locus-tag	class	description
AX767_RS00010	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AX767_RS00015	COG0746	molybdenum cofactor guanylyltransferase activity
AX767_RS00025	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AX767_RS00025	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AX767_RS00035	COG0328	RNA-DNA hybrid ribonuclease activity
AX767_RS00040	COG2226	methyltransferase
AX767_RS00045	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AX767_RS00055	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AX767_RS00065	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AX767_RS00075	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AX767_RS00080	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AX767_RS00120	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AX767_RS00125	COG0673	inositol 2-dehydrogenase activity
AX767_RS00130	COG0254	rRNA binding
AX767_RS00160	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AX767_RS00165	COG0581	inorganic phosphate transmembrane transporter activity
AX767_RS00170	COG0573	inorganic phosphate transmembrane transporter activity
AX767_RS00175	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AX767_RS00205	COG1272	protein, Hemolysin III
AX767_RS00215	COG0625	glutathione transferase activity
AX767_RS00390	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
AX767_RS00460	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AX767_RS00465	COG3723	Recombinational DNA repair protein, rece pathway
AX767_RS00525	COG0318	PFAM AMP-dependent synthetase and ligase
AX767_RS00535	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
AX767_RS00535	COG0778	Nitroreductase
AX767_RS00540	COG1024	Enoyl-CoA hydratase
AX767_RS00550	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AX767_RS00555	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AX767_RS00575	COG1846	Transcriptional regulator
AX767_RS00595	COG1028	Short-chain dehydrogenase reductase Sdr
AX767_RS00600	COG4689	acetoacetate decarboxylase
AX767_RS00615	COG1295	ribonuclease BN
AX767_RS00625	COG2059	Chromate
AX767_RS00630	COG0667	Aldo Keto reductase
AX767_RS00650	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AX767_RS00665	COG4181	ATPase activity
AX767_RS00680	COG0626	cystathionine gamma-synthase activity
AX767_RS00700	COG0330	HflC and HflK could
AX767_RS00710	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AX767_RS00715	COG1923	regulation of RNA biosynthetic process
AX767_RS00720	COG1160	GTP binding
AX767_RS00725	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AX767_RS00735	COG0124	histidyl-tRNA synthetase
AX767_RS00740	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AX767_RS00755	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AX767_RS00760	COG0105	UTP biosynthetic process
AX767_RS00770	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AX767_RS00775	COG0564	pseudouridine synthase activity
AX767_RS00795	COG0631	protein serine/threonine phosphatase activity
AX767_RS00805	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AX767_RS00810	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AX767_RS00815	COG0508	dehydrogenase complex catalyzes the overall conversion of
AX767_RS00820	COG0567	Dehydrogenase, E1 component
AX767_RS00850	COG2133	pyrroloquinoline quinone binding
AX767_RS00855	COG0791	NLP P60 protein
AX767_RS00860	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AX767_RS00865	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AX767_RS00875	COG0508	dehydrogenase complex catalyzes the overall conversion of
AX767_RS00880	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AX767_RS00890	COG4566	intracellular signal transduction
AX767_RS00895	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AX767_RS00910	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AX767_RS00915	COG0167	dihydroorotate dehydrogenase activity
AX767_RS00930	COG0579	oxidoreductase
AX767_RS00955	COG0633	Ferredoxin
AX767_RS00960	COG0443	Heat shock 70 kDa protein
AX767_RS00965	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AX767_RS00975	COG0822	iron-sulfur transferase activity
AX767_RS00980	COG1104	cysteine desulfurase activity
AX767_RS00985	COG1959	2 iron, 2 sulfur cluster binding
AX767_RS00990	COG0556	nucleotide-excision repair
AX767_RS01010	COG2878	Part of a membrane complex involved in electron transport
AX767_RS01020	COG4770	biotin carboxylase activity
AX767_RS01025	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AX767_RS01030	COG1703	isobutyryl-CoA mutase activity
AX767_RS01040	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AX767_RS01040	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AX767_RS01045	COG1802	Transcriptional regulator
AX767_RS01050	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AX767_RS01075	COG1301	dicarboxylic acid transport
AX767_RS01080	COG1028	Short-chain dehydrogenase reductase Sdr
AX767_RS01085	COG3842	ATPase activity
AX767_RS01090	COG1653	transport
AX767_RS01100	COG0395	ABC-type sugar transport system, permease component
AX767_RS01115	COG0183	Belongs to the thiolase family
AX767_RS01120	COG3243	poly(R)-hydroxyalkanoic acid synthase
AX767_RS01150	COG3045	CreA protein
AX767_RS01180	COG0642	Histidine kinase
AX767_RS01205	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AX767_RS01215	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AX767_RS01215	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AX767_RS01240	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AX767_RS01245	COG0509	glycine decarboxylation via glycine cleavage system
AX767_RS01255	COG1028	Short-chain dehydrogenase reductase Sdr
AX767_RS01375	COG0740	serine-type endopeptidase activity
AX767_RS01380	COG4695	Portal protein
AX767_RS01385	COG1802	Transcriptional regulator
AX767_RS01385	COG4626	Terminase
AX767_RS01570	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AX767_RS01585	COG1522	sequence-specific DNA binding
AX767_RS01590	COG0626	cystathionine gamma-synthase activity
AX767_RS01595	COG3181	Tripartite tricarboxylate transporter family receptor
AX767_RS01600	COG2072	flavoprotein involved in K transport
AX767_RS01615	COG0747	negative chemotaxis
AX767_RS01625	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AX767_RS01650	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AX767_RS01680	COG2188	Transcriptional regulator
AX767_RS01690	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AX767_RS01695	COG0066	3-isopropylmalate dehydratase activity
AX767_RS01705	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AX767_RS01725	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AX767_RS01730	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AX767_RS01750	COG2205	protein histidine kinase activity
AX767_RS01750	COG2202	Pas domain
AX767_RS01775	COG0583	DNA-binding transcription factor activity
AX767_RS01780	COG3181	Tripartite tricarboxylate transporter family receptor
AX767_RS01795	COG1294	oxidase, subunit
AX767_RS01800	COG1271	oxidase subunit
AX767_RS01805	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AX767_RS01810	COG4988	ABC transporter
AX767_RS01820	COG1960	acyl-CoA dehydrogenase activity
AX767_RS01835	COG0668	transmembrane transport
AX767_RS01845	COG0714	Associated with various cellular activities
AX767_RS01860	COG2951	lytic endotransglycosylase activity
AX767_RS01880	COG0395	ABC-type sugar transport system, permease component
AX767_RS01890	COG3842	ATPase activity
AX767_RS01895	COG3842	ATPase activity
AX767_RS01910	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AX767_RS01940	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
AX767_RS01945	COG2944	sequence-specific DNA binding
AX767_RS01950	COG2274	protein secretion by the type I secretion system
AX767_RS01960	COG2308	Evidence 4 Homologs of previously reported genes of
AX767_RS01980	COG1305	Transglutaminase-like
AX767_RS01990	COG1609	Transcriptional regulator
AX767_RS02000	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AX767_RS02010	COG1126	abc transporter atp-binding protein
AX767_RS02015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AX767_RS02020	COG0765	amino acid transport
AX767_RS02025	COG0765	amino acid transport
AX767_RS02040	COG0500	methyltransferase
AX767_RS02065	COG0739	heme binding
AX767_RS02065	COG0741	lytic transglycosylase activity
AX767_RS02065	COG1196	nuclear chromosome segregation
AX767_RS02085	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AX767_RS02090	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AX767_RS02095	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AX767_RS02110	COG2850	peptidyl-arginine hydroxylation
AX767_RS02115	COG1047	Peptidyl-prolyl cis-trans
AX767_RS02135	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AX767_RS02145	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AX767_RS02155	COG0148	phosphopyruvate hydratase activity
AX767_RS02160	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AX767_RS02165	COG3201	nicotinamide mononucleotide transporter
AX767_RS02175	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AX767_RS02185	COG2833	Protein of unknown function (DUF455)
AX767_RS02215	COG4974	Belongs to the 'phage' integrase family
AX767_RS02220	COG3181	Tripartite tricarboxylate transporter family receptor
AX767_RS02235	COG0802	atpase or kinase
AX767_RS02250	COG0586	Pfam SNARE associated Golgi protein
AX767_RS02255	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AX767_RS02270	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AX767_RS02275	COG4181	ATPase activity
AX767_RS02280	COG3395	kinase activity
AX767_RS02285	COG0235	Class ii aldolase
AX767_RS02345	COG0411	ABC transporter
AX767_RS02355	COG1566	PFAM secretion protein HlyD family protein
AX767_RS02365	COG1846	Transcriptional regulator
AX767_RS02370	COG1132	(ABC) transporter
AX767_RS02390	COG1007	ATP synthesis coupled electron transport
AX767_RS02405	COG0713	ATP synthesis coupled electron transport
AX767_RS02415	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AX767_RS02420	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AX767_RS02425	COG1034	ATP synthesis coupled electron transport
AX767_RS02435	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AX767_RS02440	COG0649	NAD binding
AX767_RS02445	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AX767_RS02450	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AX767_RS02455	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AX767_RS02470	COG0149	triose-phosphate isomerase activity
AX767_RS02475	COG0604	alcohol dehydrogenase
AX767_RS02475	COG1028	Short-chain dehydrogenase reductase Sdr
AX767_RS02475	COG3321	synthase
AX767_RS02480	COG1185	polyribonucleotide nucleotidyltransferase activity
AX767_RS02485	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AX767_RS02490	COG0436	Aminotransferase
AX767_RS02510	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AX767_RS02515	COG3707	response regulator
AX767_RS02520	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AX767_RS02530	COG0791	NLP P60 protein
AX767_RS02535	COG2081	HI0933 family
AX767_RS02540	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AX767_RS02545	COG1610	YqeY-like protein
AX767_RS02550	COG0312	modulator of DNA gyrase
AX767_RS02555	COG3028	Belongs to the UPF0307 family
AX767_RS02560	COG0521	Mo-molybdopterin cofactor biosynthetic process
AX767_RS02565	COG3916	Acyl-homoserine-lactone synthase
AX767_RS02585	COG1045	serine acetyltransferase
AX767_RS02595	COG0483	inositol monophosphate 1-phosphatase activity
AX767_RS02600	COG1289	transmembrane transporter activity
AX767_RS02610	COG1695	Transcriptional regulator
AX767_RS02615	COG2375	cellular response to nickel ion
AX767_RS02635	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AX767_RS02650	COG1968	undecaprenyl-diphosphatase activity
AX767_RS02665	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AX767_RS02670	COG1737	Transcriptional regulator
AX767_RS02690	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AX767_RS02710	COG3275	phosphorelay sensor kinase activity
AX767_RS02735	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AX767_RS02750	COG1280	lysine exporter protein (LysE YggA)
AX767_RS02800	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AX767_RS02810	COG1028	Short-chain dehydrogenase reductase Sdr
AX767_RS02815	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
AX767_RS02820	COG2918	glutathione biosynthetic process
AX767_RS02825	COG0400	carboxylic ester hydrolase activity
AX767_RS02835	COG0625	glutathione transferase activity
AX767_RS02880	COG2354	Protein conserved in bacteria
AX767_RS02890	COG4628	conserved protein (DUF2132)
AX767_RS02905	COG0564	pseudouridine synthase activity
AX767_RS02930	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AX767_RS02935	COG1252	NADH dehydrogenase
AX767_RS02965	COG0583	DNA-binding transcription factor activity
AX767_RS02970	COG0318	PFAM AMP-dependent synthetase and ligase
AX767_RS02975	COG1764	response to oxidative stress
AX767_RS02990	COG0765	amino acid transport
AX767_RS02995	COG0765	amino acid transport
AX767_RS03020	COG0584	glycerophosphoryl diester phosphodiesterase
AX767_RS03025	COG0789	Transcriptional regulator
AX767_RS03045	COG2132	Multicopper oxidase
AX767_RS03070	COG3191	aminopeptidase activity
AX767_RS03080	COG0488	(ABC) transporter
AX767_RS03085	COG0513	Belongs to the DEAD box helicase family
AX767_RS03090	COG1063	alcohol dehydrogenase
AX767_RS03095	COG1028	Short-chain dehydrogenase reductase Sdr
AX767_RS03100	COG3842	ATPase activity
AX767_RS03110	COG1175	transmembrane transport
AX767_RS03120	COG2186	Transcriptional regulator
AX767_RS03125	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AX767_RS03130	COG3734	2-keto-3-deoxy-galactonokinase
