locus-tag	class	description
G3W92_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
G3W92_RS00010	COG0592	DNA-directed DNA polymerase activity
G3W92_RS00030	COG1408	metallophosphoesterase
G3W92_RS00045	COG0392	lysyltransferase activity
G3W92_RS00050	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G3W92_RS00055	COG3568	Endonuclease Exonuclease Phosphatase
G3W92_RS00070	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G3W92_RS00095	COG2205	protein histidine kinase activity
G3W92_RS00100	COG0745	RESPONSE REGULATOR receiver
G3W92_RS00110	COG2608	mercury ion transmembrane transporter activity
G3W92_RS00125	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G3W92_RS00145	COG0745	RESPONSE REGULATOR receiver
G3W92_RS00150	COG0642	Histidine kinase
G3W92_RS00155	COG1902	pentaerythritol trinitrate reductase activity
G3W92_RS00170	COG5487	UPF0391 membrane protein
G3W92_RS00175	COG0445	tRNA wobble uridine modification
G3W92_RS00180	COG0357	Ribosomal RNA small subunit methyltransferase G
G3W92_RS00185	COG1280	lysine exporter protein (LysE YggA)
G3W92_RS00210	COG0277	FAD linked oxidase domain protein
G3W92_RS00215	COG2096	Adenosyltransferase
G3W92_RS00240	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
G3W92_RS00250	COG0850	regulation of cytokinetic process
G3W92_RS00260	COG2233	PERMEase
G3W92_RS00265	COG2050	protein possibly involved in aromatic compounds catabolism
G3W92_RS00285	COG0559	Belongs to the binding-protein-dependent transport system permease family
G3W92_RS00320	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
G3W92_RS00345	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G3W92_RS00350	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G3W92_RS00360	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G3W92_RS00365	COG0583	DNA-binding transcription factor activity
G3W92_RS00405	COG0235	Class ii aldolase
G3W92_RS00415	COG1024	Enoyl-CoA hydratase
G3W92_RS00445	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G3W92_RS00475	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
G3W92_RS00515	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W92_RS00535	COG0740	serine-type endopeptidase activity
G3W92_RS00545	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS00570	COG0477	Major facilitator Superfamily
G3W92_RS00575	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
G3W92_RS00580	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
G3W92_RS00585	COG1845	cytochrome c oxidase, subunit III
G3W92_RS00590	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
G3W92_RS00605	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
G3W92_RS00620	COG0004	ammonium transporteR
G3W92_RS00630	COG2207	Transcriptional regulator
G3W92_RS00635	COG2223	nitrite transmembrane transporter activity
G3W92_RS00645	COG2205	protein histidine kinase activity
G3W92_RS00650	COG4789	Type iii secretion
G3W92_RS00680	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G3W92_RS00685	COG0450	alkyl hydroperoxide reductase
G3W92_RS00690	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G3W92_RS00715	COG0640	Transcriptional regulator
G3W92_RS00725	COG1881	PFAM PEBP family protein
G3W92_RS00735	COG0583	DNA-binding transcription factor activity
G3W92_RS00740	COG1960	acyl-CoA dehydrogenase activity
G3W92_RS00745	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W92_RS00785	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G3W92_RS00790	COG0700	Nucleoside recognition
G3W92_RS00820	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
G3W92_RS00825	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
G3W92_RS00830	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G3W92_RS00845	COG2003	Belongs to the UPF0758 family
G3W92_RS00875	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
G3W92_RS00900	COG1228	amidohydrolase
G3W92_RS00945	COG0725	ABC transporter, periplasmic molybdate-binding protein
G3W92_RS00950	COG4149	molybdate abc transporter
G3W92_RS00970	COG1309	transcriptional regulator
G3W92_RS00980	COG0583	DNA-binding transcription factor activity
G3W92_RS01000	COG0646	methionine synthase
G3W92_RS01000	COG1410	methionine synthase
G3W92_RS01025	COG1309	transcriptional regulator
G3W92_RS01075	COG1335	isochorismatase
G3W92_RS01080	COG2080	2 iron, 2 sulfur cluster binding
G3W92_RS01085	COG1529	Aldehyde oxidase and xanthine dehydrogenase
G3W92_RS01085	COG2010	Cytochrome c
G3W92_RS01095	COG2721	sulfolactate sulfo-lyase activity
G3W92_RS01115	COG4948	Mandelate Racemase Muconate Lactonizing
G3W92_RS01120	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G3W92_RS01130	COG1012	belongs to the aldehyde dehydrogenase family
G3W92_RS01140	COG1126	abc transporter atp-binding protein
G3W92_RS01145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G3W92_RS01155	COG0765	amino acid transport
G3W92_RS01165	COG0606	chelatase, subunit chli
G3W92_RS01175	COG0347	Belongs to the P(II) protein family
G3W92_RS01180	COG0004	ammonium transporteR
G3W92_RS01195	COG0247	lactate metabolic process
G3W92_RS01205	COG0386	Belongs to the glutathione peroxidase family
G3W92_RS01215	COG0477	Major facilitator Superfamily
G3W92_RS01220	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
G3W92_RS01225	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
G3W92_RS01235	COG0129	dihydroxy-acid dehydratase activity
G3W92_RS01245	COG3971	2-oxopent-4-enoate hydratase activity
G3W92_RS01270	COG1012	belongs to the aldehyde dehydrogenase family
G3W92_RS01285	COG1846	Transcriptional regulator
G3W92_RS01320	COG2974	May be involved in recombination
G3W92_RS01350	COG0745	RESPONSE REGULATOR receiver
G3W92_RS01355	COG0579	oxidoreductase
G3W92_RS01415	COG1335	isochorismatase
G3W92_RS01455	COG0583	DNA-binding transcription factor activity
G3W92_RS01470	COG2072	flavoprotein involved in K transport
G3W92_RS01475	COG0708	Exodeoxyribonuclease III
G3W92_RS01480	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
G3W92_RS01490	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
G3W92_RS01495	COG0154	amidase activity
G3W92_RS01500	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
G3W92_RS01505	COG1077	Cell shape determining protein MreB Mrl
G3W92_RS01520	COG0768	penicillin binding
G3W92_RS01530	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G3W92_RS01550	COG0622	Phosphoesterase
G3W92_RS01555	COG2095	MarC family integral membrane protein
G3W92_RS01560	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS01570	COG0412	Dienelactone hydrolase
G3W92_RS01575	COG0583	DNA-binding transcription factor activity
G3W92_RS01590	COG0598	Magnesium transport protein CorA
G3W92_RS01610	COG3411	Ferredoxin
G3W92_RS01615	COG2945	thiolester hydrolase activity
G3W92_RS01620	COG1686	Belongs to the peptidase S11 family
G3W92_RS01625	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
G3W92_RS01630	COG0049	tRNA binding
G3W92_RS01635	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
G3W92_RS01640	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
G3W92_RS01645	COG0051	transcription antitermination factor activity, RNA binding
G3W92_RS01650	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
G3W92_RS01655	COG0088	Forms part of the polypeptide exit tunnel
G3W92_RS01660	COG0089	rRNA binding
G3W92_RS01665	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
G3W92_RS01670	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
G3W92_RS01675	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
G3W92_RS01680	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
G3W92_RS01685	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
G3W92_RS01690	COG0255	Belongs to the universal ribosomal protein uL29 family
G3W92_RS01695	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
G3W92_RS01700	COG0678	peroxiredoxin activity
G3W92_RS01720	COG3909	cytochrome
G3W92_RS01725	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G3W92_RS01740	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
G3W92_RS01745	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
G3W92_RS01750	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
G3W92_RS01755	COG0508	dehydrogenase complex catalyzes the overall conversion of
G3W92_RS01760	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G3W92_RS01765	COG0596	Alpha beta hydrolase
G3W92_RS01770	COG0280	phosphate acetyltransferase
G3W92_RS01770	COG0281	malic enzyme
G3W92_RS01775	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
G3W92_RS01780	COG1301	dicarboxylic acid transport
G3W92_RS01785	COG1252	NADH dehydrogenase
G3W92_RS01790	COG3243	poly(R)-hydroxyalkanoic acid synthase
G3W92_RS01795	COG0183	Belongs to the thiolase family
G3W92_RS01800	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS01805	COG1271	oxidase subunit
G3W92_RS01810	COG1294	oxidase, subunit
G3W92_RS01835	COG2205	protein histidine kinase activity
G3W92_RS01840	COG2130	NADP-dependent
G3W92_RS01850	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
G3W92_RS01855	COG0318	PFAM AMP-dependent synthetase and ligase
G3W92_RS01865	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
G3W92_RS01870	COG0321	lipoyl(octanoyl) transferase activity
G3W92_RS01875	COG2921	Belongs to the UPF0250 family
G3W92_RS01880	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
G3W92_RS01890	COG0356	it plays a direct role in the translocation of protons across the membrane
G3W92_RS01900	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
G3W92_RS01905	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
G3W92_RS01910	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
G3W92_RS01915	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
G3W92_RS01920	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
G3W92_RS01925	COG0355	proton-transporting ATP synthase activity, rotational mechanism
G3W92_RS01955	COG1129	ABC transporter
G3W92_RS01960	COG1172	Belongs to the binding-protein-dependent transport system permease family
G3W92_RS01965	COG1879	ABC-type sugar transport system periplasmic component
G3W92_RS01970	COG0673	inositol 2-dehydrogenase activity
G3W92_RS01975	COG0516	GMP reductase activity
G3W92_RS01975	COG0517	IMP dehydrogenase activity
G3W92_RS01985	COG1881	PFAM PEBP family protein
G3W92_RS01990	COG3588	fructose-bisphosphate aldolase
G3W92_RS01995	COG2902	Dehydrogenase
G3W92_RS02055	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G3W92_RS02060	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G3W92_RS02075	COG0583	DNA-binding transcription factor activity
G3W92_RS02080	COG4221	oxidoreductase activity
G3W92_RS02085	COG0583	DNA-binding transcription factor activity
G3W92_RS02105	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G3W92_RS02110	COG2226	methyltransferase
G3W92_RS02110	COG1073	alpha beta
G3W92_RS02115	COG0583	DNA-binding transcription factor activity
G3W92_RS02120	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS02145	COG0473	3-isopropylmalate dehydrogenase activity
G3W92_RS02155	COG0473	3-isopropylmalate dehydrogenase activity
G3W92_RS02160	COG0667	Aldo Keto reductase
G3W92_RS02190	COG2186	Transcriptional regulator
G3W92_RS02200	COG1012	belongs to the aldehyde dehydrogenase family
G3W92_RS02205	COG2084	Dehydrogenase
G3W92_RS02210	COG0667	Aldo Keto reductase
G3W92_RS02220	COG0667	Aldo Keto reductase
G3W92_RS02235	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
G3W92_RS02270	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W92_RS02310	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS02315	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS02325	COG3842	ATPase activity
G3W92_RS02330	COG0395	ABC-type sugar transport system, permease component
G3W92_RS02345	COG1233	COG1233 Phytoene dehydrogenase and related
G3W92_RS02350	COG1609	Transcriptional regulator
G3W92_RS02375	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
G3W92_RS02380	COG0792	nuclease activity
G3W92_RS02385	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
G3W92_RS02390	COG2823	Periplasmic or secreted lipoprotein
G3W92_RS02395	COG2084	Dehydrogenase
G3W92_RS02415	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
G3W92_RS02455	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
G3W92_RS02455	COG2124	cytochrome p450
G3W92_RS02460	COG1309	transcriptional regulator
G3W92_RS02465	COG0439	Biotin carboxylase
G3W92_RS02490	COG2376	Dihydroxyacetone kinase
G3W92_RS02510	COG1175	transmembrane transport
G3W92_RS02515	COG0395	ABC-type sugar transport system, permease component
G3W92_RS02520	COG3842	ATPase activity
G3W92_RS02525	COG0445	tRNA wobble uridine modification
G3W92_RS02530	COG1346	cytolysis
G3W92_RS02535	COG1380	Effector of murein hydrolase LrgA
G3W92_RS02540	COG0277	FAD linked oxidase domain protein
G3W92_RS02580	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G3W92_RS02630	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G3W92_RS02680	COG0343	queuine tRNA-ribosyltransferase activity
G3W92_RS02685	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
G3W92_RS02690	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
G3W92_RS02710	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
G3W92_RS02715	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
G3W92_RS02720	COG4770	biotin carboxylase activity
G3W92_RS02730	COG0783	Belongs to the Dps family
G3W92_RS02735	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
G3W92_RS02750	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
G3W92_RS02755	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
G3W92_RS02760	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
G3W92_RS02765	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
G3W92_RS02770	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
G3W92_RS02775	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
G3W92_RS02780	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
G3W92_RS02785	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
G3W92_RS02790	COG1841	ribosomal large subunit assembly
G3W92_RS02795	COG0200	Binds to the 23S rRNA
G3W92_RS02800	COG0201	protein transport
G3W92_RS02810	COG0257	Belongs to the bacterial ribosomal protein bL36 family
G3W92_RS02815	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
G3W92_RS02820	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
G3W92_RS02825	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
G3W92_RS02830	COG0202	RNA polymerase activity
G3W92_RS02835	COG0203	ribosomal protein L17
G3W92_RS02845	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
G3W92_RS02845	COG0506	proline dehydrogenase activity
G3W92_RS02845	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
G3W92_RS02865	COG1960	acyl-CoA dehydrogenase activity
G3W92_RS02870	COG1024	Enoyl-CoA hydratase
G3W92_RS02885	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G3W92_RS02905	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS02915	COG0022	dehydrogenase e1 component
G3W92_RS02920	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
G3W92_RS02935	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
G3W92_RS02940	COG2814	Major facilitator Superfamily
G3W92_RS02955	COG2814	Major facilitator Superfamily
G3W92_RS02965	COG1686	Belongs to the peptidase S11 family
G3W92_RS02995	COG1595	DNA-templated transcription, initiation
G3W92_RS03020	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W92_RS03035	COG0667	Aldo Keto reductase
G3W92_RS03040	COG0346	lactoylglutathione lyase activity
G3W92_RS03075	COG4213	ABC transporter substrate-binding protein
G3W92_RS03080	COG4214	carbohydrate transport
G3W92_RS03085	COG1129	ABC transporter
G3W92_RS03125	COG0477	Major facilitator Superfamily
G3W92_RS03160	COG1022	Amp-dependent synthetase and ligase
G3W92_RS03165	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G3W92_RS03175	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS03195	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
G3W92_RS03200	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
G3W92_RS03205	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
G3W92_RS03210	COG2205	protein histidine kinase activity
G3W92_RS03215	COG0745	RESPONSE REGULATOR receiver
G3W92_RS03220	COG1187	pseudouridine synthase activity
G3W92_RS03230	COG0745	RESPONSE REGULATOR receiver
G3W92_RS03235	COG0642	Histidine kinase
G3W92_RS03270	COG0326	Molecular chaperone. Has ATPase activity
G3W92_RS03275	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W92_RS03280	COG3181	Tripartite tricarboxylate transporter family receptor
G3W92_RS03285	COG1960	acyl-CoA dehydrogenase activity
G3W92_RS03290	COG0583	DNA-binding transcription factor activity
G3W92_RS03300	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
G3W92_RS03310	COG1012	belongs to the aldehyde dehydrogenase family
G3W92_RS03320	COG0318	PFAM AMP-dependent synthetase and ligase
G3W92_RS03325	COG2267	carboxylic ester hydrolase activity
G3W92_RS03340	COG0183	Belongs to the thiolase family
G3W92_RS03355	COG1764	response to oxidative stress
G3W92_RS03360	COG1846	Transcriptional regulator
G3W92_RS03370	COG1250	3-hydroxyacyl-CoA dehydrogenase
G3W92_RS03375	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
G3W92_RS03395	COG0724	RNA recognition motif
G3W92_RS03400	COG3530	Putative quorum-sensing-regulated virulence factor
G3W92_RS03405	COG0513	Belongs to the DEAD box helicase family
G3W92_RS03415	COG0842	Transport permease protein
G3W92_RS03420	COG1131	(ABC) transporter
G3W92_RS03425	COG0583	DNA-binding transcription factor activity
G3W92_RS03430	COG0625	glutathione transferase activity
G3W92_RS03440	COG2124	cytochrome p450
G3W92_RS03445	COG0640	Transcriptional regulator
G3W92_RS03450	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
G3W92_RS03470	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
G3W92_RS03475	COG4208	sulfate ABC transporter
G3W92_RS03485	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
G3W92_RS03510	COG1652	LysM domain
G3W92_RS03515	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
G3W92_RS03520	COG2733	membrane
G3W92_RS03525	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G3W92_RS03530	COG1473	amidohydrolase
G3W92_RS03545	COG0243	molybdopterin cofactor binding
G3W92_RS03560	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W92_RS03630	COG4106	trans-aconitate 2-methyltransferase activity
G3W92_RS03645	COG2076	Multidrug Resistance protein
G3W92_RS03655	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
G3W92_RS03660	COG1086	Polysaccharide biosynthesis protein
G3W92_RS03725	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
G3W92_RS03740	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
G3W92_RS03745	COG1216	Glycosyl transferase, family 2
G3W92_RS03755	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G3W92_RS03775	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
G3W92_RS03775	COG0662	Cupin 2, conserved barrel domain protein
G3W92_RS03780	COG1216	Glycosyl transferase, family 2
G3W92_RS03780	COG0438	transferase activity, transferring glycosyl groups
G3W92_RS03795	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
G3W92_RS03795	COG2755	lipolytic protein G-D-S-L family
G3W92_RS03805	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
G3W92_RS03810	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
G3W92_RS03820	COG0753	catalase activity
G3W92_RS03835	COG2119	membrane
G3W92_RS03845	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
G3W92_RS03860	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
G3W92_RS03880	COG0559	Belongs to the binding-protein-dependent transport system permease family
G3W92_RS03885	COG1137	ATPase activity
G3W92_RS03920	COG3064	Membrane
G3W92_RS03940	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
G3W92_RS03945	COG2721	sulfolactate sulfo-lyase activity
G3W92_RS03950	COG2186	Transcriptional regulator
G3W92_RS03955	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS03965	COG0765	amino acid transport
G3W92_RS03970	COG0765	amino acid transport
G3W92_RS03985	COG4948	Mandelate Racemase Muconate Lactonizing
G3W92_RS04005	COG2188	Transcriptional regulator
G3W92_RS04040	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
G3W92_RS04045	COG0066	3-isopropylmalate dehydratase activity
G3W92_RS04075	COG3976	FMN-binding domain protein
G3W92_RS04075	COG0431	NADPH-dependent FMN reductase
G3W92_RS04075	COG1053	succinate dehydrogenase
G3W92_RS04095	COG1960	acyl-CoA dehydrogenase activity
G3W92_RS04105	COG1250	3-hydroxyacyl-CoA dehydrogenase
G3W92_RS04105	COG1024	Enoyl-CoA hydratase
G3W92_RS04110	COG2852	Protein conserved in bacteria
G3W92_RS04115	COG0183	Belongs to the thiolase family
G3W92_RS04135	COG1024	Enoyl-CoA hydratase
G3W92_RS04140	COG1607	acyl-coa hydrolase
G3W92_RS04145	COG5265	(ABC) transporter
G3W92_RS04150	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G3W92_RS04155	COG0583	DNA-binding transcription factor activity
