locus-tag	class	description
H7F35_RS00020	COG0713	ATP synthesis coupled electron transport
H7F35_RS00030	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H7F35_RS00035	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
H7F35_RS00040	COG1034	ATP synthesis coupled electron transport
H7F35_RS00055	COG0649	NAD binding
H7F35_RS00060	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H7F35_RS00065	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H7F35_RS00070	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H7F35_RS00085	COG0149	triose-phosphate isomerase activity
H7F35_RS00095	COG1185	polyribonucleotide nucleotidyltransferase activity
H7F35_RS00100	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
H7F35_RS00105	COG0697	spore germination
H7F35_RS00110	COG0436	Aminotransferase
H7F35_RS00115	COG0683	leucine binding
H7F35_RS00130	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
H7F35_RS00135	COG3707	response regulator
H7F35_RS00140	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H7F35_RS00145	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H7F35_RS00150	COG1116	anion transmembrane transporter activity
H7F35_RS00160	COG2223	nitrite transmembrane transporter activity
H7F35_RS00165	COG2815	serine threonine protein kinase
H7F35_RS00165	COG0515	serine threonine protein kinase
H7F35_RS00170	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H7F35_RS00180	COG2146	nitrite reductase [NAD(P)H] activity
H7F35_RS00185	COG0243	molybdopterin cofactor binding
H7F35_RS00190	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H7F35_RS00210	COG0791	NLP P60 protein
H7F35_RS00215	COG2081	HI0933 family
H7F35_RS00220	COG0828	Belongs to the bacterial ribosomal protein bS21 family
H7F35_RS00225	COG1610	YqeY-like protein
H7F35_RS00230	COG0494	nUDIX hydrolase
H7F35_RS00250	COG0385	Bile acid
H7F35_RS00255	COG2072	flavoprotein involved in K transport
H7F35_RS00265	COG1063	alcohol dehydrogenase
H7F35_RS00270	COG3842	ATPase activity
H7F35_RS00275	COG0395	ABC-type sugar transport system, permease component
H7F35_RS00285	COG1653	transport
H7F35_RS00295	COG0312	modulator of DNA gyrase
H7F35_RS00305	COG0521	Mo-molybdopterin cofactor biosynthetic process
H7F35_RS00350	COG0475	glutathione-regulated potassium exporter activity
H7F35_RS00380	COG0789	Transcriptional regulator
H7F35_RS00385	COG1045	serine acetyltransferase
H7F35_RS00395	COG0483	inositol monophosphate 1-phosphatase activity
H7F35_RS00400	COG1289	transmembrane transporter activity
H7F35_RS00410	COG1473	amidohydrolase
H7F35_RS00420	COG1574	metal-dependent hydrolase with the TIM-barrel fold
H7F35_RS00425	COG1522	sequence-specific DNA binding
H7F35_RS00445	COG2311	Membrane
H7F35_RS00485	COG3119	arylsulfatase activity
H7F35_RS00510	COG1858	cytochrome C peroxidase
H7F35_RS00525	COG1846	Transcriptional regulator
H7F35_RS00540	COG2375	cellular response to nickel ion
H7F35_RS00555	COG0598	Magnesium transport protein CorA
H7F35_RS00565	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
H7F35_RS00585	COG3795	YCII-related domain
H7F35_RS00590	COG0454	-acetyltransferase
H7F35_RS00590	COG0456	acetyltransferase
H7F35_RS00595	COG2197	response regulator
H7F35_RS00600	COG4585	Histidine kinase
H7F35_RS00620	COG1968	undecaprenyl-diphosphatase activity
H7F35_RS00635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7F35_RS00640	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
H7F35_RS00645	COG1737	Transcriptional regulator
H7F35_RS00650	COG1802	Transcriptional regulator
H7F35_RS00670	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H7F35_RS00675	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H7F35_RS00700	COG2972	Histidine kinase
H7F35_RS00715	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H7F35_RS00755	COG0004	ammonium transporteR
H7F35_RS00805	COG4774	siderophore transport
H7F35_RS00820	COG1131	(ABC) transporter
H7F35_RS00825	COG0257	Belongs to the bacterial ribosomal protein bL36 family
H7F35_RS00850	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
H7F35_RS00860	COG0517	IMP dehydrogenase activity
H7F35_RS00860	COG0617	tRNA 3'-terminal CCA addition
H7F35_RS00860	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
H7F35_RS00870	COG2267	carboxylic ester hydrolase activity
H7F35_RS00875	COG0789	Transcriptional regulator
H7F35_RS00885	COG1028	Short-chain dehydrogenase reductase Sdr
H7F35_RS00895	COG2918	glutathione biosynthetic process
H7F35_RS00905	COG0400	carboxylic ester hydrolase activity
H7F35_RS00915	COG3181	Tripartite tricarboxylate transporter family receptor
H7F35_RS00920	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H7F35_RS00925	COG3483	tryptophan 2,3-dioxygenase activity
H7F35_RS00940	COG0523	cobalamin synthesis protein
H7F35_RS00960	COG3639	organic phosphonate transmembrane transporter activity
H7F35_RS00965	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
H7F35_RS00970	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
H7F35_RS00975	COG3454	Phosphonate metabolism
H7F35_RS00980	COG4778	phosphonate C-P lyase system protein PhnL
H7F35_RS00985	COG4107	phosphonate C-P lyase system protein PhnK
H7F35_RS00990	COG3627	carbon phosphorus lyase activity
H7F35_RS00995	COG3626	phosphonate metabolism
H7F35_RS01005	COG3624	Phosphonate C-P lyase system protein PhnG
H7F35_RS01010	COG1609	Transcriptional regulator
H7F35_RS01015	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
H7F35_RS01020	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
H7F35_RS01025	COG1028	Short-chain dehydrogenase reductase Sdr
H7F35_RS01085	COG2354	Protein conserved in bacteria
H7F35_RS01105	COG4628	conserved protein (DUF2132)
H7F35_RS01120	COG0564	pseudouridine synthase activity
H7F35_RS01125	COG0589	response to stress
H7F35_RS01140	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
H7F35_RS01145	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H7F35_RS01150	COG1252	NADH dehydrogenase
H7F35_RS01165	COG1525	nuclease
H7F35_RS01175	COG0318	PFAM AMP-dependent synthetase and ligase
H7F35_RS01185	COG1764	response to oxidative stress
H7F35_RS01195	COG1028	Short-chain dehydrogenase reductase Sdr
H7F35_RS01205	COG2271	Major facilitator Superfamily
H7F35_RS01220	COG0765	amino acid transport
H7F35_RS01225	COG0765	amino acid transport
H7F35_RS01250	COG0583	DNA-binding transcription factor activity
H7F35_RS01270	COG0584	glycerophosphoryl diester phosphodiesterase
H7F35_RS01290	COG2132	Multicopper oxidase
H7F35_RS01310	COG0825	malonyl-CoA metabolic process
H7F35_RS01320	COG3191	aminopeptidase activity
H7F35_RS01335	COG0789	Transcriptional regulator
H7F35_RS01345	COG0488	(ABC) transporter
H7F35_RS01350	COG0513	Belongs to the DEAD box helicase family
H7F35_RS01360	COG3842	ATPase activity
H7F35_RS01370	COG1175	transmembrane transport
H7F35_RS01380	COG2186	Transcriptional regulator
H7F35_RS01385	COG0129	dihydroxy-acid dehydratase activity
H7F35_RS01390	COG3734	2-keto-3-deoxy-galactonokinase
H7F35_RS01395	COG0800	Aldolase
H7F35_RS01400	COG0235	Class ii aldolase
H7F35_RS01410	COG1028	Short-chain dehydrogenase reductase Sdr
H7F35_RS01420	COG2271	Major facilitator Superfamily
H7F35_RS01435	COG1840	ABC-type Fe3 transport system, periplasmic component
H7F35_RS01445	COG3842	ATPase activity
H7F35_RS01455	COG0346	lactoylglutathione lyase activity
H7F35_RS01530	COG0800	Aldolase
H7F35_RS01555	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
H7F35_RS01560	COG0259	pyridoxamine-phosphate oxidase activity
H7F35_RS01600	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
H7F35_RS01605	COG1309	transcriptional regulator
H7F35_RS01610	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
H7F35_RS01615	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H7F35_RS01635	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
H7F35_RS01645	COG0697	spore germination
H7F35_RS01655	COG0318	PFAM AMP-dependent synthetase and ligase
H7F35_RS01660	COG0318	PFAM AMP-dependent synthetase and ligase
H7F35_RS01665	COG3268	Saccharopine dehydrogenase
H7F35_RS01690	COG0625	glutathione transferase activity
H7F35_RS01700	COG2366	antibiotic biosynthetic process
H7F35_RS01725	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
H7F35_RS01730	COG4774	siderophore transport
H7F35_RS01740	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H7F35_RS01820	COG3181	Tripartite tricarboxylate transporter family receptor
H7F35_RS01830	COG2311	Membrane
H7F35_RS01845	COG0778	Nitroreductase
H7F35_RS01875	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H7F35_RS01900	COG0285	dihydrofolate synthase activity
H7F35_RS01905	COG1393	Belongs to the ArsC family
H7F35_RS01915	COG3123	guanosine phosphorylase activity
H7F35_RS01920	COG0137	argininosuccinate synthase activity
H7F35_RS01930	COG0812	UDP-N-acetylmuramate dehydrogenase activity
H7F35_RS01935	COG1666	GTP binding
H7F35_RS01945	COG0251	oxidation-reduction process
H7F35_RS01950	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
H7F35_RS01960	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
H7F35_RS01965	COG0667	Aldo Keto reductase
H7F35_RS01970	COG2267	carboxylic ester hydrolase activity
H7F35_RS01985	COG0667	Aldo Keto reductase
H7F35_RS01990	COG0583	DNA-binding transcription factor activity
H7F35_RS01995	COG1464	Belongs to the NlpA lipoprotein family
H7F35_RS02010	COG1464	Belongs to the NlpA lipoprotein family
H7F35_RS02015	COG2011	ABC-type metal ion transport system permease component
H7F35_RS02020	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H7F35_RS02025	COG1464	Belongs to the NlpA lipoprotein family
H7F35_RS02035	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H7F35_RS02040	COG0308	aminopeptidase N
H7F35_RS02045	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
H7F35_RS02135	COG1301	dicarboxylic acid transport
H7F35_RS02155	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H7F35_RS02160	COG4948	Mandelate Racemase Muconate Lactonizing
H7F35_RS02165	COG0583	DNA-binding transcription factor activity
H7F35_RS02205	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H7F35_RS02215	COG3302	dmso reductase anchor subunit
H7F35_RS02220	COG0437	4 iron, 4 sulfur cluster binding
H7F35_RS02225	COG0243	molybdopterin cofactor binding
H7F35_RS02230	COG0583	DNA-binding transcription factor activity
H7F35_RS02235	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
H7F35_RS02245	COG1414	Transcriptional regulator
H7F35_RS02270	COG1012	belongs to the aldehyde dehydrogenase family
H7F35_RS02275	COG0318	PFAM AMP-dependent synthetase and ligase
H7F35_RS02300	COG1414	Transcriptional regulator
H7F35_RS02305	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
H7F35_RS02330	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
H7F35_RS02340	COG2877	3-deoxy-8-phosphooctulonate synthase activity
H7F35_RS02345	COG1686	Belongs to the peptidase S11 family
H7F35_RS02390	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H7F35_RS02395	COG2271	Major facilitator Superfamily
H7F35_RS02400	COG4771	TonB-dependent receptor
H7F35_RS02445	COG0024	Methionine aminopeptidase
H7F35_RS02505	COG0583	DNA-binding transcription factor activity
H7F35_RS02510	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H7F35_RS02515	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
H7F35_RS02520	COG4521	taurine ABC transporter
H7F35_RS02525	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H7F35_RS02550	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H7F35_RS02555	COG0444	Belongs to the ABC transporter superfamily
H7F35_RS02560	COG4608	Belongs to the ABC transporter superfamily
H7F35_RS02565	COG1228	amidohydrolase
H7F35_RS02605	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
H7F35_RS02630	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
H7F35_RS02640	COG1253	flavin adenine dinucleotide binding
H7F35_RS02645	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
H7F35_RS02650	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H7F35_RS02670	COG1116	anion transmembrane transporter activity
H7F35_RS02675	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H7F35_RS02680	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H7F35_RS02695	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H7F35_RS02700	COG1960	acyl-CoA dehydrogenase activity
H7F35_RS02705	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H7F35_RS02725	COG0513	Belongs to the DEAD box helicase family
H7F35_RS02730	COG2321	neutral zinc metallopeptidase
H7F35_RS02735	COG0717	Belongs to the dCTP deaminase family
H7F35_RS02745	COG0402	S-adenosylhomocysteine deaminase activity
H7F35_RS02760	COG0583	DNA-binding transcription factor activity
H7F35_RS02775	COG2366	antibiotic biosynthetic process
H7F35_RS02780	COG4977	sequence-specific DNA binding
H7F35_RS02785	COG0583	DNA-binding transcription factor activity
H7F35_RS02790	COG2814	Major facilitator Superfamily
H7F35_RS02795	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
H7F35_RS02830	COG3845	ABC transporter
H7F35_RS02835	COG2252	PERMEase
H7F35_RS02845	COG1529	Aldehyde oxidase and xanthine dehydrogenase
H7F35_RS02855	COG0730	response to heat
H7F35_RS02870	COG3181	Tripartite tricarboxylate transporter family receptor
H7F35_RS02900	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H7F35_RS02920	COG1285	pathogenesis
H7F35_RS02950	COG2351	hydroxyisourate hydrolase activity
H7F35_RS02955	COG2186	Transcriptional regulator
H7F35_RS02970	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H7F35_RS02990	COG1953	Uracil, thiamine, allantoin
H7F35_RS03005	COG5001	Diguanylate cyclase
H7F35_RS03010	COG2233	PERMEase
H7F35_RS03015	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
H7F35_RS03020	COG0346	lactoylglutathione lyase activity
H7F35_RS03030	COG0656	L-ascorbic acid biosynthetic process
H7F35_RS03040	COG0473	3-isopropylmalate dehydrogenase activity
H7F35_RS03050	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H7F35_RS03055	COG0444	Belongs to the ABC transporter superfamily
H7F35_RS03060	COG4608	Belongs to the ABC transporter superfamily
H7F35_RS03065	COG0747	negative chemotaxis
H7F35_RS03070	COG0154	amidase activity
H7F35_RS03080	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
H7F35_RS03095	COG0583	DNA-binding transcription factor activity
H7F35_RS03130	COG0477	Major facilitator Superfamily
H7F35_RS03135	COG1752	Esterase of the alpha-beta hydrolase superfamily
H7F35_RS03140	COG1301	dicarboxylic acid transport
H7F35_RS03150	COG0628	permease
H7F35_RS03165	COG0583	DNA-binding transcription factor activity
H7F35_RS03170	COG3960	tartronate-semialdehyde synthase activity
H7F35_RS03175	COG3622	Belongs to the hyi family
H7F35_RS03180	COG2084	Dehydrogenase
H7F35_RS03190	COG0281	malic enzyme
H7F35_RS03190	COG0280	phosphate acetyltransferase
H7F35_RS03210	COG1414	Transcriptional regulator
H7F35_RS03220	COG1116	anion transmembrane transporter activity
H7F35_RS03225	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H7F35_RS03250	COG0745	RESPONSE REGULATOR receiver
H7F35_RS03260	COG3193	protein, possibly involved in utilization of glycolate and propanediol
H7F35_RS03295	COG1733	regulation of RNA biosynthetic process
H7F35_RS03320	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H7F35_RS03330	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H7F35_RS03340	COG0829	nickel cation binding
H7F35_RS03355	COG0189	ligase activity
H7F35_RS03355	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H7F35_RS03365	COG2814	Major facilitator Superfamily
H7F35_RS03375	COG0583	DNA-binding transcription factor activity
H7F35_RS03420	COG2855	membrane
H7F35_RS03435	COG2879	small protein
H7F35_RS03440	COG1966	Carbon starvation protein
H7F35_RS03455	COG0791	NLP P60 protein
H7F35_RS03465	COG0583	DNA-binding transcription factor activity
H7F35_RS03500	COG2207	Transcriptional regulator
H7F35_RS03505	COG0300	oxidoreductase activity
H7F35_RS03555	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H7F35_RS03570	COG2814	Major facilitator Superfamily
H7F35_RS03580	COG5002	protein histidine kinase activity
H7F35_RS03600	COG1538	Outer membrane efflux protein
H7F35_RS03605	COG0667	Aldo Keto reductase
H7F35_RS03615	COG1595	DNA-templated transcription, initiation
H7F35_RS03625	COG2814	Major facilitator Superfamily
H7F35_RS03635	COG1129	ABC transporter
H7F35_RS03660	COG0477	Major facilitator Superfamily
H7F35_RS03685	COG0306	phosphate transporter
H7F35_RS03695	COG0613	PHP domain protein
H7F35_RS03705	COG0009	L-threonylcarbamoyladenylate synthase
H7F35_RS03710	COG1994	Peptidase M50
H7F35_RS03715	COG0180	Tryptophanyl-tRNA synthetase
H7F35_RS03720	COG2197	response regulator
H7F35_RS03725	COG2198	Histidine kinase
H7F35_RS03725	COG2205	protein histidine kinase activity
H7F35_RS03725	COG0784	Response regulator, receiver
H7F35_RS03735	COG1950	PFAM Membrane protein of
H7F35_RS03740	COG0445	tRNA wobble uridine modification
H7F35_RS03750	COG0583	DNA-binding transcription factor activity
H7F35_RS03775	COG3386	PFAM SMP-30 Gluconolaconase
H7F35_RS03780	COG1609	Transcriptional regulator
H7F35_RS03790	COG1063	alcohol dehydrogenase
H7F35_RS03795	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H7F35_RS03800	COG1028	Short-chain dehydrogenase reductase Sdr
H7F35_RS03805	COG3265	gluconokinase activity
H7F35_RS03810	COG2084	Dehydrogenase
H7F35_RS03820	COG1191	sigma factor activity
H7F35_RS03835	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
H7F35_RS03845	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
H7F35_RS03860	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
H7F35_RS03865	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
H7F35_RS03870	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
H7F35_RS03875	COG0643	Histidine kinase
H7F35_RS03875	COG2198	Histidine kinase
H7F35_RS03900	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
H7F35_RS03920	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
H7F35_RS03935	COG1677	Flagellar hook-basal body complex protein FliE
H7F35_RS03940	COG1766	The M ring may be actively involved in energy transduction
H7F35_RS03960	COG2882	bacterial-type flagellum organization
H7F35_RS03970	COG1580	Controls the rotational direction of flagella during chemotaxis
H7F35_RS03980	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
H7F35_RS04010	COG1256	bacterial-type flagellum assembly
H7F35_RS04040	COG0840	transmembrane signaling receptor activity
H7F35_RS04065	COG0835	chemotaxis
H7F35_RS04075	COG1706	bacterial-type flagellum-dependent cell motility
H7F35_RS04080	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
H7F35_RS04105	COG1558	bacterial-type flagellum-dependent cell motility
H7F35_RS04110	COG1815	bacterial-type flagellum-dependent cell motility
H7F35_RS04140	COG1172	Belongs to the binding-protein-dependent transport system permease family
H7F35_RS04145	COG0559	Belongs to the binding-protein-dependent transport system permease family
H7F35_RS04165	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H7F35_RS04240	COG1301	dicarboxylic acid transport
H7F35_RS04250	COG1301	dicarboxylic acid transport
H7F35_RS04290	COG4585	Histidine kinase
H7F35_RS04310	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
H7F35_RS04315	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H7F35_RS04320	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
H7F35_RS04325	COG1047	Peptidyl-prolyl cis-trans
H7F35_RS04330	COG2003	Belongs to the UPF0758 family
H7F35_RS04355	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
H7F35_RS04365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7F35_RS04370	COG0765	amino acid transport
H7F35_RS04375	COG0765	amino acid transport
H7F35_RS04385	COG3491	Belongs to the iron ascorbate-dependent oxidoreductase family
H7F35_RS04395	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H7F35_RS04400	COG0477	Major facilitator Superfamily
H7F35_RS04405	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H7F35_RS04410	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H7F35_RS04415	COG1845	cytochrome c oxidase, subunit III
H7F35_RS04420	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
H7F35_RS04435	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
H7F35_RS04440	COG1272	protein, Hemolysin III
H7F35_RS04445	COG2900	Belongs to the SlyX family
H7F35_RS04450	COG1028	Short-chain dehydrogenase reductase Sdr
H7F35_RS04455	COG1028	Short-chain dehydrogenase reductase Sdr
H7F35_RS04460	COG0583	DNA-binding transcription factor activity