AX767_RS03135	COG0800	Aldolase
AX767_RS03140	COG0235	Class ii aldolase
AX767_RS03145	COG0683	leucine binding
AX767_RS03150	COG0559	Belongs to the binding-protein-dependent transport system permease family
AX767_RS03175	COG2186	Transcriptional regulator
AX767_RS03205	COG1840	ABC-type Fe3 transport system, periplasmic component
AX767_RS03220	COG0346	lactoylglutathione lyase activity
AX767_RS03235	COG0800	Aldolase
AX767_RS03260	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AX767_RS03260	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AX767_RS03265	COG0259	pyridoxamine-phosphate oxidase activity
AX767_RS03285	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AX767_RS03290	COG1309	transcriptional regulator
AX767_RS03305	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AX767_RS03335	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AX767_RS03340	COG0697	spore germination
AX767_RS03355	COG2863	cytochrome
AX767_RS03385	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AX767_RS03400	COG0277	FAD linked oxidase domain protein
AX767_RS03405	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AX767_RS03430	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AX767_RS03440	COG1136	(ABC) transporter
AX767_RS03450	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AX767_RS03480	COG0640	Transcriptional regulator
AX767_RS03520	COG3038	cytochrome b561
AX767_RS03535	COG2205	protein histidine kinase activity
AX767_RS03535	COG5002	protein histidine kinase activity
AX767_RS03535	COG0784	Response regulator, receiver
AX767_RS03540	COG0784	Response regulator, receiver
AX767_RS03545	COG0745	RESPONSE REGULATOR receiver
AX767_RS03555	COG2197	response regulator
AX767_RS03585	COG0542	response to heat
AX767_RS03595	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AX767_RS03600	COG1127	ABC transporter
AX767_RS03620	COG1902	pentaerythritol trinitrate reductase activity
AX767_RS03635	COG0783	Belongs to the Dps family
AX767_RS03640	COG4716	Myosin-crossreactive antigen
AX767_RS03645	COG0443	Heat shock 70 kDa protein
AX767_RS03665	COG0149	triose-phosphate isomerase activity
AX767_RS03675	COG3588	fructose-bisphosphate aldolase
AX767_RS03680	COG0406	alpha-ribazole phosphatase activity
AX767_RS03695	COG2130	NADP-dependent
AX767_RS03710	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AX767_RS03715	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AX767_RS03725	COG0356	it plays a direct role in the translocation of protons across the membrane
AX767_RS03745	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AX767_RS03750	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AX767_RS03765	COG0166	Belongs to the GPI family
AX767_RS03770	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AX767_RS03780	COG3387	PFAM Glycoside hydrolase 15-related
AX767_RS03790	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AX767_RS03795	COG3459	Glycosyltransferase 36 associated
AX767_RS03800	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
AX767_RS03820	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AX767_RS03820	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AX767_RS03845	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AX767_RS03855	COG1012	belongs to the aldehyde dehydrogenase family
AX767_RS03875	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AX767_RS03900	COG0285	dihydrofolate synthase activity
AX767_RS03905	COG1393	Belongs to the ArsC family
AX767_RS03915	COG3123	guanosine phosphorylase activity
AX767_RS03930	COG1666	GTP binding
AX767_RS03940	COG0251	oxidation-reduction process
AX767_RS03945	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AX767_RS03950	COG0667	Aldo Keto reductase
AX767_RS03980	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AX767_RS03990	COG2205	protein histidine kinase activity
AX767_RS03990	COG3850	Histidine kinase
AX767_RS03990	COG3437	response regulator, receiver
AX767_RS03990	COG4999	Histidine kinase
AX767_RS04000	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AX767_RS04010	COG0308	aminopeptidase N
AX767_RS04015	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AX767_RS04030	COG1960	acyl-CoA dehydrogenase activity
AX767_RS04035	COG0183	Belongs to the thiolase family
AX767_RS04045	COG1250	3-hydroxyacyl-CoA dehydrogenase
AX767_RS04045	COG1024	Enoyl-CoA hydratase
AX767_RS04070	COG2030	dehydratase
AX767_RS04100	COG1028	Short-chain dehydrogenase reductase Sdr
AX767_RS04105	COG2271	Major facilitator Superfamily
AX767_RS04110	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
AX767_RS04140	COG1253	flavin adenine dinucleotide binding
AX767_RS04150	COG0513	Belongs to the DEAD box helicase family
AX767_RS04155	COG2321	neutral zinc metallopeptidase
AX767_RS04165	COG0717	Belongs to the dCTP deaminase family
AX767_RS04170	COG0402	S-adenosylhomocysteine deaminase activity
AX767_RS04175	COG0318	PFAM AMP-dependent synthetase and ligase
AX767_RS04180	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AX767_RS04200	COG1079	Belongs to the binding-protein-dependent transport system permease family
AX767_RS04205	COG4603	Belongs to the binding-protein-dependent transport system permease family
AX767_RS04210	COG3845	ABC transporter
AX767_RS04220	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AX767_RS04265	COG2351	hydroxyisourate hydrolase activity
AX767_RS04270	COG2186	Transcriptional regulator
AX767_RS04285	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AX767_RS04290	COG0583	DNA-binding transcription factor activity
AX767_RS04295	COG2233	PERMEase
AX767_RS04300	COG1953	Uracil, thiamine, allantoin
AX767_RS04305	COG1301	dicarboxylic acid transport
AX767_RS04310	COG0628	permease
AX767_RS04315	COG0583	DNA-binding transcription factor activity
AX767_RS04320	COG3960	tartronate-semialdehyde synthase activity
AX767_RS04325	COG3622	Belongs to the hyi family
AX767_RS04330	COG2084	Dehydrogenase
AX767_RS04370	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AX767_RS04385	COG0217	transcriptional regulatory protein
AX767_RS04390	COG1902	pentaerythritol trinitrate reductase activity
AX767_RS04400	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AX767_RS04410	COG0791	NLP P60 protein
AX767_RS04415	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AX767_RS04430	COG0765	amino acid transport
AX767_RS04435	COG4597	amino acid ABC transporter
AX767_RS04445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AX767_RS04450	COG2721	sulfolactate sulfo-lyase activity
AX767_RS04460	COG1012	belongs to the aldehyde dehydrogenase family
AX767_RS04470	COG1129	ABC transporter
AX767_RS04475	COG1172	Belongs to the binding-protein-dependent transport system permease family
AX767_RS04480	COG1172	Belongs to the binding-protein-dependent transport system permease family
AX767_RS04490	COG0829	nickel cation binding
AX767_RS04510	COG1064	alcohol dehydrogenase
AX767_RS04520	COG0667	Aldo Keto reductase
AX767_RS04535	COG2814	Major facilitator Superfamily
AX767_RS04550	COG0765	amino acid transport
AX767_RS04555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AX767_RS04560	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AX767_RS04615	COG0613	PHP domain protein
AX767_RS04625	COG0009	L-threonylcarbamoyladenylate synthase
AX767_RS04630	COG1994	Peptidase M50
AX767_RS04635	COG0180	Tryptophanyl-tRNA synthetase
AX767_RS04640	COG2197	response regulator
AX767_RS04645	COG5002	protein histidine kinase activity
AX767_RS04655	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AX767_RS04660	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AX767_RS04665	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AX767_RS04670	COG1047	Peptidyl-prolyl cis-trans
AX767_RS04675	COG2003	Belongs to the UPF0758 family
AX767_RS04720	COG0243	molybdopterin cofactor binding
AX767_RS04720	COG3383	formate dehydrogenase (NAD+) activity
AX767_RS04725	COG3383	formate dehydrogenase (NAD+) activity
AX767_RS04725	COG0243	molybdopterin cofactor binding
AX767_RS04730	COG0437	4 iron, 4 sulfur cluster binding
AX767_RS04735	COG2864	formate dehydrogenase
AX767_RS04765	COG3276	selenocysteine insertion sequence binding
AX767_RS04785	COG2080	2 iron, 2 sulfur cluster binding
AX767_RS04790	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AX767_RS04795	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AX767_RS04815	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AX767_RS04820	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AX767_RS04825	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AX767_RS04830	COG3639	organic phosphonate transmembrane transporter activity
AX767_RS04840	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
AX767_RS04845	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AX767_RS04855	COG1028	Short-chain dehydrogenase reductase Sdr
AX767_RS04865	COG0243	molybdopterin cofactor binding
AX767_RS04870	COG2223	nitrite transmembrane transporter activity
AX767_RS04875	COG0583	DNA-binding transcription factor activity
AX767_RS04880	COG0489	protein tyrosine kinase activity
AX767_RS04890	COG3132	Protein of unknown function, DUF480
AX767_RS04895	COG0473	3-isopropylmalate dehydrogenase activity
AX767_RS04915	COG1028	Short-chain dehydrogenase reductase Sdr
AX767_RS04930	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AX767_RS04930	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AX767_RS04970	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AX767_RS04975	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AX767_RS04980	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AX767_RS04985	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AX767_RS04990	COG0588	phosphoglycerate mutase activity
AX767_RS04995	COG0793	Belongs to the peptidase S41A family
AX767_RS05000	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AX767_RS05005	COG2982	Protein involved in outer membrane biogenesis
AX767_RS05015	COG2197	response regulator
AX767_RS05020	COG4585	Histidine kinase
AX767_RS05030	COG2823	Periplasmic or secreted lipoprotein
AX767_RS05060	COG3568	Endonuclease Exonuclease Phosphatase
AX767_RS05070	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AX767_RS05090	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AX767_RS05105	COG2226	methyltransferase
AX767_RS05120	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AX767_RS05130	COG1175	transmembrane transport
AX767_RS05135	COG0395	ABC-type sugar transport system, permease component
AX767_RS05140	COG3842	ATPase activity
AX767_RS05145	COG0584	glycerophosphoryl diester phosphodiesterase
AX767_RS05150	COG3264	Mechanosensitive ion channel
AX767_RS05150	COG1196	nuclear chromosome segregation
AX767_RS05160	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AX767_RS05165	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AX767_RS05170	COG2890	protein-(glutamine-N5) methyltransferase activity
AX767_RS05175	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AX767_RS05185	COG0683	leucine binding
AX767_RS05190	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AX767_RS05195	COG1253	flavin adenine dinucleotide binding
AX767_RS05205	COG0442	prolyl-tRNA aminoacylation
AX767_RS05210	COG0494	nUDIX hydrolase
AX767_RS05220	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AX767_RS05225	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AX767_RS05230	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AX767_RS05235	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AX767_RS05240	COG0142	geranyltranstransferase activity
AX767_RS05270	COG1696	Membrane protein involved in D-alanine export
AX767_RS05285	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
AX767_RS05290	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AX767_RS05295	COG0494	nUDIX hydrolase
AX767_RS05305	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AX767_RS05310	COG0653	protein targeting
AX767_RS05320	COG0582	viral genome integration into host DNA
AX767_RS05385	COG2969	positive regulation of protein catabolic process
AX767_RS05390	COG0625	glutathione transferase activity
AX767_RS05395	COG2857	Cytochrome c1
AX767_RS05400	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AX767_RS05405	COG0723	plastoquinol--plastocyanin reductase activity
AX767_RS05410	COG1970	mechanosensitive ion channel activity
AX767_RS05415	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AX767_RS05420	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AX767_RS05430	COG0805	protein transport
AX767_RS05435	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AX767_RS05440	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AX767_RS05445	COG0537	adenosine 5'-monophosphoramidase activity
AX767_RS05455	COG0140	phosphoribosyl-ATP diphosphatase activity
AX767_RS05460	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AX767_RS05465	COG0107	imidazoleglycerol-phosphate synthase activity
AX767_RS05475	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AX767_RS05485	COG0131	Imidazoleglycerol-phosphate dehydratase
AX767_RS05490	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AX767_RS05500	COG0110	maltose O-acetyltransferase activity
AX767_RS05515	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AX767_RS05520	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AX767_RS05525	COG5007	Belongs to the BolA IbaG family
AX767_RS05530	COG0842	Transport permease protein
AX767_RS05535	COG1131	(ABC) transporter
AX767_RS05550	COG2853	Lipoprotein
AX767_RS05555	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AX767_RS05560	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AX767_RS05565	COG1127	ABC transporter
AX767_RS05575	COG0070	glutamate synthase
AX767_RS05575	COG0069	glutamate synthase activity
AX767_RS05575	COG0067	glutamate synthase