G3W92_RS04165	COG0765	amino acid transport
G3W92_RS04170	COG0765	amino acid transport
G3W92_RS04175	COG1126	abc transporter atp-binding protein
G3W92_RS04180	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G3W92_RS04195	COG1280	lysine exporter protein (LysE YggA)
G3W92_RS04205	COG2003	Belongs to the UPF0758 family
G3W92_RS04215	COG0418	dihydroorotase activity
G3W92_RS04225	COG0501	Belongs to the peptidase M48B family
G3W92_RS04230	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
G3W92_RS04265	COG1187	pseudouridine synthase activity
G3W92_RS04270	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G3W92_RS04280	COG1030	water channel activity
G3W92_RS04285	COG0330	HflC and HflK could
G3W92_RS04290	COG0598	Magnesium transport protein CorA
G3W92_RS04305	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G3W92_RS04315	COG2807	transmembrane transport
G3W92_RS04330	COG2175	clavaminate synthase activity
G3W92_RS04345	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G3W92_RS04360	COG2175	clavaminate synthase activity
G3W92_RS04405	COG0508	dehydrogenase complex catalyzes the overall conversion of
G3W92_RS04405	COG0596	Alpha beta hydrolase
G3W92_RS04415	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G3W92_RS04425	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3W92_RS04435	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
G3W92_RS04450	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
G3W92_RS04455	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
G3W92_RS04460	COG0523	cobalamin synthesis protein
G3W92_RS04475	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
G3W92_RS04480	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
G3W92_RS04485	COG2001	Belongs to the MraZ family
G3W92_RS04490	COG0275	rRNA processing
G3W92_RS04505	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
G3W92_RS04510	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
G3W92_RS04515	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
G3W92_RS04520	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
G3W92_RS04525	COG0772	Belongs to the SEDS family
G3W92_RS04530	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
G3W92_RS04535	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
G3W92_RS04540	COG1181	Belongs to the D-alanine--D-alanine ligase family
G3W92_RS04545	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
G3W92_RS04555	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
G3W92_RS04560	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
G3W92_RS04565	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
G3W92_RS04570	COG0575	Belongs to the CDS family
G3W92_RS04580	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G3W92_RS04585	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
G3W92_RS04600	COG3150	esterase
G3W92_RS04605	COG2197	response regulator
G3W92_RS04615	COG0772	Belongs to the SEDS family
G3W92_RS04620	COG0312	modulator of DNA gyrase
G3W92_RS04625	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
G3W92_RS04635	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
G3W92_RS04650	COG0511	ligase activity, forming carbon-carbon bonds
G3W92_RS04655	COG0439	Biotin carboxylase
G3W92_RS04660	COG2264	protein methyltransferase activity
G3W92_RS04670	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G3W92_RS04680	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G3W92_RS04715	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
G3W92_RS04720	COG2943	transferase activity, transferring hexosyl groups
G3W92_RS04720	COG3416	Protein conserved in bacteria
G3W92_RS04730	COG2204	response regulator
G3W92_RS04740	COG2205	protein histidine kinase activity
G3W92_RS04745	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
G3W92_RS04755	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G3W92_RS04760	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G3W92_RS04780	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G3W92_RS04795	COG0037	tRNA processing
G3W92_RS04805	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS04815	COG2175	clavaminate synthase activity
G3W92_RS04825	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
G3W92_RS04830	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3W92_RS04855	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
G3W92_RS04865	COG0617	tRNA 3'-terminal CCA addition
G3W92_RS04880	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
G3W92_RS04885	COG0583	DNA-binding transcription factor activity
G3W92_RS04895	COG2200	EAL domain
G3W92_RS04900	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G3W92_RS04915	COG0110	maltose O-acetyltransferase activity
G3W92_RS04920	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
G3W92_RS04925	COG1522	sequence-specific DNA binding
G3W92_RS04935	COG1254	Belongs to the acylphosphatase family
G3W92_RS04970	COG0318	PFAM AMP-dependent synthetase and ligase
G3W92_RS04975	COG0183	Belongs to the thiolase family
G3W92_RS04995	COG0515	serine threonine protein kinase
G3W92_RS04995	COG2815	serine threonine protein kinase
G3W92_RS05005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G3W92_RS05010	COG4597	amino acid ABC transporter
G3W92_RS05015	COG0765	amino acid transport
G3W92_RS05020	COG1126	abc transporter atp-binding protein
G3W92_RS05050	COG2072	flavoprotein involved in K transport
G3W92_RS05065	COG5002	protein histidine kinase activity
G3W92_RS05065	COG3447	MASE1 domain protein
G3W92_RS05065	COG5001	Diguanylate cyclase
G3W92_RS05075	COG0129	dihydroxy-acid dehydratase activity
G3W92_RS05090	COG3386	PFAM SMP-30 Gluconolaconase
G3W92_RS05100	COG1012	belongs to the aldehyde dehydrogenase family
G3W92_RS05105	COG1879	ABC-type sugar transport system periplasmic component
G3W92_RS05120	COG4214	carbohydrate transport
G3W92_RS05125	COG1129	ABC transporter
G3W92_RS05130	COG1172	Belongs to the binding-protein-dependent transport system permease family
G3W92_RS05135	COG1172	Belongs to the binding-protein-dependent transport system permease family
G3W92_RS05165	COG0189	ligase activity
G3W92_RS05165	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
G3W92_RS05170	COG0189	ligase activity
G3W92_RS05170	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
G3W92_RS05175	COG1132	(ABC) transporter
G3W92_RS05185	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
G3W92_RS05190	COG4178	(ABC) transporter
G3W92_RS05200	COG1459	type II secretion system
G3W92_RS05245	COG4970	Tfp pilus assembly protein FimT
G3W92_RS05260	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
G3W92_RS05265	COG1765	OsmC-like protein
G3W92_RS05270	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
G3W92_RS05285	COG1473	amidohydrolase
G3W92_RS05290	COG4166	transmembrane transport
G3W92_RS05295	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G3W92_RS05300	COG0444	Belongs to the ABC transporter superfamily
G3W92_RS05305	COG4608	Belongs to the ABC transporter superfamily
G3W92_RS05310	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
G3W92_RS05315	COG1840	ABC-type Fe3 transport system, periplasmic component
G3W92_RS05325	COG3842	ATPase activity
G3W92_RS05340	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
G3W92_RS05345	COG0166	Belongs to the GPI family
G3W92_RS05350	COG0439	Biotin carboxylase
G3W92_RS05355	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W92_RS05370	COG1802	Transcriptional regulator
G3W92_RS05385	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G3W92_RS05400	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
G3W92_RS05405	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
G3W92_RS05410	COG0745	RESPONSE REGULATOR receiver
G3W92_RS05415	COG5002	protein histidine kinase activity
G3W92_RS05420	COG0459	protein refolding
G3W92_RS05425	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
G3W92_RS05430	COG2186	Transcriptional regulator
G3W92_RS05435	COG2807	transmembrane transport
G3W92_RS05440	COG0456	acetyltransferase
G3W92_RS05460	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G3W92_RS05465	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W92_RS05475	COG0318	PFAM AMP-dependent synthetase and ligase
G3W92_RS05500	COG2207	Transcriptional regulator
G3W92_RS05510	COG0625	glutathione transferase activity
G3W92_RS05530	COG4772	TonB-dependent receptor
G3W92_RS05540	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
G3W92_RS05550	COG1560	Kdo2-lipid A biosynthetic process
G3W92_RS05560	COG0218	Necessary for normal cell division and for the maintenance of normal septation
G3W92_RS05570	COG1333	cytochrome c biogenesis protein
G3W92_RS05575	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
G3W92_RS05580	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
G3W92_RS05585	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
G3W92_RS05600	COG1965	Belongs to the frataxin family
G3W92_RS05635	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
G3W92_RS05645	COG0232	Belongs to the dGTPase family. Type 2 subfamily
G3W92_RS05670	COG0067	glutamate synthase
G3W92_RS05670	COG0069	glutamate synthase activity
G3W92_RS05670	COG0070	glutamate synthase
G3W92_RS05680	COG1127	ABC transporter
G3W92_RS05685	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G3W92_RS05690	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G3W92_RS05710	COG1131	(ABC) transporter
G3W92_RS05715	COG0842	Transport permease protein
G3W92_RS05720	COG5007	Belongs to the BolA IbaG family
G3W92_RS05725	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
G3W92_RS05730	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
G3W92_RS05735	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
G3W92_RS05745	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
G3W92_RS05750	COG0131	Imidazoleglycerol-phosphate dehydratase
G3W92_RS05760	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
G3W92_RS05770	COG1301	dicarboxylic acid transport
G3W92_RS05780	COG0107	imidazoleglycerol-phosphate synthase activity
G3W92_RS05785	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
G3W92_RS05790	COG0140	phosphoribosyl-ATP diphosphatase activity
G3W92_RS05800	COG0537	adenosine 5'-monophosphoramidase activity
G3W92_RS05805	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G3W92_RS05810	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G3W92_RS05815	COG0805	protein transport
G3W92_RS05820	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G3W92_RS05825	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
G3W92_RS05830	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
G3W92_RS05835	COG1970	mechanosensitive ion channel activity
G3W92_RS05840	COG0723	plastoquinol--plastocyanin reductase activity
G3W92_RS05845	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
G3W92_RS05850	COG2857	Cytochrome c1
G3W92_RS05855	COG0625	glutathione transferase activity
G3W92_RS05860	COG2969	positive regulation of protein catabolic process
G3W92_RS05870	COG3181	Tripartite tricarboxylate transporter family receptor
G3W92_RS05880	COG1309	transcriptional regulator
G3W92_RS05895	COG0653	protein targeting
G3W92_RS05900	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
G3W92_RS05915	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
G3W92_RS05920	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
G3W92_RS05930	COG1696	Membrane protein involved in D-alanine export
G3W92_RS05960	COG0142	geranyltranstransferase activity
G3W92_RS05965	COG0261	This protein binds to 23S rRNA in the presence of protein L20
G3W92_RS05970	COG0211	Belongs to the bacterial ribosomal protein bL27 family
G3W92_RS05975	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
G3W92_RS05980	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
G3W92_RS05990	COG0494	nUDIX hydrolase
G3W92_RS05995	COG0442	prolyl-tRNA aminoacylation
G3W92_RS06000	COG0741	lytic transglycosylase activity
G3W92_RS06005	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
G3W92_RS06015	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
G3W92_RS06020	COG2890	protein-(glutamine-N5) methyltransferase activity
G3W92_RS06025	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
G3W92_RS06030	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
G3W92_RS06040	COG3264	Mechanosensitive ion channel
G3W92_RS06040	COG1511	domain protein
G3W92_RS06045	COG0584	glycerophosphoryl diester phosphodiesterase
G3W92_RS06050	COG3842	ATPase activity
G3W92_RS06055	COG0395	ABC-type sugar transport system, permease component
G3W92_RS06060	COG1175	transmembrane transport
G3W92_RS06070	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G3W92_RS06090	COG2226	methyltransferase
G3W92_RS06105	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
G3W92_RS06110	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
G3W92_RS06115	COG3842	ATPase activity
G3W92_RS06120	COG1176	ABC-type spermidine putrescine transport system, permease component I
G3W92_RS06125	COG1177	transmembrane transport
G3W92_RS06140	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
G3W92_RS06150	COG3181	Tripartite tricarboxylate transporter family receptor
G3W92_RS06165	COG3568	Endonuclease Exonuclease Phosphatase
G3W92_RS06170	COG0302	gtp cyclohydrolase
G3W92_RS06180	COG2076	Multidrug Resistance protein
G3W92_RS06220	COG4585	Histidine kinase
G3W92_RS06225	COG2197	response regulator
G3W92_RS06235	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
G3W92_RS06240	COG0793	Belongs to the peptidase S41A family
G3W92_RS06245	COG0588	phosphoglycerate mutase activity
G3W92_RS06250	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G3W92_RS06260	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
G3W92_RS06265	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
G3W92_RS06275	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
G3W92_RS06285	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
G3W92_RS06290	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
G3W92_RS06295	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
G3W92_RS06300	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
G3W92_RS06330	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G3W92_RS06330	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G3W92_RS06335	COG3132	Protein of unknown function, DUF480
G3W92_RS06350	COG0489	protein tyrosine kinase activity
G3W92_RS06355	COG2223	nitrite transmembrane transporter activity
G3W92_RS06365	COG3383	formate dehydrogenase (NAD+) activity
G3W92_RS06385	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
G3W92_RS06390	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
G3W92_RS06395	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G3W92_RS06410	COG2003	Belongs to the UPF0758 family
G3W92_RS06415	COG1047	Peptidyl-prolyl cis-trans
G3W92_RS06420	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
G3W92_RS06435	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
G3W92_RS06455	COG0242	peptide deformylase activity
G3W92_RS06470	COG4638	Rieske (2fe-2S)
G3W92_RS06490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G3W92_RS06510	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
G3W92_RS06560	COG0318	PFAM AMP-dependent synthetase and ligase
G3W92_RS06595	COG1063	alcohol dehydrogenase
G3W92_RS06605	COG3328	transposase activity
G3W92_RS06625	COG1960	acyl-CoA dehydrogenase activity
G3W92_RS06680	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS06685	COG3246	L-lysine catabolic process to acetate
G3W92_RS06695	COG1176	ABC-type spermidine putrescine transport system, permease component I
G3W92_RS06700	COG1177	transmembrane transport
G3W92_RS06740	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G3W92_RS06745	COG2175	clavaminate synthase activity
G3W92_RS06775	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G3W92_RS06775	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G3W92_RS06780	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G3W92_RS06780	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G3W92_RS06785	COG1024	Enoyl-CoA hydratase
G3W92_RS06805	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
G3W92_RS06840	COG3128	pkhd-type hydroxylase
G3W92_RS06845	COG4774	siderophore transport
G3W92_RS06850	COG5002	protein histidine kinase activity
G3W92_RS06855	COG2197	response regulator
G3W92_RS06860	COG0180	Tryptophanyl-tRNA synthetase
G3W92_RS06865	COG1994	Peptidase M50
G3W92_RS06870	COG0009	L-threonylcarbamoyladenylate synthase
G3W92_RS06880	COG0613	PHP domain protein
G3W92_RS06890	COG0306	phosphate transporter
G3W92_RS06925	COG1129	ABC transporter
G3W92_RS06935	COG3540	Alkaline phosphatase
G3W92_RS06955	COG0477	Major facilitator Superfamily
G3W92_RS06960	COG0829	nickel cation binding
G3W92_RS07000	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
G3W92_RS07070	COG0163	prenyltransferase activity
G3W92_RS07075	COG0523	cobalamin synthesis protein
G3W92_RS07080	COG1529	Aldehyde oxidase and xanthine dehydrogenase
G3W92_RS07080	COG2080	2 iron, 2 sulfur cluster binding
G3W92_RS07095	COG0583	DNA-binding transcription factor activity
G3W92_RS07100	COG2233	PERMEase
G3W92_RS07105	COG0281	malic enzyme
G3W92_RS07105	COG0280	phosphate acetyltransferase
G3W92_RS07110	COG2084	Dehydrogenase
G3W92_RS07115	COG3622	Belongs to the hyi family
G3W92_RS07120	COG3960	tartronate-semialdehyde synthase activity
G3W92_RS07125	COG0583	DNA-binding transcription factor activity
G3W92_RS07140	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G3W92_RS07145	COG3181	Tripartite tricarboxylate transporter family receptor
G3W92_RS07150	COG0251	oxidation-reduction process
G3W92_RS07160	COG0179	Fumarylacetoacetate (FAA) hydrolase
G3W92_RS07165	COG3971	2-oxopent-4-enoate hydratase activity
G3W92_RS07175	COG3548	integral membrane protein
G3W92_RS07195	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G3W92_RS07200	COG0439	Biotin carboxylase
G3W92_RS07215	COG0559	Belongs to the binding-protein-dependent transport system permease family
G3W92_RS07235	COG0318	PFAM AMP-dependent synthetase and ligase
G3W92_RS07295	COG0583	DNA-binding transcription factor activity
G3W92_RS07320	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G3W92_RS07325	COG2801	Transposase and inactivated derivatives
G3W92_RS07360	COG0628	permease
G3W92_RS07365	COG2186	Transcriptional regulator
G3W92_RS07370	COG1301	dicarboxylic acid transport
G3W92_RS07375	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
G3W92_RS07400	COG0656	L-ascorbic acid biosynthetic process
G3W92_RS07405	COG1953	Uracil, thiamine, allantoin
G3W92_RS07410	COG2233	PERMEase
G3W92_RS07425	COG1953	Uracil, thiamine, allantoin
G3W92_RS07445	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G3W92_RS07460	COG2186	Transcriptional regulator
G3W92_RS07525	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G3W92_RS07540	COG2133	pyrroloquinoline quinone binding
G3W92_RS07550	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
G3W92_RS07555	COG1021	2,3-dihydroxybenzoate-AMP ligase
G3W92_RS07590	COG1320	monovalent cation:proton antiporter activity
G3W92_RS07595	COG2212	antiporter activity
G3W92_RS07605	COG0651	ATP synthesis coupled electron transport
G3W92_RS07610	COG1006	Multisubunit Na H antiporter MnhC subunit
G3W92_RS07615	COG2111	Na H antiporter
G3W92_RS07615	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
G3W92_RS07620	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
G3W92_RS07630	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
G3W92_RS07650	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
G3W92_RS07655	COG0287	Prephenate dehydrogenase
G3W92_RS07665	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
G3W92_RS07685	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G3W92_RS07715	COG4797	methyltransferase
G3W92_RS07715	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G3W92_RS07725	COG1187	pseudouridine synthase activity
G3W92_RS07750	COG1058	Belongs to the CinA family
G3W92_RS07750	COG1546	Belongs to the CinA family
G3W92_RS07755	COG0174	glutamine synthetase
G3W92_RS07765	COG3852	Histidine kinase
G3W92_RS07770	COG2204	response regulator
G3W92_RS07780	COG0708	Exodeoxyribonuclease III
G3W92_RS07785	COG1956	GAF domain-containing protein
G3W92_RS07815	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G3W92_RS07845	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
G3W92_RS07855	COG0277	FAD linked oxidase domain protein
G3W92_RS07865	COG1295	ribonuclease BN
G3W92_RS07870	COG3118	belongs to the thioredoxin family
G3W92_RS07915	COG1538	Outer membrane efflux protein
G3W92_RS07930	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G3W92_RS07935	COG3181	Tripartite tricarboxylate transporter family receptor
G3W92_RS07950	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
G3W92_RS07955	COG0596	Alpha beta hydrolase