H7F35_RS04465	COG0477	Major facilitator Superfamily
H7F35_RS04470	COG0583	DNA-binding transcription factor activity
H7F35_RS04480	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
H7F35_RS04495	COG0437	4 iron, 4 sulfur cluster binding
H7F35_RS04500	COG2864	formate dehydrogenase
H7F35_RS04530	COG3276	selenocysteine insertion sequence binding
H7F35_RS04545	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
H7F35_RS04550	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
H7F35_RS04555	COG3639	organic phosphonate transmembrane transporter activity
H7F35_RS04560	COG3639	organic phosphonate transmembrane transporter activity
H7F35_RS04565	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
H7F35_RS04570	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
H7F35_RS04580	COG0243	molybdopterin cofactor binding
H7F35_RS04590	COG0725	ABC transporter, periplasmic molybdate-binding protein
H7F35_RS04595	COG4149	molybdate abc transporter
H7F35_RS04605	COG0778	Nitroreductase
H7F35_RS04620	COG0583	DNA-binding transcription factor activity
H7F35_RS04625	COG0489	protein tyrosine kinase activity
H7F35_RS04635	COG1473	amidohydrolase
H7F35_RS04640	COG3548	integral membrane protein
H7F35_RS04660	COG3132	Protein of unknown function, DUF480
H7F35_RS04670	COG0473	3-isopropylmalate dehydrogenase activity
H7F35_RS04675	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
H7F35_RS04680	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H7F35_RS04680	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H7F35_RS04690	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
H7F35_RS04690	COG1024	Enoyl-CoA hydratase
H7F35_RS04695	COG0659	secondary active sulfate transmembrane transporter activity
H7F35_RS04715	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
H7F35_RS04720	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
H7F35_RS04725	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
H7F35_RS04730	COG0602	queuosine metabolic process
H7F35_RS04740	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
H7F35_RS04750	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
H7F35_RS04755	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
H7F35_RS04765	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H7F35_RS04770	COG0588	phosphoglycerate mutase activity
H7F35_RS04775	COG0793	Belongs to the peptidase S41A family
H7F35_RS04780	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
H7F35_RS04785	COG2982	Protein involved in outer membrane biogenesis
H7F35_RS04795	COG2197	response regulator
H7F35_RS04830	COG2823	Periplasmic or secreted lipoprotein
H7F35_RS04865	COG0494	nUDIX hydrolase
H7F35_RS04870	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
H7F35_RS04885	COG1177	transmembrane transport
H7F35_RS04890	COG1176	ABC-type spermidine putrescine transport system, permease component I
H7F35_RS04895	COG3842	ATPase activity
H7F35_RS04900	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
H7F35_RS04905	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
H7F35_RS04920	COG2226	methyltransferase
H7F35_RS04940	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H7F35_RS04955	COG0395	ABC-type sugar transport system, permease component
H7F35_RS04960	COG3842	ATPase activity
H7F35_RS04965	COG0584	glycerophosphoryl diester phosphodiesterase
H7F35_RS04970	COG1511	domain protein
H7F35_RS04970	COG3264	Mechanosensitive ion channel
H7F35_RS04975	COG1522	sequence-specific DNA binding
H7F35_RS04985	COG4120	Belongs to the binding-protein-dependent transport system permease family
H7F35_RS04990	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
H7F35_RS05005	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
H7F35_RS05010	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
H7F35_RS05015	COG2890	protein-(glutamine-N5) methyltransferase activity
H7F35_RS05020	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
H7F35_RS05030	COG1253	flavin adenine dinucleotide binding
H7F35_RS05035	COG0741	lytic transglycosylase activity
H7F35_RS05040	COG0442	prolyl-tRNA aminoacylation
H7F35_RS05045	COG0494	nUDIX hydrolase
H7F35_RS05055	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
H7F35_RS05060	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
H7F35_RS05065	COG0211	Belongs to the bacterial ribosomal protein bL27 family
H7F35_RS05070	COG0261	This protein binds to 23S rRNA in the presence of protein L20
H7F35_RS05075	COG0142	geranyltranstransferase activity
H7F35_RS05095	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
H7F35_RS05105	COG1696	Membrane protein involved in D-alanine export
H7F35_RS05115	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
H7F35_RS05120	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
H7F35_RS05125	COG2755	lipolytic protein G-D-S-L family
H7F35_RS05125	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
H7F35_RS05130	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
H7F35_RS05130	COG2755	lipolytic protein G-D-S-L family
H7F35_RS05135	COG0494	nUDIX hydrolase
H7F35_RS05145	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
H7F35_RS05150	COG0653	protein targeting
H7F35_RS05165	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
H7F35_RS05175	COG3181	Tripartite tricarboxylate transporter family receptor
H7F35_RS05180	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H7F35_RS05185	COG0583	DNA-binding transcription factor activity
H7F35_RS05205	COG0831	urea catabolic process
H7F35_RS05215	COG0832	Belongs to the urease beta subunit family
H7F35_RS05220	COG0804	urea catabolic process
H7F35_RS05225	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
H7F35_RS05230	COG0830	nickel cation binding
H7F35_RS05235	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
H7F35_RS05250	COG0583	DNA-binding transcription factor activity
H7F35_RS05295	COG0745	RESPONSE REGULATOR receiver
H7F35_RS05305	COG2205	protein histidine kinase activity
H7F35_RS05310	COG0745	RESPONSE REGULATOR receiver
H7F35_RS05320	COG0384	phenazine biosynthesis protein PhzF
H7F35_RS05355	COG1309	transcriptional regulator
H7F35_RS05365	COG0493	'glutamate synthase
H7F35_RS05375	COG1953	Uracil, thiamine, allantoin
H7F35_RS05420	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H7F35_RS05455	COG0789	Transcriptional regulator
H7F35_RS05475	COG0789	Transcriptional regulator
H7F35_RS05485	COG1289	transmembrane transporter activity
H7F35_RS05490	COG1335	isochorismatase
H7F35_RS05495	COG1335	isochorismatase
H7F35_RS05510	COG1959	2 iron, 2 sulfur cluster binding
H7F35_RS05520	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H7F35_RS05545	COG4773	Receptor
H7F35_RS05550	COG3712	iron ion homeostasis
H7F35_RS05555	COG1595	DNA-templated transcription, initiation
H7F35_RS05670	COG4373	Mu-like prophage FluMu protein gp28
H7F35_RS05730	COG1396	sequence-specific DNA binding
H7F35_RS05820	COG5566	PFAM Mor transcription activator
H7F35_RS05830	COG3712	iron ion homeostasis
H7F35_RS05835	COG1595	DNA-templated transcription, initiation
H7F35_RS05855	COG4977	sequence-specific DNA binding
H7F35_RS05855	COG1917	Cupin 2, conserved barrel domain protein
H7F35_RS05865	COG0477	Major facilitator Superfamily
H7F35_RS05890	COG2133	pyrroloquinoline quinone binding
H7F35_RS05900	COG2226	methyltransferase
H7F35_RS05905	COG2832	Protein of unknown function (DUF454)
H7F35_RS05945	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H7F35_RS05950	COG2814	Major facilitator Superfamily
H7F35_RS05995	COG1126	abc transporter atp-binding protein
H7F35_RS06000	COG0765	amino acid transport
H7F35_RS06005	COG0626	cystathionine gamma-synthase activity
H7F35_RS06010	COG0583	DNA-binding transcription factor activity
H7F35_RS06015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7F35_RS06035	COG0384	phenazine biosynthesis protein PhzF
H7F35_RS06040	COG2207	Transcriptional regulator
H7F35_RS06045	COG1289	transmembrane transporter activity
H7F35_RS06055	COG1566	PFAM secretion protein HlyD family protein
H7F35_RS06065	COG0583	DNA-binding transcription factor activity
H7F35_RS06075	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H7F35_RS06080	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
H7F35_RS06085	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
H7F35_RS06100	COG1561	YicC-like family, N-terminal region
H7F35_RS06105	COG0194	GDP metabolic process
H7F35_RS06110	COG1758	RNA polymerase activity
H7F35_RS06115	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H7F35_RS06140	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H7F35_RS06145	COG3181	Tripartite tricarboxylate transporter family receptor
H7F35_RS06150	COG0583	DNA-binding transcription factor activity
H7F35_RS06155	COG3181	Tripartite tricarboxylate transporter family receptor
H7F35_RS06200	COG0251	oxidation-reduction process
H7F35_RS06220	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
H7F35_RS06220	COG0674	pyruvate-flavodoxin oxidoreductase activity
H7F35_RS06230	COG2207	Transcriptional regulator
H7F35_RS06230	COG3708	Transcriptional regulator
H7F35_RS06235	COG0697	spore germination
H7F35_RS06245	COG1420	regulation of RNA biosynthetic process
H7F35_RS06250	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
H7F35_RS06255	COG0497	DNA recombination
H7F35_RS06260	COG1660	Displays ATPase and GTPase activities
H7F35_RS06270	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
H7F35_RS06275	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
H7F35_RS06290	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
H7F35_RS06300	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H7F35_RS06305	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
H7F35_RS06310	COG0193	aminoacyl-tRNA hydrolase activity
H7F35_RS06320	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H7F35_RS06330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H7F35_RS06340	COG4608	Belongs to the ABC transporter superfamily
H7F35_RS06345	COG0747	negative chemotaxis
H7F35_RS06355	COG0154	amidase activity
H7F35_RS06360	COG0583	DNA-binding transcription factor activity
H7F35_RS06385	COG2267	carboxylic ester hydrolase activity
H7F35_RS06390	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
H7F35_RS06405	COG0583	DNA-binding transcription factor activity
H7F35_RS06410	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
H7F35_RS06415	COG1984	allophanate hydrolase subunit 2
H7F35_RS06420	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
H7F35_RS06425	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
H7F35_RS06430	COG0742	ribosomal rna small subunit methyltransferase
H7F35_RS06445	COG0612	Peptidase, M16
H7F35_RS06450	COG0612	Peptidase, M16
H7F35_RS06460	COG0784	Response regulator, receiver
H7F35_RS06460	COG2205	protein histidine kinase activity
H7F35_RS06465	COG2197	response regulator
H7F35_RS06485	COG3842	ATPase activity
H7F35_RS06490	COG0583	DNA-binding transcription factor activity
H7F35_RS06500	COG4335	DNA alkylation repair
H7F35_RS06505	COG1999	signal sequence binding
H7F35_RS06510	COG0109	protoheme IX farnesyltransferase activity
H7F35_RS06545	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
H7F35_RS06550	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H7F35_RS06555	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H7F35_RS06565	COG2226	methyltransferase
H7F35_RS06575	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
H7F35_RS06590	COG0489	protein tyrosine kinase activity
H7F35_RS06610	COG3181	Tripartite tricarboxylate transporter family receptor
H7F35_RS06625	COG1024	Enoyl-CoA hydratase
H7F35_RS06640	COG0683	leucine binding
H7F35_RS06665	COG1960	acyl-CoA dehydrogenase activity
H7F35_RS06680	COG2764	glyoxalase bleomycin resistance protein dioxygenase
H7F35_RS06700	COG5507	3-demethylubiquinone-9 3-methyltransferase
H7F35_RS06710	COG3485	protocatechuate 3,4-dioxygenase
H7F35_RS06715	COG3411	Ferredoxin
H7F35_RS06745	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
H7F35_RS06780	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
H7F35_RS06800	COG2814	Major facilitator Superfamily
H7F35_RS06805	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H7F35_RS06825	COG0430	RNA-3'-phosphate cyclase activity
H7F35_RS06830	COG3541	Predicted nucleotidyltransferase
H7F35_RS06835	COG1234	tRNA 3'-trailer cleavage
H7F35_RS06845	COG1690	Belongs to the RtcB family
H7F35_RS06860	COG4650	regulator
H7F35_RS06880	COG1073	alpha beta
H7F35_RS06895	COG2226	methyltransferase
H7F35_RS06905	COG0456	acetyltransferase
H7F35_RS06915	COG0693	protein deglycase activity
H7F35_RS06930	COG0183	Belongs to the thiolase family
H7F35_RS06935	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H7F35_RS06945	COG1414	Transcriptional regulator
H7F35_RS06975	COG1137	ATPase activity
H7F35_RS06985	COG1012	belongs to the aldehyde dehydrogenase family
H7F35_RS07005	COG3063	Type IV pilus biogenesis stability protein PilW
H7F35_RS07030	COG4964	Belongs to the GSP D family
H7F35_RS07090	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H7F35_RS07095	COG2274	protein secretion by the type I secretion system
H7F35_RS07105	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H7F35_RS07125	COG0583	DNA-binding transcription factor activity
H7F35_RS07130	COG3485	protocatechuate 3,4-dioxygenase
H7F35_RS07135	COG3485	protocatechuate 3,4-dioxygenase
H7F35_RS07145	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H7F35_RS07215	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H7F35_RS07225	COG0840	transmembrane signaling receptor activity
H7F35_RS07245	COG1902	pentaerythritol trinitrate reductase activity
H7F35_RS07250	COG0697	spore germination
H7F35_RS07280	COG1028	Short-chain dehydrogenase reductase Sdr
H7F35_RS07285	COG1053	succinate dehydrogenase
H7F35_RS07305	COG0540	Belongs to the ATCase OTCase family
H7F35_RS07310	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
H7F35_RS07315	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
H7F35_RS07320	COG1678	Uncharacterized ACR, COG1678
H7F35_RS07325	COG0415	Belongs to the DNA photolyase family
H7F35_RS07330	COG2198	Histidine kinase
H7F35_RS07330	COG0784	Response regulator, receiver
H7F35_RS07330	COG0643	Histidine kinase
H7F35_RS07335	COG0840	transmembrane signaling receptor activity
H7F35_RS07355	COG1773	rubredoxin
H7F35_RS07365	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
H7F35_RS07375	COG0138	bifunctional purine biosynthesis protein purh
H7F35_RS07385	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H7F35_RS07390	COG1238	metal cluster binding
H7F35_RS07410	COG0012	GTP binding
H7F35_RS07415	COG1879	ABC-type sugar transport system periplasmic component
H7F35_RS07420	COG1129	ABC transporter
H7F35_RS07425	COG1172	Belongs to the binding-protein-dependent transport system permease family
H7F35_RS07430	COG1609	Transcriptional regulator
H7F35_RS07435	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H7F35_RS07440	COG1869	D-ribose catabolic process
H7F35_RS07450	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H7F35_RS07470	COG2076	Multidrug Resistance protein
H7F35_RS07475	COG1024	Enoyl-CoA hydratase
H7F35_RS07515	COG1999	signal sequence binding
H7F35_RS07535	COG0318	PFAM AMP-dependent synthetase and ligase
H7F35_RS07540	COG0778	Nitroreductase
H7F35_RS07540	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
H7F35_RS07545	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H7F35_RS07585	COG0183	Belongs to the thiolase family
H7F35_RS07595	COG2909	trisaccharide binding
H7F35_RS07620	COG0318	PFAM AMP-dependent synthetase and ligase
H7F35_RS07625	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H7F35_RS07630	COG1960	acyl-CoA dehydrogenase activity
H7F35_RS07635	COG1960	acyl-CoA dehydrogenase activity
H7F35_RS07660	COG2255	four-way junction helicase activity
H7F35_RS07665	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H7F35_RS07670	COG2267	carboxylic ester hydrolase activity
H7F35_RS07675	COG0671	phosphoesterase, PA-phosphatase related
H7F35_RS07675	COG2453	phosphatase
H7F35_RS07690	COG4589	Belongs to the CDS family
H7F35_RS07745	COG0632	four-way junction helicase activity
H7F35_RS07750	COG1702	phosphate starvation-inducible protein PhoH
H7F35_RS07755	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
H7F35_RS07765	COG1490	D-aminoacyl-tRNA deacylase activity
H7F35_RS07770	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
H7F35_RS07785	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
H7F35_RS07795	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
H7F35_RS07800	COG2814	Major facilitator Superfamily
H7F35_RS07805	COG0316	Belongs to the HesB IscA family
H7F35_RS07810	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
H7F35_RS07815	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
H7F35_RS07820	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H7F35_RS07830	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
H7F35_RS07835	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
H7F35_RS07845	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
H7F35_RS07850	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
H7F35_RS07880	COG3243	poly(R)-hydroxyalkanoic acid synthase
H7F35_RS07890	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
H7F35_RS07910	COG4555	ABC transporter
H7F35_RS07945	COG2423	ornithine cyclodeaminase activity
H7F35_RS07955	COG3181	Tripartite tricarboxylate transporter family receptor
H7F35_RS07960	COG0583	DNA-binding transcription factor activity
H7F35_RS07965	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
H7F35_RS07985	COG0477	Major facilitator Superfamily
H7F35_RS08005	COG1280	lysine exporter protein (LysE YggA)
H7F35_RS08020	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H7F35_RS08035	COG1414	Transcriptional regulator
H7F35_RS08040	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H7F35_RS08055	COG0625	glutathione transferase activity
H7F35_RS08080	COG1024	Enoyl-CoA hydratase
H7F35_RS08090	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H7F35_RS08095	COG0318	PFAM AMP-dependent synthetase and ligase
H7F35_RS08100	COG1960	acyl-CoA dehydrogenase activity
H7F35_RS08115	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H7F35_RS08125	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H7F35_RS08130	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
H7F35_RS08135	COG3012	SEC-C Motif Domain Protein
H7F35_RS08140	COG0784	Response regulator, receiver
H7F35_RS08140	COG2205	protein histidine kinase activity
H7F35_RS08155	COG1408	metallophosphoesterase
H7F35_RS08160	COG1960	acyl-CoA dehydrogenase activity
H7F35_RS08170	COG0183	Belongs to the thiolase family
H7F35_RS08175	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
H7F35_RS08180	COG0288	reversible hydration of carbon dioxide
H7F35_RS08220	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
H7F35_RS08225	COG0751	glycine-tRNA ligase activity
H7F35_RS08230	COG1988	membrane-bound metal-dependent
H7F35_RS08235	COG0752	glycyl-tRNA synthetase alpha subunit
H7F35_RS08270	COG0783	Belongs to the Dps family
H7F35_RS08355	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H7F35_RS08365	COG0815	Transfers the fatty acyl group on membrane lipoproteins
H7F35_RS08370	COG4535	Mg2 and Co2 transporter CorC
H7F35_RS08395	COG3186	Phenylalanine-4-hydroxylase
H7F35_RS08400	COG0318	PFAM AMP-dependent synthetase and ligase
H7F35_RS08435	COG0488	(ABC) transporter
H7F35_RS08440	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H7F35_RS08450	COG4774	siderophore transport
H7F35_RS08470	COG2095	MarC family integral membrane protein
H7F35_RS08490	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H7F35_RS08500	COG0501	Belongs to the peptidase M48B family
H7F35_RS08535	COG1462	curli production assembly transport component CsgG
H7F35_RS08545	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
H7F35_RS08565	COG0439	Biotin carboxylase
H7F35_RS08570	COG0318	PFAM AMP-dependent synthetase and ligase
H7F35_RS08585	COG2124	cytochrome p450
H7F35_RS08585	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
H7F35_RS08600	COG1309	transcriptional regulator
H7F35_RS08620	COG1505	serine-type exopeptidase activity
H7F35_RS08630	COG0745	RESPONSE REGULATOR receiver
H7F35_RS08635	COG2205	protein histidine kinase activity
H7F35_RS08645	COG0010	Belongs to the arginase family
H7F35_RS08650	COG1289	transmembrane transporter activity
H7F35_RS08665	COG0572	uridine kinase
H7F35_RS08680	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H7F35_RS08720	COG0789	Transcriptional regulator
