locus-tag	class	description
EJN92_RS00040	COG0501	Belongs to the peptidase M48B family
EJN92_RS00075	COG5002	protein histidine kinase activity
EJN92_RS00075	COG0784	Response regulator, receiver
EJN92_RS00105	COG1028	Short-chain dehydrogenase reductase Sdr
EJN92_RS00115	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EJN92_RS00120	COG0583	DNA-binding transcription factor activity
EJN92_RS00125	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EJN92_RS00140	COG5001	Diguanylate cyclase
EJN92_RS00140	COG3300	MHYT domain
EJN92_RS00145	COG0840	transmembrane signaling receptor activity
EJN92_RS00150	COG0542	response to heat
EJN92_RS00160	COG0314	molybdopterin synthase activity
EJN92_RS00170	COG0303	'Molybdopterin
EJN92_RS00190	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EJN92_RS00200	COG1028	Short-chain dehydrogenase reductase Sdr
EJN92_RS00205	COG3243	poly(R)-hydroxyalkanoic acid synthase
EJN92_RS00215	COG1496	oxidoreductase activity
EJN92_RS00220	COG0564	pseudouridine synthase activity
EJN92_RS00230	COG3022	response to hydroperoxide
EJN92_RS00240	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
EJN92_RS00245	COG0643	Histidine kinase
EJN92_RS00245	COG0784	Response regulator, receiver
EJN92_RS00245	COG2198	Histidine kinase
EJN92_RS00250	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EJN92_RS00255	COG2917	probably involved in intracellular septation
EJN92_RS00260	COG0271	Belongs to the BolA IbaG family
EJN92_RS00265	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EJN92_RS00290	COG0484	heat shock protein binding
EJN92_RS00295	COG1047	Peptidyl-prolyl cis-trans
EJN92_RS00300	COG3590	peptidase
EJN92_RS00305	COG1199	ATP-dependent helicase activity
EJN92_RS00315	COG0631	protein serine/threonine phosphatase activity
EJN92_RS00320	COG0625	glutathione transferase activity
EJN92_RS00335	COG0483	inositol monophosphate 1-phosphatase activity
EJN92_RS00340	COG0513	Belongs to the DEAD box helicase family
EJN92_RS00350	COG2972	Histidine kinase
EJN92_RS00355	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EJN92_RS00365	COG2850	peptidyl-arginine hydroxylation
EJN92_RS00380	COG0745	RESPONSE REGULATOR receiver
EJN92_RS00385	COG2201	protein-glutamate methylesterase activity
EJN92_RS00390	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
EJN92_RS00400	COG0840	transmembrane signaling receptor activity
EJN92_RS00405	COG0835	chemotaxis
EJN92_RS00415	COG0745	RESPONSE REGULATOR receiver
EJN92_RS00425	COG1360	Flagellar Motor Protein
EJN92_RS00455	COG0037	tRNA processing
EJN92_RS00460	COG0825	malonyl-CoA metabolic process
EJN92_RS00470	COG3063	Type IV pilus biogenesis stability protein PilW
EJN92_RS00485	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EJN92_RS00490	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EJN92_RS00495	COG1045	serine acetyltransferase
EJN92_RS00500	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EJN92_RS00505	COG0557	exoribonuclease II activity
EJN92_RS00520	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
EJN92_RS00525	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EJN92_RS00530	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EJN92_RS00535	COG0330	HflC and HflK could
EJN92_RS00540	COG0330	HflC and HflK could
EJN92_RS00545	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EJN92_RS00550	COG1923	regulation of RNA biosynthetic process
EJN92_RS00555	COG1160	GTP binding
EJN92_RS00570	COG0124	histidyl-tRNA synthetase
EJN92_RS00575	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EJN92_RS00580	COG1426	Protein conserved in bacteria
EJN92_RS00590	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EJN92_RS00595	COG0105	UTP biosynthetic process
EJN92_RS00620	COG0583	DNA-binding transcription factor activity
EJN92_RS00630	COG0840	transmembrane signaling receptor activity
EJN92_RS00640	COG1132	(ABC) transporter
EJN92_RS00645	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EJN92_RS00645	COG0189	ligase activity
EJN92_RS00650	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EJN92_RS00650	COG0189	ligase activity
EJN92_RS00730	COG2373	Large extracellular alpha-helical protein
EJN92_RS00735	COG2814	Major facilitator Superfamily
EJN92_RS00740	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EJN92_RS00815	COG3126	Type III secretion system lipoprotein chaperone (YscW)
EJN92_RS00835	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
EJN92_RS00865	COG3158	transport of potassium into the cell
EJN92_RS00880	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EJN92_RS00900	COG0745	RESPONSE REGULATOR receiver
EJN92_RS00905	COG2205	protein histidine kinase activity
EJN92_RS00910	COG1272	protein, Hemolysin III
EJN92_RS00920	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
EJN92_RS00955	COG1595	DNA-templated transcription, initiation
EJN92_RS00960	COG1309	transcriptional regulator
EJN92_RS00990	COG2378	regulation of single-species biofilm formation
EJN92_RS00995	COG0789	Transcriptional regulator
EJN92_RS01010	COG0454	-acetyltransferase
EJN92_RS01035	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EJN92_RS01040	COG0508	dehydrogenase complex catalyzes the overall conversion of
EJN92_RS01050	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EJN92_RS01075	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EJN92_RS01105	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EJN92_RS01110	COG0322	excinuclease ABC activity
EJN92_RS01115	COG0736	holo-[acyl-carrier-protein] synthase activity
EJN92_RS01125	COG1381	Involved in DNA repair and RecF pathway recombination
EJN92_RS01130	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EJN92_RS01135	COG0571	ribonuclease III activity
EJN92_RS01145	COG0681	Belongs to the peptidase S26 family
EJN92_RS01150	COG0481	GTPase activity
EJN92_RS01155	COG0101	tRNA pseudouridine synthase activity
EJN92_RS01165	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EJN92_RS01170	COG0473	3-isopropylmalate dehydrogenase activity
EJN92_RS01175	COG0066	3-isopropylmalate dehydratase activity
EJN92_RS01185	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EJN92_RS01190	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EJN92_RS01210	COG3547	Transposase (IS116 IS110 IS902 family)
EJN92_RS01215	COG0306	phosphate transporter
EJN92_RS01230	COG0359	binds to the 23S rRNA
EJN92_RS01235	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EJN92_RS01245	COG0360	Binds together with S18 to 16S ribosomal RNA
EJN92_RS01250	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EJN92_RS01255	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EJN92_RS01260	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EJN92_RS01265	COG0740	serine-type endopeptidase activity
EJN92_RS01270	COG0544	peptidyl-prolyl cis-trans isomerase activity
EJN92_RS01285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EJN92_RS01290	COG1562	ergosterol biosynthetic process
EJN92_RS01310	COG1562	ergosterol biosynthetic process
EJN92_RS01365	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
EJN92_RS01415	COG2095	MarC family integral membrane protein
EJN92_RS01420	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EJN92_RS01425	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EJN92_RS01430	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EJN92_RS01435	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EJN92_RS01500	COG4372	Transposase
EJN92_RS01515	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EJN92_RS01520	COG0251	oxidation-reduction process
EJN92_RS01530	COG1028	Short-chain dehydrogenase reductase Sdr
EJN92_RS01555	COG4942	peptidase
EJN92_RS01590	COG4566	intracellular signal transduction
EJN92_RS01600	COG1028	Short-chain dehydrogenase reductase Sdr
EJN92_RS01610	COG0494	nUDIX hydrolase
EJN92_RS01620	COG1007	ATP synthesis coupled electron transport
EJN92_RS01635	COG0713	ATP synthesis coupled electron transport
EJN92_RS01645	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EJN92_RS01650	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EJN92_RS01655	COG1034	ATP synthesis coupled electron transport
EJN92_RS01670	COG0649	NAD binding
EJN92_RS01675	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EJN92_RS01680	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EJN92_RS01685	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EJN92_RS01700	COG0149	triose-phosphate isomerase activity
EJN92_RS01710	COG1185	polyribonucleotide nucleotidyltransferase activity
EJN92_RS01715	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EJN92_RS01725	COG1183	phosphatidylcholine synthase activity
EJN92_RS01730	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EJN92_RS01740	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EJN92_RS01745	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EJN92_RS01750	COG3850	Histidine kinase
EJN92_RS01750	COG2205	protein histidine kinase activity
EJN92_RS01750	COG3437	response regulator, receiver
EJN92_RS01750	COG4999	Histidine kinase
EJN92_RS01770	COG1448	Aminotransferase
EJN92_RS01795	COG0583	DNA-binding transcription factor activity
EJN92_RS01875	COG4221	oxidoreductase activity
EJN92_RS01890	COG2267	carboxylic ester hydrolase activity
EJN92_RS01905	COG0697	spore germination
EJN92_RS01910	COG1280	lysine exporter protein (LysE YggA)
EJN92_RS01915	COG0300	oxidoreductase activity
EJN92_RS01925	COG0583	DNA-binding transcription factor activity
EJN92_RS01930	COG0625	glutathione transferase activity
EJN92_RS01940	COG2814	Major facilitator Superfamily
EJN92_RS01970	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EJN92_RS01980	COG1538	Outer membrane efflux protein
EJN92_RS01990	COG0625	glutathione transferase activity
EJN92_RS02025	COG0840	transmembrane signaling receptor activity
EJN92_RS02040	COG0840	transmembrane signaling receptor activity
EJN92_RS02095	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EJN92_RS02100	COG2814	Major facilitator Superfamily
EJN92_RS02110	COG1858	cytochrome C peroxidase
EJN92_RS02125	COG2072	flavoprotein involved in K transport
EJN92_RS02130	COG3275	phosphorelay sensor kinase activity
EJN92_RS02205	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EJN92_RS02225	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EJN92_RS02235	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EJN92_RS02245	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
EJN92_RS02280	COG1045	serine acetyltransferase
EJN92_RS02295	COG2244	polysaccharide biosynthetic process
EJN92_RS02365	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EJN92_RS02380	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EJN92_RS02385	COG0826	peptidase U32
EJN92_RS02420	COG0326	Molecular chaperone. Has ATPase activity
EJN92_RS02445	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EJN92_RS02450	COG1702	phosphate starvation-inducible protein PhoH
EJN92_RS02455	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EJN92_RS02465	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EJN92_RS02475	COG0009	L-threonylcarbamoyladenylate synthase
EJN92_RS02480	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EJN92_RS02485	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EJN92_RS02490	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EJN92_RS02500	COG0469	pyruvate kinase activity
EJN92_RS02505	COG0126	phosphoglycerate kinase activity
EJN92_RS02530	COG0429	hydrolase of the alpha beta-hydrolase fold
EJN92_RS02540	COG4783	chaperone-mediated protein folding
EJN92_RS02545	COG0315	cyclic pyranopterin monophosphate synthase activity
EJN92_RS02560	COG3307	-O-antigen
EJN92_RS02580	COG0631	protein serine/threonine phosphatase activity
EJN92_RS02585	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EJN92_RS02590	COG0045	succinate-CoA ligase (ADP-forming) activity
EJN92_RS02600	COG2137	regulation of response to DNA damage stimulus
EJN92_RS02605	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EJN92_RS02615	COG0709	Synthesizes selenophosphate from selenide and ATP
EJN92_RS02620	COG0513	Belongs to the DEAD box helicase family
EJN92_RS02640	COG3842	ATPase activity
EJN92_RS02650	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EJN92_RS02655	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EJN92_RS02660	COG0584	glycerophosphoryl diester phosphodiesterase
EJN92_RS02665	COG4974	Belongs to the 'phage' integrase family
EJN92_RS02725	COG3590	peptidase
EJN92_RS02730	COG0840	transmembrane signaling receptor activity
EJN92_RS02740	COG2205	protein histidine kinase activity
EJN92_RS02740	COG2198	Histidine kinase
EJN92_RS02740	COG0784	Response regulator, receiver
EJN92_RS02740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EJN92_RS02745	COG0402	S-adenosylhomocysteine deaminase activity
EJN92_RS02755	COG0700	Nucleoside recognition
EJN92_RS02810	COG3220	belongs to the UPF0276 family
EJN92_RS02835	COG1763	Mo-molybdopterin cofactor biosynthetic process
EJN92_RS02840	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
EJN92_RS02845	COG0166	Belongs to the GPI family
