locus-tag	class	description
GFK26_RS00025	COG0142	geranyltranstransferase activity
GFK26_RS00055	COG1696	Membrane protein involved in D-alanine export
GFK26_RS00065	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
GFK26_RS00070	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
GFK26_RS00075	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GFK26_RS00075	COG2755	lipolytic protein G-D-S-L family
GFK26_RS00095	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GFK26_RS00130	COG0831	urea catabolic process
GFK26_RS00140	COG0832	Belongs to the urease beta subunit family
GFK26_RS00145	COG0804	urea catabolic process
GFK26_RS00160	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
GFK26_RS00165	COG0830	nickel cation binding
GFK26_RS00170	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
GFK26_RS00180	COG0583	DNA-binding transcription factor activity
GFK26_RS00190	COG0583	DNA-binding transcription factor activity
GFK26_RS00210	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_RS00250	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GFK26_RS00255	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GFK26_RS00270	COG0084	hydrolase, TatD family'
GFK26_RS00275	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GFK26_RS00280	COG0714	Associated with various cellular activities
GFK26_RS00290	COG2304	oxidoreductase activity
GFK26_RS00300	COG0300	oxidoreductase activity
GFK26_RS00305	COG1309	transcriptional regulator
GFK26_RS00315	COG1024	Enoyl-CoA hydratase
GFK26_RS00320	COG2050	protein possibly involved in aromatic compounds catabolism
GFK26_RS00330	COG3396	Phenylacetate-CoA oxygenase
GFK26_RS00335	COG3460	Phenylacetate-CoA oxygenase
GFK26_RS00340	COG3396	Phenylacetate-CoA oxygenase
GFK26_RS00345	COG2151	metal-sulfur cluster biosynthetic enzyme
GFK26_RS00350	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GFK26_RS00375	COG2030	dehydratase
GFK26_RS00375	COG1012	belongs to the aldehyde dehydrogenase family
GFK26_RS00380	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_RS00390	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GFK26_RS00410	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
GFK26_RS00440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GFK26_RS00445	COG0583	DNA-binding transcription factor activity
GFK26_RS00450	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
GFK26_RS00480	COG0601	transmembrane transport
GFK26_RS00500	COG0740	serine-type endopeptidase activity
GFK26_RS00530	COG1136	(ABC) transporter
GFK26_RS00535	COG4591	ABC-type transport system involved in lipoprotein release permease component
GFK26_RS00545	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GFK26_RS00555	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_RS00570	COG3685	Protein conserved in bacteria
GFK26_RS00595	COG0366	Alpha amylase catalytic
GFK26_RS00620	COG2226	methyltransferase
GFK26_RS00640	COG1595	DNA-templated transcription, initiation
GFK26_RS00650	COG1609	Transcriptional regulator
GFK26_RS00655	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GFK26_RS00660	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GFK26_RS00670	COG1850	ribulose-bisphosphate carboxylase activity
GFK26_RS00685	COG2969	positive regulation of protein catabolic process
GFK26_RS00690	COG0625	glutathione transferase activity
GFK26_RS00695	COG2857	Cytochrome c1
GFK26_RS00700	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GFK26_RS00705	COG0723	plastoquinol--plastocyanin reductase activity
GFK26_RS00725	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GFK26_RS00735	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GFK26_RS00740	COG0489	protein tyrosine kinase activity
GFK26_RS00740	COG3206	protein involved in exopolysaccharide biosynthesis
GFK26_RS00755	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GFK26_RS00810	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GFK26_RS00815	COG1596	polysaccharide export
GFK26_RS00820	COG1970	mechanosensitive ion channel activity
GFK26_RS00825	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GFK26_RS00830	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GFK26_RS00845	COG0805	protein transport
GFK26_RS00850	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GFK26_RS00855	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GFK26_RS00860	COG0537	adenosine 5'-monophosphoramidase activity
GFK26_RS00870	COG0140	phosphoribosyl-ATP diphosphatase activity
GFK26_RS00875	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GFK26_RS00880	COG0107	imidazoleglycerol-phosphate synthase activity
GFK26_RS00890	COG1301	dicarboxylic acid transport
GFK26_RS00895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GFK26_RS00900	COG0583	DNA-binding transcription factor activity
GFK26_RS00905	COG2814	Major facilitator Superfamily
GFK26_RS00910	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GFK26_RS00920	COG0131	Imidazoleglycerol-phosphate dehydratase
GFK26_RS00925	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GFK26_RS00945	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GFK26_RS00950	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GFK26_RS00955	COG5007	Belongs to the BolA IbaG family
GFK26_RS00960	COG0842	Transport permease protein
GFK26_RS00965	COG1131	(ABC) transporter
GFK26_RS00980	COG2853	Lipoprotein
GFK26_RS00985	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GFK26_RS00990	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GFK26_RS00995	COG1127	ABC transporter
GFK26_RS01005	COG0070	glutamate synthase
GFK26_RS01005	COG0069	glutamate synthase activity
GFK26_RS01005	COG0067	glutamate synthase
GFK26_RS01030	COG0232	Belongs to the dGTPase family. Type 2 subfamily
GFK26_RS01035	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GFK26_RS01040	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GFK26_RS01075	COG1965	Belongs to the frataxin family
GFK26_RS01080	COG0019	diaminopimelate decarboxylase activity
GFK26_RS01085	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
GFK26_RS01090	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GFK26_RS01095	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GFK26_RS01100	COG1333	cytochrome c biogenesis protein
GFK26_RS01110	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GFK26_RS01120	COG1560	Kdo2-lipid A biosynthetic process
GFK26_RS01130	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GFK26_RS01135	COG4772	TonB-dependent receptor
GFK26_RS01150	COG4774	siderophore transport
GFK26_RS01155	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GFK26_RS01165	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GFK26_RS01170	COG0459	protein refolding
GFK26_RS01175	COG1070	Carbohydrate kinase
GFK26_RS01180	COG2207	Transcriptional regulator
GFK26_RS01180	COG4753	response regulator
GFK26_RS01190	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GFK26_RS01200	COG0246	Mannitol dehydrogenase
GFK26_RS01205	COG3842	ATPase activity
GFK26_RS01210	COG0395	ABC-type sugar transport system, permease component
GFK26_RS01215	COG1175	transmembrane transport
GFK26_RS01245	COG0166	Belongs to the GPI family
GFK26_RS01250	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GFK26_RS01265	COG3842	ATPase activity
GFK26_RS01275	COG1840	ABC-type Fe3 transport system, periplasmic component
GFK26_RS01280	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GFK26_RS01285	COG3384	dioxygenase
GFK26_RS01290	COG4608	Belongs to the ABC transporter superfamily
GFK26_RS01295	COG0444	Belongs to the ABC transporter superfamily
GFK26_RS01300	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GFK26_RS01310	COG1473	amidohydrolase
GFK26_RS01325	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
GFK26_RS01330	COG1765	OsmC-like protein
GFK26_RS01345	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GFK26_RS01430	COG0583	DNA-binding transcription factor activity
GFK26_RS01435	COG2233	PERMEase
GFK26_RS01445	COG2010	Cytochrome c
GFK26_RS01450	COG2863	cytochrome
GFK26_RS01460	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GFK26_RS01465	COG2271	Major facilitator Superfamily
GFK26_RS01475	COG4149	molybdate abc transporter
GFK26_RS01480	COG3842	ATPase activity
GFK26_RS01485	COG1840	ABC-type Fe3 transport system, periplasmic component
GFK26_RS01490	COG4178	(ABC) transporter
GFK26_RS01495	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GFK26_RS01505	COG1132	(ABC) transporter
GFK26_RS01510	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GFK26_RS01510	COG0189	ligase activity
GFK26_RS01515	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GFK26_RS01515	COG0189	ligase activity
GFK26_RS01545	COG1172	Belongs to the binding-protein-dependent transport system permease family
GFK26_RS01550	COG1172	Belongs to the binding-protein-dependent transport system permease family
GFK26_RS01555	COG1129	ABC transporter
GFK26_RS01560	COG4214	carbohydrate transport
GFK26_RS01570	COG4213	ABC transporter substrate-binding protein
GFK26_RS01575	COG1879	ABC-type sugar transport system periplasmic component
GFK26_RS01580	COG1012	belongs to the aldehyde dehydrogenase family
GFK26_RS01590	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_RS01595	COG3386	PFAM SMP-30 Gluconolaconase
GFK26_RS01610	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GFK26_RS01615	COG0583	DNA-binding transcription factor activity
GFK26_RS01620	COG0697	spore germination
GFK26_RS01635	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GFK26_RS01635	COG0506	proline dehydrogenase activity
GFK26_RS01635	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GFK26_RS01645	COG5295	Hep Hag repeat protein
GFK26_RS01655	COG2832	Protein of unknown function (DUF454)
GFK26_RS01670	COG0235	Class ii aldolase
GFK26_RS01675	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GFK26_RS01680	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
GFK26_RS01685	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GFK26_RS01695	COG1012	belongs to the aldehyde dehydrogenase family
GFK26_RS01705	COG0583	DNA-binding transcription factor activity
GFK26_RS01730	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
GFK26_RS01735	COG3387	PFAM Glycoside hydrolase 15-related
GFK26_RS01745	COG0617	tRNA 3'-terminal CCA addition
GFK26_RS01760	COG1285	pathogenesis
GFK26_RS01765	COG0739	heme binding
GFK26_RS01765	COG0741	lytic transglycosylase activity
GFK26_RS01765	COG1196	nuclear chromosome segregation
GFK26_RS01770	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GFK26_RS01775	COG0583	DNA-binding transcription factor activity
GFK26_RS01790	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GFK26_RS01800	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GFK26_RS01810	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GFK26_RS01830	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GFK26_RS01835	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
GFK26_RS01845	COG2175	clavaminate synthase activity
GFK26_RS01855	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_RS01865	COG0037	tRNA processing
GFK26_RS01900	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GFK26_RS01905	COG2205	protein histidine kinase activity
GFK26_RS01915	COG2204	response regulator
GFK26_RS01925	COG3416	Protein conserved in bacteria
GFK26_RS01925	COG2943	transferase activity, transferring hexosyl groups
GFK26_RS01940	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GFK26_RS01945	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GFK26_RS01975	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GFK26_RS01985	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GFK26_RS01995	COG2264	protein methyltransferase activity
GFK26_RS02000	COG0439	Biotin carboxylase
GFK26_RS02005	COG0511	ligase activity, forming carbon-carbon bonds
GFK26_RS02010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GFK26_RS02020	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GFK26_RS02030	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GFK26_RS02040	COG0312	modulator of DNA gyrase
GFK26_RS02045	COG0772	Belongs to the SEDS family
GFK26_RS02055	COG2197	response regulator
GFK26_RS02060	COG3150	esterase
GFK26_RS02075	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GFK26_RS02080	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GFK26_RS02095	COG0575	Belongs to the CDS family
GFK26_RS02105	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GFK26_RS02110	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GFK26_RS02115	COG0583	DNA-binding transcription factor activity
GFK26_RS02120	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
GFK26_RS02135	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GFK26_RS02140	COG1181	Belongs to the D-alanine--D-alanine ligase family
GFK26_RS02145	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GFK26_RS02150	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GFK26_RS02155	COG0772	Belongs to the SEDS family
GFK26_RS02160	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GFK26_RS02165	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GFK26_RS02170	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GFK26_RS02175	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GFK26_RS02190	COG0275	rRNA processing
GFK26_RS02195	COG2001	Belongs to the MraZ family
GFK26_RS02200	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GFK26_RS02205	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GFK26_RS02225	COG0523	cobalamin synthesis protein
GFK26_RS02235	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
GFK26_RS02250	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GFK26_RS02270	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GFK26_RS02280	COG1335	isochorismatase
GFK26_RS02285	COG0583	DNA-binding transcription factor activity
GFK26_RS02320	COG2207	Transcriptional regulator
GFK26_RS02320	COG0662	Cupin 2, conserved barrel domain protein
GFK26_RS02345	COG0656	L-ascorbic acid biosynthetic process
GFK26_RS02365	COG2807	transmembrane transport
GFK26_RS02385	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_RS02390	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GFK26_RS02395	COG1187	pseudouridine synthase activity
GFK26_RS02410	COG1566	PFAM secretion protein HlyD family protein
GFK26_RS02425	COG1846	Transcriptional regulator
GFK26_RS02435	COG3604	Transcriptional regulator
GFK26_RS02450	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
GFK26_RS02465	COG0501	Belongs to the peptidase M48B family
GFK26_RS02485	COG0418	dihydroorotase activity
GFK26_RS02490	COG1595	DNA-templated transcription, initiation
GFK26_RS02510	COG0747	negative chemotaxis
GFK26_RS02515	COG0601	transmembrane transport
GFK26_RS02520	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GFK26_RS02525	COG4608	Belongs to the ABC transporter superfamily
GFK26_RS02530	COG0444	Belongs to the ABC transporter superfamily
GFK26_RS02535	COG0154	amidase activity
GFK26_RS02545	COG1573	uracil-dna glycosylase
GFK26_RS02555	COG0583	DNA-binding transcription factor activity
GFK26_RS02560	COG1250	3-hydroxyacyl-CoA dehydrogenase
GFK26_RS02560	COG1024	Enoyl-CoA hydratase
GFK26_RS02565	COG0183	Belongs to the thiolase family
GFK26_RS02570	COG1960	acyl-CoA dehydrogenase activity
GFK26_RS02575	COG1960	acyl-CoA dehydrogenase activity
GFK26_RS02580	COG1024	Enoyl-CoA hydratase
GFK26_RS02585	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GFK26_RS02595	COG0318	PFAM AMP-dependent synthetase and ligase
GFK26_RS02640	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GFK26_RS02645	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GFK26_RS02655	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GFK26_RS02655	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GFK26_RS02660	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GFK26_RS02665	COG1957	nucleoside hydrolase
GFK26_RS02670	COG1126	abc transporter atp-binding protein
GFK26_RS02675	COG0765	amino acid transport
GFK26_RS02680	COG0765	amino acid transport
GFK26_RS02685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GFK26_RS02690	COG0583	DNA-binding transcription factor activity
GFK26_RS02695	COG0154	amidase activity
GFK26_RS02700	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GFK26_RS02705	COG5265	(ABC) transporter
GFK26_RS02715	COG0683	leucine binding
GFK26_RS02720	COG1024	Enoyl-CoA hydratase
GFK26_RS02740	COG0183	Belongs to the thiolase family
GFK26_RS02745	COG2852	Protein conserved in bacteria
GFK26_RS02750	COG1024	Enoyl-CoA hydratase
GFK26_RS02750	COG1250	3-hydroxyacyl-CoA dehydrogenase
GFK26_RS02760	COG1960	acyl-CoA dehydrogenase activity
GFK26_RS02770	COG4221	oxidoreductase activity
GFK26_RS02775	COG0583	DNA-binding transcription factor activity
GFK26_RS02785	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_RS02790	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_RS02795	COG2186	Transcriptional regulator
GFK26_RS02800	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GFK26_RS02810	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GFK26_RS02815	COG2721	sulfolactate sulfo-lyase activity
GFK26_RS02820	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
GFK26_RS02835	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GFK26_RS02850	COG1215	transferase activity, transferring glycosyl groups
GFK26_RS02855	COG0438	transferase activity, transferring glycosyl groups
GFK26_RS02855	COG1216	Glycosyl transferase, family 2
GFK26_RS02885	COG1215	transferase activity, transferring glycosyl groups
GFK26_RS02895	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GFK26_RS02905	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GFK26_RS02930	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GFK26_RS02955	COG0697	spore germination
GFK26_RS02965	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GFK26_RS02980	COG0384	phenazine biosynthesis protein PhzF
GFK26_RS02985	COG0625	glutathione transferase activity
GFK26_RS02990	COG0384	phenazine biosynthesis protein PhzF
GFK26_RS03005	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GFK26_RS03020	COG0726	polysaccharide deacetylase
GFK26_RS03020	COG1649	PFAM Uncharacterised BCR, COG1649
GFK26_RS03025	COG1215	transferase activity, transferring glycosyl groups
GFK26_RS03035	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_RS03040	COG0583	DNA-binding transcription factor activity
GFK26_RS03080	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GFK26_RS03085	COG4232	protein-disulfide reductase activity
GFK26_RS03090	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GFK26_RS03105	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GFK26_RS03110	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GFK26_RS03130	COG0679	Auxin Efflux Carrier
GFK26_RS03135	COG0210	DNA helicase
GFK26_RS03150	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GFK26_RS03180	COG3121	Chaperone
GFK26_RS03185	COG3188	usher protein
GFK26_RS03230	COG0582	viral genome integration into host DNA
GFK26_RS03260	COG4983	Phage plasmid primase, P4 family domain protein
GFK26_RS03275	COG0484	heat shock protein binding
GFK26_RS03400	COG4974	Belongs to the 'phage' integrase family
GFK26_RS03405	COG0582	viral genome integration into host DNA
GFK26_RS03410	COG4974	Belongs to the 'phage' integrase family
GFK26_RS03440	COG0583	DNA-binding transcription factor activity
GFK26_RS03530	COG0789	Transcriptional regulator
GFK26_RS03555	COG1785	Belongs to the alkaline phosphatase family
GFK26_RS03560	COG1785	Belongs to the alkaline phosphatase family
GFK26_RS03625	COG1929	Belongs to the glycerate kinase type-1 family
GFK26_RS03630	COG4232	protein-disulfide reductase activity
GFK26_RS03660	COG2433	Pfam Transposase IS66
