locus-tag	class	description
G3W90_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
G3W90_RS00010	COG0592	DNA-directed DNA polymerase activity
G3W90_RS00035	COG1408	metallophosphoesterase
G3W90_RS00050	COG0392	lysyltransferase activity
G3W90_RS00055	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G3W90_RS00060	COG3568	Endonuclease Exonuclease Phosphatase
G3W90_RS00075	COG4948	Mandelate Racemase Muconate Lactonizing
G3W90_RS00085	COG4149	molybdate abc transporter
G3W90_RS00090	COG3842	ATPase activity
G3W90_RS00105	COG2186	Transcriptional regulator
G3W90_RS00115	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G3W90_RS00140	COG2205	protein histidine kinase activity
G3W90_RS00145	COG0745	RESPONSE REGULATOR receiver
G3W90_RS00155	COG2608	mercury ion transmembrane transporter activity
G3W90_RS00165	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G3W90_RS00170	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G3W90_RS00190	COG0745	RESPONSE REGULATOR receiver
G3W90_RS00195	COG0642	Histidine kinase
G3W90_RS00200	COG1902	pentaerythritol trinitrate reductase activity
G3W90_RS00215	COG5487	UPF0391 membrane protein
G3W90_RS00220	COG0445	tRNA wobble uridine modification
G3W90_RS00225	COG0357	Ribosomal RNA small subunit methyltransferase G
G3W90_RS00230	COG1280	lysine exporter protein (LysE YggA)
G3W90_RS00255	COG0277	FAD linked oxidase domain protein
G3W90_RS00260	COG2096	Adenosyltransferase
G3W90_RS00285	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
G3W90_RS00295	COG0850	regulation of cytokinetic process
G3W90_RS00305	COG2233	PERMEase
G3W90_RS00310	COG2050	protein possibly involved in aromatic compounds catabolism
G3W90_RS00330	COG0559	Belongs to the binding-protein-dependent transport system permease family
G3W90_RS00365	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
G3W90_RS00390	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G3W90_RS00395	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G3W90_RS00405	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G3W90_RS00410	COG0583	DNA-binding transcription factor activity
G3W90_RS00415	COG0235	Class ii aldolase
G3W90_RS00425	COG1024	Enoyl-CoA hydratase
G3W90_RS00455	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G3W90_RS00510	COG0740	serine-type endopeptidase activity
G3W90_RS00520	COG1028	Short-chain dehydrogenase reductase Sdr
G3W90_RS00545	COG0477	Major facilitator Superfamily
G3W90_RS00550	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
G3W90_RS00555	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
G3W90_RS00560	COG1845	cytochrome c oxidase, subunit III
G3W90_RS00565	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
G3W90_RS00580	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
G3W90_RS00595	COG0004	ammonium transporteR
G3W90_RS00605	COG2207	Transcriptional regulator
G3W90_RS00610	COG2223	nitrite transmembrane transporter activity
G3W90_RS00620	COG2205	protein histidine kinase activity
G3W90_RS00625	COG4789	Type iii secretion
G3W90_RS00655	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G3W90_RS00660	COG0450	alkyl hydroperoxide reductase
G3W90_RS00665	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G3W90_RS00690	COG0640	Transcriptional regulator
G3W90_RS00710	COG0583	DNA-binding transcription factor activity
G3W90_RS00715	COG1960	acyl-CoA dehydrogenase activity
G3W90_RS00720	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W90_RS00760	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G3W90_RS00765	COG0700	Nucleoside recognition
G3W90_RS00795	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
G3W90_RS00800	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
G3W90_RS00805	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G3W90_RS00845	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
G3W90_RS00870	COG1228	amidohydrolase
G3W90_RS00910	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
G3W90_RS00915	COG0725	ABC transporter, periplasmic molybdate-binding protein
G3W90_RS00920	COG4149	molybdate abc transporter
G3W90_RS00950	COG0583	DNA-binding transcription factor activity
G3W90_RS00970	COG0646	methionine synthase
G3W90_RS00970	COG1410	methionine synthase
G3W90_RS00995	COG1309	transcriptional regulator
G3W90_RS01045	COG1335	isochorismatase
G3W90_RS01050	COG2080	2 iron, 2 sulfur cluster binding
G3W90_RS01065	COG2721	sulfolactate sulfo-lyase activity
G3W90_RS01085	COG4948	Mandelate Racemase Muconate Lactonizing
G3W90_RS01090	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G3W90_RS01100	COG1012	belongs to the aldehyde dehydrogenase family
G3W90_RS01110	COG1126	abc transporter atp-binding protein
G3W90_RS01115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G3W90_RS01125	COG0765	amino acid transport
G3W90_RS01145	COG0606	chelatase, subunit chli
G3W90_RS01155	COG0347	Belongs to the P(II) protein family
G3W90_RS01160	COG0004	ammonium transporteR
G3W90_RS01170	COG0277	FAD linked oxidase domain protein
G3W90_RS01175	COG0247	lactate metabolic process
G3W90_RS01185	COG0386	Belongs to the glutathione peroxidase family
G3W90_RS01200	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
G3W90_RS01205	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
G3W90_RS01215	COG0129	dihydroxy-acid dehydratase activity
G3W90_RS01225	COG3971	2-oxopent-4-enoate hydratase activity
G3W90_RS01250	COG1012	belongs to the aldehyde dehydrogenase family
G3W90_RS01265	COG1846	Transcriptional regulator
G3W90_RS01290	COG2974	May be involved in recombination
G3W90_RS01320	COG0745	RESPONSE REGULATOR receiver
G3W90_RS01325	COG0579	oxidoreductase
G3W90_RS01385	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G3W90_RS01390	COG1335	isochorismatase
G3W90_RS01400	COG1335	isochorismatase
G3W90_RS01430	COG0583	DNA-binding transcription factor activity
G3W90_RS01445	COG2072	flavoprotein involved in K transport
G3W90_RS01450	COG0708	Exodeoxyribonuclease III
G3W90_RS01455	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
G3W90_RS01465	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
G3W90_RS01470	COG0154	amidase activity
G3W90_RS01475	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
G3W90_RS01480	COG1077	Cell shape determining protein MreB Mrl
G3W90_RS01495	COG0768	penicillin binding
G3W90_RS01505	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G3W90_RS01525	COG0622	Phosphoesterase
G3W90_RS01530	COG2095	MarC family integral membrane protein
G3W90_RS01535	COG1028	Short-chain dehydrogenase reductase Sdr
G3W90_RS01545	COG0412	Dienelactone hydrolase
G3W90_RS01550	COG0583	DNA-binding transcription factor activity
G3W90_RS01565	COG0598	Magnesium transport protein CorA
G3W90_RS01585	COG3411	Ferredoxin
G3W90_RS01590	COG2945	thiolester hydrolase activity
G3W90_RS01595	COG1686	Belongs to the peptidase S11 family
G3W90_RS01600	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
G3W90_RS01605	COG0049	tRNA binding
G3W90_RS01610	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
G3W90_RS01615	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
G3W90_RS01620	COG0051	transcription antitermination factor activity, RNA binding
G3W90_RS01625	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
G3W90_RS01630	COG0088	Forms part of the polypeptide exit tunnel
G3W90_RS01635	COG0089	rRNA binding
G3W90_RS01640	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
G3W90_RS01645	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
G3W90_RS01650	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
G3W90_RS01655	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
G3W90_RS01660	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
G3W90_RS01665	COG0255	Belongs to the universal ribosomal protein uL29 family
G3W90_RS01670	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
G3W90_RS01675	COG0678	peroxiredoxin activity
G3W90_RS01695	COG3909	cytochrome
G3W90_RS01700	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G3W90_RS01715	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
G3W90_RS01720	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
G3W90_RS01730	COG0508	dehydrogenase complex catalyzes the overall conversion of
G3W90_RS01735	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G3W90_RS01740	COG0596	Alpha beta hydrolase
G3W90_RS01745	COG0281	malic enzyme
G3W90_RS01745	COG0280	phosphate acetyltransferase
G3W90_RS01750	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
G3W90_RS01755	COG1301	dicarboxylic acid transport
G3W90_RS01760	COG1252	NADH dehydrogenase
G3W90_RS01765	COG3243	poly(R)-hydroxyalkanoic acid synthase
G3W90_RS01770	COG0183	Belongs to the thiolase family
G3W90_RS01775	COG1028	Short-chain dehydrogenase reductase Sdr
G3W90_RS01780	COG1271	oxidase subunit
G3W90_RS01785	COG1294	oxidase, subunit
G3W90_RS01810	COG2205	protein histidine kinase activity
G3W90_RS01815	COG2130	NADP-dependent
G3W90_RS01825	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
G3W90_RS01830	COG0318	PFAM AMP-dependent synthetase and ligase
G3W90_RS01840	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
G3W90_RS01845	COG0321	lipoyl(octanoyl) transferase activity
G3W90_RS01850	COG2921	Belongs to the UPF0250 family
G3W90_RS01855	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
G3W90_RS01865	COG0356	it plays a direct role in the translocation of protons across the membrane
G3W90_RS01875	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
G3W90_RS01880	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
G3W90_RS01885	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
G3W90_RS01890	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
G3W90_RS01895	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
G3W90_RS01900	COG0355	proton-transporting ATP synthase activity, rotational mechanism
G3W90_RS01930	COG1129	ABC transporter
G3W90_RS01935	COG1172	Belongs to the binding-protein-dependent transport system permease family
G3W90_RS01940	COG1879	ABC-type sugar transport system periplasmic component
G3W90_RS01945	COG0673	inositol 2-dehydrogenase activity
G3W90_RS01950	COG0516	GMP reductase activity
G3W90_RS01950	COG0517	IMP dehydrogenase activity
G3W90_RS01960	COG1881	PFAM PEBP family protein
G3W90_RS01965	COG3588	fructose-bisphosphate aldolase
G3W90_RS01970	COG2902	Dehydrogenase
G3W90_RS02030	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G3W90_RS02035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G3W90_RS02085	COG1028	Short-chain dehydrogenase reductase Sdr
G3W90_RS02090	COG1028	Short-chain dehydrogenase reductase Sdr
G3W90_RS02100	COG3842	ATPase activity
G3W90_RS02105	COG0395	ABC-type sugar transport system, permease component
G3W90_RS02120	COG1233	COG1233 Phytoene dehydrogenase and related
G3W90_RS02125	COG1609	Transcriptional regulator
G3W90_RS02150	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
G3W90_RS02155	COG0792	nuclease activity
G3W90_RS02160	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
G3W90_RS02165	COG2823	Periplasmic or secreted lipoprotein
G3W90_RS02170	COG2084	Dehydrogenase
G3W90_RS02190	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
G3W90_RS02235	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
G3W90_RS02235	COG2124	cytochrome p450
G3W90_RS02240	COG1309	transcriptional regulator
G3W90_RS02245	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
G3W90_RS02270	COG2376	Dihydroxyacetone kinase
G3W90_RS02290	COG1175	transmembrane transport
G3W90_RS02295	COG0395	ABC-type sugar transport system, permease component
G3W90_RS02300	COG3842	ATPase activity
G3W90_RS02305	COG0445	tRNA wobble uridine modification
G3W90_RS02310	COG1346	cytolysis
G3W90_RS02315	COG1380	Effector of murein hydrolase LrgA
G3W90_RS02320	COG0277	FAD linked oxidase domain protein
G3W90_RS02410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G3W90_RS02460	COG0343	queuine tRNA-ribosyltransferase activity
G3W90_RS02465	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
G3W90_RS02470	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
G3W90_RS02490	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W90_RS02500	COG1960	acyl-CoA dehydrogenase activity
G3W90_RS02505	COG1024	Enoyl-CoA hydratase
G3W90_RS02520	COG0596	Alpha beta hydrolase
G3W90_RS02525	COG0583	DNA-binding transcription factor activity
G3W90_RS02535	COG0783	Belongs to the Dps family
G3W90_RS02540	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
G3W90_RS02555	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
G3W90_RS02560	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
G3W90_RS02565	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
G3W90_RS02570	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
G3W90_RS02575	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
G3W90_RS02580	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
G3W90_RS02585	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
G3W90_RS02590	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
G3W90_RS02595	COG1841	ribosomal large subunit assembly
G3W90_RS02600	COG0200	Binds to the 23S rRNA
G3W90_RS02605	COG0201	protein transport
G3W90_RS02615	COG0257	Belongs to the bacterial ribosomal protein bL36 family
G3W90_RS02620	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
G3W90_RS02625	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
G3W90_RS02630	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
G3W90_RS02635	COG0202	RNA polymerase activity
G3W90_RS02640	COG0203	ribosomal protein L17
G3W90_RS02650	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
G3W90_RS02650	COG0506	proline dehydrogenase activity
G3W90_RS02650	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
G3W90_RS02670	COG1960	acyl-CoA dehydrogenase activity
G3W90_RS02675	COG1024	Enoyl-CoA hydratase
G3W90_RS02690	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G3W90_RS02710	COG1028	Short-chain dehydrogenase reductase Sdr
G3W90_RS02720	COG0022	dehydrogenase e1 component
G3W90_RS02725	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
G3W90_RS02740	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
G3W90_RS02745	COG2814	Major facilitator Superfamily
G3W90_RS02760	COG2814	Major facilitator Superfamily
G3W90_RS02770	COG1686	Belongs to the peptidase S11 family
G3W90_RS02800	COG1595	DNA-templated transcription, initiation
G3W90_RS02825	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W90_RS02840	COG0667	Aldo Keto reductase
G3W90_RS02845	COG0346	lactoylglutathione lyase activity
G3W90_RS02890	COG4213	ABC transporter substrate-binding protein
G3W90_RS02895	COG4214	carbohydrate transport
G3W90_RS02900	COG1129	ABC transporter
G3W90_RS02940	COG0477	Major facilitator Superfamily
G3W90_RS02980	COG1022	Amp-dependent synthetase and ligase
G3W90_RS02985	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G3W90_RS02995	COG1028	Short-chain dehydrogenase reductase Sdr
G3W90_RS03015	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
G3W90_RS03020	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
G3W90_RS03025	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
G3W90_RS03030	COG2205	protein histidine kinase activity
G3W90_RS03035	COG0745	RESPONSE REGULATOR receiver
G3W90_RS03040	COG1187	pseudouridine synthase activity
G3W90_RS03050	COG0745	RESPONSE REGULATOR receiver
G3W90_RS03055	COG0642	Histidine kinase
G3W90_RS03065	COG0326	Molecular chaperone. Has ATPase activity
G3W90_RS03070	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W90_RS03075	COG3181	Tripartite tricarboxylate transporter family receptor
G3W90_RS03080	COG1960	acyl-CoA dehydrogenase activity
G3W90_RS03085	COG0583	DNA-binding transcription factor activity
G3W90_RS03095	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
G3W90_RS03105	COG1012	belongs to the aldehyde dehydrogenase family
G3W90_RS03115	COG0318	PFAM AMP-dependent synthetase and ligase
G3W90_RS03120	COG2267	carboxylic ester hydrolase activity
G3W90_RS03135	COG0183	Belongs to the thiolase family
G3W90_RS03155	COG1764	response to oxidative stress
G3W90_RS03160	COG1846	Transcriptional regulator
G3W90_RS03170	COG1250	3-hydroxyacyl-CoA dehydrogenase
G3W90_RS03175	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
G3W90_RS03195	COG0724	RNA recognition motif
G3W90_RS03200	COG3530	Putative quorum-sensing-regulated virulence factor
G3W90_RS03205	COG0513	Belongs to the DEAD box helicase family
G3W90_RS03215	COG0842	Transport permease protein
G3W90_RS03220	COG1131	(ABC) transporter
G3W90_RS03225	COG0583	DNA-binding transcription factor activity
G3W90_RS03230	COG0625	glutathione transferase activity
G3W90_RS03240	COG2124	cytochrome p450
G3W90_RS03245	COG0640	Transcriptional regulator
G3W90_RS03250	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
G3W90_RS03270	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
G3W90_RS03275	COG4208	sulfate ABC transporter
G3W90_RS03285	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
G3W90_RS03310	COG1652	LysM domain
G3W90_RS03315	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
G3W90_RS03320	COG2733	membrane
G3W90_RS03325	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G3W90_RS03330	COG1473	amidohydrolase
G3W90_RS03345	COG0243	molybdopterin cofactor binding
G3W90_RS03360	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W90_RS03425	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
G3W90_RS03430	COG4106	trans-aconitate 2-methyltransferase activity
G3W90_RS03445	COG2076	Multidrug Resistance protein
G3W90_RS03455	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
G3W90_RS03460	COG1086	Polysaccharide biosynthesis protein
G3W90_RS03525	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
G3W90_RS03540	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
G3W90_RS03555	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G3W90_RS03575	COG0662	Cupin 2, conserved barrel domain protein
G3W90_RS03575	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
G3W90_RS03580	COG1216	Glycosyl transferase, family 2
G3W90_RS03580	COG0438	transferase activity, transferring glycosyl groups
G3W90_RS03595	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
G3W90_RS03595	COG2755	lipolytic protein G-D-S-L family
G3W90_RS03605	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
G3W90_RS03610	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
G3W90_RS03620	COG0753	catalase activity
G3W90_RS03635	COG2119	membrane
G3W90_RS03650	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
G3W90_RS03665	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
G3W90_RS03670	COG1309	transcriptional regulator
G3W90_RS03675	COG2309	aminopeptidase activity
G3W90_RS03715	COG1172	Belongs to the binding-protein-dependent transport system permease family
G3W90_RS03730	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G3W90_RS03790	COG3064	Membrane
G3W90_RS03810	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
G3W90_RS03815	COG2721	sulfolactate sulfo-lyase activity
G3W90_RS03820	COG2186	Transcriptional regulator
G3W90_RS03825	COG1028	Short-chain dehydrogenase reductase Sdr
G3W90_RS03835	COG0765	amino acid transport
G3W90_RS03840	COG0765	amino acid transport
G3W90_RS03855	COG4948	Mandelate Racemase Muconate Lactonizing
G3W90_RS03875	COG2188	Transcriptional regulator
G3W90_RS03910	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
G3W90_RS03915	COG0066	3-isopropylmalate dehydratase activity
G3W90_RS03945	COG0431	NADPH-dependent FMN reductase
G3W90_RS03945	COG3976	FMN-binding domain protein
G3W90_RS03945	COG1053	succinate dehydrogenase
G3W90_RS03965	COG1960	acyl-CoA dehydrogenase activity
G3W90_RS03975	COG1250	3-hydroxyacyl-CoA dehydrogenase
G3W90_RS03975	COG1024	Enoyl-CoA hydratase
G3W90_RS03980	COG2852	Protein conserved in bacteria
