locus-tag	class	description
GMBLW1_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GMBLW1_RS00010	COG0592	DNA-directed DNA polymerase activity
GMBLW1_RS00050	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GMBLW1_RS00055	COG3938	Belongs to the proline racemase family
GMBLW1_RS00060	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GMBLW1_RS00075	COG0784	Response regulator, receiver
GMBLW1_RS00075	COG4191	Histidine kinase
GMBLW1_RS00085	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GMBLW1_RS00100	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GMBLW1_RS00105	COG0724	RNA recognition motif
GMBLW1_RS00115	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GMBLW1_RS00120	COG0745	RESPONSE REGULATOR receiver
GMBLW1_RS00140	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GMBLW1_RS00145	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GMBLW1_RS00150	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GMBLW1_RS00155	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GMBLW1_RS00160	COG1028	Short-chain dehydrogenase reductase Sdr
GMBLW1_RS00165	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GMBLW1_RS00180	COG0542	response to heat
GMBLW1_RS00185	COG0542	response to heat
GMBLW1_RS00190	COG1796	DNA polymerase
GMBLW1_RS00190	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GMBLW1_RS00200	COG1475	DNA binding
GMBLW1_RS00220	COG1304	FMN binding
GMBLW1_RS00235	COG2264	protein methyltransferase activity
GMBLW1_RS00270	COG1132	(ABC) transporter
GMBLW1_RS00300	COG1459	type II secretion system
GMBLW1_RS00355	COG0823	Involved in the tonB-independent uptake of proteins
GMBLW1_RS00355	COG4946	Tricorn protease homolog
GMBLW1_RS00355	COG1506	peptidase
GMBLW1_RS00375	COG0072	phenylalanine-tRNA ligase activity
GMBLW1_RS00375	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GMBLW1_RS00380	COG2815	serine threonine protein kinase
GMBLW1_RS00380	COG0515	serine threonine protein kinase
GMBLW1_RS00385	COG0167	dihydroorotate dehydrogenase activity
GMBLW1_RS00395	COG3118	belongs to the thioredoxin family
GMBLW1_RS00470	COG1674	ftsk spoiiie
GMBLW1_RS00495	COG1012	belongs to the aldehyde dehydrogenase family
GMBLW1_RS00500	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GMBLW1_RS00510	COG1215	transferase activity, transferring glycosyl groups
GMBLW1_RS00530	COG0515	serine threonine protein kinase
GMBLW1_RS00530	COG2815	serine threonine protein kinase
GMBLW1_RS00540	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GMBLW1_RS00630	COG0131	Imidazoleglycerol-phosphate dehydratase
GMBLW1_RS00640	COG0673	inositol 2-dehydrogenase activity
GMBLW1_RS00660	COG1218	3'(2'),5'-bisphosphate nucleotidase
GMBLW1_RS00670	COG0028	Belongs to the TPP enzyme family
GMBLW1_RS00700	COG2815	serine threonine protein kinase
GMBLW1_RS00700	COG0515	serine threonine protein kinase
GMBLW1_RS00725	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GMBLW1_RS00750	COG0515	serine threonine protein kinase
GMBLW1_RS00750	COG2815	serine threonine protein kinase
GMBLW1_RS00760	COG0539	negative regulation of cytoplasmic translation
GMBLW1_RS00765	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GMBLW1_RS00775	COG3437	response regulator, receiver
GMBLW1_RS00785	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GMBLW1_RS00810	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GMBLW1_RS00825	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
GMBLW1_RS00825	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GMBLW1_RS00830	COG3201	nicotinamide mononucleotide transporter
GMBLW1_RS00860	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GMBLW1_RS00865	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GMBLW1_RS00870	COG0604	alcohol dehydrogenase
GMBLW1_RS00870	COG3321	synthase
GMBLW1_RS00870	COG1028	Short-chain dehydrogenase reductase Sdr
GMBLW1_RS00875	COG1691	(AIR) carboxylase
GMBLW1_RS00885	COG0443	Heat shock 70 kDa protein
GMBLW1_RS01085	COG3210	domain, Protein
GMBLW1_RS01320	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GMBLW1_RS01325	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GMBLW1_RS01330	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GMBLW1_RS01335	COG2211	Major facilitator Superfamily
GMBLW1_RS01340	COG1022	Amp-dependent synthetase and ligase
GMBLW1_RS01485	COG2815	serine threonine protein kinase
GMBLW1_RS01485	COG0515	serine threonine protein kinase
GMBLW1_RS01500	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GMBLW1_RS01510	COG0673	inositol 2-dehydrogenase activity
GMBLW1_RS01520	COG1063	alcohol dehydrogenase
GMBLW1_RS01525	COG0656	L-ascorbic acid biosynthetic process
GMBLW1_RS01530	COG0166	Belongs to the GPI family
GMBLW1_RS01540	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GMBLW1_RS01545	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GMBLW1_RS01550	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GMBLW1_RS01555	COG0649	NAD binding
GMBLW1_RS01575	COG1034	ATP synthesis coupled electron transport
GMBLW1_RS01580	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GMBLW1_RS01585	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GMBLW1_RS01590	COG0839	Belongs to the complex I subunit 6 family
GMBLW1_RS01595	COG0713	ATP synthesis coupled electron transport
GMBLW1_RS01600	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GMBLW1_RS01610	COG1007	ATP synthesis coupled electron transport
GMBLW1_RS01635	COG1028	Short-chain dehydrogenase reductase Sdr
GMBLW1_RS01690	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GMBLW1_RS01695	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GMBLW1_RS01700	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GMBLW1_RS01780	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GMBLW1_RS01785	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GMBLW1_RS01795	COG3540	Alkaline phosphatase
GMBLW1_RS01815	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GMBLW1_RS01830	COG1902	pentaerythritol trinitrate reductase activity
GMBLW1_RS01855	COG3401	FG-GAP repeat protein
GMBLW1_RS01900	COG3963	phosphatidate phosphatase activity
GMBLW1_RS01935	COG2814	Major facilitator Superfamily
GMBLW1_RS01955	COG0523	cobalamin synthesis protein
GMBLW1_RS01985	COG2319	Wd-40 repeat
GMBLW1_RS01985	COG4249	Peptidase C14 caspase catalytic subunit p20
GMBLW1_RS01995	COG4191	Histidine kinase
GMBLW1_RS02000	COG1648	precorrin-2 dehydrogenase activity
GMBLW1_RS02000	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GMBLW1_RS02005	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GMBLW1_RS02010	COG2146	nitrite reductase [NAD(P)H] activity
GMBLW1_RS02015	COG0243	molybdopterin cofactor binding
GMBLW1_RS02020	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GMBLW1_RS02045	COG1899	peptidyl-lysine modification to peptidyl-hypusine
GMBLW1_RS02055	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GMBLW1_RS02100	COG1131	(ABC) transporter
GMBLW1_RS02145	COG4067	protein conserved in archaea
GMBLW1_RS02145	COG0189	ligase activity
GMBLW1_RS02155	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GMBLW1_RS02160	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GMBLW1_RS02180	COG1131	(ABC) transporter
GMBLW1_RS02195	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GMBLW1_RS02210	COG2815	serine threonine protein kinase
GMBLW1_RS02210	COG0515	serine threonine protein kinase
GMBLW1_RS02215	COG1620	l-lactate permease
GMBLW1_RS02220	COG1979	alcohol dehydrogenase
GMBLW1_RS02230	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GMBLW1_RS02235	COG1674	ftsk spoiiie
GMBLW1_RS02235	COG4980	gas vesicle protein
GMBLW1_RS02255	COG1573	uracil-dna glycosylase
GMBLW1_RS02260	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GMBLW1_RS02270	COG0714	Associated with various cellular activities
GMBLW1_RS02300	COG1984	allophanate hydrolase subunit 2
GMBLW1_RS02305	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GMBLW1_RS02310	COG0673	inositol 2-dehydrogenase activity
GMBLW1_RS02335	COG1045	serine acetyltransferase
GMBLW1_RS02340	COG2815	serine threonine protein kinase
GMBLW1_RS02340	COG0515	serine threonine protein kinase
GMBLW1_RS02360	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GMBLW1_RS02365	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GMBLW1_RS02375	COG2815	serine threonine protein kinase
GMBLW1_RS02375	COG0515	serine threonine protein kinase
GMBLW1_RS02400	COG1166	arginine decarboxylase activity
GMBLW1_RS02455	COG3621	Patatin-like phospholipase
GMBLW1_RS02520	COG1199	ATP-dependent helicase activity
GMBLW1_RS02555	COG0492	ferredoxin-NADP+ reductase activity
GMBLW1_RS02560	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GMBLW1_RS02560	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GMBLW1_RS02565	COG1073	alpha beta
GMBLW1_RS02570	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GMBLW1_RS02575	COG0303	'Molybdopterin
GMBLW1_RS02620	COG2815	serine threonine protein kinase
GMBLW1_RS02620	COG0515	serine threonine protein kinase
GMBLW1_RS02625	COG0515	serine threonine protein kinase
GMBLW1_RS02625	COG2815	serine threonine protein kinase
GMBLW1_RS02640	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GMBLW1_RS02660	COG2037	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT)
GMBLW1_RS02665	COG1216	Glycosyl transferase, family 2
GMBLW1_RS02665	COG0438	transferase activity, transferring glycosyl groups
GMBLW1_RS02710	COG2199	diguanylate cyclase activity
GMBLW1_RS02710	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GMBLW1_RS02720	COG2095	MarC family integral membrane protein
GMBLW1_RS02755	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GMBLW1_RS02760	COG0667	Aldo Keto reductase
GMBLW1_RS02805	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GMBLW1_RS02885	COG0473	3-isopropylmalate dehydrogenase activity
GMBLW1_RS02890	COG0473	3-isopropylmalate dehydrogenase activity
GMBLW1_RS02915	COG3002	Belongs to the UPF0753 family
GMBLW1_RS02920	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GMBLW1_RS02925	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GMBLW1_RS02975	COG1028	Short-chain dehydrogenase reductase Sdr
GMBLW1_RS03015	COG1506	peptidase
GMBLW1_RS03015	COG0823	Involved in the tonB-independent uptake of proteins
GMBLW1_RS03100	COG0501	Belongs to the peptidase M48B family
GMBLW1_RS03115	COG2204	response regulator
GMBLW1_RS03195	COG3842	ATPase activity
GMBLW1_RS03200	COG0195	Participates in both transcription termination and antitermination
GMBLW1_RS03200	COG2251	uridine kinase activity
GMBLW1_RS03205	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GMBLW1_RS03215	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GMBLW1_RS03225	COG0515	serine threonine protein kinase
GMBLW1_RS03225	COG2815	serine threonine protein kinase
GMBLW1_RS03230	COG2211	Major facilitator Superfamily
GMBLW1_RS03240	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GMBLW1_RS03245	COG0156	8-amino-7-oxononanoate synthase activity
GMBLW1_RS03285	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GMBLW1_RS03295	COG0529	Catalyzes the synthesis of activated sulfate
GMBLW1_RS03335	COG0542	response to heat
GMBLW1_RS03350	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GMBLW1_RS03360	COG0515	serine threonine protein kinase
GMBLW1_RS03360	COG2815	serine threonine protein kinase
GMBLW1_RS03365	COG0515	serine threonine protein kinase
GMBLW1_RS03390	COG0515	serine threonine protein kinase
GMBLW1_RS03390	COG2815	serine threonine protein kinase
GMBLW1_RS03395	COG2318	DinB family
GMBLW1_RS03405	COG0424	maF-like protein
GMBLW1_RS03435	COG2860	membrane
