locus-tag	class	description
K5K97_RS00010	COG0840	transmembrane signaling receptor activity
K5K97_RS00015	COG2884	Cell division ATP-binding protein ftsE
K5K97_RS00025	COG4786	Flagellar basal body rod
K5K97_RS00030	COG1191	sigma factor activity
K5K97_RS00035	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
K5K97_RS00040	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
K5K97_RS00045	COG1684	flagellar biosynthetic protein fliR
K5K97_RS00055	COG1338	Plays a role in the flagellum-specific transport system
K5K97_RS00065	COG1580	Controls the rotational direction of flagella during chemotaxis
K5K97_RS00075	COG4786	Flagellar basal body rod
K5K97_RS00095	COG1157	protein secretion by the type III secretion system
K5K97_RS00105	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
K5K97_RS00115	COG1677	Flagellar hook-basal body complex protein FliE
K5K97_RS00125	COG1815	bacterial-type flagellum-dependent cell motility
K5K97_RS00130	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
K5K97_RS00135	COG1360	Flagellar Motor Protein
K5K97_RS00145	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K5K97_RS00155	COG1227	inorganic diphosphatase activity
K5K97_RS00160	COG2076	Multidrug Resistance protein
K5K97_RS00165	COG2076	Multidrug Resistance protein
K5K97_RS00180	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
K5K97_RS00185	COG1882	Formate acetyltransferase
K5K97_RS00190	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
K5K97_RS00195	COG0187	DNA topoisomerase II activity
K5K97_RS00210	COG0737	Belongs to the 5'-nucleotidase family
K5K97_RS00235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K5K97_RS00240	COG1126	abc transporter atp-binding protein
K5K97_RS00245	COG0765	amino acid transport
K5K97_RS00265	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
K5K97_RS00270	COG0333	Belongs to the bacterial ribosomal protein bL32 family
K5K97_RS00280	COG1484	DNA-dependent DNA replication
K5K97_RS00290	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
K5K97_RS00295	COG0237	dephospho-CoA kinase activity
K5K97_RS00300	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
K5K97_RS00305	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K5K97_RS00305	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K5K97_RS00310	COG0670	Belongs to the BI1 family
K5K97_RS00320	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
K5K97_RS00350	COG0166	Belongs to the GPI family
K5K97_RS00355	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
K5K97_RS00360	COG2081	HI0933 family
K5K97_RS00365	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
K5K97_RS00370	COG0710	3-dehydroquinate dehydratase activity
K5K97_RS00375	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
K5K97_RS00380	COG1368	sulfuric ester hydrolase activity
K5K97_RS00395	COG2030	dehydratase
K5K97_RS00400	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
K5K97_RS00405	COG1597	lipid kinase activity
K5K97_RS00410	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
K5K97_RS00415	COG0154	amidase activity
K5K97_RS00420	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
K5K97_RS00425	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
K5K97_RS00430	COG0210	DNA helicase
K5K97_RS00465	COG1217	gtp-binding protein TYPA
K5K97_RS00470	COG0483	inositol monophosphate 1-phosphatase activity
K5K97_RS00475	COG4476	Belongs to the UPF0223 family
K5K97_RS00480	COG3850	Histidine kinase
K5K97_RS00480	COG5002	protein histidine kinase activity
K5K97_RS00485	COG0745	RESPONSE REGULATOR receiver
K5K97_RS00540	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
K5K97_RS00545	COG1073	alpha beta
K5K97_RS00630	COG2151	metal-sulfur cluster biosynthetic enzyme
K5K97_RS00640	COG0825	malonyl-CoA metabolic process
K5K97_RS00645	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
K5K97_RS00650	COG0439	Biotin carboxylase
K5K97_RS00655	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
K5K97_RS00665	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
K5K97_RS00675	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
K5K97_RS00685	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K5K97_RS00690	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
K5K97_RS00700	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K5K97_RS00705	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
K5K97_RS00710	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
K5K97_RS00715	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K5K97_RS00715	COG0072	phenylalanine-tRNA ligase activity
K5K97_RS00720	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
K5K97_RS00725	COG1733	regulation of RNA biosynthetic process
K5K97_RS00735	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
K5K97_RS00740	COG1254	Belongs to the acylphosphatase family
K5K97_RS00755	COG0083	homoserine kinase activity
K5K97_RS00765	COG0640	Transcriptional regulator
K5K97_RS00770	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
K5K97_RS00780	COG0534	Mate efflux family protein
K5K97_RS00785	COG0772	Belongs to the SEDS family
K5K97_RS00795	COG3833	ABC-type maltose transport systems, permease component
K5K97_RS00800	COG1175	transmembrane transport
K5K97_RS00805	COG2182	Extracellular solute-binding protein
K5K97_RS00815	COG0366	Alpha amylase catalytic
K5K97_RS00820	COG1609	Transcriptional regulator
K5K97_RS00830	COG1132	(ABC) transporter
K5K97_RS00835	COG1132	(ABC) transporter
K5K97_RS00840	COG3763	UPF0154 protein
K5K97_RS00845	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
K5K97_RS00850	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K5K97_RS00855	COG1609	Transcriptional regulator
K5K97_RS00870	COG0668	transmembrane transport
K5K97_RS00875	COG1473	amidohydrolase
K5K97_RS00880	COG0517	IMP dehydrogenase activity
K5K97_RS00890	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
K5K97_RS00900	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
K5K97_RS00905	COG0456	acetyltransferase
K5K97_RS00915	COG1214	PFAM Peptidase M22, glycoprotease
K5K97_RS00920	COG0494	nUDIX hydrolase
K5K97_RS00925	COG1253	flavin adenine dinucleotide binding
K5K97_RS00930	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
K5K97_RS00935	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
K5K97_RS00945	COG0488	(ABC) transporter
K5K97_RS00960	COG4471	UPF0298 protein
K5K97_RS00975	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
K5K97_RS00980	COG0772	Belongs to the SEDS family
K5K97_RS00985	COG4838	Belongs to the UPF0358 family
K5K97_RS00990	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
K5K97_RS01000	COG4841	protein insertion into membrane
K5K97_RS01005	COG0569	domain protein
K5K97_RS01010	COG2197	response regulator
K5K97_RS01015	COG4585	Histidine kinase
K5K97_RS01025	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
K5K97_RS01030	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
K5K97_RS01035	COG2824	Alkylphosphonate utilization operon protein PhnA
K5K97_RS01050	COG2207	Transcriptional regulator
K5K97_RS01050	COG4753	response regulator
K5K97_RS01055	COG2972	Histidine kinase
K5K97_RS01065	COG1653	transport
K5K97_RS01070	COG0395	ABC-type sugar transport system, permease component
K5K97_RS01075	COG1175	transmembrane transport
K5K97_RS01080	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
K5K97_RS01085	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
K5K97_RS01085	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
K5K97_RS01090	COG0726	polysaccharide deacetylase
K5K97_RS01095	COG0741	lytic transglycosylase activity
K5K97_RS01100	COG1116	anion transmembrane transporter activity
K5K97_RS01105	COG4521	taurine ABC transporter
K5K97_RS01110	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K5K97_RS01115	COG0446	pyridine nucleotide-disulphide oxidoreductase
K5K97_RS01120	COG2391	methyltransferase activity
K5K97_RS01130	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
K5K97_RS01135	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K5K97_RS01140	COG1696	Membrane protein involved in D-alanine export
K5K97_RS01270	COG0735	belongs to the Fur family
K5K97_RS01275	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
K5K97_RS01280	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
K5K97_RS01285	COG1278	Cold shock
K5K97_RS01295	COG0328	RNA-DNA hybrid ribonuclease activity
K5K97_RS01300	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
K5K97_RS01315	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
K5K97_RS01325	COG4608	Belongs to the ABC transporter superfamily
K5K97_RS01330	COG0444	Belongs to the ABC transporter superfamily
K5K97_RS01335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K5K97_RS01340	COG0601	transmembrane transport
K5K97_RS01350	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
K5K97_RS01355	COG3442	glutamine amidotransferase
K5K97_RS01360	COG0686	Belongs to the AlaDH PNT family
K5K97_RS01365	COG1609	Transcriptional regulator
K5K97_RS01370	COG1482	cell wall glycoprotein biosynthetic process
K5K97_RS01380	COG0346	lactoylglutathione lyase activity
K5K97_RS01385	COG1132	(ABC) transporter
K5K97_RS01400	COG0492	ferredoxin-NADP+ reductase activity
K5K97_RS01405	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
K5K97_RS01415	COG0647	UMP catabolic process
K5K97_RS01420	COG4470	Protein conserved in bacteria
K5K97_RS01425	COG0737	Belongs to the 5'-nucleotidase family
K5K97_RS01430	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
K5K97_RS01435	COG2365	Tyrosine phosphatase family
K5K97_RS01445	COG1131	(ABC) transporter
K5K97_RS01460	COG2249	NAD(P)H dehydrogenase (quinone) activity
K5K97_RS01480	COG3964	amidohydrolase
K5K97_RS01490	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
K5K97_RS01495	COG2188	Transcriptional regulator
K5K97_RS01500	COG3588	fructose-bisphosphate aldolase
K5K97_RS01505	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
K5K97_RS01510	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
K5K97_RS01515	COG0116	Belongs to the methyltransferase superfamily
K5K97_RS01535	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K5K97_RS01540	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
K5K97_RS01555	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
K5K97_RS01560	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
K5K97_RS01565	COG0009	L-threonylcarbamoyladenylate synthase
K5K97_RS01570	COG2890	protein-(glutamine-N5) methyltransferase activity
K5K97_RS01575	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
K5K97_RS01580	COG1435	thymidine kinase activity
K5K97_RS01585	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
K5K97_RS01590	COG0628	permease
K5K97_RS01600	COG2706	6-phosphogluconolactonase activity
K5K97_RS01605	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
K5K97_RS01620	COG2855	membrane
K5K97_RS01625	COG1335	isochorismatase
