locus-tag	class	description
LPB138_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LPB138_RS00010	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LPB138_RS00025	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LPB138_RS00035	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LPB138_RS00040	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LPB138_RS00055	COG4628	conserved protein (DUF2132)
LPB138_RS00095	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LPB138_RS00125	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LPB138_RS00150	COG0497	DNA recombination
LPB138_RS00155	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
LPB138_RS00175	COG0706	membrane insertase activity
LPB138_RS00180	COG0504	CTP synthase activity
LPB138_RS00185	COG0513	Belongs to the DEAD box helicase family
LPB138_RS00195	COG1028	Short-chain dehydrogenase reductase Sdr
LPB138_RS00200	COG0230	Belongs to the bacterial ribosomal protein bL34 family
LPB138_RS00205	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LPB138_RS00220	COG1562	ergosterol biosynthetic process
LPB138_RS00240	COG0415	Belongs to the DNA photolyase family
LPB138_RS00280	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LPB138_RS00310	COG3956	TIGRFAM MazG family protein
LPB138_RS00320	COG0242	peptide deformylase activity
LPB138_RS00335	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LPB138_RS00340	COG2171	N-acyltransferase activity
LPB138_RS00360	COG1132	(ABC) transporter
LPB138_RS00365	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LPB138_RS00370	COG0463	Glycosyl transferase, family 2
LPB138_RS00385	COG0300	oxidoreductase activity
LPB138_RS00390	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LPB138_RS00400	COG0556	nucleotide-excision repair
LPB138_RS00410	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LPB138_RS00430	COG3291	Pkd domain containing protein
LPB138_RS00445	COG1131	(ABC) transporter
LPB138_RS00475	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
LPB138_RS00480	COG2996	Protein conserved in bacteria
LPB138_RS00500	COG0788	formyltetrahydrofolate deformylase activity
LPB138_RS00510	COG0668	transmembrane transport
LPB138_RS00525	COG1546	Belongs to the CinA family
LPB138_RS00525	COG1058	Belongs to the CinA family
LPB138_RS00530	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LPB138_RS00535	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LPB138_RS00545	COG0552	protein localization to endoplasmic reticulum
LPB138_RS00550	COG0657	acetylesterase activity
LPB138_RS00550	COG2755	lipolytic protein G-D-S-L family
LPB138_RS00575	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LPB138_RS00610	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
LPB138_RS00615	COG1363	Peptidase, m42
LPB138_RS00660	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
LPB138_RS00665	COG0602	queuosine metabolic process
LPB138_RS00670	COG0433	COG0433 Predicted ATPase
LPB138_RS00700	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LPB138_RS00705	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LPB138_RS00710	COG0513	Belongs to the DEAD box helicase family
LPB138_RS00715	COG2201	protein-glutamate methylesterase activity
LPB138_RS00720	COG4251	negative regulation of phosphorylation
LPB138_RS00730	COG0488	(ABC) transporter
LPB138_RS00755	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LPB138_RS00755	COG0321	lipoyl(octanoyl) transferase activity
LPB138_RS00800	COG0668	transmembrane transport
LPB138_RS00805	COG0783	Belongs to the Dps family
LPB138_RS00815	COG0071	Belongs to the small heat shock protein (HSP20) family
LPB138_RS00855	COG3177	Filamentation induced by cAMP protein fic
LPB138_RS00975	COG4680	protein conserved in bacteria
LPB138_RS01005	COG4680	protein conserved in bacteria
LPB138_RS01095	COG0545	Peptidyl-prolyl cis-trans isomerase
LPB138_RS01145	COG3609	addiction module antidote protein, CC2985 family
LPB138_RS01255	COG4974	Belongs to the 'phage' integrase family
LPB138_RS01315	COG0045	succinate-CoA ligase (ADP-forming) activity
LPB138_RS01330	COG1132	(ABC) transporter
LPB138_RS01335	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LPB138_RS01345	COG1862	Preprotein translocase
LPB138_RS01355	COG0237	dephospho-CoA kinase activity
LPB138_RS01370	COG0009	L-threonylcarbamoyladenylate synthase
LPB138_RS01380	COG1278	Cold shock
LPB138_RS01395	COG2234	aminopeptidase activity
LPB138_RS01405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LPB138_RS01410	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LPB138_RS01415	COG1522	sequence-specific DNA binding
LPB138_RS01420	COG0626	cystathionine gamma-synthase activity
LPB138_RS01425	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LPB138_RS01445	COG1295	ribonuclease BN
LPB138_RS01450	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
LPB138_RS01460	COG0124	histidyl-tRNA synthetase
LPB138_RS01465	COG0302	gtp cyclohydrolase
LPB138_RS01495	COG0714	Associated with various cellular activities
LPB138_RS01500	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
LPB138_RS01510	COG0653	protein targeting
LPB138_RS01520	COG2096	Adenosyltransferase
LPB138_RS01545	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LPB138_RS01560	COG1393	Belongs to the ArsC family
LPB138_RS01575	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LPB138_RS01585	COG2234	aminopeptidase activity
LPB138_RS01590	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LPB138_RS01610	COG1301	dicarboxylic acid transport
LPB138_RS01620	COG0189	ligase activity
LPB138_RS01625	COG2897	thiosulfate sulfurtransferase activity
LPB138_RS01645	COG3011	Protein conserved in bacteria
LPB138_RS01650	COG1136	(ABC) transporter
LPB138_RS01655	COG1136	(ABC) transporter
LPB138_RS01655	COG0577	efflux transmembrane transporter activity
LPB138_RS01660	COG0577	efflux transmembrane transporter activity
LPB138_RS01660	COG1136	(ABC) transporter
LPB138_RS01665	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LPB138_RS01670	COG1250	3-hydroxyacyl-CoA dehydrogenase
LPB138_RS01680	COG0673	inositol 2-dehydrogenase activity
LPB138_RS01685	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LPB138_RS01695	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
LPB138_RS01705	COG0386	Belongs to the glutathione peroxidase family
LPB138_RS01715	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LPB138_RS01725	COG1012	belongs to the aldehyde dehydrogenase family
LPB138_RS01735	COG3250	beta-galactosidase activity
LPB138_RS01740	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LPB138_RS01745	COG1595	DNA-templated transcription, initiation
LPB138_RS01750	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LPB138_RS01755	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LPB138_RS01765	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LPB138_RS01800	COG1418	mRNA catabolic process
LPB138_RS01805	COG4974	Belongs to the 'phage' integrase family
LPB138_RS01810	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
LPB138_RS01825	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LPB138_RS01855	COG0463	Glycosyl transferase, family 2
LPB138_RS01860	COG1215	transferase activity, transferring glycosyl groups
LPB138_RS01875	COG1216	Glycosyl transferase, family 2
LPB138_RS01905	COG0463	Glycosyl transferase, family 2
LPB138_RS01905	COG1216	Glycosyl transferase, family 2
LPB138_RS01915	COG2089	acid synthase
LPB138_RS01920	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LPB138_RS01925	COG1083	cytidylyl-transferase
LPB138_RS01930	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LPB138_RS01975	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LPB138_RS01990	COG0429	hydrolase of the alpha beta-hydrolase fold
LPB138_RS01995	COG1183	phosphatidylcholine synthase activity
LPB138_RS02000	COG1137	ATPase activity
LPB138_RS02010	COG0805	protein transport
LPB138_RS02015	COG0517	IMP dehydrogenase activity
LPB138_RS02015	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LPB138_RS02020	COG0514	ATP-dependent DNA helicase (RecQ)
LPB138_RS02040	COG2197	response regulator
LPB138_RS02045	COG2197	response regulator
LPB138_RS02075	COG0116	Belongs to the methyltransferase superfamily
LPB138_RS02090	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LPB138_RS02100	COG0740	serine-type endopeptidase activity
LPB138_RS02140	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LPB138_RS02150	COG0776	regulation of translation
LPB138_RS02155	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LPB138_RS02160	COG0514	ATP-dependent DNA helicase (RecQ)
LPB138_RS02175	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LPB138_RS02185	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LPB138_RS02190	COG0714	Associated with various cellular activities
LPB138_RS02210	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LPB138_RS02230	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LPB138_RS02235	COG1770	oligopeptidase
LPB138_RS02255	COG2326	polyphosphate kinase activity
LPB138_RS02295	COG2972	Histidine kinase