AX767_RS05600	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AX767_RS05605	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AX767_RS05610	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AX767_RS05645	COG1965	Belongs to the frataxin family
AX767_RS05655	COG0019	diaminopimelate decarboxylase activity
AX767_RS05660	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AX767_RS05665	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AX767_RS05670	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AX767_RS05675	COG1333	cytochrome c biogenesis protein
AX767_RS05685	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AX767_RS05690	COG2267	carboxylic ester hydrolase activity
AX767_RS05695	COG1560	Kdo2-lipid A biosynthetic process
AX767_RS05705	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AX767_RS05710	COG0683	leucine binding
AX767_RS05715	COG1172	Belongs to the binding-protein-dependent transport system permease family
AX767_RS05730	COG0410	ABC transporter
AX767_RS05735	COG4772	TonB-dependent receptor
AX767_RS05755	COG5002	protein histidine kinase activity
AX767_RS05755	COG5001	Diguanylate cyclase
AX767_RS05755	COG3447	MASE1 domain protein
AX767_RS05760	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AX767_RS05765	COG0459	protein refolding
AX767_RS05770	COG2207	Transcriptional regulator
AX767_RS05770	COG4753	response regulator
AX767_RS05780	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AX767_RS05790	COG0246	Mannitol dehydrogenase
AX767_RS05795	COG3842	ATPase activity
AX767_RS05800	COG0395	ABC-type sugar transport system, permease component
AX767_RS05805	COG1175	transmembrane transport
AX767_RS05820	COG0166	Belongs to the GPI family
AX767_RS05825	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AX767_RS05830	COG3040	lipid binding
AX767_RS05840	COG3842	ATPase activity
AX767_RS05850	COG1840	ABC-type Fe3 transport system, periplasmic component
AX767_RS05855	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AX767_RS05860	COG4608	Belongs to the ABC transporter superfamily
AX767_RS05865	COG0444	Belongs to the ABC transporter superfamily
AX767_RS05870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AX767_RS05875	COG4166	transmembrane transport
AX767_RS05880	COG1473	amidohydrolase
AX767_RS05895	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
AX767_RS05900	COG1765	OsmC-like protein
AX767_RS05905	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AX767_RS05975	COG0137	argininosuccinate synthase activity
AX767_RS05980	COG4178	(ABC) transporter
AX767_RS05990	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AX767_RS06005	COG1132	(ABC) transporter
AX767_RS06010	COG1181	Belongs to the D-alanine--D-alanine ligase family
AX767_RS06010	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AX767_RS06015	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AX767_RS06015	COG0189	ligase activity
AX767_RS06095	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AX767_RS06115	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AX767_RS06125	COG3639	organic phosphonate transmembrane transporter activity
AX767_RS06130	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AX767_RS06135	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AX767_RS06140	COG3454	Phosphonate metabolism
AX767_RS06145	COG4778	phosphonate C-P lyase system protein PhnL
AX767_RS06150	COG4107	phosphonate C-P lyase system protein PhnK
AX767_RS06155	COG3627	carbon phosphorus lyase activity
AX767_RS06160	COG3626	phosphonate metabolism
AX767_RS06170	COG3624	Phosphonate C-P lyase system protein PhnG
AX767_RS06175	COG1609	Transcriptional regulator
AX767_RS06180	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AX767_RS06185	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AX767_RS06195	COG1522	sequence-specific DNA binding
AX767_RS06200	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AX767_RS06210	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AX767_RS06225	COG0583	DNA-binding transcription factor activity
AX767_RS06230	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AX767_RS06235	COG0741	lytic transglycosylase activity
AX767_RS06245	COG1285	pathogenesis
AX767_RS06250	COG0625	glutathione transferase activity
AX767_RS06255	COG0617	tRNA 3'-terminal CCA addition
AX767_RS06265	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AX767_RS06270	COG0583	DNA-binding transcription factor activity
AX767_RS06310	COG1028	Short-chain dehydrogenase reductase Sdr
AX767_RS06320	COG0037	tRNA processing
AX767_RS06325	COG0038	chloride channel
AX767_RS06345	COG1116	anion transmembrane transporter activity
AX767_RS06350	COG0390	transport system, permease component
AX767_RS06355	COG0588	phosphoglycerate mutase activity
AX767_RS06365	COG1595	DNA-templated transcription, initiation
AX767_RS06390	COG3391	amine dehydrogenase activity
AX767_RS06425	COG0583	DNA-binding transcription factor activity
AX767_RS06430	COG0038	chloride channel
AX767_RS06470	COG0789	Transcriptional regulator
AX767_RS06520	COG0431	NADPH-dependent FMN reductase
AX767_RS06535	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AX767_RS06555	COG2217	Heavy metal translocating P-type atpase
AX767_RS06580	COG2132	Multicopper oxidase
AX767_RS06635	COG0037	tRNA processing
AX767_RS06645	COG0406	alpha-ribazole phosphatase activity
AX767_RS06690	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AX767_RS06695	COG2205	protein histidine kinase activity
AX767_RS06705	COG2204	response regulator
AX767_RS06715	COG2943	transferase activity, transferring hexosyl groups
AX767_RS06720	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AX767_RS06750	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AX767_RS06750	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AX767_RS06755	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AX767_RS06765	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AX767_RS06775	COG2264	protein methyltransferase activity
AX767_RS06780	COG0439	Biotin carboxylase
AX767_RS06785	COG0511	ligase activity, forming carbon-carbon bonds
AX767_RS06790	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AX767_RS06800	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AX767_RS06810	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AX767_RS06815	COG0312	modulator of DNA gyrase
AX767_RS06820	COG0772	Belongs to the SEDS family
AX767_RS06830	COG2197	response regulator
AX767_RS06840	COG3150	esterase
AX767_RS06855	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AX767_RS06870	COG4589	Belongs to the CDS family
AX767_RS06875	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AX767_RS06885	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AX767_RS06890	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AX767_RS06900	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AX767_RS06905	COG1181	Belongs to the D-alanine--D-alanine ligase family
AX767_RS06910	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AX767_RS06915	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AX767_RS06920	COG0772	Belongs to the SEDS family
AX767_RS06925	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AX767_RS06930	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AX767_RS06935	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AX767_RS06940	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AX767_RS06950	COG3116	cell division
AX767_RS06955	COG0275	rRNA processing
AX767_RS06960	COG2001	Belongs to the MraZ family
AX767_RS06965	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AX767_RS06970	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AX767_RS06985	COG0523	cobalamin synthesis protein
AX767_RS06995	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AX767_RS07010	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AX767_RS07030	COG0583	DNA-binding transcription factor activity
AX767_RS07035	COG2814	Major facilitator Superfamily
AX767_RS07040	COG0656	L-ascorbic acid biosynthetic process
AX767_RS07055	COG1802	Transcriptional regulator
AX767_RS07060	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AX767_RS07065	COG0444	Belongs to the ABC transporter superfamily
AX767_RS07070	COG4608	Belongs to the ABC transporter superfamily
AX767_RS07090	COG0318	PFAM AMP-dependent synthetase and ligase
AX767_RS07095	COG0318	PFAM AMP-dependent synthetase and ligase
AX767_RS07100	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AX767_RS07105	COG0508	dehydrogenase complex catalyzes the overall conversion of
AX767_RS07130	COG0745	RESPONSE REGULATOR receiver
AX767_RS07135	COG0642	Histidine kinase
AX767_RS07160	COG1275	C4-dicarboxylate transporter malic acid transport protein
AX767_RS07170	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
AX767_RS07180	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AX767_RS07190	COG0501	Belongs to the peptidase M48B family
AX767_RS07205	COG0418	dihydroorotase activity
AX767_RS07220	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AX767_RS07220	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AX767_RS07225	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AX767_RS07230	COG1126	abc transporter atp-binding protein
AX767_RS07235	COG0765	amino acid transport
AX767_RS07240	COG0765	amino acid transport
AX767_RS07250	COG0583	DNA-binding transcription factor activity
AX767_RS07255	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AX767_RS07260	COG5265	(ABC) transporter
AX767_RS07270	COG0251	oxidation-reduction process
AX767_RS07280	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AX767_RS07300	COG0183	Belongs to the thiolase family
AX767_RS07305	COG1024	Enoyl-CoA hydratase
AX767_RS07305	COG1250	3-hydroxyacyl-CoA dehydrogenase
AX767_RS07315	COG1960	acyl-CoA dehydrogenase activity
AX767_RS07330	COG2133	pyrroloquinoline quinone binding
AX767_RS07345	COG1028	Short-chain dehydrogenase reductase Sdr
AX767_RS07350	COG1028	Short-chain dehydrogenase reductase Sdr
AX767_RS07355	COG2186	Transcriptional regulator
AX767_RS07360	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AX767_RS07370	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AX767_RS07375	COG2721	sulfolactate sulfo-lyase activity
AX767_RS07380	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AX767_RS07385	COG1309	transcriptional regulator
AX767_RS07390	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AX767_RS07405	COG1215	transferase activity, transferring glycosyl groups
AX767_RS07410	COG0438	transferase activity, transferring glycosyl groups
AX767_RS07410	COG1216	Glycosyl transferase, family 2
AX767_RS07415	COG2755	lipolytic protein G-D-S-L family
AX767_RS07415	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AX767_RS07445	COG2433	Pfam Transposase IS66
AX767_RS07475	COG1053	succinate dehydrogenase
AX767_RS07475	COG0431	NADPH-dependent FMN reductase
AX767_RS07475	COG3976	FMN-binding domain protein
AX767_RS07505	COG0546	phosphoglycolate phosphatase activity
AX767_RS07505	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AX767_RS07510	COG1216	Glycosyl transferase, family 2
AX767_RS07510	COG0438	transferase activity, transferring glycosyl groups
AX767_RS07535	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
AX767_RS07535	COG0662	Cupin 2, conserved barrel domain protein
AX767_RS07540	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
AX767_RS07575	COG0243	molybdopterin cofactor binding
AX767_RS07590	COG2733	membrane
AX767_RS07600	COG0584	glycerophosphoryl diester phosphodiesterase
AX767_RS07605	COG1473	amidohydrolase
AX767_RS07615	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AX767_RS07640	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AX767_RS07655	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AX767_RS07665	COG1131	(ABC) transporter
AX767_RS07670	COG0842	Transport permease protein
AX767_RS07685	COG0513	Belongs to the DEAD box helicase family
AX767_RS07690	COG0023	Translation Initiation Factor
AX767_RS07700	COG0724	RNA recognition motif
AX767_RS07705	COG0657	acetylesterase activity
AX767_RS07710	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AX767_RS07715	COG1250	3-hydroxyacyl-CoA dehydrogenase
AX767_RS07720	COG1024	Enoyl-CoA hydratase
AX767_RS07730	COG1846	Transcriptional regulator
AX767_RS07735	COG1764	response to oxidative stress
AX767_RS07745	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AX767_RS07755	COG0326	Molecular chaperone. Has ATPase activity
AX767_RS07785	COG1840	ABC-type Fe3 transport system, periplasmic component
AX767_RS07790	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AX767_RS07800	COG0642	Histidine kinase
AX767_RS07810	COG1187	pseudouridine synthase activity
AX767_RS07815	COG1056	cytidyltransferase-related domain
AX767_RS07815	COG1051	belongs to the nudix hydrolase family
AX767_RS07845	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AX767_RS07865	COG1360	Flagellar Motor Protein
AX767_RS07880	COG0745	RESPONSE REGULATOR receiver
AX767_RS07885	COG2205	protein histidine kinase activity
AX767_RS07900	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AX767_RS07905	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AX767_RS07910	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AX767_RS07940	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AX767_RS07975	COG0318	PFAM AMP-dependent synthetase and ligase
AX767_RS07980	COG1028	Short-chain dehydrogenase reductase Sdr
AX767_RS08005	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AX767_RS08010	COG0022	dehydrogenase e1 component
AX767_RS08030	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AX767_RS08045	COG1024	Enoyl-CoA hydratase
AX767_RS08050	COG1960	acyl-CoA dehydrogenase activity
AX767_RS08060	COG0251	oxidation-reduction process
AX767_RS08070	COG0203	ribosomal protein L17