GFK26_RS03685	COG0785	Cytochrome C biogenesis protein
GFK26_RS03690	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GFK26_RS03700	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GFK26_RS03705	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GFK26_RS03710	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GFK26_RS03715	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GFK26_RS03735	COG0789	Transcriptional regulator
GFK26_RS03780	COG0723	plastoquinol--plastocyanin reductase activity
GFK26_RS03790	COG0347	Belongs to the P(II) protein family
GFK26_RS03810	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GFK26_RS03835	COG2132	Multicopper oxidase
GFK26_RS03850	COG3387	PFAM Glycoside hydrolase 15-related
GFK26_RS03965	COG0583	DNA-binding transcription factor activity
GFK26_RS03980	COG2204	response regulator
GFK26_RS03985	COG5000	phosphorelay sensor kinase activity
GFK26_RS03995	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GFK26_RS03995	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GFK26_RS04005	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GFK26_RS04010	COG0085	RNA polymerase activity
GFK26_RS04015	COG0222	ribosome binding
GFK26_RS04020	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GFK26_RS04025	COG0081	regulation of translation
GFK26_RS04030	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GFK26_RS04040	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GFK26_RS04050	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GFK26_RS04070	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GFK26_RS04075	COG0134	indole-3-glycerol-phosphate synthase activity
GFK26_RS04080	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GFK26_RS04110	COG0546	phosphoglycolate phosphatase activity
GFK26_RS04115	COG0583	DNA-binding transcription factor activity
GFK26_RS04120	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_RS04140	COG1538	Outer membrane efflux protein
GFK26_RS04345	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
GFK26_RS04350	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
GFK26_RS04365	COG5002	protein histidine kinase activity
GFK26_RS04385	COG3210	domain, Protein
GFK26_RS04415	COG0753	catalase activity
GFK26_RS04430	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GFK26_RS04435	COG2967	ApaG domain
GFK26_RS04450	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
GFK26_RS04455	COG4977	sequence-specific DNA binding
GFK26_RS04460	COG1335	isochorismatase
GFK26_RS04485	COG0583	DNA-binding transcription factor activity
GFK26_RS04490	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_RS04520	COG2197	response regulator
GFK26_RS04545	COG0069	glutamate synthase activity
GFK26_RS04585	COG2353	YceI-like domain
GFK26_RS04595	COG1280	lysine exporter protein (LysE YggA)
GFK26_RS04600	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GFK26_RS04605	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GFK26_RS04610	COG1137	ATPase activity
GFK26_RS04615	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
GFK26_RS04620	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GFK26_RS04630	COG0018	arginyl-trna synthetase
GFK26_RS04650	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GFK26_RS04655	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GFK26_RS04660	COG1414	Transcriptional regulator
GFK26_RS04665	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GFK26_RS04675	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GFK26_RS04695	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
GFK26_RS04700	COG0583	DNA-binding transcription factor activity
GFK26_RS04715	COG0205	6-phosphofructokinase activity
GFK26_RS04730	COG2814	Major facilitator Superfamily
GFK26_RS04750	COG0154	amidase activity
GFK26_RS04755	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_RS04770	COG0121	glutamine amidotransferase
GFK26_RS04785	COG0189	ligase activity
GFK26_RS04790	COG3135	benzoate transporter
GFK26_RS04795	COG3158	transport of potassium into the cell
GFK26_RS04805	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GFK26_RS04820	COG0495	leucyl-tRNA aminoacylation
GFK26_RS04825	COG2072	flavoprotein involved in K transport
GFK26_RS04830	COG0366	Alpha amylase catalytic
GFK26_RS04845	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GFK26_RS04850	COG0297	glycogen (starch) synthase activity
GFK26_RS04855	COG0058	SHG alpha-glucan phosphorylase activity
GFK26_RS04870	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GFK26_RS04875	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GFK26_RS04880	COG0735	belongs to the Fur family
GFK26_RS04885	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GFK26_RS04895	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GFK26_RS04920	COG0747	negative chemotaxis
GFK26_RS04925	COG4608	Belongs to the ABC transporter superfamily
GFK26_RS04930	COG0444	Belongs to the ABC transporter superfamily
GFK26_RS04935	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GFK26_RS04940	COG0601	transmembrane transport
GFK26_RS04945	COG0318	PFAM AMP-dependent synthetase and ligase
GFK26_RS04960	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GFK26_RS04980	COG0482	sulfurtransferase activity
GFK26_RS04985	COG0318	PFAM AMP-dependent synthetase and ligase
GFK26_RS04990	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GFK26_RS05025	COG0629	single-stranded DNA binding
GFK26_RS05065	COG2188	Transcriptional regulator
GFK26_RS05070	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GFK26_RS05075	COG1070	Carbohydrate kinase
GFK26_RS05090	COG1172	Belongs to the binding-protein-dependent transport system permease family
GFK26_RS05095	COG0667	Aldo Keto reductase
GFK26_RS05130	COG0411	ABC transporter
GFK26_RS05135	COG1129	ABC transporter
GFK26_RS05140	COG0659	secondary active sulfate transmembrane transporter activity
GFK26_RS05155	COG1946	Acyl-CoA thioesterase
GFK26_RS05165	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GFK26_RS05170	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_RS05180	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GFK26_RS05195	COG0583	DNA-binding transcription factor activity
GFK26_RS05225	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GFK26_RS05235	COG1879	ABC-type sugar transport system periplasmic component
GFK26_RS05245	COG1172	Belongs to the binding-protein-dependent transport system permease family
GFK26_RS05250	COG1063	alcohol dehydrogenase
GFK26_RS05255	COG1070	Carbohydrate kinase
GFK26_RS05260	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_RS05275	COG0243	molybdopterin cofactor binding
GFK26_RS05290	COG1473	amidohydrolase
GFK26_RS05295	COG0584	glycerophosphoryl diester phosphodiesterase
GFK26_RS05305	COG2733	membrane
GFK26_RS05320	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GFK26_RS05325	COG0439	Biotin carboxylase
GFK26_RS05335	COG1960	acyl-CoA dehydrogenase activity
GFK26_RS05340	COG1960	acyl-CoA dehydrogenase activity
GFK26_RS05345	COG0513	Belongs to the DEAD box helicase family
GFK26_RS05350	COG0023	Translation Initiation Factor
GFK26_RS05360	COG0724	RNA recognition motif
GFK26_RS05380	COG0004	ammonium transporteR
GFK26_RS05390	COG0028	Belongs to the TPP enzyme family
GFK26_RS05395	COG0436	Aminotransferase
GFK26_RS05410	COG2827	Endonuclease containing a URI domain
GFK26_RS05425	COG0583	DNA-binding transcription factor activity
GFK26_RS05430	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GFK26_RS05435	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GFK26_RS05460	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GFK26_RS05475	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GFK26_RS05485	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
GFK26_RS05495	COG0179	Fumarylacetoacetate (FAA) hydrolase
GFK26_RS05500	COG0768	penicillin binding
GFK26_RS05510	COG1792	Involved in formation and maintenance of cell shape
GFK26_RS05515	COG1077	Cell shape determining protein MreB Mrl
GFK26_RS05520	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GFK26_RS05525	COG0154	amidase activity
GFK26_RS05530	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GFK26_RS05540	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GFK26_RS05545	COG0708	Exodeoxyribonuclease III
GFK26_RS05565	COG0501	Belongs to the peptidase M48B family
GFK26_RS05570	COG2211	Major facilitator Superfamily
GFK26_RS05585	COG0579	oxidoreductase
GFK26_RS05590	COG0745	RESPONSE REGULATOR receiver
GFK26_RS05620	COG2974	May be involved in recombination
GFK26_RS05635	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GFK26_RS05645	COG1846	Transcriptional regulator
GFK26_RS05665	COG1012	belongs to the aldehyde dehydrogenase family
GFK26_RS05670	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_RS05690	COG3971	2-oxopent-4-enoate hydratase activity
GFK26_RS05700	COG0129	dihydroxy-acid dehydratase activity
GFK26_RS05715	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GFK26_RS05725	COG0217	transcriptional regulatory protein
GFK26_RS05735	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GFK26_RS05750	COG0386	Belongs to the glutathione peroxidase family
GFK26_RS05760	COG0247	lactate metabolic process
GFK26_RS05765	COG0277	FAD linked oxidase domain protein
GFK26_RS05770	COG0277	FAD linked oxidase domain protein
GFK26_RS05775	COG1620	l-lactate permease
GFK26_RS05780	COG0583	DNA-binding transcription factor activity
GFK26_RS05790	COG0004	ammonium transporteR
GFK26_RS05795	COG0347	Belongs to the P(II) protein family
GFK26_RS05950	COG2080	2 iron, 2 sulfur cluster binding
GFK26_RS05955	COG1335	isochorismatase
GFK26_RS05975	COG0683	leucine binding
GFK26_RS06005	COG1309	transcriptional regulator
GFK26_RS06030	COG1410	methionine synthase
GFK26_RS06030	COG0646	methionine synthase
GFK26_RS06035	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
GFK26_RS06040	COG5380	lipid catabolic process
GFK26_RS06075	COG1228	amidohydrolase
GFK26_RS06085	COG0765	amino acid transport
GFK26_RS06090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GFK26_RS06105	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GFK26_RS06110	COG2986	histidine ammonia-lyase
GFK26_RS06120	COG1116	anion transmembrane transporter activity
GFK26_RS06125	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GFK26_RS06155	COG1070	Carbohydrate kinase
GFK26_RS06170	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GFK26_RS06175	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GFK26_RS06180	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
GFK26_RS06245	COG0633	Ferredoxin
GFK26_RS06250	COG0683	leucine binding
GFK26_RS06270	COG0410	ABC transporter
GFK26_RS06285	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GFK26_RS06290	COG0700	Nucleoside recognition
GFK26_RS06295	COG2015	COG2015, Alkyl sulfatase and related hydrolases
GFK26_RS06305	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GFK26_RS06320	COG2066	Belongs to the glutaminase family
GFK26_RS06350	COG0559	Belongs to the binding-protein-dependent transport system permease family
GFK26_RS06355	COG1129	ABC transporter
GFK26_RS06365	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GFK26_RS06375	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GFK26_RS06400	COG0583	DNA-binding transcription factor activity
GFK26_RS06415	COG1573	uracil-dna glycosylase
GFK26_RS06425	COG1760	l-serine dehydratase
GFK26_RS06430	COG1473	amidohydrolase
GFK26_RS06440	COG0583	DNA-binding transcription factor activity
GFK26_RS06455	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GFK26_RS06460	COG1960	acyl-CoA dehydrogenase activity
GFK26_RS06465	COG0583	DNA-binding transcription factor activity
GFK26_RS06480	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
GFK26_RS06490	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GFK26_RS06505	COG1116	anion transmembrane transporter activity
GFK26_RS06505	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GFK26_RS06510	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GFK26_RS06515	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GFK26_RS06520	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
GFK26_RS06540	COG1959	2 iron, 2 sulfur cluster binding
GFK26_RS06570	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GFK26_RS06625	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_RS06630	COG1942	4-Oxalocrotonate Tautomerase
GFK26_RS06635	COG3284	Transcriptional regulator
GFK26_RS06640	COG1819	glycosyl
GFK26_RS06645	COG1309	transcriptional regulator
GFK26_RS06665	COG3246	L-lysine catabolic process to acetate
GFK26_RS06675	COG1250	3-hydroxyacyl-CoA dehydrogenase
GFK26_RS06690	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GFK26_RS06715	COG2050	protein possibly involved in aromatic compounds catabolism
GFK26_RS06720	COG2233	PERMEase
GFK26_RS06730	COG2894	cell division
GFK26_RS06735	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
GFK26_RS06755	COG0583	DNA-binding transcription factor activity
GFK26_RS06770	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GFK26_RS06835	COG2096	Adenosyltransferase
GFK26_RS06845	COG0277	FAD linked oxidase domain protein
GFK26_RS06865	COG1192	Involved in chromosome partitioning
GFK26_RS06875	COG0357	Ribosomal RNA small subunit methyltransferase G
GFK26_RS06880	COG0445	tRNA wobble uridine modification
GFK26_RS06890	COG5487	UPF0391 membrane protein
GFK26_RS06900	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GFK26_RS06905	COG1024	Enoyl-CoA hydratase
GFK26_RS06910	COG1024	Enoyl-CoA hydratase
GFK26_RS06920	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_RS06930	COG1902	pentaerythritol trinitrate reductase activity
GFK26_RS06965	COG0456	acetyltransferase
GFK26_RS06970	COG0642	Histidine kinase
GFK26_RS06975	COG0745	RESPONSE REGULATOR receiver
GFK26_RS06985	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GFK26_RS07000	COG2217	Heavy metal translocating P-type atpase
GFK26_RS07005	COG2608	mercury ion transmembrane transporter activity
GFK26_RS07020	COG0745	RESPONSE REGULATOR receiver
GFK26_RS07025	COG2205	protein histidine kinase activity
GFK26_RS07040	COG1472	Belongs to the glycosyl hydrolase 3 family
GFK26_RS07065	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GFK26_RS07070	COG0456	acetyltransferase
GFK26_RS07070	COG0454	-acetyltransferase
GFK26_RS07095	COG3568	Endonuclease Exonuclease Phosphatase
GFK26_RS07100	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GFK26_RS07105	COG0392	lysyltransferase activity
GFK26_RS07115	COG1408	metallophosphoesterase
GFK26_RS07150	COG0592	DNA-directed DNA polymerase activity
GFK26_RS07155	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GFK26_RS07160	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GFK26_RS07165	COG0594	ribonuclease P activity
GFK26_RS07170	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GFK26_RS07175	COG0706	membrane insertase activity
GFK26_RS07180	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GFK26_RS07185	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
GFK26_RS07185	COG2066	Belongs to the glutaminase family
GFK26_RS07205	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
GFK26_RS07215	COG0300	oxidoreductase activity
GFK26_RS07225	COG2119	membrane
GFK26_RS07230	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GFK26_RS07235	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GFK26_RS07235	COG2813	Specifically methylates the guanine in position
GFK26_RS07240	COG1739	Uncharacterized protein family UPF0029
GFK26_RS07245	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GFK26_RS07265	COG2267	carboxylic ester hydrolase activity
GFK26_RS07270	COG2814	Major facilitator Superfamily
GFK26_RS07285	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GFK26_RS07295	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GFK26_RS07300	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GFK26_RS07305	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GFK26_RS07320	COG0280	phosphate acetyltransferase
GFK26_RS07320	COG0281	malic enzyme
GFK26_RS07340	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GFK26_RS07385	COG0006	proline dipeptidase activity
GFK26_RS07395	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
GFK26_RS07400	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GFK26_RS07405	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GFK26_RS07440	COG3025	triphosphatase activity
GFK26_RS07450	COG1047	Peptidyl-prolyl cis-trans
GFK26_RS07470	COG1741	Belongs to the pirin family
GFK26_RS07475	COG1473	amidohydrolase
GFK26_RS07490	COG3938	Belongs to the proline racemase family
GFK26_RS07495	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GFK26_RS07510	COG1802	Transcriptional regulator
GFK26_RS07520	COG0697	spore germination
GFK26_RS07530	COG0513	Belongs to the DEAD box helicase family
GFK26_RS07535	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GFK26_RS07550	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GFK26_RS07555	COG1960	acyl-CoA dehydrogenase activity
GFK26_RS07575	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_RS07580	COG0583	DNA-binding transcription factor activity
GFK26_RS07600	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
GFK26_RS07600	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
GFK26_RS07615	COG0642	Histidine kinase
GFK26_RS07635	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GFK26_RS07640	COG2137	regulation of response to DNA damage stimulus
GFK26_RS07650	COG4682	membrane
GFK26_RS07660	COG3781	membrane
GFK26_RS07665	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GFK26_RS07670	COG0045	succinate-CoA ligase (ADP-forming) activity
GFK26_RS07675	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GFK26_RS07680	COG0861	Integral membrane protein TerC family
GFK26_RS07685	COG0631	protein serine/threonine phosphatase activity
GFK26_RS07690	COG1716	ATPase activity
GFK26_RS07705	COG4969	Belongs to the N-Me-Phe pilin family
GFK26_RS07710	COG3307	-O-antigen
GFK26_RS07760	COG0315	cyclic pyranopterin monophosphate synthase activity
GFK26_RS07765	COG4783	chaperone-mediated protein folding
GFK26_RS07770	COG1950	PFAM Membrane protein of
GFK26_RS07780	COG0861	Integral membrane protein TerC family
GFK26_RS07805	COG0625	glutathione transferase activity
GFK26_RS07820	COG1595	DNA-templated transcription, initiation
GFK26_RS07825	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GFK26_RS07835	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
GFK26_RS07855	COG4566	intracellular signal transduction
GFK26_RS07880	COG1522	sequence-specific DNA binding
GFK26_RS07890	COG2186	Transcriptional regulator
GFK26_RS07895	COG2271	Major facilitator Superfamily
GFK26_RS07900	COG2084	Dehydrogenase
GFK26_RS07905	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GFK26_RS07910	COG3395	kinase activity
GFK26_RS07915	COG0235	Class ii aldolase
GFK26_RS07920	COG3622	Belongs to the hyi family
GFK26_RS07930	COG0251	oxidation-reduction process
GFK26_RS07960	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GFK26_RS07975	COG2814	Major facilitator Superfamily
GFK26_RS07980	COG0765	amino acid transport
GFK26_RS07995	COG1522	sequence-specific DNA binding
GFK26_RS08005	COG1862	Preprotein translocase
GFK26_RS08010	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GFK26_RS08015	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GFK26_RS08025	COG2922	Belongs to the Smg family
GFK26_RS08030	COG0758	DNA mediated transformation
GFK26_RS08040	COG0242	peptide deformylase activity
GFK26_RS08050	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GFK26_RS08080	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GFK26_RS08100	COG0126	phosphoglycerate kinase activity