LPB138_RS02295	COG0745	RESPONSE REGULATOR receiver
LPB138_RS02300	COG3279	Response regulator of the LytR AlgR family
LPB138_RS02315	COG1621	beta-fructofuranosidase activity
LPB138_RS02335	COG0579	oxidoreductase
LPB138_RS02340	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
LPB138_RS02370	COG2223	nitrite transmembrane transporter activity
LPB138_RS02375	COG3012	SEC-C Motif Domain Protein
LPB138_RS02405	COG3421	Type III restriction
LPB138_RS02415	COG2189	Belongs to the N(4) N(6)-methyltransferase family
LPB138_RS02445	COG4974	Belongs to the 'phage' integrase family
LPB138_RS02455	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LPB138_RS02480	COG0659	secondary active sulfate transmembrane transporter activity
LPB138_RS02490	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LPB138_RS02510	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LPB138_RS02510	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LPB138_RS02515	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LPB138_RS02520	COG1086	Polysaccharide biosynthesis protein
LPB138_RS02530	COG0167	dihydroorotate dehydrogenase activity
LPB138_RS02560	COG0823	Involved in the tonB-independent uptake of proteins
LPB138_RS02570	COG3386	PFAM SMP-30 Gluconolaconase
LPB138_RS02575	COG0360	Binds together with S18 to 16S ribosomal RNA
LPB138_RS02580	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LPB138_RS02585	COG0359	binds to the 23S rRNA
LPB138_RS02615	COG0686	Belongs to the AlaDH PNT family
LPB138_RS02620	COG0802	atpase or kinase
LPB138_RS02625	COG2204	response regulator
LPB138_RS02630	COG1078	dGTPase activity
LPB138_RS02635	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LPB138_RS02640	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
LPB138_RS02640	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LPB138_RS02645	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LPB138_RS02650	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LPB138_RS02655	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LPB138_RS02665	COG0612	Peptidase, M16
LPB138_RS02670	COG0737	Belongs to the 5'-nucleotidase family
LPB138_RS02695	COG0516	GMP reductase activity
LPB138_RS02695	COG0517	IMP dehydrogenase activity
LPB138_RS02705	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LPB138_RS02730	COG1528	Iron-storage protein
LPB138_RS02745	COG3275	phosphorelay sensor kinase activity
LPB138_RS02765	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LPB138_RS02770	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LPB138_RS02785	COG2176	DNA-directed DNA polymerase activity
LPB138_RS02790	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LPB138_RS02800	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LPB138_RS02805	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LPB138_RS02815	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LPB138_RS02820	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
LPB138_RS02830	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LPB138_RS02840	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LPB138_RS02845	COG0012	GTP binding
LPB138_RS02870	COG1794	racemase activity, acting on amino acids and derivatives
LPB138_RS02875	COG0668	transmembrane transport
LPB138_RS02890	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
LPB138_RS02900	COG0516	GMP reductase activity
LPB138_RS02905	COG4771	TonB-dependent receptor
LPB138_RS02920	COG0210	DNA helicase
LPB138_RS02930	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LPB138_RS02935	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LPB138_RS02940	COG0484	heat shock protein binding
LPB138_RS02950	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LPB138_RS02970	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LPB138_RS02980	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LPB138_RS02990	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LPB138_RS02995	COG0501	Belongs to the peptidase M48B family
LPB138_RS03000	COG0791	NLP P60 protein
LPB138_RS03005	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LPB138_RS03015	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LPB138_RS03025	COG0305	Participates in initiation and elongation during chromosome replication
LPB138_RS03035	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LPB138_RS03040	COG0438	transferase activity, transferring glycosyl groups
LPB138_RS03045	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LPB138_RS03100	COG3265	gluconokinase activity
LPB138_RS03120	COG2211	Major facilitator Superfamily
LPB138_RS03140	COG2814	Major facilitator Superfamily
LPB138_RS03165	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LPB138_RS03170	COG0066	3-isopropylmalate dehydratase activity
LPB138_RS03175	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LPB138_RS03180	COG0473	3-isopropylmalate dehydrogenase activity
LPB138_RS03200	COG1609	Transcriptional regulator
LPB138_RS03225	COG0326	Molecular chaperone. Has ATPase activity
LPB138_RS03240	COG1309	transcriptional regulator
LPB138_RS03255	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LPB138_RS03260	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LPB138_RS03275	COG0352	thiamine-phosphate diphosphorylase activity
LPB138_RS03300	COG1278	Cold shock
LPB138_RS03305	COG1064	alcohol dehydrogenase
LPB138_RS03310	COG1764	response to oxidative stress
LPB138_RS03320	COG1902	pentaerythritol trinitrate reductase activity
LPB138_RS03340	COG2307	Protein conserved in bacteria
LPB138_RS03340	COG2308	Evidence 4 Homologs of previously reported genes of
LPB138_RS03355	COG2308	Evidence 4 Homologs of previously reported genes of
LPB138_RS03360	COG1278	Cold shock
LPB138_RS03390	COG0513	Belongs to the DEAD box helicase family
LPB138_RS03410	COG3279	Response regulator of the LytR AlgR family
LPB138_RS03420	COG2205	protein histidine kinase activity
LPB138_RS03420	COG0784	Response regulator, receiver
LPB138_RS03425	COG0300	oxidoreductase activity
LPB138_RS03450	COG1733	regulation of RNA biosynthetic process
LPB138_RS03500	COG1228	amidohydrolase
LPB138_RS03505	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LPB138_RS03510	COG2986	histidine ammonia-lyase
LPB138_RS03560	COG1187	pseudouridine synthase activity
LPB138_RS03575	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
LPB138_RS03605	COG4206	TonB-dependent receptor
LPB138_RS03655	COG0022	dehydrogenase e1 component
LPB138_RS03660	COG1522	sequence-specific DNA binding
LPB138_RS03695	COG1595	DNA-templated transcription, initiation
LPB138_RS03715	COG2195	Cleaves the N-terminal amino acid of tripeptides
LPB138_RS03720	COG0019	diaminopimelate decarboxylase activity
LPB138_RS03725	COG0460	homoserine dehydrogenase
LPB138_RS03725	COG0527	aspartate kinase activity
LPB138_RS03730	COG0083	homoserine kinase activity
LPB138_RS03735	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LPB138_RS03740	COG0857	belongs to the CobB CobQ family
LPB138_RS03740	COG0280	phosphate acetyltransferase
LPB138_RS03745	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LPB138_RS03755	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LPB138_RS03755	COG3153	acetyltransferase
LPB138_RS03760	COG0006	proline dipeptidase activity
LPB138_RS03765	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LPB138_RS03785	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LPB138_RS03800	COG0542	response to heat
LPB138_RS03820	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LPB138_RS03830	COG0424	maF-like protein
LPB138_RS03835	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LPB138_RS03850	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LPB138_RS03855	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LPB138_RS03860	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LPB138_RS03905	COG1028	Short-chain dehydrogenase reductase Sdr
LPB138_RS03910	COG4191	Histidine kinase
LPB138_RS03925	COG1136	(ABC) transporter
LPB138_RS03930	COG0577	efflux transmembrane transporter activity
LPB138_RS03930	COG1136	(ABC) transporter
LPB138_RS03935	COG0577	efflux transmembrane transporter activity
LPB138_RS03940	COG1136	(ABC) transporter
LPB138_RS03985	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LPB138_RS03990	COG0539	negative regulation of cytoplasmic translation
LPB138_RS03995	COG3279	Response regulator of the LytR AlgR family
LPB138_RS04010	COG3275	phosphorelay sensor kinase activity
LPB138_RS04040	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LPB138_RS04050	COG2318	DinB family
LPB138_RS04075	COG2885	chlorophyll binding
LPB138_RS04080	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LPB138_RS04090	COG0247	lactate metabolic process
LPB138_RS04090	COG0277	FAD linked oxidase domain protein
LPB138_RS04100	COG0531	amino acid
LPB138_RS04130	COG0783	Belongs to the Dps family
LPB138_RS04160	COG1482	cell wall glycoprotein biosynthetic process
LPB138_RS04165	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LPB138_RS04175	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
LPB138_RS04190	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LPB138_RS04210	COG1278	Cold shock