GMBLW1_RS03445	COG0095	Lipoate-protein ligase
GMBLW1_RS03475	COG1752	Esterase of the alpha-beta hydrolase superfamily
GMBLW1_RS03485	COG0515	serine threonine protein kinase
GMBLW1_RS03485	COG2815	serine threonine protein kinase
GMBLW1_RS03665	COG0023	Translation Initiation Factor
GMBLW1_RS03720	COG0175	sulfate reduction
GMBLW1_RS03730	COG2046	Belongs to the sulfate adenylyltransferase family
GMBLW1_RS03800	COG0693	protein deglycase activity
GMBLW1_RS03805	COG3118	belongs to the thioredoxin family
GMBLW1_RS03805	COG0457	Tetratricopeptide repeat
GMBLW1_RS03815	COG4968	Prepilin-type N-terminal cleavage methylation domain
GMBLW1_RS03860	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GMBLW1_RS03865	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GMBLW1_RS03895	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GMBLW1_RS03900	COG0823	Involved in the tonB-independent uptake of proteins
GMBLW1_RS03900	COG1506	peptidase
GMBLW1_RS03905	COG1253	flavin adenine dinucleotide binding
GMBLW1_RS03920	COG0515	serine threonine protein kinase
GMBLW1_RS03920	COG2815	serine threonine protein kinase
GMBLW1_RS03970	COG0105	UTP biosynthetic process
GMBLW1_RS03985	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
GMBLW1_RS04030	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GMBLW1_RS04035	COG0515	serine threonine protein kinase
GMBLW1_RS04040	COG1643	Atp-dependent helicase
GMBLW1_RS04045	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GMBLW1_RS04055	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GMBLW1_RS04055	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GMBLW1_RS04075	COG0473	3-isopropylmalate dehydrogenase activity
GMBLW1_RS04135	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GMBLW1_RS04140	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GMBLW1_RS04150	COG0124	histidyl-tRNA synthetase
GMBLW1_RS04180	COG1696	Membrane protein involved in D-alanine export
GMBLW1_RS04190	COG0714	Associated with various cellular activities
GMBLW1_RS04200	COG2815	serine threonine protein kinase
GMBLW1_RS04200	COG0515	serine threonine protein kinase
GMBLW1_RS04255	COG0633	Ferredoxin
GMBLW1_RS04265	COG2815	serine threonine protein kinase
GMBLW1_RS04265	COG0515	serine threonine protein kinase
GMBLW1_RS04270	COG2815	serine threonine protein kinase
GMBLW1_RS04270	COG0515	serine threonine protein kinase
GMBLW1_RS04290	COG4948	Mandelate Racemase Muconate Lactonizing
GMBLW1_RS04295	COG1473	amidohydrolase
GMBLW1_RS04300	COG2815	serine threonine protein kinase
GMBLW1_RS04300	COG0515	serine threonine protein kinase
GMBLW1_RS04305	COG3119	arylsulfatase activity
GMBLW1_RS04345	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GMBLW1_RS04350	COG4974	Belongs to the 'phage' integrase family
GMBLW1_RS04375	COG3869	Catalyzes the specific phosphorylation of arginine residues in
GMBLW1_RS04390	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GMBLW1_RS04405	COG4864	UPF0365 protein
GMBLW1_RS04420	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GMBLW1_RS04505	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GMBLW1_RS04515	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GMBLW1_RS04530	COG0671	phosphoesterase, PA-phosphatase related
GMBLW1_RS04530	COG2453	phosphatase
GMBLW1_RS04550	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GMBLW1_RS04585	COG0473	3-isopropylmalate dehydrogenase activity
GMBLW1_RS04585	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GMBLW1_RS04605	COG2268	Band 7 protein
GMBLW1_RS04625	COG0616	signal peptide processing
GMBLW1_RS04630	COG0720	synthase
GMBLW1_RS04645	COG0243	molybdopterin cofactor binding
GMBLW1_RS04650	COG0515	serine threonine protein kinase
GMBLW1_RS04650	COG2815	serine threonine protein kinase
GMBLW1_RS04655	COG0515	serine threonine protein kinase
GMBLW1_RS04655	COG2815	serine threonine protein kinase
GMBLW1_RS04660	COG0542	response to heat
GMBLW1_RS04705	COG2226	methyltransferase
GMBLW1_RS04710	COG2081	HI0933 family
GMBLW1_RS04725	COG0823	Involved in the tonB-independent uptake of proteins
GMBLW1_RS04740	COG2350	Protein conserved in bacteria
GMBLW1_RS04775	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GMBLW1_RS04795	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GMBLW1_RS04810	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GMBLW1_RS04875	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GMBLW1_RS04875	COG0515	serine threonine protein kinase
GMBLW1_RS04880	COG1966	Carbon starvation protein
GMBLW1_RS04885	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
GMBLW1_RS04905	COG0347	Belongs to the P(II) protein family
GMBLW1_RS04920	COG1136	(ABC) transporter
GMBLW1_RS04920	COG0577	efflux transmembrane transporter activity
GMBLW1_RS04930	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GMBLW1_RS04940	COG3119	arylsulfatase activity
GMBLW1_RS04960	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GMBLW1_RS04970	COG1181	Belongs to the D-alanine--D-alanine ligase family
GMBLW1_RS04975	COG1181	Belongs to the D-alanine--D-alanine ligase family
GMBLW1_RS05005	COG0004	ammonium transporteR
GMBLW1_RS05010	COG2815	serine threonine protein kinase
GMBLW1_RS05010	COG0515	serine threonine protein kinase
GMBLW1_RS05025	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GMBLW1_RS05040	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GMBLW1_RS05045	COG0646	methionine synthase
GMBLW1_RS05045	COG1410	methionine synthase
GMBLW1_RS05050	COG0166	Belongs to the GPI family
GMBLW1_RS05055	COG2832	Protein of unknown function (DUF454)
GMBLW1_RS05135	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GMBLW1_RS05140	COG1846	Transcriptional regulator
GMBLW1_RS05145	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GMBLW1_RS05195	COG0419	ATPase involved in DNA repair
GMBLW1_RS05200	COG0420	3'-5' exonuclease activity
GMBLW1_RS05365	COG5002	protein histidine kinase activity
GMBLW1_RS05375	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GMBLW1_RS05410	COG4555	ABC transporter
GMBLW1_RS05430	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GMBLW1_RS05435	COG4968	Prepilin-type N-terminal cleavage methylation domain
GMBLW1_RS05450	COG2124	cytochrome p450
GMBLW1_RS05455	COG0287	Prephenate dehydrogenase
GMBLW1_RS05460	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GMBLW1_RS05470	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
GMBLW1_RS05515	COG0318	PFAM AMP-dependent synthetase and ligase
GMBLW1_RS05515	COG0204	Acyl-transferase
GMBLW1_RS05530	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GMBLW1_RS05540	COG0586	Pfam SNARE associated Golgi protein
GMBLW1_RS05545	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GMBLW1_RS05545	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GMBLW1_RS05590	COG1518	maintenance of DNA repeat elements
GMBLW1_RS05590	COG1468	defense response to virus
GMBLW1_RS05595	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
GMBLW1_RS05605	COG4336	lyase activity
GMBLW1_RS05615	COG0564	pseudouridine synthase activity
GMBLW1_RS05625	COG4948	Mandelate Racemase Muconate Lactonizing
GMBLW1_RS05650	COG4537	Required for transformation and DNA binding
GMBLW1_RS05675	COG1793	dna ligase
GMBLW1_RS05720	COG0750	zinc metalloprotease
GMBLW1_RS05725	COG0750	zinc metalloprotease
GMBLW1_RS05740	COG0515	serine threonine protein kinase
GMBLW1_RS05745	COG0515	serine threonine protein kinase
GMBLW1_RS05755	COG0181	hydroxymethylbilane synthase activity
GMBLW1_RS05815	COG2204	response regulator
GMBLW1_RS05820	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GMBLW1_RS05830	COG0483	inositol monophosphate 1-phosphatase activity
GMBLW1_RS05835	COG1361	Conserved repeat domain
GMBLW1_RS05840	COG3781	membrane
GMBLW1_RS05995	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
GMBLW1_RS06000	COG0504	CTP synthase activity
GMBLW1_RS06015	COG0515	serine threonine protein kinase
GMBLW1_RS06015	COG2815	serine threonine protein kinase
GMBLW1_RS06040	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GMBLW1_RS06050	COG0515	serine threonine protein kinase
GMBLW1_RS06050	COG2815	serine threonine protein kinase
GMBLW1_RS06090	COG0537	adenosine 5'-monophosphoramidase activity
GMBLW1_RS06130	COG0488	(ABC) transporter
GMBLW1_RS06135	COG0436	Aminotransferase
GMBLW1_RS06270	COG5002	protein histidine kinase activity
GMBLW1_RS06275	COG0745	RESPONSE REGULATOR receiver
GMBLW1_RS06290	COG2084	Dehydrogenase
GMBLW1_RS06310	COG0714	Associated with various cellular activities
GMBLW1_RS06370	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GMBLW1_RS06395	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GMBLW1_RS06400	COG0515	serine threonine protein kinase
GMBLW1_RS06400	COG2815	serine threonine protein kinase
GMBLW1_RS06420	COG1595	DNA-templated transcription, initiation
GMBLW1_RS06435	COG0584	glycerophosphoryl diester phosphodiesterase
GMBLW1_RS06490	COG0438	transferase activity, transferring glycosyl groups
GMBLW1_RS06520	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GMBLW1_RS06540	COG0456	acetyltransferase
GMBLW1_RS06555	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GMBLW1_RS06560	COG0352	thiamine-phosphate diphosphorylase activity
GMBLW1_RS06560	COG0351	phosphomethylpyrimidine kinase
GMBLW1_RS06590	COG0515	serine threonine protein kinase
GMBLW1_RS06625	COG1795	PFAM Formaldehyde-activating enzyme (Fae)
GMBLW1_RS06650	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GMBLW1_RS06655	COG0798	PFAM Bile acid sodium symporter
GMBLW1_RS06670	COG0436	Aminotransferase
GMBLW1_RS06680	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GMBLW1_RS06700	COG0483	inositol monophosphate 1-phosphatase activity
GMBLW1_RS06725	COG3059	membrane
GMBLW1_RS06780	COG2815	serine threonine protein kinase
GMBLW1_RS06780	COG0515	serine threonine protein kinase
GMBLW1_RS06810	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GMBLW1_RS06815	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GMBLW1_RS06820	COG1185	polyribonucleotide nucleotidyltransferase activity
GMBLW1_RS06825	COG4191	Histidine kinase
GMBLW1_RS06890	COG0126	phosphoglycerate kinase activity
GMBLW1_RS06920	COG3069	C4-dicarboxylate transmembrane transporter activity
GMBLW1_RS06945	COG1214	PFAM Peptidase M22, glycoprotease
GMBLW1_RS06950	COG0328	RNA-DNA hybrid ribonuclease activity
GMBLW1_RS06995	COG0430	RNA-3'-phosphate cyclase activity
GMBLW1_RS07000	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GMBLW1_RS07010	COG0726	polysaccharide deacetylase
GMBLW1_RS07020	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GMBLW1_RS07025	COG1872	DUF167
GMBLW1_RS07030	COG0515	serine threonine protein kinase
GMBLW1_RS07030	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GMBLW1_RS07050	COG0463	Glycosyl transferase, family 2
GMBLW1_RS07060	COG0539	negative regulation of cytoplasmic translation
GMBLW1_RS07065	COG0667	Aldo Keto reductase
GMBLW1_RS07070	COG4946	Tricorn protease homolog
GMBLW1_RS07070	COG1506	peptidase
GMBLW1_RS07070	COG0823	Involved in the tonB-independent uptake of proteins
GMBLW1_RS07085	COG0515	serine threonine protein kinase
GMBLW1_RS07085	COG2815	serine threonine protein kinase
GMBLW1_RS07115	COG0515	serine threonine protein kinase
GMBLW1_RS07115	COG2815	serine threonine protein kinase
GMBLW1_RS07120	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GMBLW1_RS07130	COG0646	methionine synthase
GMBLW1_RS07130	COG1410	methionine synthase
GMBLW1_RS07145	COG0521	Mo-molybdopterin cofactor biosynthetic process
GMBLW1_RS07155	COG1252	NADH dehydrogenase
GMBLW1_RS07165	COG1611	Belongs to the LOG family