K5K97_RS01630	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
K5K97_RS01645	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
K5K97_RS01650	COG3853	Toxic anion resistance protein (TelA)
K5K97_RS01665	COG1074	ATP-dependent DNA helicase activity
K5K97_RS01670	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
K5K97_RS01690	COG1396	sequence-specific DNA binding
K5K97_RS01695	COG2807	transmembrane transport
K5K97_RS01710	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
K5K97_RS01725	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
K5K97_RS01740	COG1363	Peptidase, m42
K5K97_RS01745	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
K5K97_RS01750	COG3425	synthase
K5K97_RS01765	COG0577	efflux transmembrane transporter activity
K5K97_RS01765	COG1136	(ABC) transporter
K5K97_RS01770	COG0577	efflux transmembrane transporter activity
K5K97_RS01770	COG1136	(ABC) transporter
K5K97_RS01780	COG3328	transposase activity
K5K97_RS01785	COG0681	Belongs to the peptidase S26 family
K5K97_RS01795	COG1522	sequence-specific DNA binding
K5K97_RS01800	COG1335	isochorismatase
K5K97_RS01825	COG0504	CTP synthase activity
K5K97_RS01860	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
K5K97_RS01865	COG0351	phosphomethylpyrimidine kinase
K5K97_RS01870	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
K5K97_RS01875	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K5K97_RS01880	COG0427	acetyl-CoA hydrolase
K5K97_RS01885	COG1024	Enoyl-CoA hydratase
K5K97_RS01890	COG1250	3-hydroxyacyl-CoA dehydrogenase
K5K97_RS01895	COG1960	acyl-CoA dehydrogenase activity
K5K97_RS01900	COG0183	Belongs to the thiolase family
K5K97_RS01905	COG0583	DNA-binding transcription factor activity
K5K97_RS01910	COG1960	acyl-CoA dehydrogenase activity
K5K97_RS01915	COG0366	Alpha amylase catalytic
K5K97_RS01920	COG0395	ABC-type sugar transport system, permease component
K5K97_RS01925	COG1175	transmembrane transport
K5K97_RS01930	COG1653	transport
K5K97_RS01955	COG1428	Deoxynucleoside kinase
K5K97_RS01965	COG0590	tRNA wobble adenosine to inosine editing
K5K97_RS01970	COG2508	Transcriptional regulator
K5K97_RS01975	COG2738	Putative neutral zinc metallopeptidase
K5K97_RS01985	COG2199	diguanylate cyclase activity
K5K97_RS01995	COG0716	FMN binding
K5K97_RS02000	COG0509	glycine decarboxylation via glycine cleavage system
K5K97_RS02005	COG1393	Belongs to the ArsC family
K5K97_RS02020	COG0772	Belongs to the SEDS family
K5K97_RS02030	COG0300	oxidoreductase activity
K5K97_RS02045	COG1108	ABC-type Mn2 Zn2 transport systems permease components
K5K97_RS02050	COG1121	(ABC) transporter
K5K97_RS02055	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
K5K97_RS02070	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
K5K97_RS02075	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K5K97_RS02080	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
K5K97_RS02095	COG1304	FMN binding
K5K97_RS02100	COG3655	Transcriptional regulator
K5K97_RS02120	COG1323	Belongs to the UPF0348 family
K5K97_RS02125	COG2226	methyltransferase
K5K97_RS02130	COG0799	negative regulation of ribosome biogenesis
K5K97_RS02140	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
K5K97_RS02145	COG1534	Rna-binding protein
K5K97_RS02150	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
K5K97_RS02165	COG0138	bifunctional purine biosynthesis protein purh
K5K97_RS02170	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
K5K97_RS02175	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
K5K97_RS02185	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
K5K97_RS02195	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
K5K97_RS02200	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
K5K97_RS02210	COG4808	Protein conserved in bacteria
K5K97_RS02215	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
K5K97_RS02220	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
K5K97_RS02225	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
K5K97_RS02230	COG1070	Carbohydrate kinase
K5K97_RS02255	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
K5K97_RS02260	COG1228	amidohydrolase
K5K97_RS02265	COG1597	lipid kinase activity
K5K97_RS02270	COG0456	acetyltransferase
K5K97_RS02275	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K5K97_RS02280	COG0124	histidyl-tRNA synthetase
K5K97_RS02290	COG0531	amino acid
K5K97_RS02300	COG2759	Belongs to the formate--tetrahydrofolate ligase family
K5K97_RS02305	COG3404	Formiminotransferase-cyclodeaminase
K5K97_RS02320	COG1609	Transcriptional regulator
K5K97_RS02325	COG1486	melibiose metabolic process
K5K97_RS02335	COG1464	Belongs to the NlpA lipoprotein family
K5K97_RS02340	COG2011	ABC-type metal ion transport system permease component
K5K97_RS02345	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
K5K97_RS02355	COG1268	BioY protein
K5K97_RS02365	COG0765	amino acid transport
K5K97_RS02370	COG0765	amino acid transport
K5K97_RS02375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K5K97_RS02380	COG1126	abc transporter atp-binding protein
K5K97_RS02390	COG4946	Tricorn protease homolog
K5K97_RS02390	COG0823	Involved in the tonB-independent uptake of proteins
K5K97_RS02390	COG1506	peptidase
K5K97_RS02400	COG0488	(ABC) transporter
K5K97_RS02405	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
K5K97_RS02425	COG0367	asparagine synthase
K5K97_RS02435	COG0745	RESPONSE REGULATOR receiver
K5K97_RS02480	COG0246	Mannitol dehydrogenase
K5K97_RS02485	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
K5K97_RS02490	COG2213	PTS system mannitol-specific
K5K97_RS02495	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
K5K97_RS02500	COG3711	transcriptional antiterminator
K5K97_RS02505	COG2213	PTS system mannitol-specific
K5K97_RS02510	COG3711	transcriptional antiterminator
K5K97_RS02515	COG1263	PTS System
K5K97_RS02515	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K5K97_RS02515	COG2190	(PTS) system
K5K97_RS02550	COG4975	Glucose uptake
K5K97_RS02555	COG1869	D-ribose catabolic process
K5K97_RS02565	COG1609	Transcriptional regulator
K5K97_RS02575	COG1305	Transglutaminase-like
K5K97_RS02600	COG0431	NADPH-dependent FMN reductase
K5K97_RS02600	COG1053	succinate dehydrogenase
K5K97_RS02600	COG3976	FMN-binding domain protein
K5K97_RS02620	COG0105	UTP biosynthetic process
K5K97_RS02625	COG0513	Belongs to the DEAD box helicase family
K5K97_RS02640	COG0159	tryptophan synthase activity
K5K97_RS02655	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
K5K97_RS02660	COG1695	Transcriptional regulator
K5K97_RS02670	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
K5K97_RS02675	COG3639	organic phosphonate transmembrane transporter activity
K5K97_RS02705	COG0662	Cupin 2, conserved barrel domain protein
K5K97_RS02710	COG0531	amino acid
K5K97_RS02715	COG0351	phosphomethylpyrimidine kinase
K5K97_RS02720	COG0352	thiamine-phosphate diphosphorylase activity
K5K97_RS02725	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
K5K97_RS02735	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
K5K97_RS02765	COG0022	dehydrogenase e1 component
K5K97_RS02770	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
K5K97_RS02795	COG3730	PTS system glucitol sorbitol-specific
K5K97_RS02800	COG3732	PTS system glucitol sorbitol-specific
K5K97_RS02810	COG1063	alcohol dehydrogenase
K5K97_RS02820	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
K5K97_RS02825	COG0698	ribose 5-phosphate isomerase
K5K97_RS02835	COG3775	system Galactitol-specific IIC component
K5K97_RS02840	COG3414	Phosphotransferase system galactitol-specific IIB component
K5K97_RS02855	COG1349	DNA-binding transcription factor activity
K5K97_RS02860	COG0280	phosphate acetyltransferase
K5K97_RS02865	COG1012	belongs to the aldehyde dehydrogenase family
K5K97_RS02875	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
K5K97_RS02885	COG1454	alcohol dehydrogenase
K5K97_RS02895	COG1288	antiporter activity
K5K97_RS02905	COG0698	ribose 5-phosphate isomerase
K5K97_RS02915	COG2169	Transcriptional regulator
K5K97_RS02935	COG0604	alcohol dehydrogenase
K5K97_RS02960	COG3732	PTS system glucitol sorbitol-specific
K5K97_RS02965	COG3730	PTS system glucitol sorbitol-specific
K5K97_RS02985	COG4684	Psort location CytoplasmicMembrane, score
K5K97_RS02990	COG0564	pseudouridine synthase activity
K5K97_RS03000	COG1175	transmembrane transport
K5K97_RS03005	COG0395	ABC-type sugar transport system, permease component
K5K97_RS03020	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
K5K97_RS03025	COG1262	PFAM Formylglycine-generating sulfatase enzyme
K5K97_RS03055	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
K5K97_RS03065	COG1132	(ABC) transporter
K5K97_RS03070	COG1132	(ABC) transporter
K5K97_RS03080	COG0217	transcriptional regulatory protein
K5K97_RS03085	COG1187	pseudouridine synthase activity
K5K97_RS03100	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
K5K97_RS03105	COG0745	RESPONSE REGULATOR receiver
K5K97_RS03120	COG1132	(ABC) transporter
K5K97_RS03130	COG2814	Major facilitator Superfamily
K5K97_RS03135	COG1846	Transcriptional regulator
K5K97_RS03140	COG0667	Aldo Keto reductase
K5K97_RS03145	COG0789	Transcriptional regulator
K5K97_RS03160	COG2723	6-phospho-beta-galactosidase activity
K5K97_RS03165	COG2188	Transcriptional regulator
K5K97_RS03170	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
K5K97_RS03175	COG1940	carbohydrate kinase activity
K5K97_RS03180	COG2723	6-phospho-beta-galactosidase activity
K5K97_RS03185	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
K5K97_RS03190	COG1737	Transcriptional regulator
K5K97_RS03200	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
K5K97_RS03210	COG0673	inositol 2-dehydrogenase activity
K5K97_RS03220	COG4166	transmembrane transport
K5K97_RS03225	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K5K97_RS03230	COG1737	Transcriptional regulator
K5K97_RS03250	COG0395	ABC-type sugar transport system, permease component
K5K97_RS03255	COG1175	transmembrane transport
K5K97_RS03260	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
K5K97_RS03275	COG4166	transmembrane transport
K5K97_RS03280	COG4166	transmembrane transport
K5K97_RS03315	COG1573	uracil-dna glycosylase
K5K97_RS03340	COG1070	Carbohydrate kinase
K5K97_RS03345	COG1028	Short-chain dehydrogenase reductase Sdr
K5K97_RS03350	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
K5K97_RS03360	COG0277	FAD linked oxidase domain protein
K5K97_RS03370	COG2271	Major facilitator Superfamily
K5K97_RS03380	COG1174	glycine betaine transport
K5K97_RS03390	COG1174	glycine betaine transport
K5K97_RS03395	COG0542	response to heat
K5K97_RS03440	COG0556	nucleotide-excision repair
K5K97_RS03485	COG1401	restriction endodeoxyribonuclease activity
K5K97_RS03505	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
K5K97_RS03510	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K5K97_RS03520	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
K5K97_RS03535	COG5002	protein histidine kinase activity
K5K97_RS03540	COG0745	RESPONSE REGULATOR receiver
K5K97_RS03560	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
K5K97_RS03565	COG1780	Probably involved in ribonucleotide reductase function
K5K97_RS03570	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
K5K97_RS03575	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
K5K97_RS03585	COG4862	establishment of competence for transformation
K5K97_RS03590	COG1393	Belongs to the ArsC family
K5K97_RS03595	COG0180	Tryptophanyl-tRNA synthetase
K5K97_RS03600	COG0740	serine-type endopeptidase activity
K5K97_RS03605	COG0095	Lipoate-protein ligase
K5K97_RS03610	COG1234	tRNA 3'-trailer cleavage
K5K97_RS03615	COG0577	efflux transmembrane transporter activity
K5K97_RS03630	COG1363	Peptidase, m42
K5K97_RS03635	COG0577	efflux transmembrane transporter activity
K5K97_RS03640	COG1136	(ABC) transporter
K5K97_RS03650	COG0642	Histidine kinase
K5K97_RS03685	COG2011	ABC-type metal ion transport system permease component
K5K97_RS03690	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
K5K97_RS03700	COG0028	Belongs to the TPP enzyme family
K5K97_RS03710	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
K5K97_RS03715	COG0291	Belongs to the bacterial ribosomal protein bL35 family
K5K97_RS03720	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
K5K97_RS03745	COG2376	Dihydroxyacetone kinase
K5K97_RS03750	COG0371	Dehydrogenase
K5K97_RS03755	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
K5K97_RS03760	COG1461	Dihydroxyacetone kinase
K5K97_RS03765	COG2376	Dihydroxyacetone kinase
K5K97_RS03770	COG1309	transcriptional regulator
K5K97_RS03790	COG1649	PFAM Uncharacterised BCR, COG1649
K5K97_RS03800	COG1940	carbohydrate kinase activity
K5K97_RS03810	COG1609	Transcriptional regulator
K5K97_RS03820	COG0383	alpha-mannosidase activity
K5K97_RS03830	COG3328	transposase activity
K5K97_RS03840	COG1185	polyribonucleotide nucleotidyltransferase activity
K5K97_RS03845	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
K5K97_RS03850	COG0242	peptide deformylase activity
K5K97_RS03855	COG0561	phosphatase activity
K5K97_RS03860	COG2116	formate transmembrane transporter activity
K5K97_RS03865	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
K5K97_RS03875	COG1668	transmembrane transport
K5K97_RS03880	COG4152	abc transporter atp-binding protein
K5K97_RS03905	COG0322	excinuclease ABC activity
K5K97_RS03910	COG3118	belongs to the thioredoxin family
K5K97_RS03915	COG1193	negative regulation of DNA recombination
K5K97_RS03930	COG3328	transposase activity
K5K97_RS03935	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
K5K97_RS03940	COG3906	Belongs to the UPF0473 family
K5K97_RS03950	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
K5K97_RS03955	COG4472	Bacterial protein of unknown function (DUF965)
K5K97_RS03960	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K5K97_RS03970	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K5K97_RS03975	COG1363	Peptidase, m42
K5K97_RS03985	COG1694	Mazg nucleotide pyrophosphohydrolase
K5K97_RS03995	COG0220	tRNA (guanine-N7-)-methyltransferase activity
K5K97_RS04000	COG0510	thiamine kinase activity
K5K97_RS04005	COG4473	ABC transporter
K5K97_RS04010	COG1131	(ABC) transporter
K5K97_RS04015	COG0537	adenosine 5'-monophosphoramidase activity
K5K97_RS04020	COG4980	gas vesicle protein
K5K97_RS04025	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
K5K97_RS04040	COG1054	Belongs to the UPF0176 family
K5K97_RS04090	COG0363	glucosamine-6-phosphate deaminase activity
K5K97_RS04095	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
K5K97_RS04125	COG0798	PFAM Bile acid sodium symporter
K5K97_RS04180	COG1442	glycosyl transferase family 8
K5K97_RS04215	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
K5K97_RS04225	COG1609	Transcriptional regulator
K5K97_RS04240	COG0488	(ABC) transporter
K5K97_RS04250	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
K5K97_RS04260	COG0628	permease
K5K97_RS04275	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
K5K97_RS04280	COG1426	Protein conserved in bacteria
K5K97_RS04285	COG0300	oxidoreductase activity
K5K97_RS04290	COG0612	Peptidase, M16
K5K97_RS04295	COG0612	Peptidase, M16
K5K97_RS04300	COG1970	mechanosensitive ion channel activity
K5K97_RS04305	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
K5K97_RS04315	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
K5K97_RS04320	COG1108	ABC-type Mn2 Zn2 transport systems permease components
K5K97_RS04325	COG1121	(ABC) transporter
K5K97_RS04330	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
K5K97_RS04340	COG1177	transmembrane transport
K5K97_RS04345	COG1176	ABC-type spermidine putrescine transport system, permease component I
K5K97_RS04350	COG3842	ATPase activity
K5K97_RS04360	COG0604	alcohol dehydrogenase
K5K97_RS04415	COG1473	amidohydrolase
K5K97_RS04420	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
K5K97_RS04425	COG0038	chloride channel
K5K97_RS04435	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
K5K97_RS04440	COG4565	transcriptional regulatory protein
K5K97_RS04445	COG3290	protein histidine kinase activity
K5K97_RS04450	COG0812	UDP-N-acetylmuramate dehydrogenase activity
K5K97_RS04455	COG0708	Exodeoxyribonuclease III
K5K97_RS04475	COG0802	atpase or kinase
K5K97_RS04485	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
K5K97_RS04495	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K5K97_RS04495	COG2190	(PTS) system
K5K97_RS04495	COG1263	PTS System
K5K97_RS04505	COG1609	Transcriptional regulator
K5K97_RS04515	COG0280	phosphate acetyltransferase
K5K97_RS04525	COG0561	phosphatase activity
K5K97_RS04535	COG0025	NhaP-type Na H and K H
K5K97_RS04540	COG1278	Cold shock
K5K97_RS04560	COG0745	RESPONSE REGULATOR receiver
K5K97_RS04565	COG5002	protein histidine kinase activity
K5K97_RS04570	COG2433	Pfam Transposase IS66
K5K97_RS04595	COG1131	(ABC) transporter
K5K97_RS04635	COG1215	transferase activity, transferring glycosyl groups
K5K97_RS04645	COG2188	Transcriptional regulator
K5K97_RS04670	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
K5K97_RS04695	COG2217	Heavy metal translocating P-type atpase
K5K97_RS04700	COG1285	pathogenesis
K5K97_RS04705	COG0251	oxidation-reduction process
K5K97_RS04725	COG2390	Transcriptional regulator
K5K97_RS04730	COG0583	DNA-binding transcription factor activity
K5K97_RS04735	COG4166	transmembrane transport
K5K97_RS04740	COG0402	S-adenosylhomocysteine deaminase activity
K5K97_RS04745	COG0402	S-adenosylhomocysteine deaminase activity
K5K97_RS04750	COG4335	DNA alkylation repair
K5K97_RS04775	COG3448	diguanylate cyclase activity
K5K97_RS04775	COG4175	Glycine betaine
K5K97_RS04830	COG1132	(ABC) transporter
K5K97_RS04835	COG1132	(ABC) transporter
K5K97_RS04840	COG0765	amino acid transport
K5K97_RS04845	COG1126	abc transporter atp-binding protein
K5K97_RS04850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K5K97_RS04860	COG0435	Glutathione S-transferase
K5K97_RS04870	COG3022	response to hydroperoxide
K5K97_RS04875	COG2252	PERMEase
K5K97_RS04895	COG5504	Zn-dependent protease
K5K97_RS04900	COG2723	6-phospho-beta-galactosidase activity
K5K97_RS04905	COG1940	carbohydrate kinase activity
K5K97_RS04915	COG3973	AAA domain
K5K97_RS04935	COG0531	amino acid
K5K97_RS04945	COG1757	Na H antiporter
K5K97_RS04965	COG4166	transmembrane transport
K5K97_RS04980	COG1136	(ABC) transporter
K5K97_RS04985	COG0519	Catalyzes the synthesis of GMP from XMP
K5K97_RS04985	COG0518	GMP synthase (glutamine-hydrolyzing) activity
K5K97_RS04990	COG1072	(Pantothenic acid kinase))
K5K97_RS04995	COG2755	lipolytic protein G-D-S-L family
K5K97_RS05000	COG2813	Specifically methylates the guanine in position
K5K97_RS05005	COG0085	RNA polymerase activity
K5K97_RS05010	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
K5K97_RS05025	COG3711	transcriptional antiterminator
K5K97_RS05030	COG1263	PTS System
K5K97_RS05030	COG2190	(PTS) system
K5K97_RS05030	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K5K97_RS05035	COG2723	6-phospho-beta-galactosidase activity
K5K97_RS05055	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
K5K97_RS05060	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
K5K97_RS05070	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
K5K97_RS05080	COG3158	transport of potassium into the cell
K5K97_RS05085	COG0756	dUTP diphosphatase activity
K5K97_RS05095	COG4956	integral membrane protein (PIN domain superfamily)
K5K97_RS05100	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
K5K97_RS05105	COG1045	serine acetyltransferase
K5K97_RS05110	COG0215	cysteine-tRNA ligase activity
K5K97_RS05115	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
K5K97_RS05120	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
K5K97_RS05125	COG3688	RNA-binding protein containing a PIN domain
K5K97_RS05135	COG4466	Protein conserved in bacteria
K5K97_RS05150	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
K5K97_RS05155	COG4988	ABC transporter
K5K97_RS05160	COG1294	oxidase, subunit
K5K97_RS05165	COG1271	oxidase subunit
K5K97_RS05170	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K5K97_RS05175	COG0826	peptidase U32
K5K97_RS05185	COG0542	response to heat
K5K97_RS05190	COG4463	regulation of RNA biosynthetic process
K5K97_RS05385	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
K5K97_RS05390	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
K5K97_RS05395	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
K5K97_RS05400	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
K5K97_RS05405	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
K5K97_RS05410	COG0037	tRNA processing
K5K97_RS05415	COG1098	S1 RNA binding domain
K5K97_RS05425	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
K5K97_RS05430	COG2244	polysaccharide biosynthetic process
K5K97_RS05435	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
K5K97_RS05440	COG0193	aminoacyl-tRNA hydrolase activity
K5K97_RS05445	COG0039	L-malate dehydrogenase activity
K5K97_RS05455	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
K5K97_RS05465	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
K5K97_RS05520	COG3328	transposase activity
K5K97_RS05535	COG1733	regulation of RNA biosynthetic process
K5K97_RS05560	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
K5K97_RS05565	COG3328	transposase activity
K5K97_RS05570	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
K5K97_RS05580	COG1394	ATPase activity, coupled to movement of substances
K5K97_RS05585	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
K5K97_RS05590	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
K5K97_RS05595	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
K5K97_RS05600	COG1527	subunit (C
K5K97_RS05610	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
K5K97_RS05615	COG1269	ATP hydrolysis coupled proton transport
K5K97_RS05625	COG0446	pyridine nucleotide-disulphide oxidoreductase
K5K97_RS05630	COG0659	secondary active sulfate transmembrane transporter activity
K5K97_RS05655	COG3328	transposase activity
K5K97_RS05665	COG1461	Dihydroxyacetone kinase
K5K97_RS05680	COG3328	transposase activity
K5K97_RS05695	COG1764	response to oxidative stress
K5K97_RS05700	COG0686	Belongs to the AlaDH PNT family
K5K97_RS05710	COG1278	Cold shock
K5K97_RS05720	COG1733	regulation of RNA biosynthetic process
K5K97_RS05755	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
K5K97_RS05820	COG5294	Protein conserved in bacteria
K5K97_RS05840	COG3842	ATPase activity
K5K97_RS05845	COG0395	ABC-type sugar transport system, permease component
K5K97_RS05850	COG1175	transmembrane transport
K5K97_RS05855	COG1653	transport
K5K97_RS05865	COG1434	Gram-negative-bacterium-type cell wall biogenesis
K5K97_RS05880	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
K5K97_RS05890	COG0765	amino acid transport
K5K97_RS05895	COG1126	abc transporter atp-binding protein
K5K97_RS05915	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K5K97_RS05920	COG1187	pseudouridine synthase activity
K5K97_RS05925	COG2244	polysaccharide biosynthetic process
K5K97_RS05930	COG0495	leucyl-tRNA aminoacylation
K5K97_RS05935	COG1705	Flagellar rod assembly protein muramidase FlgJ
K5K97_RS05935	COG1388	LysM domain
K5K97_RS05950	COG0671	phosphoesterase, PA-phosphatase related
K5K97_RS05955	COG1242	4 iron, 4 sulfur cluster binding
K5K97_RS05960	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
K5K97_RS05965	COG1686	Belongs to the peptidase S11 family
K5K97_RS05980	COG0477	Major facilitator Superfamily
K5K97_RS05985	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
K5K97_RS06005	COG0813	purine-nucleoside phosphorylase activity
K5K97_RS06015	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
K5K97_RS06020	COG1079	Belongs to the binding-protein-dependent transport system permease family
K5K97_RS06025	COG4603	Belongs to the binding-protein-dependent transport system permease family
K5K97_RS06030	COG3845	ABC transporter
K5K97_RS06035	COG1744	ABC transporter substrate-binding protein PnrA-like
K5K97_RS06045	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
K5K97_RS06050	COG1609	Transcriptional regulator
K5K97_RS06065	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
K5K97_RS06085	COG4939	FMN-binding domain protein
K5K97_RS06100	COG0142	geranyltranstransferase activity
K5K97_RS06115	COG0488	(ABC) transporter
K5K97_RS06130	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
K5K97_RS06135	COG0305	Participates in initiation and elongation during chromosome replication
K5K97_RS06140	COG0359	binds to the 23S rRNA
K5K97_RS06145	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
K5K97_RS06150	COG0629	single-stranded DNA binding
K5K97_RS06155	COG0360	Binds together with S18 to 16S ribosomal RNA
K5K97_RS06165	COG0187	DNA topoisomerase II activity
K5K97_RS06170	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
K5K97_RS06180	COG0592	DNA-directed DNA polymerase activity
K5K97_RS06185	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
K5K97_RS06190	COG0230	Belongs to the bacterial ribosomal protein bL34 family
K5K97_RS06195	COG0594	ribonuclease P activity
K5K97_RS06200	COG0706	membrane insertase activity
K5K97_RS06210	COG1438	arginine binding
K5K97_RS06215	COG2235	arginine
K5K97_RS06220	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
K5K97_RS06225	COG0549	Belongs to the carbamate kinase family
K5K97_RS06235	COG1288	antiporter activity
K5K97_RS06240	COG0018	arginyl-trna synthetase
K5K97_RS06245	COG2153	protein acetylation
K5K97_RS06260	COG1438	arginine binding
K5K97_RS06270	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
K5K97_RS06275	COG0445	tRNA wobble uridine modification
K5K97_RS06290	COG0357	Ribosomal RNA small subunit methyltransferase G
K5K97_RS06295	COG1192	Involved in chromosome partitioning
K5K97_RS06300	COG1475	DNA binding
K5K97_RS06305	COG4481	Protein conserved in bacteria
K5K97_RS06310	COG0012	GTP binding
K5K97_RS06320	COG0516	GMP reductase activity
K5K97_RS06320	COG0517	IMP dehydrogenase activity
K5K97_RS06330	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
K5K97_RS06495	COG1114	Component of the transport system for branched-chain amino acids
K5K97_RS06500	COG0588	phosphoglycerate mutase activity
K5K97_RS06505	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
K5K97_RS06510	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
K5K97_RS06515	COG0049	tRNA binding
K5K97_RS06520	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
K5K97_RS06525	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
K5K97_RS06535	COG0051	transcription antitermination factor activity, RNA binding
K5K97_RS06540	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
K5K97_RS06545	COG0088	Forms part of the polypeptide exit tunnel
K5K97_RS06550	COG0089	rRNA binding
K5K97_RS06555	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
K5K97_RS06560	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
K5K97_RS06565	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
K5K97_RS06570	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
K5K97_RS06575	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
K5K97_RS06580	COG0255	Belongs to the universal ribosomal protein uL29 family
K5K97_RS06585	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
K5K97_RS06590	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
K5K97_RS06595	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
K5K97_RS06600	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
K5K97_RS06605	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
K5K97_RS06610	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
K5K97_RS06615	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
K5K97_RS06625	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
K5K97_RS06630	COG1841	ribosomal large subunit assembly
K5K97_RS06635	COG0200	Binds to the 23S rRNA
K5K97_RS06645	COG0563	adenylate kinase activity
K5K97_RS06650	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
K5K97_RS06655	COG0257	Belongs to the bacterial ribosomal protein bL36 family
K5K97_RS06660	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
K5K97_RS06665	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
K5K97_RS06670	COG0202	RNA polymerase activity
K5K97_RS06675	COG0203	ribosomal protein L17
K5K97_RS06680	COG1122	ATPase activity
K5K97_RS06685	COG1122	ATPase activity
K5K97_RS06700	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
K5K97_RS06705	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
K5K97_RS06745	COG1002	Type II restriction enzyme, methylase subunits
K5K97_RS06750	COG1061	Type III restriction enzyme res subunit
K5K97_RS06755	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
K5K97_RS06760	COG0346	lactoylglutathione lyase activity
K5K97_RS06770	COG1309	transcriptional regulator
K5K97_RS06810	COG1846	Transcriptional regulator
K5K97_RS06815	COG0778	Nitroreductase
K5K97_RS06820	COG3759	membrane
K5K97_RS06850	COG0475	glutathione-regulated potassium exporter activity
K5K97_RS06860	COG0494	nUDIX hydrolase
K5K97_RS06875	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K5K97_RS06880	COG0656	L-ascorbic acid biosynthetic process
K5K97_RS06890	COG0604	alcohol dehydrogenase
K5K97_RS06895	COG0446	pyridine nucleotide-disulphide oxidoreductase
K5K97_RS06905	COG1054	Belongs to the UPF0176 family
K5K97_RS06920	COG1380	Effector of murein hydrolase LrgA
K5K97_RS06925	COG1346	cytolysis
K5K97_RS06930	COG1304	FMN binding
K5K97_RS06945	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
K5K97_RS06950	COG0346	lactoylglutathione lyase activity
K5K97_RS06960	COG0583	DNA-binding transcription factor activity
K5K97_RS06965	COG0183	Belongs to the thiolase family
K5K97_RS06970	COG1250	3-hydroxyacyl-CoA dehydrogenase
K5K97_RS06975	COG1024	Enoyl-CoA hydratase
K5K97_RS06980	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
K5K97_RS06985	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
K5K97_RS07015	COG1846	Transcriptional regulator
K5K97_RS07020	COG0346	lactoylglutathione lyase activity
K5K97_RS07025	COG0346	lactoylglutathione lyase activity
K5K97_RS07030	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
K5K97_RS07035	COG0400	carboxylic ester hydrolase activity
K5K97_RS07055	COG1737	Transcriptional regulator
K5K97_RS07060	COG2723	6-phospho-beta-galactosidase activity
K5K97_RS07070	COG2323	membrane
K5K97_RS07080	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
K5K97_RS07085	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
K5K97_RS07100	COG1960	acyl-CoA dehydrogenase activity
K5K97_RS07105	COG0583	DNA-binding transcription factor activity
K5K97_RS07110	COG0183	Belongs to the thiolase family
K5K97_RS07115	COG1250	3-hydroxyacyl-CoA dehydrogenase
K5K97_RS07120	COG1024	Enoyl-CoA hydratase
K5K97_RS07125	COG0427	acetyl-CoA hydrolase
K5K97_RS07135	COG0110	maltose O-acetyltransferase activity
K5K97_RS07140	COG0561	phosphatase activity
K5K97_RS07150	COG1247	-acetyltransferase
K5K97_RS07155	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
K5K97_RS07160	COG4166	transmembrane transport
K5K97_RS07170	COG3279	Response regulator of the LytR AlgR family
K5K97_RS07200	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K5K97_RS07225	COG3414	Phosphotransferase system galactitol-specific IIB component
K5K97_RS07230	COG3775	system Galactitol-specific IIC component
K5K97_RS07240	COG3711	transcriptional antiterminator
K5K97_RS07245	COG2814	Major facilitator Superfamily
K5K97_RS07265	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K5K97_RS07275	COG1181	Belongs to the D-alanine--D-alanine ligase family
K5K97_RS07280	COG1438	arginine binding
K5K97_RS07295	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
K5K97_RS07315	COG0564	pseudouridine synthase activity
K5K97_RS07320	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K5K97_RS07325	COG3679	Belongs to the UPF0342 family
K5K97_RS07335	COG4717	serine-type aminopeptidase activity
K5K97_RS07340	COG3481	metal-dependent phosphohydrolase, HD sub domain
K5K97_RS07345	COG3764	Sortase (surface protein transpeptidase)
K5K97_RS07355	COG1181	Belongs to the D-alanine--D-alanine ligase family
K5K97_RS07360	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
K5K97_RS07370	COG0736	holo-[acyl-carrier-protein] synthase activity
K5K97_RS07390	COG1561	YicC-like family, N-terminal region
K5K97_RS07395	COG0194	GDP metabolic process
K5K97_RS07405	COG0384	phenazine biosynthesis protein PhzF
K5K97_RS07420	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
K5K97_RS07425	COG0242	peptide deformylase activity
K5K97_RS07430	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
K5K97_RS07435	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
K5K97_RS07435	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
K5K97_RS07445	COG0515	serine threonine protein kinase
K5K97_RS07445	COG2815	serine threonine protein kinase
K5K97_RS07450	COG1162	GTPase activity
K5K97_RS07455	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
K5K97_RS07460	COG1564	THIamine pyrophosphokinase
K5K97_RS07465	COG0227	Belongs to the bacterial ribosomal protein bL28 family
K5K97_RS07475	COG1461	Dihydroxyacetone kinase
K5K97_RS07480	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
K5K97_RS07485	COG0416	fatty acid biosynthetic process
K5K97_RS07490	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K5K97_RS07500	COG4608	Belongs to the ABC transporter superfamily
K5K97_RS07505	COG0601	transmembrane transport
K5K97_RS07510	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K5K97_RS07520	COG0571	ribonuclease III activity
K5K97_RS07525	COG1196	nuclear chromosome segregation
K5K97_RS07530	COG0561	phosphatase activity
K5K97_RS07535	COG0552	protein localization to endoplasmic reticulum
K5K97_RS07540	COG1349	DNA-binding transcription factor activity
K5K97_RS07545	COG1105	Belongs to the carbohydrate kinase PfkB family
K5K97_RS07550	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
K5K97_RS07550	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
K5K97_RS07550	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
K5K97_RS07555	COG1181	Belongs to the D-alanine--D-alanine ligase family
K5K97_RS07555	COG2918	glutathione biosynthetic process
K5K97_RS07560	COG2723	6-phospho-beta-galactosidase activity
K5K97_RS07565	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
K5K97_RS07570	COG2188	Transcriptional regulator
K5K97_RS07585	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
K5K97_RS07590	COG5506	Protein of unknown function (DUF1694)
K5K97_RS07595	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K5K97_RS07600	COG4605	iron ion homeostasis
K5K97_RS07605	COG4604	ABC transporter, ATP-binding protein
K5K97_RS07610	COG4607	ABC-type enterochelin transport system periplasmic component
K5K97_RS07615	COG1053	succinate dehydrogenase
K5K97_RS07615	COG3976	FMN-binding domain protein
K5K97_RS07625	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
K5K97_RS07640	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
K5K97_RS07660	COG1737	Transcriptional regulator
K5K97_RS07665	COG0415	Belongs to the DNA photolyase family
K5K97_RS07670	COG2188	Transcriptional regulator
K5K97_RS07675	COG1263	PTS System
K5K97_RS07675	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K5K97_RS07680	COG0366	Alpha amylase catalytic
K5K97_RS07685	COG1418	mRNA catabolic process
K5K97_RS07690	COG0456	acetyltransferase
K5K97_RS07695	COG2207	Transcriptional regulator
K5K97_RS07695	COG3708	Transcriptional regulator
K5K97_RS07705	COG1914	H( )-stimulated, divalent metal cation uptake system
K5K97_RS07715	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K5K97_RS07715	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K5K97_RS07720	COG0084	hydrolase, TatD family'
K5K97_RS07725	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
K5K97_RS07730	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
K5K97_RS07740	COG3842	ATPase activity
K5K97_RS07745	COG1803	Methylglyoxal synthase
K5K97_RS07755	COG4221	oxidoreductase activity
K5K97_RS07760	COG0789	Transcriptional regulator
K5K97_RS07765	COG1011	Hydrolase
K5K97_RS07780	COG1132	(ABC) transporter
K5K97_RS07785	COG1132	(ABC) transporter
K5K97_RS07795	COG3584	3D domain protein
K5K97_RS07795	COG1388	LysM domain
K5K97_RS07810	COG1309	transcriptional regulator
K5K97_RS07820	COG3859	Proton-coupled thiamine transporter YuaJ
K5K97_RS07840	COG4684	Psort location CytoplasmicMembrane, score
K5K97_RS07845	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
K5K97_RS07865	COG1692	metallophosphoesterase
K5K97_RS07875	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
K5K97_RS07880	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
K5K97_RS07885	COG0424	maF-like protein
K5K97_RS07895	COG0632	four-way junction helicase activity
K5K97_RS07900	COG2255	four-way junction helicase activity
K5K97_RS07905	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
K5K97_RS07910	COG0343	queuine tRNA-ribosyltransferase activity
K5K97_RS07925	COG1012	belongs to the aldehyde dehydrogenase family
K5K97_RS07925	COG1454	alcohol dehydrogenase
K5K97_RS07930	COG1792	Involved in formation and maintenance of cell shape
K5K97_RS07960	COG0217	transcriptional regulatory protein
K5K97_RS07970	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
K5K97_RS07980	COG4537	Required for transformation and DNA binding
K5K97_RS08010	COG0827	DNA restriction-modification system
K5K97_RS08015	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
K5K97_RS08035	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
K5K97_RS08045	COG2264	protein methyltransferase activity
K5K97_RS08050	COG1385	rRNA (uridine-N3-)-methyltransferase activity
K5K97_RS08060	COG2357	RelA SpoT domain protein
K5K97_RS08070	COG3878	Protein conserved in bacteria
K5K97_RS08080	COG0640	Transcriptional regulator
K5K97_RS08085	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
K5K97_RS08095	COG0446	pyridine nucleotide-disulphide oxidoreductase
K5K97_RS08115	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
K5K97_RS08135	COG0860	N-Acetylmuramoyl-L-alanine amidase
K5K97_RS08140	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
K5K97_RS08145	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K5K97_RS08150	COG2226	methyltransferase
K5K97_RS08160	COG2827	Endonuclease containing a URI domain
K5K97_RS08165	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
K5K97_RS08170	COG0204	Acyl-transferase
K5K97_RS08175	COG1131	(ABC) transporter
K5K97_RS08185	COG1309	transcriptional regulator
K5K97_RS08190	COG0420	3'-5' exonuclease activity
K5K97_RS08195	COG0419	ATPase involved in DNA repair
K5K97_RS08200	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
K5K97_RS08205	COG1132	(ABC) transporter
K5K97_RS08210	COG4720	Psort location CytoplasmicMembrane, score
K5K97_RS08215	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
K5K97_RS08220	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K5K97_RS08230	COG2814	Major facilitator Superfamily
K5K97_RS08235	COG4109	DRTGG domain
K5K97_RS08240	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
K5K97_RS08255	COG0583	DNA-binding transcription factor activity
K5K97_RS08260	COG4670	ketone body catabolic process
K5K97_RS08265	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
K5K97_RS08275	COG0583	DNA-binding transcription factor activity
K5K97_RS08280	COG1028	Short-chain dehydrogenase reductase Sdr
K5K97_RS08285	COG0183	Belongs to the thiolase family
K5K97_RS08305	COG1454	alcohol dehydrogenase
K5K97_RS08305	COG1012	belongs to the aldehyde dehydrogenase family
K5K97_RS08340	COG0783	Belongs to the Dps family
K5K97_RS08350	COG0459	protein refolding
K5K97_RS08365	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
K5K97_RS08370	COG0488	(ABC) transporter
K5K97_RS08375	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
K5K97_RS08385	COG1164	Oligoendopeptidase f
K5K97_RS08395	COG4116	CYTH
K5K97_RS08400	COG2357	RelA SpoT domain protein
K5K97_RS08405	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
K5K97_RS08410	COG0564	pseudouridine synthase activity
K5K97_RS08415	COG2239	Acts as a magnesium transporter
K5K97_RS08420	COG0456	acetyltransferase
K5K97_RS08430	COG1131	(ABC) transporter
K5K97_RS08435	COG0842	Transport permease protein
K5K97_RS08440	COG0251	oxidation-reduction process
K5K97_RS08445	COG0626	cystathionine gamma-synthase activity
K5K97_RS08450	COG3443	Belongs to the bacterial solute-binding protein 9 family
K5K97_RS08450	COG0803	Belongs to the bacterial solute-binding protein 9 family
K5K97_RS08455	COG0267	Belongs to the bacterial ribosomal protein bL33 family
K5K97_RS08460	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
K5K97_RS08465	COG0333	Belongs to the bacterial ribosomal protein bL32 family
K5K97_RS08485	COG3142	Participates in the control of copper homeostasis
K5K97_RS08490	COG0500	methyltransferase
K5K97_RS08495	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
K5K97_RS08500	COG0406	alpha-ribazole phosphatase activity
K5K97_RS08505	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
K5K97_RS08525	COG1597	lipid kinase activity
K5K97_RS08530	COG0431	NADPH-dependent FMN reductase
K5K97_RS08535	COG0456	acetyltransferase
K5K97_RS08550	COG0267	Belongs to the bacterial ribosomal protein bL33 family
K5K97_RS08560	COG0250	Participates in transcription elongation, termination and antitermination
K5K97_RS08570	COG1757	Na H antiporter
K5K97_RS08585	COG1760	l-serine dehydratase
K5K97_RS08590	COG1760	l-serine dehydratase
K5K97_RS08595	COG1058	Belongs to the CinA family
K5K97_RS08595	COG1546	Belongs to the CinA family
K5K97_RS08600	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
K5K97_RS08605	COG1418	mRNA catabolic process
K5K97_RS08610	COG1917	Cupin 2, conserved barrel domain protein
K5K97_RS08610	COG2207	Transcriptional regulator
K5K97_RS08615	COG0673	inositol 2-dehydrogenase activity
K5K97_RS08635	COG0673	inositol 2-dehydrogenase activity
K5K97_RS08640	COG2217	Heavy metal translocating P-type atpase
K5K97_RS08650	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
K5K97_RS08655	COG0081	regulation of translation
K5K97_RS08660	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
K5K97_RS08665	COG0222	ribosome binding
K5K97_RS08670	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
K5K97_RS08675	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
K5K97_RS08680	COG4122	O-methyltransferase activity
K5K97_RS08695	COG0261	This protein binds to 23S rRNA in the presence of protein L20
K5K97_RS08700	COG2868	ribosomal protein
K5K97_RS08705	COG0211	Belongs to the bacterial ribosomal protein bL27 family
K5K97_RS08710	COG0006	proline dipeptidase activity
K5K97_RS08715	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
K5K97_RS08720	COG1302	Protein conserved in bacteria
K5K97_RS08725	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
K5K97_RS08730	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
K5K97_RS08735	COG1570	exodeoxyribonuclease VII activity
K5K97_RS08740	COG1722	exodeoxyribonuclease VII activity
K5K97_RS08750	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
K5K97_RS08755	COG1438	arginine binding
K5K97_RS08760	COG0497	DNA recombination
K5K97_RS08775	COG2001	Belongs to the MraZ family
K5K97_RS08780	COG0275	rRNA processing
K5K97_RS08790	COG0768	penicillin binding
K5K97_RS08795	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
K5K97_RS08800	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
K5K97_RS08805	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
K5K97_RS08810	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
K5K97_RS08815	COG0849	cell division
K5K97_RS08820	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
K5K97_RS08825	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
K5K97_RS08830	COG1799	cell septum assembly
K5K97_RS08840	COG2302	S4 RNA-binding domain
K5K97_RS08845	COG3599	regulation of cell shape
K5K97_RS08850	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
K5K97_RS08860	COG1174	glycine betaine transport
K5K97_RS08875	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
K5K97_RS08885	COG0436	Aminotransferase
K5K97_RS08900	COG0006	proline dipeptidase activity
K5K97_RS08945	COG2268	Band 7 protein
K5K97_RS08960	COG0789	Transcriptional regulator
K5K97_RS08970	COG0384	phenazine biosynthesis protein PhzF
K5K97_RS08985	COG4129	membrane
K5K97_RS08995	COG1876	peptidase activity
K5K97_RS09000	COG1705	Flagellar rod assembly protein muramidase FlgJ
K5K97_RS09010	COG0681	Belongs to the peptidase S26 family
K5K97_RS09025	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
K5K97_RS09035	COG2183	response to ionizing radiation
K5K97_RS09040	COG3091	SprT-like family
K5K97_RS09060	COG3594	Acyltransferase
K5K97_RS09075	COG0561	phosphatase activity
K5K97_RS09090	COG0527	aspartate kinase activity
K5K97_RS09095	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
K5K97_RS09100	COG1104	cysteine desulfurase activity
K5K97_RS09105	COG0301	tRNA thio-modification
K5K97_RS09110	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
K5K97_RS09120	COG0525	valine-tRNA ligase activity
K5K97_RS09125	COG0285	dihydrofolate synthase activity
K5K97_RS09130	COG0546	phosphoglycolate phosphatase activity
K5K97_RS09135	COG2003	Belongs to the UPF0758 family
K5K97_RS09140	COG1278	Cold shock
K5K97_RS09150	COG5503	Protein of unknown function (DUF1447)
K5K97_RS09155	COG2388	GCN5-related N-acetyl-transferase
K5K97_RS09170	COG1132	(ABC) transporter
K5K97_RS09195	COG0513	Belongs to the DEAD box helicase family
K5K97_RS09200	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
K5K97_RS09200	COG3933	PFAM sigma-54 factor interaction domain-containing protein
K5K97_RS09210	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
K5K97_RS09230	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
K5K97_RS09235	COG1447	Phosphotransferase system cellobiose-specific component IIA
K5K97_RS09255	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
K5K97_RS09340	COG0629	single-stranded DNA binding
K5K97_RS09515	COG1316	TRANSCRIPTIONal
K5K97_RS09520	COG0745	RESPONSE REGULATOR receiver
K5K97_RS09530	COG0726	polysaccharide deacetylase
K5K97_RS09535	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
K5K97_RS09540	COG2309	aminopeptidase activity
K5K97_RS09550	COG0716	FMN binding
K5K97_RS09555	COG0024	Methionine aminopeptidase
K5K97_RS09560	COG1295	ribonuclease BN
K5K97_RS09570	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
K5K97_RS09575	COG1316	TRANSCRIPTIONal
K5K97_RS09580	COG1134	teichoic acid transport
K5K97_RS09585	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
K5K97_RS09590	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
K5K97_RS09595	COG1682	transport, permease protein
K5K97_RS09600	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
K5K97_RS09605	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
K5K97_RS09615	COG0489	protein tyrosine kinase activity
K5K97_RS09620	COG4464	protein tyrosine phosphatase activity
K5K97_RS09630	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
K5K97_RS09640	COG0438	transferase activity, transferring glycosyl groups
K5K97_RS09645	COG0438	transferase activity, transferring glycosyl groups
K5K97_RS09665	COG0463	Glycosyl transferase, family 2
K5K97_RS09675	COG1086	Polysaccharide biosynthesis protein
K5K97_RS09700	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
K5K97_RS09705	COG1316	TRANSCRIPTIONal
K5K97_RS09710	COG0589	response to stress
K5K97_RS09740	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
K5K97_RS09745	COG1210	Utp--glucose-1-phosphate uridylyltransferase
K5K97_RS09750	COG2137	regulation of response to DNA damage stimulus
K5K97_RS09755	COG1194	a g-specific adenine glycosylase
K5K97_RS09760	COG3557	Belongs to the UPF0374 family
K5K97_RS09775	COG2153	protein acetylation
K5K97_RS09780	COG0628	permease
K5K97_RS09785	COG1253	flavin adenine dinucleotide binding
K5K97_RS09790	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
K5K97_RS09810	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
K5K97_RS09820	COG0542	response to heat
K5K97_RS09835	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
K5K97_RS09840	COG0438	transferase activity, transferring glycosyl groups
K5K97_RS09845	COG0438	transferase activity, transferring glycosyl groups
K5K97_RS09855	COG2084	Dehydrogenase
K5K97_RS09860	COG4703	Protein of unknown function (DUF1797)
K5K97_RS09870	COG0544	peptidyl-prolyl cis-trans isomerase activity
K5K97_RS09875	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
K5K97_RS09885	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
K5K97_RS09890	COG0745	RESPONSE REGULATOR receiver
K5K97_RS09895	COG5002	protein histidine kinase activity
K5K97_RS09905	COG2217	Heavy metal translocating P-type atpase
K5K97_RS09920	COG2514	catechol 2,3-dioxygenase activity
K5K97_RS09925	COG0446	pyridine nucleotide-disulphide oxidoreductase
K5K97_RS09930	COG0584	glycerophosphoryl diester phosphodiesterase
K5K97_RS09935	COG1705	Flagellar rod assembly protein muramidase FlgJ
K5K97_RS09935	COG3942	CHAP domain
K5K97_RS09940	COG0218	Necessary for normal cell division and for the maintenance of normal septation
K5K97_RS09955	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K5K97_RS09960	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
K5K97_RS09970	COG0436	Aminotransferase
K5K97_RS09975	COG1126	abc transporter atp-binding protein
K5K97_RS09980	COG0765	amino acid transport
K5K97_RS09985	COG0371	Dehydrogenase
K5K97_RS09990	COG2723	6-phospho-beta-galactosidase activity
K5K97_RS10005	COG4948	Mandelate Racemase Muconate Lactonizing
K5K97_RS10015	COG4166	transmembrane transport
K5K97_RS10020	COG4166	transmembrane transport
K5K97_RS10025	COG4166	transmembrane transport
K5K97_RS10030	COG2195	Cleaves the N-terminal amino acid of tripeptides
K5K97_RS10045	COG3933	PFAM sigma-54 factor interaction domain-containing protein
K5K97_RS10045	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
K5K97_RS10050	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
K5K97_RS10050	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K5K97_RS10060	COG3715	PTS system
K5K97_RS10065	COG3716	PTS system mannose fructose sorbose family IID component
K5K97_RS10075	COG4166	transmembrane transport
K5K97_RS10085	COG0601	transmembrane transport
K5K97_RS10090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K5K97_RS10095	COG0444	Belongs to the ABC transporter superfamily
K5K97_RS10100	COG4608	Belongs to the ABC transporter superfamily
K5K97_RS10120	COG1446	asparaginase
K5K97_RS10125	COG2188	Transcriptional regulator
K5K97_RS10130	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K5K97_RS10140	COG0390	transport system, permease component
K5K97_RS10145	COG4619	ABC transporter
K5K97_RS10150	COG0572	uridine kinase
K5K97_RS10155	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
K5K97_RS10160	COG1098	S1 RNA binding domain
K5K97_RS10210	COG2246	polysaccharide biosynthetic process
K5K97_RS10220	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
K5K97_RS10220	COG1199	ATP-dependent helicase activity
K5K97_RS10230	COG0436	Aminotransferase
K5K97_RS10240	COG3711	transcriptional antiterminator
K5K97_RS10245	COG1263	PTS System
K5K97_RS10245	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K5K97_RS10245	COG2190	(PTS) system
K5K97_RS10250	COG2723	6-phospho-beta-galactosidase activity
K5K97_RS10255	COG2608	mercury ion transmembrane transporter activity
K5K97_RS10260	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
K5K97_RS10270	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
K5K97_RS10275	COG1316	TRANSCRIPTIONal
K5K97_RS10280	COG3579	cysteine-type endopeptidase activity
K5K97_RS10285	COG0556	nucleotide-excision repair
K5K97_RS10290	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
K5K97_RS10300	COG1131	(ABC) transporter
K5K97_RS10305	COG2186	Transcriptional regulator
K5K97_RS10310	COG1660	Displays ATPase and GTPase activities
K5K97_RS10320	COG1481	regulation of sporulation
K5K97_RS10325	COG3284	Transcriptional regulator
K5K97_RS10330	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K5K97_RS10335	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
K5K97_RS10340	COG0022	dehydrogenase e1 component
K5K97_RS10345	COG0508	dehydrogenase complex catalyzes the overall conversion of
K5K97_RS10370	COG0740	serine-type endopeptidase activity
K5K97_RS10380	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
K5K97_RS10385	COG2390	Transcriptional regulator
K5K97_RS10395	COG0126	phosphoglycerate kinase activity
K5K97_RS10400	COG0149	triose-phosphate isomerase activity
K5K97_RS10405	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
K5K97_RS10415	COG4974	Belongs to the 'phage' integrase family
K5K97_RS10435	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
K5K97_RS10490	COG0024	Methionine aminopeptidase
K5K97_RS10500	COG1609	Transcriptional regulator
K5K97_RS10510	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K5K97_RS10515	COG1288	antiporter activity
K5K97_RS10525	COG4988	ABC transporter
K5K97_RS10530	COG1132	(ABC) transporter
K5K97_RS10540	COG2508	Transcriptional regulator
K5K97_RS10545	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
K5K97_RS10550	COG1304	FMN binding
K5K97_RS10555	COG0666	response to abiotic stimulus
K5K97_RS10560	COG1953	Uracil, thiamine, allantoin
K5K97_RS10565	COG0590	tRNA wobble adenosine to inosine editing
K5K97_RS10605	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
K5K97_RS10625	COG0716	FMN binding
K5K97_RS10640	COG2378	regulation of single-species biofilm formation
K5K97_RS10680	COG1942	4-Oxalocrotonate Tautomerase
K5K97_RS10685	COG3397	chitin binding
K5K97_RS10700	COG0557	exoribonuclease II activity
K5K97_RS10705	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
K5K97_RS10710	COG0356	it plays a direct role in the translocation of protons across the membrane
K5K97_RS10715	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
K5K97_RS10720	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
K5K97_RS10725	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
K5K97_RS10730	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
K5K97_RS10735	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
K5K97_RS10740	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
K5K97_RS10745	COG0355	proton-transporting ATP synthase activity, rotational mechanism
K5K97_RS10760	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
K5K97_RS10770	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
K5K97_RS10780	COG0559	Belongs to the binding-protein-dependent transport system permease family
K5K97_RS10790	COG0411	ABC transporter
K5K97_RS10800	COG0517	IMP dehydrogenase activity
K5K97_RS10835	COG1309	transcriptional regulator
K5K97_RS10845	COG2188	Transcriptional regulator
K5K97_RS10850	COG1739	Uncharacterized protein family UPF0029
K5K97_RS10860	COG2267	carboxylic ester hydrolase activity
K5K97_RS10865	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
K5K97_RS10870	COG1040	competence protein
K5K97_RS10880	COG0653	protein targeting
K5K97_RS10890	COG2884	Cell division ATP-binding protein ftsE
K5K97_RS10895	COG2177	Part of the ABC transporter FtsEX involved in
K5K97_RS10910	COG0573	inorganic phosphate transmembrane transporter activity
K5K97_RS10915	COG0581	inorganic phosphate transmembrane transporter activity
K5K97_RS10920	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
K5K97_RS10925	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
K5K97_RS10930	COG0704	Plays a role in the regulation of phosphate uptake
K5K97_RS10935	COG0741	lytic transglycosylase activity
K5K97_RS10935	COG0739	heme binding
K5K97_RS10935	COG1196	nuclear chromosome segregation
K5K97_RS10950	COG1950	PFAM Membrane protein of
K5K97_RS10960	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
K5K97_RS10965	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
K5K97_RS10970	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
K5K97_RS10980	COG1073	alpha beta
K5K97_RS10985	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
K5K97_RS10990	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
K5K97_RS10995	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
K5K97_RS11000	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
K5K97_RS11005	COG3870	Protein conserved in bacteria
K5K97_RS11010	COG0470	DNA polymerase III
K5K97_RS11015	COG1774	PSP1 C-terminal conserved region
K5K97_RS11020	COG4467	Involved in initiation control of chromosome replication
K5K97_RS11040	COG1705	Flagellar rod assembly protein muramidase FlgJ
K5K97_RS11040	COG3942	CHAP domain
K5K97_RS11045	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
K5K97_RS11050	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
K5K97_RS11060	COG4989	oxidoreductase activity
K5K97_RS11065	COG1131	(ABC) transporter
K5K97_RS11075	COG0516	GMP reductase activity
K5K97_RS11080	COG2962	Rard protein
K5K97_RS11085	COG0561	phosphatase activity
K5K97_RS11090	COG1078	dGTPase activity
K5K97_RS11095	COG0095	Lipoate-protein ligase
K5K97_RS11105	COG3343	RNA polymerase activity
K5K97_RS11120	COG1012	belongs to the aldehyde dehydrogenase family
K5K97_RS11130	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
K5K97_RS11135	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
K5K97_RS11140	COG0254	rRNA binding
K5K97_RS11145	COG1660	Displays ATPase and GTPase activities
K5K97_RS11150	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
K5K97_RS11155	COG1368	sulfuric ester hydrolase activity
K5K97_RS11160	COG1476	TRANSCRIPTIONal
K5K97_RS11175	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
K5K97_RS11190	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K5K97_RS11195	COG0488	(ABC) transporter
K5K97_RS11220	COG1131	(ABC) transporter
K5K97_RS11230	COG0574	Belongs to the PEP-utilizing enzyme family
K5K97_RS11230	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
K5K97_RS11235	COG0517	IMP dehydrogenase activity
K5K97_RS11240	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
K5K97_RS11250	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
K5K97_RS11255	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
K5K97_RS11270	COG0488	(ABC) transporter
K5K97_RS11275	COG0446	pyridine nucleotide-disulphide oxidoreductase
K5K97_RS11280	COG1937	Protein conserved in bacteria
K5K97_RS11290	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
K5K97_RS11295	COG2011	ABC-type metal ion transport system permease component
K5K97_RS11300	COG1464	Belongs to the NlpA lipoprotein family
K5K97_RS11310	COG0719	Fe-S assembly protein
K5K97_RS11315	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
K5K97_RS11320	COG0822	iron-sulfur transferase activity
K5K97_RS11325	COG0719	Fe-S assembly protein
K5K97_RS11360	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
K5K97_RS11365	COG2207	Transcriptional regulator
K5K97_RS11365	COG1609	Transcriptional regulator
K5K97_RS11370	COG3250	beta-galactosidase activity
K5K97_RS11375	COG4978	Transcriptional regulator
K5K97_RS11375	COG0789	Transcriptional regulator
K5K97_RS11395	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
K5K97_RS11410	COG1882	Formate acetyltransferase
K5K97_RS11415	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
K5K97_RS11465	COG1454	alcohol dehydrogenase
K5K97_RS11465	COG1012	belongs to the aldehyde dehydrogenase family
K5K97_RS11470	COG4869	propanediol catabolic process
K5K97_RS11480	COG0446	pyridine nucleotide-disulphide oxidoreductase
K5K97_RS11540	COG4565	transcriptional regulatory protein
K5K97_RS11545	COG3290	protein histidine kinase activity
K5K97_RS11550	COG3493	citrate carrier protein
K5K97_RS11590	COG0673	inositol 2-dehydrogenase activity
K5K97_RS11595	COG2182	Extracellular solute-binding protein
K5K97_RS11600	COG1175	transmembrane transport
K5K97_RS11605	COG0395	ABC-type sugar transport system, permease component
K5K97_RS11620	COG0673	inositol 2-dehydrogenase activity
K5K97_RS11650	COG0673	inositol 2-dehydrogenase activity
K5K97_RS11675	COG2223	nitrite transmembrane transporter activity
K5K97_RS11680	COG1671	Belongs to the UPF0178 family
K5K97_RS11685	COG4807	Protein conserved in bacteria
K5K97_RS11690	COG0386	Belongs to the glutathione peroxidase family
K5K97_RS11695	COG0280	phosphate acetyltransferase
K5K97_RS11700	COG3426	butyrate kinase activity
K5K97_RS11705	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K5K97_RS11710	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
K5K97_RS11715	COG0022	dehydrogenase e1 component
K5K97_RS11720	COG0508	dehydrogenase complex catalyzes the overall conversion of
K5K97_RS11730	COG0583	DNA-binding transcription factor activity
K5K97_RS11735	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
K5K97_RS11750	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
K5K97_RS11765	COG2860	membrane
K5K97_RS11770	COG0514	ATP-dependent DNA helicase (RecQ)
K5K97_RS11780	COG1979	alcohol dehydrogenase
K5K97_RS11790	COG0583	DNA-binding transcription factor activity
K5K97_RS11820	COG0737	Belongs to the 5'-nucleotidase family
K5K97_RS11835	COG1129	ABC transporter
K5K97_RS11855	COG0656	L-ascorbic acid biosynthetic process
K5K97_RS11860	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K5K97_RS11865	COG1104	cysteine desulfurase activity
K5K97_RS11875	COG2184	nucleotidyltransferase activity
K5K97_RS11890	COG2814	Major facilitator Superfamily
K5K97_RS11905	COG0482	sulfurtransferase activity
K5K97_RS11915	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
K5K97_RS11930	COG1012	belongs to the aldehyde dehydrogenase family
K5K97_RS11935	COG1674	ftsk spoiiie
K5K97_RS11935	COG1280	lysine exporter protein (LysE YggA)
K5K97_RS11955	COG0025	NhaP-type Na H and K H
K5K97_RS11960	COG1136	(ABC) transporter
K5K97_RS11965	COG0577	efflux transmembrane transporter activity
K5K97_RS11975	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
K5K97_RS11980	COG1131	(ABC) transporter
K5K97_RS11990	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
K5K97_RS11995	COG0768	penicillin binding
K5K97_RS12000	COG0267	Belongs to the bacterial ribosomal protein bL33 family
K5K97_RS12025	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
K5K97_RS12030	COG0457	Tetratricopeptide repeat
K5K97_RS12030	COG0705	Rhomboid family
K5K97_RS12040	COG1940	carbohydrate kinase activity
K5K97_RS12045	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K5K97_RS12055	COG0584	glycerophosphoryl diester phosphodiesterase
K5K97_RS12060	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
K5K97_RS12065	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
K5K97_RS12070	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
K5K97_RS12075	COG0789	Transcriptional regulator
K5K97_RS12085	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
K5K97_RS12100	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
K5K97_RS12105	COG0742	ribosomal rna small subunit methyltransferase
K5K97_RS12110	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
K5K97_RS12115	COG3480	Lon protease (S16) C-terminal proteolytic domain
K5K97_RS12120	COG1555	photosystem II stabilization
K5K97_RS12125	COG2131	deaminase
K5K97_RS12130	COG2333	competence protein COMEC
K5K97_RS12130	COG0658	competence protein
K5K97_RS12135	COG1466	dna polymerase III delta subunit
K5K97_RS12145	COG1307	EDD domain protein, DegV family
K5K97_RS12155	COG1307	EDD domain protein, DegV family
K5K97_RS12160	COG2217	Heavy metal translocating P-type atpase
K5K97_RS12165	COG1968	undecaprenyl-diphosphatase activity
K5K97_RS12175	COG0789	Transcriptional regulator
K5K97_RS12190	COG0588	phosphoglycerate mutase activity
K5K97_RS12195	COG0052	Belongs to the universal ribosomal protein uS2 family
K5K97_RS12200	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
K5K97_RS12205	COG0528	UMP kinase activity
K5K97_RS12210	COG0233	cytoplasmic translational termination
K5K97_RS12215	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
K5K97_RS12220	COG4589	Belongs to the CDS family
K5K97_RS12225	COG0750	zinc metalloprotease
K5K97_RS12230	COG0442	prolyl-tRNA aminoacylation
K5K97_RS12240	COG1408	metallophosphoesterase
K5K97_RS12245	COG0779	Required for maturation of 30S ribosomal subunits
K5K97_RS12250	COG0195	Participates in both transcription termination and antitermination
K5K97_RS12255	COG2740	Nucleic-acid-binding protein implicated in transcription termination
K5K97_RS12270	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
K5K97_RS12275	COG0673	inositol 2-dehydrogenase activity
K5K97_RS12280	COG1363	Peptidase, m42
K5K97_RS12285	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
K5K97_RS12290	COG0196	riboflavin kinase activity
K5K97_RS12295	COG0635	Involved in the biosynthesis of porphyrin-containing compound
K5K97_RS12300	COG1420	regulation of RNA biosynthetic process
K5K97_RS12305	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
K5K97_RS12310	COG0443	Heat shock 70 kDa protein
K5K97_RS12315	COG0484	heat shock protein binding
K5K97_RS12320	COG0803	Belongs to the bacterial solute-binding protein 9 family
K5K97_RS12330	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
K5K97_RS12335	COG1132	(ABC) transporter
K5K97_RS12340	COG1132	(ABC) transporter
K5K97_RS12345	COG0745	RESPONSE REGULATOR receiver
K5K97_RS12350	COG5002	protein histidine kinase activity
K5K97_RS12355	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
K5K97_RS12360	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
K5K97_RS12380	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
K5K97_RS12385	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
K5K97_RS12390	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
K5K97_RS12395	COG2205	protein histidine kinase activity
K5K97_RS12400	COG0745	RESPONSE REGULATOR receiver
K5K97_RS12415	COG1131	(ABC) transporter
K5K97_RS12430	COG1837	Belongs to the UPF0109 family
K5K97_RS12440	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
K5K97_RS12445	COG0336	Belongs to the RNA methyltransferase TrmD family
K5K97_RS12450	COG0335	large ribosomal subunit rRNA binding
K5K97_RS12455	COG1764	response to oxidative stress
K5K97_RS12460	COG1263	PTS System
K5K97_RS12460	COG2190	(PTS) system
K5K97_RS12460	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K5K97_RS12465	COG2723	6-phospho-beta-galactosidase activity
K5K97_RS12470	COG3711	transcriptional antiterminator
K5K97_RS12475	COG3711	transcriptional antiterminator
K5K97_RS12480	COG1193	negative regulation of DNA recombination
K5K97_RS12510	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K5K97_RS12515	COG1522	sequence-specific DNA binding
K5K97_RS12520	COG0436	Aminotransferase
K5K97_RS12530	COG3711	transcriptional antiterminator
K5K97_RS12535	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K5K97_RS12535	COG1263	PTS System
K5K97_RS12535	COG2190	(PTS) system
K5K97_RS12540	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
K5K97_RS12545	COG0577	efflux transmembrane transporter activity
K5K97_RS12550	COG1136	(ABC) transporter
K5K97_RS12560	COG0745	RESPONSE REGULATOR receiver
K5K97_RS12570	COG1609	Transcriptional regulator
K5K97_RS12580	COG0772	Belongs to the SEDS family
K5K97_RS12600	COG4753	response regulator
K5K97_RS12600	COG2207	Transcriptional regulator
K5K97_RS12610	COG1027	Aspartate ammonia-lyase
K5K97_RS12615	COG0281	malic enzyme
K5K97_RS12620	COG0114	fumarate hydratase activity
K5K97_RS12630	COG0745	RESPONSE REGULATOR receiver
K5K97_RS12635	COG5002	protein histidine kinase activity
K5K97_RS12650	COG0820	rRNA (adenine-C2-)-methyltransferase activity
K5K97_RS12655	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
K5K97_RS12660	COG4166	transmembrane transport
K5K97_RS12665	COG0477	Major facilitator Superfamily
K5K97_RS12670	COG0404	The glycine cleavage system catalyzes the degradation of glycine
K5K97_RS12675	COG0509	glycine decarboxylation via glycine cleavage system
K5K97_RS12680	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
K5K97_RS12685	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
K5K97_RS12715	COG0406	alpha-ribazole phosphatase activity
K5K97_RS12725	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
K5K97_RS12730	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
K5K97_RS12735	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
K5K97_RS12740	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
K5K97_RS12745	COG0287	Prephenate dehydrogenase
K5K97_RS12755	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
K5K97_RS12760	COG0077	Prephenate dehydratase
K5K97_RS12770	COG1307	EDD domain protein, DegV family
K5K97_RS12775	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
K5K97_RS12785	COG0513	Belongs to the DEAD box helicase family
K5K97_RS12790	COG1959	2 iron, 2 sulfur cluster binding
K5K97_RS12795	COG2910	NAD(P)H-binding
K5K97_RS12800	COG2153	protein acetylation
K5K97_RS12805	COG2267	carboxylic ester hydrolase activity
K5K97_RS12810	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
K5K97_RS12815	COG1136	(ABC) transporter
K5K97_RS12820	COG0577	efflux transmembrane transporter activity
K5K97_RS12860	COG3645	SOS response
K5K97_RS12860	COG3646	Phage regulatory protein
K5K97_RS12935	COG0629	single-stranded DNA binding
K5K97_RS13010	COG5484	DNA packaging
K5K97_RS13010	COG3728	DNA packaging
K5K97_RS13115	COG3594	Acyltransferase
K5K97_RS13165	COG1131	(ABC) transporter
K5K97_RS13170	COG1725	Transcriptional regulator
K5K97_RS13185	COG2814	Major facilitator Superfamily
K5K97_RS13195	COG0587	DNA-directed DNA polymerase activity
K5K97_RS13200	COG0205	6-phosphofructokinase activity
K5K97_RS13210	COG2814	Major facilitator Superfamily
K5K97_RS13225	COG2996	Protein conserved in bacteria
K5K97_RS13230	COG0735	belongs to the Fur family
K5K97_RS13235	COG0519	Catalyzes the synthesis of GMP from XMP
K5K97_RS13245	COG4974	Belongs to the 'phage' integrase family
K5K97_RS13250	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
K5K97_RS13255	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
K5K97_RS13260	COG1187	pseudouridine synthase activity
K5K97_RS13265	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
K5K97_RS13270	COG2755	lipolytic protein G-D-S-L family
K5K97_RS13270	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
K5K97_RS13285	COG0514	ATP-dependent DNA helicase (RecQ)
K5K97_RS13290	COG1388	LysM domain
K5K97_RS13290	COG1134	teichoic acid transport
K5K97_RS13295	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
K5K97_RS13300	COG0539	negative regulation of cytoplasmic translation
K5K97_RS13305	COG1160	GTP binding
K5K97_RS13330	COG5582	Belongs to the UPF0302 family
K5K97_RS13340	COG0583	DNA-binding transcription factor activity
K5K97_RS13370	COG0280	phosphate acetyltransferase
K5K97_RS13375	COG3426	butyrate kinase activity
K5K97_RS13385	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K5K97_RS13390	COG1694	Mazg nucleotide pyrophosphohydrolase
K5K97_RS13395	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
K5K97_RS13400	COG0617	tRNA 3'-terminal CCA addition
K5K97_RS13415	COG0488	(ABC) transporter
K5K97_RS13420	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
K5K97_RS13435	COG1272	protein, Hemolysin III
K5K97_RS13440	COG1307	EDD domain protein, DegV family
K5K97_RS13445	COG2755	lipolytic protein G-D-S-L family
K5K97_RS13460	COG4479	Belongs to the UPF0346 family
K5K97_RS13465	COG0793	Belongs to the peptidase S41A family
K5K97_RS13465	COG3409	Peptidoglycan-binding domain 1 protein
K5K97_RS13475	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
K5K97_RS13480	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
K5K97_RS13485	COG0758	DNA mediated transformation
K5K97_RS13490	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
K5K97_RS13495	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
K5K97_RS13500	COG4974	Belongs to the 'phage' integrase family
K5K97_RS13505	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
K5K97_RS13510	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
K5K97_RS13515	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
K5K97_RS13525	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
K5K97_RS13530	COG0735	belongs to the Fur family
K5K97_RS13540	COG1702	phosphate starvation-inducible protein PhoH
K5K97_RS13550	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
K5K97_RS13555	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
K5K97_RS13560	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
K5K97_RS13565	COG1381	Involved in DNA repair and RecF pathway recombination
K5K97_RS13570	COG0752	glycyl-tRNA synthetase alpha subunit
K5K97_RS13575	COG0751	glycine-tRNA ligase activity
K5K97_RS13580	COG0577	efflux transmembrane transporter activity
K5K97_RS13585	COG1136	(ABC) transporter
K5K97_RS13590	COG0515	serine threonine protein kinase
K5K97_RS13595	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
K5K97_RS13600	COG0358	DNA primase activity
K5K97_RS13605	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
K5K97_RS13610	COG2384	SAM-dependent methyltransferase
K5K97_RS13615	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
K5K97_RS13620	COG2195	Cleaves the N-terminal amino acid of tripeptides
K5K97_RS13630	COG0463	Glycosyl transferase, family 2
K5K97_RS13635	COG0456	acetyltransferase
K5K97_RS13640	COG0542	response to heat
K5K97_RS13655	COG0481	GTPase activity
K5K97_RS13715	COG4895	conserved protein (DUF2196)
K5K97_RS13730	COG1472	Belongs to the glycosyl hydrolase 3 family
K5K97_RS13735	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
K5K97_RS13740	COG0768	penicillin binding
K5K97_RS13755	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K5K97_RS13760	COG1136	(ABC) transporter
K5K97_RS13760	COG0577	efflux transmembrane transporter activity
K5K97_RS13760	COG1136	(ABC) transporter
K5K97_RS13760	COG0577	efflux transmembrane transporter activity
K5K97_RS13790	COG3328	transposase activity
K5K97_RS13830	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
K5K97_RS13835	COG4120	Belongs to the binding-protein-dependent transport system permease family
K5K97_RS13855	COG1293	RNA-binding protein homologous to eukaryotic snRNP
K5K97_RS13865	COG0531	amino acid
K5K97_RS13870	COG1278	Cold shock
K5K97_RS13900	COG0284	orotidine-5'-phosphate decarboxylase activity
K5K97_RS13905	COG0167	dihydroorotate dehydrogenase activity
K5K97_RS13910	COG0543	2 iron, 2 sulfur cluster binding
K5K97_RS13915	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
K5K97_RS13920	COG0505	Belongs to the CarA family
K5K97_RS13925	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
K5K97_RS13930	COG0540	Belongs to the ATCase OTCase family
K5K97_RS13935	COG2233	PERMEase
K5K97_RS13945	COG0564	pseudouridine synthase activity
K5K97_RS13950	COG4990	cell redox homeostasis
K5K97_RS13955	COG1516	flagellar protein fliS
K5K97_RS13965	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
K5K97_RS13990	COG1256	bacterial-type flagellum assembly
K5K97_RS13990	COG4786	Flagellar basal body rod
K5K97_RS14005	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
K5K97_RS14005	COG1776	CheC inhibitor of MCP methylation
K5K97_RS14010	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
K5K97_RS14015	COG0835	chemotaxis
K5K97_RS14020	COG2201	protein-glutamate methylesterase activity
K5K97_RS14025	COG1776	CheC inhibitor of MCP methylation
K5K97_RS14030	COG2198	Histidine kinase
K5K97_RS14030	COG0643	Histidine kinase
K5K97_RS14035	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
K5K97_RS14040	COG2201	protein-glutamate methylesterase activity
K5K97_RS14060	COG0577	efflux transmembrane transporter activity
K5K97_RS14060	COG1136	(ABC) transporter
K5K97_RS14160	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K5K97_RS14180	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine