L21SP4_RS12115 392d65e5e52f30388d126c5fd186d8dd 1113 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 900 966 4.4E-18 T 22-04-2016 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 L21SP4_RS12115 392d65e5e52f30388d126c5fd186d8dd 1113 SUPERFAMILY SSF53901 820 1107 4.81E-45 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 L21SP4_RS12115 392d65e5e52f30388d126c5fd186d8dd 1113 Gene3D G3DSA:3.40.47.10 792 954 6.8E-39 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 L21SP4_RS12115 392d65e5e52f30388d126c5fd186d8dd 1113 PANTHER PTHR11624:SF21 321 668 1.1E-119 T 22-04-2016 L21SP4_RS12115 392d65e5e52f30388d126c5fd186d8dd 1113 PANTHER PTHR11624:SF21 5 290 1.1E-119 T 22-04-2016 L21SP4_RS12115 392d65e5e52f30388d126c5fd186d8dd 1113 Pfam PF00676 Dehydrogenase E1 component 17 307 6.5E-41 T 22-04-2016 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 L21SP4_RS12115 392d65e5e52f30388d126c5fd186d8dd 1113 PANTHER PTHR11624 321 668 1.1E-119 T 22-04-2016 IPR033247 Transketolase family L21SP4_RS12115 392d65e5e52f30388d126c5fd186d8dd 1113 PANTHER PTHR11624 5 290 1.1E-119 T 22-04-2016 IPR033247 Transketolase family L21SP4_RS12115 392d65e5e52f30388d126c5fd186d8dd 1113 SUPERFAMILY SSF52518 333 538 7.43E-47 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold L21SP4_RS12115 392d65e5e52f30388d126c5fd186d8dd 1113 SUPERFAMILY SSF52922 524 656 1.06E-29 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 L21SP4_RS12115 392d65e5e52f30388d126c5fd186d8dd 1113 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 1021 1107 5.7E-22 T 22-04-2016 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 L21SP4_RS12115 392d65e5e52f30388d126c5fd186d8dd 1113 Gene3D G3DSA:3.40.47.10 955 1107 1.4E-36 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 L21SP4_RS12115 392d65e5e52f30388d126c5fd186d8dd 1113 Gene3D G3DSA:2.40.50.100 681 757 9.5E-19 T 22-04-2016 L21SP4_RS12115 392d65e5e52f30388d126c5fd186d8dd 1113 Pfam PF00364 Biotin-requiring enzyme 686 746 2.8E-16 T 22-04-2016 IPR000089 Biotin/lipoyl attachment L21SP4_RS12115 392d65e5e52f30388d126c5fd186d8dd 1113 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 697 726 - T 22-04-2016 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site L21SP4_RS12115 392d65e5e52f30388d126c5fd186d8dd 1113 Gene3D G3DSA:3.40.50.970 2 347 1.9E-77 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold L21SP4_RS12115 392d65e5e52f30388d126c5fd186d8dd 1113 Pfam PF02780 Transketolase, C-terminal domain 528 640 1.3E-28 T 22-04-2016 IPR033248 Transketolase, C-terminal domain L21SP4_RS12115 392d65e5e52f30388d126c5fd186d8dd 1113 Gene3D G3DSA:3.40.50.920 529 653 4.6E-31 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 L21SP4_RS12115 392d65e5e52f30388d126c5fd186d8dd 1113 Pfam PF02779 Transketolase, pyrimidine binding domain 334 510 1.5E-24 T 22-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain L21SP4_RS12115 392d65e5e52f30388d126c5fd186d8dd 1113 Gene3D G3DSA:3.40.50.970 348 528 1.9E-49 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold L21SP4_RS12115 392d65e5e52f30388d126c5fd186d8dd 1113 SUPERFAMILY SSF52518 4 307 1.75E-60 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold L21SP4_RS12115 392d65e5e52f30388d126c5fd186d8dd 1113 SMART SM00861 335 511 8.5E-38 T 22-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain L21SP4_RS12115 392d65e5e52f30388d126c5fd186d8dd 1113 SUPERFAMILY SSF51230 681 757 8.38E-18 T 22-04-2016 IPR011053 Single hybrid motif L21SP4_RS00920 3c2252d173d6ccb18e83f71c4bb2e835 329 SUPERFAMILY SSF117892 62 145 3.79E-19 T 22-04-2016 IPR001107 Band 7 domain L21SP4_RS00920 3c2252d173d6ccb18e83f71c4bb2e835 329 SUPERFAMILY SSF117892 177 227 3.79E-19 T 22-04-2016 IPR001107 Band 7 domain L21SP4_RS00920 3c2252d173d6ccb18e83f71c4bb2e835 329 SMART SM00244 28 217 4.7E-24 T 22-04-2016 IPR001107 Band 7 domain L21SP4_RS00920 3c2252d173d6ccb18e83f71c4bb2e835 329 PIRSF PIRSF005651 2 329 1.1E-95 T 22-04-2016 IPR010200 HflC GO:0016021|GO:0052547 L21SP4_RS00920 3c2252d173d6ccb18e83f71c4bb2e835 329 PANTHER PTHR10264:SF80 10 146 1.8E-64 T 22-04-2016 L21SP4_RS00920 3c2252d173d6ccb18e83f71c4bb2e835 329 PANTHER PTHR10264:SF80 178 321 1.8E-64 T 22-04-2016 L21SP4_RS00920 3c2252d173d6ccb18e83f71c4bb2e835 329 TIGRFAM TIGR01932 hflC: HflC protein 14 320 5.2E-80 T 22-04-2016 IPR010200 HflC GO:0016021|GO:0052547 L21SP4_RS00920 3c2252d173d6ccb18e83f71c4bb2e835 329 Pfam PF01145 SPFH domain / Band 7 family 32 237 1.2E-21 T 22-04-2016 IPR001107 Band 7 domain L21SP4_RS00920 3c2252d173d6ccb18e83f71c4bb2e835 329 PANTHER PTHR10264 10 146 1.8E-64 T 22-04-2016 IPR001972 Stomatin family GO:0016020 L21SP4_RS00920 3c2252d173d6ccb18e83f71c4bb2e835 329 PANTHER PTHR10264 178 321 1.8E-64 T 22-04-2016 IPR001972 Stomatin family GO:0016020 L21SP4_RS11795 cc68479c4a9ad2d801a63395be72a494 312 PANTHER PTHR37419 35 230 5.2E-14 T 22-04-2016 L21SP4_RS11795 cc68479c4a9ad2d801a63395be72a494 312 Pfam PF07804 HipA-like C-terminal domain 140 279 7.9E-28 T 22-04-2016 IPR012893 HipA-like, C-terminal L21SP4_RS11795 cc68479c4a9ad2d801a63395be72a494 312 Pfam PF07805 HipA-like N-terminal domain 54 134 6.1E-18 T 22-04-2016 IPR012894 HipA, N-terminal subdomain 2 L21SP4_RS09650 d0378a24d469b84c189d11039e062905 207 ProSitePatterns PS00018 EF-hand calcium-binding domain. 85 97 - T 22-04-2016 IPR018247 EF-Hand 1, calcium-binding site L21SP4_RS02815 6c9e0ea430225682b033f226330927fb 91 Gene3D G3DSA:1.10.10.10 4 89 2.8E-27 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS02815 6c9e0ea430225682b033f226330927fb 91 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 55 70 1.1E-14 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 L21SP4_RS02815 6c9e0ea430225682b033f226330927fb 91 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 40 55 1.1E-14 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 L21SP4_RS02815 6c9e0ea430225682b033f226330927fb 91 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 8 23 1.1E-14 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 L21SP4_RS02815 6c9e0ea430225682b033f226330927fb 91 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 27 38 1.1E-14 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 L21SP4_RS02815 6c9e0ea430225682b033f226330927fb 91 SUPERFAMILY SSF46785 4 82 4.46E-24 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS02815 6c9e0ea430225682b033f226330927fb 91 SMART SM00418 6 84 1.8E-20 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 L21SP4_RS02815 6c9e0ea430225682b033f226330927fb 91 PANTHER PTHR33154 1 71 7.5E-23 T 22-04-2016 L21SP4_RS02815 6c9e0ea430225682b033f226330927fb 91 Pfam PF12840 Helix-turn-helix domain 5 64 2.0E-15 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS01645 84eb490aec3584760d9941e0704049d1 249 Pfam PF02511 Thymidylate synthase complementing protein 4 205 1.2E-60 T 22-04-2016 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 L21SP4_RS01645 84eb490aec3584760d9941e0704049d1 249 PANTHER PTHR34934 1 242 5.8E-57 T 22-04-2016 L21SP4_RS01645 84eb490aec3584760d9941e0704049d1 249 TIGRFAM TIGR02170 thyX: thymidylate synthase, flavin-dependent 3 209 1.4E-55 T 22-04-2016 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 L21SP4_RS01645 84eb490aec3584760d9941e0704049d1 249 SUPERFAMILY SSF69796 3 216 5.36E-59 T 22-04-2016 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 L21SP4_RS01645 84eb490aec3584760d9941e0704049d1 249 Hamap MF_01408 Thymidylate synthase ThyX [thyX]. 1 219 28.888 T 22-04-2016 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 L21SP4_RS01705 447d1c3b5bdffa17cc25cd718b8b8565 148 Gene3D G3DSA:3.40.930.10 1 147 2.6E-41 T 22-04-2016 IPR002178 PTS EIIA type-2 domain KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- L21SP4_RS01705 447d1c3b5bdffa17cc25cd718b8b8565 148 PANTHER PTHR30505 1 146 7.4E-36 T 22-04-2016 L21SP4_RS01705 447d1c3b5bdffa17cc25cd718b8b8565 148 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 6 146 6.4E-34 T 22-04-2016 IPR002178 PTS EIIA type-2 domain KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- L21SP4_RS01705 447d1c3b5bdffa17cc25cd718b8b8565 148 SUPERFAMILY SSF55804 1 147 3.79E-35 T 22-04-2016 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: REACT_15518 L21SP4_RS01705 447d1c3b5bdffa17cc25cd718b8b8565 148 PANTHER PTHR30505:SF5 1 146 7.4E-36 T 22-04-2016 L21SP4_RS07935 b8401d3a83fd883a43f4783718a08e34 138 SUPERFAMILY SSF111038 2 137 2.09E-37 T 22-04-2016 IPR001602 Uncharacterised protein family UPF0047 L21SP4_RS07935 b8401d3a83fd883a43f4783718a08e34 138 PANTHER PTHR30615 2 138 1.2E-29 T 22-04-2016 L21SP4_RS07935 b8401d3a83fd883a43f4783718a08e34 138 ProSitePatterns PS01314 Uncharacterized protein family UPF0047 signature. 98 116 - T 22-04-2016 IPR001602 Uncharacterised protein family UPF0047 L21SP4_RS07935 b8401d3a83fd883a43f4783718a08e34 138 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 6 137 1.5E-27 T 22-04-2016 IPR001602 Uncharacterised protein family UPF0047 L21SP4_RS07935 b8401d3a83fd883a43f4783718a08e34 138 PIRSF PIRSF004681 1 137 1.4E-31 T 22-04-2016 IPR001602 Uncharacterised protein family UPF0047 L21SP4_RS07935 b8401d3a83fd883a43f4783718a08e34 138 Pfam PF01894 Uncharacterised protein family UPF0047 18 134 2.9E-29 T 22-04-2016 IPR001602 Uncharacterised protein family UPF0047 L21SP4_RS07935 b8401d3a83fd883a43f4783718a08e34 138 Gene3D G3DSA:2.60.120.460 1 136 3.4E-36 T 22-04-2016 IPR001602 Uncharacterised protein family UPF0047 L21SP4_RS10800 0eebc7b269e618e733786048b9855951 888 SUPERFAMILY SSF52518 478 696 4.0E-82 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold L21SP4_RS10800 0eebc7b269e618e733786048b9855951 888 PANTHER PTHR11624 362 449 0.0 T 22-04-2016 IPR033247 Transketolase family L21SP4_RS10800 0eebc7b269e618e733786048b9855951 888 PANTHER PTHR11624 478 533 0.0 T 22-04-2016 IPR033247 Transketolase family L21SP4_RS10800 0eebc7b269e618e733786048b9855951 888 PANTHER PTHR11624 787 870 0.0 T 22-04-2016 IPR033247 Transketolase family L21SP4_RS10800 0eebc7b269e618e733786048b9855951 888 PANTHER PTHR11624 551 766 0.0 T 22-04-2016 IPR033247 Transketolase family L21SP4_RS10800 0eebc7b269e618e733786048b9855951 888 PANTHER PTHR11624 73 293 0.0 T 22-04-2016 IPR033247 Transketolase family L21SP4_RS10800 0eebc7b269e618e733786048b9855951 888 Gene3D G3DSA:3.40.50.970 477 702 2.4E-100 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold L21SP4_RS10800 0eebc7b269e618e733786048b9855951 888 Gene3D G3DSA:3.40.50.970 56 466 2.9E-149 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold L21SP4_RS10800 0eebc7b269e618e733786048b9855951 888 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 103 297 3.7E-8 T 22-04-2016 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 L21SP4_RS10800 0eebc7b269e618e733786048b9855951 888 SUPERFAMILY SSF52518 56 467 5.89E-132 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold L21SP4_RS10800 0eebc7b269e618e733786048b9855951 888 PIRSF PIRSF000156 2 888 0.0 T 22-04-2016 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 L21SP4_RS10800 0eebc7b269e618e733786048b9855951 888 PANTHER PTHR11624:SF67 362 449 0.0 T 22-04-2016 L21SP4_RS10800 0eebc7b269e618e733786048b9855951 888 PANTHER PTHR11624:SF67 478 533 0.0 T 22-04-2016 L21SP4_RS10800 0eebc7b269e618e733786048b9855951 888 PANTHER PTHR11624:SF67 787 870 0.0 T 22-04-2016 L21SP4_RS10800 0eebc7b269e618e733786048b9855951 888 PANTHER PTHR11624:SF67 551 766 0.0 T 22-04-2016 L21SP4_RS10800 0eebc7b269e618e733786048b9855951 888 PANTHER PTHR11624:SF67 73 293 0.0 T 22-04-2016 L21SP4_RS10800 0eebc7b269e618e733786048b9855951 888 SUPERFAMILY SSF52922 699 886 1.57E-42 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 L21SP4_RS10800 0eebc7b269e618e733786048b9855951 888 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 10 886 0.0 T 22-04-2016 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 L21SP4_RS10800 0eebc7b269e618e733786048b9855951 888 Gene3D G3DSA:3.40.50.920 705 886 3.5E-55 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 L21SP4_RS01250 0380fb46332425bd88676de352c5fa34 226 Pfam PF06439 Domain of Unknown Function (DUF1080) 21 222 6.9E-40 T 22-04-2016 IPR010496 Domain of unknown function DUF1080 L21SP4_RS08140 5b703a94d14d188f5111a161463e960a 549 Pfam PF03063 Prismane/CO dehydrogenase family 1 545 1.5E-172 T 22-04-2016 IPR004137 Hydroxylamine reductase/Ni-containing CO dehydrogenase GO:0016491|GO:0055114 KEGG: 00910+1.7.99.1 L21SP4_RS08140 5b703a94d14d188f5111a161463e960a 549 PANTHER PTHR30109 1 548 1.5E-280 T 22-04-2016 L21SP4_RS08140 5b703a94d14d188f5111a161463e960a 549 Gene3D G3DSA:3.40.50.2030 380 547 9.3E-73 T 22-04-2016 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 L21SP4_RS08140 5b703a94d14d188f5111a161463e960a 549 SUPERFAMILY SSF56821 1 548 1.4E-193 T 22-04-2016 IPR011254 Prismane-like GO:0003824|GO:0016491|GO:0055114 L21SP4_RS08140 5b703a94d14d188f5111a161463e960a 549 Gene3D G3DSA:1.20.1270.20 145 228 4.4E-28 T 22-04-2016 IPR016100 Prismane, alpha-bundle GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 L21SP4_RS08140 5b703a94d14d188f5111a161463e960a 549 PANTHER PTHR30109:SF0 1 548 1.5E-280 T 22-04-2016 L21SP4_RS08140 5b703a94d14d188f5111a161463e960a 549 Gene3D G3DSA:1.20.1270.20 1 103 7.5E-38 T 22-04-2016 IPR016100 Prismane, alpha-bundle GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 L21SP4_RS08140 5b703a94d14d188f5111a161463e960a 549 PIRSF PIRSF000076 1 549 1.5E-233 T 22-04-2016 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 L21SP4_RS08140 5b703a94d14d188f5111a161463e960a 549 Gene3D G3DSA:3.40.50.2030 230 379 7.0E-70 T 22-04-2016 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 L21SP4_RS08140 5b703a94d14d188f5111a161463e960a 549 Hamap MF_00069 Hydroxylamine reductase [hcp]. 1 549 21.254 T 22-04-2016 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 L21SP4_RS08140 5b703a94d14d188f5111a161463e960a 549 TIGRFAM TIGR01703 hybrid_clust: hydroxylamine reductase 1 548 2.7E-229 T 22-04-2016 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 L21SP4_RS11045 89ac11d20a968f57910acd4f5e26ecc3 193 SUPERFAMILY SSF52833 6 192 6.88E-54 T 22-04-2016 IPR012336 Thioredoxin-like fold L21SP4_RS11045 89ac11d20a968f57910acd4f5e26ecc3 193 PANTHER PTHR10681:SF91 2 188 3.7E-69 T 22-04-2016 L21SP4_RS11045 89ac11d20a968f57910acd4f5e26ecc3 193 PANTHER PTHR10681 2 188 3.7E-69 T 22-04-2016 L21SP4_RS11045 89ac11d20a968f57910acd4f5e26ecc3 193 Pfam PF00578 AhpC/TSA family 12 136 2.9E-17 T 22-04-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15 L21SP4_RS11045 89ac11d20a968f57910acd4f5e26ecc3 193 Gene3D G3DSA:3.40.30.10 11 176 1.0E-30 T 22-04-2016 IPR012336 Thioredoxin-like fold L21SP4_RS07080 0df743c86345a7019ffcbb85fb2acb96 422 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 212 272 1.4E-14 T 22-04-2016 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain L21SP4_RS07080 0df743c86345a7019ffcbb85fb2acb96 422 SUPERFAMILY SSF81891 183 378 1.7E-33 T 22-04-2016 L21SP4_RS07080 0df743c86345a7019ffcbb85fb2acb96 422 PANTHER PTHR13734:SF47 21 275 4.2E-101 T 22-04-2016 L21SP4_RS07080 0df743c86345a7019ffcbb85fb2acb96 422 Gene3D G3DSA:1.10.3090.10 185 390 2.9E-36 T 22-04-2016 L21SP4_RS07080 0df743c86345a7019ffcbb85fb2acb96 422 TIGRFAM TIGR01942 pcnB: poly(A) polymerase 21 415 3.4E-113 T 22-04-2016 IPR010206 Poly(A) polymerase I GO:0003723|GO:0004652|GO:0006378 L21SP4_RS07080 0df743c86345a7019ffcbb85fb2acb96 422 PANTHER PTHR13734 21 275 4.2E-101 T 22-04-2016 L21SP4_RS07080 0df743c86345a7019ffcbb85fb2acb96 422 Hamap MF_00957 Poly(A) polymerase I [pcnB]. 9 422 31.313 T 22-04-2016 IPR010206 Poly(A) polymerase I GO:0003723|GO:0004652|GO:0006378 L21SP4_RS07080 0df743c86345a7019ffcbb85fb2acb96 422 Gene3D G3DSA:3.30.460.10 34 184 4.1E-46 T 22-04-2016 L21SP4_RS07080 0df743c86345a7019ffcbb85fb2acb96 422 SUPERFAMILY SSF81301 27 182 1.42E-37 T 22-04-2016 L21SP4_RS07080 0df743c86345a7019ffcbb85fb2acb96 422 Pfam PF01743 Poly A polymerase head domain 52 185 1.9E-36 T 22-04-2016 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 L21SP4_RS07080 0df743c86345a7019ffcbb85fb2acb96 422 Pfam PF12626 Polymerase A arginine-rich C-terminus 331 415 8.1E-10 T 22-04-2016 IPR025866 Polymerase A arginine-rich C-terminal domain L21SP4_RS05485 29a6d358684f2202498f6ced0ab875f7 364 Gene3D G3DSA:3.40.50.2000 159 341 8.5E-50 T 22-04-2016 L21SP4_RS05485 29a6d358684f2202498f6ced0ab875f7 364 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 187 340 2.6E-34 T 22-04-2016 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 L21SP4_RS05485 29a6d358684f2202498f6ced0ab875f7 364 PANTHER PTHR21015:SF22 3 341 5.6E-76 T 22-04-2016 L21SP4_RS05485 29a6d358684f2202498f6ced0ab875f7 364 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 8 360 27.823 T 22-04-2016 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 L21SP4_RS05485 29a6d358684f2202498f6ced0ab875f7 364 SUPERFAMILY SSF53756 7 358 2.03E-87 T 22-04-2016 L21SP4_RS05485 29a6d358684f2202498f6ced0ab875f7 364 PANTHER PTHR21015 3 341 5.6E-76 T 22-04-2016 L21SP4_RS05485 29a6d358684f2202498f6ced0ab875f7 364 Gene3D G3DSA:3.40.50.2000 7 136 1.8E-6 T 22-04-2016 L21SP4_RS05485 29a6d358684f2202498f6ced0ab875f7 364 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 8 144 3.5E-25 T 22-04-2016 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 L21SP4_RS11095 f9f36e354551df86c81b602273a3e2c7 158 Pfam PF05258 Protein of unknown function (DUF721) 58 144 6.0E-18 T 22-04-2016 IPR007922 Protein of unknown function DUF721/UPF0232 L21SP4_RS11095 f9f36e354551df86c81b602273a3e2c7 158 PANTHER PTHR36456 42 154 5.4E-12 T 22-04-2016 L21SP4_RS01900 b9332fdb0160633b7b1cdc706cba71ed 119 SUPERFAMILY SSF75138 25 110 9.29E-11 T 22-04-2016 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like L21SP4_RS01900 b9332fdb0160633b7b1cdc706cba71ed 119 Gene3D G3DSA:3.40.1390.20 29 111 2.5E-7 T 22-04-2016 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like L21SP4_RS10660 63ef7fbd300ac3641eecd37c970dca5b 245 PANTHER PTHR30027 1 242 9.8E-62 T 22-04-2016 L21SP4_RS10660 63ef7fbd300ac3641eecd37c970dca5b 245 PIRSF PIRSF015601 1 244 1.2E-54 T 22-04-2016 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 L21SP4_RS10660 63ef7fbd300ac3641eecd37c970dca5b 245 Gene3D G3DSA:3.40.1280.10 6 241 8.0E-70 T 22-04-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal L21SP4_RS10660 63ef7fbd300ac3641eecd37c970dca5b 245 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 3 242 2.8E-42 T 22-04-2016 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 L21SP4_RS10660 63ef7fbd300ac3641eecd37c970dca5b 245 Pfam PF04452 RNA methyltransferase 18 240 6.5E-61 T 22-04-2016 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 L21SP4_RS10660 63ef7fbd300ac3641eecd37c970dca5b 245 SUPERFAMILY SSF88697 5 71 1.99E-12 T 22-04-2016 IPR015947 PUA-like domain L21SP4_RS10660 63ef7fbd300ac3641eecd37c970dca5b 245 PANTHER PTHR30027:SF3 1 242 9.8E-62 T 22-04-2016 L21SP4_RS10660 63ef7fbd300ac3641eecd37c970dca5b 245 SUPERFAMILY SSF75217 73 240 1.62E-42 T 22-04-2016 IPR029028 Alpha/beta knot methyltransferases L21SP4_RS00130 99c3aa88267749723143533b983d7893 634 SMART SM01228 556 627 2.2E-25 T 22-04-2016 L21SP4_RS00130 99c3aa88267749723143533b983d7893 634 Pfam PF13932 GidA associated domain 435 625 3.7E-60 T 22-04-2016 IPR026904 GidA associated domain 3 L21SP4_RS00130 99c3aa88267749723143533b983d7893 634 SUPERFAMILY SSF51905 98 243 5.77E-34 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP4_RS00130 99c3aa88267749723143533b983d7893 634 SUPERFAMILY SSF51905 5 67 5.77E-34 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP4_RS00130 99c3aa88267749723143533b983d7893 634 SUPERFAMILY SSF51905 275 292 5.77E-34 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP4_RS00130 99c3aa88267749723143533b983d7893 634 Pfam PF01134 Glucose inhibited division protein A 8 431 2.9E-143 T 22-04-2016 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 L21SP4_RS00130 99c3aa88267749723143533b983d7893 634 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 401 424 - T 22-04-2016 IPR020595 MnmG-related, conserved site L21SP4_RS00130 99c3aa88267749723143533b983d7893 634 Gene3D G3DSA:3.50.50.60 6 218 8.2E-28 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP4_RS00130 99c3aa88267749723143533b983d7893 634 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 306 320 - T 22-04-2016 IPR020595 MnmG-related, conserved site L21SP4_RS00130 99c3aa88267749723143533b983d7893 634 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 4 634 38.316 T 22-04-2016 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 L21SP4_RS00130 99c3aa88267749723143533b983d7893 634 PANTHER PTHR11806 264 631 3.8E-277 T 22-04-2016 L21SP4_RS00130 99c3aa88267749723143533b983d7893 634 PANTHER PTHR11806 2 231 3.8E-277 T 22-04-2016 L21SP4_RS00130 99c3aa88267749723143533b983d7893 634 PANTHER PTHR11806:SF0 264 631 3.8E-277 T 22-04-2016 L21SP4_RS00130 99c3aa88267749723143533b983d7893 634 PANTHER PTHR11806:SF0 2 231 3.8E-277 T 22-04-2016 L21SP4_RS12085 bf19223cc075d90008687cdcce7df993 514 PANTHER PTHR12826 184 513 1.0E-109 T 22-04-2016 L21SP4_RS12085 bf19223cc075d90008687cdcce7df993 514 Pfam PF12072 Domain of unknown function (DUF3552) 12 198 2.0E-36 T 22-04-2016 IPR022711 Ribonuclease Y, N-terminal L21SP4_RS12085 bf19223cc075d90008687cdcce7df993 514 SMART SM00471 326 432 2.4E-8 T 22-04-2016 IPR003607 HD/PDEase domain L21SP4_RS12085 bf19223cc075d90008687cdcce7df993 514 Pfam PF01966 HD domain 330 422 6.4E-15 T 22-04-2016 IPR006674 HD domain L21SP4_RS12085 bf19223cc075d90008687cdcce7df993 514 SUPERFAMILY SSF109604 306 448 1.21E-23 T 22-04-2016 L21SP4_RS12085 bf19223cc075d90008687cdcce7df993 514 SUPERFAMILY SSF54791 201 298 4.71E-15 T 22-04-2016 IPR004088 K Homology domain, type 1 GO:0003723 L21SP4_RS12085 bf19223cc075d90008687cdcce7df993 514 SMART SM00322 202 269 5.3E-9 T 22-04-2016 IPR004087 K Homology domain GO:0003676 L21SP4_RS12085 bf19223cc075d90008687cdcce7df993 514 Pfam PF00013 KH domain 205 261 2.4E-7 T 22-04-2016 IPR004088 K Homology domain, type 1 GO:0003723 L21SP4_RS12085 bf19223cc075d90008687cdcce7df993 514 TIGRFAM TIGR03319 RNase_Y: ribonuclease Y 11 514 7.7E-195 T 22-04-2016 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 L21SP4_RS12085 bf19223cc075d90008687cdcce7df993 514 Hamap MF_00335 Ribonuclease Y [rny]. 3 514 23.018 T 22-04-2016 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 L21SP4_RS12085 bf19223cc075d90008687cdcce7df993 514 Gene3D G3DSA:1.10.3210.10 311 490 3.7E-35 T 22-04-2016 IPR006674 HD domain L21SP4_RS12085 bf19223cc075d90008687cdcce7df993 514 TIGRFAM TIGR00277 HDIG: HDIG domain 326 402 1.6E-20 T 22-04-2016 IPR006675 HDIG domain L21SP4_RS12085 bf19223cc075d90008687cdcce7df993 514 Gene3D G3DSA:3.30.1370.10 214 270 4.4E-6 T 22-04-2016 IPR004088 K Homology domain, type 1 GO:0003723 L21SP4_RS08630 468a0ced5800a6bbd6090135a8ad1f05 452 SUPERFAMILY SSF63418 8 109 3.53E-20 T 22-04-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 L21SP4_RS08630 468a0ced5800a6bbd6090135a8ad1f05 452 Pfam PF01225 Mur ligase family, catalytic domain 29 105 3.2E-7 T 22-04-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 L21SP4_RS08630 468a0ced5800a6bbd6090135a8ad1f05 452 PANTHER PTHR23135 15 450 1.8E-131 T 22-04-2016 L21SP4_RS08630 468a0ced5800a6bbd6090135a8ad1f05 452 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 33 445 9.6E-113 T 22-04-2016 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 L21SP4_RS08630 468a0ced5800a6bbd6090135a8ad1f05 452 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 7 448 29.705 T 22-04-2016 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 L21SP4_RS08630 468a0ced5800a6bbd6090135a8ad1f05 452 SUPERFAMILY SSF53244 315 446 9.71E-35 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 L21SP4_RS08630 468a0ced5800a6bbd6090135a8ad1f05 452 Gene3D G3DSA:3.40.1190.10 102 312 1.1E-52 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 L21SP4_RS08630 468a0ced5800a6bbd6090135a8ad1f05 452 Pfam PF02875 Mur ligase family, glutamate ligase domain 315 395 2.7E-16 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 L21SP4_RS08630 468a0ced5800a6bbd6090135a8ad1f05 452 Pfam PF08245 Mur ligase middle domain 117 294 1.9E-32 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 L21SP4_RS08630 468a0ced5800a6bbd6090135a8ad1f05 452 Gene3D G3DSA:3.90.190.20 315 447 7.0E-38 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 L21SP4_RS08630 468a0ced5800a6bbd6090135a8ad1f05 452 PANTHER PTHR23135:SF3 15 450 1.8E-131 T 22-04-2016 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 L21SP4_RS08630 468a0ced5800a6bbd6090135a8ad1f05 452 Gene3D G3DSA:3.40.1390.10 13 101 8.4E-20 T 22-04-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 L21SP4_RS08630 468a0ced5800a6bbd6090135a8ad1f05 452 SUPERFAMILY SSF53623 113 311 1.44E-43 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 L21SP4_RS04110 b60ce7d15f726dc3daa33728dcf49d34 260 Gene3D G3DSA:3.40.50.150 91 127 5.7E-5 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS04110 b60ce7d15f726dc3daa33728dcf49d34 260 SUPERFAMILY SSF53335 59 239 3.32E-21 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS04110 b60ce7d15f726dc3daa33728dcf49d34 260 Pfam PF01479 S4 domain 5 51 1.1E-12 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 L21SP4_RS04110 b60ce7d15f726dc3daa33728dcf49d34 260 SUPERFAMILY SSF55174 5 67 6.48E-14 T 22-04-2016 L21SP4_RS04110 b60ce7d15f726dc3daa33728dcf49d34 260 SMART SM00363 4 66 7.7E-12 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 L21SP4_RS04110 b60ce7d15f726dc3daa33728dcf49d34 260 Gene3D G3DSA:3.10.290.10 5 90 6.9E-26 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 L21SP4_RS04110 b60ce7d15f726dc3daa33728dcf49d34 260 PIRSF PIRSF005578 1 257 7.4E-99 T 22-04-2016 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 L21SP4_RS04110 b60ce7d15f726dc3daa33728dcf49d34 260 PANTHER PTHR32319 1 249 4.6E-124 T 22-04-2016 L21SP4_RS04110 b60ce7d15f726dc3daa33728dcf49d34 260 TIGRFAM TIGR00478 tly: TlyA family rRNA methyltransferase/putative hemolysin 5 236 5.8E-72 T 22-04-2016 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 L21SP4_RS04110 b60ce7d15f726dc3daa33728dcf49d34 260 PANTHER PTHR32319:SF0 1 249 4.6E-124 T 22-04-2016 L21SP4_RS04110 b60ce7d15f726dc3daa33728dcf49d34 260 Pfam PF01728 FtsJ-like methyltransferase 59 211 1.3E-18 T 22-04-2016 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 L21SP4_RS09400 b7155c2bf7eaa0ec425ae15d0eeda3b6 1011 Gene3D G3DSA:1.25.10.10 307 397 1.8E-4 T 22-04-2016 IPR011989 Armadillo-like helical L21SP4_RS09400 b7155c2bf7eaa0ec425ae15d0eeda3b6 1011 Gene3D G3DSA:1.25.10.10 652 821 3.4E-13 T 22-04-2016 IPR011989 Armadillo-like helical L21SP4_RS09400 b7155c2bf7eaa0ec425ae15d0eeda3b6 1011 Gene3D G3DSA:1.25.10.10 408 651 2.6E-18 T 22-04-2016 IPR011989 Armadillo-like helical L21SP4_RS09400 b7155c2bf7eaa0ec425ae15d0eeda3b6 1011 PANTHER PTHR12110 119 300 1.5E-23 T 22-04-2016 L21SP4_RS09400 b7155c2bf7eaa0ec425ae15d0eeda3b6 1011 Gene3D G3DSA:3.20.20.150 48 285 2.8E-31 T 22-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain L21SP4_RS09400 b7155c2bf7eaa0ec425ae15d0eeda3b6 1011 PANTHER PTHR12110:SF21 119 300 1.5E-23 T 22-04-2016 L21SP4_RS09400 b7155c2bf7eaa0ec425ae15d0eeda3b6 1011 SUPERFAMILY SSF48371 324 460 4.22E-8 T 22-04-2016 IPR016024 Armadillo-type fold GO:0005488 L21SP4_RS09400 b7155c2bf7eaa0ec425ae15d0eeda3b6 1011 Pfam PF13646 HEAT repeats 756 818 7.5E-7 T 22-04-2016 L21SP4_RS09400 b7155c2bf7eaa0ec425ae15d0eeda3b6 1011 Pfam PF13646 HEAT repeats 407 468 1.8E-6 T 22-04-2016 L21SP4_RS09400 b7155c2bf7eaa0ec425ae15d0eeda3b6 1011 Pfam PF13646 HEAT repeats 557 637 6.0E-7 T 22-04-2016 L21SP4_RS09400 b7155c2bf7eaa0ec425ae15d0eeda3b6 1011 SUPERFAMILY SSF48371 485 641 4.85E-21 T 22-04-2016 IPR016024 Armadillo-type fold GO:0005488 L21SP4_RS09400 b7155c2bf7eaa0ec425ae15d0eeda3b6 1011 SUPERFAMILY SSF48371 672 838 4.85E-21 T 22-04-2016 IPR016024 Armadillo-type fold GO:0005488 L21SP4_RS09400 b7155c2bf7eaa0ec425ae15d0eeda3b6 1011 SMART SM00567 E-Z type HEAT repeats 756 785 23.0 T 22-04-2016 IPR004155 PBS lyase HEAT-like repeat L21SP4_RS09400 b7155c2bf7eaa0ec425ae15d0eeda3b6 1011 SMART SM00567 E-Z type HEAT repeats 595 624 750.0 T 22-04-2016 IPR004155 PBS lyase HEAT-like repeat L21SP4_RS09400 b7155c2bf7eaa0ec425ae15d0eeda3b6 1011 SMART SM00567 E-Z type HEAT repeats 401 430 360.0 T 22-04-2016 IPR004155 PBS lyase HEAT-like repeat L21SP4_RS09400 b7155c2bf7eaa0ec425ae15d0eeda3b6 1011 SMART SM00567 E-Z type HEAT repeats 502 531 110.0 T 22-04-2016 IPR004155 PBS lyase HEAT-like repeat L21SP4_RS09400 b7155c2bf7eaa0ec425ae15d0eeda3b6 1011 SMART SM00567 E-Z type HEAT repeats 564 593 160.0 T 22-04-2016 IPR004155 PBS lyase HEAT-like repeat L21SP4_RS09400 b7155c2bf7eaa0ec425ae15d0eeda3b6 1011 SMART SM00567 E-Z type HEAT repeats 434 463 6.4 T 22-04-2016 IPR004155 PBS lyase HEAT-like repeat L21SP4_RS09400 b7155c2bf7eaa0ec425ae15d0eeda3b6 1011 SMART SM00567 E-Z type HEAT repeats 341 370 100.0 T 22-04-2016 IPR004155 PBS lyase HEAT-like repeat L21SP4_RS09400 b7155c2bf7eaa0ec425ae15d0eeda3b6 1011 SMART SM00567 E-Z type HEAT repeats 787 816 0.43 T 22-04-2016 IPR004155 PBS lyase HEAT-like repeat L21SP4_RS09400 b7155c2bf7eaa0ec425ae15d0eeda3b6 1011 Pfam PF01261 Xylose isomerase-like TIM barrel 76 230 6.5E-12 T 22-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain L21SP4_RS09400 b7155c2bf7eaa0ec425ae15d0eeda3b6 1011 SUPERFAMILY SSF51658 49 286 5.67E-31 T 22-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain L21SP4_RS01420 1919bf7cd15d7cd426f5acb924ee3f23 603 Pfam PF00989 PAS fold 252 359 5.0E-7 T 22-04-2016 IPR013767 PAS fold GO:0006355 L21SP4_RS01420 1919bf7cd15d7cd426f5acb924ee3f23 603 Pfam PF00512 His Kinase A (phospho-acceptor) domain 369 433 5.8E-20 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS01420 1919bf7cd15d7cd426f5acb924ee3f23 603 SUPERFAMILY SSF103190 59 161 1.02E-7 T 22-04-2016 IPR029151 Periplasmic sensor domain-like L21SP4_RS01420 1919bf7cd15d7cd426f5acb924ee3f23 603 SMART SM00304 192 244 5.7E-13 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 L21SP4_RS01420 1919bf7cd15d7cd426f5acb924ee3f23 603 SMART SM00091 251 317 3.4E-5 T 22-04-2016 IPR000014 PAS domain L21SP4_RS01420 1919bf7cd15d7cd426f5acb924ee3f23 603 PRINTS PR00344 Bacterial sensor protein C-terminal signature 537 547 6.0E-18 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS01420 1919bf7cd15d7cd426f5acb924ee3f23 603 PRINTS PR00344 Bacterial sensor protein C-terminal signature 519 533 6.0E-18 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS01420 1919bf7cd15d7cd426f5acb924ee3f23 603 PRINTS PR00344 Bacterial sensor protein C-terminal signature 554 572 6.0E-18 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS01420 1919bf7cd15d7cd426f5acb924ee3f23 603 PRINTS PR00344 Bacterial sensor protein C-terminal signature 578 591 6.0E-18 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS01420 1919bf7cd15d7cd426f5acb924ee3f23 603 Pfam PF00672 HAMP domain 173 240 1.1E-16 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 L21SP4_RS01420 1919bf7cd15d7cd426f5acb924ee3f23 603 SUPERFAMILY SSF55785 244 360 1.52E-10 T 22-04-2016 IPR000014 PAS domain L21SP4_RS01420 1919bf7cd15d7cd426f5acb924ee3f23 603 SMART SM00388 368 435 5.6E-22 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS01420 1919bf7cd15d7cd426f5acb924ee3f23 603 SUPERFAMILY SSF55874 436 593 6.16E-47 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS01420 1919bf7cd15d7cd426f5acb924ee3f23 603 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 487 593 8.8E-26 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS01420 1919bf7cd15d7cd426f5acb924ee3f23 603 SUPERFAMILY SSF47384 354 433 4.71E-19 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS01420 1919bf7cd15d7cd426f5acb924ee3f23 603 SUPERFAMILY SSF158472 192 241 4.45E-10 T 22-04-2016 L21SP4_RS01420 1919bf7cd15d7cd426f5acb924ee3f23 603 PANTHER PTHR24423 132 156 1.6E-98 T 22-04-2016 L21SP4_RS01420 1919bf7cd15d7cd426f5acb924ee3f23 603 PANTHER PTHR24423 218 596 1.6E-98 T 22-04-2016 L21SP4_RS01420 1919bf7cd15d7cd426f5acb924ee3f23 603 Pfam PF16736 Single Cache-like 36 156 3.5E-7 T 22-04-2016 IPR031967 PhoR, single Cache-like domain L21SP4_RS01420 1919bf7cd15d7cd426f5acb924ee3f23 603 Gene3D G3DSA:1.10.287.130 360 420 1.2E-21 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS01420 1919bf7cd15d7cd426f5acb924ee3f23 603 SMART SM00387 482 594 8.8E-43 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS01420 1919bf7cd15d7cd426f5acb924ee3f23 603 Gene3D G3DSA:3.30.450.20 246 359 4.9E-13 T 22-04-2016 L21SP4_RS01420 1919bf7cd15d7cd426f5acb924ee3f23 603 Gene3D G3DSA:3.30.565.10 421 594 1.8E-48 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS01420 1919bf7cd15d7cd426f5acb924ee3f23 603 Gene3D G3DSA:3.30.450.20 34 163 6.4E-14 T 22-04-2016 L21SP4_RS00460 6b192b76a3fb97af25d3def5f329c8fc 515 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 364 489 9.9E-24 T 22-04-2016 IPR000014 PAS domain L21SP4_RS00460 6b192b76a3fb97af25d3def5f329c8fc 515 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 244 366 7.7E-20 T 22-04-2016 IPR000014 PAS domain L21SP4_RS00460 6b192b76a3fb97af25d3def5f329c8fc 515 SMART SM00086 318 360 4.4E-4 T 22-04-2016 IPR001610 PAC motif L21SP4_RS00460 6b192b76a3fb97af25d3def5f329c8fc 515 SMART SM00086 440 482 3.2E-4 T 22-04-2016 IPR001610 PAC motif L21SP4_RS00460 6b192b76a3fb97af25d3def5f329c8fc 515 SMART SM00091 247 313 7.0E-10 T 22-04-2016 IPR000014 PAS domain L21SP4_RS00460 6b192b76a3fb97af25d3def5f329c8fc 515 SMART SM00091 368 434 6.7E-11 T 22-04-2016 IPR000014 PAS domain L21SP4_RS00460 6b192b76a3fb97af25d3def5f329c8fc 515 Gene3D G3DSA:3.30.450.40 84 244 5.6E-18 T 22-04-2016 IPR029016 GAF domain-like L21SP4_RS00460 6b192b76a3fb97af25d3def5f329c8fc 515 SUPERFAMILY SSF55785 238 358 3.77E-23 T 22-04-2016 IPR000014 PAS domain L21SP4_RS00460 6b192b76a3fb97af25d3def5f329c8fc 515 SUPERFAMILY SSF55781 100 250 1.16E-14 T 22-04-2016 IPR029016 GAF domain-like L21SP4_RS00460 6b192b76a3fb97af25d3def5f329c8fc 515 Gene3D G3DSA:3.30.450.20 245 358 2.4E-22 T 22-04-2016 L21SP4_RS00460 6b192b76a3fb97af25d3def5f329c8fc 515 Pfam PF13426 PAS domain 379 481 4.7E-18 T 22-04-2016 IPR000014 PAS domain L21SP4_RS00460 6b192b76a3fb97af25d3def5f329c8fc 515 SUPERFAMILY SSF55785 374 480 4.05E-30 T 22-04-2016 IPR000014 PAS domain L21SP4_RS00460 6b192b76a3fb97af25d3def5f329c8fc 515 Pfam PF00989 PAS fold 251 357 3.2E-14 T 22-04-2016 IPR013767 PAS fold GO:0006355 L21SP4_RS00460 6b192b76a3fb97af25d3def5f329c8fc 515 PANTHER PTHR24423 233 502 1.3E-36 T 22-04-2016 L21SP4_RS00460 6b192b76a3fb97af25d3def5f329c8fc 515 Pfam PF13185 GAF domain 100 238 4.4E-9 T 22-04-2016 IPR003018 GAF domain GO:0005515 L21SP4_RS00460 6b192b76a3fb97af25d3def5f329c8fc 515 Gene3D G3DSA:3.30.450.20 379 481 3.9E-29 T 22-04-2016 L21SP4_RS00500 06fc2ffafdd4f97273530deb41d5c1eb 203 SUPERFAMILY SSF49785 21 201 9.69E-7 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS00500 06fc2ffafdd4f97273530deb41d5c1eb 203 Gene3D G3DSA:2.60.120.260 15 203 1.5E-13 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS04220 24d58948aa4726dfc22a7a1c12731f43 278 SUPERFAMILY SSF109635 152 234 9.81E-13 T 22-04-2016 L21SP4_RS04220 24d58948aa4726dfc22a7a1c12731f43 278 SUPERFAMILY SSF57716 235 273 2.42E-6 T 22-04-2016 L21SP4_RS04220 24d58948aa4726dfc22a7a1c12731f43 278 PRINTS PR00624 Histone H5 signature 70 87 5.2E-5 T 22-04-2016 IPR005819 Histone H5 GO:0000786|GO:0003677|GO:0006334 L21SP4_RS04220 24d58948aa4726dfc22a7a1c12731f43 278 PRINTS PR00624 Histone H5 signature 1 25 5.2E-5 T 22-04-2016 IPR005819 Histone H5 GO:0000786|GO:0003677|GO:0006334 L21SP4_RS04220 24d58948aa4726dfc22a7a1c12731f43 278 PRINTS PR00624 Histone H5 signature 92 111 5.2E-5 T 22-04-2016 IPR005819 Histone H5 GO:0000786|GO:0003677|GO:0006334 L21SP4_RS04220 24d58948aa4726dfc22a7a1c12731f43 278 PRINTS PR00624 Histone H5 signature 39 53 5.2E-5 T 22-04-2016 IPR005819 Histone H5 GO:0000786|GO:0003677|GO:0006334 L21SP4_RS04220 24d58948aa4726dfc22a7a1c12731f43 278 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 233 264 7.5E-8 T 22-04-2016 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 L21SP4_RS04220 24d58948aa4726dfc22a7a1c12731f43 278 PANTHER PTHR33823 159 276 4.1E-25 T 22-04-2016 L21SP4_RS04220 24d58948aa4726dfc22a7a1c12731f43 278 ProSitePatterns PS01102 Prokaryotic dksA C4-type zinc finger. 238 262 - T 22-04-2016 IPR020458 Zinc finger, DksA/TraR C4-type conserved site L21SP4_RS11210 11ddb9c7bc05dc46590b90252d8eafb6 243 Gene3D G3DSA:3.40.50.150 37 188 4.3E-18 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS11210 11ddb9c7bc05dc46590b90252d8eafb6 243 SUPERFAMILY SSF53335 36 161 1.67E-19 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS11210 11ddb9c7bc05dc46590b90252d8eafb6 243 Pfam PF13489 Methyltransferase domain 44 173 8.9E-9 T 22-04-2016 L21SP4_RS06140 e7695a6816d74dcb6e66eefde87b23a5 373 Gene3D G3DSA:2.40.37.10 225 372 5.7E-52 T 22-04-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 L21SP4_RS06140 e7695a6816d74dcb6e66eefde87b23a5 373 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 38 47 - T 22-04-2016 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 L21SP4_RS06140 e7695a6816d74dcb6e66eefde87b23a5 373 PRINTS PR00992 Alanine racemase signature 68 86 6.0E-46 T 22-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 L21SP4_RS06140 e7695a6816d74dcb6e66eefde87b23a5 373 PRINTS PR00992 Alanine racemase signature 206 233 6.0E-46 T 22-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 L21SP4_RS06140 e7695a6816d74dcb6e66eefde87b23a5 373 PRINTS PR00992 Alanine racemase signature 129 141 6.0E-46 T 22-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 L21SP4_RS06140 e7695a6816d74dcb6e66eefde87b23a5 373 PRINTS PR00992 Alanine racemase signature 299 316 6.0E-46 T 22-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 L21SP4_RS06140 e7695a6816d74dcb6e66eefde87b23a5 373 PRINTS PR00992 Alanine racemase signature 163 174 6.0E-46 T 22-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 L21SP4_RS06140 e7695a6816d74dcb6e66eefde87b23a5 373 PRINTS PR00992 Alanine racemase signature 278 293 6.0E-46 T 22-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 L21SP4_RS06140 e7695a6816d74dcb6e66eefde87b23a5 373 PRINTS PR00992 Alanine racemase signature 355 368 6.0E-46 T 22-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 L21SP4_RS06140 e7695a6816d74dcb6e66eefde87b23a5 373 PRINTS PR00992 Alanine racemase signature 261 276 6.0E-46 T 22-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 L21SP4_RS06140 e7695a6816d74dcb6e66eefde87b23a5 373 PRINTS PR00992 Alanine racemase signature 32 48 6.0E-46 T 22-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 L21SP4_RS06140 e7695a6816d74dcb6e66eefde87b23a5 373 SUPERFAMILY SSF50621 240 372 3.49E-44 T 22-04-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 L21SP4_RS06140 e7695a6816d74dcb6e66eefde87b23a5 373 Pfam PF01168 Alanine racemase, N-terminal domain 13 231 6.2E-60 T 22-04-2016 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 L21SP4_RS06140 e7695a6816d74dcb6e66eefde87b23a5 373 Pfam PF00842 Alanine racemase, C-terminal domain 246 372 2.6E-35 T 22-04-2016 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 L21SP4_RS06140 e7695a6816d74dcb6e66eefde87b23a5 373 PANTHER PTHR30511:SF0 3 373 2.7E-124 T 22-04-2016 L21SP4_RS06140 e7695a6816d74dcb6e66eefde87b23a5 373 Gene3D G3DSA:3.20.20.10 15 224 1.4E-59 T 22-04-2016 IPR029066 PLP-binding barrel L21SP4_RS06140 e7695a6816d74dcb6e66eefde87b23a5 373 TIGRFAM TIGR00492 alr: alanine racemase 7 372 4.8E-93 T 22-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 L21SP4_RS06140 e7695a6816d74dcb6e66eefde87b23a5 373 SUPERFAMILY SSF51419 13 235 2.91E-56 T 22-04-2016 IPR029066 PLP-binding barrel L21SP4_RS06140 e7695a6816d74dcb6e66eefde87b23a5 373 Hamap MF_01201 Alanine racemase. 6 373 29.361 T 22-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 L21SP4_RS06140 e7695a6816d74dcb6e66eefde87b23a5 373 SMART SM01005 245 373 9.8E-57 T 22-04-2016 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 L21SP4_RS06140 e7695a6816d74dcb6e66eefde87b23a5 373 PANTHER PTHR30511 3 373 2.7E-124 T 22-04-2016 L21SP4_RS02990 4bedaac04dee225fd0eedc155d3e1ba6 73 SUPERFAMILY SSF82771 3 55 1.83E-7 T 22-04-2016 IPR000305 GIY-YIG nuclease superfamily L21SP4_RS02990 4bedaac04dee225fd0eedc155d3e1ba6 73 Pfam PF01541 GIY-YIG catalytic domain 3 53 3.5E-7 T 22-04-2016 IPR000305 GIY-YIG nuclease superfamily L21SP4_RS04165 548e1b492d42c5cfc6a888e9f4cf17e2 694 Pfam PF03572 Peptidase family S41 371 549 3.3E-45 T 22-04-2016 IPR005151 Tail specific protease GO:0006508|GO:0008236 L21SP4_RS04165 548e1b492d42c5cfc6a888e9f4cf17e2 694 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 252 325 3.2E-9 T 22-04-2016 IPR001478 PDZ domain GO:0005515 L21SP4_RS04165 548e1b492d42c5cfc6a888e9f4cf17e2 694 SMART SM00245 336 551 4.6E-60 T 22-04-2016 IPR005151 Tail specific protease GO:0006508|GO:0008236 L21SP4_RS04165 548e1b492d42c5cfc6a888e9f4cf17e2 694 PANTHER PTHR32060:SF11 186 624 4.6E-162 T 22-04-2016 L21SP4_RS04165 548e1b492d42c5cfc6a888e9f4cf17e2 694 Gene3D G3DSA:3.90.226.10 345 553 6.6E-57 T 22-04-2016 IPR029045 ClpP/crotonase-like domain L21SP4_RS04165 548e1b492d42c5cfc6a888e9f4cf17e2 694 Gene3D G3DSA:3.90.226.10 655 681 6.6E-57 T 22-04-2016 IPR029045 ClpP/crotonase-like domain L21SP4_RS04165 548e1b492d42c5cfc6a888e9f4cf17e2 694 Pfam PF11818 C-terminal domain of tail specific protease (DUF3340) 555 677 1.3E-21 T 22-04-2016 IPR020992 Tail specific protease, C-terminal L21SP4_RS04165 548e1b492d42c5cfc6a888e9f4cf17e2 694 Gene3D G3DSA:2.30.42.10 255 344 1.5E-16 T 22-04-2016 IPR001478 PDZ domain GO:0005515 L21SP4_RS04165 548e1b492d42c5cfc6a888e9f4cf17e2 694 PANTHER PTHR32060:SF11 19 161 4.6E-162 T 22-04-2016 L21SP4_RS04165 548e1b492d42c5cfc6a888e9f4cf17e2 694 SUPERFAMILY SSF52096 203 272 1.66E-60 T 22-04-2016 IPR029045 ClpP/crotonase-like domain L21SP4_RS04165 548e1b492d42c5cfc6a888e9f4cf17e2 694 SUPERFAMILY SSF52096 362 555 1.66E-60 T 22-04-2016 IPR029045 ClpP/crotonase-like domain L21SP4_RS04165 548e1b492d42c5cfc6a888e9f4cf17e2 694 SMART SM00228 254 331 3.5E-9 T 22-04-2016 IPR001478 PDZ domain GO:0005515 L21SP4_RS04165 548e1b492d42c5cfc6a888e9f4cf17e2 694 PANTHER PTHR32060 19 161 4.6E-162 T 22-04-2016 L21SP4_RS04165 548e1b492d42c5cfc6a888e9f4cf17e2 694 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 211 562 8.1E-83 T 22-04-2016 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 L21SP4_RS04165 548e1b492d42c5cfc6a888e9f4cf17e2 694 PANTHER PTHR32060 186 624 4.6E-162 T 22-04-2016 L21SP4_RS04165 548e1b492d42c5cfc6a888e9f4cf17e2 694 SUPERFAMILY SSF50156 254 328 5.19E-13 T 22-04-2016 IPR001478 PDZ domain GO:0005515 L21SP4_RS07995 958d60631aee1bd2c4a082bbe0fa5d1f 101 SUPERFAMILY SSF143011 12 98 8.63E-16 T 22-04-2016 L21SP4_RS07995 958d60631aee1bd2c4a082bbe0fa5d1f 101 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 41 100 5.8E-6 T 22-04-2016 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family L21SP4_RS10615 0d33609e1daf9cd63b586ba27e781d63 607 SMART SM00387 39 173 5.1E-9 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS10615 0d33609e1daf9cd63b586ba27e781d63 607 PANTHER PTHR10169 5 605 2.1E-247 T 22-04-2016 L21SP4_RS10615 0d33609e1daf9cd63b586ba27e781d63 607 Pfam PF00204 DNA gyrase B 233 364 8.2E-30 T 22-04-2016 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 L21SP4_RS10615 0d33609e1daf9cd63b586ba27e781d63 607 SUPERFAMILY SSF56719 390 598 3.14E-56 T 22-04-2016 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 L21SP4_RS10615 0d33609e1daf9cd63b586ba27e781d63 607 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 538 595 1.0E-7 T 22-04-2016 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 L21SP4_RS10615 0d33609e1daf9cd63b586ba27e781d63 607 Gene3D G3DSA:3.30.565.10 9 210 1.6E-51 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS10615 0d33609e1daf9cd63b586ba27e781d63 607 PANTHER PTHR10169:SF28 5 605 2.1E-247 T 22-04-2016 L21SP4_RS10615 0d33609e1daf9cd63b586ba27e781d63 607 Gene3D G3DSA:3.40.50.670 367 535 2.2E-54 T 22-04-2016 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 L21SP4_RS10615 0d33609e1daf9cd63b586ba27e781d63 607 PRINTS PR00418 DNA topoisomerase II family signature 253 266 1.2E-47 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 L21SP4_RS10615 0d33609e1daf9cd63b586ba27e781d63 607 PRINTS PR00418 DNA topoisomerase II family signature 43 58 1.2E-47 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 L21SP4_RS10615 0d33609e1daf9cd63b586ba27e781d63 607 PRINTS PR00418 DNA topoisomerase II family signature 481 498 1.2E-47 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 L21SP4_RS10615 0d33609e1daf9cd63b586ba27e781d63 607 PRINTS PR00418 DNA topoisomerase II family signature 401 415 1.2E-47 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 L21SP4_RS10615 0d33609e1daf9cd63b586ba27e781d63 607 PRINTS PR00418 DNA topoisomerase II family signature 541 557 1.2E-47 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 L21SP4_RS10615 0d33609e1daf9cd63b586ba27e781d63 607 PRINTS PR00418 DNA topoisomerase II family signature 501 513 1.2E-47 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 L21SP4_RS10615 0d33609e1daf9cd63b586ba27e781d63 607 PRINTS PR00418 DNA topoisomerase II family signature 77 90 1.2E-47 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 L21SP4_RS10615 0d33609e1daf9cd63b586ba27e781d63 607 PRINTS PR00418 DNA topoisomerase II family signature 463 479 1.2E-47 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 L21SP4_RS10615 0d33609e1daf9cd63b586ba27e781d63 607 PRINTS PR00418 DNA topoisomerase II family signature 112 126 1.2E-47 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 L21SP4_RS10615 0d33609e1daf9cd63b586ba27e781d63 607 SUPERFAMILY SSF55874 8 208 1.44E-43 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS10615 0d33609e1daf9cd63b586ba27e781d63 607 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 40 172 4.1E-10 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS10615 0d33609e1daf9cd63b586ba27e781d63 607 SUPERFAMILY SSF54211 225 366 7.4E-33 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold L21SP4_RS10615 0d33609e1daf9cd63b586ba27e781d63 607 Gene3D G3DSA:3.30.230.10 211 366 2.2E-37 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup L21SP4_RS10615 0d33609e1daf9cd63b586ba27e781d63 607 Pfam PF01751 Toprim domain 401 505 1.2E-11 T 22-04-2016 IPR006171 Toprim domain L21SP4_RS10615 0d33609e1daf9cd63b586ba27e781d63 607 SMART SM00433 43 600 4.1E-170 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 L21SP4_RS03750 e676ef53b87be7f94b988025e0fdadcb 362 PANTHER PTHR30469 1 360 2.7E-70 T 22-04-2016 L21SP4_RS03750 e676ef53b87be7f94b988025e0fdadcb 362 SUPERFAMILY SSF111369 60 271 1.57E-31 T 22-04-2016 L21SP4_RS03750 e676ef53b87be7f94b988025e0fdadcb 362 PANTHER PTHR30469:SF15 1 360 2.7E-70 T 22-04-2016 L21SP4_RS03750 e676ef53b87be7f94b988025e0fdadcb 362 Gene3D G3DSA:2.40.50.100 163 196 4.9E-17 T 22-04-2016 L21SP4_RS03750 e676ef53b87be7f94b988025e0fdadcb 362 Gene3D G3DSA:2.40.50.100 73 102 4.9E-17 T 22-04-2016 L21SP4_RS03750 e676ef53b87be7f94b988025e0fdadcb 362 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 63 269 4.4E-26 T 22-04-2016 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain L21SP4_RS03750 e676ef53b87be7f94b988025e0fdadcb 362 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 44 349 3.0E-72 T 22-04-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 L21SP4_RS00980 a07542c3e906c9e46ee9906cd19da871 401 Gene3D G3DSA:3.40.50.2000 181 377 1.5E-31 T 22-04-2016 L21SP4_RS00980 a07542c3e906c9e46ee9906cd19da871 401 PANTHER PTHR12526 1 133 1.6E-66 T 22-04-2016 L21SP4_RS00980 a07542c3e906c9e46ee9906cd19da871 401 PANTHER PTHR12526 153 399 1.6E-66 T 22-04-2016 L21SP4_RS00980 a07542c3e906c9e46ee9906cd19da871 401 SUPERFAMILY SSF53756 2 397 6.68E-80 T 22-04-2016 L21SP4_RS00980 a07542c3e906c9e46ee9906cd19da871 401 Pfam PF13439 Glycosyltransferase Family 4 16 196 1.2E-20 T 22-04-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain L21SP4_RS00980 a07542c3e906c9e46ee9906cd19da871 401 Pfam PF00534 Glycosyl transferases group 1 211 358 2.9E-28 T 22-04-2016 IPR001296 Glycosyl transferase, family 1 L21SP4_RS05935 54c57843960a12a3f23c9c33a9b9df24 341 PANTHER PTHR21091:SF2 165 340 2.8E-18 T 22-04-2016 L21SP4_RS05935 54c57843960a12a3f23c9c33a9b9df24 341 Gene3D G3DSA:3.20.20.210 5 340 2.0E-69 T 22-04-2016 L21SP4_RS05935 54c57843960a12a3f23c9c33a9b9df24 341 PANTHER PTHR21091 165 340 2.8E-18 T 22-04-2016 L21SP4_RS05935 54c57843960a12a3f23c9c33a9b9df24 341 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 5 340 5.7E-64 T 22-04-2016 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 L21SP4_RS05935 54c57843960a12a3f23c9c33a9b9df24 341 SUPERFAMILY SSF51726 4 340 8.63E-60 T 22-04-2016 L21SP4_RS09050 8a82ad6256e0cfdb68e01121467950c9 403 Gene3D G3DSA:3.30.70.260 270 339 4.7E-6 T 22-04-2016 L21SP4_RS09050 8a82ad6256e0cfdb68e01121467950c9 403 PANTHER PTHR21499 1 403 2.5E-158 T 22-04-2016 L21SP4_RS09050 8a82ad6256e0cfdb68e01121467950c9 403 Pfam PF13840 ACT domain 336 398 2.0E-16 T 22-04-2016 IPR027795 GATS-like ACT domain L21SP4_RS09050 8a82ad6256e0cfdb68e01121467950c9 403 PIRSF PIRSF000726 56 403 1.9E-129 T 22-04-2016 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 L21SP4_RS09050 8a82ad6256e0cfdb68e01121467950c9 403 Pfam PF00696 Amino acid kinase family 3 229 1.9E-53 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 L21SP4_RS09050 8a82ad6256e0cfdb68e01121467950c9 403 Pfam PF01842 ACT domain 268 326 7.7E-12 T 22-04-2016 IPR002912 ACT domain GO:0008152|GO:0016597 L21SP4_RS09050 8a82ad6256e0cfdb68e01121467950c9 403 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 63 401 5.1E-121 T 22-04-2016 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 L21SP4_RS09050 8a82ad6256e0cfdb68e01121467950c9 403 PANTHER PTHR21499:SF27 1 403 2.5E-158 T 22-04-2016 L21SP4_RS09050 8a82ad6256e0cfdb68e01121467950c9 403 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 22-04-2016 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 L21SP4_RS09050 8a82ad6256e0cfdb68e01121467950c9 403 SUPERFAMILY SSF55021 328 403 2.62E-25 T 22-04-2016 L21SP4_RS09050 8a82ad6256e0cfdb68e01121467950c9 403 Gene3D G3DSA:3.40.1160.10 1 244 1.6E-71 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 L21SP4_RS09050 8a82ad6256e0cfdb68e01121467950c9 403 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 3 402 5.3E-133 T 22-04-2016 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 L21SP4_RS09050 8a82ad6256e0cfdb68e01121467950c9 403 SUPERFAMILY SSF53633 3 242 4.06E-71 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 L21SP4_RS09050 8a82ad6256e0cfdb68e01121467950c9 403 SUPERFAMILY SSF55021 247 324 3.5E-21 T 22-04-2016 L21SP4_RS02385 f31f123408d1d44ecfeee0775f4a738f 337 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 154 6.2E-60 T 22-04-2016 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: REACT_474 L21SP4_RS02385 f31f123408d1d44ecfeee0775f4a738f 337 PANTHER PTHR10836 1 335 5.9E-204 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 L21SP4_RS02385 f31f123408d1d44ecfeee0775f4a738f 337 Gene3D G3DSA:3.30.360.10 163 318 3.8E-77 T 22-04-2016 L21SP4_RS02385 f31f123408d1d44ecfeee0775f4a738f 337 SUPERFAMILY SSF51735 3 169 7.38E-64 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS02385 f31f123408d1d44ecfeee0775f4a738f 337 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 328 1.6E-135 T 22-04-2016 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: REACT_474|UniPathway: UPA00109 L21SP4_RS02385 f31f123408d1d44ecfeee0775f4a738f 337 Gene3D G3DSA:3.40.50.720 1 162 1.6E-75 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS02385 f31f123408d1d44ecfeee0775f4a738f 337 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 152 159 - T 22-04-2016 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: REACT_474 L21SP4_RS02385 f31f123408d1d44ecfeee0775f4a738f 337 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 159 316 8.4E-69 T 22-04-2016 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: REACT_474 L21SP4_RS02385 f31f123408d1d44ecfeee0775f4a738f 337 PANTHER PTHR10836:SF50 1 335 5.9E-204 T 22-04-2016 L21SP4_RS02385 f31f123408d1d44ecfeee0775f4a738f 337 PIRSF PIRSF000149 1 337 4.8E-137 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 L21SP4_RS02385 f31f123408d1d44ecfeee0775f4a738f 337 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 175 191 4.6E-38 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 L21SP4_RS02385 f31f123408d1d44ecfeee0775f4a738f 337 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 272 287 4.6E-38 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 L21SP4_RS02385 f31f123408d1d44ecfeee0775f4a738f 337 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 148 166 4.6E-38 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 L21SP4_RS02385 f31f123408d1d44ecfeee0775f4a738f 337 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 232 249 4.6E-38 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 L21SP4_RS02385 f31f123408d1d44ecfeee0775f4a738f 337 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 109 122 4.6E-38 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 L21SP4_RS02385 f31f123408d1d44ecfeee0775f4a738f 337 SUPERFAMILY SSF55347 153 316 4.17E-73 T 22-04-2016 L21SP4_RS02385 f31f123408d1d44ecfeee0775f4a738f 337 SMART SM00846 3 154 1.1E-90 T 22-04-2016 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: REACT_474 L21SP4_RS12135 d85b3c90bd516f4ee7e6f7775eb8ff53 215 PANTHER PTHR35786 9 215 6.1E-68 T 22-04-2016 L21SP4_RS12135 d85b3c90bd516f4ee7e6f7775eb8ff53 215 Pfam PF02629 CoA binding domain 82 178 4.5E-18 T 22-04-2016 IPR003781 CoA-binding GO:0048037 L21SP4_RS12135 d85b3c90bd516f4ee7e6f7775eb8ff53 215 SUPERFAMILY SSF51735 84 205 8.76E-22 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS12135 d85b3c90bd516f4ee7e6f7775eb8ff53 215 Gene3D G3DSA:1.10.10.10 9 75 5.3E-17 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS12135 d85b3c90bd516f4ee7e6f7775eb8ff53 215 Gene3D G3DSA:3.40.50.720 77 206 4.6E-42 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS12135 d85b3c90bd516f4ee7e6f7775eb8ff53 215 SUPERFAMILY SSF46785 9 79 2.99E-12 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS12135 d85b3c90bd516f4ee7e6f7775eb8ff53 215 Pfam PF06971 Putative DNA-binding protein N-terminus 9 52 2.8E-14 T 22-04-2016 IPR009718 Rex DNA-binding, C-terminal domain GO:0005737|GO:0045892|GO:0051775 L21SP4_RS12135 d85b3c90bd516f4ee7e6f7775eb8ff53 215 Hamap MF_01131 Redox-sensing transcriptional repressor Rex [rex]. 1 209 30.437 T 22-04-2016 IPR022876 Redox-sensing transcriptional repressor Rex GO:0005737|GO:0045892|GO:0051775 L21SP4_RS12135 d85b3c90bd516f4ee7e6f7775eb8ff53 215 SMART SM00881 79 180 1.4E-15 T 22-04-2016 IPR003781 CoA-binding GO:0048037 L21SP4_RS01035 3d0c143af3b74295c39f6c6629edfce9 403 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 90 104 - T 22-04-2016 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 L21SP4_RS01035 3d0c143af3b74295c39f6c6629edfce9 403 PANTHER PTHR10314 16 398 2.6E-173 T 22-04-2016 L21SP4_RS01035 3d0c143af3b74295c39f6c6629edfce9 403 SUPERFAMILY SSF53686 12 396 3.27E-129 T 22-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme L21SP4_RS01035 3d0c143af3b74295c39f6c6629edfce9 403 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 11 398 47.575 T 22-04-2016 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 L21SP4_RS01035 3d0c143af3b74295c39f6c6629edfce9 403 PIRSF PIRSF001413 2 401 3.8E-147 T 22-04-2016 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 L21SP4_RS01035 3d0c143af3b74295c39f6c6629edfce9 403 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 16 396 1.1E-155 T 22-04-2016 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 L21SP4_RS01035 3d0c143af3b74295c39f6c6629edfce9 403 Gene3D G3DSA:3.40.50.1100 108 185 1.1E-16 T 22-04-2016 L21SP4_RS01035 3d0c143af3b74295c39f6c6629edfce9 403 Gene3D G3DSA:3.40.50.1100 186 397 3.9E-77 T 22-04-2016 L21SP4_RS01035 3d0c143af3b74295c39f6c6629edfce9 403 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 62 385 1.8E-43 T 22-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme L21SP4_RS01035 3d0c143af3b74295c39f6c6629edfce9 403 PANTHER PTHR10314:SF3 16 398 2.6E-173 T 22-04-2016 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 L21SP4_RS08935 293629a04c70cc4c17398539ccb6d0e4 1001 SUPERFAMILY SSF56042 438 654 7.78E-43 T 22-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain L21SP4_RS08935 293629a04c70cc4c17398539ccb6d0e4 1001 Pfam PF00586 AIR synthase related protein, N-terminal domain 301 423 5.8E-5 T 22-04-2016 IPR016188 PurM-like, N-terminal domain L21SP4_RS08935 293629a04c70cc4c17398539ccb6d0e4 1001 Pfam PF00586 AIR synthase related protein, N-terminal domain 695 810 2.3E-4 T 22-04-2016 IPR016188 PurM-like, N-terminal domain L21SP4_RS08935 293629a04c70cc4c17398539ccb6d0e4 1001 SUPERFAMILY SSF55326 627 819 6.28E-44 T 22-04-2016 L21SP4_RS08935 293629a04c70cc4c17398539ccb6d0e4 1001 SUPERFAMILY SSF56042 822 998 5.98E-30 T 22-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain L21SP4_RS08935 293629a04c70cc4c17398539ccb6d0e4 1001 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 187 1001 179.208 T 22-04-2016 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 L21SP4_RS08935 293629a04c70cc4c17398539ccb6d0e4 1001 PANTHER PTHR10099 6 999 1.1E-304 T 22-04-2016 L21SP4_RS08935 293629a04c70cc4c17398539ccb6d0e4 1001 Gene3D G3DSA:3.30.1330.10 646 815 1.9E-33 T 22-04-2016 IPR016188 PurM-like, N-terminal domain L21SP4_RS08935 293629a04c70cc4c17398539ccb6d0e4 1001 Pfam PF02769 AIR synthase related protein, C-terminal domain 439 591 2.4E-19 T 22-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain L21SP4_RS08935 293629a04c70cc4c17398539ccb6d0e4 1001 Pfam PF02769 AIR synthase related protein, C-terminal domain 824 975 2.6E-12 T 22-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain L21SP4_RS08935 293629a04c70cc4c17398539ccb6d0e4 1001 PANTHER PTHR10099:SF2 6 999 1.1E-304 T 22-04-2016 L21SP4_RS08935 293629a04c70cc4c17398539ccb6d0e4 1001 Gene3D G3DSA:3.30.1330.10 244 259 1.8E-27 T 22-04-2016 IPR016188 PurM-like, N-terminal domain L21SP4_RS08935 293629a04c70cc4c17398539ccb6d0e4 1001 Gene3D G3DSA:3.30.1330.10 291 425 1.8E-27 T 22-04-2016 IPR016188 PurM-like, N-terminal domain L21SP4_RS08935 293629a04c70cc4c17398539ccb6d0e4 1001 SUPERFAMILY SSF55326 229 255 1.4E-34 T 22-04-2016 L21SP4_RS08935 293629a04c70cc4c17398539ccb6d0e4 1001 SUPERFAMILY SSF55326 290 425 1.4E-34 T 22-04-2016 L21SP4_RS11305 01580c5e60e3e5bc7374e161eb248a99 318 PRINTS PR01713 Nucleotide sugar epimerase signature 235 250 2.5E-6 T 22-04-2016 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 L21SP4_RS11305 01580c5e60e3e5bc7374e161eb248a99 318 PRINTS PR01713 Nucleotide sugar epimerase signature 211 226 2.5E-6 T 22-04-2016 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 L21SP4_RS11305 01580c5e60e3e5bc7374e161eb248a99 318 PRINTS PR01713 Nucleotide sugar epimerase signature 274 291 2.5E-6 T 22-04-2016 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 L21SP4_RS11305 01580c5e60e3e5bc7374e161eb248a99 318 SUPERFAMILY SSF51735 1 309 2.36E-94 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS11305 01580c5e60e3e5bc7374e161eb248a99 318 PANTHER PTHR10366:SF466 3 305 1.6E-96 T 22-04-2016 L21SP4_RS11305 01580c5e60e3e5bc7374e161eb248a99 318 Pfam PF01370 NAD dependent epimerase/dehydratase family 5 241 1.9E-63 T 22-04-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 L21SP4_RS11305 01580c5e60e3e5bc7374e161eb248a99 318 Gene3D G3DSA:3.40.50.720 1 174 3.9E-55 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS11305 01580c5e60e3e5bc7374e161eb248a99 318 PANTHER PTHR10366 3 305 1.6E-96 T 22-04-2016 L21SP4_RS11305 01580c5e60e3e5bc7374e161eb248a99 318 Gene3D G3DSA:3.90.25.10 175 297 1.1E-32 T 22-04-2016 L21SP4_RS02195 76457945dfb3867f3c96b9ec2f5d28b8 494 Gene3D G3DSA:1.10.150.20 435 487 1.0E-18 T 22-04-2016 L21SP4_RS02195 76457945dfb3867f3c96b9ec2f5d28b8 494 SUPERFAMILY SSF47781 400 488 7.79E-21 T 22-04-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 L21SP4_RS02195 76457945dfb3867f3c96b9ec2f5d28b8 494 SMART SM00278 435 454 7.4 T 22-04-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 L21SP4_RS02195 76457945dfb3867f3c96b9ec2f5d28b8 494 SMART SM00278 467 486 38.0 T 22-04-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 L21SP4_RS02195 76457945dfb3867f3c96b9ec2f5d28b8 494 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 271 421 1.7E-43 T 22-04-2016 IPR001162 UvrC family homology region L21SP4_RS02195 76457945dfb3867f3c96b9ec2f5d28b8 494 Pfam PF02151 UvrB/uvrC motif 209 238 1.9E-7 T 22-04-2016 IPR001943 UVR domain GO:0005515 L21SP4_RS02195 76457945dfb3867f3c96b9ec2f5d28b8 494 Gene3D G3DSA:3.40.1440.10 18 98 1.0E-8 T 22-04-2016 IPR027299 GIY-YIG domain L21SP4_RS02195 76457945dfb3867f3c96b9ec2f5d28b8 494 Pfam PF14520 Helix-hairpin-helix domain 437 488 3.6E-11 T 22-04-2016 L21SP4_RS02195 76457945dfb3867f3c96b9ec2f5d28b8 494 SUPERFAMILY SSF46600 195 242 5.89E-9 T 22-04-2016 IPR001943 UVR domain GO:0005515 L21SP4_RS02195 76457945dfb3867f3c96b9ec2f5d28b8 494 PANTHER PTHR30562 1 487 1.0E-163 T 22-04-2016 L21SP4_RS02195 76457945dfb3867f3c96b9ec2f5d28b8 494 Pfam PF01541 GIY-YIG catalytic domain 19 96 1.1E-7 T 22-04-2016 IPR000305 GIY-YIG nuclease superfamily L21SP4_RS02195 76457945dfb3867f3c96b9ec2f5d28b8 494 SMART SM00465 17 101 2.5E-18 T 22-04-2016 IPR000305 GIY-YIG nuclease superfamily L21SP4_RS02195 76457945dfb3867f3c96b9ec2f5d28b8 494 Gene3D G3DSA:4.10.860.10 187 240 5.1E-13 T 22-04-2016 IPR001943 UVR domain GO:0005515 L21SP4_RS02195 76457945dfb3867f3c96b9ec2f5d28b8 494 PANTHER PTHR30562:SF1 1 487 1.0E-163 T 22-04-2016 L21SP4_RS02195 76457945dfb3867f3c96b9ec2f5d28b8 494 SUPERFAMILY SSF82771 17 103 1.83E-19 T 22-04-2016 IPR000305 GIY-YIG nuclease superfamily L21SP4_RS07420 b9aef224e66bf4bfd52c212b53ab87b4 631 ProSitePatterns PS00505 Phosphoenolpyruvate carboxykinase (GTP) signature. 275 283 - T 22-04-2016 IPR018091 Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site GO:0004613 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00138 L21SP4_RS07420 b9aef224e66bf4bfd52c212b53ab87b4 631 SUPERFAMILY SSF53795 250 613 7.55E-96 T 22-04-2016 L21SP4_RS07420 b9aef224e66bf4bfd52c212b53ab87b4 631 Gene3D G3DSA:2.170.8.10 303 399 1.8E-18 T 22-04-2016 L21SP4_RS07420 b9aef224e66bf4bfd52c212b53ab87b4 631 SUPERFAMILY SSF68923 15 249 4.29E-46 T 22-04-2016 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: REACT_474|UniPathway: UPA00138 L21SP4_RS07420 b9aef224e66bf4bfd52c212b53ab87b4 631 Hamap MF_00452 Phosphoenolpyruvate carboxykinase [GTP] [pckG]. 20 614 29.666 T 22-04-2016 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00138 L21SP4_RS07420 b9aef224e66bf4bfd52c212b53ab87b4 631 Gene3D G3DSA:3.40.449.10 16 249 3.2E-47 T 22-04-2016 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: REACT_474|UniPathway: UPA00138 L21SP4_RS07420 b9aef224e66bf4bfd52c212b53ab87b4 631 Gene3D G3DSA:3.90.228.20 404 613 3.3E-67 T 22-04-2016 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: REACT_474|UniPathway: UPA00138 L21SP4_RS07420 b9aef224e66bf4bfd52c212b53ab87b4 631 Gene3D G3DSA:3.90.228.20 250 302 3.3E-67 T 22-04-2016 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: REACT_474|UniPathway: UPA00138 L21SP4_RS07420 b9aef224e66bf4bfd52c212b53ab87b4 631 PANTHER PTHR11561 7 627 5.8E-168 T 22-04-2016 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00138 L21SP4_RS07420 b9aef224e66bf4bfd52c212b53ab87b4 631 PIRSF PIRSF001348 7 617 2.7E-162 T 22-04-2016 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00138 L21SP4_RS07420 b9aef224e66bf4bfd52c212b53ab87b4 631 Pfam PF00821 Phosphoenolpyruvate carboxykinase 32 609 3.5E-157 T 22-04-2016 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00138 L21SP4_RS07420 b9aef224e66bf4bfd52c212b53ab87b4 631 PANTHER PTHR11561:SF0 7 627 5.8E-168 T 22-04-2016 L21SP4_RS00145 c3fa5e9b99c0dad694acb50c5f2ac9ff 220 PIRSF PIRSF003078 3 205 5.3E-44 T 22-04-2016 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 L21SP4_RS00145 c3fa5e9b99c0dad694acb50c5f2ac9ff 220 SUPERFAMILY SSF53335 9 152 2.48E-26 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS00145 c3fa5e9b99c0dad694acb50c5f2ac9ff 220 Gene3D G3DSA:3.40.50.150 8 182 4.5E-45 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS00145 c3fa5e9b99c0dad694acb50c5f2ac9ff 220 PANTHER PTHR31760:SF0 7 182 1.4E-41 T 22-04-2016 L21SP4_RS00145 c3fa5e9b99c0dad694acb50c5f2ac9ff 220 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 12 209 23.284 T 22-04-2016 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 L21SP4_RS00145 c3fa5e9b99c0dad694acb50c5f2ac9ff 220 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 24 151 1.9E-33 T 22-04-2016 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 L21SP4_RS00145 c3fa5e9b99c0dad694acb50c5f2ac9ff 220 Pfam PF02527 rRNA small subunit methyltransferase G 22 152 3.8E-37 T 22-04-2016 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 L21SP4_RS00145 c3fa5e9b99c0dad694acb50c5f2ac9ff 220 PANTHER PTHR31760 7 182 1.4E-41 T 22-04-2016 L21SP4_RS08415 26ab4b33178ae4197b01373534cd9ba7 708 PANTHER PTHR23115:SF66 5 195 4.0E-298 T 22-04-2016 L21SP4_RS08415 26ab4b33178ae4197b01373534cd9ba7 708 PANTHER PTHR23115 321 708 4.0E-298 T 22-04-2016 L21SP4_RS08415 26ab4b33178ae4197b01373534cd9ba7 708 SUPERFAMILY SSF54980 422 499 8.63E-24 T 22-04-2016 IPR009022 Elongation factor G, III-V domain L21SP4_RS08415 26ab4b33178ae4197b01373534cd9ba7 708 Gene3D G3DSA:2.40.30.10 326 423 9.9E-36 T 22-04-2016 L21SP4_RS08415 26ab4b33178ae4197b01373534cd9ba7 708 PANTHER PTHR23115 273 301 4.0E-298 T 22-04-2016 L21SP4_RS08415 26ab4b33178ae4197b01373534cd9ba7 708 Gene3D G3DSA:3.30.70.240 616 705 2.0E-28 T 22-04-2016 IPR000640 Translation elongation factor EFG, V domain L21SP4_RS08415 26ab4b33178ae4197b01373534cd9ba7 708 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 29 198 4.4E-31 T 22-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 L21SP4_RS08415 26ab4b33178ae4197b01373534cd9ba7 708 Pfam PF00009 Elongation factor Tu GTP binding domain 28 300 4.4E-67 T 22-04-2016 L21SP4_RS08415 26ab4b33178ae4197b01373534cd9ba7 708 Gene3D G3DSA:3.30.230.10 502 615 2.2E-29 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup L21SP4_RS08415 26ab4b33178ae4197b01373534cd9ba7 708 SMART SM00838 618 705 1.3E-46 T 22-04-2016 IPR000640 Translation elongation factor EFG, V domain L21SP4_RS08415 26ab4b33178ae4197b01373534cd9ba7 708 SMART SM00889 498 616 7.9E-30 T 22-04-2016 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 L21SP4_RS08415 26ab4b33178ae4197b01373534cd9ba7 708 SUPERFAMILY SSF50447 284 420 1.19E-34 T 22-04-2016 IPR009000 Translation protein, beta-barrel domain L21SP4_RS08415 26ab4b33178ae4197b01373534cd9ba7 708 PRINTS PR00315 GTP-binding elongation factor signature 76 84 1.1E-15 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 L21SP4_RS08415 26ab4b33178ae4197b01373534cd9ba7 708 PRINTS PR00315 GTP-binding elongation factor signature 112 123 1.1E-15 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 L21SP4_RS08415 26ab4b33178ae4197b01373534cd9ba7 708 PRINTS PR00315 GTP-binding elongation factor signature 96 106 1.1E-15 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 L21SP4_RS08415 26ab4b33178ae4197b01373534cd9ba7 708 PRINTS PR00315 GTP-binding elongation factor signature 30 43 1.1E-15 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 L21SP4_RS08415 26ab4b33178ae4197b01373534cd9ba7 708 PRINTS PR00315 GTP-binding elongation factor signature 148 157 1.1E-15 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 L21SP4_RS08415 26ab4b33178ae4197b01373534cd9ba7 708 TIGRFAM TIGR00484 EF-G: translation elongation factor G 22 707 2.8E-278 T 22-04-2016 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 L21SP4_RS08415 26ab4b33178ae4197b01373534cd9ba7 708 SUPERFAMILY SSF54211 497 617 1.29E-26 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold L21SP4_RS08415 26ab4b33178ae4197b01373534cd9ba7 708 PANTHER PTHR23115:SF66 321 708 4.0E-298 T 22-04-2016 L21SP4_RS08415 26ab4b33178ae4197b01373534cd9ba7 708 Pfam PF03764 Elongation factor G, domain IV 497 615 1.0E-23 T 22-04-2016 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 L21SP4_RS08415 26ab4b33178ae4197b01373534cd9ba7 708 SUPERFAMILY SSF54980 618 706 6.83E-26 T 22-04-2016 IPR009022 Elongation factor G, III-V domain L21SP4_RS08415 26ab4b33178ae4197b01373534cd9ba7 708 Pfam PF00679 Elongation factor G C-terminus 618 704 2.7E-26 T 22-04-2016 IPR000640 Translation elongation factor EFG, V domain L21SP4_RS08415 26ab4b33178ae4197b01373534cd9ba7 708 PANTHER PTHR23115 5 195 4.0E-298 T 22-04-2016 L21SP4_RS08415 26ab4b33178ae4197b01373534cd9ba7 708 Gene3D G3DSA:3.30.70.870 424 497 1.6E-33 T 22-04-2016 L21SP4_RS08415 26ab4b33178ae4197b01373534cd9ba7 708 Gene3D G3DSA:3.40.50.300 27 305 5.2E-101 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS08415 26ab4b33178ae4197b01373534cd9ba7 708 Pfam PF14492 Elongation Factor G, domain II 422 495 2.0E-32 T 22-04-2016 IPR009022 Elongation factor G, III-V domain L21SP4_RS08415 26ab4b33178ae4197b01373534cd9ba7 708 PANTHER PTHR23115:SF66 273 301 4.0E-298 T 22-04-2016 L21SP4_RS08415 26ab4b33178ae4197b01373534cd9ba7 708 Hamap MF_00054_B Elongation factor G [fusA]. 24 708 96.726 T 22-04-2016 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 L21SP4_RS08415 26ab4b33178ae4197b01373534cd9ba7 708 Pfam PF03144 Elongation factor Tu domain 2 342 409 1.2E-16 T 22-04-2016 IPR004161 Translation elongation factor EFTu/EF1A, domain 2 GO:0005525 L21SP4_RS08415 26ab4b33178ae4197b01373534cd9ba7 708 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 69 84 - T 22-04-2016 IPR031157 Tr-type G domain, conserved site L21SP4_RS08415 26ab4b33178ae4197b01373534cd9ba7 708 SUPERFAMILY SSF52540 26 300 6.14E-102 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS06305 587ea67b030c430fdf2db2d3975bb8a3 336 SUPERFAMILY SSF51726 5 327 3.66E-56 T 22-04-2016 L21SP4_RS06305 587ea67b030c430fdf2db2d3975bb8a3 336 Gene3D G3DSA:3.20.20.210 1 327 6.6E-66 T 22-04-2016 L21SP4_RS06305 587ea67b030c430fdf2db2d3975bb8a3 336 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 3 327 1.0E-62 T 22-04-2016 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 L21SP4_RS06305 587ea67b030c430fdf2db2d3975bb8a3 336 PANTHER PTHR21091 96 327 5.1E-21 T 22-04-2016 L21SP4_RS06305 587ea67b030c430fdf2db2d3975bb8a3 336 PANTHER PTHR21091:SF2 96 327 5.1E-21 T 22-04-2016 L21SP4_RS08765 9c52b3d9772a49682e9ba4a5b8a62313 460 PANTHER PTHR11911:SF23 102 415 3.4E-39 T 22-04-2016 L21SP4_RS08765 9c52b3d9772a49682e9ba4a5b8a62313 460 SMART SM00924 30 132 2.0E-27 T 22-04-2016 IPR006668 Magnesium transporter, MgtE intracellular domain L21SP4_RS08765 9c52b3d9772a49682e9ba4a5b8a62313 460 PANTHER PTHR11911 102 415 3.4E-39 T 22-04-2016 L21SP4_RS08765 9c52b3d9772a49682e9ba4a5b8a62313 460 TIGRFAM TIGR00400 mgtE: magnesium transporter 16 456 8.5E-100 T 22-04-2016 IPR006669 Magnesium transporter MgtE GO:0015095|GO:0015693|GO:0016020 L21SP4_RS08765 9c52b3d9772a49682e9ba4a5b8a62313 460 Gene3D G3DSA:1.10.357.20 273 456 6.3E-42 T 22-04-2016 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 L21SP4_RS08765 9c52b3d9772a49682e9ba4a5b8a62313 460 Gene3D G3DSA:1.25.60.10 10 124 8.7E-27 T 22-04-2016 L21SP4_RS08765 9c52b3d9772a49682e9ba4a5b8a62313 460 SUPERFAMILY SSF161093 273 456 6.54E-40 T 22-04-2016 L21SP4_RS08765 9c52b3d9772a49682e9ba4a5b8a62313 460 SUPERFAMILY SSF158791 13 129 2.09E-23 T 22-04-2016 L21SP4_RS08765 9c52b3d9772a49682e9ba4a5b8a62313 460 Gene3D G3DSA:3.10.580.10 125 256 1.6E-23 T 22-04-2016 L21SP4_RS08765 9c52b3d9772a49682e9ba4a5b8a62313 460 Pfam PF03448 MgtE intracellular N domain 30 130 1.7E-21 T 22-04-2016 IPR006668 Magnesium transporter, MgtE intracellular domain L21SP4_RS08765 9c52b3d9772a49682e9ba4a5b8a62313 460 Pfam PF01769 Divalent cation transporter 318 450 1.2E-25 T 22-04-2016 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 L21SP4_RS08765 9c52b3d9772a49682e9ba4a5b8a62313 460 Pfam PF00571 CBS domain 133 188 1.6E-5 T 22-04-2016 IPR000644 CBS domain L21SP4_RS08765 9c52b3d9772a49682e9ba4a5b8a62313 460 Pfam PF00571 CBS domain 198 251 3.1E-7 T 22-04-2016 IPR000644 CBS domain L21SP4_RS08765 9c52b3d9772a49682e9ba4a5b8a62313 460 SMART SM00116 203 251 2.1E-4 T 22-04-2016 IPR000644 CBS domain L21SP4_RS08765 9c52b3d9772a49682e9ba4a5b8a62313 460 SMART SM00116 139 191 27.0 T 22-04-2016 IPR000644 CBS domain L21SP4_RS08765 9c52b3d9772a49682e9ba4a5b8a62313 460 SUPERFAMILY SSF54631 131 264 2.4E-29 T 22-04-2016 L21SP4_RS01685 dd5d795aa413efc61e51b6fcfa60eaa4 280 PANTHER PTHR11741 3 278 2.0E-93 T 22-04-2016 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 L21SP4_RS01685 dd5d795aa413efc61e51b6fcfa60eaa4 280 SUPERFAMILY SSF46934 3 55 1.4E-16 T 22-04-2016 IPR009060 UBA-like GO:0005515 L21SP4_RS01685 dd5d795aa413efc61e51b6fcfa60eaa4 280 SUPERFAMILY SSF54713 142 278 2.22E-37 T 22-04-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 L21SP4_RS01685 dd5d795aa413efc61e51b6fcfa60eaa4 280 Gene3D G3DSA:1.10.8.10 3 55 6.6E-22 T 22-04-2016 L21SP4_RS01685 dd5d795aa413efc61e51b6fcfa60eaa4 280 SUPERFAMILY SSF54713 57 139 9.81E-17 T 22-04-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 L21SP4_RS01685 dd5d795aa413efc61e51b6fcfa60eaa4 280 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 278 2.4E-78 T 22-04-2016 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 L21SP4_RS01685 dd5d795aa413efc61e51b6fcfa60eaa4 280 Gene3D G3DSA:3.30.479.20 57 110 7.1E-14 T 22-04-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 L21SP4_RS01685 dd5d795aa413efc61e51b6fcfa60eaa4 280 Gene3D G3DSA:3.30.479.20 145 190 2.2E-19 T 22-04-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 L21SP4_RS01685 dd5d795aa413efc61e51b6fcfa60eaa4 280 Gene3D G3DSA:3.30.479.20 237 278 2.2E-19 T 22-04-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 L21SP4_RS01685 dd5d795aa413efc61e51b6fcfa60eaa4 280 Hamap MF_00050 Elongation factor Ts [tsf]. 1 280 59.722 T 22-04-2016 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 L21SP4_RS01685 dd5d795aa413efc61e51b6fcfa60eaa4 280 Pfam PF00889 Elongation factor TS 73 278 1.4E-58 T 22-04-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 L21SP4_RS01685 dd5d795aa413efc61e51b6fcfa60eaa4 280 Gene3D G3DSA:1.10.286.20 195 236 9.9E-16 T 22-04-2016 L21SP4_RS01685 dd5d795aa413efc61e51b6fcfa60eaa4 280 ProSitePatterns PS01127 Elongation factor Ts signature 2. 77 87 - T 22-04-2016 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 L21SP4_RS03865 b1c527ed60c9e335c50403352347cae3 593 SUPERFAMILY SSF52009 137 258 4.71E-34 T 22-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 L21SP4_RS03865 b1c527ed60c9e335c50403352347cae3 593 PANTHER PTHR22931:SF28 41 562 2.6E-178 T 22-04-2016 L21SP4_RS03865 b1c527ed60c9e335c50403352347cae3 593 PIRSF PIRSF000732 9 585 3.9E-215 T 22-04-2016 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 L21SP4_RS03865 b1c527ed60c9e335c50403352347cae3 593 SUPERFAMILY SSF47831 37 155 2.88E-30 T 22-04-2016 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 L21SP4_RS03865 b1c527ed60c9e335c50403352347cae3 593 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 14 570 3.2E-186 T 22-04-2016 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 L21SP4_RS03865 b1c527ed60c9e335c50403352347cae3 593 SUPERFAMILY SSF51621 265 554 4.85E-101 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 L21SP4_RS03865 b1c527ed60c9e335c50403352347cae3 593 Gene3D G3DSA:1.10.274.10 36 144 2.6E-33 T 22-04-2016 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 L21SP4_RS03865 b1c527ed60c9e335c50403352347cae3 593 Gene3D G3DSA:3.50.30.10 145 267 1.5E-38 T 22-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 L21SP4_RS03865 b1c527ed60c9e335c50403352347cae3 593 Gene3D G3DSA:3.20.20.60 268 582 3.6E-105 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 L21SP4_RS03865 b1c527ed60c9e335c50403352347cae3 593 Pfam PF05524 PEP-utilising enzyme, N-terminal 15 138 2.6E-27 T 22-04-2016 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 L21SP4_RS03865 b1c527ed60c9e335c50403352347cae3 593 PANTHER PTHR22931 41 562 2.6E-178 T 22-04-2016 L21SP4_RS03865 b1c527ed60c9e335c50403352347cae3 593 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 305 324 9.6E-24 T 22-04-2016 L21SP4_RS03865 b1c527ed60c9e335c50403352347cae3 593 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 459 474 9.6E-24 T 22-04-2016 L21SP4_RS03865 b1c527ed60c9e335c50403352347cae3 593 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 512 524 9.6E-24 T 22-04-2016 L21SP4_RS03865 b1c527ed60c9e335c50403352347cae3 593 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 476 491 9.6E-24 T 22-04-2016 L21SP4_RS03865 b1c527ed60c9e335c50403352347cae3 593 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 459 477 - T 22-04-2016 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 L21SP4_RS03865 b1c527ed60c9e335c50403352347cae3 593 Pfam PF00391 PEP-utilising enzyme, mobile domain 164 237 9.8E-22 T 22-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 L21SP4_RS03865 b1c527ed60c9e335c50403352347cae3 593 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 264 553 1.6E-105 T 22-04-2016 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 L21SP4_RS08325 9289e685f1ce69948dac77216a314e5c 114 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 5 114 22.506 T 22-04-2016 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS08325 9289e685f1ce69948dac77216a314e5c 114 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 6 114 8.1E-29 T 22-04-2016 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS08325 9289e685f1ce69948dac77216a314e5c 114 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 5 114 2.6E-32 T 22-04-2016 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS08325 9289e685f1ce69948dac77216a314e5c 114 Gene3D G3DSA:3.30.420.100 23 114 1.2E-26 T 22-04-2016 L21SP4_RS08325 9289e685f1ce69948dac77216a314e5c 114 SUPERFAMILY SSF53137 6 112 6.54E-36 T 22-04-2016 L21SP4_RS08325 9289e685f1ce69948dac77216a314e5c 114 PANTHER PTHR12899 1 114 6.2E-27 T 22-04-2016 L21SP4_RS02365 d36e833e396842f24d3af6b0c12b2c49 259 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 18 191 1.2E-43 T 22-04-2016 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380|UniPathway: UPA00078 L21SP4_RS02365 d36e833e396842f24d3af6b0c12b2c49 259 Pfam PF13500 AAA domain 16 228 9.8E-41 T 22-04-2016 L21SP4_RS02365 d36e833e396842f24d3af6b0c12b2c49 259 Gene3D G3DSA:3.40.50.300 16 228 1.8E-69 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS02365 d36e833e396842f24d3af6b0c12b2c49 259 SUPERFAMILY SSF52540 16 228 1.06E-50 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS02365 d36e833e396842f24d3af6b0c12b2c49 259 PANTHER PTHR21343:SF0 16 228 1.3E-60 T 22-04-2016 L21SP4_RS02365 d36e833e396842f24d3af6b0c12b2c49 259 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 14 226 27.332 T 22-04-2016 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380|UniPathway: UPA00078 L21SP4_RS02365 d36e833e396842f24d3af6b0c12b2c49 259 PIRSF PIRSF006755 14 235 2.8E-55 T 22-04-2016 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380|UniPathway: UPA00078 L21SP4_RS02365 d36e833e396842f24d3af6b0c12b2c49 259 PANTHER PTHR21343 16 228 1.3E-60 T 22-04-2016 L21SP4_RS03985 55150de907154562d56a8fda91b671cd 198 PANTHER PTHR30390 1 191 6.8E-65 T 22-04-2016 L21SP4_RS03985 55150de907154562d56a8fda91b671cd 198 PANTHER PTHR30390:SF6 1 191 6.8E-65 T 22-04-2016 L21SP4_RS03985 55150de907154562d56a8fda91b671cd 198 Pfam PF13580 SIS domain 23 142 5.7E-29 T 22-04-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 Reactome: REACT_17015 L21SP4_RS03985 55150de907154562d56a8fda91b671cd 198 Gene3D G3DSA:3.40.50.10490 21 186 1.1E-51 T 22-04-2016 L21SP4_RS03985 55150de907154562d56a8fda91b671cd 198 SUPERFAMILY SSF53697 13 186 3.24E-47 T 22-04-2016 L21SP4_RS11125 28541afe279885e0e5011ff71bf2aed1 202 PANTHER PTHR12725:SF63 1 181 2.1E-28 T 22-04-2016 L21SP4_RS11125 28541afe279885e0e5011ff71bf2aed1 202 Gene3D G3DSA:1.10.150.240 32 78 4.2E-10 T 22-04-2016 IPR023198 Phosphoglycolate phosphatase, domain 2 L21SP4_RS11125 28541afe279885e0e5011ff71bf2aed1 202 PANTHER PTHR12725 1 181 2.1E-28 T 22-04-2016 L21SP4_RS11125 28541afe279885e0e5011ff71bf2aed1 202 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 133 182 7.8E-9 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 L21SP4_RS11125 28541afe279885e0e5011ff71bf2aed1 202 SUPERFAMILY SSF56784 5 188 7.35E-34 T 22-04-2016 IPR023214 HAD-like domain L21SP4_RS11125 28541afe279885e0e5011ff71bf2aed1 202 Pfam PF13419 Haloacid dehalogenase-like hydrolase 82 182 5.5E-8 T 22-04-2016 IPR023214 HAD-like domain L21SP4_RS11125 28541afe279885e0e5011ff71bf2aed1 202 Gene3D G3DSA:3.40.50.1000 79 187 1.1E-25 T 22-04-2016 IPR023214 HAD-like domain L21SP4_RS11125 28541afe279885e0e5011ff71bf2aed1 202 Gene3D G3DSA:3.40.50.1000 2 20 1.1E-25 T 22-04-2016 IPR023214 HAD-like domain L21SP4_RS01280 67941595c5108591d9fa88e0bb257b04 1094 Pfam PF08448 PAS fold 347 462 2.8E-17 T 22-04-2016 IPR013656 PAS fold-4 L21SP4_RS01280 67941595c5108591d9fa88e0bb257b04 1094 Pfam PF00072 Response regulator receiver domain 977 1088 2.7E-18 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 L21SP4_RS01280 67941595c5108591d9fa88e0bb257b04 1094 Gene3D G3DSA:3.40.50.2300 974 1093 4.8E-30 T 22-04-2016 L21SP4_RS01280 67941595c5108591d9fa88e0bb257b04 1094 SMART SM00387 832 955 1.7E-25 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS01280 67941595c5108591d9fa88e0bb257b04 1094 Pfam PF13188 PAS domain 472 519 1.6E-7 T 22-04-2016 IPR000014 PAS domain L21SP4_RS01280 67941595c5108591d9fa88e0bb257b04 1094 SMART SM00388 725 791 8.7E-8 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS01280 67941595c5108591d9fa88e0bb257b04 1094 PANTHER PTHR24423:SF458 24 475 6.4E-180 T 22-04-2016 L21SP4_RS01280 67941595c5108591d9fa88e0bb257b04 1094 PANTHER PTHR24423:SF458 594 1094 6.4E-180 T 22-04-2016 L21SP4_RS01280 67941595c5108591d9fa88e0bb257b04 1094 PRINTS PR00344 Bacterial sensor protein C-terminal signature 939 952 2.2E-14 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS01280 67941595c5108591d9fa88e0bb257b04 1094 PRINTS PR00344 Bacterial sensor protein C-terminal signature 884 898 2.2E-14 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS01280 67941595c5108591d9fa88e0bb257b04 1094 PRINTS PR00344 Bacterial sensor protein C-terminal signature 915 933 2.2E-14 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS01280 67941595c5108591d9fa88e0bb257b04 1094 PRINTS PR00344 Bacterial sensor protein C-terminal signature 902 912 2.2E-14 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS01280 67941595c5108591d9fa88e0bb257b04 1094 Pfam PF00512 His Kinase A (phospho-acceptor) domain 726 789 7.6E-8 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS01280 67941595c5108591d9fa88e0bb257b04 1094 SUPERFAMILY SSF52172 975 1093 4.13E-28 T 22-04-2016 IPR011006 CheY-like superfamily L21SP4_RS01280 67941595c5108591d9fa88e0bb257b04 1094 SMART SM00448 975 1088 1.6E-18 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 L21SP4_RS01280 67941595c5108591d9fa88e0bb257b04 1094 SMART SM00091 472 543 1.4E-5 T 22-04-2016 IPR000014 PAS domain L21SP4_RS01280 67941595c5108591d9fa88e0bb257b04 1094 SMART SM00091 596 662 1.8E-5 T 22-04-2016 IPR000014 PAS domain L21SP4_RS01280 67941595c5108591d9fa88e0bb257b04 1094 SMART SM00091 341 410 1.0E-9 T 22-04-2016 IPR000014 PAS domain L21SP4_RS01280 67941595c5108591d9fa88e0bb257b04 1094 SMART SM00086 418 460 0.044 T 22-04-2016 IPR001610 PAC motif L21SP4_RS01280 67941595c5108591d9fa88e0bb257b04 1094 SMART SM00086 668 710 1.5E-6 T 22-04-2016 IPR001610 PAC motif L21SP4_RS01280 67941595c5108591d9fa88e0bb257b04 1094 SUPERFAMILY SSF47384 716 788 5.69E-10 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS01280 67941595c5108591d9fa88e0bb257b04 1094 SUPERFAMILY SSF55785 458 586 9.07E-18 T 22-04-2016 IPR000014 PAS domain L21SP4_RS01280 67941595c5108591d9fa88e0bb257b04 1094 PANTHER PTHR24423 24 475 6.4E-180 T 22-04-2016 L21SP4_RS01280 67941595c5108591d9fa88e0bb257b04 1094 PANTHER PTHR24423 594 1094 6.4E-180 T 22-04-2016 L21SP4_RS01280 67941595c5108591d9fa88e0bb257b04 1094 Gene3D G3DSA:3.30.450.20 586 703 1.9E-28 T 22-04-2016 L21SP4_RS01280 67941595c5108591d9fa88e0bb257b04 1094 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 468 595 1.2E-12 T 22-04-2016 IPR000014 PAS domain L21SP4_RS01280 67941595c5108591d9fa88e0bb257b04 1094 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 594 715 1.0E-21 T 22-04-2016 IPR000014 PAS domain L21SP4_RS01280 67941595c5108591d9fa88e0bb257b04 1094 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 337 467 8.2E-20 T 22-04-2016 IPR000014 PAS domain L21SP4_RS01280 67941595c5108591d9fa88e0bb257b04 1094 SUPERFAMILY SSF55785 329 456 9.6E-24 T 22-04-2016 IPR000014 PAS domain L21SP4_RS01280 67941595c5108591d9fa88e0bb257b04 1094 Pfam PF13426 PAS domain 607 708 2.7E-14 T 22-04-2016 IPR000014 PAS domain L21SP4_RS01280 67941595c5108591d9fa88e0bb257b04 1094 SUPERFAMILY SSF55785 602 708 5.93E-29 T 22-04-2016 IPR000014 PAS domain L21SP4_RS01280 67941595c5108591d9fa88e0bb257b04 1094 Gene3D G3DSA:3.30.450.20 458 585 6.8E-20 T 22-04-2016 L21SP4_RS01280 67941595c5108591d9fa88e0bb257b04 1094 Gene3D G3DSA:3.30.450.20 329 456 7.4E-26 T 22-04-2016 L21SP4_RS01280 67941595c5108591d9fa88e0bb257b04 1094 SUPERFAMILY SSF55874 781 957 3.54E-38 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS01280 67941595c5108591d9fa88e0bb257b04 1094 Gene3D G3DSA:3.30.565.10 777 955 4.7E-36 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS01280 67941595c5108591d9fa88e0bb257b04 1094 Gene3D G3DSA:1.10.287.130 718 776 5.1E-6 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS01280 67941595c5108591d9fa88e0bb257b04 1094 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 833 952 6.1E-18 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS01725 d663e0d87d71fbbc03279fd004914f4e 434 SMART SM00670 3 129 3.3E-12 T 22-04-2016 IPR002716 PIN domain L21SP4_RS01725 d663e0d87d71fbbc03279fd004914f4e 434 SUPERFAMILY SSF88723 2 64 2.94E-15 T 22-04-2016 IPR029060 PIN domain-like L21SP4_RS01725 d663e0d87d71fbbc03279fd004914f4e 434 SUPERFAMILY SSF88723 92 142 2.94E-15 T 22-04-2016 IPR029060 PIN domain-like L21SP4_RS01725 d663e0d87d71fbbc03279fd004914f4e 434 PANTHER PTHR30473 2 434 5.3E-169 T 22-04-2016 L21SP4_RS01725 d663e0d87d71fbbc03279fd004914f4e 434 Pfam PF13638 PIN domain 5 142 2.8E-31 T 22-04-2016 IPR002716 PIN domain L21SP4_RS01725 d663e0d87d71fbbc03279fd004914f4e 434 SUPERFAMILY SSF52540 225 409 2.96E-27 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS01725 d663e0d87d71fbbc03279fd004914f4e 434 SUPERFAMILY SSF52540 118 175 2.96E-27 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS01725 d663e0d87d71fbbc03279fd004914f4e 434 Gene3D G3DSA:3.40.50.300 225 433 6.4E-60 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS01725 d663e0d87d71fbbc03279fd004914f4e 434 PANTHER PTHR30473:SF2 2 434 5.3E-169 T 22-04-2016 L21SP4_RS01725 d663e0d87d71fbbc03279fd004914f4e 434 Gene3D G3DSA:3.40.50.1010 3 143 1.5E-16 T 22-04-2016 IPR029060 PIN domain-like L21SP4_RS01725 d663e0d87d71fbbc03279fd004914f4e 434 Pfam PF02562 PhoH-like protein 226 430 1.5E-54 T 22-04-2016 IPR003714 PhoH-like protein GO:0005524 L21SP4_RS03675 eaa57063f8358150f41ca0ff9850a517 154 Gene3D G3DSA:3.90.1010.10 40 142 4.4E-17 T 22-04-2016 L21SP4_RS03675 eaa57063f8358150f41ca0ff9850a517 154 SUPERFAMILY SSF82649 40 141 2.17E-20 T 22-04-2016 L21SP4_RS03675 eaa57063f8358150f41ca0ff9850a517 154 Pfam PF01592 NifU-like N terminal domain 50 141 1.6E-14 T 22-04-2016 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 L21SP4_RS01915 dbd856d0d2c07b2bd99f37f65603f385 255 Gene3D G3DSA:1.10.10.10 2 57 2.3E-10 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS01915 dbd856d0d2c07b2bd99f37f65603f385 255 Gene3D G3DSA:3.40.50.1360 75 216 3.2E-16 T 22-04-2016 L21SP4_RS01915 dbd856d0d2c07b2bd99f37f65603f385 255 SMART SM01134 73 234 1.7E-53 T 22-04-2016 L21SP4_RS01915 dbd856d0d2c07b2bd99f37f65603f385 255 SUPERFAMILY SSF100950 75 233 8.06E-29 T 22-04-2016 L21SP4_RS01915 dbd856d0d2c07b2bd99f37f65603f385 255 PANTHER PTHR30363:SF1 1 254 4.6E-73 T 22-04-2016 L21SP4_RS01915 dbd856d0d2c07b2bd99f37f65603f385 255 SUPERFAMILY SSF46785 3 59 7.21E-13 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS01915 dbd856d0d2c07b2bd99f37f65603f385 255 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 5.2E-10 T 22-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 L21SP4_RS01915 dbd856d0d2c07b2bd99f37f65603f385 255 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 5.2E-10 T 22-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 L21SP4_RS01915 dbd856d0d2c07b2bd99f37f65603f385 255 Pfam PF00455 DeoR C terminal sensor domain 77 232 7.6E-43 T 22-04-2016 IPR014036 DeoR C-terminal sensor domain L21SP4_RS01915 dbd856d0d2c07b2bd99f37f65603f385 255 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 22-04-2016 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 L21SP4_RS01915 dbd856d0d2c07b2bd99f37f65603f385 255 SMART SM00420 6 58 1.0E-11 T 22-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 L21SP4_RS01915 dbd856d0d2c07b2bd99f37f65603f385 255 Pfam PF08220 DeoR-like helix-turn-helix domain 6 57 2.1E-13 T 22-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 L21SP4_RS01915 dbd856d0d2c07b2bd99f37f65603f385 255 PANTHER PTHR30363 1 254 4.6E-73 T 22-04-2016 L21SP4_RS04060 3fbcb384c3709138415d10ef709aab23 468 Gene3D G3DSA:3.90.1380.10 1 81 5.2E-26 T 22-04-2016 IPR029144 Threonine synthase, N-terminal L21SP4_RS04060 3fbcb384c3709138415d10ef709aab23 468 PANTHER PTHR10314 359 463 1.4E-167 T 22-04-2016 L21SP4_RS04060 3fbcb384c3709138415d10ef709aab23 468 PANTHER PTHR10314 52 327 1.4E-167 T 22-04-2016 L21SP4_RS04060 3fbcb384c3709138415d10ef709aab23 468 PANTHER PTHR10314 25 36 1.4E-167 T 22-04-2016 L21SP4_RS04060 3fbcb384c3709138415d10ef709aab23 468 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 98 112 - T 22-04-2016 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 L21SP4_RS04060 3fbcb384c3709138415d10ef709aab23 468 Pfam PF14821 Threonine synthase N terminus 2 77 2.4E-25 T 22-04-2016 IPR029144 Threonine synthase, N-terminal L21SP4_RS04060 3fbcb384c3709138415d10ef709aab23 468 TIGRFAM TIGR00260 thrC: threonine synthase 59 424 3.5E-82 T 22-04-2016 IPR004450 Threonine synthase-like L21SP4_RS04060 3fbcb384c3709138415d10ef709aab23 468 Gene3D G3DSA:3.40.50.1100 128 197 8.4E-6 T 22-04-2016 L21SP4_RS04060 3fbcb384c3709138415d10ef709aab23 468 SUPERFAMILY SSF53686 1 457 8.64E-149 T 22-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme L21SP4_RS04060 3fbcb384c3709138415d10ef709aab23 468 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 93 324 7.3E-13 T 22-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme L21SP4_RS04060 3fbcb384c3709138415d10ef709aab23 468 PANTHER PTHR10314:SF1 359 463 1.4E-167 T 22-04-2016 L21SP4_RS04060 3fbcb384c3709138415d10ef709aab23 468 PANTHER PTHR10314:SF1 52 327 1.4E-167 T 22-04-2016 L21SP4_RS04060 3fbcb384c3709138415d10ef709aab23 468 PANTHER PTHR10314:SF1 25 36 1.4E-167 T 22-04-2016 L21SP4_RS04060 3fbcb384c3709138415d10ef709aab23 468 Gene3D G3DSA:3.40.50.1100 198 426 4.5E-89 T 22-04-2016 L21SP4_RS11910 93454a9071bc03a914793ebaec0bd578 399 SUPERFAMILY SSF46689 349 398 3.23E-13 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS11910 93454a9071bc03a914793ebaec0bd578 399 SUPERFAMILY SSF46689 298 347 1.7E-5 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS11910 93454a9071bc03a914793ebaec0bd578 399 PANTHER PTHR11019:SF105 242 399 3.0E-28 T 22-04-2016 L21SP4_RS11910 93454a9071bc03a914793ebaec0bd578 399 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 365 380 2.6E-6 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 L21SP4_RS11910 93454a9071bc03a914793ebaec0bd578 399 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 380 396 2.6E-6 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 L21SP4_RS11910 93454a9071bc03a914793ebaec0bd578 399 Pfam PF10114 Sensory domain found in PocR 6 147 1.8E-10 T 22-04-2016 IPR018771 PocR domain UniPathway: UPA00148|UniPathway: UPA00621 L21SP4_RS11910 93454a9071bc03a914793ebaec0bd578 399 Pfam PF12833 Helix-turn-helix domain 319 398 1.2E-21 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP4_RS11910 93454a9071bc03a914793ebaec0bd578 399 Gene3D G3DSA:1.10.10.60 293 349 1.1E-13 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS11910 93454a9071bc03a914793ebaec0bd578 399 PANTHER PTHR11019 242 399 3.0E-28 T 22-04-2016 L21SP4_RS11910 93454a9071bc03a914793ebaec0bd578 399 Gene3D G3DSA:1.10.10.60 350 398 3.8E-17 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS11910 93454a9071bc03a914793ebaec0bd578 399 SMART SM00342 313 396 3.2E-27 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP4_RS06545 ea98c5bf26c8af52f9b53232764912fb 630 Pfam PF00884 Sulfatase 39 379 1.1E-69 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS06545 ea98c5bf26c8af52f9b53232764912fb 630 ProSitePatterns PS00149 Sulfatases signature 2. 156 166 - T 22-04-2016 IPR024607 Sulfatase, conserved site L21SP4_RS06545 ea98c5bf26c8af52f9b53232764912fb 630 Gene3D G3DSA:3.40.720.10 37 393 1.2E-109 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS06545 ea98c5bf26c8af52f9b53232764912fb 630 PANTHER PTHR10342 15 509 2.4E-144 T 22-04-2016 L21SP4_RS06545 ea98c5bf26c8af52f9b53232764912fb 630 PANTHER PTHR10342:SF199 15 509 2.4E-144 T 22-04-2016 L21SP4_RS06545 ea98c5bf26c8af52f9b53232764912fb 630 SUPERFAMILY SSF53649 38 481 3.05E-128 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS06545 ea98c5bf26c8af52f9b53232764912fb 630 Gene3D G3DSA:3.30.1120.10 394 482 8.9E-20 T 22-04-2016 L21SP4_RS11195 e45ca52b9d8fed806712928d0248a5ac 320 PANTHER PTHR10366:SF234 3 319 2.4E-104 T 22-04-2016 L21SP4_RS11195 e45ca52b9d8fed806712928d0248a5ac 320 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 247 1.6E-44 T 22-04-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 L21SP4_RS11195 e45ca52b9d8fed806712928d0248a5ac 320 PANTHER PTHR10366 3 319 2.4E-104 T 22-04-2016 L21SP4_RS11195 e45ca52b9d8fed806712928d0248a5ac 320 Gene3D G3DSA:3.40.50.720 2 310 3.2E-60 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS11195 e45ca52b9d8fed806712928d0248a5ac 320 SUPERFAMILY SSF51735 1 315 2.33E-71 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS06325 8502a39eb95e12bd454ca51550259aea 484 Gene3D G3DSA:3.50.50.60 394 469 5.9E-15 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP4_RS06325 8502a39eb95e12bd454ca51550259aea 484 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 24 127 1.7E-22 T 22-04-2016 IPR028261 Dihydroprymidine dehydrogenase domain II L21SP4_RS06325 8502a39eb95e12bd454ca51550259aea 484 PRINTS PR00419 Adrenodoxin reductase family signature 146 168 3.6E-22 T 22-04-2016 L21SP4_RS06325 8502a39eb95e12bd454ca51550259aea 484 PRINTS PR00419 Adrenodoxin reductase family signature 169 182 3.6E-22 T 22-04-2016 L21SP4_RS06325 8502a39eb95e12bd454ca51550259aea 484 PRINTS PR00419 Adrenodoxin reductase family signature 211 221 3.6E-22 T 22-04-2016 L21SP4_RS06325 8502a39eb95e12bd454ca51550259aea 484 PRINTS PR00419 Adrenodoxin reductase family signature 287 301 3.6E-22 T 22-04-2016 L21SP4_RS06325 8502a39eb95e12bd454ca51550259aea 484 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 146 463 1.3E-28 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP4_RS06325 8502a39eb95e12bd454ca51550259aea 484 PANTHER PTHR11938 1 320 8.3E-115 T 22-04-2016 L21SP4_RS06325 8502a39eb95e12bd454ca51550259aea 484 PANTHER PTHR11938 336 475 8.3E-115 T 22-04-2016 L21SP4_RS06325 8502a39eb95e12bd454ca51550259aea 484 SUPERFAMILY SSF51971 144 408 1.59E-63 T 22-04-2016 L21SP4_RS06325 8502a39eb95e12bd454ca51550259aea 484 SUPERFAMILY SSF46548 3 155 1.94E-34 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 L21SP4_RS06325 8502a39eb95e12bd454ca51550259aea 484 Gene3D G3DSA:1.10.1060.10 5 145 1.6E-38 T 22-04-2016 L21SP4_RS06325 8502a39eb95e12bd454ca51550259aea 484 PANTHER PTHR11938:SF75 1 320 8.3E-115 T 22-04-2016 L21SP4_RS06325 8502a39eb95e12bd454ca51550259aea 484 PANTHER PTHR11938:SF75 336 475 8.3E-115 T 22-04-2016 L21SP4_RS06325 8502a39eb95e12bd454ca51550259aea 484 TIGRFAM TIGR01317 GOGAT_sm_gam: glutamate synthase, NADH/NADPH, small subunit 3 478 6.3E-185 T 22-04-2016 IPR006005 Glutamate synthase, NADH/NADPH, small subunit 1 GO:0006537|GO:0016639|GO:0055114 L21SP4_RS06325 8502a39eb95e12bd454ca51550259aea 484 Gene3D G3DSA:3.50.50.60 146 243 1.1E-23 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP4_RS06325 8502a39eb95e12bd454ca51550259aea 484 Gene3D G3DSA:3.50.50.60 244 393 4.8E-42 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP4_RS06325 8502a39eb95e12bd454ca51550259aea 484 SUPERFAMILY SSF51971 382 472 1.41E-9 T 22-04-2016 L21SP4_RS07915 d710cbc814888a095463eb5098924c68 362 Pfam PF00512 His Kinase A (phospho-acceptor) domain 148 212 8.0E-15 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS07915 d710cbc814888a095463eb5098924c68 362 SMART SM00387 254 360 2.9E-31 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS07915 d710cbc814888a095463eb5098924c68 362 PRINTS PR00344 Bacterial sensor protein C-terminal signature 291 305 3.5E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS07915 d710cbc814888a095463eb5098924c68 362 PRINTS PR00344 Bacterial sensor protein C-terminal signature 309 319 3.5E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS07915 d710cbc814888a095463eb5098924c68 362 PRINTS PR00344 Bacterial sensor protein C-terminal signature 344 357 3.5E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS07915 d710cbc814888a095463eb5098924c68 362 PRINTS PR00344 Bacterial sensor protein C-terminal signature 321 339 3.5E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS07915 d710cbc814888a095463eb5098924c68 362 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 254 358 4.5E-21 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS07915 d710cbc814888a095463eb5098924c68 362 PANTHER PTHR24423 125 357 1.6E-63 T 22-04-2016 L21SP4_RS07915 d710cbc814888a095463eb5098924c68 362 SMART SM00388 148 213 5.6E-17 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS07915 d710cbc814888a095463eb5098924c68 362 Pfam PF00027 Cyclic nucleotide-binding domain 26 112 7.8E-15 T 22-04-2016 IPR000595 Cyclic nucleotide-binding domain L21SP4_RS07915 d710cbc814888a095463eb5098924c68 362 SUPERFAMILY SSF55874 202 357 4.58E-33 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS07915 d710cbc814888a095463eb5098924c68 362 Gene3D G3DSA:3.30.565.10 213 360 1.6E-37 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS07915 d710cbc814888a095463eb5098924c68 362 SUPERFAMILY SSF47384 142 211 1.53E-15 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS07915 d710cbc814888a095463eb5098924c68 362 SUPERFAMILY SSF51206 4 135 8.9E-25 T 22-04-2016 IPR018490 Cyclic nucleotide-binding-like L21SP4_RS07915 d710cbc814888a095463eb5098924c68 362 ProSitePatterns PS00889 Cyclic nucleotide-binding domain signature 2. 75 95 - T 22-04-2016 IPR018488 Cyclic nucleotide-binding, conserved site L21SP4_RS07915 d710cbc814888a095463eb5098924c68 362 SMART SM00100 7 125 2.4E-14 T 22-04-2016 IPR000595 Cyclic nucleotide-binding domain L21SP4_RS07915 d710cbc814888a095463eb5098924c68 362 Gene3D G3DSA:1.10.287.130 143 209 2.2E-13 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS07915 d710cbc814888a095463eb5098924c68 362 Gene3D G3DSA:2.60.120.10 3 134 1.9E-25 T 22-04-2016 IPR014710 RmlC-like jelly roll fold L21SP4_RS07035 f3ffb6fa717a6718d7534293f751e6b5 130 Gene3D G3DSA:3.40.50.1010 5 122 9.3E-24 T 22-04-2016 IPR029060 PIN domain-like L21SP4_RS07035 f3ffb6fa717a6718d7534293f751e6b5 130 PANTHER PTHR33653 1 123 1.1E-32 T 22-04-2016 L21SP4_RS07035 f3ffb6fa717a6718d7534293f751e6b5 130 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 5 125 11.328 T 22-04-2016 IPR022907 VapC family GO:0004540 L21SP4_RS07035 f3ffb6fa717a6718d7534293f751e6b5 130 SUPERFAMILY SSF88723 2 122 5.33E-27 T 22-04-2016 IPR029060 PIN domain-like L21SP4_RS07035 f3ffb6fa717a6718d7534293f751e6b5 130 PANTHER PTHR33653:SF2 1 123 1.1E-32 T 22-04-2016 L21SP4_RS07035 f3ffb6fa717a6718d7534293f751e6b5 130 Pfam PF01850 PIN domain 6 110 2.0E-11 T 22-04-2016 IPR002716 PIN domain L21SP4_RS12015 de1468193b55785134280b48030dd1c3 544 Gene3D G3DSA:3.90.400.10 107 168 5.8E-11 T 22-04-2016 L21SP4_RS12015 de1468193b55785134280b48030dd1c3 544 SUPERFAMILY SSF51445 7 447 1.09E-100 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily L21SP4_RS12015 de1468193b55785134280b48030dd1c3 544 PANTHER PTHR10357:SF11 426 481 3.2E-91 T 22-04-2016 L21SP4_RS12015 de1468193b55785134280b48030dd1c3 544 PANTHER PTHR10357:SF11 3 170 3.2E-91 T 22-04-2016 L21SP4_RS12015 de1468193b55785134280b48030dd1c3 544 PANTHER PTHR10357:SF11 187 391 3.2E-91 T 22-04-2016 L21SP4_RS12015 de1468193b55785134280b48030dd1c3 544 Pfam PF00128 Alpha amylase, catalytic domain 31 367 6.6E-69 T 22-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 L21SP4_RS12015 de1468193b55785134280b48030dd1c3 544 PANTHER PTHR10357 426 481 3.2E-91 T 22-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 L21SP4_RS12015 de1468193b55785134280b48030dd1c3 544 PANTHER PTHR10357 3 170 3.2E-91 T 22-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 L21SP4_RS12015 de1468193b55785134280b48030dd1c3 544 PANTHER PTHR10357 187 391 3.2E-91 T 22-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 L21SP4_RS12015 de1468193b55785134280b48030dd1c3 544 SMART SM00642 16 403 3.3E-75 T 22-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 L21SP4_RS12015 de1468193b55785134280b48030dd1c3 544 Gene3D G3DSA:3.20.20.80 188 448 2.7E-92 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP4_RS12015 de1468193b55785134280b48030dd1c3 544 Gene3D G3DSA:3.20.20.80 6 106 2.7E-92 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP4_RS04375 a11ffcdfd43ead1a81ad3ef135d675c1 733 SUPERFAMILY SSF52540 194 492 2.99E-39 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS04375 a11ffcdfd43ead1a81ad3ef135d675c1 733 Pfam PF13604 AAA domain 334 513 2.1E-42 T 22-04-2016 L21SP4_RS04375 a11ffcdfd43ead1a81ad3ef135d675c1 733 Hamap MF_01488 ATP-dependent RecD-like DNA helicase [recD2]. 14 730 27.83 T 22-04-2016 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 L21SP4_RS04375 a11ffcdfd43ead1a81ad3ef135d675c1 733 PANTHER PTHR10887 283 590 9.8E-102 T 22-04-2016 L21SP4_RS04375 a11ffcdfd43ead1a81ad3ef135d675c1 733 PANTHER PTHR10887 654 732 9.8E-102 T 22-04-2016 L21SP4_RS04375 a11ffcdfd43ead1a81ad3ef135d675c1 733 Pfam PF13538 UvrD-like helicase C-terminal domain 654 701 6.3E-19 T 22-04-2016 IPR027785 UvrD-like helicase C-terminal domain L21SP4_RS04375 a11ffcdfd43ead1a81ad3ef135d675c1 733 Gene3D G3DSA:3.40.50.300 652 705 1.5E-17 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS04375 a11ffcdfd43ead1a81ad3ef135d675c1 733 Gene3D G3DSA:1.10.150.20 102 171 4.9E-4 T 22-04-2016 L21SP4_RS04375 a11ffcdfd43ead1a81ad3ef135d675c1 733 PANTHER PTHR10887:SF284 283 590 9.8E-102 T 22-04-2016 L21SP4_RS04375 a11ffcdfd43ead1a81ad3ef135d675c1 733 PANTHER PTHR10887:SF284 654 732 9.8E-102 T 22-04-2016 L21SP4_RS04375 a11ffcdfd43ead1a81ad3ef135d675c1 733 SUPERFAMILY SSF47781 94 170 7.66E-9 T 22-04-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 L21SP4_RS04375 a11ffcdfd43ead1a81ad3ef135d675c1 733 SMART SM00382 348 463 1.7E-7 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS04375 a11ffcdfd43ead1a81ad3ef135d675c1 733 Gene3D G3DSA:3.40.50.300 601 633 1.9E-4 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS04375 a11ffcdfd43ead1a81ad3ef135d675c1 733 Gene3D G3DSA:3.40.50.300 294 515 5.9E-45 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS04375 a11ffcdfd43ead1a81ad3ef135d675c1 733 Pfam PF14520 Helix-hairpin-helix domain 103 152 2.8E-5 T 22-04-2016 L21SP4_RS04375 a11ffcdfd43ead1a81ad3ef135d675c1 733 Pfam PF14490 Helix-hairpin-helix containing domain 154 242 4.4E-28 T 22-04-2016 IPR029493 RecD helicase-like helix-hairpin-helix domain L21SP4_RS04375 a11ffcdfd43ead1a81ad3ef135d675c1 733 SUPERFAMILY SSF52540 555 726 1.29E-60 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS04375 a11ffcdfd43ead1a81ad3ef135d675c1 733 TIGRFAM TIGR01448 recD_rel: helicase, RecD/TraA family 17 727 2.7E-214 T 22-04-2016 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 L21SP4_RS04375 a11ffcdfd43ead1a81ad3ef135d675c1 733 SUPERFAMILY SSF52540 446 511 1.29E-60 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS06710 413c0bc72c77ade10c60097892c700a4 494 ProSitePatterns PS00149 Sulfatases signature 2. 