 175 3.5E-17 T 28-03-2018 IPR027056 Gluconate 2-dehydrogenase subunit 3 KEGG: 00030+1.1.99.3|MetaCyc: PWY-7165 CIG75_RS18455 cc8780fc2ef3caa58b5de4af015e184f 304 Pfam PF04326 Putative DNA-binding domain 150 250 1.5E-15 T 28-03-2018 IPR007421 Schlafen, AAA domain GO:0005524 CIG75_RS06595 336077bd2df6ec93d81a94577e08aa45 414 Pfam PF04235 Protein of unknown function (DUF418) 240 399 6.4E-43 T 28-03-2018 IPR007349 Domain of unknown function DUF418 CIG75_RS12610 5d4b1fa6623158a6f193ba39a3e47881 578 Pfam PF10011 Predicted membrane protein (DUF2254) 56 201 1.3E-17 T 28-03-2018 IPR018723 Protein of unknown function DUF2254, membrane CIG75_RS19895 4a1ad96ed7564d825be2fcefe6e1c46b 153 PIRSF PIRSF010607 1 153 1.1E-55 T 28-03-2018 IPR008463 Transcriptional repressor of class III stress genes GO:0003677|GO:0006355|GO:0006950 CIG75_RS19895 4a1ad96ed7564d825be2fcefe6e1c46b 153 Pfam PF05848 Firmicute transcriptional repressor of class III stress genes (CtsR) 3 150 2.7E-52 T 28-03-2018 IPR008463 Transcriptional repressor of class III stress genes GO:0003677|GO:0006355|GO:0006950 CIG75_RS03955 5d4da0967f67260058b20c15da4f7717 330 Pfam PF01758 Sodium Bile acid symporter family 44 223 8.9E-19 T 28-03-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 CIG75_RS17020 990f97aad9c0e7bee8ec67ebb269d4cb 156 Gene3D G3DSA:2.60.120.380 24 153 2.3E-13 T 28-03-2018 CIG75_RS13185 92e44862b61450c911fdf97728a33cec 92 Pfam PF02325 YGGT family 11 81 1.8E-20 T 28-03-2018 IPR003425 CCB3/YggT GO:0016020 CIG75_RS10330 138a94c097f77c65e2be5fbdf62fa81a 513 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 34 496 1.8E-149 T 28-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 CIG75_RS10330 138a94c097f77c65e2be5fbdf62fa81a 513 PIRSF PIRSF005690 19 511 2.3E-149 T 28-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 CIG75_RS11260 bf0a723bc8a97754bbdd66fd5e6d5392 256 Gene3D G3DSA:2.60.40.1120 14 78 3.4E-4 T 28-03-2018 CIG75_RS09615 66913c072d3a2e237eef385da7b83622 75 Pfam PF04070 Domain of unknown function (DUF378) 6 64 6.0E-27 T 28-03-2018 IPR007211 Protein of unknown function DUF378 CIG75_RS13905 763f791b72a6bb1df83c79c9f8b5ee50 140 Pfam PF03780 Asp23 family, cell envelope-related function 11 114 7.3E-38 T 28-03-2018 IPR005531 Alkaline shock protein Asp23 CIG75_RS15605 3404f41ac437e7a1ae64bf7c3f106d02 189 Gene3D G3DSA:1.20.1260.10 1 184 9.4E-53 T 28-03-2018 IPR012347 Ferritin-related CIG75_RS15605 3404f41ac437e7a1ae64bf7c3f106d02 189 Pfam PF05067 Manganese containing catalase 2 184 9.8E-74 T 28-03-2018 IPR007760 Manganese catalase CIG75_RS15605 3404f41ac437e7a1ae64bf7c3f106d02 189 SUPERFAMILY SSF47240 2 183 9.92E-66 T 28-03-2018 IPR009078 Ferritin-like superfamily CIG75_RS07490 3791fc0d68382a1caeefdd196e08bd0d 83 Pfam PF10737 Spore germination protein GerPC 11 62 5.3E-9 T 28-03-2018 