LPB138_RS04215	COG1278	Cold shock
LPB138_RS04220	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LPB138_RS04225	COG1193	negative regulation of DNA recombination
LPB138_RS04230	COG1360	Flagellar Motor Protein
LPB138_RS04235	COG3743	rRNA binding
LPB138_RS04235	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LPB138_RS04245	COG0534	Mate efflux family protein
LPB138_RS04250	COG0450	alkyl hydroperoxide reductase
LPB138_RS04255	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LPB138_RS04270	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
LPB138_RS04275	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LPB138_RS04285	COG1674	ftsk spoiiie
LPB138_RS04300	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LPB138_RS04300	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LPB138_RS04310	COG3340	Belongs to the peptidase S51 family
LPB138_RS04320	COG4206	TonB-dependent receptor
LPB138_RS04320	COG1629	transport
LPB138_RS04325	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LPB138_RS04330	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
LPB138_RS04340	COG0215	cysteine-tRNA ligase activity
LPB138_RS04350	COG0463	Glycosyl transferase, family 2
LPB138_RS04375	COG0671	phosphoesterase, PA-phosphatase related
LPB138_RS04380	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LPB138_RS04395	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LPB138_RS04400	COG0105	UTP biosynthetic process
LPB138_RS04420	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LPB138_RS04430	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LPB138_RS04440	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LPB138_RS04470	COG0747	negative chemotaxis
LPB138_RS04480	COG2329	Antibiotic biosynthesis monooxygenase
LPB138_RS04490	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LPB138_RS04505	COG0741	lytic transglycosylase activity
LPB138_RS04505	COG1388	LysM domain
LPB138_RS04510	COG0730	response to heat
LPB138_RS04525	COG0482	sulfurtransferase activity
LPB138_RS04530	COG3525	Glycosyl hydrolase, family 20, catalytic domain
LPB138_RS04550	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
LPB138_RS04580	COG1253	flavin adenine dinucleotide binding
LPB138_RS04590	COG4771	TonB-dependent receptor
LPB138_RS04595	COG0432	Pfam Uncharacterised protein family UPF0047
LPB138_RS04600	COG0579	oxidoreductase
LPB138_RS04605	COG2270	Major facilitator Superfamily
LPB138_RS04630	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LPB138_RS04645	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LPB138_RS04675	COG0813	purine-nucleoside phosphorylase activity
LPB138_RS04685	COG0589	response to stress
LPB138_RS04690	COG0525	valine-tRNA ligase activity
LPB138_RS04705	COG0436	Aminotransferase
LPB138_RS04710	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LPB138_RS04725	COG1216	Glycosyl transferase, family 2
LPB138_RS04740	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LPB138_RS04750	COG3876	Protein conserved in bacteria
LPB138_RS04775	COG0018	arginyl-trna synthetase
LPB138_RS04785	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LPB138_RS04790	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
LPB138_RS04815	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LPB138_RS04830	COG0561	phosphatase activity
LPB138_RS04835	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
LPB138_RS04845	COG1696	Membrane protein involved in D-alanine export
LPB138_RS04850	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LPB138_RS04855	COG1702	phosphate starvation-inducible protein PhoH
LPB138_RS04900	COG0592	DNA-directed DNA polymerase activity
LPB138_RS04910	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
LPB138_RS04915	COG0405	Gamma-glutamyltransferase
LPB138_RS04935	COG0628	permease
LPB138_RS04950	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LPB138_RS04975	COG1480	7TM receptor with intracellular HD hydrolase
LPB138_RS04980	COG0183	Belongs to the thiolase family
LPB138_RS04985	COG0791	NLP P60 protein
LPB138_RS05000	COG0542	response to heat
LPB138_RS05020	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LPB138_RS05025	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LPB138_RS05030	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LPB138_RS05035	COG0825	malonyl-CoA metabolic process
LPB138_RS05050	COG0343	queuine tRNA-ribosyltransferase activity
LPB138_RS05075	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LPB138_RS05085	COG4733	cellulase activity
LPB138_RS05085	COG5297	Belongs to the glycosyl hydrolase family 6
LPB138_RS05110	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LPB138_RS05130	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LPB138_RS05145	COG1216	Glycosyl transferase, family 2
LPB138_RS05150	COG0438	transferase activity, transferring glycosyl groups
LPB138_RS05160	COG1216	Glycosyl transferase, family 2
LPB138_RS05160	COG1442	glycosyl transferase family 8
LPB138_RS05165	COG5039	Polysaccharide pyruvyl transferase
LPB138_RS05180	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LPB138_RS05180	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LPB138_RS05185	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LPB138_RS05185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LPB138_RS05190	COG0730	response to heat
LPB138_RS05260	COG2207	Transcriptional regulator
LPB138_RS05265	COG1294	oxidase, subunit
LPB138_RS05270	COG1271	oxidase subunit
LPB138_RS05290	COG3250	beta-galactosidase activity
LPB138_RS05295	COG3867	Arabinogalactan endo-beta-1,4-galactanase
LPB138_RS05305	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
LPB138_RS05310	COG1629	transport
LPB138_RS05310	COG4206	TonB-dependent receptor
LPB138_RS05325	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LPB138_RS05350	COG4206	TonB-dependent receptor
LPB138_RS05350	COG1629	transport
LPB138_RS05360	COG0745	RESPONSE REGULATOR receiver
LPB138_RS05360	COG2205	protein histidine kinase activity
LPB138_RS05360	COG4191	Histidine kinase
LPB138_RS05365	COG0702	epimerase
LPB138_RS05375	COG1733	regulation of RNA biosynthetic process
LPB138_RS05450	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LPB138_RS05460	COG2217	Heavy metal translocating P-type atpase
LPB138_RS05475	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LPB138_RS05485	COG2217	Heavy metal translocating P-type atpase
LPB138_RS05520	COG4974	Belongs to the 'phage' integrase family
LPB138_RS05530	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LPB138_RS05535	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LPB138_RS05615	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LPB138_RS05620	COG0085	RNA polymerase activity
LPB138_RS05625	COG0222	ribosome binding
LPB138_RS05630	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LPB138_RS05635	COG0081	regulation of translation
LPB138_RS05640	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LPB138_RS05695	COG4974	Belongs to the 'phage' integrase family
LPB138_RS05700	COG0828	Belongs to the bacterial ribosomal protein bS21 family
LPB138_RS05705	COG1960	acyl-CoA dehydrogenase activity
LPB138_RS05715	COG1115	amino acid carrier protein
LPB138_RS05720	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LPB138_RS05735	COG1611	Belongs to the LOG family
LPB138_RS05765	COG0778	Nitroreductase
LPB138_RS05770	COG2195	Cleaves the N-terminal amino acid of tripeptides
LPB138_RS05775	COG1090	epimerase
LPB138_RS05780	COG1192	Involved in chromosome partitioning
LPB138_RS05785	COG1475	DNA binding
LPB138_RS05795	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LPB138_RS05800	COG0681	Belongs to the peptidase S26 family
LPB138_RS05825	COG0488	(ABC) transporter
LPB138_RS05830	COG1741	Belongs to the pirin family
LPB138_RS05835	COG1846	Transcriptional regulator
LPB138_RS05840	COG0431	NADPH-dependent FMN reductase
LPB138_RS05845	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LPB138_RS05860	COG0217	transcriptional regulatory protein
LPB138_RS05870	COG2304	oxidoreductase activity
LPB138_RS05890	COG1266	CAAX protease self-immunity
LPB138_RS05895	COG4948	Mandelate Racemase Muconate Lactonizing
LPB138_RS05915	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
LPB138_RS05930	COG1575	Belongs to the MenA family. Type 1 subfamily
LPB138_RS05940	COG2181	nitrate reductase activity
LPB138_RS05940	COG0247	lactate metabolic process
LPB138_RS05950	COG2181	nitrate reductase activity
LPB138_RS05950	COG0247	lactate metabolic process
LPB138_RS05955	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LPB138_RS05960	COG0860	N-Acetylmuramoyl-L-alanine amidase
LPB138_RS05970	COG0251	oxidation-reduction process
LPB138_RS05975	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LPB138_RS05985	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LPB138_RS06000	COG1595	DNA-templated transcription, initiation
LPB138_RS06005	COG0508	dehydrogenase complex catalyzes the overall conversion of
LPB138_RS06015	COG0408	coproporphyrinogen oxidase activity