122 132 - T 22-04-2016 IPR024607 Sulfatase, conserved site L21SP4_RS06710 413c0bc72c77ade10c60097892c700a4 494 Gene3D G3DSA:3.30.1120.10 380 467 2.0E-12 T 22-04-2016 L21SP4_RS06710 413c0bc72c77ade10c60097892c700a4 494 Pfam PF00884 Sulfatase 30 357 1.9E-78 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS06710 413c0bc72c77ade10c60097892c700a4 494 SUPERFAMILY SSF53649 29 462 8.43E-119 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS06710 413c0bc72c77ade10c60097892c700a4 494 Gene3D G3DSA:3.40.720.10 27 378 7.9E-109 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS06710 413c0bc72c77ade10c60097892c700a4 494 PANTHER PTHR10342 1 486 1.8E-150 T 22-04-2016 L21SP4_RS06710 413c0bc72c77ade10c60097892c700a4 494 PANTHER PTHR10342:SF199 1 486 1.8E-150 T 22-04-2016 L21SP4_RS07060 7533c1f8548ee9d1eb911ea3711aa728 426 SUPERFAMILY SSF55347 132 297 1.96E-49 T 22-04-2016 L21SP4_RS07060 7533c1f8548ee9d1eb911ea3711aa728 426 SUPERFAMILY SSF51735 1 153 4.3E-29 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS07060 7533c1f8548ee9d1eb911ea3711aa728 426 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 5 124 7.8E-19 T 22-04-2016 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 L21SP4_RS07060 7533c1f8548ee9d1eb911ea3711aa728 426 PANTHER PTHR21499 1 364 4.8E-124 T 22-04-2016 L21SP4_RS07060 7533c1f8548ee9d1eb911ea3711aa728 426 PIRSF PIRSF000098 1 424 2.2E-149 T 22-04-2016 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3|UniPathway: UPA00050|UniPathway: UPA00051 L21SP4_RS07060 7533c1f8548ee9d1eb911ea3711aa728 426 Gene3D G3DSA:3.30.360.10 144 294 2.0E-52 T 22-04-2016 L21SP4_RS07060 7533c1f8548ee9d1eb911ea3711aa728 426 SUPERFAMILY SSF55021 343 412 1.32E-13 T 22-04-2016 L21SP4_RS07060 7533c1f8548ee9d1eb911ea3711aa728 426 Pfam PF01842 ACT domain 347 410 7.0E-14 T 22-04-2016 IPR002912 ACT domain GO:0008152|GO:0016597 L21SP4_RS07060 7533c1f8548ee9d1eb911ea3711aa728 426 Gene3D G3DSA:3.40.50.720 1 143 8.7E-44 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS07060 7533c1f8548ee9d1eb911ea3711aa728 426 PANTHER PTHR21499:SF2 1 364 4.8E-124 T 22-04-2016 L21SP4_RS07060 7533c1f8548ee9d1eb911ea3711aa728 426 Pfam PF00742 Homoserine dehydrogenase 132 310 1.2E-59 T 22-04-2016 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3|UniPathway: UPA00050|UniPathway: UPA00051 L21SP4_RS07060 7533c1f8548ee9d1eb911ea3711aa728 426 Gene3D G3DSA:3.30.70.260 341 411 8.1E-9 T 22-04-2016 L21SP4_RS09310 4e3e22852406a7eea97e727cbc854160 426 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 425 33.879 T 22-04-2016 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 L21SP4_RS09310 4e3e22852406a7eea97e727cbc854160 426 PANTHER PTHR21090 1 424 4.2E-117 T 22-04-2016 L21SP4_RS09310 4e3e22852406a7eea97e727cbc854160 426 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 410 3.7E-61 T 22-04-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 L21SP4_RS09310 4e3e22852406a7eea97e727cbc854160 426 Gene3D G3DSA:3.65.10.10 219 425 3.6E-40 T 22-04-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 L21SP4_RS09310 4e3e22852406a7eea97e727cbc854160 426 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 424 4.9E-134 T 22-04-2016 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 L21SP4_RS09310 4e3e22852406a7eea97e727cbc854160 426 SUPERFAMILY SSF55205 1 425 9.32E-100 T 22-04-2016 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 L21SP4_RS09310 4e3e22852406a7eea97e727cbc854160 426 Gene3D G3DSA:3.65.10.10 22 218 8.6E-56 T 22-04-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 L21SP4_RS08620 9628f383965f59f5404a0ce11bc9d83a 426 SUPERFAMILY SSF53244 282 418 3.39E-37 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 L21SP4_RS08620 9628f383965f59f5404a0ce11bc9d83a 426 Pfam PF08245 Mur ligase middle domain 91 236 4.4E-20 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 L21SP4_RS08620 9628f383965f59f5404a0ce11bc9d83a 426 Gene3D G3DSA:3.90.190.20 282 416 1.4E-39 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 L21SP4_RS08620 9628f383965f59f5404a0ce11bc9d83a 426 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 6 419 27.551 T 22-04-2016 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 L21SP4_RS08620 9628f383965f59f5404a0ce11bc9d83a 426 SUPERFAMILY SSF51984 5 75 1.07E-9 T 22-04-2016 L21SP4_RS08620 9628f383965f59f5404a0ce11bc9d83a 426 Gene3D G3DSA:3.40.1190.10 75 280 9.7E-41 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 L21SP4_RS08620 9628f383965f59f5404a0ce11bc9d83a 426 SUPERFAMILY SSF53623 78 279 2.88E-36 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 L21SP4_RS08620 9628f383965f59f5404a0ce11bc9d83a 426 PANTHER PTHR23135:SF2 1 421 8.6E-107 T 22-04-2016 L21SP4_RS08620 9628f383965f59f5404a0ce11bc9d83a 426 Gene3D G3DSA:3.40.50.720 6 43 2.5E-5 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS08620 9628f383965f59f5404a0ce11bc9d83a 426 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 8 417 1.6E-98 T 22-04-2016 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 L21SP4_RS08620 9628f383965f59f5404a0ce11bc9d83a 426 PANTHER PTHR23135 1 421 8.6E-107 T 22-04-2016 L21SP4_RS03885 6e86f39d08daf09eefa3b7f21f4ca2c7 386 Pfam PF01702 Queuine tRNA-ribosyltransferase 143 375 4.9E-82 T 22-04-2016 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|UniPathway: UPA00392 L21SP4_RS03885 6e86f39d08daf09eefa3b7f21f4ca2c7 386 PANTHER PTHR21148:SF26 10 380 7.9E-152 T 22-04-2016 L21SP4_RS03885 6e86f39d08daf09eefa3b7f21f4ca2c7 386 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 15 373 51.95 T 22-04-2016 IPR004803 Queuine tRNA-ribosyltransferase GO:0008033|GO:0008479|GO:0008616 MetaCyc: PWY-6700|UniPathway: UPA00392 L21SP4_RS03885 6e86f39d08daf09eefa3b7f21f4ca2c7 386 PANTHER PTHR21148 10 380 7.9E-152 T 22-04-2016 L21SP4_RS03885 6e86f39d08daf09eefa3b7f21f4ca2c7 386 SUPERFAMILY SSF51713 16 378 7.32E-143 T 22-04-2016 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|UniPathway: UPA00392 L21SP4_RS03885 6e86f39d08daf09eefa3b7f21f4ca2c7 386 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 18 379 1.1E-143 T 22-04-2016 IPR004803 Queuine tRNA-ribosyltransferase GO:0008033|GO:0008479|GO:0008616 MetaCyc: PWY-6700|UniPathway: UPA00392 L21SP4_RS03885 6e86f39d08daf09eefa3b7f21f4ca2c7 386 Gene3D G3DSA:3.20.20.105 12 379 1.3E-152 T 22-04-2016 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|UniPathway: UPA00392 L21SP4_RS03885 6e86f39d08daf09eefa3b7f21f4ca2c7 386 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 17 379 1.1E-140 T 22-04-2016 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|UniPathway: UPA00392 L21SP4_RS12180 cb998dd0069199ce4b4308bdc91d4372 367 PANTHER PTHR10804 8 357 1.6E-59 T 22-04-2016 L21SP4_RS12180 cb998dd0069199ce4b4308bdc91d4372 367 SUPERFAMILY SSF55920 120 364 5.1E-47 T 22-04-2016 IPR000994 Peptidase M24, structural domain L21SP4_RS12180 cb998dd0069199ce4b4308bdc91d4372 367 Gene3D G3DSA:3.90.230.10 121 364 8.9E-51 T 22-04-2016 IPR000994 Peptidase M24, structural domain L21SP4_RS12180 cb998dd0069199ce4b4308bdc91d4372 367 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 298 310 - T 22-04-2016 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site L21SP4_RS12180 cb998dd0069199ce4b4308bdc91d4372 367 Pfam PF00557 Metallopeptidase family M24 130 350 2.0E-43 T 22-04-2016 IPR000994 Peptidase M24, structural domain L21SP4_RS12180 cb998dd0069199ce4b4308bdc91d4372 367 PANTHER PTHR10804:SF110 8 357 1.6E-59 T 22-04-2016 L21SP4_RS10525 532bb94ab614cbe5d128063d5e7f83d2 393 SUPERFAMILY SSF54919 181 370 1.37E-30 T 22-04-2016 L21SP4_RS10525 532bb94ab614cbe5d128063d5e7f83d2 393 PANTHER PTHR11349:SF63 171 239 1.0E-13 T 22-04-2016 L21SP4_RS10525 532bb94ab614cbe5d128063d5e7f83d2 393 Pfam PF00334 Nucleoside diphosphate kinase 6 128 1.2E-6 T 22-04-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 L21SP4_RS10525 532bb94ab614cbe5d128063d5e7f83d2 393 Pfam PF00334 Nucleoside diphosphate kinase 182 233 1.1E-5 T 22-04-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 L21SP4_RS10525 532bb94ab614cbe5d128063d5e7f83d2 393 Pfam PF00334 Nucleoside diphosphate kinase 311 371 2.5E-16 T 22-04-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 L21SP4_RS10525 532bb94ab614cbe5d128063d5e7f83d2 393 Gene3D G3DSA:3.30.70.141 279 376 7.7E-34 T 22-04-2016 L21SP4_RS10525 532bb94ab614cbe5d128063d5e7f83d2 393 Gene3D G3DSA:3.30.70.141 181 235 7.7E-34 T 22-04-2016 L21SP4_RS10525 532bb94ab614cbe5d128063d5e7f83d2 393 PANTHER PTHR11349 171 239 1.0E-13 T 22-04-2016 L21SP4_RS10525 532bb94ab614cbe5d128063d5e7f83d2 393 PANTHER PTHR11349 299 371 1.0E-13 T 22-04-2016 L21SP4_RS10525 532bb94ab614cbe5d128063d5e7f83d2 393 Gene3D G3DSA:3.30.70.141 4 161 1.1E-11 T 22-04-2016 L21SP4_RS10525 532bb94ab614cbe5d128063d5e7f83d2 393 PANTHER PTHR11349 40 47 1.0E-13 T 22-04-2016 L21SP4_RS10525 532bb94ab614cbe5d128063d5e7f83d2 393 SUPERFAMILY SSF54919 4 160 5.63E-13 T 22-04-2016 L21SP4_RS10525 532bb94ab614cbe5d128063d5e7f83d2 393 SMART SM00562 181 379 9.6E-12 T 22-04-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 L21SP4_RS10525 532bb94ab614cbe5d128063d5e7f83d2 393 PANTHER PTHR11349:SF63 40 47 1.0E-13 T 22-04-2016 L21SP4_RS10525 532bb94ab614cbe5d128063d5e7f83d2 393 PANTHER PTHR11349:SF63 299 371 1.0E-13 T 22-04-2016 L21SP4_RS10525 532bb94ab614cbe5d128063d5e7f83d2 393 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 353 361 - T 22-04-2016 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 L21SP4_RS11085 224d324174ebb6d91cdda6bd9c8b628b 393 SUPERFAMILY SSF55874 228 385 7.86E-17 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS11085 224d324174ebb6d91cdda6bd9c8b628b 393 Pfam PF08448 PAS fold 39 168 5.6E-6 T 22-04-2016 IPR013656 PAS fold-4 L21SP4_RS11085 224d324174ebb6d91cdda6bd9c8b628b 393 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 281 385 1.0E-8 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS11085 224d324174ebb6d91cdda6bd9c8b628b 393 PANTHER PTHR24423 12 388 1.1E-23 T 22-04-2016 L21SP4_RS11085 224d324174ebb6d91cdda6bd9c8b628b 393 SUPERFAMILY SSF55785 15 164 2.26E-5 T 22-04-2016 IPR000014 PAS domain L21SP4_RS11085 224d324174ebb6d91cdda6bd9c8b628b 393 SMART SM00387 280 387 1.1E-5 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS11085 224d324174ebb6d91cdda6bd9c8b628b 393 Gene3D G3DSA:3.30.450.20 38 164 7.2E-8 T 22-04-2016 L21SP4_RS11085 224d324174ebb6d91cdda6bd9c8b628b 393 Gene3D G3DSA:3.30.565.10 238 384 1.0E-17 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS10945 7aa0adbcd025e276ce705dcc04fb16c7 477 Pfam PF13181 Tetratricopeptide repeat 394 424 0.078 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS10945 7aa0adbcd025e276ce705dcc04fb16c7 477 SUPERFAMILY SSF48452 118 236 7.59E-22 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS10945 7aa0adbcd025e276ce705dcc04fb16c7 477 Pfam PF13432 Tetratricopeptide repeat 201 247 2.6E-5 T 22-04-2016 L21SP4_RS10945 7aa0adbcd025e276ce705dcc04fb16c7 477 Pfam PF13432 Tetratricopeptide repeat 120 180 8.6E-4 T 22-04-2016 L21SP4_RS10945 7aa0adbcd025e276ce705dcc04fb16c7 477 Pfam PF13432 Tetratricopeptide repeat 254 318 2.8E-5 T 22-04-2016 L21SP4_RS10945 7aa0adbcd025e276ce705dcc04fb16c7 477 Gene3D G3DSA:1.25.40.10 113 319 1.6E-33 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS10945 7aa0adbcd025e276ce705dcc04fb16c7 477 Gene3D G3DSA:1.25.40.10 324 459 3.3E-14 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS10945 7aa0adbcd025e276ce705dcc04fb16c7 477 SUPERFAMILY SSF81901 355 460 7.32E-19 T 22-04-2016 L21SP4_RS10945 7aa0adbcd025e276ce705dcc04fb16c7 477 SUPERFAMILY SSF81901 226 315 7.32E-19 T 22-04-2016 L21SP4_RS10945 7aa0adbcd025e276ce705dcc04fb16c7 477 SMART SM00028 148 181 0.051 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS10945 7aa0adbcd025e276ce705dcc04fb16c7 477 SMART SM00028 427 460 11.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS10945 7aa0adbcd025e276ce705dcc04fb16c7 477 SMART SM00028 182 215 9.2 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS10945 7aa0adbcd025e276ce705dcc04fb16c7 477 SMART SM00028 393 426 14.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS10945 7aa0adbcd025e276ce705dcc04fb16c7 477 SMART SM00028 284 317 0.87 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS10945 7aa0adbcd025e276ce705dcc04fb16c7 477 SMART SM00028 114 147 19.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS10945 7aa0adbcd025e276ce705dcc04fb16c7 477 PANTHER PTHR23083 361 459 1.1E-35 T 22-04-2016 L21SP4_RS10945 7aa0adbcd025e276ce705dcc04fb16c7 477 PANTHER PTHR23083 85 319 1.1E-35 T 22-04-2016 L21SP4_RS08320 71f487883c5ee8967cd041cccc99c162 162 Pfam PF00333 Ribosomal protein S5, N-terminal domain 14 77 2.9E-27 T 22-04-2016 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 L21SP4_RS08320 71f487883c5ee8967cd041cccc99c162 162 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 161 32.559 T 22-04-2016 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 L21SP4_RS08320 71f487883c5ee8967cd041cccc99c162 162 ProSitePatterns PS00585 Ribosomal protein S5 signature. 31 63 - T 22-04-2016 IPR018192 Ribosomal protein S5, N-terminal, conserved site L21SP4_RS08320 71f487883c5ee8967cd041cccc99c162 162 SUPERFAMILY SSF54211 82 160 6.83E-24 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold L21SP4_RS08320 71f487883c5ee8967cd041cccc99c162 162 Gene3D G3DSA:3.30.230.10 79 160 3.4E-28 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup L21SP4_RS08320 71f487883c5ee8967cd041cccc99c162 162 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 11 161 3.0E-62 T 22-04-2016 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 L21SP4_RS08320 71f487883c5ee8967cd041cccc99c162 162 Pfam PF03719 Ribosomal protein S5, C-terminal domain 90 159 9.4E-27 T 22-04-2016 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 L21SP4_RS08320 71f487883c5ee8967cd041cccc99c162 162 Gene3D G3DSA:3.30.160.20 12 74 2.2E-28 T 22-04-2016 IPR014720 Double-stranded RNA-binding domain L21SP4_RS08320 71f487883c5ee8967cd041cccc99c162 162 SUPERFAMILY SSF54768 11 78 5.13E-21 T 22-04-2016 L21SP4_RS08320 71f487883c5ee8967cd041cccc99c162 162 PANTHER PTHR13718 13 155 5.4E-60 T 22-04-2016 IPR000851 Ribosomal protein S5 GO:0003735|GO:0005840|GO:0006412 L21SP4_RS03900 7d9fe776393571c713a9d279fe1f8ea0 572 PANTHER PTHR30255 1 560 1.2E-201 T 22-04-2016 L21SP4_RS03900 7d9fe776393571c713a9d279fe1f8ea0 572 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 20 557 4.9E-153 T 22-04-2016 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 L21SP4_RS03900 7d9fe776393571c713a9d279fe1f8ea0 572 PANTHER PTHR30255:SF2 1 560 1.2E-201 T 22-04-2016 L21SP4_RS03900 7d9fe776393571c713a9d279fe1f8ea0 572 SUPERFAMILY SSF64182 48 453 3.53E-113 T 22-04-2016 L21SP4_RS03900 7d9fe776393571c713a9d279fe1f8ea0 572 Gene3D G3DSA:3.40.50.2300 118 180 1.3E-4 T 22-04-2016 L21SP4_RS03900 7d9fe776393571c713a9d279fe1f8ea0 572 Pfam PF02272 DHHA1 domain 374 437 2.7E-11 T 22-04-2016 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7 L21SP4_RS03900 7d9fe776393571c713a9d279fe1f8ea0 572 Pfam PF01368 DHH family 74 205 3.7E-11 T 22-04-2016 IPR001667 DDH domain L21SP4_RS09935 9c360443e5b72c5f2b6540e010f6e114 387 PRINTS PR00474 Glutamate 5-kinase family signature 86 114 6.4E-48 T 22-04-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 L21SP4_RS09935 9c360443e5b72c5f2b6540e010f6e114 387 PRINTS PR00474 Glutamate 5-kinase family signature 158 185 6.4E-48 T 22-04-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 L21SP4_RS09935 9c360443e5b72c5f2b6540e010f6e114 387 PRINTS PR00474 Glutamate 5-kinase family signature 52 66 6.4E-48 T 22-04-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 L21SP4_RS09935 9c360443e5b72c5f2b6540e010f6e114 387 PRINTS PR00474 Glutamate 5-kinase family signature 126 147 6.4E-48 T 22-04-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 L21SP4_RS09935 9c360443e5b72c5f2b6540e010f6e114 387 PRINTS PR00474 Glutamate 5-kinase family signature 217 237 6.4E-48 T 22-04-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 L21SP4_RS09935 9c360443e5b72c5f2b6540e010f6e114 387 Gene3D G3DSA:2.30.130.10 283 374 2.7E-24 T 22-04-2016 IPR015947 PUA-like domain L21SP4_RS09935 9c360443e5b72c5f2b6540e010f6e114 387 Pfam PF01472 PUA domain 285 357 4.5E-20 T 22-04-2016 IPR002478 PUA domain GO:0003723 L21SP4_RS09935 9c360443e5b72c5f2b6540e010f6e114 387 Pfam PF00696 Amino acid kinase family 16 243 6.6E-37 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 L21SP4_RS09935 9c360443e5b72c5f2b6540e010f6e114 387 PANTHER PTHR11063:SF6 15 378 4.6E-105 T 22-04-2016 L21SP4_RS09935 9c360443e5b72c5f2b6540e010f6e114 387 PANTHER PTHR11063 15 378 4.6E-105 T 22-04-2016 L21SP4_RS09935 9c360443e5b72c5f2b6540e010f6e114 387 SUPERFAMILY SSF88697 285 375 3.09E-22 T 22-04-2016 IPR015947 PUA-like domain L21SP4_RS09935 9c360443e5b72c5f2b6540e010f6e114 387 Gene3D G3DSA:3.40.1160.10 12 267 1.3E-50 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 L21SP4_RS09935 9c360443e5b72c5f2b6540e010f6e114 387 Hamap MF_00456 Glutamate 5-kinase [proB]. 15 266 34.163 T 22-04-2016 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|UniPathway: UPA00098 L21SP4_RS09935 9c360443e5b72c5f2b6540e010f6e114 387 SMART SM00359 285 368 1.9E-15 T 22-04-2016 IPR002478 PUA domain GO:0003723 L21SP4_RS09935 9c360443e5b72c5f2b6540e010f6e114 387 PIRSF PIRSF000729 11 377 1.2E-126 T 22-04-2016 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|UniPathway: UPA00098 L21SP4_RS09935 9c360443e5b72c5f2b6540e010f6e114 387 SUPERFAMILY SSF53633 15 265 2.23E-59 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 L21SP4_RS09935 9c360443e5b72c5f2b6540e010f6e114 387 TIGRFAM TIGR01027 proB: glutamate 5-kinase 15 375 2.0E-124 T 22-04-2016 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|UniPathway: UPA00098 L21SP4_RS09935 9c360443e5b72c5f2b6540e010f6e114 387 ProSitePatterns PS00902 Glutamate 5-kinase signature. 215 232 - T 22-04-2016 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|UniPathway: UPA00098 L21SP4_RS08600 f0acd3f17b5a8b08829ac8864a87e601 507 PANTHER PTHR11772 2 451 4.3E-158 T 22-04-2016 L21SP4_RS08600 f0acd3f17b5a8b08829ac8864a87e601 507 SUPERFAMILY SSF56235 1 180 2.83E-52 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal L21SP4_RS08600 f0acd3f17b5a8b08829ac8864a87e601 507 Pfam PF13537 Glutamine amidotransferase domain 43 157 1.1E-36 T 22-04-2016 IPR017932 Glutamine amidotransferase type 2 domain L21SP4_RS08600 f0acd3f17b5a8b08829ac8864a87e601 507 PANTHER PTHR11772:SF2 2 451 4.3E-158 T 22-04-2016 L21SP4_RS08600 f0acd3f17b5a8b08829ac8864a87e601 507 SUPERFAMILY SSF52402 193 451 1.83E-76 T 22-04-2016 L21SP4_RS08600 f0acd3f17b5a8b08829ac8864a87e601 507 Pfam PF00733 Asparagine synthase 342 456 2.3E-27 T 22-04-2016 IPR001962 Asparagine synthase GO:0004066|GO:0006529 L21SP4_RS08600 f0acd3f17b5a8b08829ac8864a87e601 507 Pfam PF00733 Asparagine synthase 202 338 3.1E-49 T 22-04-2016 IPR001962 Asparagine synthase GO:0004066|GO:0006529 L21SP4_RS08600 f0acd3f17b5a8b08829ac8864a87e601 507 Gene3D G3DSA:3.40.50.620 192 462 1.5E-91 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP4_RS08600 f0acd3f17b5a8b08829ac8864a87e601 507 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 347 4.8E-102 T 22-04-2016 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|UniPathway: UPA00134 L21SP4_RS08600 f0acd3f17b5a8b08829ac8864a87e601 507 Gene3D G3DSA:3.60.20.10 1 178 1.5E-56 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal L21SP4_RS08450 54147749080f5f7d8872a86138c0ee70 231 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 39.018 T 22-04-2016 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 L21SP4_RS08450 54147749080f5f7d8872a86138c0ee70 231 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 4 227 7.7E-91 T 22-04-2016 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 L21SP4_RS08450 54147749080f5f7d8872a86138c0ee70 231 Gene3D G3DSA:3.30.190.20 161 226 5.2E-38 T 22-04-2016 IPR016094 Ribosomal protein L1, 2-layer alpha/beta-sandwich GO:0003723 L21SP4_RS08450 54147749080f5f7d8872a86138c0ee70 231 Gene3D G3DSA:3.30.190.20 21 68 5.2E-38 T 22-04-2016 IPR016094 Ribosomal protein L1, 2-layer alpha/beta-sandwich GO:0003723 L21SP4_RS08450 54147749080f5f7d8872a86138c0ee70 231 Gene3D G3DSA:3.40.50.790 69 159 8.6E-39 T 22-04-2016 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich L21SP4_RS08450 54147749080f5f7d8872a86138c0ee70 231 PIRSF PIRSF002155 1 227 1.3E-68 T 22-04-2016 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 L21SP4_RS08450 54147749080f5f7d8872a86138c0ee70 231 PANTHER PTHR23105:SF5 23 224 1.5E-69 T 22-04-2016 L21SP4_RS08450 54147749080f5f7d8872a86138c0ee70 231 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 22-04-2016 IPR023673 Ribosomal protein L1, conserved site L21SP4_RS08450 54147749080f5f7d8872a86138c0ee70 231 PANTHER PTHR23105 23 224 1.5E-69 T 22-04-2016 L21SP4_RS08450 54147749080f5f7d8872a86138c0ee70 231 Pfam PF00687 Ribosomal protein L1p/L10e family 33 220 2.0E-49 T 22-04-2016 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein L21SP4_RS08450 54147749080f5f7d8872a86138c0ee70 231 SUPERFAMILY SSF56808 6 224 2.49E-72 T 22-04-2016 IPR023674 Ribosomal protein L1-like L21SP4_RS01580 f77f5c131e13f9014db673d3f4a169a8 226 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 7 29 3.8E-9 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site L21SP4_RS01580 f77f5c131e13f9014db673d3f4a169a8 226 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 8 28 - T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site L21SP4_RS01580 f77f5c131e13f9014db673d3f4a169a8 226 SUPERFAMILY SSF54523 10 102 7.85E-14 T 22-04-2016 L21SP4_RS01580 f77f5c131e13f9014db673d3f4a169a8 226 Pfam PF13633 Prokaryotic N-terminal methylation site 8 32 6.0E-10 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site L21SP4_RS01580 f77f5c131e13f9014db673d3f4a169a8 226 Gene3D G3DSA:3.30.700.10 10 64 1.3E-5 T 22-04-2016 L21SP4_RS11295 1a5a4afb3280579cd16b52d6a28412dc 489 Pfam PF13440 Polysaccharide biosynthesis protein 31 323 1.0E-85 T 22-04-2016 L21SP4_RS11295 1a5a4afb3280579cd16b52d6a28412dc 489 PANTHER PTHR30250 1 456 2.3E-76 T 22-04-2016 L21SP4_RS11295 1a5a4afb3280579cd16b52d6a28412dc 489 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 325 463 1.8E-11 T 22-04-2016 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain L21SP4_RS11295 1a5a4afb3280579cd16b52d6a28412dc 489 PANTHER PTHR30250:SF0 1 456 2.3E-76 T 22-04-2016 L21SP4_RS04445 e2a8d8954152b0015bbd1f5f444dae0f 381 SUPERFAMILY SSF51126 150 372 5.89E-28 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor L21SP4_RS04445 e2a8d8954152b0015bbd1f5f444dae0f 381 SUPERFAMILY SSF51126 21 116 5.89E-28 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor L21SP4_RS04445 e2a8d8954152b0015bbd1f5f444dae0f 381 Pfam PF12708 Pectate lyase superfamily protein 40 109 9.8E-7 T 22-04-2016 IPR024535 Pectate lyase superfamily protein L21SP4_RS04445 e2a8d8954152b0015bbd1f5f444dae0f 381 Gene3D G3DSA:2.160.20.10 22 377 3.0E-22 T 22-04-2016 IPR012334 Pectin lyase fold L21SP4_RS08080 722e2f9df2753fe90cf773a7a7c40faa 701 Gene3D G3DSA:3.30.230.70 3 225 1.5E-72 T 22-04-2016 IPR027408 PNPase/RNase PH domain L21SP4_RS08080 722e2f9df2753fe90cf773a7a7c40faa 701 Gene3D G3DSA:3.30.230.70 316 543 1.5E-76 T 22-04-2016 IPR027408 PNPase/RNase PH domain L21SP4_RS08080 722e2f9df2753fe90cf773a7a7c40faa 701 PANTHER PTHR11252 7 701 0.0 T 22-04-2016 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 L21SP4_RS08080 722e2f9df2753fe90cf773a7a7c40faa 701 Pfam PF00013 KH domain 557 613 1.7E-9 T 22-04-2016 IPR004088 K Homology domain, type 1 GO:0003723 L21SP4_RS08080 722e2f9df2753fe90cf773a7a7c40faa 701 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 12 691 6.2E-272 T 22-04-2016 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 L21SP4_RS08080 722e2f9df2753fe90cf773a7a7c40faa 701 SUPERFAMILY SSF54211 307 492 2.68E-41 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold L21SP4_RS08080 722e2f9df2753fe90cf773a7a7c40faa 701 SUPERFAMILY SSF55666 452 559 8.55E-25 T 22-04-2016 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: REACT_21257 L21SP4_RS08080 722e2f9df2753fe90cf773a7a7c40faa 701 Pfam PF03725 3' exoribonuclease family, domain 2 147 209 3.4E-12 T 22-04-2016 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: REACT_21257 L21SP4_RS08080 722e2f9df2753fe90cf773a7a7c40faa 701 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 3 693 27.841 T 22-04-2016 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 L21SP4_RS08080 722e2f9df2753fe90cf773a7a7c40faa 701 Gene3D G3DSA:3.30.1370.10 551 618 2.0E-23 T 22-04-2016 IPR004088 K Homology domain, type 1 GO:0003723 L21SP4_RS08080 722e2f9df2753fe90cf773a7a7c40faa 701 SUPERFAMILY SSF54791 548 621 4.27E-14 T 22-04-2016 IPR004088 K Homology domain, type 1 GO:0003723 L21SP4_RS08080 722e2f9df2753fe90cf773a7a7c40faa 701 Gene3D G3DSA:2.40.50.140 619 694 2.1E-23 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold L21SP4_RS08080 722e2f9df2753fe90cf773a7a7c40faa 701 Gene3D G3DSA:1.10.10.400 227 315 2.5E-15 T 22-04-2016 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 L21SP4_RS08080 722e2f9df2753fe90cf773a7a7c40faa 701 SUPERFAMILY SSF46915 227 325 1.19E-14 T 22-04-2016 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 L21SP4_RS08080 722e2f9df2753fe90cf773a7a7c40faa 701 Pfam PF01138 3' exoribonuclease family, domain 1 18 144 5.0E-16 T 22-04-2016 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: REACT_21257 L21SP4_RS08080 722e2f9df2753fe90cf773a7a7c40faa 701 Pfam PF01138 3' exoribonuclease family, domain 1 324 455 2.0E-17 T 22-04-2016 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: REACT_21257 L21SP4_RS08080 722e2f9df2753fe90cf773a7a7c40faa 701 SUPERFAMILY SSF54211 3 144 3.24E-40 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold L21SP4_RS08080 722e2f9df2753fe90cf773a7a7c40faa 701 SMART SM00316 620 690 1.9E-21 T 22-04-2016 IPR022967 RNA-binding domain, S1 L21SP4_RS08080 722e2f9df2753fe90cf773a7a7c40faa 701 PIRSF PIRSF005499 1 701 4.1E-266 T 22-04-2016 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 L21SP4_RS08080 722e2f9df2753fe90cf773a7a7c40faa 701 SMART SM00322 552 617 2.5E-10 T 22-04-2016 IPR004087 K Homology domain GO:0003676 L21SP4_RS08080 722e2f9df2753fe90cf773a7a7c40faa 701 SUPERFAMILY SSF50249 609 694 7.71E-19 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold L21SP4_RS08080 722e2f9df2753fe90cf773a7a7c40faa 701 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 247 316 1.0E-9 T 22-04-2016 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 L21SP4_RS08080 722e2f9df2753fe90cf773a7a7c40faa 701 SUPERFAMILY SSF55666 138 228 1.54E-22 T 22-04-2016 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: REACT_21257 L21SP4_RS08080 722e2f9df2753fe90cf773a7a7c40faa 701 Pfam PF00575 S1 RNA binding domain 619 690 6.0E-15 T 22-04-2016 IPR003029 S1 domain GO:0003676 L21SP4_RS12095 1f139365512578d562b133cc7cc9bbef 428 SUPERFAMILY SSF54631 194 326 2.78E-25 T 22-04-2016 L21SP4_RS12095 1f139365512578d562b133cc7cc9bbef 428 Pfam PF00571 CBS domain 272 323 1.3E-5 T 22-04-2016 IPR000644 CBS domain L21SP4_RS12095 1f139365512578d562b133cc7cc9bbef 428 Pfam PF03471 Transporter associated domain 337 416 8.8E-16 T 22-04-2016 IPR005170 Transporter-associated domain L21SP4_RS12095 1f139365512578d562b133cc7cc9bbef 428 Gene3D G3DSA:3.30.465.10 315 416 3.5E-22 T 22-04-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 L21SP4_RS12095 1f139365512578d562b133cc7cc9bbef 428 SMART SM01091 335 418 1.6E-16 T 22-04-2016 IPR005170 Transporter-associated domain L21SP4_RS12095 1f139365512578d562b133cc7cc9bbef 428 SUPERFAMILY SSF56176 337 421 2.14E-15 T 22-04-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 L21SP4_RS12095 1f139365512578d562b133cc7cc9bbef 428 Gene3D G3DSA:3.10.580.10 192 314 7.7E-16 T 22-04-2016 L21SP4_RS12095 1f139365512578d562b133cc7cc9bbef 428 PANTHER PTHR22777 11 422 1.1E-87 T 22-04-2016 L21SP4_RS12095 1f139365512578d562b133cc7cc9bbef 428 Pfam PF01595 Domain of unknown function DUF21 14 184 2.6E-33 T 22-04-2016 IPR002550 Domain of unknown function DUF21 L21SP4_RS08680 9b6224e7f0a6349ca22d1319304d67b0 679 SMART SM00889 460 578 2.9E-55 T 22-04-2016 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 L21SP4_RS08680 9b6224e7f0a6349ca22d1319304d67b0 679 PANTHER PTHR23115 241 671 2.2E-219 T 22-04-2016 L21SP4_RS08680 9b6224e7f0a6349ca22d1319304d67b0 679 PANTHER PTHR23115 9 181 2.2E-219 T 22-04-2016 L21SP4_RS08680 9b6224e7f0a6349ca22d1319304d67b0 679 SUPERFAMILY SSF50447 251 384 1.74E-26 T 22-04-2016 IPR009000 Translation protein, beta-barrel domain L21SP4_RS08680 9b6224e7f0a6349ca22d1319304d67b0 679 PRINTS PR00315 GTP-binding elongation factor signature 82 92 3.61E-5 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 L21SP4_RS08680 9b6224e7f0a6349ca22d1319304d67b0 679 PRINTS PR00315 GTP-binding elongation factor signature 11 24 3.61E-5 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 L21SP4_RS08680 9b6224e7f0a6349ca22d1319304d67b0 679 PRINTS PR00315 GTP-binding elongation factor signature 98 109 3.61E-5 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 L21SP4_RS08680 9b6224e7f0a6349ca22d1319304d67b0 679 SUPERFAMILY SSF52540 6 268 1.01E-57 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS08680 9b6224e7f0a6349ca22d1319304d67b0 679 Pfam PF00679 Elongation factor G C-terminus 580 666 1.4E-29 T 22-04-2016 IPR000640 Translation elongation factor EFG, V domain L21SP4_RS08680 9b6224e7f0a6349ca22d1319304d67b0 679 SUPERFAMILY SSF54980 382 459 5.76E-18 T 22-04-2016 IPR009022 Elongation factor G, III-V domain L21SP4_RS08680 9b6224e7f0a6349ca22d1319304d67b0 679 Gene3D G3DSA:3.30.70.870 385 460 8.7E-24 T 22-04-2016 L21SP4_RS08680 9b6224e7f0a6349ca22d1319304d67b0 679 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 10 159 8.1E-17 T 22-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 L21SP4_RS08680 9b6224e7f0a6349ca22d1319304d67b0 679 SUPERFAMILY SSF54211 459 579 3.79E-40 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold L21SP4_RS08680 9b6224e7f0a6349ca22d1319304d67b0 679 Gene3D G3DSA:3.40.50.300 7 271 1.4E-50 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS08680 9b6224e7f0a6349ca22d1319304d67b0 679 Pfam PF03144 Elongation factor Tu domain 2 304 371 2.6E-8 T 22-04-2016 IPR004161 Translation elongation factor EFTu/EF1A, domain 2 GO:0005525 L21SP4_RS08680 9b6224e7f0a6349ca22d1319304d67b0 679 SMART SM00838 580 667 8.1E-44 T 22-04-2016 IPR000640 Translation elongation factor EFG, V domain L21SP4_RS08680 9b6224e7f0a6349ca22d1319304d67b0 679 Gene3D G3DSA:3.30.70.240 578 673 6.2E-33 T 22-04-2016 IPR000640 Translation elongation factor EFG, V domain L21SP4_RS08680 9b6224e7f0a6349ca22d1319304d67b0 679 PANTHER PTHR23115:SF98 241 671 2.2E-219 T 22-04-2016 L21SP4_RS08680 9b6224e7f0a6349ca22d1319304d67b0 679 PANTHER PTHR23115:SF98 9 181 2.2E-219 T 22-04-2016 L21SP4_RS08680 9b6224e7f0a6349ca22d1319304d67b0 679 Pfam PF00009 Elongation factor Tu GTP binding domain 8 267 8.0E-33 T 22-04-2016 L21SP4_RS08680 9b6224e7f0a6349ca22d1319304d67b0 679 Pfam PF14492 Elongation Factor G, domain II 384 455 1.0E-22 T 22-04-2016 IPR009022 Elongation factor G, III-V domain L21SP4_RS08680 9b6224e7f0a6349ca22d1319304d67b0 679 Pfam PF03764 Elongation factor G, domain IV 459 578 5.9E-39 T 22-04-2016 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 L21SP4_RS08680 9b6224e7f0a6349ca22d1319304d67b0 679 Gene3D G3DSA:3.30.230.10 464 577 6.7E-44 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup L21SP4_RS08680 9b6224e7f0a6349ca22d1319304d67b0 679 Gene3D G3DSA:2.40.30.10 286 384 1.2E-27 T 22-04-2016 L21SP4_RS08680 9b6224e7f0a6349ca22d1319304d67b0 679 SUPERFAMILY SSF54980 583 673 6.83E-30 T 22-04-2016 IPR009022 Elongation factor G, III-V domain L21SP4_RS05090 d536f185fb1af4cb5f8622dda3964791 480 Pfam PF08323 Starch synthase catalytic domain 2 242 1.3E-68 T 22-04-2016 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622|UniPathway: UPA00164 L21SP4_RS05090 d536f185fb1af4cb5f8622dda3964791 480 Hamap MF_00484 Glycogen synthase [glgA]. 1 480 38.842 T 22-04-2016 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622|UniPathway: UPA00164 L21SP4_RS05090 d536f185fb1af4cb5f8622dda3964791 480 Pfam PF00534 Glycosyl transferases group 1 298 444 6.6E-14 T 22-04-2016 IPR001296 Glycosyl transferase, family 1 L21SP4_RS05090 d536f185fb1af4cb5f8622dda3964791 480 Gene3D G3DSA:3.40.50.2000 256 462 1.8E-61 T 22-04-2016 L21SP4_RS05090 d536f185fb1af4cb5f8622dda3964791 480 TIGRFAM TIGR02095 glgA: glycogen/starch synthase, ADP-glucose type 1 480 1.4E-149 T 22-04-2016 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622|UniPathway: UPA00164 L21SP4_RS05090 d536f185fb1af4cb5f8622dda3964791 480 PANTHER PTHR12526 1 480 6.8E-119 T 22-04-2016 L21SP4_RS05090 d536f185fb1af4cb5f8622dda3964791 480 SUPERFAMILY SSF53756 2 480 1.26E-104 T 22-04-2016 L21SP4_RS05090 d536f185fb1af4cb5f8622dda3964791 480 PANTHER PTHR12526:SF17 1 480 6.8E-119 T 22-04-2016 L21SP4_RS08435 476052e219d0cc4b8f897051c1e1833d 1257 SUPERFAMILY SSF64484 4 214 0.0 T 22-04-2016 L21SP4_RS08435 476052e219d0cc4b8f897051c1e1833d 1257 SUPERFAMILY SSF64484 278 876 0.0 T 22-04-2016 L21SP4_RS08435 476052e219d0cc4b8f897051c1e1833d 1257 SUPERFAMILY SSF64484 995 1252 0.0 T 22-04-2016 L21SP4_RS08435 476052e219d0cc4b8f897051c1e1833d 1257 Pfam PF04561 RNA polymerase Rpb2, domain 2 273 387 2.9E-19 T 22-04-2016 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 L21SP4_RS08435 476052e219d0cc4b8f897051c1e1833d 1257 Pfam PF10385 RNA polymerase beta subunit external 1 domain 526 591 7.0E-24 T 22-04-2016 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 L21SP4_RS08435 476052e219d0cc4b8f897051c1e1833d 1257 Gene3D G3DSA:3.90.1100.10 378 526 3.7E-134 T 22-04-2016 L21SP4_RS08435 476052e219d0cc4b8f897051c1e1833d 1257 Gene3D G3DSA:3.90.1100.10 13 138 3.7E-134 T 22-04-2016 L21SP4_RS08435 476052e219d0cc4b8f897051c1e1833d 1257 Gene3D G3DSA:3.90.1100.10 594 646 3.7E-134 T 22-04-2016 L21SP4_RS08435 476052e219d0cc4b8f897051c1e1833d 1257 Gene3D G3DSA:3.90.1110.10 140 218 4.9E-51 T 22-04-2016 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 L21SP4_RS08435 476052e219d0cc4b8f897051c1e1833d 1257 Gene3D G3DSA:3.90.1110.10 281 377 4.9E-51 T 22-04-2016 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 L21SP4_RS08435 476052e219d0cc4b8f897051c1e1833d 1257 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 3 1249 0.0 T 22-04-2016 IPR010243 DNA-directed RNA polymerase, beta subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 L21SP4_RS08435 476052e219d0cc4b8f897051c1e1833d 1257 Gene3D G3DSA:2.30.150.10 527 591 1.5E-24 T 22-04-2016 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 L21SP4_RS08435 476052e219d0cc4b8f897051c1e1833d 1257 ProSitePatterns PS01166 RNA polymerases beta chain signature. 1019 1031 - T 22-04-2016 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 L21SP4_RS08435 476052e219d0cc4b8f897051c1e1833d 1257 Gene3D G3DSA:2.40.270.10 730 757 1.8E-74 T 22-04-2016 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 L21SP4_RS08435 476052e219d0cc4b8f897051c1e1833d 1257 Gene3D G3DSA:2.40.270.10 1016 1152 1.8E-74 T 22-04-2016 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 L21SP4_RS08435 476052e219d0cc4b8f897051c1e1833d 1257 Pfam PF04563 RNA polymerase beta subunit 19 434 4.2E-23 T 22-04-2016 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 L21SP4_RS08435 476052e219d0cc4b8f897051c1e1833d 1257 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 5 1252 12.007 T 22-04-2016 IPR010243 DNA-directed RNA polymerase, beta subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 L21SP4_RS08435 476052e219d0cc4b8f897051c1e1833d 1257 Gene3D G3DSA:2.40.50.150 764 874 7.1E-55 T 22-04-2016 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 L21SP4_RS08435 476052e219d0cc4b8f897051c1e1833d 1257 Gene3D G3DSA:2.40.50.150 1001 1015 7.1E-55 T 22-04-2016 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 L21SP4_RS08435 476052e219d0cc4b8f897051c1e1833d 1257 Pfam PF00562 RNA polymerase Rpb2, domain 6 652 1174 2.7E-155 T 22-04-2016 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 L21SP4_RS08435 476052e219d0cc4b8f897051c1e1833d 1257 Gene3D G3DSA:2.40.50.100 650 729 1.1E-24 T 22-04-2016 L21SP4_RS08435 476052e219d0cc4b8f897051c1e1833d 1257 Pfam PF04560 RNA polymerase Rpb2, domain 7 1176 1250 2.1E-24 T 22-04-2016 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 L21SP4_RS08435 476052e219d0cc4b8f897051c1e1833d 1257 PANTHER PTHR20856:SF20 275 660 0.0 T 22-04-2016 L21SP4_RS08435 476052e219d0cc4b8f897051c1e1833d 1257 PANTHER PTHR20856:SF20 680 867 0.0 T 22-04-2016 L21SP4_RS08435 476052e219d0cc4b8f897051c1e1833d 1257 PANTHER PTHR20856:SF20 990 1256 0.0 T 22-04-2016 L21SP4_RS08435 476052e219d0cc4b8f897051c1e1833d 1257 PANTHER PTHR20856:SF20 3 218 0.0 T 22-04-2016 L21SP4_RS08435 476052e219d0cc4b8f897051c1e1833d 1257 Pfam PF04565 RNA polymerase Rpb2, domain 3 448 516 1.2E-30 T 22-04-2016 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 L21SP4_RS08435 476052e219d0cc4b8f897051c1e1833d 1257 PANTHER PTHR20856 275 660 0.0 T 22-04-2016 IPR015712 DNA-directed RNA polymerase, subunit 2 GO:0003899|GO:0006351|GO:0032549 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 L21SP4_RS08435 476052e219d0cc4b8f897051c1e1833d 1257 PANTHER PTHR20856 680 867 0.0 T 22-04-2016 IPR015712 DNA-directed RNA polymerase, subunit 2 GO:0003899|GO:0006351|GO:0032549 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 L21SP4_RS08435 476052e219d0cc4b8f897051c1e1833d 1257 PANTHER PTHR20856 990 1256 0.0 T 22-04-2016 IPR015712 DNA-directed RNA polymerase, subunit 2 GO:0003899|GO:0006351|GO:0032549 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 L21SP4_RS08435 476052e219d0cc4b8f897051c1e1833d 1257 PANTHER PTHR20856 3 218 0.0 T 22-04-2016 IPR015712 DNA-directed RNA polymerase, subunit 2 GO:0003899|GO:0006351|GO:0032549 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 L21SP4_RS01980 5c59eb8b33f578842f647d8396a159ed 437 PRINTS PR00688 Xylose isomerase signature 334 345 3.6E-80 T 22-04-2016 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 L21SP4_RS01980 5c59eb8b33f578842f647d8396a159ed 437 PRINTS PR00688 Xylose isomerase signature 92 114 3.6E-80 T 22-04-2016 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 L21SP4_RS01980 5c59eb8b33f578842f647d8396a159ed 437 PRINTS PR00688 Xylose isomerase signature 230 254 3.6E-80 T 22-04-2016 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 L21SP4_RS01980 5c59eb8b33f578842f647d8396a159ed 437 PRINTS PR00688 Xylose isomerase signature 157 176 3.6E-80 T 22-04-2016 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 L21SP4_RS01980 5c59eb8b33f578842f647d8396a159ed 437 PRINTS PR00688 Xylose isomerase signature 181 202 3.6E-80 T 22-04-2016 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 L21SP4_RS01980 5c59eb8b33f578842f647d8396a159ed 437 PRINTS PR00688 Xylose isomerase signature 208 227 3.6E-80 T 22-04-2016 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 L21SP4_RS01980 5c59eb8b33f578842f647d8396a159ed 437 PRINTS PR00688 Xylose isomerase signature 134 154 3.6E-80 T 22-04-2016 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 L21SP4_RS01980 5c59eb8b33f578842f647d8396a159ed 437 PRINTS PR00688 Xylose isomerase signature 301 312 3.6E-80 T 22-04-2016 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 L21SP4_RS01980 5c59eb8b33f578842f647d8396a159ed 437 PRINTS PR00688 Xylose isomerase signature 272 299 3.6E-80 T 22-04-2016 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 L21SP4_RS01980 5c59eb8b33f578842f647d8396a159ed 437 PANTHER PTHR32176 4 437 4.5E-251 T 22-04-2016 L21SP4_RS01980 5c59eb8b33f578842f647d8396a159ed 437 PANTHER PTHR32176:SF0 4 437 4.5E-251 T 22-04-2016 L21SP4_RS01980 5c59eb8b33f578842f647d8396a159ed 437 SUPERFAMILY SSF51658 4 437 1.27E-159 T 22-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain L21SP4_RS01980 5c59eb8b33f578842f647d8396a159ed 437 TIGRFAM TIGR02630 xylose_isom_A: xylose isomerase 4 437 1.4E-205 T 22-04-2016 IPR013452 Xylose isomerase, bacterial-type GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 L21SP4_RS01980 5c59eb8b33f578842f647d8396a159ed 437 Gene3D G3DSA:3.20.20.150 3 437 2.6E-195 T 22-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain L21SP4_RS01980 5c59eb8b33f578842f647d8396a159ed 437 Hamap MF_00455 Xylose isomerase [xylA]. 11 437 50.807 T 22-04-2016 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 L21SP4_RS08670 97ce4bd9d9e90984c5bbe75331cc876d 481 SUPERFAMILY SSF51412 201 479 9.81E-124 T 22-04-2016 L21SP4_RS08670 97ce4bd9d9e90984c5bbe75331cc876d 481 SUPERFAMILY SSF51412 2 84 9.81E-124 T 22-04-2016 L21SP4_RS08670 97ce4bd9d9e90984c5bbe75331cc876d 481 Gene3D G3DSA:3.20.20.70 2 480 7.5E-168 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP4_RS08670 97ce4bd9d9e90984c5bbe75331cc876d 481 PANTHER PTHR11911:SF6 294 480 3.9E-197 T 22-04-2016 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: REACT_1698|UniPathway: UPA00601 L21SP4_RS08670 97ce4bd9d9e90984c5bbe75331cc876d 481 PANTHER PTHR11911:SF6 1 276 3.9E-197 T 22-04-2016 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: REACT_1698|UniPathway: UPA00601 L21SP4_RS08670 97ce4bd9d9e90984c5bbe75331cc876d 481 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 289 301 - T 22-04-2016 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 Reactome: REACT_1698 L21SP4_RS08670 97ce4bd9d9e90984c5bbe75331cc876d 481 PANTHER PTHR11911 294 480 3.9E-197 T 22-04-2016 L21SP4_RS08670 97ce4bd9d9e90984c5bbe75331cc876d 481 PANTHER PTHR11911 1 276 3.9E-197 T 22-04-2016 L21SP4_RS08670 97ce4bd9d9e90984c5bbe75331cc876d 481 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 2 448 5.5E-163 T 22-04-2016 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: REACT_1698|UniPathway: UPA00601 L21SP4_RS08670 97ce4bd9d9e90984c5bbe75331cc876d 481 SMART SM00116 90 140 0.043 T 22-04-2016 IPR000644 CBS domain L21SP4_RS08670 97ce4bd9d9e90984c5bbe75331cc876d 481 SMART SM00116 152 200 6.5E-8 T 22-04-2016 IPR000644 CBS domain L21SP4_RS08670 97ce4bd9d9e90984c5bbe75331cc876d 481 SUPERFAMILY SSF54631 89 201 2.44E-23 T 22-04-2016 L21SP4_RS08670 97ce4bd9d9e90984c5bbe75331cc876d 481 Pfam PF00571 CBS domain 145 196 2.0E-10 T 22-04-2016 IPR000644 CBS domain L21SP4_RS08670 97ce4bd9d9e90984c5bbe75331cc876d 481 Pfam PF00571 CBS domain 90 135 6.4E-4 T 22-04-2016 IPR000644 CBS domain L21SP4_RS08670 97ce4bd9d9e90984c5bbe75331cc876d 481 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 2 468 1.3E-142 T 22-04-2016 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 Reactome: REACT_1698 L21SP4_RS08670 97ce4bd9d9e90984c5bbe75331cc876d 481 SMART SM01240 1 468 2.1E-244 T 22-04-2016 L21SP4_RS08670 97ce4bd9d9e90984c5bbe75331cc876d 481 PIRSF PIRSF000130 1 481 3.1E-178 T 22-04-2016 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: REACT_1698|UniPathway: UPA00601 L21SP4_RS08670 97ce4bd9d9e90984c5bbe75331cc876d 481 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 2 481 70.708 T 22-04-2016 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: REACT_1698|UniPathway: UPA00601 L21SP4_RS09395 6506f029518f1bd0dd530a21527f81fb 440 Gene3D G3DSA:3.30.360.10 241 414 2.6E-15 T 22-04-2016 L21SP4_RS09395 6506f029518f1bd0dd530a21527f81fb 440 Gene3D G3DSA:3.30.360.10 190 203 2.6E-15 T 22-04-2016 L21SP4_RS09395 6506f029518f1bd0dd530a21527f81fb 440 PANTHER PTHR22604:SF122 3 423 5.3E-84 T 22-04-2016 L21SP4_RS09395 6506f029518f1bd0dd530a21527f81fb 440 SUPERFAMILY SSF55347 181 202 2.29E-13 T 22-04-2016 L21SP4_RS09395 6506f029518f1bd0dd530a21527f81fb 440 SUPERFAMILY SSF55347 237 341 2.29E-13 T 22-04-2016 L21SP4_RS09395 6506f029518f1bd0dd530a21527f81fb 440 Gene3D G3DSA:3.40.50.720 36 189 1.4E-41 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS09395 6506f029518f1bd0dd530a21527f81fb 440 PANTHER PTHR22604 3 423 5.3E-84 T 22-04-2016 L21SP4_RS09395 6506f029518f1bd0dd530a21527f81fb 440 SUPERFAMILY SSF51735 32 201 6.67E-40 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS09395 6506f029518f1bd0dd530a21527f81fb 440 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 42 169 5.8E-16 T 22-04-2016 IPR000683 Oxidoreductase, N-terminal GO:0016491 L21SP4_RS03720 438e429426875c35496b0fb2ccecd0ea 234 PANTHER PTHR30093:SF2 1 39 3.9E-13 T 22-04-2016 L21SP4_RS03720 438e429426875c35496b0fb2ccecd0ea 234 PANTHER PTHR30093 1 39 3.9E-13 T 22-04-2016 L21SP4_RS03720 438e429426875c35496b0fb2ccecd0ea 234 SUPERFAMILY SSF54523 13 97 1.41E-14 T 22-04-2016 L21SP4_RS03720 438e429426875c35496b0fb2ccecd0ea 234 Pfam PF13633 Prokaryotic N-terminal methylation site 10 35 1.5E-10 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site L21SP4_RS03720 438e429426875c35496b0fb2ccecd0ea 234 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 10 32 1.4E-9 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site L21SP4_RS03720 438e429426875c35496b0fb2ccecd0ea 234 Gene3D G3DSA:3.30.700.10 13 68 5.7E-11 T 22-04-2016 L21SP4_RS03720 438e429426875c35496b0fb2ccecd0ea 234 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 11 31 - T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site L21SP4_RS11070 a7f97ae6c26956895a34c53320cef574 243 Gene3D G3DSA:3.40.50.720 2 231 6.4E-44 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS11070 a7f97ae6c26956895a34c53320cef574 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 9.25E-16 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS11070 a7f97ae6c26956895a34c53320cef574 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 9.25E-16 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS11070 a7f97ae6c26956895a34c53320cef574 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 192 212 9.25E-16 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS11070 a7f97ae6c26956895a34c53320cef574 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 9.25E-16 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS11070 a7f97ae6c26956895a34c53320cef574 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 9.25E-16 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS11070 a7f97ae6c26956895a34c53320cef574 243 Pfam PF00106 short chain dehydrogenase 2 187 1.3E-28 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS11070 a7f97ae6c26956895a34c53320cef574 243 SUPERFAMILY SSF51735 2 241 1.84E-47 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS11070 a7f97ae6c26956895a34c53320cef574 243 PANTHER PTHR24322:SF333 148 179 2.1E-34 T 22-04-2016 L21SP4_RS11070 a7f97ae6c26956895a34c53320cef574 243 PANTHER PTHR24322:SF333 6 132 2.1E-34 T 22-04-2016 L21SP4_RS11070 a7f97ae6c26956895a34c53320cef574 243 PANTHER PTHR24322 148 179 2.1E-34 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS11070 a7f97ae6c26956895a34c53320cef574 243 PANTHER PTHR24322 6 132 2.1E-34 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS04750 ff344e529e72796fc2dbb8b3f3bf2b94 560 PRINTS PR00987 Glutamyl-tRNA synthetase signature 215 225 5.0E-9 T 22-04-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 L21SP4_RS04750 ff344e529e72796fc2dbb8b3f3bf2b94 560 PRINTS PR00987 Glutamyl-tRNA synthetase signature 36 48 5.0E-9 T 22-04-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 L21SP4_RS04750 ff344e529e72796fc2dbb8b3f3bf2b94 560 PRINTS PR00987 Glutamyl-tRNA synthetase signature 65 78 5.0E-9 T 22-04-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 L21SP4_RS04750 ff344e529e72796fc2dbb8b3f3bf2b94 560 Gene3D G3DSA:3.40.50.620 217 267 6.9E-45 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP4_RS04750 ff344e529e72796fc2dbb8b3f3bf2b94 560 Gene3D G3DSA:3.40.50.620 33 101 6.9E-45 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP4_RS04750 ff344e529e72796fc2dbb8b3f3bf2b94 560 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 33 342 9.8E-103 T 22-04-2016 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 Reactome: REACT_71 L21SP4_RS04750 ff344e529e72796fc2dbb8b3f3bf2b94 560 Hamap MF_00126 Glutamine--tRNA ligase [glnS]. 1 554 49.786 T 22-04-2016 IPR022861 Glutamine-tRNA ligase, bacterial GO:0004819 KEGG: 00970+6.1.1.18 L21SP4_RS04750 ff344e529e72796fc2dbb8b3f3bf2b94 560 SUPERFAMILY SSF52374 29 343 2.12E-95 T 22-04-2016 L21SP4_RS04750 ff344e529e72796fc2dbb8b3f3bf2b94 560 TIGRFAM TIGR00440 glnS: glutamine--tRNA ligase 33 556 6.3E-206 T 22-04-2016 IPR004514 Glutamine-tRNA synthetase GO:0000166|GO:0004819|GO:0005524|GO:0005737|GO:0006425 KEGG: 00970+6.1.1.18 L21SP4_RS04750 ff344e529e72796fc2dbb8b3f3bf2b94 560 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 39 50 - T 22-04-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 L21SP4_RS04750 ff344e529e72796fc2dbb8b3f3bf2b94 560 Gene3D G3DSA:3.90.800.10 106 214 7.7E-41 T 22-04-2016 L21SP4_RS04750 ff344e529e72796fc2dbb8b3f3bf2b94 560 Gene3D G3DSA:2.40.240.10 353 467 4.2E-39 T 22-04-2016 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: REACT_71 L21SP4_RS04750 ff344e529e72796fc2dbb8b3f3bf2b94 560 Gene3D G3DSA:2.40.240.10 468 552 5.1E-33 T 22-04-2016 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: REACT_71 L21SP4_RS04750 ff344e529e72796fc2dbb8b3f3bf2b94 560 PANTHER PTHR11451:SF29 30 252 6.7E-207 T 22-04-2016 L21SP4_RS04750 ff344e529e72796fc2dbb8b3f3bf2b94 560 PANTHER PTHR11451:SF29 272 558 6.7E-207 T 22-04-2016 L21SP4_RS04750 ff344e529e72796fc2dbb8b3f3bf2b94 560 Gene3D G3DSA:1.10.1160.10 268 342 2.6E-34 T 22-04-2016 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: REACT_71 L21SP4_RS04750 ff344e529e72796fc2dbb8b3f3bf2b94 560 Pfam PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain 345 534 1.6E-51 T 22-04-2016 IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 Reactome: REACT_71 L21SP4_RS04750 ff344e529e72796fc2dbb8b3f3bf2b94 560 SUPERFAMILY SSF50715 345 552 4.39E-66 T 22-04-2016 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: REACT_71 L21SP4_RS04750 ff344e529e72796fc2dbb8b3f3bf2b94 560 PANTHER PTHR11451 30 252 6.7E-207 T 22-04-2016 L21SP4_RS04750 ff344e529e72796fc2dbb8b3f3bf2b94 560 PANTHER PTHR11451 272 558 6.7E-207 T 22-04-2016 L21SP4_RS11485 fc0b38aed245bc38e4bfc79f19e35939 353 Pfam PF01008 Initiation factor 2 subunit family 49 338 5.4E-74 T 22-04-2016 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|UniPathway: UPA00904 L21SP4_RS11485 fc0b38aed245bc38e4bfc79f19e35939 353 Gene3D G3DSA:3.40.50.10470 162 343 5.8E-64 T 22-04-2016 L21SP4_RS11485 fc0b38aed245bc38e4bfc79f19e35939 353 Gene3D G3DSA:1.20.120.420 15 161 2.4E-47 T 22-04-2016 IPR027363 Methylthioribose-1-phosphate isomerase-like, N-terminal domain KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|UniPathway: UPA00904 L21SP4_RS11485 fc0b38aed245bc38e4bfc79f19e35939 353 SUPERFAMILY SSF100950 13 341 1.76E-112 T 22-04-2016 L21SP4_RS11485 fc0b38aed245bc38e4bfc79f19e35939 353 PANTHER PTHR10233 14 337 1.9E-143 T 22-04-2016 L21SP4_RS11485 fc0b38aed245bc38e4bfc79f19e35939 353 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 35 338 1.6E-100 T 22-04-2016 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|UniPathway: UPA00904 L21SP4_RS11485 fc0b38aed245bc38e4bfc79f19e35939 353 PANTHER PTHR10233:SF6 14 337 1.9E-143 T 22-04-2016 L21SP4_RS11485 fc0b38aed245bc38e4bfc79f19e35939 353 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 1 349 36.401 T 22-04-2016 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|UniPathway: UPA00904 L21SP4_RS11485 fc0b38aed245bc38e4bfc79f19e35939 353 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 15 340 4.9E-121 T 22-04-2016 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|UniPathway: UPA00904 L21SP4_RS05125 48c051e5fb4610f709dae9a007aabe92 327 TIGRFAM TIGR00433 bioB: biotin synthase 36 321 6.1E-107 T 22-04-2016 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380|UniPathway: UPA00078 L21SP4_RS05125 48c051e5fb4610f709dae9a007aabe92 327 Pfam PF04055 Radical SAM superfamily 66 220 4.9E-12 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 L21SP4_RS05125 48c051e5fb4610f709dae9a007aabe92 327 Gene3D G3DSA:3.20.20.70 31 324 3.5E-77 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP4_RS05125 48c051e5fb4610f709dae9a007aabe92 327 Hamap MF_01694 Biotin synthase [bioB]. 5 324 39.903 T 22-04-2016 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380|UniPathway: UPA00078 L21SP4_RS05125 48c051e5fb4610f709dae9a007aabe92 327 SUPERFAMILY SSF102114 31 324 1.31E-66 T 22-04-2016 L21SP4_RS05125 48c051e5fb4610f709dae9a007aabe92 327 SMART SM00729 57 264 9.2E-31 T 22-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 L21SP4_RS05125 48c051e5fb4610f709dae9a007aabe92 327 SMART SM00876 232 323 7.8E-33 T 22-04-2016 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380|UniPathway: UPA00078 L21SP4_RS05125 48c051e5fb4610f709dae9a007aabe92 327 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 232 321 7.7E-19 T 22-04-2016 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380|UniPathway: UPA00078 L21SP4_RS05125 48c051e5fb4610f709dae9a007aabe92 327 PIRSF PIRSF001619 1 326 1.6E-92 T 22-04-2016 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380|UniPathway: UPA00078 L21SP4_RS05125 48c051e5fb4610f709dae9a007aabe92 327 PANTHER PTHR22976:SF1 1 324 3.3E-109 T 22-04-2016 L21SP4_RS05125 48c051e5fb4610f709dae9a007aabe92 327 PANTHER PTHR22976 1 324 3.3E-109 T 22-04-2016 L21SP4_RS05570 d41d3e8d38046cbec134c9701e451b35 235 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 186 228 - T 22-04-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 L21SP4_RS05570 d41d3e8d38046cbec134c9701e451b35 235 SUPERFAMILY SSF55785 12 121 1.08E-13 T 22-04-2016 IPR000014 PAS domain L21SP4_RS05570 d41d3e8d38046cbec134c9701e451b35 235 Gene3D G3DSA:1.10.10.60 135 185 2.4E-15 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS05570 d41d3e8d38046cbec134c9701e451b35 235 SUPERFAMILY SSF46689 134 183 3.45E-10 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS05570 d41d3e8d38046cbec134c9701e451b35 235 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 20 126 1.6E-7 T 22-04-2016 IPR000014 PAS domain L21SP4_RS05570 d41d3e8d38046cbec134c9701e451b35 235 Pfam PF08448 PAS fold 17 125 1.4E-17 T 22-04-2016 IPR013656 PAS fold-4 L21SP4_RS05570 d41d3e8d38046cbec134c9701e451b35 235 Pfam PF12833 Helix-turn-helix domain 155 233 8.5E-26 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP4_RS05570 d41d3e8d38046cbec134c9701e451b35 235 PANTHER PTHR11019 132 235 6.9E-30 T 22-04-2016 L21SP4_RS05570 d41d3e8d38046cbec134c9701e451b35 235 Gene3D G3DSA:3.30.450.20 12 121 1.2E-12 T 22-04-2016 L21SP4_RS05570 d41d3e8d38046cbec134c9701e451b35 235 SUPERFAMILY SSF46689 185 233 2.46E-12 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS05570 d41d3e8d38046cbec134c9701e451b35 235 Gene3D G3DSA:1.10.10.60 186 233 1.1E-16 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS05570 d41d3e8d38046cbec134c9701e451b35 235 SMART SM00342 149 232 2.4E-28 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP4_RS06015 8cd3afeb353abfccdba564cb07fc3af6 169 PANTHER PTHR30093:SF3 12 77 5.5E-13 T 22-04-2016 L21SP4_RS06015 8cd3afeb353abfccdba564cb07fc3af6 169 SUPERFAMILY SSF54523 19 98 3.92E-14 T 22-04-2016 L21SP4_RS06015 8cd3afeb353abfccdba564cb07fc3af6 169 Gene3D G3DSA:3.30.700.10 19 74 5.7E-9 T 22-04-2016 L21SP4_RS06015 8cd3afeb353abfccdba564cb07fc3af6 169 PANTHER PTHR30093 12 77 5.5E-13 T 22-04-2016 L21SP4_RS06015 8cd3afeb353abfccdba564cb07fc3af6 169 Pfam PF13633 Prokaryotic N-terminal methylation site 17 41 1.7E-8 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site L21SP4_RS06015 8cd3afeb353abfccdba564cb07fc3af6 169 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 18 38 7.2E-7 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site L21SP4_RS00680 775d45c0d1b162f4a3671fb376a7ce90 501 ProSitePatterns PS00523 Sulfatases signature 1. 77 89 - T 22-04-2016 IPR024607 Sulfatase, conserved site L21SP4_RS00680 775d45c0d1b162f4a3671fb376a7ce90 501 PANTHER PTHR10342 4 472 1.5E-98 T 22-04-2016 L21SP4_RS00680 775d45c0d1b162f4a3671fb376a7ce90 501 Gene3D G3DSA:3.40.720.10 30 348 3.3E-77 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS00680 775d45c0d1b162f4a3671fb376a7ce90 501 Gene3D G3DSA:3.30.1120.10 428 477 1.4E-16 T 22-04-2016 L21SP4_RS00680 775d45c0d1b162f4a3671fb376a7ce90 501 Gene3D G3DSA:3.30.1120.10 363 391 1.4E-16 T 22-04-2016 L21SP4_RS00680 775d45c0d1b162f4a3671fb376a7ce90 501 Pfam PF00884 Sulfatase 32 329 5.4E-56 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS00680 775d45c0d1b162f4a3671fb376a7ce90 501 SUPERFAMILY SSF53649 29 476 1.15E-101 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS10795 da252f69f1422852ab492252ff4ccda1 376 Gene3D G3DSA:3.40.50.2300 187 360 2.5E-25 T 22-04-2016 L21SP4_RS10795 da252f69f1422852ab492252ff4ccda1 376 Gene3D G3DSA:3.40.50.2300 136 186 6.5E-6 T 22-04-2016 L21SP4_RS10795 da252f69f1422852ab492252ff4ccda1 376 Gene3D G3DSA:1.10.10.10 4 73 4.5E-22 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS10795 da252f69f1422852ab492252ff4ccda1 376 Pfam PF13377 Periplasmic binding protein-like domain 188 359 1.0E-18 T 22-04-2016 L21SP4_RS10795 da252f69f1422852ab492252ff4ccda1 376 SMART SM00345 12 71 3.1E-19 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 L21SP4_RS10795 da252f69f1422852ab492252ff4ccda1 376 SUPERFAMILY SSF53822 94 359 4.32E-26 T 22-04-2016 IPR028082 Periplasmic binding protein-like I L21SP4_RS10795 da252f69f1422852ab492252ff4ccda1 376 PANTHER PTHR30146 95 370 2.1E-19 T 22-04-2016 L21SP4_RS10795 da252f69f1422852ab492252ff4ccda1 376 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 71 1.3E-18 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 L21SP4_RS10795 da252f69f1422852ab492252ff4ccda1 376 SUPERFAMILY SSF46785 5 73 2.66E-19 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS10795 da252f69f1422852ab492252ff4ccda1 376 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 45 61 1.4E-9 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 L21SP4_RS10795 da252f69f1422852ab492252ff4ccda1 376 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 31 45 1.4E-9 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 L21SP4_RS06660 952ebbc383e5fed4264cf53b8ec73cbe 216 ProSitePatterns PS00856 Guanylate kinase-like signature. 51 68 - T 22-04-2016 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 L21SP4_RS06660 952ebbc383e5fed4264cf53b8ec73cbe 216 Gene3D G3DSA:3.30.63.10 59 98 4.9E-27 T 22-04-2016 L21SP4_RS06660 952ebbc383e5fed4264cf53b8ec73cbe 216 Pfam PF00625 Guanylate kinase 19 205 2.5E-45 T 22-04-2016 IPR008145 Guanylate kinase/L-type calcium channel beta subunit L21SP4_RS06660 952ebbc383e5fed4264cf53b8ec73cbe 216 SUPERFAMILY SSF52540 13 210 4.97E-63 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS06660 952ebbc383e5fed4264cf53b8ec73cbe 216 Gene3D G3DSA:3.40.50.300 99 211 5.2E-40 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS06660 952ebbc383e5fed4264cf53b8ec73cbe 216 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 18 205 8.0E-65 T 22-04-2016 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 L21SP4_RS06660 952ebbc383e5fed4264cf53b8ec73cbe 216 Hamap MF_00328 Guanylate kinase [gmk]. 15 208 34.527 T 22-04-2016 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 L21SP4_RS06660 952ebbc383e5fed4264cf53b8ec73cbe 216 SMART SM00072 16 208 2.3E-62 T 22-04-2016 IPR008145 Guanylate kinase/L-type calcium channel beta subunit L21SP4_RS06660 952ebbc383e5fed4264cf53b8ec73cbe 216 Gene3D G3DSA:3.40.50.300 14 58 1.4E-5 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS06660 952ebbc383e5fed4264cf53b8ec73cbe 216 PANTHER PTHR23117 6 210 7.9E-85 T 22-04-2016 L21SP4_RS06660 952ebbc383e5fed4264cf53b8ec73cbe 216 PANTHER PTHR23117:SF13 6 210 7.9E-85 T 22-04-2016 L21SP4_RS03850 33b985072cb771e7470c58e8ee1a25e1 109 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 3 94 8.4E-21 T 22-04-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 L21SP4_RS03850 33b985072cb771e7470c58e8ee1a25e1 109 SUPERFAMILY SSF69754 1 100 8.63E-25 T 22-04-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 L21SP4_RS03850 33b985072cb771e7470c58e8ee1a25e1 109 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 98 2.6E-23 T 22-04-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 L21SP4_RS03850 33b985072cb771e7470c58e8ee1a25e1 109 Gene3D G3DSA:3.30.160.100 1 95 4.1E-25 T 22-04-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 L21SP4_RS03850 33b985072cb771e7470c58e8ee1a25e1 109 PANTHER PTHR33231 1 105 6.8E-22 T 22-04-2016 L21SP4_RS05370 5a06ba41e86871fdca864c906f545aef 498 TIGRFAM TIGR01316 gltA: glutamate synthase (NADPH), homotetrameric 47 493 1.6E-184 T 22-04-2016 IPR006004 Glutamate synthase (NADPH), homotetrameric KEGG: 00195+1.18.1.2|MetaCyc: PWY-101|MetaCyc: PWY-7230 L21SP4_RS05370 5a06ba41e86871fdca864c906f545aef 498 PANTHER PTHR11938:SF90 48 497 4.4E-143 T 22-04-2016 L21SP4_RS05370 5a06ba41e86871fdca864c906f545aef 498 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 48 162 2.0E-39 T 22-04-2016 IPR028261 Dihydroprymidine dehydrogenase domain II L21SP4_RS05370 5a06ba41e86871fdca864c906f545aef 498 PANTHER PTHR11938 48 497 4.4E-143 T 22-04-2016 L21SP4_RS05370 5a06ba41e86871fdca864c906f545aef 498 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 317 342 6.5E-11 T 22-04-2016 L21SP4_RS05370 5a06ba41e86871fdca864c906f545aef 498 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 463 470 6.5E-11 T 22-04-2016 L21SP4_RS05370 5a06ba41e86871fdca864c906f545aef 498 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 421 435 6.5E-11 T 22-04-2016 L21SP4_RS05370 5a06ba41e86871fdca864c906f545aef 498 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 176 198 6.5E-11 T 22-04-2016 L21SP4_RS05370 5a06ba41e86871fdca864c906f545aef 498 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 448 470 3.7E-15 T 22-04-2016 L21SP4_RS05370 5a06ba41e86871fdca864c906f545aef 498 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 420 436 3.7E-15 T 22-04-2016 L21SP4_RS05370 5a06ba41e86871fdca864c906f545aef 498 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 177 196 3.7E-15 T 22-04-2016 L21SP4_RS05370 5a06ba41e86871fdca864c906f545aef 498 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 317 335 3.7E-15 T 22-04-2016 L21SP4_RS05370 5a06ba41e86871fdca864c906f545aef 498 Gene3D G3DSA:3.50.50.60 267 428 4.8E-50 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP4_RS05370 5a06ba41e86871fdca864c906f545aef 498 Gene3D G3DSA:1.10.1060.10 26 177 4.3E-44 T 22-04-2016 L21SP4_RS05370 5a06ba41e86871fdca864c906f545aef 498 Gene3D G3DSA:3.40.50.720 433 495 5.0E-23 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS05370 5a06ba41e86871fdca864c906f545aef 498 Gene3D G3DSA:3.40.50.720 178 266 5.0E-23 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS05370 5a06ba41e86871fdca864c906f545aef 498 SUPERFAMILY SSF51971 173 428 1.59E-61 T 22-04-2016 L21SP4_RS05370 5a06ba41e86871fdca864c906f545aef 498 SUPERFAMILY SSF46548 25 185 4.76E-35 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 L21SP4_RS05370 5a06ba41e86871fdca864c906f545aef 498 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 175 483 1.3E-35 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP4_RS09750 733c294bdf4a8f1eea992c54048fd3d5 178 SUPERFAMILY SSF53271 10 170 3.55E-41 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like L21SP4_RS09750 733c294bdf4a8f1eea992c54048fd3d5 178 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 10 178 31.785 T 22-04-2016 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|UniPathway: UPA00588 L21SP4_RS09750 733c294bdf4a8f1eea992c54048fd3d5 178 PANTHER PTHR32315 6 178 4.0E-68 T 22-04-2016 L21SP4_RS09750 733c294bdf4a8f1eea992c54048fd3d5 178 Gene3D G3DSA:3.40.50.2020 6 178 2.8E-58 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like L21SP4_RS09750 733c294bdf4a8f1eea992c54048fd3d5 178 Pfam PF00156 Phosphoribosyl transferase domain 31 140 1.9E-7 T 22-04-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 L21SP4_RS09750 733c294bdf4a8f1eea992c54048fd3d5 178 TIGRFAM TIGR01090 apt: adenine phosphoribosyltransferase 10 177 1.1E-60 T 22-04-2016 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|UniPathway: UPA00588 L21SP4_RS08960 f5d0c4d33d156033bd903bc8dd23553e 334 Gene3D G3DSA:2.60.120.280 68 214 1.3E-6 T 22-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 L21SP4_RS08960 f5d0c4d33d156033bd903bc8dd23553e 334 SUPERFAMILY SSF46689 283 333 2.55E-11 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS08960 f5d0c4d33d156033bd903bc8dd23553e 334 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 315 331 5.5E-7 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 L21SP4_RS08960 f5d0c4d33d156033bd903bc8dd23553e 334 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 300 315 5.5E-7 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 L21SP4_RS08960 f5d0c4d33d156033bd903bc8dd23553e 334 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 284 327 - T 22-04-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 L21SP4_RS08960 f5d0c4d33d156033bd903bc8dd23553e 334 Gene3D G3DSA:1.10.10.60 286 333 8.3E-17 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS08960 f5d0c4d33d156033bd903bc8dd23553e 334 Pfam PF12833 Helix-turn-helix domain 253 333 1.1E-21 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP4_RS08960 f5d0c4d33d156033bd903bc8dd23553e 334 SMART SM00342 247 331 8.9E-32 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP4_RS08960 f5d0c4d33d156033bd903bc8dd23553e 334 SUPERFAMILY SSF46689 236 280 4.93E-6 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS08960 f5d0c4d33d156033bd903bc8dd23553e 334 Gene3D G3DSA:1.10.10.60 237 285 4.8E-10 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS08960 f5d0c4d33d156033bd903bc8dd23553e 334 SUPERFAMILY SSF51182 59 158 2.4E-6 T 22-04-2016 IPR011051 RmlC-like cupin domain L21SP4_RS08960 f5d0c4d33d156033bd903bc8dd23553e 334 PANTHER PTHR11019 217 333 1.8E-30 T 22-04-2016 L21SP4_RS08960 f5d0c4d33d156033bd903bc8dd23553e 334 PANTHER PTHR11019 61 181 1.8E-30 T 22-04-2016 L21SP4_RS11550 37ff55215110831d31d0470a6f6f057c 428 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 428 181.948 T 22-04-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 L21SP4_RS11550 37ff55215110831d31d0470a6f6f057c 428 Pfam PF00709 Adenylosuccinate synthetase 4 419 7.8E-169 T 22-04-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 L21SP4_RS11550 37ff55215110831d31d0470a6f6f057c 428 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 22-04-2016 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 L21SP4_RS11550 37ff55215110831d31d0470a6f6f057c 428 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 5 422 9.5E-162 T 22-04-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 L21SP4_RS11550 37ff55215110831d31d0470a6f6f057c 428 Gene3D G3DSA:3.40.440.10 1 93 9.6E-69 T 22-04-2016 L21SP4_RS11550 37ff55215110831d31d0470a6f6f057c 428 Gene3D G3DSA:3.40.440.10 194 263 9.6E-69 T 22-04-2016 L21SP4_RS11550 37ff55215110831d31d0470a6f6f057c 428 PANTHER PTHR11846 2 425 5.0E-229 T 22-04-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 L21SP4_RS11550 37ff55215110831d31d0470a6f6f057c 428 SMART SM00788 3 421 5.1E-255 T 22-04-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 L21SP4_RS11550 37ff55215110831d31d0470a6f6f057c 428 SUPERFAMILY SSF52540 1 420 2.02E-161 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS11550 37ff55215110831d31d0470a6f6f057c 428 Gene3D G3DSA:3.90.170.10 264 421 3.4E-65 T 22-04-2016 L21SP4_RS11550 37ff55215110831d31d0470a6f6f057c 428 Gene3D G3DSA:1.10.300.10 101 193 7.3E-27 T 22-04-2016 L21SP4_RS11550 37ff55215110831d31d0470a6f6f057c 428 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 132 143 - T 22-04-2016 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|UniPathway: UPA00075 L21SP4_RS04175 bc489c848415dd2dd167c40157ea39b5 486 PANTHER PTHR10342:SF237 1 226 4.5E-168 T 22-04-2016 L21SP4_RS04175 bc489c848415dd2dd167c40157ea39b5 486 PANTHER PTHR10342:SF237 267 481 4.5E-168 T 22-04-2016 L21SP4_RS04175 bc489c848415dd2dd167c40157ea39b5 486 Pfam PF00884 Sulfatase 27 376 1.3E-61 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS04175 bc489c848415dd2dd167c40157ea39b5 486 Gene3D G3DSA:3.30.1120.10 405 481 8.4E-16 T 22-04-2016 L21SP4_RS04175 bc489c848415dd2dd167c40157ea39b5 486 Gene3D G3DSA:3.40.720.10 24 395 4.4E-118 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS04175 bc489c848415dd2dd167c40157ea39b5 486 PANTHER PTHR10342 1 226 4.5E-168 T 22-04-2016 L21SP4_RS04175 bc489c848415dd2dd167c40157ea39b5 486 PANTHER PTHR10342 267 481 4.5E-168 T 22-04-2016 L21SP4_RS04175 bc489c848415dd2dd167c40157ea39b5 486 ProSitePatterns PS00523 Sulfatases signature 1. 76 88 - T 22-04-2016 IPR024607 Sulfatase, conserved site L21SP4_RS04175 bc489c848415dd2dd167c40157ea39b5 486 SUPERFAMILY SSF53649 25 482 3.09E-128 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS04175 bc489c848415dd2dd167c40157ea39b5 486 Pfam PF16347 Domain of unknown function (DUF4976) 378 483 4.2E-40 T 22-04-2016 IPR032506 Domain of unknown function DUF4976 L21SP4_RS04210 3580e9416c1874b912faf9439d7589c3 175 Pfam PF10116 Protein required for attachment to host cells 6 151 1.0E-23 T 22-04-2016 IPR019291 Host attachment protein L21SP4_RS00940 1570b2baccf0058a729929fd73c55b33 320 Gene3D G3DSA:3.40.50.150 81 261 1.1E-35 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS00940 1570b2baccf0058a729929fd73c55b33 320 SUPERFAMILY SSF53335 33 283 1.98E-40 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS00940 1570b2baccf0058a729929fd73c55b33 320 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 100 253 1.1E-21 T 22-04-2016 IPR006342 Methyltransferase FkbM KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- L21SP4_RS00940 1570b2baccf0058a729929fd73c55b33 320 PANTHER PTHR34203 75 282 1.1E-18 T 22-04-2016 L21SP4_RS00940 1570b2baccf0058a729929fd73c55b33 320 Pfam PF05050 Methyltransferase FkbM domain 102 260 3.1E-17 T 22-04-2016 IPR006342 Methyltransferase FkbM KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- L21SP4_RS04345 2264d67dce510b86cd57cac20b79ce48 141 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 2 141 34.617 T 22-04-2016 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 L21SP4_RS04345 2264d67dce510b86cd57cac20b79ce48 141 Pfam PF07977 FabA-like domain 11 134 2.5E-40 T 22-04-2016 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 L21SP4_RS04345 2264d67dce510b86cd57cac20b79ce48 141 PANTHER PTHR30272 1 141 5.7E-71 T 22-04-2016 L21SP4_RS04345 2264d67dce510b86cd57cac20b79ce48 141 SUPERFAMILY SSF54637 5 139 1.24E-50 T 22-04-2016 IPR029069 HotDog domain L21SP4_RS04345 2264d67dce510b86cd57cac20b79ce48 141 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 2 138 2.3E-57 T 22-04-2016 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 L21SP4_RS04345 2264d67dce510b86cd57cac20b79ce48 141 Gene3D G3DSA:3.10.129.10 2 139 2.4E-57 T 22-04-2016 IPR029069 HotDog domain L21SP4_RS04285 16a0394c1f3e64e872da64760fab1b0a 180 PANTHER PTHR35011 1 160 2.7E-31 T 22-04-2016 L21SP4_RS04285 16a0394c1f3e64e872da64760fab1b0a 180 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 39 168 2.3E-30 T 22-04-2016 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component L21SP4_RS04285 16a0394c1f3e64e872da64760fab1b0a 180 PANTHER PTHR35011:SF2 1 160 2.7E-31 T 22-04-2016 L21SP4_RS05185 f22f89ad3a94dd5f29cafc5d357b3bb6 228 Gene3D G3DSA:3.20.20.10 3 227 1.5E-84 T 22-04-2016 IPR029066 PLP-binding barrel L21SP4_RS05185 f22f89ad3a94dd5f29cafc5d357b3bb6 228 PIRSF PIRSF004848 3 228 2.4E-71 T 22-04-2016 IPR011078 Uncharacterised protein family UPF0001 L21SP4_RS05185 f22f89ad3a94dd5f29cafc5d357b3bb6 228 Pfam PF01168 Alanine racemase, N-terminal domain 15 227 5.9E-25 T 22-04-2016 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 L21SP4_RS05185 f22f89ad3a94dd5f29cafc5d357b3bb6 228 SUPERFAMILY SSF51419 7 225 5.1E-71 T 22-04-2016 IPR029066 PLP-binding barrel L21SP4_RS05185 f22f89ad3a94dd5f29cafc5d357b3bb6 228 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 8 227 4.4E-53 T 22-04-2016 IPR011078 Uncharacterised protein family UPF0001 L21SP4_RS05185 f22f89ad3a94dd5f29cafc5d357b3bb6 228 PANTHER PTHR10146 6 227 3.7E-90 T 22-04-2016 IPR011078 Uncharacterised protein family UPF0001 L21SP4_RS10455 638e956ae74151943d3812785116fdd2 445 PANTHER PTHR23406 32 361 4.9E-187 T 22-04-2016 L21SP4_RS10455 638e956ae74151943d3812785116fdd2 445 PANTHER PTHR23406 388 425 4.9E-187 T 22-04-2016 L21SP4_RS10455 638e956ae74151943d3812785116fdd2 445 SUPERFAMILY SSF53223 11 168 7.19E-51 T 22-04-2016 L21SP4_RS10455 638e956ae74151943d3812785116fdd2 445 SMART SM01274 19 158 1.1E-75 T 22-04-2016 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 L21SP4_RS10455 638e956ae74151943d3812785116fdd2 445 PANTHER PTHR23406:SF23 32 361 4.9E-187 T 22-04-2016 L21SP4_RS10455 638e956ae74151943d3812785116fdd2 445 PANTHER PTHR23406:SF23 388 425 4.9E-187 T 22-04-2016 L21SP4_RS10455 638e956ae74151943d3812785116fdd2 445 Gene3D G3DSA:3.40.50.10380 6 167 2.4E-49 T 22-04-2016 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 L21SP4_RS10455 638e956ae74151943d3812785116fdd2 445 Pfam PF03949 Malic enzyme, NAD binding domain 172 366 3.7E-23 T 22-04-2016 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 L21SP4_RS10455 638e956ae74151943d3812785116fdd2 445 SMART SM00919 170 418 1.0E-121 T 22-04-2016 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 L21SP4_RS10455 638e956ae74151943d3812785116fdd2 445 Gene3D G3DSA:3.40.50.720 168 435 4.4E-83 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS10455 638e956ae74151943d3812785116fdd2 445 Pfam PF00390 Malic enzyme, N-terminal domain 20 158 4.3E-27 T 22-04-2016 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 L21SP4_RS10455 638e956ae74151943d3812785116fdd2 445 SUPERFAMILY SSF51735 170 363 2.9E-79 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS10455 638e956ae74151943d3812785116fdd2 445 SUPERFAMILY SSF51735 390 439 2.9E-79 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS10455 638e956ae74151943d3812785116fdd2 445 ProSitePatterns PS00331 Malic enzymes signature. 166 182 - T 22-04-2016 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 L21SP4_RS06760 3d59bda0946855595d9e5839974f3a5c 404 PIRSF PIRSF006392 1 398 5.6E-118 T 22-04-2016 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 L21SP4_RS06760 3d59bda0946855595d9e5839974f3a5c 404 Pfam PF01676 Metalloenzyme superfamily 1 360 1.2E-26 T 22-04-2016 IPR006124 Metalloenzyme GO:0003824|GO:0046872 L21SP4_RS06760 3d59bda0946855595d9e5839974f3a5c 404 PANTHER PTHR31209 1 374 1.3E-147 T 22-04-2016 L21SP4_RS06760 3d59bda0946855595d9e5839974f3a5c 404 Pfam PF10143 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 37 199 1.2E-53 T 22-04-2016 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 L21SP4_RS06760 3d59bda0946855595d9e5839974f3a5c 404 Gene3D G3DSA:3.40.720.10 187 359 3.5E-21 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS06760 3d59bda0946855595d9e5839974f3a5c 404 Gene3D G3DSA:3.40.720.10 2 80 3.5E-21 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS06760 3d59bda0946855595d9e5839974f3a5c 404 PANTHER PTHR31209:SF4 1 374 1.3E-147 T 22-04-2016 L21SP4_RS06760 3d59bda0946855595d9e5839974f3a5c 404 TIGRFAM TIGR02535 hyp_Hser_kinase: proposed homoserine kinase 1 377 1.3E-143 T 22-04-2016 IPR023665 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, prokaryotes GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 L21SP4_RS06760 3d59bda0946855595d9e5839974f3a5c 404 TIGRFAM TIGR00306 apgM: phosphoglycerate mutase (2,3-diphosphoglycerate-independent), archaeal form 4 393 1.2E-102 T 22-04-2016 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 L21SP4_RS06760 3d59bda0946855595d9e5839974f3a5c 404 SUPERFAMILY SSF53649 2 70 2.29E-24 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS06760 3d59bda0946855595d9e5839974f3a5c 404 SUPERFAMILY SSF53649 183 359 2.29E-24 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS05235 1eeb5545ec3e0e79c8f804de474575c3 224 SUPERFAMILY SSF53067 1 101 3.95E-12 T 22-04-2016 L21SP4_RS05235 1eeb5545ec3e0e79c8f804de474575c3 224 PANTHER PTHR11735 1 128 1.1E-15 T 22-04-2016 L21SP4_RS05235 1eeb5545ec3e0e79c8f804de474575c3 224 Pfam PF00814 Glycoprotease family 43 140 6.7E-8 T 22-04-2016 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 L21SP4_RS05235 1eeb5545ec3e0e79c8f804de474575c3 224 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 4 213 2.7E-30 T 22-04-2016 IPR022496 tRNA threonylcarbamoyl adenosine modification protein YeaZ GO:0002949 L21SP4_RS05235 1eeb5545ec3e0e79c8f804de474575c3 224 PANTHER PTHR11735:SF11 1 128 1.1E-15 T 22-04-2016 L21SP4_RS05235 1eeb5545ec3e0e79c8f804de474575c3 224 Gene3D G3DSA:3.30.420.40 1 129 2.6E-18 T 22-04-2016 L21SP4_RS05235 1eeb5545ec3e0e79c8f804de474575c3 224 SUPERFAMILY SSF53067 109 212 7.12E-8 T 22-04-2016 L21SP4_RS11985 611d9887be780b076310b76a44fbf93e 295 TIGRFAM TIGR02602 8TM_EpsH: exosortase 40 275 2.6E-35 T 22-04-2016 IPR013426 Exosortase, EpsH L21SP4_RS11985 611d9887be780b076310b76a44fbf93e 295 TIGRFAM TIGR04178 exo_archaeo: exosortase/archaeosortase family protein 188 281 2.4E-14 T 22-04-2016 IPR026392 Exosortase/Archaeosortase domain L21SP4_RS11985 611d9887be780b076310b76a44fbf93e 295 Pfam PF09721 Transmembrane exosortase (Exosortase_EpsH) 25 280 1.7E-40 T 22-04-2016 IPR019127 Exosortase EpsH-related KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- L21SP4_RS06525 6c5a3c90a831f67aaad03ccbee4c0b6b 956 SUPERFAMILY SSF49785 844 955 5.39E-7 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS06525 6c5a3c90a831f67aaad03ccbee4c0b6b 956 Gene3D G3DSA:2.60.120.260 844 956 2.3E-13 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS06525 6c5a3c90a831f67aaad03ccbee4c0b6b 956 Gene3D G3DSA:3.50.50.60 423 447 2.9E-23 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP4_RS06525 6c5a3c90a831f67aaad03ccbee4c0b6b 956 Gene3D G3DSA:3.50.50.60 216 355 2.9E-23 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP4_RS06525 6c5a3c90a831f67aaad03ccbee4c0b6b 956 Gene3D G3DSA:3.50.50.60 564 641 2.9E-23 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP4_RS06525 6c5a3c90a831f67aaad03ccbee4c0b6b 956 SUPERFAMILY SSF51905 215 404 1.33E-24 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP4_RS06525 6c5a3c90a831f67aaad03ccbee4c0b6b 956 SUPERFAMILY SSF51905 566 621 1.33E-24 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP4_RS06525 6c5a3c90a831f67aaad03ccbee4c0b6b 956 Pfam PF12831 FAD dependent oxidoreductase 219 639 1.6E-80 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP4_RS06525 6c5a3c90a831f67aaad03ccbee4c0b6b 956 PANTHER PTHR10668 176 259 2.0E-15 T 22-04-2016 L21SP4_RS06525 6c5a3c90a831f67aaad03ccbee4c0b6b 956 PANTHER PTHR10668:SF4 176 259 2.0E-15 T 22-04-2016 L21SP4_RS02040 0bcf4473206fda4b3cd7caac802f3370 779 Gene3D G3DSA:3.20.70.20 13 86 1.1E-138 T 22-04-2016 L21SP4_RS02040 0bcf4473206fda4b3cd7caac802f3370 779 Gene3D G3DSA:3.20.70.20 122 778 1.1E-138 T 22-04-2016 L21SP4_RS02040 0bcf4473206fda4b3cd7caac802f3370 779 PANTHER PTHR30191:SF6 180 778 3.2E-87 T 22-04-2016 L21SP4_RS02040 0bcf4473206fda4b3cd7caac802f3370 779 SUPERFAMILY SSF51998 18 95 1.42E-101 T 22-04-2016 L21SP4_RS02040 0bcf4473206fda4b3cd7caac802f3370 779 SUPERFAMILY SSF51998 129 779 1.42E-101 T 22-04-2016 L21SP4_RS02040 0bcf4473206fda4b3cd7caac802f3370 779 Pfam PF02901 Pyruvate formate lyase-like 13 623 8.1E-93 T 22-04-2016 IPR004184 Pyruvate formate lyase domain GO:0003824 L21SP4_RS02040 0bcf4473206fda4b3cd7caac802f3370 779 PANTHER PTHR30191 180 778 3.2E-87 T 22-04-2016 L21SP4_RS02040 0bcf4473206fda4b3cd7caac802f3370 779 Pfam PF01228 Glycine radical 662 763 1.6E-21 T 22-04-2016 IPR001150 Glycine radical domain GO:0003824|GO:0008152 L21SP4_RS09190 fbf6e746b56b3f1c7e8d7caa53433868 355 Gene3D G3DSA:3.40.47.10 187 354 1.6E-19 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 L21SP4_RS09190 fbf6e746b56b3f1c7e8d7caa53433868 355 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 274 353 1.5E-16 T 22-04-2016 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 L21SP4_RS09190 fbf6e746b56b3f1c7e8d7caa53433868 355 Gene3D G3DSA:3.40.47.10 13 186 3.8E-41 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 L21SP4_RS09190 fbf6e746b56b3f1c7e8d7caa53433868 355 PANTHER PTHR34069 8 355 1.2E-58 T 22-04-2016 L21SP4_RS09190 fbf6e746b56b3f1c7e8d7caa53433868 355 SUPERFAMILY SSF53901 13 195 9.99E-38 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 L21SP4_RS09190 fbf6e746b56b3f1c7e8d7caa53433868 355 PANTHER PTHR34069:SF2 8 355 1.2E-58 T 22-04-2016 L21SP4_RS09190 fbf6e746b56b3f1c7e8d7caa53433868 355 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 122 207 3.5E-16 T 22-04-2016 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 L21SP4_RS09190 fbf6e746b56b3f1c7e8d7caa53433868 355 SUPERFAMILY SSF53901 205 354 8.9E-16 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 L21SP4_RS07675 b747a23c770f0d12cdd9af168d099d67 383 PANTHER PTHR30489 1 383 6.0E-38 T 22-04-2016 L21SP4_RS07675 b747a23c770f0d12cdd9af168d099d67 383 Pfam PF12704 MacB-like periplasmic core domain 23 225 2.2E-13 T 22-04-2016 IPR025857 MacB-like periplasmic core domain L21SP4_RS07675 b747a23c770f0d12cdd9af168d099d67 383 Pfam PF02687 FtsX-like permease family 262 375 1.5E-10 T 22-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 L21SP4_RS03105 4ec49a7b09f4bd47c5853005c445b601 171 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 113 146 2.5E-7 T 22-04-2016 IPR001451 Hexapeptide repeat L21SP4_RS03105 4ec49a7b09f4bd47c5853005c445b601 171 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 122 150 - T 22-04-2016 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: REACT_17015 L21SP4_RS03105 4ec49a7b09f4bd47c5853005c445b601 171 PANTHER PTHR23416:SF53 46 87 8.6E-14 T 22-04-2016 L21SP4_RS03105 4ec49a7b09f4bd47c5853005c445b601 171 PANTHER PTHR23416:SF53 104 166 8.6E-14 T 22-04-2016 L21SP4_RS03105 4ec49a7b09f4bd47c5853005c445b601 171 PANTHER PTHR23416 46 87 8.6E-14 T 22-04-2016 L21SP4_RS03105 4ec49a7b09f4bd47c5853005c445b601 171 PANTHER PTHR23416 104 166 8.6E-14 T 22-04-2016 L21SP4_RS03105 4ec49a7b09f4bd47c5853005c445b601 171 Gene3D G3DSA:2.160.10.10 44 165 1.9E-25 T 22-04-2016 L21SP4_RS03105 4ec49a7b09f4bd47c5853005c445b601 171 SUPERFAMILY SSF51161 41 165 6.52E-26 T 22-04-2016 IPR011004 Trimeric LpxA-like L21SP4_RS11690 89f81432ef70b621042671ee22d69c34 412 Pfam PF13542 Helix-turn-helix domain of transposase family ISL3 94 140 1.8E-9 T 22-04-2016 IPR032877 Transposase IS204/IS1001/IS1096/IS1165, helix-turn-helix domain L21SP4_RS11690 89f81432ef70b621042671ee22d69c34 412 Pfam PF01610 Transposase 157 394 9.6E-78 T 22-04-2016 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain L21SP4_RS11690 89f81432ef70b621042671ee22d69c34 412 PANTHER PTHR33498:SF1 1 384 2.4E-51 T 22-04-2016 L21SP4_RS11690 89f81432ef70b621042671ee22d69c34 412 PANTHER PTHR33498 1 384 2.4E-51 T 22-04-2016 L21SP4_RS01055 64a1c2d28366f14e08a19c8178a3a04d 330 SUPERFAMILY SSF109998 27 198 6.38E-21 T 22-04-2016 IPR027304 Trigger factor/SurA domain L21SP4_RS01055 64a1c2d28366f14e08a19c8178a3a04d 330 PANTHER PTHR10657:SF11 8 328 7.1E-42 T 22-04-2016 L21SP4_RS01055 64a1c2d28366f14e08a19c8178a3a04d 330 SUPERFAMILY SSF54534 173 279 3.21E-18 T 22-04-2016 L21SP4_RS01055 64a1c2d28366f14e08a19c8178a3a04d 330 Pfam PF13624 SurA N-terminal domain 28 146 2.0E-10 T 22-04-2016 L21SP4_RS01055 64a1c2d28366f14e08a19c8178a3a04d 330 Pfam PF13145 PPIC-type PPIASE domain 161 290 5.9E-14 T 22-04-2016 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 L21SP4_RS01055 64a1c2d28366f14e08a19c8178a3a04d 330 PANTHER PTHR10657 8 328 7.1E-42 T 22-04-2016 L21SP4_RS01055 64a1c2d28366f14e08a19c8178a3a04d 330 Gene3D G3DSA:3.10.50.40 170 301 1.4E-26 T 22-04-2016 L21SP4_RS02785 13b04e5c887f672891c86b831bb15ad3 701 Pfam PF00702 haloacid dehalogenase-like hydrolase 382 600 1.7E-42 T 22-04-2016 L21SP4_RS02785 13b04e5c887f672891c86b831bb15ad3 701 PRINTS PR00943 Copper-transporting ATPase signature 307 321 4.3E-15 T 22-04-2016 L21SP4_RS02785 13b04e5c887f672891c86b831bb15ad3 701 PRINTS PR00943 Copper-transporting ATPase signature 154 173 4.3E-15 T 22-04-2016 L21SP4_RS02785 13b04e5c887f672891c86b831bb15ad3 701 PRINTS PR00943 Copper-transporting ATPase signature 563 580 4.3E-15 T 22-04-2016 L21SP4_RS02785 13b04e5c887f672891c86b831bb15ad3 701 PRINTS PR00943 Copper-transporting ATPase signature 97 116 4.3E-15 T 22-04-2016 L21SP4_RS02785 13b04e5c887f672891c86b831bb15ad3 701 PRINTS PR00943 Copper-transporting ATPase signature 369 384 4.3E-15 T 22-04-2016 L21SP4_RS02785 13b04e5c887f672891c86b831bb15ad3 701 SUPERFAMILY SSF56784 443 693 5.39E-57 T 22-04-2016 IPR023214 HAD-like domain L21SP4_RS02785 13b04e5c887f672891c86b831bb15ad3 701 SUPERFAMILY SSF56784 384 404 5.39E-57 T 22-04-2016 IPR023214 HAD-like domain L21SP4_RS02785 13b04e5c887f672891c86b831bb15ad3 701 SUPERFAMILY SSF81665 635 658 6.15E-15 T 22-04-2016 L21SP4_RS02785 13b04e5c887f672891c86b831bb15ad3 701 SUPERFAMILY SSF81665 145 188 6.15E-15 T 22-04-2016 L21SP4_RS02785 13b04e5c887f672891c86b831bb15ad3 701 SUPERFAMILY SSF81665 285 380 6.15E-15 T 22-04-2016 L21SP4_RS02785 13b04e5c887f672891c86b831bb15ad3 701 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 112 695 3.2E-193 T 22-04-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 L21SP4_RS02785 13b04e5c887f672891c86b831bb15ad3 701 Gene3D G3DSA:3.40.50.1000 514 654 1.3E-55 T 22-04-2016 IPR023214 HAD-like domain L21SP4_RS02785 13b04e5c887f672891c86b831bb15ad3 701 Gene3D G3DSA:3.40.50.1000 357 401 1.3E-55 T 22-04-2016 IPR023214 HAD-like domain L21SP4_RS02785 13b04e5c887f672891c86b831bb15ad3 701 Gene3D G3DSA:2.70.150.10 114 285 6.2E-31 T 22-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 L21SP4_RS02785 13b04e5c887f672891c86b831bb15ad3 701 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 234 248 2.0E-24 T 22-04-2016 L21SP4_RS02785 13b04e5c887f672891c86b831bb15ad3 701 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 386 400 2.0E-24 T 22-04-2016 L21SP4_RS02785 13b04e5c887f672891c86b831bb15ad3 701 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 533 543 2.0E-24 T 22-04-2016 L21SP4_RS02785 13b04e5c887f672891c86b831bb15ad3 701 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 609 621 2.0E-24 T 22-04-2016 L21SP4_RS02785 13b04e5c887f672891c86b831bb15ad3 701 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 586 605 2.0E-24 T 22-04-2016 L21SP4_RS02785 13b04e5c887f672891c86b831bb15ad3 701 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 94 696 1.2E-183 T 22-04-2016 L21SP4_RS02785 13b04e5c887f672891c86b831bb15ad3 701 PANTHER PTHR24093 37 697 1.3E-241 T 22-04-2016 L21SP4_RS02785 13b04e5c887f672891c86b831bb15ad3 701 SUPERFAMILY SSF81653 187 284 3.4E-28 T 22-04-2016 L21SP4_RS02785 13b04e5c887f672891c86b831bb15ad3 701 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 388 394 - T 22-04-2016 IPR018303 P-type ATPase, phosphorylation site L21SP4_RS02785 13b04e5c887f672891c86b831bb15ad3 701 Pfam PF00122 E1-E2 ATPase 155 377 1.3E-69 T 22-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 L21SP4_RS02785 13b04e5c887f672891c86b831bb15ad3 701 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 156 664 1.6E-88 T 22-04-2016 IPR001757 P-type ATPase GO:0016021 L21SP4_RS02785 13b04e5c887f672891c86b831bb15ad3 701 Gene3D G3DSA:3.40.1110.10 402 513 2.3E-21 T 22-04-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 L21SP4_RS02785 13b04e5c887f672891c86b831bb15ad3 701 PANTHER PTHR24093:SF50 37 697 1.3E-241 T 22-04-2016 L21SP4_RS11460 6a9b30e70a3fee73ccb9ffd79cc79558 830 SUPERFAMILY SSF48452 249 425 2.16E-12 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS11460 6a9b30e70a3fee73ccb9ffd79cc79558 830 SMART SM00028 504 537 0.97 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS11460 6a9b30e70a3fee73ccb9ffd79cc79558 830 SMART SM00028 732 765 300.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS11460 6a9b30e70a3fee73ccb9ffd79cc79558 830 SMART SM00028 393 426 8.8 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS11460 6a9b30e70a3fee73ccb9ffd79cc79558 830 SMART SM00028 778 811 330.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS11460 6a9b30e70a3fee73ccb9ffd79cc79558 830 SMART SM00028 467 500 54.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS11460 6a9b30e70a3fee73ccb9ffd79cc79558 830 SMART SM00028 578 611 110.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS11460 6a9b30e70a3fee73ccb9ffd79cc79558 830 SMART SM00028 541 574 11.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS11460 6a9b30e70a3fee73ccb9ffd79cc79558 830 SMART SM00028 321 354 2.5 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS11460 6a9b30e70a3fee73ccb9ffd79cc79558 830 SMART SM00028 356 389 15.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS11460 6a9b30e70a3fee73ccb9ffd79cc79558 830 SMART SM00028 652 685 1.2 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS11460 6a9b30e70a3fee73ccb9ffd79cc79558 830 PANTHER PTHR23083 280 806 3.7E-33 T 22-04-2016 L21SP4_RS11460 6a9b30e70a3fee73ccb9ffd79cc79558 830 PANTHER PTHR23083 83 111 3.7E-33 T 22-04-2016 L21SP4_RS11460 6a9b30e70a3fee73ccb9ffd79cc79558 830 Gene3D G3DSA:1.25.40.10 691 807 1.1E-4 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS11460 6a9b30e70a3fee73ccb9ffd79cc79558 830 SUPERFAMILY SSF48452 96 205 1.19E-6 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS11460 6a9b30e70a3fee73ccb9ffd79cc79558 830 SUPERFAMILY SSF48452 263 312 1.19E-6 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS11460 6a9b30e70a3fee73ccb9ffd79cc79558 830 Gene3D G3DSA:1.25.40.10 31 301 1.7E-9 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS11460 6a9b30e70a3fee73ccb9ffd79cc79558 830 Gene3D G3DSA:1.25.40.10 484 593 3.8E-17 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS11460 6a9b30e70a3fee73ccb9ffd79cc79558 830 Gene3D G3DSA:1.25.40.10 594 685 2.4E-14 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS11460 6a9b30e70a3fee73ccb9ffd79cc79558 830 Pfam PF13174 Tetratricopeptide repeat 582 607 0.16 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS11460 6a9b30e70a3fee73ccb9ffd79cc79558 830 Gene3D G3DSA:1.25.40.10 302 369 6.0E-7 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS11460 6a9b30e70a3fee73ccb9ffd79cc79558 830 SUPERFAMILY SSF48452 616 806 1.37E-14 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS11460 6a9b30e70a3fee73ccb9ffd79cc79558 830 Gene3D G3DSA:1.25.40.10 370 483 8.7E-16 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS11460 6a9b30e70a3fee73ccb9ffd79cc79558 830 Pfam PF13432 Tetratricopeptide repeat 173 221 0.0085 T 22-04-2016 L21SP4_RS11460 6a9b30e70a3fee73ccb9ffd79cc79558 830 Pfam PF13432 Tetratricopeptide repeat 510 574 2.4E-9 T 22-04-2016 L21SP4_RS11460 6a9b30e70a3fee73ccb9ffd79cc79558 830 Pfam PF13432 Tetratricopeptide repeat 622 685 3.2E-10 T 22-04-2016 L21SP4_RS11460 6a9b30e70a3fee73ccb9ffd79cc79558 830 Pfam PF13432 Tetratricopeptide repeat 439 500 5.3E-5 T 22-04-2016 L21SP4_RS11460 6a9b30e70a3fee73ccb9ffd79cc79558 830 Pfam PF13432 Tetratricopeptide repeat 360 425 6.4E-6 T 22-04-2016 L21SP4_RS11460 6a9b30e70a3fee73ccb9ffd79cc79558 830 SUPERFAMILY SSF48452 393 579 2.28E-26 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS06925 58ff0c72483dbc1348c84651f8cead20 308 SUPERFAMILY SSF55326 5 144 2.99E-30 T 22-04-2016 L21SP4_RS06925 58ff0c72483dbc1348c84651f8cead20 308 Gene3D G3DSA:3.90.650.10 151 172 9.9E-4 T 22-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain L21SP4_RS06925 58ff0c72483dbc1348c84651f8cead20 308 Gene3D G3DSA:3.90.650.10 174 301 1.8E-26 T 22-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain L21SP4_RS06925 58ff0c72483dbc1348c84651f8cead20 308 Pfam PF02769 AIR synthase related protein, C-terminal domain 189 283 4.5E-6 T 22-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain L21SP4_RS06925 58ff0c72483dbc1348c84651f8cead20 308 PANTHER PTHR30270:SF0 1 308 1.9E-75 T 22-04-2016 L21SP4_RS06925 58ff0c72483dbc1348c84651f8cead20 308 Gene3D G3DSA:3.30.1330.10 4 146 1.7E-38 T 22-04-2016 IPR016188 PurM-like, N-terminal domain L21SP4_RS06925 58ff0c72483dbc1348c84651f8cead20 308 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 10 301 1.9E-69 T 22-04-2016 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897|UniPathway: UPA00060 L21SP4_RS06925 58ff0c72483dbc1348c84651f8cead20 308 Pfam PF00586 AIR synthase related protein, N-terminal domain 33 143 3.5E-19 T 22-04-2016 IPR016188 PurM-like, N-terminal domain L21SP4_RS06925 58ff0c72483dbc1348c84651f8cead20 308 SUPERFAMILY SSF56042 150 284 2.27E-27 T 22-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain L21SP4_RS06925 58ff0c72483dbc1348c84651f8cead20 308 PANTHER PTHR30270 1 308 1.9E-75 T 22-04-2016 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897|UniPathway: UPA00060 L21SP4_RS06925 58ff0c72483dbc1348c84651f8cead20 308 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 8 298 26.704 T 22-04-2016 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897|UniPathway: UPA00060 L21SP4_RS06925 58ff0c72483dbc1348c84651f8cead20 308 PIRSF PIRSF005303 3 301 2.5E-73 T 22-04-2016 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897|UniPathway: UPA00060 L21SP4_RS06870 b01221564884528745381d6ddcca687b 225 PANTHER PTHR11080 8 220 6.7E-58 T 22-04-2016 L21SP4_RS06870 b01221564884528745381d6ddcca687b 225 PANTHER PTHR11080:SF2 8 220 6.7E-58 T 22-04-2016 L21SP4_RS06870 b01221564884528745381d6ddcca687b 225 Gene3D G3DSA:3.40.50.850 10 219 2.5E-57 T 22-04-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 L21SP4_RS06870 b01221564884528745381d6ddcca687b 225 SUPERFAMILY SSF52499 7 220 5.89E-42 T 22-04-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 L21SP4_RS06870 b01221564884528745381d6ddcca687b 225 Pfam PF00857 Isochorismatase family 12 216 3.9E-24 T 22-04-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 L21SP4_RS06185 b596884b4b6726f87592d8235facc057 84 Pfam PF02609 Exonuclease VII small subunit 14 65 9.0E-21 T 22-04-2016 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 L21SP4_RS06185 b596884b4b6726f87592d8235facc057 84 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 13 68 1.3E-21 T 22-04-2016 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 L21SP4_RS06185 b596884b4b6726f87592d8235facc057 84 SUPERFAMILY SSF116842 8 75 4.58E-19 T 22-04-2016 L21SP4_RS06185 b596884b4b6726f87592d8235facc057 84 Gene3D G3DSA:1.10.287.1040 10 79 3.5E-24 T 22-04-2016 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 L21SP4_RS06185 b596884b4b6726f87592d8235facc057 84 PANTHER PTHR34137 1 84 4.1E-17 T 22-04-2016 L21SP4_RS06185 b596884b4b6726f87592d8235facc057 84 PIRSF PIRSF006488 1 84 6.1E-21 T 22-04-2016 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 L21SP4_RS06185 b596884b4b6726f87592d8235facc057 84 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 14 52 2.0E-4 T 22-04-2016 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 L21SP4_RS06185 b596884b4b6726f87592d8235facc057 84 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 13 73 14.474 T 22-04-2016 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 L21SP4_RS08280 d693957c1481960462083511e9555cb2 135 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 20 132 1.1E-51 T 22-04-2016 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS08280 d693957c1481960462083511e9555cb2 135 Pfam PF00411 Ribosomal protein S11 25 134 1.3E-44 T 22-04-2016 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 L21SP4_RS08280 d693957c1481960462083511e9555cb2 135 PANTHER PTHR11759 22 135 3.7E-55 T 22-04-2016 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 L21SP4_RS08280 d693957c1481960462083511e9555cb2 135 PIRSF PIRSF002131 5 135 2.0E-47 T 22-04-2016 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 L21SP4_RS08280 d693957c1481960462083511e9555cb2 135 SUPERFAMILY SSF53137 21 135 2.22E-43 T 22-04-2016 L21SP4_RS08280 d693957c1481960462083511e9555cb2 135 Gene3D G3DSA:3.30.420.80 17 135 3.1E-48 T 22-04-2016 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 L21SP4_RS08280 d693957c1481960462083511e9555cb2 135 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 11 135 30.695 T 22-04-2016 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 L21SP4_RS03480 f6715e680b6c4d8c09d9e4e10b53b577 101 SUPERFAMILY SSF48295 1 61 3.24E-12 T 22-04-2016 IPR010921 Trp repressor/replication initiator GO:0043565 L21SP4_RS03480 f6715e680b6c4d8c09d9e4e10b53b577 101 Gene3D G3DSA:1.10.10.60 9 92 4.6E-6 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS03480 f6715e680b6c4d8c09d9e4e10b53b577 101 Pfam PF01527 Transposase 4 55 2.4E-8 T 22-04-2016 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 L21SP4_RS03480 f6715e680b6c4d8c09d9e4e10b53b577 101 PANTHER PTHR33215 1 58 1.6E-18 T 22-04-2016 L21SP4_RS03480 f6715e680b6c4d8c09d9e4e10b53b577 101 PANTHER PTHR33215:SF2 1 58 1.6E-18 T 22-04-2016 L21SP4_RS04490 f6715e680b6c4d8c09d9e4e10b53b577 101 SUPERFAMILY SSF48295 1 61 3.24E-12 T 22-04-2016 IPR010921 Trp repressor/replication initiator GO:0043565 L21SP4_RS04490 f6715e680b6c4d8c09d9e4e10b53b577 101 Gene3D G3DSA:1.10.10.60 9 92 4.6E-6 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS04490 f6715e680b6c4d8c09d9e4e10b53b577 101 Pfam PF01527 Transposase 4 55 2.4E-8 T 22-04-2016 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 L21SP4_RS04490 f6715e680b6c4d8c09d9e4e10b53b577 101 PANTHER PTHR33215 1 58 1.6E-18 T 22-04-2016 L21SP4_RS04490 f6715e680b6c4d8c09d9e4e10b53b577 101 PANTHER PTHR33215:SF2 1 58 1.6E-18 T 22-04-2016 L21SP4_RS07540 f6715e680b6c4d8c09d9e4e10b53b577 101 SUPERFAMILY SSF48295 1 61 3.24E-12 T 22-04-2016 IPR010921 Trp repressor/replication initiator GO:0043565 L21SP4_RS07540 f6715e680b6c4d8c09d9e4e10b53b577 101 Gene3D G3DSA:1.10.10.60 9 92 4.6E-6 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS07540 f6715e680b6c4d8c09d9e4e10b53b577 101 Pfam PF01527 Transposase 4 55 2.4E-8 T 22-04-2016 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 L21SP4_RS07540 f6715e680b6c4d8c09d9e4e10b53b577 101 PANTHER PTHR33215 1 58 1.6E-18 T 22-04-2016 L21SP4_RS07540 f6715e680b6c4d8c09d9e4e10b53b577 101 PANTHER PTHR33215:SF2 1 58 1.6E-18 T 22-04-2016 L21SP4_RS11730 f6715e680b6c4d8c09d9e4e10b53b577 101 SUPERFAMILY SSF48295 1 61 3.24E-12 T 22-04-2016 IPR010921 Trp repressor/replication initiator GO:0043565 L21SP4_RS11730 f6715e680b6c4d8c09d9e4e10b53b577 101 Gene3D G3DSA:1.10.10.60 9 92 4.6E-6 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS11730 f6715e680b6c4d8c09d9e4e10b53b577 101 Pfam PF01527 Transposase 4 55 2.4E-8 T 22-04-2016 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 L21SP4_RS11730 f6715e680b6c4d8c09d9e4e10b53b577 101 PANTHER PTHR33215 1 58 1.6E-18 T 22-04-2016 L21SP4_RS11730 f6715e680b6c4d8c09d9e4e10b53b577 101 PANTHER PTHR33215:SF2 1 58 1.6E-18 T 22-04-2016 L21SP4_RS10845 f6715e680b6c4d8c09d9e4e10b53b577 101 SUPERFAMILY SSF48295 1 61 3.24E-12 T 22-04-2016 IPR010921 Trp repressor/replication initiator GO:0043565 L21SP4_RS10845 f6715e680b6c4d8c09d9e4e10b53b577 101 Gene3D G3DSA:1.10.10.60 9 92 4.6E-6 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS10845 f6715e680b6c4d8c09d9e4e10b53b577 101 Pfam PF01527 Transposase 4 55 2.4E-8 T 22-04-2016 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 L21SP4_RS10845 f6715e680b6c4d8c09d9e4e10b53b577 101 PANTHER PTHR33215 1 58 1.6E-18 T 22-04-2016 L21SP4_RS10845 f6715e680b6c4d8c09d9e4e10b53b577 101 PANTHER PTHR33215:SF2 1 58 1.6E-18 T 22-04-2016 L21SP4_RS00200 09f8563a727c49963ff0efe376d9ae04 360 TIGRFAM TIGR00033 aroC: chorismate synthase 9 358 1.5E-144 T 22-04-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 L21SP4_RS00200 09f8563a727c49963ff0efe376d9ae04 360 Pfam PF01264 Chorismate synthase 9 354 7.4E-143 T 22-04-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 L21SP4_RS00200 09f8563a727c49963ff0efe376d9ae04 360 ProSitePatterns PS00788 Chorismate synthase signature 2. 123 139 - T 22-04-2016 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 L21SP4_RS00200 09f8563a727c49963ff0efe376d9ae04 360 ProSitePatterns PS00789 Chorismate synthase signature 3. 328 344 - T 22-04-2016 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 L21SP4_RS00200 09f8563a727c49963ff0efe376d9ae04 360 Gene3D G3DSA:3.60.150.10 8 358 1.7E-160 T 22-04-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 L21SP4_RS00200 09f8563a727c49963ff0efe376d9ae04 360 SUPERFAMILY SSF103263 3 358 1.96E-137 T 22-04-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 L21SP4_RS00200 09f8563a727c49963ff0efe376d9ae04 360 PIRSF PIRSF001456 2 360 6.1E-146 T 22-04-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 L21SP4_RS00200 09f8563a727c49963ff0efe376d9ae04 360 ProSitePatterns PS00787 Chorismate synthase signature 1. 15 30 - T 22-04-2016 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 L21SP4_RS00200 09f8563a727c49963ff0efe376d9ae04 360 PANTHER PTHR21085 1 359 1.1E-211 T 22-04-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 L21SP4_RS00200 09f8563a727c49963ff0efe376d9ae04 360 Hamap MF_00300 Chorismate synthase [aroC]. 9 360 37.159 T 22-04-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 L21SP4_RS00350 72d2155637f2cceb20cf67617d5c6a24 227 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 196 4.7E-30 T 22-04-2016 IPR023214 HAD-like domain L21SP4_RS00350 72d2155637f2cceb20cf67617d5c6a24 227 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 73 194 8.2E-10 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 L21SP4_RS00350 72d2155637f2cceb20cf67617d5c6a24 227 Gene3D G3DSA:3.40.50.1000 93 220 3.7E-33 T 22-04-2016 IPR023214 HAD-like domain L21SP4_RS00350 72d2155637f2cceb20cf67617d5c6a24 227 Gene3D G3DSA:3.40.50.1000 2 16 3.7E-33 T 22-04-2016 IPR023214 HAD-like domain L21SP4_RS00350 72d2155637f2cceb20cf67617d5c6a24 227 SUPERFAMILY SSF56784 1 220 6.07E-46 T 22-04-2016 IPR023214 HAD-like domain L21SP4_RS00350 72d2155637f2cceb20cf67617d5c6a24 227 Gene3D G3DSA:1.10.150.240 17 82 2.9E-6 T 22-04-2016 IPR023198 Phosphoglycolate phosphatase, domain 2 L21SP4_RS00350 72d2155637f2cceb20cf67617d5c6a24 227 PANTHER PTHR18901 4 220 8.7E-51 T 22-04-2016 L21SP4_RS11020 d2c4cc8da9855b419704a56683581121 1484 Pfam PF17132 alpha-L-rhamnosidase 39 905 1.7E-159 T 22-04-2016 IPR033400 Alpha-L-rhamnosidase RhaM L21SP4_RS11020 d2c4cc8da9855b419704a56683581121 1484 Pfam PF04616 Glycosyl hydrolases family 43 1227 1461 1.2E-18 T 22-04-2016 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 L21SP4_RS11020 d2c4cc8da9855b419704a56683581121 1484 Pfam PF04616 Glycosyl hydrolases family 43 1133 1192 1.5E-6 T 22-04-2016 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 L21SP4_RS11020 d2c4cc8da9855b419704a56683581121 1484 Gene3D G3DSA:2.115.10.20 1234 1470 1.1E-44 T 22-04-2016 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP4_RS11020 d2c4cc8da9855b419704a56683581121 1484 Gene3D G3DSA:2.115.10.20 1134 1201 1.1E-44 T 22-04-2016 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP4_RS11020 d2c4cc8da9855b419704a56683581121 1484 Gene3D G3DSA:2.60.120.260 211 318 1.0E-4 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS11020 d2c4cc8da9855b419704a56683581121 1484 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 968 1059 2.4E-6 T 22-04-2016 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP4_RS11020 d2c4cc8da9855b419704a56683581121 1484 PANTHER PTHR22925:SF40 1134 1199 3.5E-33 T 22-04-2016 L21SP4_RS11020 d2c4cc8da9855b419704a56683581121 1484 PANTHER PTHR22925:SF40 1237 1458 3.5E-33 T 22-04-2016 L21SP4_RS11020 d2c4cc8da9855b419704a56683581121 1484 SUPERFAMILY SSF49785 941 1067 3.04E-22 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS11020 d2c4cc8da9855b419704a56683581121 1484 Gene3D G3DSA:2.60.120.260 945 1061 1.5E-14 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS11020 d2c4cc8da9855b419704a56683581121 1484 SUPERFAMILY SSF75005 1134 1205 1.41E-39 T 22-04-2016 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP4_RS11020 d2c4cc8da9855b419704a56683581121 1484 SUPERFAMILY SSF75005 1234 1465 1.41E-39 T 22-04-2016 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP4_RS11020 d2c4cc8da9855b419704a56683581121 1484 PANTHER PTHR22925 1134 1199 3.5E-33 T 22-04-2016 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 L21SP4_RS11020 d2c4cc8da9855b419704a56683581121 1484 PANTHER PTHR22925 1237 1458 3.5E-33 T 22-04-2016 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 L21SP4_RS09700 fbbaf361caefc2252156ca8b0a01698b 324 Pfam PF14319 Transposase zinc-binding domain 34 148 1.1E-19 T 22-04-2016 IPR026889 Transposase zinc-binding domain L21SP4_RS09700 fbbaf361caefc2252156ca8b0a01698b 324 Pfam PF04986 Putative transposase 175 286 1.1E-12 T 22-04-2016 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 L21SP4_RS00700 467730f57342e9fc0994c4c136207d46 787 SUPERFAMILY SSF52518 375 589 1.18E-26 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold L21SP4_RS00700 467730f57342e9fc0994c4c136207d46 787 PANTHER PTHR31273 3 787 0.0 T 22-04-2016 L21SP4_RS00700 467730f57342e9fc0994c4c136207d46 787 PIRSF PIRSF017245 1 787 0.0 T 22-04-2016 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 L21SP4_RS00700 467730f57342e9fc0994c4c136207d46 787 PANTHER PTHR31273:SF0 3 787 0.0 T 22-04-2016 L21SP4_RS00700 467730f57342e9fc0994c4c136207d46 787 Pfam PF09363 XFP C-terminal domain 584 785 6.5E-94 T 22-04-2016 IPR018969 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, C-terminal GO:0005975|GO:0016832 L21SP4_RS00700 467730f57342e9fc0994c4c136207d46 787 SUPERFAMILY SSF52518 8 367 2.16E-69 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold L21SP4_RS00700 467730f57342e9fc0994c4c136207d46 787 Hamap MF_01403 Probable phosphoketolase. 