GMBLW1_RS07200	COG0018	arginyl-trna synthetase
GMBLW1_RS07260	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GMBLW1_RS07270	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GMBLW1_RS07275	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GMBLW1_RS07280	COG0649	NAD binding
GMBLW1_RS07310	COG1942	4-Oxalocrotonate Tautomerase
GMBLW1_RS07335	COG2271	Major facilitator Superfamily
GMBLW1_RS07365	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GMBLW1_RS07390	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GMBLW1_RS07390	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GMBLW1_RS07420	COG0717	Belongs to the dCTP deaminase family
GMBLW1_RS07430	COG1404	Belongs to the peptidase S8 family
GMBLW1_RS07430	COG4935	Belongs to the peptidase S8 family
GMBLW1_RS07435	COG1401	restriction endodeoxyribonuclease activity
GMBLW1_RS07495	COG0564	pseudouridine synthase activity
GMBLW1_RS07500	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GMBLW1_RS07520	COG0202	RNA polymerase activity
GMBLW1_RS07525	COG0343	queuine tRNA-ribosyltransferase activity
GMBLW1_RS07535	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GMBLW1_RS07565	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GMBLW1_RS07575	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GMBLW1_RS07580	COG0459	protein refolding
GMBLW1_RS07600	COG0022	dehydrogenase e1 component
GMBLW1_RS07625	COG1663	tetraacyldisaccharide 4'-kinase activity
GMBLW1_RS07630	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GMBLW1_RS07630	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
GMBLW1_RS07650	COG0438	transferase activity, transferring glycosyl groups
GMBLW1_RS07655	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
GMBLW1_RS07690	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GMBLW1_RS07720	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GMBLW1_RS07760	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GMBLW1_RS07995	COG1331	Highly conserved protein containing a thioredoxin domain
GMBLW1_RS08000	COG2271	Major facilitator Superfamily
GMBLW1_RS08005	COG1058	Belongs to the CinA family
GMBLW1_RS08005	COG1546	Belongs to the CinA family
GMBLW1_RS08010	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
GMBLW1_RS08010	COG0037	tRNA processing
GMBLW1_RS08020	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GMBLW1_RS08025	COG0698	ribose 5-phosphate isomerase
GMBLW1_RS08035	COG0657	acetylesterase activity
GMBLW1_RS08035	COG2755	lipolytic protein G-D-S-L family
GMBLW1_RS08050	COG1668	transmembrane transport
GMBLW1_RS08090	COG3505	Type IV secretory pathway VirD4
GMBLW1_RS08105	COG0515	serine threonine protein kinase
GMBLW1_RS08105	COG2815	serine threonine protein kinase
GMBLW1_RS08125	COG3386	PFAM SMP-30 Gluconolaconase
GMBLW1_RS08160	COG2814	Major facilitator Superfamily
GMBLW1_RS08220	COG2217	Heavy metal translocating P-type atpase
GMBLW1_RS08225	COG1937	Protein conserved in bacteria
GMBLW1_RS08235	COG0113	porphobilinogen synthase activity
GMBLW1_RS08250	COG2815	serine threonine protein kinase
GMBLW1_RS08250	COG0515	serine threonine protein kinase
GMBLW1_RS08255	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GMBLW1_RS08260	COG2201	protein-glutamate methylesterase activity
GMBLW1_RS08275	COG0643	Histidine kinase
GMBLW1_RS08275	COG0784	Response regulator, receiver
GMBLW1_RS08275	COG2198	Histidine kinase
GMBLW1_RS08290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GMBLW1_RS08300	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GMBLW1_RS08305	COG0443	Heat shock 70 kDa protein
GMBLW1_RS08315	COG1162	GTPase activity
GMBLW1_RS08320	COG0793	Belongs to the peptidase S41A family
GMBLW1_RS08335	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GMBLW1_RS08350	COG0297	glycogen (starch) synthase activity
GMBLW1_RS08360	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GMBLW1_RS08365	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GMBLW1_RS08380	COG0071	Belongs to the small heat shock protein (HSP20) family
GMBLW1_RS08390	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GMBLW1_RS08395	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GMBLW1_RS08400	COG1053	succinate dehydrogenase
GMBLW1_RS08460	COG2815	serine threonine protein kinase
GMBLW1_RS08460	COG0515	serine threonine protein kinase
GMBLW1_RS08485	COG0514	ATP-dependent DNA helicase (RecQ)
GMBLW1_RS08490	COG0352	thiamine-phosphate diphosphorylase activity
GMBLW1_RS08505	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GMBLW1_RS08510	COG0187	DNA topoisomerase II activity
GMBLW1_RS08520	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GMBLW1_RS08525	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GMBLW1_RS08530	COG0564	pseudouridine synthase activity
GMBLW1_RS08545	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GMBLW1_RS08550	COG0423	glycine-tRNA ligase activity
GMBLW1_RS08580	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GMBLW1_RS08585	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GMBLW1_RS08585	COG0426	domain, Protein
GMBLW1_RS08610	COG0674	pyruvate-flavodoxin oxidoreductase activity
GMBLW1_RS08610	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GMBLW1_RS08615	COG1013	pyruvate-flavodoxin oxidoreductase activity
GMBLW1_RS08675	COG4221	oxidoreductase activity
GMBLW1_RS08685	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GMBLW1_RS08690	COG2890	protein-(glutamine-N5) methyltransferase activity
GMBLW1_RS08735	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GMBLW1_RS08740	COG3119	arylsulfatase activity
GMBLW1_RS08745	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GMBLW1_RS08750	COG0509	glycine decarboxylation via glycine cleavage system
GMBLW1_RS08755	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GMBLW1_RS08765	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GMBLW1_RS08775	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GMBLW1_RS08780	COG0095	Lipoate-protein ligase
GMBLW1_RS08795	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GMBLW1_RS08800	COG1132	(ABC) transporter
GMBLW1_RS08805	COG0803	Belongs to the bacterial solute-binding protein 9 family
GMBLW1_RS08810	COG1121	(ABC) transporter
GMBLW1_RS08815	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GMBLW1_RS08815	COG1321	iron dependent repressor
GMBLW1_RS08820	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GMBLW1_RS08875	COG0612	Peptidase, M16
GMBLW1_RS08895	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GMBLW1_RS08905	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GMBLW1_RS08915	COG0736	holo-[acyl-carrier-protein] synthase activity
GMBLW1_RS08940	COG0517	IMP dehydrogenase activity
GMBLW1_RS08940	COG0516	GMP reductase activity
GMBLW1_RS08955	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GMBLW1_RS08985	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GMBLW1_RS08995	COG0481	GTPase activity
GMBLW1_RS09000	COG0681	Belongs to the peptidase S26 family
GMBLW1_RS09005	COG0681	Belongs to the peptidase S26 family
GMBLW1_RS09010	COG0824	Thioesterase
GMBLW1_RS09040	COG2271	Major facilitator Superfamily
GMBLW1_RS09125	COG1061	Type III restriction enzyme res subunit
GMBLW1_RS09140	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GMBLW1_RS09155	COG1131	(ABC) transporter
GMBLW1_RS09165	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
GMBLW1_RS09175	COG3684	Belongs to the aldolase LacD family
GMBLW1_RS09190	COG0019	diaminopimelate decarboxylase activity
GMBLW1_RS09195	COG0165	Argininosuccinate lyase
GMBLW1_RS09205	COG5002	protein histidine kinase activity
GMBLW1_RS09210	COG0745	RESPONSE REGULATOR receiver
GMBLW1_RS09215	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GMBLW1_RS09235	COG0823	Involved in the tonB-independent uptake of proteins
GMBLW1_RS09235	COG4946	Tricorn protease homolog
GMBLW1_RS09235	COG1506	peptidase
GMBLW1_RS09280	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GMBLW1_RS09285	COG2239	Acts as a magnesium transporter
GMBLW1_RS09290	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GMBLW1_RS09295	COG1127	ABC transporter
GMBLW1_RS09315	COG5002	protein histidine kinase activity
GMBLW1_RS09325	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GMBLW1_RS09340	COG5002	protein histidine kinase activity
GMBLW1_RS09355	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GMBLW1_RS09375	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GMBLW1_RS09380	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GMBLW1_RS09385	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GMBLW1_RS09405	COG1088	dTDP-glucose 4,6-dehydratase activity
GMBLW1_RS09415	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GMBLW1_RS09425	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GMBLW1_RS09430	COG1774	PSP1 C-terminal conserved region
GMBLW1_RS09465	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GMBLW1_RS09480	COG0250	Participates in transcription elongation, termination and antitermination
GMBLW1_RS09485	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GMBLW1_RS09490	COG0081	regulation of translation
GMBLW1_RS09495	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GMBLW1_RS09500	COG0222	ribosome binding
GMBLW1_RS09505	COG0085	RNA polymerase activity
GMBLW1_RS09510	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GMBLW1_RS09520	COG0049	tRNA binding
GMBLW1_RS09525	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GMBLW1_RS09540	COG0604	alcohol dehydrogenase
GMBLW1_RS09540	COG3321	synthase
GMBLW1_RS09540	COG1028	Short-chain dehydrogenase reductase Sdr
GMBLW1_RS09555	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
GMBLW1_RS09560	COG1074	ATP-dependent DNA helicase activity
GMBLW1_RS09565	COG0673	inositol 2-dehydrogenase activity
GMBLW1_RS09585	COG1515	deoxyribonuclease V activity
GMBLW1_RS09595	COG1543	Belongs to the glycosyl hydrolase 57 family
GMBLW1_RS09610	COG0402	S-adenosylhomocysteine deaminase activity
GMBLW1_RS09640	COG0714	Associated with various cellular activities
GMBLW1_RS09680	COG0640	Transcriptional regulator
GMBLW1_RS09700	COG1028	Short-chain dehydrogenase reductase Sdr
GMBLW1_RS09720	COG0254	rRNA binding
GMBLW1_RS09760	COG0714	Associated with various cellular activities
GMBLW1_RS09815	COG1819	glycosyl
GMBLW1_RS09825	COG2755	lipolytic protein G-D-S-L family
GMBLW1_RS09825	COG0657	acetylesterase activity
GMBLW1_RS09835	COG1028	Short-chain dehydrogenase reductase Sdr
GMBLW1_RS09860	COG0384	phenazine biosynthesis protein PhzF
GMBLW1_RS09870	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GMBLW1_RS09875	COG1363	Peptidase, m42
GMBLW1_RS09885	COG0275	rRNA processing
GMBLW1_RS09900	COG0577	efflux transmembrane transporter activity
GMBLW1_RS09900	COG1136	(ABC) transporter
GMBLW1_RS09905	COG1136	(ABC) transporter
GMBLW1_RS09915	COG1191	sigma factor activity
GMBLW1_RS09925	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GMBLW1_RS09940	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GMBLW1_RS09950	COG0484	heat shock protein binding
GMBLW1_RS09955	COG0594	ribonuclease P activity
GMBLW1_RS09960	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GMBLW1_RS09970	COG0134	indole-3-glycerol-phosphate synthase activity
GMBLW1_RS09980	COG0673	inositol 2-dehydrogenase activity
GMBLW1_RS10005	COG3622	Belongs to the hyi family
GMBLW1_RS10020	COG2814	Major facilitator Superfamily
GMBLW1_RS10025	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GMBLW1_RS10030	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GMBLW1_RS10030	COG0519	Catalyzes the synthesis of GMP from XMP
