locus-tag	class	description
CKY39_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CKY39_RS00010	COG0592	DNA-directed DNA polymerase activity
CKY39_RS00045	COG0392	lysyltransferase activity
CKY39_RS00050	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CKY39_RS00055	COG3568	Endonuclease Exonuclease Phosphatase
CKY39_RS00080	COG0456	acetyltransferase
CKY39_RS00080	COG0454	-acetyltransferase
CKY39_RS00085	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CKY39_RS00105	COG4452	Inner membrane protein CreD
CKY39_RS00110	COG1472	Belongs to the glycosyl hydrolase 3 family
CKY39_RS00125	COG2205	protein histidine kinase activity
CKY39_RS00130	COG0745	RESPONSE REGULATOR receiver
CKY39_RS00145	COG2608	mercury ion transmembrane transporter activity
CKY39_RS00150	COG2217	Heavy metal translocating P-type atpase
CKY39_RS00175	COG0745	RESPONSE REGULATOR receiver
CKY39_RS00185	COG0456	acetyltransferase
CKY39_RS00205	COG1024	Enoyl-CoA hydratase
CKY39_RS00225	COG0445	tRNA wobble uridine modification
CKY39_RS00230	COG0357	Ribosomal RNA small subunit methyltransferase G
CKY39_RS00240	COG1192	Involved in chromosome partitioning
CKY39_RS00250	COG1475	DNA binding
CKY39_RS00260	COG0277	FAD linked oxidase domain protein
CKY39_RS00270	COG2096	Adenosyltransferase
CKY39_RS00350	COG0583	DNA-binding transcription factor activity
CKY39_RS00370	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CKY39_RS00375	COG2894	cell division
CKY39_RS00385	COG2233	PERMEase
CKY39_RS00415	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CKY39_RS00430	COG1250	3-hydroxyacyl-CoA dehydrogenase
CKY39_RS00440	COG3246	L-lysine catabolic process to acetate
CKY39_RS00460	COG1309	transcriptional regulator
CKY39_RS00465	COG1819	glycosyl
CKY39_RS00470	COG3284	Transcriptional regulator
CKY39_RS00475	COG1942	4-Oxalocrotonate Tautomerase
CKY39_RS00480	COG1028	Short-chain dehydrogenase reductase Sdr
CKY39_RS00535	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CKY39_RS00565	COG1959	2 iron, 2 sulfur cluster binding
CKY39_RS00570	COG3634	alkyl hydroperoxide reductase activity
CKY39_RS00585	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CKY39_RS00590	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CKY39_RS00595	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CKY39_RS00600	COG1116	anion transmembrane transporter activity
CKY39_RS00600	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CKY39_RS00615	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CKY39_RS00625	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CKY39_RS00640	COG2207	Transcriptional regulator
CKY39_RS00645	COG0583	DNA-binding transcription factor activity
CKY39_RS00650	COG1960	acyl-CoA dehydrogenase activity
CKY39_RS00655	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CKY39_RS00670	COG0583	DNA-binding transcription factor activity
CKY39_RS00680	COG1473	amidohydrolase
CKY39_RS00685	COG1760	l-serine dehydratase
CKY39_RS00700	COG1573	uracil-dna glycosylase
CKY39_RS00715	COG0583	DNA-binding transcription factor activity
CKY39_RS00740	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CKY39_RS00745	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CKY39_RS00755	COG1129	ABC transporter
CKY39_RS00760	COG0559	Belongs to the binding-protein-dependent transport system permease family
CKY39_RS00790	COG2066	Belongs to the glutaminase family
CKY39_RS00805	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CKY39_RS00835	COG2015	COG2015, Alkyl sulfatase and related hydrolases
CKY39_RS00840	COG0700	Nucleoside recognition
CKY39_RS00845	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CKY39_RS00860	COG0410	ABC transporter
CKY39_RS00880	COG0683	leucine binding
CKY39_RS00885	COG0633	Ferredoxin
CKY39_RS00945	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
CKY39_RS00950	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CKY39_RS00955	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CKY39_RS00970	COG1070	Carbohydrate kinase
CKY39_RS00990	COG0514	ATP-dependent DNA helicase (RecQ)
CKY39_RS01000	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CKY39_RS01005	COG1116	anion transmembrane transporter activity
CKY39_RS01015	COG2986	histidine ammonia-lyase
CKY39_RS01020	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CKY39_RS01035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CKY39_RS01040	COG0765	amino acid transport
CKY39_RS01050	COG1228	amidohydrolase
CKY39_RS01065	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CKY39_RS01090	COG5380	lipid catabolic process
CKY39_RS01095	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CKY39_RS01100	COG0646	methionine synthase
CKY39_RS01100	COG1410	methionine synthase
CKY39_RS01125	COG1309	transcriptional regulator
CKY39_RS01155	COG0683	leucine binding
CKY39_RS01175	COG1335	isochorismatase
CKY39_RS01185	COG2080	2 iron, 2 sulfur cluster binding
CKY39_RS01190	COG2010	Cytochrome c
CKY39_RS01190	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CKY39_RS01330	COG0347	Belongs to the P(II) protein family
CKY39_RS01335	COG0004	ammonium transporteR
CKY39_RS01345	COG0583	DNA-binding transcription factor activity
CKY39_RS01350	COG1620	l-lactate permease
CKY39_RS01355	COG0277	FAD linked oxidase domain protein
CKY39_RS01360	COG0277	FAD linked oxidase domain protein
CKY39_RS01365	COG0247	lactate metabolic process
CKY39_RS01375	COG0386	Belongs to the glutathione peroxidase family
CKY39_RS01385	COG0477	Major facilitator Superfamily
CKY39_RS01390	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CKY39_RS01410	COG0217	transcriptional regulatory protein
CKY39_RS01420	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CKY39_RS01435	COG0129	dihydroxy-acid dehydratase activity
CKY39_RS01470	COG3181	Tripartite tricarboxylate transporter family receptor
CKY39_RS01475	COG1012	belongs to the aldehyde dehydrogenase family
CKY39_RS01495	COG1846	Transcriptional regulator
CKY39_RS01520	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CKY39_RS01540	COG2974	May be involved in recombination
CKY39_RS01565	COG0745	RESPONSE REGULATOR receiver
CKY39_RS01575	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CKY39_RS01580	COG2211	Major facilitator Superfamily
CKY39_RS01585	COG0501	Belongs to the peptidase M48B family
CKY39_RS01600	COG0583	DNA-binding transcription factor activity
CKY39_RS01620	COG0708	Exodeoxyribonuclease III
CKY39_RS01625	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CKY39_RS01635	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CKY39_RS01640	COG0154	amidase activity
CKY39_RS01645	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CKY39_RS01650	COG1077	Cell shape determining protein MreB Mrl
CKY39_RS01655	COG1792	Involved in formation and maintenance of cell shape
CKY39_RS01665	COG0768	penicillin binding
CKY39_RS01670	COG0179	Fumarylacetoacetate (FAA) hydrolase
CKY39_RS01680	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CKY39_RS01690	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CKY39_RS01705	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CKY39_RS01730	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CKY39_RS01735	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CKY39_RS01740	COG0583	DNA-binding transcription factor activity
CKY39_RS01775	COG0436	Aminotransferase
CKY39_RS01780	COG0028	Belongs to the TPP enzyme family
CKY39_RS01790	COG0004	ammonium transporteR
CKY39_RS01820	COG0023	Translation Initiation Factor
CKY39_RS01825	COG0513	Belongs to the DEAD box helicase family
CKY39_RS01830	COG0330	HflC and HflK could
CKY39_RS01835	COG1960	acyl-CoA dehydrogenase activity
CKY39_RS01840	COG1960	acyl-CoA dehydrogenase activity
CKY39_RS01845	COG1028	Short-chain dehydrogenase reductase Sdr
CKY39_RS01850	COG0439	Biotin carboxylase
CKY39_RS01855	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CKY39_RS01870	COG2733	membrane
CKY39_RS01880	COG0584	glycerophosphoryl diester phosphodiesterase
CKY39_RS01885	COG1473	amidohydrolase
CKY39_RS01900	COG0243	molybdopterin cofactor binding
CKY39_RS01915	COG1028	Short-chain dehydrogenase reductase Sdr
CKY39_RS01920	COG1070	Carbohydrate kinase
CKY39_RS01925	COG1063	alcohol dehydrogenase
CKY39_RS01930	COG1172	Belongs to the binding-protein-dependent transport system permease family
CKY39_RS01935	COG1129	ABC transporter
CKY39_RS01940	COG1879	ABC-type sugar transport system periplasmic component
CKY39_RS01945	COG4977	sequence-specific DNA binding
CKY39_RS01950	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CKY39_RS01995	COG0583	DNA-binding transcription factor activity
CKY39_RS02010	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CKY39_RS02020	COG3181	Tripartite tricarboxylate transporter family receptor
CKY39_RS02025	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CKY39_RS02050	COG1028	Short-chain dehydrogenase reductase Sdr
CKY39_RS02060	COG1129	ABC transporter
CKY39_RS02100	COG0667	Aldo Keto reductase
CKY39_RS02105	COG1172	Belongs to the binding-protein-dependent transport system permease family
CKY39_RS02120	COG1070	Carbohydrate kinase
CKY39_RS02125	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CKY39_RS02130	COG2188	Transcriptional regulator
CKY39_RS02155	COG0629	single-stranded DNA binding
CKY39_RS02160	COG0436	Aminotransferase
CKY39_RS02170	COG1028	Short-chain dehydrogenase reductase Sdr
CKY39_RS02175	COG4598	ABC transporter
CKY39_RS02230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CKY39_RS02235	COG0318	PFAM AMP-dependent synthetase and ligase
CKY39_RS02240	COG0482	sulfurtransferase activity
CKY39_RS02265	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CKY39_RS02280	COG0318	PFAM AMP-dependent synthetase and ligase
CKY39_RS02285	COG0601	transmembrane transport
CKY39_RS02290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CKY39_RS02295	COG0444	Belongs to the ABC transporter superfamily
CKY39_RS02305	COG0747	negative chemotaxis
CKY39_RS02320	COG0598	Magnesium transport protein CorA
CKY39_RS02330	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CKY39_RS02340	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CKY39_RS02345	COG0735	belongs to the Fur family
CKY39_RS02350	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CKY39_RS02355	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CKY39_RS02370	COG0058	SHG alpha-glucan phosphorylase activity
CKY39_RS02375	COG0297	glycogen (starch) synthase activity
CKY39_RS02380	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CKY39_RS02400	COG0366	Alpha amylase catalytic
CKY39_RS02405	COG2072	flavoprotein involved in K transport
CKY39_RS02410	COG0495	leucyl-tRNA aminoacylation
CKY39_RS02425	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CKY39_RS02440	COG3135	benzoate transporter
CKY39_RS02445	COG0189	ligase activity
CKY39_RS02455	COG0121	glutamine amidotransferase
CKY39_RS02470	COG1079	Belongs to the binding-protein-dependent transport system permease family
CKY39_RS02495	COG3181	Tripartite tricarboxylate transporter family receptor
CKY39_RS02500	COG0154	amidase activity
CKY39_RS02525	COG5441	Belongs to the UPF0261 family
CKY39_RS02535	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CKY39_RS02560	COG2814	Major facilitator Superfamily
CKY39_RS02575	COG0205	6-phosphofructokinase activity
CKY39_RS02585	COG1024	Enoyl-CoA hydratase
CKY39_RS02595	COG0583	DNA-binding transcription factor activity
CKY39_RS02600	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CKY39_RS02620	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CKY39_RS02625	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CKY39_RS02630	COG3181	Tripartite tricarboxylate transporter family receptor
CKY39_RS02635	COG1414	Transcriptional regulator
CKY39_RS02640	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CKY39_RS02645	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CKY39_RS02650	COG0583	DNA-binding transcription factor activity
CKY39_RS02665	COG0018	arginyl-trna synthetase
CKY39_RS02675	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CKY39_RS02680	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CKY39_RS02685	COG1137	ATPase activity
CKY39_RS02695	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CKY39_RS02705	COG1280	lysine exporter protein (LysE YggA)
CKY39_RS02715	COG2353	YceI-like domain
CKY39_RS02735	COG2076	Multidrug Resistance protein
CKY39_RS02760	COG0069	glutamate synthase activity
CKY39_RS02785	COG2197	response regulator
CKY39_RS02800	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CKY39_RS02810	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CKY39_RS02815	COG3181	Tripartite tricarboxylate transporter family receptor
CKY39_RS02820	COG0583	DNA-binding transcription factor activity
CKY39_RS02845	COG1335	isochorismatase
CKY39_RS02850	COG4977	sequence-specific DNA binding
CKY39_RS02855	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CKY39_RS02870	COG2967	ApaG domain
CKY39_RS02875	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CKY39_RS02925	COG5002	protein histidine kinase activity
CKY39_RS02940	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CKY39_RS02945	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CKY39_RS02985	COG0515	serine threonine protein kinase
CKY39_RS03125	COG0546	phosphoglycolate phosphatase activity
CKY39_RS03155	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CKY39_RS03160	COG0134	indole-3-glycerol-phosphate synthase activity
CKY39_RS03165	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CKY39_RS03185	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CKY39_RS03195	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CKY39_RS03205	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CKY39_RS03210	COG0081	regulation of translation
CKY39_RS03215	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CKY39_RS03220	COG0222	ribosome binding
CKY39_RS03225	COG0085	RNA polymerase activity
CKY39_RS03230	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CKY39_RS03250	COG5000	phosphorelay sensor kinase activity
CKY39_RS03255	COG2204	response regulator
CKY39_RS03350	COG1404	Belongs to the peptidase S8 family
CKY39_RS03355	COG1537	nuclear-transcribed mRNA catabolic process, no-go decay
CKY39_RS03385	COG0582	viral genome integration into host DNA
CKY39_RS03435	COG3121	Chaperone
CKY39_RS03440	COG3539	Fimbrial protein
CKY39_RS03450	COG3121	Chaperone
CKY39_RS03470	COG2207	Transcriptional regulator
CKY39_RS03485	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CKY39_RS03500	COG0210	DNA helicase
CKY39_RS03505	COG0679	Auxin Efflux Carrier
CKY39_RS03525	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CKY39_RS03530	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CKY39_RS03580	COG1129	ABC transporter
CKY39_RS03585	COG0583	DNA-binding transcription factor activity
CKY39_RS03600	COG4977	sequence-specific DNA binding
CKY39_RS03600	COG1917	Cupin 2, conserved barrel domain protein
CKY39_RS03610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CKY39_RS03615	COG4232	protein-disulfide reductase activity
CKY39_RS03620	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CKY39_RS03640	COG0583	DNA-binding transcription factor activity
CKY39_RS03650	COG1028	Short-chain dehydrogenase reductase Sdr
CKY39_RS03660	COG1215	transferase activity, transferring glycosyl groups
CKY39_RS03665	COG0726	polysaccharide deacetylase
CKY39_RS03665	COG1649	PFAM Uncharacterised BCR, COG1649
CKY39_RS03680	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CKY39_RS03685	COG1280	lysine exporter protein (LysE YggA)
CKY39_RS03695	COG0384	phenazine biosynthesis protein PhzF
CKY39_RS03700	COG0625	glutathione transferase activity
CKY39_RS03720	COG0697	spore germination
CKY39_RS03750	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CKY39_RS03785	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CKY39_RS03790	COG1216	Glycosyl transferase, family 2
CKY39_RS03835	COG0463	Glycosyl transferase, family 2
CKY39_RS03865	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CKY39_RS03885	COG3959	Transketolase, thiamine diphosphate binding domain
CKY39_RS03890	COG3958	Transketolase
CKY39_RS03900	COG0463	Glycosyl transferase, family 2
CKY39_RS03915	COG0463	Glycosyl transferase, family 2
CKY39_RS03935	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CKY39_RS03940	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CKY39_RS03945	COG1309	transcriptional regulator
CKY39_RS03955	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CKY39_RS03960	COG2721	sulfolactate sulfo-lyase activity
CKY39_RS03965	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CKY39_RS03975	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CKY39_RS03980	COG2186	Transcriptional regulator
CKY39_RS03985	COG1028	Short-chain dehydrogenase reductase Sdr
CKY39_RS03990	COG1028	Short-chain dehydrogenase reductase Sdr
CKY39_RS04000	COG0583	DNA-binding transcription factor activity
CKY39_RS04005	COG4221	oxidoreductase activity
CKY39_RS04015	COG1960	acyl-CoA dehydrogenase activity
CKY39_RS04025	COG1024	Enoyl-CoA hydratase
CKY39_RS04025	COG1250	3-hydroxyacyl-CoA dehydrogenase
CKY39_RS04030	COG0183	Belongs to the thiolase family
CKY39_RS04060	COG0683	leucine binding
CKY39_RS04070	COG5265	(ABC) transporter
CKY39_RS04075	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CKY39_RS04085	COG3712	iron ion homeostasis
CKY39_RS04090	COG1595	DNA-templated transcription, initiation
CKY39_RS04095	COG0154	amidase activity
CKY39_RS04100	COG0583	DNA-binding transcription factor activity
CKY39_RS04105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CKY39_RS04115	COG0765	amino acid transport
CKY39_RS04120	COG1126	abc transporter atp-binding protein
CKY39_RS04125	COG1957	nucleoside hydrolase
CKY39_RS04130	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CKY39_RS04140	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CKY39_RS04145	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CKY39_RS04150	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CKY39_RS04200	COG0318	PFAM AMP-dependent synthetase and ligase
CKY39_RS04210	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CKY39_RS04215	COG1024	Enoyl-CoA hydratase
CKY39_RS04220	COG1960	acyl-CoA dehydrogenase activity
CKY39_RS04225	COG1960	acyl-CoA dehydrogenase activity
CKY39_RS04230	COG0183	Belongs to the thiolase family
CKY39_RS04235	COG1024	Enoyl-CoA hydratase
CKY39_RS04235	COG1250	3-hydroxyacyl-CoA dehydrogenase
CKY39_RS04240	COG0583	DNA-binding transcription factor activity
CKY39_RS04265	COG1595	DNA-templated transcription, initiation