H7F35_RS08725	COG2084	Dehydrogenase
H7F35_RS08735	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
H7F35_RS08740	COG0792	nuclease activity
H7F35_RS08745	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
H7F35_RS08810	COG1309	transcriptional regulator
H7F35_RS08815	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H7F35_RS08850	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H7F35_RS08855	COG1335	isochorismatase
H7F35_RS08860	COG0251	oxidation-reduction process
H7F35_RS08865	COG2267	carboxylic ester hydrolase activity
H7F35_RS08870	COG0778	Nitroreductase
H7F35_RS08875	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H7F35_RS08880	COG1309	transcriptional regulator
H7F35_RS08900	COG3845	ABC transporter
H7F35_RS08910	COG1079	Belongs to the binding-protein-dependent transport system permease family
H7F35_RS08945	COG3118	belongs to the thioredoxin family
H7F35_RS08950	COG1201	RNA secondary structure unwinding
H7F35_RS08955	COG1793	dna ligase
H7F35_RS08960	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
H7F35_RS08960	COG1793	dna ligase
H7F35_RS08980	COG1879	ABC-type sugar transport system periplasmic component
H7F35_RS08985	COG1172	Belongs to the binding-protein-dependent transport system permease family
H7F35_RS09000	COG0355	proton-transporting ATP synthase activity, rotational mechanism
H7F35_RS09005	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
H7F35_RS09015	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
H7F35_RS09020	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
H7F35_RS09025	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
H7F35_RS09030	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
H7F35_RS09040	COG0356	it plays a direct role in the translocation of protons across the membrane
H7F35_RS09050	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H7F35_RS09055	COG2921	Belongs to the UPF0250 family
H7F35_RS09060	COG0321	lipoyl(octanoyl) transferase activity
H7F35_RS09065	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
H7F35_RS09085	COG0318	PFAM AMP-dependent synthetase and ligase
H7F35_RS09090	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
H7F35_RS09135	COG2130	NADP-dependent
H7F35_RS09145	COG0745	RESPONSE REGULATOR receiver
H7F35_RS09175	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H7F35_RS09185	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7F35_RS09200	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H7F35_RS09205	COG3909	cytochrome
H7F35_RS09220	COG0678	peroxiredoxin activity
H7F35_RS09225	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
H7F35_RS09230	COG0255	Belongs to the universal ribosomal protein uL29 family
H7F35_RS09235	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
H7F35_RS09240	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
H7F35_RS09245	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
H7F35_RS09250	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
H7F35_RS09255	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
H7F35_RS09260	COG0089	rRNA binding
H7F35_RS09265	COG0088	Forms part of the polypeptide exit tunnel
H7F35_RS09270	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
H7F35_RS09285	COG0051	transcription antitermination factor activity, RNA binding
H7F35_RS09290	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
H7F35_RS09295	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
H7F35_RS09300	COG0049	tRNA binding
H7F35_RS09305	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
H7F35_RS09310	COG1686	Belongs to the peptidase S11 family
H7F35_RS09315	COG2945	thiolester hydrolase activity
H7F35_RS09330	COG1981	membrane
H7F35_RS09345	COG0598	Magnesium transport protein CorA
H7F35_RS09360	COG0583	DNA-binding transcription factor activity
H7F35_RS09365	COG0412	Dienelactone hydrolase
H7F35_RS09375	COG1028	Short-chain dehydrogenase reductase Sdr
H7F35_RS09380	COG2095	MarC family integral membrane protein
H7F35_RS09415	COG0559	Belongs to the binding-protein-dependent transport system permease family
H7F35_RS09425	COG0657	acetylesterase activity
H7F35_RS09430	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
H7F35_RS09435	COG1250	3-hydroxyacyl-CoA dehydrogenase
H7F35_RS09450	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
H7F35_RS09455	COG1652	LysM domain
H7F35_RS09465	COG0640	Transcriptional regulator
H7F35_RS09475	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H7F35_RS09480	COG0574	Belongs to the PEP-utilizing enzyme family
H7F35_RS09480	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H7F35_RS09495	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
H7F35_RS09505	COG4208	sulfate ABC transporter
H7F35_RS09530	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
H7F35_RS09540	COG0640	Transcriptional regulator
H7F35_RS09555	COG0625	glutathione transferase activity
H7F35_RS09560	COG0583	DNA-binding transcription factor activity
H7F35_RS09575	COG1131	(ABC) transporter
H7F35_RS09590	COG1846	Transcriptional regulator
H7F35_RS09595	COG1764	response to oxidative stress
H7F35_RS09605	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H7F35_RS09610	COG0583	DNA-binding transcription factor activity
H7F35_RS09615	COG1960	acyl-CoA dehydrogenase activity
H7F35_RS09625	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H7F35_RS09665	COG3552	Protein containing von Willebrand factor type A (VWA) domain
H7F35_RS09670	COG2425	protein containing a von Willebrand factor type A (vWA) domain
H7F35_RS09675	COG0714	Associated with various cellular activities
H7F35_RS09695	COG0326	Molecular chaperone. Has ATPase activity
H7F35_RS09735	COG1840	ABC-type Fe3 transport system, periplasmic component
H7F35_RS09740	COG0583	DNA-binding transcription factor activity
H7F35_RS09750	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
H7F35_RS09760	COG0642	Histidine kinase
H7F35_RS09775	COG1187	pseudouridine synthase activity
H7F35_RS09780	COG1051	belongs to the nudix hydrolase family
H7F35_RS09780	COG1056	cytidyltransferase-related domain
H7F35_RS09790	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
H7F35_RS09820	COG0745	RESPONSE REGULATOR receiver
H7F35_RS09825	COG2205	protein histidine kinase activity
H7F35_RS09830	COG0477	Major facilitator Superfamily
H7F35_RS09845	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
H7F35_RS09850	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
H7F35_RS09855	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
H7F35_RS09865	COG1335	isochorismatase
H7F35_RS09875	COG2391	methyltransferase activity
H7F35_RS09905	COG4654	Cytochrome c, class I
H7F35_RS09910	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
H7F35_RS09915	COG4654	Cytochrome c, class I
H7F35_RS09940	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H7F35_RS09945	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H7F35_RS09960	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H7F35_RS09985	COG1028	Short-chain dehydrogenase reductase Sdr
H7F35_RS09995	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H7F35_RS10000	COG1022	Amp-dependent synthetase and ligase
H7F35_RS10030	COG0318	PFAM AMP-dependent synthetase and ligase
H7F35_RS10040	COG0372	Belongs to the citrate synthase family
H7F35_RS10070	COG1940	carbohydrate kinase activity
H7F35_RS10075	COG1129	ABC transporter
H7F35_RS10080	COG4214	carbohydrate transport
H7F35_RS10085	COG4213	ABC transporter substrate-binding protein
H7F35_RS10095	COG2197	response regulator
H7F35_RS10105	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H7F35_RS10110	COG0022	dehydrogenase e1 component
H7F35_RS10120	COG1028	Short-chain dehydrogenase reductase Sdr
H7F35_RS10125	COG0583	DNA-binding transcription factor activity
H7F35_RS10140	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
H7F35_RS10155	COG1024	Enoyl-CoA hydratase
H7F35_RS10160	COG1960	acyl-CoA dehydrogenase activity
H7F35_RS10190	COG0203	ribosomal protein L17
H7F35_RS10195	COG0202	RNA polymerase activity
H7F35_RS10200	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
H7F35_RS10205	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
H7F35_RS10210	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
H7F35_RS10215	COG0257	Belongs to the bacterial ribosomal protein bL36 family
H7F35_RS10220	COG0201	protein transport
H7F35_RS10225	COG0200	Binds to the 23S rRNA
H7F35_RS10230	COG1841	ribosomal large subunit assembly
H7F35_RS10235	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
H7F35_RS10240	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
H7F35_RS10245	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
H7F35_RS10250	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
H7F35_RS10255	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
H7F35_RS10260	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
H7F35_RS10265	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
H7F35_RS10270	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
H7F35_RS10290	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
H7F35_RS10295	COG0783	Belongs to the Dps family
H7F35_RS10305	COG4770	biotin carboxylase activity
H7F35_RS10310	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
H7F35_RS10315	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
H7F35_RS10320	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
H7F35_RS10345	COG1280	lysine exporter protein (LysE YggA)
H7F35_RS10350	COG1760	l-serine dehydratase
H7F35_RS10355	COG1840	ABC-type Fe3 transport system, periplasmic component
H7F35_RS10360	COG1178	ABC-type Fe3 transport system permease component
H7F35_RS10365	COG3842	ATPase activity
H7F35_RS10370	COG0583	DNA-binding transcription factor activity
H7F35_RS10375	COG0560	Phosphoserine phosphatase
H7F35_RS10380	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
H7F35_RS10385	COG1090	epimerase
H7F35_RS10395	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
H7F35_RS10400	COG0343	queuine tRNA-ribosyltransferase activity
H7F35_RS10450	COG0284	orotidine-5'-phosphate decarboxylase activity
H7F35_RS10465	COG1214	PFAM Peptidase M22, glycoprotease
H7F35_RS10470	COG1349	DNA-binding transcription factor activity
H7F35_RS10475	COG0494	nUDIX hydrolase
H7F35_RS10480	COG2027	D-alanyl-D-alanine carboxypeptidase
H7F35_RS10490	COG0009	L-threonylcarbamoyladenylate synthase
H7F35_RS10495	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
H7F35_RS10500	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
H7F35_RS10515	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
H7F35_RS10530	COG1522	sequence-specific DNA binding
H7F35_RS10535	COG2515	1-aminocyclopropane-1-carboxylate deaminase
H7F35_RS10540	COG0469	pyruvate kinase activity
H7F35_RS10545	COG0126	phosphoglycerate kinase activity
H7F35_RS10550	COG0583	DNA-binding transcription factor activity
H7F35_RS10565	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H7F35_RS10595	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
H7F35_RS10605	COG0242	peptide deformylase activity
H7F35_RS10615	COG0758	DNA mediated transformation
H7F35_RS10615	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
H7F35_RS10620	COG2922	Belongs to the Smg family
H7F35_RS10630	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H7F35_RS10635	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H7F35_RS10640	COG1862	Preprotein translocase
H7F35_RS10645	COG4804	nuclease activity
H7F35_RS10655	COG1522	sequence-specific DNA binding
H7F35_RS10675	COG0765	amino acid transport
H7F35_RS10680	COG2814	Major facilitator Superfamily
H7F35_RS10700	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H7F35_RS10730	COG0251	oxidation-reduction process
H7F35_RS10740	COG3622	Belongs to the hyi family
H7F35_RS10745	COG0235	Class ii aldolase
H7F35_RS10750	COG3395	kinase activity
H7F35_RS10755	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H7F35_RS10760	COG2084	Dehydrogenase
H7F35_RS10765	COG2186	Transcriptional regulator
H7F35_RS10775	COG1522	sequence-specific DNA binding
H7F35_RS10805	COG4566	intracellular signal transduction
H7F35_RS10825	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
H7F35_RS10830	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
H7F35_RS10835	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H7F35_RS10840	COG1595	DNA-templated transcription, initiation
H7F35_RS10865	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
H7F35_RS10880	COG0625	glutathione transferase activity
H7F35_RS10910	COG0861	Integral membrane protein TerC family
H7F35_RS10920	COG1950	PFAM Membrane protein of
H7F35_RS10925	COG4783	chaperone-mediated protein folding
H7F35_RS10930	COG0315	cyclic pyranopterin monophosphate synthase activity
H7F35_RS10985	COG1716	ATPase activity
H7F35_RS10995	COG0861	Integral membrane protein TerC family
H7F35_RS11000	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
H7F35_RS11005	COG0045	succinate-CoA ligase (ADP-forming) activity
H7F35_RS11010	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
H7F35_RS11020	COG4682	membrane
H7F35_RS11025	COG1414	Transcriptional regulator
H7F35_RS11030	COG2271	Major facilitator Superfamily
H7F35_RS11035	COG1028	Short-chain dehydrogenase reductase Sdr
H7F35_RS11050	COG2721	sulfolactate sulfo-lyase activity
H7F35_RS11055	COG0765	amino acid transport
H7F35_RS11060	COG0765	amino acid transport
H7F35_RS11065	COG1126	abc transporter atp-binding protein
H7F35_RS11085	COG2137	regulation of response to DNA damage stimulus
H7F35_RS11090	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
H7F35_RS11105	COG0642	Histidine kinase
H7F35_RS11115	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
H7F35_RS11115	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
H7F35_RS11125	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H7F35_RS11125	COG0551	DNA topoisomerase type I activity
H7F35_RS11135	COG0583	DNA-binding transcription factor activity
H7F35_RS11140	COG3181	Tripartite tricarboxylate transporter family receptor
H7F35_RS11165	COG1960	acyl-CoA dehydrogenase activity
H7F35_RS11175	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
H7F35_RS11195	COG2814	Major facilitator Superfamily
H7F35_RS11205	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
H7F35_RS11210	COG0513	Belongs to the DEAD box helicase family
H7F35_RS11250	COG0697	spore germination
H7F35_RS11260	COG1802	Transcriptional regulator
H7F35_RS11275	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H7F35_RS11290	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H7F35_RS11310	COG1473	amidohydrolase
H7F35_RS11315	COG1741	Belongs to the pirin family
H7F35_RS11330	COG0583	DNA-binding transcription factor activity
H7F35_RS11335	COG1047	Peptidyl-prolyl cis-trans
H7F35_RS11365	COG1914	H( )-stimulated, divalent metal cation uptake system
H7F35_RS11370	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
H7F35_RS11390	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H7F35_RS11395	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
H7F35_RS11400	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
H7F35_RS11405	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
H7F35_RS11410	COG0006	proline dipeptidase activity
H7F35_RS11420	COG0667	Aldo Keto reductase
H7F35_RS11565	COG4953	penicillin-binding protein 1C
H7F35_RS11575	COG2373	Large extracellular alpha-helical protein
H7F35_RS11600	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
H7F35_RS11620	COG0280	phosphate acetyltransferase
H7F35_RS11620	COG0281	malic enzyme
H7F35_RS11640	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
H7F35_RS11645	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H7F35_RS11650	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
H7F35_RS11660	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H7F35_RS11675	COG3831	ATPase activity
H7F35_RS11680	COG2814	Major facilitator Superfamily
H7F35_RS11685	COG2267	carboxylic ester hydrolase activity
H7F35_RS11705	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H7F35_RS11710	COG1739	Uncharacterized protein family UPF0029
H7F35_RS11715	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H7F35_RS11715	COG2813	Specifically methylates the guanine in position
H7F35_RS11720	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H7F35_RS11725	COG2119	membrane
H7F35_RS11730	COG0724	RNA recognition motif
H7F35_RS11735	COG4221	oxidoreductase activity
H7F35_RS11745	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
H7F35_RS11765	COG2066	Belongs to the glutaminase family
H7F35_RS11765	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
H7F35_RS11770	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
H7F35_RS11775	COG0706	membrane insertase activity
H7F35_RS11780	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
H7F35_RS11785	COG0594	ribonuclease P activity
H7F35_RS11790	COG0230	Belongs to the bacterial ribosomal protein bL34 family
H7F35_RS11795	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
H7F35_RS11800	COG0592	DNA-directed DNA polymerase activity
H7F35_RS11810	COG0542	response to heat
H7F35_RS11815	COG0542	response to heat
H7F35_RS11840	COG1408	metallophosphoesterase
H7F35_RS11850	COG0392	lysyltransferase activity
H7F35_RS11855	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H7F35_RS11860	COG3568	Endonuclease Exonuclease Phosphatase
H7F35_RS11895	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H7F35_RS11915	COG4452	Inner membrane protein CreD
H7F35_RS11920	COG1472	Belongs to the glycosyl hydrolase 3 family
H7F35_RS11935	COG2205	protein histidine kinase activity
H7F35_RS11940	COG0745	RESPONSE REGULATOR receiver
H7F35_RS11955	COG2608	mercury ion transmembrane transporter activity
H7F35_RS11970	COG0456	acetyltransferase
H7F35_RS11985	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H7F35_RS11995	COG0745	RESPONSE REGULATOR receiver
H7F35_RS12005	COG0346	lactoylglutathione lyase activity
H7F35_RS12020	COG1902	pentaerythritol trinitrate reductase activity
H7F35_RS12030	COG3181	Tripartite tricarboxylate transporter family receptor
H7F35_RS12040	COG1024	Enoyl-CoA hydratase
H7F35_RS12050	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H7F35_RS12075	COG0445	tRNA wobble uridine modification
H7F35_RS12080	COG0357	Ribosomal RNA small subunit methyltransferase G
H7F35_RS12090	COG1192	Involved in chromosome partitioning
H7F35_RS12100	COG1475	DNA binding
H7F35_RS12110	COG0277	FAD linked oxidase domain protein
H7F35_RS12120	COG2096	Adenosyltransferase
H7F35_RS12200	COG0583	DNA-binding transcription factor activity
H7F35_RS12220	COG3181	Tripartite tricarboxylate transporter family receptor
H7F35_RS12230	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
H7F35_RS12235	COG2894	cell division
H7F35_RS12240	COG0850	regulation of cytokinetic process
H7F35_RS12245	COG2233	PERMEase
H7F35_RS12255	COG2050	protein possibly involved in aromatic compounds catabolism
H7F35_RS12280	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H7F35_RS12285	COG0318	PFAM AMP-dependent synthetase and ligase
H7F35_RS12290	COG1024	Enoyl-CoA hydratase
H7F35_RS12300	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
H7F35_RS12310	COG0477	Major facilitator Superfamily
H7F35_RS12325	COG1250	3-hydroxyacyl-CoA dehydrogenase
H7F35_RS12335	COG3246	L-lysine catabolic process to acetate
H7F35_RS12360	COG3284	Transcriptional regulator
H7F35_RS12395	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H7F35_RS12415	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
H7F35_RS12445	COG1959	2 iron, 2 sulfur cluster binding
H7F35_RS12465	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
H7F35_RS12470	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H7F35_RS12475	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H7F35_RS12480	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H7F35_RS12480	COG1116	anion transmembrane transporter activity
H7F35_RS12495	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H7F35_RS12505	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
H7F35_RS12560	COG0583	DNA-binding transcription factor activity
H7F35_RS12565	COG1960	acyl-CoA dehydrogenase activity
H7F35_RS12570	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H7F35_RS12585	COG1276	copper resistance
H7F35_RS12595	COG1573	uracil-dna glycosylase
H7F35_RS12615	COG3246	L-lysine catabolic process to acetate
H7F35_RS12625	COG3485	protocatechuate 3,4-dioxygenase