AX767_RS08075	COG0202	RNA polymerase activity
AX767_RS08080	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AX767_RS08085	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AX767_RS08090	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AX767_RS08095	COG0201	protein transport
AX767_RS08100	COG0200	Binds to the 23S rRNA
AX767_RS08105	COG1841	ribosomal large subunit assembly
AX767_RS08110	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AX767_RS08115	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AX767_RS08120	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AX767_RS08125	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AX767_RS08130	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AX767_RS08135	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AX767_RS08140	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AX767_RS08145	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AX767_RS08160	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AX767_RS08165	COG0783	Belongs to the Dps family
AX767_RS08175	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AX767_RS08180	COG1090	epimerase
AX767_RS08185	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AX767_RS08195	COG0343	queuine tRNA-ribosyltransferase activity
AX767_RS08220	COG0671	phosphoesterase, PA-phosphatase related
AX767_RS08245	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AX767_RS08300	COG2095	MarC family integral membrane protein
AX767_RS08330	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AX767_RS08340	COG0277	FAD linked oxidase domain protein
AX767_RS08345	COG1380	Effector of murein hydrolase LrgA
AX767_RS08350	COG1346	cytolysis
AX767_RS08365	COG0439	Biotin carboxylase
AX767_RS08370	COG0318	PFAM AMP-dependent synthetase and ligase
AX767_RS08380	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AX767_RS08380	COG2124	cytochrome p450
AX767_RS08385	COG1971	Probably functions as a manganese efflux pump
AX767_RS08390	COG2194	sulfuric ester hydrolase activity
AX767_RS08435	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AX767_RS08455	COG0583	DNA-binding transcription factor activity
AX767_RS08460	COG1960	acyl-CoA dehydrogenase activity
AX767_RS08465	COG3181	Tripartite tricarboxylate transporter family receptor
AX767_RS08485	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AX767_RS08515	COG2084	Dehydrogenase
AX767_RS08525	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AX767_RS08530	COG0792	nuclease activity
AX767_RS08535	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AX767_RS08550	COG1309	transcriptional regulator
AX767_RS08555	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AX767_RS08560	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AX767_RS08620	COG1201	RNA secondary structure unwinding
AX767_RS08635	COG1793	dna ligase
AX767_RS08640	COG1793	dna ligase
AX767_RS08640	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AX767_RS08660	COG0673	inositol 2-dehydrogenase activity
AX767_RS08665	COG1879	ABC-type sugar transport system periplasmic component
AX767_RS08670	COG1172	Belongs to the binding-protein-dependent transport system permease family
AX767_RS08680	COG1940	carbohydrate kinase activity
AX767_RS08685	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AX767_RS08690	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AX767_RS08695	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AX767_RS08700	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AX767_RS08705	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AX767_RS08710	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AX767_RS08720	COG0356	it plays a direct role in the translocation of protons across the membrane
AX767_RS08730	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AX767_RS08735	COG2921	Belongs to the UPF0250 family
AX767_RS08740	COG0321	lipoyl(octanoyl) transferase activity
AX767_RS08745	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AX767_RS08750	COG0602	queuosine metabolic process
AX767_RS08760	COG0318	PFAM AMP-dependent synthetase and ligase
AX767_RS08765	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AX767_RS08840	COG0625	glutathione transferase activity
AX767_RS08860	COG2130	NADP-dependent
AX767_RS08870	COG3850	Histidine kinase
AX767_RS08870	COG5002	protein histidine kinase activity
AX767_RS08875	COG0745	RESPONSE REGULATOR receiver
AX767_RS08885	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AX767_RS08890	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AX767_RS08905	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AX767_RS08910	COG0456	acetyltransferase
AX767_RS08915	COG0678	peroxiredoxin activity
AX767_RS08920	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AX767_RS08925	COG0255	Belongs to the universal ribosomal protein uL29 family
AX767_RS08930	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AX767_RS08935	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AX767_RS08940	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AX767_RS08945	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AX767_RS08950	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AX767_RS08955	COG0089	rRNA binding
AX767_RS08960	COG0088	Forms part of the polypeptide exit tunnel
AX767_RS08965	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AX767_RS08970	COG0051	transcription antitermination factor activity, RNA binding
AX767_RS08975	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AX767_RS08980	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AX767_RS08985	COG0049	tRNA binding
AX767_RS08990	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AX767_RS08995	COG1686	Belongs to the peptidase S11 family
AX767_RS09000	COG2945	thiolester hydrolase activity
AX767_RS09005	COG3411	Ferredoxin
AX767_RS09015	COG1981	membrane
AX767_RS09025	COG0598	Magnesium transport protein CorA
AX767_RS09035	COG0583	DNA-binding transcription factor activity
AX767_RS09045	COG0412	Dienelactone hydrolase
AX767_RS09055	COG1028	Short-chain dehydrogenase reductase Sdr
AX767_RS09060	COG2095	MarC family integral membrane protein
AX767_RS09065	COG0583	DNA-binding transcription factor activity
AX767_RS09070	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AX767_RS09075	COG3002	Belongs to the UPF0753 family
AX767_RS09110	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AX767_RS09115	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AX767_RS09145	COG0768	penicillin binding
AX767_RS09155	COG1792	Involved in formation and maintenance of cell shape
AX767_RS09160	COG1077	Cell shape determining protein MreB Mrl
AX767_RS09165	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AX767_RS09170	COG0154	amidase activity
AX767_RS09175	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AX767_RS09185	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AX767_RS09190	COG0708	Exodeoxyribonuclease III
AX767_RS09235	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AX767_RS09240	COG0300	oxidoreductase activity
AX767_RS09245	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AX767_RS09250	COG1335	isochorismatase
AX767_RS09280	COG3845	ABC transporter
AX767_RS09290	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AX767_RS09295	COG1079	Belongs to the binding-protein-dependent transport system permease family
AX767_RS09330	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AX767_RS09355	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AX767_RS09365	COG0579	oxidoreductase
AX767_RS09370	COG0745	RESPONSE REGULATOR receiver
AX767_RS09385	COG0463	Glycosyl transferase, family 2
AX767_RS09390	COG0110	maltose O-acetyltransferase activity
AX767_RS09405	COG0463	Glycosyl transferase, family 2
AX767_RS09410	COG2974	May be involved in recombination
AX767_RS09420	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AX767_RS09435	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AX767_RS09440	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AX767_RS09445	COG0477	Major facilitator Superfamily
AX767_RS09450	COG0386	Belongs to the glutathione peroxidase family
AX767_RS09465	COG5295	Hep Hag repeat protein
AX767_RS09465	COG5295	Hep Hag repeat protein
AX767_RS09485	COG5295	Hep Hag repeat protein
AX767_RS09495	COG2205	protein histidine kinase activity
AX767_RS09510	COG0247	lactate metabolic process
AX767_RS09515	COG0277	FAD linked oxidase domain protein
AX767_RS09525	COG0004	ammonium transporteR
AX767_RS09530	COG0347	Belongs to the P(II) protein family
AX767_RS09580	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AX767_RS09600	COG2194	sulfuric ester hydrolase activity
AX767_RS09610	COG5002	protein histidine kinase activity
AX767_RS09640	COG0789	Transcriptional regulator
AX767_RS09645	COG1285	pathogenesis
AX767_RS09650	COG4993	Dehydrogenase
AX767_RS09655	COG4993	Dehydrogenase
AX767_RS09675	COG0606	chelatase, subunit chli
AX767_RS09685	COG2885	chlorophyll binding
AX767_RS09735	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AX767_RS09735	COG2010	Cytochrome c
AX767_RS09740	COG2080	2 iron, 2 sulfur cluster binding
AX767_RS09745	COG1335	isochorismatase
AX767_RS09795	COG1309	transcriptional regulator
AX767_RS09830	COG4796	Type ii and iii secretion system protein
AX767_RS09870	COG0741	lytic transglycosylase activity
AX767_RS09895	COG1410	methionine synthase
AX767_RS09895	COG0646	methionine synthase
AX767_RS09900	COG1199	ATP-dependent helicase activity
AX767_RS09935	COG1228	amidohydrolase
AX767_RS09945	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AX767_RS09950	COG2986	histidine ammonia-lyase
AX767_RS09965	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AX767_RS09975	COG0514	ATP-dependent DNA helicase (RecQ)
AX767_RS09985	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AX767_RS09990	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
AX767_RS10015	COG3540	Alkaline phosphatase
AX767_RS10020	COG1295	ribonuclease BN
AX767_RS10025	COG3276	selenocysteine insertion sequence binding
AX767_RS10045	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AX767_RS10050	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AX767_RS10055	COG0700	Nucleoside recognition
AX767_RS10060	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AX767_RS10070	COG2066	Belongs to the glutaminase family
AX767_RS10095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AX767_RS10105	COG2267	carboxylic ester hydrolase activity
AX767_RS10115	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AX767_RS10120	COG1960	acyl-CoA dehydrogenase activity
AX767_RS10125	COG0583	DNA-binding transcription factor activity
AX767_RS10135	COG2721	sulfolactate sulfo-lyase activity
AX767_RS10155	COG5295	Hep Hag repeat protein
AX767_RS10155	COG5295	Hep Hag repeat protein
AX767_RS10160	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AX767_RS10165	COG0625	glutathione transferase activity
AX767_RS10175	COG2050	protein possibly involved in aromatic compounds catabolism
AX767_RS10180	COG2233	PERMEase
AX767_RS10190	COG0850	regulation of cytokinetic process
AX767_RS10195	COG2894	cell division
AX767_RS10200	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AX767_RS10215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AX767_RS10225	COG2096	Adenosyltransferase
AX767_RS10230	COG0277	FAD linked oxidase domain protein
AX767_RS10240	COG1475	DNA binding
AX767_RS10250	COG1192	Involved in chromosome partitioning
AX767_RS10265	COG0357	Ribosomal RNA small subunit methyltransferase G
AX767_RS10270	COG0445	tRNA wobble uridine modification
AX767_RS10280	COG5487	UPF0391 membrane protein
AX767_RS10290	COG3046	protein related to deoxyribodipyrimidine photolyase
AX767_RS10300	COG1028	Short-chain dehydrogenase reductase Sdr
AX767_RS10305	COG1902	pentaerythritol trinitrate reductase activity
AX767_RS10310	COG0642	Histidine kinase
AX767_RS10315	COG0745	RESPONSE REGULATOR receiver
AX767_RS10340	COG0667	Aldo Keto reductase
AX767_RS10345	COG3550	peptidyl-serine autophosphorylation
AX767_RS10350	COG2217	Heavy metal translocating P-type atpase
AX767_RS10355	COG2217	Heavy metal translocating P-type atpase
AX767_RS10360	COG0789	Transcriptional regulator
AX767_RS10365	COG0745	RESPONSE REGULATOR receiver
AX767_RS10370	COG2205	protein histidine kinase activity
AX767_RS10380	COG4452	Inner membrane protein CreD
AX767_RS10400	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AX767_RS10405	COG0456	acetyltransferase
AX767_RS10410	COG3842	ATPase activity
AX767_RS10420	COG1176	ABC-type spermidine putrescine transport system, permease component I
AX767_RS10425	COG3833	ABC-type maltose transport systems, permease component
AX767_RS10445	COG3568	Endonuclease Exonuclease Phosphatase
AX767_RS10455	COG0392	lysyltransferase activity
AX767_RS10460	COG4948	Mandelate Racemase Muconate Lactonizing
AX767_RS10470	COG2084	Dehydrogenase
AX767_RS10490	COG1408	metallophosphoesterase
AX767_RS10500	COG0598	Magnesium transport protein CorA
AX767_RS10515	COG0589	response to stress
AX767_RS10520	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AX767_RS10540	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AX767_RS10545	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AX767_RS10550	COG0594	ribonuclease P activity
AX767_RS10555	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AX767_RS10560	COG0706	membrane insertase activity
AX767_RS10565	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AX767_RS10595	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AX767_RS10605	COG0300	oxidoreductase activity
AX767_RS10610	COG0724	RNA recognition motif
AX767_RS10615	COG2119	membrane
AX767_RS10620	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AX767_RS10625	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AX767_RS10630	COG3622	Belongs to the hyi family
