locus-tag	class	description
UNDKW_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
UNDKW_RS00040	COG0740	serine-type endopeptidase activity
UNDKW_RS00045	COG1473	amidohydrolase
UNDKW_RS00055	COG0601	transmembrane transport
UNDKW_RS00060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
UNDKW_RS00065	COG0444	Belongs to the ABC transporter superfamily
UNDKW_RS00070	COG4608	Belongs to the ABC transporter superfamily
UNDKW_RS00085	COG3739	integral membrane protein
UNDKW_RS00125	COG1595	DNA-templated transcription, initiation
UNDKW_RS00130	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
UNDKW_RS00185	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
UNDKW_RS00200	COG2204	response regulator
UNDKW_RS00205	COG5000	phosphorelay sensor kinase activity
UNDKW_RS00255	COG2205	protein histidine kinase activity
UNDKW_RS00345	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
UNDKW_RS00360	COG0606	chelatase, subunit chli
UNDKW_RS00375	COG0347	Belongs to the P(II) protein family
UNDKW_RS00380	COG0004	ammonium transporteR
UNDKW_RS00400	COG5001	Diguanylate cyclase
UNDKW_RS00400	COG5002	protein histidine kinase activity
UNDKW_RS00410	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
UNDKW_RS00445	COG0515	serine threonine protein kinase
UNDKW_RS00445	COG2815	serine threonine protein kinase
UNDKW_RS00455	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
UNDKW_RS00465	COG0813	purine-nucleoside phosphorylase activity
UNDKW_RS00475	COG0488	(ABC) transporter
UNDKW_RS00480	COG3047	cAMP biosynthetic process
UNDKW_RS00490	COG1136	(ABC) transporter
UNDKW_RS00495	COG0577	efflux transmembrane transporter activity
UNDKW_RS00495	COG1136	(ABC) transporter
UNDKW_RS00500	COG0577	efflux transmembrane transporter activity
UNDKW_RS00500	COG1136	(ABC) transporter
UNDKW_RS00505	COG2204	response regulator
UNDKW_RS00510	COG5000	phosphorelay sensor kinase activity
UNDKW_RS00535	COG0631	protein serine/threonine phosphatase activity
UNDKW_RS00540	COG0515	serine threonine protein kinase
UNDKW_RS00555	COG4206	TonB-dependent receptor
UNDKW_RS00560	COG3291	Pkd domain containing protein
UNDKW_RS00595	COG5001	Diguanylate cyclase
UNDKW_RS00595	COG3300	MHYT domain
UNDKW_RS00610	COG3706	GGDEF domain
UNDKW_RS00620	COG1522	sequence-specific DNA binding
UNDKW_RS00635	COG3279	Response regulator of the LytR AlgR family
UNDKW_RS00650	COG0583	DNA-binding transcription factor activity
UNDKW_RS00655	COG1653	transport
UNDKW_RS00670	COG3842	ATPase activity
UNDKW_RS00680	COG2723	6-phospho-beta-galactosidase activity
UNDKW_RS00685	COG4771	TonB-dependent receptor
UNDKW_RS00695	COG1472	Belongs to the glycosyl hydrolase 3 family
UNDKW_RS00700	COG1737	Transcriptional regulator
UNDKW_RS00700	COG0837	glucose binding
UNDKW_RS00720	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
UNDKW_RS00720	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
UNDKW_RS00720	COG1703	isobutyryl-CoA mutase activity
UNDKW_RS00735	COG2814	Major facilitator Superfamily
UNDKW_RS00750	COG1609	Transcriptional regulator
UNDKW_RS00795	COG2205	protein histidine kinase activity
UNDKW_RS00795	COG0784	Response regulator, receiver
UNDKW_RS00800	COG2824	Alkylphosphonate utilization operon protein PhnA
UNDKW_RS00820	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
UNDKW_RS00825	COG1477	protein flavinylation
UNDKW_RS00845	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
UNDKW_RS00890	COG1522	sequence-specific DNA binding
UNDKW_RS00910	COG0732	type I restriction modification DNA specificity domain
UNDKW_RS00965	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
UNDKW_RS00980	COG2192	nodulation
UNDKW_RS01000	COG3335	DDE superfamily endonuclease
UNDKW_RS01025	COG1944	ATP diphosphatase activity
UNDKW_RS01050	COG2197	response regulator
UNDKW_RS01055	COG4585	Histidine kinase
UNDKW_RS01065	COG3706	GGDEF domain
UNDKW_RS01070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
UNDKW_RS01115	COG0583	DNA-binding transcription factor activity
UNDKW_RS01150	COG5002	protein histidine kinase activity
UNDKW_RS01160	COG1045	serine acetyltransferase
UNDKW_RS01165	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
UNDKW_RS01170	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
UNDKW_RS01175	COG1309	transcriptional regulator
UNDKW_RS01185	COG2267	carboxylic ester hydrolase activity
UNDKW_RS01220	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
UNDKW_RS01235	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
UNDKW_RS01240	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
UNDKW_RS01240	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
UNDKW_RS01250	COG1051	belongs to the nudix hydrolase family
UNDKW_RS01250	COG1056	cytidyltransferase-related domain
UNDKW_RS01260	COG0642	Histidine kinase
UNDKW_RS01265	COG0745	RESPONSE REGULATOR receiver
UNDKW_RS01270	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
UNDKW_RS01275	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
UNDKW_RS01280	COG2721	sulfolactate sulfo-lyase activity
UNDKW_RS01285	COG2186	Transcriptional regulator
UNDKW_RS01290	COG4206	TonB-dependent receptor
UNDKW_RS01315	COG2271	Major facilitator Superfamily
UNDKW_RS01330	COG2186	Transcriptional regulator
UNDKW_RS01355	COG0484	heat shock protein binding
UNDKW_RS01365	COG0004	ammonium transporteR
UNDKW_RS01380	COG2070	2-Nitropropane dioxygenase
UNDKW_RS01385	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
UNDKW_RS01395	COG1522	sequence-specific DNA binding
UNDKW_RS01405	COG0789	Transcriptional regulator
UNDKW_RS01415	COG0745	RESPONSE REGULATOR receiver
UNDKW_RS01420	COG2205	protein histidine kinase activity
UNDKW_RS01430	COG1435	thymidine kinase activity
UNDKW_RS01455	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
UNDKW_RS01475	COG0583	DNA-binding transcription factor activity
UNDKW_RS01495	COG0411	ABC transporter
UNDKW_RS01515	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
UNDKW_RS01530	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
UNDKW_RS01545	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
UNDKW_RS01550	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
UNDKW_RS01555	COG3639	organic phosphonate transmembrane transporter activity
UNDKW_RS01565	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
UNDKW_RS01570	COG3454	Phosphonate metabolism
UNDKW_RS01575	COG3624	Phosphonate C-P lyase system protein PhnG
UNDKW_RS01580	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
UNDKW_RS01585	COG3626	phosphonate metabolism
UNDKW_RS01590	COG3627	carbon phosphorus lyase activity
UNDKW_RS01595	COG4107	phosphonate C-P lyase system protein PhnK
UNDKW_RS01600	COG4778	phosphonate C-P lyase system protein PhnL
UNDKW_RS01605	COG3454	Phosphonate metabolism
UNDKW_RS01610	COG0037	tRNA processing
UNDKW_RS01620	COG1028	Short-chain dehydrogenase reductase Sdr
UNDKW_RS01635	COG0745	RESPONSE REGULATOR receiver
UNDKW_RS01645	COG1280	lysine exporter protein (LysE YggA)
UNDKW_RS01655	COG1393	Belongs to the ArsC family
UNDKW_RS01660	COG2119	membrane
UNDKW_RS01670	COG1309	transcriptional regulator
UNDKW_RS01690	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
UNDKW_RS01710	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
UNDKW_RS01715	COG0081	regulation of translation
UNDKW_RS01720	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
UNDKW_RS01725	COG0222	ribosome binding
UNDKW_RS01730	COG0085	RNA polymerase activity
UNDKW_RS01735	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
UNDKW_RS01740	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
UNDKW_RS01740	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
UNDKW_RS01745	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
UNDKW_RS01775	COG0402	S-adenosylhomocysteine deaminase activity
UNDKW_RS01805	COG0019	diaminopimelate decarboxylase activity
UNDKW_RS01810	COG1522	sequence-specific DNA binding
UNDKW_RS01820	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
UNDKW_RS01825	COG0431	NADPH-dependent FMN reductase
UNDKW_RS01830	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
UNDKW_RS01835	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
UNDKW_RS01940	COG0205	6-phosphofructokinase activity
UNDKW_RS01965	COG0640	Transcriptional regulator
UNDKW_RS02000	COG1802	Transcriptional regulator
UNDKW_RS02005	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
UNDKW_RS02025	COG3052	prosthetic group binding
UNDKW_RS02060	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
UNDKW_RS02075	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
UNDKW_RS02110	COG1475	DNA binding
UNDKW_RS02170	COG3620	sequence-specific DNA binding
UNDKW_RS02185	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
UNDKW_RS02200	COG1335	isochorismatase
UNDKW_RS02210	COG0583	DNA-binding transcription factor activity
UNDKW_RS02215	COG2921	Belongs to the UPF0250 family
UNDKW_RS02220	COG0583	DNA-binding transcription factor activity
UNDKW_RS02235	COG1686	Belongs to the peptidase S11 family
UNDKW_RS02240	COG2945	thiolester hydrolase activity
UNDKW_RS02265	COG1127	ABC transporter
UNDKW_RS02270	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
UNDKW_RS02275	COG2194	sulfuric ester hydrolase activity
UNDKW_RS02280	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
UNDKW_RS02285	COG0049	tRNA binding
UNDKW_RS02290	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
UNDKW_RS02295	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
UNDKW_RS02300	COG0051	transcription antitermination factor activity, RNA binding
UNDKW_RS02305	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
UNDKW_RS02310	COG0088	Forms part of the polypeptide exit tunnel
UNDKW_RS02315	COG0089	rRNA binding
UNDKW_RS02320	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
UNDKW_RS02325	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
UNDKW_RS02330	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
UNDKW_RS02335	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
UNDKW_RS02340	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
UNDKW_RS02345	COG0255	Belongs to the universal ribosomal protein uL29 family
UNDKW_RS02355	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
UNDKW_RS02360	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
UNDKW_RS02365	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
UNDKW_RS02370	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
UNDKW_RS02375	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
UNDKW_RS02380	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
UNDKW_RS02385	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
UNDKW_RS02390	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
UNDKW_RS02395	COG1841	ribosomal large subunit assembly
UNDKW_RS02400	COG0200	Binds to the 23S rRNA
UNDKW_RS02405	COG0201	protein transport
UNDKW_RS02410	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
UNDKW_RS02415	COG0257	Belongs to the bacterial ribosomal protein bL36 family
UNDKW_RS02420	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
UNDKW_RS02425	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
UNDKW_RS02430	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
UNDKW_RS02435	COG0202	RNA polymerase activity
UNDKW_RS02440	COG0203	ribosomal protein L17
UNDKW_RS02450	COG4232	protein-disulfide reductase activity
UNDKW_RS02455	COG0450	alkyl hydroperoxide reductase
UNDKW_RS02460	COG2925	Exonuclease
UNDKW_RS02465	COG0598	Magnesium transport protein CorA
UNDKW_RS02485	COG0218	Necessary for normal cell division and for the maintenance of normal septation
UNDKW_RS02495	COG1333	cytochrome c biogenesis protein
UNDKW_RS02500	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
UNDKW_RS02505	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
UNDKW_RS02510	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
UNDKW_RS02525	COG1965	Belongs to the frataxin family
UNDKW_RS02570	COG0232	Belongs to the dGTPase family. Type 2 subfamily
UNDKW_RS02605	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
UNDKW_RS02610	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
UNDKW_RS02615	COG1137	ATPase activity
UNDKW_RS02630	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
UNDKW_RS02635	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
UNDKW_RS02635	COG0517	IMP dehydrogenase activity
UNDKW_RS02645	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
UNDKW_RS02655	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
UNDKW_RS02660	COG1950	PFAM Membrane protein of
UNDKW_RS02685	COG1522	sequence-specific DNA binding
UNDKW_RS02690	COG0626	cystathionine gamma-synthase activity
UNDKW_RS02710	COG1132	(ABC) transporter
UNDKW_RS02715	COG1132	(ABC) transporter
UNDKW_RS02720	COG2770	Histidine kinase
UNDKW_RS02720	COG2208	phosphoserine phosphatase activity
UNDKW_RS02740	COG1505	serine-type exopeptidase activity
UNDKW_RS02745	COG2205	protein histidine kinase activity
UNDKW_RS02810	COG1335	isochorismatase
UNDKW_RS02820	COG4452	Inner membrane protein CreD
UNDKW_RS02825	COG2205	protein histidine kinase activity
UNDKW_RS02830	COG0745	RESPONSE REGULATOR receiver
UNDKW_RS02835	COG0295	cytidine deaminase activity
UNDKW_RS02885	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
UNDKW_RS02920	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
UNDKW_RS02925	COG2313	pseudouridylate synthase activity
UNDKW_RS02965	COG1943	Transposase
UNDKW_RS02985	COG5507	3-demethylubiquinone-9 3-methyltransferase
UNDKW_RS02995	COG0583	DNA-binding transcription factor activity
UNDKW_RS03015	COG0583	DNA-binding transcription factor activity
UNDKW_RS03030	COG0583	DNA-binding transcription factor activity
UNDKW_RS03040	COG2129	metallophosphoesterase
UNDKW_RS03090	COG2319	Wd-40 repeat
UNDKW_RS03105	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
UNDKW_RS03110	COG2137	regulation of response to DNA damage stimulus
UNDKW_RS03120	COG0045	succinate-CoA ligase (ADP-forming) activity
UNDKW_RS03125	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
UNDKW_RS03140	COG4969	Belongs to the N-Me-Phe pilin family
UNDKW_RS03155	COG0405	Gamma-glutamyltransferase
UNDKW_RS03160	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
UNDKW_RS03165	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
UNDKW_RS03175	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
UNDKW_RS03180	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
UNDKW_RS03190	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
UNDKW_RS03210	COG4555	ABC transporter
UNDKW_RS03215	COG1668	transmembrane transport
UNDKW_RS03225	COG0519	Catalyzes the synthesis of GMP from XMP
UNDKW_RS03250	COG2308	Evidence 4 Homologs of previously reported genes of
UNDKW_RS03270	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
UNDKW_RS03290	COG0617	tRNA 3'-terminal CCA addition
UNDKW_RS03300	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
UNDKW_RS03305	COG0628	permease
UNDKW_RS03350	COG1660	Displays ATPase and GTPase activities
UNDKW_RS03355	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
UNDKW_RS03365	COG5001	Diguanylate cyclase
UNDKW_RS03365	COG3300	MHYT domain
UNDKW_RS03375	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
UNDKW_RS03375	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
UNDKW_RS03380	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
UNDKW_RS03385	COG1238	metal cluster binding
UNDKW_RS03430	COG2130	NADP-dependent
UNDKW_RS03435	COG0583	DNA-binding transcription factor activity
UNDKW_RS03440	COG2226	methyltransferase
UNDKW_RS03455	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
UNDKW_RS03470	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
UNDKW_RS03510	COG2972	Histidine kinase
UNDKW_RS03560	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