GFK26_RS08105	COG0469	pyruvate kinase activity
GFK26_RS08110	COG2515	1-aminocyclopropane-1-carboxylate deaminase
GFK26_RS08115	COG1522	sequence-specific DNA binding
GFK26_RS08130	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GFK26_RS08140	COG3550	peptidyl-serine autophosphorylation
GFK26_RS08145	COG3620	sequence-specific DNA binding
GFK26_RS08155	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GFK26_RS08160	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GFK26_RS08165	COG0009	L-threonylcarbamoyladenylate synthase
GFK26_RS08175	COG2027	D-alanyl-D-alanine carboxypeptidase
GFK26_RS08180	COG0494	nUDIX hydrolase
GFK26_RS08185	COG1349	DNA-binding transcription factor activity
GFK26_RS08195	COG1214	PFAM Peptidase M22, glycoprotease
GFK26_RS08210	COG0284	orotidine-5'-phosphate decarboxylase activity
GFK26_RS08255	COG0343	queuine tRNA-ribosyltransferase activity
GFK26_RS08260	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GFK26_RS08270	COG1090	epimerase
GFK26_RS08275	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GFK26_RS08280	COG1280	lysine exporter protein (LysE YggA)
GFK26_RS08300	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GFK26_RS08305	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GFK26_RS08310	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GFK26_RS08315	COG4770	biotin carboxylase activity
GFK26_RS08535	COG0783	Belongs to the Dps family
GFK26_RS08540	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GFK26_RS08560	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GFK26_RS08565	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GFK26_RS08570	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GFK26_RS08575	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GFK26_RS08580	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GFK26_RS08585	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GFK26_RS08590	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GFK26_RS08595	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GFK26_RS08600	COG1841	ribosomal large subunit assembly
GFK26_RS08605	COG0200	Binds to the 23S rRNA
GFK26_RS08610	COG0201	protein transport
GFK26_RS08615	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GFK26_RS08620	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GFK26_RS08625	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GFK26_RS08630	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GFK26_RS08635	COG0202	RNA polymerase activity
GFK26_RS08640	COG0203	ribosomal protein L17
GFK26_RS08660	COG1960	acyl-CoA dehydrogenase activity
GFK26_RS08665	COG1024	Enoyl-CoA hydratase
GFK26_RS08680	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GFK26_RS08695	COG0583	DNA-binding transcription factor activity
GFK26_RS08700	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_RS08710	COG0022	dehydrogenase e1 component
GFK26_RS08715	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GFK26_RS08725	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GFK26_RS08855	COG4213	ABC transporter substrate-binding protein
GFK26_RS08860	COG4214	carbohydrate transport
GFK26_RS08865	COG1129	ABC transporter
GFK26_RS08870	COG1940	carbohydrate kinase activity
GFK26_RS08875	COG4993	Dehydrogenase
GFK26_RS08925	COG0318	PFAM AMP-dependent synthetase and ligase
GFK26_RS08955	COG1022	Amp-dependent synthetase and ligase
GFK26_RS08960	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GFK26_RS08970	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_RS08995	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GFK26_RS09010	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GFK26_RS09040	COG4654	Cytochrome c, class I
GFK26_RS09045	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GFK26_RS09080	COG2391	methyltransferase activity
GFK26_RS09085	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GFK26_RS09110	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
GFK26_RS09115	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
GFK26_RS09120	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
GFK26_RS09130	COG2205	protein histidine kinase activity
GFK26_RS09135	COG0745	RESPONSE REGULATOR receiver
GFK26_RS09155	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GFK26_RS09160	COG1187	pseudouridine synthase activity
GFK26_RS09175	COG0642	Histidine kinase
GFK26_RS09185	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GFK26_RS09195	COG0583	DNA-binding transcription factor activity
GFK26_RS09200	COG1840	ABC-type Fe3 transport system, periplasmic component
GFK26_RS09205	COG0326	Molecular chaperone. Has ATPase activity
GFK26_RS09225	COG0714	Associated with various cellular activities
GFK26_RS09235	COG3552	Protein containing von Willebrand factor type A (VWA) domain
GFK26_RS09240	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GFK26_RS09250	COG1960	acyl-CoA dehydrogenase activity
GFK26_RS09255	COG0583	DNA-binding transcription factor activity
GFK26_RS09260	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GFK26_RS09270	COG1764	response to oxidative stress
GFK26_RS09275	COG1846	Transcriptional regulator
GFK26_RS09280	COG0842	Transport permease protein
GFK26_RS09285	COG1131	(ABC) transporter
GFK26_RS09295	COG0625	glutathione transferase activity
GFK26_RS09310	COG0640	Transcriptional regulator
GFK26_RS09325	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GFK26_RS09330	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GFK26_RS09340	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GFK26_RS09340	COG0574	Belongs to the PEP-utilizing enzyme family
GFK26_RS09350	COG0640	Transcriptional regulator
GFK26_RS09375	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GFK26_RS09390	COG2207	Transcriptional regulator
GFK26_RS09395	COG1652	LysM domain
GFK26_RS09400	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GFK26_RS09415	COG1250	3-hydroxyacyl-CoA dehydrogenase
GFK26_RS09420	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GFK26_RS09435	COG0559	Belongs to the binding-protein-dependent transport system permease family
GFK26_RS09455	COG1022	Amp-dependent synthetase and ligase
GFK26_RS09470	COG2095	MarC family integral membrane protein
GFK26_RS09475	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_RS09485	COG0412	Dienelactone hydrolase
GFK26_RS09490	COG0583	DNA-binding transcription factor activity
GFK26_RS09500	COG0598	Magnesium transport protein CorA
GFK26_RS09510	COG1981	membrane
GFK26_RS09525	COG2945	thiolester hydrolase activity
GFK26_RS09530	COG1686	Belongs to the peptidase S11 family
GFK26_RS09535	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GFK26_RS09540	COG0049	tRNA binding
GFK26_RS09545	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GFK26_RS09550	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GFK26_RS09555	COG0051	transcription antitermination factor activity, RNA binding
GFK26_RS09570	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GFK26_RS09575	COG0088	Forms part of the polypeptide exit tunnel
GFK26_RS09580	COG0089	rRNA binding
GFK26_RS09585	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GFK26_RS09590	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GFK26_RS09595	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GFK26_RS09600	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GFK26_RS09605	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GFK26_RS09610	COG0255	Belongs to the universal ribosomal protein uL29 family
GFK26_RS09615	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GFK26_RS09620	COG0678	peroxiredoxin activity
GFK26_RS09635	COG3909	cytochrome
GFK26_RS09640	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GFK26_RS09655	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GFK26_RS09660	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GFK26_RS09685	COG2205	protein histidine kinase activity
GFK26_RS09690	COG2130	NADP-dependent
GFK26_RS09710	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GFK26_RS09715	COG0318	PFAM AMP-dependent synthetase and ligase
GFK26_RS09730	COG2271	Major facilitator Superfamily
GFK26_RS09740	COG1012	belongs to the aldehyde dehydrogenase family
GFK26_RS09745	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GFK26_RS09760	COG0142	geranyltranstransferase activity
GFK26_RS09770	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GFK26_RS09790	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GFK26_RS09800	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GFK26_RS09805	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GFK26_RS09810	COG0321	lipoyl(octanoyl) transferase activity
GFK26_RS09815	COG2921	Belongs to the UPF0250 family
GFK26_RS09830	COG0356	it plays a direct role in the translocation of protons across the membrane
GFK26_RS09840	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GFK26_RS09845	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GFK26_RS09850	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GFK26_RS09855	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GFK26_RS09860	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GFK26_RS09865	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GFK26_RS09880	COG1172	Belongs to the binding-protein-dependent transport system permease family
GFK26_RS09885	COG1879	ABC-type sugar transport system periplasmic component
GFK26_RS09905	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
GFK26_RS09905	COG1793	dna ligase
GFK26_RS09910	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
GFK26_RS09910	COG1793	dna ligase
GFK26_RS09915	COG1201	RNA secondary structure unwinding
GFK26_RS09920	COG3118	belongs to the thioredoxin family
GFK26_RS09980	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GFK26_RS10005	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GFK26_RS10010	COG0792	nuclease activity
GFK26_RS10015	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GFK26_RS10025	COG2084	Dehydrogenase
GFK26_RS10055	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GFK26_RS10070	COG1505	serine-type exopeptidase activity
GFK26_RS10090	COG1309	transcriptional regulator
GFK26_RS10100	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GFK26_RS10100	COG2124	cytochrome p450
GFK26_RS10115	COG0318	PFAM AMP-dependent synthetase and ligase
GFK26_RS10120	COG0439	Biotin carboxylase
GFK26_RS10145	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GFK26_RS10180	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GFK26_RS10225	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GFK26_RS10230	COG0488	(ABC) transporter
GFK26_RS10265	COG0318	PFAM AMP-dependent synthetase and ligase
GFK26_RS10270	COG3186	Phenylalanine-4-hydroxylase
GFK26_RS10285	COG1522	sequence-specific DNA binding
GFK26_RS10300	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GFK26_RS10315	COG0671	phosphoesterase, PA-phosphatase related
GFK26_RS10325	COG1597	lipid kinase activity
GFK26_RS10330	COG0752	glycyl-tRNA synthetase alpha subunit
GFK26_RS10335	COG0751	glycine-tRNA ligase activity
GFK26_RS10340	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GFK26_RS10360	COG0564	pseudouridine synthase activity
GFK26_RS10375	COG0789	Transcriptional regulator
GFK26_RS10380	COG0288	reversible hydration of carbon dioxide
GFK26_RS10385	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
GFK26_RS10390	COG0183	Belongs to the thiolase family
GFK26_RS10400	COG1960	acyl-CoA dehydrogenase activity
GFK26_RS10405	COG1408	metallophosphoesterase
GFK26_RS10425	COG3012	SEC-C Motif Domain Protein
GFK26_RS10430	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GFK26_RS10435	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GFK26_RS10460	COG1960	acyl-CoA dehydrogenase activity
GFK26_RS10465	COG0318	PFAM AMP-dependent synthetase and ligase
GFK26_RS10470	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GFK26_RS10475	COG1024	Enoyl-CoA hydratase
GFK26_RS10500	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GFK26_RS10505	COG1414	Transcriptional regulator
GFK26_RS10520	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GFK26_RS10530	COG1254	Belongs to the acylphosphatase family
GFK26_RS10545	COG2815	serine threonine protein kinase
GFK26_RS10545	COG0515	serine threonine protein kinase
GFK26_RS10550	COG2116	formate transmembrane transporter activity
GFK26_RS10555	COG2146	nitrite reductase [NAD(P)H] activity
GFK26_RS10560	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GFK26_RS10580	COG0477	Major facilitator Superfamily
GFK26_RS10590	COG0683	leucine binding
GFK26_RS10595	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GFK26_RS10600	COG2423	ornithine cyclodeaminase activity
GFK26_RS10625	COG4555	ABC transporter
GFK26_RS10640	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GFK26_RS10650	COG3243	poly(R)-hydroxyalkanoic acid synthase
GFK26_RS10670	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
GFK26_RS10685	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GFK26_RS10690	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GFK26_RS10705	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GFK26_RS10710	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GFK26_RS10715	COG0316	Belongs to the HesB IscA family
GFK26_RS10720	COG2814	Major facilitator Superfamily
GFK26_RS10725	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
GFK26_RS10735	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GFK26_RS10750	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GFK26_RS10755	COG1490	D-aminoacyl-tRNA deacylase activity
GFK26_RS10765	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GFK26_RS10770	COG1702	phosphate starvation-inducible protein PhoH
GFK26_RS10775	COG0632	four-way junction helicase activity
GFK26_RS10790	COG1012	belongs to the aldehyde dehydrogenase family
GFK26_RS10855	COG4589	Belongs to the CDS family
GFK26_RS10870	COG2453	phosphatase
GFK26_RS10870	COG0671	phosphoesterase, PA-phosphatase related
GFK26_RS10875	COG2267	carboxylic ester hydrolase activity
GFK26_RS10880	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GFK26_RS10905	COG1960	acyl-CoA dehydrogenase activity
GFK26_RS10910	COG1960	acyl-CoA dehydrogenase activity
GFK26_RS10920	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GFK26_RS10925	COG0318	PFAM AMP-dependent synthetase and ligase
GFK26_RS10930	COG0318	PFAM AMP-dependent synthetase and ligase
GFK26_RS10945	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_RS10950	COG2909	trisaccharide binding
GFK26_RS10955	COG0183	Belongs to the thiolase family
GFK26_RS10960	COG1024	Enoyl-CoA hydratase
GFK26_RS10960	COG1250	3-hydroxyacyl-CoA dehydrogenase
GFK26_RS10990	COG0183	Belongs to the thiolase family
GFK26_RS11015	COG1024	Enoyl-CoA hydratase
GFK26_RS11145	COG0457	Tetratricopeptide repeat
GFK26_RS11200	COG0778	Nitroreductase
GFK26_RS11265	COG1024	Enoyl-CoA hydratase
GFK26_RS11285	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GFK26_RS11295	COG1869	D-ribose catabolic process
GFK26_RS11300	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GFK26_RS11305	COG1609	Transcriptional regulator
GFK26_RS11310	COG1172	Belongs to the binding-protein-dependent transport system permease family
GFK26_RS11315	COG1129	ABC transporter
GFK26_RS11320	COG1879	ABC-type sugar transport system periplasmic component
GFK26_RS11325	COG0012	GTP binding
GFK26_RS11340	COG1238	metal cluster binding
GFK26_RS11350	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
GFK26_RS11355	COG0138	bifunctional purine biosynthesis protein purh
GFK26_RS11365	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GFK26_RS11375	COG1773	rubredoxin
GFK26_RS11400	COG0784	Response regulator, receiver
GFK26_RS11400	COG2198	Histidine kinase
GFK26_RS11400	COG0643	Histidine kinase
GFK26_RS11405	COG0415	Belongs to the DNA photolyase family
GFK26_RS11410	COG1678	Uncharacterized ACR, COG1678
GFK26_RS11415	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GFK26_RS11420	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GFK26_RS11425	COG0540	Belongs to the ATCase OTCase family
GFK26_RS11430	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GFK26_RS11445	COG1053	succinate dehydrogenase
GFK26_RS11450	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_RS11480	COG0697	spore germination
GFK26_RS11485	COG1902	pentaerythritol trinitrate reductase activity
GFK26_RS11520	COG2205	protein histidine kinase activity
GFK26_RS11530	COG0745	RESPONSE REGULATOR receiver
GFK26_RS11565	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GFK26_RS11575	COG3485	protocatechuate 3,4-dioxygenase
GFK26_RS11580	COG3485	protocatechuate 3,4-dioxygenase
GFK26_RS11585	COG0583	DNA-binding transcription factor activity
GFK26_RS11600	COG2885	chlorophyll binding
GFK26_RS11605	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GFK26_RS11615	COG2274	protein secretion by the type I secretion system
GFK26_RS11620	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GFK26_RS11680	COG4964	Belongs to the GSP D family
GFK26_RS11705	COG3063	Type IV pilus biogenesis stability protein PilW
GFK26_RS11715	COG1414	Transcriptional regulator
GFK26_RS11725	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GFK26_RS11730	COG0183	Belongs to the thiolase family
GFK26_RS11735	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_RS11740	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_RS11755	COG0693	protein deglycase activity
GFK26_RS11760	COG0395	ABC-type sugar transport system, permease component
GFK26_RS11775	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_RS11785	COG1012	belongs to the aldehyde dehydrogenase family
GFK26_RS11795	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
GFK26_RS11820	COG0601	transmembrane transport
GFK26_RS11840	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GFK26_RS11845	COG0179	Fumarylacetoacetate (FAA) hydrolase
GFK26_RS11850	COG2003	Belongs to the UPF0758 family
GFK26_RS11860	COG4771	TonB-dependent receptor
GFK26_RS11880	COG4650	regulator
GFK26_RS11890	COG1690	Belongs to the RtcB family
GFK26_RS11900	COG0430	RNA-3'-phosphate cyclase activity
GFK26_RS11910	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
GFK26_RS11930	COG0154	amidase activity
GFK26_RS11935	COG2186	Transcriptional regulator
GFK26_RS11980	COG5507	3-demethylubiquinone-9 3-methyltransferase
GFK26_RS11995	COG2764	glyoxalase bleomycin resistance protein dioxygenase
GFK26_RS12010	COG1960	acyl-CoA dehydrogenase activity
GFK26_RS12030	COG1024	Enoyl-CoA hydratase
GFK26_RS12045	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_RS12065	COG0489	protein tyrosine kinase activity
GFK26_RS12080	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GFK26_RS12090	COG2226	methyltransferase
GFK26_RS12105	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GFK26_RS12110	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
GFK26_RS12145	COG0109	protoheme IX farnesyltransferase activity
GFK26_RS12150	COG1999	signal sequence binding
GFK26_RS12155	COG4335	DNA alkylation repair
GFK26_RS12180	COG2197	response regulator
GFK26_RS12195	COG0612	Peptidase, M16
GFK26_RS12200	COG0612	Peptidase, M16
GFK26_RS12215	COG0742	ribosomal rna small subunit methyltransferase
GFK26_RS12220	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GFK26_RS12225	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GFK26_RS12230	COG1984	allophanate hydrolase subunit 2
GFK26_RS12235	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GFK26_RS12240	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GFK26_RS12245	COG2267	carboxylic ester hydrolase activity
GFK26_RS12250	COG0588	phosphoglycerate mutase activity