CKY39_RS04270	COG0418	dihydroorotase activity
CKY39_RS04285	COG0501	Belongs to the peptidase M48B family
CKY39_RS04300	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
CKY39_RS04315	COG3604	Transcriptional regulator
CKY39_RS04325	COG1846	Transcriptional regulator
CKY39_RS04340	COG1566	PFAM secretion protein HlyD family protein
CKY39_RS04355	COG1187	pseudouridine synthase activity
CKY39_RS04360	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CKY39_RS04365	COG3181	Tripartite tricarboxylate transporter family receptor
CKY39_RS04390	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CKY39_RS04400	COG2807	transmembrane transport
CKY39_RS04405	COG0590	tRNA wobble adenosine to inosine editing
CKY39_RS04435	COG0656	L-ascorbic acid biosynthetic process
CKY39_RS04440	COG2814	Major facilitator Superfamily
CKY39_RS04455	COG0662	Cupin 2, conserved barrel domain protein
CKY39_RS04455	COG2207	Transcriptional regulator
CKY39_RS04475	COG0583	DNA-binding transcription factor activity
CKY39_RS04480	COG1335	isochorismatase
CKY39_RS04490	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CKY39_RS04510	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CKY39_RS04525	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CKY39_RS04535	COG0523	cobalamin synthesis protein
CKY39_RS04555	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CKY39_RS04560	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CKY39_RS04565	COG2001	Belongs to the MraZ family
CKY39_RS04570	COG0275	rRNA processing
CKY39_RS04575	COG3116	cell division
CKY39_RS04585	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CKY39_RS04590	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CKY39_RS04595	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CKY39_RS04600	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CKY39_RS04605	COG0772	Belongs to the SEDS family
CKY39_RS04610	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CKY39_RS04615	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CKY39_RS04620	COG1181	Belongs to the D-alanine--D-alanine ligase family
CKY39_RS04625	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CKY39_RS04640	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CKY39_RS04645	COG0583	DNA-binding transcription factor activity
CKY39_RS04650	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CKY39_RS04655	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CKY39_RS04665	COG0575	Belongs to the CDS family
CKY39_RS04680	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CKY39_RS04685	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CKY39_RS04700	COG3150	esterase
CKY39_RS04705	COG2197	response regulator
CKY39_RS04715	COG0772	Belongs to the SEDS family
CKY39_RS04720	COG0312	modulator of DNA gyrase
CKY39_RS04740	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CKY39_RS04755	COG0511	ligase activity, forming carbon-carbon bonds
CKY39_RS04765	COG2264	protein methyltransferase activity
CKY39_RS04775	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CKY39_RS04785	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CKY39_RS04815	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CKY39_RS04820	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CKY39_RS04840	COG2204	response regulator
CKY39_RS04850	COG2205	protein histidine kinase activity
CKY39_RS04855	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CKY39_RS04865	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CKY39_RS04870	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CKY39_RS04890	COG0037	tRNA processing
CKY39_RS04900	COG1028	Short-chain dehydrogenase reductase Sdr
CKY39_RS04915	COG2175	clavaminate synthase activity
CKY39_RS04925	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CKY39_RS04930	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CKY39_RS04950	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CKY39_RS04960	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CKY39_RS04970	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CKY39_RS04985	COG0583	DNA-binding transcription factor activity
CKY39_RS04990	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CKY39_RS04995	COG0739	heme binding
CKY39_RS04995	COG0741	lytic transglycosylase activity
CKY39_RS04995	COG1196	nuclear chromosome segregation
CKY39_RS05000	COG1285	pathogenesis
CKY39_RS05015	COG0617	tRNA 3'-terminal CCA addition
CKY39_RS05025	COG3387	PFAM Glycoside hydrolase 15-related
CKY39_RS05030	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CKY39_RS05065	COG2205	protein histidine kinase activity
CKY39_RS05085	COG2832	Protein of unknown function (DUF454)
CKY39_RS05095	COG5295	Hep Hag repeat protein
CKY39_RS05105	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CKY39_RS05105	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CKY39_RS05105	COG0506	proline dehydrogenase activity
CKY39_RS05125	COG0697	spore germination
CKY39_RS05155	COG0583	DNA-binding transcription factor activity
CKY39_RS05160	COG3386	PFAM SMP-30 Gluconolaconase
CKY39_RS05180	COG1879	ABC-type sugar transport system periplasmic component
CKY39_RS05185	COG4213	ABC transporter substrate-binding protein
CKY39_RS05195	COG4214	carbohydrate transport
CKY39_RS05200	COG1129	ABC transporter
CKY39_RS05205	COG1172	Belongs to the binding-protein-dependent transport system permease family
CKY39_RS05210	COG1172	Belongs to the binding-protein-dependent transport system permease family
CKY39_RS05240	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CKY39_RS05240	COG0189	ligase activity
CKY39_RS05245	COG0189	ligase activity
CKY39_RS05245	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CKY39_RS05250	COG1132	(ABC) transporter
CKY39_RS05260	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CKY39_RS05265	COG4178	(ABC) transporter
CKY39_RS05275	COG1840	ABC-type Fe3 transport system, periplasmic component
CKY39_RS05280	COG3842	ATPase activity
CKY39_RS05290	COG1053	succinate dehydrogenase
CKY39_RS05295	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CKY39_RS05305	COG2271	Major facilitator Superfamily
CKY39_RS05325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CKY39_RS05335	COG2863	cytochrome
CKY39_RS05350	COG2233	PERMEase
CKY39_RS05355	COG0583	DNA-binding transcription factor activity
CKY39_RS05445	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CKY39_RS05460	COG1765	OsmC-like protein
CKY39_RS05465	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
CKY39_RS05480	COG1473	amidohydrolase
CKY39_RS05490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CKY39_RS05495	COG0444	Belongs to the ABC transporter superfamily
CKY39_RS05500	COG4608	Belongs to the ABC transporter superfamily
CKY39_RS05505	COG0463	Glycosyl transferase, family 2
CKY39_RS05510	COG3384	dioxygenase
CKY39_RS05515	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CKY39_RS05520	COG1840	ABC-type Fe3 transport system, periplasmic component
CKY39_RS05545	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CKY39_RS05550	COG0166	Belongs to the GPI family
CKY39_RS05580	COG1175	transmembrane transport
CKY39_RS05585	COG0395	ABC-type sugar transport system, permease component
CKY39_RS05590	COG3842	ATPase activity
CKY39_RS05595	COG0246	Mannitol dehydrogenase
CKY39_RS05605	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CKY39_RS05615	COG4753	response regulator
CKY39_RS05615	COG2207	Transcriptional regulator
CKY39_RS05620	COG1070	Carbohydrate kinase
CKY39_RS05625	COG0459	protein refolding
CKY39_RS05630	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CKY39_RS05645	COG0583	DNA-binding transcription factor activity
CKY39_RS05655	COG0626	cystathionine gamma-synthase activity
CKY39_RS05670	COG0765	amino acid transport
CKY39_RS05680	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CKY39_RS05685	COG4774	siderophore transport
CKY39_RS05700	COG4772	TonB-dependent receptor
CKY39_RS05705	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CKY39_RS05715	COG1560	Kdo2-lipid A biosynthetic process
CKY39_RS05725	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CKY39_RS05735	COG1333	cytochrome c biogenesis protein
CKY39_RS05740	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CKY39_RS05745	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CKY39_RS05750	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CKY39_RS05755	COG0019	diaminopimelate decarboxylase activity
CKY39_RS05765	COG1965	Belongs to the frataxin family
CKY39_RS05800	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CKY39_RS05805	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CKY39_RS05810	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CKY39_RS05835	COG0069	glutamate synthase activity
CKY39_RS05835	COG0067	glutamate synthase
CKY39_RS05835	COG0070	glutamate synthase
CKY39_RS05845	COG1127	ABC transporter
CKY39_RS05850	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CKY39_RS05855	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CKY39_RS05860	COG2853	Lipoprotein
CKY39_RS05880	COG1131	(ABC) transporter
CKY39_RS05885	COG0842	Transport permease protein
CKY39_RS05890	COG5007	Belongs to the BolA IbaG family
CKY39_RS05895	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CKY39_RS05900	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CKY39_RS05920	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CKY39_RS05925	COG0131	Imidazoleglycerol-phosphate dehydratase
CKY39_RS05935	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CKY39_RS05950	COG1301	dicarboxylic acid transport
CKY39_RS05960	COG0107	imidazoleglycerol-phosphate synthase activity
CKY39_RS05965	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CKY39_RS05970	COG0140	phosphoribosyl-ATP diphosphatase activity
CKY39_RS05980	COG0537	adenosine 5'-monophosphoramidase activity
CKY39_RS05985	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CKY39_RS05990	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CKY39_RS05995	COG0805	protein transport
CKY39_RS06020	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CKY39_RS06025	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CKY39_RS06030	COG1970	mechanosensitive ion channel activity
CKY39_RS06035	COG1596	polysaccharide export
CKY39_RS06040	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CKY39_RS06075	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CKY39_RS06085	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CKY39_RS06095	COG3206	protein involved in exopolysaccharide biosynthesis
CKY39_RS06095	COG0489	protein tyrosine kinase activity
CKY39_RS06100	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CKY39_RS06110	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CKY39_RS06130	COG0723	plastoquinol--plastocyanin reductase activity
CKY39_RS06135	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CKY39_RS06140	COG2857	Cytochrome c1
CKY39_RS06145	COG0625	glutathione transferase activity
CKY39_RS06150	COG2969	positive regulation of protein catabolic process
CKY39_RS06165	COG1850	ribulose-bisphosphate carboxylase activity
CKY39_RS06175	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CKY39_RS06180	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CKY39_RS06185	COG1609	Transcriptional regulator
CKY39_RS06275	COG1595	DNA-templated transcription, initiation
CKY39_RS06295	COG2226	methyltransferase
CKY39_RS06310	COG2824	Alkylphosphonate utilization operon protein PhnA
CKY39_RS06320	COG0640	Transcriptional regulator
CKY39_RS06335	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CKY39_RS06345	COG0798	PFAM Bile acid sodium symporter
CKY39_RS06365	COG1595	DNA-templated transcription, initiation
CKY39_RS06375	COG3220	belongs to the UPF0276 family
CKY39_RS06395	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CKY39_RS06405	COG4591	ABC-type transport system involved in lipoprotein release permease component
CKY39_RS06410	COG1136	(ABC) transporter
CKY39_RS06445	COG0740	serine-type endopeptidase activity
CKY39_RS06465	COG0601	transmembrane transport
CKY39_RS06495	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CKY39_RS06500	COG0583	DNA-binding transcription factor activity
CKY39_RS06505	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CKY39_RS06560	COG1012	belongs to the aldehyde dehydrogenase family
CKY39_RS06595	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CKY39_RS06615	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CKY39_RS06630	COG1028	Short-chain dehydrogenase reductase Sdr
CKY39_RS06635	COG1012	belongs to the aldehyde dehydrogenase family
CKY39_RS06635	COG2030	dehydratase
CKY39_RS06660	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CKY39_RS06665	COG2151	metal-sulfur cluster biosynthetic enzyme
CKY39_RS06670	COG3396	Phenylacetate-CoA oxygenase
CKY39_RS06675	COG3460	Phenylacetate-CoA oxygenase
CKY39_RS06680	COG3396	Phenylacetate-CoA oxygenase
CKY39_RS06690	COG2050	protein possibly involved in aromatic compounds catabolism
CKY39_RS06695	COG1024	Enoyl-CoA hydratase
CKY39_RS06705	COG1309	transcriptional regulator
CKY39_RS06710	COG2304	oxidoreductase activity
CKY39_RS06720	COG0714	Associated with various cellular activities
CKY39_RS06725	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CKY39_RS06730	COG0084	hydrolase, TatD family'
CKY39_RS06745	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CKY39_RS06750	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CKY39_RS06790	COG1028	Short-chain dehydrogenase reductase Sdr
CKY39_RS06810	COG0583	DNA-binding transcription factor activity
CKY39_RS06830	COG0583	DNA-binding transcription factor activity
CKY39_RS06840	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CKY39_RS06845	COG0830	nickel cation binding
CKY39_RS06850	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CKY39_RS06875	COG0804	urea catabolic process
CKY39_RS06880	COG0832	Belongs to the urease beta subunit family
CKY39_RS06890	COG0831	urea catabolic process
CKY39_RS06910	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CKY39_RS06920	COG0653	protein targeting
CKY39_RS06925	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CKY39_RS06935	COG0494	nUDIX hydrolase
CKY39_RS06940	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CKY39_RS06940	COG2755	lipolytic protein G-D-S-L family
CKY39_RS06945	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CKY39_RS06950	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
CKY39_RS06960	COG1696	Membrane protein involved in D-alanine export
CKY39_RS06970	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CKY39_RS06990	COG0142	geranyltranstransferase activity
CKY39_RS06995	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CKY39_RS07000	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CKY39_RS07005	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CKY39_RS07010	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CKY39_RS07020	COG0494	nUDIX hydrolase
CKY39_RS07025	COG0442	prolyl-tRNA aminoacylation
CKY39_RS07030	COG0741	lytic transglycosylase activity
CKY39_RS07035	COG1253	flavin adenine dinucleotide binding
CKY39_RS07040	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CKY39_RS07045	COG2890	protein-(glutamine-N5) methyltransferase activity
CKY39_RS07050	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CKY39_RS07055	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CKY39_RS07070	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CKY39_RS07075	COG4120	Belongs to the binding-protein-dependent transport system permease family
CKY39_RS07085	COG1522	sequence-specific DNA binding
CKY39_RS07090	COG3264	Mechanosensitive ion channel
CKY39_RS07090	COG1511	domain protein
CKY39_RS07095	COG0584	glycerophosphoryl diester phosphodiesterase
CKY39_RS07100	COG3842	ATPase activity
CKY39_RS07105	COG0395	ABC-type sugar transport system, permease component
CKY39_RS07110	COG1175	transmembrane transport
CKY39_RS07120	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CKY39_RS07165	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CKY39_RS07185	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CKY39_RS07190	COG0494	nUDIX hydrolase
CKY39_RS07220	COG2823	Periplasmic or secreted lipoprotein
CKY39_RS07240	COG5487	UPF0391 membrane protein
CKY39_RS07245	COG4585	Histidine kinase
CKY39_RS07250	COG2197	response regulator
CKY39_RS07265	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CKY39_RS07270	COG0793	Belongs to the peptidase S41A family
CKY39_RS07275	COG0588	phosphoglycerate mutase activity
CKY39_RS07280	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CKY39_RS07290	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CKY39_RS07295	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CKY39_RS07305	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CKY39_RS07310	COG0720	synthase
CKY39_RS07315	COG0602	queuosine metabolic process
CKY39_RS07320	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CKY39_RS07325	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CKY39_RS07330	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CKY39_RS07350	COG0659	secondary active sulfate transmembrane transporter activity
CKY39_RS07355	COG1024	Enoyl-CoA hydratase
CKY39_RS07355	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CKY39_RS07385	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CKY39_RS07385	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CKY39_RS07390	COG0473	3-isopropylmalate dehydrogenase activity
CKY39_RS07400	COG3132	Protein of unknown function, DUF480
CKY39_RS07410	COG1522	sequence-specific DNA binding
CKY39_RS07415	COG1473	amidohydrolase
CKY39_RS07430	COG0489	protein tyrosine kinase activity
CKY39_RS07435	COG0583	DNA-binding transcription factor activity
CKY39_RS07450	COG0778	Nitroreductase
CKY39_RS07455	COG4149	molybdate abc transporter
CKY39_RS07460	COG0725	ABC transporter, periplasmic molybdate-binding protein
CKY39_RS07470	COG0243	molybdopterin cofactor binding
CKY39_RS07480	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CKY39_RS07485	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
CKY39_RS07495	COG3639	organic phosphonate transmembrane transporter activity
CKY39_RS07500	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CKY39_RS07505	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CKY39_RS07510	COG0709	Synthesizes selenophosphate from selenide and ATP
CKY39_RS07515	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CKY39_RS07525	COG0583	DNA-binding transcription factor activity
CKY39_RS07530	COG0477	Major facilitator Superfamily