G3W92_RS07965	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
G3W92_RS07970	COG2818	Glycosylase
G3W92_RS07975	COG2719	SpoVR family
G3W92_RS07980	COG2718	Belongs to the UPF0229 family
G3W92_RS07985	COG2766	serine protein kinase
G3W92_RS07995	COG0179	Fumarylacetoacetate (FAA) hydrolase
G3W92_RS08000	COG2186	Transcriptional regulator
G3W92_RS08025	COG0673	inositol 2-dehydrogenase activity
G3W92_RS08040	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G3W92_RS08085	COG0484	heat shock protein binding
G3W92_RS08090	COG0443	Heat shock 70 kDa protein
G3W92_RS08095	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
G3W92_RS08115	COG0688	phosphatidylethanolamine metabolic process
G3W92_RS08125	COG2721	sulfolactate sulfo-lyase activity
G3W92_RS08130	COG2706	6-phosphogluconolactonase activity
G3W92_RS08145	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G3W92_RS08150	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G3W92_RS08155	COG2186	Transcriptional regulator
G3W92_RS08165	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G3W92_RS08170	COG1012	belongs to the aldehyde dehydrogenase family
G3W92_RS08195	COG2188	Transcriptional regulator
G3W92_RS08200	COG0683	leucine binding
G3W92_RS08215	COG0559	Belongs to the binding-protein-dependent transport system permease family
G3W92_RS08225	COG1129	ABC transporter
G3W92_RS08250	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G3W92_RS08260	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
G3W92_RS08285	COG1137	ATPase activity
G3W92_RS08315	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
G3W92_RS08335	COG1125	glycine betaine transport
G3W92_RS08335	COG0517	IMP dehydrogenase activity
G3W92_RS08340	COG2814	Major facilitator Superfamily
G3W92_RS08350	COG0358	DNA primase activity
G3W92_RS08355	COG1295	ribonuclease BN
G3W92_RS08380	COG3237	CsbD-like
G3W92_RS08385	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
G3W92_RS08410	COG1611	Belongs to the LOG family
G3W92_RS08415	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
G3W92_RS08425	COG0322	excinuclease ABC activity
G3W92_RS08440	COG0473	3-isopropylmalate dehydrogenase activity
G3W92_RS08455	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G3W92_RS08475	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
G3W92_RS08480	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
G3W92_RS08495	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
G3W92_RS08500	COG0670	Belongs to the BI1 family
G3W92_RS08505	COG3193	protein, possibly involved in utilization of glycolate and propanediol
G3W92_RS08535	COG3128	pkhd-type hydroxylase
G3W92_RS08540	COG4774	siderophore transport
G3W92_RS08545	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
G3W92_RS08550	COG1477	protein flavinylation
G3W92_RS08580	COG3634	alkyl hydroperoxide reductase activity
G3W92_RS08595	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
G3W92_RS08610	COG0360	Binds together with S18 to 16S ribosomal RNA
G3W92_RS08615	COG2965	DNA replication, synthesis of RNA primer
G3W92_RS08620	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
G3W92_RS08625	COG0359	binds to the 23S rRNA
G3W92_RS08650	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
G3W92_RS08655	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
G3W92_RS08665	COG0436	Aminotransferase
G3W92_RS08680	COG1763	Mo-molybdopterin cofactor biosynthetic process
G3W92_RS08685	COG0303	'Molybdopterin
G3W92_RS08690	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
G3W92_RS08695	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G3W92_RS08700	COG0314	molybdopterin synthase activity
G3W92_RS08705	COG0583	DNA-binding transcription factor activity
G3W92_RS08725	COG0542	response to heat
G3W92_RS08765	COG0431	NADPH-dependent FMN reductase
G3W92_RS08805	COG3214	Protein conserved in bacteria
G3W92_RS08815	COG2084	Dehydrogenase
G3W92_RS08835	COG0673	inositol 2-dehydrogenase activity
G3W92_RS08860	COG3181	Tripartite tricarboxylate transporter family receptor
G3W92_RS08865	COG1309	transcriptional regulator
G3W92_RS08870	COG0028	Belongs to the TPP enzyme family
G3W92_RS08885	COG2224	Isocitrate lyase
G3W92_RS08890	COG2246	polysaccharide biosynthetic process
G3W92_RS08895	COG0546	phosphoglycolate phosphatase activity
G3W92_RS08895	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
G3W92_RS08905	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
G3W92_RS08910	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
G3W92_RS08915	COG0291	Belongs to the bacterial ribosomal protein bL35 family
G3W92_RS08920	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
G3W92_RS08925	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
G3W92_RS08930	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G3W92_RS08930	COG0072	phenylalanine-tRNA ligase activity
G3W92_RS08935	COG0776	regulation of translation
G3W92_RS09010	COG0740	serine-type endopeptidase activity
G3W92_RS09040	COG0025	NhaP-type Na H and K H
G3W92_RS09045	COG0667	Aldo Keto reductase
G3W92_RS09055	COG0583	DNA-binding transcription factor activity
G3W92_RS09070	COG2301	Belongs to the HpcH HpaI aldolase family
G3W92_RS09075	COG1960	acyl-CoA dehydrogenase activity
G3W92_RS09080	COG1024	Enoyl-CoA hydratase
G3W92_RS09085	COG0427	acetyl-CoA hydrolase
G3W92_RS09100	COG0583	DNA-binding transcription factor activity
G3W92_RS09105	COG1968	undecaprenyl-diphosphatase activity
G3W92_RS09130	COG1132	(ABC) transporter
G3W92_RS09135	COG3045	CreA protein
G3W92_RS09165	COG3243	poly(R)-hydroxyalkanoic acid synthase
G3W92_RS09170	COG0183	Belongs to the thiolase family
G3W92_RS09175	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G3W92_RS09180	COG0477	Major facilitator Superfamily
G3W92_RS09185	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS09190	COG1301	dicarboxylic acid transport
G3W92_RS09195	COG4651	solute:proton antiporter activity
G3W92_RS09195	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
G3W92_RS09210	COG1070	Carbohydrate kinase
G3W92_RS09215	COG2207	Transcriptional regulator
G3W92_RS09215	COG4753	response regulator
G3W92_RS09225	COG0246	Mannitol dehydrogenase
G3W92_RS09235	COG0395	ABC-type sugar transport system, permease component
G3W92_RS09240	COG1175	transmembrane transport
G3W92_RS09370	COG1012	belongs to the aldehyde dehydrogenase family
G3W92_RS09385	COG0477	Major facilitator Superfamily
G3W92_RS09395	COG2169	Transcriptional regulator
G3W92_RS09395	COG1917	Cupin 2, conserved barrel domain protein
G3W92_RS09400	COG3976	FMN-binding domain protein
G3W92_RS09400	COG1053	succinate dehydrogenase
G3W92_RS09405	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
G3W92_RS09415	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G3W92_RS09425	COG1126	abc transporter atp-binding protein
G3W92_RS09430	COG0765	amino acid transport
G3W92_RS09440	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS09445	COG1802	Transcriptional regulator
G3W92_RS09450	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G3W92_RS09450	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G3W92_RS09455	COG1703	isobutyryl-CoA mutase activity
G3W92_RS09460	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G3W92_RS09465	COG4770	biotin carboxylase activity
G3W92_RS09480	COG2878	Part of a membrane complex involved in electron transport
G3W92_RS09495	COG0556	nucleotide-excision repair
G3W92_RS09500	COG1959	2 iron, 2 sulfur cluster binding
G3W92_RS09505	COG1104	cysteine desulfurase activity
G3W92_RS09510	COG0822	iron-sulfur transferase activity
G3W92_RS09520	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
G3W92_RS09525	COG0443	Heat shock 70 kDa protein
G3W92_RS09535	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
G3W92_RS09560	COG0167	dihydroorotate dehydrogenase activity
G3W92_RS09565	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
G3W92_RS09580	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
G3W92_RS09585	COG4566	intracellular signal transduction
G3W92_RS09590	COG4191	Histidine kinase
G3W92_RS09595	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
G3W92_RS09600	COG0508	dehydrogenase complex catalyzes the overall conversion of
G3W92_RS09605	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
G3W92_RS09610	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G3W92_RS09615	COG0791	NLP P60 protein
G3W92_RS09630	COG2368	4-hydroxyphenylacetate
G3W92_RS09655	COG0567	Dehydrogenase, E1 component
G3W92_RS09660	COG0508	dehydrogenase complex catalyzes the overall conversion of
G3W92_RS09665	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G3W92_RS09670	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
G3W92_RS09685	COG1199	ATP-dependent helicase activity
G3W92_RS09695	COG0564	pseudouridine synthase activity
G3W92_RS09705	COG1187	pseudouridine synthase activity
G3W92_RS09710	COG0105	UTP biosynthetic process
G3W92_RS09715	COG0820	rRNA (adenine-C2-)-methyltransferase activity
G3W92_RS09730	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
G3W92_RS09735	COG0124	histidyl-tRNA synthetase
G3W92_RS09745	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G3W92_RS09750	COG1160	GTP binding
G3W92_RS09755	COG1923	regulation of RNA biosynthetic process
G3W92_RS09760	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
G3W92_RS09765	COG0330	HflC and HflK could
G3W92_RS09770	COG0330	HflC and HflK could
G3W92_RS09775	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
G3W92_RS09780	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
G3W92_RS09785	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
G3W92_RS09795	COG0626	cystathionine gamma-synthase activity
G3W92_RS09810	COG1136	(ABC) transporter
G3W92_RS09815	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G3W92_RS09825	COG3618	amidohydrolase
G3W92_RS09830	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS09860	COG0667	Aldo Keto reductase
G3W92_RS09875	COG1295	ribonuclease BN
G3W92_RS09880	COG3119	arylsulfatase activity
G3W92_RS09890	COG0583	DNA-binding transcription factor activity
G3W92_RS09910	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
G3W92_RS09930	COG2951	lytic endotransglycosylase activity
G3W92_RS09945	COG0714	Associated with various cellular activities
G3W92_RS09955	COG3264	Mechanosensitive ion channel
G3W92_RS09955	COG1196	nuclear chromosome segregation
G3W92_RS09970	COG1960	acyl-CoA dehydrogenase activity
G3W92_RS10000	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
G3W92_RS10025	COG1414	Transcriptional regulator
G3W92_RS10030	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
G3W92_RS10040	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
G3W92_RS10050	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G3W92_RS10055	COG2814	Major facilitator Superfamily
G3W92_RS10085	COG0583	DNA-binding transcription factor activity
G3W92_RS10100	COG1116	anion transmembrane transporter activity
G3W92_RS10115	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
G3W92_RS10145	COG3384	dioxygenase
G3W92_RS10165	COG3384	dioxygenase
G3W92_RS10180	COG4941	Belongs to the sigma-70 factor family
G3W92_RS10185	COG3795	YCII-related domain
G3W92_RS10230	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
G3W92_RS10230	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
G3W92_RS10235	COG0509	glycine decarboxylation via glycine cleavage system
G3W92_RS10240	COG0404	The glycine cleavage system catalyzes the degradation of glycine
G3W92_RS10255	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS10270	COG0642	Histidine kinase
G3W92_RS10275	COG0745	RESPONSE REGULATOR receiver
G3W92_RS10285	COG2194	sulfuric ester hydrolase activity
G3W92_RS10310	COG4302	ethanolamine ammonia-lyase activity
G3W92_RS10315	COG4303	Ethanolamine ammonia lyase large subunit
G3W92_RS10335	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
G3W92_RS10340	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
G3W92_RS10340	COG2169	Transcriptional regulator
G3W92_RS10375	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W92_RS10405	COG1024	Enoyl-CoA hydratase
G3W92_RS10415	COG0583	DNA-binding transcription factor activity
G3W92_RS10420	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
G3W92_RS10430	COG1396	sequence-specific DNA binding
G3W92_RS10430	COG3800	Transcriptional regulator
G3W92_RS10445	COG3181	Tripartite tricarboxylate transporter family receptor
G3W92_RS10470	COG2366	antibiotic biosynthetic process
G3W92_RS10475	COG1183	phosphatidylcholine synthase activity
G3W92_RS10480	COG0519	Catalyzes the synthesis of GMP from XMP
G3W92_RS10485	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
G3W92_RS10495	COG1132	(ABC) transporter
G3W92_RS10500	COG3384	dioxygenase
G3W92_RS10545	COG0587	DNA-directed DNA polymerase activity
G3W92_RS10555	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
G3W92_RS10560	COG4608	Belongs to the ABC transporter superfamily
G3W92_RS10565	COG0444	Belongs to the ABC transporter superfamily
G3W92_RS10570	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G3W92_RS10575	COG0601	transmembrane transport
G3W92_RS10580	COG0747	negative chemotaxis
G3W92_RS10620	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G3W92_RS10625	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS10640	COG0589	response to stress
G3W92_RS10645	COG2217	Heavy metal translocating P-type atpase
G3W92_RS10655	COG3278	Belongs to the heme-copper respiratory oxidase family
G3W92_RS10690	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G3W92_RS10695	COG0635	Involved in the biosynthesis of porphyrin-containing compound
G3W92_RS10710	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G3W92_RS10735	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
G3W92_RS10745	COG4191	Histidine kinase
G3W92_RS10745	COG0784	Response regulator, receiver
G3W92_RS10780	COG0589	response to stress
G3W92_RS10785	COG0589	response to stress
G3W92_RS10795	COG0589	response to stress
G3W92_RS10815	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G3W92_RS10825	COG1914	H( )-stimulated, divalent metal cation uptake system
G3W92_RS10830	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
G3W92_RS10835	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
G3W92_RS10840	COG3328	transposase activity
G3W92_RS10860	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G3W92_RS10865	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G3W92_RS10880	COG3038	cytochrome b561
G3W92_RS10970	COG2204	response regulator
G3W92_RS10980	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
G3W92_RS11000	COG2267	carboxylic ester hydrolase activity
G3W92_RS11015	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G3W92_RS11045	COG1414	Transcriptional regulator
G3W92_RS11050	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS11055	COG0028	Belongs to the TPP enzyme family
G3W92_RS11060	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
G3W92_RS11065	COG1012	belongs to the aldehyde dehydrogenase family
G3W92_RS11100	COG2271	Major facilitator Superfamily
G3W92_RS11120	COG0220	tRNA (guanine-N7-)-methyltransferase activity
G3W92_RS11125	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G3W92_RS11130	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
G3W92_RS11130	COG0493	'glutamate synthase
G3W92_RS11140	COG1741	Belongs to the pirin family
G3W92_RS11145	COG2259	Doxx family
G3W92_RS11155	COG1741	Belongs to the pirin family
G3W92_RS11175	COG0848	biopolymer transport protein
G3W92_RS11185	COG0824	Thioesterase
G3W92_RS11190	COG0436	Aminotransferase
G3W92_RS11195	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
G3W92_RS11200	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
G3W92_RS11215	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G3W92_RS11215	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G3W92_RS11250	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
G3W92_RS11255	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
G3W92_RS11260	COG0741	lytic transglycosylase activity
G3W92_RS11275	COG3228	Belongs to the MtfA family
G3W92_RS11280	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G3W92_RS11300	COG0215	cysteine-tRNA ligase activity
G3W92_RS11310	COG0825	malonyl-CoA metabolic process
G3W92_RS11315	COG0037	tRNA processing
G3W92_RS11330	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
G3W92_RS11330	COG2755	lipolytic protein G-D-S-L family
G3W92_RS11335	COG1609	Transcriptional regulator
G3W92_RS11340	COG1063	alcohol dehydrogenase
G3W92_RS11345	COG1070	Carbohydrate kinase
G3W92_RS11360	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G3W92_RS11360	COG1116	anion transmembrane transporter activity
G3W92_RS11365	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3W92_RS11385	COG1525	nuclease
G3W92_RS11390	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
G3W92_RS11395	COG1250	3-hydroxyacyl-CoA dehydrogenase
G3W92_RS11395	COG1024	Enoyl-CoA hydratase
G3W92_RS11400	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G3W92_RS11405	COG0604	alcohol dehydrogenase
G3W92_RS11405	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS11405	COG3321	synthase
G3W92_RS11435	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G3W92_RS11440	COG4638	Rieske (2fe-2S)
G3W92_RS11465	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
G3W92_RS11505	COG0411	ABC transporter
G3W92_RS11515	COG0318	PFAM AMP-dependent synthetase and ligase
G3W92_RS11520	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS11545	COG2326	polyphosphate kinase activity
G3W92_RS11555	COG0642	Histidine kinase
G3W92_RS11565	COG3181	Tripartite tricarboxylate transporter family receptor
G3W92_RS11595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G3W92_RS11605	COG2204	response regulator
G3W92_RS11620	COG1126	abc transporter atp-binding protein
G3W92_RS11645	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
G3W92_RS11650	COG1011	Hydrolase
G3W92_RS11660	COG2124	cytochrome p450
G3W92_RS11675	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS11720	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS11725	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS11745	COG2124	cytochrome p450
G3W92_RS11755	COG0559	Belongs to the binding-protein-dependent transport system permease family
G3W92_RS11800	COG0655	NAD(P)H dehydrogenase (quinone) activity
G3W92_RS11820	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS11830	COG2814	Major facilitator Superfamily
G3W92_RS11840	COG0318	PFAM AMP-dependent synthetase and ligase
G3W92_RS11870	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
G3W92_RS11890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G3W92_RS11895	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G3W92_RS11905	COG0544	peptidyl-prolyl cis-trans isomerase activity
G3W92_RS11910	COG0740	serine-type endopeptidase activity
G3W92_RS11915	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
G3W92_RS11920	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
G3W92_RS11955	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
G3W92_RS11970	COG0114	fumarate hydratase activity
G3W92_RS11980	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G3W92_RS11990	COG4654	Cytochrome c, class I
G3W92_RS12000	COG0129	dihydroxy-acid dehydratase activity
G3W92_RS12005	COG0583	DNA-binding transcription factor activity
G3W92_RS12010	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
G3W92_RS12020	COG0318	PFAM AMP-dependent synthetase and ligase
G3W92_RS12045	COG4206	TonB-dependent receptor
G3W92_RS12050	COG1797	cobyrinic acid a,c-diamide synthase activity
G3W92_RS12060	COG4607	ABC-type enterochelin transport system periplasmic component
G3W92_RS12070	COG1121	(ABC) transporter
G3W92_RS12075	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
G3W92_RS12080	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
G3W92_RS12110	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G3W92_RS12120	COG1538	Outer membrane efflux protein
G3W92_RS12130	COG1492	cobalamin metabolic process
G3W92_RS12135	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
G3W92_RS12140	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
G3W92_RS12150	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
G3W92_RS12155	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G3W92_RS12165	COG0626	cystathionine gamma-synthase activity
G3W92_RS12170	COG0560	Phosphoserine phosphatase
G3W92_RS12175	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
G3W92_RS12180	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
G3W92_RS12180	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
G3W92_RS12185	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
G3W92_RS12185	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
G3W92_RS12190	COG2205	protein histidine kinase activity
G3W92_RS12195	COG0745	RESPONSE REGULATOR receiver