IPR019673 Spore germination protein GerPC CIG75_RS14530 c2ce8c060c48f6662afc3939dd66c7fc 330 Pfam PF12679 ABC-2 family transporter protein 7 328 1.5E-26 T 28-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 CIG75_RS05980 0f3379ffd57caaeee2a49784e60279c8 306 Pfam PF08812 YtxC-like family 70 279 2.0E-44 T 28-03-2018 IPR014199 Sporulation protein YtxC CIG75_RS13000 3f9dd42333b39da924ea19cdca083848 89 Pfam PF10719 Late competence development protein ComFB 6 85 3.6E-21 T 28-03-2018 IPR019657 Late competence development protein ComFB CIG75_RS05540 bb25c49e55db4deb77192691d05c798b 67 Gene3D G3DSA:3.40.50.300 1 65 6.9E-4 T 28-03-2018 CIG75_RS16045 d0be84b853b215f320543843646e3df4 281 Pfam PF09580 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) 19 279 1.9E-7 T 28-03-2018 IPR019076 Sporulation lipoprotein YhcN/YlaJ-like CIG75_RS16045 d0be84b853b215f320543843646e3df4 281 Gene3D G3DSA:3.40.190.10 1 264 5.0E-5 T 28-03-2018 CIG75_RS06750 efda00f4129b5a02f85abf2d94545047 266 Pfam PF12787 EcsC protein family 10 257 1.5E-76 T 28-03-2018 IPR024787 EcsC protein CIG75_RS06750 efda00f4129b5a02f85abf2d94545047 266 ProDom PD038378 ECSC YDBA CC1715 BH1193 ECSC-LIKE ESCC 11 260 2.0E-83 T 28-03-2018 CIG75_RS02840 c1b1fc733c23a1f41624c48c3e998ce5 121 Pfam PF12788 YmaF family 28 116 1.7E-16 T 28-03-2018 IPR024307 YmaF CIG75_RS03710 013f74dedbc3cf48fad6eaec6ef89ff9 325 Pfam PF00953 Glycosyl transferase family 4 76 240 2.8E-35 T 28-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CIG75_RS05100 13039ead5828b2d616f804cdf36b1365 187 Gene3D G3DSA:1.10.287.40 46 148 6.5E-4 T 28-03-2018 CIG75_RS04975 41b341c22625a89e3c8683479c3312a5 214 Pfam PF01027 Inhibitor of apoptosis-promoting Bax1 14 206 1.4E-35 T 28-03-2018 IPR006214 Bax inhibitor 1-related CIG75_RS16725 dbf52f64295ef53b9ed3d22b1270dccd 158 Gene3D G3DSA:3.40.50.150 2 110 3.7E-4 T 28-03-2018 CIG75_RS01325 73c0c8a62836bbfa9f26f260181de7b4 144 Pfam PF03994 Domain of Unknown Function (DUF350) 13 77 2.8E-15 T 28-03-2018 IPR007140 Protein of unknown function DUF350 CIG75_RS01325 73c0c8a62836bbfa9f26f260181de7b4 144 Pfam PF03994 Domain of Unknown Function (DUF350) 89 140 8.9E-12 T 28-03-2018 IPR007140 Protein of unknown function DUF350 CIG75_RS12580 85a716a38e84124b25f26181f33e9300 267 Pfam PF06182 ABC-2 family transporter protein 35 266 5.4E-35 T 28-03-2018 IPR010390 Protein of unknown function DUF990 CIG75_RS18915 d9924146d50f10ddd8f8b15588467e46 194 Pfam PF10076 Uncharacterised protein conserved in bacteria (DUF2313) 3 143 1.4E-21 T 28-03-2018 IPR018755 Bacteriophage Mu-like, Gp48 CIG75_RS03905 8e5c9b0c4a3302505a9e4bd37dc7f2b7 138 Gene3D G3DSA:3.40.1350.10 11 138 1.7E-6 T 28-03-2018 CIG75_RS03320 678c9b09fd044780753556883ddf8c3a 223 Gene3D G3DSA:3.40.630.30 1 164 6.1E-6 T 28-03-2018 CIG75_RS12035 f609639e46829d5fa969eb78ec8ebed2 