locus-tag	class	description
WDLP6_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
WDLP6_RS00030	COG1408	metallophosphoesterase
WDLP6_RS00040	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
WDLP6_RS00050	COG0632	four-way junction helicase activity
WDLP6_RS00055	COG0392	lysyltransferase activity
WDLP6_RS00060	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WDLP6_RS00065	COG3568	Endonuclease Exonuclease Phosphatase
WDLP6_RS00095	COG1178	ABC-type Fe3 transport system permease component
WDLP6_RS00100	COG1176	ABC-type spermidine putrescine transport system, permease component I
WDLP6_RS00110	COG3842	ATPase activity
WDLP6_RS00115	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
WDLP6_RS00140	COG2205	protein histidine kinase activity
WDLP6_RS00145	COG0745	RESPONSE REGULATOR receiver
WDLP6_RS00155	COG2217	Heavy metal translocating P-type atpase
WDLP6_RS00165	COG0642	Histidine kinase
WDLP6_RS00170	COG1902	pentaerythritol trinitrate reductase activity
WDLP6_RS00175	COG0477	Major facilitator Superfamily
WDLP6_RS00195	COG0445	tRNA wobble uridine modification
WDLP6_RS00200	COG0357	Ribosomal RNA small subunit methyltransferase G
WDLP6_RS00210	COG1192	Involved in chromosome partitioning
WDLP6_RS00220	COG1475	DNA binding
WDLP6_RS00230	COG0277	FAD linked oxidase domain protein
WDLP6_RS00235	COG2096	Adenosyltransferase
WDLP6_RS00270	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
WDLP6_RS00280	COG0850	regulation of cytokinetic process
WDLP6_RS00290	COG2233	PERMEase
WDLP6_RS00295	COG2050	protein possibly involved in aromatic compounds catabolism
WDLP6_RS00310	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
WDLP6_RS00340	COG1250	3-hydroxyacyl-CoA dehydrogenase
WDLP6_RS00345	COG3246	L-lysine catabolic process to acetate
WDLP6_RS00395	COG3550	peptidyl-serine autophosphorylation
WDLP6_RS00400	COG2233	PERMEase
WDLP6_RS00405	COG1192	Involved in chromosome partitioning
WDLP6_RS00455	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
WDLP6_RS00475	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
WDLP6_RS00500	COG0583	DNA-binding transcription factor activity
WDLP6_RS00510	COG3181	Tripartite tricarboxylate transporter family receptor
WDLP6_RS00515	COG2205	protein histidine kinase activity
WDLP6_RS00515	COG0745	RESPONSE REGULATOR receiver
WDLP6_RS00515	COG3292	Two component regulator propeller
WDLP6_RS00520	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
WDLP6_RS00540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WDLP6_RS00540	COG2205	protein histidine kinase activity
WDLP6_RS00545	COG0484	heat shock protein binding
WDLP6_RS00555	COG1028	Short-chain dehydrogenase reductase Sdr
WDLP6_RS00575	COG0745	RESPONSE REGULATOR receiver
WDLP6_RS00590	COG0740	serine-type endopeptidase activity
WDLP6_RS00595	COG0596	Alpha beta hydrolase
WDLP6_RS00600	COG1393	Belongs to the ArsC family
WDLP6_RS00640	COG3842	ATPase activity
WDLP6_RS00645	COG1176	ABC-type spermidine putrescine transport system, permease component I
WDLP6_RS00650	COG1177	transmembrane transport
WDLP6_RS00665	COG0251	oxidation-reduction process
WDLP6_RS00675	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
WDLP6_RS00680	COG2267	carboxylic ester hydrolase activity
WDLP6_RS00690	COG1228	amidohydrolase
WDLP6_RS00705	COG3181	Tripartite tricarboxylate transporter family receptor
WDLP6_RS00720	COG0181	hydroxymethylbilane synthase activity
WDLP6_RS00745	COG2226	methyltransferase
WDLP6_RS00750	COG0791	NLP P60 protein
WDLP6_RS00775	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
WDLP6_RS00785	COG0596	Alpha beta hydrolase
WDLP6_RS00790	COG2205	protein histidine kinase activity
WDLP6_RS00815	COG1051	belongs to the nudix hydrolase family
WDLP6_RS00845	COG0724	RNA recognition motif
WDLP6_RS00865	COG3813	Protein conserved in bacteria
WDLP6_RS00880	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WDLP6_RS00890	COG1024	Enoyl-CoA hydratase
WDLP6_RS00900	COG0604	alcohol dehydrogenase
WDLP6_RS00905	COG0583	DNA-binding transcription factor activity
WDLP6_RS00910	COG0318	PFAM AMP-dependent synthetase and ligase
WDLP6_RS00920	COG0583	DNA-binding transcription factor activity
WDLP6_RS00930	COG1024	Enoyl-CoA hydratase
WDLP6_RS00945	COG1028	Short-chain dehydrogenase reductase Sdr
WDLP6_RS00970	COG2205	protein histidine kinase activity
WDLP6_RS00980	COG2172	sigma factor antagonist activity
WDLP6_RS00985	COG1366	Belongs to the anti-sigma-factor antagonist family
WDLP6_RS00990	COG1366	Belongs to the anti-sigma-factor antagonist family
WDLP6_RS01000	COG0739	heme binding
WDLP6_RS01020	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
WDLP6_RS01040	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
WDLP6_RS01045	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
WDLP6_RS01050	COG1950	PFAM Membrane protein of
WDLP6_RS01070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WDLP6_RS01075	COG0450	alkyl hydroperoxide reductase
WDLP6_RS01080	COG0583	DNA-binding transcription factor activity
WDLP6_RS01085	COG1960	acyl-CoA dehydrogenase activity
WDLP6_RS01090	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WDLP6_RS01110	COG4221	oxidoreductase activity
WDLP6_RS01130	COG3321	synthase
WDLP6_RS01130	COG1028	Short-chain dehydrogenase reductase Sdr
WDLP6_RS01130	COG0604	alcohol dehydrogenase
WDLP6_RS01135	COG3246	L-lysine catabolic process to acetate
WDLP6_RS01145	COG3485	protocatechuate 3,4-dioxygenase
WDLP6_RS01150	COG1609	Transcriptional regulator
WDLP6_RS01155	COG0515	serine threonine protein kinase
WDLP6_RS01170	COG2066	Belongs to the glutaminase family
WDLP6_RS01175	COG0697	spore germination
WDLP6_RS01185	COG0402	S-adenosylhomocysteine deaminase activity
WDLP6_RS01200	COG2188	Transcriptional regulator
WDLP6_RS01205	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
WDLP6_RS01210	COG0700	Nucleoside recognition
WDLP6_RS01215	COG3540	Alkaline phosphatase
WDLP6_RS01235	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
WDLP6_RS01240	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
WDLP6_RS01245	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
WDLP6_RS01280	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WDLP6_RS01295	COG2986	histidine ammonia-lyase
WDLP6_RS01300	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
WDLP6_RS01315	COG3181	Tripartite tricarboxylate transporter family receptor
WDLP6_RS01325	COG1228	amidohydrolase
WDLP6_RS01365	COG0583	DNA-binding transcription factor activity
WDLP6_RS01380	COG0646	methionine synthase
WDLP6_RS01380	COG1410	methionine synthase
WDLP6_RS01425	COG3210	domain, Protein
WDLP6_RS01435	COG1309	transcriptional regulator
WDLP6_RS01485	COG1335	isochorismatase
WDLP6_RS01490	COG2080	2 iron, 2 sulfur cluster binding
WDLP6_RS01495	COG2010	Cytochrome c
WDLP6_RS01495	COG1529	Aldehyde oxidase and xanthine dehydrogenase
WDLP6_RS01515	COG3181	Tripartite tricarboxylate transporter family receptor
WDLP6_RS01525	COG0606	chelatase, subunit chli
WDLP6_RS01535	COG0347	Belongs to the P(II) protein family
WDLP6_RS01540	COG0004	ammonium transporteR
WDLP6_RS01550	COG0277	FAD linked oxidase domain protein
WDLP6_RS01555	COG0247	lactate metabolic process
WDLP6_RS01570	COG0386	Belongs to the glutathione peroxidase family
WDLP6_RS01580	COG0477	Major facilitator Superfamily
WDLP6_RS01585	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
WDLP6_RS01590	COG3493	citrate carrier protein
WDLP6_RS01595	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
WDLP6_RS01605	COG3181	Tripartite tricarboxylate transporter family receptor
WDLP6_RS01610	COG0129	dihydroxy-acid dehydratase activity
WDLP6_RS01620	COG3971	2-oxopent-4-enoate hydratase activity
WDLP6_RS01630	COG3384	dioxygenase
WDLP6_RS01635	COG1012	belongs to the aldehyde dehydrogenase family
WDLP6_RS01655	COG1846	Transcriptional regulator
WDLP6_RS01665	COG1053	succinate dehydrogenase
WDLP6_RS01675	COG1028	Short-chain dehydrogenase reductase Sdr
WDLP6_RS01695	COG0559	Belongs to the binding-protein-dependent transport system permease family
WDLP6_RS01705	COG1028	Short-chain dehydrogenase reductase Sdr
WDLP6_RS01720	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
WDLP6_RS01730	COG2974	May be involved in recombination
WDLP6_RS01760	COG0745	RESPONSE REGULATOR receiver
WDLP6_RS01800	COG4221	oxidoreductase activity
WDLP6_RS01815	COG0583	DNA-binding transcription factor activity
WDLP6_RS01820	COG0708	Exodeoxyribonuclease III
WDLP6_RS01825	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
WDLP6_RS01835	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
WDLP6_RS01840	COG0154	amidase activity
WDLP6_RS01845	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
WDLP6_RS01850	COG1077	Cell shape determining protein MreB Mrl
WDLP6_RS01865	COG0768	penicillin binding
WDLP6_RS01875	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
WDLP6_RS01880	COG1127	ABC transporter
WDLP6_RS01900	COG2095	MarC family integral membrane protein
WDLP6_RS01905	COG1028	Short-chain dehydrogenase reductase Sdr
WDLP6_RS01915	COG0412	Dienelactone hydrolase
WDLP6_RS01925	COG0598	Magnesium transport protein CorA
WDLP6_RS01945	COG3411	Ferredoxin
WDLP6_RS01950	COG2945	thiolester hydrolase activity
WDLP6_RS01955	COG1686	Belongs to the peptidase S11 family
WDLP6_RS01960	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
WDLP6_RS01965	COG0049	tRNA binding
WDLP6_RS01970	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
WDLP6_RS01975	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
WDLP6_RS01980	COG0051	transcription antitermination factor activity, RNA binding
WDLP6_RS01995	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
WDLP6_RS02000	COG0088	Forms part of the polypeptide exit tunnel
WDLP6_RS02005	COG0089	rRNA binding
WDLP6_RS02010	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
WDLP6_RS02015	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
WDLP6_RS02020	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
WDLP6_RS02025	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
WDLP6_RS02030	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
WDLP6_RS02035	COG0255	Belongs to the universal ribosomal protein uL29 family
WDLP6_RS02040	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
WDLP6_RS02045	COG0678	peroxiredoxin activity
WDLP6_RS02050	COG0456	acetyltransferase
WDLP6_RS02060	COG3909	cytochrome
WDLP6_RS02065	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
WDLP6_RS02080	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
WDLP6_RS02085	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
WDLP6_RS02105	COG3850	Histidine kinase
WDLP6_RS02105	COG5002	protein histidine kinase activity
WDLP6_RS02110	COG2130	NADP-dependent
WDLP6_RS02120	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
WDLP6_RS02125	COG0318	PFAM AMP-dependent synthetase and ligase
WDLP6_RS02130	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
WDLP6_RS02135	COG0321	lipoyl(octanoyl) transferase activity
WDLP6_RS02140	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
WDLP6_RS02150	COG0356	it plays a direct role in the translocation of protons across the membrane
WDLP6_RS02160	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
WDLP6_RS02165	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
WDLP6_RS02170	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
WDLP6_RS02175	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
WDLP6_RS02180	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
WDLP6_RS02185	COG0355	proton-transporting ATP synthase activity, rotational mechanism
WDLP6_RS02200	COG1172	Belongs to the binding-protein-dependent transport system permease family
WDLP6_RS02205	COG1879	ABC-type sugar transport system periplasmic component
WDLP6_RS02210	COG0673	inositol 2-dehydrogenase activity
WDLP6_RS02250	COG1793	dna ligase
WDLP6_RS02250	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
WDLP6_RS02255	COG1793	dna ligase
WDLP6_RS02260	COG1201	RNA secondary structure unwinding
WDLP6_RS02320	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WDLP6_RS02330	COG1309	transcriptional regulator
WDLP6_RS02355	COG0596	Alpha beta hydrolase
WDLP6_RS02370	COG0477	Major facilitator Superfamily
WDLP6_RS02410	COG0028	Belongs to the TPP enzyme family
WDLP6_RS02420	COG3386	PFAM SMP-30 Gluconolaconase
WDLP6_RS02435	COG1012	belongs to the aldehyde dehydrogenase family
WDLP6_RS02440	COG1879	ABC-type sugar transport system periplasmic component
WDLP6_RS02445	COG4213	ABC transporter substrate-binding protein
WDLP6_RS02455	COG4214	carbohydrate transport
WDLP6_RS02460	COG1129	ABC transporter
WDLP6_RS02465	COG1172	Belongs to the binding-protein-dependent transport system permease family
WDLP6_RS02470	COG1172	Belongs to the binding-protein-dependent transport system permease family
WDLP6_RS02505	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
WDLP6_RS02610	COG2204	response regulator
WDLP6_RS02620	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
WDLP6_RS02625	COG0792	nuclease activity
WDLP6_RS02630	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
WDLP6_RS02640	COG2084	Dehydrogenase
WDLP6_RS02665	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
WDLP6_RS02690	COG0010	Belongs to the arginase family
WDLP6_RS02695	COG3639	organic phosphonate transmembrane transporter activity
WDLP6_RS02700	COG3639	organic phosphonate transmembrane transporter activity
WDLP6_RS02705	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
WDLP6_RS02710	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
WDLP6_RS02715	COG1262	PFAM Formylglycine-generating sulfatase enzyme
WDLP6_RS02725	COG0709	Synthesizes selenophosphate from selenide and ATP
WDLP6_RS02740	COG1309	transcriptional regulator
WDLP6_RS02760	COG2124	cytochrome p450
WDLP6_RS02760	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
WDLP6_RS02780	COG0439	Biotin carboxylase
WDLP6_RS02795	COG1346	cytolysis
WDLP6_RS02800	COG1380	Effector of murein hydrolase LrgA
WDLP6_RS02805	COG0277	FAD linked oxidase domain protein
WDLP6_RS02870	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WDLP6_RS02920	COG1473	amidohydrolase
WDLP6_RS02985	COG0343	queuine tRNA-ribosyltransferase activity
WDLP6_RS02990	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
WDLP6_RS02995	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
WDLP6_RS03005	COG0783	Belongs to the Dps family
WDLP6_RS03010	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
WDLP6_RS03020	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
WDLP6_RS03025	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
WDLP6_RS03030	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
WDLP6_RS03035	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
WDLP6_RS03040	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
WDLP6_RS03045	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
WDLP6_RS03050	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
WDLP6_RS03055	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
WDLP6_RS03060	COG1841	ribosomal large subunit assembly
WDLP6_RS03065	COG0200	Binds to the 23S rRNA
WDLP6_RS03070	COG0201	protein transport
WDLP6_RS03080	COG0257	Belongs to the bacterial ribosomal protein bL36 family
WDLP6_RS03085	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
WDLP6_RS03090	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
WDLP6_RS03095	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
WDLP6_RS03100	COG0202	RNA polymerase activity
WDLP6_RS03105	COG0203	ribosomal protein L17
WDLP6_RS03125	COG1960	acyl-CoA dehydrogenase activity
WDLP6_RS03130	COG1024	Enoyl-CoA hydratase
WDLP6_RS03145	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
WDLP6_RS03160	COG0583	DNA-binding transcription factor activity
WDLP6_RS03165	COG1028	Short-chain dehydrogenase reductase Sdr
WDLP6_RS03170	COG0022	dehydrogenase e1 component
WDLP6_RS03175	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
WDLP6_RS03225	COG0693	protein deglycase activity
WDLP6_RS03260	COG1022	Amp-dependent synthetase and ligase
WDLP6_RS03265	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
WDLP6_RS03275	COG1028	Short-chain dehydrogenase reductase Sdr
WDLP6_RS03295	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
WDLP6_RS03300	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
WDLP6_RS03305	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
WDLP6_RS03310	COG2205	protein histidine kinase activity
WDLP6_RS03315	COG0745	RESPONSE REGULATOR receiver
WDLP6_RS03320	COG1187	pseudouridine synthase activity
WDLP6_RS03325	COG0745	RESPONSE REGULATOR receiver
WDLP6_RS03380	COG0326	Molecular chaperone. Has ATPase activity
WDLP6_RS03385	COG2124	cytochrome p450
WDLP6_RS03390	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
WDLP6_RS03400	COG1764	response to oxidative stress
WDLP6_RS03405	COG1846	Transcriptional regulator
WDLP6_RS03415	COG1250	3-hydroxyacyl-CoA dehydrogenase
WDLP6_RS03420	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
WDLP6_RS03445	COG0559	Belongs to the binding-protein-dependent transport system permease family
WDLP6_RS03495	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WDLP6_RS03515	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WDLP6_RS03550	COG2268	Band 7 protein
WDLP6_RS03555	COG5564	TIM-barrel signal transduction protein
WDLP6_RS03560	COG5441	Belongs to the UPF0261 family
WDLP6_RS03590	COG1228	amidohydrolase
WDLP6_RS03595	COG1228	amidohydrolase
WDLP6_RS03600	COG0596	Alpha beta hydrolase
WDLP6_RS03605	COG0179	Fumarylacetoacetate (FAA) hydrolase
WDLP6_RS03635	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
WDLP6_RS03640	COG1652	LysM domain
WDLP6_RS03665	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
WDLP6_RS03705	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WDLP6_RS03710	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
WDLP6_RS03720	COG0640	Transcriptional regulator
WDLP6_RS03735	COG0625	glutathione transferase activity
WDLP6_RS03740	COG0583	DNA-binding transcription factor activity
WDLP6_RS03745	COG1131	(ABC) transporter
WDLP6_RS03750	COG0842	Transport permease protein
WDLP6_RS03760	COG2733	membrane
WDLP6_RS03770	COG1473	amidohydrolase
WDLP6_RS03785	COG0243	molybdopterin cofactor binding
WDLP6_RS03855	COG1216	Glycosyl transferase, family 2
WDLP6_RS03875	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
WDLP6_RS03880	COG0438	transferase activity, transferring glycosyl groups
WDLP6_RS03880	COG1216	Glycosyl transferase, family 2
WDLP6_RS03900	COG0662	Cupin 2, conserved barrel domain protein
WDLP6_RS03900	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
WDLP6_RS03905	COG2755	lipolytic protein G-D-S-L family
WDLP6_RS03905	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
WDLP6_RS03910	COG1216	Glycosyl transferase, family 2
WDLP6_RS03910	COG0438	transferase activity, transferring glycosyl groups
