locus-tag	class	description
J0J80_RS00010	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
J0J80_RS00015	COG2255	four-way junction helicase activity
J0J80_RS00025	COG0632	four-way junction helicase activity
J0J80_RS00030	COG2116	formate transmembrane transporter activity
J0J80_RS00050	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J0J80_RS00055	COG1621	beta-fructofuranosidase activity
J0J80_RS00060	COG1263	PTS System
J0J80_RS00060	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J0J80_RS00065	COG1609	Transcriptional regulator
J0J80_RS00075	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
J0J80_RS00080	COG0826	peptidase U32
J0J80_RS00085	COG0653	protein targeting
J0J80_RS00115	COG4989	oxidoreductase activity
J0J80_RS00145	COG0733	neurotransmitter:sodium symporter activity
J0J80_RS00155	COG3621	Patatin-like phospholipase
J0J80_RS00195	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
J0J80_RS00205	COG0446	pyridine nucleotide-disulphide oxidoreductase
J0J80_RS00355	COG3328	transposase activity
J0J80_RS00360	COG2826	transposase and inactivated derivatives, IS30 family
J0J80_RS00575	COG0671	phosphoesterase, PA-phosphatase related
J0J80_RS00585	COG3328	transposase activity
J0J80_RS00600	COG0116	Belongs to the methyltransferase superfamily
J0J80_RS00625	COG4677	pectinesterase activity
J0J80_RS00640	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
J0J80_RS00650	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
J0J80_RS00655	COG0211	Belongs to the bacterial ribosomal protein bL27 family
J0J80_RS00665	COG0261	This protein binds to 23S rRNA in the presence of protein L20
J0J80_RS00670	COG0784	Response regulator, receiver
J0J80_RS00670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J0J80_RS00670	COG2198	Histidine kinase
J0J80_RS00670	COG2205	protein histidine kinase activity
J0J80_RS00675	COG1994	Peptidase M50
J0J80_RS00700	COG0367	asparagine synthase
J0J80_RS00710	COG2003	Belongs to the UPF0758 family
J0J80_RS00720	COG0285	dihydrofolate synthase activity
J0J80_RS00745	COG1363	Peptidase, m42
J0J80_RS00750	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
J0J80_RS00755	COG0291	Belongs to the bacterial ribosomal protein bL35 family
J0J80_RS00760	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
J0J80_RS00770	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
J0J80_RS00775	COG1484	DNA-dependent DNA replication
J0J80_RS00780	COG3611	Membrane attachment protein
J0J80_RS00790	COG0237	dephospho-CoA kinase activity
J0J80_RS00795	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
J0J80_RS00810	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J0J80_RS00810	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J0J80_RS00815	COG1408	metallophosphoesterase
J0J80_RS00825	COG2084	Dehydrogenase
J0J80_RS00845	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J0J80_RS00860	COG1263	PTS System
J0J80_RS00860	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J0J80_RS00860	COG2190	(PTS) system
J0J80_RS00865	COG0142	geranyltranstransferase activity
J0J80_RS00870	COG1252	NADH dehydrogenase
J0J80_RS00900	COG1051	belongs to the nudix hydrolase family
J0J80_RS00910	COG0205	6-phosphofructokinase activity
J0J80_RS00915	COG0587	DNA-directed DNA polymerase activity
J0J80_RS00920	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
J0J80_RS00925	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
J0J80_RS00930	COG0827	DNA restriction-modification system
J0J80_RS00935	COG3874	Sporulation protein YtfJ
J0J80_RS00945	COG0367	asparagine synthase
J0J80_RS00955	COG2860	membrane
J0J80_RS00960	COG0488	(ABC) transporter
J0J80_RS00965	COG1362	aminopeptidase activity
J0J80_RS01040	COG0860	N-Acetylmuramoyl-L-alanine amidase
J0J80_RS01040	COG1388	LysM domain
J0J80_RS01045	COG1045	serine acetyltransferase
J0J80_RS01065	COG1098	S1 RNA binding domain
J0J80_RS01070	COG0492	ferredoxin-NADP+ reductase activity
J0J80_RS01075	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
J0J80_RS01080	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
J0J80_RS01090	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
J0J80_RS01100	COG0561	phosphatase activity
J0J80_RS01105	COG0647	UMP catabolic process
J0J80_RS01110	COG4470	Protein conserved in bacteria
J0J80_RS01125	COG0534	Mate efflux family protein
J0J80_RS01130	COG1609	Transcriptional regulator
J0J80_RS01135	COG3842	ATPase activity
J0J80_RS01140	COG2508	Transcriptional regulator
J0J80_RS01150	COG0564	pseudouridine synthase activity
J0J80_RS01155	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
J0J80_RS01160	COG2357	RelA SpoT domain protein
J0J80_RS01180	COG1393	Belongs to the ArsC family
J0J80_RS01185	COG3328	transposase activity
J0J80_RS01195	COG4608	Belongs to the ABC transporter superfamily
J0J80_RS01200	COG0444	Belongs to the ABC transporter superfamily
J0J80_RS01205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J0J80_RS01210	COG0601	transmembrane transport
J0J80_RS01215	COG4166	transmembrane transport
J0J80_RS01230	COG1132	(ABC) transporter
J0J80_RS01235	COG1132	(ABC) transporter
J0J80_RS01245	COG0542	response to heat
J0J80_RS01250	COG0561	phosphatase activity
J0J80_RS01260	COG0495	leucyl-tRNA aminoacylation
J0J80_RS01265	COG1242	4 iron, 4 sulfur cluster binding
J0J80_RS01270	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
J0J80_RS01290	COG0589	response to stress
J0J80_RS01295	COG0149	triose-phosphate isomerase activity
J0J80_RS01300	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
J0J80_RS01305	COG0784	Response regulator, receiver
J0J80_RS01305	COG4191	Histidine kinase
J0J80_RS01325	COG2267	carboxylic ester hydrolase activity
J0J80_RS01345	COG2814	Major facilitator Superfamily
J0J80_RS01350	COG1120	ATPase activity
J0J80_RS01355	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J0J80_RS01360	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J0J80_RS01385	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
J0J80_RS01390	COG1757	Na H antiporter
J0J80_RS01415	COG0531	amino acid
J0J80_RS01425	COG0697	spore germination
J0J80_RS01445	COG0463	Glycosyl transferase, family 2
J0J80_RS01480	COG3328	transposase activity
J0J80_RS01490	COG1408	metallophosphoesterase
J0J80_RS01510	COG0463	Glycosyl transferase, family 2
J0J80_RS01530	COG1216	Glycosyl transferase, family 2
J0J80_RS01535	COG1216	Glycosyl transferase, family 2
J0J80_RS01540	COG0438	transferase activity, transferring glycosyl groups
J0J80_RS01545	COG1215	transferase activity, transferring glycosyl groups
J0J80_RS01555	COG1216	Glycosyl transferase, family 2
J0J80_RS01565	COG1216	Glycosyl transferase, family 2
J0J80_RS01570	COG1216	Glycosyl transferase, family 2
J0J80_RS01570	COG1442	glycosyl transferase family 8
J0J80_RS01575	COG0438	transferase activity, transferring glycosyl groups
J0J80_RS01585	COG0438	transferase activity, transferring glycosyl groups
J0J80_RS01590	COG0438	transferase activity, transferring glycosyl groups
J0J80_RS01595	COG0489	protein tyrosine kinase activity
J0J80_RS01605	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
J0J80_RS01610	COG0110	maltose O-acetyltransferase activity
J0J80_RS01615	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J0J80_RS01645	COG1132	(ABC) transporter
J0J80_RS01650	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J0J80_RS01690	COG1210	Utp--glucose-1-phosphate uridylyltransferase
J0J80_RS01695	COG1316	TRANSCRIPTIONal
J0J80_RS01730	COG3475	LICD family
J0J80_RS01755	COG1216	Glycosyl transferase, family 2
J0J80_RS01785	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
J0J80_RS01790	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J0J80_RS01795	COG0489	protein tyrosine kinase activity
J0J80_RS01825	COG4750	Nucleotidyl transferase
J0J80_RS01830	COG0697	spore germination
J0J80_RS01840	COG0463	Glycosyl transferase, family 2
J0J80_RS01860	COG2089	acid synthase
J0J80_RS01865	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J0J80_RS01885	COG3475	LICD family
J0J80_RS01890	COG1216	Glycosyl transferase, family 2
J0J80_RS01900	COG1216	Glycosyl transferase, family 2
J0J80_RS01905	COG4193	domain, Protein
J0J80_RS01905	COG5263	repeat protein
J0J80_RS01935	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
J0J80_RS01945	COG1316	TRANSCRIPTIONal
J0J80_RS01960	COG1028	Short-chain dehydrogenase reductase Sdr
J0J80_RS01990	COG0756	dUTP diphosphatase activity
J0J80_RS01995	COG0602	queuosine metabolic process
J0J80_RS02005	COG1328	CTP reductase activity
J0J80_RS02010	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