LPB138_RS06020	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LPB138_RS06025	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LPB138_RS06035	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LPB138_RS06040	COG0113	porphobilinogen synthase activity
LPB138_RS06045	COG0181	hydroxymethylbilane synthase activity
LPB138_RS06050	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LPB138_RS06060	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LPB138_RS06075	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LPB138_RS06085	COG0259	pyridoxamine-phosphate oxidase activity
LPB138_RS06100	COG2885	chlorophyll binding
LPB138_RS06100	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
LPB138_RS06110	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LPB138_RS06115	COG1663	tetraacyldisaccharide 4'-kinase activity
LPB138_RS06120	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LPB138_RS06135	COG0662	Cupin 2, conserved barrel domain protein
LPB138_RS06145	COG3844	kynureninase activity
LPB138_RS06155	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LPB138_RS06155	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LPB138_RS06160	COG0494	nUDIX hydrolase
LPB138_RS06165	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LPB138_RS06205	COG0254	rRNA binding
LPB138_RS06220	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LPB138_RS06225	COG1028	Short-chain dehydrogenase reductase Sdr
LPB138_RS06230	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LPB138_RS06250	COG4771	TonB-dependent receptor
LPB138_RS06255	COG2133	pyrroloquinoline quinone binding
LPB138_RS06265	COG1127	ABC transporter
LPB138_RS06270	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LPB138_RS06285	COG2226	methyltransferase
LPB138_RS06290	COG0295	cytidine deaminase activity
LPB138_RS06305	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LPB138_RS06310	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LPB138_RS06325	COG0205	6-phosphofructokinase activity
LPB138_RS06330	COG0366	Alpha amylase catalytic
LPB138_RS06340	COG0366	Alpha amylase catalytic
LPB138_RS06345	COG1554	hydrolase, family 65, central catalytic
LPB138_RS06350	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LPB138_RS06355	COG2211	Major facilitator Superfamily
LPB138_RS06360	COG1609	Transcriptional regulator
LPB138_RS06365	COG1629	transport
LPB138_RS06365	COG4206	TonB-dependent receptor
LPB138_RS06370	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
LPB138_RS06440	COG0285	dihydrofolate synthase activity
LPB138_RS06450	COG0848	biopolymer transport protein
LPB138_RS06455	COG0811	peptide transport
LPB138_RS06460	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LPB138_RS06465	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
LPB138_RS06470	COG1960	acyl-CoA dehydrogenase activity
LPB138_RS06480	COG0347	Belongs to the P(II) protein family
LPB138_RS06485	COG0004	ammonium transporteR
LPB138_RS06490	COG0067	glutamate synthase
LPB138_RS06490	COG0070	glutamate synthase
LPB138_RS06490	COG0069	glutamate synthase activity
LPB138_RS06535	COG0243	molybdopterin cofactor binding
LPB138_RS06540	COG2197	response regulator
LPB138_RS06550	COG1116	anion transmembrane transporter activity
LPB138_RS06555	COG1116	anion transmembrane transporter activity
LPB138_RS06560	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LPB138_RS06575	COG2223	nitrite transmembrane transporter activity
LPB138_RS06585	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LPB138_RS06605	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LPB138_RS06610	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LPB138_RS06615	COG0291	Belongs to the bacterial ribosomal protein bL35 family
LPB138_RS06620	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LPB138_RS06625	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
LPB138_RS06630	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LPB138_RS06635	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LPB138_RS06645	COG0174	glutamine synthetase
LPB138_RS06675	COG0702	epimerase
LPB138_RS06700	COG0302	gtp cyclohydrolase
LPB138_RS06705	COG1028	Short-chain dehydrogenase reductase Sdr
LPB138_RS06710	COG0386	Belongs to the glutathione peroxidase family
LPB138_RS06735	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LPB138_RS06740	COG2264	protein methyltransferase activity
LPB138_RS06745	COG0149	triose-phosphate isomerase activity
LPB138_RS06755	COG0284	orotidine-5'-phosphate decarboxylase activity
LPB138_RS06780	COG1595	DNA-templated transcription, initiation
LPB138_RS06810	COG1611	Belongs to the LOG family
LPB138_RS06815	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LPB138_RS06820	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LPB138_RS06825	COG1132	(ABC) transporter
LPB138_RS06830	COG0101	tRNA pseudouridine synthase activity
LPB138_RS06840	COG4585	Histidine kinase
LPB138_RS06845	COG4585	Histidine kinase
LPB138_RS06880	COG1253	flavin adenine dinucleotide binding
LPB138_RS06905	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
LPB138_RS06915	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LPB138_RS06935	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LPB138_RS06935	COG0140	phosphoribosyl-ATP diphosphatase activity
LPB138_RS06940	COG0107	imidazoleglycerol-phosphate synthase activity
LPB138_RS06945	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LPB138_RS06955	COG0131	Imidazoleglycerol-phosphate dehydratase
LPB138_RS06960	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LPB138_RS06965	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LPB138_RS06970	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LPB138_RS06980	COG0137	argininosuccinate synthase activity
LPB138_RS06985	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LPB138_RS06990	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LPB138_RS06995	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LPB138_RS07020	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LPB138_RS07030	COG0165	Argininosuccinate lyase
LPB138_RS07035	COG1187	pseudouridine synthase activity
LPB138_RS07050	COG0494	nUDIX hydrolase
LPB138_RS07085	COG2081	HI0933 family
LPB138_RS07100	COG3104	oligopeptide transport
LPB138_RS07105	COG3104	oligopeptide transport
LPB138_RS07115	COG0658	competence protein
LPB138_RS07115	COG2333	competence protein COMEC
LPB138_RS07120	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LPB138_RS07130	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
LPB138_RS07140	COG0793	Belongs to the peptidase S41A family
LPB138_RS07145	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LPB138_RS07190	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LPB138_RS07195	COG1690	Belongs to the RtcB family
LPB138_RS07240	COG2824	Alkylphosphonate utilization operon protein PhnA
LPB138_RS07245	COG1607	acyl-coa hydrolase
LPB138_RS07255	COG2755	lipolytic protein G-D-S-L family
LPB138_RS07255	COG0657	acetylesterase activity
LPB138_RS07275	COG0745	RESPONSE REGULATOR receiver
LPB138_RS07315	COG3279	Response regulator of the LytR AlgR family
LPB138_RS07325	COG4251	negative regulation of phosphorylation
LPB138_RS07335	COG4251	negative regulation of phosphorylation
LPB138_RS07345	COG0784	Response regulator, receiver
LPB138_RS07350	COG2315	Protein conserved in bacteria
LPB138_RS07370	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LPB138_RS07380	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
LPB138_RS07390	COG1215	transferase activity, transferring glycosyl groups
LPB138_RS07410	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
LPB138_RS07410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LPB138_RS07425	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LPB138_RS07445	COG0519	Catalyzes the synthesis of GMP from XMP
LPB138_RS07455	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
LPB138_RS07460	COG2363	Small membrane protein
LPB138_RS07480	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
LPB138_RS07485	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LPB138_RS07490	COG0228	four-way junction DNA binding
LPB138_RS07520	COG1131	(ABC) transporter
LPB138_RS07555	COG2226	methyltransferase
LPB138_RS07575	COG0321	lipoyl(octanoyl) transferase activity
LPB138_RS07585	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LPB138_RS07615	COG1490	D-aminoacyl-tRNA deacylase activity
LPB138_RS07620	COG1162	GTPase activity
LPB138_RS07630	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
LPB138_RS07635	COG0287	Prephenate dehydrogenase
LPB138_RS07640	COG0436	Aminotransferase
LPB138_RS07645	COG0077	Prephenate dehydratase
LPB138_RS07650	COG4206	TonB-dependent receptor
LPB138_RS07650	COG1629	transport
LPB138_RS07690	COG1312	Catalyzes the dehydration of D-mannonate
LPB138_RS07700	COG3661	Belongs to the glycosyl hydrolase 67 family
LPB138_RS07705	COG1904	glucuronate isomerase
LPB138_RS07720	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LPB138_RS07730	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LPB138_RS07730	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