G3W92_RS12210	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G3W92_RS12230	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
G3W92_RS12235	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
G3W92_RS12245	COG0557	exoribonuclease II activity
G3W92_RS12250	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS12270	COG0052	Belongs to the universal ribosomal protein uS2 family
G3W92_RS12275	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
G3W92_RS12280	COG0528	UMP kinase activity
G3W92_RS12285	COG0233	cytoplasmic translational termination
G3W92_RS12295	COG0575	Belongs to the CDS family
G3W92_RS12300	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
G3W92_RS12305	COG0750	zinc metalloprotease
G3W92_RS12320	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G3W92_RS12325	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
G3W92_RS12330	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G3W92_RS12335	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G3W92_RS12340	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
G3W92_RS12345	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G3W92_RS12350	COG0505	Belongs to the CarA family
G3W92_RS12355	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
G3W92_RS12365	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G3W92_RS12380	COG1534	Rna-binding protein
G3W92_RS12385	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
G3W92_RS12390	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G3W92_RS12400	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G3W92_RS12425	COG1024	Enoyl-CoA hydratase
G3W92_RS12430	COG1250	3-hydroxyacyl-CoA dehydrogenase
G3W92_RS12440	COG2814	Major facilitator Superfamily
G3W92_RS12445	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G3W92_RS12455	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
G3W92_RS12460	COG0252	asparaginase activity
G3W92_RS12465	COG0563	adenylate kinase activity
G3W92_RS12470	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
G3W92_RS12475	COG2835	tetraacyldisaccharide 4'-kinase activity
G3W92_RS12480	COG1663	tetraacyldisaccharide 4'-kinase activity
G3W92_RS12485	COG0848	biopolymer transport protein
G3W92_RS12490	COG0811	peptide transport
G3W92_RS12495	COG1570	exodeoxyribonuclease VII activity
G3W92_RS12500	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
G3W92_RS12520	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
G3W92_RS12525	COG0542	response to heat
G3W92_RS12530	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G3W92_RS12535	COG2925	Exonuclease
G3W92_RS12550	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
G3W92_RS12550	COG0456	acetyltransferase
G3W92_RS12565	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G3W92_RS12575	COG5002	protein histidine kinase activity
G3W92_RS12590	COG3038	cytochrome b561
G3W92_RS12630	COG4774	siderophore transport
G3W92_RS12640	COG4585	Histidine kinase
G3W92_RS12645	COG0402	S-adenosylhomocysteine deaminase activity
G3W92_RS12650	COG0583	DNA-binding transcription factor activity
G3W92_RS12660	COG1024	Enoyl-CoA hydratase
G3W92_RS12675	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3W92_RS12690	COG3300	MHYT domain
G3W92_RS12690	COG5001	Diguanylate cyclase
G3W92_RS12695	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
G3W92_RS12710	COG0433	COG0433 Predicted ATPase
G3W92_RS12725	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
G3W92_RS12785	COG0217	transcriptional regulatory protein
G3W92_RS12790	COG0151	Belongs to the GarS family
G3W92_RS12795	COG0408	coproporphyrinogen oxidase activity
G3W92_RS12800	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
G3W92_RS12805	COG0799	negative regulation of ribosome biogenesis
G3W92_RS12810	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
G3W92_RS12815	COG0424	maF-like protein
G3W92_RS12820	COG1530	ribonuclease E activity
G3W92_RS12825	COG1132	(ABC) transporter
G3W92_RS12830	COG0823	Involved in the tonB-independent uptake of proteins
G3W92_RS12835	COG2885	chlorophyll binding
G3W92_RS12845	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
G3W92_RS12995	COG0071	Belongs to the small heat shock protein (HSP20) family
G3W92_RS13015	COG0582	viral genome integration into host DNA
G3W92_RS13030	COG0583	DNA-binding transcription factor activity
G3W92_RS13055	COG2890	protein-(glutamine-N5) methyltransferase activity
G3W92_RS13060	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G3W92_RS13070	COG2171	N-acyltransferase activity
G3W92_RS13075	COG0436	Aminotransferase
G3W92_RS13080	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
G3W92_RS13080	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
G3W92_RS13085	COG1643	Atp-dependent helicase
G3W92_RS13100	COG0436	Aminotransferase
G3W92_RS13105	COG0583	DNA-binding transcription factor activity
G3W92_RS13120	COG0795	lipopolysaccharide-transporting ATPase activity
G3W92_RS13125	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
G3W92_RS13175	COG1982	Orn Lys Arg decarboxylase major
G3W92_RS13180	COG1793	dna ligase
G3W92_RS13185	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
G3W92_RS13190	COG4166	transmembrane transport
G3W92_RS13195	COG4174	ABC transporter (Permease)
G3W92_RS13200	COG4239	(ABC) transporter, permease
G3W92_RS13205	COG4172	Belongs to the ABC transporter superfamily
G3W92_RS13210	COG0477	Major facilitator Superfamily
G3W92_RS13215	COG0779	Required for maturation of 30S ribosomal subunits
G3W92_RS13220	COG0195	Participates in both transcription termination and antitermination
G3W92_RS13220	COG2251	uridine kinase activity
G3W92_RS13225	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
G3W92_RS13230	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
G3W92_RS13235	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
G3W92_RS13270	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
G3W92_RS13275	COG2867	negative regulation of translational initiation
G3W92_RS13295	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G3W92_RS13295	COG0519	Catalyzes the synthesis of GMP from XMP
G3W92_RS13300	COG3328	transposase activity
G3W92_RS13325	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS13335	COG1012	belongs to the aldehyde dehydrogenase family
G3W92_RS13340	COG2186	Transcriptional regulator
G3W92_RS13395	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W92_RS13400	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
G3W92_RS13405	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
G3W92_RS13450	COG1619	proteins homologs of microcin C7 resistance protein MccF
G3W92_RS13465	COG3585	molybdate ion transport
G3W92_RS13475	COG3158	transport of potassium into the cell
G3W92_RS13480	COG3181	Tripartite tricarboxylate transporter family receptor
G3W92_RS13490	COG2188	Transcriptional regulator
G3W92_RS13580	COG0084	hydrolase, TatD family'
G3W92_RS13595	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
G3W92_RS13600	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
G3W92_RS13640	COG2183	response to ionizing radiation
G3W92_RS13655	COG0534	Mate efflux family protein
G3W92_RS13735	COG0477	Major facilitator Superfamily
G3W92_RS13740	COG2814	Major facilitator Superfamily
G3W92_RS13745	COG2814	Major facilitator Superfamily
G3W92_RS13775	COG1960	acyl-CoA dehydrogenase activity
G3W92_RS13780	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
G3W92_RS13785	COG4638	Rieske (2fe-2S)
G3W92_RS13800	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS13815	COG3008	intermembrane lipid transfer
G3W92_RS13815	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G3W92_RS13820	COG2995	paraquat-inducible protein a
G3W92_RS13825	COG2995	paraquat-inducible protein a
G3W92_RS13835	COG5507	3-demethylubiquinone-9 3-methyltransferase
G3W92_RS13850	COG1960	acyl-CoA dehydrogenase activity
G3W92_RS13855	COG2130	NADP-dependent
G3W92_RS13875	COG1960	acyl-CoA dehydrogenase activity
G3W92_RS13880	COG0183	Belongs to the thiolase family
G3W92_RS13885	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G3W92_RS13890	COG1024	Enoyl-CoA hydratase
G3W92_RS13890	COG1250	3-hydroxyacyl-CoA dehydrogenase
G3W92_RS13895	COG1129	ABC transporter
G3W92_RS13900	COG0411	ABC transporter
G3W92_RS13925	COG0318	PFAM AMP-dependent synthetase and ligase
G3W92_RS13930	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
G3W92_RS13935	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G3W92_RS13940	COG2917	probably involved in intracellular septation
G3W92_RS13950	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G3W92_RS13955	COG0047	phosphoribosylformylglycinamidine synthase activity
G3W92_RS13955	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
G3W92_RS13960	COG0024	Methionine aminopeptidase
G3W92_RS13965	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
G3W92_RS13970	COG0765	amino acid transport
G3W92_RS13975	COG4597	amino acid ABC transporter
G3W92_RS13980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G3W92_RS13985	COG2259	Doxx family
G3W92_RS13990	COG0242	peptide deformylase activity
G3W92_RS14000	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
G3W92_RS14010	COG1196	nuclear chromosome segregation
G3W92_RS14025	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
G3W92_RS14030	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
G3W92_RS14035	COG4208	sulfate ABC transporter
G3W92_RS14045	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
G3W92_RS14055	COG0450	alkyl hydroperoxide reductase
G3W92_RS14065	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
G3W92_RS14070	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G3W92_RS14085	COG1045	serine acetyltransferase
G3W92_RS14095	COG0431	NADPH-dependent FMN reductase
G3W92_RS14100	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
G3W92_RS14105	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
G3W92_RS14110	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G3W92_RS14110	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
G3W92_RS14120	COG1272	protein, Hemolysin III
G3W92_RS14130	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
G3W92_RS14135	COG3383	formate dehydrogenase (NAD+) activity
G3W92_RS14170	COG0175	sulfate reduction
G3W92_RS14175	COG0175	sulfate reduction
G3W92_RS14180	COG2895	sulfate adenylyltransferase (ATP) activity
G3W92_RS14185	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
G3W92_RS14190	COG0492	ferredoxin-NADP+ reductase activity
G3W92_RS14195	COG0671	phosphoesterase, PA-phosphatase related
G3W92_RS14205	COG0351	phosphomethylpyrimidine kinase
G3W92_RS14220	COG2022	thiamine diphosphate biosynthetic process
G3W92_RS14230	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
G3W92_RS14230	COG2755	lipolytic protein G-D-S-L family
G3W92_RS14260	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G3W92_RS14285	COG0318	PFAM AMP-dependent synthetase and ligase
G3W92_RS14295	COG2175	clavaminate synthase activity
G3W92_RS14320	COG1024	Enoyl-CoA hydratase
G3W92_RS14325	COG1960	acyl-CoA dehydrogenase activity
G3W92_RS14330	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W92_RS14345	COG1024	Enoyl-CoA hydratase
G3W92_RS14370	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G3W92_RS14375	COG0642	Histidine kinase
G3W92_RS14380	COG0745	RESPONSE REGULATOR receiver
G3W92_RS14385	COG1414	Transcriptional regulator
G3W92_RS14390	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G3W92_RS14400	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
G3W92_RS14405	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
G3W92_RS14410	COG1414	Transcriptional regulator
G3W92_RS14420	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G3W92_RS14425	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G3W92_RS14430	COG1183	phosphatidylcholine synthase activity
G3W92_RS14435	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
G3W92_RS14440	COG0440	acetolactate synthase activity
G3W92_RS14445	COG0028	Belongs to the TPP enzyme family
G3W92_RS14470	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
G3W92_RS14480	COG0347	Belongs to the P(II) protein family
G3W92_RS14500	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
G3W92_RS14530	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G3W92_RS14575	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
G3W92_RS14580	COG0746	molybdenum cofactor guanylyltransferase activity
G3W92_RS14590	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G3W92_RS14590	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G3W92_RS14595	COG0328	RNA-DNA hybrid ribonuclease activity
G3W92_RS14610	COG0741	lytic transglycosylase activity
G3W92_RS14610	COG1388	LysM domain
G3W92_RS14615	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3W92_RS14625	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G3W92_RS14635	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
G3W92_RS14640	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
G3W92_RS14645	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
G3W92_RS14730	COG0493	'glutamate synthase
G3W92_RS14730	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
G3W92_RS14735	COG1074	ATP-dependent DNA helicase activity
G3W92_RS14750	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
G3W92_RS14755	COG0673	inositol 2-dehydrogenase activity
G3W92_RS14760	COG0254	rRNA binding
G3W92_RS14770	COG0534	Mate efflux family protein
G3W92_RS14775	COG5002	protein histidine kinase activity
G3W92_RS14790	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
G3W92_RS14795	COG0581	inorganic phosphate transmembrane transporter activity
G3W92_RS14800	COG0573	inorganic phosphate transmembrane transporter activity
G3W92_RS14805	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
G3W92_RS14810	COG0248	Ppx GppA phosphatase
G3W92_RS14830	COG3634	alkyl hydroperoxide reductase activity
G3W92_RS14835	COG0625	glutathione transferase activity
G3W92_RS14865	COG1522	sequence-specific DNA binding
G3W92_RS14880	COG4993	Dehydrogenase
G3W92_RS14905	COG2188	Transcriptional regulator
G3W92_RS14915	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3W92_RS14930	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS14940	COG0183	Belongs to the thiolase family
G3W92_RS14950	COG0439	Biotin carboxylase
G3W92_RS14970	COG0156	8-amino-7-oxononanoate synthase activity
G3W92_RS14980	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
G3W92_RS14985	COG2124	cytochrome p450
G3W92_RS14990	COG1309	transcriptional regulator
G3W92_RS14995	COG1172	Belongs to the binding-protein-dependent transport system permease family
G3W92_RS15005	COG0410	ABC transporter
G3W92_RS15010	COG0411	ABC transporter
G3W92_RS15020	COG1335	isochorismatase
G3W92_RS15050	COG0583	DNA-binding transcription factor activity
G3W92_RS15055	COG0277	FAD linked oxidase domain protein
G3W92_RS15065	COG0247	lactate metabolic process
G3W92_RS15075	COG3119	arylsulfatase activity
G3W92_RS15110	COG2149	membrane
G3W92_RS15125	COG0726	polysaccharide deacetylase
G3W92_RS15130	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G3W92_RS15130	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
G3W92_RS15150	COG2076	Multidrug Resistance protein
G3W92_RS15155	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
G3W92_RS15165	COG0667	Aldo Keto reductase
G3W92_RS15180	COG3181	Tripartite tricarboxylate transporter family receptor
G3W92_RS15195	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS15225	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
G3W92_RS15225	COG1199	ATP-dependent helicase activity
G3W92_RS15245	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
G3W92_RS15250	COG0366	Alpha amylase catalytic
G3W92_RS15255	COG0366	Alpha amylase catalytic
G3W92_RS15270	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
G3W92_RS15275	COG1640	4-alpha-glucanotransferase
G3W92_RS15285	COG1414	Transcriptional regulator
G3W92_RS15295	COG0243	molybdopterin cofactor binding
G3W92_RS15305	COG1024	Enoyl-CoA hydratase
G3W92_RS15310	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W92_RS15315	COG3181	Tripartite tricarboxylate transporter family receptor
G3W92_RS15320	COG0318	PFAM AMP-dependent synthetase and ligase
G3W92_RS15335	COG0318	PFAM AMP-dependent synthetase and ligase
G3W92_RS15345	COG1024	Enoyl-CoA hydratase
G3W92_RS15380	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
G3W92_RS15395	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
G3W92_RS15400	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W92_RS15405	COG3181	Tripartite tricarboxylate transporter family receptor
G3W92_RS15415	COG1024	Enoyl-CoA hydratase
G3W92_RS15435	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G3W92_RS15435	COG0473	3-isopropylmalate dehydrogenase activity
G3W92_RS15475	COG1129	ABC transporter
G3W92_RS15485	COG1053	succinate dehydrogenase
G3W92_RS15490	COG0318	PFAM AMP-dependent synthetase and ligase
G3W92_RS15505	COG4221	oxidoreductase activity
G3W92_RS15540	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS15545	COG4689	acetoacetate decarboxylase
G3W92_RS15580	COG2188	Transcriptional regulator
G3W92_RS15590	COG2308	Evidence 4 Homologs of previously reported genes of
G3W92_RS15610	COG1305	Transglutaminase-like
G3W92_RS15620	COG1522	sequence-specific DNA binding
G3W92_RS15630	COG1280	lysine exporter protein (LysE YggA)
G3W92_RS15635	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
G3W92_RS15655	COG1012	belongs to the aldehyde dehydrogenase family
G3W92_RS15665	COG1024	Enoyl-CoA hydratase
G3W92_RS15670	COG1609	Transcriptional regulator
G3W92_RS15680	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G3W92_RS15690	COG1126	abc transporter atp-binding protein
G3W92_RS15705	COG0765	amino acid transport
G3W92_RS15740	COG0739	heme binding
G3W92_RS15740	COG0741	lytic transglycosylase activity
G3W92_RS15740	COG1196	nuclear chromosome segregation
G3W92_RS15775	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G3W92_RS15780	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
G3W92_RS15785	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
G3W92_RS15800	COG2850	peptidyl-arginine hydroxylation
G3W92_RS15805	COG1047	Peptidyl-prolyl cis-trans
G3W92_RS15820	COG0583	DNA-binding transcription factor activity
G3W92_RS15825	COG0756	dUTP diphosphatase activity
G3W92_RS15835	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
G3W92_RS15840	COG0504	CTP synthase activity
G3W92_RS15845	COG2877	3-deoxy-8-phosphooctulonate synthase activity
G3W92_RS15855	COG0148	phosphopyruvate hydratase activity
G3W92_RS15860	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
G3W92_RS15875	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
G3W92_RS15885	COG2833	Protein of unknown function (DUF455)
G3W92_RS15900	COG4974	Belongs to the 'phage' integrase family
G3W92_RS15905	COG3181	Tripartite tricarboxylate transporter family receptor
G3W92_RS15920	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
G3W92_RS15925	COG0802	atpase or kinase
G3W92_RS15930	COG0860	N-Acetylmuramoyl-L-alanine amidase
G3W92_RS15950	COG0586	Pfam SNARE associated Golgi protein
G3W92_RS15955	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS15965	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
G3W92_RS15975	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
G3W92_RS15980	COG4181	ATPase activity
G3W92_RS15985	COG0583	DNA-binding transcription factor activity
G3W92_RS15990	COG3181	Tripartite tricarboxylate transporter family receptor
G3W92_RS16020	COG0583	DNA-binding transcription factor activity
G3W92_RS16040	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
G3W92_RS16050	COG3795	YCII-related domain
G3W92_RS16055	COG4941	Belongs to the sigma-70 factor family
G3W92_RS16105	COG1566	PFAM secretion protein HlyD family protein
G3W92_RS16110	COG1538	Outer membrane efflux protein
G3W92_RS16115	COG1846	Transcriptional regulator
G3W92_RS16120	COG1132	(ABC) transporter
G3W92_RS16130	COG0494	nUDIX hydrolase
G3W92_RS16140	COG1007	ATP synthesis coupled electron transport
G3W92_RS16155	COG0713	ATP synthesis coupled electron transport
G3W92_RS16165	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G3W92_RS16170	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
G3W92_RS16175	COG1034	ATP synthesis coupled electron transport
G3W92_RS16190	COG0649	NAD binding
G3W92_RS16195	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G3W92_RS16200	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G3W92_RS16205	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G3W92_RS16220	COG0149	triose-phosphate isomerase activity
G3W92_RS16225	COG0604	alcohol dehydrogenase
G3W92_RS16225	COG4221	oxidoreductase activity
G3W92_RS16225	COG3321	synthase
G3W92_RS16225	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G3W92_RS16235	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