J0J80_RS02010	COG1328	CTP reductase activity
J0J80_RS02020	COG1328	CTP reductase activity
J0J80_RS02020	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
J0J80_RS02025	COG3344	reverse transcriptase
J0J80_RS02050	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J0J80_RS02055	COG1121	(ABC) transporter
J0J80_RS02060	COG0803	Belongs to the bacterial solute-binding protein 9 family
J0J80_RS02080	COG1737	Transcriptional regulator
J0J80_RS02085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J0J80_RS02105	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
J0J80_RS02110	COG1012	belongs to the aldehyde dehydrogenase family
J0J80_RS02145	COG1874	Beta-galactosidase
J0J80_RS02150	COG3328	transposase activity
J0J80_RS02175	COG1253	flavin adenine dinucleotide binding
J0J80_RS02190	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
J0J80_RS02215	COG0402	S-adenosylhomocysteine deaminase activity
J0J80_RS02220	COG2985	domain, Protein
J0J80_RS02225	COG0584	glycerophosphoryl diester phosphodiesterase
J0J80_RS02230	COG1959	2 iron, 2 sulfur cluster binding
J0J80_RS02255	COG1307	EDD domain protein, DegV family
J0J80_RS02270	COG1126	abc transporter atp-binding protein
J0J80_RS02275	COG4215	(ABC) transporter
J0J80_RS02280	COG0765	amino acid transport
J0J80_RS02285	COG1131	(ABC) transporter
J0J80_RS02300	COG2205	protein histidine kinase activity
J0J80_RS02305	COG0745	RESPONSE REGULATOR receiver
J0J80_RS02335	COG0488	(ABC) transporter
J0J80_RS02360	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
J0J80_RS02370	COG2226	methyltransferase
J0J80_RS02390	COG1760	l-serine dehydratase
J0J80_RS02395	COG0556	nucleotide-excision repair
J0J80_RS02400	COG3409	Peptidoglycan-binding domain 1 protein
J0J80_RS02400	COG0793	Belongs to the peptidase S41A family
J0J80_RS02410	COG2177	Part of the ABC transporter FtsEX involved in
J0J80_RS02415	COG2884	Cell division ATP-binding protein ftsE
J0J80_RS02420	COG1854	S-ribosylhomocysteine lyase activity
J0J80_RS02425	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
J0J80_RS02445	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
J0J80_RS02455	COG1105	Belongs to the carbohydrate kinase PfkB family
J0J80_RS02480	COG1739	Uncharacterized protein family UPF0029
J0J80_RS02485	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
J0J80_RS02490	COG1077	Cell shape determining protein MreB Mrl
J0J80_RS02500	COG2385	sporulation resulting in formation of a cellular spore
J0J80_RS02510	COG0355	proton-transporting ATP synthase activity, rotational mechanism
J0J80_RS02515	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
J0J80_RS02525	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
J0J80_RS02535	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
J0J80_RS02540	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
J0J80_RS02560	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
J0J80_RS02565	COG0698	ribose 5-phosphate isomerase
J0J80_RS02580	COG0009	L-threonylcarbamoyladenylate synthase
J0J80_RS02585	COG2890	protein-(glutamine-N5) methyltransferase activity
J0J80_RS02590	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
J0J80_RS02595	COG0305	Participates in initiation and elongation during chromosome replication
J0J80_RS02600	COG0359	binds to the 23S rRNA
J0J80_RS02605	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
J0J80_RS02620	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
J0J80_RS02625	COG0629	single-stranded DNA binding
J0J80_RS02630	COG0360	Binds together with S18 to 16S ribosomal RNA
J0J80_RS02635	COG0012	GTP binding
J0J80_RS02645	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
J0J80_RS02650	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J0J80_RS02655	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J0J80_RS02660	COG0084	hydrolase, TatD family'
J0J80_RS02665	COG4608	Belongs to the ABC transporter superfamily
J0J80_RS02670	COG0444	Belongs to the ABC transporter superfamily
J0J80_RS02675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J0J80_RS02680	COG0601	transmembrane transport
J0J80_RS02685	COG4166	transmembrane transport
J0J80_RS02695	COG3328	transposase activity
J0J80_RS02725	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
J0J80_RS02735	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J0J80_RS02740	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
J0J80_RS02745	COG1774	PSP1 C-terminal conserved region
J0J80_RS02750	COG0470	DNA polymerase III
J0J80_RS02755	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
J0J80_RS02770	COG0101	tRNA pseudouridine synthase activity
J0J80_RS02775	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
J0J80_RS02780	COG1122	ATPase activity
J0J80_RS02785	COG1122	ATPase activity
J0J80_RS02795	COG1132	(ABC) transporter
J0J80_RS02935	COG3328	transposase activity
J0J80_RS02950	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
J0J80_RS02955	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
J0J80_RS02960	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
J0J80_RS02965	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
J0J80_RS02980	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J0J80_RS02985	COG0581	inorganic phosphate transmembrane transporter activity
J0J80_RS02990	COG0573	inorganic phosphate transmembrane transporter activity
J0J80_RS03000	COG5002	protein histidine kinase activity
J0J80_RS03005	COG0745	RESPONSE REGULATOR receiver
J0J80_RS03015	COG0590	tRNA wobble adenosine to inosine editing
J0J80_RS03050	COG1435	thymidine kinase activity
J0J80_RS03055	COG1619	proteins homologs of microcin C7 resistance protein MccF
J0J80_RS03060	COG1473	amidohydrolase
J0J80_RS03065	COG5001	Diguanylate cyclase
J0J80_RS03065	COG3300	MHYT domain
J0J80_RS03070	COG0789	Transcriptional regulator
J0J80_RS03090	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J0J80_RS03095	COG0163	prenyltransferase activity
J0J80_RS03100	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
J0J80_RS03105	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
J0J80_RS03120	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
J0J80_RS03135	COG0281	malic enzyme
J0J80_RS03150	COG0622	Phosphoesterase
J0J80_RS03155	COG0174	glutamine synthetase
J0J80_RS03170	COG0284	orotidine-5'-phosphate decarboxylase activity
J0J80_RS03185	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
J0J80_RS03195	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
J0J80_RS03200	COG0540	Belongs to the ATCase OTCase family
J0J80_RS03210	COG1418	mRNA catabolic process
J0J80_RS03230	COG0706	membrane insertase activity
J0J80_RS03235	COG0706	membrane insertase activity
J0J80_RS03245	COG0426	domain, Protein
J0J80_RS03265	COG1012	belongs to the aldehyde dehydrogenase family
J0J80_RS03265	COG1454	alcohol dehydrogenase
J0J80_RS03275	COG2252	PERMEase
J0J80_RS03290	COG1363	Peptidase, m42
J0J80_RS03295	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J0J80_RS03315	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
J0J80_RS03320	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
J0J80_RS03325	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
J0J80_RS03345	COG1210	Utp--glucose-1-phosphate uridylyltransferase
J0J80_RS03380	COG4464	protein tyrosine phosphatase activity
J0J80_RS03405	COG4607	ABC-type enterochelin transport system periplasmic component
J0J80_RS03410	COG4604	ABC transporter, ATP-binding protein
J0J80_RS03415	COG4605	iron ion homeostasis
J0J80_RS03420	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J0J80_RS03425	COG1917	Cupin 2, conserved barrel domain protein
J0J80_RS03425	COG4977	sequence-specific DNA binding
J0J80_RS03445	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
J0J80_RS03450	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
J0J80_RS03455	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
J0J80_RS03470	COG0534	Mate efflux family protein
J0J80_RS03475	COG1098	S1 RNA binding domain
J0J80_RS03505	COG1575	Belongs to the MenA family. Type 1 subfamily
J0J80_RS03510	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
J0J80_RS03515	COG3956	TIGRFAM MazG family protein
J0J80_RS03520	COG2244	polysaccharide biosynthetic process
J0J80_RS03525	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J0J80_RS03555	COG1846	Transcriptional regulator
J0J80_RS03560	COG3314	Sporulation integral membrane protein YlbJ
J0J80_RS03595	COG3850	Histidine kinase
J0J80_RS03595	COG5002	protein histidine kinase activity
J0J80_RS03665	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