GFK26_RS12255	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
GFK26_RS12285	COG0154	amidase activity
GFK26_RS12290	COG0747	negative chemotaxis
GFK26_RS12300	COG4608	Belongs to the ABC transporter superfamily
GFK26_RS12305	COG0444	Belongs to the ABC transporter superfamily
GFK26_RS12310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GFK26_RS12320	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GFK26_RS12335	COG0193	aminoacyl-tRNA hydrolase activity
GFK26_RS12340	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GFK26_RS12345	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GFK26_RS12355	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GFK26_RS12370	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GFK26_RS12375	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GFK26_RS12385	COG1660	Displays ATPase and GTPase activities
GFK26_RS12390	COG0497	DNA recombination
GFK26_RS12395	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GFK26_RS12400	COG1420	regulation of RNA biosynthetic process
GFK26_RS12425	COG1074	ATP-dependent DNA helicase activity
GFK26_RS12575	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GFK26_RS12585	COG0210	DNA helicase
GFK26_RS12630	COG0583	DNA-binding transcription factor activity
GFK26_RS12645	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GFK26_RS12675	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GFK26_RS12680	COG1758	RNA polymerase activity
GFK26_RS12685	COG0194	GDP metabolic process
GFK26_RS12690	COG1561	YicC-like family, N-terminal region
GFK26_RS12710	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GFK26_RS12715	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GFK26_RS12735	COG1129	ABC transporter
GFK26_RS12740	COG1172	Belongs to the binding-protein-dependent transport system permease family
GFK26_RS12745	COG1879	ABC-type sugar transport system periplasmic component
GFK26_RS12760	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GFK26_RS12765	COG2376	Dihydroxyacetone kinase
GFK26_RS12785	COG0596	Alpha beta hydrolase
GFK26_RS12785	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GFK26_RS12785	COG2226	methyltransferase
GFK26_RS12790	COG0318	PFAM AMP-dependent synthetase and ligase
GFK26_RS12810	COG4942	peptidase
GFK26_RS12810	COG1388	LysM domain
GFK26_RS12855	COG4944	Protein of unknown function (DUF1109)
GFK26_RS12860	COG1595	DNA-templated transcription, initiation
GFK26_RS12920	COG2199	diguanylate cyclase activity
GFK26_RS12920	COG2200	EAL domain
GFK26_RS12920	COG3287	FIST C domain
GFK26_RS12925	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GFK26_RS12950	COG4771	TonB-dependent receptor
GFK26_RS12955	COG2814	Major facilitator Superfamily
GFK26_RS12960	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GFK26_RS13010	COG2217	Heavy metal translocating P-type atpase
GFK26_RS13020	COG3278	Belongs to the heme-copper respiratory oxidase family
GFK26_RS13055	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GFK26_RS13070	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GFK26_RS13075	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GFK26_RS13115	COG1959	2 iron, 2 sulfur cluster binding
GFK26_RS13130	COG1335	isochorismatase
GFK26_RS13135	COG1335	isochorismatase
GFK26_RS13150	COG1283	sodium-dependent phosphate transmembrane transporter activity
GFK26_RS13155	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GFK26_RS13160	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GFK26_RS13180	COG1609	Transcriptional regulator
GFK26_RS13185	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GFK26_RS13195	COG0196	riboflavin kinase activity
GFK26_RS13205	COG1024	Enoyl-CoA hydratase
GFK26_RS13220	COG1960	acyl-CoA dehydrogenase activity
GFK26_RS13225	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GFK26_RS13245	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GFK26_RS13245	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GFK26_RS13260	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GFK26_RS13265	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GFK26_RS13270	COG0492	ferredoxin-NADP+ reductase activity
GFK26_RS13280	COG1674	ftsk spoiiie
GFK26_RS13285	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GFK26_RS13290	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GFK26_RS13295	COG0559	Belongs to the binding-protein-dependent transport system permease family
GFK26_RS13365	COG2816	NAD+ diphosphatase activity
GFK26_RS13370	COG0425	Belongs to the sulfur carrier protein TusA family
GFK26_RS13380	COG0525	valine-tRNA ligase activity
GFK26_RS13395	COG2267	carboxylic ester hydrolase activity
GFK26_RS13400	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GFK26_RS13400	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GFK26_RS13405	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_RS13420	COG4948	Mandelate Racemase Muconate Lactonizing
GFK26_RS13440	COG1960	acyl-CoA dehydrogenase activity
GFK26_RS13450	COG1960	acyl-CoA dehydrogenase activity
GFK26_RS13460	COG0318	PFAM AMP-dependent synthetase and ligase
GFK26_RS13490	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GFK26_RS13500	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
GFK26_RS13515	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_RS13520	COG0583	DNA-binding transcription factor activity
GFK26_RS13525	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
GFK26_RS13545	COG1598	PFAM Uncharacterised protein family UPF0150
GFK26_RS13550	COG1724	mRNA binding
GFK26_RS13565	COG0583	DNA-binding transcription factor activity
GFK26_RS13580	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
GFK26_RS13585	COG4221	oxidoreductase activity
GFK26_RS13610	COG2807	transmembrane transport
GFK26_RS13615	COG2186	Transcriptional regulator
GFK26_RS13620	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
GFK26_RS13625	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GFK26_RS13630	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GFK26_RS13650	COG1280	lysine exporter protein (LysE YggA)
GFK26_RS13735	COG4566	intracellular signal transduction
GFK26_RS13740	COG0477	Major facilitator Superfamily
GFK26_RS13750	COG0165	Argininosuccinate lyase
GFK26_RS13755	COG3275	phosphorelay sensor kinase activity
GFK26_RS13765	COG0628	permease
GFK26_RS13785	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GFK26_RS13800	COG0583	DNA-binding transcription factor activity
GFK26_RS13825	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GFK26_RS13830	COG0181	hydroxymethylbilane synthase activity
GFK26_RS13835	COG1587	Uroporphyrinogen-III synthase
GFK26_RS13855	COG0583	DNA-binding transcription factor activity
GFK26_RS13860	COG1530	ribonuclease E activity
GFK26_RS13880	COG0616	signal peptide processing
GFK26_RS13880	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GFK26_RS13885	COG2223	nitrite transmembrane transporter activity
GFK26_RS13895	COG0424	maF-like protein
GFK26_RS13900	COG1399	metal-binding, possibly nucleic acid-binding protein
GFK26_RS13905	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GFK26_RS13910	COG0416	fatty acid biosynthetic process
GFK26_RS13915	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GFK26_RS13920	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GFK26_RS13925	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_RS13930	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GFK26_RS13935	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GFK26_RS13960	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GFK26_RS13965	COG0481	GTPase activity
GFK26_RS13970	COG0681	Belongs to the peptidase S26 family
GFK26_RS13980	COG0571	ribonuclease III activity
GFK26_RS13985	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GFK26_RS13990	COG1381	Involved in DNA repair and RecF pathway recombination
GFK26_RS13995	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GFK26_RS14000	COG0736	holo-[acyl-carrier-protein] synthase activity
GFK26_RS14005	COG1472	Belongs to the glycosyl hydrolase 3 family
GFK26_RS14015	COG1451	nucleotide metabolic process
GFK26_RS14020	COG0443	Heat shock 70 kDa protein
GFK26_RS14035	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GFK26_RS14045	COG0762	integral membrane protein
GFK26_RS14050	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GFK26_RS14055	COG0159	tryptophan synthase activity
GFK26_RS14060	COG0133	tryptophan synthase activity
GFK26_RS14065	COG0135	phosphoribosylanthranilate isomerase activity
GFK26_RS14070	COG0101	tRNA pseudouridine synthase activity
GFK26_RS14080	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GFK26_RS14085	COG0473	3-isopropylmalate dehydrogenase activity
GFK26_RS14090	COG0066	3-isopropylmalate dehydratase activity
GFK26_RS14095	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GFK26_RS14105	COG0372	Belongs to the citrate synthase family
GFK26_RS14110	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
GFK26_RS14115	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GFK26_RS14120	COG1053	succinate dehydrogenase
GFK26_RS14135	COG2188	Transcriptional regulator
GFK26_RS14140	COG0039	L-malate dehydrogenase activity
GFK26_RS14145	COG4106	trans-aconitate 2-methyltransferase activity
GFK26_RS14180	COG3468	outer membrane autotransporter barrel domain protein
GFK26_RS14225	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GFK26_RS14235	COG0672	)-iron permease
GFK26_RS14240	COG2822	iron ion transport
GFK26_RS14250	COG2822	iron ion transport
GFK26_RS14260	COG1918	ferrous iron import across plasma membrane
GFK26_RS14260	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GFK26_RS14270	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GFK26_RS14285	COG3483	tryptophan 2,3-dioxygenase activity
GFK26_RS14295	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
GFK26_RS14300	COG1522	sequence-specific DNA binding
GFK26_RS14305	COG0727	PFAM Uncharacterised protein family (UPF0153)
GFK26_RS14315	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GFK26_RS14320	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GFK26_RS14330	COG0268	Binds directly to 16S ribosomal RNA
GFK26_RS14335	COG0728	peptidoglycan biosynthetic process
GFK26_RS14355	COG3795	YCII-related domain
GFK26_RS14365	COG4941	Belongs to the sigma-70 factor family
GFK26_RS14370	COG4977	sequence-specific DNA binding
GFK26_RS14370	COG1917	Cupin 2, conserved barrel domain protein
GFK26_RS14390	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GFK26_RS14395	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GFK26_RS14400	COG0617	tRNA 3'-terminal CCA addition
GFK26_RS14415	COG1392	Phosphate transport regulator
GFK26_RS14420	COG0306	phosphate transporter
GFK26_RS14435	COG0228	four-way junction DNA binding
GFK26_RS14440	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GFK26_RS14445	COG0336	Belongs to the RNA methyltransferase TrmD family
GFK26_RS14450	COG0335	large ribosomal subunit rRNA binding
GFK26_RS14455	COG0494	nUDIX hydrolase
GFK26_RS14460	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
GFK26_RS14465	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GFK26_RS14475	COG1162	GTPase activity
GFK26_RS14480	COG2154	pterin-4-alpha-carbinolamine dehydratase
GFK26_RS14490	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
GFK26_RS14495	COG0513	Belongs to the DEAD box helicase family
GFK26_RS14505	COG1250	3-hydroxyacyl-CoA dehydrogenase
GFK26_RS14510	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GFK26_RS14515	COG0604	alcohol dehydrogenase
GFK26_RS14565	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
GFK26_RS14575	COG0683	leucine binding
GFK26_RS14585	COG4638	Rieske (2fe-2S)
GFK26_RS14590	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
GFK26_RS14700	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
GFK26_RS14710	COG0308	aminopeptidase N
GFK26_RS14715	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GFK26_RS14730	COG1464	Belongs to the NlpA lipoprotein family
GFK26_RS14735	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GFK26_RS14740	COG2011	ABC-type metal ion transport system permease component
GFK26_RS14745	COG1464	Belongs to the NlpA lipoprotein family
GFK26_RS14760	COG1464	Belongs to the NlpA lipoprotein family
GFK26_RS14775	COG0667	Aldo Keto reductase
GFK26_RS14780	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GFK26_RS14785	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GFK26_RS14790	COG0251	oxidation-reduction process
GFK26_RS14800	COG1666	GTP binding
GFK26_RS14805	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GFK26_RS14815	COG0137	argininosuccinate synthase activity
GFK26_RS14820	COG3123	guanosine phosphorylase activity
GFK26_RS14830	COG1393	Belongs to the ArsC family
GFK26_RS14835	COG0285	dihydrofolate synthase activity
GFK26_RS14860	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GFK26_RS14920	COG1846	Transcriptional regulator
GFK26_RS14955	COG0683	leucine binding
GFK26_RS14975	COG0583	DNA-binding transcription factor activity
GFK26_RS15015	COG1283	sodium-dependent phosphate transmembrane transporter activity
GFK26_RS15040	COG1126	abc transporter atp-binding protein
GFK26_RS15045	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GFK26_RS15055	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GFK26_RS15065	COG0765	amino acid transport
GFK26_RS15120	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GFK26_RS15130	COG2301	Belongs to the HpcH HpaI aldolase family
GFK26_RS15135	COG2079	MmgE PrpD family protein
GFK26_RS15150	COG2030	dehydratase
GFK26_RS15155	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GFK26_RS15160	COG2301	Belongs to the HpcH HpaI aldolase family
GFK26_RS15165	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_RS15170	COG0045	succinate-CoA ligase (ADP-forming) activity
GFK26_RS15170	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GFK26_RS15170	COG1042	CoA-binding domain protein
GFK26_RS15185	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_RS15190	COG0183	Belongs to the thiolase family
GFK26_RS15195	COG1960	acyl-CoA dehydrogenase activity
GFK26_RS15200	COG0318	PFAM AMP-dependent synthetase and ligase
GFK26_RS15205	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_RS15210	COG1960	acyl-CoA dehydrogenase activity
GFK26_RS15235	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_RS15265	COG0583	DNA-binding transcription factor activity
GFK26_RS15280	COG0318	PFAM AMP-dependent synthetase and ligase
GFK26_RS15285	COG1960	acyl-CoA dehydrogenase activity
GFK26_RS15295	COG1024	Enoyl-CoA hydratase
GFK26_RS15305	COG1960	acyl-CoA dehydrogenase activity
GFK26_RS15310	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_RS15315	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_RS15325	COG1960	acyl-CoA dehydrogenase activity
GFK26_RS15330	COG0183	Belongs to the thiolase family
GFK26_RS15335	COG1960	acyl-CoA dehydrogenase activity
GFK26_RS15350	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GFK26_RS15355	COG0318	PFAM AMP-dependent synthetase and ligase
GFK26_RS15360	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_RS15365	COG0318	PFAM AMP-dependent synthetase and ligase
GFK26_RS15370	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_RS15390	COG1960	acyl-CoA dehydrogenase activity
GFK26_RS15395	COG2197	response regulator
GFK26_RS15405	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_RS15410	COG1024	Enoyl-CoA hydratase
GFK26_RS15415	COG1960	acyl-CoA dehydrogenase activity
GFK26_RS15420	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GFK26_RS15430	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GFK26_RS15475	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GFK26_RS15485	COG0583	DNA-binding transcription factor activity
GFK26_RS15510	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GFK26_RS15530	COG0582	viral genome integration into host DNA
GFK26_RS15540	COG2072	flavoprotein involved in K transport
GFK26_RS15550	COG2144	transferase activity, transferring acyl groups
GFK26_RS15560	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GFK26_RS15575	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GFK26_RS15590	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GFK26_RS15615	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_RS15640	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_RS15700	COG3251	PFAM MbtH domain protein
GFK26_RS15705	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
GFK26_RS15720	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GFK26_RS15730	COG4774	siderophore transport
GFK26_RS15735	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GFK26_RS15760	COG0625	glutathione transferase activity
GFK26_RS15780	COG0318	PFAM AMP-dependent synthetase and ligase
GFK26_RS15785	COG0318	PFAM AMP-dependent synthetase and ligase
GFK26_RS15800	COG0697	spore germination
GFK26_RS15810	COG2169	Transcriptional regulator
GFK26_RS15835	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GFK26_RS15840	COG1309	transcriptional regulator
GFK26_RS15845	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GFK26_RS15875	COG0259	pyridoxamine-phosphate oxidase activity
GFK26_RS15880	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GFK26_RS15905	COG1609	Transcriptional regulator
GFK26_RS15910	COG3265	gluconokinase activity
GFK26_RS15915	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GFK26_RS15920	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GFK26_RS15925	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GFK26_RS15935	COG0800	Aldolase
GFK26_RS15950	COG0346	lactoylglutathione lyase activity
GFK26_RS15960	COG3842	ATPase activity
GFK26_RS15970	COG1840	ABC-type Fe3 transport system, periplasmic component
GFK26_RS16000	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_RS16010	COG0235	Class ii aldolase
GFK26_RS16015	COG0800	Aldolase
GFK26_RS16020	COG3734	2-keto-3-deoxy-galactonokinase
GFK26_RS16025	COG0129	dihydroxy-acid dehydratase activity
GFK26_RS16030	COG2186	Transcriptional regulator
GFK26_RS16035	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GFK26_RS16040	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GFK26_RS16045	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GFK26_RS16065	COG0513	Belongs to the DEAD box helicase family
GFK26_RS16070	COG0488	(ABC) transporter
GFK26_RS16085	COG3191	aminopeptidase activity
GFK26_RS16110	COG2132	Multicopper oxidase
GFK26_RS16130	COG0584	glycerophosphoryl diester phosphodiesterase
GFK26_RS16150	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
GFK26_RS16155	COG0583	DNA-binding transcription factor activity
GFK26_RS16165	COG0765	amino acid transport
GFK26_RS16170	COG0765	amino acid transport
GFK26_RS16185	COG2271	Major facilitator Superfamily
GFK26_RS16210	COG1764	response to oxidative stress
GFK26_RS16220	COG0318	PFAM AMP-dependent synthetase and ligase
GFK26_RS16230	COG0300	oxidoreductase activity
GFK26_RS16235	COG1595	DNA-templated transcription, initiation
GFK26_RS16240	COG3712	iron ion homeostasis
GFK26_RS16245	COG4773	Receptor
GFK26_RS16280	COG3246	L-lysine catabolic process to acetate
GFK26_RS16290	COG3485	protocatechuate 3,4-dioxygenase
GFK26_RS16300	COG1525	nuclease
GFK26_RS16310	COG1252	NADH dehydrogenase
GFK26_RS16315	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GFK26_RS16320	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
GFK26_RS16330	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GFK26_RS16335	COG1172	Belongs to the binding-protein-dependent transport system permease family
GFK26_RS16340	COG1129	ABC transporter
GFK26_RS16345	COG1879	ABC-type sugar transport system periplasmic component
GFK26_RS16350	COG1984	allophanate hydrolase subunit 2