LPB138_RS07755	COG2115	Belongs to the xylose isomerase family
LPB138_RS07765	COG2706	6-phosphogluconolactonase activity
LPB138_RS07805	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
LPB138_RS07815	COG0732	type I restriction modification DNA specificity domain
LPB138_RS07825	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
LPB138_RS07875	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LPB138_RS07895	COG2329	Antibiotic biosynthesis monooxygenase
LPB138_RS07900	COG1410	methionine synthase
LPB138_RS07900	COG0646	methionine synthase
LPB138_RS07905	COG0633	Ferredoxin
LPB138_RS07910	COG0492	ferredoxin-NADP+ reductase activity
LPB138_RS07915	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LPB138_RS07915	COG1648	precorrin-2 dehydrogenase activity
LPB138_RS07920	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LPB138_RS07930	COG1959	2 iron, 2 sulfur cluster binding
LPB138_RS07950	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LPB138_RS07960	COG1428	Deoxynucleoside kinase
LPB138_RS07970	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LPB138_RS07980	COG0022	dehydrogenase e1 component
LPB138_RS07980	COG0508	dehydrogenase complex catalyzes the overall conversion of
LPB138_RS07985	COG2086	electron transfer activity
LPB138_RS07990	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
LPB138_RS08000	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LPB138_RS08005	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LPB138_RS08025	COG0616	signal peptide processing
LPB138_RS08030	COG1428	Deoxynucleoside kinase
LPB138_RS08050	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LPB138_RS08055	COG0358	DNA primase activity
LPB138_RS08060	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LPB138_RS08075	COG0544	peptidyl-prolyl cis-trans isomerase activity
LPB138_RS08080	COG1950	PFAM Membrane protein of
LPB138_RS08085	COG0596	Alpha beta hydrolase
LPB138_RS08090	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
LPB138_RS08100	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LPB138_RS08115	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LPB138_RS08130	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LPB138_RS08135	COG3279	Response regulator of the LytR AlgR family
LPB138_RS08140	COG3275	phosphorelay sensor kinase activity
LPB138_RS08155	COG0339	signal peptide processing
LPB138_RS08195	COG0348	domain, Protein
LPB138_RS08200	COG2010	Cytochrome c
LPB138_RS08210	COG3278	Belongs to the heme-copper respiratory oxidase family
LPB138_RS08250	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
LPB138_RS08270	COG0589	response to stress
LPB138_RS08290	COG0745	RESPONSE REGULATOR receiver
LPB138_RS08310	COG3118	belongs to the thioredoxin family
LPB138_RS08320	COG0750	zinc metalloprotease
LPB138_RS08360	COG0484	heat shock protein binding
LPB138_RS08385	COG1940	carbohydrate kinase activity
LPB138_RS08395	COG0577	efflux transmembrane transporter activity
LPB138_RS08395	COG1136	(ABC) transporter
LPB138_RS08425	COG1629	transport
LPB138_RS08425	COG4206	TonB-dependent receptor
LPB138_RS08530	COG3609	addiction module antidote protein, CC2985 family
LPB138_RS08605	COG1942	4-Oxalocrotonate Tautomerase
LPB138_RS08610	COG0431	NADPH-dependent FMN reductase
LPB138_RS08635	COG0667	Aldo Keto reductase
LPB138_RS08670	COG4974	Belongs to the 'phage' integrase family
LPB138_RS08710	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LPB138_RS08715	COG0535	radical SAM domain protein
LPB138_RS08740	COG0732	type I restriction modification DNA specificity domain
LPB138_RS08905	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LPB138_RS08915	COG1160	GTP binding
LPB138_RS08970	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LPB138_RS08985	COG3186	Phenylalanine-4-hydroxylase
LPB138_RS09000	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LPB138_RS09010	COG2226	methyltransferase
LPB138_RS09020	COG1477	protein flavinylation
LPB138_RS09035	COG0513	Belongs to the DEAD box helicase family
LPB138_RS09050	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LPB138_RS09055	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LPB138_RS09060	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LPB138_RS09065	COG1805	sodium ion transport
LPB138_RS09070	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LPB138_RS09080	COG2967	ApaG domain
LPB138_RS09095	COG1012	belongs to the aldehyde dehydrogenase family
LPB138_RS09105	COG0357	Ribosomal RNA small subunit methyltransferase G
LPB138_RS09110	COG3239	Fatty acid desaturase
LPB138_RS09130	COG1331	Highly conserved protein containing a thioredoxin domain
LPB138_RS09140	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LPB138_RS09205	COG1132	(ABC) transporter
LPB138_RS09210	COG0668	transmembrane transport
LPB138_RS09215	COG1214	PFAM Peptidase M22, glycoprotease
LPB138_RS09220	COG1538	Outer membrane efflux protein
LPB138_RS09230	COG2322	membrane
LPB138_RS09235	COG1999	signal sequence binding
LPB138_RS09255	COG1845	cytochrome c oxidase, subunit III
LPB138_RS09260	COG0109	protoheme IX farnesyltransferase activity
LPB138_RS09275	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LPB138_RS09285	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LPB138_RS09295	COG0322	excinuclease ABC activity
LPB138_RS09300	COG1752	Esterase of the alpha-beta hydrolase superfamily
LPB138_RS09305	COG1530	ribonuclease E activity
LPB138_RS09310	COG0776	regulation of translation
LPB138_RS09320	COG0629	single-stranded DNA binding
LPB138_RS09325	COG4535	Mg2 and Co2 transporter CorC
LPB138_RS09365	COG0612	Peptidase, M16
LPB138_RS09370	COG0612	Peptidase, M16
LPB138_RS09375	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LPB138_RS09380	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LPB138_RS09385	COG0220	tRNA (guanine-N7-)-methyltransferase activity
LPB138_RS09385	COG1519	Transferase
LPB138_RS09390	COG0326	Molecular chaperone. Has ATPase activity
LPB138_RS09395	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LPB138_RS09400	COG0303	'Molybdopterin
LPB138_RS09405	COG0746	molybdenum cofactor guanylyltransferase activity
LPB138_RS09405	COG0315	cyclic pyranopterin monophosphate synthase activity
LPB138_RS09410	COG0746	molybdenum cofactor guanylyltransferase activity
LPB138_RS09420	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LPB138_RS09430	COG0314	molybdopterin synthase activity
LPB138_RS09445	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LPB138_RS09450	COG0280	phosphate acetyltransferase
LPB138_RS09450	COG0281	malic enzyme
LPB138_RS09455	COG0632	four-way junction helicase activity
LPB138_RS09465	COG0509	glycine decarboxylation via glycine cleavage system
LPB138_RS09485	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LPB138_RS09505	COG2885	chlorophyll binding
LPB138_RS09525	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
LPB138_RS09535	COG1418	mRNA catabolic process
LPB138_RS09540	COG1024	Enoyl-CoA hydratase
LPB138_RS09555	COG0686	Belongs to the AlaDH PNT family
LPB138_RS09565	COG0495	leucyl-tRNA aminoacylation
LPB138_RS09575	COG0363	glucosamine-6-phosphate deaminase activity
LPB138_RS09580	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LPB138_RS09585	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LPB138_RS09590	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LPB138_RS09605	COG0803	Belongs to the bacterial solute-binding protein 9 family
LPB138_RS09610	COG1121	(ABC) transporter
LPB138_RS09620	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LPB138_RS09625	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LPB138_RS09645	COG1999	signal sequence binding
LPB138_RS09655	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LPB138_RS09675	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LPB138_RS09680	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
LPB138_RS09690	COG0156	8-amino-7-oxononanoate synthase activity
LPB138_RS09700	COG2949	membrane
LPB138_RS09710	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LPB138_RS09715	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LPB138_RS09720	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LPB138_RS09750	COG0196	riboflavin kinase activity
LPB138_RS09760	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LPB138_RS09775	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LPB138_RS09780	COG2239	Acts as a magnesium transporter
LPB138_RS09785	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LPB138_RS09800	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LPB138_RS09805	COG0463	Glycosyl transferase, family 2
LPB138_RS09815	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LPB138_RS09830	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LPB138_RS09845	COG1595	DNA-templated transcription, initiation
LPB138_RS09860	COG5002	protein histidine kinase activity
LPB138_RS09865	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
LPB138_RS09870	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LPB138_RS09905	COG3152	Membrane