G3W92_RS16240	COG0436	Aminotransferase
G3W92_RS16245	COG0683	leucine binding
G3W92_RS16260	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
G3W92_RS16265	COG3707	response regulator
G3W92_RS16270	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G3W92_RS16275	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3W92_RS16280	COG1116	anion transmembrane transporter activity
G3W92_RS16290	COG2223	nitrite transmembrane transporter activity
G3W92_RS16295	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G3W92_RS16305	COG0243	molybdopterin cofactor binding
G3W92_RS16310	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
G3W92_RS16325	COG2081	HI0933 family
G3W92_RS16330	COG0828	Belongs to the bacterial ribosomal protein bS21 family
G3W92_RS16340	COG0494	nUDIX hydrolase
G3W92_RS16345	COG0312	modulator of DNA gyrase
G3W92_RS16350	COG3028	Belongs to the UPF0307 family
G3W92_RS16355	COG0521	Mo-molybdopterin cofactor biosynthetic process
G3W92_RS16360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G3W92_RS16370	COG0765	amino acid transport
G3W92_RS16375	COG0765	amino acid transport
G3W92_RS16380	COG4221	oxidoreductase activity
G3W92_RS16385	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
G3W92_RS16395	COG1984	allophanate hydrolase subunit 2
G3W92_RS16400	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
G3W92_RS16410	COG0511	ligase activity, forming carbon-carbon bonds
G3W92_RS16420	COG0436	Aminotransferase
G3W92_RS16425	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G3W92_RS16435	COG0583	DNA-binding transcription factor activity
G3W92_RS16460	COG1131	(ABC) transporter
G3W92_RS16485	COG0436	Aminotransferase
G3W92_RS16495	COG3265	gluconokinase activity
G3W92_RS16500	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS16505	COG1063	alcohol dehydrogenase
G3W92_RS16510	COG1045	serine acetyltransferase
G3W92_RS16525	COG1289	transmembrane transporter activity
G3W92_RS16545	COG2375	cellular response to nickel ion
G3W92_RS16570	COG2159	amidohydrolase
G3W92_RS16590	COG0583	DNA-binding transcription factor activity
G3W92_RS16595	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
G3W92_RS16610	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G3W92_RS16620	COG0583	DNA-binding transcription factor activity
G3W92_RS16625	COG3119	arylsulfatase activity
G3W92_RS16630	COG3181	Tripartite tricarboxylate transporter family receptor
G3W92_RS16635	COG1968	undecaprenyl-diphosphatase activity
G3W92_RS16645	COG3246	L-lysine catabolic process to acetate
G3W92_RS16655	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W92_RS16660	COG2301	Belongs to the HpcH HpaI aldolase family
G3W92_RS16680	COG1802	Transcriptional regulator
G3W92_RS16690	COG1024	Enoyl-CoA hydratase
G3W92_RS16705	COG1360	Flagellar Motor Protein
G3W92_RS16735	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G3W92_RS16740	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G3W92_RS16765	COG2972	Histidine kinase
G3W92_RS16780	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G3W92_RS16805	COG0411	ABC transporter
G3W92_RS16830	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
G3W92_RS16845	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS16855	COG2918	glutathione biosynthetic process
G3W92_RS16860	COG0400	carboxylic ester hydrolase activity
G3W92_RS16870	COG0583	DNA-binding transcription factor activity
G3W92_RS16915	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
G3W92_RS16945	COG2354	Protein conserved in bacteria
G3W92_RS16955	COG4628	conserved protein (DUF2132)
G3W92_RS16970	COG0564	pseudouridine synthase activity
G3W92_RS16975	COG0589	response to stress
G3W92_RS16990	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
G3W92_RS16995	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G3W92_RS17000	COG1252	NADH dehydrogenase
G3W92_RS17010	COG0318	PFAM AMP-dependent synthetase and ligase
G3W92_RS17015	COG1764	response to oxidative stress
G3W92_RS17030	COG0789	Transcriptional regulator
G3W92_RS17040	COG3191	aminopeptidase activity
G3W92_RS17050	COG0488	(ABC) transporter
G3W92_RS17055	COG0513	Belongs to the DEAD box helicase family
G3W92_RS17060	COG3842	ATPase activity
G3W92_RS17070	COG1175	transmembrane transport
G3W92_RS17080	COG2186	Transcriptional regulator
G3W92_RS17085	COG3734	2-keto-3-deoxy-galactonokinase
G3W92_RS17090	COG0800	Aldolase
G3W92_RS17100	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
G3W92_RS17115	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
G3W92_RS17120	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G3W92_RS17190	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS17205	COG1960	acyl-CoA dehydrogenase activity
G3W92_RS17210	COG1960	acyl-CoA dehydrogenase activity
G3W92_RS17215	COG2030	dehydratase
G3W92_RS17245	COG1595	DNA-templated transcription, initiation
G3W92_RS17255	COG3474	cytochrome
G3W92_RS17260	COG0302	gtp cyclohydrolase
G3W92_RS17265	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS17290	COG0346	lactoylglutathione lyase activity
G3W92_RS17305	COG0800	Aldolase
G3W92_RS17330	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
G3W92_RS17335	COG0259	pyridoxamine-phosphate oxidase activity
G3W92_RS17350	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G3W92_RS17355	COG2301	Belongs to the HpcH HpaI aldolase family
G3W92_RS17370	COG3618	amidohydrolase
G3W92_RS17385	COG4772	TonB-dependent receptor
G3W92_RS17395	COG2986	histidine ammonia-lyase
G3W92_RS17400	COG1309	transcriptional regulator
G3W92_RS17405	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
G3W92_RS17420	COG2207	Transcriptional regulator
G3W92_RS17425	COG0318	PFAM AMP-dependent synthetase and ligase
G3W92_RS17435	COG2030	dehydratase
G3W92_RS17460	COG0235	Class ii aldolase
G3W92_RS17505	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G3W92_RS17510	COG2863	cytochrome
G3W92_RS17515	COG1529	Aldehyde oxidase and xanthine dehydrogenase
G3W92_RS17515	COG2010	Cytochrome c
G3W92_RS17530	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G3W92_RS17535	COG1309	transcriptional regulator
G3W92_RS17555	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G3W92_RS17565	COG2217	Heavy metal translocating P-type atpase
G3W92_RS17570	COG0789	Transcriptional regulator
G3W92_RS17605	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
G3W92_RS17610	COG2301	Belongs to the HpcH HpaI aldolase family
G3W92_RS17630	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G3W92_RS17645	COG1286	toxin biosynthetic process
G3W92_RS17655	COG0285	dihydrofolate synthase activity
G3W92_RS17660	COG1393	Belongs to the ArsC family
G3W92_RS17670	COG3123	guanosine phosphorylase activity
G3W92_RS17675	COG0137	argininosuccinate synthase activity
G3W92_RS17680	COG0812	UDP-N-acetylmuramate dehydrogenase activity
G3W92_RS17685	COG1666	GTP binding
G3W92_RS17695	COG0251	oxidation-reduction process
G3W92_RS17700	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
G3W92_RS17705	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
G3W92_RS17710	COG0667	Aldo Keto reductase
G3W92_RS17720	COG3850	Histidine kinase
G3W92_RS17720	COG2205	protein histidine kinase activity
G3W92_RS17720	COG3437	response regulator, receiver
G3W92_RS17720	COG4999	Histidine kinase
G3W92_RS17725	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
G3W92_RS17735	COG0784	Response regulator, receiver
G3W92_RS17735	COG2205	protein histidine kinase activity
G3W92_RS17745	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G3W92_RS17750	COG0308	aminopeptidase N
G3W92_RS17755	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
G3W92_RS17790	COG0326	Molecular chaperone. Has ATPase activity
G3W92_RS17815	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
G3W92_RS17870	COG1403	HNH endonuclease
G3W92_RS17910	COG0305	Participates in initiation and elongation during chromosome replication
G3W92_RS17940	COG0582	viral genome integration into host DNA
G3W92_RS18015	COG3181	Tripartite tricarboxylate transporter family receptor
G3W92_RS18020	COG0583	DNA-binding transcription factor activity
G3W92_RS18045	COG0745	RESPONSE REGULATOR receiver
G3W92_RS18050	COG2205	protein histidine kinase activity
G3W92_RS18065	COG0840	transmembrane signaling receptor activity
G3W92_RS18070	COG0745	RESPONSE REGULATOR receiver
G3W92_RS18080	COG0643	Histidine kinase
G3W92_RS18080	COG2198	Histidine kinase
G3W92_RS18085	COG0840	transmembrane signaling receptor activity
G3W92_RS18090	COG0835	chemotaxis
G3W92_RS18120	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
G3W92_RS18125	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
G3W92_RS18130	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
G3W92_RS18135	COG0745	RESPONSE REGULATOR receiver
G3W92_RS18145	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
G3W92_RS18150	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
G3W92_RS18160	COG0643	Histidine kinase
G3W92_RS18160	COG2198	Histidine kinase
G3W92_RS18205	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
G3W92_RS18215	COG1677	Flagellar hook-basal body complex protein FliE
G3W92_RS18220	COG1766	The M ring may be actively involved in energy transduction
G3W92_RS18225	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
G3W92_RS18250	COG1580	Controls the rotational direction of flagella during chemotaxis
G3W92_RS18255	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
G3W92_RS18270	COG1338	Plays a role in the flagellum-specific transport system
G3W92_RS18275	COG1987	bacterial-type flagellum assembly
G3W92_RS18295	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G3W92_RS18325	COG1256	bacterial-type flagellum assembly
G3W92_RS18330	COG0840	transmembrane signaling receptor activity
G3W92_RS18340	COG0835	chemotaxis
G3W92_RS18345	COG0840	transmembrane signaling receptor activity
G3W92_RS18350	COG0835	chemotaxis
G3W92_RS18355	COG1705	Flagellar rod assembly protein muramidase FlgJ
G3W92_RS18355	COG3951	Flagellar rod assembly protein muramidase FlgJ
G3W92_RS18360	COG1706	bacterial-type flagellum-dependent cell motility
G3W92_RS18365	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
G3W92_RS18370	COG4786	Flagellar basal body rod
G3W92_RS18385	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
G3W92_RS18390	COG1558	bacterial-type flagellum-dependent cell motility
G3W92_RS18395	COG1815	bacterial-type flagellum-dependent cell motility
G3W92_RS18415	COG0604	alcohol dehydrogenase
G3W92_RS18420	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
G3W92_RS18440	COG0583	DNA-binding transcription factor activity
G3W92_RS18470	COG1250	3-hydroxyacyl-CoA dehydrogenase
G3W92_RS18480	COG0318	PFAM AMP-dependent synthetase and ligase
G3W92_RS18490	COG3243	poly(R)-hydroxyalkanoic acid synthase
G3W92_RS18500	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS18520	COG3302	dmso reductase anchor subunit
G3W92_RS18525	COG0437	4 iron, 4 sulfur cluster binding
G3W92_RS18530	COG0243	molybdopterin cofactor binding
G3W92_RS18535	COG0583	DNA-binding transcription factor activity
G3W92_RS18560	COG1414	Transcriptional regulator
G3W92_RS18585	COG1012	belongs to the aldehyde dehydrogenase family
G3W92_RS18590	COG0318	PFAM AMP-dependent synthetase and ligase
G3W92_RS18610	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS18615	COG0179	Fumarylacetoacetate (FAA) hydrolase
G3W92_RS18620	COG3181	Tripartite tricarboxylate transporter family receptor
G3W92_RS18645	COG1414	Transcriptional regulator
G3W92_RS18650	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
G3W92_RS18655	COG0477	Major facilitator Superfamily
G3W92_RS18665	COG1609	Transcriptional regulator
G3W92_RS18670	COG1082	Xylose isomerase domain protein TIM barrel
G3W92_RS18695	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3W92_RS18700	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G3W92_RS18710	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3W92_RS18715	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
G3W92_RS18730	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3W92_RS18735	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
G3W92_RS18740	COG4521	taurine ABC transporter
G3W92_RS18745	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G3W92_RS18765	COG0601	transmembrane transport
G3W92_RS18770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G3W92_RS18775	COG0444	Belongs to the ABC transporter superfamily
G3W92_RS18780	COG4608	Belongs to the ABC transporter superfamily
G3W92_RS18800	COG0247	lactate metabolic process
G3W92_RS18805	COG1592	Rubrerythrin
G3W92_RS18815	COG2197	response regulator
G3W92_RS18820	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G3W92_RS18825	COG1253	flavin adenine dinucleotide binding
G3W92_RS18830	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
G3W92_RS18835	COG0513	Belongs to the DEAD box helicase family
G3W92_RS18850	COG2321	neutral zinc metallopeptidase
G3W92_RS18860	COG0717	Belongs to the dCTP deaminase family
G3W92_RS18865	COG0402	S-adenosylhomocysteine deaminase activity
G3W92_RS18885	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
G3W92_RS18910	COG2252	PERMEase
G3W92_RS18920	COG1529	Aldehyde oxidase and xanthine dehydrogenase
G3W92_RS18945	COG1850	ribulose-bisphosphate carboxylase activity
G3W92_RS18955	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
G3W92_RS18960	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G3W92_RS18965	COG1609	Transcriptional regulator
G3W92_RS18980	COG0583	DNA-binding transcription factor activity
G3W92_RS18995	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS19005	COG2030	dehydratase
G3W92_RS19015	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W92_RS19025	COG1960	acyl-CoA dehydrogenase activity
G3W92_RS19035	COG1024	Enoyl-CoA hydratase
G3W92_RS19040	COG3181	Tripartite tricarboxylate transporter family receptor
G3W92_RS19050	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G3W92_RS19060	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
G3W92_RS19070	COG0667	Aldo Keto reductase
G3W92_RS19080	COG0438	transferase activity, transferring glycosyl groups
G3W92_RS19110	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
G3W92_RS19110	COG3608	succinylglutamate desuccinylase aspartoacylase
G3W92_RS19170	COG0667	Aldo Keto reductase
G3W92_RS19200	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W92_RS19205	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G3W92_RS19240	COG2084	Dehydrogenase
G3W92_RS19245	COG0745	RESPONSE REGULATOR receiver
G3W92_RS19250	COG0642	Histidine kinase
G3W92_RS19265	COG0671	phosphoesterase, PA-phosphatase related
G3W92_RS19270	COG0463	Glycosyl transferase, family 2
G3W92_RS19275	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
G3W92_RS19285	COG1116	anion transmembrane transporter activity
G3W92_RS19290	COG0390	transport system, permease component
G3W92_RS19300	COG1609	Transcriptional regulator
G3W92_RS19320	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G3W92_RS19330	COG1950	PFAM Membrane protein of
G3W92_RS19335	COG1012	belongs to the aldehyde dehydrogenase family
G3W92_RS19340	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
G3W92_RS19345	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G3W92_RS19360	COG1122	ATPase activity
G3W92_RS19380	COG0559	Belongs to the binding-protein-dependent transport system permease family
G3W92_RS19390	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G3W92_RS19395	COG2151	metal-sulfur cluster biosynthetic enzyme
G3W92_RS19400	COG3396	Phenylacetate-CoA oxygenase
G3W92_RS19405	COG3460	Phenylacetate-CoA oxygenase
G3W92_RS19410	COG3396	Phenylacetate-CoA oxygenase
G3W92_RS19420	COG2050	protein possibly involved in aromatic compounds catabolism
G3W92_RS19425	COG1024	Enoyl-CoA hydratase
G3W92_RS19435	COG1309	transcriptional regulator
G3W92_RS19445	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
G3W92_RS19490	COG0392	lysyltransferase activity
G3W92_RS19495	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
G3W92_RS19500	COG0142	geranyltranstransferase activity
G3W92_RS19505	COG1722	exodeoxyribonuclease VII activity
G3W92_RS19550	COG3360	Dodecin
G3W92_RS19595	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
G3W92_RS19605	COG1012	belongs to the aldehyde dehydrogenase family
G3W92_RS19610	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
G3W92_RS19630	COG1176	ABC-type spermidine putrescine transport system, permease component I
G3W92_RS19635	COG3842	ATPase activity
G3W92_RS19650	COG0210	DNA helicase
G3W92_RS19655	COG0516	GMP reductase activity
G3W92_RS19670	COG0300	oxidoreductase activity
G3W92_RS19695	COG3851	Histidine kinase
G3W92_RS19735	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
G3W92_RS19740	COG0028	Belongs to the TPP enzyme family
G3W92_RS19765	COG0513	Belongs to the DEAD box helicase family
G3W92_RS19770	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
G3W92_RS19775	COG0501	Belongs to the peptidase M48B family
G3W92_RS19780	COG2154	pterin-4-alpha-carbinolamine dehydratase
G3W92_RS19785	COG1162	GTPase activity
G3W92_RS19790	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
G3W92_RS19795	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
G3W92_RS19805	COG0335	large ribosomal subunit rRNA binding
G3W92_RS19810	COG0336	Belongs to the RNA methyltransferase TrmD family
G3W92_RS19815	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
G3W92_RS19820	COG0228	four-way junction DNA binding
G3W92_RS19835	COG0306	phosphate transporter
G3W92_RS19840	COG1392	Phosphate transport regulator
G3W92_RS19850	COG0617	tRNA 3'-terminal CCA addition
G3W92_RS19855	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
G3W92_RS19860	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
G3W92_RS19875	COG1917	Cupin 2, conserved barrel domain protein
G3W92_RS19875	COG4977	sequence-specific DNA binding
G3W92_RS19895	COG0728	peptidoglycan biosynthetic process
G3W92_RS19900	COG0268	Binds directly to 16S ribosomal RNA
G3W92_RS19910	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G3W92_RS19915	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
G3W92_RS19920	COG3550	peptidyl-serine autophosphorylation
G3W92_RS19925	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
G3W92_RS19935	COG3483	tryptophan 2,3-dioxygenase activity
G3W92_RS19945	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G3W92_RS19955	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
G3W92_RS19955	COG1918	ferrous iron import across plasma membrane
G3W92_RS19970	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
G3W92_RS19985	COG1049	propionate catabolic process, 2-methylcitrate cycle
G3W92_RS20000	COG4106	trans-aconitate 2-methyltransferase activity
G3W92_RS20005	COG0039	L-malate dehydrogenase activity
G3W92_RS20010	COG2188	Transcriptional regulator
G3W92_RS20025	COG1053	succinate dehydrogenase
G3W92_RS20030	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
G3W92_RS20035	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
G3W92_RS20040	COG0372	Belongs to the citrate synthase family
G3W92_RS20050	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
G3W92_RS20055	COG0066	3-isopropylmalate dehydratase activity
G3W92_RS20060	COG0473	3-isopropylmalate dehydrogenase activity
G3W92_RS20065	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
G3W92_RS20075	COG0101	tRNA pseudouridine synthase activity
G3W92_RS20080	COG0135	phosphoribosylanthranilate isomerase activity
G3W92_RS20085	COG0133	tryptophan synthase activity
G3W92_RS20090	COG0159	tryptophan synthase activity
G3W92_RS20095	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
G3W92_RS20100	COG0762	integral membrane protein
G3W92_RS20110	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
G3W92_RS20115	COG0443	Heat shock 70 kDa protein
G3W92_RS20120	COG1451	nucleotide metabolic process
G3W92_RS20125	COG1472	Belongs to the glycosyl hydrolase 3 family
G3W92_RS20130	COG0736	holo-[acyl-carrier-protein] synthase activity
G3W92_RS20135	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
G3W92_RS20140	COG1381	Involved in DNA repair and RecF pathway recombination
G3W92_RS20145	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
G3W92_RS20150	COG0571	ribonuclease III activity
G3W92_RS20160	COG0681	Belongs to the peptidase S26 family
G3W92_RS20165	COG0481	GTPase activity
G3W92_RS20170	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G3W92_RS20195	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G3W92_RS20200	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G3W92_RS20205	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS20215	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G3W92_RS20220	COG0416	fatty acid biosynthetic process
G3W92_RS20225	COG0333	Belongs to the bacterial ribosomal protein bL32 family