AX767_RS10635	COG1739	Uncharacterized protein family UPF0029
AX767_RS10640	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AX767_RS10660	COG2814	Major facilitator Superfamily
AX767_RS10665	COG3753	Protein conserved in bacteria
AX767_RS10675	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AX767_RS10685	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AX767_RS10690	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AX767_RS10695	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AX767_RS10730	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AX767_RS10750	COG0006	proline dipeptidase activity
AX767_RS10760	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AX767_RS10765	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AX767_RS10770	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AX767_RS10775	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AX767_RS10780	COG1914	H( )-stimulated, divalent metal cation uptake system
AX767_RS10785	COG2900	Belongs to the SlyX family
AX767_RS10795	COG1295	ribonuclease BN
AX767_RS10800	COG2201	protein-glutamate methylesterase activity
AX767_RS10835	COG0210	DNA helicase
AX767_RS10885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AX767_RS10890	COG0765	amino acid transport
AX767_RS10895	COG1126	abc transporter atp-binding protein
AX767_RS10900	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AX767_RS10905	COG0154	amidase activity
AX767_RS10920	COG0783	Belongs to the Dps family
AX767_RS10945	COG0513	Belongs to the DEAD box helicase family
AX767_RS10950	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AX767_RS10960	COG1070	Carbohydrate kinase
AX767_RS10965	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AX767_RS10985	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AX767_RS10985	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AX767_RS10995	COG0642	Histidine kinase
AX767_RS11010	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AX767_RS11015	COG2137	regulation of response to DNA damage stimulus
AX767_RS11025	COG1446	asparaginase
AX767_RS11030	COG4172	Belongs to the ABC transporter superfamily
AX767_RS11035	COG0747	negative chemotaxis
AX767_RS11055	COG4682	membrane
AX767_RS11060	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AX767_RS11065	COG0045	succinate-CoA ligase (ADP-forming) activity
AX767_RS11070	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AX767_RS11075	COG0861	Integral membrane protein TerC family
AX767_RS11080	COG0631	protein serine/threonine phosphatase activity
AX767_RS11150	COG0315	cyclic pyranopterin monophosphate synthase activity
AX767_RS11155	COG4783	chaperone-mediated protein folding
AX767_RS11160	COG1950	PFAM Membrane protein of
AX767_RS11170	COG0861	Integral membrane protein TerC family
AX767_RS11200	COG4269	membrane
AX767_RS11205	COG0625	glutathione transferase activity
AX767_RS11230	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AX767_RS11260	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AX767_RS11275	COG4566	intracellular signal transduction
AX767_RS11305	COG2084	Dehydrogenase
AX767_RS11310	COG2814	Major facilitator Superfamily
AX767_RS11315	COG1522	sequence-specific DNA binding
AX767_RS11325	COG1862	Preprotein translocase
AX767_RS11330	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AX767_RS11335	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AX767_RS11345	COG2922	Belongs to the Smg family
AX767_RS11350	COG0758	DNA mediated transformation
AX767_RS11360	COG0242	peptide deformylase activity
AX767_RS11370	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AX767_RS11385	COG0126	phosphoglycerate kinase activity
AX767_RS11395	COG0469	pyruvate kinase activity
AX767_RS11405	COG3588	fructose-bisphosphate aldolase
AX767_RS11410	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AX767_RS11450	COG3118	belongs to the thioredoxin family
AX767_RS11455	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AX767_RS11460	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AX767_RS11465	COG0009	L-threonylcarbamoyladenylate synthase
AX767_RS11470	COG2027	D-alanyl-D-alanine carboxypeptidase
AX767_RS11495	COG0284	orotidine-5'-phosphate decarboxylase activity
AX767_RS11515	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AX767_RS11525	COG0179	Fumarylacetoacetate (FAA) hydrolase
AX767_RS11545	COG0446	pyridine nucleotide-disulphide oxidoreductase
AX767_RS11555	COG1946	Acyl-CoA thioesterase
AX767_RS11585	COG0697	spore germination
AX767_RS11595	COG1228	amidohydrolase
AX767_RS11605	COG4608	Belongs to the ABC transporter superfamily
AX767_RS11610	COG0444	Belongs to the ABC transporter superfamily
AX767_RS11615	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AX767_RS11620	COG0601	transmembrane transport
AX767_RS11630	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AX767_RS11640	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AX767_RS11645	COG5002	protein histidine kinase activity
AX767_RS11650	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AX767_RS11655	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AX767_RS11660	COG4521	taurine ABC transporter
AX767_RS11675	COG0629	single-stranded DNA binding
AX767_RS11690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AX767_RS11695	COG0517	IMP dehydrogenase activity
AX767_RS11700	COG0482	sulfurtransferase activity
AX767_RS11705	COG0318	PFAM AMP-dependent synthetase and ligase
AX767_RS11720	COG0642	Histidine kinase
AX767_RS11730	COG0745	RESPONSE REGULATOR receiver
AX767_RS11750	COG0318	PFAM AMP-dependent synthetase and ligase
AX767_RS11765	COG0598	Magnesium transport protein CorA
AX767_RS11775	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AX767_RS11785	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AX767_RS11790	COG0735	belongs to the Fur family
AX767_RS11795	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AX767_RS11800	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AX767_RS11815	COG0058	SHG alpha-glucan phosphorylase activity
AX767_RS11820	COG0297	glycogen (starch) synthase activity
AX767_RS11825	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AX767_RS11830	COG1523	belongs to the glycosyl hydrolase 13 family
AX767_RS11835	COG4115	mRNA cleavage
AX767_RS11840	COG2161	toxin-antitoxin pair type II binding
AX767_RS11845	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AX767_RS11850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AX767_RS11855	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AX767_RS11865	COG0495	leucyl-tRNA aminoacylation
AX767_RS11900	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AX767_RS11910	COG3158	transport of potassium into the cell
AX767_RS11925	COG3135	benzoate transporter
AX767_RS11930	COG0189	ligase activity
AX767_RS11945	COG0121	glutamine amidotransferase
AX767_RS11950	COG2814	Major facilitator Superfamily
AX767_RS11965	COG0205	6-phosphofructokinase activity
AX767_RS11975	COG1024	Enoyl-CoA hydratase
AX767_RS11980	COG0183	Belongs to the thiolase family
AX767_RS11985	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AX767_RS12000	COG1256	bacterial-type flagellum assembly
AX767_RS12000	COG4786	Flagellar basal body rod
AX767_RS12005	COG3951	Flagellar rod assembly protein muramidase FlgJ
AX767_RS12005	COG1705	Flagellar rod assembly protein muramidase FlgJ
AX767_RS12010	COG1706	bacterial-type flagellum-dependent cell motility
AX767_RS12015	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AX767_RS12025	COG4787	bacterial-type flagellum-dependent cell motility
AX767_RS12035	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AX767_RS12040	COG1558	bacterial-type flagellum-dependent cell motility
AX767_RS12045	COG1815	bacterial-type flagellum-dependent cell motility
AX767_RS12125	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AX767_RS12130	COG5001	Diguanylate cyclase
AX767_RS12130	COG5002	protein histidine kinase activity
AX767_RS12130	COG3447	MASE1 domain protein
AX767_RS12135	COG2200	EAL domain
AX767_RS12185	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AX767_RS12215	COG2197	response regulator
AX767_RS12220	COG4585	Histidine kinase
AX767_RS12230	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AX767_RS12235	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AX767_RS12240	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AX767_RS12245	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AX767_RS12265	COG0018	arginyl-trna synthetase
AX767_RS12275	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AX767_RS12285	COG1137	ATPase activity
AX767_RS12290	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AX767_RS12310	COG0069	glutamate synthase activity
AX767_RS12315	COG3012	SEC-C Motif Domain Protein
AX767_RS12315	COG3318	Belongs to the UPF0149 family
AX767_RS12320	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
AX767_RS12335	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AX767_RS12340	COG1845	cytochrome c oxidase, subunit III
AX767_RS12345	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AX767_RS12350	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AX767_RS12355	COG0477	Major facilitator Superfamily
AX767_RS12385	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AX767_RS12395	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AX767_RS12410	COG2967	ApaG domain
AX767_RS12415	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AX767_RS12485	COG2203	Gaf domain
AX767_RS12485	COG2199	diguanylate cyclase activity
AX767_RS12500	COG2205	protein histidine kinase activity
AX767_RS12510	COG2198	Histidine kinase
AX767_RS12510	COG0784	Response regulator, receiver
AX767_RS12510	COG2205	protein histidine kinase activity
AX767_RS12515	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AX767_RS12540	COG0515	serine threonine protein kinase
AX767_RS12675	COG0546	phosphoglycolate phosphatase activity
AX767_RS12690	COG0512	Glutamine amidotransferase of anthranilate synthase
AX767_RS12700	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AX767_RS12705	COG0134	indole-3-glycerol-phosphate synthase activity
AX767_RS12710	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AX767_RS12735	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AX767_RS12745	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AX767_RS12755	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AX767_RS12760	COG0081	regulation of translation
AX767_RS12765	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AX767_RS12770	COG0222	ribosome binding
AX767_RS12775	COG0085	RNA polymerase activity
AX767_RS12780	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AX767_RS12800	COG5000	phosphorelay sensor kinase activity
AX767_RS12805	COG2204	response regulator
AX767_RS12815	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AX767_RS12835	COG0210	DNA helicase
AX767_RS12840	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AX767_RS12850	COG0679	Auxin Efflux Carrier
AX767_RS12875	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AX767_RS12880	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AX767_RS12890	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AX767_RS12895	COG4232	protein-disulfide reductase activity
AX767_RS12920	COG0583	DNA-binding transcription factor activity
AX767_RS12925	COG0670	Belongs to the BI1 family
AX767_RS12940	COG1028	Short-chain dehydrogenase reductase Sdr
AX767_RS12960	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AX767_RS12990	COG3468	outer membrane autotransporter barrel domain protein
AX767_RS12995	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AX767_RS13005	COG0129	dihydroxy-acid dehydratase activity
AX767_RS13020	COG0395	ABC-type sugar transport system, permease component
AX767_RS13025	COG3842	ATPase activity
AX767_RS13050	COG0384	phenazine biosynthesis protein PhzF
AX767_RS13055	COG0625	glutathione transferase activity
AX767_RS13060	COG1280	lysine exporter protein (LysE YggA)
AX767_RS13065	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AX767_RS13085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AX767_RS13090	COG0488	(ABC) transporter
AX767_RS13130	COG2433	Pfam Transposase IS66
AX767_RS13140	COG0318	PFAM AMP-dependent synthetase and ligase
AX767_RS13155	COG4535	Mg2 and Co2 transporter CorC
AX767_RS13160	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AX767_RS13170	COG0671	phosphoesterase, PA-phosphatase related
AX767_RS13180	COG1597	lipid kinase activity
AX767_RS13185	COG0752	glycyl-tRNA synthetase alpha subunit
AX767_RS13190	COG0751	glycine-tRNA ligase activity
AX767_RS13195	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AX767_RS13235	COG0789	Transcriptional regulator
AX767_RS13240	COG0288	reversible hydration of carbon dioxide
AX767_RS13245	COG0183	Belongs to the thiolase family
AX767_RS13255	COG1960	acyl-CoA dehydrogenase activity
AX767_RS13265	COG3012	SEC-C Motif Domain Protein
AX767_RS13270	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AX767_RS13275	COG2197	response regulator
AX767_RS13295	COG1960	acyl-CoA dehydrogenase activity
AX767_RS13300	COG0318	PFAM AMP-dependent synthetase and ligase
AX767_RS13310	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AX767_RS13320	COG1024	Enoyl-CoA hydratase
AX767_RS13340	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AX767_RS13365	COG0477	Major facilitator Superfamily
AX767_RS13370	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AX767_RS13380	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AX767_RS13385	COG0732	type I restriction modification DNA specificity domain