4 787 41.207 T 22-04-2016 IPR023962 Probable phosphoketolase L21SP4_RS00700 467730f57342e9fc0994c4c136207d46 787 Pfam PF09364 XFP N-terminal domain 7 384 1.5E-183 T 22-04-2016 IPR018970 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, N-terminal L21SP4_RS00700 467730f57342e9fc0994c4c136207d46 787 ProSitePatterns PS60002 Phosphoketolase signature 1. 143 149 - T 22-04-2016 IPR019790 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, conserved site GO:0005975|GO:0016832 L21SP4_RS00700 467730f57342e9fc0994c4c136207d46 787 ProSitePatterns PS60003 Phosphoketolase signature 2. 156 174 - T 22-04-2016 IPR019789 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, thiamine diphosphate binding site GO:0005975|GO:0016832 L21SP4_RS00700 467730f57342e9fc0994c4c136207d46 787 Gene3D G3DSA:3.40.50.970 52 254 2.2E-15 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold L21SP4_RS00700 467730f57342e9fc0994c4c136207d46 787 Pfam PF03894 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase 398 573 5.5E-90 T 22-04-2016 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 L21SP4_RS01185 4e943c7728e39bdf4ae36414c8bce112 414 SUPERFAMILY SSF53901 216 413 1.98E-72 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 L21SP4_RS01185 4e943c7728e39bdf4ae36414c8bce112 414 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 156 172 - T 22-04-2016 IPR018201 Beta-ketoacyl synthase, active site L21SP4_RS01185 4e943c7728e39bdf4ae36414c8bce112 414 Gene3D G3DSA:3.40.47.10 264 413 5.8E-62 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 L21SP4_RS01185 4e943c7728e39bdf4ae36414c8bce112 414 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4 248 2.3E-62 T 22-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal L21SP4_RS01185 4e943c7728e39bdf4ae36414c8bce112 414 SMART SM00825 Beta-ketoacyl synthase 6 405 3.1E-16 T 22-04-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain L21SP4_RS01185 4e943c7728e39bdf4ae36414c8bce112 414 PANTHER PTHR11712 54 412 2.4E-205 T 22-04-2016 L21SP4_RS01185 4e943c7728e39bdf4ae36414c8bce112 414 PANTHER PTHR11712 1 38 2.4E-205 T 22-04-2016 L21SP4_RS01185 4e943c7728e39bdf4ae36414c8bce112 414 PIRSF PIRSF000447 1 414 9.2E-182 T 22-04-2016 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 UniPathway: UPA00094 L21SP4_RS01185 4e943c7728e39bdf4ae36414c8bce112 414 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 4 412 2.0E-192 T 22-04-2016 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 UniPathway: UPA00094 L21SP4_RS01185 4e943c7728e39bdf4ae36414c8bce112 414 Gene3D G3DSA:3.40.47.10 2 261 1.9E-77 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 L21SP4_RS01185 4e943c7728e39bdf4ae36414c8bce112 414 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 256 371 7.8E-38 T 22-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal L21SP4_RS01185 4e943c7728e39bdf4ae36414c8bce112 414 SUPERFAMILY SSF53901 4 253 2.27E-79 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 L21SP4_RS10765 5d50c64dc7a8345818008136619bd33b 493 ProSitePatterns PS00523 Sulfatases signature 1. 74 86 - T 22-04-2016 IPR024607 Sulfatase, conserved site L21SP4_RS10765 5d50c64dc7a8345818008136619bd33b 493 PANTHER PTHR10342 2 492 8.6E-133 T 22-04-2016 L21SP4_RS10765 5d50c64dc7a8345818008136619bd33b 493 Pfam PF00884 Sulfatase 28 366 4.1E-66 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS10765 5d50c64dc7a8345818008136619bd33b 493 SUPERFAMILY SSF53649 25 473 2.04E-116 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS10765 5d50c64dc7a8345818008136619bd33b 493 Gene3D G3DSA:3.40.720.10 25 387 1.4E-100 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS10765 5d50c64dc7a8345818008136619bd33b 493 PANTHER PTHR10342:SF199 2 492 8.6E-133 T 22-04-2016 L21SP4_RS10765 5d50c64dc7a8345818008136619bd33b 493 Gene3D G3DSA:3.30.1120.10 409 478 1.6E-14 T 22-04-2016 L21SP4_RS04620 5c3afb827d8d7874a02f57b2d210d9f5 398 Gene3D G3DSA:2.160.20.10 12 210 1.3E-22 T 22-04-2016 IPR012334 Pectin lyase fold L21SP4_RS04620 5c3afb827d8d7874a02f57b2d210d9f5 398 Gene3D G3DSA:2.160.20.10 244 332 1.3E-22 T 22-04-2016 IPR012334 Pectin lyase fold L21SP4_RS04620 5c3afb827d8d7874a02f57b2d210d9f5 398 SUPERFAMILY SSF51126 14 367 1.26E-25 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor L21SP4_RS04620 5c3afb827d8d7874a02f57b2d210d9f5 398 Pfam PF12708 Pectate lyase superfamily protein 30 80 4.6E-12 T 22-04-2016 IPR024535 Pectate lyase superfamily protein L21SP4_RS08285 1c2baceded46acf364f94f4427952f6f 134 Gene3D G3DSA:4.10.910.10 73 119 6.2E-24 T 22-04-2016 IPR027437 30s ribosomal protein S13, C-terminal L21SP4_RS08285 1c2baceded46acf364f94f4427952f6f 134 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 120 28.084 T 22-04-2016 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS08285 1c2baceded46acf364f94f4427952f6f 134 ProSitePatterns PS00646 Ribosomal protein S13 signature. 88 101 - T 22-04-2016 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 L21SP4_RS08285 1c2baceded46acf364f94f4427952f6f 134 PANTHER PTHR10871 1 117 1.0E-51 T 22-04-2016 L21SP4_RS08285 1c2baceded46acf364f94f4427952f6f 134 PIRSF PIRSF002134 1 125 5.7E-45 T 22-04-2016 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS08285 1c2baceded46acf364f94f4427952f6f 134 Gene3D G3DSA:1.10.8.50 1 72 2.1E-27 T 22-04-2016 L21SP4_RS08285 1c2baceded46acf364f94f4427952f6f 134 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 115 5.4E-48 T 22-04-2016 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS08285 1c2baceded46acf364f94f4427952f6f 134 SUPERFAMILY SSF46946 3 118 5.5E-43 T 22-04-2016 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 L21SP4_RS08285 1c2baceded46acf364f94f4427952f6f 134 Pfam PF00416 Ribosomal protein S13/S18 3 109 4.7E-33 T 22-04-2016 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS11480 177cc04a388696d9b0aff1c386746d0e 459 Hamap MF_00195 GTPase Der [der]. 17 457 34.668 T 22-04-2016 IPR016484 GTP-binding protein EngA GO:0005525 L21SP4_RS11480 177cc04a388696d9b0aff1c386746d0e 459 PIRSF PIRSF006485 16 459 8.3E-144 T 22-04-2016 IPR016484 GTP-binding protein EngA GO:0005525 L21SP4_RS11480 177cc04a388696d9b0aff1c386746d0e 459 Pfam PF01926 50S ribosome-binding GTPase 20 139 1.7E-24 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 L21SP4_RS11480 177cc04a388696d9b0aff1c386746d0e 459 Pfam PF01926 50S ribosome-binding GTPase 194 316 2.5E-20 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 L21SP4_RS11480 177cc04a388696d9b0aff1c386746d0e 459 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 92 110 2.0E-5 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 L21SP4_RS11480 177cc04a388696d9b0aff1c386746d0e 459 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 20 40 2.0E-5 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 L21SP4_RS11480 177cc04a388696d9b0aff1c386746d0e 459 PANTHER PTHR11649:SF5 17 453 1.6E-111 T 22-04-2016 IPR016484 GTP-binding protein EngA GO:0005525 L21SP4_RS11480 177cc04a388696d9b0aff1c386746d0e 459 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 193 357 5.0E-23 T 22-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 L21SP4_RS11480 177cc04a388696d9b0aff1c386746d0e 459 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 19 177 3.0E-22 T 22-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 L21SP4_RS11480 177cc04a388696d9b0aff1c386746d0e 459 SUPERFAMILY SSF52540 159 456 8.77E-56 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS11480 177cc04a388696d9b0aff1c386746d0e 459 SUPERFAMILY SSF52540 19 187 7.16E-42 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS11480 177cc04a388696d9b0aff1c386746d0e 459 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 375 453 4.7E-26 T 22-04-2016 IPR032859 GTPase Der, C-terminal KH-domain-like L21SP4_RS11480 177cc04a388696d9b0aff1c386746d0e 459 PANTHER PTHR11649 17 453 1.6E-111 T 22-04-2016 L21SP4_RS11480 177cc04a388696d9b0aff1c386746d0e 459 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 19 453 6.3E-145 T 22-04-2016 IPR016484 GTP-binding protein EngA GO:0005525 L21SP4_RS11480 177cc04a388696d9b0aff1c386746d0e 459 Gene3D G3DSA:3.40.50.300 18 189 1.8E-42 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS11480 177cc04a388696d9b0aff1c386746d0e 459 Gene3D G3DSA:3.40.50.300 190 379 1.5E-44 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS11480 177cc04a388696d9b0aff1c386746d0e 459 Gene3D G3DSA:3.30.300.20 380 455 1.3E-26 T 22-04-2016 IPR015946 K homology domain-like, alpha/beta L21SP4_RS09455 03c01aea8a09f1c81b164f5419753975 481 Gene3D G3DSA:3.40.720.10 19 382 2.5E-106 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS09455 03c01aea8a09f1c81b164f5419753975 481 PANTHER PTHR10342:SF199 1 481 5.9E-144 T 22-04-2016 L21SP4_RS09455 03c01aea8a09f1c81b164f5419753975 481 Gene3D G3DSA:3.30.1120.10 387 468 1.8E-20 T 22-04-2016 L21SP4_RS09455 03c01aea8a09f1c81b164f5419753975 481 Pfam PF16347 Domain of unknown function (DUF4976) 366 455 3.8E-7 T 22-04-2016 IPR032506 Domain of unknown function DUF4976 L21SP4_RS09455 03c01aea8a09f1c81b164f5419753975 481 SUPERFAMILY SSF53649 20 463 2.76E-127 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS09455 03c01aea8a09f1c81b164f5419753975 481 PANTHER PTHR10342 1 481 5.9E-144 T 22-04-2016 L21SP4_RS09455 03c01aea8a09f1c81b164f5419753975 481 Pfam PF00884 Sulfatase 21 363 1.9E-71 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS07860 08b07ef532f5253954ce3b3e813a62ba 169 PANTHER PTHR19384:SF73 1 119 3.6E-34 T 22-04-2016 L21SP4_RS07860 08b07ef532f5253954ce3b3e813a62ba 169 PANTHER PTHR19384:SF73 139 166 3.6E-34 T 22-04-2016 L21SP4_RS07860 08b07ef532f5253954ce3b3e813a62ba 169 SUPERFAMILY SSF52218 2 167 2.95E-43 T 22-04-2016 IPR029039 Flavoprotein-like domain L21SP4_RS07860 08b07ef532f5253954ce3b3e813a62ba 169 Gene3D G3DSA:3.40.50.360 1 166 7.1E-53 T 22-04-2016 IPR029039 Flavoprotein-like domain L21SP4_RS07860 08b07ef532f5253954ce3b3e813a62ba 169 PIRSF PIRSF038996 1 169 6.3E-58 T 22-04-2016 IPR010086 Flavodoxin, long chain GO:0010181 L21SP4_RS07860 08b07ef532f5253954ce3b3e813a62ba 169 Pfam PF00258 Flavodoxin 6 158 3.8E-23 T 22-04-2016 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 L21SP4_RS07860 08b07ef532f5253954ce3b3e813a62ba 169 TIGRFAM TIGR01752 flav_long: flavodoxin 3 166 3.5E-59 T 22-04-2016 IPR010086 Flavodoxin, long chain GO:0010181 L21SP4_RS07860 08b07ef532f5253954ce3b3e813a62ba 169 PANTHER PTHR19384 1 119 3.6E-34 T 22-04-2016 L21SP4_RS07860 08b07ef532f5253954ce3b3e813a62ba 169 PANTHER PTHR19384 139 166 3.6E-34 T 22-04-2016 L21SP4_RS07860 08b07ef532f5253954ce3b3e813a62ba 169 ProSitePatterns PS00201 Flavodoxin signature. 6 22 - T 22-04-2016 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 L21SP4_RS07860 08b07ef532f5253954ce3b3e813a62ba 169 PRINTS PR00369 Flavodoxin signature 79 89 1.4E-7 T 22-04-2016 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 L21SP4_RS07860 08b07ef532f5253954ce3b3e813a62ba 169 PRINTS PR00369 Flavodoxin signature 5 18 1.4E-7 T 22-04-2016 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 L21SP4_RS07860 08b07ef532f5253954ce3b3e813a62ba 169 PRINTS PR00369 Flavodoxin signature 50 61 1.4E-7 T 22-04-2016 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 L21SP4_RS11510 0e523897760cdd936dc1360c13dcff22 646 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 434 447 - T 22-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP4_RS11510 0e523897760cdd936dc1360c13dcff22 646 Gene3D G3DSA:1.10.10.10 573 643 7.1E-30 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS11510 0e523897760cdd936dc1360c13dcff22 646 PANTHER PTHR30603 97 245 9.6E-204 T 22-04-2016 L21SP4_RS11510 0e523897760cdd936dc1360c13dcff22 646 PANTHER PTHR30603 361 646 9.6E-204 T 22-04-2016 L21SP4_RS11510 0e523897760cdd936dc1360c13dcff22 646 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 603 629 - T 22-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP4_RS11510 0e523897760cdd936dc1360c13dcff22 646 Pfam PF04545 Sigma-70, region 4 579 631 4.8E-19 T 22-04-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP4_RS11510 0e523897760cdd936dc1360c13dcff22 646 PANTHER PTHR30603:SF0 97 245 9.6E-204 T 22-04-2016 L21SP4_RS11510 0e523897760cdd936dc1360c13dcff22 646 PANTHER PTHR30603:SF0 361 646 9.6E-204 T 22-04-2016 L21SP4_RS11510 0e523897760cdd936dc1360c13dcff22 646 Gene3D G3DSA:1.10.10.10 483 534 4.6E-26 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS11510 0e523897760cdd936dc1360c13dcff22 646 Pfam PF00140 Sigma-70 factor, region 1.2 191 220 1.1E-14 T 22-04-2016 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP4_RS11510 0e523897760cdd936dc1360c13dcff22 646 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 99 643 35.524 T 22-04-2016 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 L21SP4_RS11510 0e523897760cdd936dc1360c13dcff22 646 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 406 642 2.0E-120 T 22-04-2016 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 L21SP4_RS11510 0e523897760cdd936dc1360c13dcff22 646 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 407 631 1.2E-35 T 22-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP4_RS11510 0e523897760cdd936dc1360c13dcff22 646 PRINTS PR00046 Major sigma-70 factor signature 618 629 5.4E-30 T 22-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP4_RS11510 0e523897760cdd936dc1360c13dcff22 646 PRINTS PR00046 Major sigma-70 factor signature 582 594 5.4E-30 T 22-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP4_RS11510 0e523897760cdd936dc1360c13dcff22 646 PRINTS PR00046 Major sigma-70 factor signature 603 618 5.4E-30 T 22-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP4_RS11510 0e523897760cdd936dc1360c13dcff22 646 PRINTS PR00046 Major sigma-70 factor signature 458 466 5.4E-30 T 22-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP4_RS11510 0e523897760cdd936dc1360c13dcff22 646 PRINTS PR00046 Major sigma-70 factor signature 434 447 5.4E-30 T 22-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP4_RS11510 0e523897760cdd936dc1360c13dcff22 646 Pfam PF03979 Sigma-70 factor, region 1.1 110 182 1.5E-14 T 22-04-2016 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 L21SP4_RS11510 0e523897760cdd936dc1360c13dcff22 646 Pfam PF04542 Sigma-70 region 2 410 479 2.2E-21 T 22-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP4_RS11510 0e523897760cdd936dc1360c13dcff22 646 Gene3D G3DSA:1.10.601.10 214 479 3.6E-75 T 22-04-2016 L21SP4_RS11510 0e523897760cdd936dc1360c13dcff22 646 Gene3D G3DSA:1.10.601.10 30 213 6.4E-6 T 22-04-2016 L21SP4_RS11510 0e523897760cdd936dc1360c13dcff22 646 SUPERFAMILY SSF88659 541 633 5.23E-26 T 22-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP4_RS11510 0e523897760cdd936dc1360c13dcff22 646 Pfam PF04539 Sigma-70 region 3 489 565 4.2E-29 T 22-04-2016 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP4_RS11510 0e523897760cdd936dc1360c13dcff22 646 SUPERFAMILY SSF88659 483 556 4.42E-22 T 22-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP4_RS11510 0e523897760cdd936dc1360c13dcff22 646 SUPERFAMILY SSF88946 208 477 3.3E-62 T 22-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP4_RS00120 8478f062c8905551af00a3e0f60e9c6e 69 Hamap MF_00501 50S ribosomal protein L31 [rpmE]. 1 67 27.061 T 22-04-2016 IPR027491 Ribosomal protein L31 type A GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS00120 8478f062c8905551af00a3e0f60e9c6e 69 SUPERFAMILY SSF143800 1 66 3.41E-24 T 22-04-2016 L21SP4_RS00120 8478f062c8905551af00a3e0f60e9c6e 69 PRINTS PR01249 Ribosomal protein L31 signature 2 19 3.7E-21 T 22-04-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS00120 8478f062c8905551af00a3e0f60e9c6e 69 PRINTS PR01249 Ribosomal protein L31 signature 30 45 3.7E-21 T 22-04-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS00120 8478f062c8905551af00a3e0f60e9c6e 69 PRINTS PR01249 Ribosomal protein L31 signature 45 63 3.7E-21 T 22-04-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS00120 8478f062c8905551af00a3e0f60e9c6e 69 Pfam PF01197 Ribosomal protein L31 1 64 6.6E-30 T 22-04-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS00120 8478f062c8905551af00a3e0f60e9c6e 69 PANTHER PTHR33280:SF2 1 64 1.3E-30 T 22-04-2016 L21SP4_RS00120 8478f062c8905551af00a3e0f60e9c6e 69 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 65 2.9E-29 T 22-04-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS00120 8478f062c8905551af00a3e0f60e9c6e 69 PANTHER PTHR33280 1 64 1.3E-30 T 22-04-2016 L21SP4_RS00705 bb033135a348fe964ba2fe29e2f6d82d 186 Pfam PF01161 Phosphatidylethanolamine-binding protein 49 183 9.8E-41 T 22-04-2016 IPR008914 Phosphatidylethanolamine-binding protein L21SP4_RS00705 bb033135a348fe964ba2fe29e2f6d82d 186 Gene3D G3DSA:3.90.280.10 36 185 7.2E-59 T 22-04-2016 IPR008914 Phosphatidylethanolamine-binding protein L21SP4_RS00705 bb033135a348fe964ba2fe29e2f6d82d 186 PANTHER PTHR30289 20 185 5.6E-64 T 22-04-2016 L21SP4_RS00705 bb033135a348fe964ba2fe29e2f6d82d 186 SUPERFAMILY SSF49777 36 186 1.83E-51 T 22-04-2016 IPR008914 Phosphatidylethanolamine-binding protein L21SP4_RS00705 bb033135a348fe964ba2fe29e2f6d82d 186 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 54 181 1.4E-46 T 22-04-2016 IPR005247 YbhB/YbcL L21SP4_RS00355 6f24677773f006e809cc370a439646a6 969 Gene3D G3DSA:1.10.150.240 20 94 9.8E-25 T 22-04-2016 IPR023198 Phosphoglycolate phosphatase, domain 2 L21SP4_RS00355 6f24677773f006e809cc370a439646a6 969 SUPERFAMILY SSF48208 473 952 3.57E-118 T 22-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP4_RS00355 6f24677773f006e809cc370a439646a6 969 TIGRFAM TIGR02009 PGMB-YQAB-SF: beta-phosphoglucomutase family hydrolase 5 190 8.9E-56 T 22-04-2016 IPR010976 Beta-phosphoglucomutase hydrolase L21SP4_RS00355 6f24677773f006e809cc370a439646a6 969 TIGRFAM TIGR01990 bPGM: beta-phosphoglucomutase 5 191 1.3E-63 T 22-04-2016 IPR010972 Beta-phosphoglucomutase GO:0000287|GO:0005975|GO:0008801 KEGG: 00500+5.4.2.6|MetaCyc: PWY-2721|MetaCyc: PWY-2722|MetaCyc: PWY-6317|MetaCyc: PWY-7459 L21SP4_RS00355 6f24677773f006e809cc370a439646a6 969 Gene3D G3DSA:2.60.420.10 889 959 2.3E-24 T 22-04-2016 L21SP4_RS00355 6f24677773f006e809cc370a439646a6 969 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 75 190 5.7E-20 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 L21SP4_RS00355 6f24677773f006e809cc370a439646a6 969 Gene3D G3DSA:2.70.98.40 223 465 1.7E-48 T 22-04-2016 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 L21SP4_RS00355 6f24677773f006e809cc370a439646a6 969 SUPERFAMILY SSF74650 223 470 1.82E-40 T 22-04-2016 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 L21SP4_RS00355 6f24677773f006e809cc370a439646a6 969 Gene3D G3DSA:1.50.10.10 521 888 3.1E-123 T 22-04-2016 IPR012341 Six-hairpin glycosidase GO:0003824 L21SP4_RS00355 6f24677773f006e809cc370a439646a6 969 PANTHER PTHR11051 160 942 8.4E-149 T 22-04-2016 L21SP4_RS00355 6f24677773f006e809cc370a439646a6 969 Pfam PF03633 Glycosyl hydrolase family 65, C-terminal domain 907 957 1.3E-14 T 22-04-2016 IPR005194 Glycoside hydrolase family 65, C-terminal L21SP4_RS00355 6f24677773f006e809cc370a439646a6 969 Pfam PF13419 Haloacid dehalogenase-like hydrolase 8 190 3.0E-25 T 22-04-2016 IPR023214 HAD-like domain L21SP4_RS00355 6f24677773f006e809cc370a439646a6 969 SUPERFAMILY SSF56784 5 208 3.31E-50 T 22-04-2016 IPR023214 HAD-like domain L21SP4_RS00355 6f24677773f006e809cc370a439646a6 969 Gene3D G3DSA:3.40.50.1000 3 19 4.7E-39 T 22-04-2016 IPR023214 HAD-like domain L21SP4_RS00355 6f24677773f006e809cc370a439646a6 969 Gene3D G3DSA:3.40.50.1000 96 196 4.7E-39 T 22-04-2016 IPR023214 HAD-like domain L21SP4_RS00355 6f24677773f006e809cc370a439646a6 969 Pfam PF03636 Glycosyl hydrolase family 65, N-terminal domain 231 466 2.2E-39 T 22-04-2016 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 L21SP4_RS00355 6f24677773f006e809cc370a439646a6 969 Pfam PF03632 Glycosyl hydrolase family 65 central catalytic domain 525 900 3.2E-112 T 22-04-2016 IPR005195 Glycoside hydrolase, family 65, central catalytic GO:0003824|GO:0005975 L21SP4_RS06715 2cc91527bad3355aa7c702e4422f067d 455 PANTHER PTHR10342:SF199 1 454 1.6E-176 T 22-04-2016 L21SP4_RS06715 2cc91527bad3355aa7c702e4422f067d 455 SUPERFAMILY SSF53649 23 443 1.83E-136 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS06715 2cc91527bad3355aa7c702e4422f067d 455 Gene3D G3DSA:3.30.1120.10 390 451 1.4E-21 T 22-04-2016 L21SP4_RS06715 2cc91527bad3355aa7c702e4422f067d 455 Gene3D G3DSA:3.40.720.10 23 389 1.1E-120 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS06715 2cc91527bad3355aa7c702e4422f067d 455 Pfam PF00884 Sulfatase 25 354 1.8E-84 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS06715 2cc91527bad3355aa7c702e4422f067d 455 PANTHER PTHR10342 1 454 1.6E-176 T 22-04-2016 L21SP4_RS07200 8465cc3b9d4949372e54aa0a37fa67c8 453 Gene3D G3DSA:3.30.1120.10 390 445 3.1E-11 T 22-04-2016 L21SP4_RS07200 8465cc3b9d4949372e54aa0a37fa67c8 453 Pfam PF00884 Sulfatase 46 358 9.4E-48 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS07200 8465cc3b9d4949372e54aa0a37fa67c8 453 PANTHER PTHR10342:SF207 217 446 8.3E-85 T 22-04-2016 L21SP4_RS07200 8465cc3b9d4949372e54aa0a37fa67c8 453 PANTHER PTHR10342:SF207 17 201 8.3E-85 T 22-04-2016 L21SP4_RS07200 8465cc3b9d4949372e54aa0a37fa67c8 453 Gene3D G3DSA:3.40.720.10 43 376 3.0E-77 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS07200 8465cc3b9d4949372e54aa0a37fa67c8 453 PANTHER PTHR10342 217 446 8.3E-85 T 22-04-2016 L21SP4_RS07200 8465cc3b9d4949372e54aa0a37fa67c8 453 PANTHER PTHR10342 17 201 8.3E-85 T 22-04-2016 L21SP4_RS07200 8465cc3b9d4949372e54aa0a37fa67c8 453 SUPERFAMILY SSF53649 44 447 2.51E-99 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS03995 0972b248f647fd5d379408fa239320dd 694 Gene3D G3DSA:2.60.450.10 33 147 1.9E-13 T 22-04-2016 L21SP4_RS03995 0972b248f647fd5d379408fa239320dd 694 PANTHER PTHR30189 37 682 4.6E-13 T 22-04-2016 L21SP4_RS03995 0972b248f647fd5d379408fa239320dd 694 Pfam PF13100 OstA-like protein 48 102 1.8E-5 T 22-04-2016 IPR005653 Organic solvent tolerance-like, N-terminal L21SP4_RS03995 0972b248f647fd5d379408fa239320dd 694 Pfam PF04453 Organic solvent tolerance protein 279 618 2.3E-8 T 22-04-2016 IPR007543 Organic solvent tolerance protein, C-terminal GO:0010033|GO:0019867|GO:0061024 L21SP4_RS06820 c612e3ae6d35db5e1262185c7bcbf95e 236 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 8 226 3.0E-45 T 22-04-2016 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|UniPathway: UPA00070 L21SP4_RS06820 c612e3ae6d35db5e1262185c7bcbf95e 236 SUPERFAMILY SSF51366 6 230 1.7E-66 T 22-04-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 L21SP4_RS06820 c612e3ae6d35db5e1262185c7bcbf95e 236 Hamap MF_01200_B Orotidine 5'-phosphate decarboxylase [pyrF]. 6 232 35.27 T 22-04-2016 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|UniPathway: UPA00070 L21SP4_RS06820 c612e3ae6d35db5e1262185c7bcbf95e 236 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 9 227 2.4E-52 T 22-04-2016 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|UniPathway: UPA00070 L21SP4_RS06820 c612e3ae6d35db5e1262185c7bcbf95e 236 PANTHER PTHR32119:SF2 1 233 1.1E-86 T 22-04-2016 L21SP4_RS06820 c612e3ae6d35db5e1262185c7bcbf95e 236 Gene3D G3DSA:3.20.20.70 7 231 2.0E-76 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP4_RS06820 c612e3ae6d35db5e1262185c7bcbf95e 236 SMART SM00934 8 227 1.1E-81 T 22-04-2016 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|UniPathway: UPA00070 L21SP4_RS06820 c612e3ae6d35db5e1262185c7bcbf95e 236 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 60 73 - T 22-04-2016 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|UniPathway: UPA00070 L21SP4_RS06820 c612e3ae6d35db5e1262185c7bcbf95e 236 PANTHER PTHR32119 1 233 1.1E-86 T 22-04-2016 L21SP4_RS04425 91c772289dd7da69c9d43cd322c8292f 1187 PANTHER PTHR33307:SF5 21 659 7.3E-160 T 22-04-2016 L21SP4_RS04425 91c772289dd7da69c9d43cd322c8292f 1187 Pfam PF05592 Bacterial alpha-L-rhamnosidase 372 923 2.4E-93 T 22-04-2016 IPR008902 Bacterial alpha-L-rhamnosidase L21SP4_RS04425 91c772289dd7da69c9d43cd322c8292f 1187 PANTHER PTHR33307:SF5 684 931 7.3E-160 T 22-04-2016 L21SP4_RS04425 91c772289dd7da69c9d43cd322c8292f 1187 Gene3D G3DSA:2.60.120.260 360 462 3.8E-7 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS04425 91c772289dd7da69c9d43cd322c8292f 1187 Gene3D G3DSA:2.60.120.200 1034 1183 2.5E-7 T 22-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP4_RS04425 91c772289dd7da69c9d43cd322c8292f 1187 PANTHER PTHR33307 684 931 7.3E-160 T 22-04-2016 L21SP4_RS04425 91c772289dd7da69c9d43cd322c8292f 1187 Pfam PF08531 Alpha-L-rhamnosidase N-terminal domain 191 352 1.7E-37 T 22-04-2016 IPR013737 Bacterial alpha-L-rhamnosidase N-terminal L21SP4_RS04425 91c772289dd7da69c9d43cd322c8292f 1187 SUPERFAMILY SSF48208 475 649 1.5E-24 T 22-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP4_RS04425 91c772289dd7da69c9d43cd322c8292f 1187 SUPERFAMILY SSF48208 682 930 1.5E-24 T 22-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP4_RS04425 91c772289dd7da69c9d43cd322c8292f 1187 PANTHER PTHR33307 21 659 7.3E-160 T 22-04-2016 L21SP4_RS03250 ccd167f6bb1fa88d0c56d05875e0ee0c 1047 Pfam PF04851 Type III restriction enzyme, res subunit 259 416 3.8E-16 T 22-04-2016 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 L21SP4_RS03250 ccd167f6bb1fa88d0c56d05875e0ee0c 1047 Gene3D G3DSA:3.40.50.300 243 430 9.9E-19 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS03250 ccd167f6bb1fa88d0c56d05875e0ee0c 1047 SUPERFAMILY SSF52540 269 322 2.62E-6 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS03250 ccd167f6bb1fa88d0c56d05875e0ee0c 1047 SUPERFAMILY SSF52540 586 679 2.62E-6 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS03250 ccd167f6bb1fa88d0c56d05875e0ee0c 1047 SMART SM00487 245 453 4.7E-9 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain L21SP4_RS03250 ccd167f6bb1fa88d0c56d05875e0ee0c 1047 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 6 196 1.5E-34 T 22-04-2016 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 L21SP4_RS03250 ccd167f6bb1fa88d0c56d05875e0ee0c 1047 SUPERFAMILY SSF52540 212 451 4.0E-24 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS03250 ccd167f6bb1fa88d0c56d05875e0ee0c 1047 PANTHER PTHR30195:SF15 582 944 5.8E-107 T 22-04-2016 L21SP4_RS03250 ccd167f6bb1fa88d0c56d05875e0ee0c 1047 PANTHER PTHR30195:SF15 45 566 5.8E-107 T 22-04-2016 L21SP4_RS03250 ccd167f6bb1fa88d0c56d05875e0ee0c 1047 TIGRFAM TIGR00348 hsdR: type I site-specific deoxyribonuclease, HsdR family 11 693 9.9E-161 T 22-04-2016 IPR004473 Restriction endonuclease, type I, HsdR GO:0003677|GO:0005524|GO:0009035|GO:0009307 L21SP4_RS03250 ccd167f6bb1fa88d0c56d05875e0ee0c 1047 PANTHER PTHR30195 582 944 5.8E-107 T 22-04-2016 L21SP4_RS03250 ccd167f6bb1fa88d0c56d05875e0ee0c 1047 PANTHER PTHR30195 45 566 5.8E-107 T 22-04-2016 L21SP4_RS06730 151bcda2414c2a0c3388c735b05da448 569 Gene3D G3DSA:3.30.1120.10 467 548 5.8E-8 T 22-04-2016 L21SP4_RS06730 151bcda2414c2a0c3388c735b05da448 569 Pfam PF00884 Sulfatase 36 416 2.0E-64 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS06730 151bcda2414c2a0c3388c735b05da448 569 SUPERFAMILY SSF53649 35 59 7.56E-95 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS06730 151bcda2414c2a0c3388c735b05da448 569 SUPERFAMILY SSF53649 92 175 7.56E-95 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS06730 151bcda2414c2a0c3388c735b05da448 569 SUPERFAMILY SSF53649 219 536 7.56E-95 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS06730 151bcda2414c2a0c3388c735b05da448 569 PANTHER PTHR10342 218 449 2.2E-103 T 22-04-2016 L21SP4_RS06730 151bcda2414c2a0c3388c735b05da448 569 PANTHER PTHR10342 82 170 2.2E-103 T 22-04-2016 L21SP4_RS06730 151bcda2414c2a0c3388c735b05da448 569 PANTHER PTHR10342 8 49 2.2E-103 T 22-04-2016 L21SP4_RS06730 151bcda2414c2a0c3388c735b05da448 569 PANTHER PTHR10342 471 563 2.2E-103 T 22-04-2016 L21SP4_RS06730 151bcda2414c2a0c3388c735b05da448 569 PANTHER PTHR10342:SF199 218 449 2.2E-103 T 22-04-2016 L21SP4_RS06730 151bcda2414c2a0c3388c735b05da448 569 PANTHER PTHR10342:SF199 82 170 2.2E-103 T 22-04-2016 L21SP4_RS06730 151bcda2414c2a0c3388c735b05da448 569 PANTHER PTHR10342:SF199 8 49 2.2E-103 T 22-04-2016 L21SP4_RS06730 151bcda2414c2a0c3388c735b05da448 569 PANTHER PTHR10342:SF199 471 563 2.2E-103 T 22-04-2016 L21SP4_RS06730 151bcda2414c2a0c3388c735b05da448 569 ProSitePatterns PS00149 Sulfatases signature 2. 159 169 - T 22-04-2016 IPR024607 Sulfatase, conserved site L21SP4_RS06730 151bcda2414c2a0c3388c735b05da448 569 Gene3D G3DSA:3.40.720.10 92 175 2.1E-91 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS06730 151bcda2414c2a0c3388c735b05da448 569 Gene3D G3DSA:3.40.720.10 218 435 2.1E-91 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS06730 151bcda2414c2a0c3388c735b05da448 569 Gene3D G3DSA:3.40.720.10 35 59 2.1E-91 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS04310 8723f08c3aad62a1fb65f069dfd240fd 166 SUPERFAMILY SSF47240 2 126 2.76E-38 T 22-04-2016 IPR009078 Ferritin-like superfamily L21SP4_RS04310 8723f08c3aad62a1fb65f069dfd240fd 166 PANTHER PTHR33746:SF3 3 166 1.9E-62 T 22-04-2016 L21SP4_RS04310 8723f08c3aad62a1fb65f069dfd240fd 166 Pfam PF02915 Rubrerythrin 5 118 4.1E-22 T 22-04-2016 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 L21SP4_RS04310 8723f08c3aad62a1fb65f069dfd240fd 166 Gene3D G3DSA:2.20.28.10 131 165 7.3E-14 T 22-04-2016 IPR004039 Rubredoxin-type fold L21SP4_RS04310 8723f08c3aad62a1fb65f069dfd240fd 166 Gene3D G3DSA:1.20.1260.10 3 125 3.3E-42 T 22-04-2016 IPR012347 Ferritin-related L21SP4_RS04310 8723f08c3aad62a1fb65f069dfd240fd 166 PANTHER PTHR33746 3 166 1.9E-62 T 22-04-2016 L21SP4_RS04310 8723f08c3aad62a1fb65f069dfd240fd 166 SUPERFAMILY SSF57802 132 164 1.99E-9 T 22-04-2016 L21SP4_RS03945 d794a69320999ee70ad87aca3ea9e5e1 405 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 355 366 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site L21SP4_RS03945 d794a69320999ee70ad87aca3ea9e5e1 405 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 237 248 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site L21SP4_RS03945 d794a69320999ee70ad87aca3ea9e5e1 405 Pfam PF12838 4Fe-4S dicluster domain 236 291 1.5E-7 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain L21SP4_RS03945 d794a69320999ee70ad87aca3ea9e5e1 405 Pfam PF12838 4Fe-4S dicluster domain 323 367 3.6E-8 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain L21SP4_RS03945 d794a69320999ee70ad87aca3ea9e5e1 405 Gene3D G3DSA:3.30.70.20 333 368 4.3E-9 T 22-04-2016 L21SP4_RS03945 d794a69320999ee70ad87aca3ea9e5e1 405 SUPERFAMILY SSF54862 236 374 4.03E-19 T 22-04-2016 L21SP4_RS03945 d794a69320999ee70ad87aca3ea9e5e1 405 Gene3D G3DSA:3.30.70.20 282 332 7.5E-9 T 22-04-2016 L21SP4_RS03945 d794a69320999ee70ad87aca3ea9e5e1 405 PANTHER PTHR30176 95 380 1.2E-17 T 22-04-2016 L21SP4_RS03945 d794a69320999ee70ad87aca3ea9e5e1 405 Pfam PF12801 4Fe-4S binding domain 59 95 4.2E-7 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain L21SP4_RS03945 d794a69320999ee70ad87aca3ea9e5e1 405 Pfam PF12801 4Fe-4S binding domain 143 182 2.4E-4 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain L21SP4_RS03945 d794a69320999ee70ad87aca3ea9e5e1 405 Gene3D G3DSA:3.30.70.20 234 281 6.8E-9 T 22-04-2016 L21SP4_RS05460 b45aa138f3799144be170309afa7ac2b 240 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 99 113 - T 22-04-2016 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 L21SP4_RS05460 b45aa138f3799144be170309afa7ac2b 240 Pfam PF00849 RNA pseudouridylate synthase 62 194 1.7E-18 T 22-04-2016 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 L21SP4_RS05460 b45aa138f3799144be170309afa7ac2b 240 SUPERFAMILY SSF55120 58 230 1.01E-40 T 22-04-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 L21SP4_RS05460 b45aa138f3799144be170309afa7ac2b 240 Pfam PF01479 S4 domain 2 42 3.8E-9 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 L21SP4_RS05460 b45aa138f3799144be170309afa7ac2b 240 PANTHER PTHR21600:SF2 2 232 1.1E-76 T 22-04-2016 L21SP4_RS05460 b45aa138f3799144be170309afa7ac2b 240 Gene3D G3DSA:3.10.290.10 2 64 1.5E-21 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 L21SP4_RS05460 b45aa138f3799144be170309afa7ac2b 240 SMART SM00363 1 60 1.3E-6 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 L21SP4_RS05460 b45aa138f3799144be170309afa7ac2b 240 PANTHER PTHR21600 2 232 1.1E-76 T 22-04-2016 L21SP4_RS05460 b45aa138f3799144be170309afa7ac2b 240 SUPERFAMILY SSF55174 2 67 1.14E-12 T 22-04-2016 L21SP4_RS05460 b45aa138f3799144be170309afa7ac2b 240 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 66 224 1.6E-44 T 22-04-2016 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 L21SP4_RS08650 aa26022fa8cc4b37520c8fa185242da5 328 Gene3D G3DSA:3.40.50.150 230 322 1.6E-49 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS08650 aa26022fa8cc4b37520c8fa185242da5 328 Gene3D G3DSA:3.40.50.150 19 124 1.6E-49 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS08650 aa26022fa8cc4b37520c8fa185242da5 328 PANTHER PTHR11265 18 325 1.5E-127 T 22-04-2016 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 L21SP4_RS08650 aa26022fa8cc4b37520c8fa185242da5 328 Pfam PF01795 MraW methylase family 18 322 6.2E-102 T 22-04-2016 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 L21SP4_RS08650 aa26022fa8cc4b37520c8fa185242da5 328 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 19 323 36.365 T 22-04-2016 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 L21SP4_RS08650 aa26022fa8cc4b37520c8fa185242da5 328 PIRSF PIRSF004486 15 324 3.1E-101 T 22-04-2016 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 L21SP4_RS08650 aa26022fa8cc4b37520c8fa185242da5 328 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 17 322 1.6E-93 T 22-04-2016 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 L21SP4_RS08650 aa26022fa8cc4b37520c8fa185242da5 328 SUPERFAMILY SSF53335 19 127 1.37E-44 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS08650 aa26022fa8cc4b37520c8fa185242da5 328 SUPERFAMILY SSF53335 227 322 1.37E-44 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS08650 aa26022fa8cc4b37520c8fa185242da5 328 Gene3D G3DSA:1.10.150.170 126 229 2.9E-35 T 22-04-2016 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 L21SP4_RS08650 aa26022fa8cc4b37520c8fa185242da5 328 SUPERFAMILY SSF81799 128 227 9.81E-33 T 22-04-2016 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 L21SP4_RS08650 aa26022fa8cc4b37520c8fa185242da5 328 PANTHER PTHR11265:SF0 18 325 1.5E-127 T 22-04-2016 L21SP4_RS03640 78cd6b4209614367ba64121473c3d366 242 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 10 241 1.2E-95 T 22-04-2016 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22|UniPathway: UPA00159 L21SP4_RS03640 78cd6b4209614367ba64121473c3d366 242 Pfam PF00696 Amino acid kinase family 10 220 3.0E-32 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 L21SP4_RS03640 78cd6b4209614367ba64121473c3d366 242 PIRSF PIRSF005650 5 242 1.4E-90 T 22-04-2016 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22|UniPathway: UPA00159 L21SP4_RS03640 78cd6b4209614367ba64121473c3d366 242 Gene3D G3DSA:3.40.1160.10 4 241 1.4E-83 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 L21SP4_RS03640 78cd6b4209614367ba64121473c3d366 242 SUPERFAMILY SSF53633 7 241 1.23E-68 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 L21SP4_RS03640 78cd6b4209614367ba64121473c3d366 242 Hamap MF_01220_B Uridylate kinase [pyrH]. 7 241 43.485 T 22-04-2016 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22|UniPathway: UPA00159 L21SP4_RS03640 78cd6b4209614367ba64121473c3d366 242 PANTHER PTHR21499 6 240 9.4E-109 T 22-04-2016 L21SP4_RS03640 78cd6b4209614367ba64121473c3d366 242 PANTHER PTHR21499:SF23 6 240 9.4E-109 T 22-04-2016 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22|UniPathway: UPA00159 L21SP4_RS07140 6a67ad40cd61d1462d7bf194bd99f084 256 Gene3D G3DSA:3.30.420.40 92 251 1.2E-40 T 22-04-2016 L21SP4_RS07140 6a67ad40cd61d1462d7bf194bd99f084 256 Pfam PF03309 Type III pantothenate kinase 7 202 1.8E-45 T 22-04-2016 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961|UniPathway: UPA00241 L21SP4_RS07140 6a67ad40cd61d1462d7bf194bd99f084 256 Hamap MF_01274 Type III pantothenate kinase [coaX]. 6 250 24.229 T 22-04-2016 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961|UniPathway: UPA00241 L21SP4_RS07140 6a67ad40cd61d1462d7bf194bd99f084 256 SUPERFAMILY SSF53067 121 248 6.04E-28 T 22-04-2016 L21SP4_RS07140 6a67ad40cd61d1462d7bf194bd99f084 256 PANTHER PTHR34265 1 256 7.3E-45 T 22-04-2016 L21SP4_RS07140 6a67ad40cd61d1462d7bf194bd99f084 256 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 7 245 1.9E-47 T 22-04-2016 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961|UniPathway: UPA00241 L21SP4_RS07140 6a67ad40cd61d1462d7bf194bd99f084 256 SUPERFAMILY SSF53067 7 118 7.77E-16 T 22-04-2016 L21SP4_RS12150 24dac4efc61dd8ae55dea49ce8349588 634 Pfam PF09822 ABC-type uncharacterized transport system 37 310 3.0E-60 T 22-04-2016 IPR019196 ABC-type uncharacterised transport system L21SP4_RS09450 ffb65cbc5a06e551a86d381b4440eb9b 1035 Gene3D G3DSA:2.60.120.260 891 979 1.5E-14 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS09450 ffb65cbc5a06e551a86d381b4440eb9b 1035 SUPERFAMILY SSF49785 892 983 2.55E-16 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS09450 ffb65cbc5a06e551a86d381b4440eb9b 1035 SUPERFAMILY SSF55545 41 154 1.26E-7 T 22-04-2016 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like L21SP4_RS09450 ffb65cbc5a06e551a86d381b4440eb9b 1035 Gene3D G3DSA:3.30.379.10 39 152 5.2E-9 T 22-04-2016 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like L21SP4_RS09450 ffb65cbc5a06e551a86d381b4440eb9b 1035 Pfam PF00754 F5/8 type C domain 899 976 2.4E-11 T 22-04-2016 IPR000421 Coagulation factor 5/8 C-terminal domain L21SP4_RS10095 857930fbef6bb5f5483cdb01204fb8a5 823 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 381 516 1.2E-21 T 22-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 L21SP4_RS10095 857930fbef6bb5f5483cdb01204fb8a5 823 SMART SM00382 377 522 5.1E-10 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS10095 857930fbef6bb5f5483cdb01204fb8a5 823 SUPERFAMILY SSF52540 335 587 1.96E-48 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS10095 857930fbef6bb5f5483cdb01204fb8a5 823 Gene3D G3DSA:3.40.50.300 335 529 2.4E-32 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS10095 857930fbef6bb5f5483cdb01204fb8a5 823 PIRSF PIRSF001174 26 804 1.6E-287 T 22-04-2016 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 L21SP4_RS10095 857930fbef6bb5f5483cdb01204fb8a5 823 Hamap MF_01973 Lon protease [lon]. 37 801 64.047 T 22-04-2016 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 L21SP4_RS10095 857930fbef6bb5f5483cdb01204fb8a5 823 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 385 404 8.2E-49 T 22-04-2016 L21SP4_RS10095 857930fbef6bb5f5483cdb01204fb8a5 823 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 732 751 8.2E-49 T 22-04-2016 L21SP4_RS10095 857930fbef6bb5f5483cdb01204fb8a5 823 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 702 721 8.2E-49 T 22-04-2016 L21SP4_RS10095 857930fbef6bb5f5483cdb01204fb8a5 823 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 624 640 8.2E-49 T 22-04-2016 L21SP4_RS10095 857930fbef6bb5f5483cdb01204fb8a5 823 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 755 773 8.2E-49 T 22-04-2016 L21SP4_RS10095 857930fbef6bb5f5483cdb01204fb8a5 823 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 36 231 1.5E-28 T 22-04-2016 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 L21SP4_RS10095 857930fbef6bb5f5483cdb01204fb8a5 823 Gene3D G3DSA:1.10.8.60 530 613 7.6E-26 T 22-04-2016 L21SP4_RS10095 857930fbef6bb5f5483cdb01204fb8a5 823 PANTHER PTHR10046 10 805 0.0 T 22-04-2016 IPR027065 Lon protease GO:0004176|GO:0004252|GO:0005524|GO:0030163 L21SP4_RS10095 857930fbef6bb5f5483cdb01204fb8a5 823 SUPERFAMILY SSF88697 36 230 3.73E-36 T 22-04-2016 IPR015947 PUA-like domain L21SP4_RS10095 857930fbef6bb5f5483cdb01204fb8a5 823 PANTHER PTHR10046:SF24 10 805 0.0 T 22-04-2016 L21SP4_RS10095 857930fbef6bb5f5483cdb01204fb8a5 823 SMART SM00464 36 231 1.6E-34 T 22-04-2016 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 L21SP4_RS10095 857930fbef6bb5f5483cdb01204fb8a5 823 TIGRFAM TIGR00763 lon: endopeptidase La 38 800 2.0E-272 T 22-04-2016 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 L21SP4_RS10095 857930fbef6bb5f5483cdb01204fb8a5 823 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 599 800 7.1E-83 T 22-04-2016 IPR008269 Peptidase S16, Lon C-terminal GO:0004176|GO:0004252|GO:0006508 L21SP4_RS10095 857930fbef6bb5f5483cdb01204fb8a5 823 Gene3D G3DSA:3.30.230.10 622 801 4.8E-67 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup L21SP4_RS10095 857930fbef6bb5f5483cdb01204fb8a5 823 SUPERFAMILY SSF54211 625 800 1.71E-52 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold L21SP4_RS06530 f6c554fb35d4ccffbde80bca42bd4722 280 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 8 28 - T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site L21SP4_RS06530 f6c554fb35d4ccffbde80bca42bd4722 280 SUPERFAMILY SSF54523 10 93 1.57E-14 T 22-04-2016 L21SP4_RS06530 f6c554fb35d4ccffbde80bca42bd4722 280 PRINTS PR00813 Bacterial general secretion pathway protein G signature 45 63 9.2E-7 T 22-04-2016 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 L21SP4_RS06530 f6c554fb35d4ccffbde80bca42bd4722 280 PRINTS PR00813 Bacterial general secretion pathway protein G signature 9 34 9.2E-7 T 22-04-2016 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 L21SP4_RS06530 f6c554fb35d4ccffbde80bca42bd4722 280 Gene3D G3DSA:3.30.700.10 10 64 3.3E-7 T 22-04-2016 L21SP4_RS06530 f6c554fb35d4ccffbde80bca42bd4722 280 PANTHER PTHR30093 8 158 2.8E-17 T 22-04-2016 L21SP4_RS06530 f6c554fb35d4ccffbde80bca42bd4722 280 Pfam PF13544 Type IV pilin N-term methylation site GFxxxE 6 28 2.5E-8 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site L21SP4_RS06530 f6c554fb35d4ccffbde80bca42bd4722 280 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 8 28 1.9E-7 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site L21SP4_RS06530 f6c554fb35d4ccffbde80bca42bd4722 280 TIGRFAM TIGR04294 pre_pil_HX9DG: prepilin-type processing-associated H-X9-DG domain 222 237 3.3E-5 T 22-04-2016 IPR027558 Prepilin-type processing-associated H-X9-DG domain L21SP4_RS01460 cbd5ca23dbada1a1c1209956951c17bd 282 PANTHER PTHR30477 1 277 2.1E-59 T 22-04-2016 L21SP4_RS01460 cbd5ca23dbada1a1c1209956951c17bd 282 SUPERFAMILY SSF81345 14 272 3.92E-29 T 22-04-2016 IPR029022 ABC transporter, BtuC-like L21SP4_RS01460 cbd5ca23dbada1a1c1209956951c17bd 282 Gene3D G3DSA:1.10.3470.10 56 276 5.9E-8 T 22-04-2016 IPR029022 ABC transporter, BtuC-like L21SP4_RS01460 cbd5ca23dbada1a1c1209956951c17bd 282 PANTHER PTHR30477:SF0 1 277 2.1E-59 T 22-04-2016 L21SP4_RS01460 cbd5ca23dbada1a1c1209956951c17bd 282 Pfam PF00950 ABC 3 transport family 14 274 7.0E-63 T 22-04-2016 IPR001626 ABC-3 GO:0005524|GO:0006810|GO:0016020|GO:0042626 L21SP4_RS08755 c2ad914053e3fde11dc395684edbf60c 479 Pfam PF03808 Glycosyl transferase WecB/TagA/CpsF family 62 232 4.1E-58 T 22-04-2016 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|UniPathway: UPA00566 L21SP4_RS08755 c2ad914053e3fde11dc395684edbf60c 479 SUPERFAMILY SSF52091 382 476 4.91E-10 T 22-04-2016 IPR002645 STAS domain L21SP4_RS08755 c2ad914053e3fde11dc395684edbf60c 479 PANTHER PTHR34136:SF1 2 265 1.5E-86 T 22-04-2016 L21SP4_RS08755 c2ad914053e3fde11dc395684edbf60c 479 Gene3D G3DSA:3.30.750.24 383 476 3.6E-10 T 22-04-2016 IPR002645 STAS domain L21SP4_RS08755 c2ad914053e3fde11dc395684edbf60c 479 Gene3D G3DSA:3.30.750.24 289 368 1.0E-10 T 22-04-2016 IPR002645 STAS domain L21SP4_RS08755 c2ad914053e3fde11dc395684edbf60c 479 SUPERFAMILY SSF52091 288 370 6.87E-9 T 22-04-2016 IPR002645 STAS domain L21SP4_RS08755 c2ad914053e3fde11dc395684edbf60c 479 PANTHER PTHR34136 2 265 1.5E-86 T 22-04-2016 L21SP4_RS08755 c2ad914053e3fde11dc395684edbf60c 479 TIGRFAM TIGR00696 wecG_tagA_cpsF: glycosyltransferase, WecB/TagA/CpsF family 58 233 3.9E-41 T 22-04-2016 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|UniPathway: UPA00566 L21SP4_RS08755 c2ad914053e3fde11dc395684edbf60c 479 Pfam PF13466 STAS domain 391 472 3.1E-9 T 22-04-2016 IPR002645 STAS domain L21SP4_RS03490 15f78053170eeaa40d11335bc093c585 327 SUPERFAMILY SSF51569 15 273 1.23E-36 T 22-04-2016 L21SP4_RS03490 15f78053170eeaa40d11335bc093c585 327 Gene3D G3DSA:3.20.20.70 18 271 1.6E-32 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP4_RS03490 15f78053170eeaa40d11335bc093c585 327 Pfam PF00682 HMGL-like 136 261 2.8E-18 T 22-04-2016 IPR000891 Pyruvate carboxyltransferase GO:0003824 L21SP4_RS03490 15f78053170eeaa40d11335bc093c585 327 PANTHER PTHR10277:SF3 19 259 3.3E-22 T 22-04-2016 IPR017629 4-hydroxy-2-oxovalerate aldolase GO:0008701|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 L21SP4_RS03490 15f78053170eeaa40d11335bc093c585 327 PANTHER PTHR10277 19 259 3.3E-22 T 22-04-2016 L21SP4_RS04135 0c52e7dfb0c5bb28433841f706f8c8df 292 PANTHER PTHR31851:SF1 13 291 9.3E-66 T 22-04-2016 L21SP4_RS04135 0c52e7dfb0c5bb28433841f706f8c8df 292 PANTHER PTHR31851 13 291 9.3E-66 T 22-04-2016 L21SP4_RS04135 0c52e7dfb0c5bb28433841f706f8c8df 292 Gene3D G3DSA:1.20.1260.10 18 132 3.1E-13 T 22-04-2016 IPR012347 Ferritin-related L21SP4_RS04135 0c52e7dfb0c5bb28433841f706f8c8df 292 Pfam PF02915 Rubrerythrin 18 129 4.4E-5 T 22-04-2016 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 L21SP4_RS04135 0c52e7dfb0c5bb28433841f706f8c8df 292 Pfam PF01988 VIT family 138 197 2.5E-12 T 22-04-2016 IPR008217 Ccc1 family L21SP4_RS04135 0c52e7dfb0c5bb28433841f706f8c8df 292 SUPERFAMILY SSF47240 6 131 1.62E-16 T 22-04-2016 IPR009078 Ferritin-like superfamily L21SP4_RS02395 e43273e0bd6ecdbf9439f08e2be482e4 608 Pfam PF01807 CHC2 zinc finger 7 100 1.1E-30 T 22-04-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 L21SP4_RS02395 e43273e0bd6ecdbf9439f08e2be482e4 608 Pfam PF13662 Toprim domain 265 339 3.6E-15 T 22-04-2016 IPR006171 Toprim domain L21SP4_RS02395 e43273e0bd6ecdbf9439f08e2be482e4 608 PANTHER PTHR30313 3 439 1.1E-122 T 22-04-2016 L21SP4_RS02395 e43273e0bd6ecdbf9439f08e2be482e4 608 SMART SM00400 36 90 2.9E-27 T 22-04-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 L21SP4_RS02395 e43273e0bd6ecdbf9439f08e2be482e4 608 Gene3D G3DSA:3.40.1360.10 245 367 2.8E-39 T 22-04-2016 L21SP4_RS02395 e43273e0bd6ecdbf9439f08e2be482e4 608 Pfam PF08275 DNA primase catalytic core, N-terminal domain 124 255 1.4E-37 T 22-04-2016 IPR013264 DNA primase, catalytic core, N-terminal L21SP4_RS02395 e43273e0bd6ecdbf9439f08e2be482e4 608 TIGRFAM TIGR01391 dnaG: DNA primase 6 415 9.1E-123 T 22-04-2016 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 L21SP4_RS02395 e43273e0bd6ecdbf9439f08e2be482e4 608 Hamap MF_00974 DNA primase [dnaG]. 3 587 25.419 T 22-04-2016 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 L21SP4_RS02395 e43273e0bd6ecdbf9439f08e2be482e4 608 SMART SM00493 263 334 1.6E-12 T 22-04-2016 IPR006171 Toprim domain L21SP4_RS02395 e43273e0bd6ecdbf9439f08e2be482e4 608 Pfam PF10410 DnaB-helicase binding domain of primase 370 424 4.0E-5 T 22-04-2016 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 L21SP4_RS02395 e43273e0bd6ecdbf9439f08e2be482e4 608 PIRSF PIRSF002811 1 588 1.4E-143 T 22-04-2016 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 L21SP4_RS02395 e43273e0bd6ecdbf9439f08e2be482e4 608 Gene3D G3DSA:3.90.980.10 113 244 1.6E-40 T 22-04-2016 IPR013264 DNA primase, catalytic core, N-terminal L21SP4_RS02395 e43273e0bd6ecdbf9439f08e2be482e4 608 SUPERFAMILY SSF57783 6 101 4.93E-30 T 22-04-2016 L21SP4_RS02395 e43273e0bd6ecdbf9439f08e2be482e4 608 SUPERFAMILY SSF56731 113 425 4.18E-89 T 22-04-2016 L21SP4_RS02395 e43273e0bd6ecdbf9439f08e2be482e4 608 Gene3D G3DSA:3.90.580.10 6 101 3.7E-33 T 22-04-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 L21SP4_RS09655 385168e0ebb74eb5e129c5fc316f6b2a 412 Pfam PF13542 Helix-turn-helix domain of transposase family ISL3 94 140 1.8E-9 T 22-04-2016 IPR032877 Transposase IS204/IS1001/IS1096/IS1165, helix-turn-helix domain L21SP4_RS09655 385168e0ebb74eb5e129c5fc316f6b2a 412 Pfam PF01610 Transposase 157 394 9.6E-78 T 22-04-2016 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain L21SP4_RS09655 385168e0ebb74eb5e129c5fc316f6b2a 412 PANTHER PTHR33498:SF1 1 384 2.4E-51 T 22-04-2016 L21SP4_RS09655 385168e0ebb74eb5e129c5fc316f6b2a 412 PANTHER PTHR33498 1 384 2.4E-51 T 22-04-2016 L21SP4_RS03340 385168e0ebb74eb5e129c5fc316f6b2a 412 Pfam PF13542 Helix-turn-helix domain of transposase family ISL3 94 140 1.8E-9 T 22-04-2016 IPR032877 Transposase IS204/IS1001/IS1096/IS1165, helix-turn-helix domain L21SP4_RS03340 385168e0ebb74eb5e129c5fc316f6b2a 412 Pfam PF01610 Transposase 157 394 9.6E-78 T 22-04-2016 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain L21SP4_RS03340 385168e0ebb74eb5e129c5fc316f6b2a 412 PANTHER PTHR33498:SF1 1 384 2.4E-51 T 22-04-2016 L21SP4_RS03340 385168e0ebb74eb5e129c5fc316f6b2a 412 PANTHER PTHR33498 1 384 2.4E-51 T 22-04-2016 L21SP4_RS03375 385168e0ebb74eb5e129c5fc316f6b2a 412 Pfam PF13542 Helix-turn-helix domain of transposase family ISL3 94 140 1.8E-9 T 22-04-2016 IPR032877 Transposase IS204/IS1001/IS1096/IS1165, helix-turn-helix domain L21SP4_RS03375 385168e0ebb74eb5e129c5fc316f6b2a 412 Pfam PF01610 Transposase 157 394 9.6E-78 T 22-04-2016 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain L21SP4_RS03375 385168e0ebb74eb5e129c5fc316f6b2a 412 PANTHER PTHR33498:SF1 1 384 2.4E-51 T 22-04-2016 L21SP4_RS03375 385168e0ebb74eb5e129c5fc316f6b2a 412 PANTHER PTHR33498 1 384 2.4E-51 T 22-04-2016 L21SP4_RS04965 81ac567503faeaab2a9f95b1cce9550f 333 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 141 162 8.9E-24 T 22-04-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 L21SP4_RS04965 81ac567503faeaab2a9f95b1cce9550f 333 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 66 85 8.9E-24 T 22-04-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 L21SP4_RS04965 81ac567503faeaab2a9f95b1cce9550f 333 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 16 32 8.9E-24 T 22-04-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 L21SP4_RS04965 81ac567503faeaab2a9f95b1cce9550f 333 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 192 202 8.9E-24 T 22-04-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 L21SP4_RS04965 81ac567503faeaab2a9f95b1cce9550f 333 Pfam PF00579 tRNA synthetases class I (W and Y) 5 277 3.4E-60 T 22-04-2016 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 L21SP4_RS04965 81ac567503faeaab2a9f95b1cce9550f 333 Gene3D G3DSA:3.40.50.620 3 201 5.5E-79 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP4_RS04965 81ac567503faeaab2a9f95b1cce9550f 333 SUPERFAMILY SSF52374 5 322 8.59E-89 T 22-04-2016 L21SP4_RS04965 81ac567503faeaab2a9f95b1cce9550f 333 PANTHER PTHR10055:SF10 5 326 9.1E-128 T 22-04-2016 L21SP4_RS04965 81ac567503faeaab2a9f95b1cce9550f 333 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 4 322 1.6E-93 T 22-04-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 L21SP4_RS04965 81ac567503faeaab2a9f95b1cce9550f 333 Gene3D G3DSA:1.10.240.10 202 290 4.3E-31 T 22-04-2016 L21SP4_RS04965 81ac567503faeaab2a9f95b1cce9550f 333 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 3 323 37.497 T 22-04-2016 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2 L21SP4_RS04965 81ac567503faeaab2a9f95b1cce9550f 333 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 12 21 - T 22-04-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 L21SP4_RS04965 81ac567503faeaab2a9f95b1cce9550f 333 PANTHER PTHR10055 5 326 9.1E-128 T 22-04-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 L21SP4_RS04785 2114f23f67076231f88db7d9cd9e3b06 578 SUPERFAMILY SSF47384 341 412 1.12E-15 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS04785 2114f23f67076231f88db7d9cd9e3b06 578 Pfam PF00989 PAS fold 219 328 2.6E-17 T 22-04-2016 IPR013767 PAS fold GO:0006355 L21SP4_RS04785 2114f23f67076231f88db7d9cd9e3b06 578 SUPERFAMILY SSF55785 99 212 6.46E-21 T 22-04-2016 IPR000014 PAS domain L21SP4_RS04785 2114f23f67076231f88db7d9cd9e3b06 578 Gene3D G3DSA:3.30.565.10 418 572 1.2E-38 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS04785 2114f23f67076231f88db7d9cd9e3b06 578 SMART SM00086 166 209 3.6E-8 T 22-04-2016 IPR001610 PAC motif L21SP4_RS04785 2114f23f67076231f88db7d9cd9e3b06 578 SMART SM00086 289 331 2.6E-8 T 22-04-2016 IPR001610 PAC motif L21SP4_RS04785 2114f23f67076231f88db7d9cd9e3b06 578 Pfam PF00512 His Kinase A (phospho-acceptor) domain 348 411 5.3E-15 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS04785 2114f23f67076231f88db7d9cd9e3b06 578 Gene3D G3DSA:3.30.450.20 226 330 6.4E-29 T 22-04-2016 L21SP4_RS04785 2114f23f67076231f88db7d9cd9e3b06 578 SMART SM00091 91 159 3.3E-4 T 22-04-2016 IPR000014 PAS domain L21SP4_RS04785 2114f23f67076231f88db7d9cd9e3b06 578 SMART SM00091 217 283 2.0E-10 T 22-04-2016 IPR000014 PAS domain L21SP4_RS04785 2114f23f67076231f88db7d9cd9e3b06 578 PRINTS PR00344 Bacterial sensor protein C-terminal signature 503 517 3.0E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS04785 2114f23f67076231f88db7d9cd9e3b06 578 PRINTS PR00344 Bacterial sensor protein C-terminal signature 534 552 3.0E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS04785 2114f23f67076231f88db7d9cd9e3b06 578 PRINTS PR00344 Bacterial sensor protein C-terminal signature 558 571 3.0E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS04785 2114f23f67076231f88db7d9cd9e3b06 578 PRINTS PR00344 Bacterial sensor protein C-terminal signature 521 531 3.0E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS04785 2114f23f67076231f88db7d9cd9e3b06 578 Pfam PF08447 PAS fold 114 203 1.2E-24 T 22-04-2016 IPR013655 PAS fold-3 GO:0005515 L21SP4_RS04785 2114f23f67076231f88db7d9cd9e3b06 578 Gene3D G3DSA:3.30.450.20 79 225 1.1E-36 T 22-04-2016 L21SP4_RS04785 2114f23f67076231f88db7d9cd9e3b06 578 Gene3D G3DSA:1.10.287.130 342 410 1.0E-12 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS04785 2114f23f67076231f88db7d9cd9e3b06 578 SUPERFAMILY SSF55785 223 329 3.87E-30 T 22-04-2016 IPR000014 PAS domain L21SP4_RS04785 2114f23f67076231f88db7d9cd9e3b06 578 PANTHER PTHR24423 73 573 1.2E-111 T 22-04-2016 L21SP4_RS04785 2114f23f67076231f88db7d9cd9e3b06 578 SMART SM00387 456 574 7.8E-27 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS04785 2114f23f67076231f88db7d9cd9e3b06 578 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 217 338 2.9E-24 T 22-04-2016 IPR000014 PAS domain L21SP4_RS04785 2114f23f67076231f88db7d9cd9e3b06 578 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 88 214 8.5E-8 T 22-04-2016 IPR000014 PAS domain L21SP4_RS04785 2114f23f67076231f88db7d9cd9e3b06 578 SMART SM00388 346 414 4.8E-16 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS04785 2114f23f67076231f88db7d9cd9e3b06 578 SUPERFAMILY SSF55874 404 572 3.55E-35 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS04785 2114f23f67076231f88db7d9cd9e3b06 578 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 458 572 2.5E-17 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS08640 d5c06f5935a6e87b945d304a154cd3db 567 SUPERFAMILY SSF56519 43 209 1.57E-39 T 22-04-2016 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 L21SP4_RS08640 d5c06f5935a6e87b945d304a154cd3db 567 PANTHER PTHR30627:SF1 5 560 3.9E-169 T 22-04-2016 L21SP4_RS08640 d5c06f5935a6e87b945d304a154cd3db 567 Pfam PF00905 Penicillin binding protein transpeptidase domain 237 543 1.1E-73 T 22-04-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 L21SP4_RS08640 d5c06f5935a6e87b945d304a154cd3db 567 Gene3D G3DSA:3.40.710.10 217 548 1.3E-90 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like L21SP4_RS08640 d5c06f5935a6e87b945d304a154cd3db 567 Gene3D G3DSA:3.90.1310.10 116 216 1.9E-29 T 22-04-2016 L21SP4_RS08640 d5c06f5935a6e87b945d304a154cd3db 567 PANTHER PTHR30627 5 560 3.9E-169 T 22-04-2016 L21SP4_RS08640 d5c06f5935a6e87b945d304a154cd3db 567 SUPERFAMILY SSF56601 161 557 3.42E-95 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like L21SP4_RS08640 d5c06f5935a6e87b945d304a154cd3db 567 Pfam PF03717 Penicillin-binding Protein dimerisation domain 44 191 1.2E-12 T 22-04-2016 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 L21SP4_RS10350 4edb1c8a99fcbd6dfde2bbc95d7196a9 236 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 L21SP4_RS10350 4edb1c8a99fcbd6dfde2bbc95d7196a9 236 Pfam PF00005 ABC transporter 35 184 1.0E-32 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 L21SP4_RS10350 4edb1c8a99fcbd6dfde2bbc95d7196a9 236 SMART SM00382 44 234 1.2E-11 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS10350 4edb1c8a99fcbd6dfde2bbc95d7196a9 236 Gene3D G3DSA:3.40.50.300 15 234 3.2E-66 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS10350 4edb1c8a99fcbd6dfde2bbc95d7196a9 236 PANTHER PTHR24220 17 235 8.6E-93 T 22-04-2016 L21SP4_RS10350 4edb1c8a99fcbd6dfde2bbc95d7196a9 236 PANTHER PTHR24220:SF111 17 235 8.6E-93 T 22-04-2016 L21SP4_RS10350 4edb1c8a99fcbd6dfde2bbc95d7196a9 236 SUPERFAMILY SSF52540 15 234 3.64E-67 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS09075 0b38d7a7dd3f7c1accff6d118d6e5617 560 Gene3D G3DSA:3.40.640.10 183 429 2.1E-105 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 L21SP4_RS09075 0b38d7a7dd3f7c1accff6d118d6e5617 560 SUPERFAMILY SSF89623 1 145 2.35E-51 T 22-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 L21SP4_RS09075 0b38d7a7dd3f7c1accff6d118d6e5617 560 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 368 384 - T 22-04-2016 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0004372|GO:0006544|GO:0006563|GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 L21SP4_RS09075 0b38d7a7dd3f7c1accff6d118d6e5617 560 Pfam PF02502 Ribose/Galactose Isomerase 3 141 4.9E-52 T 22-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 L21SP4_RS09075 0b38d7a7dd3f7c1accff6d118d6e5617 560 SUPERFAMILY SSF53383 153 560 2.95E-174 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase L21SP4_RS09075 0b38d7a7dd3f7c1accff6d118d6e5617 560 PANTHER PTHR11680 119 560 6.9E-241 T 22-04-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 L21SP4_RS09075 0b38d7a7dd3f7c1accff6d118d6e5617 560 Pfam PF00464 Serine hydroxymethyltransferase 155 530 6.0E-169 T 22-04-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 L21SP4_RS09075 0b38d7a7dd3f7c1accff6d118d6e5617 560 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 3 146 1.1E-53 T 22-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 L21SP4_RS09075 0b38d7a7dd3f7c1accff6d118d6e5617 560 Gene3D G3DSA:3.40.1400.10 1 147 3.4E-58 T 22-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 L21SP4_RS09075 0b38d7a7dd3f7c1accff6d118d6e5617 560 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 153 560 51.843 T 22-04-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 L21SP4_RS09075 0b38d7a7dd3f7c1accff6d118d6e5617 560 TIGRFAM TIGR01120 rpiB: ribose 5-phosphate isomerase B 2 144 7.0E-52 T 22-04-2016 IPR004785 Ribose 5-phosphate isomerase B GO:0004751|GO:0006098 L21SP4_RS09075 0b38d7a7dd3f7c1accff6d118d6e5617 560 Gene3D G3DSA:3.90.1150.10 430 560 2.4E-56 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 L21SP4_RS04315 8c87e267449b0049c843ee967f21dcf2 1813 Gene3D G3DSA:3.30.300.30 840 932 2.3E-23 T 22-04-2016 L21SP4_RS04315 8c87e267449b0049c843ee967f21dcf2 1813 Pfam PF00550 Phosphopantetheine attachment site 1487 1550 8.5E-13 T 22-04-2016 IPR009081 Phosphopantetheine binding ACP domain L21SP4_RS04315 8c87e267449b0049c843ee967f21dcf2 1813 Gene3D G3DSA:3.40.50.980 977 1133 1.1E-42 T 22-04-2016 L21SP4_RS04315 8c87e267449b0049c843ee967f21dcf2 1813 PANTHER PTHR24095:SF137 9 1459 6.6E-243 T 22-04-2016 L21SP4_RS04315 8c87e267449b0049c843ee967f21dcf2 1813 SUPERFAMILY SSF52777 181 417 1.67E-35 T 22-04-2016 L21SP4_RS04315 8c87e267449b0049c843ee967f21dcf2 1813 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1509 1524 - T 22-04-2016 IPR006162 Phosphopantetheine attachment site L21SP4_RS04315 8c87e267449b0049c843ee967f21dcf2 1813 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1003 1399 4.5E-119 T 22-04-2016 IPR010071 Amino acid adenylation domain L21SP4_RS04315 8c87e267449b0049c843ee967f21dcf2 1813 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 476 870 4.1E-132 T 22-04-2016 IPR010071 Amino acid adenylation domain L21SP4_RS04315 8c87e267449b0049c843ee967f21dcf2 1813 Pfam PF13193 AMP-binding enzyme C-terminal domain 1383 1459 1.9E-8 T 22-04-2016 IPR025110 AMP-binding enzyme C-terminal domain L21SP4_RS04315 8c87e267449b0049c843ee967f21dcf2 1813 SMART SM00824 Thioesterase 1577 1813 5.5E-5 T 22-04-2016 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 L21SP4_RS04315 8c87e267449b0049c843ee967f21dcf2 1813 Gene3D G3DSA:3.40.50.980 1134 1286 2.0E-33 T 22-04-2016 L21SP4_RS04315 8c87e267449b0049c843ee967f21dcf2 1813 Gene3D G3DSA:3.30.300.30 1370 1489 9.6E-34 T 22-04-2016 L21SP4_RS04315 8c87e267449b0049c843ee967f21dcf2 1813 Pfam PF00975 Thioesterase domain 1575 1811 2.0E-26 T 22-04-2016 IPR001031 Thioesterase GO:0009058|GO:0016788 L21SP4_RS04315 8c87e267449b0049c843ee967f21dcf2 1813 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1123 1134 - T 22-04-2016 IPR020845 AMP-binding, conserved site L21SP4_RS04315 8c87e267449b0049c843ee967f21dcf2 1813 ProSitePatterns PS00455 Putative AMP-binding domain signature. 597 608 - T 22-04-2016 IPR020845 AMP-binding, conserved site L21SP4_RS04315 8c87e267449b0049c843ee967f21dcf2 1813 Gene3D G3DSA:2.30.38.10 1287 1365 1.3E-25 T 22-04-2016 L21SP4_RS04315 8c87e267449b0049c843ee967f21dcf2 1813 Gene3D G3DSA:2.30.38.10 758 835 4.5E-29 T 22-04-2016 L21SP4_RS04315 8c87e267449b0049c843ee967f21dcf2 1813 Pfam PF00501 AMP-binding enzyme 987 1375 1.4E-88 T 22-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 L21SP4_RS04315 8c87e267449b0049c843ee967f21dcf2 1813 Pfam PF00501 AMP-binding enzyme 456 846 2.7E-96 T 22-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 L21SP4_RS04315 8c87e267449b0049c843ee967f21dcf2 1813 SUPERFAMILY SSF56801 415 936 1.96E-149 T 22-04-2016 L21SP4_RS04315 8c87e267449b0049c843ee967f21dcf2 1813 Gene3D G3DSA:1.10.1200.10 1490 1553 8.6E-25 T 22-04-2016 IPR009081 Phosphopantetheine binding ACP domain L21SP4_RS04315 8c87e267449b0049c843ee967f21dcf2 1813 SUPERFAMILY SSF52777 10 177 1.33E-37 T 22-04-2016 L21SP4_RS04315 8c87e267449b0049c843ee967f21dcf2 1813 Gene3D G3DSA:3.40.50.980 617 757 6.4E-36 T 22-04-2016 L21SP4_RS04315 8c87e267449b0049c843ee967f21dcf2 1813 SUPERFAMILY SSF53474 1557 1813 8.25E-54 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold L21SP4_RS04315 8c87e267449b0049c843ee967f21dcf2 1813 Pfam PF00668 Condensation domain 9 295 5.6E-44 T 22-04-2016 IPR001242 Condensation domain L21SP4_RS04315 8c87e267449b0049c843ee967f21dcf2 1813 PANTHER PTHR24095 9 1459 6.6E-243 T 22-04-2016 L21SP4_RS04315 8c87e267449b0049c843ee967f21dcf2 1813 SUPERFAMILY SSF47336 1479 1551 1.44E-18 T 22-04-2016 IPR009081 Phosphopantetheine binding ACP domain L21SP4_RS04315 8c87e267449b0049c843ee967f21dcf2 1813 SUPERFAMILY SSF56801 955 1498 1.09E-139 T 22-04-2016 L21SP4_RS04315 8c87e267449b0049c843ee967f21dcf2 1813 Gene3D G3DSA:3.40.50.980 449 614 2.3E-49 T 22-04-2016 L21SP4_RS04315 8c87e267449b0049c843ee967f21dcf2 1813 SMART SM00823 Phosphopantetheine attachment site 1485 1554 1.8E-6 T 22-04-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 L21SP4_RS04315 8c87e267449b0049c843ee967f21dcf2 1813 Gene3D G3DSA:3.40.50.1820 1563 1677 9.9E-44 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold L21SP4_RS04315 8c87e267449b0049c843ee967f21dcf2 1813 Gene3D G3DSA:3.40.50.1820 1746 1813 9.9E-44 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold L21SP4_RS00225 335671b350f3253140f67e14d88cb697 118 Gene3D G3DSA:1.10.260.40 6 96 1.2E-14 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 L21SP4_RS00225 335671b350f3253140f67e14d88cb697 118 Pfam PF13560 Helix-turn-helix domain 6 59 6.1E-12 T 22-04-2016 L21SP4_RS00225 335671b350f3253140f67e14d88cb697 118 SUPERFAMILY SSF47413 5 61 4.17E-13 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 L21SP4_RS00225 335671b350f3253140f67e14d88cb697 118 SMART SM00530 6 61 2.5E-11 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 L21SP4_RS05455 88b8074014d1b4e772831c8bf40749be 967 SUPERFAMILY SSF63411 514 761 2.12E-55 T 22-04-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 L21SP4_RS05455 88b8074014d1b4e772831c8bf40749be 967 PANTHER PTHR11851:SF150 394 963 1.6E-242 T 22-04-2016 L21SP4_RS05455 88b8074014d1b4e772831c8bf40749be 967 PANTHER PTHR11851:SF150 6 378 1.6E-242 T 22-04-2016 L21SP4_RS05455 88b8074014d1b4e772831c8bf40749be 967 SUPERFAMILY SSF63411 15 246 5.68E-44 T 22-04-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 L21SP4_RS05455 88b8074014d1b4e772831c8bf40749be 967 Pfam PF05193 Peptidase M16 inactive domain 199 379 5.0E-18 T 22-04-2016 IPR007863 Peptidase M16, C-terminal L21SP4_RS05455 88b8074014d1b4e772831c8bf40749be 967 PANTHER PTHR11851 394 963 1.6E-242 T 22-04-2016 L21SP4_RS05455 88b8074014d1b4e772831c8bf40749be 967 PANTHER PTHR11851 6 378 1.6E-242 T 22-04-2016 L21SP4_RS05455 88b8074014d1b4e772831c8bf40749be 967 SUPERFAMILY SSF63411 253 511 5.8E-50 T 22-04-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 L21SP4_RS05455 88b8074014d1b4e772831c8bf40749be 967 Pfam PF08367 Peptidase M16C associated 454 703 9.8E-60 T 22-04-2016 IPR013578 Peptidase M16C associated GO:0006508 L21SP4_RS05455 88b8074014d1b4e772831c8bf40749be 967 Gene3D G3DSA:3.30.830.10 28 250 1.8E-40 T 22-04-2016 IPR011237 Peptidase M16 domain GO:0046872 L21SP4_RS05455 88b8074014d1b4e772831c8bf40749be 967 SUPERFAMILY SSF63411 778 953 1.25E-26 T 22-04-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 L21SP4_RS05455 88b8074014d1b4e772831c8bf40749be 967 SMART SM01264 454 703 4.7E-80 T 22-04-2016 IPR013578 Peptidase M16C associated GO:0006508 L21SP4_RS08095 4b82a4b38ab40af5b5ef5a9d1d803d4f 369 Pfam PF01546 Peptidase family M20/M25/M40 69 362 4.0E-21 T 22-04-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 L21SP4_RS08095 4b82a4b38ab40af5b5ef5a9d1d803d4f 369 Pfam PF07687 Peptidase dimerisation domain 166 263 1.0E-6 T 22-04-2016 IPR011650 Peptidase M20, dimerisation domain L21SP4_RS08095 4b82a4b38ab40af5b5ef5a9d1d803d4f 369 Gene3D G3DSA:3.40.630.10 7 177 1.6E-43 T 22-04-2016 L21SP4_RS08095 4b82a4b38ab40af5b5ef5a9d1d803d4f 369 Gene3D G3DSA:3.40.630.10 306 365 1.6E-43 T 22-04-2016 L21SP4_RS08095 4b82a4b38ab40af5b5ef5a9d1d803d4f 369 SUPERFAMILY SSF55031 169 275 2.44E-9 T 22-04-2016 IPR011650 Peptidase M20, dimerisation domain L21SP4_RS08095 4b82a4b38ab40af5b5ef5a9d1d803d4f 369 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 68 77 - T 22-04-2016 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 L21SP4_RS08095 4b82a4b38ab40af5b5ef5a9d1d803d4f 369 PANTHER PTHR11014 6 369 8.0E-40 T 22-04-2016 L21SP4_RS08095 4b82a4b38ab40af5b5ef5a9d1d803d4f 369 Gene3D G3DSA:3.30.70.360 178 267 3.1E-10 T 22-04-2016 IPR011650 Peptidase M20, dimerisation domain L21SP4_RS08095 4b82a4b38ab40af5b5ef5a9d1d803d4f 369 SUPERFAMILY SSF53187 290 365 4.37E-41 T 22-04-2016 L21SP4_RS08095 4b82a4b38ab40af5b5ef5a9d1d803d4f 369 SUPERFAMILY SSF53187 6 177 4.37E-41 T 22-04-2016 L21SP4_RS04915 c5d4597fd6d6314f11ed631b9c669d09 611 SUPERFAMILY SSF56601 254 601 5.27E-95 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like L21SP4_RS04915 c5d4597fd6d6314f11ed631b9c669d09 611 Gene3D G3DSA:3.90.1310.10 159 260 3.1E-16 T 22-04-2016 L21SP4_RS04915 c5d4597fd6d6314f11ed631b9c669d09 611 PANTHER PTHR30627:SF2 1 601 4.7E-154 T 22-04-2016 L21SP4_RS04915 c5d4597fd6d6314f11ed631b9c669d09 611 PANTHER PTHR30627 1 601 4.7E-154 T 22-04-2016 L21SP4_RS04915 c5d4597fd6d6314f11ed631b9c669d09 611 Pfam PF00905 Penicillin binding protein transpeptidase domain 271 596 7.3E-66 T 22-04-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 L21SP4_RS04915 c5d4597fd6d6314f11ed631b9c669d09 611 SUPERFAMILY SSF56519 52 252 7.59E-31 T 22-04-2016 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 L21SP4_RS04915 c5d4597fd6d6314f11ed631b9c669d09 611 Gene3D G3DSA:3.40.710.10 261 601 6.1E-102 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like L21SP4_RS04915 c5d4597fd6d6314f11ed631b9c669d09 611 Pfam PF03717 Penicillin-binding Protein dimerisation domain 60 234 5.7E-21 T 22-04-2016 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 L21SP4_RS04915 c5d4597fd6d6314f11ed631b9c669d09 611 TIGRFAM TIGR03423 pbp2_mrdA: penicillin-binding protein 2 15 600 1.7E-162 T 22-04-2016 IPR017790 Penicillin-binding protein 2 GO:0016020 UniPathway: UPA00219 L21SP4_RS11920 60ac76f3a81f42344259f9592384656f 278 PANTHER PTHR11904 1 272 9.5E-82 T 22-04-2016 IPR001369 PNP/MTAP phosphorylase L21SP4_RS11920 60ac76f3a81f42344259f9592384656f 278 SUPERFAMILY SSF53167 5 270 3.89E-70 T 22-04-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 L21SP4_RS11920 60ac76f3a81f42344259f9592384656f 278 PANTHER PTHR11904:SF9 1 272 9.5E-82 T 22-04-2016 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|UniPathway: UPA00606 L21SP4_RS11920 60ac76f3a81f42344259f9592384656f 278 Gene3D G3DSA:3.40.50.1580 5 270 6.4E-74 T 22-04-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 L21SP4_RS11920 60ac76f3a81f42344259f9592384656f 278 TIGRFAM TIGR01697 PNPH-PUNA-XAPA: inosine/guanosine/xanthosine phosphorylase family 26 269 1.0E-72 T 22-04-2016 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|UniPathway: UPA00606 L21SP4_RS11920 60ac76f3a81f42344259f9592384656f 278 PIRSF PIRSF000477 3 272 5.3E-75 T 22-04-2016 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|UniPathway: UPA00606 L21SP4_RS11920 60ac76f3a81f42344259f9592384656f 278 Pfam PF01048 Phosphorylase superfamily 26 270 6.0E-43 T 22-04-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 L21SP4_RS00605 1ad461a20d6a78c9c372ff6300c1100e 434 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 156 169 - T 22-04-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 L21SP4_RS00605 1ad461a20d6a78c9c372ff6300c1100e 434 Gene3D G3DSA:1.10.8.60 305 376 2.6E-26 T 22-04-2016 L21SP4_RS00605 1ad461a20d6a78c9c372ff6300c1100e 434 SMART SM00382 152 296 5.7E-12 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS00605 1ad461a20d6a78c9c372ff6300c1100e 434 SUPERFAMILY SSF52540 131 375 7.57E-69 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS00605 1ad461a20d6a78c9c372ff6300c1100e 434 Gene3D G3DSA:3.40.50.300 128 304 1.5E-54 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS00605 1ad461a20d6a78c9c372ff6300c1100e 434 Pfam PF02954 Bacterial regulatory protein, Fis family 392 431 5.4E-13 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 L21SP4_RS00605 1ad461a20d6a78c9c372ff6300c1100e 434 Pfam PF13426 PAS domain 13 114 2.4E-14 T 22-04-2016 IPR000014 PAS domain L21SP4_RS00605 1ad461a20d6a78c9c372ff6300c1100e 434 Pfam PF00158 Sigma-54 interaction domain 133 298 1.5E-65 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 L21SP4_RS00605 1ad461a20d6a78c9c372ff6300c1100e 434 SUPERFAMILY SSF55785 3 111 2.44E-19 T 22-04-2016 IPR000014 PAS domain L21SP4_RS00605 1ad461a20d6a78c9c372ff6300c1100e 434 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 414 434 2.4E-10 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 L21SP4_RS00605 1ad461a20d6a78c9c372ff6300c1100e 434 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 397 414 2.4E-10 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 L21SP4_RS00605 1ad461a20d6a78c9c372ff6300c1100e 434 PANTHER PTHR32071 116 434 1.7E-150 T 22-04-2016 L21SP4_RS00605 1ad461a20d6a78c9c372ff6300c1100e 434 Gene3D G3DSA:3.30.450.20 3 114 4.0E-21 T 22-04-2016 L21SP4_RS00605 1ad461a20d6a78c9c372ff6300c1100e 434 SUPERFAMILY SSF46689 346 434 2.11E-15 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS00605 1ad461a20d6a78c9c372ff6300c1100e 434 SMART SM00091 2 68 8.5E-7 T 22-04-2016 IPR000014 PAS domain L21SP4_RS00605 1ad461a20d6a78c9c372ff6300c1100e 434 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 345 354 - T 22-04-2016 IPR025944 Sigma-54 interaction domain, conserved site L21SP4_RS00605 1ad461a20d6a78c9c372ff6300c1100e 434 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 2 121 1.9E-13 T 22-04-2016 IPR000014 PAS domain L21SP4_RS00605 1ad461a20d6a78c9c372ff6300c1100e 434 Gene3D G3DSA:1.10.10.60 377 434 3.3E-16 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS02735 42379783cb6b6ed2d12e78af483af7a3 393 Hamap MF_01825 Erythronate-4-phosphate dehydrogenase [pdxB]. 4 373 37.076 T 22-04-2016 IPR020921 Erythronate-4-phosphate dehydrogenase GO:0005737|GO:0008615|GO:0033711|GO:0055114 KEGG: 00260+1.1.1.29|KEGG: 00630+1.1.1.29|KEGG: 00680+1.1.1.29|KEGG: 00750+1.1.1.290|MetaCyc: PWY-181|UniPathway: UPA00244 L21SP4_RS02735 42379783cb6b6ed2d12e78af483af7a3 393 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 105 265 5.6E-33 T 22-04-2016 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 L21SP4_RS02735 42379783cb6b6ed2d12e78af483af7a3 393 PANTHER PTHR10996:SF111 10 341 1.4E-98 T 22-04-2016 L21SP4_RS02735 42379783cb6b6ed2d12e78af483af7a3 393 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 31 285 3.3E-15 T 22-04-2016 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 L21SP4_RS02735 42379783cb6b6ed2d12e78af483af7a3 393 Gene3D G3DSA:3.40.50.720 10 95 4.1E-19 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS02735 42379783cb6b6ed2d12e78af483af7a3 393 SUPERFAMILY SSF52283 10 107 2.0E-16 T 22-04-2016 L21SP4_RS02735 42379783cb6b6ed2d12e78af483af7a3 393 PANTHER PTHR10996 10 341 1.4E-98 T 22-04-2016 L21SP4_RS02735 42379783cb6b6ed2d12e78af483af7a3 393 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 206 222 - T 22-04-2016 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site L21SP4_RS02735 42379783cb6b6ed2d12e78af483af7a3 393 Gene3D G3DSA:3.40.50.720 96 267 3.7E-39 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS02735 42379783cb6b6ed2d12e78af483af7a3 393 SUPERFAMILY SSF51735 88 266 9.87E-35 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS02735 42379783cb6b6ed2d12e78af483af7a3 393 Pfam PF11890 Domain of unknown function (DUF3410) 299 373 1.1E-13 T 22-04-2016 IPR024531 Erythronate-4-phosphate dehydrogenase, dimerisation domain GO:0046983 KEGG: 00260+1.1.1.29|KEGG: 00630+1.1.1.29|KEGG: 00680+1.1.1.29|KEGG: 00750+1.1.1.290|MetaCyc: PWY-181|UniPathway: UPA00244 L21SP4_RS10970 5e33d49ef8902f6e52141d4ad2a9aac5 474 Pfam PF01618 MotA/TolQ/ExbB proton channel family 329 448 5.0E-30 T 22-04-2016 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 L21SP4_RS10970 5e33d49ef8902f6e52141d4ad2a9aac5 474 PANTHER PTHR30625 233 471 2.2E-42 T 22-04-2016 L21SP4_RS10970 5e33d49ef8902f6e52141d4ad2a9aac5 474 PANTHER PTHR30625:SF0 233 471 2.2E-42 T 22-04-2016 L21SP4_RS10970 5e33d49ef8902f6e52141d4ad2a9aac5 474 PIRSF PIRSF037714 2 473 1.6E-98 T 22-04-2016 IPR017270 Putative MotA/TolQ/ExbB family protein L21SP4_RS12045 216b5768ba8639cd7226daebb5028b27 191 PANTHER PTHR34047 38 136 5.6E-21 T 22-04-2016 L21SP4_RS12045 216b5768ba8639cd7226daebb5028b27 191 SUPERFAMILY SSF56672 56 158 2.67E-6 T 22-04-2016 L21SP4_RS08365 4374dba9c46032613ad751f6e6734fe8 67 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 60 15.915 T 22-04-2016 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS08365 4374dba9c46032613ad751f6e6734fe8 67 Gene3D G3DSA:1.10.287.310 1 61 6.6E-23 T 22-04-2016 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS08365 4374dba9c46032613ad751f6e6734fe8 67 SUPERFAMILY SSF46561 1 62 2.75E-19 T 22-04-2016 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS08365 4374dba9c46032613ad751f6e6734fe8 67 Pfam PF00831 Ribosomal L29 protein 4 59 5.3E-21 T 22-04-2016 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS08365 4374dba9c46032613ad751f6e6734fe8 67 PANTHER PTHR10916 1 64 2.8E-20 T 22-04-2016 L21SP4_RS08365 4374dba9c46032613ad751f6e6734fe8 67 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 59 4.9E-19 T 22-04-2016 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS01615 b06e254d17d861ce45c64b03e4078c3e 410 PANTHER PTHR11019:SF105 311 409 1.0E-26 T 22-04-2016 L21SP4_RS01615 b06e254d17d861ce45c64b03e4078c3e 410 Gene3D G3DSA:1.10.10.60 301 354 1.5E-10 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS01615 b06e254d17d861ce45c64b03e4078c3e 410 Pfam PF12833 Helix-turn-helix domain 325 402 9.5E-23 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP4_RS01615 b06e254d17d861ce45c64b03e4078c3e 410 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 385 401 5.7E-6 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 L21SP4_RS01615 b06e254d17d861ce45c64b03e4078c3e 410 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 370 385 5.7E-6 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 L21SP4_RS01615 b06e254d17d861ce45c64b03e4078c3e 410 Gene3D G3DSA:1.10.10.60 355 405 3.0E-19 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS01615 b06e254d17d861ce45c64b03e4078c3e 410 PANTHER PTHR11019 311 409 1.0E-26 T 22-04-2016 L21SP4_RS01615 b06e254d17d861ce45c64b03e4078c3e 410 SMART SM00342 318 401 5.6E-31 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP4_RS01615 b06e254d17d861ce45c64b03e4078c3e 410 SUPERFAMILY SSF46689 354 405 7.62E-14 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS04600 e2be153ebb46c3b53adfebbf5f2597b8 319 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 122 311 1.1E-21 T 22-04-2016 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 L21SP4_RS04600 e2be153ebb46c3b53adfebbf5f2597b8 319 SUPERFAMILY SSF51726 2 312 1.74E-26 T 22-04-2016 L21SP4_RS04600 e2be153ebb46c3b53adfebbf5f2597b8 319 Gene3D G3DSA:3.20.20.210 121 311 3.4E-29 T 22-04-2016 L21SP4_RS02610 c43f5274c51e7f5f8e7b098282000f2f 451 SUPERFAMILY SSF53738 258 361 7.06E-17 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP4_RS02610 c43f5274c51e7f5f8e7b098282000f2f 451 Gene3D G3DSA:3.40.120.10 252 365 5.8E-21 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP4_RS02610 c43f5274c51e7f5f8e7b098282000f2f 451 PANTHER PTHR22573 10 451 1.3E-65 T 22-04-2016 L21SP4_RS02610 c43f5274c51e7f5f8e7b098282000f2f 451 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 259 364 9.7E-18 T 22-04-2016 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP4_RS02610 c43f5274c51e7f5f8e7b098282000f2f 451 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 383 447 4.8E-7 T 22-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP4_RS02610 c43f5274c51e7f5f8e7b098282000f2f 451 Gene3D G3DSA:3.40.120.10 10 138 7.0E-26 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP4_RS02610 c43f5274c51e7f5f8e7b098282000f2f 451 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 153 252 2.6E-16 T 22-04-2016 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP4_RS02610 c43f5274c51e7f5f8e7b098282000f2f 451 SUPERFAMILY SSF53738 151 253 7.46E-13 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP4_RS02610 c43f5274c51e7f5f8e7b098282000f2f 451 PANTHER PTHR22573:SF48 10 451 1.3E-65 T 22-04-2016 L21SP4_RS02610 c43f5274c51e7f5f8e7b098282000f2f 451 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 10 133 5.8E-27 T 22-04-2016 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP4_RS02610 c43f5274c51e7f5f8e7b098282000f2f 451 SUPERFAMILY SSF55957 363 449 7.19E-16 T 22-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP4_RS02610 c43f5274c51e7f5f8e7b098282000f2f 451 SUPERFAMILY SSF53738 9 138 4.71E-29 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP4_RS02610 c43f5274c51e7f5f8e7b098282000f2f 451 Gene3D G3DSA:3.30.310.50 368 449 1.7E-14 T 22-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP4_RS02610 c43f5274c51e7f5f8e7b098282000f2f 451 Gene3D G3DSA:3.40.120.10 172 251 2.2E-8 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP4_RS11425 a5324f555e52fd3e9d5d39bd72774008 559 SUPERFAMILY SSF52540 1 202 2.8E-52 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS11425 a5324f555e52fd3e9d5d39bd72774008 559 SUPERFAMILY SSF52540 289 317 2.8E-52 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS11425 a5324f555e52fd3e9d5d39bd72774008 559 SUPERFAMILY SSF52540 346 514 2.8E-52 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS11425 a5324f555e52fd3e9d5d39bd72774008 559 Gene3D G3DSA:3.40.50.300 374 505 5.1E-5 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS11425 a5324f555e52fd3e9d5d39bd72774008 559 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 552 1.6E-150 T 22-04-2016 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 L21SP4_RS11425 a5324f555e52fd3e9d5d39bd72774008 559 PIRSF PIRSF003128 1 557 4.4E-163 T 22-04-2016 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 L21SP4_RS11425 a5324f555e52fd3e9d5d39bd72774008 559 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 506 5.3E-14 T 22-04-2016 IPR003395 RecF/RecN/SMC, N-terminal L21SP4_RS11425 a5324f555e52fd3e9d5d39bd72774008 559 PANTHER PTHR11059 2 559 1.8E-142 T 22-04-2016 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 L21SP4_RS11425 a5324f555e52fd3e9d5d39bd72774008 559 Gene3D G3DSA:3.40.50.300 1 207 5.0E-57 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS10400 47a74c23b9ac4e10aec9802d4452201e 153 PANTHER PTHR40114 1 148 1.3E-16 T 22-04-2016 L21SP4_RS10400 47a74c23b9ac4e10aec9802d4452201e 153 SUPERFAMILY SSF55154 3 147 7.52E-27 T 22-04-2016 IPR033469 CYTH-like domain L21SP4_RS10400 47a74c23b9ac4e10aec9802d4452201e 153 SMART SM01118 1 151 3.5E-7 T 22-04-2016 IPR023577 CYTH domain L21SP4_RS10400 47a74c23b9ac4e10aec9802d4452201e 153 Gene3D G3DSA:2.40.320.10 4 148 6.5E-35 T 22-04-2016 IPR023577 CYTH domain L21SP4_RS10400 47a74c23b9ac4e10aec9802d4452201e 153 Pfam PF01928 CYTH domain 2 106 1.8E-5 T 22-04-2016 IPR023577 CYTH domain L21SP4_RS10400 47a74c23b9ac4e10aec9802d4452201e 153 PIRSF PIRSF016487 1 153 5.4E-36 T 22-04-2016 IPR012042 Inorganic triphosphatase NeuTTM/CthTTM-like L21SP4_RS07615 4b4658707834cb0bf9a80ae7e98f1bfc 492 Pfam PF01618 MotA/TolQ/ExbB proton channel family 357 474 1.7E-28 T 22-04-2016 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 L21SP4_RS07615 4b4658707834cb0bf9a80ae7e98f1bfc 492 PIRSF PIRSF037714 24 490 1.2E-84 T 22-04-2016 IPR017270 Putative MotA/TolQ/ExbB family protein L21SP4_RS07615 4b4658707834cb0bf9a80ae7e98f1bfc 492 PANTHER PTHR30625:SF0 257 485 2.3E-41 T 22-04-2016 L21SP4_RS07615 4b4658707834cb0bf9a80ae7e98f1bfc 492 PANTHER PTHR30625 257 485 2.3E-41 T 22-04-2016 L21SP4_RS00010 fb7f819a740be90205037d3d8bf74c4b 367 Pfam PF02767 DNA polymerase III beta subunit, central domain 129 244 2.4E-26 T 22-04-2016 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 L21SP4_RS00010 fb7f819a740be90205037d3d8bf74c4b 367 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 246 364 3.2E-27 T 22-04-2016 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 L21SP4_RS00010 fb7f819a740be90205037d3d8bf74c4b 367 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 119 1.2E-31 T 22-04-2016 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 L21SP4_RS00010 fb7f819a740be90205037d3d8bf74c4b 367 PIRSF PIRSF000804 1 366 2.6E-120 T 22-04-2016 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 L21SP4_RS00010 fb7f819a740be90205037d3d8bf74c4b 367 PANTHER PTHR30478 2 367 4.6E-121 T 22-04-2016 L21SP4_RS00010 fb7f819a740be90205037d3d8bf74c4b 367 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 364 4.7E-98 T 22-04-2016 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 L21SP4_RS00010 fb7f819a740be90205037d3d8bf74c4b 367 SUPERFAMILY SSF55979 128 245 1.26E-25 T 22-04-2016 L21SP4_RS00010 fb7f819a740be90205037d3d8bf74c4b 367 SUPERFAMILY SSF55979 246 365 5.34E-31 T 22-04-2016 L21SP4_RS00010 fb7f819a740be90205037d3d8bf74c4b 367 Gene3D G3DSA:3.10.150.10 1 120 4.6E-29 T 22-04-2016 L21SP4_RS00010 fb7f819a740be90205037d3d8bf74c4b 367 SUPERFAMILY SSF55979 1 116 2.98E-25 T 22-04-2016 L21SP4_RS00010 fb7f819a740be90205037d3d8bf74c4b 367 Gene3D G3DSA:3.10.150.10 124 249 1.8E-32 T 22-04-2016 L21SP4_RS00010 fb7f819a740be90205037d3d8bf74c4b 367 SMART SM00480 17 361 5.7E-110 T 22-04-2016 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 L21SP4_RS00010 fb7f819a740be90205037d3d8bf74c4b 367 Gene3D G3DSA:3.10.150.10 250 365 4.6E-32 T 22-04-2016 L21SP4_RS06865 1dc3fe61b70fa74f3bd858939a698233 1298 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 801 920 2.4E-8 T 22-04-2016 IPR000014 PAS domain L21SP4_RS06865 1dc3fe61b70fa74f3bd858939a698233 1298 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 447 578 3.9E-20 T 22-04-2016 IPR000014 PAS domain L21SP4_RS06865 1dc3fe61b70fa74f3bd858939a698233 1298 SUPERFAMILY SSF55874 986 1162 7.07E-40 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS06865 1dc3fe61b70fa74f3bd858939a698233 1298 Gene3D G3DSA:3.30.450.20 441 570 1.4E-26 T 22-04-2016 L21SP4_RS06865 1dc3fe61b70fa74f3bd858939a698233 1298 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 1038 1158 2.0E-19 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS06865 1dc3fe61b70fa74f3bd858939a698233 1298 Gene3D G3DSA:3.40.50.2300 1179 1298 3.3E-24 T 22-04-2016 L21SP4_RS06865 1dc3fe61b70fa74f3bd858939a698233 1298 Gene3D G3DSA:3.30.565.10 1009 1157 5.4E-38 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS06865 1dc3fe61b70fa74f3bd858939a698233 1298 Pfam PF00072 Response regulator receiver domain 1182 1294 4.0E-14 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 L21SP4_RS06865 1dc3fe61b70fa74f3bd858939a698233 1298 Gene3D G3DSA:1.10.287.130 922 992 1.4E-6 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS06865 1dc3fe61b70fa74f3bd858939a698233 1298 PANTHER PTHR24423:SF458 802 1298 6.2E-150 T 22-04-2016 L21SP4_RS06865 1dc3fe61b70fa74f3bd858939a698233 1298 PANTHER PTHR24423:SF458 127 587 6.2E-150 T 22-04-2016 L21SP4_RS06865 1dc3fe61b70fa74f3bd858939a698233 1298 Pfam PF00512 His Kinase A (phospho-acceptor) domain 931 994 6.2E-9 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS06865 1dc3fe61b70fa74f3bd858939a698233 1298 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1144 1157 1.3E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS06865 1dc3fe61b70fa74f3bd858939a698233 1298 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1120 1138 1.3E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS06865 1dc3fe61b70fa74f3bd858939a698233 1298 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1107 1117 1.3E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS06865 1dc3fe61b70fa74f3bd858939a698233 1298 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1089 1103 1.3E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS06865 1dc3fe61b70fa74f3bd858939a698233 1298 SUPERFAMILY SSF55781 293 439 1.26E-9 T 22-04-2016 IPR029016 GAF domain-like L21SP4_RS06865 1dc3fe61b70fa74f3bd858939a698233 1298 SMART SM00091 449 515 2.7E-7 T 22-04-2016 IPR000014 PAS domain L21SP4_RS06865 1dc3fe61b70fa74f3bd858939a698233 1298 SMART SM00091 804 870 3.6 T 22-04-2016 IPR000014 PAS domain L21SP4_RS06865 1dc3fe61b70fa74f3bd858939a698233 1298 SMART SM00086 874 914 9.8 T 22-04-2016 IPR001610 PAC motif L21SP4_RS06865 1dc3fe61b70fa74f3bd858939a698233 1298 SMART SM00086 530 572 1.0E-5 T 22-04-2016 IPR001610 PAC motif L21SP4_RS06865 1dc3fe61b70fa74f3bd858939a698233 1298 PANTHER PTHR24423 802 1298 6.2E-150 T 22-04-2016 L21SP4_RS06865 1dc3fe61b70fa74f3bd858939a698233 1298 PANTHER PTHR24423 127 587 6.2E-150 T 22-04-2016 L21SP4_RS06865 1dc3fe61b70fa74f3bd858939a698233 1298 Pfam PF08448 PAS fold 811 916 1.3E-10 T 22-04-2016 IPR013656 PAS fold-4 L21SP4_RS06865 1dc3fe61b70fa74f3bd858939a698233 1298 Pfam PF08448 PAS fold 456 573 1.7E-14 T 22-04-2016 IPR013656 PAS fold-4 L21SP4_RS06865 1dc3fe61b70fa74f3bd858939a698233 1298 Gene3D G3DSA:3.30.450.40 271 440 4.7E-13 T 22-04-2016 IPR029016 GAF domain-like L21SP4_RS06865 1dc3fe61b70fa74f3bd858939a698233 1298 SUPERFAMILY SSF55785 789 912 1.92E-16 T 22-04-2016 IPR000014 PAS domain L21SP4_RS06865 1dc3fe61b70fa74f3bd858939a698233 1298 SUPERFAMILY SSF55785 437 570 1.74E-25 T 22-04-2016 IPR000014 PAS domain L21SP4_RS06865 1dc3fe61b70fa74f3bd858939a698233 1298 SUPERFAMILY SSF52172 1180 1298 2.56E-22 T 22-04-2016 IPR011006 CheY-like superfamily L21SP4_RS06865 1dc3fe61b70fa74f3bd858939a698233 1298 Gene3D G3DSA:3.30.450.20 794 913 8.4E-16 T 22-04-2016 L21SP4_RS06865 1dc3fe61b70fa74f3bd858939a698233 1298 SMART SM00448 1179 1293 2.8E-16 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 L21SP4_RS06865 1dc3fe61b70fa74f3bd858939a698233 1298 Pfam PF10114 Sensory domain found in PocR 685 789 2.9E-7 T 22-04-2016 IPR018771 PocR domain UniPathway: UPA00148|UniPathway: UPA00621 L21SP4_RS06865 1dc3fe61b70fa74f3bd858939a698233 1298 Pfam PF13185 GAF domain 290 429 7.2E-7 T 22-04-2016 IPR003018 GAF domain GO:0005515 L21SP4_RS06865 1dc3fe61b70fa74f3bd858939a698233 1298 SMART SM00388 929 996 7.7E-8 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS06865 1dc3fe61b70fa74f3bd858939a698233 1298 SMART SM00387 1037 1160 5.4E-31 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS06865 1dc3fe61b70fa74f3bd858939a698233 1298 SUPERFAMILY SSF47384 921 993 1.57E-10 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS05535 1b73b746be97433bf07dc4e2851bc911 390 Pfam PF06439 Domain of Unknown Function (DUF1080) 219 372 2.3E-23 T 22-04-2016 IPR010496 Domain of unknown function DUF1080 L21SP4_RS05535 1b73b746be97433bf07dc4e2851bc911 390 PANTHER PTHR33546 225 372 3.9E-26 T 22-04-2016 L21SP4_RS05535 1b73b746be97433bf07dc4e2851bc911 390 PANTHER PTHR33546:SF1 225 372 3.9E-26 T 22-04-2016 L21SP4_RS07150 34ae62b4d6a78f5a6dbea75e2f81ea92 349 PANTHER PTHR21716 1 347 6.4E-65 T 22-04-2016 IPR002549 Transmembrane protein TqsA-like L21SP4_RS07150 34ae62b4d6a78f5a6dbea75e2f81ea92 349 Pfam PF01594 Domain of unknown function DUF20 12 324 2.4E-58 T 22-04-2016 IPR002549 Transmembrane protein TqsA-like L21SP4_RS05080 c8bd395a882b12e9c4761d85281ccdd7 603 Gene3D G3DSA:3.40.50.300 2 197 1.1E-54 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS05080 c8bd395a882b12e9c4761d85281ccdd7 603 PANTHER PTHR23115:SF97 7 601 6.7E-266 T 22-04-2016 L21SP4_RS05080 c8bd395a882b12e9c4761d85281ccdd7 603 SUPERFAMILY SSF52540 1 229 9.7E-52 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS05080 c8bd395a882b12e9c4761d85281ccdd7 603 Hamap MF_00071 Elongation factor 4 [lepA]. 1 603 265.661 T 22-04-2016 IPR006297 Elongation factor 4 GO:0005525 L21SP4_RS05080 c8bd395a882b12e9c4761d85281ccdd7 603 SUPERFAMILY SSF54980 405 499 1.29E-21 T 22-04-2016 IPR009022 Elongation factor G, III-V domain L21SP4_RS05080 c8bd395a882b12e9c4761d85281ccdd7 603 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 177 2.2E-22 T 22-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 L21SP4_RS05080 c8bd395a882b12e9c4761d85281ccdd7 603 Gene3D G3DSA:2.40.30.10 198 295 1.3E-25 T 22-04-2016 L21SP4_RS05080 c8bd395a882b12e9c4761d85281ccdd7 603 Gene3D G3DSA:3.30.70.240 406 495 1.7E-18 T 22-04-2016 IPR000640 Translation elongation factor EFG, V domain L21SP4_RS05080 c8bd395a882b12e9c4761d85281ccdd7 603 Pfam PF00679 Elongation factor G C-terminus 406 491 2.3E-19 T 22-04-2016 IPR000640 Translation elongation factor EFG, V domain L21SP4_RS05080 c8bd395a882b12e9c4761d85281ccdd7 603 TIGRFAM TIGR01393 lepA: elongation factor 4 6 601 3.1E-280 T 22-04-2016 IPR006297 Elongation factor 4 GO:0005525 L21SP4_RS05080 c8bd395a882b12e9c4761d85281ccdd7 603 Pfam PF03144 Elongation factor Tu domain 2 210 280 4.9E-10 T 22-04-2016 IPR004161 Translation elongation factor EFTu/EF1A, domain 2 GO:0005525 L21SP4_RS05080 c8bd395a882b12e9c4761d85281ccdd7 603 Gene3D G3DSA:3.30.70.870 297 373 4.3E-22 T 22-04-2016 L21SP4_RS05080 c8bd395a882b12e9c4761d85281ccdd7 603 SUPERFAMILY SSF54980 297 375 1.12E-16 T 22-04-2016 IPR009022 Elongation factor G, III-V domain L21SP4_RS05080 c8bd395a882b12e9c4761d85281ccdd7 603 PANTHER PTHR23115 7 601 6.7E-266 T 22-04-2016 L21SP4_RS05080 c8bd395a882b12e9c4761d85281ccdd7 603 Pfam PF06421 GTP-binding protein LepA C-terminus 493 599 4.4E-48 T 22-04-2016 IPR013842 GTP-binding protein LepA, C-terminal L21SP4_RS05080 c8bd395a882b12e9c4761d85281ccdd7 603 Pfam PF00009 Elongation factor Tu GTP binding domain 6 184 6.2E-50 T 22-04-2016 L21SP4_RS05080 c8bd395a882b12e9c4761d85281ccdd7 603 PRINTS PR00315 GTP-binding elongation factor signature 77 87 1.6E-13 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 L21SP4_RS05080 c8bd395a882b12e9c4761d85281ccdd7 603 PRINTS PR00315 GTP-binding elongation factor signature 93 104 1.6E-13 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 L21SP4_RS05080 c8bd395a882b12e9c4761d85281ccdd7 603 PRINTS PR00315 GTP-binding elongation factor signature 9 22 1.6E-13 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 L21SP4_RS05080 c8bd395a882b12e9c4761d85281ccdd7 603 PRINTS PR00315 GTP-binding elongation factor signature 129 138 1.6E-13 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 L21SP4_RS05080 c8bd395a882b12e9c4761d85281ccdd7 603 PRINTS PR00315 GTP-binding elongation factor signature 52 60 1.6E-13 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 L21SP4_RS00670 0e59e8bc795e27ee9eb80531f71e6028 544 Pfam PF00884 Sulfatase 27 440 1.9E-68 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS00670 0e59e8bc795e27ee9eb80531f71e6028 544 PANTHER PTHR10342 384 535 6.6E-129 T 22-04-2016 L21SP4_RS00670 0e59e8bc795e27ee9eb80531f71e6028 544 PANTHER PTHR10342 290 344 6.6E-129 T 22-04-2016 L21SP4_RS00670 0e59e8bc795e27ee9eb80531f71e6028 544 PANTHER PTHR10342 1 234 6.6E-129 T 22-04-2016 L21SP4_RS00670 0e59e8bc795e27ee9eb80531f71e6028 544 PANTHER PTHR10342:SF199 384 535 6.6E-129 T 22-04-2016 L21SP4_RS00670 0e59e8bc795e27ee9eb80531f71e6028 544 PANTHER PTHR10342:SF199 290 344 6.6E-129 T 22-04-2016 L21SP4_RS00670 0e59e8bc795e27ee9eb80531f71e6028 544 PANTHER PTHR10342:SF199 1 234 6.6E-129 T 22-04-2016 L21SP4_RS00670 0e59e8bc795e27ee9eb80531f71e6028 544 ProSitePatterns PS00149 Sulfatases signature 2. 115 125 - T 22-04-2016 IPR024607 Sulfatase, conserved site L21SP4_RS00670 0e59e8bc795e27ee9eb80531f71e6028 544 Gene3D G3DSA:3.30.1120.10 467 537 4.4E-17 T 22-04-2016 L21SP4_RS00670 0e59e8bc795e27ee9eb80531f71e6028 544 SUPERFAMILY SSF53649 287 535 1.57E-122 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS00670 0e59e8bc795e27ee9eb80531f71e6028 544 SUPERFAMILY SSF53649 25 260 1.57E-122 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS00670 0e59e8bc795e27ee9eb80531f71e6028 544 Gene3D G3DSA:3.40.720.10 24 465 1.1E-111 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS09345 84cf1853fa71278861309dc41ef0d0f8 318 SUPERFAMILY SSF111369 47 188 6.67E-11 T 22-04-2016 L21SP4_RS09345 84cf1853fa71278861309dc41ef0d0f8 318 Pfam PF13533 Biotin-lipoyl like 60 96 1.8E-7 T 22-04-2016 L21SP4_RS09345 84cf1853fa71278861309dc41ef0d0f8 318 Pfam PF13437 HlyD family secretion protein 122 210 5.0E-13 T 22-04-2016 L21SP4_RS09345 84cf1853fa71278861309dc41ef0d0f8 318 PANTHER PTHR32347:SF16 1 294 4.0E-32 T 22-04-2016 L21SP4_RS09345 84cf1853fa71278861309dc41ef0d0f8 318 PANTHER PTHR32347 1 294 4.0E-32 T 22-04-2016 L21SP4_RS09345 84cf1853fa71278861309dc41ef0d0f8 318 Gene3D G3DSA:2.40.50.100 59 150 1.8E-12 T 22-04-2016 L21SP4_RS01115 26387439a02d73c9529888c14966276a 106 ProSitePatterns PS00202 Rubredoxin signature. 85 95 - T 22-04-2016 IPR018527 Rubredoxin, iron-binding site GO:0046872 L21SP4_RS01115 26387439a02d73c9529888c14966276a 106 Pfam PF00301 Rubredoxin 55 101 1.7E-15 T 22-04-2016 IPR024935 Rubredoxin domain GO:0005506 L21SP4_RS01115 26387439a02d73c9529888c14966276a 106 SUPERFAMILY SSF57802 55 104 2.02E-17 T 22-04-2016 L21SP4_RS01115 26387439a02d73c9529888c14966276a 106 Gene3D G3DSA:2.20.28.10 55 102 7.8E-20 T 22-04-2016 IPR004039 Rubredoxin-type fold L21SP4_RS01115 26387439a02d73c9529888c14966276a 106 PRINTS PR00163 Rubredoxin signature 55 71 7.5E-9 T 22-04-2016 IPR024935 Rubredoxin domain GO:0005506 L21SP4_RS01115 26387439a02d73c9529888c14966276a 106 PRINTS PR00163 Rubredoxin signature 85 101 7.5E-9 T 22-04-2016 IPR024935 Rubredoxin domain GO:0005506 L21SP4_RS02150 21dc791d05233a16347b90bcdb85f4a4 397 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 21 396 2.0E-74 T 22-04-2016 L21SP4_RS02150 21dc791d05233a16347b90bcdb85f4a4 397 PANTHER PTHR23100 11 396 8.4E-155 T 22-04-2016 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068|UniPathway: UPA00068 L21SP4_RS02150 21dc791d05233a16347b90bcdb85f4a4 397 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 397 131.917 T 22-04-2016 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068|UniPathway: UPA00068 L21SP4_RS02150 21dc791d05233a16347b90bcdb85f4a4 397 Pfam PF01960 ArgJ family 20 396 1.5E-133 T 22-04-2016 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068|UniPathway: UPA00068 L21SP4_RS02150 21dc791d05233a16347b90bcdb85f4a4 397 Gene3D G3DSA:3.60.70.12 10 274 2.5E-98 T 22-04-2016 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068|UniPathway: UPA00068 L21SP4_RS02150 21dc791d05233a16347b90bcdb85f4a4 397 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 11 396 1.7E-121 T 22-04-2016 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068|UniPathway: UPA00068 L21SP4_RS02150 21dc791d05233a16347b90bcdb85f4a4 397 SUPERFAMILY SSF56266 10 396 8.89E-124 T 22-04-2016 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068|UniPathway: UPA00068 L21SP4_RS02150 21dc791d05233a16347b90bcdb85f4a4 397 PANTHER PTHR23100:SF0 11 396 8.4E-155 T 22-04-2016 L21SP4_RS09440 5aa1a6d4ec7ab95bfaba1bbe47b1a37f 1357 Pfam PF00703 Glycosyl hydrolases family 2 614 714 1.7E-8 T 22-04-2016 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 L21SP4_RS09440 5aa1a6d4ec7ab95bfaba1bbe47b1a37f 1357 SUPERFAMILY SSF49303 614 714 3.74E-9 T 22-04-2016 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 L21SP4_RS09440 5aa1a6d4ec7ab95bfaba1bbe47b1a37f 1357 PANTHER PTHR10066 395 555 7.9E-62 T 22-04-2016 L21SP4_RS09440 5aa1a6d4ec7ab95bfaba1bbe47b1a37f 1357 PANTHER PTHR10066 1044 1054 7.9E-62 T 22-04-2016 L21SP4_RS09440 5aa1a6d4ec7ab95bfaba1bbe47b1a37f 1357 PANTHER PTHR10066 576 940 7.9E-62 T 22-04-2016 L21SP4_RS09440 5aa1a6d4ec7ab95bfaba1bbe47b1a37f 1357 PANTHER PTHR10066 996 1011 7.9E-62 T 22-04-2016 L21SP4_RS09440 5aa1a6d4ec7ab95bfaba1bbe47b1a37f 1357 Gene3D G3DSA:2.60.120.260 393 604 4.7E-28 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS09440 5aa1a6d4ec7ab95bfaba1bbe47b1a37f 1357 SUPERFAMILY SSF49785 402 610 5.24E-25 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS09440 5aa1a6d4ec7ab95bfaba1bbe47b1a37f 1357 Gene3D G3DSA:2.60.120.360 207 359 1.3E-12 T 22-04-2016 L21SP4_RS09440 5aa1a6d4ec7ab95bfaba1bbe47b1a37f 1357 Gene3D G3DSA:3.20.20.80 717 1005 4.8E-36 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP4_RS09440 5aa1a6d4ec7ab95bfaba1bbe47b1a37f 1357 SUPERFAMILY SSF49785 212 360 1.87E-10 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS09440 5aa1a6d4ec7ab95bfaba1bbe47b1a37f 1357 Gene3D G3DSA:2.60.40.320 605 715 6.4E-11 T 22-04-2016 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 L21SP4_RS09440 5aa1a6d4ec7ab95bfaba1bbe47b1a37f 1357 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 481 550 1.9E-8 T 22-04-2016 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP4_RS09440 5aa1a6d4ec7ab95bfaba1bbe47b1a37f 1357 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 716 883 1.4E-9 T 22-04-2016 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP4_RS09440 5aa1a6d4ec7ab95bfaba1bbe47b1a37f 1357 SUPERFAMILY SSF51445 711 1029 4.9E-39 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily L21SP4_RS05445 5ef69262c7d2d7459ae30248eacd292a 175 PIRSF PIRSF015617 1 175 5.2E-54 T 22-04-2016 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|UniPathway: UPA00148 L21SP4_RS05445 5ef69262c7d2d7459ae30248eacd292a 175 SUPERFAMILY SSF52540 7 175 3.19E-45 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS05445 5ef69262c7d2d7459ae30248eacd292a 175 PANTHER PTHR30069 4 175 4.0E-39 T 22-04-2016 L21SP4_RS05445 5ef69262c7d2d7459ae30248eacd292a 175 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 7 175 5.2E-54 T 22-04-2016 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|UniPathway: UPA00148 L21SP4_RS05445 5ef69262c7d2d7459ae30248eacd292a 175 Gene3D G3DSA:3.40.50.300 6 175 9.2E-59 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS11025 a376605b04e5f9735fd63c357c1c1bb1 200 PANTHER PTHR33678:SF2 17 191 3.3E-42 T 22-04-2016 L21SP4_RS11025 a376605b04e5f9735fd63c357c1c1bb1 200 Pfam PF13005 zinc-finger binding domain of transposase IS66 116 159 5.4E-8 T 22-04-2016 IPR024474 Zinc-finger binding domain of transposase IS66 L21SP4_RS11025 a376605b04e5f9735fd63c357c1c1bb1 200 PANTHER PTHR33678 17 191 3.3E-42 T 22-04-2016 L21SP4_RS04770 78f344229af7635fb4f95084ca321fe5 348 Pfam PF00368 Hydroxymethylglutaryl-coenzyme A reductase 7 340 2.3E-80 T 22-04-2016 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|UniPathway: UPA00058 L21SP4_RS04770 78f344229af7635fb4f95084ca321fe5 348 PANTHER PTHR10572 25 341 1.3E-92 T 22-04-2016 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|UniPathway: UPA00058 L21SP4_RS04770 78f344229af7635fb4f95084ca321fe5 348 SUPERFAMILY SSF55035 62 176 8.89E-34 T 22-04-2016 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|UniPathway: UPA00058 L21SP4_RS04770 78f344229af7635fb4f95084ca321fe5 348 SUPERFAMILY SSF56542 6 59 3.4E-58 T 22-04-2016 IPR009029 Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain GO:0015936|GO:0016616|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|UniPathway: UPA00058 L21SP4_RS04770 78f344229af7635fb4f95084ca321fe5 348 SUPERFAMILY SSF56542 174 326 3.4E-58 T 22-04-2016 IPR009029 Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain GO:0015936|GO:0016616|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|UniPathway: UPA00058 L21SP4_RS04770 78f344229af7635fb4f95084ca321fe5 348 Gene3D G3DSA:3.30.70.420 62 175 4.5E-34 T 22-04-2016 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|UniPathway: UPA00058 L21SP4_RS04770 78f344229af7635fb4f95084ca321fe5 348 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 260 281 2.8E-35 T 22-04-2016 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|UniPathway: UPA00058 L21SP4_RS04770 78f344229af7635fb4f95084ca321fe5 348 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 157 182 2.8E-35 T 22-04-2016 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|UniPathway: UPA00058 L21SP4_RS04770 78f344229af7635fb4f95084ca321fe5 348 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 208 234 2.8E-35 T 22-04-2016 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|UniPathway: UPA00058 L21SP4_RS04770 78f344229af7635fb4f95084ca321fe5 348 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 117 135 2.8E-35 T 22-04-2016 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|UniPathway: UPA00058 L21SP4_RS04770 78f344229af7635fb4f95084ca321fe5 348 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 28 48 2.8E-35 T 22-04-2016 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|UniPathway: UPA00058 L21SP4_RS04770 78f344229af7635fb4f95084ca321fe5 348 Gene3D G3DSA:3.90.770.10 176 341 1.4E-59 T 22-04-2016 IPR023074 Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|UniPathway: UPA00058 L21SP4_RS04770 78f344229af7635fb4f95084ca321fe5 348 Gene3D G3DSA:3.90.770.10 24 58 1.4E-59 T 22-04-2016 IPR023074 Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|UniPathway: UPA00058 L21SP4_RS09910 0e5ee63400f0dfcde160f0d60d974513 483 PANTHER PTHR11773 2 480 1.5E-207 T 22-04-2016 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2 L21SP4_RS09910 0e5ee63400f0dfcde160f0d60d974513 483 SUPERFAMILY SSF53383 4 478 1.38E-105 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase L21SP4_RS09910 0e5ee63400f0dfcde160f0d60d974513 483 Pfam PF00266 Aminotransferase class-V 161 278 4.7E-9 T 22-04-2016 IPR000192 Aminotransferase class V domain L21SP4_RS09910 0e5ee63400f0dfcde160f0d60d974513 483 Gene3D G3DSA:3.40.640.10 106 283 7.7E-32 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 L21SP4_RS12100 1a9fc157738d7e484aa85f792f715001 406 SUPERFAMILY SSF81901 281 384 6.54E-31 T 22-04-2016 L21SP4_RS12100 1a9fc157738d7e484aa85f792f715001 406 SUPERFAMILY SSF81901 146 242 6.54E-31 T 22-04-2016 L21SP4_RS12100 1a9fc157738d7e484aa85f792f715001 406 SMART SM00028 351 384 0.18 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS12100 1a9fc157738d7e484aa85f792f715001 406 SMART SM00028 283 316 6.5 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS12100 1a9fc157738d7e484aa85f792f715001 406 SMART SM00028 317 350 1.1E-6 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS12100 1a9fc157738d7e484aa85f792f715001 406 SMART SM00028 105 138 3.5 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS12100 1a9fc157738d7e484aa85f792f715001 406 SMART SM00028 71 104 0.34 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS12100 1a9fc157738d7e484aa85f792f715001 406 SMART SM00028 139 172 1.4E-5 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS12100 1a9fc157738d7e484aa85f792f715001 406 Pfam PF13432 Tetratricopeptide repeat 38 104 1.6E-4 T 22-04-2016 L21SP4_RS12100 1a9fc157738d7e484aa85f792f715001 406 Pfam PF13432 Tetratricopeptide repeat 178 242 0.011 T 22-04-2016 L21SP4_RS12100 1a9fc157738d7e484aa85f792f715001 406 Pfam PF13432 Tetratricopeptide repeat 109 173 8.0E-9 T 22-04-2016 L21SP4_RS12100 1a9fc157738d7e484aa85f792f715001 406 SUPERFAMILY SSF48452 73 183 4.55E-19 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS12100 1a9fc157738d7e484aa85f792f715001 406 Gene3D G3DSA:1.25.40.10 35 239 5.5E-37 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS12100 1a9fc157738d7e484aa85f792f715001 406 Gene3D G3DSA:1.25.40.10 273 389 1.4E-25 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS12100 1a9fc157738d7e484aa85f792f715001 406 Pfam PF13414 TPR repeat 332 365 1.2E-8 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS12100 1a9fc157738d7e484aa85f792f715001 406 Pfam PF13414 TPR repeat 293 330 1.3E-9 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS12100 1a9fc157738d7e484aa85f792f715001 406 PANTHER PTHR23083 35 216 1.2E-50 T 22-04-2016 L21SP4_RS12100 1a9fc157738d7e484aa85f792f715001 406 PANTHER PTHR23083 293 395 1.2E-50 T 22-04-2016 L21SP4_RS08555 54c746517ea765ca6cd715a2d99b22d0 179 PANTHER PTHR14119 1 179 2.9E-64 T 22-04-2016 L21SP4_RS08555 54c746517ea765ca6cd715a2d99b22d0 179 SUPERFAMILY SSF52499 2 179 1.7E-44 T 22-04-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 L21SP4_RS08555 54c746517ea765ca6cd715a2d99b22d0 179 Pfam PF00857 Isochorismatase family 8 156 4.0E-28 T 22-04-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 L21SP4_RS08555 54c746517ea765ca6cd715a2d99b22d0 179 Gene3D G3DSA:3.40.50.850 2 179 2.2E-57 T 22-04-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 L21SP4_RS04655 1644f4c2974f0b1e6bd7c3bad2b95bb5 133 Pfam PF02130 Uncharacterized protein family UPF0054 11 113 1.8E-15 T 22-04-2016 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 L21SP4_RS04655 1644f4c2974f0b1e6bd7c3bad2b95bb5 133 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 11 114 4.1E-17 T 22-04-2016 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 L21SP4_RS04655 1644f4c2974f0b1e6bd7c3bad2b95bb5 133 Gene3D G3DSA:3.40.390.30 7 116 2.9E-21 T 22-04-2016 IPR023091 Metalloprotease catalytic domain, predicted GO:0004222 L21SP4_RS04655 1644f4c2974f0b1e6bd7c3bad2b95bb5 133 SUPERFAMILY SSF55486 8 115 2.44E-21 T 22-04-2016 L21SP4_RS01735 3838ffaff9a0bde319500059147ca6cd 1019 SUPERFAMILY SSF81886 723 937 4.05E-64 T 22-04-2016 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 L21SP4_RS01735 3838ffaff9a0bde319500059147ca6cd 1019 SUPERFAMILY SSF81886 997 1009 4.05E-64 T 22-04-2016 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 L21SP4_RS01735 3838ffaff9a0bde319500059147ca6cd 1019 Pfam PF07516 SecA Wing and Scaffold domain 721 925 7.6E-58 T 22-04-2016 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 L21SP4_RS01735 3838ffaff9a0bde319500059147ca6cd 1019 SUPERFAMILY SSF52540 521 720 1.39E-49 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS01735 3838ffaff9a0bde319500059147ca6cd 1019 SUPERFAMILY SSF52540 6 242 6.97E-77 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS01735 3838ffaff9a0bde319500059147ca6cd 1019 SUPERFAMILY SSF52540 472 519 6.97E-77 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS01735 3838ffaff9a0bde319500059147ca6cd 1019 Gene3D G3DSA:3.40.50.300 521 721 7.0E-80 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS01735 3838ffaff9a0bde319500059147ca6cd 1019 Gene3D G3DSA:3.90.1440.10 331 372 7.0E-35 T 22-04-2016 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 L21SP4_RS01735 3838ffaff9a0bde319500059147ca6cd 1019 Gene3D G3DSA:3.90.1440.10 404 472 7.0E-35 T 22-04-2016 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 L21SP4_RS01735 3838ffaff9a0bde319500059147ca6cd 1019 Pfam PF01043 SecA preprotein cross-linking domain 332 462 1.3E-29 T 22-04-2016 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 L21SP4_RS01735 3838ffaff9a0bde319500059147ca6cd 1019 SMART SM00958 299 462 7.0E-21 T 22-04-2016 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 L21SP4_RS01735 3838ffaff9a0bde319500059147ca6cd 1019 SMART SM00957 6 506 1.0E-248 T 22-04-2016 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 L21SP4_RS01735 3838ffaff9a0bde319500059147ca6cd 1019 SUPERFAMILY SSF81767 406 472 1.44E-28 T 22-04-2016 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 L21SP4_RS01735 3838ffaff9a0bde319500059147ca6cd 1019 SUPERFAMILY SSF81767 333 378 1.44E-28 T 22-04-2016 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 L21SP4_RS01735 3838ffaff9a0bde319500059147ca6cd 1019 Hamap MF_01382 Protein translocase subunit SecA [secA]. 