UNDKW_RS03565	COG1522	sequence-specific DNA binding
UNDKW_RS03605	COG0420	3'-5' exonuclease activity
UNDKW_RS03625	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
UNDKW_RS03640	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
UNDKW_RS03655	COG0494	nUDIX hydrolase
UNDKW_RS03660	COG3568	Endonuclease Exonuclease Phosphatase
UNDKW_RS03665	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
UNDKW_RS03710	COG1960	acyl-CoA dehydrogenase activity
UNDKW_RS03715	COG1250	3-hydroxyacyl-CoA dehydrogenase
UNDKW_RS03715	COG1024	Enoyl-CoA hydratase
UNDKW_RS03720	COG0183	Belongs to the thiolase family
UNDKW_RS03730	COG1024	Enoyl-CoA hydratase
UNDKW_RS03755	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
UNDKW_RS03760	COG0318	PFAM AMP-dependent synthetase and ligase
UNDKW_RS03780	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
UNDKW_RS03785	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
UNDKW_RS03790	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
UNDKW_RS03800	COG4716	Myosin-crossreactive antigen
UNDKW_RS03830	COG2823	Periplasmic or secreted lipoprotein
UNDKW_RS03840	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
UNDKW_RS03845	COG1063	alcohol dehydrogenase
UNDKW_RS03910	COG4650	regulator
UNDKW_RS03925	COG1690	Belongs to the RtcB family
UNDKW_RS03930	COG0430	RNA-3'-phosphate cyclase activity
UNDKW_RS03975	COG2001	Belongs to the MraZ family
UNDKW_RS03980	COG0275	rRNA processing
UNDKW_RS03995	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
UNDKW_RS04000	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
UNDKW_RS04005	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
UNDKW_RS04020	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
UNDKW_RS04025	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
UNDKW_RS04030	COG1181	Belongs to the D-alanine--D-alanine ligase family
UNDKW_RS04035	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
UNDKW_RS04045	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
UNDKW_RS04050	COG0678	peroxiredoxin activity
UNDKW_RS04060	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
UNDKW_RS04070	COG1196	nuclear chromosome segregation
UNDKW_RS04070	COG0741	lytic transglycosylase activity
UNDKW_RS04070	COG0739	heme binding
UNDKW_RS04075	COG0653	protein targeting
UNDKW_RS04080	COG1960	acyl-CoA dehydrogenase activity
UNDKW_RS04085	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
UNDKW_RS04100	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
UNDKW_RS04105	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
UNDKW_RS04120	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
UNDKW_RS04125	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
UNDKW_RS04150	COG0142	geranyltranstransferase activity
UNDKW_RS04155	COG0261	This protein binds to 23S rRNA in the presence of protein L20
UNDKW_RS04160	COG0211	Belongs to the bacterial ribosomal protein bL27 family
UNDKW_RS04165	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
UNDKW_RS04170	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
UNDKW_RS04185	COG0442	prolyl-tRNA aminoacylation
UNDKW_RS04190	COG0741	lytic transglycosylase activity
UNDKW_RS04215	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
UNDKW_RS04225	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
UNDKW_RS04230	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
UNDKW_RS04235	COG1116	anion transmembrane transporter activity
UNDKW_RS04245	COG4191	Histidine kinase
UNDKW_RS04250	COG2204	response regulator
UNDKW_RS04290	COG0762	integral membrane protein
UNDKW_RS04295	COG1609	Transcriptional regulator
UNDKW_RS04300	COG0402	S-adenosylhomocysteine deaminase activity
UNDKW_RS04305	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
UNDKW_RS04310	COG0351	phosphomethylpyrimidine kinase
UNDKW_RS04315	COG1773	rubredoxin
UNDKW_RS04335	COG0840	transmembrane signaling receptor activity
UNDKW_RS04340	COG2198	Histidine kinase
UNDKW_RS04340	COG0643	Histidine kinase
UNDKW_RS04340	COG2198	Histidine kinase
UNDKW_RS04340	COG0643	Histidine kinase
UNDKW_RS04345	COG0415	Belongs to the DNA photolyase family
UNDKW_RS04350	COG1678	Uncharacterized ACR, COG1678
UNDKW_RS04355	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
UNDKW_RS04360	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
UNDKW_RS04365	COG0540	Belongs to the ATCase OTCase family
UNDKW_RS04380	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
UNDKW_RS04385	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
UNDKW_RS04390	COG0497	DNA recombination
UNDKW_RS04405	COG1420	regulation of RNA biosynthetic process
UNDKW_RS04415	COG0735	belongs to the Fur family
UNDKW_RS04420	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
UNDKW_RS04425	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
UNDKW_RS04440	COG0495	leucyl-tRNA aminoacylation
UNDKW_RS04455	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
UNDKW_RS04475	COG2814	Major facilitator Superfamily
UNDKW_RS04480	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
UNDKW_RS04490	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
UNDKW_RS04500	COG1765	OsmC-like protein
UNDKW_RS04505	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
UNDKW_RS04510	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
UNDKW_RS04515	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
UNDKW_RS04530	COG0316	Belongs to the HesB IscA family
UNDKW_RS04540	COG0277	FAD linked oxidase domain protein
UNDKW_RS04545	COG0277	FAD linked oxidase domain protein
UNDKW_RS04550	COG0247	lactate metabolic process
UNDKW_RS04570	COG0386	Belongs to the glutathione peroxidase family
UNDKW_RS04610	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
UNDKW_RS04620	COG1175	transmembrane transport
UNDKW_RS04625	COG0395	ABC-type sugar transport system, permease component
UNDKW_RS04645	COG1752	Esterase of the alpha-beta hydrolase superfamily
UNDKW_RS04650	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
UNDKW_RS04655	COG0583	DNA-binding transcription factor activity
UNDKW_RS04665	COG1846	Transcriptional regulator
UNDKW_RS04665	COG0456	acetyltransferase
UNDKW_RS04675	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
UNDKW_RS04680	COG0343	queuine tRNA-ribosyltransferase activity
UNDKW_RS04695	COG1862	Preprotein translocase
UNDKW_RS04700	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
UNDKW_RS04705	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
UNDKW_RS04710	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
UNDKW_RS04720	COG1846	Transcriptional regulator
UNDKW_RS04725	COG2353	YceI-like domain
UNDKW_RS04735	COG3038	cytochrome b561
UNDKW_RS04750	COG0625	glutathione transferase activity
UNDKW_RS04810	COG0688	phosphatidylethanolamine metabolic process
UNDKW_RS04825	COG0450	alkyl hydroperoxide reductase
UNDKW_RS04830	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
UNDKW_RS04845	COG1446	asparaginase
UNDKW_RS04855	COG0482	sulfurtransferase activity
UNDKW_RS04870	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
UNDKW_RS04910	COG0789	Transcriptional regulator
UNDKW_RS04920	COG2423	ornithine cyclodeaminase activity
UNDKW_RS04925	COG1522	sequence-specific DNA binding
UNDKW_RS04930	COG0745	RESPONSE REGULATOR receiver
UNDKW_RS04935	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
UNDKW_RS04935	COG2199	diguanylate cyclase activity
UNDKW_RS04940	COG1280	lysine exporter protein (LysE YggA)
UNDKW_RS04955	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
UNDKW_RS04970	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
UNDKW_RS04975	COG1845	cytochrome c oxidase, subunit III
UNDKW_RS04980	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
UNDKW_RS04990	COG0477	Major facilitator Superfamily
UNDKW_RS04995	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
UNDKW_RS05000	COG0006	proline dipeptidase activity
UNDKW_RS05005	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
UNDKW_RS05015	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
UNDKW_RS05020	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
UNDKW_RS05025	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
UNDKW_RS05030	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
UNDKW_RS05035	COG2201	protein-glutamate methylesterase activity
UNDKW_RS05040	COG0166	Belongs to the GPI family
UNDKW_RS05060	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
UNDKW_RS05070	COG3135	benzoate transporter
UNDKW_RS05075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
UNDKW_RS05130	COG0644	oxidoreductase
UNDKW_RS05135	COG0626	cystathionine gamma-synthase activity
UNDKW_RS05150	COG2723	6-phospho-beta-galactosidase activity
UNDKW_RS05165	COG4771	TonB-dependent receptor
UNDKW_RS05175	COG1609	Transcriptional regulator
UNDKW_RS05180	COG1309	transcriptional regulator
UNDKW_RS05195	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
UNDKW_RS05205	COG1538	Outer membrane efflux protein
UNDKW_RS05220	COG1136	(ABC) transporter
UNDKW_RS05270	COG0366	Alpha amylase catalytic
UNDKW_RS05280	COG1737	Transcriptional regulator
UNDKW_RS05280	COG0837	glucose binding
UNDKW_RS05310	COG0583	DNA-binding transcription factor activity
UNDKW_RS05320	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
UNDKW_RS05325	COG0346	lactoylglutathione lyase activity
UNDKW_RS05360	COG0366	Alpha amylase catalytic
UNDKW_RS05385	COG0640	Transcriptional regulator
UNDKW_RS05395	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
UNDKW_RS05420	COG2823	Periplasmic or secreted lipoprotein
UNDKW_RS05430	COG0628	permease
UNDKW_RS05455	COG2197	response regulator
UNDKW_RS05495	COG1704	LemA family
UNDKW_RS05510	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
UNDKW_RS05535	COG0443	Heat shock 70 kDa protein
UNDKW_RS05555	COG2814	Major facilitator Superfamily
UNDKW_RS05560	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
UNDKW_RS05565	COG0586	Pfam SNARE associated Golgi protein
UNDKW_RS05580	COG1280	lysine exporter protein (LysE YggA)
UNDKW_RS05595	COG0860	N-Acetylmuramoyl-L-alanine amidase
UNDKW_RS05600	COG0802	atpase or kinase
UNDKW_RS05605	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
UNDKW_RS05620	COG4566	intracellular signal transduction
UNDKW_RS05650	COG4974	Belongs to the 'phage' integrase family
UNDKW_RS05660	COG4771	TonB-dependent receptor
UNDKW_RS05690	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
UNDKW_RS05700	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
UNDKW_RS05710	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
UNDKW_RS05715	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
UNDKW_RS05720	COG1116	anion transmembrane transporter activity
UNDKW_RS05730	COG2766	serine protein kinase
UNDKW_RS05735	COG2718	Belongs to the UPF0229 family
UNDKW_RS05740	COG2719	SpoVR family
UNDKW_RS05760	COG0454	-acetyltransferase
UNDKW_RS05760	COG0456	acetyltransferase
UNDKW_RS05780	COG0531	amino acid
UNDKW_RS05785	COG3045	CreA protein
UNDKW_RS05810	COG1131	(ABC) transporter
UNDKW_RS05815	COG0842	Transport permease protein
UNDKW_RS05825	COG3023	N-Acetylmuramoyl-L-alanine amidase
UNDKW_RS05860	COG0583	DNA-binding transcription factor activity
UNDKW_RS05865	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
UNDKW_RS05885	COG1649	PFAM Uncharacterised BCR, COG1649
UNDKW_RS05930	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
UNDKW_RS05935	COG0751	glycine-tRNA ligase activity
UNDKW_RS05975	COG1506	peptidase
UNDKW_RS05975	COG0823	Involved in the tonB-independent uptake of proteins
UNDKW_RS05975	COG4946	Tricorn protease homolog
UNDKW_RS06050	COG5001	Diguanylate cyclase
UNDKW_RS06060	COG2318	DinB family
UNDKW_RS06075	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
UNDKW_RS06085	COG3104	oligopeptide transport
UNDKW_RS06110	COG0598	Magnesium transport protein CorA
UNDKW_RS06115	COG2207	Transcriptional regulator
UNDKW_RS06140	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
UNDKW_RS06160	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
UNDKW_RS06185	COG0259	pyridoxamine-phosphate oxidase activity
UNDKW_RS06190	COG3945	hemerythrin HHE cation binding domain
UNDKW_RS06195	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
UNDKW_RS06210	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
UNDKW_RS06235	COG2217	Heavy metal translocating P-type atpase
UNDKW_RS06245	COG3437	response regulator, receiver
UNDKW_RS06245	COG0784	Response regulator, receiver
UNDKW_RS06250	COG1309	transcriptional regulator
UNDKW_RS06255	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
UNDKW_RS06270	COG0493	'glutamate synthase
UNDKW_RS06280	COG1953	Uracil, thiamine, allantoin
UNDKW_RS06330	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
UNDKW_RS06335	COG2249	NAD(P)H dehydrogenase (quinone) activity
UNDKW_RS06340	COG0789	Transcriptional regulator
UNDKW_RS06355	COG2815	serine threonine protein kinase
UNDKW_RS06355	COG0515	serine threonine protein kinase
UNDKW_RS06360	COG2223	nitrite transmembrane transporter activity
UNDKW_RS06365	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
UNDKW_RS06370	COG2146	nitrite reductase [NAD(P)H] activity
UNDKW_RS06375	COG0243	molybdopterin cofactor binding
UNDKW_RS06430	COG3590	peptidase
UNDKW_RS06460	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
UNDKW_RS06465	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
UNDKW_RS06470	COG0583	DNA-binding transcription factor activity
UNDKW_RS06480	COG4654	Cytochrome c, class I
UNDKW_RS06490	COG1522	sequence-specific DNA binding
UNDKW_RS06495	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
UNDKW_RS06520	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
UNDKW_RS06530	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
UNDKW_RS06535	COG0508	dehydrogenase complex catalyzes the overall conversion of
UNDKW_RS06540	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
UNDKW_RS06545	COG0612	Peptidase, M16
UNDKW_RS06565	COG3706	GGDEF domain
UNDKW_RS06590	COG1136	(ABC) transporter
UNDKW_RS06645	COG2130	NADP-dependent
UNDKW_RS06650	COG0583	DNA-binding transcription factor activity
UNDKW_RS06660	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
UNDKW_RS06665	COG0543	2 iron, 2 sulfur cluster binding
UNDKW_RS06665	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
UNDKW_RS06680	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
UNDKW_RS06685	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
UNDKW_RS06735	COG3706	GGDEF domain
UNDKW_RS06745	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
UNDKW_RS06755	COG0697	spore germination
UNDKW_RS06765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
UNDKW_RS06785	COG1187	pseudouridine synthase activity
UNDKW_RS06790	COG1192	Involved in chromosome partitioning
UNDKW_RS06800	COG3594	Acyltransferase
UNDKW_RS06815	COG2205	protein histidine kinase activity
UNDKW_RS06820	COG0745	RESPONSE REGULATOR receiver
UNDKW_RS06825	COG1546	Belongs to the CinA family
UNDKW_RS06835	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
UNDKW_RS06905	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
UNDKW_RS06910	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
UNDKW_RS06915	COG4221	oxidoreductase activity
UNDKW_RS06920	COG0824	Thioesterase
UNDKW_RS06935	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
UNDKW_RS06945	COG0612	Peptidase, M16
UNDKW_RS06970	COG1309	transcriptional regulator
UNDKW_RS06990	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
UNDKW_RS07005	COG1715	Restriction endonuclease
UNDKW_RS07015	COG0534	Mate efflux family protein
UNDKW_RS07025	COG0254	rRNA binding
UNDKW_RS07030	COG2860	membrane
UNDKW_RS07050	COG1538	Outer membrane efflux protein
UNDKW_RS07075	COG1959	2 iron, 2 sulfur cluster binding
UNDKW_RS07095	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