J0J80_RS03670	COG0151	Belongs to the GarS family
J0J80_RS03680	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
J0J80_RS03685	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
J0J80_RS03690	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
J0J80_RS03695	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
J0J80_RS03705	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
J0J80_RS03710	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
J0J80_RS03720	COG0516	GMP reductase activity
J0J80_RS03720	COG0517	IMP dehydrogenase activity
J0J80_RS03725	COG2002	toxin-antitoxin pair type II binding
J0J80_RS03730	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
J0J80_RS03735	COG0193	aminoacyl-tRNA hydrolase activity
J0J80_RS03740	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
J0J80_RS03745	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
J0J80_RS03750	COG2088	sporulation resulting in formation of a cellular spore
J0J80_RS03755	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
J0J80_RS03760	COG4466	Protein conserved in bacteria
J0J80_RS03770	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
J0J80_RS03775	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
J0J80_RS03780	COG1078	dGTPase activity
J0J80_RS03790	COG4844	belongs to the
J0J80_RS03795	COG0280	phosphate acetyltransferase
J0J80_RS03800	COG3773	Cell wall hydrolase
J0J80_RS03810	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
J0J80_RS03825	COG0537	adenosine 5'-monophosphoramidase activity
J0J80_RS03835	COG0142	geranyltranstransferase activity
J0J80_RS03840	COG0561	phosphatase activity
J0J80_RS03845	COG1592	Rubrerythrin
J0J80_RS03850	COG1592	Rubrerythrin
J0J80_RS03855	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
J0J80_RS03860	COG1882	Formate acetyltransferase
J0J80_RS03870	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
J0J80_RS03875	COG2011	ABC-type metal ion transport system permease component
J0J80_RS03880	COG1464	Belongs to the NlpA lipoprotein family
J0J80_RS03890	COG1115	amino acid carrier protein
J0J80_RS03915	COG3546	catalase activity
J0J80_RS03930	COG3546	catalase activity
J0J80_RS03935	COG0659	secondary active sulfate transmembrane transporter activity
J0J80_RS03940	COG0513	Belongs to the DEAD box helicase family
J0J80_RS03945	COG0488	(ABC) transporter
J0J80_RS03965	COG1266	CAAX protease self-immunity
J0J80_RS03975	COG0393	Putative heavy-metal-binding
J0J80_RS03985	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
J0J80_RS03990	COG0217	transcriptional regulatory protein
J0J80_RS04005	COG1131	(ABC) transporter
J0J80_RS04020	COG1979	alcohol dehydrogenase
J0J80_RS04040	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
J0J80_RS04050	COG1408	metallophosphoesterase
J0J80_RS04060	COG1397	ADP-ribosylglycohydrolase
J0J80_RS04065	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J0J80_RS04075	COG1876	peptidase activity
J0J80_RS04085	COG0860	N-Acetylmuramoyl-L-alanine amidase
J0J80_RS04085	COG2247	cell wall binding repeat
J0J80_RS04090	COG1741	Belongs to the pirin family
J0J80_RS04100	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
J0J80_RS04105	COG2610	gluconate transmembrane transporter activity
J0J80_RS04110	COG3620	sequence-specific DNA binding
J0J80_RS04130	COG1408	metallophosphoesterase
J0J80_RS04135	COG1114	Component of the transport system for branched-chain amino acids
J0J80_RS04145	COG0789	Transcriptional regulator
J0J80_RS04145	COG4978	Transcriptional regulator
J0J80_RS04185	COG0588	phosphoglycerate mutase activity
J0J80_RS04190	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
J0J80_RS04195	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
J0J80_RS04205	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
J0J80_RS04205	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
J0J80_RS04210	COG2824	Alkylphosphonate utilization operon protein PhnA
J0J80_RS04235	COG1357	PFAM Pentapeptide repeats (8 copies)
J0J80_RS04240	COG0786	glutamate:sodium symporter activity
J0J80_RS04270	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
J0J80_RS04275	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
J0J80_RS04280	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
J0J80_RS04285	COG0187	DNA topoisomerase II activity
J0J80_RS04290	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
J0J80_RS04295	COG2501	S4 domain
J0J80_RS04300	COG4481	Protein conserved in bacteria
J0J80_RS04305	COG0668	transmembrane transport
J0J80_RS04310	COG1475	DNA binding
J0J80_RS04315	COG1192	Involved in chromosome partitioning
J0J80_RS04335	COG0445	tRNA wobble uridine modification
J0J80_RS04340	COG4152	abc transporter atp-binding protein
J0J80_RS04345	COG1668	transmembrane transport
J0J80_RS04350	COG0592	DNA-directed DNA polymerase activity
J0J80_RS04355	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
J0J80_RS04375	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
J0J80_RS04385	COG0017	Asparaginyl-tRNA synthetase
J0J80_RS04395	COG1523	belongs to the glycosyl hydrolase 13 family
J0J80_RS04405	COG0018	arginyl-trna synthetase
J0J80_RS04465	COG0504	CTP synthase activity
J0J80_RS04470	COG3706	GGDEF domain
J0J80_RS04475	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
J0J80_RS04500	COG0745	RESPONSE REGULATOR receiver
J0J80_RS04505	COG2205	protein histidine kinase activity
J0J80_RS04505	COG2770	Histidine kinase
J0J80_RS04510	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
J0J80_RS04515	COG1592	Rubrerythrin
J0J80_RS04525	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
J0J80_RS04530	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
J0J80_RS04545	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
J0J80_RS04560	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
J0J80_RS04575	COG0366	Alpha amylase catalytic
J0J80_RS04580	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
J0J80_RS04595	COG3706	GGDEF domain
J0J80_RS04595	COG2203	Gaf domain
J0J80_RS04595	COG5001	Diguanylate cyclase
J0J80_RS04595	COG4251	negative regulation of phosphorylation
J0J80_RS04605	COG1595	DNA-templated transcription, initiation
J0J80_RS04615	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
J0J80_RS04620	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
J0J80_RS04635	COG0475	glutathione-regulated potassium exporter activity
J0J80_RS04645	COG1494	fructose-1,6-bisphosphatase
J0J80_RS04675	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
J0J80_RS04695	COG0251	oxidation-reduction process
J0J80_RS04700	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
J0J80_RS04705	COG0215	cysteine-tRNA ligase activity
J0J80_RS04710	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
J0J80_RS04715	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J0J80_RS04725	COG0267	Belongs to the bacterial ribosomal protein bL33 family
J0J80_RS04730	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
J0J80_RS04740	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
J0J80_RS04745	COG0081	regulation of translation
J0J80_RS04750	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
J0J80_RS04755	COG0222	ribosome binding
J0J80_RS04760	COG2813	Specifically methylates the guanine in position
J0J80_RS04765	COG0085	RNA polymerase activity
J0J80_RS04770	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
J0J80_RS04775	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
J0J80_RS04780	COG0049	tRNA binding
J0J80_RS04785	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
J0J80_RS04790	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
J0J80_RS04795	COG0051	transcription antitermination factor activity, RNA binding
J0J80_RS04805	COG0088	Forms part of the polypeptide exit tunnel
J0J80_RS04810	COG0089	rRNA binding
J0J80_RS04815	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
J0J80_RS04820	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
J0J80_RS04825	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
J0J80_RS04830	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
J0J80_RS04835	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
J0J80_RS04865	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
J0J80_RS04870	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
J0J80_RS04880	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
J0J80_RS04885	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
J0J80_RS04900	COG0201	protein transport
J0J80_RS04905	COG0563	adenylate kinase activity
J0J80_RS04910	COG0024	Methionine aminopeptidase