H7F35_RS12675	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H7F35_RS12680	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H7F35_RS12690	COG1129	ABC transporter
H7F35_RS12695	COG0559	Belongs to the binding-protein-dependent transport system permease family
H7F35_RS12725	COG2066	Belongs to the glutaminase family
H7F35_RS12740	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H7F35_RS12750	COG2015	COG2015, Alkyl sulfatase and related hydrolases
H7F35_RS12755	COG0700	Nucleoside recognition
H7F35_RS12760	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H7F35_RS12770	COG1858	cytochrome C peroxidase
H7F35_RS12780	COG0410	ABC transporter
H7F35_RS12800	COG0683	leucine binding
H7F35_RS12805	COG0633	Ferredoxin
H7F35_RS12880	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
H7F35_RS12890	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H7F35_RS12895	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H7F35_RS12920	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H7F35_RS12925	COG1116	anion transmembrane transporter activity
H7F35_RS12935	COG2986	histidine ammonia-lyase
H7F35_RS12940	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
H7F35_RS12955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7F35_RS12960	COG0765	amino acid transport
H7F35_RS12970	COG1228	amidohydrolase
H7F35_RS12975	COG0402	S-adenosylhomocysteine deaminase activity
H7F35_RS12985	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
H7F35_RS13015	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
H7F35_RS13020	COG1410	methionine synthase
H7F35_RS13020	COG0646	methionine synthase
H7F35_RS13045	COG1309	transcriptional regulator
H7F35_RS13075	COG0683	leucine binding
H7F35_RS13095	COG1335	isochorismatase
H7F35_RS13105	COG2080	2 iron, 2 sulfur cluster binding
H7F35_RS13110	COG1529	Aldehyde oxidase and xanthine dehydrogenase
H7F35_RS13110	COG2010	Cytochrome c
H7F35_RS13125	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
H7F35_RS13170	COG0347	Belongs to the P(II) protein family
H7F35_RS13175	COG0004	ammonium transporteR
H7F35_RS13185	COG0583	DNA-binding transcription factor activity
H7F35_RS13190	COG0277	FAD linked oxidase domain protein
H7F35_RS13195	COG0277	FAD linked oxidase domain protein
H7F35_RS13200	COG0247	lactate metabolic process
H7F35_RS13210	COG0386	Belongs to the glutathione peroxidase family
H7F35_RS13220	COG0477	Major facilitator Superfamily
H7F35_RS13225	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H7F35_RS13255	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
H7F35_RS13270	COG0129	dihydroxy-acid dehydratase activity
H7F35_RS13285	COG3971	2-oxopent-4-enoate hydratase activity
H7F35_RS13310	COG1012	belongs to the aldehyde dehydrogenase family
H7F35_RS13325	COG1846	Transcriptional regulator
H7F35_RS13335	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H7F35_RS13355	COG0583	DNA-binding transcription factor activity
H7F35_RS13365	COG1473	amidohydrolase
H7F35_RS13370	COG2974	May be involved in recombination
H7F35_RS13395	COG2205	protein histidine kinase activity
H7F35_RS13400	COG0745	RESPONSE REGULATOR receiver
H7F35_RS13415	COG2211	Major facilitator Superfamily
H7F35_RS13420	COG0501	Belongs to the peptidase M48B family
H7F35_RS13430	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H7F35_RS13435	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H7F35_RS13460	COG1079	Belongs to the binding-protein-dependent transport system permease family
H7F35_RS13465	COG1335	isochorismatase
H7F35_RS13470	COG3845	ABC transporter
H7F35_RS13495	COG0583	DNA-binding transcription factor activity
H7F35_RS13515	COG0708	Exodeoxyribonuclease III
H7F35_RS13520	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
H7F35_RS13530	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H7F35_RS13535	COG0154	amidase activity
H7F35_RS13540	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H7F35_RS13545	COG1077	Cell shape determining protein MreB Mrl
H7F35_RS13550	COG1792	Involved in formation and maintenance of cell shape
H7F35_RS13560	COG0768	penicillin binding
H7F35_RS13565	COG0179	Fumarylacetoacetate (FAA) hydrolase
H7F35_RS13575	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
H7F35_RS13585	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H7F35_RS13600	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
H7F35_RS13625	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H7F35_RS13630	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
H7F35_RS13665	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H7F35_RS13680	COG1177	transmembrane transport
H7F35_RS13685	COG1176	ABC-type spermidine putrescine transport system, permease component I
H7F35_RS13690	COG3842	ATPase activity
H7F35_RS13710	COG1012	belongs to the aldehyde dehydrogenase family
H7F35_RS13720	COG0436	Aminotransferase
H7F35_RS13725	COG0028	Belongs to the TPP enzyme family
H7F35_RS13735	COG0004	ammonium transporteR
H7F35_RS13755	COG0724	RNA recognition motif
H7F35_RS13765	COG0023	Translation Initiation Factor
H7F35_RS13770	COG0513	Belongs to the DEAD box helicase family
H7F35_RS13780	COG0330	HflC and HflK could
H7F35_RS13785	COG1960	acyl-CoA dehydrogenase activity
H7F35_RS13790	COG1960	acyl-CoA dehydrogenase activity
H7F35_RS13805	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H7F35_RS13820	COG2733	membrane
H7F35_RS13830	COG0584	glycerophosphoryl diester phosphodiesterase
H7F35_RS13835	COG0583	DNA-binding transcription factor activity
H7F35_RS13840	COG2233	PERMEase
H7F35_RS13850	COG1473	amidohydrolase
H7F35_RS13860	COG0243	molybdopterin cofactor binding
H7F35_RS13875	COG1028	Short-chain dehydrogenase reductase Sdr
H7F35_RS13880	COG1070	Carbohydrate kinase
H7F35_RS13885	COG1063	alcohol dehydrogenase
H7F35_RS13890	COG1172	Belongs to the binding-protein-dependent transport system permease family
H7F35_RS13900	COG1879	ABC-type sugar transport system periplasmic component
H7F35_RS13905	COG4977	sequence-specific DNA binding
H7F35_RS13910	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H7F35_RS13940	COG0583	DNA-binding transcription factor activity
H7F35_RS13955	COG2271	Major facilitator Superfamily
H7F35_RS13960	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H7F35_RS13970	COG3181	Tripartite tricarboxylate transporter family receptor
H7F35_RS13975	COG0446	pyridine nucleotide-disulphide oxidoreductase
H7F35_RS13985	COG1946	Acyl-CoA thioesterase
H7F35_RS13995	COG1028	Short-chain dehydrogenase reductase Sdr
H7F35_RS14005	COG0559	Belongs to the binding-protein-dependent transport system permease family
H7F35_RS14010	COG4177	L-phenylalanine transmembrane transporter activity
H7F35_RS14025	COG1028	Short-chain dehydrogenase reductase Sdr
H7F35_RS14030	COG1028	Short-chain dehydrogenase reductase Sdr
H7F35_RS14035	COG1053	succinate dehydrogenase
H7F35_RS14045	COG1028	Short-chain dehydrogenase reductase Sdr
H7F35_RS14050	COG0659	secondary active sulfate transmembrane transporter activity
H7F35_RS14055	COG1129	ABC transporter
H7F35_RS14100	COG0667	Aldo Keto reductase
H7F35_RS14105	COG1172	Belongs to the binding-protein-dependent transport system permease family
H7F35_RS14120	COG1070	Carbohydrate kinase
H7F35_RS14125	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
H7F35_RS14130	COG2188	Transcriptional regulator
H7F35_RS14150	COG0629	single-stranded DNA binding
H7F35_RS14240	COG4948	Mandelate Racemase Muconate Lactonizing
H7F35_RS14245	COG1028	Short-chain dehydrogenase reductase Sdr
H7F35_RS14255	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H7F35_RS14260	COG0583	DNA-binding transcription factor activity
H7F35_RS14265	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H7F35_RS14270	COG0436	Aminotransferase
H7F35_RS14280	COG0511	ligase activity, forming carbon-carbon bonds
H7F35_RS14290	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
H7F35_RS14295	COG1984	allophanate hydrolase subunit 2
H7F35_RS14305	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
H7F35_RS14310	COG4221	oxidoreductase activity
H7F35_RS14315	COG0765	amino acid transport
H7F35_RS14320	COG0765	amino acid transport
H7F35_RS14335	COG0154	amidase activity
H7F35_RS14375	COG0583	DNA-binding transcription factor activity
H7F35_RS14380	COG1595	DNA-templated transcription, initiation
H7F35_RS14385	COG3712	iron ion homeostasis
H7F35_RS14390	COG4774	siderophore transport
H7F35_RS14405	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H7F35_RS14410	COG0390	transport system, permease component
H7F35_RS14420	COG0217	transcriptional regulatory protein
H7F35_RS14445	COG0583	DNA-binding transcription factor activity
H7F35_RS14450	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
H7F35_RS14465	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
H7F35_RS14470	COG1122	ATPase activity
H7F35_RS14480	COG1268	BioY protein
H7F35_RS14495	COG1335	isochorismatase
H7F35_RS14525	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H7F35_RS14530	COG0318	PFAM AMP-dependent synthetase and ligase
H7F35_RS14535	COG0482	sulfurtransferase activity
H7F35_RS14550	COG0745	RESPONSE REGULATOR receiver
H7F35_RS14570	COG0318	PFAM AMP-dependent synthetase and ligase
H7F35_RS14575	COG0601	transmembrane transport
H7F35_RS14580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H7F35_RS14585	COG0444	Belongs to the ABC transporter superfamily
H7F35_RS14590	COG4608	Belongs to the ABC transporter superfamily
H7F35_RS14595	COG0747	negative chemotaxis
H7F35_RS14600	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
H7F35_RS14605	COG0598	Magnesium transport protein CorA
H7F35_RS14615	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
H7F35_RS14625	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
H7F35_RS14630	COG0735	belongs to the Fur family
H7F35_RS14635	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H7F35_RS14640	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
H7F35_RS14655	COG0058	SHG alpha-glucan phosphorylase activity
H7F35_RS14660	COG0297	glycogen (starch) synthase activity
H7F35_RS14665	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
H7F35_RS14670	COG1523	belongs to the glycosyl hydrolase 13 family
H7F35_RS14675	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
H7F35_RS14680	COG0366	Alpha amylase catalytic
H7F35_RS14685	COG2072	flavoprotein involved in K transport
H7F35_RS14710	COG0495	leucyl-tRNA aminoacylation
H7F35_RS14725	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
H7F35_RS14735	COG3158	transport of potassium into the cell
H7F35_RS14740	COG3135	benzoate transporter
H7F35_RS14745	COG0189	ligase activity
H7F35_RS14755	COG0121	glutamine amidotransferase
H7F35_RS14765	COG2814	Major facilitator Superfamily
H7F35_RS14780	COG0205	6-phosphofructokinase activity
H7F35_RS14790	COG1024	Enoyl-CoA hydratase
H7F35_RS14795	COG0183	Belongs to the thiolase family
H7F35_RS14805	COG0583	DNA-binding transcription factor activity
H7F35_RS14810	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
H7F35_RS14835	COG4804	nuclease activity
H7F35_RS14845	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
H7F35_RS14850	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
H7F35_RS14855	COG3181	Tripartite tricarboxylate transporter family receptor
H7F35_RS14860	COG1414	Transcriptional regulator
H7F35_RS14865	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H7F35_RS14870	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H7F35_RS14895	COG0018	arginyl-trna synthetase
H7F35_RS14910	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
H7F35_RS14915	COG1137	ATPase activity
H7F35_RS14920	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
H7F35_RS14925	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H7F35_RS14980	COG0069	glutamate synthase activity
H7F35_RS14985	COG0653	protein targeting
H7F35_RS15050	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
H7F35_RS15065	COG2967	ApaG domain
H7F35_RS15075	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H7F35_RS15130	COG2831	hemolysin activation secretion protein
H7F35_RS15140	COG1335	isochorismatase
H7F35_RS15145	COG4977	sequence-specific DNA binding
H7F35_RS15150	COG4251	negative regulation of phosphorylation
H7F35_RS15165	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
H7F35_RS15170	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
H7F35_RS15195	COG0515	serine threonine protein kinase
H7F35_RS15330	COG4774	siderophore transport
H7F35_RS15340	COG1595	DNA-templated transcription, initiation
H7F35_RS15360	COG0546	phosphoglycolate phosphatase activity
H7F35_RS15390	COG1280	lysine exporter protein (LysE YggA)
H7F35_RS15395	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H7F35_RS15400	COG0134	indole-3-glycerol-phosphate synthase activity
H7F35_RS15405	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
H7F35_RS15425	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
H7F35_RS15445	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
H7F35_RS15450	COG0081	regulation of translation
H7F35_RS15455	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
H7F35_RS15460	COG0222	ribosome binding
H7F35_RS15465	COG0085	RNA polymerase activity
H7F35_RS15470	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
H7F35_RS15490	COG5000	phosphorelay sensor kinase activity
H7F35_RS15495	COG2204	response regulator
H7F35_RS15515	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
H7F35_RS15530	COG0210	DNA helicase
H7F35_RS15535	COG0679	Auxin Efflux Carrier
H7F35_RS15555	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H7F35_RS15560	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
H7F35_RS15605	COG1129	ABC transporter
H7F35_RS15610	COG1129	ABC transporter
H7F35_RS15620	COG0384	phenazine biosynthesis protein PhzF
H7F35_RS15625	COG0583	DNA-binding transcription factor activity
H7F35_RS15630	COG4977	sequence-specific DNA binding
H7F35_RS15630	COG1917	Cupin 2, conserved barrel domain protein
H7F35_RS15650	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H7F35_RS15655	COG4232	protein-disulfide reductase activity
H7F35_RS15660	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
H7F35_RS15670	COG1609	Transcriptional regulator
H7F35_RS15710	COG0583	DNA-binding transcription factor activity
H7F35_RS15725	COG1028	Short-chain dehydrogenase reductase Sdr
H7F35_RS15735	COG1215	transferase activity, transferring glycosyl groups
H7F35_RS15740	COG0726	polysaccharide deacetylase
H7F35_RS15740	COG1649	PFAM Uncharacterised BCR, COG1649
H7F35_RS15755	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H7F35_RS15760	COG1280	lysine exporter protein (LysE YggA)
H7F35_RS15770	COG0384	phenazine biosynthesis protein PhzF
H7F35_RS15775	COG0625	glutathione transferase activity
H7F35_RS15780	COG0384	phenazine biosynthesis protein PhzF
H7F35_RS15785	COG1280	lysine exporter protein (LysE YggA)
H7F35_RS15790	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H7F35_RS15800	COG0697	spore germination
H7F35_RS15810	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H7F35_RS15825	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H7F35_RS15880	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H7F35_RS15885	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H7F35_RS15890	COG0318	PFAM AMP-dependent synthetase and ligase
H7F35_RS15920	COG0438	transferase activity, transferring glycosyl groups
H7F35_RS15920	COG1216	Glycosyl transferase, family 2
H7F35_RS15945	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
H7F35_RS15950	COG4106	trans-aconitate 2-methyltransferase activity
H7F35_RS15970	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H7F35_RS15975	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
H7F35_RS15980	COG1216	Glycosyl transferase, family 2
H7F35_RS15980	COG0438	transferase activity, transferring glycosyl groups
H7F35_RS16000	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
H7F35_RS16000	COG0662	Cupin 2, conserved barrel domain protein
H7F35_RS16005	COG1216	Glycosyl transferase, family 2
H7F35_RS16005	COG0438	transferase activity, transferring glycosyl groups
H7F35_RS16010	COG0438	transferase activity, transferring glycosyl groups
H7F35_RS16010	COG1216	Glycosyl transferase, family 2
H7F35_RS16020	COG1216	Glycosyl transferase, family 2
H7F35_RS16020	COG0463	Glycosyl transferase, family 2
H7F35_RS16025	COG2755	lipolytic protein G-D-S-L family
H7F35_RS16025	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
H7F35_RS16040	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
H7F35_RS16050	COG0753	catalase activity
H7F35_RS16055	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
H7F35_RS16065	COG2721	sulfolactate sulfo-lyase activity
H7F35_RS16075	COG1028	Short-chain dehydrogenase reductase Sdr
H7F35_RS16080	COG1028	Short-chain dehydrogenase reductase Sdr
H7F35_RS16085	COG0179	Fumarylacetoacetate (FAA) hydrolase
H7F35_RS16090	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
H7F35_RS16105	COG4221	oxidoreductase activity
H7F35_RS16115	COG1960	acyl-CoA dehydrogenase activity
H7F35_RS16125	COG1024	Enoyl-CoA hydratase
H7F35_RS16125	COG1250	3-hydroxyacyl-CoA dehydrogenase
H7F35_RS16130	COG2852	Protein conserved in bacteria
H7F35_RS16135	COG0183	Belongs to the thiolase family
H7F35_RS16160	COG1024	Enoyl-CoA hydratase
H7F35_RS16165	COG0683	leucine binding
H7F35_RS16170	COG1607	acyl-coa hydrolase
H7F35_RS16175	COG5265	(ABC) transporter
H7F35_RS16180	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H7F35_RS16185	COG0154	amidase activity
H7F35_RS16190	COG0583	DNA-binding transcription factor activity
H7F35_RS16195	COG1027	Aspartate ammonia-lyase
H7F35_RS16200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7F35_RS16205	COG0765	amino acid transport
H7F35_RS16210	COG0765	amino acid transport
H7F35_RS16215	COG1126	abc transporter atp-binding protein
H7F35_RS16250	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
H7F35_RS16255	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
H7F35_RS16255	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
H7F35_RS16260	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
H7F35_RS16285	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
H7F35_RS16310	COG0318	PFAM AMP-dependent synthetase and ligase
H7F35_RS16320	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H7F35_RS16325	COG1024	Enoyl-CoA hydratase
H7F35_RS16330	COG1960	acyl-CoA dehydrogenase activity
H7F35_RS16335	COG1960	acyl-CoA dehydrogenase activity
H7F35_RS16340	COG0183	Belongs to the thiolase family
H7F35_RS16345	COG1250	3-hydroxyacyl-CoA dehydrogenase
H7F35_RS16345	COG1024	Enoyl-CoA hydratase
H7F35_RS16350	COG0583	DNA-binding transcription factor activity
H7F35_RS16365	COG1881	PFAM PEBP family protein
H7F35_RS16390	COG1595	DNA-templated transcription, initiation
H7F35_RS16395	COG0418	dihydroorotase activity
H7F35_RS16415	COG0501	Belongs to the peptidase M48B family
H7F35_RS16425	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H7F35_RS16440	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
H7F35_RS16450	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
H7F35_RS16490	COG1566	PFAM secretion protein HlyD family protein
H7F35_RS16500	COG2814	Major facilitator Superfamily
H7F35_RS16520	COG1187	pseudouridine synthase activity
H7F35_RS16570	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H7F35_RS16580	COG2807	transmembrane transport
H7F35_RS16585	COG0590	tRNA wobble adenosine to inosine editing
H7F35_RS16610	COG1942	4-Oxalocrotonate Tautomerase
H7F35_RS16640	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H7F35_RS16655	COG2814	Major facilitator Superfamily
H7F35_RS16665	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H7F35_RS16700	COG0583	DNA-binding transcription factor activity
H7F35_RS16705	COG1335	isochorismatase
H7F35_RS16715	COG0402	S-adenosylhomocysteine deaminase activity
H7F35_RS16735	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
H7F35_RS16750	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
H7F35_RS16755	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
H7F35_RS16760	COG0523	cobalamin synthesis protein
H7F35_RS16780	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
H7F35_RS16785	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
H7F35_RS16790	COG2001	Belongs to the MraZ family
H7F35_RS16795	COG0275	rRNA processing
H7F35_RS16810	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H7F35_RS16815	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H7F35_RS16820	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