UNDKW_RS07110	COG1074	ATP-dependent DNA helicase activity
UNDKW_RS07135	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
UNDKW_RS07150	COG0596	Alpha beta hydrolase
UNDKW_RS07160	COG4771	TonB-dependent receptor
UNDKW_RS07170	COG5001	Diguanylate cyclase
UNDKW_RS07170	COG3300	MHYT domain
UNDKW_RS07180	COG0840	transmembrane signaling receptor activity
UNDKW_RS07205	COG1309	transcriptional regulator
UNDKW_RS07210	COG2081	HI0933 family
UNDKW_RS07215	COG0828	Belongs to the bacterial ribosomal protein bS21 family
UNDKW_RS07240	COG0513	Belongs to the DEAD box helicase family
UNDKW_RS07245	COG2423	ornithine cyclodeaminase activity
UNDKW_RS07255	COG0583	DNA-binding transcription factor activity
UNDKW_RS07265	COG1028	Short-chain dehydrogenase reductase Sdr
UNDKW_RS07275	COG1960	acyl-CoA dehydrogenase activity
UNDKW_RS07280	COG0318	PFAM AMP-dependent synthetase and ligase
UNDKW_RS07290	COG1090	epimerase
UNDKW_RS07305	COG0745	RESPONSE REGULATOR receiver
UNDKW_RS07310	COG0642	Histidine kinase
UNDKW_RS07330	COG1733	regulation of RNA biosynthetic process
UNDKW_RS07340	COG0702	epimerase
UNDKW_RS07350	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
UNDKW_RS07365	COG2197	response regulator
UNDKW_RS07370	COG4585	Histidine kinase
UNDKW_RS07375	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
UNDKW_RS07380	COG0616	signal peptide processing
UNDKW_RS07395	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
UNDKW_RS07410	COG0765	amino acid transport
UNDKW_RS07460	COG2971	BadF BadG BcrA BcrD
UNDKW_RS07465	COG2188	Transcriptional regulator
UNDKW_RS07475	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
UNDKW_RS07485	COG1175	transmembrane transport
UNDKW_RS07490	COG0395	ABC-type sugar transport system, permease component
UNDKW_RS07500	COG3842	ATPase activity
UNDKW_RS07515	COG0583	DNA-binding transcription factor activity
UNDKW_RS07520	COG0604	alcohol dehydrogenase
UNDKW_RS07540	COG3279	Response regulator of the LytR AlgR family
UNDKW_RS07545	COG3275	phosphorelay sensor kinase activity
UNDKW_RS07585	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
UNDKW_RS07595	COG3706	GGDEF domain
UNDKW_RS07610	COG0823	Involved in the tonB-independent uptake of proteins
UNDKW_RS07610	COG1506	peptidase
UNDKW_RS07620	COG1794	racemase activity, acting on amino acids and derivatives
UNDKW_RS07630	COG1725	Transcriptional regulator
UNDKW_RS07635	COG1131	(ABC) transporter
UNDKW_RS07650	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
UNDKW_RS07655	COG1570	exodeoxyribonuclease VII activity
UNDKW_RS07660	COG0811	peptide transport
UNDKW_RS07665	COG0848	biopolymer transport protein
UNDKW_RS07670	COG1663	tetraacyldisaccharide 4'-kinase activity
UNDKW_RS07675	COG2835	tetraacyldisaccharide 4'-kinase activity
UNDKW_RS07680	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
UNDKW_RS07685	COG0563	adenylate kinase activity
UNDKW_RS07715	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
UNDKW_RS07720	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
UNDKW_RS07720	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
UNDKW_RS07725	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
UNDKW_RS07725	COG3264	Mechanosensitive ion channel
UNDKW_RS07735	COG0745	RESPONSE REGULATOR receiver
UNDKW_RS07745	COG0784	Response regulator, receiver
UNDKW_RS07745	COG2205	protein histidine kinase activity
UNDKW_RS07745	COG5002	protein histidine kinase activity
UNDKW_RS07750	COG0267	Belongs to the bacterial ribosomal protein bL33 family
UNDKW_RS07755	COG0227	Belongs to the bacterial ribosomal protein bL28 family
UNDKW_RS07760	COG2003	Belongs to the UPF0758 family
UNDKW_RS07770	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
UNDKW_RS07775	COG0559	Belongs to the binding-protein-dependent transport system permease family
UNDKW_RS07800	COG2223	nitrite transmembrane transporter activity
UNDKW_RS07840	COG5492	domain, Protein
UNDKW_RS07840	COG4932	domain protein
UNDKW_RS07855	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
UNDKW_RS07865	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
UNDKW_RS07870	COG0312	modulator of DNA gyrase
UNDKW_RS07875	COG2894	cell division
UNDKW_RS07890	COG0489	protein tyrosine kinase activity
UNDKW_RS07900	COG0457	Tetratricopeptide repeat
UNDKW_RS07905	COG0457	Tetratricopeptide repeat
UNDKW_RS07915	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
UNDKW_RS07930	COG1666	GTP binding
UNDKW_RS07945	COG0501	Belongs to the peptidase M48B family
UNDKW_RS07950	COG4269	membrane
UNDKW_RS08005	COG4221	oxidoreductase activity
UNDKW_RS08015	COG1028	Short-chain dehydrogenase reductase Sdr
UNDKW_RS08030	COG0582	viral genome integration into host DNA
UNDKW_RS08160	COG0583	DNA-binding transcription factor activity
UNDKW_RS08220	COG0835	chemotaxis
UNDKW_RS08225	COG0840	transmembrane signaling receptor activity
UNDKW_RS08270	COG1994	Peptidase M50
UNDKW_RS08280	COG0640	Transcriptional regulator
UNDKW_RS08295	COG1234	tRNA 3'-trailer cleavage
UNDKW_RS08325	COG3483	tryptophan 2,3-dioxygenase activity
UNDKW_RS08335	COG1522	sequence-specific DNA binding
UNDKW_RS08350	COG1459	type II secretion system
UNDKW_RS08370	COG0728	peptidoglycan biosynthetic process
UNDKW_RS08390	COG4676	Protein conserved in bacteria
UNDKW_RS08395	COG4676	Protein conserved in bacteria
UNDKW_RS08400	COG5445	Predicted secreted protein (DUF2300)
UNDKW_RS08405	COG2373	Large extracellular alpha-helical protein
UNDKW_RS08415	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
UNDKW_RS08425	COG2378	regulation of single-species biofilm formation
UNDKW_RS08430	COG3474	cytochrome
UNDKW_RS08455	COG0583	DNA-binding transcription factor activity
UNDKW_RS08470	COG3123	guanosine phosphorylase activity
UNDKW_RS08475	COG0137	argininosuccinate synthase activity
UNDKW_RS08480	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
UNDKW_RS08520	COG1162	GTPase activity
UNDKW_RS08525	COG2154	pterin-4-alpha-carbinolamine dehydratase
UNDKW_RS08530	COG0501	Belongs to the peptidase M48B family
UNDKW_RS08535	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
UNDKW_RS08570	COG1058	Belongs to the CinA family
UNDKW_RS08570	COG1546	Belongs to the CinA family
UNDKW_RS08595	COG4977	sequence-specific DNA binding
UNDKW_RS08595	COG1917	Cupin 2, conserved barrel domain protein
UNDKW_RS08610	COG0745	RESPONSE REGULATOR receiver
UNDKW_RS08615	COG0642	Histidine kinase
UNDKW_RS08640	COG3706	GGDEF domain
UNDKW_RS08685	COG1028	Short-chain dehydrogenase reductase Sdr
UNDKW_RS08705	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
UNDKW_RS08710	COG2986	histidine ammonia-lyase
UNDKW_RS08720	COG1228	amidohydrolase
UNDKW_RS08735	COG0745	RESPONSE REGULATOR receiver
UNDKW_RS08745	COG4589	Belongs to the CDS family
UNDKW_RS08750	COG2267	carboxylic ester hydrolase activity
UNDKW_RS08755	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
UNDKW_RS08770	COG4221	oxidoreductase activity
UNDKW_RS08800	COG0268	Binds directly to 16S ribosomal RNA
UNDKW_RS08840	COG1278	Cold shock
UNDKW_RS08845	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
UNDKW_RS08850	COG0542	response to heat
UNDKW_RS08865	COG1741	Belongs to the pirin family
UNDKW_RS08880	COG0756	dUTP diphosphatase activity
UNDKW_RS08885	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
UNDKW_RS08890	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
UNDKW_RS08895	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
UNDKW_RS08900	COG0196	riboflavin kinase activity
UNDKW_RS08910	COG2813	Specifically methylates the guanine in position
UNDKW_RS08945	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
UNDKW_RS08955	COG1385	rRNA (uridine-N3-)-methyltransferase activity
UNDKW_RS08965	COG0754	glutathionylspermidine amidase activity
UNDKW_RS08975	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
UNDKW_RS08980	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
UNDKW_RS09000	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
UNDKW_RS09005	COG0681	Belongs to the peptidase S26 family
UNDKW_RS09030	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
UNDKW_RS09035	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
UNDKW_RS09040	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
UNDKW_RS09055	COG4206	TonB-dependent receptor
UNDKW_RS09060	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
UNDKW_RS09065	COG1120	ATPase activity
UNDKW_RS09075	COG1797	cobyrinic acid a,c-diamide synthase activity
UNDKW_RS09085	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
UNDKW_RS09095	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
UNDKW_RS09105	COG1492	cobalamin metabolic process
UNDKW_RS09125	COG4771	TonB-dependent receptor
UNDKW_RS09160	COG0513	Belongs to the DEAD box helicase family
UNDKW_RS09165	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
UNDKW_RS09195	COG0601	transmembrane transport
UNDKW_RS09200	COG4166	transmembrane transport
UNDKW_RS09205	COG4166	transmembrane transport
UNDKW_RS09205	COG4166	transmembrane transport
UNDKW_RS09235	COG3706	GGDEF domain
UNDKW_RS09260	COG0700	Nucleoside recognition
UNDKW_RS09270	COG0402	S-adenosylhomocysteine deaminase activity
UNDKW_RS09280	COG0625	glutathione transferase activity
UNDKW_RS09285	COG0784	Response regulator, receiver
UNDKW_RS09285	COG3437	response regulator, receiver
UNDKW_RS09290	COG3852	Histidine kinase
UNDKW_RS09330	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
UNDKW_RS09330	COG4651	solute:proton antiporter activity
UNDKW_RS09380	COG0174	glutamine synthetase
UNDKW_RS09390	COG3852	Histidine kinase
UNDKW_RS09400	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
UNDKW_RS09410	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
UNDKW_RS09435	COG3145	DNA-N1-methyladenine dioxygenase activity
UNDKW_RS09470	COG3327	negative regulation of DNA-templated transcription, initiation
UNDKW_RS09475	COG3396	Phenylacetate-CoA oxygenase
UNDKW_RS09480	COG3460	Phenylacetate-CoA oxygenase
UNDKW_RS09485	COG3396	Phenylacetate-CoA oxygenase
UNDKW_RS09490	COG2151	metal-sulfur cluster biosynthetic enzyme
UNDKW_RS09495	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
UNDKW_RS09500	COG1024	Enoyl-CoA hydratase
UNDKW_RS09505	COG2050	protein possibly involved in aromatic compounds catabolism
UNDKW_RS09515	COG0183	Belongs to the thiolase family
UNDKW_RS09525	COG2030	dehydratase
UNDKW_RS09525	COG1012	belongs to the aldehyde dehydrogenase family
UNDKW_RS09530	COG4191	Histidine kinase
UNDKW_RS09535	COG3158	transport of potassium into the cell
UNDKW_RS09555	COG1214	PFAM Peptidase M22, glycoprotease
UNDKW_RS09565	COG1573	uracil-dna glycosylase
UNDKW_RS09575	COG0477	Major facilitator Superfamily
UNDKW_RS09590	COG1562	ergosterol biosynthetic process
UNDKW_RS09630	COG0544	peptidyl-prolyl cis-trans isomerase activity
UNDKW_RS09635	COG0740	serine-type endopeptidase activity
UNDKW_RS09640	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
UNDKW_RS09645	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
UNDKW_RS09650	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
UNDKW_RS09655	COG0360	Binds together with S18 to 16S ribosomal RNA
UNDKW_RS09665	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
UNDKW_RS09670	COG0359	binds to the 23S rRNA
UNDKW_RS09675	COG0305	Participates in initiation and elongation during chromosome replication
UNDKW_RS09685	COG0306	phosphate transporter
UNDKW_RS09705	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
UNDKW_RS09710	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
UNDKW_RS09725	COG0473	3-isopropylmalate dehydrogenase activity
UNDKW_RS09730	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
UNDKW_RS09740	COG0101	tRNA pseudouridine synthase activity
UNDKW_RS09745	COG0481	GTPase activity
UNDKW_RS09750	COG0681	Belongs to the peptidase S26 family
UNDKW_RS09765	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
UNDKW_RS09770	COG1381	Involved in DNA repair and RecF pathway recombination
UNDKW_RS09775	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
UNDKW_RS09780	COG0736	holo-[acyl-carrier-protein] synthase activity
UNDKW_RS09790	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
UNDKW_RS09890	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
UNDKW_RS09895	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
UNDKW_RS09945	COG2755	lipolytic protein G-D-S-L family
UNDKW_RS09945	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
UNDKW_RS09960	COG4783	chaperone-mediated protein folding
UNDKW_RS09985	COG2814	Major facilitator Superfamily
UNDKW_RS09990	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
UNDKW_RS09995	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
UNDKW_RS10015	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
UNDKW_RS10020	COG1360	Flagellar Motor Protein
UNDKW_RS10040	COG1815	bacterial-type flagellum-dependent cell motility
UNDKW_RS10045	COG1558	bacterial-type flagellum-dependent cell motility
UNDKW_RS10060	COG4787	bacterial-type flagellum-dependent cell motility
UNDKW_RS10070	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
UNDKW_RS10075	COG1706	bacterial-type flagellum-dependent cell motility
UNDKW_RS10085	COG1256	bacterial-type flagellum assembly
UNDKW_RS10105	COG1297	OPT oligopeptide transporter protein
UNDKW_RS10115	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
UNDKW_RS10120	COG3104	oligopeptide transport
UNDKW_RS10125	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
UNDKW_RS10140	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
UNDKW_RS10145	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
UNDKW_RS10150	COG0436	Aminotransferase
UNDKW_RS10160	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
UNDKW_RS10175	COG3622	Belongs to the hyi family
UNDKW_RS10180	COG2130	NADP-dependent
UNDKW_RS10210	COG1988	membrane-bound metal-dependent
UNDKW_RS10215	COG0521	Mo-molybdopterin cofactor biosynthetic process
UNDKW_RS10220	COG3028	Belongs to the UPF0307 family
UNDKW_RS10225	COG0312	modulator of DNA gyrase
UNDKW_RS10250	COG0683	leucine binding
UNDKW_RS10255	COG0165	Argininosuccinate lyase
UNDKW_RS10260	COG3275	phosphorelay sensor kinase activity
UNDKW_RS10280	COG1611	Belongs to the LOG family
UNDKW_RS10285	COG0784	Response regulator, receiver
UNDKW_RS10285	COG0835	chemotaxis
UNDKW_RS10300	COG3590	peptidase
UNDKW_RS10305	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
UNDKW_RS10345	COG1136	(ABC) transporter
UNDKW_RS10350	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
UNDKW_RS10370	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
UNDKW_RS10375	COG3278	Belongs to the heme-copper respiratory oxidase family
UNDKW_RS10410	COG0635	Involved in the biosynthesis of porphyrin-containing compound
UNDKW_RS10445	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
UNDKW_RS10450	COG2201	protein-glutamate methylesterase activity
UNDKW_RS10470	COG3214	Protein conserved in bacteria
UNDKW_RS10480	COG0181	hydroxymethylbilane synthase activity
UNDKW_RS10490	COG2959	enzyme of heme biosynthesis
UNDKW_RS10500	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
UNDKW_RS10505	COG0515	serine threonine protein kinase
UNDKW_RS10505	COG2815	serine threonine protein kinase
UNDKW_RS10515	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
UNDKW_RS10515	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
UNDKW_RS10520	COG0347	Belongs to the P(II) protein family
UNDKW_RS10530	COG2840	Smr protein MutS2
UNDKW_RS10535	COG0492	ferredoxin-NADP+ reductase activity
UNDKW_RS10540	COG1674	ftsk spoiiie
UNDKW_RS10545	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
UNDKW_RS10550	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
UNDKW_RS10560	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