GFK26_RS16365	COG0511	ligase activity, forming carbon-carbon bonds
GFK26_RS16375	COG0583	DNA-binding transcription factor activity
GFK26_RS16390	COG0589	response to stress
GFK26_RS16395	COG0564	pseudouridine synthase activity
GFK26_RS16410	COG4628	conserved protein (DUF2132)
GFK26_RS16420	COG2354	Protein conserved in bacteria
GFK26_RS16460	COG4774	siderophore transport
GFK26_RS16495	COG0523	cobalamin synthesis protein
GFK26_RS16520	COG2918	glutathione biosynthetic process
GFK26_RS16525	COG2201	protein-glutamate methylesterase activity
GFK26_RS16530	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_RS16550	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GFK26_RS16560	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GFK26_RS16565	COG1131	(ABC) transporter
GFK26_RS16580	COG4774	siderophore transport
GFK26_RS16605	COG0004	ammonium transporteR
GFK26_RS16610	COG3177	Filamentation induced by cAMP protein fic
GFK26_RS16650	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GFK26_RS16665	COG3275	phosphorelay sensor kinase activity
GFK26_RS16725	COG1737	Transcriptional regulator
GFK26_RS16730	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GFK26_RS16735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GFK26_RS16750	COG1968	undecaprenyl-diphosphatase activity
GFK26_RS16770	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
GFK26_RS16775	COG4585	Histidine kinase
GFK26_RS16785	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_RS16790	COG3795	YCII-related domain
GFK26_RS16795	COG4941	Belongs to the sigma-70 factor family
GFK26_RS16815	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GFK26_RS16830	COG0598	Magnesium transport protein CorA
GFK26_RS16835	COG2375	cellular response to nickel ion
GFK26_RS16840	COG1695	Transcriptional regulator
GFK26_RS16845	COG0784	Response regulator, receiver
GFK26_RS16845	COG2205	protein histidine kinase activity
GFK26_RS16845	COG5002	protein histidine kinase activity
GFK26_RS16865	COG2274	protein secretion by the type I secretion system
GFK26_RS16885	COG2205	protein histidine kinase activity
GFK26_RS16885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GFK26_RS16915	COG3119	arylsulfatase activity
GFK26_RS16940	COG0583	DNA-binding transcription factor activity
GFK26_RS16950	COG2311	Membrane
GFK26_RS16970	COG1522	sequence-specific DNA binding
GFK26_RS16990	COG1289	transmembrane transporter activity
GFK26_RS16995	COG0483	inositol monophosphate 1-phosphatase activity
GFK26_RS17005	COG1045	serine acetyltransferase
GFK26_RS17010	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GFK26_RS17035	COG0789	Transcriptional regulator
GFK26_RS17060	COG0475	glutathione-regulated potassium exporter activity
GFK26_RS17120	COG0521	Mo-molybdopterin cofactor biosynthetic process
GFK26_RS17130	COG0312	modulator of DNA gyrase
GFK26_RS17140	COG1653	transport
GFK26_RS17150	COG0395	ABC-type sugar transport system, permease component
GFK26_RS17155	COG3842	ATPase activity
GFK26_RS17160	COG1063	alcohol dehydrogenase
GFK26_RS17165	COG0300	oxidoreductase activity
GFK26_RS17170	COG2072	flavoprotein involved in K transport
GFK26_RS17175	COG0385	Bile acid
GFK26_RS17180	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GFK26_RS17195	COG0494	nUDIX hydrolase
GFK26_RS17205	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GFK26_RS17210	COG2081	HI0933 family
GFK26_RS17215	COG0791	NLP P60 protein
GFK26_RS17230	COG3220	belongs to the UPF0276 family
GFK26_RS17260	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GFK26_RS17270	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GFK26_RS17275	COG0243	molybdopterin cofactor binding
GFK26_RS17285	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GFK26_RS17295	COG2223	nitrite transmembrane transporter activity
GFK26_RS17305	COG1116	anion transmembrane transporter activity
GFK26_RS17310	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GFK26_RS17315	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GFK26_RS17320	COG3707	response regulator
GFK26_RS17325	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GFK26_RS17340	COG0683	leucine binding
GFK26_RS17345	COG0436	Aminotransferase
GFK26_RS17360	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GFK26_RS17365	COG1185	polyribonucleotide nucleotidyltransferase activity
GFK26_RS17375	COG0149	triose-phosphate isomerase activity
GFK26_RS17390	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GFK26_RS17395	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GFK26_RS17400	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GFK26_RS17405	COG0649	NAD binding
GFK26_RS17420	COG1034	ATP synthesis coupled electron transport
GFK26_RS17425	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GFK26_RS17430	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GFK26_RS17440	COG0713	ATP synthesis coupled electron transport
GFK26_RS17455	COG1007	ATP synthesis coupled electron transport
GFK26_RS17465	COG0494	nUDIX hydrolase
GFK26_RS17475	COG1132	(ABC) transporter
GFK26_RS17480	COG1846	Transcriptional regulator
GFK26_RS17490	COG1566	PFAM secretion protein HlyD family protein
GFK26_RS17605	COG4941	Belongs to the sigma-70 factor family
GFK26_RS17610	COG3795	YCII-related domain
GFK26_RS17625	COG2186	Transcriptional regulator
GFK26_RS17635	COG4181	ATPase activity
GFK26_RS17640	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GFK26_RS17645	COG2207	Transcriptional regulator
GFK26_RS17675	COG0477	Major facilitator Superfamily
GFK26_RS17685	COG0129	dihydroxy-acid dehydratase activity
GFK26_RS17690	COG0179	Fumarylacetoacetate (FAA) hydrolase
GFK26_RS17695	COG2271	Major facilitator Superfamily
GFK26_RS17700	COG0583	DNA-binding transcription factor activity
GFK26_RS17710	COG0586	Pfam SNARE associated Golgi protein
GFK26_RS17720	COG0789	Transcriptional regulator
GFK26_RS17725	COG2226	methyltransferase
GFK26_RS17735	COG0860	N-Acetylmuramoyl-L-alanine amidase
GFK26_RS17740	COG0802	atpase or kinase
GFK26_RS17745	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GFK26_RS17760	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GFK26_RS17765	COG4774	siderophore transport
GFK26_RS17770	COG3214	Protein conserved in bacteria
GFK26_RS17785	COG0673	inositol 2-dehydrogenase activity
GFK26_RS17800	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GFK26_RS17805	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GFK26_RS17815	COG1309	transcriptional regulator
GFK26_RS17820	COG0028	Belongs to the TPP enzyme family
GFK26_RS17830	COG2207	Transcriptional regulator
GFK26_RS17860	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GFK26_RS17865	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GFK26_RS17870	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GFK26_RS17875	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GFK26_RS17880	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GFK26_RS17885	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GFK26_RS17885	COG0072	phenylalanine-tRNA ligase activity
GFK26_RS17890	COG0776	regulation of translation
GFK26_RS17960	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GFK26_RS17960	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GFK26_RS17965	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GFK26_RS18000	COG0419	ATPase involved in DNA repair
GFK26_RS18025	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GFK26_RS18165	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GFK26_RS18245	COG1690	Belongs to the RtcB family
GFK26_RS18365	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GFK26_RS18370	COG1475	DNA binding
GFK26_RS18495	COG3941	tape measure
GFK26_RS18575	COG1702	phosphate starvation-inducible protein PhoH
GFK26_RS18610	COG0358	DNA primase activity
GFK26_RS18645	COG0194	GDP metabolic process
GFK26_RS18665	COG0582	viral genome integration into host DNA
GFK26_RS18685	COG0583	DNA-binding transcription factor activity
GFK26_RS18705	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GFK26_RS18715	COG0183	Belongs to the thiolase family
GFK26_RS18730	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_RS18745	COG2003	Belongs to the UPF0758 family
GFK26_RS18755	COG1475	DNA binding
GFK26_RS18765	COG5489	Protein of unknown function (DUF736)
GFK26_RS18800	COG1192	Involved in chromosome partitioning
GFK26_RS18825	COG1104	cysteine desulfurase activity
GFK26_RS18855	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_RS18890	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GFK26_RS18925	COG2267	carboxylic ester hydrolase activity
GFK26_RS18930	COG2072	flavoprotein involved in K transport
GFK26_RS18935	COG2271	Major facilitator Superfamily
GFK26_RS18955	COG2368	4-hydroxyphenylacetate
GFK26_RS18975	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GFK26_RS19000	COG2315	Protein conserved in bacteria
GFK26_RS19010	COG0583	DNA-binding transcription factor activity
GFK26_RS19015	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_RS19040	COG1414	Transcriptional regulator
GFK26_RS19050	COG0183	Belongs to the thiolase family
GFK26_RS19055	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_RS19065	COG1960	acyl-CoA dehydrogenase activity
GFK26_RS19070	COG1024	Enoyl-CoA hydratase
GFK26_RS19075	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GFK26_RS19100	COG1024	Enoyl-CoA hydratase
GFK26_RS19110	COG0778	Nitroreductase
GFK26_RS19115	COG0667	Aldo Keto reductase
GFK26_RS19120	COG2272	Belongs to the type-B carboxylesterase lipase family
GFK26_RS19125	COG1024	Enoyl-CoA hydratase
GFK26_RS19155	COG2706	6-phosphogluconolactonase activity
GFK26_RS19160	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GFK26_RS19185	COG0583	DNA-binding transcription factor activity
GFK26_RS19200	COG4962	Type ii secretion system protein e
GFK26_RS19215	COG3451	type IV secretory pathway VirB4
GFK26_RS19230	COG3846	protein secretion by the type IV secretion system
GFK26_RS19255	COG1484	DNA-dependent DNA replication
GFK26_RS19260	COG4584	PFAM Integrase catalytic
GFK26_RS19285	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GFK26_RS19310	COG0789	Transcriptional regulator
GFK26_RS19320	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GFK26_RS19370	COG0582	viral genome integration into host DNA
GFK26_RS19400	COG1595	DNA-templated transcription, initiation
GFK26_RS19405	COG3712	iron ion homeostasis
GFK26_RS19415	COG0583	DNA-binding transcription factor activity
GFK26_RS19425	COG3693	PFAM glycoside hydrolase, family 10
GFK26_RS19475	COG0318	PFAM AMP-dependent synthetase and ligase
GFK26_RS19495	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_RS19505	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_RS19510	COG1609	Transcriptional regulator
GFK26_RS19525	COG0402	S-adenosylhomocysteine deaminase activity
GFK26_RS19530	COG0730	response to heat
GFK26_RS19560	COG1473	amidohydrolase
GFK26_RS19565	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_RS19570	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_RS19595	COG0583	DNA-binding transcription factor activity
GFK26_RS19600	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GFK26_RS19610	COG1960	acyl-CoA dehydrogenase activity
GFK26_RS19620	COG1024	Enoyl-CoA hydratase
GFK26_RS19640	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
GFK26_RS19645	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_RS19650	COG0583	DNA-binding transcription factor activity
GFK26_RS19655	COG2031	fatty acid transporter
GFK26_RS19665	COG2423	ornithine cyclodeaminase activity
GFK26_RS19670	COG0583	DNA-binding transcription factor activity
GFK26_RS19690	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GFK26_RS19725	COG0417	DNA replication proofreading
GFK26_RS19730	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GFK26_RS19745	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GFK26_RS19755	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
GFK26_RS19760	COG5002	protein histidine kinase activity
GFK26_RS19765	COG0392	lysyltransferase activity
GFK26_RS19790	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GFK26_RS19875	COG1522	sequence-specific DNA binding
GFK26_RS19895	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GFK26_RS19900	COG0006	proline dipeptidase activity
GFK26_RS19935	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GFK26_RS19945	COG2197	response regulator
GFK26_RS19965	COG1595	DNA-templated transcription, initiation
GFK26_RS19980	COG1960	acyl-CoA dehydrogenase activity
GFK26_RS19990	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GFK26_RS20005	COG4964	Belongs to the GSP D family
GFK26_RS20060	COG2197	response regulator
GFK26_RS20080	COG0778	Nitroreductase
GFK26_RS20150	COG1360	Flagellar Motor Protein
GFK26_RS20165	COG1742	UPF0060 membrane protein
GFK26_RS20175	COG1132	(ABC) transporter
GFK26_RS20180	COG3145	DNA-N1-methyladenine dioxygenase activity
GFK26_RS20215	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GFK26_RS20250	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GFK26_RS20260	COG3045	CreA protein
GFK26_RS20295	COG3243	poly(R)-hydroxyalkanoic acid synthase
GFK26_RS20300	COG0183	Belongs to the thiolase family
GFK26_RS20310	COG0583	DNA-binding transcription factor activity
GFK26_RS20315	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_RS20320	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
GFK26_RS20325	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GFK26_RS20345	COG1058	Belongs to the CinA family
GFK26_RS20345	COG1546	Belongs to the CinA family
GFK26_RS20355	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_RS20360	COG1301	dicarboxylic acid transport
GFK26_RS20365	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
GFK26_RS20370	COG4651	solute:proton antiporter activity
GFK26_RS20370	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GFK26_RS20385	COG4774	siderophore transport
GFK26_RS20430	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GFK26_RS20465	COG2076	Multidrug Resistance protein
GFK26_RS20480	COG2249	NAD(P)H dehydrogenase (quinone) activity
GFK26_RS20485	COG0583	DNA-binding transcription factor activity
GFK26_RS20520	COG3712	iron ion homeostasis
GFK26_RS20525	COG1595	DNA-templated transcription, initiation
GFK26_RS20560	COG3813	Protein conserved in bacteria
GFK26_RS20595	COG0028	Belongs to the TPP enzyme family
GFK26_RS20605	COG4172	Belongs to the ABC transporter superfamily
GFK26_RS20620	COG4166	transmembrane transport
GFK26_RS20630	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GFK26_RS20635	COG1802	Transcriptional regulator
GFK26_RS20735	COG2003	Belongs to the UPF0758 family
GFK26_RS20755	COG5489	Protein of unknown function (DUF736)
GFK26_RS20810	COG1192	Involved in chromosome partitioning
GFK26_RS20825	COG4959	Type IV secretory pathway protease TraF
GFK26_RS20835	COG0583	DNA-binding transcription factor activity
GFK26_RS20840	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GFK26_RS20850	COG0473	3-isopropylmalate dehydrogenase activity
GFK26_RS20890	COG1012	belongs to the aldehyde dehydrogenase family
GFK26_RS20940	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_RS21000	COG3246	L-lysine catabolic process to acetate
GFK26_RS21005	COG0179	Fumarylacetoacetate (FAA) hydrolase
GFK26_RS21020	COG1309	transcriptional regulator
GFK26_RS21055	COG0583	DNA-binding transcription factor activity
GFK26_RS21085	COG1414	Transcriptional regulator
GFK26_RS21090	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GFK26_RS21095	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GFK26_RS21120	COG0235	Class ii aldolase
GFK26_RS21125	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GFK26_RS21130	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GFK26_RS21170	COG1063	alcohol dehydrogenase
GFK26_RS21190	COG0179	Fumarylacetoacetate (FAA) hydrolase
GFK26_RS21215	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
GFK26_RS21230	COG1414	Transcriptional regulator
GFK26_RS21235	COG1024	Enoyl-CoA hydratase
GFK26_RS21245	COG1012	belongs to the aldehyde dehydrogenase family
GFK26_RS21250	COG1960	acyl-CoA dehydrogenase activity
GFK26_RS21255	COG1960	acyl-CoA dehydrogenase activity
GFK26_RS21260	COG1063	alcohol dehydrogenase
GFK26_RS21265	COG1414	Transcriptional regulator
GFK26_RS21270	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_RS21295	COG1137	ATPase activity
GFK26_RS21310	COG0596	Alpha beta hydrolase
GFK26_RS21320	COG3246	L-lysine catabolic process to acetate
GFK26_RS21335	COG1024	Enoyl-CoA hydratase
GFK26_RS21340	COG0318	PFAM AMP-dependent synthetase and ligase
GFK26_RS21345	COG2050	protein possibly involved in aromatic compounds catabolism
GFK26_RS21350	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GFK26_RS21355	COG1063	alcohol dehydrogenase
GFK26_RS21365	COG1960	acyl-CoA dehydrogenase activity
GFK26_RS21385	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_RS21400	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GFK26_RS21405	COG4948	Mandelate Racemase Muconate Lactonizing
GFK26_RS21410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GFK26_RS21420	COG0765	amino acid transport
GFK26_RS21485	COG0179	Fumarylacetoacetate (FAA) hydrolase
GFK26_RS21520	COG3246	L-lysine catabolic process to acetate
GFK26_RS21525	COG1250	3-hydroxyacyl-CoA dehydrogenase
GFK26_RS21530	COG1960	acyl-CoA dehydrogenase activity
GFK26_RS21535	COG1024	Enoyl-CoA hydratase
GFK26_RS21545	COG0318	PFAM AMP-dependent synthetase and ligase
GFK26_RS21555	COG1063	alcohol dehydrogenase
GFK26_RS21605	COG4372	Transposase
GFK26_RS21610	COG3436	PFAM IS66 Orf2 family protein
GFK26_RS21625	COG3618	amidohydrolase
GFK26_RS21630	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_RS21635	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GFK26_RS21665	COG0596	Alpha beta hydrolase
GFK26_RS21690	COG0583	DNA-binding transcription factor activity
GFK26_RS21705	COG4962	Type ii secretion system protein e
GFK26_RS21720	COG3451	type IV secretory pathway VirB4
GFK26_RS21750	COG2948	multi-organism process
GFK26_RS21790	COG2706	6-phosphogluconolactonase activity
GFK26_RS21795	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GFK26_RS21830	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GFK26_RS21840	COG1802	Transcriptional regulator
GFK26_RS21845	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GFK26_RS21845	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GFK26_RS21855	COG1703	isobutyryl-CoA mutase activity
GFK26_RS21860	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GFK26_RS21865	COG4770	biotin carboxylase activity
GFK26_RS21870	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GFK26_RS21880	COG1522	sequence-specific DNA binding
GFK26_RS21885	COG0697	spore germination
GFK26_RS21895	COG2878	Part of a membrane complex involved in electron transport
GFK26_RS21910	COG0556	nucleotide-excision repair
GFK26_RS21915	COG1959	2 iron, 2 sulfur cluster binding
GFK26_RS21920	COG1104	cysteine desulfurase activity
GFK26_RS21925	COG0822	iron-sulfur transferase activity
GFK26_RS21935	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GFK26_RS21940	COG0443	Heat shock 70 kDa protein
GFK26_RS21960	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
GFK26_RS21970	COG2197	response regulator
GFK26_RS21975	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GFK26_RS21980	COG0297	glycogen (starch) synthase activity
GFK26_RS22010	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GFK26_RS22015	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GFK26_RS22020	COG0489	protein tyrosine kinase activity
GFK26_RS22020	COG3206	protein involved in exopolysaccharide biosynthesis
GFK26_RS22025	COG1596	polysaccharide export