AX767_RS13405	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AX767_RS13430	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AX767_RS13445	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AX767_RS13455	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AX767_RS13460	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AX767_RS13465	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AX767_RS13470	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AX767_RS13475	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AX767_RS13480	COG0316	Belongs to the HesB IscA family
AX767_RS13485	COG2814	Major facilitator Superfamily
AX767_RS13490	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AX767_RS13495	COG0739	heme binding
AX767_RS13500	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AX767_RS13515	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AX767_RS13520	COG1490	D-aminoacyl-tRNA deacylase activity
AX767_RS13525	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AX767_RS13530	COG1702	phosphate starvation-inducible protein PhoH
AX767_RS13535	COG0632	four-way junction helicase activity
AX767_RS13550	COG2255	four-way junction helicase activity
AX767_RS13595	COG1024	Enoyl-CoA hydratase
AX767_RS13610	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AX767_RS13615	COG0633	Ferredoxin
AX767_RS13615	COG3217	Mosc domain protein beta barrel domain protein
AX767_RS13620	COG1869	D-ribose catabolic process
AX767_RS13625	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AX767_RS13630	COG1609	Transcriptional regulator
AX767_RS13635	COG1172	Belongs to the binding-protein-dependent transport system permease family
AX767_RS13640	COG1129	ABC transporter
AX767_RS13645	COG1879	ABC-type sugar transport system periplasmic component
AX767_RS13650	COG0012	GTP binding
AX767_RS13660	COG1238	metal cluster binding
AX767_RS13665	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AX767_RS13670	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AX767_RS13675	COG0138	bifunctional purine biosynthesis protein purh
AX767_RS13685	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AX767_RS13690	COG0352	thiamine-phosphate diphosphorylase activity
AX767_RS13690	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AX767_RS13690	COG0351	phosphomethylpyrimidine kinase
AX767_RS13695	COG1773	rubredoxin
AX767_RS13720	COG2198	Histidine kinase
AX767_RS13720	COG0784	Response regulator, receiver
AX767_RS13720	COG0643	Histidine kinase
AX767_RS13725	COG0415	Belongs to the DNA photolyase family
AX767_RS13730	COG1678	Uncharacterized ACR, COG1678
AX767_RS13735	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AX767_RS13740	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AX767_RS13745	COG0540	Belongs to the ATCase OTCase family
AX767_RS13760	COG1051	belongs to the nudix hydrolase family
AX767_RS13760	COG1056	cytidyltransferase-related domain
AX767_RS13800	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AX767_RS13810	COG3485	protocatechuate 3,4-dioxygenase
AX767_RS13815	COG3485	protocatechuate 3,4-dioxygenase
AX767_RS13820	COG0583	DNA-binding transcription factor activity
AX767_RS13835	COG1414	Transcriptional regulator
AX767_RS13845	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AX767_RS13850	COG0183	Belongs to the thiolase family
AX767_RS13880	COG1028	Short-chain dehydrogenase reductase Sdr
AX767_RS13890	COG1960	acyl-CoA dehydrogenase activity
AX767_RS13910	COG0683	leucine binding
AX767_RS13925	COG1024	Enoyl-CoA hydratase
AX767_RS13945	COG0489	protein tyrosine kinase activity
AX767_RS13965	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AX767_RS13970	COG1040	competence protein
AX767_RS13975	COG2226	methyltransferase
AX767_RS13990	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AX767_RS13995	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
AX767_RS14030	COG0109	protoheme IX farnesyltransferase activity
AX767_RS14035	COG1999	signal sequence binding
AX767_RS14040	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AX767_RS14055	COG0612	Peptidase, M16
AX767_RS14060	COG0612	Peptidase, M16
AX767_RS14065	COG0742	ribosomal rna small subunit methyltransferase
AX767_RS14070	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AX767_RS14075	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AX767_RS14080	COG1984	allophanate hydrolase subunit 2
AX767_RS14090	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
AX767_RS14100	COG2267	carboxylic ester hydrolase activity
AX767_RS14105	COG0588	phosphoglycerate mutase activity
AX767_RS14110	COG0583	DNA-binding transcription factor activity
AX767_RS14115	COG1028	Short-chain dehydrogenase reductase Sdr
AX767_RS14130	COG1959	2 iron, 2 sulfur cluster binding
AX767_RS14135	COG0747	negative chemotaxis
AX767_RS14140	COG4608	Belongs to the ABC transporter superfamily
AX767_RS14150	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AX767_RS14160	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AX767_RS14170	COG0193	aminoacyl-tRNA hydrolase activity
AX767_RS14175	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AX767_RS14180	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AX767_RS14190	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AX767_RS14205	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AX767_RS14210	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AX767_RS14220	COG1660	Displays ATPase and GTPase activities
AX767_RS14225	COG0497	DNA recombination
AX767_RS14230	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AX767_RS14235	COG1420	regulation of RNA biosynthetic process
AX767_RS14255	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AX767_RS14260	COG1758	RNA polymerase activity
AX767_RS14265	COG0194	GDP metabolic process
AX767_RS14270	COG1561	YicC-like family, N-terminal region
AX767_RS14275	COG0515	serine threonine protein kinase
AX767_RS14275	COG2815	serine threonine protein kinase
AX767_RS14290	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AX767_RS14295	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AX767_RS14340	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AX767_RS14345	COG0830	nickel cation binding
AX767_RS14350	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
AX767_RS14370	COG0804	urea catabolic process
AX767_RS14375	COG0832	Belongs to the urease beta subunit family
AX767_RS14385	COG0831	urea catabolic process
AX767_RS14390	COG5002	protein histidine kinase activity
AX767_RS14390	COG2198	Histidine kinase
AX767_RS14390	COG0784	Response regulator, receiver
AX767_RS14410	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AX767_RS14425	COG1136	(ABC) transporter
AX767_RS14435	COG1028	Short-chain dehydrogenase reductase Sdr
AX767_RS14440	COG2304	oxidoreductase activity
AX767_RS14450	COG0714	Associated with various cellular activities
AX767_RS14455	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AX767_RS14460	COG0084	hydrolase, TatD family'
AX767_RS14475	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AX767_RS14480	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AX767_RS14510	COG1028	Short-chain dehydrogenase reductase Sdr
AX767_RS14525	COG0583	DNA-binding transcription factor activity
AX767_RS14535	COG1283	sodium-dependent phosphate transmembrane transporter activity
AX767_RS14540	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AX767_RS14545	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AX767_RS14550	COG0196	riboflavin kinase activity
AX767_RS14570	COG1960	acyl-CoA dehydrogenase activity
AX767_RS14575	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AX767_RS14585	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AX767_RS14585	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AX767_RS14595	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AX767_RS14600	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AX767_RS14605	COG0492	ferredoxin-NADP+ reductase activity
AX767_RS14615	COG1674	ftsk spoiiie
AX767_RS14620	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AX767_RS14625	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AX767_RS14630	COG0559	Belongs to the binding-protein-dependent transport system permease family
AX767_RS14660	COG3181	Tripartite tricarboxylate transporter family receptor
AX767_RS14680	COG0411	ABC transporter
AX767_RS14715	COG2816	NAD+ diphosphatase activity
AX767_RS14720	COG0425	Belongs to the sulfur carrier protein TusA family
AX767_RS14730	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AX767_RS14735	COG0525	valine-tRNA ligase activity
AX767_RS14740	COG3022	response to hydroperoxide
AX767_RS14755	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AX767_RS14755	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AX767_RS14780	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AX767_RS14800	COG0477	Major facilitator Superfamily
AX767_RS14815	COG1304	FMN binding
AX767_RS14820	COG1289	transmembrane transporter activity
AX767_RS14825	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
AX767_RS14830	COG2807	transmembrane transport
AX767_RS14835	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AX767_RS14875	COG0165	Argininosuccinate lyase
AX767_RS14880	COG3275	phosphorelay sensor kinase activity
AX767_RS14910	COG3706	GGDEF domain
AX767_RS14915	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AX767_RS14925	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AX767_RS14930	COG0181	hydroxymethylbilane synthase activity
AX767_RS14950	COG1596	polysaccharide export
AX767_RS14960	COG3206	protein involved in exopolysaccharide biosynthesis
AX767_RS14960	COG0489	protein tyrosine kinase activity
AX767_RS14965	COG0297	glycogen (starch) synthase activity
AX767_RS14995	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AX767_RS15010	COG1530	ribonuclease E activity
AX767_RS15030	COG0616	signal peptide processing
AX767_RS15035	COG2223	nitrite transmembrane transporter activity
AX767_RS15040	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AX767_RS15045	COG0424	maF-like protein
AX767_RS15050	COG1399	metal-binding, possibly nucleic acid-binding protein
AX767_RS15055	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AX767_RS15060	COG0416	fatty acid biosynthetic process
AX767_RS15065	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AX767_RS15075	COG1028	Short-chain dehydrogenase reductase Sdr
AX767_RS15080	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AX767_RS15085	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AX767_RS15110	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AX767_RS15115	COG0481	GTPase activity
AX767_RS15120	COG0681	Belongs to the peptidase S26 family
AX767_RS15130	COG0571	ribonuclease III activity
AX767_RS15135	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AX767_RS15140	COG1381	Involved in DNA repair and RecF pathway recombination
AX767_RS15145	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AX767_RS15150	COG0736	holo-[acyl-carrier-protein] synthase activity
AX767_RS15165	COG1451	nucleotide metabolic process
AX767_RS15170	COG0443	Heat shock 70 kDa protein
AX767_RS15175	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AX767_RS15185	COG0762	integral membrane protein
AX767_RS15195	COG0159	tryptophan synthase activity
AX767_RS15200	COG0133	tryptophan synthase activity
AX767_RS15205	COG0135	phosphoribosylanthranilate isomerase activity
AX767_RS15210	COG0101	tRNA pseudouridine synthase activity
AX767_RS15220	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AX767_RS15225	COG0473	3-isopropylmalate dehydrogenase activity
AX767_RS15230	COG0066	3-isopropylmalate dehydratase activity
AX767_RS15235	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AX767_RS15255	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AX767_RS15260	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AX767_RS15265	COG1053	succinate dehydrogenase
AX767_RS15280	COG2188	Transcriptional regulator
AX767_RS15285	COG0039	L-malate dehydrogenase activity
AX767_RS15290	COG4106	trans-aconitate 2-methyltransferase activity
AX767_RS15305	COG1049	propionate catabolic process, 2-methylcitrate cycle
AX767_RS15370	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AX767_RS15380	COG3483	tryptophan 2,3-dioxygenase activity
AX767_RS15390	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
AX767_RS15420	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AX767_RS15425	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AX767_RS15435	COG0268	Binds directly to 16S ribosomal RNA
AX767_RS15440	COG0728	peptidoglycan biosynthetic process
AX767_RS15465	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AX767_RS15470	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AX767_RS15475	COG0617	tRNA 3'-terminal CCA addition
AX767_RS15485	COG1392	Phosphate transport regulator
AX767_RS15490	COG0306	phosphate transporter
AX767_RS15500	COG2205	protein histidine kinase activity
AX767_RS15520	COG0228	four-way junction DNA binding
AX767_RS15525	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AX767_RS15530	COG0336	Belongs to the RNA methyltransferase TrmD family
AX767_RS15535	COG0335	large ribosomal subunit rRNA binding
AX767_RS15540	COG0494	nUDIX hydrolase
AX767_RS15545	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
AX767_RS15550	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AX767_RS15555	COG1162	GTPase activity
AX767_RS15560	COG2154	pterin-4-alpha-carbinolamine dehydratase
AX767_RS15565	COG0501	Belongs to the peptidase M48B family
AX767_RS15570	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AX767_RS15575	COG0513	Belongs to the DEAD box helicase family
AX767_RS15600	COG0516	GMP reductase activity
AX767_RS15605	COG0210	DNA helicase
AX767_RS15615	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AX767_RS15630	COG0412	Dienelactone hydrolase
AX767_RS15645	COG3064	Membrane
AX767_RS15685	COG1722	exodeoxyribonuclease VII activity