5 929 19.624 T 22-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 L21SP4_RS01735 3838ffaff9a0bde319500059147ca6cd 1019 Pfam PF07517 SecA DEAD-like domain 6 505 1.7E-132 T 22-04-2016 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 L21SP4_RS01735 3838ffaff9a0bde319500059147ca6cd 1019 Pfam PF02810 SEC-C motif 1001 1019 1.4E-9 T 22-04-2016 IPR004027 SEC-C motif L21SP4_RS01735 3838ffaff9a0bde319500059147ca6cd 1019 PRINTS PR00906 SecA protein signature 480 497 1.3E-56 T 22-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 L21SP4_RS01735 3838ffaff9a0bde319500059147ca6cd 1019 PRINTS PR00906 SecA protein signature 114 128 1.3E-56 T 22-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 L21SP4_RS01735 3838ffaff9a0bde319500059147ca6cd 1019 PRINTS PR00906 SecA protein signature 517 530 1.3E-56 T 22-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 L21SP4_RS01735 3838ffaff9a0bde319500059147ca6cd 1019 PRINTS PR00906 SecA protein signature 130 140 1.3E-56 T 22-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 L21SP4_RS01735 3838ffaff9a0bde319500059147ca6cd 1019 PRINTS PR00906 SecA protein signature 63 87 1.3E-56 T 22-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 L21SP4_RS01735 3838ffaff9a0bde319500059147ca6cd 1019 PRINTS PR00906 SecA protein signature 183 203 1.3E-56 T 22-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 L21SP4_RS01735 3838ffaff9a0bde319500059147ca6cd 1019 PRINTS PR00906 SecA protein signature 443 465 1.3E-56 T 22-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 L21SP4_RS01735 3838ffaff9a0bde319500059147ca6cd 1019 PANTHER PTHR30612 653 1019 0.0 T 22-04-2016 L21SP4_RS01735 3838ffaff9a0bde319500059147ca6cd 1019 PANTHER PTHR30612 1 323 0.0 T 22-04-2016 L21SP4_RS01735 3838ffaff9a0bde319500059147ca6cd 1019 PANTHER PTHR30612 393 624 0.0 T 22-04-2016 L21SP4_RS01735 3838ffaff9a0bde319500059147ca6cd 1019 Gene3D G3DSA:1.10.3060.10 751 926 8.1E-47 T 22-04-2016 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 L21SP4_RS01735 3838ffaff9a0bde319500059147ca6cd 1019 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 28 915 6.3E-304 T 22-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 L21SP4_RS01735 3838ffaff9a0bde319500059147ca6cd 1019 ProSitePatterns PS01312 SecA family signature. 604 619 - T 22-04-2016 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 L21SP4_RS01735 3838ffaff9a0bde319500059147ca6cd 1019 Gene3D G3DSA:3.40.50.300 473 520 5.3E-122 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS01735 3838ffaff9a0bde319500059147ca6cd 1019 Gene3D G3DSA:3.40.50.300 4 242 5.3E-122 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS08370 ec695e33ac309a122c633802c9b17792 139 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 3 128 9.1E-58 T 22-04-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 L21SP4_RS08370 ec695e33ac309a122c633802c9b17792 139 SUPERFAMILY SSF54686 2 137 1.31E-56 T 22-04-2016 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 L21SP4_RS08370 ec695e33ac309a122c633802c9b17792 139 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 83 94 - T 22-04-2016 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS08370 ec695e33ac309a122c633802c9b17792 139 PRINTS PR00060 Ribosomal protein L16 signature 59 88 9.8E-37 T 22-04-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 L21SP4_RS08370 ec695e33ac309a122c633802c9b17792 139 PRINTS PR00060 Ribosomal protein L16 signature 43 54 9.8E-37 T 22-04-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 L21SP4_RS08370 ec695e33ac309a122c633802c9b17792 139 PRINTS PR00060 Ribosomal protein L16 signature 89 118 9.8E-37 T 22-04-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 L21SP4_RS08370 ec695e33ac309a122c633802c9b17792 139 PRINTS PR00060 Ribosomal protein L16 signature 25 37 9.8E-37 T 22-04-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 L21SP4_RS08370 ec695e33ac309a122c633802c9b17792 139 PANTHER PTHR12220 3 136 6.6E-73 T 22-04-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 L21SP4_RS08370 ec695e33ac309a122c633802c9b17792 139 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 60 71 - T 22-04-2016 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS08370 ec695e33ac309a122c633802c9b17792 139 Pfam PF00252 Ribosomal protein L16p/L10e 5 133 8.7E-49 T 22-04-2016 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 L21SP4_RS08370 ec695e33ac309a122c633802c9b17792 139 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 2 135 37.945 T 22-04-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 L21SP4_RS08370 ec695e33ac309a122c633802c9b17792 139 Gene3D G3DSA:3.90.1170.10 24 136 6.3E-53 T 22-04-2016 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 L21SP4_RS10685 39e988c6732a0c3dea9465f139eaeb5a 227 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 5 223 1.2E-59 T 22-04-2016 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 L21SP4_RS10685 39e988c6732a0c3dea9465f139eaeb5a 227 PANTHER PTHR21091:SF18 5 200 3.4E-58 T 22-04-2016 L21SP4_RS10685 39e988c6732a0c3dea9465f139eaeb5a 227 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 83 94 - T 22-04-2016 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 L21SP4_RS10685 39e988c6732a0c3dea9465f139eaeb5a 227 Gene3D G3DSA:3.40.1010.10 5 112 9.3E-12 T 22-04-2016 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 L21SP4_RS10685 39e988c6732a0c3dea9465f139eaeb5a 227 PANTHER PTHR21091 5 200 3.4E-58 T 22-04-2016 L21SP4_RS10685 39e988c6732a0c3dea9465f139eaeb5a 227 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 5 203 1.4E-26 T 22-04-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 L21SP4_RS10685 39e988c6732a0c3dea9465f139eaeb5a 227 Gene3D G3DSA:3.30.950.10 113 225 2.1E-34 T 22-04-2016 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 L21SP4_RS10685 39e988c6732a0c3dea9465f139eaeb5a 227 PIRSF PIRSF005917 1 227 9.9E-82 T 22-04-2016 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 L21SP4_RS10685 39e988c6732a0c3dea9465f139eaeb5a 227 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 4 224 33.297 T 22-04-2016 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 L21SP4_RS10685 39e988c6732a0c3dea9465f139eaeb5a 227 SUPERFAMILY SSF53790 5 222 3.01E-70 T 22-04-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 L21SP4_RS09710 bc045cd7b58fd1c6c826529b1059e62f 497 Pfam PF00665 Integrase core domain 126 258 6.1E-13 T 22-04-2016 IPR001584 Integrase, catalytic core GO:0015074 L21SP4_RS09710 bc045cd7b58fd1c6c826529b1059e62f 497 PANTHER PTHR35004 89 395 2.6E-20 T 22-04-2016 L21SP4_RS09710 bc045cd7b58fd1c6c826529b1059e62f 497 SUPERFAMILY SSF53098 126 292 3.54E-8 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS09710 bc045cd7b58fd1c6c826529b1059e62f 497 ProDom PD043187 TRANSPOSASE PLASMID CATALYTIC INTEGRASE DNA-BINDING DNA TRANSPOSITION RECOMBINATION FOR INSERTION 24 130 6.0E-15 T 22-04-2016 L21SP4_RS09710 bc045cd7b58fd1c6c826529b1059e62f 497 Gene3D G3DSA:3.30.420.10 126 293 2.0E-10 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS09710 bc045cd7b58fd1c6c826529b1059e62f 497 PANTHER PTHR35004:SF2 89 395 2.6E-20 T 22-04-2016 L21SP4_RS03320 bc045cd7b58fd1c6c826529b1059e62f 497 Pfam PF00665 Integrase core domain 126 258 6.1E-13 T 22-04-2016 IPR001584 Integrase, catalytic core GO:0015074 L21SP4_RS03320 bc045cd7b58fd1c6c826529b1059e62f 497 PANTHER PTHR35004 89 395 2.6E-20 T 22-04-2016 L21SP4_RS03320 bc045cd7b58fd1c6c826529b1059e62f 497 SUPERFAMILY SSF53098 126 292 3.54E-8 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS03320 bc045cd7b58fd1c6c826529b1059e62f 497 ProDom PD043187 TRANSPOSASE PLASMID CATALYTIC INTEGRASE DNA-BINDING DNA TRANSPOSITION RECOMBINATION FOR INSERTION 24 130 6.0E-15 T 22-04-2016 L21SP4_RS03320 bc045cd7b58fd1c6c826529b1059e62f 497 Gene3D G3DSA:3.30.420.10 126 293 2.0E-10 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS03320 bc045cd7b58fd1c6c826529b1059e62f 497 PANTHER PTHR35004:SF2 89 395 2.6E-20 T 22-04-2016 L21SP4_RS01850 bc045cd7b58fd1c6c826529b1059e62f 497 Pfam PF00665 Integrase core domain 126 258 6.1E-13 T 22-04-2016 IPR001584 Integrase, catalytic core GO:0015074 L21SP4_RS01850 bc045cd7b58fd1c6c826529b1059e62f 497 PANTHER PTHR35004 89 395 2.6E-20 T 22-04-2016 L21SP4_RS01850 bc045cd7b58fd1c6c826529b1059e62f 497 SUPERFAMILY SSF53098 126 292 3.54E-8 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS01850 bc045cd7b58fd1c6c826529b1059e62f 497 ProDom PD043187 TRANSPOSASE PLASMID CATALYTIC INTEGRASE DNA-BINDING DNA TRANSPOSITION RECOMBINATION FOR INSERTION 24 130 6.0E-15 T 22-04-2016 L21SP4_RS01850 bc045cd7b58fd1c6c826529b1059e62f 497 Gene3D G3DSA:3.30.420.10 126 293 2.0E-10 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS01850 bc045cd7b58fd1c6c826529b1059e62f 497 PANTHER PTHR35004:SF2 89 395 2.6E-20 T 22-04-2016 L21SP4_RS09820 bc045cd7b58fd1c6c826529b1059e62f 497 Pfam PF00665 Integrase core domain 126 258 6.1E-13 T 22-04-2016 IPR001584 Integrase, catalytic core GO:0015074 L21SP4_RS09820 bc045cd7b58fd1c6c826529b1059e62f 497 PANTHER PTHR35004 89 395 2.6E-20 T 22-04-2016 L21SP4_RS09820 bc045cd7b58fd1c6c826529b1059e62f 497 SUPERFAMILY SSF53098 126 292 3.54E-8 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS09820 bc045cd7b58fd1c6c826529b1059e62f 497 ProDom PD043187 TRANSPOSASE PLASMID CATALYTIC INTEGRASE DNA-BINDING DNA TRANSPOSITION RECOMBINATION FOR INSERTION 24 130 6.0E-15 T 22-04-2016 L21SP4_RS09820 bc045cd7b58fd1c6c826529b1059e62f 497 Gene3D G3DSA:3.30.420.10 126 293 2.0E-10 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS09820 bc045cd7b58fd1c6c826529b1059e62f 497 PANTHER PTHR35004:SF2 89 395 2.6E-20 T 22-04-2016 L21SP4_RS10555 9d2a4275dd7e488cb74a5aa6188d19e9 264 SUPERFAMILY SSF52540 7 252 4.21E-64 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS10555 9d2a4275dd7e488cb74a5aa6188d19e9 264 PANTHER PTHR13696 7 263 4.2E-83 T 22-04-2016 L21SP4_RS10555 9d2a4275dd7e488cb74a5aa6188d19e9 264 Pfam PF13614 AAA domain 4 179 2.9E-56 T 22-04-2016 IPR025669 AAA domain L21SP4_RS10555 9d2a4275dd7e488cb74a5aa6188d19e9 264 PRINTS PR00091 Nitrogenase component II signature 32 47 5.8E-5 T 22-04-2016 IPR000392 Nitrogenase iron protein, subunit NifH/Protochlorophyllide reductase, subunit ChlL GO:0005524|GO:0016491|GO:0055114 L21SP4_RS10555 9d2a4275dd7e488cb74a5aa6188d19e9 264 PRINTS PR00091 Nitrogenase component II signature 10 23 5.8E-5 T 22-04-2016 IPR000392 Nitrogenase iron protein, subunit NifH/Protochlorophyllide reductase, subunit ChlL GO:0005524|GO:0016491|GO:0055114 L21SP4_RS10555 9d2a4275dd7e488cb74a5aa6188d19e9 264 Gene3D G3DSA:3.40.50.300 7 254 2.5E-68 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS10555 9d2a4275dd7e488cb74a5aa6188d19e9 264 PANTHER PTHR13696:SF52 7 263 4.2E-83 T 22-04-2016 L21SP4_RS03160 85f6e5f7cde9349061577e01ee5cbba4 271 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 266 1.3E-45 T 22-04-2016 L21SP4_RS03160 85f6e5f7cde9349061577e01ee5cbba4 271 SUPERFAMILY SSF51735 9 267 6.99E-64 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS03160 85f6e5f7cde9349061577e01ee5cbba4 271 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 152 180 - T 22-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 L21SP4_RS03160 85f6e5f7cde9349061577e01ee5cbba4 271 Gene3D G3DSA:3.40.50.720 3 268 9.9E-65 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS03160 85f6e5f7cde9349061577e01ee5cbba4 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 189 206 1.4E-27 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS03160 85f6e5f7cde9349061577e01ee5cbba4 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 1.4E-27 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS03160 85f6e5f7cde9349061577e01ee5cbba4 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 184 1.4E-27 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS03160 85f6e5f7cde9349061577e01ee5cbba4 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 139 155 1.4E-27 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS03160 85f6e5f7cde9349061577e01ee5cbba4 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 1.4E-27 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS03160 85f6e5f7cde9349061577e01ee5cbba4 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 229 249 1.4E-27 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS03160 85f6e5f7cde9349061577e01ee5cbba4 271 PANTHER PTHR24322 14 149 1.2E-40 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS03160 85f6e5f7cde9349061577e01ee5cbba4 271 PANTHER PTHR24322 165 200 1.2E-40 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS03160 85f6e5f7cde9349061577e01ee5cbba4 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 153 8.1E-10 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS03160 85f6e5f7cde9349061577e01ee5cbba4 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 165 184 8.1E-10 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS03160 85f6e5f7cde9349061577e01ee5cbba4 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 8.1E-10 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS03160 85f6e5f7cde9349061577e01ee5cbba4 271 PANTHER PTHR24322:SF625 14 149 1.2E-40 T 22-04-2016 L21SP4_RS03160 85f6e5f7cde9349061577e01ee5cbba4 271 PANTHER PTHR24322:SF625 165 200 1.2E-40 T 22-04-2016 L21SP4_RS02250 bb0ce2338fcae92332ac986a445645e2 515 Pfam PF03129 Anticodon binding domain 417 506 1.2E-20 T 22-04-2016 IPR004154 Anticodon-binding L21SP4_RS02250 bb0ce2338fcae92332ac986a445645e2 515 Gene3D G3DSA:3.40.50.800 413 509 5.7E-39 T 22-04-2016 IPR004154 Anticodon-binding L21SP4_RS02250 bb0ce2338fcae92332ac986a445645e2 515 PANTHER PTHR10745:SF7 404 510 2.8E-210 T 22-04-2016 L21SP4_RS02250 bb0ce2338fcae92332ac986a445645e2 515 PANTHER PTHR10745:SF7 141 386 2.8E-210 T 22-04-2016 L21SP4_RS02250 bb0ce2338fcae92332ac986a445645e2 515 PANTHER PTHR10745:SF7 8 119 2.8E-210 T 22-04-2016 L21SP4_RS02250 bb0ce2338fcae92332ac986a445645e2 515 SUPERFAMILY SSF55681 8 376 2.21E-110 T 22-04-2016 L21SP4_RS02250 bb0ce2338fcae92332ac986a445645e2 515 SUPERFAMILY SSF55681 404 420 2.21E-110 T 22-04-2016 L21SP4_RS02250 bb0ce2338fcae92332ac986a445645e2 515 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 197 371 8.8E-11 T 22-04-2016 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 L21SP4_RS02250 bb0ce2338fcae92332ac986a445645e2 515 PRINTS PR01043 Glycyl-tRNA synthetase signature 177 189 1.7E-55 T 22-04-2016 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 L21SP4_RS02250 bb0ce2338fcae92332ac986a445645e2 515 PRINTS PR01043 Glycyl-tRNA synthetase signature 198 215 1.7E-55 T 22-04-2016 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 L21SP4_RS02250 bb0ce2338fcae92332ac986a445645e2 515 PRINTS PR01043 Glycyl-tRNA synthetase signature 29 43 1.7E-55 T 22-04-2016 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 L21SP4_RS02250 bb0ce2338fcae92332ac986a445645e2 515 PRINTS PR01043 Glycyl-tRNA synthetase signature 247 257 1.7E-55 T 22-04-2016 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 L21SP4_RS02250 bb0ce2338fcae92332ac986a445645e2 515 PRINTS PR01043 Glycyl-tRNA synthetase signature 455 474 1.7E-55 T 22-04-2016 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 L21SP4_RS02250 bb0ce2338fcae92332ac986a445645e2 515 PRINTS PR01043 Glycyl-tRNA synthetase signature 354 366 1.7E-55 T 22-04-2016 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 L21SP4_RS02250 bb0ce2338fcae92332ac986a445645e2 515 PRINTS PR01043 Glycyl-tRNA synthetase signature 230 247 1.7E-55 T 22-04-2016 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 L21SP4_RS02250 bb0ce2338fcae92332ac986a445645e2 515 Hamap MF_00253_B Glycine--tRNA ligase [glyQS]. 7 510 48.064 T 22-04-2016 IPR022961 Glycine-tRNA ligase, bacterial GO:0004820 KEGG: 00970+6.1.1.14 L21SP4_RS02250 bb0ce2338fcae92332ac986a445645e2 515 SUPERFAMILY SSF52954 404 509 1.08E-31 T 22-04-2016 IPR004154 Anticodon-binding L21SP4_RS02250 bb0ce2338fcae92332ac986a445645e2 515 PANTHER PTHR10745 404 510 2.8E-210 T 22-04-2016 IPR027031 Glycyl-tRNA synthetase/DNA polymerase subunit gamma-2 KEGG: 00970+6.1.1.14 L21SP4_RS02250 bb0ce2338fcae92332ac986a445645e2 515 PANTHER PTHR10745 141 386 2.8E-210 T 22-04-2016 IPR027031 Glycyl-tRNA synthetase/DNA polymerase subunit gamma-2 KEGG: 00970+6.1.1.14 L21SP4_RS02250 bb0ce2338fcae92332ac986a445645e2 515 PANTHER PTHR10745 8 119 2.8E-210 T 22-04-2016 IPR027031 Glycyl-tRNA synthetase/DNA polymerase subunit gamma-2 KEGG: 00970+6.1.1.14 L21SP4_RS02250 bb0ce2338fcae92332ac986a445645e2 515 Gene3D G3DSA:3.30.930.10 12 95 4.6E-137 T 22-04-2016 L21SP4_RS02250 bb0ce2338fcae92332ac986a445645e2 515 Gene3D G3DSA:3.30.930.10 162 412 4.6E-137 T 22-04-2016 L21SP4_RS02250 bb0ce2338fcae92332ac986a445645e2 515 TIGRFAM TIGR00389 glyS_dimeric: glycine--tRNA ligase 9 277 1.9E-79 T 22-04-2016 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 L21SP4_RS10805 1967e9a9e90fc9dec55ebe072a4b820e 452 SUPERFAMILY SSF47005 143 186 1.23E-8 T 22-04-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 L21SP4_RS10805 1967e9a9e90fc9dec55ebe072a4b820e 452 Pfam PF00364 Biotin-requiring enzyme 4 74 2.6E-20 T 22-04-2016 IPR000089 Biotin/lipoyl attachment L21SP4_RS10805 1967e9a9e90fc9dec55ebe072a4b820e 452 Pfam PF02817 e3 binding domain 147 181 7.5E-10 T 22-04-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 L21SP4_RS10805 1967e9a9e90fc9dec55ebe072a4b820e 452 SUPERFAMILY SSF52777 208 448 7.56E-78 T 22-04-2016 L21SP4_RS10805 1967e9a9e90fc9dec55ebe072a4b820e 452 Gene3D G3DSA:3.30.559.10 213 448 1.4E-80 T 22-04-2016 IPR023213 Chloramphenicol acetyltransferase-like domain L21SP4_RS10805 1967e9a9e90fc9dec55ebe072a4b820e 452 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 22-04-2016 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site L21SP4_RS10805 1967e9a9e90fc9dec55ebe072a4b820e 452 PANTHER PTHR23151:SF68 5 451 2.4E-166 T 22-04-2016 L21SP4_RS10805 1967e9a9e90fc9dec55ebe072a4b820e 452 SUPERFAMILY SSF51230 2 92 2.88E-21 T 22-04-2016 IPR011053 Single hybrid motif L21SP4_RS10805 1967e9a9e90fc9dec55ebe072a4b820e 452 Gene3D G3DSA:4.10.320.10 143 185 4.7E-13 T 22-04-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 L21SP4_RS10805 1967e9a9e90fc9dec55ebe072a4b820e 452 Gene3D G3DSA:2.40.50.100 1 95 8.5E-21 T 22-04-2016 L21SP4_RS10805 1967e9a9e90fc9dec55ebe072a4b820e 452 PANTHER PTHR23151 5 451 2.4E-166 T 22-04-2016 L21SP4_RS10805 1967e9a9e90fc9dec55ebe072a4b820e 452 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 219 448 1.7E-79 T 22-04-2016 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 L21SP4_RS02125 80d00a02961665a0732bc9e3fe8bc579 577 Gene3D G3DSA:1.20.1560.10 9 325 6.3E-69 T 22-04-2016 L21SP4_RS02125 80d00a02961665a0732bc9e3fe8bc579 577 SUPERFAMILY SSF90123 9 323 2.09E-69 T 22-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 L21SP4_RS02125 80d00a02961665a0732bc9e3fe8bc579 577 Pfam PF00664 ABC transporter transmembrane region 42 273 2.6E-42 T 22-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 L21SP4_RS02125 80d00a02961665a0732bc9e3fe8bc579 577 PANTHER PTHR24221 5 576 1.5E-216 T 22-04-2016 L21SP4_RS02125 80d00a02961665a0732bc9e3fe8bc579 577 Pfam PF00005 ABC transporter 352 501 1.0E-33 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 L21SP4_RS02125 80d00a02961665a0732bc9e3fe8bc579 577 SUPERFAMILY SSF52540 329 572 4.77E-90 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS02125 80d00a02961665a0732bc9e3fe8bc579 577 ProSitePatterns PS00211 ABC transporters family signature. 473 487 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 L21SP4_RS02125 80d00a02961665a0732bc9e3fe8bc579 577 Gene3D G3DSA:3.40.50.300 337 565 8.7E-81 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS02125 80d00a02961665a0732bc9e3fe8bc579 577 SMART SM00382 361 547 5.1E-17 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS10480 3ac2f2e07d385cb781835a71c0a0f722 261 SUPERFAMILY SSF46689 210 260 5.82E-13 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS10480 3ac2f2e07d385cb781835a71c0a0f722 261 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 226 241 8.3E-5 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 L21SP4_RS10480 3ac2f2e07d385cb781835a71c0a0f722 261 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 241 257 8.3E-5 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 L21SP4_RS10480 3ac2f2e07d385cb781835a71c0a0f722 261 SMART SM00342 173 257 6.3E-26 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP4_RS10480 3ac2f2e07d385cb781835a71c0a0f722 261 PANTHER PTHR11019 35 261 1.5E-21 T 22-04-2016 L21SP4_RS10480 3ac2f2e07d385cb781835a71c0a0f722 261 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 211 253 - T 22-04-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 L21SP4_RS10480 3ac2f2e07d385cb781835a71c0a0f722 261 Gene3D G3DSA:1.10.10.60 161 211 1.1E-6 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS10480 3ac2f2e07d385cb781835a71c0a0f722 261 Pfam PF12833 Helix-turn-helix domain 181 259 1.7E-22 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP4_RS10480 3ac2f2e07d385cb781835a71c0a0f722 261 Gene3D G3DSA:1.10.10.60 212 260 3.2E-17 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS10480 3ac2f2e07d385cb781835a71c0a0f722 261 SUPERFAMILY SSF51215 4 133 3.92E-5 T 22-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 L21SP4_RS02935 08c78b9f1d056148fcdfc911befe9b83 551 Pfam PF01676 Metalloenzyme superfamily 16 537 1.1E-68 T 22-04-2016 IPR006124 Metalloenzyme GO:0003824|GO:0046872 L21SP4_RS02935 08c78b9f1d056148fcdfc911befe9b83 551 SUPERFAMILY SSF53649 331 543 2.21E-52 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS02935 08c78b9f1d056148fcdfc911befe9b83 551 SUPERFAMILY SSF53649 16 89 2.21E-52 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS02935 08c78b9f1d056148fcdfc911befe9b83 551 Gene3D G3DSA:3.40.720.10 16 89 2.0E-63 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS02935 08c78b9f1d056148fcdfc911befe9b83 551 Gene3D G3DSA:3.40.720.10 335 543 2.0E-63 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS02935 08c78b9f1d056148fcdfc911befe9b83 551 SUPERFAMILY SSF64158 89 326 9.81E-68 T 22-04-2016 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 L21SP4_RS02935 08c78b9f1d056148fcdfc911befe9b83 551 Gene3D G3DSA:3.40.1450.10 90 326 6.8E-75 T 22-04-2016 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 L21SP4_RS02935 08c78b9f1d056148fcdfc911befe9b83 551 PANTHER PTHR31637:SF0 2 550 2.7E-259 T 22-04-2016 L21SP4_RS02935 08c78b9f1d056148fcdfc911befe9b83 551 PIRSF PIRSF001492 10 550 1.6E-168 T 22-04-2016 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 L21SP4_RS02935 08c78b9f1d056148fcdfc911befe9b83 551 Pfam PF06415 BPG-independent PGAM N-terminus (iPGM_N) 94 317 1.1E-64 T 22-04-2016 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 L21SP4_RS02935 08c78b9f1d056148fcdfc911befe9b83 551 TIGRFAM TIGR01307 pgm_bpd_ind: phosphoglycerate mutase (2,3-diphosphoglycerate-independent) 16 544 2.4E-126 T 22-04-2016 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 L21SP4_RS02935 08c78b9f1d056148fcdfc911befe9b83 551 PANTHER PTHR31637 2 550 2.7E-259 T 22-04-2016 L21SP4_RS10335 bb7f303e0253849a44034075eacacf83 352 Pfam PF00217 ATP:guanido phosphotransferase, C-terminal catalytic domain 23 250 5.1E-69 T 22-04-2016 IPR022414 ATP:guanido phosphotransferase, catalytic domain GO:0016301|GO:0016772 Reactome: REACT_13 L21SP4_RS10335 bb7f303e0253849a44034075eacacf83 352 SUPERFAMILY SSF55931 19 265 6.17E-72 T 22-04-2016 L21SP4_RS10335 bb7f303e0253849a44034075eacacf83 352 PANTHER PTHR11547 23 252 3.6E-76 T 22-04-2016 IPR000749 ATP:guanido phosphotransferase GO:0016772 Reactome: REACT_13 L21SP4_RS10335 bb7f303e0253849a44034075eacacf83 352 PANTHER PTHR11547 305 346 3.6E-76 T 22-04-2016 IPR000749 ATP:guanido phosphotransferase GO:0016772 Reactome: REACT_13 L21SP4_RS10335 bb7f303e0253849a44034075eacacf83 352 PANTHER PTHR11547:SF23 23 252 3.6E-76 T 22-04-2016 L21SP4_RS10335 bb7f303e0253849a44034075eacacf83 352 PANTHER PTHR11547:SF23 305 346 3.6E-76 T 22-04-2016 L21SP4_RS10335 bb7f303e0253849a44034075eacacf83 352 ProSitePatterns PS00112 Phosphagen kinase active site signature. 164 170 - T 22-04-2016 IPR022415 ATP:guanido phosphotransferase active site GO:0016301|GO:0016772 Reactome: REACT_13 L21SP4_RS10335 bb7f303e0253849a44034075eacacf83 352 Gene3D G3DSA:3.30.590.10 16 252 1.9E-66 T 22-04-2016 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 Reactome: REACT_13 L21SP4_RS08405 13e2667eb1ce108889b846bdb4bdd486 215 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 3 204 1.3E-80 T 22-04-2016 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS08405 13e2667eb1ce108889b846bdb4bdd486 215 ProSitePatterns PS00474 Ribosomal protein L3 signature. 102 125 - T 22-04-2016 IPR019926 Ribosomal protein L3, conserved site L21SP4_RS08405 13e2667eb1ce108889b846bdb4bdd486 215 Gene3D G3DSA:2.40.30.10 158 211 9.0E-14 T 22-04-2016 L21SP4_RS08405 13e2667eb1ce108889b846bdb4bdd486 215 Gene3D G3DSA:2.40.30.10 3 32 9.0E-14 T 22-04-2016 L21SP4_RS08405 13e2667eb1ce108889b846bdb4bdd486 215 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 1 207 37.074 T 22-04-2016 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS08405 13e2667eb1ce108889b846bdb4bdd486 215 Gene3D G3DSA:4.10.960.10 77 157 4.8E-29 T 22-04-2016 L21SP4_RS08405 13e2667eb1ce108889b846bdb4bdd486 215 SUPERFAMILY SSF50447 1 210 2.12E-73 T 22-04-2016 IPR009000 Translation protein, beta-barrel domain L21SP4_RS08405 13e2667eb1ce108889b846bdb4bdd486 215 Pfam PF00297 Ribosomal protein L3 98 184 1.3E-15 T 22-04-2016 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS08405 13e2667eb1ce108889b846bdb4bdd486 215 PANTHER PTHR11229 1 208 5.8E-92 T 22-04-2016 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS08335 c034425dd92e84bf599ab7930df79585 133 Pfam PF00410 Ribosomal protein S8 5 133 5.3E-48 T 22-04-2016 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 L21SP4_RS08335 c034425dd92e84bf599ab7930df79585 133 Gene3D G3DSA:3.30.1370.30 3 71 1.4E-25 T 22-04-2016 L21SP4_RS08335 c034425dd92e84bf599ab7930df79585 133 SUPERFAMILY SSF56047 3 133 1.26E-46 T 22-04-2016 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 L21SP4_RS08335 c034425dd92e84bf599ab7930df79585 133 ProSitePatterns PS00053 Ribosomal protein S8 signature. 103 120 - T 22-04-2016 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 L21SP4_RS08335 c034425dd92e84bf599ab7930df79585 133 PANTHER PTHR11758 1 133 2.8E-54 T 22-04-2016 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 L21SP4_RS08335 c034425dd92e84bf599ab7930df79585 133 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 133 32.155 T 22-04-2016 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 L21SP4_RS08335 c034425dd92e84bf599ab7930df79585 133 Gene3D G3DSA:3.30.1490.10 77 133 5.8E-28 T 22-04-2016 L21SP4_RS08455 57169c32e861077860a3e30e0b798927 141 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 3 141 3.3E-63 T 22-04-2016 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 L21SP4_RS08455 57169c32e861077860a3e30e0b798927 141 Gene3D G3DSA:3.30.1550.10 3 71 1.5E-38 T 22-04-2016 IPR020784 Ribosomal protein L11, N-terminal L21SP4_RS08455 57169c32e861077860a3e30e0b798927 141 SUPERFAMILY SSF54747 3 71 5.49E-30 T 22-04-2016 IPR020784 Ribosomal protein L11, N-terminal L21SP4_RS08455 57169c32e861077860a3e30e0b798927 141 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 36 73 3.0E-12 T 22-04-2016 L21SP4_RS08455 57169c32e861077860a3e30e0b798927 141 PANTHER PTHR11661 1 139 1.8E-66 T 22-04-2016 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 L21SP4_RS08455 57169c32e861077860a3e30e0b798927 141 Gene3D G3DSA:1.10.10.250 72 139 7.1E-30 T 22-04-2016 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 L21SP4_RS08455 57169c32e861077860a3e30e0b798927 141 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 5 141 30.933 T 22-04-2016 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 L21SP4_RS08455 57169c32e861077860a3e30e0b798927 141 SUPERFAMILY SSF46906 68 139 1.7E-24 T 22-04-2016 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 L21SP4_RS08455 57169c32e861077860a3e30e0b798927 141 Pfam PF03946 Ribosomal protein L11, N-terminal domain 9 66 2.1E-31 T 22-04-2016 IPR020784 Ribosomal protein L11, N-terminal L21SP4_RS08455 57169c32e861077860a3e30e0b798927 141 SMART SM00649 9 140 2.5E-80 T 22-04-2016 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 L21SP4_RS08455 57169c32e861077860a3e30e0b798927 141 Pfam PF00298 Ribosomal protein L11, RNA binding domain 71 139 1.2E-23 T 22-04-2016 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 L21SP4_RS02705 28baced8b7113148f9aa4f3da6a1a9ab 579 Hamap MF_01810 Membrane protein insertase YidC [yidC]. 5 574 18.79 T 22-04-2016 IPR019998 Membrane insertase YidC GO:0016021|GO:0051205 L21SP4_RS02705 28baced8b7113148f9aa4f3da6a1a9ab 579 PRINTS PR01900 YidC translocation/secretion protein signature 508 523 3.8E-16 T 22-04-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 L21SP4_RS02705 28baced8b7113148f9aa4f3da6a1a9ab 579 PRINTS PR01900 YidC translocation/secretion protein signature 527 551 3.8E-16 T 22-04-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 L21SP4_RS02705 28baced8b7113148f9aa4f3da6a1a9ab 579 PRINTS PR01900 YidC translocation/secretion protein signature 371 387 3.8E-16 T 22-04-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 L21SP4_RS02705 28baced8b7113148f9aa4f3da6a1a9ab 579 Pfam PF02096 60Kd inner membrane protein 386 569 3.8E-64 T 22-04-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 L21SP4_RS02705 28baced8b7113148f9aa4f3da6a1a9ab 579 TIGRFAM TIGR03593 yidC_nterm: membrane protein insertase, YidC/Oxa1 family, N-terminal domain 9 382 1.1E-29 T 22-04-2016 IPR028053 Membrane insertase YidC, N-terminal L21SP4_RS02705 28baced8b7113148f9aa4f3da6a1a9ab 579 PANTHER PTHR12428:SF14 363 573 5.1E-75 T 22-04-2016 L21SP4_RS02705 28baced8b7113148f9aa4f3da6a1a9ab 579 PANTHER PTHR12428 363 573 5.1E-75 T 22-04-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 L21SP4_RS02705 28baced8b7113148f9aa4f3da6a1a9ab 579 Pfam PF14849 YidC periplasmic domain 96 374 7.2E-22 T 22-04-2016 IPR028053 Membrane insertase YidC, N-terminal L21SP4_RS02705 28baced8b7113148f9aa4f3da6a1a9ab 579 PRINTS PR00701 60kDa inner membrane protein signature 275 290 4.3E-20 T 22-04-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 L21SP4_RS02705 28baced8b7113148f9aa4f3da6a1a9ab 579 PRINTS PR00701 60kDa inner membrane protein signature 101 122 4.3E-20 T 22-04-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 L21SP4_RS02705 28baced8b7113148f9aa4f3da6a1a9ab 579 PRINTS PR00701 60kDa inner membrane protein signature 356 376 4.3E-20 T 22-04-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 L21SP4_RS02705 28baced8b7113148f9aa4f3da6a1a9ab 579 PRINTS PR00701 60kDa inner membrane protein signature 538 561 4.3E-20 T 22-04-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 L21SP4_RS02705 28baced8b7113148f9aa4f3da6a1a9ab 579 PRINTS PR00701 60kDa inner membrane protein signature 502 524 4.3E-20 T 22-04-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 L21SP4_RS02705 28baced8b7113148f9aa4f3da6a1a9ab 579 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 385 569 5.7E-70 T 22-04-2016 IPR028055 Membrane insertase YidC/Oxa1, C-terminal L21SP4_RS10260 5c2fc03f824bfbbbe11d71d3dee65d8d 245 SUPERFAMILY SSF55174 4 88 1.7E-15 T 22-04-2016 L21SP4_RS10260 5c2fc03f824bfbbbe11d71d3dee65d8d 245 Pfam PF01479 S4 domain 4 50 9.0E-11 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 L21SP4_RS10260 5c2fc03f824bfbbbe11d71d3dee65d8d 245 PANTHER PTHR21600 5 241 4.0E-71 T 22-04-2016 L21SP4_RS10260 5c2fc03f824bfbbbe11d71d3dee65d8d 245 Gene3D G3DSA:3.10.290.10 2 59 2.5E-16 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 L21SP4_RS10260 5c2fc03f824bfbbbe11d71d3dee65d8d 245 SUPERFAMILY SSF55120 65 241 2.88E-36 T 22-04-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 L21SP4_RS10260 5c2fc03f824bfbbbe11d71d3dee65d8d 245 Pfam PF00849 RNA pseudouridylate synthase 66 206 7.7E-12 T 22-04-2016 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 L21SP4_RS10260 5c2fc03f824bfbbbe11d71d3dee65d8d 245 SMART SM00363 4 63 4.5E-8 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 L21SP4_RS10260 5c2fc03f824bfbbbe11d71d3dee65d8d 245 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 107 237 3.4E-38 T 22-04-2016 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 L21SP4_RS10260 5c2fc03f824bfbbbe11d71d3dee65d8d 245 PANTHER PTHR21600:SF25 5 241 4.0E-71 T 22-04-2016 L21SP4_RS05240 a8e1b94e57911cee0cfd4a9eff4f08b2 345 SUPERFAMILY SSF50494 43 239 1.12E-16 T 22-04-2016 IPR009003 Peptidase S1, PA clan L21SP4_RS05240 a8e1b94e57911cee0cfd4a9eff4f08b2 345 Pfam PF07589 PEP-CTERM motif 238 261 1.7E-5 T 22-04-2016 IPR013424 PEP-CTERM protein-sorting domain L21SP4_RS05240 a8e1b94e57911cee0cfd4a9eff4f08b2 345 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 239 263 1.7E-5 T 22-04-2016 IPR013424 PEP-CTERM protein-sorting domain L21SP4_RS05240 a8e1b94e57911cee0cfd4a9eff4f08b2 345 Gene3D G3DSA:2.40.10.10 93 239 1.1E-7 T 22-04-2016 L21SP4_RS05240 a8e1b94e57911cee0cfd4a9eff4f08b2 345 Pfam PF00089 Trypsin 41 235 5.3E-9 T 22-04-2016 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 L21SP4_RS05240 a8e1b94e57911cee0cfd4a9eff4f08b2 345 Gene3D G3DSA:2.40.10.10 44 92 1.4E-4 T 22-04-2016 L21SP4_RS02350 9adc159728fdd060ebdf07c70723d10d 613 Gene3D G3DSA:3.40.720.10 39 400 5.4E-62 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS02350 9adc159728fdd060ebdf07c70723d10d 613 PANTHER PTHR10342:SF199 11 398 1.5E-56 T 22-04-2016 L21SP4_RS02350 9adc159728fdd060ebdf07c70723d10d 613 PANTHER PTHR10342 11 398 1.5E-56 T 22-04-2016 L21SP4_RS02350 9adc159728fdd060ebdf07c70723d10d 613 SUPERFAMILY SSF53649 39 400 1.19E-65 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS02350 9adc159728fdd060ebdf07c70723d10d 613 Pfam PF00884 Sulfatase 39 355 6.0E-36 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS09640 2ef085aea1e4c941bf5a66c5ae2948d4 327 PANTHER PTHR34580:SF3 1 320 3.9E-62 T 22-04-2016 L21SP4_RS09640 2ef085aea1e4c941bf5a66c5ae2948d4 327 PANTHER PTHR34580 1 320 3.9E-62 T 22-04-2016 L21SP4_RS09640 2ef085aea1e4c941bf5a66c5ae2948d4 327 Gene3D G3DSA:1.10.10.10 30 72 3.0E-5 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS09640 2ef085aea1e4c941bf5a66c5ae2948d4 327 Pfam PF13280 WYL domain 151 321 4.6E-38 T 22-04-2016 IPR026881 WYL domain L21SP4_RS11390 1bb44891ed0d291a0457d9f6bbb62d8d 639 PANTHER PTHR11070:SF3 7 638 6.8E-176 T 22-04-2016 L21SP4_RS11390 1bb44891ed0d291a0457d9f6bbb62d8d 639 Pfam PF00580 UvrD/REP helicase N-terminal domain 7 273 1.8E-65 T 22-04-2016 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 L21SP4_RS11390 1bb44891ed0d291a0457d9f6bbb62d8d 639 PANTHER PTHR11070 7 638 6.8E-176 T 22-04-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 L21SP4_RS11390 1bb44891ed0d291a0457d9f6bbb62d8d 639 Gene3D G3DSA:3.40.50.300 282 389 1.1E-60 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS11390 1bb44891ed0d291a0457d9f6bbb62d8d 639 Gene3D G3DSA:3.40.50.300 545 636 1.1E-60 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS11390 1bb44891ed0d291a0457d9f6bbb62d8d 639 Gene3D G3DSA:1.10.486.10 390 531 4.4E-12 T 22-04-2016 L21SP4_RS11390 1bb44891ed0d291a0457d9f6bbb62d8d 639 Pfam PF13361 UvrD-like helicase C-terminal domain 501 606 9.5E-23 T 22-04-2016 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 L21SP4_RS11390 1bb44891ed0d291a0457d9f6bbb62d8d 639 Pfam PF13361 UvrD-like helicase C-terminal domain 279 430 4.1E-22 T 22-04-2016 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 L21SP4_RS11390 1bb44891ed0d291a0457d9f6bbb62d8d 639 Gene3D G3DSA:3.40.50.300 7 278 3.2E-78 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS11390 1bb44891ed0d291a0457d9f6bbb62d8d 639 SUPERFAMILY SSF52540 7 635 1.38E-146 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS06995 31ddd2bcfb344412619ab699828b6323 250 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 22 36 3.8E-10 T 22-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 L21SP4_RS06995 31ddd2bcfb344412619ab699828b6323 250 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 36 54 3.8E-10 T 22-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 L21SP4_RS06995 31ddd2bcfb344412619ab699828b6323 250 PANTHER PTHR30363 1 250 2.4E-79 T 22-04-2016 L21SP4_RS06995 31ddd2bcfb344412619ab699828b6323 250 SMART SM01134 71 231 5.7E-64 T 22-04-2016 L21SP4_RS06995 31ddd2bcfb344412619ab699828b6323 250 Gene3D G3DSA:1.10.10.10 7 56 1.2E-8 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS06995 31ddd2bcfb344412619ab699828b6323 250 PANTHER PTHR30363:SF1 1 250 2.4E-79 T 22-04-2016 L21SP4_RS06995 31ddd2bcfb344412619ab699828b6323 250 SMART SM00420 4 56 1.8E-16 T 22-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 L21SP4_RS06995 31ddd2bcfb344412619ab699828b6323 250 ProSitePatterns PS00894 DeoR-type HTH domain signature. 4 38 - T 22-04-2016 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 L21SP4_RS06995 31ddd2bcfb344412619ab699828b6323 250 Gene3D G3DSA:3.40.50.1360 75 211 8.1E-16 T 22-04-2016 L21SP4_RS06995 31ddd2bcfb344412619ab699828b6323 250 Pfam PF00455 DeoR C terminal sensor domain 74 230 2.1E-48 T 22-04-2016 IPR014036 DeoR C-terminal sensor domain L21SP4_RS06995 31ddd2bcfb344412619ab699828b6323 250 SUPERFAMILY SSF100950 75 230 2.2E-32 T 22-04-2016 L21SP4_RS06995 31ddd2bcfb344412619ab699828b6323 250 Pfam PF08220 DeoR-like helix-turn-helix domain 4 55 1.7E-16 T 22-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 L21SP4_RS06995 31ddd2bcfb344412619ab699828b6323 250 SUPERFAMILY SSF46785 3 75 1.4E-14 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS08100 e5045b7d74e0be5b589175a99198ef22 158 SUPERFAMILY SSF55729 9 151 6.08E-27 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase L21SP4_RS08100 e5045b7d74e0be5b589175a99198ef22 158 PANTHER PTHR23091 2 141 2.2E-20 T 22-04-2016 L21SP4_RS08100 e5045b7d74e0be5b589175a99198ef22 158 PIRSF PIRSF037663 7 156 3.4E-13 T 22-04-2016 IPR017255 Acetyltransferase, GNAT, predicted L21SP4_RS08100 e5045b7d74e0be5b589175a99198ef22 158 Gene3D G3DSA:3.40.630.30 8 153 5.1E-28 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase L21SP4_RS08100 e5045b7d74e0be5b589175a99198ef22 158 Pfam PF00583 Acetyltransferase (GNAT) family 59 141 6.9E-16 T 22-04-2016 IPR000182 GNAT domain GO:0008080 L21SP4_RS00310 0cfa73f88fdd1bce47bea5e6d2a930d1 425 SUPERFAMILY SSF50249 133 200 1.06E-14 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold L21SP4_RS00310 0cfa73f88fdd1bce47bea5e6d2a930d1 425 Gene3D G3DSA:2.40.50.140 132 199 5.2E-20 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold L21SP4_RS00310 0cfa73f88fdd1bce47bea5e6d2a930d1 425 SUPERFAMILY SSF69705 3 128 1.44E-29 T 22-04-2016 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 L21SP4_RS00310 0cfa73f88fdd1bce47bea5e6d2a930d1 425 Gene3D G3DSA:1.10.150.20 351 412 3.6E-7 T 22-04-2016 L21SP4_RS00310 0cfa73f88fdd1bce47bea5e6d2a930d1 425 SMART SM00316 135 201 4.4E-9 T 22-04-2016 IPR022967 RNA-binding domain, S1 L21SP4_RS00310 0cfa73f88fdd1bce47bea5e6d2a930d1 425 Gene3D G3DSA:3.30.300.20 279 347 1.0E-26 T 22-04-2016 IPR015946 K homology domain-like, alpha/beta L21SP4_RS00310 0cfa73f88fdd1bce47bea5e6d2a930d1 425 PANTHER PTHR22648 2 425 8.5E-132 T 22-04-2016 L21SP4_RS00310 0cfa73f88fdd1bce47bea5e6d2a930d1 425 SMART SM00322 302 366 6.6E-5 T 22-04-2016 IPR004087 K Homology domain GO:0003676 L21SP4_RS00310 0cfa73f88fdd1bce47bea5e6d2a930d1 425 SMART SM00322 231 294 30.0 T 22-04-2016 IPR004087 K Homology domain GO:0003676 L21SP4_RS00310 0cfa73f88fdd1bce47bea5e6d2a930d1 425 Pfam PF08529 NusA N-terminal domain 7 126 1.3E-30 T 22-04-2016 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 L21SP4_RS00310 0cfa73f88fdd1bce47bea5e6d2a930d1 425 SUPERFAMILY SSF54814 281 341 5.95E-14 T 22-04-2016 IPR009019 K homology domain, prokaryotic type GO:0003723 L21SP4_RS00310 0cfa73f88fdd1bce47bea5e6d2a930d1 425 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 7 343 1.1E-120 T 22-04-2016 IPR010213 Transcription termination factor NusA GO:0003723 L21SP4_RS00310 0cfa73f88fdd1bce47bea5e6d2a930d1 425 Pfam PF13184 NusA-like KH domain 231 299 4.2E-27 T 22-04-2016 IPR025249 KH domain, NusA-like GO:0003723 L21SP4_RS00310 0cfa73f88fdd1bce47bea5e6d2a930d1 425 SUPERFAMILY SSF54814 201 279 1.73E-30 T 22-04-2016 IPR009019 K homology domain, prokaryotic type GO:0003723 L21SP4_RS00310 0cfa73f88fdd1bce47bea5e6d2a930d1 425 Gene3D G3DSA:3.30.300.20 200 278 4.8E-34 T 22-04-2016 IPR015946 K homology domain-like, alpha/beta L21SP4_RS00310 0cfa73f88fdd1bce47bea5e6d2a930d1 425 SUPERFAMILY SSF47794 354 414 3.92E-6 T 22-04-2016 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 L21SP4_RS00310 0cfa73f88fdd1bce47bea5e6d2a930d1 425 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 3 420 28.389 T 22-04-2016 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 L21SP4_RS00310 0cfa73f88fdd1bce47bea5e6d2a930d1 425 Gene3D G3DSA:3.30.1480.10 4 127 4.5E-34 T 22-04-2016 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 L21SP4_RS00310 0cfa73f88fdd1bce47bea5e6d2a930d1 425 PANTHER PTHR22648:SF0 2 425 8.5E-132 T 22-04-2016 L21SP4_RS08890 e8998c6b9983c07941de7be8ad9d4123 514 PANTHER PTHR30005 1 499 1.9E-71 T 22-04-2016 L21SP4_RS08890 e8998c6b9983c07941de7be8ad9d4123 514 PANTHER PTHR30005:SF0 1 499 1.9E-71 T 22-04-2016 L21SP4_RS08890 e8998c6b9983c07941de7be8ad9d4123 514 Gene3D G3DSA:3.30.420.150 139 310 6.8E-14 T 22-04-2016 L21SP4_RS08890 e8998c6b9983c07941de7be8ad9d4123 514 SUPERFAMILY SSF53067 6 129 3.54E-24 T 22-04-2016 L21SP4_RS08890 e8998c6b9983c07941de7be8ad9d4123 514 SUPERFAMILY SSF109604 324 508 4.28E-39 T 22-04-2016 L21SP4_RS08890 e8998c6b9983c07941de7be8ad9d4123 514 SUPERFAMILY SSF53067 139 309 7.3E-17 T 22-04-2016 L21SP4_RS08890 e8998c6b9983c07941de7be8ad9d4123 514 Gene3D G3DSA:3.30.420.40 6 127 6.0E-30 T 22-04-2016 L21SP4_RS08890 e8998c6b9983c07941de7be8ad9d4123 514 Pfam PF02541 Ppx/GppA phosphatase family 26 309 1.5E-26 T 22-04-2016 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40|UniPathway: UPA00908 L21SP4_RS08890 e8998c6b9983c07941de7be8ad9d4123 514 Pfam PF01966 HD domain 339 455 3.8E-8 T 22-04-2016 IPR006674 HD domain L21SP4_RS08890 e8998c6b9983c07941de7be8ad9d4123 514 Gene3D G3DSA:1.10.3210.10 316 458 8.4E-11 T 22-04-2016 IPR006674 HD domain L21SP4_RS10145 2b5fd2c0574725089fa6d3b1bb284b4a 570 SUPERFAMILY SSF52540 7 169 1.23E-42 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS10145 2b5fd2c0574725089fa6d3b1bb284b4a 570 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 55 70 1.6E-7 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 L21SP4_RS10145 2b5fd2c0574725089fa6d3b1bb284b4a 570 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 28 46 1.6E-7 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 L21SP4_RS10145 2b5fd2c0574725089fa6d3b1bb284b4a 570 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 7 27 1.6E-7 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 L21SP4_RS10145 2b5fd2c0574725089fa6d3b1bb284b4a 570 PANTHER PTHR11649:SF37 2 147 1.2E-207 T 22-04-2016 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 L21SP4_RS10145 2b5fd2c0574725089fa6d3b1bb284b4a 570 Gene3D G3DSA:3.40.50.300 2 168 1.9E-38 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS10145 2b5fd2c0574725089fa6d3b1bb284b4a 570 Pfam PF02421 Ferrous iron transport protein B 7 159 3.5E-62 T 22-04-2016 IPR011619 Ferrous iron transport protein B, N-terminal GO:0005525|GO:0015093|GO:0015684|GO:0016021 L21SP4_RS10145 2b5fd2c0574725089fa6d3b1bb284b4a 570 PANTHER PTHR11649 265 568 1.2E-207 T 22-04-2016 L21SP4_RS10145 2b5fd2c0574725089fa6d3b1bb284b4a 570 PANTHER PTHR11649 2 147 1.2E-207 T 22-04-2016 L21SP4_RS10145 2b5fd2c0574725089fa6d3b1bb284b4a 570 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 6 155 3.8E-15 T 22-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 L21SP4_RS10145 2b5fd2c0574725089fa6d3b1bb284b4a 570 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 11 568 2.1E-158 T 22-04-2016 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 L21SP4_RS10145 2b5fd2c0574725089fa6d3b1bb284b4a 570 Pfam PF07670 Nucleoside recognition 516 567 8.1E-7 T 22-04-2016 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: REACT_15518|Reactome: REACT_1698 L21SP4_RS10145 2b5fd2c0574725089fa6d3b1bb284b4a 570 Pfam PF07670 Nucleoside recognition 355 443 1.8E-12 T 22-04-2016 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: REACT_15518|Reactome: REACT_1698 L21SP4_RS10145 2b5fd2c0574725089fa6d3b1bb284b4a 570 PANTHER PTHR11649:SF37 265 568 1.2E-207 T 22-04-2016 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 L21SP4_RS10145 2b5fd2c0574725089fa6d3b1bb284b4a 570 Pfam PF07664 Ferrous iron transport protein B C terminus 458 510 3.8E-20 T 22-04-2016 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 L21SP4_RS05495 830c69f4d4d2e775d9ac2ce7194b9665 280 PANTHER PTHR22855:SF17 5 280 4.5E-133 T 22-04-2016 L21SP4_RS05495 830c69f4d4d2e775d9ac2ce7194b9665 280 Pfam PF01039 Carboxyl transferase domain 59 239 3.4E-13 T 22-04-2016 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 L21SP4_RS05495 830c69f4d4d2e775d9ac2ce7194b9665 280 SUPERFAMILY SSF52096 24 277 9.24E-77 T 22-04-2016 IPR029045 ClpP/crotonase-like domain L21SP4_RS05495 830c69f4d4d2e775d9ac2ce7194b9665 280 PANTHER PTHR22855 5 280 4.5E-133 T 22-04-2016 L21SP4_RS05495 830c69f4d4d2e775d9ac2ce7194b9665 280 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 250 259 6.5E-36 T 22-04-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 L21SP4_RS05495 830c69f4d4d2e775d9ac2ce7194b9665 280 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 199 216 6.5E-36 T 22-04-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 L21SP4_RS05495 830c69f4d4d2e775d9ac2ce7194b9665 280 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 228 239 6.5E-36 T 22-04-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 L21SP4_RS05495 830c69f4d4d2e775d9ac2ce7194b9665 280 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 162 180 6.5E-36 T 22-04-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 L21SP4_RS05495 830c69f4d4d2e775d9ac2ce7194b9665 280 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 128 142 6.5E-36 T 22-04-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 L21SP4_RS05495 830c69f4d4d2e775d9ac2ce7194b9665 280 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 1 280 37.397 T 22-04-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 L21SP4_RS05495 830c69f4d4d2e775d9ac2ce7194b9665 280 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 4 277 2.5E-110 T 22-04-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 L21SP4_RS05495 830c69f4d4d2e775d9ac2ce7194b9665 280 Gene3D G3DSA:3.90.226.10 18 278 4.0E-67 T 22-04-2016 IPR029045 ClpP/crotonase-like domain L21SP4_RS01990 43a99eaff39bd6c832a4c2acbea5a437 601 PANTHER PTHR12631 146 424 7.2E-15 T 22-04-2016 L21SP4_RS01990 43a99eaff39bd6c832a4c2acbea5a437 601 Pfam PF01229 Glycosyl hydrolases family 39 155 331 5.1E-19 T 22-04-2016 IPR000514 Glycoside hydrolase, family 39 GO:0004553|GO:0005975 L21SP4_RS01990 43a99eaff39bd6c832a4c2acbea5a437 601 SUPERFAMILY SSF51445 157 431 6.86E-24 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily L21SP4_RS01990 43a99eaff39bd6c832a4c2acbea5a437 601 Gene3D G3DSA:3.20.20.80 120 405 7.5E-29 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP4_RS01575 75ce88879e4224bb3da2a85eaad95cf0 608 Gene3D G3DSA:1.50.10.10 287 374 3.6E-8 T 22-04-2016 IPR012341 Six-hairpin glycosidase GO:0003824 L21SP4_RS01575 75ce88879e4224bb3da2a85eaad95cf0 608 SUPERFAMILY SSF48208 468 572 2.79E-19 T 22-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP4_RS01575 75ce88879e4224bb3da2a85eaad95cf0 608 SUPERFAMILY SSF48208 280 403 2.79E-19 T 22-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP4_RS01575 75ce88879e4224bb3da2a85eaad95cf0 608 Gene3D G3DSA:1.50.10.10 375 432 6.7E-5 T 22-04-2016 IPR012341 Six-hairpin glycosidase GO:0003824 L21SP4_RS01575 75ce88879e4224bb3da2a85eaad95cf0 608 Gene3D G3DSA:1.50.10.10 490 565 6.7E-5 T 22-04-2016 IPR012341 Six-hairpin glycosidase GO:0003824 L21SP4_RS06400 13c3b3d4548acffb8fd10684ac674112 426 SUPERFAMILY SSF55874 256 424 7.99E-37 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS06400 13c3b3d4548acffb8fd10684ac674112 426 PANTHER PTHR24423 1 17 2.7E-59 T 22-04-2016 L21SP4_RS06400 13c3b3d4548acffb8fd10684ac674112 426 PANTHER PTHR24423 142 425 2.7E-59 T 22-04-2016 L21SP4_RS06400 13c3b3d4548acffb8fd10684ac674112 426 SMART SM00387 314 426 5.5E-30 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS06400 13c3b3d4548acffb8fd10684ac674112 426 Gene3D G3DSA:3.30.565.10 281 424 5.9E-38 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS06400 13c3b3d4548acffb8fd10684ac674112 426 SMART SM00065 40 193 9.7E-7 T 22-04-2016 IPR003018 GAF domain GO:0005515 L21SP4_RS06400 13c3b3d4548acffb8fd10684ac674112 426 SUPERFAMILY SSF55781 42 186 7.2E-21 T 22-04-2016 IPR029016 GAF domain-like L21SP4_RS06400 13c3b3d4548acffb8fd10684ac674112 426 Pfam PF13185 GAF domain 38 184 3.1E-15 T 22-04-2016 IPR003018 GAF domain GO:0005515 L21SP4_RS06400 13c3b3d4548acffb8fd10684ac674112 426 Gene3D G3DSA:1.10.287.130 194 262 7.0E-11 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS06400 13c3b3d4548acffb8fd10684ac674112 426 Gene3D G3DSA:3.30.450.40 23 193 2.0E-24 T 22-04-2016 IPR029016 GAF domain-like L21SP4_RS06400 13c3b3d4548acffb8fd10684ac674112 426 SUPERFAMILY SSF47384 186 267 3.92E-15 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS06400 13c3b3d4548acffb8fd10684ac674112 426 PRINTS PR00344 Bacterial sensor protein C-terminal signature 386 404 1.1E-9 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS06400 13c3b3d4548acffb8fd10684ac674112 426 PRINTS PR00344 Bacterial sensor protein C-terminal signature 410 423 1.1E-9 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS06400 13c3b3d4548acffb8fd10684ac674112 426 PRINTS PR00344 Bacterial sensor protein C-terminal signature 351 365 1.1E-9 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS06400 13c3b3d4548acffb8fd10684ac674112 426 PRINTS PR00344 Bacterial sensor protein C-terminal signature 369 379 1.1E-9 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS06400 13c3b3d4548acffb8fd10684ac674112 426 SMART SM00388 198 266 3.1E-11 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS06400 13c3b3d4548acffb8fd10684ac674112 426 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 315 424 2.4E-19 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS06400 13c3b3d4548acffb8fd10684ac674112 426 Pfam PF00512 His Kinase A (phospho-acceptor) domain 201 266 3.3E-10 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS11160 5ecb254202db9728a821f290debf5a7e 374 SUPERFAMILY SSF53383 18 363 1.39E-106 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase L21SP4_RS11160 5ecb254202db9728a821f290debf5a7e 374 Gene3D G3DSA:3.40.640.10 15 244 9.5E-80 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 L21SP4_RS11160 5ecb254202db9728a821f290debf5a7e 374 PANTHER PTHR30244:SF15 1 369 1.3E-126 T 22-04-2016 L21SP4_RS11160 5ecb254202db9728a821f290debf5a7e 374 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 18 363 5.9E-125 T 22-04-2016 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase L21SP4_RS11160 5ecb254202db9728a821f290debf5a7e 374 PANTHER PTHR30244 1 369 1.3E-126 T 22-04-2016 L21SP4_RS11160 5ecb254202db9728a821f290debf5a7e 374 Gene3D G3DSA:3.90.1150.10 246 364 1.3E-38 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 L21SP4_RS11160 5ecb254202db9728a821f290debf5a7e 374 PIRSF PIRSF000390 7 368 8.4E-108 T 22-04-2016 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase L21SP4_RS10105 dc9425385f1724c85621252f8387ba61 574 SMART SM00483 1 314 4.3E-26 T 22-04-2016 IPR002054 DNA-directed DNA polymerase X GO:0003677|GO:0003887 L21SP4_RS10105 dc9425385f1724c85621252f8387ba61 574 Pfam PF14791 DNA polymerase beta thumb 254 314 2.7E-21 T 22-04-2016 IPR029398 DNA polymerase beta, thumb domain L21SP4_RS10105 dc9425385f1724c85621252f8387ba61 574 SUPERFAMILY SSF89550 336 564 1.2E-50 T 22-04-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 L21SP4_RS10105 dc9425385f1724c85621252f8387ba61 574 Gene3D G3DSA:1.10.150.110 1 85 9.1E-25 T 22-04-2016 IPR027421 DNA polymerase family X lyase domain L21SP4_RS10105 dc9425385f1724c85621252f8387ba61 574 Pfam PF14520 Helix-hairpin-helix domain 93 147 1.7E-7 T 22-04-2016 L21SP4_RS10105 dc9425385f1724c85621252f8387ba61 574 SUPERFAMILY SSF81301 156 314 2.81E-37 T 22-04-2016 L21SP4_RS10105 dc9425385f1724c85621252f8387ba61 574 PIRSF PIRSF005047 1 569 1.9E-214 T 22-04-2016 IPR022311 Uncharacterised conserved protein UCP005047, YshC KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 L21SP4_RS10105 dc9425385f1724c85621252f8387ba61 574 Pfam PF14716 Helix-hairpin-helix domain 3 73 6.8E-23 T 22-04-2016 IPR010996 DNA polymerase beta-like, N-terminal domain L21SP4_RS10105 dc9425385f1724c85621252f8387ba61 574 PANTHER PTHR11276 3 318 3.1E-71 T 22-04-2016 L21SP4_RS10105 dc9425385f1724c85621252f8387ba61 574 SMART SM00278 127 146 250.0 T 22-04-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 L21SP4_RS10105 dc9425385f1724c85621252f8387ba61 574 SMART SM00278 52 71 1.3 T 22-04-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 L21SP4_RS10105 dc9425385f1724c85621252f8387ba61 574 SMART SM00278 92 111 0.038 T 22-04-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 L21SP4_RS10105 dc9425385f1724c85621252f8387ba61 574 Gene3D G3DSA:3.20.20.140 336 564 2.5E-47 T 22-04-2016 L21SP4_RS10105 dc9425385f1724c85621252f8387ba61 574 PRINTS PR00870 DNA-polymerase family X pol beta-like signature 184 203 2.2E-9 T 22-04-2016 IPR002008 DNA polymerase family X, beta-like GO:0003677|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 L21SP4_RS10105 dc9425385f1724c85621252f8387ba61 574 PRINTS PR00870 DNA-polymerase family X pol beta-like signature 59 76 2.2E-9 T 22-04-2016 IPR002008 DNA polymerase family X, beta-like GO:0003677|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 L21SP4_RS10105 dc9425385f1724c85621252f8387ba61 574 Pfam PF02811 PHP domain 339 420 8.0E-7 T 22-04-2016 IPR004013 PHP domain GO:0003824 L21SP4_RS10105 dc9425385f1724c85621252f8387ba61 574 Gene3D G3DSA:3.30.460.10 142 255 2.3E-12 T 22-04-2016 L21SP4_RS10105 dc9425385f1724c85621252f8387ba61 574 SUPERFAMILY SSF47802 1 85 1.02E-20 T 22-04-2016 IPR010996 DNA polymerase beta-like, N-terminal domain L21SP4_RS10105 dc9425385f1724c85621252f8387ba61 574 SMART SM00481 338 417 1.8E-13 T 22-04-2016 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 L21SP4_RS10105 dc9425385f1724c85621252f8387ba61 574 Gene3D G3DSA:3.30.210.10 256 314 1.4E-22 T 22-04-2016 IPR029398 DNA polymerase beta, thumb domain L21SP4_RS03485 da096163699b96004e15f56d69665302 240 PANTHER PTHR32552 23 226 3.9E-26 T 22-04-2016 L21SP4_RS03485 da096163699b96004e15f56d69665302 240 SUPERFAMILY SSF53098 72 236 1.9E-46 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS03485 da096163699b96004e15f56d69665302 240 Pfam PF13276 HTH-like domain 3 50 1.1E-6 T 22-04-2016 IPR025948 HTH-like domain L21SP4_RS03485 da096163699b96004e15f56d69665302 240 Gene3D G3DSA:3.30.420.10 69 224 5.5E-32 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS03485 da096163699b96004e15f56d69665302 240 Pfam PF00665 Integrase core domain 72 184 4.9E-21 T 22-04-2016 IPR001584 Integrase, catalytic core GO:0015074 L21SP4_RS04495 da096163699b96004e15f56d69665302 240 PANTHER PTHR32552 23 226 3.9E-26 T 22-04-2016 L21SP4_RS04495 da096163699b96004e15f56d69665302 240 SUPERFAMILY SSF53098 72 236 1.9E-46 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS04495 da096163699b96004e15f56d69665302 240 Pfam PF13276 HTH-like domain 3 50 1.1E-6 T 22-04-2016 IPR025948 HTH-like domain L21SP4_RS04495 da096163699b96004e15f56d69665302 240 Gene3D G3DSA:3.30.420.10 69 224 5.5E-32 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS04495 da096163699b96004e15f56d69665302 240 Pfam PF00665 Integrase core domain 72 184 4.9E-21 T 22-04-2016 IPR001584 Integrase, catalytic core GO:0015074 L21SP4_RS07535 da096163699b96004e15f56d69665302 240 PANTHER PTHR32552 23 226 3.9E-26 T 22-04-2016 L21SP4_RS07535 da096163699b96004e15f56d69665302 240 SUPERFAMILY SSF53098 72 236 1.9E-46 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS07535 da096163699b96004e15f56d69665302 240 Pfam PF13276 HTH-like domain 3 50 1.1E-6 T 22-04-2016 IPR025948 HTH-like domain L21SP4_RS07535 da096163699b96004e15f56d69665302 240 Gene3D G3DSA:3.30.420.10 69 224 5.5E-32 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS07535 da096163699b96004e15f56d69665302 240 Pfam PF00665 Integrase core domain 72 184 4.9E-21 T 22-04-2016 IPR001584 Integrase, catalytic core GO:0015074 L21SP4_RS03070 c1a63c9f6a8e7c04a24ebd97c8099985 340 Pfam PF10531 SLBB domain 225 273 1.8E-6 T 22-04-2016 IPR019554 Soluble ligand binding domain L21SP4_RS03070 c1a63c9f6a8e7c04a24ebd97c8099985 340 Pfam PF10531 SLBB domain 142 191 3.3E-7 T 22-04-2016 IPR019554 Soluble ligand binding domain L21SP4_RS03070 c1a63c9f6a8e7c04a24ebd97c8099985 340 Pfam PF02563 Polysaccharide biosynthesis/export protein 61 134 1.2E-15 T 22-04-2016 IPR003715 Polysaccharide export protein GO:0015159|GO:0015774|GO:0016020 L21SP4_RS03070 c1a63c9f6a8e7c04a24ebd97c8099985 340 Gene3D G3DSA:3.30.1950.10 69 132 2.0E-14 T 22-04-2016 L21SP4_RS03070 c1a63c9f6a8e7c04a24ebd97c8099985 340 Gene3D G3DSA:3.10.560.10 133 214 3.1E-21 T 22-04-2016 L21SP4_RS03070 c1a63c9f6a8e7c04a24ebd97c8099985 340 PANTHER PTHR33619 53 335 1.7E-45 T 22-04-2016 L21SP4_RS03070 c1a63c9f6a8e7c04a24ebd97c8099985 340 Gene3D G3DSA:3.10.560.10 215 307 6.1E-15 T 22-04-2016 L21SP4_RS03630 546428494fb3364d39c208c37d639d51 189 Gene3D G3DSA:3.40.50.1950 4 186 7.4E-44 T 22-04-2016 IPR003382 Flavoprotein GO:0003824 L21SP4_RS03630 546428494fb3364d39c208c37d639d51 189 PANTHER PTHR14359 9 184 3.8E-55 T 22-04-2016 L21SP4_RS03630 546428494fb3364d39c208c37d639d51 189 SUPERFAMILY SSF52507 7 186 3.53E-42 T 22-04-2016 IPR003382 Flavoprotein GO:0003824 L21SP4_RS03630 546428494fb3364d39c208c37d639d51 189 PANTHER PTHR14359:SF20 9 184 3.8E-55 T 22-04-2016 L21SP4_RS03630 546428494fb3364d39c208c37d639d51 189 Pfam PF02441 Flavoprotein 9 141 1.8E-22 T 22-04-2016 IPR003382 Flavoprotein GO:0003824 L21SP4_RS07135 d3b9714cd6393668ec607dc233f5b89f 268 SUPERFAMILY SSF51366 4 243 8.95E-83 T 22-04-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 L21SP4_RS07135 d3b9714cd6393668ec607dc233f5b89f 268 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 16 264 34.321 T 22-04-2016 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 L21SP4_RS07135 d3b9714cd6393668ec607dc233f5b89f 268 PANTHER PTHR10314:SF4 76 169 3.2E-17 T 22-04-2016 L21SP4_RS07135 d3b9714cd6393668ec607dc233f5b89f 268 PANTHER PTHR10314:SF4 13 53 3.2E-17 T 22-04-2016 L21SP4_RS07135 d3b9714cd6393668ec607dc233f5b89f 268 Pfam PF00290 Tryptophan synthase alpha chain 12 256 1.3E-82 T 22-04-2016 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 L21SP4_RS07135 d3b9714cd6393668ec607dc233f5b89f 268 Gene3D G3DSA:3.20.20.70 5 266 1.1E-94 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP4_RS07135 d3b9714cd6393668ec607dc233f5b89f 268 PANTHER PTHR10314 76 169 3.2E-17 T 22-04-2016 L21SP4_RS07135 d3b9714cd6393668ec607dc233f5b89f 268 PANTHER PTHR10314 13 53 3.2E-17 T 22-04-2016 L21SP4_RS07135 d3b9714cd6393668ec607dc233f5b89f 268 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 50 63 - T 22-04-2016 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 L21SP4_RS07135 d3b9714cd6393668ec607dc233f5b89f 268 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 10 261 6.7E-78 T 22-04-2016 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 L21SP4_RS06005 824b5dd73acd812c5476957766209d5e 582 PANTHER PTHR10342:SF199 387 468 9.9E-103 T 22-04-2016 L21SP4_RS06005 824b5dd73acd812c5476957766209d5e 582 PANTHER PTHR10342:SF199 4 365 9.9E-103 T 22-04-2016 L21SP4_RS06005 824b5dd73acd812c5476957766209d5e 582 Gene3D G3DSA:3.40.720.10 24 350 2.0E-84 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS06005 824b5dd73acd812c5476957766209d5e 582 Pfam PF00884 Sulfatase 26 326 2.4E-62 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS06005 824b5dd73acd812c5476957766209d5e 582 Gene3D G3DSA:3.30.1120.10 381 447 3.8E-7 T 22-04-2016 L21SP4_RS06005 824b5dd73acd812c5476957766209d5e 582 SUPERFAMILY SSF53649 24 439 1.6E-101 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS06005 824b5dd73acd812c5476957766209d5e 582 PANTHER PTHR10342 387 468 9.9E-103 T 22-04-2016 L21SP4_RS06005 824b5dd73acd812c5476957766209d5e 582 PANTHER PTHR10342 4 365 9.9E-103 T 22-04-2016 L21SP4_RS00635 c2bbd850e73be61f05401d11bc36bfb2 431 PIRSF PIRSF000534 5 431 1.6E-157 T 22-04-2016 IPR012004 Pyrophosphate-dependent phosphofructokinase TP0108-type GO:0003872|GO:0005524|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|UniPathway: UPA00109 L21SP4_RS00635 c2bbd850e73be61f05401d11bc36bfb2 431 PANTHER PTHR13697 55 424 1.2E-158 T 22-04-2016 L21SP4_RS00635 c2bbd850e73be61f05401d11bc36bfb2 431 Pfam PF00365 Phosphofructokinase 71 376 2.8E-62 T 22-04-2016 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 L21SP4_RS00635 c2bbd850e73be61f05401d11bc36bfb2 431 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 160 176 8.7E-22 T 22-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 L21SP4_RS00635 c2bbd850e73be61f05401d11bc36bfb2 431 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 211 229 8.7E-22 T 22-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 L21SP4_RS00635 c2bbd850e73be61f05401d11bc36bfb2 431 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 289 301 8.7E-22 T 22-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 L21SP4_RS00635 c2bbd850e73be61f05401d11bc36bfb2 431 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 232 248 8.7E-22 T 22-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 L21SP4_RS00635 c2bbd850e73be61f05401d11bc36bfb2 431 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 73 92 8.7E-22 T 22-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 L21SP4_RS00635 c2bbd850e73be61f05401d11bc36bfb2 431 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 193 210 8.7E-22 T 22-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 L21SP4_RS00635 c2bbd850e73be61f05401d11bc36bfb2 431 SUPERFAMILY SSF53784 53 425 2.62E-114 T 22-04-2016 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 L21SP4_RS00635 c2bbd850e73be61f05401d11bc36bfb2 431 Gene3D G3DSA:3.40.50.450 53 289 1.5E-70 T 22-04-2016 L21SP4_RS00635 c2bbd850e73be61f05401d11bc36bfb2 431 PANTHER PTHR13697:SF27 55 424 1.2E-158 T 22-04-2016 L21SP4_RS09330 662a482bfd04e7dde99ee41a51e68eb5 463 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 9 463 31.217 T 22-04-2016 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 L21SP4_RS09330 662a482bfd04e7dde99ee41a51e68eb5 463 Gene3D G3DSA:3.30.1360.120 7 132 3.0E-38 T 22-04-2016 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 L21SP4_RS09330 662a482bfd04e7dde99ee41a51e68eb5 463 Pfam PF01926 50S ribosome-binding GTPase 229 342 1.0E-21 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 L21SP4_RS09330 662a482bfd04e7dde99ee41a51e68eb5 463 Gene3D G3DSA:1.20.120.430 259 282 4.5E-46 T 22-04-2016 IPR027368 tRNA modification GTPase MnmE domain 2 L21SP4_RS09330 662a482bfd04e7dde99ee41a51e68eb5 463 Gene3D G3DSA:1.20.120.430 391 463 4.5E-46 T 22-04-2016 IPR027368 tRNA modification GTPase MnmE domain 2 L21SP4_RS09330 662a482bfd04e7dde99ee41a51e68eb5 463 Gene3D G3DSA:1.20.120.430 133 193 4.5E-46 T 22-04-2016 IPR027368 tRNA modification GTPase MnmE domain 2 L21SP4_RS09330 662a482bfd04e7dde99ee41a51e68eb5 463 Gene3D G3DSA:3.40.50.300 227 258 1.1E-6 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS09330 662a482bfd04e7dde99ee41a51e68eb5 463 PANTHER PTHR11649 12 463 9.8E-138 T 22-04-2016 L21SP4_RS09330 662a482bfd04e7dde99ee41a51e68eb5 463 SUPERFAMILY SSF52540 83 163 4.73E-38 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS09330 662a482bfd04e7dde99ee41a51e68eb5 463 SUPERFAMILY SSF52540 199 377 4.73E-38 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS09330 662a482bfd04e7dde99ee41a51e68eb5 463 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 15 463 1.0E-97 T 22-04-2016 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 L21SP4_RS09330 662a482bfd04e7dde99ee41a51e68eb5 463 Pfam PF10396 GTP-binding protein TrmE N-terminus 10 131 8.3E-36 T 22-04-2016 IPR018948 GTP-binding protein TrmE, N-terminal L21SP4_RS09330 662a482bfd04e7dde99ee41a51e68eb5 463 Pfam PF12631 MnmE helical domain 134 460 2.1E-47 T 22-04-2016 IPR025867 MnmE, helical domain L21SP4_RS09330 662a482bfd04e7dde99ee41a51e68eb5 463 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 228 373 4.1E-22 T 22-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 L21SP4_RS09330 662a482bfd04e7dde99ee41a51e68eb5 463 PANTHER PTHR11649:SF56 12 463 9.8E-138 T 22-04-2016 L21SP4_RS09330 662a482bfd04e7dde99ee41a51e68eb5 463 Gene3D G3DSA:3.40.50.300 297 383 4.8E-6 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS03625 83a7b239ae94f74543bca24f6605232c 215 Gene3D G3DSA:3.40.50.10300 4 209 3.5E-53 T 22-04-2016 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|UniPathway: UPA00241 L21SP4_RS03625 83a7b239ae94f74543bca24f6605232c 215 SUPERFAMILY SSF102645 4 209 3.79E-50 T 22-04-2016 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|UniPathway: UPA00241 L21SP4_RS03625 83a7b239ae94f74543bca24f6605232c 215 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 4 170 3.0E-49 T 22-04-2016 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|UniPathway: UPA00241 L21SP4_RS03625 83a7b239ae94f74543bca24f6605232c 215 PANTHER PTHR14359:SF20 4 208 1.7E-55 T 22-04-2016 L21SP4_RS03625 83a7b239ae94f74543bca24f6605232c 215 PANTHER PTHR14359 4 208 1.7E-55 T 22-04-2016 L21SP4_RS01320 729a723bf6434f4afeac766514a336e2 569 Pfam PF00437 Type II/IV secretion system protein 193 459 2.9E-79 T 22-04-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 L21SP4_RS01320 729a723bf6434f4afeac766514a336e2 569 SMART SM00382 320 554 1.2E-4 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS01320 729a723bf6434f4afeac766514a336e2 569 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 387 401 - T 22-04-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 L21SP4_RS01320 729a723bf6434f4afeac766514a336e2 569 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 41 145 5.6E-19 T 22-04-2016 IPR007831 General secretory system II, protein E, N-terminal GO:0005524|GO:0006810 L21SP4_RS01320 729a723bf6434f4afeac766514a336e2 569 PANTHER PTHR30258 1 569 5.6E-205 T 22-04-2016 L21SP4_RS01320 729a723bf6434f4afeac766514a336e2 569 SUPERFAMILY SSF52540 172 567 5.16E-98 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS01320 729a723bf6434f4afeac766514a336e2 569 PANTHER PTHR30258:SF1 1 569 5.6E-205 T 22-04-2016 L21SP4_RS01320 729a723bf6434f4afeac766514a336e2 569 SUPERFAMILY SSF160246 5 140 2.62E-27 T 22-04-2016 L21SP4_RS01320 729a723bf6434f4afeac766514a336e2 569 Gene3D G3DSA:3.40.50.300 298 567 1.4E-92 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS01320 729a723bf6434f4afeac766514a336e2 569 Gene3D G3DSA:3.30.450.90 166 292 6.5E-51 T 22-04-2016 L21SP4_RS08770 aa2f1e1d43e38d0f2bb3603c0be1c5d5 258 Pfam PF02565 Recombination protein O C terminal 91 240 6.3E-21 T 22-04-2016 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 L21SP4_RS08770 aa2f1e1d43e38d0f2bb3603c0be1c5d5 258 Gene3D G3DSA:2.40.50.140 3 82 4.0E-8 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold L21SP4_RS08770 aa2f1e1d43e38d0f2bb3603c0be1c5d5 258 Pfam PF11967 Recombination protein O N terminal 1 77 1.8E-10 T 22-04-2016 IPR022572 DNA replication/recombination mediator RecO, N-terminal L21SP4_RS08770 aa2f1e1d43e38d0f2bb3603c0be1c5d5 258 SUPERFAMILY SSF57863 83 239 1.12E-20 T 22-04-2016 L21SP4_RS08770 aa2f1e1d43e38d0f2bb3603c0be1c5d5 258 PANTHER PTHR33991 1 240 3.1E-29 T 22-04-2016 L21SP4_RS08770 aa2f1e1d43e38d0f2bb3603c0be1c5d5 258 SUPERFAMILY SSF50249 1 76 6.68E-9 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold L21SP4_RS08770 aa2f1e1d43e38d0f2bb3603c0be1c5d5 258 Hamap MF_00201 DNA repair protein RecO [recO]. 1 252 19.291 T 22-04-2016 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 L21SP4_RS08770 aa2f1e1d43e38d0f2bb3603c0be1c5d5 258 TIGRFAM TIGR00613 reco: DNA repair protein RecO 6 201 8.8E-22 T 22-04-2016 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 L21SP4_RS06680 170a347cb743c5d8dec6ffd6bf7b8f49 485 Gene3D G3DSA:3.30.1120.10 336 361 5.0E-17 T 22-04-2016 L21SP4_RS06680 170a347cb743c5d8dec6ffd6bf7b8f49 485 Gene3D G3DSA:3.30.1120.10 403 449 5.0E-17 T 22-04-2016 L21SP4_RS06680 170a347cb743c5d8dec6ffd6bf7b8f49 485 Pfam PF00884 Sulfatase 7 292 7.2E-41 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS06680 170a347cb743c5d8dec6ffd6bf7b8f49 485 PANTHER PTHR10342 2 449 5.0E-71 T 22-04-2016 L21SP4_RS06680 170a347cb743c5d8dec6ffd6bf7b8f49 485 PANTHER PTHR10342:SF218 2 449 5.0E-71 T 22-04-2016 L21SP4_RS06680 170a347cb743c5d8dec6ffd6bf7b8f49 485 SUPERFAMILY SSF53649 401 447 1.6E-89 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS06680 170a347cb743c5d8dec6ffd6bf7b8f49 485 SUPERFAMILY SSF53649 5 359 1.6E-89 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS06680 170a347cb743c5d8dec6ffd6bf7b8f49 485 Gene3D G3DSA:3.40.720.10 4 310 5.1E-66 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS06415 347f7e0da58fba79bcc2c5b2d8443d57 131 Gene3D G3DSA:3.40.30.10 5 53 6.3E-4 T 22-04-2016 IPR012336 Thioredoxin-like fold L21SP4_RS07155 833b8e579010a14af663d3aab8f64640 209 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 200 1.0E-61 T 22-04-2016 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 L21SP4_RS07155 833b8e579010a14af663d3aab8f64640 209 PANTHER PTHR11670:SF27 1 209 3.3E-77 T 22-04-2016 L21SP4_RS07155 833b8e579010a14af663d3aab8f64640 209 Gene3D G3DSA:3.20.19.10 3 204 1.4E-38 T 22-04-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel L21SP4_RS07155 833b8e579010a14af663d3aab8f64640 209 SUPERFAMILY SSF52016 1 204 4.71E-49 T 22-04-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel L21SP4_RS07155 833b8e579010a14af663d3aab8f64640 209 Pfam PF00694 Aconitase C-terminal domain 1 132 5.4E-27 T 22-04-2016 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 L21SP4_RS07155 833b8e579010a14af663d3aab8f64640 209 PANTHER PTHR11670 1 209 3.3E-77 T 22-04-2016 IPR015937 Aconitase/isopropylmalate dehydratase GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 L21SP4_RS07155 833b8e579010a14af663d3aab8f64640 209 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 208 33.658 T 22-04-2016 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 L21SP4_RS11050 651269503b1a5348695b3f8360505110 181 Gene3D G3DSA:3.10.350.10 136 181 7.3E-19 T 22-04-2016 IPR018392 LysM domain L21SP4_RS11050 651269503b1a5348695b3f8360505110 181 Pfam PF01476 LysM domain 137 180 6.4E-17 T 22-04-2016 IPR018392 LysM domain L21SP4_RS11050 651269503b1a5348695b3f8360505110 181 SMART SM00257 136 180 2.4E-18 T 22-04-2016 IPR018392 LysM domain L21SP4_RS11050 651269503b1a5348695b3f8360505110 181 SUPERFAMILY SSF54106 136 180 1.44E-12 T 22-04-2016 IPR018392 LysM domain L21SP4_RS11035 49690ff83b5c3e5562c04b1e9e638869 524 Pfam PF00884 Sulfatase 33 401 2.4E-72 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS11035 49690ff83b5c3e5562c04b1e9e638869 524 PANTHER PTHR10342 346 513 2.5E-142 T 22-04-2016 L21SP4_RS11035 49690ff83b5c3e5562c04b1e9e638869 524 PANTHER PTHR10342 260 314 2.5E-142 T 22-04-2016 L21SP4_RS11035 49690ff83b5c3e5562c04b1e9e638869 524 PANTHER PTHR10342 8 233 2.5E-142 T 22-04-2016 L21SP4_RS11035 49690ff83b5c3e5562c04b1e9e638869 524 Gene3D G3DSA:3.40.720.10 31 422 3.0E-112 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS11035 49690ff83b5c3e5562c04b1e9e638869 524 SUPERFAMILY SSF53649 32 491 4.36E-130 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS11035 49690ff83b5c3e5562c04b1e9e638869 524 PANTHER PTHR10342:SF199 346 513 2.5E-142 T 22-04-2016 L21SP4_RS11035 49690ff83b5c3e5562c04b1e9e638869 524 PANTHER PTHR10342:SF199 260 314 2.5E-142 T 22-04-2016 L21SP4_RS11035 49690ff83b5c3e5562c04b1e9e638869 524 PANTHER PTHR10342:SF199 8 233 2.5E-142 T 22-04-2016 L21SP4_RS11035 49690ff83b5c3e5562c04b1e9e638869 524 ProSitePatterns PS00149 Sulfatases signature 2. 115 125 - T 22-04-2016 IPR024607 Sulfatase, conserved site L21SP4_RS11035 49690ff83b5c3e5562c04b1e9e638869 524 Gene3D G3DSA:3.30.1120.10 432 498 1.9E-13 T 22-04-2016 L21SP4_RS02485 ae6d1ba9195396a6c908251a7ae5d940 406 Gene3D G3DSA:3.10.290.10 331 400 1.1E-26 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 L21SP4_RS02485 ae6d1ba9195396a6c908251a7ae5d940 406 SUPERFAMILY SSF55174 302 400 3.14E-21 T 22-04-2016 L21SP4_RS02485 ae6d1ba9195396a6c908251a7ae5d940 406 Gene3D G3DSA:3.40.50.620 8 231 1.3E-78 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP4_RS02485 ae6d1ba9195396a6c908251a7ae5d940 406 Gene3D G3DSA:1.10.240.10 232 330 3.5E-32 T 22-04-2016 L21SP4_RS02485 ae6d1ba9195396a6c908251a7ae5d940 406 PANTHER PTHR11766:SF1 23 406 1.4E-208 T 22-04-2016 L21SP4_RS02485 ae6d1ba9195396a6c908251a7ae5d940 406 Pfam PF00579 tRNA synthetases class I (W and Y) 35 321 6.7E-73 T 22-04-2016 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 L21SP4_RS02485 ae6d1ba9195396a6c908251a7ae5d940 406 Pfam PF01479 S4 domain 344 385 1.2E-10 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 L21SP4_RS02485 ae6d1ba9195396a6c908251a7ae5d940 406 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 46 56 - T 22-04-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 L21SP4_RS02485 ae6d1ba9195396a6c908251a7ae5d940 406 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 165 180 2.4E-25 T 22-04-2016 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1|Reactome: REACT_71 L21SP4_RS02485 ae6d1ba9195396a6c908251a7ae5d940 406 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 215 227 2.4E-25 T 22-04-2016 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1|Reactome: REACT_71 L21SP4_RS02485 ae6d1ba9195396a6c908251a7ae5d940 406 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 182 204 2.4E-25 T 22-04-2016 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1|Reactome: REACT_71 L21SP4_RS02485 ae6d1ba9195396a6c908251a7ae5d940 406 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 50 72 2.4E-25 T 22-04-2016 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1|Reactome: REACT_71 L21SP4_RS02485 ae6d1ba9195396a6c908251a7ae5d940 406 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 8 401 9.7E-118 T 22-04-2016 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1|Reactome: REACT_71 L21SP4_RS02485 ae6d1ba9195396a6c908251a7ae5d940 406 SMART SM00363 341 400 2.3E-6 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 L21SP4_RS02485 ae6d1ba9195396a6c908251a7ae5d940 406 Hamap MF_02007 Tyrosine--tRNA ligase [tyrS]. 2 401 46.061 T 22-04-2016 IPR024108 Tyrosine-tRNA ligase, bacterial-type, type 2 GO:0004831 KEGG: 00970+6.1.1.1 L21SP4_RS02485 ae6d1ba9195396a6c908251a7ae5d940 406 PANTHER PTHR11766 23 406 1.4E-208 T 22-04-2016 IPR024088 Tyrosine-tRNA ligase, bacterial-type GO:0004831 KEGG: 00970+6.1.1.1 L21SP4_RS02485 ae6d1ba9195396a6c908251a7ae5d940 406 SUPERFAMILY SSF52374 26 320 1.37E-87 T 22-04-2016 L21SP4_RS06220 4ef7154b3d09a6f288dd392802f7e19c 149 Pfam PF02643 Uncharacterized ACR, COG1430 37 138 5.5E-29 T 22-04-2016 IPR003795 Protein of unknown function DUF192 L21SP4_RS06220 4ef7154b3d09a6f288dd392802f7e19c 149 PANTHER PTHR37953 25 147 8.4E-27 T 22-04-2016 L21SP4_RS06220 4ef7154b3d09a6f288dd392802f7e19c 149 PANTHER PTHR37953:SF1 25 147 8.4E-27 T 22-04-2016 L21SP4_RS02320 ee949464a01af0cc31b6088ff2478841 112 SUPERFAMILY SSF52091 1 109 1.59E-22 T 22-04-2016 IPR002645 STAS domain L21SP4_RS02320 ee949464a01af0cc31b6088ff2478841 112 PANTHER PTHR33495 1 112 1.5E-15 T 22-04-2016 L21SP4_RS02320 ee949464a01af0cc31b6088ff2478841 112 Gene3D G3DSA:3.30.750.24 1 111 1.1E-24 T 22-04-2016 IPR002645 STAS domain L21SP4_RS02320 ee949464a01af0cc31b6088ff2478841 112 Pfam PF01740 STAS domain 3 107 1.6E-13 T 22-04-2016 IPR002645 STAS domain L21SP4_RS02320 ee949464a01af0cc31b6088ff2478841 112 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 1 104 1.2E-16 T 22-04-2016 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 L21SP4_RS04795 9d9aab3c70a274eecf628eb79dc3b3cc 430 Gene3D G3DSA:3.40.640.10 7 291 2.1E-116 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 L21SP4_RS04795 9d9aab3c70a274eecf628eb79dc3b3cc 430 Gene3D G3DSA:3.90.1150.10 293 429 2.6E-49 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 L21SP4_RS04795 9d9aab3c70a274eecf628eb79dc3b3cc 430 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 9 427 1.4E-135 T 22-04-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 L21SP4_RS04795 9d9aab3c70a274eecf628eb79dc3b3cc 430 PANTHER PTHR11808 270 430 6.2E-229 T 22-04-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 L21SP4_RS04795 9d9aab3c70a274eecf628eb79dc3b3cc 430 PANTHER PTHR11808 1 237 6.2E-229 T 22-04-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 L21SP4_RS04795 9d9aab3c70a274eecf628eb79dc3b3cc 430 SUPERFAMILY SSF53383 7 427 7.85E-128 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase L21SP4_RS04795 9d9aab3c70a274eecf628eb79dc3b3cc 430 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 201 215 - T 22-04-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 L21SP4_RS04795 9d9aab3c70a274eecf628eb79dc3b3cc 430 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 8 427 1.7E-182 T 22-04-2016 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 KEGG: 00270+2.5.1.49|MetaCyc: PWY-5344|MetaCyc: PWY-7174 L21SP4_RS04795 9d9aab3c70a274eecf628eb79dc3b3cc 430 PIRSF PIRSF001434 1 430 5.1E-131 T 22-04-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 L21SP4_RS04795 9d9aab3c70a274eecf628eb79dc3b3cc 430 PANTHER PTHR11808:SF12 270 430 6.2E-229 T 22-04-2016 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 KEGG: 00270+2.5.1.49|MetaCyc: PWY-5344|MetaCyc: PWY-7174 L21SP4_RS04795 9d9aab3c70a274eecf628eb79dc3b3cc 430 PANTHER PTHR11808:SF12 1 237 6.2E-229 T 22-04-2016 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 KEGG: 00270+2.5.1.49|MetaCyc: PWY-5344|MetaCyc: PWY-7174 L21SP4_RS02580 3eaa0a69c76b5e9484cad6ad799c033b 528 PANTHER PTHR11451 185 379 1.1E-67 T 22-04-2016 L21SP4_RS02580 3eaa0a69c76b5e9484cad6ad799c033b 528 PANTHER PTHR11451 3 135 1.1E-67 T 22-04-2016 L21SP4_RS02580 3eaa0a69c76b5e9484cad6ad799c033b 528 PRINTS PR00987 Glutamyl-tRNA synthetase signature 35 48 4.1E-14 T 22-04-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 L21SP4_RS02580 3eaa0a69c76b5e9484cad6ad799c033b 528 PRINTS PR00987 Glutamyl-tRNA synthetase signature 6 18 4.1E-14 T 22-04-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 L21SP4_RS02580 3eaa0a69c76b5e9484cad6ad799c033b 528 PRINTS PR00987 Glutamyl-tRNA synthetase signature 20 31 4.1E-14 T 22-04-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 L21SP4_RS02580 3eaa0a69c76b5e9484cad6ad799c033b 528 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 9 20 - T 22-04-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 L21SP4_RS02580 3eaa0a69c76b5e9484cad6ad799c033b 528 Gene3D G3DSA:3.90.800.10 200 239 5.2E-5 T 22-04-2016 L21SP4_RS02580 3eaa0a69c76b5e9484cad6ad799c033b 528 Gene3D G3DSA:3.90.800.10 68 97 6.0E-5 T 22-04-2016 L21SP4_RS02580 3eaa0a69c76b5e9484cad6ad799c033b 528 Gene3D G3DSA:1.10.1160.10 293 374 2.0E-29 T 22-04-2016 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: REACT_71 L21SP4_RS02580 3eaa0a69c76b5e9484cad6ad799c033b 528 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 195 366 1.0E-36 T 22-04-2016 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 Reactome: REACT_71 L21SP4_RS02580 3eaa0a69c76b5e9484cad6ad799c033b 528 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 3 98 6.3E-32 T 22-04-2016 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 Reactome: REACT_71 L21SP4_RS02580 3eaa0a69c76b5e9484cad6ad799c033b 528 Gene3D G3DSA:3.40.50.620 2 67 1.8E-44 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP4_RS02580 3eaa0a69c76b5e9484cad6ad799c033b 528 Gene3D G3DSA:3.40.50.620 241 290 1.8E-44 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP4_RS02580 3eaa0a69c76b5e9484cad6ad799c033b 528 Gene3D G3DSA:1.10.10.350 424 522 1.4E-25 T 22-04-2016 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 L21SP4_RS02580 3eaa0a69c76b5e9484cad6ad799c033b 528 PANTHER PTHR11451:SF41 185 379 1.1E-67 T 22-04-2016 L21SP4_RS02580 3eaa0a69c76b5e9484cad6ad799c033b 528 PANTHER PTHR11451:SF41 3 135 1.1E-67 T 22-04-2016 L21SP4_RS02580 3eaa0a69c76b5e9484cad6ad799c033b 528 SUPERFAMILY SSF48163 360 522 3.92E-41 T 22-04-2016 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 L21SP4_RS02580 3eaa0a69c76b5e9484cad6ad799c033b 528 Hamap MF_00022_B Glutamate--tRNA ligase [gltX]. 3 523 28.735 T 22-04-2016 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 L21SP4_RS02580 3eaa0a69c76b5e9484cad6ad799c033b 528 SUPERFAMILY SSF52374 3 146 6.86E-64 T 22-04-2016 L21SP4_RS02580 3eaa0a69c76b5e9484cad6ad799c033b 528 SUPERFAMILY SSF52374 202 373 6.86E-64 T 22-04-2016 L21SP4_RS02580 3eaa0a69c76b5e9484cad6ad799c033b 528 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 206 520 2.4E-89 T 22-04-2016 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 L21SP4_RS02205 785956fbf06ead920a7d22791f087362 345 PANTHER PTHR11405 11 338 9.5E-86 T 22-04-2016 L21SP4_RS02205 785956fbf06ead920a7d22791f087362 345 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 43 327 4.1E-74 T 22-04-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 L21SP4_RS02205 785956fbf06ead920a7d22791f087362 345 Gene3D G3DSA:3.40.50.1370 18 161 4.4E-34 T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 L21SP4_RS02205 785956fbf06ead920a7d22791f087362 345 Gene3D G3DSA:3.40.50.1370 162 316 2.8E-46 T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 L21SP4_RS02205 785956fbf06ead920a7d22791f087362 345 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 294 317 3.7E-20 T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 L21SP4_RS02205 785956fbf06ead920a7d22791f087362 345 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 284 293 3.7E-20 T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 L21SP4_RS02205 785956fbf06ead920a7d22791f087362 345 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 155 166 3.7E-20 T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 L21SP4_RS02205 785956fbf06ead920a7d22791f087362 345 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 66 85 3.7E-20 T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 L21SP4_RS02205 785956fbf06ead920a7d22791f087362 345 PANTHER PTHR11405:SF16 11 338 9.5E-86 T 22-04-2016 L21SP4_RS02205 785956fbf06ead920a7d22791f087362 345 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 177 327 2.2E-25 T 22-04-2016 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 L21SP4_RS02205 785956fbf06ead920a7d22791f087362 345 PRINTS PR00101 Aspartate carbamoyltransferase signature 310 324 3.6E-25 T 22-04-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 L21SP4_RS02205 785956fbf06ead920a7d22791f087362 345 PRINTS PR00101 Aspartate carbamoyltransferase signature 56 78 3.6E-25 T 22-04-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 L21SP4_RS02205 785956fbf06ead920a7d22791f087362 345 PRINTS PR00101 Aspartate carbamoyltransferase signature 154 171 3.6E-25 T 22-04-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 L21SP4_RS02205 785956fbf06ead920a7d22791f087362 345 PRINTS PR00101 Aspartate carbamoyltransferase signature 288 293 3.6E-25 T 22-04-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 L21SP4_RS02205 785956fbf06ead920a7d22791f087362 345 PRINTS PR00101 Aspartate carbamoyltransferase signature 95 104 3.6E-25 T 22-04-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 L21SP4_RS02205 785956fbf06ead920a7d22791f087362 345 PRINTS PR00101 Aspartate carbamoyltransferase signature 249 258 3.6E-25 T 22-04-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 L21SP4_RS02205 785956fbf06ead920a7d22791f087362 345 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 19 167 2.0E-30 T 22-04-2016 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 L21SP4_RS02205 785956fbf06ead920a7d22791f087362 345 SUPERFAMILY SSF53671 18 330 7.33E-75 T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 L21SP4_RS10560 fcc4f6265215cc9cdbb14b23b12806f6 293 Gene3D G3DSA:3.40.190.10 36 119 2.5E-27 T 22-04-2016 L21SP4_RS10560 fcc4f6265215cc9cdbb14b23b12806f6 293 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 37 281 3.7E-65 T 22-04-2016 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 L21SP4_RS10560 fcc4f6265215cc9cdbb14b23b12806f6 293 PANTHER PTHR30177 8 286 4.1E-80 T 22-04-2016 L21SP4_RS10560 fcc4f6265215cc9cdbb14b23b12806f6 293 SUPERFAMILY SSF53850 35 293 1.17E-78 T 22-04-2016 L21SP4_RS10560 fcc4f6265215cc9cdbb14b23b12806f6 293 PANTHER PTHR30177:SF0 8 286 4.1E-80 T 22-04-2016 L21SP4_RS10560 fcc4f6265215cc9cdbb14b23b12806f6 293 Gene3D G3DSA:3.40.190.100 121 242 7.3E-38 T 22-04-2016 L21SP4_RS01450 707c269e47ba4bb9136e09cb0650dffa 407 SUPERFAMILY SSF53383 37 394 2.72E-79 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase L21SP4_RS01450 707c269e47ba4bb9136e09cb0650dffa 407 Gene3D G3DSA:3.40.640.10 61 285 8.3E-56 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 L21SP4_RS01450 707c269e47ba4bb9136e09cb0650dffa 407 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 246 259 - T 22-04-2016 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 Reactome: REACT_13 L21SP4_RS01450 707c269e47ba4bb9136e09cb0650dffa 407 Gene3D G3DSA:3.90.1150.10 286 370 8.1E-11 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 L21SP4_RS01450 707c269e47ba4bb9136e09cb0650dffa 407 PANTHER PTHR11751:SF429 25 378 9.4E-97 T 22-04-2016 L21SP4_RS01450 707c269e47ba4bb9136e09cb0650dffa 407 Pfam PF00155 Aminotransferase class I and II 44 371 8.3E-41 T 22-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 L21SP4_RS01450 707c269e47ba4bb9136e09cb0650dffa 407 PANTHER PTHR11751 25 378 9.4E-97 T 22-04-2016 L21SP4_RS02995 30bfd9dd3d1f4959fd02649dc4e1ebbd 377 Pfam PF00534 Glycosyl transferases group 1 189 353 5.6E-36 T 22-04-2016 IPR001296 Glycosyl transferase, family 1 L21SP4_RS02995 30bfd9dd3d1f4959fd02649dc4e1ebbd 377 PANTHER PTHR12526 1 377 2.5E-67 T 22-04-2016 L21SP4_RS02995 30bfd9dd3d1f4959fd02649dc4e1ebbd 377 Gene3D G3DSA:3.40.50.2000 166 352 6.7E-33 T 22-04-2016 L21SP4_RS02995 30bfd9dd3d1f4959fd02649dc4e1ebbd 377 Pfam PF13579 Glycosyl transferase 4-like domain 17 174 2.5E-24 T 22-04-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain L21SP4_RS02995 30bfd9dd3d1f4959fd02649dc4e1ebbd 377 SUPERFAMILY SSF53756 7 373 1.98E-86 T 22-04-2016 L21SP4_RS10330 3b6010a5153eea3b45d7c471a866636b 819 PANTHER PTHR11638:SF18 169 817 0.0 T 22-04-2016 L21SP4_RS10330 3b6010a5153eea3b45d7c471a866636b 819 PANTHER PTHR11638:SF18 1 139 0.0 T 22-04-2016 L21SP4_RS10330 3b6010a5153eea3b45d7c471a866636b 819 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 15 67 2.1E-14 T 22-04-2016 IPR004176 Clp, N-terminal GO:0019538 L21SP4_RS10330 3b6010a5153eea3b45d7c471a866636b 819 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 92 142 4.3E-17 T 22-04-2016 IPR004176 Clp, N-terminal GO:0019538 L21SP4_RS10330 3b6010a5153eea3b45d7c471a866636b 819 PANTHER PTHR11638 169 817 0.0 T 22-04-2016 L21SP4_RS10330 3b6010a5153eea3b45d7c471a866636b 819 PANTHER PTHR11638 1 139 0.0 T 22-04-2016 L21SP4_RS10330 3b6010a5153eea3b45d7c471a866636b 819 Pfam PF02151 UvrB/uvrC motif 430 462 9.9E-7 T 22-04-2016 IPR001943 UVR domain GO:0005515 L21SP4_RS10330 3b6010a5153eea3b45d7c471a866636b 819 SUPERFAMILY SSF81923 2 133 2.9E-31 T 22-04-2016 IPR004176 Clp, N-terminal GO:0019538 L21SP4_RS10330 3b6010a5153eea3b45d7c471a866636b 819 SMART SM00382 549 727 1.5E-10 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS10330 3b6010a5153eea3b45d7c471a866636b 819 SMART SM00382 212 357 3.5E-10 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS10330 3b6010a5153eea3b45d7c471a866636b 819 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 553 571 1.1E-39 T 22-04-2016 IPR001270 ClpA/B family GO:0005524 L21SP4_RS10330 3b6010a5153eea3b45d7c471a866636b 819 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 627 645 1.1E-39 T 22-04-2016 IPR001270 ClpA/B family GO:0005524 L21SP4_RS10330 3b6010a5153eea3b45d7c471a866636b 819 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 598 616 1.1E-39 T 22-04-2016 IPR001270 ClpA/B family GO:0005524 L21SP4_RS10330 3b6010a5153eea3b45d7c471a866636b 819 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 660 674 1.1E-39 T 22-04-2016 IPR001270 ClpA/B family GO:0005524 L21SP4_RS10330 3b6010a5153eea3b45d7c471a866636b 819 Gene3D G3DSA:3.40.50.300 175 355 1.3E-44 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS10330 3b6010a5153eea3b45d7c471a866636b 819 Gene3D G3DSA:1.10.8.60 357 440 2.9E-33 T 22-04-2016 L21SP4_RS10330 3b6010a5153eea3b45d7c471a866636b 819 SMART SM01086 726 815 5.8E-28 T 22-04-2016 IPR019489 Clp ATPase, C-terminal L21SP4_RS10330 3b6010a5153eea3b45d7c471a866636b 819 SUPERFAMILY SSF52540 498 805 6.81E-72 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS10330 3b6010a5153eea3b45d7c471a866636b 819 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 726 805 4.1E-23 T 22-04-2016 IPR019489 Clp ATPase, C-terminal L21SP4_RS10330 3b6010a5153eea3b45d7c471a866636b 819 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 307 319 - T 22-04-2016 IPR018368 ClpA/B, conserved site 1 GO:0005524 L21SP4_RS10330 3b6010a5153eea3b45d7c471a866636b 819 Gene3D G3DSA:1.10.1780.10 2 106 3.4E-37 T 22-04-2016 IPR004176 Clp, N-terminal GO:0019538 L21SP4_RS10330 3b6010a5153eea3b45d7c471a866636b 819 Gene3D G3DSA:1.10.1780.10 107 149 1.0E-10 T 22-04-2016 IPR004176 Clp, N-terminal GO:0019538 L21SP4_RS10330 3b6010a5153eea3b45d7c471a866636b 819 SUPERFAMILY SSF52540 173 479 4.18E-72 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS10330 3b6010a5153eea3b45d7c471a866636b 819 Pfam PF07724 AAA domain (Cdc48 subfamily) 548 720 8.8E-50 T 22-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 L21SP4_RS10330 3b6010a5153eea3b45d7c471a866636b 819 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 217 329 6.3E-12 T 22-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 L21SP4_RS10330 3b6010a5153eea3b45d7c471a866636b 819 Gene3D G3DSA:3.40.50.300 503 675 4.6E-51 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS10330 3b6010a5153eea3b45d7c471a866636b 819 Gene3D G3DSA:3.40.50.300 709 735 4.6E-51 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS10330 3b6010a5153eea3b45d7c471a866636b 819 Gene3D G3DSA:1.10.8.60 736 816 9.5E-28 T 22-04-2016 L21SP4_RS02290 7062a066fe67512c2678c10c37c3fac7 414 PANTHER PTHR32432 1 393 2.0E-73 T 22-04-2016 L21SP4_RS02290 7062a066fe67512c2678c10c37c3fac7 414 SUPERFAMILY SSF53067 200 378 2.85E-31 T 22-04-2016 L21SP4_RS02290 7062a066fe67512c2678c10c37c3fac7 414 Pfam PF14450 Cell division protein FtsA 208 376 9.1E-18 T 22-04-2016 L21SP4_RS02290 7062a066fe67512c2678c10c37c3fac7 414 Gene3D G3DSA:3.30.420.40 1 141 5.0E-18 T 22-04-2016 L21SP4_RS02290 7062a066fe67512c2678c10c37c3fac7 414 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 8 378 2.3E-77 T 22-04-2016 IPR020823 Cell division protein FtsA GO:0007049 L21SP4_RS02290 7062a066fe67512c2678c10c37c3fac7 414 SMART SM00842 6 197 2.3E-40 T 22-04-2016 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 L21SP4_RS02290 7062a066fe67512c2678c10c37c3fac7 414 SUPERFAMILY SSF53067 6 194 1.6E-30 T 22-04-2016 L21SP4_RS02290 7062a066fe67512c2678c10c37c3fac7 414 Hamap MF_02033 Cell division protein FtsA [ftsA]. 2 398 20.491 T 22-04-2016 IPR020823 Cell division protein FtsA GO:0007049 L21SP4_RS02290 7062a066fe67512c2678c10c37c3fac7 414 Gene3D G3DSA:3.90.640.10 236 299 1.5E-7 T 22-04-2016 L21SP4_RS02290 7062a066fe67512c2678c10c37c3fac7 414 PANTHER PTHR32432:SF4 1 393 2.0E-73 T 22-04-2016 L21SP4_RS02290 7062a066fe67512c2678c10c37c3fac7 414 Pfam PF02491 SHS2 domain inserted in FTSA 103 162 4.2E-11 T 22-04-2016 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 L21SP4_RS02290 7062a066fe67512c2678c10c37c3fac7 414 Gene3D G3DSA:3.30.420.40 198 235 2.7E-22 T 22-04-2016 L21SP4_RS02290 7062a066fe67512c2678c10c37c3fac7 414 Gene3D G3DSA:3.30.420.40 300 353 2.7E-22 T 22-04-2016 L21SP4_RS02290 7062a066fe67512c2678c10c37c3fac7 414 PIRSF PIRSF003101 1 408 3.8E-87 T 22-04-2016 IPR020823 Cell division protein FtsA GO:0007049 L21SP4_RS02595 4406171a5ba9b1a55deb58f10064bda5 932 Gene3D G3DSA:2.60.120.260 735 855 2.6E-14 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS02595 4406171a5ba9b1a55deb58f10064bda5 932 PANTHER PTHR22925 1 361 6.9E-100 T 22-04-2016 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 L21SP4_RS02595 4406171a5ba9b1a55deb58f10064bda5 932 SUPERFAMILY SSF49785 732 860 2.72E-19 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS02595 4406171a5ba9b1a55deb58f10064bda5 932 Pfam PF17132 alpha-L-rhamnosidase 137 689 1.1E-162 T 22-04-2016 IPR033400 Alpha-L-rhamnosidase RhaM L21SP4_RS02595 4406171a5ba9b1a55deb58f10064bda5 932 Pfam PF17132 alpha-L-rhamnosidase 1 123 4.0E-42 T 22-04-2016 IPR033400 Alpha-L-rhamnosidase RhaM L21SP4_RS02595 4406171a5ba9b1a55deb58f10064bda5 932 PANTHER PTHR22925:SF40 1 361 6.9E-100 T 22-04-2016 L21SP4_RS01660 4ee3a3bc6232dd36653645589f0071a3 1183 Gene3D G3DSA:3.30.70.20 678 794 6.7E-18 T 22-04-2016 L21SP4_RS01660 4ee3a3bc6232dd36653645589f0071a3 1183 SUPERFAMILY SSF53323 424 674 1.12E-80 T 22-04-2016 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 L21SP4_RS01660 4ee3a3bc6232dd36653645589f0071a3 1183 Gene3D G3DSA:3.40.920.10 424 628 4.7E-79 T 22-04-2016 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 L21SP4_RS01660 4ee3a3bc6232dd36653645589f0071a3 1183 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 695 706 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site L21SP4_RS01660 4ee3a3bc6232dd36653645589f0071a3 1183 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 752 763 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site L21SP4_RS01660 4ee3a3bc6232dd36653645589f0071a3 1183 Gene3D G3DSA:4.10.780.10 635 674 1.1E-18 T 22-04-2016 IPR019456 Pyruvate-flavodoxin oxidoreductase, EKR domain GO:0016903|GO:0055114 L21SP4_RS01660 4ee3a3bc6232dd36653645589f0071a3 1183 SUPERFAMILY SSF52518 5 259 1.38E-72 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold L21SP4_RS01660 4ee3a3bc6232dd36653645589f0071a3 1183 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 432 615 9.7E-30 T 22-04-2016 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 L21SP4_RS01660 4ee3a3bc6232dd36653645589f0071a3 1183 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 270 352 4.0E-12 T 22-04-2016 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II L21SP4_RS01660 4ee3a3bc6232dd36653645589f0071a3 1183 Pfam PF10371 Domain of unknown function 631 683 5.2E-23 T 22-04-2016 IPR019456 Pyruvate-flavodoxin oxidoreductase, EKR domain GO:0016903|GO:0055114 L21SP4_RS01660 4ee3a3bc6232dd36653645589f0071a3 1183 PANTHER PTHR32154:SF0 4 1182 0.0 T 22-04-2016 L21SP4_RS01660 4ee3a3bc6232dd36653645589f0071a3 1183 PANTHER PTHR32154 4 1182 0.0 T 22-04-2016 L21SP4_RS01660 4ee3a3bc6232dd36653645589f0071a3 1183 TIGRFAM TIGR02176 pyruv_ox_red: pyruvate:ferredoxin (flavodoxin) oxidoreductase 7 1179 0.0 T 22-04-2016 IPR011895 Pyruvate-flavodoxin oxidoreductase GO:0005506|GO:0016903|GO:0022900|GO:0055114 L21SP4_RS01660 4ee3a3bc6232dd36653645589f0071a3 1183 Gene3D G3DSA:3.40.50.970 4 259 1.4E-105 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold L21SP4_RS01660 4ee3a3bc6232dd36653645589f0071a3 1183 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 18 248 4.4E-77 T 22-04-2016 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 L21SP4_RS01660 4ee3a3bc6232dd36653645589f0071a3 1183 Gene3D G3DSA:3.40.50.970 808 1180 2.8E-136 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold L21SP4_RS01660 4ee3a3bc6232dd36653645589f0071a3 1183 SUPERFAMILY SSF52518 801 1180 8.2E-125 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold L21SP4_RS01660 4ee3a3bc6232dd36653645589f0071a3 1183 SUPERFAMILY SSF54862 671 844 1.84E-21 T 22-04-2016 L21SP4_RS01660 4ee3a3bc6232dd36653645589f0071a3 1183 Gene3D G3DSA:3.40.50.920 260 421 1.3E-61 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 L21SP4_RS01660 4ee3a3bc6232dd36653645589f0071a3 1183 Pfam PF12838 4Fe-4S dicluster domain 695 764 2.4E-8 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain L21SP4_RS01660 4ee3a3bc6232dd36653645589f0071a3 1183 SUPERFAMILY SSF52922 260 421 2.43E-44 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 L21SP4_RS01660 4ee3a3bc6232dd36653645589f0071a3 1183 PIRSF PIRSF000159 1 1183 0.0 T 22-04-2016 IPR011895 Pyruvate-flavodoxin oxidoreductase GO:0005506|GO:0016903|GO:0022900|GO:0055114 L21SP4_RS01660 4ee3a3bc6232dd36653645589f0071a3 1183 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 969 1080 9.0E-9 T 22-04-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 L21SP4_RS01660 4ee3a3bc6232dd36653645589f0071a3 1183 SMART SM00890 628 685 2.5E-30 T 22-04-2016 IPR019456 Pyruvate-flavodoxin oxidoreductase, EKR domain GO:0016903|GO:0055114 L21SP4_RS02175 45c6d75f46fcc102898ef93ed11cd71b 289 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 5 284 8.0E-108 T 22-04-2016 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 L21SP4_RS02175 45c6d75f46fcc102898ef93ed11cd71b 289 SMART SM01130 1 286 9.6E-130 T 22-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 L21SP4_RS02175 45c6d75f46fcc102898ef93ed11cd71b 289 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 38 55 - T 22-04-2016 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 L21SP4_RS02175 45c6d75f46fcc102898ef93ed11cd71b 289 SUPERFAMILY SSF51569 1 287 1.15E-98 T 22-04-2016 L21SP4_RS02175 45c6d75f46fcc102898ef93ed11cd71b 289 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 1 284 62.633 T 22-04-2016 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 L21SP4_RS02175 45c6d75f46fcc102898ef93ed11cd71b 289 Pfam PF00701 Dihydrodipicolinate synthetase family 2 283 3.0E-93 T 22-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 L21SP4_RS02175 45c6d75f46fcc102898ef93ed11cd71b 289 PRINTS PR00146 Dihydrodipicolinate synthase signature 71 89 2.0E-35 T 22-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 L21SP4_RS02175 45c6d75f46fcc102898ef93ed11cd71b 289 PRINTS PR00146 Dihydrodipicolinate synthase signature 103 119 2.0E-35 T 22-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 L21SP4_RS02175 45c6d75f46fcc102898ef93ed11cd71b 289 PRINTS PR00146 Dihydrodipicolinate synthase signature 35 56 2.0E-35 T 22-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 L21SP4_RS02175 45c6d75f46fcc102898ef93ed11cd71b 289 PRINTS PR00146 Dihydrodipicolinate synthase signature 127 144 2.0E-35 T 22-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 L21SP4_RS02175 45c6d75f46fcc102898ef93ed11cd71b 289 PANTHER PTHR12128 1 287 6.5E-126 T 22-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 L21SP4_RS02175 45c6d75f46fcc102898ef93ed11cd71b 289 PIRSF PIRSF001365 1 288 3.7E-95 T 22-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 L21SP4_RS02175 45c6d75f46fcc102898ef93ed11cd71b 289 Gene3D G3DSA:3.20.20.70 1 287 2.9E-110 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP4_RS02175 45c6d75f46fcc102898ef93ed11cd71b 289 PANTHER PTHR12128:SF34 1 287 6.5E-126 T 22-04-2016 L21SP4_RS10930 16f6cf288d170426814baf4b28df7e7b 377 PANTHER PTHR13693:SF53 2 377 1.0E-152 T 22-04-2016 L21SP4_RS10930 16f6cf288d170426814baf4b28df7e7b 377 Gene3D G3DSA:3.40.640.10 53 269 9.7E-88 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 L21SP4_RS10930 16f6cf288d170426814baf4b28df7e7b 377 Gene3D G3DSA:3.90.1150.10 270 376 4.9E-23 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 L21SP4_RS10930 16f6cf288d170426814baf4b28df7e7b 377 Pfam PF00155 Aminotransferase class I and II 36 375 4.9E-59 T 22-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 L21SP4_RS10930 16f6cf288d170426814baf4b28df7e7b 377 TIGRFAM TIGR00858 bioF: 8-amino-7-oxononanoate synthase 22 375 3.6E-132 T 22-04-2016 IPR004723 8-amino-7-oxononanoate synthase, Archaea/Proteobacteria type GO:0008710|GO:0009102 KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147|UniPathway: UPA00078 L21SP4_RS10930 16f6cf288d170426814baf4b28df7e7b 377 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 233 242 - T 22-04-2016 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 L21SP4_RS10930 16f6cf288d170426814baf4b28df7e7b 377 PANTHER PTHR13693 2 377 1.0E-152 T 22-04-2016 L21SP4_RS10930 16f6cf288d170426814baf4b28df7e7b 377 SUPERFAMILY SSF53383 14 376 1.25E-104 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase L21SP4_RS09015 79e333428a1eaaf054b5896121172227 94 TIGRFAM TIGR00251 TIGR00251: TIGR00251 family protein 6 83 1.9E-18 T 22-04-2016 IPR005228 Conserved hypothetical protein CHP00251 L21SP4_RS09015 79e333428a1eaaf054b5896121172227 94 SUPERFAMILY SSF69786 2 86 9.02E-25 T 22-04-2016 IPR003746 Protein of unknown function DUF167 L21SP4_RS09015 79e333428a1eaaf054b5896121172227 94 SMART SM01152 7 83 2.7E-33 T 22-04-2016 IPR003746 Protein of unknown function DUF167 L21SP4_RS09015 79e333428a1eaaf054b5896121172227 94 Gene3D G3DSA:3.30.1200.10 2 93 7.2E-27 T 22-04-2016 IPR003746 Protein of unknown function DUF167 L21SP4_RS09015 79e333428a1eaaf054b5896121172227 94 Hamap MF_00634 UPF0235 protein YggU [yggU]. 