CKY39_RS07535	COG0583	DNA-binding transcription factor activity
CKY39_RS07555	COG2900	Belongs to the SlyX family
CKY39_RS07560	COG1272	protein, Hemolysin III
CKY39_RS07565	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
CKY39_RS07580	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CKY39_RS07585	COG1845	cytochrome c oxidase, subunit III
CKY39_RS07590	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CKY39_RS07595	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CKY39_RS07600	COG0477	Major facilitator Superfamily
CKY39_RS07605	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CKY39_RS07620	COG0765	amino acid transport
CKY39_RS07625	COG0765	amino acid transport
CKY39_RS07635	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CKY39_RS07685	COG5295	Hep Hag repeat protein
CKY39_RS07695	COG0745	RESPONSE REGULATOR receiver
CKY39_RS07705	COG2205	protein histidine kinase activity
CKY39_RS07745	COG0737	Belongs to the 5'-nucleotidase family
CKY39_RS07750	COG1193	negative regulation of DNA recombination
CKY39_RS07755	COG2003	Belongs to the UPF0758 family
CKY39_RS07760	COG1047	Peptidyl-prolyl cis-trans
CKY39_RS07765	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CKY39_RS07775	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CKY39_RS07830	COG0484	heat shock protein binding
CKY39_RS07900	COG4735	regulation of single-species biofilm formation
CKY39_RS07960	COG3107	peptidoglycan biosynthetic process
CKY39_RS07995	COG2831	hemolysin activation secretion protein
CKY39_RS08095	COG1558	bacterial-type flagellum-dependent cell motility
CKY39_RS08120	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CKY39_RS08125	COG1706	bacterial-type flagellum-dependent cell motility
CKY39_RS08130	COG1705	Flagellar rod assembly protein muramidase FlgJ
CKY39_RS08130	COG3951	Flagellar rod assembly protein muramidase FlgJ
CKY39_RS08150	COG0840	transmembrane signaling receptor activity
CKY39_RS08155	COG0835	chemotaxis
CKY39_RS08165	COG1256	bacterial-type flagellum assembly
CKY39_RS08185	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CKY39_RS08190	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CKY39_RS08205	COG1942	4-Oxalocrotonate Tautomerase
CKY39_RS08210	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CKY39_RS08215	COG3275	phosphorelay sensor kinase activity
CKY39_RS08235	COG1987	bacterial-type flagellum assembly
CKY39_RS08260	COG1580	Controls the rotational direction of flagella during chemotaxis
CKY39_RS08280	COG1317	bacterial-type flagellum organization
CKY39_RS08290	COG1766	The M ring may be actively involved in energy transduction
CKY39_RS08295	COG1677	Flagellar hook-basal body complex protein FliE
CKY39_RS08305	COG1334	flagellar protein FlaG
CKY39_RS08310	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CKY39_RS08330	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CKY39_RS08355	COG2198	Histidine kinase
CKY39_RS08355	COG0643	Histidine kinase
CKY39_RS08360	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CKY39_RS08365	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CKY39_RS08370	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CKY39_RS08385	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CKY39_RS08395	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CKY39_RS08410	COG1191	sigma factor activity
CKY39_RS08450	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CKY39_RS08460	COG0583	DNA-binding transcription factor activity
CKY39_RS08465	COG1473	amidohydrolase
CKY39_RS08470	COG0583	DNA-binding transcription factor activity
CKY39_RS08480	COG1950	PFAM Membrane protein of
CKY39_RS08485	COG2198	Histidine kinase
CKY39_RS08485	COG2205	protein histidine kinase activity
CKY39_RS08485	COG0784	Response regulator, receiver
CKY39_RS08490	COG2197	response regulator
CKY39_RS08495	COG0180	Tryptophanyl-tRNA synthetase
CKY39_RS08500	COG1994	Peptidase M50
CKY39_RS08505	COG0009	L-threonylcarbamoyladenylate synthase
CKY39_RS08520	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CKY39_RS08525	COG3181	Tripartite tricarboxylate transporter family receptor
CKY39_RS08530	COG0583	DNA-binding transcription factor activity
CKY39_RS08550	COG0477	Major facilitator Superfamily
CKY39_RS08595	COG2814	Major facilitator Superfamily
CKY39_RS08605	COG3540	Alkaline phosphatase
CKY39_RS08610	COG0667	Aldo Keto reductase
CKY39_RS08670	COG0791	NLP P60 protein
CKY39_RS08690	COG4969	Belongs to the N-Me-Phe pilin family
CKY39_RS08720	COG1966	Carbon starvation protein
CKY39_RS08725	COG2879	small protein
CKY39_RS08735	COG2855	membrane
CKY39_RS08750	COG0829	nickel cation binding
CKY39_RS08760	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CKY39_RS08790	COG1301	dicarboxylic acid transport
CKY39_RS08835	COG0583	DNA-binding transcription factor activity
CKY39_RS08885	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CKY39_RS08895	COG2205	protein histidine kinase activity
CKY39_RS08940	COG0284	orotidine-5'-phosphate decarboxylase activity
CKY39_RS08955	COG0154	amidase activity
CKY39_RS08965	COG4608	Belongs to the ABC transporter superfamily
CKY39_RS08970	COG0444	Belongs to the ABC transporter superfamily
CKY39_RS08975	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CKY39_RS08985	COG0473	3-isopropylmalate dehydrogenase activity
CKY39_RS08990	COG0656	L-ascorbic acid biosynthetic process
CKY39_RS08995	COG2233	PERMEase
CKY39_RS09010	COG1953	Uracil, thiamine, allantoin
CKY39_RS09015	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CKY39_RS09030	COG2186	Transcriptional regulator
CKY39_RS09035	COG2351	hydroxyisourate hydrolase activity
CKY39_RS09070	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CKY39_RS09090	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CKY39_RS09100	COG3181	Tripartite tricarboxylate transporter family receptor
CKY39_RS09120	COG0730	response to heat
CKY39_RS09130	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CKY39_RS09140	COG2252	PERMEase
CKY39_RS09145	COG3845	ABC transporter
CKY39_RS09180	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CKY39_RS09185	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CKY39_RS09190	COG2814	Major facilitator Superfamily
CKY39_RS09195	COG0583	DNA-binding transcription factor activity
CKY39_RS09200	COG4977	sequence-specific DNA binding
CKY39_RS09205	COG2366	antibiotic biosynthetic process
CKY39_RS09220	COG4221	oxidoreductase activity
CKY39_RS09235	COG0402	S-adenosylhomocysteine deaminase activity
CKY39_RS09240	COG0717	Belongs to the dCTP deaminase family
CKY39_RS09245	COG2321	neutral zinc metallopeptidase
CKY39_RS09250	COG0513	Belongs to the DEAD box helicase family
CKY39_RS09265	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CKY39_RS09270	COG1960	acyl-CoA dehydrogenase activity
CKY39_RS09280	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CKY39_RS09290	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CKY39_RS09295	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CKY39_RS09300	COG1116	anion transmembrane transporter activity
CKY39_RS09320	COG2197	response regulator
CKY39_RS09330	COG0583	DNA-binding transcription factor activity
CKY39_RS09340	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CKY39_RS09345	COG1253	flavin adenine dinucleotide binding
CKY39_RS09360	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CKY39_RS09395	COG0583	DNA-binding transcription factor activity
CKY39_RS09425	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CKY39_RS09460	COG3181	Tripartite tricarboxylate transporter family receptor
CKY39_RS09530	COG0516	GMP reductase activity
CKY39_RS09535	COG3047	cAMP biosynthetic process
CKY39_RS09540	COG0210	DNA helicase
CKY39_RS09550	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CKY39_RS09580	COG4774	siderophore transport
CKY39_RS09595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CKY39_RS09605	COG0412	Dienelactone hydrolase
CKY39_RS09625	COG4172	Belongs to the ABC transporter superfamily
CKY39_RS09630	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CKY39_RS09635	COG0601	transmembrane transport
CKY39_RS09640	COG4166	transmembrane transport
CKY39_RS09650	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CKY39_RS09655	COG4608	Belongs to the ABC transporter superfamily
CKY39_RS09660	COG0444	Belongs to the ABC transporter superfamily
CKY39_RS09665	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CKY39_RS09670	COG0601	transmembrane transport
CKY39_RS09675	COG0747	negative chemotaxis
CKY39_RS09760	COG3064	Membrane
CKY39_RS09800	COG1722	exodeoxyribonuclease VII activity
CKY39_RS09805	COG0142	geranyltranstransferase activity
CKY39_RS09810	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CKY39_RS09815	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CKY39_RS09835	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CKY39_RS09840	COG0477	Major facilitator Superfamily
CKY39_RS09855	COG3842	ATPase activity
CKY39_RS09860	COG1840	ABC-type Fe3 transport system, periplasmic component
CKY39_RS09875	COG1012	belongs to the aldehyde dehydrogenase family
CKY39_RS09885	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CKY39_RS09910	COG2188	Transcriptional regulator
CKY39_RS09920	COG0559	Belongs to the binding-protein-dependent transport system permease family
CKY39_RS09980	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CKY39_RS10020	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CKY39_RS10025	COG1309	transcriptional regulator
CKY39_RS10035	COG1320	monovalent cation:proton antiporter activity
CKY39_RS10040	COG2212	antiporter activity
CKY39_RS10050	COG0651	ATP synthesis coupled electron transport
CKY39_RS10055	COG1006	Multisubunit Na H antiporter MnhC subunit
CKY39_RS10060	COG2111	Na H antiporter
CKY39_RS10060	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CKY39_RS10065	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CKY39_RS10090	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CKY39_RS10115	COG0287	Prephenate dehydrogenase
CKY39_RS10120	COG0077	Prephenate dehydratase
CKY39_RS10120	COG1605	Chorismate mutase
CKY39_RS10125	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CKY39_RS10145	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CKY39_RS10160	COG0582	viral genome integration into host DNA
CKY39_RS10185	COG0583	DNA-binding transcription factor activity
CKY39_RS10195	COG0508	dehydrogenase complex catalyzes the overall conversion of
CKY39_RS10200	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CKY39_RS10205	COG0596	Alpha beta hydrolase
CKY39_RS10210	COG0281	malic enzyme
CKY39_RS10210	COG0280	phosphate acetyltransferase
CKY39_RS10215	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CKY39_RS10220	COG1301	dicarboxylic acid transport
CKY39_RS10225	COG1252	NADH dehydrogenase
CKY39_RS10230	COG3243	poly(R)-hydroxyalkanoic acid synthase
CKY39_RS10235	COG0183	Belongs to the thiolase family
CKY39_RS10240	COG1028	Short-chain dehydrogenase reductase Sdr
CKY39_RS10250	COG1271	oxidase subunit
CKY39_RS10255	COG1294	oxidase, subunit
CKY39_RS10280	COG0583	DNA-binding transcription factor activity
CKY39_RS10285	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CKY39_RS10290	COG0154	amidase activity
CKY39_RS10310	COG1984	allophanate hydrolase subunit 2
CKY39_RS10315	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CKY39_RS10320	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CKY39_RS10325	COG3181	Tripartite tricarboxylate transporter family receptor
CKY39_RS10330	COG0473	3-isopropylmalate dehydrogenase activity
CKY39_RS10330	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CKY39_RS10345	COG0436	Aminotransferase
CKY39_RS10350	COG0473	3-isopropylmalate dehydrogenase activity
CKY39_RS10350	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CKY39_RS10360	COG0583	DNA-binding transcription factor activity
CKY39_RS10365	COG0583	DNA-binding transcription factor activity
CKY39_RS10375	COG0028	Belongs to the TPP enzyme family
CKY39_RS10375	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
CKY39_RS10380	COG1012	belongs to the aldehyde dehydrogenase family
CKY39_RS10390	COG0277	FAD linked oxidase domain protein
CKY39_RS10395	COG1960	acyl-CoA dehydrogenase activity
CKY39_RS10405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CKY39_RS10425	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CKY39_RS10455	COG2197	response regulator
CKY39_RS10460	COG4585	Histidine kinase
CKY39_RS10550	COG1028	Short-chain dehydrogenase reductase Sdr
CKY39_RS10560	COG1028	Short-chain dehydrogenase reductase Sdr
CKY39_RS10565	COG1609	Transcriptional regulator
CKY39_RS10585	COG0071	Belongs to the small heat shock protein (HSP20) family
CKY39_RS10600	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CKY39_RS10610	COG0583	DNA-binding transcription factor activity
CKY39_RS10625	COG0534	Mate efflux family protein
CKY39_RS10650	COG4221	oxidoreductase activity
CKY39_RS10655	COG0583	DNA-binding transcription factor activity
CKY39_RS10660	COG0604	alcohol dehydrogenase
CKY39_RS10660	COG3321	synthase
CKY39_RS10665	COG2267	carboxylic ester hydrolase activity
CKY39_RS10670	COG0604	alcohol dehydrogenase
CKY39_RS10675	COG1028	Short-chain dehydrogenase reductase Sdr
CKY39_RS10680	COG1902	pentaerythritol trinitrate reductase activity
CKY39_RS10700	COG2814	Major facilitator Superfamily
CKY39_RS10710	COG0318	PFAM AMP-dependent synthetase and ligase
CKY39_RS10730	COG3119	arylsulfatase activity
CKY39_RS10735	COG0583	DNA-binding transcription factor activity
CKY39_RS10745	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CKY39_RS10765	COG0402	S-adenosylhomocysteine deaminase activity
CKY39_RS10770	COG2814	Major facilitator Superfamily
CKY39_RS10775	COG0583	DNA-binding transcription factor activity
CKY39_RS10795	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CKY39_RS10800	COG0154	amidase activity
CKY39_RS10835	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CKY39_RS10845	COG3181	Tripartite tricarboxylate transporter family receptor
CKY39_RS10870	COG1024	Enoyl-CoA hydratase
CKY39_RS10875	COG1028	Short-chain dehydrogenase reductase Sdr
CKY39_RS10885	COG2030	dehydratase
CKY39_RS10895	COG0318	PFAM AMP-dependent synthetase and ligase
CKY39_RS10905	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CKY39_RS10955	COG2197	response regulator
CKY39_RS10960	COG2197	response regulator
CKY39_RS10985	COG2267	carboxylic ester hydrolase activity
CKY39_RS11000	COG2271	Major facilitator Superfamily
CKY39_RS11020	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CKY39_RS11020	COG4797	methyltransferase
CKY39_RS11030	COG1187	pseudouridine synthase activity
CKY39_RS11055	COG1058	Belongs to the CinA family
CKY39_RS11055	COG1546	Belongs to the CinA family
CKY39_RS11060	COG0174	glutamine synthetase
CKY39_RS11070	COG3852	Histidine kinase
CKY39_RS11075	COG2204	response regulator
CKY39_RS11085	COG0708	Exodeoxyribonuclease III
CKY39_RS11100	COG0303	'Molybdopterin
CKY39_RS11125	COG0437	4 iron, 4 sulfur cluster binding
CKY39_RS11160	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CKY39_RS11165	COG0596	Alpha beta hydrolase
CKY39_RS11175	COG1764	response to oxidative stress
CKY39_RS11215	COG1012	belongs to the aldehyde dehydrogenase family
CKY39_RS11235	COG1137	ATPase activity
CKY39_RS11265	COG3485	protocatechuate 3,4-dioxygenase
CKY39_RS11310	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CKY39_RS11330	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CKY39_RS11335	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
CKY39_RS11345	COG0535	radical SAM domain protein
CKY39_RS11360	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CKY39_RS11365	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CKY39_RS11370	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CKY39_RS11375	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CKY39_RS11385	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CKY39_RS11395	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CKY39_RS11405	COG0789	Transcriptional regulator
CKY39_RS11410	COG0446	pyridine nucleotide-disulphide oxidoreductase
CKY39_RS11410	COG1902	pentaerythritol trinitrate reductase activity
CKY39_RS11425	COG0501	Belongs to the peptidase M48B family
CKY39_RS11430	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CKY39_RS11450	COG0277	FAD linked oxidase domain protein
CKY39_RS11460	COG1295	ribonuclease BN
CKY39_RS11470	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CKY39_RS11480	COG2267	carboxylic ester hydrolase activity
CKY39_RS11500	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CKY39_RS11505	COG0583	DNA-binding transcription factor activity
CKY39_RS11530	COG3181	Tripartite tricarboxylate transporter family receptor
CKY39_RS11535	COG4638	Rieske (2fe-2S)
CKY39_RS11590	COG3265	gluconokinase activity
CKY39_RS11595	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CKY39_RS11605	COG1028	Short-chain dehydrogenase reductase Sdr
CKY39_RS11645	COG0431	NADPH-dependent FMN reductase
CKY39_RS11655	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CKY39_RS11660	COG0640	Transcriptional regulator
CKY39_RS11675	COG3070	regulator of competence-specific genes
CKY39_RS11680	COG0346	lactoylglutathione lyase activity
CKY39_RS11690	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CKY39_RS11695	COG0596	Alpha beta hydrolase
CKY39_RS11705	COG0625	glutathione transferase activity
CKY39_RS11725	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CKY39_RS11730	COG2719	SpoVR family
CKY39_RS11735	COG2718	Belongs to the UPF0229 family
CKY39_RS11740	COG2766	serine protein kinase
CKY39_RS11745	COG0484	heat shock protein binding
CKY39_RS11750	COG0443	Heat shock 70 kDa protein
CKY39_RS11755	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CKY39_RS11770	COG0688	phosphatidylethanolamine metabolic process
CKY39_RS11795	COG2721	sulfolactate sulfo-lyase activity
CKY39_RS11810	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CKY39_RS11820	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CKY39_RS11825	COG2186	Transcriptional regulator
CKY39_RS11830	COG3181	Tripartite tricarboxylate transporter family receptor
CKY39_RS11835	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CKY39_RS11845	COG3181	Tripartite tricarboxylate transporter family receptor
CKY39_RS11860	COG1012	belongs to the aldehyde dehydrogenase family
CKY39_RS11880	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CKY39_RS11890	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CKY39_RS11900	COG1802	Transcriptional regulator
CKY39_RS11955	COG0583	DNA-binding transcription factor activity