GMBLW1_RS10035	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GMBLW1_RS10050	COG1970	mechanosensitive ion channel activity
GMBLW1_RS10075	COG2373	Large extracellular alpha-helical protein
GMBLW1_RS10100	COG1187	pseudouridine synthase activity
GMBLW1_RS10105	COG0543	2 iron, 2 sulfur cluster binding
GMBLW1_RS10115	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GMBLW1_RS10120	COG0151	Belongs to the GarS family
GMBLW1_RS10140	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GMBLW1_RS10145	COG3494	Protein of unknown function (DUF1009)
GMBLW1_RS10150	COG2264	protein methyltransferase activity
GMBLW1_RS10155	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GMBLW1_RS10165	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GMBLW1_RS10185	COG0655	NAD(P)H dehydrogenase (quinone) activity
GMBLW1_RS10200	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GMBLW1_RS10210	COG2165	general secretion pathway protein
GMBLW1_RS10250	COG1595	DNA-templated transcription, initiation
GMBLW1_RS10255	COG1028	Short-chain dehydrogenase reductase Sdr
GMBLW1_RS10265	COG1819	glycosyl
GMBLW1_RS10270	COG1309	transcriptional regulator
GMBLW1_RS10300	COG4968	Prepilin-type N-terminal cleavage methylation domain
GMBLW1_RS10305	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GMBLW1_RS10310	COG0419	ATPase involved in DNA repair
GMBLW1_RS10315	COG0420	3'-5' exonuclease activity
GMBLW1_RS10380	COG4974	Belongs to the 'phage' integrase family
GMBLW1_RS10390	COG0483	inositol monophosphate 1-phosphatase activity
GMBLW1_RS10395	COG1132	(ABC) transporter
GMBLW1_RS10405	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GMBLW1_RS10410	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GMBLW1_RS10415	COG0142	geranyltranstransferase activity
GMBLW1_RS10420	COG1722	exodeoxyribonuclease VII activity
GMBLW1_RS10425	COG1570	exodeoxyribonuclease VII activity
GMBLW1_RS10435	COG0686	Belongs to the AlaDH PNT family
GMBLW1_RS10440	COG0667	Aldo Keto reductase
GMBLW1_RS10445	COG0051	transcription antitermination factor activity, RNA binding
GMBLW1_RS10450	COG0088	Forms part of the polypeptide exit tunnel
GMBLW1_RS10455	COG0089	rRNA binding
GMBLW1_RS10460	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GMBLW1_RS10465	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GMBLW1_RS10470	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GMBLW1_RS10475	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GMBLW1_RS10480	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GMBLW1_RS10485	COG0255	Belongs to the universal ribosomal protein uL29 family
GMBLW1_RS10490	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GMBLW1_RS10495	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GMBLW1_RS10500	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GMBLW1_RS10505	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GMBLW1_RS10510	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GMBLW1_RS10515	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GMBLW1_RS10520	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GMBLW1_RS10525	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GMBLW1_RS10530	COG0200	Binds to the 23S rRNA
GMBLW1_RS10535	COG0201	protein transport
GMBLW1_RS10540	COG0563	adenylate kinase activity
GMBLW1_RS10545	COG0024	Methionine aminopeptidase
GMBLW1_RS10555	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GMBLW1_RS10560	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GMBLW1_RS10565	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GMBLW1_RS10570	COG0202	RNA polymerase activity
GMBLW1_RS10575	COG0203	ribosomal protein L17
GMBLW1_RS10635	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GMBLW1_RS10690	COG1562	ergosterol biosynthetic process
GMBLW1_RS10750	COG5492	domain, Protein
GMBLW1_RS10750	COG4932	domain protein
GMBLW1_RS10765	COG0515	serine threonine protein kinase
GMBLW1_RS10770	COG0515	serine threonine protein kinase
GMBLW1_RS10775	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GMBLW1_RS10780	COG0429	hydrolase of the alpha beta-hydrolase fold
GMBLW1_RS10795	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GMBLW1_RS10800	COG0247	lactate metabolic process
GMBLW1_RS10805	COG0277	FAD linked oxidase domain protein
GMBLW1_RS10810	COG0277	FAD linked oxidase domain protein
GMBLW1_RS10815	COG0673	inositol 2-dehydrogenase activity
GMBLW1_RS10830	COG1846	Transcriptional regulator
GMBLW1_RS10845	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GMBLW1_RS10850	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GMBLW1_RS10865	COG2814	Major facilitator Superfamily
GMBLW1_RS10870	COG0824	Thioesterase
GMBLW1_RS10885	COG1136	(ABC) transporter
GMBLW1_RS10890	COG2271	Major facilitator Superfamily
GMBLW1_RS10910	COG1129	ABC transporter
GMBLW1_RS10915	COG1172	Belongs to the binding-protein-dependent transport system permease family
GMBLW1_RS10930	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GMBLW1_RS10935	COG0322	excinuclease ABC activity
GMBLW1_RS10965	COG0437	4 iron, 4 sulfur cluster binding
GMBLW1_RS11010	COG2217	Heavy metal translocating P-type atpase
GMBLW1_RS11030	COG1131	(ABC) transporter
GMBLW1_RS11045	COG0730	response to heat
GMBLW1_RS11055	COG1250	3-hydroxyacyl-CoA dehydrogenase
GMBLW1_RS11055	COG1024	Enoyl-CoA hydratase
GMBLW1_RS11075	COG0673	inositol 2-dehydrogenase activity
GMBLW1_RS11080	COG0297	glycogen (starch) synthase activity
GMBLW1_RS11120	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GMBLW1_RS11160	COG0515	serine threonine protein kinase
GMBLW1_RS11160	COG2815	serine threonine protein kinase
GMBLW1_RS11175	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GMBLW1_RS11175	COG0189	ligase activity
GMBLW1_RS11180	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GMBLW1_RS11180	COG0189	ligase activity
GMBLW1_RS11185	COG1132	(ABC) transporter
GMBLW1_RS11210	COG0347	Belongs to the P(II) protein family
GMBLW1_RS11215	COG1229	Formylmethanofuran dehydrogenase subunit A
GMBLW1_RS11280	COG3604	Transcriptional regulator
GMBLW1_RS11315	COG1959	2 iron, 2 sulfur cluster binding
GMBLW1_RS11350	COG3119	arylsulfatase activity
GMBLW1_RS11430	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GMBLW1_RS11440	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GMBLW1_RS11470	COG1408	metallophosphoesterase
GMBLW1_RS11490	COG0714	Associated with various cellular activities
GMBLW1_RS11495	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
GMBLW1_RS11515	COG2204	response regulator
GMBLW1_RS11520	COG5002	protein histidine kinase activity
GMBLW1_RS11525	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GMBLW1_RS11535	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GMBLW1_RS11550	COG2815	serine threonine protein kinase
GMBLW1_RS11550	COG0515	serine threonine protein kinase
GMBLW1_RS11555	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GMBLW1_RS11565	COG1368	sulfuric ester hydrolase activity
GMBLW1_RS11605	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GMBLW1_RS11625	COG0012	GTP binding
GMBLW1_RS11645	COG4152	abc transporter atp-binding protein
GMBLW1_RS11705	COG2827	Endonuclease containing a URI domain
GMBLW1_RS11715	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GMBLW1_RS11715	COG0758	DNA mediated transformation
GMBLW1_RS11725	COG0673	inositol 2-dehydrogenase activity
GMBLW1_RS11730	COG1560	Kdo2-lipid A biosynthetic process
GMBLW1_RS11740	COG0318	PFAM AMP-dependent synthetase and ligase
GMBLW1_RS11785	COG1530	ribonuclease E activity
GMBLW1_RS11790	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GMBLW1_RS11820	COG0107	imidazoleglycerol-phosphate synthase activity
GMBLW1_RS11835	COG0484	heat shock protein binding
GMBLW1_RS11845	COG0443	Heat shock 70 kDa protein
GMBLW1_RS11855	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
GMBLW1_RS11865	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GMBLW1_RS11875	COG0673	inositol 2-dehydrogenase activity
GMBLW1_RS11880	COG2912	Transglutaminase-like superfamily
GMBLW1_RS11895	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
GMBLW1_RS11900	COG0617	tRNA 3'-terminal CCA addition
GMBLW1_RS11910	COG1104	cysteine desulfurase activity
GMBLW1_RS11945	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GMBLW1_RS12000	COG4712	double-strand break repair protein
GMBLW1_RS12035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GMBLW1_RS12045	COG5002	protein histidine kinase activity
GMBLW1_RS12090	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GMBLW1_RS12100	COG0148	phosphopyruvate hydratase activity
GMBLW1_RS12150	COG0714	Associated with various cellular activities
GMBLW1_RS12170	COG0488	(ABC) transporter
GMBLW1_RS12175	COG0577	efflux transmembrane transporter activity
GMBLW1_RS12175	COG1136	(ABC) transporter
GMBLW1_RS12180	COG0577	efflux transmembrane transporter activity
GMBLW1_RS12200	COG1091	dTDP-4-dehydrorhamnose reductase activity
GMBLW1_RS12215	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GMBLW1_RS12215	COG1918	ferrous iron import across plasma membrane
GMBLW1_RS12235	COG1595	DNA-templated transcription, initiation
GMBLW1_RS12240	COG1716	ATPase activity
GMBLW1_RS12245	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GMBLW1_RS12250	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GMBLW1_RS12255	COG3386	PFAM SMP-30 Gluconolaconase
GMBLW1_RS12275	COG0577	efflux transmembrane transporter activity
GMBLW1_RS12275	COG1136	(ABC) transporter
GMBLW1_RS12295	COG4948	Mandelate Racemase Muconate Lactonizing
GMBLW1_RS12480	COG1061	Type III restriction enzyme res subunit
GMBLW1_RS12565	COG2272	Belongs to the type-B carboxylesterase lipase family
GMBLW1_RS12595	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GMBLW1_RS12600	COG2815	serine threonine protein kinase
GMBLW1_RS12600	COG0515	serine threonine protein kinase
GMBLW1_RS12605	COG0825	malonyl-CoA metabolic process
GMBLW1_RS12635	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GMBLW1_RS12640	COG0701	Predicted permease
GMBLW1_RS12650	COG0310	cobalt ion transport
GMBLW1_RS12655	COG1193	negative regulation of DNA recombination
GMBLW1_RS12660	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GMBLW1_RS12670	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GMBLW1_RS12685	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GMBLW1_RS12690	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GMBLW1_RS12700	COG1073	alpha beta
GMBLW1_RS12720	COG4993	Dehydrogenase
GMBLW1_RS12725	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GMBLW1_RS12730	COG0799	negative regulation of ribosome biogenesis
GMBLW1_RS12735	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GMBLW1_RS12755	COG0330	HflC and HflK could
GMBLW1_RS12765	COG0302	gtp cyclohydrolase
GMBLW1_RS12770	COG0247	lactate metabolic process
GMBLW1_RS12770	COG0277	FAD linked oxidase domain protein
GMBLW1_RS12780	COG0314	molybdopterin synthase activity
GMBLW1_RS12785	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GMBLW1_RS12825	COG0028	Belongs to the TPP enzyme family
GMBLW1_RS12830	COG0587	DNA-directed DNA polymerase activity
GMBLW1_RS12840	COG1846	Transcriptional regulator
GMBLW1_RS12855	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GMBLW1_RS12860	COG0811	peptide transport
GMBLW1_RS12905	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GMBLW1_RS12910	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GMBLW1_RS12935	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GMBLW1_RS12940	COG0713	ATP synthesis coupled electron transport
GMBLW1_RS12945	COG0839	Belongs to the complex I subunit 6 family