EJN92_RS02860	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EJN92_RS02865	COG0363	glucosamine-6-phosphate deaminase activity
EJN92_RS02900	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
EJN92_RS02905	COG1187	pseudouridine synthase activity
EJN92_RS02915	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EJN92_RS02925	COG0697	spore germination
EJN92_RS02965	COG0542	response to heat
EJN92_RS02980	COG1090	epimerase
EJN92_RS03005	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EJN92_RS03010	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EJN92_RS03015	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EJN92_RS03020	COG0195	Participates in both transcription termination and antitermination
EJN92_RS03020	COG2251	uridine kinase activity
EJN92_RS03025	COG0779	Required for maturation of 30S ribosomal subunits
EJN92_RS03030	COG1187	pseudouridine synthase activity
EJN92_RS03035	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EJN92_RS03045	COG1051	belongs to the nudix hydrolase family
EJN92_RS03050	COG0004	ammonium transporteR
EJN92_RS03055	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
EJN92_RS03060	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
EJN92_RS03065	COG0167	dihydroorotate dehydrogenase activity
EJN92_RS03070	COG0667	Aldo Keto reductase
EJN92_RS03075	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EJN92_RS03100	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EJN92_RS03115	COG0730	response to heat
EJN92_RS03120	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EJN92_RS03130	COG0175	sulfate reduction
EJN92_RS03150	COG5002	protein histidine kinase activity
EJN92_RS03160	COG1136	(ABC) transporter
EJN92_RS03160	COG0577	efflux transmembrane transporter activity
EJN92_RS03165	COG0577	efflux transmembrane transporter activity
EJN92_RS03170	COG1136	(ABC) transporter
EJN92_RS03185	COG0795	lipopolysaccharide-transporting ATPase activity
EJN92_RS03190	COG0795	lipopolysaccharide-transporting ATPase activity
EJN92_RS03195	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EJN92_RS03200	COG0708	Exodeoxyribonuclease III
EJN92_RS03220	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EJN92_RS03250	COG4251	negative regulation of phosphorylation
EJN92_RS03250	COG3706	GGDEF domain
EJN92_RS03250	COG5001	Diguanylate cyclase
EJN92_RS03250	COG2203	Gaf domain
EJN92_RS03255	COG4191	Histidine kinase
EJN92_RS03265	COG1288	antiporter activity
EJN92_RS03275	COG1737	Transcriptional regulator
EJN92_RS03280	COG4206	TonB-dependent receptor
EJN92_RS03315	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EJN92_RS03330	COG0668	transmembrane transport
EJN92_RS03335	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EJN92_RS03335	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EJN92_RS03340	COG0509	glycine decarboxylation via glycine cleavage system
EJN92_RS03345	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EJN92_RS03360	COG2195	Cleaves the N-terminal amino acid of tripeptides
EJN92_RS03375	COG0745	RESPONSE REGULATOR receiver
EJN92_RS03415	COG0837	glucose binding
EJN92_RS03440	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EJN92_RS03450	COG0366	Alpha amylase catalytic
EJN92_RS03460	COG1501	Belongs to the glycosyl hydrolase 31 family
EJN92_RS03465	COG0366	Alpha amylase catalytic
EJN92_RS03480	COG0802	atpase or kinase
EJN92_RS03485	COG0860	N-Acetylmuramoyl-L-alanine amidase
EJN92_RS03495	COG0586	Pfam SNARE associated Golgi protein
EJN92_RS03500	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EJN92_RS03505	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EJN92_RS03540	COG4166	transmembrane transport
EJN92_RS03550	COG0601	transmembrane transport
EJN92_RS03590	COG0667	Aldo Keto reductase
EJN92_RS03605	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EJN92_RS03615	COG0642	Histidine kinase
EJN92_RS03630	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EJN92_RS03655	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EJN92_RS03660	COG0129	dihydroxy-acid dehydratase activity
EJN92_RS03665	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
EJN92_RS03670	COG0308	aminopeptidase N
EJN92_RS03685	COG0697	spore germination
EJN92_RS03690	COG0217	transcriptional regulatory protein
EJN92_RS03695	COG0151	Belongs to the GarS family
EJN92_RS03700	COG0408	coproporphyrinogen oxidase activity
EJN92_RS03705	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EJN92_RS03710	COG0799	negative regulation of ribosome biogenesis
EJN92_RS03715	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EJN92_RS03720	COG0424	maF-like protein
EJN92_RS03725	COG1530	ribonuclease E activity
EJN92_RS03750	COG4372	Transposase
EJN92_RS03800	COG4372	Transposase
EJN92_RS03830	COG4372	Transposase
EJN92_RS03855	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EJN92_RS03900	COG4372	Transposase
EJN92_RS03915	COG0842	Transport permease protein
EJN92_RS03920	COG0842	Transport permease protein
EJN92_RS03920	COG1129	ABC transporter
EJN92_RS03925	COG0842	Transport permease protein
EJN92_RS03925	COG1129	ABC transporter
EJN92_RS03930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EJN92_RS03940	COG3243	poly(R)-hydroxyalkanoic acid synthase
EJN92_RS03955	COG1132	(ABC) transporter
EJN92_RS03970	COG1054	Belongs to the UPF0176 family
EJN92_RS03975	COG1741	Belongs to the pirin family
EJN92_RS03980	COG0513	Belongs to the DEAD box helicase family
EJN92_RS03990	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EJN92_RS04005	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EJN92_RS04010	COG2081	HI0933 family
EJN92_RS04025	COG4771	TonB-dependent receptor
EJN92_RS04035	COG3706	GGDEF domain
EJN92_RS04055	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EJN92_RS04065	COG1070	Carbohydrate kinase
EJN92_RS04070	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EJN92_RS04075	COG0277	FAD linked oxidase domain protein
EJN92_RS04085	COG0010	Belongs to the arginase family
EJN92_RS04090	COG0583	DNA-binding transcription factor activity
EJN92_RS04125	COG0697	spore germination
EJN92_RS04140	COG4206	TonB-dependent receptor
EJN92_RS04150	COG1136	(ABC) transporter
EJN92_RS04170	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EJN92_RS04175	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EJN92_RS04190	COG1309	transcriptional regulator
EJN92_RS04230	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EJN92_RS04235	COG0798	PFAM Bile acid sodium symporter
EJN92_RS04240	COG0431	NADPH-dependent FMN reductase
EJN92_RS04245	COG1028	Short-chain dehydrogenase reductase Sdr
EJN92_RS04250	COG1609	Transcriptional regulator
EJN92_RS04255	COG2723	6-phospho-beta-galactosidase activity
EJN92_RS04260	COG0475	glutathione-regulated potassium exporter activity
EJN92_RS04265	COG4771	TonB-dependent receptor
EJN92_RS04280	COG5002	protein histidine kinase activity
EJN92_RS04310	COG1968	undecaprenyl-diphosphatase activity
EJN92_RS04315	COG0514	ATP-dependent DNA helicase (RecQ)
EJN92_RS04325	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EJN92_RS04340	COG0456	acetyltransferase
EJN92_RS04350	COG0583	DNA-binding transcription factor activity
EJN92_RS04360	COG1278	Cold shock
EJN92_RS04375	COG0752	glycyl-tRNA synthetase alpha subunit
EJN92_RS04380	COG0751	glycine-tRNA ligase activity
EJN92_RS04385	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EJN92_RS04400	COG0346	lactoylglutathione lyase activity
EJN92_RS04445	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EJN92_RS04450	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EJN92_RS04510	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
EJN92_RS04530	COG3852	Histidine kinase
EJN92_RS04540	COG0174	glutamine synthetase
EJN92_RS04550	COG3383	formate dehydrogenase (NAD+) activity
EJN92_RS04600	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EJN92_RS04600	COG1116	anion transmembrane transporter activity
EJN92_RS04605	COG1116	anion transmembrane transporter activity
EJN92_RS04605	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EJN92_RS04610	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EJN92_RS04615	COG1116	anion transmembrane transporter activity
EJN92_RS04620	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
EJN92_RS04630	COG1846	Transcriptional regulator
EJN92_RS04635	COG1764	response to oxidative stress
EJN92_RS04655	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EJN92_RS04660	COG0459	protein refolding
EJN92_RS04690	COG0632	four-way junction helicase activity
EJN92_RS04695	COG2255	four-way junction helicase activity
EJN92_RS04700	COG1671	Belongs to the UPF0178 family
EJN92_RS04720	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
EJN92_RS04730	COG0210	DNA helicase
EJN92_RS04735	COG0352	thiamine-phosphate diphosphorylase activity
EJN92_RS04740	COG0351	phosphomethylpyrimidine kinase
EJN92_RS04745	COG2022	thiamine diphosphate biosynthetic process
EJN92_RS04755	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EJN92_RS04775	COG1012	belongs to the aldehyde dehydrogenase family
EJN92_RS04780	COG3284	Transcriptional regulator
EJN92_RS04805	COG2885	chlorophyll binding
EJN92_RS04840	COG3275	phosphorelay sensor kinase activity
EJN92_RS04845	COG1668	transmembrane transport
EJN92_RS04850	COG4555	ABC transporter
EJN92_RS04860	COG1194	a g-specific adenine glycosylase
EJN92_RS04865	COG4771	TonB-dependent receptor
EJN92_RS04875	COG2423	ornithine cyclodeaminase activity
EJN92_RS04880	COG0006	proline dipeptidase activity
EJN92_RS04890	COG3291	Pkd domain containing protein
EJN92_RS04900	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EJN92_RS04910	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
EJN92_RS04915	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EJN92_RS04925	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EJN92_RS04930	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EJN92_RS04935	COG0405	Gamma-glutamyltransferase
EJN92_RS04955	COG1522	sequence-specific DNA binding
EJN92_RS04960	COG0626	cystathionine gamma-synthase activity
EJN92_RS05000	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EJN92_RS05015	COG0402	S-adenosylhomocysteine deaminase activity
EJN92_RS05025	COG0762	integral membrane protein
EJN92_RS05040	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EJN92_RS05040	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EJN92_RS05060	COG0295	cytidine deaminase activity
EJN92_RS05065	COG0412	Dienelactone hydrolase
EJN92_RS05070	COG0824	Thioesterase
EJN92_RS05095	COG1950	PFAM Membrane protein of
EJN92_RS05100	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EJN92_RS05105	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EJN92_RS05120	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EJN92_RS05135	COG1137	ATPase activity
EJN92_RS05140	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EJN92_RS05145	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EJN92_RS05160	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EJN92_RS05205	COG1965	Belongs to the frataxin family
EJN92_RS05215	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
EJN92_RS05220	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EJN92_RS05230	COG1132	(ABC) transporter
EJN92_RS05235	COG1132	(ABC) transporter
EJN92_RS05240	COG1505	serine-type exopeptidase activity
EJN92_RS05245	COG0789	Transcriptional regulator
EJN92_RS05260	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EJN92_RS05270	COG1560	Kdo2-lipid A biosynthetic process
EJN92_RS05280	COG3186	Phenylalanine-4-hydroxylase
EJN92_RS05290	COG1522	sequence-specific DNA binding
EJN92_RS05320	COG3590	peptidase
EJN92_RS05330	COG1522	sequence-specific DNA binding
EJN92_RS05335	COG1309	transcriptional regulator
EJN92_RS05350	COG1953	Uracil, thiamine, allantoin
EJN92_RS05365	COG1943	Transposase
EJN92_RS05400	COG4191	Histidine kinase
EJN92_RS05400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EJN92_RS05420	COG0446	pyridine nucleotide-disulphide oxidoreductase
EJN92_RS05440	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EJN92_RS05450	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EJN92_RS05480	COG3409	Peptidoglycan-binding domain 1 protein
EJN92_RS05480	COG3267	Type II secretory pathway component ExeA
EJN92_RS05530	COG2165	general secretion pathway protein
EJN92_RS05535	COG2165	general secretion pathway protein
EJN92_RS05545	COG1459	type II secretion system
EJN92_RS05550	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EJN92_RS05555	COG0123	including yeast histone deacetylase and acetoin utilization protein
EJN92_RS05560	COG0714	Associated with various cellular activities
EJN92_RS05575	COG2951	lytic endotransglycosylase activity
EJN92_RS05590	COG2217	Heavy metal translocating P-type atpase
EJN92_RS05605	COG1538	Outer membrane efflux protein
EJN92_RS05615	COG0516	GMP reductase activity
EJN92_RS05650	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EJN92_RS05660	COG0259	pyridoxamine-phosphate oxidase activity
EJN92_RS05665	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EJN92_RS05675	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EJN92_RS05705	COG4969	Belongs to the N-Me-Phe pilin family