CKY39_RS11960	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CKY39_RS11965	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CKY39_RS11975	COG0517	IMP dehydrogenase activity
CKY39_RS11975	COG1125	glycine betaine transport
CKY39_RS11980	COG2814	Major facilitator Superfamily
CKY39_RS11995	COG1959	2 iron, 2 sulfur cluster binding
CKY39_RS11995	COG1295	ribonuclease BN
CKY39_RS12010	COG0123	including yeast histone deacetylase and acetoin utilization protein
CKY39_RS12025	COG3237	CsbD-like
CKY39_RS12030	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CKY39_RS12040	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CKY39_RS12055	COG0477	Major facilitator Superfamily
CKY39_RS12065	COG1309	transcriptional regulator
CKY39_RS12070	COG1611	Belongs to the LOG family
CKY39_RS12075	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CKY39_RS12090	COG0405	Gamma-glutamyltransferase
CKY39_RS12095	COG0322	excinuclease ABC activity
CKY39_RS12100	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CKY39_RS12110	COG0583	DNA-binding transcription factor activity
CKY39_RS12120	COG0473	3-isopropylmalate dehydrogenase activity
CKY39_RS12195	COG0270	DNA (cytosine-5-)-methyltransferase activity
CKY39_RS12440	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CKY39_RS12475	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CKY39_RS12495	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CKY39_RS12500	COG0670	Belongs to the BI1 family
CKY39_RS12505	COG3193	protein, possibly involved in utilization of glycolate and propanediol
CKY39_RS12535	COG3128	pkhd-type hydroxylase
CKY39_RS12540	COG4774	siderophore transport
CKY39_RS12545	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CKY39_RS12550	COG1477	protein flavinylation
CKY39_RS12580	COG3634	alkyl hydroperoxide reductase activity
CKY39_RS12585	COG4771	TonB-dependent receptor
CKY39_RS12590	COG3720	iron ion transport
CKY39_RS12605	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CKY39_RS12610	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CKY39_RS12615	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CKY39_RS12630	COG0360	Binds together with S18 to 16S ribosomal RNA
CKY39_RS12635	COG2965	DNA replication, synthesis of RNA primer
CKY39_RS12640	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CKY39_RS12645	COG0359	binds to the 23S rRNA
CKY39_RS12650	COG0305	Participates in initiation and elongation during chromosome replication
CKY39_RS12680	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CKY39_RS12685	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CKY39_RS12695	COG0436	Aminotransferase
CKY39_RS12710	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CKY39_RS12715	COG1763	Mo-molybdopterin cofactor biosynthetic process
CKY39_RS12720	COG0303	'Molybdopterin
CKY39_RS12740	COG0314	molybdopterin synthase activity
CKY39_RS12750	COG3181	Tripartite tricarboxylate transporter family receptor
CKY39_RS12755	COG0542	response to heat
CKY39_RS12770	COG1022	Amp-dependent synthetase and ligase
CKY39_RS12800	COG1309	transcriptional regulator
CKY39_RS12805	COG1024	Enoyl-CoA hydratase
CKY39_RS12810	COG0183	Belongs to the thiolase family
CKY39_RS12840	COG0583	DNA-binding transcription factor activity
CKY39_RS12855	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CKY39_RS12860	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CKY39_RS12900	COG3181	Tripartite tricarboxylate transporter family receptor
CKY39_RS12905	COG4974	Belongs to the 'phage' integrase family
CKY39_RS12910	COG0583	DNA-binding transcription factor activity
CKY39_RS12915	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CKY39_RS12920	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CKY39_RS12940	COG3181	Tripartite tricarboxylate transporter family receptor
CKY39_RS12945	COG1309	transcriptional regulator
CKY39_RS12950	COG0183	Belongs to the thiolase family
CKY39_RS12965	COG2833	Protein of unknown function (DUF455)
CKY39_RS12975	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CKY39_RS12985	COG1028	Short-chain dehydrogenase reductase Sdr
CKY39_RS13010	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CKY39_RS13015	COG0148	phosphopyruvate hydratase activity
CKY39_RS13025	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CKY39_RS13030	COG0504	CTP synthase activity
CKY39_RS13035	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CKY39_RS13045	COG0756	dUTP diphosphatase activity
CKY39_RS13055	COG1047	Peptidyl-prolyl cis-trans
CKY39_RS13060	COG2850	peptidyl-arginine hydroxylation
CKY39_RS13075	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CKY39_RS13080	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CKY39_RS13085	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CKY39_RS13095	COG2814	Major facilitator Superfamily
CKY39_RS13100	COG2814	Major facilitator Superfamily
CKY39_RS13110	COG0583	DNA-binding transcription factor activity
CKY39_RS13120	COG0741	lytic transglycosylase activity
CKY39_RS13165	COG0765	amino acid transport
CKY39_RS13170	COG0765	amino acid transport
CKY39_RS13175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CKY39_RS13180	COG1126	abc transporter atp-binding protein
CKY39_RS13190	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CKY39_RS13200	COG1609	Transcriptional regulator
CKY39_RS13215	COG2197	response regulator
CKY39_RS13225	COG2957	Belongs to the agmatine deiminase family
CKY39_RS13230	COG0583	DNA-binding transcription factor activity
CKY39_RS13240	COG5002	protein histidine kinase activity
CKY39_RS13255	COG1024	Enoyl-CoA hydratase
CKY39_RS13270	COG1960	acyl-CoA dehydrogenase activity
CKY39_RS13290	COG2271	Major facilitator Superfamily
CKY39_RS13315	COG2197	response regulator
CKY39_RS13320	COG3851	Histidine kinase
CKY39_RS13360	COG2308	Evidence 4 Homologs of previously reported genes of
CKY39_RS13375	COG2194	sulfuric ester hydrolase activity
CKY39_RS13385	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CKY39_RS13405	COG3842	ATPase activity
CKY39_RS13415	COG0395	ABC-type sugar transport system, permease component
CKY39_RS13435	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CKY39_RS13450	COG1131	(ABC) transporter
CKY39_RS13480	COG2951	lytic endotransglycosylase activity
CKY39_RS13495	COG0714	Associated with various cellular activities
CKY39_RS13505	COG1196	nuclear chromosome segregation
CKY39_RS13505	COG3264	Mechanosensitive ion channel
CKY39_RS13520	COG1960	acyl-CoA dehydrogenase activity
CKY39_RS13535	COG4988	ABC transporter
CKY39_RS13540	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CKY39_RS13545	COG1271	oxidase subunit
CKY39_RS13550	COG1294	oxidase, subunit
CKY39_RS13580	COG0318	PFAM AMP-dependent synthetase and ligase
CKY39_RS13590	COG2030	dehydratase
CKY39_RS13600	COG1028	Short-chain dehydrogenase reductase Sdr
CKY39_RS13605	COG1024	Enoyl-CoA hydratase
CKY39_RS13635	COG3795	YCII-related domain
CKY39_RS13640	COG3795	YCII-related domain
CKY39_RS13665	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CKY39_RS13675	COG2985	domain, Protein
CKY39_RS13680	COG2985	domain, Protein
CKY39_RS13735	COG0583	DNA-binding transcription factor activity
CKY39_RS13740	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CKY39_RS13765	COG0024	Methionine aminopeptidase
CKY39_RS13785	COG0642	Histidine kinase
CKY39_RS13790	COG0745	RESPONSE REGULATOR receiver
CKY39_RS13815	COG3468	outer membrane autotransporter barrel domain protein
CKY39_RS13820	COG1414	Transcriptional regulator
CKY39_RS13825	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CKY39_RS13830	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CKY39_RS13850	COG3185	4-Hydroxyphenylpyruvate dioxygenase
CKY39_RS13850	COG1082	Xylose isomerase domain protein TIM barrel
CKY39_RS13855	COG0477	Major facilitator Superfamily
CKY39_RS13880	COG3148	PFAM DTW domain containing protein
CKY39_RS13905	COG1473	amidohydrolase
CKY39_RS13955	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CKY39_RS13975	COG1309	transcriptional regulator
CKY39_RS13995	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CKY39_RS13995	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CKY39_RS14000	COG0509	glycine decarboxylation via glycine cleavage system
CKY39_RS14005	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CKY39_RS14040	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CKY39_RS14045	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CKY39_RS14060	COG1028	Short-chain dehydrogenase reductase Sdr
CKY39_RS14070	COG0824	Thioesterase
CKY39_RS14075	COG0642	Histidine kinase
CKY39_RS14080	COG0745	RESPONSE REGULATOR receiver
CKY39_RS14090	COG0671	phosphoesterase, PA-phosphatase related
CKY39_RS14095	COG2194	sulfuric ester hydrolase activity
CKY39_RS14105	COG4302	ethanolamine ammonia-lyase activity
CKY39_RS14110	COG4303	Ethanolamine ammonia lyase large subunit
CKY39_RS14115	COG0531	amino acid
CKY39_RS14120	COG0545	Peptidyl-prolyl cis-trans isomerase
CKY39_RS14130	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
CKY39_RS14140	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CKY39_RS14170	COG3284	Transcriptional regulator
CKY39_RS14175	COG1012	belongs to the aldehyde dehydrogenase family
CKY39_RS14235	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CKY39_RS14240	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CKY39_RS14255	COG0456	acetyltransferase
CKY39_RS14275	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CKY39_RS14305	COG1024	Enoyl-CoA hydratase
CKY39_RS14320	COG0583	DNA-binding transcription factor activity
CKY39_RS14325	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CKY39_RS14340	COG2818	Glycosylase
CKY39_RS14345	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CKY39_RS14385	COG0625	glutathione transferase activity
CKY39_RS14390	COG1183	phosphatidylcholine synthase activity
CKY39_RS14395	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CKY39_RS14395	COG0519	Catalyzes the synthesis of GMP from XMP
CKY39_RS14400	COG0583	DNA-binding transcription factor activity
CKY39_RS14405	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CKY39_RS14410	COG3181	Tripartite tricarboxylate transporter family receptor
CKY39_RS14430	COG0640	Transcriptional regulator
CKY39_RS14445	COG0318	PFAM AMP-dependent synthetase and ligase
CKY39_RS14450	COG1960	acyl-CoA dehydrogenase activity
CKY39_RS14460	COG1272	protein, Hemolysin III
CKY39_RS14465	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CKY39_RS14475	COG1024	Enoyl-CoA hydratase
CKY39_RS14515	COG1132	(ABC) transporter
CKY39_RS14520	COG3384	dioxygenase
CKY39_RS14545	COG0587	DNA-directed DNA polymerase activity
CKY39_RS14575	COG0583	DNA-binding transcription factor activity
CKY39_RS14630	COG0517	IMP dehydrogenase activity
CKY39_RS14660	COG0583	DNA-binding transcription factor activity
CKY39_RS14685	COG0745	RESPONSE REGULATOR receiver
CKY39_RS14720	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CKY39_RS14730	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CKY39_RS14735	COG3181	Tripartite tricarboxylate transporter family receptor
CKY39_RS14755	COG1414	Transcriptional regulator
CKY39_RS14760	COG1028	Short-chain dehydrogenase reductase Sdr
CKY39_RS14765	COG0028	Belongs to the TPP enzyme family
CKY39_RS14770	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
CKY39_RS14775	COG1012	belongs to the aldehyde dehydrogenase family
CKY39_RS14815	COG2271	Major facilitator Superfamily
CKY39_RS14860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CKY39_RS14870	COG3437	response regulator, receiver
CKY39_RS14875	COG2205	protein histidine kinase activity
CKY39_RS14875	COG0784	Response regulator, receiver
CKY39_RS14875	COG2198	Histidine kinase
CKY39_RS14930	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CKY39_RS14935	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CKY39_RS14945	COG1737	Transcriptional regulator
CKY39_RS14950	COG0647	UMP catabolic process
CKY39_RS14960	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CKY39_RS15020	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CKY39_RS15040	COG0583	DNA-binding transcription factor activity
CKY39_RS15055	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CKY39_RS15060	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CKY39_RS15065	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CKY39_RS15065	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CKY39_RS15075	COG1741	Belongs to the pirin family
CKY39_RS15080	COG2259	Doxx family
CKY39_RS15090	COG1741	Belongs to the pirin family
CKY39_RS15095	COG1054	Belongs to the UPF0176 family
CKY39_RS15105	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
CKY39_RS15105	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
CKY39_RS15120	COG0848	biopolymer transport protein
CKY39_RS15130	COG0824	Thioesterase
CKY39_RS15135	COG0436	Aminotransferase
CKY39_RS15140	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CKY39_RS15145	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CKY39_RS15160	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CKY39_RS15160	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CKY39_RS15165	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CKY39_RS15170	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CKY39_RS15175	COG0741	lytic transglycosylase activity
CKY39_RS15200	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CKY39_RS15230	COG0825	malonyl-CoA metabolic process
CKY39_RS15235	COG0037	tRNA processing
CKY39_RS15240	COG0527	aspartate kinase activity
CKY39_RS15290	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CKY39_RS15325	COG4585	Histidine kinase
CKY39_RS15330	COG0583	DNA-binding transcription factor activity
CKY39_RS15360	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CKY39_RS15395	COG0745	RESPONSE REGULATOR receiver
CKY39_RS15430	COG3181	Tripartite tricarboxylate transporter family receptor
CKY39_RS15520	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CKY39_RS15525	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CKY39_RS15530	COG1011	Hydrolase
CKY39_RS15540	COG1280	lysine exporter protein (LysE YggA)
CKY39_RS15550	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CKY39_RS15555	COG1562	ergosterol biosynthetic process
CKY39_RS15565	COG3158	transport of potassium into the cell
CKY39_RS15570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CKY39_RS15585	COG0544	peptidyl-prolyl cis-trans isomerase activity
CKY39_RS15590	COG0740	serine-type endopeptidase activity
CKY39_RS15595	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CKY39_RS15645	COG2113	Glycine betaine
CKY39_RS15650	COG4176	ABC-type proline glycine betaine transport system permease component
CKY39_RS15665	COG2910	NAD(P)H-binding
CKY39_RS15670	COG0583	DNA-binding transcription factor activity
CKY39_RS15680	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CKY39_RS15690	COG4654	Cytochrome c, class I
CKY39_RS15705	COG0129	dihydroxy-acid dehydratase activity
CKY39_RS15710	COG0583	DNA-binding transcription factor activity
CKY39_RS15715	COG0583	DNA-binding transcription factor activity
CKY39_RS15730	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CKY39_RS15735	COG1802	Transcriptional regulator
CKY39_RS15765	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CKY39_RS15780	COG0730	response to heat
CKY39_RS15810	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CKY39_RS15815	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CKY39_RS15825	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
CKY39_RS15830	COG0778	Nitroreductase
CKY39_RS15850	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CKY39_RS15855	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CKY39_RS15865	COG1346	cytolysis
CKY39_RS15885	COG0657	acetylesterase activity
CKY39_RS15890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CKY39_RS15900	COG1538	Outer membrane efflux protein
CKY39_RS15910	COG1492	cobalamin metabolic process
CKY39_RS15915	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CKY39_RS15920	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CKY39_RS15935	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CKY39_RS15940	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CKY39_RS15960	COG0560	Phosphoserine phosphatase
CKY39_RS15965	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CKY39_RS15970	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CKY39_RS15970	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CKY39_RS15975	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CKY39_RS15975	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CKY39_RS16000	COG1028	Short-chain dehydrogenase reductase Sdr
CKY39_RS16045	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CKY39_RS16055	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CKY39_RS16070	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
CKY39_RS16175	COG4626	Terminase
CKY39_RS16175	COG1802	Transcriptional regulator
CKY39_RS16310	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CKY39_RS16315	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CKY39_RS16330	COG0557	exoribonuclease II activity
CKY39_RS16335	COG1028	Short-chain dehydrogenase reductase Sdr
CKY39_RS16360	COG0052	Belongs to the universal ribosomal protein uS2 family
CKY39_RS16365	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CKY39_RS16370	COG0528	UMP kinase activity
CKY39_RS16375	COG0233	cytoplasmic translational termination
CKY39_RS16380	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CKY39_RS16385	COG0575	Belongs to the CDS family
CKY39_RS16390	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CKY39_RS16400	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CKY39_RS16415	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CKY39_RS16420	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CKY39_RS16425	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CKY39_RS16430	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CKY39_RS16440	COG0505	Belongs to the CarA family
CKY39_RS16445	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CKY39_RS16455	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CKY39_RS16470	COG1534	Rna-binding protein
CKY39_RS16475	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CKY39_RS16480	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CKY39_RS16490	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CKY39_RS16510	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CKY39_RS16515	COG1024	Enoyl-CoA hydratase
CKY39_RS16520	COG1250	3-hydroxyacyl-CoA dehydrogenase