J0J80_RS04920	COG0257	Belongs to the bacterial ribosomal protein bL36 family
J0J80_RS04930	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
J0J80_RS04935	COG0202	RNA polymerase activity
J0J80_RS04945	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
J0J80_RS04955	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J0J80_RS04960	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
J0J80_RS04965	COG1846	Transcriptional regulator
J0J80_RS04970	COG0534	Mate efflux family protein
J0J80_RS04975	COG2608	mercury ion transmembrane transporter activity
J0J80_RS04980	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
J0J80_RS05005	COG2267	carboxylic ester hydrolase activity
J0J80_RS05010	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J0J80_RS05020	COG1181	Belongs to the D-alanine--D-alanine ligase family
J0J80_RS05025	COG0740	serine-type endopeptidase activity
J0J80_RS05035	COG1058	Belongs to the CinA family
J0J80_RS05035	COG1546	Belongs to the CinA family
J0J80_RS05045	COG0149	triose-phosphate isomerase activity
J0J80_RS05060	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
J0J80_RS05065	COG2188	Transcriptional regulator
J0J80_RS05070	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J0J80_RS05090	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
J0J80_RS05105	COG3859	Proton-coupled thiamine transporter YuaJ
J0J80_RS05120	COG0561	phosphatase activity
J0J80_RS05125	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J0J80_RS05130	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
J0J80_RS05135	COG2183	response to ionizing radiation
J0J80_RS05160	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J0J80_RS05165	COG1846	Transcriptional regulator
J0J80_RS05170	COG1686	Belongs to the peptidase S11 family
J0J80_RS05180	COG4106	trans-aconitate 2-methyltransferase activity
J0J80_RS05190	COG1752	Esterase of the alpha-beta hydrolase superfamily
J0J80_RS05195	COG1525	nuclease
J0J80_RS05220	COG0778	Nitroreductase
J0J80_RS05225	COG4894	glucomannan catabolic process
J0J80_RS05235	COG1472	Belongs to the glycosyl hydrolase 3 family
J0J80_RS05250	COG4604	ABC transporter, ATP-binding protein
J0J80_RS05260	COG1881	PFAM PEBP family protein
J0J80_RS05265	COG1428	Deoxynucleoside kinase
J0J80_RS05270	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J0J80_RS05275	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J0J80_RS05285	COG1396	sequence-specific DNA binding
J0J80_RS05295	COG2207	Transcriptional regulator
J0J80_RS05315	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
J0J80_RS05320	COG1328	CTP reductase activity
J0J80_RS05325	COG1114	Component of the transport system for branched-chain amino acids
J0J80_RS05350	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
J0J80_RS05365	COG3328	transposase activity
J0J80_RS05370	COG1288	antiporter activity
J0J80_RS05380	COG0628	permease
J0J80_RS05385	COG0110	maltose O-acetyltransferase activity
J0J80_RS05400	COG3328	transposase activity
J0J80_RS05425	COG1819	glycosyl
J0J80_RS05435	COG2070	2-Nitropropane dioxygenase
J0J80_RS05445	COG0439	Biotin carboxylase
J0J80_RS05450	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
J0J80_RS05455	COG0825	malonyl-CoA metabolic process
J0J80_RS05470	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
J0J80_RS05480	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
J0J80_RS05485	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
J0J80_RS05490	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
J0J80_RS05495	COG0739	heme binding
J0J80_RS05570	COG0802	atpase or kinase
J0J80_RS05575	COG1214	PFAM Peptidase M22, glycoprotease
J0J80_RS05595	COG0488	(ABC) transporter
J0J80_RS05600	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
J0J80_RS05610	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
J0J80_RS05625	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
J0J80_RS05630	COG0459	protein refolding
J0J80_RS05635	COG0736	holo-[acyl-carrier-protein] synthase activity
J0J80_RS05640	COG2155	Conserved Protein
J0J80_RS05645	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
J0J80_RS05650	COG0745	RESPONSE REGULATOR receiver
J0J80_RS05655	COG5002	protein histidine kinase activity
J0J80_RS05660	COG0436	Aminotransferase
J0J80_RS05665	COG3103	Sh3 type 3 domain protein
J0J80_RS05665	COG4991	sh3 domain protein
J0J80_RS05665	COG0860	N-Acetylmuramoyl-L-alanine amidase
J0J80_RS05670	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
J0J80_RS05675	COG2137	regulation of response to DNA damage stimulus
J0J80_RS05680	COG2188	Transcriptional regulator
J0J80_RS05695	COG0366	Alpha amylase catalytic
J0J80_RS05700	COG0739	heme binding
J0J80_RS05705	COG4536	flavin adenine dinucleotide binding
J0J80_RS05715	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
J0J80_RS05720	COG1597	lipid kinase activity
J0J80_RS05730	COG4193	domain, Protein
J0J80_RS05730	COG5263	repeat protein
J0J80_RS05745	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J0J80_RS05750	COG0210	DNA helicase
J0J80_RS05755	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
J0J80_RS05765	COG0784	Response regulator, receiver
J0J80_RS05765	COG2205	protein histidine kinase activity
J0J80_RS05770	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
J0J80_RS05775	COG3583	domain protein
J0J80_RS05780	COG1950	PFAM Membrane protein of
J0J80_RS05795	COG0546	phosphoglycolate phosphatase activity
J0J80_RS05820	COG0391	Required for morphogenesis under gluconeogenic growth conditions
J0J80_RS05825	COG1481	regulation of sporulation
J0J80_RS05840	COG0148	phosphopyruvate hydratase activity
J0J80_RS05845	COG0628	permease
J0J80_RS05850	COG0530	calcium, potassium:sodium antiporter activity
J0J80_RS05860	COG0557	exoribonuclease II activity
J0J80_RS05865	COG2843	Capsule synthesis protein
J0J80_RS05870	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
J0J80_RS05890	COG1696	Membrane protein involved in D-alanine export
J0J80_RS05900	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J0J80_RS05905	COG1116	anion transmembrane transporter activity
J0J80_RS05910	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J0J80_RS05920	COG1175	transmembrane transport
J0J80_RS05925	COG0395	ABC-type sugar transport system, permease component
J0J80_RS05930	COG1653	transport
J0J80_RS05935	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
J0J80_RS05940	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
J0J80_RS05945	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
J0J80_RS05950	COG3328	transposase activity
J0J80_RS05955	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J0J80_RS05965	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
J0J80_RS05970	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J0J80_RS05985	COG1272	protein, Hemolysin III
J0J80_RS05990	COG3681	Belongs to the UPF0597 family
J0J80_RS05995	COG2268	Band 7 protein
J0J80_RS06000	COG1876	peptidase activity
J0J80_RS06015	COG0628	permease
J0J80_RS06025	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J0J80_RS06030	COG2217	Heavy metal translocating P-type atpase
J0J80_RS06040	COG5002	protein histidine kinase activity
J0J80_RS06045	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J0J80_RS06080	COG1937	Protein conserved in bacteria
J0J80_RS06085	COG2217	Heavy metal translocating P-type atpase
J0J80_RS06090	COG2217	Heavy metal translocating P-type atpase
J0J80_RS06100	COG1131	(ABC) transporter
J0J80_RS06120	COG5002	protein histidine kinase activity
J0J80_RS06145	COG0534	Mate efflux family protein
J0J80_RS06185	COG1234	tRNA 3'-trailer cleavage
J0J80_RS06190	COG0346	lactoylglutathione lyase activity
J0J80_RS06205	COG1501	Belongs to the glycosyl hydrolase 31 family
J0J80_RS06210	COG0561	phosphatase activity
J0J80_RS06220	COG2207	Transcriptional regulator
J0J80_RS06225	COG0277	FAD linked oxidase domain protein
J0J80_RS06230	COG0534	Mate efflux family protein
J0J80_RS06235	COG2033	superoxide reductase activity
J0J80_RS06250	COG0748	coenzyme F420 binding
J0J80_RS06260	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
J0J80_RS06270	COG3344	reverse transcriptase
J0J80_RS06280	COG2364	Membrane
J0J80_RS06285	COG2207	Transcriptional regulator
J0J80_RS06290	COG2818	Glycosylase
J0J80_RS06310	COG1136	(ABC) transporter
J0J80_RS06355	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
J0J80_RS06370	COG1187	pseudouridine synthase activity
J0J80_RS06380	COG4807	Protein conserved in bacteria
J0J80_RS06405	COG0019	diaminopimelate decarboxylase activity
J0J80_RS06415	COG1473	amidohydrolase