7 94 19.046 T 22-04-2016 IPR003746 Protein of unknown function DUF167 L21SP4_RS09015 79e333428a1eaaf054b5896121172227 94 Pfam PF02594 Uncharacterised ACR, YggU family COG1872 10 81 1.6E-22 T 22-04-2016 IPR003746 Protein of unknown function DUF167 L21SP4_RS08105 3a653968fcf92ee42aa6cbc072a642a5 196 Pfam PF00717 Peptidase S24-like 113 176 1.0E-12 T 22-04-2016 IPR019759 Peptidase S24/S26A/S26B L21SP4_RS08105 3a653968fcf92ee42aa6cbc072a642a5 196 SUPERFAMILY SSF46785 12 60 1.03E-6 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS08105 3a653968fcf92ee42aa6cbc072a642a5 196 Gene3D G3DSA:2.10.109.10 76 195 1.3E-35 T 22-04-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain L21SP4_RS08105 3a653968fcf92ee42aa6cbc072a642a5 196 PANTHER PTHR33516 1 196 3.1E-41 T 22-04-2016 L21SP4_RS08105 3a653968fcf92ee42aa6cbc072a642a5 196 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 149 161 3.5E-6 T 22-04-2016 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 L21SP4_RS08105 3a653968fcf92ee42aa6cbc072a642a5 196 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 110 120 3.5E-6 T 22-04-2016 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 L21SP4_RS08105 3a653968fcf92ee42aa6cbc072a642a5 196 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 121 132 3.5E-6 T 22-04-2016 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 L21SP4_RS08105 3a653968fcf92ee42aa6cbc072a642a5 196 SUPERFAMILY SSF51306 74 193 7.19E-31 T 22-04-2016 IPR015927 Peptidase S24/S26A/S26B/S26C L21SP4_RS08105 3a653968fcf92ee42aa6cbc072a642a5 196 Gene3D G3DSA:1.10.10.10 12 60 1.6E-6 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS09565 dd094f6fc9757935d0ca105d064814c9 243 Pfam PF00977 Histidine biosynthesis protein 3 231 3.1E-71 T 22-04-2016 IPR006062 Histidine biosynthesis GO:0000105 L21SP4_RS09565 dd094f6fc9757935d0ca105d064814c9 243 PANTHER PTHR21235 1 233 1.9E-91 T 22-04-2016 L21SP4_RS09565 dd094f6fc9757935d0ca105d064814c9 243 SUPERFAMILY SSF51366 1 232 9.42E-67 T 22-04-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 L21SP4_RS09565 dd094f6fc9757935d0ca105d064814c9 243 PANTHER PTHR21235:SF15 1 233 1.9E-91 T 22-04-2016 L21SP4_RS09565 dd094f6fc9757935d0ca105d064814c9 243 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 3 233 6.9E-75 T 22-04-2016 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16|UniPathway: UPA00031 L21SP4_RS09565 dd094f6fc9757935d0ca105d064814c9 243 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 2 239 33.318 T 22-04-2016 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16|UniPathway: UPA00031 L21SP4_RS09565 dd094f6fc9757935d0ca105d064814c9 243 Gene3D G3DSA:3.20.20.70 1 233 2.4E-77 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP4_RS09250 3c1671d45aa9dba7e099e38cd8f4ddaa 168 PANTHER PTHR36966:SF1 8 166 1.8E-18 T 22-04-2016 L21SP4_RS09250 3c1671d45aa9dba7e099e38cd8f4ddaa 168 Pfam PF01797 Transposase IS200 like 16 120 1.1E-4 T 22-04-2016 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 L21SP4_RS09250 3c1671d45aa9dba7e099e38cd8f4ddaa 168 PANTHER PTHR36966 8 166 1.8E-18 T 22-04-2016 L21SP4_RS09250 3c1671d45aa9dba7e099e38cd8f4ddaa 168 SUPERFAMILY SSF143422 8 127 1.44E-16 T 22-04-2016 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 L21SP4_RS09250 3c1671d45aa9dba7e099e38cd8f4ddaa 168 SMART SM01321 5 121 4.2E-11 T 22-04-2016 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 L21SP4_RS09250 3c1671d45aa9dba7e099e38cd8f4ddaa 168 Gene3D G3DSA:3.30.70.1290 10 125 1.4E-8 T 22-04-2016 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 L21SP4_RS04230 be709360cc2297464e17693845284286 332 Gene3D G3DSA:3.40.50.300 30 193 7.6E-38 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS04230 be709360cc2297464e17693845284286 332 SUPERFAMILY SSF52540 35 169 2.92E-11 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS04230 be709360cc2297464e17693845284286 332 PANTHER PTHR11088 20 310 1.0E-66 T 22-04-2016 L21SP4_RS04230 be709360cc2297464e17693845284286 332 Pfam PF01715 IPP transferase 67 299 1.2E-60 T 22-04-2016 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781 L21SP4_RS04230 be709360cc2297464e17693845284286 332 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 33 323 24.38 T 22-04-2016 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781 L21SP4_RS04230 be709360cc2297464e17693845284286 332 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 35 306 1.3E-57 T 22-04-2016 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781 L21SP4_RS04230 be709360cc2297464e17693845284286 332 Gene3D G3DSA:1.10.287.890 218 297 5.6E-25 T 22-04-2016 L21SP4_RS07845 68642d2c05cc7e1fe96e1e0c8a1aab66 123 PANTHER PTHR33238:SF1 6 123 1.0E-32 T 22-04-2016 L21SP4_RS07845 68642d2c05cc7e1fe96e1e0c8a1aab66 123 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 69 123 5.9E-15 T 22-04-2016 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 L21SP4_RS07845 68642d2c05cc7e1fe96e1e0c8a1aab66 123 SUPERFAMILY SSF47979 69 123 2.35E-14 T 22-04-2016 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 L21SP4_RS07845 68642d2c05cc7e1fe96e1e0c8a1aab66 123 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 11 64 5.1E-15 T 22-04-2016 IPR022687 DTXR-type HTH domain GO:0003677 L21SP4_RS07845 68642d2c05cc7e1fe96e1e0c8a1aab66 123 Gene3D G3DSA:1.10.60.10 81 123 9.4E-13 T 22-04-2016 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 L21SP4_RS07845 68642d2c05cc7e1fe96e1e0c8a1aab66 123 PANTHER PTHR33238 6 123 1.0E-32 T 22-04-2016 L21SP4_RS07845 68642d2c05cc7e1fe96e1e0c8a1aab66 123 SMART SM00529 30 123 1.7E-20 T 22-04-2016 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 L21SP4_RS07845 68642d2c05cc7e1fe96e1e0c8a1aab66 123 Gene3D G3DSA:1.10.10.10 9 76 2.2E-24 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS07845 68642d2c05cc7e1fe96e1e0c8a1aab66 123 SUPERFAMILY SSF46785 9 68 5.79E-15 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS05555 c5acada0db01d712bb2a8d258d8c5554 546 TIGRFAM TIGR03663 TIGR03663: TIGR03663 family protein 11 445 2.8E-51 T 22-04-2016 IPR019962 Conserved hypothetical protein CHP03663 L21SP4_RS05555 c5acada0db01d712bb2a8d258d8c5554 546 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 84 224 1.6E-12 T 22-04-2016 L21SP4_RS03655 cbd0e174765286fdcc187898efd99239 834 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 6 809 2.9E-297 T 22-04-2016 IPR005748 DNA mismatch repair protein MutS, type 1 GO:0005524|GO:0006298|GO:0030983 L21SP4_RS03655 cbd0e174765286fdcc187898efd99239 834 Gene3D G3DSA:3.40.1170.10 3 114 2.6E-43 T 22-04-2016 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 L21SP4_RS03655 cbd0e174765286fdcc187898efd99239 834 Pfam PF00488 MutS domain V 615 804 2.1E-83 T 22-04-2016 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 L21SP4_RS03655 cbd0e174765286fdcc187898efd99239 834 Pfam PF05190 MutS family domain IV 431 522 3.1E-30 T 22-04-2016 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 L21SP4_RS03655 cbd0e174765286fdcc187898efd99239 834 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 5 820 24.507 T 22-04-2016 IPR005748 DNA mismatch repair protein MutS, type 1 GO:0005524|GO:0006298|GO:0030983 L21SP4_RS03655 cbd0e174765286fdcc187898efd99239 834 SUPERFAMILY SSF55271 3 109 4.32E-36 T 22-04-2016 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 L21SP4_RS03655 cbd0e174765286fdcc187898efd99239 834 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 693 709 - T 22-04-2016 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 L21SP4_RS03655 cbd0e174765286fdcc187898efd99239 834 Pfam PF05192 MutS domain III 270 562 9.3E-43 T 22-04-2016 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 L21SP4_RS03655 cbd0e174765286fdcc187898efd99239 834 SMART SM00533 286 594 4.8E-108 T 22-04-2016 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 L21SP4_RS03655 cbd0e174765286fdcc187898efd99239 834 PANTHER PTHR11361 6 830 0.0 T 22-04-2016 L21SP4_RS03655 cbd0e174765286fdcc187898efd99239 834 SUPERFAMILY SSF48334 267 567 2.49E-87 T 22-04-2016 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 L21SP4_RS03655 cbd0e174765286fdcc187898efd99239 834 SUPERFAMILY SSF52540 570 805 5.43E-62 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS03655 cbd0e174765286fdcc187898efd99239 834 Pfam PF01624 MutS domain I 6 113 3.7E-35 T 22-04-2016 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 L21SP4_RS03655 cbd0e174765286fdcc187898efd99239 834 SUPERFAMILY SSF53150 108 266 1.57E-39 T 22-04-2016 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 L21SP4_RS03655 cbd0e174765286fdcc187898efd99239 834 Gene3D G3DSA:1.10.1420.10 263 471 8.6E-53 T 22-04-2016 L21SP4_RS03655 cbd0e174765286fdcc187898efd99239 834 PANTHER PTHR11361:SF86 6 830 0.0 T 22-04-2016 L21SP4_RS03655 cbd0e174765286fdcc187898efd99239 834 Gene3D G3DSA:3.40.50.300 570 805 1.8E-88 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS03655 cbd0e174765286fdcc187898efd99239 834 Gene3D G3DSA:3.30.420.110 120 256 1.4E-38 T 22-04-2016 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 L21SP4_RS03655 cbd0e174765286fdcc187898efd99239 834 PIRSF PIRSF005813 111 831 6.0E-135 T 22-04-2016 IPR011184 DNA mismatch repair MutS GO:0005524|GO:0006298|GO:0030983 L21SP4_RS03655 cbd0e174765286fdcc187898efd99239 834 Pfam PF05188 MutS domain II 122 252 1.4E-24 T 22-04-2016 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 L21SP4_RS03655 cbd0e174765286fdcc187898efd99239 834 SMART SM00534 612 801 4.4E-120 T 22-04-2016 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 L21SP4_RS07645 34f34a62311c55eda48a20f535d30875 605 SUPERFAMILY SSF56784 348 587 2.36E-50 T 22-04-2016 IPR023214 HAD-like domain L21SP4_RS07645 34f34a62311c55eda48a20f535d30875 605 SUPERFAMILY SSF56784 290 309 2.36E-50 T 22-04-2016 IPR023214 HAD-like domain L21SP4_RS07645 34f34a62311c55eda48a20f535d30875 605 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 291 305 1.1E-19 T 22-04-2016 L21SP4_RS07645 34f34a62311c55eda48a20f535d30875 605 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 487 506 1.1E-19 T 22-04-2016 L21SP4_RS07645 34f34a62311c55eda48a20f535d30875 605 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 149 163 1.1E-19 T 22-04-2016 L21SP4_RS07645 34f34a62311c55eda48a20f535d30875 605 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 434 444 1.1E-19 T 22-04-2016 L21SP4_RS07645 34f34a62311c55eda48a20f535d30875 605 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 511 523 1.1E-19 T 22-04-2016 L21SP4_RS07645 34f34a62311c55eda48a20f535d30875 605 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 33 590 8.7E-121 T 22-04-2016 L21SP4_RS07645 34f34a62311c55eda48a20f535d30875 605 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 50 592 3.0E-136 T 22-04-2016 L21SP4_RS07645 34f34a62311c55eda48a20f535d30875 605 Gene3D G3DSA:2.70.150.10 72 199 8.3E-20 T 22-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 L21SP4_RS07645 34f34a62311c55eda48a20f535d30875 605 PANTHER PTHR24093:SF317 21 585 2.3E-140 T 22-04-2016 L21SP4_RS07645 34f34a62311c55eda48a20f535d30875 605 Pfam PF00122 E1-E2 ATPase 71 282 2.0E-54 T 22-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 L21SP4_RS07645 34f34a62311c55eda48a20f535d30875 605 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 73 571 2.1E-68 T 22-04-2016 IPR001757 P-type ATPase GO:0016021 L21SP4_RS07645 34f34a62311c55eda48a20f535d30875 605 Gene3D G3DSA:3.40.1110.10 308 413 1.0E-14 T 22-04-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 L21SP4_RS07645 34f34a62311c55eda48a20f535d30875 605 ProSitePatterns PS01229 Hypothetical cof family signature 2. 487 509 - T 22-04-2016 L21SP4_RS07645 34f34a62311c55eda48a20f535d30875 605 Gene3D G3DSA:3.40.50.1000 414 554 1.2E-38 T 22-04-2016 IPR023214 HAD-like domain L21SP4_RS07645 34f34a62311c55eda48a20f535d30875 605 Gene3D G3DSA:3.40.50.1000 266 307 1.2E-38 T 22-04-2016 IPR023214 HAD-like domain L21SP4_RS07645 34f34a62311c55eda48a20f535d30875 605 PANTHER PTHR24093 21 585 2.3E-140 T 22-04-2016 L21SP4_RS07645 34f34a62311c55eda48a20f535d30875 605 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 293 299 - T 22-04-2016 IPR018303 P-type ATPase, phosphorylation site L21SP4_RS07645 34f34a62311c55eda48a20f535d30875 605 SUPERFAMILY SSF81665 59 103 1.44E-8 T 22-04-2016 L21SP4_RS07645 34f34a62311c55eda48a20f535d30875 605 SUPERFAMILY SSF81665 200 285 1.44E-8 T 22-04-2016 L21SP4_RS07645 34f34a62311c55eda48a20f535d30875 605 Pfam PF00702 haloacid dehalogenase-like hydrolase 287 501 2.2E-37 T 22-04-2016 L21SP4_RS07645 34f34a62311c55eda48a20f535d30875 605 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 50 590 1.7E-163 T 22-04-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 L21SP4_RS07645 34f34a62311c55eda48a20f535d30875 605 SUPERFAMILY SSF81653 103 198 8.37E-21 T 22-04-2016 L21SP4_RS00295 3735ac715f843bfe8d2b2febd55a0fa4 247 Pfam PF01618 MotA/TolQ/ExbB proton channel family 120 231 3.9E-30 T 22-04-2016 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 L21SP4_RS00295 3735ac715f843bfe8d2b2febd55a0fa4 247 PANTHER PTHR30625:SF3 19 243 2.9E-41 T 22-04-2016 L21SP4_RS00295 3735ac715f843bfe8d2b2febd55a0fa4 247 PANTHER PTHR30625 19 243 2.9E-41 T 22-04-2016 L21SP4_RS05780 5b40d4757bacd0629264e4c296d06c0c 59 PRINTS PR00974 Ribosomal protein S18 family signature 36 50 2.4E-15 T 22-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS05780 5b40d4757bacd0629264e4c296d06c0c 59 PRINTS PR00974 Ribosomal protein S18 family signature 50 59 2.4E-15 T 22-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS05780 5b40d4757bacd0629264e4c296d06c0c 59 PRINTS PR00974 Ribosomal protein S18 family signature 28 35 2.4E-15 T 22-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS05780 5b40d4757bacd0629264e4c296d06c0c 59 PRINTS PR00974 Ribosomal protein S18 family signature 18 28 2.4E-15 T 22-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS05780 5b40d4757bacd0629264e4c296d06c0c 59 PANTHER PTHR13479 5 59 3.0E-21 T 22-04-2016 L21SP4_RS05780 5b40d4757bacd0629264e4c296d06c0c 59 Pfam PF01084 Ribosomal protein S18 8 57 7.1E-26 T 22-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS05780 5b40d4757bacd0629264e4c296d06c0c 59 Gene3D G3DSA:4.10.640.10 10 59 1.5E-25 T 22-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS05780 5b40d4757bacd0629264e4c296d06c0c 59 TIGRFAM TIGR00165 S18: ribosomal protein bS18 7 59 1.4E-24 T 22-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS05780 5b40d4757bacd0629264e4c296d06c0c 59 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 2 59 15.56 T 22-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS05780 5b40d4757bacd0629264e4c296d06c0c 59 SUPERFAMILY SSF46911 6 59 1.96E-21 T 22-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS05780 5b40d4757bacd0629264e4c296d06c0c 59 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 11 59 2.0E-13 T 22-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS07285 afb9eaadd04be6537b014aa0c940481f 253 Pfam PF01975 Survival protein SurE 3 186 3.2E-55 T 22-04-2016 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185 L21SP4_RS07285 afb9eaadd04be6537b014aa0c940481f 253 Hamap MF_00060 5'/3'-nucleotidase SurE [surE]. 1 253 36.051 T 22-04-2016 IPR030048 Survival protein SurE GO:0008252 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185 L21SP4_RS07285 afb9eaadd04be6537b014aa0c940481f 253 Gene3D G3DSA:3.40.1210.10 2 250 2.8E-81 T 22-04-2016 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185 L21SP4_RS07285 afb9eaadd04be6537b014aa0c940481f 253 TIGRFAM TIGR00087 surE: 5'/3'-nucleotidase SurE 2 237 1.9E-67 T 22-04-2016 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185 L21SP4_RS07285 afb9eaadd04be6537b014aa0c940481f 253 PANTHER PTHR30457 2 247 4.6E-83 T 22-04-2016 L21SP4_RS07285 afb9eaadd04be6537b014aa0c940481f 253 SUPERFAMILY SSF64167 2 247 6.67E-82 T 22-04-2016 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185 L21SP4_RS01230 3e675f537ccc6f706234a8556c9bb770 75 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 3 74 25.322 T 22-04-2016 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 L21SP4_RS01230 3e675f537ccc6f706234a8556c9bb770 75 Pfam PF01176 Translation initiation factor 1A / IF-1 10 72 1.2E-26 T 22-04-2016 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 L21SP4_RS01230 3e675f537ccc6f706234a8556c9bb770 75 PANTHER PTHR33370 4 75 1.5E-40 T 22-04-2016 L21SP4_RS01230 3e675f537ccc6f706234a8556c9bb770 75 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 5 73 2.9E-34 T 22-04-2016 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 L21SP4_RS01230 3e675f537ccc6f706234a8556c9bb770 75 SMART SM00316 4 74 1.3E-8 T 22-04-2016 IPR022967 RNA-binding domain, S1 L21SP4_RS01230 3e675f537ccc6f706234a8556c9bb770 75 SUPERFAMILY SSF50249 5 73 4.7E-27 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold L21SP4_RS01230 3e675f537ccc6f706234a8556c9bb770 75 Gene3D G3DSA:2.40.50.140 3 74 1.9E-36 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold L21SP4_RS09850 fafd95abc606ddbdde3e3138ccdd315e 224 Pfam PF00872 Transposase, Mutator family 1 184 7.9E-9 T 22-04-2016 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 L21SP4_RS06255 7b9e9f99f852789a06cb6612432a23dd 447 Gene3D G3DSA:3.40.50.300 74 319 8.5E-58 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS06255 7b9e9f99f852789a06cb6612432a23dd 447 Hamap MF_00310 V-type ATP synthase beta chain [atpB]. 2 432 45.49 T 22-04-2016 IPR022879 V-type ATP synthase regulatory subunit B/beta L21SP4_RS06255 7b9e9f99f852789a06cb6612432a23dd 447 SUPERFAMILY SSF52540 75 334 2.28E-57 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS06255 7b9e9f99f852789a06cb6612432a23dd 447 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 9 71 2.8E-7 T 22-04-2016 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 L21SP4_RS06255 7b9e9f99f852789a06cb6612432a23dd 447 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 127 318 6.0E-42 T 22-04-2016 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 L21SP4_RS06255 7b9e9f99f852789a06cb6612432a23dd 447 PANTHER PTHR15184 1 440 3.6E-143 T 22-04-2016 L21SP4_RS06255 7b9e9f99f852789a06cb6612432a23dd 447 PANTHER PTHR15184:SF11 1 440 3.6E-143 T 22-04-2016 L21SP4_RS10405 97ef675d6b3ec6a6aec708e8f133191d 474 Gene3D G3DSA:3.40.50.620 12 188 5.5E-14 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP4_RS10405 97ef675d6b3ec6a6aec708e8f133191d 474 PANTHER PTHR11807 19 465 4.6E-74 T 22-04-2016 L21SP4_RS10405 97ef675d6b3ec6a6aec708e8f133191d 474 SUPERFAMILY SSF52402 20 239 9.04E-53 T 22-04-2016 L21SP4_RS10405 97ef675d6b3ec6a6aec708e8f133191d 474 Pfam PF11734 TilS substrate C-terminal domain 391 458 5.4E-17 T 22-04-2016 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 L21SP4_RS10405 97ef675d6b3ec6a6aec708e8f133191d 474 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 23 210 6.6E-48 T 22-04-2016 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 L21SP4_RS10405 97ef675d6b3ec6a6aec708e8f133191d 474 SUPERFAMILY SSF82829 218 324 2.14E-10 T 22-04-2016 L21SP4_RS10405 97ef675d6b3ec6a6aec708e8f133191d 474 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 4 318 23.025 T 22-04-2016 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 L21SP4_RS10405 97ef675d6b3ec6a6aec708e8f133191d 474 PANTHER PTHR11807:SF2 19 465 4.6E-74 T 22-04-2016 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 L21SP4_RS10405 97ef675d6b3ec6a6aec708e8f133191d 474 SMART SM00977 391 465 1.0E-25 T 22-04-2016 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 L21SP4_RS10405 97ef675d6b3ec6a6aec708e8f133191d 474 Pfam PF01171 PP-loop family 23 206 6.8E-47 T 22-04-2016 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal L21SP4_RS10405 97ef675d6b3ec6a6aec708e8f133191d 474 TIGRFAM TIGR02433 lysidine_TilS_C: tRNA(Ile)-lysidine synthetase, C-terminal domain 391 435 2.7E-15 T 22-04-2016 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 L21SP4_RS10405 97ef675d6b3ec6a6aec708e8f133191d 474 SUPERFAMILY SSF56037 338 458 1.54E-20 T 22-04-2016 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 L21SP4_RS10405 97ef675d6b3ec6a6aec708e8f133191d 474 Pfam PF09179 TilS substrate binding domain 260 324 3.8E-6 T 22-04-2016 IPR015262 tRNA(Ile)-lysidine synthase , substrate-binding domain GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 L21SP4_RS00095 98dbdf38d023466d62558bc1dcb625ee 248 Pfam PF00588 SpoU rRNA Methylase family 8 158 1.1E-30 T 22-04-2016 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 L21SP4_RS00095 98dbdf38d023466d62558bc1dcb625ee 248 PANTHER PTHR12029 7 188 3.2E-25 T 22-04-2016 L21SP4_RS00095 98dbdf38d023466d62558bc1dcb625ee 248 TIGRFAM TIGR00050 rRNA_methyl_1: RNA methyltransferase, TrmH family, group 1 6 237 7.9E-55 T 22-04-2016 IPR004384 RNA methyltransferase TrmH, group 1 GO:0006396|GO:0008173 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 L21SP4_RS00095 98dbdf38d023466d62558bc1dcb625ee 248 Gene3D G3DSA:3.40.1280.10 7 163 2.0E-30 T 22-04-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal L21SP4_RS00095 98dbdf38d023466d62558bc1dcb625ee 248 PIRSF PIRSF004808 3 244 3.9E-67 T 22-04-2016 IPR004384 RNA methyltransferase TrmH, group 1 GO:0006396|GO:0008173 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 L21SP4_RS00095 98dbdf38d023466d62558bc1dcb625ee 248 SUPERFAMILY SSF75217 7 165 7.19E-32 T 22-04-2016 IPR029028 Alpha/beta knot methyltransferases L21SP4_RS09920 65a0f6b5aa6a813e66ba80a1089c1d00 525 Gene3D G3DSA:1.10.287.130 267 336 2.2E-17 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS09920 65a0f6b5aa6a813e66ba80a1089c1d00 525 SMART SM00304 85 137 1.2E-7 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 L21SP4_RS09920 65a0f6b5aa6a813e66ba80a1089c1d00 525 SUPERFAMILY SSF55874 330 506 3.01E-40 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS09920 65a0f6b5aa6a813e66ba80a1089c1d00 525 Gene3D G3DSA:3.30.450.20 129 253 6.4E-26 T 22-04-2016 L21SP4_RS09920 65a0f6b5aa6a813e66ba80a1089c1d00 525 SMART SM00091 144 210 2.1E-12 T 22-04-2016 IPR000014 PAS domain L21SP4_RS09920 65a0f6b5aa6a813e66ba80a1089c1d00 525 Pfam PF08448 PAS fold 150 257 4.1E-14 T 22-04-2016 IPR013656 PAS fold-4 L21SP4_RS09920 65a0f6b5aa6a813e66ba80a1089c1d00 525 Gene3D G3DSA:3.30.565.10 341 507 7.1E-43 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS09920 65a0f6b5aa6a813e66ba80a1089c1d00 525 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 388 505 9.8E-26 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS09920 65a0f6b5aa6a813e66ba80a1089c1d00 525 Pfam PF00672 HAMP domain 66 130 2.3E-13 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 L21SP4_RS09920 65a0f6b5aa6a813e66ba80a1089c1d00 525 SMART SM00388 275 340 6.7E-22 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS09920 65a0f6b5aa6a813e66ba80a1089c1d00 525 PRINTS PR00344 Bacterial sensor protein C-terminal signature 466 484 1.3E-14 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS09920 65a0f6b5aa6a813e66ba80a1089c1d00 525 PRINTS PR00344 Bacterial sensor protein C-terminal signature 431 445 1.3E-14 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS09920 65a0f6b5aa6a813e66ba80a1089c1d00 525 PRINTS PR00344 Bacterial sensor protein C-terminal signature 490 503 1.3E-14 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS09920 65a0f6b5aa6a813e66ba80a1089c1d00 525 PRINTS PR00344 Bacterial sensor protein C-terminal signature 449 459 1.3E-14 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS09920 65a0f6b5aa6a813e66ba80a1089c1d00 525 SUPERFAMILY SSF47384 262 341 4.71E-20 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS09920 65a0f6b5aa6a813e66ba80a1089c1d00 525 SMART SM00387 387 506 3.1E-35 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS09920 65a0f6b5aa6a813e66ba80a1089c1d00 525 PANTHER PTHR24423 128 506 7.9E-112 T 22-04-2016 L21SP4_RS09920 65a0f6b5aa6a813e66ba80a1089c1d00 525 PANTHER PTHR24423 1 6 7.9E-112 T 22-04-2016 L21SP4_RS09920 65a0f6b5aa6a813e66ba80a1089c1d00 525 SUPERFAMILY SSF55785 129 253 2.58E-26 T 22-04-2016 IPR000014 PAS domain L21SP4_RS09920 65a0f6b5aa6a813e66ba80a1089c1d00 525 Pfam PF00512 His Kinase A (phospho-acceptor) domain 276 340 8.8E-18 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS09920 65a0f6b5aa6a813e66ba80a1089c1d00 525 SUPERFAMILY SSF158472 85 133 3.79E-9 T 22-04-2016 L21SP4_RS09920 65a0f6b5aa6a813e66ba80a1089c1d00 525 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 140 261 1.4E-25 T 22-04-2016 IPR000014 PAS domain L21SP4_RS02405 06f1bc9c0b53769ee5c2d977000099f0 185 SUPERFAMILY SSF50104 1 63 7.52E-19 T 22-04-2016 IPR008991 Translation protein SH3-like domain L21SP4_RS02405 06f1bc9c0b53769ee5c2d977000099f0 185 Gene3D G3DSA:2.30.30.30 1 63 4.5E-25 T 22-04-2016 IPR014722 Ribosomal protein L2 domain 2 L21SP4_RS02405 06f1bc9c0b53769ee5c2d977000099f0 185 Gene3D G3DSA:2.40.50.140 128 185 2.4E-25 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold L21SP4_RS02405 06f1bc9c0b53769ee5c2d977000099f0 185 SMART SM01185 67 121 2.9E-22 T 22-04-2016 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 UniPathway: UPA00345 L21SP4_RS02405 06f1bc9c0b53769ee5c2d977000099f0 185 Gene3D G3DSA:2.40.50.140 65 126 4.3E-22 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold L21SP4_RS02405 06f1bc9c0b53769ee5c2d977000099f0 185 ProSitePatterns PS01275 Elongation factor P signature. 150 169 - T 22-04-2016 IPR013852 Translation elongation factor P/YeiP, conserved site UniPathway: UPA00345 L21SP4_RS02405 06f1bc9c0b53769ee5c2d977000099f0 185 SUPERFAMILY SSF50249 65 126 9.42E-17 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold L21SP4_RS02405 06f1bc9c0b53769ee5c2d977000099f0 185 Pfam PF09285 Elongation factor P, C-terminal 129 184 1.5E-23 T 22-04-2016 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 UniPathway: UPA00345 L21SP4_RS02405 06f1bc9c0b53769ee5c2d977000099f0 185 SUPERFAMILY SSF50249 128 185 4.97E-17 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold L21SP4_RS02405 06f1bc9c0b53769ee5c2d977000099f0 185 PANTHER PTHR30053 1 185 1.6E-77 T 22-04-2016 L21SP4_RS02405 06f1bc9c0b53769ee5c2d977000099f0 185 SMART SM00841 129 184 6.3E-29 T 22-04-2016 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 UniPathway: UPA00345 L21SP4_RS02405 06f1bc9c0b53769ee5c2d977000099f0 185 Pfam PF01132 Elongation factor P (EF-P) OB domain 68 121 3.4E-20 T 22-04-2016 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 UniPathway: UPA00345 L21SP4_RS02405 06f1bc9c0b53769ee5c2d977000099f0 185 Hamap MF_00141 Elongation factor P [efp]. 1 185 45.031 T 22-04-2016 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 UniPathway: UPA00345 L21SP4_RS02405 06f1bc9c0b53769ee5c2d977000099f0 185 PIRSF PIRSF005901 1 185 1.9E-63 T 22-04-2016 IPR020599 Translation elongation factor P/YeiP UniPathway: UPA00345 L21SP4_RS02405 06f1bc9c0b53769ee5c2d977000099f0 185 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 60 7.5E-24 T 22-04-2016 IPR013185 Translation elongation factor, KOW-like UniPathway: UPA00345 L21SP4_RS02405 06f1bc9c0b53769ee5c2d977000099f0 185 TIGRFAM TIGR00038 efp: translation elongation factor P 2 185 6.1E-71 T 22-04-2016 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 UniPathway: UPA00345 L21SP4_RS11990 894cb3d3d63ebe8b0bf79f58f1f6cf79 486 SUPERFAMILY SSF53649 3 435 1.7E-94 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS11990 894cb3d3d63ebe8b0bf79f58f1f6cf79 486 PANTHER PTHR10342 3 460 5.9E-77 T 22-04-2016 L21SP4_RS11990 894cb3d3d63ebe8b0bf79f58f1f6cf79 486 Pfam PF00884 Sulfatase 5 330 2.2E-55 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS11990 894cb3d3d63ebe8b0bf79f58f1f6cf79 486 ProSitePatterns PS00149 Sulfatases signature 2. 94 104 - T 22-04-2016 IPR024607 Sulfatase, conserved site L21SP4_RS11990 894cb3d3d63ebe8b0bf79f58f1f6cf79 486 Gene3D G3DSA:3.30.1120.10 365 443 8.9E-11 T 22-04-2016 L21SP4_RS11990 894cb3d3d63ebe8b0bf79f58f1f6cf79 486 Gene3D G3DSA:3.40.720.10 5 345 1.8E-80 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS03285 7d83523cddb671611a6a570ef37d7bf9 1207 PANTHER PTHR16026 812 1195 8.0E-39 T 22-04-2016 IPR027039 Cartilage acidic protein 1 L21SP4_RS03285 7d83523cddb671611a6a570ef37d7bf9 1207 SUPERFAMILY SSF69318 777 1065 2.49E-42 T 22-04-2016 L21SP4_RS03285 7d83523cddb671611a6a570ef37d7bf9 1207 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 916 984 1.6E-13 T 22-04-2016 L21SP4_RS03285 7d83523cddb671611a6a570ef37d7bf9 1207 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 816 874 1.9E-10 T 22-04-2016 L21SP4_RS03285 7d83523cddb671611a6a570ef37d7bf9 1207 PANTHER PTHR16026:SF0 812 1195 8.0E-39 T 22-04-2016 L21SP4_RS03285 7d83523cddb671611a6a570ef37d7bf9 1207 Pfam PF07593 ASPIC and UnbV 1131 1197 2.0E-17 T 22-04-2016 IPR011519 ASPIC/UnbV L21SP4_RS03285 7d83523cddb671611a6a570ef37d7bf9 1207 Gene3D G3DSA:2.130.10.130 772 865 2.5E-10 T 22-04-2016 L21SP4_RS03285 7d83523cddb671611a6a570ef37d7bf9 1207 Gene3D G3DSA:2.130.10.130 866 1107 1.6E-22 T 22-04-2016 L21SP4_RS02550 5ba66e6248f793e7c6937caed258574e 539 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 23 503 9.6E-187 T 22-04-2016 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 L21SP4_RS02550 5ba66e6248f793e7c6937caed258574e 539 PANTHER PTHR30047:SF2 12 524 7.0E-213 T 22-04-2016 L21SP4_RS02550 5ba66e6248f793e7c6937caed258574e 539 PANTHER PTHR30047 12 524 7.0E-213 T 22-04-2016 L21SP4_RS02550 5ba66e6248f793e7c6937caed258574e 539 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 61 504 1.1E-149 T 22-04-2016 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 L21SP4_RS03345 9a825ad269c8491f21596446ca2e0df9 305 SUPERFAMILY SSF50249 232 294 2.23E-13 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold L21SP4_RS03345 9a825ad269c8491f21596446ca2e0df9 305 Pfam PF10544 T5orf172 domain 134 220 1.0E-14 T 22-04-2016 IPR018306 Bacteriophage T5, Orf172 DNA-binding L21SP4_RS03345 9a825ad269c8491f21596446ca2e0df9 305 SMART SM00974 142 222 6.7E-13 T 22-04-2016 IPR018306 Bacteriophage T5, Orf172 DNA-binding L21SP4_RS03345 9a825ad269c8491f21596446ca2e0df9 305 Pfam PF00313 'Cold-shock' DNA-binding domain 233 292 1.8E-11 T 22-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 L21SP4_RS03345 9a825ad269c8491f21596446ca2e0df9 305 Gene3D G3DSA:2.40.50.140 233 296 9.4E-15 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold L21SP4_RS03345 9a825ad269c8491f21596446ca2e0df9 305 SMART SM00357 233 296 2.0E-8 T 22-04-2016 IPR011129 Cold shock protein GO:0003676 L21SP4_RS00265 f52aec35987c3aa55b789dc24e450bba 566 Pfam PF00581 Rhodanese-like domain 470 560 6.8E-10 T 22-04-2016 IPR001763 Rhodanese-like domain L21SP4_RS00265 f52aec35987c3aa55b789dc24e450bba 566 SUPERFAMILY SSF55424 337 460 5.84E-27 T 22-04-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 L21SP4_RS00265 f52aec35987c3aa55b789dc24e450bba 566 PANTHER PTHR22912:SF140 1 454 1.1E-134 T 22-04-2016 L21SP4_RS00265 f52aec35987c3aa55b789dc24e450bba 566 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 115 133 1.6E-25 T 22-04-2016 L21SP4_RS00265 f52aec35987c3aa55b789dc24e450bba 566 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 275 297 1.6E-25 T 22-04-2016 L21SP4_RS00265 f52aec35987c3aa55b789dc24e450bba 566 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.6E-25 T 22-04-2016 L21SP4_RS00265 f52aec35987c3aa55b789dc24e450bba 566 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 162 180 1.6E-25 T 22-04-2016 L21SP4_RS00265 f52aec35987c3aa55b789dc24e450bba 566 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 247 263 1.6E-25 T 22-04-2016 L21SP4_RS00265 f52aec35987c3aa55b789dc24e450bba 566 Gene3D G3DSA:3.50.50.60 124 328 4.8E-50 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP4_RS00265 f52aec35987c3aa55b789dc24e450bba 566 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 248 262 4.3E-13 T 22-04-2016 L21SP4_RS00265 f52aec35987c3aa55b789dc24e450bba 566 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 162 187 4.3E-13 T 22-04-2016 L21SP4_RS00265 f52aec35987c3aa55b789dc24e450bba 566 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 4.3E-13 T 22-04-2016 L21SP4_RS00265 f52aec35987c3aa55b789dc24e450bba 566 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 290 297 4.3E-13 T 22-04-2016 L21SP4_RS00265 f52aec35987c3aa55b789dc24e450bba 566 SMART SM00450 467 566 5.6E-13 T 22-04-2016 IPR001763 Rhodanese-like domain L21SP4_RS00265 f52aec35987c3aa55b789dc24e450bba 566 SUPERFAMILY SSF51905 1 329 1.73E-46 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP4_RS00265 f52aec35987c3aa55b789dc24e450bba 566 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 344 446 9.9E-16 T 22-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 L21SP4_RS00265 f52aec35987c3aa55b789dc24e450bba 566 Gene3D G3DSA:3.40.250.10 456 560 4.5E-20 T 22-04-2016 IPR001763 Rhodanese-like domain L21SP4_RS00265 f52aec35987c3aa55b789dc24e450bba 566 Gene3D G3DSA:3.30.390.30 350 455 5.1E-31 T 22-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 L21SP4_RS00265 f52aec35987c3aa55b789dc24e450bba 566 PANTHER PTHR22912 1 454 1.1E-134 T 22-04-2016 L21SP4_RS00265 f52aec35987c3aa55b789dc24e450bba 566 Gene3D G3DSA:3.50.50.60 2 123 2.5E-21 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP4_RS00265 f52aec35987c3aa55b789dc24e450bba 566 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 302 1.8E-59 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP4_RS00265 f52aec35987c3aa55b789dc24e450bba 566 SUPERFAMILY SSF52821 454 560 3.4E-23 T 22-04-2016 IPR001763 Rhodanese-like domain L21SP4_RS04250 597002d2f6c1047d7a1e570af0403f81 269 Pfam PF13720 Udp N-acetylglucosamine O-acyltransferase; Domain 2 172 254 2.5E-25 T 22-04-2016 IPR029098 Udp N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12|UniPathway: UPA00359 L21SP4_RS04250 597002d2f6c1047d7a1e570af0403f81 269 PANTHER PTHR23416 1 247 1.7E-97 T 22-04-2016 L21SP4_RS04250 597002d2f6c1047d7a1e570af0403f81 269 SUPERFAMILY SSF51161 1 254 1.18E-63 T 22-04-2016 IPR011004 Trimeric LpxA-like L21SP4_RS04250 597002d2f6c1047d7a1e570af0403f81 269 TIGRFAM TIGR01852 lipid_A_lpxA: acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase 1 254 5.3E-91 T 22-04-2016 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12|UniPathway: UPA00359 L21SP4_RS04250 597002d2f6c1047d7a1e570af0403f81 269 PANTHER PTHR23416:SF8 1 247 1.7E-97 T 22-04-2016 L21SP4_RS04250 597002d2f6c1047d7a1e570af0403f81 269 PIRSF PIRSF000456 1 263 1.8E-90 T 22-04-2016 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12|UniPathway: UPA00359 L21SP4_RS04250 597002d2f6c1047d7a1e570af0403f81 269 Gene3D G3DSA:1.20.1180.10 195 254 6.2E-22 T 22-04-2016 IPR029098 Udp N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12|UniPathway: UPA00359 L21SP4_RS04250 597002d2f6c1047d7a1e570af0403f81 269 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 28 62 5.7E-6 T 22-04-2016 IPR001451 Hexapeptide repeat L21SP4_RS04250 597002d2f6c1047d7a1e570af0403f81 269 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 102 135 1.3E-6 T 22-04-2016 IPR001451 Hexapeptide repeat L21SP4_RS04250 597002d2f6c1047d7a1e570af0403f81 269 Gene3D G3DSA:2.160.10.10 1 86 1.9E-20 T 22-04-2016 L21SP4_RS04250 597002d2f6c1047d7a1e570af0403f81 269 Gene3D G3DSA:2.160.10.10 87 194 6.9E-23 T 22-04-2016 L21SP4_RS10940 3ae82af72610fa26b1976e370413b565 373 Gene3D G3DSA:3.30.160.20 231 308 2.0E-38 T 22-04-2016 IPR014720 Double-stranded RNA-binding domain L21SP4_RS10940 3ae82af72610fa26b1976e370413b565 373 Gene3D G3DSA:1.20.58.410 1 119 6.3E-23 T 22-04-2016 L21SP4_RS10940 3ae82af72610fa26b1976e370413b565 373 Hamap MF_00094 Peptide chain release factor 2 [prfB]. 2 369 39.341 T 22-04-2016 IPR020853 Peptide chain release factor 2, bacterial GO:0005737|GO:0006415|GO:0016149 L21SP4_RS10940 3ae82af72610fa26b1976e370413b565 373 Pfam PF03462 PCRF domain 30 222 2.5E-56 T 22-04-2016 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 L21SP4_RS10940 3ae82af72610fa26b1976e370413b565 373 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 248 264 - T 22-04-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 L21SP4_RS10940 3ae82af72610fa26b1976e370413b565 373 SMART SM00937 84 198 4.4E-47 T 22-04-2016 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 L21SP4_RS10940 3ae82af72610fa26b1976e370413b565 373 SUPERFAMILY SSF75620 31 371 3.92E-130 T 22-04-2016 L21SP4_RS10940 3ae82af72610fa26b1976e370413b565 373 TIGRFAM TIGR00020 prfB: peptide chain release factor 2 1 368 4.3E-156 T 22-04-2016 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 L21SP4_RS10940 3ae82af72610fa26b1976e370413b565 373 Pfam PF00472 RF-1 domain 232 341 1.4E-40 T 22-04-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 L21SP4_RS10940 3ae82af72610fa26b1976e370413b565 373 PANTHER PTHR11075:SF6 1 373 1.5E-154 T 22-04-2016 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 L21SP4_RS10940 3ae82af72610fa26b1976e370413b565 373 PANTHER PTHR11075 1 373 1.5E-154 T 22-04-2016 L21SP4_RS02790 206914f67a68d787e53aff7e235e0b7f 451 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 119 132 - T 22-04-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 L21SP4_RS02790 206914f67a68d787e53aff7e235e0b7f 451 SMART SM00839 201 449 1.3E-85 T 22-04-2016 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 L21SP4_RS02790 206914f67a68d787e53aff7e235e0b7f 451 PANTHER PTHR11606:SF4 4 451 1.7E-241 T 22-04-2016 L21SP4_RS02790 206914f67a68d787e53aff7e235e0b7f 451 Gene3D G3DSA:1.10.285.10 376 450 1.4E-26 T 22-04-2016 L21SP4_RS02790 206914f67a68d787e53aff7e235e0b7f 451 Gene3D G3DSA:1.10.285.10 4 64 5.7E-25 T 22-04-2016 L21SP4_RS02790 206914f67a68d787e53aff7e235e0b7f 451 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 199 449 1.3E-83 T 22-04-2016 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 L21SP4_RS02790 206914f67a68d787e53aff7e235e0b7f 451 SUPERFAMILY SSF51735 199 450 1.18E-68 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS02790 206914f67a68d787e53aff7e235e0b7f 451 SUPERFAMILY SSF53223 3 193 7.68E-72 T 22-04-2016 L21SP4_RS02790 206914f67a68d787e53aff7e235e0b7f 451 PANTHER PTHR11606 4 451 1.7E-241 T 22-04-2016 L21SP4_RS02790 206914f67a68d787e53aff7e235e0b7f 451 Gene3D G3DSA:3.40.50.720 206 375 5.9E-60 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS02790 206914f67a68d787e53aff7e235e0b7f 451 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 232 252 4.9E-32 T 22-04-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 L21SP4_RS02790 206914f67a68d787e53aff7e235e0b7f 451 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 375 386 4.9E-32 T 22-04-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 L21SP4_RS02790 206914f67a68d787e53aff7e235e0b7f 451 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 111 125 4.9E-32 T 22-04-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 L21SP4_RS02790 206914f67a68d787e53aff7e235e0b7f 451 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 190 212 4.9E-32 T 22-04-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 L21SP4_RS02790 206914f67a68d787e53aff7e235e0b7f 451 PIRSF PIRSF000185 19 451 1.7E-113 T 22-04-2016 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 L21SP4_RS02790 206914f67a68d787e53aff7e235e0b7f 451 Gene3D G3DSA:3.40.192.10 65 185 1.2E-60 T 22-04-2016 L21SP4_RS02790 206914f67a68d787e53aff7e235e0b7f 451 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 54 182 1.4E-49 T 22-04-2016 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 L21SP4_RS09940 04ee065ea48669d8926c24be7d5988b1 418 SUPERFAMILY SSF53720 5 417 2.62E-121 T 22-04-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 L21SP4_RS09940 04ee065ea48669d8926c24be7d5988b1 418 Gene3D G3DSA:3.40.309.10 228 375 2.4E-43 T 22-04-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 L21SP4_RS09940 04ee065ea48669d8926c24be7d5988b1 418 PANTHER PTHR11063 5 418 1.7E-189 T 22-04-2016 L21SP4_RS09940 04ee065ea48669d8926c24be7d5988b1 418 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 16 407 6.5E-154 T 22-04-2016 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|UniPathway: UPA00098 L21SP4_RS09940 04ee065ea48669d8926c24be7d5988b1 418 PIRSF PIRSF000151 1 418 1.3E-185 T 22-04-2016 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|UniPathway: UPA00098 L21SP4_RS09940 04ee065ea48669d8926c24be7d5988b1 418 Pfam PF00171 Aldehyde dehydrogenase family 5 289 2.9E-19 T 22-04-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 L21SP4_RS09940 04ee065ea48669d8926c24be7d5988b1 418 Gene3D G3DSA:3.40.605.10 4 225 3.5E-106 T 22-04-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 L21SP4_RS09940 04ee065ea48669d8926c24be7d5988b1 418 Gene3D G3DSA:3.40.605.10 376 417 3.5E-106 T 22-04-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 L21SP4_RS09940 04ee065ea48669d8926c24be7d5988b1 418 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 6 417 42.302 T 22-04-2016 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|UniPathway: UPA00098 L21SP4_RS09940 04ee065ea48669d8926c24be7d5988b1 418 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 324 346 - T 22-04-2016 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|UniPathway: UPA00098 L21SP4_RS09940 04ee065ea48669d8926c24be7d5988b1 418 PANTHER PTHR11063:SF8 5 418 1.7E-189 T 22-04-2016 L21SP4_RS05640 9b222800ef48fe0db3de3b7dc2437031 268 Pfam PF02548 Ketopantoate hydroxymethyltransferase 3 258 5.5E-105 T 22-04-2016 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654|UniPathway: UPA00028 L21SP4_RS05640 9b222800ef48fe0db3de3b7dc2437031 268 Gene3D G3DSA:3.20.20.60 2 263 1.6E-109 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 L21SP4_RS05640 9b222800ef48fe0db3de3b7dc2437031 268 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 5 263 8.9E-95 T 22-04-2016 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654|UniPathway: UPA00028 L21SP4_RS05640 9b222800ef48fe0db3de3b7dc2437031 268 SUPERFAMILY SSF51621 3 263 1.22E-98 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 L21SP4_RS05640 9b222800ef48fe0db3de3b7dc2437031 268 PIRSF PIRSF000388 1 265 4.3E-103 T 22-04-2016 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654|UniPathway: UPA00028 L21SP4_RS05640 9b222800ef48fe0db3de3b7dc2437031 268 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 3 263 41.82 T 22-04-2016 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654|UniPathway: UPA00028 L21SP4_RS05640 9b222800ef48fe0db3de3b7dc2437031 268 PANTHER PTHR20881 2 263 1.5E-140 T 22-04-2016 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654|UniPathway: UPA00028 L21SP4_RS05470 27fd2d8d69fa5db134e55de90451bbdc 689 Gene3D G3DSA:3.40.50.300 279 339 1.2E-48 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS05470 27fd2d8d69fa5db134e55de90451bbdc 689 Gene3D G3DSA:3.40.50.300 8 91 1.2E-48 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS05470 27fd2d8d69fa5db134e55de90451bbdc 689 Gene3D G3DSA:3.40.50.300 389 410 1.2E-48 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS05470 27fd2d8d69fa5db134e55de90451bbdc 689 SMART SM00490 460 546 4.4E-17 T 22-04-2016 IPR001650 Helicase, C-terminal L21SP4_RS05470 27fd2d8d69fa5db134e55de90451bbdc 689 SUPERFAMILY SSF52540 6 415 6.56E-133 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS05470 27fd2d8d69fa5db134e55de90451bbdc 689 Pfam PF12344 Ultra-violet resistance protein B 552 593 1.5E-16 T 22-04-2016 IPR024759 UvrB, YAD/RRR-motif-containing domain L21SP4_RS05470 27fd2d8d69fa5db134e55de90451bbdc 689 Pfam PF02151 UvrB/uvrC motif 622 655 6.0E-10 T 22-04-2016 IPR001943 UVR domain GO:0005515 L21SP4_RS05470 27fd2d8d69fa5db134e55de90451bbdc 689 Pfam PF04851 Type III restriction enzyme, res subunit 18 141 5.7E-8 T 22-04-2016 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 L21SP4_RS05470 27fd2d8d69fa5db134e55de90451bbdc 689 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 7 654 0.0 T 22-04-2016 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 L21SP4_RS05470 27fd2d8d69fa5db134e55de90451bbdc 689 SUPERFAMILY SSF46600 619 656 1.01E-10 T 22-04-2016 IPR001943 UVR domain GO:0005515 L21SP4_RS05470 27fd2d8d69fa5db134e55de90451bbdc 689 Pfam PF00271 Helicase conserved C-terminal domain 432 545 2.5E-18 T 22-04-2016 IPR001650 Helicase, C-terminal L21SP4_RS05470 27fd2d8d69fa5db134e55de90451bbdc 689 PANTHER PTHR24029 1 678 0.0 T 22-04-2016 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 L21SP4_RS05470 27fd2d8d69fa5db134e55de90451bbdc 689 SUPERFAMILY SSF52540 40 84 3.97E-34 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS05470 27fd2d8d69fa5db134e55de90451bbdc 689 Hamap MF_00204 UvrABC system protein B [uvrB]. 5 656 42.607 T 22-04-2016 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 L21SP4_RS05470 27fd2d8d69fa5db134e55de90451bbdc 689 SUPERFAMILY SSF52540 459 577 3.97E-34 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS05470 27fd2d8d69fa5db134e55de90451bbdc 689 SMART SM00487 11 426 1.3E-26 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain L21SP4_RS05470 27fd2d8d69fa5db134e55de90451bbdc 689 Gene3D G3DSA:3.30.2060.10 162 240 2.4E-12 T 22-04-2016 L21SP4_RS05470 27fd2d8d69fa5db134e55de90451bbdc 689 Gene3D G3DSA:4.10.860.10 619 656 2.1E-11 T 22-04-2016 IPR001943 UVR domain GO:0005515 L21SP4_RS05470 27fd2d8d69fa5db134e55de90451bbdc 689 Gene3D G3DSA:3.40.50.300 425 580 8.0E-36 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS10265 421022a92bc5eff6934f9a05975e5cea 342 Gene3D G3DSA:3.30.70.890 189 322 1.2E-43 T 22-04-2016 IPR013750 GHMP kinase, C-terminal domain L21SP4_RS10265 421022a92bc5eff6934f9a05975e5cea 342 PIRSF PIRSF015950 14 335 3.5E-98 T 22-04-2016 IPR005935 Diphosphomevalonate/phosphomevalonate decarboxylase GO:0008299|GO:0016831 KEGG: 00900+4.1.1.33|MetaCyc: PWY-7391|MetaCyc: PWY-922 L21SP4_RS10265 421022a92bc5eff6934f9a05975e5cea 342 PANTHER PTHR10977 8 322 8.8E-101 T 22-04-2016 IPR005935 Diphosphomevalonate/phosphomevalonate decarboxylase GO:0008299|GO:0016831 KEGG: 00900+4.1.1.33|MetaCyc: PWY-7391|MetaCyc: PWY-922 L21SP4_RS10265 421022a92bc5eff6934f9a05975e5cea 342 SUPERFAMILY SSF54211 21 185 2.5E-32 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold L21SP4_RS10265 421022a92bc5eff6934f9a05975e5cea 342 SUPERFAMILY SSF55060 194 322 1.58E-32 T 22-04-2016 IPR013750 GHMP kinase, C-terminal domain L21SP4_RS10265 421022a92bc5eff6934f9a05975e5cea 342 Gene3D G3DSA:3.30.230.10 22 187 2.7E-54 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup L21SP4_RS10265 421022a92bc5eff6934f9a05975e5cea 342 PANTHER PTHR10977:SF3 8 322 8.8E-101 T 22-04-2016 L21SP4_RS10265 421022a92bc5eff6934f9a05975e5cea 342 TIGRFAM TIGR01240 mevDPdecarb: diphosphomevalonate decarboxylase 24 321 2.5E-82 T 22-04-2016 IPR029765 Diphosphomevalonate decarboxylase GO:0004163|GO:0005829|GO:0019287 KEGG: 00900+4.1.1.33|MetaCyc: PWY-7391|MetaCyc: PWY-922 L21SP4_RS10265 421022a92bc5eff6934f9a05975e5cea 342 Pfam PF00288 GHMP kinases N terminal domain 110 167 4.1E-8 T 22-04-2016 IPR006204 GHMP kinase N-terminal domain GO:0005524 L21SP4_RS09000 8412d1361d9d8065af3a7497ca21c76b 244 SUPERFAMILY SSF48317 22 228 3.4E-26 T 22-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase L21SP4_RS09000 8412d1361d9d8065af3a7497ca21c76b 244 Gene3D G3DSA:1.20.144.10 57 228 2.0E-20 T 22-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase L21SP4_RS09000 8412d1361d9d8065af3a7497ca21c76b 244 SMART SM00014 93 223 1.5E-6 T 22-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase L21SP4_RS09000 8412d1361d9d8065af3a7497ca21c76b 244 Pfam PF01569 PAP2 superfamily 98 225 2.5E-18 T 22-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase L21SP4_RS01130 c316e3e53d3488272be664212838c9fe 336 PANTHER PTHR11702:SF31 2 322 1.9E-142 T 22-04-2016 L21SP4_RS01130 c316e3e53d3488272be664212838c9fe 336 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 2 320 6.1E-124 T 22-04-2016 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 L21SP4_RS01130 c316e3e53d3488272be664212838c9fe 336 SUPERFAMILY SSF52540 161 328 3.8E-49 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS01130 c316e3e53d3488272be664212838c9fe 336 PANTHER PTHR11702 2 322 1.9E-142 T 22-04-2016 L21SP4_RS01130 c316e3e53d3488272be664212838c9fe 336 PIRSF PIRSF002401 1 335 5.9E-126 T 22-04-2016 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 L21SP4_RS01130 c316e3e53d3488272be664212838c9fe 336 ProSitePatterns PS00905 GTP1/OBG family signature. 212 225 - T 22-04-2016 IPR006074 GTP1/OBG, conserved site GO:0005525 L21SP4_RS01130 c316e3e53d3488272be664212838c9fe 336 Gene3D G3DSA:3.40.50.300 160 322 1.0E-48 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS01130 c316e3e53d3488272be664212838c9fe 336 Pfam PF01926 50S ribosome-binding GTPase 161 283 3.4E-23 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 L21SP4_RS01130 c316e3e53d3488272be664212838c9fe 336 SUPERFAMILY SSF82051 1 157 1.22E-50 T 22-04-2016 IPR006169 GTP1/OBG domain GO:0005525 L21SP4_RS01130 c316e3e53d3488272be664212838c9fe 336 Hamap MF_01454 GTPase Obg [obg]. 1 327 44.708 T 22-04-2016 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 L21SP4_RS01130 c316e3e53d3488272be664212838c9fe 336 Pfam PF01018 GTP1/OBG 2 157 6.2E-54 T 22-04-2016 IPR006169 GTP1/OBG domain GO:0005525 L21SP4_RS01130 c316e3e53d3488272be664212838c9fe 336 Gene3D G3DSA:2.70.210.12 1 155 7.5E-52 T 22-04-2016 IPR006169 GTP1/OBG domain GO:0005525 L21SP4_RS01130 c316e3e53d3488272be664212838c9fe 336 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 161 181 1.0E-32 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 L21SP4_RS01130 c316e3e53d3488272be664212838c9fe 336 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 210 225 1.0E-32 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 L21SP4_RS01130 c316e3e53d3488272be664212838c9fe 336 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 182 200 1.0E-32 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 L21SP4_RS01130 c316e3e53d3488272be664212838c9fe 336 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 227 245 1.0E-32 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 L21SP4_RS08330 dd4f8c2e09e05214522bcca049f19076 178 Gene3D G3DSA:3.90.930.12 83 176 5.9E-35 T 22-04-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 L21SP4_RS08330 dd4f8c2e09e05214522bcca049f19076 178 SUPERFAMILY SSF56053 83 176 3.01E-34 T 22-04-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 L21SP4_RS08330 dd4f8c2e09e05214522bcca049f19076 178 PANTHER PTHR11655 1 176 2.6E-80 T 22-04-2016 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 L21SP4_RS08330 dd4f8c2e09e05214522bcca049f19076 178 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 176 36.752 T 22-04-2016 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 L21SP4_RS08330 dd4f8c2e09e05214522bcca049f19076 178 PIRSF PIRSF002162 1 177 3.7E-43 T 22-04-2016 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 L21SP4_RS08330 dd4f8c2e09e05214522bcca049f19076 178 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 176 3.9E-71 T 22-04-2016 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 L21SP4_RS08330 dd4f8c2e09e05214522bcca049f19076 178 SUPERFAMILY SSF56053 1 82 2.22E-26 T 22-04-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 L21SP4_RS08330 dd4f8c2e09e05214522bcca049f19076 178 Gene3D G3DSA:3.90.930.12 2 82 1.4E-31 T 22-04-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 L21SP4_RS08330 dd4f8c2e09e05214522bcca049f19076 178 PANTHER PTHR11655:SF14 1 176 2.6E-80 T 22-04-2016 L21SP4_RS08330 dd4f8c2e09e05214522bcca049f19076 178 PRINTS PR00059 Ribosomal protein L6 signature 71 96 3.5E-28 T 22-04-2016 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 L21SP4_RS08330 dd4f8c2e09e05214522bcca049f19076 178 PRINTS PR00059 Ribosomal protein L6 signature 99 115 3.5E-28 T 22-04-2016 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 L21SP4_RS08330 dd4f8c2e09e05214522bcca049f19076 178 PRINTS PR00059 Ribosomal protein L6 signature 141 162 3.5E-28 T 22-04-2016 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 L21SP4_RS08330 dd4f8c2e09e05214522bcca049f19076 178 Pfam PF00347 Ribosomal protein L6 91 164 1.5E-15 T 22-04-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 L21SP4_RS08330 dd4f8c2e09e05214522bcca049f19076 178 Pfam PF00347 Ribosomal protein L6 11 82 6.0E-20 T 22-04-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 L21SP4_RS04975 946ea6d49fe3e6a420728337fa8c7dc9 238 PANTHER PTHR34298 2 195 2.2E-47 T 22-04-2016 L21SP4_RS04975 946ea6d49fe3e6a420728337fa8c7dc9 238 Gene3D G3DSA:1.10.10.10 7 98 3.7E-15 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS04975 946ea6d49fe3e6a420728337fa8c7dc9 238 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 9 189 5.3E-35 T 22-04-2016 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 L21SP4_RS04975 946ea6d49fe3e6a420728337fa8c7dc9 238 Pfam PF04079 Segregation and condensation complex subunit ScpB 13 185 1.1E-45 T 22-04-2016 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 L21SP4_RS04975 946ea6d49fe3e6a420728337fa8c7dc9 238 SUPERFAMILY SSF46785 6 99 1.63E-7 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS04975 946ea6d49fe3e6a420728337fa8c7dc9 238 PANTHER PTHR34298:SF2 2 195 2.2E-47 T 22-04-2016 L21SP4_RS04975 946ea6d49fe3e6a420728337fa8c7dc9 238 Gene3D G3DSA:1.10.10.10 103 177 1.5E-31 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS04975 946ea6d49fe3e6a420728337fa8c7dc9 238 PIRSF PIRSF019345 1 223 2.3E-52 T 22-04-2016 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 L21SP4_RS04975 946ea6d49fe3e6a420728337fa8c7dc9 238 SUPERFAMILY SSF46785 103 177 5.99E-24 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS01860 2fd02dde4a7c7163e3c760afad4943fa 582 SUPERFAMILY SSF54862 78 215 4.1E-36 T 22-04-2016 L21SP4_RS01860 2fd02dde4a7c7163e3c760afad4943fa 582 Pfam PF02906 Iron only hydrogenase large subunit, C-terminal domain 227 514 2.5E-86 T 22-04-2016 IPR004108 Iron hydrogenase, large subunit, C-terminal L21SP4_RS01860 2fd02dde4a7c7163e3c760afad4943fa 582 Pfam PF12838 4Fe-4S dicluster domain 147 205 7.5E-7 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain L21SP4_RS01860 2fd02dde4a7c7163e3c760afad4943fa 582 TIGRFAM TIGR02512 FeFe_hydrog_A: [FeFe] hydrogenase, group A 140 517 8.1E-155 T 22-04-2016 IPR013352 Iron hydrogenase, subset GO:0005506|GO:0008901|GO:0051536|GO:0055114 L21SP4_RS01860 2fd02dde4a7c7163e3c760afad4943fa 582 Gene3D G3DSA:4.10.260.20 521 580 3.5E-26 T 22-04-2016 IPR003149 Iron hydrogenase, small subunit L21SP4_RS01860 2fd02dde4a7c7163e3c760afad4943fa 582 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 85 123 1.1E-17 T 22-04-2016 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 L21SP4_RS01860 2fd02dde4a7c7163e3c760afad4943fa 582 Gene3D G3DSA:3.30.70.20 132 195 4.5E-16 T 22-04-2016 L21SP4_RS01860 2fd02dde4a7c7163e3c760afad4943fa 582 PANTHER PTHR11615 5 581 2.9E-129 T 22-04-2016 L21SP4_RS01860 2fd02dde4a7c7163e3c760afad4943fa 582 SUPERFAMILY SSF54292 5 76 8.76E-19 T 22-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 L21SP4_RS01860 2fd02dde4a7c7163e3c760afad4943fa 582 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 3 77 7.0E-17 T 22-04-2016 L21SP4_RS01860 2fd02dde4a7c7163e3c760afad4943fa 582 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 191 202 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site L21SP4_RS01860 2fd02dde4a7c7163e3c760afad4943fa 582 Pfam PF02256 Iron hydrogenase small subunit 522 577 9.4E-26 T 22-04-2016 IPR003149 Iron hydrogenase, small subunit L21SP4_RS01860 2fd02dde4a7c7163e3c760afad4943fa 582 PANTHER PTHR11615:SF112 5 581 2.9E-129 T 22-04-2016 L21SP4_RS01860 2fd02dde4a7c7163e3c760afad4943fa 582 SUPERFAMILY SSF53920 191 575 6.93E-122 T 22-04-2016 IPR009016 Iron hydrogenase L21SP4_RS01860 2fd02dde4a7c7163e3c760afad4943fa 582 Gene3D G3DSA:3.10.20.30 5 62 2.4E-7 T 22-04-2016 IPR012675 Beta-grasp domain L21SP4_RS01860 2fd02dde4a7c7163e3c760afad4943fa 582 SMART SM00929 85 125 2.7E-17 T 22-04-2016 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 L21SP4_RS01860 2fd02dde4a7c7163e3c760afad4943fa 582 SMART SM00902 519 578 3.0E-28 T 22-04-2016 IPR003149 Iron hydrogenase, small subunit L21SP4_RS01860 2fd02dde4a7c7163e3c760afad4943fa 582 Gene3D G3DSA:3.40.50.1780 301 432 5.2E-72 T 22-04-2016 L21SP4_RS01860 2fd02dde4a7c7163e3c760afad4943fa 582 Gene3D G3DSA:3.40.50.1780 196 249 5.2E-72 T 22-04-2016 L21SP4_RS02630 50d3cda219775acad929e4ae850caf79 485 PANTHER PTHR10342:SF199 170 483 1.7E-116 T 22-04-2016 L21SP4_RS02630 50d3cda219775acad929e4ae850caf79 485 PANTHER PTHR10342:SF199 1 132 1.7E-116 T 22-04-2016 L21SP4_RS02630 50d3cda219775acad929e4ae850caf79 485 Pfam PF00884 Sulfatase 26 381 8.5E-61 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS02630 50d3cda219775acad929e4ae850caf79 485 ProSitePatterns PS00523 Sulfatases signature 1. 73 85 - T 22-04-2016 IPR024607 Sulfatase, conserved site L21SP4_RS02630 50d3cda219775acad929e4ae850caf79 485 ProSitePatterns PS00149 Sulfatases signature 2. 121 131 - T 22-04-2016 IPR024607 Sulfatase, conserved site L21SP4_RS02630 50d3cda219775acad929e4ae850caf79 485 SUPERFAMILY SSF53649 24 137 4.19E-107 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS02630 50d3cda219775acad929e4ae850caf79 485 SUPERFAMILY SSF53649 172 481 4.19E-107 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS02630 50d3cda219775acad929e4ae850caf79 485 Gene3D G3DSA:3.30.1120.10 396 482 2.3E-12 T 22-04-2016 L21SP4_RS02630 50d3cda219775acad929e4ae850caf79 485 Gene3D G3DSA:3.40.720.10 24 136 3.0E-93 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS02630 50d3cda219775acad929e4ae850caf79 485 Gene3D G3DSA:3.40.720.10 171 395 3.0E-93 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS02630 50d3cda219775acad929e4ae850caf79 485 PANTHER PTHR10342 170 483 1.7E-116 T 22-04-2016 L21SP4_RS02630 50d3cda219775acad929e4ae850caf79 485 PANTHER PTHR10342 1 132 1.7E-116 T 22-04-2016 L21SP4_RS00520 b2ac7d827b9fca73f351d42b46ccff66 233 PANTHER PTHR32125 1 225 1.4E-107 T 22-04-2016 L21SP4_RS00520 b2ac7d827b9fca73f351d42b46ccff66 233 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 228 1.2E-95 T 22-04-2016 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 L21SP4_RS00520 b2ac7d827b9fca73f351d42b46ccff66 233 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 233 104.346 T 22-04-2016 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 L21SP4_RS00520 b2ac7d827b9fca73f351d42b46ccff66 233 PANTHER PTHR32125:SF1 1 225 1.4E-107 T 22-04-2016 L21SP4_RS00520 b2ac7d827b9fca73f351d42b46ccff66 233 Gene3D G3DSA:3.40.1280.10 1 157 6.3E-64 T 22-04-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal L21SP4_RS00520 b2ac7d827b9fca73f351d42b46ccff66 233 Gene3D G3DSA:1.10.1270.20 167 226 2.1E-31 T 22-04-2016 IPR023148 tRNA (guanine-N1-)-methyltransferase, C-terminal GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 L21SP4_RS00520 b2ac7d827b9fca73f351d42b46ccff66 233 PIRSF PIRSF000386 1 230 2.0E-99 T 22-04-2016 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 L21SP4_RS00520 b2ac7d827b9fca73f351d42b46ccff66 233 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 22 218 4.6E-69 T 22-04-2016 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 L21SP4_RS00520 b2ac7d827b9fca73f351d42b46ccff66 233 SUPERFAMILY SSF75217 1 226 9.16E-96 T 22-04-2016 IPR029028 Alpha/beta knot methyltransferases L21SP4_RS04865 0291b35239be0352608d558f362078a7 363 Gene3D G3DSA:3.20.20.100 1 271 3.3E-34 T 22-04-2016 IPR023210 NADP-dependent oxidoreductase domain L21SP4_RS04865 0291b35239be0352608d558f362078a7 363 Gene3D G3DSA:1.10.1060.10 272 355 7.1E-11 T 22-04-2016 L21SP4_RS04865 0291b35239be0352608d558f362078a7 363 Pfam PF13534 4Fe-4S dicluster domain 279 347 5.8E-10 T 22-04-2016 L21SP4_RS04865 0291b35239be0352608d558f362078a7 363 SUPERFAMILY SSF51430 1 298 1.15E-43 T 22-04-2016 IPR023210 NADP-dependent oxidoreductase domain L21SP4_RS04865 0291b35239be0352608d558f362078a7 363 PANTHER PTHR11732:SF150 1 297 2.9E-41 T 22-04-2016 L21SP4_RS04865 0291b35239be0352608d558f362078a7 363 Pfam PF00248 Aldo/keto reductase family 28 270 1.8E-19 T 22-04-2016 IPR023210 NADP-dependent oxidoreductase domain L21SP4_RS04865 0291b35239be0352608d558f362078a7 363 PANTHER PTHR11732 1 297 2.9E-41 T 22-04-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta L21SP4_RS04865 0291b35239be0352608d558f362078a7 363 SUPERFAMILY SSF46548 275 353 1.74E-11 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 L21SP4_RS08535 b533152e2963911bef487de4336d68cb 148 Pfam PF08843 Nucleotidyl transferase AbiEii toxin, Type IV TA system 22 78 6.1E-5 T 22-04-2016 IPR014942 Nucleotidyl transferase AbiEii toxin, Type IV TA system L21SP4_RS08535 b533152e2963911bef487de4336d68cb 148 SUPERFAMILY SSF81301 5 146 4.9E-27 T 22-04-2016 L21SP4_RS04985 891e867f6891d1a932a10c025fb3fe61 365 PANTHER PTHR11751:SF347 20 365 1.5E-90 T 22-04-2016 L21SP4_RS04985 891e867f6891d1a932a10c025fb3fe61 365 SUPERFAMILY SSF53383 14 362 3.4E-82 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase L21SP4_RS04985 891e867f6891d1a932a10c025fb3fe61 365 Gene3D G3DSA:3.90.1150.10 268 363 1.2E-24 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 L21SP4_RS04985 891e867f6891d1a932a10c025fb3fe61 365 Gene3D G3DSA:3.40.640.10 48 267 6.6E-66 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 L21SP4_RS04985 891e867f6891d1a932a10c025fb3fe61 365 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 4 364 56.885 T 22-04-2016 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9|UniPathway: UPA00031 L21SP4_RS04985 891e867f6891d1a932a10c025fb3fe61 365 PANTHER PTHR11751 20 365 1.5E-90 T 22-04-2016 L21SP4_RS04985 891e867f6891d1a932a10c025fb3fe61 365 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 225 234 - T 22-04-2016 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 L21SP4_RS04985 891e867f6891d1a932a10c025fb3fe61 365 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 8 363 4.6E-95 T 22-04-2016 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9|UniPathway: UPA00031 L21SP4_RS04985 891e867f6891d1a932a10c025fb3fe61 365 Pfam PF00155 Aminotransferase class I and II 35 360 3.9E-49 T 22-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 L21SP4_RS02375 53b81e4b6edddcb3e87dabeae1f7c668 171 Gene3D G3DSA:1.10.287.950 30 94 4.3E-4 T 22-04-2016 L21SP4_RS02375 53b81e4b6edddcb3e87dabeae1f7c668 171 Gene3D G3DSA:1.10.287.950 95 164 3.8E-4 T 22-04-2016 L21SP4_RS02375 53b81e4b6edddcb3e87dabeae1f7c668 171 SUPERFAMILY SSF57997 28 161 1.96E-10 T 22-04-2016 L21SP4_RS02375 53b81e4b6edddcb3e87dabeae1f7c668 171 Pfam PF09728 Myosin-like coiled-coil protein 31 164 3.1E-7 T 22-04-2016 IPR026183 Taxilin family GO:0019905 L21SP4_RS02375 53b81e4b6edddcb3e87dabeae1f7c668 171 PANTHER PTHR13140 35 168 4.1E-13 T 22-04-2016 L21SP4_RS02955 c5f7ab4351d567383c431fc76d173317 923 Pfam PF00476 DNA polymerase family A 544 920 1.6E-143 T 22-04-2016 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 L21SP4_RS02955 c5f7ab4351d567383c431fc76d173317 923 Gene3D G3DSA:3.30.70.370 814 923 3.3E-59 T 22-04-2016 L21SP4_RS02955 c5f7ab4351d567383c431fc76d173317 923 Gene3D G3DSA:3.30.70.370 657 706 3.3E-59 T 22-04-2016 L21SP4_RS02955 c5f7ab4351d567383c431fc76d173317 923 SMART SM00279 176 211 2.7E-13 T 22-04-2016 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 L21SP4_RS02955 c5f7ab4351d567383c431fc76d173317 923 Gene3D G3DSA:3.40.50.1010 3 188 9.5E-64 T 22-04-2016 IPR029060 PIN domain-like L21SP4_RS02955 c5f7ab4351d567383c431fc76d173317 923 SUPERFAMILY SSF47807 176 287 2.69E-35 T 22-04-2016 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 L21SP4_RS02955 c5f7ab4351d567383c431fc76d173317 923 ProSitePatterns PS00447 DNA polymerase family A signature. 749 768 - T 22-04-2016 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 L21SP4_RS02955 c5f7ab4351d567383c431fc76d173317 923 PRINTS PR00868 DNA-polymerase family A (pol I) signature 840 856 1.2E-72 T 22-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 L21SP4_RS02955 c5f7ab4351d567383c431fc76d173317 923 PRINTS PR00868 DNA-polymerase family A (pol I) signature 870 883 1.2E-72 T 22-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 L21SP4_RS02955 c5f7ab4351d567383c431fc76d173317 923 PRINTS PR00868 DNA-polymerase family A (pol I) signature 725 738 1.2E-72 T 22-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 L21SP4_RS02955 c5f7ab4351d567383c431fc76d173317 923 PRINTS PR00868 DNA-polymerase family A (pol I) signature 672 687 1.2E-72 T 22-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 L21SP4_RS02955 c5f7ab4351d567383c431fc76d173317 923 PRINTS PR00868 DNA-polymerase family A (pol I) signature 786 797 1.2E-72 T 22-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 L21SP4_RS02955 c5f7ab4351d567383c431fc76d173317 923 PRINTS PR00868 DNA-polymerase family A (pol I) signature 649 671 1.2E-72 T 22-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 L21SP4_RS02955 c5f7ab4351d567383c431fc76d173317 923 PRINTS PR00868 DNA-polymerase family A (pol I) signature 695 718 1.2E-72 T 22-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 L21SP4_RS02955 c5f7ab4351d567383c431fc76d173317 923 PRINTS PR00868 DNA-polymerase family A (pol I) signature 808 819 1.2E-72 T 22-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 L21SP4_RS02955 c5f7ab4351d567383c431fc76d173317 923 PRINTS PR00868 DNA-polymerase family A (pol I) signature 749 774 1.2E-72 T 22-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 L21SP4_RS02955 c5f7ab4351d567383c431fc76d173317 923 SUPERFAMILY SSF56672 515 923 6.23E-146 T 22-04-2016 L21SP4_RS02955 c5f7ab4351d567383c431fc76d173317 923 SMART SM00482 680 887 2.7E-103 T 22-04-2016 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 L21SP4_RS02955 c5f7ab4351d567383c431fc76d173317 923 Gene3D G3DSA:1.20.1060.10 536 656 5.9E-36 T 22-04-2016 L21SP4_RS02955 c5f7ab4351d567383c431fc76d173317 923 Gene3D G3DSA:1.10.150.20 189 249 4.9E-30 T 22-04-2016 L21SP4_RS02955 c5f7ab4351d567383c431fc76d173317 923 TIGRFAM TIGR00593 pola: DNA polymerase I 5 923 3.4E-291 T 22-04-2016 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 L21SP4_RS02955 c5f7ab4351d567383c431fc76d173317 923 Gene3D G3DSA:3.30.420.10 329 535 1.8E-71 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS02955 c5f7ab4351d567383c431fc76d173317 923 SUPERFAMILY SSF53098 330 512 6.08E-47 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS02955 c5f7ab4351d567383c431fc76d173317 923 Gene3D G3DSA:1.10.150.20 707 813 1.7E-32 T 22-04-2016 L21SP4_RS02955 c5f7ab4351d567383c431fc76d173317 923 PANTHER PTHR10133:SF27 315 922 0.0 T 22-04-2016 L21SP4_RS02955 c5f7ab4351d567383c431fc76d173317 923 PANTHER PTHR10133:SF27 1 284 0.0 T 22-04-2016 L21SP4_RS02955 c5f7ab4351d567383c431fc76d173317 923 SMART SM00475 3 264 5.4E-128 T 22-04-2016 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 L21SP4_RS02955 c5f7ab4351d567383c431fc76d173317 923 Pfam PF01612 3'-5' exonuclease 332 511 5.2E-33 T 22-04-2016 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 L21SP4_RS02955 c5f7ab4351d567383c431fc76d173317 923 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 4 172 9.9E-51 T 22-04-2016 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 L21SP4_RS02955 c5f7ab4351d567383c431fc76d173317 923 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 176 268 1.3E-33 T 22-04-2016 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 L21SP4_RS02955 c5f7ab4351d567383c431fc76d173317 923 SUPERFAMILY SSF88723 3 154 3.27E-50 T 22-04-2016 IPR029060 PIN domain-like L21SP4_RS02955 c5f7ab4351d567383c431fc76d173317 923 SMART SM00474 332 511 4.7E-32 T 22-04-2016 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 L21SP4_RS02955 c5f7ab4351d567383c431fc76d173317 923 PANTHER PTHR10133 315 922 0.0 T 22-04-2016 L21SP4_RS02955 c5f7ab4351d567383c431fc76d173317 923 PANTHER PTHR10133 1 284 0.0 T 22-04-2016 L21SP4_RS07105 7a09d83d0f9b30287ba2eb01c76b87fa 196 PRINTS PR00127 Clp protease catalytic subunit P signature 167 186 1.4E-54 T 22-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 L21SP4_RS07105 7a09d83d0f9b30287ba2eb01c76b87fa 196 PRINTS PR00127 Clp protease catalytic subunit P signature 110 129 1.4E-54 T 22-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 L21SP4_RS07105 7a09d83d0f9b30287ba2eb01c76b87fa 196 PRINTS PR00127 Clp protease catalytic subunit P signature 18 33 1.4E-54 T 22-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 L21SP4_RS07105 7a09d83d0f9b30287ba2eb01c76b87fa 196 PRINTS PR00127 Clp protease catalytic subunit P signature 58 78 1.4E-54 T 22-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 L21SP4_RS07105 7a09d83d0f9b30287ba2eb01c76b87fa 196 PRINTS PR00127 Clp protease catalytic subunit P signature 89 106 1.4E-54 T 22-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 L21SP4_RS07105 7a09d83d0f9b30287ba2eb01c76b87fa 196 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 89 100 - T 22-04-2016 IPR018215 ClpP, Ser active site L21SP4_RS07105 7a09d83d0f9b30287ba2eb01c76b87fa 196 Pfam PF00574 Clp protease 12 191 3.7E-88 T 22-04-2016 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA L21SP4_RS07105 7a09d83d0f9b30287ba2eb01c76b87fa 196 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 2 192 44.444 T 22-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 L21SP4_RS07105 7a09d83d0f9b30287ba2eb01c76b87fa 196 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 111 124 - T 22-04-2016 IPR033135 ClpP, histidine active site L21SP4_RS07105 7a09d83d0f9b30287ba2eb01c76b87fa 196 Gene3D G3DSA:3.90.226.10 2 191 1.2E-89 T 22-04-2016 IPR029045 ClpP/crotonase-like domain L21SP4_RS07105 7a09d83d0f9b30287ba2eb01c76b87fa 196 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 2 190 6.7E-101 T 22-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 L21SP4_RS07105 7a09d83d0f9b30287ba2eb01c76b87fa 196 PANTHER PTHR10381 1 190 2.5E-134 T 22-04-2016 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA L21SP4_RS07105 7a09d83d0f9b30287ba2eb01c76b87fa 196 SUPERFAMILY SSF52096 9 191 4.56E-74 T 22-04-2016 IPR029045 ClpP/crotonase-like domain L21SP4_RS11680 4259570f9a93be5b00d65985a974bf58 419 Gene3D G3DSA:2.120.10.30 103 271 1.9E-7 T 22-04-2016 IPR011042 Six-bladed beta-propeller, TolB-like L21SP4_RS11680 4259570f9a93be5b00d65985a974bf58 419 SUPERFAMILY SSF63829 55 68 1.96E-7 T 22-04-2016 L21SP4_RS11680 4259570f9a93be5b00d65985a974bf58 419 SUPERFAMILY SSF63829 102 271 1.96E-7 T 22-04-2016 L21SP4_RS11680 4259570f9a93be5b00d65985a974bf58 419 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 316 339 2.0E-4 T 22-04-2016 IPR013424 PEP-CTERM protein-sorting domain L21SP4_RS05540 073e911a5cacaeb99cb8fa9dad719235 445 SUPERFAMILY SSF55347 176 204 5.89E-19 T 22-04-2016 L21SP4_RS05540 073e911a5cacaeb99cb8fa9dad719235 445 SUPERFAMILY SSF55347 256 398 5.89E-19 T 22-04-2016 L21SP4_RS05540 073e911a5cacaeb99cb8fa9dad719235 445 SUPERFAMILY SSF51735 30 197 1.8E-40 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS05540 073e911a5cacaeb99cb8fa9dad719235 445 Gene3D G3DSA:3.40.50.720 37 187 3.3E-40 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS05540 073e911a5cacaeb99cb8fa9dad719235 445 PANTHER PTHR22604:SF122 6 204 2.5E-87 T 22-04-2016 L21SP4_RS05540 073e911a5cacaeb99cb8fa9dad719235 445 PANTHER PTHR22604:SF122 228 428 2.5E-87 T 22-04-2016 L21SP4_RS05540 073e911a5cacaeb99cb8fa9dad719235 445 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 44 166 2.0E-15 T 22-04-2016 IPR000683 Oxidoreductase, N-terminal GO:0016491 L21SP4_RS05540 073e911a5cacaeb99cb8fa9dad719235 445 Gene3D G3DSA:3.30.360.10 188 210 7.1E-21 T 22-04-2016 L21SP4_RS05540 073e911a5cacaeb99cb8fa9dad719235 445 Gene3D G3DSA:3.30.360.10 255 404 7.1E-21 T 22-04-2016 L21SP4_RS05540 073e911a5cacaeb99cb8fa9dad719235 445 PANTHER PTHR22604 6 204 2.5E-87 T 22-04-2016 L21SP4_RS05540 073e911a5cacaeb99cb8fa9dad719235 445 PANTHER PTHR22604 228 428 2.5E-87 T 22-04-2016 L21SP4_RS00005 3a025f49b258cbd7c0810b72e177380e 453 ProSitePatterns PS01008 DnaA protein signature. 405 423 - T 22-04-2016 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 L21SP4_RS00005 3a025f49b258cbd7c0810b72e177380e 453 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 7 445 31.185 T 22-04-2016 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 L21SP4_RS00005 3a025f49b258cbd7c0810b72e177380e 453 Pfam PF00308 Bacterial dnaA protein 112 328 5.8E-90 T 22-04-2016 IPR013317 Chromosomal replication initiator protein DnaA L21SP4_RS00005 3a025f49b258cbd7c0810b72e177380e 453 Gene3D G3DSA:3.40.50.300 96 275 1.1E-60 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS00005 3a025f49b258cbd7c0810b72e177380e 453 SUPERFAMILY SSF48295 342 444 6.8E-31 T 22-04-2016 IPR010921 Trp repressor/replication initiator GO:0043565 L21SP4_RS00005 3a025f49b258cbd7c0810b72e177380e 453 SMART SM00760 355 423 7.1E-32 T 22-04-2016 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 L21SP4_RS00005 3a025f49b258cbd7c0810b72e177380e 453 SMART SM00382 144 274 8.2E-13 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS00005 3a025f49b258cbd7c0810b72e177380e 453 Gene3D G3DSA:1.10.1750.10 344 445 4.2E-34 T 22-04-2016 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 L21SP4_RS00005 3a025f49b258cbd7c0810b72e177380e 453 PANTHER PTHR30050:SF2 7 447 6.6E-189 T 22-04-2016 L21SP4_RS00005 3a025f49b258cbd7c0810b72e177380e 453 SUPERFAMILY SSF52540 111 323 1.19E-44 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS00005 3a025f49b258cbd7c0810b72e177380e 453 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 10 444 3.3E-158 T 22-04-2016 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 L21SP4_RS00005 3a025f49b258cbd7c0810b72e177380e 453 Gene3D G3DSA:1.10.8.60 278 333 3.7E-18 T 22-04-2016 L21SP4_RS00005 3a025f49b258cbd7c0810b72e177380e 453 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 356 423 1.1E-25 T 22-04-2016 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 L21SP4_RS00005 3a025f49b258cbd7c0810b72e177380e 453 Pfam PF11638 DnaA N-terminal domain 9 69 1.7E-12 T 22-04-2016 IPR024633 DnaA N-terminal domain L21SP4_RS00005 3a025f49b258cbd7c0810b72e177380e 453 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 209 223 4.1E-42 T 22-04-2016 IPR020591 Chromosomal replication control, initiator DnaA-like L21SP4_RS00005 3a025f49b258cbd7c0810b72e177380e 453 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 243 270 4.1E-42 T 22-04-2016 IPR020591 Chromosomal replication control, initiator DnaA-like L21SP4_RS00005 3a025f49b258cbd7c0810b72e177380e 453 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 404 423 4.1E-42 T 22-04-2016 IPR020591 Chromosomal replication control, initiator DnaA-like L21SP4_RS00005 3a025f49b258cbd7c0810b72e177380e 453 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 145 165 4.1E-42 T 22-04-2016 IPR020591 Chromosomal replication control, initiator DnaA-like L21SP4_RS00005 3a025f49b258cbd7c0810b72e177380e 453 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 177 191 4.1E-42 T 22-04-2016 IPR020591 Chromosomal replication control, initiator DnaA-like L21SP4_RS00005 3a025f49b258cbd7c0810b72e177380e 453 PANTHER PTHR30050 7 447 6.6E-189 T 22-04-2016 L21SP4_RS09100 6c18b53552eb5105f8900a60dd38e8dd 343 PANTHER PTHR22976 1 340 2.7E-100 T 22-04-2016 L21SP4_RS09100 6c18b53552eb5105f8900a60dd38e8dd 343 Pfam PF04055 Radical SAM superfamily 43 202 1.1E-17 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 L21SP4_RS09100 6c18b53552eb5105f8900a60dd38e8dd 343 SUPERFAMILY SSF102114 7 302 2.88E-54 T 22-04-2016 L21SP4_RS09100 6c18b53552eb5105f8900a60dd38e8dd 343 SMART SM00729 39 245 4.5E-19 T 22-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 L21SP4_RS09100 6c18b53552eb5105f8900a60dd38e8dd 343 PIRSF PIRSF004762 1 337 1.3E-61 T 22-04-2016 IPR005244 FO synthase, subunit 2-like GO:0016765|GO:0051188|GO:0051539 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198|UniPathway: UPA00072 L21SP4_RS09100 6c18b53552eb5105f8900a60dd38e8dd 343 Gene3D G3DSA:3.20.20.70 14 312 1.5E-74 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP4_RS09100 6c18b53552eb5105f8900a60dd38e8dd 343 PANTHER PTHR22976:SF28 1 340 2.7E-100 T 22-04-2016 L21SP4_RS09100 6c18b53552eb5105f8900a60dd38e8dd 343 TIGRFAM TIGR03956 rSAM_HydE: [FeFe] hydrogenase H-cluster radical SAM maturase HydE 8 340 9.5E-88 T 22-04-2016 IPR024021 [FeFe]-hydrogenase maturation HydE, radical SAM L21SP4_RS08875 6a22d9b273b335690f56d3201148d5aa 511 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 406 503 8.8E-32 T 22-04-2016 IPR025158 Mg chelatase-related protein, C-terminal domain L21SP4_RS08875 6a22d9b273b335690f56d3201148d5aa 511 PANTHER PTHR32039 1 507 3.6E-238 T 22-04-2016 L21SP4_RS08875 6a22d9b273b335690f56d3201148d5aa 511 SUPERFAMILY SSF54211 6 168 2.31E-34 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold L21SP4_RS08875 6a22d9b273b335690f56d3201148d5aa 511 TIGRFAM TIGR00368 TIGR00368: Mg chelatase-like protein 6 503 1.4E-183 T 22-04-2016 IPR004482 Mg chelatase-related protein L21SP4_RS08875 6a22d9b273b335690f56d3201148d5aa 511 SUPERFAMILY SSF52540 193 507 2.85E-48 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS08875 6a22d9b273b335690f56d3201148d5aa 511 SMART SM00382 213 396 1.1E-6 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS08875 6a22d9b273b335690f56d3201148d5aa 511 Pfam PF01078 Magnesium chelatase, subunit ChlI 193 399 3.2E-97 T 22-04-2016 IPR000523 Magnesium chelatase ChlI domain L21SP4_RS08875 6a22d9b273b335690f56d3201148d5aa 511 Pfam PF13541 Subunit ChlI of Mg-chelatase 20 143 1.8E-37 T 22-04-2016 L21SP4_RS08875 6a22d9b273b335690f56d3201148d5aa 511 Gene3D G3DSA:3.40.50.300 193 393 7.8E-52 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS08875 6a22d9b273b335690f56d3201148d5aa 511 Gene3D G3DSA:3.30.230.10 9 168 1.4E-29 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup L21SP4_RS08875 6a22d9b273b335690f56d3201148d5aa 511 PANTHER PTHR32039:SF7 1 507 3.6E-238 T 22-04-2016 IPR004482 Mg chelatase-related protein L21SP4_RS08875 6a22d9b273b335690f56d3201148d5aa 511 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 321 334 3.3E-5 T 22-04-2016 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006260 L21SP4_RS08875 6a22d9b273b335690f56d3201148d5aa 511 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 212 227 3.3E-5 T 22-04-2016 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006260 L21SP4_RS08875 6a22d9b273b335690f56d3201148d5aa 511 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 293 307 3.3E-5 T 22-04-2016 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006260 L21SP4_RS04320 3cfb0ac4f902089fffd59825f69f3205 1085 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 426 545 2.0E-37 T 22-04-2016 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 L21SP4_RS04320 3cfb0ac4f902089fffd59825f69f3205 1085 SMART SM01096 422 546 7.0E-44 T 22-04-2016 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 L21SP4_RS04320 3cfb0ac4f902089fffd59825f69f3205 1085 Gene3D G3DSA:3.40.50.20 536 662 1.4E-58 T 22-04-2016 IPR016185 Pre-ATP-grasp domain L21SP4_RS04320 3cfb0ac4f902089fffd59825f69f3205 1085 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 129 335 4.6E-69 T 22-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 L21SP4_RS04320 3cfb0ac4f902089fffd59825f69f3205 1085 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 673 875 5.9E-38 T 22-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 L21SP4_RS04320 3cfb0ac4f902089fffd59825f69f3205 1085 Gene3D G3DSA:3.40.50.20 4 108 1.6E-43 T 22-04-2016 IPR016185 Pre-ATP-grasp domain L21SP4_RS04320 3cfb0ac4f902089fffd59825f69f3205 1085 SUPERFAMILY SSF52440 555 674 1.18E-49 T 22-04-2016 IPR016185 Pre-ATP-grasp domain L21SP4_RS04320 3cfb0ac4f902089fffd59825f69f3205 1085 SUPERFAMILY SSF56059 673 934 2.47E-100 T 22-04-2016 L21SP4_RS04320 3cfb0ac4f902089fffd59825f69f3205 1085 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1054 0.0 T 22-04-2016 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 L21SP4_RS04320 3cfb0ac4f902089fffd59825f69f3205 1085 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1064 12.765 T 22-04-2016 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 L21SP4_RS04320 3cfb0ac4f902089fffd59825f69f3205 1085 SUPERFAMILY SSF56059 129 401 2.12E-103 T 22-04-2016 L21SP4_RS04320 3cfb0ac4f902089fffd59825f69f3205 1085 SUPERFAMILY SSF52335 936 1073 5.49E-33 T 22-04-2016 IPR011607 Methylglyoxal synthase-like domain L21SP4_RS04320 3cfb0ac4f902089fffd59825f69f3205 1085 Gene3D G3DSA:3.30.470.20 748 935 2.4E-73 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 L21SP4_RS04320 3cfb0ac4f902089fffd59825f69f3205 1085 Gene3D G3DSA:3.30.470.20 201 400 3.3E-74 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 L21SP4_RS04320 3cfb0ac4f902089fffd59825f69f3205 1085 Pfam PF02142 MGS-like domain 958 1043 4.9E-14 T 22-04-2016 IPR011607 Methylglyoxal synthase-like domain L21SP4_RS04320 3cfb0ac4f902089fffd59825f69f3205 1085 SMART SM00851 956 1043 7.6E-19 T 22-04-2016 IPR011607 Methylglyoxal synthase-like domain L21SP4_RS04320 3cfb0ac4f902089fffd59825f69f3205 1085 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 838 845 - T 22-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 L21SP4_RS04320 3cfb0ac4f902089fffd59825f69f3205 1085 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 298 305 - T 22-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 L21SP4_RS04320 3cfb0ac4f902089fffd59825f69f3205 1085 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 165 179 - T 22-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 L21SP4_RS04320 3cfb0ac4f902089fffd59825f69f3205 1085 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 709 723 - T 22-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 L21SP4_RS04320 3cfb0ac4f902089fffd59825f69f3205 1085 SUPERFAMILY SSF48108 396 549 4.71E-42 T 22-04-2016 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 L21SP4_RS04320 3cfb0ac4f902089fffd59825f69f3205 1085 SUPERFAMILY SSF52440 1 127 3.88E-49 T 22-04-2016 IPR016185 Pre-ATP-grasp domain L21SP4_RS04320 3cfb0ac4f902089fffd59825f69f3205 1085 Gene3D G3DSA:1.10.1030.10 401 535 5.0E-43 T 22-04-2016 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 L21SP4_RS04320 3cfb0ac4f902089fffd59825f69f3205 1085 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1071 13.393 T 22-04-2016 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 L21SP4_RS04320 3cfb0ac4f902089fffd59825f69f3205 1085 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 240 257 2.7E-65 T 22-04-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 L21SP4_RS04320 3cfb0ac4f902089fffd59825f69f3205 1085 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 380 398 2.7E-65 T 22-04-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 L21SP4_RS04320 3cfb0ac4f902089fffd59825f69f3205 1085 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 2.7E-65 T 22-04-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 L21SP4_RS04320 3cfb0ac4f902089fffd59825f69f3205 1085 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 169 181 2.7E-65 T 22-04-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 L21SP4_RS04320 3cfb0ac4f902089fffd59825f69f3205 1085 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 205 224 2.7E-65 T 22-04-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 L21SP4_RS04320 3cfb0ac4f902089fffd59825f69f3205 1085 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 298 327 2.7E-65 T 22-04-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 L21SP4_RS04320 3cfb0ac4f902089fffd59825f69f3205 1085 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 2.7E-65 T 22-04-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 L21SP4_RS04320 3cfb0ac4f902089fffd59825f69f3205 1085 PANTHER PTHR11405 1 1074 0.0 T 22-04-2016 L21SP4_RS04320 3cfb0ac4f902089fffd59825f69f3205 1085 Gene3D G3DSA:3.40.50.1380 938 1073 4.5E-32 T 22-04-2016 IPR011607 Methylglyoxal synthase-like domain L21SP4_RS04320 3cfb0ac4f902089fffd59825f69f3205 1085 Gene3D G3DSA:3.30.1490.20 142 200 2.8E-19 T 22-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 L21SP4_RS04320 3cfb0ac4f902089fffd59825f69f3205 1085 Gene3D G3DSA:3.30.1490.20 686 747 2.6E-25 T 22-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 L21SP4_RS04320 3cfb0ac4f902089fffd59825f69f3205 1085 PANTHER PTHR11405:SF5 1 1074 0.0 T 22-04-2016 L21SP4_RS10050 7398bb19a8f1e630ed908f67a9051b18 86 SUPERFAMILY SSF47598 8 46 2.22E-6 T 22-04-2016 IPR010985 Ribbon-helix-helix GO:0006355 L21SP4_RS10050 7398bb19a8f1e630ed908f67a9051b18 86 Gene3D G3DSA:1.10.1220.10 8 45 2.0E-4 T 22-04-2016 IPR013321 Arc-type ribbon-helix-helix GO:0006355 L21SP4_RS06915 166a771d0649d9eb0ec4b313df689a39 659 Gene3D G3DSA:1.20.1270.10 534 605 5.0E-22 T 22-04-2016 IPR029048 Heat shock protein 70kD, C-terminal domain L21SP4_RS06915 166a771d0649d9eb0ec4b313df689a39 659 PANTHER PTHR19375 10 656 0.0 T 22-04-2016 L21SP4_RS06915 166a771d0649d9eb0ec4b313df689a39 659 Gene3D G3DSA:3.30.420.40 199 231 2.9E-35 T 22-04-2016 L21SP4_RS06915 166a771d0649d9eb0ec4b313df689a39 659 Gene3D G3DSA:3.30.420.40 321 363 2.9E-35 T 22-04-2016 L21SP4_RS06915 166a771d0649d9eb0ec4b313df689a39 659 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 198 211 - T 22-04-2016 IPR018181 Heat shock protein 70, conserved site L21SP4_RS06915 166a771d0649d9eb0ec4b313df689a39 659 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 16 23 - T 22-04-2016 IPR018181 Heat shock protein 70, conserved site L21SP4_RS06915 166a771d0649d9eb0ec4b313df689a39 659 PANTHER PTHR19375:SF173 10 656 0.0 T 22-04-2016 L21SP4_RS06915 166a771d0649d9eb0ec4b313df689a39 659 SUPERFAMILY SSF53067 13 191 3.24E-64 T 22-04-2016 L21SP4_RS06915 166a771d0649d9eb0ec4b313df689a39 659 PRINTS PR00301 70kDa heat shock protein signature 471 487 2.2E-80 T 22-04-2016 IPR013126 Heat shock protein 70 family L21SP4_RS06915 166a771d0649d9eb0ec4b313df689a39 659 PRINTS PR00301 70kDa heat shock protein signature 40 52 2.2E-80 T 22-04-2016 IPR013126 Heat shock protein 70 family L21SP4_RS06915 166a771d0649d9eb0ec4b313df689a39 659 PRINTS PR00301 70kDa heat shock protein signature 145 165 2.2E-80 T 22-04-2016 IPR013126 Heat shock protein 70 family L21SP4_RS06915 166a771d0649d9eb0ec4b313df689a39 659 PRINTS PR00301 70kDa heat shock protein signature 390 409 2.2E-80 T 22-04-2016 IPR013126 Heat shock protein 70 family L21SP4_RS06915 166a771d0649d9eb0ec4b313df689a39 659 PRINTS PR00301 70kDa heat shock protein signature 204 214 2.2E-80 T 22-04-2016 IPR013126 Heat shock protein 70 family L21SP4_RS06915 166a771d0649d9eb0ec4b313df689a39 659 PRINTS PR00301 70kDa heat shock protein signature 336 352 2.2E-80 T 22-04-2016 IPR013126 Heat shock protein 70 family L21SP4_RS06915 166a771d0649d9eb0ec4b313df689a39 659 PRINTS PR00301 70kDa heat shock protein signature 63 71 2.2E-80 T 22-04-2016 IPR013126 Heat shock protein 70 family L21SP4_RS06915 166a771d0649d9eb0ec4b313df689a39 659 PRINTS PR00301 70kDa heat shock protein signature 367 387 2.2E-80 T 22-04-2016 IPR013126 Heat shock protein 70 family L21SP4_RS06915 166a771d0649d9eb0ec4b313df689a39 659 PRINTS PR00301 70kDa heat shock protein signature 12 25 2.2E-80 T 22-04-2016 IPR013126 Heat shock protein 70 family L21SP4_RS06915 166a771d0649d9eb0ec4b313df689a39 659 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 339 353 - T 22-04-2016 IPR018181 Heat shock protein 70, conserved site L21SP4_RS06915 166a771d0649d9eb0ec4b313df689a39 659 Gene3D G3DSA:2.60.34.10 392 533 2.5E-73 T 22-04-2016 IPR029047 Heat shock protein 70kD, peptide-binding domain L21SP4_RS06915 166a771d0649d9eb0ec4b313df689a39 659 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 10 652 37.813 T 22-04-2016 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 L21SP4_RS06915 166a771d0649d9eb0ec4b313df689a39 659 Gene3D G3DSA:3.30.30.30 62 113 1.1E-25 T 22-04-2016 L21SP4_RS06915 166a771d0649d9eb0ec4b313df689a39 659 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 12 606 5.6E-302 T 22-04-2016 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 L21SP4_RS06915 166a771d0649d9eb0ec4b313df689a39 659 SUPERFAMILY SSF53067 193 384 9.72E-64 T 22-04-2016 L21SP4_RS06915 166a771d0649d9eb0ec4b313df689a39 659 Gene3D G3DSA:3.90.640.10 232 315 1.5E-28 T 22-04-2016 L21SP4_RS06915 166a771d0649d9eb0ec4b313df689a39 659 SUPERFAMILY SSF100920 386 542 3.92E-63 T 22-04-2016 IPR029047 Heat shock protein 70kD, peptide-binding domain L21SP4_RS06915 166a771d0649d9eb0ec4b313df689a39 659 Pfam PF00012 Hsp70 protein 13 606 2.4E-264 T 22-04-2016 IPR013126 Heat shock protein 70 family L21SP4_RS06915 166a771d0649d9eb0ec4b313df689a39 659 Gene3D G3DSA:3.30.420.40 13 61 2.4E-64 T 22-04-2016 L21SP4_RS06915 166a771d0649d9eb0ec4b313df689a39 659 Gene3D G3DSA:3.30.420.40 126 198 2.4E-64 T 22-04-2016 L21SP4_RS02925 fb46c76799963d8af54700892b4e9f07 260 Gene3D G3DSA:3.20.20.140 1 257 2.1E-81 T 22-04-2016 L21SP4_RS02925 fb46c76799963d8af54700892b4e9f07 260 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 1 256 7.0E-73 T 22-04-2016 IPR015991 Uncharacterised deoxyribonuclease TatD-type GO:0004536 L21SP4_RS02925 fb46c76799963d8af54700892b4e9f07 260 ProSitePatterns PS01090 TatD deoxyribonuclease family signature 2. 123 133 - T 22-04-2016 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 L21SP4_RS02925 fb46c76799963d8af54700892b4e9f07 260 PANTHER PTHR10060:SF20 1 259 7.0E-99 T 22-04-2016 L21SP4_RS02925 fb46c76799963d8af54700892b4e9f07 260 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 192 208 - T 22-04-2016 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 L21SP4_RS02925 fb46c76799963d8af54700892b4e9f07 260 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 1 9 - T 22-04-2016 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 L21SP4_RS02925 fb46c76799963d8af54700892b4e9f07 260 PANTHER PTHR10060 1 259 7.0E-99 T 22-04-2016 IPR001130 TatD family GO:0016788 L21SP4_RS02925 fb46c76799963d8af54700892b4e9f07 260 Pfam PF01026 TatD related DNase 2 256 8.7E-68 T 22-04-2016 IPR001130 TatD family GO:0016788 L21SP4_RS02925 fb46c76799963d8af54700892b4e9f07 260 PIRSF PIRSF005902 1 259 3.7E-69 T 22-04-2016 IPR001130 TatD family GO:0016788 L21SP4_RS02925 fb46c76799963d8af54700892b4e9f07 260 SUPERFAMILY SSF51556 1 257 2.99E-74 T 22-04-2016 IPR032466 Metal-dependent hydrolase L21SP4_RS00220 ed9cc08441460c28b8d6fc1fb661ccf9 348 PANTHER PTHR11751:SF398 4 342 2.5E-86 T 22-04-2016 L21SP4_RS00220 ed9cc08441460c28b8d6fc1fb661ccf9 348 Gene3D G3DSA:3.40.640.10 122 220 9.5E-9 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 L21SP4_RS00220 ed9cc08441460c28b8d6fc1fb661ccf9 348 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 206 219 - T 22-04-2016 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 Reactome: REACT_13 L21SP4_RS00220 ed9cc08441460c28b8d6fc1fb661ccf9 348 Gene3D G3DSA:3.90.1150.10 14 121 3.7E-25 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 L21SP4_RS00220 ed9cc08441460c28b8d6fc1fb661ccf9 348 Pfam PF00155 Aminotransferase class I and II 26 342 1.1E-43 T 22-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 L21SP4_RS00220 ed9cc08441460c28b8d6fc1fb661ccf9 348 PANTHER PTHR11751 4 342 2.5E-86 T 22-04-2016 L21SP4_RS00220 ed9cc08441460c28b8d6fc1fb661ccf9 348 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 5 346 50.052 T 22-04-2016 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9|UniPathway: UPA00031 L21SP4_RS00220 ed9cc08441460c28b8d6fc1fb661ccf9 348 Gene3D G3DSA:3.90.1150.10 221 343 9.4E-45 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 L21SP4_RS00220 ed9cc08441460c28b8d6fc1fb661ccf9 348 SUPERFAMILY SSF53383 7 343 6.05E-80 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase L21SP4_RS00220 ed9cc08441460c28b8d6fc1fb661ccf9 348 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 7 343 2.3E-87 T 22-04-2016 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9|UniPathway: UPA00031 L21SP4_RS10770 5e2aebad193b53957495a1f52fa4c7c3 721 Pfam PF03633 Glycosyl hydrolase family 65, C-terminal domain 658 704 1.3E-4 T 22-04-2016 IPR005194 Glycoside hydrolase family 65, C-terminal L21SP4_RS10770 5e2aebad193b53957495a1f52fa4c7c3 721 Gene3D G3DSA:2.60.420.10 643 702 3.8E-9 T 22-04-2016 L21SP4_RS10770 5e2aebad193b53957495a1f52fa4c7c3 721 SUPERFAMILY SSF48208 304 687 8.75E-26 T 22-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP4_RS07655 8c8b970ccd6ddc35ff5af07bde77b6d4 352 Pfam PF00665 Integrase core domain 187 304 1.2E-10 T 22-04-2016 IPR001584 Integrase, catalytic core GO:0015074 L21SP4_RS07655 8c8b970ccd6ddc35ff5af07bde77b6d4 352 Pfam PF13936 Helix-turn-helix domain 9 52 2.4E-11 T 22-04-2016 IPR025246 Transposase IS30-like HTH domain L21SP4_RS07655 8c8b970ccd6ddc35ff5af07bde77b6d4 352 SUPERFAMILY SSF53098 188 346 2.47E-23 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS07655 8c8b970ccd6ddc35ff5af07bde77b6d4 352 Gene3D G3DSA:1.10.10.60 9 50 2.6E-4 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS07655 8c8b970ccd6ddc35ff5af07bde77b6d4 352 Gene3D G3DSA:3.30.420.10 188 346 1.1E-16 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS07655 8c8b970ccd6ddc35ff5af07bde77b6d4 352 PANTHER PTHR10948 5 344 5.2E-57 T 22-04-2016 L21SP4_RS07415 8c8b970ccd6ddc35ff5af07bde77b6d4 352 Pfam PF00665 Integrase core domain 187 304 1.2E-10 T 22-04-2016 IPR001584 Integrase, catalytic core GO:0015074 L21SP4_RS07415 8c8b970ccd6ddc35ff5af07bde77b6d4 352 Pfam PF13936 Helix-turn-helix domain 9 52 2.4E-11 T 22-04-2016 IPR025246 Transposase IS30-like HTH domain L21SP4_RS07415 8c8b970ccd6ddc35ff5af07bde77b6d4 352 SUPERFAMILY SSF53098 188 346 2.47E-23 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS07415 8c8b970ccd6ddc35ff5af07bde77b6d4 352 Gene3D G3DSA:1.10.10.60 9 50 2.6E-4 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS07415 8c8b970ccd6ddc35ff5af07bde77b6d4 352 Gene3D G3DSA:3.30.420.10 188 346 1.1E-16 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS07415 8c8b970ccd6ddc35ff5af07bde77b6d4 352 PANTHER PTHR10948 5 344 5.2E-57 T 22-04-2016 L21SP4_RS04470 8c8b970ccd6ddc35ff5af07bde77b6d4 352 Pfam PF00665 Integrase core domain 187 304 1.2E-10 T 22-04-2016 IPR001584 Integrase, catalytic core GO:0015074 L21SP4_RS04470 8c8b970ccd6ddc35ff5af07bde77b6d4 352 Pfam PF13936 Helix-turn-helix domain 9 52 2.4E-11 T 22-04-2016 IPR025246 Transposase IS30-like HTH domain L21SP4_RS04470 8c8b970ccd6ddc35ff5af07bde77b6d4 352 SUPERFAMILY SSF53098 188 346 2.47E-23 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS04470 8c8b970ccd6ddc35ff5af07bde77b6d4 352 Gene3D G3DSA:1.10.10.60 9 50 2.6E-4 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS04470 8c8b970ccd6ddc35ff5af07bde77b6d4 352 Gene3D G3DSA:3.30.420.10 188 346 1.1E-16 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS04470 8c8b970ccd6ddc35ff5af07bde77b6d4 352 PANTHER PTHR10948 5 344 5.2E-57 T 22-04-2016 L21SP4_RS10890 8c8b970ccd6ddc35ff5af07bde77b6d4 352 Pfam PF00665 Integrase core domain 187 304 1.2E-10 T 22-04-2016 IPR001584 Integrase, catalytic core GO:0015074 L21SP4_RS10890 8c8b970ccd6ddc35ff5af07bde77b6d4 352 Pfam PF13936 Helix-turn-helix domain 9 52 2.4E-11 T 22-04-2016 IPR025246 Transposase IS30-like HTH domain L21SP4_RS10890 8c8b970ccd6ddc35ff5af07bde77b6d4 352 SUPERFAMILY SSF53098 188 346 2.47E-23 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS10890 8c8b970ccd6ddc35ff5af07bde77b6d4 352 Gene3D G3DSA:1.10.10.60 9 50 2.6E-4 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS10890 8c8b970ccd6ddc35ff5af07bde77b6d4 352 Gene3D G3DSA:3.30.420.10 188 346 1.1E-16 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS10890 8c8b970ccd6ddc35ff5af07bde77b6d4 352 PANTHER PTHR10948 5 344 5.2E-57 T 22-04-2016 L21SP4_RS11515 8c8b970ccd6ddc35ff5af07bde77b6d4 352 Pfam PF00665 Integrase core domain 187 304 1.2E-10 T 22-04-2016 IPR001584 Integrase, catalytic core GO:0015074 L21SP4_RS11515 8c8b970ccd6ddc35ff5af07bde77b6d4 352 Pfam PF13936 Helix-turn-helix domain 9 52 2.4E-11 T 22-04-2016 IPR025246 Transposase IS30-like HTH domain L21SP4_RS11515 8c8b970ccd6ddc35ff5af07bde77b6d4 352 SUPERFAMILY SSF53098 188 346 2.47E-23 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS11515 8c8b970ccd6ddc35ff5af07bde77b6d4 352 Gene3D G3DSA:1.10.10.60 9 50 2.6E-4 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS11515 8c8b970ccd6ddc35ff5af07bde77b6d4 352 Gene3D G3DSA:3.30.420.10 188 346 1.1E-16 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS11515 8c8b970ccd6ddc35ff5af07bde77b6d4 352 PANTHER PTHR10948 5 344 5.2E-57 T 22-04-2016 L21SP4_RS06580 8c8b970ccd6ddc35ff5af07bde77b6d4 352 Pfam PF00665 Integrase core domain 187 304 1.2E-10 T 22-04-2016 IPR001584 Integrase, catalytic core GO:0015074 L21SP4_RS06580 8c8b970ccd6ddc35ff5af07bde77b6d4 352 Pfam PF13936 Helix-turn-helix domain 9 52 2.4E-11 T 22-04-2016 IPR025246 Transposase IS30-like HTH domain L21SP4_RS06580 8c8b970ccd6ddc35ff5af07bde77b6d4 352 SUPERFAMILY SSF53098 188 346 2.47E-23 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS06580 8c8b970ccd6ddc35ff5af07bde77b6d4 352 Gene3D G3DSA:1.10.10.60 9 50 2.6E-4 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS06580 8c8b970ccd6ddc35ff5af07bde77b6d4 352 Gene3D G3DSA:3.30.420.10 188 346 1.1E-16 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS06580 8c8b970ccd6ddc35ff5af07bde77b6d4 352 PANTHER PTHR10948 5 344 5.2E-57 T 22-04-2016 L21SP4_RS04755 8c8b970ccd6ddc35ff5af07bde77b6d4 352 Pfam PF00665 Integrase core domain 187 304 1.2E-10 T 22-04-2016 IPR001584 Integrase, catalytic core GO:0015074 L21SP4_RS04755 8c8b970ccd6ddc35ff5af07bde77b6d4 352 Pfam PF13936 Helix-turn-helix domain 9 52 2.4E-11 T 22-04-2016 IPR025246 Transposase IS30-like HTH domain L21SP4_RS04755 8c8b970ccd6ddc35ff5af07bde77b6d4 352 SUPERFAMILY SSF53098 188 346 2.47E-23 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS04755 8c8b970ccd6ddc35ff5af07bde77b6d4 352 Gene3D G3DSA:1.10.10.60 9 50 2.6E-4 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS04755 8c8b970ccd6ddc35ff5af07bde77b6d4 352 Gene3D G3DSA:3.30.420.10 188 346 1.1E-16 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS04755 8c8b970ccd6ddc35ff5af07bde77b6d4 352 PANTHER PTHR10948 5 344 5.2E-57 T 22-04-2016 L21SP4_RS01235 8c8b970ccd6ddc35ff5af07bde77b6d4 352 Pfam PF00665 Integrase core domain 187 304 1.2E-10 T 22-04-2016 IPR001584 Integrase, catalytic core GO:0015074 L21SP4_RS01235 8c8b970ccd6ddc35ff5af07bde77b6d4 352 Pfam PF13936 Helix-turn-helix domain 9 52 2.4E-11 T 22-04-2016 IPR025246 Transposase IS30-like HTH domain L21SP4_RS01235 8c8b970ccd6ddc35ff5af07bde77b6d4 352 SUPERFAMILY SSF53098 188 346 2.47E-23 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS01235 8c8b970ccd6ddc35ff5af07bde77b6d4 352 Gene3D G3DSA:1.10.10.60 9 50 2.6E-4 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS01235 8c8b970ccd6ddc35ff5af07bde77b6d4 352 Gene3D G3DSA:3.30.420.10 188 346 1.1E-16 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS01235 8c8b970ccd6ddc35ff5af07bde77b6d4 352 PANTHER PTHR10948 5 344 5.2E-57 T 22-04-2016 L21SP4_RS00660 8c8b970ccd6ddc35ff5af07bde77b6d4 352 Pfam PF00665 Integrase core domain 187 304 1.2E-10 T 22-04-2016 IPR001584 Integrase, catalytic core GO:0015074 L21SP4_RS00660 8c8b970ccd6ddc35ff5af07bde77b6d4 352 Pfam PF13936 Helix-turn-helix domain 9 52 2.4E-11 T 22-04-2016 IPR025246 Transposase IS30-like HTH domain L21SP4_RS00660 8c8b970ccd6ddc35ff5af07bde77b6d4 352 SUPERFAMILY SSF53098 188 346 2.47E-23 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS00660 8c8b970ccd6ddc35ff5af07bde77b6d4 352 Gene3D G3DSA:1.10.10.60 9 50 2.6E-4 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS00660 8c8b970ccd6ddc35ff5af07bde77b6d4 352 Gene3D G3DSA:3.30.420.10 188 346 1.1E-16 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS00660 8c8b970ccd6ddc35ff5af07bde77b6d4 352 PANTHER PTHR10948 5 344 5.2E-57 T 22-04-2016 L21SP4_RS10305 ed08f8d29cf51f79a3848e0142a5a56e 415 SUPERFAMILY SSF53901 221 412 5.15E-48 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 L21SP4_RS10305 ed08f8d29cf51f79a3848e0142a5a56e 415 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 277 369 1.0E-20 T 22-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal L21SP4_RS10305 ed08f8d29cf51f79a3848e0142a5a56e 415 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 5 250 1.2E-42 T 22-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal L21SP4_RS10305 ed08f8d29cf51f79a3848e0142a5a56e 415 Gene3D G3DSA:3.40.47.10 4 262 2.2E-53 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 L21SP4_RS10305 ed08f8d29cf51f79a3848e0142a5a56e 415 SMART SM00825 Beta-ketoacyl synthase 7 414 1.6E-8 T 22-04-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain L21SP4_RS10305 ed08f8d29cf51f79a3848e0142a5a56e 415 PANTHER PTHR11712 5 411 1.5E-86 T 22-04-2016 L21SP4_RS10305 ed08f8d29cf51f79a3848e0142a5a56e 415 SUPERFAMILY SSF53901 5 256 3.51E-56 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 L21SP4_RS10305 ed08f8d29cf51f79a3848e0142a5a56e 415 Gene3D G3DSA:3.40.47.10 275 412 3.5E-40 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 L21SP4_RS00150 abb79247b80bf3f198fcd43cca083ded 351 SUPERFAMILY SSF55347 155 319 1.08E-42 T 22-04-2016 L21SP4_RS00150 abb79247b80bf3f198fcd43cca083ded 351 Gene3D G3DSA:3.30.360.10 163 319 3.8E-45 T 22-04-2016 L21SP4_RS00150 abb79247b80bf3f198fcd43cca083ded 351 SUPERFAMILY SSF51735 1 168 3.53E-36 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS00150 abb79247b80bf3f198fcd43cca083ded 351 SMART SM00859 3 147 1.6E-35 T 22-04-2016 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 L21SP4_RS00150 abb79247b80bf3f198fcd43cca083ded 351 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 2 345 36.008 T 22-04-2016 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 L21SP4_RS00150 abb79247b80bf3f198fcd43cca083ded 351 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 170 322 3.0E-11 T 22-04-2016 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 L21SP4_RS00150 abb79247b80bf3f198fcd43cca083ded 351 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 4 146 3.9E-25 T 22-04-2016 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 L21SP4_RS00150 abb79247b80bf3f198fcd43cca083ded 351 PANTHER PTHR32338:SF8 1 351 4.1E-127 T 22-04-2016 L21SP4_RS00150 abb79247b80bf3f198fcd43cca083ded 351 Gene3D G3DSA:3.40.50.720 1 162 2.4E-46 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS00150 abb79247b80bf3f198fcd43cca083ded 351 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 2 351 2.5E-103 T 22-04-2016 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 L21SP4_RS00150 abb79247b80bf3f198fcd43cca083ded 351 PANTHER PTHR32338 1 351 4.1E-127 T 22-04-2016 L21SP4_RS07110 1a7976dc0d4fbe2951057fb94f23c429 432 Hamap MF_00303 Trigger factor [tig]. 