AX767_RS15690	COG0142	geranyltranstransferase activity
AX767_RS15695	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AX767_RS15700	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AX767_RS15715	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AX767_RS15725	COG0477	Major facilitator Superfamily
AX767_RS15750	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AX767_RS15755	COG4149	molybdate abc transporter
AX767_RS15760	COG0725	ABC transporter, periplasmic molybdate-binding protein
AX767_RS15810	COG3608	succinylglutamate desuccinylase aspartoacylase
AX767_RS15810	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AX767_RS15820	COG2197	response regulator
AX767_RS15825	COG4585	Histidine kinase
AX767_RS15830	COG0129	dihydroxy-acid dehydratase activity
AX767_RS15835	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AX767_RS15840	COG2188	Transcriptional regulator
AX767_RS15845	COG3842	ATPase activity
AX767_RS15860	COG0395	ABC-type sugar transport system, permease component
AX767_RS15885	COG2351	hydroxyisourate hydrolase activity
AX767_RS15890	COG1320	monovalent cation:proton antiporter activity
AX767_RS15895	COG2212	antiporter activity
AX767_RS15905	COG0651	ATP synthesis coupled electron transport
AX767_RS15910	COG1006	Multisubunit Na H antiporter MnhC subunit
AX767_RS15915	COG2111	Na H antiporter
AX767_RS15915	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AX767_RS15920	COG1538	Outer membrane efflux protein
AX767_RS15935	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AX767_RS15970	COG0776	regulation of translation
AX767_RS15995	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AX767_RS16015	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AX767_RS16065	COG1546	Belongs to the CinA family
AX767_RS16065	COG1058	Belongs to the CinA family
AX767_RS16070	COG0174	glutamine synthetase
AX767_RS16080	COG3852	Histidine kinase
AX767_RS16095	COG0708	Exodeoxyribonuclease III
AX767_RS16185	COG2267	carboxylic ester hydrolase activity
AX767_RS16210	COG0668	transmembrane transport
AX767_RS16215	COG0366	Alpha amylase catalytic
AX767_RS16220	COG0366	Alpha amylase catalytic
AX767_RS16245	COG3265	gluconokinase activity
AX767_RS16250	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AX767_RS16255	COG0477	Major facilitator Superfamily
AX767_RS16270	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AX767_RS16275	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AX767_RS16280	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AX767_RS16290	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AX767_RS16300	COG2719	SpoVR family
AX767_RS16305	COG2718	Belongs to the UPF0229 family
AX767_RS16310	COG2766	serine protein kinase
AX767_RS16315	COG0484	heat shock protein binding
AX767_RS16320	COG0443	Heat shock 70 kDa protein
AX767_RS16325	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AX767_RS16340	COG0688	phosphatidylethanolamine metabolic process
AX767_RS16355	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AX767_RS16355	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AX767_RS16365	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AX767_RS16375	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AX767_RS16380	COG2186	Transcriptional regulator
AX767_RS16385	COG3181	Tripartite tricarboxylate transporter family receptor
AX767_RS16390	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AX767_RS16400	COG1012	belongs to the aldehyde dehydrogenase family
AX767_RS16415	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AX767_RS16420	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AX767_RS16485	COG0583	DNA-binding transcription factor activity
AX767_RS16490	COG0583	DNA-binding transcription factor activity
AX767_RS16495	COG0667	Aldo Keto reductase
AX767_RS16505	COG0515	serine threonine protein kinase
AX767_RS16505	COG2815	serine threonine protein kinase
AX767_RS16510	COG2116	formate transmembrane transporter activity
AX767_RS16520	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AX767_RS16535	COG0642	Histidine kinase
AX767_RS16555	COG1022	Amp-dependent synthetase and ligase
AX767_RS16570	COG4948	Mandelate Racemase Muconate Lactonizing
AX767_RS16615	COG0583	DNA-binding transcription factor activity
AX767_RS16630	COG5002	protein histidine kinase activity
AX767_RS16630	COG3447	MASE1 domain protein
AX767_RS16630	COG5001	Diguanylate cyclase
AX767_RS16660	COG0784	Response regulator, receiver
AX767_RS16660	COG2205	protein histidine kinase activity
AX767_RS16670	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AX767_RS16675	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AX767_RS16695	COG3186	Phenylalanine-4-hydroxylase
AX767_RS16700	COG2814	Major facilitator Superfamily
AX767_RS16710	COG0358	DNA primase activity
AX767_RS16715	COG1295	ribonuclease BN
AX767_RS16715	COG1959	2 iron, 2 sulfur cluster binding
AX767_RS16730	COG0824	Thioesterase
AX767_RS16740	COG3237	CsbD-like
AX767_RS16745	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AX767_RS16755	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AX767_RS16770	COG1611	Belongs to the LOG family
AX767_RS16775	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AX767_RS16785	COG0322	excinuclease ABC activity
AX767_RS16805	COG0596	Alpha beta hydrolase
AX767_RS16810	COG0473	3-isopropylmalate dehydrogenase activity
AX767_RS16825	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AX767_RS16845	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AX767_RS16850	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AX767_RS16860	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AX767_RS16865	COG0670	Belongs to the BI1 family
AX767_RS16870	COG3193	protein, possibly involved in utilization of glycolate and propanediol
AX767_RS16900	COG3128	pkhd-type hydroxylase
AX767_RS16905	COG4774	siderophore transport
AX767_RS16910	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AX767_RS16915	COG1477	protein flavinylation
AX767_RS16945	COG3634	alkyl hydroperoxide reductase activity
AX767_RS16950	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AX767_RS16965	COG0360	Binds together with S18 to 16S ribosomal RNA
AX767_RS16970	COG2965	DNA replication, synthesis of RNA primer
AX767_RS16975	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AX767_RS16980	COG0359	binds to the 23S rRNA
AX767_RS16985	COG0305	Participates in initiation and elongation during chromosome replication
AX767_RS16990	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AX767_RS16995	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AX767_RS17005	COG0436	Aminotransferase
AX767_RS17025	COG1763	Mo-molybdopterin cofactor biosynthetic process
AX767_RS17030	COG0303	'Molybdopterin
AX767_RS17035	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AX767_RS17040	COG0314	molybdopterin synthase activity
AX767_RS17045	COG3181	Tripartite tricarboxylate transporter family receptor
AX767_RS17050	COG0542	response to heat
AX767_RS17060	COG0183	Belongs to the thiolase family
AX767_RS17080	COG0659	secondary active sulfate transmembrane transporter activity
AX767_RS17105	COG2814	Major facilitator Superfamily
AX767_RS17120	COG3214	Protein conserved in bacteria
AX767_RS17140	COG0673	inositol 2-dehydrogenase activity
AX767_RS17160	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AX767_RS17165	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AX767_RS17170	COG1309	transcriptional regulator
AX767_RS17200	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AX767_RS17205	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AX767_RS17210	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AX767_RS17215	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AX767_RS17220	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AX767_RS17225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AX767_RS17225	COG0072	phenylalanine-tRNA ligase activity
AX767_RS17230	COG0776	regulation of translation
AX767_RS17245	COG0427	acetyl-CoA hydrolase
AX767_RS17265	COG2010	Cytochrome c
AX767_RS17275	COG4302	ethanolamine ammonia-lyase activity
AX767_RS17280	COG4303	Ethanolamine ammonia lyase large subunit
AX767_RS17285	COG0531	amino acid
AX767_RS17290	COG0545	Peptidyl-prolyl cis-trans isomerase
AX767_RS17300	COG2197	response regulator
AX767_RS17320	COG1472	Belongs to the glycosyl hydrolase 3 family
AX767_RS17340	COG1024	Enoyl-CoA hydratase
AX767_RS17355	COG1960	acyl-CoA dehydrogenase activity
AX767_RS17365	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AX767_RS17370	COG1024	Enoyl-CoA hydratase
AX767_RS17380	COG1024	Enoyl-CoA hydratase
AX767_RS17385	COG1802	Transcriptional regulator
AX767_RS17395	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AX767_RS17405	COG3181	Tripartite tricarboxylate transporter family receptor
AX767_RS17410	COG0318	PFAM AMP-dependent synthetase and ligase
AX767_RS17415	COG1960	acyl-CoA dehydrogenase activity
AX767_RS17425	COG1250	3-hydroxyacyl-CoA dehydrogenase
AX767_RS17425	COG1024	Enoyl-CoA hydratase
AX767_RS17445	COG0431	NADPH-dependent FMN reductase
AX767_RS17505	COG1960	acyl-CoA dehydrogenase activity
AX767_RS17510	COG1960	acyl-CoA dehydrogenase activity
AX767_RS17515	COG0318	PFAM AMP-dependent synthetase and ligase
AX767_RS17530	COG0583	DNA-binding transcription factor activity
AX767_RS17540	COG2818	Glycosylase
AX767_RS17545	COG0789	Transcriptional regulator
AX767_RS17565	COG0154	amidase activity
AX767_RS17570	COG1183	phosphatidylcholine synthase activity
AX767_RS17575	COG1160	GTP binding
AX767_RS17585	COG1132	(ABC) transporter
AX767_RS17590	COG3384	dioxygenase
AX767_RS17595	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AX767_RS17605	COG3038	cytochrome b561
AX767_RS17610	COG1028	Short-chain dehydrogenase reductase Sdr
AX767_RS17615	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AX767_RS17635	COG0142	geranyltranstransferase activity
AX767_RS17645	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AX767_RS17665	COG0587	DNA-directed DNA polymerase activity
AX767_RS17680	COG0583	DNA-binding transcription factor activity
AX767_RS17685	COG2031	fatty acid transporter
AX767_RS17695	COG2423	ornithine cyclodeaminase activity
AX767_RS17755	COG0071	Belongs to the small heat shock protein (HSP20) family
AX767_RS17780	COG4177	L-phenylalanine transmembrane transporter activity
AX767_RS17785	COG0559	Belongs to the binding-protein-dependent transport system permease family
AX767_RS17805	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AX767_RS17810	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AX767_RS17825	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AX767_RS17830	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AX767_RS17845	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AX767_RS17865	COG1253	flavin adenine dinucleotide binding
AX767_RS17870	COG3468	outer membrane autotransporter barrel domain protein
AX767_RS17875	COG0628	permease
AX767_RS17885	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AX767_RS17890	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AX767_RS17895	COG1233	COG1233 Phytoene dehydrogenase and related
AX767_RS17905	COG1741	Belongs to the pirin family
AX767_RS17920	COG1741	Belongs to the pirin family
AX767_RS17925	COG3148	PFAM DTW domain containing protein
AX767_RS17980	COG1054	Belongs to the UPF0176 family
AX767_RS18000	COG0848	biopolymer transport protein
AX767_RS18010	COG0824	Thioesterase
AX767_RS18015	COG0436	Aminotransferase
AX767_RS18020	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AX767_RS18025	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AX767_RS18040	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AX767_RS18040	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AX767_RS18080	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AX767_RS18085	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AX767_RS18090	COG0741	lytic transglycosylase activity
AX767_RS18110	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AX767_RS18130	COG0215	cysteine-tRNA ligase activity
AX767_RS18140	COG0825	malonyl-CoA metabolic process
AX767_RS18145	COG0037	tRNA processing
AX767_RS18150	COG0527	aspartate kinase activity
AX767_RS18180	COG2814	Major facilitator Superfamily
AX767_RS18195	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AX767_RS18200	COG2951	lytic endotransglycosylase activity
AX767_RS18205	COG2814	Major facilitator Superfamily
AX767_RS18215	COG2814	Major facilitator Superfamily
AX767_RS18235	COG0642	Histidine kinase
AX767_RS18290	COG1620	l-lactate permease
AX767_RS18345	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AX767_RS18350	COG1011	Hydrolase
AX767_RS18360	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
AX767_RS18365	COG1562	ergosterol biosynthetic process
AX767_RS18375	COG3158	transport of potassium into the cell
AX767_RS18380	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AX767_RS18385	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AX767_RS18395	COG0544	peptidyl-prolyl cis-trans isomerase activity
AX767_RS18400	COG0740	serine-type endopeptidase activity
AX767_RS18405	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AX767_RS18410	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AX767_RS18455	COG0114	fumarate hydratase activity
AX767_RS18465	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AX767_RS18475	COG4654	Cytochrome c, class I
AX767_RS18485	COG0129	dihydroxy-acid dehydratase activity
AX767_RS18490	COG0583	DNA-binding transcription factor activity
AX767_RS18495	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AX767_RS18500	COG1802	Transcriptional regulator
AX767_RS18520	COG0318	PFAM AMP-dependent synthetase and ligase
AX767_RS18535	COG0589	response to stress