J0J80_RS06420	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
J0J80_RS06435	COG2171	N-acyltransferase activity
J0J80_RS06440	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
J0J80_RS06455	COG0640	Transcriptional regulator
J0J80_RS06460	COG0730	response to heat
J0J80_RS06465	COG2378	regulation of single-species biofilm formation
J0J80_RS06470	COG1473	amidohydrolase
J0J80_RS06475	COG2723	6-phospho-beta-galactosidase activity
J0J80_RS06480	COG0768	penicillin binding
J0J80_RS06525	COG0732	type I restriction modification DNA specificity domain
J0J80_RS06530	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
J0J80_RS06545	COG2003	Belongs to the UPF0758 family
J0J80_RS06605	COG1136	(ABC) transporter
J0J80_RS06610	COG2003	Belongs to the UPF0758 family
J0J80_RS06760	COG0583	DNA-binding transcription factor activity
J0J80_RS06780	COG0070	glutamate synthase
J0J80_RS06780	COG0067	glutamate synthase
J0J80_RS06780	COG0069	glutamate synthase activity
J0J80_RS06805	COG1533	DNA photolyase activity
J0J80_RS06810	COG3711	transcriptional antiterminator
J0J80_RS06815	COG1263	PTS System
J0J80_RS06815	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J0J80_RS06815	COG2190	(PTS) system
J0J80_RS06820	COG2723	6-phospho-beta-galactosidase activity
J0J80_RS06825	COG1316	TRANSCRIPTIONal
J0J80_RS06830	COG0826	peptidase U32
J0J80_RS06835	COG2323	membrane
J0J80_RS06840	COG0037	tRNA processing
J0J80_RS06860	COG1393	Belongs to the ArsC family
J0J80_RS06865	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J0J80_RS06870	COG3557	Belongs to the UPF0374 family
J0J80_RS06875	COG2309	aminopeptidase activity
J0J80_RS06970	COG1175	transmembrane transport
J0J80_RS06975	COG3833	ABC-type maltose transport systems, permease component
J0J80_RS06980	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
J0J80_RS07015	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J0J80_RS07100	COG3263	regulation of cellular component size
J0J80_RS07105	COG1192	Involved in chromosome partitioning
J0J80_RS07125	COG1011	Hydrolase
J0J80_RS07135	COG0577	efflux transmembrane transporter activity
J0J80_RS07140	COG1136	(ABC) transporter
J0J80_RS07145	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
J0J80_RS07150	COG0583	DNA-binding transcription factor activity
J0J80_RS07155	COG3620	sequence-specific DNA binding
J0J80_RS07160	COG0393	Putative heavy-metal-binding
J0J80_RS07185	COG2207	Transcriptional regulator
J0J80_RS07190	COG0534	Mate efflux family protein
J0J80_RS07205	COG2211	Major facilitator Superfamily
J0J80_RS07210	COG0297	glycogen (starch) synthase activity
J0J80_RS07215	COG0024	Methionine aminopeptidase
J0J80_RS07220	COG3250	beta-galactosidase activity
J0J80_RS07225	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J0J80_RS07235	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J0J80_RS07250	COG1609	Transcriptional regulator
J0J80_RS07255	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
J0J80_RS07260	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
J0J80_RS07265	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J0J80_RS07290	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
J0J80_RS07295	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
J0J80_RS07305	COG1811	Na channel or pump
J0J80_RS07320	COG0006	proline dipeptidase activity
J0J80_RS07335	COG1283	sodium-dependent phosphate transmembrane transporter activity
J0J80_RS07340	COG0396	ATPase activity
J0J80_RS07345	COG0719	Fe-S assembly protein
J0J80_RS07350	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
J0J80_RS07355	COG0822	iron-sulfur transferase activity
J0J80_RS07360	COG0719	Fe-S assembly protein
J0J80_RS07375	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
J0J80_RS07380	COG3377	Domain of unknown function (DUF1805)
J0J80_RS07400	COG0297	glycogen (starch) synthase activity
J0J80_RS07405	COG0058	SHG alpha-glucan phosphorylase activity
J0J80_RS07430	COG1595	DNA-templated transcription, initiation
J0J80_RS07435	COG1403	HNH endonuclease
J0J80_RS07440	COG3328	transposase activity
J0J80_RS07455	COG0659	secondary active sulfate transmembrane transporter activity
J0J80_RS07460	COG1061	Type III restriction enzyme res subunit
J0J80_RS07480	COG0613	PHP domain protein
J0J80_RS07490	COG1592	Rubrerythrin
J0J80_RS07500	COG3328	transposase activity
J0J80_RS07505	COG1823	symporter activity
J0J80_RS07510	COG2340	Cysteine-rich secretory protein family
J0J80_RS07515	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
J0J80_RS07520	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
J0J80_RS07540	COG4667	esterase of the alpha-beta hydrolase superfamily
J0J80_RS07545	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
J0J80_RS07550	COG0242	peptide deformylase activity
J0J80_RS07590	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
J0J80_RS07595	COG2011	ABC-type metal ion transport system permease component
J0J80_RS07600	COG1464	Belongs to the NlpA lipoprotein family
J0J80_RS07605	COG1473	amidohydrolase
J0J80_RS07620	COG2985	domain, Protein
J0J80_RS07625	COG3885	ferrous iron binding
J0J80_RS07625	COG2078	PFAM AMMECR1 domain protein
J0J80_RS07650	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
J0J80_RS07670	COG1609	Transcriptional regulator
J0J80_RS07675	COG1263	PTS System
J0J80_RS07675	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J0J80_RS07680	COG1263	PTS System
J0J80_RS07680	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J0J80_RS07685	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J0J80_RS07690	COG1621	beta-fructofuranosidase activity
J0J80_RS07705	COG3328	transposase activity
J0J80_RS07715	COG0513	Belongs to the DEAD box helicase family
J0J80_RS07720	COG2364	Membrane
J0J80_RS07725	COG1523	belongs to the glycosyl hydrolase 13 family
J0J80_RS07730	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J0J80_RS07735	COG3481	metal-dependent phosphohydrolase, HD sub domain
J0J80_RS07740	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J0J80_RS07765	COG3290	protein histidine kinase activity
J0J80_RS07800	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
J0J80_RS07805	COG0297	glycogen (starch) synthase activity
J0J80_RS07810	COG0302	gtp cyclohydrolase
J0J80_RS07820	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
J0J80_RS07825	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
J0J80_RS07830	COG0457	Tetratricopeptide repeat
J0J80_RS07835	COG2738	Putative neutral zinc metallopeptidase
J0J80_RS07840	COG1595	DNA-templated transcription, initiation
J0J80_RS07850	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J0J80_RS07855	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
J0J80_RS07860	COG0617	tRNA 3'-terminal CCA addition
J0J80_RS07870	COG3935	DnaD domain protein
J0J80_RS07875	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
J0J80_RS07880	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J0J80_RS07880	COG4499	WXG100 protein secretion system (Wss), protein YukC
J0J80_RS07885	COG3331	DNA recombination
J0J80_RS07900	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
J0J80_RS07915	COG1692	metallophosphoesterase
J0J80_RS07920	COG2359	stage V sporulation protein S
J0J80_RS07925	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J0J80_RS07930	COG4550	Control of competence regulator ComK, YlbF/YmcA
J0J80_RS07940	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
J0J80_RS07945	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
J0J80_RS07950	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
J0J80_RS07955	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
J0J80_RS07975	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
J0J80_RS07985	COG3763	UPF0154 protein
J0J80_RS07995	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
J0J80_RS08000	COG0187	DNA topoisomerase II activity
J0J80_RS08005	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
J0J80_RS08020	COG1702	phosphate starvation-inducible protein PhoH
J0J80_RS08025	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
J0J80_RS08030	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
J0J80_RS08035	COG0295	cytidine deaminase activity
J0J80_RS08050	COG1381	Involved in DNA repair and RecF pathway recombination
J0J80_RS08055	COG0423	glycine-tRNA ligase activity
J0J80_RS08060	COG0358	DNA primase activity
J0J80_RS08065	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
J0J80_RS08070	COG2384	SAM-dependent methyltransferase
J0J80_RS08075	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
J0J80_RS08080	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