H7F35_RS16825	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
H7F35_RS16830	COG0772	Belongs to the SEDS family
H7F35_RS16835	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
H7F35_RS16840	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H7F35_RS16845	COG1181	Belongs to the D-alanine--D-alanine ligase family
H7F35_RS16850	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
H7F35_RS16865	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
H7F35_RS16880	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
H7F35_RS16885	COG0575	Belongs to the CDS family
H7F35_RS16900	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H7F35_RS16905	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
H7F35_RS16920	COG3150	esterase
H7F35_RS16925	COG2197	response regulator
H7F35_RS16940	COG0772	Belongs to the SEDS family
H7F35_RS16945	COG0312	modulator of DNA gyrase
H7F35_RS16955	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H7F35_RS16965	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H7F35_RS16975	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H7F35_RS16980	COG0511	ligase activity, forming carbon-carbon bonds
H7F35_RS16985	COG0439	Biotin carboxylase
H7F35_RS16990	COG2264	protein methyltransferase activity
H7F35_RS17000	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H7F35_RS17010	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H7F35_RS17040	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
H7F35_RS17045	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H7F35_RS17075	COG3416	Protein conserved in bacteria
H7F35_RS17075	COG2943	transferase activity, transferring hexosyl groups
H7F35_RS17080	COG2204	response regulator
H7F35_RS17090	COG2205	protein histidine kinase activity
H7F35_RS17095	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
H7F35_RS17105	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H7F35_RS17110	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H7F35_RS17145	COG0037	tRNA processing
H7F35_RS17155	COG2814	Major facilitator Superfamily
H7F35_RS17165	COG1028	Short-chain dehydrogenase reductase Sdr
H7F35_RS17175	COG2175	clavaminate synthase activity
H7F35_RS17185	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
H7F35_RS17190	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H7F35_RS17220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H7F35_RS17230	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
H7F35_RS17235	COG3387	PFAM Glycoside hydrolase 15-related
H7F35_RS17240	COG1877	trehalose-phosphatase activity
H7F35_RS17245	COG0617	tRNA 3'-terminal CCA addition
H7F35_RS17255	COG0625	glutathione transferase activity
H7F35_RS17260	COG1285	pathogenesis
H7F35_RS17265	COG0739	heme binding
H7F35_RS17265	COG0741	lytic transglycosylase activity
H7F35_RS17265	COG1196	nuclear chromosome segregation
H7F35_RS17270	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
H7F35_RS17275	COG0583	DNA-binding transcription factor activity
H7F35_RS17290	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H7F35_RS17300	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
H7F35_RS17305	COG1522	sequence-specific DNA binding
H7F35_RS17325	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H7F35_RS17340	COG0583	DNA-binding transcription factor activity
H7F35_RS17345	COG0583	DNA-binding transcription factor activity
H7F35_RS17355	COG3181	Tripartite tricarboxylate transporter family receptor
H7F35_RS17390	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
H7F35_RS17430	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H7F35_RS17450	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H7F35_RS17455	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H7F35_RS17460	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H7F35_RS17480	COG0506	proline dehydrogenase activity
H7F35_RS17480	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H7F35_RS17480	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H7F35_RS17505	COG1902	pentaerythritol trinitrate reductase activity
H7F35_RS17510	COG0697	spore germination
H7F35_RS17515	COG0583	DNA-binding transcription factor activity
H7F35_RS17525	COG2885	chlorophyll binding
H7F35_RS17530	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H7F35_RS17545	COG3386	PFAM SMP-30 Gluconolaconase
H7F35_RS17550	COG1028	Short-chain dehydrogenase reductase Sdr
H7F35_RS17560	COG1012	belongs to the aldehyde dehydrogenase family
H7F35_RS17565	COG1879	ABC-type sugar transport system periplasmic component
H7F35_RS17570	COG4213	ABC transporter substrate-binding protein
H7F35_RS17580	COG4214	carbohydrate transport
H7F35_RS17585	COG1129	ABC transporter
H7F35_RS17590	COG1172	Belongs to the binding-protein-dependent transport system permease family
H7F35_RS17595	COG1172	Belongs to the binding-protein-dependent transport system permease family
H7F35_RS17625	COG0189	ligase activity
H7F35_RS17625	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H7F35_RS17630	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H7F35_RS17630	COG0189	ligase activity
H7F35_RS17635	COG1132	(ABC) transporter
H7F35_RS17650	COG1785	Belongs to the alkaline phosphatase family
H7F35_RS17655	COG1785	Belongs to the alkaline phosphatase family
H7F35_RS17670	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
H7F35_RS17675	COG4178	(ABC) transporter
H7F35_RS17685	COG1840	ABC-type Fe3 transport system, periplasmic component
H7F35_RS17690	COG3842	ATPase activity
H7F35_RS17695	COG4149	molybdate abc transporter
H7F35_RS17705	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H7F35_RS17710	COG3181	Tripartite tricarboxylate transporter family receptor
H7F35_RS17725	COG2828	Protein conserved in bacteria
H7F35_RS17740	COG0066	3-isopropylmalate dehydratase activity
H7F35_RS17745	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
H7F35_RS17755	COG2186	Transcriptional regulator
H7F35_RS17775	COG2171	N-acyltransferase activity
H7F35_RS17780	COG2271	Major facilitator Superfamily
H7F35_RS17785	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H7F35_RS17795	COG2863	cytochrome
H7F35_RS17805	COG0753	catalase activity
H7F35_RS17825	COG3511	phospholipase C
H7F35_RS17895	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H7F35_RS17910	COG1765	OsmC-like protein
H7F35_RS17915	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
H7F35_RS17930	COG1473	amidohydrolase
H7F35_RS17940	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H7F35_RS17945	COG0444	Belongs to the ABC transporter superfamily
H7F35_RS17950	COG4608	Belongs to the ABC transporter superfamily
H7F35_RS17965	COG3384	dioxygenase
H7F35_RS17970	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
H7F35_RS17975	COG1840	ABC-type Fe3 transport system, periplasmic component
H7F35_RS18005	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H7F35_RS18010	COG0166	Belongs to the GPI family
H7F35_RS18035	COG1175	transmembrane transport
H7F35_RS18040	COG0395	ABC-type sugar transport system, permease component
H7F35_RS18045	COG3842	ATPase activity
H7F35_RS18050	COG0246	Mannitol dehydrogenase
H7F35_RS18060	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H7F35_RS18070	COG2207	Transcriptional regulator
H7F35_RS18070	COG4753	response regulator
H7F35_RS18075	COG1070	Carbohydrate kinase
H7F35_RS18080	COG0459	protein refolding
H7F35_RS18085	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
H7F35_RS18105	COG4580	involved in the transport of maltose and maltodextrins
H7F35_RS18110	COG1609	Transcriptional regulator
H7F35_RS18115	COG3537	Alpha-1,2-mannosidase
H7F35_RS18120	COG3537	Alpha-1,2-mannosidase
H7F35_RS18130	COG0583	DNA-binding transcription factor activity
H7F35_RS18135	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H7F35_RS18155	COG4772	TonB-dependent receptor
H7F35_RS18160	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H7F35_RS18185	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
H7F35_RS18195	COG1560	Kdo2-lipid A biosynthetic process
H7F35_RS18205	COG0218	Necessary for normal cell division and for the maintenance of normal septation
H7F35_RS18215	COG1333	cytochrome c biogenesis protein
H7F35_RS18220	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
H7F35_RS18225	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
H7F35_RS18230	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
H7F35_RS18235	COG0019	diaminopimelate decarboxylase activity
H7F35_RS18240	COG1965	Belongs to the frataxin family
H7F35_RS18275	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
H7F35_RS18280	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
H7F35_RS18285	COG0232	Belongs to the dGTPase family. Type 2 subfamily
H7F35_RS18315	COG0070	glutamate synthase
H7F35_RS18315	COG0069	glutamate synthase activity
H7F35_RS18315	COG0067	glutamate synthase
H7F35_RS18325	COG1127	ABC transporter
H7F35_RS18330	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
H7F35_RS18335	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
H7F35_RS18340	COG2853	Lipoprotein
H7F35_RS18355	COG1131	(ABC) transporter
H7F35_RS18360	COG0842	Transport permease protein
H7F35_RS18365	COG5007	Belongs to the BolA IbaG family
H7F35_RS18370	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
H7F35_RS18375	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
H7F35_RS18395	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
H7F35_RS18400	COG0131	Imidazoleglycerol-phosphate dehydratase
H7F35_RS18410	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
H7F35_RS18425	COG1301	dicarboxylic acid transport
H7F35_RS18435	COG0107	imidazoleglycerol-phosphate synthase activity
H7F35_RS18440	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
H7F35_RS18445	COG0140	phosphoribosyl-ATP diphosphatase activity
H7F35_RS18455	COG0537	adenosine 5'-monophosphoramidase activity
H7F35_RS18460	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
H7F35_RS18465	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
H7F35_RS18470	COG0805	protein transport
H7F35_RS18480	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
H7F35_RS18485	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
H7F35_RS18490	COG1970	mechanosensitive ion channel activity
H7F35_RS18510	COG0723	plastoquinol--plastocyanin reductase activity
H7F35_RS18515	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
H7F35_RS18520	COG2857	Cytochrome c1
H7F35_RS18525	COG0625	glutathione transferase activity
H7F35_RS18530	COG2969	positive regulation of protein catabolic process
H7F35_RS18540	COG2755	lipolytic protein G-D-S-L family
H7F35_RS18540	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
H7F35_RS18545	COG4715	Zinc finger, swim domain protein
H7F35_RS18550	COG3552	Protein containing von Willebrand factor type A (VWA) domain
H7F35_RS18555	COG2425	protein containing a von Willebrand factor type A (vWA) domain
H7F35_RS18560	COG0714	Associated with various cellular activities
H7F35_RS18570	COG3831	ATPase activity
H7F35_RS18580	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
H7F35_RS18590	COG4591	ABC-type transport system involved in lipoprotein release permease component
H7F35_RS18595	COG1136	(ABC) transporter
H7F35_RS18605	COG1595	DNA-templated transcription, initiation
H7F35_RS18610	COG0740	serine-type endopeptidase activity
H7F35_RS18615	COG0251	oxidation-reduction process
H7F35_RS18630	COG0601	transmembrane transport
H7F35_RS18660	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
H7F35_RS18695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7F35_RS18725	COG1012	belongs to the aldehyde dehydrogenase family
H7F35_RS18770	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
H7F35_RS18790	COG1253	flavin adenine dinucleotide binding
H7F35_RS18795	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H7F35_RS18810	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
H7F35_RS18815	COG0463	Glycosyl transferase, family 2
H7F35_RS18820	COG0671	phosphoesterase, PA-phosphatase related
H7F35_RS18835	COG1028	Short-chain dehydrogenase reductase Sdr
H7F35_RS18840	COG2030	dehydratase
H7F35_RS18840	COG1012	belongs to the aldehyde dehydrogenase family
H7F35_RS18865	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H7F35_RS18870	COG2151	metal-sulfur cluster biosynthetic enzyme
H7F35_RS18875	COG3396	Phenylacetate-CoA oxygenase
H7F35_RS18880	COG3460	Phenylacetate-CoA oxygenase
H7F35_RS18885	COG3396	Phenylacetate-CoA oxygenase
H7F35_RS18895	COG2050	protein possibly involved in aromatic compounds catabolism
H7F35_RS18900	COG1024	Enoyl-CoA hydratase
H7F35_RS18910	COG1309	transcriptional regulator
H7F35_RS18935	COG0714	Associated with various cellular activities
H7F35_RS18940	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H7F35_RS18945	COG0084	hydrolase, TatD family'
H7F35_RS18960	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
H7F35_RS18965	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H7F35_RS18985	COG1960	acyl-CoA dehydrogenase activity
H7F35_RS18990	COG0318	PFAM AMP-dependent synthetase and ligase
H7F35_RS19000	COG3181	Tripartite tricarboxylate transporter family receptor
H7F35_RS19035	COG0583	DNA-binding transcription factor activity
H7F35_RS19045	COG1283	sodium-dependent phosphate transmembrane transporter activity
H7F35_RS19050	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H7F35_RS19075	COG1609	Transcriptional regulator
H7F35_RS19080	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
H7F35_RS19090	COG0196	riboflavin kinase activity
H7F35_RS19100	COG1024	Enoyl-CoA hydratase
H7F35_RS19115	COG1960	acyl-CoA dehydrogenase activity
H7F35_RS19120	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
H7F35_RS19140	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
H7F35_RS19140	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
H7F35_RS19150	COG0267	Belongs to the bacterial ribosomal protein bL33 family
H7F35_RS19155	COG0227	Belongs to the bacterial ribosomal protein bL28 family
H7F35_RS19160	COG0492	ferredoxin-NADP+ reductase activity
H7F35_RS19170	COG1674	ftsk spoiiie
H7F35_RS19175	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
H7F35_RS19180	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H7F35_RS19185	COG0559	Belongs to the binding-protein-dependent transport system permease family
H7F35_RS19220	COG0500	methyltransferase
H7F35_RS19235	COG2816	NAD+ diphosphatase activity
H7F35_RS19240	COG0425	Belongs to the sulfur carrier protein TusA family
H7F35_RS19250	COG0525	valine-tRNA ligase activity
H7F35_RS19255	COG3022	response to hydroperoxide
H7F35_RS19270	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
H7F35_RS19270	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
H7F35_RS19275	COG1028	Short-chain dehydrogenase reductase Sdr
H7F35_RS19290	COG4948	Mandelate Racemase Muconate Lactonizing
H7F35_RS19295	COG3181	Tripartite tricarboxylate transporter family receptor
H7F35_RS19310	COG1960	acyl-CoA dehydrogenase activity
H7F35_RS19320	COG1960	acyl-CoA dehydrogenase activity
H7F35_RS19330	COG0318	PFAM AMP-dependent synthetase and ligase
H7F35_RS19355	COG0540	Belongs to the ATCase OTCase family
H7F35_RS19365	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H7F35_RS19370	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
H7F35_RS19395	COG0583	DNA-binding transcription factor activity
H7F35_RS19400	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
H7F35_RS19420	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
H7F35_RS19440	COG1172	Belongs to the binding-protein-dependent transport system permease family
H7F35_RS19450	COG4948	Mandelate Racemase Muconate Lactonizing
H7F35_RS19455	COG1028	Short-chain dehydrogenase reductase Sdr
H7F35_RS19480	COG0477	Major facilitator Superfamily
H7F35_RS19485	COG1304	FMN binding
H7F35_RS19490	COG0583	DNA-binding transcription factor activity
H7F35_RS19505	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
H7F35_RS19510	COG4221	oxidoreductase activity
H7F35_RS19545	COG0747	negative chemotaxis
H7F35_RS19550	COG0601	transmembrane transport
H7F35_RS19560	COG4172	Belongs to the ABC transporter superfamily
H7F35_RS19570	COG1473	amidohydrolase
H7F35_RS19575	COG2807	transmembrane transport
H7F35_RS19580	COG2186	Transcriptional regulator
H7F35_RS19585	COG0583	DNA-binding transcription factor activity
H7F35_RS19610	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
H7F35_RS19700	COG0346	lactoylglutathione lyase activity
H7F35_RS19750	COG3210	domain, Protein
H7F35_RS19765	COG2831	hemolysin activation secretion protein
H7F35_RS19775	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H7F35_RS19780	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H7F35_RS19795	COG0165	Argininosuccinate lyase
H7F35_RS19800	COG3275	phosphorelay sensor kinase activity
H7F35_RS19830	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H7F35_RS19850	COG0583	DNA-binding transcription factor activity
H7F35_RS19865	COG3459	Glycosyltransferase 36 associated
H7F35_RS19875	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
H7F35_RS19880	COG0181	hydroxymethylbilane synthase activity
H7F35_RS19905	COG0583	DNA-binding transcription factor activity
H7F35_RS19910	COG1530	ribonuclease E activity
H7F35_RS19930	COG0616	signal peptide processing
H7F35_RS19930	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
H7F35_RS19935	COG2223	nitrite transmembrane transporter activity
H7F35_RS19940	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
H7F35_RS19945	COG0424	maF-like protein
H7F35_RS19950	COG1399	metal-binding, possibly nucleic acid-binding protein
H7F35_RS19955	COG0333	Belongs to the bacterial ribosomal protein bL32 family
H7F35_RS19960	COG0416	fatty acid biosynthetic process
H7F35_RS19965	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H7F35_RS19975	COG1028	Short-chain dehydrogenase reductase Sdr
H7F35_RS19980	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H7F35_RS19985	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H7F35_RS20010	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H7F35_RS20015	COG0481	GTPase activity
H7F35_RS20020	COG0681	Belongs to the peptidase S26 family
H7F35_RS20030	COG0571	ribonuclease III activity
H7F35_RS20035	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
H7F35_RS20040	COG1381	Involved in DNA repair and RecF pathway recombination
H7F35_RS20045	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
H7F35_RS20050	COG0736	holo-[acyl-carrier-protein] synthase activity
H7F35_RS20055	COG1472	Belongs to the glycosyl hydrolase 3 family
H7F35_RS20070	COG1451	nucleotide metabolic process
H7F35_RS20075	COG0443	Heat shock 70 kDa protein
H7F35_RS20080	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
H7F35_RS20090	COG0762	integral membrane protein
H7F35_RS20095	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
H7F35_RS20100	COG0159	tryptophan synthase activity
H7F35_RS20105	COG0133	tryptophan synthase activity
H7F35_RS20110	COG0135	phosphoribosylanthranilate isomerase activity
H7F35_RS20115	COG0101	tRNA pseudouridine synthase activity
H7F35_RS20125	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
H7F35_RS20130	COG0473	3-isopropylmalate dehydrogenase activity
H7F35_RS20135	COG0066	3-isopropylmalate dehydratase activity
H7F35_RS20140	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
H7F35_RS20155	COG0372	Belongs to the citrate synthase family
H7F35_RS20160	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
H7F35_RS20165	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
H7F35_RS20170	COG1053	succinate dehydrogenase
H7F35_RS20185	COG2188	Transcriptional regulator
H7F35_RS20190	COG0039	L-malate dehydrogenase activity
H7F35_RS20195	COG4106	trans-aconitate 2-methyltransferase activity
H7F35_RS20225	COG5295	Hep Hag repeat protein
H7F35_RS20260	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
H7F35_RS20275	COG0672	)-iron permease
H7F35_RS20280	COG2822	iron ion transport
H7F35_RS20285	COG2837	iron assimilation
H7F35_RS20290	COG2822	iron ion transport
H7F35_RS20310	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H7F35_RS20325	COG3483	tryptophan 2,3-dioxygenase activity
H7F35_RS20335	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
H7F35_RS20340	COG0727	PFAM Uncharacterised protein family (UPF0153)
H7F35_RS20350	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
H7F35_RS20355	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H7F35_RS20365	COG0268	Binds directly to 16S ribosomal RNA