G3W92_RS20230	COG1399	metal-binding, possibly nucleic acid-binding protein
G3W92_RS20235	COG0424	maF-like protein
G3W92_RS20240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
G3W92_RS20245	COG2223	nitrite transmembrane transporter activity
G3W92_RS20260	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G3W92_RS20270	COG1530	ribonuclease E activity
G3W92_RS20285	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G3W92_RS20305	COG0297	glycogen (starch) synthase activity
G3W92_RS20340	COG0181	hydroxymethylbilane synthase activity
G3W92_RS20345	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
G3W92_RS20355	COG3459	Glycosyltransferase 36 associated
G3W92_RS20370	COG3275	phosphorelay sensor kinase activity
G3W92_RS20375	COG0165	Argininosuccinate lyase
G3W92_RS20415	COG0438	transferase activity, transferring glycosyl groups
G3W92_RS20430	COG2197	response regulator
G3W92_RS20455	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G3W92_RS20465	COG0583	DNA-binding transcription factor activity
G3W92_RS20470	COG4948	Mandelate Racemase Muconate Lactonizing
G3W92_RS20480	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
G3W92_RS20490	COG0477	Major facilitator Superfamily
G3W92_RS20500	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
G3W92_RS20530	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
G3W92_RS20530	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
G3W92_RS20545	COG3022	response to hydroperoxide
G3W92_RS20550	COG0525	valine-tRNA ligase activity
G3W92_RS20565	COG0425	Belongs to the sulfur carrier protein TusA family
G3W92_RS20570	COG2816	NAD+ diphosphatase activity
G3W92_RS20590	COG5001	Diguanylate cyclase
G3W92_RS20590	COG4251	negative regulation of phosphorylation
G3W92_RS20590	COG2203	Gaf domain
G3W92_RS20590	COG3706	GGDEF domain
G3W92_RS20600	COG5002	protein histidine kinase activity
G3W92_RS20600	COG5001	Diguanylate cyclase
G3W92_RS20600	COG3447	MASE1 domain protein
G3W92_RS20605	COG2204	response regulator
G3W92_RS20640	COG1222	aaa ATPase
G3W92_RS20740	COG0559	Belongs to the binding-protein-dependent transport system permease family
G3W92_RS20745	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
G3W92_RS20750	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
G3W92_RS20755	COG1674	ftsk spoiiie
G3W92_RS20765	COG0492	ferredoxin-NADP+ reductase activity
G3W92_RS20770	COG0227	Belongs to the bacterial ribosomal protein bL28 family
G3W92_RS20775	COG0267	Belongs to the bacterial ribosomal protein bL33 family
G3W92_RS20785	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
G3W92_RS20785	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
G3W92_RS20795	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
G3W92_RS20800	COG1960	acyl-CoA dehydrogenase activity
G3W92_RS20835	COG0196	riboflavin kinase activity
G3W92_RS20845	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
G3W92_RS20850	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
G3W92_RS20855	COG1283	sodium-dependent phosphate transmembrane transporter activity
G3W92_RS20865	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS20875	COG0405	Gamma-glutamyltransferase
G3W92_RS20880	COG3181	Tripartite tricarboxylate transporter family receptor
G3W92_RS20885	COG0583	DNA-binding transcription factor activity
G3W92_RS20900	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
G3W92_RS20905	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
G3W92_RS20920	COG0084	hydrolase, TatD family'
G3W92_RS20925	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G3W92_RS20930	COG0714	Associated with various cellular activities
G3W92_RS20940	COG2304	oxidoreductase activity
G3W92_RS20950	COG1959	2 iron, 2 sulfur cluster binding
G3W92_RS20965	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G3W92_RS20970	COG0038	chloride channel
G3W92_RS20985	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
G3W92_RS20990	COG1737	Transcriptional regulator
G3W92_RS21015	COG0601	transmembrane transport
G3W92_RS21025	COG0251	oxidation-reduction process
G3W92_RS21030	COG1201	RNA secondary structure unwinding
G3W92_RS21040	COG1573	uracil-dna glycosylase
G3W92_RS21045	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G3W92_RS21055	COG3842	ATPase activity
G3W92_RS21075	COG0045	succinate-CoA ligase (ADP-forming) activity
G3W92_RS21080	COG1024	Enoyl-CoA hydratase
G3W92_RS21085	COG1024	Enoyl-CoA hydratase
G3W92_RS21095	COG1024	Enoyl-CoA hydratase
G3W92_RS21100	COG2951	lytic endotransglycosylase activity
G3W92_RS21105	COG1136	(ABC) transporter
G3W92_RS21110	COG4591	ABC-type transport system involved in lipoprotein release permease component
G3W92_RS21120	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
G3W92_RS21135	COG0642	Histidine kinase
G3W92_RS21160	COG0784	Response regulator, receiver
G3W92_RS21160	COG2198	Histidine kinase
G3W92_RS21160	COG5002	protein histidine kinase activity
G3W92_RS21165	COG0831	urea catabolic process
G3W92_RS21175	COG0832	Belongs to the urease beta subunit family
G3W92_RS21180	COG0804	urea catabolic process
G3W92_RS21190	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
G3W92_RS21195	COG0830	nickel cation binding
G3W92_RS21200	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
G3W92_RS21235	COG1024	Enoyl-CoA hydratase
G3W92_RS21245	COG1414	Transcriptional regulator
G3W92_RS21250	COG3181	Tripartite tricarboxylate transporter family receptor
G3W92_RS21255	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G3W92_RS21280	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G3W92_RS21315	COG0402	S-adenosylhomocysteine deaminase activity
G3W92_RS21320	COG0583	DNA-binding transcription factor activity
G3W92_RS21325	COG1335	isochorismatase
G3W92_RS21330	COG1942	4-Oxalocrotonate Tautomerase
G3W92_RS21355	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
G3W92_RS21360	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3W92_RS21380	COG0523	cobalamin synthesis protein
G3W92_RS21395	COG4948	Mandelate Racemase Muconate Lactonizing
G3W92_RS21405	COG1741	Belongs to the pirin family
G3W92_RS21420	COG0583	DNA-binding transcription factor activity
G3W92_RS21425	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W92_RS21450	COG2020	methyltransferase activity
G3W92_RS21555	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
G3W92_RS21605	COG0635	Involved in the biosynthesis of porphyrin-containing compound
G3W92_RS21610	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
G3W92_RS21615	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
G3W92_RS21625	COG2815	serine threonine protein kinase
G3W92_RS21625	COG0515	serine threonine protein kinase
G3W92_RS21630	COG1561	YicC-like family, N-terminal region
G3W92_RS21635	COG0194	GDP metabolic process
G3W92_RS21640	COG1758	RNA polymerase activity
G3W92_RS21645	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G3W92_RS21660	COG1285	pathogenesis
G3W92_RS21695	COG2860	membrane
G3W92_RS21705	COG1420	regulation of RNA biosynthetic process
G3W92_RS21710	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
G3W92_RS21715	COG0497	DNA recombination
G3W92_RS21720	COG1660	Displays ATPase and GTPase activities
G3W92_RS21725	COG1194	a g-specific adenine glycosylase
G3W92_RS21730	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
G3W92_RS21735	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
G3W92_RS21750	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
G3W92_RS21760	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
G3W92_RS21765	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
G3W92_RS21770	COG0193	aminoacyl-tRNA hydrolase activity
G3W92_RS21780	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
G3W92_RS21790	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G3W92_RS21795	COG0444	Belongs to the ABC transporter superfamily
G3W92_RS21800	COG4608	Belongs to the ABC transporter superfamily
G3W92_RS21805	COG0747	negative chemotaxis
G3W92_RS21810	COG0154	amidase activity
G3W92_RS21820	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
G3W92_RS21825	COG0673	inositol 2-dehydrogenase activity
G3W92_RS21835	COG0583	DNA-binding transcription factor activity
G3W92_RS21850	COG1473	amidohydrolase
G3W92_RS21855	COG0747	negative chemotaxis
G3W92_RS21860	COG0601	transmembrane transport
G3W92_RS21870	COG0444	Belongs to the ABC transporter superfamily
G3W92_RS21880	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
G3W92_RS21910	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
G3W92_RS21920	COG0406	alpha-ribazole phosphatase activity
G3W92_RS21925	COG2267	carboxylic ester hydrolase activity
G3W92_RS21930	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
G3W92_RS21935	COG1984	allophanate hydrolase subunit 2
G3W92_RS21940	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
G3W92_RS21945	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
G3W92_RS21950	COG0742	ribosomal rna small subunit methyltransferase
G3W92_RS21955	COG0612	Peptidase, M16
G3W92_RS21960	COG0612	Peptidase, M16
G3W92_RS21980	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
G3W92_RS21985	COG1999	signal sequence binding
G3W92_RS21990	COG0109	protoheme IX farnesyltransferase activity
G3W92_RS22020	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
G3W92_RS22025	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
G3W92_RS22030	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
G3W92_RS22040	COG2226	methyltransferase
G3W92_RS22045	COG1040	competence protein
G3W92_RS22050	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
G3W92_RS22070	COG2249	NAD(P)H dehydrogenase (quinone) activity
G3W92_RS22090	COG1733	regulation of RNA biosynthetic process
G3W92_RS22100	COG1024	Enoyl-CoA hydratase
G3W92_RS22140	COG1960	acyl-CoA dehydrogenase activity
G3W92_RS22200	COG3485	protocatechuate 3,4-dioxygenase
G3W92_RS22225	COG0183	Belongs to the thiolase family
G3W92_RS22230	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
G3W92_RS22240	COG1414	Transcriptional regulator
G3W92_RS22270	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
G3W92_RS22275	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
G3W92_RS22315	COG1137	ATPase activity
G3W92_RS22325	COG1012	belongs to the aldehyde dehydrogenase family
G3W92_RS22340	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G3W92_RS22355	COG0583	DNA-binding transcription factor activity
G3W92_RS22370	COG0583	DNA-binding transcription factor activity
G3W92_RS22375	COG3485	protocatechuate 3,4-dioxygenase
G3W92_RS22380	COG3485	protocatechuate 3,4-dioxygenase
G3W92_RS22390	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G3W92_RS22440	COG0583	DNA-binding transcription factor activity
G3W92_RS22445	COG1473	amidohydrolase
G3W92_RS22460	COG3181	Tripartite tricarboxylate transporter family receptor
G3W92_RS22470	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W92_RS22475	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W92_RS22515	COG0477	Major facilitator Superfamily
G3W92_RS22530	COG0540	Belongs to the ATCase OTCase family
G3W92_RS22535	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
G3W92_RS22540	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
G3W92_RS22545	COG1678	Uncharacterized ACR, COG1678
G3W92_RS22550	COG0415	Belongs to the DNA photolyase family
G3W92_RS22555	COG0643	Histidine kinase
G3W92_RS22555	COG2198	Histidine kinase
G3W92_RS22560	COG0840	transmembrane signaling receptor activity
G3W92_RS22580	COG1773	rubredoxin
G3W92_RS22590	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
G3W92_RS22600	COG0138	bifunctional purine biosynthesis protein purh
G3W92_RS22610	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
G3W92_RS22615	COG1238	metal cluster binding
G3W92_RS22630	COG0012	GTP binding
G3W92_RS22635	COG0633	Ferredoxin
G3W92_RS22635	COG3217	Mosc domain protein beta barrel domain protein
G3W92_RS22640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G3W92_RS22655	COG1024	Enoyl-CoA hydratase
G3W92_RS22680	COG3181	Tripartite tricarboxylate transporter family receptor
G3W92_RS22685	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W92_RS22690	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS22710	COG1024	Enoyl-CoA hydratase
G3W92_RS22725	COG1960	acyl-CoA dehydrogenase activity
G3W92_RS22730	COG1960	acyl-CoA dehydrogenase activity
G3W92_RS22735	COG0318	PFAM AMP-dependent synthetase and ligase
G3W92_RS22745	COG2084	Dehydrogenase
G3W92_RS22780	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS22785	COG1024	Enoyl-CoA hydratase
G3W92_RS22790	COG0446	pyridine nucleotide-disulphide oxidoreductase
G3W92_RS22790	COG1902	pentaerythritol trinitrate reductase activity
G3W92_RS22795	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
G3W92_RS22800	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS22810	COG1960	acyl-CoA dehydrogenase activity
G3W92_RS22815	COG0583	DNA-binding transcription factor activity
G3W92_RS22820	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W92_RS22825	COG1024	Enoyl-CoA hydratase
G3W92_RS22830	COG1960	acyl-CoA dehydrogenase activity
G3W92_RS22835	COG1960	acyl-CoA dehydrogenase activity
G3W92_RS22860	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G3W92_RS22880	COG0559	Belongs to the binding-protein-dependent transport system permease family
G3W92_RS22890	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS22920	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
G3W92_RS22930	COG2255	four-way junction helicase activity
G3W92_RS22940	COG0632	four-way junction helicase activity
G3W92_RS22945	COG1702	phosphate starvation-inducible protein PhoH
G3W92_RS22950	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
G3W92_RS22955	COG1490	D-aminoacyl-tRNA deacylase activity
G3W92_RS22960	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
G3W92_RS22965	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
G3W92_RS22970	COG0739	heme binding
G3W92_RS22975	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
G3W92_RS22980	COG0477	Major facilitator Superfamily
G3W92_RS22985	COG0316	Belongs to the HesB IscA family
G3W92_RS22990	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
G3W92_RS22995	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
G3W92_RS23000	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
G3W92_RS23005	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
G3W92_RS23020	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
G3W92_RS23025	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
G3W92_RS23045	COG1309	transcriptional regulator
G3W92_RS23070	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3W92_RS23095	COG1309	transcriptional regulator
G3W92_RS23105	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
G3W92_RS23115	COG0477	Major facilitator Superfamily
G3W92_RS23140	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G3W92_RS23155	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
G3W92_RS23165	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G3W92_RS23170	COG0318	PFAM AMP-dependent synthetase and ligase
G3W92_RS23175	COG1960	acyl-CoA dehydrogenase activity
G3W92_RS23190	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G3W92_RS23195	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
G3W92_RS23210	COG3012	SEC-C Motif Domain Protein
G3W92_RS23215	COG1960	acyl-CoA dehydrogenase activity
G3W92_RS23220	COG0183	Belongs to the thiolase family
G3W92_RS23225	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
G3W92_RS23230	COG0288	reversible hydration of carbon dioxide
G3W92_RS23235	COG0789	Transcriptional regulator
G3W92_RS23250	COG0564	pseudouridine synthase activity
G3W92_RS23260	COG2205	protein histidine kinase activity
G3W92_RS23280	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
G3W92_RS23285	COG0751	glycine-tRNA ligase activity
G3W92_RS23290	COG0752	glycyl-tRNA synthetase alpha subunit
G3W92_RS23300	COG0815	Transfers the fatty acyl group on membrane lipoproteins
G3W92_RS23305	COG4535	Mg2 and Co2 transporter CorC
G3W92_RS23315	COG1522	sequence-specific DNA binding
G3W92_RS23330	COG3186	Phenylalanine-4-hydroxylase
G3W92_RS23335	COG0318	PFAM AMP-dependent synthetase and ligase
G3W92_RS23375	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G3W92_RS23380	COG2188	Transcriptional regulator
G3W92_RS23385	COG0697	spore germination
G3W92_RS23390	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G3W92_RS23400	COG0384	phenazine biosynthesis protein PhzF
G3W92_RS23410	COG1280	lysine exporter protein (LysE YggA)
G3W92_RS23415	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
G3W92_RS23420	COG3468	outer membrane autotransporter barrel domain protein
G3W92_RS23420	COG3468	outer membrane autotransporter barrel domain protein
G3W92_RS23445	COG1881	PFAM PEBP family protein
G3W92_RS23460	COG0402	S-adenosylhomocysteine deaminase activity
G3W92_RS23475	COG1609	Transcriptional regulator
G3W92_RS23485	COG4232	protein-disulfide reductase activity
G3W92_RS23490	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G3W92_RS23495	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
G3W92_RS23500	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
G3W92_RS23515	COG0679	Auxin Efflux Carrier
G3W92_RS23520	COG0210	DNA helicase
G3W92_RS23535	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
G3W92_RS23545	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G3W92_RS23565	COG0402	S-adenosylhomocysteine deaminase activity
G3W92_RS23570	COG3181	Tripartite tricarboxylate transporter family receptor
G3W92_RS23585	COG0179	Fumarylacetoacetate (FAA) hydrolase
G3W92_RS23590	COG3181	Tripartite tricarboxylate transporter family receptor
G3W92_RS23595	COG3181	Tripartite tricarboxylate transporter family receptor
G3W92_RS23610	COG0583	DNA-binding transcription factor activity
G3W92_RS23615	COG3181	Tripartite tricarboxylate transporter family receptor
G3W92_RS23635	COG3246	L-lysine catabolic process to acetate
G3W92_RS23640	COG2175	clavaminate synthase activity
G3W92_RS23650	COG2175	clavaminate synthase activity
G3W92_RS23675	COG3181	Tripartite tricarboxylate transporter family receptor
G3W92_RS23680	COG3246	L-lysine catabolic process to acetate
G3W92_RS23690	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3W92_RS23695	COG1116	anion transmembrane transporter activity
G3W92_RS23715	COG0439	Biotin carboxylase
G3W92_RS23725	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W92_RS23730	COG2186	Transcriptional regulator
G3W92_RS23735	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W92_RS23740	COG0511	ligase activity, forming carbon-carbon bonds
G3W92_RS23745	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W92_RS23750	COG0431	NADPH-dependent FMN reductase
G3W92_RS23760	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS23775	COG1960	acyl-CoA dehydrogenase activity
G3W92_RS23785	COG1024	Enoyl-CoA hydratase
G3W92_RS23795	COG0583	DNA-binding transcription factor activity
G3W92_RS23800	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G3W92_RS23805	COG3181	Tripartite tricarboxylate transporter family receptor
G3W92_RS23810	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G3W92_RS23815	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G3W92_RS23815	COG0426	domain, Protein
G3W92_RS23820	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS23835	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
G3W92_RS23845	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G3W92_RS23890	COG3971	2-oxopent-4-enoate hydratase activity
G3W92_RS23905	COG0583	DNA-binding transcription factor activity
G3W92_RS23920	COG1609	Transcriptional regulator
G3W92_RS23960	COG0148	phosphopyruvate hydratase activity
G3W92_RS23985	COG0179	Fumarylacetoacetate (FAA) hydrolase
G3W92_RS23995	COG0582	viral genome integration into host DNA
G3W92_RS24010	COG4983	Phage plasmid primase, P4 family domain protein
G3W92_RS24030	COG4372	Transposase
G3W92_RS24035	COG3436	PFAM IS66 Orf2 family protein
G3W92_RS24060	COG1902	pentaerythritol trinitrate reductase activity
G3W92_RS24065	COG2814	Major facilitator Superfamily
G3W92_RS24070	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
G3W92_RS24075	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
G3W92_RS24095	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS24100	COG1053	succinate dehydrogenase
G3W92_RS24140	COG1172	Belongs to the binding-protein-dependent transport system permease family
G3W92_RS24145	COG1129	ABC transporter
G3W92_RS24175	COG5377	YqaJ viral recombinase family
G3W92_RS24200	COG1204	response to ionizing radiation
G3W92_RS24250	COG0347	Belongs to the P(II) protein family
G3W92_RS24330	COG0789	Transcriptional regulator
G3W92_RS24340	COG0672	)-iron permease
G3W92_RS24350	COG0784	Response regulator, receiver
G3W92_RS24350	COG2205	protein histidine kinase activity
G3W92_RS24355	COG0789	Transcriptional regulator
G3W92_RS24370	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G3W92_RS24375	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G3W92_RS24435	COG0789	Transcriptional regulator
G3W92_RS24455	COG0640	Transcriptional regulator
G3W92_RS24465	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G3W92_RS24465	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G3W92_RS24470	COG2814	Major facilitator Superfamily
G3W92_RS24500	COG1695	Transcriptional regulator
G3W92_RS24515	COG2948	multi-organism process
G3W92_RS24545	COG3451	type IV secretory pathway VirB4
G3W92_RS24560	COG4962	Type ii secretion system protein e
G3W92_RS24575	COG0583	DNA-binding transcription factor activity
G3W92_RS24580	COG1126	abc transporter atp-binding protein
G3W92_RS24590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G3W92_RS24635	COG1192	Involved in chromosome partitioning
G3W92_RS24660	COG1396	sequence-specific DNA binding
G3W92_RS24670	COG5489	Protein of unknown function (DUF736)
G3W92_RS24690	COG2003	Belongs to the UPF0758 family
G3W92_RS24730	COG4804	nuclease activity
G3W92_RS24735	COG0582	viral genome integration into host DNA
G3W92_RS24745	COG2204	response regulator
G3W92_RS24750	COG5000	phosphorelay sensor kinase activity
G3W92_RS24770	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
G3W92_RS24775	COG0085	RNA polymerase activity
G3W92_RS24780	COG0222	ribosome binding
G3W92_RS24785	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
G3W92_RS24790	COG0081	regulation of translation
G3W92_RS24795	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
G3W92_RS24805	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
G3W92_RS24815	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
G3W92_RS24835	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
G3W92_RS24840	COG0134	indole-3-glycerol-phosphate synthase activity
G3W92_RS24845	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
G3W92_RS24850	COG1280	lysine exporter protein (LysE YggA)
G3W92_RS24880	COG0546	phosphoglycolate phosphatase activity
G3W92_RS24895	COG0745	RESPONSE REGULATOR receiver
G3W92_RS24955	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G3W92_RS24960	COG0436	Aminotransferase
G3W92_RS24965	COG0251	oxidation-reduction process
G3W92_RS24970	COG0384	phenazine biosynthesis protein PhzF
G3W92_RS25040	COG3501	Rhs element vgr protein
G3W92_RS25095	COG0515	serine threonine protein kinase
G3W92_RS25130	COG0154	amidase activity
G3W92_RS25140	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
G3W92_RS25155	COG2205	protein histidine kinase activity
G3W92_RS25230	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
G3W92_RS25270	COG3265	gluconokinase activity
G3W92_RS25295	COG0674	pyruvate-flavodoxin oxidoreductase activity
G3W92_RS25295	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
G3W92_RS25310	COG2967	ApaG domain
G3W92_RS25320	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
G3W92_RS25345	COG0583	DNA-binding transcription factor activity
G3W92_RS25360	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G3W92_RS25365	COG2205	protein histidine kinase activity
G3W92_RS25365	COG0784	Response regulator, receiver
G3W92_RS25365	COG2198	Histidine kinase
G3W92_RS25370	COG2197	response regulator
G3W92_RS25385	COG3181	Tripartite tricarboxylate transporter family receptor
G3W92_RS25400	COG2226	methyltransferase
G3W92_RS25405	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G3W92_RS25410	COG4948	Mandelate Racemase Muconate Lactonizing
G3W92_RS25415	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
G3W92_RS25440	COG0583	DNA-binding transcription factor activity
G3W92_RS25445	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
G3W92_RS25465	COG3181	Tripartite tricarboxylate transporter family receptor
G3W92_RS25485	COG0653	protein targeting
G3W92_RS25490	COG0069	glutamate synthase activity
G3W92_RS25500	COG0783	Belongs to the Dps family
G3W92_RS25505	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G3W92_RS25520	COG2197	response regulator
G3W92_RS25525	COG4585	Histidine kinase
G3W92_RS25535	COG0784	Response regulator, receiver
G3W92_RS25535	COG2205	protein histidine kinase activity
G3W92_RS25540	COG3038	cytochrome b561
G3W92_RS25555	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G3W92_RS25560	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
G3W92_RS25565	COG1137	ATPase activity
G3W92_RS25570	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
G3W92_RS25575	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
G3W92_RS25585	COG0018	arginyl-trna synthetase
G3W92_RS25615	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W92_RS25620	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G3W92_RS25625	COG1414	Transcriptional regulator
G3W92_RS25630	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
G3W92_RS25645	COG2205	protein histidine kinase activity
G3W92_RS25645	COG0784	Response regulator, receiver
G3W92_RS25670	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
G3W92_RS25675	COG0583	DNA-binding transcription factor activity
G3W92_RS25685	COG0205	6-phosphofructokinase activity
G3W92_RS25700	COG2814	Major facilitator Superfamily
G3W92_RS25705	COG0121	glutamine amidotransferase
G3W92_RS25710	COG0189	ligase activity
G3W92_RS25715	COG3135	benzoate transporter
G3W92_RS25720	COG3158	transport of potassium into the cell
G3W92_RS25730	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
G3W92_RS25740	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
G3W92_RS25745	COG0495	leucyl-tRNA aminoacylation
G3W92_RS25750	COG1523	belongs to the glycosyl hydrolase 13 family
G3W92_RS25755	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
G3W92_RS25760	COG0297	glycogen (starch) synthase activity
G3W92_RS25765	COG0058	SHG alpha-glucan phosphorylase activity
G3W92_RS25775	COG1921	L-seryl-tRNASec selenium transferase activity
G3W92_RS25810	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS25820	COG1305	Transglutaminase-like
G3W92_RS25825	COG0583	DNA-binding transcription factor activity
G3W92_RS25840	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
G3W92_RS25845	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G3W92_RS25850	COG0735	belongs to the Fur family
G3W92_RS25855	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
G3W92_RS25865	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
G3W92_RS25870	COG0210	DNA helicase
G3W92_RS25875	COG0598	Magnesium transport protein CorA
G3W92_RS25905	COG4638	Rieske (2fe-2S)
G3W92_RS25910	COG0179	Fumarylacetoacetate (FAA) hydrolase
G3W92_RS25920	COG0028	Belongs to the TPP enzyme family
G3W92_RS25930	COG0747	negative chemotaxis
G3W92_RS25935	COG4608	Belongs to the ABC transporter superfamily
G3W92_RS25940	COG0444	Belongs to the ABC transporter superfamily
G3W92_RS25945	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G3W92_RS25950	COG0601	transmembrane transport
G3W92_RS25955	COG0318	PFAM AMP-dependent synthetase and ligase
G3W92_RS25975	COG0745	RESPONSE REGULATOR receiver
G3W92_RS25990	COG0482	sulfurtransferase activity
G3W92_RS25995	COG0318	PFAM AMP-dependent synthetase and ligase
G3W92_RS26005	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G3W92_RS26015	COG3181	Tripartite tricarboxylate transporter family receptor
G3W92_RS26020	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
G3W92_RS26025	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G3W92_RS26030	COG2721	sulfolactate sulfo-lyase activity
G3W92_RS26035	COG2721	sulfolactate sulfo-lyase activity
G3W92_RS26040	COG2188	Transcriptional regulator
G3W92_RS26055	COG0629	single-stranded DNA binding
G3W92_RS26095	COG0277	FAD linked oxidase domain protein
G3W92_RS26100	COG0745	RESPONSE REGULATOR receiver
G3W92_RS26110	COG3852	Histidine kinase
G3W92_RS26120	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS26135	COG1902	pentaerythritol trinitrate reductase activity
G3W92_RS26200	COG0436	Aminotransferase
G3W92_RS26210	COG0473	3-isopropylmalate dehydrogenase activity
G3W92_RS26210	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G3W92_RS26225	COG3181	Tripartite tricarboxylate transporter family receptor
G3W92_RS26230	COG0583	DNA-binding transcription factor activity
G3W92_RS26245	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3W92_RS26255	COG0596	Alpha beta hydrolase
G3W92_RS26265	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G3W92_RS26275	COG0583	DNA-binding transcription factor activity
G3W92_RS26295	COG0583	DNA-binding transcription factor activity
G3W92_RS26315	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS26325	COG0778	Nitroreductase
G3W92_RS26330	COG3813	Protein conserved in bacteria
G3W92_RS26335	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G3W92_RS26340	COG1946	Acyl-CoA thioesterase
G3W92_RS26345	COG0446	pyridine nucleotide-disulphide oxidoreductase
G3W92_RS26350	COG3181	Tripartite tricarboxylate transporter family receptor
G3W92_RS26355	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G3W92_RS26370	COG0583	DNA-binding transcription factor activity
G3W92_RS26380	COG0179	Fumarylacetoacetate (FAA) hydrolase
G3W92_RS26385	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
G3W92_RS26420	COG0284	orotidine-5'-phosphate decarboxylase activity
G3W92_RS26440	COG2027	D-alanyl-D-alanine carboxypeptidase
G3W92_RS26450	COG0009	L-threonylcarbamoyladenylate synthase
G3W92_RS26455	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
G3W92_RS26460	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
G3W92_RS26465	COG3118	belongs to the thioredoxin family
G3W92_RS26475	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
G3W92_RS26490	COG0469	pyruvate kinase activity
G3W92_RS26495	COG0126	phosphoglycerate kinase activity
G3W92_RS26510	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
G3W92_RS26520	COG0242	peptide deformylase activity
G3W92_RS26530	COG0758	DNA mediated transformation
G3W92_RS26535	COG2922	Belongs to the Smg family
G3W92_RS26545	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G3W92_RS26550	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G3W92_RS26555	COG1862	Preprotein translocase
G3W92_RS26560	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
G3W92_RS26570	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G3W92_RS26595	COG0318	PFAM AMP-dependent synthetase and ligase
G3W92_RS26605	COG1960	acyl-CoA dehydrogenase activity
G3W92_RS26615	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G3W92_RS26630	COG1024	Enoyl-CoA hydratase
G3W92_RS26630	COG1250	3-hydroxyacyl-CoA dehydrogenase
G3W92_RS26640	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W92_RS26655	COG1024	Enoyl-CoA hydratase
G3W92_RS26660	COG2197	response regulator
G3W92_RS26670	COG4948	Mandelate Racemase Muconate Lactonizing
G3W92_RS26675	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G3W92_RS26700	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G3W92_RS26710	COG0183	Belongs to the thiolase family
G3W92_RS26715	COG2030	dehydratase
G3W92_RS26720	COG1024	Enoyl-CoA hydratase
G3W92_RS26725	COG1250	3-hydroxyacyl-CoA dehydrogenase
G3W92_RS26725	COG1024	Enoyl-CoA hydratase
G3W92_RS26730	COG1024	Enoyl-CoA hydratase
G3W92_RS26735	COG1960	acyl-CoA dehydrogenase activity
G3W92_RS26740	COG2368	4-hydroxyphenylacetate
G3W92_RS26800	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS26810	COG1522	sequence-specific DNA binding
G3W92_RS26815	COG0625	glutathione transferase activity
G3W92_RS26830	COG5002	protein histidine kinase activity
G3W92_RS26830	COG5001	Diguanylate cyclase
G3W92_RS26855	COG0586	Pfam SNARE associated Golgi protein
G3W92_RS26875	COG3622	Belongs to the hyi family
G3W92_RS26880	COG3395	kinase activity
G3W92_RS26885	COG2084	Dehydrogenase
G3W92_RS26895	COG1522	sequence-specific DNA binding
G3W92_RS26915	COG4566	intracellular signal transduction
G3W92_RS26935	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
G3W92_RS26955	COG0625	glutathione transferase activity
G3W92_RS26980	COG0861	Integral membrane protein TerC family
G3W92_RS26990	COG1950	PFAM Membrane protein of
G3W92_RS27000	COG4783	chaperone-mediated protein folding
G3W92_RS27005	COG0315	cyclic pyranopterin monophosphate synthase activity
G3W92_RS27050	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G3W92_RS27060	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
G3W92_RS27090	COG3307	-O-antigen
G3W92_RS27095	COG4969	Belongs to the N-Me-Phe pilin family
G3W92_RS27115	COG0861	Integral membrane protein TerC family
G3W92_RS27120	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
G3W92_RS27125	COG0045	succinate-CoA ligase (ADP-forming) activity
G3W92_RS27130	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
G3W92_RS27135	COG2137	regulation of response to DNA damage stimulus
G3W92_RS27140	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
G3W92_RS27155	COG0642	Histidine kinase
G3W92_RS27165	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
G3W92_RS27165	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
G3W92_RS27175	COG0551	DNA topoisomerase type I activity
G3W92_RS27175	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
G3W92_RS27180	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
G3W92_RS27190	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G3W92_RS27200	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
G3W92_RS27205	COG0513	Belongs to the DEAD box helicase family
G3W92_RS27225	COG1473	amidohydrolase
G3W92_RS27240	COG0129	dihydroxy-acid dehydratase activity
G3W92_RS27245	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G3W92_RS27255	COG3842	ATPase activity
G3W92_RS27270	COG3833	ABC-type maltose transport systems, permease component
G3W92_RS27275	COG2982	Protein involved in outer membrane biogenesis
G3W92_RS27285	COG1047	Peptidyl-prolyl cis-trans
G3W92_RS27295	COG0765	amino acid transport
G3W92_RS27300	COG0765	amino acid transport
G3W92_RS27355	COG2814	Major facilitator Superfamily
G3W92_RS27360	COG0583	DNA-binding transcription factor activity
G3W92_RS27365	COG0165	Argininosuccinate lyase
G3W92_RS27385	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G3W92_RS27390	COG0667	Aldo Keto reductase
G3W92_RS27400	COG1522	sequence-specific DNA binding
G3W92_RS27405	COG2423	ornithine cyclodeaminase activity
G3W92_RS27415	COG2094	Belongs to the DNA glycosylase MPG family
G3W92_RS27465	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
G3W92_RS27495	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
G3W92_RS27500	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
G3W92_RS27505	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
G3W92_RS27520	COG0006	proline dipeptidase activity
G3W92_RS27535	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
G3W92_RS27555	COG0281	malic enzyme
G3W92_RS27555	COG0280	phosphate acetyltransferase
G3W92_RS27575	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
G3W92_RS27580	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G3W92_RS27585	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
G3W92_RS27595	COG1385	rRNA (uridine-N3-)-methyltransferase activity
G3W92_RS27605	COG3753	Protein conserved in bacteria
G3W92_RS27610	COG2814	Major facilitator Superfamily
G3W92_RS27615	COG2267	carboxylic ester hydrolase activity
G3W92_RS27635	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G3W92_RS27640	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G3W92_RS27645	COG0724	RNA recognition motif
G3W92_RS27650	COG0300	oxidoreductase activity
G3W92_RS27660	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
G3W92_RS27680	COG2066	Belongs to the glutaminase family
G3W92_RS27680	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
G3W92_RS27685	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
G3W92_RS27690	COG0706	membrane insertase activity
G3W92_RS27695	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
G3W92_RS27700	COG0594	ribonuclease P activity
G3W92_RS27705	COG0230	Belongs to the bacterial ribosomal protein bL34 family
G3W92_RS27710	COG1192	Involved in chromosome partitioning
G3W92_RS27725	COG1199	ATP-dependent helicase activity
G3W92_RS27890	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
G3W92_RS27945	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
G3W92_RS27970	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
G3W92_RS27975	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
G3W92_RS28015	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
G3W92_RS28020	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
G3W92_RS28290	COG4682	membrane
G3W92_RS28295	COG0433	COG0433 Predicted ATPase
G3W92_RS28395	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
G3W92_RS28395	COG0551	DNA topoisomerase type I activity
G3W92_RS28450	COG4974	Belongs to the 'phage' integrase family
G3W92_RS28625	COG0545	Peptidyl-prolyl cis-trans isomerase
G3W92_RS28635	COG2954	triphosphatase activity
G3W92_RS28715	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
G3W92_RS28750	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
G3W92_RS28810	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
G3W92_RS28825	COG3011	Protein conserved in bacteria
G3W92_RS28925	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
G3W92_RS29040	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
G3W92_RS29050	COG0215	cysteine-tRNA ligase activity
G3W92_RS29275	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G3W92_RS29360	COG1074	ATP-dependent DNA helicase activity
G3W92_RS29390	COG4286	Uncharacterised protein family (UPF0160)
G3W92_RS29405	COG2433	Pfam Transposase IS66
G3W92_RS29425	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G3W92_RS29425	COG0519	Catalyzes the synthesis of GMP from XMP
G3W92_RS29485	COG3181	Tripartite tricarboxylate transporter family receptor
G3W92_RS29520	COG1454	alcohol dehydrogenase
G3W92_RS29535	COG3181	Tripartite tricarboxylate transporter family receptor
G3W92_RS29540	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G3W92_RS29580	COG1484	DNA-dependent DNA replication
G3W92_RS29605	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
G3W92_RS29800	COG4650	regulator
G3W92_RS29870	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
G3W92_RS29895	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
G3W92_RS30155	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
G3W92_RS30180	COG4637	Psort location Cytoplasmic, score
G3W92_RS30215	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
G3W92_RS30220	COG1518	maintenance of DNA repeat elements
G3W92_RS30225	COG1203	CRISPR-associated helicase, Cas3
G3W92_RS30235	COG0587	DNA-directed DNA polymerase activity
G3W92_RS30305	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
G3W92_RS30345	COG0084	hydrolase, TatD family'
G3W92_RS30620	COG2268	Band 7 protein
G3W92_RS30645	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G3W92_RS30675	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G3W92_RS30685	COG0628	permease
G3W92_RS30695	COG1129	ABC transporter
G3W92_RS30730	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
G3W92_RS30795	COG0675	Transposase, IS605 OrfB family
G3W92_RS30845	COG1222	aaa ATPase
G3W92_RS30850	COG1199	ATP-dependent helicase activity
G3W92_RS30900	COG0557	exoribonuclease II activity
G3W92_RS30995	COG0617	tRNA 3'-terminal CCA addition
G3W92_RS31005	COG1051	belongs to the nudix hydrolase family
G3W92_RS31005	COG1056	cytidyltransferase-related domain
G3W92_RS31025	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
G3W92_RS31025	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G3W92_RS31065	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
G3W92_RS31135	COG2189	Belongs to the N(4) N(6)-methyltransferase family
G3W92_RS31180	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G3W92_RS31185	COG1484	DNA-dependent DNA replication
G3W92_RS31205	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
G3W92_RS31235	COG0494	nUDIX hydrolase
G3W92_RS31315	COG4974	Belongs to the 'phage' integrase family
G3W92_RS31465	COG0328	RNA-DNA hybrid ribonuclease activity
G3W92_RS31515	COG0629	single-stranded DNA binding
G3W92_RS31550	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
G3W92_RS31585	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G3W92_RS31585	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G3W92_RS31720	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
G3W92_RS31725	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
G3W92_RS31770	COG0840	transmembrane signaling receptor activity
G3W92_RS31775	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
G3W92_RS31840	COG0582	viral genome integration into host DNA
G3W92_RS31965	COG0210	DNA helicase
G3W92_RS32010	COG0653	protein targeting
G3W92_RS32045	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