LPB138_RS09910	COG0640	Transcriptional regulator
LPB138_RS09925	COG0527	aspartate kinase activity
LPB138_RS09925	COG0460	homoserine dehydrogenase
LPB138_RS09935	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
LPB138_RS09940	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LPB138_RS09945	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LPB138_RS09955	COG2166	iron-sulfur cluster assembly
LPB138_RS09960	COG2151	metal-sulfur cluster biosynthetic enzyme
LPB138_RS09975	COG1253	flavin adenine dinucleotide binding
LPB138_RS09985	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LPB138_RS10015	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LPB138_RS10015	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
LPB138_RS10030	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LPB138_RS10045	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LPB138_RS10065	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LPB138_RS10075	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LPB138_RS10085	COG0584	glycerophosphoryl diester phosphodiesterase
LPB138_RS10095	COG0590	tRNA wobble adenosine to inosine editing
LPB138_RS10100	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LPB138_RS10105	COG1404	Belongs to the peptidase S8 family
LPB138_RS10110	COG0232	Belongs to the dGTPase family. Type 2 subfamily
LPB138_RS10155	COG2095	MarC family integral membrane protein
LPB138_RS10165	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LPB138_RS10180	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LPB138_RS10185	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LPB138_RS10195	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LPB138_RS10210	COG0463	Glycosyl transferase, family 2
LPB138_RS10215	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LPB138_RS10230	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LPB138_RS10255	COG1012	belongs to the aldehyde dehydrogenase family
LPB138_RS10305	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LPB138_RS10310	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LPB138_RS10315	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LPB138_RS10320	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LPB138_RS10325	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LPB138_RS10330	COG0356	it plays a direct role in the translocation of protons across the membrane
LPB138_RS10365	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LPB138_RS10380	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LPB138_RS10390	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LPB138_RS10395	COG0069	glutamate synthase activity
LPB138_RS10400	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LPB138_RS10410	COG1388	LysM domain
LPB138_RS10415	COG0708	Exodeoxyribonuclease III
LPB138_RS10420	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LPB138_RS10425	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
LPB138_RS10435	COG1774	PSP1 C-terminal conserved region
LPB138_RS10445	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LPB138_RS10450	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LPB138_RS10455	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LPB138_RS10465	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LPB138_RS10470	COG1032	radical SAM domain protein
LPB138_RS10490	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LPB138_RS10505	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LPB138_RS10515	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LPB138_RS10520	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LPB138_RS10530	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LPB138_RS10540	COG1538	Outer membrane efflux protein
LPB138_RS10545	COG1309	transcriptional regulator
LPB138_RS10555	COG0596	Alpha beta hydrolase
LPB138_RS10565	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LPB138_RS10575	COG2819	hydrolase of the alpha beta superfamily
LPB138_RS10580	COG0756	dUTP diphosphatase activity
LPB138_RS10590	COG3842	ATPase activity
LPB138_RS10595	COG0189	ligase activity
LPB138_RS10595	COG4067	protein conserved in archaea
LPB138_RS10600	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LPB138_RS10615	COG0673	inositol 2-dehydrogenase activity
LPB138_RS10630	COG1230	cation diffusion facilitator family transporter
LPB138_RS10635	COG0698	ribose 5-phosphate isomerase
LPB138_RS10640	COG1597	lipid kinase activity
LPB138_RS10645	COG0557	exoribonuclease II activity
LPB138_RS10655	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LPB138_RS10670	COG1607	acyl-coa hydrolase
LPB138_RS10675	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
LPB138_RS10675	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LPB138_RS10695	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LPB138_RS10700	COG0445	tRNA wobble uridine modification
LPB138_RS10710	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LPB138_RS10725	COG0470	DNA polymerase III
LPB138_RS10730	COG0126	phosphoglycerate kinase activity
LPB138_RS10740	COG2610	gluconate transmembrane transporter activity
LPB138_RS10745	COG0667	Aldo Keto reductase
LPB138_RS10760	COG0180	Tryptophanyl-tRNA synthetase
LPB138_RS10770	COG1272	protein, Hemolysin III
LPB138_RS10785	COG4953	penicillin-binding protein 1C
LPB138_RS10790	COG3279	Response regulator of the LytR AlgR family
LPB138_RS10795	COG3275	phosphorelay sensor kinase activity
LPB138_RS10800	COG3275	phosphorelay sensor kinase activity
LPB138_RS10825	COG1381	Involved in DNA repair and RecF pathway recombination
LPB138_RS10830	COG4206	TonB-dependent receptor
LPB138_RS10865	COG1960	acyl-CoA dehydrogenase activity
LPB138_RS10870	COG0594	ribonuclease P activity
LPB138_RS10895	COG0793	Belongs to the peptidase S41A family
LPB138_RS10910	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
LPB138_RS10915	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LPB138_RS10930	COG0529	Catalyzes the synthesis of activated sulfate
LPB138_RS10935	COG0175	sulfate reduction
LPB138_RS10990	COG0175	sulfate reduction
LPB138_RS10995	COG1088	dTDP-glucose 4,6-dehydratase activity
LPB138_RS11005	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LPB138_RS11020	COG0151	Belongs to the GarS family
LPB138_RS11025	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LPB138_RS11030	COG5002	protein histidine kinase activity
LPB138_RS11035	COG0745	RESPONSE REGULATOR receiver
LPB138_RS11055	COG0488	(ABC) transporter
LPB138_RS11090	COG1607	acyl-coa hydrolase
LPB138_RS11110	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LPB138_RS11125	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LPB138_RS11145	COG1074	ATP-dependent DNA helicase activity
LPB138_RS11150	COG3047	cAMP biosynthetic process
LPB138_RS11150	COG2885	chlorophyll binding
LPB138_RS11175	COG0720	synthase
LPB138_RS11180	COG0193	aminoacyl-tRNA hydrolase activity
LPB138_RS11185	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
LPB138_RS11190	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LPB138_RS11200	COG1475	DNA binding
LPB138_RS11235	COG0629	single-stranded DNA binding
LPB138_RS11340	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LPB138_RS11360	COG2217	Heavy metal translocating P-type atpase
LPB138_RS11375	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LPB138_RS11385	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
LPB138_RS11410	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LPB138_RS11415	COG3174	membrane
LPB138_RS11420	COG0205	6-phosphofructokinase activity
LPB138_RS11430	COG1301	dicarboxylic acid transport
LPB138_RS11435	COG1830	Aldolase
LPB138_RS11515	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LPB138_RS11525	COG2132	Multicopper oxidase
LPB138_RS11560	COG0701	Predicted permease
LPB138_RS11575	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LPB138_RS11610	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LPB138_RS11625	COG2217	Heavy metal translocating P-type atpase
LPB138_RS11665	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LPB138_RS11670	COG0714	Associated with various cellular activities
LPB138_RS11685	COG2304	oxidoreductase activity
LPB138_RS11690	COG2304	oxidoreductase activity
LPB138_RS11725	COG0288	reversible hydration of carbon dioxide
LPB138_RS11735	COG0659	secondary active sulfate transmembrane transporter activity
LPB138_RS11755	COG1028	Short-chain dehydrogenase reductase Sdr
LPB138_RS11770	COG0792	nuclease activity
LPB138_RS11775	COG1619	proteins homologs of microcin C7 resistance protein MccF
LPB138_RS11780	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LPB138_RS11780	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LPB138_RS11820	COG0450	alkyl hydroperoxide reductase
LPB138_RS11840	COG0629	single-stranded DNA binding
LPB138_RS11865	COG0469	pyruvate kinase activity
LPB138_RS11875	COG0571	ribonuclease III activity
LPB138_RS11880	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LPB138_RS11885	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LPB138_RS11890	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LPB138_RS11895	COG3341	Caulimovirus viroplasmin
LPB138_RS11895	COG0328	RNA-DNA hybrid ribonuclease activity
LPB138_RS11900	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LPB138_RS11910	COG0719	Fe-S assembly protein
LPB138_RS11915	COG0396	ATPase activity
LPB138_RS11920	COG0719	Fe-S assembly protein
LPB138_RS11925	COG0316	Belongs to the HesB IscA family
LPB138_RS11950	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LPB138_RS11960	COG0346	lactoylglutathione lyase activity
LPB138_RS11970	COG0527	aspartate kinase activity
LPB138_RS11975	COG0006	proline dipeptidase activity
LPB138_RS11985	COG1053	succinate dehydrogenase
LPB138_RS11990	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LPB138_RS12040	COG0166	Belongs to the GPI family
LPB138_RS12055	COG3483	tryptophan 2,3-dioxygenase activity
LPB138_RS12060	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
LPB138_RS12065	COG0489	protein tyrosine kinase activity
LPB138_RS12075	COG0220	tRNA (guanine-N7-)-methyltransferase activity
LPB138_RS12090	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LPB138_RS12095	COG1652	LysM domain
LPB138_RS12110	COG0194	GDP metabolic process
LPB138_RS12115	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LPB138_RS12120	COG0739	heme binding
LPB138_RS12135	COG1970	mechanosensitive ion channel activity
LPB138_RS12140	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LPB138_RS12145	COG1435	thymidine kinase activity
LPB138_RS12185	COG1040	competence protein
LPB138_RS12200	COG0423	glycine-tRNA ligase activity
LPB138_RS12220	COG2217	Heavy metal translocating P-type atpase
LPB138_RS12250	COG0084	hydrolase, TatD family'
LPB138_RS12260	COG1595	DNA-templated transcription, initiation
LPB138_RS12285	COG0508	dehydrogenase complex catalyzes the overall conversion of
LPB138_RS12310	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LPB138_RS12320	COG0297	glycogen (starch) synthase activity
LPB138_RS12325	COG0481	GTPase activity
LPB138_RS12345	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LPB138_RS12355	COG4585	Histidine kinase
LPB138_RS12370	COG0346	lactoylglutathione lyase activity
LPB138_RS12375	COG2177	Part of the ABC transporter FtsEX involved in
LPB138_RS12385	COG1968	undecaprenyl-diphosphatase activity
LPB138_RS12390	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LPB138_RS12410	COG3590	peptidase
LPB138_RS12415	COG0166	Belongs to the GPI family
LPB138_RS12420	COG2137	regulation of response to DNA damage stimulus
LPB138_RS12435	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LPB138_RS12450	COG1309	transcriptional regulator
LPB138_RS12470	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
LPB138_RS12480	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LPB138_RS12485	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LPB138_RS12490	COG0511	ligase activity, forming carbon-carbon bonds
LPB138_RS12495	COG0439	Biotin carboxylase
LPB138_RS12505	COG0252	asparaginase activity
LPB138_RS12515	COG0811	peptide transport
LPB138_RS12545	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
LPB138_RS12550	COG0017	Asparaginyl-tRNA synthetase
LPB138_RS12565	COG0233	cytoplasmic translational termination
LPB138_RS12570	COG0528	UMP kinase activity
LPB138_RS12580	COG3525	Glycosyl hydrolase, family 20, catalytic domain
LPB138_RS12585	COG0363	glucosamine-6-phosphate deaminase activity
LPB138_RS12590	COG3279	Response regulator of the LytR AlgR family
LPB138_RS12600	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LPB138_RS12605	COG0052	Belongs to the universal ribosomal protein uS2 family
LPB138_RS12610	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LPB138_RS12615	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LPB138_RS12625	COG0463	Glycosyl transferase, family 2
LPB138_RS12635	COG2264	protein methyltransferase activity
LPB138_RS12650	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LPB138_RS12650	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LPB138_RS12655	COG1408	metallophosphoesterase
LPB138_RS12660	COG3118	belongs to the thioredoxin family
LPB138_RS12680	COG0589	response to stress
LPB138_RS12685	COG0779	Required for maturation of 30S ribosomal subunits
LPB138_RS12690	COG0195	Participates in both transcription termination and antitermination
LPB138_RS12690	COG2251	uridine kinase activity
LPB138_RS12695	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LPB138_RS12710	COG0437	4 iron, 4 sulfur cluster binding
LPB138_RS12735	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LPB138_RS12740	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LPB138_RS12745	COG2255	four-way junction helicase activity
LPB138_RS12780	COG0513	Belongs to the DEAD box helicase family
LPB138_RS12795	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LPB138_RS12815	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
LPB138_RS12825	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
LPB138_RS12870	COG0606	chelatase, subunit chli
LPB138_RS12875	COG1733	regulation of RNA biosynthetic process
LPB138_RS12880	COG0604	alcohol dehydrogenase
LPB138_RS12900	COG1609	Transcriptional regulator
LPB138_RS12910	COG3622	Belongs to the hyi family
LPB138_RS12925	COG3345	alpha-galactosidase
LPB138_RS12930	COG4206	TonB-dependent receptor
LPB138_RS12930	COG1629	transport
LPB138_RS12945	COG4124	Belongs to the glycosyl hydrolase 26 family
LPB138_RS12960	COG0644	oxidoreductase
LPB138_RS12965	COG2207	Transcriptional regulator
LPB138_RS12975	COG2814	Major facilitator Superfamily
LPB138_RS12980	COG0673	inositol 2-dehydrogenase activity
LPB138_RS12985	COG0673	inositol 2-dehydrogenase activity
LPB138_RS13015	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LPB138_RS13020	COG0673	inositol 2-dehydrogenase activity
LPB138_RS13025	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LPB138_RS13085	COG2366	antibiotic biosynthetic process
LPB138_RS13090	COG2169	Transcriptional regulator
LPB138_RS13100	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
LPB138_RS13105	COG2942	2-epimerase
LPB138_RS13110	COG1629	transport
LPB138_RS13110	COG4206	TonB-dependent receptor
LPB138_RS13115	COG0561	phosphatase activity
LPB138_RS13145	COG4232	protein-disulfide reductase activity
LPB138_RS13150	COG0037	tRNA processing
LPB138_RS13155	COG0596	Alpha beta hydrolase
LPB138_RS13160	COG0791	NLP P60 protein
LPB138_RS13160	COG1388	LysM domain
LPB138_RS13165	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LPB138_RS13175	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LPB138_RS13190	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LPB138_RS13195	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LPB138_RS13205	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LPB138_RS13215	COG4191	Histidine kinase
LPB138_RS13230	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
LPB138_RS13250	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LPB138_RS13255	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LPB138_RS13265	COG0820	rRNA (adenine-C2-)-methyltransferase activity
LPB138_RS13290	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LPB138_RS13300	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LPB138_RS13315	COG1045	serine acetyltransferase
LPB138_RS13320	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LPB138_RS13330	COG0129	dihydroxy-acid dehydratase activity
LPB138_RS13335	COG0028	Belongs to the TPP enzyme family
LPB138_RS13340	COG0440	acetolactate synthase activity
LPB138_RS13345	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LPB138_RS13355	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LPB138_RS13375	COG0564	pseudouridine synthase activity
LPB138_RS13380	COG0218	Necessary for normal cell division and for the maintenance of normal septation
LPB138_RS13390	COG2001	Belongs to the MraZ family
LPB138_RS13395	COG0275	rRNA processing
LPB138_RS13410	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LPB138_RS13415	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LPB138_RS13420	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LPB138_RS13425	COG0772	Belongs to the SEDS family
LPB138_RS13430	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LPB138_RS13435	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LPB138_RS13450	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LPB138_RS13455	COG1610	YqeY-like protein
LPB138_RS13500	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LPB138_RS13505	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LPB138_RS13535	COG1185	polyribonucleotide nucleotidyltransferase activity
LPB138_RS13540	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LPB138_RS13550	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LPB138_RS13555	COG0191	fructose-bisphosphate aldolase activity
LPB138_RS13565	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LPB138_RS13575	COG2226	methyltransferase
LPB138_RS13580	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
LPB138_RS13605	COG0442	prolyl-tRNA aminoacylation
LPB138_RS13615	COG0268	Binds directly to 16S ribosomal RNA
LPB138_RS13620	COG0772	Belongs to the SEDS family
LPB138_RS13625	COG0768	penicillin binding
LPB138_RS13640	COG1077	Cell shape determining protein MreB Mrl
LPB138_RS13645	COG0138	bifunctional purine biosynthesis protein purh
LPB138_RS13685	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LPB138_RS13700	COG0459	protein refolding
LPB138_RS13705	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LPB138_RS13725	COG2204	response regulator
LPB138_RS13730	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LPB138_RS13750	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LPB138_RS13780	COG0488	(ABC) transporter
LPB138_RS13785	COG2515	1-aminocyclopropane-1-carboxylate deaminase
LPB138_RS13790	COG1705	Flagellar rod assembly protein muramidase FlgJ
LPB138_RS13815	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LPB138_RS13845	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LPB138_RS13855	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LPB138_RS13865	COG3239	Fatty acid desaturase
LPB138_RS13875	COG0187	DNA topoisomerase II activity
LPB138_RS13880	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LPB138_RS13880	COG0519	Catalyzes the synthesis of GMP from XMP
LPB138_RS13885	COG1388	LysM domain
LPB138_RS13885	COG3858	chitin binding
LPB138_RS13900	COG1333	cytochrome c biogenesis protein
LPB138_RS13900	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LPB138_RS13905	COG0667	Aldo Keto reductase
LPB138_RS13920	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LPB138_RS13920	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LPB138_RS13925	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LPB138_RS13935	COG0572	uridine kinase
LPB138_RS13945	COG1215	transferase activity, transferring glycosyl groups
LPB138_RS13955	COG1696	Membrane protein involved in D-alanine export
LPB138_RS13960	COG1088	dTDP-glucose 4,6-dehydratase activity
LPB138_RS13970	COG0492	ferredoxin-NADP+ reductase activity
LPB138_RS13990	COG0154	amidase activity
LPB138_RS13995	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LPB138_RS14000	COG1446	asparaginase
LPB138_RS14010	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LPB138_RS14015	COG0512	Glutamine amidotransferase of anthranilate synthase
LPB138_RS14020	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LPB138_RS14025	COG0134	indole-3-glycerol-phosphate synthase activity
LPB138_RS14035	COG0159	tryptophan synthase activity
LPB138_RS14075	COG2884	Cell division ATP-binding protein ftsE
LPB138_RS14095	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LPB138_RS14125	COG3530	Putative quorum-sensing-regulated virulence factor
LPB138_RS14190	COG4771	TonB-dependent receptor
LPB138_RS14200	COG0450	alkyl hydroperoxide reductase
LPB138_RS14205	COG2877	3-deoxy-8-phosphooctulonate synthase activity
LPB138_RS14215	COG3123	guanosine phosphorylase activity
LPB138_RS14235	COG3275	phosphorelay sensor kinase activity
LPB138_RS14245	COG4206	TonB-dependent receptor
LPB138_RS14245	COG1629	transport
LPB138_RS14250	COG2885	chlorophyll binding
LPB138_RS14265	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LPB138_RS14270	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LPB138_RS14275	COG0569	domain protein
LPB138_RS14280	COG2003	Belongs to the UPF0758 family
LPB138_RS14300	COG0367	asparagine synthase
LPB138_RS14330	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LPB138_RS14340	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LPB138_RS14360	COG4206	TonB-dependent receptor
LPB138_RS14360	COG1629	transport
LPB138_RS14370	COG1629	transport
LPB138_RS14370	COG4206	TonB-dependent receptor
LPB138_RS14380	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LPB138_RS14385	COG0049	tRNA binding
LPB138_RS14390	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LPB138_RS14395	COG0051	transcription antitermination factor activity, RNA binding
LPB138_RS14400	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LPB138_RS14405	COG0088	Forms part of the polypeptide exit tunnel
LPB138_RS14410	COG0089	rRNA binding
LPB138_RS14415	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LPB138_RS14420	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LPB138_RS14425	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LPB138_RS14430	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LPB138_RS14435	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LPB138_RS14440	COG0255	Belongs to the universal ribosomal protein uL29 family
LPB138_RS14445	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LPB138_RS14450	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LPB138_RS14455	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LPB138_RS14460	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LPB138_RS14465	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LPB138_RS14470	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LPB138_RS14475	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LPB138_RS14480	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LPB138_RS14485	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LPB138_RS14490	COG1841	ribosomal large subunit assembly
LPB138_RS14495	COG0200	Binds to the 23S rRNA
LPB138_RS14500	COG0201	protein transport
LPB138_RS14505	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LPB138_RS14510	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LPB138_RS14515	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LPB138_RS14520	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LPB138_RS14525	COG0202	RNA polymerase activity
LPB138_RS14530	COG0203	ribosomal protein L17
LPB138_RS14540	COG0505	Belongs to the CarA family
LPB138_RS14545	COG0148	phosphopyruvate hydratase activity
LPB138_RS14565	COG0598	Magnesium transport protein CorA
LPB138_RS14630	COG0129	dihydroxy-acid dehydratase activity
LPB138_RS14635	COG2610	gluconate transmembrane transporter activity
LPB138_RS14640	COG0179	Fumarylacetoacetate (FAA) hydrolase
LPB138_RS14705	COG2311	Membrane
LPB138_RS14720	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LPB138_RS14730	COG1234	tRNA 3'-trailer cleavage
LPB138_RS14745	COG0540	Belongs to the ATCase OTCase family
LPB138_RS14750	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LPB138_RS14770	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LPB138_RS14790	COG0688	phosphatidylethanolamine metabolic process
LPB138_RS14795	COG4589	Belongs to the CDS family
LPB138_RS14805	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LPB138_RS14810	COG0799	negative regulation of ribosome biogenesis
LPB138_RS14825	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LPB138_RS14835	COG0659	secondary active sulfate transmembrane transporter activity
LPB138_RS14840	COG0746	molybdenum cofactor guanylyltransferase activity
LPB138_RS14845	COG3608	succinylglutamate desuccinylase aspartoacylase
LPB138_RS14845	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
LPB138_RS14865	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LPB138_RS14870	COG1181	Belongs to the D-alanine--D-alanine ligase family
LPB138_RS14880	COG0564	pseudouridine synthase activity
LPB138_RS14910	COG3022	response to hydroperoxide
LPB138_RS14920	COG1166	arginine decarboxylase activity
LPB138_RS14925	COG0010	Belongs to the arginase family
LPB138_RS14930	COG1899	peptidyl-lysine modification to peptidyl-hypusine
LPB138_RS14945	COG0443	Heat shock 70 kDa protein
LPB138_RS14950	COG2070	2-Nitropropane dioxygenase
LPB138_RS14975	COG1960	acyl-CoA dehydrogenase activity
LPB138_RS14980	COG0183	Belongs to the thiolase family
LPB138_RS14985	COG1250	3-hydroxyacyl-CoA dehydrogenase
LPB138_RS14985	COG1024	Enoyl-CoA hydratase
LPB138_RS14995	COG4152	abc transporter atp-binding protein
LPB138_RS15000	COG1668	transmembrane transport
LPB138_RS15005	COG3264	Mechanosensitive ion channel
LPB138_RS15005	COG1196	nuclear chromosome segregation
LPB138_RS15015	COG2326	polyphosphate kinase activity
LPB138_RS15020	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LPB138_RS15030	COG1472	Belongs to the glycosyl hydrolase 3 family
LPB138_RS15040	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LPB138_RS15045	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LPB138_RS15065	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LPB138_RS15135	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LPB138_RS15145	COG0335	large ribosomal subunit rRNA binding
LPB138_RS15150	COG0336	Belongs to the RNA methyltransferase TrmD family
LPB138_RS15170	COG2890	protein-(glutamine-N5) methyltransferase activity
LPB138_RS15185	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LPB138_RS15185	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LPB138_RS15195	COG0824	Thioesterase
LPB138_RS15305	COG0401	homolog of Blt101
LPB138_RS15310	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LPB138_RS15330	COG1401	restriction endodeoxyribonuclease activity
LPB138_RS15655	COG0563	adenylate kinase activity
LPB138_RS15660	COG0133	tryptophan synthase activity
LPB138_RS15670	COG0257	Belongs to the bacterial ribosomal protein bL36 family