2 432 18.498 T 22-04-2016 IPR005215 Trigger factor GO:0015031 L21SP4_RS07110 1a7976dc0d4fbe2951057fb94f23c429 432 SUPERFAMILY SSF102735 2 128 2.88E-31 T 22-04-2016 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 L21SP4_RS07110 1a7976dc0d4fbe2951057fb94f23c429 432 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 160 236 7.2E-7 T 22-04-2016 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 L21SP4_RS07110 1a7976dc0d4fbe2951057fb94f23c429 432 TIGRFAM TIGR00115 tig: trigger factor 12 425 5.4E-101 T 22-04-2016 IPR005215 Trigger factor GO:0015031 L21SP4_RS07110 1a7976dc0d4fbe2951057fb94f23c429 432 SUPERFAMILY SSF54534 94 251 3.34E-21 T 22-04-2016 L21SP4_RS07110 1a7976dc0d4fbe2951057fb94f23c429 432 Gene3D G3DSA:1.10.3120.10 223 401 6.2E-40 T 22-04-2016 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 L21SP4_RS07110 1a7976dc0d4fbe2951057fb94f23c429 432 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 272 426 1.7E-21 T 22-04-2016 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 L21SP4_RS07110 1a7976dc0d4fbe2951057fb94f23c429 432 SUPERFAMILY SSF109998 258 431 5.0E-30 T 22-04-2016 IPR027304 Trigger factor/SurA domain L21SP4_RS07110 1a7976dc0d4fbe2951057fb94f23c429 432 PIRSF PIRSF003095 2 432 5.0E-90 T 22-04-2016 IPR005215 Trigger factor GO:0015031 L21SP4_RS07110 1a7976dc0d4fbe2951057fb94f23c429 432 Gene3D G3DSA:3.30.70.1050 2 119 3.1E-30 T 22-04-2016 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 L21SP4_RS07110 1a7976dc0d4fbe2951057fb94f23c429 432 PANTHER PTHR30560 2 431 2.4E-81 T 22-04-2016 L21SP4_RS07110 1a7976dc0d4fbe2951057fb94f23c429 432 Gene3D G3DSA:3.10.50.40 154 222 4.2E-5 T 22-04-2016 L21SP4_RS07110 1a7976dc0d4fbe2951057fb94f23c429 432 Pfam PF05697 Bacterial trigger factor protein (TF) 2 145 3.2E-36 T 22-04-2016 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 L21SP4_RS09265 ba9eedd1f3790309aec59415107f33db 156 Gene3D G3DSA:3.30.700.10 1 61 3.4E-4 T 22-04-2016 L21SP4_RS09265 ba9eedd1f3790309aec59415107f33db 156 Pfam PF08334 Type II secretion system (T2SS), protein G 107 142 2.8E-4 T 22-04-2016 IPR013545 Type II secretion system protein G L21SP4_RS09265 ba9eedd1f3790309aec59415107f33db 156 SUPERFAMILY SSF54523 1 152 1.05E-13 T 22-04-2016 L21SP4_RS06280 5e4f06a8b7e3bdfa7b165d806ba164db 544 Gene3D G3DSA:3.40.50.720 315 467 4.9E-6 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS06280 5e4f06a8b7e3bdfa7b165d806ba164db 544 SUPERFAMILY SSF51735 316 466 3.19E-9 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS06280 5e4f06a8b7e3bdfa7b165d806ba164db 544 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 33 146 2.6E-6 T 22-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 L21SP4_RS06280 5e4f06a8b7e3bdfa7b165d806ba164db 544 Gene3D G3DSA:3.90.180.10 4 182 6.5E-22 T 22-04-2016 IPR011032 GroES-like L21SP4_RS06280 5e4f06a8b7e3bdfa7b165d806ba164db 544 SUPERFAMILY SSF50129 3 182 2.6E-19 T 22-04-2016 IPR011032 GroES-like L21SP4_RS00290 692ad8984a61b90aa39cb84d2e1dbe89 264 Gene3D G3DSA:3.40.50.300 28 189 5.8E-15 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS00290 692ad8984a61b90aa39cb84d2e1dbe89 264 SUPERFAMILY SSF52540 28 189 1.18E-22 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS00290 692ad8984a61b90aa39cb84d2e1dbe89 264 Pfam PF13469 Sulfotransferase family 102 189 4.7E-10 T 22-04-2016 L21SP4_RS00505 1896a92dad87d243f18398aba6a3aa0a 444 TIGRFAM TIGR00959 ffh: signal recognition particle protein 3 427 1.4E-170 T 22-04-2016 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 L21SP4_RS00505 1896a92dad87d243f18398aba6a3aa0a 444 Gene3D G3DSA:1.20.120.140 2 88 3.0E-31 T 22-04-2016 L21SP4_RS00505 1896a92dad87d243f18398aba6a3aa0a 444 Gene3D G3DSA:1.10.260.30 325 431 4.2E-38 T 22-04-2016 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 L21SP4_RS00505 1896a92dad87d243f18398aba6a3aa0a 444 Pfam PF00448 SRP54-type protein, GTPase domain 102 294 9.1E-68 T 22-04-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: REACT_15380 L21SP4_RS00505 1896a92dad87d243f18398aba6a3aa0a 444 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 1.2E-20 T 22-04-2016 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: REACT_15380 L21SP4_RS00505 1896a92dad87d243f18398aba6a3aa0a 444 PANTHER PTHR11564:SF7 1 433 7.1E-217 T 22-04-2016 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 L21SP4_RS00505 1896a92dad87d243f18398aba6a3aa0a 444 Pfam PF02978 Signal peptide binding domain 325 425 5.1E-33 T 22-04-2016 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 L21SP4_RS00505 1896a92dad87d243f18398aba6a3aa0a 444 SMART SM00963 1 86 2.7E-34 T 22-04-2016 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: REACT_15380 L21SP4_RS00505 1896a92dad87d243f18398aba6a3aa0a 444 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 436 32.214 T 22-04-2016 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 L21SP4_RS00505 1896a92dad87d243f18398aba6a3aa0a 444 Gene3D G3DSA:3.40.50.300 96 295 1.1E-64 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS00505 1896a92dad87d243f18398aba6a3aa0a 444 SMART SM00962 99 294 3.5E-92 T 22-04-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: REACT_15380 L21SP4_RS00505 1896a92dad87d243f18398aba6a3aa0a 444 SUPERFAMILY SSF47446 325 430 6.38E-35 T 22-04-2016 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 L21SP4_RS00505 1896a92dad87d243f18398aba6a3aa0a 444 SUPERFAMILY SSF52540 42 352 2.66E-45 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS00505 1896a92dad87d243f18398aba6a3aa0a 444 PANTHER PTHR11564 1 433 7.1E-217 T 22-04-2016 L21SP4_RS00505 1896a92dad87d243f18398aba6a3aa0a 444 SMART SM00382 98 299 2.9E-6 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS10955 ea0bbfdf65a6e8b68e8fb694c40c7045 137 Pfam PF02472 Biopolymer transport protein ExbD/TolR 13 134 2.1E-26 T 22-04-2016 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 L21SP4_RS10955 ea0bbfdf65a6e8b68e8fb694c40c7045 137 PANTHER PTHR30558 1 137 2.0E-28 T 22-04-2016 L21SP4_RS05150 221d196ab4581f40c6bf8584dbb872b2 240 Gene3D G3DSA:3.60.21.10 1 240 7.7E-74 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like L21SP4_RS05150 221d196ab4581f40c6bf8584dbb872b2 240 PIRSF PIRSF000883 1 240 3.1E-60 T 22-04-2016 IPR011152 Phosphoesterase MJ0912 L21SP4_RS05150 221d196ab4581f40c6bf8584dbb872b2 240 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 202 1.5E-26 T 22-04-2016 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type L21SP4_RS05150 221d196ab4581f40c6bf8584dbb872b2 240 PANTHER PTHR11124:SF2 177 240 1.2E-51 T 22-04-2016 L21SP4_RS05150 221d196ab4581f40c6bf8584dbb872b2 240 PANTHER PTHR11124:SF2 98 160 1.2E-51 T 22-04-2016 L21SP4_RS05150 221d196ab4581f40c6bf8584dbb872b2 240 PANTHER PTHR11124:SF2 1 72 1.2E-51 T 22-04-2016 L21SP4_RS05150 221d196ab4581f40c6bf8584dbb872b2 240 PANTHER PTHR11124 177 240 1.2E-51 T 22-04-2016 IPR000979 Phosphodiesterase MJ0936/Vps29 L21SP4_RS05150 221d196ab4581f40c6bf8584dbb872b2 240 PANTHER PTHR11124 98 160 1.2E-51 T 22-04-2016 IPR000979 Phosphodiesterase MJ0936/Vps29 L21SP4_RS05150 221d196ab4581f40c6bf8584dbb872b2 240 PANTHER PTHR11124 1 72 1.2E-51 T 22-04-2016 IPR000979 Phosphodiesterase MJ0936/Vps29 L21SP4_RS05150 221d196ab4581f40c6bf8584dbb872b2 240 SUPERFAMILY SSF56300 1 239 9.15E-60 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like L21SP4_RS04355 c8848c78514a175334bc3959e951d782 371 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 3 368 40.592 T 22-04-2016 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164|UniPathway: UPA00053 L21SP4_RS04355 c8848c78514a175334bc3959e951d782 371 Gene3D G3DSA:3.40.50.1970 4 172 1.4E-63 T 22-04-2016 L21SP4_RS04355 c8848c78514a175334bc3959e951d782 371 Gene3D G3DSA:1.20.1090.10 174 366 4.8E-64 T 22-04-2016 L21SP4_RS04355 c8848c78514a175334bc3959e951d782 371 PANTHER PTHR21090 1 371 7.3E-159 T 22-04-2016 L21SP4_RS04355 c8848c78514a175334bc3959e951d782 371 PIRSF PIRSF001455 9 364 1.3E-96 T 22-04-2016 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164|UniPathway: UPA00053 L21SP4_RS04355 c8848c78514a175334bc3959e951d782 371 Pfam PF01761 3-dehydroquinate synthase 68 335 3.1E-101 T 22-04-2016 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164|UniPathway: UPA00053 L21SP4_RS04355 c8848c78514a175334bc3959e951d782 371 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 14 353 1.4E-109 T 22-04-2016 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164|UniPathway: UPA00053 L21SP4_RS04355 c8848c78514a175334bc3959e951d782 371 SUPERFAMILY SSF56796 6 363 2.22E-111 T 22-04-2016 L21SP4_RS11310 3963eee194d41107f1ed8a8aadb72344 377 PANTHER PTHR18964 202 375 1.5E-106 T 22-04-2016 L21SP4_RS11310 3963eee194d41107f1ed8a8aadb72344 377 PANTHER PTHR18964 1 184 1.5E-106 T 22-04-2016 L21SP4_RS11310 3963eee194d41107f1ed8a8aadb72344 377 PANTHER PTHR18964:SF70 202 375 1.5E-106 T 22-04-2016 L21SP4_RS11310 3963eee194d41107f1ed8a8aadb72344 377 SUPERFAMILY SSF53756 1 375 2.59E-100 T 22-04-2016 L21SP4_RS11310 3963eee194d41107f1ed8a8aadb72344 377 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 26 373 1.9E-100 T 22-04-2016 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain L21SP4_RS11310 3963eee194d41107f1ed8a8aadb72344 377 Gene3D G3DSA:3.40.50.2000 2 213 4.4E-75 T 22-04-2016 L21SP4_RS11310 3963eee194d41107f1ed8a8aadb72344 377 Gene3D G3DSA:3.40.50.2000 214 374 1.4E-44 T 22-04-2016 L21SP4_RS11310 3963eee194d41107f1ed8a8aadb72344 377 PANTHER PTHR18964:SF70 1 184 1.5E-106 T 22-04-2016 L21SP4_RS11310 3963eee194d41107f1ed8a8aadb72344 377 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 1 375 2.6E-92 T 22-04-2016 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 KEGG: 00520+5.1.3.14|MetaCyc: PWY-7335 L21SP4_RS06970 c264302b45075874160a20000d8c495e 288 SUPERFAMILY SSF46689 186 235 2.33E-7 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS06970 c264302b45075874160a20000d8c495e 288 Gene3D G3DSA:2.60.120.280 59 131 1.0E-5 T 22-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 L21SP4_RS06970 c264302b45075874160a20000d8c495e 288 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 252 267 1.1E-5 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 L21SP4_RS06970 c264302b45075874160a20000d8c495e 288 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 267 283 1.1E-5 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 L21SP4_RS06970 c264302b45075874160a20000d8c495e 288 SUPERFAMILY SSF46689 237 286 1.83E-13 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS06970 c264302b45075874160a20000d8c495e 288 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 237 279 - T 22-04-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 L21SP4_RS06970 c264302b45075874160a20000d8c495e 288 Pfam PF12833 Helix-turn-helix domain 206 285 2.2E-21 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP4_RS06970 c264302b45075874160a20000d8c495e 288 SMART SM00342 200 283 2.4E-31 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP4_RS06970 c264302b45075874160a20000d8c495e 288 SUPERFAMILY SSF51215 59 160 1.16E-8 T 22-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 L21SP4_RS06970 c264302b45075874160a20000d8c495e 288 Gene3D G3DSA:1.10.10.60 181 236 3.0E-14 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS06970 c264302b45075874160a20000d8c495e 288 Gene3D G3DSA:1.10.10.60 237 286 6.5E-18 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS06970 c264302b45075874160a20000d8c495e 288 PANTHER PTHR11019 34 288 6.0E-30 T 22-04-2016 L21SP4_RS04440 36d23a534ae6b562f31b211ce4b3c77e 1090 SUPERFAMILY SSF51126 18 380 6.28E-12 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor L21SP4_RS04440 36d23a534ae6b562f31b211ce4b3c77e 1090 Gene3D G3DSA:2.160.20.10 1014 1055 4.5E-15 T 22-04-2016 IPR012334 Pectin lyase fold L21SP4_RS04440 36d23a534ae6b562f31b211ce4b3c77e 1090 Gene3D G3DSA:2.160.20.10 862 935 4.5E-15 T 22-04-2016 IPR012334 Pectin lyase fold L21SP4_RS04440 36d23a534ae6b562f31b211ce4b3c77e 1090 Gene3D G3DSA:2.160.20.10 733 803 4.5E-15 T 22-04-2016 IPR012334 Pectin lyase fold L21SP4_RS04440 36d23a534ae6b562f31b211ce4b3c77e 1090 Pfam PF12951 Passenger-associated-transport-repeat 249 276 7.5E-5 T 22-04-2016 IPR013425 Autotransporter-associated beta strand repeat L21SP4_RS04440 36d23a534ae6b562f31b211ce4b3c77e 1090 Pfam PF12951 Passenger-associated-transport-repeat 589 618 6.2E-9 T 22-04-2016 IPR013425 Autotransporter-associated beta strand repeat L21SP4_RS04440 36d23a534ae6b562f31b211ce4b3c77e 1090 Pfam PF12951 Passenger-associated-transport-repeat 125 143 0.0086 T 22-04-2016 IPR013425 Autotransporter-associated beta strand repeat L21SP4_RS04440 36d23a534ae6b562f31b211ce4b3c77e 1090 Pfam PF12708 Pectate lyase superfamily protein 733 820 3.7E-7 T 22-04-2016 IPR024535 Pectate lyase superfamily protein L21SP4_RS04440 36d23a534ae6b562f31b211ce4b3c77e 1090 SUPERFAMILY SSF51126 566 673 2.98E-8 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor L21SP4_RS04440 36d23a534ae6b562f31b211ce4b3c77e 1090 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 246 276 1.1E-5 T 22-04-2016 IPR013425 Autotransporter-associated beta strand repeat L21SP4_RS04440 36d23a534ae6b562f31b211ce4b3c77e 1090 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 588 619 6.4E-11 T 22-04-2016 IPR013425 Autotransporter-associated beta strand repeat L21SP4_RS04440 36d23a534ae6b562f31b211ce4b3c77e 1090 SUPERFAMILY SSF51126 728 957 4.97E-18 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor L21SP4_RS04440 36d23a534ae6b562f31b211ce4b3c77e 1090 SUPERFAMILY SSF51126 1031 1061 4.97E-18 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor L21SP4_RS04440 36d23a534ae6b562f31b211ce4b3c77e 1090 Gene3D G3DSA:2.160.20.20 246 337 6.9E-6 T 22-04-2016 IPR012332 P22 tailspike C-terminal domain-like L21SP4_RS04440 36d23a534ae6b562f31b211ce4b3c77e 1090 Gene3D G3DSA:2.160.20.20 576 654 2.0E-7 T 22-04-2016 IPR012332 P22 tailspike C-terminal domain-like L21SP4_RS10700 d4f543546815c3dd7f2bb205924723d0 304 Pfam PF00480 ROK family 1 293 2.7E-53 T 22-04-2016 IPR000600 ROK family L21SP4_RS10700 d4f543546815c3dd7f2bb205924723d0 304 PANTHER PTHR18964:SF123 1 295 5.8E-61 T 22-04-2016 L21SP4_RS10700 d4f543546815c3dd7f2bb205924723d0 304 SUPERFAMILY SSF53067 2 296 1.62E-46 T 22-04-2016 L21SP4_RS10700 d4f543546815c3dd7f2bb205924723d0 304 ProSitePatterns PS01125 ROK family signature. 117 144 - T 22-04-2016 IPR000600 ROK family L21SP4_RS10700 d4f543546815c3dd7f2bb205924723d0 304 Gene3D G3DSA:3.30.420.40 2 121 2.2E-36 T 22-04-2016 L21SP4_RS10700 d4f543546815c3dd7f2bb205924723d0 304 Gene3D G3DSA:3.30.420.40 122 279 2.2E-44 T 22-04-2016 L21SP4_RS10700 d4f543546815c3dd7f2bb205924723d0 304 PANTHER PTHR18964 1 295 5.8E-61 T 22-04-2016 L21SP4_RS01570 b58067b6038e0cc6f6cdbef82b5fd524 235 SUPERFAMILY SSF46689 129 178 1.52E-7 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS01570 b58067b6038e0cc6f6cdbef82b5fd524 235 Gene3D G3DSA:1.10.10.60 181 229 1.4E-15 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS01570 b58067b6038e0cc6f6cdbef82b5fd524 235 Pfam PF12833 Helix-turn-helix domain 150 229 1.8E-20 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP4_RS01570 b58067b6038e0cc6f6cdbef82b5fd524 235 SMART SM00342 144 227 1.7E-25 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP4_RS01570 b58067b6038e0cc6f6cdbef82b5fd524 235 SUPERFAMILY SSF51215 2 48 1.83E-6 T 22-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 L21SP4_RS01570 b58067b6038e0cc6f6cdbef82b5fd524 235 Gene3D G3DSA:2.60.120.280 2 110 1.7E-6 T 22-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 L21SP4_RS01570 b58067b6038e0cc6f6cdbef82b5fd524 235 Gene3D G3DSA:1.10.10.60 128 180 1.7E-12 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS01570 b58067b6038e0cc6f6cdbef82b5fd524 235 SUPERFAMILY SSF46689 180 230 2.15E-12 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS01570 b58067b6038e0cc6f6cdbef82b5fd524 235 PANTHER PTHR11019 2 235 1.7E-26 T 22-04-2016 L21SP4_RS01570 b58067b6038e0cc6f6cdbef82b5fd524 235 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 211 227 5.6E-6 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 L21SP4_RS01570 b58067b6038e0cc6f6cdbef82b5fd524 235 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 196 211 5.6E-6 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 L21SP4_RS08360 cfd5044982e31d7d57a4aaa6483ddf01 92 SUPERFAMILY SSF50249 10 85 7.71E-27 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold L21SP4_RS08360 cfd5044982e31d7d57a4aaa6483ddf01 92 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 10 81 3.0E-19 T 22-04-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS08360 cfd5044982e31d7d57a4aaa6483ddf01 92 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 8 86 22.926 T 22-04-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS08360 cfd5044982e31d7d57a4aaa6483ddf01 92 PRINTS PR00973 Ribosomal protein S17 family signature 71 78 3.4E-9 T 22-04-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS08360 cfd5044982e31d7d57a4aaa6483ddf01 92 PRINTS PR00973 Ribosomal protein S17 family signature 61 71 3.4E-9 T 22-04-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS08360 cfd5044982e31d7d57a4aaa6483ddf01 92 PRINTS PR00973 Ribosomal protein S17 family signature 29 52 3.4E-9 T 22-04-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS08360 cfd5044982e31d7d57a4aaa6483ddf01 92 Pfam PF00366 Ribosomal protein S17 15 81 1.9E-26 T 22-04-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS08360 cfd5044982e31d7d57a4aaa6483ddf01 92 Gene3D G3DSA:2.40.50.140 10 84 1.1E-27 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold L21SP4_RS08360 cfd5044982e31d7d57a4aaa6483ddf01 92 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 10 81 2.3E-31 T 22-04-2016 IPR019984 Ribosomal protein S17, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS08360 cfd5044982e31d7d57a4aaa6483ddf01 92 PANTHER PTHR10744 7 84 1.8E-28 T 22-04-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS08360 cfd5044982e31d7d57a4aaa6483ddf01 92 PANTHER PTHR10744:SF1 7 84 1.8E-28 T 22-04-2016 L21SP4_RS08360 cfd5044982e31d7d57a4aaa6483ddf01 92 ProSitePatterns PS00056 Ribosomal protein S17 signature. 61 73 - T 22-04-2016 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS02855 a373e3596f090b6e8c3d5bec8438881c 239 Hamap MF_00427 Na(+)-translocating NADH-quinone reductase subunit C [nqrC]. 2 239 27.371 T 22-04-2016 IPR010204 Na(+)-translocating NADH-quinone reductase subunit C GO:0006814|GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0055114 L21SP4_RS02855 a373e3596f090b6e8c3d5bec8438881c 239 PANTHER PTHR37838:SF1 5 239 8.3E-50 T 22-04-2016 L21SP4_RS02855 a373e3596f090b6e8c3d5bec8438881c 239 PANTHER PTHR37838 5 239 8.3E-50 T 22-04-2016 L21SP4_RS02855 a373e3596f090b6e8c3d5bec8438881c 239 Pfam PF04205 FMN-binding domain 126 225 1.3E-13 T 22-04-2016 IPR007329 FMN-binding GO:0010181|GO:0016020 L21SP4_RS02855 a373e3596f090b6e8c3d5bec8438881c 239 SMART SM00900 126 228 7.7E-24 T 22-04-2016 IPR007329 FMN-binding GO:0010181|GO:0016020 L21SP4_RS11490 be0e96b9b8ac9429fac2108f9a383fe3 217 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 10 184 1.6E-37 T 22-04-2016 IPR001303 Class II aldolase/adducin N-terminal L21SP4_RS11490 be0e96b9b8ac9429fac2108f9a383fe3 217 PANTHER PTHR22789:SF0 1 217 7.6E-53 T 22-04-2016 L21SP4_RS11490 be0e96b9b8ac9429fac2108f9a383fe3 217 Gene3D G3DSA:3.40.225.10 6 210 8.0E-56 T 22-04-2016 IPR001303 Class II aldolase/adducin N-terminal L21SP4_RS11490 be0e96b9b8ac9429fac2108f9a383fe3 217 SUPERFAMILY SSF53639 6 212 9.22E-51 T 22-04-2016 IPR001303 Class II aldolase/adducin N-terminal L21SP4_RS11490 be0e96b9b8ac9429fac2108f9a383fe3 217 SMART SM01007 9 185 1.9E-47 T 22-04-2016 IPR001303 Class II aldolase/adducin N-terminal L21SP4_RS11490 be0e96b9b8ac9429fac2108f9a383fe3 217 PANTHER PTHR22789 1 217 7.6E-53 T 22-04-2016 L21SP4_RS00995 af16c298ba83f544b7dd265bc38c0137 363 PANTHER PTHR33619:SF3 26 360 5.1E-27 T 22-04-2016 L21SP4_RS00995 af16c298ba83f544b7dd265bc38c0137 363 Gene3D G3DSA:3.10.560.10 149 242 6.7E-14 T 22-04-2016 L21SP4_RS00995 af16c298ba83f544b7dd265bc38c0137 363 Gene3D G3DSA:3.10.560.10 247 330 2.3E-14 T 22-04-2016 L21SP4_RS00995 af16c298ba83f544b7dd265bc38c0137 363 Pfam PF10531 SLBB domain 250 295 1.5E-8 T 22-04-2016 IPR019554 Soluble ligand binding domain L21SP4_RS00995 af16c298ba83f544b7dd265bc38c0137 363 Pfam PF10531 SLBB domain 174 214 9.1E-7 T 22-04-2016 IPR019554 Soluble ligand binding domain L21SP4_RS00995 af16c298ba83f544b7dd265bc38c0137 363 PANTHER PTHR33619 26 360 5.1E-27 T 22-04-2016 L21SP4_RS00995 af16c298ba83f544b7dd265bc38c0137 363 Gene3D G3DSA:3.30.1950.10 80 148 2.3E-12 T 22-04-2016 L21SP4_RS00995 af16c298ba83f544b7dd265bc38c0137 363 Pfam PF02563 Polysaccharide biosynthesis/export protein 72 150 4.7E-13 T 22-04-2016 IPR003715 Polysaccharide export protein GO:0015159|GO:0015774|GO:0016020 L21SP4_RS08950 116bf0a0ccb92a9d8f46113d9ec36456 539 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 6 539 4.2E-165 T 22-04-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 L21SP4_RS08950 116bf0a0ccb92a9d8f46113d9ec36456 539 PIRSF PIRSF000414 1 539 5.0E-181 T 22-04-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 L21SP4_RS08950 116bf0a0ccb92a9d8f46113d9ec36456 539 Pfam PF02142 MGS-like domain 16 131 2.5E-26 T 22-04-2016 IPR011607 Methylglyoxal synthase-like domain L21SP4_RS08950 116bf0a0ccb92a9d8f46113d9ec36456 539 Gene3D G3DSA:3.40.140.20 370 529 4.4E-45 T 22-04-2016 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 L21SP4_RS08950 116bf0a0ccb92a9d8f46113d9ec36456 539 SUPERFAMILY SSF53927 216 539 1.1E-101 T 22-04-2016 IPR016193 Cytidine deaminase-like GO:0003824 L21SP4_RS08950 116bf0a0ccb92a9d8f46113d9ec36456 539 SMART SM00851 16 131 2.2E-48 T 22-04-2016 IPR011607 Methylglyoxal synthase-like domain L21SP4_RS08950 116bf0a0ccb92a9d8f46113d9ec36456 539 Pfam PF01808 AICARFT/IMPCHase bienzyme 136 455 4.2E-94 T 22-04-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 L21SP4_RS08950 116bf0a0ccb92a9d8f46113d9ec36456 539 Gene3D G3DSA:3.40.50.1380 2 189 6.8E-76 T 22-04-2016 IPR011607 Methylglyoxal synthase-like domain L21SP4_RS08950 116bf0a0ccb92a9d8f46113d9ec36456 539 PANTHER PTHR11692 2 539 6.1E-253 T 22-04-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 L21SP4_RS08950 116bf0a0ccb92a9d8f46113d9ec36456 539 PANTHER PTHR11692:SF2 2 539 6.1E-253 T 22-04-2016 L21SP4_RS08950 116bf0a0ccb92a9d8f46113d9ec36456 539 SMART SM00798 136 458 1.8E-139 T 22-04-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 L21SP4_RS08950 116bf0a0ccb92a9d8f46113d9ec36456 539 Gene3D G3DSA:3.40.140.20 245 360 6.8E-38 T 22-04-2016 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 L21SP4_RS08950 116bf0a0ccb92a9d8f46113d9ec36456 539 SUPERFAMILY SSF52335 4 197 2.88E-62 T 22-04-2016 IPR011607 Methylglyoxal synthase-like domain L21SP4_RS08950 116bf0a0ccb92a9d8f46113d9ec36456 539 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 4 539 37.684 T 22-04-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 L21SP4_RS05855 a0641fc2b22ecc24d1e5275d32953b28 340 Pfam PF13524 Glycosyl transferases group 1 229 314 4.0E-12 T 22-04-2016 L21SP4_RS09035 bd2b0375f609745326d619fc1cef6db5 302 Gene3D G3DSA:3.20.20.70 32 297 7.8E-63 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP4_RS09035 bd2b0375f609745326d619fc1cef6db5 302 SMART SM00729 61 269 7.4E-13 T 22-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 L21SP4_RS09035 bd2b0375f609745326d619fc1cef6db5 302 Pfam PF04055 Radical SAM superfamily 67 227 2.6E-17 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 L21SP4_RS09035 bd2b0375f609745326d619fc1cef6db5 302 PANTHER PTHR10949 14 300 1.2E-131 T 22-04-2016 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|UniPathway: UPA00538 L21SP4_RS09035 bd2b0375f609745326d619fc1cef6db5 302 Hamap MF_00206 Lipoyl synthase [lipA]. 1 299 124.927 T 22-04-2016 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|UniPathway: UPA00538 L21SP4_RS09035 bd2b0375f609745326d619fc1cef6db5 302 TIGRFAM TIGR00510 lipA: lipoyl synthase 4 294 6.6E-106 T 22-04-2016 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|UniPathway: UPA00538 L21SP4_RS09035 bd2b0375f609745326d619fc1cef6db5 302 SUPERFAMILY SSF102114 30 287 2.49E-56 T 22-04-2016 L21SP4_RS09035 bd2b0375f609745326d619fc1cef6db5 302 PIRSF PIRSF005963 1 302 1.8E-121 T 22-04-2016 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|UniPathway: UPA00538 L21SP4_RS00810 c1b0bbca64356a0814126342684a9741 273 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 6 148 2.0E-25 T 22-04-2016 IPR002178 PTS EIIA type-2 domain KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- L21SP4_RS00810 c1b0bbca64356a0814126342684a9741 273 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 54 70 - T 22-04-2016 IPR002178 PTS EIIA type-2 domain KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- L21SP4_RS00810 c1b0bbca64356a0814126342684a9741 273 SUPERFAMILY SSF55804 1 149 3.79E-32 T 22-04-2016 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: REACT_15518 L21SP4_RS00810 c1b0bbca64356a0814126342684a9741 273 PANTHER PTHR30505:SF5 1 159 4.3E-30 T 22-04-2016 L21SP4_RS00810 c1b0bbca64356a0814126342684a9741 273 Gene3D G3DSA:3.40.930.10 1 150 1.9E-36 T 22-04-2016 IPR002178 PTS EIIA type-2 domain KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- L21SP4_RS00810 c1b0bbca64356a0814126342684a9741 273 PANTHER PTHR30505 1 159 4.3E-30 T 22-04-2016 L21SP4_RS01120 1cb3f45d13b32acd111c85d6d57986a3 105 TIGRFAM TIGR00061 L21: ribosomal protein bL21 4 103 1.3E-36 T 22-04-2016 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS01120 1cb3f45d13b32acd111c85d6d57986a3 105 PANTHER PTHR21349 4 104 1.0E-41 T 22-04-2016 L21SP4_RS01120 1cb3f45d13b32acd111c85d6d57986a3 105 SUPERFAMILY SSF141091 4 103 1.83E-37 T 22-04-2016 IPR028909 Ribosomal protein L21-like GO:0005840 L21SP4_RS01120 1cb3f45d13b32acd111c85d6d57986a3 105 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 3 105 26.383 T 22-04-2016 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS01120 1cb3f45d13b32acd111c85d6d57986a3 105 ProSitePatterns PS01169 Ribosomal protein L21 signature. 74 96 - T 22-04-2016 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS01120 1cb3f45d13b32acd111c85d6d57986a3 105 Pfam PF00829 Ribosomal prokaryotic L21 protein 4 103 1.3E-39 T 22-04-2016 IPR028909 Ribosomal protein L21-like GO:0005840 L21SP4_RS05545 9d23ec2267a30a1345e4a29e22ab7e4d 595 Pfam PF13646 HEAT repeats 273 356 1.8E-6 T 22-04-2016 L21SP4_RS05545 9d23ec2267a30a1345e4a29e22ab7e4d 595 Pfam PF13646 HEAT repeats 94 165 1.5E-8 T 22-04-2016 L21SP4_RS05545 9d23ec2267a30a1345e4a29e22ab7e4d 595 SUPERFAMILY SSF48371 55 190 3.02E-7 T 22-04-2016 IPR016024 Armadillo-type fold GO:0005488 L21SP4_RS05545 9d23ec2267a30a1345e4a29e22ab7e4d 595 SUPERFAMILY SSF48371 165 359 5.76E-11 T 22-04-2016 IPR016024 Armadillo-type fold GO:0005488 L21SP4_RS05545 9d23ec2267a30a1345e4a29e22ab7e4d 595 SMART SM00567 E-Z type HEAT repeats 284 313 1100.0 T 22-04-2016 IPR004155 PBS lyase HEAT-like repeat L21SP4_RS05545 9d23ec2267a30a1345e4a29e22ab7e4d 595 SMART SM00567 E-Z type HEAT repeats 315 344 370.0 T 22-04-2016 IPR004155 PBS lyase HEAT-like repeat L21SP4_RS05545 9d23ec2267a30a1345e4a29e22ab7e4d 595 SMART SM00567 E-Z type HEAT repeats 94 123 24.0 T 22-04-2016 IPR004155 PBS lyase HEAT-like repeat L21SP4_RS05545 9d23ec2267a30a1345e4a29e22ab7e4d 595 SMART SM00567 E-Z type HEAT repeats 125 154 56.0 T 22-04-2016 IPR004155 PBS lyase HEAT-like repeat L21SP4_RS05545 9d23ec2267a30a1345e4a29e22ab7e4d 595 Gene3D G3DSA:1.25.10.10 161 361 1.8E-8 T 22-04-2016 IPR011989 Armadillo-like helical L21SP4_RS05545 9d23ec2267a30a1345e4a29e22ab7e4d 595 Pfam PF06439 Domain of Unknown Function (DUF1080) 414 589 1.0E-36 T 22-04-2016 IPR010496 Domain of unknown function DUF1080 L21SP4_RS05770 a49e9f79a00fbeacf3fb8746abd5637d 438 PANTHER PTHR30153 1 436 2.5E-148 T 22-04-2016 L21SP4_RS05770 a49e9f79a00fbeacf3fb8746abd5637d 438 SUPERFAMILY SSF48024 1 102 2.62E-20 T 22-04-2016 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 L21SP4_RS05770 a49e9f79a00fbeacf3fb8746abd5637d 438 Pfam PF00772 DnaB-like helicase N terminal domain 1 94 4.3E-21 T 22-04-2016 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 L21SP4_RS05770 a49e9f79a00fbeacf3fb8746abd5637d 438 SMART SM00382 184 393 0.0032 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS05770 a49e9f79a00fbeacf3fb8746abd5637d 438 Pfam PF03796 DnaB-like helicase C terminal domain 167 426 2.6E-97 T 22-04-2016 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 L21SP4_RS05770 a49e9f79a00fbeacf3fb8746abd5637d 438 SUPERFAMILY SSF52540 165 419 1.47E-45 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS05770 a49e9f79a00fbeacf3fb8746abd5637d 438 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 1 428 5.0E-138 T 22-04-2016 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 L21SP4_RS05770 a49e9f79a00fbeacf3fb8746abd5637d 438 Gene3D G3DSA:1.10.860.10 1 95 4.9E-22 T 22-04-2016 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal L21SP4_RS05770 a49e9f79a00fbeacf3fb8746abd5637d 438 Gene3D G3DSA:3.40.50.300 152 427 7.1E-89 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS07015 d28b81b931d8d03c13eafb65837dcd1e 463 PANTHER PTHR22912 1 451 2.0E-140 T 22-04-2016 L21SP4_RS07015 d28b81b931d8d03c13eafb65837dcd1e 463 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 320 2.8E-65 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP4_RS07015 d28b81b931d8d03c13eafb65837dcd1e 463 Gene3D G3DSA:3.50.50.60 1 137 2.0E-42 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP4_RS07015 d28b81b931d8d03c13eafb65837dcd1e 463 Gene3D G3DSA:3.30.390.30 327 457 2.4E-45 T 22-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 L21SP4_RS07015 d28b81b931d8d03c13eafb65837dcd1e 463 SUPERFAMILY SSF51905 1 331 1.99E-56 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP4_RS07015 d28b81b931d8d03c13eafb65837dcd1e 463 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 256 272 4.5E-35 T 22-04-2016 L21SP4_RS07015 d28b81b931d8d03c13eafb65837dcd1e 463 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 134 152 4.5E-35 T 22-04-2016 L21SP4_RS07015 d28b81b931d8d03c13eafb65837dcd1e 463 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 4.5E-35 T 22-04-2016 L21SP4_RS07015 d28b81b931d8d03c13eafb65837dcd1e 463 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 285 307 4.5E-35 T 22-04-2016 L21SP4_RS07015 d28b81b931d8d03c13eafb65837dcd1e 463 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 172 190 4.5E-35 T 22-04-2016 L21SP4_RS07015 d28b81b931d8d03c13eafb65837dcd1e 463 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 37 47 - T 22-04-2016 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 L21SP4_RS07015 d28b81b931d8d03c13eafb65837dcd1e 463 PANTHER PTHR22912:SF146 1 451 2.0E-140 T 22-04-2016 L21SP4_RS07015 d28b81b931d8d03c13eafb65837dcd1e 463 PIRSF PIRSF000350 1 449 5.6E-91 T 22-04-2016 L21SP4_RS07015 d28b81b931d8d03c13eafb65837dcd1e 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 257 271 3.1E-65 T 22-04-2016 L21SP4_RS07015 d28b81b931d8d03c13eafb65837dcd1e 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 422 442 3.1E-65 T 22-04-2016 L21SP4_RS07015 d28b81b931d8d03c13eafb65837dcd1e 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 3.1E-65 T 22-04-2016 L21SP4_RS07015 d28b81b931d8d03c13eafb65837dcd1e 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 300 307 3.1E-65 T 22-04-2016 L21SP4_RS07015 d28b81b931d8d03c13eafb65837dcd1e 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 36 51 3.1E-65 T 22-04-2016 L21SP4_RS07015 d28b81b931d8d03c13eafb65837dcd1e 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 400 415 3.1E-65 T 22-04-2016 L21SP4_RS07015 d28b81b931d8d03c13eafb65837dcd1e 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 172 197 3.1E-65 T 22-04-2016 L21SP4_RS07015 d28b81b931d8d03c13eafb65837dcd1e 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 335 356 3.1E-65 T 22-04-2016 L21SP4_RS07015 d28b81b931d8d03c13eafb65837dcd1e 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 137 146 3.1E-65 T 22-04-2016 L21SP4_RS07015 d28b81b931d8d03c13eafb65837dcd1e 463 SUPERFAMILY SSF55424 337 458 3.61E-38 T 22-04-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 L21SP4_RS07015 d28b81b931d8d03c13eafb65837dcd1e 463 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 339 447 1.0E-35 T 22-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 L21SP4_RS07015 d28b81b931d8d03c13eafb65837dcd1e 463 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 3 457 7.5E-151 T 22-04-2016 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084 L21SP4_RS07015 d28b81b931d8d03c13eafb65837dcd1e 463 Gene3D G3DSA:3.50.50.60 138 326 4.2E-47 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP4_RS07145 447ddd1aad42656b8e6b9c1dc0f053b9 293 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 120 289 6.4E-57 T 22-04-2016 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: REACT_11193|UniPathway: UPA00253 L21SP4_RS07145 447ddd1aad42656b8e6b9c1dc0f053b9 293 Gene3D G3DSA:3.20.20.70 141 280 2.4E-55 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP4_RS07145 447ddd1aad42656b8e6b9c1dc0f053b9 293 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 31 117 6.5E-23 T 22-04-2016 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 L21SP4_RS07145 447ddd1aad42656b8e6b9c1dc0f053b9 293 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 19 290 9.6E-90 T 22-04-2016 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|UniPathway: UPA00253 L21SP4_RS07145 447ddd1aad42656b8e6b9c1dc0f053b9 293 SUPERFAMILY SSF51690 120 290 6.28E-57 T 22-04-2016 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: REACT_11193|UniPathway: UPA00253 L21SP4_RS07145 447ddd1aad42656b8e6b9c1dc0f053b9 293 SUPERFAMILY SSF54675 16 119 1.65E-27 T 22-04-2016 L21SP4_RS07145 447ddd1aad42656b8e6b9c1dc0f053b9 293 PANTHER PTHR32179 16 293 4.9E-103 T 22-04-2016 L21SP4_RS07145 447ddd1aad42656b8e6b9c1dc0f053b9 293 Gene3D G3DSA:3.90.1170.20 15 140 6.3E-45 T 22-04-2016 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 L21SP4_RS07145 447ddd1aad42656b8e6b9c1dc0f053b9 293 PIRSF PIRSF006250 11 293 4.7E-87 T 22-04-2016 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD L21SP4_RS11475 1062bb65be2279133735aeca6e2c5da2 162 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 113 135 1.1E-44 T 22-04-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|UniPathway: UPA00241 L21SP4_RS11475 1062bb65be2279133735aeca6e2c5da2 162 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 21 42 1.1E-44 T 22-04-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|UniPathway: UPA00241 L21SP4_RS11475 1062bb65be2279133735aeca6e2c5da2 162 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 50 74 1.1E-44 T 22-04-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|UniPathway: UPA00241 L21SP4_RS11475 1062bb65be2279133735aeca6e2c5da2 162 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 86 102 1.1E-44 T 22-04-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|UniPathway: UPA00241 L21SP4_RS11475 1062bb65be2279133735aeca6e2c5da2 162 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 3 21 1.1E-44 T 22-04-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|UniPathway: UPA00241 L21SP4_RS11475 1062bb65be2279133735aeca6e2c5da2 162 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 5 63 7.8E-14 T 22-04-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 L21SP4_RS11475 1062bb65be2279133735aeca6e2c5da2 162 PANTHER PTHR21342 1 159 6.5E-74 T 22-04-2016 L21SP4_RS11475 1062bb65be2279133735aeca6e2c5da2 162 SUPERFAMILY SSF52374 2 157 6.52E-43 T 22-04-2016 L21SP4_RS11475 1062bb65be2279133735aeca6e2c5da2 162 PANTHER PTHR21342:SF1 1 159 6.5E-74 T 22-04-2016 L21SP4_RS11475 1062bb65be2279133735aeca6e2c5da2 162 Gene3D G3DSA:3.40.50.620 2 158 4.2E-52 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP4_RS11475 1062bb65be2279133735aeca6e2c5da2 162 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 3 159 34.915 T 22-04-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|UniPathway: UPA00241 L21SP4_RS11475 1062bb65be2279133735aeca6e2c5da2 162 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 5 158 6.3E-57 T 22-04-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|UniPathway: UPA00241 L21SP4_RS11475 1062bb65be2279133735aeca6e2c5da2 162 Pfam PF01467 Cytidylyltransferase-like 6 134 1.1E-20 T 22-04-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 L21SP4_RS00640 711b032667626d23709fc01a7a6cdb3b 380 SUPERFAMILY SSF46548 294 378 9.29E-11 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 L21SP4_RS00640 711b032667626d23709fc01a7a6cdb3b 380 Gene3D G3DSA:3.20.20.100 43 297 6.2E-21 T 22-04-2016 IPR023210 NADP-dependent oxidoreductase domain L21SP4_RS00640 711b032667626d23709fc01a7a6cdb3b 380 SUPERFAMILY SSF51430 43 294 5.24E-26 T 22-04-2016 IPR023210 NADP-dependent oxidoreductase domain L21SP4_RS00640 711b032667626d23709fc01a7a6cdb3b 380 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 352 363 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site L21SP4_RS00640 711b032667626d23709fc01a7a6cdb3b 380 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 299 310 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site L21SP4_RS00640 711b032667626d23709fc01a7a6cdb3b 380 Pfam PF12800 4Fe-4S binding domain 352 364 0.0094 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain L21SP4_RS00640 711b032667626d23709fc01a7a6cdb3b 380 Pfam PF12800 4Fe-4S binding domain 297 311 0.083 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain L21SP4_RS00640 711b032667626d23709fc01a7a6cdb3b 380 Gene3D G3DSA:1.10.1060.10 298 378 1.4E-9 T 22-04-2016 L21SP4_RS00640 711b032667626d23709fc01a7a6cdb3b 380 Pfam PF00248 Aldo/keto reductase family 72 235 2.3E-9 T 22-04-2016 IPR023210 NADP-dependent oxidoreductase domain L21SP4_RS00640 711b032667626d23709fc01a7a6cdb3b 380 PANTHER PTHR11732:SF14 43 317 2.0E-19 T 22-04-2016 L21SP4_RS00640 711b032667626d23709fc01a7a6cdb3b 380 PANTHER PTHR11732 43 317 2.0E-19 T 22-04-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta L21SP4_RS02110 002a90eb841347eeb19e4e18be25d86b 592 SUPERFAMILY SSF53098 141 524 4.25E-13 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS02110 002a90eb841347eeb19e4e18be25d86b 592 Pfam PF01609 Transposase DDE domain 230 507 1.9E-17 T 22-04-2016 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 L21SP4_RS03150 002a90eb841347eeb19e4e18be25d86b 592 SUPERFAMILY SSF53098 141 524 4.25E-13 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS03150 002a90eb841347eeb19e4e18be25d86b 592 Pfam PF01609 Transposase DDE domain 230 507 1.9E-17 T 22-04-2016 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 L21SP4_RS09470 002a90eb841347eeb19e4e18be25d86b 592 SUPERFAMILY SSF53098 141 524 4.25E-13 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS09470 002a90eb841347eeb19e4e18be25d86b 592 Pfam PF01609 Transposase DDE domain 230 507 1.9E-17 T 22-04-2016 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 L21SP4_RS09490 002a90eb841347eeb19e4e18be25d86b 592 SUPERFAMILY SSF53098 141 524 4.25E-13 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS09490 002a90eb841347eeb19e4e18be25d86b 592 Pfam PF01609 Transposase DDE domain 230 507 1.9E-17 T 22-04-2016 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 L21SP4_RS06935 3b6c239cc85b3b6ba629d5555c6fd888 613 PANTHER PTHR11819 4 561 2.9E-194 T 22-04-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 L21SP4_RS06935 3b6c239cc85b3b6ba629d5555c6fd888 613 PANTHER PTHR11819:SF77 4 561 2.9E-194 T 22-04-2016 L21SP4_RS06935 3b6c239cc85b3b6ba629d5555c6fd888 613 Pfam PF00474 Sodium:solute symporter family 36 459 4.1E-29 T 22-04-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 L21SP4_RS09285 edc69a78aa7118d8ffbfc892722050ae 287 PANTHER PTHR21091 16 287 3.4E-53 T 22-04-2016 L21SP4_RS09285 edc69a78aa7118d8ffbfc892722050ae 287 PANTHER PTHR21091:SF97 16 287 3.4E-53 T 22-04-2016 L21SP4_RS09285 edc69a78aa7118d8ffbfc892722050ae 287 Pfam PF02574 Homocysteine S-methyltransferase 16 287 3.2E-57 T 22-04-2016 IPR003726 Homocysteine-binding domain L21SP4_RS09285 edc69a78aa7118d8ffbfc892722050ae 287 Gene3D G3DSA:3.20.20.330 4 287 3.6E-81 T 22-04-2016 IPR003726 Homocysteine-binding domain L21SP4_RS09285 edc69a78aa7118d8ffbfc892722050ae 287 SUPERFAMILY SSF82282 11 287 1.44E-78 T 22-04-2016 IPR003726 Homocysteine-binding domain L21SP4_RS09285 edc69a78aa7118d8ffbfc892722050ae 287 PIRSF PIRSF037505 2 287 2.2E-13 T 22-04-2016 IPR017226 Betaine-homocysteine S-methyltransferase, BHMT GO:0005737|GO:0008270|GO:0009086|GO:0047150 UniPathway: UPA00051 L21SP4_RS07125 591640fc2076f7814a4874e5dda2544a 269 SUPERFAMILY SSF57716 219 268 6.27E-13 T 22-04-2016 L21SP4_RS07125 591640fc2076f7814a4874e5dda2544a 269 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 268 2.7E-73 T 22-04-2016 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 L21SP4_RS07125 591640fc2076f7814a4874e5dda2544a 269 Pfam PF06827 Zinc finger found in FPG and IleRS 241 269 2.9E-6 T 22-04-2016 IPR010663 Zinc finger, FPG/IleRS-type L21SP4_RS07125 591640fc2076f7814a4874e5dda2544a 269 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 118 2.7E-31 T 22-04-2016 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 L21SP4_RS07125 591640fc2076f7814a4874e5dda2544a 269 SUPERFAMILY SSF46946 127 213 4.84E-24 T 22-04-2016 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 L21SP4_RS07125 591640fc2076f7814a4874e5dda2544a 269 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 128 212 1.9E-22 T 22-04-2016 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 L21SP4_RS07125 591640fc2076f7814a4874e5dda2544a 269 SUPERFAMILY SSF81624 2 131 2.09E-29 T 22-04-2016 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 L21SP4_RS07125 591640fc2076f7814a4874e5dda2544a 269 SMART SM00898 2 119 2.7E-35 T 22-04-2016 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 L21SP4_RS07125 591640fc2076f7814a4874e5dda2544a 269 SMART SM01232 127 217 4.0E-33 T 22-04-2016 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 L21SP4_RS07125 591640fc2076f7814a4874e5dda2544a 269 Gene3D G3DSA:3.20.190.10 2 124 1.7E-35 T 22-04-2016 L21SP4_RS07125 591640fc2076f7814a4874e5dda2544a 269 PANTHER PTHR22993:SF15 1 268 2.5E-87 T 22-04-2016 L21SP4_RS07125 591640fc2076f7814a4874e5dda2544a 269 Gene3D G3DSA:1.10.8.50 128 269 2.2E-41 T 22-04-2016 L21SP4_RS07125 591640fc2076f7814a4874e5dda2544a 269 ProSitePatterns PS01242 Zinc finger FPG-type signature. 244 268 - T 22-04-2016 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 L21SP4_RS07125 591640fc2076f7814a4874e5dda2544a 269 PANTHER PTHR22993 1 268 2.5E-87 T 22-04-2016 L21SP4_RS07605 72be14aa38f20bdc93735d6e3a52dd79 135 PANTHER PTHR30558:SF3 6 135 1.3E-25 T 22-04-2016 L21SP4_RS07605 72be14aa38f20bdc93735d6e3a52dd79 135 PANTHER PTHR30558 6 135 1.3E-25 T 22-04-2016 L21SP4_RS07605 72be14aa38f20bdc93735d6e3a52dd79 135 Pfam PF02472 Biopolymer transport protein ExbD/TolR 13 132 3.5E-27 T 22-04-2016 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 L21SP4_RS06860 8f5bafb6ad0f5a7263fc1a9e6b1a6259 632 SUPERFAMILY SSF53795 235 608 5.31E-30 T 22-04-2016 L21SP4_RS06860 8f5bafb6ad0f5a7263fc1a9e6b1a6259 632 Pfam PF16260 Domain of unknown function (DUF4914) 12 623 0.0 T 22-04-2016 IPR032583 Protein of unknown function DUF4914 L21SP4_RS00245 1b2bfe0298a8445b289cdf0758f73ce4 191 Pfam PF03358 NADPH-dependent FMN reductase 1 160 1.1E-26 T 22-04-2016 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 L21SP4_RS00245 1b2bfe0298a8445b289cdf0758f73ce4 191 PANTHER PTHR10204 1 116 4.3E-30 T 22-04-2016 L21SP4_RS00245 1b2bfe0298a8445b289cdf0758f73ce4 191 Gene3D G3DSA:3.40.50.360 1 185 1.5E-33 T 22-04-2016 IPR029039 Flavoprotein-like domain L21SP4_RS00245 1b2bfe0298a8445b289cdf0758f73ce4 191 SUPERFAMILY SSF52218 1 190 1.3E-35 T 22-04-2016 IPR029039 Flavoprotein-like domain L21SP4_RS00245 1b2bfe0298a8445b289cdf0758f73ce4 191 PANTHER PTHR10204:SF38 1 116 4.3E-30 T 22-04-2016 L21SP4_RS07650 6128882867110c9272369dd058dbe6c1 674 Gene3D G3DSA:2.170.130.10 17 144 1.0E-35 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 L21SP4_RS07650 6128882867110c9272369dd058dbe6c1 674 Gene3D G3DSA:2.40.170.20 145 674 1.4E-85 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 L21SP4_RS07650 6128882867110c9272369dd058dbe6c1 674 SUPERFAMILY SSF56935 15 674 6.96E-114 T 22-04-2016 L21SP4_RS07650 6128882867110c9272369dd058dbe6c1 674 PANTHER PTHR32552 19 674 3.6E-67 T 22-04-2016 L21SP4_RS07650 6128882867110c9272369dd058dbe6c1 674 Pfam PF07715 TonB-dependent Receptor Plug Domain 39 141 2.3E-22 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 L21SP4_RS07650 6128882867110c9272369dd058dbe6c1 674 Pfam PF00593 TonB dependent receptor 431 671 3.9E-33 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 L21SP4_RS00375 e686c59d85bd3ed500595229fb3fb87e 312 SUPERFAMILY SSF53649 25 300 7.2E-78 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS00375 e686c59d85bd3ed500595229fb3fb87e 312 ProSitePatterns PS00523 Sulfatases signature 1. 72 84 - T 22-04-2016 IPR024607 Sulfatase, conserved site L21SP4_RS00375 e686c59d85bd3ed500595229fb3fb87e 312 Pfam PF00884 Sulfatase 144 298 3.3E-27 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS00375 e686c59d85bd3ed500595229fb3fb87e 312 Pfam PF00884 Sulfatase 27 131 3.5E-26 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS00375 e686c59d85bd3ed500595229fb3fb87e 312 PANTHER PTHR10342 2 298 1.0E-77 T 22-04-2016 L21SP4_RS00375 e686c59d85bd3ed500595229fb3fb87e 312 Gene3D G3DSA:3.40.720.10 24 131 4.0E-36 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS00375 e686c59d85bd3ed500595229fb3fb87e 312 Gene3D G3DSA:3.40.720.10 156 299 8.9E-34 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS01445 404195aa7f1580bc8b27e7dbb7240892 222 PANTHER PTHR10010 1 221 2.3E-60 T 22-04-2016 L21SP4_RS01445 404195aa7f1580bc8b27e7dbb7240892 222 Gene3D G3DSA:1.20.58.220 118 217 4.4E-28 T 22-04-2016 L21SP4_RS01445 404195aa7f1580bc8b27e7dbb7240892 222 PANTHER PTHR10010:SF14 1 221 2.3E-60 T 22-04-2016 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 L21SP4_RS01445 404195aa7f1580bc8b27e7dbb7240892 222 Gene3D G3DSA:1.20.58.220 3 103 5.8E-29 T 22-04-2016 L21SP4_RS01445 404195aa7f1580bc8b27e7dbb7240892 222 Pfam PF01895 PhoU domain 20 103 1.4E-20 T 22-04-2016 IPR026022 PhoU domain L21SP4_RS01445 404195aa7f1580bc8b27e7dbb7240892 222 Pfam PF01895 PhoU domain 119 203 1.5E-18 T 22-04-2016 IPR026022 PhoU domain L21SP4_RS01445 404195aa7f1580bc8b27e7dbb7240892 222 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 4 212 6.1E-64 T 22-04-2016 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 L21SP4_RS01445 404195aa7f1580bc8b27e7dbb7240892 222 PIRSF PIRSF003107 1 217 3.0E-65 T 22-04-2016 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 L21SP4_RS01445 404195aa7f1580bc8b27e7dbb7240892 222 SUPERFAMILY SSF109755 4 216 5.13E-62 T 22-04-2016 L21SP4_RS04365 1ddab18df175eb444a17a11053ccd825 842 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 294 308 - T 22-04-2016 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 L21SP4_RS04365 1ddab18df175eb444a17a11053ccd825 842 Pfam PF01131 DNA topoisomerase 130 566 1.8E-118 T 22-04-2016 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 L21SP4_RS04365 1ddab18df175eb444a17a11053ccd825 842 Pfam PF01751 Toprim domain 5 115 2.3E-22 T 22-04-2016 IPR006171 Toprim domain L21SP4_RS04365 1ddab18df175eb444a17a11053ccd825 842 SMART SM00493 3 103 1.5E-23 T 22-04-2016 IPR006171 Toprim domain L21SP4_RS04365 1ddab18df175eb444a17a11053ccd825 842 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 484 498 1.4E-35 T 22-04-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 L21SP4_RS04365 1ddab18df175eb444a17a11053ccd825 842 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 375 391 1.4E-35 T 22-04-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 L21SP4_RS04365 1ddab18df175eb444a17a11053ccd825 842 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 299 308 1.4E-35 T 22-04-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 L21SP4_RS04365 1ddab18df175eb444a17a11053ccd825 842 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 164 182 1.4E-35 T 22-04-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 L21SP4_RS04365 1ddab18df175eb444a17a11053ccd825 842 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 77 90 1.4E-35 T 22-04-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 L21SP4_RS04365 1ddab18df175eb444a17a11053ccd825 842 SMART SM00437 257 521 9.7E-108 T 22-04-2016 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 L21SP4_RS04365 1ddab18df175eb444a17a11053ccd825 842 SMART SM00436 106 194 3.4E-39 T 22-04-2016 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 L21SP4_RS04365 1ddab18df175eb444a17a11053ccd825 842 Hamap MF_00952 DNA topoisomerase 1 [topA]. 3 611 44.717 T 22-04-2016 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 L21SP4_RS04365 1ddab18df175eb444a17a11053ccd825 842 PANTHER PTHR11390 1 580 3.7E-237 T 22-04-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 L21SP4_RS04365 1ddab18df175eb444a17a11053ccd825 842 Gene3D G3DSA:3.40.50.140 1 135 4.2E-38 T 22-04-2016 IPR006171 Toprim domain L21SP4_RS04365 1ddab18df175eb444a17a11053ccd825 842 Gene3D G3DSA:2.70.20.10 188 319 1.1E-17 T 22-04-2016 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 L21SP4_RS04365 1ddab18df175eb444a17a11053ccd825 842 Gene3D G3DSA:2.70.20.10 322 460 1.1E-25 T 22-04-2016 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 L21SP4_RS04365 1ddab18df175eb444a17a11053ccd825 842 Gene3D G3DSA:1.10.460.10 136 187 6.1E-52 T 22-04-2016 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 L21SP4_RS04365 1ddab18df175eb444a17a11053ccd825 842 Gene3D G3DSA:1.10.460.10 461 580 6.1E-52 T 22-04-2016 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 L21SP4_RS04365 1ddab18df175eb444a17a11053ccd825 842 PANTHER PTHR11390:SF27 1 580 3.7E-237 T 22-04-2016 L21SP4_RS04365 1ddab18df175eb444a17a11053ccd825 842 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 5 582 8.5E-191 T 22-04-2016 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 L21SP4_RS04365 1ddab18df175eb444a17a11053ccd825 842 SUPERFAMILY SSF56712 3 580 5.23E-170 T 22-04-2016 IPR023405 DNA topoisomerase, type IA, core domain L21SP4_RS10875 302a09e939ea7a6fb7d7ff8e80b7fd2d 851 PANTHER PTHR11946:SF7 256 281 0.0 T 22-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 L21SP4_RS10875 302a09e939ea7a6fb7d7ff8e80b7fd2d 851 PANTHER PTHR11946:SF7 1 215 0.0 T 22-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 L21SP4_RS10875 302a09e939ea7a6fb7d7ff8e80b7fd2d 851 PANTHER PTHR11946:SF7 305 476 0.0 T 22-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 L21SP4_RS10875 302a09e939ea7a6fb7d7ff8e80b7fd2d 851 PANTHER PTHR11946:SF7 492 848 0.0 T 22-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 L21SP4_RS10875 302a09e939ea7a6fb7d7ff8e80b7fd2d 851 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 438 639 7.4E-21 T 22-04-2016 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 L21SP4_RS10875 302a09e939ea7a6fb7d7ff8e80b7fd2d 851 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 13 850 22.835 T 22-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 L21SP4_RS10875 302a09e939ea7a6fb7d7ff8e80b7fd2d 851 SUPERFAMILY SSF47323 648 849 9.72E-37 T 22-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 L21SP4_RS10875 302a09e939ea7a6fb7d7ff8e80b7fd2d 851 Gene3D G3DSA:3.40.50.620 445 632 9.3E-156 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP4_RS10875 302a09e939ea7a6fb7d7ff8e80b7fd2d 851 Gene3D G3DSA:3.40.50.620 13 231 9.3E-156 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP4_RS10875 302a09e939ea7a6fb7d7ff8e80b7fd2d 851 PANTHER PTHR11946 256 281 0.0 T 22-04-2016 L21SP4_RS10875 302a09e939ea7a6fb7d7ff8e80b7fd2d 851 PANTHER PTHR11946 1 215 0.0 T 22-04-2016 L21SP4_RS10875 302a09e939ea7a6fb7d7ff8e80b7fd2d 851 PANTHER PTHR11946 305 476 0.0 T 22-04-2016 L21SP4_RS10875 302a09e939ea7a6fb7d7ff8e80b7fd2d 851 PANTHER PTHR11946 492 848 0.0 T 22-04-2016 L21SP4_RS10875 302a09e939ea7a6fb7d7ff8e80b7fd2d 851 PRINTS PR00985 Leucyl-tRNA synthetase signature 580 590 1.9E-52 T 22-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 L21SP4_RS10875 302a09e939ea7a6fb7d7ff8e80b7fd2d 851 PRINTS PR00985 Leucyl-tRNA synthetase signature 162 178 1.9E-52 T 22-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 L21SP4_RS10875 302a09e939ea7a6fb7d7ff8e80b7fd2d 851 PRINTS PR00985 Leucyl-tRNA synthetase signature 194 207 1.9E-52 T 22-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 L21SP4_RS10875 302a09e939ea7a6fb7d7ff8e80b7fd2d 851 PRINTS PR00985 Leucyl-tRNA synthetase signature 508 526 1.9E-52 T 22-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 L21SP4_RS10875 302a09e939ea7a6fb7d7ff8e80b7fd2d 851 PRINTS PR00985 Leucyl-tRNA synthetase signature 136 153 1.9E-52 T 22-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 L21SP4_RS10875 302a09e939ea7a6fb7d7ff8e80b7fd2d 851 PRINTS PR00985 Leucyl-tRNA synthetase signature 224 243 1.9E-52 T 22-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 L21SP4_RS10875 302a09e939ea7a6fb7d7ff8e80b7fd2d 851 PRINTS PR00985 Leucyl-tRNA synthetase signature 547 569 1.9E-52 T 22-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 L21SP4_RS10875 302a09e939ea7a6fb7d7ff8e80b7fd2d 851 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 51 62 - T 22-04-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 L21SP4_RS10875 302a09e939ea7a6fb7d7ff8e80b7fd2d 851 Gene3D G3DSA:1.10.730.10 633 786 2.0E-44 T 22-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 L21SP4_RS10875 302a09e939ea7a6fb7d7ff8e80b7fd2d 851 SUPERFAMILY SSF50677 235 435 1.57E-43 T 22-04-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Reactome: REACT_71 L21SP4_RS10875 302a09e939ea7a6fb7d7ff8e80b7fd2d 851 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 15 849 0.0 T 22-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 L21SP4_RS10875 302a09e939ea7a6fb7d7ff8e80b7fd2d 851 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 230 423 8.8E-61 T 22-04-2016 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 L21SP4_RS10875 302a09e939ea7a6fb7d7ff8e80b7fd2d 851 SUPERFAMILY SSF52374 13 235 2.16E-149 T 22-04-2016 L21SP4_RS10875 302a09e939ea7a6fb7d7ff8e80b7fd2d 851 SUPERFAMILY SSF52374 436 652 2.16E-149 T 22-04-2016 L21SP4_RS10875 302a09e939ea7a6fb7d7ff8e80b7fd2d 851 Gene3D G3DSA:3.90.740.10 232 444 2.1E-50 T 22-04-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Reactome: REACT_71 L21SP4_RS10875 302a09e939ea7a6fb7d7ff8e80b7fd2d 851 Pfam PF08264 Anticodon-binding domain of tRNA 687 813 5.1E-23 T 22-04-2016 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 Reactome: REACT_71 L21SP4_RS10875 302a09e939ea7a6fb7d7ff8e80b7fd2d 851 Pfam PF09334 tRNA synthetases class I (M) 50 191 6.6E-22 T 22-04-2016 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 L21SP4_RS08730 62dd30d6f4f98f612b881fbcda1ad601 410 Hamap MF_01283 Riboflavin biosynthesis protein RibBA [ribBA]. 12 408 50.871 T 22-04-2016 IPR016299 Riboflavin biosynthesis protein RibBA GO:0009231 KEGG: 00740+3.5.4.25+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7539|UniPathway: UPA00275|UniPathway: UPA00275 L21SP4_RS08730 62dd30d6f4f98f612b881fbcda1ad601 410 PIRSF PIRSF001259 13 410 1.8E-167 T 22-04-2016 L21SP4_RS08730 62dd30d6f4f98f612b881fbcda1ad601 410 SUPERFAMILY SSF55821 15 218 3.2E-77 T 22-04-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain L21SP4_RS08730 62dd30d6f4f98f612b881fbcda1ad601 410 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 17 211 1.5E-70 T 22-04-2016 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 L21SP4_RS08730 62dd30d6f4f98f612b881fbcda1ad601 410 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 18 209 2.3E-79 T 22-04-2016 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 L21SP4_RS08730 62dd30d6f4f98f612b881fbcda1ad601 410 PANTHER PTHR21327 14 410 1.5E-216 T 22-04-2016 L21SP4_RS08730 62dd30d6f4f98f612b881fbcda1ad601 410 SUPERFAMILY SSF142695 217 388 1.22E-66 T 22-04-2016 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|UniPathway: UPA00275 L21SP4_RS08730 62dd30d6f4f98f612b881fbcda1ad601 410 Pfam PF00925 GTP cyclohydrolase II 222 386 2.7E-70 T 22-04-2016 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|UniPathway: UPA00275 L21SP4_RS08730 62dd30d6f4f98f612b881fbcda1ad601 410 PANTHER PTHR21327:SF6 14 410 1.5E-216 T 22-04-2016 L21SP4_RS08730 62dd30d6f4f98f612b881fbcda1ad601 410 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 216 410 38.532 T 22-04-2016 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|UniPathway: UPA00275 L21SP4_RS08730 62dd30d6f4f98f612b881fbcda1ad601 410 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 221 410 1.9E-70 T 22-04-2016 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|UniPathway: UPA00275 L21SP4_RS08730 62dd30d6f4f98f612b881fbcda1ad601 410 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 11 215 36.048 T 22-04-2016 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 L21SP4_RS08730 62dd30d6f4f98f612b881fbcda1ad601 410 Gene3D G3DSA:3.90.870.10 14 222 1.3E-86 T 22-04-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain L21SP4_RS10450 66811209d36bb9bbbb3c30e5894da6cb 1275 Gene3D G3DSA:3.20.20.80 746 1027 6.7E-60 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP4_RS10450 66811209d36bb9bbbb3c30e5894da6cb 1275 Gene3D G3DSA:2.60.40.320 618 741 9.8E-23 T 22-04-2016 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 L21SP4_RS10450 66811209d36bb9bbbb3c30e5894da6cb 1275 SUPERFAMILY SSF51445 748 1028 7.04E-56 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily L21SP4_RS10450 66811209d36bb9bbbb3c30e5894da6cb 1275 ProSitePatterns PS00523 Sulfatases signature 1. 45 57 - T 22-04-2016 IPR024607 Sulfatase, conserved site L21SP4_RS10450 66811209d36bb9bbbb3c30e5894da6cb 1275 Gene3D G3DSA:2.60.40.1560 1029 1116 1.6E-25 T 22-04-2016 L21SP4_RS10450 66811209d36bb9bbbb3c30e5894da6cb 1275 PANTHER PTHR10066 957 1138 6.4E-156 T 22-04-2016 L21SP4_RS10450 66811209d36bb9bbbb3c30e5894da6cb 1275 PANTHER PTHR10066 456 935 6.4E-156 T 22-04-2016 L21SP4_RS10450 66811209d36bb9bbbb3c30e5894da6cb 1275 ProSitePatterns PS00149 Sulfatases signature 2. 104 114 - T 22-04-2016 IPR024607 Sulfatase, conserved site L21SP4_RS10450 66811209d36bb9bbbb3c30e5894da6cb 1275 Pfam PF16347 Domain of unknown function (DUF4976) 327 418 6.7E-9 T 22-04-2016 IPR032506 Domain of unknown function DUF4976 L21SP4_RS10450 66811209d36bb9bbbb3c30e5894da6cb 1275 PANTHER PTHR10066:SF71 957 1138 6.4E-156 T 22-04-2016 L21SP4_RS10450 66811209d36bb9bbbb3c30e5894da6cb 1275 PANTHER PTHR10066:SF71 456 935 6.4E-156 T 22-04-2016 L21SP4_RS10450 66811209d36bb9bbbb3c30e5894da6cb 1275 Pfam PF00884 Sulfatase 2 320 2.6E-70 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS10450 66811209d36bb9bbbb3c30e5894da6cb 1275 SUPERFAMILY SSF49785 458 627 1.58E-36 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS10450 66811209d36bb9bbbb3c30e5894da6cb 1275 Gene3D G3DSA:3.40.720.10 2 360 6.7E-102 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS10450 66811209d36bb9bbbb3c30e5894da6cb 1275 Gene3D G3DSA:2.60.120.260 457 617 1.8E-36 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS10450 66811209d36bb9bbbb3c30e5894da6cb 1275 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 752 829 1.1E-8 T 22-04-2016 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP4_RS10450 66811209d36bb9bbbb3c30e5894da6cb 1275 Pfam PF00703 Glycosyl hydrolases family 2 629 741 2.9E-13 T 22-04-2016 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 L21SP4_RS10450 66811209d36bb9bbbb3c30e5894da6cb 1275 Pfam PF16355 Domain of unknown function (DUF4982) 1042 1100 6.6E-19 T 22-04-2016 IPR032311 Domain of unknown function DUF4982 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP4_RS10450 66811209d36bb9bbbb3c30e5894da6cb 1275 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 499 625 4.6E-16 T 22-04-2016 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP4_RS10450 66811209d36bb9bbbb3c30e5894da6cb 1275 SUPERFAMILY SSF53649 2 420 1.05E-122 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS10450 66811209d36bb9bbbb3c30e5894da6cb 1275 SUPERFAMILY SSF49303 635 741 1.35E-12 T 22-04-2016 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 L21SP4_RS10450 66811209d36bb9bbbb3c30e5894da6cb 1275 Gene3D G3DSA:3.30.1120.10 361 427 2.1E-20 T 22-04-2016 L21SP4_RS01875 786ee17a8d3d2487d4209da1dc793400 200 SUPERFAMILY SSF55874 5 105 1.01E-19 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS01875 786ee17a8d3d2487d4209da1dc793400 200 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 5 107 1.5E-12 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS01875 786ee17a8d3d2487d4209da1dc793400 200 SMART SM00387 4 108 2.4E-8 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS01875 786ee17a8d3d2487d4209da1dc793400 200 Gene3D G3DSA:3.30.565.10 5 108 6.8E-19 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS01875 786ee17a8d3d2487d4209da1dc793400 200 PANTHER PTHR24423 8 114 1.4E-12 T 22-04-2016 L21SP4_RS01875 786ee17a8d3d2487d4209da1dc793400 200 PRINTS PR00344 Bacterial sensor protein C-terminal signature 92 105 1.5E-6 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS01875 786ee17a8d3d2487d4209da1dc793400 200 PRINTS PR00344 Bacterial sensor protein C-terminal signature 68 86 1.5E-6 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS01875 786ee17a8d3d2487d4209da1dc793400 200 PRINTS PR00344 Bacterial sensor protein C-terminal signature 35 49 1.5E-6 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS11470 acd228cdf40e2cb2ed3169454019d2d6 185 PANTHER PTHR18895:SF60 19 183 2.2E-30 T 22-04-2016 L21SP4_RS11470 acd228cdf40e2cb2ed3169454019d2d6 185 SUPERFAMILY SSF53335 1 178 1.09E-37 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS11470 acd228cdf40e2cb2ed3169454019d2d6 185 Gene3D G3DSA:3.40.50.150 1 182 6.1E-50 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS11470 acd228cdf40e2cb2ed3169454019d2d6 185 Pfam PF03602 Conserved hypothetical protein 95 1 178 1.2E-44 T 22-04-2016 L21SP4_RS11470 acd228cdf40e2cb2ed3169454019d2d6 185 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 116 122 - T 22-04-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 L21SP4_RS11470 acd228cdf40e2cb2ed3169454019d2d6 185 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 2 179 1.0E-38 T 22-04-2016 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 L21SP4_RS11470 acd228cdf40e2cb2ed3169454019d2d6 185 PANTHER PTHR18895 19 183 2.2E-30 T 22-04-2016 L21SP4_RS11470 acd228cdf40e2cb2ed3169454019d2d6 185 PIRSF PIRSF004553 1 182 5.4E-49 T 22-04-2016 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 L21SP4_RS03175 1597a32a3e5774eea4f63cad86bf56e7 482 TIGRFAM TIGR00873 gnd: 6-phosphogluconate dehydrogenase (decarboxylating) 4 469 6.4E-235 T 22-04-2016 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 L21SP4_RS03175 1597a32a3e5774eea4f63cad86bf56e7 482 Gene3D G3DSA:1.20.5.320 435 481 2.3E-26 T 22-04-2016 IPR012284 6-phosphogluconate dehydrogenase, domain 3 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 L21SP4_RS03175 1597a32a3e5774eea4f63cad86bf56e7 482 SUPERFAMILY SSF48179 177 472 8.93E-132 T 22-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 L21SP4_RS03175 1597a32a3e5774eea4f63cad86bf56e7 482 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 168 196 1.3E-85 T 22-04-2016 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 L21SP4_RS03175 1597a32a3e5774eea4f63cad86bf56e7 482 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 356 378 1.3E-85 T 22-04-2016 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 L21SP4_RS03175 1597a32a3e5774eea4f63cad86bf56e7 482 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 3 26 1.3E-85 T 22-04-2016 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 L21SP4_RS03175 1597a32a3e5774eea4f63cad86bf56e7 482 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 119 144 1.3E-85 T 22-04-2016 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 L21SP4_RS03175 1597a32a3e5774eea4f63cad86bf56e7 482 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 249 276 1.3E-85 T 22-04-2016 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 L21SP4_RS03175 1597a32a3e5774eea4f63cad86bf56e7 482 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 66 95 1.3E-85 T 22-04-2016 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 L21SP4_RS03175 1597a32a3e5774eea4f63cad86bf56e7 482 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 253 265 - T 22-04-2016 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 L21SP4_RS03175 1597a32a3e5774eea4f63cad86bf56e7 482 Gene3D G3DSA:3.40.50.720 2 180 9.1E-58 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS03175 1597a32a3e5774eea4f63cad86bf56e7 482 SUPERFAMILY SSF51735 3 175 9.42E-54 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS03175 1597a32a3e5774eea4f63cad86bf56e7 482 Gene3D G3DSA:1.10.1040.10 181 433 6.8E-121 T 22-04-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 L21SP4_RS03175 1597a32a3e5774eea4f63cad86bf56e7 482 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 179 468 1.2E-130 T 22-04-2016 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 L21SP4_RS03175 1597a32a3e5774eea4f63cad86bf56e7 482 SMART SM01350 179 469 4.6E-226 T 22-04-2016 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 L21SP4_RS03175 1597a32a3e5774eea4f63cad86bf56e7 482 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 4 169 1.3E-52 T 22-04-2016 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 L21SP4_RS03175 1597a32a3e5774eea4f63cad86bf56e7 482 PANTHER PTHR11811 3 482 0.0 T 22-04-2016 L21SP4_RS03175 1597a32a3e5774eea4f63cad86bf56e7 482 PIRSF PIRSF000109 1 477 1.2E-242 T 22-04-2016 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 L21SP4_RS00275 87122c9f0d831ea8aa70a5c231286dfd 279 PANTHER PTHR11807:SF17 10 262 8.4E-45 T 22-04-2016 L21SP4_RS00275 87122c9f0d831ea8aa70a5c231286dfd 279 PIRSF PIRSF006661 1 272 1.2E-78 T 22-04-2016 IPR005232 Conserved hypothetical protein CHP00268 L21SP4_RS00275 87122c9f0d831ea8aa70a5c231286dfd 279 SUPERFAMILY SSF52402 18 208 9.04E-34 T 22-04-2016 L21SP4_RS00275 87122c9f0d831ea8aa70a5c231286dfd 279 Gene3D G3DSA:3.40.50.620 16 171 4.1E-29 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP4_RS00275 87122c9f0d831ea8aa70a5c231286dfd 279 TIGRFAM TIGR00268 TIGR00268: TIGR00268 family protein 7 261 2.0E-61 T 22-04-2016 IPR005232 Conserved hypothetical protein CHP00268 L21SP4_RS00275 87122c9f0d831ea8aa70a5c231286dfd 279 Pfam PF02540 NAD synthase 5 87 1.0E-7 T 22-04-2016 IPR022310 NAD/GMP synthase L21SP4_RS00275 87122c9f0d831ea8aa70a5c231286dfd 279 PANTHER PTHR11807 10 262 8.4E-45 T 22-04-2016 L21SP4_RS05730 8eda9b6b4f59e27611fa864c844d830e 1246 SUPERFAMILY SSF103647 1090 1162 7.59E-5 T 22-04-2016 IPR028974 TSP type-3 repeat GO:0005509 L21SP4_RS05730 8eda9b6b4f59e27611fa864c844d830e 1246 SUPERFAMILY SSF50969 485 546 2.04E-8 T 22-04-2016 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like L21SP4_RS05730 8eda9b6b4f59e27611fa864c844d830e 1246 SUPERFAMILY SSF50969 776 864 2.04E-8 T 22-04-2016 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like L21SP4_RS05730 8eda9b6b4f59e27611fa864c844d830e 1246 SUPERFAMILY SSF50969 597 715 2.04E-8 T 22-04-2016 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like L21SP4_RS05730 8eda9b6b4f59e27611fa864c844d830e 1246 SUPERFAMILY SSF50969 810 1035 4.94E-10 T 22-04-2016 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like L21SP4_RS05730 8eda9b6b4f59e27611fa864c844d830e 1246 Gene3D G3DSA:2.60.40.670 296 373 4.1E-4 T 22-04-2016 IPR000601 PKD domain L21SP4_RS05730 8eda9b6b4f59e27611fa864c844d830e 1246 Pfam PF08309 LVIVD repeat 699 729 0.65 T 22-04-2016 IPR013211 LVIVD L21SP4_RS05730 8eda9b6b4f59e27611fa864c844d830e 1246 Pfam PF08309 LVIVD repeat 849 880 0.001 T 22-04-2016 IPR013211 LVIVD L21SP4_RS05730 8eda9b6b4f59e27611fa864c844d830e 1246 Pfam PF08309 LVIVD repeat 559 590 9.5E-5 T 22-04-2016 IPR013211 LVIVD L21SP4_RS05730 8eda9b6b4f59e27611fa864c844d830e 1246 Pfam PF08309 LVIVD repeat 509 542 0.013 T 22-04-2016 IPR013211 LVIVD L21SP4_RS05730 8eda9b6b4f59e27611fa864c844d830e 1246 Pfam PF08309 LVIVD repeat 599 633 6.1E-6 T 22-04-2016 IPR013211 LVIVD L21SP4_RS05730 8eda9b6b4f59e27611fa864c844d830e 1246 Pfam PF08309 LVIVD repeat 468 502 9.3E-4 T 22-04-2016 IPR013211 LVIVD L21SP4_RS03155 6f8981e61dbf4c6458cc5956a1e459d7 361 Pfam PF13377 Periplasmic binding protein-like domain 208 360 9.6E-28 T 22-04-2016 L21SP4_RS03155 6f8981e61dbf4c6458cc5956a1e459d7 361 Pfam PF00356 Bacterial regulatory proteins, lacI family 46 91 3.1E-9 T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 L21SP4_RS03155 6f8981e61dbf4c6458cc5956a1e459d7 361 Gene3D G3DSA:3.40.50.2300 211 360 6.3E-37 T 22-04-2016 L21SP4_RS03155 6f8981e61dbf4c6458cc5956a1e459d7 361 Gene3D G3DSA:1.10.260.40 44 96 7.4E-19 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 L21SP4_RS03155 6f8981e61dbf4c6458cc5956a1e459d7 361 PANTHER PTHR30146 41 360 1.7E-66 T 22-04-2016 L21SP4_RS03155 6f8981e61dbf4c6458cc5956a1e459d7 361 Gene3D G3DSA:3.40.50.2300 97 210 1.5E-24 T 22-04-2016 L21SP4_RS03155 6f8981e61dbf4c6458cc5956a1e459d7 361 SUPERFAMILY SSF47413 43 99 1.13E-11 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 L21SP4_RS03155 6f8981e61dbf4c6458cc5956a1e459d7 361 PANTHER PTHR30146:SF48 41 360 1.7E-66 T 22-04-2016 L21SP4_RS03155 6f8981e61dbf4c6458cc5956a1e459d7 361 SUPERFAMILY SSF53822 103 360 4.12E-48 T 22-04-2016 IPR028082 Periplasmic binding protein-like I L21SP4_RS03155 6f8981e61dbf4c6458cc5956a1e459d7 361 SMART SM00354 41 114 6.9E-18 T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 L21SP4_RS03140 2755995f1539403f604aac4bd325b3f1 410 Pfam PF01609 Transposase DDE domain 130 346 4.3E-24 T 22-04-2016 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 L21SP4_RS03140 2755995f1539403f604aac4bd325b3f1 410 Gene3D G3DSA:3.90.350.10 293 321 1.1E-4 T 22-04-2016 IPR014736 Transposase, Tn5-like, core L21SP4_RS03140 2755995f1539403f604aac4bd325b3f1 410 PANTHER PTHR33258 8 382 1.3E-35 T 22-04-2016 L21SP4_RS03140 2755995f1539403f604aac4bd325b3f1 410 Pfam PF14294 Domain of unknown function (DUF4372) 10 71 1.2E-11 T 22-04-2016 IPR025399 Domain of unknown function DUF4372 L21SP4_RS03140 2755995f1539403f604aac4bd325b3f1 410 PANTHER PTHR33258:SF1 8 382 1.3E-35 T 22-04-2016 L21SP4_RS03140 2755995f1539403f604aac4bd325b3f1 410 SUPERFAMILY SSF53098 128 367 1.21E-22 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS11090 b3e172e933b5d5172e2d0adebac4f492 318 Gene3D G3DSA:3.90.25.10 177 317 4.2E-55 T 22-04-2016 L21SP4_RS11090 b3e172e933b5d5172e2d0adebac4f492 318 Pfam PF16363 GDP-mannose 4,6 dehydratase 13 309 3.8E-55 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS11090 b3e172e933b5d5172e2d0adebac4f492 318 Gene3D G3DSA:3.40.50.720 4 176 2.0E-60 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS11090 b3e172e933b5d5172e2d0adebac4f492 318 SUPERFAMILY SSF51735 5 316 2.08E-91 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS11090 b3e172e933b5d5172e2d0adebac4f492 318 PANTHER PTHR10366:SF399 10 317 1.5E-157 T 22-04-2016 L21SP4_RS11090 b3e172e933b5d5172e2d0adebac4f492 318 PANTHER PTHR10366 10 317 1.5E-157 T 22-04-2016 L21SP4_RS06815 699f7a45c3bd87159884dc2fae21704b 1174 Gene3D G3DSA:3.40.50.880 821 886 1.6E-4 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like L21SP4_RS06815 699f7a45c3bd87159884dc2fae21704b 1174 Gene3D G3DSA:2.60.120.200 20 221 1.3E-19 T 22-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP4_RS06815 699f7a45c3bd87159884dc2fae21704b 1174 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 72 220 3.7E-15 T 22-04-2016 L21SP4_RS06815 699f7a45c3bd87159884dc2fae21704b 1174 SUPERFAMILY SSF52317 801 885 2.9E-6 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like L21SP4_RS06815 699f7a45c3bd87159884dc2fae21704b 1174 SUPERFAMILY SSF49899 20 231 4.55E-23 T 22-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP4_RS03685 1a53cd6fbb61cf5c1ecfb6a4f953b773 314 PANTHER PTHR23416:SF65 55 296 5.4E-81 T 22-04-2016 L21SP4_RS03685 1a53cd6fbb61cf5c1ecfb6a4f953b773 314 PANTHER PTHR23416 55 296 5.4E-81 T 22-04-2016 L21SP4_RS03685 1a53cd6fbb61cf5c1ecfb6a4f953b773 314 SUPERFAMILY SSF51161 115 296 7.49E-41 T 22-04-2016 IPR011004 Trimeric LpxA-like L21SP4_RS03685 1a53cd6fbb61cf5c1ecfb6a4f953b773 314 Pfam PF06426 Serine acetyltransferase, N-terminal 106 161 8.3E-5 T 22-04-2016 IPR010493 Serine acetyltransferase, N-terminal GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|UniPathway: UPA00136 L21SP4_RS03685 1a53cd6fbb61cf5c1ecfb6a4f953b773 314 Gene3D G3DSA:1.10.3130.10 36 188 2.8E-30 T 22-04-2016 L21SP4_RS03685 1a53cd6fbb61cf5c1ecfb6a4f953b773 314 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 197 233 3.5E-4 T 22-04-2016 IPR001451 Hexapeptide repeat L21SP4_RS03685 1a53cd6fbb61cf5c1ecfb6a4f953b773 314 Gene3D G3DSA:2.160.10.10 189 300 5.5E-26 T 22-04-2016 L21SP4_RS10090 88bada00916ccb1ea1e68067db72bdd8 325 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 2 320 2.7E-118 T 22-04-2016 IPR005886 UDP-glucose 4-epimerase GalE GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|UniPathway: UPA00214 L21SP4_RS10090 88bada00916ccb1ea1e68067db72bdd8 325 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 246 2.1E-55 T 22-04-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 L21SP4_RS10090 88bada00916ccb1ea1e68067db72bdd8 325 PANTHER PTHR10366:SF39 2 321 3.8E-113 T 22-04-2016 L21SP4_RS10090 88bada00916ccb1ea1e68067db72bdd8 325 PANTHER PTHR10366 2 321 3.8E-113 T 22-04-2016 L21SP4_RS10090 88bada00916ccb1ea1e68067db72bdd8 325 Gene3D G3DSA:3.40.50.720 1 170 1.7E-46 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS10090 88bada00916ccb1ea1e68067db72bdd8 325 SUPERFAMILY SSF51735 1 321 6.18E-94 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS10090 88bada00916ccb1ea1e68067db72bdd8 325 Gene3D G3DSA:3.90.25.10 171 323 8.4E-49 T 22-04-2016 L21SP4_RS02480 44b06f21b11f6b7bd6d2a226e8f6e5b7 551 TIGRFAM TIGR00717 rpsA: ribosomal protein bS1 12 519 2.5E-196 T 22-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 L21SP4_RS02480 44b06f21b11f6b7bd6d2a226e8f6e5b7 551 Gene3D G3DSA:2.40.50.140 191 271 1.1E-29 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold L21SP4_RS02480 44b06f21b11f6b7bd6d2a226e8f6e5b7 551 Gene3D G3DSA:2.40.50.140 363 443 2.6E-29 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold L21SP4_RS02480 44b06f21b11f6b7bd6d2a226e8f6e5b7 551 SUPERFAMILY SSF50249 356 446 2.72E-24 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold L21SP4_RS02480 44b06f21b11f6b7bd6d2a226e8f6e5b7 551 SUPERFAMILY SSF50249 254 358 3.79E-27 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold L21SP4_RS02480 44b06f21b11f6b7bd6d2a226e8f6e5b7 551 SUPERFAMILY SSF50249 189 276 8.95E-27 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold L21SP4_RS02480 44b06f21b11f6b7bd6d2a226e8f6e5b7 551 SUPERFAMILY SSF50249 15 111 2.16E-16 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold L21SP4_RS02480 44b06f21b11f6b7bd6d2a226e8f6e5b7 551 Pfam PF00575 S1 RNA binding domain 102 170 4.6E-11 T 22-04-2016 IPR003029 S1 domain GO:0003676 L21SP4_RS02480 44b06f21b11f6b7bd6d2a226e8f6e5b7 551 Pfam PF00575 S1 RNA binding domain 274 346 2.3E-19 T 22-04-2016 IPR003029 S1 domain GO:0003676 L21SP4_RS02480 44b06f21b11f6b7bd6d2a226e8f6e5b7 551 Pfam PF00575 S1 RNA binding domain 446 519 5.8E-22 T 22-04-2016 IPR003029 S1 domain GO:0003676 L21SP4_RS02480 44b06f21b11f6b7bd6d2a226e8f6e5b7 551 Pfam PF00575 S1 RNA binding domain 20 85 1.5E-6 T 22-04-2016 IPR003029 S1 domain GO:0003676 L21SP4_RS02480 44b06f21b11f6b7bd6d2a226e8f6e5b7 551 Pfam PF00575 S1 RNA binding domain 188 259 1.9E-17 T 22-04-2016 IPR003029 S1 domain GO:0003676 L21SP4_RS02480 44b06f21b11f6b7bd6d2a226e8f6e5b7 551 Pfam PF00575 S1 RNA binding domain 361 433 4.8E-18 T 22-04-2016 IPR003029 S1 domain GO:0003676 L21SP4_RS02480 44b06f21b11f6b7bd6d2a226e8f6e5b7 551 PANTHER PTHR10724 10 513 9.9E-231 T 22-04-2016 L21SP4_RS02480 44b06f21b11f6b7bd6d2a226e8f6e5b7 551 Gene3D G3DSA:2.40.50.140 8 86 7.6E-10 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold L21SP4_RS02480 44b06f21b11f6b7bd6d2a226e8f6e5b7 551 Gene3D G3DSA:2.40.50.140 444 522 1.4E-30 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold L21SP4_RS02480 44b06f21b11f6b7bd6d2a226e8f6e5b7 551 SUPERFAMILY SSF50249 102 184 4.55E-17 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold L21SP4_RS02480 44b06f21b11f6b7bd6d2a226e8f6e5b7 551 Gene3D G3DSA:2.40.50.140 94 171 2.5E-18 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold L21SP4_RS02480 44b06f21b11f6b7bd6d2a226e8f6e5b7 551 Gene3D G3DSA:2.40.50.140 272 347 4.1E-28 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold L21SP4_RS02480 44b06f21b11f6b7bd6d2a226e8f6e5b7 551 PRINTS PR00681 Ribosomal protein S1 signature 23 41 3.6E-70 T 22-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 L21SP4_RS02480 44b06f21b11f6b7bd6d2a226e8f6e5b7 551 PRINTS PR00681 Ribosomal protein S1 signature 125 142 3.6E-70 T 22-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 L21SP4_RS02480 44b06f21b11f6b7bd6d2a226e8f6e5b7 551 PRINTS PR00681 Ribosomal protein S1 signature 289 308 3.6E-70 T 22-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 L21SP4_RS02480 44b06f21b11f6b7bd6d2a226e8f6e5b7 551 PRINTS PR00681 Ribosomal protein S1 signature 107 123 3.6E-70 T 22-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 L21SP4_RS02480 44b06f21b11f6b7bd6d2a226e8f6e5b7 551 PRINTS PR00681 Ribosomal protein S1 signature 154 174 3.6E-70 T 22-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 L21SP4_RS02480 44b06f21b11f6b7bd6d2a226e8f6e5b7 551 PRINTS PR00681 Ribosomal protein S1 signature 41 55 3.6E-70 T 22-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 L21SP4_RS02480 44b06f21b11f6b7bd6d2a226e8f6e5b7 551 PRINTS PR00681 Ribosomal protein S1 signature 329 347 3.6E-70 T 22-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 L21SP4_RS02480 44b06f21b11f6b7bd6d2a226e8f6e5b7 551 PRINTS PR00681 Ribosomal protein S1 signature 83 102 3.6E-70 T 22-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 L21SP4_RS02480 44b06f21b11f6b7bd6d2a226e8f6e5b7 551 PRINTS PR00681 Ribosomal protein S1 signature 211 232 3.6E-70 T 22-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 L21SP4_RS02480 44b06f21b11f6b7bd6d2a226e8f6e5b7 551 SUPERFAMILY SSF50249 428 530 6.04E-28 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold L21SP4_RS02480 44b06f21b11f6b7bd6d2a226e8f6e5b7 551 PANTHER PTHR10724:SF6 10 513 9.9E-231 T 22-04-2016 L21SP4_RS02480 44b06f21b11f6b7bd6d2a226e8f6e5b7 551 SMART SM00316 21 86 1.8E-6 T 22-04-2016 IPR022967 RNA-binding domain, S1 L21SP4_RS02480 44b06f21b11f6b7bd6d2a226e8f6e5b7 551 SMART SM00316 448 519 2.1E-27 T 22-04-2016 IPR022967 RNA-binding domain, S1 L21SP4_RS02480 44b06f21b11f6b7bd6d2a226e8f6e5b7 551 SMART SM00316 274 346 9.4E-26 T 22-04-2016 IPR022967 RNA-binding domain, S1 L21SP4_RS02480 44b06f21b11f6b7bd6d2a226e8f6e5b7 551 SMART SM00316 189 259 6.9E-26 T 22-04-2016 IPR022967 RNA-binding domain, S1 L21SP4_RS02480 44b06f21b11f6b7bd6d2a226e8f6e5b7 551 SMART SM00316 361 433 1.0E-26 T 22-04-2016 IPR022967 RNA-binding domain, S1 L21SP4_RS02480 44b06f21b11f6b7bd6d2a226e8f6e5b7 551 SMART SM00316 102 170 1.9E-9 T 22-04-2016 IPR022967 RNA-binding domain, S1 L21SP4_RS08900 81af625ec8e4a389e5867721ef6d9d6b 482 Pfam PF00152 tRNA synthetases class II (D, K and N) 149 479 3.1E-72 T 22-04-2016 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 L21SP4_RS08900 81af625ec8e4a389e5867721ef6d9d6b 482 SUPERFAMILY SSF55681 148 480 9.0E-100 T 22-04-2016 L21SP4_RS08900 81af625ec8e4a389e5867721ef6d9d6b 482 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 16 482 37.626 T 22-04-2016 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6 L21SP4_RS08900 81af625ec8e4a389e5867721ef6d9d6b 482 Pfam PF01336 OB-fold nucleic acid binding domain 55 132 2.5E-13 T 22-04-2016 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 L21SP4_RS08900 81af625ec8e4a389e5867721ef6d9d6b 482 Gene3D G3DSA:3.30.930.10 143 479 1.2E-107 T 22-04-2016 L21SP4_RS08900 81af625ec8e4a389e5867721ef6d9d6b 482 PRINTS PR00982 Lysyl-tRNA synthetase signature 230 243 7.1E-32 T 22-04-2016 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 L21SP4_RS08900 81af625ec8e4a389e5867721ef6d9d6b 482 PRINTS PR00982 Lysyl-tRNA synthetase signature 201 217 7.1E-32 T 22-04-2016 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 L21SP4_RS08900 81af625ec8e4a389e5867721ef6d9d6b 482 PRINTS PR00982 Lysyl-tRNA synthetase signature 248 265 7.1E-32 T 22-04-2016 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 L21SP4_RS08900 81af625ec8e4a389e5867721ef6d9d6b 482 PRINTS PR00982 Lysyl-tRNA synthetase signature 370 386 7.1E-32 T 22-04-2016 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 L21SP4_RS08900 81af625ec8e4a389e5867721ef6d9d6b 482 PRINTS PR00982 Lysyl-tRNA synthetase signature 185 195 7.1E-32 T 22-04-2016 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 L21SP4_RS08900 81af625ec8e4a389e5867721ef6d9d6b 482 PANTHER PTHR22594:SF4 1 480 2.9E-205 T 22-04-2016 L21SP4_RS08900 81af625ec8e4a389e5867721ef6d9d6b 482 SUPERFAMILY SSF50249 9 141 6.0E-32 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold L21SP4_RS08900 81af625ec8e4a389e5867721ef6d9d6b 482 PANTHER PTHR22594 1 480 2.9E-205 T 22-04-2016 IPR018150 Aminoacyl-tRNA synthetase, class II (D/K/N)-like GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 L21SP4_RS08900 81af625ec8e4a389e5867721ef6d9d6b 482 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 11 480 1.6E-158 T 22-04-2016 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6 L21SP4_RS08900 81af625ec8e4a389e5867721ef6d9d6b 482 Gene3D G3DSA:2.40.50.140 12 141 1.1E-34 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold L21SP4_RS03415 b1a96523957a7655a75da49334c4dabd 509 PANTHER PTHR35861 2 509 4.4E-57 T 22-04-2016 L21SP4_RS03415 b1a96523957a7655a75da49334c4dabd 509 PANTHER PTHR35861:SF1 2 509 4.4E-57 T 22-04-2016 L21SP4_RS03415 b1a96523957a7655a75da49334c4dabd 509 Pfam PF04984 Phage tail sheath protein 1 498 1.9E-72 T 22-04-2016 IPR007067 Tail sheath protein L21SP4_RS02495 cdf46a8b8f20a7013c7e7c75e5b0f00a 290 SUPERFAMILY SSF53223 4 107 8.06E-30 T 22-04-2016 L21SP4_RS02495 cdf46a8b8f20a7013c7e7c75e5b0f00a 290 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 13 95 2.3E-25 T 22-04-2016 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163|UniPathway: UPA00053 L21SP4_RS02495 cdf46a8b8f20a7013c7e7c75e5b0f00a 290 Gene3D G3DSA:3.40.192.10 4 112 1.3E-37 T 22-04-2016 L21SP4_RS02495 cdf46a8b8f20a7013c7e7c75e5b0f00a 290 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 8 282 31.331 T 22-04-2016 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163|UniPathway: UPA00053 L21SP4_RS02495 cdf46a8b8f20a7013c7e7c75e5b0f00a 290 Gene3D G3DSA:3.40.50.720 113 283 2.2E-43 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS02495 cdf46a8b8f20a7013c7e7c75e5b0f00a 290 PANTHER PTHR21089 8 288 2.3E-71 T 22-04-2016 L21SP4_RS02495 cdf46a8b8f20a7013c7e7c75e5b0f00a 290 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 11 283 5.7E-61 T 22-04-2016 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163|UniPathway: UPA00053 L21SP4_RS02495 cdf46a8b8f20a7013c7e7c75e5b0f00a 290 SUPERFAMILY SSF51735 108 283 1.78E-34 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS02495 cdf46a8b8f20a7013c7e7c75e5b0f00a 290 PANTHER PTHR21089:SF8 8 288 2.3E-71 T 22-04-2016 L21SP4_RS08020 a445e0cca8d042561ea888c92d58dee1 328 PANTHER PTHR10366 8 323 4.9E-97 T 22-04-2016 L21SP4_RS08020 a445e0cca8d042561ea888c92d58dee1 328 PANTHER PTHR10366:SF469 8 323 4.9E-97 T 22-04-2016 L21SP4_RS08020 a445e0cca8d042561ea888c92d58dee1 328 Gene3D G3DSA:3.90.25.10 179 304 5.5E-34 T 22-04-2016 L21SP4_RS08020 a445e0cca8d042561ea888c92d58dee1 328 TIGRFAM TIGR02197 heptose_epim: ADP-glyceromanno-heptose 6-epimerase 10 322 6.6E-121 T 22-04-2016 IPR011912 ADP-L-glycero-D-manno-heptose-6-epimerase GO:0005975|GO:0008712|GO:0050661 KEGG: 00540+5.1.3.20|UniPathway: UPA00356 L21SP4_RS08020 a445e0cca8d042561ea888c92d58dee1 328 Pfam PF01370 NAD dependent epimerase/dehydratase family 10 250 9.8E-43 T 22-04-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 L21SP4_RS08020 a445e0cca8d042561ea888c92d58dee1 328 SUPERFAMILY SSF51735 7 323 2.41E-67 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS08020 a445e0cca8d042561ea888c92d58dee1 328 Gene3D G3DSA:3.40.50.720 8 178 1.8E-25 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS08065 6a74ed00fe3e87ee6105fb40eecaca4c 816 SUPERFAMILY SSF55874 478 648 3.54E-46 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS08065 6a74ed00fe3e87ee6105fb40eecaca4c 816 Gene3D G3DSA:3.40.50.2300 678 812 4.0E-42 T 22-04-2016 L21SP4_RS08065 6a74ed00fe3e87ee6105fb40eecaca4c 816 Gene3D G3DSA:3.30.450.20 265 377 1.2E-13 T 22-04-2016 L21SP4_RS08065 6a74ed00fe3e87ee6105fb40eecaca4c 816 Pfam PF17152 Periplasmic sensor domain 54 156 6.4E-19 T 22-04-2016 IPR033417 Periplasmic sensor domain CHASE8 UniPathway: UPA00599 L21SP4_RS08065 6a74ed00fe3e87ee6105fb40eecaca4c 816 PANTHER PTHR24423 420 795 1.7E-163 T 22-04-2016 L21SP4_RS08065 6a74ed00fe3e87ee6105fb40eecaca4c 816 PANTHER PTHR24423 12 37 1.7E-163 T 22-04-2016 L21SP4_RS08065 6a74ed00fe3e87ee6105fb40eecaca4c 816 PANTHER PTHR24423 238 398 1.7E-163 T 22-04-2016 L21SP4_RS08065 6a74ed00fe3e87ee6105fb40eecaca4c 816 PRINTS PR00344 Bacterial sensor protein C-terminal signature 636 649 7.1E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS08065 6a74ed00fe3e87ee6105fb40eecaca4c 816 PRINTS PR00344 Bacterial sensor protein C-terminal signature 612 630 7.1E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS08065 6a74ed00fe3e87ee6105fb40eecaca4c 816 PRINTS PR00344 Bacterial sensor protein C-terminal signature 577 591 7.1E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS08065 6a74ed00fe3e87ee6105fb40eecaca4c 816 PRINTS PR00344 Bacterial sensor protein C-terminal signature 595 605 7.1E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS08065 6a74ed00fe3e87ee6105fb40eecaca4c 816 Pfam PF00672 HAMP domain 175 243 4.2E-12 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 L21SP4_RS08065 6a74ed00fe3e87ee6105fb40eecaca4c 816 Gene3D G3DSA:3.30.565.10 475 653 1.5E-47 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS08065 6a74ed00fe3e87ee6105fb40eecaca4c 816 SUPERFAMILY SSF55785 259 369 4.19E-13 T 22-04-2016 IPR000014 PAS domain L21SP4_RS08065 6a74ed00fe3e87ee6105fb40eecaca4c 816 SUPERFAMILY SSF158472 194 244 8.63E-8 T 22-04-2016 L21SP4_RS08065 6a74ed00fe3e87ee6105fb40eecaca4c 816 Pfam PF13188 PAS domain 273 320 1.2E-4 T 22-04-2016 IPR000014 PAS domain L21SP4_RS08065 6a74ed00fe3e87ee6105fb40eecaca4c 816 Pfam PF00512 His Kinase A (phospho-acceptor) domain 424 489 1.6E-18 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS08065 6a74ed00fe3e87ee6105fb40eecaca4c 816 SUPERFAMILY SSF52172 678 797 6.55E-40 T 22-04-2016 IPR011006 CheY-like superfamily L21SP4_RS08065 6a74ed00fe3e87ee6105fb40eecaca4c 816 SMART SM00387 536 652 5.1E-44 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS08065 6a74ed00fe3e87ee6105fb40eecaca4c 816 SMART SM00304 194 247 6.2E-8 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 L21SP4_RS08065 6a74ed00fe3e87ee6105fb40eecaca4c 816 SMART SM00388 424 489 4.7E-22 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS08065 6a74ed00fe3e87ee6105fb40eecaca4c 816 Gene3D G3DSA:1.10.287.130 415 474 1.2E-16 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS08065 6a74ed00fe3e87ee6105fb40eecaca4c 816 SMART SM00448 680 793 2.4E-38 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 L21SP4_RS08065 6a74ed00fe3e87ee6105fb40eecaca4c 816 SUPERFAMILY SSF47384 411 490 1.41E-21 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS08065 6a74ed00fe3e87ee6105fb40eecaca4c 816 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 536 650 4.8E-31 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS08065 6a74ed00fe3e87ee6105fb40eecaca4c 816 Pfam PF00072 Response regulator receiver domain 682 793 1.1E-27 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 L21SP4_RS08065 6a74ed00fe3e87ee6105fb40eecaca4c 816 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 268 390 4.7E-12 T 22-04-2016 IPR000014 PAS domain L21SP4_RS03880 dba88257da753f3d17bae0c143df1c0b 783 ProDom PD004169 PRECURSOR CYSTEINE STREPTOCOCCAL STREPTOPAIN PROTEINASE PROTEASE THIOL B STREPTOCOCCUS EXOTOXIN 195 393 3.0E-17 T 22-04-2016 IPR000200 Peptidase C10, streptopain GO:0006508|GO:0008234 L21SP4_RS03880 dba88257da753f3d17bae0c143df1c0b 783 SUPERFAMILY SSF49899 465 597 1.04E-5 T 22-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP4_RS03880 dba88257da753f3d17bae0c143df1c0b 783 SUPERFAMILY SSF54001 27 404 9.81E-54 T 22-04-2016 L21SP4_RS03880 dba88257da753f3d17bae0c143df1c0b 783 Pfam PF13734 Spi protease inhibitor 26 124 8.7E-6 T 22-04-2016 IPR025896 Spi protease inhibitor L21SP4_RS03880 dba88257da753f3d17bae0c143df1c0b 783 Pfam PF01640 Peptidase C10 family 195 392 8.0E-41 T 22-04-2016 IPR000200 Peptidase C10, streptopain GO:0006508|GO:0008234 L21SP4_RS03880 dba88257da753f3d17bae0c143df1c0b 783 PRINTS PR00797 Streptopain (C10) cysteine protease family signature 378 399 1.7E-15 T 22-04-2016 IPR000200 Peptidase C10, streptopain GO:0006508|GO:0008234 L21SP4_RS03880 dba88257da753f3d17bae0c143df1c0b 783 PRINTS PR00797 Streptopain (C10) cysteine protease family signature 288 304 1.7E-15 T 22-04-2016 IPR000200 Peptidase C10, streptopain GO:0006508|GO:0008234 L21SP4_RS03880 dba88257da753f3d17bae0c143df1c0b 783 PRINTS PR00797 Streptopain (C10) cysteine protease family signature 216 240 1.7E-15 T 22-04-2016 IPR000200 Peptidase C10, streptopain GO:0006508|GO:0008234 L21SP4_RS00585 77b97c3fcfe6bb189b9c9c83efcec0fb 281 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 3 247 9.3E-30 T 22-04-2016 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain L21SP4_RS00585 77b97c3fcfe6bb189b9c9c83efcec0fb 281 Gene3D G3DSA:3.30.70.20 59 106 1.3E-15 T 22-04-2016 L21SP4_RS00585 77b97c3fcfe6bb189b9c9c83efcec0fb 281 PANTHER PTHR13696 1 281 1.7E-62 T 22-04-2016 L21SP4_RS00585 77b97c3fcfe6bb189b9c9c83efcec0fb 281 Gene3D G3DSA:3.40.50.300 107 269 5.3E-47 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS00585 77b97c3fcfe6bb189b9c9c83efcec0fb 281 Gene3D G3DSA:3.40.50.300 1 55 5.3E-47 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS00585 77b97c3fcfe6bb189b9c9c83efcec0fb 281 SUPERFAMILY SSF52540 1 49 4.45E-32 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS00585 77b97c3fcfe6bb189b9c9c83efcec0fb 281 SUPERFAMILY SSF52540 109 269 4.45E-32 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS00585 77b97c3fcfe6bb189b9c9c83efcec0fb 281 PANTHER PTHR13696:SF64 1 281 1.7E-62 T 22-04-2016 L21SP4_RS00585 77b97c3fcfe6bb189b9c9c83efcec0fb 281 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 99 110 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site L21SP4_RS00585 77b97c3fcfe6bb189b9c9c83efcec0fb 281 SUPERFAMILY SSF54862 55 119 9.99E-19 T 22-04-2016 L21SP4_RS00585 77b97c3fcfe6bb189b9c9c83efcec0fb 281 Pfam PF00037 4Fe-4S binding domain 63 85 1.7E-6 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain L21SP4_RS00585 77b97c3fcfe6bb189b9c9c83efcec0fb 281 Pfam PF00037 4Fe-4S binding domain 94 114 7.5E-5 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain L21SP4_RS10860 cb9cccb3b82de587b381b9f8562f85b3 324 PANTHER PTHR10108 110 301 6.5E-38 T 22-04-2016 L21SP4_RS10860 cb9cccb3b82de587b381b9f8562f85b3 324 Gene3D G3DSA:3.40.50.150 111 293 2.2E-43 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS10860 cb9cccb3b82de587b381b9f8562f85b3 324 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 27 38 1.5E-14 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 L21SP4_RS10860 cb9cccb3b82de587b381b9f8562f85b3 324 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 40 55 1.5E-14 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 L21SP4_RS10860 cb9cccb3b82de587b381b9f8562f85b3 324 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 8 23 1.5E-14 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 L21SP4_RS10860 cb9cccb3b82de587b381b9f8562f85b3 324 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 55 70 1.5E-14 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 L21SP4_RS10860 cb9cccb3b82de587b381b9f8562f85b3 324 Pfam PF12840 Helix-turn-helix domain 6 63 2.8E-13 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS10860 cb9cccb3b82de587b381b9f8562f85b3 324 Pfam PF08241 Methyltransferase domain 150 246 2.9E-25 T 22-04-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 L21SP4_RS10860 cb9cccb3b82de587b381b9f8562f85b3 324 SMART SM00418 6 84 5.0E-16 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 L21SP4_RS10860 cb9cccb3b82de587b381b9f8562f85b3 324 SUPERFAMILY SSF46785 2 127 3.25E-22 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS10860 cb9cccb3b82de587b381b9f8562f85b3 324 Gene3D G3DSA:1.10.10.10 4 72 1.8E-21 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS10860 cb9cccb3b82de587b381b9f8562f85b3 324 SUPERFAMILY SSF53335 98 306 1.13E-44 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS11250 1802b86221d8e300de8433aa3d52a162 713 PANTHER PTHR11695 92 378 8.6E-49 T 22-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 L21SP4_RS11250 1802b86221d8e300de8433aa3d52a162 713 SMART SM00829 9 366 6.6E-5 T 22-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 L21SP4_RS11250 1802b86221d8e300de8433aa3d52a162 713 Pfam PF00107 Zinc-binding dehydrogenase 179 298 8.6E-21 T 22-04-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 L21SP4_RS11250 1802b86221d8e300de8433aa3d52a162 713 Gene3D G3DSA:3.90.180.10 86 173 4.4E-19 T 22-04-2016 IPR011032 GroES-like L21SP4_RS11250 1802b86221d8e300de8433aa3d52a162 713 Gene3D G3DSA:3.90.180.10 12 52 4.4E-19 T 22-04-2016 IPR011032 GroES-like L21SP4_RS11250 1802b86221d8e300de8433aa3d52a162 713 Gene3D G3DSA:3.40.50.720 394 533 5.6E-34 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS11250 1802b86221d8e300de8433aa3d52a162 713 SUPERFAMILY SSF51735 149 297 9.11E-31 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS11250 1802b86221d8e300de8433aa3d52a162 713 SUPERFAMILY SSF51735 390 562 1.74E-37 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS11250 1802b86221d8e300de8433aa3d52a162 713 Gene3D G3DSA:3.30.360.10 534 695 3.5E-18 T 22-04-2016 L21SP4_RS11250 1802b86221d8e300de8433aa3d52a162 713 Gene3D G3DSA:3.40.50.720 174 287 3.6E-31 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS11250 1802b86221d8e300de8433aa3d52a162 713 SUPERFAMILY SSF50129 11 53 2.7E-17 T 22-04-2016 IPR011032 GroES-like L21SP4_RS11250 1802b86221d8e300de8433aa3d52a162 713 SUPERFAMILY SSF50129 85 178 2.7E-17 T 22-04-2016 IPR011032 GroES-like L21SP4_RS11250 1802b86221d8e300de8433aa3d52a162 713 SUPERFAMILY SSF55347 538 687 1.64E-14 T 22-04-2016 L21SP4_RS11250 1802b86221d8e300de8433aa3d52a162 713 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 400 521 2.5E-18 T 22-04-2016 IPR000683 Oxidoreductase, N-terminal GO:0016491 L21SP4_RS05970 101a84026000d7c6b5b93305bc53b4b3 135 Gene3D G3DSA:3.40.50.1010 4 131 1.1E-6 T 22-04-2016 IPR029060 PIN domain-like L21SP4_RS05970 101a84026000d7c6b5b93305bc53b4b3 135 Pfam PF01850 PIN domain 5 124 4.6E-5 T 22-04-2016 IPR002716 PIN domain L21SP4_RS05970 101a84026000d7c6b5b93305bc53b4b3 135 SUPERFAMILY SSF88723 1 125 2.75E-8 T 22-04-2016 IPR029060 PIN domain-like L21SP4_RS07350 5385de9a3e7b3c2b14778d9da2b0cb55 111 PANTHER PTHR12599 7 111 1.3E-34 T 22-04-2016 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 L21SP4_RS07350 5385de9a3e7b3c2b14778d9da2b0cb55 111 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 21 108 9.2E-31 T 22-04-2016 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 L21SP4_RS07350 5385de9a3e7b3c2b14778d9da2b0cb55 111 SUPERFAMILY SSF55248 21 110 2.22E-31 T 22-04-2016 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 L21SP4_RS07350 5385de9a3e7b3c2b14778d9da2b0cb55 111 Gene3D G3DSA:3.30.1360.20 15 110 1.4E-31 T 22-04-2016 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 L21SP4_RS07350 5385de9a3e7b3c2b14778d9da2b0cb55 111 Hamap MF_00434 Putative pterin-4-alpha-carbinolamine dehydratase. 