J0J80_RS08085	COG0072	phenylalanine-tRNA ligase activity
J0J80_RS08085	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J0J80_RS08090	COG1605	Chorismate mutase
J0J80_RS08090	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
J0J80_RS08095	COG1609	Transcriptional regulator
J0J80_RS08110	COG0583	DNA-binding transcription factor activity
J0J80_RS08120	COG1956	GAF domain-containing protein
J0J80_RS08130	COG1104	cysteine desulfurase activity
J0J80_RS08140	COG1012	belongs to the aldehyde dehydrogenase family
J0J80_RS08140	COG1454	alcohol dehydrogenase
J0J80_RS08170	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J0J80_RS08175	COG0779	Required for maturation of 30S ribosomal subunits
J0J80_RS08180	COG0195	Participates in both transcription termination and antitermination
J0J80_RS08185	COG2740	Nucleic-acid-binding protein implicated in transcription termination
J0J80_RS08200	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
J0J80_RS08205	COG1368	sulfuric ester hydrolase activity
J0J80_RS08215	COG0322	excinuclease ABC activity
J0J80_RS08220	COG2197	response regulator
J0J80_RS08240	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
J0J80_RS08250	COG0622	Phosphoesterase
J0J80_RS08285	COG1496	oxidoreductase activity
J0J80_RS08290	COG0569	domain protein
J0J80_RS08295	COG0569	domain protein
J0J80_RS08305	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
J0J80_RS08310	COG0561	phosphatase activity
J0J80_RS08320	COG0242	peptide deformylase activity
J0J80_RS08350	COG0772	Belongs to the SEDS family
J0J80_RS08370	COG4471	UPF0298 protein
J0J80_RS08375	COG0228	four-way junction DNA binding
J0J80_RS08380	COG1837	Belongs to the UPF0109 family
J0J80_RS08420	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
J0J80_RS08425	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
J0J80_RS08440	COG0181	hydroxymethylbilane synthase activity
J0J80_RS08450	COG0113	porphobilinogen synthase activity
J0J80_RS08455	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
J0J80_RS08455	COG1648	precorrin-2 dehydrogenase activity
J0J80_RS08460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J0J80_RS08465	COG0765	amino acid transport
J0J80_RS08470	COG1126	abc transporter atp-binding protein
J0J80_RS08485	COG4753	response regulator
J0J80_RS08485	COG2207	Transcriptional regulator
J0J80_RS08515	COG1846	Transcriptional regulator
J0J80_RS08520	COG0386	Belongs to the glutathione peroxidase family
J0J80_RS08525	COG1132	(ABC) transporter
J0J80_RS08535	COG0596	Alpha beta hydrolase
J0J80_RS08560	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
J0J80_RS08585	COG2723	6-phospho-beta-galactosidase activity
J0J80_RS08590	COG1447	Phosphotransferase system cellobiose-specific component IIA
J0J80_RS08605	COG2723	6-phospho-beta-galactosidase activity
J0J80_RS08610	COG1486	melibiose metabolic process
J0J80_RS08615	COG4086	secreted protein
J0J80_RS08635	COG2720	vancomycin resistance protein
J0J80_RS08645	COG1929	Belongs to the glycerate kinase type-1 family
J0J80_RS08655	COG4260	virion core protein, lumpy skin disease virus
J0J80_RS08665	COG1842	Phage shock protein A
J0J80_RS08680	COG2244	polysaccharide biosynthetic process
J0J80_RS08695	COG1187	pseudouridine synthase activity
J0J80_RS08700	COG0613	PHP domain protein
J0J80_RS08710	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
J0J80_RS08720	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J0J80_RS08725	COG1674	ftsk spoiiie
J0J80_RS08730	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J0J80_RS08755	COG0489	protein tyrosine kinase activity
J0J80_RS08760	COG1323	Belongs to the UPF0348 family
J0J80_RS08765	COG1399	metal-binding, possibly nucleic acid-binding protein
J0J80_RS08770	COG0333	Belongs to the bacterial ribosomal protein bL32 family
J0J80_RS08820	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
J0J80_RS08825	COG0513	Belongs to the DEAD box helicase family
J0J80_RS08830	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
J0J80_RS08840	COG0543	2 iron, 2 sulfur cluster binding
J0J80_RS08845	COG0493	'glutamate synthase
J0J80_RS08845	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
J0J80_RS08855	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
J0J80_RS08860	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
J0J80_RS08865	COG0768	penicillin binding
J0J80_RS08870	COG0267	Belongs to the bacterial ribosomal protein bL33 family
J0J80_RS08880	COG1940	carbohydrate kinase activity
J0J80_RS08885	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J0J80_RS08890	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
J0J80_RS08915	COG4537	Required for transformation and DNA binding
J0J80_RS08920	COG1459	type II secretion system
J0J80_RS08925	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J0J80_RS08940	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
J0J80_RS08960	COG0640	Transcriptional regulator
J0J80_RS08980	COG0004	ammonium transporteR
J0J80_RS08985	COG0658	competence protein
J0J80_RS08985	COG2333	competence protein COMEC
J0J80_RS08990	COG4166	transmembrane transport
J0J80_RS08995	COG0488	(ABC) transporter
J0J80_RS09010	COG1199	ATP-dependent helicase activity
J0J80_RS09010	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
J0J80_RS09020	COG1132	(ABC) transporter
J0J80_RS09025	COG1132	(ABC) transporter
J0J80_RS09030	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J0J80_RS09035	COG2195	Cleaves the N-terminal amino acid of tripeptides
J0J80_RS09045	COG0564	pseudouridine synthase activity
J0J80_RS09075	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
J0J80_RS09095	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J0J80_RS09145	COG0312	modulator of DNA gyrase
J0J80_RS09160	COG4988	ABC transporter
J0J80_RS09165	COG1132	(ABC) transporter
J0J80_RS09175	COG2832	Protein of unknown function (DUF454)
J0J80_RS09200	COG4372	Transposase
J0J80_RS09220	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
J0J80_RS09225	COG3022	response to hydroperoxide
J0J80_RS09250	COG2190	(PTS) system
J0J80_RS09250	COG1263	PTS System
J0J80_RS09250	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J0J80_RS09275	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
J0J80_RS09305	COG1619	proteins homologs of microcin C7 resistance protein MccF
J0J80_RS09320	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
J0J80_RS09320	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
J0J80_RS09325	COG1268	BioY protein
J0J80_RS09350	COG1705	Flagellar rod assembly protein muramidase FlgJ
J0J80_RS09385	COG1061	Type III restriction enzyme res subunit
J0J80_RS09390	COG0494	nUDIX hydrolase
J0J80_RS09405	COG0584	glycerophosphoryl diester phosphodiesterase
J0J80_RS09425	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
J0J80_RS09440	COG1349	DNA-binding transcription factor activity
J0J80_RS09445	COG1105	Belongs to the carbohydrate kinase PfkB family
J0J80_RS09450	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J0J80_RS09450	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J0J80_RS09450	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J0J80_RS09485	COG0038	chloride channel
J0J80_RS09490	COG0708	Exodeoxyribonuclease III
J0J80_RS09495	COG5002	protein histidine kinase activity
J0J80_RS09500	COG0745	RESPONSE REGULATOR receiver
J0J80_RS09545	COG0640	Transcriptional regulator
J0J80_RS09550	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
J0J80_RS09555	COG0534	Mate efflux family protein
J0J80_RS09585	COG0720	synthase
J0J80_RS09590	COG0602	queuosine metabolic process
J0J80_RS09595	COG0302	gtp cyclohydrolase
J0J80_RS09600	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
J0J80_RS09605	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
J0J80_RS09610	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
J0J80_RS09620	COG1621	beta-fructofuranosidase activity
J0J80_RS09625	COG1803	Methylglyoxal synthase
J0J80_RS09635	COG0671	phosphoesterase, PA-phosphatase related
J0J80_RS09650	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
J0J80_RS09665	COG4166	transmembrane transport
J0J80_RS09670	COG0601	transmembrane transport
J0J80_RS09675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J0J80_RS09680	COG0444	Belongs to the ABC transporter superfamily
J0J80_RS09710	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
J0J80_RS09725	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J0J80_RS09730	COG1570	exodeoxyribonuclease VII activity
J0J80_RS09740	COG0142	geranyltranstransferase activity