CKY39_RS16525	COG2814	Major facilitator Superfamily
CKY39_RS16530	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CKY39_RS16540	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CKY39_RS16545	COG0252	asparaginase activity
CKY39_RS16550	COG0563	adenylate kinase activity
CKY39_RS16555	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CKY39_RS16560	COG2835	tetraacyldisaccharide 4'-kinase activity
CKY39_RS16570	COG0848	biopolymer transport protein
CKY39_RS16575	COG0811	peptide transport
CKY39_RS16580	COG1570	exodeoxyribonuclease VII activity
CKY39_RS16585	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CKY39_RS16650	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CKY39_RS16655	COG0542	response to heat
CKY39_RS16665	COG2925	Exonuclease
CKY39_RS16690	COG4191	Histidine kinase
CKY39_RS16695	COG4566	intracellular signal transduction
CKY39_RS16710	COG2808	Putative FMN-binding domain
CKY39_RS16725	COG1619	proteins homologs of microcin C7 resistance protein MccF
CKY39_RS16755	COG2205	protein histidine kinase activity
CKY39_RS16755	COG0784	Response regulator, receiver
CKY39_RS16765	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CKY39_RS16770	COG3437	response regulator, receiver
CKY39_RS16770	COG2205	protein histidine kinase activity
CKY39_RS16770	COG3850	Histidine kinase
CKY39_RS16770	COG4999	Histidine kinase
CKY39_RS16800	COG0156	8-amino-7-oxononanoate synthase activity
CKY39_RS16805	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CKY39_RS16810	COG0667	Aldo Keto reductase
CKY39_RS16815	COG2207	Transcriptional regulator
CKY39_RS16820	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CKY39_RS16825	COG3360	Dodecin
CKY39_RS16830	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CKY39_RS16835	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CKY39_RS16840	COG1473	amidohydrolase
CKY39_RS16850	COG1126	abc transporter atp-binding protein
CKY39_RS16855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CKY39_RS16865	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CKY39_RS16885	COG0601	transmembrane transport
CKY39_RS16890	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CKY39_RS16925	COG0505	Belongs to the CarA family
CKY39_RS16940	COG2207	Transcriptional regulator
CKY39_RS16945	COG1473	amidohydrolase
CKY39_RS16960	COG2205	protein histidine kinase activity
CKY39_RS16960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CKY39_RS16970	COG3539	Fimbrial protein
CKY39_RS16975	COG3539	Fimbrial protein
CKY39_RS16980	COG3121	Chaperone
CKY39_RS16985	COG3188	usher protein
CKY39_RS17000	COG0583	DNA-binding transcription factor activity
CKY39_RS17020	COG2351	hydroxyisourate hydrolase activity
CKY39_RS17025	COG0590	tRNA wobble adenosine to inosine editing
CKY39_RS17040	COG0318	PFAM AMP-dependent synthetase and ligase
CKY39_RS17050	COG0251	oxidation-reduction process
CKY39_RS17055	COG0666	response to abiotic stimulus
CKY39_RS17060	COG0084	hydrolase, TatD family'
CKY39_RS17075	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CKY39_RS17165	COG2183	response to ionizing radiation
CKY39_RS17170	COG4585	Histidine kinase
CKY39_RS17175	COG2201	protein-glutamate methylesterase activity
CKY39_RS17215	COG0534	Mate efflux family protein
CKY39_RS17230	COG4774	siderophore transport
CKY39_RS17235	COG3712	iron ion homeostasis
CKY39_RS17240	COG1595	DNA-templated transcription, initiation
CKY39_RS17255	COG0477	Major facilitator Superfamily
CKY39_RS17265	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CKY39_RS17265	COG3008	intermembrane lipid transfer
CKY39_RS17270	COG2995	paraquat-inducible protein a
CKY39_RS17275	COG2995	paraquat-inducible protein a
CKY39_RS17280	COG2814	Major facilitator Superfamily
CKY39_RS17285	COG2814	Major facilitator Superfamily
CKY39_RS17300	COG0583	DNA-binding transcription factor activity
CKY39_RS17310	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CKY39_RS17345	COG0247	lactate metabolic process
CKY39_RS17345	COG0277	FAD linked oxidase domain protein
CKY39_RS17350	COG1802	Transcriptional regulator
CKY39_RS17370	COG0583	DNA-binding transcription factor activity
CKY39_RS17375	COG2814	Major facilitator Superfamily
CKY39_RS17400	COG0583	DNA-binding transcription factor activity
CKY39_RS17405	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CKY39_RS17420	COG1960	acyl-CoA dehydrogenase activity
CKY39_RS17425	COG2130	NADP-dependent
CKY39_RS17455	COG1960	acyl-CoA dehydrogenase activity
CKY39_RS17465	COG0183	Belongs to the thiolase family
CKY39_RS17475	COG1024	Enoyl-CoA hydratase
CKY39_RS17475	COG1250	3-hydroxyacyl-CoA dehydrogenase
CKY39_RS17485	COG0411	ABC transporter
CKY39_RS17495	COG0559	Belongs to the binding-protein-dependent transport system permease family
CKY39_RS17510	COG0318	PFAM AMP-dependent synthetase and ligase
CKY39_RS17520	COG2272	Belongs to the type-B carboxylesterase lipase family
CKY39_RS17530	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CKY39_RS17535	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CKY39_RS17540	COG2917	probably involved in intracellular septation
CKY39_RS17550	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CKY39_RS17575	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CKY39_RS17575	COG0047	phosphoribosylformylglycinamidine synthase activity
CKY39_RS17580	COG0024	Methionine aminopeptidase
CKY39_RS17585	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CKY39_RS17595	COG2197	response regulator
CKY39_RS17610	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CKY39_RS17615	COG0765	amino acid transport
CKY39_RS17620	COG4597	amino acid ABC transporter
CKY39_RS17625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CKY39_RS17635	COG0242	peptide deformylase activity
CKY39_RS17645	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CKY39_RS17655	COG1196	nuclear chromosome segregation
CKY39_RS17670	COG3550	peptidyl-serine autophosphorylation
CKY39_RS17730	COG0433	COG0433 Predicted ATPase
CKY39_RS17735	COG4944	Protein of unknown function (DUF1109)
CKY39_RS17740	COG1595	DNA-templated transcription, initiation
CKY39_RS17765	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CKY39_RS17780	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CKY39_RS17790	COG3845	ABC transporter
CKY39_RS17795	COG4603	Belongs to the binding-protein-dependent transport system permease family
CKY39_RS17800	COG1079	Belongs to the binding-protein-dependent transport system permease family
CKY39_RS17810	COG0402	S-adenosylhomocysteine deaminase activity
CKY39_RS17830	COG3181	Tripartite tricarboxylate transporter family receptor
CKY39_RS17880	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CKY39_RS17885	COG2207	Transcriptional regulator
CKY39_RS17885	COG1917	Cupin 2, conserved barrel domain protein
CKY39_RS17925	COG2914	Belongs to the UPF0125 (RnfH) family
CKY39_RS17930	COG2867	negative regulation of translational initiation
CKY39_RS17935	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CKY39_RS17970	COG1217	gtp-binding protein TYPA
CKY39_RS17975	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CKY39_RS17980	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CKY39_RS17985	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CKY39_RS17995	COG0779	Required for maturation of 30S ribosomal subunits
CKY39_RS18000	COG0477	Major facilitator Superfamily
CKY39_RS18005	COG4172	Belongs to the ABC transporter superfamily
CKY39_RS18010	COG4239	(ABC) transporter, permease
CKY39_RS18015	COG4174	ABC transporter (Permease)
CKY39_RS18020	COG4166	transmembrane transport
CKY39_RS18025	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CKY39_RS18030	COG1793	dna ligase
CKY39_RS18075	COG2271	Major facilitator Superfamily
CKY39_RS18080	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CKY39_RS18095	COG0154	amidase activity
CKY39_RS18120	COG0784	Response regulator, receiver
CKY39_RS18120	COG2205	protein histidine kinase activity
CKY39_RS18125	COG2197	response regulator
CKY39_RS18140	COG2205	protein histidine kinase activity
CKY39_RS18140	COG0784	Response regulator, receiver
CKY39_RS18175	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CKY39_RS18195	COG0583	DNA-binding transcription factor activity
CKY39_RS18200	COG0436	Aminotransferase
CKY39_RS18220	COG1643	Atp-dependent helicase
CKY39_RS18225	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CKY39_RS18230	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CKY39_RS18230	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CKY39_RS18235	COG1280	lysine exporter protein (LysE YggA)
CKY39_RS18250	COG2171	N-acyltransferase activity
CKY39_RS18260	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CKY39_RS18265	COG2890	protein-(glutamine-N5) methyltransferase activity
CKY39_RS18270	COG0488	(ABC) transporter
CKY39_RS18295	COG0252	asparaginase activity
CKY39_RS18300	COG0583	DNA-binding transcription factor activity
CKY39_RS18320	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CKY39_RS18335	COG0823	Involved in the tonB-independent uptake of proteins
CKY39_RS18340	COG1132	(ABC) transporter
CKY39_RS18345	COG1802	Transcriptional regulator
CKY39_RS18355	COG3246	L-lysine catabolic process to acetate
CKY39_RS18365	COG1530	ribonuclease E activity
CKY39_RS18370	COG0424	maF-like protein
CKY39_RS18375	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CKY39_RS18380	COG0799	negative regulation of ribosome biogenesis
CKY39_RS18385	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CKY39_RS18390	COG0408	coproporphyrinogen oxidase activity
CKY39_RS18395	COG0151	Belongs to the GarS family
CKY39_RS18400	COG0217	transcriptional regulatory protein
CKY39_RS18405	COG2226	methyltransferase
CKY39_RS18425	COG1538	Outer membrane efflux protein
CKY39_RS18435	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CKY39_RS18440	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CKY39_RS18445	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CKY39_RS18450	COG4208	sulfate ABC transporter
CKY39_RS18460	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CKY39_RS18470	COG0450	alkyl hydroperoxide reductase
CKY39_RS18480	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CKY39_RS18485	COG4977	sequence-specific DNA binding
CKY39_RS18505	COG0765	amino acid transport
CKY39_RS18510	COG0765	amino acid transport
CKY39_RS18515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CKY39_RS18530	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CKY39_RS18540	COG3550	peptidyl-serine autophosphorylation
CKY39_RS18560	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CKY39_RS18570	COG1045	serine acetyltransferase
CKY39_RS18595	COG1116	anion transmembrane transporter activity
CKY39_RS18600	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CKY39_RS18605	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CKY39_RS18610	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CKY39_RS18615	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CKY39_RS18620	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CKY39_RS18625	COG0431	NADPH-dependent FMN reductase
CKY39_RS18635	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
CKY39_RS18640	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CKY39_RS18640	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CKY39_RS18650	COG0584	glycerophosphoryl diester phosphodiesterase
CKY39_RS18660	COG5002	protein histidine kinase activity
CKY39_RS18665	COG0745	RESPONSE REGULATOR receiver
CKY39_RS18670	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
CKY39_RS18675	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CKY39_RS18685	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CKY39_RS18695	COG0427	acetyl-CoA hydrolase
CKY39_RS18700	COG0583	DNA-binding transcription factor activity
CKY39_RS18705	COG0251	oxidation-reduction process
CKY39_RS18720	COG0583	DNA-binding transcription factor activity
CKY39_RS18725	COG0667	Aldo Keto reductase
CKY39_RS18745	COG0789	Transcriptional regulator
CKY39_RS18765	COG1446	asparaginase
CKY39_RS18770	COG4172	Belongs to the ABC transporter superfamily
CKY39_RS18775	COG0747	negative chemotaxis
CKY39_RS18785	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CKY39_RS18800	COG5002	protein histidine kinase activity
CKY39_RS18835	COG2895	sulfate adenylyltransferase (ATP) activity
CKY39_RS18840	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CKY39_RS18845	COG0492	ferredoxin-NADP+ reductase activity
CKY39_RS18860	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CKY39_RS18880	COG0351	phosphomethylpyrimidine kinase
CKY39_RS18895	COG2022	thiamine diphosphate biosynthetic process
CKY39_RS18960	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CKY39_RS18965	COG3321	synthase
CKY39_RS18965	COG0604	alcohol dehydrogenase
CKY39_RS18975	COG2267	carboxylic ester hydrolase activity
CKY39_RS19010	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CKY39_RS19015	COG0642	Histidine kinase
CKY39_RS19025	COG1414	Transcriptional regulator
CKY39_RS19050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CKY39_RS19050	COG2207	Transcriptional regulator
CKY39_RS19060	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CKY39_RS19065	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CKY39_RS19070	COG1414	Transcriptional regulator
CKY39_RS19085	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CKY39_RS19090	COG1183	phosphatidylcholine synthase activity
CKY39_RS19095	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CKY39_RS19100	COG0440	acetolactate synthase activity
CKY39_RS19105	COG0028	Belongs to the TPP enzyme family
CKY39_RS19130	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CKY39_RS19245	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CKY39_RS19255	COG1012	belongs to the aldehyde dehydrogenase family
CKY39_RS19275	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CKY39_RS19290	COG0328	RNA-DNA hybrid ribonuclease activity
CKY39_RS19295	COG2226	methyltransferase
CKY39_RS19300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CKY39_RS19305	COG0741	lytic transglycosylase activity
CKY39_RS19305	COG1388	LysM domain
CKY39_RS19310	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CKY39_RS19310	COG0475	glutathione-regulated potassium exporter activity
CKY39_RS19315	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CKY39_RS19325	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CKY39_RS19335	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CKY39_RS19340	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CKY39_RS19345	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CKY39_RS19365	COG1074	ATP-dependent DNA helicase activity
CKY39_RS19380	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CKY39_RS19385	COG0673	inositol 2-dehydrogenase activity
CKY39_RS19390	COG0254	rRNA binding
CKY39_RS19400	COG0534	Mate efflux family protein
CKY39_RS19420	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CKY39_RS19425	COG0581	inorganic phosphate transmembrane transporter activity
CKY39_RS19430	COG0573	inorganic phosphate transmembrane transporter activity
CKY39_RS19435	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CKY39_RS19440	COG0248	Ppx GppA phosphatase
CKY39_RS19465	COG0492	ferredoxin-NADP+ reductase activity
CKY39_RS19475	COG0625	glutathione transferase activity
CKY39_RS19495	COG0582	viral genome integration into host DNA
CKY39_RS19510	COG3179	chitinase
CKY39_RS19555	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CKY39_RS19770	COG3561	AntA/AntB antirepressor
CKY39_RS19825	COG1024	Enoyl-CoA hydratase
CKY39_RS19845	COG1522	sequence-specific DNA binding
CKY39_RS19850	COG1028	Short-chain dehydrogenase reductase Sdr
CKY39_RS19890	COG1028	Short-chain dehydrogenase reductase Sdr
CKY39_RS19910	COG1295	ribonuclease BN
CKY39_RS19920	COG2059	Chromate
CKY39_RS19925	COG0667	Aldo Keto reductase
CKY39_RS19945	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CKY39_RS19960	COG4181	ATPase activity
CKY39_RS19980	COG0626	cystathionine gamma-synthase activity
CKY39_RS19985	COG0501	Belongs to the peptidase M48B family
CKY39_RS20005	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CKY39_RS20010	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CKY39_RS20020	COG0330	HflC and HflK could
CKY39_RS20030	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CKY39_RS20035	COG1923	regulation of RNA biosynthetic process
CKY39_RS20040	COG1160	GTP binding
CKY39_RS20045	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CKY39_RS20055	COG0124	histidyl-tRNA synthetase
CKY39_RS20060	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CKY39_RS20075	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CKY39_RS20080	COG0105	UTP biosynthetic process
CKY39_RS20085	COG1187	pseudouridine synthase activity
CKY39_RS20090	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CKY39_RS20095	COG0564	pseudouridine synthase activity
CKY39_RS20105	COG1199	ATP-dependent helicase activity
CKY39_RS20125	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CKY39_RS20130	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CKY39_RS20135	COG0508	dehydrogenase complex catalyzes the overall conversion of
CKY39_RS20140	COG0567	Dehydrogenase, E1 component
CKY39_RS20160	COG2368	4-hydroxyphenylacetate
CKY39_RS20170	COG2133	pyrroloquinoline quinone binding
CKY39_RS20175	COG0791	NLP P60 protein
CKY39_RS20180	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CKY39_RS20190	COG0508	dehydrogenase complex catalyzes the overall conversion of
CKY39_RS20195	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CKY39_RS20205	COG4566	intracellular signal transduction
CKY39_RS20210	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CKY39_RS20225	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CKY39_RS20230	COG0167	dihydroorotate dehydrogenase activity
CKY39_RS20245	COG0579	oxidoreductase
CKY39_RS20280	COG1596	polysaccharide export
CKY39_RS20285	COG0489	protein tyrosine kinase activity
CKY39_RS20285	COG3206	protein involved in exopolysaccharide biosynthesis
CKY39_RS20290	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CKY39_RS20295	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CKY39_RS20325	COG0297	glycogen (starch) synthase activity
CKY39_RS20330	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CKY39_RS20335	COG2197	response regulator
CKY39_RS20345	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CKY39_RS20360	COG0633	Ferredoxin
CKY39_RS20365	COG0443	Heat shock 70 kDa protein
CKY39_RS20380	COG0822	iron-sulfur transferase activity
