locus-tag	class	description
G3W91_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
G3W91_RS00030	COG1408	metallophosphoesterase
G3W91_RS00040	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
G3W91_RS00055	COG0392	lysyltransferase activity
G3W91_RS00060	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G3W91_RS00065	COG3568	Endonuclease Exonuclease Phosphatase
G3W91_RS00095	COG1178	ABC-type Fe3 transport system permease component
G3W91_RS00100	COG1176	ABC-type spermidine putrescine transport system, permease component I
G3W91_RS00110	COG3842	ATPase activity
G3W91_RS00115	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G3W91_RS00135	COG4452	Inner membrane protein CreD
G3W91_RS00145	COG2205	protein histidine kinase activity
G3W91_RS00150	COG0745	RESPONSE REGULATOR receiver
G3W91_RS00165	COG2608	mercury ion transmembrane transporter activity
G3W91_RS00175	COG0642	Histidine kinase
G3W91_RS00180	COG1902	pentaerythritol trinitrate reductase activity
G3W91_RS00185	COG0477	Major facilitator Superfamily
G3W91_RS00195	COG5487	UPF0391 membrane protein
G3W91_RS00205	COG0445	tRNA wobble uridine modification
G3W91_RS00210	COG0357	Ribosomal RNA small subunit methyltransferase G
G3W91_RS00220	COG1192	Involved in chromosome partitioning
G3W91_RS00230	COG1475	DNA binding
G3W91_RS00240	COG0277	FAD linked oxidase domain protein
G3W91_RS00245	COG2096	Adenosyltransferase
G3W91_RS00280	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
G3W91_RS00290	COG0850	regulation of cytokinetic process
G3W91_RS00300	COG2233	PERMEase
G3W91_RS00305	COG2050	protein possibly involved in aromatic compounds catabolism
G3W91_RS00320	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
G3W91_RS00360	COG3971	2-oxopent-4-enoate hydratase activity
G3W91_RS00365	COG0154	amidase activity
G3W91_RS00425	COG3246	L-lysine catabolic process to acetate
G3W91_RS00490	COG3246	L-lysine catabolic process to acetate
G3W91_RS00495	COG2175	clavaminate synthase activity
G3W91_RS00505	COG2233	PERMEase
G3W91_RS00525	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
G3W91_RS00530	COG0492	ferredoxin-NADP+ reductase activity
G3W91_RS00535	COG1715	Restriction endonuclease
G3W91_RS00595	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
G3W91_RS00650	COG2814	Major facilitator Superfamily
G3W91_RS00655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G3W91_RS00655	COG2205	protein histidine kinase activity
G3W91_RS00665	COG0484	heat shock protein binding
G3W91_RS00680	COG1028	Short-chain dehydrogenase reductase Sdr
G3W91_RS00700	COG0745	RESPONSE REGULATOR receiver
G3W91_RS00720	COG0740	serine-type endopeptidase activity
G3W91_RS00745	COG1404	Belongs to the peptidase S8 family
G3W91_RS00770	COG3842	ATPase activity
G3W91_RS00775	COG1176	ABC-type spermidine putrescine transport system, permease component I
G3W91_RS00780	COG1177	transmembrane transport
G3W91_RS00795	COG0251	oxidation-reduction process
G3W91_RS00805	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
G3W91_RS00820	COG1228	amidohydrolase
G3W91_RS00845	COG0181	hydroxymethylbilane synthase activity
G3W91_RS00870	COG1215	transferase activity, transferring glycosyl groups
G3W91_RS00875	COG1215	transferase activity, transferring glycosyl groups
G3W91_RS00880	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
G3W91_RS00885	COG0457	Tetratricopeptide repeat
G3W91_RS00890	COG0791	NLP P60 protein
G3W91_RS00900	COG3181	Tripartite tricarboxylate transporter family receptor
G3W91_RS00915	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G3W91_RS00925	COG0583	DNA-binding transcription factor activity
G3W91_RS00930	COG0604	alcohol dehydrogenase
G3W91_RS00940	COG1024	Enoyl-CoA hydratase
G3W91_RS00950	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3W91_RS01055	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
G3W91_RS01065	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G3W91_RS01070	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G3W91_RS01080	COG1752	Esterase of the alpha-beta hydrolase superfamily
G3W91_RS01115	COG3181	Tripartite tricarboxylate transporter family receptor
G3W91_RS01120	COG0006	proline dipeptidase activity
G3W91_RS01130	COG0583	DNA-binding transcription factor activity
G3W91_RS01140	COG0612	Peptidase, M16
G3W91_RS01150	COG1902	pentaerythritol trinitrate reductase activity
G3W91_RS01155	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
G3W91_RS01155	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
G3W91_RS01190	COG3459	Glycosyltransferase 36 associated
G3W91_RS01220	COG4221	oxidoreductase activity
G3W91_RS01225	COG0697	spore germination
G3W91_RS01230	COG0583	DNA-binding transcription factor activity
G3W91_RS01240	COG0583	DNA-binding transcription factor activity
G3W91_RS01250	COG1024	Enoyl-CoA hydratase
G3W91_RS01265	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3W91_RS01285	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G3W91_RS01300	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G3W91_RS01305	COG1950	PFAM Membrane protein of
G3W91_RS01330	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G3W91_RS01335	COG0450	alkyl hydroperoxide reductase
G3W91_RS01345	COG0583	DNA-binding transcription factor activity
G3W91_RS01350	COG1960	acyl-CoA dehydrogenase activity
G3W91_RS01355	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W91_RS01375	COG4221	oxidoreductase activity
G3W91_RS01395	COG3321	synthase
G3W91_RS01395	COG0604	alcohol dehydrogenase
G3W91_RS01395	COG1028	Short-chain dehydrogenase reductase Sdr
G3W91_RS01400	COG3246	L-lysine catabolic process to acetate
G3W91_RS01410	COG3485	protocatechuate 3,4-dioxygenase
G3W91_RS01415	COG1609	Transcriptional regulator
G3W91_RS01425	COG0515	serine threonine protein kinase
G3W91_RS01445	COG0583	DNA-binding transcription factor activity
G3W91_RS01450	COG2066	Belongs to the glutaminase family
G3W91_RS01455	COG0697	spore germination
G3W91_RS01465	COG0402	S-adenosylhomocysteine deaminase activity
G3W91_RS01480	COG2188	Transcriptional regulator
G3W91_RS01485	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G3W91_RS01490	COG0700	Nucleoside recognition
G3W91_RS01495	COG3540	Alkaline phosphatase
G3W91_RS01515	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
G3W91_RS01520	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
G3W91_RS01525	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G3W91_RS01565	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3W91_RS01580	COG2986	histidine ammonia-lyase
G3W91_RS01580	COG2986	histidine ammonia-lyase
G3W91_RS01585	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
G3W91_RS01610	COG1228	amidohydrolase
G3W91_RS01650	COG0583	DNA-binding transcription factor activity
G3W91_RS01660	COG1410	methionine synthase
G3W91_RS01660	COG0646	methionine synthase
G3W91_RS01680	COG1131	(ABC) transporter
G3W91_RS01680	COG0842	Transport permease protein
G3W91_RS01680	COG1716	ATPase activity
G3W91_RS01690	COG1309	transcriptional regulator
G3W91_RS01735	COG0411	ABC transporter
G3W91_RS01745	COG1335	isochorismatase
G3W91_RS01750	COG2080	2 iron, 2 sulfur cluster binding
G3W91_RS01755	COG2010	Cytochrome c
G3W91_RS01755	COG1529	Aldehyde oxidase and xanthine dehydrogenase
G3W91_RS01785	COG0606	chelatase, subunit chli
G3W91_RS01795	COG0347	Belongs to the P(II) protein family
G3W91_RS01800	COG0004	ammonium transporteR
G3W91_RS01810	COG0277	FAD linked oxidase domain protein
G3W91_RS01815	COG0247	lactate metabolic process
G3W91_RS01830	COG0386	Belongs to the glutathione peroxidase family
G3W91_RS01845	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
G3W91_RS01855	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
G3W91_RS01865	COG3181	Tripartite tricarboxylate transporter family receptor
G3W91_RS01870	COG0129	dihydroxy-acid dehydratase activity
G3W91_RS01880	COG3971	2-oxopent-4-enoate hydratase activity
G3W91_RS01890	COG3384	dioxygenase
G3W91_RS01895	COG1012	belongs to the aldehyde dehydrogenase family
G3W91_RS01915	COG1846	Transcriptional regulator
G3W91_RS01930	COG2974	May be involved in recombination
G3W91_RS01960	COG0745	RESPONSE REGULATOR receiver
G3W91_RS01965	COG0579	oxidoreductase
G3W91_RS01975	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G3W91_RS01990	COG2211	Major facilitator Superfamily
G3W91_RS01995	COG0501	Belongs to the peptidase M48B family
G3W91_RS02000	COG4221	oxidoreductase activity
G3W91_RS02005	COG0583	DNA-binding transcription factor activity
G3W91_RS02010	COG1335	isochorismatase
G3W91_RS02020	COG1574	metal-dependent hydrolase with the TIM-barrel fold
G3W91_RS02040	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G3W91_RS02045	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3W91_RS02085	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G3W91_RS02090	COG1335	isochorismatase
G3W91_RS02100	COG1335	isochorismatase
G3W91_RS02120	COG0583	DNA-binding transcription factor activity
G3W91_RS02125	COG0708	Exodeoxyribonuclease III
G3W91_RS02130	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
G3W91_RS02140	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
G3W91_RS02145	COG0154	amidase activity
G3W91_RS02150	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
G3W91_RS02155	COG1077	Cell shape determining protein MreB Mrl
G3W91_RS02170	COG0768	penicillin binding
G3W91_RS02180	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G3W91_RS02185	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
G3W91_RS02205	COG2095	MarC family integral membrane protein
G3W91_RS02210	COG1028	Short-chain dehydrogenase reductase Sdr
G3W91_RS02220	COG0412	Dienelactone hydrolase
G3W91_RS02230	COG0583	DNA-binding transcription factor activity
G3W91_RS02240	COG0598	Magnesium transport protein CorA
G3W91_RS02260	COG3411	Ferredoxin
G3W91_RS02265	COG2945	thiolester hydrolase activity
G3W91_RS02270	COG1686	Belongs to the peptidase S11 family
G3W91_RS02275	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
G3W91_RS02280	COG0049	tRNA binding
G3W91_RS02285	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
G3W91_RS02290	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
G3W91_RS02295	COG0051	transcription antitermination factor activity, RNA binding
G3W91_RS02310	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
G3W91_RS02315	COG0088	Forms part of the polypeptide exit tunnel
G3W91_RS02320	COG0089	rRNA binding
G3W91_RS02325	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
G3W91_RS02330	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
G3W91_RS02335	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
G3W91_RS02340	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
G3W91_RS02345	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
G3W91_RS02350	COG0255	Belongs to the universal ribosomal protein uL29 family
G3W91_RS02355	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
G3W91_RS02360	COG0678	peroxiredoxin activity
G3W91_RS02365	COG0456	acetyltransferase
G3W91_RS02375	COG3909	cytochrome
G3W91_RS02380	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G3W91_RS02400	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
G3W91_RS02405	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
G3W91_RS02425	COG4251	negative regulation of phosphorylation
G3W91_RS02430	COG2130	NADP-dependent
G3W91_RS02445	COG2188	Transcriptional regulator
G3W91_RS02460	COG0114	fumarate hydratase activity
G3W91_RS02465	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
G3W91_RS02470	COG0318	PFAM AMP-dependent synthetase and ligase
G3W91_RS02475	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
G3W91_RS02480	COG0321	lipoyl(octanoyl) transferase activity
G3W91_RS02485	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
G3W91_RS02495	COG0356	it plays a direct role in the translocation of protons across the membrane
G3W91_RS02505	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
G3W91_RS02510	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
G3W91_RS02515	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
G3W91_RS02520	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
G3W91_RS02525	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
G3W91_RS02530	COG0355	proton-transporting ATP synthase activity, rotational mechanism
G3W91_RS02540	COG1129	ABC transporter
G3W91_RS02545	COG1172	Belongs to the binding-protein-dependent transport system permease family
G3W91_RS02550	COG1879	ABC-type sugar transport system periplasmic component
G3W91_RS02555	COG0673	inositol 2-dehydrogenase activity
G3W91_RS02600	COG1793	dna ligase
G3W91_RS02600	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
G3W91_RS02605	COG1793	dna ligase
G3W91_RS02610	COG1201	RNA secondary structure unwinding
G3W91_RS02670	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G3W91_RS02680	COG1309	transcriptional regulator
G3W91_RS02690	COG0582	viral genome integration into host DNA
G3W91_RS02735	COG1002	Type II restriction enzyme, methylase subunits
G3W91_RS02885	COG2801	Transposase and inactivated derivatives
G3W91_RS02890	COG2801	Transposase and inactivated derivatives
G3W91_RS02920	COG0469	pyruvate kinase activity
G3W91_RS02930	COG2084	Dehydrogenase
G3W91_RS02935	COG0477	Major facilitator Superfamily
G3W91_RS02945	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
G3W91_RS02980	COG0477	Major facilitator Superfamily
G3W91_RS03010	COG3386	PFAM SMP-30 Gluconolaconase
G3W91_RS03015	COG1028	Short-chain dehydrogenase reductase Sdr
G3W91_RS03025	COG1012	belongs to the aldehyde dehydrogenase family
G3W91_RS03030	COG1879	ABC-type sugar transport system periplasmic component
G3W91_RS03035	COG4213	ABC transporter substrate-binding protein
G3W91_RS03045	COG4214	carbohydrate transport
G3W91_RS03050	COG1129	ABC transporter
G3W91_RS03055	COG1172	Belongs to the binding-protein-dependent transport system permease family
G3W91_RS03060	COG1172	Belongs to the binding-protein-dependent transport system permease family
G3W91_RS03085	COG0792	nuclease activity
G3W91_RS03090	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
G3W91_RS03100	COG2084	Dehydrogenase
G3W91_RS03130	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
G3W91_RS03160	COG3639	organic phosphonate transmembrane transporter activity
G3W91_RS03165	COG3639	organic phosphonate transmembrane transporter activity
G3W91_RS03170	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
G3W91_RS03175	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
G3W91_RS03180	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G3W91_RS03190	COG0709	Synthesizes selenophosphate from selenide and ATP
G3W91_RS03210	COG1309	transcriptional regulator
G3W91_RS03235	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
G3W91_RS03235	COG2124	cytochrome p450
G3W91_RS03250	COG0318	PFAM AMP-dependent synthetase and ligase
G3W91_RS03255	COG0439	Biotin carboxylase
G3W91_RS03270	COG1346	cytolysis
G3W91_RS03275	COG1380	Effector of murein hydrolase LrgA
G3W91_RS03280	COG0277	FAD linked oxidase domain protein
G3W91_RS03325	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G3W91_RS03375	COG1473	amidohydrolase
G3W91_RS03390	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G3W91_RS03445	COG0343	queuine tRNA-ribosyltransferase activity
G3W91_RS03450	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
G3W91_RS03455	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
G3W91_RS03465	COG0783	Belongs to the Dps family
G3W91_RS03470	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
G3W91_RS03485	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
G3W91_RS03490	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
G3W91_RS03495	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
G3W91_RS03500	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
G3W91_RS03505	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
G3W91_RS03510	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
G3W91_RS03515	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
G3W91_RS03520	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
G3W91_RS03525	COG1841	ribosomal large subunit assembly
G3W91_RS03530	COG0200	Binds to the 23S rRNA
G3W91_RS03535	COG0201	protein transport
G3W91_RS03540	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
G3W91_RS03545	COG0257	Belongs to the bacterial ribosomal protein bL36 family
G3W91_RS03550	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
G3W91_RS03555	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
G3W91_RS03560	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
G3W91_RS03565	COG0202	RNA polymerase activity
G3W91_RS03570	COG0203	ribosomal protein L17
G3W91_RS03590	COG1960	acyl-CoA dehydrogenase activity
G3W91_RS03595	COG1024	Enoyl-CoA hydratase
G3W91_RS03610	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G3W91_RS03635	COG0583	DNA-binding transcription factor activity
G3W91_RS03640	COG1028	Short-chain dehydrogenase reductase Sdr
G3W91_RS03650	COG0022	dehydrogenase e1 component
G3W91_RS03655	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
G3W91_RS03695	COG4213	ABC transporter substrate-binding protein
G3W91_RS03700	COG4214	carbohydrate transport
G3W91_RS03705	COG1129	ABC transporter
G3W91_RS03720	COG0402	S-adenosylhomocysteine deaminase activity
G3W91_RS03725	COG0693	protein deglycase activity
G3W91_RS03760	COG1022	Amp-dependent synthetase and ligase
G3W91_RS03765	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G3W91_RS03775	COG1028	Short-chain dehydrogenase reductase Sdr
G3W91_RS03795	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
G3W91_RS03800	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
G3W91_RS03805	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
G3W91_RS03810	COG2205	protein histidine kinase activity
G3W91_RS03815	COG0745	RESPONSE REGULATOR receiver
G3W91_RS03825	COG1187	pseudouridine synthase activity
G3W91_RS03830	COG0745	RESPONSE REGULATOR receiver
G3W91_RS03890	COG0326	Molecular chaperone. Has ATPase activity
G3W91_RS03895	COG2124	cytochrome p450
G3W91_RS03900	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W91_RS03905	COG3181	Tripartite tricarboxylate transporter family receptor
G3W91_RS03910	COG1960	acyl-CoA dehydrogenase activity
G3W91_RS03915	COG0583	DNA-binding transcription factor activity
G3W91_RS03920	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
G3W91_RS03930	COG1764	response to oxidative stress
G3W91_RS03935	COG1846	Transcriptional regulator
G3W91_RS03945	COG1250	3-hydroxyacyl-CoA dehydrogenase
G3W91_RS03950	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
G3W91_RS03970	COG0559	Belongs to the binding-protein-dependent transport system permease family
G3W91_RS04050	COG2268	Band 7 protein
G3W91_RS04055	COG5564	TIM-barrel signal transduction protein
G3W91_RS04060	COG5441	Belongs to the UPF0261 family
G3W91_RS04085	COG1228	amidohydrolase
G3W91_RS04090	COG1228	amidohydrolase
G3W91_RS04095	COG0596	Alpha beta hydrolase
G3W91_RS04100	COG0179	Fumarylacetoacetate (FAA) hydrolase
G3W91_RS04120	COG2205	protein histidine kinase activity
G3W91_RS04130	COG0596	Alpha beta hydrolase
G3W91_RS04155	COG1960	acyl-CoA dehydrogenase activity
G3W91_RS04165	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
G3W91_RS04170	COG1652	LysM domain
G3W91_RS04180	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
G3W91_RS04220	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G3W91_RS04225	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
G3W91_RS04235	COG0640	Transcriptional regulator
G3W91_RS04250	COG0625	glutathione transferase activity
G3W91_RS04255	COG0583	DNA-binding transcription factor activity
G3W91_RS04260	COG1131	(ABC) transporter
G3W91_RS04265	COG0842	Transport permease protein
G3W91_RS04270	COG2733	membrane
G3W91_RS04280	COG1473	amidohydrolase
G3W91_RS04295	COG0243	molybdopterin cofactor binding
G3W91_RS04385	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
G3W91_RS04390	COG4106	trans-aconitate 2-methyltransferase activity
G3W91_RS04405	COG2076	Multidrug Resistance protein
G3W91_RS04415	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