GFK26_RS22060	COG0579	oxidoreductase
GFK26_RS22075	COG0167	dihydroorotate dehydrogenase activity
GFK26_RS22080	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GFK26_RS22095	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GFK26_RS22100	COG4566	intracellular signal transduction
GFK26_RS22110	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GFK26_RS22115	COG0508	dehydrogenase complex catalyzes the overall conversion of
GFK26_RS22125	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GFK26_RS22130	COG0791	NLP P60 protein
GFK26_RS22135	COG2133	pyrroloquinoline quinone binding
GFK26_RS22145	COG2368	4-hydroxyphenylacetate
GFK26_RS22165	COG0567	Dehydrogenase, E1 component
GFK26_RS22170	COG0508	dehydrogenase complex catalyzes the overall conversion of
GFK26_RS22175	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GFK26_RS22180	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GFK26_RS22200	COG1199	ATP-dependent helicase activity
GFK26_RS22210	COG0564	pseudouridine synthase activity
GFK26_RS22215	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GFK26_RS22220	COG1187	pseudouridine synthase activity
GFK26_RS22225	COG0105	UTP biosynthetic process
GFK26_RS22230	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GFK26_RS22245	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GFK26_RS22250	COG0124	histidyl-tRNA synthetase
GFK26_RS22260	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GFK26_RS22265	COG1160	GTP binding
GFK26_RS22270	COG1923	regulation of RNA biosynthetic process
GFK26_RS22275	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GFK26_RS22280	COG0330	HflC and HflK could
GFK26_RS22285	COG0330	HflC and HflK could
GFK26_RS22295	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
GFK26_RS22300	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GFK26_RS22320	COG0501	Belongs to the peptidase M48B family
GFK26_RS22325	COG0626	cystathionine gamma-synthase activity
GFK26_RS22340	COG4181	ATPase activity
GFK26_RS22355	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GFK26_RS22360	COG0644	oxidoreductase
GFK26_RS22375	COG0667	Aldo Keto reductase
GFK26_RS22380	COG2059	Chromate
GFK26_RS22390	COG1295	ribonuclease BN
GFK26_RS22410	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_RS22450	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_RS22470	COG1024	Enoyl-CoA hydratase
GFK26_RS22515	COG0625	glutathione transferase activity
GFK26_RS22525	COG0492	ferredoxin-NADP+ reductase activity
GFK26_RS22535	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GFK26_RS22550	COG0248	Ppx GppA phosphatase
GFK26_RS22555	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GFK26_RS22560	COG0573	inorganic phosphate transmembrane transporter activity
GFK26_RS22565	COG0581	inorganic phosphate transmembrane transporter activity
GFK26_RS22570	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GFK26_RS22585	COG5002	protein histidine kinase activity
GFK26_RS22590	COG0534	Mate efflux family protein
GFK26_RS22600	COG0254	rRNA binding
GFK26_RS22605	COG0673	inositol 2-dehydrogenase activity
GFK26_RS22610	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GFK26_RS22625	COG1074	ATP-dependent DNA helicase activity
GFK26_RS22645	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GFK26_RS22650	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GFK26_RS22655	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GFK26_RS22665	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GFK26_RS22675	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GFK26_RS22680	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GFK26_RS22680	COG0475	glutathione-regulated potassium exporter activity
GFK26_RS22685	COG1388	LysM domain
GFK26_RS22685	COG0741	lytic transglycosylase activity
GFK26_RS22690	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GFK26_RS22700	COG0328	RNA-DNA hybrid ribonuclease activity
GFK26_RS22710	COG0746	molybdenum cofactor guanylyltransferase activity
GFK26_RS22715	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GFK26_RS22735	COG1012	belongs to the aldehyde dehydrogenase family
GFK26_RS22745	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GFK26_RS22805	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GFK26_RS22860	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GFK26_RS22885	COG0028	Belongs to the TPP enzyme family
GFK26_RS22890	COG0440	acetolactate synthase activity
GFK26_RS22895	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GFK26_RS22900	COG1183	phosphatidylcholine synthase activity
GFK26_RS22905	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GFK26_RS22910	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GFK26_RS22920	COG1414	Transcriptional regulator
GFK26_RS22925	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
GFK26_RS22930	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
GFK26_RS22940	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GFK26_RS22940	COG2207	Transcriptional regulator
GFK26_RS22960	COG1414	Transcriptional regulator
GFK26_RS22970	COG0642	Histidine kinase
GFK26_RS22975	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GFK26_RS22995	COG2267	carboxylic ester hydrolase activity
GFK26_RS23010	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GFK26_RS23015	COG0154	amidase activity
GFK26_RS23020	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_RS23095	COG2022	thiamine diphosphate biosynthetic process
GFK26_RS23110	COG0351	phosphomethylpyrimidine kinase
GFK26_RS23120	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
GFK26_RS23155	COG0492	ferredoxin-NADP+ reductase activity
GFK26_RS23160	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GFK26_RS23165	COG2895	sulfate adenylyltransferase (ATP) activity
GFK26_RS23165	COG0529	Catalyzes the synthesis of activated sulfate
GFK26_RS23190	COG0840	transmembrane signaling receptor activity
GFK26_RS23205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GFK26_RS23210	COG0601	transmembrane transport
GFK26_RS23215	COG0747	negative chemotaxis
GFK26_RS23220	COG4172	Belongs to the ABC transporter superfamily
GFK26_RS23225	COG1446	asparaginase
GFK26_RS23245	COG0789	Transcriptional regulator
GFK26_RS23265	COG0667	Aldo Keto reductase
GFK26_RS23270	COG0583	DNA-binding transcription factor activity
GFK26_RS23275	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GFK26_RS23285	COG0251	oxidation-reduction process
GFK26_RS23290	COG0583	DNA-binding transcription factor activity
GFK26_RS23295	COG0427	acetyl-CoA hydrolase
GFK26_RS23305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GFK26_RS23310	COG1879	ABC-type sugar transport system periplasmic component
GFK26_RS23315	COG1129	ABC transporter
GFK26_RS23325	COG1172	Belongs to the binding-protein-dependent transport system permease family
GFK26_RS23345	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GFK26_RS23355	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GFK26_RS23360	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
GFK26_RS23365	COG0745	RESPONSE REGULATOR receiver
GFK26_RS23370	COG5002	protein histidine kinase activity
GFK26_RS23390	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GFK26_RS23390	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
GFK26_RS23395	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
GFK26_RS23405	COG0431	NADPH-dependent FMN reductase
GFK26_RS23415	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GFK26_RS23420	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GFK26_RS23425	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GFK26_RS23430	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GFK26_RS23435	COG1116	anion transmembrane transporter activity
GFK26_RS23460	COG1045	serine acetyltransferase
GFK26_RS23470	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GFK26_RS23475	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GFK26_RS23490	COG3550	peptidyl-serine autophosphorylation
GFK26_RS23500	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GFK26_RS23520	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_RS23525	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GFK26_RS23535	COG0450	alkyl hydroperoxide reductase
GFK26_RS23545	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
GFK26_RS23555	COG4208	sulfate ABC transporter
GFK26_RS23560	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GFK26_RS23565	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GFK26_RS23570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GFK26_RS23580	COG1538	Outer membrane efflux protein
GFK26_RS23600	COG2226	methyltransferase
GFK26_RS23605	COG0217	transcriptional regulatory protein
GFK26_RS23610	COG0151	Belongs to the GarS family
GFK26_RS23615	COG0408	coproporphyrinogen oxidase activity
GFK26_RS23620	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GFK26_RS23625	COG0799	negative regulation of ribosome biogenesis
GFK26_RS23630	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GFK26_RS23635	COG0424	maF-like protein
GFK26_RS23640	COG1530	ribonuclease E activity
GFK26_RS23650	COG3246	L-lysine catabolic process to acetate
GFK26_RS23655	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_RS23660	COG1802	Transcriptional regulator
GFK26_RS23665	COG1132	(ABC) transporter
GFK26_RS23670	COG0823	Involved in the tonB-independent uptake of proteins
GFK26_RS23685	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GFK26_RS23695	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_RS23700	COG1024	Enoyl-CoA hydratase
GFK26_RS23725	COG1960	acyl-CoA dehydrogenase activity
GFK26_RS23740	COG2070	2-Nitropropane dioxygenase
GFK26_RS23745	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_RS23775	COG0488	(ABC) transporter
GFK26_RS23780	COG2890	protein-(glutamine-N5) methyltransferase activity
GFK26_RS23785	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GFK26_RS23795	COG2171	N-acyltransferase activity
GFK26_RS23810	COG1280	lysine exporter protein (LysE YggA)
GFK26_RS23815	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GFK26_RS23815	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GFK26_RS23820	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GFK26_RS23825	COG1643	Atp-dependent helicase
GFK26_RS23840	COG0436	Aminotransferase
GFK26_RS23845	COG0583	DNA-binding transcription factor activity
GFK26_RS23865	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GFK26_RS23900	COG0784	Response regulator, receiver
GFK26_RS23900	COG2205	protein histidine kinase activity
GFK26_RS23915	COG3121	Chaperone
GFK26_RS23950	COG0784	Response regulator, receiver
GFK26_RS23950	COG2205	protein histidine kinase activity
GFK26_RS23955	COG3204	pilus organization
GFK26_RS23980	COG1793	dna ligase
GFK26_RS23990	COG4166	transmembrane transport
GFK26_RS23995	COG4174	ABC transporter (Permease)
GFK26_RS24000	COG4239	(ABC) transporter, permease
GFK26_RS24005	COG4172	Belongs to the ABC transporter superfamily
GFK26_RS24010	COG0477	Major facilitator Superfamily
GFK26_RS24015	COG0779	Required for maturation of 30S ribosomal subunits
GFK26_RS24020	COG2251	uridine kinase activity
GFK26_RS24020	COG0195	Participates in both transcription termination and antitermination
GFK26_RS24025	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GFK26_RS24030	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GFK26_RS24035	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GFK26_RS24040	COG1217	gtp-binding protein TYPA
GFK26_RS24070	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GFK26_RS24075	COG2867	negative regulation of translational initiation
GFK26_RS24105	COG0519	Catalyzes the synthesis of GMP from XMP
GFK26_RS24105	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GFK26_RS24145	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_RS24165	COG0402	S-adenosylhomocysteine deaminase activity
GFK26_RS24175	COG1079	Belongs to the binding-protein-dependent transport system permease family
GFK26_RS24180	COG4603	Belongs to the binding-protein-dependent transport system permease family
GFK26_RS24185	COG3845	ABC transporter
GFK26_RS24195	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GFK26_RS24205	COG1744	ABC transporter substrate-binding protein PnrA-like
GFK26_RS24210	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GFK26_RS24235	COG1595	DNA-templated transcription, initiation
GFK26_RS24245	COG0433	COG0433 Predicted ATPase
GFK26_RS24260	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GFK26_RS24305	COG3550	peptidyl-serine autophosphorylation
GFK26_RS24320	COG1196	nuclear chromosome segregation
GFK26_RS24330	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GFK26_RS24340	COG0242	peptide deformylase activity
GFK26_RS24350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GFK26_RS24355	COG4597	amino acid ABC transporter
GFK26_RS24360	COG0765	amino acid transport
GFK26_RS24365	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GFK26_RS24380	COG2197	response regulator
GFK26_RS24390	COG0457	Tetratricopeptide repeat
GFK26_RS24395	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
GFK26_RS24400	COG1215	transferase activity, transferring glycosyl groups
GFK26_RS24405	COG1215	transferase activity, transferring glycosyl groups
GFK26_RS24410	COG2894	cell division
GFK26_RS24425	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
GFK26_RS24430	COG0024	Methionine aminopeptidase
GFK26_RS24435	COG0047	phosphoribosylformylglycinamidine synthase activity
GFK26_RS24435	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GFK26_RS24460	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GFK26_RS24470	COG2917	probably involved in intracellular septation
GFK26_RS24475	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GFK26_RS24480	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
GFK26_RS24490	COG2272	Belongs to the type-B carboxylesterase lipase family
GFK26_RS24495	COG0318	PFAM AMP-dependent synthetase and ligase
GFK26_RS24510	COG0559	Belongs to the binding-protein-dependent transport system permease family
GFK26_RS24520	COG0411	ABC transporter
GFK26_RS24530	COG1024	Enoyl-CoA hydratase
GFK26_RS24530	COG1250	3-hydroxyacyl-CoA dehydrogenase
GFK26_RS24535	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GFK26_RS24540	COG0183	Belongs to the thiolase family
GFK26_RS24550	COG1960	acyl-CoA dehydrogenase activity
GFK26_RS24580	COG2130	NADP-dependent
GFK26_RS24585	COG1960	acyl-CoA dehydrogenase activity
GFK26_RS24605	COG0583	DNA-binding transcription factor activity
GFK26_RS24610	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
GFK26_RS24630	COG2814	Major facilitator Superfamily
GFK26_RS24635	COG0583	DNA-binding transcription factor activity
GFK26_RS24655	COG1802	Transcriptional regulator
GFK26_RS24660	COG0277	FAD linked oxidase domain protein
GFK26_RS24660	COG0247	lactate metabolic process
GFK26_RS24695	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GFK26_RS24705	COG0583	DNA-binding transcription factor activity
GFK26_RS24720	COG2814	Major facilitator Superfamily
GFK26_RS24725	COG2814	Major facilitator Superfamily
GFK26_RS24730	COG2995	paraquat-inducible protein a
GFK26_RS24735	COG2995	paraquat-inducible protein a
GFK26_RS24740	COG3008	intermembrane lipid transfer
GFK26_RS24740	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GFK26_RS24750	COG0477	Major facilitator Superfamily
GFK26_RS24765	COG1595	DNA-templated transcription, initiation
GFK26_RS24770	COG3712	iron ion homeostasis
GFK26_RS24775	COG4774	siderophore transport
GFK26_RS24785	COG0534	Mate efflux family protein
GFK26_RS24825	COG2201	protein-glutamate methylesterase activity
GFK26_RS24830	COG4585	Histidine kinase
GFK26_RS24835	COG2183	response to ionizing radiation
GFK26_RS24910	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GFK26_RS24915	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GFK26_RS24930	COG0084	hydrolase, TatD family'
GFK26_RS24935	COG0666	response to abiotic stimulus
GFK26_RS24965	COG2197	response regulator
GFK26_RS24970	COG2197	response regulator
GFK26_RS24975	COG0251	oxidation-reduction process
GFK26_RS24985	COG0590	tRNA wobble adenosine to inosine editing
GFK26_RS24990	COG2351	hydroxyisourate hydrolase activity
GFK26_RS25010	COG0583	DNA-binding transcription factor activity
GFK26_RS25020	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_RS25025	COG1473	amidohydrolase
GFK26_RS25030	COG2207	Transcriptional regulator
GFK26_RS25055	COG1042	CoA-binding domain protein
GFK26_RS25055	COG0045	succinate-CoA ligase (ADP-forming) activity
GFK26_RS25055	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GFK26_RS25070	COG3360	Dodecin
GFK26_RS25075	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GFK26_RS25080	COG0154	amidase activity
GFK26_RS25090	COG2207	Transcriptional regulator
GFK26_RS25095	COG0667	Aldo Keto reductase
GFK26_RS25100	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GFK26_RS25105	COG0156	8-amino-7-oxononanoate synthase activity
GFK26_RS25165	COG5002	protein histidine kinase activity
GFK26_RS25165	COG0784	Response regulator, receiver
GFK26_RS25170	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GFK26_RS25180	COG5002	protein histidine kinase activity
GFK26_RS25210	COG1619	proteins homologs of microcin C7 resistance protein MccF
GFK26_RS25225	COG2808	Putative FMN-binding domain
GFK26_RS25240	COG4566	intracellular signal transduction
GFK26_RS25245	COG4191	Histidine kinase
GFK26_RS25270	COG2925	Exonuclease
GFK26_RS25275	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GFK26_RS25280	COG0542	response to heat
GFK26_RS25285	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GFK26_RS25320	COG2885	chlorophyll binding
GFK26_RS25320	COG3047	cAMP biosynthetic process
GFK26_RS25390	COG0811	peptide transport
GFK26_RS25395	COG0848	biopolymer transport protein
GFK26_RS25400	COG1663	tetraacyldisaccharide 4'-kinase activity
GFK26_RS25405	COG2835	tetraacyldisaccharide 4'-kinase activity
GFK26_RS25410	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
GFK26_RS25415	COG0563	adenylate kinase activity
GFK26_RS25420	COG0252	asparaginase activity
GFK26_RS25425	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GFK26_RS25435	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GFK26_RS25445	COG1250	3-hydroxyacyl-CoA dehydrogenase
GFK26_RS25450	COG1024	Enoyl-CoA hydratase
GFK26_RS25455	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GFK26_RS25475	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GFK26_RS25485	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GFK26_RS25490	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
GFK26_RS25495	COG1534	Rna-binding protein
GFK26_RS25510	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GFK26_RS25520	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GFK26_RS25525	COG0505	Belongs to the CarA family
GFK26_RS25530	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GFK26_RS25535	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GFK26_RS25540	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GFK26_RS25545	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GFK26_RS25550	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GFK26_RS25555	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GFK26_RS25565	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GFK26_RS25570	COG0750	zinc metalloprotease
GFK26_RS25575	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GFK26_RS25580	COG0575	Belongs to the CDS family
GFK26_RS25585	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GFK26_RS25590	COG0233	cytoplasmic translational termination
GFK26_RS25595	COG0528	UMP kinase activity