EJN92_RS05710	COG0247	lactate metabolic process
EJN92_RS05715	COG0277	FAD linked oxidase domain protein
EJN92_RS05720	COG0277	FAD linked oxidase domain protein
EJN92_RS05725	COG0316	Belongs to the HesB IscA family
EJN92_RS05740	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EJN92_RS05745	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EJN92_RS05750	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EJN92_RS05755	COG1765	OsmC-like protein
EJN92_RS05765	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EJN92_RS05775	COG1611	Belongs to the LOG family
EJN92_RS05780	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EJN92_RS05780	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EJN92_RS05785	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EJN92_RS05790	COG1333	cytochrome c biogenesis protein
EJN92_RS05800	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EJN92_RS05815	COG0598	Magnesium transport protein CorA
EJN92_RS05820	COG2925	Exonuclease
EJN92_RS05825	COG4232	protein-disulfide reductase activity
EJN92_RS05830	COG0203	ribosomal protein L17
EJN92_RS05835	COG0202	RNA polymerase activity
EJN92_RS05840	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EJN92_RS05845	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EJN92_RS05850	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EJN92_RS05855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EJN92_RS05860	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EJN92_RS05865	COG0201	protein transport
EJN92_RS05870	COG0200	Binds to the 23S rRNA
EJN92_RS05875	COG1841	ribosomal large subunit assembly
EJN92_RS05880	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EJN92_RS05885	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EJN92_RS05890	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EJN92_RS05895	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EJN92_RS05900	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EJN92_RS05905	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EJN92_RS05910	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EJN92_RS05915	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EJN92_RS05925	COG0255	Belongs to the universal ribosomal protein uL29 family
EJN92_RS05930	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EJN92_RS05935	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EJN92_RS05940	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EJN92_RS05945	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EJN92_RS05950	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EJN92_RS05955	COG0089	rRNA binding
EJN92_RS05960	COG0088	Forms part of the polypeptide exit tunnel
EJN92_RS05965	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EJN92_RS05970	COG0051	transcription antitermination factor activity, RNA binding
EJN92_RS05975	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EJN92_RS05980	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EJN92_RS05985	COG0049	tRNA binding
EJN92_RS05990	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EJN92_RS05995	COG2194	sulfuric ester hydrolase activity
EJN92_RS06000	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EJN92_RS06005	COG1127	ABC transporter
EJN92_RS06035	COG1686	Belongs to the peptidase S11 family
EJN92_RS06045	COG2921	Belongs to the UPF0250 family
EJN92_RS06050	COG0583	DNA-binding transcription factor activity
EJN92_RS06065	COG0321	lipoyl(octanoyl) transferase activity
EJN92_RS06070	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EJN92_RS06105	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EJN92_RS06130	COG0730	response to heat
EJN92_RS06130	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EJN92_RS06135	COG0640	Transcriptional regulator
EJN92_RS06150	COG0205	6-phosphofructokinase activity
EJN92_RS06170	COG1253	flavin adenine dinucleotide binding
EJN92_RS06190	COG1538	Outer membrane efflux protein
EJN92_RS06195	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EJN92_RS06205	COG2826	transposase and inactivated derivatives, IS30 family
EJN92_RS06230	COG2815	serine threonine protein kinase
EJN92_RS06230	COG0515	serine threonine protein kinase
EJN92_RS06245	COG0346	lactoylglutathione lyase activity
EJN92_RS06265	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
EJN92_RS06285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EJN92_RS06295	COG0583	DNA-binding transcription factor activity
EJN92_RS06330	COG0535	radical SAM domain protein
EJN92_RS06350	COG3391	amine dehydrogenase activity
EJN92_RS06360	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EJN92_RS06360	COG1648	precorrin-2 dehydrogenase activity
EJN92_RS06390	COG2249	NAD(P)H dehydrogenase (quinone) activity
EJN92_RS06400	COG0545	Peptidyl-prolyl cis-trans isomerase
EJN92_RS06445	COG2363	Small membrane protein
EJN92_RS06455	COG0840	transmembrane signaling receptor activity
EJN92_RS06460	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EJN92_RS06470	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EJN92_RS06480	COG0523	cobalamin synthesis protein
EJN92_RS06495	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EJN92_RS06500	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EJN92_RS06515	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EJN92_RS06525	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
EJN92_RS06535	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EJN92_RS06540	COG0588	phosphoglycerate mutase activity
EJN92_RS06545	COG4942	peptidase
EJN92_RS06550	COG0793	Belongs to the peptidase S41A family
EJN92_RS06570	COG4206	TonB-dependent receptor
EJN92_RS06575	COG0512	Glutamine amidotransferase of anthranilate synthase
EJN92_RS06575	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EJN92_RS06595	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EJN92_RS06600	COG1595	DNA-templated transcription, initiation
EJN92_RS06620	COG2823	Periplasmic or secreted lipoprotein
EJN92_RS06625	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
EJN92_RS06630	COG0792	nuclease activity
EJN92_RS06640	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EJN92_RS06645	COG0772	Belongs to the SEDS family
EJN92_RS06650	COG0768	penicillin binding
EJN92_RS06660	COG1792	Involved in formation and maintenance of cell shape
EJN92_RS06665	COG1077	Cell shape determining protein MreB Mrl
EJN92_RS06670	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EJN92_RS06675	COG0154	amidase activity
EJN92_RS06685	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EJN92_RS06690	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EJN92_RS06700	COG0840	transmembrane signaling receptor activity
EJN92_RS06755	COG1091	dTDP-4-dehydrorhamnose reductase activity
EJN92_RS06820	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
EJN92_RS06850	COG1028	Short-chain dehydrogenase reductase Sdr
EJN92_RS06860	COG0277	FAD linked oxidase domain protein
EJN92_RS06870	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EJN92_RS06880	COG0708	Exodeoxyribonuclease III
EJN92_RS06885	COG0737	Belongs to the 5'-nucleotidase family
EJN92_RS06895	COG0501	Belongs to the peptidase M48B family
EJN92_RS06900	COG2814	Major facilitator Superfamily
EJN92_RS06905	COG2813	Specifically methylates the guanine in position
EJN92_RS06905	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EJN92_RS06910	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EJN92_RS06920	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EJN92_RS06925	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EJN92_RS06935	COG0189	ligase activity
EJN92_RS06945	COG2329	Antibiotic biosynthesis monooxygenase
EJN92_RS06955	COG3788	relative of glutathione S-transferase, MAPEG superfamily
EJN92_RS07020	COG0596	Alpha beta hydrolase
EJN92_RS07040	COG0604	alcohol dehydrogenase
EJN92_RS07045	COG1309	transcriptional regulator
EJN92_RS07070	COG1024	Enoyl-CoA hydratase
EJN92_RS07085	COG0693	protein deglycase activity
EJN92_RS07090	COG4206	TonB-dependent receptor
EJN92_RS07140	COG4628	conserved protein (DUF2132)
EJN92_RS07145	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EJN92_RS07155	COG0583	DNA-binding transcription factor activity
EJN92_RS07160	COG0583	DNA-binding transcription factor activity
EJN92_RS07170	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EJN92_RS07170	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EJN92_RS07170	COG1703	isobutyryl-CoA mutase activity
EJN92_RS07185	COG4372	Transposase
EJN92_RS07235	COG2824	Alkylphosphonate utilization operon protein PhnA
EJN92_RS07250	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EJN92_RS07255	COG1477	protein flavinylation
EJN92_RS07300	COG1476	TRANSCRIPTIONal
EJN92_RS07310	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EJN92_RS07330	COG3766	membrane
EJN92_RS07335	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EJN92_RS07340	COG3976	FMN-binding domain protein
EJN92_RS07340	COG0431	NADPH-dependent FMN reductase
EJN92_RS07340	COG1053	succinate dehydrogenase
EJN92_RS07350	COG4574	serine-type endopeptidase inhibitor activity
EJN92_RS07365	COG2354	Protein conserved in bacteria
EJN92_RS07370	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EJN92_RS07385	COG0037	tRNA processing
EJN92_RS07395	COG1028	Short-chain dehydrogenase reductase Sdr
EJN92_RS07420	COG1280	lysine exporter protein (LysE YggA)
EJN92_RS07430	COG1393	Belongs to the ArsC family
EJN92_RS07435	COG2119	membrane
EJN92_RS07450	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EJN92_RS07510	COG0583	DNA-binding transcription factor activity
EJN92_RS07525	COG0402	S-adenosylhomocysteine deaminase activity
EJN92_RS07535	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EJN92_RS07545	COG3845	ABC transporter
EJN92_RS07550	COG4603	Belongs to the binding-protein-dependent transport system permease family
EJN92_RS07575	COG3437	response regulator, receiver
EJN92_RS07575	COG0784	Response regulator, receiver
EJN92_RS07585	COG2015	COG2015, Alkyl sulfatase and related hydrolases
EJN92_RS07595	COG1793	dna ligase
EJN92_RS07605	COG1309	transcriptional regulator
EJN92_RS07620	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EJN92_RS07640	COG0300	oxidoreductase activity
EJN92_RS07660	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EJN92_RS07665	COG4452	Inner membrane protein CreD
EJN92_RS07675	COG2205	protein histidine kinase activity
EJN92_RS07680	COG0745	RESPONSE REGULATOR receiver
EJN92_RS07745	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EJN92_RS07750	COG1595	DNA-templated transcription, initiation
EJN92_RS07760	COG1473	amidohydrolase
EJN92_RS07765	COG0840	transmembrane signaling receptor activity
EJN92_RS07780	COG0606	chelatase, subunit chli
EJN92_RS07795	COG0347	Belongs to the P(II) protein family
EJN92_RS07800	COG0004	ammonium transporteR
EJN92_RS07805	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EJN92_RS07840	COG5001	Diguanylate cyclase
EJN92_RS07845	COG1803	Methylglyoxal synthase
EJN92_RS07865	COG2059	Chromate
EJN92_RS07915	COG4555	ABC transporter
EJN92_RS07930	COG2226	methyltransferase
EJN92_RS07960	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
EJN92_RS08035	COG2205	protein histidine kinase activity
EJN92_RS08055	COG0443	Heat shock 70 kDa protein
EJN92_RS08060	COG1253	flavin adenine dinucleotide binding
EJN92_RS08065	COG1301	dicarboxylic acid transport
EJN92_RS08070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EJN92_RS08100	COG1773	rubredoxin
EJN92_RS08105	COG3239	Fatty acid desaturase
EJN92_RS08135	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
EJN92_RS08150	COG0071	Belongs to the small heat shock protein (HSP20) family
EJN92_RS08155	COG1435	thymidine kinase activity
EJN92_RS08180	COG0697	spore germination
EJN92_RS08185	COG1335	isochorismatase
EJN92_RS08190	COG4977	sequence-specific DNA binding
EJN92_RS08250	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EJN92_RS08255	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EJN92_RS08260	COG0156	8-amino-7-oxononanoate synthase activity
EJN92_RS08280	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EJN92_RS08285	COG3012	SEC-C Motif Domain Protein
EJN92_RS08300	COG1960	acyl-CoA dehydrogenase activity
EJN92_RS08305	COG1028	Short-chain dehydrogenase reductase Sdr
EJN92_RS08310	COG0183	Belongs to the thiolase family
EJN92_RS08315	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
EJN92_RS08320	COG1960	acyl-CoA dehydrogenase activity
EJN92_RS08330	COG0789	Transcriptional regulator
EJN92_RS08340	COG0697	spore germination
EJN92_RS08350	COG0840	transmembrane signaling receptor activity
EJN92_RS08360	COG2201	protein-glutamate methylesterase activity
EJN92_RS08370	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EJN92_RS08375	COG0300	oxidoreductase activity
EJN92_RS08380	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EJN92_RS08390	COG0018	arginyl-trna synthetase
EJN92_RS08395	COG2974	May be involved in recombination
EJN92_RS08440	COG2201	protein-glutamate methylesterase activity
EJN92_RS08445	COG3104	oligopeptide transport