WDLP6_RS03930	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
WDLP6_RS03940	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
WDLP6_RS03945	COG1309	transcriptional regulator
WDLP6_RS03965	COG1280	lysine exporter protein (LysE YggA)
WDLP6_RS03980	COG0628	permease
WDLP6_RS03995	COG0861	Integral membrane protein TerC family
WDLP6_RS04025	COG1028	Short-chain dehydrogenase reductase Sdr
WDLP6_RS04025	COG0604	alcohol dehydrogenase
WDLP6_RS04025	COG3321	synthase
WDLP6_RS04030	COG1917	Cupin 2, conserved barrel domain protein
WDLP6_RS04030	COG4977	sequence-specific DNA binding
WDLP6_RS04045	COG0625	glutathione transferase activity
WDLP6_RS04060	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
WDLP6_RS04065	COG0784	Response regulator, receiver
WDLP6_RS04065	COG2205	protein histidine kinase activity
WDLP6_RS04070	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
WDLP6_RS04075	COG2721	sulfolactate sulfo-lyase activity
WDLP6_RS04080	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
WDLP6_RS04090	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
WDLP6_RS04095	COG2186	Transcriptional regulator
WDLP6_RS04100	COG1028	Short-chain dehydrogenase reductase Sdr
WDLP6_RS04105	COG1028	Short-chain dehydrogenase reductase Sdr
WDLP6_RS04110	COG0179	Fumarylacetoacetate (FAA) hydrolase
WDLP6_RS04125	COG2188	Transcriptional regulator
WDLP6_RS04155	COG3181	Tripartite tricarboxylate transporter family receptor
WDLP6_RS04160	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
WDLP6_RS04165	COG0066	3-isopropylmalate dehydratase activity
WDLP6_RS04210	COG1960	acyl-CoA dehydrogenase activity
WDLP6_RS04220	COG1250	3-hydroxyacyl-CoA dehydrogenase
WDLP6_RS04220	COG1024	Enoyl-CoA hydratase
WDLP6_RS04230	COG0183	Belongs to the thiolase family
WDLP6_RS04240	COG1024	Enoyl-CoA hydratase
WDLP6_RS04245	COG1607	acyl-coa hydrolase
WDLP6_RS04250	COG5265	(ABC) transporter
WDLP6_RS04255	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
WDLP6_RS04265	COG0559	Belongs to the binding-protein-dependent transport system permease family
WDLP6_RS04270	COG1172	Belongs to the binding-protein-dependent transport system permease family
WDLP6_RS04275	COG0411	ABC transporter
WDLP6_RS04285	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WDLP6_RS04290	COG3473	Maleate cis-trans isomerase
WDLP6_RS04295	COG0596	Alpha beta hydrolase
WDLP6_RS04300	COG2309	aminopeptidase activity
WDLP6_RS04305	COG1335	isochorismatase
WDLP6_RS04315	COG0583	DNA-binding transcription factor activity
WDLP6_RS04325	COG0765	amino acid transport
WDLP6_RS04330	COG0765	amino acid transport
WDLP6_RS04335	COG1126	abc transporter atp-binding protein
WDLP6_RS04340	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
WDLP6_RS04355	COG0318	PFAM AMP-dependent synthetase and ligase
WDLP6_RS04360	COG1960	acyl-CoA dehydrogenase activity
WDLP6_RS04365	COG1960	acyl-CoA dehydrogenase activity
WDLP6_RS04370	COG0183	Belongs to the thiolase family
WDLP6_RS04380	COG0583	DNA-binding transcription factor activity
WDLP6_RS04400	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
WDLP6_RS04405	COG3386	PFAM SMP-30 Gluconolaconase
WDLP6_RS04425	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
WDLP6_RS04430	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
WDLP6_RS04450	COG0583	DNA-binding transcription factor activity
WDLP6_RS04465	COG0418	dihydroorotase activity
WDLP6_RS04505	COG1414	Transcriptional regulator
WDLP6_RS04510	COG0501	Belongs to the peptidase M48B family
WDLP6_RS04515	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
WDLP6_RS04525	COG1187	pseudouridine synthase activity
WDLP6_RS04535	COG3181	Tripartite tricarboxylate transporter family receptor
WDLP6_RS04565	COG0330	HflC and HflK could
WDLP6_RS04570	COG0598	Magnesium transport protein CorA
WDLP6_RS04585	COG3181	Tripartite tricarboxylate transporter family receptor
WDLP6_RS04615	COG2072	flavoprotein involved in K transport
WDLP6_RS04625	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
WDLP6_RS04640	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
WDLP6_RS04645	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
WDLP6_RS04650	COG0523	cobalamin synthesis protein
WDLP6_RS04665	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
WDLP6_RS04670	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
WDLP6_RS04675	COG2001	Belongs to the MraZ family
WDLP6_RS04680	COG0275	rRNA processing
WDLP6_RS04695	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
WDLP6_RS04700	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
WDLP6_RS04705	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
WDLP6_RS04710	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
WDLP6_RS04715	COG0772	Belongs to the SEDS family
WDLP6_RS04720	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
WDLP6_RS04725	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
WDLP6_RS04730	COG1181	Belongs to the D-alanine--D-alanine ligase family
WDLP6_RS04735	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
WDLP6_RS04745	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
WDLP6_RS04750	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
WDLP6_RS04755	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
WDLP6_RS04765	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
WDLP6_RS04770	COG1595	DNA-templated transcription, initiation
WDLP6_RS04790	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
WDLP6_RS04795	COG0575	Belongs to the CDS family
WDLP6_RS04845	COG3246	L-lysine catabolic process to acetate
WDLP6_RS04850	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
WDLP6_RS04860	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
WDLP6_RS04875	COG3150	esterase
WDLP6_RS04880	COG0772	Belongs to the SEDS family
WDLP6_RS04885	COG0312	modulator of DNA gyrase
WDLP6_RS04890	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
WDLP6_RS04900	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
WDLP6_RS04910	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
WDLP6_RS04915	COG0511	ligase activity, forming carbon-carbon bonds
WDLP6_RS04920	COG0439	Biotin carboxylase
WDLP6_RS04925	COG2264	protein methyltransferase activity
WDLP6_RS04935	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WDLP6_RS04945	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
WDLP6_RS04980	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
WDLP6_RS04995	COG2204	response regulator
WDLP6_RS05005	COG2205	protein histidine kinase activity
WDLP6_RS05010	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
WDLP6_RS05020	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WDLP6_RS05025	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WDLP6_RS05070	COG0037	tRNA processing
WDLP6_RS05080	COG1028	Short-chain dehydrogenase reductase Sdr
WDLP6_RS05090	COG2175	clavaminate synthase activity
WDLP6_RS05130	COG1028	Short-chain dehydrogenase reductase Sdr
WDLP6_RS05140	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WDLP6_RS05150	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
WDLP6_RS05155	COG3387	PFAM Glycoside hydrolase 15-related
WDLP6_RS05165	COG0617	tRNA 3'-terminal CCA addition
WDLP6_RS05175	COG1285	pathogenesis
WDLP6_RS05180	COG0741	lytic transglycosylase activity
WDLP6_RS05180	COG1196	nuclear chromosome segregation
WDLP6_RS05180	COG0739	heme binding
WDLP6_RS05185	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
WDLP6_RS05190	COG0583	DNA-binding transcription factor activity
WDLP6_RS05205	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
WDLP6_RS05225	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
WDLP6_RS05250	COG1053	succinate dehydrogenase
WDLP6_RS05255	COG1028	Short-chain dehydrogenase reductase Sdr
WDLP6_RS05295	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
WDLP6_RS05300	COG0477	Major facilitator Superfamily
WDLP6_RS05305	COG0697	spore germination
WDLP6_RS05310	COG1902	pentaerythritol trinitrate reductase activity
WDLP6_RS05325	COG4221	oxidoreductase activity
WDLP6_RS05345	COG3181	Tripartite tricarboxylate transporter family receptor
WDLP6_RS05355	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
WDLP6_RS05360	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
WDLP6_RS05370	COG0583	DNA-binding transcription factor activity
WDLP6_RS05385	COG2081	HI0933 family
WDLP6_RS05395	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
WDLP6_RS05400	COG0596	Alpha beta hydrolase
WDLP6_RS05425	COG3181	Tripartite tricarboxylate transporter family receptor
WDLP6_RS05440	COG3971	2-oxopent-4-enoate hydratase activity
WDLP6_RS05470	COG0477	Major facilitator Superfamily
WDLP6_RS05485	COG0596	Alpha beta hydrolase
WDLP6_RS05530	COG2309	aminopeptidase activity
WDLP6_RS05535	COG1335	isochorismatase
WDLP6_RS05545	COG0559	Belongs to the binding-protein-dependent transport system permease family
WDLP6_RS05570	COG3181	Tripartite tricarboxylate transporter family receptor
WDLP6_RS05580	COG1024	Enoyl-CoA hydratase
WDLP6_RS05590	COG3181	Tripartite tricarboxylate transporter family receptor
WDLP6_RS05600	COG0183	Belongs to the thiolase family
WDLP6_RS05620	COG2207	Transcriptional regulator
WDLP6_RS05645	COG0583	DNA-binding transcription factor activity
WDLP6_RS05650	COG1335	isochorismatase
WDLP6_RS05655	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WDLP6_RS05660	COG2080	2 iron, 2 sulfur cluster binding
WDLP6_RS05680	COG3181	Tripartite tricarboxylate transporter family receptor
WDLP6_RS05690	COG2309	aminopeptidase activity
WDLP6_RS05695	COG0596	Alpha beta hydrolase
WDLP6_RS05705	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
WDLP6_RS05725	COG1301	dicarboxylic acid transport
WDLP6_RS05730	COG0583	DNA-binding transcription factor activity
WDLP6_RS05740	COG2828	Protein conserved in bacteria
WDLP6_RS05745	COG0583	DNA-binding transcription factor activity
WDLP6_RS05760	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
WDLP6_RS05770	COG1529	Aldehyde oxidase and xanthine dehydrogenase
WDLP6_RS05775	COG0523	cobalamin synthesis protein
WDLP6_RS05795	COG2233	PERMEase
WDLP6_RS05905	COG0683	leucine binding
WDLP6_RS05915	COG0633	Ferredoxin
WDLP6_RS05935	COG0583	DNA-binding transcription factor activity
WDLP6_RS05940	COG2910	NAD(P)H-binding
WDLP6_RS05970	COG3483	tryptophan 2,3-dioxygenase activity
WDLP6_RS05980	COG0154	amidase activity
WDLP6_RS05990	COG0583	DNA-binding transcription factor activity
WDLP6_RS06000	COG0346	lactoylglutathione lyase activity
WDLP6_RS06005	COG0655	NAD(P)H dehydrogenase (quinone) activity
WDLP6_RS06025	COG0154	amidase activity
WDLP6_RS06035	COG3181	Tripartite tricarboxylate transporter family receptor
WDLP6_RS06040	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
WDLP6_RS06050	COG2207	Transcriptional regulator
WDLP6_RS06055	COG2208	phosphoserine phosphatase activity
WDLP6_RS06075	COG2172	sigma factor antagonist activity
WDLP6_RS06110	COG3038	cytochrome b561
WDLP6_RS06115	COG2814	Major facilitator Superfamily
WDLP6_RS06120	COG0583	DNA-binding transcription factor activity
WDLP6_RS06135	COG1640	4-alpha-glucanotransferase
WDLP6_RS06140	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
WDLP6_RS06150	COG0668	transmembrane transport
WDLP6_RS06155	COG0366	Alpha amylase catalytic
WDLP6_RS06160	COG0366	Alpha amylase catalytic
WDLP6_RS06165	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
WDLP6_RS06195	COG0189	ligase activity
WDLP6_RS06195	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
WDLP6_RS06200	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
WDLP6_RS06200	COG0189	ligase activity
WDLP6_RS06205	COG1132	(ABC) transporter
WDLP6_RS06215	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
WDLP6_RS06220	COG4178	(ABC) transporter
WDLP6_RS06295	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
WDLP6_RS06300	COG1765	OsmC-like protein
WDLP6_RS06305	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
WDLP6_RS06320	COG1473	amidohydrolase
WDLP6_RS06325	COG0747	negative chemotaxis
WDLP6_RS06330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WDLP6_RS06335	COG0444	Belongs to the ABC transporter superfamily
WDLP6_RS06340	COG4608	Belongs to the ABC transporter superfamily
WDLP6_RS06345	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
WDLP6_RS06360	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
WDLP6_RS06365	COG0166	Belongs to the GPI family
WDLP6_RS06375	COG0459	protein refolding
WDLP6_RS06380	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
WDLP6_RS06395	COG4772	TonB-dependent receptor
WDLP6_RS06405	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
WDLP6_RS06415	COG1560	Kdo2-lipid A biosynthetic process
WDLP6_RS06425	COG0218	Necessary for normal cell division and for the maintenance of normal septation
WDLP6_RS06435	COG1333	cytochrome c biogenesis protein
WDLP6_RS06440	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
WDLP6_RS06445	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
WDLP6_RS06450	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
WDLP6_RS06465	COG1965	Belongs to the frataxin family
WDLP6_RS06500	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
WDLP6_RS06510	COG0232	Belongs to the dGTPase family. Type 2 subfamily
WDLP6_RS06535	COG0070	glutamate synthase
WDLP6_RS06535	COG0067	glutamate synthase
WDLP6_RS06535	COG0069	glutamate synthase activity
WDLP6_RS06545	COG1127	ABC transporter
WDLP6_RS06550	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
WDLP6_RS06555	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
WDLP6_RS06560	COG2853	Lipoprotein
WDLP6_RS06575	COG1131	(ABC) transporter
WDLP6_RS06580	COG0842	Transport permease protein
WDLP6_RS06585	COG5007	Belongs to the BolA IbaG family
WDLP6_RS06590	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
WDLP6_RS06595	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
WDLP6_RS06610	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
WDLP6_RS06615	COG0131	Imidazoleglycerol-phosphate dehydratase
WDLP6_RS06625	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
WDLP6_RS06640	COG0107	imidazoleglycerol-phosphate synthase activity
WDLP6_RS06645	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
WDLP6_RS06650	COG0140	phosphoribosyl-ATP diphosphatase activity
WDLP6_RS06660	COG0537	adenosine 5'-monophosphoramidase activity
WDLP6_RS06665	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
WDLP6_RS06670	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
WDLP6_RS06675	COG0805	protein transport
WDLP6_RS06680	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WDLP6_RS06685	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
WDLP6_RS06690	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
WDLP6_RS06695	COG1970	mechanosensitive ion channel activity
WDLP6_RS06700	COG0723	plastoquinol--plastocyanin reductase activity
WDLP6_RS06705	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
WDLP6_RS06710	COG2857	Cytochrome c1
WDLP6_RS06715	COG0625	glutathione transferase activity
WDLP6_RS06720	COG2969	positive regulation of protein catabolic process
WDLP6_RS06740	COG0798	PFAM Bile acid sodium symporter
WDLP6_RS06745	COG0431	NADPH-dependent FMN reductase
WDLP6_RS06755	COG2860	membrane
WDLP6_RS06790	COG0653	protein targeting
WDLP6_RS06795	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
WDLP6_RS06805	COG0494	nUDIX hydrolase
WDLP6_RS06810	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
WDLP6_RS06815	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
WDLP6_RS06825	COG1696	Membrane protein involved in D-alanine export
WDLP6_RS06835	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
WDLP6_RS06855	COG0438	transferase activity, transferring glycosyl groups
WDLP6_RS06875	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
WDLP6_RS06885	COG1686	Belongs to the peptidase S11 family
WDLP6_RS06900	COG0463	Glycosyl transferase, family 2
WDLP6_RS06905	COG0165	Argininosuccinate lyase
WDLP6_RS06910	COG3275	phosphorelay sensor kinase activity
WDLP6_RS06920	COG0628	permease
WDLP6_RS06930	COG0477	Major facilitator Superfamily
WDLP6_RS06965	COG1028	Short-chain dehydrogenase reductase Sdr
WDLP6_RS06970	COG1063	alcohol dehydrogenase
WDLP6_RS06985	COG1172	Belongs to the binding-protein-dependent transport system permease family
WDLP6_RS07015	COG4948	Mandelate Racemase Muconate Lactonizing
WDLP6_RS07035	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
WDLP6_RS07060	COG0142	geranyltranstransferase activity
WDLP6_RS07065	COG0261	This protein binds to 23S rRNA in the presence of protein L20
WDLP6_RS07070	COG0211	Belongs to the bacterial ribosomal protein bL27 family
WDLP6_RS07075	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
WDLP6_RS07080	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
WDLP6_RS07090	COG0494	nUDIX hydrolase
WDLP6_RS07095	COG0442	prolyl-tRNA aminoacylation
WDLP6_RS07100	COG0741	lytic transglycosylase activity
WDLP6_RS07105	COG1253	flavin adenine dinucleotide binding
WDLP6_RS07110	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
WDLP6_RS07120	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
WDLP6_RS07125	COG2890	protein-(glutamine-N5) methyltransferase activity
WDLP6_RS07130	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
WDLP6_RS07135	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
WDLP6_RS07145	COG1196	nuclear chromosome segregation
WDLP6_RS07145	COG3264	Mechanosensitive ion channel
WDLP6_RS07150	COG0584	glycerophosphoryl diester phosphodiesterase
WDLP6_RS07155	COG3842	ATPase activity
WDLP6_RS07160	COG0395	ABC-type sugar transport system, permease component
WDLP6_RS07165	COG1175	transmembrane transport
WDLP6_RS07175	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
WDLP6_RS07195	COG2226	methyltransferase
WDLP6_RS07210	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
WDLP6_RS07215	COG4145	pantothenate transmembrane transporter activity
WDLP6_RS07230	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
WDLP6_RS07235	COG0494	nUDIX hydrolase
WDLP6_RS07245	COG0302	gtp cyclohydrolase
WDLP6_RS07280	COG5487	UPF0391 membrane protein
WDLP6_RS07285	COG4585	Histidine kinase
WDLP6_RS07290	COG2197	response regulator
WDLP6_RS07305	COG2982	Protein involved in outer membrane biogenesis
WDLP6_RS07310	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
WDLP6_RS07315	COG0793	Belongs to the peptidase S41A family
WDLP6_RS07320	COG0588	phosphoglycerate mutase activity
WDLP6_RS07325	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
WDLP6_RS07335	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
WDLP6_RS07340	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
WDLP6_RS07350	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
WDLP6_RS07360	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
WDLP6_RS07365	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
WDLP6_RS07370	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