G3W91_RS04420	COG1086	Polysaccharide biosynthesis protein
G3W91_RS04460	COG0463	Glycosyl transferase, family 2
G3W91_RS04485	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
G3W91_RS04495	COG0275	rRNA processing
G3W91_RS04500	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
G3W91_RS04515	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G3W91_RS04535	COG0662	Cupin 2, conserved barrel domain protein
G3W91_RS04535	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
G3W91_RS04540	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
G3W91_RS04540	COG2755	lipolytic protein G-D-S-L family
G3W91_RS04545	COG0438	transferase activity, transferring glycosyl groups
G3W91_RS04545	COG1216	Glycosyl transferase, family 2
G3W91_RS04550	COG1215	transferase activity, transferring glycosyl groups
G3W91_RS04565	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
G3W91_RS04575	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G3W91_RS04580	COG1309	transcriptional regulator
G3W91_RS04585	COG0753	catalase activity
G3W91_RS04605	COG1280	lysine exporter protein (LysE YggA)
G3W91_RS04610	COG1028	Short-chain dehydrogenase reductase Sdr
G3W91_RS04620	COG0628	permease
G3W91_RS04635	COG0861	Integral membrane protein TerC family
G3W91_RS04675	COG2084	Dehydrogenase
G3W91_RS04680	COG0583	DNA-binding transcription factor activity
G3W91_RS04685	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
G3W91_RS04695	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
G3W91_RS04745	COG0671	phosphoesterase, PA-phosphatase related
G3W91_RS04755	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
G3W91_RS04760	COG5002	protein histidine kinase activity
G3W91_RS04765	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
G3W91_RS04770	COG2721	sulfolactate sulfo-lyase activity
G3W91_RS04775	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
G3W91_RS04785	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G3W91_RS04790	COG2186	Transcriptional regulator
G3W91_RS04795	COG1028	Short-chain dehydrogenase reductase Sdr
G3W91_RS04800	COG1028	Short-chain dehydrogenase reductase Sdr
G3W91_RS04805	COG0179	Fumarylacetoacetate (FAA) hydrolase
G3W91_RS04820	COG4191	Histidine kinase
G3W91_RS04825	COG4566	intracellular signal transduction
G3W91_RS04845	COG2076	Multidrug Resistance protein
G3W91_RS04850	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
G3W91_RS04865	COG1960	acyl-CoA dehydrogenase activity
G3W91_RS04875	COG1250	3-hydroxyacyl-CoA dehydrogenase
G3W91_RS04875	COG1024	Enoyl-CoA hydratase
G3W91_RS04880	COG0183	Belongs to the thiolase family
G3W91_RS04895	COG1024	Enoyl-CoA hydratase
G3W91_RS04905	COG1607	acyl-coa hydrolase
G3W91_RS04910	COG5265	(ABC) transporter
G3W91_RS04915	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G3W91_RS04925	COG0559	Belongs to the binding-protein-dependent transport system permease family
G3W91_RS04930	COG1172	Belongs to the binding-protein-dependent transport system permease family
G3W91_RS04935	COG0411	ABC transporter
G3W91_RS04950	COG3473	Maleate cis-trans isomerase
G3W91_RS04955	COG0596	Alpha beta hydrolase
G3W91_RS04960	COG2309	aminopeptidase activity
G3W91_RS04965	COG1335	isochorismatase
G3W91_RS04975	COG0583	DNA-binding transcription factor activity
G3W91_RS04985	COG0765	amino acid transport
G3W91_RS04990	COG0765	amino acid transport
G3W91_RS04995	COG1126	abc transporter atp-binding protein
G3W91_RS05000	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G3W91_RS05020	COG2271	Major facilitator Superfamily
G3W91_RS05055	COG3181	Tripartite tricarboxylate transporter family receptor
G3W91_RS05060	COG0318	PFAM AMP-dependent synthetase and ligase
G3W91_RS05065	COG1960	acyl-CoA dehydrogenase activity
G3W91_RS05070	COG1960	acyl-CoA dehydrogenase activity
G3W91_RS05075	COG0183	Belongs to the thiolase family
G3W91_RS05085	COG0583	DNA-binding transcription factor activity
G3W91_RS05090	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
G3W91_RS05105	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
G3W91_RS05110	COG3181	Tripartite tricarboxylate transporter family receptor
G3W91_RS05135	COG0418	dihydroorotase activity
G3W91_RS05175	COG1414	Transcriptional regulator
G3W91_RS05180	COG0501	Belongs to the peptidase M48B family
G3W91_RS05185	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
G3W91_RS05200	COG2226	methyltransferase
G3W91_RS05210	COG1187	pseudouridine synthase activity
G3W91_RS05215	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G3W91_RS05220	COG3181	Tripartite tricarboxylate transporter family receptor
G3W91_RS05245	COG0330	HflC and HflK could
G3W91_RS05250	COG0598	Magnesium transport protein CorA
G3W91_RS05265	COG3181	Tripartite tricarboxylate transporter family receptor
G3W91_RS05285	COG3181	Tripartite tricarboxylate transporter family receptor
G3W91_RS05295	COG2072	flavoprotein involved in K transport
G3W91_RS05305	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
G3W91_RS05320	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
G3W91_RS05325	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
G3W91_RS05330	COG0523	cobalamin synthesis protein
G3W91_RS05345	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
G3W91_RS05350	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
G3W91_RS05355	COG2001	Belongs to the MraZ family
G3W91_RS05360	COG0275	rRNA processing
G3W91_RS05375	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
G3W91_RS05380	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
G3W91_RS05385	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
G3W91_RS05390	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
G3W91_RS05395	COG0772	Belongs to the SEDS family
G3W91_RS05400	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
G3W91_RS05405	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
G3W91_RS05410	COG1181	Belongs to the D-alanine--D-alanine ligase family
G3W91_RS05415	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
G3W91_RS05425	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
G3W91_RS05430	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
G3W91_RS05435	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G3W91_RS05450	COG1595	DNA-templated transcription, initiation
G3W91_RS05470	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
G3W91_RS05475	COG0575	Belongs to the CDS family
G3W91_RS05495	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
G3W91_RS05510	COG3150	esterase
G3W91_RS05515	COG0772	Belongs to the SEDS family
G3W91_RS05520	COG0312	modulator of DNA gyrase
G3W91_RS05525	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
G3W91_RS05535	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
G3W91_RS05545	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G3W91_RS05550	COG0511	ligase activity, forming carbon-carbon bonds
G3W91_RS05555	COG0439	Biotin carboxylase
G3W91_RS05560	COG2264	protein methyltransferase activity
G3W91_RS05570	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G3W91_RS05580	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G3W91_RS05615	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
G3W91_RS05620	COG2943	transferase activity, transferring hexosyl groups
G3W91_RS05620	COG3416	Protein conserved in bacteria
G3W91_RS05630	COG2204	response regulator
G3W91_RS05640	COG2205	protein histidine kinase activity
G3W91_RS05645	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
G3W91_RS05655	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G3W91_RS05660	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G3W91_RS05705	COG0037	tRNA processing
G3W91_RS05715	COG1028	Short-chain dehydrogenase reductase Sdr
G3W91_RS05755	COG1028	Short-chain dehydrogenase reductase Sdr
G3W91_RS05760	COG0583	DNA-binding transcription factor activity
G3W91_RS05775	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
G3W91_RS05780	COG3387	PFAM Glycoside hydrolase 15-related
G3W91_RS05790	COG0617	tRNA 3'-terminal CCA addition
G3W91_RS05800	COG1285	pathogenesis
G3W91_RS05805	COG0739	heme binding
G3W91_RS05805	COG0741	lytic transglycosylase activity
G3W91_RS05805	COG1196	nuclear chromosome segregation
G3W91_RS05810	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
G3W91_RS05815	COG0583	DNA-binding transcription factor activity
G3W91_RS05830	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G3W91_RS05850	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
G3W91_RS05855	COG1522	sequence-specific DNA binding
G3W91_RS05870	COG2188	Transcriptional regulator
G3W91_RS05920	COG0318	PFAM AMP-dependent synthetase and ligase
G3W91_RS05955	COG2828	Protein conserved in bacteria
G3W91_RS05960	COG1024	Enoyl-CoA hydratase
G3W91_RS05985	COG1042	CoA-binding domain protein
G3W91_RS05985	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G3W91_RS05985	COG0045	succinate-CoA ligase (ADP-forming) activity
G3W91_RS05995	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
G3W91_RS06000	COG0066	3-isopropylmalate dehydratase activity
G3W91_RS06095	COG0583	DNA-binding transcription factor activity
G3W91_RS06100	COG0436	Aminotransferase
G3W91_RS06110	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G3W91_RS06120	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
G3W91_RS06140	COG0436	Aminotransferase
G3W91_RS06145	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G3W91_RS06150	COG3278	Belongs to the heme-copper respiratory oxidase family
G3W91_RS06160	COG2010	Cytochrome c
G3W91_RS06230	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G3W91_RS06240	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G3W91_RS06255	COG1942	4-Oxalocrotonate Tautomerase
G3W91_RS06270	COG1414	Transcriptional regulator
G3W91_RS06330	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G3W91_RS06335	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G3W91_RS06350	COG3118	belongs to the thioredoxin family
G3W91_RS06370	COG0492	ferredoxin-NADP+ reductase activity
G3W91_RS06375	COG0501	Belongs to the peptidase M48B family
G3W91_RS06380	COG4566	intracellular signal transduction
G3W91_RS06390	COG2823	Periplasmic or secreted lipoprotein
G3W91_RS06400	COG0071	Belongs to the small heat shock protein (HSP20) family
G3W91_RS06410	COG0542	response to heat
G3W91_RS06415	COG2205	protein histidine kinase activity
G3W91_RS06415	COG0745	RESPONSE REGULATOR receiver
G3W91_RS06415	COG4191	Histidine kinase
G3W91_RS06420	COG1802	Transcriptional regulator
G3W91_RS06435	COG2721	sulfolactate sulfo-lyase activity
G3W91_RS06440	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
G3W91_RS06445	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
G3W91_RS06455	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G3W91_RS06460	COG3181	Tripartite tricarboxylate transporter family receptor
G3W91_RS06475	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W91_RS06490	COG0583	DNA-binding transcription factor activity
G3W91_RS06505	COG2814	Major facilitator Superfamily
G3W91_RS06510	COG0583	DNA-binding transcription factor activity
G3W91_RS06545	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
G3W91_RS06585	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G3W91_RS06595	COG2130	NADP-dependent
G3W91_RS06605	COG2814	Major facilitator Superfamily
G3W91_RS06640	COG3278	Belongs to the heme-copper respiratory oxidase family
G3W91_RS06675	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G3W91_RS06680	COG0635	Involved in the biosynthesis of porphyrin-containing compound
G3W91_RS06695	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
G3W91_RS06700	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
G3W91_RS06705	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
G3W91_RS06710	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G3W91_RS06715	COG0784	Response regulator, receiver
G3W91_RS06715	COG4191	Histidine kinase
G3W91_RS06730	COG3108	Peptidase M15
G3W91_RS06745	COG1136	(ABC) transporter
G3W91_RS06765	COG1028	Short-chain dehydrogenase reductase Sdr
G3W91_RS06785	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
G3W91_RS06795	COG0589	response to stress
G3W91_RS06815	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
G3W91_RS06830	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W91_RS06835	COG0179	Fumarylacetoacetate (FAA) hydrolase
G3W91_RS06895	COG0583	DNA-binding transcription factor activity
G3W91_RS06905	COG0346	lactoylglutathione lyase activity
G3W91_RS06910	COG0655	NAD(P)H dehydrogenase (quinone) activity
G3W91_RS06930	COG0154	amidase activity
G3W91_RS06945	COG2376	Dihydroxyacetone kinase
G3W91_RS06950	COG3181	Tripartite tricarboxylate transporter family receptor
G3W91_RS06955	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G3W91_RS06965	COG2207	Transcriptional regulator
G3W91_RS06970	COG2197	response regulator
G3W91_RS06995	COG2208	phosphoserine phosphatase activity
G3W91_RS07050	COG3038	cytochrome b561
G3W91_RS07055	COG2814	Major facilitator Superfamily
G3W91_RS07060	COG0583	DNA-binding transcription factor activity
G3W91_RS07070	COG3468	outer membrane autotransporter barrel domain protein
G3W91_RS07075	COG1640	4-alpha-glucanotransferase
G3W91_RS07080	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
G3W91_RS07090	COG0668	transmembrane transport
G3W91_RS07095	COG0366	Alpha amylase catalytic
G3W91_RS07100	COG0366	Alpha amylase catalytic
G3W91_RS07105	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
G3W91_RS07145	COG0402	S-adenosylhomocysteine deaminase activity
G3W91_RS07165	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
G3W91_RS07165	COG0189	ligase activity
G3W91_RS07170	COG0189	ligase activity
G3W91_RS07170	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
G3W91_RS07175	COG1132	(ABC) transporter
G3W91_RS07185	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
G3W91_RS07190	COG4178	(ABC) transporter
G3W91_RS07260	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
G3W91_RS07265	COG1765	OsmC-like protein
G3W91_RS07270	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
G3W91_RS07280	COG0747	negative chemotaxis
G3W91_RS07290	COG1473	amidohydrolase
G3W91_RS07295	COG4166	transmembrane transport
G3W91_RS07300	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G3W91_RS07305	COG0444	Belongs to the ABC transporter superfamily
G3W91_RS07310	COG4608	Belongs to the ABC transporter superfamily
G3W91_RS07315	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
G3W91_RS07330	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
G3W91_RS07335	COG0166	Belongs to the GPI family
G3W91_RS07340	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G3W91_RS07355	COG0459	protein refolding
G3W91_RS07360	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
G3W91_RS07375	COG1012	belongs to the aldehyde dehydrogenase family
G3W91_RS07395	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
G3W91_RS07415	COG1028	Short-chain dehydrogenase reductase Sdr
G3W91_RS07415	COG3321	synthase
G3W91_RS07415	COG0604	alcohol dehydrogenase
G3W91_RS07465	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G3W91_RS07470	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G3W91_RS07515	COG4772	TonB-dependent receptor
G3W91_RS07525	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
G3W91_RS07535	COG1560	Kdo2-lipid A biosynthetic process
G3W91_RS07540	COG2267	carboxylic ester hydrolase activity
G3W91_RS07545	COG0218	Necessary for normal cell division and for the maintenance of normal septation
G3W91_RS07555	COG1333	cytochrome c biogenesis protein
G3W91_RS07560	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
G3W91_RS07565	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
G3W91_RS07570	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
G3W91_RS07580	COG1965	Belongs to the frataxin family
G3W91_RS07615	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
G3W91_RS07625	COG0232	Belongs to the dGTPase family. Type 2 subfamily
G3W91_RS07650	COG0070	glutamate synthase
G3W91_RS07650	COG0069	glutamate synthase activity
G3W91_RS07650	COG0067	glutamate synthase
G3W91_RS07660	COG1127	ABC transporter
G3W91_RS07665	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G3W91_RS07670	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G3W91_RS07675	COG2853	Lipoprotein
G3W91_RS07690	COG1131	(ABC) transporter
G3W91_RS07695	COG0842	Transport permease protein
G3W91_RS07700	COG5007	Belongs to the BolA IbaG family
G3W91_RS07705	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
G3W91_RS07710	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
G3W91_RS07725	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
G3W91_RS07730	COG0131	Imidazoleglycerol-phosphate dehydratase
G3W91_RS07740	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
G3W91_RS07745	COG3468	outer membrane autotransporter barrel domain protein
G3W91_RS07755	COG0107	imidazoleglycerol-phosphate synthase activity
G3W91_RS07760	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
G3W91_RS07765	COG0140	phosphoribosyl-ATP diphosphatase activity
G3W91_RS07775	COG0537	adenosine 5'-monophosphoramidase activity
G3W91_RS07780	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G3W91_RS07785	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G3W91_RS07790	COG0805	protein transport
G3W91_RS07795	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G3W91_RS07800	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
G3W91_RS07805	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
G3W91_RS07810	COG1970	mechanosensitive ion channel activity
G3W91_RS07815	COG0723	plastoquinol--plastocyanin reductase activity
G3W91_RS07820	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
G3W91_RS07825	COG2857	Cytochrome c1
G3W91_RS07830	COG0625	glutathione transferase activity
G3W91_RS07835	COG2969	positive regulation of protein catabolic process
G3W91_RS07845	COG1335	isochorismatase
G3W91_RS07850	COG2309	aminopeptidase activity
G3W91_RS07855	COG0596	Alpha beta hydrolase
G3W91_RS07860	COG3473	Maleate cis-trans isomerase
G3W91_RS07870	COG1741	Belongs to the pirin family
G3W91_RS07880	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
G3W91_RS07900	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
G3W91_RS07910	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
G3W91_RS07930	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G3W91_RS07940	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3W91_RS07980	COG0653	protein targeting
G3W91_RS07995	COG0494	nUDIX hydrolase
G3W91_RS08000	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
G3W91_RS08005	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
G3W91_RS08015	COG1696	Membrane protein involved in D-alanine export
G3W91_RS08025	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
G3W91_RS08045	COG0438	transferase activity, transferring glycosyl groups
G3W91_RS08065	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
G3W91_RS08095	COG0463	Glycosyl transferase, family 2
G3W91_RS08100	COG0165	Argininosuccinate lyase
G3W91_RS08105	COG3275	phosphorelay sensor kinase activity
G3W91_RS08130	COG0477	Major facilitator Superfamily
G3W91_RS08145	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
G3W91_RS08165	COG4948	Mandelate Racemase Muconate Lactonizing
G3W91_RS08195	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
G3W91_RS08210	COG1737	Transcriptional regulator
G3W91_RS08220	COG1012	belongs to the aldehyde dehydrogenase family
G3W91_RS08235	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
G3W91_RS08240	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
G3W91_RS08245	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G3W91_RS08255	COG2721	sulfolactate sulfo-lyase activity
G3W91_RS08260	COG4948	Mandelate Racemase Muconate Lactonizing
G3W91_RS08310	COG1737	Transcriptional regulator
G3W91_RS08315	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G3W91_RS08365	COG1196	nuclear chromosome segregation
G3W91_RS08370	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
G3W91_RS08380	COG0732	type I restriction modification DNA specificity domain
G3W91_RS08385	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
G3W91_RS08435	COG0142	geranyltranstransferase activity
G3W91_RS08440	COG0261	This protein binds to 23S rRNA in the presence of protein L20
G3W91_RS08445	COG0211	Belongs to the bacterial ribosomal protein bL27 family
G3W91_RS08450	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
G3W91_RS08455	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
G3W91_RS08465	COG0494	nUDIX hydrolase
G3W91_RS08470	COG0442	prolyl-tRNA aminoacylation
G3W91_RS08475	COG0741	lytic transglycosylase activity
G3W91_RS08480	COG1253	flavin adenine dinucleotide binding
G3W91_RS08485	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
G3W91_RS08495	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
G3W91_RS08500	COG2890	protein-(glutamine-N5) methyltransferase activity
G3W91_RS08505	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
G3W91_RS08510	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
G3W91_RS08520	COG3264	Mechanosensitive ion channel
G3W91_RS08520	COG1196	nuclear chromosome segregation
G3W91_RS08525	COG0584	glycerophosphoryl diester phosphodiesterase
G3W91_RS08530	COG3842	ATPase activity
G3W91_RS08535	COG0395	ABC-type sugar transport system, permease component
G3W91_RS08540	COG1175	transmembrane transport
G3W91_RS08550	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G3W91_RS08570	COG2226	methyltransferase
G3W91_RS08585	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
G3W91_RS08590	COG4145	pantothenate transmembrane transporter activity
G3W91_RS08605	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
G3W91_RS08615	COG3568	Endonuclease Exonuclease Phosphatase
G3W91_RS08620	COG0302	gtp cyclohydrolase
G3W91_RS08660	COG5487	UPF0391 membrane protein
G3W91_RS08665	COG4585	Histidine kinase
G3W91_RS08670	COG2197	response regulator
G3W91_RS08685	COG2982	Protein involved in outer membrane biogenesis
G3W91_RS08690	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
G3W91_RS08695	COG0793	Belongs to the peptidase S41A family
G3W91_RS08700	COG0588	phosphoglycerate mutase activity
G3W91_RS08705	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G3W91_RS08710	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
G3W91_RS08715	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
G3W91_RS08720	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
G3W91_RS08730	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
G3W91_RS08740	COG0720	synthase
G3W91_RS08745	COG0602	queuosine metabolic process
G3W91_RS08750	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
G3W91_RS08755	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
G3W91_RS08760	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
G3W91_RS08765	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
G3W91_RS08785	COG0659	secondary active sulfate transmembrane transporter activity
G3W91_RS08795	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G3W91_RS08795	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G3W91_RS08800	COG3132	Protein of unknown function, DUF480
G3W91_RS08805	COG0489	protein tyrosine kinase activity
G3W91_RS08810	COG0583	DNA-binding transcription factor activity
G3W91_RS08825	COG3383	formate dehydrogenase (NAD+) activity
G3W91_RS08855	COG0243	molybdopterin cofactor binding
G3W91_RS08855	COG3383	formate dehydrogenase (NAD+) activity
G3W91_RS08860	COG0437	4 iron, 4 sulfur cluster binding
G3W91_RS08885	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
G3W91_RS08895	COG0626	cystathionine gamma-synthase activity
G3W91_RS08905	COG0247	lactate metabolic process
G3W91_RS08910	COG1592	Rubrerythrin
G3W91_RS08915	COG3491	Belongs to the iron ascorbate-dependent oxidoreductase family
G3W91_RS08945	COG2003	Belongs to the UPF0758 family
G3W91_RS08950	COG1047	Peptidyl-prolyl cis-trans
G3W91_RS08955	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
G3W91_RS08960	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
G3W91_RS08970	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
G3W91_RS09015	COG2072	flavoprotein involved in K transport
G3W91_RS09025	COG0438	transferase activity, transferring glycosyl groups
G3W91_RS09030	COG2144	transferase activity, transferring acyl groups
G3W91_RS09055	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G3W91_RS09060	COG1028	Short-chain dehydrogenase reductase Sdr
G3W91_RS09065	COG2239	Acts as a magnesium transporter
G3W91_RS09075	COG2902	Dehydrogenase
G3W91_RS09085	COG5002	protein histidine kinase activity
G3W91_RS09095	COG0180	Tryptophanyl-tRNA synthetase
G3W91_RS09100	COG1994	Peptidase M50
G3W91_RS09105	COG0009	L-threonylcarbamoyladenylate synthase
G3W91_RS09115	COG0613	PHP domain protein
G3W91_RS09195	COG1126	abc transporter atp-binding protein
G3W91_RS09210	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G3W91_RS09235	COG0477	Major facilitator Superfamily
G3W91_RS09240	COG0829	nickel cation binding
G3W91_RS09260	COG1960	acyl-CoA dehydrogenase activity
G3W91_RS09270	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W91_RS09275	COG1024	Enoyl-CoA hydratase
G3W91_RS09285	COG1024	Enoyl-CoA hydratase
G3W91_RS09290	COG1802	Transcriptional regulator
G3W91_RS09295	COG0318	PFAM AMP-dependent synthetase and ligase
G3W91_RS09300	COG1960	acyl-CoA dehydrogenase activity
G3W91_RS09305	COG1250	3-hydroxyacyl-CoA dehydrogenase
G3W91_RS09305	COG1024	Enoyl-CoA hydratase
G3W91_RS09310	COG0183	Belongs to the thiolase family
G3W91_RS09360	COG1960	acyl-CoA dehydrogenase activity
G3W91_RS09365	COG1960	acyl-CoA dehydrogenase activity
G3W91_RS09380	COG3181	Tripartite tricarboxylate transporter family receptor
G3W91_RS09415	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G3W91_RS09425	COG0655	NAD(P)H dehydrogenase (quinone) activity
G3W91_RS09430	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
G3W91_RS09485	COG3181	Tripartite tricarboxylate transporter family receptor
G3W91_RS09490	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
G3W91_RS09495	COG0583	DNA-binding transcription factor activity
G3W91_RS09525	COG0515	serine threonine protein kinase
G3W91_RS09525	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G3W91_RS09540	COG3181	Tripartite tricarboxylate transporter family receptor
G3W91_RS09545	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W91_RS09550	COG1283	sodium-dependent phosphate transmembrane transporter activity
G3W91_RS09565	COG0583	DNA-binding transcription factor activity
G3W91_RS09585	COG0392	lysyltransferase activity
G3W91_RS09605	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3W91_RS09610	COG1116	anion transmembrane transporter activity
G3W91_RS09635	COG0280	phosphate acetyltransferase
G3W91_RS09635	COG0281	malic enzyme
G3W91_RS09665	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
G3W91_RS09675	COG3128	pkhd-type hydroxylase
G3W91_RS09690	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
G3W91_RS09715	COG4948	Mandelate Racemase Muconate Lactonizing
G3W91_RS09720	COG0583	DNA-binding transcription factor activity
G3W91_RS09725	COG2205	protein histidine kinase activity
G3W91_RS09745	COG3665	Urea carboxylase-associated protein
G3W91_RS09770	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G3W91_RS09780	COG1609	Transcriptional regulator
G3W91_RS09790	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
G3W91_RS09795	COG0066	3-isopropylmalate dehydratase activity
G3W91_RS09825	COG0318	PFAM AMP-dependent synthetase and ligase
G3W91_RS09830	COG0318	PFAM AMP-dependent synthetase and ligase
G3W91_RS09880	COG0583	DNA-binding transcription factor activity
G3W91_RS09890	COG0402	S-adenosylhomocysteine deaminase activity
G3W91_RS09895	COG4608	Belongs to the ABC transporter superfamily
G3W91_RS09900	COG0444	Belongs to the ABC transporter superfamily
G3W91_RS09905	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G3W91_RS09950	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G3W91_RS09960	COG4521	taurine ABC transporter
G3W91_RS09965	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
G3W91_RS09970	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3W91_RS09975	COG0625	glutathione transferase activity
G3W91_RS09980	COG0477	Major facilitator Superfamily
G3W91_RS09990	COG1414	Transcriptional regulator
G3W91_RS10015	COG1960	acyl-CoA dehydrogenase activity
G3W91_RS10060	COG0583	DNA-binding transcription factor activity
G3W91_RS10070	COG0318	PFAM AMP-dependent synthetase and ligase
G3W91_RS10075	COG1012	belongs to the aldehyde dehydrogenase family
G3W91_RS10105	COG4964	Belongs to the GSP D family
G3W91_RS10160	COG2197	response regulator
G3W91_RS10165	COG4585	Histidine kinase
G3W91_RS10180	COG1414	Transcriptional regulator
G3W91_RS10195	COG0583	DNA-binding transcription factor activity
G3W91_RS10200	COG0243	molybdopterin cofactor binding
G3W91_RS10205	COG0437	4 iron, 4 sulfur cluster binding
G3W91_RS10210	COG3302	dmso reductase anchor subunit
G3W91_RS10230	COG2226	methyltransferase
G3W91_RS10250	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G3W91_RS10280	COG0640	Transcriptional regulator
G3W91_RS10300	COG2304	oxidoreductase activity
G3W91_RS10320	COG0583	DNA-binding transcription factor activity
G3W91_RS10330	COG0154	amidase activity
G3W91_RS10350	COG1815	bacterial-type flagellum-dependent cell motility
G3W91_RS10355	COG1558	bacterial-type flagellum-dependent cell motility
G3W91_RS10365	COG1749	Flagellar hook protein flgE
G3W91_RS10380	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
G3W91_RS10385	COG1706	bacterial-type flagellum-dependent cell motility
G3W91_RS10390	COG3951	Flagellar rod assembly protein muramidase FlgJ
G3W91_RS10390	COG1705	Flagellar rod assembly protein muramidase FlgJ
G3W91_RS10395	COG0835	chemotaxis
G3W91_RS10400	COG0840	transmembrane signaling receptor activity
G3W91_RS10405	COG0835	chemotaxis
G3W91_RS10420	COG0840	transmembrane signaling receptor activity
G3W91_RS10425	COG1256	bacterial-type flagellum assembly
G3W91_RS10440	COG2020	methyltransferase activity
G3W91_RS10445	COG2267	carboxylic ester hydrolase activity
G3W91_RS10455	COG0432	Pfam Uncharacterised protein family UPF0047
G3W91_RS10505	COG0745	RESPONSE REGULATOR receiver
G3W91_RS10510	COG1764	response to oxidative stress
G3W91_RS10520	COG0583	DNA-binding transcription factor activity
G3W91_RS10525	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W91_RS10540	COG1024	Enoyl-CoA hydratase
G3W91_RS10550	COG0183	Belongs to the thiolase family
G3W91_RS10565	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
G3W91_RS10570	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
G3W91_RS10580	COG1845	cytochrome c oxidase, subunit III
G3W91_RS10615	COG1338	Plays a role in the flagellum-specific transport system
G3W91_RS10625	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
G3W91_RS10630	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
G3W91_RS10635	COG1580	Controls the rotational direction of flagella during chemotaxis
G3W91_RS10640	COG3144	bacterial-type flagellum assembly
G3W91_RS10650	COG1157	protein secretion by the type III secretion system
G3W91_RS10655	COG1317	bacterial-type flagellum organization
G3W91_RS10660	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
G3W91_RS10665	COG1766	The M ring may be actively involved in energy transduction
G3W91_RS10670	COG1677	Flagellar hook-basal body complex protein FliE
G3W91_RS10680	COG1334	flagellar protein FlaG
G3W91_RS10685	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
G3W91_RS10705	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
G3W91_RS10730	COG0643	Histidine kinase
G3W91_RS10730	COG2198	Histidine kinase
G3W91_RS10735	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
G3W91_RS10740	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
G3W91_RS10745	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
G3W91_RS10760	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
G3W91_RS10805	COG1191	sigma factor activity
G3W91_RS10820	COG1716	ATPase activity
G3W91_RS10850	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
G3W91_RS10855	COG0308	aminopeptidase N
G3W91_RS10865	COG2267	carboxylic ester hydrolase activity
G3W91_RS10870	COG0667	Aldo Keto reductase
G3W91_RS10875	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
G3W91_RS10880	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
G3W91_RS10885	COG0251	oxidation-reduction process
G3W91_RS10895	COG1666	GTP binding
G3W91_RS10900	COG0812	UDP-N-acetylmuramate dehydrogenase activity
G3W91_RS10905	COG0137	argininosuccinate synthase activity
G3W91_RS10910	COG3123	guanosine phosphorylase activity
G3W91_RS10920	COG1393	Belongs to the ArsC family
G3W91_RS10925	COG0285	dihydrofolate synthase activity
G3W91_RS10950	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G3W91_RS10975	COG0318	PFAM AMP-dependent synthetase and ligase
G3W91_RS10980	COG0183	Belongs to the thiolase family
G3W91_RS10990	COG0583	DNA-binding transcription factor activity
G3W91_RS10995	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
G3W91_RS11015	COG1529	Aldehyde oxidase and xanthine dehydrogenase
G3W91_RS11025	COG2252	PERMEase
G3W91_RS11055	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
G3W91_RS11075	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
G3W91_RS11080	COG2199	diguanylate cyclase activity
G3W91_RS11080	COG2200	EAL domain
G3W91_RS11080	COG3287	FIST C domain
G3W91_RS11105	COG0402	S-adenosylhomocysteine deaminase activity
G3W91_RS11110	COG0717	Belongs to the dCTP deaminase family
G3W91_RS11115	COG2321	neutral zinc metallopeptidase
G3W91_RS11120	COG0513	Belongs to the DEAD box helicase family
G3W91_RS11125	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
G3W91_RS11130	COG1253	flavin adenine dinucleotide binding
G3W91_RS11170	COG2084	Dehydrogenase
G3W91_RS11175	COG3622	Belongs to the hyi family
G3W91_RS11180	COG3960	tartronate-semialdehyde synthase activity
G3W91_RS11185	COG0583	DNA-binding transcription factor activity
G3W91_RS11190	COG0840	transmembrane signaling receptor activity
G3W91_RS11240	COG2186	Transcriptional regulator
G3W91_RS11245	COG1301	dicarboxylic acid transport
G3W91_RS11305	COG3246	L-lysine catabolic process to acetate
G3W91_RS11310	COG1028	Short-chain dehydrogenase reductase Sdr
G3W91_RS11335	COG0318	PFAM AMP-dependent synthetase and ligase
G3W91_RS11345	COG0625	glutathione transferase activity
G3W91_RS11355	COG1902	pentaerythritol trinitrate reductase activity
G3W91_RS11365	COG0583	DNA-binding transcription factor activity
G3W91_RS11370	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G3W91_RS11380	COG1538	Outer membrane efflux protein
G3W91_RS11420	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
G3W91_RS11450	COG1028	Short-chain dehydrogenase reductase Sdr
G3W91_RS11480	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G3W91_RS11485	COG4948	Mandelate Racemase Muconate Lactonizing
G3W91_RS11490	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G3W91_RS11495	COG4948	Mandelate Racemase Muconate Lactonizing
G3W91_RS11520	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G3W91_RS11530	COG1473	amidohydrolase
G3W91_RS11535	COG1522	sequence-specific DNA binding
G3W91_RS11540	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
G3W91_RS11565	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G3W91_RS11570	COG4166	transmembrane transport
G3W91_RS11575	COG0601	transmembrane transport
G3W91_RS11580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G3W91_RS11590	COG0473	3-isopropylmalate dehydrogenase activity
G3W91_RS11595	COG1012	belongs to the aldehyde dehydrogenase family
G3W91_RS11600	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G3W91_RS11615	COG3119	arylsulfatase activity
G3W91_RS11620	COG0583	DNA-binding transcription factor activity
G3W91_RS11625	COG0277	FAD linked oxidase domain protein
G3W91_RS11645	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
G3W91_RS11650	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W91_RS11655	COG2301	Belongs to the HpcH HpaI aldolase family
G3W91_RS11665	COG0583	DNA-binding transcription factor activity
G3W91_RS11675	COG2828	Protein conserved in bacteria
G3W91_RS11685	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G3W91_RS11690	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
G3W91_RS11695	COG1609	Transcriptional regulator
G3W91_RS11700	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G3W91_RS11710	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G3W91_RS11715	COG0589	response to stress
G3W91_RS11750	COG0071	Belongs to the small heat shock protein (HSP20) family
G3W91_RS11760	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G3W91_RS11765	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G3W91_RS11775	COG0574	Belongs to the PEP-utilizing enzyme family
G3W91_RS11775	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
G3W91_RS11780	COG0589	response to stress
G3W91_RS11795	COG1136	(ABC) transporter
G3W91_RS11810	COG0392	lysyltransferase activity
G3W91_RS11835	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G3W91_RS11840	COG0318	PFAM AMP-dependent synthetase and ligase
G3W91_RS11855	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G3W91_RS11860	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
G3W91_RS11865	COG0022	dehydrogenase e1 component
G3W91_RS11865	COG0508	dehydrogenase complex catalyzes the overall conversion of
G3W91_RS11875	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G3W91_RS11880	COG2116	formate transmembrane transporter activity
G3W91_RS11890	COG0183	Belongs to the thiolase family
G3W91_RS11895	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
G3W91_RS11905	COG4876	unkown
G3W91_RS11915	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
G3W91_RS11920	COG0459	protein refolding
G3W91_RS11960	COG0542	response to heat
G3W91_RS11965	COG0058	SHG alpha-glucan phosphorylase activity
G3W91_RS11980	COG0642	Histidine kinase
G3W91_RS12000	COG1022	Amp-dependent synthetase and ligase
G3W91_RS12015	COG1136	(ABC) transporter
G3W91_RS12020	COG4591	ABC-type transport system involved in lipoprotein release permease component
G3W91_RS12030	COG5002	protein histidine kinase activity
G3W91_RS12030	COG2176	DNA-directed DNA polymerase activity
G3W91_RS12035	COG0745	RESPONSE REGULATOR receiver
G3W91_RS12055	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G3W91_RS12060	COG3162	membrane
G3W91_RS12090	COG3850	Histidine kinase
G3W91_RS12095	COG2197	response regulator
G3W91_RS12110	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
G3W91_RS12115	COG1140	nitrate reductase beta subunit
G3W91_RS12120	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
G3W91_RS12125	COG2181	nitrate reductase activity
G3W91_RS12130	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G3W91_RS12160	COG0589	response to stress
G3W91_RS12225	COG0745	RESPONSE REGULATOR receiver
G3W91_RS12235	COG2205	protein histidine kinase activity
G3W91_RS12265	COG0820	rRNA (adenine-C2-)-methyltransferase activity
G3W91_RS12270	COG1529	Aldehyde oxidase and xanthine dehydrogenase
G3W91_RS12275	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
G3W91_RS12280	COG2080	2 iron, 2 sulfur cluster binding
G3W91_RS12290	COG2814	Major facilitator Superfamily
G3W91_RS12300	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G3W91_RS12305	COG3181	Tripartite tricarboxylate transporter family receptor
G3W91_RS12315	COG0583	DNA-binding transcription factor activity
G3W91_RS12340	COG3181	Tripartite tricarboxylate transporter family receptor
G3W91_RS12360	COG3181	Tripartite tricarboxylate transporter family receptor
G3W91_RS12370	COG3181	Tripartite tricarboxylate transporter family receptor
G3W91_RS12380	COG0656	L-ascorbic acid biosynthetic process
G3W91_RS12385	COG2233	PERMEase
G3W91_RS12405	COG3181	Tripartite tricarboxylate transporter family receptor
G3W91_RS12410	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G3W91_RS12420	COG3754	Rhamnan synthesis protein F
G3W91_RS12425	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G3W91_RS12440	COG2186	Transcriptional regulator