GFK26_RS25600	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GFK26_RS25605	COG0052	Belongs to the universal ribosomal protein uS2 family
GFK26_RS25625	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GFK26_RS25625	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GFK26_RS25630	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_RS25635	COG0557	exoribonuclease II activity
GFK26_RS25650	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GFK26_RS25655	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
GFK26_RS25670	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GFK26_RS25705	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GFK26_RS25705	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GFK26_RS25710	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GFK26_RS25710	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GFK26_RS25715	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GFK26_RS25720	COG0560	Phosphoserine phosphatase
GFK26_RS25740	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GFK26_RS25745	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GFK26_RS25760	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
GFK26_RS25765	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
GFK26_RS25770	COG1492	cobalamin metabolic process
GFK26_RS25780	COG1538	Outer membrane efflux protein
GFK26_RS25790	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GFK26_RS25810	COG1346	cytolysis
GFK26_RS25825	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
GFK26_RS25845	COG0778	Nitroreductase
GFK26_RS25850	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
GFK26_RS25860	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GFK26_RS25865	COG4607	ABC-type enterochelin transport system periplasmic component
GFK26_RS25875	COG1797	cobyrinic acid a,c-diamide synthase activity
GFK26_RS25895	COG0730	response to heat
GFK26_RS25910	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GFK26_RS25915	COG0318	PFAM AMP-dependent synthetase and ligase
GFK26_RS25935	COG1802	Transcriptional regulator
GFK26_RS25940	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GFK26_RS25955	COG0583	DNA-binding transcription factor activity
GFK26_RS25960	COG0583	DNA-binding transcription factor activity
GFK26_RS25965	COG0129	dihydroxy-acid dehydratase activity
GFK26_RS25980	COG4654	Cytochrome c, class I
GFK26_RS25990	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GFK26_RS26000	COG0583	DNA-binding transcription factor activity
GFK26_RS26005	COG2910	NAD(P)H-binding
GFK26_RS26010	COG0114	fumarate hydratase activity
GFK26_RS26015	COG4175	Glycine betaine
GFK26_RS26020	COG4176	ABC-type proline glycine betaine transport system permease component
GFK26_RS26025	COG2113	Glycine betaine
GFK26_RS26070	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GFK26_RS26075	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GFK26_RS26080	COG0740	serine-type endopeptidase activity
GFK26_RS26085	COG0544	peptidyl-prolyl cis-trans isomerase activity
GFK26_RS26100	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GFK26_RS26105	COG3158	transport of potassium into the cell
GFK26_RS26115	COG1562	ergosterol biosynthetic process
GFK26_RS26120	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
GFK26_RS26130	COG1280	lysine exporter protein (LysE YggA)
GFK26_RS26140	COG1011	Hydrolase
GFK26_RS26145	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GFK26_RS26150	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GFK26_RS26240	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_RS26250	COG0642	Histidine kinase
GFK26_RS26260	COG2326	polyphosphate kinase activity
GFK26_RS26280	COG2207	Transcriptional regulator
GFK26_RS26315	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GFK26_RS26370	COG0527	aspartate kinase activity
GFK26_RS26375	COG0037	tRNA processing
GFK26_RS26380	COG0825	malonyl-CoA metabolic process
GFK26_RS26390	COG0215	cysteine-tRNA ligase activity
GFK26_RS26405	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GFK26_RS26410	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GFK26_RS26435	COG0741	lytic transglycosylase activity
GFK26_RS26440	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GFK26_RS26445	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GFK26_RS26450	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GFK26_RS26450	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GFK26_RS26465	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GFK26_RS26470	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GFK26_RS26475	COG0436	Aminotransferase
GFK26_RS26480	COG0824	Thioesterase
GFK26_RS26490	COG0848	biopolymer transport protein
GFK26_RS26505	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
GFK26_RS26505	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
GFK26_RS26520	COG1054	Belongs to the UPF0176 family
GFK26_RS26525	COG1741	Belongs to the pirin family
GFK26_RS26535	COG2259	Doxx family
GFK26_RS26540	COG1741	Belongs to the pirin family
GFK26_RS26550	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
GFK26_RS26550	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GFK26_RS26555	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GFK26_RS26560	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GFK26_RS26590	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GFK26_RS26595	COG0477	Major facilitator Superfamily
GFK26_RS26605	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GFK26_RS26630	COG3976	FMN-binding domain protein
GFK26_RS26630	COG0431	NADPH-dependent FMN reductase
GFK26_RS26630	COG1053	succinate dehydrogenase
GFK26_RS26665	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
GFK26_RS26675	COG0647	UMP catabolic process
GFK26_RS26680	COG1737	Transcriptional regulator
GFK26_RS26690	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GFK26_RS26695	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GFK26_RS26730	COG3842	ATPase activity
GFK26_RS26750	COG2205	protein histidine kinase activity
GFK26_RS26750	COG0784	Response regulator, receiver
GFK26_RS26750	COG2198	Histidine kinase
GFK26_RS26770	COG0583	DNA-binding transcription factor activity
GFK26_RS26790	COG0604	alcohol dehydrogenase
GFK26_RS26795	COG1309	transcriptional regulator
GFK26_RS26815	COG2271	Major facilitator Superfamily
GFK26_RS26840	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GFK26_RS26855	COG1012	belongs to the aldehyde dehydrogenase family
GFK26_RS26860	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
GFK26_RS26865	COG0028	Belongs to the TPP enzyme family
GFK26_RS26870	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_RS26875	COG1414	Transcriptional regulator
GFK26_RS26895	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_RS26900	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GFK26_RS26910	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GFK26_RS26930	COG1640	4-alpha-glucanotransferase
GFK26_RS26935	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GFK26_RS26950	COG0366	Alpha amylase catalytic
GFK26_RS26955	COG0366	Alpha amylase catalytic
GFK26_RS26960	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GFK26_RS27005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GFK26_RS27065	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_RS27075	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_RS27100	COG2201	protein-glutamate methylesterase activity
GFK26_RS27110	COG2204	response regulator
GFK26_RS27120	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GFK26_RS27135	COG0071	Belongs to the small heat shock protein (HSP20) family
GFK26_RS27150	COG2080	2 iron, 2 sulfur cluster binding
GFK26_RS27155	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
GFK26_RS27160	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GFK26_RS27170	COG5492	domain, Protein
GFK26_RS27170	COG4932	domain protein
GFK26_RS27205	COG3196	Protein conserved in bacteria
GFK26_RS27240	COG0789	Transcriptional regulator
GFK26_RS27260	COG2175	clavaminate synthase activity
GFK26_RS27265	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GFK26_RS27285	COG0730	response to heat
GFK26_RS27290	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GFK26_RS27295	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
GFK26_RS27300	COG4521	taurine ABC transporter
GFK26_RS27305	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GFK26_RS27340	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GFK26_RS27345	COG1113	amino acid transport
GFK26_RS27360	COG2855	membrane
GFK26_RS27365	COG0583	DNA-binding transcription factor activity
GFK26_RS27370	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GFK26_RS27445	COG2890	protein-(glutamine-N5) methyltransferase activity
GFK26_RS27470	COG4221	oxidoreductase activity
GFK26_RS27475	COG0318	PFAM AMP-dependent synthetase and ligase
GFK26_RS27535	COG1335	isochorismatase
GFK26_RS27555	COG0583	DNA-binding transcription factor activity
GFK26_RS27585	COG0587	DNA-directed DNA polymerase activity
GFK26_RS27615	COG3384	dioxygenase
GFK26_RS27620	COG0583	DNA-binding transcription factor activity
GFK26_RS27625	COG1132	(ABC) transporter
GFK26_RS27660	COG1160	GTP binding
GFK26_RS27665	COG1024	Enoyl-CoA hydratase
GFK26_RS27675	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GFK26_RS27680	COG1272	protein, Hemolysin III
GFK26_RS27690	COG1960	acyl-CoA dehydrogenase activity
GFK26_RS27695	COG0318	PFAM AMP-dependent synthetase and ligase
GFK26_RS27700	COG0583	DNA-binding transcription factor activity
GFK26_RS27710	COG0640	Transcriptional regulator
GFK26_RS27730	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_RS27735	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GFK26_RS27740	COG0583	DNA-binding transcription factor activity
GFK26_RS27745	COG0519	Catalyzes the synthesis of GMP from XMP
GFK26_RS27745	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GFK26_RS27750	COG1183	phosphatidylcholine synthase activity
GFK26_RS27780	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GFK26_RS27785	COG2818	Glycosylase
GFK26_RS27800	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GFK26_RS27805	COG0583	DNA-binding transcription factor activity
GFK26_RS27820	COG1024	Enoyl-CoA hydratase
GFK26_RS27850	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GFK26_RS27870	COG0456	acetyltransferase
GFK26_RS27875	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_RS27885	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GFK26_RS27890	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GFK26_RS27950	COG1012	belongs to the aldehyde dehydrogenase family
GFK26_RS27955	COG3284	Transcriptional regulator
GFK26_RS27985	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GFK26_RS27995	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
GFK26_RS28005	COG0545	Peptidyl-prolyl cis-trans isomerase
GFK26_RS28010	COG0531	amino acid
GFK26_RS28015	COG4303	Ethanolamine ammonia lyase large subunit
GFK26_RS28020	COG4302	ethanolamine ammonia-lyase activity
GFK26_RS28040	COG2194	sulfuric ester hydrolase activity
GFK26_RS28045	COG0671	phosphoesterase, PA-phosphatase related
GFK26_RS28055	COG0745	RESPONSE REGULATOR receiver
GFK26_RS28060	COG0642	Histidine kinase
GFK26_RS28065	COG0824	Thioesterase
GFK26_RS28075	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_RS28090	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GFK26_RS28095	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GFK26_RS28105	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GFK26_RS28105	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GFK26_RS28135	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GFK26_RS28140	COG0509	glycine decarboxylation via glycine cleavage system
GFK26_RS28145	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GFK26_RS28145	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GFK26_RS28170	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GFK26_RS28220	COG1473	amidohydrolase
GFK26_RS28245	COG3148	PFAM DTW domain containing protein
GFK26_RS28265	COG0477	Major facilitator Superfamily
GFK26_RS28270	COG1082	Xylose isomerase domain protein TIM barrel
GFK26_RS28270	COG3185	4-Hydroxyphenylpyruvate dioxygenase
GFK26_RS28280	COG2814	Major facilitator Superfamily
GFK26_RS28290	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GFK26_RS28295	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GFK26_RS28300	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GFK26_RS28305	COG1414	Transcriptional regulator
GFK26_RS28340	COG0745	RESPONSE REGULATOR receiver
GFK26_RS28345	COG0642	Histidine kinase
GFK26_RS28365	COG0024	Methionine aminopeptidase
GFK26_RS28415	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GFK26_RS28425	COG0477	Major facilitator Superfamily
GFK26_RS28430	COG3795	YCII-related domain
GFK26_RS28435	COG3795	YCII-related domain
GFK26_RS28450	COG0640	Transcriptional regulator
GFK26_RS28460	COG1024	Enoyl-CoA hydratase
GFK26_RS28465	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_RS28475	COG2030	dehydratase
GFK26_RS28485	COG0318	PFAM AMP-dependent synthetase and ligase
GFK26_RS28505	COG1294	oxidase, subunit
GFK26_RS28510	COG1271	oxidase subunit
GFK26_RS28515	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GFK26_RS28520	COG4988	ABC transporter
GFK26_RS28535	COG1960	acyl-CoA dehydrogenase activity
GFK26_RS28550	COG1196	nuclear chromosome segregation
GFK26_RS28550	COG3264	Mechanosensitive ion channel
GFK26_RS28560	COG0714	Associated with various cellular activities
GFK26_RS28575	COG2951	lytic endotransglycosylase activity
GFK26_RS28605	COG1131	(ABC) transporter
GFK26_RS28620	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GFK26_RS28640	COG0395	ABC-type sugar transport system, permease component
GFK26_RS28650	COG3842	ATPase activity
GFK26_RS28655	COG3842	ATPase activity
GFK26_RS28670	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GFK26_RS28685	COG2308	Evidence 4 Homologs of previously reported genes of
GFK26_RS28725	COG4585	Histidine kinase
GFK26_RS28730	COG2197	response regulator
GFK26_RS28755	COG2271	Major facilitator Superfamily
GFK26_RS28775	COG0583	DNA-binding transcription factor activity
GFK26_RS28785	COG1024	Enoyl-CoA hydratase
GFK26_RS28790	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GFK26_RS28800	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GFK26_RS28815	COG5002	protein histidine kinase activity
GFK26_RS28820	COG2197	response regulator
GFK26_RS28830	COG1609	Transcriptional regulator
GFK26_RS28840	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GFK26_RS28850	COG1126	abc transporter atp-binding protein
GFK26_RS28855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GFK26_RS28860	COG0765	amino acid transport
GFK26_RS28865	COG0765	amino acid transport
GFK26_RS28905	COG0741	lytic transglycosylase activity
GFK26_RS28915	COG0583	DNA-binding transcription factor activity
GFK26_RS28925	COG2814	Major facilitator Superfamily
GFK26_RS28930	COG2814	Major facilitator Superfamily
GFK26_RS28940	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GFK26_RS28945	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
GFK26_RS28950	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GFK26_RS28965	COG2850	peptidyl-arginine hydroxylation
GFK26_RS28970	COG1047	Peptidyl-prolyl cis-trans
GFK26_RS28980	COG0756	dUTP diphosphatase activity
GFK26_RS28990	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GFK26_RS28995	COG0504	CTP synthase activity
GFK26_RS29000	COG2877	3-deoxy-8-phosphooctulonate synthase activity
GFK26_RS29010	COG0148	phosphopyruvate hydratase activity
GFK26_RS29015	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
GFK26_RS29020	COG3201	nicotinamide mononucleotide transporter
GFK26_RS29040	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_RS29050	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GFK26_RS29060	COG2833	Protein of unknown function (DUF455)
GFK26_RS29075	COG0183	Belongs to the thiolase family
GFK26_RS29080	COG1309	transcriptional regulator
GFK26_RS29085	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_RS29105	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
GFK26_RS29110	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
GFK26_RS29115	COG0583	DNA-binding transcription factor activity
GFK26_RS29120	COG4974	Belongs to the 'phage' integrase family
GFK26_RS29125	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_RS29140	COG0789	Transcriptional regulator
GFK26_RS29150	COG2814	Major facilitator Superfamily
GFK26_RS29165	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GFK26_RS29185	COG0583	DNA-binding transcription factor activity
GFK26_RS29210	COG0183	Belongs to the thiolase family
GFK26_RS29215	COG1024	Enoyl-CoA hydratase
GFK26_RS29220	COG1309	transcriptional regulator
GFK26_RS29250	COG1022	Amp-dependent synthetase and ligase
GFK26_RS29260	COG0542	response to heat
GFK26_RS29265	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_RS29275	COG0314	molybdopterin synthase activity
GFK26_RS29280	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GFK26_RS29290	COG0303	'Molybdopterin
GFK26_RS29295	COG1763	Mo-molybdopterin cofactor biosynthetic process
GFK26_RS29300	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GFK26_RS29315	COG0436	Aminotransferase
GFK26_RS29325	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GFK26_RS29360	COG0305	Participates in initiation and elongation during chromosome replication
GFK26_RS29365	COG0359	binds to the 23S rRNA
GFK26_RS29370	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GFK26_RS29375	COG2965	DNA replication, synthesis of RNA primer
GFK26_RS29380	COG0360	Binds together with S18 to 16S ribosomal RNA
GFK26_RS29395	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GFK26_RS29400	COG3634	alkyl hydroperoxide reductase activity
GFK26_RS29435	COG1477	protein flavinylation
GFK26_RS29440	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GFK26_RS29445	COG4774	siderophore transport
GFK26_RS29450	COG3128	pkhd-type hydroxylase
GFK26_RS29480	COG3193	protein, possibly involved in utilization of glycolate and propanediol
GFK26_RS29485	COG0670	Belongs to the BI1 family
GFK26_RS29490	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GFK26_RS29505	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GFK26_RS29510	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GFK26_RS29545	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GFK26_RS29560	COG0473	3-isopropylmalate dehydrogenase activity
GFK26_RS29565	COG0596	Alpha beta hydrolase
GFK26_RS29570	COG0583	DNA-binding transcription factor activity
GFK26_RS29580	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GFK26_RS29585	COG0322	excinuclease ABC activity
GFK26_RS29590	COG0405	Gamma-glutamyltransferase
GFK26_RS29605	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GFK26_RS29610	COG1611	Belongs to the LOG family
GFK26_RS29615	COG1309	transcriptional regulator
GFK26_RS29625	COG0477	Major facilitator Superfamily
GFK26_RS29640	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GFK26_RS29650	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GFK26_RS29655	COG3237	CsbD-like
GFK26_RS29670	COG0123	including yeast histone deacetylase and acetoin utilization protein
GFK26_RS29685	COG1959	2 iron, 2 sulfur cluster binding
GFK26_RS29685	COG1295	ribonuclease BN
GFK26_RS29700	COG2814	Major facilitator Superfamily
GFK26_RS29715	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GFK26_RS29720	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GFK26_RS29725	COG0583	DNA-binding transcription factor activity
GFK26_RS29775	COG1802	Transcriptional regulator