WDLP6_RS07375	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
WDLP6_RS07395	COG0659	secondary active sulfate transmembrane transporter activity
WDLP6_RS07405	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
WDLP6_RS07405	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
WDLP6_RS07410	COG3132	Protein of unknown function, DUF480
WDLP6_RS07420	COG0583	DNA-binding transcription factor activity
WDLP6_RS07425	COG0489	protein tyrosine kinase activity
WDLP6_RS07445	COG3383	formate dehydrogenase (NAD+) activity
WDLP6_RS07450	COG0463	Glycosyl transferase, family 2
WDLP6_RS07455	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
WDLP6_RS07495	COG0437	4 iron, 4 sulfur cluster binding
WDLP6_RS07515	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
WDLP6_RS07525	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
WDLP6_RS07535	COG0626	cystathionine gamma-synthase activity
WDLP6_RS07540	COG1414	Transcriptional regulator
WDLP6_RS07545	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
WDLP6_RS07550	COG2376	Dihydroxyacetone kinase
WDLP6_RS07560	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
WDLP6_RS07565	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
WDLP6_RS07570	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
WDLP6_RS07575	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
WDLP6_RS07580	COG0445	tRNA wobble uridine modification
WDLP6_RS07605	COG0277	FAD linked oxidase domain protein
WDLP6_RS07620	COG0247	lactate metabolic process
WDLP6_RS07625	COG1592	Rubrerythrin
WDLP6_RS07630	COG3491	Belongs to the iron ascorbate-dependent oxidoreductase family
WDLP6_RS07650	COG2003	Belongs to the UPF0758 family
WDLP6_RS07655	COG1047	Peptidyl-prolyl cis-trans
WDLP6_RS07660	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
WDLP6_RS07665	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
WDLP6_RS07675	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
WDLP6_RS07685	COG0582	viral genome integration into host DNA
WDLP6_RS07975	COG1733	regulation of RNA biosynthetic process
WDLP6_RS07980	COG1960	acyl-CoA dehydrogenase activity
WDLP6_RS07985	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
WDLP6_RS07990	COG1960	acyl-CoA dehydrogenase activity
WDLP6_RS07995	COG1028	Short-chain dehydrogenase reductase Sdr
WDLP6_RS08000	COG0427	acetyl-CoA hydrolase
WDLP6_RS08005	COG0183	Belongs to the thiolase family
WDLP6_RS08010	COG2030	dehydratase
WDLP6_RS08040	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
WDLP6_RS08060	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WDLP6_RS08070	COG1902	pentaerythritol trinitrate reductase activity
WDLP6_RS08075	COG0402	S-adenosylhomocysteine deaminase activity
WDLP6_RS08080	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
WDLP6_RS08130	COG1028	Short-chain dehydrogenase reductase Sdr
WDLP6_RS08135	COG2239	Acts as a magnesium transporter
WDLP6_RS08140	COG2902	Dehydrogenase
WDLP6_RS08150	COG5002	protein histidine kinase activity
WDLP6_RS08160	COG0180	Tryptophanyl-tRNA synthetase
WDLP6_RS08165	COG1994	Peptidase M50
WDLP6_RS08170	COG0009	L-threonylcarbamoyladenylate synthase
WDLP6_RS08180	COG0613	PHP domain protein
WDLP6_RS08210	COG1129	ABC transporter
WDLP6_RS08230	COG0477	Major facilitator Superfamily
WDLP6_RS08235	COG0829	nickel cation binding
WDLP6_RS08275	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
WDLP6_RS08315	COG1262	PFAM Formylglycine-generating sulfatase enzyme
WDLP6_RS08315	COG0515	serine threonine protein kinase
WDLP6_RS08320	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WDLP6_RS08355	COG0392	lysyltransferase activity
WDLP6_RS08370	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WDLP6_RS08375	COG1116	anion transmembrane transporter activity
WDLP6_RS08385	COG0280	phosphate acetyltransferase
WDLP6_RS08385	COG0281	malic enzyme
WDLP6_RS08395	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WDLP6_RS08400	COG0583	DNA-binding transcription factor activity
WDLP6_RS08410	COG0625	glutathione transferase activity
WDLP6_RS08415	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WDLP6_RS08445	COG1477	protein flavinylation
WDLP6_RS08450	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
WDLP6_RS08460	COG3128	pkhd-type hydroxylase
WDLP6_RS08465	COG3181	Tripartite tricarboxylate transporter family receptor
WDLP6_RS08490	COG3485	protocatechuate 3,4-dioxygenase
WDLP6_RS08495	COG0402	S-adenosylhomocysteine deaminase activity
WDLP6_RS08535	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
WDLP6_RS08555	COG3473	Maleate cis-trans isomerase
WDLP6_RS08575	COG1021	2,3-dihydroxybenzoate-AMP ligase
WDLP6_RS08595	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
WDLP6_RS08600	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
WDLP6_RS08610	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
WDLP6_RS08690	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
WDLP6_RS08695	COG0066	3-isopropylmalate dehydratase activity
WDLP6_RS08700	COG2828	Protein conserved in bacteria
WDLP6_RS08730	COG1283	sodium-dependent phosphate transmembrane transporter activity
WDLP6_RS08735	COG3181	Tripartite tricarboxylate transporter family receptor
WDLP6_RS08745	COG0583	DNA-binding transcription factor activity
WDLP6_RS08785	COG0444	Belongs to the ABC transporter superfamily
WDLP6_RS08810	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WDLP6_RS08820	COG4521	taurine ABC transporter
WDLP6_RS08825	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
WDLP6_RS08830	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WDLP6_RS08835	COG0625	glutathione transferase activity
WDLP6_RS08860	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
WDLP6_RS08865	COG1414	Transcriptional regulator
WDLP6_RS08890	COG1960	acyl-CoA dehydrogenase activity
WDLP6_RS08895	COG1042	CoA-binding domain protein
WDLP6_RS08895	COG0045	succinate-CoA ligase (ADP-forming) activity
WDLP6_RS08895	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WDLP6_RS08915	COG0583	DNA-binding transcription factor activity
WDLP6_RS08925	COG0318	PFAM AMP-dependent synthetase and ligase
WDLP6_RS08930	COG1012	belongs to the aldehyde dehydrogenase family
WDLP6_RS08940	COG1414	Transcriptional regulator
WDLP6_RS08960	COG4964	Belongs to the GSP D family
WDLP6_RS09010	COG2197	response regulator
WDLP6_RS09015	COG4585	Histidine kinase
WDLP6_RS09035	COG1414	Transcriptional regulator
WDLP6_RS09050	COG0583	DNA-binding transcription factor activity
WDLP6_RS09055	COG0243	molybdopterin cofactor binding
WDLP6_RS09060	COG0437	4 iron, 4 sulfur cluster binding
WDLP6_RS09065	COG3302	dmso reductase anchor subunit
WDLP6_RS09110	COG0492	ferredoxin-NADP+ reductase activity
WDLP6_RS09135	COG1126	abc transporter atp-binding protein
WDLP6_RS09195	COG1815	bacterial-type flagellum-dependent cell motility
WDLP6_RS09210	COG1749	Flagellar hook protein flgE
WDLP6_RS09215	COG4787	bacterial-type flagellum-dependent cell motility
WDLP6_RS09225	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
WDLP6_RS09230	COG1706	bacterial-type flagellum-dependent cell motility
WDLP6_RS09235	COG3951	Flagellar rod assembly protein muramidase FlgJ
WDLP6_RS09235	COG1705	Flagellar rod assembly protein muramidase FlgJ
WDLP6_RS09240	COG0840	transmembrane signaling receptor activity
WDLP6_RS09245	COG0835	chemotaxis
WDLP6_RS09255	COG0840	transmembrane signaling receptor activity
WDLP6_RS09265	COG0840	transmembrane signaling receptor activity
WDLP6_RS09270	COG1256	bacterial-type flagellum assembly
WDLP6_RS09290	COG2020	methyltransferase activity
WDLP6_RS09295	COG2267	carboxylic ester hydrolase activity
WDLP6_RS09310	COG0432	Pfam Uncharacterised protein family UPF0047
WDLP6_RS09380	COG1338	Plays a role in the flagellum-specific transport system
WDLP6_RS09390	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
WDLP6_RS09395	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
WDLP6_RS09400	COG1580	Controls the rotational direction of flagella during chemotaxis
WDLP6_RS09415	COG1157	protein secretion by the type III secretion system
WDLP6_RS09425	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
WDLP6_RS09430	COG1766	The M ring may be actively involved in energy transduction
WDLP6_RS09435	COG1677	Flagellar hook-basal body complex protein FliE
WDLP6_RS09445	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
WDLP6_RS09465	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
WDLP6_RS09495	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
WDLP6_RS09500	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
WDLP6_RS09505	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
WDLP6_RS09520	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
WDLP6_RS09570	COG1716	ATPase activity
WDLP6_RS09575	COG4251	negative regulation of phosphorylation
WDLP6_RS09580	COG4251	negative regulation of phosphorylation
WDLP6_RS09590	COG1484	DNA-dependent DNA replication
WDLP6_RS09595	COG4584	PFAM Integrase catalytic
WDLP6_RS09630	COG4669	(LipO)protein
WDLP6_RS09705	COG4792	protein secretion
WDLP6_RS09710	COG4791	protein targeting
WDLP6_RS09715	COG4794	Type iii secretion
WDLP6_RS09720	COG4790	Type iii secretion
WDLP6_RS09770	COG4789	Type iii secretion
WDLP6_RS09795	COG0784	Response regulator, receiver
WDLP6_RS09800	COG0784	Response regulator, receiver
WDLP6_RS09800	COG2205	protein histidine kinase activity
WDLP6_RS09805	COG0129	dihydroxy-acid dehydratase activity
WDLP6_RS09830	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
WDLP6_RS09835	COG4569	acetaldehyde dehydrogenase (acetylating) activity
WDLP6_RS09845	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WDLP6_RS09870	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
WDLP6_RS09875	COG0308	aminopeptidase N
WDLP6_RS09890	COG0667	Aldo Keto reductase
WDLP6_RS09895	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
WDLP6_RS09900	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
WDLP6_RS09905	COG0251	oxidation-reduction process
WDLP6_RS09915	COG1666	GTP binding
WDLP6_RS09920	COG0812	UDP-N-acetylmuramate dehydrogenase activity
WDLP6_RS09925	COG0137	argininosuccinate synthase activity
WDLP6_RS09930	COG3123	guanosine phosphorylase activity
WDLP6_RS09940	COG1393	Belongs to the ArsC family
WDLP6_RS09945	COG0285	dihydrofolate synthase activity
WDLP6_RS09970	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
WDLP6_RS10000	COG0318	PFAM AMP-dependent synthetase and ligase
WDLP6_RS10005	COG0183	Belongs to the thiolase family
WDLP6_RS10020	COG0300	oxidoreductase activity
WDLP6_RS10025	COG2207	Transcriptional regulator
WDLP6_RS10040	COG0583	DNA-binding transcription factor activity
WDLP6_RS10045	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WDLP6_RS10050	COG1024	Enoyl-CoA hydratase
WDLP6_RS10065	COG1921	L-seryl-tRNASec selenium transferase activity
WDLP6_RS10075	COG0492	ferredoxin-NADP+ reductase activity
WDLP6_RS10105	COG1028	Short-chain dehydrogenase reductase Sdr
WDLP6_RS10110	COG1028	Short-chain dehydrogenase reductase Sdr
WDLP6_RS10115	COG3976	FMN-binding domain protein
WDLP6_RS10115	COG1053	succinate dehydrogenase
WDLP6_RS10120	COG1028	Short-chain dehydrogenase reductase Sdr
WDLP6_RS10135	COG1053	succinate dehydrogenase
WDLP6_RS10145	COG2188	Transcriptional regulator
WDLP6_RS10150	COG0683	leucine binding
WDLP6_RS10165	COG0559	Belongs to the binding-protein-dependent transport system permease family
WDLP6_RS10195	COG0583	DNA-binding transcription factor activity
WDLP6_RS10210	COG0492	ferredoxin-NADP+ reductase activity
WDLP6_RS10225	COG1529	Aldehyde oxidase and xanthine dehydrogenase
WDLP6_RS10235	COG2252	PERMEase
WDLP6_RS10260	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
WDLP6_RS10275	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
WDLP6_RS10280	COG2200	EAL domain
WDLP6_RS10280	COG3287	FIST C domain
WDLP6_RS10280	COG2199	diguanylate cyclase activity
WDLP6_RS10300	COG0402	S-adenosylhomocysteine deaminase activity
WDLP6_RS10305	COG0717	Belongs to the dCTP deaminase family
WDLP6_RS10310	COG2321	neutral zinc metallopeptidase
WDLP6_RS10315	COG0513	Belongs to the DEAD box helicase family
WDLP6_RS10320	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
WDLP6_RS10325	COG1253	flavin adenine dinucleotide binding
WDLP6_RS10345	COG2084	Dehydrogenase
WDLP6_RS10350	COG3622	Belongs to the hyi family
WDLP6_RS10355	COG3960	tartronate-semialdehyde synthase activity
WDLP6_RS10360	COG0583	DNA-binding transcription factor activity
WDLP6_RS10375	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
WDLP6_RS10380	COG1335	isochorismatase
WDLP6_RS10385	COG0251	oxidation-reduction process
WDLP6_RS10390	COG2267	carboxylic ester hydrolase activity
WDLP6_RS10395	COG0778	Nitroreductase
WDLP6_RS10400	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
WDLP6_RS10405	COG1309	transcriptional regulator
WDLP6_RS10415	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
WDLP6_RS10420	COG3842	ATPase activity
WDLP6_RS10425	COG1176	ABC-type spermidine putrescine transport system, permease component I
WDLP6_RS10430	COG1177	transmembrane transport
WDLP6_RS10440	COG2186	Transcriptional regulator
WDLP6_RS10445	COG1301	dicarboxylic acid transport
WDLP6_RS10460	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
WDLP6_RS10470	COG1064	alcohol dehydrogenase
WDLP6_RS10490	COG2267	carboxylic ester hydrolase activity
WDLP6_RS10505	COG1902	pentaerythritol trinitrate reductase activity
WDLP6_RS10515	COG0583	DNA-binding transcription factor activity
WDLP6_RS10530	COG1959	2 iron, 2 sulfur cluster binding
WDLP6_RS10545	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
WDLP6_RS10550	COG1960	acyl-CoA dehydrogenase activity
WDLP6_RS10560	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
WDLP6_RS10580	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
WDLP6_RS10590	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
WDLP6_RS10595	COG1028	Short-chain dehydrogenase reductase Sdr
WDLP6_RS10600	COG3181	Tripartite tricarboxylate transporter family receptor
WDLP6_RS10630	COG1028	Short-chain dehydrogenase reductase Sdr
WDLP6_RS10640	COG1309	transcriptional regulator
WDLP6_RS10645	COG1028	Short-chain dehydrogenase reductase Sdr
WDLP6_RS10665	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WDLP6_RS10680	COG0604	alcohol dehydrogenase
WDLP6_RS10685	COG2130	NADP-dependent
WDLP6_RS10715	COG1024	Enoyl-CoA hydratase
WDLP6_RS10735	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
WDLP6_RS10770	COG0277	FAD linked oxidase domain protein
WDLP6_RS10775	COG1522	sequence-specific DNA binding
WDLP6_RS10795	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WDLP6_RS10835	COG3901	Regulator of nitric oxide reductase transcription
WDLP6_RS10835	COG0348	domain, Protein
WDLP6_RS10860	COG0842	Transport permease protein
WDLP6_RS10860	COG1129	ABC transporter
WDLP6_RS10865	COG0535	radical SAM domain protein
WDLP6_RS10880	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
WDLP6_RS10910	COG1012	belongs to the aldehyde dehydrogenase family
WDLP6_RS10915	COG0318	PFAM AMP-dependent synthetase and ligase
WDLP6_RS10935	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
WDLP6_RS10945	COG0318	PFAM AMP-dependent synthetase and ligase
WDLP6_RS10960	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WDLP6_RS10995	COG0596	Alpha beta hydrolase
WDLP6_RS11010	COG0730	response to heat
WDLP6_RS11050	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
WDLP6_RS11065	COG0318	PFAM AMP-dependent synthetase and ligase
WDLP6_RS11070	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
WDLP6_RS11120	COG0667	Aldo Keto reductase
WDLP6_RS11125	COG3181	Tripartite tricarboxylate transporter family receptor
WDLP6_RS11130	COG0277	FAD linked oxidase domain protein
WDLP6_RS11135	COG3119	arylsulfatase activity
WDLP6_RS11140	COG0583	DNA-binding transcription factor activity
WDLP6_RS11160	COG4948	Mandelate Racemase Muconate Lactonizing
WDLP6_RS11165	COG0583	DNA-binding transcription factor activity
WDLP6_RS11185	COG2030	dehydratase
WDLP6_RS11190	COG1028	Short-chain dehydrogenase reductase Sdr
WDLP6_RS11195	COG1960	acyl-CoA dehydrogenase activity
WDLP6_RS11200	COG1960	acyl-CoA dehydrogenase activity
WDLP6_RS11205	COG3181	Tripartite tricarboxylate transporter family receptor
WDLP6_RS11210	COG0318	PFAM AMP-dependent synthetase and ligase
WDLP6_RS11215	COG0028	Belongs to the TPP enzyme family
WDLP6_RS11225	COG0583	DNA-binding transcription factor activity
WDLP6_RS11245	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
WDLP6_RS11265	COG0154	amidase activity
WDLP6_RS11270	COG0583	DNA-binding transcription factor activity
WDLP6_RS11275	COG0251	oxidation-reduction process
WDLP6_RS11305	COG1176	ABC-type spermidine putrescine transport system, permease component I
WDLP6_RS11335	COG1793	dna ligase
WDLP6_RS11340	COG4191	Histidine kinase
WDLP6_RS11340	COG0784	Response regulator, receiver
WDLP6_RS11385	COG0745	RESPONSE REGULATOR receiver
WDLP6_RS11395	COG2205	protein histidine kinase activity
WDLP6_RS11400	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
WDLP6_RS11430	COG1529	Aldehyde oxidase and xanthine dehydrogenase
WDLP6_RS11435	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
WDLP6_RS11440	COG2080	2 iron, 2 sulfur cluster binding
WDLP6_RS11450	COG2814	Major facilitator Superfamily
WDLP6_RS11455	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
WDLP6_RS11460	COG0656	L-ascorbic acid biosynthetic process
WDLP6_RS11465	COG2233	PERMEase
WDLP6_RS11485	COG3181	Tripartite tricarboxylate transporter family receptor
WDLP6_RS11495	COG3754	Rhamnan synthesis protein F
WDLP6_RS11500	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
WDLP6_RS11515	COG2186	Transcriptional regulator
WDLP6_RS11520	COG2351	hydroxyisourate hydrolase activity
WDLP6_RS11545	COG0583	DNA-binding transcription factor activity
WDLP6_RS11570	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WDLP6_RS11585	COG1131	(ABC) transporter
WDLP6_RS11590	COG0842	Transport permease protein
WDLP6_RS11595	COG0842	Transport permease protein
WDLP6_RS11625	COG0674	pyruvate-flavodoxin oxidoreductase activity
WDLP6_RS11625	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
WDLP6_RS11640	COG3468	outer membrane autotransporter barrel domain protein
WDLP6_RS11690	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WDLP6_RS11695	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
WDLP6_RS11705	COG3181	Tripartite tricarboxylate transporter family receptor
WDLP6_RS11730	COG3181	Tripartite tricarboxylate transporter family receptor
WDLP6_RS11760	COG0515	serine threonine protein kinase
WDLP6_RS11875	COG1414	Transcriptional regulator
WDLP6_RS11895	COG1024	Enoyl-CoA hydratase
WDLP6_RS11905	COG2831	hemolysin activation secretion protein
WDLP6_RS11910	COG3210	domain, Protein
WDLP6_RS11935	COG2217	Heavy metal translocating P-type atpase