G3W90_RS03985	COG0183	Belongs to the thiolase family
G3W90_RS04005	COG1024	Enoyl-CoA hydratase
G3W90_RS04010	COG1607	acyl-coa hydrolase
G3W90_RS04015	COG5265	(ABC) transporter
G3W90_RS04020	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G3W90_RS04025	COG0583	DNA-binding transcription factor activity
G3W90_RS04035	COG0765	amino acid transport
G3W90_RS04040	COG0765	amino acid transport
G3W90_RS04045	COG1126	abc transporter atp-binding protein
G3W90_RS04050	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G3W90_RS04065	COG1280	lysine exporter protein (LysE YggA)
G3W90_RS04075	COG2003	Belongs to the UPF0758 family
G3W90_RS04085	COG0418	dihydroorotase activity
G3W90_RS04120	COG1414	Transcriptional regulator
G3W90_RS04125	COG0501	Belongs to the peptidase M48B family
G3W90_RS04130	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
G3W90_RS04165	COG1187	pseudouridine synthase activity
G3W90_RS04170	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G3W90_RS04180	COG1030	water channel activity
G3W90_RS04185	COG0330	HflC and HflK could
G3W90_RS04190	COG0598	Magnesium transport protein CorA
G3W90_RS04205	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G3W90_RS04215	COG2807	transmembrane transport
G3W90_RS04230	COG2175	clavaminate synthase activity
G3W90_RS04245	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G3W90_RS04260	COG2175	clavaminate synthase activity
G3W90_RS04305	COG0508	dehydrogenase complex catalyzes the overall conversion of
G3W90_RS04305	COG0596	Alpha beta hydrolase
G3W90_RS04315	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G3W90_RS04325	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3W90_RS04335	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
G3W90_RS04350	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
G3W90_RS04355	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
G3W90_RS04360	COG0523	cobalamin synthesis protein
G3W90_RS04375	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
G3W90_RS04380	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
G3W90_RS04385	COG2001	Belongs to the MraZ family
G3W90_RS04390	COG0275	rRNA processing
G3W90_RS04405	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
G3W90_RS04410	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
G3W90_RS04415	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
G3W90_RS04420	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
G3W90_RS04425	COG0772	Belongs to the SEDS family
G3W90_RS04430	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
G3W90_RS04435	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
G3W90_RS04440	COG1181	Belongs to the D-alanine--D-alanine ligase family
G3W90_RS04445	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
G3W90_RS04455	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
G3W90_RS04460	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
G3W90_RS04475	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
G3W90_RS04480	COG0575	Belongs to the CDS family
G3W90_RS04490	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G3W90_RS04495	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
G3W90_RS04510	COG3150	esterase
G3W90_RS04515	COG2197	response regulator
G3W90_RS04525	COG0772	Belongs to the SEDS family
G3W90_RS04530	COG0312	modulator of DNA gyrase
G3W90_RS04535	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
G3W90_RS04545	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
G3W90_RS04560	COG0511	ligase activity, forming carbon-carbon bonds
G3W90_RS04565	COG0439	Biotin carboxylase
G3W90_RS04570	COG2264	protein methyltransferase activity
G3W90_RS04580	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G3W90_RS04590	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G3W90_RS04625	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
G3W90_RS04630	COG3416	Protein conserved in bacteria
G3W90_RS04630	COG2943	transferase activity, transferring hexosyl groups
G3W90_RS04640	COG2204	response regulator
G3W90_RS04650	COG2205	protein histidine kinase activity
G3W90_RS04655	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
G3W90_RS04665	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G3W90_RS04670	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G3W90_RS04705	COG0037	tRNA processing
G3W90_RS04715	COG1028	Short-chain dehydrogenase reductase Sdr
G3W90_RS04725	COG2175	clavaminate synthase activity
G3W90_RS04735	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
G3W90_RS04740	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3W90_RS04765	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
G3W90_RS04775	COG0617	tRNA 3'-terminal CCA addition
G3W90_RS04790	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
G3W90_RS04795	COG0583	DNA-binding transcription factor activity
G3W90_RS04805	COG2200	EAL domain
G3W90_RS04810	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G3W90_RS04825	COG0110	maltose O-acetyltransferase activity
G3W90_RS04830	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
G3W90_RS04835	COG1522	sequence-specific DNA binding
G3W90_RS04845	COG1254	Belongs to the acylphosphatase family
G3W90_RS04875	COG0318	PFAM AMP-dependent synthetase and ligase
G3W90_RS04880	COG0183	Belongs to the thiolase family
G3W90_RS04910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G3W90_RS04915	COG4597	amino acid ABC transporter
G3W90_RS04920	COG0765	amino acid transport
G3W90_RS04925	COG1126	abc transporter atp-binding protein
G3W90_RS04955	COG2072	flavoprotein involved in K transport
G3W90_RS04975	COG0129	dihydroxy-acid dehydratase activity
G3W90_RS04990	COG3386	PFAM SMP-30 Gluconolaconase
G3W90_RS05000	COG1012	belongs to the aldehyde dehydrogenase family
G3W90_RS05005	COG1879	ABC-type sugar transport system periplasmic component
G3W90_RS05020	COG4214	carbohydrate transport
G3W90_RS05025	COG1129	ABC transporter
G3W90_RS05030	COG1172	Belongs to the binding-protein-dependent transport system permease family
G3W90_RS05035	COG1172	Belongs to the binding-protein-dependent transport system permease family
G3W90_RS05065	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
G3W90_RS05065	COG0189	ligase activity
G3W90_RS05070	COG0189	ligase activity
G3W90_RS05070	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
G3W90_RS05075	COG1132	(ABC) transporter
G3W90_RS05085	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
G3W90_RS05090	COG4178	(ABC) transporter
G3W90_RS05100	COG1459	type II secretion system
G3W90_RS05145	COG4970	Tfp pilus assembly protein FimT
G3W90_RS05160	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
G3W90_RS05170	COG1765	OsmC-like protein
G3W90_RS05175	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
G3W90_RS05190	COG1473	amidohydrolase
G3W90_RS05195	COG4166	transmembrane transport
G3W90_RS05200	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G3W90_RS05205	COG0444	Belongs to the ABC transporter superfamily
G3W90_RS05210	COG4608	Belongs to the ABC transporter superfamily
G3W90_RS05215	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
G3W90_RS05220	COG1840	ABC-type Fe3 transport system, periplasmic component
G3W90_RS05230	COG3842	ATPase activity
G3W90_RS05245	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
G3W90_RS05250	COG0166	Belongs to the GPI family
G3W90_RS05255	COG0439	Biotin carboxylase
G3W90_RS05260	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W90_RS05275	COG1802	Transcriptional regulator
G3W90_RS05290	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G3W90_RS05305	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
G3W90_RS05310	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
G3W90_RS05315	COG0745	RESPONSE REGULATOR receiver
G3W90_RS05320	COG5002	protein histidine kinase activity
G3W90_RS05325	COG0459	protein refolding
G3W90_RS05330	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
G3W90_RS05335	COG2186	Transcriptional regulator
G3W90_RS05340	COG2807	transmembrane transport
G3W90_RS05345	COG0456	acetyltransferase
G3W90_RS05365	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G3W90_RS05370	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W90_RS05380	COG0318	PFAM AMP-dependent synthetase and ligase
G3W90_RS05405	COG2207	Transcriptional regulator
G3W90_RS05415	COG0625	glutathione transferase activity
G3W90_RS05435	COG4772	TonB-dependent receptor
G3W90_RS05445	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
G3W90_RS05455	COG1560	Kdo2-lipid A biosynthetic process
G3W90_RS05465	COG0218	Necessary for normal cell division and for the maintenance of normal septation
G3W90_RS05475	COG1333	cytochrome c biogenesis protein
G3W90_RS05480	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
G3W90_RS05485	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
G3W90_RS05490	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
G3W90_RS05505	COG1965	Belongs to the frataxin family
G3W90_RS05540	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
G3W90_RS05550	COG0232	Belongs to the dGTPase family. Type 2 subfamily
G3W90_RS05575	COG0069	glutamate synthase activity
G3W90_RS05575	COG0067	glutamate synthase
G3W90_RS05575	COG0070	glutamate synthase
G3W90_RS05585	COG1127	ABC transporter
G3W90_RS05590	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G3W90_RS05595	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G3W90_RS05615	COG1131	(ABC) transporter
G3W90_RS05620	COG0842	Transport permease protein
G3W90_RS05625	COG5007	Belongs to the BolA IbaG family
G3W90_RS05630	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
G3W90_RS05635	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
G3W90_RS05640	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
G3W90_RS05650	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
G3W90_RS05655	COG0131	Imidazoleglycerol-phosphate dehydratase
G3W90_RS05665	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
G3W90_RS05675	COG1301	dicarboxylic acid transport
G3W90_RS05685	COG0107	imidazoleglycerol-phosphate synthase activity
G3W90_RS05690	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
G3W90_RS05695	COG0140	phosphoribosyl-ATP diphosphatase activity
G3W90_RS05705	COG0537	adenosine 5'-monophosphoramidase activity
G3W90_RS05710	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G3W90_RS05715	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G3W90_RS05720	COG0805	protein transport
G3W90_RS05725	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G3W90_RS05730	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
G3W90_RS05735	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
G3W90_RS05740	COG1970	mechanosensitive ion channel activity
G3W90_RS05745	COG0723	plastoquinol--plastocyanin reductase activity
G3W90_RS05750	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
G3W90_RS05755	COG2857	Cytochrome c1
G3W90_RS05760	COG0625	glutathione transferase activity
G3W90_RS05765	COG2969	positive regulation of protein catabolic process
G3W90_RS05775	COG3181	Tripartite tricarboxylate transporter family receptor
G3W90_RS05785	COG1309	transcriptional regulator
G3W90_RS05800	COG0653	protein targeting
G3W90_RS05805	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
G3W90_RS05815	COG0494	nUDIX hydrolase
G3W90_RS05820	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
G3W90_RS05825	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
G3W90_RS05835	COG1696	Membrane protein involved in D-alanine export
G3W90_RS05865	COG0142	geranyltranstransferase activity
G3W90_RS05870	COG0261	This protein binds to 23S rRNA in the presence of protein L20
G3W90_RS05875	COG0211	Belongs to the bacterial ribosomal protein bL27 family
G3W90_RS05880	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
G3W90_RS05885	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
G3W90_RS05895	COG0494	nUDIX hydrolase
G3W90_RS05900	COG0442	prolyl-tRNA aminoacylation
G3W90_RS05905	COG0741	lytic transglycosylase activity
G3W90_RS05910	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
G3W90_RS05920	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
G3W90_RS05925	COG2890	protein-(glutamine-N5) methyltransferase activity
G3W90_RS05930	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
G3W90_RS05935	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
G3W90_RS05945	COG1511	domain protein
G3W90_RS05945	COG3264	Mechanosensitive ion channel
G3W90_RS05950	COG0584	glycerophosphoryl diester phosphodiesterase
G3W90_RS05955	COG3842	ATPase activity
G3W90_RS05960	COG0395	ABC-type sugar transport system, permease component
G3W90_RS05965	COG1175	transmembrane transport
G3W90_RS05975	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G3W90_RS05995	COG2226	methyltransferase
G3W90_RS06010	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
G3W90_RS06015	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
G3W90_RS06020	COG3842	ATPase activity
G3W90_RS06025	COG1176	ABC-type spermidine putrescine transport system, permease component I
G3W90_RS06030	COG1177	transmembrane transport
G3W90_RS06045	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
G3W90_RS06070	COG3568	Endonuclease Exonuclease Phosphatase
G3W90_RS06075	COG0302	gtp cyclohydrolase
G3W90_RS06085	COG2076	Multidrug Resistance protein
G3W90_RS06125	COG4585	Histidine kinase
G3W90_RS06130	COG2197	response regulator
G3W90_RS06140	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
G3W90_RS06145	COG0793	Belongs to the peptidase S41A family
G3W90_RS06150	COG0588	phosphoglycerate mutase activity
G3W90_RS06155	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G3W90_RS06165	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
G3W90_RS06170	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
G3W90_RS06180	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
G3W90_RS06190	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
G3W90_RS06195	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
G3W90_RS06200	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
G3W90_RS06205	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
G3W90_RS06230	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G3W90_RS06230	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G3W90_RS06235	COG3132	Protein of unknown function, DUF480
G3W90_RS06250	COG0489	protein tyrosine kinase activity
G3W90_RS06255	COG2223	nitrite transmembrane transporter activity
G3W90_RS06265	COG3383	formate dehydrogenase (NAD+) activity
G3W90_RS06290	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
G3W90_RS06295	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
G3W90_RS06300	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G3W90_RS06315	COG2003	Belongs to the UPF0758 family
G3W90_RS06320	COG1047	Peptidyl-prolyl cis-trans
G3W90_RS06325	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
G3W90_RS06330	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
G3W90_RS06340	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
G3W90_RS06375	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
G3W90_RS06380	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
G3W90_RS06455	COG3162	membrane
G3W90_RS06465	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G3W90_RS06465	COG1042	CoA-binding domain protein
G3W90_RS06465	COG0045	succinate-CoA ligase (ADP-forming) activity
G3W90_RS06470	COG0123	including yeast histone deacetylase and acetoin utilization protein
G3W90_RS06475	COG0589	response to stress
G3W90_RS06480	COG2217	Heavy metal translocating P-type atpase
G3W90_RS06490	COG3278	Belongs to the heme-copper respiratory oxidase family
G3W90_RS06525	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G3W90_RS06530	COG0635	Involved in the biosynthesis of porphyrin-containing compound
G3W90_RS06545	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G3W90_RS06555	COG0671	phosphoesterase, PA-phosphatase related
G3W90_RS06595	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
G3W90_RS06600	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
G3W90_RS06605	COG0784	Response regulator, receiver
G3W90_RS06605	COG4191	Histidine kinase
G3W90_RS06630	COG0071	Belongs to the small heat shock protein (HSP20) family
G3W90_RS06685	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G3W90_RS06690	COG0589	response to stress
G3W90_RS06695	COG0589	response to stress
G3W90_RS06710	COG0589	response to stress
G3W90_RS06730	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G3W90_RS06740	COG1914	H( )-stimulated, divalent metal cation uptake system
G3W90_RS06745	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
G3W90_RS06750	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
G3W90_RS06765	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3W90_RS06770	COG1396	sequence-specific DNA binding
G3W90_RS06780	COG0242	peptide deformylase activity
G3W90_RS06795	COG4638	Rieske (2fe-2S)
G3W90_RS06815	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G3W90_RS06835	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
G3W90_RS06880	COG0318	PFAM AMP-dependent synthetase and ligase
G3W90_RS06930	COG0438	transferase activity, transferring glycosyl groups
G3W90_RS06965	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
G3W90_RS06980	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G3W90_RS06985	COG2175	clavaminate synthase activity
G3W90_RS07010	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W90_RS07015	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G3W90_RS07015	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G3W90_RS07020	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G3W90_RS07020	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G3W90_RS07025	COG1024	Enoyl-CoA hydratase
G3W90_RS07045	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
G3W90_RS07060	COG1335	isochorismatase
G3W90_RS07065	COG1802	Transcriptional regulator
G3W90_RS07080	COG2271	Major facilitator Superfamily
G3W90_RS07100	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G3W90_RS07125	COG3128	pkhd-type hydroxylase
G3W90_RS07130	COG4774	siderophore transport
G3W90_RS07135	COG5002	protein histidine kinase activity
G3W90_RS07140	COG2197	response regulator
G3W90_RS07145	COG0180	Tryptophanyl-tRNA synthetase
G3W90_RS07150	COG1994	Peptidase M50
G3W90_RS07155	COG0009	L-threonylcarbamoyladenylate synthase
G3W90_RS07165	COG0613	PHP domain protein
G3W90_RS07175	COG0306	phosphate transporter
G3W90_RS07220	COG3540	Alkaline phosphatase
G3W90_RS07235	COG1595	DNA-templated transcription, initiation
G3W90_RS07240	COG0477	Major facilitator Superfamily
G3W90_RS07245	COG0829	nickel cation binding
G3W90_RS07285	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
G3W90_RS07355	COG0163	prenyltransferase activity
G3W90_RS07360	COG0523	cobalamin synthesis protein
G3W90_RS07365	COG1529	Aldehyde oxidase and xanthine dehydrogenase
G3W90_RS07365	COG2080	2 iron, 2 sulfur cluster binding
G3W90_RS07380	COG0583	DNA-binding transcription factor activity
G3W90_RS07385	COG2233	PERMEase
G3W90_RS07390	COG0280	phosphate acetyltransferase
G3W90_RS07390	COG0281	malic enzyme
G3W90_RS07395	COG2084	Dehydrogenase
G3W90_RS07400	COG3622	Belongs to the hyi family
G3W90_RS07405	COG3960	tartronate-semialdehyde synthase activity
G3W90_RS07410	COG0583	DNA-binding transcription factor activity
G3W90_RS07425	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G3W90_RS07430	COG3181	Tripartite tricarboxylate transporter family receptor
G3W90_RS07435	COG0251	oxidation-reduction process
G3W90_RS07445	COG0179	Fumarylacetoacetate (FAA) hydrolase
G3W90_RS07450	COG3971	2-oxopent-4-enoate hydratase activity
G3W90_RS07460	COG3548	integral membrane protein
G3W90_RS07500	COG0427	acetyl-CoA hydrolase
G3W90_RS07525	COG1012	belongs to the aldehyde dehydrogenase family