J0J80_RS09745	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
J0J80_RS09750	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
J0J80_RS09755	COG0497	DNA recombination
J0J80_RS09760	COG0750	zinc metalloprotease
J0J80_RS09765	COG0745	RESPONSE REGULATOR receiver
J0J80_RS09770	COG1649	PFAM Uncharacterised BCR, COG1649
J0J80_RS09780	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J0J80_RS09795	COG0735	belongs to the Fur family
J0J80_RS09800	COG4974	Belongs to the 'phage' integrase family
J0J80_RS09810	COG1827	regulation of RNA biosynthetic process
J0J80_RS09850	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J0J80_RS09855	COG0366	Alpha amylase catalytic
J0J80_RS09860	COG2190	(PTS) system
J0J80_RS09860	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J0J80_RS09860	COG1263	PTS System
J0J80_RS09895	COG0366	Alpha amylase catalytic
J0J80_RS09925	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
J0J80_RS09930	COG3326	Membrane
J0J80_RS09940	COG2827	Endonuclease containing a URI domain
J0J80_RS09950	COG0534	Mate efflux family protein
J0J80_RS09960	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
J0J80_RS09970	COG0737	Belongs to the 5'-nucleotidase family
J0J80_RS09995	COG1757	Na H antiporter
J0J80_RS10055	COG1115	amino acid carrier protein
J0J80_RS10065	COG1307	EDD domain protein, DegV family
J0J80_RS10070	COG1671	Belongs to the UPF0178 family
J0J80_RS10075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J0J80_RS10080	COG4129	membrane
J0J80_RS10095	COG1550	Protein conserved in bacteria
J0J80_RS10100	COG0628	permease
J0J80_RS10110	COG0534	Mate efflux family protein
J0J80_RS10115	COG1522	sequence-specific DNA binding
J0J80_RS10120	COG0436	Aminotransferase
J0J80_RS10125	COG0596	Alpha beta hydrolase
J0J80_RS10140	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J0J80_RS10150	COG4377	Putative membrane peptidase family (DUF2324)
J0J80_RS10155	COG0640	Transcriptional regulator
J0J80_RS10165	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J0J80_RS10200	COG0180	Tryptophanyl-tRNA synthetase
J0J80_RS10215	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J0J80_RS10220	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J0J80_RS10230	COG0473	3-isopropylmalate dehydrogenase activity
J0J80_RS10310	COG4824	toxin secretion phage lysis holin
J0J80_RS10355	COG3328	transposase activity
J0J80_RS10370	COG3328	transposase activity
J0J80_RS10385	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
J0J80_RS10405	COG2826	transposase and inactivated derivatives, IS30 family
J0J80_RS10430	COG5002	protein histidine kinase activity
J0J80_RS10465	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
J0J80_RS10470	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
J0J80_RS10550	COG1196	nuclear chromosome segregation
J0J80_RS10580	COG3597	protein domain associated with
J0J80_RS10585	COG0218	Necessary for normal cell division and for the maintenance of normal septation
J0J80_RS10625	COG1401	restriction endodeoxyribonuclease activity
J0J80_RS10640	COG1061	Type III restriction enzyme res subunit
J0J80_RS10670	COG0534	Mate efflux family protein
J0J80_RS10695	COG1331	Highly conserved protein containing a thioredoxin domain
J0J80_RS10710	COG1028	Short-chain dehydrogenase reductase Sdr
J0J80_RS10715	COG0367	asparagine synthase
J0J80_RS10720	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
J0J80_RS10730	COG0252	asparaginase activity
J0J80_RS10740	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
J0J80_RS10745	COG4120	Belongs to the binding-protein-dependent transport system permease family
J0J80_RS10760	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J0J80_RS10760	COG0723	plastoquinol--plastocyanin reductase activity
J0J80_RS10780	COG0733	neurotransmitter:sodium symporter activity
J0J80_RS10805	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
J0J80_RS10810	COG0010	Belongs to the arginase family
J0J80_RS10815	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
J0J80_RS10820	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
J0J80_RS10825	COG1982	Orn Lys Arg decarboxylase major
J0J80_RS10830	COG3706	GGDEF domain
J0J80_RS10850	COG4974	Belongs to the 'phage' integrase family
J0J80_RS10865	COG1523	belongs to the glycosyl hydrolase 13 family
J0J80_RS10885	COG0438	transferase activity, transferring glycosyl groups
J0J80_RS10890	COG0463	Glycosyl transferase, family 2
J0J80_RS10900	COG0534	Mate efflux family protein
J0J80_RS10905	COG1028	Short-chain dehydrogenase reductase Sdr
J0J80_RS10915	COG0800	Aldolase
J0J80_RS10940	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
J0J80_RS10950	COG4720	Psort location CytoplasmicMembrane, score
J0J80_RS10955	COG2081	HI0933 family
J0J80_RS10990	COG0457	Tetratricopeptide repeat
J0J80_RS10990	COG0463	Glycosyl transferase, family 2
J0J80_RS11020	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
J0J80_RS11025	COG1177	transmembrane transport
J0J80_RS11030	COG1176	ABC-type spermidine putrescine transport system, permease component I
J0J80_RS11035	COG3842	ATPase activity
J0J80_RS11045	COG1217	gtp-binding protein TYPA
J0J80_RS11050	COG1466	dna polymerase III delta subunit
J0J80_RS11055	COG0658	competence protein
J0J80_RS11055	COG2333	competence protein COMEC
J0J80_RS11060	COG1596	polysaccharide export
J0J80_RS11060	COG1555	photosystem II stabilization
J0J80_RS11075	COG0799	negative regulation of ribosome biogenesis
J0J80_RS11080	COG1713	HD superfamily hydrolase involved in NAD metabolism
J0J80_RS11085	COG1534	Rna-binding protein
J0J80_RS11090	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
J0J80_RS11095	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
J0J80_RS11105	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
J0J80_RS11105	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J0J80_RS11110	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
J0J80_RS11115	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
J0J80_RS11120	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J0J80_RS11125	COG0572	uridine kinase
J0J80_RS11130	COG0826	peptidase U32
J0J80_RS11135	COG0826	peptidase U32
J0J80_RS11140	COG4122	O-methyltransferase activity
J0J80_RS11145	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
J0J80_RS11150	COG3906	Belongs to the UPF0473 family
J0J80_RS11165	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
J0J80_RS11175	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
J0J80_RS11180	COG0482	sulfurtransferase activity
J0J80_RS11185	COG1079	Belongs to the binding-protein-dependent transport system permease family
J0J80_RS11190	COG4603	Belongs to the binding-protein-dependent transport system permease family
J0J80_RS11195	COG3845	ABC transporter
J0J80_RS11200	COG1744	ABC transporter substrate-binding protein PnrA-like
J0J80_RS11205	COG1744	ABC transporter substrate-binding protein PnrA-like
J0J80_RS11210	COG1744	ABC transporter substrate-binding protein PnrA-like
J0J80_RS11215	COG1280	lysine exporter protein (LysE YggA)
J0J80_RS11215	COG1674	ftsk spoiiie
J0J80_RS11220	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
J0J80_RS11230	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J0J80_RS11235	COG0527	aspartate kinase activity
J0J80_RS11240	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
J0J80_RS11245	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J0J80_RS11255	COG0726	polysaccharide deacetylase
J0J80_RS11265	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
J0J80_RS11270	COG0196	riboflavin kinase activity
J0J80_RS11280	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J0J80_RS11290	COG0481	GTPase activity
J0J80_RS11305	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
J0J80_RS11315	COG2195	Cleaves the N-terminal amino acid of tripeptides
J0J80_RS11320	COG1983	PspC domain protein
J0J80_RS11330	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
J0J80_RS11335	COG0268	Binds directly to 16S ribosomal RNA
J0J80_RS11370	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
J0J80_RS11375	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J0J80_RS11380	COG1610	YqeY-like protein
J0J80_RS11390	COG2348	transferase activity, transferring amino-acyl groups
J0J80_RS11395	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
J0J80_RS11400	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J0J80_RS11405	COG1385	rRNA (uridine-N3-)-methyltransferase activity
J0J80_RS11410	COG2264	protein methyltransferase activity
J0J80_RS11415	COG0484	heat shock protein binding
J0J80_RS11420	COG0443	Heat shock 70 kDa protein