458 Pfam PF02120 Flagellar hook-length control protein FliK 325 401 7.2E-16 T 28-03-2018 IPR021136 Flagellar hook-length control protein-like, C-terminal CIG75_RS08230 fbeef7b811f4281537ffb8dea2cfd6b6 168 Gene3D G3DSA:1.20.1170.10 1 168 1.1E-4 T 28-03-2018 CIG75_RS17490 befd50cb98b8578afb4f0c3fd227992d 319 Pfam PF10040 CRISPR-associated endoribonuclease Cas6 196 315 9.3E-17 T 28-03-2018 IPR019267 CRISPR-associated protein Cas6, C-terminal CIG75_RS06435 ffe3e6fd195969e151b806b72f1c6043 62 Gene3D G3DSA:1.10.287.950 1 61 9.4E-4 T 28-03-2018 CIG75_RS14300 5394345a9c6b01e79243e499f8d1a199 142 Pfam PF08818 Domain of unknown function (DU1801) 32 137 9.2E-13 T 28-03-2018 IPR014922 Domain of unknown function DUF1801 CIG75_RS14300 5394345a9c6b01e79243e499f8d1a199 142 SUPERFAMILY SSF159888 18 121 4.19E-15 T 28-03-2018 CIG75_RS08565 40d24cbf4425556b7958ac0a84b95760 108 Pfam PF14004 Protein of unknown function (DUF4227) 36 108 3.2E-8 T 28-03-2018 IPR025321 Protein of unknown function DUF4227 CIG75_RS11700 7b96e5431a5f11b725e081767f875d80 74 Pfam PF14035 YlzJ-like protein 2 67 1.2E-17 T 28-03-2018 IPR025619 YlzJ-like protein CIG75_RS01800 7c475497f774ec7123b98c26021c2fc3 292 Pfam PF09580 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) 92 276 3.7E-14 T 28-03-2018 IPR019076 Sporulation lipoprotein YhcN/YlaJ-like CIG75_RS11185 c7b3e60fda7d0a7929fb710a12ad0c07 232 Pfam PF13699 Domain of unknown function (DUF4157) 125 197 2.4E-24 T 28-03-2018 IPR025295 Domain of unknown function DUF4157 CIG75_RS13110 6c1477b7904598d54d2402e8168a90a0 96 Pfam PF13799 Domain of unknown function (DUF4183) 25 91 1.3E-16 T 28-03-2018 IPR025237 Domain of unknown function DUF4183 CIG75_RS04470 829c899b3dd1d535f7c2bc527a024042 277 Gene3D G3DSA:1.10.260.40 54 248 0.0011 T 28-03-2018 CIG75_RS02105 a00e66954ddfd2fd20861729a9c0c280 170 TIGRFAM TIGR04398 SLAP_DUP: SLAP domain 48 168 1.7E-24 T 28-03-2018 IPR030910 SLAP domain, Bacillus-type CIG75_RS11530 273fb5b606e122cc590a04b81bd4c3ac 138 Pfam PF13115 YtkA-like 42 119 6.4E-13 T 28-03-2018 IPR032693 YtkA-like domain CIG75_RS11175 e901cd184220e934e7524bf6aa475f4a 128 Pfam PF14107 Domain of unknown function (DUF4280) 5 122 4.6E-32 T 28-03-2018 IPR025460 Protein of unknown function DUF4280 CIG75_RS09885 50ca2073cdf19678583534f81191c06d 256 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 4 235 6.8E-28 T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CIG75_RS05325 ef06d3b88f791e23e25eef96f5a6c2b7 154 Pfam PF04463 Protein of unknown function (DUF523) 3 145 5.3E-44 T 28-03-2018 IPR007553 Domain of unknown function DUF523 CIG75_RS05835 915719242992ee699c48896e84394a7d 85 Gene3D G3DSA:1.20.1230.10 6 83 4.6E-5 T 28-03-2018 CIG75_RS13265 119fb35ee37d2220da75c0825b376f64 585 Gene3D G3DSA:4.10.940.10 453 562 1.1E-19 T 28-03-2018