CKY39_RS20385	COG1104	cysteine desulfurase activity
CKY39_RS20390	COG1959	2 iron, 2 sulfur cluster binding
CKY39_RS20395	COG0556	nucleotide-excision repair
CKY39_RS20410	COG2878	Part of a membrane complex involved in electron transport
CKY39_RS20425	COG1522	sequence-specific DNA binding
CKY39_RS20440	COG4770	biotin carboxylase activity
CKY39_RS20445	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CKY39_RS20450	COG1703	isobutyryl-CoA mutase activity
CKY39_RS20460	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CKY39_RS20460	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CKY39_RS20720	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CKY39_RS20730	COG1802	Transcriptional regulator
CKY39_RS20735	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CKY39_RS20745	COG4166	transmembrane transport
CKY39_RS20760	COG4172	Belongs to the ABC transporter superfamily
CKY39_RS20765	COG0657	acetylesterase activity
CKY39_RS20770	COG2808	Putative FMN-binding domain
CKY39_RS20785	COG0028	Belongs to the TPP enzyme family
CKY39_RS20810	COG3813	Protein conserved in bacteria
CKY39_RS20820	COG0346	lactoylglutathione lyase activity
CKY39_RS20840	COG1595	DNA-templated transcription, initiation
CKY39_RS20845	COG3712	iron ion homeostasis
CKY39_RS20890	COG1733	regulation of RNA biosynthetic process
CKY39_RS20905	COG0583	DNA-binding transcription factor activity
CKY39_RS20910	COG2249	NAD(P)H dehydrogenase (quinone) activity
CKY39_RS20930	COG2076	Multidrug Resistance protein
CKY39_RS20965	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CKY39_RS21020	COG4774	siderophore transport
CKY39_RS21035	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CKY39_RS21035	COG4651	solute:proton antiporter activity
CKY39_RS21040	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CKY39_RS21050	COG1301	dicarboxylic acid transport
CKY39_RS21055	COG1028	Short-chain dehydrogenase reductase Sdr
CKY39_RS21065	COG1058	Belongs to the CinA family
CKY39_RS21065	COG1546	Belongs to the CinA family
CKY39_RS21085	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CKY39_RS21090	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
CKY39_RS21100	COG0583	DNA-binding transcription factor activity
CKY39_RS21110	COG0183	Belongs to the thiolase family
CKY39_RS21115	COG3243	poly(R)-hydroxyalkanoic acid synthase
CKY39_RS21150	COG3045	CreA protein
CKY39_RS21160	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CKY39_RS21195	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CKY39_RS21235	COG1132	(ABC) transporter
CKY39_RS21245	COG1742	UPF0060 membrane protein
CKY39_RS21265	COG2885	chlorophyll binding
CKY39_RS21290	COG0387	Pfam Sodium calcium exchanger
CKY39_RS21300	COG2197	response regulator
CKY39_RS21350	COG4964	Belongs to the GSP D family
CKY39_RS21365	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CKY39_RS21370	COG3181	Tripartite tricarboxylate transporter family receptor
CKY39_RS21425	COG0006	proline dipeptidase activity
CKY39_RS21430	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CKY39_RS21450	COG1522	sequence-specific DNA binding
CKY39_RS21475	COG0275	rRNA processing
CKY39_RS21515	COG0811	peptide transport
CKY39_RS21565	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CKY39_RS21590	COG1473	amidohydrolase
CKY39_RS21625	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CKY39_RS21635	COG0417	DNA replication proofreading
CKY39_RS21670	COG0436	Aminotransferase
CKY39_RS21675	COG1126	abc transporter atp-binding protein
CKY39_RS21680	COG0765	amino acid transport
CKY39_RS21685	COG0765	amino acid transport
CKY39_RS21690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CKY39_RS21705	COG0768	penicillin binding
CKY39_RS21720	COG1309	transcriptional regulator
CKY39_RS21760	COG1309	transcriptional regulator
CKY39_RS21795	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CKY39_RS21820	COG1595	DNA-templated transcription, initiation
CKY39_RS21840	COG0583	DNA-binding transcription factor activity
CKY39_RS21845	COG2031	fatty acid transporter
CKY39_RS21855	COG2423	ornithine cyclodeaminase activity
CKY39_RS21860	COG0583	DNA-binding transcription factor activity
CKY39_RS21880	COG3473	Maleate cis-trans isomerase
CKY39_RS21890	COG0277	FAD linked oxidase domain protein
CKY39_RS21905	COG0179	Fumarylacetoacetate (FAA) hydrolase
CKY39_RS21920	COG3483	tryptophan 2,3-dioxygenase activity
CKY39_RS21930	COG1522	sequence-specific DNA binding
CKY39_RS21940	COG1396	sequence-specific DNA binding
CKY39_RS21945	COG3181	Tripartite tricarboxylate transporter family receptor
CKY39_RS21955	COG0235	Class ii aldolase
CKY39_RS21960	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CKY39_RS21980	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
CKY39_RS22000	COG0583	DNA-binding transcription factor activity
CKY39_RS22005	COG3384	dioxygenase
CKY39_RS22020	COG1802	Transcriptional regulator
CKY39_RS22035	COG3384	dioxygenase
CKY39_RS22050	COG4569	acetaldehyde dehydrogenase (acetylating) activity
CKY39_RS22055	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CKY39_RS22060	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CKY39_RS22090	COG0179	Fumarylacetoacetate (FAA) hydrolase
CKY39_RS22100	COG3181	Tripartite tricarboxylate transporter family receptor
CKY39_RS22120	COG0583	DNA-binding transcription factor activity
CKY39_RS22135	COG0154	amidase activity
CKY39_RS22140	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CKY39_RS22145	COG1024	Enoyl-CoA hydratase
CKY39_RS22185	COG0730	response to heat
CKY39_RS22190	COG0402	S-adenosylhomocysteine deaminase activity
CKY39_RS22195	COG1028	Short-chain dehydrogenase reductase Sdr
CKY39_RS22200	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CKY39_RS22220	COG1024	Enoyl-CoA hydratase
CKY39_RS22240	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CKY39_RS22245	COG0583	DNA-binding transcription factor activity
CKY39_RS22270	COG1028	Short-chain dehydrogenase reductase Sdr
CKY39_RS22275	COG3181	Tripartite tricarboxylate transporter family receptor
CKY39_RS22280	COG1473	amidohydrolase
CKY39_RS22295	COG0776	regulation of translation
CKY39_RS22300	COG0072	phenylalanine-tRNA ligase activity
CKY39_RS22300	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CKY39_RS22305	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CKY39_RS22310	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CKY39_RS22315	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CKY39_RS22320	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CKY39_RS22325	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CKY39_RS22365	COG2207	Transcriptional regulator
CKY39_RS22375	COG0028	Belongs to the TPP enzyme family
CKY39_RS22380	COG1309	transcriptional regulator
CKY39_RS22390	COG0673	inositol 2-dehydrogenase activity
CKY39_RS22410	COG3214	Protein conserved in bacteria
CKY39_RS22415	COG4774	siderophore transport
CKY39_RS22420	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CKY39_RS22435	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CKY39_RS22440	COG0802	atpase or kinase
CKY39_RS22445	COG0860	N-Acetylmuramoyl-L-alanine amidase
CKY39_RS22455	COG2226	methyltransferase
CKY39_RS22460	COG0789	Transcriptional regulator
CKY39_RS22470	COG0586	Pfam SNARE associated Golgi protein
CKY39_RS22480	COG0583	DNA-binding transcription factor activity
CKY39_RS22485	COG2271	Major facilitator Superfamily
CKY39_RS22490	COG0179	Fumarylacetoacetate (FAA) hydrolase
CKY39_RS22495	COG0129	dihydroxy-acid dehydratase activity
CKY39_RS22505	COG0477	Major facilitator Superfamily
CKY39_RS22535	COG2207	Transcriptional regulator
CKY39_RS22540	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CKY39_RS22545	COG1136	(ABC) transporter
CKY39_RS22555	COG2186	Transcriptional regulator
CKY39_RS22570	COG3795	YCII-related domain
CKY39_RS22575	COG4941	Belongs to the sigma-70 factor family
CKY39_RS22645	COG0559	Belongs to the binding-protein-dependent transport system permease family
CKY39_RS22675	COG1335	isochorismatase
CKY39_RS22705	COG1846	Transcriptional regulator
CKY39_RS22710	COG1132	(ABC) transporter
CKY39_RS22720	COG0494	nUDIX hydrolase
CKY39_RS22730	COG1007	ATP synthesis coupled electron transport
CKY39_RS22745	COG0713	ATP synthesis coupled electron transport
CKY39_RS22755	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CKY39_RS22760	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CKY39_RS22765	COG1034	ATP synthesis coupled electron transport
CKY39_RS22780	COG0649	NAD binding
CKY39_RS22785	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CKY39_RS22790	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CKY39_RS22795	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CKY39_RS22810	COG0149	triose-phosphate isomerase activity
CKY39_RS22820	COG1185	polyribonucleotide nucleotidyltransferase activity
CKY39_RS22825	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CKY39_RS22840	COG0436	Aminotransferase
CKY39_RS22845	COG0683	leucine binding
CKY39_RS22860	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CKY39_RS22865	COG3707	response regulator
CKY39_RS22870	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CKY39_RS22875	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CKY39_RS22880	COG1116	anion transmembrane transporter activity
CKY39_RS22890	COG2223	nitrite transmembrane transporter activity
CKY39_RS22895	COG0515	serine threonine protein kinase
CKY39_RS22895	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CKY39_RS22900	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CKY39_RS22915	COG0243	molybdopterin cofactor binding
CKY39_RS22920	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CKY39_RS22935	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CKY39_RS22940	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CKY39_RS22965	COG2081	HI0933 family
CKY39_RS22970	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CKY39_RS22980	COG0494	nUDIX hydrolase
CKY39_RS23000	COG0385	Bile acid
CKY39_RS23005	COG2072	flavoprotein involved in K transport
CKY39_RS23010	COG0300	oxidoreductase activity
CKY39_RS23015	COG1063	alcohol dehydrogenase
CKY39_RS23020	COG3842	ATPase activity
CKY39_RS23025	COG0395	ABC-type sugar transport system, permease component
CKY39_RS23030	COG1175	transmembrane transport
CKY39_RS23035	COG1653	transport
CKY39_RS23045	COG0312	modulator of DNA gyrase
CKY39_RS23055	COG0521	Mo-molybdopterin cofactor biosynthetic process
CKY39_RS23120	COG0475	glutathione-regulated potassium exporter activity
CKY39_RS23125	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CKY39_RS23135	COG0789	Transcriptional regulator
CKY39_RS23140	COG1960	acyl-CoA dehydrogenase activity
CKY39_RS23155	COG0604	alcohol dehydrogenase
CKY39_RS23160	COG1733	regulation of RNA biosynthetic process
CKY39_RS23165	COG1045	serine acetyltransferase
CKY39_RS23175	COG0483	inositol monophosphate 1-phosphatase activity
CKY39_RS23180	COG1289	transmembrane transporter activity
CKY39_RS23205	COG1522	sequence-specific DNA binding
CKY39_RS23225	COG2311	Membrane
CKY39_RS23235	COG0583	DNA-binding transcription factor activity
CKY39_RS23240	COG3181	Tripartite tricarboxylate transporter family receptor
CKY39_RS23260	COG3119	arylsulfatase activity
CKY39_RS23290	COG2274	protein secretion by the type I secretion system
CKY39_RS23310	COG2202	Pas domain
CKY39_RS23310	COG2205	protein histidine kinase activity
CKY39_RS23315	COG1695	Transcriptional regulator
CKY39_RS23320	COG2375	cellular response to nickel ion
CKY39_RS23325	COG0598	Magnesium transport protein CorA
CKY39_RS23340	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CKY39_RS23360	COG4941	Belongs to the sigma-70 factor family
CKY39_RS23365	COG3795	YCII-related domain
CKY39_RS23370	COG1028	Short-chain dehydrogenase reductase Sdr
CKY39_RS23380	COG4585	Histidine kinase
CKY39_RS23405	COG1968	undecaprenyl-diphosphatase activity
CKY39_RS23420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CKY39_RS23425	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CKY39_RS23430	COG1737	Transcriptional regulator
CKY39_RS23475	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CKY39_RS23500	COG2972	Histidine kinase
CKY39_RS23515	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CKY39_RS23550	COG0004	ammonium transporteR
CKY39_RS23575	COG4774	siderophore transport
CKY39_RS23590	COG1131	(ABC) transporter
CKY39_RS23595	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CKY39_RS23605	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CKY39_RS23635	COG1028	Short-chain dehydrogenase reductase Sdr
CKY39_RS23645	COG2918	glutathione biosynthetic process
CKY39_RS23655	COG0400	carboxylic ester hydrolase activity
CKY39_RS23670	COG0523	cobalamin synthesis protein
CKY39_RS23705	COG4774	siderophore transport
CKY39_RS23750	COG2354	Protein conserved in bacteria
CKY39_RS23760	COG4628	conserved protein (DUF2132)
CKY39_RS23775	COG0564	pseudouridine synthase activity
CKY39_RS23780	COG0589	response to stress
CKY39_RS23795	COG0583	DNA-binding transcription factor activity
CKY39_RS23805	COG0511	ligase activity, forming carbon-carbon bonds
CKY39_RS23820	COG1984	allophanate hydrolase subunit 2
CKY39_RS23825	COG1879	ABC-type sugar transport system periplasmic component
CKY39_RS23830	COG1129	ABC transporter
CKY39_RS23835	COG1172	Belongs to the binding-protein-dependent transport system permease family
CKY39_RS23840	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CKY39_RS23855	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
CKY39_RS23860	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CKY39_RS23865	COG1252	NADH dehydrogenase
CKY39_RS23880	COG1525	nuclease
CKY39_RS23885	COG1609	Transcriptional regulator
CKY39_RS23900	COG3246	L-lysine catabolic process to acetate
CKY39_RS23935	COG4773	Receptor
CKY39_RS23940	COG3712	iron ion homeostasis
CKY39_RS23945	COG1595	DNA-templated transcription, initiation
CKY39_RS23950	COG0300	oxidoreductase activity
CKY39_RS23960	COG0318	PFAM AMP-dependent synthetase and ligase
CKY39_RS23970	COG1764	response to oxidative stress
CKY39_RS23990	COG1028	Short-chain dehydrogenase reductase Sdr
CKY39_RS24000	COG2271	Major facilitator Superfamily
CKY39_RS24015	COG0765	amino acid transport
CKY39_RS24020	COG0765	amino acid transport
CKY39_RS24030	COG0583	DNA-binding transcription factor activity
CKY39_RS24035	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CKY39_RS24045	COG0454	-acetyltransferase
CKY39_RS24055	COG0584	glycerophosphoryl diester phosphodiesterase
CKY39_RS24075	COG2132	Multicopper oxidase
CKY39_RS24100	COG3191	aminopeptidase activity
CKY39_RS24115	COG0488	(ABC) transporter
CKY39_RS24120	COG0513	Belongs to the DEAD box helicase family
CKY39_RS24135	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CKY39_RS24140	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CKY39_RS24145	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CKY39_RS24150	COG2186	Transcriptional regulator
CKY39_RS24155	COG0129	dihydroxy-acid dehydratase activity
CKY39_RS24160	COG3734	2-keto-3-deoxy-galactonokinase
CKY39_RS24165	COG0800	Aldolase
CKY39_RS24170	COG0235	Class ii aldolase
CKY39_RS24180	COG1028	Short-chain dehydrogenase reductase Sdr
CKY39_RS24205	COG1840	ABC-type Fe3 transport system, periplasmic component
CKY39_RS24215	COG3842	ATPase activity
CKY39_RS24230	COG0346	lactoylglutathione lyase activity
CKY39_RS24245	COG0800	Aldolase
CKY39_RS24270	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CKY39_RS24275	COG0259	pyridoxamine-phosphate oxidase activity
CKY39_RS24305	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CKY39_RS24310	COG1309	transcriptional regulator
CKY39_RS24315	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CKY39_RS24340	COG2169	Transcriptional regulator
CKY39_RS24350	COG0697	spore germination
CKY39_RS24370	COG0318	PFAM AMP-dependent synthetase and ligase
CKY39_RS24395	COG0625	glutathione transferase activity
CKY39_RS24420	COG2366	antibiotic biosynthetic process
CKY39_RS24490	COG3251	PFAM MbtH domain protein
CKY39_RS24550	COG1028	Short-chain dehydrogenase reductase Sdr
CKY39_RS24575	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CKY39_RS24585	COG2205	protein histidine kinase activity
CKY39_RS24585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CKY39_RS24615	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CKY39_RS24640	COG0285	dihydrofolate synthase activity
CKY39_RS24645	COG1393	Belongs to the ArsC family
CKY39_RS24655	COG3123	guanosine phosphorylase activity
CKY39_RS24660	COG0137	argininosuccinate synthase activity
CKY39_RS24670	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CKY39_RS24675	COG1666	GTP binding
CKY39_RS24685	COG0251	oxidation-reduction process
CKY39_RS24690	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CKY39_RS24695	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CKY39_RS24700	COG0667	Aldo Keto reductase
CKY39_RS24715	COG1464	Belongs to the NlpA lipoprotein family
CKY39_RS24725	COG0583	DNA-binding transcription factor activity
CKY39_RS24730	COG3960	tartronate-semialdehyde synthase activity
CKY39_RS24735	COG3622	Belongs to the hyi family
CKY39_RS24740	COG2084	Dehydrogenase
CKY39_RS24750	COG0280	phosphate acetyltransferase
CKY39_RS24750	COG0281	malic enzyme
CKY39_RS24770	COG1414	Transcriptional regulator
CKY39_RS24775	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CKY39_RS24790	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CKY39_RS24800	COG1116	anion transmembrane transporter activity
CKY39_RS24805	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CKY39_RS24850	COG0642	Histidine kinase
CKY39_RS24870	COG1733	regulation of RNA biosynthetic process
CKY39_RS24890	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CKY39_RS24900	COG1464	Belongs to the NlpA lipoprotein family
CKY39_RS24905	COG2011	ABC-type metal ion transport system permease component
CKY39_RS24910	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CKY39_RS24915	COG1464	Belongs to the NlpA lipoprotein family
CKY39_RS24925	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CKY39_RS24930	COG0308	aminopeptidase N
CKY39_RS24935	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CKY39_RS24945	COG1403	HNH endonuclease
CKY39_RS25070	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CKY39_RS25080	COG0183	Belongs to the thiolase family
CKY39_RS25120	COG0604	alcohol dehydrogenase
CKY39_RS25125	COG0596	Alpha beta hydrolase
CKY39_RS25130	COG1250	3-hydroxyacyl-CoA dehydrogenase
CKY39_RS25145	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CKY39_RS25150	COG0501	Belongs to the peptidase M48B family