GMBLW1_RS12950	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GMBLW1_RS12955	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GMBLW1_RS12960	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
GMBLW1_RS12965	COG0179	Fumarylacetoacetate (FAA) hydrolase
GMBLW1_RS12985	COG0415	Belongs to the DNA photolyase family
GMBLW1_RS13000	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GMBLW1_RS13010	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GMBLW1_RS13015	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GMBLW1_RS13020	COG0783	Belongs to the Dps family
GMBLW1_RS13045	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GMBLW1_RS13050	COG0720	synthase
GMBLW1_RS13055	COG2070	2-Nitropropane dioxygenase
GMBLW1_RS13055	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GMBLW1_RS13060	COG3321	synthase
GMBLW1_RS13060	COG0604	alcohol dehydrogenase
GMBLW1_RS13060	COG0604	alcohol dehydrogenase
GMBLW1_RS13060	COG3321	synthase
GMBLW1_RS13065	COG4221	oxidoreductase activity
GMBLW1_RS13065	COG1028	Short-chain dehydrogenase reductase Sdr
GMBLW1_RS13065	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GMBLW1_RS13065	COG3321	synthase
GMBLW1_RS13070	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GMBLW1_RS13075	COG0596	Alpha beta hydrolase
GMBLW1_RS13080	COG0318	PFAM AMP-dependent synthetase and ligase
GMBLW1_RS13085	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GMBLW1_RS13090	COG0489	protein tyrosine kinase activity
GMBLW1_RS13125	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GMBLW1_RS13145	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GMBLW1_RS13145	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GMBLW1_RS13150	COG0237	dephospho-CoA kinase activity
GMBLW1_RS13155	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GMBLW1_RS13160	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GMBLW1_RS13180	COG0438	transferase activity, transferring glycosyl groups
GMBLW1_RS13180	COG1216	Glycosyl transferase, family 2
GMBLW1_RS13185	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GMBLW1_RS13195	COG0552	protein localization to endoplasmic reticulum
GMBLW1_RS13200	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GMBLW1_RS13210	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GMBLW1_RS13215	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GMBLW1_RS13235	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GMBLW1_RS13270	COG0438	transferase activity, transferring glycosyl groups
GMBLW1_RS13290	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GMBLW1_RS13290	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GMBLW1_RS13300	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GMBLW1_RS13310	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GMBLW1_RS13315	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GMBLW1_RS13320	COG2313	pseudouridylate synthase activity
GMBLW1_RS13325	COG0457	Tetratricopeptide repeat
GMBLW1_RS13325	COG0705	Rhomboid family
GMBLW1_RS13345	COG2962	Rard protein
GMBLW1_RS13360	COG0544	peptidyl-prolyl cis-trans isomerase activity
GMBLW1_RS13365	COG0740	serine-type endopeptidase activity
GMBLW1_RS13370	COG0740	serine-type endopeptidase activity
GMBLW1_RS13385	COG0142	geranyltranstransferase activity
GMBLW1_RS13390	COG0459	protein refolding
GMBLW1_RS13395	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GMBLW1_RS13400	COG0459	protein refolding
GMBLW1_RS13405	COG0484	heat shock protein binding
GMBLW1_RS13410	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GMBLW1_RS13420	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
GMBLW1_RS13440	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GMBLW1_RS13445	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GMBLW1_RS13450	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GMBLW1_RS13465	COG1160	GTP binding
GMBLW1_RS13470	COG1028	Short-chain dehydrogenase reductase Sdr
GMBLW1_RS13495	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
GMBLW1_RS13535	COG0714	Associated with various cellular activities
GMBLW1_RS13560	COG0508	dehydrogenase complex catalyzes the overall conversion of
GMBLW1_RS13565	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GMBLW1_RS13570	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GMBLW1_RS13580	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GMBLW1_RS13590	COG0372	Belongs to the citrate synthase family
GMBLW1_RS13605	COG0640	Transcriptional regulator
GMBLW1_RS13610	COG0505	Belongs to the CarA family
GMBLW1_RS13620	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GMBLW1_RS13640	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GMBLW1_RS13650	COG4191	Histidine kinase
GMBLW1_RS13665	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
GMBLW1_RS13680	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GMBLW1_RS13685	COG1007	ATP synthesis coupled electron transport
GMBLW1_RS13695	COG0084	hydrolase, TatD family'
GMBLW1_RS13700	COG0640	Transcriptional regulator
GMBLW1_RS13720	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
GMBLW1_RS13740	COG4303	Ethanolamine ammonia lyase large subunit
GMBLW1_RS13745	COG4302	ethanolamine ammonia-lyase activity
GMBLW1_RS13750	COG0531	amino acid
GMBLW1_RS13770	COG0405	Gamma-glutamyltransferase
GMBLW1_RS13780	COG0646	methionine synthase
GMBLW1_RS13780	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GMBLW1_RS13790	COG0540	Belongs to the ATCase OTCase family
GMBLW1_RS13795	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
GMBLW1_RS13800	COG1051	belongs to the nudix hydrolase family
GMBLW1_RS13810	COG0442	prolyl-tRNA aminoacylation
GMBLW1_RS13845	COG3552	Protein containing von Willebrand factor type A (VWA) domain
GMBLW1_RS13850	COG0714	Associated with various cellular activities
GMBLW1_RS13860	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GMBLW1_RS13895	COG0585	pseudouridine synthase activity
GMBLW1_RS13915	COG0564	pseudouridine synthase activity
GMBLW1_RS13930	COG0189	ligase activity
GMBLW1_RS13990	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GMBLW1_RS14000	COG0515	serine threonine protein kinase
GMBLW1_RS14000	COG2815	serine threonine protein kinase
GMBLW1_RS14020	COG2135	peptidase activity
GMBLW1_RS14030	COG0544	peptidyl-prolyl cis-trans isomerase activity
GMBLW1_RS14040	COG2382	esterase
GMBLW1_RS14040	COG3507	Belongs to the glycosyl hydrolase 43 family
GMBLW1_RS14040	COG3693	PFAM glycoside hydrolase, family 10
GMBLW1_RS14065	COG1090	epimerase
GMBLW1_RS14070	COG0066	3-isopropylmalate dehydratase activity
GMBLW1_RS14080	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GMBLW1_RS14095	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GMBLW1_RS14105	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GMBLW1_RS14120	COG0366	Alpha amylase catalytic
GMBLW1_RS14135	COG4191	Histidine kinase
GMBLW1_RS14140	COG2204	response regulator
GMBLW1_RS14155	COG3119	arylsulfatase activity
GMBLW1_RS14175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GMBLW1_RS14205	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GMBLW1_RS14225	COG4712	double-strand break repair protein
GMBLW1_RS14230	COG0673	inositol 2-dehydrogenase activity
GMBLW1_RS14235	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GMBLW1_RS14255	COG0745	RESPONSE REGULATOR receiver
GMBLW1_RS14260	COG0704	Plays a role in the regulation of phosphate uptake
GMBLW1_RS14265	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GMBLW1_RS14270	COG5002	protein histidine kinase activity
GMBLW1_RS14275	COG0573	inorganic phosphate transmembrane transporter activity
GMBLW1_RS14280	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GMBLW1_RS14300	COG1482	cell wall glycoprotein biosynthetic process
GMBLW1_RS14305	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GMBLW1_RS14315	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GMBLW1_RS14320	COG1088	dTDP-glucose 4,6-dehydratase activity
GMBLW1_RS14345	COG0673	inositol 2-dehydrogenase activity
GMBLW1_RS14355	COG1477	protein flavinylation
GMBLW1_RS14365	COG0356	it plays a direct role in the translocation of protons across the membrane
GMBLW1_RS14370	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GMBLW1_RS14380	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GMBLW1_RS14385	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GMBLW1_RS14390	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GMBLW1_RS14395	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GMBLW1_RS14400	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GMBLW1_RS14405	COG2183	response to ionizing radiation
GMBLW1_RS14465	COG2608	mercury ion transmembrane transporter activity
GMBLW1_RS14465	COG2217	Heavy metal translocating P-type atpase
GMBLW1_RS14475	COG1028	Short-chain dehydrogenase reductase Sdr
GMBLW1_RS14505	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GMBLW1_RS14540	COG2706	6-phosphogluconolactonase activity
GMBLW1_RS14550	COG1741	Belongs to the pirin family
GMBLW1_RS14560	COG1335	isochorismatase
GMBLW1_RS14565	COG1733	regulation of RNA biosynthetic process
GMBLW1_RS14580	COG0622	Phosphoesterase
GMBLW1_RS14585	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GMBLW1_RS14630	COG2308	Evidence 4 Homologs of previously reported genes of
GMBLW1_RS14630	COG2307	Protein conserved in bacteria
GMBLW1_RS14635	COG1305	Transglutaminase-like
GMBLW1_RS14685	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GMBLW1_RS14730	COG4585	Histidine kinase
GMBLW1_RS14735	COG2197	response regulator
GMBLW1_RS14820	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
GMBLW1_RS14825	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GMBLW1_RS14830	COG3119	arylsulfatase activity
GMBLW1_RS14850	COG1335	isochorismatase
GMBLW1_RS14875	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GMBLW1_RS14890	COG0438	transferase activity, transferring glycosyl groups
GMBLW1_RS14945	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GMBLW1_RS14965	COG0116	Belongs to the methyltransferase superfamily
GMBLW1_RS14965	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GMBLW1_RS14980	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
GMBLW1_RS14995	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GMBLW1_RS15005	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GMBLW1_RS15010	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GMBLW1_RS15020	COG1297	OPT oligopeptide transporter protein
GMBLW1_RS15045	COG1921	L-seryl-tRNASec selenium transferase activity
GMBLW1_RS15055	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GMBLW1_RS15065	COG1940	carbohydrate kinase activity
GMBLW1_RS15070	COG4399	Belongs to the UPF0754 family
GMBLW1_RS15075	COG0135	phosphoribosylanthranilate isomerase activity
GMBLW1_RS15080	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
GMBLW1_RS15085	COG0307	riboflavin synthase, alpha
GMBLW1_RS15090	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GMBLW1_RS15095	COG2975	iron-sulfur cluster assembly
GMBLW1_RS15100	COG0443	Heat shock 70 kDa protein
GMBLW1_RS15105	COG0710	3-dehydroquinate dehydratase activity
GMBLW1_RS15125	COG0129	dihydroxy-acid dehydratase activity
GMBLW1_RS15180	COG3119	arylsulfatase activity
GMBLW1_RS15190	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GMBLW1_RS15200	COG0275	rRNA processing
GMBLW1_RS15210	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GMBLW1_RS15215	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GMBLW1_RS15220	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GMBLW1_RS15250	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GMBLW1_RS15250	COG0706	membrane insertase activity