G3W91_RS12445	COG2351	hydroxyisourate hydrolase activity
G3W91_RS12480	COG1131	(ABC) transporter
G3W91_RS12485	COG0842	Transport permease protein
G3W91_RS12490	COG0842	Transport permease protein
G3W91_RS12525	COG0674	pyruvate-flavodoxin oxidoreductase activity
G3W91_RS12525	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
G3W91_RS12535	COG1733	regulation of RNA biosynthetic process
G3W91_RS12560	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W91_RS12565	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G3W91_RS12575	COG3181	Tripartite tricarboxylate transporter family receptor
G3W91_RS12605	COG3181	Tripartite tricarboxylate transporter family receptor
G3W91_RS12645	COG2815	serine threonine protein kinase
G3W91_RS12645	COG0515	serine threonine protein kinase
G3W91_RS12760	COG2217	Heavy metal translocating P-type atpase
G3W91_RS12765	COG0789	Transcriptional regulator
G3W91_RS12770	COG2010	Cytochrome c
G3W91_RS12770	COG1529	Aldehyde oxidase and xanthine dehydrogenase
G3W91_RS12785	COG0697	spore germination
G3W91_RS12795	COG2169	Transcriptional regulator
G3W91_RS12810	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
G3W91_RS12835	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
G3W91_RS12850	COG1309	transcriptional regulator
G3W91_RS12855	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G3W91_RS12870	COG1181	Belongs to the D-alanine--D-alanine ligase family
G3W91_RS12875	COG0527	aspartate kinase activity
G3W91_RS12880	COG0667	Aldo Keto reductase
G3W91_RS12890	COG0259	pyridoxamine-phosphate oxidase activity
G3W91_RS12895	COG0583	DNA-binding transcription factor activity
G3W91_RS12920	COG0800	Aldolase
G3W91_RS12930	COG0346	lactoylglutathione lyase activity
G3W91_RS12935	COG3842	ATPase activity
G3W91_RS12945	COG1840	ABC-type Fe3 transport system, periplasmic component
G3W91_RS12950	COG0318	PFAM AMP-dependent synthetase and ligase
G3W91_RS12955	COG2070	2-Nitropropane dioxygenase
G3W91_RS12960	COG4221	oxidoreductase activity
G3W91_RS12985	COG1028	Short-chain dehydrogenase reductase Sdr
G3W91_RS13000	COG1609	Transcriptional regulator
G3W91_RS13020	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3W91_RS13025	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3W91_RS13030	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G3W91_RS13080	COG0800	Aldolase
G3W91_RS13090	COG0129	dihydroxy-acid dehydratase activity
G3W91_RS13095	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G3W91_RS13100	COG2186	Transcriptional regulator
G3W91_RS13110	COG1175	transmembrane transport
G3W91_RS13120	COG3842	ATPase activity
G3W91_RS13125	COG0513	Belongs to the DEAD box helicase family
G3W91_RS13135	COG0488	(ABC) transporter
G3W91_RS13140	COG2133	pyrroloquinoline quinone binding
G3W91_RS13165	COG3191	aminopeptidase activity
G3W91_RS13175	COG0789	Transcriptional regulator
G3W91_RS13180	COG0584	glycerophosphoryl diester phosphodiesterase
G3W91_RS13195	COG0765	amino acid transport
G3W91_RS13200	COG0765	amino acid transport
G3W91_RS13215	COG1764	response to oxidative stress
G3W91_RS13220	COG0318	PFAM AMP-dependent synthetase and ligase
G3W91_RS13255	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G3W91_RS13260	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
G3W91_RS13275	COG0589	response to stress
G3W91_RS13280	COG0564	pseudouridine synthase activity
G3W91_RS13300	COG2354	Protein conserved in bacteria
G3W91_RS13305	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
G3W91_RS13315	COG3468	outer membrane autotransporter barrel domain protein
G3W91_RS13330	COG0400	carboxylic ester hydrolase activity
G3W91_RS13335	COG2918	glutathione biosynthetic process
G3W91_RS13340	COG2423	ornithine cyclodeaminase activity
G3W91_RS13355	COG0789	Transcriptional regulator
G3W91_RS13360	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
G3W91_RS13370	COG3279	Response regulator of the LytR AlgR family
G3W91_RS13375	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
G3W91_RS13420	COG2175	clavaminate synthase activity
G3W91_RS13455	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G3W91_RS13465	COG3279	Response regulator of the LytR AlgR family
G3W91_RS13470	COG3275	phosphorelay sensor kinase activity
G3W91_RS13515	COG1968	undecaprenyl-diphosphatase activity
G3W91_RS13540	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
G3W91_RS13550	COG3119	arylsulfatase activity
G3W91_RS13565	COG1846	Transcriptional regulator
G3W91_RS13570	COG3181	Tripartite tricarboxylate transporter family receptor
G3W91_RS13575	COG0583	DNA-binding transcription factor activity
G3W91_RS13585	COG1289	transmembrane transporter activity
G3W91_RS13600	COG1045	serine acetyltransferase
G3W91_RS13605	COG0521	Mo-molybdopterin cofactor biosynthetic process
G3W91_RS13615	COG0312	modulator of DNA gyrase
G3W91_RS13625	COG0828	Belongs to the bacterial ribosomal protein bS21 family
G3W91_RS13630	COG2081	HI0933 family
G3W91_RS13645	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
G3W91_RS13650	COG0243	molybdopterin cofactor binding
G3W91_RS13660	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G3W91_RS13670	COG2223	nitrite transmembrane transporter activity
G3W91_RS13680	COG1116	anion transmembrane transporter activity
G3W91_RS13685	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3W91_RS13690	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G3W91_RS13695	COG3707	response regulator
G3W91_RS13700	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
G3W91_RS13710	COG0071	Belongs to the small heat shock protein (HSP20) family
G3W91_RS13715	COG0683	leucine binding
G3W91_RS13720	COG0436	Aminotransferase
G3W91_RS13725	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
G3W91_RS13730	COG1185	polyribonucleotide nucleotidyltransferase activity
G3W91_RS13740	COG0149	triose-phosphate isomerase activity
G3W91_RS13755	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G3W91_RS13760	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G3W91_RS13765	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G3W91_RS13770	COG0649	NAD binding
G3W91_RS13775	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
G3W91_RS13790	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
G3W91_RS13795	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G3W91_RS13805	COG0713	ATP synthesis coupled electron transport
G3W91_RS13820	COG1007	ATP synthesis coupled electron transport
G3W91_RS13830	COG0494	nUDIX hydrolase
G3W91_RS13840	COG1132	(ABC) transporter
G3W91_RS13845	COG1846	Transcriptional regulator
G3W91_RS13855	COG1566	PFAM secretion protein HlyD family protein
G3W91_RS13860	COG2814	Major facilitator Superfamily
G3W91_RS13915	COG0154	amidase activity
G3W91_RS13925	COG0477	Major facilitator Superfamily
G3W91_RS13935	COG1215	transferase activity, transferring glycosyl groups
G3W91_RS13965	COG2194	sulfuric ester hydrolase activity
G3W91_RS13975	COG0154	amidase activity
G3W91_RS13980	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W91_RS13985	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
G3W91_RS13990	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G3W91_RS13990	COG3321	synthase
G3W91_RS13990	COG0604	alcohol dehydrogenase
G3W91_RS13990	COG4221	oxidoreductase activity
G3W91_RS14000	COG0583	DNA-binding transcription factor activity
G3W91_RS14010	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
G3W91_RS14050	COG2186	Transcriptional regulator
G3W91_RS14065	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W91_RS14075	COG1136	(ABC) transporter
G3W91_RS14080	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
G3W91_RS14085	COG2814	Major facilitator Superfamily
G3W91_RS14095	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
G3W91_RS14100	COG0586	Pfam SNARE associated Golgi protein
G3W91_RS14115	COG0860	N-Acetylmuramoyl-L-alanine amidase
G3W91_RS14120	COG0802	atpase or kinase
G3W91_RS14125	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
G3W91_RS14140	COG3181	Tripartite tricarboxylate transporter family receptor
G3W91_RS14145	COG4974	Belongs to the 'phage' integrase family
G3W91_RS14180	COG2833	Protein of unknown function (DUF455)
G3W91_RS14190	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
G3W91_RS14205	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
G3W91_RS14210	COG0148	phosphopyruvate hydratase activity
G3W91_RS14220	COG2877	3-deoxy-8-phosphooctulonate synthase activity
G3W91_RS14225	COG0504	CTP synthase activity
G3W91_RS14230	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
G3W91_RS14240	COG0756	dUTP diphosphatase activity
G3W91_RS14255	COG1047	Peptidyl-prolyl cis-trans
G3W91_RS14260	COG2850	peptidyl-arginine hydroxylation
G3W91_RS14275	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
G3W91_RS14280	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
G3W91_RS14285	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G3W91_RS14315	COG0741	lytic transglycosylase activity
G3W91_RS14355	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
G3W91_RS14365	COG0765	amino acid transport
G3W91_RS14370	COG0765	amino acid transport
G3W91_RS14380	COG1126	abc transporter atp-binding protein
G3W91_RS14390	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G3W91_RS14400	COG1609	Transcriptional regulator
G3W91_RS14410	COG1487	ribonuclease activity
G3W91_RS14420	COG1012	belongs to the aldehyde dehydrogenase family
G3W91_RS14425	COG1522	sequence-specific DNA binding
G3W91_RS14455	COG2308	Evidence 4 Homologs of previously reported genes of
G3W91_RS14465	COG2274	protein secretion by the type I secretion system
G3W91_RS14485	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
G3W91_RS14505	COG3842	ATPase activity
G3W91_RS14515	COG0395	ABC-type sugar transport system, permease component
G3W91_RS14540	COG2951	lytic endotransglycosylase activity
G3W91_RS14555	COG0714	Associated with various cellular activities
G3W91_RS14565	COG3264	Mechanosensitive ion channel
G3W91_RS14565	COG1511	domain protein
G3W91_RS14580	COG1960	acyl-CoA dehydrogenase activity
G3W91_RS14600	COG4988	ABC transporter
G3W91_RS14605	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
G3W91_RS14610	COG1271	oxidase subunit
G3W91_RS14615	COG1294	oxidase, subunit
G3W91_RS14625	COG4251	negative regulation of phosphorylation
G3W91_RS14630	COG0784	Response regulator, receiver
G3W91_RS14635	COG0784	Response regulator, receiver
G3W91_RS14635	COG4191	Histidine kinase
G3W91_RS14655	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
G3W91_RS14665	COG0477	Major facilitator Superfamily
G3W91_RS14680	COG1414	Transcriptional regulator
G3W91_RS14685	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
G3W91_RS14695	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
G3W91_RS14735	COG0583	DNA-binding transcription factor activity
G3W91_RS14740	COG0477	Major facilitator Superfamily
G3W91_RS14755	COG4941	Belongs to the sigma-70 factor family
G3W91_RS14760	COG3795	YCII-related domain
G3W91_RS14775	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
G3W91_RS14785	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
G3W91_RS14785	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
G3W91_RS14790	COG0509	glycine decarboxylation via glycine cleavage system
G3W91_RS14795	COG0404	The glycine cleavage system catalyzes the degradation of glycine
G3W91_RS14815	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G3W91_RS14820	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G3W91_RS14825	COG2205	protein histidine kinase activity
G3W91_RS14825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G3W91_RS14835	COG1028	Short-chain dehydrogenase reductase Sdr
G3W91_RS14855	COG0642	Histidine kinase
G3W91_RS14860	COG0745	RESPONSE REGULATOR receiver
G3W91_RS14870	COG2194	sulfuric ester hydrolase activity
G3W91_RS14880	COG4302	ethanolamine ammonia-lyase activity
G3W91_RS14885	COG4303	Ethanolamine ammonia lyase large subunit
G3W91_RS14890	COG0545	Peptidyl-prolyl cis-trans isomerase
G3W91_RS14900	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
G3W91_RS14905	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
G3W91_RS14905	COG2169	Transcriptional regulator
G3W91_RS14915	COG3145	DNA-N1-methyladenine dioxygenase activity
G3W91_RS14925	COG2197	response regulator
G3W91_RS14940	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W91_RS14970	COG1024	Enoyl-CoA hydratase
G3W91_RS14980	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G3W91_RS15005	COG0406	alpha-ribazole phosphatase activity
G3W91_RS15010	COG2909	trisaccharide binding
G3W91_RS15015	COG2197	response regulator
G3W91_RS15020	COG2909	trisaccharide binding
G3W91_RS15020	COG2909	trisaccharide binding
G3W91_RS15025	COG2909	trisaccharide binding
G3W91_RS15025	COG2909	trisaccharide binding
G3W91_RS15030	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G3W91_RS15035	COG1183	phosphatidylcholine synthase activity
G3W91_RS15040	COG1160	GTP binding
G3W91_RS15055	COG1132	(ABC) transporter
G3W91_RS15060	COG3384	dioxygenase
G3W91_RS15225	COG0587	DNA-directed DNA polymerase activity
G3W91_RS15245	COG1309	transcriptional regulator
G3W91_RS15290	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G3W91_RS15295	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G3W91_RS15305	COG2116	formate transmembrane transporter activity
G3W91_RS15320	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
G3W91_RS15345	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
G3W91_RS15355	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G3W91_RS15360	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
G3W91_RS15380	COG1028	Short-chain dehydrogenase reductase Sdr
G3W91_RS15390	COG2267	carboxylic ester hydrolase activity
G3W91_RS15395	COG1414	Transcriptional regulator
G3W91_RS15405	COG0028	Belongs to the TPP enzyme family
G3W91_RS15410	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
G3W91_RS15415	COG1012	belongs to the aldehyde dehydrogenase family
G3W91_RS15430	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G3W91_RS15490	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
G3W91_RS15505	COG0084	hydrolase, TatD family'
G3W91_RS15520	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
G3W91_RS15525	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
G3W91_RS15535	COG2879	small protein
G3W91_RS15540	COG1966	Carbon starvation protein
G3W91_RS15585	COG3181	Tripartite tricarboxylate transporter family receptor
G3W91_RS15590	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G3W91_RS15640	COG2183	response to ionizing radiation
G3W91_RS15665	COG0583	DNA-binding transcription factor activity
G3W91_RS15670	COG0583	DNA-binding transcription factor activity
G3W91_RS15695	COG0534	Mate efflux family protein
G3W91_RS15720	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
G3W91_RS15735	COG0477	Major facilitator Superfamily
G3W91_RS15740	COG2814	Major facilitator Superfamily
G3W91_RS15745	COG2814	Major facilitator Superfamily
G3W91_RS15785	COG3008	intermembrane lipid transfer
G3W91_RS15785	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G3W91_RS15790	COG2995	paraquat-inducible protein a
G3W91_RS15795	COG2995	paraquat-inducible protein a
G3W91_RS15800	COG0583	DNA-binding transcription factor activity
G3W91_RS15805	COG2814	Major facilitator Superfamily
G3W91_RS15810	COG0667	Aldo Keto reductase
G3W91_RS15815	COG0745	RESPONSE REGULATOR receiver
G3W91_RS15830	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
G3W91_RS15840	COG5507	3-demethylubiquinone-9 3-methyltransferase
G3W91_RS15860	COG1960	acyl-CoA dehydrogenase activity
G3W91_RS15865	COG2130	NADP-dependent
G3W91_RS15885	COG1960	acyl-CoA dehydrogenase activity
G3W91_RS15890	COG0183	Belongs to the thiolase family
G3W91_RS15895	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G3W91_RS15900	COG1250	3-hydroxyacyl-CoA dehydrogenase
G3W91_RS15900	COG1024	Enoyl-CoA hydratase
G3W91_RS15910	COG0411	ABC transporter
G3W91_RS15920	COG0559	Belongs to the binding-protein-dependent transport system permease family
G3W91_RS15930	COG0318	PFAM AMP-dependent synthetase and ligase
G3W91_RS15935	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
G3W91_RS15940	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
G3W91_RS15945	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G3W91_RS15950	COG2917	probably involved in intracellular septation
G3W91_RS15960	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G3W91_RS15980	COG0047	phosphoribosylformylglycinamidine synthase activity
G3W91_RS15980	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
G3W91_RS15985	COG0024	Methionine aminopeptidase
G3W91_RS15990	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
G3W91_RS15995	COG2259	Doxx family
G3W91_RS16000	COG0242	peptide deformylase activity
G3W91_RS16010	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
G3W91_RS16020	COG1196	nuclear chromosome segregation
G3W91_RS16065	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
G3W91_RS16070	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
G3W91_RS16075	COG4208	sulfate ABC transporter
G3W91_RS16085	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
G3W91_RS16100	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
G3W91_RS16105	COG3550	peptidyl-serine autophosphorylation
G3W91_RS16120	COG1045	serine acetyltransferase
G3W91_RS16125	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
G3W91_RS16130	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
G3W91_RS16135	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G3W91_RS16135	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
G3W91_RS16150	COG0583	DNA-binding transcription factor activity
G3W91_RS16160	COG1272	protein, Hemolysin III
G3W91_RS16195	COG0175	sulfate reduction
G3W91_RS16200	COG2895	sulfate adenylyltransferase (ATP) activity
G3W91_RS16205	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
G3W91_RS16210	COG0492	ferredoxin-NADP+ reductase activity
G3W91_RS16215	COG0671	phosphoesterase, PA-phosphatase related
G3W91_RS16225	COG4654	Cytochrome c, class I
G3W91_RS16235	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G3W91_RS16250	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
G3W91_RS16255	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G3W91_RS16265	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
G3W91_RS16270	COG0114	fumarate hydratase activity
G3W91_RS16315	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
G3W91_RS16320	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
G3W91_RS16325	COG0740	serine-type endopeptidase activity
G3W91_RS16330	COG0544	peptidyl-prolyl cis-trans isomerase activity
G3W91_RS16345	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G3W91_RS16400	COG1011	Hydrolase
G3W91_RS16405	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
G3W91_RS16435	COG0411	ABC transporter
G3W91_RS16460	COG2197	response regulator
G3W91_RS16525	COG1028	Short-chain dehydrogenase reductase Sdr
G3W91_RS16530	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G3W91_RS16535	COG3181	Tripartite tricarboxylate transporter family receptor
G3W91_RS16540	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G3W91_RS16545	COG0583	DNA-binding transcription factor activity
G3W91_RS16555	COG1024	Enoyl-CoA hydratase
G3W91_RS16565	COG1960	acyl-CoA dehydrogenase activity
G3W91_RS16580	COG1028	Short-chain dehydrogenase reductase Sdr
G3W91_RS16595	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G3W91_RS16615	COG3181	Tripartite tricarboxylate transporter family receptor
G3W91_RS16625	COG0642	Histidine kinase
G3W91_RS16635	COG2326	polyphosphate kinase activity
G3W91_RS16645	COG1414	Transcriptional regulator
G3W91_RS16690	COG0037	tRNA processing
G3W91_RS16695	COG0825	malonyl-CoA metabolic process
G3W91_RS16705	COG0215	cysteine-tRNA ligase activity
G3W91_RS16725	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G3W91_RS16730	COG3228	Belongs to the MtfA family
G3W91_RS16745	COG0741	lytic transglycosylase activity
G3W91_RS16750	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
G3W91_RS16755	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