19 110 22.697 T 22-04-2016 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 L21SP4_RS03110 95917fb3ae2f19bffb84a4a2c21325e4 386 SUPERFAMILY SSF53756 68 385 3.89E-68 T 22-04-2016 L21SP4_RS03110 95917fb3ae2f19bffb84a4a2c21325e4 386 Gene3D G3DSA:3.40.50.2000 167 363 1.6E-27 T 22-04-2016 L21SP4_RS03110 95917fb3ae2f19bffb84a4a2c21325e4 386 Pfam PF00534 Glycosyl transferases group 1 196 363 7.1E-33 T 22-04-2016 IPR001296 Glycosyl transferase, family 1 L21SP4_RS03110 95917fb3ae2f19bffb84a4a2c21325e4 386 Pfam PF13439 Glycosyltransferase Family 4 91 183 1.6E-8 T 22-04-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain L21SP4_RS03110 95917fb3ae2f19bffb84a4a2c21325e4 386 PANTHER PTHR12526 91 385 2.4E-63 T 22-04-2016 L21SP4_RS07000 8055a3ba308ab30875926c64c65f8526 762 Gene3D G3DSA:3.40.50.920 636 759 1.2E-37 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 L21SP4_RS07000 8055a3ba308ab30875926c64c65f8526 762 Pfam PF00676 Dehydrogenase E1 component 78 399 2.2E-54 T 22-04-2016 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 L21SP4_RS07000 8055a3ba308ab30875926c64c65f8526 762 PANTHER PTHR11624 76 387 3.2E-179 T 22-04-2016 IPR033247 Transketolase family L21SP4_RS07000 8055a3ba308ab30875926c64c65f8526 762 PANTHER PTHR11624 430 762 3.2E-179 T 22-04-2016 IPR033247 Transketolase family L21SP4_RS07000 8055a3ba308ab30875926c64c65f8526 762 SMART SM00861 443 618 1.1E-65 T 22-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain L21SP4_RS07000 8055a3ba308ab30875926c64c65f8526 762 Pfam PF02779 Transketolase, pyrimidine binding domain 443 617 6.9E-51 T 22-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain L21SP4_RS07000 8055a3ba308ab30875926c64c65f8526 762 SUPERFAMILY SSF52518 153 413 5.79E-70 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold L21SP4_RS07000 8055a3ba308ab30875926c64c65f8526 762 SUPERFAMILY SSF52518 37 119 5.79E-70 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold L21SP4_RS07000 8055a3ba308ab30875926c64c65f8526 762 SUPERFAMILY SSF52922 626 762 3.14E-36 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 L21SP4_RS07000 8055a3ba308ab30875926c64c65f8526 762 Pfam PF02780 Transketolase, C-terminal domain 632 754 9.6E-33 T 22-04-2016 IPR033248 Transketolase, C-terminal domain L21SP4_RS07000 8055a3ba308ab30875926c64c65f8526 762 Gene3D G3DSA:3.40.50.970 154 413 4.4E-101 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold L21SP4_RS07000 8055a3ba308ab30875926c64c65f8526 762 Gene3D G3DSA:3.40.50.970 26 120 4.4E-101 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold L21SP4_RS07000 8055a3ba308ab30875926c64c65f8526 762 Gene3D G3DSA:3.40.50.970 441 633 4.5E-83 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold L21SP4_RS07000 8055a3ba308ab30875926c64c65f8526 762 SUPERFAMILY SSF52518 440 642 1.29E-69 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold L21SP4_RS07000 8055a3ba308ab30875926c64c65f8526 762 PANTHER PTHR11624:SF77 76 387 3.2E-179 T 22-04-2016 L21SP4_RS07000 8055a3ba308ab30875926c64c65f8526 762 PANTHER PTHR11624:SF77 430 762 3.2E-179 T 22-04-2016 L21SP4_RS10235 c87886fdb5a094bec223f477eb4fb36c 475 PANTHER PTHR11659 2 473 6.7E-239 T 22-04-2016 IPR017959 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, subunit B /E GO:0016884 L21SP4_RS10235 c87886fdb5a094bec223f477eb4fb36c 475 SMART SM00845 326 473 3.2E-74 T 22-04-2016 IPR018027 Asn/Gln amidotransferase GO:0016884 L21SP4_RS10235 c87886fdb5a094bec223f477eb4fb36c 475 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 142 156 - T 22-04-2016 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 L21SP4_RS10235 c87886fdb5a094bec223f477eb4fb36c 475 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 2 474 37.567 T 22-04-2016 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 L21SP4_RS10235 c87886fdb5a094bec223f477eb4fb36c 475 PANTHER PTHR11659:SF0 2 473 6.7E-239 T 22-04-2016 L21SP4_RS10235 c87886fdb5a094bec223f477eb4fb36c 475 Pfam PF02934 GatB/GatE catalytic domain 5 286 9.9E-110 T 22-04-2016 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 L21SP4_RS10235 c87886fdb5a094bec223f477eb4fb36c 475 Pfam PF02637 GatB domain 326 473 1.1E-51 T 22-04-2016 IPR018027 Asn/Gln amidotransferase GO:0016884 L21SP4_RS10235 c87886fdb5a094bec223f477eb4fb36c 475 SUPERFAMILY SSF55931 4 294 2.62E-113 T 22-04-2016 L21SP4_RS10235 c87886fdb5a094bec223f477eb4fb36c 475 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 1 473 1.1E-171 T 22-04-2016 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 L21SP4_RS10235 c87886fdb5a094bec223f477eb4fb36c 475 SUPERFAMILY SSF89095 295 401 1.4E-35 T 22-04-2016 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 L21SP4_RS07250 7da63603a11a6e1d361d213781f2d275 185 PRINTS PR00813 Bacterial general secretion pathway protein G signature 41 59 7.3E-6 T 22-04-2016 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 L21SP4_RS07250 7da63603a11a6e1d361d213781f2d275 185 PRINTS PR00813 Bacterial general secretion pathway protein G signature 5 30 7.3E-6 T 22-04-2016 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 L21SP4_RS07250 7da63603a11a6e1d361d213781f2d275 185 Gene3D G3DSA:3.30.700.10 6 61 5.7E-6 T 22-04-2016 L21SP4_RS07250 7da63603a11a6e1d361d213781f2d275 185 SUPERFAMILY SSF54523 6 96 3.06E-15 T 22-04-2016 L21SP4_RS07250 7da63603a11a6e1d361d213781f2d275 185 Pfam PF13633 Prokaryotic N-terminal methylation site 4 28 2.3E-8 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site L21SP4_RS07250 7da63603a11a6e1d361d213781f2d275 185 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 3 25 2.1E-7 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site L21SP4_RS07250 7da63603a11a6e1d361d213781f2d275 185 PANTHER PTHR30093 2 97 2.9E-16 T 22-04-2016 L21SP4_RS10585 edab39c2b493fc000e79eb22ed64afd8 168 PANTHER PTHR11717:SF14 10 162 4.8E-19 T 22-04-2016 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 L21SP4_RS10585 edab39c2b493fc000e79eb22ed64afd8 168 Gene3D G3DSA:3.40.50.270 7 163 6.1E-26 T 22-04-2016 L21SP4_RS10585 edab39c2b493fc000e79eb22ed64afd8 168 SUPERFAMILY SSF52788 7 159 9.42E-23 T 22-04-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily L21SP4_RS10585 edab39c2b493fc000e79eb22ed64afd8 168 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 10 158 5.2E-20 T 22-04-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily L21SP4_RS10585 edab39c2b493fc000e79eb22ed64afd8 168 PANTHER PTHR11717 10 162 4.8E-19 T 22-04-2016 L21SP4_RS10585 edab39c2b493fc000e79eb22ed64afd8 168 SMART SM00226 8 161 6.2E-13 T 22-04-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily L21SP4_RS01805 733b474577c76e05eaa5efabd4bfc2f5 325 PANTHER PTHR11732 1 320 6.8E-108 T 22-04-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta L21SP4_RS01805 733b474577c76e05eaa5efabd4bfc2f5 325 Pfam PF00248 Aldo/keto reductase family 16 317 1.4E-68 T 22-04-2016 IPR023210 NADP-dependent oxidoreductase domain L21SP4_RS01805 733b474577c76e05eaa5efabd4bfc2f5 325 SUPERFAMILY SSF51430 1 320 1.44E-88 T 22-04-2016 IPR023210 NADP-dependent oxidoreductase domain L21SP4_RS01805 733b474577c76e05eaa5efabd4bfc2f5 325 Gene3D G3DSA:3.20.20.100 1 320 8.6E-91 T 22-04-2016 IPR023210 NADP-dependent oxidoreductase domain L21SP4_RS11385 53c9a3527032b2e3647bf79b13473a22 264 PIRSF PIRSF019254 1 264 2.1E-90 T 22-04-2016 IPR007544 Encapsulating protein for peroxidase GO:0008233|GO:0042742 KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- L21SP4_RS11385 53c9a3527032b2e3647bf79b13473a22 264 PANTHER PTHR37165:SF1 1 264 8.2E-29 T 22-04-2016 L21SP4_RS11385 53c9a3527032b2e3647bf79b13473a22 264 Pfam PF04454 Encapsulating protein for peroxidase 1 251 3.5E-83 T 22-04-2016 IPR007544 Encapsulating protein for peroxidase GO:0008233|GO:0042742 KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- L21SP4_RS11385 53c9a3527032b2e3647bf79b13473a22 264 PANTHER PTHR37165 1 264 8.2E-29 T 22-04-2016 L21SP4_RS09215 3f4ae76c06c5234d0c65add570dd9d87 263 Gene3D G3DSA:2.50.20.10 38 261 1.0E-42 T 22-04-2016 L21SP4_RS09215 3f4ae76c06c5234d0c65add570dd9d87 263 Pfam PF17131 Outer membrane lipoprotein-sorting protein 86 261 2.0E-33 T 22-04-2016 IPR033399 Putative outer membrane lipoprotein-sorting protein L21SP4_RS03820 32b21ed9615b4b138f535ce9f53c54db 339 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 277 290 - T 22-04-2016 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 L21SP4_RS03820 32b21ed9615b4b138f535ce9f53c54db 339 PANTHER PTHR10584 1 328 1.6E-84 T 22-04-2016 L21SP4_RS03820 32b21ed9615b4b138f535ce9f53c54db 339 PANTHER PTHR10584:SF159 1 328 1.6E-84 T 22-04-2016 L21SP4_RS03820 32b21ed9615b4b138f535ce9f53c54db 339 Pfam PF00294 pfkB family carbohydrate kinase 32 323 5.5E-22 T 22-04-2016 IPR011611 Carbohydrate kinase PfkB L21SP4_RS03820 32b21ed9615b4b138f535ce9f53c54db 339 SUPERFAMILY SSF53613 19 335 1.09E-41 T 22-04-2016 IPR029056 Ribokinase-like L21SP4_RS03820 32b21ed9615b4b138f535ce9f53c54db 339 Gene3D G3DSA:3.40.1190.20 19 333 7.0E-53 T 22-04-2016 IPR029056 Ribokinase-like L21SP4_RS07225 363da7b20c20653675a981c68bbb8a27 385 PANTHER PTHR30146:SF24 16 315 2.4E-60 T 22-04-2016 L21SP4_RS07225 363da7b20c20653675a981c68bbb8a27 385 Pfam PF13377 Periplasmic binding protein-like domain 105 272 6.7E-37 T 22-04-2016 L21SP4_RS07225 363da7b20c20653675a981c68bbb8a27 385 SMART SM00342 296 379 1.0E-28 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP4_RS07225 363da7b20c20653675a981c68bbb8a27 385 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 333 375 - T 22-04-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 L21SP4_RS07225 363da7b20c20653675a981c68bbb8a27 385 Gene3D G3DSA:3.40.50.2300 8 105 3.3E-7 T 22-04-2016 L21SP4_RS07225 363da7b20c20653675a981c68bbb8a27 385 Gene3D G3DSA:3.40.50.2300 106 272 9.4E-35 T 22-04-2016 L21SP4_RS07225 363da7b20c20653675a981c68bbb8a27 385 PANTHER PTHR30146 16 315 2.4E-60 T 22-04-2016 L21SP4_RS07225 363da7b20c20653675a981c68bbb8a27 385 SUPERFAMILY SSF53822 4 257 5.1E-35 T 22-04-2016 IPR028082 Periplasmic binding protein-like I L21SP4_RS07225 363da7b20c20653675a981c68bbb8a27 385 SUPERFAMILY SSF46689 280 326 4.48E-5 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS07225 363da7b20c20653675a981c68bbb8a27 385 Gene3D G3DSA:1.10.10.60 279 332 7.1E-12 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS07225 363da7b20c20653675a981c68bbb8a27 385 SUPERFAMILY SSF46689 333 383 7.17E-13 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS07225 363da7b20c20653675a981c68bbb8a27 385 Pfam PF12833 Helix-turn-helix domain 303 381 1.4E-21 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP4_RS07225 363da7b20c20653675a981c68bbb8a27 385 Gene3D G3DSA:1.10.10.60 333 381 6.5E-18 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS02510 8fa6e5eec137765268e8bb587773c855 413 Pfam PF13542 Helix-turn-helix domain of transposase family ISL3 90 138 6.8E-8 T 22-04-2016 IPR032877 Transposase IS204/IS1001/IS1096/IS1165, helix-turn-helix domain L21SP4_RS02510 8fa6e5eec137765268e8bb587773c855 413 PANTHER PTHR33498:SF1 38 407 9.6E-42 T 22-04-2016 L21SP4_RS02510 8fa6e5eec137765268e8bb587773c855 413 Pfam PF01610 Transposase 155 390 5.9E-68 T 22-04-2016 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain L21SP4_RS02510 8fa6e5eec137765268e8bb587773c855 413 PANTHER PTHR33498 38 407 9.6E-42 T 22-04-2016 L21SP4_RS11710 8fa6e5eec137765268e8bb587773c855 413 Pfam PF13542 Helix-turn-helix domain of transposase family ISL3 90 138 6.8E-8 T 22-04-2016 IPR032877 Transposase IS204/IS1001/IS1096/IS1165, helix-turn-helix domain L21SP4_RS11710 8fa6e5eec137765268e8bb587773c855 413 PANTHER PTHR33498:SF1 38 407 9.6E-42 T 22-04-2016 L21SP4_RS11710 8fa6e5eec137765268e8bb587773c855 413 Pfam PF01610 Transposase 155 390 5.9E-68 T 22-04-2016 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain L21SP4_RS11710 8fa6e5eec137765268e8bb587773c855 413 PANTHER PTHR33498 38 407 9.6E-42 T 22-04-2016 L21SP4_RS06685 8fa6e5eec137765268e8bb587773c855 413 Pfam PF13542 Helix-turn-helix domain of transposase family ISL3 90 138 6.8E-8 T 22-04-2016 IPR032877 Transposase IS204/IS1001/IS1096/IS1165, helix-turn-helix domain L21SP4_RS06685 8fa6e5eec137765268e8bb587773c855 413 PANTHER PTHR33498:SF1 38 407 9.6E-42 T 22-04-2016 L21SP4_RS06685 8fa6e5eec137765268e8bb587773c855 413 Pfam PF01610 Transposase 155 390 5.9E-68 T 22-04-2016 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain L21SP4_RS06685 8fa6e5eec137765268e8bb587773c855 413 PANTHER PTHR33498 38 407 9.6E-42 T 22-04-2016 L21SP4_RS06085 55af6812d49029aa2338769f10b53a31 452 SUPERFAMILY SSF102114 12 361 3.53E-46 T 22-04-2016 L21SP4_RS06085 55af6812d49029aa2338769f10b53a31 452 Pfam PF02810 SEC-C motif 429 447 1.1E-9 T 22-04-2016 IPR004027 SEC-C motif L21SP4_RS06085 55af6812d49029aa2338769f10b53a31 452 Gene3D G3DSA:3.10.450.50 419 447 6.8E-11 T 22-04-2016 IPR032710 NTF2-like domain L21SP4_RS06085 55af6812d49029aa2338769f10b53a31 452 PANTHER PTHR11228 25 221 2.3E-127 T 22-04-2016 L21SP4_RS06085 55af6812d49029aa2338769f10b53a31 452 PANTHER PTHR11228 248 390 2.3E-127 T 22-04-2016 L21SP4_RS06085 55af6812d49029aa2338769f10b53a31 452 Pfam PF04055 Radical SAM superfamily 21 191 7.8E-16 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 L21SP4_RS06085 55af6812d49029aa2338769f10b53a31 452 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 154 429 7.0E-15 T 22-04-2016 L21SP4_RS06085 55af6812d49029aa2338769f10b53a31 452 PANTHER PTHR11228:SF24 25 221 2.3E-127 T 22-04-2016 L21SP4_RS06085 55af6812d49029aa2338769f10b53a31 452 PANTHER PTHR11228:SF24 248 390 2.3E-127 T 22-04-2016 L21SP4_RS06085 55af6812d49029aa2338769f10b53a31 452 Gene3D G3DSA:3.20.20.70 18 367 1.1E-45 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP4_RS06085 55af6812d49029aa2338769f10b53a31 452 TIGRFAM TIGR03942 sulfatase_rSAM: anaerobic sulfatase maturase 15 399 5.4E-154 T 22-04-2016 IPR023867 Anaerobic sulphatase maturase, radical SAM GO:0016491 L21SP4_RS06085 55af6812d49029aa2338769f10b53a31 452 SUPERFAMILY SSF103642 426 447 3.43E-7 T 22-04-2016 L21SP4_RS06085 55af6812d49029aa2338769f10b53a31 452 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 291 373 4.2E-18 T 22-04-2016 IPR023885 4Fe4S-binding SPASM domain L21SP4_RS06085 55af6812d49029aa2338769f10b53a31 452 Pfam PF13186 Iron-sulfur cluster-binding domain 292 352 6.4E-9 T 22-04-2016 IPR023885 4Fe4S-binding SPASM domain L21SP4_RS08690 305de64abdb713cf9bec0d7f8447b7ca 374 Pfam PF04768 NAT, N-acetyltransferase, of N-acetylglutamate synthase 207 361 9.8E-29 T 22-04-2016 IPR006855 Vertebrate-like NAGS Gcn5-related N-acetyltransferase (GNAT) domain KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068 L21SP4_RS08690 305de64abdb713cf9bec0d7f8447b7ca 374 PANTHER PTHR23342 198 359 2.3E-34 T 22-04-2016 L21SP4_RS10040 1bd47b1bac1598b50ee743136615bdef 558 Pfam PF00999 Sodium/hydrogen exchanger family 15 400 2.5E-33 T 22-04-2016 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 L21SP4_RS10040 1bd47b1bac1598b50ee743136615bdef 558 PANTHER PTHR32507 6 418 6.5E-54 T 22-04-2016 L21SP4_RS10040 1bd47b1bac1598b50ee743136615bdef 558 SUPERFAMILY SSF54631 418 525 7.99E-14 T 22-04-2016 L21SP4_RS10040 1bd47b1bac1598b50ee743136615bdef 558 PANTHER PTHR32507:SF10 6 418 6.5E-54 T 22-04-2016 L21SP4_RS10040 1bd47b1bac1598b50ee743136615bdef 558 Gene3D G3DSA:3.10.580.10 415 526 2.8E-10 T 22-04-2016 L21SP4_RS06905 6b44689cf1e0662cb439be1101045334 549 Pfam PF00118 TCP-1/cpn60 chaperonin family 23 523 5.6E-99 T 22-04-2016 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 L21SP4_RS06905 6b44689cf1e0662cb439be1101045334 549 SUPERFAMILY SSF52029 184 376 1.32E-82 T 22-04-2016 IPR027409 GroEL-like apical domain L21SP4_RS06905 6b44689cf1e0662cb439be1101045334 549 PANTHER PTHR11353 2 549 4.1E-246 T 22-04-2016 L21SP4_RS06905 6b44689cf1e0662cb439be1101045334 549 SUPERFAMILY SSF54849 138 201 1.47E-23 T 22-04-2016 L21SP4_RS06905 6b44689cf1e0662cb439be1101045334 549 TIGRFAM TIGR02348 GroEL: chaperonin GroL 3 526 2.6E-260 T 22-04-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 L21SP4_RS06905 6b44689cf1e0662cb439be1101045334 549 Gene3D G3DSA:1.10.560.10 4 188 1.9E-47 T 22-04-2016 IPR027413 GroEL-like equatorial domain L21SP4_RS06905 6b44689cf1e0662cb439be1101045334 549 Hamap MF_00600 60 kDa chaperonin [groL]. 2 545 41.989 T 22-04-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 L21SP4_RS06905 6b44689cf1e0662cb439be1101045334 549 Gene3D G3DSA:3.50.7.10 189 366 1.6E-98 T 22-04-2016 IPR027409 GroEL-like apical domain L21SP4_RS06905 6b44689cf1e0662cb439be1101045334 549 PRINTS PR00298 60kDa chaperonin signature 27 53 7.4E-75 T 22-04-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 L21SP4_RS06905 6b44689cf1e0662cb439be1101045334 549 PRINTS PR00298 60kDa chaperonin signature 268 291 7.4E-75 T 22-04-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 L21SP4_RS06905 6b44689cf1e0662cb439be1101045334 549 PRINTS PR00298 60kDa chaperonin signature 83 110 7.4E-75 T 22-04-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 L21SP4_RS06905 6b44689cf1e0662cb439be1101045334 549 PRINTS PR00298 60kDa chaperonin signature 398 419 7.4E-75 T 22-04-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 L21SP4_RS06905 6b44689cf1e0662cb439be1101045334 549 PRINTS PR00298 60kDa chaperonin signature 350 375 7.4E-75 T 22-04-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 L21SP4_RS06905 6b44689cf1e0662cb439be1101045334 549 ProSitePatterns PS00296 Chaperonins cpn60 signature. 405 416 - T 22-04-2016 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 L21SP4_RS06905 6b44689cf1e0662cb439be1101045334 549 Gene3D G3DSA:1.10.560.10 367 517 3.0E-45 T 22-04-2016 IPR027413 GroEL-like equatorial domain L21SP4_RS06905 6b44689cf1e0662cb439be1101045334 549 SUPERFAMILY SSF48592 406 520 1.83E-77 T 22-04-2016 L21SP4_RS06905 6b44689cf1e0662cb439be1101045334 549 SUPERFAMILY SSF48592 7 134 1.83E-77 T 22-04-2016 L21SP4_RS07005 1166c57b7a131ff83abdef189200c179 164 Pfam PF00364 Biotin-requiring enzyme 1 68 3.0E-17 T 22-04-2016 IPR000089 Biotin/lipoyl attachment L21SP4_RS07005 1166c57b7a131ff83abdef189200c179 164 SUPERFAMILY SSF51230 1 89 8.11E-26 T 22-04-2016 IPR011053 Single hybrid motif L21SP4_RS07005 1166c57b7a131ff83abdef189200c179 164 PANTHER PTHR23151:SF9 1 141 6.4E-31 T 22-04-2016 L21SP4_RS07005 1166c57b7a131ff83abdef189200c179 164 PANTHER PTHR23151 1 141 6.4E-31 T 22-04-2016 L21SP4_RS07005 1166c57b7a131ff83abdef189200c179 164 Gene3D G3DSA:2.40.50.100 1 89 5.0E-29 T 22-04-2016 L21SP4_RS08400 f3c8e82abb341fdc785a31b71501b4a5 212 Pfam PF00573 Ribosomal protein L4/L1 family 28 204 2.3E-56 T 22-04-2016 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 L21SP4_RS08400 f3c8e82abb341fdc785a31b71501b4a5 212 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 8 206 30.898 T 22-04-2016 IPR013005 50S ribosomal protein uL4 L21SP4_RS08400 f3c8e82abb341fdc785a31b71501b4a5 212 PANTHER PTHR10746 1 204 1.2E-61 T 22-04-2016 IPR013005 50S ribosomal protein uL4 L21SP4_RS08400 f3c8e82abb341fdc785a31b71501b4a5 212 SUPERFAMILY SSF52166 1 205 7.19E-63 T 22-04-2016 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 L21SP4_RS08400 f3c8e82abb341fdc785a31b71501b4a5 212 Gene3D G3DSA:3.40.1370.10 59 205 7.0E-47 T 22-04-2016 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 L21SP4_RS08400 f3c8e82abb341fdc785a31b71501b4a5 212 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 23 203 2.3E-60 T 22-04-2016 IPR013005 50S ribosomal protein uL4 L21SP4_RS09840 d11a730f6224bab773c0d9fd21e89287 199 SUPERFAMILY SSF47413 26 95 4.83E-8 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 L21SP4_RS09840 d11a730f6224bab773c0d9fd21e89287 199 SMART SM00530 37 93 0.0085 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 L21SP4_RS09840 d11a730f6224bab773c0d9fd21e89287 199 Gene3D G3DSA:1.10.260.40 28 97 5.6E-9 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 L21SP4_RS09840 d11a730f6224bab773c0d9fd21e89287 199 Pfam PF13744 Helix-turn-helix domain 19 94 1.7E-6 T 22-04-2016 L21SP4_RS06200 5882f7b81a2458f8d8f1930809f71861 695 TIGRFAM TIGR00484 EF-G: translation elongation factor G 1 689 0.0 T 22-04-2016 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 L21SP4_RS06200 5882f7b81a2458f8d8f1930809f71861 695 PANTHER PTHR23115:SF66 1 177 0.0 T 22-04-2016 L21SP4_RS06200 5882f7b81a2458f8d8f1930809f71861 695 PANTHER PTHR23115:SF66 299 688 0.0 T 22-04-2016 L21SP4_RS06200 5882f7b81a2458f8d8f1930809f71861 695 PANTHER PTHR23115:SF66 254 282 0.0 T 22-04-2016 L21SP4_RS06200 5882f7b81a2458f8d8f1930809f71861 695 Pfam PF00009 Elongation factor Tu GTP binding domain 9 281 1.2E-64 T 22-04-2016 L21SP4_RS06200 5882f7b81a2458f8d8f1930809f71861 695 Pfam PF00679 Elongation factor G C-terminus 596 683 3.6E-30 T 22-04-2016 IPR000640 Translation elongation factor EFG, V domain L21SP4_RS06200 5882f7b81a2458f8d8f1930809f71861 695 SMART SM00838 596 684 7.1E-50 T 22-04-2016 IPR000640 Translation elongation factor EFG, V domain L21SP4_RS06200 5882f7b81a2458f8d8f1930809f71861 695 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 179 1.9E-28 T 22-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 L21SP4_RS06200 5882f7b81a2458f8d8f1930809f71861 695 PANTHER PTHR23115 1 177 0.0 T 22-04-2016 L21SP4_RS06200 5882f7b81a2458f8d8f1930809f71861 695 PANTHER PTHR23115 299 688 0.0 T 22-04-2016 L21SP4_RS06200 5882f7b81a2458f8d8f1930809f71861 695 PANTHER PTHR23115 254 282 0.0 T 22-04-2016 L21SP4_RS06200 5882f7b81a2458f8d8f1930809f71861 695 Gene3D G3DSA:3.30.230.10 480 593 6.7E-47 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup L21SP4_RS06200 5882f7b81a2458f8d8f1930809f71861 695 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 22-04-2016 IPR031157 Tr-type G domain, conserved site L21SP4_RS06200 5882f7b81a2458f8d8f1930809f71861 695 SUPERFAMILY SSF54980 398 475 8.63E-23 T 22-04-2016 IPR009022 Elongation factor G, III-V domain L21SP4_RS06200 5882f7b81a2458f8d8f1930809f71861 695 Gene3D G3DSA:2.40.30.10 301 400 4.1E-36 T 22-04-2016 L21SP4_RS06200 5882f7b81a2458f8d8f1930809f71861 695 SUPERFAMILY SSF54980 599 688 6.23E-29 T 22-04-2016 IPR009022 Elongation factor G, III-V domain L21SP4_RS06200 5882f7b81a2458f8d8f1930809f71861 695 SUPERFAMILY SSF50447 264 400 3.77E-35 T 22-04-2016 IPR009000 Translation protein, beta-barrel domain L21SP4_RS06200 5882f7b81a2458f8d8f1930809f71861 695 Gene3D G3DSA:3.30.70.870 401 475 1.4E-32 T 22-04-2016 L21SP4_RS06200 5882f7b81a2458f8d8f1930809f71861 695 SUPERFAMILY SSF52540 6 281 6.51E-104 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS06200 5882f7b81a2458f8d8f1930809f71861 695 Hamap MF_00054_B Elongation factor G [fusA]. 6 688 101.353 T 22-04-2016 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 L21SP4_RS06200 5882f7b81a2458f8d8f1930809f71861 695 Pfam PF03764 Elongation factor G, domain IV 475 593 5.5E-44 T 22-04-2016 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 L21SP4_RS06200 5882f7b81a2458f8d8f1930809f71861 695 Pfam PF03144 Elongation factor Tu domain 2 320 387 2.2E-17 T 22-04-2016 IPR004161 Translation elongation factor EFTu/EF1A, domain 2 GO:0005525 L21SP4_RS06200 5882f7b81a2458f8d8f1930809f71861 695 SUPERFAMILY SSF54211 475 595 1.34E-42 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold L21SP4_RS06200 5882f7b81a2458f8d8f1930809f71861 695 Gene3D G3DSA:3.30.70.240 594 688 9.4E-33 T 22-04-2016 IPR000640 Translation elongation factor EFG, V domain L21SP4_RS06200 5882f7b81a2458f8d8f1930809f71861 695 Pfam PF14492 Elongation Factor G, domain II 400 473 1.6E-32 T 22-04-2016 IPR009022 Elongation factor G, III-V domain L21SP4_RS06200 5882f7b81a2458f8d8f1930809f71861 695 SMART SM00889 476 594 1.2E-62 T 22-04-2016 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 L21SP4_RS06200 5882f7b81a2458f8d8f1930809f71861 695 Gene3D G3DSA:3.40.50.300 7 285 4.2E-98 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS06200 5882f7b81a2458f8d8f1930809f71861 695 PRINTS PR00315 GTP-binding elongation factor signature 58 66 1.7E-15 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 L21SP4_RS06200 5882f7b81a2458f8d8f1930809f71861 695 PRINTS PR00315 GTP-binding elongation factor signature 130 139 1.7E-15 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 L21SP4_RS06200 5882f7b81a2458f8d8f1930809f71861 695 PRINTS PR00315 GTP-binding elongation factor signature 12 25 1.7E-15 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 L21SP4_RS06200 5882f7b81a2458f8d8f1930809f71861 695 PRINTS PR00315 GTP-binding elongation factor signature 94 105 1.7E-15 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 L21SP4_RS06200 5882f7b81a2458f8d8f1930809f71861 695 PRINTS PR00315 GTP-binding elongation factor signature 78 88 1.7E-15 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 L21SP4_RS00250 f241302164b21fdecff283a371a1ac25 153 Pfam PF13673 Acetyltransferase (GNAT) domain 27 139 6.3E-15 T 22-04-2016 IPR000182 GNAT domain GO:0008080 L21SP4_RS00250 f241302164b21fdecff283a371a1ac25 153 Gene3D G3DSA:3.40.630.30 3 152 1.4E-29 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase L21SP4_RS00250 f241302164b21fdecff283a371a1ac25 153 SUPERFAMILY SSF55729 3 152 6.35E-26 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase L21SP4_RS00250 f241302164b21fdecff283a371a1ac25 153 PANTHER PTHR23091 1 151 1.6E-16 T 22-04-2016 L21SP4_RS00515 baaf9aee347e5320db7fcbfbbba5efb2 76 Hamap MF_00088 UPF0109 protein . 1 75 22.321 T 22-04-2016 IPR020627 Uncharacterised protein family UPF0109 L21SP4_RS00515 baaf9aee347e5320db7fcbfbbba5efb2 76 Gene3D G3DSA:3.30.300.120 14 73 7.9E-9 T 22-04-2016 L21SP4_RS00515 baaf9aee347e5320db7fcbfbbba5efb2 76 SUPERFAMILY SSF54814 10 60 3.2E-6 T 22-04-2016 IPR009019 K homology domain, prokaryotic type GO:0003723 L21SP4_RS00515 baaf9aee347e5320db7fcbfbbba5efb2 76 Pfam PF13083 KH domain 2 74 2.4E-22 T 22-04-2016 L21SP4_RS00515 baaf9aee347e5320db7fcbfbbba5efb2 76 PANTHER PTHR34654 1 76 2.0E-24 T 22-04-2016 L21SP4_RS05395 da086040b4a1d69911871a103d50431d 259 PANTHER PTHR11228 82 259 6.7E-33 T 22-04-2016 L21SP4_RS05395 da086040b4a1d69911871a103d50431d 259 PANTHER PTHR11228 12 65 6.7E-33 T 22-04-2016 L21SP4_RS05395 da086040b4a1d69911871a103d50431d 259 Gene3D G3DSA:3.80.30.10 101 248 1.2E-15 T 22-04-2016 L21SP4_RS05395 da086040b4a1d69911871a103d50431d 259 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 16 259 29.9 T 22-04-2016 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703|UniPathway: UPA00391 L21SP4_RS05395 da086040b4a1d69911871a103d50431d 259 PANTHER PTHR11228:SF33 82 259 6.7E-33 T 22-04-2016 L21SP4_RS05395 da086040b4a1d69911871a103d50431d 259 PANTHER PTHR11228:SF33 12 65 6.7E-33 T 22-04-2016 L21SP4_RS05395 da086040b4a1d69911871a103d50431d 259 Pfam PF13394 4Fe-4S single cluster domain 37 143 2.0E-8 T 22-04-2016 L21SP4_RS05395 da086040b4a1d69911871a103d50431d 259 SUPERFAMILY SSF102114 41 222 1.03E-10 T 22-04-2016 L21SP4_RS05395 da086040b4a1d69911871a103d50431d 259 Pfam PF04055 Radical SAM superfamily 39 195 1.9E-14 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 L21SP4_RS05395 da086040b4a1d69911871a103d50431d 259 PIRSF PIRSF000370 14 259 2.9E-35 T 22-04-2016 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703|UniPathway: UPA00391 L21SP4_RS06365 49809c4984f75b27ac7d0e2958bf006a 591 SUPERFAMILY SSF54862 75 214 7.53E-36 T 22-04-2016 L21SP4_RS06365 49809c4984f75b27ac7d0e2958bf006a 591 Gene3D G3DSA:4.10.260.20 532 590 1.7E-25 T 22-04-2016 IPR003149 Iron hydrogenase, small subunit L21SP4_RS06365 49809c4984f75b27ac7d0e2958bf006a 591 Gene3D G3DSA:3.30.70.20 135 194 4.6E-13 T 22-04-2016 L21SP4_RS06365 49809c4984f75b27ac7d0e2958bf006a 591 PANTHER PTHR11615 3 585 1.1E-152 T 22-04-2016 L21SP4_RS06365 49809c4984f75b27ac7d0e2958bf006a 591 TIGRFAM TIGR02512 FeFe_hydrog_A: [FeFe] hydrogenase, group A 139 529 6.2E-158 T 22-04-2016 IPR013352 Iron hydrogenase, subset GO:0005506|GO:0008901|GO:0051536|GO:0055114 L21SP4_RS06365 49809c4984f75b27ac7d0e2958bf006a 591 SMART SM00902 530 589 4.9E-26 T 22-04-2016 IPR003149 Iron hydrogenase, small subunit L21SP4_RS06365 49809c4984f75b27ac7d0e2958bf006a 591 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 189 200 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site L21SP4_RS06365 49809c4984f75b27ac7d0e2958bf006a 591 SUPERFAMILY SSF54292 3 74 4.14E-19 T 22-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 L21SP4_RS06365 49809c4984f75b27ac7d0e2958bf006a 591 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 5 76 4.8E-19 T 22-04-2016 L21SP4_RS06365 49809c4984f75b27ac7d0e2958bf006a 591 SUPERFAMILY SSF53920 189 586 1.31E-127 T 22-04-2016 IPR009016 Iron hydrogenase L21SP4_RS06365 49809c4984f75b27ac7d0e2958bf006a 591 Pfam PF00037 4Fe-4S binding domain 187 205 3.3E-6 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain L21SP4_RS06365 49809c4984f75b27ac7d0e2958bf006a 591 Gene3D G3DSA:3.10.20.30 7 54 3.8E-7 T 22-04-2016 IPR012675 Beta-grasp domain L21SP4_RS06365 49809c4984f75b27ac7d0e2958bf006a 591 SMART SM00929 83 123 8.5E-16 T 22-04-2016 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 L21SP4_RS06365 49809c4984f75b27ac7d0e2958bf006a 591 Gene3D G3DSA:3.40.950.10 481 519 4.2E-10 T 22-04-2016 L21SP4_RS06365 49809c4984f75b27ac7d0e2958bf006a 591 Gene3D G3DSA:3.40.50.1780 195 247 2.9E-77 T 22-04-2016 L21SP4_RS06365 49809c4984f75b27ac7d0e2958bf006a 591 Gene3D G3DSA:3.40.50.1780 306 436 2.9E-77 T 22-04-2016 L21SP4_RS06365 49809c4984f75b27ac7d0e2958bf006a 591 PANTHER PTHR11615:SF112 3 585 1.1E-152 T 22-04-2016 L21SP4_RS06365 49809c4984f75b27ac7d0e2958bf006a 591 Pfam PF02906 Iron only hydrogenase large subunit, C-terminal domain 222 525 3.9E-96 T 22-04-2016 IPR004108 Iron hydrogenase, large subunit, C-terminal L21SP4_RS06365 49809c4984f75b27ac7d0e2958bf006a 591 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 83 120 3.8E-16 T 22-04-2016 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 L21SP4_RS06365 49809c4984f75b27ac7d0e2958bf006a 591 Pfam PF02256 Iron hydrogenase small subunit 534 588 1.1E-24 T 22-04-2016 IPR003149 Iron hydrogenase, small subunit L21SP4_RS06365 49809c4984f75b27ac7d0e2958bf006a 591 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 31 48 - T 22-04-2016 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 L21SP4_RS03895 9ecc831244c22563e548595ab1195580 824 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 269 501 8.3E-64 T 22-04-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial L21SP4_RS03895 9ecc831244c22563e548595ab1195580 824 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 640 806 1.0E-58 T 22-04-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial L21SP4_RS03895 9ecc831244c22563e548595ab1195580 824 Pfam PF07549 SecD/SecF GG Motif 562 578 3.2E-4 T 22-04-2016 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site L21SP4_RS03895 9ecc831244c22563e548595ab1195580 824 Pfam PF07549 SecD/SecF GG Motif 30 49 3.5E-5 T 22-04-2016 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site L21SP4_RS03895 9ecc831244c22563e548595ab1195580 824 PANTHER PTHR30081 210 526 2.8E-101 T 22-04-2016 L21SP4_RS03895 9ecc831244c22563e548595ab1195580 824 PANTHER PTHR30081 9 118 2.8E-101 T 22-04-2016 L21SP4_RS03895 9ecc831244c22563e548595ab1195580 824 PRINTS PR01755 Bacterial translocase SecF protein signature 677 691 1.07E-27 T 22-04-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial L21SP4_RS03895 9ecc831244c22563e548595ab1195580 824 PRINTS PR01755 Bacterial translocase SecF protein signature 559 574 1.07E-27 T 22-04-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial L21SP4_RS03895 9ecc831244c22563e548595ab1195580 824 PRINTS PR01755 Bacterial translocase SecF protein signature 757 772 1.07E-27 T 22-04-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial L21SP4_RS03895 9ecc831244c22563e548595ab1195580 824 PRINTS PR01755 Bacterial translocase SecF protein signature 725 743 1.07E-27 T 22-04-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial L21SP4_RS03895 9ecc831244c22563e548595ab1195580 824 Gene3D G3DSA:1.20.1640.10 307 516 1.1E-23 T 22-04-2016 L21SP4_RS03895 9ecc831244c22563e548595ab1195580 824 Gene3D G3DSA:1.20.1640.10 656 819 3.6E-28 T 22-04-2016 L21SP4_RS03895 9ecc831244c22563e548595ab1195580 824 Pfam PF02355 Protein export membrane protein 642 817 5.4E-69 T 22-04-2016 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial L21SP4_RS03895 9ecc831244c22563e548595ab1195580 824 Pfam PF02355 Protein export membrane protein 323 500 2.5E-12 T 22-04-2016 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial L21SP4_RS03895 9ecc831244c22563e548595ab1195580 824 SUPERFAMILY SSF82866 646 818 2.35E-38 T 22-04-2016 L21SP4_RS03895 9ecc831244c22563e548595ab1195580 824 SUPERFAMILY SSF82866 300 514 1.11E-38 T 22-04-2016 L21SP4_RS03895 9ecc831244c22563e548595ab1195580 824 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 562 809 3.6E-78 T 22-04-2016 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 L21SP4_RS03895 9ecc831244c22563e548595ab1195580 824 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 2 524 36.798 T 22-04-2016 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 L21SP4_RS03895 9ecc831244c22563e548595ab1195580 824 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 32 508 1.2E-113 T 22-04-2016 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 L21SP4_RS03895 9ecc831244c22563e548595ab1195580 824 PANTHER PTHR30081:SF1 210 526 2.8E-101 T 22-04-2016 L21SP4_RS03895 9ecc831244c22563e548595ab1195580 824 PANTHER PTHR30081:SF1 9 118 2.8E-101 T 22-04-2016 L21SP4_RS03895 9ecc831244c22563e548595ab1195580 824 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 531 820 28.45 T 22-04-2016 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 L21SP4_RS02840 eebd71acbbd401e3e32366b98c46c5db 409 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 42 119 1.2E-12 T 22-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 L21SP4_RS02840 eebd71acbbd401e3e32366b98c46c5db 409 TIGRFAM TIGR01941 nqrF: NADH:ubiquinone oxidoreductase, Na(+)-translocating, F subunit 9 409 1.7E-170 T 22-04-2016 IPR010205 Na(+)-translocating NADH-quinone reductase subunit F GO:0006814|GO:0016021|GO:0016655|GO:0051537|GO:0055114 L21SP4_RS02840 eebd71acbbd401e3e32366b98c46c5db 409 Pfam PF00970 Oxidoreductase FAD-binding domain 204 269 3.8E-8 T 22-04-2016 IPR008333 Oxidoreductase, FAD-binding domain L21SP4_RS02840 eebd71acbbd401e3e32366b98c46c5db 409 SUPERFAMILY SSF63380 109 275 3.26E-33 T 22-04-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 L21SP4_RS02840 eebd71acbbd401e3e32366b98c46c5db 409 Gene3D G3DSA:3.10.20.30 39 130 6.9E-23 T 22-04-2016 IPR012675 Beta-grasp domain L21SP4_RS02840 eebd71acbbd401e3e32366b98c46c5db 409 Gene3D G3DSA:2.40.30.10 131 267 5.8E-47 T 22-04-2016 L21SP4_RS02840 eebd71acbbd401e3e32366b98c46c5db 409 Pfam PF00175 Oxidoreductase NAD-binding domain 281 388 4.0E-12 T 22-04-2016 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 L21SP4_RS02840 eebd71acbbd401e3e32366b98c46c5db 409 SUPERFAMILY SSF54292 39 128 4.31E-23 T 22-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 L21SP4_RS02840 eebd71acbbd401e3e32366b98c46c5db 409 SUPERFAMILY SSF52343 260 406 1.7E-34 T 22-04-2016 L21SP4_RS02840 eebd71acbbd401e3e32366b98c46c5db 409 Hamap MF_00430 Na(+)-translocating NADH-quinone reductase subunit F [nqrF]. 6 409 58.992 T 22-04-2016 IPR010205 Na(+)-translocating NADH-quinone reductase subunit F GO:0006814|GO:0016021|GO:0016655|GO:0051537|GO:0055114 L21SP4_RS02840 eebd71acbbd401e3e32366b98c46c5db 409 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 279 298 8.5E-5 T 22-04-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 L21SP4_RS02840 eebd71acbbd401e3e32366b98c46c5db 409 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 165 175 8.5E-5 T 22-04-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 L21SP4_RS02840 eebd71acbbd401e3e32366b98c46c5db 409 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 245 254 8.5E-5 T 22-04-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 L21SP4_RS02840 eebd71acbbd401e3e32366b98c46c5db 409 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 213 220 8.5E-5 T 22-04-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 L21SP4_RS02840 eebd71acbbd401e3e32366b98c46c5db 409 PANTHER PTHR19370:SF32 65 180 1.1E-118 T 22-04-2016 L21SP4_RS02840 eebd71acbbd401e3e32366b98c46c5db 409 PANTHER PTHR19370:SF32 209 409 1.1E-118 T 22-04-2016 L21SP4_RS02840 eebd71acbbd401e3e32366b98c46c5db 409 PANTHER PTHR19370 65 180 1.1E-118 T 22-04-2016 L21SP4_RS02840 eebd71acbbd401e3e32366b98c46c5db 409 PANTHER PTHR19370 209 409 1.1E-118 T 22-04-2016 L21SP4_RS02840 eebd71acbbd401e3e32366b98c46c5db 409 PIRSF PIRSF000044 3 409 1.5E-174 T 22-04-2016 IPR010205 Na(+)-translocating NADH-quinone reductase subunit F GO:0006814|GO:0016021|GO:0016655|GO:0051537|GO:0055114 L21SP4_RS02840 eebd71acbbd401e3e32366b98c46c5db 409 Gene3D G3DSA:3.40.50.80 272 409 4.0E-37 T 22-04-2016 L21SP4_RS02275 52d362556e52f63c02e586dd7999c572 414 ProDom PD042532 ISOMERASE L-RHAMNOSE METAL-BINDING METABOLISM RHAMNOSE MANGANESE ENZYME KINASE 3D-STRUCTURE RHAA/RHAB 2 413 5.0E-139 T 22-04-2016 L21SP4_RS02275 52d362556e52f63c02e586dd7999c572 414 Hamap MF_00541 L-rhamnose isomerase [rhaA]. 1 414 218.405 T 22-04-2016 IPR009308 Rhamnose isomerase GO:0008740|GO:0019299|GO:0030145 KEGG: 00051+5.3.1.14|UniPathway: UPA00541 L21SP4_RS02275 52d362556e52f63c02e586dd7999c572 414 PANTHER PTHR30268 2 414 1.0E-166 T 22-04-2016 L21SP4_RS02275 52d362556e52f63c02e586dd7999c572 414 Gene3D G3DSA:3.20.20.150 2 413 8.3E-187 T 22-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain L21SP4_RS02275 52d362556e52f63c02e586dd7999c572 414 Pfam PF06134 L-rhamnose isomerase (RhaA) 2 413 6.4E-177 T 22-04-2016 IPR009308 Rhamnose isomerase GO:0008740|GO:0019299|GO:0030145 KEGG: 00051+5.3.1.14|UniPathway: UPA00541 L21SP4_RS02275 52d362556e52f63c02e586dd7999c572 414 SUPERFAMILY SSF51658 2 412 1.72E-70 T 22-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain L21SP4_RS05585 76118ac2716f6b2710a45de9b54991ba 982 SUPERFAMILY SSF52317 61 294 1.97E-37 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like L21SP4_RS05585 76118ac2716f6b2710a45de9b54991ba 982 PANTHER PTHR40469:SF1 34 372 2.3E-31 T 22-04-2016 L21SP4_RS05585 76118ac2716f6b2710a45de9b54991ba 982 Gene3D G3DSA:1.25.10.10 346 414 2.1E-6 T 22-04-2016 IPR011989 Armadillo-like helical L21SP4_RS05585 76118ac2716f6b2710a45de9b54991ba 982 Gene3D G3DSA:1.25.10.10 673 705 9.0E-12 T 22-04-2016 IPR011989 Armadillo-like helical L21SP4_RS05585 76118ac2716f6b2710a45de9b54991ba 982 Gene3D G3DSA:1.25.10.10 416 613 9.0E-12 T 22-04-2016 IPR011989 Armadillo-like helical L21SP4_RS05585 76118ac2716f6b2710a45de9b54991ba 982 Pfam PF06283 Trehalose utilisation 61 283 7.8E-41 T 22-04-2016 IPR029010 ThuA-like domain L21SP4_RS05585 76118ac2716f6b2710a45de9b54991ba 982 SUPERFAMILY SSF49785 854 967 1.93E-8 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS05585 76118ac2716f6b2710a45de9b54991ba 982 PANTHER PTHR40469 34 372 2.3E-31 T 22-04-2016 L21SP4_RS05585 76118ac2716f6b2710a45de9b54991ba 982 Gene3D G3DSA:3.40.50.880 83 294 2.9E-34 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like L21SP4_RS05585 76118ac2716f6b2710a45de9b54991ba 982 SUPERFAMILY SSF48371 425 629 2.7E-13 T 22-04-2016 IPR016024 Armadillo-type fold GO:0005488 L21SP4_RS05585 76118ac2716f6b2710a45de9b54991ba 982 Gene3D G3DSA:2.60.120.260 855 967 8.6E-8 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS05585 76118ac2716f6b2710a45de9b54991ba 982 SUPERFAMILY SSF48371 349 466 5.51E-8 T 22-04-2016 IPR016024 Armadillo-type fold GO:0005488 L21SP4_RS05585 76118ac2716f6b2710a45de9b54991ba 982 Pfam PF00754 F5/8 type C domain 855 962 1.3E-6 T 22-04-2016 IPR000421 Coagulation factor 5/8 C-terminal domain L21SP4_RS02890 c9be5cb45569d3e33622af6572d2a53a 86 SUPERFAMILY SSF53098 5 79 2.73E-12 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS02890 c9be5cb45569d3e33622af6572d2a53a 86 Gene3D G3DSA:3.30.420.10 5 78 6.1E-6 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS02890 c9be5cb45569d3e33622af6572d2a53a 86 PANTHER PTHR10948 1 82 4.5E-20 T 22-04-2016 L21SP4_RS11855 95820603aef42dba9e075958adbaf643 383 Pfam PF12833 Helix-turn-helix domain 300 379 1.9E-17 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP4_RS11855 95820603aef42dba9e075958adbaf643 383 SUPERFAMILY SSF53822 65 288 7.28E-28 T 22-04-2016 IPR028082 Periplasmic binding protein-like I L21SP4_RS11855 95820603aef42dba9e075958adbaf643 383 Gene3D G3DSA:1.10.10.60 276 331 8.0E-12 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS11855 95820603aef42dba9e075958adbaf643 383 Pfam PF13377 Periplasmic binding protein-like domain 105 270 2.3E-30 T 22-04-2016 L21SP4_RS11855 95820603aef42dba9e075958adbaf643 383 Gene3D G3DSA:3.40.50.2300 96 270 2.3E-24 T 22-04-2016 L21SP4_RS11855 95820603aef42dba9e075958adbaf643 383 SUPERFAMILY SSF46689 277 328 2.51E-7 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS11855 95820603aef42dba9e075958adbaf643 383 SMART SM00342 294 377 8.6E-19 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP4_RS11855 95820603aef42dba9e075958adbaf643 383 SUPERFAMILY SSF46689 331 381 3.27E-8 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS11855 95820603aef42dba9e075958adbaf643 383 PANTHER PTHR30146:SF24 96 313 3.1E-49 T 22-04-2016 L21SP4_RS11855 95820603aef42dba9e075958adbaf643 383 Gene3D G3DSA:1.10.10.60 333 380 4.4E-10 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS11855 95820603aef42dba9e075958adbaf643 383 PANTHER PTHR30146 96 313 3.1E-49 T 22-04-2016 L21SP4_RS05755 7e3b92a1cd92ba1897c231f06484ae60 343 PANTHER PTHR22572 96 294 6.7E-58 T 22-04-2016 L21SP4_RS05755 7e3b92a1cd92ba1897c231f06484ae60 343 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 108 141 7.2E-7 T 22-04-2016 IPR001451 Hexapeptide repeat L21SP4_RS05755 7e3b92a1cd92ba1897c231f06484ae60 343 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 145 177 1.9E-5 T 22-04-2016 IPR001451 Hexapeptide repeat L21SP4_RS05755 7e3b92a1cd92ba1897c231f06484ae60 343 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 257 291 5.5E-4 T 22-04-2016 IPR001451 Hexapeptide repeat L21SP4_RS05755 7e3b92a1cd92ba1897c231f06484ae60 343 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 222 256 6.1E-7 T 22-04-2016 IPR001451 Hexapeptide repeat L21SP4_RS05755 7e3b92a1cd92ba1897c231f06484ae60 343 Hamap MF_00523 UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase [lpxD]. 6 324 35.214 T 22-04-2016 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 UniPathway: UPA00973 L21SP4_RS05755 7e3b92a1cd92ba1897c231f06484ae60 343 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 224 252 - T 22-04-2016 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: REACT_17015 L21SP4_RS05755 7e3b92a1cd92ba1897c231f06484ae60 343 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 266 294 - T 22-04-2016 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: REACT_17015 L21SP4_RS05755 7e3b92a1cd92ba1897c231f06484ae60 343 Gene3D G3DSA:2.160.10.10 106 204 8.0E-24 T 22-04-2016 L21SP4_RS05755 7e3b92a1cd92ba1897c231f06484ae60 343 SUPERFAMILY SSF51161 30 311 1.57E-75 T 22-04-2016 IPR011004 Trimeric LpxA-like L21SP4_RS05755 7e3b92a1cd92ba1897c231f06484ae60 343 Gene3D G3DSA:2.160.10.10 205 307 1.4E-26 T 22-04-2016 L21SP4_RS05755 7e3b92a1cd92ba1897c231f06484ae60 343 Pfam PF04613 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD 20 85 1.1E-20 T 22-04-2016 IPR020573 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, non-repeat region GO:0009245|GO:0016747 UniPathway: UPA00973 L21SP4_RS05755 7e3b92a1cd92ba1897c231f06484ae60 343 TIGRFAM TIGR01853 lipid_A_lpxD: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD 5 327 5.0E-110 T 22-04-2016 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 UniPathway: UPA00973 L21SP4_RS05755 7e3b92a1cd92ba1897c231f06484ae60 343 PANTHER PTHR22572:SF117 96 294 6.7E-58 T 22-04-2016 L21SP4_RS03335 fd260593a8b0b1d23d4e744a505200bb 735 Pfam PF01555 DNA methylase 125 393 3.3E-40 T 22-04-2016 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 L21SP4_RS03335 fd260593a8b0b1d23d4e744a505200bb 735 Gene3D G3DSA:3.40.50.150 93 426 3.4E-60 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS03335 fd260593a8b0b1d23d4e744a505200bb 735 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 341 355 5.5E-20 T 22-04-2016 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 L21SP4_RS03335 fd260593a8b0b1d23d4e744a505200bb 735 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 124 136 5.5E-20 T 22-04-2016 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 L21SP4_RS03335 fd260593a8b0b1d23d4e744a505200bb 735 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 180 199 5.5E-20 T 22-04-2016 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 L21SP4_RS03335 fd260593a8b0b1d23d4e744a505200bb 735 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 318 340 5.5E-20 T 22-04-2016 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 L21SP4_RS03335 fd260593a8b0b1d23d4e744a505200bb 735 PANTHER PTHR13370:SF7 295 358 2.6E-40 T 22-04-2016 L21SP4_RS03335 fd260593a8b0b1d23d4e744a505200bb 735 PANTHER PTHR13370:SF7 379 409 2.6E-40 T 22-04-2016 L21SP4_RS03335 fd260593a8b0b1d23d4e744a505200bb 735 PANTHER PTHR13370:SF7 161 275 2.6E-40 T 22-04-2016 L21SP4_RS03335 fd260593a8b0b1d23d4e744a505200bb 735 PANTHER PTHR13370:SF7 1 133 2.6E-40 T 22-04-2016 L21SP4_RS03335 fd260593a8b0b1d23d4e744a505200bb 735 SUPERFAMILY SSF53335 88 402 1.03E-59 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS03335 fd260593a8b0b1d23d4e744a505200bb 735 PANTHER PTHR13370 295 358 2.6E-40 T 22-04-2016 L21SP4_RS03335 fd260593a8b0b1d23d4e744a505200bb 735 PANTHER PTHR13370 379 409 2.6E-40 T 22-04-2016 L21SP4_RS03335 fd260593a8b0b1d23d4e744a505200bb 735 PANTHER PTHR13370 161 275 2.6E-40 T 22-04-2016 L21SP4_RS03335 fd260593a8b0b1d23d4e744a505200bb 735 PANTHER PTHR13370 1 133 2.6E-40 T 22-04-2016 L21SP4_RS09290 35ee38ce26c9bf06a28950e33e7151a3 589 SMART SM00382 373 562 1.1E-18 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS09290 35ee38ce26c9bf06a28950e33e7151a3 589 Pfam PF00005 ABC transporter 364 513 1.1E-32 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 L21SP4_RS09290 35ee38ce26c9bf06a28950e33e7151a3 589 Gene3D G3DSA:1.20.1560.10 24 331 1.2E-70 T 22-04-2016 L21SP4_RS09290 35ee38ce26c9bf06a28950e33e7151a3 589 Pfam PF00664 ABC transporter transmembrane region 40 302 1.0E-40 T 22-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 L21SP4_RS09290 35ee38ce26c9bf06a28950e33e7151a3 589 SUPERFAMILY SSF52540 341 583 5.54E-90 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS09290 35ee38ce26c9bf06a28950e33e7151a3 589 PANTHER PTHR24221 25 588 2.2E-219 T 22-04-2016 L21SP4_RS09290 35ee38ce26c9bf06a28950e33e7151a3 589 SUPERFAMILY SSF90123 24 335 1.28E-72 T 22-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 L21SP4_RS09290 35ee38ce26c9bf06a28950e33e7151a3 589 Gene3D G3DSA:3.40.50.300 349 578 2.2E-80 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS08825 cf282b453867b454cc6ac773c93730f0 309 PANTHER PTHR10605:SF40 268 306 1.6E-18 T 22-04-2016 L21SP4_RS08825 cf282b453867b454cc6ac773c93730f0 309 PANTHER PTHR10605:SF40 9 217 1.6E-18 T 22-04-2016 L21SP4_RS08825 cf282b453867b454cc6ac773c93730f0 309 Pfam PF00685 Sulfotransferase domain 102 202 1.3E-8 T 22-04-2016 IPR000863 Sulfotransferase domain GO:0008146 L21SP4_RS08825 cf282b453867b454cc6ac773c93730f0 309 PANTHER PTHR10605 268 306 1.6E-18 T 22-04-2016 L21SP4_RS08825 cf282b453867b454cc6ac773c93730f0 309 PANTHER PTHR10605 9 217 1.6E-18 T 22-04-2016 L21SP4_RS08825 cf282b453867b454cc6ac773c93730f0 309 Gene3D G3DSA:3.40.50.300 4 303 2.0E-53 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS08825 cf282b453867b454cc6ac773c93730f0 309 SUPERFAMILY SSF52540 259 299 2.09E-46 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS08825 cf282b453867b454cc6ac773c93730f0 309 SUPERFAMILY SSF52540 7 230 2.09E-46 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS11260 d84bb246a06fc111df7602b7cfb467a7 303 Gene3D G3DSA:3.40.50.300 17 68 1.2E-15 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS11260 d84bb246a06fc111df7602b7cfb467a7 303 Gene3D G3DSA:3.40.50.300 101 240 1.2E-15 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS11260 d84bb246a06fc111df7602b7cfb467a7 303 Pfam PF13469 Sulfotransferase family 18 229 3.9E-14 T 22-04-2016 L21SP4_RS11260 d84bb246a06fc111df7602b7cfb467a7 303 SUPERFAMILY SSF52540 13 275 2.77E-29 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS03870 e68eae373f0689f7da02afac2547ed97 389 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 235 377 1.6E-64 T 22-04-2016 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 L21SP4_RS03870 e68eae373f0689f7da02afac2547ed97 389 PIRSF PIRSF000497 2 389 1.6E-158 T 22-04-2016 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 L21SP4_RS03870 e68eae373f0689f7da02afac2547ed97 389 Gene3D G3DSA:3.30.300.10 15 136 8.2E-39 T 22-04-2016 L21SP4_RS03870 e68eae373f0689f7da02afac2547ed97 389 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 8 107 7.8E-37 T 22-04-2016 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 L21SP4_RS03870 e68eae373f0689f7da02afac2547ed97 389 Pfam PF02772 S-adenosylmethionine synthetase, central domain 117 233 1.5E-37 T 22-04-2016 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 L21SP4_RS03870 e68eae373f0689f7da02afac2547ed97 389 SUPERFAMILY SSF55973 116 234 2.21E-39 T 22-04-2016 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 L21SP4_RS03870 e68eae373f0689f7da02afac2547ed97 389 SUPERFAMILY SSF55973 7 114 4.71E-39 T 22-04-2016 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 L21SP4_RS03870 e68eae373f0689f7da02afac2547ed97 389 PANTHER PTHR11964 10 386 2.5E-204 T 22-04-2016 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 L21SP4_RS03870 e68eae373f0689f7da02afac2547ed97 389 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 6 388 48.859 T 22-04-2016 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 L21SP4_RS03870 e68eae373f0689f7da02afac2547ed97 389 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 9 387 1.1E-155 T 22-04-2016 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 L21SP4_RS03870 e68eae373f0689f7da02afac2547ed97 389 Gene3D G3DSA:3.30.300.10 137 235 1.5E-29 T 22-04-2016 L21SP4_RS03870 e68eae373f0689f7da02afac2547ed97 389 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 119 129 - T 22-04-2016 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 L21SP4_RS03870 e68eae373f0689f7da02afac2547ed97 389 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 261 269 - T 22-04-2016 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 L21SP4_RS03870 e68eae373f0689f7da02afac2547ed97 389 SUPERFAMILY SSF55973 235 387 2.94E-63 T 22-04-2016 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 L21SP4_RS03870 e68eae373f0689f7da02afac2547ed97 389 Gene3D G3DSA:3.30.300.10 246 388 4.6E-65 T 22-04-2016 L21SP4_RS01940 32713733a1622860383fb8920e4d0458 462 SUPERFAMILY SSF103473 11 444 2.22E-67 T 22-04-2016 IPR020846 Major facilitator superfamily domain L21SP4_RS01940 32713733a1622860383fb8920e4d0458 462 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 13 445 4.9E-99 T 22-04-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 L21SP4_RS01940 32713733a1622860383fb8920e4d0458 462 ProSitePatterns PS00217 Sugar transport proteins signature 2. 113 138 - T 22-04-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 L21SP4_RS01940 32713733a1622860383fb8920e4d0458 462 Pfam PF00083 Sugar (and other) transporter 17 449 2.3E-96 T 22-04-2016 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 L21SP4_RS01940 32713733a1622860383fb8920e4d0458 462 Gene3D G3DSA:1.20.1250.20 21 197 1.2E-22 T 22-04-2016 L21SP4_RS01940 32713733a1622860383fb8920e4d0458 462 Gene3D G3DSA:1.20.1250.20 246 443 2.3E-17 T 22-04-2016 L21SP4_RS01940 32713733a1622860383fb8920e4d0458 462 PRINTS PR00171 Sugar transporter signature 259 269 6.1E-17 T 22-04-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 L21SP4_RS01940 32713733a1622860383fb8920e4d0458 462 PRINTS PR00171 Sugar transporter signature 368 380 6.1E-17 T 22-04-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 L21SP4_RS01940 32713733a1622860383fb8920e4d0458 462 PRINTS PR00171 Sugar transporter signature 25 35 6.1E-17 T 22-04-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 L21SP4_RS01940 32713733a1622860383fb8920e4d0458 462 PRINTS PR00171 Sugar transporter signature 108 127 6.1E-17 T 22-04-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 L21SP4_RS01940 32713733a1622860383fb8920e4d0458 462 PRINTS PR00171 Sugar transporter signature 345 366 6.1E-17 T 22-04-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 L21SP4_RS01940 32713733a1622860383fb8920e4d0458 462 PANTHER PTHR23500 13 449 7.5E-133 T 22-04-2016 L21SP4_RS02075 d7af72951ad097295f81c41ccad5c8c3 219 Gene3D G3DSA:3.40.50.10490 12 209 9.4E-47 T 22-04-2016 L21SP4_RS02075 d7af72951ad097295f81c41ccad5c8c3 219 SUPERFAMILY SSF53697 94 206 5.25E-35 T 22-04-2016 L21SP4_RS02075 d7af72951ad097295f81c41ccad5c8c3 219 SUPERFAMILY SSF53697 14 67 5.25E-35 T 22-04-2016 L21SP4_RS02075 d7af72951ad097295f81c41ccad5c8c3 219 PANTHER PTHR30390:SF6 19 66 3.8E-36 T 22-04-2016 L21SP4_RS02075 d7af72951ad097295f81c41ccad5c8c3 219 PANTHER PTHR30390:SF6 93 209 3.8E-36 T 22-04-2016 L21SP4_RS02075 d7af72951ad097295f81c41ccad5c8c3 219 Pfam PF01380 SIS domain 121 188 7.3E-8 T 22-04-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 Reactome: REACT_17015 L21SP4_RS02075 d7af72951ad097295f81c41ccad5c8c3 219 PANTHER PTHR30390 19 66 3.8E-36 T 22-04-2016 L21SP4_RS02075 d7af72951ad097295f81c41ccad5c8c3 219 PANTHER PTHR30390 93 209 3.8E-36 T 22-04-2016 L21SP4_RS01890 d4fd19080130fa440d6334a31a765e01 115 SUPERFAMILY SSF75138 2 110 5.76E-14 T 22-04-2016 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like L21SP4_RS01890 d4fd19080130fa440d6334a31a765e01 115 Gene3D G3DSA:3.40.1390.20 30 110 2.6E-9 T 22-04-2016 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like L21SP4_RS10885 109cf4e7c35404a9925b2437ce452a28 138 ProSitePatterns PS00892 HIT domain signature. 86 104 - T 22-04-2016 IPR019808 Histidine triad, conserved site L21SP4_RS10885 109cf4e7c35404a9925b2437ce452a28 138 SUPERFAMILY SSF54197 2 137 6.96E-44 T 22-04-2016 IPR011146 HIT-like domain GO:0003824 L21SP4_RS10885 109cf4e7c35404a9925b2437ce452a28 138 PANTHER PTHR23089 2 138 1.4E-45 T 22-04-2016 IPR001310 Histidine triad (HIT) protein L21SP4_RS10885 109cf4e7c35404a9925b2437ce452a28 138 Pfam PF01230 HIT domain 11 107 2.6E-26 T 22-04-2016 IPR001310 Histidine triad (HIT) protein L21SP4_RS10885 109cf4e7c35404a9925b2437ce452a28 138 Gene3D G3DSA:3.30.428.10 3 137 4.5E-43 T 22-04-2016 IPR011146 HIT-like domain GO:0003824 L21SP4_RS10885 109cf4e7c35404a9925b2437ce452a28 138 PRINTS PR00332 Histidine triad family signature 26 44 5.2E-18 T 22-04-2016 IPR001310 Histidine triad (HIT) protein L21SP4_RS10885 109cf4e7c35404a9925b2437ce452a28 138 PRINTS PR00332 Histidine triad family signature 93 103 5.2E-18 T 22-04-2016 IPR001310 Histidine triad (HIT) protein L21SP4_RS10885 109cf4e7c35404a9925b2437ce452a28 138 PRINTS PR00332 Histidine triad family signature 5 21 5.2E-18 T 22-04-2016 IPR001310 Histidine triad (HIT) protein L21SP4_RS10885 109cf4e7c35404a9925b2437ce452a28 138 PANTHER PTHR23089:SF7 2 138 1.4E-45 T 22-04-2016 L21SP4_RS06740 1077315207cc190150cd8171edd86d1e 65 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 16.163 T 22-04-2016 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 L21SP4_RS06740 1077315207cc190150cd8171edd86d1e 65 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 22-04-2016 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS06740 1077315207cc190150cd8171edd86d1e 65 SUPERFAMILY SSF143034 2 64 5.1E-20 T 22-04-2016 L21SP4_RS06740 1077315207cc190150cd8171edd86d1e 65 PANTHER PTHR33343 1 64 1.3E-20 T 22-04-2016 L21SP4_RS06740 1077315207cc190150cd8171edd86d1e 65 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 64 8.4E-21 T 22-04-2016 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 L21SP4_RS06740 1077315207cc190150cd8171edd86d1e 65 Pfam PF01632 Ribosomal protein L35 2 60 3.7E-20 T 22-04-2016 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS06740 1077315207cc190150cd8171edd86d1e 65 PRINTS PR00064 Ribosomal protein L35 signature 21 35 5.9E-15 T 22-04-2016 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 L21SP4_RS06740 1077315207cc190150cd8171edd86d1e 65 PRINTS PR00064 Ribosomal protein L35 signature 36 54 5.9E-15 T 22-04-2016 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 L21SP4_RS06740 1077315207cc190150cd8171edd86d1e 65 PRINTS PR00064 Ribosomal protein L35 signature 3 20 5.9E-15 T 22-04-2016 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 L21SP4_RS01620 674555fb7988c3768b70d78fdf738b9d 208 SUPERFAMILY SSF52242 69 206 1.57E-36 T 22-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 L21SP4_RS01620 674555fb7988c3768b70d78fdf738b9d 208 SMART SM01018 1 84 2.4E-21 T 22-04-2016 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain L21SP4_RS01620 674555fb7988c3768b70d78fdf738b9d 208 Gene3D G3DSA:1.10.1240.10 3 74 2.0E-18 T 22-04-2016 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain L21SP4_RS01620 674555fb7988c3768b70d78fdf738b9d 208 Pfam PF02607 B12 binding domain 5 76 5.1E-19 T 22-04-2016 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain L21SP4_RS01620 674555fb7988c3768b70d78fdf738b9d 208 SUPERFAMILY SSF47644 3 82 1.7E-20 T 22-04-2016 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain L21SP4_RS01620 674555fb7988c3768b70d78fdf738b9d 208 Gene3D G3DSA:3.40.50.280 75 205 9.6E-40 T 22-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 L21SP4_RS01620 674555fb7988c3768b70d78fdf738b9d 208 Pfam PF02310 B12 binding domain 90 195 2.2E-21 T 22-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 L21SP4_RS05390 14ab25dc755ec00b9585586a21acc197 235 PANTHER PTHR11587 5 233 1.8E-105 T 22-04-2016 L21SP4_RS05390 14ab25dc755ec00b9585586a21acc197 235 Gene3D G3DSA:3.40.50.620 5 234 1.2E-78 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP4_RS05390 14ab25dc755ec00b9585586a21acc197 235 PANTHER PTHR11587:SF3 5 233 1.8E-105 T 22-04-2016 L21SP4_RS05390 14ab25dc755ec00b9585586a21acc197 235 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 6 230 54.339 T 22-04-2016 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703|UniPathway: UPA00391 L21SP4_RS05390 14ab25dc755ec00b9585586a21acc197 235 Pfam PF06508 Queuosine biosynthesis protein QueC 7 224 3.0E-74 T 22-04-2016 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703|UniPathway: UPA00391 L21SP4_RS05390 14ab25dc755ec00b9585586a21acc197 235 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 8 217 5.4E-58 T 22-04-2016 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703|UniPathway: UPA00391 L21SP4_RS05390 14ab25dc755ec00b9585586a21acc197 235 PIRSF PIRSF006293 4 235 6.0E-77 T 22-04-2016 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703|UniPathway: UPA00391 L21SP4_RS05390 14ab25dc755ec00b9585586a21acc197 235 SUPERFAMILY SSF52402 6 233 4.85E-63 T 22-04-2016 L21SP4_RS04265 30d404234767a5a18b35574457194472 294 Pfam PF00781 Diacylglycerol kinase catalytic domain 3 123 3.0E-27 T 22-04-2016 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 L21SP4_RS04265 30d404234767a5a18b35574457194472 294 SUPERFAMILY SSF111331 1 292 2.62E-66 T 22-04-2016 IPR016064 NAD kinase/diacylglycerol kinase-like domain L21SP4_RS04265 30d404234767a5a18b35574457194472 294 SMART SM00046 3 127 1.3E-4 T 22-04-2016 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 L21SP4_RS04265 30d404234767a5a18b35574457194472 294 PANTHER PTHR12358 3 294 1.8E-47 T 22-04-2016 L21SP4_RS07885 21a5801fc29e0db0213b3c24572957d5 119 SUPERFAMILY SSF47979 66 118 1.7E-12 T 22-04-2016 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 L21SP4_RS07885 21a5801fc29e0db0213b3c24572957d5 119 PANTHER PTHR33238:SF1 3 119 5.3E-31 T 22-04-2016 L21SP4_RS07885 21a5801fc29e0db0213b3c24572957d5 119 SMART SM00529 27 119 5.0E-22 T 22-04-2016 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 L21SP4_RS07885 21a5801fc29e0db0213b3c24572957d5 119 SUPERFAMILY SSF46785 6 65 9.12E-16 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS07885 21a5801fc29e0db0213b3c24572957d5 119 Gene3D G3DSA:1.10.10.10 5 76 8.6E-26 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS07885 21a5801fc29e0db0213b3c24572957d5 119 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 5 61 1.8E-16 T 22-04-2016 IPR022687 DTXR-type HTH domain GO:0003677 L21SP4_RS07885 21a5801fc29e0db0213b3c24572957d5 119 PANTHER PTHR33238 3 119 5.3E-31 T 22-04-2016 L21SP4_RS07885 21a5801fc29e0db0213b3c24572957d5 119 Gene3D G3DSA:1.10.60.10 77 117 6.6E-10 T 22-04-2016 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 L21SP4_RS07885 21a5801fc29e0db0213b3c24572957d5 119 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 66 118 5.3E-14 T 22-04-2016 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 L21SP4_RS06410 363a42fcf18d69f0890b07ff78b78e59 234 Pfam PF04055 Radical SAM superfamily 27 172 6.4E-17 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 L21SP4_RS06410 363a42fcf18d69f0890b07ff78b78e59 234 PANTHER PTHR11228 14 230 1.2E-36 T 22-04-2016 L21SP4_RS06410 363a42fcf18d69f0890b07ff78b78e59 234 SUPERFAMILY SSF102114 17 223 4.71E-26 T 22-04-2016 L21SP4_RS06410 363a42fcf18d69f0890b07ff78b78e59 234 TIGRFAM TIGR02495 NrdG2: anaerobic ribonucleoside-triphosphate reductase activating protein 14 191 6.2E-44 T 22-04-2016 IPR012840 Anaerobic ribonucleoside-triphosphate reductase activating protein L21SP4_RS06410 363a42fcf18d69f0890b07ff78b78e59 234 Pfam PF13353 4Fe-4S single cluster domain 19 108 4.2E-9 T 22-04-2016 L21SP4_RS06410 363a42fcf18d69f0890b07ff78b78e59 234 PANTHER PTHR11228:SF27 14 230 1.2E-36 T 22-04-2016 L21SP4_RS06410 363a42fcf18d69f0890b07ff78b78e59 234 Gene3D G3DSA:3.20.20.70 19 230 7.7E-28 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP4_RS02240 c0465b8368d91b7dff790657130ef689 138 TIGRFAM TIGR00305 TIGR00305: putative toxin-antitoxin system toxin component, PIN family 2 108 6.7E-12 T 22-04-2016 IPR002850 PIN family, putative toxin-antitoxin system toxin component L21SP4_RS02240 c0465b8368d91b7dff790657130ef689 138 Pfam PF13470 PIN domain 2 111 1.8E-16 T 22-04-2016 IPR002716 PIN domain L21SP4_RS02240 c0465b8368d91b7dff790657130ef689 138 PANTHER PTHR34610 1 138 2.7E-24 T 22-04-2016 L21SP4_RS02240 c0465b8368d91b7dff790657130ef689 138 Gene3D G3DSA:3.40.50.1010 88 134 4.1E-4 T 22-04-2016 IPR029060 PIN domain-like L21SP4_RS02240 c0465b8368d91b7dff790657130ef689 138 SUPERFAMILY SSF88723 1 115 9.81E-14 T 22-04-2016 IPR029060 PIN domain-like L21SP4_RS02240 c0465b8368d91b7dff790657130ef689 138 PANTHER PTHR34610:SF3 1 138 2.7E-24 T 22-04-2016 L21SP4_RS03125 5d45ef7c25428e5395b94e1b5207799e 421 Pfam PF13641 Glycosyltransferase like family 2 53 277 5.4E-19 T 22-04-2016 L21SP4_RS03125 5d45ef7c25428e5395b94e1b5207799e 421 SUPERFAMILY SSF53448 54 291 5.53E-32 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases L21SP4_RS03125 5d45ef7c25428e5395b94e1b5207799e 421 PANTHER PTHR10859:SF96 32 401 2.7E-50 T 22-04-2016 L21SP4_RS03125 5d45ef7c25428e5395b94e1b5207799e 421 Gene3D G3DSA:3.90.550.10 55 298 4.9E-15 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases L21SP4_RS03125 5d45ef7c25428e5395b94e1b5207799e 421 PANTHER PTHR10859 32 401 2.7E-50 T 22-04-2016 L21SP4_RS02605 68e62364a36def519db552130a629034 458 SUPERFAMILY SSF55957 361 456 2.35E-16 T 22-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP4_RS02605 68e62364a36def519db552130a629034 458 SUPERFAMILY SSF53738 267 369 2.51E-22 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP4_RS02605 68e62364a36def519db552130a629034 458 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 98 107 - T 22-04-2016 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP4_RS02605 68e62364a36def519db552130a629034 458 SUPERFAMILY SSF53738 11 144 3.37E-37 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP4_RS02605 68e62364a36def519db552130a629034 458 PANTHER PTHR22573 7 450 3.7E-107 T 22-04-2016 L21SP4_RS02605 68e62364a36def519db552130a629034 458 Gene3D G3DSA:3.40.120.10 258 373 2.7E-22 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP4_RS02605 68e62364a36def519db552130a629034 458 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 12 138 1.3E-33 T 22-04-2016 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP4_RS02605 68e62364a36def519db552130a629034 458 SUPERFAMILY SSF53738 161 260 2.55E-23 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP4_RS02605 68e62364a36def519db552130a629034 458 Gene3D G3DSA:3.40.120.10 179 257 2.5E-22 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP4_RS02605 68e62364a36def519db552130a629034 458 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 97 111 1.1E-10 T 22-04-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP4_RS02605 68e62364a36def519db552130a629034 458 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 239 254 1.1E-10 T 22-04-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP4_RS02605 68e62364a36def519db552130a629034 458 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 178 197 1.1E-10 T 22-04-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP4_RS02605 68e62364a36def519db552130a629034 458 TIGRFAM TIGR03990 Arch_GlmM: phosphoglucosamine mutase 13 450 2.6E-141 T 22-04-2016 IPR024086 Phosphoglucosamine mutase, archaeal type GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP4_RS02605 68e62364a36def519db552130a629034 458 Gene3D G3DSA:3.40.120.10 11 153 8.2E-34 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP4_RS02605 68e62364a36def519db552130a629034 458 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 160 259 1.5E-25 T 22-04-2016 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP4_RS02605 68e62364a36def519db552130a629034 458 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 390 450 2.4E-9 T 22-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP4_RS02605 68e62364a36def519db552130a629034 458 Gene3D G3DSA:3.30.310.50 374 453 2.3E-15 T 22-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP4_RS02605 68e62364a36def519db552130a629034 458 PANTHER PTHR22573:SF48 7 450 3.7E-107 T 22-04-2016 L21SP4_RS02605 68e62364a36def519db552130a629034 458 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 269 371 5.3E-20 T 22-04-2016 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP4_RS05790 1eb4a22fbad2338c7897830620e2b6a5 103 Pfam PF01250 Ribosomal protein S6 4 92 2.7E-18 T 22-04-2016 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 L21SP4_RS05790 1eb4a22fbad2338c7897830620e2b6a5 103 SUPERFAMILY SSF54995 2 96 9.03E-21 T 22-04-2016 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 L21SP4_RS05790 1eb4a22fbad2338c7897830620e2b6a5 103 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 90 4.8E-15 T 22-04-2016 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 L21SP4_RS05790 1eb4a22fbad2338c7897830620e2b6a5 103 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 95 14.852 T 22-04-2016 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 L21SP4_RS05790 1eb4a22fbad2338c7897830620e2b6a5 103 Gene3D G3DSA:3.30.70.60 2 97 2.0E-20 T 22-04-2016 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 L21SP4_RS01765 b0d529f340e5de8d8c15cb00993c8eb4 490 SUPERFAMILY SSF53649 32 478 5.52E-112 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS01765 b0d529f340e5de8d8c15cb00993c8eb4 490 Pfam PF00884 Sulfatase 32 372 5.7E-68 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS01765 b0d529f340e5de8d8c15cb00993c8eb4 490 PANTHER PTHR10342 3 479 3.1E-129 T 22-04-2016 L21SP4_RS01765 b0d529f340e5de8d8c15cb00993c8eb4 490 PANTHER PTHR10342:SF199 3 479 3.1E-129 T 22-04-2016 L21SP4_RS01765 b0d529f340e5de8d8c15cb00993c8eb4 490 Gene3D G3DSA:3.40.720.10 31 387 2.5E-102 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS01765 b0d529f340e5de8d8c15cb00993c8eb4 490 ProSitePatterns PS00523 Sulfatases signature 1. 78 90 - T 22-04-2016 IPR024607 Sulfatase, conserved site L21SP4_RS01765 b0d529f340e5de8d8c15cb00993c8eb4 490 Gene3D G3DSA:3.30.1120.10 388 478 4.5E-7 T 22-04-2016 L21SP4_RS01765 b0d529f340e5de8d8c15cb00993c8eb4 490 ProSitePatterns PS00149 Sulfatases signature 2. 125 135 - T 22-04-2016 IPR024607 Sulfatase, conserved site L21SP4_RS08530 18b69d3b8886ea7d6f5a06dc12a80402 257 Gene3D G3DSA:2.10.110.10 198 246 9.8E-4 T 22-04-2016 IPR001781 Zinc finger, LIM-type GO:0008270 L21SP4_RS08530 18b69d3b8886ea7d6f5a06dc12a80402 257 Pfam PF14451 Mut7-C ubiquitin 16 94 1.1E-29 T 22-04-2016 IPR027798 Ubiquitin Mut7-C domain L21SP4_RS08530 18b69d3b8886ea7d6f5a06dc12a80402 257 PANTHER PTHR12124 61 254 6.3E-29 T 22-04-2016 L21SP4_RS08530 18b69d3b8886ea7d6f5a06dc12a80402 257 Pfam PF01927 Mut7-C RNAse domain 109 252 1.6E-47 T 22-04-2016 IPR002782 Mut7-C RNAse domain L21SP4_RS08530 18b69d3b8886ea7d6f5a06dc12a80402 257 Gene3D G3DSA:3.10.20.30 48 90 1.3E-5 T 22-04-2016 IPR012675 Beta-grasp domain L21SP4_RS08530 18b69d3b8886ea7d6f5a06dc12a80402 257 PANTHER PTHR12124:SF44 61 254 6.3E-29 T 22-04-2016 L21SP4_RS05045 17eb54ce2bcdd74f7367ac754eb50e5b 266 Pfam PF00069 Protein kinase domain 51 257 4.7E-34 T 22-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 L21SP4_RS05045 17eb54ce2bcdd74f7367ac754eb50e5b 266 PANTHER PTHR24362 5 264 6.8E-57 T 22-04-2016 L21SP4_RS05045 17eb54ce2bcdd74f7367ac754eb50e5b 266 PANTHER PTHR24362:SF160 5 264 6.8E-57 T 22-04-2016 L21SP4_RS05045 17eb54ce2bcdd74f7367ac754eb50e5b 266 PIRSF PIRSF000654 2 266 3.9E-24 T 22-04-2016 L21SP4_RS05045 17eb54ce2bcdd74f7367ac754eb50e5b 266 Gene3D G3DSA:1.10.510.10 73 259 3.0E-42 T 22-04-2016 L21SP4_RS05045 17eb54ce2bcdd74f7367ac754eb50e5b 266 SUPERFAMILY SSF56112 4 262 2.16E-56 T 22-04-2016 IPR011009 Protein kinase-like domain L21SP4_RS05045 17eb54ce2bcdd74f7367ac754eb50e5b 266 Gene3D G3DSA:3.30.200.20 5 72 8.0E-9 T 22-04-2016 L21SP4_RS10170 df25030e4469f3d6e7d7bc4a36e22a65 189 Pfam PF01066 CDP-alcohol phosphatidyltransferase 6 69 1.1E-7 T 22-04-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 L21SP4_RS10170 df25030e4469f3d6e7d7bc4a36e22a65 189 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 47 69 - T 22-04-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 L21SP4_RS05025 bd06a0f01dc02b18c80c5b587fc1ad84 424 PANTHER PTHR11476 5 424 4.6E-145 T 22-04-2016 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 Reactome: REACT_71 L21SP4_RS05025 bd06a0f01dc02b18c80c5b587fc1ad84 424 PANTHER PTHR11476:SF9 5 424 4.6E-145 T 22-04-2016 L21SP4_RS05025 bd06a0f01dc02b18c80c5b587fc1ad84 424 SUPERFAMILY SSF55681 6 312 1.53E-77 T 22-04-2016 L21SP4_RS05025 bd06a0f01dc02b18c80c5b587fc1ad84 424 PIRSF PIRSF001549 4 418 1.2E-100 T 22-04-2016 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 Reactome: REACT_71 L21SP4_RS05025 bd06a0f01dc02b18c80c5b587fc1ad84 424 Pfam PF03129 Anticodon binding domain 330 412 5.7E-10 T 22-04-2016 IPR004154 Anticodon-binding L21SP4_RS05025 bd06a0f01dc02b18c80c5b587fc1ad84 424 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 7 406 2.2E-125 T 22-04-2016 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21|Reactome: REACT_71 L21SP4_RS05025 bd06a0f01dc02b18c80c5b587fc1ad84 424 Gene3D G3DSA:3.30.930.10 6 184 1.0E-75 T 22-04-2016 L21SP4_RS05025 bd06a0f01dc02b18c80c5b587fc1ad84 424 Gene3D G3DSA:3.30.930.10 220 317 1.0E-75 T 22-04-2016 L21SP4_RS05025 bd06a0f01dc02b18c80c5b587fc1ad84 424 SUPERFAMILY SSF52954 328 412 1.06E-18 T 22-04-2016 IPR004154 Anticodon-binding L21SP4_RS05025 bd06a0f01dc02b18c80c5b587fc1ad84 424 Gene3D G3DSA:3.40.50.800 328 410 1.3E-22 T 22-04-2016 IPR004154 Anticodon-binding L21SP4_RS05025 bd06a0f01dc02b18c80c5b587fc1ad84 424 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 4 418 27.346 T 22-04-2016 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21|Reactome: REACT_71 L21SP4_RS05025 bd06a0f01dc02b18c80c5b587fc1ad84 424 Pfam PF13393 Histidyl-tRNA synthetase 11 308 6.6E-39 T 22-04-2016 L21SP4_RS01165 d6890f22ab34b95dfe2f54644b54648b 340 PANTHER PTHR34069 13 337 2.6E-120 T 22-04-2016 L21SP4_RS01165 d6890f22ab34b95dfe2f54644b54648b 340 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 250 337 1.2E-29 T 22-04-2016 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 L21SP4_RS01165 d6890f22ab34b95dfe2f54644b54648b 340 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 15 338 65.369 T 22-04-2016 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 L21SP4_RS01165 d6890f22ab34b95dfe2f54644b54648b 340 Gene3D G3DSA:3.40.47.10 174 337 2.9E-46 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 L21SP4_RS01165 d6890f22ab34b95dfe2f54644b54648b 340 SUPERFAMILY SSF53901 16 337 1.73E-69 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 L21SP4_RS01165 d6890f22ab34b95dfe2f54644b54648b 340 PANTHER PTHR34069:SF2 13 337 2.6E-120 T 22-04-2016 L21SP4_RS01165 d6890f22ab34b95dfe2f54644b54648b 340 Gene3D G3DSA:3.40.47.10 15 173 5.8E-66 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 L21SP4_RS01165 d6890f22ab34b95dfe2f54644b54648b 340 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 120 198 8.2E-29 T 22-04-2016 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 L21SP4_RS01165 d6890f22ab34b95dfe2f54644b54648b 340 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 16 337 1.8E-119 T 22-04-2016 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 L21SP4_RS07230 11fb3700bf420ba12cb80f5231ae90ed 443 Pfam PF08388 Group II intron, maturase-specific domain 354 421 2.8E-14 T 22-04-2016 IPR013597 Group II intron, maturase-specific L21SP4_RS07230 11fb3700bf420ba12cb80f5231ae90ed 443 PANTHER PTHR19446 67 365 2.6E-64 T 22-04-2016 L21SP4_RS07230 11fb3700bf420ba12cb80f5231ae90ed 443 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 50 418 1.6E-109 T 22-04-2016 IPR030931 Group II intron reverse transcriptase/maturase L21SP4_RS07230 11fb3700bf420ba12cb80f5231ae90ed 443 PANTHER PTHR19446:SF383 67 365 2.6E-64 T 22-04-2016 L21SP4_RS07230 11fb3700bf420ba12cb80f5231ae90ed 443 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 109 329 5.9E-35 T 22-04-2016 IPR000477 Reverse transcriptase domain L21SP4_RS07230 11fb3700bf420ba12cb80f5231ae90ed 443 SUPERFAMILY SSF56672 56 344 6.35E-46 T 22-04-2016 L21SP4_RS00370 11fb3700bf420ba12cb80f5231ae90ed 443 Pfam PF08388 Group II intron, maturase-specific domain 354 421 2.8E-14 T 22-04-2016 IPR013597 Group II intron, maturase-specific L21SP4_RS00370 11fb3700bf420ba12cb80f5231ae90ed 443 PANTHER PTHR19446 67 365 2.6E-64 T 22-04-2016 L21SP4_RS00370 11fb3700bf420ba12cb80f5231ae90ed 443 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 50 418 1.6E-109 T 22-04-2016 IPR030931 Group II intron reverse transcriptase/maturase L21SP4_RS00370 11fb3700bf420ba12cb80f5231ae90ed 443 PANTHER PTHR19446:SF383 67 365 2.6E-64 T 22-04-2016 L21SP4_RS00370 11fb3700bf420ba12cb80f5231ae90ed 443 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 109 329 5.9E-35 T 22-04-2016 IPR000477 Reverse transcriptase domain L21SP4_RS00370 11fb3700bf420ba12cb80f5231ae90ed 443 SUPERFAMILY SSF56672 56 344 6.35E-46 T 22-04-2016 L21SP4_RS01260 11fb3700bf420ba12cb80f5231ae90ed 443 Pfam PF08388 Group II intron, maturase-specific domain 354 421 2.8E-14 T 22-04-2016 IPR013597 Group II intron, maturase-specific L21SP4_RS01260 11fb3700bf420ba12cb80f5231ae90ed 443 PANTHER PTHR19446 67 365 2.6E-64 T 22-04-2016 L21SP4_RS01260 11fb3700bf420ba12cb80f5231ae90ed 443 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 50 418 1.6E-109 T 22-04-2016 IPR030931 Group II intron reverse transcriptase/maturase L21SP4_RS01260 11fb3700bf420ba12cb80f5231ae90ed 443 PANTHER PTHR19446:SF383 67 365 2.6E-64 T 22-04-2016 L21SP4_RS01260 11fb3700bf420ba12cb80f5231ae90ed 443 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 109 329 5.9E-35 T 22-04-2016 IPR000477 Reverse transcriptase domain L21SP4_RS01260 11fb3700bf420ba12cb80f5231ae90ed 443 SUPERFAMILY SSF56672 56 344 6.35E-46 T 22-04-2016 L21SP4_RS05260 11fb3700bf420ba12cb80f5231ae90ed 443 Pfam PF08388 Group II intron, maturase-specific domain 354 421 2.8E-14 T 22-04-2016 IPR013597 Group II intron, maturase-specific L21SP4_RS05260 11fb3700bf420ba12cb80f5231ae90ed 443 PANTHER PTHR19446 67 365 2.6E-64 T 22-04-2016 L21SP4_RS05260 11fb3700bf420ba12cb80f5231ae90ed 443 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 50 418 1.6E-109 T 22-04-2016 IPR030931 Group II intron reverse transcriptase/maturase L21SP4_RS05260 11fb3700bf420ba12cb80f5231ae90ed 443 PANTHER PTHR19446:SF383 67 365 2.6E-64 T 22-04-2016 L21SP4_RS05260 11fb3700bf420ba12cb80f5231ae90ed 443 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 109 329 5.9E-35 T 22-04-2016 IPR000477 Reverse transcriptase domain L21SP4_RS05260 11fb3700bf420ba12cb80f5231ae90ed 443 SUPERFAMILY SSF56672 56 344 6.35E-46 T 22-04-2016 L21SP4_RS11320 11fb3700bf420ba12cb80f5231ae90ed 443 Pfam PF08388 Group II intron, maturase-specific domain 354 421 2.8E-14 T 22-04-2016 IPR013597 Group II intron, maturase-specific L21SP4_RS11320 11fb3700bf420ba12cb80f5231ae90ed 443 PANTHER PTHR19446 67 365 2.6E-64 T 22-04-2016 L21SP4_RS11320 11fb3700bf420ba12cb80f5231ae90ed 443 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 50 418 1.6E-109 T 22-04-2016 IPR030931 Group II intron reverse transcriptase/maturase L21SP4_RS11320 11fb3700bf420ba12cb80f5231ae90ed 443 PANTHER PTHR19446:SF383 67 365 2.6E-64 T 22-04-2016 L21SP4_RS11320 11fb3700bf420ba12cb80f5231ae90ed 443 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 109 329 5.9E-35 T 22-04-2016 IPR000477 Reverse transcriptase domain L21SP4_RS11320 11fb3700bf420ba12cb80f5231ae90ed 443 SUPERFAMILY SSF56672 56 344 6.35E-46 T 22-04-2016 L21SP4_RS10715 721e52e7404d636ddde961e9d983d153 312 Gene3D G3DSA:3.40.50.720 2 164 1.6E-43 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS10715 721e52e7404d636ddde961e9d983d153 312 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 1 303 30.777 T 22-04-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 L21SP4_RS10715 721e52e7404d636ddde961e9d983d153 312 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 39 66 4.3E-36 T 22-04-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 L21SP4_RS10715 721e52e7404d636ddde961e9d983d153 312 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 179 203 4.3E-36 T 22-04-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 L21SP4_RS10715 721e52e7404d636ddde961e9d983d153 312 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 114 134 4.3E-36 T 22-04-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 L21SP4_RS10715 721e52e7404d636ddde961e9d983d153 312 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 219 236 4.3E-36 T 22-04-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 L21SP4_RS10715 721e52e7404d636ddde961e9d983d153 312 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 154 178 4.3E-36 T 22-04-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 L21SP4_RS10715 721e52e7404d636ddde961e9d983d153 312 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2 140 2.4E-31 T 22-04-2016 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 L21SP4_RS10715 721e52e7404d636ddde961e9d983d153 312 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 169 190 - T 22-04-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 L21SP4_RS10715 721e52e7404d636ddde961e9d983d153 312 SUPERFAMILY SSF51735 2 159 8.19E-36 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS10715 721e52e7404d636ddde961e9d983d153 312 PANTHER PTHR11728 1 312 2.2E-109 T 22-04-2016 L21SP4_RS10715 721e52e7404d636ddde961e9d983d153 312 SUPERFAMILY SSF48179 160 312 3.91E-52 T 22-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 L21SP4_RS10715 721e52e7404d636ddde961e9d983d153 312 Gene3D G3DSA:1.10.1040.10 165 307 1.4E-54 T 22-04-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 L21SP4_RS10715 721e52e7404d636ddde961e9d983d153 312 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 161 301 2.4E-50 T 22-04-2016 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 L21SP4_RS10715 721e52e7404d636ddde961e9d983d153 312 PIRSF PIRSF000114 1 312 8.5E-81 T 22-04-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 L21SP4_RS05000 a927ada274237b1993138a0db2c7796d 440 PANTHER PTHR21090 5 437 1.0E-158 T 22-04-2016 L21SP4_RS05000 a927ada274237b1993138a0db2c7796d 440 Gene3D G3DSA:3.65.10.10 234 430 2.6E-54 T 22-04-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 L21SP4_RS05000 a927ada274237b1993138a0db2c7796d 440 PANTHER PTHR21090:SF5 5 437 1.0E-158 T 22-04-2016 L21SP4_RS05000 a927ada274237b1993138a0db2c7796d 440 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 13 430 3.2E-119 T 22-04-2016 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163|UniPathway: UPA00053 L21SP4_RS05000 a927ada274237b1993138a0db2c7796d 440 ProSitePatterns PS00104 EPSP synthase signature 1. 86 100 - T 22-04-2016 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163|UniPathway: UPA00053 L21SP4_RS05000 a927ada274237b1993138a0db2c7796d 440 ProSitePatterns PS00885 EPSP synthase signature 2. 341 359 - T 22-04-2016 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163|UniPathway: UPA00053 L21SP4_RS05000 a927ada274237b1993138a0db2c7796d 440 PIRSF PIRSF000505 1 435 2.7E-118 T 22-04-2016 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163|UniPathway: UPA00053 L21SP4_RS05000 a927ada274237b1993138a0db2c7796d 440 SUPERFAMILY SSF55205 8 430 1.8E-121 T 22-04-2016 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 L21SP4_RS05000 a927ada274237b1993138a0db2c7796d 440 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 9 432 32.449 T 22-04-2016 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163|UniPathway: UPA00053 L21SP4_RS05000 a927ada274237b1993138a0db2c7796d 440 Gene3D G3DSA:3.65.10.10 21 233 2.1E-56 T 22-04-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 L21SP4_RS05000 a927ada274237b1993138a0db2c7796d 440 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 425 1.3E-110 T 22-04-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 L21SP4_RS00860 5d96fb420976f8de44b71b35ba36f580 171 Pfam PF03994 Domain of Unknown Function (DUF350) 100 149 4.0E-6 T 22-04-2016 IPR007140 Protein of unknown function DUF350 L21SP4_RS05785 7599bf1778a243d141a975b80545d568 144 PANTHER PTHR10302 4 140 3.1E-38 T 22-04-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 L21SP4_RS05785 7599bf1778a243d141a975b80545d568 144 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 2 138 3.6E-42 T 22-04-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 L21SP4_RS05785 7599bf1778a243d141a975b80545d568 144 Hamap MF_00984 Single-stranded DNA-binding protein. 4 111 31.761 T 22-04-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 L21SP4_RS05785 7599bf1778a243d141a975b80545d568 144 PANTHER PTHR10302:SF0 4 140 3.1E-38 T 22-04-2016 L21SP4_RS05785 7599bf1778a243d141a975b80545d568 144 Pfam PF00436 Single-strand binding protein family 4 107 1.7E-35 T 22-04-2016 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 L21SP4_RS05785 7599bf1778a243d141a975b80545d568 144 SUPERFAMILY SSF50249 3 144 4.11E-49 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold L21SP4_RS05785 7599bf1778a243d141a975b80545d568 144 PIRSF PIRSF002070 1 143 4.5E-39 T 22-04-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 L21SP4_RS05785 7599bf1778a243d141a975b80545d568 144 Gene3D G3DSA:2.40.50.140 1 144 3.9E-47 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold L21SP4_RS04510 4fdf7d0c0366f7daf9db99c4db568b1b 404 Pfam PF08388 Group II intron, maturase-specific domain 303 375 3.7E-15 T 22-04-2016 IPR013597 Group II intron, maturase-specific L21SP4_RS04510 4fdf7d0c0366f7daf9db99c4db568b1b 404 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 25 366 8.9E-114 T 22-04-2016 IPR030931 Group II intron reverse transcriptase/maturase L21SP4_RS04510 4fdf7d0c0366f7daf9db99c4db568b1b 404 PANTHER PTHR19446 39 330 6.4E-74 T 22-04-2016 L21SP4_RS04510 4fdf7d0c0366f7daf9db99c4db568b1b 404 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 81 290 4.0E-44 T 22-04-2016 IPR000477 Reverse transcriptase domain L21SP4_RS04510 4fdf7d0c0366f7daf9db99c4db568b1b 404 PANTHER PTHR19446:SF383 39 330 6.4E-74 T 22-04-2016 L21SP4_RS04510 4fdf7d0c0366f7daf9db99c4db568b1b 404 SUPERFAMILY SSF56672 31 343 3.76E-47 T 22-04-2016 L21SP4_RS05225 24d69cc21af30680e8feb9c3a4edbf4a 191 PANTHER PTHR23133:SF3 4 172 1.4E-42 T 22-04-2016 L21SP4_RS05225 24d69cc21af30680e8feb9c3a4edbf4a 191 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 7 147 6.9E-28 T 22-04-2016 IPR006549 HAD-superfamily hydrolase,subfamily IIIA L21SP4_RS05225 24d69cc21af30680e8feb9c3a4edbf4a 191 Gene3D G3DSA:3.40.50.1000 2 160 2.2E-48 T 22-04-2016 IPR023214 HAD-like domain L21SP4_RS05225 24d69cc21af30680e8feb9c3a4edbf4a 191 Pfam PF13242 HAD-hyrolase-like 103 148 6.1E-11 T 22-04-2016 L21SP4_RS05225 24d69cc21af30680e8feb9c3a4edbf4a 191 PANTHER PTHR23133 4 172 1.4E-42 T 22-04-2016 L21SP4_RS05225 24d69cc21af30680e8feb9c3a4edbf4a 191 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 6 146 2.2E-40 T 22-04-2016 IPR006543 Histidinol-phosphate phosphatase GO:0016791 L21SP4_RS05225 24d69cc21af30680e8feb9c3a4edbf4a 191 SUPERFAMILY SSF56784 4 159 1.36E-38 T 22-04-2016 IPR023214 HAD-like domain L21SP4_RS06775 aafc5eee6eefe4d43f28d4c4cb306164 211 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 30 167 3.8E-14 T 22-04-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: REACT_216 L21SP4_RS06775 aafc5eee6eefe4d43f28d4c4cb306164 211 SUPERFAMILY SSF48150 4 207 1.24E-52 T 22-04-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 L21SP4_RS06775 aafc5eee6eefe4d43f28d4c4cb306164 211 Gene3D G3DSA:1.10.340.30 17 123 1.4E-32 T 22-04-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 L21SP4_RS06775 aafc5eee6eefe4d43f28d4c4cb306164 211 Gene3D G3DSA:1.10.1670.10 124 198 9.0E-18 T 22-04-2016 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal L21SP4_RS06775 aafc5eee6eefe4d43f28d4c4cb306164 211 PANTHER PTHR10359:SF17 1 206 1.3E-78 T 22-04-2016 L21SP4_RS06775 aafc5eee6eefe4d43f28d4c4cb306164 211 PIRSF PIRSF001435 1 211 1.0E-68 T 22-04-2016 IPR005759 Endonuclease III GO:0003906|GO:0006284 L21SP4_RS06775 aafc5eee6eefe4d43f28d4c4cb306164 211 SMART SM00478 34 193 7.0E-25 T 22-04-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: REACT_216 L21SP4_RS06775 aafc5eee6eefe4d43f28d4c4cb306164 211 PANTHER PTHR10359 1 206 1.3E-78 T 22-04-2016 L21SP4_RS05795 99cbeca49c8b54f258b4180a8b9650e3 189 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 1 179 31.175 T 22-04-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 L21SP4_RS05795 99cbeca49c8b54f258b4180a8b9650e3 189 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 1 185 3.4E-50 T 22-04-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 L21SP4_RS05795 99cbeca49c8b54f258b4180a8b9650e3 189 Gene3D G3DSA:3.40.50.1470 1 187 1.4E-63 T 22-04-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 L21SP4_RS05795 99cbeca49c8b54f258b4180a8b9650e3 189 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 14 27 - T 22-04-2016 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 L21SP4_RS05795 99cbeca49c8b54f258b4180a8b9650e3 189 PANTHER PTHR17224 1 186 1.9E-69 T 22-04-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 L21SP4_RS05795 99cbeca49c8b54f258b4180a8b9650e3 189 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 108 118 - T 22-04-2016 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 L21SP4_RS05795 99cbeca49c8b54f258b4180a8b9650e3 189 Pfam PF01195 Peptidyl-tRNA hydrolase 4 183 1.6E-50 T 22-04-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 L21SP4_RS05795 99cbeca49c8b54f258b4180a8b9650e3 189 SUPERFAMILY SSF53178 1 186 1.7E-55 T 22-04-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 L21SP4_RS10325 d32ae6779a7369e7cf29ee991f1ddad2 1184 PANTHER PTHR18937 515 658 4.3E-233 T 22-04-2016 L21SP4_RS10325 d32ae6779a7369e7cf29ee991f1ddad2 1184 PANTHER PTHR18937 675 1177 4.3E-233 T 22-04-2016 L21SP4_RS10325 d32ae6779a7369e7cf29ee991f1ddad2 1184 Gene3D G3DSA:3.40.50.300 1044 1181 3.0E-65 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS10325 d32ae6779a7369e7cf29ee991f1ddad2 1184 Gene3D G3DSA:3.40.50.300 2 163 3.0E-65 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS10325 d32ae6779a7369e7cf29ee991f1ddad2 1184 Gene3D G3DSA:3.40.50.300 901 902 3.0E-65 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS10325 d32ae6779a7369e7cf29ee991f1ddad2 1184 PANTHER PTHR18937:SF261 675 1177 4.3E-233 T 22-04-2016 L21SP4_RS10325 d32ae6779a7369e7cf29ee991f1ddad2 1184 Pfam PF06470 SMC proteins Flexible Hinge Domain 526 627 1.9E-16 T 22-04-2016 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 L21SP4_RS10325 d32ae6779a7369e7cf29ee991f1ddad2 1184 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 2 1177 0.0 T 22-04-2016 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 L21SP4_RS10325 d32ae6779a7369e7cf29ee991f1ddad2 1184 SUPERFAMILY SSF52540 804 916 1.14E-29 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS10325 d32ae6779a7369e7cf29ee991f1ddad2 1184 SUPERFAMILY SSF52540 976 1178 1.14E-29 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS10325 d32ae6779a7369e7cf29ee991f1ddad2 1184 PANTHER PTHR18937:SF261 2 498 4.3E-233 T 22-04-2016 L21SP4_RS10325 d32ae6779a7369e7cf29ee991f1ddad2 1184 PANTHER PTHR18937 2 498 4.3E-233 T 22-04-2016 L21SP4_RS10325 d32ae6779a7369e7cf29ee991f1ddad2 1184 SMART SM00968 524 634 2.9E-9 T 22-04-2016 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 L21SP4_RS10325 d32ae6779a7369e7cf29ee991f1ddad2 1184 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 1171 9.4E-65 T 22-04-2016 IPR003395 RecF/RecN/SMC, N-terminal L21SP4_RS10325 d32ae6779a7369e7cf29ee991f1ddad2 1184 SUPERFAMILY SSF75553 488 652 4.32E-16 T 22-04-2016 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 L21SP4_RS10325 d32ae6779a7369e7cf29ee991f1ddad2 1184 PANTHER PTHR18937:SF261 515 658 4.3E-233 T 22-04-2016 L21SP4_RS10325 d32ae6779a7369e7cf29ee991f1ddad2 1184 SUPERFAMILY SSF52540 1077 1163 9.0E-46 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS10325 d32ae6779a7369e7cf29ee991f1ddad2 1184 SUPERFAMILY SSF52540 2 214 9.0E-46 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS10325 d32ae6779a7369e7cf29ee991f1ddad2 1184 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1180 22.052 T 22-04-2016 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 L21SP4_RS10325 d32ae6779a7369e7cf29ee991f1ddad2 1184 PIRSF PIRSF005719 1 1183 9.7E-276 T 22-04-2016 IPR024704 Structural maintenance of chromosomes protein L21SP4_RS05660 3e73ca35079a404510c7daf053e88e14 259 Gene3D G3DSA:3.30.1330.30 5 103 4.7E-10 T 22-04-2016 IPR029064 50S ribosomal protein L30e-like L21SP4_RS05660 3e73ca35079a404510c7daf053e88e14 259 Gene3D G3DSA:3.40.1280.10 112 258 7.9E-42 T 22-04-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal L21SP4_RS05660 3e73ca35079a404510c7daf053e88e14 259 SUPERFAMILY SSF75217 108 258 4.77E-37 T 22-04-2016 IPR029028 Alpha/beta knot methyltransferases L21SP4_RS05660 3e73ca35079a404510c7daf053e88e14 259 SUPERFAMILY SSF55315 4 104 8.24E-10 T 22-04-2016 IPR029064 50S ribosomal protein L30e-like L21SP4_RS05660 3e73ca35079a404510c7daf053e88e14 259 PANTHER PTHR12029 4 258 1.2E-45 T 22-04-2016 L21SP4_RS05660 3e73ca35079a404510c7daf053e88e14 259 Pfam PF00588 SpoU rRNA Methylase family 117 254 9.3E-32 T 22-04-2016 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 L21SP4_RS02220 81407eb197b4b1f1da6e05e2e8e9125e 427 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 142 162 - T 22-04-2016 IPR020612 Methylthiotransferase, conserved site GO:0051539 L21SP4_RS02220 81407eb197b4b1f1da6e05e2e8e9125e 427 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 4 424 2.9E-125 T 22-04-2016 IPR005839 Methylthiotransferase GO:0016740|GO:0043412|GO:0051539 L21SP4_RS02220 81407eb197b4b1f1da6e05e2e8e9125e 427 Gene3D G3DSA:3.80.30.20 136 363 1.2E-72 T 22-04-2016 IPR023404 Radical SAM, alpha/beta horseshoe L21SP4_RS02220 81407eb197b4b1f1da6e05e2e8e9125e 427 SUPERFAMILY SSF102114 136 359 3.14E-58 T 22-04-2016 L21SP4_RS02220 81407eb197b4b1f1da6e05e2e8e9125e 427 Pfam PF00919 Uncharacterized protein family UPF0004 5 103 2.2E-22 T 22-04-2016 IPR013848 Methylthiotransferase, N-terminal GO:0003824|GO:0009451|GO:0051539 L21SP4_RS02220 81407eb197b4b1f1da6e05e2e8e9125e 427 PANTHER PTHR11918 1 426 3.0E-136 T 22-04-2016 IPR023970 Methylthiotransferase/radical SAM-type protein L21SP4_RS02220 81407eb197b4b1f1da6e05e2e8e9125e 427 Pfam PF04055 Radical SAM superfamily 142 312 2.4E-27 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 L21SP4_RS02220 81407eb197b4b1f1da6e05e2e8e9125e 427 PANTHER PTHR11918:SF43 1 426 3.0E-136 T 22-04-2016 L21SP4_RS02220 81407eb197b4b1f1da6e05e2e8e9125e 427 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 4 421 4.2E-110 T 22-04-2016 L21SP4_RS02220 81407eb197b4b1f1da6e05e2e8e9125e 427 SMART SM00729 138 355 4.5E-60 T 22-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 L21SP4_RS06470 a06b5ff9cd252cf4ff776aaf141ce51a 1049 Pfam PF12969 Domain of Unknown Function with PDB structure (DUF3857) 53 225 2.0E-24 T 22-04-2016 IPR024618 Domain of unknown function DUF3857 L21SP4_RS06470 a06b5ff9cd252cf4ff776aaf141ce51a 1049 Pfam PF12969 Domain of Unknown Function with PDB structure (DUF3857) 670 829 3.5E-24 T 22-04-2016 IPR024618 Domain of unknown function DUF3857 L21SP4_RS06470 a06b5ff9cd252cf4ff776aaf141ce51a 1049 Pfam PF01841 Transglutaminase-like superfamily 276 387 2.0E-10 T 22-04-2016 IPR002931 Transglutaminase-like L21SP4_RS06470 a06b5ff9cd252cf4ff776aaf141ce51a 1049 SUPERFAMILY SSF54001 876 956 4.71E-6 T 22-04-2016 L21SP4_RS06470 a06b5ff9cd252cf4ff776aaf141ce51a 1049 SUPERFAMILY SSF54001 266 406 1.47E-15 T 22-04-2016 L21SP4_RS05035 960fdb30a0ce611bb047a2e46da697e7 326 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 133 149 1.5E-38 T 22-04-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 L21SP4_RS05035 960fdb30a0ce611bb047a2e46da697e7 326 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 112 130 1.5E-38 T 22-04-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 L21SP4_RS05035 960fdb30a0ce611bb047a2e46da697e7 326 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 196 205 1.5E-38 T 22-04-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 L21SP4_RS05035 960fdb30a0ce611bb047a2e46da697e7 326 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 168 181 1.5E-38 T 22-04-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 L21SP4_RS05035 960fdb30a0ce611bb047a2e46da697e7 326 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 87 98 1.5E-38 T 22-04-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 L21SP4_RS05035 960fdb30a0ce611bb047a2e46da697e7 326 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 152 165 1.5E-38 T 22-04-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 L21SP4_RS05035 960fdb30a0ce611bb047a2e46da697e7 326 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 5 147 6.5E-60 T 22-04-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 L21SP4_RS05035 960fdb30a0ce611bb047a2e46da697e7 326 SUPERFAMILY SSF52096 7 315 2.7E-97 T 22-04-2016 IPR029045 ClpP/crotonase-like domain L21SP4_RS05035 960fdb30a0ce611bb047a2e46da697e7 326 PANTHER PTHR22855 5 317 3.9E-122 T 22-04-2016 L21SP4_RS05035 960fdb30a0ce611bb047a2e46da697e7 326 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 5 319 2.1E-135 T 22-04-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 L21SP4_RS05035 960fdb30a0ce611bb047a2e46da697e7 326 Gene3D G3DSA:3.90.226.10 55 293 1.7E-46 T 22-04-2016 IPR029045 ClpP/crotonase-like domain L21SP4_RS05035 960fdb30a0ce611bb047a2e46da697e7 326 PANTHER PTHR22855:SF42 5 317 3.9E-122 T 22-04-2016 L21SP4_RS05035 960fdb30a0ce611bb047a2e46da697e7 326 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 4 315 47.632 T 22-04-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 L21SP4_RS06040 b0f567534974226607879d9cd8653d5c 635 Gene3D G3DSA:3.20.20.80 113 374 7.0E-19 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP4_RS06040 b0f567534974226607879d9cd8653d5c 635 Pfam PF01229 Glycosyl hydrolases family 39 140 319 7.0E-18 T 22-04-2016 IPR000514 Glycoside hydrolase, family 39 GO:0004553|GO:0005975 L21SP4_RS06040 b0f567534974226607879d9cd8653d5c 635 SUPERFAMILY SSF51445 143 424 3.64E-14 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily L21SP4_RS08815 7dafb730f8944b6d348bdc73616423ac 364 PANTHER PTHR12526 2 364 7.3E-63 T 22-04-2016 L21SP4_RS08815 7dafb730f8944b6d348bdc73616423ac 364 Gene3D G3DSA:3.40.50.2000 182 333 3.2E-32 T 22-04-2016 L21SP4_RS08815 7dafb730f8944b6d348bdc73616423ac 364 Pfam PF13439 Glycosyltransferase Family 4 16 172 1.2E-13 T 22-04-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain L21SP4_RS08815 7dafb730f8944b6d348bdc73616423ac 364 Pfam PF00534 Glycosyl transferases group 1 184 335 1.1E-35 T 22-04-2016 IPR001296 Glycosyl transferase, family 1 L21SP4_RS08815 7dafb730f8944b6d348bdc73616423ac 364 SUPERFAMILY SSF53756 2 360 8.9E-73 T 22-04-2016 L21SP4_RS00755 b3ee7d2ab130c6b086adb4b1bcbd2140 236 SMART SM00382 26 214 7.3E-7 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS00755 b3ee7d2ab130c6b086adb4b1bcbd2140 236 SUPERFAMILY SSF52540 1 228 1.54E-59 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS00755 b3ee7d2ab130c6b086adb4b1bcbd2140 236 PANTHER PTHR24220 3 236 2.2E-95 T 22-04-2016 L21SP4_RS00755 b3ee7d2ab130c6b086adb4b1bcbd2140 236 Gene3D G3DSA:3.40.50.300 1 227 1.0E-65 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS00755 b3ee7d2ab130c6b086adb4b1bcbd2140 236 PANTHER PTHR24220:SF567 3 236 2.2E-95 T 22-04-2016 L21SP4_RS00755 b3ee7d2ab130c6b086adb4b1bcbd2140 236 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 L21SP4_RS00755 b3ee7d2ab130c6b086adb4b1bcbd2140 236 Pfam PF00005 ABC transporter 18 164 9.8E-27 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 L21SP4_RS02100 1f9c77924dcaf9130a2857470f84bee2 479 Pfam PF00884 Sulfatase 2 310 7.4E-49 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS02100 1f9c77924dcaf9130a2857470f84bee2 479 PANTHER PTHR10342 1 476 3.1E-85 T 22-04-2016 L21SP4_RS02100 1f9c77924dcaf9130a2857470f84bee2 479 Gene3D G3DSA:3.30.1120.10 350 372 5.0E-12 T 22-04-2016 L21SP4_RS02100 1f9c77924dcaf9130a2857470f84bee2 479 Gene3D G3DSA:3.30.1120.10 417 464 5.0E-12 T 22-04-2016 L21SP4_RS02100 1f9c77924dcaf9130a2857470f84bee2 479 SUPERFAMILY SSF53649 2 370 1.6E-96 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS02100 1f9c77924dcaf9130a2857470f84bee2 479 SUPERFAMILY SSF53649 415 461 1.6E-96 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS02100 1f9c77924dcaf9130a2857470f84bee2 479 Gene3D G3DSA:3.40.720.10 2 330 5.5E-74 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS09775 c5b745e2fc89003c6e52deae62e384ef 275 PANTHER PTHR24322 17 152 3.2E-42 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS09775 c5b745e2fc89003c6e52deae62e384ef 275 PANTHER PTHR24322 168 203 3.2E-42 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS09775 c5b745e2fc89003c6e52deae62e384ef 275 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 25 270 2.0E-40 T 22-04-2016 L21SP4_RS09775 c5b745e2fc89003c6e52deae62e384ef 275 SUPERFAMILY SSF51735 12 270 3.74E-59 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS09775 c5b745e2fc89003c6e52deae62e384ef 275 PANTHER PTHR24322:SF625 17 152 3.2E-42 T 22-04-2016 L21SP4_RS09775 c5b745e2fc89003c6e52deae62e384ef 275 PANTHER PTHR24322:SF625 168 203 3.2E-42 T 22-04-2016 L21SP4_RS09775 c5b745e2fc89003c6e52deae62e384ef 275 Gene3D G3DSA:3.40.50.720 8 270 3.9E-60 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS09775 c5b745e2fc89003c6e52deae62e384ef 275 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 155 183 - T 22-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 L21SP4_RS09775 c5b745e2fc89003c6e52deae62e384ef 275 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 156 1.6E-9 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS09775 c5b745e2fc89003c6e52deae62e384ef 275 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 168 187 1.6E-9 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS09775 c5b745e2fc89003c6e52deae62e384ef 275 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 88 99 1.6E-9 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS09775 c5b745e2fc89003c6e52deae62e384ef 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 142 158 2.4E-31 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS09775 c5b745e2fc89003c6e52deae62e384ef 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 192 209 2.4E-31 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS09775 c5b745e2fc89003c6e52deae62e384ef 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 187 2.4E-31 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS09775 c5b745e2fc89003c6e52deae62e384ef 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 2.4E-31 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS09775 c5b745e2fc89003c6e52deae62e384ef 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 2.4E-31 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS09775 c5b745e2fc89003c6e52deae62e384ef 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 232 252 2.4E-31 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS08995 57e7498dfd5ae8e4ce214430984f38ca 325 Gene3D G3DSA:3.90.550.10 16 145 1.1E-27 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases L21SP4_RS08995 57e7498dfd5ae8e4ce214430984f38ca 325 Pfam PF00535 Glycosyl transferase family 2 17 148 1.7E-31 T 22-04-2016 IPR001173 Glycosyltransferase 2-like L21SP4_RS08995 57e7498dfd5ae8e4ce214430984f38ca 325 SUPERFAMILY SSF53448 16 269 4.31E-42 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases L21SP4_RS08995 57e7498dfd5ae8e4ce214430984f38ca 325 PANTHER PTHR10859 1 325 6.7E-108 T 22-04-2016 L21SP4_RS08995 57e7498dfd5ae8e4ce214430984f38ca 325 PANTHER PTHR10859:SF49 1 325 6.7E-108 T 22-04-2016 L21SP4_RS07940 a72d62e8642327bf7b561c0f22b443c6 237 Gene3D G3DSA:3.90.470.20 32 129 7.2E-25 T 22-04-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 L21SP4_RS07940 a72d62e8642327bf7b561c0f22b443c6 237 PANTHER PTHR12215 32 172 1.5E-21 T 22-04-2016 L21SP4_RS07940 a72d62e8642327bf7b561c0f22b443c6 237 SUPERFAMILY SSF56214 118 218 2.44E-9 T 22-04-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 L21SP4_RS07940 a72d62e8642327bf7b561c0f22b443c6 237 PANTHER PTHR12215:SF10 32 172 1.5E-21 T 22-04-2016 L21SP4_RS07940 a72d62e8642327bf7b561c0f22b443c6 237 Gene3D G3DSA:3.90.470.20 130 174 3.5E-5 T 22-04-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 L21SP4_RS07940 a72d62e8642327bf7b561c0f22b443c6 237 SUPERFAMILY SSF56214 22 110 4.19E-18 T 22-04-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 L21SP4_RS01730 f7aeab36c076c110199d7837776aaa0e 252 Pfam PF00731 AIR carboxylase 119 244 8.9E-11 T 22-04-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 L21SP4_RS01730 f7aeab36c076c110199d7837776aaa0e 252 PANTHER PTHR23046 2 251 1.4E-106 T 22-04-2016 L21SP4_RS01730 f7aeab36c076c110199d7837776aaa0e 252 Gene3D G3DSA:3.40.50.7700 118 245 8.6E-19 T 22-04-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 L21SP4_RS01730 f7aeab36c076c110199d7837776aaa0e 252 SUPERFAMILY SSF52255 118 247 7.06E-23 T 22-04-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 L21SP4_RS01730 f7aeab36c076c110199d7837776aaa0e 252 PANTHER PTHR23046:SF3 2 251 1.4E-106 T 22-04-2016 L21SP4_RS01730 f7aeab36c076c110199d7837776aaa0e 252 SMART SM01001 118 250 3.5E-29 T 22-04-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 L21SP4_RS02430 04cd8b90dc2846be6eed8fe9fe2dc562 690 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 589 672 1.6E-12 T 22-04-2016 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: REACT_474 L21SP4_RS02430 04cd8b90dc2846be6eed8fe9fe2dc562 690 PANTHER PTHR10357 19 674 3.1E-236 T 22-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 L21SP4_RS02430 04cd8b90dc2846be6eed8fe9fe2dc562 690 SUPERFAMILY SSF51445 162 573 5.73E-82 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily L21SP4_RS02430 04cd8b90dc2846be6eed8fe9fe2dc562 690 PIRSF PIRSF000463 3 678 1.9E-175 T 22-04-2016 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|UniPathway: UPA00164 L21SP4_RS02430 04cd8b90dc2846be6eed8fe9fe2dc562 690 PANTHER PTHR10357:SF110 19 674 3.1E-236 T 22-04-2016 L21SP4_RS02430 04cd8b90dc2846be6eed8fe9fe2dc562 690 Gene3D G3DSA:2.60.40.10 55 153 1.5E-20 T 22-04-2016 IPR013783 Immunoglobulin-like fold L21SP4_RS02430 04cd8b90dc2846be6eed8fe9fe2dc562 690 Pfam PF00128 Alpha amylase, catalytic domain 229 276 6.1E-8 T 22-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 L21SP4_RS02430 04cd8b90dc2846be6eed8fe9fe2dc562 690 SUPERFAMILY SSF81296 56 162 1.07E-17 T 22-04-2016 IPR014756 Immunoglobulin E-set L21SP4_RS02430 04cd8b90dc2846be6eed8fe9fe2dc562 690 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 63 133 1.2E-9 T 22-04-2016 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 L21SP4_RS02430 04cd8b90dc2846be6eed8fe9fe2dc562 690 Gene3D G3DSA:2.60.40.1180 589 672 3.3E-7 T 22-04-2016 IPR013780 Glycosyl hydrolase, all-beta L21SP4_RS02430 04cd8b90dc2846be6eed8fe9fe2dc562 690 SMART SM00642 123 550 2.2E-5 T 22-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 L21SP4_RS02430 04cd8b90dc2846be6eed8fe9fe2dc562 690 Gene3D G3DSA:3.20.20.80 169 572 2.2E-72 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP4_RS02430 04cd8b90dc2846be6eed8fe9fe2dc562 690 SUPERFAMILY SSF51011 588 672 7.91E-10 T 22-04-2016 L21SP4_RS00770 8295a0c3d28ccd62d179c24628620490 397 SUPERFAMILY SSF53649 1 369 3.05E-96 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS00770 8295a0c3d28ccd62d179c24628620490 397 Pfam PF00884 Sulfatase 1 296 7.1E-53 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS00770 8295a0c3d28ccd62d179c24628620490 397 PANTHER PTHR10342:SF199 1 367 3.1E-91 T 22-04-2016 L21SP4_RS00770 8295a0c3d28ccd62d179c24628620490 397 Gene3D G3DSA:3.30.1120.10 338 384 1.2E-4 T 22-04-2016 L21SP4_RS00770 8295a0c3d28ccd62d179c24628620490 397 Gene3D G3DSA:3.40.720.10 1 337 1.1E-86 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS00770 8295a0c3d28ccd62d179c24628620490 397 ProSitePatterns PS00523 Sulfatases signature 1. 42 54 - T 22-04-2016 IPR024607 Sulfatase, conserved site L21SP4_RS00770 8295a0c3d28ccd62d179c24628620490 397 PANTHER PTHR10342 1 367 3.1E-91 T 22-04-2016 L21SP4_RS03465 0b9fdcbea2131f0d910bfaa1242afb87 305 SUPERFAMILY SSF53850 91 297 7.96E-33 T 22-04-2016 L21SP4_RS03465 0b9fdcbea2131f0d910bfaa1242afb87 305 Gene3D G3DSA:1.10.10.10 8 89 7.5E-22 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS03465 0b9fdcbea2131f0d910bfaa1242afb87 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 1.1E-8 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 L21SP4_RS03465 0b9fdcbea2131f0d910bfaa1242afb87 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 1.1E-8 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 L21SP4_RS03465 0b9fdcbea2131f0d910bfaa1242afb87 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 1.1E-8 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 L21SP4_RS03465 0b9fdcbea2131f0d910bfaa1242afb87 305 Pfam PF03466 LysR substrate binding domain 90 295 1.3E-28 T 22-04-2016 IPR005119 LysR, substrate-binding L21SP4_RS03465 0b9fdcbea2131f0d910bfaa1242afb87 305 Gene3D G3DSA:3.40.190.10 91 183 8.6E-14 T 22-04-2016 L21SP4_RS03465 0b9fdcbea2131f0d910bfaa1242afb87 305 PANTHER PTHR30126:SF25 4 305 1.8E-131 T 22-04-2016 L21SP4_RS03465 0b9fdcbea2131f0d910bfaa1242afb87 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 65 1.7E-17 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 L21SP4_RS03465 0b9fdcbea2131f0d910bfaa1242afb87 305 SUPERFAMILY SSF46785 8 111 2.3E-19 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS03465 0b9fdcbea2131f0d910bfaa1242afb87 305 PANTHER PTHR30126 4 305 1.8E-131 T 22-04-2016 L21SP4_RS03465 0b9fdcbea2131f0d910bfaa1242afb87 305 Gene3D G3DSA:3.40.190.10 184 253 2.6E-15 T 22-04-2016 L21SP4_RS08375 f90cc4cce234eff56b6c90d4ded07954 211 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 206 34.345 T 22-04-2016 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 L21SP4_RS08375 f90cc4cce234eff56b6c90d4ded07954 211 SMART SM00322 60 125 2.9E-5 T 22-04-2016 IPR004087 K Homology domain GO:0003676 L21SP4_RS08375 f90cc4cce234eff56b6c90d4ded07954 211 SUPERFAMILY SSF54821 107 205 3.66E-35 T 22-04-2016 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 L21SP4_RS08375 f90cc4cce234eff56b6c90d4ded07954 211 Pfam PF00189 Ribosomal protein S3, C-terminal domain 120 202 3.1E-35 T 22-04-2016 L21SP4_RS08375 f90cc4cce234eff56b6c90d4ded07954 211 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 207 9.6E-85 T 22-04-2016 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 L21SP4_RS08375 f90cc4cce234eff56b6c90d4ded07954 211 SUPERFAMILY SSF54814 2 106 6.28E-35 T 22-04-2016 IPR009019 K homology domain, prokaryotic type GO:0003723 L21SP4_RS08375 f90cc4cce234eff56b6c90d4ded07954 211 Gene3D G3DSA:3.30.300.20 17 107 2.0E-29 T 22-04-2016 IPR015946 K homology domain-like, alpha/beta L21SP4_RS08375 f90cc4cce234eff56b6c90d4ded07954 211 Pfam PF07650 KH domain 39 110 6.9E-18 T 22-04-2016 IPR004044 K Homology domain, type 2 GO:0003723 L21SP4_RS08375 f90cc4cce234eff56b6c90d4ded07954 211 PANTHER PTHR11760:SF19 2 206 2.9E-109 T 22-04-2016 L21SP4_RS08375 f90cc4cce234eff56b6c90d4ded07954 211 Gene3D G3DSA:3.30.1140.32 109 206 1.9E-39 T 22-04-2016 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 L21SP4_RS08375 f90cc4cce234eff56b6c90d4ded07954 211 PANTHER PTHR11760 2 206 2.9E-109 T 22-04-2016 L21SP4_RS04115 6642736e3600b21fecca4995ddc6b0a2 373 SUPERFAMILY SSF102114 3 373 9.68E-113 T 22-04-2016 L21SP4_RS04115 6642736e3600b21fecca4995ddc6b0a2 373 Gene3D G3DSA:3.80.30.20 4 235 2.0E-42 T 22-04-2016 IPR023404 Radical SAM, alpha/beta horseshoe L21SP4_RS04115 6642736e3600b21fecca4995ddc6b0a2 373 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 4 349 9.1E-86 T 22-04-2016 IPR004559 Coproporphyrinogen III oxidase, oxygen-independent related GO:0004109|GO:0005737|GO:0006779|GO:0055114 KEGG: 00071+1.3.99.