GMBLW1_RS15255	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GMBLW1_RS15280	COG0174	glutamine synthetase
GMBLW1_RS15295	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GMBLW1_RS15300	COG0052	Belongs to the universal ribosomal protein uS2 family
GMBLW1_RS15310	COG0326	Molecular chaperone. Has ATPase activity
GMBLW1_RS15325	COG2815	serine threonine protein kinase
GMBLW1_RS15325	COG0515	serine threonine protein kinase
GMBLW1_RS15340	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GMBLW1_RS15340	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GMBLW1_RS15350	COG3875	lactate racemase activity
GMBLW1_RS15360	COG0246	Mannitol dehydrogenase
GMBLW1_RS15375	COG1408	metallophosphoesterase
GMBLW1_RS15385	COG1136	(ABC) transporter
GMBLW1_RS15390	COG0577	efflux transmembrane transporter activity
GMBLW1_RS15390	COG1136	(ABC) transporter
GMBLW1_RS15400	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GMBLW1_RS15405	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GMBLW1_RS15415	COG0515	serine threonine protein kinase
GMBLW1_RS15415	COG2815	serine threonine protein kinase
GMBLW1_RS15425	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GMBLW1_RS15435	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GMBLW1_RS15440	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GMBLW1_RS15445	COG2030	dehydratase
GMBLW1_RS15450	COG0463	Glycosyl transferase, family 2
GMBLW1_RS15475	COG0495	leucyl-tRNA aminoacylation
GMBLW1_RS15490	COG1657	PFAM Prenyltransferase squalene oxidase
GMBLW1_RS15555	COG3622	Belongs to the hyi family
GMBLW1_RS15565	COG0159	tryptophan synthase activity
GMBLW1_RS15570	COG0133	tryptophan synthase activity
GMBLW1_RS15575	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GMBLW1_RS15580	COG2205	protein histidine kinase activity
GMBLW1_RS15600	COG4968	Prepilin-type N-terminal cleavage methylation domain
GMBLW1_RS15685	COG0666	response to abiotic stimulus
GMBLW1_RS15695	COG3293	Transposase
GMBLW1_RS15755	COG2189	Belongs to the N(4) N(6)-methyltransferase family
GMBLW1_RS15770	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GMBLW1_RS15775	COG2963	transposase activity
GMBLW1_RS15905	COG4977	sequence-specific DNA binding
GMBLW1_RS15915	COG0574	Belongs to the PEP-utilizing enzyme family
GMBLW1_RS15915	COG3848	Pyruvate phosphate dikinase
GMBLW1_RS15935	COG2719	SpoVR family
GMBLW1_RS15940	COG2718	Belongs to the UPF0229 family
GMBLW1_RS15945	COG2766	serine protein kinase
GMBLW1_RS15995	COG0235	Class ii aldolase
GMBLW1_RS16015	COG3852	Histidine kinase
GMBLW1_RS16020	COG2204	response regulator
GMBLW1_RS16055	COG1760	l-serine dehydratase
GMBLW1_RS16085	COG0842	Transport permease protein
GMBLW1_RS16085	COG1129	ABC transporter
GMBLW1_RS16105	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GMBLW1_RS16115	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GMBLW1_RS16155	COG1028	Short-chain dehydrogenase reductase Sdr
GMBLW1_RS16185	COG0515	serine threonine protein kinase
GMBLW1_RS16185	COG2815	serine threonine protein kinase
GMBLW1_RS16225	COG4948	Mandelate Racemase Muconate Lactonizing
GMBLW1_RS16255	COG3258	Cytochrome c
GMBLW1_RS16260	COG2226	methyltransferase
GMBLW1_RS16275	COG3119	arylsulfatase activity
GMBLW1_RS16290	COG1309	transcriptional regulator
GMBLW1_RS16305	COG1597	lipid kinase activity
GMBLW1_RS16310	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GMBLW1_RS16315	COG1233	COG1233 Phytoene dehydrogenase and related
GMBLW1_RS16320	COG1562	ergosterol biosynthetic process
GMBLW1_RS16325	COG1562	ergosterol biosynthetic process
GMBLW1_RS16330	COG1606	tRNA processing
GMBLW1_RS16340	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GMBLW1_RS16360	COG0497	DNA recombination
GMBLW1_RS16390	COG1968	undecaprenyl-diphosphatase activity
GMBLW1_RS16420	COG0714	Associated with various cellular activities
GMBLW1_RS16460	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GMBLW1_RS16470	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GMBLW1_RS16505	COG2815	serine threonine protein kinase
GMBLW1_RS16505	COG0515	serine threonine protein kinase
GMBLW1_RS16520	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GMBLW1_RS16530	COG3481	metal-dependent phosphohydrolase, HD sub domain
GMBLW1_RS16535	COG0557	exoribonuclease II activity
GMBLW1_RS16550	COG4260	virion core protein, lumpy skin disease virus
GMBLW1_RS16565	COG0805	protein transport
GMBLW1_RS16585	COG2721	sulfolactate sulfo-lyase activity
GMBLW1_RS16590	COG0574	Belongs to the PEP-utilizing enzyme family
GMBLW1_RS16590	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GMBLW1_RS16595	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GMBLW1_RS16600	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GMBLW1_RS16610	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GMBLW1_RS16630	COG1012	belongs to the aldehyde dehydrogenase family
GMBLW1_RS16650	COG0793	Belongs to the peptidase S41A family
GMBLW1_RS16680	COG0571	ribonuclease III activity
GMBLW1_RS16685	COG0746	molybdenum cofactor guanylyltransferase activity
GMBLW1_RS16745	COG4712	double-strand break repair protein
GMBLW1_RS16800	COG2189	Belongs to the N(4) N(6)-methyltransferase family
GMBLW1_RS17020	COG3119	arylsulfatase activity
GMBLW1_RS17045	COG1518	maintenance of DNA repeat elements
GMBLW1_RS17050	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
GMBLW1_RS17065	COG0585	pseudouridine synthase activity
GMBLW1_RS17075	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GMBLW1_RS17095	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
GMBLW1_RS17120	COG3386	PFAM SMP-30 Gluconolaconase
GMBLW1_RS17125	COG0515	serine threonine protein kinase
GMBLW1_RS17125	COG2815	serine threonine protein kinase
GMBLW1_RS17140	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GMBLW1_RS17160	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GMBLW1_RS17180	COG2022	thiamine diphosphate biosynthetic process
GMBLW1_RS17185	COG0363	glucosamine-6-phosphate deaminase activity
GMBLW1_RS17220	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GMBLW1_RS17220	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GMBLW1_RS17225	COG0579	oxidoreductase
GMBLW1_RS17240	COG2815	serine threonine protein kinase
GMBLW1_RS17240	COG0515	serine threonine protein kinase
GMBLW1_RS17265	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GMBLW1_RS17295	COG0488	(ABC) transporter
GMBLW1_RS17330	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GMBLW1_RS17335	COG0450	alkyl hydroperoxide reductase
GMBLW1_RS17345	COG2205	protein histidine kinase activity
GMBLW1_RS17350	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
GMBLW1_RS17355	COG4251	negative regulation of phosphorylation
GMBLW1_RS17365	COG2201	protein-glutamate methylesterase activity
GMBLW1_RS17405	COG0714	Associated with various cellular activities
GMBLW1_RS17425	COG2076	Multidrug Resistance protein
GMBLW1_RS17435	COG1858	cytochrome C peroxidase
GMBLW1_RS17440	COG1301	dicarboxylic acid transport
GMBLW1_RS17450	COG0564	pseudouridine synthase activity
GMBLW1_RS17455	COG2319	Wd-40 repeat
GMBLW1_RS17455	COG5635	Nacht domain
GMBLW1_RS17460	COG0523	cobalamin synthesis protein
GMBLW1_RS17515	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GMBLW1_RS17530	COG1446	asparaginase
GMBLW1_RS17545	COG0583	DNA-binding transcription factor activity
GMBLW1_RS17550	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
GMBLW1_RS17555	COG0525	valine-tRNA ligase activity
GMBLW1_RS17560	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GMBLW1_RS17565	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GMBLW1_RS17595	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GMBLW1_RS17630	COG0154	amidase activity
GMBLW1_RS17645	COG0515	serine threonine protein kinase
GMBLW1_RS17645	COG2815	serine threonine protein kinase
GMBLW1_RS17665	COG0300	oxidoreductase activity
GMBLW1_RS17700	COG0714	Associated with various cellular activities
GMBLW1_RS17730	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GMBLW1_RS17755	COG1131	(ABC) transporter
GMBLW1_RS17760	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GMBLW1_RS17780	COG4968	Prepilin-type N-terminal cleavage methylation domain
GMBLW1_RS17820	COG1137	ATPase activity
GMBLW1_RS17830	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GMBLW1_RS17835	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GMBLW1_RS17840	COG0693	protein deglycase activity
GMBLW1_RS17845	COG2115	Belongs to the xylose isomerase family
GMBLW1_RS17855	COG4946	Tricorn protease homolog
GMBLW1_RS17855	COG0793	Belongs to the peptidase S41A family
GMBLW1_RS17880	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GMBLW1_RS17900	COG1561	YicC-like family, N-terminal region
GMBLW1_RS17910	COG0149	triose-phosphate isomerase activity
GMBLW1_RS17915	COG1605	Chorismate mutase
GMBLW1_RS17915	COG0077	Prephenate dehydratase
GMBLW1_RS17920	COG0443	Heat shock 70 kDa protein
GMBLW1_RS17930	COG0205	6-phosphofructokinase activity
GMBLW1_RS17940	COG0405	Gamma-glutamyltransferase
GMBLW1_RS17945	COG1692	metallophosphoesterase
GMBLW1_RS17950	COG1418	mRNA catabolic process
GMBLW1_RS17960	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GMBLW1_RS17965	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GMBLW1_RS17970	COG1216	Glycosyl transferase, family 2
GMBLW1_RS18005	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GMBLW1_RS18010	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
GMBLW1_RS18025	COG1088	dTDP-glucose 4,6-dehydratase activity
GMBLW1_RS18040	COG3179	chitinase
GMBLW1_RS18045	COG2815	serine threonine protein kinase
GMBLW1_RS18045	COG0515	serine threonine protein kinase
GMBLW1_RS18090	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GMBLW1_RS18095	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GMBLW1_RS18100	COG0445	tRNA wobble uridine modification
GMBLW1_RS18120	COG1040	competence protein
GMBLW1_RS18135	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GMBLW1_RS18145	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
GMBLW1_RS18270	COG2205	protein histidine kinase activity
GMBLW1_RS18275	COG5002	protein histidine kinase activity
GMBLW1_RS18300	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
GMBLW1_RS18315	COG2154	pterin-4-alpha-carbinolamine dehydratase
GMBLW1_RS18340	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GMBLW1_RS18350	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GMBLW1_RS18360	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GMBLW1_RS18400	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GMBLW1_RS18420	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GMBLW1_RS18460	COG1136	(ABC) transporter
GMBLW1_RS18465	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GMBLW1_RS18485	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GMBLW1_RS18490	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GMBLW1_RS18495	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GMBLW1_RS18500	COG0416	fatty acid biosynthetic process
GMBLW1_RS18505	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GMBLW1_RS18515	COG0232	Belongs to the dGTPase family. Type 2 subfamily
GMBLW1_RS18520	COG4956	integral membrane protein (PIN domain superfamily)
GMBLW1_RS18590	COG3850	Histidine kinase
GMBLW1_RS18590	COG2205	protein histidine kinase activity
GMBLW1_RS18590	COG3437	response regulator, receiver
GMBLW1_RS18590	COG4999	Histidine kinase
GMBLW1_RS18630	COG1192	Involved in chromosome partitioning
GMBLW1_RS18645	COG2815	serine threonine protein kinase
GMBLW1_RS18645	COG0515	serine threonine protein kinase
GMBLW1_RS18665	COG0515	serine threonine protein kinase