AX767_RS18540	COG0730	response to heat
AX767_RS18560	COG1797	cobyrinic acid a,c-diamide synthase activity
AX767_RS18570	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AX767_RS18575	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AX767_RS18580	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AX767_RS18585	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
AX767_RS18605	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
AX767_RS18625	COG0657	acetylesterase activity
AX767_RS18630	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AX767_RS18640	COG1538	Outer membrane efflux protein
AX767_RS18650	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AX767_RS18655	COG0671	phosphoesterase, PA-phosphatase related
AX767_RS18660	COG1492	cobalamin metabolic process
AX767_RS18665	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AX767_RS18670	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AX767_RS18680	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AX767_RS18685	COG3550	peptidyl-serine autophosphorylation
AX767_RS18695	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AX767_RS18710	COG0783	Belongs to the Dps family
AX767_RS18720	COG0560	Phosphoserine phosphatase
AX767_RS18725	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AX767_RS18730	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AX767_RS18730	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AX767_RS18735	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AX767_RS18735	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AX767_RS18765	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AX767_RS18775	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
AX767_RS18780	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AX767_RS18790	COG0557	exoribonuclease II activity
AX767_RS18800	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AX767_RS18800	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AX767_RS18815	COG0052	Belongs to the universal ribosomal protein uS2 family
AX767_RS18820	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AX767_RS18825	COG0528	UMP kinase activity
AX767_RS18830	COG0233	cytoplasmic translational termination
AX767_RS18835	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AX767_RS18845	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AX767_RS18850	COG0750	zinc metalloprotease
AX767_RS18855	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AX767_RS18860	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
AX767_RS18865	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AX767_RS18870	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AX767_RS18875	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AX767_RS18880	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AX767_RS18885	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AX767_RS18890	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AX767_RS18895	COG0505	Belongs to the CarA family
AX767_RS18900	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AX767_RS18910	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AX767_RS18925	COG1534	Rna-binding protein
AX767_RS18930	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AX767_RS18935	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AX767_RS18945	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AX767_RS18975	COG1024	Enoyl-CoA hydratase
AX767_RS18980	COG1250	3-hydroxyacyl-CoA dehydrogenase
AX767_RS18990	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AX767_RS19000	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AX767_RS19005	COG0252	asparaginase activity
AX767_RS19020	COG0563	adenylate kinase activity
AX767_RS19025	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AX767_RS19030	COG2835	tetraacyldisaccharide 4'-kinase activity
AX767_RS19035	COG1663	tetraacyldisaccharide 4'-kinase activity
AX767_RS19040	COG0848	biopolymer transport protein
AX767_RS19045	COG0811	peptide transport
AX767_RS19050	COG1570	exodeoxyribonuclease VII activity
AX767_RS19055	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AX767_RS19080	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AX767_RS19085	COG0542	response to heat
AX767_RS19095	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AX767_RS19100	COG2925	Exonuclease
AX767_RS19110	COG2205	protein histidine kinase activity
AX767_RS19120	COG0318	PFAM AMP-dependent synthetase and ligase
AX767_RS19125	COG0402	S-adenosylhomocysteine deaminase activity
AX767_RS19135	COG1079	Belongs to the binding-protein-dependent transport system permease family
AX767_RS19140	COG4603	Belongs to the binding-protein-dependent transport system permease family
AX767_RS19145	COG3845	ABC transporter
AX767_RS19150	COG1744	ABC transporter substrate-binding protein PnrA-like
AX767_RS19155	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AX767_RS19170	COG1595	DNA-templated transcription, initiation
AX767_RS19190	COG0433	COG0433 Predicted ATPase
AX767_RS19205	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AX767_RS19245	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AX767_RS19275	COG0217	transcriptional regulatory protein
AX767_RS19280	COG0151	Belongs to the GarS family
AX767_RS19285	COG0408	coproporphyrinogen oxidase activity
AX767_RS19290	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AX767_RS19295	COG0799	negative regulation of ribosome biogenesis
AX767_RS19300	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AX767_RS19305	COG0424	maF-like protein
AX767_RS19310	COG1530	ribonuclease E activity
AX767_RS19315	COG1132	(ABC) transporter
AX767_RS19320	COG0823	Involved in the tonB-independent uptake of proteins
AX767_RS19335	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AX767_RS19365	COG0488	(ABC) transporter
AX767_RS19370	COG2890	protein-(glutamine-N5) methyltransferase activity
AX767_RS19375	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AX767_RS19385	COG2171	N-acyltransferase activity
AX767_RS19390	COG0436	Aminotransferase
AX767_RS19395	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AX767_RS19395	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AX767_RS19400	COG1643	Atp-dependent helicase
AX767_RS19405	COG0436	Aminotransferase
AX767_RS19410	COG0583	DNA-binding transcription factor activity
AX767_RS19420	COG0795	lipopolysaccharide-transporting ATPase activity
AX767_RS19430	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AX767_RS19470	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AX767_RS19475	COG1793	dna ligase
AX767_RS19485	COG4166	transmembrane transport
AX767_RS19490	COG4174	ABC transporter (Permease)
AX767_RS19495	COG4239	(ABC) transporter, permease
AX767_RS19500	COG4172	Belongs to the ABC transporter superfamily
AX767_RS19505	COG0477	Major facilitator Superfamily
AX767_RS19510	COG0779	Required for maturation of 30S ribosomal subunits
AX767_RS19515	COG0195	Participates in both transcription termination and antitermination
AX767_RS19515	COG2251	uridine kinase activity
AX767_RS19520	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AX767_RS19525	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AX767_RS19530	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AX767_RS19535	COG1217	gtp-binding protein TYPA
AX767_RS19555	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AX767_RS19560	COG2867	negative regulation of translational initiation
AX767_RS19580	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AX767_RS19580	COG0519	Catalyzes the synthesis of GMP from XMP
AX767_RS19595	COG4993	Dehydrogenase
AX767_RS19605	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AX767_RS19615	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AX767_RS19640	COG0668	transmembrane transport
AX767_RS19645	COG2358	TRAP transporter, solute receptor (TAXI family
AX767_RS19685	COG1595	DNA-templated transcription, initiation
AX767_RS19700	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AX767_RS19740	COG4135	transport system, permease component
AX767_RS19745	COG4136	ATPase activity
AX767_RS19765	COG4566	intracellular signal transduction
AX767_RS19780	COG2808	Putative FMN-binding domain
AX767_RS19795	COG1619	proteins homologs of microcin C7 resistance protein MccF
AX767_RS19830	COG0666	response to abiotic stimulus
AX767_RS19835	COG0084	hydrolase, TatD family'
AX767_RS19850	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AX767_RS19855	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AX767_RS19880	COG1742	UPF0060 membrane protein
AX767_RS19890	COG0747	negative chemotaxis
AX767_RS19895	COG0601	transmembrane transport
AX767_RS19900	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AX767_RS19905	COG0444	Belongs to the ABC transporter superfamily
AX767_RS19910	COG4608	Belongs to the ABC transporter superfamily
AX767_RS19920	COG1609	Transcriptional regulator
AX767_RS19930	COG0697	spore germination
AX767_RS19935	COG3181	Tripartite tricarboxylate transporter family receptor
AX767_RS19950	COG3550	peptidyl-serine autophosphorylation
AX767_RS19955	COG2183	response to ionizing radiation
AX767_RS19970	COG0534	Mate efflux family protein
AX767_RS19980	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AX767_RS19980	COG3008	intermembrane lipid transfer
AX767_RS19985	COG2995	paraquat-inducible protein a
AX767_RS19990	COG2995	paraquat-inducible protein a
AX767_RS19995	COG2814	Major facilitator Superfamily
AX767_RS20000	COG2814	Major facilitator Superfamily
AX767_RS20010	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AX767_RS20015	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
AX767_RS20025	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AX767_RS20035	COG0683	leucine binding
AX767_RS20040	COG0318	PFAM AMP-dependent synthetase and ligase
AX767_RS20055	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AX767_RS20060	COG0300	oxidoreductase activity
AX767_RS20070	COG1960	acyl-CoA dehydrogenase activity
AX767_RS20080	COG2130	NADP-dependent
AX767_RS20105	COG1960	acyl-CoA dehydrogenase activity
AX767_RS20110	COG0183	Belongs to the thiolase family
AX767_RS20115	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AX767_RS20120	COG1250	3-hydroxyacyl-CoA dehydrogenase
AX767_RS20120	COG1024	Enoyl-CoA hydratase
AX767_RS20130	COG0411	ABC transporter
AX767_RS20140	COG0559	Belongs to the binding-protein-dependent transport system permease family
AX767_RS20160	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AX767_RS20165	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AX767_RS20170	COG2917	probably involved in intracellular septation
AX767_RS20180	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AX767_RS20185	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AX767_RS20185	COG0047	phosphoribosylformylglycinamidine synthase activity
AX767_RS20190	COG0024	Methionine aminopeptidase
AX767_RS20210	COG2259	Doxx family
AX767_RS20215	COG0242	peptide deformylase activity
AX767_RS20220	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AX767_RS20235	COG1196	nuclear chromosome segregation
AX767_RS20265	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AX767_RS20270	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AX767_RS20275	COG4208	sulfate ABC transporter
AX767_RS20285	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AX767_RS20295	COG0450	alkyl hydroperoxide reductase
AX767_RS20305	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AX767_RS20315	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AX767_RS20325	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AX767_RS20325	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AX767_RS20330	COG1045	serine acetyltransferase
AX767_RS20350	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
AX767_RS20355	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AX767_RS20355	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AX767_RS20380	COG5002	protein histidine kinase activity
AX767_RS20385	COG0745	RESPONSE REGULATOR receiver
AX767_RS20390	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
AX767_RS20395	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AX767_RS20410	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AX767_RS20440	COG2895	sulfate adenylyltransferase (ATP) activity
AX767_RS20445	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AX767_RS20450	COG0492	ferredoxin-NADP+ reductase activity
AX767_RS20520	COG2985	domain, Protein
AX767_RS20525	COG0076	glutamate decarboxylase activity
AX767_RS20535	COG3181	Tripartite tricarboxylate transporter family receptor
AX767_RS20570	COG3829	transcription factor binding
AX767_RS20575	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AX767_RS20580	COG0642	Histidine kinase
AX767_RS20590	COG1414	Transcriptional regulator
AX767_RS20605	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AX767_RS20610	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AX767_RS20615	COG1414	Transcriptional regulator
AX767_RS20625	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AX767_RS20630	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AX767_RS20635	COG1183	phosphatidylcholine synthase activity
AX767_RS20640	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AX767_RS20645	COG0440	acetolactate synthase activity
AX767_RS20650	COG0028	Belongs to the TPP enzyme family
AX767_RS20675	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AX767_RS20685	COG0347	Belongs to the P(II) protein family
AX767_RS20710	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AX767_RS20715	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AX767_RS20725	COG1511	domain protein
AX767_RS20740	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AX767_RS20755	COG1024	Enoyl-CoA hydratase
AX767_RS20780	COG1012	belongs to the aldehyde dehydrogenase family