EJN92_RS08450	COG0183	Belongs to the thiolase family
EJN92_RS08460	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EJN92_RS08470	COG2271	Major facilitator Superfamily
EJN92_RS08475	COG0339	signal peptide processing
EJN92_RS08485	COG0840	transmembrane signaling receptor activity
EJN92_RS08500	COG1902	pentaerythritol trinitrate reductase activity
EJN92_RS08500	COG0446	pyridine nucleotide-disulphide oxidoreductase
EJN92_RS08520	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EJN92_RS08530	COG5002	protein histidine kinase activity
EJN92_RS08550	COG0604	alcohol dehydrogenase
EJN92_RS08555	COG0583	DNA-binding transcription factor activity
EJN92_RS08575	COG0612	Peptidase, M16
EJN92_RS08580	COG0676	glucose-6-phosphate 1-epimerase activity
EJN92_RS08590	COG3264	Mechanosensitive ion channel
EJN92_RS08590	COG1196	nuclear chromosome segregation
EJN92_RS08620	COG0210	DNA helicase
EJN92_RS08680	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EJN92_RS08685	COG1028	Short-chain dehydrogenase reductase Sdr
EJN92_RS08720	COG0824	Thioesterase
EJN92_RS08725	COG2986	histidine ammonia-lyase
EJN92_RS08755	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EJN92_RS08760	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EJN92_RS08820	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
EJN92_RS08830	COG3706	GGDEF domain
EJN92_RS08835	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EJN92_RS08850	COG1028	Short-chain dehydrogenase reductase Sdr
EJN92_RS08855	COG0583	DNA-binding transcription factor activity
EJN92_RS08870	COG1028	Short-chain dehydrogenase reductase Sdr
EJN92_RS08895	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EJN92_RS08900	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EJN92_RS08905	COG2326	polyphosphate kinase activity
EJN92_RS08915	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EJN92_RS08920	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EJN92_RS08925	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EJN92_RS08930	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EJN92_RS08935	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EJN92_RS08940	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EJN92_RS08950	COG0356	it plays a direct role in the translocation of protons across the membrane
EJN92_RS08965	COG1475	DNA binding
EJN92_RS08970	COG1192	Involved in chromosome partitioning
EJN92_RS08975	COG0357	Ribosomal RNA small subunit methyltransferase G
EJN92_RS08980	COG0445	tRNA wobble uridine modification
EJN92_RS08985	COG0730	response to heat
EJN92_RS08990	COG1454	alcohol dehydrogenase
EJN92_RS09015	COG0411	ABC transporter
EJN92_RS09020	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
EJN92_RS09025	COG2070	2-Nitropropane dioxygenase
EJN92_RS09030	COG0840	transmembrane signaling receptor activity
EJN92_RS09050	COG1451	nucleotide metabolic process
EJN92_RS09055	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EJN92_RS09090	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EJN92_RS09095	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
EJN92_RS09120	COG0307	riboflavin synthase, alpha
EJN92_RS09145	COG4774	siderophore transport
EJN92_RS09160	COG0662	Cupin 2, conserved barrel domain protein
EJN92_RS09165	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EJN92_RS09185	COG3437	response regulator, receiver
EJN92_RS09185	COG0784	Response regulator, receiver
EJN92_RS09190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EJN92_RS09190	COG4191	Histidine kinase
EJN92_RS09195	COG1522	sequence-specific DNA binding
EJN92_RS09200	COG0506	proline dehydrogenase activity
EJN92_RS09200	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EJN92_RS09200	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EJN92_RS09220	COG0583	DNA-binding transcription factor activity
EJN92_RS09255	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EJN92_RS09260	COG3148	PFAM DTW domain containing protein
EJN92_RS09265	COG0840	transmembrane signaling receptor activity
EJN92_RS09275	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EJN92_RS09285	COG0121	glutamine amidotransferase
EJN92_RS09310	COG0861	Integral membrane protein TerC family
EJN92_RS09315	COG0670	Belongs to the BI1 family
EJN92_RS09320	COG0583	DNA-binding transcription factor activity
EJN92_RS09325	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EJN92_RS09330	COG0242	peptide deformylase activity
EJN92_RS09340	COG0758	DNA mediated transformation
EJN92_RS09345	COG2922	Belongs to the Smg family
EJN92_RS09350	COG0551	DNA topoisomerase type I activity
EJN92_RS09350	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EJN92_RS09390	COG2972	Histidine kinase
EJN92_RS09395	COG3279	Response regulator of the LytR AlgR family
EJN92_RS09410	COG3591	Belongs to the peptidase S1B family
EJN92_RS09410	COG4990	cell redox homeostasis
EJN92_RS09455	COG3279	Response regulator of the LytR AlgR family
EJN92_RS09460	COG3275	phosphorelay sensor kinase activity
EJN92_RS09475	COG0697	spore germination
EJN92_RS09490	COG3047	cAMP biosynthetic process
EJN92_RS09495	COG0488	(ABC) transporter
EJN92_RS09505	COG1739	Uncharacterized protein family UPF0029
EJN92_RS09515	COG0438	transferase activity, transferring glycosyl groups
EJN92_RS09520	COG0367	asparagine synthase
EJN92_RS09530	COG0438	transferase activity, transferring glycosyl groups
EJN92_RS09600	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EJN92_RS09640	COG3409	Peptidoglycan-binding domain 1 protein
EJN92_RS09640	COG3267	Type II secretory pathway component ExeA
EJN92_RS09650	COG0489	protein tyrosine kinase activity
EJN92_RS09675	COG3547	Transposase (IS116 IS110 IS902 family)
EJN92_RS09685	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EJN92_RS09690	COG1960	acyl-CoA dehydrogenase activity
EJN92_RS09740	COG3842	ATPase activity
EJN92_RS09745	COG2366	antibiotic biosynthetic process
EJN92_RS09760	COG0625	glutathione transferase activity
EJN92_RS09770	COG0640	Transcriptional regulator
EJN92_RS09790	COG3210	domain, Protein
EJN92_RS09795	COG2831	hemolysin activation secretion protein
EJN92_RS09850	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EJN92_RS09920	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EJN92_RS09940	COG0697	spore germination
EJN92_RS09955	COG3275	phosphorelay sensor kinase activity
EJN92_RS09990	COG5000	phosphorelay sensor kinase activity
EJN92_RS09995	COG2204	response regulator
EJN92_RS09995	COG2204	response regulator
EJN92_RS10010	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EJN92_RS10035	COG1573	uracil-dna glycosylase
EJN92_RS10050	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EJN92_RS10085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EJN92_RS10115	COG2897	thiosulfate sulfurtransferase activity
EJN92_RS10140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EJN92_RS10150	COG3258	Cytochrome c
EJN92_RS10180	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EJN92_RS10255	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EJN92_RS10260	COG1280	lysine exporter protein (LysE YggA)
EJN92_RS10270	COG1253	flavin adenine dinucleotide binding
EJN92_RS10295	COG0617	tRNA 3'-terminal CCA addition
EJN92_RS10295	COG0517	IMP dehydrogenase activity
EJN92_RS10295	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EJN92_RS10300	COG1741	Belongs to the pirin family
EJN92_RS10310	COG3511	phospholipase C
EJN92_RS10350	COG0583	DNA-binding transcription factor activity
EJN92_RS10380	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
EJN92_RS10385	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
EJN92_RS10400	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EJN92_RS10405	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EJN92_RS10410	COG0594	ribonuclease P activity
EJN92_RS10415	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EJN92_RS10420	COG0706	membrane insertase activity
EJN92_RS10425	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EJN92_RS10510	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EJN92_RS10515	COG4191	Histidine kinase
EJN92_RS10520	COG2204	response regulator
EJN92_RS10545	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EJN92_RS10555	COG0457	Tetratricopeptide repeat
EJN92_RS10560	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EJN92_RS10580	COG3384	dioxygenase
EJN92_RS10605	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EJN92_RS10610	COG1959	2 iron, 2 sulfur cluster binding
EJN92_RS10645	COG2205	protein histidine kinase activity
EJN92_RS10665	COG0583	DNA-binding transcription factor activity
EJN92_RS10690	COG1840	ABC-type Fe3 transport system, periplasmic component
EJN92_RS10700	COG3842	ATPase activity
EJN92_RS10705	COG4149	molybdate abc transporter
EJN92_RS10710	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EJN92_RS10725	COG2188	Transcriptional regulator
EJN92_RS10745	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EJN92_RS10780	COG1522	sequence-specific DNA binding
EJN92_RS10795	COG2223	nitrite transmembrane transporter activity
EJN92_RS10800	COG0243	molybdopterin cofactor binding
EJN92_RS10805	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EJN92_RS10825	COG2815	serine threonine protein kinase
EJN92_RS10825	COG0515	serine threonine protein kinase
EJN92_RS10835	COG2918	glutathione biosynthetic process
EJN92_RS10880	COG0741	lytic transglycosylase activity
EJN92_RS10890	COG2900	Belongs to the SlyX family
EJN92_RS10900	COG0840	transmembrane signaling receptor activity
EJN92_RS10920	COG0686	Belongs to the AlaDH PNT family
EJN92_RS11005	COG2205	protein histidine kinase activity
EJN92_RS11040	COG4566	intracellular signal transduction
EJN92_RS11065	COG0395	ABC-type sugar transport system, permease component
EJN92_RS11080	COG4771	TonB-dependent receptor
EJN92_RS11110	COG0183	Belongs to the thiolase family
EJN92_RS11120	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EJN92_RS11130	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EJN92_RS11140	COG4191	Histidine kinase
EJN92_RS11145	COG0038	chloride channel
EJN92_RS11165	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EJN92_RS11170	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
EJN92_RS11175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EJN92_RS11185	COG3132	Protein of unknown function, DUF480
EJN92_RS11225	COG4206	TonB-dependent receptor
EJN92_RS11245	COG0583	DNA-binding transcription factor activity
EJN92_RS11250	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EJN92_RS11255	COG4208	sulfate ABC transporter
EJN92_RS11270	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EJN92_RS11290	COG2271	Major facilitator Superfamily
EJN92_RS11305	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EJN92_RS11320	COG0348	domain, Protein
EJN92_RS11320	COG3901	Regulator of nitric oxide reductase transcription
EJN92_RS11325	COG4263	nitrous-oxide reductase activity
EJN92_RS11330	COG3245	cytochrome
EJN92_RS11340	COG3706	GGDEF domain
EJN92_RS11340	COG2203	Gaf domain
EJN92_RS11340	COG4251	negative regulation of phosphorylation
EJN92_RS11340	COG5001	Diguanylate cyclase
EJN92_RS11395	COG1136	(ABC) transporter
EJN92_RS11440	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EJN92_RS11460	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EJN92_RS11465	COG0081	regulation of translation
EJN92_RS11470	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EJN92_RS11475	COG0222	ribosome binding
EJN92_RS11480	COG0085	RNA polymerase activity
EJN92_RS11485	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EJN92_RS11495	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EJN92_RS11525	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EJN92_RS11535	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EJN92_RS11585	COG2124	cytochrome p450
EJN92_RS11590	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EJN92_RS11605	COG3108	Peptidase M15
EJN92_RS11610	COG0205	6-phosphofructokinase activity
EJN92_RS11630	COG0019	diaminopimelate decarboxylase activity
EJN92_RS11635	COG1522	sequence-specific DNA binding
EJN92_RS11645	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EJN92_RS11650	COG0431	NADPH-dependent FMN reductase
EJN92_RS11670	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EJN92_RS11675	COG5002	protein histidine kinase activity
EJN92_RS11690	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EJN92_RS11710	COG0657	acetylesterase activity
EJN92_RS11755	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
EJN92_RS11760	COG3454	Phosphonate metabolism
EJN92_RS11790	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EJN92_RS11830	COG0446	pyridine nucleotide-disulphide oxidoreductase
EJN92_RS11830	COG1902	pentaerythritol trinitrate reductase activity
EJN92_RS11845	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EJN92_RS11860	COG2201	protein-glutamate methylesterase activity
EJN92_RS11865	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
EJN92_RS11880	COG0840	transmembrane signaling receptor activity
EJN92_RS11885	COG0643	Histidine kinase
EJN92_RS11885	COG2198	Histidine kinase