G3W90_RS07530	COG3386	PFAM SMP-30 Gluconolaconase
G3W90_RS07535	COG1024	Enoyl-CoA hydratase
G3W90_RS07540	COG1609	Transcriptional regulator
G3W90_RS07550	COG0318	PFAM AMP-dependent synthetase and ligase
G3W90_RS07555	COG1028	Short-chain dehydrogenase reductase Sdr
G3W90_RS07585	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G3W90_RS07590	COG0439	Biotin carboxylase
G3W90_RS07605	COG0559	Belongs to the binding-protein-dependent transport system permease family
G3W90_RS07625	COG0318	PFAM AMP-dependent synthetase and ligase
G3W90_RS07665	COG4221	oxidoreductase activity
G3W90_RS07710	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G3W90_RS07765	COG0628	permease
G3W90_RS07770	COG2186	Transcriptional regulator
G3W90_RS07775	COG1301	dicarboxylic acid transport
G3W90_RS07780	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
G3W90_RS07805	COG0656	L-ascorbic acid biosynthetic process
G3W90_RS07810	COG1953	Uracil, thiamine, allantoin
G3W90_RS07815	COG2233	PERMEase
G3W90_RS07830	COG1953	Uracil, thiamine, allantoin
G3W90_RS07850	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G3W90_RS07865	COG2186	Transcriptional regulator
G3W90_RS07970	COG1280	lysine exporter protein (LysE YggA)
G3W90_RS07975	COG2133	pyrroloquinoline quinone binding
G3W90_RS07985	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
G3W90_RS07990	COG1021	2,3-dihydroxybenzoate-AMP ligase
G3W90_RS08025	COG1320	monovalent cation:proton antiporter activity
G3W90_RS08030	COG2212	antiporter activity
G3W90_RS08040	COG0651	ATP synthesis coupled electron transport
G3W90_RS08045	COG1006	Multisubunit Na H antiporter MnhC subunit
G3W90_RS08050	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
G3W90_RS08050	COG2111	Na H antiporter
G3W90_RS08055	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
G3W90_RS08065	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
G3W90_RS08085	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
G3W90_RS08090	COG0287	Prephenate dehydrogenase
G3W90_RS08100	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
G3W90_RS08120	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G3W90_RS08150	COG4797	methyltransferase
G3W90_RS08150	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G3W90_RS08160	COG1187	pseudouridine synthase activity
G3W90_RS08185	COG1546	Belongs to the CinA family
G3W90_RS08185	COG1058	Belongs to the CinA family
G3W90_RS08190	COG0174	glutamine synthetase
G3W90_RS08200	COG3852	Histidine kinase
G3W90_RS08205	COG2204	response regulator
G3W90_RS08215	COG0708	Exodeoxyribonuclease III
G3W90_RS08220	COG1956	GAF domain-containing protein
G3W90_RS08255	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G3W90_RS08285	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
G3W90_RS08290	COG0277	FAD linked oxidase domain protein
G3W90_RS08300	COG1295	ribonuclease BN
G3W90_RS08305	COG3118	belongs to the thioredoxin family
G3W90_RS08350	COG1538	Outer membrane efflux protein
G3W90_RS08365	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G3W90_RS08370	COG3181	Tripartite tricarboxylate transporter family receptor
G3W90_RS08385	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
G3W90_RS08390	COG0596	Alpha beta hydrolase
G3W90_RS08400	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
G3W90_RS08405	COG2818	Glycosylase
G3W90_RS08410	COG2719	SpoVR family
G3W90_RS08415	COG2718	Belongs to the UPF0229 family
G3W90_RS08420	COG2766	serine protein kinase
G3W90_RS08430	COG0179	Fumarylacetoacetate (FAA) hydrolase
G3W90_RS08435	COG2186	Transcriptional regulator
G3W90_RS08460	COG0673	inositol 2-dehydrogenase activity
G3W90_RS08475	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G3W90_RS08520	COG0484	heat shock protein binding
G3W90_RS08525	COG0443	Heat shock 70 kDa protein
G3W90_RS08530	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
G3W90_RS08545	COG0688	phosphatidylethanolamine metabolic process
G3W90_RS08555	COG2721	sulfolactate sulfo-lyase activity
G3W90_RS08560	COG2706	6-phosphogluconolactonase activity
G3W90_RS08575	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G3W90_RS08580	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G3W90_RS08585	COG2186	Transcriptional regulator
G3W90_RS08595	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G3W90_RS08600	COG1012	belongs to the aldehyde dehydrogenase family
G3W90_RS08625	COG2188	Transcriptional regulator
G3W90_RS08630	COG0683	leucine binding
G3W90_RS08645	COG0559	Belongs to the binding-protein-dependent transport system permease family
G3W90_RS08680	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G3W90_RS08690	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
G3W90_RS08715	COG1137	ATPase activity
G3W90_RS08745	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
G3W90_RS08765	COG1125	glycine betaine transport
G3W90_RS08765	COG0517	IMP dehydrogenase activity
G3W90_RS08770	COG2814	Major facilitator Superfamily
G3W90_RS08780	COG0358	DNA primase activity
G3W90_RS08785	COG1295	ribonuclease BN
G3W90_RS08810	COG3237	CsbD-like
G3W90_RS08815	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
G3W90_RS08840	COG1611	Belongs to the LOG family
G3W90_RS08845	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
G3W90_RS08855	COG0322	excinuclease ABC activity
G3W90_RS08870	COG0473	3-isopropylmalate dehydrogenase activity
G3W90_RS08885	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G3W90_RS08905	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
G3W90_RS08910	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
G3W90_RS08925	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
G3W90_RS08930	COG0670	Belongs to the BI1 family
G3W90_RS08935	COG3193	protein, possibly involved in utilization of glycolate and propanediol
G3W90_RS08965	COG3128	pkhd-type hydroxylase
G3W90_RS08980	COG1477	protein flavinylation
G3W90_RS09010	COG3634	alkyl hydroperoxide reductase activity
G3W90_RS09025	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
G3W90_RS09040	COG0360	Binds together with S18 to 16S ribosomal RNA
G3W90_RS09045	COG2965	DNA replication, synthesis of RNA primer
G3W90_RS09050	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
G3W90_RS09055	COG0359	binds to the 23S rRNA
G3W90_RS09080	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
G3W90_RS09085	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
G3W90_RS09095	COG0436	Aminotransferase
G3W90_RS09110	COG1763	Mo-molybdopterin cofactor biosynthetic process
G3W90_RS09115	COG0303	'Molybdopterin
G3W90_RS09120	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
G3W90_RS09130	COG0314	molybdopterin synthase activity
G3W90_RS09135	COG0583	DNA-binding transcription factor activity
G3W90_RS09155	COG0542	response to heat
G3W90_RS09195	COG0431	NADPH-dependent FMN reductase
G3W90_RS09200	COG1393	Belongs to the ArsC family
G3W90_RS09220	COG3214	Protein conserved in bacteria
G3W90_RS09230	COG2084	Dehydrogenase
G3W90_RS09250	COG0673	inositol 2-dehydrogenase activity
G3W90_RS09275	COG3181	Tripartite tricarboxylate transporter family receptor
G3W90_RS09280	COG1309	transcriptional regulator
G3W90_RS09285	COG0028	Belongs to the TPP enzyme family
G3W90_RS09300	COG2224	Isocitrate lyase
G3W90_RS09305	COG2246	polysaccharide biosynthetic process
G3W90_RS09310	COG0546	phosphoglycolate phosphatase activity
G3W90_RS09310	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
G3W90_RS09320	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
G3W90_RS09325	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
G3W90_RS09330	COG0291	Belongs to the bacterial ribosomal protein bL35 family
G3W90_RS09335	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
G3W90_RS09340	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
G3W90_RS09345	COG0072	phenylalanine-tRNA ligase activity
G3W90_RS09345	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G3W90_RS09350	COG0776	regulation of translation
G3W90_RS09365	COG0582	viral genome integration into host DNA
G3W90_RS09395	COG4983	Phage plasmid primase, P4 family domain protein
G3W90_RS09420	COG0025	NhaP-type Na H and K H
G3W90_RS09425	COG0667	Aldo Keto reductase
G3W90_RS09435	COG0583	DNA-binding transcription factor activity
G3W90_RS09455	COG1960	acyl-CoA dehydrogenase activity
G3W90_RS09460	COG1024	Enoyl-CoA hydratase
G3W90_RS09465	COG0427	acetyl-CoA hydrolase
G3W90_RS09480	COG0583	DNA-binding transcription factor activity
G3W90_RS09485	COG1968	undecaprenyl-diphosphatase activity
G3W90_RS09510	COG1132	(ABC) transporter
G3W90_RS09515	COG3045	CreA protein
G3W90_RS09545	COG3243	poly(R)-hydroxyalkanoic acid synthase
G3W90_RS09550	COG0183	Belongs to the thiolase family
G3W90_RS09555	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G3W90_RS09560	COG0477	Major facilitator Superfamily
G3W90_RS09565	COG1028	Short-chain dehydrogenase reductase Sdr
G3W90_RS09570	COG1301	dicarboxylic acid transport
G3W90_RS09575	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
G3W90_RS09575	COG4651	solute:proton antiporter activity
G3W90_RS09590	COG1070	Carbohydrate kinase
G3W90_RS09595	COG4753	response regulator
G3W90_RS09595	COG2207	Transcriptional regulator
G3W90_RS09605	COG0246	Mannitol dehydrogenase
G3W90_RS09610	COG3842	ATPase activity
G3W90_RS09615	COG0395	ABC-type sugar transport system, permease component
G3W90_RS09620	COG1175	transmembrane transport
G3W90_RS09670	COG2165	general secretion pathway protein
G3W90_RS09735	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G3W90_RS09745	COG0747	negative chemotaxis
G3W90_RS09760	COG0747	negative chemotaxis
G3W90_RS09765	COG0601	transmembrane transport
G3W90_RS09770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G3W90_RS09785	COG1473	amidohydrolase
G3W90_RS09795	COG0745	RESPONSE REGULATOR receiver
G3W90_RS09820	COG2208	phosphoserine phosphatase activity
G3W90_RS09820	COG2770	Histidine kinase
G3W90_RS09845	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3W90_RS09865	COG1309	transcriptional regulator
G3W90_RS09880	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
G3W90_RS09885	COG1126	abc transporter atp-binding protein
G3W90_RS09890	COG0765	amino acid transport
G3W90_RS09900	COG1028	Short-chain dehydrogenase reductase Sdr
G3W90_RS09905	COG1802	Transcriptional regulator
G3W90_RS09910	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G3W90_RS09910	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G3W90_RS09915	COG1703	isobutyryl-CoA mutase activity
G3W90_RS09920	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G3W90_RS09925	COG4770	biotin carboxylase activity
G3W90_RS09940	COG2878	Part of a membrane complex involved in electron transport
G3W90_RS09955	COG0556	nucleotide-excision repair
G3W90_RS09960	COG1959	2 iron, 2 sulfur cluster binding
G3W90_RS09965	COG1104	cysteine desulfurase activity
G3W90_RS09970	COG0822	iron-sulfur transferase activity
G3W90_RS09980	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
G3W90_RS09985	COG0443	Heat shock 70 kDa protein
G3W90_RS09995	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
G3W90_RS10020	COG0167	dihydroorotate dehydrogenase activity
G3W90_RS10025	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
G3W90_RS10040	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
G3W90_RS10045	COG4566	intracellular signal transduction
G3W90_RS10050	COG4191	Histidine kinase
G3W90_RS10055	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
G3W90_RS10060	COG0508	dehydrogenase complex catalyzes the overall conversion of
G3W90_RS10065	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
G3W90_RS10070	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G3W90_RS10075	COG0791	NLP P60 protein
G3W90_RS10080	COG2133	pyrroloquinoline quinone binding
G3W90_RS10090	COG2368	4-hydroxyphenylacetate
G3W90_RS10115	COG0567	Dehydrogenase, E1 component
G3W90_RS10120	COG0508	dehydrogenase complex catalyzes the overall conversion of
G3W90_RS10125	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G3W90_RS10130	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
G3W90_RS10145	COG1199	ATP-dependent helicase activity
G3W90_RS10155	COG0564	pseudouridine synthase activity
G3W90_RS10160	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
G3W90_RS10165	COG1187	pseudouridine synthase activity
G3W90_RS10170	COG0105	UTP biosynthetic process
G3W90_RS10175	COG0820	rRNA (adenine-C2-)-methyltransferase activity
G3W90_RS10190	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
G3W90_RS10195	COG0124	histidyl-tRNA synthetase
G3W90_RS10205	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G3W90_RS10210	COG1160	GTP binding
G3W90_RS10215	COG1923	regulation of RNA biosynthetic process
G3W90_RS10220	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
G3W90_RS10225	COG0330	HflC and HflK could
G3W90_RS10230	COG0330	HflC and HflK could
G3W90_RS10235	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
G3W90_RS10240	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
G3W90_RS10245	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
G3W90_RS10255	COG0626	cystathionine gamma-synthase activity
G3W90_RS10270	COG1136	(ABC) transporter
G3W90_RS10275	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G3W90_RS10285	COG3618	amidohydrolase
G3W90_RS10290	COG1028	Short-chain dehydrogenase reductase Sdr
G3W90_RS10320	COG0667	Aldo Keto reductase
G3W90_RS10335	COG1295	ribonuclease BN
G3W90_RS10340	COG3119	arylsulfatase activity
G3W90_RS10350	COG0583	DNA-binding transcription factor activity
G3W90_RS10370	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
G3W90_RS10390	COG2951	lytic endotransglycosylase activity
G3W90_RS10405	COG0714	Associated with various cellular activities
G3W90_RS10415	COG1196	nuclear chromosome segregation
G3W90_RS10415	COG3264	Mechanosensitive ion channel
G3W90_RS10430	COG1960	acyl-CoA dehydrogenase activity
G3W90_RS10460	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
G3W90_RS10485	COG1414	Transcriptional regulator
G3W90_RS10490	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
G3W90_RS10500	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
G3W90_RS10510	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G3W90_RS10515	COG2814	Major facilitator Superfamily
G3W90_RS10540	COG0583	DNA-binding transcription factor activity
G3W90_RS10545	COG0477	Major facilitator Superfamily
G3W90_RS10560	COG1116	anion transmembrane transporter activity
G3W90_RS10580	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
G3W90_RS10610	COG3384	dioxygenase
G3W90_RS10630	COG3384	dioxygenase
G3W90_RS10645	COG4941	Belongs to the sigma-70 factor family
G3W90_RS10650	COG3795	YCII-related domain
G3W90_RS10670	COG3842	ATPase activity
G3W90_RS10695	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
G3W90_RS10695	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
G3W90_RS10700	COG0509	glycine decarboxylation via glycine cleavage system
G3W90_RS10705	COG0404	The glycine cleavage system catalyzes the degradation of glycine
G3W90_RS10720	COG1028	Short-chain dehydrogenase reductase Sdr
G3W90_RS10735	COG0642	Histidine kinase
G3W90_RS10740	COG0745	RESPONSE REGULATOR receiver
G3W90_RS10750	COG2194	sulfuric ester hydrolase activity
G3W90_RS10775	COG4302	ethanolamine ammonia-lyase activity
G3W90_RS10780	COG4303	Ethanolamine ammonia lyase large subunit
G3W90_RS10785	COG0545	Peptidyl-prolyl cis-trans isomerase
G3W90_RS10800	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
G3W90_RS10805	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
G3W90_RS10805	COG2169	Transcriptional regulator
G3W90_RS10840	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W90_RS10870	COG1024	Enoyl-CoA hydratase
G3W90_RS10880	COG0583	DNA-binding transcription factor activity
G3W90_RS10885	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
G3W90_RS10895	COG1396	sequence-specific DNA binding
G3W90_RS10895	COG3800	Transcriptional regulator
G3W90_RS10910	COG3181	Tripartite tricarboxylate transporter family receptor
G3W90_RS10935	COG2366	antibiotic biosynthetic process
G3W90_RS10940	COG1183	phosphatidylcholine synthase activity
G3W90_RS10945	COG0519	Catalyzes the synthesis of GMP from XMP
G3W90_RS10950	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
G3W90_RS10970	COG1132	(ABC) transporter
G3W90_RS10975	COG3384	dioxygenase
G3W90_RS11020	COG0587	DNA-directed DNA polymerase activity
G3W90_RS11030	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
G3W90_RS11035	COG4608	Belongs to the ABC transporter superfamily
G3W90_RS11040	COG0444	Belongs to the ABC transporter superfamily
G3W90_RS11045	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G3W90_RS11050	COG0601	transmembrane transport
G3W90_RS11055	COG0747	negative chemotaxis
G3W90_RS11085	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G3W90_RS11090	COG1028	Short-chain dehydrogenase reductase Sdr
G3W90_RS11140	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
G3W90_RS11155	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G3W90_RS11185	COG0220	tRNA (guanine-N7-)-methyltransferase activity
G3W90_RS11190	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G3W90_RS11195	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
G3W90_RS11195	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G3W90_RS11205	COG1741	Belongs to the pirin family
G3W90_RS11210	COG2259	Doxx family
G3W90_RS11220	COG1741	Belongs to the pirin family
G3W90_RS11240	COG0848	biopolymer transport protein
G3W90_RS11250	COG0824	Thioesterase
G3W90_RS11255	COG0436	Aminotransferase
G3W90_RS11260	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
G3W90_RS11265	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
G3W90_RS11280	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G3W90_RS11280	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G3W90_RS11315	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
G3W90_RS11320	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
G3W90_RS11325	COG0741	lytic transglycosylase activity
G3W90_RS11340	COG3228	Belongs to the MtfA family
G3W90_RS11345	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G3W90_RS11365	COG0215	cysteine-tRNA ligase activity
G3W90_RS11375	COG0825	malonyl-CoA metabolic process
G3W90_RS11380	COG0037	tRNA processing
G3W90_RS11395	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
G3W90_RS11395	COG2755	lipolytic protein G-D-S-L family
G3W90_RS11400	COG1609	Transcriptional regulator
G3W90_RS11405	COG1063	alcohol dehydrogenase
G3W90_RS11410	COG1070	Carbohydrate kinase
G3W90_RS11425	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G3W90_RS11425	COG1116	anion transmembrane transporter activity
G3W90_RS11430	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3W90_RS11450	COG1525	nuclease
G3W90_RS11460	COG1250	3-hydroxyacyl-CoA dehydrogenase
G3W90_RS11460	COG1024	Enoyl-CoA hydratase
G3W90_RS11465	COG0596	Alpha beta hydrolase
G3W90_RS11470	COG3321	synthase
G3W90_RS11470	COG0604	alcohol dehydrogenase
G3W90_RS11470	COG1028	Short-chain dehydrogenase reductase Sdr
G3W90_RS11500	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G3W90_RS11505	COG4638	Rieske (2fe-2S)
G3W90_RS11510	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
G3W90_RS11530	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
G3W90_RS11570	COG0411	ABC transporter
G3W90_RS11580	COG0318	PFAM AMP-dependent synthetase and ligase
G3W90_RS11585	COG1028	Short-chain dehydrogenase reductase Sdr
G3W90_RS11610	COG2326	polyphosphate kinase activity
G3W90_RS11620	COG0642	Histidine kinase
G3W90_RS11630	COG3181	Tripartite tricarboxylate transporter family receptor
G3W90_RS11655	COG2204	response regulator
G3W90_RS11670	COG1126	abc transporter atp-binding protein
G3W90_RS11695	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