CKY39_RS25155	COG2154	pterin-4-alpha-carbinolamine dehydratase
CKY39_RS25160	COG1162	GTPase activity
CKY39_RS25170	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CKY39_RS25175	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CKY39_RS25180	COG0494	nUDIX hydrolase
CKY39_RS25185	COG0335	large ribosomal subunit rRNA binding
CKY39_RS25190	COG0336	Belongs to the RNA methyltransferase TrmD family
CKY39_RS25195	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CKY39_RS25200	COG0228	four-way junction DNA binding
CKY39_RS25265	COG2608	mercury ion transmembrane transporter activity
CKY39_RS25340	COG0306	phosphate transporter
CKY39_RS25345	COG1392	Phosphate transport regulator
CKY39_RS25350	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CKY39_RS25355	COG0617	tRNA 3'-terminal CCA addition
CKY39_RS25360	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CKY39_RS25365	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CKY39_RS25385	COG1917	Cupin 2, conserved barrel domain protein
CKY39_RS25385	COG4977	sequence-specific DNA binding
CKY39_RS25390	COG4941	Belongs to the sigma-70 factor family
CKY39_RS25400	COG3795	YCII-related domain
CKY39_RS25420	COG0728	peptidoglycan biosynthetic process
CKY39_RS25425	COG0268	Binds directly to 16S ribosomal RNA
CKY39_RS25435	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CKY39_RS25440	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CKY39_RS25450	COG0727	PFAM Uncharacterised protein family (UPF0153)
CKY39_RS25455	COG1522	sequence-specific DNA binding
CKY39_RS25460	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CKY39_RS25470	COG3483	tryptophan 2,3-dioxygenase activity
CKY39_RS25480	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CKY39_RS25490	COG1918	ferrous iron import across plasma membrane
CKY39_RS25490	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CKY39_RS25495	COG2822	iron ion transport
CKY39_RS25505	COG2822	iron ion transport
CKY39_RS25510	COG0672	)-iron permease
CKY39_RS25520	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CKY39_RS25585	COG4106	trans-aconitate 2-methyltransferase activity
CKY39_RS25590	COG0039	L-malate dehydrogenase activity
CKY39_RS25595	COG2188	Transcriptional regulator
CKY39_RS25610	COG1053	succinate dehydrogenase
CKY39_RS25615	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CKY39_RS25620	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CKY39_RS25625	COG0372	Belongs to the citrate synthase family
CKY39_RS25635	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CKY39_RS25640	COG0066	3-isopropylmalate dehydratase activity
CKY39_RS25645	COG0473	3-isopropylmalate dehydrogenase activity
CKY39_RS25650	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CKY39_RS25660	COG0101	tRNA pseudouridine synthase activity
CKY39_RS25665	COG0135	phosphoribosylanthranilate isomerase activity
CKY39_RS25670	COG0133	tryptophan synthase activity
CKY39_RS25680	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CKY39_RS25685	COG0762	integral membrane protein
CKY39_RS25690	COG1215	transferase activity, transferring glycosyl groups
CKY39_RS25705	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CKY39_RS25720	COG0443	Heat shock 70 kDa protein
CKY39_RS25725	COG1451	nucleotide metabolic process
CKY39_RS25735	COG1472	Belongs to the glycosyl hydrolase 3 family
CKY39_RS25740	COG0736	holo-[acyl-carrier-protein] synthase activity
CKY39_RS25745	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CKY39_RS25765	COG0571	ribonuclease III activity
CKY39_RS25775	COG0681	Belongs to the peptidase S26 family
CKY39_RS25780	COG0481	GTPase activity
CKY39_RS25785	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CKY39_RS25810	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CKY39_RS25815	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CKY39_RS25825	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CKY39_RS25830	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CKY39_RS25835	COG0416	fatty acid biosynthetic process
CKY39_RS25840	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CKY39_RS25845	COG1399	metal-binding, possibly nucleic acid-binding protein
CKY39_RS25850	COG0424	maF-like protein
CKY39_RS25855	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CKY39_RS25860	COG2223	nitrite transmembrane transporter activity
CKY39_RS25865	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CKY39_RS25865	COG0616	signal peptide processing
CKY39_RS25895	COG0477	Major facilitator Superfamily
CKY39_RS25910	COG1587	Uroporphyrinogen-III synthase
CKY39_RS25915	COG0181	hydroxymethylbilane synthase activity
CKY39_RS25920	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CKY39_RS25930	COG3459	Glycosyltransferase 36 associated
CKY39_RS25945	COG0583	DNA-binding transcription factor activity
CKY39_RS25960	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CKY39_RS25990	COG3275	phosphorelay sensor kinase activity
CKY39_RS25995	COG0165	Argininosuccinate lyase
CKY39_RS26005	COG0477	Major facilitator Superfamily
CKY39_RS26010	COG4566	intracellular signal transduction
CKY39_RS26095	COG1280	lysine exporter protein (LysE YggA)
CKY39_RS26115	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CKY39_RS26120	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CKY39_RS26125	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CKY39_RS26130	COG2186	Transcriptional regulator
CKY39_RS26135	COG2807	transmembrane transport
CKY39_RS26160	COG4221	oxidoreductase activity
CKY39_RS26165	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
CKY39_RS26180	COG0583	DNA-binding transcription factor activity
CKY39_RS26215	COG0583	DNA-binding transcription factor activity
CKY39_RS26235	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
CKY39_RS26250	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CKY39_RS26305	COG1960	acyl-CoA dehydrogenase activity
CKY39_RS26320	COG3181	Tripartite tricarboxylate transporter family receptor
CKY39_RS26325	COG4948	Mandelate Racemase Muconate Lactonizing
CKY39_RS26340	COG1028	Short-chain dehydrogenase reductase Sdr
CKY39_RS26345	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CKY39_RS26345	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CKY39_RS26350	COG2267	carboxylic ester hydrolase activity
CKY39_RS26360	COG3022	response to hydroperoxide
CKY39_RS26365	COG0525	valine-tRNA ligase activity
CKY39_RS26375	COG0425	Belongs to the sulfur carrier protein TusA family
CKY39_RS26380	COG2816	NAD+ diphosphatase activity
CKY39_RS26455	COG0559	Belongs to the binding-protein-dependent transport system permease family
CKY39_RS26460	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CKY39_RS26465	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CKY39_RS26470	COG1674	ftsk spoiiie
CKY39_RS26480	COG0492	ferredoxin-NADP+ reductase activity
CKY39_RS26485	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CKY39_RS26490	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CKY39_RS26500	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CKY39_RS26500	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CKY39_RS26520	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CKY39_RS26540	COG1024	Enoyl-CoA hydratase
CKY39_RS26550	COG0196	riboflavin kinase activity
CKY39_RS26560	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CKY39_RS26565	COG1609	Transcriptional regulator
CKY39_RS26585	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CKY39_RS26590	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CKY39_RS26615	COG0745	RESPONSE REGULATOR receiver
CKY39_RS26635	COG2205	protein histidine kinase activity
CKY39_RS26640	COG0745	RESPONSE REGULATOR receiver
CKY39_RS26645	COG4977	sequence-specific DNA binding
CKY39_RS26645	COG1917	Cupin 2, conserved barrel domain protein
CKY39_RS26660	COG1309	transcriptional regulator
CKY39_RS26675	COG0493	'glutamate synthase
CKY39_RS26685	COG1953	Uracil, thiamine, allantoin
CKY39_RS26710	COG1335	isochorismatase
CKY39_RS26715	COG1335	isochorismatase
CKY39_RS26725	COG0670	Belongs to the BI1 family
CKY39_RS26730	COG1959	2 iron, 2 sulfur cluster binding
CKY39_RS26755	COG0589	response to stress
CKY39_RS26780	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CKY39_RS26785	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CKY39_RS26795	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CKY39_RS26830	COG3278	Belongs to the heme-copper respiratory oxidase family
CKY39_RS26840	COG2217	Heavy metal translocating P-type atpase
CKY39_RS26890	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CKY39_RS26895	COG2814	Major facilitator Superfamily
CKY39_RS26900	COG4771	TonB-dependent receptor
CKY39_RS26920	COG5002	protein histidine kinase activity
CKY39_RS26920	COG3447	MASE1 domain protein
CKY39_RS26920	COG5001	Diguanylate cyclase
CKY39_RS26925	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CKY39_RS26970	COG3246	L-lysine catabolic process to acetate
CKY39_RS26985	COG3246	L-lysine catabolic process to acetate
CKY39_RS26990	COG2175	clavaminate synthase activity
CKY39_RS27015	COG2175	clavaminate synthase activity
CKY39_RS27020	COG3246	L-lysine catabolic process to acetate
CKY39_RS27040	COG2855	membrane
CKY39_RS27060	COG4942	peptidase
CKY39_RS27060	COG1388	LysM domain
CKY39_RS27080	COG0318	PFAM AMP-dependent synthetase and ligase
CKY39_RS27100	COG5002	protein histidine kinase activity
CKY39_RS27100	COG0784	Response regulator, receiver
CKY39_RS27175	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CKY39_RS27180	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CKY39_RS27185	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CKY39_RS27200	COG1561	YicC-like family, N-terminal region
CKY39_RS27205	COG0194	GDP metabolic process
CKY39_RS27210	COG1758	RNA polymerase activity
CKY39_RS27215	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CKY39_RS27245	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CKY39_RS27260	COG1420	regulation of RNA biosynthetic process
CKY39_RS27265	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CKY39_RS27325	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CKY39_RS27330	COG0497	DNA recombination
CKY39_RS27335	COG1660	Displays ATPase and GTPase activities
CKY39_RS27345	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CKY39_RS27350	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CKY39_RS27375	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CKY39_RS27380	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CKY39_RS27385	COG0193	aminoacyl-tRNA hydrolase activity
CKY39_RS27395	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CKY39_RS27405	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CKY39_RS27415	COG4608	Belongs to the ABC transporter superfamily
CKY39_RS27425	COG0154	amidase activity
CKY39_RS27445	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CKY39_RS27450	COG0588	phosphoglycerate mutase activity
CKY39_RS27455	COG2267	carboxylic ester hydrolase activity
CKY39_RS27460	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CKY39_RS27465	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CKY39_RS27470	COG1984	allophanate hydrolase subunit 2
CKY39_RS27475	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CKY39_RS27485	COG0742	ribosomal rna small subunit methyltransferase
CKY39_RS27500	COG0612	Peptidase, M16
CKY39_RS27505	COG0612	Peptidase, M16
CKY39_RS27545	COG0583	DNA-binding transcription factor activity
CKY39_RS27555	COG4335	DNA alkylation repair
CKY39_RS27560	COG1999	signal sequence binding
CKY39_RS27565	COG0109	protoheme IX farnesyltransferase activity
CKY39_RS27600	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
CKY39_RS27605	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CKY39_RS27620	COG2226	methyltransferase
CKY39_RS27630	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CKY39_RS27645	COG0489	protein tyrosine kinase activity
CKY39_RS27665	COG3181	Tripartite tricarboxylate transporter family receptor
CKY39_RS27680	COG1024	Enoyl-CoA hydratase
CKY39_RS27700	COG1960	acyl-CoA dehydrogenase activity
CKY39_RS27715	COG2764	glyoxalase bleomycin resistance protein dioxygenase
CKY39_RS27735	COG5507	3-demethylubiquinone-9 3-methyltransferase
CKY39_RS27745	COG2186	Transcriptional regulator
CKY39_RS27750	COG0154	amidase activity
CKY39_RS27770	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CKY39_RS27780	COG0430	RNA-3'-phosphate cyclase activity
CKY39_RS27795	COG1690	Belongs to the RtcB family
CKY39_RS27805	COG4650	regulator
CKY39_RS27820	COG1073	alpha beta
CKY39_RS27830	COG4771	TonB-dependent receptor
CKY39_RS27845	COG0179	Fumarylacetoacetate (FAA) hydrolase
CKY39_RS27850	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CKY39_RS27870	COG0601	transmembrane transport
CKY39_RS27900	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CKY39_RS27905	COG0583	DNA-binding transcription factor activity
CKY39_RS27910	COG1012	belongs to the aldehyde dehydrogenase family
CKY39_RS27920	COG1028	Short-chain dehydrogenase reductase Sdr
CKY39_RS27935	COG0395	ABC-type sugar transport system, permease component
CKY39_RS27940	COG0693	protein deglycase activity
CKY39_RS27955	COG3181	Tripartite tricarboxylate transporter family receptor
CKY39_RS27965	COG0183	Belongs to the thiolase family
CKY39_RS27970	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CKY39_RS27980	COG1414	Transcriptional regulator
CKY39_RS27990	COG3063	Type IV pilus biogenesis stability protein PilW
CKY39_RS28015	COG4964	Belongs to the GSP D family
CKY39_RS28075	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CKY39_RS28080	COG2274	protein secretion by the type I secretion system
CKY39_RS28090	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CKY39_RS28110	COG0583	DNA-binding transcription factor activity
CKY39_RS28115	COG3485	protocatechuate 3,4-dioxygenase
CKY39_RS28120	COG3485	protocatechuate 3,4-dioxygenase
CKY39_RS28130	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CKY39_RS28185	COG1902	pentaerythritol trinitrate reductase activity
CKY39_RS28190	COG0697	spore germination
CKY39_RS28220	COG1028	Short-chain dehydrogenase reductase Sdr
CKY39_RS28225	COG1053	succinate dehydrogenase
CKY39_RS28240	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CKY39_RS28245	COG0540	Belongs to the ATCase OTCase family
CKY39_RS28250	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CKY39_RS28255	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CKY39_RS28260	COG1678	Uncharacterized ACR, COG1678
CKY39_RS28265	COG0415	Belongs to the DNA photolyase family
CKY39_RS28295	COG1773	rubredoxin
CKY39_RS28305	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CKY39_RS28310	COG0154	amidase activity
CKY39_RS28315	COG3181	Tripartite tricarboxylate transporter family receptor
CKY39_RS28330	COG0138	bifunctional purine biosynthesis protein purh
CKY39_RS28335	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CKY39_RS28345	COG1238	metal cluster binding
CKY39_RS28355	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CKY39_RS28370	COG0012	GTP binding
CKY39_RS28375	COG1879	ABC-type sugar transport system periplasmic component
CKY39_RS28380	COG1129	ABC transporter
CKY39_RS28385	COG1172	Belongs to the binding-protein-dependent transport system permease family
CKY39_RS28390	COG1609	Transcriptional regulator
CKY39_RS28400	COG1869	D-ribose catabolic process
CKY39_RS28410	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CKY39_RS28430	COG1024	Enoyl-CoA hydratase
CKY39_RS28480	COG5297	Belongs to the glycosyl hydrolase family 6
CKY39_RS28480	COG4733	cellulase activity
CKY39_RS28495	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CKY39_RS28500	COG4569	acetaldehyde dehydrogenase (acetylating) activity
CKY39_RS28545	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
CKY39_RS28580	COG1960	acyl-CoA dehydrogenase activity
CKY39_RS28585	COG1960	acyl-CoA dehydrogenase activity
CKY39_RS28630	COG0318	PFAM AMP-dependent synthetase and ligase
CKY39_RS28685	COG1024	Enoyl-CoA hydratase
CKY39_RS28730	COG0183	Belongs to the thiolase family
CKY39_RS28735	COG1024	Enoyl-CoA hydratase
CKY39_RS28745	COG0318	PFAM AMP-dependent synthetase and ligase
CKY39_RS28755	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CKY39_RS28765	COG1846	Transcriptional regulator
CKY39_RS28775	COG1024	Enoyl-CoA hydratase
CKY39_RS28795	COG1946	Acyl-CoA thioesterase
CKY39_RS28800	COG1250	3-hydroxyacyl-CoA dehydrogenase
CKY39_RS28800	COG1024	Enoyl-CoA hydratase
CKY39_RS28805	COG0183	Belongs to the thiolase family
CKY39_RS28810	COG2909	trisaccharide binding
CKY39_RS28820	COG1028	Short-chain dehydrogenase reductase Sdr
CKY39_RS28835	COG0318	PFAM AMP-dependent synthetase and ligase
CKY39_RS28840	COG0318	PFAM AMP-dependent synthetase and ligase
CKY39_RS28845	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CKY39_RS28855	COG1024	Enoyl-CoA hydratase
CKY39_RS28865	COG1960	acyl-CoA dehydrogenase activity
CKY39_RS28870	COG1960	acyl-CoA dehydrogenase activity
CKY39_RS28895	COG2255	four-way junction helicase activity
CKY39_RS28900	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CKY39_RS28905	COG2267	carboxylic ester hydrolase activity
CKY39_RS28910	COG2453	phosphatase
CKY39_RS28910	COG0671	phosphoesterase, PA-phosphatase related
CKY39_RS28925	COG4589	Belongs to the CDS family
CKY39_RS28935	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CKY39_RS28990	COG1012	belongs to the aldehyde dehydrogenase family
CKY39_RS29005	COG0632	four-way junction helicase activity
CKY39_RS29010	COG1702	phosphate starvation-inducible protein PhoH
CKY39_RS29015	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CKY39_RS29020	COG4106	trans-aconitate 2-methyltransferase activity
CKY39_RS29025	COG1490	D-aminoacyl-tRNA deacylase activity
CKY39_RS29030	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CKY39_RS29045	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CKY39_RS29055	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CKY39_RS29060	COG2814	Major facilitator Superfamily
CKY39_RS29065	COG0316	Belongs to the HesB IscA family
CKY39_RS29070	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CKY39_RS29075	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CKY39_RS29090	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CKY39_RS29095	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CKY39_RS29105	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CKY39_RS29110	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CKY39_RS29130	COG3243	poly(R)-hydroxyalkanoic acid synthase