G3W92_RS32055	COG1484	DNA-dependent DNA replication
G3W92_RS32065	COG0187	DNA topoisomerase II activity
G3W92_RS32070	COG0739	heme binding
G3W92_RS32070	COG1196	nuclear chromosome segregation
G3W92_RS32070	COG0741	lytic transglycosylase activity
G3W92_RS32075	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
G3W92_RS32105	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
G3W92_RS32125	COG1192	Involved in chromosome partitioning
G3W92_RS32185	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
G3W92_RS32195	COG2301	Belongs to the HpcH HpaI aldolase family
G3W92_RS32205	COG1301	dicarboxylic acid transport
G3W92_RS32210	COG0583	DNA-binding transcription factor activity
G3W92_RS32220	COG2828	Protein conserved in bacteria
G3W92_RS32265	COG1473	amidohydrolase
G3W92_RS32270	COG0129	dihydroxy-acid dehydratase activity
G3W92_RS32275	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G3W92_RS32295	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
G3W92_RS32310	COG1522	sequence-specific DNA binding
G3W92_RS32315	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
G3W92_RS32335	COG0735	belongs to the Fur family
G3W92_RS32345	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G3W92_RS32360	COG1522	sequence-specific DNA binding
G3W92_RS32365	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
G3W92_RS32390	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G3W92_RS32395	COG4166	transmembrane transport
G3W92_RS32400	COG0601	transmembrane transport
G3W92_RS32405	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G3W92_RS32415	COG0473	3-isopropylmalate dehydrogenase activity
G3W92_RS32420	COG1012	belongs to the aldehyde dehydrogenase family
G3W92_RS32425	COG1252	NADH dehydrogenase
G3W92_RS32435	COG0196	riboflavin kinase activity
G3W92_RS32445	COG1960	acyl-CoA dehydrogenase activity
G3W92_RS32470	COG3485	protocatechuate 3,4-dioxygenase
G3W92_RS32480	COG2814	Major facilitator Superfamily
G3W92_RS32515	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS32525	COG0583	DNA-binding transcription factor activity
G3W92_RS32540	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS32550	COG0492	ferredoxin-NADP+ reductase activity
G3W92_RS32565	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
G3W92_RS32570	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
G3W92_RS32595	COG0583	DNA-binding transcription factor activity
G3W92_RS32605	COG1012	belongs to the aldehyde dehydrogenase family
G3W92_RS32625	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS32635	COG0559	Belongs to the binding-protein-dependent transport system permease family
G3W92_RS32660	COG1024	Enoyl-CoA hydratase
G3W92_RS32665	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G3W92_RS32675	COG3386	PFAM SMP-30 Gluconolaconase
G3W92_RS32685	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W92_RS32690	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W92_RS32695	COG1024	Enoyl-CoA hydratase
G3W92_RS32705	COG0667	Aldo Keto reductase
G3W92_RS32735	COG2188	Transcriptional regulator
G3W92_RS32740	COG1454	alcohol dehydrogenase
G3W92_RS32765	COG0667	Aldo Keto reductase
G3W92_RS32770	COG0667	Aldo Keto reductase
G3W92_RS32780	COG0667	Aldo Keto reductase
G3W92_RS32825	COG0589	response to stress
G3W92_RS32845	COG0583	DNA-binding transcription factor activity
G3W92_RS32875	COG2337	Toxic component of a toxin-antitoxin (TA) module
G3W92_RS32885	COG0587	DNA-directed DNA polymerase activity
G3W92_RS32935	COG3328	transposase activity
G3W92_RS32965	COG0583	DNA-binding transcription factor activity
G3W92_RS33085	COG1022	Amp-dependent synthetase and ligase
G3W92_RS33105	COG0559	Belongs to the binding-protein-dependent transport system permease family
G3W92_RS33135	COG0318	PFAM AMP-dependent synthetase and ligase
G3W92_RS33140	COG1309	transcriptional regulator
G3W92_RS33150	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W92_RS33165	COG1250	3-hydroxyacyl-CoA dehydrogenase
G3W92_RS33170	COG1024	Enoyl-CoA hydratase
G3W92_RS33175	COG1024	Enoyl-CoA hydratase
G3W92_RS33180	COG0183	Belongs to the thiolase family
G3W92_RS33185	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G3W92_RS33195	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS33210	COG4638	Rieske (2fe-2S)
G3W92_RS33280	COG0028	Belongs to the TPP enzyme family
G3W92_RS33290	COG4638	Rieske (2fe-2S)
G3W92_RS33300	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS33305	COG2175	clavaminate synthase activity
G3W92_RS33310	COG0028	Belongs to the TPP enzyme family
G3W92_RS33325	COG3347	Dehydrogenase
G3W92_RS33325	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS33340	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W92_RS33345	COG1960	acyl-CoA dehydrogenase activity
G3W92_RS33360	COG0028	Belongs to the TPP enzyme family
G3W92_RS33375	COG0318	PFAM AMP-dependent synthetase and ligase
G3W92_RS33380	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W92_RS33405	COG0583	DNA-binding transcription factor activity
G3W92_RS33425	COG0183	Belongs to the thiolase family
G3W92_RS33440	COG1024	Enoyl-CoA hydratase
G3W92_RS33445	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W92_RS33455	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G3W92_RS33460	COG2079	MmgE PrpD family protein
G3W92_RS33465	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS33470	COG1609	Transcriptional regulator
G3W92_RS33560	COG1234	tRNA 3'-trailer cleavage
G3W92_RS33585	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G3W92_RS33590	COG2159	amidohydrolase
G3W92_RS33595	COG3618	amidohydrolase
G3W92_RS33640	COG1960	acyl-CoA dehydrogenase activity
G3W92_RS33660	COG1024	Enoyl-CoA hydratase
G3W92_RS33670	COG1902	pentaerythritol trinitrate reductase activity
G3W92_RS33675	COG1024	Enoyl-CoA hydratase
G3W92_RS33680	COG1960	acyl-CoA dehydrogenase activity
G3W92_RS33690	COG1024	Enoyl-CoA hydratase
G3W92_RS33695	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W92_RS33700	COG1960	acyl-CoA dehydrogenase activity
G3W92_RS33705	COG1960	acyl-CoA dehydrogenase activity
G3W92_RS33710	COG1024	Enoyl-CoA hydratase
G3W92_RS33715	COG0318	PFAM AMP-dependent synthetase and ligase
G3W92_RS33735	COG1042	CoA-binding domain protein
G3W92_RS33735	COG0045	succinate-CoA ligase (ADP-forming) activity
G3W92_RS33735	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G3W92_RS33740	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS33745	COG1024	Enoyl-CoA hydratase
G3W92_RS33750	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G3W92_RS33750	COG0045	succinate-CoA ligase (ADP-forming) activity
G3W92_RS33750	COG1042	CoA-binding domain protein
G3W92_RS33760	COG1960	acyl-CoA dehydrogenase activity
G3W92_RS33765	COG1960	acyl-CoA dehydrogenase activity
G3W92_RS33770	COG1024	Enoyl-CoA hydratase
G3W92_RS33775	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS33780	COG2030	dehydratase
G3W92_RS33790	COG0583	DNA-binding transcription factor activity
G3W92_RS33795	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS33800	COG2070	2-Nitropropane dioxygenase
G3W92_RS33805	COG2130	NADP-dependent
G3W92_RS33815	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS33825	COG4453	Protein conserved in bacteria
G3W92_RS33860	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
G3W92_RS33875	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
G3W92_RS33925	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G3W92_RS33930	COG5383	Protein conserved in bacteria
G3W92_RS33935	COG0525	valine-tRNA ligase activity
G3W92_RS33940	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
G3W92_RS33945	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
G3W92_RS33950	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G3W92_RS33970	COG0559	Belongs to the binding-protein-dependent transport system permease family
G3W92_RS33980	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
G3W92_RS33985	COG0277	FAD linked oxidase domain protein
G3W92_RS33990	COG0028	Belongs to the TPP enzyme family
G3W92_RS34005	COG5642	Protein of unknown function (DUF2384)
G3W92_RS34015	COG0784	Response regulator, receiver
G3W92_RS34015	COG4191	Histidine kinase
G3W92_RS34040	COG0604	alcohol dehydrogenase
G3W92_RS34060	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
G3W92_RS34065	COG0800	Aldolase
G3W92_RS34080	COG1012	belongs to the aldehyde dehydrogenase family
G3W92_RS34120	COG0642	Histidine kinase
G3W92_RS34150	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G3W92_RS34160	COG4638	Rieske (2fe-2S)
G3W92_RS34165	COG2267	carboxylic ester hydrolase activity
G3W92_RS34185	COG2309	aminopeptidase activity
G3W92_RS34195	COG1335	isochorismatase
G3W92_RS34200	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G3W92_RS34230	COG1414	Transcriptional regulator
G3W92_RS34235	COG4372	Transposase
G3W92_RS34270	COG4372	Transposase
G3W92_RS34290	COG0596	Alpha beta hydrolase
G3W92_RS34335	COG2309	aminopeptidase activity
G3W92_RS34340	COG1335	isochorismatase
G3W92_RS34370	COG2223	nitrite transmembrane transporter activity
G3W92_RS34400	COG1024	Enoyl-CoA hydratase
G3W92_RS34415	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS34420	COG0183	Belongs to the thiolase family
G3W92_RS34480	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
G3W92_RS34500	COG2184	nucleotidyltransferase activity
G3W92_RS34605	COG1063	alcohol dehydrogenase
G3W92_RS34610	COG4948	Mandelate Racemase Muconate Lactonizing
G3W92_RS34615	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
G3W92_RS34620	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G3W92_RS34625	COG0246	Mannitol dehydrogenase
G3W92_RS34635	COG1024	Enoyl-CoA hydratase
G3W92_RS34655	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W92_RS34680	COG0583	DNA-binding transcription factor activity
G3W92_RS34700	COG3300	MHYT domain
G3W92_RS34700	COG5001	Diguanylate cyclase
G3W92_RS34780	COG3846	protein secretion by the type IV secretion system
G3W92_RS34805	COG3504	Conjugal transfer protein
G3W92_RS34815	COG3451	type IV secretory pathway VirB4
G3W92_RS34820	COG5268	conjugation
G3W92_RS34825	COG3838	Conjugal transfer protein Trbc
G3W92_RS34830	COG4962	Type ii secretion system protein e
G3W92_RS34880	COG1199	ATP-dependent helicase activity
G3W92_RS34925	COG1192	Involved in chromosome partitioning
G3W92_RS34940	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
G3W92_RS34955	COG1960	acyl-CoA dehydrogenase activity
G3W92_RS34965	COG2030	dehydratase
G3W92_RS34970	COG0183	Belongs to the thiolase family
G3W92_RS34985	COG1960	acyl-CoA dehydrogenase activity
G3W92_RS34990	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
G3W92_RS34995	COG0425	Belongs to the sulfur carrier protein TusA family
G3W92_RS34995	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G3W92_RS35005	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS35020	COG3181	Tripartite tricarboxylate transporter family receptor
G3W92_RS35035	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
G3W92_RS35065	COG0583	DNA-binding transcription factor activity
G3W92_RS35085	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
G3W92_RS35090	COG0583	DNA-binding transcription factor activity
G3W92_RS35135	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS35135	COG3321	synthase
G3W92_RS35135	COG0604	alcohol dehydrogenase
G3W92_RS35145	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
G3W92_RS35170	COG3119	arylsulfatase activity
G3W92_RS35185	COG0583	DNA-binding transcription factor activity
G3W92_RS35195	COG3181	Tripartite tricarboxylate transporter family receptor
G3W92_RS35205	COG2084	Dehydrogenase
G3W92_RS35240	COG1309	transcriptional regulator
G3W92_RS35245	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
G3W92_RS35260	COG1024	Enoyl-CoA hydratase
G3W92_RS35280	COG0318	PFAM AMP-dependent synthetase and ligase
G3W92_RS35285	COG1960	acyl-CoA dehydrogenase activity
G3W92_RS35320	COG2072	flavoprotein involved in K transport
G3W92_RS35365	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS35380	COG4566	intracellular signal transduction
G3W92_RS35395	COG2831	hemolysin activation secretion protein
G3W92_RS35420	COG3181	Tripartite tricarboxylate transporter family receptor
G3W92_RS35430	COG4948	Mandelate Racemase Muconate Lactonizing
G3W92_RS35450	COG3842	ATPase activity
G3W92_RS35475	COG3386	PFAM SMP-30 Gluconolaconase
G3W92_RS35495	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
G3W92_RS35505	COG2197	response regulator
G3W92_RS35510	COG4585	Histidine kinase
G3W92_RS35515	COG2202	Pas domain
G3W92_RS35515	COG2205	protein histidine kinase activity
G3W92_RS35520	COG0667	Aldo Keto reductase
G3W92_RS35530	COG0765	amino acid transport
G3W92_RS35535	COG0765	amino acid transport
G3W92_RS35540	COG1126	abc transporter atp-binding protein
G3W92_RS35550	COG1522	sequence-specific DNA binding
G3W92_RS35570	COG3268	Saccharopine dehydrogenase
G3W92_RS35575	COG0318	PFAM AMP-dependent synthetase and ligase
G3W92_RS35595	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W92_RS35605	COG0154	amidase activity
G3W92_RS35615	COG2301	Belongs to the HpcH HpaI aldolase family
G3W92_RS35620	COG0183	Belongs to the thiolase family
G3W92_RS35625	COG0604	alcohol dehydrogenase
G3W92_RS35650	COG1024	Enoyl-CoA hydratase
G3W92_RS35655	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W92_RS35660	COG2814	Major facilitator Superfamily
G3W92_RS35670	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
G3W92_RS35680	COG0583	DNA-binding transcription factor activity
G3W92_RS35685	COG3210	domain, Protein
G3W92_RS35725	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS35735	COG3181	Tripartite tricarboxylate transporter family receptor
G3W92_RS35740	COG1053	succinate dehydrogenase
G3W92_RS35755	COG3181	Tripartite tricarboxylate transporter family receptor
G3W92_RS35765	COG0165	Argininosuccinate lyase
G3W92_RS35770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G3W92_RS35780	COG0765	amino acid transport
G3W92_RS35785	COG0010	Belongs to the arginase family
G3W92_RS35795	COG0579	oxidoreductase
G3W92_RS35815	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G3W92_RS35820	COG1473	amidohydrolase
G3W92_RS35825	COG0251	oxidation-reduction process
G3W92_RS35835	COG1116	anion transmembrane transporter activity
G3W92_RS35840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G3W92_RS35845	COG0154	amidase activity
G3W92_RS35855	COG0156	8-amino-7-oxononanoate synthase activity
G3W92_RS35870	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G3W92_RS35890	COG1335	isochorismatase
G3W92_RS35910	COG0791	NLP P60 protein
G3W92_RS35920	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
G3W92_RS35950	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G3W92_RS35955	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G3W92_RS35980	COG3386	PFAM SMP-30 Gluconolaconase
G3W92_RS35985	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
G3W92_RS35995	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G3W92_RS36005	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W92_RS36030	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W92_RS36040	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
G3W92_RS36045	COG0439	Biotin carboxylase
G3W92_RS36055	COG3181	Tripartite tricarboxylate transporter family receptor
G3W92_RS36080	COG3181	Tripartite tricarboxylate transporter family receptor
G3W92_RS36105	COG1172	Belongs to the binding-protein-dependent transport system permease family
G3W92_RS36120	COG0066	3-isopropylmalate dehydratase activity
G3W92_RS36125	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
G3W92_RS36130	COG0277	FAD linked oxidase domain protein
G3W92_RS36150	COG0028	Belongs to the TPP enzyme family
G3W92_RS36180	COG1126	abc transporter atp-binding protein
G3W92_RS36190	COG0765	amino acid transport
G3W92_RS36205	COG0583	DNA-binding transcription factor activity
G3W92_RS36215	COG0625	glutathione transferase activity
G3W92_RS36255	COG3181	Tripartite tricarboxylate transporter family receptor
G3W92_RS36260	COG0583	DNA-binding transcription factor activity
G3W92_RS36265	COG0604	alcohol dehydrogenase
G3W92_RS36275	COG1024	Enoyl-CoA hydratase
G3W92_RS36285	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3W92_RS36325	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
G3W92_RS36330	COG1414	Transcriptional regulator
G3W92_RS36350	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G3W92_RS36355	COG0586	Pfam SNARE associated Golgi protein
G3W92_RS36365	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
G3W92_RS36365	COG1672	PFAM Archaeal ATPase
G3W92_RS36385	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS36390	COG1028	Short-chain dehydrogenase reductase Sdr
G3W92_RS36405	COG1176	ABC-type spermidine putrescine transport system, permease component I
G3W92_RS36410	COG3842	ATPase activity
G3W92_RS36415	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
G3W92_RS36435	COG0439	Biotin carboxylase
G3W92_RS36440	COG0511	ligase activity, forming carbon-carbon bonds
G3W92_RS36450	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G3W92_RS36455	COG2721	sulfolactate sulfo-lyase activity
G3W92_RS36470	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
G3W92_RS36475	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G3W92_RS36480	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3W92_RS36500	COG0445	tRNA wobble uridine modification
G3W92_RS36505	COG3181	Tripartite tricarboxylate transporter family receptor
G3W92_RS36515	COG1960	acyl-CoA dehydrogenase activity
G3W92_RS36535	COG0318	PFAM AMP-dependent synthetase and ligase
G3W92_RS36540	COG1414	Transcriptional regulator
G3W92_RS36575	COG1053	succinate dehydrogenase
G3W92_RS36580	COG2079	MmgE PrpD family protein
G3W92_RS36585	COG0523	cobalamin synthesis protein
G3W92_RS36595	COG1335	isochorismatase
G3W92_RS36605	COG3550	peptidyl-serine autophosphorylation
G3W92_RS36610	COG1760	l-serine dehydratase
G3W92_RS36620	COG1335	isochorismatase
G3W92_RS36635	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G3W92_RS36640	COG4569	acetaldehyde dehydrogenase (acetylating) activity
G3W92_RS36715	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
G3W92_RS36715	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
G3W92_RS36790	COG2207	Transcriptional regulator
G3W92_RS36795	COG0789	Transcriptional regulator
G3W92_RS36840	COG3181	Tripartite tricarboxylate transporter family receptor
G3W92_RS36845	COG0235	Class ii aldolase
G3W92_RS36850	COG1024	Enoyl-CoA hydratase
G3W92_RS36860	COG3119	arylsulfatase activity
G3W92_RS36905	COG1917	Cupin 2, conserved barrel domain protein
G3W92_RS36915	COG3181	Tripartite tricarboxylate transporter family receptor
G3W92_RS36925	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G3W92_RS36930	COG4569	acetaldehyde dehydrogenase (acetylating) activity
G3W92_RS37000	COG0583	DNA-binding transcription factor activity
G3W92_RS37005	COG0583	DNA-binding transcription factor activity
G3W92_RS37020	COG3181	Tripartite tricarboxylate transporter family receptor
G3W92_RS37025	COG2814	Major facilitator Superfamily
G3W92_RS37040	COG3639	organic phosphonate transmembrane transporter activity
G3W92_RS37045	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
G3W92_RS37050	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
G3W92_RS37055	COG3454	Phosphonate metabolism
G3W92_RS37060	COG4778	phosphonate C-P lyase system protein PhnL
G3W92_RS37065	COG4107	phosphonate C-P lyase system protein PhnK
G3W92_RS37070	COG3627	carbon phosphorus lyase activity
G3W92_RS37075	COG3626	phosphonate metabolism
G3W92_RS37085	COG3624	Phosphonate C-P lyase system protein PhnG
G3W92_RS37090	COG1609	Transcriptional regulator
G3W92_RS37095	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
G3W92_RS37100	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
G3W92_RS37110	COG0318	PFAM AMP-dependent synthetase and ligase
G3W92_RS37125	COG1024	Enoyl-CoA hydratase
G3W92_RS37150	COG0183	Belongs to the thiolase family
G3W92_RS37165	COG1024	Enoyl-CoA hydratase
G3W92_RS37170	COG0318	PFAM AMP-dependent synthetase and ligase
G3W92_RS37185	COG4566	intracellular signal transduction
G3W92_RS37210	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G3W92_RS37225	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G3W92_RS37240	COG2175	clavaminate synthase activity
G3W92_RS37340	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
G3W92_RS37360	COG1121	(ABC) transporter
G3W92_RS37440	COG3701	Conjugal transfer protein
G3W92_RS37445	COG3451	type IV secretory pathway VirB4
G3W92_RS37450	COG5268	conjugation
G3W92_RS37455	COG3838	Conjugal transfer protein Trbc
G3W92_RS37460	COG4962	Type ii secretion system protein e
G3W92_RS37550	COG4584	PFAM Integrase catalytic
G3W92_RS37555	COG1484	DNA-dependent DNA replication