H7F35_RS20370	COG0728	peptidoglycan biosynthetic process
H7F35_RS20385	COG3795	YCII-related domain
H7F35_RS20390	COG3795	YCII-related domain
H7F35_RS20395	COG4941	Belongs to the sigma-70 factor family
H7F35_RS20405	COG1917	Cupin 2, conserved barrel domain protein
H7F35_RS20405	COG4977	sequence-specific DNA binding
H7F35_RS20425	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
H7F35_RS20430	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
H7F35_RS20435	COG0617	tRNA 3'-terminal CCA addition
H7F35_RS20450	COG1392	Phosphate transport regulator
H7F35_RS20455	COG0306	phosphate transporter
H7F35_RS20470	COG0228	four-way junction DNA binding
H7F35_RS20475	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
H7F35_RS20480	COG0336	Belongs to the RNA methyltransferase TrmD family
H7F35_RS20485	COG0335	large ribosomal subunit rRNA binding
H7F35_RS20495	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
H7F35_RS20500	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
H7F35_RS20510	COG1162	GTPase activity
H7F35_RS20515	COG2154	pterin-4-alpha-carbinolamine dehydratase
H7F35_RS20525	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
H7F35_RS20530	COG0513	Belongs to the DEAD box helicase family
H7F35_RS20540	COG1250	3-hydroxyacyl-CoA dehydrogenase
H7F35_RS20545	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H7F35_RS20550	COG0604	alcohol dehydrogenase
H7F35_RS20600	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
H7F35_RS20605	COG1028	Short-chain dehydrogenase reductase Sdr
H7F35_RS20625	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
H7F35_RS20710	COG0154	amidase activity
H7F35_RS20725	COG1028	Short-chain dehydrogenase reductase Sdr
H7F35_RS20740	COG0516	GMP reductase activity
H7F35_RS20745	COG0210	DNA helicase
H7F35_RS20765	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H7F35_RS20795	COG4774	siderophore transport
H7F35_RS20820	COG0412	Dienelactone hydrolase
H7F35_RS20835	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H7F35_RS20840	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
H7F35_RS20845	COG4608	Belongs to the ABC transporter superfamily
H7F35_RS20850	COG0444	Belongs to the ABC transporter superfamily
H7F35_RS20855	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H7F35_RS20860	COG0601	transmembrane transport
H7F35_RS20865	COG0747	negative chemotaxis
H7F35_RS20895	COG3064	Membrane
H7F35_RS20905	COG1136	(ABC) transporter
H7F35_RS20905	COG0577	efflux transmembrane transporter activity
H7F35_RS20935	COG1722	exodeoxyribonuclease VII activity
H7F35_RS20940	COG0142	geranyltranstransferase activity
H7F35_RS20945	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
H7F35_RS20955	COG0411	ABC transporter
H7F35_RS20975	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
H7F35_RS20990	COG0820	rRNA (adenine-C2-)-methyltransferase activity
H7F35_RS21000	COG0820	rRNA (adenine-C2-)-methyltransferase activity
H7F35_RS21030	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H7F35_RS21040	COG0583	DNA-binding transcription factor activity
H7F35_RS21050	COG2271	Major facilitator Superfamily
H7F35_RS21060	COG1012	belongs to the aldehyde dehydrogenase family
H7F35_RS21090	COG0559	Belongs to the binding-protein-dependent transport system permease family
H7F35_RS21165	COG3608	succinylglutamate desuccinylase aspartoacylase
H7F35_RS21165	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
H7F35_RS21175	COG2212	antiporter activity
H7F35_RS21185	COG0651	ATP synthesis coupled electron transport
H7F35_RS21190	COG1006	Multisubunit Na H antiporter MnhC subunit
H7F35_RS21195	COG2111	Na H antiporter
H7F35_RS21195	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H7F35_RS21200	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
H7F35_RS21215	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
H7F35_RS21250	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
H7F35_RS21270	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
H7F35_RS21275	COG0287	Prephenate dehydrogenase
H7F35_RS21280	COG1605	Chorismate mutase
H7F35_RS21280	COG0077	Prephenate dehydratase
H7F35_RS21285	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
H7F35_RS21305	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H7F35_RS21320	COG0582	viral genome integration into host DNA
H7F35_RS21390	COG4386	tail sheath protein
H7F35_RS21435	COG3299	homolog of phage Mu protein gp47
H7F35_RS21485	COG1598	PFAM Uncharacterised protein family UPF0150
H7F35_RS21490	COG1724	mRNA binding
H7F35_RS21515	COG1881	PFAM PEBP family protein
H7F35_RS21540	COG3468	outer membrane autotransporter barrel domain protein
H7F35_RS21565	COG2186	Transcriptional regulator
H7F35_RS21570	COG0473	3-isopropylmalate dehydrogenase activity
H7F35_RS21570	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H7F35_RS21575	COG0129	dihydroxy-acid dehydratase activity
H7F35_RS21585	COG0765	amino acid transport
H7F35_RS21590	COG0765	amino acid transport
H7F35_RS21805	COG1129	ABC transporter
H7F35_RS21815	COG1172	Belongs to the binding-protein-dependent transport system permease family
H7F35_RS21820	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H7F35_RS21825	COG4154	Belongs to the RbsD FucU family
H7F35_RS21830	COG1012	belongs to the aldehyde dehydrogenase family
H7F35_RS21835	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
H7F35_RS21840	COG1349	DNA-binding transcription factor activity
H7F35_RS21845	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
H7F35_RS21855	COG1028	Short-chain dehydrogenase reductase Sdr
H7F35_RS21890	COG0583	DNA-binding transcription factor activity
H7F35_RS21895	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H7F35_RS21935	COG0222	ribosome binding
H7F35_RS21950	COG4797	methyltransferase
H7F35_RS21950	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
H7F35_RS21985	COG1058	Belongs to the CinA family
H7F35_RS21985	COG1546	Belongs to the CinA family
H7F35_RS21990	COG0174	glutamine synthetase
H7F35_RS22000	COG3852	Histidine kinase
H7F35_RS22005	COG2204	response regulator
H7F35_RS22015	COG0708	Exodeoxyribonuclease III
H7F35_RS22045	COG3723	Recombinational DNA repair protein, rece pathway
H7F35_RS22135	COG1598	PFAM Uncharacterised protein family UPF0150
H7F35_RS22140	COG1724	mRNA binding
H7F35_RS22165	COG2366	antibiotic biosynthetic process
H7F35_RS22210	COG2070	2-Nitropropane dioxygenase
H7F35_RS22215	COG0318	PFAM AMP-dependent synthetase and ligase
H7F35_RS22220	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H7F35_RS22240	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
H7F35_RS22260	COG0277	FAD linked oxidase domain protein
H7F35_RS22270	COG1295	ribonuclease BN
H7F35_RS22280	COG3118	belongs to the thioredoxin family
H7F35_RS22290	COG3181	Tripartite tricarboxylate transporter family receptor
H7F35_RS22295	COG2267	carboxylic ester hydrolase activity
H7F35_RS22315	COG2814	Major facilitator Superfamily
H7F35_RS22335	COG1957	nucleoside hydrolase
H7F35_RS22340	COG3181	Tripartite tricarboxylate transporter family receptor
H7F35_RS22345	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
H7F35_RS22350	COG0583	DNA-binding transcription factor activity
H7F35_RS22415	COG1126	abc transporter atp-binding protein
H7F35_RS22420	COG0765	amino acid transport
H7F35_RS22430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7F35_RS22440	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H7F35_RS22450	COG1538	Outer membrane efflux protein
H7F35_RS22465	COG3265	gluconokinase activity
H7F35_RS22475	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
H7F35_RS22485	COG0431	NADPH-dependent FMN reductase
H7F35_RS22495	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
H7F35_RS22520	COG0346	lactoylglutathione lyase activity
H7F35_RS22530	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
H7F35_RS22535	COG0596	Alpha beta hydrolase
H7F35_RS22545	COG0625	glutathione transferase activity
H7F35_RS22560	COG0583	DNA-binding transcription factor activity
H7F35_RS22565	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
H7F35_RS22570	COG2719	SpoVR family
H7F35_RS22575	COG2718	Belongs to the UPF0229 family
H7F35_RS22580	COG2766	serine protein kinase
H7F35_RS22585	COG0484	heat shock protein binding
H7F35_RS22590	COG0443	Heat shock 70 kDa protein
H7F35_RS22595	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
H7F35_RS22610	COG0688	phosphatidylethanolamine metabolic process
H7F35_RS22620	COG2706	6-phosphogluconolactonase activity
H7F35_RS22635	COG2721	sulfolactate sulfo-lyase activity
H7F35_RS22650	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
H7F35_RS22660	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H7F35_RS22665	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7F35_RS22670	COG1126	abc transporter atp-binding protein
H7F35_RS22675	COG0765	amino acid transport
H7F35_RS22680	COG0765	amino acid transport
H7F35_RS22685	COG2186	Transcriptional regulator
H7F35_RS22690	COG3181	Tripartite tricarboxylate transporter family receptor
H7F35_RS22695	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H7F35_RS22705	COG3181	Tripartite tricarboxylate transporter family receptor
H7F35_RS22715	COG1012	belongs to the aldehyde dehydrogenase family
H7F35_RS22735	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H7F35_RS22745	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
H7F35_RS22755	COG1802	Transcriptional regulator
H7F35_RS22800	COG0583	DNA-binding transcription factor activity
H7F35_RS22810	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H7F35_RS22830	COG2814	Major facilitator Superfamily
H7F35_RS22840	COG0358	DNA primase activity
H7F35_RS22845	COG1295	ribonuclease BN
H7F35_RS22845	COG1959	2 iron, 2 sulfur cluster binding
H7F35_RS22860	COG0123	including yeast histone deacetylase and acetoin utilization protein
H7F35_RS22865	COG0824	Thioesterase
H7F35_RS22875	COG3237	CsbD-like
H7F35_RS22880	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
H7F35_RS22890	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H7F35_RS22905	COG0477	Major facilitator Superfamily
H7F35_RS22915	COG1309	transcriptional regulator
H7F35_RS22920	COG1611	Belongs to the LOG family
H7F35_RS22925	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
H7F35_RS22940	COG0596	Alpha beta hydrolase
H7F35_RS22945	COG0405	Gamma-glutamyltransferase
H7F35_RS22950	COG0322	excinuclease ABC activity
H7F35_RS22960	COG0697	spore germination
H7F35_RS22965	COG0583	DNA-binding transcription factor activity
H7F35_RS22970	COG0596	Alpha beta hydrolase
H7F35_RS22975	COG0473	3-isopropylmalate dehydrogenase activity
H7F35_RS22990	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H7F35_RS23290	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
H7F35_RS23295	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
H7F35_RS23310	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
H7F35_RS23320	COG3193	protein, possibly involved in utilization of glycolate and propanediol
H7F35_RS23350	COG3128	pkhd-type hydroxylase
H7F35_RS23355	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
H7F35_RS23390	COG3634	alkyl hydroperoxide reductase activity
H7F35_RS23395	COG4771	TonB-dependent receptor
H7F35_RS23400	COG3720	iron ion transport
H7F35_RS23410	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7F35_RS23415	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
H7F35_RS23420	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
H7F35_RS23435	COG0360	Binds together with S18 to 16S ribosomal RNA
H7F35_RS23440	COG2965	DNA replication, synthesis of RNA primer
H7F35_RS23445	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
H7F35_RS23450	COG0359	binds to the 23S rRNA
H7F35_RS23485	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
H7F35_RS23490	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H7F35_RS23500	COG0436	Aminotransferase
H7F35_RS23515	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
H7F35_RS23520	COG1763	Mo-molybdopterin cofactor biosynthetic process
H7F35_RS23525	COG0303	'Molybdopterin
H7F35_RS23535	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H7F35_RS23545	COG0791	NLP P60 protein
H7F35_RS23545	COG1388	LysM domain
H7F35_RS23560	COG0314	molybdopterin synthase activity
H7F35_RS23565	COG3181	Tripartite tricarboxylate transporter family receptor
H7F35_RS23570	COG0542	response to heat
H7F35_RS23580	COG1022	Amp-dependent synthetase and ligase
H7F35_RS23610	COG1309	transcriptional regulator
H7F35_RS23615	COG1024	Enoyl-CoA hydratase
H7F35_RS23620	COG0183	Belongs to the thiolase family
H7F35_RS23635	COG0583	DNA-binding transcription factor activity
H7F35_RS23665	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H7F35_RS23680	COG2814	Major facilitator Superfamily
H7F35_RS23700	COG3181	Tripartite tricarboxylate transporter family receptor
H7F35_RS23705	COG4974	Belongs to the 'phage' integrase family
H7F35_RS23715	COG3181	Tripartite tricarboxylate transporter family receptor
H7F35_RS23740	COG2833	Protein of unknown function (DUF455)
H7F35_RS23750	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
H7F35_RS23765	COG3201	nicotinamide mononucleotide transporter
H7F35_RS23770	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
H7F35_RS23775	COG0148	phosphopyruvate hydratase activity
H7F35_RS23785	COG2877	3-deoxy-8-phosphooctulonate synthase activity
H7F35_RS23790	COG0504	CTP synthase activity
H7F35_RS23795	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H7F35_RS23805	COG0756	dUTP diphosphatase activity
H7F35_RS23815	COG1047	Peptidyl-prolyl cis-trans
H7F35_RS23820	COG2850	peptidyl-arginine hydroxylation
H7F35_RS23835	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
H7F35_RS23840	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
H7F35_RS23845	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H7F35_RS23865	COG2814	Major facilitator Superfamily
H7F35_RS23875	COG0583	DNA-binding transcription factor activity
H7F35_RS23900	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H7F35_RS23905	COG0741	lytic transglycosylase activity
H7F35_RS23905	COG0739	heme binding
H7F35_RS23905	COG1196	nuclear chromosome segregation
H7F35_RS23940	COG0765	amino acid transport
H7F35_RS23945	COG0765	amino acid transport
H7F35_RS23950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7F35_RS23955	COG1126	abc transporter atp-binding protein
H7F35_RS23965	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H7F35_RS23975	COG1609	Transcriptional regulator
H7F35_RS23990	COG2197	response regulator
H7F35_RS24015	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H7F35_RS24030	COG1024	Enoyl-CoA hydratase
H7F35_RS24040	COG0583	DNA-binding transcription factor activity
H7F35_RS24055	COG2271	Major facilitator Superfamily
H7F35_RS24090	COG1305	Transglutaminase-like
H7F35_RS24115	COG1024	Enoyl-CoA hydratase
H7F35_RS24120	COG2308	Evidence 4 Homologs of previously reported genes of
H7F35_RS24135	COG2194	sulfuric ester hydrolase activity
H7F35_RS24140	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
H7F35_RS24155	COG3842	ATPase activity
H7F35_RS24160	COG3842	ATPase activity
H7F35_RS24170	COG0395	ABC-type sugar transport system, permease component
H7F35_RS24200	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H7F35_RS24215	COG1131	(ABC) transporter
H7F35_RS24245	COG2951	lytic endotransglycosylase activity
H7F35_RS24260	COG0714	Associated with various cellular activities
H7F35_RS24270	COG1511	domain protein
H7F35_RS24270	COG3264	Mechanosensitive ion channel
H7F35_RS24285	COG1960	acyl-CoA dehydrogenase activity
H7F35_RS24300	COG4988	ABC transporter
H7F35_RS24305	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
H7F35_RS24310	COG1271	oxidase subunit
H7F35_RS24315	COG1294	oxidase, subunit
H7F35_RS24335	COG0318	PFAM AMP-dependent synthetase and ligase
H7F35_RS24345	COG2030	dehydratase
H7F35_RS24355	COG1028	Short-chain dehydrogenase reductase Sdr
H7F35_RS24360	COG1024	Enoyl-CoA hydratase
H7F35_RS24370	COG3128	pkhd-type hydroxylase
H7F35_RS24375	COG4774	siderophore transport
H7F35_RS24385	COG0640	Transcriptional regulator
H7F35_RS24400	COG3795	YCII-related domain
H7F35_RS24405	COG3795	YCII-related domain
H7F35_RS24410	COG0477	Major facilitator Superfamily
H7F35_RS24420	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
H7F35_RS24435	COG2985	domain, Protein
H7F35_RS24440	COG2985	domain, Protein
H7F35_RS24475	COG0642	Histidine kinase
H7F35_RS24480	COG0745	RESPONSE REGULATOR receiver
H7F35_RS24495	COG1414	Transcriptional regulator
H7F35_RS24500	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
H7F35_RS24505	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
H7F35_RS24515	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H7F35_RS24520	COG2814	Major facilitator Superfamily
H7F35_RS24525	COG0596	Alpha beta hydrolase
H7F35_RS24530	COG3185	4-Hydroxyphenylpyruvate dioxygenase
H7F35_RS24530	COG1082	Xylose isomerase domain protein TIM barrel
H7F35_RS24535	COG0477	Major facilitator Superfamily
H7F35_RS24605	COG0583	DNA-binding transcription factor activity
H7F35_RS24615	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
H7F35_RS24620	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
H7F35_RS24630	COG2070	2-Nitropropane dioxygenase
H7F35_RS24655	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
H7F35_RS24655	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
H7F35_RS24660	COG0509	glycine decarboxylation via glycine cleavage system
H7F35_RS24665	COG0404	The glycine cleavage system catalyzes the degradation of glycine
H7F35_RS24690	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
H7F35_RS24690	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
H7F35_RS24700	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
H7F35_RS24705	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H7F35_RS24730	COG1028	Short-chain dehydrogenase reductase Sdr
H7F35_RS24740	COG0824	Thioesterase
H7F35_RS24750	COG0642	Histidine kinase
H7F35_RS24755	COG0745	RESPONSE REGULATOR receiver
H7F35_RS24765	COG0671	phosphoesterase, PA-phosphatase related
H7F35_RS24770	COG2194	sulfuric ester hydrolase activity
H7F35_RS24800	COG4302	ethanolamine ammonia-lyase activity
H7F35_RS24805	COG4303	Ethanolamine ammonia lyase large subunit
H7F35_RS24810	COG0531	amino acid
H7F35_RS24815	COG0545	Peptidyl-prolyl cis-trans isomerase
H7F35_RS24840	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
H7F35_RS24855	COG3284	Transcriptional regulator
H7F35_RS24860	COG1012	belongs to the aldehyde dehydrogenase family
H7F35_RS24875	COG3585	molybdate ion transport
H7F35_RS24970	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H7F35_RS24975	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H7F35_RS25015	COG0456	acetyltransferase
H7F35_RS25035	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H7F35_RS25045	COG0436	Aminotransferase
H7F35_RS25065	COG1960	acyl-CoA dehydrogenase activity
H7F35_RS25070	COG1024	Enoyl-CoA hydratase
H7F35_RS25080	COG2223	nitrite transmembrane transporter activity
H7F35_RS25090	COG0583	DNA-binding transcription factor activity
H7F35_RS25105	COG0583	DNA-binding transcription factor activity
H7F35_RS25110	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
H7F35_RS25125	COG3181	Tripartite tricarboxylate transporter family receptor
H7F35_RS25135	COG2818	Glycosylase
H7F35_RS25140	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H7F35_RS25170	COG0625	glutathione transferase activity
H7F35_RS25175	COG1183	phosphatidylcholine synthase activity
H7F35_RS25180	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H7F35_RS25180	COG0519	Catalyzes the synthesis of GMP from XMP
H7F35_RS25185	COG1349	DNA-binding transcription factor activity
H7F35_RS25215	COG1272	protein, Hemolysin III
H7F35_RS25235	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
H7F35_RS25250	COG0673	inositol 2-dehydrogenase activity
H7F35_RS25260	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
H7F35_RS25265	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H7F35_RS25270	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H7F35_RS25280	COG1309	transcriptional regulator
H7F35_RS25285	COG0028	Belongs to the TPP enzyme family
H7F35_RS25315	COG2224	Isocitrate lyase
H7F35_RS25320	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
H7F35_RS25325	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
H7F35_RS25330	COG0291	Belongs to the bacterial ribosomal protein bL35 family
H7F35_RS25335	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