UNDKW_RS10565	COG5001	Diguanylate cyclase
UNDKW_RS10565	COG3300	MHYT domain
UNDKW_RS10625	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
UNDKW_RS10625	COG2755	lipolytic protein G-D-S-L family
UNDKW_RS10630	COG3128	pkhd-type hydroxylase
UNDKW_RS10635	COG4774	siderophore transport
UNDKW_RS10645	COG0303	'Molybdopterin
UNDKW_RS10650	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
UNDKW_RS10655	COG0314	molybdopterin synthase activity
UNDKW_RS10660	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
UNDKW_RS10680	COG0542	response to heat
UNDKW_RS10695	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
UNDKW_RS10715	COG0084	hydrolase, TatD family'
UNDKW_RS10725	COG2267	carboxylic ester hydrolase activity
UNDKW_RS10735	COG0504	CTP synthase activity
UNDKW_RS10740	COG0148	phosphopyruvate hydratase activity
UNDKW_RS10770	COG0411	ABC transporter
UNDKW_RS10800	COG1028	Short-chain dehydrogenase reductase Sdr
UNDKW_RS10810	COG1024	Enoyl-CoA hydratase
UNDKW_RS10815	COG1960	acyl-CoA dehydrogenase activity
UNDKW_RS10830	COG1250	3-hydroxyacyl-CoA dehydrogenase
UNDKW_RS10835	COG1960	acyl-CoA dehydrogenase activity
UNDKW_RS10845	COG1960	acyl-CoA dehydrogenase activity
UNDKW_RS10855	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
UNDKW_RS10860	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
UNDKW_RS10865	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
UNDKW_RS10875	COG1804	L-carnitine dehydratase bile acid-inducible protein F
UNDKW_RS10880	COG2095	MarC family integral membrane protein
UNDKW_RS10885	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
UNDKW_RS10975	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
UNDKW_RS10980	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
UNDKW_RS10985	COG4942	peptidase
UNDKW_RS10985	COG1388	LysM domain
UNDKW_RS10995	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
UNDKW_RS11000	COG0105	UTP biosynthetic process
UNDKW_RS11005	COG0820	rRNA (adenine-C2-)-methyltransferase activity
UNDKW_RS11015	COG1426	Protein conserved in bacteria
UNDKW_RS11020	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
UNDKW_RS11025	COG0124	histidyl-tRNA synthetase
UNDKW_RS11040	COG1160	GTP binding
UNDKW_RS11045	COG1923	regulation of RNA biosynthetic process
UNDKW_RS11050	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
UNDKW_RS11055	COG0330	HflC and HflK could
UNDKW_RS11060	COG0330	HflC and HflK could
UNDKW_RS11065	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
UNDKW_RS11070	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
UNDKW_RS11075	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
UNDKW_RS11090	COG0557	exoribonuclease II activity
UNDKW_RS11095	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
UNDKW_RS11100	COG1045	serine acetyltransferase
UNDKW_RS11105	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
UNDKW_RS11105	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
UNDKW_RS11120	COG1338	Plays a role in the flagellum-specific transport system
UNDKW_RS11130	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
UNDKW_RS11150	COG2882	bacterial-type flagellum organization
UNDKW_RS11155	COG1157	protein secretion by the type III secretion system
UNDKW_RS11165	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
UNDKW_RS11175	COG1677	Flagellar hook-basal body complex protein FliE
UNDKW_RS11180	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
UNDKW_RS11185	COG2257	FlhB HrpN YscU SpaS Family
UNDKW_RS11205	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
UNDKW_RS11205	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
UNDKW_RS11230	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
UNDKW_RS11265	COG3706	GGDEF domain
UNDKW_RS11270	COG2197	response regulator
UNDKW_RS11285	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
UNDKW_RS11290	COG1758	RNA polymerase activity
UNDKW_RS11300	COG1561	YicC-like family, N-terminal region
UNDKW_RS11305	COG0515	serine threonine protein kinase
UNDKW_RS11305	COG3266	domain, Protein
UNDKW_RS11310	COG0631	protein serine/threonine phosphatase activity
UNDKW_RS11320	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
UNDKW_RS11325	COG0635	Involved in the biosynthesis of porphyrin-containing compound
UNDKW_RS11415	COG2165	general secretion pathway protein
UNDKW_RS11420	COG4968	Prepilin-type N-terminal cleavage methylation domain
UNDKW_RS11430	COG3401	FG-GAP repeat protein
UNDKW_RS11500	COG0277	FAD linked oxidase domain protein
UNDKW_RS11505	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
UNDKW_RS11510	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
UNDKW_RS11525	COG2204	response regulator
UNDKW_RS11540	COG5001	Diguanylate cyclase
UNDKW_RS11540	COG1716	ATPase activity
UNDKW_RS11545	COG4191	Histidine kinase
UNDKW_RS11565	COG0411	ABC transporter
UNDKW_RS11575	COG0829	nickel cation binding
UNDKW_RS11625	COG0831	urea catabolic process
UNDKW_RS11630	COG0832	Belongs to the urease beta subunit family
UNDKW_RS11635	COG0804	urea catabolic process
UNDKW_RS11640	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
UNDKW_RS11645	COG0830	nickel cation binding
UNDKW_RS11650	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
UNDKW_RS11660	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
UNDKW_RS11680	COG1012	belongs to the aldehyde dehydrogenase family
UNDKW_RS11695	COG1309	transcriptional regulator
UNDKW_RS11705	COG1804	L-carnitine dehydratase bile acid-inducible protein F
UNDKW_RS11710	COG4999	Histidine kinase
UNDKW_RS11710	COG3850	Histidine kinase
UNDKW_RS11710	COG3437	response regulator, receiver
UNDKW_RS11710	COG2205	protein histidine kinase activity
UNDKW_RS11715	COG1228	amidohydrolase
UNDKW_RS11720	COG1448	Aminotransferase
UNDKW_RS11760	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
UNDKW_RS11775	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
UNDKW_RS11780	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
UNDKW_RS11800	COG2850	peptidyl-arginine hydroxylation
UNDKW_RS11805	COG1047	Peptidyl-prolyl cis-trans
UNDKW_RS11810	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
UNDKW_RS11820	COG0513	Belongs to the DEAD box helicase family
UNDKW_RS11840	COG0625	glutathione transferase activity
UNDKW_RS11845	COG0631	protein serine/threonine phosphatase activity
UNDKW_RS11855	COG1199	ATP-dependent helicase activity
UNDKW_RS11860	COG3590	peptidase
UNDKW_RS11865	COG4608	Belongs to the ABC transporter superfamily
UNDKW_RS11870	COG0444	Belongs to the ABC transporter superfamily
UNDKW_RS11875	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
UNDKW_RS11880	COG0601	transmembrane transport
UNDKW_RS11885	COG0747	negative chemotaxis
UNDKW_RS11910	COG1136	(ABC) transporter
UNDKW_RS11930	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
UNDKW_RS11935	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
UNDKW_RS11940	COG0726	polysaccharide deacetylase
UNDKW_RS11945	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
UNDKW_RS11945	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
UNDKW_RS11950	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
UNDKW_RS11950	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
UNDKW_RS11955	COG0463	Glycosyl transferase, family 2
UNDKW_RS11960	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
UNDKW_RS11965	COG2076	Multidrug Resistance protein
UNDKW_RS11985	COG0436	Aminotransferase
UNDKW_RS12015	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
UNDKW_RS12035	COG1247	-acetyltransferase
UNDKW_RS12040	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
UNDKW_RS12075	COG3706	GGDEF domain
UNDKW_RS12085	COG1024	Enoyl-CoA hydratase
UNDKW_RS12085	COG1250	3-hydroxyacyl-CoA dehydrogenase
UNDKW_RS12090	COG0488	(ABC) transporter
UNDKW_RS12150	COG1960	acyl-CoA dehydrogenase activity
UNDKW_RS12160	COG0560	Phosphoserine phosphatase
UNDKW_RS12165	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
UNDKW_RS12175	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
UNDKW_RS12185	COG1047	Peptidyl-prolyl cis-trans
UNDKW_RS12190	COG0484	heat shock protein binding
UNDKW_RS12230	COG1979	alcohol dehydrogenase
UNDKW_RS12235	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
UNDKW_RS12245	COG1399	metal-binding, possibly nucleic acid-binding protein
UNDKW_RS12250	COG0333	Belongs to the bacterial ribosomal protein bL32 family
UNDKW_RS12255	COG0416	fatty acid biosynthetic process
UNDKW_RS12275	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
UNDKW_RS12280	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
UNDKW_RS12305	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
UNDKW_RS12315	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
UNDKW_RS12320	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
UNDKW_RS12325	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
UNDKW_RS12395	COG1902	pentaerythritol trinitrate reductase activity
UNDKW_RS12410	COG3228	Belongs to the MtfA family
UNDKW_RS12415	COG0488	(ABC) transporter
UNDKW_RS12420	COG2890	protein-(glutamine-N5) methyltransferase activity
UNDKW_RS12425	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
UNDKW_RS12430	COG1393	Belongs to the ArsC family
UNDKW_RS12440	COG2171	N-acyltransferase activity
UNDKW_RS12460	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
UNDKW_RS12465	COG1210	Utp--glucose-1-phosphate uridylyltransferase
UNDKW_RS12470	COG0242	peptide deformylase activity
UNDKW_RS12475	COG1187	pseudouridine synthase activity
UNDKW_RS12480	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
UNDKW_RS12485	COG0024	Methionine aminopeptidase
UNDKW_RS12490	COG0052	Belongs to the universal ribosomal protein uS2 family
UNDKW_RS12495	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
UNDKW_RS12500	COG0528	UMP kinase activity
UNDKW_RS12505	COG0233	cytoplasmic translational termination
UNDKW_RS12510	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
UNDKW_RS12515	COG0575	Belongs to the CDS family
UNDKW_RS12520	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
UNDKW_RS12525	COG0750	zinc metalloprotease
UNDKW_RS12540	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
UNDKW_RS12545	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
UNDKW_RS12550	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
UNDKW_RS12555	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
UNDKW_RS12560	COG0084	hydrolase, TatD family'
UNDKW_RS12565	COG0666	response to abiotic stimulus
UNDKW_RS12575	COG1116	anion transmembrane transporter activity
UNDKW_RS12580	COG0587	DNA-directed DNA polymerase activity
UNDKW_RS12660	COG1858	cytochrome C peroxidase
UNDKW_RS12760	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
UNDKW_RS12765	COG0010	Belongs to the arginase family
UNDKW_RS12775	COG2264	protein methyltransferase activity
UNDKW_RS12790	COG0501	Belongs to the peptidase M48B family
UNDKW_RS12800	COG0697	spore germination
UNDKW_RS12805	COG0625	glutathione transferase activity
UNDKW_RS12820	COG1960	acyl-CoA dehydrogenase activity
UNDKW_RS12825	COG1960	acyl-CoA dehydrogenase activity
UNDKW_RS12830	COG1012	belongs to the aldehyde dehydrogenase family
UNDKW_RS12830	COG2030	dehydratase
UNDKW_RS12855	COG2954	triphosphatase activity
UNDKW_RS12860	COG2866	Carboxypeptidase
UNDKW_RS12870	COG3507	Belongs to the glycosyl hydrolase 43 family
UNDKW_RS12875	COG3534	alpha-L-arabinofuranosidase
UNDKW_RS12895	COG2755	lipolytic protein G-D-S-L family
UNDKW_RS12920	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
UNDKW_RS12935	COG4952	isomerase
UNDKW_RS12940	COG1028	Short-chain dehydrogenase reductase Sdr
UNDKW_RS12940	COG3347	Dehydrogenase
UNDKW_RS12950	COG1879	ABC-type sugar transport system periplasmic component
UNDKW_RS12955	COG1129	ABC transporter
UNDKW_RS12960	COG1172	Belongs to the binding-protein-dependent transport system permease family
UNDKW_RS12965	COG1172	Belongs to the binding-protein-dependent transport system permease family
UNDKW_RS12975	COG3940	Belongs to the glycosyl hydrolase 43 family
UNDKW_RS12990	COG1028	Short-chain dehydrogenase reductase Sdr
UNDKW_RS13000	COG1129	ABC transporter
UNDKW_RS13015	COG0800	Aldolase
UNDKW_RS13020	COG3734	2-keto-3-deoxy-galactonokinase
UNDKW_RS13025	COG4948	Mandelate Racemase Muconate Lactonizing
UNDKW_RS13040	COG3401	FG-GAP repeat protein
UNDKW_RS13055	COG2755	lipolytic protein G-D-S-L family
UNDKW_RS13060	COG2755	lipolytic protein G-D-S-L family
UNDKW_RS13100	COG3813	Protein conserved in bacteria
UNDKW_RS13115	COG4372	Transposase
UNDKW_RS13145	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
UNDKW_RS13150	COG0243	molybdopterin cofactor binding
UNDKW_RS13170	COG1760	l-serine dehydratase
UNDKW_RS13200	COG3829	transcription factor binding
UNDKW_RS13200	COG3290	protein histidine kinase activity
UNDKW_RS13205	COG1012	belongs to the aldehyde dehydrogenase family
UNDKW_RS13220	COG1104	cysteine desulfurase activity
UNDKW_RS13225	COG0822	iron-sulfur transferase activity
UNDKW_RS13235	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
UNDKW_RS13240	COG0443	Heat shock 70 kDa protein
UNDKW_RS13245	COG0633	Ferredoxin
UNDKW_RS13250	COG2975	iron-sulfur cluster assembly
UNDKW_RS13260	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
UNDKW_RS13275	COG3713	MltA-interacting MipA family protein
UNDKW_RS13280	COG1982	Orn Lys Arg decarboxylase major
UNDKW_RS13300	COG2066	Belongs to the glutaminase family
UNDKW_RS13305	COG0717	Belongs to the dCTP deaminase family
UNDKW_RS13310	COG1032	radical SAM domain protein
UNDKW_RS13325	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
UNDKW_RS13330	COG1132	(ABC) transporter
UNDKW_RS13340	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
UNDKW_RS13360	COG0596	Alpha beta hydrolase
UNDKW_RS13365	COG1280	lysine exporter protein (LysE YggA)
UNDKW_RS13380	COG0529	Catalyzes the synthesis of activated sulfate
UNDKW_RS13385	COG0840	transmembrane signaling receptor activity
UNDKW_RS13400	COG0824	Thioesterase
UNDKW_RS13405	COG0596	Alpha beta hydrolase
UNDKW_RS13410	COG1028	Short-chain dehydrogenase reductase Sdr
UNDKW_RS13420	COG2130	NADP-dependent
UNDKW_RS13440	COG1960	acyl-CoA dehydrogenase activity
UNDKW_RS13445	COG0183	Belongs to the thiolase family
UNDKW_RS13455	COG1619	proteins homologs of microcin C7 resistance protein MccF
UNDKW_RS13465	COG0720	synthase
UNDKW_RS13470	COG0602	queuosine metabolic process
UNDKW_RS13480	COG0518	GMP synthase (glutamine-hydrolyzing) activity
UNDKW_RS13480	COG0519	Catalyzes the synthesis of GMP from XMP
UNDKW_RS13490	COG0517	IMP dehydrogenase activity
UNDKW_RS13490	COG0516	GMP reductase activity
UNDKW_RS13500	COG2914	Belongs to the UPF0125 (RnfH) family
UNDKW_RS13510	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
UNDKW_RS13520	COG0745	RESPONSE REGULATOR receiver
UNDKW_RS13525	COG2205	protein histidine kinase activity
UNDKW_RS13540	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
UNDKW_RS13545	COG0436	Aminotransferase
UNDKW_RS13565	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
UNDKW_RS13570	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
UNDKW_RS13580	COG0508	dehydrogenase complex catalyzes the overall conversion of
UNDKW_RS13585	COG0567	Dehydrogenase, E1 component
UNDKW_RS13590	COG0372	Belongs to the citrate synthase family
UNDKW_RS13595	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
UNDKW_RS13600	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
UNDKW_RS13605	COG1053	succinate dehydrogenase
UNDKW_RS13615	COG2009	succinate dehydrogenase
UNDKW_RS13620	COG2188	Transcriptional regulator
UNDKW_RS13640	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
UNDKW_RS13650	COG0626	cystathionine gamma-synthase activity
UNDKW_RS13665	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