GFK26_RS29785	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GFK26_RS29795	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GFK26_RS29810	COG1012	belongs to the aldehyde dehydrogenase family
GFK26_RS29825	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_RS29835	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GFK26_RS29840	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_RS29845	COG2186	Transcriptional regulator
GFK26_RS29850	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GFK26_RS29860	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GFK26_RS29870	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GFK26_RS29870	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GFK26_RS29875	COG2721	sulfolactate sulfo-lyase activity
GFK26_RS29895	COG0688	phosphatidylethanolamine metabolic process
GFK26_RS29910	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GFK26_RS29915	COG0443	Heat shock 70 kDa protein
GFK26_RS29920	COG0484	heat shock protein binding
GFK26_RS29925	COG2766	serine protein kinase
GFK26_RS29930	COG2718	Belongs to the UPF0229 family
GFK26_RS29935	COG2719	SpoVR family
GFK26_RS29940	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GFK26_RS29960	COG0625	glutathione transferase activity
GFK26_RS29975	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
GFK26_RS29985	COG0346	lactoylglutathione lyase activity
GFK26_RS29990	COG3070	regulator of competence-specific genes
GFK26_RS30005	COG0640	Transcriptional regulator
GFK26_RS30020	COG0431	NADPH-dependent FMN reductase
GFK26_RS30065	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_RS30075	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GFK26_RS30140	COG4638	Rieske (2fe-2S)
GFK26_RS30145	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_RS30150	COG1414	Transcriptional regulator
GFK26_RS30170	COG0583	DNA-binding transcription factor activity
GFK26_RS30175	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GFK26_RS30195	COG2267	carboxylic ester hydrolase activity
GFK26_RS30205	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GFK26_RS30215	COG1295	ribonuclease BN
GFK26_RS30225	COG0277	FAD linked oxidase domain protein
GFK26_RS30245	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GFK26_RS30265	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GFK26_RS30270	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GFK26_RS30285	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GFK26_RS30290	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GFK26_RS30295	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GFK26_RS30300	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GFK26_RS30315	COG0535	radical SAM domain protein
GFK26_RS30325	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
GFK26_RS30330	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GFK26_RS30350	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GFK26_RS30370	COG3485	protocatechuate 3,4-dioxygenase
GFK26_RS30410	COG1012	belongs to the aldehyde dehydrogenase family
GFK26_RS30450	COG1764	response to oxidative stress
GFK26_RS30460	COG0596	Alpha beta hydrolase
GFK26_RS30495	COG0243	molybdopterin cofactor binding
GFK26_RS30495	COG3383	formate dehydrogenase (NAD+) activity
GFK26_RS30500	COG0437	4 iron, 4 sulfur cluster binding
GFK26_RS30525	COG0303	'Molybdopterin
GFK26_RS30540	COG0708	Exodeoxyribonuclease III
GFK26_RS30555	COG3852	Histidine kinase
GFK26_RS30565	COG0174	glutamine synthetase
GFK26_RS30570	COG1058	Belongs to the CinA family
GFK26_RS30570	COG1546	Belongs to the CinA family
GFK26_RS30605	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GFK26_RS30605	COG4797	methyltransferase
GFK26_RS30615	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
GFK26_RS30665	COG2010	Cytochrome c
GFK26_RS30665	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GFK26_RS30670	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GFK26_RS30675	COG1573	uracil-dna glycosylase
GFK26_RS30680	COG2323	membrane
GFK26_RS30685	COG0028	Belongs to the TPP enzyme family
GFK26_RS30710	COG2267	carboxylic ester hydrolase activity
GFK26_RS30745	COG0517	IMP dehydrogenase activity
GFK26_RS30760	COG0768	penicillin binding
GFK26_RS30785	COG2271	Major facilitator Superfamily
GFK26_RS30790	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GFK26_RS30805	COG0154	amidase activity
GFK26_RS30840	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GFK26_RS30865	COG1595	DNA-templated transcription, initiation
GFK26_RS30880	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GFK26_RS30885	COG1595	DNA-templated transcription, initiation
GFK26_RS30900	COG5001	Diguanylate cyclase
GFK26_RS30915	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GFK26_RS30935	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GFK26_RS30940	COG1605	Chorismate mutase
GFK26_RS30940	COG0077	Prephenate dehydratase
GFK26_RS30945	COG0287	Prephenate dehydrogenase
GFK26_RS30950	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GFK26_RS30970	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
GFK26_RS30980	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GFK26_RS30990	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GFK26_RS30990	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GFK26_RS30995	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GFK26_RS31000	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GFK26_RS31000	COG2111	Na H antiporter
GFK26_RS31005	COG1006	Multisubunit Na H antiporter MnhC subunit
GFK26_RS31010	COG0651	ATP synthesis coupled electron transport
GFK26_RS31020	COG2212	antiporter activity
GFK26_RS31025	COG1320	monovalent cation:proton antiporter activity
GFK26_RS31035	COG1309	transcriptional regulator
GFK26_RS31040	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GFK26_RS31065	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GFK26_RS31065	COG3608	succinylglutamate desuccinylase aspartoacylase
GFK26_RS31135	COG0559	Belongs to the binding-protein-dependent transport system permease family
GFK26_RS31145	COG2188	Transcriptional regulator
GFK26_RS31170	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GFK26_RS31180	COG1012	belongs to the aldehyde dehydrogenase family
GFK26_RS31190	COG1802	Transcriptional regulator
GFK26_RS31195	COG1840	ABC-type Fe3 transport system, periplasmic component
GFK26_RS31200	COG3842	ATPase activity
GFK26_RS31230	COG0477	Major facilitator Superfamily
GFK26_RS31235	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GFK26_RS31245	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GFK26_RS31250	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GFK26_RS31255	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GFK26_RS31260	COG0142	geranyltranstransferase activity
GFK26_RS31265	COG1722	exodeoxyribonuclease VII activity
GFK26_RS31305	COG3064	Membrane
GFK26_RS31365	COG0747	negative chemotaxis
GFK26_RS31370	COG0601	transmembrane transport
GFK26_RS31375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GFK26_RS31380	COG0444	Belongs to the ABC transporter superfamily
GFK26_RS31385	COG4608	Belongs to the ABC transporter superfamily
GFK26_RS31390	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
GFK26_RS31400	COG0747	negative chemotaxis
GFK26_RS31405	COG0601	transmembrane transport
GFK26_RS31410	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GFK26_RS31415	COG4172	Belongs to the ABC transporter superfamily
GFK26_RS31435	COG0412	Dienelactone hydrolase
GFK26_RS31460	COG4774	siderophore transport
GFK26_RS31490	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GFK26_RS31500	COG0210	DNA helicase
GFK26_RS31505	COG3047	cAMP biosynthetic process
GFK26_RS31510	COG0516	GMP reductase activity
GFK26_RS31580	COG0583	DNA-binding transcription factor activity
GFK26_RS31585	COG4948	Mandelate Racemase Muconate Lactonizing
GFK26_RS31600	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GFK26_RS31610	COG1192	Involved in chromosome partitioning
GFK26_RS31625	COG0583	DNA-binding transcription factor activity
GFK26_RS31660	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GFK26_RS31665	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GFK26_RS31675	COG1253	flavin adenine dinucleotide binding
GFK26_RS31680	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GFK26_RS31695	COG2197	response regulator
GFK26_RS31715	COG1116	anion transmembrane transporter activity
GFK26_RS31720	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GFK26_RS31725	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GFK26_RS31735	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GFK26_RS31745	COG1960	acyl-CoA dehydrogenase activity
GFK26_RS31750	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GFK26_RS31765	COG0513	Belongs to the DEAD box helicase family
GFK26_RS31770	COG2321	neutral zinc metallopeptidase
GFK26_RS31775	COG0717	Belongs to the dCTP deaminase family
GFK26_RS31780	COG0402	S-adenosylhomocysteine deaminase activity
GFK26_RS31790	COG2366	antibiotic biosynthetic process
GFK26_RS31795	COG4977	sequence-specific DNA binding
GFK26_RS31800	COG0583	DNA-binding transcription factor activity
GFK26_RS31805	COG2814	Major facilitator Superfamily
GFK26_RS31810	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GFK26_RS31815	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GFK26_RS31850	COG3845	ABC transporter
GFK26_RS31855	COG2252	PERMEase
GFK26_RS31865	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GFK26_RS31875	COG0730	response to heat
GFK26_RS31895	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_RS31955	COG2351	hydroxyisourate hydrolase activity
GFK26_RS31960	COG2186	Transcriptional regulator
GFK26_RS31975	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GFK26_RS31995	COG4774	siderophore transport
GFK26_RS32010	COG1953	Uracil, thiamine, allantoin
GFK26_RS32025	COG1309	transcriptional regulator
GFK26_RS32040	COG2233	PERMEase
GFK26_RS32045	COG0656	L-ascorbic acid biosynthetic process
GFK26_RS32050	COG0473	3-isopropylmalate dehydrogenase activity
GFK26_RS32060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GFK26_RS32065	COG0444	Belongs to the ABC transporter superfamily
GFK26_RS32070	COG4608	Belongs to the ABC transporter superfamily
GFK26_RS32080	COG0154	amidase activity
GFK26_RS32130	COG2085	NADP oxidoreductase coenzyme F420-dependent
GFK26_RS32140	COG0583	DNA-binding transcription factor activity
GFK26_RS32155	COG1301	dicarboxylic acid transport
GFK26_RS32165	COG0628	permease
GFK26_RS32180	COG0583	DNA-binding transcription factor activity
GFK26_RS32185	COG3960	tartronate-semialdehyde synthase activity
GFK26_RS32190	COG3622	Belongs to the hyi family
GFK26_RS32195	COG2084	Dehydrogenase
GFK26_RS32205	COG0280	phosphate acetyltransferase
GFK26_RS32205	COG0281	malic enzyme
GFK26_RS32210	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GFK26_RS32225	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GFK26_RS32235	COG1116	anion transmembrane transporter activity
GFK26_RS32240	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GFK26_RS32280	COG0642	Histidine kinase
GFK26_RS32295	COG1733	regulation of RNA biosynthetic process
GFK26_RS32310	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GFK26_RS32320	COG3135	benzoate transporter
GFK26_RS32335	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GFK26_RS32345	COG0829	nickel cation binding
GFK26_RS32365	COG2855	membrane
GFK26_RS32375	COG2879	small protein
GFK26_RS32380	COG1966	Carbon starvation protein
GFK26_RS32430	COG0791	NLP P60 protein
GFK26_RS32465	COG0667	Aldo Keto reductase
GFK26_RS32470	COG2814	Major facilitator Superfamily
GFK26_RS32530	COG0613	PHP domain protein
GFK26_RS32540	COG0009	L-threonylcarbamoyladenylate synthase
GFK26_RS32545	COG1994	Peptidase M50
GFK26_RS32550	COG0180	Tryptophanyl-tRNA synthetase
GFK26_RS32555	COG2197	response regulator
GFK26_RS32560	COG2205	protein histidine kinase activity
GFK26_RS32560	COG2198	Histidine kinase
GFK26_RS32560	COG0784	Response regulator, receiver
GFK26_RS32565	COG1950	PFAM Membrane protein of
GFK26_RS32570	COG1473	amidohydrolase
GFK26_RS32575	COG0583	DNA-binding transcription factor activity
GFK26_RS32580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GFK26_RS32585	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GFK26_RS32655	COG1191	sigma factor activity
GFK26_RS32670	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GFK26_RS32695	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
GFK26_RS32700	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GFK26_RS32705	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GFK26_RS32710	COG2198	Histidine kinase
GFK26_RS32710	COG0643	Histidine kinase
GFK26_RS32735	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GFK26_RS32755	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GFK26_RS32760	COG1334	flagellar protein FlaG
GFK26_RS32770	COG1677	Flagellar hook-basal body complex protein FliE
GFK26_RS32805	COG1580	Controls the rotational direction of flagella during chemotaxis
GFK26_RS32815	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GFK26_RS32830	COG1987	bacterial-type flagellum assembly
GFK26_RS32850	COG2877	3-deoxy-8-phosphooctulonate synthase activity
GFK26_RS32900	COG1256	bacterial-type flagellum assembly
GFK26_RS32910	COG0835	chemotaxis
GFK26_RS32915	COG0840	transmembrane signaling receptor activity
GFK26_RS32935	COG0840	transmembrane signaling receptor activity
GFK26_RS32940	COG1705	Flagellar rod assembly protein muramidase FlgJ
GFK26_RS32940	COG3951	Flagellar rod assembly protein muramidase FlgJ
GFK26_RS32945	COG1706	bacterial-type flagellum-dependent cell motility
GFK26_RS32950	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
GFK26_RS32975	COG1558	bacterial-type flagellum-dependent cell motility
GFK26_RS32980	COG1815	bacterial-type flagellum-dependent cell motility
GFK26_RS33010	COG0583	DNA-binding transcription factor activity
GFK26_RS33020	COG0583	DNA-binding transcription factor activity
GFK26_RS33030	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_RS33040	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GFK26_RS33050	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GFK26_RS33055	COG1047	Peptidyl-prolyl cis-trans
GFK26_RS33060	COG2003	Belongs to the UPF0758 family
GFK26_RS33070	COG0737	Belongs to the 5'-nucleotidase family
GFK26_RS33085	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GFK26_RS33095	COG0765	amino acid transport
GFK26_RS33100	COG0765	amino acid transport
GFK26_RS33115	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GFK26_RS33120	COG0477	Major facilitator Superfamily
GFK26_RS33125	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GFK26_RS33130	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GFK26_RS33135	COG1845	cytochrome c oxidase, subunit III
GFK26_RS33140	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GFK26_RS33155	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
GFK26_RS33160	COG1272	protein, Hemolysin III
GFK26_RS33165	COG2900	Belongs to the SlyX family
GFK26_RS33170	COG0477	Major facilitator Superfamily
GFK26_RS33175	COG0583	DNA-binding transcription factor activity
GFK26_RS33190	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
GFK26_RS33195	COG0709	Synthesizes selenophosphate from selenide and ATP
GFK26_RS33200	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
GFK26_RS33205	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
GFK26_RS33210	COG3639	organic phosphonate transmembrane transporter activity
GFK26_RS33220	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
GFK26_RS33225	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GFK26_RS33235	COG0243	molybdopterin cofactor binding
GFK26_RS33245	COG0725	ABC transporter, periplasmic molybdate-binding protein
GFK26_RS33250	COG4149	molybdate abc transporter
GFK26_RS33260	COG0583	DNA-binding transcription factor activity
GFK26_RS33265	COG0489	protein tyrosine kinase activity
GFK26_RS33280	COG1473	amidohydrolase
GFK26_RS33285	COG1522	sequence-specific DNA binding
GFK26_RS33295	COG3132	Protein of unknown function, DUF480
GFK26_RS33305	COG0473	3-isopropylmalate dehydrogenase activity
GFK26_RS33310	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GFK26_RS33310	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GFK26_RS33330	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GFK26_RS33340	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GFK26_RS33340	COG1024	Enoyl-CoA hydratase
GFK26_RS33345	COG0659	secondary active sulfate transmembrane transporter activity
GFK26_RS33365	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GFK26_RS33370	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GFK26_RS33375	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GFK26_RS33380	COG0602	queuosine metabolic process
GFK26_RS33385	COG0720	synthase
GFK26_RS33390	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GFK26_RS33400	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GFK26_RS33405	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
GFK26_RS33415	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GFK26_RS33420	COG0588	phosphoglycerate mutase activity
GFK26_RS33425	COG0793	Belongs to the peptidase S41A family
GFK26_RS33430	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GFK26_RS33435	COG2982	Protein involved in outer membrane biogenesis
GFK26_RS33445	COG2197	response regulator
GFK26_RS33455	COG5487	UPF0391 membrane protein
GFK26_RS33475	COG2823	Periplasmic or secreted lipoprotein
GFK26_RS33505	COG0494	nUDIX hydrolase
GFK26_RS33520	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GFK26_RS33540	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GFK26_RS33555	COG2226	methyltransferase
GFK26_RS33580	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GFK26_RS33590	COG1175	transmembrane transport
GFK26_RS33595	COG0395	ABC-type sugar transport system, permease component
GFK26_RS33600	COG3842	ATPase activity
GFK26_RS33605	COG0584	glycerophosphoryl diester phosphodiesterase
GFK26_RS33610	COG3264	Mechanosensitive ion channel
GFK26_RS33610	COG1511	domain protein
GFK26_RS33615	COG1522	sequence-specific DNA binding
GFK26_RS33625	COG4120	Belongs to the binding-protein-dependent transport system permease family
GFK26_RS33630	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
GFK26_RS33645	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GFK26_RS33650	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GFK26_RS33655	COG2890	protein-(glutamine-N5) methyltransferase activity
GFK26_RS33660	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GFK26_RS33665	COG1253	flavin adenine dinucleotide binding
GFK26_RS33670	COG0741	lytic transglycosylase activity
GFK26_RS33675	COG0442	prolyl-tRNA aminoacylation
GFK26_RS33680	COG0494	nUDIX hydrolase
GFK26_RS33690	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GFK26_RS33695	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GFK26_RS33700	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GFK26_RS33705	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GFK26_RS33710	COG0142	geranyltranstransferase activity
GFK26_RS33730	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GFK26_RS33750	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
GFK26_RS33755	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
GFK26_RS33770	COG0494	nUDIX hydrolase
GFK26_RS33780	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GFK26_RS33785	COG0653	protein targeting
GFK26_RS33815	COG0831	urea catabolic process
GFK26_RS33830	COG0804	urea catabolic process
GFK26_RS33865	COG0583	DNA-binding transcription factor activity
GFK26_RS33875	COG0583	DNA-binding transcription factor activity
GFK26_RS33895	COG1028	Short-chain dehydrogenase reductase Sdr