G3W91_RS16780	COG4968	Prepilin-type N-terminal cleavage methylation domain
G3W91_RS16785	COG4968	Prepilin-type N-terminal cleavage methylation domain
G3W91_RS16790	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G3W91_RS16790	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G3W91_RS16805	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
G3W91_RS16810	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
G3W91_RS16815	COG0436	Aminotransferase
G3W91_RS16820	COG0824	Thioesterase
G3W91_RS16825	COG0811	peptide transport
G3W91_RS16830	COG0848	biopolymer transport protein
G3W91_RS16850	COG1741	Belongs to the pirin family
G3W91_RS16860	COG2259	Doxx family
G3W91_RS16865	COG1741	Belongs to the pirin family
G3W91_RS16880	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G3W91_RS16885	COG0220	tRNA (guanine-N7-)-methyltransferase activity
G3W91_RS16900	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
G3W91_RS16930	COG0235	Class ii aldolase
G3W91_RS16945	COG3181	Tripartite tricarboxylate transporter family receptor
G3W91_RS16960	COG3119	arylsulfatase activity
G3W91_RS16965	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W91_RS16970	COG1024	Enoyl-CoA hydratase
G3W91_RS16975	COG0840	transmembrane signaling receptor activity
G3W91_RS17000	COG1619	proteins homologs of microcin C7 resistance protein MccF
G3W91_RS17025	COG4566	intracellular signal transduction
G3W91_RS17030	COG4191	Histidine kinase
G3W91_RS17045	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
G3W91_RS17050	COG1028	Short-chain dehydrogenase reductase Sdr
G3W91_RS17055	COG3246	L-lysine catabolic process to acetate
G3W91_RS17060	COG0410	ABC transporter
G3W91_RS17065	COG0411	ABC transporter
G3W91_RS17075	COG0559	Belongs to the binding-protein-dependent transport system permease family
G3W91_RS17085	COG1028	Short-chain dehydrogenase reductase Sdr
G3W91_RS17095	COG2272	Belongs to the type-B carboxylesterase lipase family
G3W91_RS17110	COG1042	CoA-binding domain protein
G3W91_RS17110	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G3W91_RS17110	COG0045	succinate-CoA ligase (ADP-forming) activity
G3W91_RS17115	COG2197	response regulator
G3W91_RS17130	COG0477	Major facilitator Superfamily
G3W91_RS17135	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
G3W91_RS17140	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
G3W91_RS17145	COG1845	cytochrome c oxidase, subunit III
G3W91_RS17150	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
G3W91_RS17165	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
G3W91_RS17170	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
G3W91_RS17185	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
G3W91_RS17185	COG1672	PFAM Archaeal ATPase
G3W91_RS17190	COG0583	DNA-binding transcription factor activity
G3W91_RS17195	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W91_RS17200	COG1024	Enoyl-CoA hydratase
G3W91_RS17210	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G3W91_RS17210	COG0519	Catalyzes the synthesis of GMP from XMP
G3W91_RS17230	COG2867	negative regulation of translational initiation
G3W91_RS17235	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
G3W91_RS17275	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
G3W91_RS17280	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
G3W91_RS17285	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
G3W91_RS17290	COG2251	uridine kinase activity
G3W91_RS17290	COG0195	Participates in both transcription termination and antitermination
G3W91_RS17295	COG0779	Required for maturation of 30S ribosomal subunits
G3W91_RS17300	COG0477	Major facilitator Superfamily
G3W91_RS17305	COG4172	Belongs to the ABC transporter superfamily
G3W91_RS17310	COG4239	(ABC) transporter, permease
G3W91_RS17315	COG4174	ABC transporter (Permease)
G3W91_RS17320	COG4166	transmembrane transport
G3W91_RS17330	COG1793	dna ligase
G3W91_RS17335	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
G3W91_RS17340	COG1982	Orn Lys Arg decarboxylase major
G3W91_RS17385	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
G3W91_RS17405	COG0583	DNA-binding transcription factor activity
G3W91_RS17410	COG0436	Aminotransferase
G3W91_RS17420	COG1643	Atp-dependent helicase
G3W91_RS17425	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
G3W91_RS17425	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
G3W91_RS17430	COG0436	Aminotransferase
G3W91_RS17435	COG2171	N-acyltransferase activity
G3W91_RS17445	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G3W91_RS17450	COG2890	protein-(glutamine-N5) methyltransferase activity
G3W91_RS17490	COG4670	ketone body catabolic process
G3W91_RS17500	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
G3W91_RS17505	COG0673	inositol 2-dehydrogenase activity
G3W91_RS17515	COG1053	succinate dehydrogenase
G3W91_RS17560	COG3618	amidohydrolase
G3W91_RS17575	COG0411	ABC transporter
G3W91_RS17580	COG0559	Belongs to the binding-protein-dependent transport system permease family
G3W91_RS17590	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W91_RS17595	COG1053	succinate dehydrogenase
G3W91_RS17625	COG1414	Transcriptional regulator
G3W91_RS17635	COG1116	anion transmembrane transporter activity
G3W91_RS17635	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G3W91_RS17640	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3W91_RS17655	COG0439	Biotin carboxylase
G3W91_RS17665	COG3246	L-lysine catabolic process to acetate
G3W91_RS17670	COG1028	Short-chain dehydrogenase reductase Sdr
G3W91_RS17690	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
G3W91_RS17705	COG0823	Involved in the tonB-independent uptake of proteins
G3W91_RS17710	COG1132	(ABC) transporter
G3W91_RS17720	COG1530	ribonuclease E activity
G3W91_RS17725	COG0424	maF-like protein
G3W91_RS17730	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
G3W91_RS17735	COG0799	negative regulation of ribosome biogenesis
G3W91_RS17740	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
G3W91_RS17745	COG0408	coproporphyrinogen oxidase activity
G3W91_RS17750	COG0151	Belongs to the GarS family
G3W91_RS17755	COG0217	transcriptional regulatory protein
G3W91_RS17780	COG1028	Short-chain dehydrogenase reductase Sdr
G3W91_RS17795	COG0726	polysaccharide deacetylase
G3W91_RS17815	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
G3W91_RS17830	COG0433	COG0433 Predicted ATPase
G3W91_RS17835	COG4944	Protein of unknown function (DUF1109)
G3W91_RS17840	COG1595	DNA-templated transcription, initiation
G3W91_RS17850	COG3220	belongs to the UPF0276 family
G3W91_RS17875	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
G3W91_RS17880	COG1744	ABC transporter substrate-binding protein PnrA-like
G3W91_RS17900	COG0402	S-adenosylhomocysteine deaminase activity
G3W91_RS17905	COG2925	Exonuclease
G3W91_RS17910	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G3W91_RS17915	COG0542	response to heat
G3W91_RS17920	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
G3W91_RS17940	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
G3W91_RS17945	COG1570	exodeoxyribonuclease VII activity
G3W91_RS17950	COG0811	peptide transport
G3W91_RS17955	COG0848	biopolymer transport protein
G3W91_RS17960	COG1663	tetraacyldisaccharide 4'-kinase activity
G3W91_RS17965	COG2835	tetraacyldisaccharide 4'-kinase activity
G3W91_RS17970	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
G3W91_RS17975	COG0563	adenylate kinase activity
G3W91_RS17990	COG0252	asparaginase activity
G3W91_RS17995	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
G3W91_RS18005	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G3W91_RS18010	COG2814	Major facilitator Superfamily
G3W91_RS18020	COG1250	3-hydroxyacyl-CoA dehydrogenase
G3W91_RS18025	COG1024	Enoyl-CoA hydratase
G3W91_RS18050	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G3W91_RS18060	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G3W91_RS18065	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
G3W91_RS18070	COG1534	Rna-binding protein
G3W91_RS18085	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G3W91_RS18095	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
G3W91_RS18100	COG0505	Belongs to the CarA family
G3W91_RS18105	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G3W91_RS18110	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
G3W91_RS18115	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G3W91_RS18120	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G3W91_RS18125	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
G3W91_RS18130	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G3W91_RS18145	COG0750	zinc metalloprotease
G3W91_RS18150	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
G3W91_RS18155	COG0575	Belongs to the CDS family
G3W91_RS18160	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
G3W91_RS18165	COG0233	cytoplasmic translational termination
G3W91_RS18170	COG0528	UMP kinase activity
G3W91_RS18175	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
G3W91_RS18180	COG0052	Belongs to the universal ribosomal protein uS2 family
G3W91_RS18190	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G3W91_RS18195	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
G3W91_RS18195	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
G3W91_RS18200	COG1028	Short-chain dehydrogenase reductase Sdr
G3W91_RS18205	COG0557	exoribonuclease II activity
G3W91_RS18215	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
G3W91_RS18220	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
G3W91_RS18235	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G3W91_RS18240	COG1028	Short-chain dehydrogenase reductase Sdr
G3W91_RS18255	COG0745	RESPONSE REGULATOR receiver
G3W91_RS18260	COG2205	protein histidine kinase activity
G3W91_RS18265	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
G3W91_RS18265	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
G3W91_RS18270	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
G3W91_RS18270	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
G3W91_RS18275	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
G3W91_RS18280	COG0560	Phosphoserine phosphatase
G3W91_RS18305	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G3W91_RS18310	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
G3W91_RS18315	COG2079	MmgE PrpD family protein
G3W91_RS18325	COG1024	Enoyl-CoA hydratase
G3W91_RS18345	COG0596	Alpha beta hydrolase
G3W91_RS18360	COG1028	Short-chain dehydrogenase reductase Sdr
G3W91_RS18385	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
G3W91_RS18390	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
G3W91_RS18395	COG1492	cobalamin metabolic process
G3W91_RS18415	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G3W91_RS18430	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
G3W91_RS18435	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
G3W91_RS18440	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
G3W91_RS18445	COG1120	ATPase activity
G3W91_RS18450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G3W91_RS18455	COG4607	ABC-type enterochelin transport system periplasmic component
G3W91_RS18465	COG4206	TonB-dependent receptor
G3W91_RS18480	COG0730	response to heat
G3W91_RS18495	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G3W91_RS18505	COG0318	PFAM AMP-dependent synthetase and ligase
G3W91_RS18525	COG1802	Transcriptional regulator
G3W91_RS18535	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
G3W91_RS18540	COG0583	DNA-binding transcription factor activity
G3W91_RS18545	COG0129	dihydroxy-acid dehydratase activity
G3W91_RS18555	COG0351	phosphomethylpyrimidine kinase
G3W91_RS18570	COG2022	thiamine diphosphate biosynthetic process
G3W91_RS18660	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G3W91_RS18665	COG0642	Histidine kinase
G3W91_RS18670	COG0745	RESPONSE REGULATOR receiver
G3W91_RS18675	COG1414	Transcriptional regulator
G3W91_RS18690	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
G3W91_RS18695	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
G3W91_RS18700	COG1414	Transcriptional regulator
G3W91_RS18710	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G3W91_RS18715	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G3W91_RS18720	COG1183	phosphatidylcholine synthase activity
G3W91_RS18725	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
G3W91_RS18730	COG0440	acetolactate synthase activity
G3W91_RS18735	COG0028	Belongs to the TPP enzyme family
G3W91_RS18770	COG0347	Belongs to the P(II) protein family
G3W91_RS18775	COG0697	spore germination
G3W91_RS18785	COG1028	Short-chain dehydrogenase reductase Sdr
G3W91_RS18790	COG1063	alcohol dehydrogenase
G3W91_RS18795	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
G3W91_RS18835	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G3W91_RS18855	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G3W91_RS18860	COG0596	Alpha beta hydrolase
G3W91_RS18870	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W91_RS18895	COG0235	Class ii aldolase
G3W91_RS18905	COG1012	belongs to the aldehyde dehydrogenase family
G3W91_RS18910	COG3181	Tripartite tricarboxylate transporter family receptor
G3W91_RS18925	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
G3W91_RS19100	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
G3W91_RS19105	COG0746	molybdenum cofactor guanylyltransferase activity
G3W91_RS19120	COG0328	RNA-DNA hybrid ribonuclease activity
G3W91_RS19130	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G3W91_RS19135	COG0741	lytic transglycosylase activity
G3W91_RS19135	COG1388	LysM domain
G3W91_RS19140	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3W91_RS19150	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G3W91_RS19160	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
G3W91_RS19165	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
G3W91_RS19170	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
G3W91_RS19195	COG1074	ATP-dependent DNA helicase activity
G3W91_RS19205	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
G3W91_RS19210	COG0673	inositol 2-dehydrogenase activity
G3W91_RS19215	COG0254	rRNA binding
G3W91_RS19225	COG0534	Mate efflux family protein
G3W91_RS19230	COG5002	protein histidine kinase activity
G3W91_RS19245	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
G3W91_RS19250	COG0581	inorganic phosphate transmembrane transporter activity
G3W91_RS19255	COG0573	inorganic phosphate transmembrane transporter activity
G3W91_RS19260	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
G3W91_RS19265	COG0248	Ppx GppA phosphatase
G3W91_RS19285	COG3634	alkyl hydroperoxide reductase activity
G3W91_RS19290	COG0625	glutathione transferase activity
G3W91_RS19315	COG1960	acyl-CoA dehydrogenase activity
G3W91_RS19320	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
G3W91_RS19330	COG2323	membrane
G3W91_RS19345	COG1024	Enoyl-CoA hydratase
G3W91_RS19355	COG1028	Short-chain dehydrogenase reductase Sdr
G3W91_RS19360	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W91_RS19365	COG3181	Tripartite tricarboxylate transporter family receptor
G3W91_RS19385	COG0589	response to stress
G3W91_RS19400	COG1846	Transcriptional regulator
G3W91_RS19400	COG0456	acetyltransferase
G3W91_RS19405	COG1028	Short-chain dehydrogenase reductase Sdr
G3W91_RS19425	COG1295	ribonuclease BN
G3W91_RS19440	COG0667	Aldo Keto reductase
G3W91_RS19465	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G3W91_RS19470	COG1136	(ABC) transporter
G3W91_RS19485	COG0626	cystathionine gamma-synthase activity
G3W91_RS19500	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
G3W91_RS19505	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
G3W91_RS19515	COG0330	HflC and HflK could
G3W91_RS19520	COG0330	HflC and HflK could
G3W91_RS19525	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
G3W91_RS19530	COG1923	regulation of RNA biosynthetic process
G3W91_RS19535	COG1160	GTP binding
G3W91_RS19540	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G3W91_RS19550	COG0124	histidyl-tRNA synthetase
G3W91_RS19555	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
G3W91_RS19570	COG0820	rRNA (adenine-C2-)-methyltransferase activity
G3W91_RS19575	COG0105	UTP biosynthetic process
G3W91_RS19580	COG1187	pseudouridine synthase activity
G3W91_RS19585	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
G3W91_RS19590	COG0564	pseudouridine synthase activity
G3W91_RS19600	COG1199	ATP-dependent helicase activity
G3W91_RS19620	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
G3W91_RS19625	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G3W91_RS19630	COG0508	dehydrogenase complex catalyzes the overall conversion of
G3W91_RS19635	COG0567	Dehydrogenase, E1 component
G3W91_RS19655	COG1012	belongs to the aldehyde dehydrogenase family
G3W91_RS19685	COG0163	prenyltransferase activity
G3W91_RS19690	COG1250	3-hydroxyacyl-CoA dehydrogenase
G3W91_RS19690	COG1024	Enoyl-CoA hydratase
G3W91_RS19700	COG0477	Major facilitator Superfamily
G3W91_RS19720	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G3W91_RS19725	COG0745	RESPONSE REGULATOR receiver
G3W91_RS19730	COG0784	Response regulator, receiver
G3W91_RS19730	COG2205	protein histidine kinase activity
G3W91_RS19730	COG5002	protein histidine kinase activity
G3W91_RS19740	COG5002	protein histidine kinase activity
G3W91_RS19740	COG5001	Diguanylate cyclase
G3W91_RS19750	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
G3W91_RS19785	COG4608	Belongs to the ABC transporter superfamily
G3W91_RS19795	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G3W91_RS19800	COG0601	transmembrane transport
G3W91_RS19825	COG4792	protein secretion
G3W91_RS19885	COG4789	Type iii secretion
G3W91_RS19900	COG0604	alcohol dehydrogenase
G3W91_RS19915	COG2814	Major facilitator Superfamily
G3W91_RS19925	COG0604	alcohol dehydrogenase
G3W91_RS19925	COG3321	synthase
G3W91_RS19925	COG1028	Short-chain dehydrogenase reductase Sdr
G3W91_RS19940	COG0179	Fumarylacetoacetate (FAA) hydrolase
G3W91_RS19985	COG0633	Ferredoxin
G3W91_RS19995	COG0683	leucine binding
G3W91_RS20010	COG0411	ABC transporter
G3W91_RS20015	COG0410	ABC transporter
G3W91_RS20030	COG0066	3-isopropylmalate dehydratase activity
G3W91_RS20035	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
G3W91_RS20045	COG2188	Transcriptional regulator
G3W91_RS20065	COG3181	Tripartite tricarboxylate transporter family receptor
G3W91_RS20085	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
G3W91_RS20090	COG0318	PFAM AMP-dependent synthetase and ligase
G3W91_RS20095	COG1802	Transcriptional regulator
G3W91_RS20105	COG1116	anion transmembrane transporter activity
G3W91_RS20110	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3W91_RS20135	COG1360	Flagellar Motor Protein
G3W91_RS20155	COG0473	3-isopropylmalate dehydrogenase activity
G3W91_RS20160	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
G3W91_RS20170	COG2133	pyrroloquinoline quinone binding
G3W91_RS20175	COG0791	NLP P60 protein
G3W91_RS20180	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G3W91_RS20185	COG0508	dehydrogenase complex catalyzes the overall conversion of
G3W91_RS20190	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
G3W91_RS20195	COG4191	Histidine kinase
G3W91_RS20200	COG4566	intracellular signal transduction
G3W91_RS20205	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
G3W91_RS20220	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
G3W91_RS20225	COG0167	dihydroorotate dehydrogenase activity
G3W91_RS20240	COG0579	oxidoreductase
G3W91_RS20265	COG0443	Heat shock 70 kDa protein
G3W91_RS20280	COG0822	iron-sulfur transferase activity
G3W91_RS20285	COG1104	cysteine desulfurase activity
G3W91_RS20290	COG1959	2 iron, 2 sulfur cluster binding
G3W91_RS20295	COG0556	nucleotide-excision repair
G3W91_RS20310	COG2878	Part of a membrane complex involved in electron transport
G3W91_RS20325	COG4770	biotin carboxylase activity