H7F35_RS25340	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
H7F35_RS25345	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H7F35_RS25345	COG0072	phenylalanine-tRNA ligase activity
H7F35_RS25350	COG0776	regulation of translation
H7F35_RS25375	COG1401	restriction endodeoxyribonuclease activity
H7F35_RS25445	COG0583	DNA-binding transcription factor activity
H7F35_RS25455	COG1396	sequence-specific DNA binding
H7F35_RS25460	COG3181	Tripartite tricarboxylate transporter family receptor
H7F35_RS25480	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H7F35_RS25515	COG0477	Major facilitator Superfamily
H7F35_RS25545	COG1764	response to oxidative stress
H7F35_RS25550	COG4106	trans-aconitate 2-methyltransferase activity
H7F35_RS25555	COG0583	DNA-binding transcription factor activity
H7F35_RS25570	COG3042	response to heat
H7F35_RS25585	COG0811	peptide transport
H7F35_RS25625	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
H7F35_RS25645	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H7F35_RS25665	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H7F35_RS25685	COG1132	(ABC) transporter
H7F35_RS25720	COG2267	carboxylic ester hydrolase activity
H7F35_RS25755	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H7F35_RS25795	COG3148	PFAM DTW domain containing protein
H7F35_RS25840	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H7F35_RS25860	COG3045	CreA protein
H7F35_RS25895	COG3243	poly(R)-hydroxyalkanoic acid synthase
H7F35_RS25900	COG0183	Belongs to the thiolase family
H7F35_RS25915	COG0625	glutathione transferase activity
H7F35_RS25925	COG0583	DNA-binding transcription factor activity
H7F35_RS25935	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
H7F35_RS25965	COG1360	Flagellar Motor Protein
H7F35_RS25975	COG1058	Belongs to the CinA family
H7F35_RS25975	COG1546	Belongs to the CinA family
H7F35_RS25985	COG1028	Short-chain dehydrogenase reductase Sdr
H7F35_RS25990	COG1301	dicarboxylic acid transport
H7F35_RS25995	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H7F35_RS25995	COG4651	solute:proton antiporter activity
H7F35_RS26010	COG4774	siderophore transport
H7F35_RS26070	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H7F35_RS26085	COG0583	DNA-binding transcription factor activity
H7F35_RS26090	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
H7F35_RS26115	COG1793	dna ligase
H7F35_RS26150	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
H7F35_RS26195	COG2197	response regulator
H7F35_RS26200	COG4585	Histidine kinase
H7F35_RS26230	COG0402	S-adenosylhomocysteine deaminase activity
H7F35_RS26235	COG4603	Belongs to the binding-protein-dependent transport system permease family
H7F35_RS26245	COG3845	ABC transporter
H7F35_RS26265	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
H7F35_RS26270	COG1309	transcriptional regulator
H7F35_RS26290	COG3181	Tripartite tricarboxylate transporter family receptor
H7F35_RS26305	COG0583	DNA-binding transcription factor activity
H7F35_RS26340	COG2249	NAD(P)H dehydrogenase (quinone) activity
H7F35_RS26345	COG0583	DNA-binding transcription factor activity
H7F35_RS26375	COG0116	Belongs to the methyltransferase superfamily
H7F35_RS26405	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H7F35_RS26425	COG0028	Belongs to the TPP enzyme family
H7F35_RS26435	COG0745	RESPONSE REGULATOR receiver
H7F35_RS26465	COG2814	Major facilitator Superfamily
H7F35_RS26470	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H7F35_RS26480	COG1802	Transcriptional regulator
H7F35_RS26485	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
H7F35_RS26485	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
H7F35_RS26495	COG1703	isobutyryl-CoA mutase activity
H7F35_RS26505	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H7F35_RS26510	COG4770	biotin carboxylase activity
H7F35_RS26515	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
H7F35_RS26525	COG1522	sequence-specific DNA binding
H7F35_RS26530	COG0697	spore germination
H7F35_RS26540	COG2878	Part of a membrane complex involved in electron transport
H7F35_RS26555	COG0556	nucleotide-excision repair
H7F35_RS26560	COG1959	2 iron, 2 sulfur cluster binding
H7F35_RS26565	COG1104	cysteine desulfurase activity
H7F35_RS26570	COG0822	iron-sulfur transferase activity
H7F35_RS26580	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
H7F35_RS26585	COG0443	Heat shock 70 kDa protein
H7F35_RS26590	COG0633	Ferredoxin
H7F35_RS26610	COG0579	oxidoreductase
H7F35_RS26625	COG0167	dihydroorotate dehydrogenase activity
H7F35_RS26630	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
H7F35_RS26645	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
H7F35_RS26650	COG4566	intracellular signal transduction
H7F35_RS26660	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
H7F35_RS26665	COG0508	dehydrogenase complex catalyzes the overall conversion of
H7F35_RS26670	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
H7F35_RS26675	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H7F35_RS26680	COG0791	NLP P60 protein
H7F35_RS26715	COG0567	Dehydrogenase, E1 component
H7F35_RS26720	COG0508	dehydrogenase complex catalyzes the overall conversion of
H7F35_RS26730	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H7F35_RS26735	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
H7F35_RS26755	COG1199	ATP-dependent helicase activity
H7F35_RS26765	COG0564	pseudouridine synthase activity
H7F35_RS26770	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
H7F35_RS26775	COG1187	pseudouridine synthase activity
H7F35_RS26780	COG0105	UTP biosynthetic process
H7F35_RS26785	COG0820	rRNA (adenine-C2-)-methyltransferase activity
H7F35_RS26800	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
H7F35_RS26805	COG0124	histidyl-tRNA synthetase
H7F35_RS26815	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H7F35_RS26820	COG1160	GTP binding
H7F35_RS26825	COG1923	regulation of RNA biosynthetic process
H7F35_RS26830	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H7F35_RS26835	COG0330	HflC and HflK could
H7F35_RS26840	COG0330	HflC and HflK could
H7F35_RS26850	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
H7F35_RS26855	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
H7F35_RS26885	COG0626	cystathionine gamma-synthase activity
H7F35_RS26900	COG4181	ATPase activity
H7F35_RS26915	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H7F35_RS26935	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H7F35_RS26945	COG0667	Aldo Keto reductase
H7F35_RS26950	COG2059	Chromate
H7F35_RS26960	COG1295	ribonuclease BN
H7F35_RS26985	COG1028	Short-chain dehydrogenase reductase Sdr
H7F35_RS26990	COG0456	acetyltransferase
H7F35_RS26990	COG1846	Transcriptional regulator
H7F35_RS27010	COG1942	4-Oxalocrotonate Tautomerase
H7F35_RS27025	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H7F35_RS27030	COG1028	Short-chain dehydrogenase reductase Sdr
H7F35_RS27035	COG1522	sequence-specific DNA binding
H7F35_RS27055	COG1024	Enoyl-CoA hydratase
H7F35_RS27080	COG0583	DNA-binding transcription factor activity
H7F35_RS27100	COG0179	Fumarylacetoacetate (FAA) hydrolase
H7F35_RS27210	COG4695	Portal protein
H7F35_RS27245	COG0625	glutathione transferase activity
H7F35_RS27255	COG0492	ferredoxin-NADP+ reductase activity
H7F35_RS27275	COG0248	Ppx GppA phosphatase
H7F35_RS27280	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
H7F35_RS27285	COG0573	inorganic phosphate transmembrane transporter activity
H7F35_RS27290	COG0581	inorganic phosphate transmembrane transporter activity
H7F35_RS27295	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H7F35_RS27310	COG5002	protein histidine kinase activity
H7F35_RS27315	COG0534	Mate efflux family protein
H7F35_RS27325	COG0254	rRNA binding
H7F35_RS27330	COG0673	inositol 2-dehydrogenase activity
H7F35_RS27335	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
H7F35_RS27350	COG1074	ATP-dependent DNA helicase activity
H7F35_RS27415	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
H7F35_RS27420	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
H7F35_RS27425	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
H7F35_RS27435	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H7F35_RS27445	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H7F35_RS27455	COG0741	lytic transglycosylase activity
H7F35_RS27455	COG1388	LysM domain
H7F35_RS27460	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H7F35_RS27470	COG0328	RNA-DNA hybrid ribonuclease activity
H7F35_RS27480	COG0746	molybdenum cofactor guanylyltransferase activity
H7F35_RS27485	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
H7F35_RS27510	COG1012	belongs to the aldehyde dehydrogenase family
H7F35_RS27520	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H7F35_RS27580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H7F35_RS27610	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
H7F35_RS27635	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
H7F35_RS27660	COG0028	Belongs to the TPP enzyme family
H7F35_RS27665	COG0440	acetolactate synthase activity
H7F35_RS27675	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
H7F35_RS27680	COG1183	phosphatidylcholine synthase activity
H7F35_RS27685	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H7F35_RS27690	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H7F35_RS27700	COG1414	Transcriptional regulator
H7F35_RS27705	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
H7F35_RS27710	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
H7F35_RS27740	COG1414	Transcriptional regulator
H7F35_RS27755	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H7F35_RS27790	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H7F35_RS27795	COG1742	UPF0060 membrane protein
H7F35_RS27820	COG2022	thiamine diphosphate biosynthetic process
H7F35_RS27835	COG0351	phosphomethylpyrimidine kinase
H7F35_RS27845	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
H7F35_RS27860	COG0492	ferredoxin-NADP+ reductase activity
H7F35_RS27865	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
H7F35_RS27870	COG2895	sulfate adenylyltransferase (ATP) activity
H7F35_RS27870	COG0529	Catalyzes the synthesis of activated sulfate
H7F35_RS27875	COG0175	sulfate reduction
H7F35_RS27895	COG0840	transmembrane signaling receptor activity
H7F35_RS27910	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H7F35_RS27925	COG4172	Belongs to the ABC transporter superfamily
H7F35_RS27930	COG1446	asparaginase
H7F35_RS27940	COG2755	lipolytic protein G-D-S-L family
H7F35_RS27940	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
H7F35_RS27955	COG0667	Aldo Keto reductase
H7F35_RS27960	COG3360	Dodecin
H7F35_RS27975	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H7F35_RS27980	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H7F35_RS27985	COG1473	amidohydrolase
H7F35_RS27995	COG1126	abc transporter atp-binding protein
H7F35_RS28000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7F35_RS28010	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H7F35_RS28025	COG0601	transmembrane transport
H7F35_RS28065	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H7F35_RS28070	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H7F35_RS28085	COG1228	amidohydrolase
H7F35_RS28090	COG1042	CoA-binding domain protein
H7F35_RS28090	COG0045	succinate-CoA ligase (ADP-forming) activity
H7F35_RS28090	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H7F35_RS28140	COG1459	type II secretion system
H7F35_RS28205	COG4795	General secretion pathway protein
H7F35_RS28210	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H7F35_RS28245	COG0583	DNA-binding transcription factor activity
H7F35_RS28250	COG1028	Short-chain dehydrogenase reductase Sdr
H7F35_RS28255	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H7F35_RS28275	COG0583	DNA-binding transcription factor activity
H7F35_RS28300	COG2197	response regulator
H7F35_RS28305	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H7F35_RS28310	COG0297	glycogen (starch) synthase activity
H7F35_RS28345	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H7F35_RS28355	COG0489	protein tyrosine kinase activity
H7F35_RS28355	COG3206	protein involved in exopolysaccharide biosynthesis
H7F35_RS28400	COG1388	LysM domain
H7F35_RS28400	COG4942	peptidase
H7F35_RS28415	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H7F35_RS28430	COG2207	Transcriptional regulator
H7F35_RS28465	COG1028	Short-chain dehydrogenase reductase Sdr
H7F35_RS28485	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H7F35_RS28490	COG0420	3'-5' exonuclease activity
H7F35_RS28500	COG0768	penicillin binding
H7F35_RS28575	COG1028	Short-chain dehydrogenase reductase Sdr
H7F35_RS28585	COG1028	Short-chain dehydrogenase reductase Sdr
H7F35_RS28590	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H7F35_RS28595	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H7F35_RS28610	COG0583	DNA-binding transcription factor activity
H7F35_RS28615	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H7F35_RS28645	COG0583	DNA-binding transcription factor activity
H7F35_RS28650	COG1960	acyl-CoA dehydrogenase activity
H7F35_RS28660	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H7F35_RS28665	COG2909	trisaccharide binding
H7F35_RS28670	COG1028	Short-chain dehydrogenase reductase Sdr
H7F35_RS28675	COG0318	PFAM AMP-dependent synthetase and ligase
H7F35_RS28690	COG3181	Tripartite tricarboxylate transporter family receptor
H7F35_RS28700	COG1960	acyl-CoA dehydrogenase activity
H7F35_RS28720	COG1028	Short-chain dehydrogenase reductase Sdr
H7F35_RS28725	COG0318	PFAM AMP-dependent synthetase and ligase
H7F35_RS28730	COG3181	Tripartite tricarboxylate transporter family receptor
H7F35_RS28745	COG1960	acyl-CoA dehydrogenase activity
H7F35_RS28750	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H7F35_RS28815	COG2885	chlorophyll binding
H7F35_RS28950	COG1522	sequence-specific DNA binding
H7F35_RS28960	COG2259	Doxx family
H7F35_RS29000	COG1028	Short-chain dehydrogenase reductase Sdr
H7F35_RS29010	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
H7F35_RS29015	COG3181	Tripartite tricarboxylate transporter family receptor
H7F35_RS29060	COG0640	Transcriptional regulator
H7F35_RS29075	COG0642	Histidine kinase
H7F35_RS29105	COG0671	phosphoesterase, PA-phosphatase related
H7F35_RS29120	COG0671	phosphoesterase, PA-phosphatase related
H7F35_RS29125	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
H7F35_RS29145	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
H7F35_RS29220	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
H7F35_RS29235	COG2197	response regulator
H7F35_RS29260	COG0789	Transcriptional regulator
H7F35_RS29270	COG2010	Cytochrome c
H7F35_RS29270	COG1529	Aldehyde oxidase and xanthine dehydrogenase
H7F35_RS29290	COG0583	DNA-binding transcription factor activity
H7F35_RS29305	COG2267	carboxylic ester hydrolase activity
H7F35_RS29315	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H7F35_RS29385	COG0642	Histidine kinase
H7F35_RS29390	COG0586	Pfam SNARE associated Golgi protein
H7F35_RS29395	COG4644	lycopene metabolic process
H7F35_RS29445	COG2205	protein histidine kinase activity
H7F35_RS29545	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H7F35_RS29565	COG1063	alcohol dehydrogenase
H7F35_RS29590	COG0784	Response regulator, receiver
H7F35_RS29590	COG4191	Histidine kinase
H7F35_RS29600	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
H7F35_RS29615	COG4716	Myosin-crossreactive antigen
H7F35_RS29635	COG0666	response to abiotic stimulus
H7F35_RS29640	COG0084	hydrolase, TatD family'
H7F35_RS29655	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
H7F35_RS29660	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H7F35_RS29710	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H7F35_RS29725	COG0745	RESPONSE REGULATOR receiver
H7F35_RS29740	COG1538	Outer membrane efflux protein
H7F35_RS29765	COG2183	response to ionizing radiation
H7F35_RS29770	COG4585	Histidine kinase
H7F35_RS29775	COG2201	protein-glutamate methylesterase activity
H7F35_RS29815	COG0534	Mate efflux family protein
H7F35_RS29830	COG4774	siderophore transport
H7F35_RS29835	COG3712	iron ion homeostasis
H7F35_RS29840	COG1595	DNA-templated transcription, initiation
H7F35_RS29850	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H7F35_RS29855	COG1609	Transcriptional regulator
H7F35_RS29860	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
H7F35_RS29860	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
H7F35_RS29865	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
H7F35_RS29880	COG0477	Major facilitator Superfamily
H7F35_RS29890	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
H7F35_RS29890	COG3008	intermembrane lipid transfer
H7F35_RS29895	COG2995	paraquat-inducible protein a
H7F35_RS29900	COG2995	paraquat-inducible protein a
H7F35_RS29905	COG2814	Major facilitator Superfamily
H7F35_RS29910	COG2814	Major facilitator Superfamily
H7F35_RS29915	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H7F35_RS29925	COG1028	Short-chain dehydrogenase reductase Sdr
H7F35_RS29965	COG3181	Tripartite tricarboxylate transporter family receptor
H7F35_RS29970	COG0583	DNA-binding transcription factor activity
H7F35_RS29980	COG4792	protein secretion
H7F35_RS29985	COG1684	flagellar biosynthetic protein fliR
H7F35_RS30030	COG1450	Type ii and iii secretion system protein
H7F35_RS30040	COG4789	Type iii secretion
H7F35_RS30070	COG0583	DNA-binding transcription factor activity
H7F35_RS30090	COG0583	DNA-binding transcription factor activity
H7F35_RS30095	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
H7F35_RS30100	COG0511	ligase activity, forming carbon-carbon bonds
H7F35_RS30105	COG0439	Biotin carboxylase
H7F35_RS30115	COG1984	allophanate hydrolase subunit 2
H7F35_RS30120	COG1879	ABC-type sugar transport system periplasmic component
H7F35_RS30125	COG1129	ABC transporter
H7F35_RS30130	COG1172	Belongs to the binding-protein-dependent transport system permease family
H7F35_RS30135	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H7F35_RS30145	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H7F35_RS30155	COG0247	lactate metabolic process
H7F35_RS30155	COG0277	FAD linked oxidase domain protein
H7F35_RS30160	COG1802	Transcriptional regulator
H7F35_RS30180	COG0583	DNA-binding transcription factor activity
H7F35_RS30185	COG2814	Major facilitator Superfamily
H7F35_RS30230	COG1971	Probably functions as a manganese efflux pump
H7F35_RS30245	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H7F35_RS30255	COG0583	DNA-binding transcription factor activity
H7F35_RS30260	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
H7F35_RS30280	COG1960	acyl-CoA dehydrogenase activity
H7F35_RS30285	COG2130	NADP-dependent
H7F35_RS30310	COG1960	acyl-CoA dehydrogenase activity
H7F35_RS30320	COG0183	Belongs to the thiolase family
H7F35_RS30325	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H7F35_RS30330	COG1250	3-hydroxyacyl-CoA dehydrogenase
H7F35_RS30330	COG1024	Enoyl-CoA hydratase
H7F35_RS30340	COG0411	ABC transporter
H7F35_RS30350	COG0559	Belongs to the binding-protein-dependent transport system permease family
H7F35_RS30365	COG0318	PFAM AMP-dependent synthetase and ligase
H7F35_RS30380	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
H7F35_RS30385	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
H7F35_RS30390	COG2917	probably involved in intracellular septation
H7F35_RS30400	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H7F35_RS30410	COG0047	phosphoribosylformylglycinamidine synthase activity
H7F35_RS30410	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H7F35_RS30415	COG0024	Methionine aminopeptidase
H7F35_RS30420	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
H7F35_RS30425	COG2203	Gaf domain
H7F35_RS30425	COG2199	diguanylate cyclase activity
H7F35_RS30430	COG3447	MASE1 domain protein
H7F35_RS30430	COG5002	protein histidine kinase activity
H7F35_RS30430	COG5001	Diguanylate cyclase
H7F35_RS30435	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H7F35_RS30460	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
H7F35_RS30465	COG0667	Aldo Keto reductase
H7F35_RS30475	COG1396	sequence-specific DNA binding
H7F35_RS30485	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H7F35_RS30495	COG0765	amino acid transport