WDLP6_RS11940	COG0789	Transcriptional regulator
WDLP6_RS11945	COG1529	Aldehyde oxidase and xanthine dehydrogenase
WDLP6_RS11945	COG2010	Cytochrome c
WDLP6_RS11960	COG0697	spore germination
WDLP6_RS11965	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
WDLP6_RS11970	COG2169	Transcriptional regulator
WDLP6_RS12015	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
WDLP6_RS12030	COG1309	transcriptional regulator
WDLP6_RS12035	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
WDLP6_RS12050	COG0527	aspartate kinase activity
WDLP6_RS12055	COG0667	Aldo Keto reductase
WDLP6_RS12065	COG0259	pyridoxamine-phosphate oxidase activity
WDLP6_RS12070	COG0583	DNA-binding transcription factor activity
WDLP6_RS12095	COG0800	Aldolase
WDLP6_RS12105	COG0346	lactoylglutathione lyase activity
WDLP6_RS12125	COG1840	ABC-type Fe3 transport system, periplasmic component
WDLP6_RS12130	COG0318	PFAM AMP-dependent synthetase and ligase
WDLP6_RS12135	COG2070	2-Nitropropane dioxygenase
WDLP6_RS12140	COG4221	oxidoreductase activity
WDLP6_RS12190	COG4221	oxidoreductase activity
WDLP6_RS12200	COG0800	Aldolase
WDLP6_RS12210	COG0129	dihydroxy-acid dehydratase activity
WDLP6_RS12215	COG2186	Transcriptional regulator
WDLP6_RS12225	COG1175	transmembrane transport
WDLP6_RS12235	COG3842	ATPase activity
WDLP6_RS12250	COG0513	Belongs to the DEAD box helicase family
WDLP6_RS12260	COG0488	(ABC) transporter
WDLP6_RS12270	COG1132	(ABC) transporter
WDLP6_RS12280	COG3191	aminopeptidase activity
WDLP6_RS12295	COG0584	glycerophosphoryl diester phosphodiesterase
WDLP6_RS12310	COG0765	amino acid transport
WDLP6_RS12315	COG0765	amino acid transport
WDLP6_RS12330	COG1764	response to oxidative stress
WDLP6_RS12335	COG0318	PFAM AMP-dependent synthetase and ligase
WDLP6_RS12345	COG0456	acetyltransferase
WDLP6_RS12355	COG1252	NADH dehydrogenase
WDLP6_RS12360	COG1262	PFAM Formylglycine-generating sulfatase enzyme
WDLP6_RS12365	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
WDLP6_RS12380	COG0589	response to stress
WDLP6_RS12385	COG0564	pseudouridine synthase activity
WDLP6_RS12395	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
WDLP6_RS12405	COG2354	Protein conserved in bacteria
WDLP6_RS12410	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
WDLP6_RS12420	COG3468	outer membrane autotransporter barrel domain protein
WDLP6_RS12435	COG0400	carboxylic ester hydrolase activity
WDLP6_RS12440	COG2918	glutathione biosynthetic process
WDLP6_RS12445	COG2423	ornithine cyclodeaminase activity
WDLP6_RS12460	COG3279	Response regulator of the LytR AlgR family
WDLP6_RS12490	COG2175	clavaminate synthase activity
WDLP6_RS12495	COG1454	alcohol dehydrogenase
WDLP6_RS12505	COG0583	DNA-binding transcription factor activity
WDLP6_RS12510	COG0318	PFAM AMP-dependent synthetase and ligase
WDLP6_RS12515	COG3246	L-lysine catabolic process to acetate
WDLP6_RS12520	COG0179	Fumarylacetoacetate (FAA) hydrolase
WDLP6_RS12535	COG3321	synthase
WDLP6_RS12535	COG1028	Short-chain dehydrogenase reductase Sdr
WDLP6_RS12535	COG0604	alcohol dehydrogenase
WDLP6_RS12580	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
WDLP6_RS12590	COG3279	Response regulator of the LytR AlgR family
WDLP6_RS12595	COG3275	phosphorelay sensor kinase activity
WDLP6_RS12615	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WDLP6_RS12635	COG1968	undecaprenyl-diphosphatase activity
WDLP6_RS12660	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
WDLP6_RS12670	COG3119	arylsulfatase activity
WDLP6_RS12700	COG1289	transmembrane transporter activity
WDLP6_RS12715	COG1045	serine acetyltransferase
WDLP6_RS12720	COG0521	Mo-molybdopterin cofactor biosynthetic process
WDLP6_RS12725	COG3028	Belongs to the UPF0307 family
WDLP6_RS12730	COG0312	modulator of DNA gyrase
WDLP6_RS12740	COG0828	Belongs to the bacterial ribosomal protein bS21 family
WDLP6_RS12745	COG2081	HI0933 family
WDLP6_RS12760	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
WDLP6_RS12765	COG0243	molybdopterin cofactor binding
WDLP6_RS12775	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
WDLP6_RS12785	COG2223	nitrite transmembrane transporter activity
WDLP6_RS12795	COG1116	anion transmembrane transporter activity
WDLP6_RS12800	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WDLP6_RS12805	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
WDLP6_RS12810	COG3707	response regulator
WDLP6_RS12815	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
WDLP6_RS12825	COG0071	Belongs to the small heat shock protein (HSP20) family
WDLP6_RS12830	COG0683	leucine binding
WDLP6_RS12835	COG0436	Aminotransferase
WDLP6_RS12840	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
WDLP6_RS12845	COG1185	polyribonucleotide nucleotidyltransferase activity
WDLP6_RS12855	COG0149	triose-phosphate isomerase activity
WDLP6_RS12870	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WDLP6_RS12875	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WDLP6_RS12880	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WDLP6_RS12885	COG0649	NAD binding
WDLP6_RS12900	COG1034	ATP synthesis coupled electron transport
WDLP6_RS12905	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
WDLP6_RS12910	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WDLP6_RS12920	COG0713	ATP synthesis coupled electron transport
WDLP6_RS12935	COG1007	ATP synthesis coupled electron transport
WDLP6_RS12945	COG0494	nUDIX hydrolase
WDLP6_RS12955	COG1132	(ABC) transporter
WDLP6_RS12960	COG1846	Transcriptional regulator
WDLP6_RS12970	COG1566	PFAM secretion protein HlyD family protein
WDLP6_RS12975	COG2814	Major facilitator Superfamily
WDLP6_RS13025	COG0154	amidase activity
WDLP6_RS13035	COG0477	Major facilitator Superfamily
WDLP6_RS13045	COG1215	transferase activity, transferring glycosyl groups
WDLP6_RS13075	COG3795	YCII-related domain
WDLP6_RS13080	COG0154	amidase activity
WDLP6_RS13095	COG2186	Transcriptional regulator
WDLP6_RS13110	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WDLP6_RS13125	COG0366	Alpha amylase catalytic
WDLP6_RS13145	COG4178	(ABC) transporter
WDLP6_RS13155	COG1136	(ABC) transporter
WDLP6_RS13160	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
WDLP6_RS13170	COG1850	ribulose-bisphosphate carboxylase activity
WDLP6_RS13180	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
WDLP6_RS13185	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
WDLP6_RS13190	COG1609	Transcriptional regulator
WDLP6_RS13200	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
WDLP6_RS13205	COG0586	Pfam SNARE associated Golgi protein
WDLP6_RS13220	COG0860	N-Acetylmuramoyl-L-alanine amidase
WDLP6_RS13225	COG0802	atpase or kinase
WDLP6_RS13230	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
WDLP6_RS13245	COG3181	Tripartite tricarboxylate transporter family receptor
WDLP6_RS13250	COG4974	Belongs to the 'phage' integrase family
WDLP6_RS13260	COG3181	Tripartite tricarboxylate transporter family receptor
WDLP6_RS13265	COG2833	Protein of unknown function (DUF455)
WDLP6_RS13275	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
WDLP6_RS13285	COG0726	polysaccharide deacetylase
WDLP6_RS13295	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WDLP6_RS13295	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
WDLP6_RS13310	COG2076	Multidrug Resistance protein
WDLP6_RS13315	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
WDLP6_RS13320	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
WDLP6_RS13325	COG0148	phosphopyruvate hydratase activity
WDLP6_RS13330	COG2877	3-deoxy-8-phosphooctulonate synthase activity
WDLP6_RS13335	COG0504	CTP synthase activity
WDLP6_RS13340	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
WDLP6_RS13350	COG0756	dUTP diphosphatase activity
WDLP6_RS13360	COG1047	Peptidyl-prolyl cis-trans
WDLP6_RS13365	COG2850	peptidyl-arginine hydroxylation
WDLP6_RS13380	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
WDLP6_RS13385	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
WDLP6_RS13390	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
WDLP6_RS13420	COG0741	lytic transglycosylase activity
WDLP6_RS13450	COG0765	amino acid transport
WDLP6_RS13465	COG1126	abc transporter atp-binding protein
WDLP6_RS13475	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WDLP6_RS13485	COG1609	Transcriptional regulator
WDLP6_RS13495	COG1012	belongs to the aldehyde dehydrogenase family
WDLP6_RS13505	COG1522	sequence-specific DNA binding
WDLP6_RS13535	COG2308	Evidence 4 Homologs of previously reported genes of
WDLP6_RS13580	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
WDLP6_RS13580	COG2273	Hydrolase Family 16
WDLP6_RS13585	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
WDLP6_RS13600	COG3842	ATPase activity
WDLP6_RS13605	COG3842	ATPase activity
WDLP6_RS13615	COG0395	ABC-type sugar transport system, permease component
WDLP6_RS13635	COG2951	lytic endotransglycosylase activity
WDLP6_RS13650	COG0714	Associated with various cellular activities
WDLP6_RS13660	COG1511	domain protein
WDLP6_RS13660	COG3264	Mechanosensitive ion channel
WDLP6_RS13675	COG1960	acyl-CoA dehydrogenase activity
WDLP6_RS13705	COG1294	oxidase, subunit
WDLP6_RS13710	COG1271	oxidase subunit
WDLP6_RS13720	COG4251	negative regulation of phosphorylation
WDLP6_RS13725	COG0784	Response regulator, receiver
WDLP6_RS13730	COG4191	Histidine kinase
WDLP6_RS13730	COG0784	Response regulator, receiver
WDLP6_RS13740	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
WDLP6_RS13755	COG0071	Belongs to the small heat shock protein (HSP20) family
WDLP6_RS13760	COG0477	Major facilitator Superfamily
WDLP6_RS13775	COG0277	FAD linked oxidase domain protein
WDLP6_RS13785	COG1414	Transcriptional regulator
WDLP6_RS13790	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
WDLP6_RS13800	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
WDLP6_RS13845	COG0477	Major facilitator Superfamily
WDLP6_RS13860	COG4941	Belongs to the sigma-70 factor family
WDLP6_RS13870	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
WDLP6_RS13880	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
WDLP6_RS13880	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
WDLP6_RS13885	COG0509	glycine decarboxylation via glycine cleavage system
WDLP6_RS13890	COG0404	The glycine cleavage system catalyzes the degradation of glycine
WDLP6_RS13910	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
WDLP6_RS13915	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WDLP6_RS13920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WDLP6_RS13920	COG2205	protein histidine kinase activity
WDLP6_RS13930	COG1028	Short-chain dehydrogenase reductase Sdr
WDLP6_RS13945	COG0642	Histidine kinase
WDLP6_RS13950	COG0745	RESPONSE REGULATOR receiver
WDLP6_RS13960	COG2194	sulfuric ester hydrolase activity
WDLP6_RS13975	COG4302	ethanolamine ammonia-lyase activity
WDLP6_RS13980	COG4303	Ethanolamine ammonia lyase large subunit
WDLP6_RS13985	COG0545	Peptidyl-prolyl cis-trans isomerase
WDLP6_RS13990	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
WDLP6_RS13995	COG2169	Transcriptional regulator
WDLP6_RS13995	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
WDLP6_RS14035	COG2197	response regulator
WDLP6_RS14080	COG1024	Enoyl-CoA hydratase
WDLP6_RS14090	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
WDLP6_RS14125	COG2197	response regulator
WDLP6_RS14130	COG2197	response regulator
WDLP6_RS14135	COG2909	trisaccharide binding
WDLP6_RS14135	COG2909	trisaccharide binding
WDLP6_RS14145	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WDLP6_RS14155	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
WDLP6_RS14165	COG1132	(ABC) transporter
WDLP6_RS14170	COG3384	dioxygenase
WDLP6_RS14195	COG0587	DNA-directed DNA polymerase activity
WDLP6_RS14215	COG1309	transcriptional regulator
WDLP6_RS14255	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
WDLP6_RS14270	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
WDLP6_RS14275	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
WDLP6_RS14295	COG1028	Short-chain dehydrogenase reductase Sdr
WDLP6_RS14305	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
WDLP6_RS14310	COG0045	succinate-CoA ligase (ADP-forming) activity
WDLP6_RS14315	COG1024	Enoyl-CoA hydratase
WDLP6_RS14330	COG1960	acyl-CoA dehydrogenase activity
WDLP6_RS14335	COG2130	NADP-dependent
WDLP6_RS14340	COG1960	acyl-CoA dehydrogenase activity
WDLP6_RS14350	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WDLP6_RS14355	COG2070	2-Nitropropane dioxygenase
WDLP6_RS14360	COG2188	Transcriptional regulator
WDLP6_RS14375	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
WDLP6_RS14395	COG0625	glutathione transferase activity
WDLP6_RS14455	COG0419	ATPase involved in DNA repair
WDLP6_RS14465	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
WDLP6_RS14490	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
WDLP6_RS14490	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
WDLP6_RS14875	COG0616	signal peptide processing
WDLP6_RS15055	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
WDLP6_RS15065	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
WDLP6_RS15075	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WDLP6_RS15100	COG1028	Short-chain dehydrogenase reductase Sdr
WDLP6_RS15110	COG2267	carboxylic ester hydrolase activity
WDLP6_RS15115	COG1414	Transcriptional regulator
WDLP6_RS15120	COG1028	Short-chain dehydrogenase reductase Sdr
WDLP6_RS15125	COG0028	Belongs to the TPP enzyme family
WDLP6_RS15130	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
WDLP6_RS15135	COG1012	belongs to the aldehyde dehydrogenase family
WDLP6_RS15150	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WDLP6_RS15180	COG0583	DNA-binding transcription factor activity
WDLP6_RS15185	COG2175	clavaminate synthase activity
WDLP6_RS15190	COG3181	Tripartite tricarboxylate transporter family receptor
WDLP6_RS15195	COG1012	belongs to the aldehyde dehydrogenase family
WDLP6_RS15240	COG3278	Belongs to the heme-copper respiratory oxidase family
WDLP6_RS15280	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
WDLP6_RS15300	COG0084	hydrolase, TatD family'
WDLP6_RS15315	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
WDLP6_RS15320	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
WDLP6_RS15330	COG2879	small protein
WDLP6_RS15335	COG1966	Carbon starvation protein
WDLP6_RS15390	COG2183	response to ionizing radiation
WDLP6_RS15395	COG0583	DNA-binding transcription factor activity
WDLP6_RS15420	COG0534	Mate efflux family protein
WDLP6_RS15460	COG0477	Major facilitator Superfamily
WDLP6_RS15465	COG2814	Major facilitator Superfamily
WDLP6_RS15470	COG2814	Major facilitator Superfamily
WDLP6_RS15485	COG3008	intermembrane lipid transfer
WDLP6_RS15485	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
WDLP6_RS15490	COG2995	paraquat-inducible protein a
WDLP6_RS15495	COG2995	paraquat-inducible protein a
WDLP6_RS15500	COG0583	DNA-binding transcription factor activity
WDLP6_RS15505	COG2814	Major facilitator Superfamily
WDLP6_RS15510	COG0667	Aldo Keto reductase
WDLP6_RS15515	COG0745	RESPONSE REGULATOR receiver
WDLP6_RS15520	COG0642	Histidine kinase
WDLP6_RS15530	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
WDLP6_RS15535	COG0583	DNA-binding transcription factor activity
WDLP6_RS15540	COG5507	3-demethylubiquinone-9 3-methyltransferase
WDLP6_RS15560	COG1960	acyl-CoA dehydrogenase activity
WDLP6_RS15565	COG2130	NADP-dependent
WDLP6_RS15585	COG1960	acyl-CoA dehydrogenase activity
WDLP6_RS15590	COG0183	Belongs to the thiolase family
WDLP6_RS15595	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
WDLP6_RS15600	COG1250	3-hydroxyacyl-CoA dehydrogenase
WDLP6_RS15600	COG1024	Enoyl-CoA hydratase
WDLP6_RS15610	COG0411	ABC transporter
WDLP6_RS15620	COG0559	Belongs to the binding-protein-dependent transport system permease family
WDLP6_RS15630	COG0318	PFAM AMP-dependent synthetase and ligase
WDLP6_RS15635	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
WDLP6_RS15640	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
WDLP6_RS15645	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
WDLP6_RS15650	COG2917	probably involved in intracellular septation
WDLP6_RS15660	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
WDLP6_RS15665	COG0047	phosphoribosylformylglycinamidine synthase activity
WDLP6_RS15665	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
WDLP6_RS15670	COG0024	Methionine aminopeptidase
WDLP6_RS15675	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
WDLP6_RS15680	COG2259	Doxx family
WDLP6_RS15685	COG0242	peptide deformylase activity
WDLP6_RS15695	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
WDLP6_RS15705	COG1196	nuclear chromosome segregation
WDLP6_RS15745	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
WDLP6_RS15750	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
WDLP6_RS15755	COG4208	sulfate ABC transporter
WDLP6_RS15765	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
WDLP6_RS15780	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
WDLP6_RS15790	COG1045	serine acetyltransferase
WDLP6_RS15795	COG0583	DNA-binding transcription factor activity
WDLP6_RS15810	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
WDLP6_RS15820	COG0431	NADPH-dependent FMN reductase
WDLP6_RS15825	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
WDLP6_RS15830	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
WDLP6_RS15835	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
WDLP6_RS15835	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WDLP6_RS15845	COG1272	protein, Hemolysin III
WDLP6_RS15855	COG2814	Major facilitator Superfamily
WDLP6_RS15880	COG2895	sulfate adenylyltransferase (ATP) activity
WDLP6_RS15885	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
WDLP6_RS15890	COG0492	ferredoxin-NADP+ reductase activity
WDLP6_RS15895	COG0671	phosphoesterase, PA-phosphatase related
WDLP6_RS15905	COG4654	Cytochrome c, class I
WDLP6_RS15915	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
WDLP6_RS15925	COG0114	fumarate hydratase activity
WDLP6_RS15970	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
WDLP6_RS15975	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
WDLP6_RS15980	COG0740	serine-type endopeptidase activity
WDLP6_RS15985	COG0544	peptidyl-prolyl cis-trans isomerase activity
WDLP6_RS16000	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WDLP6_RS16015	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
WDLP6_RS16025	COG1011	Hydrolase
WDLP6_RS16030	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
WDLP6_RS16070	COG2204	response regulator
WDLP6_RS16110	COG1028	Short-chain dehydrogenase reductase Sdr
WDLP6_RS16115	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
WDLP6_RS16120	COG3181	Tripartite tricarboxylate transporter family receptor