UNDKW_RS13675	COG1028	Short-chain dehydrogenase reductase Sdr
UNDKW_RS13680	COG3243	poly(R)-hydroxyalkanoic acid synthase
UNDKW_RS13695	COG0564	pseudouridine synthase activity
UNDKW_RS13705	COG3022	response to hydroperoxide
UNDKW_RS13715	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
UNDKW_RS13720	COG0643	Histidine kinase
UNDKW_RS13720	COG0784	Response regulator, receiver
UNDKW_RS13720	COG2198	Histidine kinase
UNDKW_RS13725	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
UNDKW_RS13730	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
UNDKW_RS13735	COG2917	probably involved in intracellular septation
UNDKW_RS13745	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
UNDKW_RS13755	COG0047	phosphoribosylformylglycinamidine synthase activity
UNDKW_RS13755	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
UNDKW_RS13760	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
UNDKW_RS13770	COG0745	RESPONSE REGULATOR receiver
UNDKW_RS13775	COG2201	protein-glutamate methylesterase activity
UNDKW_RS13780	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
UNDKW_RS13790	COG0840	transmembrane signaling receptor activity
UNDKW_RS13795	COG0835	chemotaxis
UNDKW_RS13800	COG2198	Histidine kinase
UNDKW_RS13800	COG0643	Histidine kinase
UNDKW_RS13805	COG0745	RESPONSE REGULATOR receiver
UNDKW_RS13815	COG1360	Flagellar Motor Protein
UNDKW_RS13845	COG0037	tRNA processing
UNDKW_RS13850	COG0825	malonyl-CoA metabolic process
UNDKW_RS13855	COG3063	Type IV pilus biogenesis stability protein PilW
UNDKW_RS13870	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
UNDKW_RS13875	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
UNDKW_RS13880	COG4181	ATPase activity
UNDKW_RS13890	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
UNDKW_RS13900	COG2217	Heavy metal translocating P-type atpase
UNDKW_RS13920	COG0546	phosphoglycolate phosphatase activity
UNDKW_RS13925	COG0564	pseudouridine synthase activity
UNDKW_RS13930	COG1530	ribonuclease E activity
UNDKW_RS13940	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
UNDKW_RS13945	COG0746	molybdenum cofactor guanylyltransferase activity
UNDKW_RS13950	COG0303	'Molybdopterin
UNDKW_RS13955	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
UNDKW_RS13975	COG5001	Diguanylate cyclase
UNDKW_RS13975	COG3447	MASE1 domain protein
UNDKW_RS13975	COG5002	protein histidine kinase activity
UNDKW_RS13985	COG0789	Transcriptional regulator
UNDKW_RS13990	COG1322	Protein conserved in bacteria
UNDKW_RS14000	COG0625	glutathione transferase activity
UNDKW_RS14005	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
UNDKW_RS14015	COG0596	Alpha beta hydrolase
UNDKW_RS14020	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
UNDKW_RS14040	COG2833	Protein of unknown function (DUF455)
UNDKW_RS14050	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
UNDKW_RS14075	COG3852	Histidine kinase
UNDKW_RS14085	COG1131	(ABC) transporter
UNDKW_RS14095	COG1164	Oligoendopeptidase f
UNDKW_RS14110	COG0697	spore germination
UNDKW_RS14115	COG1643	Atp-dependent helicase
UNDKW_RS14125	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
UNDKW_RS14125	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
UNDKW_RS14130	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
UNDKW_RS14135	COG0288	reversible hydration of carbon dioxide
UNDKW_RS14140	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
UNDKW_RS14150	COG3012	SEC-C Motif Domain Protein
UNDKW_RS14150	COG3318	Belongs to the UPF0149 family
UNDKW_RS14165	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
UNDKW_RS14170	COG0492	ferredoxin-NADP+ reductase activity
UNDKW_RS14180	COG3437	response regulator, receiver
UNDKW_RS14180	COG2205	protein histidine kinase activity
UNDKW_RS14180	COG3850	Histidine kinase
UNDKW_RS14180	COG4999	Histidine kinase
UNDKW_RS14190	COG2878	Part of a membrane complex involved in electron transport
UNDKW_RS14195	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
UNDKW_RS14200	COG0778	Nitroreductase
UNDKW_RS14210	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
UNDKW_RS14215	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
UNDKW_RS14225	COG1994	Peptidase M50
UNDKW_RS14230	COG0009	L-threonylcarbamoyladenylate synthase
UNDKW_RS14235	COG0501	Belongs to the peptidase M48B family
UNDKW_RS14240	COG0613	PHP domain protein
UNDKW_RS14250	COG0842	Transport permease protein
UNDKW_RS14255	COG1131	(ABC) transporter
UNDKW_RS14270	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
UNDKW_RS14275	COG0285	dihydrofolate synthase activity
UNDKW_RS14280	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
UNDKW_RS14285	COG0159	tryptophan synthase activity
UNDKW_RS14290	COG0133	tryptophan synthase activity
UNDKW_RS14295	COG0135	phosphoribosylanthranilate isomerase activity
UNDKW_RS14310	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
UNDKW_RS14315	COG2224	Isocitrate lyase
UNDKW_RS14330	COG1216	Glycosyl transferase, family 2
UNDKW_RS14335	COG3206	protein involved in exopolysaccharide biosynthesis
UNDKW_RS14335	COG0489	protein tyrosine kinase activity
UNDKW_RS14350	COG1216	Glycosyl transferase, family 2
UNDKW_RS14350	COG1442	glycosyl transferase family 8
UNDKW_RS14355	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
UNDKW_RS14365	COG1295	ribonuclease BN
UNDKW_RS14380	COG0277	FAD linked oxidase domain protein
UNDKW_RS14385	COG0840	transmembrane signaling receptor activity
UNDKW_RS14390	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
UNDKW_RS14405	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
UNDKW_RS14415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
UNDKW_RS14420	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
UNDKW_RS14430	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
UNDKW_RS14435	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
UNDKW_RS14440	COG0505	Belongs to the CarA family
UNDKW_RS14445	COG3193	protein, possibly involved in utilization of glycolate and propanediol
UNDKW_RS14450	COG0791	NLP P60 protein
UNDKW_RS14455	COG1752	Esterase of the alpha-beta hydrolase superfamily
UNDKW_RS14480	COG0784	Response regulator, receiver
UNDKW_RS14480	COG2205	protein histidine kinase activity
UNDKW_RS14480	COG5002	protein histidine kinase activity
UNDKW_RS14510	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
UNDKW_RS14630	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
UNDKW_RS14635	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
UNDKW_RS14640	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
UNDKW_RS14650	COG0779	Required for maturation of 30S ribosomal subunits
UNDKW_RS14655	COG1187	pseudouridine synthase activity
UNDKW_RS14660	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
UNDKW_RS14690	COG0004	ammonium transporteR
UNDKW_RS14695	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
UNDKW_RS14700	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
UNDKW_RS14705	COG0167	dihydroorotate dehydrogenase activity
UNDKW_RS14710	COG0667	Aldo Keto reductase
UNDKW_RS14725	COG4682	membrane
UNDKW_RS14735	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
UNDKW_RS14750	COG0730	response to heat
UNDKW_RS14755	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
UNDKW_RS14765	COG0175	sulfate reduction
UNDKW_RS14775	COG2895	sulfate adenylyltransferase (ATP) activity
UNDKW_RS14780	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
UNDKW_RS14780	COG1648	precorrin-2 dehydrogenase activity
UNDKW_RS14800	COG0795	lipopolysaccharide-transporting ATPase activity
UNDKW_RS14805	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
UNDKW_RS14815	COG0708	Exodeoxyribonuclease III
UNDKW_RS14820	COG0840	transmembrane signaling receptor activity
UNDKW_RS14835	COG1132	(ABC) transporter
UNDKW_RS14840	COG0189	ligase activity
UNDKW_RS14840	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
UNDKW_RS14845	COG0189	ligase activity
UNDKW_RS14845	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
UNDKW_RS14855	COG0693	protein deglycase activity
UNDKW_RS14860	COG3706	GGDEF domain
UNDKW_RS14870	COG0556	nucleotide-excision repair
UNDKW_RS14895	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
UNDKW_RS14905	COG3128	pkhd-type hydroxylase
UNDKW_RS14915	COG4774	siderophore transport
UNDKW_RS14935	COG1309	transcriptional regulator
UNDKW_RS14940	COG0840	transmembrane signaling receptor activity
UNDKW_RS14950	COG0776	regulation of translation
UNDKW_RS14955	COG0072	phenylalanine-tRNA ligase activity
UNDKW_RS14955	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
UNDKW_RS14960	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
UNDKW_RS14965	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
UNDKW_RS14970	COG0291	Belongs to the bacterial ribosomal protein bL35 family
UNDKW_RS14975	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
UNDKW_RS14980	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
UNDKW_RS14990	COG1230	cation diffusion facilitator family transporter
UNDKW_RS15000	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
UNDKW_RS15005	COG0251	oxidation-reduction process
UNDKW_RS15015	COG1028	Short-chain dehydrogenase reductase Sdr
UNDKW_RS15035	COG4566	intracellular signal transduction
UNDKW_RS15045	COG1028	Short-chain dehydrogenase reductase Sdr
UNDKW_RS15070	COG1007	ATP synthesis coupled electron transport
UNDKW_RS15085	COG0713	ATP synthesis coupled electron transport
UNDKW_RS15095	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
UNDKW_RS15100	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
UNDKW_RS15105	COG1034	ATP synthesis coupled electron transport
UNDKW_RS15115	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
UNDKW_RS15120	COG0649	NAD binding
UNDKW_RS15125	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
UNDKW_RS15130	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
UNDKW_RS15135	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
UNDKW_RS15150	COG0149	triose-phosphate isomerase activity
UNDKW_RS15155	COG0604	alcohol dehydrogenase
UNDKW_RS15160	COG1185	polyribonucleotide nucleotidyltransferase activity
UNDKW_RS15165	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
UNDKW_RS15175	COG1183	phosphatidylcholine synthase activity
UNDKW_RS15190	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
UNDKW_RS15195	COG0440	acetolactate synthase activity
UNDKW_RS15200	COG0028	Belongs to the TPP enzyme family
UNDKW_RS15205	COG1595	DNA-templated transcription, initiation
UNDKW_RS15225	COG1309	transcriptional regulator
UNDKW_RS15245	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
UNDKW_RS15250	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
UNDKW_RS15300	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
UNDKW_RS15305	COG2885	chlorophyll binding
UNDKW_RS15310	COG0823	Involved in the tonB-independent uptake of proteins
UNDKW_RS15325	COG3038	cytochrome b561
UNDKW_RS15370	COG0697	spore germination
UNDKW_RS15380	COG0328	RNA-DNA hybrid ribonuclease activity
UNDKW_RS15390	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
UNDKW_RS15400	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
UNDKW_RS15440	COG0747	negative chemotaxis
UNDKW_RS15450	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
UNDKW_RS15475	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
UNDKW_RS15480	COG0564	pseudouridine synthase activity
UNDKW_RS15495	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
UNDKW_RS15495	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
UNDKW_RS15500	COG0489	protein tyrosine kinase activity
UNDKW_RS15545	COG3250	beta-galactosidase activity
UNDKW_RS15570	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
UNDKW_RS15570	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
UNDKW_RS15585	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
UNDKW_RS15605	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
UNDKW_RS15610	COG0581	inorganic phosphate transmembrane transporter activity
UNDKW_RS15615	COG0573	inorganic phosphate transmembrane transporter activity
UNDKW_RS15655	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
UNDKW_RS15660	COG3527	Alpha-acetolactate decarboxylase
UNDKW_RS15680	COG2010	Cytochrome c
UNDKW_RS15680	COG1529	Aldehyde oxidase and xanthine dehydrogenase
UNDKW_RS15690	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
UNDKW_RS15710	COG4206	TonB-dependent receptor
UNDKW_RS15730	COG2205	protein histidine kinase activity
UNDKW_RS15735	COG0745	RESPONSE REGULATOR receiver
UNDKW_RS15815	COG0527	aspartate kinase activity
UNDKW_RS15830	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
UNDKW_RS15835	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
UNDKW_RS15845	COG0583	DNA-binding transcription factor activity
UNDKW_RS15850	COG0840	transmembrane signaling receptor activity
UNDKW_RS15855	COG1278	Cold shock
UNDKW_RS15870	COG2050	protein possibly involved in aromatic compounds catabolism
UNDKW_RS15880	COG1250	3-hydroxyacyl-CoA dehydrogenase
UNDKW_RS15880	COG1024	Enoyl-CoA hydratase
UNDKW_RS15885	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
UNDKW_RS15895	COG2843	Capsule synthesis protein
UNDKW_RS15925	COG0583	DNA-binding transcription factor activity
UNDKW_RS15930	COG1752	Esterase of the alpha-beta hydrolase superfamily
UNDKW_RS15945	COG0840	transmembrane signaling receptor activity
UNDKW_RS16010	COG5001	Diguanylate cyclase
UNDKW_RS16010	COG4251	negative regulation of phosphorylation
UNDKW_RS16010	COG2203	Gaf domain
UNDKW_RS16010	COG3706	GGDEF domain
UNDKW_RS16015	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
UNDKW_RS16020	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
UNDKW_RS16025	COG3639	organic phosphonate transmembrane transporter activity
UNDKW_RS16030	COG3639	organic phosphonate transmembrane transporter activity
UNDKW_RS16035	COG1288	antiporter activity
UNDKW_RS16045	COG1737	Transcriptional regulator
UNDKW_RS16060	COG0840	transmembrane signaling receptor activity
UNDKW_RS16085	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
UNDKW_RS16085	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
UNDKW_RS16090	COG0509	glycine decarboxylation via glycine cleavage system
UNDKW_RS16095	COG0404	The glycine cleavage system catalyzes the degradation of glycine
UNDKW_RS16115	COG1132	(ABC) transporter
UNDKW_RS16120	COG1309	transcriptional regulator
UNDKW_RS16130	COG1574	metal-dependent hydrolase with the TIM-barrel fold
UNDKW_RS16175	COG3220	belongs to the UPF0276 family
UNDKW_RS16195	COG2703	oxygen carrier activity
UNDKW_RS16205	COG1763	Mo-molybdopterin cofactor biosynthetic process
UNDKW_RS16245	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
UNDKW_RS16250	COG0166	Belongs to the GPI family
UNDKW_RS16265	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
UNDKW_RS16270	COG0363	glucosamine-6-phosphate deaminase activity
UNDKW_RS16275	COG1737	Transcriptional regulator
UNDKW_RS16300	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
UNDKW_RS16305	COG0129	dihydroxy-acid dehydratase activity
UNDKW_RS16310	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
UNDKW_RS16315	COG0308	aminopeptidase N
UNDKW_RS16335	COG0697	spore germination
UNDKW_RS16345	COG0433	COG0433 Predicted ATPase
UNDKW_RS16350	COG0217	transcriptional regulatory protein
UNDKW_RS16355	COG0151	Belongs to the GarS family
UNDKW_RS16365	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
UNDKW_RS16370	COG0799	negative regulation of ribosome biogenesis
UNDKW_RS16375	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
UNDKW_RS16380	COG0424	maF-like protein
UNDKW_RS16385	COG1530	ribonuclease E activity
UNDKW_RS16400	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
UNDKW_RS16410	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