G3W91_RS20330	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G3W91_RS20335	COG1703	isobutyryl-CoA mutase activity
G3W91_RS20340	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G3W91_RS20340	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G3W91_RS20345	COG1802	Transcriptional regulator
G3W91_RS20365	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
G3W91_RS20370	COG1201	RNA secondary structure unwinding
G3W91_RS20375	COG0745	RESPONSE REGULATOR receiver
G3W91_RS20415	COG4651	solute:proton antiporter activity
G3W91_RS20415	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
G3W91_RS20420	COG1028	Short-chain dehydrogenase reductase Sdr
G3W91_RS20430	COG0183	Belongs to the thiolase family
G3W91_RS20435	COG3243	poly(R)-hydroxyalkanoic acid synthase
G3W91_RS20465	COG3045	CreA protein
G3W91_RS20480	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G3W91_RS20495	COG0583	DNA-binding transcription factor activity
G3W91_RS20500	COG3622	Belongs to the hyi family
G3W91_RS20510	COG3181	Tripartite tricarboxylate transporter family receptor
G3W91_RS20550	COG0583	DNA-binding transcription factor activity
G3W91_RS20555	COG1028	Short-chain dehydrogenase reductase Sdr
G3W91_RS20600	COG0446	pyridine nucleotide-disulphide oxidoreductase
G3W91_RS20620	COG0583	DNA-binding transcription factor activity
G3W91_RS20640	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G3W91_RS20675	COG2197	response regulator
G3W91_RS20680	COG2197	response regulator
G3W91_RS20700	COG2205	protein histidine kinase activity
G3W91_RS20700	COG0784	Response regulator, receiver
G3W91_RS20710	COG0583	DNA-binding transcription factor activity
G3W91_RS20740	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
G3W91_RS20745	COG2207	Transcriptional regulator
G3W91_RS20755	COG0625	glutathione transferase activity
G3W91_RS20770	COG1741	Belongs to the pirin family
G3W91_RS20795	COG0625	glutathione transferase activity
G3W91_RS20830	COG2353	YceI-like domain
G3W91_RS20835	COG1764	response to oxidative stress
G3W91_RS20840	COG0753	catalase activity
G3W91_RS20845	COG0583	DNA-binding transcription factor activity
G3W91_RS20850	COG1028	Short-chain dehydrogenase reductase Sdr
G3W91_RS20860	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
G3W91_RS20860	COG2755	lipolytic protein G-D-S-L family
G3W91_RS20885	COG1960	acyl-CoA dehydrogenase activity
G3W91_RS20895	COG0596	Alpha beta hydrolase
G3W91_RS20940	COG2309	aminopeptidase activity
G3W91_RS20945	COG1335	isochorismatase
G3W91_RS20955	COG0559	Belongs to the binding-protein-dependent transport system permease family
G3W91_RS20975	COG0583	DNA-binding transcription factor activity
G3W91_RS20980	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G3W91_RS20985	COG3181	Tripartite tricarboxylate transporter family receptor
G3W91_RS20990	COG3181	Tripartite tricarboxylate transporter family receptor
G3W91_RS21000	COG1024	Enoyl-CoA hydratase
G3W91_RS21005	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W91_RS21020	COG0183	Belongs to the thiolase family
G3W91_RS21040	COG2207	Transcriptional regulator
G3W91_RS21045	COG1289	transmembrane transporter activity
G3W91_RS21055	COG1566	PFAM secretion protein HlyD family protein
G3W91_RS21095	COG0318	PFAM AMP-dependent synthetase and ligase
G3W91_RS21100	COG3181	Tripartite tricarboxylate transporter family receptor
G3W91_RS21105	COG1960	acyl-CoA dehydrogenase activity
G3W91_RS21110	COG1960	acyl-CoA dehydrogenase activity
G3W91_RS21115	COG1028	Short-chain dehydrogenase reductase Sdr
G3W91_RS21120	COG2030	dehydratase
G3W91_RS21140	COG0596	Alpha beta hydrolase
G3W91_RS21145	COG2309	aminopeptidase activity
G3W91_RS21150	COG1414	Transcriptional regulator
G3W91_RS21155	COG3181	Tripartite tricarboxylate transporter family receptor
G3W91_RS21185	COG1335	isochorismatase
G3W91_RS21215	COG0318	PFAM AMP-dependent synthetase and ligase
G3W91_RS21225	COG0583	DNA-binding transcription factor activity
G3W91_RS21235	COG1024	Enoyl-CoA hydratase
G3W91_RS21255	COG0776	regulation of translation
G3W91_RS21265	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
G3W91_RS21270	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
G3W91_RS21275	COG0291	Belongs to the bacterial ribosomal protein bL35 family
G3W91_RS21280	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
G3W91_RS21285	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
G3W91_RS21300	COG2224	Isocitrate lyase
G3W91_RS21325	COG1309	transcriptional regulator
G3W91_RS21335	COG0673	inositol 2-dehydrogenase activity
G3W91_RS21390	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
G3W91_RS21420	COG0659	secondary active sulfate transmembrane transporter activity
G3W91_RS21440	COG0542	response to heat
G3W91_RS21460	COG0583	DNA-binding transcription factor activity
G3W91_RS21465	COG3181	Tripartite tricarboxylate transporter family receptor
G3W91_RS21470	COG0314	molybdopterin synthase activity
G3W91_RS21480	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
G3W91_RS21485	COG0303	'Molybdopterin
G3W91_RS21490	COG1763	Mo-molybdopterin cofactor biosynthetic process
G3W91_RS21495	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
G3W91_RS21505	COG0436	Aminotransferase
G3W91_RS21515	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
G3W91_RS21520	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
G3W91_RS21535	COG0305	Participates in initiation and elongation during chromosome replication
G3W91_RS21540	COG0359	binds to the 23S rRNA
G3W91_RS21545	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
G3W91_RS21550	COG2965	DNA replication, synthesis of RNA primer
G3W91_RS21555	COG0360	Binds together with S18 to 16S ribosomal RNA
G3W91_RS21570	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
G3W91_RS21575	COG3634	alkyl hydroperoxide reductase activity
G3W91_RS21615	COG3193	protein, possibly involved in utilization of glycolate and propanediol
G3W91_RS21620	COG0670	Belongs to the BI1 family
G3W91_RS21625	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
G3W91_RS21640	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
G3W91_RS21645	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
G3W91_RS21665	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G3W91_RS21680	COG0473	3-isopropylmalate dehydrogenase activity
G3W91_RS21685	COG0596	Alpha beta hydrolase
G3W91_RS21690	COG0583	DNA-binding transcription factor activity
G3W91_RS21745	COG0322	excinuclease ABC activity
G3W91_RS21755	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
G3W91_RS21760	COG1611	Belongs to the LOG family
G3W91_RS21775	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G3W91_RS21785	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
G3W91_RS21790	COG3237	CsbD-like
G3W91_RS21805	COG0123	including yeast histone deacetylase and acetoin utilization protein
G3W91_RS21820	COG1295	ribonuclease BN
G3W91_RS21820	COG1959	2 iron, 2 sulfur cluster binding
G3W91_RS21835	COG2814	Major facilitator Superfamily
G3W91_RS21850	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W91_RS21855	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G3W91_RS21865	COG0583	DNA-binding transcription factor activity
G3W91_RS21870	COG2910	NAD(P)H-binding
G3W91_RS21915	COG1802	Transcriptional regulator
G3W91_RS21925	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
G3W91_RS21935	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G3W91_RS21955	COG1012	belongs to the aldehyde dehydrogenase family
G3W91_RS21960	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G3W91_RS21970	COG2186	Transcriptional regulator
G3W91_RS21975	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G3W91_RS21985	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G3W91_RS22000	COG2721	sulfolactate sulfo-lyase activity
G3W91_RS22005	COG1028	Short-chain dehydrogenase reductase Sdr
G3W91_RS22010	COG3181	Tripartite tricarboxylate transporter family receptor
G3W91_RS22015	COG0688	phosphatidylethanolamine metabolic process
G3W91_RS22030	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
G3W91_RS22035	COG0443	Heat shock 70 kDa protein
G3W91_RS22040	COG0484	heat shock protein binding
G3W91_RS22045	COG2186	Transcriptional regulator
G3W91_RS22050	COG0179	Fumarylacetoacetate (FAA) hydrolase
G3W91_RS22060	COG2766	serine protein kinase
G3W91_RS22065	COG2718	Belongs to the UPF0229 family
G3W91_RS22070	COG2719	SpoVR family
G3W91_RS22075	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W91_RS22105	COG2818	Glycosylase
G3W91_RS22110	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
G3W91_RS22115	COG1609	Transcriptional regulator
G3W91_RS22130	COG2186	Transcriptional regulator
G3W91_RS22150	COG0625	glutathione transferase activity
G3W91_RS22185	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G3W91_RS22205	COG1538	Outer membrane efflux protein
G3W91_RS22225	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
G3W91_RS22235	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G3W91_RS22250	COG2267	carboxylic ester hydrolase activity
G3W91_RS22255	COG0702	epimerase
G3W91_RS22260	COG3118	belongs to the thioredoxin family
G3W91_RS22265	COG1295	ribonuclease BN
G3W91_RS22275	COG0277	FAD linked oxidase domain protein
G3W91_RS22305	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
G3W91_RS22340	COG1396	sequence-specific DNA binding
G3W91_RS22340	COG3800	Transcriptional regulator
G3W91_RS22350	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
G3W91_RS22415	COG0708	Exodeoxyribonuclease III
G3W91_RS22430	COG3852	Histidine kinase
G3W91_RS22440	COG0174	glutamine synthetase
G3W91_RS22445	COG1546	Belongs to the CinA family
G3W91_RS22445	COG1058	Belongs to the CinA family
G3W91_RS22480	COG4797	methyltransferase
G3W91_RS22480	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G3W91_RS22500	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G3W91_RS22520	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
G3W91_RS22530	COG0287	Prephenate dehydrogenase
G3W91_RS22535	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
G3W91_RS22555	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
G3W91_RS22580	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
G3W91_RS22585	COG2111	Na H antiporter
G3W91_RS22585	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
G3W91_RS22590	COG1006	Multisubunit Na H antiporter MnhC subunit
G3W91_RS22595	COG0651	ATP synthesis coupled electron transport
G3W91_RS22605	COG2212	antiporter activity
G3W91_RS22610	COG1320	monovalent cation:proton antiporter activity
G3W91_RS22655	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G3W91_RS22655	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G3W91_RS22705	COG3608	succinylglutamate desuccinylase aspartoacylase
G3W91_RS22705	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
G3W91_RS22720	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
G3W91_RS22750	COG1027	Aspartate ammonia-lyase
G3W91_RS22755	COG2311	Membrane
G3W91_RS22770	COG3585	molybdate ion transport
G3W91_RS22770	COG2005	Transcriptional regulator
G3W91_RS22785	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
G3W91_RS22795	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
G3W91_RS22800	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G3W91_RS22805	COG1522	sequence-specific DNA binding
G3W91_RS22865	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G3W91_RS22870	COG2151	metal-sulfur cluster biosynthetic enzyme
G3W91_RS22875	COG3396	Phenylacetate-CoA oxygenase
G3W91_RS22880	COG3460	Phenylacetate-CoA oxygenase
G3W91_RS22885	COG3396	Phenylacetate-CoA oxygenase
G3W91_RS22895	COG2050	protein possibly involved in aromatic compounds catabolism
G3W91_RS22900	COG1024	Enoyl-CoA hydratase
G3W91_RS22910	COG1309	transcriptional regulator
G3W91_RS22915	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G3W91_RS22935	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
G3W91_RS22940	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
G3W91_RS22950	COG1722	exodeoxyribonuclease VII activity
G3W91_RS22990	COG3360	Dodecin
G3W91_RS23005	COG0412	Dienelactone hydrolase
G3W91_RS23015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G3W91_RS23045	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
G3W91_RS23055	COG0210	DNA helicase
G3W91_RS23070	COG0516	GMP reductase activity
G3W91_RS23080	COG0300	oxidoreductase activity
G3W91_RS23085	COG0183	Belongs to the thiolase family
G3W91_RS23100	COG0513	Belongs to the DEAD box helicase family
G3W91_RS23105	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
G3W91_RS23110	COG0501	Belongs to the peptidase M48B family
G3W91_RS23115	COG2154	pterin-4-alpha-carbinolamine dehydratase
G3W91_RS23120	COG1162	GTPase activity
G3W91_RS23125	COG0438	transferase activity, transferring glycosyl groups
G3W91_RS23130	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
G3W91_RS23135	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
G3W91_RS23145	COG0335	large ribosomal subunit rRNA binding
G3W91_RS23150	COG0336	Belongs to the RNA methyltransferase TrmD family
G3W91_RS23155	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
G3W91_RS23160	COG0228	four-way junction DNA binding
G3W91_RS23175	COG0306	phosphate transporter
G3W91_RS23180	COG1392	Phosphate transport regulator
G3W91_RS23190	COG0617	tRNA 3'-terminal CCA addition
G3W91_RS23195	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
G3W91_RS23200	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
G3W91_RS23205	COG0628	permease
G3W91_RS23220	COG0438	transferase activity, transferring glycosyl groups
G3W91_RS23240	COG0728	peptidoglycan biosynthetic process
G3W91_RS23245	COG0268	Binds directly to 16S ribosomal RNA
G3W91_RS23255	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G3W91_RS23260	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
G3W91_RS23265	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
G3W91_RS23275	COG3483	tryptophan 2,3-dioxygenase activity
G3W91_RS23285	COG3181	Tripartite tricarboxylate transporter family receptor
G3W91_RS23320	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G3W91_RS23345	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
G3W91_RS23375	COG4106	trans-aconitate 2-methyltransferase activity
G3W91_RS23380	COG0039	L-malate dehydrogenase activity
G3W91_RS23385	COG2188	Transcriptional regulator
G3W91_RS23400	COG1053	succinate dehydrogenase
G3W91_RS23405	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
G3W91_RS23410	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
G3W91_RS23415	COG0372	Belongs to the citrate synthase family
G3W91_RS23430	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
G3W91_RS23435	COG0066	3-isopropylmalate dehydratase activity
G3W91_RS23440	COG0473	3-isopropylmalate dehydrogenase activity
G3W91_RS23445	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
G3W91_RS23455	COG0101	tRNA pseudouridine synthase activity
G3W91_RS23460	COG0135	phosphoribosylanthranilate isomerase activity
G3W91_RS23465	COG0133	tryptophan synthase activity
G3W91_RS23470	COG0159	tryptophan synthase activity
G3W91_RS23475	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
G3W91_RS23480	COG0762	integral membrane protein
G3W91_RS23490	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
G3W91_RS23495	COG0443	Heat shock 70 kDa protein
G3W91_RS23500	COG1451	nucleotide metabolic process
G3W91_RS23505	COG1472	Belongs to the glycosyl hydrolase 3 family
G3W91_RS23510	COG0736	holo-[acyl-carrier-protein] synthase activity
G3W91_RS23515	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
G3W91_RS23520	COG1381	Involved in DNA repair and RecF pathway recombination
G3W91_RS23525	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
G3W91_RS23530	COG0571	ribonuclease III activity
G3W91_RS23540	COG0681	Belongs to the peptidase S26 family
G3W91_RS23545	COG0481	GTPase activity
G3W91_RS23550	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G3W91_RS23570	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G3W91_RS23575	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G3W91_RS23580	COG1028	Short-chain dehydrogenase reductase Sdr
G3W91_RS23585	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
G3W91_RS23590	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G3W91_RS23595	COG0416	fatty acid biosynthetic process
G3W91_RS23600	COG0333	Belongs to the bacterial ribosomal protein bL32 family
G3W91_RS23605	COG1399	metal-binding, possibly nucleic acid-binding protein
G3W91_RS23610	COG0424	maF-like protein
G3W91_RS23615	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
G3W91_RS23620	COG2223	nitrite transmembrane transporter activity
G3W91_RS23625	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
G3W91_RS23625	COG0616	signal peptide processing
G3W91_RS23640	COG0564	pseudouridine synthase activity
G3W91_RS23645	COG1530	ribonuclease E activity
G3W91_RS23660	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G3W91_RS23680	COG0297	glycogen (starch) synthase activity
G3W91_RS23685	COG3206	protein involved in exopolysaccharide biosynthesis
G3W91_RS23685	COG0489	protein tyrosine kinase activity
G3W91_RS23690	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G3W91_RS23715	COG0181	hydroxymethylbilane synthase activity
G3W91_RS23720	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
G3W91_RS23725	COG0583	DNA-binding transcription factor activity
G3W91_RS23730	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
G3W91_RS23770	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
G3W91_RS23770	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
G3W91_RS23785	COG3022	response to hydroperoxide
G3W91_RS23790	COG0525	valine-tRNA ligase activity
G3W91_RS23805	COG0425	Belongs to the sulfur carrier protein TusA family
G3W91_RS23825	COG0724	RNA recognition motif
G3W91_RS23850	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G3W91_RS23890	COG0559	Belongs to the binding-protein-dependent transport system permease family
G3W91_RS23895	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
G3W91_RS23900	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
G3W91_RS23905	COG1674	ftsk spoiiie
G3W91_RS23915	COG0492	ferredoxin-NADP+ reductase activity
G3W91_RS23920	COG0227	Belongs to the bacterial ribosomal protein bL28 family
G3W91_RS23925	COG0267	Belongs to the bacterial ribosomal protein bL33 family
G3W91_RS23935	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
G3W91_RS23935	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
G3W91_RS23955	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
G3W91_RS23960	COG1960	acyl-CoA dehydrogenase activity
G3W91_RS23965	COG1960	acyl-CoA dehydrogenase activity
G3W91_RS23975	COG1024	Enoyl-CoA hydratase
G3W91_RS23985	COG0196	riboflavin kinase activity
G3W91_RS23995	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
G3W91_RS24000	COG1283	sodium-dependent phosphate transmembrane transporter activity
G3W91_RS24015	COG0402	S-adenosylhomocysteine deaminase activity
G3W91_RS24020	COG0402	S-adenosylhomocysteine deaminase activity
G3W91_RS24025	COG4608	Belongs to the ABC transporter superfamily
G3W91_RS24030	COG0444	Belongs to the ABC transporter superfamily
G3W91_RS24040	COG0402	S-adenosylhomocysteine deaminase activity
G3W91_RS24045	COG0747	negative chemotaxis
G3W91_RS24055	COG1028	Short-chain dehydrogenase reductase Sdr
G3W91_RS24065	COG0405	Gamma-glutamyltransferase
G3W91_RS24085	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
G3W91_RS24090	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
G3W91_RS24105	COG0084	hydrolase, TatD family'
G3W91_RS24110	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G3W91_RS24115	COG0714	Associated with various cellular activities
G3W91_RS24125	COG2304	oxidoreductase activity
G3W91_RS24130	COG1028	Short-chain dehydrogenase reductase Sdr
G3W91_RS24135	COG0583	DNA-binding transcription factor activity
G3W91_RS24140	COG3181	Tripartite tricarboxylate transporter family receptor
G3W91_RS24145	COG0445	tRNA wobble uridine modification
G3W91_RS24170	COG3550	peptidyl-serine autophosphorylation
G3W91_RS24180	COG1136	(ABC) transporter