EJN92_RS11900	COG0840	transmembrane signaling receptor activity
EJN92_RS11915	COG1040	competence protein
EJN92_RS11920	COG2226	methyltransferase
EJN92_RS11925	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EJN92_RS11930	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EJN92_RS11935	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
EJN92_RS11965	COG1612	heme a metabolic process
EJN92_RS11970	COG0109	protoheme IX farnesyltransferase activity
EJN92_RS11975	COG1999	signal sequence binding
EJN92_RS11980	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EJN92_RS11985	COG2177	Part of the ABC transporter FtsEX involved in
EJN92_RS11990	COG2884	Cell division ATP-binding protein ftsE
EJN92_RS12000	COG0742	ribosomal rna small subunit methyltransferase
EJN92_RS12005	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EJN92_RS12010	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EJN92_RS12020	COG0633	Ferredoxin
EJN92_RS12020	COG3217	Mosc domain protein beta barrel domain protein
EJN92_RS12030	COG0012	GTP binding
EJN92_RS12065	COG0193	aminoacyl-tRNA hydrolase activity
EJN92_RS12075	COG2814	Major facilitator Superfamily
EJN92_RS12080	COG0629	single-stranded DNA binding
EJN92_RS12090	COG0840	transmembrane signaling receptor activity
EJN92_RS12100	COG0069	glutamate synthase activity
EJN92_RS12100	COG0067	glutamate synthase
EJN92_RS12100	COG0070	glutamate synthase
EJN92_RS12110	COG1127	ABC transporter
EJN92_RS12115	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EJN92_RS12120	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EJN92_RS12140	COG1131	(ABC) transporter
EJN92_RS12145	COG0842	Transport permease protein
EJN92_RS12150	COG0271	Belongs to the BolA IbaG family
EJN92_RS12155	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EJN92_RS12160	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EJN92_RS12165	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EJN92_RS12175	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EJN92_RS12180	COG0131	Imidazoleglycerol-phosphate dehydratase
EJN92_RS12190	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EJN92_RS12195	COG0107	imidazoleglycerol-phosphate synthase activity
EJN92_RS12200	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EJN92_RS12205	COG0140	phosphoribosyl-ATP diphosphatase activity
EJN92_RS12215	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EJN92_RS12220	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EJN92_RS12225	COG0805	protein transport
EJN92_RS12240	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EJN92_RS12245	COG1970	mechanosensitive ion channel activity
EJN92_RS12250	COG0723	plastoquinol--plastocyanin reductase activity
EJN92_RS12255	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EJN92_RS12260	COG2857	Cytochrome c1
EJN92_RS12265	COG0625	glutathione transferase activity
EJN92_RS12270	COG2969	positive regulation of protein catabolic process
EJN92_RS12305	COG0163	prenyltransferase activity
EJN92_RS12310	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EJN92_RS12315	COG2183	response to ionizing radiation
EJN92_RS12335	COG2890	protein-(glutamine-N5) methyltransferase activity
EJN92_RS12340	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
EJN92_RS12345	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EJN92_RS12350	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EJN92_RS12355	COG2205	protein histidine kinase activity
EJN92_RS12355	COG2198	Histidine kinase
EJN92_RS12355	COG0784	Response regulator, receiver
EJN92_RS12355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EJN92_RS12370	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
EJN92_RS12380	COG0850	regulation of cytokinetic process
EJN92_RS12390	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EJN92_RS12395	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EJN92_RS12415	COG0134	indole-3-glycerol-phosphate synthase activity
EJN92_RS12420	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EJN92_RS12435	COG0546	phosphoglycolate phosphatase activity
EJN92_RS12440	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EJN92_RS12445	COG2967	ApaG domain
EJN92_RS12450	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
EJN92_RS12455	COG1024	Enoyl-CoA hydratase
EJN92_RS12485	COG2084	Dehydrogenase
EJN92_RS12490	COG0243	molybdopterin cofactor binding
EJN92_RS12495	COG0318	PFAM AMP-dependent synthetase and ligase
EJN92_RS12500	COG0318	PFAM AMP-dependent synthetase and ligase
EJN92_RS12505	COG1660	Displays ATPase and GTPase activities
EJN92_RS12510	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EJN92_RS12520	COG5001	Diguanylate cyclase
EJN92_RS12530	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EJN92_RS12530	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EJN92_RS12535	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EJN92_RS12540	COG1238	metal cluster binding
EJN92_RS12560	COG2226	methyltransferase
EJN92_RS12575	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EJN92_RS12580	COG0500	methyltransferase
EJN92_RS12590	COG1715	Restriction endonuclease
EJN92_RS12605	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EJN92_RS12610	COG1984	allophanate hydrolase subunit 2
EJN92_RS12615	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EJN92_RS12630	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EJN92_RS12635	COG2205	protein histidine kinase activity
EJN92_RS12655	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EJN92_RS12660	COG0494	nUDIX hydrolase
EJN92_RS12665	COG3568	Endonuclease Exonuclease Phosphatase
EJN92_RS12675	COG5002	protein histidine kinase activity
EJN92_RS12690	COG1960	acyl-CoA dehydrogenase activity
EJN92_RS12695	COG1250	3-hydroxyacyl-CoA dehydrogenase
EJN92_RS12695	COG1024	Enoyl-CoA hydratase
EJN92_RS12700	COG0183	Belongs to the thiolase family
EJN92_RS12710	COG1024	Enoyl-CoA hydratase
EJN92_RS12730	COG2001	Belongs to the MraZ family
EJN92_RS12735	COG0275	rRNA processing
EJN92_RS12750	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EJN92_RS12755	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EJN92_RS12760	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EJN92_RS12775	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EJN92_RS12780	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EJN92_RS12785	COG1181	Belongs to the D-alanine--D-alanine ligase family
EJN92_RS12790	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EJN92_RS12800	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EJN92_RS12805	COG0678	peroxiredoxin activity
EJN92_RS12820	COG0739	heme binding
EJN92_RS12820	COG0741	lytic transglycosylase activity
EJN92_RS12820	COG1196	nuclear chromosome segregation
EJN92_RS12825	COG0653	protein targeting
EJN92_RS12840	COG1846	Transcriptional regulator
EJN92_RS12845	COG2353	YceI-like domain
EJN92_RS12855	COG3038	cytochrome b561
EJN92_RS12900	COG0688	phosphatidylethanolamine metabolic process
EJN92_RS12915	COG0450	alkyl hydroperoxide reductase
EJN92_RS12920	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EJN92_RS12930	COG0482	sulfurtransferase activity
EJN92_RS12945	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EJN92_RS12965	COG0494	nUDIX hydrolase
EJN92_RS12970	COG0442	prolyl-tRNA aminoacylation
EJN92_RS12975	COG0741	lytic transglycosylase activity
EJN92_RS12990	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EJN92_RS13005	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EJN92_RS13020	COG2204	response regulator
EJN92_RS13030	COG1607	acyl-coa hydrolase
EJN92_RS13035	COG5265	(ABC) transporter
EJN92_RS13040	COG0683	leucine binding
EJN92_RS13050	COG2902	Dehydrogenase
EJN92_RS13065	COG0765	amino acid transport
EJN92_RS13070	COG0765	amino acid transport
EJN92_RS13075	COG1126	abc transporter atp-binding protein
EJN92_RS13080	COG0418	dihydroorotase activity
EJN92_RS13100	COG0525	valine-tRNA ligase activity
EJN92_RS13105	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EJN92_RS13125	COG3023	N-Acetylmuramoyl-L-alanine amidase
EJN92_RS13135	COG0612	Peptidase, M16
EJN92_RS13140	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EJN92_RS13145	COG0741	lytic transglycosylase activity
EJN92_RS13155	COG0617	tRNA 3'-terminal CCA addition
EJN92_RS13175	COG1944	ATP diphosphatase activity
EJN92_RS13185	COG3483	tryptophan 2,3-dioxygenase activity
EJN92_RS13195	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
EJN92_RS13200	COG1522	sequence-specific DNA binding
EJN92_RS13205	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EJN92_RS13210	COG2850	peptidyl-arginine hydroxylation
EJN92_RS13220	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EJN92_RS13225	COG0138	bifunctional purine biosynthesis protein purh
EJN92_RS13230	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
EJN92_RS13235	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EJN92_RS13240	COG1252	NADH dehydrogenase
EJN92_RS13250	COG0406	alpha-ribazole phosphatase activity
EJN92_RS13255	COG1490	D-aminoacyl-tRNA deacylase activity
EJN92_RS13265	COG0739	heme binding
EJN92_RS13280	COG0436	Aminotransferase
EJN92_RS13285	COG4989	oxidoreductase activity
EJN92_RS13295	COG0583	DNA-binding transcription factor activity
EJN92_RS13300	COG2096	Adenosyltransferase
EJN92_RS13305	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EJN92_RS13310	COG0142	geranyltranstransferase activity
EJN92_RS13315	COG1722	exodeoxyribonuclease VII activity
EJN92_RS13325	COG5380	lipid catabolic process
EJN92_RS13330	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
EJN92_RS13355	COG0386	Belongs to the glutathione peroxidase family
EJN92_RS13390	COG4575	ribosome binding
EJN92_RS13395	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EJN92_RS13410	COG1028	Short-chain dehydrogenase reductase Sdr
EJN92_RS13425	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EJN92_RS13430	COG0343	queuine tRNA-ribosyltransferase activity
EJN92_RS13435	COG1862	Preprotein translocase
EJN92_RS13445	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EJN92_RS13450	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EJN92_RS13480	COG1573	uracil-dna glycosylase
EJN92_RS13495	COG2207	Transcriptional regulator
EJN92_RS13520	COG4372	Transposase
EJN92_RS13525	COG3253	May function as heme-dependent peroxidase
EJN92_RS13530	COG0583	DNA-binding transcription factor activity
EJN92_RS13585	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EJN92_RS13590	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EJN92_RS13605	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
EJN92_RS13610	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
EJN92_RS13635	COG0142	geranyltranstransferase activity
EJN92_RS13645	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EJN92_RS13650	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EJN92_RS13655	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EJN92_RS13660	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EJN92_RS13665	COG0006	proline dipeptidase activity
EJN92_RS13680	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
EJN92_RS13685	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EJN92_RS13690	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EJN92_RS13695	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EJN92_RS13700	COG0166	Belongs to the GPI family
EJN92_RS13705	COG4221	oxidoreductase activity
EJN92_RS13710	COG0824	Thioesterase
EJN92_RS13740	COG0823	Involved in the tonB-independent uptake of proteins
EJN92_RS13745	COG2885	chlorophyll binding
EJN92_RS13770	COG0248	Ppx GppA phosphatase
EJN92_RS13785	COG2010	Cytochrome c
EJN92_RS13785	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EJN92_RS13800	COG4191	Histidine kinase
EJN92_RS13800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EJN92_RS13805	COG0840	transmembrane signaling receptor activity
EJN92_RS13810	COG4181	ATPase activity
EJN92_RS13815	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
EJN92_RS13835	COG5002	protein histidine kinase activity
EJN92_RS13840	COG3813	Protein conserved in bacteria
EJN92_RS13850	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EJN92_RS13860	COG2423	ornithine cyclodeaminase activity
EJN92_RS13865	COG1522	sequence-specific DNA binding
EJN92_RS13870	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EJN92_RS13880	COG3135	benzoate transporter
EJN92_RS13885	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EJN92_RS13890	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EJN92_RS13890	COG2111	Na H antiporter
EJN92_RS13895	COG1006	Multisubunit Na H antiporter MnhC subunit
EJN92_RS13900	COG0651	ATP synthesis coupled electron transport
EJN92_RS13905	COG1863	multisubunit Na H antiporter MnhE subunit
EJN92_RS13910	COG2212	antiporter activity
EJN92_RS13915	COG1320	monovalent cation:proton antiporter activity
EJN92_RS13920	COG2027	D-alanyl-D-alanine carboxypeptidase
EJN92_RS13930	COG0546	phosphoglycolate phosphatase activity
EJN92_RS13935	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EJN92_RS13950	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EJN92_RS13955	COG0077	Prephenate dehydratase