J0J80_RS11425	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
J0J80_RS11430	COG1420	regulation of RNA biosynthetic process
J0J80_RS11440	COG1126	abc transporter atp-binding protein
J0J80_RS11445	COG0765	amino acid transport
J0J80_RS11455	COG1193	negative regulation of DNA recombination
J0J80_RS11465	COG0457	Tetratricopeptide repeat
J0J80_RS11465	COG0705	Rhomboid family
J0J80_RS11470	COG0564	pseudouridine synthase activity
J0J80_RS11475	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
J0J80_RS11510	COG0762	integral membrane protein
J0J80_RS11515	COG1799	cell septum assembly
J0J80_RS11520	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
J0J80_RS11525	COG1873	PFAM PRC-barrel domain
J0J80_RS11530	COG1191	sigma factor activity
J0J80_RS11535	COG1191	sigma factor activity
J0J80_RS11545	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
J0J80_RS11565	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
J0J80_RS11570	COG0772	Belongs to the SEDS family
J0J80_RS11575	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
J0J80_RS11580	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
J0J80_RS11585	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
J0J80_RS11590	COG0768	penicillin binding
J0J80_RS11595	COG0768	penicillin binding
J0J80_RS11605	COG0275	rRNA processing
J0J80_RS11610	COG0218	Necessary for normal cell division and for the maintenance of normal septation
J0J80_RS11620	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
J0J80_RS11625	COG0544	peptidyl-prolyl cis-trans isomerase activity
J0J80_RS11660	COG1247	-acetyltransferase
J0J80_RS11685	COG3069	C4-dicarboxylate transmembrane transporter activity
J0J80_RS11695	COG0210	DNA helicase
J0J80_RS11715	COG0673	inositol 2-dehydrogenase activity
J0J80_RS11720	COG1114	Component of the transport system for branched-chain amino acids
J0J80_RS11735	COG0475	glutathione-regulated potassium exporter activity
J0J80_RS11755	COG1227	inorganic diphosphatase activity
J0J80_RS11760	COG1164	Oligoendopeptidase f
J0J80_RS11765	COG2271	Major facilitator Superfamily
J0J80_RS11770	COG2267	carboxylic ester hydrolase activity
J0J80_RS11780	COG2176	DNA-directed DNA polymerase activity
J0J80_RS11785	COG0442	prolyl-tRNA aminoacylation
J0J80_RS11790	COG0750	zinc metalloprotease
J0J80_RS11800	COG4589	Belongs to the CDS family
J0J80_RS11805	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
J0J80_RS11830	COG0233	cytoplasmic translational termination
J0J80_RS11835	COG0528	UMP kinase activity
J0J80_RS11840	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
J0J80_RS11845	COG0052	Belongs to the universal ribosomal protein uS2 family
J0J80_RS11855	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J0J80_RS11860	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J0J80_RS11875	COG4974	Belongs to the 'phage' integrase family
J0J80_RS11880	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
J0J80_RS11885	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
J0J80_RS11890	COG0758	DNA mediated transformation
J0J80_RS11895	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
J0J80_RS11915	COG0335	large ribosomal subunit rRNA binding
J0J80_RS11925	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
J0J80_RS11955	COG0742	ribosomal rna small subunit methyltransferase
J0J80_RS11970	COG1785	Belongs to the alkaline phosphatase family
J0J80_RS11975	COG3328	transposase activity
J0J80_RS11985	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
J0J80_RS11990	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
J0J80_RS11995	COG0552	protein localization to endoplasmic reticulum
J0J80_RS12000	COG1196	nuclear chromosome segregation
J0J80_RS12005	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
J0J80_RS12030	COG1012	belongs to the aldehyde dehydrogenase family
J0J80_RS12045	COG0577	efflux transmembrane transporter activity
J0J80_RS12055	COG1136	(ABC) transporter
J0J80_RS12095	COG1115	amino acid carrier protein
J0J80_RS12125	COG1285	pathogenesis
J0J80_RS12145	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
J0J80_RS12150	COG0732	type I restriction modification DNA specificity domain
J0J80_RS12155	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
J0J80_RS12180	COG1263	PTS System
J0J80_RS12180	COG2190	(PTS) system
J0J80_RS12180	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J0J80_RS12280	COG1595	DNA-templated transcription, initiation
J0J80_RS12300	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
J0J80_RS12315	COG0419	ATPase involved in DNA repair
J0J80_RS12320	COG0420	3'-5' exonuclease activity
J0J80_RS12325	COG1609	Transcriptional regulator
J0J80_RS12340	COG0406	alpha-ribazole phosphatase activity
J0J80_RS12365	COG4221	oxidoreductase activity
J0J80_RS12380	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
J0J80_RS12385	COG1461	Dihydroxyacetone kinase
J0J80_RS12390	COG1302	Protein conserved in bacteria
J0J80_RS12395	COG0227	Belongs to the bacterial ribosomal protein bL28 family
J0J80_RS12420	COG1564	THIamine pyrophosphokinase
J0J80_RS12425	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
J0J80_RS12430	COG1162	GTPase activity
J0J80_RS12435	COG0515	serine threonine protein kinase
J0J80_RS12435	COG2815	serine threonine protein kinase
J0J80_RS12440	COG0631	protein serine/threonine phosphatase activity
J0J80_RS12450	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
J0J80_RS12450	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J0J80_RS12455	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J0J80_RS12465	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J0J80_RS12470	COG2996	Protein conserved in bacteria
J0J80_RS12485	COG0426	domain, Protein
J0J80_RS12490	COG0346	lactoylglutathione lyase activity
J0J80_RS12500	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
J0J80_RS12510	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
J0J80_RS12515	COG1758	RNA polymerase activity
J0J80_RS12520	COG0194	GDP metabolic process
J0J80_RS12525	COG1293	RNA-binding protein homologous to eukaryotic snRNP
J0J80_RS12530	COG2720	vancomycin resistance protein
J0J80_RS12540	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
J0J80_RS12555	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
J0J80_RS12560	COG1876	peptidase activity
J0J80_RS12580	COG0772	Belongs to the SEDS family
J0J80_RS12585	COG1074	ATP-dependent DNA helicase activity
J0J80_RS12600	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
J0J80_RS12615	COG1160	GTP binding
J0J80_RS12620	COG2183	response to ionizing radiation
J0J80_RS12620	COG0539	negative regulation of cytoplasmic translation
J0J80_RS12635	COG1141	Ferredoxin
J0J80_RS12640	COG1187	pseudouridine synthase activity
J0J80_RS12645	COG0700	Nucleoside recognition
J0J80_RS12650	COG2715	membrane protein required for spore maturation
J0J80_RS12655	COG1686	Belongs to the peptidase S11 family
J0J80_RS12665	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
J0J80_RS12675	COG0697	spore germination
J0J80_RS12685	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J0J80_RS12700	COG2172	sigma factor antagonist activity
J0J80_RS12710	COG1686	Belongs to the peptidase S11 family
J0J80_RS12745	COG2521	methyltransferase
J0J80_RS12745	COG2136	Putative SAM-dependent methyltransferase
J0J80_RS12750	COG0629	single-stranded DNA binding
J0J80_RS12755	COG0612	Peptidase, M16
J0J80_RS12760	COG0612	Peptidase, M16
J0J80_RS12770	COG0813	purine-nucleoside phosphorylase activity
J0J80_RS12775	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
J0J80_RS12780	COG0628	permease
J0J80_RS12795	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
J0J80_RS12850	COG1216	Glycosyl transferase, family 2
J0J80_RS12860	COG0438	transferase activity, transferring glycosyl groups
J0J80_RS12865	COG1216	Glycosyl transferase, family 2
J0J80_RS12865	COG1442	glycosyl transferase family 8
J0J80_RS12870	COG1216	Glycosyl transferase, family 2
J0J80_RS12870	COG1442	glycosyl transferase family 8
J0J80_RS12880	COG1316	TRANSCRIPTIONal
J0J80_RS12890	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
J0J80_RS12895	COG0124	histidyl-tRNA synthetase
J0J80_RS12905	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J0J80_RS12910	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
J0J80_RS12915	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
J0J80_RS12915	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
J0J80_RS12920	COG2244	polysaccharide biosynthetic process
J0J80_RS12925	COG2323	membrane
J0J80_RS12935	COG1862	Preprotein translocase