G3W91_RS24195	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
G3W91_RS24225	COG0831	urea catabolic process
G3W91_RS24235	COG0832	Belongs to the urease beta subunit family
G3W91_RS24240	COG0804	urea catabolic process
G3W91_RS24250	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
G3W91_RS24255	COG0830	nickel cation binding
G3W91_RS24260	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
G3W91_RS24270	COG0028	Belongs to the TPP enzyme family
G3W91_RS24320	COG0635	Involved in the biosynthesis of porphyrin-containing compound
G3W91_RS24325	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
G3W91_RS24330	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
G3W91_RS24340	COG0515	serine threonine protein kinase
G3W91_RS24340	COG2815	serine threonine protein kinase
G3W91_RS24345	COG1561	YicC-like family, N-terminal region
G3W91_RS24350	COG0194	GDP metabolic process
G3W91_RS24355	COG1758	RNA polymerase activity
G3W91_RS24360	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G3W91_RS24555	COG0358	DNA primase activity
G3W91_RS24625	COG0328	RNA-DNA hybrid ribonuclease activity
G3W91_RS24645	COG2084	Dehydrogenase
G3W91_RS24700	COG1126	abc transporter atp-binding protein
G3W91_RS24710	COG0765	amino acid transport
G3W91_RS24715	COG0765	amino acid transport
G3W91_RS25150	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
G3W91_RS25160	COG3181	Tripartite tricarboxylate transporter family receptor
G3W91_RS25205	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
G3W91_RS25210	COG1061	Type III restriction enzyme res subunit
G3W91_RS25215	COG1002	Type II restriction enzyme, methylase subunits
G3W91_RS25235	COG1420	regulation of RNA biosynthetic process
G3W91_RS25240	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
G3W91_RS25245	COG0497	DNA recombination
G3W91_RS25250	COG1660	Displays ATPase and GTPase activities
G3W91_RS25260	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
G3W91_RS25265	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
G3W91_RS25280	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
G3W91_RS25290	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
G3W91_RS25295	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
G3W91_RS25300	COG0193	aminoacyl-tRNA hydrolase activity
G3W91_RS25310	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
G3W91_RS25320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G3W91_RS25330	COG4608	Belongs to the ABC transporter superfamily
G3W91_RS25335	COG0747	negative chemotaxis
G3W91_RS25340	COG0154	amidase activity
G3W91_RS25345	COG0583	DNA-binding transcription factor activity
G3W91_RS25375	COG0588	phosphoglycerate mutase activity
G3W91_RS25380	COG2267	carboxylic ester hydrolase activity
G3W91_RS25390	COG0508	dehydrogenase complex catalyzes the overall conversion of
G3W91_RS25395	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G3W91_RS25400	COG0596	Alpha beta hydrolase
G3W91_RS25405	COG0280	phosphate acetyltransferase
G3W91_RS25405	COG0281	malic enzyme
G3W91_RS25410	COG1301	dicarboxylic acid transport
G3W91_RS25415	COG1252	NADH dehydrogenase
G3W91_RS25420	COG0183	Belongs to the thiolase family
G3W91_RS25425	COG1028	Short-chain dehydrogenase reductase Sdr
G3W91_RS25440	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
G3W91_RS25445	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
G3W91_RS25450	COG1984	allophanate hydrolase subunit 2
G3W91_RS25455	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
G3W91_RS25460	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
G3W91_RS25465	COG0742	ribosomal rna small subunit methyltransferase
G3W91_RS25470	COG0612	Peptidase, M16
G3W91_RS25475	COG0612	Peptidase, M16
G3W91_RS25490	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
G3W91_RS25495	COG1999	signal sequence binding
G3W91_RS25500	COG0109	protoheme IX farnesyltransferase activity
G3W91_RS25535	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
G3W91_RS25540	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
G3W91_RS25545	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
G3W91_RS25555	COG2226	methyltransferase
G3W91_RS25565	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
G3W91_RS25575	COG0489	protein tyrosine kinase activity
G3W91_RS25595	COG1024	Enoyl-CoA hydratase
G3W91_RS25620	COG1960	acyl-CoA dehydrogenase activity
G3W91_RS25645	COG1690	Belongs to the RtcB family
G3W91_RS25650	COG2423	ornithine cyclodeaminase activity
G3W91_RS25655	COG0183	Belongs to the thiolase family
G3W91_RS25660	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
G3W91_RS25670	COG1414	Transcriptional regulator
G3W91_RS25690	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G3W91_RS25705	COG2175	clavaminate synthase activity
G3W91_RS25715	COG3246	L-lysine catabolic process to acetate
G3W91_RS25725	COG1414	Transcriptional regulator
G3W91_RS25730	COG3181	Tripartite tricarboxylate transporter family receptor
G3W91_RS25735	COG0179	Fumarylacetoacetate (FAA) hydrolase
G3W91_RS25740	COG3181	Tripartite tricarboxylate transporter family receptor
G3W91_RS25745	COG2175	clavaminate synthase activity
G3W91_RS25755	COG0028	Belongs to the TPP enzyme family
G3W91_RS25760	COG3246	L-lysine catabolic process to acetate
G3W91_RS25790	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
G3W91_RS25795	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G3W91_RS25815	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
G3W91_RS25835	COG2149	membrane
G3W91_RS25865	COG0724	RNA recognition motif
G3W91_RS25875	COG1446	asparaginase
G3W91_RS25880	COG4172	Belongs to the ABC transporter superfamily
G3W91_RS25885	COG0747	negative chemotaxis
G3W91_RS25895	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G3W91_RS25970	COG1137	ATPase activity
G3W91_RS25990	COG1012	belongs to the aldehyde dehydrogenase family
G3W91_RS26000	COG3474	cytochrome
G3W91_RS26030	COG0583	DNA-binding transcription factor activity
G3W91_RS26035	COG3485	protocatechuate 3,4-dioxygenase
G3W91_RS26040	COG3485	protocatechuate 3,4-dioxygenase
G3W91_RS26050	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G3W91_RS26090	COG0582	viral genome integration into host DNA
G3W91_RS26200	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
G3W91_RS26225	COG0540	Belongs to the ATCase OTCase family
G3W91_RS26230	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
G3W91_RS26235	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
G3W91_RS26240	COG1678	Uncharacterized ACR, COG1678
G3W91_RS26245	COG0415	Belongs to the DNA photolyase family
G3W91_RS26250	COG0784	Response regulator, receiver
G3W91_RS26250	COG0643	Histidine kinase
G3W91_RS26250	COG2198	Histidine kinase
G3W91_RS26255	COG0840	transmembrane signaling receptor activity
G3W91_RS26275	COG1773	rubredoxin
G3W91_RS26285	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
G3W91_RS26290	COG0138	bifunctional purine biosynthesis protein purh
G3W91_RS26305	COG1238	metal cluster binding
G3W91_RS26310	COG0012	GTP binding
G3W91_RS26315	COG3217	Mosc domain protein beta barrel domain protein
G3W91_RS26315	COG0633	Ferredoxin
G3W91_RS26320	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G3W91_RS26335	COG1024	Enoyl-CoA hydratase
G3W91_RS26375	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
G3W91_RS26390	COG2255	four-way junction helicase activity
G3W91_RS26395	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
G3W91_RS26400	COG2267	carboxylic ester hydrolase activity
G3W91_RS26405	COG2453	phosphatase
G3W91_RS26405	COG0671	phosphoesterase, PA-phosphatase related
G3W91_RS26420	COG4589	Belongs to the CDS family
G3W91_RS26425	COG0632	four-way junction helicase activity
G3W91_RS26430	COG1702	phosphate starvation-inducible protein PhoH
G3W91_RS26435	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
G3W91_RS26440	COG1490	D-aminoacyl-tRNA deacylase activity
G3W91_RS26445	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
G3W91_RS26460	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
G3W91_RS26465	COG0739	heme binding
G3W91_RS26470	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
G3W91_RS26475	COG2814	Major facilitator Superfamily
G3W91_RS26480	COG0316	Belongs to the HesB IscA family
G3W91_RS26485	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
G3W91_RS26490	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
G3W91_RS26495	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
G3W91_RS26500	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
G3W91_RS26515	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
G3W91_RS26520	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
G3W91_RS26550	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
G3W91_RS26555	COG0477	Major facilitator Superfamily
G3W91_RS26580	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G3W91_RS26590	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
G3W91_RS26595	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
G3W91_RS26600	COG0156	8-amino-7-oxononanoate synthase activity
G3W91_RS26615	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
G3W91_RS26625	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G3W91_RS26630	COG0318	PFAM AMP-dependent synthetase and ligase
G3W91_RS26635	COG1960	acyl-CoA dehydrogenase activity
G3W91_RS26650	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G3W91_RS26655	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
G3W91_RS26670	COG3012	SEC-C Motif Domain Protein
G3W91_RS26685	COG1960	acyl-CoA dehydrogenase activity
G3W91_RS26695	COG0183	Belongs to the thiolase family
G3W91_RS26700	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
G3W91_RS26705	COG0288	reversible hydration of carbon dioxide
G3W91_RS26710	COG0789	Transcriptional regulator
G3W91_RS26725	COG0564	pseudouridine synthase activity
G3W91_RS26730	COG2197	response regulator
G3W91_RS26755	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
G3W91_RS26760	COG0751	glycine-tRNA ligase activity
G3W91_RS26765	COG0752	glycyl-tRNA synthetase alpha subunit
G3W91_RS26785	COG0431	NADPH-dependent FMN reductase
G3W91_RS26790	COG0798	PFAM Bile acid sodium symporter
G3W91_RS26810	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
G3W91_RS26830	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3W91_RS26840	COG0815	Transfers the fatty acyl group on membrane lipoproteins
G3W91_RS26870	COG3186	Phenylalanine-4-hydroxylase
G3W91_RS26880	COG0318	PFAM AMP-dependent synthetase and ligase
G3W91_RS26915	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G3W91_RS26920	COG0436	Aminotransferase
G3W91_RS26930	COG0697	spore germination
G3W91_RS26935	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G3W91_RS26940	COG1280	lysine exporter protein (LysE YggA)
G3W91_RS26945	COG0625	glutathione transferase activity
G3W91_RS26950	COG0384	phenazine biosynthesis protein PhzF
G3W91_RS26970	COG3485	protocatechuate 3,4-dioxygenase
G3W91_RS26975	COG3468	outer membrane autotransporter barrel domain protein
G3W91_RS26985	COG1324	tolerance protein
G3W91_RS27030	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G3W91_RS27035	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
G3W91_RS27040	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
G3W91_RS27055	COG0679	Auxin Efflux Carrier
G3W91_RS27060	COG0210	DNA helicase
G3W91_RS27080	COG1053	succinate dehydrogenase
G3W91_RS27130	COG1028	Short-chain dehydrogenase reductase Sdr
G3W91_RS27135	COG2186	Transcriptional regulator
G3W91_RS27140	COG0318	PFAM AMP-dependent synthetase and ligase
G3W91_RS27175	COG3181	Tripartite tricarboxylate transporter family receptor
G3W91_RS27185	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W91_RS27195	COG3181	Tripartite tricarboxylate transporter family receptor
G3W91_RS27210	COG1960	acyl-CoA dehydrogenase activity
G3W91_RS27215	COG1960	acyl-CoA dehydrogenase activity
G3W91_RS27220	COG0318	PFAM AMP-dependent synthetase and ligase
G3W91_RS27230	COG3181	Tripartite tricarboxylate transporter family receptor
G3W91_RS27250	COG0667	Aldo Keto reductase
G3W91_RS27325	COG2030	dehydratase
G3W91_RS27330	COG1024	Enoyl-CoA hydratase
G3W91_RS27335	COG1028	Short-chain dehydrogenase reductase Sdr
G3W91_RS27350	COG1024	Enoyl-CoA hydratase
G3W91_RS27430	COG2204	response regulator
G3W91_RS27435	COG5000	phosphorelay sensor kinase activity
G3W91_RS27445	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
G3W91_RS27445	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
G3W91_RS27455	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
G3W91_RS27460	COG0085	RNA polymerase activity
G3W91_RS27465	COG0222	ribosome binding
G3W91_RS27470	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
G3W91_RS27475	COG0081	regulation of translation
G3W91_RS27480	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
G3W91_RS27490	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
G3W91_RS27500	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
G3W91_RS27520	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
G3W91_RS27525	COG0134	indole-3-glycerol-phosphate synthase activity
G3W91_RS27530	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
G3W91_RS27535	COG1280	lysine exporter protein (LysE YggA)
G3W91_RS27605	COG4638	Rieske (2fe-2S)
G3W91_RS27620	COG1028	Short-chain dehydrogenase reductase Sdr
G3W91_RS27625	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
G3W91_RS27675	COG2313	pseudouridylate synthase activity
G3W91_RS27680	COG0604	alcohol dehydrogenase
G3W91_RS27690	COG1250	3-hydroxyacyl-CoA dehydrogenase
G3W91_RS27700	COG0546	phosphoglycolate phosphatase activity
G3W91_RS27705	COG2197	response regulator
G3W91_RS27715	COG3916	Acyl-homoserine-lactone synthase
G3W91_RS27725	COG3468	outer membrane autotransporter barrel domain protein
G3W91_RS27730	COG0745	RESPONSE REGULATOR receiver
G3W91_RS27800	COG0631	protein serine/threonine phosphatase activity
G3W91_RS27830	COG3501	Rhs element vgr protein
G3W91_RS27835	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G3W91_RS27875	COG0515	serine threonine protein kinase
G3W91_RS27915	COG3210	domain, Protein
G3W91_RS27920	COG2831	hemolysin activation secretion protein
G3W91_RS27925	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
G3W91_RS27930	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
G3W91_RS27945	COG4251	negative regulation of phosphorylation
G3W91_RS27970	COG0018	arginyl-trna synthetase
G3W91_RS27980	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
G3W91_RS27985	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
G3W91_RS27990	COG1137	ATPase activity
G3W91_RS27995	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
G3W91_RS28000	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G3W91_RS28040	COG2197	response regulator
G3W91_RS28065	COG3179	chitinase
G3W91_RS28080	COG0653	protein targeting
G3W91_RS28105	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
G3W91_RS28135	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G3W91_RS28145	COG0583	DNA-binding transcription factor activity
G3W91_RS28155	COG2197	response regulator
G3W91_RS28160	COG2205	protein histidine kinase activity
G3W91_RS28160	COG2198	Histidine kinase
G3W91_RS28160	COG0784	Response regulator, receiver
G3W91_RS28180	COG1396	sequence-specific DNA binding
G3W91_RS28185	COG0235	Class ii aldolase
G3W91_RS28190	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
G3W91_RS28205	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
G3W91_RS28215	COG2967	ApaG domain
G3W91_RS28220	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
G3W91_RS28255	COG2205	protein histidine kinase activity
G3W91_RS28260	COG0745	RESPONSE REGULATOR receiver
G3W91_RS28290	COG2084	Dehydrogenase
G3W91_RS28300	COG4948	Mandelate Racemase Muconate Lactonizing
G3W91_RS28305	COG3181	Tripartite tricarboxylate transporter family receptor
G3W91_RS28310	COG1609	Transcriptional regulator
G3W91_RS28365	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W91_RS28370	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G3W91_RS28375	COG1414	Transcriptional regulator
G3W91_RS28380	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
G3W91_RS28385	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
G3W91_RS28410	COG0583	DNA-binding transcription factor activity
G3W91_RS28420	COG0183	Belongs to the thiolase family
G3W91_RS28425	COG1024	Enoyl-CoA hydratase
G3W91_RS28430	COG1960	acyl-CoA dehydrogenase activity
G3W91_RS28435	COG0583	DNA-binding transcription factor activity
G3W91_RS28450	COG0205	6-phosphofructokinase activity
G3W91_RS28465	COG2814	Major facilitator Superfamily
G3W91_RS28470	COG0121	glutamine amidotransferase
G3W91_RS28480	COG0189	ligase activity
G3W91_RS28485	COG3135	benzoate transporter
G3W91_RS28490	COG3158	transport of potassium into the cell
G3W91_RS28500	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
G3W91_RS28505	COG1466	dna polymerase III delta subunit
G3W91_RS28515	COG0495	leucyl-tRNA aminoacylation
G3W91_RS28530	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
G3W91_RS28535	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G3W91_RS28540	COG0735	belongs to the Fur family
G3W91_RS28545	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
G3W91_RS28555	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
G3W91_RS28560	COG0210	DNA helicase
G3W91_RS28565	COG0598	Magnesium transport protein CorA
G3W91_RS28575	COG0318	PFAM AMP-dependent synthetase and ligase
G3W91_RS28595	COG0745	RESPONSE REGULATOR receiver
G3W91_RS28610	COG0482	sulfurtransferase activity
G3W91_RS28620	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G3W91_RS28640	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
G3W91_RS28650	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
G3W91_RS28660	COG0438	transferase activity, transferring glycosyl groups
G3W91_RS28670	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G3W91_RS28675	COG1596	polysaccharide export
G3W91_RS28680	COG0629	single-stranded DNA binding
G3W91_RS28705	COG1946	Acyl-CoA thioesterase
G3W91_RS28710	COG0446	pyridine nucleotide-disulphide oxidoreductase
G3W91_RS28715	COG3181	Tripartite tricarboxylate transporter family receptor
G3W91_RS28725	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G3W91_RS28740	COG0583	DNA-binding transcription factor activity
G3W91_RS28750	COG3437	response regulator, receiver
G3W91_RS28750	COG3850	Histidine kinase
G3W91_RS28750	COG4999	Histidine kinase
G3W91_RS28750	COG2205	protein histidine kinase activity
G3W91_RS28750	COG2205	protein histidine kinase activity
G3W91_RS28750	COG3437	response regulator, receiver
G3W91_RS28750	COG3850	Histidine kinase
G3W91_RS28750	COG4999	Histidine kinase
G3W91_RS28760	COG0745	RESPONSE REGULATOR receiver
G3W91_RS28765	COG0179	Fumarylacetoacetate (FAA) hydrolase
G3W91_RS28770	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
G3W91_RS28780	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G3W91_RS28830	COG0284	orotidine-5'-phosphate decarboxylase activity
G3W91_RS28860	COG0009	L-threonylcarbamoyladenylate synthase
G3W91_RS28865	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
G3W91_RS28870	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
G3W91_RS28875	COG3118	belongs to the thioredoxin family
G3W91_RS28895	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
G3W91_RS28905	COG0469	pyruvate kinase activity
G3W91_RS28910	COG0126	phosphoglycerate kinase activity
G3W91_RS28915	COG0583	DNA-binding transcription factor activity
G3W91_RS28930	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G3W91_RS28950	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
G3W91_RS28960	COG0242	peptide deformylase activity
G3W91_RS28970	COG0758	DNA mediated transformation
G3W91_RS28975	COG2922	Belongs to the Smg family
G3W91_RS28990	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G3W91_RS28995	COG1862	Preprotein translocase
G3W91_RS29005	COG1522	sequence-specific DNA binding
G3W91_RS29010	COG2814	Major facilitator Superfamily
G3W91_RS29015	COG1959	2 iron, 2 sulfur cluster binding
G3W91_RS29020	COG0644	oxidoreductase
G3W91_RS29050	COG0251	oxidation-reduction process