G3W90_RS11700	COG1011	Hydrolase
G3W90_RS11710	COG2124	cytochrome p450
G3W90_RS11730	COG1028	Short-chain dehydrogenase reductase Sdr
G3W90_RS11770	COG1028	Short-chain dehydrogenase reductase Sdr
G3W90_RS11775	COG1028	Short-chain dehydrogenase reductase Sdr
G3W90_RS11795	COG2124	cytochrome p450
G3W90_RS11805	COG0559	Belongs to the binding-protein-dependent transport system permease family
G3W90_RS11825	COG3181	Tripartite tricarboxylate transporter family receptor
G3W90_RS11850	COG0655	NAD(P)H dehydrogenase (quinone) activity
G3W90_RS11865	COG0477	Major facilitator Superfamily
G3W90_RS11870	COG1028	Short-chain dehydrogenase reductase Sdr
G3W90_RS11880	COG2814	Major facilitator Superfamily
G3W90_RS11890	COG0318	PFAM AMP-dependent synthetase and ligase
G3W90_RS11920	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
G3W90_RS11940	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G3W90_RS11955	COG0544	peptidyl-prolyl cis-trans isomerase activity
G3W90_RS11960	COG0740	serine-type endopeptidase activity
G3W90_RS11965	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
G3W90_RS11970	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
G3W90_RS12005	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
G3W90_RS12020	COG0114	fumarate hydratase activity
G3W90_RS12030	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G3W90_RS12040	COG4654	Cytochrome c, class I
G3W90_RS12050	COG0129	dihydroxy-acid dehydratase activity
G3W90_RS12055	COG0583	DNA-binding transcription factor activity
G3W90_RS12060	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
G3W90_RS12070	COG0318	PFAM AMP-dependent synthetase and ligase
G3W90_RS12095	COG4206	TonB-dependent receptor
G3W90_RS12100	COG1797	cobyrinic acid a,c-diamide synthase activity
G3W90_RS12110	COG4607	ABC-type enterochelin transport system periplasmic component
G3W90_RS12115	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G3W90_RS12120	COG1121	(ABC) transporter
G3W90_RS12125	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
G3W90_RS12130	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
G3W90_RS12160	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G3W90_RS12170	COG1538	Outer membrane efflux protein
G3W90_RS12175	COG2188	Transcriptional regulator
G3W90_RS12185	COG1012	belongs to the aldehyde dehydrogenase family
G3W90_RS12195	COG3119	arylsulfatase activity
G3W90_RS12210	COG1492	cobalamin metabolic process
G3W90_RS12215	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
G3W90_RS12220	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
G3W90_RS12230	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
G3W90_RS12235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G3W90_RS12245	COG0626	cystathionine gamma-synthase activity
G3W90_RS12250	COG0560	Phosphoserine phosphatase
G3W90_RS12255	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
G3W90_RS12260	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
G3W90_RS12260	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
G3W90_RS12265	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
G3W90_RS12265	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
G3W90_RS12270	COG2205	protein histidine kinase activity
G3W90_RS12275	COG0745	RESPONSE REGULATOR receiver
G3W90_RS12290	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G3W90_RS12310	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
G3W90_RS12315	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
G3W90_RS12325	COG0557	exoribonuclease II activity
G3W90_RS12330	COG1028	Short-chain dehydrogenase reductase Sdr
G3W90_RS12350	COG0052	Belongs to the universal ribosomal protein uS2 family
G3W90_RS12355	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
G3W90_RS12360	COG0528	UMP kinase activity
G3W90_RS12365	COG0233	cytoplasmic translational termination
G3W90_RS12375	COG0575	Belongs to the CDS family
G3W90_RS12380	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
G3W90_RS12385	COG0750	zinc metalloprotease
G3W90_RS12400	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G3W90_RS12405	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
G3W90_RS12410	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G3W90_RS12415	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G3W90_RS12420	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
G3W90_RS12425	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G3W90_RS12430	COG0505	Belongs to the CarA family
G3W90_RS12435	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
G3W90_RS12445	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G3W90_RS12460	COG1534	Rna-binding protein
G3W90_RS12465	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
G3W90_RS12470	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G3W90_RS12480	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G3W90_RS12505	COG1024	Enoyl-CoA hydratase
G3W90_RS12510	COG1250	3-hydroxyacyl-CoA dehydrogenase
G3W90_RS12520	COG2814	Major facilitator Superfamily
G3W90_RS12525	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G3W90_RS12535	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
G3W90_RS12540	COG0252	asparaginase activity
G3W90_RS12545	COG0563	adenylate kinase activity
G3W90_RS12550	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
G3W90_RS12555	COG2835	tetraacyldisaccharide 4'-kinase activity
G3W90_RS12560	COG1663	tetraacyldisaccharide 4'-kinase activity
G3W90_RS12565	COG0848	biopolymer transport protein
G3W90_RS12570	COG0811	peptide transport
G3W90_RS12580	COG1570	exodeoxyribonuclease VII activity
G3W90_RS12585	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
G3W90_RS12605	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
G3W90_RS12610	COG0542	response to heat
G3W90_RS12615	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G3W90_RS12620	COG2925	Exonuclease
G3W90_RS12635	COG0456	acetyltransferase
G3W90_RS12650	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G3W90_RS12660	COG5002	protein histidine kinase activity
G3W90_RS12675	COG3038	cytochrome b561
G3W90_RS12695	COG0402	S-adenosylhomocysteine deaminase activity
G3W90_RS12700	COG0583	DNA-binding transcription factor activity
G3W90_RS12710	COG1024	Enoyl-CoA hydratase
G3W90_RS12725	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3W90_RS12740	COG3300	MHYT domain
G3W90_RS12740	COG5001	Diguanylate cyclase
G3W90_RS12745	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
G3W90_RS12760	COG0433	COG0433 Predicted ATPase
G3W90_RS12775	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
G3W90_RS12810	COG1028	Short-chain dehydrogenase reductase Sdr
G3W90_RS12835	COG0217	transcriptional regulatory protein
G3W90_RS12840	COG0151	Belongs to the GarS family
G3W90_RS12845	COG0408	coproporphyrinogen oxidase activity
G3W90_RS12850	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
G3W90_RS12855	COG0799	negative regulation of ribosome biogenesis
G3W90_RS12860	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
G3W90_RS12865	COG0424	maF-like protein
G3W90_RS12870	COG1530	ribonuclease E activity
G3W90_RS12875	COG1132	(ABC) transporter
G3W90_RS12880	COG0823	Involved in the tonB-independent uptake of proteins
G3W90_RS12885	COG2885	chlorophyll binding
G3W90_RS12895	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
G3W90_RS12905	COG0583	DNA-binding transcription factor activity
G3W90_RS12930	COG2890	protein-(glutamine-N5) methyltransferase activity
G3W90_RS12935	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G3W90_RS12945	COG2171	N-acyltransferase activity
G3W90_RS12950	COG0436	Aminotransferase
G3W90_RS12955	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
G3W90_RS12955	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
G3W90_RS12960	COG1643	Atp-dependent helicase
G3W90_RS12975	COG0436	Aminotransferase
G3W90_RS12980	COG0583	DNA-binding transcription factor activity
G3W90_RS12995	COG0795	lipopolysaccharide-transporting ATPase activity
G3W90_RS13000	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
G3W90_RS13035	COG0612	Peptidase, M16
G3W90_RS13040	COG0582	viral genome integration into host DNA
G3W90_RS13170	COG1982	Orn Lys Arg decarboxylase major
G3W90_RS13175	COG1793	dna ligase
G3W90_RS13180	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
G3W90_RS13185	COG4166	transmembrane transport
G3W90_RS13190	COG4174	ABC transporter (Permease)
G3W90_RS13195	COG4239	(ABC) transporter, permease
G3W90_RS13200	COG4172	Belongs to the ABC transporter superfamily
G3W90_RS13205	COG0477	Major facilitator Superfamily
G3W90_RS13210	COG0779	Required for maturation of 30S ribosomal subunits
G3W90_RS13215	COG2251	uridine kinase activity
G3W90_RS13215	COG0195	Participates in both transcription termination and antitermination
G3W90_RS13220	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
G3W90_RS13225	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
G3W90_RS13230	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
G3W90_RS13265	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
G3W90_RS13270	COG2867	negative regulation of translational initiation
G3W90_RS13290	COG0519	Catalyzes the synthesis of GMP from XMP
G3W90_RS13290	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G3W90_RS13295	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
G3W90_RS13300	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
G3W90_RS13345	COG1619	proteins homologs of microcin C7 resistance protein MccF
G3W90_RS13365	COG3158	transport of potassium into the cell
G3W90_RS13375	COG0084	hydrolase, TatD family'
G3W90_RS13390	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
G3W90_RS13395	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
G3W90_RS13435	COG2183	response to ionizing radiation
G3W90_RS13450	COG0534	Mate efflux family protein
G3W90_RS13525	COG0477	Major facilitator Superfamily
G3W90_RS13530	COG2814	Major facilitator Superfamily
G3W90_RS13535	COG2814	Major facilitator Superfamily
G3W90_RS13565	COG1960	acyl-CoA dehydrogenase activity
G3W90_RS13570	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
G3W90_RS13575	COG4638	Rieske (2fe-2S)
G3W90_RS13590	COG1028	Short-chain dehydrogenase reductase Sdr
G3W90_RS13605	COG3008	intermembrane lipid transfer
G3W90_RS13605	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G3W90_RS13610	COG2995	paraquat-inducible protein a
G3W90_RS13615	COG2995	paraquat-inducible protein a
G3W90_RS13625	COG5507	3-demethylubiquinone-9 3-methyltransferase
G3W90_RS13640	COG1960	acyl-CoA dehydrogenase activity
G3W90_RS13645	COG2130	NADP-dependent
G3W90_RS13665	COG1960	acyl-CoA dehydrogenase activity
G3W90_RS13680	COG0183	Belongs to the thiolase family
G3W90_RS13685	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G3W90_RS13690	COG1250	3-hydroxyacyl-CoA dehydrogenase
G3W90_RS13690	COG1024	Enoyl-CoA hydratase
G3W90_RS13695	COG1129	ABC transporter
G3W90_RS13700	COG0411	ABC transporter
G3W90_RS13725	COG0318	PFAM AMP-dependent synthetase and ligase
G3W90_RS13730	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
G3W90_RS13735	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G3W90_RS13740	COG2917	probably involved in intracellular septation
G3W90_RS13750	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G3W90_RS13755	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
G3W90_RS13755	COG0047	phosphoribosylformylglycinamidine synthase activity
G3W90_RS13760	COG0024	Methionine aminopeptidase
G3W90_RS13765	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
G3W90_RS13770	COG0765	amino acid transport
G3W90_RS13775	COG4597	amino acid ABC transporter
G3W90_RS13780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G3W90_RS13785	COG2259	Doxx family
G3W90_RS13790	COG0242	peptide deformylase activity
G3W90_RS13800	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
G3W90_RS13810	COG1196	nuclear chromosome segregation
G3W90_RS13825	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
G3W90_RS13830	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
G3W90_RS13835	COG4208	sulfate ABC transporter
G3W90_RS13845	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
G3W90_RS13855	COG0450	alkyl hydroperoxide reductase
G3W90_RS13865	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
G3W90_RS13870	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G3W90_RS13885	COG1045	serine acetyltransferase
G3W90_RS13895	COG1116	anion transmembrane transporter activity
G3W90_RS13900	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3W90_RS13905	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G3W90_RS13910	COG0431	NADPH-dependent FMN reductase
G3W90_RS13915	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
G3W90_RS13920	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
G3W90_RS13925	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G3W90_RS13925	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
G3W90_RS13935	COG1272	protein, Hemolysin III
G3W90_RS13945	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
G3W90_RS13950	COG3383	formate dehydrogenase (NAD+) activity
G3W90_RS13990	COG0175	sulfate reduction
G3W90_RS13995	COG0175	sulfate reduction
G3W90_RS14000	COG2895	sulfate adenylyltransferase (ATP) activity
G3W90_RS14005	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
G3W90_RS14010	COG0492	ferredoxin-NADP+ reductase activity
G3W90_RS14015	COG0671	phosphoesterase, PA-phosphatase related
G3W90_RS14025	COG0351	phosphomethylpyrimidine kinase
G3W90_RS14040	COG2022	thiamine diphosphate biosynthetic process
G3W90_RS14050	COG2755	lipolytic protein G-D-S-L family
G3W90_RS14050	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
G3W90_RS14080	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G3W90_RS14105	COG0318	PFAM AMP-dependent synthetase and ligase
G3W90_RS14115	COG2175	clavaminate synthase activity
G3W90_RS14135	COG1024	Enoyl-CoA hydratase
G3W90_RS14140	COG1960	acyl-CoA dehydrogenase activity
G3W90_RS14145	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W90_RS14160	COG1024	Enoyl-CoA hydratase
G3W90_RS14185	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G3W90_RS14190	COG0642	Histidine kinase
G3W90_RS14195	COG0745	RESPONSE REGULATOR receiver
G3W90_RS14200	COG1414	Transcriptional regulator
G3W90_RS14205	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G3W90_RS14215	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
G3W90_RS14220	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
G3W90_RS14225	COG1414	Transcriptional regulator
G3W90_RS14235	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G3W90_RS14240	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G3W90_RS14245	COG1183	phosphatidylcholine synthase activity
G3W90_RS14250	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
G3W90_RS14255	COG0440	acetolactate synthase activity
G3W90_RS14260	COG0028	Belongs to the TPP enzyme family
G3W90_RS14285	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
G3W90_RS14295	COG0347	Belongs to the P(II) protein family
G3W90_RS14315	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
G3W90_RS14345	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G3W90_RS14355	COG1012	belongs to the aldehyde dehydrogenase family
G3W90_RS14390	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
G3W90_RS14395	COG0746	molybdenum cofactor guanylyltransferase activity
G3W90_RS14405	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G3W90_RS14405	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G3W90_RS14410	COG0328	RNA-DNA hybrid ribonuclease activity
G3W90_RS14425	COG1388	LysM domain
G3W90_RS14425	COG0741	lytic transglycosylase activity
G3W90_RS14430	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3W90_RS14440	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G3W90_RS14450	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
G3W90_RS14455	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
G3W90_RS14460	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
G3W90_RS14675	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
G3W90_RS14675	COG0493	'glutamate synthase
G3W90_RS14680	COG1074	ATP-dependent DNA helicase activity
G3W90_RS14695	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
G3W90_RS14700	COG0673	inositol 2-dehydrogenase activity
G3W90_RS14705	COG0254	rRNA binding
G3W90_RS14715	COG0534	Mate efflux family protein
G3W90_RS14720	COG5002	protein histidine kinase activity
G3W90_RS14735	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
G3W90_RS14740	COG0581	inorganic phosphate transmembrane transporter activity
G3W90_RS14745	COG0573	inorganic phosphate transmembrane transporter activity
G3W90_RS14750	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
G3W90_RS14755	COG0248	Ppx GppA phosphatase
G3W90_RS14775	COG3634	alkyl hydroperoxide reductase activity
G3W90_RS14780	COG0625	glutathione transferase activity
G3W90_RS14800	COG0583	DNA-binding transcription factor activity
G3W90_RS14815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G3W90_RS14820	COG0765	amino acid transport
G3W90_RS14825	COG0765	amino acid transport
G3W90_RS14840	COG1082	Xylose isomerase domain protein TIM barrel
G3W90_RS14845	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G3W90_RS14850	COG0698	ribose 5-phosphate isomerase
G3W90_RS14870	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3W90_RS14875	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G3W90_RS14895	COG1522	sequence-specific DNA binding
G3W90_RS14910	COG4993	Dehydrogenase
G3W90_RS14915	COG3491	Belongs to the iron ascorbate-dependent oxidoreductase family
G3W90_RS14935	COG2188	Transcriptional regulator
G3W90_RS14945	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3W90_RS14960	COG1028	Short-chain dehydrogenase reductase Sdr
G3W90_RS14970	COG0183	Belongs to the thiolase family
G3W90_RS14980	COG0439	Biotin carboxylase
G3W90_RS15000	COG0156	8-amino-7-oxononanoate synthase activity
G3W90_RS15010	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
G3W90_RS15015	COG2124	cytochrome p450
G3W90_RS15020	COG1309	transcriptional regulator
G3W90_RS15025	COG1172	Belongs to the binding-protein-dependent transport system permease family
G3W90_RS15035	COG0410	ABC transporter
G3W90_RS15040	COG0411	ABC transporter
G3W90_RS15050	COG1335	isochorismatase
G3W90_RS15080	COG0583	DNA-binding transcription factor activity
G3W90_RS15085	COG0277	FAD linked oxidase domain protein
G3W90_RS15090	COG0277	FAD linked oxidase domain protein
G3W90_RS15095	COG0247	lactate metabolic process
G3W90_RS15105	COG3119	arylsulfatase activity
G3W90_RS15140	COG2149	membrane
G3W90_RS15155	COG0726	polysaccharide deacetylase
G3W90_RS15180	COG2076	Multidrug Resistance protein
G3W90_RS15185	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
G3W90_RS15195	COG0667	Aldo Keto reductase
G3W90_RS15210	COG3181	Tripartite tricarboxylate transporter family receptor
G3W90_RS15225	COG1028	Short-chain dehydrogenase reductase Sdr
G3W90_RS15260	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
G3W90_RS15265	COG0366	Alpha amylase catalytic
G3W90_RS15285	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
G3W90_RS15290	COG1640	4-alpha-glucanotransferase
G3W90_RS15300	COG1414	Transcriptional regulator
G3W90_RS15310	COG0243	molybdopterin cofactor binding
G3W90_RS15320	COG1024	Enoyl-CoA hydratase
G3W90_RS15325	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W90_RS15330	COG3181	Tripartite tricarboxylate transporter family receptor
G3W90_RS15335	COG0318	PFAM AMP-dependent synthetase and ligase
G3W90_RS15350	COG0318	PFAM AMP-dependent synthetase and ligase
G3W90_RS15360	COG1024	Enoyl-CoA hydratase
G3W90_RS15410	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
G3W90_RS15415	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W90_RS15420	COG3181	Tripartite tricarboxylate transporter family receptor
G3W90_RS15430	COG1024	Enoyl-CoA hydratase
G3W90_RS15450	COG0473	3-isopropylmalate dehydrogenase activity
G3W90_RS15450	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G3W90_RS15500	COG1053	succinate dehydrogenase
G3W90_RS15505	COG0318	PFAM AMP-dependent synthetase and ligase
G3W90_RS15520	COG4221	oxidoreductase activity
G3W90_RS15555	COG1028	Short-chain dehydrogenase reductase Sdr
G3W90_RS15560	COG4689	acetoacetate decarboxylase
G3W90_RS15595	COG2188	Transcriptional regulator
G3W90_RS15615	COG0765	amino acid transport
G3W90_RS15620	COG0765	amino acid transport
G3W90_RS15630	COG1126	abc transporter atp-binding protein
G3W90_RS15635	COG3181	Tripartite tricarboxylate transporter family receptor
G3W90_RS15640	COG0006	proline dipeptidase activity
G3W90_RS15660	COG2308	Evidence 4 Homologs of previously reported genes of
G3W90_RS15680	COG1305	Transglutaminase-like
G3W90_RS15690	COG1522	sequence-specific DNA binding
G3W90_RS15700	COG1280	lysine exporter protein (LysE YggA)
G3W90_RS15705	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
G3W90_RS15725	COG1012	belongs to the aldehyde dehydrogenase family
G3W90_RS15735	COG1024	Enoyl-CoA hydratase
G3W90_RS15740	COG1609	Transcriptional regulator
G3W90_RS15750	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G3W90_RS15760	COG1126	abc transporter atp-binding protein
G3W90_RS15775	COG0765	amino acid transport
G3W90_RS15810	COG0741	lytic transglycosylase activity
G3W90_RS15810	COG1196	nuclear chromosome segregation
G3W90_RS15810	COG0739	heme binding
G3W90_RS15855	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G3W90_RS15860	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
G3W90_RS15865	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
G3W90_RS15880	COG2850	peptidyl-arginine hydroxylation
G3W90_RS15885	COG1047	Peptidyl-prolyl cis-trans
G3W90_RS15900	COG0583	DNA-binding transcription factor activity
G3W90_RS15905	COG0756	dUTP diphosphatase activity
G3W90_RS15915	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
G3W90_RS15920	COG0504	CTP synthase activity
G3W90_RS15925	COG2877	3-deoxy-8-phosphooctulonate synthase activity
G3W90_RS15935	COG0148	phosphopyruvate hydratase activity
G3W90_RS15940	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
G3W90_RS15955	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
G3W90_RS15965	COG2833	Protein of unknown function (DUF455)
G3W90_RS15980	COG4974	Belongs to the 'phage' integrase family
G3W90_RS15985	COG3181	Tripartite tricarboxylate transporter family receptor
G3W90_RS16000	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
G3W90_RS16005	COG0802	atpase or kinase
G3W90_RS16010	COG0860	N-Acetylmuramoyl-L-alanine amidase
G3W90_RS16030	COG0586	Pfam SNARE associated Golgi protein
G3W90_RS16035	COG1028	Short-chain dehydrogenase reductase Sdr
G3W90_RS16045	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
G3W90_RS16055	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
G3W90_RS16060	COG4181	ATPase activity
G3W90_RS16065	COG0583	DNA-binding transcription factor activity
G3W90_RS16100	COG0583	DNA-binding transcription factor activity
G3W90_RS16120	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
G3W90_RS16130	COG3795	YCII-related domain
G3W90_RS16135	COG4941	Belongs to the sigma-70 factor family
G3W90_RS16180	COG2814	Major facilitator Superfamily
G3W90_RS16185	COG1566	PFAM secretion protein HlyD family protein
G3W90_RS16190	COG1538	Outer membrane efflux protein
G3W90_RS16195	COG1846	Transcriptional regulator
G3W90_RS16200	COG1132	(ABC) transporter
G3W90_RS16210	COG0494	nUDIX hydrolase
G3W90_RS16220	COG1007	ATP synthesis coupled electron transport
G3W90_RS16235	COG0713	ATP synthesis coupled electron transport
G3W90_RS16245	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G3W90_RS16250	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
G3W90_RS16255	COG1034	ATP synthesis coupled electron transport
G3W90_RS16270	COG0649	NAD binding
G3W90_RS16275	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G3W90_RS16280	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G3W90_RS16285	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G3W90_RS16300	COG0149	triose-phosphate isomerase activity
G3W90_RS16305	COG0604	alcohol dehydrogenase
G3W90_RS16305	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G3W90_RS16305	COG3321	synthase
G3W90_RS16305	COG4221	oxidoreductase activity
G3W90_RS16310	COG1185	polyribonucleotide nucleotidyltransferase activity
G3W90_RS16315	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
G3W90_RS16320	COG0436	Aminotransferase
G3W90_RS16325	COG0683	leucine binding
G3W90_RS16340	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
G3W90_RS16345	COG3707	response regulator
G3W90_RS16350	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G3W90_RS16355	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3W90_RS16360	COG1116	anion transmembrane transporter activity
G3W90_RS16370	COG2223	nitrite transmembrane transporter activity
G3W90_RS16375	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G3W90_RS16385	COG0243	molybdopterin cofactor binding
G3W90_RS16390	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
G3W90_RS16405	COG2081	HI0933 family
G3W90_RS16410	COG0828	Belongs to the bacterial ribosomal protein bS21 family
G3W90_RS16415	COG1610	YqeY-like protein
G3W90_RS16425	COG0312	modulator of DNA gyrase
G3W90_RS16430	COG3028	Belongs to the UPF0307 family
G3W90_RS16435	COG0521	Mo-molybdopterin cofactor biosynthetic process
G3W90_RS16440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G3W90_RS16450	COG0765	amino acid transport
G3W90_RS16455	COG0765	amino acid transport
G3W90_RS16460	COG4221	oxidoreductase activity
G3W90_RS16465	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
G3W90_RS16475	COG1984	allophanate hydrolase subunit 2
G3W90_RS16480	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
G3W90_RS16490	COG0511	ligase activity, forming carbon-carbon bonds
G3W90_RS16500	COG0436	Aminotransferase
G3W90_RS16505	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G3W90_RS16565	COG0436	Aminotransferase
G3W90_RS16575	COG3265	gluconokinase activity
G3W90_RS16580	COG1028	Short-chain dehydrogenase reductase Sdr
G3W90_RS16585	COG1063	alcohol dehydrogenase
G3W90_RS16590	COG1045	serine acetyltransferase
G3W90_RS16605	COG1289	transmembrane transporter activity
G3W90_RS16625	COG2375	cellular response to nickel ion
G3W90_RS16650	COG2159	amidohydrolase
G3W90_RS16670	COG0583	DNA-binding transcription factor activity
G3W90_RS16675	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
G3W90_RS16690	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G3W90_RS16700	COG0583	DNA-binding transcription factor activity
G3W90_RS16705	COG3119	arylsulfatase activity
G3W90_RS16710	COG3181	Tripartite tricarboxylate transporter family receptor
G3W90_RS16715	COG1968	undecaprenyl-diphosphatase activity
G3W90_RS16725	COG3246	L-lysine catabolic process to acetate
G3W90_RS16735	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W90_RS16740	COG2301	Belongs to the HpcH HpaI aldolase family
G3W90_RS16760	COG1802	Transcriptional regulator
G3W90_RS16770	COG1024	Enoyl-CoA hydratase
G3W90_RS16785	COG1360	Flagellar Motor Protein
G3W90_RS16815	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G3W90_RS16820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G3W90_RS16845	COG2972	Histidine kinase
G3W90_RS16860	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G3W90_RS16885	COG0411	ABC transporter
G3W90_RS16910	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
G3W90_RS16925	COG1028	Short-chain dehydrogenase reductase Sdr
G3W90_RS16935	COG2918	glutathione biosynthetic process
G3W90_RS16940	COG0400	carboxylic ester hydrolase activity
G3W90_RS16950	COG0583	DNA-binding transcription factor activity
G3W90_RS17015	COG2354	Protein conserved in bacteria
G3W90_RS17025	COG4628	conserved protein (DUF2132)
G3W90_RS17040	COG0564	pseudouridine synthase activity
G3W90_RS17045	COG0589	response to stress
G3W90_RS17060	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
G3W90_RS17065	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G3W90_RS17070	COG1252	NADH dehydrogenase
G3W90_RS17080	COG0318	PFAM AMP-dependent synthetase and ligase
G3W90_RS17085	COG1764	response to oxidative stress
G3W90_RS17100	COG0789	Transcriptional regulator
G3W90_RS17110	COG3191	aminopeptidase activity
G3W90_RS17140	COG0488	(ABC) transporter
G3W90_RS17145	COG0513	Belongs to the DEAD box helicase family
G3W90_RS17150	COG3842	ATPase activity
G3W90_RS17160	COG1175	transmembrane transport
G3W90_RS17170	COG2186	Transcriptional regulator
G3W90_RS17175	COG3734	2-keto-3-deoxy-galactonokinase
G3W90_RS17180	COG0800	Aldolase
G3W90_RS17190	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
G3W90_RS17205	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
G3W90_RS17210	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G3W90_RS17270	COG1595	DNA-templated transcription, initiation
G3W90_RS17280	COG3474	cytochrome
G3W90_RS17285	COG0302	gtp cyclohydrolase
G3W90_RS17290	COG1028	Short-chain dehydrogenase reductase Sdr
G3W90_RS17315	COG0346	lactoylglutathione lyase activity
G3W90_RS17330	COG0800	Aldolase
G3W90_RS17360	COG0259	pyridoxamine-phosphate oxidase activity
G3W90_RS17375	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G3W90_RS17380	COG2301	Belongs to the HpcH HpaI aldolase family
G3W90_RS17410	COG4772	TonB-dependent receptor
G3W90_RS17420	COG2986	histidine ammonia-lyase
G3W90_RS17425	COG1309	transcriptional regulator
G3W90_RS17430	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
G3W90_RS17445	COG2207	Transcriptional regulator
G3W90_RS17450	COG0318	PFAM AMP-dependent synthetase and ligase
G3W90_RS17460	COG2030	dehydratase
G3W90_RS17485	COG0235	Class ii aldolase
G3W90_RS17530	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G3W90_RS17535	COG2863	cytochrome
G3W90_RS17540	COG1529	Aldehyde oxidase and xanthine dehydrogenase
G3W90_RS17540	COG2010	Cytochrome c
G3W90_RS17555	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G3W90_RS17560	COG1309	transcriptional regulator
G3W90_RS17575	COG1132	(ABC) transporter
G3W90_RS17590	COG2217	Heavy metal translocating P-type atpase
G3W90_RS17595	COG0789	Transcriptional regulator
G3W90_RS17645	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
G3W90_RS17650	COG2301	Belongs to the HpcH HpaI aldolase family
G3W90_RS17670	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G3W90_RS17685	COG1286	toxin biosynthetic process
G3W90_RS17695	COG0285	dihydrofolate synthase activity
G3W90_RS17700	COG1393	Belongs to the ArsC family
G3W90_RS17710	COG3123	guanosine phosphorylase activity
G3W90_RS17715	COG0137	argininosuccinate synthase activity
G3W90_RS17720	COG0812	UDP-N-acetylmuramate dehydrogenase activity
G3W90_RS17725	COG1666	GTP binding
G3W90_RS17735	COG0251	oxidation-reduction process
G3W90_RS17740	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
G3W90_RS17745	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
G3W90_RS17750	COG0667	Aldo Keto reductase
G3W90_RS17760	COG3437	response regulator, receiver
G3W90_RS17760	COG4999	Histidine kinase
G3W90_RS17760	COG2205	protein histidine kinase activity
G3W90_RS17760	COG3850	Histidine kinase
G3W90_RS17765	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
G3W90_RS17785	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G3W90_RS17790	COG0308	aminopeptidase N
G3W90_RS17795	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
G3W90_RS17815	COG3181	Tripartite tricarboxylate transporter family receptor
G3W90_RS17820	COG0583	DNA-binding transcription factor activity
G3W90_RS17825	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
G3W90_RS17830	COG1301	dicarboxylic acid transport
G3W90_RS17845	COG0745	RESPONSE REGULATOR receiver
G3W90_RS17850	COG2205	protein histidine kinase activity
G3W90_RS17865	COG0840	transmembrane signaling receptor activity
G3W90_RS17870	COG0745	RESPONSE REGULATOR receiver
G3W90_RS17885	COG0840	transmembrane signaling receptor activity
G3W90_RS17890	COG0835	chemotaxis
G3W90_RS17920	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
G3W90_RS17925	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
G3W90_RS17930	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
G3W90_RS17935	COG0745	RESPONSE REGULATOR receiver
G3W90_RS17945	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
G3W90_RS17950	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
G3W90_RS17960	COG2198	Histidine kinase
G3W90_RS17960	COG0643	Histidine kinase
G3W90_RS18005	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
G3W90_RS18015	COG1677	Flagellar hook-basal body complex protein FliE
G3W90_RS18020	COG1766	The M ring may be actively involved in energy transduction
G3W90_RS18025	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
G3W90_RS18045	COG3144	bacterial-type flagellum assembly
G3W90_RS18050	COG1580	Controls the rotational direction of flagella during chemotaxis
G3W90_RS18055	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
G3W90_RS18070	COG1338	Plays a role in the flagellum-specific transport system
G3W90_RS18075	COG1987	bacterial-type flagellum assembly
G3W90_RS18095	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G3W90_RS18125	COG1256	bacterial-type flagellum assembly
G3W90_RS18130	COG0840	transmembrane signaling receptor activity
G3W90_RS18140	COG0835	chemotaxis
G3W90_RS18145	COG0840	transmembrane signaling receptor activity
G3W90_RS18150	COG0835	chemotaxis
G3W90_RS18155	COG3951	Flagellar rod assembly protein muramidase FlgJ
G3W90_RS18155	COG1705	Flagellar rod assembly protein muramidase FlgJ
G3W90_RS18160	COG1706	bacterial-type flagellum-dependent cell motility
G3W90_RS18165	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
G3W90_RS18170	COG4786	Flagellar basal body rod
G3W90_RS18185	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
G3W90_RS18190	COG1558	bacterial-type flagellum-dependent cell motility
G3W90_RS18195	COG1815	bacterial-type flagellum-dependent cell motility
G3W90_RS18220	COG0604	alcohol dehydrogenase
G3W90_RS18225	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
G3W90_RS18245	COG0583	DNA-binding transcription factor activity
G3W90_RS18250	COG1028	Short-chain dehydrogenase reductase Sdr
G3W90_RS18270	COG3302	dmso reductase anchor subunit
G3W90_RS18275	COG0437	4 iron, 4 sulfur cluster binding
G3W90_RS18280	COG0243	molybdopterin cofactor binding
G3W90_RS18285	COG0583	DNA-binding transcription factor activity
G3W90_RS18310	COG1414	Transcriptional regulator
G3W90_RS18335	COG1012	belongs to the aldehyde dehydrogenase family
G3W90_RS18340	COG0318	PFAM AMP-dependent synthetase and ligase
G3W90_RS18360	COG1028	Short-chain dehydrogenase reductase Sdr
G3W90_RS18365	COG0179	Fumarylacetoacetate (FAA) hydrolase
G3W90_RS18370	COG3181	Tripartite tricarboxylate transporter family receptor
G3W90_RS18385	COG1414	Transcriptional regulator
G3W90_RS18390	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
G3W90_RS18395	COG0477	Major facilitator Superfamily
G3W90_RS18400	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3W90_RS18405	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
G3W90_RS18410	COG4521	taurine ABC transporter
G3W90_RS18415	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G3W90_RS18435	COG0601	transmembrane transport
G3W90_RS18440	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G3W90_RS18445	COG0444	Belongs to the ABC transporter superfamily
G3W90_RS18450	COG4608	Belongs to the ABC transporter superfamily
G3W90_RS18470	COG0247	lactate metabolic process
G3W90_RS18475	COG1592	Rubrerythrin
G3W90_RS18485	COG2197	response regulator
G3W90_RS18490	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G3W90_RS18495	COG1253	flavin adenine dinucleotide binding
G3W90_RS18500	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
G3W90_RS18505	COG0513	Belongs to the DEAD box helicase family
G3W90_RS18510	COG2321	neutral zinc metallopeptidase
G3W90_RS18520	COG0717	Belongs to the dCTP deaminase family
G3W90_RS18525	COG0402	S-adenosylhomocysteine deaminase activity
G3W90_RS18545	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
G3W90_RS18570	COG2252	PERMEase
G3W90_RS18580	COG1529	Aldehyde oxidase and xanthine dehydrogenase
G3W90_RS18605	COG1850	ribulose-bisphosphate carboxylase activity
G3W90_RS18615	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
G3W90_RS18620	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G3W90_RS18625	COG1609	Transcriptional regulator
G3W90_RS18640	COG1024	Enoyl-CoA hydratase
G3W90_RS18645	COG3181	Tripartite tricarboxylate transporter family receptor
G3W90_RS18650	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W90_RS18655	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G3W90_RS18675	COG0667	Aldo Keto reductase
G3W90_RS18715	COG0438	transferase activity, transferring glycosyl groups
G3W90_RS18745	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
G3W90_RS18745	COG3608	succinylglutamate desuccinylase aspartoacylase
G3W90_RS18790	COG0667	Aldo Keto reductase
G3W90_RS18820	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W90_RS18825	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G3W90_RS18860	COG2084	Dehydrogenase
G3W90_RS18865	COG0745	RESPONSE REGULATOR receiver
G3W90_RS18870	COG0642	Histidine kinase
G3W90_RS18885	COG0671	phosphoesterase, PA-phosphatase related
G3W90_RS18890	COG0463	Glycosyl transferase, family 2
G3W90_RS18895	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
G3W90_RS18905	COG1116	anion transmembrane transporter activity
G3W90_RS18910	COG0390	transport system, permease component
G3W90_RS18920	COG1609	Transcriptional regulator
G3W90_RS18940	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G3W90_RS18950	COG1950	PFAM Membrane protein of
G3W90_RS18955	COG1012	belongs to the aldehyde dehydrogenase family
G3W90_RS18960	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
G3W90_RS18965	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G3W90_RS18980	COG1122	ATPase activity
G3W90_RS19000	COG0559	Belongs to the binding-protein-dependent transport system permease family
G3W90_RS19010	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G3W90_RS19015	COG2151	metal-sulfur cluster biosynthetic enzyme
G3W90_RS19020	COG3396	Phenylacetate-CoA oxygenase
G3W90_RS19025	COG3460	Phenylacetate-CoA oxygenase
G3W90_RS19030	COG3396	Phenylacetate-CoA oxygenase
G3W90_RS19040	COG2050	protein possibly involved in aromatic compounds catabolism
G3W90_RS19045	COG1024	Enoyl-CoA hydratase
G3W90_RS19055	COG1309	transcriptional regulator
G3W90_RS19065	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
G3W90_RS19115	COG2188	Transcriptional regulator
G3W90_RS19120	COG2070	2-Nitropropane dioxygenase
G3W90_RS19130	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3W90_RS19135	COG1116	anion transmembrane transporter activity
G3W90_RS19150	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
G3W90_RS19165	COG0392	lysyltransferase activity
G3W90_RS19170	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
G3W90_RS19175	COG0142	geranyltranstransferase activity
G3W90_RS19180	COG1722	exodeoxyribonuclease VII activity
G3W90_RS19225	COG3360	Dodecin
G3W90_RS19270	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
G3W90_RS19280	COG1012	belongs to the aldehyde dehydrogenase family
G3W90_RS19285	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
G3W90_RS19305	COG1176	ABC-type spermidine putrescine transport system, permease component I
G3W90_RS19310	COG3842	ATPase activity
G3W90_RS19315	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
G3W90_RS19325	COG0210	DNA helicase
G3W90_RS19330	COG0516	GMP reductase activity
G3W90_RS19345	COG1028	Short-chain dehydrogenase reductase Sdr
G3W90_RS19355	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G3W90_RS19360	COG1012	belongs to the aldehyde dehydrogenase family
G3W90_RS19375	COG4993	Dehydrogenase
G3W90_RS19375	COG2010	Cytochrome c
G3W90_RS19390	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
G3W90_RS19395	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
G3W90_RS19405	COG0535	radical SAM domain protein
G3W90_RS19410	COG0842	Transport permease protein
G3W90_RS19410	COG1129	ABC transporter
G3W90_RS19435	COG3901	Regulator of nitric oxide reductase transcription
G3W90_RS19435	COG0348	domain, Protein
G3W90_RS19455	COG3851	Histidine kinase
G3W90_RS19495	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
G3W90_RS19500	COG0028	Belongs to the TPP enzyme family
G3W90_RS19530	COG0513	Belongs to the DEAD box helicase family
G3W90_RS19535	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
G3W90_RS19540	COG0501	Belongs to the peptidase M48B family
G3W90_RS19545	COG2154	pterin-4-alpha-carbinolamine dehydratase
G3W90_RS19550	COG1162	GTPase activity
G3W90_RS19555	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
G3W90_RS19560	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
G3W90_RS19570	COG0335	large ribosomal subunit rRNA binding
G3W90_RS19575	COG0336	Belongs to the RNA methyltransferase TrmD family
G3W90_RS19580	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
G3W90_RS19585	COG0228	four-way junction DNA binding
G3W90_RS19600	COG0306	phosphate transporter
G3W90_RS19605	COG1392	Phosphate transport regulator
G3W90_RS19615	COG0617	tRNA 3'-terminal CCA addition
G3W90_RS19620	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
G3W90_RS19625	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
G3W90_RS19640	COG4977	sequence-specific DNA binding
G3W90_RS19640	COG1917	Cupin 2, conserved barrel domain protein
G3W90_RS19645	COG1289	transmembrane transporter activity
G3W90_RS19660	COG0728	peptidoglycan biosynthetic process
G3W90_RS19665	COG0268	Binds directly to 16S ribosomal RNA
G3W90_RS19675	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G3W90_RS19680	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
G3W90_RS19685	COG3550	peptidyl-serine autophosphorylation
G3W90_RS19690	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
G3W90_RS19700	COG3483	tryptophan 2,3-dioxygenase activity
G3W90_RS19710	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G3W90_RS19720	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
G3W90_RS19720	COG1918	ferrous iron import across plasma membrane
G3W90_RS19735	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
G3W90_RS19750	COG1049	propionate catabolic process, 2-methylcitrate cycle
G3W90_RS19765	COG4106	trans-aconitate 2-methyltransferase activity
G3W90_RS19770	COG0039	L-malate dehydrogenase activity
G3W90_RS19775	COG2188	Transcriptional regulator
G3W90_RS19790	COG1053	succinate dehydrogenase
G3W90_RS19795	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
G3W90_RS19800	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
G3W90_RS19805	COG0372	Belongs to the citrate synthase family
G3W90_RS19815	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
G3W90_RS19820	COG0066	3-isopropylmalate dehydratase activity
G3W90_RS19825	COG0473	3-isopropylmalate dehydrogenase activity
G3W90_RS19830	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
G3W90_RS19840	COG0101	tRNA pseudouridine synthase activity
G3W90_RS19845	COG0135	phosphoribosylanthranilate isomerase activity
G3W90_RS19850	COG0133	tryptophan synthase activity
G3W90_RS19855	COG0159	tryptophan synthase activity
G3W90_RS19860	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
G3W90_RS19865	COG0762	integral membrane protein
G3W90_RS19875	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
G3W90_RS19880	COG0443	Heat shock 70 kDa protein
G3W90_RS19885	COG1451	nucleotide metabolic process
G3W90_RS19890	COG1472	Belongs to the glycosyl hydrolase 3 family
G3W90_RS19895	COG0736	holo-[acyl-carrier-protein] synthase activity
G3W90_RS19900	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
G3W90_RS19905	COG1381	Involved in DNA repair and RecF pathway recombination
G3W90_RS19910	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
G3W90_RS19915	COG0571	ribonuclease III activity
G3W90_RS19925	COG0681	Belongs to the peptidase S26 family
G3W90_RS19930	COG0481	GTPase activity
G3W90_RS19935	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G3W90_RS19960	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G3W90_RS19965	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G3W90_RS19970	COG1028	Short-chain dehydrogenase reductase Sdr
G3W90_RS19975	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
G3W90_RS19980	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G3W90_RS19985	COG0416	fatty acid biosynthetic process
G3W90_RS19990	COG0333	Belongs to the bacterial ribosomal protein bL32 family
G3W90_RS19995	COG1399	metal-binding, possibly nucleic acid-binding protein
G3W90_RS20000	COG0424	maF-like protein
G3W90_RS20005	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
G3W90_RS20010	COG2223	nitrite transmembrane transporter activity
G3W90_RS20035	COG1530	ribonuclease E activity
G3W90_RS20050	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G3W90_RS20070	COG0297	glycogen (starch) synthase activity
G3W90_RS20075	COG3206	protein involved in exopolysaccharide biosynthesis
G3W90_RS20075	COG0489	protein tyrosine kinase activity
G3W90_RS20105	COG0181	hydroxymethylbilane synthase activity
G3W90_RS20110	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
G3W90_RS20120	COG3459	Glycosyltransferase 36 associated
G3W90_RS20135	COG3275	phosphorelay sensor kinase activity
G3W90_RS20140	COG0165	Argininosuccinate lyase
G3W90_RS20180	COG0438	transferase activity, transferring glycosyl groups
G3W90_RS20195	COG2197	response regulator
G3W90_RS20220	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G3W90_RS20230	COG0583	DNA-binding transcription factor activity
G3W90_RS20235	COG4948	Mandelate Racemase Muconate Lactonizing
G3W90_RS20245	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
G3W90_RS20255	COG0477	Major facilitator Superfamily
G3W90_RS20265	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
G3W90_RS20295	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
G3W90_RS20295	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
G3W90_RS20310	COG3022	response to hydroperoxide
G3W90_RS20315	COG0525	valine-tRNA ligase activity
G3W90_RS20330	COG0425	Belongs to the sulfur carrier protein TusA family
G3W90_RS20335	COG2816	NAD+ diphosphatase activity
G3W90_RS20355	COG2203	Gaf domain
G3W90_RS20355	COG5001	Diguanylate cyclase
G3W90_RS20355	COG4251	negative regulation of phosphorylation
G3W90_RS20355	COG3706	GGDEF domain
G3W90_RS20365	COG5002	protein histidine kinase activity
G3W90_RS20365	COG5001	Diguanylate cyclase
G3W90_RS20365	COG3447	MASE1 domain protein
G3W90_RS20370	COG2204	response regulator
G3W90_RS20405	COG1222	aaa ATPase
G3W90_RS20510	COG0559	Belongs to the binding-protein-dependent transport system permease family
G3W90_RS20515	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
G3W90_RS20520	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
G3W90_RS20525	COG1674	ftsk spoiiie
G3W90_RS20535	COG0492	ferredoxin-NADP+ reductase activity
G3W90_RS20540	COG0227	Belongs to the bacterial ribosomal protein bL28 family
G3W90_RS20545	COG0267	Belongs to the bacterial ribosomal protein bL33 family
G3W90_RS20555	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
G3W90_RS20555	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
G3W90_RS20565	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
G3W90_RS20570	COG1960	acyl-CoA dehydrogenase activity
G3W90_RS20605	COG0196	riboflavin kinase activity
G3W90_RS20615	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
G3W90_RS20620	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
G3W90_RS20625	COG1283	sodium-dependent phosphate transmembrane transporter activity
G3W90_RS20635	COG1028	Short-chain dehydrogenase reductase Sdr
G3W90_RS20645	COG0405	Gamma-glutamyltransferase
G3W90_RS20650	COG3181	Tripartite tricarboxylate transporter family receptor
G3W90_RS20655	COG0583	DNA-binding transcription factor activity
G3W90_RS20670	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
G3W90_RS20675	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
G3W90_RS20690	COG0084	hydrolase, TatD family'
G3W90_RS20695	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G3W90_RS20700	COG0714	Associated with various cellular activities
G3W90_RS20710	COG2304	oxidoreductase activity
G3W90_RS20720	COG1959	2 iron, 2 sulfur cluster binding
G3W90_RS20735	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G3W90_RS20740	COG0038	chloride channel
G3W90_RS20755	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
G3W90_RS20760	COG1737	Transcriptional regulator
G3W90_RS20795	COG0251	oxidation-reduction process
G3W90_RS20800	COG1201	RNA secondary structure unwinding
G3W90_RS20810	COG1573	uracil-dna glycosylase
G3W90_RS20815	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G3W90_RS20825	COG3842	ATPase activity
G3W90_RS20845	COG0045	succinate-CoA ligase (ADP-forming) activity
G3W90_RS20850	COG1024	Enoyl-CoA hydratase
G3W90_RS20855	COG1024	Enoyl-CoA hydratase
G3W90_RS20865	COG1024	Enoyl-CoA hydratase
G3W90_RS20870	COG2951	lytic endotransglycosylase activity
G3W90_RS20875	COG1136	(ABC) transporter
G3W90_RS20880	COG4591	ABC-type transport system involved in lipoprotein release permease component
G3W90_RS20890	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
G3W90_RS20930	COG2198	Histidine kinase
G3W90_RS20930	COG0784	Response regulator, receiver
G3W90_RS20930	COG5002	protein histidine kinase activity
G3W90_RS20935	COG0831	urea catabolic process
G3W90_RS20945	COG0832	Belongs to the urease beta subunit family
G3W90_RS20950	COG0804	urea catabolic process
G3W90_RS20965	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
G3W90_RS20970	COG0830	nickel cation binding
G3W90_RS20975	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
G3W90_RS21010	COG1024	Enoyl-CoA hydratase
G3W90_RS21020	COG1414	Transcriptional regulator
G3W90_RS21025	COG3181	Tripartite tricarboxylate transporter family receptor
G3W90_RS21030	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G3W90_RS21055	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G3W90_RS21090	COG0402	S-adenosylhomocysteine deaminase activity
G3W90_RS21095	COG0583	DNA-binding transcription factor activity
G3W90_RS21100	COG1335	isochorismatase
G3W90_RS21105	COG1942	4-Oxalocrotonate Tautomerase
G3W90_RS21130	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
G3W90_RS21135	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3W90_RS21155	COG0523	cobalamin synthesis protein
G3W90_RS21170	COG4948	Mandelate Racemase Muconate Lactonizing
G3W90_RS21180	COG1741	Belongs to the pirin family
G3W90_RS21200	COG0583	DNA-binding transcription factor activity
G3W90_RS21205	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W90_RS21375	COG0629	single-stranded DNA binding
G3W90_RS21395	COG0635	Involved in the biosynthesis of porphyrin-containing compound
G3W90_RS21400	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
G3W90_RS21405	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
G3W90_RS21415	COG2815	serine threonine protein kinase
G3W90_RS21415	COG0515	serine threonine protein kinase
G3W90_RS21420	COG1561	YicC-like family, N-terminal region
G3W90_RS21425	COG0194	GDP metabolic process
G3W90_RS21430	COG1758	RNA polymerase activity
G3W90_RS21435	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G3W90_RS21485	COG2860	membrane
G3W90_RS21495	COG1420	regulation of RNA biosynthetic process
G3W90_RS21500	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
G3W90_RS21565	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
G3W90_RS21570	COG0497	DNA recombination
G3W90_RS21575	COG1660	Displays ATPase and GTPase activities
G3W90_RS21580	COG1194	a g-specific adenine glycosylase
G3W90_RS21585	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
G3W90_RS21590	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
G3W90_RS21600	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
G3W90_RS21605	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
G3W90_RS21615	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
G3W90_RS21620	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
G3W90_RS21625	COG0193	aminoacyl-tRNA hydrolase activity
G3W90_RS21635	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
G3W90_RS21645	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G3W90_RS21650	COG0444	Belongs to the ABC transporter superfamily
G3W90_RS21655	COG4608	Belongs to the ABC transporter superfamily
G3W90_RS21660	COG0747	negative chemotaxis
G3W90_RS21665	COG0154	amidase activity
G3W90_RS21675	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
G3W90_RS21680	COG0673	inositol 2-dehydrogenase activity
G3W90_RS21690	COG0583	DNA-binding transcription factor activity
G3W90_RS21705	COG1473	amidohydrolase
G3W90_RS21710	COG0747	negative chemotaxis
G3W90_RS21715	COG0601	transmembrane transport
G3W90_RS21725	COG0444	Belongs to the ABC transporter superfamily
G3W90_RS21735	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
G3W90_RS21765	COG1957	nucleoside hydrolase
G3W90_RS21770	COG0406	alpha-ribazole phosphatase activity
G3W90_RS21775	COG2267	carboxylic ester hydrolase activity
G3W90_RS21780	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
G3W90_RS21785	COG1984	allophanate hydrolase subunit 2
G3W90_RS21790	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
G3W90_RS21795	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
G3W90_RS21800	COG0742	ribosomal rna small subunit methyltransferase
G3W90_RS21805	COG0612	Peptidase, M16
G3W90_RS21810	COG0612	Peptidase, M16
G3W90_RS21830	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
G3W90_RS21835	COG1999	signal sequence binding
G3W90_RS21840	COG0109	protoheme IX farnesyltransferase activity
G3W90_RS21870	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
G3W90_RS21875	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
G3W90_RS21880	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
G3W90_RS21890	COG2226	methyltransferase
G3W90_RS21895	COG1040	competence protein
G3W90_RS21900	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
G3W90_RS21915	COG0489	protein tyrosine kinase activity
G3W90_RS21920	COG2249	NAD(P)H dehydrogenase (quinone) activity
G3W90_RS21940	COG1733	regulation of RNA biosynthetic process
G3W90_RS21950	COG1024	Enoyl-CoA hydratase
G3W90_RS21990	COG1960	acyl-CoA dehydrogenase activity
G3W90_RS22040	COG1733	regulation of RNA biosynthetic process
G3W90_RS22045	COG1028	Short-chain dehydrogenase reductase Sdr
G3W90_RS22085	COG3485	protocatechuate 3,4-dioxygenase
G3W90_RS22110	COG0183	Belongs to the thiolase family
G3W90_RS22115	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
G3W90_RS22125	COG1414	Transcriptional regulator
G3W90_RS22150	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
G3W90_RS22200	COG1137	ATPase activity
G3W90_RS22210	COG1012	belongs to the aldehyde dehydrogenase family
G3W90_RS22225	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G3W90_RS22240	COG0583	DNA-binding transcription factor activity
G3W90_RS22255	COG0583	DNA-binding transcription factor activity
G3W90_RS22260	COG3485	protocatechuate 3,4-dioxygenase
G3W90_RS22265	COG3485	protocatechuate 3,4-dioxygenase
G3W90_RS22275	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G3W90_RS22575	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
G3W90_RS22595	COG0583	DNA-binding transcription factor activity
G3W90_RS22600	COG1473	amidohydrolase
G3W90_RS22615	COG3181	Tripartite tricarboxylate transporter family receptor
G3W90_RS22625	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W90_RS22630	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W90_RS22675	COG1566	PFAM secretion protein HlyD family protein
G3W90_RS22685	COG0477	Major facilitator Superfamily
G3W90_RS22700	COG0540	Belongs to the ATCase OTCase family
G3W90_RS22705	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
G3W90_RS22710	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
G3W90_RS22715	COG1678	Uncharacterized ACR, COG1678
G3W90_RS22720	COG0415	Belongs to the DNA photolyase family
G3W90_RS22725	COG0643	Histidine kinase
G3W90_RS22725	COG2198	Histidine kinase
G3W90_RS22730	COG0840	transmembrane signaling receptor activity
G3W90_RS22750	COG1773	rubredoxin
G3W90_RS22760	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
G3W90_RS22770	COG0138	bifunctional purine biosynthesis protein purh
G3W90_RS22780	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
G3W90_RS22785	COG1238	metal cluster binding
G3W90_RS22795	COG2080	2 iron, 2 sulfur cluster binding
G3W90_RS22800	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
G3W90_RS22805	COG1529	Aldehyde oxidase and xanthine dehydrogenase
G3W90_RS22810	COG1529	Aldehyde oxidase and xanthine dehydrogenase
G3W90_RS22815	COG0012	GTP binding
G3W90_RS22820	COG0633	Ferredoxin
G3W90_RS22820	COG3217	Mosc domain protein beta barrel domain protein
G3W90_RS22825	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G3W90_RS22840	COG1024	Enoyl-CoA hydratase
G3W90_RS22870	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W90_RS22875	COG1028	Short-chain dehydrogenase reductase Sdr
G3W90_RS22895	COG1024	Enoyl-CoA hydratase
G3W90_RS22910	COG1960	acyl-CoA dehydrogenase activity
G3W90_RS22915	COG1960	acyl-CoA dehydrogenase activity
G3W90_RS22920	COG0318	PFAM AMP-dependent synthetase and ligase
G3W90_RS22930	COG2084	Dehydrogenase
G3W90_RS22965	COG1028	Short-chain dehydrogenase reductase Sdr
G3W90_RS22970	COG1024	Enoyl-CoA hydratase
G3W90_RS22975	COG1902	pentaerythritol trinitrate reductase activity
G3W90_RS22975	COG0446	pyridine nucleotide-disulphide oxidoreductase
G3W90_RS22980	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
G3W90_RS22985	COG1028	Short-chain dehydrogenase reductase Sdr
G3W90_RS22995	COG1960	acyl-CoA dehydrogenase activity
G3W90_RS23000	COG0583	DNA-binding transcription factor activity
G3W90_RS23005	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W90_RS23010	COG1024	Enoyl-CoA hydratase
G3W90_RS23015	COG1960	acyl-CoA dehydrogenase activity
G3W90_RS23020	COG1960	acyl-CoA dehydrogenase activity
G3W90_RS23045	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G3W90_RS23065	COG0559	Belongs to the binding-protein-dependent transport system permease family
G3W90_RS23075	COG1028	Short-chain dehydrogenase reductase Sdr
G3W90_RS23115	COG2255	four-way junction helicase activity
G3W90_RS23125	COG0632	four-way junction helicase activity
G3W90_RS23130	COG1702	phosphate starvation-inducible protein PhoH
G3W90_RS23135	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
G3W90_RS23140	COG1490	D-aminoacyl-tRNA deacylase activity
G3W90_RS23145	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
G3W90_RS23150	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
G3W90_RS23155	COG0739	heme binding
G3W90_RS23160	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
G3W90_RS23165	COG2814	Major facilitator Superfamily
G3W90_RS23170	COG0316	Belongs to the HesB IscA family
G3W90_RS23175	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
G3W90_RS23180	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
G3W90_RS23185	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
G3W90_RS23190	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
G3W90_RS23205	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
G3W90_RS23210	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
G3W90_RS23230	COG1309	transcriptional regulator
G3W90_RS23255	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3W90_RS23285	COG1309	transcriptional regulator
G3W90_RS23290	COG1024	Enoyl-CoA hydratase
G3W90_RS23300	COG0318	PFAM AMP-dependent synthetase and ligase
G3W90_RS23315	COG1176	ABC-type spermidine putrescine transport system, permease component I
G3W90_RS23320	COG3842	ATPase activity
G3W90_RS23330	COG2175	clavaminate synthase activity
G3W90_RS23350	COG0477	Major facilitator Superfamily
G3W90_RS23375	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G3W90_RS23390	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
G3W90_RS23400	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G3W90_RS23405	COG0318	PFAM AMP-dependent synthetase and ligase
G3W90_RS23410	COG1960	acyl-CoA dehydrogenase activity
G3W90_RS23425	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G3W90_RS23430	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
G3W90_RS23445	COG3012	SEC-C Motif Domain Protein
G3W90_RS23450	COG1960	acyl-CoA dehydrogenase activity
G3W90_RS23455	COG0183	Belongs to the thiolase family
G3W90_RS23460	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
G3W90_RS23465	COG0288	reversible hydration of carbon dioxide
G3W90_RS23470	COG0789	Transcriptional regulator
G3W90_RS23485	COG0564	pseudouridine synthase activity
G3W90_RS23490	COG2197	response regulator
G3W90_RS23495	COG2205	protein histidine kinase activity
G3W90_RS23515	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
G3W90_RS23520	COG0751	glycine-tRNA ligase activity
G3W90_RS23525	COG0752	glycyl-tRNA synthetase alpha subunit
G3W90_RS23535	COG0815	Transfers the fatty acyl group on membrane lipoproteins
G3W90_RS23540	COG4535	Mg2 and Co2 transporter CorC
G3W90_RS23550	COG1522	sequence-specific DNA binding
G3W90_RS23565	COG3186	Phenylalanine-4-hydroxylase
G3W90_RS23570	COG0318	PFAM AMP-dependent synthetase and ligase
G3W90_RS23610	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G3W90_RS23615	COG2188	Transcriptional regulator
G3W90_RS23620	COG0697	spore germination
G3W90_RS23625	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G3W90_RS23635	COG0384	phenazine biosynthesis protein PhzF
G3W90_RS23645	COG1280	lysine exporter protein (LysE YggA)
G3W90_RS23655	COG3468	outer membrane autotransporter barrel domain protein
G3W90_RS23655	COG3468	outer membrane autotransporter barrel domain protein
G3W90_RS23680	COG1881	PFAM PEBP family protein
G3W90_RS23695	COG0402	S-adenosylhomocysteine deaminase activity
G3W90_RS23710	COG1609	Transcriptional regulator
G3W90_RS23720	COG4232	protein-disulfide reductase activity
G3W90_RS23725	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G3W90_RS23730	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
G3W90_RS23735	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
G3W90_RS23750	COG0679	Auxin Efflux Carrier
G3W90_RS23755	COG0210	DNA helicase
G3W90_RS23770	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
G3W90_RS23775	COG1012	belongs to the aldehyde dehydrogenase family
G3W90_RS23790	COG1172	Belongs to the binding-protein-dependent transport system permease family
G3W90_RS23795	COG1129	ABC transporter
G3W90_RS23805	COG1028	Short-chain dehydrogenase reductase Sdr
G3W90_RS23810	COG0028	Belongs to the TPP enzyme family
G3W90_RS23815	COG1902	pentaerythritol trinitrate reductase activity
G3W90_RS23820	COG3347	Dehydrogenase
G3W90_RS23820	COG1028	Short-chain dehydrogenase reductase Sdr
G3W90_RS23825	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
G3W90_RS23850	COG1028	Short-chain dehydrogenase reductase Sdr
G3W90_RS23865	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G3W90_RS23885	COG0402	S-adenosylhomocysteine deaminase activity
G3W90_RS23890	COG3181	Tripartite tricarboxylate transporter family receptor
G3W90_RS23905	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3W90_RS23910	COG1116	anion transmembrane transporter activity
G3W90_RS23910	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G3W90_RS23920	COG3181	Tripartite tricarboxylate transporter family receptor
G3W90_RS23940	COG3246	L-lysine catabolic process to acetate
G3W90_RS23945	COG2175	clavaminate synthase activity
G3W90_RS23955	COG2175	clavaminate synthase activity
G3W90_RS23980	COG3181	Tripartite tricarboxylate transporter family receptor
G3W90_RS23985	COG3246	L-lysine catabolic process to acetate
G3W90_RS23995	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3W90_RS24000	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
G3W90_RS24025	COG0439	Biotin carboxylase
G3W90_RS24035	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W90_RS24040	COG2186	Transcriptional regulator
G3W90_RS24045	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W90_RS24050	COG0511	ligase activity, forming carbon-carbon bonds
G3W90_RS24055	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W90_RS24060	COG0431	NADPH-dependent FMN reductase
G3W90_RS24090	COG1454	alcohol dehydrogenase
G3W90_RS24090	COG1012	belongs to the aldehyde dehydrogenase family
G3W90_RS24095	COG2175	clavaminate synthase activity
G3W90_RS24120	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3W90_RS24135	COG1028	Short-chain dehydrogenase reductase Sdr
G3W90_RS24150	COG1960	acyl-CoA dehydrogenase activity
G3W90_RS24160	COG1024	Enoyl-CoA hydratase
G3W90_RS24170	COG0583	DNA-binding transcription factor activity
G3W90_RS24175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G3W90_RS24180	COG3181	Tripartite tricarboxylate transporter family receptor
G3W90_RS24185	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G3W90_RS24190	COG0426	domain, Protein
G3W90_RS24190	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G3W90_RS24195	COG1028	Short-chain dehydrogenase reductase Sdr
G3W90_RS24325	COG3451	type IV secretory pathway VirB4
G3W90_RS24340	COG4962	Type ii secretion system protein e
G3W90_RS24355	COG0583	DNA-binding transcription factor activity
G3W90_RS24365	COG1028	Short-chain dehydrogenase reductase Sdr
G3W90_RS24375	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
G3W90_RS24380	COG3181	Tripartite tricarboxylate transporter family receptor
G3W90_RS24385	COG0445	tRNA wobble uridine modification
G3W90_RS24395	COG1802	Transcriptional regulator
G3W90_RS24410	COG1028	Short-chain dehydrogenase reductase Sdr
G3W90_RS24420	COG4670	ketone body catabolic process
G3W90_RS24440	COG4959	Type IV secretory pathway protease TraF
G3W90_RS24455	COG1192	Involved in chromosome partitioning
G3W90_RS24480	COG1396	sequence-specific DNA binding
G3W90_RS24495	COG5489	Protein of unknown function (DUF736)
G3W90_RS24505	COG1475	DNA binding
G3W90_RS24540	COG0582	viral genome integration into host DNA
G3W90_RS24550	COG2204	response regulator
G3W90_RS24555	COG5000	phosphorelay sensor kinase activity
G3W90_RS24575	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
G3W90_RS24580	COG0085	RNA polymerase activity
G3W90_RS24585	COG0222	ribosome binding
G3W90_RS24590	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
G3W90_RS24595	COG0081	regulation of translation
G3W90_RS24600	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
G3W90_RS24610	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
G3W90_RS24620	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
G3W90_RS24640	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
G3W90_RS24645	COG0134	indole-3-glycerol-phosphate synthase activity
G3W90_RS24650	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
G3W90_RS24655	COG1280	lysine exporter protein (LysE YggA)
G3W90_RS24685	COG0546	phosphoglycolate phosphatase activity
G3W90_RS24805	COG3501	Rhs element vgr protein
G3W90_RS24860	COG0515	serine threonine protein kinase
G3W90_RS24895	COG0154	amidase activity
G3W90_RS24905	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
G3W90_RS24920	COG4251	negative regulation of phosphorylation
G3W90_RS24995	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
G3W90_RS25020	COG1473	amidohydrolase
G3W90_RS25050	COG3265	gluconokinase activity
G3W90_RS25075	COG0674	pyruvate-flavodoxin oxidoreductase activity
G3W90_RS25075	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
G3W90_RS25090	COG2967	ApaG domain
G3W90_RS25100	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
G3W90_RS25125	COG0583	DNA-binding transcription factor activity
G3W90_RS25140	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G3W90_RS25145	COG2205	protein histidine kinase activity
G3W90_RS25145	COG2198	Histidine kinase
G3W90_RS25145	COG0784	Response regulator, receiver
G3W90_RS25150	COG2197	response regulator
G3W90_RS25165	COG3181	Tripartite tricarboxylate transporter family receptor
G3W90_RS25180	COG2226	methyltransferase
G3W90_RS25185	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G3W90_RS25190	COG4948	Mandelate Racemase Muconate Lactonizing
G3W90_RS25195	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
G3W90_RS25205	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G3W90_RS25220	COG0583	DNA-binding transcription factor activity
G3W90_RS25225	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
G3W90_RS25245	COG3181	Tripartite tricarboxylate transporter family receptor
G3W90_RS25265	COG0653	protein targeting
G3W90_RS25270	COG0069	glutamate synthase activity
G3W90_RS25280	COG0783	Belongs to the Dps family
G3W90_RS25285	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G3W90_RS25300	COG2197	response regulator
G3W90_RS25305	COG4585	Histidine kinase
G3W90_RS25315	COG0784	Response regulator, receiver
G3W90_RS25315	COG2205	protein histidine kinase activity
G3W90_RS25320	COG3038	cytochrome b561
G3W90_RS25335	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G3W90_RS25340	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
G3W90_RS25345	COG1137	ATPase activity
G3W90_RS25350	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
G3W90_RS25355	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
G3W90_RS25365	COG0018	arginyl-trna synthetase
G3W90_RS25395	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W90_RS25400	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G3W90_RS25405	COG1414	Transcriptional regulator
G3W90_RS25415	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
G3W90_RS25430	COG2205	protein histidine kinase activity
G3W90_RS25430	COG0784	Response regulator, receiver
G3W90_RS25465	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
G3W90_RS25470	COG0583	DNA-binding transcription factor activity
G3W90_RS25480	COG0205	6-phosphofructokinase activity
G3W90_RS25495	COG2814	Major facilitator Superfamily
G3W90_RS25500	COG0121	glutamine amidotransferase
G3W90_RS25505	COG0189	ligase activity
G3W90_RS25510	COG3135	benzoate transporter
G3W90_RS25515	COG3158	transport of potassium into the cell
G3W90_RS25525	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
G3W90_RS25535	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
G3W90_RS25540	COG0495	leucyl-tRNA aminoacylation
G3W90_RS25545	COG1523	belongs to the glycosyl hydrolase 13 family
G3W90_RS25550	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
G3W90_RS25555	COG0297	glycogen (starch) synthase activity
G3W90_RS25560	COG0058	SHG alpha-glucan phosphorylase activity
G3W90_RS25570	COG1921	L-seryl-tRNASec selenium transferase activity
G3W90_RS25580	COG0492	ferredoxin-NADP+ reductase activity
G3W90_RS25605	COG1028	Short-chain dehydrogenase reductase Sdr
G3W90_RS25615	COG1305	Transglutaminase-like
G3W90_RS25620	COG0583	DNA-binding transcription factor activity
G3W90_RS25635	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
G3W90_RS25640	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G3W90_RS25645	COG0735	belongs to the Fur family
G3W90_RS25650	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
G3W90_RS25660	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
G3W90_RS25665	COG0210	DNA helicase
G3W90_RS25670	COG0598	Magnesium transport protein CorA
G3W90_RS25695	COG4638	Rieske (2fe-2S)
G3W90_RS25700	COG0179	Fumarylacetoacetate (FAA) hydrolase
G3W90_RS25710	COG0028	Belongs to the TPP enzyme family
G3W90_RS25720	COG0747	negative chemotaxis
G3W90_RS25725	COG4608	Belongs to the ABC transporter superfamily
G3W90_RS25730	COG0444	Belongs to the ABC transporter superfamily
G3W90_RS25735	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G3W90_RS25740	COG0601	transmembrane transport
G3W90_RS25745	COG0318	PFAM AMP-dependent synthetase and ligase
G3W90_RS25765	COG0745	RESPONSE REGULATOR receiver
G3W90_RS25780	COG0482	sulfurtransferase activity
G3W90_RS25785	COG0318	PFAM AMP-dependent synthetase and ligase
G3W90_RS25795	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G3W90_RS25805	COG3181	Tripartite tricarboxylate transporter family receptor
G3W90_RS25810	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
G3W90_RS25815	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G3W90_RS25820	COG2721	sulfolactate sulfo-lyase activity
G3W90_RS25825	COG2721	sulfolactate sulfo-lyase activity
G3W90_RS25845	COG0629	single-stranded DNA binding
G3W90_RS25890	COG0745	RESPONSE REGULATOR receiver
G3W90_RS25900	COG3852	Histidine kinase
G3W90_RS25925	COG1902	pentaerythritol trinitrate reductase activity
G3W90_RS25975	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3W90_RS25985	COG0596	Alpha beta hydrolase
G3W90_RS25995	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G3W90_RS26005	COG0583	DNA-binding transcription factor activity
G3W90_RS26025	COG0583	DNA-binding transcription factor activity
G3W90_RS26045	COG1028	Short-chain dehydrogenase reductase Sdr
G3W90_RS26055	COG5002	protein histidine kinase activity
G3W90_RS26060	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
G3W90_RS26070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G3W90_RS26075	COG1946	Acyl-CoA thioesterase
G3W90_RS26080	COG0446	pyridine nucleotide-disulphide oxidoreductase
G3W90_RS26085	COG3181	Tripartite tricarboxylate transporter family receptor
G3W90_RS26090	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G3W90_RS26105	COG0583	DNA-binding transcription factor activity
G3W90_RS26115	COG0179	Fumarylacetoacetate (FAA) hydrolase
G3W90_RS26120	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
G3W90_RS26155	COG0284	orotidine-5'-phosphate decarboxylase activity
G3W90_RS26175	COG2027	D-alanyl-D-alanine carboxypeptidase
G3W90_RS26185	COG0009	L-threonylcarbamoyladenylate synthase
G3W90_RS26190	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
G3W90_RS26195	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
G3W90_RS26200	COG3118	belongs to the thioredoxin family
G3W90_RS26210	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
G3W90_RS26225	COG0469	pyruvate kinase activity
G3W90_RS26230	COG0126	phosphoglycerate kinase activity
G3W90_RS26245	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
G3W90_RS26255	COG0242	peptide deformylase activity
G3W90_RS26265	COG0758	DNA mediated transformation
G3W90_RS26270	COG2922	Belongs to the Smg family
G3W90_RS26280	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G3W90_RS26285	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G3W90_RS26290	COG1862	Preprotein translocase
G3W90_RS26295	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
G3W90_RS26300	COG0439	Biotin carboxylase
G3W90_RS26305	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G3W90_RS26330	COG0318	PFAM AMP-dependent synthetase and ligase
G3W90_RS26340	COG1960	acyl-CoA dehydrogenase activity
G3W90_RS26350	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G3W90_RS26365	COG1024	Enoyl-CoA hydratase
G3W90_RS26365	COG1250	3-hydroxyacyl-CoA dehydrogenase
G3W90_RS26390	COG1024	Enoyl-CoA hydratase
G3W90_RS26395	COG2909	trisaccharide binding
G3W90_RS26405	COG4948	Mandelate Racemase Muconate Lactonizing
G3W90_RS26410	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G3W90_RS26420	COG1129	ABC transporter
G3W90_RS26435	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G3W90_RS26445	COG0183	Belongs to the thiolase family
G3W90_RS26450	COG2030	dehydratase
G3W90_RS26455	COG1024	Enoyl-CoA hydratase
G3W90_RS26460	COG1024	Enoyl-CoA hydratase
G3W90_RS26460	COG1250	3-hydroxyacyl-CoA dehydrogenase
G3W90_RS26465	COG1024	Enoyl-CoA hydratase
G3W90_RS26470	COG1960	acyl-CoA dehydrogenase activity
G3W90_RS26475	COG2368	4-hydroxyphenylacetate
G3W90_RS26535	COG1028	Short-chain dehydrogenase reductase Sdr
G3W90_RS26545	COG1522	sequence-specific DNA binding
G3W90_RS26550	COG0625	glutathione transferase activity
G3W90_RS26565	COG5001	Diguanylate cyclase
G3W90_RS26565	COG5002	protein histidine kinase activity
G3W90_RS26590	COG0586	Pfam SNARE associated Golgi protein
G3W90_RS26610	COG3622	Belongs to the hyi family
G3W90_RS26615	COG3395	kinase activity
G3W90_RS26620	COG2084	Dehydrogenase
G3W90_RS26625	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
G3W90_RS26630	COG1522	sequence-specific DNA binding
G3W90_RS26650	COG4566	intracellular signal transduction
G3W90_RS26670	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
G3W90_RS26690	COG0625	glutathione transferase activity
G3W90_RS26715	COG0861	Integral membrane protein TerC family
G3W90_RS26725	COG1950	PFAM Membrane protein of
G3W90_RS26735	COG4783	chaperone-mediated protein folding
G3W90_RS26740	COG0315	cyclic pyranopterin monophosphate synthase activity
G3W90_RS26785	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G3W90_RS26790	COG0438	transferase activity, transferring glycosyl groups
G3W90_RS26795	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
G3W90_RS26825	COG3307	-O-antigen
G3W90_RS26830	COG4969	Belongs to the N-Me-Phe pilin family
G3W90_RS26850	COG0861	Integral membrane protein TerC family
G3W90_RS26855	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
G3W90_RS26860	COG0045	succinate-CoA ligase (ADP-forming) activity
G3W90_RS26865	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
G3W90_RS26870	COG2137	regulation of response to DNA damage stimulus
G3W90_RS26875	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
G3W90_RS26890	COG0642	Histidine kinase
G3W90_RS26900	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
G3W90_RS26900	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
G3W90_RS26910	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
G3W90_RS26910	COG0551	DNA topoisomerase type I activity
G3W90_RS26915	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
G3W90_RS26925	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G3W90_RS26935	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
G3W90_RS26940	COG0513	Belongs to the DEAD box helicase family
G3W90_RS26960	COG1473	amidohydrolase
G3W90_RS26970	COG0129	dihydroxy-acid dehydratase activity
G3W90_RS26975	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G3W90_RS26985	COG3842	ATPase activity
G3W90_RS27000	COG3833	ABC-type maltose transport systems, permease component
G3W90_RS27005	COG2982	Protein involved in outer membrane biogenesis
G3W90_RS27015	COG1047	Peptidyl-prolyl cis-trans
G3W90_RS27025	COG0765	amino acid transport
G3W90_RS27030	COG0765	amino acid transport
G3W90_RS27085	COG2814	Major facilitator Superfamily
G3W90_RS27090	COG0583	DNA-binding transcription factor activity
G3W90_RS27095	COG0165	Argininosuccinate lyase
G3W90_RS27115	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G3W90_RS27120	COG0667	Aldo Keto reductase
G3W90_RS27130	COG1522	sequence-specific DNA binding
G3W90_RS27135	COG2423	ornithine cyclodeaminase activity
G3W90_RS27145	COG2094	Belongs to the DNA glycosylase MPG family
G3W90_RS27195	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
G3W90_RS27225	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
G3W90_RS27230	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
G3W90_RS27235	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
G3W90_RS27250	COG0006	proline dipeptidase activity
G3W90_RS27265	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
G3W90_RS27285	COG0281	malic enzyme
G3W90_RS27285	COG0280	phosphate acetyltransferase
G3W90_RS27305	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
G3W90_RS27310	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G3W90_RS27315	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
G3W90_RS27325	COG1385	rRNA (uridine-N3-)-methyltransferase activity
G3W90_RS27335	COG3753	Protein conserved in bacteria
G3W90_RS27340	COG2814	Major facilitator Superfamily
G3W90_RS27350	COG2267	carboxylic ester hydrolase activity
G3W90_RS27370	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G3W90_RS27375	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G3W90_RS27380	COG0724	RNA recognition motif
G3W90_RS27385	COG0300	oxidoreductase activity
G3W90_RS27395	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
G3W90_RS27415	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
G3W90_RS27415	COG2066	Belongs to the glutaminase family
G3W90_RS27420	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
G3W90_RS27425	COG0706	membrane insertase activity
G3W90_RS27430	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
G3W90_RS27435	COG0594	ribonuclease P activity
G3W90_RS27440	COG0230	Belongs to the bacterial ribosomal protein bL34 family
G3W90_RS27445	COG1192	Involved in chromosome partitioning
G3W90_RS27460	COG1199	ATP-dependent helicase activity
G3W90_RS27625	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
G3W90_RS27680	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
G3W90_RS27705	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
G3W90_RS27710	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
G3W90_RS27750	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
G3W90_RS27755	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
G3W90_RS28025	COG4682	membrane
G3W90_RS28030	COG0433	COG0433 Predicted ATPase
G3W90_RS28130	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
G3W90_RS28130	COG0551	DNA topoisomerase type I activity
G3W90_RS28185	COG4974	Belongs to the 'phage' integrase family
G3W90_RS28365	COG0545	Peptidyl-prolyl cis-trans isomerase
G3W90_RS28375	COG2954	triphosphatase activity
G3W90_RS28455	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
G3W90_RS28490	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
G3W90_RS28550	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
G3W90_RS28565	COG3011	Protein conserved in bacteria
G3W90_RS28665	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
G3W90_RS28780	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
G3W90_RS28790	COG0215	cysteine-tRNA ligase activity
G3W90_RS29015	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G3W90_RS29095	COG1074	ATP-dependent DNA helicase activity
G3W90_RS29125	COG4286	Uncharacterised protein family (UPF0160)
G3W90_RS29140	COG2433	Pfam Transposase IS66
G3W90_RS29160	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G3W90_RS29160	COG0519	Catalyzes the synthesis of GMP from XMP
G3W90_RS29180	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G3W90_RS29180	COG0519	Catalyzes the synthesis of GMP from XMP
G3W90_RS29225	COG3181	Tripartite tricarboxylate transporter family receptor
G3W90_RS29255	COG1454	alcohol dehydrogenase
G3W90_RS29270	COG3181	Tripartite tricarboxylate transporter family receptor
G3W90_RS29275	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G3W90_RS29305	COG1484	DNA-dependent DNA replication
G3W90_RS29330	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
G3W90_RS29525	COG4650	regulator
G3W90_RS29595	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
G3W90_RS29620	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
G3W90_RS29870	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
G3W90_RS29895	COG4637	Psort location Cytoplasmic, score
G3W90_RS29930	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
G3W90_RS29935	COG1518	maintenance of DNA repeat elements
G3W90_RS29940	COG1203	CRISPR-associated helicase, Cas3
G3W90_RS29950	COG0587	DNA-directed DNA polymerase activity
G3W90_RS30020	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
G3W90_RS30060	COG0084	hydrolase, TatD family'
G3W90_RS30335	COG2268	Band 7 protein
G3W90_RS30360	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G3W90_RS30390	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G3W90_RS30400	COG0628	permease
G3W90_RS30410	COG1129	ABC transporter
G3W90_RS30445	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
G3W90_RS30510	COG0675	Transposase, IS605 OrfB family
G3W90_RS30560	COG1222	aaa ATPase
G3W90_RS30565	COG1199	ATP-dependent helicase activity
G3W90_RS30610	COG0557	exoribonuclease II activity
G3W90_RS30705	COG0617	tRNA 3'-terminal CCA addition
G3W90_RS30715	COG1051	belongs to the nudix hydrolase family
G3W90_RS30715	COG1056	cytidyltransferase-related domain
G3W90_RS30735	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
G3W90_RS30735	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G3W90_RS30780	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
G3W90_RS30850	COG2189	Belongs to the N(4) N(6)-methyltransferase family
G3W90_RS30895	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G3W90_RS30900	COG1484	DNA-dependent DNA replication
G3W90_RS30920	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
G3W90_RS30950	COG0494	nUDIX hydrolase
G3W90_RS31030	COG4974	Belongs to the 'phage' integrase family
G3W90_RS31180	COG0328	RNA-DNA hybrid ribonuclease activity
G3W90_RS31230	COG0629	single-stranded DNA binding
G3W90_RS31265	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
G3W90_RS31300	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G3W90_RS31300	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G3W90_RS31435	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
G3W90_RS31440	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
G3W90_RS31485	COG0840	transmembrane signaling receptor activity
G3W90_RS31490	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
G3W90_RS31555	COG0582	viral genome integration into host DNA
G3W90_RS31680	COG0210	DNA helicase
G3W90_RS31725	COG0653	protein targeting
G3W90_RS31760	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
G3W90_RS31770	COG1484	DNA-dependent DNA replication
G3W90_RS31780	COG0187	DNA topoisomerase II activity
G3W90_RS31785	COG0739	heme binding
G3W90_RS31785	COG0741	lytic transglycosylase activity
G3W90_RS31785	COG1196	nuclear chromosome segregation
G3W90_RS31790	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
G3W90_RS31820	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
G3W90_RS31840	COG1192	Involved in chromosome partitioning
G3W90_RS31865	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
G3W90_RS31875	COG0583	DNA-binding transcription factor activity
G3W90_RS31975	COG1960	acyl-CoA dehydrogenase activity
G3W90_RS31990	COG0318	PFAM AMP-dependent synthetase and ligase
G3W90_RS31995	COG4608	Belongs to the ABC transporter superfamily
G3W90_RS32000	COG2207	Transcriptional regulator
G3W90_RS32005	COG2175	clavaminate synthase activity
G3W90_RS32020	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G3W90_RS32035	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G3W90_RS32060	COG4566	intracellular signal transduction
G3W90_RS32075	COG0318	PFAM AMP-dependent synthetase and ligase
G3W90_RS32080	COG1024	Enoyl-CoA hydratase
G3W90_RS32095	COG0183	Belongs to the thiolase family
G3W90_RS32120	COG1024	Enoyl-CoA hydratase
G3W90_RS32165	COG1309	transcriptional regulator
G3W90_RS32170	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
G3W90_RS32185	COG1024	Enoyl-CoA hydratase
G3W90_RS32200	COG1028	Short-chain dehydrogenase reductase Sdr
G3W90_RS32205	COG0318	PFAM AMP-dependent synthetase and ligase
G3W90_RS32210	COG1960	acyl-CoA dehydrogenase activity
G3W90_RS32245	COG2072	flavoprotein involved in K transport
G3W90_RS32290	COG1028	Short-chain dehydrogenase reductase Sdr
G3W90_RS32305	COG4566	intracellular signal transduction
G3W90_RS32320	COG2831	hemolysin activation secretion protein
G3W90_RS32345	COG3181	Tripartite tricarboxylate transporter family receptor
G3W90_RS32355	COG4948	Mandelate Racemase Muconate Lactonizing
G3W90_RS32375	COG3842	ATPase activity
G3W90_RS32400	COG3386	PFAM SMP-30 Gluconolaconase
G3W90_RS32420	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
G3W90_RS32430	COG2197	response regulator
G3W90_RS32435	COG4585	Histidine kinase
G3W90_RS32440	COG2205	protein histidine kinase activity
G3W90_RS32445	COG0667	Aldo Keto reductase
G3W90_RS32455	COG0765	amino acid transport
G3W90_RS32460	COG0765	amino acid transport
G3W90_RS32465	COG1126	abc transporter atp-binding protein
G3W90_RS32475	COG1522	sequence-specific DNA binding
G3W90_RS32480	COG3842	ATPase activity
G3W90_RS32495	COG1176	ABC-type spermidine putrescine transport system, permease component I
G3W90_RS32500	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
G3W90_RS32500	COG0778	Nitroreductase
G3W90_RS32505	COG1920	GTP binding
G3W90_RS32510	COG0391	Required for morphogenesis under gluconeogenic growth conditions
G3W90_RS32515	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
G3W90_RS32520	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
G3W90_RS32525	COG0251	oxidation-reduction process
G3W90_RS32535	COG0523	cobalamin synthesis protein
G3W90_RS32555	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G3W90_RS32565	COG1414	Transcriptional regulator
G3W90_RS32590	COG3268	Saccharopine dehydrogenase
G3W90_RS32595	COG0318	PFAM AMP-dependent synthetase and ligase
G3W90_RS32605	COG0183	Belongs to the thiolase family
G3W90_RS32610	COG0604	alcohol dehydrogenase
G3W90_RS32635	COG1024	Enoyl-CoA hydratase
G3W90_RS32640	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W90_RS32645	COG2814	Major facilitator Superfamily
G3W90_RS32665	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
G3W90_RS32675	COG0583	DNA-binding transcription factor activity
G3W90_RS32695	COG1028	Short-chain dehydrogenase reductase Sdr
G3W90_RS32705	COG3181	Tripartite tricarboxylate transporter family receptor
G3W90_RS32710	COG1053	succinate dehydrogenase
G3W90_RS32725	COG3181	Tripartite tricarboxylate transporter family receptor
G3W90_RS32735	COG0165	Argininosuccinate lyase
G3W90_RS32740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G3W90_RS32750	COG0765	amino acid transport
G3W90_RS32755	COG0010	Belongs to the arginase family
G3W90_RS32765	COG0579	oxidoreductase
G3W90_RS32785	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G3W90_RS32805	COG1335	isochorismatase
G3W90_RS32825	COG0791	NLP P60 protein
G3W90_RS32835	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
G3W90_RS32865	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G3W90_RS32870	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G3W90_RS32895	COG3386	PFAM SMP-30 Gluconolaconase
G3W90_RS32900	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
G3W90_RS32910	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G3W90_RS32920	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W90_RS32945	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W90_RS32955	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
G3W90_RS32960	COG0439	Biotin carboxylase
G3W90_RS32970	COG3181	Tripartite tricarboxylate transporter family receptor
G3W90_RS32995	COG1172	Belongs to the binding-protein-dependent transport system permease family
G3W90_RS33010	COG0066	3-isopropylmalate dehydratase activity
G3W90_RS33015	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
G3W90_RS33020	COG0277	FAD linked oxidase domain protein
G3W90_RS33020	COG0247	lactate metabolic process
G3W90_RS33040	COG0028	Belongs to the TPP enzyme family
G3W90_RS33095	COG0625	glutathione transferase activity
G3W90_RS33140	COG3181	Tripartite tricarboxylate transporter family receptor
G3W90_RS33145	COG0583	DNA-binding transcription factor activity
G3W90_RS33150	COG0604	alcohol dehydrogenase
G3W90_RS33160	COG1024	Enoyl-CoA hydratase
G3W90_RS33170	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3W90_RS33210	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
G3W90_RS33215	COG1414	Transcriptional regulator
G3W90_RS33235	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G3W90_RS33240	COG0586	Pfam SNARE associated Golgi protein
G3W90_RS33250	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
G3W90_RS33250	COG1672	PFAM Archaeal ATPase
G3W90_RS33270	COG1028	Short-chain dehydrogenase reductase Sdr
G3W90_RS33275	COG1028	Short-chain dehydrogenase reductase Sdr
G3W90_RS33290	COG1176	ABC-type spermidine putrescine transport system, permease component I
G3W90_RS33295	COG3842	ATPase activity
G3W90_RS33300	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
G3W90_RS33325	COG0439	Biotin carboxylase
G3W90_RS33330	COG0511	ligase activity, forming carbon-carbon bonds
G3W90_RS33340	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G3W90_RS33345	COG2721	sulfolactate sulfo-lyase activity
G3W90_RS33360	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
G3W90_RS33365	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G3W90_RS33370	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W90_RS33395	COG0445	tRNA wobble uridine modification
G3W90_RS33400	COG3181	Tripartite tricarboxylate transporter family receptor
G3W90_RS33410	COG1960	acyl-CoA dehydrogenase activity
G3W90_RS33430	COG0318	PFAM AMP-dependent synthetase and ligase
G3W90_RS33435	COG1414	Transcriptional regulator
G3W90_RS33465	COG2079	MmgE PrpD family protein
G3W90_RS33470	COG1053	succinate dehydrogenase
G3W90_RS33475	COG2079	MmgE PrpD family protein
G3W90_RS33480	COG0523	cobalamin synthesis protein
G3W90_RS33490	COG1335	isochorismatase
G3W90_RS33500	COG3550	peptidyl-serine autophosphorylation
G3W90_RS33505	COG1760	l-serine dehydratase
G3W90_RS33515	COG1335	isochorismatase
G3W90_RS33530	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G3W90_RS33535	COG4569	acetaldehyde dehydrogenase (acetylating) activity
G3W90_RS33645	COG2207	Transcriptional regulator
G3W90_RS33650	COG0789	Transcriptional regulator
G3W90_RS33695	COG3181	Tripartite tricarboxylate transporter family receptor
G3W90_RS33700	COG0235	Class ii aldolase
G3W90_RS33705	COG1024	Enoyl-CoA hydratase
G3W90_RS33715	COG3119	arylsulfatase activity
G3W90_RS33755	COG3284	Transcriptional regulator
G3W90_RS33765	COG1917	Cupin 2, conserved barrel domain protein
G3W90_RS33775	COG3181	Tripartite tricarboxylate transporter family receptor
G3W90_RS33785	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G3W90_RS33790	COG4569	acetaldehyde dehydrogenase (acetylating) activity
G3W90_RS33805	COG0583	DNA-binding transcription factor activity
G3W90_RS33810	COG0583	DNA-binding transcription factor activity
G3W90_RS33825	COG3181	Tripartite tricarboxylate transporter family receptor
G3W90_RS33830	COG2814	Major facilitator Superfamily
G3W90_RS33845	COG3639	organic phosphonate transmembrane transporter activity
G3W90_RS33850	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
G3W90_RS33855	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
G3W90_RS33860	COG3454	Phosphonate metabolism
G3W90_RS33865	COG4778	phosphonate C-P lyase system protein PhnL
G3W90_RS33870	COG4107	phosphonate C-P lyase system protein PhnK
G3W90_RS33875	COG3627	carbon phosphorus lyase activity
G3W90_RS33880	COG3626	phosphonate metabolism
G3W90_RS33890	COG3624	Phosphonate C-P lyase system protein PhnG
G3W90_RS33895	COG1609	Transcriptional regulator
G3W90_RS33900	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
G3W90_RS33905	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
G3W90_RS33945	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G3W90_RS33950	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G3W90_RS33960	COG1045	serine acetyltransferase
G3W90_RS33990	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G3W90_RS33995	COG0583	DNA-binding transcription factor activity
G3W90_RS34010	COG1175	transmembrane transport
G3W90_RS34020	COG3842	ATPase activity
G3W90_RS34060	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
G3W90_RS34075	COG3181	Tripartite tricarboxylate transporter family receptor
G3W90_RS34105	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
G3W90_RS34110	COG1960	acyl-CoA dehydrogenase activity
G3W90_RS34125	COG0183	Belongs to the thiolase family
G3W90_RS34130	COG2030	dehydratase
G3W90_RS34140	COG0583	DNA-binding transcription factor activity
G3W90_RS34145	COG3976	FMN-binding domain protein
G3W90_RS34145	COG1053	succinate dehydrogenase
G3W90_RS34145	COG0431	NADPH-dependent FMN reductase
G3W90_RS34195	COG1028	Short-chain dehydrogenase reductase Sdr
G3W90_RS34200	COG1802	Transcriptional regulator
G3W90_RS34205	COG1024	Enoyl-CoA hydratase
G3W90_RS34220	COG1960	acyl-CoA dehydrogenase activity
G3W90_RS34225	COG1960	acyl-CoA dehydrogenase activity
G3W90_RS34235	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W90_RS34240	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G3W90_RS34260	COG3181	Tripartite tricarboxylate transporter family receptor
G3W90_RS34280	COG1960	acyl-CoA dehydrogenase activity
G3W90_RS34300	COG1024	Enoyl-CoA hydratase
G3W90_RS34310	COG1902	pentaerythritol trinitrate reductase activity
G3W90_RS34315	COG1024	Enoyl-CoA hydratase
G3W90_RS34320	COG1960	acyl-CoA dehydrogenase activity
G3W90_RS34330	COG1024	Enoyl-CoA hydratase
G3W90_RS34335	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W90_RS34340	COG1960	acyl-CoA dehydrogenase activity
G3W90_RS34345	COG1960	acyl-CoA dehydrogenase activity
G3W90_RS34350	COG1024	Enoyl-CoA hydratase
G3W90_RS34355	COG0318	PFAM AMP-dependent synthetase and ligase
G3W90_RS34380	COG1028	Short-chain dehydrogenase reductase Sdr
G3W90_RS34385	COG1024	Enoyl-CoA hydratase
G3W90_RS34400	COG1960	acyl-CoA dehydrogenase activity
G3W90_RS34405	COG1960	acyl-CoA dehydrogenase activity
G3W90_RS34410	COG1024	Enoyl-CoA hydratase
G3W90_RS34415	COG1028	Short-chain dehydrogenase reductase Sdr
G3W90_RS34420	COG2030	dehydratase
G3W90_RS34430	COG0583	DNA-binding transcription factor activity
G3W90_RS34435	COG1028	Short-chain dehydrogenase reductase Sdr
G3W90_RS34440	COG2070	2-Nitropropane dioxygenase
G3W90_RS34445	COG2130	NADP-dependent
G3W90_RS34465	COG0651	ATP synthesis coupled electron transport
G3W90_RS34480	COG0651	ATP synthesis coupled electron transport
G3W90_RS34485	COG0649	NAD binding
G3W90_RS34485	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G3W90_RS34490	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G3W90_RS34515	COG0651	ATP synthesis coupled electron transport
G3W90_RS34520	COG0650	Formate hydrogenlyase subunit 4
G3W90_RS34530	COG0651	ATP synthesis coupled electron transport
G3W90_RS34535	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
G3W90_RS34535	COG3261	NADH dehydrogenase
G3W90_RS34540	COG3260	NADH ubiquinone oxidoreductase 20
G3W90_RS34550	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
G3W90_RS34570	COG1872	DUF167
G3W90_RS34690	COG4584	PFAM Integrase catalytic
G3W90_RS34695	COG1484	DNA-dependent DNA replication
G3W90_RS34815	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
G3W90_RS34835	COG1121	(ABC) transporter
G3W90_RS34915	COG3701	Conjugal transfer protein
G3W90_RS34920	COG3451	type IV secretory pathway VirB4
G3W90_RS34925	COG5268	conjugation
G3W90_RS34930	COG3838	Conjugal transfer protein Trbc
G3W90_RS34935	COG4962	Type ii secretion system protein e