UNDKW_RS16415	COG0842	Transport permease protein
UNDKW_RS16420	COG1129	ABC transporter
UNDKW_RS16420	COG0842	Transport permease protein
UNDKW_RS16425	COG1129	ABC transporter
UNDKW_RS16425	COG0842	Transport permease protein
UNDKW_RS16440	COG3243	poly(R)-hydroxyalkanoic acid synthase
UNDKW_RS16450	COG3447	MASE1 domain protein
UNDKW_RS16450	COG5001	Diguanylate cyclase
UNDKW_RS16450	COG5002	protein histidine kinase activity
UNDKW_RS16460	COG0859	PFAM glycosyl transferase family 9
UNDKW_RS16495	COG3706	GGDEF domain
UNDKW_RS16500	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
UNDKW_RS16525	COG0583	DNA-binding transcription factor activity
UNDKW_RS16530	COG4336	lyase activity
UNDKW_RS16540	COG0071	Belongs to the small heat shock protein (HSP20) family
UNDKW_RS16600	COG0492	ferredoxin-NADP+ reductase activity
UNDKW_RS16605	COG4232	protein-disulfide reductase activity
UNDKW_RS16620	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
UNDKW_RS16665	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
UNDKW_RS16675	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
UNDKW_RS16725	COG3275	phosphorelay sensor kinase activity
UNDKW_RS16730	COG3279	Response regulator of the LytR AlgR family
UNDKW_RS16750	COG0840	transmembrane signaling receptor activity
UNDKW_RS16765	COG1172	Belongs to the binding-protein-dependent transport system permease family
UNDKW_RS16800	COG0284	orotidine-5'-phosphate decarboxylase activity
UNDKW_RS16805	COG1846	Transcriptional regulator
UNDKW_RS16810	COG1764	response to oxidative stress
UNDKW_RS16830	COG1999	signal sequence binding
UNDKW_RS16920	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
UNDKW_RS16930	COG0335	large ribosomal subunit rRNA binding
UNDKW_RS16935	COG0336	Belongs to the RNA methyltransferase TrmD family
UNDKW_RS16940	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
UNDKW_RS16945	COG0228	four-way junction DNA binding
UNDKW_RS16970	COG1178	ABC-type Fe3 transport system permease component
UNDKW_RS16980	COG3842	ATPase activity
UNDKW_RS16995	COG1960	acyl-CoA dehydrogenase activity
UNDKW_RS17010	COG0425	Belongs to the sulfur carrier protein TusA family
UNDKW_RS17020	COG1247	-acetyltransferase
UNDKW_RS17025	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
UNDKW_RS17050	COG1136	(ABC) transporter
UNDKW_RS17055	COG0789	Transcriptional regulator
UNDKW_RS17060	COG0584	glycerophosphoryl diester phosphodiesterase
UNDKW_RS17065	COG1804	L-carnitine dehydratase bile acid-inducible protein F
UNDKW_RS17070	COG3275	phosphorelay sensor kinase activity
UNDKW_RS17080	COG2153	protein acetylation
UNDKW_RS17090	COG3590	peptidase
UNDKW_RS17105	COG0318	PFAM AMP-dependent synthetase and ligase
UNDKW_RS17135	COG4941	Belongs to the sigma-70 factor family
UNDKW_RS17145	COG2764	glyoxalase bleomycin resistance protein dioxygenase
UNDKW_RS17150	COG3795	YCII-related domain
UNDKW_RS17175	COG1741	Belongs to the pirin family
UNDKW_RS17180	COG0583	DNA-binding transcription factor activity
UNDKW_RS17185	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
UNDKW_RS17220	COG1279	arginine transmembrane transporter activity
UNDKW_RS17240	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
UNDKW_RS17245	COG0237	dephospho-CoA kinase activity
UNDKW_RS17280	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
UNDKW_RS17285	COG0459	protein refolding
UNDKW_RS17305	COG2085	NADP oxidoreductase coenzyme F420-dependent
UNDKW_RS17345	COG0705	Rhomboid family
UNDKW_RS17385	COG1024	Enoyl-CoA hydratase
UNDKW_RS17460	COG0714	Associated with various cellular activities
UNDKW_RS17475	COG2951	lytic endotransglycosylase activity
UNDKW_RS17500	COG0583	DNA-binding transcription factor activity
UNDKW_RS17510	COG3384	dioxygenase
UNDKW_RS17515	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
UNDKW_RS17525	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
UNDKW_RS17535	COG0776	regulation of translation
UNDKW_RS17545	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
UNDKW_RS17550	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
UNDKW_RS17555	COG0287	Prephenate dehydrogenase
UNDKW_RS17560	COG1605	Chorismate mutase
UNDKW_RS17560	COG0077	Prephenate dehydratase
UNDKW_RS17565	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
UNDKW_RS17585	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
UNDKW_RS17610	COG4942	peptidase
UNDKW_RS17645	COG2010	Cytochrome c
UNDKW_RS17660	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
UNDKW_RS17680	COG4264	IucA IucC family
UNDKW_RS17705	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
UNDKW_RS17710	COG2091	lysine biosynthetic process via aminoadipic acid
UNDKW_RS17720	COG1366	Belongs to the anti-sigma-factor antagonist family
UNDKW_RS17725	COG1132	(ABC) transporter
UNDKW_RS17730	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
UNDKW_RS17735	COG0318	PFAM AMP-dependent synthetase and ligase
UNDKW_RS17740	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
UNDKW_RS17780	COG2172	sigma factor antagonist activity
UNDKW_RS17785	COG2208	phosphoserine phosphatase activity
UNDKW_RS17785	COG2770	Histidine kinase
UNDKW_RS17825	COG0583	DNA-binding transcription factor activity
UNDKW_RS17835	COG0583	DNA-binding transcription factor activity
UNDKW_RS17840	COG2015	COG2015, Alkyl sulfatase and related hydrolases
UNDKW_RS17870	COG1301	dicarboxylic acid transport
UNDKW_RS17880	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
UNDKW_RS17895	COG0826	peptidase U32
UNDKW_RS17935	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
UNDKW_RS17940	COG0840	transmembrane signaling receptor activity
UNDKW_RS17955	COG1968	undecaprenyl-diphosphatase activity
UNDKW_RS17960	COG0514	ATP-dependent DNA helicase (RecQ)
UNDKW_RS18000	COG2378	regulation of single-species biofilm formation
UNDKW_RS18025	COG2211	Major facilitator Superfamily
UNDKW_RS18035	COG0737	Belongs to the 5'-nucleotidase family
UNDKW_RS18040	COG2010	Cytochrome c
UNDKW_RS18060	COG4654	Cytochrome c, class I
UNDKW_RS18065	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
UNDKW_RS18075	COG0583	DNA-binding transcription factor activity
UNDKW_RS18095	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
UNDKW_RS18125	COG0492	ferredoxin-NADP+ reductase activity
UNDKW_RS18150	COG2076	Multidrug Resistance protein
UNDKW_RS18180	COG1131	(ABC) transporter
UNDKW_RS18205	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
UNDKW_RS18220	COG0220	tRNA (guanine-N7-)-methyltransferase activity
UNDKW_RS18360	COG1783	phage Terminase large subunit
UNDKW_RS18400	COG3720	iron ion transport
UNDKW_RS18405	COG4558	Periplasmic binding protein
UNDKW_RS18410	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
UNDKW_RS18415	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
UNDKW_RS18450	COG0583	DNA-binding transcription factor activity
UNDKW_RS18455	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
UNDKW_RS18465	COG3550	peptidyl-serine autophosphorylation
UNDKW_RS18480	COG3383	formate dehydrogenase (NAD+) activity
UNDKW_RS18510	COG1960	acyl-CoA dehydrogenase activity
UNDKW_RS18515	COG1024	Enoyl-CoA hydratase
UNDKW_RS18540	COG5002	protein histidine kinase activity
UNDKW_RS18540	COG3447	MASE1 domain protein
UNDKW_RS18540	COG5001	Diguanylate cyclase
UNDKW_RS18625	COG0840	transmembrane signaling receptor activity
UNDKW_RS18635	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
UNDKW_RS18655	COG0840	transmembrane signaling receptor activity
UNDKW_RS18690	COG0835	chemotaxis
UNDKW_RS18695	COG0840	transmembrane signaling receptor activity
UNDKW_RS18700	COG1228	amidohydrolase
UNDKW_RS18755	COG0815	Transfers the fatty acyl group on membrane lipoproteins
UNDKW_RS18795	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
UNDKW_RS18800	COG1702	phosphate starvation-inducible protein PhoH
UNDKW_RS18805	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
UNDKW_RS18815	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
UNDKW_RS18850	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
UNDKW_RS18890	COG0477	Major facilitator Superfamily
UNDKW_RS18990	COG0009	L-threonylcarbamoyladenylate synthase
UNDKW_RS18995	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
UNDKW_RS19000	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
UNDKW_RS19005	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
UNDKW_RS19020	COG0126	phosphoglycerate kinase activity
UNDKW_RS19055	COG0429	hydrolase of the alpha beta-hydrolase fold
UNDKW_RS19090	COG1752	Esterase of the alpha-beta hydrolase superfamily
UNDKW_RS19125	COG4783	chaperone-mediated protein folding
UNDKW_RS19130	COG0315	cyclic pyranopterin monophosphate synthase activity
UNDKW_RS19200	COG3307	-O-antigen
UNDKW_RS19260	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
UNDKW_RS19285	COG4106	trans-aconitate 2-methyltransferase activity
UNDKW_RS19330	COG0583	DNA-binding transcription factor activity
UNDKW_RS19355	COG0702	epimerase
UNDKW_RS19365	COG2814	Major facilitator Superfamily
UNDKW_RS19370	COG0583	DNA-binding transcription factor activity
UNDKW_RS19380	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
UNDKW_RS19395	COG0492	ferredoxin-NADP+ reductase activity
UNDKW_RS19405	COG1247	-acetyltransferase
UNDKW_RS19485	COG1942	4-Oxalocrotonate Tautomerase
UNDKW_RS19495	COG0583	DNA-binding transcription factor activity
UNDKW_RS19530	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
UNDKW_RS19540	COG4122	O-methyltransferase activity
UNDKW_RS19630	COG1595	DNA-templated transcription, initiation
UNDKW_RS19645	COG0531	amino acid
UNDKW_RS19650	COG4303	Ethanolamine ammonia lyase large subunit
UNDKW_RS19655	COG4302	ethanolamine ammonia-lyase activity
UNDKW_RS19675	COG1162	GTPase activity
UNDKW_RS19705	COG3038	cytochrome b561
UNDKW_RS19835	COG1191	sigma factor activity
UNDKW_RS19840	COG1338	Plays a role in the flagellum-specific transport system
UNDKW_RS19865	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
UNDKW_RS19880	COG1157	protein secretion by the type III secretion system
UNDKW_RS19900	COG1677	Flagellar hook-basal body complex protein FliE
UNDKW_RS19905	COG1558	bacterial-type flagellum-dependent cell motility
UNDKW_RS19915	COG1706	bacterial-type flagellum-dependent cell motility
UNDKW_RS19920	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
UNDKW_RS19930	COG4786	Flagellar basal body rod
UNDKW_RS19935	COG4786	Flagellar basal body rod
UNDKW_RS19940	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
UNDKW_RS19945	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
UNDKW_RS19950	COG1684	flagellar biosynthetic protein fliR
UNDKW_RS19955	COG1987	bacterial-type flagellum assembly
UNDKW_RS19980	COG4372	Transposase
UNDKW_RS19995	COG4974	Belongs to the 'phage' integrase family
UNDKW_RS20005	COG3620	sequence-specific DNA binding
UNDKW_RS20080	COG4974	Belongs to the 'phage' integrase family
UNDKW_RS20090	COG3620	sequence-specific DNA binding
UNDKW_RS20210	COG3385	transposase activity
UNDKW_RS20310	COG2267	carboxylic ester hydrolase activity
UNDKW_RS20330	COG0024	Methionine aminopeptidase
UNDKW_RS20340	COG0784	Response regulator, receiver
UNDKW_RS20350	COG4251	negative regulation of phosphorylation
UNDKW_RS20355	COG4191	Histidine kinase
UNDKW_RS20390	COG3458	cephalosporin-C deacetylase activity
UNDKW_RS20400	COG0793	Belongs to the peptidase S41A family
UNDKW_RS20405	COG0840	transmembrane signaling receptor activity
UNDKW_RS20410	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
UNDKW_RS20505	COG2207	Transcriptional regulator
UNDKW_RS20520	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
UNDKW_RS20520	COG3608	succinylglutamate desuccinylase aspartoacylase
UNDKW_RS20540	COG4628	conserved protein (DUF2132)
UNDKW_RS20580	COG0840	transmembrane signaling receptor activity
UNDKW_RS20590	COG1804	L-carnitine dehydratase bile acid-inducible protein F
UNDKW_RS20605	COG1301	dicarboxylic acid transport
UNDKW_RS20610	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
UNDKW_RS20615	COG1929	Belongs to the glycerate kinase type-1 family
UNDKW_RS20645	COG1609	Transcriptional regulator
UNDKW_RS20655	COG1116	anion transmembrane transporter activity
UNDKW_RS20690	COG1574	metal-dependent hydrolase with the TIM-barrel fold
UNDKW_RS20695	COG1335	isochorismatase
UNDKW_RS20700	COG0753	catalase activity
UNDKW_RS20720	COG2197	response regulator
UNDKW_RS20730	COG0625	glutathione transferase activity
UNDKW_RS20740	COG3507	Belongs to the glycosyl hydrolase 43 family
UNDKW_RS20755	COG1609	Transcriptional regulator
UNDKW_RS20765	COG4948	Mandelate Racemase Muconate Lactonizing
UNDKW_RS20780	COG2207	Transcriptional regulator
UNDKW_RS20780	COG1609	Transcriptional regulator
UNDKW_RS20785	COG1472	Belongs to the glycosyl hydrolase 3 family
UNDKW_RS20790	COG4214	carbohydrate transport
UNDKW_RS20795	COG1129	ABC transporter
UNDKW_RS20800	COG4213	ABC transporter substrate-binding protein
UNDKW_RS20805	COG0129	dihydroxy-acid dehydratase activity
UNDKW_RS20835	COG4771	TonB-dependent receptor
UNDKW_RS20885	COG0604	alcohol dehydrogenase
UNDKW_RS20885	COG3321	synthase
UNDKW_RS20930	COG5002	protein histidine kinase activity
UNDKW_RS20930	COG2205	protein histidine kinase activity
UNDKW_RS20930	COG0784	Response regulator, receiver
UNDKW_RS20965	COG0583	DNA-binding transcription factor activity
UNDKW_RS20980	COG1522	sequence-specific DNA binding
UNDKW_RS20985	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
UNDKW_RS20990	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
UNDKW_RS21005	COG1280	lysine exporter protein (LysE YggA)
UNDKW_RS21035	COG1131	(ABC) transporter
UNDKW_RS21040	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
UNDKW_RS21055	COG0017	Asparaginyl-tRNA synthetase
UNDKW_RS21105	COG5001	Diguanylate cyclase
UNDKW_RS21125	COG2995	paraquat-inducible protein a
UNDKW_RS21130	COG2995	paraquat-inducible protein a
UNDKW_RS21135	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
UNDKW_RS21135	COG3008	intermembrane lipid transfer
UNDKW_RS21155	COG1943	Transposase
UNDKW_RS21270	COG0629	single-stranded DNA binding
UNDKW_RS21340	COG0583	DNA-binding transcription factor activity
UNDKW_RS21355	COG0277	FAD linked oxidase domain protein
UNDKW_RS21385	COG0840	transmembrane signaling receptor activity
UNDKW_RS21415	COG0583	DNA-binding transcription factor activity
UNDKW_RS21440	COG1301	dicarboxylic acid transport
UNDKW_RS21455	COG0583	DNA-binding transcription factor activity
UNDKW_RS21585	COG0667	Aldo Keto reductase
UNDKW_RS21590	COG0523	cobalamin synthesis protein
UNDKW_RS21600	COG1136	(ABC) transporter
UNDKW_RS21640	COG0840	transmembrane signaling receptor activity
UNDKW_RS21650	COG2207	Transcriptional regulator
UNDKW_RS21650	COG1917	Cupin 2, conserved barrel domain protein
UNDKW_RS21655	COG0697	spore germination
UNDKW_RS21705	COG0583	DNA-binding transcription factor activity
UNDKW_RS21710	COG2814	Major facilitator Superfamily
UNDKW_RS21790	COG0662	Cupin 2, conserved barrel domain protein
UNDKW_RS21805	COG1802	Transcriptional regulator
UNDKW_RS21815	COG0626	cystathionine gamma-synthase activity
UNDKW_RS21835	COG1073	alpha beta
UNDKW_RS21855	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
UNDKW_RS21880	COG1104	cysteine desulfurase activity
UNDKW_RS21895	COG0583	DNA-binding transcription factor activity
UNDKW_RS21940	COG1028	Short-chain dehydrogenase reductase Sdr
UNDKW_RS21990	COG2982	Protein involved in outer membrane biogenesis
UNDKW_RS22005	COG3218	ABC-type transport auxiliary lipoprotein component
UNDKW_RS22015	COG1127	ABC transporter
UNDKW_RS22020	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
UNDKW_RS22030	COG1295	ribonuclease BN
UNDKW_RS22060	COG0387	Pfam Sodium calcium exchanger
UNDKW_RS22075	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