GMBLW1_RS18675	COG0463	Glycosyl transferase, family 2
GMBLW1_RS18680	COG1473	amidohydrolase
GMBLW1_RS18690	COG1121	(ABC) transporter
GMBLW1_RS18720	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GMBLW1_RS18725	COG0750	zinc metalloprotease
GMBLW1_RS18750	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GMBLW1_RS18760	COG1216	Glycosyl transferase, family 2
GMBLW1_RS18775	COG2815	serine threonine protein kinase
GMBLW1_RS18775	COG0515	serine threonine protein kinase
GMBLW1_RS18810	COG1233	COG1233 Phytoene dehydrogenase and related
GMBLW1_RS18815	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GMBLW1_RS18830	COG3119	arylsulfatase activity
GMBLW1_RS18845	COG0588	phosphoglycerate mutase activity
GMBLW1_RS18860	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GMBLW1_RS18865	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GMBLW1_RS18880	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GMBLW1_RS18895	COG1122	ATPase activity
GMBLW1_RS18905	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
GMBLW1_RS18910	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
GMBLW1_RS18920	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
GMBLW1_RS18925	COG4208	sulfate ABC transporter
GMBLW1_RS18970	COG2815	serine threonine protein kinase
GMBLW1_RS18970	COG0515	serine threonine protein kinase
GMBLW1_RS18975	COG1331	Highly conserved protein containing a thioredoxin domain
GMBLW1_RS19040	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GMBLW1_RS19050	COG1032	radical SAM domain protein
GMBLW1_RS19065	COG0217	transcriptional regulatory protein
GMBLW1_RS19125	COG0612	Peptidase, M16
GMBLW1_RS19135	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GMBLW1_RS19140	COG1940	carbohydrate kinase activity
GMBLW1_RS19155	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GMBLW1_RS19175	COG0515	serine threonine protein kinase
GMBLW1_RS19180	COG2738	Putative neutral zinc metallopeptidase
GMBLW1_RS19190	COG0515	serine threonine protein kinase
GMBLW1_RS19210	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GMBLW1_RS19215	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GMBLW1_RS19230	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GMBLW1_RS19250	COG0475	glutathione-regulated potassium exporter activity
GMBLW1_RS19270	COG0438	transferase activity, transferring glycosyl groups
GMBLW1_RS19285	COG0006	proline dipeptidase activity
GMBLW1_RS19295	COG2226	methyltransferase
GMBLW1_RS19300	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GMBLW1_RS19310	COG1082	Xylose isomerase domain protein TIM barrel
GMBLW1_RS19320	COG0793	Belongs to the peptidase S41A family
GMBLW1_RS19355	COG2226	methyltransferase
GMBLW1_RS19365	COG2096	Adenosyltransferase
GMBLW1_RS19370	COG0724	RNA recognition motif
GMBLW1_RS19375	COG1595	DNA-templated transcription, initiation
GMBLW1_RS19385	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GMBLW1_RS19385	COG4797	methyltransferase
GMBLW1_RS19395	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GMBLW1_RS19400	COG0154	amidase activity
GMBLW1_RS19405	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GMBLW1_RS19410	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GMBLW1_RS19415	COG0709	Synthesizes selenophosphate from selenide and ATP
GMBLW1_RS19425	COG1819	glycosyl
GMBLW1_RS19475	COG2409	Drug exporters of the RND superfamily
GMBLW1_RS19485	COG0793	Belongs to the peptidase S41A family
GMBLW1_RS19495	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GMBLW1_RS19500	COG3541	Predicted nucleotidyltransferase
GMBLW1_RS19510	COG1064	alcohol dehydrogenase
GMBLW1_RS19515	COG2207	Transcriptional regulator
GMBLW1_RS19520	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
GMBLW1_RS19530	COG1028	Short-chain dehydrogenase reductase Sdr
GMBLW1_RS19565	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GMBLW1_RS19580	COG1595	DNA-templated transcription, initiation
GMBLW1_RS19605	COG1595	DNA-templated transcription, initiation
GMBLW1_RS19610	COG0386	Belongs to the glutathione peroxidase family
GMBLW1_RS19650	COG1902	pentaerythritol trinitrate reductase activity
GMBLW1_RS19660	COG0116	Belongs to the methyltransferase superfamily
GMBLW1_RS19660	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GMBLW1_RS19670	COG0527	aspartate kinase activity
GMBLW1_RS19675	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GMBLW1_RS19695	COG1012	belongs to the aldehyde dehydrogenase family
GMBLW1_RS19705	COG2226	methyltransferase
GMBLW1_RS19710	COG0673	inositol 2-dehydrogenase activity
GMBLW1_RS19715	COG0714	Associated with various cellular activities
GMBLW1_RS19745	COG1333	cytochrome c biogenesis protein
GMBLW1_RS19745	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GMBLW1_RS19780	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GMBLW1_RS19855	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GMBLW1_RS19875	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GMBLW1_RS19885	COG0531	amino acid
GMBLW1_RS19890	COG0009	L-threonylcarbamoyladenylate synthase
GMBLW1_RS19925	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GMBLW1_RS19930	COG0673	inositol 2-dehydrogenase activity
GMBLW1_RS19935	COG0602	queuosine metabolic process
GMBLW1_RS19945	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
GMBLW1_RS19960	COG0515	serine threonine protein kinase
GMBLW1_RS19970	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GMBLW1_RS19975	COG1192	Involved in chromosome partitioning
GMBLW1_RS20015	COG1131	(ABC) transporter
GMBLW1_RS20015	COG1716	ATPase activity
GMBLW1_RS20015	COG0842	Transport permease protein
GMBLW1_RS20040	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
GMBLW1_RS20055	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GMBLW1_RS20070	COG2815	serine threonine protein kinase
GMBLW1_RS20070	COG0515	serine threonine protein kinase
GMBLW1_RS20075	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GMBLW1_RS20080	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GMBLW1_RS20120	COG0515	serine threonine protein kinase
GMBLW1_RS20120	COG2815	serine threonine protein kinase
GMBLW1_RS20135	COG1131	(ABC) transporter
GMBLW1_RS20145	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GMBLW1_RS20150	COG2308	Evidence 4 Homologs of previously reported genes of
GMBLW1_RS20155	COG0259	pyridoxamine-phosphate oxidase activity
GMBLW1_RS20160	COG4969	Belongs to the N-Me-Phe pilin family
GMBLW1_RS20170	COG0823	Involved in the tonB-independent uptake of proteins
GMBLW1_RS20185	COG0517	IMP dehydrogenase activity
GMBLW1_RS20290	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GMBLW1_RS20325	COG0142	geranyltranstransferase activity
GMBLW1_RS20345	COG0673	inositol 2-dehydrogenase activity
GMBLW1_RS20360	COG0508	dehydrogenase complex catalyzes the overall conversion of
GMBLW1_RS20370	COG1519	Transferase
GMBLW1_RS20375	COG0653	protein targeting
GMBLW1_RS20390	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GMBLW1_RS20405	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GMBLW1_RS20425	COG0047	phosphoribosylformylglycinamidine synthase activity
GMBLW1_RS20430	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GMBLW1_RS20435	COG0180	Tryptophanyl-tRNA synthetase
GMBLW1_RS20445	COG0653	protein targeting
GMBLW1_RS20450	COG2204	response regulator
GMBLW1_RS20460	COG0515	serine threonine protein kinase
GMBLW1_RS20460	COG2815	serine threonine protein kinase
GMBLW1_RS20465	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GMBLW1_RS20470	COG0515	serine threonine protein kinase
GMBLW1_RS20470	COG2815	serine threonine protein kinase
GMBLW1_RS20490	COG0285	dihydrofolate synthase activity
GMBLW1_RS20495	COG3842	ATPase activity
GMBLW1_RS20505	COG0515	serine threonine protein kinase
GMBLW1_RS20505	COG2815	serine threonine protein kinase
GMBLW1_RS20525	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GMBLW1_RS20615	COG0515	serine threonine protein kinase
GMBLW1_RS20615	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GMBLW1_RS20625	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GMBLW1_RS20840	COG0612	Peptidase, M16
GMBLW1_RS20845	COG0612	Peptidase, M16
GMBLW1_RS20890	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GMBLW1_RS20905	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GMBLW1_RS20915	COG1063	alcohol dehydrogenase
GMBLW1_RS20955	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GMBLW1_RS20965	COG0045	succinate-CoA ligase (ADP-forming) activity
GMBLW1_RS20975	COG1959	2 iron, 2 sulfur cluster binding
GMBLW1_RS21070	COG0196	riboflavin kinase activity
GMBLW1_RS21095	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GMBLW1_RS21105	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GMBLW1_RS21110	COG3119	arylsulfatase activity
GMBLW1_RS21125	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GMBLW1_RS21130	COG0300	oxidoreductase activity
GMBLW1_RS21185	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GMBLW1_RS21200	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GMBLW1_RS21210	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GMBLW1_RS21210	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GMBLW1_RS21210	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GMBLW1_RS21215	COG1702	phosphate starvation-inducible protein PhoH
GMBLW1_RS21220	COG1480	7TM receptor with intracellular HD hydrolase
GMBLW1_RS21225	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
GMBLW1_RS21230	COG0322	excinuclease ABC activity
GMBLW1_RS21250	COG3046	protein related to deoxyribodipyrimidine photolyase
GMBLW1_RS21260	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GMBLW1_RS21280	COG0598	Magnesium transport protein CorA
GMBLW1_RS21300	COG1051	belongs to the nudix hydrolase family
GMBLW1_RS21380	COG2165	general secretion pathway protein
GMBLW1_RS21390	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
GMBLW1_RS21395	COG2271	Major facilitator Superfamily
GMBLW1_RS21400	COG4884	unkown
GMBLW1_RS21400	COG3831	ATPase activity
GMBLW1_RS21420	COG0640	Transcriptional regulator
GMBLW1_RS21425	COG2255	four-way junction helicase activity
GMBLW1_RS21430	COG0632	four-way junction helicase activity
GMBLW1_RS21435	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GMBLW1_RS21440	COG0215	cysteine-tRNA ligase activity
GMBLW1_RS21445	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GMBLW1_RS21450	COG0305	Participates in initiation and elongation during chromosome replication
GMBLW1_RS21455	COG0359	binds to the 23S rRNA
GMBLW1_RS21465	COG0360	Binds together with S18 to 16S ribosomal RNA
GMBLW1_RS21470	COG0193	aminoacyl-tRNA hydrolase activity
GMBLW1_RS21475	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GMBLW1_RS21520	COG1082	Xylose isomerase domain protein TIM barrel
GMBLW1_RS21535	COG0067	glutamate synthase
GMBLW1_RS21535	COG0070	glutamate synthase
GMBLW1_RS21535	COG0069	glutamate synthase activity
GMBLW1_RS21570	COG1131	(ABC) transporter
GMBLW1_RS21590	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GMBLW1_RS21610	COG0626	cystathionine gamma-synthase activity
GMBLW1_RS21650	COG0439	Biotin carboxylase
GMBLW1_RS21655	COG0511	ligase activity, forming carbon-carbon bonds
GMBLW1_RS21665	COG0515	serine threonine protein kinase
GMBLW1_RS21680	COG0284	orotidine-5'-phosphate decarboxylase activity
GMBLW1_RS21685	COG1404	Belongs to the peptidase S8 family
GMBLW1_RS21705	COG2189	Belongs to the N(4) N(6)-methyltransferase family
GMBLW1_RS21795	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GMBLW1_RS21800	COG0154	amidase activity
GMBLW1_RS21805	COG1104	cysteine desulfurase activity
GMBLW1_RS21820	COG5002	protein histidine kinase activity
GMBLW1_RS21830	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GMBLW1_RS21835	COG0792	nuclease activity
GMBLW1_RS21840	COG0335	large ribosomal subunit rRNA binding
GMBLW1_RS21845	COG0336	Belongs to the RNA methyltransferase TrmD family
GMBLW1_RS21850	COG0228	four-way junction DNA binding
GMBLW1_RS21855	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GMBLW1_RS21910	COG0275	rRNA processing
GMBLW1_RS21915	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GMBLW1_RS21925	COG1793	dna ligase
GMBLW1_RS21930	COG1201	RNA secondary structure unwinding
GMBLW1_RS21945	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GMBLW1_RS21965	COG1119	ATPase activity
GMBLW1_RS21970	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GMBLW1_RS21970	COG4651	solute:proton antiporter activity
GMBLW1_RS22020	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
GMBLW1_RS22035	COG2855	membrane
GMBLW1_RS22075	COG3293	Transposase
GMBLW1_RS22095	COG1648	precorrin-2 dehydrogenase activity
GMBLW1_RS22095	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GMBLW1_RS22115	COG0205	6-phosphofructokinase activity
GMBLW1_RS22120	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GMBLW1_RS22125	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GMBLW1_RS22160	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GMBLW1_RS22165	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GMBLW1_RS22190	COG0242	peptide deformylase activity
GMBLW1_RS22195	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GMBLW1_RS22210	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GMBLW1_RS22220	COG0714	Associated with various cellular activities
GMBLW1_RS22230	COG0753	catalase activity
GMBLW1_RS22245	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GMBLW1_RS22275	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
GMBLW1_RS22285	COG4245	von Willebrand factor, type A
GMBLW1_RS22290	COG0138	bifunctional purine biosynthesis protein purh
GMBLW1_RS22300	COG0438	transferase activity, transferring glycosyl groups
GMBLW1_RS22305	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GMBLW1_RS22350	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GMBLW1_RS22355	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GMBLW1_RS22360	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GMBLW1_RS22370	COG0765	amino acid transport
GMBLW1_RS22375	COG1126	abc transporter atp-binding protein
GMBLW1_RS22380	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
GMBLW1_RS22385	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
GMBLW1_RS22390	COG1131	(ABC) transporter
GMBLW1_RS22410	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
GMBLW1_RS22555	COG2304	oxidoreductase activity
GMBLW1_RS22600	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GMBLW1_RS22665	COG1408	metallophosphoesterase
GMBLW1_RS22700	COG3104	oligopeptide transport
GMBLW1_RS22705	COG1706	bacterial-type flagellum-dependent cell motility
GMBLW1_RS22710	COG1196	nuclear chromosome segregation
GMBLW1_RS22735	COG1196	nuclear chromosome segregation
GMBLW1_RS22760	COG1196	nuclear chromosome segregation
GMBLW1_RS22790	COG0515	serine threonine protein kinase
GMBLW1_RS22790	COG2815	serine threonine protein kinase
GMBLW1_RS22980	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GMBLW1_RS23005	COG3361	conserved protein (COG2071)
GMBLW1_RS23010	COG0842	Transport permease protein
GMBLW1_RS23010	COG1716	ATPase activity
GMBLW1_RS23010	COG1131	(ABC) transporter
GMBLW1_RS23080	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GMBLW1_RS23120	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GMBLW1_RS23150	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GMBLW1_RS23190	COG0347	Belongs to the P(II) protein family
GMBLW1_RS23250	COG0698	ribose 5-phosphate isomerase
GMBLW1_RS23255	COG0443	Heat shock 70 kDa protein
GMBLW1_RS23300	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GMBLW1_RS23305	COG0358	DNA primase activity
GMBLW1_RS23350	COG0673	inositol 2-dehydrogenase activity
GMBLW1_RS23410	COG0629	single-stranded DNA binding
GMBLW1_RS23470	COG1192	Involved in chromosome partitioning
GMBLW1_RS23535	COG1201	RNA secondary structure unwinding
GMBLW1_RS23555	COG0514	ATP-dependent DNA helicase (RecQ)
GMBLW1_RS23560	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GMBLW1_RS23645	COG0408	coproporphyrinogen oxidase activity
GMBLW1_RS23670	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GMBLW1_RS23675	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GMBLW1_RS23680	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GMBLW1_RS23700	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GMBLW1_RS23945	COG1073	alpha beta
GMBLW1_RS23985	COG0415	Belongs to the DNA photolyase family
GMBLW1_RS24005	COG2226	methyltransferase
GMBLW1_RS24020	COG1064	alcohol dehydrogenase
GMBLW1_RS24025	COG4145	pantothenate transmembrane transporter activity
GMBLW1_RS24070	COG1028	Short-chain dehydrogenase reductase Sdr
GMBLW1_RS24075	COG0367	asparagine synthase
GMBLW1_RS24085	COG1136	(ABC) transporter
GMBLW1_RS24110	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GMBLW1_RS24130	COG0346	lactoylglutathione lyase activity
GMBLW1_RS24140	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GMBLW1_RS24145	COG0515	serine threonine protein kinase
GMBLW1_RS24145	COG2815	serine threonine protein kinase
GMBLW1_RS24150	COG2264	protein methyltransferase activity
GMBLW1_RS24190	COG3119	arylsulfatase activity
GMBLW1_RS24205	COG1073	alpha beta
GMBLW1_RS24215	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GMBLW1_RS24225	COG0517	IMP dehydrogenase activity
GMBLW1_RS24225	COG0516	GMP reductase activity
GMBLW1_RS24240	COG2815	serine threonine protein kinase
GMBLW1_RS24240	COG0515	serine threonine protein kinase
GMBLW1_RS24260	COG1505	serine-type exopeptidase activity
GMBLW1_RS24295	COG1595	DNA-templated transcription, initiation
GMBLW1_RS24330	COG0515	serine threonine protein kinase
GMBLW1_RS24330	COG2815	serine threonine protein kinase
GMBLW1_RS24335	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GMBLW1_RS24345	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
GMBLW1_RS24365	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GMBLW1_RS24380	COG3119	arylsulfatase activity
GMBLW1_RS24385	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GMBLW1_RS24400	COG0556	nucleotide-excision repair
GMBLW1_RS24410	COG1132	(ABC) transporter
GMBLW1_RS24415	COG2815	serine threonine protein kinase
GMBLW1_RS24415	COG0515	serine threonine protein kinase
GMBLW1_RS24430	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GMBLW1_RS24445	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GMBLW1_RS24450	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GMBLW1_RS24465	COG2195	Cleaves the N-terminal amino acid of tripeptides
GMBLW1_RS24480	COG2815	serine threonine protein kinase
GMBLW1_RS24480	COG0515	serine threonine protein kinase
GMBLW1_RS24485	COG2226	methyltransferase
GMBLW1_RS24500	COG2815	serine threonine protein kinase
GMBLW1_RS24500	COG0515	serine threonine protein kinase
GMBLW1_RS24530	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GMBLW1_RS24540	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GMBLW1_RS24575	COG2271	Major facilitator Superfamily
GMBLW1_RS24585	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GMBLW1_RS24605	COG0440	acetolactate synthase activity
GMBLW1_RS24620	COG0515	serine threonine protein kinase
GMBLW1_RS24620	COG2815	serine threonine protein kinase
GMBLW1_RS24625	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GMBLW1_RS24655	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GMBLW1_RS24665	COG3119	arylsulfatase activity
GMBLW1_RS24710	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GMBLW1_RS24740	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GMBLW1_RS24785	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GMBLW1_RS24930	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GMBLW1_RS24950	COG2815	serine threonine protein kinase
GMBLW1_RS24950	COG0515	serine threonine protein kinase
GMBLW1_RS24960	COG0482	sulfurtransferase activity
GMBLW1_RS24975	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GMBLW1_RS24980	COG4591	ABC-type transport system involved in lipoprotein release permease component
GMBLW1_RS24985	COG1136	(ABC) transporter
GMBLW1_RS25005	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GMBLW1_RS25010	COG2815	serine threonine protein kinase
GMBLW1_RS25010	COG0515	serine threonine protein kinase
GMBLW1_RS25020	COG5564	TIM-barrel signal transduction protein
GMBLW1_RS25040	COG1858	cytochrome C peroxidase
GMBLW1_RS25045	COG3132	Protein of unknown function, DUF480
GMBLW1_RS25075	COG0318	PFAM AMP-dependent synthetase and ligase
GMBLW1_RS25080	COG0583	DNA-binding transcription factor activity
GMBLW1_RS25090	COG0673	inositol 2-dehydrogenase activity
GMBLW1_RS25105	COG0861	Integral membrane protein TerC family
GMBLW1_RS25135	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GMBLW1_RS25140	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GMBLW1_RS25175	COG0842	Transport permease protein
GMBLW1_RS25175	COG1129	ABC transporter
GMBLW1_RS25200	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GMBLW1_RS25210	COG0673	inositol 2-dehydrogenase activity
GMBLW1_RS25215	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
GMBLW1_RS25235	COG1082	Xylose isomerase domain protein TIM barrel
GMBLW1_RS25260	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GMBLW1_RS25260	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GMBLW1_RS25285	COG0473	3-isopropylmalate dehydrogenase activity
GMBLW1_RS25295	COG4106	trans-aconitate 2-methyltransferase activity
GMBLW1_RS25325	COG4964	Belongs to the GSP D family
GMBLW1_RS25385	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GMBLW1_RS25395	COG4284	Utp--glucose-1-phosphate uridylyltransferase
GMBLW1_RS25400	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GMBLW1_RS25400	COG0321	lipoyl(octanoyl) transferase activity
GMBLW1_RS25415	COG2195	Cleaves the N-terminal amino acid of tripeptides
GMBLW1_RS25430	COG2258	MOSC domain
GMBLW1_RS25455	COG0754	glutathionylspermidine amidase activity
GMBLW1_RS25495	COG0528	UMP kinase activity
GMBLW1_RS25500	COG0233	cytoplasmic translational termination
GMBLW1_RS25505	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GMBLW1_RS25510	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GMBLW1_RS25515	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GMBLW1_RS25530	COG0784	Response regulator, receiver
GMBLW1_RS25530	COG2198	Histidine kinase
GMBLW1_RS25530	COG5002	protein histidine kinase activity
GMBLW1_RS25535	COG0546	phosphoglycolate phosphatase activity
GMBLW1_RS25550	COG0406	alpha-ribazole phosphatase activity
GMBLW1_RS25560	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GMBLW1_RS25590	COG0714	Associated with various cellular activities
GMBLW1_RS25640	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GMBLW1_RS25655	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GMBLW1_RS25660	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GMBLW1_RS25675	COG3795	YCII-related domain
GMBLW1_RS25680	COG2226	methyltransferase
GMBLW1_RS25685	COG1136	(ABC) transporter
GMBLW1_RS25705	COG0673	inositol 2-dehydrogenase activity
GMBLW1_RS25710	COG0673	inositol 2-dehydrogenase activity
GMBLW1_RS25800	COG0123	including yeast histone deacetylase and acetoin utilization protein
GMBLW1_RS25835	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate