locus-tag	class	description
HZI73_RS00075	COG0588	phosphoglycerate mutase activity
HZI73_RS00105	COG0745	RESPONSE REGULATOR receiver
HZI73_RS00110	COG1278	Cold shock
HZI73_RS00130	COG0697	spore germination
HZI73_RS00150	COG1454	alcohol dehydrogenase
HZI73_RS00155	COG2207	Transcriptional regulator
HZI73_RS00160	COG1671	Belongs to the UPF0178 family
HZI73_RS00170	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HZI73_RS00180	COG0037	tRNA processing
HZI73_RS00185	COG2208	phosphoserine phosphatase activity
HZI73_RS00205	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HZI73_RS00210	COG0776	regulation of translation
HZI73_RS00215	COG3956	TIGRFAM MazG family protein
HZI73_RS00220	COG2002	toxin-antitoxin pair type II binding
HZI73_RS00230	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HZI73_RS00235	COG0193	aminoacyl-tRNA hydrolase activity
HZI73_RS00255	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HZI73_RS00260	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HZI73_RS00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HZI73_RS00270	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HZI73_RS00280	COG1484	DNA-dependent DNA replication
HZI73_RS00315	COG4717	serine-type aminopeptidase activity
HZI73_RS00325	COG0205	6-phosphofructokinase activity
HZI73_RS00345	COG2188	Transcriptional regulator
HZI73_RS00355	COG2226	methyltransferase
HZI73_RS00360	COG0227	Belongs to the bacterial ribosomal protein bL28 family
HZI73_RS00370	COG1363	Peptidase, m42
HZI73_RS00375	COG0668	transmembrane transport
HZI73_RS00385	COG0017	Asparaginyl-tRNA synthetase
HZI73_RS00420	COG1132	(ABC) transporter
HZI73_RS00425	COG1132	(ABC) transporter
HZI73_RS00430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HZI73_RS00490	COG1132	(ABC) transporter
HZI73_RS00495	COG1132	(ABC) transporter
HZI73_RS00520	COG2226	methyltransferase
HZI73_RS00545	COG0519	Catalyzes the synthesis of GMP from XMP
HZI73_RS00570	COG0210	DNA helicase
HZI73_RS00575	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HZI73_RS00610	COG0355	proton-transporting ATP synthase activity, rotational mechanism
HZI73_RS00615	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HZI73_RS00620	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HZI73_RS00625	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HZI73_RS00630	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HZI73_RS00635	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HZI73_RS00665	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HZI73_RS00675	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HZI73_RS00685	COG0698	ribose 5-phosphate isomerase
HZI73_RS00690	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HZI73_RS00695	COG0009	L-threonylcarbamoyladenylate synthase
HZI73_RS00705	COG0860	N-Acetylmuramoyl-L-alanine amidase
HZI73_RS00720	COG2199	diguanylate cyclase activity
HZI73_RS00720	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
HZI73_RS00735	COG0631	protein serine/threonine phosphatase activity
HZI73_RS00785	COG0305	Participates in initiation and elongation during chromosome replication
HZI73_RS00790	COG0359	binds to the 23S rRNA
HZI73_RS00795	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
HZI73_RS00810	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HZI73_RS00815	COG0629	single-stranded DNA binding
HZI73_RS00820	COG0360	Binds together with S18 to 16S ribosomal RNA
HZI73_RS00825	COG4481	Protein conserved in bacteria
HZI73_RS00915	COG3949	Membrane
HZI73_RS00920	COG0297	glycogen (starch) synthase activity
HZI73_RS00930	COG1733	regulation of RNA biosynthetic process
HZI73_RS00935	COG1164	Oligoendopeptidase f
HZI73_RS00940	COG4806	L-rhamnose isomerase
HZI73_RS00945	COG1070	Carbohydrate kinase
HZI73_RS00955	COG2207	Transcriptional regulator
HZI73_RS00975	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HZI73_RS00990	COG1501	Belongs to the glycosyl hydrolase 31 family
HZI73_RS01000	COG0395	ABC-type sugar transport system, permease component
HZI73_RS01005	COG1175	transmembrane transport
HZI73_RS01010	COG1609	Transcriptional regulator
HZI73_RS01040	COG1489	DNA binding
HZI73_RS01065	COG2972	Histidine kinase
HZI73_RS01075	COG0395	ABC-type sugar transport system, permease component
HZI73_RS01080	COG4209	transmembrane transport
HZI73_RS01090	COG0745	RESPONSE REGULATOR receiver
HZI73_RS01095	COG5002	protein histidine kinase activity
HZI73_RS01105	COG1131	(ABC) transporter
HZI73_RS01115	COG0840	transmembrane signaling receptor activity
HZI73_RS01135	COG1595	DNA-templated transcription, initiation
HZI73_RS01150	COG1827	regulation of RNA biosynthetic process
HZI73_RS01155	COG0166	Belongs to the GPI family
HZI73_RS01160	COG0726	polysaccharide deacetylase
HZI73_RS01200	COG3852	Histidine kinase
HZI73_RS01220	COG0596	Alpha beta hydrolase
HZI73_RS01220	COG2945	thiolester hydrolase activity
HZI73_RS01235	COG0825	malonyl-CoA metabolic process
HZI73_RS01240	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HZI73_RS01245	COG0439	Biotin carboxylase
HZI73_RS01255	COG0511	ligase activity, forming carbon-carbon bonds
HZI73_RS01260	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HZI73_RS01270	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HZI73_RS01275	COG2070	2-Nitropropane dioxygenase
HZI73_RS01285	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HZI73_RS01290	COG1695	Transcriptional regulator
HZI73_RS01305	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HZI73_RS01315	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HZI73_RS01320	COG0084	hydrolase, TatD family'
HZI73_RS01325	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HZI73_RS01325	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HZI73_RS01340	COG0395	ABC-type sugar transport system, permease component
HZI73_RS01345	COG4209	transmembrane transport
HZI73_RS01355	COG2207	Transcriptional regulator
HZI73_RS01360	COG3119	arylsulfatase activity
HZI73_RS01365	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HZI73_RS01370	COG0673	inositol 2-dehydrogenase activity
HZI73_RS01390	COG3119	arylsulfatase activity
HZI73_RS01395	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HZI73_RS01400	COG1882	Formate acetyltransferase
HZI73_RS01410	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HZI73_RS01470	COG3119	arylsulfatase activity
HZI73_RS01500	COG1217	gtp-binding protein TYPA
HZI73_RS01515	COG1846	Transcriptional regulator
HZI73_RS01525	COG2715	membrane protein required for spore maturation
HZI73_RS01540	COG1131	(ABC) transporter
HZI73_RS01555	COG1760	l-serine dehydratase
HZI73_RS01560	COG1760	l-serine dehydratase
HZI73_RS01565	COG2002	toxin-antitoxin pair type II binding
HZI73_RS01570	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HZI73_RS01575	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
HZI73_RS01580	COG1774	PSP1 C-terminal conserved region
HZI73_RS01585	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HZI73_RS01595	COG3870	Protein conserved in bacteria
HZI73_RS01600	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HZI73_RS01605	COG1982	Orn Lys Arg decarboxylase major
HZI73_RS01665	COG1079	Belongs to the binding-protein-dependent transport system permease family
HZI73_RS01670	COG4603	Belongs to the binding-protein-dependent transport system permease family
HZI73_RS01675	COG3845	ABC transporter
HZI73_RS01680	COG1744	ABC transporter substrate-binding protein PnrA-like
HZI73_RS01705	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HZI73_RS01710	COG0187	DNA topoisomerase II activity
HZI73_RS01715	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HZI73_RS01730	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HZI73_RS01735	COG0230	Belongs to the bacterial ribosomal protein bL34 family
HZI73_RS01740	COG0594	ribonuclease P activity
HZI73_RS01745	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
HZI73_RS01755	COG1847	R3H domain protein
HZI73_RS01760	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HZI73_RS01765	COG0445	tRNA wobble uridine modification
HZI73_RS01770	COG0357	Ribosomal RNA small subunit methyltransferase G
HZI73_RS01785	COG0697	spore germination
HZI73_RS01800	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HZI73_RS01810	COG0157	Belongs to the NadC ModD family
HZI73_RS01830	COG0018	arginyl-trna synthetase
HZI73_RS01835	COG1192	Involved in chromosome partitioning
HZI73_RS01840	COG1475	DNA binding
HZI73_RS01855	COG0561	phosphatase activity
HZI73_RS01860	COG1454	alcohol dehydrogenase
HZI73_RS01860	COG1012	belongs to the aldehyde dehydrogenase family
HZI73_RS01870	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HZI73_RS01880	COG2873	o-acetylhomoserine
HZI73_RS01890	COG2234	aminopeptidase activity
HZI73_RS01895	COG4294	response to UV
HZI73_RS01900	COG1533	DNA photolyase activity
HZI73_RS01905	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HZI73_RS01910	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HZI73_RS01940	COG3033	Beta-eliminating lyase
HZI73_RS01945	COG2340	Cysteine-rich secretory protein family
HZI73_RS01950	COG2015	COG2015, Alkyl sulfatase and related hydrolases
HZI73_RS01960	COG0745	RESPONSE REGULATOR receiver
HZI73_RS01965	COG5002	protein histidine kinase activity
HZI73_RS01970	COG1136	(ABC) transporter
HZI73_RS02000	COG3153	acetyltransferase
HZI73_RS02010	COG0469	pyruvate kinase activity
HZI73_RS02040	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
HZI73_RS02045	COG0220	tRNA (guanine-N7-)-methyltransferase activity
HZI73_RS02070	COG3118	belongs to the thioredoxin family
HZI73_RS02075	COG0628	permease
HZI73_RS02080	COG0840	transmembrane signaling receptor activity
HZI73_RS02085	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HZI73_RS02090	COG1309	transcriptional regulator
HZI73_RS02100	COG1349	DNA-binding transcription factor activity
HZI73_RS02125	COG1129	ABC transporter
HZI73_RS02130	COG1172	Belongs to the binding-protein-dependent transport system permease family
HZI73_RS02135	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HZI73_RS02145	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HZI73_RS02155	COG0183	Belongs to the thiolase family
HZI73_RS02165	COG0673	inositol 2-dehydrogenase activity
HZI73_RS02170	COG1435	thymidine kinase activity
HZI73_RS02180	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HZI73_RS02190	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HZI73_RS02205	COG1695	Transcriptional regulator
HZI73_RS02215	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
HZI73_RS02220	COG5658	integral membrane protein
HZI73_RS02225	COG1609	Transcriptional regulator
HZI73_RS02235	COG1175	transmembrane transport
HZI73_RS02240	COG3833	ABC-type maltose transport systems, permease component
HZI73_RS02245	COG0366	Alpha amylase catalytic
HZI73_RS02250	COG0366	Alpha amylase catalytic
HZI73_RS02255	COG1609	Transcriptional regulator
HZI73_RS02270	COG1175	transmembrane transport
HZI73_RS02275	COG0395	ABC-type sugar transport system, permease component
HZI73_RS02295	COG1175	transmembrane transport
HZI73_RS02300	COG3833	ABC-type maltose transport systems, permease component
HZI73_RS02305	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
HZI73_RS02320	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HZI73_RS02335	COG0674	pyruvate-flavodoxin oxidoreductase activity
HZI73_RS02345	COG3250	beta-galactosidase activity
HZI73_RS02350	COG0488	(ABC) transporter
HZI73_RS02365	COG0347	Belongs to the P(II) protein family
HZI73_RS02370	COG0004	ammonium transporteR
HZI73_RS02375	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HZI73_RS02390	COG1191	sigma factor activity
HZI73_RS02400	COG2373	Large extracellular alpha-helical protein
HZI73_RS02405	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HZI73_RS02420	COG0697	spore germination
HZI73_RS02435	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
HZI73_RS02440	COG2972	Histidine kinase
HZI73_RS02445	COG2207	Transcriptional regulator
HZI73_RS02445	COG4753	response regulator
HZI73_RS02455	COG1175	transmembrane transport
HZI73_RS02460	COG0395	ABC-type sugar transport system, permease component
HZI73_RS02465	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HZI73_RS02505	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HZI73_RS02520	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HZI73_RS02555	COG1136	(ABC) transporter
HZI73_RS02560	COG1136	(ABC) transporter
HZI73_RS02560	COG0577	efflux transmembrane transporter activity
HZI73_RS02570	COG5002	protein histidine kinase activity
HZI73_RS02570	COG3850	Histidine kinase
HZI73_RS02610	COG0124	histidyl-tRNA synthetase
HZI73_RS02620	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HZI73_RS02650	COG2221	Nitrite and sulphite reductase 4Fe-4S
HZI73_RS02655	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HZI73_RS02665	COG2188	Transcriptional regulator
HZI73_RS02680	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
HZI73_RS02685	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HZI73_RS02700	COG2373	Large extracellular alpha-helical protein
HZI73_RS02750	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HZI73_RS02760	COG0674	pyruvate-flavodoxin oxidoreductase activity
HZI73_RS02765	COG1013	pyruvate-flavodoxin oxidoreductase activity
HZI73_RS02770	COG0457	Tetratricopeptide repeat
HZI73_RS02770	COG0705	Rhomboid family
HZI73_RS02795	COG3852	Histidine kinase
HZI73_RS02800	COG0537	adenosine 5'-monophosphoramidase activity
HZI73_RS02805	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HZI73_RS02810	COG1609	Transcriptional regulator
HZI73_RS02820	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HZI73_RS02825	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HZI73_RS02830	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
HZI73_RS02840	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HZI73_RS02880	COG0739	heme binding
HZI73_RS02885	COG0745	RESPONSE REGULATOR receiver
HZI73_RS02890	COG5002	protein histidine kinase activity
HZI73_RS02950	COG3850	Histidine kinase
HZI73_RS02950	COG5002	protein histidine kinase activity
HZI73_RS02965	COG1595	DNA-templated transcription, initiation
HZI73_RS03030	COG0697	spore germination
HZI73_RS03040	COG1028	Short-chain dehydrogenase reductase Sdr
HZI73_RS03075	COG1309	transcriptional regulator
HZI73_RS03115	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HZI73_RS03120	COG0745	RESPONSE REGULATOR receiver
HZI73_RS03125	COG0628	permease
HZI73_RS03150	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HZI73_RS03170	COG0463	Glycosyl transferase, family 2
HZI73_RS03175	COG2246	polysaccharide biosynthetic process
HZI73_RS03195	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HZI73_RS03200	COG0463	Glycosyl transferase, family 2
HZI73_RS03220	COG1131	(ABC) transporter
HZI73_RS03240	COG0251	oxidation-reduction process
HZI73_RS03245	COG3681	Belongs to the UPF0597 family
HZI73_RS03255	COG4555	ABC transporter
HZI73_RS03265	COG1482	cell wall glycoprotein biosynthetic process
HZI73_RS03270	COG0617	tRNA 3'-terminal CCA addition
HZI73_RS03315	COG3842	ATPase activity
HZI73_RS03330	COG2972	Histidine kinase
HZI73_RS03335	COG2207	Transcriptional regulator
HZI73_RS03335	COG4753	response regulator
HZI73_RS03340	COG1309	transcriptional regulator
HZI73_RS03345	COG0574	Belongs to the PEP-utilizing enzyme family
HZI73_RS03345	COG3848	Pyruvate phosphate dikinase
HZI73_RS03350	COG1309	transcriptional regulator
HZI73_RS03355	COG1309	transcriptional regulator
HZI73_RS03390	COG0436	Aminotransferase
HZI73_RS03405	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HZI73_RS03415	COG4466	Protein conserved in bacteria
HZI73_RS03425	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HZI73_RS03430	COG1802	Transcriptional regulator
HZI73_RS03445	COG0697	spore germination
HZI73_RS03475	COG1181	Belongs to the D-alanine--D-alanine ligase family
HZI73_RS03490	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HZI73_RS03500	COG3290	protein histidine kinase activity
HZI73_RS03520	COG0793	Belongs to the peptidase S41A family
HZI73_RS03525	COG0504	CTP synthase activity
HZI73_RS03545	COG1640	4-alpha-glucanotransferase
HZI73_RS03560	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HZI73_RS03570	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HZI73_RS03575	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HZI73_RS03590	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HZI73_RS03600	COG0058	SHG alpha-glucan phosphorylase activity
HZI73_RS03605	COG2972	Histidine kinase
HZI73_RS03610	COG2207	Transcriptional regulator
HZI73_RS03610	COG4753	response regulator
HZI73_RS03615	COG1175	transmembrane transport
HZI73_RS03620	COG0395	ABC-type sugar transport system, permease component
HZI73_RS03635	COG2385	sporulation resulting in formation of a cellular spore
HZI73_RS03650	COG1720	tRNA m6t6A37 methyltransferase activity
HZI73_RS03660	COG2207	Transcriptional regulator
HZI73_RS03660	COG3708	Transcriptional regulator
HZI73_RS03670	COG1609	Transcriptional regulator
HZI73_RS03675	COG1077	Cell shape determining protein MreB Mrl
HZI73_RS03680	COG4786	Flagellar basal body rod
HZI73_RS03705	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HZI73_RS03710	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HZI73_RS03715	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HZI73_RS03730	COG3418	PFAM FlgN family protein
HZI73_RS03735	COG1256	bacterial-type flagellum assembly
HZI73_RS03735	COG4786	Flagellar basal body rod
HZI73_RS03745	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HZI73_RS03750	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
HZI73_RS03755	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HZI73_RS03770	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HZI73_RS03775	COG1516	flagellar protein fliS
HZI73_RS03795	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HZI73_RS03805	COG0250	Participates in transcription elongation, termination and antitermination
HZI73_RS03810	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HZI73_RS03815	COG0081	regulation of translation
HZI73_RS03825	COG0222	ribosome binding
HZI73_RS03830	COG0085	RNA polymerase activity
HZI73_RS03835	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HZI73_RS03840	COG1358	cellular component organization or biogenesis
HZI73_RS03845	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HZI73_RS03850	COG0049	tRNA binding
HZI73_RS03855	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HZI73_RS03860	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HZI73_RS03865	COG0051	transcription antitermination factor activity, RNA binding
HZI73_RS03870	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HZI73_RS03885	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HZI73_RS03895	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HZI73_RS03905	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HZI73_RS03910	COG0255	Belongs to the universal ribosomal protein uL29 family
HZI73_RS03915	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HZI73_RS03930	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HZI73_RS03935	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HZI73_RS03940	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HZI73_RS03945	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HZI73_RS03950	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HZI73_RS03955	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HZI73_RS03960	COG1841	ribosomal large subunit assembly
HZI73_RS03965	COG0200	Binds to the 23S rRNA
HZI73_RS03970	COG0201	protein transport
HZI73_RS03975	COG0563	adenylate kinase activity
HZI73_RS03990	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HZI73_RS03995	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HZI73_RS04000	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HZI73_RS04005	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HZI73_RS04010	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HZI73_RS04015	COG0202	RNA polymerase activity
HZI73_RS04020	COG0203	ribosomal protein L17
HZI73_RS04035	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HZI73_RS04050	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HZI73_RS04055	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
HZI73_RS04085	COG0840	transmembrane signaling receptor activity
HZI73_RS04100	COG1773	rubredoxin
HZI73_RS04105	COG1609	Transcriptional regulator
HZI73_RS04110	COG0673	inositol 2-dehydrogenase activity
HZI73_RS04115	COG1082	Xylose isomerase domain protein TIM barrel
HZI73_RS04120	COG0673	inositol 2-dehydrogenase activity
HZI73_RS04130	COG0840	transmembrane signaling receptor activity
HZI73_RS04140	COG1131	(ABC) transporter
HZI73_RS04145	COG1725	Transcriptional regulator
HZI73_RS04155	COG0426	domain, Protein
HZI73_RS04160	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HZI73_RS04165	COG0569	domain protein
HZI73_RS04170	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HZI73_RS04190	COG1368	sulfuric ester hydrolase activity
HZI73_RS04195	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HZI73_RS04200	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HZI73_RS04225	COG3437	response regulator, receiver
HZI73_RS04230	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HZI73_RS04255	COG4152	abc transporter atp-binding protein
HZI73_RS04260	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
HZI73_RS04260	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
HZI73_RS04280	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HZI73_RS04285	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HZI73_RS04295	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HZI73_RS04300	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HZI73_RS04380	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HZI73_RS04390	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HZI73_RS04430	COG4977	sequence-specific DNA binding
HZI73_RS04460	COG1309	transcriptional regulator
HZI73_RS04495	COG2972	Histidine kinase
HZI73_RS04500	COG2207	Transcriptional regulator
HZI73_RS04500	COG4753	response regulator
HZI73_RS04510	COG4209	transmembrane transport
HZI73_RS04515	COG0395	ABC-type sugar transport system, permease component
HZI73_RS04525	COG3250	beta-galactosidase activity
HZI73_RS04535	COG3250	beta-galactosidase activity
HZI73_RS04540	COG3119	arylsulfatase activity
HZI73_RS04545	COG4443	Transcriptional Coactivator p15 (PC4)
HZI73_RS04550	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HZI73_RS04565	COG0494	nUDIX hydrolase
HZI73_RS04575	COG2186	Transcriptional regulator
HZI73_RS04585	COG0840	transmembrane signaling receptor activity
HZI73_RS04600	COG0640	Transcriptional regulator
HZI73_RS04605	COG0798	PFAM Bile acid sodium symporter
HZI73_RS04615	COG2207	Transcriptional regulator
HZI73_RS04630	COG4209	transmembrane transport
HZI73_RS04635	COG0395	ABC-type sugar transport system, permease component
HZI73_RS04640	COG1472	Belongs to the glycosyl hydrolase 3 family
HZI73_RS04690	COG0577	efflux transmembrane transporter activity
HZI73_RS04690	COG1136	(ABC) transporter
HZI73_RS04700	COG0577	efflux transmembrane transporter activity
HZI73_RS04700	COG1136	(ABC) transporter
HZI73_RS04715	COG1151	hydroxylamine reductase activity
HZI73_RS04730	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HZI73_RS04735	COG1501	Belongs to the glycosyl hydrolase 31 family
HZI73_RS04740	COG1609	Transcriptional regulator
HZI73_RS04745	COG2602	Beta-lactamase
HZI73_RS04755	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HZI73_RS04760	COG3275	phosphorelay sensor kinase activity
HZI73_RS04765	COG2207	Transcriptional regulator
HZI73_RS04765	COG4753	response regulator
HZI73_RS04770	COG4209	transmembrane transport
HZI73_RS04775	COG0395	ABC-type sugar transport system, permease component
HZI73_RS04785	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
HZI73_RS04795	COG2755	lipolytic protein G-D-S-L family
HZI73_RS04795	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
HZI73_RS04810	COG1595	DNA-templated transcription, initiation
HZI73_RS04895	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HZI73_RS04905	COG2226	methyltransferase
HZI73_RS04915	COG3708	Transcriptional regulator
HZI73_RS04915	COG2207	Transcriptional regulator
HZI73_RS04925	COG5002	protein histidine kinase activity
HZI73_RS04970	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HZI73_RS04975	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HZI73_RS05005	COG1842	Phage shock protein A
HZI73_RS05020	COG1349	DNA-binding transcription factor activity
HZI73_RS05045	COG1166	arginine decarboxylase activity
HZI73_RS05050	COG0010	Belongs to the arginase family
HZI73_RS05070	COG2339	peptidase activity
HZI73_RS05085	COG1940	carbohydrate kinase activity
HZI73_RS05100	COG0622	Phosphoesterase
HZI73_RS05110	COG0116	Belongs to the methyltransferase superfamily
HZI73_RS05135	COG1252	NADH dehydrogenase
HZI73_RS05150	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HZI73_RS05155	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
HZI73_RS05160	COG0163	prenyltransferase activity
HZI73_RS05165	COG1116	anion transmembrane transporter activity
HZI73_RS05170	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HZI73_RS05175	COG3976	FMN-binding domain protein
HZI73_RS05175	COG1053	succinate dehydrogenase
HZI73_RS05180	COG3290	protein histidine kinase activity
HZI73_RS05195	COG0860	N-Acetylmuramoyl-L-alanine amidase
HZI73_RS05200	COG0860	N-Acetylmuramoyl-L-alanine amidase
HZI73_RS05210	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HZI73_RS05215	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HZI73_RS05260	COG2954	triphosphatase activity
HZI73_RS05270	COG4166	transmembrane transport
HZI73_RS05275	COG0601	transmembrane transport
HZI73_RS05280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HZI73_RS05285	COG0444	Belongs to the ABC transporter superfamily
HZI73_RS05290	COG4608	Belongs to the ABC transporter superfamily
HZI73_RS05330	COG0544	peptidyl-prolyl cis-trans isomerase activity
HZI73_RS05335	COG0740	serine-type endopeptidase activity
HZI73_RS05340	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HZI73_RS05345	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HZI73_RS05350	COG0218	Necessary for normal cell division and for the maintenance of normal septation
HZI73_RS05360	COG1242	4 iron, 4 sulfur cluster binding
HZI73_RS05370	COG5658	integral membrane protein
HZI73_RS05375	COG0640	Transcriptional regulator
HZI73_RS05380	COG0281	malic enzyme
HZI73_RS05385	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HZI73_RS05420	COG0789	Transcriptional regulator
HZI73_RS05425	COG0745	RESPONSE REGULATOR receiver
HZI73_RS05425	COG2972	Histidine kinase
HZI73_RS05430	COG3279	Response regulator of the LytR AlgR family
HZI73_RS05445	COG1309	transcriptional regulator
HZI73_RS05455	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
HZI73_RS05460	COG1609	Transcriptional regulator
HZI73_RS05470	COG1472	Belongs to the glycosyl hydrolase 3 family
HZI73_RS05480	COG1175	transmembrane transport
HZI73_RS05485	COG0395	ABC-type sugar transport system, permease component
HZI73_RS05490	COG1605	Chorismate mutase
HZI73_RS05490	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
HZI73_RS05510	COG0842	Transport permease protein
HZI73_RS05520	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HZI73_RS05525	COG1120	ATPase activity
HZI73_RS05530	COG1797	cobyrinic acid a,c-diamide synthase activity
HZI73_RS05550	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
HZI73_RS05585	COG2207	Transcriptional regulator
HZI73_RS05585	COG3708	Transcriptional regulator
HZI73_RS05620	COG5002	protein histidine kinase activity
HZI73_RS05625	COG0577	efflux transmembrane transporter activity
HZI73_RS05625	COG1136	(ABC) transporter
HZI73_RS05630	COG0577	efflux transmembrane transporter activity
HZI73_RS05665	COG3177	Filamentation induced by cAMP protein fic
HZI73_RS05695	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HZI73_RS05705	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
HZI73_RS05710	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HZI73_RS05715	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HZI73_RS05720	COG1794	racemase activity, acting on amino acids and derivatives
HZI73_RS05725	COG1968	undecaprenyl-diphosphatase activity
HZI73_RS05730	COG0250	Participates in transcription elongation, termination and antitermination
HZI73_RS05735	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
HZI73_RS05735	COG1605	Chorismate mutase
HZI73_RS05765	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HZI73_RS05770	COG2192	nodulation
HZI73_RS05830	COG1819	glycosyl
HZI73_RS05885	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HZI73_RS05895	COG1032	radical SAM domain protein
HZI73_RS05905	COG0574	Belongs to the PEP-utilizing enzyme family
HZI73_RS05905	COG3848	Pyruvate phosphate dikinase
HZI73_RS05915	COG1032	radical SAM domain protein
HZI73_RS05920	COG1032	radical SAM domain protein
HZI73_RS05950	COG1028	Short-chain dehydrogenase reductase Sdr
HZI73_RS05955	COG2199	diguanylate cyclase activity
HZI73_RS05970	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HZI73_RS05980	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HZI73_RS06005	COG0183	Belongs to the thiolase family
HZI73_RS06010	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HZI73_RS06015	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HZI73_RS06040	COG1309	transcriptional regulator
HZI73_RS06050	COG0701	Predicted permease
HZI73_RS06055	COG0640	Transcriptional regulator
HZI73_RS06060	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HZI73_RS06065	COG4807	Protein conserved in bacteria
HZI73_RS06080	COG2207	Transcriptional regulator
HZI73_RS06090	COG1960	acyl-CoA dehydrogenase activity
HZI73_RS06095	COG2086	electron transfer activity
HZI73_RS06100	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
HZI73_RS06110	COG2192	nodulation
HZI73_RS06115	COG2192	nodulation
HZI73_RS06120	COG1250	3-hydroxyacyl-CoA dehydrogenase
HZI73_RS06150	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HZI73_RS06150	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HZI73_RS06150	COG1028	Short-chain dehydrogenase reductase Sdr
HZI73_RS06150	COG3321	synthase
HZI73_RS06150	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HZI73_RS06155	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HZI73_RS06160	COG1132	(ABC) transporter
HZI73_RS06165	COG1132	(ABC) transporter
HZI73_RS06220	COG1307	EDD domain protein, DegV family
HZI73_RS06240	COG2239	Acts as a magnesium transporter
HZI73_RS06250	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HZI73_RS06255	COG0254	rRNA binding
HZI73_RS06260	COG3872	metal-dependent enzyme
HZI73_RS06270	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HZI73_RS06275	COG0475	glutathione-regulated potassium exporter activity
HZI73_RS06290	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HZI73_RS06295	COG0284	orotidine-5'-phosphate decarboxylase activity
HZI73_RS06315	COG0543	2 iron, 2 sulfur cluster binding
HZI73_RS06320	COG0167	dihydroorotate dehydrogenase activity
HZI73_RS06325	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HZI73_RS06335	COG3290	protein histidine kinase activity
HZI73_RS06345	COG4864	UPF0365 protein
HZI73_RS06350	COG3279	Response regulator of the LytR AlgR family
HZI73_RS06370	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HZI73_RS06375	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HZI73_RS06380	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
HZI73_RS06385	COG0189	ligase activity
HZI73_RS06395	COG0489	protein tyrosine kinase activity
HZI73_RS06450	COG0525	valine-tRNA ligase activity
HZI73_RS06455	COG0285	dihydrofolate synthase activity
HZI73_RS06485	COG2172	sigma factor antagonist activity
HZI73_RS06490	COG1191	sigma factor activity
HZI73_RS06520	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HZI73_RS06525	COG1418	mRNA catabolic process
HZI73_RS06545	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HZI73_RS06550	COG0436	Aminotransferase
HZI73_RS06565	COG5012	cobalamin binding
HZI73_RS06570	COG5012	cobalamin binding
HZI73_RS06575	COG2207	Transcriptional regulator
HZI73_RS06585	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HZI73_RS06585	COG2207	Transcriptional regulator
HZI73_RS06590	COG2201	protein-glutamate methylesterase activity
HZI73_RS06600	COG1653	transport
HZI73_RS06605	COG1175	transmembrane transport
HZI73_RS06610	COG0395	ABC-type sugar transport system, permease component
HZI73_RS06640	COG0095	Lipoate-protein ligase
HZI73_RS06645	COG1739	Uncharacterized protein family UPF0029
HZI73_RS06655	COG0745	RESPONSE REGULATOR receiver
HZI73_RS06660	COG5002	protein histidine kinase activity
HZI73_RS06660	COG3850	Histidine kinase
HZI73_RS06665	COG2033	superoxide reductase activity
HZI73_RS06700	COG2957	Belongs to the agmatine deiminase family
HZI73_RS06705	COG0726	polysaccharide deacetylase
HZI73_RS06730	COG3383	formate dehydrogenase (NAD+) activity
HZI73_RS06735	COG0746	molybdenum cofactor guanylyltransferase activity
HZI73_RS06740	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HZI73_RS06745	COG1396	sequence-specific DNA binding
HZI73_RS06765	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
HZI73_RS06780	COG1321	iron dependent repressor
HZI73_RS06785	COG4106	trans-aconitate 2-methyltransferase activity
HZI73_RS06790	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
HZI73_RS06795	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HZI73_RS06815	COG1362	aminopeptidase activity
HZI73_RS06825	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HZI73_RS06835	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HZI73_RS06855	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
HZI73_RS06870	COG1116	anion transmembrane transporter activity
HZI73_RS06885	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HZI73_RS06900	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
HZI73_RS06905	COG4496	protein, YerC YecD
HZI73_RS06925	COG0210	DNA helicase
HZI73_RS06980	COG3344	reverse transcriptase
HZI73_RS07025	COG1971	Probably functions as a manganese efflux pump
HZI73_RS07055	COG4978	Transcriptional regulator
HZI73_RS07055	COG0789	Transcriptional regulator
HZI73_RS07060	COG2267	carboxylic ester hydrolase activity
HZI73_RS07070	COG1472	Belongs to the glycosyl hydrolase 3 family
HZI73_RS07080	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
HZI73_RS07090	COG1653	transport
HZI73_RS07095	COG4209	transmembrane transport
HZI73_RS07100	COG0395	ABC-type sugar transport system, permease component
HZI73_RS07125	COG1472	Belongs to the glycosyl hydrolase 3 family
HZI73_RS07155	COG0129	dihydroxy-acid dehydratase activity
HZI73_RS07170	COG1744	ABC transporter substrate-binding protein PnrA-like
HZI73_RS07175	COG3845	ABC transporter
HZI73_RS07180	COG4603	Belongs to the binding-protein-dependent transport system permease family
HZI73_RS07185	COG1079	Belongs to the binding-protein-dependent transport system permease family
HZI73_RS07195	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HZI73_RS07195	COG3933	PFAM sigma-54 factor interaction domain-containing protein
HZI73_RS07200	COG1447	Phosphotransferase system cellobiose-specific component IIA
HZI73_RS07205	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HZI73_RS07205	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HZI73_RS07210	COG3119	arylsulfatase activity
HZI73_RS07215	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HZI73_RS07225	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HZI73_RS07265	COG2249	NAD(P)H dehydrogenase (quinone) activity
HZI73_RS07275	COG3119	arylsulfatase activity
HZI73_RS07280	COG4209	transmembrane transport
HZI73_RS07285	COG0395	ABC-type sugar transport system, permease component
HZI73_RS07290	COG1653	transport
HZI73_RS07300	COG4753	response regulator
HZI73_RS07300	COG2207	Transcriptional regulator
HZI73_RS07310	COG3408	Glycogen debranching enzyme
HZI73_RS07310	COG3119	arylsulfatase activity
HZI73_RS07325	COG3250	beta-galactosidase activity
HZI73_RS07330	COG4209	transmembrane transport
HZI73_RS07335	COG0395	ABC-type sugar transport system, permease component
HZI73_RS07340	COG1653	transport
HZI73_RS07355	COG3119	arylsulfatase activity
HZI73_RS07360	COG1472	Belongs to the glycosyl hydrolase 3 family
HZI73_RS07370	COG3279	Response regulator of the LytR AlgR family
HZI73_RS07385	COG3119	arylsulfatase activity
HZI73_RS07390	COG3119	arylsulfatase activity
HZI73_RS07390	COG3408	Glycogen debranching enzyme
HZI73_RS07395	COG3708	Transcriptional regulator
HZI73_RS07395	COG2207	Transcriptional regulator
HZI73_RS07400	COG4209	transmembrane transport
HZI73_RS07405	COG0395	ABC-type sugar transport system, permease component
HZI73_RS07410	COG3250	beta-galactosidase activity
HZI73_RS07430	COG0584	glycerophosphoryl diester phosphodiesterase
HZI73_RS07445	COG1609	Transcriptional regulator
HZI73_RS07450	COG1070	Carbohydrate kinase
HZI73_RS07455	COG0667	Aldo Keto reductase
HZI73_RS07460	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HZI73_RS07465	COG2972	Histidine kinase
HZI73_RS07470	COG4753	response regulator
HZI73_RS07470	COG2207	Transcriptional regulator
HZI73_RS07495	COG0366	Alpha amylase catalytic
HZI73_RS07520	COG2255	four-way junction helicase activity
HZI73_RS07540	COG1846	Transcriptional regulator
HZI73_RS07550	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HZI73_RS07555	COG0095	Lipoate-protein ligase
HZI73_RS07565	COG2972	Histidine kinase
HZI73_RS07570	COG4753	response regulator
HZI73_RS07570	COG2207	Transcriptional regulator
HZI73_RS07595	COG1609	Transcriptional regulator
HZI73_RS07605	COG1175	transmembrane transport
HZI73_RS07610	COG0395	ABC-type sugar transport system, permease component
HZI73_RS07615	COG1554	hydrolase, family 65, central catalytic
HZI73_RS07625	COG4977	sequence-specific DNA binding
HZI73_RS07635	COG1312	Catalyzes the dehydration of D-mannonate
HZI73_RS07640	COG0006	proline dipeptidase activity
HZI73_RS07645	COG1028	Short-chain dehydrogenase reductase Sdr
HZI73_RS07650	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HZI73_RS07650	COG0473	3-isopropylmalate dehydrogenase activity
HZI73_RS07660	COG3708	Transcriptional regulator
HZI73_RS07660	COG2207	Transcriptional regulator
HZI73_RS07695	COG1129	ABC transporter
HZI73_RS07705	COG1879	ABC-type sugar transport system periplasmic component
HZI73_RS07710	COG2972	Histidine kinase
HZI73_RS07710	COG0745	RESPONSE REGULATOR receiver
HZI73_RS07715	COG2207	Transcriptional regulator
HZI73_RS07735	COG0747	negative chemotaxis
HZI73_RS07745	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HZI73_RS07750	COG0444	Belongs to the ABC transporter superfamily
HZI73_RS07755	COG4608	Belongs to the ABC transporter superfamily
HZI73_RS07765	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HZI73_RS07770	COG1917	Cupin 2, conserved barrel domain protein
HZI73_RS07770	COG4977	sequence-specific DNA binding
HZI73_RS07775	COG0549	Belongs to the carbamate kinase family
HZI73_RS07790	COG1653	transport
HZI73_RS07795	COG4209	transmembrane transport
HZI73_RS07800	COG0395	ABC-type sugar transport system, permease component
HZI73_RS07815	COG1917	Cupin 2, conserved barrel domain protein
HZI73_RS07825	COG2972	Histidine kinase
HZI73_RS07830	COG2207	Transcriptional regulator
HZI73_RS07830	COG4753	response regulator
HZI73_RS07840	COG0395	ABC-type sugar transport system, permease component
HZI73_RS07845	COG1653	transport
HZI73_RS07855	COG2188	Transcriptional regulator
HZI73_RS07865	COG4209	transmembrane transport
HZI73_RS07870	COG0395	ABC-type sugar transport system, permease component
HZI73_RS07875	COG1653	transport
HZI73_RS07880	COG2207	Transcriptional regulator
HZI73_RS07910	COG4948	Mandelate Racemase Muconate Lactonizing
HZI73_RS07915	COG1012	belongs to the aldehyde dehydrogenase family
HZI73_RS07920	COG0800	Aldolase
HZI73_RS07930	COG3250	beta-galactosidase activity
HZI73_RS07955	COG1501	Belongs to the glycosyl hydrolase 31 family
HZI73_RS07970	COG3119	arylsulfatase activity
HZI73_RS07980	COG1653	transport
HZI73_RS07990	COG4209	transmembrane transport
HZI73_RS07995	COG0395	ABC-type sugar transport system, permease component
HZI73_RS08010	COG2207	Transcriptional regulator
HZI73_RS08020	COG3119	arylsulfatase activity
HZI73_RS08035	COG4209	transmembrane transport
HZI73_RS08040	COG0395	ABC-type sugar transport system, permease component
HZI73_RS08045	COG3119	arylsulfatase activity
HZI73_RS08050	COG5434	Belongs to the glycosyl hydrolase 28 family
HZI73_RS08055	COG3119	arylsulfatase activity
HZI73_RS08060	COG3250	beta-galactosidase activity
HZI73_RS08065	COG3119	arylsulfatase activity
HZI73_RS08070	COG3119	arylsulfatase activity
HZI73_RS08115	COG1082	Xylose isomerase domain protein TIM barrel
HZI73_RS08125	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HZI73_RS08135	COG2186	Transcriptional regulator
HZI73_RS08140	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HZI73_RS08145	COG2186	Transcriptional regulator
HZI73_RS08155	COG0149	triose-phosphate isomerase activity
HZI73_RS08165	COG0310	cobalt ion transport
HZI73_RS08175	COG1122	ATPase activity
HZI73_RS08180	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
HZI73_RS08185	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HZI73_RS08190	COG1691	(AIR) carboxylase
HZI73_RS08205	COG1346	cytolysis
HZI73_RS08220	COG2376	Dihydroxyacetone kinase
HZI73_RS08230	COG3973	AAA domain
HZI73_RS08235	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HZI73_RS08275	COG1175	transmembrane transport
HZI73_RS08280	COG0395	ABC-type sugar transport system, permease component
HZI73_RS08300	COG1175	transmembrane transport
HZI73_RS08305	COG3833	ABC-type maltose transport systems, permease component
HZI73_RS08310	COG3420	alginic acid biosynthetic process
HZI73_RS08320	COG3275	phosphorelay sensor kinase activity
HZI73_RS08325	COG2207	Transcriptional regulator
HZI73_RS08335	COG4209	transmembrane transport
HZI73_RS08340	COG0395	ABC-type sugar transport system, permease component
HZI73_RS08370	COG1609	Transcriptional regulator
HZI73_RS08385	COG4209	transmembrane transport
HZI73_RS08390	COG0395	ABC-type sugar transport system, permease component
HZI73_RS08395	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HZI73_RS08400	COG3876	Protein conserved in bacteria
HZI73_RS08405	COG2971	BadF BadG BcrA BcrD
HZI73_RS08420	COG3290	protein histidine kinase activity
HZI73_RS08420	COG0840	transmembrane signaling receptor activity
HZI73_RS08430	COG0071	Belongs to the small heat shock protein (HSP20) family
HZI73_RS08465	COG0716	FMN binding
HZI73_RS08475	COG3275	phosphorelay sensor kinase activity
HZI73_RS08480	COG4753	response regulator
HZI73_RS08480	COG2207	Transcriptional regulator
HZI73_RS08485	COG4213	ABC transporter substrate-binding protein
HZI73_RS08500	COG1172	Belongs to the binding-protein-dependent transport system permease family
HZI73_RS08505	COG4659	FMN binding
HZI73_RS08545	COG0523	cobalamin synthesis protein
HZI73_RS08550	COG2378	regulation of single-species biofilm formation
HZI73_RS08570	COG0714	Associated with various cellular activities
HZI73_RS08605	COG1131	(ABC) transporter
HZI73_RS08615	COG0789	Transcriptional regulator
HZI73_RS08620	COG3459	Glycosyltransferase 36 associated
HZI73_RS08625	COG4753	response regulator
HZI73_RS08625	COG2207	Transcriptional regulator
HZI73_RS08630	COG2972	Histidine kinase
HZI73_RS08645	COG4209	transmembrane transport
HZI73_RS08650	COG0395	ABC-type sugar transport system, permease component
HZI73_RS08655	COG0508	dehydrogenase complex catalyzes the overall conversion of
HZI73_RS08660	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HZI73_RS08715	COG4912	Dna alkylation repair
HZI73_RS08725	COG0346	lactoylglutathione lyase activity
HZI73_RS08755	COG2602	Beta-lactamase
HZI73_RS08765	COG1309	transcriptional regulator
HZI73_RS08775	COG0457	Tetratricopeptide repeat
HZI73_RS08775	COG0463	Glycosyl transferase, family 2
HZI73_RS08780	COG0463	Glycosyl transferase, family 2
HZI73_RS08790	COG0463	Glycosyl transferase, family 2
HZI73_RS08790	COG0457	Tetratricopeptide repeat
HZI73_RS08810	COG3711	transcriptional antiterminator
HZI73_RS08815	COG1263	PTS System
HZI73_RS08815	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HZI73_RS08815	COG2190	(PTS) system
HZI73_RS08820	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HZI73_RS08820	COG2190	(PTS) system
HZI73_RS08820	COG1263	PTS System
HZI73_RS08840	COG1940	carbohydrate kinase activity
HZI73_RS08845	COG1070	Carbohydrate kinase
HZI73_RS08855	COG3773	Cell wall hydrolase
HZI73_RS08875	COG1704	LemA family
HZI73_RS08895	COG3708	Transcriptional regulator
HZI73_RS08895	COG2207	Transcriptional regulator
HZI73_RS08905	COG5002	protein histidine kinase activity
HZI73_RS08910	COG2720	vancomycin resistance protein
HZI73_RS08915	COG2814	Major facilitator Superfamily
HZI73_RS08920	COG2226	methyltransferase
HZI73_RS08925	COG2267	carboxylic ester hydrolase activity
HZI73_RS08940	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
HZI73_RS08950	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HZI73_RS08960	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
HZI73_RS08970	COG0534	Mate efflux family protein
HZI73_RS08990	COG0735	belongs to the Fur family
HZI73_RS08995	COG1132	(ABC) transporter
HZI73_RS09000	COG1132	(ABC) transporter
HZI73_RS09010	COG0803	Belongs to the bacterial solute-binding protein 9 family
HZI73_RS09015	COG1121	(ABC) transporter
HZI73_RS09025	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HZI73_RS09040	COG2972	Histidine kinase
HZI73_RS09045	COG4753	response regulator
HZI73_RS09045	COG2207	Transcriptional regulator
HZI73_RS09045	COG4753	response regulator
HZI73_RS09045	COG2207	Transcriptional regulator
HZI73_RS09055	COG1129	ABC transporter
HZI73_RS09060	COG1172	Belongs to the binding-protein-dependent transport system permease family
HZI73_RS09065	COG1172	Belongs to the binding-protein-dependent transport system permease family
HZI73_RS09090	COG2832	Protein of unknown function (DUF454)
HZI73_RS09115	COG1940	carbohydrate kinase activity
HZI73_RS09140	COG1733	regulation of RNA biosynthetic process
HZI73_RS09150	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
HZI73_RS09160	COG0517	IMP dehydrogenase activity
HZI73_RS09170	COG1129	ABC transporter
HZI73_RS09175	COG1172	Belongs to the binding-protein-dependent transport system permease family
HZI73_RS09190	COG2197	response regulator
HZI73_RS09195	COG2972	Histidine kinase
HZI73_RS09215	COG1609	Transcriptional regulator
HZI73_RS09225	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HZI73_RS09235	COG2972	Histidine kinase
HZI73_RS09240	COG2207	Transcriptional regulator
HZI73_RS09240	COG4753	response regulator
HZI73_RS09250	COG1175	transmembrane transport
HZI73_RS09275	COG0673	inositol 2-dehydrogenase activity
HZI73_RS09285	COG0785	Cytochrome C biogenesis protein
HZI73_RS09290	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HZI73_RS09295	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HZI73_RS09295	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HZI73_RS09300	COG2207	Transcriptional regulator
HZI73_RS09300	COG4753	response regulator
HZI73_RS09305	COG2972	Histidine kinase
HZI73_RS09330	COG1609	Transcriptional regulator
HZI73_RS09335	COG1175	transmembrane transport
HZI73_RS09340	COG0395	ABC-type sugar transport system, permease component
HZI73_RS09345	COG0463	Glycosyl transferase, family 2
HZI73_RS09370	COG3119	arylsulfatase activity
HZI73_RS09380	COG4585	Histidine kinase
HZI73_RS09385	COG2197	response regulator
HZI73_RS09390	COG1131	(ABC) transporter
HZI73_RS09400	COG0842	Transport permease protein
HZI73_RS09410	COG1695	Transcriptional regulator
HZI73_RS09415	COG4619	ABC transporter
HZI73_RS09420	COG0390	transport system, permease component
HZI73_RS09425	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HZI73_RS09445	COG2135	peptidase activity
HZI73_RS09450	COG0584	glycerophosphoryl diester phosphodiesterase
HZI73_RS09455	COG1796	DNA polymerase
HZI73_RS09455	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
HZI73_RS09480	COG0432	Pfam Uncharacterised protein family UPF0047
HZI73_RS09490	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HZI73_RS09495	COG1032	radical SAM domain protein
HZI73_RS09500	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HZI73_RS09515	COG1053	succinate dehydrogenase
HZI73_RS09515	COG0431	NADPH-dependent FMN reductase
HZI73_RS09515	COG3976	FMN-binding domain protein
HZI73_RS09550	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HZI73_RS09555	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HZI73_RS09630	COG0673	inositol 2-dehydrogenase activity
HZI73_RS09635	COG1131	(ABC) transporter
HZI73_RS09660	COG0574	Belongs to the PEP-utilizing enzyme family
HZI73_RS09660	COG3848	Pyruvate phosphate dikinase
HZI73_RS09670	COG0312	modulator of DNA gyrase
HZI73_RS09675	COG0312	modulator of DNA gyrase
HZI73_RS09695	COG1757	Na H antiporter
HZI73_RS09720	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HZI73_RS09735	COG1609	Transcriptional regulator
HZI73_RS09745	COG1609	Transcriptional regulator
HZI73_RS09750	COG1882	Formate acetyltransferase
HZI73_RS09755	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HZI73_RS09760	COG1070	Carbohydrate kinase
HZI73_RS09765	COG1129	ABC transporter
HZI73_RS09770	COG1172	Belongs to the binding-protein-dependent transport system permease family
HZI73_RS09775	COG1879	ABC-type sugar transport system periplasmic component
HZI73_RS09795	COG0191	fructose-bisphosphate aldolase activity
HZI73_RS09800	COG1164	Oligoendopeptidase f
HZI73_RS09815	COG0641	radical SAM
HZI73_RS09840	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HZI73_RS09875	COG1917	Cupin 2, conserved barrel domain protein
HZI73_RS09875	COG2207	Transcriptional regulator
HZI73_RS09890	COG0673	inositol 2-dehydrogenase activity
HZI73_RS09910	COG1725	Transcriptional regulator
HZI73_RS09915	COG0789	Transcriptional regulator
HZI73_RS09935	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HZI73_RS09945	COG4865	methylaspartate mutase activity
HZI73_RS09950	COG3799	methylaspartate ammonia-lyase activity
HZI73_RS09965	COG1349	DNA-binding transcription factor activity
HZI73_RS09970	COG1175	transmembrane transport
HZI73_RS10020	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
HZI73_RS10035	COG2249	NAD(P)H dehydrogenase (quinone) activity
HZI73_RS10095	COG1802	Transcriptional regulator
HZI73_RS10100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HZI73_RS10105	COG2972	Histidine kinase
HZI73_RS10110	COG4753	response regulator
HZI73_RS10110	COG2207	Transcriptional regulator
HZI73_RS10115	COG4209	transmembrane transport
HZI73_RS10120	COG0395	ABC-type sugar transport system, permease component
HZI73_RS10135	COG0488	(ABC) transporter
HZI73_RS10140	COG2996	Protein conserved in bacteria
HZI73_RS10175	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
HZI73_RS10180	COG1840	ABC-type Fe3 transport system, periplasmic component
HZI73_RS10190	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HZI73_RS10215	COG1725	Transcriptional regulator
HZI73_RS10220	COG1131	(ABC) transporter
HZI73_RS10230	COG0813	purine-nucleoside phosphorylase activity
HZI73_RS10240	COG0489	protein tyrosine kinase activity
HZI73_RS10245	COG2894	cell division
HZI73_RS10255	COG0735	belongs to the Fur family
HZI73_RS10275	COG0840	transmembrane signaling receptor activity
HZI73_RS10295	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HZI73_RS10305	COG1592	Rubrerythrin
HZI73_RS10310	COG1414	Transcriptional regulator
HZI73_RS10315	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HZI73_RS10320	COG1028	Short-chain dehydrogenase reductase Sdr
HZI73_RS10330	COG1012	belongs to the aldehyde dehydrogenase family
HZI73_RS10355	COG0513	Belongs to the DEAD box helicase family
HZI73_RS10365	COG0398	Pfam SNARE associated Golgi protein
HZI73_RS10410	COG2323	membrane
HZI73_RS10415	COG0651	ATP synthesis coupled electron transport
HZI73_RS10420	COG1006	Multisubunit Na H antiporter MnhC subunit
HZI73_RS10425	COG2111	Na H antiporter
HZI73_RS10440	COG1320	monovalent cation:proton antiporter activity
HZI73_RS10445	COG2212	antiporter activity
HZI73_RS10475	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
HZI73_RS10480	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
HZI73_RS10490	COG1342	Belongs to the UPF0251 family
HZI73_RS10495	COG2200	EAL domain
HZI73_RS10515	COG1045	serine acetyltransferase
HZI73_RS10520	COG0215	cysteine-tRNA ligase activity
HZI73_RS10530	COG2244	polysaccharide biosynthetic process
HZI73_RS10535	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HZI73_RS10550	COG3688	RNA-binding protein containing a PIN domain
HZI73_RS10580	COG1619	proteins homologs of microcin C7 resistance protein MccF
HZI73_RS10600	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HZI73_RS10605	COG0459	protein refolding
HZI73_RS10615	COG0516	GMP reductase activity
HZI73_RS10615	COG0517	IMP dehydrogenase activity
HZI73_RS10620	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HZI73_RS10625	COG0573	inorganic phosphate transmembrane transporter activity
HZI73_RS10635	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HZI73_RS10640	COG0704	Plays a role in the regulation of phosphate uptake
HZI73_RS10645	COG0745	RESPONSE REGULATOR receiver
HZI73_RS10650	COG5002	protein histidine kinase activity
HZI73_RS10655	COG1554	hydrolase, family 65, central catalytic
HZI73_RS10660	COG1609	Transcriptional regulator
HZI73_RS10680	COG0519	Catalyzes the synthesis of GMP from XMP
HZI73_RS10790	COG2207	Transcriptional regulator
HZI73_RS10790	COG1917	Cupin 2, conserved barrel domain protein
HZI73_RS10800	COG0450	alkyl hydroperoxide reductase
HZI73_RS10805	COG3634	alkyl hydroperoxide reductase activity
HZI73_RS10810	COG3119	arylsulfatase activity
HZI73_RS10825	COG2972	Histidine kinase
HZI73_RS10830	COG2207	Transcriptional regulator
HZI73_RS10830	COG4753	response regulator
HZI73_RS10855	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
HZI73_RS10860	COG4209	transmembrane transport
HZI73_RS10865	COG0395	ABC-type sugar transport system, permease component
HZI73_RS10895	COG2207	Transcriptional regulator
HZI73_RS10895	COG3708	Transcriptional regulator
HZI73_RS10915	COG4209	transmembrane transport
HZI73_RS10920	COG0395	ABC-type sugar transport system, permease component
HZI73_RS10930	COG2252	PERMEase
HZI73_RS10950	COG1882	Formate acetyltransferase
HZI73_RS10955	COG0138	bifunctional purine biosynthesis protein purh
HZI73_RS10960	COG0534	Mate efflux family protein
HZI73_RS10985	COG4555	ABC transporter
HZI73_RS10990	COG1956	GAF domain-containing protein
HZI73_RS10995	COG2972	Histidine kinase
HZI73_RS11000	COG2207	Transcriptional regulator
HZI73_RS11000	COG4753	response regulator
HZI73_RS11005	COG1653	transport
HZI73_RS11010	COG1175	transmembrane transport
HZI73_RS11015	COG0395	ABC-type sugar transport system, permease component
HZI73_RS11025	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HZI73_RS11030	COG1609	Transcriptional regulator
HZI73_RS11035	COG1904	glucuronate isomerase
HZI73_RS11040	COG0800	Aldolase
HZI73_RS11065	COG1132	(ABC) transporter
HZI73_RS11095	COG1122	ATPase activity
HZI73_RS11100	COG1122	ATPase activity
HZI73_RS11125	COG0840	transmembrane signaling receptor activity
HZI73_RS11130	COG0840	transmembrane signaling receptor activity
HZI73_RS11145	COG5002	protein histidine kinase activity
HZI73_RS11145	COG0642	Histidine kinase
HZI73_RS11160	COG1175	transmembrane transport
HZI73_RS11165	COG0395	ABC-type sugar transport system, permease component
HZI73_RS11170	COG1136	(ABC) transporter
HZI73_RS11180	COG1136	(ABC) transporter
HZI73_RS11180	COG0577	efflux transmembrane transporter activity
HZI73_RS11185	COG1381	Involved in DNA repair and RecF pathway recombination
HZI73_RS11190	COG0423	glycine-tRNA ligase activity
HZI73_RS11195	COG0574	Belongs to the PEP-utilizing enzyme family
HZI73_RS11195	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HZI73_RS11200	COG4399	Belongs to the UPF0754 family
HZI73_RS11215	COG0232	Belongs to the dGTPase family. Type 2 subfamily
HZI73_RS11220	COG0358	DNA primase activity
HZI73_RS11225	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HZI73_RS11230	COG2384	SAM-dependent methyltransferase
HZI73_RS11235	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HZI73_RS11240	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HZI73_RS11250	COG5002	protein histidine kinase activity
HZI73_RS11255	COG0745	RESPONSE REGULATOR receiver
HZI73_RS11305	COG0673	inositol 2-dehydrogenase activity
HZI73_RS11310	COG0366	Alpha amylase catalytic
HZI73_RS11330	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HZI73_RS11335	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HZI73_RS11340	COG0826	peptidase U32
HZI73_RS11350	COG3773	Cell wall hydrolase
HZI73_RS11350	COG3409	Peptidoglycan-binding domain 1 protein
HZI73_RS11370	COG0542	response to heat
HZI73_RS11375	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HZI73_RS11385	COG0205	6-phosphofructokinase activity
HZI73_RS11405	COG0287	Prephenate dehydrogenase
HZI73_RS11410	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
HZI73_RS11430	COG0495	leucyl-tRNA aminoacylation
HZI73_RS11455	COG1404	Belongs to the peptidase S8 family
HZI73_RS11470	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HZI73_RS11475	COG0473	3-isopropylmalate dehydrogenase activity
HZI73_RS11480	COG1802	Transcriptional regulator
HZI73_RS11485	COG0321	lipoyl(octanoyl) transferase activity
HZI73_RS11490	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HZI73_RS11495	COG2222	sugar isomerase
HZI73_RS11505	COG2188	Transcriptional regulator
HZI73_RS11510	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HZI73_RS11515	COG1653	transport
HZI73_RS11520	COG1175	transmembrane transport
HZI73_RS11525	COG0395	ABC-type sugar transport system, permease component
HZI73_RS11530	COG2222	sugar isomerase
HZI73_RS11535	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HZI73_RS11540	COG0534	Mate efflux family protein
HZI73_RS11545	COG0488	(ABC) transporter
HZI73_RS11555	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HZI73_RS11560	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HZI73_RS11565	COG0583	DNA-binding transcription factor activity
HZI73_RS11590	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HZI73_RS11590	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HZI73_RS11600	COG2337	Toxic component of a toxin-antitoxin (TA) module
HZI73_RS11610	COG0534	Mate efflux family protein
HZI73_RS11625	COG1136	(ABC) transporter
HZI73_RS11655	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HZI73_RS11660	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HZI73_RS11665	COG0154	amidase activity
HZI73_RS11670	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HZI73_RS11680	COG2746	aminoglycoside 3-N-acetyltransferase activity
HZI73_RS11695	COG1293	RNA-binding protein homologous to eukaryotic snRNP
HZI73_RS11700	COG0372	Belongs to the citrate synthase family
HZI73_RS11710	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HZI73_RS11720	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HZI73_RS11720	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HZI73_RS11735	COG1561	YicC-like family, N-terminal region
HZI73_RS11745	COG0194	GDP metabolic process
HZI73_RS11750	COG1758	RNA polymerase activity
HZI73_RS11755	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HZI73_RS11760	COG0242	peptide deformylase activity
HZI73_RS11765	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HZI73_RS11770	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HZI73_RS11770	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HZI73_RS11775	COG0820	rRNA (adenine-C2-)-methyltransferase activity
HZI73_RS11785	COG0515	serine threonine protein kinase
HZI73_RS11785	COG2815	serine threonine protein kinase
HZI73_RS11790	COG1162	GTPase activity
HZI73_RS11795	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HZI73_RS11810	COG0227	Belongs to the bacterial ribosomal protein bL28 family
HZI73_RS11815	COG1302	Protein conserved in bacteria
HZI73_RS11820	COG1461	Dihydroxyacetone kinase
HZI73_RS11825	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HZI73_RS11835	COG0742	ribosomal rna small subunit methyltransferase
HZI73_RS11840	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HZI73_RS11850	COG3314	Sporulation integral membrane protein YlbJ
HZI73_RS11855	COG1323	Belongs to the UPF0348 family
HZI73_RS11860	COG0280	phosphate acetyltransferase
HZI73_RS11865	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HZI73_RS11870	COG1131	(ABC) transporter
HZI73_RS11885	COG4585	Histidine kinase
HZI73_RS11890	COG2197	response regulator
HZI73_RS11900	COG0333	Belongs to the bacterial ribosomal protein bL32 family
HZI73_RS11905	COG0416	fatty acid biosynthetic process
HZI73_RS11910	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HZI73_RS11925	COG0552	protein localization to endoplasmic reticulum
HZI73_RS11930	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
HZI73_RS11935	COG0347	Belongs to the P(II) protein family
HZI73_RS11940	COG0004	ammonium transporteR
HZI73_RS11950	COG1132	(ABC) transporter
HZI73_RS11955	COG1132	(ABC) transporter
HZI73_RS11970	COG1653	transport
HZI73_RS11980	COG0395	ABC-type sugar transport system, permease component
HZI73_RS11985	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HZI73_RS12000	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HZI73_RS12005	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HZI73_RS12010	COG0228	four-way junction DNA binding
HZI73_RS12020	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HZI73_RS12025	COG0336	Belongs to the RNA methyltransferase TrmD family
HZI73_RS12030	COG0335	large ribosomal subunit rRNA binding
HZI73_RS12040	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HZI73_RS12050	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HZI73_RS12060	COG2257	FlhB HrpN YscU SpaS Family
HZI73_RS12065	COG0792	nuclease activity
HZI73_RS12075	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HZI73_RS12105	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
HZI73_RS12110	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HZI73_RS12115	COG0779	Required for maturation of 30S ribosomal subunits
HZI73_RS12120	COG0195	Participates in both transcription termination and antitermination
HZI73_RS12125	COG2740	Nucleic-acid-binding protein implicated in transcription termination
HZI73_RS12130	COG1358	cellular component organization or biogenesis
HZI73_RS12135	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HZI73_RS12140	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HZI73_RS12145	COG2404	hydrolase activity, acting on ester bonds
HZI73_RS12150	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HZI73_RS12155	COG0196	riboflavin kinase activity
HZI73_RS12160	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HZI73_RS12165	COG1185	polyribonucleotide nucleotidyltransferase activity
HZI73_RS12170	COG0612	Peptidase, M16
HZI73_RS12180	COG0667	Aldo Keto reductase
HZI73_RS12195	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HZI73_RS12275	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HZI73_RS12305	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HZI73_RS12325	COG2304	oxidoreductase activity
HZI73_RS12330	COG1472	Belongs to the glycosyl hydrolase 3 family
HZI73_RS12335	COG1737	Transcriptional regulator
HZI73_RS12340	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
HZI73_RS12345	COG1472	Belongs to the glycosyl hydrolase 3 family
HZI73_RS12350	COG1619	proteins homologs of microcin C7 resistance protein MccF
HZI73_RS12355	COG4948	Mandelate Racemase Muconate Lactonizing
HZI73_RS12370	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HZI73_RS12375	COG0527	aspartate kinase activity
HZI73_RS12380	COG0740	serine-type endopeptidase activity
HZI73_RS12390	COG0789	Transcriptional regulator
HZI73_RS12395	COG1028	Short-chain dehydrogenase reductase Sdr
HZI73_RS12400	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HZI73_RS12415	COG1968	undecaprenyl-diphosphatase activity
HZI73_RS12420	COG1674	ftsk spoiiie
HZI73_RS12425	COG2759	Belongs to the formate--tetrahydrofolate ligase family
HZI73_RS12430	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HZI73_RS12435	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HZI73_RS12440	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HZI73_RS12445	COG1058	Belongs to the CinA family
HZI73_RS12445	COG1546	Belongs to the CinA family
HZI73_RS12460	COG2137	regulation of response to DNA damage stimulus
HZI73_RS12465	COG1418	mRNA catabolic process
HZI73_RS12470	COG2359	stage V sporulation protein S
HZI73_RS12480	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HZI73_RS12485	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HZI73_RS12500	COG4974	Belongs to the 'phage' integrase family
HZI73_RS12515	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HZI73_RS12525	COG3858	chitin binding
HZI73_RS12535	COG2207	Transcriptional regulator
HZI73_RS12550	COG2323	membrane
HZI73_RS12560	COG0456	acetyltransferase
HZI73_RS12570	COG0697	spore germination
HZI73_RS12615	COG1592	Rubrerythrin
HZI73_RS12615	COG1773	rubredoxin
HZI73_RS12620	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
HZI73_RS12630	COG1686	Belongs to the peptidase S11 family
HZI73_RS12635	COG0667	Aldo Keto reductase
HZI73_RS12645	COG3426	butyrate kinase activity
HZI73_RS12650	COG0280	phosphate acetyltransferase
HZI73_RS12655	COG1132	(ABC) transporter
HZI73_RS12665	COG0641	radical SAM
HZI73_RS12680	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HZI73_RS12685	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HZI73_RS12690	COG1686	Belongs to the peptidase S11 family
HZI73_RS12695	COG1187	pseudouridine synthase activity
HZI73_RS12705	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HZI73_RS12715	COG4770	biotin carboxylase activity
HZI73_RS12720	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
HZI73_RS12730	COG1737	Transcriptional regulator
HZI73_RS12735	COG2081	HI0933 family
HZI73_RS12740	COG4401	Chorismate mutase type I
HZI73_RS12745	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
HZI73_RS12750	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HZI73_RS12755	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HZI73_RS12755	COG0539	negative regulation of cytoplasmic translation
HZI73_RS12760	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
HZI73_RS12775	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HZI73_RS12780	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HZI73_RS12790	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HZI73_RS12795	COG1923	regulation of RNA biosynthetic process
HZI73_RS12800	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
HZI73_RS12805	COG0714	Associated with various cellular activities
HZI73_RS12835	COG1131	(ABC) transporter
HZI73_RS12860	COG0456	acetyltransferase
HZI73_RS12870	COG1609	Transcriptional regulator
HZI73_RS12875	COG1176	ABC-type spermidine putrescine transport system, permease component I
HZI73_RS12885	COG3842	ATPase activity
HZI73_RS12890	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HZI73_RS12895	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HZI73_RS12900	COG0402	S-adenosylhomocysteine deaminase activity
HZI73_RS12905	COG0404	The glycine cleavage system catalyzes the degradation of glycine
HZI73_RS12910	COG0509	glycine decarboxylation via glycine cleavage system
HZI73_RS12915	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HZI73_RS12920	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HZI73_RS12925	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HZI73_RS12930	COG1522	sequence-specific DNA binding
HZI73_RS12935	COG0686	Belongs to the AlaDH PNT family
HZI73_RS12970	COG0793	Belongs to the peptidase S41A family
HZI73_RS12990	COG1193	negative regulation of DNA recombination
HZI73_RS12995	COG2315	Protein conserved in bacteria
HZI73_RS13010	COG0668	transmembrane transport
HZI73_RS13015	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HZI73_RS13020	COG0551	DNA topoisomerase type I activity
HZI73_RS13020	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HZI73_RS13040	COG0539	negative regulation of cytoplasmic translation
HZI73_RS13040	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HZI73_RS13045	COG1609	Transcriptional regulator
HZI73_RS13050	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HZI73_RS13115	COG0393	Putative heavy-metal-binding
HZI73_RS13135	COG5002	protein histidine kinase activity
HZI73_RS13145	COG2015	COG2015, Alkyl sulfatase and related hydrolases
HZI73_RS13165	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HZI73_RS13175	COG0402	S-adenosylhomocysteine deaminase activity
HZI73_RS13185	COG4753	response regulator
HZI73_RS13185	COG2207	Transcriptional regulator
HZI73_RS13190	COG2972	Histidine kinase
HZI73_RS13260	COG0012	GTP binding
HZI73_RS13280	COG2001	Belongs to the MraZ family
HZI73_RS13285	COG0275	rRNA processing
HZI73_RS13295	COG0768	penicillin binding
HZI73_RS13300	COG0768	penicillin binding
HZI73_RS13305	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HZI73_RS13310	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HZI73_RS13315	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HZI73_RS13325	COG0772	Belongs to the SEDS family
HZI73_RS13330	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HZI73_RS13340	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HZI73_RS13350	COG1191	sigma factor activity
HZI73_RS13355	COG1191	sigma factor activity
HZI73_RS13365	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HZI73_RS13370	COG0606	chelatase, subunit chli
HZI73_RS13380	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HZI73_RS13385	COG2348	transferase activity, transferring amino-acyl groups
HZI73_RS13390	COG0758	DNA mediated transformation
HZI73_RS13395	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HZI73_RS13405	COG1815	bacterial-type flagellum-dependent cell motility
HZI73_RS13415	COG1677	Flagellar hook-basal body complex protein FliE
HZI73_RS13420	COG1766	The M ring may be actively involved in energy transduction
HZI73_RS13425	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HZI73_RS13450	COG3144	bacterial-type flagellum assembly
HZI73_RS13455	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
HZI73_RS13480	COG1360	Flagellar Motor Protein
HZI73_RS13490	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HZI73_RS13495	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HZI73_RS13495	COG1776	CheC inhibitor of MCP methylation
HZI73_RS13500	COG2201	protein-glutamate methylesterase activity
HZI73_RS13510	COG1338	Plays a role in the flagellum-specific transport system
HZI73_RS13515	COG1987	bacterial-type flagellum assembly
HZI73_RS13520	COG1684	flagellar biosynthetic protein fliR
HZI73_RS13525	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HZI73_RS13530	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HZI73_RS13535	COG1419	protein localization to endoplasmic reticulum
HZI73_RS13550	COG2201	protein-glutamate methylesterase activity
HZI73_RS13555	COG0643	Histidine kinase
HZI73_RS13555	COG2198	Histidine kinase
HZI73_RS13565	COG1776	CheC inhibitor of MCP methylation
HZI73_RS13570	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
HZI73_RS13580	COG1191	sigma factor activity
HZI73_RS13605	COG0052	Belongs to the universal ribosomal protein uS2 family
HZI73_RS13610	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HZI73_RS13615	COG0528	UMP kinase activity
HZI73_RS13620	COG0233	cytoplasmic translational termination
HZI73_RS13630	COG0575	Belongs to the CDS family
HZI73_RS13640	COG0750	zinc metalloprotease
HZI73_RS13645	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HZI73_RS13655	COG0733	neurotransmitter:sodium symporter activity
HZI73_RS13665	COG0328	RNA-DNA hybrid ribonuclease activity
HZI73_RS13670	COG0142	geranyltranstransferase activity
HZI73_RS13680	COG2357	RelA SpoT domain protein
HZI73_RS13690	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HZI73_RS13690	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
HZI73_RS13695	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HZI73_RS13715	COG1686	Belongs to the peptidase S11 family
HZI73_RS13725	COG4221	oxidoreductase activity
HZI73_RS13730	COG1525	nuclease
HZI73_RS13740	COG1028	Short-chain dehydrogenase reductase Sdr
HZI73_RS13745	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HZI73_RS13750	COG2207	Transcriptional regulator
HZI73_RS13750	COG0662	Cupin 2, conserved barrel domain protein
HZI73_RS13775	COG0351	phosphomethylpyrimidine kinase
HZI73_RS13775	COG0352	thiamine-phosphate diphosphorylase activity
HZI73_RS13780	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HZI73_RS13785	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HZI73_RS13805	COG0564	pseudouridine synthase activity
HZI73_RS13810	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HZI73_RS13815	COG3331	DNA recombination
HZI73_RS13845	COG0124	histidyl-tRNA synthetase
HZI73_RS13850	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
HZI73_RS13855	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HZI73_RS13860	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HZI73_RS13865	COG0131	Imidazoleglycerol-phosphate dehydratase
HZI73_RS13870	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HZI73_RS13875	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HZI73_RS13910	COG1027	Aspartate ammonia-lyase
HZI73_RS13920	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HZI73_RS13925	COG0745	RESPONSE REGULATOR receiver
HZI73_RS13930	COG2205	protein histidine kinase activity
HZI73_RS13935	COG1131	(ABC) transporter
HZI73_RS13975	COG4656	Part of a membrane complex involved in electron transport
HZI73_RS13980	COG4658	electron transport chain
HZI73_RS13990	COG4660	Part of a membrane complex involved in electron transport
HZI73_RS13995	COG4657	Part of a membrane complex involved in electron transport
HZI73_RS14000	COG1245	4Fe-4S binding domain
HZI73_RS14000	COG2878	Part of a membrane complex involved in electron transport
HZI73_RS14010	COG0424	maF-like protein
HZI73_RS14015	COG2003	Belongs to the UPF0758 family
HZI73_RS14020	COG1077	Cell shape determining protein MreB Mrl
HZI73_RS14035	COG0768	penicillin binding
HZI73_RS14045	COG2894	cell division
HZI73_RS14050	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
HZI73_RS14055	COG0772	Belongs to the SEDS family
HZI73_RS14060	COG1803	Methylglyoxal synthase
HZI73_RS14070	COG2155	Conserved Protein
HZI73_RS14110	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
HZI73_RS14140	COG1966	Carbon starvation protein
HZI73_RS14150	COG3275	phosphorelay sensor kinase activity
HZI73_RS14165	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HZI73_RS14175	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HZI73_RS14180	COG1799	cell septum assembly
HZI73_RS14185	COG0762	integral membrane protein
HZI73_RS14190	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HZI73_RS14195	COG3599	regulation of cell shape
HZI73_RS14200	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HZI73_RS14210	COG0564	pseudouridine synthase activity
HZI73_RS14215	COG0246	Mannitol dehydrogenase
HZI73_RS14220	COG2721	sulfolactate sulfo-lyase activity
HZI73_RS14225	COG0673	inositol 2-dehydrogenase activity
HZI73_RS14230	COG2207	Transcriptional regulator
HZI73_RS14235	COG4106	trans-aconitate 2-methyltransferase activity
HZI73_RS14245	COG4974	Belongs to the 'phage' integrase family
HZI73_RS14275	COG0534	Mate efflux family protein
HZI73_RS14290	COG1051	belongs to the nudix hydrolase family
HZI73_RS14305	COG0187	DNA topoisomerase II activity
HZI73_RS14310	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HZI73_RS14315	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HZI73_RS14320	COG1309	transcriptional regulator
HZI73_RS14325	COG1012	belongs to the aldehyde dehydrogenase family
HZI73_RS14335	COG2226	methyltransferase
HZI73_RS14350	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HZI73_RS14355	COG2022	thiamine diphosphate biosynthetic process
HZI73_RS14365	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HZI73_RS14370	COG2233	PERMEase
HZI73_RS14380	COG3119	arylsulfatase activity
HZI73_RS14385	COG3119	arylsulfatase activity
HZI73_RS14390	COG3858	chitin binding
HZI73_RS14395	COG0540	Belongs to the ATCase OTCase family
HZI73_RS14400	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HZI73_RS14410	COG2217	Heavy metal translocating P-type atpase
HZI73_RS14415	COG2207	Transcriptional regulator
HZI73_RS14445	COG0640	Transcriptional regulator
HZI73_RS14460	COG1361	Conserved repeat domain
HZI73_RS14460	COG2911	Protein conserved in bacteria
HZI73_RS14460	COG3266	domain, Protein
HZI73_RS14465	COG1695	Transcriptional regulator
HZI73_RS14470	COG0596	Alpha beta hydrolase
HZI73_RS14495	COG0693	protein deglycase activity
HZI73_RS14500	COG2378	regulation of single-species biofilm formation
HZI73_RS14515	COG3858	chitin binding
HZI73_RS14515	COG1388	LysM domain
HZI73_RS14520	COG0037	tRNA processing
HZI73_RS14525	COG4974	Belongs to the 'phage' integrase family
HZI73_RS14535	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HZI73_RS14540	COG0799	negative regulation of ribosome biogenesis
HZI73_RS14545	COG1713	HD superfamily hydrolase involved in NAD metabolism
HZI73_RS14565	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HZI73_RS14570	COG0211	Belongs to the bacterial ribosomal protein bL27 family
HZI73_RS14580	COG0261	This protein binds to 23S rRNA in the presence of protein L20
HZI73_RS14585	COG1530	ribonuclease E activity
HZI73_RS14605	COG0367	asparagine synthase
HZI73_RS14610	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HZI73_RS14620	COG1773	rubredoxin
HZI73_RS14630	COG0730	response to heat
HZI73_RS14635	COG0246	Mannitol dehydrogenase
HZI73_RS14640	COG1312	Catalyzes the dehydration of D-mannonate
HZI73_RS14650	COG2195	Cleaves the N-terminal amino acid of tripeptides
HZI73_RS14655	COG2848	UPF0210 protein
HZI73_RS14665	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HZI73_RS14685	COG0237	dephospho-CoA kinase activity
HZI73_RS14690	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HZI73_RS14690	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HZI73_RS14700	COG1595	DNA-templated transcription, initiation
HZI73_RS14725	COG1309	transcriptional regulator
HZI73_RS14790	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
HZI73_RS14790	COG2273	Hydrolase Family 16
HZI73_RS14795	COG0402	S-adenosylhomocysteine deaminase activity
HZI73_RS14805	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HZI73_RS14810	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HZI73_RS14820	COG2080	2 iron, 2 sulfur cluster binding
HZI73_RS14825	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
HZI73_RS14830	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HZI73_RS14835	COG0549	Belongs to the carbamate kinase family
HZI73_RS14840	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HZI73_RS14845	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HZI73_RS14855	COG0402	S-adenosylhomocysteine deaminase activity
HZI73_RS14860	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HZI73_RS14860	COG0493	'glutamate synthase
HZI73_RS14880	COG1129	ABC transporter
HZI73_RS14885	COG2201	protein-glutamate methylesterase activity
HZI73_RS14890	COG2972	Histidine kinase
HZI73_RS14910	COG3608	succinylglutamate desuccinylase aspartoacylase
HZI73_RS14910	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HZI73_RS14915	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
HZI73_RS14920	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HZI73_RS14945	COG1051	belongs to the nudix hydrolase family
HZI73_RS14950	COG0768	penicillin binding
HZI73_RS14960	COG0826	peptidase U32
HZI73_RS14975	COG2255	four-way junction helicase activity
HZI73_RS14980	COG0632	four-way junction helicase activity
HZI73_RS15005	COG0723	plastoquinol--plastocyanin reductase activity
HZI73_RS15015	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HZI73_RS15025	COG0561	phosphatase activity
HZI73_RS15030	COG3711	transcriptional antiterminator
HZI73_RS15035	COG2190	(PTS) system
HZI73_RS15035	COG1263	PTS System
HZI73_RS15035	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HZI73_RS15060	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HZI73_RS15065	COG4224	UPF0291 protein
HZI73_RS15075	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HZI73_RS15080	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HZI73_RS15085	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
HZI73_RS15090	COG2081	HI0933 family
HZI73_RS15095	COG1472	Belongs to the glycosyl hydrolase 3 family
HZI73_RS15105	COG0728	peptidoglycan biosynthetic process
HZI73_RS15110	COG0295	cytidine deaminase activity
HZI73_RS15115	COG1470	cell adhesion involved in biofilm formation
HZI73_RS15120	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HZI73_RS15125	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HZI73_RS15135	COG1702	phosphate starvation-inducible protein PhoH
HZI73_RS15150	COG1610	YqeY-like protein
HZI73_RS15155	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HZI73_RS15165	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HZI73_RS15180	COG0395	ABC-type sugar transport system, permease component
HZI73_RS15195	COG1609	Transcriptional regulator
HZI73_RS15200	COG1388	LysM domain
HZI73_RS15200	COG3942	CHAP domain
HZI73_RS15210	COG0697	spore germination
HZI73_RS15215	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HZI73_RS15225	COG2323	membrane
HZI73_RS15230	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HZI73_RS15235	COG0488	(ABC) transporter
HZI73_RS15250	COG0285	dihydrofolate synthase activity
HZI73_RS15255	COG0521	Mo-molybdopterin cofactor biosynthetic process
HZI73_RS15295	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HZI73_RS15305	COG1136	(ABC) transporter
HZI73_RS15310	COG0577	efflux transmembrane transporter activity
HZI73_RS15320	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HZI73_RS15345	COG1944	ATP diphosphatase activity
HZI73_RS15360	COG0840	transmembrane signaling receptor activity
HZI73_RS15375	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HZI73_RS15380	COG2205	protein histidine kinase activity
HZI73_RS15390	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HZI73_RS15395	COG1486	melibiose metabolic process
HZI73_RS15400	COG0395	ABC-type sugar transport system, permease component
HZI73_RS15410	COG1653	transport
HZI73_RS15430	COG0745	RESPONSE REGULATOR receiver
HZI73_RS15435	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HZI73_RS15440	COG2200	EAL domain
HZI73_RS15440	COG2199	diguanylate cyclase activity
HZI73_RS15440	COG3287	FIST C domain
HZI73_RS15450	COG3285	dna ligase
HZI73_RS15450	COG1793	dna ligase
HZI73_RS15455	COG1793	dna ligase
HZI73_RS15460	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HZI73_RS15480	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HZI73_RS15500	COG1361	Conserved repeat domain
HZI73_RS15500	COG2911	Protein conserved in bacteria
HZI73_RS15500	COG3266	domain, Protein
HZI73_RS15520	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HZI73_RS15525	COG1011	Hydrolase
HZI73_RS15530	COG0706	membrane insertase activity
HZI73_RS15535	COG0384	phenazine biosynthesis protein PhzF
HZI73_RS15555	COG3340	Belongs to the peptidase S51 family
HZI73_RS15580	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
HZI73_RS15680	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HZI73_RS15685	COG0427	acetyl-CoA hydrolase
HZI73_RS15690	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HZI73_RS15735	COG0183	Belongs to the thiolase family
HZI73_RS15740	COG1028	Short-chain dehydrogenase reductase Sdr
HZI73_RS15760	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HZI73_RS15775	COG0824	Thioesterase
HZI73_RS15785	COG1609	Transcriptional regulator
HZI73_RS15795	COG1917	Cupin 2, conserved barrel domain protein
HZI73_RS15795	COG2169	Transcriptional regulator
HZI73_RS15810	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
HZI73_RS15825	COG0395	ABC-type sugar transport system, permease component
HZI73_RS15830	COG4209	transmembrane transport
HZI73_RS15835	COG2972	Histidine kinase
HZI73_RS15840	COG4753	response regulator
HZI73_RS15840	COG2207	Transcriptional regulator
HZI73_RS15855	COG4977	sequence-specific DNA binding
HZI73_RS15855	COG1917	Cupin 2, conserved barrel domain protein
HZI73_RS15870	COG1917	Cupin 2, conserved barrel domain protein
HZI73_RS15870	COG4977	sequence-specific DNA binding
HZI73_RS15875	COG1501	Belongs to the glycosyl hydrolase 31 family
HZI73_RS15880	COG0395	ABC-type sugar transport system, permease component
HZI73_RS15885	COG1175	transmembrane transport
HZI73_RS15905	COG0698	ribose 5-phosphate isomerase
HZI73_RS15910	COG3958	Transketolase
HZI73_RS15915	COG3959	Transketolase, thiamine diphosphate binding domain
HZI73_RS15920	COG0471	metal ion transport
HZI73_RS15925	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HZI73_RS15930	COG0045	succinate-CoA ligase (ADP-forming) activity
HZI73_RS15935	COG1012	belongs to the aldehyde dehydrogenase family
HZI73_RS15950	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HZI73_RS15955	COG0124	histidyl-tRNA synthetase
HZI73_RS15960	COG0159	tryptophan synthase activity
HZI73_RS15965	COG0133	tryptophan synthase activity
HZI73_RS15970	COG0135	phosphoribosylanthranilate isomerase activity
HZI73_RS15975	COG0134	indole-3-glycerol-phosphate synthase activity
HZI73_RS15980	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HZI73_RS15985	COG0512	Glutamine amidotransferase of anthranilate synthase
HZI73_RS15985	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HZI73_RS15995	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HZI73_RS16000	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HZI73_RS16005	COG1490	D-aminoacyl-tRNA deacylase activity
HZI73_RS16010	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HZI73_RS16030	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HZI73_RS16040	COG0725	ABC transporter, periplasmic molybdate-binding protein
HZI73_RS16050	COG0535	radical SAM domain protein
HZI73_RS16055	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
HZI73_RS16075	COG0347	Belongs to the P(II) protein family
HZI73_RS16085	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
HZI73_RS16095	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HZI73_RS16100	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HZI73_RS16100	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
HZI73_RS16105	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HZI73_RS16105	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HZI73_RS16110	COG0820	rRNA (adenine-C2-)-methyltransferase activity
HZI73_RS16125	COG0613	PHP domain protein
HZI73_RS16140	COG1862	Preprotein translocase
HZI73_RS16145	COG0343	queuine tRNA-ribosyltransferase activity
HZI73_RS16150	COG3300	MHYT domain
HZI73_RS16150	COG5001	Diguanylate cyclase
HZI73_RS16160	COG0803	Belongs to the bacterial solute-binding protein 9 family
HZI73_RS16165	COG1121	(ABC) transporter
HZI73_RS16170	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HZI73_RS16175	COG1725	Transcriptional regulator
HZI73_RS16215	COG2244	polysaccharide biosynthetic process
HZI73_RS16235	COG0395	ABC-type sugar transport system, permease component
HZI73_RS16240	COG1175	transmembrane transport
HZI73_RS16250	COG1609	Transcriptional regulator
HZI73_RS16255	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
HZI73_RS16265	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HZI73_RS16295	COG0154	amidase activity
HZI73_RS16340	COG3119	arylsulfatase activity
HZI73_RS16345	COG1082	Xylose isomerase domain protein TIM barrel
HZI73_RS16350	COG1472	Belongs to the glycosyl hydrolase 3 family
HZI73_RS16365	COG3250	beta-galactosidase activity
HZI73_RS16375	COG0395	ABC-type sugar transport system, permease component
HZI73_RS16380	COG4209	transmembrane transport
HZI73_RS16390	COG3275	phosphorelay sensor kinase activity
HZI73_RS16395	COG2207	Transcriptional regulator
HZI73_RS16395	COG4753	response regulator
HZI73_RS16445	COG1082	Xylose isomerase domain protein TIM barrel
HZI73_RS16450	COG0673	inositol 2-dehydrogenase activity
HZI73_RS16455	COG0644	oxidoreductase
HZI73_RS16460	COG0406	alpha-ribazole phosphatase activity
HZI73_RS16465	COG3706	GGDEF domain
HZI73_RS16470	COG1550	Protein conserved in bacteria
HZI73_RS16495	COG1929	Belongs to the glycerate kinase type-1 family
HZI73_RS16505	COG3835	regulator
HZI73_RS16520	COG0750	zinc metalloprotease
HZI73_RS16525	COG0497	DNA recombination
HZI73_RS16530	COG1438	arginine binding
HZI73_RS16535	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HZI73_RS16540	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
HZI73_RS16545	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HZI73_RS16570	COG1570	exodeoxyribonuclease VII activity
HZI73_RS16575	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HZI73_RS16580	COG1302	Protein conserved in bacteria
HZI73_RS16620	COG3854	ATPases associated with a variety of cellular activities
HZI73_RS16630	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HZI73_RS16635	COG0006	proline dipeptidase activity
HZI73_RS16640	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
HZI73_RS16650	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HZI73_RS16655	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
HZI73_RS16665	COG1335	isochorismatase
HZI73_RS16770	COG1131	(ABC) transporter
HZI73_RS16785	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HZI73_RS16795	COG1011	Hydrolase
HZI73_RS16815	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HZI73_RS16820	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HZI73_RS16830	COG0107	imidazoleglycerol-phosphate synthase activity
HZI73_RS16870	COG0826	peptidase U32
HZI73_RS16875	COG4122	O-methyltransferase activity
HZI73_RS16880	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HZI73_RS16890	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HZI73_RS16895	COG0735	belongs to the Fur family
HZI73_RS16905	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HZI73_RS16910	COG4472	Bacterial protein of unknown function (DUF965)
HZI73_RS16915	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HZI73_RS16935	COG0301	tRNA thio-modification
HZI73_RS16945	COG2201	protein-glutamate methylesterase activity
HZI73_RS16950	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HZI73_RS16955	COG2264	protein methyltransferase activity
HZI73_RS16960	COG0484	heat shock protein binding
HZI73_RS16965	COG0443	Heat shock 70 kDa protein
HZI73_RS16970	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HZI73_RS16975	COG1420	regulation of RNA biosynthetic process
HZI73_RS16980	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HZI73_RS16985	COG0481	GTPase activity
HZI73_RS16995	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HZI73_RS17000	COG0268	Binds directly to 16S ribosomal RNA
HZI73_RS17015	COG1073	alpha beta
HZI73_RS17020	COG2333	competence protein COMEC
HZI73_RS17020	COG0658	competence protein
HZI73_RS17030	COG5002	protein histidine kinase activity
HZI73_RS17035	COG0745	RESPONSE REGULATOR receiver
HZI73_RS17040	COG1555	photosystem II stabilization
HZI73_RS17050	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
HZI73_RS17050	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HZI73_RS17060	COG2200	EAL domain
HZI73_RS17065	COG0789	Transcriptional regulator
HZI73_RS17075	COG1305	Transglutaminase-like
HZI73_RS17085	COG0714	Associated with various cellular activities
HZI73_RS17115	COG0442	prolyl-tRNA aminoacylation
HZI73_RS17130	COG0737	Belongs to the 5'-nucleotidase family
HZI73_RS17145	COG0701	Predicted permease
HZI73_RS17150	COG1132	(ABC) transporter
HZI73_RS17155	COG1132	(ABC) transporter
HZI73_RS17155	COG2375	cellular response to nickel ion
HZI73_RS17160	COG2226	methyltransferase
HZI73_RS17170	COG0735	belongs to the Fur family
HZI73_RS17180	COG4716	Myosin-crossreactive antigen
HZI73_RS17185	COG1573	uracil-dna glycosylase
HZI73_RS17190	COG1132	(ABC) transporter
HZI73_RS17195	COG1132	(ABC) transporter
HZI73_RS17205	COG2207	Transcriptional regulator
HZI73_RS17215	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HZI73_RS17215	COG0493	'glutamate synthase
HZI73_RS17225	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HZI73_RS17230	COG0505	Belongs to the CarA family
HZI73_RS17235	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HZI73_RS17240	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HZI73_RS17245	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HZI73_RS17250	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HZI73_RS17255	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HZI73_RS17260	COG0137	argininosuccinate synthase activity
HZI73_RS17265	COG0165	Argininosuccinate lyase
HZI73_RS17285	COG1595	DNA-templated transcription, initiation
HZI73_RS17295	COG1309	transcriptional regulator
HZI73_RS17300	COG0534	Mate efflux family protein
HZI73_RS17310	COG1361	Conserved repeat domain
HZI73_RS17315	COG2190	(PTS) system
HZI73_RS17320	COG2190	(PTS) system
HZI73_RS17320	COG1263	PTS System
HZI73_RS17320	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HZI73_RS17345	COG0312	modulator of DNA gyrase
HZI73_RS17365	COG4536	flavin adenine dinucleotide binding
HZI73_RS17375	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HZI73_RS17385	COG0330	HflC and HflK could
HZI73_RS17400	COG0028	Belongs to the TPP enzyme family
HZI73_RS17405	COG0129	dihydroxy-acid dehydratase activity
HZI73_RS17410	COG0473	3-isopropylmalate dehydrogenase activity
HZI73_RS17415	COG0066	3-isopropylmalate dehydratase activity
HZI73_RS17420	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HZI73_RS17425	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HZI73_RS17430	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HZI73_RS17460	COG0348	domain, Protein
HZI73_RS17460	COG3901	Regulator of nitric oxide reductase transcription
HZI73_RS17470	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HZI73_RS17485	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HZI73_RS17490	COG1518	maintenance of DNA repeat elements
HZI73_RS17525	COG2378	regulation of single-species biofilm formation
HZI73_RS17565	COG1126	abc transporter atp-binding protein
HZI73_RS17570	COG0765	amino acid transport
HZI73_RS17575	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HZI73_RS17590	COG0646	methionine synthase
HZI73_RS17590	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HZI73_RS17620	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HZI73_RS17620	COG0551	DNA topoisomerase type I activity
HZI73_RS17625	COG1307	EDD domain protein, DegV family
HZI73_RS17630	COG0530	calcium, potassium:sodium antiporter activity
HZI73_RS17650	COG0789	Transcriptional regulator
HZI73_RS17670	COG3457	Alanine racemase
HZI73_RS17680	COG5012	cobalamin binding
HZI73_RS17690	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HZI73_RS17700	COG3804	dihydrodipicolinate reductase
HZI73_RS17705	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HZI73_RS17710	COG2235	arginine
HZI73_RS17740	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HZI73_RS17745	COG0673	inositol 2-dehydrogenase activity
HZI73_RS17755	COG3962	Belongs to the TPP enzyme family
HZI73_RS17770	COG1012	belongs to the aldehyde dehydrogenase family
HZI73_RS17775	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HZI73_RS17785	COG0673	inositol 2-dehydrogenase activity
HZI73_RS17790	COG1172	Belongs to the binding-protein-dependent transport system permease family
HZI73_RS17795	COG1129	ABC transporter
HZI73_RS17800	COG1879	ABC-type sugar transport system periplasmic component
HZI73_RS17810	COG2972	Histidine kinase
HZI73_RS17825	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HZI73_RS17835	COG3250	beta-galactosidase activity
HZI73_RS17840	COG0737	Belongs to the 5'-nucleotidase family
HZI73_RS17855	COG3708	Transcriptional regulator
HZI73_RS17855	COG2207	Transcriptional regulator
HZI73_RS17860	COG0778	Nitroreductase
HZI73_RS17865	COG0277	FAD linked oxidase domain protein
HZI73_RS17890	COG1131	(ABC) transporter
HZI73_RS17895	COG0395	ABC-type sugar transport system, permease component
HZI73_RS17900	COG4209	transmembrane transport
HZI73_RS17905	COG1653	transport
HZI73_RS17910	COG1609	Transcriptional regulator
HZI73_RS17910	COG2207	Transcriptional regulator
HZI73_RS17925	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
HZI73_RS17930	COG1473	amidohydrolase
HZI73_RS17945	COG3404	Formiminotransferase-cyclodeaminase
HZI73_RS17960	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HZI73_RS17965	COG2986	histidine ammonia-lyase
HZI73_RS17980	COG3708	Transcriptional regulator
HZI73_RS17980	COG2207	Transcriptional regulator
HZI73_RS17990	COG0596	Alpha beta hydrolase
HZI73_RS17995	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HZI73_RS18000	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HZI73_RS18005	COG1193	negative regulation of DNA recombination
HZI73_RS18015	COG1509	lysine 2,3-aminomutase activity
HZI73_RS18020	COG0604	alcohol dehydrogenase
HZI73_RS18035	COG3246	L-lysine catabolic process to acetate
HZI73_RS18040	COG1607	acyl-coa hydrolase
HZI73_RS18045	COG0386	Belongs to the glutathione peroxidase family
HZI73_RS18050	COG0653	protein targeting
HZI73_RS18055	COG2188	Transcriptional regulator
HZI73_RS18070	COG0446	pyridine nucleotide-disulphide oxidoreductase
HZI73_RS18075	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HZI73_RS18080	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
HZI73_RS18110	COG1595	DNA-templated transcription, initiation
HZI73_RS18125	COG2132	Multicopper oxidase
HZI73_RS18140	COG3848	Pyruvate phosphate dikinase
HZI73_RS18140	COG0574	Belongs to the PEP-utilizing enzyme family
HZI73_RS18155	COG5566	PFAM Mor transcription activator
HZI73_RS18185	COG1733	regulation of RNA biosynthetic process
HZI73_RS18195	COG0793	Belongs to the peptidase S41A family
HZI73_RS18225	COG0662	Cupin 2, conserved barrel domain protein
HZI73_RS18245	COG3620	sequence-specific DNA binding
HZI73_RS18265	COG0596	Alpha beta hydrolase
HZI73_RS18285	COG1733	regulation of RNA biosynthetic process
HZI73_RS18290	COG0655	NAD(P)H dehydrogenase (quinone) activity
HZI73_RS18300	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HZI73_RS18315	COG0557	exoribonuclease II activity
HZI73_RS18335	COG0148	phosphopyruvate hydratase activity
HZI73_RS18340	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HZI73_RS18345	COG0149	triose-phosphate isomerase activity
HZI73_RS18360	COG2390	Transcriptional regulator
HZI73_RS18370	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
HZI73_RS18380	COG0482	sulfurtransferase activity
HZI73_RS18385	COG0822	iron-sulfur transferase activity
HZI73_RS18395	COG1959	2 iron, 2 sulfur cluster binding
HZI73_RS18405	COG0542	response to heat
HZI73_RS18415	COG2385	sporulation resulting in formation of a cellular spore
HZI73_RS18415	COG2247	cell wall binding repeat
HZI73_RS18420	COG1126	abc transporter atp-binding protein
HZI73_RS18425	COG0765	amino acid transport
HZI73_RS18430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HZI73_RS18440	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HZI73_RS18455	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HZI73_RS18460	COG2205	protein histidine kinase activity
HZI73_RS18465	COG0745	RESPONSE REGULATOR receiver
HZI73_RS18470	COG1509	lysine 2,3-aminomutase activity
HZI73_RS18490	COG0488	(ABC) transporter
HZI73_RS18515	COG0577	efflux transmembrane transporter activity
HZI73_RS18520	COG1136	(ABC) transporter
HZI73_RS18525	COG0028	Belongs to the TPP enzyme family
HZI73_RS18530	COG2207	Transcriptional regulator
HZI73_RS18550	COG0395	ABC-type sugar transport system, permease component
HZI73_RS18555	COG4209	transmembrane transport
HZI73_RS18570	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
HZI73_RS18575	COG2207	Transcriptional regulator
HZI73_RS18575	COG1917	Cupin 2, conserved barrel domain protein
HZI73_RS18585	COG1959	2 iron, 2 sulfur cluster binding
HZI73_RS18595	COG1295	ribonuclease BN
HZI73_RS18620	COG0069	glutamate synthase activity
HZI73_RS18620	COG0067	glutamate synthase
HZI73_RS18620	COG0070	glutamate synthase
HZI73_RS18630	COG1181	Belongs to the D-alanine--D-alanine ligase family
HZI73_RS18635	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HZI73_RS18665	COG2610	gluconate transmembrane transporter activity
HZI73_RS18670	COG1929	Belongs to the glycerate kinase type-1 family
HZI73_RS18675	COG3835	regulator
HZI73_RS18680	COG1151	hydroxylamine reductase activity
HZI73_RS18700	COG0596	Alpha beta hydrolase
HZI73_RS18710	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HZI73_RS18725	COG3119	arylsulfatase activity
HZI73_RS18735	COG1472	Belongs to the glycosyl hydrolase 3 family
HZI73_RS18750	COG0395	ABC-type sugar transport system, permease component
HZI73_RS18755	COG4209	transmembrane transport
HZI73_RS18760	COG2972	Histidine kinase
HZI73_RS18765	COG4753	response regulator
HZI73_RS18765	COG2207	Transcriptional regulator
HZI73_RS18780	COG1028	Short-chain dehydrogenase reductase Sdr
HZI73_RS18815	COG3328	transposase activity
HZI73_RS18820	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HZI73_RS18830	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HZI73_RS18840	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HZI73_RS18860	COG3250	beta-galactosidase activity
HZI73_RS18870	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HZI73_RS18875	COG4106	trans-aconitate 2-methyltransferase activity
HZI73_RS18890	COG0572	uridine kinase
HZI73_RS18910	COG0024	Methionine aminopeptidase
HZI73_RS18915	COG0513	Belongs to the DEAD box helicase family
HZI73_RS18930	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HZI73_RS18935	COG0438	transferase activity, transferring glycosyl groups
HZI73_RS18940	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HZI73_RS18945	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HZI73_RS18960	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
HZI73_RS18975	COG1979	alcohol dehydrogenase
HZI73_RS18980	COG0789	Transcriptional regulator
HZI73_RS19015	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
HZI73_RS19020	COG3833	ABC-type maltose transport systems, permease component
HZI73_RS19025	COG1175	transmembrane transport
HZI73_RS19030	COG2182	Extracellular solute-binding protein
HZI73_RS19040	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
HZI73_RS19045	COG2942	2-epimerase
HZI73_RS19065	COG4716	Myosin-crossreactive antigen
HZI73_RS19085	COG1131	(ABC) transporter
HZI73_RS19095	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HZI73_RS19120	COG0714	Associated with various cellular activities
HZI73_RS19125	COG1653	transport
HZI73_RS19135	COG1131	(ABC) transporter
HZI73_RS19165	COG0395	ABC-type sugar transport system, permease component
HZI73_RS19170	COG4209	transmembrane transport
HZI73_RS19180	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HZI73_RS19190	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
HZI73_RS19195	COG2086	electron transfer activity
HZI73_RS19200	COG1960	acyl-CoA dehydrogenase activity
HZI73_RS19205	COG2030	dehydratase
HZI73_RS19240	COG4636	protein conserved in cyanobacteria
HZI73_RS19245	COG4166	transmembrane transport
HZI73_RS19250	COG4608	Belongs to the ABC transporter superfamily
HZI73_RS19255	COG0444	Belongs to the ABC transporter superfamily
HZI73_RS19260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HZI73_RS19265	COG0601	transmembrane transport
HZI73_RS19280	COG1960	acyl-CoA dehydrogenase activity
HZI73_RS19285	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
HZI73_RS19290	COG2086	electron transfer activity
HZI73_RS19315	COG0410	ABC transporter
HZI73_RS19325	COG0604	alcohol dehydrogenase
HZI73_RS19330	COG1846	Transcriptional regulator
HZI73_RS19335	COG0446	pyridine nucleotide-disulphide oxidoreductase
HZI73_RS19340	COG0628	permease
HZI73_RS19360	COG1854	S-ribosylhomocysteine lyase activity
HZI73_RS19390	COG2195	Cleaves the N-terminal amino acid of tripeptides
HZI73_RS19395	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HZI73_RS19400	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
HZI73_RS19405	COG5002	protein histidine kinase activity
HZI73_RS19405	COG3850	Histidine kinase
HZI73_RS19410	COG0745	RESPONSE REGULATOR receiver
HZI73_RS19435	COG2207	Transcriptional regulator
HZI73_RS19435	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HZI73_RS19440	COG2972	Histidine kinase
HZI73_RS19450	COG0745	RESPONSE REGULATOR receiver
HZI73_RS19460	COG4608	Belongs to the ABC transporter superfamily
HZI73_RS19465	COG0444	Belongs to the ABC transporter superfamily
HZI73_RS19470	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HZI73_RS19475	COG0601	transmembrane transport
HZI73_RS19495	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HZI73_RS19500	COG0583	DNA-binding transcription factor activity
HZI73_RS19505	COG2226	methyltransferase
HZI73_RS19510	COG1028	Short-chain dehydrogenase reductase Sdr
HZI73_RS19545	COG3842	ATPase activity
HZI73_RS19550	COG3833	ABC-type maltose transport systems, permease component
HZI73_RS19555	COG1175	transmembrane transport
HZI73_RS19575	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HZI73_RS19595	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HZI73_RS19605	COG0542	response to heat
HZI73_RS19610	COG3869	Catalyzes the specific phosphorylation of arginine residues in
HZI73_RS19615	COG3880	PFAM UvrB UvrC protein
HZI73_RS19625	COG0785	Cytochrome C biogenesis protein
HZI73_RS19635	COG3859	Proton-coupled thiamine transporter YuaJ
HZI73_RS19660	COG0484	heat shock protein binding
HZI73_RS19725	COG1307	EDD domain protein, DegV family
HZI73_RS19750	COG0151	Belongs to the GarS family
HZI73_RS19755	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HZI73_RS19760	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
HZI73_RS19765	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HZI73_RS19775	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HZI73_RS19780	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HZI73_RS19830	COG0133	tryptophan synthase activity
HZI73_RS19835	COG0670	Belongs to the BI1 family
HZI73_RS19845	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HZI73_RS19865	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HZI73_RS19870	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HZI73_RS19875	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HZI73_RS19885	COG0697	spore germination
HZI73_RS19900	COG1307	EDD domain protein, DegV family
HZI73_RS19940	COG3858	chitin binding
HZI73_RS19940	COG1388	LysM domain
HZI73_RS19945	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HZI73_RS19950	COG1054	Belongs to the UPF0176 family
HZI73_RS19955	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HZI73_RS19960	COG4585	Histidine kinase
HZI73_RS19965	COG2197	response regulator
HZI73_RS19970	COG1131	(ABC) transporter
HZI73_RS19990	COG1725	Transcriptional regulator
HZI73_RS19995	COG1131	(ABC) transporter
HZI73_RS20010	COG1136	(ABC) transporter
HZI73_RS20020	COG0577	efflux transmembrane transporter activity
HZI73_RS20040	COG0697	spore germination
HZI73_RS20055	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HZI73_RS20060	COG1940	carbohydrate kinase activity
HZI73_RS20080	COG3250	beta-galactosidase activity
HZI73_RS20085	COG2972	Histidine kinase
HZI73_RS20090	COG2207	Transcriptional regulator
HZI73_RS20090	COG4753	response regulator
HZI73_RS20095	COG0395	ABC-type sugar transport system, permease component
HZI73_RS20110	COG0395	ABC-type sugar transport system, permease component
HZI73_RS20115	COG1175	transmembrane transport
HZI73_RS20120	COG2207	Transcriptional regulator
HZI73_RS20120	COG4753	response regulator
HZI73_RS20125	COG2972	Histidine kinase
HZI73_RS20150	COG0395	ABC-type sugar transport system, permease component
HZI73_RS20155	COG4209	transmembrane transport
HZI73_RS20160	COG2207	Transcriptional regulator
HZI73_RS20190	COG1349	DNA-binding transcription factor activity
HZI73_RS20195	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HZI73_RS20195	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HZI73_RS20195	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HZI73_RS20210	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HZI73_RS20215	COG1957	nucleoside hydrolase
HZI73_RS20230	COG0475	glutathione-regulated potassium exporter activity
HZI73_RS20255	COG0457	Tetratricopeptide repeat
HZI73_RS20260	COG1879	ABC-type sugar transport system periplasmic component
HZI73_RS20265	COG3279	Response regulator of the LytR AlgR family
HZI73_RS20270	COG2972	Histidine kinase
HZI73_RS20275	COG0457	Tetratricopeptide repeat
HZI73_RS20295	COG1129	ABC transporter
HZI73_RS20305	COG2207	Transcriptional regulator
HZI73_RS20305	COG3708	Transcriptional regulator
HZI73_RS20330	COG3409	Peptidoglycan-binding domain 1 protein
HZI73_RS20330	COG3773	Cell wall hydrolase
HZI73_RS20345	COG3409	Peptidoglycan-binding domain 1 protein
HZI73_RS20345	COG3773	Cell wall hydrolase
HZI73_RS20355	COG2197	response regulator
HZI73_RS20360	COG4585	Histidine kinase
HZI73_RS20365	COG1131	(ABC) transporter
HZI73_RS20380	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HZI73_RS20415	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HZI73_RS20420	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HZI73_RS20430	COG3958	Transketolase
HZI73_RS20435	COG3959	Transketolase, thiamine diphosphate binding domain
HZI73_RS20440	COG1028	Short-chain dehydrogenase reductase Sdr
HZI73_RS20445	COG1609	Transcriptional regulator
HZI73_RS20460	COG0746	molybdenum cofactor guanylyltransferase activity
HZI73_RS20480	COG0437	4 iron, 4 sulfur cluster binding
HZI73_RS20485	COG0243	molybdopterin cofactor binding
HZI73_RS20490	COG2390	Transcriptional regulator
HZI73_RS20500	COG1309	transcriptional regulator
HZI73_RS20525	COG0395	ABC-type sugar transport system, permease component
HZI73_RS20545	COG1132	(ABC) transporter
HZI73_RS20555	COG0789	Transcriptional regulator
HZI73_RS20555	COG4978	Transcriptional regulator
HZI73_RS20565	COG2378	regulation of single-species biofilm formation
HZI73_RS20575	COG0534	Mate efflux family protein
HZI73_RS20630	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HZI73_RS20645	COG1874	Beta-galactosidase
HZI73_RS20660	COG2376	Dihydroxyacetone kinase
HZI73_RS20665	COG1461	Dihydroxyacetone kinase
HZI73_RS20670	COG1082	Xylose isomerase domain protein TIM barrel
HZI73_RS20690	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HZI73_RS20695	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HZI73_RS20700	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HZI73_RS20710	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HZI73_RS20715	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HZI73_RS20750	COG1309	transcriptional regulator
HZI73_RS20775	COG2119	membrane
HZI73_RS20780	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HZI73_RS20785	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HZI73_RS20790	COG0426	domain, Protein
HZI73_RS20795	COG0697	spore germination
HZI73_RS20820	COG1609	Transcriptional regulator
HZI73_RS20825	COG1070	Carbohydrate kinase
HZI73_RS20830	COG1376	ErfK ybiS ycfS ynhG family protein
HZI73_RS20845	COG2211	Major facilitator Superfamily
HZI73_RS20850	COG3394	polysaccharide catabolic process
HZI73_RS20870	COG1285	pathogenesis
HZI73_RS20875	COG2205	protein histidine kinase activity
HZI73_RS20875	COG2770	Histidine kinase
HZI73_RS20880	COG0745	RESPONSE REGULATOR receiver
HZI73_RS20885	COG2207	Transcriptional regulator
HZI73_RS20885	COG1917	Cupin 2, conserved barrel domain protein
HZI73_RS20895	COG1132	(ABC) transporter
HZI73_RS20910	COG1683	Conserved Protein
HZI73_RS20915	COG0395	ABC-type sugar transport system, permease component
HZI73_RS20920	COG1175	transmembrane transport
HZI73_RS20930	COG3279	Response regulator of the LytR AlgR family
HZI73_RS20935	COG3275	phosphorelay sensor kinase activity
HZI73_RS20940	COG0514	ATP-dependent DNA helicase (RecQ)
HZI73_RS20975	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
HZI73_RS20990	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
HZI73_RS20995	COG0823	Involved in the tonB-independent uptake of proteins
HZI73_RS21005	COG4608	Belongs to the ABC transporter superfamily
HZI73_RS21010	COG0444	Belongs to the ABC transporter superfamily
HZI73_RS21015	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HZI73_RS21020	COG0601	transmembrane transport
HZI73_RS21025	COG0747	negative chemotaxis
HZI73_RS21040	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
HZI73_RS21060	COG1609	Transcriptional regulator
HZI73_RS21075	COG0395	ABC-type sugar transport system, permease component
HZI73_RS21080	COG4209	transmembrane transport
HZI73_RS21100	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HZI73_RS21100	COG1328	CTP reductase activity
HZI73_RS21105	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HZI73_RS21130	COG1120	ATPase activity
HZI73_RS21135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HZI73_RS21145	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HZI73_RS21185	COG1132	(ABC) transporter
HZI73_RS21190	COG1971	Probably functions as a manganese efflux pump
HZI73_RS21200	COG0277	FAD linked oxidase domain protein
HZI73_RS21205	COG1070	Carbohydrate kinase
HZI73_RS21230	COG0534	Mate efflux family protein
HZI73_RS21235	COG1028	Short-chain dehydrogenase reductase Sdr
HZI73_RS21240	COG1917	Cupin 2, conserved barrel domain protein
HZI73_RS21260	COG3842	ATPase activity
HZI73_RS21280	COG0395	ABC-type sugar transport system, permease component
HZI73_RS21285	COG4209	transmembrane transport
HZI73_RS21305	COG0697	spore germination
HZI73_RS21325	COG3119	arylsulfatase activity
HZI73_RS21340	COG3250	beta-galactosidase activity
HZI73_RS21350	COG1653	transport
HZI73_RS21355	COG0395	ABC-type sugar transport system, permease component
HZI73_RS21360	COG4209	transmembrane transport
HZI73_RS21370	COG3250	beta-galactosidase activity
HZI73_RS21400	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HZI73_RS21410	COG1876	peptidase activity
HZI73_RS21415	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HZI73_RS21425	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HZI73_RS21435	COG1609	Transcriptional regulator
HZI73_RS21440	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HZI73_RS21445	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HZI73_RS21465	COG3119	arylsulfatase activity
HZI73_RS21485	COG3459	Glycosyltransferase 36 associated
HZI73_RS21495	COG0395	ABC-type sugar transport system, permease component
HZI73_RS21500	COG4209	transmembrane transport
HZI73_RS21505	COG2201	protein-glutamate methylesterase activity
HZI73_RS21510	COG2972	Histidine kinase
HZI73_RS21525	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HZI73_RS21530	COG2226	methyltransferase
HZI73_RS21550	COG0673	inositol 2-dehydrogenase activity
HZI73_RS21570	COG1074	ATP-dependent DNA helicase activity
HZI73_RS21580	COG0383	alpha-mannosidase activity
HZI73_RS21590	COG3842	ATPase activity
HZI73_RS21600	COG1175	transmembrane transport
HZI73_RS21615	COG1472	Belongs to the glycosyl hydrolase 3 family
HZI73_RS21620	COG2207	Transcriptional regulator
HZI73_RS21630	COG0523	cobalamin synthesis protein
HZI73_RS21660	COG1309	transcriptional regulator
HZI73_RS21665	COG0596	Alpha beta hydrolase
HZI73_RS21670	COG1394	ATPase activity, coupled to movement of substances
HZI73_RS21700	COG1269	ATP hydrolysis coupled proton transport
HZI73_RS21720	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
HZI73_RS21775	COG1597	lipid kinase activity
HZI73_RS21790	COG1388	LysM domain
HZI73_RS21790	COG4641	Protein conserved in bacteria
HZI73_RS21800	COG0438	transferase activity, transferring glycosyl groups
HZI73_RS21805	COG0457	Tetratricopeptide repeat
HZI73_RS21805	COG0463	Glycosyl transferase, family 2
HZI73_RS21810	COG1653	transport
HZI73_RS21815	COG0395	ABC-type sugar transport system, permease component
HZI73_RS21820	COG4209	transmembrane transport
HZI73_RS21825	COG2207	Transcriptional regulator
HZI73_RS21835	COG2972	Histidine kinase
HZI73_RS21845	COG0395	ABC-type sugar transport system, permease component
HZI73_RS21850	COG4209	transmembrane transport
HZI73_RS21855	COG1653	transport
HZI73_RS21875	COG1216	Glycosyl transferase, family 2
HZI73_RS21895	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HZI73_RS21915	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HZI73_RS21920	COG1091	dTDP-4-dehydrorhamnose reductase activity
HZI73_RS21930	COG1331	Highly conserved protein containing a thioredoxin domain
HZI73_RS21945	COG4608	Belongs to the ABC transporter superfamily
HZI73_RS21950	COG0444	Belongs to the ABC transporter superfamily
HZI73_RS21955	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HZI73_RS21960	COG0601	transmembrane transport
HZI73_RS21965	COG4166	transmembrane transport
HZI73_RS21975	COG2207	Transcriptional regulator
HZI73_RS21975	COG4753	response regulator
HZI73_RS21980	COG1361	Conserved repeat domain
HZI73_RS21980	COG2911	Protein conserved in bacteria
HZI73_RS21980	COG3266	domain, Protein
HZI73_RS21990	COG0395	ABC-type sugar transport system, permease component
HZI73_RS21995	COG1175	transmembrane transport
HZI73_RS22000	COG4753	response regulator
HZI73_RS22000	COG2207	Transcriptional regulator
HZI73_RS22005	COG2972	Histidine kinase
HZI73_RS22015	COG4608	Belongs to the ABC transporter superfamily
HZI73_RS22020	COG0444	Belongs to the ABC transporter superfamily
HZI73_RS22025	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HZI73_RS22065	COG0662	Cupin 2, conserved barrel domain protein
HZI73_RS22065	COG2207	Transcriptional regulator
HZI73_RS22080	COG1131	(ABC) transporter
HZI73_RS22105	COG1012	belongs to the aldehyde dehydrogenase family
HZI73_RS22110	COG4948	Mandelate Racemase Muconate Lactonizing
HZI73_RS22120	COG1802	Transcriptional regulator
HZI73_RS22125	COG1082	Xylose isomerase domain protein TIM barrel
HZI73_RS22150	COG1129	ABC transporter
HZI73_RS22155	COG1609	Transcriptional regulator
HZI73_RS22165	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
HZI73_RS22190	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HZI73_RS22195	COG1063	alcohol dehydrogenase
HZI73_RS22205	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HZI73_RS22220	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HZI73_RS22285	COG4974	Belongs to the 'phage' integrase family
HZI73_RS22410	COG0740	serine-type endopeptidase activity
HZI73_RS22490	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HZI73_RS22555	COG4974	Belongs to the 'phage' integrase family
HZI73_RS22640	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
HZI73_RS22645	COG1528	Iron-storage protein
HZI73_RS22660	COG1234	tRNA 3'-trailer cleavage
HZI73_RS22670	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HZI73_RS22675	COG1067	ATP-dependent peptidase activity
HZI73_RS22690	COG0456	acetyltransferase
HZI73_RS22695	COG1214	PFAM Peptidase M22, glycoprotease
HZI73_RS22700	COG0802	atpase or kinase
HZI73_RS22710	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HZI73_RS22725	COG1950	PFAM Membrane protein of
HZI73_RS22750	COG2183	response to ionizing radiation
HZI73_RS22755	COG0395	ABC-type sugar transport system, permease component
HZI73_RS22760	COG1175	transmembrane transport
HZI73_RS22770	COG4753	response regulator
HZI73_RS22770	COG2207	Transcriptional regulator
HZI73_RS22775	COG2972	Histidine kinase
HZI73_RS22785	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
HZI73_RS22790	COG0460	homoserine dehydrogenase
HZI73_RS22795	COG4492	Belongs to the UPF0735 family
HZI73_RS22800	COG0835	chemotaxis
HZI73_RS22810	COG0653	protein targeting
HZI73_RS22835	COG1070	Carbohydrate kinase
HZI73_RS22840	COG4154	Belongs to the RbsD FucU family
HZI73_RS22845	COG1105	Belongs to the carbohydrate kinase PfkB family
HZI73_RS22855	COG1063	alcohol dehydrogenase
HZI73_RS22860	COG0656	L-ascorbic acid biosynthetic process
HZI73_RS22875	COG4989	oxidoreductase activity
HZI73_RS22880	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HZI73_RS22885	COG2210	Belongs to the sulfur carrier protein TusA family
HZI73_RS22925	COG0556	nucleotide-excision repair
HZI73_RS22930	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HZI73_RS22935	COG0793	Belongs to the peptidase S41A family
HZI73_RS22935	COG3409	Peptidoglycan-binding domain 1 protein
HZI73_RS22940	COG0739	heme binding
HZI73_RS22940	COG0741	lytic transglycosylase activity
HZI73_RS22940	COG1196	nuclear chromosome segregation
HZI73_RS22945	COG2177	Part of the ABC transporter FtsEX involved in
HZI73_RS22950	COG2884	Cell division ATP-binding protein ftsE
HZI73_RS22955	COG3835	regulator
HZI73_RS22960	COG3842	ATPase activity
HZI73_RS22965	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HZI73_RS23000	COG0297	glycogen (starch) synthase activity
HZI73_RS23020	COG0110	maltose O-acetyltransferase activity
HZI73_RS23040	COG1316	TRANSCRIPTIONal
HZI73_RS23045	COG1316	TRANSCRIPTIONal
HZI73_RS23055	COG1028	Short-chain dehydrogenase reductase Sdr
HZI73_RS23070	COG0489	protein tyrosine kinase activity
HZI73_RS23075	COG3944	biosynthesis protein
HZI73_RS23080	COG4464	protein tyrosine phosphatase activity
HZI73_RS23120	COG0728	peptidoglycan biosynthetic process
HZI73_RS23125	COG0438	transferase activity, transferring glycosyl groups
HZI73_RS23140	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
HZI73_RS23150	COG2089	acid synthase
HZI73_RS23165	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HZI73_RS23170	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HZI73_RS23180	COG1216	Glycosyl transferase, family 2
HZI73_RS23180	COG0463	Glycosyl transferase, family 2
HZI73_RS23185	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HZI73_RS23205	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HZI73_RS23210	COG1481	regulation of sporulation
HZI73_RS23225	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HZI73_RS23235	COG2190	(PTS) system
HZI73_RS23235	COG2211	Major facilitator Superfamily
HZI73_RS23275	COG2814	Major facilitator Superfamily
HZI73_RS23280	COG2313	pseudouridylate synthase activity
HZI73_RS23285	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HZI73_RS23300	COG1940	carbohydrate kinase activity
HZI73_RS23310	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
HZI73_RS23315	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HZI73_RS23320	COG1473	amidohydrolase
HZI73_RS23325	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HZI73_RS23330	COG0402	S-adenosylhomocysteine deaminase activity
HZI73_RS23340	COG1957	nucleoside hydrolase
HZI73_RS23345	COG1079	Belongs to the binding-protein-dependent transport system permease family
HZI73_RS23350	COG4603	Belongs to the binding-protein-dependent transport system permease family
HZI73_RS23355	COG3845	ABC transporter
HZI73_RS23360	COG1744	ABC transporter substrate-binding protein PnrA-like
HZI73_RS23390	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HZI73_RS23400	COG0156	8-amino-7-oxononanoate synthase activity
HZI73_RS23405	COG0006	proline dipeptidase activity
HZI73_RS23435	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HZI73_RS23440	COG0322	excinuclease ABC activity
HZI73_RS23445	COG1132	(ABC) transporter
HZI73_RS23450	COG1132	(ABC) transporter
HZI73_RS23460	COG0668	transmembrane transport
HZI73_RS23465	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HZI73_RS23510	COG1486	melibiose metabolic process
HZI73_RS23530	COG0210	DNA helicase
HZI73_RS23535	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
HZI73_RS23590	COG3279	Response regulator of the LytR AlgR family
HZI73_RS23685	COG0739	heme binding
HZI73_RS23720	COG3290	protein histidine kinase activity
HZI73_RS23735	COG1028	Short-chain dehydrogenase reductase Sdr
HZI73_RS23750	COG0488	(ABC) transporter
HZI73_RS23765	COG0588	phosphoglycerate mutase activity
HZI73_RS23770	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
HZI73_RS23775	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
HZI73_RS23780	COG1073	alpha beta
HZI73_RS23800	COG1522	sequence-specific DNA binding
HZI73_RS23805	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
HZI73_RS23810	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HZI73_RS23810	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HZI73_RS23815	COG0307	riboflavin synthase, alpha
HZI73_RS23825	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HZI73_RS23830	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
HZI73_RS23845	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HZI73_RS23850	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HZI73_RS23865	COG4977	sequence-specific DNA binding
HZI73_RS23865	COG1917	Cupin 2, conserved barrel domain protein
HZI73_RS23870	COG2217	Heavy metal translocating P-type atpase
HZI73_RS23875	COG0640	Transcriptional regulator
HZI73_RS23880	COG5002	protein histidine kinase activity
HZI73_RS23885	COG0745	RESPONSE REGULATOR receiver
HZI73_RS23900	COG2223	nitrite transmembrane transporter activity
HZI73_RS23925	COG0651	ATP synthesis coupled electron transport
HZI73_RS23950	COG1309	transcriptional regulator
HZI73_RS23980	COG1609	Transcriptional regulator
HZI73_RS24000	COG2897	thiosulfate sulfurtransferase activity
HZI73_RS24010	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HZI73_RS24020	COG1181	Belongs to the D-alanine--D-alanine ligase family
HZI73_RS24030	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HZI73_RS24045	COG2391	methyltransferase activity
HZI73_RS24060	COG2391	methyltransferase activity
HZI73_RS24080	COG0708	Exodeoxyribonuclease III
HZI73_RS24110	COG0673	inositol 2-dehydrogenase activity
HZI73_RS24125	COG1511	domain protein
HZI73_RS24125	COG0842	Transport permease protein
HZI73_RS24130	COG1131	(ABC) transporter
HZI73_RS24140	COG2197	response regulator
HZI73_RS24145	COG4585	Histidine kinase
HZI73_RS24155	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
HZI73_RS24160	COG3119	arylsulfatase activity
HZI73_RS24165	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HZI73_RS24165	COG2207	Transcriptional regulator
HZI73_RS24170	COG1574	metal-dependent hydrolase with the TIM-barrel fold
HZI73_RS24210	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
HZI73_RS24225	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HZI73_RS24280	COG1309	transcriptional regulator
HZI73_RS24290	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HZI73_RS24300	COG3507	Belongs to the glycosyl hydrolase 43 family
HZI73_RS24305	COG3386	PFAM SMP-30 Gluconolaconase
HZI73_RS24310	COG1942	4-Oxalocrotonate Tautomerase
HZI73_RS24325	COG1733	regulation of RNA biosynthetic process
HZI73_RS24335	COG4608	Belongs to the ABC transporter superfamily
HZI73_RS24340	COG0444	Belongs to the ABC transporter superfamily
HZI73_RS24350	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HZI73_RS24355	COG0601	transmembrane transport
HZI73_RS24380	COG0800	Aldolase
HZI73_RS24390	COG0395	ABC-type sugar transport system, permease component
HZI73_RS24395	COG1175	transmembrane transport
HZI73_RS24410	COG4753	response regulator
HZI73_RS24410	COG2207	Transcriptional regulator
HZI73_RS24415	COG2972	Histidine kinase
HZI73_RS24430	COG3119	arylsulfatase activity
HZI73_RS24435	COG0395	ABC-type sugar transport system, permease component
HZI73_RS24440	COG4209	transmembrane transport
HZI73_RS24455	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HZI73_RS24460	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HZI73_RS24470	COG3885	ferrous iron binding
HZI73_RS24470	COG2078	PFAM AMMECR1 domain protein
HZI73_RS24480	COG0300	oxidoreductase activity
HZI73_RS24515	COG2207	Transcriptional regulator
HZI73_RS24515	COG4753	response regulator
HZI73_RS24520	COG2972	Histidine kinase
HZI73_RS24530	COG0395	ABC-type sugar transport system, permease component
HZI73_RS24535	COG1175	transmembrane transport
HZI73_RS24550	COG3708	Transcriptional regulator
HZI73_RS24550	COG2207	Transcriptional regulator
HZI73_RS24565	COG2205	protein histidine kinase activity
HZI73_RS24565	COG0745	RESPONSE REGULATOR receiver
HZI73_RS24565	COG3292	Two component regulator propeller
HZI73_RS24575	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HZI73_RS24585	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HZI73_RS24605	COG1070	Carbohydrate kinase
HZI73_RS24610	COG0235	Class ii aldolase
HZI73_RS24615	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HZI73_RS24620	COG0022	dehydrogenase e1 component
HZI73_RS24625	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HZI73_RS24630	COG3119	arylsulfatase activity
HZI73_RS24645	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HZI73_RS24650	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HZI73_RS24670	COG1653	transport
HZI73_RS24675	COG0395	ABC-type sugar transport system, permease component
HZI73_RS24680	COG4209	transmembrane transport
HZI73_RS24710	COG2207	Transcriptional regulator
HZI73_RS24710	COG1917	Cupin 2, conserved barrel domain protein
HZI73_RS24765	COG0534	Mate efflux family protein
HZI73_RS24790	COG4608	Belongs to the ABC transporter superfamily
HZI73_RS24800	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HZI73_RS24805	COG0601	transmembrane transport
HZI73_RS24815	COG0191	fructose-bisphosphate aldolase activity
HZI73_RS24825	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HZI73_RS24835	COG3119	arylsulfatase activity
HZI73_RS24860	COG0747	negative chemotaxis
HZI73_RS24870	COG1819	glycosyl
HZI73_RS24905	COG3119	arylsulfatase activity
HZI73_RS24915	COG0395	ABC-type sugar transport system, permease component
HZI73_RS24920	COG4209	transmembrane transport
HZI73_RS24925	COG1653	transport
HZI73_RS24935	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HZI73_RS24940	COG4120	Belongs to the binding-protein-dependent transport system permease family
HZI73_RS24970	COG3842	ATPase activity
HZI73_RS24975	COG3833	ABC-type maltose transport systems, permease component
HZI73_RS25035	COG0395	ABC-type sugar transport system, permease component
HZI73_RS25040	COG4209	transmembrane transport
HZI73_RS25045	COG3275	phosphorelay sensor kinase activity
HZI73_RS25050	COG2207	Transcriptional regulator
HZI73_RS25055	COG1509	lysine 2,3-aminomutase activity
HZI73_RS25070	COG0789	Transcriptional regulator
HZI73_RS25085	COG1129	ABC transporter
HZI73_RS25090	COG1172	Belongs to the binding-protein-dependent transport system permease family
HZI73_RS25125	COG1028	Short-chain dehydrogenase reductase Sdr
HZI73_RS25135	COG1653	transport
HZI73_RS25140	COG0395	ABC-type sugar transport system, permease component
HZI73_RS25145	COG4209	transmembrane transport
HZI73_RS25155	COG0667	Aldo Keto reductase
HZI73_RS25165	COG3459	Glycosyltransferase 36 associated
HZI73_RS25170	COG0395	ABC-type sugar transport system, permease component
HZI73_RS25175	COG1175	transmembrane transport
HZI73_RS25180	COG1653	transport
HZI73_RS25190	COG3275	phosphorelay sensor kinase activity
HZI73_RS25205	COG1501	Belongs to the glycosyl hydrolase 31 family
HZI73_RS25210	COG3275	phosphorelay sensor kinase activity
HZI73_RS25215	COG3279	Response regulator of the LytR AlgR family
HZI73_RS25225	COG0395	ABC-type sugar transport system, permease component
HZI73_RS25230	COG4209	transmembrane transport
HZI73_RS25250	COG0210	DNA helicase
HZI73_RS25285	COG2207	Transcriptional regulator
HZI73_RS25285	COG3708	Transcriptional regulator
HZI73_RS25300	COG2378	regulation of single-species biofilm formation
HZI73_RS25305	COG2267	carboxylic ester hydrolase activity
HZI73_RS25325	COG1028	Short-chain dehydrogenase reductase Sdr
HZI73_RS25330	COG0534	Mate efflux family protein
HZI73_RS25335	COG3119	arylsulfatase activity
HZI73_RS25340	COG4209	transmembrane transport
HZI73_RS25345	COG0395	ABC-type sugar transport system, permease component
HZI73_RS25405	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HZI73_RS25410	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HZI73_RS25415	COG3481	metal-dependent phosphohydrolase, HD sub domain
HZI73_RS25435	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HZI73_RS25445	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HZI73_RS25450	COG1028	Short-chain dehydrogenase reductase Sdr
HZI73_RS25455	COG1063	alcohol dehydrogenase
HZI73_RS25465	COG2972	Histidine kinase
HZI73_RS25480	COG1172	Belongs to the binding-protein-dependent transport system permease family
HZI73_RS25485	COG1879	ABC-type sugar transport system periplasmic component
HZI73_RS25490	COG1172	Belongs to the binding-protein-dependent transport system permease family
HZI73_RS25495	COG1129	ABC transporter
HZI73_RS25505	COG1024	Enoyl-CoA hydratase
HZI73_RS25515	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HZI73_RS25525	COG3250	beta-galactosidase activity
HZI73_RS25530	COG3250	beta-galactosidase activity
HZI73_RS25550	COG0395	ABC-type sugar transport system, permease component
HZI73_RS25555	COG4209	transmembrane transport
HZI73_RS25565	COG2207	Transcriptional regulator
HZI73_RS25570	COG0739	heme binding
HZI73_RS25590	COG1193	negative regulation of DNA recombination
HZI73_RS25595	COG0745	RESPONSE REGULATOR receiver
HZI73_RS25600	COG5002	protein histidine kinase activity
HZI73_RS25605	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HZI73_RS25620	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
HZI73_RS25655	COG0735	belongs to the Fur family
HZI73_RS25660	COG0436	Aminotransferase
HZI73_RS25665	COG1522	sequence-specific DNA binding
HZI73_RS25675	COG2720	vancomycin resistance protein
HZI73_RS25685	COG2373	Large extracellular alpha-helical protein
HZI73_RS25690	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
HZI73_RS25695	COG1605	Chorismate mutase
HZI73_RS25695	COG0077	Prephenate dehydratase
HZI73_RS25720	COG0572	uridine kinase
HZI73_RS25735	COG0395	ABC-type sugar transport system, permease component
HZI73_RS25740	COG1175	transmembrane transport
HZI73_RS25745	COG1653	transport
HZI73_RS25750	COG2207	Transcriptional regulator
HZI73_RS25750	COG4753	response regulator
HZI73_RS25755	COG2972	Histidine kinase
HZI73_RS25760	COG2207	Transcriptional regulator
HZI73_RS25770	COG0494	nUDIX hydrolase
HZI73_RS25775	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HZI73_RS25790	COG1376	ErfK ybiS ycfS ynhG family protein
HZI73_RS25850	COG1136	(ABC) transporter
HZI73_RS25855	COG0577	efflux transmembrane transporter activity
HZI73_RS25865	COG1785	Belongs to the alkaline phosphatase family
HZI73_RS25875	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
HZI73_RS25880	COG0789	Transcriptional regulator
HZI73_RS25910	COG3778	Protein conserved in bacteria
HZI73_RS25915	COG3299	homolog of phage Mu protein gp47
HZI73_RS25935	COG1652	LysM domain
HZI73_RS26015	COG1131	(ABC) transporter
HZI73_RS26040	COG2197	response regulator
HZI73_RS26045	COG2207	Transcriptional regulator
HZI73_RS26160	COG0629	single-stranded DNA binding
HZI73_RS26170	COG2003	Belongs to the UPF0758 family
HZI73_RS26210	COG3451	type IV secretory pathway VirB4
HZI73_RS26220	COG0739	heme binding
HZI73_RS26235	COG4962	Type ii secretion system protein e
HZI73_RS26295	COG1361	Conserved repeat domain
HZI73_RS26310	COG1361	Conserved repeat domain
HZI73_RS26320	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HZI73_RS26465	COG2801	Transposase and inactivated derivatives
HZI73_RS26480	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HZI73_RS26485	COG1174	glycine betaine transport
HZI73_RS26520	COG2340	Cysteine-rich secretory protein family
HZI73_RS26525	COG0840	transmembrane signaling receptor activity
HZI73_RS26555	COG2207	Transcriptional regulator
HZI73_RS26570	COG1690	Belongs to the RtcB family