G3W91_RS29055	COG3622	Belongs to the hyi family
G3W91_RS29060	COG0235	Class ii aldolase
G3W91_RS29065	COG3395	kinase activity
G3W91_RS29070	COG2084	Dehydrogenase
G3W91_RS29090	COG0583	DNA-binding transcription factor activity
G3W91_RS29095	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
G3W91_RS29105	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
G3W91_RS29110	COG0045	succinate-CoA ligase (ADP-forming) activity
G3W91_RS29120	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W91_RS29125	COG4191	Histidine kinase
G3W91_RS29175	COG0513	Belongs to the DEAD box helicase family
G3W91_RS29180	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
G3W91_RS29185	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G3W91_RS29195	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
G3W91_RS29205	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
G3W91_RS29205	COG0551	DNA topoisomerase type I activity
G3W91_RS29215	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
G3W91_RS29215	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
G3W91_RS29225	COG0642	Histidine kinase
G3W91_RS29240	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
G3W91_RS29245	COG2137	regulation of response to DNA damage stimulus
G3W91_RS29250	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
G3W91_RS29255	COG0045	succinate-CoA ligase (ADP-forming) activity
G3W91_RS29260	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
G3W91_RS29265	COG0861	Integral membrane protein TerC family
G3W91_RS29270	COG0631	protein serine/threonine phosphatase activity
G3W91_RS29290	COG4969	Belongs to the N-Me-Phe pilin family
G3W91_RS29300	COG3307	-O-antigen
G3W91_RS29330	COG0438	transferase activity, transferring glycosyl groups
G3W91_RS29335	COG1215	transferase activity, transferring glycosyl groups
G3W91_RS29345	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
G3W91_RS29350	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
G3W91_RS29390	COG0315	cyclic pyranopterin monophosphate synthase activity
G3W91_RS29395	COG4783	chaperone-mediated protein folding
G3W91_RS29400	COG1950	PFAM Membrane protein of
G3W91_RS29410	COG0861	Integral membrane protein TerC family
G3W91_RS29440	COG4269	membrane
G3W91_RS29445	COG0625	glutathione transferase activity
G3W91_RS29460	COG1595	DNA-templated transcription, initiation
G3W91_RS29470	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
G3W91_RS29490	COG4566	intracellular signal transduction
G3W91_RS29520	COG2076	Multidrug Resistance protein
G3W91_RS29525	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
G3W91_RS29525	COG0546	phosphoglycolate phosphatase activity
G3W91_RS29540	COG1522	sequence-specific DNA binding
G3W91_RS29545	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
G3W91_RS29550	COG1309	transcriptional regulator
G3W91_RS29600	COG1058	Belongs to the CinA family
G3W91_RS29600	COG1546	Belongs to the CinA family
G3W91_RS29610	COG1028	Short-chain dehydrogenase reductase Sdr
G3W91_RS29615	COG1295	ribonuclease BN
G3W91_RS29620	COG0583	DNA-binding transcription factor activity
G3W91_RS29625	COG4221	oxidoreductase activity
G3W91_RS29630	COG1028	Short-chain dehydrogenase reductase Sdr
G3W91_RS29635	COG1047	Peptidyl-prolyl cis-trans
G3W91_RS29670	COG0473	3-isopropylmalate dehydrogenase activity
G3W91_RS29675	COG0066	3-isopropylmalate dehydratase activity
G3W91_RS29680	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
G3W91_RS29690	COG0583	DNA-binding transcription factor activity
G3W91_RS29695	COG0583	DNA-binding transcription factor activity
G3W91_RS29705	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G3W91_RS29710	COG3181	Tripartite tricarboxylate transporter family receptor
G3W91_RS29720	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G3W91_RS29730	COG0179	Fumarylacetoacetate (FAA) hydrolase
G3W91_RS29735	COG2198	Histidine kinase
G3W91_RS29735	COG2205	protein histidine kinase activity
G3W91_RS29735	COG0784	Response regulator, receiver
G3W91_RS29740	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
G3W91_RS29755	COG0667	Aldo Keto reductase
G3W91_RS29765	COG3639	organic phosphonate transmembrane transporter activity
G3W91_RS29770	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
G3W91_RS29775	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
G3W91_RS29780	COG1793	dna ligase
G3W91_RS29790	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G3W91_RS29810	COG1477	protein flavinylation
G3W91_RS29825	COG3454	Phosphonate metabolism
G3W91_RS29830	COG4778	phosphonate C-P lyase system protein PhnL
G3W91_RS29835	COG4107	phosphonate C-P lyase system protein PhnK
G3W91_RS29840	COG3627	carbon phosphorus lyase activity
G3W91_RS29845	COG3626	phosphonate metabolism
G3W91_RS29855	COG3624	Phosphonate C-P lyase system protein PhnG
G3W91_RS29860	COG2188	Transcriptional regulator
G3W91_RS29865	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
G3W91_RS29875	COG0583	DNA-binding transcription factor activity
G3W91_RS29880	COG4221	oxidoreductase activity
G3W91_RS29880	COG0604	alcohol dehydrogenase
G3W91_RS29880	COG3321	synthase
G3W91_RS29880	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G3W91_RS29890	COG2202	Pas domain
G3W91_RS29890	COG2205	protein histidine kinase activity
G3W91_RS29900	COG0784	Response regulator, receiver
G3W91_RS29935	COG1295	ribonuclease BN
G3W91_RS29950	COG0384	phenazine biosynthesis protein PhzF
G3W91_RS29965	COG0445	tRNA wobble uridine modification
G3W91_RS30005	COG0523	cobalamin synthesis protein
G3W91_RS30025	COG0179	Fumarylacetoacetate (FAA) hydrolase
G3W91_RS30030	COG0583	DNA-binding transcription factor activity
G3W91_RS30045	COG0477	Major facilitator Superfamily
G3W91_RS30050	COG0583	DNA-binding transcription factor activity
G3W91_RS30075	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G3W91_RS30100	COG0683	leucine binding
G3W91_RS30105	COG1309	transcriptional regulator
G3W91_RS30125	COG0604	alcohol dehydrogenase
G3W91_RS30135	COG0583	DNA-binding transcription factor activity
G3W91_RS30160	COG4977	sequence-specific DNA binding
G3W91_RS30190	COG0583	DNA-binding transcription factor activity
G3W91_RS30195	COG3485	protocatechuate 3,4-dioxygenase
G3W91_RS30205	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W91_RS30235	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
G3W91_RS30245	COG3546	catalase activity
G3W91_RS30285	COG0514	ATP-dependent DNA helicase (RecQ)
G3W91_RS30305	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
G3W91_RS30310	COG5002	protein histidine kinase activity
G3W91_RS30325	COG0730	response to heat
G3W91_RS30330	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W91_RS30335	COG0583	DNA-binding transcription factor activity
G3W91_RS30345	COG0604	alcohol dehydrogenase
G3W91_RS30350	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W91_RS30360	COG1414	Transcriptional regulator
G3W91_RS30365	COG3181	Tripartite tricarboxylate transporter family receptor
G3W91_RS30375	COG1028	Short-chain dehydrogenase reductase Sdr
G3W91_RS30385	COG3181	Tripartite tricarboxylate transporter family receptor
G3W91_RS30415	COG0446	pyridine nucleotide-disulphide oxidoreductase
G3W91_RS30475	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G3W91_RS30485	COG4948	Mandelate Racemase Muconate Lactonizing
G3W91_RS30495	COG0457	Tetratricopeptide repeat
G3W91_RS30495	COG3710	Transcriptional regulator
G3W91_RS30540	COG1960	acyl-CoA dehydrogenase activity
G3W91_RS30545	COG0318	PFAM AMP-dependent synthetase and ligase
G3W91_RS30550	COG0583	DNA-binding transcription factor activity
G3W91_RS30585	COG0277	FAD linked oxidase domain protein
G3W91_RS30585	COG0247	lactate metabolic process
G3W91_RS30595	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
G3W91_RS30615	COG2094	Belongs to the DNA glycosylase MPG family
G3W91_RS30650	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
G3W91_RS30675	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
G3W91_RS30680	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
G3W91_RS30685	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
G3W91_RS30715	COG0006	proline dipeptidase activity
G3W91_RS30735	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
G3W91_RS30755	COG0280	phosphate acetyltransferase
G3W91_RS30755	COG0281	malic enzyme
G3W91_RS30770	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
G3W91_RS30775	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G3W91_RS30780	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
G3W91_RS30790	COG1385	rRNA (uridine-N3-)-methyltransferase activity
G3W91_RS30805	COG2814	Major facilitator Superfamily
G3W91_RS30810	COG2267	carboxylic ester hydrolase activity
G3W91_RS30830	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G3W91_RS30835	COG1739	Uncharacterized protein family UPF0029
G3W91_RS30840	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G3W91_RS30840	COG2813	Specifically methylates the guanine in position
G3W91_RS30845	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G3W91_RS30850	COG2119	membrane
G3W91_RS30855	COG0724	RNA recognition motif
G3W91_RS30860	COG0300	oxidoreductase activity
G3W91_RS30870	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
G3W91_RS30895	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
G3W91_RS30900	COG0706	membrane insertase activity
G3W91_RS30905	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
G3W91_RS30910	COG0594	ribonuclease P activity
G3W91_RS30915	COG0230	Belongs to the bacterial ribosomal protein bL34 family
G3W91_RS30920	COG1192	Involved in chromosome partitioning
G3W91_RS30955	COG1605	Chorismate mutase
G3W91_RS30970	COG1396	sequence-specific DNA binding
G3W91_RS30995	COG0196	riboflavin kinase activity
G3W91_RS31020	COG0778	Nitroreductase
G3W91_RS31030	COG3485	protocatechuate 3,4-dioxygenase
G3W91_RS31050	COG1595	DNA-templated transcription, initiation
G3W91_RS31055	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G3W91_RS31075	COG1074	ATP-dependent DNA helicase activity
G3W91_RS31100	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W91_RS31110	COG0583	DNA-binding transcription factor activity
G3W91_RS31165	COG1028	Short-chain dehydrogenase reductase Sdr
G3W91_RS31170	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G3W91_RS31175	COG2084	Dehydrogenase
G3W91_RS31190	COG1414	Transcriptional regulator
G3W91_RS31220	COG3621	Patatin-like phospholipase
G3W91_RS31225	COG3621	Patatin-like phospholipase
G3W91_RS31235	COG2124	cytochrome p450
G3W91_RS31290	COG1073	alpha beta
G3W91_RS31300	COG0604	alcohol dehydrogenase
G3W91_RS31300	COG3321	synthase
G3W91_RS31300	COG1028	Short-chain dehydrogenase reductase Sdr
G3W91_RS31305	COG0596	Alpha beta hydrolase
G3W91_RS31350	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
G3W91_RS31360	COG1414	Transcriptional regulator
G3W91_RS31370	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G3W91_RS31445	COG1024	Enoyl-CoA hydratase
G3W91_RS31460	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
G3W91_RS31495	COG0277	FAD linked oxidase domain protein
G3W91_RS31500	COG1522	sequence-specific DNA binding
G3W91_RS31530	COG1570	exodeoxyribonuclease VII activity
G3W91_RS31555	COG3181	Tripartite tricarboxylate transporter family receptor
G3W91_RS31565	COG0583	DNA-binding transcription factor activity
G3W91_RS31570	COG1609	Transcriptional regulator
G3W91_RS31585	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W91_RS31590	COG1024	Enoyl-CoA hydratase
G3W91_RS31595	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G3W91_RS31600	COG3181	Tripartite tricarboxylate transporter family receptor
G3W91_RS31615	COG3181	Tripartite tricarboxylate transporter family receptor
G3W91_RS31620	COG3181	Tripartite tricarboxylate transporter family receptor
G3W91_RS31625	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G3W91_RS31760	COG4638	Rieske (2fe-2S)
G3W91_RS31810	COG0210	DNA helicase
G3W91_RS31840	COG1570	exodeoxyribonuclease VII activity
G3W91_RS31910	COG3177	Filamentation induced by cAMP protein fic
G3W91_RS31915	COG0587	DNA-directed DNA polymerase activity
G3W91_RS31985	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G3W91_RS31990	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G3W91_RS32015	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
G3W91_RS32030	COG0789	Transcriptional regulator
G3W91_RS32035	COG0672	)-iron permease
G3W91_RS32060	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G3W91_RS32065	COG0583	DNA-binding transcription factor activity
G3W91_RS32085	COG1959	2 iron, 2 sulfur cluster binding
G3W91_RS32095	COG1074	ATP-dependent DNA helicase activity
G3W91_RS32100	COG3593	DNA synthesis involved in DNA repair
G3W91_RS32135	COG3077	Addiction module antitoxin, RelB DinJ family
G3W91_RS32160	COG2337	Toxic component of a toxin-antitoxin (TA) module
G3W91_RS32165	COG2336	PFAM SpoVT AbrB
G3W91_RS32170	COG3622	Belongs to the hyi family
G3W91_RS32180	COG0583	DNA-binding transcription factor activity
G3W91_RS32185	COG0028	Belongs to the TPP enzyme family
G3W91_RS32190	COG3181	Tripartite tricarboxylate transporter family receptor
G3W91_RS32200	COG3622	Belongs to the hyi family
G3W91_RS32210	COG1028	Short-chain dehydrogenase reductase Sdr
G3W91_RS32210	COG0604	alcohol dehydrogenase
G3W91_RS32210	COG3321	synthase
G3W91_RS32215	COG1028	Short-chain dehydrogenase reductase Sdr
G3W91_RS32225	COG0765	amino acid transport
G3W91_RS32230	COG0765	amino acid transport
G3W91_RS32265	COG1053	succinate dehydrogenase
G3W91_RS32265	COG0431	NADPH-dependent FMN reductase
G3W91_RS32265	COG3976	FMN-binding domain protein
G3W91_RS32275	COG0154	amidase activity
G3W91_RS32285	COG3181	Tripartite tricarboxylate transporter family receptor
G3W91_RS32290	COG0436	Aminotransferase
G3W91_RS32295	COG0583	DNA-binding transcription factor activity
G3W91_RS32315	COG0154	amidase activity
G3W91_RS32345	COG2814	Major facilitator Superfamily
G3W91_RS32365	COG0418	dihydroorotase activity
G3W91_RS32375	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
G3W91_RS32395	COG0243	molybdopterin cofactor binding
G3W91_RS32400	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
G3W91_RS32435	COG0671	phosphoesterase, PA-phosphatase related
G3W91_RS32440	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
G3W91_RS32445	COG2076	Multidrug Resistance protein
G3W91_RS32470	COG0726	polysaccharide deacetylase
G3W91_RS32490	COG0745	RESPONSE REGULATOR receiver
G3W91_RS32535	COG0402	S-adenosylhomocysteine deaminase activity
G3W91_RS32550	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G3W91_RS32565	COG1475	DNA binding
G3W91_RS32590	COG3451	type IV secretory pathway VirB4
G3W91_RS32620	COG3504	Conjugal transfer protein
G3W91_RS32625	COG2948	multi-organism process
G3W91_RS32660	COG4227	nucleotidyltransferase activity
G3W91_RS32675	COG0793	Belongs to the peptidase S41A family
G3W91_RS32675	COG3409	Peptidoglycan-binding domain 1 protein
G3W91_RS32685	COG0402	S-adenosylhomocysteine deaminase activity
G3W91_RS32690	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
G3W91_RS32705	COG0445	tRNA wobble uridine modification
G3W91_RS32770	COG1116	anion transmembrane transporter activity
G3W91_RS32770	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G3W91_RS32775	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3W91_RS32780	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3W91_RS32785	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
G3W91_RS32800	COG2207	Transcriptional regulator
G3W91_RS32805	COG2207	Transcriptional regulator
G3W91_RS32825	COG3177	Filamentation induced by cAMP protein fic
G3W91_RS32835	COG2188	Transcriptional regulator
G3W91_RS32840	COG3181	Tripartite tricarboxylate transporter family receptor
G3W91_RS32850	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G3W91_RS32850	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G3W91_RS32855	COG0066	3-isopropylmalate dehydratase activity
G3W91_RS32860	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
G3W91_RS32875	COG1028	Short-chain dehydrogenase reductase Sdr
G3W91_RS32880	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G3W91_RS32895	COG2963	transposase activity
G3W91_RS32945	COG1522	sequence-specific DNA binding
G3W91_RS32965	COG1126	abc transporter atp-binding protein
G3W91_RS33005	COG3916	Acyl-homoserine-lactone synthase
G3W91_RS33010	COG2197	response regulator
G3W91_RS33040	COG1192	Involved in chromosome partitioning
G3W91_RS33085	COG2805	Type II/IV secretion system protein
G3W91_RS33100	COG0784	Response regulator, receiver
G3W91_RS33100	COG2198	Histidine kinase
G3W91_RS33100	COG5002	protein histidine kinase activity
G3W91_RS33195	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
G3W91_RS33570	COG0116	Belongs to the methyltransferase superfamily
G3W91_RS33740	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G3W91_RS33745	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G3W91_RS33815	COG2217	Heavy metal translocating P-type atpase
G3W91_RS33850	COG0583	DNA-binding transcription factor activity
G3W91_RS33860	COG0626	cystathionine gamma-synthase activity
G3W91_RS33865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G3W91_RS33870	COG0765	amino acid transport
G3W91_RS33875	COG0765	amino acid transport
G3W91_RS33880	COG1126	abc transporter atp-binding protein
G3W91_RS33915	COG3387	PFAM Glycoside hydrolase 15-related
G3W91_RS33970	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G3W91_RS34005	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G3W91_RS34025	COG4716	Myosin-crossreactive antigen
G3W91_RS34035	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
G3W91_RS34040	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
G3W91_RS34045	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
G3W91_RS34145	COG4372	Transposase
G3W91_RS34170	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G3W91_RS34175	COG0318	PFAM AMP-dependent synthetase and ligase
G3W91_RS34175	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G3W91_RS34175	COG0300	oxidoreductase activity
G3W91_RS34175	COG3321	synthase
G3W91_RS34175	COG1028	Short-chain dehydrogenase reductase Sdr
G3W91_RS34230	COG0697	spore germination
G3W91_RS34245	COG0464	growth
G3W91_RS34320	COG1845	cytochrome c oxidase, subunit III
G3W91_RS34325	COG1999	signal sequence binding
G3W91_RS34340	COG1845	cytochrome c oxidase, subunit III
G3W91_RS34535	COG3189	MarR family transcriptional regulator
G3W91_RS34550	COG4191	Histidine kinase
G3W91_RS34555	COG2204	response regulator
G3W91_RS34565	COG0243	molybdopterin cofactor binding
G3W91_RS34565	COG3383	formate dehydrogenase (NAD+) activity
G3W91_RS34570	COG0437	4 iron, 4 sulfur cluster binding
G3W91_RS34610	COG1595	DNA-templated transcription, initiation
G3W91_RS34620	COG3474	cytochrome
G3W91_RS34625	COG1573	uracil-dna glycosylase
G3W91_RS34655	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
G3W91_RS34675	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G3W91_RS34685	COG3041	Addiction module toxin RelE StbE family
G3W91_RS34690	COG3077	Addiction module antitoxin, RelB DinJ family
G3W91_RS34715	COG0187	DNA topoisomerase II activity
G3W91_RS34745	COG0820	rRNA (adenine-C2-)-methyltransferase activity
G3W91_RS34770	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
G3W91_RS34895	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
G3W91_RS34975	COG0675	Transposase, IS605 OrfB family
G3W91_RS35145	COG0305	Participates in initiation and elongation during chromosome replication
G3W91_RS35170	COG2827	Endonuclease containing a URI domain
G3W91_RS35215	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
G3W91_RS35230	COG2974	May be involved in recombination
G3W91_RS35280	COG0557	exoribonuclease II activity
G3W91_RS35365	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
G3W91_RS35385	COG1121	(ABC) transporter
G3W91_RS35465	COG3701	Conjugal transfer protein
G3W91_RS35470	COG3451	type IV secretory pathway VirB4
G3W91_RS35475	COG5268	conjugation
G3W91_RS35480	COG3838	Conjugal transfer protein Trbc
G3W91_RS35485	COG4962	Type ii secretion system protein e