H7F35_RS30500	COG4597	amino acid ABC transporter
H7F35_RS30505	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7F35_RS30510	COG2259	Doxx family
H7F35_RS30515	COG0242	peptide deformylase activity
H7F35_RS30525	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
H7F35_RS30535	COG1196	nuclear chromosome segregation
H7F35_RS30550	COG1538	Outer membrane efflux protein
H7F35_RS30560	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H7F35_RS30565	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
H7F35_RS30570	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
H7F35_RS30575	COG4208	sulfate ABC transporter
H7F35_RS30585	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
H7F35_RS30595	COG0450	alkyl hydroperoxide reductase
H7F35_RS30605	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
H7F35_RS30615	COG0765	amino acid transport
H7F35_RS30620	COG0765	amino acid transport
H7F35_RS30625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7F35_RS30630	COG2358	TRAP transporter, solute receptor (TAXI family
H7F35_RS30640	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
H7F35_RS30665	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H7F35_RS30670	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H7F35_RS30680	COG1045	serine acetyltransferase
H7F35_RS30695	COG1116	anion transmembrane transporter activity
H7F35_RS30700	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H7F35_RS30705	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H7F35_RS30710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H7F35_RS30725	COG0778	Nitroreductase
H7F35_RS30735	COG1116	anion transmembrane transporter activity
H7F35_RS30740	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H7F35_RS30745	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H7F35_RS30750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H7F35_RS30755	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H7F35_RS30765	COG0431	NADPH-dependent FMN reductase
H7F35_RS30775	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
H7F35_RS30780	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
H7F35_RS30780	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H7F35_RS30805	COG5002	protein histidine kinase activity
H7F35_RS30810	COG0745	RESPONSE REGULATOR receiver
H7F35_RS30815	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
H7F35_RS30820	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
H7F35_RS30835	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
H7F35_RS30860	COG1172	Belongs to the binding-protein-dependent transport system permease family
H7F35_RS30870	COG1129	ABC transporter
H7F35_RS30875	COG1879	ABC-type sugar transport system periplasmic component
H7F35_RS30880	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H7F35_RS30890	COG0427	acetyl-CoA hydrolase
H7F35_RS30895	COG3588	fructose-bisphosphate aldolase
H7F35_RS30910	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H7F35_RS30915	COG2423	ornithine cyclodeaminase activity
H7F35_RS30925	COG0583	DNA-binding transcription factor activity
H7F35_RS30930	COG0667	Aldo Keto reductase
H7F35_RS30960	COG2814	Major facilitator Superfamily
H7F35_RS30965	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
H7F35_RS30970	COG0154	amidase activity
H7F35_RS30980	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
H7F35_RS30985	COG2207	Transcriptional regulator
H7F35_RS30990	COG0667	Aldo Keto reductase
H7F35_RS30995	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
H7F35_RS31000	COG0156	8-amino-7-oxononanoate synthase activity
H7F35_RS31020	COG0583	DNA-binding transcription factor activity
H7F35_RS31065	COG1199	ATP-dependent helicase activity
H7F35_RS31065	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H7F35_RS31075	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
H7F35_RS31095	COG2186	Transcriptional regulator
H7F35_RS31110	COG1063	alcohol dehydrogenase
H7F35_RS31115	COG0765	amino acid transport
H7F35_RS31120	COG0765	amino acid transport
H7F35_RS31125	COG1126	abc transporter atp-binding protein
H7F35_RS31130	COG4948	Mandelate Racemase Muconate Lactonizing
H7F35_RS31135	COG0246	Mannitol dehydrogenase
H7F35_RS31145	COG0747	negative chemotaxis
H7F35_RS31150	COG0601	transmembrane transport
H7F35_RS31155	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H7F35_RS31165	COG0154	amidase activity
H7F35_RS31195	COG1619	proteins homologs of microcin C7 resistance protein MccF
H7F35_RS31225	COG4566	intracellular signal transduction
H7F35_RS31230	COG4191	Histidine kinase
H7F35_RS31300	COG0778	Nitroreductase
H7F35_RS31305	COG0519	Catalyzes the synthesis of GMP from XMP
H7F35_RS31305	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H7F35_RS31335	COG2867	negative regulation of translational initiation
H7F35_RS31340	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
H7F35_RS31375	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
H7F35_RS31380	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
H7F35_RS31385	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
H7F35_RS31390	COG0195	Participates in both transcription termination and antitermination
H7F35_RS31390	COG2251	uridine kinase activity
H7F35_RS31395	COG0779	Required for maturation of 30S ribosomal subunits
H7F35_RS31400	COG0477	Major facilitator Superfamily
H7F35_RS31405	COG4172	Belongs to the ABC transporter superfamily
H7F35_RS31410	COG4239	(ABC) transporter, permease
H7F35_RS31415	COG4174	ABC transporter (Permease)
H7F35_RS31420	COG4166	transmembrane transport
H7F35_RS31430	COG1793	dna ligase
H7F35_RS31455	COG4983	Phage plasmid primase, P4 family domain protein
H7F35_RS31475	COG2204	response regulator
H7F35_RS31495	COG0784	Response regulator, receiver
H7F35_RS31495	COG2198	Histidine kinase
H7F35_RS31495	COG2205	protein histidine kinase activity
H7F35_RS31500	COG0745	RESPONSE REGULATOR receiver
H7F35_RS31505	COG0784	Response regulator, receiver
H7F35_RS31505	COG2205	protein histidine kinase activity
H7F35_RS31515	COG3181	Tripartite tricarboxylate transporter family receptor
H7F35_RS31540	COG0300	oxidoreductase activity
H7F35_RS31575	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
H7F35_RS31595	COG2831	hemolysin activation secretion protein
H7F35_RS31610	COG3210	domain, Protein
H7F35_RS31640	COG2003	Belongs to the UPF0758 family
H7F35_RS31680	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
H7F35_RS31690	COG0795	lipopolysaccharide-transporting ATPase activity
H7F35_RS31700	COG0583	DNA-binding transcription factor activity
H7F35_RS31705	COG0436	Aminotransferase
H7F35_RS31720	COG1643	Atp-dependent helicase
H7F35_RS31725	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H7F35_RS31730	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
H7F35_RS31730	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
H7F35_RS31735	COG1280	lysine exporter protein (LysE YggA)
H7F35_RS31750	COG2171	N-acyltransferase activity
H7F35_RS31760	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H7F35_RS31765	COG2890	protein-(glutamine-N5) methyltransferase activity
H7F35_RS31770	COG0488	(ABC) transporter
H7F35_RS31795	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
H7F35_RS31805	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H7F35_RS31810	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H7F35_RS31830	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H7F35_RS31835	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H7F35_RS31845	COG3251	PFAM MbtH domain protein
H7F35_RS31865	COG3181	Tripartite tricarboxylate transporter family receptor
H7F35_RS31875	COG0583	DNA-binding transcription factor activity
H7F35_RS31880	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H7F35_RS31895	COG1802	Transcriptional regulator
H7F35_RS31905	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
H7F35_RS31910	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H7F35_RS31915	COG4172	Belongs to the ABC transporter superfamily
H7F35_RS31920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H7F35_RS31930	COG0747	negative chemotaxis
H7F35_RS31950	COG3209	COG3209 Rhs family protein
H7F35_RS31970	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
H7F35_RS31980	COG2885	chlorophyll binding
H7F35_RS31985	COG0823	Involved in the tonB-independent uptake of proteins
H7F35_RS31990	COG1132	(ABC) transporter
H7F35_RS31995	COG1530	ribonuclease E activity
H7F35_RS32000	COG0424	maF-like protein
H7F35_RS32010	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
H7F35_RS32015	COG0799	negative regulation of ribosome biogenesis
H7F35_RS32020	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
H7F35_RS32025	COG0408	coproporphyrinogen oxidase activity
H7F35_RS32030	COG0151	Belongs to the GarS family
H7F35_RS32035	COG0217	transcriptional regulatory protein
H7F35_RS32040	COG2226	methyltransferase
H7F35_RS32095	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
H7F35_RS32110	COG0433	COG0433 Predicted ATPase
H7F35_RS32120	COG1595	DNA-templated transcription, initiation
H7F35_RS32135	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
H7F35_RS32140	COG1744	ABC transporter substrate-binding protein PnrA-like
H7F35_RS32145	COG0726	polysaccharide deacetylase
H7F35_RS32160	COG3845	ABC transporter
H7F35_RS32165	COG4603	Belongs to the binding-protein-dependent transport system permease family
H7F35_RS32170	COG1079	Belongs to the binding-protein-dependent transport system permease family
H7F35_RS32185	COG0402	S-adenosylhomocysteine deaminase activity
H7F35_RS32205	COG2925	Exonuclease
H7F35_RS32210	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H7F35_RS32215	COG0542	response to heat
H7F35_RS32220	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
H7F35_RS32330	COG0582	viral genome integration into host DNA
H7F35_RS32355	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H7F35_RS32360	COG1570	exodeoxyribonuclease VII activity
H7F35_RS32365	COG0811	peptide transport
H7F35_RS32370	COG0848	biopolymer transport protein
H7F35_RS32375	COG1663	tetraacyldisaccharide 4'-kinase activity
H7F35_RS32380	COG2835	tetraacyldisaccharide 4'-kinase activity
H7F35_RS32385	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
H7F35_RS32390	COG0563	adenylate kinase activity
H7F35_RS32395	COG0252	asparaginase activity
H7F35_RS32400	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H7F35_RS32410	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H7F35_RS32415	COG2814	Major facilitator Superfamily
H7F35_RS32420	COG1250	3-hydroxyacyl-CoA dehydrogenase
H7F35_RS32425	COG1024	Enoyl-CoA hydratase
H7F35_RS32450	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H7F35_RS32460	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H7F35_RS32465	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
H7F35_RS32470	COG1534	Rna-binding protein
H7F35_RS32485	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H7F35_RS32495	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
H7F35_RS32500	COG0505	Belongs to the CarA family
H7F35_RS32505	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H7F35_RS32510	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
H7F35_RS32515	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H7F35_RS32520	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H7F35_RS32525	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
H7F35_RS32530	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H7F35_RS32540	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H7F35_RS32545	COG0750	zinc metalloprotease
H7F35_RS32550	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
H7F35_RS32555	COG0575	Belongs to the CDS family
H7F35_RS32560	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
H7F35_RS32565	COG0233	cytoplasmic translational termination
H7F35_RS32570	COG0528	UMP kinase activity
H7F35_RS32575	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
H7F35_RS32580	COG0052	Belongs to the universal ribosomal protein uS2 family
H7F35_RS32600	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
H7F35_RS32600	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
H7F35_RS32605	COG1028	Short-chain dehydrogenase reductase Sdr
H7F35_RS32610	COG0557	exoribonuclease II activity
H7F35_RS32625	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
H7F35_RS32630	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
H7F35_RS32665	COG3179	chitinase
H7F35_RS32715	COG1475	DNA binding
H7F35_RS32730	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
H7F35_RS32745	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H7F35_RS32770	COG1028	Short-chain dehydrogenase reductase Sdr
H7F35_RS32795	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
H7F35_RS32795	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
H7F35_RS32800	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
H7F35_RS32800	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
H7F35_RS32805	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H7F35_RS32810	COG0560	Phosphoserine phosphatase
H7F35_RS32830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H7F35_RS32835	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H7F35_RS32845	COG0840	transmembrane signaling receptor activity
H7F35_RS32860	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
H7F35_RS32865	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
H7F35_RS32870	COG1492	cobalamin metabolic process
H7F35_RS32890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H7F35_RS32895	COG0657	acetylesterase activity
H7F35_RS32905	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
H7F35_RS32920	COG1346	cytolysis
H7F35_RS32935	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
H7F35_RS32955	COG0778	Nitroreductase
H7F35_RS32960	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
H7F35_RS32965	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
H7F35_RS32970	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7F35_RS32985	COG1797	cobyrinic acid a,c-diamide synthase activity
H7F35_RS32990	COG4206	TonB-dependent receptor
H7F35_RS32995	COG0038	chloride channel
H7F35_RS33025	COG0730	response to heat
H7F35_RS33035	COG0318	PFAM AMP-dependent synthetase and ligase
H7F35_RS33055	COG1802	Transcriptional regulator
H7F35_RS33060	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
H7F35_RS33075	COG0583	DNA-binding transcription factor activity
H7F35_RS33085	COG0583	DNA-binding transcription factor activity
H7F35_RS33090	COG0129	dihydroxy-acid dehydratase activity
H7F35_RS33105	COG4654	Cytochrome c, class I
H7F35_RS33115	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H7F35_RS33125	COG0583	DNA-binding transcription factor activity
H7F35_RS33130	COG2910	NAD(P)H-binding
H7F35_RS33135	COG0114	fumarate hydratase activity
H7F35_RS33145	COG4176	ABC-type proline glycine betaine transport system permease component
H7F35_RS33150	COG2113	Glycine betaine
H7F35_RS33160	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
H7F35_RS33190	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
H7F35_RS33195	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
H7F35_RS33200	COG0740	serine-type endopeptidase activity
H7F35_RS33205	COG0544	peptidyl-prolyl cis-trans isomerase activity
H7F35_RS33225	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H7F35_RS33230	COG3158	transport of potassium into the cell
H7F35_RS33240	COG1562	ergosterol biosynthetic process
H7F35_RS33245	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
H7F35_RS33255	COG1280	lysine exporter protein (LysE YggA)
H7F35_RS33265	COG1011	Hydrolase
H7F35_RS33270	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
H7F35_RS33275	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H7F35_RS33365	COG1469	GTP cyclohydrolase I activity
H7F35_RS33375	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
H7F35_RS33380	COG0735	belongs to the Fur family
H7F35_RS33405	COG0642	Histidine kinase
H7F35_RS33415	COG2326	polyphosphate kinase activity
H7F35_RS33440	COG4654	Cytochrome c, class I
H7F35_RS33445	COG4774	siderophore transport
H7F35_RS33450	COG2197	response regulator
H7F35_RS33470	COG0527	aspartate kinase activity
H7F35_RS33475	COG0037	tRNA processing
H7F35_RS33480	COG0825	malonyl-CoA metabolic process
H7F35_RS33490	COG0215	cysteine-tRNA ligase activity
H7F35_RS33510	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H7F35_RS33535	COG0741	lytic transglycosylase activity
H7F35_RS33540	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
H7F35_RS33545	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
H7F35_RS33580	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H7F35_RS33580	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H7F35_RS33595	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
H7F35_RS33600	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
H7F35_RS33605	COG0436	Aminotransferase
H7F35_RS33610	COG0824	Thioesterase
H7F35_RS33620	COG0848	biopolymer transport protein
H7F35_RS33645	COG1054	Belongs to the UPF0176 family
H7F35_RS33680	COG1741	Belongs to the pirin family
H7F35_RS33705	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H7F35_RS33705	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
H7F35_RS33710	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H7F35_RS33715	COG0220	tRNA (guanine-N7-)-methyltransferase activity
H7F35_RS33730	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H7F35_RS33825	COG3842	ATPase activity
H7F35_RS33845	COG2205	protein histidine kinase activity
H7F35_RS33845	COG0784	Response regulator, receiver
H7F35_RS33845	COG2198	Histidine kinase
H7F35_RS33850	COG3437	response regulator, receiver
H7F35_RS33860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7F35_RS33870	COG0583	DNA-binding transcription factor activity
H7F35_RS33890	COG0596	Alpha beta hydrolase
H7F35_RS33900	COG0745	RESPONSE REGULATOR receiver
H7F35_RS33910	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
H7F35_RS33925	COG0308	aminopeptidase N
H7F35_RS33930	COG2271	Major facilitator Superfamily
H7F35_RS33970	COG1012	belongs to the aldehyde dehydrogenase family
H7F35_RS33975	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
H7F35_RS33980	COG0028	Belongs to the TPP enzyme family
H7F35_RS33985	COG1028	Short-chain dehydrogenase reductase Sdr
H7F35_RS33990	COG1414	Transcriptional regulator
H7F35_RS34010	COG3181	Tripartite tricarboxylate transporter family receptor
H7F35_RS34015	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H7F35_RS34020	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
H7F35_RS34025	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
H7F35_RS34070	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H7F35_RS34085	COG1012	belongs to the aldehyde dehydrogenase family
H7F35_RS34100	COG1840	ABC-type Fe3 transport system, periplasmic component
H7F35_RS34105	COG3842	ATPase activity
H7F35_RS34125	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
H7F35_RS34135	COG0277	FAD linked oxidase domain protein
H7F35_RS34165	COG0583	DNA-binding transcription factor activity
H7F35_RS34195	COG0587	DNA-directed DNA polymerase activity
H7F35_RS34220	COG0583	DNA-binding transcription factor activity
H7F35_RS34245	COG0129	dihydroxy-acid dehydratase activity
H7F35_RS34285	COG3038	cytochrome b561
H7F35_RS34295	COG3384	dioxygenase
H7F35_RS34305	COG1132	(ABC) transporter
H7F35_RS34315	COG1309	transcriptional regulator
H7F35_RS34340	COG1024	Enoyl-CoA hydratase
H7F35_RS34350	COG3214	Protein conserved in bacteria
H7F35_RS34355	COG4774	siderophore transport
H7F35_RS34360	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
H7F35_RS34375	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
H7F35_RS34380	COG0802	atpase or kinase
H7F35_RS34385	COG0860	N-Acetylmuramoyl-L-alanine amidase
H7F35_RS34395	COG0586	Pfam SNARE associated Golgi protein
H7F35_RS34415	COG2271	Major facilitator Superfamily
H7F35_RS34420	COG0129	dihydroxy-acid dehydratase activity
H7F35_RS34425	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
H7F35_RS34435	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
H7F35_RS34440	COG4181	ATPase activity
H7F35_RS34450	COG3795	YCII-related domain
H7F35_RS34455	COG4941	Belongs to the sigma-70 factor family
H7F35_RS34465	COG0577	efflux transmembrane transporter activity
H7F35_RS34550	COG1566	PFAM secretion protein HlyD family protein
H7F35_RS34560	COG1846	Transcriptional regulator
H7F35_RS34565	COG1132	(ABC) transporter
H7F35_RS34575	COG0494	nUDIX hydrolase