CKY39_RS29145	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CKY39_RS29170	COG4555	ABC transporter
CKY39_RS29200	COG2423	ornithine cyclodeaminase activity
CKY39_RS29205	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CKY39_RS29210	COG0683	leucine binding
CKY39_RS29240	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CKY39_RS29245	COG2146	nitrite reductase [NAD(P)H] activity
CKY39_RS29250	COG2116	formate transmembrane transporter activity
CKY39_RS29255	COG0515	serine threonine protein kinase
CKY39_RS29255	COG2815	serine threonine protein kinase
CKY39_RS29265	COG1254	Belongs to the acylphosphatase family
CKY39_RS29275	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CKY39_RS29290	COG1414	Transcriptional regulator
CKY39_RS29325	COG1024	Enoyl-CoA hydratase
CKY39_RS29330	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CKY39_RS29335	COG0318	PFAM AMP-dependent synthetase and ligase
CKY39_RS29340	COG1960	acyl-CoA dehydrogenase activity
CKY39_RS29355	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CKY39_RS29360	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CKY39_RS29365	COG3012	SEC-C Motif Domain Protein
CKY39_RS29380	COG1960	acyl-CoA dehydrogenase activity
CKY39_RS29390	COG0183	Belongs to the thiolase family
CKY39_RS29395	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
CKY39_RS29400	COG0288	reversible hydration of carbon dioxide
CKY39_RS29405	COG0789	Transcriptional regulator
CKY39_RS29420	COG0564	pseudouridine synthase activity
CKY39_RS29445	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CKY39_RS29460	COG1597	lipid kinase activity
CKY39_RS29470	COG0671	phosphoesterase, PA-phosphatase related
CKY39_RS29485	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CKY39_RS29500	COG1522	sequence-specific DNA binding
CKY39_RS29515	COG3186	Phenylalanine-4-hydroxylase
CKY39_RS29520	COG0318	PFAM AMP-dependent synthetase and ligase
CKY39_RS29555	COG0488	(ABC) transporter
CKY39_RS29560	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CKY39_RS29605	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CKY39_RS29645	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CKY39_RS29670	COG0439	Biotin carboxylase
CKY39_RS29675	COG0318	PFAM AMP-dependent synthetase and ligase
CKY39_RS29690	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CKY39_RS29690	COG2124	cytochrome p450
CKY39_RS29720	COG1505	serine-type exopeptidase activity
CKY39_RS29725	COG0010	Belongs to the arginase family
CKY39_RS29735	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CKY39_RS29750	COG1802	Transcriptional regulator
CKY39_RS29755	COG0179	Fumarylacetoacetate (FAA) hydrolase
CKY39_RS29765	COG0346	lactoylglutathione lyase activity
CKY39_RS29770	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CKY39_RS29785	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CKY39_RS29795	COG0778	Nitroreductase
CKY39_RS29820	COG2084	Dehydrogenase
CKY39_RS29830	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CKY39_RS29835	COG0792	nuclease activity
CKY39_RS29840	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CKY39_RS29860	COG1309	transcriptional regulator
CKY39_RS29865	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CKY39_RS29870	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CKY39_RS29920	COG3118	belongs to the thioredoxin family
CKY39_RS29940	COG1879	ABC-type sugar transport system periplasmic component
CKY39_RS29945	COG1172	Belongs to the binding-protein-dependent transport system permease family
CKY39_RS29960	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CKY39_RS29965	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CKY39_RS29970	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CKY39_RS29975	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CKY39_RS29980	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CKY39_RS29985	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CKY39_RS29995	COG0356	it plays a direct role in the translocation of protons across the membrane
CKY39_RS30010	COG2921	Belongs to the UPF0250 family
CKY39_RS30015	COG0321	lipoyl(octanoyl) transferase activity
CKY39_RS30020	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CKY39_RS30035	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CKY39_RS30040	COG0142	geranyltranstransferase activity
CKY39_RS30070	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CKY39_RS30075	COG1012	belongs to the aldehyde dehydrogenase family
CKY39_RS30085	COG2271	Major facilitator Superfamily
CKY39_RS30105	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CKY39_RS30140	COG2130	NADP-dependent
CKY39_RS30175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CKY39_RS30180	COG1136	(ABC) transporter
CKY39_RS30180	COG0577	efflux transmembrane transporter activity
CKY39_RS30185	COG1538	Outer membrane efflux protein
CKY39_RS30190	COG5002	protein histidine kinase activity
CKY39_RS30220	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CKY39_RS30225	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CKY39_RS30240	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CKY39_RS30245	COG3909	cytochrome
CKY39_RS30260	COG0678	peroxiredoxin activity
CKY39_RS30265	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CKY39_RS30270	COG0255	Belongs to the universal ribosomal protein uL29 family
CKY39_RS30275	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CKY39_RS30280	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CKY39_RS30285	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CKY39_RS30290	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CKY39_RS30295	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CKY39_RS30300	COG0089	rRNA binding
CKY39_RS30305	COG0088	Forms part of the polypeptide exit tunnel
CKY39_RS30310	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CKY39_RS30325	COG0051	transcription antitermination factor activity, RNA binding
CKY39_RS30330	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CKY39_RS30335	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CKY39_RS30340	COG0049	tRNA binding
CKY39_RS30345	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CKY39_RS30350	COG1686	Belongs to the peptidase S11 family
CKY39_RS30380	COG0598	Magnesium transport protein CorA
CKY39_RS30390	COG0583	DNA-binding transcription factor activity
CKY39_RS30395	COG0412	Dienelactone hydrolase
CKY39_RS30405	COG1028	Short-chain dehydrogenase reductase Sdr
CKY39_RS30410	COG2095	MarC family integral membrane protein
CKY39_RS30425	COG1022	Amp-dependent synthetase and ligase
CKY39_RS30445	COG0559	Belongs to the binding-protein-dependent transport system permease family
CKY39_RS30455	COG0657	acetylesterase activity
CKY39_RS30460	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CKY39_RS30465	COG1250	3-hydroxyacyl-CoA dehydrogenase
CKY39_RS30480	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CKY39_RS30485	COG1652	LysM domain
CKY39_RS30505	COG1172	Belongs to the binding-protein-dependent transport system permease family
CKY39_RS30510	COG1129	ABC transporter
CKY39_RS30520	COG1172	Belongs to the binding-protein-dependent transport system permease family
CKY39_RS30530	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CKY39_RS30555	COG0640	Transcriptional regulator
CKY39_RS30565	COG0574	Belongs to the PEP-utilizing enzyme family
CKY39_RS30565	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CKY39_RS30580	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CKY39_RS30590	COG4208	sulfate ABC transporter
CKY39_RS30595	COG3842	ATPase activity
CKY39_RS30615	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CKY39_RS30625	COG0640	Transcriptional regulator
CKY39_RS30640	COG0625	glutathione transferase activity
CKY39_RS30650	COG1131	(ABC) transporter
CKY39_RS30655	COG0842	Transport permease protein
CKY39_RS30670	COG1846	Transcriptional regulator
CKY39_RS30675	COG1764	response to oxidative stress
CKY39_RS30685	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CKY39_RS30690	COG0583	DNA-binding transcription factor activity
CKY39_RS30695	COG1960	acyl-CoA dehydrogenase activity
CKY39_RS30715	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CKY39_RS30725	COG3552	Protein containing von Willebrand factor type A (VWA) domain
CKY39_RS30735	COG0714	Associated with various cellular activities
CKY39_RS30755	COG0326	Molecular chaperone. Has ATPase activity
CKY39_RS30760	COG1840	ABC-type Fe3 transport system, periplasmic component
CKY39_RS30765	COG0583	DNA-binding transcription factor activity
CKY39_RS30775	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CKY39_RS30785	COG0642	Histidine kinase
CKY39_RS30800	COG1187	pseudouridine synthase activity
CKY39_RS30805	COG1056	cytidyltransferase-related domain
CKY39_RS30805	COG1051	belongs to the nudix hydrolase family
CKY39_RS30815	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CKY39_RS30850	COG1024	Enoyl-CoA hydratase
CKY39_RS30860	COG0745	RESPONSE REGULATOR receiver
CKY39_RS30875	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CKY39_RS30880	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CKY39_RS30885	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CKY39_RS30910	COG2391	methyltransferase activity
CKY39_RS30945	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CKY39_RS30950	COG4654	Cytochrome c, class I
CKY39_RS30980	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CKY39_RS30995	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CKY39_RS31025	COG1028	Short-chain dehydrogenase reductase Sdr
CKY39_RS31035	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CKY39_RS31040	COG1022	Amp-dependent synthetase and ligase
CKY39_RS31070	COG0318	PFAM AMP-dependent synthetase and ligase
CKY39_RS31125	COG1940	carbohydrate kinase activity
CKY39_RS31130	COG1129	ABC transporter
CKY39_RS31135	COG4214	carbohydrate transport
CKY39_RS31140	COG4213	ABC transporter substrate-binding protein
CKY39_RS31145	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CKY39_RS31150	COG0022	dehydrogenase e1 component
CKY39_RS31160	COG1028	Short-chain dehydrogenase reductase Sdr
CKY39_RS31165	COG0583	DNA-binding transcription factor activity
CKY39_RS31180	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CKY39_RS31195	COG1024	Enoyl-CoA hydratase
CKY39_RS31200	COG1960	acyl-CoA dehydrogenase activity
CKY39_RS31225	COG4695	Portal protein
CKY39_RS31265	COG3179	chitinase
CKY39_RS31430	COG0203	ribosomal protein L17
CKY39_RS31435	COG0202	RNA polymerase activity
CKY39_RS31440	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CKY39_RS31445	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CKY39_RS31450	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CKY39_RS31455	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CKY39_RS31460	COG0201	protein transport
CKY39_RS31465	COG0200	Binds to the 23S rRNA
CKY39_RS31470	COG1841	ribosomal large subunit assembly
CKY39_RS31475	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CKY39_RS31480	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CKY39_RS31485	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CKY39_RS31490	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CKY39_RS31495	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CKY39_RS31500	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CKY39_RS31505	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CKY39_RS31510	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CKY39_RS31525	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CKY39_RS31530	COG0783	Belongs to the Dps family
CKY39_RS31705	COG4770	biotin carboxylase activity
CKY39_RS31710	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CKY39_RS31715	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CKY39_RS31720	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CKY39_RS31765	COG1280	lysine exporter protein (LysE YggA)
CKY39_RS31770	COG1760	l-serine dehydratase
CKY39_RS31775	COG1840	ABC-type Fe3 transport system, periplasmic component
CKY39_RS31785	COG3842	ATPase activity
CKY39_RS31790	COG0583	DNA-binding transcription factor activity
CKY39_RS31795	COG0560	Phosphoserine phosphatase
CKY39_RS31800	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CKY39_RS31805	COG1090	epimerase
CKY39_RS31815	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CKY39_RS31820	COG0343	queuine tRNA-ribosyltransferase activity
CKY39_RS31870	COG0284	orotidine-5'-phosphate decarboxylase activity
CKY39_RS31885	COG1214	PFAM Peptidase M22, glycoprotease
CKY39_RS31895	COG1349	DNA-binding transcription factor activity
CKY39_RS31900	COG0494	nUDIX hydrolase
CKY39_RS31905	COG2027	D-alanyl-D-alanine carboxypeptidase
CKY39_RS31915	COG0009	L-threonylcarbamoyladenylate synthase
CKY39_RS31920	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CKY39_RS31935	COG3620	sequence-specific DNA binding
CKY39_RS31940	COG3550	peptidyl-serine autophosphorylation
CKY39_RS31950	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CKY39_RS31960	COG1522	sequence-specific DNA binding
CKY39_RS31965	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CKY39_RS31970	COG0469	pyruvate kinase activity
CKY39_RS31975	COG0126	phosphoglycerate kinase activity
CKY39_RS31995	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CKY39_RS32025	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CKY39_RS32035	COG0242	peptide deformylase activity
CKY39_RS32045	COG0758	DNA mediated transformation
CKY39_RS32050	COG2922	Belongs to the Smg family
CKY39_RS32060	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CKY39_RS32065	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CKY39_RS32070	COG1862	Preprotein translocase
CKY39_RS32080	COG1522	sequence-specific DNA binding
CKY39_RS32110	COG0765	amino acid transport
CKY39_RS32115	COG2814	Major facilitator Superfamily
CKY39_RS32125	COG1845	cytochrome c oxidase, subunit III
CKY39_RS32135	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CKY39_RS32140	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CKY39_RS32165	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CKY39_RS32195	COG0251	oxidation-reduction process
CKY39_RS32205	COG3622	Belongs to the hyi family
CKY39_RS32210	COG0235	Class ii aldolase
CKY39_RS32215	COG3395	kinase activity
CKY39_RS32220	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CKY39_RS32225	COG2084	Dehydrogenase
CKY39_RS32230	COG2271	Major facilitator Superfamily
CKY39_RS32235	COG2186	Transcriptional regulator
CKY39_RS32245	COG1522	sequence-specific DNA binding
CKY39_RS32280	COG4566	intracellular signal transduction
CKY39_RS32300	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CKY39_RS32305	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CKY39_RS32310	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CKY39_RS32315	COG1595	DNA-templated transcription, initiation
CKY39_RS32330	COG0625	glutathione transferase activity
CKY39_RS32345	COG4772	TonB-dependent receptor
CKY39_RS32365	COG0861	Integral membrane protein TerC family
CKY39_RS32375	COG1950	PFAM Membrane protein of
CKY39_RS32380	COG4783	chaperone-mediated protein folding
CKY39_RS32385	COG0315	cyclic pyranopterin monophosphate synthase activity
CKY39_RS32390	COG3307	-O-antigen
CKY39_RS32455	COG1716	ATPase activity
CKY39_RS32460	COG0631	protein serine/threonine phosphatase activity
CKY39_RS32465	COG0861	Integral membrane protein TerC family
CKY39_RS32470	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CKY39_RS32480	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CKY39_RS32485	COG0427	acetyl-CoA hydrolase
CKY39_RS32490	COG3781	membrane
CKY39_RS32500	COG4682	membrane
CKY39_RS32510	COG2137	regulation of response to DNA damage stimulus
CKY39_RS32515	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CKY39_RS32540	COG0642	Histidine kinase
CKY39_RS32555	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CKY39_RS32555	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CKY39_RS32575	COG0583	DNA-binding transcription factor activity
CKY39_RS32580	COG3181	Tripartite tricarboxylate transporter family receptor
CKY39_RS32605	COG1960	acyl-CoA dehydrogenase activity
CKY39_RS32615	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CKY39_RS32625	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CKY39_RS32630	COG1522	sequence-specific DNA binding
CKY39_RS32640	COG2814	Major facilitator Superfamily
CKY39_RS32645	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CKY39_RS32650	COG0513	Belongs to the DEAD box helicase family
CKY39_RS32665	COG0697	spore germination
CKY39_RS32675	COG1802	Transcriptional regulator
CKY39_RS32710	COG1473	amidohydrolase
CKY39_RS32715	COG1741	Belongs to the pirin family
CKY39_RS32735	COG3025	triphosphatase activity
CKY39_RS32770	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CKY39_RS32775	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CKY39_RS32780	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CKY39_RS32795	COG0006	proline dipeptidase activity
CKY39_RS32825	COG4953	penicillin-binding protein 1C
CKY39_RS32830	COG2373	Large extracellular alpha-helical protein
CKY39_RS32855	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CKY39_RS32875	COG0281	malic enzyme
CKY39_RS32875	COG0280	phosphate acetyltransferase
CKY39_RS32890	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CKY39_RS32895	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CKY39_RS32900	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CKY39_RS32910	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CKY39_RS32925	COG2814	Major facilitator Superfamily
CKY39_RS32930	COG2267	carboxylic ester hydrolase activity
CKY39_RS32950	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CKY39_RS32955	COG1739	Uncharacterized protein family UPF0029
CKY39_RS32960	COG2813	Specifically methylates the guanine in position
CKY39_RS32960	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CKY39_RS32965	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CKY39_RS32970	COG2119	membrane
CKY39_RS32975	COG0724	RNA recognition motif
CKY39_RS32980	COG1028	Short-chain dehydrogenase reductase Sdr
CKY39_RS32990	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CKY39_RS33010	COG2066	Belongs to the glutaminase family
CKY39_RS33010	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
CKY39_RS33020	COG0706	membrane insertase activity
CKY39_RS33025	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CKY39_RS33030	COG0594	ribonuclease P activity
CKY39_RS33035	COG0230	Belongs to the bacterial ribosomal protein bL34 family