EJN92_RS13955	COG1605	Chorismate mutase
EJN92_RS13960	COG0287	Prephenate dehydrogenase
EJN92_RS13965	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EJN92_RS13970	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EJN92_RS13980	COG0776	regulation of translation
EJN92_RS13990	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
EJN92_RS14000	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
EJN92_RS14020	COG2766	serine protein kinase
EJN92_RS14025	COG2718	Belongs to the UPF0229 family
EJN92_RS14030	COG2719	SpoVR family
EJN92_RS14045	COG0789	Transcriptional regulator
EJN92_RS14055	COG0531	amino acid
EJN92_RS14060	COG3045	CreA protein
EJN92_RS14085	COG1649	PFAM Uncharacterised BCR, COG1649
EJN92_RS14100	COG1178	ABC-type Fe3 transport system permease component
EJN92_RS14105	COG3842	ATPase activity
EJN92_RS14110	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EJN92_RS14155	COG1881	PFAM PEBP family protein
EJN92_RS14210	COG0577	efflux transmembrane transporter activity
EJN92_RS14215	COG1136	(ABC) transporter
EJN92_RS14250	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EJN92_RS14270	COG3128	pkhd-type hydroxylase
EJN92_RS14300	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EJN92_RS14310	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EJN92_RS14315	COG0443	Heat shock 70 kDa protein
EJN92_RS14320	COG0484	heat shock protein binding
EJN92_RS14325	COG0489	protein tyrosine kinase activity
EJN92_RS14330	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EJN92_RS14330	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EJN92_RS14345	COG0564	pseudouridine synthase activity
EJN92_RS14375	COG0243	molybdopterin cofactor binding
EJN92_RS14375	COG3383	formate dehydrogenase (NAD+) activity
EJN92_RS14380	COG0437	4 iron, 4 sulfur cluster binding
EJN92_RS14390	COG2864	formate dehydrogenase
EJN92_RS14400	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EJN92_RS14405	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EJN92_RS14435	COG0328	RNA-DNA hybrid ribonuclease activity
EJN92_RS14440	COG2226	methyltransferase
EJN92_RS14445	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EJN92_RS14455	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EJN92_RS14465	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EJN92_RS14470	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EJN92_RS14475	COG1136	(ABC) transporter
EJN92_RS14480	COG1136	(ABC) transporter
EJN92_RS14480	COG0577	efflux transmembrane transporter activity
EJN92_RS14485	COG0577	efflux transmembrane transporter activity
EJN92_RS14505	COG1079	Belongs to the binding-protein-dependent transport system permease family
EJN92_RS14510	COG4603	Belongs to the binding-protein-dependent transport system permease family
EJN92_RS14515	COG3845	ABC transporter
EJN92_RS14520	COG1744	ABC transporter substrate-binding protein PnrA-like
EJN92_RS14525	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EJN92_RS14535	COG2264	protein methyltransferase activity
EJN92_RS14540	COG0439	Biotin carboxylase
EJN92_RS14545	COG0511	ligase activity, forming carbon-carbon bonds
EJN92_RS14550	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EJN92_RS14555	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EJN92_RS14565	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EJN92_RS14570	COG3150	esterase
EJN92_RS14575	COG3161	chorismate lyase activity
EJN92_RS14580	COG0557	exoribonuclease II activity
EJN92_RS14590	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EJN92_RS14595	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EJN92_RS14605	COG0598	Magnesium transport protein CorA
EJN92_RS14610	COG2274	protein secretion by the type I secretion system
EJN92_RS14615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EJN92_RS14630	COG3622	Belongs to the hyi family
EJN92_RS14635	COG2200	EAL domain
EJN92_RS14650	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EJN92_RS14655	COG0351	phosphomethylpyrimidine kinase
EJN92_RS14660	COG1773	rubredoxin
EJN92_RS14680	COG0840	transmembrane signaling receptor activity
EJN92_RS14685	COG2198	Histidine kinase
EJN92_RS14685	COG0643	Histidine kinase
EJN92_RS14685	COG0643	Histidine kinase
EJN92_RS14685	COG2198	Histidine kinase
EJN92_RS14690	COG0415	Belongs to the DNA photolyase family
EJN92_RS14695	COG1678	Uncharacterized ACR, COG1678
EJN92_RS14700	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EJN92_RS14705	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EJN92_RS14710	COG0540	Belongs to the ATCase OTCase family
EJN92_RS14725	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EJN92_RS14730	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EJN92_RS14735	COG0497	DNA recombination
EJN92_RS14740	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EJN92_RS14750	COG1420	regulation of RNA biosynthetic process
EJN92_RS14755	COG2201	protein-glutamate methylesterase activity
EJN92_RS14760	COG0735	belongs to the Fur family
EJN92_RS14765	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EJN92_RS14770	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EJN92_RS14785	COG0495	leucyl-tRNA aminoacylation
EJN92_RS14800	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EJN92_RS14805	COG1981	membrane
EJN92_RS14820	COG2814	Major facilitator Superfamily
EJN92_RS14825	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EJN92_RS14865	COG1960	acyl-CoA dehydrogenase activity
EJN92_RS14885	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EJN92_RS14925	COG0573	inorganic phosphate transmembrane transporter activity
EJN92_RS14935	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EJN92_RS14940	COG0704	Plays a role in the regulation of phosphate uptake
EJN92_RS14950	COG5002	protein histidine kinase activity
EJN92_RS14965	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EJN92_RS14965	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EJN92_RS14975	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EJN92_RS14980	COG3707	response regulator
EJN92_RS14985	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EJN92_RS14990	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EJN92_RS14995	COG1116	anion transmembrane transporter activity
EJN92_RS15000	COG2818	Glycosylase
EJN92_RS15020	COG0859	PFAM glycosyl transferase family 9
EJN92_RS15035	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EJN92_RS15045	COG0617	tRNA 3'-terminal CCA addition
EJN92_RS15050	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EJN92_RS15060	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EJN92_RS15065	COG4662	Binding-protein-dependent transport system inner membrane component
EJN92_RS15090	COG0288	reversible hydration of carbon dioxide
EJN92_RS15125	COG0829	nickel cation binding
EJN92_RS15130	COG0831	urea catabolic process
EJN92_RS15135	COG0832	Belongs to the urease beta subunit family
EJN92_RS15140	COG0804	urea catabolic process
EJN92_RS15145	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
EJN92_RS15150	COG0830	nickel cation binding
EJN92_RS15155	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
EJN92_RS15185	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EJN92_RS15210	COG1132	(ABC) transporter
EJN92_RS15235	COG1943	Transposase
EJN92_RS15245	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EJN92_RS15265	COG2153	protein acetylation
EJN92_RS15275	COG3275	phosphorelay sensor kinase activity
EJN92_RS15285	COG0584	glycerophosphoryl diester phosphodiesterase
EJN92_RS15295	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EJN92_RS15300	COG1247	-acetyltransferase
EJN92_RS15305	COG2816	NAD+ diphosphatase activity
EJN92_RS15310	COG0425	Belongs to the sulfur carrier protein TusA family
EJN92_RS15325	COG1960	acyl-CoA dehydrogenase activity
EJN92_RS15335	COG0228	four-way junction DNA binding
EJN92_RS15340	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EJN92_RS15345	COG0336	Belongs to the RNA methyltransferase TrmD family
EJN92_RS15350	COG0335	large ribosomal subunit rRNA binding
EJN92_RS15360	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
EJN92_RS15370	COG0193	aminoacyl-tRNA hydrolase activity
EJN92_RS15375	COG0193	aminoacyl-tRNA hydrolase activity
EJN92_RS15395	COG1960	acyl-CoA dehydrogenase activity
EJN92_RS15400	COG0318	PFAM AMP-dependent synthetase and ligase
EJN92_RS15405	COG0745	RESPONSE REGULATOR receiver
EJN92_RS15410	COG2205	protein histidine kinase activity
EJN92_RS15420	COG5001	Diguanylate cyclase
EJN92_RS15420	COG5002	protein histidine kinase activity
EJN92_RS15425	COG0596	Alpha beta hydrolase
EJN92_RS15430	COG4133	protoheme IX ABC transporter activity
EJN92_RS15435	COG2731	YhcH YjgK YiaL family protein
EJN92_RS15440	COG1704	LemA family
EJN92_RS15445	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
EJN92_RS15490	COG0616	signal peptide processing
EJN92_RS15520	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EJN92_RS15530	COG1028	Short-chain dehydrogenase reductase Sdr
EJN92_RS15570	COG2188	Transcriptional regulator
EJN92_RS15580	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EJN92_RS15595	COG0395	ABC-type sugar transport system, permease component
EJN92_RS15600	COG1472	Belongs to the glycosyl hydrolase 3 family
EJN92_RS15605	COG3842	ATPase activity
EJN92_RS15610	COG1943	Transposase
EJN92_RS15630	COG0625	glutathione transferase activity
EJN92_RS15635	COG0784	Response regulator, receiver
EJN92_RS15635	COG3437	response regulator, receiver
EJN92_RS15640	COG4191	Histidine kinase
EJN92_RS15675	COG2226	methyltransferase
EJN92_RS15700	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EJN92_RS15775	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
EJN92_RS15790	COG3842	ATPase activity
EJN92_RS15795	COG0395	ABC-type sugar transport system, permease component
EJN92_RS15800	COG1175	transmembrane transport
EJN92_RS15905	COG1309	transcriptional regulator
EJN92_RS15910	COG1979	alcohol dehydrogenase
EJN92_RS15915	COG2130	NADP-dependent
EJN92_RS15920	COG1902	pentaerythritol trinitrate reductase activity
EJN92_RS15965	COG2378	regulation of single-species biofilm formation
EJN92_RS16005	COG0625	glutathione transferase activity
EJN92_RS16020	COG0840	transmembrane signaling receptor activity
EJN92_RS16025	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EJN92_RS16045	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
EJN92_RS16050	COG2197	response regulator
EJN92_RS16055	COG0745	RESPONSE REGULATOR receiver
EJN92_RS16090	COG0811	peptide transport
EJN92_RS16125	COG1459	type II secretion system
EJN92_RS16130	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EJN92_RS16155	COG4796	Type ii and iii secretion system protein
EJN92_RS16220	COG0254	rRNA binding
EJN92_RS16225	COG2860	membrane
EJN92_RS16230	COG1309	transcriptional regulator
EJN92_RS16245	COG1538	Outer membrane efflux protein
EJN92_RS16250	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EJN92_RS16280	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EJN92_RS16285	COG0583	DNA-binding transcription factor activity
EJN92_RS16295	COG4654	Cytochrome c, class I
EJN92_RS16300	COG0683	leucine binding
EJN92_RS16320	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EJN92_RS16330	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EJN92_RS16335	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EJN92_RS16340	COG0776	regulation of translation
EJN92_RS16355	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EJN92_RS16360	COG3278	Belongs to the heme-copper respiratory oxidase family
EJN92_RS16415	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EJN92_RS16425	COG2197	response regulator
EJN92_RS16430	COG0513	Belongs to the DEAD box helicase family
EJN92_RS16455	COG0835	chemotaxis
EJN92_RS16455	COG0784	Response regulator, receiver
EJN92_RS16470	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EJN92_RS16475	COG1570	exodeoxyribonuclease VII activity
EJN92_RS16480	COG0811	peptide transport
EJN92_RS16485	COG0848	biopolymer transport protein
EJN92_RS16490	COG1663	tetraacyldisaccharide 4'-kinase activity
EJN92_RS16495	COG2835	tetraacyldisaccharide 4'-kinase activity
EJN92_RS16500	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
EJN92_RS16505	COG0563	adenylate kinase activity
EJN92_RS16535	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EJN92_RS16540	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EJN92_RS16540	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EJN92_RS16545	COG3264	Mechanosensitive ion channel
EJN92_RS16545	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
EJN92_RS16555	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EJN92_RS16560	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EJN92_RS16565	COG2003	Belongs to the UPF0758 family
EJN92_RS16570	COG1047	Peptidyl-prolyl cis-trans
EJN92_RS16575	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EJN92_RS16610	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
EJN92_RS16620	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EJN92_RS16625	COG0312	modulator of DNA gyrase
EJN92_RS16630	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EJN92_RS16640	COG1666	GTP binding
EJN92_RS16645	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EJN92_RS16655	COG3123	guanosine phosphorylase activity
EJN92_RS16660	COG0137	argininosuccinate synthase activity
EJN92_RS16665	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EJN92_RS16670	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EJN92_RS16680	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EJN92_RS16680	COG0543	2 iron, 2 sulfur cluster binding
EJN92_RS16695	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EJN92_RS16700	COG4106	trans-aconitate 2-methyltransferase activity
EJN92_RS16725	COG0556	nucleotide-excision repair
EJN92_RS16730	COG1230	cation diffusion facilitator family transporter
EJN92_RS16740	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EJN92_RS16745	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EJN92_RS16750	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EJN92_RS16755	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EJN92_RS16760	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EJN92_RS16765	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EJN92_RS16765	COG0072	phenylalanine-tRNA ligase activity
EJN92_RS16770	COG0776	regulation of translation
EJN92_RS16780	COG4535	Mg2 and Co2 transporter CorC
EJN92_RS16785	COG0815	Transfers the fatty acyl group on membrane lipoproteins
EJN92_RS16805	COG0438	transferase activity, transferring glycosyl groups
EJN92_RS16810	COG0488	(ABC) transporter
EJN92_RS16820	COG1028	Short-chain dehydrogenase reductase Sdr
EJN92_RS16825	COG0318	PFAM AMP-dependent synthetase and ligase
EJN92_RS16840	COG0284	orotidine-5'-phosphate decarboxylase activity
EJN92_RS16845	COG1546	Belongs to the CinA family
EJN92_RS16860	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EJN92_RS16895	COG0515	serine threonine protein kinase
EJN92_RS16895	COG2815	serine threonine protein kinase
EJN92_RS16900	COG2223	nitrite transmembrane transporter activity
EJN92_RS16905	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EJN92_RS16910	COG2146	nitrite reductase [NAD(P)H] activity
EJN92_RS16915	COG0243	molybdopterin cofactor binding
EJN92_RS16940	COG1297	OPT oligopeptide transporter protein
EJN92_RS16955	COG3104	oligopeptide transport
EJN92_RS16970	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EJN92_RS16975	COG0717	Belongs to the dCTP deaminase family
EJN92_RS17005	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EJN92_RS17010	COG5002	protein histidine kinase activity
EJN92_RS17015	COG2975	iron-sulfur cluster assembly
EJN92_RS17020	COG0633	Ferredoxin
EJN92_RS17025	COG0443	Heat shock 70 kDa protein
EJN92_RS17030	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EJN92_RS17035	COG0316	Belongs to the HesB IscA family
EJN92_RS17040	COG0822	iron-sulfur transferase activity
EJN92_RS17045	COG1104	cysteine desulfurase activity
EJN92_RS17060	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EJN92_RS17065	COG3300	MHYT domain
EJN92_RS17065	COG5001	Diguanylate cyclase
EJN92_RS17075	COG0582	viral genome integration into host DNA
EJN92_RS17095	COG4372	Transposase
EJN92_RS17185	COG0728	peptidoglycan biosynthetic process
EJN92_RS17190	COG0840	transmembrane signaling receptor activity
EJN92_RS17210	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EJN92_RS17215	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EJN92_RS17230	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EJN92_RS17235	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
EJN92_RS17250	COG1278	Cold shock
EJN92_RS17255	COG0840	transmembrane signaling receptor activity
EJN92_RS17260	COG0583	DNA-binding transcription factor activity
EJN92_RS17270	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EJN92_RS17275	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
EJN92_RS17280	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EJN92_RS17280	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EJN92_RS17290	COG1643	Atp-dependent helicase
EJN92_RS17310	COG0515	serine threonine protein kinase
EJN92_RS17325	COG2204	response regulator
EJN92_RS17340	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EJN92_RS17345	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EJN92_RS17350	COG0726	polysaccharide deacetylase
EJN92_RS17355	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EJN92_RS17355	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EJN92_RS17360	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EJN92_RS17360	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EJN92_RS17365	COG0463	Glycosyl transferase, family 2
EJN92_RS17370	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EJN92_RS17385	COG0436	Aminotransferase
EJN92_RS17410	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EJN92_RS17415	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EJN92_RS17430	COG1247	-acetyltransferase
EJN92_RS17435	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EJN92_RS17465	COG1187	pseudouridine synthase activity
EJN92_RS17470	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
EJN92_RS17475	COG0024	Methionine aminopeptidase
EJN92_RS17480	COG0052	Belongs to the universal ribosomal protein uS2 family
EJN92_RS17485	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EJN92_RS17490	COG0528	UMP kinase activity
EJN92_RS17495	COG0233	cytoplasmic translational termination
EJN92_RS17500	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EJN92_RS17505	COG0575	Belongs to the CDS family
EJN92_RS17510	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EJN92_RS17515	COG0750	zinc metalloprotease
EJN92_RS17530	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EJN92_RS17535	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EJN92_RS17540	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EJN92_RS17545	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EJN92_RS17550	COG0084	hydrolase, TatD family'
EJN92_RS17560	COG0395	ABC-type sugar transport system, permease component
EJN92_RS17565	COG1116	anion transmembrane transporter activity
EJN92_RS17575	COG0587	DNA-directed DNA polymerase activity
EJN92_RS17630	COG1058	Belongs to the CinA family
EJN92_RS17630	COG1546	Belongs to the CinA family
EJN92_RS17640	COG3530	Putative quorum-sensing-regulated virulence factor
EJN92_RS17660	COG3706	GGDEF domain
EJN92_RS17735	COG1752	Esterase of the alpha-beta hydrolase superfamily
EJN92_RS17745	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EJN92_RS17750	COG2986	histidine ammonia-lyase
EJN92_RS17760	COG1228	amidohydrolase
EJN92_RS17770	COG0745	RESPONSE REGULATOR receiver
EJN92_RS17795	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EJN92_RS17800	COG0268	Binds directly to 16S ribosomal RNA
EJN92_RS17830	COG1278	Cold shock
EJN92_RS17835	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EJN92_RS17840	COG0542	response to heat
EJN92_RS17850	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EJN92_RS17860	COG2866	Carboxypeptidase
EJN92_RS17865	COG2954	triphosphatase activity
EJN92_RS17885	COG1960	acyl-CoA dehydrogenase activity
EJN92_RS17895	COG0625	glutathione transferase activity
EJN92_RS17930	COG0560	Phosphoserine phosphatase
EJN92_RS17935	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EJN92_RS17940	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EJN92_RS17945	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EJN92_RS17955	COG2070	2-Nitropropane dioxygenase
EJN92_RS17970	COG0424	maF-like protein
EJN92_RS17980	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EJN92_RS17985	COG0416	fatty acid biosynthetic process
EJN92_RS17990	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EJN92_RS18000	COG1028	Short-chain dehydrogenase reductase Sdr
EJN92_RS18005	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EJN92_RS18010	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EJN92_RS18035	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EJN92_RS18045	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EJN92_RS18050	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EJN92_RS18055	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EJN92_RS18075	COG2224	Isocitrate lyase
EJN92_RS18080	COG0135	phosphoribosylanthranilate isomerase activity
EJN92_RS18085	COG0133	tryptophan synthase activity
EJN92_RS18090	COG0159	tryptophan synthase activity
EJN92_RS18095	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EJN92_RS18100	COG0285	dihydrofolate synthase activity
EJN92_RS18110	COG1286	toxin biosynthetic process
EJN92_RS18125	COG0613	PHP domain protein
EJN92_RS18130	COG0501	Belongs to the peptidase M48B family
EJN92_RS18135	COG0009	L-threonylcarbamoyladenylate synthase
EJN92_RS18140	COG1994	Peptidase M50
EJN92_RS18150	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EJN92_RS18155	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
EJN92_RS18160	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EJN92_RS18165	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EJN92_RS18175	COG2894	cell division
EJN92_RS18185	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EJN92_RS18190	COG1360	Flagellar Motor Protein
EJN92_RS18215	COG1558	bacterial-type flagellum-dependent cell motility
EJN92_RS18220	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EJN92_RS18230	COG4787	bacterial-type flagellum-dependent cell motility
EJN92_RS18240	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
EJN92_RS18245	COG1706	bacterial-type flagellum-dependent cell motility
EJN92_RS18275	COG0463	Glycosyl transferase, family 2
EJN92_RS18285	COG0047	phosphoribosylformylglycinamidine synthase activity
EJN92_RS18285	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EJN92_RS18290	COG4191	Histidine kinase
EJN92_RS18295	COG4566	intracellular signal transduction
EJN92_RS18315	COG1032	radical SAM domain protein
EJN92_RS18320	COG3291	Pkd domain containing protein
EJN92_RS18325	COG3214	Protein conserved in bacteria
EJN92_RS18335	COG0181	hydroxymethylbilane synthase activity
EJN92_RS18345	COG2959	enzyme of heme biosynthesis
EJN92_RS18355	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EJN92_RS18360	COG0515	serine threonine protein kinase
EJN92_RS18370	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EJN92_RS18370	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EJN92_RS18375	COG0347	Belongs to the P(II) protein family
EJN92_RS18385	COG2840	Smr protein MutS2
EJN92_RS18390	COG0492	ferredoxin-NADP+ reductase activity
EJN92_RS18395	COG1674	ftsk spoiiie
EJN92_RS18400	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EJN92_RS18405	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EJN92_RS18415	COG1012	belongs to the aldehyde dehydrogenase family
EJN92_RS18420	COG3290	protein histidine kinase activity
EJN92_RS18420	COG3829	transcription factor binding
EJN92_RS18440	COG4774	siderophore transport
EJN92_RS18465	COG2130	NADP-dependent
EJN92_RS18480	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EJN92_RS18505	COG2188	Transcriptional regulator
EJN92_RS18520	COG1053	succinate dehydrogenase
EJN92_RS18525	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EJN92_RS18530	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
EJN92_RS18535	COG0372	Belongs to the citrate synthase family
EJN92_RS18540	COG0567	Dehydrogenase, E1 component
EJN92_RS18545	COG0508	dehydrogenase complex catalyzes the overall conversion of
EJN92_RS18555	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EJN92_RS18560	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EJN92_RS18570	COG0436	Aminotransferase
EJN92_RS18575	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EJN92_RS18600	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EJN92_RS18605	COG2867	negative regulation of translational initiation
EJN92_RS18610	COG2914	Belongs to the UPF0125 (RnfH) family
EJN92_RS18630	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EJN92_RS18630	COG0519	Catalyzes the synthesis of GMP from XMP
EJN92_RS18635	COG0602	queuosine metabolic process
EJN92_RS18650	COG1619	proteins homologs of microcin C7 resistance protein MccF
EJN92_RS18665	COG1028	Short-chain dehydrogenase reductase Sdr
EJN92_RS18675	COG1024	Enoyl-CoA hydratase
EJN92_RS18680	COG1960	acyl-CoA dehydrogenase activity
EJN92_RS18685	COG0251	oxidation-reduction process
EJN92_RS18690	COG1215	transferase activity, transferring glycosyl groups
EJN92_RS18710	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EJN92_RS18725	COG3038	cytochrome b561
EJN92_RS18745	COG0789	Transcriptional regulator
EJN92_RS18750	COG0745	RESPONSE REGULATOR receiver
EJN92_RS18755	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EJN92_RS18765	COG2833	Protein of unknown function (DUF455)
EJN92_RS18775	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EJN92_RS18780	COG2267	carboxylic ester hydrolase activity
EJN92_RS18790	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
EJN92_RS18850	COG0303	'Molybdopterin
EJN92_RS18855	COG0746	molybdenum cofactor guanylyltransferase activity
EJN92_RS18865	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EJN92_RS18870	COG1530	ribonuclease E activity
EJN92_RS18880	COG0546	phosphoglycolate phosphatase activity
EJN92_RS18900	COG2217	Heavy metal translocating P-type atpase
EJN92_RS18910	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
EJN92_RS18920	COG4181	ATPase activity
EJN92_RS18925	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EJN92_RS18925	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EJN92_RS18935	COG1987	bacterial-type flagellum assembly
EJN92_RS18940	COG1338	Plays a role in the flagellum-specific transport system
EJN92_RS18950	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EJN92_RS18975	COG1157	protein secretion by the type III secretion system
EJN92_RS18995	COG1677	Flagellar hook-basal body complex protein FliE
EJN92_RS19000	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
EJN92_RS19005	COG2257	FlhB HrpN YscU SpaS Family
EJN92_RS19025	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EJN92_RS19060	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EJN92_RS19065	COG1758	RNA polymerase activity
EJN92_RS19075	COG1561	YicC-like family, N-terminal region
EJN92_RS19080	COG1357	PFAM Pentapeptide repeats (8 copies)
EJN92_RS19080	COG0515	serine threonine protein kinase
EJN92_RS19085	COG0631	protein serine/threonine phosphatase activity
EJN92_RS19095	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EJN92_RS19100	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EJN92_RS19105	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
EJN92_RS19120	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EJN92_RS19130	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EJN92_RS19140	COG1012	belongs to the aldehyde dehydrogenase family
EJN92_RS19150	COG1177	transmembrane transport
EJN92_RS19155	COG1176	ABC-type spermidine putrescine transport system, permease component I
EJN92_RS19160	COG3842	ATPase activity
EJN92_RS19175	COG0174	glutamine synthetase
EJN92_RS19180	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EJN92_RS19190	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EJN92_RS19195	COG1960	acyl-CoA dehydrogenase activity
EJN92_RS19200	COG0583	DNA-binding transcription factor activity
EJN92_RS19215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EJN92_RS19220	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EJN92_RS19240	COG0683	leucine binding
EJN92_RS19245	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EJN92_RS19250	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EJN92_RS19260	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EJN92_RS19295	COG1214	PFAM Peptidase M22, glycoprotease
EJN92_RS19315	COG0477	Major facilitator Superfamily
EJN92_RS19325	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EJN92_RS19330	COG1074	ATP-dependent DNA helicase activity
EJN92_RS19335	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
EJN92_RS19345	COG0326	Molecular chaperone. Has ATPase activity
EJN92_RS19370	COG0402	S-adenosylhomocysteine deaminase activity
EJN92_RS19385	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EJN92_RS19390	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EJN92_RS19395	COG0436	Aminotransferase
EJN92_RS19405	COG0583	DNA-binding transcription factor activity
EJN92_RS19415	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EJN92_RS19425	COG1752	Esterase of the alpha-beta hydrolase superfamily
EJN92_RS19430	COG0791	NLP P60 protein
EJN92_RS19435	COG0505	Belongs to the CarA family
EJN92_RS19440	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EJN92_RS19445	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EJN92_RS19455	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
EJN92_RS19460	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EJN92_RS19465	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EJN92_RS19470	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EJN92_RS19485	COG0277	FAD linked oxidase domain protein
EJN92_RS19500	COG1295	ribonuclease BN
EJN92_RS19505	COG1902	pentaerythritol trinitrate reductase activity
EJN92_RS19510	COG0488	(ABC) transporter
EJN92_RS19515	COG2890	protein-(glutamine-N5) methyltransferase activity
EJN92_RS19520	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EJN92_RS19525	COG1393	Belongs to the ArsC family
EJN92_RS19535	COG2171	N-acyltransferase activity
EJN92_RS19555	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EJN92_RS19560	COG0242	peptide deformylase activity
EJN92_RS19570	COG0084	hydrolase, TatD family'
EJN92_RS19590	COG0504	CTP synthase activity
EJN92_RS19595	COG2877	3-deoxy-8-phosphooctulonate synthase activity
EJN92_RS19600	COG0148	phosphopyruvate hydratase activity
EJN92_RS19605	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EJN92_RS19615	COG1252	NADH dehydrogenase
EJN92_RS19630	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EJN92_RS19690	COG1222	aaa ATPase
EJN92_RS19730	COG1815	bacterial-type flagellum-dependent cell motility
EJN92_RS19765	COG0789	Transcriptional regulator
EJN92_RS19770	COG0672	)-iron permease
EJN92_RS19775	COG1968	undecaprenyl-diphosphatase activity
EJN92_RS19785	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EJN92_RS19790	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EJN92_RS19795	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EJN92_RS19805	COG0431	NADPH-dependent FMN reductase
EJN92_RS19825	COG2957	Belongs to the agmatine deiminase family
EJN92_RS19830	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EJN92_RS19835	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EJN92_RS19845	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EJN92_RS19860	COG2957	Belongs to the agmatine deiminase family
EJN92_RS19890	COG1012	belongs to the aldehyde dehydrogenase family
EJN92_RS19895	COG1177	transmembrane transport
EJN92_RS19900	COG1176	ABC-type spermidine putrescine transport system, permease component I
EJN92_RS19905	COG3842	ATPase activity
EJN92_RS19915	COG0174	glutamine synthetase
EJN92_RS19925	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EJN92_RS19945	COG0583	DNA-binding transcription factor activity
EJN92_RS19950	COG4974	Belongs to the 'phage' integrase family
EJN92_RS19955	COG1022	Amp-dependent synthetase and ligase
EJN92_RS20020	COG0488	(ABC) transporter
EJN92_RS20065	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EJN92_RS20070	COG1132	(ABC) transporter
EJN92_RS20075	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
EJN92_RS20090	COG2267	carboxylic ester hydrolase activity
EJN92_RS20095	COG1280	lysine exporter protein (LysE YggA)
EJN92_RS20105	COG0596	Alpha beta hydrolase
EJN92_RS20115	COG2130	NADP-dependent
EJN92_RS20130	COG1960	acyl-CoA dehydrogenase activity
EJN92_RS20135	COG0183	Belongs to the thiolase family
EJN92_RS20140	COG0477	Major facilitator Superfamily
EJN92_RS20145	COG0697	spore germination
EJN92_RS20170	COG1396	sequence-specific DNA binding
EJN92_RS20180	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EJN92_RS20185	COG1760	l-serine dehydratase
EJN92_RS20210	COG2733	membrane
EJN92_RS20215	COG0628	permease
EJN92_RS20220	COG0110	maltose O-acetyltransferase activity
EJN92_RS20230	COG0513	Belongs to the DEAD box helicase family
EJN92_RS20235	COG1506	peptidase
EJN92_RS20235	COG0823	Involved in the tonB-independent uptake of proteins
EJN92_RS20245	COG1294	oxidase, subunit
EJN92_RS20280	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EJN92_RS20300	COG1802	Transcriptional regulator
EJN92_RS20305	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EJN92_RS20310	COG0174	glutamine synthetase
EJN92_RS20335	COG0420	3'-5' exonuclease activity
EJN92_RS20385	COG1858	cytochrome C peroxidase
EJN92_RS20395	COG4716	Myosin-crossreactive antigen
EJN92_RS20400	COG3590	peptidase
EJN92_RS20410	COG0243	molybdopterin cofactor binding
EJN92_RS20415	COG0730	response to heat
EJN92_RS20430	COG3193	protein, possibly involved in utilization of glycolate and propanediol
EJN92_RS20450	COG1047	Peptidyl-prolyl cis-trans
EJN92_RS20460	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
EJN92_RS20480	COG0477	Major facilitator Superfamily
EJN92_RS20500	COG1639	'signal transduction protein
EJN92_RS20530	COG0456	acetyltransferase
EJN92_RS20555	COG4654	Cytochrome c, class I
EJN92_RS20575	COG3154	lipid carrier protein
EJN92_RS20585	COG0826	peptidase U32
EJN92_RS20590	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EJN92_RS20595	COG2197	response regulator
EJN92_RS20600	COG3850	Histidine kinase
EJN92_RS20605	COG0288	reversible hydration of carbon dioxide
EJN92_RS20610	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EJN92_RS20625	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EJN92_RS20630	COG2181	nitrate reductase activity
EJN92_RS20635	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EJN92_RS20640	COG1140	nitrate reductase beta subunit
EJN92_RS20645	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EJN92_RS20650	COG2223	nitrite transmembrane transporter activity
EJN92_RS20665	COG3158	transport of potassium into the cell
EJN92_RS20675	COG0527	aspartate kinase activity
EJN92_RS20685	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EJN92_RS20690	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EJN92_RS20695	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EJN92_RS20700	COG3012	SEC-C Motif Domain Protein
EJN92_RS20700	COG3318	Belongs to the UPF0149 family
EJN92_RS20710	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EJN92_RS20720	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EJN92_RS20725	COG0492	ferredoxin-NADP+ reductase activity
EJN92_RS20740	COG2878	Part of a membrane complex involved in electron transport
EJN92_RS20745	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EJN92_RS20750	COG0778	Nitroreductase
EJN92_RS20770	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EJN92_RS20775	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EJN92_RS20780	COG0440	acetolactate synthase activity
EJN92_RS20785	COG0028	Belongs to the TPP enzyme family
EJN92_RS20810	COG1309	transcriptional regulator
EJN92_RS20825	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EJN92_RS20830	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EJN92_RS20835	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EJN92_RS20840	COG3228	Belongs to the MtfA family
EJN92_RS20845	COG2962	Rard protein
EJN92_RS20865	COG3172	ATPase kinase involved in NAD metabolism
EJN92_RS20880	COG1492	cobalamin metabolic process
EJN92_RS20890	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EJN92_RS20910	COG1797	cobyrinic acid a,c-diamide synthase activity
EJN92_RS20920	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
EJN92_RS20925	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EJN92_RS20930	COG4771	TonB-dependent receptor
EJN92_RS20945	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
EJN92_RS20950	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
EJN92_RS20960	COG3275	phosphorelay sensor kinase activity
EJN92_RS20965	COG0165	Argininosuccinate lyase
EJN92_RS20975	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EJN92_RS20980	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
EJN92_RS20985	COG0312	modulator of DNA gyrase
EJN92_RS20995	COG0521	Mo-molybdopterin cofactor biosynthetic process
EJN92_RS21000	COG0400	carboxylic ester hydrolase activity
EJN92_RS21005	COG0626	cystathionine gamma-synthase activity
EJN92_RS21010	COG2010	Cytochrome c
EJN92_RS21030	COG0714	Associated with various cellular activities
EJN92_RS21065	COG1414	Transcriptional regulator
EJN92_RS21070	COG0681	Belongs to the peptidase S26 family
EJN92_RS21075	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EJN92_RS21080	COG0456	acetyltransferase
EJN92_RS21095	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EJN92_RS21120	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EJN92_RS21160	COG0583	DNA-binding transcription factor activity
EJN92_RS21170	COG0196	riboflavin kinase activity
EJN92_RS21175	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EJN92_RS21180	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EJN92_RS21190	COG0756	dUTP diphosphatase activity
EJN92_RS21195	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
EJN92_RS21200	COG0501	Belongs to the peptidase M48B family
EJN92_RS21205	COG2154	pterin-4-alpha-carbinolamine dehydratase
EJN92_RS21210	COG1162	GTPase activity
EJN92_RS21220	COG0583	DNA-binding transcription factor activity
EJN92_RS21225	COG5002	protein histidine kinase activity
EJN92_RS21235	COG3340	Belongs to the peptidase S51 family
EJN92_RS21255	COG1136	(ABC) transporter
EJN92_RS21270	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EJN92_RS21275	COG3590	peptidase
EJN92_RS21290	COG1620	l-lactate permease
EJN92_RS21295	COG0288	reversible hydration of carbon dioxide
EJN92_RS21300	COG0501	Belongs to the peptidase M48B family
EJN92_RS21305	COG3047	cAMP biosynthetic process
EJN92_RS21310	COG5002	protein histidine kinase activity
EJN92_RS21315	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EJN92_RS21335	COG1028	Short-chain dehydrogenase reductase Sdr