UNDKW_RS22080	COG0583	DNA-binding transcription factor activity
UNDKW_RS22085	COG1301	dicarboxylic acid transport
UNDKW_RS22110	COG0114	fumarate hydratase activity
UNDKW_RS22220	COG4372	Transposase
UNDKW_RS22270	COG2814	Major facilitator Superfamily
UNDKW_RS22275	COG0583	DNA-binding transcription factor activity
UNDKW_RS22320	COG1770	oligopeptidase
UNDKW_RS22340	COG4677	pectinesterase activity
UNDKW_RS22355	COG3119	arylsulfatase activity
UNDKW_RS22380	COG3719	Belongs to the RNase T2 family
UNDKW_RS22400	COG4191	Histidine kinase
UNDKW_RS22405	COG4566	intracellular signal transduction
UNDKW_RS22415	COG0840	transmembrane signaling receptor activity
UNDKW_RS22420	COG3447	MASE1 domain protein
UNDKW_RS22420	COG5002	protein histidine kinase activity
UNDKW_RS22420	COG5001	Diguanylate cyclase
UNDKW_RS22485	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
UNDKW_RS22490	COG2223	nitrite transmembrane transporter activity
UNDKW_RS22505	COG4771	TonB-dependent receptor
UNDKW_RS22565	COG1846	Transcriptional regulator
UNDKW_RS22610	COG1397	ADP-ribosylglycohydrolase
UNDKW_RS22635	COG1943	Transposase
UNDKW_RS22640	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
UNDKW_RS22640	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
UNDKW_RS22645	COG1611	Belongs to the LOG family
UNDKW_RS22670	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
UNDKW_RS22680	COG0557	exoribonuclease II activity
UNDKW_RS22685	COG3161	chorismate lyase activity
UNDKW_RS22690	COG3150	esterase
UNDKW_RS22695	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
UNDKW_RS22705	COG0501	Belongs to the peptidase M48B family
UNDKW_RS22710	COG4269	membrane
UNDKW_RS22720	COG2264	protein methyltransferase activity
UNDKW_RS22725	COG0439	Biotin carboxylase
UNDKW_RS22730	COG0511	ligase activity, forming carbon-carbon bonds
UNDKW_RS22735	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
UNDKW_RS22740	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
UNDKW_RS22760	COG1566	PFAM secretion protein HlyD family protein
UNDKW_RS22770	COG1846	Transcriptional regulator
UNDKW_RS22790	COG3693	PFAM glycoside hydrolase, family 10
UNDKW_RS22855	COG0642	Histidine kinase
UNDKW_RS22865	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
UNDKW_RS22900	COG2337	Toxic component of a toxin-antitoxin (TA) module
UNDKW_RS22915	COG1846	Transcriptional regulator
UNDKW_RS22920	COG0697	spore germination
UNDKW_RS22925	COG0778	Nitroreductase
UNDKW_RS22940	COG3046	protein related to deoxyribodipyrimidine photolyase
UNDKW_RS22950	COG0288	reversible hydration of carbon dioxide
UNDKW_RS22965	COG3795	YCII-related domain
UNDKW_RS22975	COG0625	glutathione transferase activity
UNDKW_RS22995	COG3842	ATPase activity
UNDKW_RS23000	COG4149	molybdate abc transporter
UNDKW_RS23005	COG0725	ABC transporter, periplasmic molybdate-binding protein
UNDKW_RS23030	COG0484	heat shock protein binding
UNDKW_RS23035	COG0443	Heat shock 70 kDa protein
UNDKW_RS23040	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
UNDKW_RS23060	COG1091	dTDP-4-dehydrorhamnose reductase activity
UNDKW_RS23070	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
UNDKW_RS23095	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
UNDKW_RS23110	COG0859	PFAM glycosyl transferase family 9
UNDKW_RS23140	COG2877	3-deoxy-8-phosphooctulonate synthase activity
UNDKW_RS23160	COG5002	protein histidine kinase activity
UNDKW_RS23160	COG2205	protein histidine kinase activity
UNDKW_RS23160	COG0784	Response regulator, receiver
UNDKW_RS23180	COG0625	glutathione transferase activity
UNDKW_RS23190	COG0411	ABC transporter
UNDKW_RS23250	COG2132	Multicopper oxidase
UNDKW_RS23260	COG2223	nitrite transmembrane transporter activity
UNDKW_RS23265	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
UNDKW_RS23275	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
UNDKW_RS23280	COG2181	nitrate reductase activity
UNDKW_RS23285	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
UNDKW_RS23305	COG0288	reversible hydration of carbon dioxide
UNDKW_RS23310	COG3850	Histidine kinase
UNDKW_RS23315	COG2197	response regulator
UNDKW_RS23320	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
UNDKW_RS23325	COG0826	peptidase U32
UNDKW_RS23330	COG0826	peptidase U32
UNDKW_RS23335	COG3154	lipid carrier protein
UNDKW_RS23355	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
UNDKW_RS23365	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
UNDKW_RS23370	COG0745	RESPONSE REGULATOR receiver
UNDKW_RS23375	COG5002	protein histidine kinase activity
UNDKW_RS23400	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
UNDKW_RS23435	COG3250	beta-galactosidase activity
UNDKW_RS23440	COG5002	protein histidine kinase activity
UNDKW_RS23460	COG0431	NADPH-dependent FMN reductase
UNDKW_RS23500	COG0535	radical SAM domain protein
UNDKW_RS23510	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
UNDKW_RS23540	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
UNDKW_RS23565	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
UNDKW_RS23570	COG0741	lytic transglycosylase activity
UNDKW_RS23580	COG0617	tRNA 3'-terminal CCA addition
UNDKW_RS23590	COG1522	sequence-specific DNA binding
UNDKW_RS23600	COG3186	Phenylalanine-4-hydroxylase
UNDKW_RS23610	COG0745	RESPONSE REGULATOR receiver
UNDKW_RS23630	COG1280	lysine exporter protein (LysE YggA)
UNDKW_RS23640	COG1560	Kdo2-lipid A biosynthetic process
UNDKW_RS23650	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
UNDKW_RS23665	COG0412	Dienelactone hydrolase
UNDKW_RS23700	COG0697	spore germination
UNDKW_RS23725	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
UNDKW_RS23745	COG1722	exodeoxyribonuclease VII activity
UNDKW_RS23750	COG0142	geranyltranstransferase activity
UNDKW_RS23780	COG4689	acetoacetate decarboxylase
UNDKW_RS23785	COG1028	Short-chain dehydrogenase reductase Sdr
UNDKW_RS23800	COG2096	Adenosyltransferase
UNDKW_RS23810	COG0277	FAD linked oxidase domain protein
UNDKW_RS23815	COG0583	DNA-binding transcription factor activity
UNDKW_RS23825	COG4989	oxidoreductase activity
UNDKW_RS23845	COG0739	heme binding
UNDKW_RS23855	COG1490	D-aminoacyl-tRNA deacylase activity
UNDKW_RS23860	COG0406	alpha-ribazole phosphatase activity
UNDKW_RS23870	COG2972	Histidine kinase
UNDKW_RS23885	COG1252	NADH dehydrogenase
UNDKW_RS23890	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
UNDKW_RS23895	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
UNDKW_RS23900	COG0138	bifunctional purine biosynthesis protein purh
UNDKW_RS23905	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
UNDKW_RS23910	COG0632	four-way junction helicase activity
UNDKW_RS23915	COG2255	four-way junction helicase activity
UNDKW_RS23920	COG3971	2-oxopent-4-enoate hydratase activity
UNDKW_RS23945	COG0210	DNA helicase
UNDKW_RS23950	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
UNDKW_RS23965	COG0352	thiamine-phosphate diphosphorylase activity
UNDKW_RS23970	COG0351	phosphomethylpyrimidine kinase
UNDKW_RS23975	COG2022	thiamine diphosphate biosynthetic process
UNDKW_RS23980	COG2104	thiamine diphosphate biosynthetic process
UNDKW_RS23985	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
UNDKW_RS23990	COG3706	GGDEF domain
UNDKW_RS24015	COG0525	valine-tRNA ligase activity
UNDKW_RS24045	COG0418	dihydroorotase activity
UNDKW_RS24065	COG4372	Transposase
UNDKW_RS24075	COG1126	abc transporter atp-binding protein
UNDKW_RS24080	COG0765	amino acid transport
UNDKW_RS24085	COG0765	amino acid transport
UNDKW_RS24095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
UNDKW_RS24100	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
UNDKW_RS24110	COG5265	(ABC) transporter
UNDKW_RS24125	COG1607	acyl-coa hydrolase
UNDKW_RS24130	COG3540	Alkaline phosphatase
UNDKW_RS24135	COG0318	PFAM AMP-dependent synthetase and ligase
UNDKW_RS24140	COG0243	molybdopterin cofactor binding
UNDKW_RS24145	COG2084	Dehydrogenase
UNDKW_RS24150	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
UNDKW_RS24185	COG1024	Enoyl-CoA hydratase
UNDKW_RS24190	COG2967	ApaG domain
UNDKW_RS24195	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
UNDKW_RS24200	COG0546	phosphoglycolate phosphatase activity
UNDKW_RS24215	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
UNDKW_RS24220	COG0134	indole-3-glycerol-phosphate synthase activity
UNDKW_RS24240	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
UNDKW_RS24240	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
UNDKW_RS24245	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
UNDKW_RS24250	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
UNDKW_RS24260	COG0464	growth
UNDKW_RS24275	COG4521	taurine ABC transporter
UNDKW_RS24280	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
UNDKW_RS24285	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
UNDKW_RS24305	COG0584	glycerophosphoryl diester phosphodiesterase
UNDKW_RS24315	COG4185	zeta toxin
UNDKW_RS24325	COG1690	Belongs to the RtcB family
UNDKW_RS24330	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
UNDKW_RS24345	COG0628	permease
UNDKW_RS24370	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
UNDKW_RS24375	COG2011	ABC-type metal ion transport system permease component
UNDKW_RS24380	COG1464	Belongs to the NlpA lipoprotein family
UNDKW_RS24390	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
UNDKW_RS24395	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
UNDKW_RS24400	COG1116	anion transmembrane transporter activity
UNDKW_RS24405	COG0850	regulation of cytokinetic process
UNDKW_RS24410	COG2894	cell division
UNDKW_RS24415	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
UNDKW_RS24420	COG0745	RESPONSE REGULATOR receiver
UNDKW_RS24430	COG2205	protein histidine kinase activity
UNDKW_RS24430	COG2202	Pas domain
UNDKW_RS24435	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
UNDKW_RS24440	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
UNDKW_RS24445	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
UNDKW_RS24450	COG2890	protein-(glutamine-N5) methyltransferase activity
UNDKW_RS24480	COG0529	Catalyzes the synthesis of activated sulfate
UNDKW_RS24515	COG1136	(ABC) transporter
UNDKW_RS24520	COG0577	efflux transmembrane transporter activity
UNDKW_RS24520	COG1136	(ABC) transporter
UNDKW_RS24525	COG0577	efflux transmembrane transporter activity
UNDKW_RS24525	COG1136	(ABC) transporter
UNDKW_RS24535	COG5000	phosphorelay sensor kinase activity
UNDKW_RS24545	COG0745	RESPONSE REGULATOR receiver
UNDKW_RS24555	COG0488	(ABC) transporter
UNDKW_RS24625	COG2183	response to ionizing radiation
UNDKW_RS24630	COG1012	belongs to the aldehyde dehydrogenase family
UNDKW_RS24640	COG3284	Transcriptional regulator
UNDKW_RS24645	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
UNDKW_RS24650	COG0163	prenyltransferase activity
UNDKW_RS24690	COG2969	positive regulation of protein catabolic process
UNDKW_RS24695	COG0625	glutathione transferase activity
UNDKW_RS24700	COG2857	Cytochrome c1
UNDKW_RS24705	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
UNDKW_RS24710	COG0723	plastoquinol--plastocyanin reductase activity
UNDKW_RS24715	COG1970	mechanosensitive ion channel activity
UNDKW_RS24720	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
UNDKW_RS24735	COG0805	protein transport
UNDKW_RS24740	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
UNDKW_RS24745	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
UNDKW_RS24755	COG0140	phosphoribosyl-ATP diphosphatase activity
UNDKW_RS24760	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
UNDKW_RS24765	COG0107	imidazoleglycerol-phosphate synthase activity
UNDKW_RS24770	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
UNDKW_RS24775	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
UNDKW_RS24780	COG0131	Imidazoleglycerol-phosphate dehydratase
UNDKW_RS24785	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
UNDKW_RS24795	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
UNDKW_RS24800	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
UNDKW_RS24805	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
UNDKW_RS24810	COG0271	Belongs to the BolA IbaG family
UNDKW_RS24815	COG0842	Transport permease protein
UNDKW_RS24820	COG1131	(ABC) transporter
UNDKW_RS24840	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
UNDKW_RS24845	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
UNDKW_RS24850	COG1127	ABC transporter
UNDKW_RS24860	COG0067	glutamate synthase
UNDKW_RS24860	COG0069	glutamate synthase activity
UNDKW_RS24860	COG0070	glutamate synthase
UNDKW_RS24875	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
UNDKW_RS24900	COG0513	Belongs to the DEAD box helicase family
UNDKW_RS24915	COG0629	single-stranded DNA binding
UNDKW_RS24920	COG2814	Major facilitator Superfamily
UNDKW_RS24930	COG0193	aminoacyl-tRNA hydrolase activity
UNDKW_RS24960	COG2814	Major facilitator Superfamily
UNDKW_RS24965	COG4533	DNA binding
UNDKW_RS24975	COG0012	GTP binding
UNDKW_RS24985	COG1609	Transcriptional regulator
UNDKW_RS24995	COG4977	sequence-specific DNA binding
UNDKW_RS25010	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
UNDKW_RS25015	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
UNDKW_RS25020	COG0742	ribosomal rna small subunit methyltransferase
UNDKW_RS25030	COG2884	Cell division ATP-binding protein ftsE
UNDKW_RS25040	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
UNDKW_RS25050	COG0109	protoheme IX farnesyltransferase activity
UNDKW_RS25055	COG1612	heme a metabolic process
UNDKW_RS25085	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
UNDKW_RS25090	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
UNDKW_RS25100	COG2226	methyltransferase
UNDKW_RS25115	COG5001	Diguanylate cyclase
UNDKW_RS25115	COG5002	protein histidine kinase activity
UNDKW_RS25115	COG3447	MASE1 domain protein
UNDKW_RS25125	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
UNDKW_RS25135	COG0583	DNA-binding transcription factor activity
UNDKW_RS25140	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
UNDKW_RS25145	COG4208	sulfate ABC transporter
UNDKW_RS25150	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
UNDKW_RS25160	COG3585	molybdate ion transport
UNDKW_RS25165	COG1116	anion transmembrane transporter activity
UNDKW_RS25170	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
UNDKW_RS25175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
UNDKW_RS25180	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
UNDKW_RS25185	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
UNDKW_RS25190	COG0431	NADPH-dependent FMN reductase
UNDKW_RS25195	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
UNDKW_RS25205	COG1414	Transcriptional regulator
UNDKW_RS25230	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
UNDKW_RS25240	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
UNDKW_RS25435	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
UNDKW_RS25575	COG2194	sulfuric ester hydrolase activity
UNDKW_RS25595	COG0446	pyridine nucleotide-disulphide oxidoreductase
UNDKW_RS25595	COG1902	pentaerythritol trinitrate reductase activity
UNDKW_RS25625	COG0683	leucine binding
UNDKW_RS25640	COG2815	serine threonine protein kinase
UNDKW_RS25640	COG0515	serine threonine protein kinase
UNDKW_RS25650	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
UNDKW_RS25675	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
UNDKW_RS25685	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
UNDKW_RS25695	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
UNDKW_RS25700	COG3454	Phosphonate metabolism
UNDKW_RS25705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
UNDKW_RS25710	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