WDLP6_RS16125	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
WDLP6_RS16130	COG0583	DNA-binding transcription factor activity
WDLP6_RS16140	COG1024	Enoyl-CoA hydratase
WDLP6_RS16150	COG1960	acyl-CoA dehydrogenase activity
WDLP6_RS16165	COG1028	Short-chain dehydrogenase reductase Sdr
WDLP6_RS16180	COG0437	4 iron, 4 sulfur cluster binding
WDLP6_RS16220	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
WDLP6_RS16240	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
WDLP6_RS16260	COG3181	Tripartite tricarboxylate transporter family receptor
WDLP6_RS16270	COG0642	Histidine kinase
WDLP6_RS16280	COG2326	polyphosphate kinase activity
WDLP6_RS16290	COG1414	Transcriptional regulator
WDLP6_RS16315	COG0527	aspartate kinase activity
WDLP6_RS16320	COG0037	tRNA processing
WDLP6_RS16325	COG0825	malonyl-CoA metabolic process
WDLP6_RS16335	COG0215	cysteine-tRNA ligase activity
WDLP6_RS16355	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
WDLP6_RS16360	COG3228	Belongs to the MtfA family
WDLP6_RS16375	COG0741	lytic transglycosylase activity
WDLP6_RS16380	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
WDLP6_RS16385	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
WDLP6_RS16445	COG4968	Prepilin-type N-terminal cleavage methylation domain
WDLP6_RS16450	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
WDLP6_RS16450	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
WDLP6_RS16465	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
WDLP6_RS16470	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
WDLP6_RS16475	COG0436	Aminotransferase
WDLP6_RS16480	COG0824	Thioesterase
WDLP6_RS16490	COG0848	biopolymer transport protein
WDLP6_RS16510	COG1741	Belongs to the pirin family
WDLP6_RS16520	COG2259	Doxx family
WDLP6_RS16525	COG1741	Belongs to the pirin family
WDLP6_RS16535	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
WDLP6_RS16535	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WDLP6_RS16540	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
WDLP6_RS16545	COG0220	tRNA (guanine-N7-)-methyltransferase activity
WDLP6_RS16550	COG2863	cytochrome
WDLP6_RS16555	COG2010	Cytochrome c
WDLP6_RS16555	COG1529	Aldehyde oxidase and xanthine dehydrogenase
WDLP6_RS16570	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
WDLP6_RS16580	COG1215	transferase activity, transferring glycosyl groups
WDLP6_RS16585	COG1215	transferase activity, transferring glycosyl groups
WDLP6_RS16590	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
WDLP6_RS16595	COG0457	Tetratricopeptide repeat
WDLP6_RS16610	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
WDLP6_RS16620	COG0840	transmembrane signaling receptor activity
WDLP6_RS16645	COG1619	proteins homologs of microcin C7 resistance protein MccF
WDLP6_RS16675	COG4566	intracellular signal transduction
WDLP6_RS16680	COG4191	Histidine kinase
WDLP6_RS16685	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
WDLP6_RS16690	COG1028	Short-chain dehydrogenase reductase Sdr
WDLP6_RS16695	COG3246	L-lysine catabolic process to acetate
WDLP6_RS16715	COG0559	Belongs to the binding-protein-dependent transport system permease family
WDLP6_RS16735	COG2272	Belongs to the type-B carboxylesterase lipase family
WDLP6_RS16740	COG3181	Tripartite tricarboxylate transporter family receptor
WDLP6_RS16750	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WDLP6_RS16750	COG0045	succinate-CoA ligase (ADP-forming) activity
WDLP6_RS16750	COG1042	CoA-binding domain protein
WDLP6_RS16755	COG2197	response regulator
WDLP6_RS16770	COG0477	Major facilitator Superfamily
WDLP6_RS16775	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
WDLP6_RS16780	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
WDLP6_RS16785	COG1845	cytochrome c oxidase, subunit III
WDLP6_RS16790	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
WDLP6_RS16795	COG3346	SURF1 family
WDLP6_RS16805	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
WDLP6_RS16825	COG0747	negative chemotaxis
WDLP6_RS16830	COG0601	transmembrane transport
WDLP6_RS16835	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WDLP6_RS16840	COG0444	Belongs to the ABC transporter superfamily
WDLP6_RS16845	COG4608	Belongs to the ABC transporter superfamily
WDLP6_RS16850	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
WDLP6_RS16860	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
WDLP6_RS16875	COG1840	ABC-type Fe3 transport system, periplasmic component
WDLP6_RS16885	COG3842	ATPase activity
WDLP6_RS16890	COG1672	PFAM Archaeal ATPase
WDLP6_RS16890	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
WDLP6_RS16895	COG2226	methyltransferase
WDLP6_RS16900	COG0583	DNA-binding transcription factor activity
WDLP6_RS16925	COG4948	Mandelate Racemase Muconate Lactonizing
WDLP6_RS16930	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
WDLP6_RS16940	COG0583	DNA-binding transcription factor activity
WDLP6_RS16950	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WDLP6_RS16960	COG0579	oxidoreductase
WDLP6_RS16995	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
WDLP6_RS17000	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WDLP6_RS17035	COG0235	Class ii aldolase
WDLP6_RS17045	COG1012	belongs to the aldehyde dehydrogenase family
WDLP6_RS17065	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
WDLP6_RS17100	COG0583	DNA-binding transcription factor activity
WDLP6_RS17105	COG3181	Tripartite tricarboxylate transporter family receptor
WDLP6_RS17110	COG1053	succinate dehydrogenase
WDLP6_RS17115	COG1012	belongs to the aldehyde dehydrogenase family
WDLP6_RS17130	COG3842	ATPase activity
WDLP6_RS17165	COG0277	FAD linked oxidase domain protein
WDLP6_RS17170	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
WDLP6_RS17185	COG3181	Tripartite tricarboxylate transporter family receptor
WDLP6_RS17195	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
WDLP6_RS17220	COG0519	Catalyzes the synthesis of GMP from XMP
WDLP6_RS17220	COG0518	GMP synthase (glutamine-hydrolyzing) activity
WDLP6_RS17240	COG2867	negative regulation of translational initiation
WDLP6_RS17245	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
WDLP6_RS17285	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
WDLP6_RS17290	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
WDLP6_RS17295	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
WDLP6_RS17300	COG2251	uridine kinase activity
WDLP6_RS17300	COG0195	Participates in both transcription termination and antitermination
WDLP6_RS17305	COG0779	Required for maturation of 30S ribosomal subunits
WDLP6_RS17310	COG0477	Major facilitator Superfamily
WDLP6_RS17315	COG4172	Belongs to the ABC transporter superfamily
WDLP6_RS17320	COG4239	(ABC) transporter, permease
WDLP6_RS17325	COG4174	ABC transporter (Permease)
WDLP6_RS17340	COG1793	dna ligase
WDLP6_RS17345	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
WDLP6_RS17355	COG1982	Orn Lys Arg decarboxylase major
WDLP6_RS17395	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
WDLP6_RS17415	COG0583	DNA-binding transcription factor activity
WDLP6_RS17420	COG0436	Aminotransferase
WDLP6_RS17430	COG1643	Atp-dependent helicase
WDLP6_RS17435	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
WDLP6_RS17435	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
WDLP6_RS17440	COG0436	Aminotransferase
WDLP6_RS17445	COG2171	N-acyltransferase activity
WDLP6_RS17455	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
WDLP6_RS17460	COG2890	protein-(glutamine-N5) methyltransferase activity
WDLP6_RS17495	COG1053	succinate dehydrogenase
WDLP6_RS17495	COG3976	FMN-binding domain protein
WDLP6_RS17525	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WDLP6_RS17555	COG0745	RESPONSE REGULATOR receiver
WDLP6_RS17560	COG0596	Alpha beta hydrolase
WDLP6_RS17570	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
WDLP6_RS17580	COG2885	chlorophyll binding
WDLP6_RS17585	COG0823	Involved in the tonB-independent uptake of proteins
WDLP6_RS17590	COG1132	(ABC) transporter
WDLP6_RS17595	COG1530	ribonuclease E activity
WDLP6_RS17600	COG0424	maF-like protein
WDLP6_RS17605	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
WDLP6_RS17610	COG0799	negative regulation of ribosome biogenesis
WDLP6_RS17615	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
WDLP6_RS17620	COG0408	coproporphyrinogen oxidase activity
WDLP6_RS17625	COG0151	Belongs to the GarS family
WDLP6_RS17630	COG0217	transcriptional regulatory protein
WDLP6_RS17690	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
WDLP6_RS17705	COG0433	COG0433 Predicted ATPase
WDLP6_RS17710	COG4944	Protein of unknown function (DUF1109)
WDLP6_RS17715	COG1595	DNA-templated transcription, initiation
WDLP6_RS17725	COG3220	belongs to the UPF0276 family
WDLP6_RS17750	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
WDLP6_RS17755	COG1744	ABC transporter substrate-binding protein PnrA-like
WDLP6_RS17775	COG0402	S-adenosylhomocysteine deaminase activity
WDLP6_RS17780	COG2925	Exonuclease
WDLP6_RS17785	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WDLP6_RS17790	COG0542	response to heat
WDLP6_RS17795	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
WDLP6_RS17825	COG0811	peptide transport
WDLP6_RS17830	COG0848	biopolymer transport protein
WDLP6_RS17835	COG1663	tetraacyldisaccharide 4'-kinase activity
WDLP6_RS17840	COG2835	tetraacyldisaccharide 4'-kinase activity
WDLP6_RS17845	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
WDLP6_RS17850	COG0563	adenylate kinase activity
WDLP6_RS17865	COG0252	asparaginase activity
WDLP6_RS17870	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
WDLP6_RS17880	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
WDLP6_RS17885	COG2814	Major facilitator Superfamily
WDLP6_RS17895	COG1250	3-hydroxyacyl-CoA dehydrogenase
WDLP6_RS17900	COG1024	Enoyl-CoA hydratase
WDLP6_RS17925	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
WDLP6_RS17935	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
WDLP6_RS17940	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
WDLP6_RS17945	COG1534	Rna-binding protein
WDLP6_RS17960	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
WDLP6_RS17970	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
WDLP6_RS17975	COG0505	Belongs to the CarA family
WDLP6_RS17980	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
WDLP6_RS17985	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
WDLP6_RS17990	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
WDLP6_RS17995	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
WDLP6_RS18000	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
WDLP6_RS18005	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
WDLP6_RS18020	COG0750	zinc metalloprotease
WDLP6_RS18025	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
WDLP6_RS18030	COG0575	Belongs to the CDS family
WDLP6_RS18035	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
WDLP6_RS18040	COG0233	cytoplasmic translational termination
WDLP6_RS18045	COG0528	UMP kinase activity
WDLP6_RS18050	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
WDLP6_RS18055	COG0052	Belongs to the universal ribosomal protein uS2 family
WDLP6_RS18065	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WDLP6_RS18070	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
WDLP6_RS18070	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
WDLP6_RS18075	COG1028	Short-chain dehydrogenase reductase Sdr
WDLP6_RS18080	COG0557	exoribonuclease II activity
WDLP6_RS18090	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
WDLP6_RS18095	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
WDLP6_RS18110	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
WDLP6_RS18115	COG1028	Short-chain dehydrogenase reductase Sdr
WDLP6_RS18130	COG0745	RESPONSE REGULATOR receiver
WDLP6_RS18135	COG2205	protein histidine kinase activity
WDLP6_RS18140	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
WDLP6_RS18140	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
WDLP6_RS18145	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
WDLP6_RS18145	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
WDLP6_RS18150	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
WDLP6_RS18155	COG0560	Phosphoserine phosphatase
WDLP6_RS18160	COG3181	Tripartite tricarboxylate transporter family receptor
WDLP6_RS18180	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WDLP6_RS18185	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
WDLP6_RS18200	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
WDLP6_RS18205	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
WDLP6_RS18210	COG1492	cobalamin metabolic process
WDLP6_RS18215	COG1538	Outer membrane efflux protein
WDLP6_RS18225	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WDLP6_RS18240	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
WDLP6_RS18250	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
WDLP6_RS18255	COG1120	ATPase activity
WDLP6_RS18260	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WDLP6_RS18265	COG4607	ABC-type enterochelin transport system periplasmic component
WDLP6_RS18275	COG4206	TonB-dependent receptor
WDLP6_RS18290	COG0730	response to heat
WDLP6_RS18300	COG0318	PFAM AMP-dependent synthetase and ligase
WDLP6_RS18320	COG1802	Transcriptional regulator
WDLP6_RS18330	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
WDLP6_RS18335	COG0583	DNA-binding transcription factor activity
WDLP6_RS18340	COG0129	dihydroxy-acid dehydratase activity
WDLP6_RS18350	COG0351	phosphomethylpyrimidine kinase
WDLP6_RS18365	COG2022	thiamine diphosphate biosynthetic process
WDLP6_RS18420	COG1175	transmembrane transport
WDLP6_RS18435	COG0246	Mannitol dehydrogenase
WDLP6_RS18440	COG1028	Short-chain dehydrogenase reductase Sdr
WDLP6_RS18445	COG2207	Transcriptional regulator
WDLP6_RS18445	COG4753	response regulator
WDLP6_RS18450	COG1070	Carbohydrate kinase
WDLP6_RS18465	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WDLP6_RS18470	COG0642	Histidine kinase
WDLP6_RS18475	COG0745	RESPONSE REGULATOR receiver
WDLP6_RS18480	COG1414	Transcriptional regulator
WDLP6_RS18495	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
WDLP6_RS18500	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
WDLP6_RS18505	COG1414	Transcriptional regulator
WDLP6_RS18515	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
WDLP6_RS18520	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
WDLP6_RS18525	COG1183	phosphatidylcholine synthase activity
WDLP6_RS18530	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
WDLP6_RS18535	COG0440	acetolactate synthase activity
WDLP6_RS18540	COG0028	Belongs to the TPP enzyme family
WDLP6_RS18575	COG0347	Belongs to the P(II) protein family
WDLP6_RS18585	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
WDLP6_RS18590	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
WDLP6_RS18615	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WDLP6_RS18670	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
WDLP6_RS18675	COG0746	molybdenum cofactor guanylyltransferase activity
WDLP6_RS18690	COG0328	RNA-DNA hybrid ribonuclease activity
WDLP6_RS18700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WDLP6_RS18705	COG1388	LysM domain
WDLP6_RS18705	COG0741	lytic transglycosylase activity
WDLP6_RS18710	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WDLP6_RS18720	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
WDLP6_RS18730	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
WDLP6_RS18735	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
WDLP6_RS18740	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
WDLP6_RS18825	COG1074	ATP-dependent DNA helicase activity
WDLP6_RS18840	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
WDLP6_RS18845	COG0673	inositol 2-dehydrogenase activity
WDLP6_RS18850	COG0254	rRNA binding
WDLP6_RS18860	COG0534	Mate efflux family protein
WDLP6_RS18865	COG5002	protein histidine kinase activity
WDLP6_RS18880	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
WDLP6_RS18885	COG0581	inorganic phosphate transmembrane transporter activity
WDLP6_RS18890	COG0573	inorganic phosphate transmembrane transporter activity
WDLP6_RS18895	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
WDLP6_RS18910	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
WDLP6_RS18925	COG0625	glutathione transferase activity
WDLP6_RS18965	COG3181	Tripartite tricarboxylate transporter family receptor
WDLP6_RS18970	COG4948	Mandelate Racemase Muconate Lactonizing
WDLP6_RS18980	COG1024	Enoyl-CoA hydratase
WDLP6_RS18985	COG1960	acyl-CoA dehydrogenase activity
WDLP6_RS18990	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WDLP6_RS19010	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
WDLP6_RS19020	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WDLP6_RS19035	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
WDLP6_RS19040	COG0589	response to stress
WDLP6_RS19045	COG3243	poly(R)-hydroxyalkanoic acid synthase
WDLP6_RS19055	COG1028	Short-chain dehydrogenase reductase Sdr
WDLP6_RS19075	COG0784	Response regulator, receiver
WDLP6_RS19075	COG4191	Histidine kinase
WDLP6_RS19115	COG1960	acyl-CoA dehydrogenase activity
WDLP6_RS19120	COG1960	acyl-CoA dehydrogenase activity
WDLP6_RS19145	COG1024	Enoyl-CoA hydratase
WDLP6_RS19155	COG1012	belongs to the aldehyde dehydrogenase family
WDLP6_RS19160	COG0028	Belongs to the TPP enzyme family
WDLP6_RS19195	COG2146	nitrite reductase [NAD(P)H] activity
WDLP6_RS19215	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
WDLP6_RS19220	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
WDLP6_RS19225	COG0045	succinate-CoA ligase (ADP-forming) activity
WDLP6_RS19225	COG1042	CoA-binding domain protein
WDLP6_RS19225	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WDLP6_RS19240	COG0517	IMP dehydrogenase activity
WDLP6_RS19240	COG0516	GMP reductase activity
WDLP6_RS19255	COG2223	nitrite transmembrane transporter activity
WDLP6_RS19260	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
WDLP6_RS19265	COG1140	nitrate reductase beta subunit
WDLP6_RS19270	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
WDLP6_RS19275	COG2181	nitrate reductase activity
WDLP6_RS19305	COG3256	nitric oxide reductase
WDLP6_RS19310	COG1959	2 iron, 2 sulfur cluster binding
WDLP6_RS19315	COG2151	metal-sulfur cluster biosynthetic enzyme
WDLP6_RS19335	COG3162	membrane
WDLP6_RS19340	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
WDLP6_RS19355	COG5002	protein histidine kinase activity
WDLP6_RS19360	COG0745	RESPONSE REGULATOR receiver
WDLP6_RS19365	COG5002	protein histidine kinase activity
WDLP6_RS19365	COG2176	DNA-directed DNA polymerase activity
WDLP6_RS19380	COG1136	(ABC) transporter
WDLP6_RS19390	COG0058	SHG alpha-glucan phosphorylase activity
WDLP6_RS19395	COG0542	response to heat
WDLP6_RS19425	COG0640	Transcriptional regulator
WDLP6_RS19445	COG0459	protein refolding
WDLP6_RS19455	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
WDLP6_RS19460	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WDLP6_RS19490	COG0589	response to stress
WDLP6_RS19495	COG0574	Belongs to the PEP-utilizing enzyme family
WDLP6_RS19495	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
WDLP6_RS19505	COG0071	Belongs to the small heat shock protein (HSP20) family
WDLP6_RS19525	COG0589	response to stress
WDLP6_RS19540	COG0589	response to stress
WDLP6_RS19545	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WDLP6_RS19595	COG0589	response to stress
WDLP6_RS19605	COG0635	Involved in the biosynthesis of porphyrin-containing compound
WDLP6_RS19610	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
WDLP6_RS19635	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
WDLP6_RS19645	COG4670	ketone body catabolic process
WDLP6_RS19650	COG1053	succinate dehydrogenase
WDLP6_RS19655	COG1028	Short-chain dehydrogenase reductase Sdr
WDLP6_RS19675	COG1028	Short-chain dehydrogenase reductase Sdr
WDLP6_RS19685	COG1028	Short-chain dehydrogenase reductase Sdr
WDLP6_RS19695	COG1028	Short-chain dehydrogenase reductase Sdr
WDLP6_RS19700	COG3618	amidohydrolase
WDLP6_RS19710	COG1129	ABC transporter
WDLP6_RS19715	COG0559	Belongs to the binding-protein-dependent transport system permease family
WDLP6_RS19720	COG2186	Transcriptional regulator
WDLP6_RS19725	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WDLP6_RS19740	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WDLP6_RS19790	COG1012	belongs to the aldehyde dehydrogenase family
WDLP6_RS19795	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
WDLP6_RS19805	COG0583	DNA-binding transcription factor activity
WDLP6_RS19815	COG1053	succinate dehydrogenase
WDLP6_RS19820	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
WDLP6_RS19825	COG0066	3-isopropylmalate dehydratase activity
WDLP6_RS19855	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
WDLP6_RS19875	COG0411	ABC transporter
WDLP6_RS19895	COG2982	Protein involved in outer membrane biogenesis
WDLP6_RS19920	COG1024	Enoyl-CoA hydratase
WDLP6_RS19935	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WDLP6_RS19955	COG0589	response to stress
WDLP6_RS19970	COG0456	acetyltransferase
WDLP6_RS19970	COG1846	Transcriptional regulator
WDLP6_RS19975	COG1028	Short-chain dehydrogenase reductase Sdr
WDLP6_RS19995	COG1295	ribonuclease BN
WDLP6_RS20010	COG0667	Aldo Keto reductase
WDLP6_RS20035	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
WDLP6_RS20040	COG1136	(ABC) transporter
WDLP6_RS20055	COG0626	cystathionine gamma-synthase activity
WDLP6_RS20070	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
WDLP6_RS20075	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
WDLP6_RS20085	COG0330	HflC and HflK could
WDLP6_RS20090	COG0330	HflC and HflK could
WDLP6_RS20095	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
WDLP6_RS20100	COG1923	regulation of RNA biosynthetic process
WDLP6_RS20105	COG1160	GTP binding
WDLP6_RS20110	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
WDLP6_RS20120	COG0124	histidyl-tRNA synthetase
WDLP6_RS20125	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
WDLP6_RS20140	COG0820	rRNA (adenine-C2-)-methyltransferase activity
WDLP6_RS20145	COG0105	UTP biosynthetic process
WDLP6_RS20150	COG1187	pseudouridine synthase activity
WDLP6_RS20155	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
WDLP6_RS20160	COG0564	pseudouridine synthase activity
WDLP6_RS20170	COG1199	ATP-dependent helicase activity
WDLP6_RS20190	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
WDLP6_RS20195	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WDLP6_RS20200	COG0508	dehydrogenase complex catalyzes the overall conversion of
WDLP6_RS20205	COG0567	Dehydrogenase, E1 component
WDLP6_RS20220	COG0583	DNA-binding transcription factor activity
WDLP6_RS20225	COG3181	Tripartite tricarboxylate transporter family receptor
WDLP6_RS20235	COG3604	Transcriptional regulator
WDLP6_RS20240	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
WDLP6_RS20240	COG1017	nitric oxide dioxygenase activity
WDLP6_RS20255	COG1360	Flagellar Motor Protein
WDLP6_RS20275	COG0473	3-isopropylmalate dehydrogenase activity
WDLP6_RS20280	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
WDLP6_RS20290	COG2133	pyrroloquinoline quinone binding
WDLP6_RS20295	COG0791	NLP P60 protein
WDLP6_RS20315	COG1129	ABC transporter
WDLP6_RS20330	COG0154	amidase activity
WDLP6_RS20335	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
WDLP6_RS20360	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WDLP6_RS20365	COG0508	dehydrogenase complex catalyzes the overall conversion of
WDLP6_RS20370	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
WDLP6_RS20380	COG4566	intracellular signal transduction
WDLP6_RS20385	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
WDLP6_RS20400	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
WDLP6_RS20405	COG0167	dihydroorotate dehydrogenase activity
WDLP6_RS20420	COG0579	oxidoreductase
WDLP6_RS20445	COG0443	Heat shock 70 kDa protein
WDLP6_RS20460	COG0822	iron-sulfur transferase activity
WDLP6_RS20465	COG1104	cysteine desulfurase activity
WDLP6_RS20470	COG1959	2 iron, 2 sulfur cluster binding
WDLP6_RS20475	COG0556	nucleotide-excision repair
WDLP6_RS20490	COG2878	Part of a membrane complex involved in electron transport
WDLP6_RS20505	COG4770	biotin carboxylase activity
WDLP6_RS20510	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
WDLP6_RS20515	COG1703	isobutyryl-CoA mutase activity
WDLP6_RS20520	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
WDLP6_RS20520	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
WDLP6_RS20525	COG1802	Transcriptional regulator
WDLP6_RS20545	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
WDLP6_RS20555	COG1201	RNA secondary structure unwinding
WDLP6_RS20560	COG2205	protein histidine kinase activity
WDLP6_RS20560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WDLP6_RS20590	COG4651	solute:proton antiporter activity
WDLP6_RS20590	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
WDLP6_RS20595	COG1301	dicarboxylic acid transport
WDLP6_RS20600	COG1028	Short-chain dehydrogenase reductase Sdr
WDLP6_RS20610	COG0183	Belongs to the thiolase family
WDLP6_RS20615	COG3243	poly(R)-hydroxyalkanoic acid synthase
WDLP6_RS20645	COG3045	CreA protein
WDLP6_RS20655	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WDLP6_RS20670	COG0583	DNA-binding transcription factor activity
WDLP6_RS20675	COG3622	Belongs to the hyi family
WDLP6_RS20685	COG3181	Tripartite tricarboxylate transporter family receptor
WDLP6_RS20700	COG1028	Short-chain dehydrogenase reductase Sdr
WDLP6_RS20710	COG2030	dehydratase
WDLP6_RS20720	COG1024	Enoyl-CoA hydratase
WDLP6_RS20725	COG0318	PFAM AMP-dependent synthetase and ligase
WDLP6_RS20730	COG1960	acyl-CoA dehydrogenase activity
WDLP6_RS20740	COG1024	Enoyl-CoA hydratase
WDLP6_RS20760	COG0559	Belongs to the binding-protein-dependent transport system permease family
WDLP6_RS20775	COG2909	trisaccharide binding
WDLP6_RS20780	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WDLP6_RS20790	COG0583	DNA-binding transcription factor activity
WDLP6_RS20795	COG0625	glutathione transferase activity
WDLP6_RS20840	COG0318	PFAM AMP-dependent synthetase and ligase
WDLP6_RS20845	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
WDLP6_RS20850	COG0066	3-isopropylmalate dehydratase activity
WDLP6_RS20860	COG0412	Dienelactone hydrolase
WDLP6_RS20910	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
WDLP6_RS20945	COG0270	DNA (cytosine-5-)-methyltransferase activity
WDLP6_RS20955	COG2948	multi-organism process
WDLP6_RS20985	COG3451	type IV secretory pathway VirB4
WDLP6_RS21000	COG4962	Type ii secretion system protein e
WDLP6_RS21015	COG0583	DNA-binding transcription factor activity
WDLP6_RS21035	COG0601	transmembrane transport
WDLP6_RS21045	COG4172	Belongs to the ABC transporter superfamily
WDLP6_RS21055	COG0242	peptide deformylase activity
WDLP6_RS21070	COG4638	Rieske (2fe-2S)
WDLP6_RS21080	COG1012	belongs to the aldehyde dehydrogenase family
WDLP6_RS21085	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
WDLP6_RS21095	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
WDLP6_RS21115	COG3181	Tripartite tricarboxylate transporter family receptor
WDLP6_RS21145	COG0583	DNA-binding transcription factor activity
WDLP6_RS21155	COG3181	Tripartite tricarboxylate transporter family receptor
WDLP6_RS21175	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
WDLP6_RS21180	COG1396	sequence-specific DNA binding
WDLP6_RS21190	COG4638	Rieske (2fe-2S)
WDLP6_RS21220	COG0596	Alpha beta hydrolase
WDLP6_RS21225	COG2309	aminopeptidase activity
WDLP6_RS21230	COG1335	isochorismatase
WDLP6_RS21280	COG1192	Involved in chromosome partitioning
WDLP6_RS21315	COG5489	Protein of unknown function (DUF736)
WDLP6_RS21320	COG1475	DNA binding
WDLP6_RS21335	COG2003	Belongs to the UPF0758 family
WDLP6_RS21355	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
WDLP6_RS21360	COG1609	Transcriptional regulator
WDLP6_RS21365	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
WDLP6_RS21375	COG1116	anion transmembrane transporter activity
WDLP6_RS21385	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WDLP6_RS21390	COG1024	Enoyl-CoA hydratase
WDLP6_RS21415	COG1012	belongs to the aldehyde dehydrogenase family
WDLP6_RS21440	COG3181	Tripartite tricarboxylate transporter family receptor
WDLP6_RS21450	COG1024	Enoyl-CoA hydratase
WDLP6_RS21465	COG0318	PFAM AMP-dependent synthetase and ligase
WDLP6_RS21480	COG0583	DNA-binding transcription factor activity
WDLP6_RS21485	COG0582	viral genome integration into host DNA
WDLP6_RS21500	COG0776	regulation of translation
WDLP6_RS21510	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
WDLP6_RS21515	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
WDLP6_RS21520	COG0291	Belongs to the bacterial ribosomal protein bL35 family
WDLP6_RS21525	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
WDLP6_RS21530	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
WDLP6_RS21535	COG2224	Isocitrate lyase
WDLP6_RS21560	COG1309	transcriptional regulator
WDLP6_RS21570	COG0673	inositol 2-dehydrogenase activity
WDLP6_RS21625	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
WDLP6_RS21645	COG0659	secondary active sulfate transmembrane transporter activity
WDLP6_RS21665	COG0542	response to heat
WDLP6_RS21685	COG0583	DNA-binding transcription factor activity
WDLP6_RS21690	COG3181	Tripartite tricarboxylate transporter family receptor
WDLP6_RS21695	COG0314	molybdopterin synthase activity
WDLP6_RS21700	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
WDLP6_RS21705	COG0303	'Molybdopterin
WDLP6_RS21710	COG1763	Mo-molybdopterin cofactor biosynthetic process
WDLP6_RS21715	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
WDLP6_RS21725	COG0436	Aminotransferase
WDLP6_RS21735	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
WDLP6_RS21740	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
WDLP6_RS21755	COG0305	Participates in initiation and elongation during chromosome replication
WDLP6_RS21760	COG0359	binds to the 23S rRNA
WDLP6_RS21765	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
WDLP6_RS21770	COG2965	DNA replication, synthesis of RNA primer
WDLP6_RS21775	COG0360	Binds together with S18 to 16S ribosomal RNA
WDLP6_RS21790	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
WDLP6_RS21805	COG3634	alkyl hydroperoxide reductase activity
WDLP6_RS21845	COG3193	protein, possibly involved in utilization of glycolate and propanediol
WDLP6_RS21850	COG0670	Belongs to the BI1 family
WDLP6_RS21855	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
WDLP6_RS21870	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
WDLP6_RS21875	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
WDLP6_RS21880	COG1028	Short-chain dehydrogenase reductase Sdr
WDLP6_RS21880	COG3321	synthase
WDLP6_RS21880	COG0604	alcohol dehydrogenase
WDLP6_RS21920	COG2226	methyltransferase
WDLP6_RS22130	COG0270	DNA (cytosine-5-)-methyltransferase activity
WDLP6_RS22220	COG0484	heat shock protein binding
WDLP6_RS22270	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
WDLP6_RS22285	COG0473	3-isopropylmalate dehydrogenase activity
WDLP6_RS22295	COG4968	Prepilin-type N-terminal cleavage methylation domain
WDLP6_RS22345	COG0322	excinuclease ABC activity
WDLP6_RS22355	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
WDLP6_RS22360	COG1611	Belongs to the LOG family
WDLP6_RS22375	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
WDLP6_RS22385	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
WDLP6_RS22390	COG3237	CsbD-like
WDLP6_RS22400	COG0824	Thioesterase
WDLP6_RS22405	COG0123	including yeast histone deacetylase and acetoin utilization protein
WDLP6_RS22420	COG1959	2 iron, 2 sulfur cluster binding
WDLP6_RS22420	COG1295	ribonuclease BN
WDLP6_RS22425	COG0358	DNA primase activity
WDLP6_RS22435	COG2814	Major facilitator Superfamily
WDLP6_RS22450	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WDLP6_RS22455	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
WDLP6_RS22505	COG1802	Transcriptional regulator
WDLP6_RS22515	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
WDLP6_RS22525	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WDLP6_RS22545	COG1012	belongs to the aldehyde dehydrogenase family
WDLP6_RS22550	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
WDLP6_RS22560	COG2186	Transcriptional regulator
WDLP6_RS22565	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WDLP6_RS22570	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
WDLP6_RS22585	COG2706	6-phosphogluconolactonase activity
WDLP6_RS22590	COG2721	sulfolactate sulfo-lyase activity
WDLP6_RS22600	COG2706	6-phosphogluconolactonase activity
WDLP6_RS22605	COG3181	Tripartite tricarboxylate transporter family receptor
WDLP6_RS22610	COG0688	phosphatidylethanolamine metabolic process
WDLP6_RS22625	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
WDLP6_RS22630	COG0443	Heat shock 70 kDa protein
WDLP6_RS22635	COG0484	heat shock protein binding
WDLP6_RS22640	COG2186	Transcriptional regulator
WDLP6_RS22645	COG0179	Fumarylacetoacetate (FAA) hydrolase
WDLP6_RS22655	COG2766	serine protein kinase
WDLP6_RS22660	COG2718	Belongs to the UPF0229 family
WDLP6_RS22665	COG2719	SpoVR family
WDLP6_RS22670	COG2818	Glycosylase
WDLP6_RS22675	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
WDLP6_RS22680	COG2186	Transcriptional regulator
WDLP6_RS22700	COG0625	glutathione transferase activity
WDLP6_RS22715	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
WDLP6_RS22720	COG3265	gluconokinase activity
WDLP6_RS22735	COG1538	Outer membrane efflux protein
WDLP6_RS22750	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
WDLP6_RS22760	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WDLP6_RS22765	COG0517	IMP dehydrogenase activity
WDLP6_RS22775	COG2267	carboxylic ester hydrolase activity
WDLP6_RS22780	COG0702	epimerase
WDLP6_RS22785	COG3118	belongs to the thioredoxin family
WDLP6_RS22790	COG1295	ribonuclease BN
WDLP6_RS22800	COG0277	FAD linked oxidase domain protein
WDLP6_RS22805	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
WDLP6_RS22850	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WDLP6_RS22855	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WDLP6_RS22865	COG1129	ABC transporter
WDLP6_RS22875	COG1172	Belongs to the binding-protein-dependent transport system permease family
WDLP6_RS22880	COG1879	ABC-type sugar transport system periplasmic component
WDLP6_RS22885	COG1172	Belongs to the binding-protein-dependent transport system permease family
WDLP6_RS22895	COG1024	Enoyl-CoA hydratase
WDLP6_RS22900	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WDLP6_RS22905	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
WDLP6_RS22935	COG0708	Exodeoxyribonuclease III
WDLP6_RS22950	COG3852	Histidine kinase
WDLP6_RS22960	COG0174	glutamine synthetase
WDLP6_RS22965	COG1058	Belongs to the CinA family
WDLP6_RS22965	COG1546	Belongs to the CinA family
WDLP6_RS22990	COG1187	pseudouridine synthase activity
WDLP6_RS23000	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
WDLP6_RS23000	COG4797	methyltransferase
WDLP6_RS23015	COG1262	PFAM Formylglycine-generating sulfatase enzyme
WDLP6_RS23025	COG1063	alcohol dehydrogenase
WDLP6_RS23040	COG0179	Fumarylacetoacetate (FAA) hydrolase
WDLP6_RS23060	COG0583	DNA-binding transcription factor activity
WDLP6_RS23065	COG3971	2-oxopent-4-enoate hydratase activity
WDLP6_RS23075	COG0277	FAD linked oxidase domain protein
WDLP6_RS23080	COG1012	belongs to the aldehyde dehydrogenase family
WDLP6_RS23090	COG0179	Fumarylacetoacetate (FAA) hydrolase
WDLP6_RS23095	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
WDLP6_RS23105	COG1012	belongs to the aldehyde dehydrogenase family
WDLP6_RS23125	COG0583	DNA-binding transcription factor activity
WDLP6_RS23145	COG3119	arylsulfatase activity
WDLP6_RS23160	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
WDLP6_RS23180	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
WDLP6_RS23190	COG0287	Prephenate dehydrogenase
WDLP6_RS23195	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
WDLP6_RS23215	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
WDLP6_RS23240	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
WDLP6_RS23245	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
WDLP6_RS23245	COG2111	Na H antiporter
WDLP6_RS23250	COG1006	Multisubunit Na H antiporter MnhC subunit
WDLP6_RS23255	COG0651	ATP synthesis coupled electron transport
WDLP6_RS23265	COG2212	antiporter activity
WDLP6_RS23270	COG1320	monovalent cation:proton antiporter activity
WDLP6_RS23305	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
WDLP6_RS23305	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
WDLP6_RS23345	COG1063	alcohol dehydrogenase
WDLP6_RS23370	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
WDLP6_RS23370	COG3608	succinylglutamate desuccinylase aspartoacylase
WDLP6_RS23385	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
WDLP6_RS23420	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
WDLP6_RS23425	COG2005	Transcriptional regulator
WDLP6_RS23425	COG3585	molybdate ion transport
WDLP6_RS23440	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
WDLP6_RS23455	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
WDLP6_RS23460	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
WDLP6_RS23465	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WDLP6_RS23470	COG1522	sequence-specific DNA binding
WDLP6_RS23480	COG1122	ATPase activity
WDLP6_RS23530	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
WDLP6_RS23535	COG2151	metal-sulfur cluster biosynthetic enzyme
WDLP6_RS23540	COG3396	Phenylacetate-CoA oxygenase
WDLP6_RS23545	COG3460	Phenylacetate-CoA oxygenase
WDLP6_RS23550	COG3396	Phenylacetate-CoA oxygenase
WDLP6_RS23560	COG2050	protein possibly involved in aromatic compounds catabolism
WDLP6_RS23565	COG1024	Enoyl-CoA hydratase
WDLP6_RS23575	COG1309	transcriptional regulator
WDLP6_RS23580	COG1262	PFAM Formylglycine-generating sulfatase enzyme
WDLP6_RS23600	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
WDLP6_RS23605	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
WDLP6_RS23610	COG0142	geranyltranstransferase activity
WDLP6_RS23615	COG1722	exodeoxyribonuclease VII activity
WDLP6_RS23655	COG3360	Dodecin
WDLP6_RS23670	COG0412	Dienelactone hydrolase
WDLP6_RS23680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WDLP6_RS23710	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
WDLP6_RS23720	COG0210	DNA helicase
WDLP6_RS23730	COG0516	GMP reductase activity
WDLP6_RS23740	COG1028	Short-chain dehydrogenase reductase Sdr
WDLP6_RS23745	COG0183	Belongs to the thiolase family
WDLP6_RS23760	COG0513	Belongs to the DEAD box helicase family
WDLP6_RS23765	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
WDLP6_RS23770	COG0501	Belongs to the peptidase M48B family
WDLP6_RS23775	COG2154	pterin-4-alpha-carbinolamine dehydratase
WDLP6_RS23780	COG1162	GTPase activity
WDLP6_RS23785	COG0297	glycogen (starch) synthase activity
WDLP6_RS23790	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
WDLP6_RS23795	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
WDLP6_RS23800	COG0494	nUDIX hydrolase
WDLP6_RS23805	COG0335	large ribosomal subunit rRNA binding
WDLP6_RS23810	COG0336	Belongs to the RNA methyltransferase TrmD family
WDLP6_RS23815	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
WDLP6_RS23820	COG0228	four-way junction DNA binding
WDLP6_RS23835	COG0306	phosphate transporter
WDLP6_RS23840	COG1392	Phosphate transport regulator
WDLP6_RS23850	COG0617	tRNA 3'-terminal CCA addition
WDLP6_RS23855	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
WDLP6_RS23860	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
WDLP6_RS23870	COG0438	transferase activity, transferring glycosyl groups
WDLP6_RS23890	COG0728	peptidoglycan biosynthetic process
WDLP6_RS23895	COG0268	Binds directly to 16S ribosomal RNA
WDLP6_RS23905	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
WDLP6_RS23910	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
WDLP6_RS23915	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
WDLP6_RS23915	COG0506	proline dehydrogenase activity
WDLP6_RS23915	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
WDLP6_RS23920	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
WDLP6_RS23930	COG3483	tryptophan 2,3-dioxygenase activity
WDLP6_RS23945	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WDLP6_RS23965	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
WDLP6_RS23990	COG2301	Belongs to the HpcH HpaI aldolase family
WDLP6_RS23995	COG4106	trans-aconitate 2-methyltransferase activity
WDLP6_RS24000	COG0039	L-malate dehydrogenase activity
WDLP6_RS24005	COG2188	Transcriptional regulator
WDLP6_RS24020	COG1053	succinate dehydrogenase
WDLP6_RS24025	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
WDLP6_RS24030	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
WDLP6_RS24035	COG0372	Belongs to the citrate synthase family
WDLP6_RS24050	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
WDLP6_RS24055	COG0066	3-isopropylmalate dehydratase activity
WDLP6_RS24060	COG0473	3-isopropylmalate dehydrogenase activity
WDLP6_RS24065	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
WDLP6_RS24075	COG0101	tRNA pseudouridine synthase activity
WDLP6_RS24080	COG0135	phosphoribosylanthranilate isomerase activity
WDLP6_RS24085	COG0133	tryptophan synthase activity
WDLP6_RS24090	COG0159	tryptophan synthase activity
WDLP6_RS24095	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
WDLP6_RS24100	COG0762	integral membrane protein
WDLP6_RS24110	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
WDLP6_RS24115	COG0443	Heat shock 70 kDa protein
WDLP6_RS24120	COG1451	nucleotide metabolic process
WDLP6_RS24125	COG1472	Belongs to the glycosyl hydrolase 3 family
WDLP6_RS24130	COG0736	holo-[acyl-carrier-protein] synthase activity
WDLP6_RS24135	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
WDLP6_RS24140	COG1381	Involved in DNA repair and RecF pathway recombination
WDLP6_RS24145	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
WDLP6_RS24150	COG0571	ribonuclease III activity
WDLP6_RS24165	COG0481	GTPase activity
WDLP6_RS24170	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WDLP6_RS24190	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
WDLP6_RS24195	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
WDLP6_RS24200	COG1028	Short-chain dehydrogenase reductase Sdr
WDLP6_RS24205	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
WDLP6_RS24210	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
WDLP6_RS24215	COG0416	fatty acid biosynthetic process
WDLP6_RS24220	COG0333	Belongs to the bacterial ribosomal protein bL32 family
WDLP6_RS24225	COG1399	metal-binding, possibly nucleic acid-binding protein
WDLP6_RS24230	COG0424	maF-like protein
WDLP6_RS24235	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
WDLP6_RS24240	COG2223	nitrite transmembrane transporter activity
WDLP6_RS24245	COG0616	signal peptide processing
WDLP6_RS24245	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
WDLP6_RS24260	COG0564	pseudouridine synthase activity
WDLP6_RS24265	COG1530	ribonuclease E activity
WDLP6_RS24280	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WDLP6_RS24300	COG0297	glycogen (starch) synthase activity
WDLP6_RS24305	COG3206	protein involved in exopolysaccharide biosynthesis
WDLP6_RS24305	COG0489	protein tyrosine kinase activity
WDLP6_RS24310	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
WDLP6_RS24315	COG1596	polysaccharide export
WDLP6_RS24335	COG0181	hydroxymethylbilane synthase activity
WDLP6_RS24340	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
WDLP6_RS24345	COG0583	DNA-binding transcription factor activity
WDLP6_RS24350	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
WDLP6_RS24370	COG0559	Belongs to the binding-protein-dependent transport system permease family
WDLP6_RS24375	COG0410	ABC transporter
WDLP6_RS24380	COG0411	ABC transporter
WDLP6_RS24390	COG1335	isochorismatase
WDLP6_RS24400	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WDLP6_RS24420	COG1335	isochorismatase
WDLP6_RS24425	COG1942	4-Oxalocrotonate Tautomerase
WDLP6_RS24450	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
WDLP6_RS24455	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WDLP6_RS24465	COG1802	Transcriptional regulator
WDLP6_RS24475	COG0523	cobalamin synthesis protein
WDLP6_RS24485	COG0402	S-adenosylhomocysteine deaminase activity
WDLP6_RS24495	COG4948	Mandelate Racemase Muconate Lactonizing
WDLP6_RS24535	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
WDLP6_RS24535	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
WDLP6_RS24550	COG3022	response to hydroperoxide
WDLP6_RS24555	COG0525	valine-tRNA ligase activity
WDLP6_RS24560	COG1210	Utp--glucose-1-phosphate uridylyltransferase
WDLP6_RS24570	COG0425	Belongs to the sulfur carrier protein TusA family
WDLP6_RS24575	COG2816	NAD+ diphosphatase activity
WDLP6_RS24590	COG0724	RNA recognition motif
WDLP6_RS24605	COG1301	dicarboxylic acid transport
WDLP6_RS24615	COG2197	response regulator
WDLP6_RS24620	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WDLP6_RS24660	COG0559	Belongs to the binding-protein-dependent transport system permease family
WDLP6_RS24665	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
WDLP6_RS24670	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
WDLP6_RS24675	COG1674	ftsk spoiiie
WDLP6_RS24685	COG0492	ferredoxin-NADP+ reductase activity
WDLP6_RS24690	COG0227	Belongs to the bacterial ribosomal protein bL28 family
WDLP6_RS24695	COG0267	Belongs to the bacterial ribosomal protein bL33 family
WDLP6_RS24705	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
WDLP6_RS24705	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
WDLP6_RS24710	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
WDLP6_RS24715	COG1960	acyl-CoA dehydrogenase activity
WDLP6_RS24720	COG1960	acyl-CoA dehydrogenase activity
WDLP6_RS24730	COG1024	Enoyl-CoA hydratase
WDLP6_RS24740	COG0196	riboflavin kinase activity
WDLP6_RS24750	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
WDLP6_RS24755	COG1283	sodium-dependent phosphate transmembrane transporter activity
WDLP6_RS24770	COG0402	S-adenosylhomocysteine deaminase activity
WDLP6_RS24775	COG0402	S-adenosylhomocysteine deaminase activity
WDLP6_RS24780	COG4608	Belongs to the ABC transporter superfamily
WDLP6_RS24785	COG0444	Belongs to the ABC transporter superfamily
WDLP6_RS24795	COG0402	S-adenosylhomocysteine deaminase activity
WDLP6_RS24800	COG0747	negative chemotaxis
WDLP6_RS24810	COG1028	Short-chain dehydrogenase reductase Sdr
WDLP6_RS24840	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
WDLP6_RS24845	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
WDLP6_RS24865	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WDLP6_RS24870	COG0714	Associated with various cellular activities
WDLP6_RS24880	COG2304	oxidoreductase activity
WDLP6_RS24885	COG1028	Short-chain dehydrogenase reductase Sdr
WDLP6_RS24890	COG0583	DNA-binding transcription factor activity
WDLP6_RS24900	COG0445	tRNA wobble uridine modification
WDLP6_RS24910	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
WDLP6_RS24915	COG1737	Transcriptional regulator
WDLP6_RS24940	COG0601	transmembrane transport
WDLP6_RS24950	COG0251	oxidation-reduction process
WDLP6_RS24975	COG3550	peptidyl-serine autophosphorylation
WDLP6_RS24985	COG1136	(ABC) transporter
WDLP6_RS25000	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
WDLP6_RS25030	COG0831	urea catabolic process
WDLP6_RS25040	COG0832	Belongs to the urease beta subunit family
WDLP6_RS25045	COG0804	urea catabolic process
WDLP6_RS25060	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
WDLP6_RS25065	COG0830	nickel cation binding
WDLP6_RS25070	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
WDLP6_RS25080	COG2175	clavaminate synthase activity
WDLP6_RS25085	COG3246	L-lysine catabolic process to acetate
WDLP6_RS25115	COG0028	Belongs to the TPP enzyme family
WDLP6_RS25155	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
WDLP6_RS25165	COG0583	DNA-binding transcription factor activity
WDLP6_RS25170	COG0235	Class ii aldolase
WDLP6_RS25180	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WDLP6_RS25190	COG1024	Enoyl-CoA hydratase
WDLP6_RS25200	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
WDLP6_RS25205	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
WDLP6_RS25225	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
WDLP6_RS25230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
WDLP6_RS25265	COG0635	Involved in the biosynthesis of porphyrin-containing compound
WDLP6_RS25270	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
WDLP6_RS25275	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
WDLP6_RS25285	COG0515	serine threonine protein kinase
WDLP6_RS25285	COG2815	serine threonine protein kinase
WDLP6_RS25290	COG1561	YicC-like family, N-terminal region
WDLP6_RS25295	COG0194	GDP metabolic process
WDLP6_RS25300	COG1758	RNA polymerase activity
WDLP6_RS25305	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
WDLP6_RS25320	COG3971	2-oxopent-4-enoate hydratase activity
WDLP6_RS25325	COG4569	acetaldehyde dehydrogenase (acetylating) activity
WDLP6_RS25330	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
WDLP6_RS25350	COG2936	dipeptidyl-peptidase activity
WDLP6_RS25355	COG3246	L-lysine catabolic process to acetate
WDLP6_RS25360	COG1028	Short-chain dehydrogenase reductase Sdr
WDLP6_RS25375	COG0318	PFAM AMP-dependent synthetase and ligase
WDLP6_RS25425	COG2084	Dehydrogenase
WDLP6_RS25435	COG1420	regulation of RNA biosynthetic process
WDLP6_RS25440	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
WDLP6_RS25445	COG0497	DNA recombination
WDLP6_RS25450	COG1660	Displays ATPase and GTPase activities
WDLP6_RS25460	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
WDLP6_RS25465	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
WDLP6_RS25480	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
WDLP6_RS25490	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
WDLP6_RS25495	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
WDLP6_RS25500	COG0193	aminoacyl-tRNA hydrolase activity
WDLP6_RS25510	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
WDLP6_RS25520	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WDLP6_RS25530	COG4608	Belongs to the ABC transporter superfamily
WDLP6_RS25535	COG0747	negative chemotaxis
WDLP6_RS25540	COG0154	amidase activity
WDLP6_RS25545	COG0583	DNA-binding transcription factor activity
WDLP6_RS25575	COG0588	phosphoglycerate mutase activity
WDLP6_RS25580	COG2267	carboxylic ester hydrolase activity
WDLP6_RS25585	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
WDLP6_RS25590	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
WDLP6_RS25595	COG1984	allophanate hydrolase subunit 2
WDLP6_RS25600	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
WDLP6_RS25605	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
WDLP6_RS25610	COG0742	ribosomal rna small subunit methyltransferase
WDLP6_RS25615	COG0612	Peptidase, M16
WDLP6_RS25620	COG0612	Peptidase, M16
WDLP6_RS25635	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
WDLP6_RS25640	COG1999	signal sequence binding
WDLP6_RS25645	COG0109	protoheme IX farnesyltransferase activity
WDLP6_RS25680	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
WDLP6_RS25685	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
WDLP6_RS25690	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
WDLP6_RS25700	COG2226	methyltransferase
WDLP6_RS25710	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
WDLP6_RS25740	COG1024	Enoyl-CoA hydratase
WDLP6_RS25765	COG1960	acyl-CoA dehydrogenase activity
WDLP6_RS25785	COG2423	ornithine cyclodeaminase activity
WDLP6_RS25790	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WDLP6_RS25820	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
WDLP6_RS25830	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
WDLP6_RS25835	COG2146	nitrite reductase [NAD(P)H] activity
WDLP6_RS25850	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
WDLP6_RS25860	COG1741	Belongs to the pirin family
WDLP6_RS25870	COG3473	Maleate cis-trans isomerase
WDLP6_RS25875	COG0596	Alpha beta hydrolase
WDLP6_RS25880	COG2309	aminopeptidase activity
WDLP6_RS25885	COG1335	isochorismatase
WDLP6_RS25890	COG0183	Belongs to the thiolase family
WDLP6_RS25895	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
WDLP6_RS25905	COG1414	Transcriptional regulator
WDLP6_RS25910	COG0776	regulation of translation
WDLP6_RS25915	COG4948	Mandelate Racemase Muconate Lactonizing
WDLP6_RS25965	COG0318	PFAM AMP-dependent synthetase and ligase
WDLP6_RS25975	COG2814	Major facilitator Superfamily
WDLP6_RS25985	COG1028	Short-chain dehydrogenase reductase Sdr
WDLP6_RS25990	COG2814	Major facilitator Superfamily
WDLP6_RS26005	COG0655	NAD(P)H dehydrogenase (quinone) activity
WDLP6_RS26030	COG3181	Tripartite tricarboxylate transporter family receptor
WDLP6_RS26050	COG0559	Belongs to the binding-protein-dependent transport system permease family
WDLP6_RS26060	COG2124	cytochrome p450
WDLP6_RS26085	COG1028	Short-chain dehydrogenase reductase Sdr
WDLP6_RS26135	COG1028	Short-chain dehydrogenase reductase Sdr
WDLP6_RS26180	COG2124	cytochrome p450
WDLP6_RS26190	COG1446	asparaginase
WDLP6_RS26195	COG4172	Belongs to the ABC transporter superfamily
WDLP6_RS26200	COG0747	negative chemotaxis
WDLP6_RS26210	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WDLP6_RS26240	COG1450	Type ii and iii secretion system protein
WDLP6_RS26265	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
WDLP6_RS26320	COG0583	DNA-binding transcription factor activity
WDLP6_RS26325	COG3485	protocatechuate 3,4-dioxygenase
WDLP6_RS26330	COG3485	protocatechuate 3,4-dioxygenase
WDLP6_RS26340	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
WDLP6_RS26375	COG1051	belongs to the nudix hydrolase family
WDLP6_RS26375	COG1056	cytidyltransferase-related domain
WDLP6_RS26400	COG0540	Belongs to the ATCase OTCase family
WDLP6_RS26405	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
WDLP6_RS26410	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
WDLP6_RS26415	COG1678	Uncharacterized ACR, COG1678
WDLP6_RS26420	COG0415	Belongs to the DNA photolyase family
WDLP6_RS26425	COG0643	Histidine kinase
WDLP6_RS26425	COG0784	Response regulator, receiver
WDLP6_RS26425	COG2198	Histidine kinase
WDLP6_RS26430	COG0840	transmembrane signaling receptor activity
WDLP6_RS26450	COG1773	rubredoxin
WDLP6_RS26460	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
WDLP6_RS26465	COG0138	bifunctional purine biosynthesis protein purh
WDLP6_RS26480	COG1238	metal cluster binding
WDLP6_RS26485	COG0012	GTP binding
WDLP6_RS26490	COG0633	Ferredoxin
WDLP6_RS26490	COG3217	Mosc domain protein beta barrel domain protein
WDLP6_RS26495	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WDLP6_RS26510	COG1024	Enoyl-CoA hydratase
WDLP6_RS26565	COG2255	four-way junction helicase activity
WDLP6_RS26570	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
WDLP6_RS26575	COG2267	carboxylic ester hydrolase activity
WDLP6_RS26580	COG0671	phosphoesterase, PA-phosphatase related
WDLP6_RS26580	COG2453	phosphatase
WDLP6_RS26595	COG4589	Belongs to the CDS family
WDLP6_RS26600	COG0632	four-way junction helicase activity
WDLP6_RS26605	COG1702	phosphate starvation-inducible protein PhoH
WDLP6_RS26610	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
WDLP6_RS26615	COG1490	D-aminoacyl-tRNA deacylase activity
WDLP6_RS26620	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
WDLP6_RS26635	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
WDLP6_RS26640	COG0739	heme binding
WDLP6_RS26645	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
WDLP6_RS26650	COG2814	Major facilitator Superfamily
WDLP6_RS26655	COG0316	Belongs to the HesB IscA family
WDLP6_RS26660	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
WDLP6_RS26665	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
WDLP6_RS26670	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
WDLP6_RS26675	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
WDLP6_RS26690	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
WDLP6_RS26695	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
WDLP6_RS26720	COG0477	Major facilitator Superfamily
WDLP6_RS26745	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
WDLP6_RS26755	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
WDLP6_RS26760	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
WDLP6_RS26765	COG0156	8-amino-7-oxononanoate synthase activity
WDLP6_RS26780	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
WDLP6_RS26790	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
WDLP6_RS26795	COG0318	PFAM AMP-dependent synthetase and ligase
WDLP6_RS26800	COG1960	acyl-CoA dehydrogenase activity
WDLP6_RS26815	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
WDLP6_RS26820	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
WDLP6_RS26835	COG3012	SEC-C Motif Domain Protein
WDLP6_RS26845	COG1960	acyl-CoA dehydrogenase activity
WDLP6_RS26860	COG0183	Belongs to the thiolase family
WDLP6_RS26865	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
WDLP6_RS26870	COG0288	reversible hydration of carbon dioxide
WDLP6_RS26875	COG0789	Transcriptional regulator
WDLP6_RS26890	COG0564	pseudouridine synthase activity
WDLP6_RS26910	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
WDLP6_RS26915	COG0751	glycine-tRNA ligase activity
WDLP6_RS26920	COG0752	glycyl-tRNA synthetase alpha subunit
WDLP6_RS26925	COG0252	asparaginase activity
WDLP6_RS26935	COG0815	Transfers the fatty acyl group on membrane lipoproteins
WDLP6_RS26965	COG3186	Phenylalanine-4-hydroxylase
WDLP6_RS26975	COG0318	PFAM AMP-dependent synthetase and ligase
WDLP6_RS27010	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WDLP6_RS27015	COG0436	Aminotransferase
WDLP6_RS27025	COG0697	spore germination
WDLP6_RS27030	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WDLP6_RS27040	COG1280	lysine exporter protein (LysE YggA)
WDLP6_RS27045	COG0625	glutathione transferase activity
WDLP6_RS27050	COG0384	phenazine biosynthesis protein PhzF
WDLP6_RS27070	COG3485	protocatechuate 3,4-dioxygenase
WDLP6_RS27075	COG3468	outer membrane autotransporter barrel domain protein
WDLP6_RS27085	COG1324	tolerance protein
WDLP6_RS27115	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
WDLP6_RS27125	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
WDLP6_RS27130	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
WDLP6_RS27135	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
WDLP6_RS27150	COG0679	Auxin Efflux Carrier
WDLP6_RS27155	COG0210	DNA helicase
WDLP6_RS27200	COG2186	Transcriptional regulator
WDLP6_RS27250	COG3181	Tripartite tricarboxylate transporter family receptor
WDLP6_RS27260	COG0583	DNA-binding transcription factor activity
WDLP6_RS27315	COG1960	acyl-CoA dehydrogenase activity
WDLP6_RS27320	COG1960	acyl-CoA dehydrogenase activity
WDLP6_RS27325	COG0318	PFAM AMP-dependent synthetase and ligase
WDLP6_RS27330	COG3181	Tripartite tricarboxylate transporter family receptor
WDLP6_RS27340	COG2030	dehydratase
WDLP6_RS27345	COG1024	Enoyl-CoA hydratase
WDLP6_RS27350	COG1028	Short-chain dehydrogenase reductase Sdr
WDLP6_RS27365	COG1024	Enoyl-CoA hydratase
WDLP6_RS27395	COG1802	Transcriptional regulator
WDLP6_RS27400	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
WDLP6_RS27405	COG1116	anion transmembrane transporter activity
WDLP6_RS27410	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WDLP6_RS27450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WDLP6_RS27465	COG0765	amino acid transport
WDLP6_RS27480	COG3119	arylsulfatase activity
WDLP6_RS27510	COG2204	response regulator
WDLP6_RS27515	COG5000	phosphorelay sensor kinase activity
WDLP6_RS27525	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
WDLP6_RS27525	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
WDLP6_RS27535	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
WDLP6_RS27540	COG0085	RNA polymerase activity
WDLP6_RS27545	COG0222	ribosome binding
WDLP6_RS27550	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
WDLP6_RS27555	COG0081	regulation of translation
WDLP6_RS27560	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
WDLP6_RS27570	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
WDLP6_RS27580	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
WDLP6_RS27600	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
WDLP6_RS27605	COG0134	indole-3-glycerol-phosphate synthase activity
WDLP6_RS27610	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
WDLP6_RS27640	COG1028	Short-chain dehydrogenase reductase Sdr
WDLP6_RS27650	COG0318	PFAM AMP-dependent synthetase and ligase
WDLP6_RS27680	COG4638	Rieske (2fe-2S)
WDLP6_RS27695	COG1028	Short-chain dehydrogenase reductase Sdr
WDLP6_RS27700	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
WDLP6_RS27750	COG3321	synthase
WDLP6_RS27750	COG0604	alcohol dehydrogenase
WDLP6_RS27750	COG1028	Short-chain dehydrogenase reductase Sdr
WDLP6_RS27760	COG1250	3-hydroxyacyl-CoA dehydrogenase
WDLP6_RS27770	COG0546	phosphoglycolate phosphatase activity
WDLP6_RS27775	COG2197	response regulator
WDLP6_RS27785	COG3916	Acyl-homoserine-lactone synthase
WDLP6_RS27795	COG2885	chlorophyll binding
WDLP6_RS27795	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
WDLP6_RS27805	COG0745	RESPONSE REGULATOR receiver
WDLP6_RS27845	COG0631	protein serine/threonine phosphatase activity
WDLP6_RS27850	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
WDLP6_RS27870	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
WDLP6_RS27875	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
WDLP6_RS27935	COG0018	arginyl-trna synthetase
WDLP6_RS27945	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
WDLP6_RS27950	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
WDLP6_RS27955	COG1137	ATPase activity
WDLP6_RS27960	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
WDLP6_RS27965	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WDLP6_RS27975	COG2353	YceI-like domain
WDLP6_RS27980	COG3038	cytochrome b561
WDLP6_RS27990	COG4585	Histidine kinase
WDLP6_RS28015	COG0617	tRNA 3'-terminal CCA addition
WDLP6_RS28015	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
WDLP6_RS28015	COG3620	sequence-specific DNA binding
WDLP6_RS28020	COG3179	chitinase
WDLP6_RS28035	COG0653	protein targeting
WDLP6_RS28060	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
WDLP6_RS28075	COG2197	response regulator
WDLP6_RS28080	COG2205	protein histidine kinase activity
WDLP6_RS28080	COG0784	Response regulator, receiver
WDLP6_RS28080	COG2198	Histidine kinase
WDLP6_RS28095	COG1396	sequence-specific DNA binding
WDLP6_RS28100	COG0235	Class ii aldolase
WDLP6_RS28105	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
WDLP6_RS28130	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
WDLP6_RS28140	COG2967	ApaG domain
WDLP6_RS28145	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
WDLP6_RS28175	COG2084	Dehydrogenase
WDLP6_RS28190	COG3181	Tripartite tricarboxylate transporter family receptor
WDLP6_RS28195	COG1609	Transcriptional regulator
WDLP6_RS28235	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WDLP6_RS28240	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
WDLP6_RS28260	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
WDLP6_RS28265	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
WDLP6_RS28305	COG0583	DNA-binding transcription factor activity
WDLP6_RS28320	COG0205	6-phosphofructokinase activity
WDLP6_RS28335	COG2814	Major facilitator Superfamily
WDLP6_RS28340	COG0121	glutamine amidotransferase
WDLP6_RS28360	COG0189	ligase activity
WDLP6_RS28365	COG3135	benzoate transporter
WDLP6_RS28370	COG3158	transport of potassium into the cell
WDLP6_RS28380	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
WDLP6_RS28395	COG0495	leucyl-tRNA aminoacylation
WDLP6_RS28410	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
WDLP6_RS28415	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
WDLP6_RS28420	COG0735	belongs to the Fur family
WDLP6_RS28425	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
WDLP6_RS28435	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
WDLP6_RS28440	COG0210	DNA helicase
WDLP6_RS28445	COG0598	Magnesium transport protein CorA
WDLP6_RS28450	COG0318	PFAM AMP-dependent synthetase and ligase
WDLP6_RS28470	COG0745	RESPONSE REGULATOR receiver
WDLP6_RS28485	COG0482	sulfurtransferase activity
WDLP6_RS28495	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
WDLP6_RS28515	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
WDLP6_RS28525	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
WDLP6_RS28530	COG0438	transferase activity, transferring glycosyl groups
WDLP6_RS28535	COG0438	transferase activity, transferring glycosyl groups
WDLP6_RS28555	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WDLP6_RS28560	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
WDLP6_RS28570	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
WDLP6_RS28575	COG1596	polysaccharide export
WDLP6_RS28580	COG0629	single-stranded DNA binding
WDLP6_RS28605	COG1946	Acyl-CoA thioesterase
WDLP6_RS28615	COG0446	pyridine nucleotide-disulphide oxidoreductase
WDLP6_RS28620	COG3181	Tripartite tricarboxylate transporter family receptor
WDLP6_RS28630	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WDLP6_RS28645	COG0583	DNA-binding transcription factor activity
WDLP6_RS28655	COG3437	response regulator, receiver
WDLP6_RS28655	COG2205	protein histidine kinase activity
WDLP6_RS28655	COG4999	Histidine kinase
WDLP6_RS28655	COG3850	Histidine kinase
WDLP6_RS28665	COG0745	RESPONSE REGULATOR receiver
WDLP6_RS28680	COG0179	Fumarylacetoacetate (FAA) hydrolase
WDLP6_RS28685	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
WDLP6_RS28730	COG0284	orotidine-5'-phosphate decarboxylase activity
WDLP6_RS28745	COG1214	PFAM Peptidase M22, glycoprotease
WDLP6_RS28760	COG0009	L-threonylcarbamoyladenylate synthase
WDLP6_RS28765	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
WDLP6_RS28770	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
WDLP6_RS28775	COG3118	belongs to the thioredoxin family
WDLP6_RS28795	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
WDLP6_RS28805	COG0469	pyruvate kinase activity
WDLP6_RS28810	COG0126	phosphoglycerate kinase activity
WDLP6_RS28815	COG0583	DNA-binding transcription factor activity
WDLP6_RS28830	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WDLP6_RS28850	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
WDLP6_RS28860	COG0242	peptide deformylase activity
WDLP6_RS28870	COG0758	DNA mediated transformation
WDLP6_RS28875	COG2922	Belongs to the Smg family
WDLP6_RS28885	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
WDLP6_RS28890	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
WDLP6_RS28895	COG1862	Preprotein translocase
WDLP6_RS28905	COG1522	sequence-specific DNA binding
WDLP6_RS28910	COG2814	Major facilitator Superfamily
WDLP6_RS28960	COG3622	Belongs to the hyi family
WDLP6_RS28965	COG0235	Class ii aldolase
WDLP6_RS28970	COG3395	kinase activity
WDLP6_RS28975	COG2084	Dehydrogenase
WDLP6_RS28985	COG0513	Belongs to the DEAD box helicase family
WDLP6_RS28990	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
WDLP6_RS28995	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WDLP6_RS29005	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
WDLP6_RS29015	COG0551	DNA topoisomerase type I activity
WDLP6_RS29015	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
WDLP6_RS29025	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
WDLP6_RS29025	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
WDLP6_RS29070	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
WDLP6_RS29075	COG2137	regulation of response to DNA damage stimulus
WDLP6_RS29080	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
WDLP6_RS29085	COG0045	succinate-CoA ligase (ADP-forming) activity
WDLP6_RS29090	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
WDLP6_RS29095	COG0861	Integral membrane protein TerC family
WDLP6_RS29100	COG0631	protein serine/threonine phosphatase activity
WDLP6_RS29120	COG4969	Belongs to the N-Me-Phe pilin family
WDLP6_RS29160	COG0315	cyclic pyranopterin monophosphate synthase activity
WDLP6_RS29165	COG4783	chaperone-mediated protein folding
WDLP6_RS29170	COG1950	PFAM Membrane protein of
WDLP6_RS29180	COG0861	Integral membrane protein TerC family
WDLP6_RS29210	COG4269	membrane
WDLP6_RS29215	COG0625	glutathione transferase activity
WDLP6_RS29230	COG1595	DNA-templated transcription, initiation
WDLP6_RS29235	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
WDLP6_RS29240	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
WDLP6_RS29260	COG4566	intracellular signal transduction
WDLP6_RS29285	COG1522	sequence-specific DNA binding
WDLP6_RS29295	COG1309	transcriptional regulator
WDLP6_RS29300	COG0346	lactoylglutathione lyase activity
WDLP6_RS29345	COG1058	Belongs to the CinA family
WDLP6_RS29345	COG1546	Belongs to the CinA family
WDLP6_RS29350	COG1028	Short-chain dehydrogenase reductase Sdr
WDLP6_RS29365	COG4221	oxidoreductase activity
WDLP6_RS29370	COG1028	Short-chain dehydrogenase reductase Sdr
WDLP6_RS29375	COG1047	Peptidyl-prolyl cis-trans
WDLP6_RS29410	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WDLP6_RS29420	COG0179	Fumarylacetoacetate (FAA) hydrolase
WDLP6_RS29425	COG0667	Aldo Keto reductase
WDLP6_RS29445	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
WDLP6_RS29460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WDLP6_RS29470	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
WDLP6_RS29490	COG1295	ribonuclease BN
WDLP6_RS29490	COG1959	2 iron, 2 sulfur cluster binding
WDLP6_RS29500	COG0445	tRNA wobble uridine modification
WDLP6_RS29565	COG0583	DNA-binding transcription factor activity
WDLP6_RS29570	COG1335	isochorismatase
WDLP6_RS29575	COG1574	metal-dependent hydrolase with the TIM-barrel fold
WDLP6_RS29605	COG0583	DNA-binding transcription factor activity
WDLP6_RS29615	COG1620	l-lactate permease
WDLP6_RS29620	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
WDLP6_RS29625	COG1028	Short-chain dehydrogenase reductase Sdr
WDLP6_RS29650	COG4548	von Willebrand factor, type A
WDLP6_RS29660	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
WDLP6_RS29690	COG1309	transcriptional regulator
WDLP6_RS29710	COG0604	alcohol dehydrogenase
WDLP6_RS29720	COG0583	DNA-binding transcription factor activity
WDLP6_RS29750	COG0583	DNA-binding transcription factor activity
WDLP6_RS29755	COG3485	protocatechuate 3,4-dioxygenase
WDLP6_RS29765	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WDLP6_RS29785	COG1137	ATPase activity
WDLP6_RS29795	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
WDLP6_RS29810	COG3546	catalase activity
WDLP6_RS29815	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
WDLP6_RS29825	COG2204	response regulator
WDLP6_RS29880	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WDLP6_RS29950	COG0514	ATP-dependent DNA helicase (RecQ)
WDLP6_RS30035	COG1809	phosphosulfolactate synthase activity
WDLP6_RS30045	COG1448	Aminotransferase
WDLP6_RS30050	COG3119	arylsulfatase activity
WDLP6_RS30055	COG0583	DNA-binding transcription factor activity
WDLP6_RS30065	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
WDLP6_RS30080	COG3971	2-oxopent-4-enoate hydratase activity
WDLP6_RS30085	COG0179	Fumarylacetoacetate (FAA) hydrolase
WDLP6_RS30105	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
WDLP6_RS30140	COG3237	CsbD-like
WDLP6_RS30150	COG1960	acyl-CoA dehydrogenase activity
WDLP6_RS30155	COG0318	PFAM AMP-dependent synthetase and ligase
WDLP6_RS30180	COG1846	Transcriptional regulator
WDLP6_RS30185	COG0247	lactate metabolic process
WDLP6_RS30185	COG0277	FAD linked oxidase domain protein
WDLP6_RS30190	COG1802	Transcriptional regulator
WDLP6_RS30195	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
WDLP6_RS30215	COG2094	Belongs to the DNA glycosylase MPG family
WDLP6_RS30250	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
WDLP6_RS30270	COG2188	Transcriptional regulator
WDLP6_RS30275	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
WDLP6_RS30280	COG0066	3-isopropylmalate dehydratase activity
WDLP6_RS30295	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
WDLP6_RS30300	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
WDLP6_RS30305	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
WDLP6_RS30335	COG0006	proline dipeptidase activity
WDLP6_RS30355	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
WDLP6_RS30375	COG0281	malic enzyme
WDLP6_RS30375	COG0280	phosphate acetyltransferase
WDLP6_RS30390	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
WDLP6_RS30395	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
WDLP6_RS30400	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
WDLP6_RS30410	COG1385	rRNA (uridine-N3-)-methyltransferase activity
WDLP6_RS30425	COG2814	Major facilitator Superfamily
WDLP6_RS30445	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
WDLP6_RS30450	COG2813	Specifically methylates the guanine in position
WDLP6_RS30450	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
WDLP6_RS30455	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
WDLP6_RS30460	COG2119	membrane
WDLP6_RS30465	COG0724	RNA recognition motif
WDLP6_RS30470	COG0300	oxidoreductase activity
WDLP6_RS30480	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
WDLP6_RS30505	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
WDLP6_RS30510	COG0706	membrane insertase activity
WDLP6_RS30515	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
WDLP6_RS30520	COG0594	ribonuclease P activity
WDLP6_RS30525	COG0230	Belongs to the bacterial ribosomal protein bL34 family
WDLP6_RS30530	COG1192	Involved in chromosome partitioning
WDLP6_RS30545	COG0358	DNA primase activity
WDLP6_RS30610	COG0384	phenazine biosynthesis protein PhzF
WDLP6_RS30740	COG2815	serine threonine protein kinase
WDLP6_RS30740	COG0515	serine threonine protein kinase
WDLP6_RS30825	COG2826	transposase and inactivated derivatives, IS30 family
WDLP6_RS30910	COG3415	Transposase
WDLP6_RS30910	COG2801	Transposase and inactivated derivatives
WDLP6_RS30980	COG2936	dipeptidyl-peptidase activity
WDLP6_RS31015	COG1192	Involved in chromosome partitioning
WDLP6_RS31025	COG1484	DNA-dependent DNA replication
WDLP6_RS31030	COG4584	PFAM Integrase catalytic
WDLP6_RS31145	COG4372	Transposase
WDLP6_RS31230	COG2003	Belongs to the UPF0758 family
WDLP6_RS31320	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
WDLP6_RS31370	COG2948	multi-organism process
WDLP6_RS31430	COG1574	metal-dependent hydrolase with the TIM-barrel fold
WDLP6_RS31485	COG3041	Addiction module toxin RelE StbE family
WDLP6_RS31490	COG3077	Addiction module antitoxin, RelB DinJ family
WDLP6_RS31555	COG1569	PIN domain
WDLP6_RS31560	COG3311	Transcriptional regulator