UNDKW_RS25720	COG2910	NAD(P)H-binding
UNDKW_RS25735	COG1073	alpha beta
UNDKW_RS25735	COG2226	methyltransferase
UNDKW_RS25740	COG1032	radical SAM domain protein
UNDKW_RS25745	COG1804	L-carnitine dehydratase bile acid-inducible protein F
UNDKW_RS25755	COG3655	Transcriptional regulator
UNDKW_RS25775	COG0635	Involved in the biosynthesis of porphyrin-containing compound
UNDKW_RS25800	COG1278	Cold shock
UNDKW_RS25830	COG1116	anion transmembrane transporter activity
UNDKW_RS25875	COG1335	isochorismatase
UNDKW_RS25945	COG2363	Small membrane protein
UNDKW_RS25965	COG0840	transmembrane signaling receptor activity
UNDKW_RS25970	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
UNDKW_RS25980	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
UNDKW_RS26000	COG0523	cobalamin synthesis protein
UNDKW_RS26015	COG4206	TonB-dependent receptor
UNDKW_RS26030	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
UNDKW_RS26035	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
UNDKW_RS26045	COG1956	GAF domain-containing protein
UNDKW_RS26055	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
UNDKW_RS26065	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
UNDKW_RS26080	COG0588	phosphoglycerate mutase activity
UNDKW_RS26085	COG4942	peptidase
UNDKW_RS26090	COG0793	Belongs to the peptidase S41A family
UNDKW_RS26095	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
UNDKW_RS26100	COG0625	glutathione transferase activity
UNDKW_RS26105	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
UNDKW_RS26110	COG3552	Protein containing von Willebrand factor type A (VWA) domain
UNDKW_RS26120	COG0714	Associated with various cellular activities
UNDKW_RS26150	COG0411	ABC transporter
UNDKW_RS26165	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
UNDKW_RS26170	COG3447	MASE1 domain protein
UNDKW_RS26170	COG5001	Diguanylate cyclase
UNDKW_RS26170	COG5002	protein histidine kinase activity
UNDKW_RS26195	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
UNDKW_RS26200	COG1595	DNA-templated transcription, initiation
UNDKW_RS26215	COG0302	gtp cyclohydrolase
UNDKW_RS26230	COG1704	LemA family
UNDKW_RS26235	COG2823	Periplasmic or secreted lipoprotein
UNDKW_RS26240	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
UNDKW_RS26245	COG0792	nuclease activity
UNDKW_RS26260	COG0772	Belongs to the SEDS family
UNDKW_RS26265	COG0768	penicillin binding
UNDKW_RS26275	COG1792	Involved in formation and maintenance of cell shape
UNDKW_RS26280	COG1077	Cell shape determining protein MreB Mrl
UNDKW_RS26285	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
UNDKW_RS26290	COG0154	amidase activity
UNDKW_RS26295	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
UNDKW_RS26315	COG0438	transferase activity, transferring glycosyl groups
UNDKW_RS26335	COG2226	methyltransferase
UNDKW_RS26365	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
UNDKW_RS26370	COG1696	Membrane protein involved in D-alanine export
UNDKW_RS26380	COG0438	transferase activity, transferring glycosyl groups
UNDKW_RS26390	COG0662	Cupin 2, conserved barrel domain protein
UNDKW_RS26390	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
UNDKW_RS26410	COG0438	transferase activity, transferring glycosyl groups
UNDKW_RS26420	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
UNDKW_RS26425	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
UNDKW_RS26430	COG0438	transferase activity, transferring glycosyl groups
UNDKW_RS26445	COG0708	Exodeoxyribonuclease III
UNDKW_RS26450	COG0737	Belongs to the 5'-nucleotidase family
UNDKW_RS26470	COG2813	Specifically methylates the guanine in position
UNDKW_RS26470	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
UNDKW_RS26475	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
UNDKW_RS26480	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
UNDKW_RS26495	COG0189	ligase activity
UNDKW_RS26505	COG2329	Antibiotic biosynthesis monooxygenase
UNDKW_RS26515	COG3788	relative of glutathione S-transferase, MAPEG superfamily
UNDKW_RS26525	COG3706	GGDEF domain
UNDKW_RS26610	COG1024	Enoyl-CoA hydratase
UNDKW_RS26710	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
UNDKW_RS26720	COG0577	efflux transmembrane transporter activity
UNDKW_RS26720	COG1136	(ABC) transporter
UNDKW_RS26725	COG1136	(ABC) transporter
UNDKW_RS26725	COG0577	efflux transmembrane transporter activity
UNDKW_RS26730	COG1566	PFAM secretion protein HlyD family protein
UNDKW_RS26740	COG1131	(ABC) transporter
UNDKW_RS26770	COG2918	glutathione biosynthetic process
UNDKW_RS26785	COG1335	isochorismatase
UNDKW_RS26805	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
UNDKW_RS26840	COG1942	4-Oxalocrotonate Tautomerase
UNDKW_RS26850	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
UNDKW_RS26855	COG1262	PFAM Formylglycine-generating sulfatase enzyme
UNDKW_RS26880	COG3852	Histidine kinase
UNDKW_RS26900	COG0643	Histidine kinase
UNDKW_RS26900	COG2198	Histidine kinase
UNDKW_RS26900	COG0784	Response regulator, receiver
UNDKW_RS26905	COG0840	transmembrane signaling receptor activity
UNDKW_RS26910	COG0835	chemotaxis
UNDKW_RS26920	COG0745	RESPONSE REGULATOR receiver
UNDKW_RS26940	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
UNDKW_RS26945	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
UNDKW_RS26950	COG0156	8-amino-7-oxononanoate synthase activity
UNDKW_RS26965	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
UNDKW_RS26975	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
UNDKW_RS26980	COG3012	SEC-C Motif Domain Protein
UNDKW_RS26990	COG1960	acyl-CoA dehydrogenase activity
UNDKW_RS26995	COG1028	Short-chain dehydrogenase reductase Sdr
UNDKW_RS27000	COG0183	Belongs to the thiolase family
UNDKW_RS27005	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
UNDKW_RS27015	COG1960	acyl-CoA dehydrogenase activity
UNDKW_RS27065	COG1595	DNA-templated transcription, initiation
UNDKW_RS27080	COG0366	Alpha amylase catalytic
UNDKW_RS27090	COG0697	spore germination
UNDKW_RS27110	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
UNDKW_RS27115	COG0300	oxidoreductase activity
UNDKW_RS27120	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
UNDKW_RS27130	COG0018	arginyl-trna synthetase
UNDKW_RS27140	COG2974	May be involved in recombination
UNDKW_RS27205	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
UNDKW_RS27205	COG0551	DNA topoisomerase type I activity
UNDKW_RS27210	COG2922	Belongs to the Smg family
UNDKW_RS27215	COG0758	DNA mediated transformation
UNDKW_RS27225	COG0242	peptide deformylase activity
UNDKW_RS27230	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
UNDKW_RS27245	COG0583	DNA-binding transcription factor activity
UNDKW_RS27255	COG0861	Integral membrane protein TerC family
UNDKW_RS27355	COG2059	Chromate
UNDKW_RS27385	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
UNDKW_RS27390	COG1301	dicarboxylic acid transport
UNDKW_RS27400	COG1253	flavin adenine dinucleotide binding
UNDKW_RS27405	COG0443	Heat shock 70 kDa protein
UNDKW_RS27420	COG0745	RESPONSE REGULATOR receiver
UNDKW_RS27440	COG0318	PFAM AMP-dependent synthetase and ligase
UNDKW_RS27470	COG0840	transmembrane signaling receptor activity
UNDKW_RS27490	COG2124	cytochrome p450
UNDKW_RS27505	COG1942	4-Oxalocrotonate Tautomerase
UNDKW_RS27510	COG0402	S-adenosylhomocysteine deaminase activity
UNDKW_RS27520	COG1529	Aldehyde oxidase and xanthine dehydrogenase
UNDKW_RS27570	COG1280	lysine exporter protein (LysE YggA)
UNDKW_RS27590	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
UNDKW_RS27595	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
UNDKW_RS27605	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
UNDKW_RS27615	COG2326	polyphosphate kinase activity
UNDKW_RS27635	COG0355	proton-transporting ATP synthase activity, rotational mechanism
UNDKW_RS27640	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
UNDKW_RS27645	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
UNDKW_RS27650	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
UNDKW_RS27655	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
UNDKW_RS27660	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
UNDKW_RS27670	COG0356	it plays a direct role in the translocation of protons across the membrane
UNDKW_RS27685	COG1475	DNA binding
UNDKW_RS27690	COG1192	Involved in chromosome partitioning
UNDKW_RS27695	COG0357	Ribosomal RNA small subunit methyltransferase G
UNDKW_RS27700	COG0445	tRNA wobble uridine modification
UNDKW_RS27720	COG1454	alcohol dehydrogenase
UNDKW_RS27755	COG1172	Belongs to the binding-protein-dependent transport system permease family
UNDKW_RS27760	COG0559	Belongs to the binding-protein-dependent transport system permease family
UNDKW_RS27775	COG0411	ABC transporter
UNDKW_RS27795	COG0583	DNA-binding transcription factor activity
UNDKW_RS27820	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
UNDKW_RS27850	COG1819	glycosyl
UNDKW_RS27855	COG2814	Major facilitator Superfamily
UNDKW_RS27865	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
UNDKW_RS27865	COG0506	proline dehydrogenase activity
UNDKW_RS27865	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
UNDKW_RS27870	COG1522	sequence-specific DNA binding
UNDKW_RS27875	COG1280	lysine exporter protein (LysE YggA)
UNDKW_RS27890	COG1022	Amp-dependent synthetase and ligase
UNDKW_RS27920	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
UNDKW_RS27930	COG3275	phosphorelay sensor kinase activity
UNDKW_RS27955	COG2972	Histidine kinase
UNDKW_RS27955	COG0745	RESPONSE REGULATOR receiver
UNDKW_RS27960	COG3279	Response regulator of the LytR AlgR family
UNDKW_RS27970	COG4977	sequence-specific DNA binding
UNDKW_RS28010	COG4953	penicillin-binding protein 1C
UNDKW_RS28015	COG2373	Large extracellular alpha-helical protein
UNDKW_RS28040	COG0307	riboflavin synthase, alpha
UNDKW_RS28045	COG2202	Pas domain
UNDKW_RS28045	COG2205	protein histidine kinase activity
UNDKW_RS28070	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
UNDKW_RS28075	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
UNDKW_RS28080	COG3300	MHYT domain
UNDKW_RS28080	COG5001	Diguanylate cyclase
UNDKW_RS28125	COG2375	cellular response to nickel ion
UNDKW_RS28130	COG0583	DNA-binding transcription factor activity
UNDKW_RS28135	COG4948	Mandelate Racemase Muconate Lactonizing
UNDKW_RS28145	COG0436	Aminotransferase
UNDKW_RS28165	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
UNDKW_RS28170	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
UNDKW_RS28175	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
UNDKW_RS28180	COG2205	protein histidine kinase activity
UNDKW_RS28185	COG0745	RESPONSE REGULATOR receiver
UNDKW_RS28210	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
UNDKW_RS28220	COG0784	Response regulator, receiver
UNDKW_RS28220	COG2205	protein histidine kinase activity
UNDKW_RS28225	COG3842	ATPase activity
UNDKW_RS28255	COG0642	Histidine kinase
UNDKW_RS28320	COG2900	Belongs to the SlyX family
UNDKW_RS28330	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
UNDKW_RS28340	COG0583	DNA-binding transcription factor activity
UNDKW_RS28345	COG2351	hydroxyisourate hydrolase activity
UNDKW_RS28360	COG2233	PERMEase
UNDKW_RS28405	COG2972	Histidine kinase
UNDKW_RS28415	COG3291	Pkd domain containing protein
UNDKW_RS28425	COG0469	pyruvate kinase activity
UNDKW_RS28435	COG2084	Dehydrogenase
UNDKW_RS28440	COG3622	Belongs to the hyi family
UNDKW_RS28445	COG3960	tartronate-semialdehyde synthase activity
UNDKW_RS28450	COG0583	DNA-binding transcription factor activity
UNDKW_RS28455	COG2252	PERMEase
UNDKW_RS28475	COG0583	DNA-binding transcription factor activity
UNDKW_RS28490	COG2162	N-hydroxyarylamine O-acetyltransferase activity
UNDKW_RS28500	COG0513	Belongs to the DEAD box helicase family
UNDKW_RS28520	COG2207	Transcriptional regulator
UNDKW_RS28535	COG4990	cell redox homeostasis
UNDKW_RS28535	COG3591	Belongs to the peptidase S1B family
UNDKW_RS28570	COG0784	Response regulator, receiver
UNDKW_RS28575	COG2205	protein histidine kinase activity
UNDKW_RS28575	COG2202	Pas domain
UNDKW_RS28585	COG3437	response regulator, receiver
UNDKW_RS28610	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
UNDKW_RS28640	COG0612	Peptidase, M16
UNDKW_RS28655	COG0154	amidase activity
UNDKW_RS28670	COG5002	protein histidine kinase activity
UNDKW_RS28680	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
UNDKW_RS28690	COG0612	Peptidase, M16
UNDKW_RS28705	COG4206	TonB-dependent receptor
UNDKW_RS28715	COG4771	TonB-dependent receptor
UNDKW_RS28720	COG0840	transmembrane signaling receptor activity
UNDKW_RS28730	COG2223	nitrite transmembrane transporter activity
UNDKW_RS28735	COG2207	Transcriptional regulator
UNDKW_RS28740	COG0339	signal peptide processing
UNDKW_RS28745	COG2271	Major facilitator Superfamily
UNDKW_RS28760	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
UNDKW_RS28775	COG3119	arylsulfatase activity
UNDKW_RS28785	COG0183	Belongs to the thiolase family
UNDKW_RS28795	COG1506	peptidase
UNDKW_RS28835	COG3104	oligopeptide transport
UNDKW_RS28850	COG0840	transmembrane signaling receptor activity
UNDKW_RS28870	COG0745	RESPONSE REGULATOR receiver
UNDKW_RS28875	COG2972	Histidine kinase
UNDKW_RS28885	COG0084	hydrolase, TatD family'
UNDKW_RS28930	COG0747	negative chemotaxis
UNDKW_RS28945	COG1028	Short-chain dehydrogenase reductase Sdr
UNDKW_RS28970	COG0583	DNA-binding transcription factor activity
UNDKW_RS28985	COG0667	Aldo Keto reductase
UNDKW_RS29005	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
UNDKW_RS29025	COG2902	Dehydrogenase
UNDKW_RS29040	COG3590	peptidase
UNDKW_RS29045	COG3279	Response regulator of the LytR AlgR family
UNDKW_RS29060	COG1529	Aldehyde oxidase and xanthine dehydrogenase
UNDKW_RS29060	COG2010	Cytochrome c
UNDKW_RS29085	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
UNDKW_RS29100	COG3275	phosphorelay sensor kinase activity
UNDKW_RS29105	COG3279	Response regulator of the LytR AlgR family
UNDKW_RS29110	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
UNDKW_RS29120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
UNDKW_RS29125	COG3541	Predicted nucleotidyltransferase
UNDKW_RS29260	COG3132	Protein of unknown function, DUF480
UNDKW_RS29275	COG4260	virion core protein, lumpy skin disease virus
UNDKW_RS29330	COG1902	pentaerythritol trinitrate reductase activity
UNDKW_RS29335	COG1309	transcriptional regulator
UNDKW_RS29340	COG0527	aspartate kinase activity
UNDKW_RS29340	COG0460	homoserine dehydrogenase
UNDKW_RS29355	COG0515	serine threonine protein kinase
UNDKW_RS29365	COG1846	Transcriptional regulator
UNDKW_RS29380	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
UNDKW_RS29410	COG0415	Belongs to the DNA photolyase family
UNDKW_RS29415	COG0415	Belongs to the DNA photolyase family
UNDKW_RS29435	COG0840	transmembrane signaling receptor activity
UNDKW_RS29440	COG0840	transmembrane signaling receptor activity
UNDKW_RS29465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
UNDKW_RS29465	COG4191	Histidine kinase
UNDKW_RS29520	COG0121	glutamine amidotransferase
UNDKW_RS29540	COG2124	cytochrome p450
UNDKW_RS29555	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
UNDKW_RS29560	COG0706	membrane insertase activity
UNDKW_RS29565	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
UNDKW_RS29570	COG0594	ribonuclease P activity
UNDKW_RS29575	COG0230	Belongs to the bacterial ribosomal protein bL34 family
UNDKW_RS29600	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
UNDKW_RS29610	COG4771	TonB-dependent receptor
UNDKW_RS29685	COG1475	DNA binding
UNDKW_RS29695	COG4974	Belongs to the 'phage' integrase family
UNDKW_RS29700	COG3550	peptidyl-serine autophosphorylation
UNDKW_RS29945	COG0464	growth