-|KEGG: 00280+1.3.99.-|KEGG: 00281+1.3.99.-|KEGG: 00362+1.3.99.-|KEGG: 00626+1.3.99.-|KEGG: 00930+1.3.99.- L21SP4_RS04115 6642736e3600b21fecca4995ddc6b0a2 373 PANTHER PTHR13932 3 373 3.5E-133 T 22-04-2016 L21SP4_RS04115 6642736e3600b21fecca4995ddc6b0a2 373 SMART SM00729 1 219 1.7E-49 T 22-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 L21SP4_RS04115 6642736e3600b21fecca4995ddc6b0a2 373 PANTHER PTHR13932:SF5 3 373 3.5E-133 T 22-04-2016 L21SP4_RS04115 6642736e3600b21fecca4995ddc6b0a2 373 Pfam PF04055 Radical SAM superfamily 6 174 3.2E-23 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 L21SP4_RS04115 6642736e3600b21fecca4995ddc6b0a2 373 Pfam PF06969 HemN C-terminal domain 300 362 7.8E-11 T 22-04-2016 IPR010723 HemN, C-terminal L21SP4_RS00725 9806ea96a68a8c1c1110dc7df403ba3a 276 SUPERFAMILY SSF53474 29 266 2.61E-47 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold L21SP4_RS00725 9806ea96a68a8c1c1110dc7df403ba3a 276 Pfam PF01738 Dienelactone hydrolase family 205 254 7.0E-9 T 22-04-2016 IPR002925 Dienelactone hydrolase GO:0016787 L21SP4_RS00725 9806ea96a68a8c1c1110dc7df403ba3a 276 Pfam PF07859 alpha/beta hydrolase fold 59 179 8.4E-15 T 22-04-2016 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 L21SP4_RS00725 9806ea96a68a8c1c1110dc7df403ba3a 276 PANTHER PTHR23024 41 272 4.3E-79 T 22-04-2016 L21SP4_RS00725 9806ea96a68a8c1c1110dc7df403ba3a 276 Gene3D G3DSA:3.40.50.1820 33 268 6.3E-61 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold L21SP4_RS00725 9806ea96a68a8c1c1110dc7df403ba3a 276 PANTHER PTHR23024:SF58 41 272 4.3E-79 T 22-04-2016 L21SP4_RS01385 e58a396f7bb0dd82b3f85e91a7768ae9 285 SUPERFAMILY SSF109998 3 152 8.04E-21 T 22-04-2016 IPR027304 Trigger factor/SurA domain L21SP4_RS01385 e58a396f7bb0dd82b3f85e91a7768ae9 285 PANTHER PTHR10657 3 281 6.6E-52 T 22-04-2016 L21SP4_RS01385 e58a396f7bb0dd82b3f85e91a7768ae9 285 Pfam PF13616 PPIC-type PPIASE domain 137 235 4.4E-21 T 22-04-2016 L21SP4_RS01385 e58a396f7bb0dd82b3f85e91a7768ae9 285 SUPERFAMILY SSF54534 131 232 1.64E-25 T 22-04-2016 L21SP4_RS01385 e58a396f7bb0dd82b3f85e91a7768ae9 285 Gene3D G3DSA:3.10.50.40 131 256 5.3E-39 T 22-04-2016 L21SP4_RS01385 e58a396f7bb0dd82b3f85e91a7768ae9 285 PANTHER PTHR10657:SF11 3 281 6.6E-52 T 22-04-2016 L21SP4_RS02755 9ed2a596a3d64d75dff7994ca8f3a53a 652 PANTHER PTHR30290 289 624 9.2E-98 T 22-04-2016 L21SP4_RS02755 9ed2a596a3d64d75dff7994ca8f3a53a 652 PANTHER PTHR30290 6 263 9.2E-98 T 22-04-2016 L21SP4_RS02755 9ed2a596a3d64d75dff7994ca8f3a53a 652 SUPERFAMILY SSF53850 47 603 1.18E-103 T 22-04-2016 L21SP4_RS02755 9ed2a596a3d64d75dff7994ca8f3a53a 652 Gene3D G3DSA:3.10.105.10 353 581 5.6E-44 T 22-04-2016 L21SP4_RS02755 9ed2a596a3d64d75dff7994ca8f3a53a 652 PIRSF PIRSF002741 18 611 4.0E-76 T 22-04-2016 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 L21SP4_RS02755 9ed2a596a3d64d75dff7994ca8f3a53a 652 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 90 529 3.2E-70 T 22-04-2016 IPR000914 Solute-binding protein family 5 domain L21SP4_RS02755 9ed2a596a3d64d75dff7994ca8f3a53a 652 Gene3D G3DSA:3.90.76.10 55 247 7.0E-41 T 22-04-2016 L21SP4_RS09375 6f03eb0bc14c1a1e2e6d12a063be4d17 955 Pfam PF09261 Alpha mannosidase middle domain 340 416 8.5E-6 T 22-04-2016 IPR015341 Glycoside hydrolase family 38, central domain GO:0004553|GO:0008270 L21SP4_RS09375 6f03eb0bc14c1a1e2e6d12a063be4d17 955 Gene3D G3DSA:3.20.110.10 5 327 5.0E-38 T 22-04-2016 IPR027291 Glycoside hydrolase 38/57, N-terminal domain L21SP4_RS09375 6f03eb0bc14c1a1e2e6d12a063be4d17 955 Pfam PF01074 Glycosyl hydrolases family 38 N-terminal domain 10 308 8.8E-33 T 22-04-2016 IPR000602 Glycoside hydrolase family 38, N-terminal domain GO:0004559|GO:0005975 L21SP4_RS09375 6f03eb0bc14c1a1e2e6d12a063be4d17 955 Pfam PF07748 Glycosyl hydrolases family 38 C-terminal domain 450 917 1.7E-30 T 22-04-2016 IPR011682 Glycosyl hydrolase family 38, C-terminal GO:0006013|GO:0015923 L21SP4_RS09375 6f03eb0bc14c1a1e2e6d12a063be4d17 955 PANTHER PTHR11607:SF26 206 470 1.5E-94 T 22-04-2016 L21SP4_RS09375 6f03eb0bc14c1a1e2e6d12a063be4d17 955 PANTHER PTHR11607:SF26 488 647 1.5E-94 T 22-04-2016 L21SP4_RS09375 6f03eb0bc14c1a1e2e6d12a063be4d17 955 PANTHER PTHR11607:SF26 10 189 1.5E-94 T 22-04-2016 L21SP4_RS09375 6f03eb0bc14c1a1e2e6d12a063be4d17 955 PANTHER PTHR11607:SF26 675 799 1.5E-94 T 22-04-2016 L21SP4_RS09375 6f03eb0bc14c1a1e2e6d12a063be4d17 955 SUPERFAMILY SSF88713 3 276 9.78E-38 T 22-04-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 L21SP4_RS09375 6f03eb0bc14c1a1e2e6d12a063be4d17 955 SMART SM00872 338 416 2.4E-5 T 22-04-2016 IPR015341 Glycoside hydrolase family 38, central domain GO:0004553|GO:0008270 L21SP4_RS09375 6f03eb0bc14c1a1e2e6d12a063be4d17 955 Gene3D G3DSA:2.60.40.1180 438 559 4.9E-13 T 22-04-2016 IPR013780 Glycosyl hydrolase, all-beta L21SP4_RS09375 6f03eb0bc14c1a1e2e6d12a063be4d17 955 PANTHER PTHR11607 206 470 1.5E-94 T 22-04-2016 L21SP4_RS09375 6f03eb0bc14c1a1e2e6d12a063be4d17 955 PANTHER PTHR11607 488 647 1.5E-94 T 22-04-2016 L21SP4_RS09375 6f03eb0bc14c1a1e2e6d12a063be4d17 955 PANTHER PTHR11607 10 189 1.5E-94 T 22-04-2016 L21SP4_RS09375 6f03eb0bc14c1a1e2e6d12a063be4d17 955 PANTHER PTHR11607 675 799 1.5E-94 T 22-04-2016 L21SP4_RS09375 6f03eb0bc14c1a1e2e6d12a063be4d17 955 Gene3D G3DSA:1.20.1270.50 340 429 1.1E-8 T 22-04-2016 IPR015341 Glycoside hydrolase family 38, central domain GO:0004553|GO:0008270 L21SP4_RS09375 6f03eb0bc14c1a1e2e6d12a063be4d17 955 SUPERFAMILY SSF88688 339 432 1.73E-9 T 22-04-2016 IPR028995 Glycoside hydrolase families 57/38, central domain L21SP4_RS09375 6f03eb0bc14c1a1e2e6d12a063be4d17 955 SUPERFAMILY SSF74650 443 646 8.79E-56 T 22-04-2016 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 L21SP4_RS09375 6f03eb0bc14c1a1e2e6d12a063be4d17 955 SUPERFAMILY SSF74650 682 925 8.79E-56 T 22-04-2016 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 L21SP4_RS02615 dc389db316749add4f992e0db3009665 753 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 486 608 5.5E-18 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS02615 dc389db316749add4f992e0db3009665 753 Pfam PF00072 Response regulator receiver domain 632 743 1.2E-20 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 L21SP4_RS02615 dc389db316749add4f992e0db3009665 753 Pfam PF00072 Response regulator receiver domain 3 115 1.4E-26 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 L21SP4_RS02615 dc389db316749add4f992e0db3009665 753 Pfam PF00989 PAS fold 249 359 7.3E-15 T 22-04-2016 IPR013767 PAS fold GO:0006355 L21SP4_RS02615 dc389db316749add4f992e0db3009665 753 Pfam PF00512 His Kinase A (phospho-acceptor) domain 378 440 4.8E-7 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS02615 dc389db316749add4f992e0db3009665 753 SMART SM00448 630 743 1.0E-23 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 L21SP4_RS02615 dc389db316749add4f992e0db3009665 753 SMART SM00448 1 115 3.2E-41 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 L21SP4_RS02615 dc389db316749add4f992e0db3009665 753 SMART SM00388 377 443 1.2E-8 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS02615 dc389db316749add4f992e0db3009665 753 SUPERFAMILY SSF55874 433 608 1.14E-39 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS02615 dc389db316749add4f992e0db3009665 753 Gene3D G3DSA:3.30.450.20 238 353 1.5E-27 T 22-04-2016 L21SP4_RS02615 dc389db316749add4f992e0db3009665 753 SUPERFAMILY SSF55785 253 360 3.32E-26 T 22-04-2016 IPR000014 PAS domain L21SP4_RS02615 dc389db316749add4f992e0db3009665 753 SUPERFAMILY SSF52172 1 125 1.2E-36 T 22-04-2016 IPR011006 CheY-like superfamily L21SP4_RS02615 dc389db316749add4f992e0db3009665 753 Gene3D G3DSA:3.40.50.2300 1 115 2.2E-36 T 22-04-2016 L21SP4_RS02615 dc389db316749add4f992e0db3009665 753 SMART SM00091 248 314 2.8E-8 T 22-04-2016 IPR000014 PAS domain L21SP4_RS02615 dc389db316749add4f992e0db3009665 753 SMART SM00091 126 192 1.2E-7 T 22-04-2016 IPR000014 PAS domain L21SP4_RS02615 dc389db316749add4f992e0db3009665 753 SUPERFAMILY SSF47384 366 440 2.55E-10 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS02615 dc389db316749add4f992e0db3009665 753 Gene3D G3DSA:3.40.50.2300 629 748 3.7E-33 T 22-04-2016 L21SP4_RS02615 dc389db316749add4f992e0db3009665 753 Pfam PF08448 PAS fold 133 242 5.9E-15 T 22-04-2016 IPR013656 PAS fold-4 L21SP4_RS02615 dc389db316749add4f992e0db3009665 753 SUPERFAMILY SSF55785 114 238 1.48E-19 T 22-04-2016 IPR000014 PAS domain L21SP4_RS02615 dc389db316749add4f992e0db3009665 753 Gene3D G3DSA:3.30.450.20 116 237 1.7E-20 T 22-04-2016 L21SP4_RS02615 dc389db316749add4f992e0db3009665 753 SMART SM00387 484 610 5.7E-27 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS02615 dc389db316749add4f992e0db3009665 753 PRINTS PR00344 Bacterial sensor protein C-terminal signature 594 607 1.9E-19 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS02615 dc389db316749add4f992e0db3009665 753 PRINTS PR00344 Bacterial sensor protein C-terminal signature 539 553 1.9E-19 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS02615 dc389db316749add4f992e0db3009665 753 PRINTS PR00344 Bacterial sensor protein C-terminal signature 570 588 1.9E-19 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS02615 dc389db316749add4f992e0db3009665 753 PRINTS PR00344 Bacterial sensor protein C-terminal signature 557 567 1.9E-19 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS02615 dc389db316749add4f992e0db3009665 753 SMART SM00086 320 362 1.4E-5 T 22-04-2016 IPR001610 PAC motif L21SP4_RS02615 dc389db316749add4f992e0db3009665 753 SMART SM00086 198 240 110.0 T 22-04-2016 IPR001610 PAC motif L21SP4_RS02615 dc389db316749add4f992e0db3009665 753 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 246 369 9.7E-23 T 22-04-2016 IPR000014 PAS domain L21SP4_RS02615 dc389db316749add4f992e0db3009665 753 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 123 246 6.4E-15 T 22-04-2016 IPR000014 PAS domain L21SP4_RS02615 dc389db316749add4f992e0db3009665 753 Gene3D G3DSA:3.30.565.10 443 607 5.1E-38 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS02615 dc389db316749add4f992e0db3009665 753 PANTHER PTHR24423 119 747 1.9E-182 T 22-04-2016 L21SP4_RS02615 dc389db316749add4f992e0db3009665 753 SUPERFAMILY SSF52172 629 748 1.27E-30 T 22-04-2016 IPR011006 CheY-like superfamily L21SP4_RS02615 dc389db316749add4f992e0db3009665 753 PANTHER PTHR24423:SF438 119 747 1.9E-182 T 22-04-2016 L21SP4_RS02615 dc389db316749add4f992e0db3009665 753 Gene3D G3DSA:1.10.287.130 370 439 9.1E-5 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS04780 434fd97b8aeec4a4f5c14d79fd3e1f23 885 Gene3D G3DSA:3.40.50.2300 765 882 5.8E-32 T 22-04-2016 L21SP4_RS04780 434fd97b8aeec4a4f5c14d79fd3e1f23 885 SMART SM00388 509 575 1.5E-11 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS04780 434fd97b8aeec4a4f5c14d79fd3e1f23 885 Pfam PF00072 Response regulator receiver domain 767 877 2.3E-22 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 L21SP4_RS04780 434fd97b8aeec4a4f5c14d79fd3e1f23 885 Pfam PF08447 PAS fold 104 190 1.5E-16 T 22-04-2016 IPR013655 PAS fold-3 GO:0005515 L21SP4_RS04780 434fd97b8aeec4a4f5c14d79fd3e1f23 885 SMART SM00448 764 877 1.6E-29 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 L21SP4_RS04780 434fd97b8aeec4a4f5c14d79fd3e1f23 885 SMART SM00387 616 740 5.2E-29 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS04780 434fd97b8aeec4a4f5c14d79fd3e1f23 885 SMART SM00065 226 380 9.2E-7 T 22-04-2016 IPR003018 GAF domain GO:0005515 L21SP4_RS04780 434fd97b8aeec4a4f5c14d79fd3e1f23 885 SUPERFAMILY SSF55785 386 492 1.22E-30 T 22-04-2016 IPR000014 PAS domain L21SP4_RS04780 434fd97b8aeec4a4f5c14d79fd3e1f23 885 SUPERFAMILY SSF52172 765 882 3.98E-32 T 22-04-2016 IPR011006 CheY-like superfamily L21SP4_RS04780 434fd97b8aeec4a4f5c14d79fd3e1f23 885 Gene3D G3DSA:3.30.450.20 70 193 1.2E-22 T 22-04-2016 L21SP4_RS04780 434fd97b8aeec4a4f5c14d79fd3e1f23 885 Gene3D G3DSA:3.30.450.20 389 492 2.2E-28 T 22-04-2016 L21SP4_RS04780 434fd97b8aeec4a4f5c14d79fd3e1f23 885 SUPERFAMILY SSF55874 565 742 1.83E-36 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS04780 434fd97b8aeec4a4f5c14d79fd3e1f23 885 SUPERFAMILY SSF55781 227 372 2.62E-17 T 22-04-2016 IPR029016 GAF domain-like L21SP4_RS04780 434fd97b8aeec4a4f5c14d79fd3e1f23 885 Pfam PF00989 PAS fold 381 491 1.3E-15 T 22-04-2016 IPR013767 PAS fold GO:0006355 L21SP4_RS04780 434fd97b8aeec4a4f5c14d79fd3e1f23 885 Gene3D G3DSA:3.30.450.40 200 383 3.0E-16 T 22-04-2016 IPR029016 GAF domain-like L21SP4_RS04780 434fd97b8aeec4a4f5c14d79fd3e1f23 885 SMART SM00086 155 197 0.029 T 22-04-2016 IPR001610 PAC motif L21SP4_RS04780 434fd97b8aeec4a4f5c14d79fd3e1f23 885 SMART SM00086 452 494 5.1E-8 T 22-04-2016 IPR001610 PAC motif L21SP4_RS04780 434fd97b8aeec4a4f5c14d79fd3e1f23 885 Gene3D G3DSA:3.30.565.10 579 738 1.7E-35 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS04780 434fd97b8aeec4a4f5c14d79fd3e1f23 885 Gene3D G3DSA:1.10.287.130 502 571 2.5E-8 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS04780 434fd97b8aeec4a4f5c14d79fd3e1f23 885 PANTHER PTHR24423 378 884 1.3E-142 T 22-04-2016 L21SP4_RS04780 434fd97b8aeec4a4f5c14d79fd3e1f23 885 PANTHER PTHR24423 64 212 1.3E-142 T 22-04-2016 L21SP4_RS04780 434fd97b8aeec4a4f5c14d79fd3e1f23 885 Pfam PF01590 GAF domain 227 370 4.4E-7 T 22-04-2016 IPR003018 GAF domain GO:0005515 L21SP4_RS04780 434fd97b8aeec4a4f5c14d79fd3e1f23 885 SUPERFAMILY SSF55785 85 200 3.87E-19 T 22-04-2016 IPR000014 PAS domain L21SP4_RS04780 434fd97b8aeec4a4f5c14d79fd3e1f23 885 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 621 738 9.6E-19 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS04780 434fd97b8aeec4a4f5c14d79fd3e1f23 885 PRINTS PR00344 Bacterial sensor protein C-terminal signature 724 737 3.6E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS04780 434fd97b8aeec4a4f5c14d79fd3e1f23 885 PRINTS PR00344 Bacterial sensor protein C-terminal signature 700 718 3.6E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS04780 434fd97b8aeec4a4f5c14d79fd3e1f23 885 PRINTS PR00344 Bacterial sensor protein C-terminal signature 669 683 3.6E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS04780 434fd97b8aeec4a4f5c14d79fd3e1f23 885 PRINTS PR00344 Bacterial sensor protein C-terminal signature 687 697 3.6E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS04780 434fd97b8aeec4a4f5c14d79fd3e1f23 885 Pfam PF00512 His Kinase A (phospho-acceptor) domain 511 573 4.7E-12 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS04780 434fd97b8aeec4a4f5c14d79fd3e1f23 885 SUPERFAMILY SSF47384 501 573 1.35E-12 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS04780 434fd97b8aeec4a4f5c14d79fd3e1f23 885 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 74 203 9.0E-9 T 22-04-2016 IPR000014 PAS domain L21SP4_RS04780 434fd97b8aeec4a4f5c14d79fd3e1f23 885 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 379 501 3.7E-24 T 22-04-2016 IPR000014 PAS domain L21SP4_RS04780 434fd97b8aeec4a4f5c14d79fd3e1f23 885 SMART SM00091 380 446 1.6E-8 T 22-04-2016 IPR000014 PAS domain L21SP4_RS04780 434fd97b8aeec4a4f5c14d79fd3e1f23 885 SMART SM00091 78 149 3.9E-6 T 22-04-2016 IPR000014 PAS domain L21SP4_RS08905 82d4ddc2634716e1c2b45f9647571bd8 676 SMART SM00292 593 670 1.9E-13 T 22-04-2016 IPR001357 BRCT domain L21SP4_RS08905 82d4ddc2634716e1c2b45f9647571bd8 676 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 333 348 - T 22-04-2016 IPR033136 NAD-dependent DNA ligase, conserved site L21SP4_RS08905 82d4ddc2634716e1c2b45f9647571bd8 676 Gene3D G3DSA:1.10.150.20 505 585 6.4E-30 T 22-04-2016 L21SP4_RS08905 82d4ddc2634716e1c2b45f9647571bd8 676 Gene3D G3DSA:1.10.150.20 436 504 3.8E-28 T 22-04-2016 L21SP4_RS08905 82d4ddc2634716e1c2b45f9647571bd8 676 Gene3D G3DSA:1.10.287.610 6 70 2.2E-28 T 22-04-2016 L21SP4_RS08905 82d4ddc2634716e1c2b45f9647571bd8 676 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 14 662 2.5E-240 T 22-04-2016 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 L21SP4_RS08905 82d4ddc2634716e1c2b45f9647571bd8 676 SUPERFAMILY SSF50249 319 402 3.6E-27 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold L21SP4_RS08905 82d4ddc2634716e1c2b45f9647571bd8 676 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 117 146 - T 22-04-2016 IPR018239 NAD-dependent DNA ligase, active site L21SP4_RS08905 82d4ddc2634716e1c2b45f9647571bd8 676 Pfam PF12826 Helix-hairpin-helix motif 511 574 1.2E-22 T 22-04-2016 L21SP4_RS08905 82d4ddc2634716e1c2b45f9647571bd8 676 SUPERFAMILY SSF47781 419 585 1.19E-49 T 22-04-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 L21SP4_RS08905 82d4ddc2634716e1c2b45f9647571bd8 676 Gene3D G3DSA:3.30.470.30 121 254 6.2E-46 T 22-04-2016 L21SP4_RS08905 82d4ddc2634716e1c2b45f9647571bd8 676 Pfam PF14520 Helix-hairpin-helix domain 449 501 2.0E-4 T 22-04-2016 L21SP4_RS08905 82d4ddc2634716e1c2b45f9647571bd8 676 Hamap MF_01588 DNA ligase [ligA]. 5 667 49.914 T 22-04-2016 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 L21SP4_RS08905 82d4ddc2634716e1c2b45f9647571bd8 676 PIRSF PIRSF001604 1 672 4.9E-238 T 22-04-2016 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 L21SP4_RS08905 82d4ddc2634716e1c2b45f9647571bd8 676 PANTHER PTHR23389:SF9 7 534 7.8E-178 T 22-04-2016 L21SP4_RS08905 82d4ddc2634716e1c2b45f9647571bd8 676 Gene3D G3DSA:3.40.50.10190 592 672 9.2E-24 T 22-04-2016 IPR001357 BRCT domain L21SP4_RS08905 82d4ddc2634716e1c2b45f9647571bd8 676 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 594 665 1.3E-12 T 22-04-2016 IPR001357 BRCT domain L21SP4_RS08905 82d4ddc2634716e1c2b45f9647571bd8 676 SUPERFAMILY SSF56091 5 317 7.4E-113 T 22-04-2016 L21SP4_RS08905 82d4ddc2634716e1c2b45f9647571bd8 676 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 323 400 6.9E-34 T 22-04-2016 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 L21SP4_RS08905 82d4ddc2634716e1c2b45f9647571bd8 676 SUPERFAMILY SSF52113 591 672 7.85E-19 T 22-04-2016 IPR001357 BRCT domain L21SP4_RS08905 82d4ddc2634716e1c2b45f9647571bd8 676 PANTHER PTHR23389 7 534 7.8E-178 T 22-04-2016 L21SP4_RS08905 82d4ddc2634716e1c2b45f9647571bd8 676 Gene3D G3DSA:2.40.50.140 321 392 2.9E-32 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold L21SP4_RS08905 82d4ddc2634716e1c2b45f9647571bd8 676 SMART SM00532 6 449 8.4E-221 T 22-04-2016 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 L21SP4_RS08905 82d4ddc2634716e1c2b45f9647571bd8 676 SMART SM00278 545 564 5.1 T 22-04-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 L21SP4_RS08905 82d4ddc2634716e1c2b45f9647571bd8 676 SMART SM00278 481 500 130.0 T 22-04-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 L21SP4_RS08905 82d4ddc2634716e1c2b45f9647571bd8 676 SMART SM00278 513 532 270.0 T 22-04-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 L21SP4_RS08905 82d4ddc2634716e1c2b45f9647571bd8 676 SMART SM00278 447 466 280.0 T 22-04-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 L21SP4_RS08905 82d4ddc2634716e1c2b45f9647571bd8 676 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 8 320 7.0E-117 T 22-04-2016 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 L21SP4_RS04335 7cce2633f2181d1ed68cf77ff44cac02 371 PANTHER PTHR10657:SF11 50 359 1.3E-60 T 22-04-2016 L21SP4_RS04335 7cce2633f2181d1ed68cf77ff44cac02 371 Pfam PF13616 PPIC-type PPIASE domain 206 310 1.7E-28 T 22-04-2016 L21SP4_RS04335 7cce2633f2181d1ed68cf77ff44cac02 371 PANTHER PTHR10657 50 359 1.3E-60 T 22-04-2016 L21SP4_RS04335 7cce2633f2181d1ed68cf77ff44cac02 371 SUPERFAMILY SSF54534 202 308 5.56E-30 T 22-04-2016 L21SP4_RS04335 7cce2633f2181d1ed68cf77ff44cac02 371 Gene3D G3DSA:3.10.50.40 201 333 1.4E-44 T 22-04-2016 L21SP4_RS04335 7cce2633f2181d1ed68cf77ff44cac02 371 SUPERFAMILY SSF109998 61 238 2.26E-29 T 22-04-2016 IPR027304 Trigger factor/SurA domain L21SP4_RS04335 7cce2633f2181d1ed68cf77ff44cac02 371 Pfam PF13624 SurA N-terminal domain 62 178 8.5E-14 T 22-04-2016 L21SP4_RS07820 b6719bed3d3ed6f951e062e1551d86f2 167 PANTHER PTHR10438:SF281 32 148 2.6E-12 T 22-04-2016 L21SP4_RS07820 b6719bed3d3ed6f951e062e1551d86f2 167 Pfam PF00085 Thioredoxin 50 145 6.1E-15 T 22-04-2016 IPR013766 Thioredoxin domain GO:0045454 L21SP4_RS07820 b6719bed3d3ed6f951e062e1551d86f2 167 SUPERFAMILY SSF52833 39 148 3.32E-22 T 22-04-2016 IPR012336 Thioredoxin-like fold L21SP4_RS07820 b6719bed3d3ed6f951e062e1551d86f2 167 Gene3D G3DSA:3.40.30.10 37 147 1.1E-20 T 22-04-2016 IPR012336 Thioredoxin-like fold L21SP4_RS07820 b6719bed3d3ed6f951e062e1551d86f2 167 PANTHER PTHR10438 32 148 2.6E-12 T 22-04-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 L21SP4_RS06910 7f9067ce60fa81fa72524f2706525c8f 95 Hamap MF_00580 10 kDa chaperonin [groS]. 2 95 25.804 T 22-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 L21SP4_RS06910 7f9067ce60fa81fa72524f2706525c8f 95 PANTHER PTHR10772 1 94 2.6E-46 T 22-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 L21SP4_RS06910 7f9067ce60fa81fa72524f2706525c8f 95 Pfam PF00166 Chaperonin 10 Kd subunit 2 94 8.4E-37 T 22-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 L21SP4_RS06910 7f9067ce60fa81fa72524f2706525c8f 95 SMART SM00883 2 94 4.4E-51 T 22-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 L21SP4_RS06910 7f9067ce60fa81fa72524f2706525c8f 95 Gene3D G3DSA:2.30.33.40 1 94 1.0E-38 T 22-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 L21SP4_RS06910 7f9067ce60fa81fa72524f2706525c8f 95 ProSitePatterns PS00681 Chaperonins cpn10 signature. 3 27 - T 22-04-2016 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 L21SP4_RS06910 7f9067ce60fa81fa72524f2706525c8f 95 PRINTS PR00297 10kDa chaperonin signature 25 46 3.3E-30 T 22-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 L21SP4_RS06910 7f9067ce60fa81fa72524f2706525c8f 95 PRINTS PR00297 10kDa chaperonin signature 60 72 3.3E-30 T 22-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 L21SP4_RS06910 7f9067ce60fa81fa72524f2706525c8f 95 PRINTS PR00297 10kDa chaperonin signature 81 94 3.3E-30 T 22-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 L21SP4_RS06910 7f9067ce60fa81fa72524f2706525c8f 95 PRINTS PR00297 10kDa chaperonin signature 3 18 3.3E-30 T 22-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 L21SP4_RS06910 7f9067ce60fa81fa72524f2706525c8f 95 SUPERFAMILY SSF50129 1 94 7.35E-35 T 22-04-2016 IPR011032 GroES-like L21SP4_RS06690 c10957f851f607bdd532f54ddd721a8a 536 Pfam PF13229 Right handed beta helix region 393 465 4.9E-6 T 22-04-2016 L21SP4_RS06690 c10957f851f607bdd532f54ddd721a8a 536 SMART SM00710 279 301 1200.0 T 22-04-2016 IPR006626 Parallel beta-helix repeat L21SP4_RS06690 c10957f851f607bdd532f54ddd721a8a 536 SMART SM00710 446 478 27.0 T 22-04-2016 IPR006626 Parallel beta-helix repeat L21SP4_RS06690 c10957f851f607bdd532f54ddd721a8a 536 SMART SM00710 392 414 0.25 T 22-04-2016 IPR006626 Parallel beta-helix repeat L21SP4_RS06690 c10957f851f607bdd532f54ddd721a8a 536 Gene3D G3DSA:2.160.20.10 207 302 3.0E-22 T 22-04-2016 IPR012334 Pectin lyase fold L21SP4_RS06690 c10957f851f607bdd532f54ddd721a8a 536 Gene3D G3DSA:2.160.20.10 381 530 3.0E-22 T 22-04-2016 IPR012334 Pectin lyase fold L21SP4_RS06690 c10957f851f607bdd532f54ddd721a8a 536 Gene3D G3DSA:2.160.20.10 8 137 3.0E-22 T 22-04-2016 IPR012334 Pectin lyase fold L21SP4_RS06690 c10957f851f607bdd532f54ddd721a8a 536 SUPERFAMILY SSF51126 7 111 8.39E-32 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor L21SP4_RS06690 c10957f851f607bdd532f54ddd721a8a 536 SUPERFAMILY SSF51126 214 299 8.39E-32 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor L21SP4_RS06690 c10957f851f607bdd532f54ddd721a8a 536 SUPERFAMILY SSF51126 378 529 8.39E-32 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor L21SP4_RS00840 673e9c7a2af51782be8801d5a9e31bbf 292 SUPERFAMILY SSF53850 5 217 1.69E-58 T 22-04-2016 L21SP4_RS00840 673e9c7a2af51782be8801d5a9e31bbf 292 Gene3D G3DSA:3.40.190.10 5 149 1.1E-37 T 22-04-2016 L21SP4_RS00840 673e9c7a2af51782be8801d5a9e31bbf 292 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 6 190 1.4E-52 T 22-04-2016 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17|UniPathway: UPA00031 L21SP4_RS00840 673e9c7a2af51782be8801d5a9e31bbf 292 TIGRFAM TIGR03455 HisG_C-term: ATP phosphoribosyltransferase, C-terminal domain 194 291 3.4E-29 T 22-04-2016 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17|UniPathway: UPA00031 L21SP4_RS00840 673e9c7a2af51782be8801d5a9e31bbf 292 Pfam PF01634 ATP phosphoribosyltransferase 52 208 6.9E-41 T 22-04-2016 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17|UniPathway: UPA00031 L21SP4_RS00840 673e9c7a2af51782be8801d5a9e31bbf 292 Gene3D G3DSA:3.30.70.120 220 291 7.8E-23 T 22-04-2016 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal L21SP4_RS00840 673e9c7a2af51782be8801d5a9e31bbf 292 PANTHER PTHR21403:SF0 1 292 3.8E-82 T 22-04-2016 L21SP4_RS00840 673e9c7a2af51782be8801d5a9e31bbf 292 SUPERFAMILY SSF54913 220 291 1.22E-18 T 22-04-2016 IPR011322 Nitrogen regulatory PII-like, alpha/beta L21SP4_RS00840 673e9c7a2af51782be8801d5a9e31bbf 292 Pfam PF08029 HisG, C-terminal domain 217 289 4.1E-23 T 22-04-2016 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17|UniPathway: UPA00031 L21SP4_RS00840 673e9c7a2af51782be8801d5a9e31bbf 292 Hamap MF_00079 ATP phosphoribosyltransferase [hisG]. 5 292 29.832 T 22-04-2016 IPR020621 ATP phosphoribosyltransferase HisG, long form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17|UniPathway: UPA00031 L21SP4_RS00840 673e9c7a2af51782be8801d5a9e31bbf 292 PANTHER PTHR21403 1 292 3.8E-82 T 22-04-2016 IPR001348 ATP phosphoribosyltransferase HisG GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17|UniPathway: UPA00031 L21SP4_RS00830 c667e761704028dfe9f3b7ea88e2910a 206 PANTHER PTHR33508 1 206 1.2E-12 T 22-04-2016 L21SP4_RS00830 c667e761704028dfe9f3b7ea88e2910a 206 Pfam PF01914 MarC family integral membrane protein 6 200 2.0E-16 T 22-04-2016 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 L21SP4_RS08460 e311fe93371d9c25ce2df61dcd9d405d 182 PRINTS PR00338 Transcription termination factor NUSG signature 158 174 7.8E-19 T 22-04-2016 IPR001062 Transcription antitermination protein, NusG GO:0032784 L21SP4_RS08460 e311fe93371d9c25ce2df61dcd9d405d 182 PRINTS PR00338 Transcription termination factor NUSG signature 57 69 7.8E-19 T 22-04-2016 IPR001062 Transcription antitermination protein, NusG GO:0032784 L21SP4_RS08460 e311fe93371d9c25ce2df61dcd9d405d 182 PRINTS PR00338 Transcription termination factor NUSG signature 140 155 7.8E-19 T 22-04-2016 IPR001062 Transcription antitermination protein, NusG GO:0032784 L21SP4_RS08460 e311fe93371d9c25ce2df61dcd9d405d 182 Gene3D G3DSA:3.30.70.940 2 119 2.3E-39 T 22-04-2016 IPR006645 NusG, N-terminal GO:0006355 L21SP4_RS08460 e311fe93371d9c25ce2df61dcd9d405d 182 SUPERFAMILY SSF50104 126 181 2.56E-18 T 22-04-2016 IPR008991 Translation protein SH3-like domain L21SP4_RS08460 e311fe93371d9c25ce2df61dcd9d405d 182 SMART SM00739 128 155 3.4E-5 T 22-04-2016 IPR005824 KOW L21SP4_RS08460 e311fe93371d9c25ce2df61dcd9d405d 182 PANTHER PTHR30265 1 181 2.8E-67 T 22-04-2016 L21SP4_RS08460 e311fe93371d9c25ce2df61dcd9d405d 182 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 5 181 3.7E-62 T 22-04-2016 IPR001062 Transcription antitermination protein, NusG GO:0032784 L21SP4_RS08460 e311fe93371d9c25ce2df61dcd9d405d 182 Pfam PF00467 KOW motif 132 164 3.2E-7 T 22-04-2016 IPR005824 KOW L21SP4_RS08460 e311fe93371d9c25ce2df61dcd9d405d 182 Gene3D G3DSA:2.30.30.30 121 181 1.5E-27 T 22-04-2016 IPR014722 Ribosomal protein L2 domain 2 L21SP4_RS08460 e311fe93371d9c25ce2df61dcd9d405d 182 SMART SM00738 2 116 5.2E-32 T 22-04-2016 IPR006645 NusG, N-terminal GO:0006355 L21SP4_RS08460 e311fe93371d9c25ce2df61dcd9d405d 182 SUPERFAMILY SSF82679 2 118 2.75E-34 T 22-04-2016 IPR006645 NusG, N-terminal GO:0006355 L21SP4_RS08460 e311fe93371d9c25ce2df61dcd9d405d 182 Pfam PF02357 Transcription termination factor nusG 3 112 2.2E-23 T 22-04-2016 IPR006645 NusG, N-terminal GO:0006355 L21SP4_RS08460 e311fe93371d9c25ce2df61dcd9d405d 182 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 2 182 24.799 T 22-04-2016 IPR001062 Transcription antitermination protein, NusG GO:0032784 L21SP4_RS06480 18bf01e82793c98879706cdf80796cc7 307 SMART SM00244 35 217 8.8E-23 T 22-04-2016 IPR001107 Band 7 domain L21SP4_RS06480 18bf01e82793c98879706cdf80796cc7 307 PANTHER PTHR10264:SF51 23 68 3.7E-73 T 22-04-2016 IPR010201 HflK GO:0016021 L21SP4_RS06480 18bf01e82793c98879706cdf80796cc7 307 SUPERFAMILY SSF117892 103 224 1.09E-18 T 22-04-2016 IPR001107 Band 7 domain L21SP4_RS06480 18bf01e82793c98879706cdf80796cc7 307 PANTHER PTHR10264 23 68 3.7E-73 T 22-04-2016 IPR001972 Stomatin family GO:0016020 L21SP4_RS06480 18bf01e82793c98879706cdf80796cc7 307 Pfam PF01145 SPFH domain / Band 7 family 39 233 2.3E-21 T 22-04-2016 IPR001107 Band 7 domain L21SP4_RS06480 18bf01e82793c98879706cdf80796cc7 307 PANTHER PTHR10264:SF51 91 299 3.7E-73 T 22-04-2016 IPR010201 HflK GO:0016021 L21SP4_RS06480 18bf01e82793c98879706cdf80796cc7 307 PANTHER PTHR10264 91 299 3.7E-73 T 22-04-2016 IPR001972 Stomatin family GO:0016020 L21SP4_RS06480 18bf01e82793c98879706cdf80796cc7 307 TIGRFAM TIGR01933 hflK: HflK protein 37 302 2.7E-79 T 22-04-2016 IPR010201 HflK GO:0016021 L21SP4_RS03770 901ad0e0102ce1585ac875423e7a844f 887 SMART SM01086 786 875 9.6E-33 T 22-04-2016 IPR019489 Clp ATPase, C-terminal L21SP4_RS03770 901ad0e0102ce1585ac875423e7a844f 887 SMART SM00382 203 347 1.9E-11 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS03770 901ad0e0102ce1585ac875423e7a844f 887 SMART SM00382 605 747 4.1E-11 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS03770 901ad0e0102ce1585ac875423e7a844f 887 Gene3D G3DSA:1.10.1780.10 1 153 9.4E-37 T 22-04-2016 IPR004176 Clp, N-terminal GO:0019538 L21SP4_RS03770 901ad0e0102ce1585ac875423e7a844f 887 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 639 657 - T 22-04-2016 IPR028299 ClpA/B, conserved site 2 L21SP4_RS03770 901ad0e0102ce1585ac875423e7a844f 887 Pfam PF07724 AAA domain (Cdc48 subfamily) 604 779 3.8E-54 T 22-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 L21SP4_RS03770 901ad0e0102ce1585ac875423e7a844f 887 PANTHER PTHR11638:SF18 1 876 0.0 T 22-04-2016 L21SP4_RS03770 901ad0e0102ce1585ac875423e7a844f 887 Gene3D G3DSA:3.40.50.300 559 729 2.8E-55 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS03770 901ad0e0102ce1585ac875423e7a844f 887 Gene3D G3DSA:3.40.50.300 767 796 2.8E-55 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS03770 901ad0e0102ce1585ac875423e7a844f 887 PANTHER PTHR11638 1 876 0.0 T 22-04-2016 L21SP4_RS03770 901ad0e0102ce1585ac875423e7a844f 887 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 609 627 1.0E-41 T 22-04-2016 IPR001270 ClpA/B family GO:0005524 L21SP4_RS03770 901ad0e0102ce1585ac875423e7a844f 887 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 716 730 1.0E-41 T 22-04-2016 IPR001270 ClpA/B family GO:0005524 L21SP4_RS03770 901ad0e0102ce1585ac875423e7a844f 887 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 654 672 1.0E-41 T 22-04-2016 IPR001270 ClpA/B family GO:0005524 L21SP4_RS03770 901ad0e0102ce1585ac875423e7a844f 887 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 683 701 1.0E-41 T 22-04-2016 IPR001270 ClpA/B family GO:0005524 L21SP4_RS03770 901ad0e0102ce1585ac875423e7a844f 887 SUPERFAMILY SSF52540 554 870 8.09E-81 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS03770 901ad0e0102ce1585ac875423e7a844f 887 SUPERFAMILY SSF52540 164 553 2.03E-96 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS03770 901ad0e0102ce1585ac875423e7a844f 887 Gene3D G3DSA:3.40.50.300 164 346 1.2E-48 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS03770 901ad0e0102ce1585ac875423e7a844f 887 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 786 864 4.5E-25 T 22-04-2016 IPR019489 Clp ATPase, C-terminal L21SP4_RS03770 901ad0e0102ce1585ac875423e7a844f 887 Gene3D G3DSA:1.10.8.60 797 877 2.3E-29 T 22-04-2016 L21SP4_RS03770 901ad0e0102ce1585ac875423e7a844f 887 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 66 3.0E-10 T 22-04-2016 IPR004176 Clp, N-terminal GO:0019538 L21SP4_RS03770 901ad0e0102ce1585ac875423e7a844f 887 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 97 150 6.8E-11 T 22-04-2016 IPR004176 Clp, N-terminal GO:0019538 L21SP4_RS03770 901ad0e0102ce1585ac875423e7a844f 887 SUPERFAMILY SSF81923 5 161 1.44E-35 T 22-04-2016 IPR004176 Clp, N-terminal GO:0019538 L21SP4_RS03770 901ad0e0102ce1585ac875423e7a844f 887 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 299 311 - T 22-04-2016 IPR018368 ClpA/B, conserved site 1 GO:0005524 L21SP4_RS03770 901ad0e0102ce1585ac875423e7a844f 887 Gene3D G3DSA:1.10.8.60 348 432 4.1E-35 T 22-04-2016 L21SP4_RS03770 901ad0e0102ce1585ac875423e7a844f 887 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 208 328 1.0E-13 T 22-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 L21SP4_RS03770 901ad0e0102ce1585ac875423e7a844f 887 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 7 875 0.0 T 22-04-2016 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0016485 L21SP4_RS01245 73c7cac5ed39210587d8cb7e08402a1a 914 Pfam PF00072 Response regulator receiver domain 795 906 3.9E-17 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 L21SP4_RS01245 73c7cac5ed39210587d8cb7e08402a1a 914 PRINTS PR00344 Bacterial sensor protein C-terminal signature 701 715 1.4E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS01245 73c7cac5ed39210587d8cb7e08402a1a 914 PRINTS PR00344 Bacterial sensor protein C-terminal signature 756 769 1.4E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS01245 73c7cac5ed39210587d8cb7e08402a1a 914 PRINTS PR00344 Bacterial sensor protein C-terminal signature 719 729 1.4E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS01245 73c7cac5ed39210587d8cb7e08402a1a 914 PRINTS PR00344 Bacterial sensor protein C-terminal signature 732 750 1.4E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS01245 73c7cac5ed39210587d8cb7e08402a1a 914 SMART SM00086 236 276 480.0 T 22-04-2016 IPR001610 PAC motif L21SP4_RS01245 73c7cac5ed39210587d8cb7e08402a1a 914 SMART SM00086 363 405 1.4E-11 T 22-04-2016 IPR001610 PAC motif L21SP4_RS01245 73c7cac5ed39210587d8cb7e08402a1a 914 SMART SM00086 485 527 1.1E-6 T 22-04-2016 IPR001610 PAC motif L21SP4_RS01245 73c7cac5ed39210587d8cb7e08402a1a 914 SMART SM00388 542 608 5.4E-6 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS01245 73c7cac5ed39210587d8cb7e08402a1a 914 SMART SM00387 649 772 2.4E-29 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS01245 73c7cac5ed39210587d8cb7e08402a1a 914 PANTHER PTHR24423 82 914 1.1E-162 T 22-04-2016 L21SP4_RS01245 73c7cac5ed39210587d8cb7e08402a1a 914 Pfam PF13185 GAF domain 13 149 1.5E-14 T 22-04-2016 IPR003018 GAF domain GO:0005515 L21SP4_RS01245 73c7cac5ed39210587d8cb7e08402a1a 914 SUPERFAMILY SSF55785 151 274 5.86E-25 T 22-04-2016 IPR000014 PAS domain L21SP4_RS01245 73c7cac5ed39210587d8cb7e08402a1a 914 Pfam PF08448 PAS fold 169 274 8.3E-23 T 22-04-2016 IPR013656 PAS fold-4 L21SP4_RS01245 73c7cac5ed39210587d8cb7e08402a1a 914 SUPERFAMILY SSF52172 793 912 4.7E-25 T 22-04-2016 IPR011006 CheY-like superfamily L21SP4_RS01245 73c7cac5ed39210587d8cb7e08402a1a 914 Gene3D G3DSA:3.30.565.10 583 773 2.2E-40 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS01245 73c7cac5ed39210587d8cb7e08402a1a 914 SUPERFAMILY SSF55781 3 150 3.05E-18 T 22-04-2016 IPR029016 GAF domain-like L21SP4_RS01245 73c7cac5ed39210587d8cb7e08402a1a 914 Gene3D G3DSA:3.30.450.40 4 158 2.5E-26 T 22-04-2016 IPR029016 GAF domain-like L21SP4_RS01245 73c7cac5ed39210587d8cb7e08402a1a 914 SUPERFAMILY SSF55785 298 408 5.58E-22 T 22-04-2016 IPR000014 PAS domain L21SP4_RS01245 73c7cac5ed39210587d8cb7e08402a1a 914 SMART SM00091 163 229 5.5E-10 T 22-04-2016 IPR000014 PAS domain L21SP4_RS01245 73c7cac5ed39210587d8cb7e08402a1a 914 SMART SM00091 413 479 3.6E-8 T 22-04-2016 IPR000014 PAS domain L21SP4_RS01245 73c7cac5ed39210587d8cb7e08402a1a 914 SMART SM00091 288 356 0.015 T 22-04-2016 IPR000014 PAS domain L21SP4_RS01245 73c7cac5ed39210587d8cb7e08402a1a 914 SUPERFAMILY SSF55785 419 525 3.84E-29 T 22-04-2016 IPR000014 PAS domain L21SP4_RS01245 73c7cac5ed39210587d8cb7e08402a1a 914 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 650 770 5.8E-19 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS01245 73c7cac5ed39210587d8cb7e08402a1a 914 Gene3D G3DSA:3.30.450.20 159 265 4.2E-25 T 22-04-2016 L21SP4_RS01245 73c7cac5ed39210587d8cb7e08402a1a 914 SMART SM00065 14 159 2.5E-8 T 22-04-2016 IPR003018 GAF domain GO:0005515 L21SP4_RS01245 73c7cac5ed39210587d8cb7e08402a1a 914 Gene3D G3DSA:3.40.50.2300 792 914 5.5E-27 T 22-04-2016 L21SP4_RS01245 73c7cac5ed39210587d8cb7e08402a1a 914 Pfam PF00512 His Kinase A (phospho-acceptor) domain 544 605 5.1E-7 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS01245 73c7cac5ed39210587d8cb7e08402a1a 914 SUPERFAMILY SSF55874 598 770 1.83E-39 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS01245 73c7cac5ed39210587d8cb7e08402a1a 914 Gene3D G3DSA:3.30.450.20 423 526 1.3E-28 T 22-04-2016 L21SP4_RS01245 73c7cac5ed39210587d8cb7e08402a1a 914 Gene3D G3DSA:3.30.450.20 266 420 3.0E-36 T 22-04-2016 L21SP4_RS01245 73c7cac5ed39210587d8cb7e08402a1a 914 Pfam PF13426 PAS domain 424 526 2.1E-17 T 22-04-2016 IPR000014 PAS domain L21SP4_RS01245 73c7cac5ed39210587d8cb7e08402a1a 914 SUPERFAMILY SSF47384 537 605 4.51E-7 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS01245 73c7cac5ed39210587d8cb7e08402a1a 914 PANTHER PTHR24423:SF544 82 914 1.1E-162 T 22-04-2016 L21SP4_RS01245 73c7cac5ed39210587d8cb7e08402a1a 914 Pfam PF08447 PAS fold 311 399 1.4E-21 T 22-04-2016 IPR013655 PAS fold-3 GO:0005515 L21SP4_RS01245 73c7cac5ed39210587d8cb7e08402a1a 914 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 412 533 2.6E-24 T 22-04-2016 IPR000014 PAS domain L21SP4_RS01245 73c7cac5ed39210587d8cb7e08402a1a 914 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 159 279 5.3E-17 T 22-04-2016 IPR000014 PAS domain L21SP4_RS01245 73c7cac5ed39210587d8cb7e08402a1a 914 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 300 411 7.7E-13 T 22-04-2016 IPR000014 PAS domain L21SP4_RS01245 73c7cac5ed39210587d8cb7e08402a1a 914 SMART SM00448 793 907 8.3E-21 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 L21SP4_RS07985 7c07bc8ec884328fbc3f01c371e3a909 532 Gene3D G3DSA:3.40.30.10 406 464 7.3E-8 T 22-04-2016 IPR012336 Thioredoxin-like fold L21SP4_RS07985 7c07bc8ec884328fbc3f01c371e3a909 532 Pfam PF11412 Disulphide bond corrector protein DsbC 30 123 1.4E-13 T 22-04-2016 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain L21SP4_RS07985 7c07bc8ec884328fbc3f01c371e3a909 532 PANTHER PTHR32234 204 531 1.3E-32 T 22-04-2016 L21SP4_RS07985 7c07bc8ec884328fbc3f01c371e3a909 532 PANTHER PTHR32234:SF0 204 531 1.3E-32 T 22-04-2016 IPR022910 Thiol:disulphide interchange protein DsbD GO:0047134|GO:0055114 L21SP4_RS07985 7c07bc8ec884328fbc3f01c371e3a909 532 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 212 411 3.4E-15 T 22-04-2016 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 L21SP4_RS07985 7c07bc8ec884328fbc3f01c371e3a909 532 SUPERFAMILY SSF74863 35 127 3.79E-11 T 22-04-2016 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain L21SP4_RS07985 7c07bc8ec884328fbc3f01c371e3a909 532 Pfam PF13899 Thioredoxin-like 449 531 2.7E-11 T 22-04-2016 L21SP4_RS07985 7c07bc8ec884328fbc3f01c371e3a909 532 SUPERFAMILY SSF52833 450 532 1.06E-13 T 22-04-2016 IPR012336 Thioredoxin-like fold L21SP4_RS07985 7c07bc8ec884328fbc3f01c371e3a909 532 Gene3D G3DSA:3.40.30.10 465 531 5.7E-19 T 22-04-2016 IPR012336 Thioredoxin-like fold L21SP4_RS07985 7c07bc8ec884328fbc3f01c371e3a909 532 Gene3D G3DSA:2.60.40.1250 33 128 1.6E-14 T 22-04-2016 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain L21SP4_RS04350 96a0d8b56771ee52fea8f3a10aeff72b 262 Gene3D G3DSA:2.160.10.10 4 188 2.6E-46 T 22-04-2016 L21SP4_RS04350 96a0d8b56771ee52fea8f3a10aeff72b 262 PIRSF PIRSF000456 1 261 1.0E-93 T 22-04-2016 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12|UniPathway: UPA00359 L21SP4_RS04350 96a0d8b56771ee52fea8f3a10aeff72b 262 PANTHER PTHR23416:SF8 1 249 1.6E-97 T 22-04-2016 L21SP4_RS04350 96a0d8b56771ee52fea8f3a10aeff72b 262 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 10 38 - T 22-04-2016 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: REACT_17015 L21SP4_RS04350 96a0d8b56771ee52fea8f3a10aeff72b 262 PANTHER PTHR23416 1 249 1.6E-97 T 22-04-2016 L21SP4_RS04350 96a0d8b56771ee52fea8f3a10aeff72b 262 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 36 66 0.002 T 22-04-2016 IPR001451 Hexapeptide repeat L21SP4_RS04350 96a0d8b56771ee52fea8f3a10aeff72b 262 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 104 130 6.3E-6 T 22-04-2016 IPR001451 Hexapeptide repeat L21SP4_RS04350 96a0d8b56771ee52fea8f3a10aeff72b 262 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 4 29 4.2E-4 T 22-04-2016 IPR001451 Hexapeptide repeat L21SP4_RS04350 96a0d8b56771ee52fea8f3a10aeff72b 262 Pfam PF13720 Udp N-acetylglucosamine O-acyltransferase; Domain 2 175 255 1.7E-26 T 22-04-2016 IPR029098 Udp N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12|UniPathway: UPA00359 L21SP4_RS04350 96a0d8b56771ee52fea8f3a10aeff72b 262 Gene3D G3DSA:1.20.1180.10 192 257 2.6E-20 T 22-04-2016 IPR029098 Udp N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12|UniPathway: UPA00359 L21SP4_RS04350 96a0d8b56771ee52fea8f3a10aeff72b 262 SUPERFAMILY SSF51161 4 257 3.68E-68 T 22-04-2016 IPR011004 Trimeric LpxA-like L21SP4_RS04350 96a0d8b56771ee52fea8f3a10aeff72b 262 TIGRFAM TIGR01852 lipid_A_lpxA: acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase 4 255 7.9E-92 T 22-04-2016 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12|UniPathway: UPA00359 L21SP4_RS06425 52e1331b5525d0d40480ef7f02022fb6 494 PANTHER PTHR33678 17 494 1.8E-126 T 22-04-2016 L21SP4_RS06425 52e1331b5525d0d40480ef7f02022fb6 494 Pfam PF13005 zinc-finger binding domain of transposase IS66 116 159 2.1E-7 T 22-04-2016 IPR024474 Zinc-finger binding domain of transposase IS66 L21SP4_RS06425 52e1331b5525d0d40480ef7f02022fb6 494 Pfam PF03050 Transposase IS66 family 175 456 5.2E-60 T 22-04-2016 IPR004291 Transposase, IS66 L21SP4_RS06425 52e1331b5525d0d40480ef7f02022fb6 494 PANTHER PTHR33678:SF2 17 494 1.8E-126 T 22-04-2016 L21SP4_RS09545 4a5cb3371355903fe77b6abe236f33bf 916 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 568 912 8.4E-89 T 22-04-2016 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 L21SP4_RS09545 4a5cb3371355903fe77b6abe236f33bf 916 Gene3D G3DSA:1.20.80.30 118 208 6.6E-32 T 22-04-2016 L21SP4_RS09545 4a5cb3371355903fe77b6abe236f33bf 916 Gene3D G3DSA:3.30.470.20 254 355 3.0E-35 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 L21SP4_RS09545 4a5cb3371355903fe77b6abe236f33bf 916 PIRSF PIRSF000853 2 916 0.0 T 22-04-2016 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 L21SP4_RS09545 4a5cb3371355903fe77b6abe236f33bf 916 SUPERFAMILY SSF56059 3 376 3.18E-126 T 22-04-2016 L21SP4_RS09545 4a5cb3371355903fe77b6abe236f33bf 916 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 804 822 - T 22-04-2016 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 L21SP4_RS09545 4a5cb3371355903fe77b6abe236f33bf 916 PANTHER PTHR22931:SF9 1 916 0.0 T 22-04-2016 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 L21SP4_RS09545 4a5cb3371355903fe77b6abe236f33bf 916 Gene3D G3DSA:3.30.1490.20 16 117 2.7E-54 T 22-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 L21SP4_RS09545 4a5cb3371355903fe77b6abe236f33bf 916 Gene3D G3DSA:3.30.1490.20 210 253 2.7E-54 T 22-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 L21SP4_RS09545 4a5cb3371355903fe77b6abe236f33bf 916 Gene3D G3DSA:3.20.20.60 574 915 2.4E-140 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 L21SP4_RS09545 4a5cb3371355903fe77b6abe236f33bf 916 SUPERFAMILY SSF52009 409 538 1.7E-34 T 22-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 L21SP4_RS09545 4a5cb3371355903fe77b6abe236f33bf 916 Gene3D G3DSA:3.50.30.10 425 532 2.4E-38 T 22-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 L21SP4_RS09545 4a5cb3371355903fe77b6abe236f33bf 916 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 313 360 4.3E-11 T 22-04-2016 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 L21SP4_RS09545 4a5cb3371355903fe77b6abe236f33bf 916 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 24 302 4.6E-41 T 22-04-2016 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 L21SP4_RS09545 4a5cb3371355903fe77b6abe236f33bf 916 TIGRFAM TIGR01828 pyru_phos_dikin: pyruvate, phosphate dikinase 3 914 0.0 T 22-04-2016 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 L21SP4_RS09545 4a5cb3371355903fe77b6abe236f33bf 916 Pfam PF00391 PEP-utilising enzyme, mobile domain 448 529 4.5E-24 T 22-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 L21SP4_RS09545 4a5cb3371355903fe77b6abe236f33bf 916 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 476 487 - T 22-04-2016 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 L21SP4_RS09545 4a5cb3371355903fe77b6abe236f33bf 916 PANTHER PTHR22931 1 916 0.0 T 22-04-2016 L21SP4_RS09545 4a5cb3371355903fe77b6abe236f33bf 916 Gene3D G3DSA:1.10.189.10 380 424 1.9E-14 T 22-04-2016 L21SP4_RS09545 4a5cb3371355903fe77b6abe236f33bf 916 SUPERFAMILY SSF51621 565 915 8.48E-124 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 L21SP4_RS05675 b649368b603d46e2a36671665a9eb79c 563 Pfam PF01895 PhoU domain 362 448 1.4E-5 T 22-04-2016 IPR026022 PhoU domain L21SP4_RS05675 b649368b603d46e2a36671665a9eb79c 563 SUPERFAMILY SSF109755 348 558 6.7E-19 T 22-04-2016 L21SP4_RS05675 b649368b603d46e2a36671665a9eb79c 563 TIGRFAM TIGR00704 NaPi_cotrn_rel: Na/Pi-cotransporter II-related protein 5 326 1.8E-75 T 22-04-2016 IPR004633 Na/Pi-cotransporter II-related/YqeW-like protein GO:0016020 L21SP4_RS05675 b649368b603d46e2a36671665a9eb79c 563 PANTHER PTHR10010 1 462 2.4E-99 T 22-04-2016 L21SP4_RS05675 b649368b603d46e2a36671665a9eb79c 563 Pfam PF02690 Na+/Pi-cotransporter 16 155 2.5E-49 T 22-04-2016 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: REACT_15518 L21SP4_RS05675 b649368b603d46e2a36671665a9eb79c 563 Pfam PF02690 Na+/Pi-cotransporter 182 267 1.7E-15 T 22-04-2016 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: REACT_15518 L21SP4_RS05675 b649368b603d46e2a36671665a9eb79c 563 Gene3D G3DSA:1.20.58.220 345 451 1.0E-8 T 22-04-2016 L21SP4_RS05675 b649368b603d46e2a36671665a9eb79c 563 PANTHER PTHR10010:SF26 1 462 2.4E-99 T 22-04-2016 L21SP4_RS07180 9d534b7bd6d45a3e3dce70423f36492c 640 PANTHER PTHR11482 442 600 2.8E-215 T 22-04-2016 L21SP4_RS07180 9d534b7bd6d45a3e3dce70423f36492c 640 PANTHER PTHR11482 9 370 2.8E-215 T 22-04-2016 L21SP4_RS07180 9d534b7bd6d45a3e3dce70423f36492c 640 PANTHER PTHR11482:SF36 442 600 2.8E-215 T 22-04-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 L21SP4_RS07180 9d534b7bd6d45a3e3dce70423f36492c 640 PANTHER PTHR11482:SF36 9 370 2.8E-215 T 22-04-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 L21SP4_RS07180 9d534b7bd6d45a3e3dce70423f36492c 640 SUPERFAMILY SSF51419 74 352 5.61E-61 T 22-04-2016 IPR029066 PLP-binding barrel L21SP4_RS07180 9d534b7bd6d45a3e3dce70423f36492c 640 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 87 350 4.9E-39 T 22-04-2016 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 Reactome: REACT_13 L21SP4_RS07180 9d534b7bd6d45a3e3dce70423f36492c 640 Gene3D G3DSA:3.20.20.10 75 336 7.6E-52 T 22-04-2016 IPR029066 PLP-binding barrel L21SP4_RS07180 9d534b7bd6d45a3e3dce70423f36492c 640 Hamap MF_01417 Biosynthetic arginine decarboxylase [speA]. 9 640 40.312 T 22-04-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 L21SP4_RS07180 9d534b7bd6d45a3e3dce70423f36492c 640 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 105 123 - T 22-04-2016 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site Reactome: REACT_13 L21SP4_RS07180 9d534b7bd6d45a3e3dce70423f36492c 640 TIGRFAM TIGR01273 speA: arginine decarboxylase 12 638 1.1E-218 T 22-04-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 L21SP4_RS07180 9d534b7bd6d45a3e3dce70423f36492c 640 SUPERFAMILY SSF50621 445 578 1.78E-6 T 22-04-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 L21SP4_RS07180 9d534b7bd6d45a3e3dce70423f36492c 640 PIRSF PIRSF001336 1 640 1.8E-249 T 22-04-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 L21SP4_RS07180 9d534b7bd6d45a3e3dce70423f36492c 640 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 340 359 3.1E-16 T 22-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 L21SP4_RS07180 9d534b7bd6d45a3e3dce70423f36492c 640 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 105 123 3.1E-16 T 22-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 L21SP4_RS07180 9d534b7bd6d45a3e3dce70423f36492c 640 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 545 558 3.1E-16 T 22-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 L21SP4_RS07180 9d534b7bd6d45a3e3dce70423f36492c 640 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 129 141 3.1E-16 T 22-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 L21SP4_RS07180 9d534b7bd6d45a3e3dce70423f36492c 640 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 246 259 3.1E-16 T 22-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 L21SP4_RS07180 9d534b7bd6d45a3e3dce70423f36492c 640 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 430 564 8.2E-25 T 22-04-2016 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 Reactome: REACT_13 L21SP4_RS07180 9d534b7bd6d45a3e3dce70423f36492c 640 PRINTS PR01180 Arginine decarboxylase signature 545 566 3.5E-62 T 22-04-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 L21SP4_RS07180 9d534b7bd6d45a3e3dce70423f36492c 640 PRINTS PR01180 Arginine decarboxylase signature 97 111 3.5E-62 T 22-04-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 L21SP4_RS07180 9d534b7bd6d45a3e3dce70423f36492c 640 PRINTS PR01180 Arginine decarboxylase signature 179 200 3.5E-62 T 22-04-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 L21SP4_RS07180 9d534b7bd6d45a3e3dce70423f36492c 640 PRINTS PR01180 Arginine decarboxylase signature 467 488 3.5E-62 T 22-04-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 L21SP4_RS07180 9d534b7bd6d45a3e3dce70423f36492c 640 PRINTS PR01180 Arginine decarboxylase signature 492 517 3.5E-62 T 22-04-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 L21SP4_RS07180 9d534b7bd6d45a3e3dce70423f36492c 640 PRINTS PR01180 Arginine decarboxylase signature 73 88 3.5E-62 T 22-04-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 L21SP4_RS07180 9d534b7bd6d45a3e3dce70423f36492c 640 PRINTS PR01180 Arginine decarboxylase signature 153 168 3.5E-62 T 22-04-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 L21SP4_RS07180 9d534b7bd6d45a3e3dce70423f36492c 640 PRINTS PR01180 Arginine decarboxylase signature 330 347 3.5E-62 T 22-04-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 L21SP4_RS07180 9d534b7bd6d45a3e3dce70423f36492c 640 PRINTS PR01180 Arginine decarboxylase signature 203 225 3.5E-62 T 22-04-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 L21SP4_RS07180 9d534b7bd6d45a3e3dce70423f36492c 640 Gene3D G3DSA:2.40.37.10 337 363 3.4E-12 T 22-04-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 L21SP4_RS07180 9d534b7bd6d45a3e3dce70423f36492c 640 Gene3D G3DSA:2.40.37.10 458 579 3.4E-12 T 22-04-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 L21SP4_RS03240 92bf19f05a1c72488b13cb98cb0662cb 431 SUPERFAMILY SSF116734 231 420 3.43E-37 T 22-04-2016 L21SP4_RS03240 92bf19f05a1c72488b13cb98cb0662cb 431 PANTHER PTHR30408 36 289 7.5E-29 T 22-04-2016 L21SP4_RS03240 92bf19f05a1c72488b13cb98cb0662cb 431 SUPERFAMILY SSF116734 33 239 6.05E-45 T 22-04-2016 L21SP4_RS03240 92bf19f05a1c72488b13cb98cb0662cb 431 PANTHER PTHR30408:SF2 36 289 7.5E-29 T 22-04-2016 L21SP4_RS03240 92bf19f05a1c72488b13cb98cb0662cb 431 Pfam PF01420 Type I restriction modification DNA specificity domain 45 213 1.3E-19 T 22-04-2016 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 L21SP4_RS03240 92bf19f05a1c72488b13cb98cb0662cb 431 Pfam PF01420 Type I restriction modification DNA specificity domain 241 396 1.3E-19 T 22-04-2016 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 L21SP4_RS03965 de2509b0316c2b5460865e138d66ef89 153 SUPERFAMILY SSF51230 76 151 1.7E-21 T 22-04-2016 IPR011053 Single hybrid motif L21SP4_RS03965 de2509b0316c2b5460865e138d66ef89 153 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 97 111 1.0E-16 T 22-04-2016 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 UniPathway: UPA00094 L21SP4_RS03965 de2509b0316c2b5460865e138d66ef89 153 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 112 125 1.0E-16 T 22-04-2016 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 UniPathway: UPA00094 L21SP4_RS03965 de2509b0316c2b5460865e138d66ef89 153 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 80 93 1.0E-16 T 22-04-2016 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 UniPathway: UPA00094 L21SP4_RS03965 de2509b0316c2b5460865e138d66ef89 153 PANTHER PTHR23151:SF64 1 151 3.7E-42 T 22-04-2016 L21SP4_RS03965 de2509b0316c2b5460865e138d66ef89 153 Pfam PF00364 Biotin-requiring enzyme 77 148 2.8E-21 T 22-04-2016 IPR000089 Biotin/lipoyl attachment L21SP4_RS03965 de2509b0316c2b5460865e138d66ef89 153 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 1 151 3.5E-47 T 22-04-2016 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 UniPathway: UPA00094 L21SP4_RS03965 de2509b0316c2b5460865e138d66ef89 153 Gene3D G3DSA:2.40.50.100 75 151 6.4E-27 T 22-04-2016 L21SP4_RS03965 de2509b0316c2b5460865e138d66ef89 153 PANTHER PTHR23151 1 151 3.7E-42 T 22-04-2016 L21SP4_RS07790 987d1ded19e61328e75ab6f6c79c8c58 485 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 5 88 4.1E-13 T 22-04-2016 IPR007831 General secretory system II, protein E, N-terminal GO:0005524|GO:0006810 L21SP4_RS07790 987d1ded19e61328e75ab6f6c79c8c58 485 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 299 313 - T 22-04-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 L21SP4_RS07790 987d1ded19e61328e75ab6f6c79c8c58 485 PANTHER PTHR30258 13 478 1.3E-132 T 22-04-2016 L21SP4_RS07790 987d1ded19e61328e75ab6f6c79c8c58 485 Pfam PF00437 Type II/IV secretion system protein 109 371 3.1E-66 T 22-04-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 L21SP4_RS07790 987d1ded19e61328e75ab6f6c79c8c58 485 Gene3D G3DSA:3.40.50.300 209 478 5.8E-84 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS07790 987d1ded19e61328e75ab6f6c79c8c58 485 SUPERFAMILY SSF160246 3 85 2.09E-13 T 22-04-2016 L21SP4_RS07790 987d1ded19e61328e75ab6f6c79c8c58 485 SMART SM00382 232 361 2.0E-6 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS07790 987d1ded19e61328e75ab6f6c79c8c58 485 PANTHER PTHR30258:SF2 13 478 1.3E-132 T 22-04-2016 L21SP4_RS07790 987d1ded19e61328e75ab6f6c79c8c58 485 Gene3D G3DSA:3.30.450.90 91 200 1.2E-32 T 22-04-2016 L21SP4_RS07790 987d1ded19e61328e75ab6f6c79c8c58 485 SUPERFAMILY SSF52540 94 478 1.15E-75 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS03650 a09a5a67e589b0e2faa176386cba7add 659 PANTHER PTHR23083 537 634 7.9E-12 T 22-04-2016 L21SP4_RS03650 a09a5a67e589b0e2faa176386cba7add 659 Pfam PF14559 Tetratricopeptide repeat 552 614 4.4E-8 T 22-04-2016 L21SP4_RS03650 a09a5a67e589b0e2faa176386cba7add 659 SMART SM00028 574 607 8.9E-4 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS03650 a09a5a67e589b0e2faa176386cba7add 659 SMART SM00028 608 641 320.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS03650 a09a5a67e589b0e2faa176386cba7add 659 Gene3D G3DSA:1.25.40.10 537 636 1.6E-18 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS03650 a09a5a67e589b0e2faa176386cba7add 659 SUPERFAMILY SSF48452 534 640 2.61E-17 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS01160 14dd3ae262561bfac76fb42ac8a2a8a2 333 Pfam PF02504 Fatty acid synthesis protein 1 321 1.3E-106 T 22-04-2016 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 UniPathway: UPA00085 L21SP4_RS01160 14dd3ae262561bfac76fb42ac8a2a8a2 333 PANTHER PTHR30100:SF1 1 329 5.4E-125 T 22-04-2016 L21SP4_RS01160 14dd3ae262561bfac76fb42ac8a2a8a2 333 PANTHER PTHR30100 1 329 5.4E-125 T 22-04-2016 L21SP4_RS01160 14dd3ae262561bfac76fb42ac8a2a8a2 333 TIGRFAM TIGR00182 plsX: fatty acid/phospholipid synthesis protein PlsX 1 330 1.5E-112 T 22-04-2016 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 UniPathway: UPA00085 L21SP4_RS01160 14dd3ae262561bfac76fb42ac8a2a8a2 333 SUPERFAMILY SSF53659 1 328 5.35E-94 T 22-04-2016 L21SP4_RS01160 14dd3ae262561bfac76fb42ac8a2a8a2 333 PIRSF PIRSF002465 1 333 9.4E-119 T 22-04-2016 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 UniPathway: UPA00085 L21SP4_RS01160 14dd3ae262561bfac76fb42ac8a2a8a2 333 Hamap MF_00019 Phosphate acyltransferase [plsX]. 1 333 138.806 T 22-04-2016 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 UniPathway: UPA00085 L21SP4_RS01160 14dd3ae262561bfac76fb42ac8a2a8a2 333 Gene3D G3DSA:3.40.718.10 1 330 4.4E-127 T 22-04-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 L21SP4_RS03955 5989cec1a5fcf2bb4fd22ef6ffca3b21 430 PANTHER PTHR23526:SF2 6 301 1.5E-14 T 22-04-2016 L21SP4_RS03955 5989cec1a5fcf2bb4fd22ef6ffca3b21 430 PANTHER PTHR23526 6 301 1.5E-14 T 22-04-2016 L21SP4_RS03955 5989cec1a5fcf2bb4fd22ef6ffca3b21 430 SUPERFAMILY SSF103473 12 412 1.44E-32 T 22-04-2016 IPR020846 Major facilitator superfamily domain L21SP4_RS03955 5989cec1a5fcf2bb4fd22ef6ffca3b21 430 Pfam PF07690 Major Facilitator Superfamily 35 362 5.3E-18 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 L21SP4_RS03955 5989cec1a5fcf2bb4fd22ef6ffca3b21 430 Gene3D G3DSA:1.20.1250.20 220 412 2.9E-10 T 22-04-2016 L21SP4_RS03955 5989cec1a5fcf2bb4fd22ef6ffca3b21 430 Gene3D G3DSA:1.20.1250.20 15 195 3.7E-14 T 22-04-2016 L21SP4_RS00440 c165b158d95fec4e4e8bef9b0aaaaa16 389 PANTHER PTHR11360 1 387 3.8E-61 T 22-04-2016 L21SP4_RS00440 c165b158d95fec4e4e8bef9b0aaaaa16 389 PANTHER PTHR11360:SF3 1 387 3.8E-61 T 22-04-2016 L21SP4_RS00440 c165b158d95fec4e4e8bef9b0aaaaa16 389 Pfam PF07690 Major Facilitator Superfamily 22 221 2.4E-16 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 L21SP4_RS00440 c165b158d95fec4e4e8bef9b0aaaaa16 389 Gene3D G3DSA:1.20.1250.20 202 379 1.6E-15 T 22-04-2016 L21SP4_RS00440 c165b158d95fec4e4e8bef9b0aaaaa16 389 SUPERFAMILY SSF103473 5 383 4.58E-44 T 22-04-2016 IPR020846 Major facilitator superfamily domain L21SP4_RS00440 c165b158d95fec4e4e8bef9b0aaaaa16 389 Gene3D G3DSA:1.20.1250.20 5 182 9.8E-18 T 22-04-2016 L21SP4_RS00090 73508f51471f8e06afb214c5ad3a8c05 558 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 463 474 - T 22-04-2016 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 L21SP4_RS00090 73508f51471f8e06afb214c5ad3a8c05 558 SUPERFAMILY SSF52016 375 555 2.59E-62 T 22-04-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel L21SP4_RS00090 73508f51471f8e06afb214c5ad3a8c05 558 PANTHER PTHR21000:SF11 1 555 0.0 T 22-04-2016 L21SP4_RS00090 73508f51471f8e06afb214c5ad3a8c05 558 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 14 555 8.6E-240 T 22-04-2016 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 L21SP4_RS00090 73508f51471f8e06afb214c5ad3a8c05 558 Pfam PF00920 Dehydratase family 31 552 1.0E-218 T 22-04-2016 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 L21SP4_RS00090 73508f51471f8e06afb214c5ad3a8c05 558 PANTHER PTHR21000 1 555 0.0 T 22-04-2016 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 L21SP4_RS00090 73508f51471f8e06afb214c5ad3a8c05 558 SUPERFAMILY SSF143975 2 374 3.14E-132 T 22-04-2016 L21SP4_RS00090 73508f51471f8e06afb214c5ad3a8c05 558 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 119 129 - T 22-04-2016 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 L21SP4_RS00090 73508f51471f8e06afb214c5ad3a8c05 558 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 1 555 46.074 T 22-04-2016 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 L21SP4_RS10840 e26f5d211b54c55d9e7670e614ba55c6 240 PANTHER PTHR32552 23 226 4.6E-26 T 22-04-2016 L21SP4_RS10840 e26f5d211b54c55d9e7670e614ba55c6 240 Pfam PF00665 Integrase core domain 72 184 4.9E-21 T 22-04-2016 IPR001584 Integrase, catalytic core GO:0015074 L21SP4_RS10840 e26f5d211b54c55d9e7670e614ba55c6 240 Pfam PF13276 HTH-like domain 3 50 1.1E-6 T 22-04-2016 IPR025948 HTH-like domain L21SP4_RS10840 e26f5d211b54c55d9e7670e614ba55c6 240 SUPERFAMILY SSF53098 72 236 1.64E-46 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS10840 e26f5d211b54c55d9e7670e614ba55c6 240 Gene3D G3DSA:3.30.420.10 69 224 3.8E-32 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS10855 600d05090358400265a4b4a96e45728b 476 Gene3D G3DSA:3.40.50.720 276 357 1.7E-10 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS10855 600d05090358400265a4b4a96e45728b 476 Gene3D G3DSA:3.40.50.1480 12 151 2.0E-121 T 22-04-2016 L21SP4_RS10855 600d05090358400265a4b4a96e45728b 476 Gene3D G3DSA:3.40.50.1480 188 275 2.0E-121 T 22-04-2016 L21SP4_RS10855 600d05090358400265a4b4a96e45728b 476 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 11 468 48.731 T 22-04-2016 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 L21SP4_RS10855 600d05090358400265a4b4a96e45728b 476 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 237 396 4.1E-81 T 22-04-2016 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 L21SP4_RS10855 600d05090358400265a4b4a96e45728b 476 SUPERFAMILY SSF52283 189 236 2.15E-113 T 22-04-2016 L21SP4_RS10855 600d05090358400265a4b4a96e45728b 476 SUPERFAMILY SSF52283 397 476 2.15E-113 T 22-04-2016 L21SP4_RS10855 600d05090358400265a4b4a96e45728b 476 SUPERFAMILY SSF52283 14 152 2.15E-113 T 22-04-2016 L21SP4_RS10855 600d05090358400265a4b4a96e45728b 476 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 15 475 9.1E-143 T 22-04-2016 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 L21SP4_RS10855 600d05090358400265a4b4a96e45728b 476 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 16 468 2.1E-184 T 22-04-2016 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 L21SP4_RS10855 600d05090358400265a4b4a96e45728b 476 PANTHER PTHR23420 187 476 0.0 T 22-04-2016 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 L21SP4_RS10855 600d05090358400265a4b4a96e45728b 476 PANTHER PTHR23420 9 150 0.0 T 22-04-2016 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 L21SP4_RS10855 600d05090358400265a4b4a96e45728b 476 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 87 101 - T 22-04-2016 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 L21SP4_RS10855 600d05090358400265a4b4a96e45728b 476 SMART SM00997 237 396 1.1E-113 T 22-04-2016 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 L21SP4_RS10855 600d05090358400265a4b4a96e45728b 476 SMART SM00996 15 475 0.0 T 22-04-2016 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 L21SP4_RS10855 600d05090358400265a4b4a96e45728b 476 PIRSF PIRSF001109 2 476 3.3E-190 T 22-04-2016 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 L21SP4_RS10855 600d05090358400265a4b4a96e45728b 476 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 259 275 - T 22-04-2016 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 L21SP4_RS10855 600d05090358400265a4b4a96e45728b 476 Gene3D G3DSA:3.40.50.1480 366 476 1.9E-32 T 22-04-2016 L21SP4_RS10855 600d05090358400265a4b4a96e45728b 476 SUPERFAMILY SSF51735 237 396 8.63E-77 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS04415 d1d46ef38b1660bc7835926177b03daa 664 SUPERFAMILY SSF49899 486 660 8.04E-8 T 22-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP4_RS04415 d1d46ef38b1660bc7835926177b03daa 664 SUPERFAMILY SSF53649 1 442 4.28E-98 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS04415 d1d46ef38b1660bc7835926177b03daa 664 Gene3D G3DSA:3.40.720.10 2 371 3.5E-81 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS04415 d1d46ef38b1660bc7835926177b03daa 664 PANTHER PTHR10342:SF207 1 466 1.8E-105 T 22-04-2016 L21SP4_RS04415 d1d46ef38b1660bc7835926177b03daa 664 Gene3D G3DSA:3.30.1120.10 379 456 3.1E-15 T 22-04-2016 L21SP4_RS04415 d1d46ef38b1660bc7835926177b03daa 664 Pfam PF00884 Sulfatase 2 350 3.4E-50 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS04415 d1d46ef38b1660bc7835926177b03daa 664 PANTHER PTHR10342 1 466 1.8E-105 T 22-04-2016 L21SP4_RS00930 ba76fa82fd67bdd2f75ea24005b006a1 1255 Pfam PF01841 Transglutaminase-like superfamily 285 389 1.4E-10 T 22-04-2016 IPR002931 Transglutaminase-like L21SP4_RS00930 ba76fa82fd67bdd2f75ea24005b006a1 1255 SUPERFAMILY SSF54001 886 968 8.01E-7 T 22-04-2016 L21SP4_RS00930 ba76fa82fd67bdd2f75ea24005b006a1 1255 SUPERFAMILY SSF54001 1001 1078 8.01E-7 T 22-04-2016 L21SP4_RS00930 ba76fa82fd67bdd2f75ea24005b006a1 1255 SMART SM00460 332 399 0.0028 T 22-04-2016 IPR002931 Transglutaminase-like L21SP4_RS00930 ba76fa82fd67bdd2f75ea24005b006a1 1255 Pfam PF12969 Domain of Unknown Function with PDB structure (DUF3857) 63 234 3.7E-21 T 22-04-2016 IPR024618 Domain of unknown function DUF3857 L21SP4_RS00930 ba76fa82fd67bdd2f75ea24005b006a1 1255 Pfam PF12969 Domain of Unknown Function with PDB structure (DUF3857) 679 839 1.7E-23 T 22-04-2016 IPR024618 Domain of unknown function DUF3857 L21SP4_RS00930 ba76fa82fd67bdd2f75ea24005b006a1 1255 SUPERFAMILY SSF54001 272 416 6.48E-15 T 22-04-2016 L21SP4_RS04790 e12a554842ba0bb5cd8a46d8c45f8cd8 382 PANTHER PTHR32268:SF11 17 380 9.3E-112 T 22-04-2016 L21SP4_RS04790 e12a554842ba0bb5cd8a46d8c45f8cd8 382 SUPERFAMILY SSF53474 18 380 3.34E-82 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold L21SP4_RS04790 e12a554842ba0bb5cd8a46d8c45f8cd8 382 TIGRFAM TIGR01392 homoserO_Ac_trn: homoserine O-acetyltransferase 18 379 3.4E-105 T 22-04-2016 IPR008220 Homoserine acetyltransferase GO:0004414|GO:0005737|GO:0009086 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344|UniPathway: UPA00051 L21SP4_RS04790 e12a554842ba0bb5cd8a46d8c45f8cd8 382 Gene3D G3DSA:3.40.50.1820 29 380 3.0E-28 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold L21SP4_RS04790 e12a554842ba0bb5cd8a46d8c45f8cd8 382 Pfam PF00561 alpha/beta hydrolase fold 46 368 2.0E-23 T 22-04-2016 IPR000073 Alpha/beta hydrolase fold-1 L21SP4_RS04790 e12a554842ba0bb5cd8a46d8c45f8cd8 382 PANTHER PTHR32268 17 380 9.3E-112 T 22-04-2016 L21SP4_RS04790 e12a554842ba0bb5cd8a46d8c45f8cd8 382 PIRSF PIRSF000443 13 382 7.7E-100 T 22-04-2016 IPR008220 Homoserine acetyltransferase GO:0004414|GO:0005737|GO:0009086 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344|UniPathway: UPA00051 L21SP4_RS08990 32f885576eaa74d30eac4effdb211660 316 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 13 292 1.3E-35 T 22-04-2016 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD L21SP4_RS08990 32f885576eaa74d30eac4effdb211660 316 PANTHER PTHR40277 1 300 5.0E-33 T 22-04-2016 L21SP4_RS09495 c69329715390229cc1cbc714976c3a95 123 SUPERFAMILY SSF81301 13 117 9.81E-33 T 22-04-2016 L21SP4_RS09495 c69329715390229cc1cbc714976c3a95 123 PANTHER PTHR21043 15 116 1.5E-31 T 22-04-2016 IPR004394 Protein Iojap/ribosomal silencing factor RsfS L21SP4_RS09495 c69329715390229cc1cbc714976c3a95 123 Pfam PF02410 Ribosomal silencing factor during starvation 15 110 7.6E-25 T 22-04-2016 L21SP4_RS09495 c69329715390229cc1cbc714976c3a95 123 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 15 110 4.1E-30 T 22-04-2016 IPR004394 Protein Iojap/ribosomal silencing factor RsfS L21SP4_RS09495 c69329715390229cc1cbc714976c3a95 123 Gene3D G3DSA:3.30.460.10 14 114 2.9E-31 T 22-04-2016 L21SP4_RS09495 c69329715390229cc1cbc714976c3a95 123 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 5 111 21.611 T 22-04-2016 IPR004394 Protein Iojap/ribosomal silencing factor RsfS L21SP4_RS01955 e9c1b513a2756befd873893bc3ebaede 604 PANTHER PTHR33307 28 159 5.9E-128 T 22-04-2016 L21SP4_RS01955 e9c1b513a2756befd873893bc3ebaede 604 PANTHER PTHR33307 212 585 5.9E-128 T 22-04-2016 L21SP4_RS01955 e9c1b513a2756befd873893bc3ebaede 604 Pfam PF05592 Bacterial alpha-L-rhamnosidase 414 586 6.6E-31 T 22-04-2016 IPR008902 Bacterial alpha-L-rhamnosidase L21SP4_RS01955 e9c1b513a2756befd873893bc3ebaede 604 PANTHER PTHR33307:SF5 28 159 5.9E-128 T 22-04-2016 L21SP4_RS01955 e9c1b513a2756befd873893bc3ebaede 604 PANTHER PTHR33307:SF5 212 585 5.9E-128 T 22-04-2016 L21SP4_RS01955 e9c1b513a2756befd873893bc3ebaede 604 Pfam PF08531 Alpha-L-rhamnosidase N-terminal domain 234 404 7.0E-50 T 22-04-2016 IPR013737 Bacterial alpha-L-rhamnosidase N-terminal L21SP4_RS01955 e9c1b513a2756befd873893bc3ebaede 604 Gene3D G3DSA:2.60.120.260 404 498 1.6E-9 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS03925 fb45f59c872a20b6d84612e18e82373e 332 Gene3D G3DSA:3.20.10.10 157 317 8.9E-30 T 22-04-2016 L21SP4_RS03925 fb45f59c872a20b6d84612e18e82373e 332 Gene3D G3DSA:3.30.470.10 38 146 6.0E-30 T 22-04-2016 L21SP4_RS03925 fb45f59c872a20b6d84612e18e82373e 332 PANTHER PTHR11825:SF48 30 328 6.6E-75 T 22-04-2016 L21SP4_RS03925 fb45f59c872a20b6d84612e18e82373e 332 SUPERFAMILY SSF56752 46 317 4.71E-60 T 22-04-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 L21SP4_RS03925 fb45f59c872a20b6d84612e18e82373e 332 Pfam PF01063 Amino-transferase class IV 60 289 2.7E-42 T 22-04-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 L21SP4_RS03925 fb45f59c872a20b6d84612e18e82373e 332 PANTHER PTHR11825 30 328 6.6E-75 T 22-04-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 L21SP4_RS09895 e2ad64aa1bdbb7bdc6c5944e9224a90b 374 PANTHER PTHR13847:SF209 7 326 9.8E-52 T 22-04-2016 L21SP4_RS09895 e2ad64aa1bdbb7bdc6c5944e9224a90b 374 Gene3D G3DSA:2.40.30.110 277 363 2.3E-20 T 22-04-2016 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 L21SP4_RS09895 e2ad64aa1bdbb7bdc6c5944e9224a90b 374 PANTHER PTHR13847 7 326 9.8E-52 T 22-04-2016 L21SP4_RS09895 e2ad64aa1bdbb7bdc6c5944e9224a90b 374 PIRSF PIRSF006487 2 367 2.9E-80 T 22-04-2016 IPR028896 Aminomethyltransferase/Dimethylsulfonioproprionate demethylase DmdA KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 L21SP4_RS09895 e2ad64aa1bdbb7bdc6c5944e9224a90b 374 Gene3D G3DSA:3.30.1360.120 148 235 1.5E-43 T 22-04-2016 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 L21SP4_RS09895 e2ad64aa1bdbb7bdc6c5944e9224a90b 374 Gene3D G3DSA:3.30.1360.120 8 58 1.5E-43 T 22-04-2016 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 L21SP4_RS09895 e2ad64aa1bdbb7bdc6c5944e9224a90b 374 SUPERFAMILY SSF101790 272 363 1.24E-18 T 22-04-2016 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain L21SP4_RS09895 e2ad64aa1bdbb7bdc6c5944e9224a90b 374 SUPERFAMILY SSF103025 5 273 3.45E-85 T 22-04-2016 L21SP4_RS09895 e2ad64aa1bdbb7bdc6c5944e9224a90b 374 Pfam PF01571 Aminomethyltransferase folate-binding domain 12 257 2.0E-79 T 22-04-2016 IPR006222 Glycine cleavage T-protein-like, N-terminal L21SP4_RS09895 e2ad64aa1bdbb7bdc6c5944e9224a90b 374 Gene3D G3DSA:3.30.70.1400 59 145 2.8E-29 T 22-04-2016 L21SP4_RS09895 e2ad64aa1bdbb7bdc6c5944e9224a90b 374 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 264 350 5.8E-15 T 22-04-2016 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 L21SP4_RS09895 e2ad64aa1bdbb7bdc6c5944e9224a90b 374 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 8 357 3.0E-92 T 22-04-2016 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 L21SP4_RS07750 947a282fb2581b72f7fa8994cad030c6 170 SUPERFAMILY SSF118196 6 148 5.49E-51 T 22-04-2016 IPR023370 TsaA-like domain L21SP4_RS07750 947a282fb2581b72f7fa8994cad030c6 170 ProSitePatterns PS01318 TsaA-like domain signature. 83 94 - T 22-04-2016 IPR023368 Uncharacterised protein family UPF0066, conserved site L21SP4_RS07750 947a282fb2581b72f7fa8994cad030c6 170 TIGRFAM TIGR00104 tRNA_TsaA: tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase TsaA 6 139 4.0E-37 T 22-04-2016 IPR023370 TsaA-like domain L21SP4_RS07750 947a282fb2581b72f7fa8994cad030c6 170 Pfam PF01980 Uncharacterised protein family UPF0066 23 135 5.7E-35 T 22-04-2016 IPR023370 TsaA-like domain L21SP4_RS07750 947a282fb2581b72f7fa8994cad030c6 170 Gene3D G3DSA:2.40.30.70 6 147 3.0E-49 T 22-04-2016 IPR023370 TsaA-like domain L21SP4_RS07750 947a282fb2581b72f7fa8994cad030c6 170 PANTHER PTHR12818 1 159 1.9E-50 T 22-04-2016 L21SP4_RS08005 a119b4942a80dfc976977dc0ca40d9f9 170 PANTHER PTHR22769 18 151 1.0E-29 T 22-04-2016 L21SP4_RS08005 a119b4942a80dfc976977dc0ca40d9f9 170 PRINTS PR01403 7,8-dihydro-8-oxoguanine triphosphatase signature 15 32 7.6E-18 T 22-04-2016 IPR003563 7,8-dihydro-8-oxoguanine triphosphatase GO:0006281|GO:0008413 MetaCyc: PWY-6502 L21SP4_RS08005 a119b4942a80dfc976977dc0ca40d9f9 170 PRINTS PR01403 7,8-dihydro-8-oxoguanine triphosphatase signature 92 111 7.6E-18 T 22-04-2016 IPR003563 7,8-dihydro-8-oxoguanine triphosphatase GO:0006281|GO:0008413 MetaCyc: PWY-6502 L21SP4_RS08005 a119b4942a80dfc976977dc0ca40d9f9 170 PRINTS PR01403 7,8-dihydro-8-oxoguanine triphosphatase signature 112 130 7.6E-18 T 22-04-2016 IPR003563 7,8-dihydro-8-oxoguanine triphosphatase GO:0006281|GO:0008413 MetaCyc: PWY-6502 L21SP4_RS08005 a119b4942a80dfc976977dc0ca40d9f9 170 PRINTS PR01403 7,8-dihydro-8-oxoguanine triphosphatase signature 32 48 7.6E-18 T 22-04-2016 IPR003563 7,8-dihydro-8-oxoguanine triphosphatase GO:0006281|GO:0008413 MetaCyc: PWY-6502 L21SP4_RS08005 a119b4942a80dfc976977dc0ca40d9f9 170 PRINTS PR01403 7,8-dihydro-8-oxoguanine triphosphatase signature 131 149 7.6E-18 T 22-04-2016 IPR003563 7,8-dihydro-8-oxoguanine triphosphatase GO:0006281|GO:0008413 MetaCyc: PWY-6502 L21SP4_RS08005 a119b4942a80dfc976977dc0ca40d9f9 170 PANTHER PTHR22769:SF20 18 151 1.0E-29 T 22-04-2016 L21SP4_RS08005 a119b4942a80dfc976977dc0ca40d9f9 170 Pfam PF00293 NUDIX domain 19 136 2.4E-16 T 22-04-2016 IPR000086 NUDIX hydrolase domain GO:0016787 L21SP4_RS08005 a119b4942a80dfc976977dc0ca40d9f9 170 SUPERFAMILY SSF55811 18 144 2.98E-26 T 22-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 L21SP4_RS08005 a119b4942a80dfc976977dc0ca40d9f9 170 ProSitePatterns PS00893 Nudix box signature. 48 69 - T 22-04-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 L21SP4_RS08005 a119b4942a80dfc976977dc0ca40d9f9 170 Gene3D G3DSA:3.90.79.10 17 156 9.3E-44 T 22-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 L21SP4_RS06070 776005cd150b92566ee34851ef90b4a3 504 SUPERFAMILY SSF56024 290 489 7.4E-39 T 22-04-2016 L21SP4_RS06070 776005cd150b92566ee34851ef90b4a3 504 SMART SM00155 417 444 0.08 T 22-04-2016 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 L21SP4_RS06070 776005cd150b92566ee34851ef90b4a3 504 SMART SM00155 239 266 2.6E-5 T 22-04-2016 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 L21SP4_RS06070 776005cd150b92566ee34851ef90b4a3 504 Pfam PF13091 PLD-like domain 348 467 1.3E-22 T 22-04-2016 IPR025202 Phospholipase D-like domain L21SP4_RS06070 776005cd150b92566ee34851ef90b4a3 504 Pfam PF13091 PLD-like domain 155 298 3.2E-14 T 22-04-2016 IPR025202 Phospholipase D-like domain L21SP4_RS06070 776005cd150b92566ee34851ef90b4a3 504 Gene3D G3DSA:3.30.870.10 133 333 1.1E-41 T 22-04-2016 L21SP4_RS06070 776005cd150b92566ee34851ef90b4a3 504 SUPERFAMILY SSF56024 126 333 1.08E-48 T 22-04-2016 L21SP4_RS06070 776005cd150b92566ee34851ef90b4a3 504 PANTHER PTHR21248:SF5 29 504 4.5E-100 T 22-04-2016 L21SP4_RS06070 776005cd150b92566ee34851ef90b4a3 504 PANTHER PTHR21248 29 504 4.5E-100 T 22-04-2016 L21SP4_RS06070 776005cd150b92566ee34851ef90b4a3 504 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 30 504 2.2E-101 T 22-04-2016 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 L21SP4_RS06070 776005cd150b92566ee34851ef90b4a3 504 Gene3D G3DSA:3.30.870.10 334 480 9.2E-32 T 22-04-2016 L21SP4_RS06070 776005cd150b92566ee34851ef90b4a3 504 Pfam PF13396 Phospholipase_D-nuclease N-terminal 32 70 4.0E-7 T 22-04-2016 IPR027379 Cardiolipin synthase N-terminal L21SP4_RS01005 df0cdd2f2652d74892abdfebab02f2cb 219 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 20 206 1.5E-64 T 22-04-2016 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 L21SP4_RS01005 df0cdd2f2652d74892abdfebab02f2cb 219 PANTHER PTHR23117:SF13 16 218 8.1E-86 T 22-04-2016 L21SP4_RS01005 df0cdd2f2652d74892abdfebab02f2cb 219 Pfam PF00625 Guanylate kinase 21 205 5.6E-45 T 22-04-2016 IPR008145 Guanylate kinase/L-type calcium channel beta subunit L21SP4_RS01005 df0cdd2f2652d74892abdfebab02f2cb 219 ProSitePatterns PS00856 Guanylate kinase-like signature. 52 69 - T 22-04-2016 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 L21SP4_RS01005 df0cdd2f2652d74892abdfebab02f2cb 219 SUPERFAMILY SSF52540 16 211 8.23E-62 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS01005 df0cdd2f2652d74892abdfebab02f2cb 219 Gene3D G3DSA:3.30.63.10 58 99 1.3E-27 T 22-04-2016 L21SP4_RS01005 df0cdd2f2652d74892abdfebab02f2cb 219 SMART SM00072 17 209 1.2E-62 T 22-04-2016 IPR008145 Guanylate kinase/L-type calcium channel beta subunit L21SP4_RS01005 df0cdd2f2652d74892abdfebab02f2cb 219 Gene3D G3DSA:3.40.50.300 100 212 4.5E-41 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS01005 df0cdd2f2652d74892abdfebab02f2cb 219 PANTHER PTHR23117 16 218 8.1E-86 T 22-04-2016 L21SP4_RS01005 df0cdd2f2652d74892abdfebab02f2cb 219 Gene3D G3DSA:3.40.50.300 10 57 6.0E-4 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS01005 df0cdd2f2652d74892abdfebab02f2cb 219 Hamap MF_00328 Guanylate kinase [gmk]. 16 209 34.52 T 22-04-2016 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 L21SP4_RS10270 2a0959d66abcc935ca88b7edbd391516 315 Pfam PF00288 GHMP kinases N terminal domain 92 161 3.1E-5 T 22-04-2016 IPR006204 GHMP kinase N-terminal domain GO:0005524 L21SP4_RS10270 2a0959d66abcc935ca88b7edbd391516 315 SUPERFAMILY SSF55060 181 304 1.13E-20 T 22-04-2016 IPR013750 GHMP kinase, C-terminal domain L21SP4_RS10270 2a0959d66abcc935ca88b7edbd391516 315 PANTHER PTHR10457 6 297 5.2E-36 T 22-04-2016 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 L21SP4_RS10270 2a0959d66abcc935ca88b7edbd391516 315 SUPERFAMILY SSF54211 1 164 4.4E-24 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold L21SP4_RS10270 2a0959d66abcc935ca88b7edbd391516 315 Gene3D G3DSA:3.30.70.890 184 285 7.1E-15 T 22-04-2016 IPR013750 GHMP kinase, C-terminal domain L21SP4_RS10270 2a0959d66abcc935ca88b7edbd391516 315 Pfam PF10509 Galactokinase galactose-binding signature 7 43 8.3E-5 T 22-04-2016 IPR019539 Galactokinase galactose-binding domain KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 L21SP4_RS10270 2a0959d66abcc935ca88b7edbd391516 315 Pfam PF08544 GHMP kinases C terminal 225 293 1.8E-12 T 22-04-2016 IPR013750 GHMP kinase, C-terminal domain L21SP4_RS10270 2a0959d66abcc935ca88b7edbd391516 315 Gene3D G3DSA:3.30.230.10 3 165 2.1E-25 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup L21SP4_RS10270 2a0959d66abcc935ca88b7edbd391516 315 PRINTS PR00959 Mevalonate kinase family signature 10 34 5.4E-11 T 22-04-2016 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 L21SP4_RS10270 2a0959d66abcc935ca88b7edbd391516 315 PRINTS PR00959 Mevalonate kinase family signature 272 289 5.4E-11 T 22-04-2016 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 L21SP4_RS10270 2a0959d66abcc935ca88b7edbd391516 315 PRINTS PR00959 Mevalonate kinase family signature 95 117 5.4E-11 T 22-04-2016 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 L21SP4_RS09110 398a16864da0c90380f23037a1090093 393 PANTHER PTHR36566:SF1 2 392 7.1E-83 T 22-04-2016 L21SP4_RS09110 398a16864da0c90380f23037a1090093 393 Gene3D G3DSA:3.10.20.300 330 390 2.3E-14 T 22-04-2016 L21SP4_RS09110 398a16864da0c90380f23037a1090093 393 Pfam PF01969 Protein of unknown function DUF111 5 379 4.0E-126 T 22-04-2016 IPR002822 Uncharacterised protein family UPF0272 L21SP4_RS09110 398a16864da0c90380f23037a1090093 393 Gene3D G3DSA:3.30.70.1380 244 329 2.2E-24 T 22-04-2016 L21SP4_RS09110 398a16864da0c90380f23037a1090093 393 PANTHER PTHR36566 2 392 7.1E-83 T 22-04-2016 L21SP4_RS09110 398a16864da0c90380f23037a1090093 393 Hamap MF_01074 UPF0272 protein . 1 388 36.4 T 22-04-2016 IPR002822 Uncharacterised protein family UPF0272 L21SP4_RS09110 398a16864da0c90380f23037a1090093 393 TIGRFAM TIGR00299 TIGR00299: TIGR00299 family protein 6 379 4.4E-88 T 22-04-2016 IPR002822 Uncharacterised protein family UPF0272 L21SP4_RS11850 1260a8f83e18a0f579c556aca9a60a51 266 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 252 1.9E-56 T 22-04-2016 L21SP4_RS11850 1260a8f83e18a0f579c556aca9a60a51 266 SUPERFAMILY SSF51735 5 254 9.27E-75 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS11850 1260a8f83e18a0f579c556aca9a60a51 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 2.9E-40 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS11850 1260a8f83e18a0f579c556aca9a60a51 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 2.9E-40 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS11850 1260a8f83e18a0f579c556aca9a60a51 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 2.9E-40 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS11850 1260a8f83e18a0f579c556aca9a60a51 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 2.9E-40 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS11850 1260a8f83e18a0f579c556aca9a60a51 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 2.9E-40 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS11850 1260a8f83e18a0f579c556aca9a60a51 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 2.9E-40 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS11850 1260a8f83e18a0f579c556aca9a60a51 266 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 22-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 L21SP4_RS11850 1260a8f83e18a0f579c556aca9a60a51 266 Gene3D G3DSA:3.40.50.720 4 254 2.5E-78 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS11850 1260a8f83e18a0f579c556aca9a60a51 266 PANTHER PTHR24322:SF536 159 190 1.9E-60 T 22-04-2016 L21SP4_RS11850 1260a8f83e18a0f579c556aca9a60a51 266 PANTHER PTHR24322:SF536 15 143 1.9E-60 T 22-04-2016 L21SP4_RS11850 1260a8f83e18a0f579c556aca9a60a51 266 PANTHER PTHR24322 159 190 1.9E-60 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS11850 1260a8f83e18a0f579c556aca9a60a51 266 PANTHER PTHR24322 15 143 1.9E-60 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS11850 1260a8f83e18a0f579c556aca9a60a51 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 1.7E-9 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS11850 1260a8f83e18a0f579c556aca9a60a51 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 1.7E-9 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS11850 1260a8f83e18a0f579c556aca9a60a51 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 1.7E-9 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS09150 f0e81827ffd738edf2605a7397272175 355 TIGRFAM TIGR04178 exo_archaeo: exosortase/archaeosortase family protein 242 336 1.6E-21 T 22-04-2016 IPR026392 Exosortase/Archaeosortase domain L21SP4_RS09150 f0e81827ffd738edf2605a7397272175 355 Pfam PF09721 Transmembrane exosortase (Exosortase_EpsH) 86 336 8.2E-48 T 22-04-2016 IPR019127 Exosortase EpsH-related KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- L21SP4_RS09150 f0e81827ffd738edf2605a7397272175 355 TIGRFAM TIGR02602 8TM_EpsH: exosortase 103 334 1.1E-49 T 22-04-2016 IPR013426 Exosortase, EpsH L21SP4_RS04025 c4e24ee4edf1d314c9c4018c1639c686 383 TIGRFAM TIGR01109 Na_pump_decarbB: sodium ion-translocating decarboxylase, beta subunit 25 377 1.3E-169 T 22-04-2016 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 L21SP4_RS04025 c4e24ee4edf1d314c9c4018c1639c686 383 Pfam PF03977 Na+-transporting oxaloacetate decarboxylase beta subunit 26 381 3.3E-160 T 22-04-2016 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 L21SP4_RS04025 c4e24ee4edf1d314c9c4018c1639c686 383 PIRSF PIRSF015658 2 383 2.6E-175 T 22-04-2016 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 L21SP4_RS04025 c4e24ee4edf1d314c9c4018c1639c686 383 PANTHER PTHR35806 1 383 1.4E-187 T 22-04-2016 L21SP4_RS06460 922c4136e28c18f9470e00a5be784d3a 280 Pfam PF14236 Domain of unknown function (DUF4338) 41 267 1.1E-64 T 22-04-2016 IPR025639 Domain of unknown function DUF4338 L21SP4_RS11030 922c4136e28c18f9470e00a5be784d3a 280 Pfam PF14236 Domain of unknown function (DUF4338) 41 267 1.1E-64 T 22-04-2016 IPR025639 Domain of unknown function DUF4338 L21SP4_RS08210 d9a1303df516f92ab8e02c858bbb67e2 575 PANTHER PTHR33307 149 406 1.3E-13 T 22-04-2016 L21SP4_RS08210 d9a1303df516f92ab8e02c858bbb67e2 575 PANTHER PTHR33307 66 128 1.3E-13 T 22-04-2016 L21SP4_RS08210 d9a1303df516f92ab8e02c858bbb67e2 575 Pfam PF13088 BNR repeat-like domain 196 367 5.4E-20 T 22-04-2016 IPR011040 Sialidases L21SP4_RS08210 d9a1303df516f92ab8e02c858bbb67e2 575 Gene3D G3DSA:2.120.10.10 61 393 1.3E-46 T 22-04-2016 IPR011040 Sialidases L21SP4_RS08210 d9a1303df516f92ab8e02c858bbb67e2 575 SUPERFAMILY SSF50939 51 397 5.05E-45 T 22-04-2016 IPR011040 Sialidases L21SP4_RS04035 88148040ad99fc744013a41a72c785c0 76 Pfam PF04277 Oxaloacetate decarboxylase, gamma chain 6 73 5.9E-11 T 22-04-2016 IPR005899 Sodium ion-translocating decarboxylase GO:0008948|GO:0015081|GO:0016020|GO:0071436 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 L21SP4_RS04035 88148040ad99fc744013a41a72c785c0 76 TIGRFAM TIGR01195 oadG_fam: sodium pump decarboxylases, gamma subunit 6 75 9.7E-12 T 22-04-2016 IPR005899 Sodium ion-translocating decarboxylase GO:0008948|GO:0015081|GO:0016020|GO:0071436 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 L21SP4_RS09365 ee2e62fc9c383f4ae3c398be4fd58a6f 497 Pfam PF13347 MFS/sugar transport protein 42 470 5.5E-76 T 22-04-2016 L21SP4_RS09365 ee2e62fc9c383f4ae3c398be4fd58a6f 497 Gene3D G3DSA:1.20.1250.20 53 242 6.0E-17 T 22-04-2016 L21SP4_RS09365 ee2e62fc9c383f4ae3c398be4fd58a6f 497 Gene3D G3DSA:1.20.1250.20 258 472 1.1E-14 T 22-04-2016 L21SP4_RS09365 ee2e62fc9c383f4ae3c398be4fd58a6f 497 PANTHER PTHR11328 36 496 7.1E-72 T 22-04-2016 L21SP4_RS09365 ee2e62fc9c383f4ae3c398be4fd58a6f 497 SUPERFAMILY SSF103473 53 472 5.75E-35 T 22-04-2016 IPR020846 Major facilitator superfamily domain L21SP4_RS09365 ee2e62fc9c383f4ae3c398be4fd58a6f 497 ProSitePatterns PS00872 Sodium:galactoside symporter family signature. 91 116 - T 22-04-2016 IPR018043 Sodium:galactoside symporter, conserved site GO:0005215|GO:0006814|GO:0016020 L21SP4_RS09365 ee2e62fc9c383f4ae3c398be4fd58a6f 497 PANTHER PTHR11328:SF24 36 496 7.1E-72 T 22-04-2016 L21SP4_RS11950 7c1c8900e4991582d7cbbc5f273f8561 334 SUPERFAMILY SSF52467 205 324 7.63E-48 T 22-04-2016 IPR029035 DHS-like NAD/FAD-binding domain L21SP4_RS11950 7c1c8900e4991582d7cbbc5f273f8561 334 Gene3D G3DSA:3.40.50.1220 200 326 1.0E-57 T 22-04-2016 IPR029035 DHS-like NAD/FAD-binding domain L21SP4_RS11950 7c1c8900e4991582d7cbbc5f273f8561 334 PANTHER PTHR10909:SF299 136 327 2.0E-54 T 22-04-2016 L21SP4_RS11950 7c1c8900e4991582d7cbbc5f273f8561 334 SUPERFAMILY SSF52402 4 186 1.26E-50 T 22-04-2016 L21SP4_RS11950 7c1c8900e4991582d7cbbc5f273f8561 334 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 205 288 2.2E-36 T 22-04-2016 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal L21SP4_RS11950 7c1c8900e4991582d7cbbc5f273f8561 334 PANTHER PTHR10909 136 327 2.0E-54 T 22-04-2016 L21SP4_RS11950 7c1c8900e4991582d7cbbc5f273f8561 334 PIRSF PIRSF000089 1 330 8.5E-116 T 22-04-2016 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 L21SP4_RS11950 7c1c8900e4991582d7cbbc5f273f8561 334 Gene3D G3DSA:3.40.50.620 4 189 1.1E-64 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP4_RS11950 7c1c8900e4991582d7cbbc5f273f8561 334 SMART SM00893 5 201 7.5E-43 T 22-04-2016 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: REACT_6305 L21SP4_RS11950 7c1c8900e4991582d7cbbc5f273f8561 334 Pfam PF01012 Electron transfer flavoprotein domain 5 184 1.8E-41 T 22-04-2016 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: REACT_6305 L21SP4_RS01335 1fdd4bbdb4a6b8e6aec3b35ab48d1b9c 305 PANTHER PTHR35894 38 301 6.9E-77 T 22-04-2016 L21SP4_RS01335 1fdd4bbdb4a6b8e6aec3b35ab48d1b9c 305 Pfam PF13401 AAA domain 77 206 2.4E-22 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS01335 1fdd4bbdb4a6b8e6aec3b35ab48d1b9c 305 PANTHER PTHR35894:SF1 38 301 6.9E-77 T 22-04-2016 L21SP4_RS01335 1fdd4bbdb4a6b8e6aec3b35ab48d1b9c 305 SMART SM00382 78 220 2.0E-4 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS01335 1fdd4bbdb4a6b8e6aec3b35ab48d1b9c 305 SUPERFAMILY SSF52540 41 300 6.04E-31 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS01335 1fdd4bbdb4a6b8e6aec3b35ab48d1b9c 305 Gene3D G3DSA:3.40.50.300 64 218 2.5E-17 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS02330 7e465567e0ebc1a79c1f2284ebf47cd4 373 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 3 368 6.1E-111 T 22-04-2016 IPR004381 Glycerate kinase GO:0008887|GO:0031388 L21SP4_RS02330 7e465567e0ebc1a79c1f2284ebf47cd4 373 Pfam PF02595 Glycerate kinase family 4 368 8.7E-115 T 22-04-2016 IPR004381 Glycerate kinase GO:0008887|GO:0031388 L21SP4_RS02330 7e465567e0ebc1a79c1f2284ebf47cd4 373 Gene3D G3DSA:3.90.1510.10 42 275 7.5E-73 T 22-04-2016 IPR018193 Glycerate kinase, flavodoxin-like domain GO:0008887|GO:0031388 L21SP4_RS02330 7e465567e0ebc1a79c1f2284ebf47cd4 373 SUPERFAMILY SSF110738 1 368 4.84E-99 T 22-04-2016 IPR004381 Glycerate kinase GO:0008887|GO:0031388 L21SP4_RS02330 7e465567e0ebc1a79c1f2284ebf47cd4 373 PIRSF PIRSF006078 1 372 4.4E-116 T 22-04-2016 IPR004381 Glycerate kinase GO:0008887|GO:0031388 L21SP4_RS02330 7e465567e0ebc1a79c1f2284ebf47cd4 373 PANTHER PTHR21599 1 369 2.5E-103 T 22-04-2016 IPR004381 Glycerate kinase GO:0008887|GO:0031388 L21SP4_RS02330 7e465567e0ebc1a79c1f2284ebf47cd4 373 PANTHER PTHR21599:SF0 1 369 2.5E-103 T 22-04-2016 L21SP4_RS06145 0a265aca3dab586b6f1a619262e2227c 456 PIRSF PIRSF500133 1 455 5.5E-222 T 22-04-2016 IPR028356 UDP-glucose 6-dehydrogenase, eukaryotic type GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00500+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|UniPathway: UPA00038 L21SP4_RS06145 0a265aca3dab586b6f1a619262e2227c 456 SUPERFAMILY SSF48179 211 310 7.48E-27 T 22-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 L21SP4_RS06145 0a265aca3dab586b6f1a619262e2227c 456 Gene3D G3DSA:1.20.5.100 214 240 8.2E-14 T 22-04-2016 L21SP4_RS06145 0a265aca3dab586b6f1a619262e2227c 456 PANTHER PTHR11374 3 455 2.5E-290 T 22-04-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 L21SP4_RS06145 0a265aca3dab586b6f1a619262e2227c 456 Gene3D G3DSA:3.40.50.720 4 213 1.3E-74 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS06145 0a265aca3dab586b6f1a619262e2227c 456 PIRSF PIRSF000124 3 450 2.5E-129 T 22-04-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 L21SP4_RS06145 0a265aca3dab586b6f1a619262e2227c 456 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 329 434 6.6E-30 T 22-04-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 L21SP4_RS06145 0a265aca3dab586b6f1a619262e2227c 456 SMART SM00984 329 435 1.2E-38 T 22-04-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 L21SP4_RS06145 0a265aca3dab586b6f1a619262e2227c 456 SUPERFAMILY SSF51735 3 202 7.29E-42 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS06145 0a265aca3dab586b6f1a619262e2227c 456 PANTHER PTHR11374:SF3 3 455 2.5E-290 T 22-04-2016 L21SP4_RS06145 0a265aca3dab586b6f1a619262e2227c 456 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 4 431 1.1E-99 T 22-04-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 L21SP4_RS06145 0a265aca3dab586b6f1a619262e2227c 456 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 4 187 3.4E-61 T 22-04-2016 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 L21SP4_RS06145 0a265aca3dab586b6f1a619262e2227c 456 Gene3D G3DSA:3.40.50.720 243 454 2.0E-83 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS06145 0a265aca3dab586b6f1a619262e2227c 456 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 211 305 1.5E-30 T 22-04-2016 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 L21SP4_RS06145 0a265aca3dab586b6f1a619262e2227c 456 SUPERFAMILY SSF52413 316 446 1.2E-30 T 22-04-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 L21SP4_RS06060 52c25d35bcf883e611f6c9a6c18f74b6 285 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 132 143 - T 22-04-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 L21SP4_RS06060 52c25d35bcf883e611f6c9a6c18f74b6 285 SUPERFAMILY SSF51569 3 272 3.81E-75 T 22-04-2016 L21SP4_RS06060 52c25d35bcf883e611f6c9a6c18f74b6 285 PIRSF PIRSF001359 1 283 9.5E-76 T 22-04-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 L21SP4_RS06060 52c25d35bcf883e611f6c9a6c18f74b6 285 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 3 280 4.2E-72 T 22-04-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 L21SP4_RS06060 52c25d35bcf883e611f6c9a6c18f74b6 285 PANTHER PTHR30304 1 233 1.2E-66 T 22-04-2016 L21SP4_RS06060 52c25d35bcf883e611f6c9a6c18f74b6 285 Pfam PF01116 Fructose-bisphosphate aldolase class-II 5 280 4.8E-82 T 22-04-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 L21SP4_RS06060 52c25d35bcf883e611f6c9a6c18f74b6 285 Gene3D G3DSA:3.20.20.70 1 281 4.7E-85 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP4_RS04615 99c14801564991de6196c558a5395d38 476 ProSitePatterns PS00872 Sodium:galactoside symporter family signature. 72 97 - T 22-04-2016 IPR018043 Sodium:galactoside symporter, conserved site GO:0005215|GO:0006814|GO:0016020 L21SP4_RS04615 99c14801564991de6196c558a5395d38 476 SUPERFAMILY SSF103473 23 469 1.31E-33 T 22-04-2016 IPR020846 Major facilitator superfamily domain L21SP4_RS04615 99c14801564991de6196c558a5395d38 476 Pfam PF13347 MFS/sugar transport protein 24 458 2.4E-77 T 22-04-2016 L21SP4_RS04615 99c14801564991de6196c558a5395d38 476 PANTHER PTHR11328 23 475 9.2E-78 T 22-04-2016 L21SP4_RS04615 99c14801564991de6196c558a5395d38 476 Gene3D G3DSA:1.20.1250.20 250 465 3.6E-13 T 22-04-2016 L21SP4_RS04615 99c14801564991de6196c558a5395d38 476 Gene3D G3DSA:1.20.1250.20 26 230 9.5E-14 T 22-04-2016 L21SP4_RS04615 99c14801564991de6196c558a5395d38 476 PANTHER PTHR11328:SF24 23 475 9.2E-78 T 22-04-2016 L21SP4_RS02050 a6bb4c3a9e085f2045c6ead8daf5f0be 477 Pfam PF00884 Sulfatase 28 334 9.3E-54 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS02050 a6bb4c3a9e085f2045c6ead8daf5f0be 477 SUPERFAMILY SSF53649 26 446 5.96E-105 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS02050 a6bb4c3a9e085f2045c6ead8daf5f0be 477 PANTHER PTHR10342 1 465 1.7E-94 T 22-04-2016 L21SP4_RS02050 a6bb4c3a9e085f2045c6ead8daf5f0be 477 Gene3D G3DSA:3.40.720.10 25 352 8.8E-89 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS02050 a6bb4c3a9e085f2045c6ead8daf5f0be 477 PANTHER PTHR10342:SF237 1 465 1.7E-94 T 22-04-2016 L21SP4_RS02050 a6bb4c3a9e085f2045c6ead8daf5f0be 477 Pfam PF16347 Domain of unknown function (DUF4976) 387 446 5.2E-9 T 22-04-2016 IPR032506 Domain of unknown function DUF4976 L21SP4_RS02050 a6bb4c3a9e085f2045c6ead8daf5f0be 477 ProSitePatterns PS00149 Sulfatases signature 2. 116 126 - T 22-04-2016 IPR024607 Sulfatase, conserved site L21SP4_RS02050 a6bb4c3a9e085f2045c6ead8daf5f0be 477 Gene3D G3DSA:3.30.1120.10 387 453 1.4E-13 T 22-04-2016 L21SP4_RS06180 2cd242aedf9a18954d017f48d673262f 93 PANTHER PTHR34404:SF2 2 75 6.3E-19 T 22-04-2016 L21SP4_RS06180 2cd242aedf9a18954d017f48d673262f 93 SMART SM00834 1 41 2.9E-20 T 22-04-2016 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain L21SP4_RS06180 2cd242aedf9a18954d017f48d673262f 93 Pfam PF09723 Zinc ribbon domain 1 39 5.8E-18 T 22-04-2016 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain L21SP4_RS06180 2cd242aedf9a18954d017f48d673262f 93 PANTHER PTHR34404 2 75 6.3E-19 T 22-04-2016 L21SP4_RS06180 2cd242aedf9a18954d017f48d673262f 93 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 1 52 3.1E-22 T 22-04-2016 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain L21SP4_RS07590 a75f216a5f857cee9fe8bd74bb16aacf 428 PANTHER PTHR23083 60 271 1.4E-39 T 22-04-2016 L21SP4_RS07590 a75f216a5f857cee9fe8bd74bb16aacf 428 PANTHER PTHR23083 315 407 1.4E-39 T 22-04-2016 L21SP4_RS07590 a75f216a5f857cee9fe8bd74bb16aacf 428 SUPERFAMILY SSF48452 312 410 6.88E-11 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS07590 a75f216a5f857cee9fe8bd74bb16aacf 428 SMART SM00028 236 269 110.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS07590 a75f216a5f857cee9fe8bd74bb16aacf 428 SMART SM00028 202 235 31.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS07590 a75f216a5f857cee9fe8bd74bb16aacf 428 SMART SM00028 100 133 120.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS07590 a75f216a5f857cee9fe8bd74bb16aacf 428 SMART SM00028 168 201 11.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS07590 a75f216a5f857cee9fe8bd74bb16aacf 428 SMART SM00028 66 99 2.4 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS07590 a75f216a5f857cee9fe8bd74bb16aacf 428 SMART SM00028 347 380 280.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS07590 a75f216a5f857cee9fe8bd74bb16aacf 428 SMART SM00028 313 346 15.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS07590 a75f216a5f857cee9fe8bd74bb16aacf 428 SMART SM00028 134 167 0.57 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS07590 a75f216a5f857cee9fe8bd74bb16aacf 428 SUPERFAMILY SSF48452 69 264 2.2E-24 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS07590 a75f216a5f857cee9fe8bd74bb16aacf 428 Pfam PF14559 Tetratricopeptide repeat 144 210 1.6E-8 T 22-04-2016 L21SP4_RS07590 a75f216a5f857cee9fe8bd74bb16aacf 428 Pfam PF13432 Tetratricopeptide repeat 71 129 5.0E-9 T 22-04-2016 L21SP4_RS07590 a75f216a5f857cee9fe8bd74bb16aacf 428 Gene3D G3DSA:1.25.40.10 313 409 6.9E-11 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS07590 a75f216a5f857cee9fe8bd74bb16aacf 428 Gene3D G3DSA:1.25.40.10 181 264 7.5E-16 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS07590 a75f216a5f857cee9fe8bd74bb16aacf 428 Gene3D G3DSA:1.25.40.10 70 180 2.2E-23 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS04825 9f0752ebc84ae5930d45242ea08bf75e 860 PANTHER PTHR24423 335 623 5.9E-151 T 22-04-2016 L21SP4_RS04825 9f0752ebc84ae5930d45242ea08bf75e 860 PANTHER PTHR24423 738 860 5.9E-151 T 22-04-2016 L21SP4_RS04825 9f0752ebc84ae5930d45242ea08bf75e 860 SMART SM00387 468 583 7.9E-41 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS04825 9f0752ebc84ae5930d45242ea08bf75e 860 SUPERFAMILY SSF52172 601 724 5.41E-23 T 22-04-2016 IPR011006 CheY-like superfamily L21SP4_RS04825 9f0752ebc84ae5930d45242ea08bf75e 860 SMART SM00448 602 713 1.9E-16 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 L21SP4_RS04825 9f0752ebc84ae5930d45242ea08bf75e 860 SMART SM00448 739 852 4.4E-36 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 L21SP4_RS04825 9f0752ebc84ae5930d45242ea08bf75e 860 PANTHER PTHR24423:SF382 335 623 5.9E-151 T 22-04-2016 L21SP4_RS04825 9f0752ebc84ae5930d45242ea08bf75e 860 PANTHER PTHR24423:SF382 738 860 5.9E-151 T 22-04-2016 L21SP4_RS04825 9f0752ebc84ae5930d45242ea08bf75e 860 SUPERFAMILY SSF47384 339 423 4.32E-22 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS04825 9f0752ebc84ae5930d45242ea08bf75e 860 Gene3D G3DSA:3.40.190.10 131 217 2.6E-5 T 22-04-2016 L21SP4_RS04825 9f0752ebc84ae5930d45242ea08bf75e 860 Gene3D G3DSA:3.40.50.2300 732 855 1.2E-39 T 22-04-2016 L21SP4_RS04825 9f0752ebc84ae5930d45242ea08bf75e 860 Gene3D G3DSA:1.10.287.130 352 417 6.4E-16 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS04825 9f0752ebc84ae5930d45242ea08bf75e 860 Pfam PF00512 His Kinase A (phospho-acceptor) domain 357 421 6.2E-19 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS04825 9f0752ebc84ae5930d45242ea08bf75e 860 Gene3D G3DSA:3.40.50.2300 613 725 4.5E-24 T 22-04-2016 L21SP4_RS04825 9f0752ebc84ae5930d45242ea08bf75e 860 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 28 279 2.0E-36 T 22-04-2016 L21SP4_RS04825 9f0752ebc84ae5930d45242ea08bf75e 860 Pfam PF00072 Response regulator receiver domain 741 852 5.0E-26 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 L21SP4_RS04825 9f0752ebc84ae5930d45242ea08bf75e 860 Pfam PF00072 Response regulator receiver domain 604 713 2.3E-13 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 L21SP4_RS04825 9f0752ebc84ae5930d45242ea08bf75e 860 SUPERFAMILY SSF52172 737 856 2.7E-37 T 22-04-2016 IPR011006 CheY-like superfamily L21SP4_RS04825 9f0752ebc84ae5930d45242ea08bf75e 860 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 468 580 7.1E-29 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS04825 9f0752ebc84ae5930d45242ea08bf75e 860 SUPERFAMILY SSF55874 410 579 2.36E-48 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS04825 9f0752ebc84ae5930d45242ea08bf75e 860 SUPERFAMILY SSF53850 22 217 2.18E-14 T 22-04-2016 L21SP4_RS04825 9f0752ebc84ae5930d45242ea08bf75e 860 Gene3D G3DSA:3.30.565.10 443 612 3.3E-50 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS04825 9f0752ebc84ae5930d45242ea08bf75e 860 SMART SM00388 356 421 8.4E-25 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS04825 9f0752ebc84ae5930d45242ea08bf75e 860 PRINTS PR00344 Bacterial sensor protein C-terminal signature 526 536 3.4E-14 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS04825 9f0752ebc84ae5930d45242ea08bf75e 860 PRINTS PR00344 Bacterial sensor protein C-terminal signature 567 580 3.4E-14 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS04825 9f0752ebc84ae5930d45242ea08bf75e 860 PRINTS PR00344 Bacterial sensor protein C-terminal signature 543 561 3.4E-14 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS04825 9f0752ebc84ae5930d45242ea08bf75e 860 PRINTS PR00344 Bacterial sensor protein C-terminal signature 508 522 3.4E-14 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS11350 e0e58a902fe4f51408dad6365288ff4c 575 Gene3D G3DSA:3.10.400.10 6 184 2.6E-70 T 22-04-2016 L21SP4_RS11350 e0e58a902fe4f51408dad6365288ff4c 575 PANTHER PTHR11055 7 396 1.8E-203 T 22-04-2016 L21SP4_RS11350 e0e58a902fe4f51408dad6365288ff4c 575 SUPERFAMILY SSF88697 6 170 2.98E-53 T 22-04-2016 IPR015947 PUA-like domain L21SP4_RS11350 e0e58a902fe4f51408dad6365288ff4c 575 PANTHER PTHR11055:SF2 7 396 1.8E-203 T 22-04-2016 L21SP4_RS11350 e0e58a902fe4f51408dad6365288ff4c 575 Pfam PF01747 ATP-sulfurylase 173 387 1.3E-91 T 22-04-2016 IPR024951 Sulphate adenylyltransferase catalytic domain GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|UniPathway: UPA00140 L21SP4_RS11350 e0e58a902fe4f51408dad6365288ff4c 575 Pfam PF14306 PUA-like domain 6 162 1.1E-55 T 22-04-2016 IPR025980 ATP-sulfurylase PUA-like domain KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|UniPathway: UPA00140 L21SP4_RS11350 e0e58a902fe4f51408dad6365288ff4c 575 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 386 561 1.5E-59 T 22-04-2016 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: REACT_13433|UniPathway: UPA00140 L21SP4_RS11350 e0e58a902fe4f51408dad6365288ff4c 575 TIGRFAM TIGR00339 sopT: sulfate adenylyltransferase 8 387 3.8E-143 T 22-04-2016 IPR002650 Sulphate adenylyltransferase GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: REACT_13433|UniPathway: UPA00140 L21SP4_RS11350 e0e58a902fe4f51408dad6365288ff4c 575 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 394 568 32.485 T 22-04-2016 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: REACT_13433|UniPathway: UPA00140 L21SP4_RS11350 e0e58a902fe4f51408dad6365288ff4c 575 Gene3D G3DSA:3.40.50.300 387 570 3.6E-69 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS11350 e0e58a902fe4f51408dad6365288ff4c 575 SUPERFAMILY SSF52374 173 390 3.31E-91 T 22-04-2016 L21SP4_RS11350 e0e58a902fe4f51408dad6365288ff4c 575 Gene3D G3DSA:3.40.50.620 185 386 3.8E-95 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP4_RS11350 e0e58a902fe4f51408dad6365288ff4c 575 SUPERFAMILY SSF52540 393 566 1.83E-34 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS11350 e0e58a902fe4f51408dad6365288ff4c 575 Pfam PF01583 Adenylylsulphate kinase 395 550 9.3E-61 T 22-04-2016 L21SP4_RS09800 87d5d3db36935d3bea6dca783f26b5e4 708 Gene3D G3DSA:3.40.30.10 36 146 5.0E-34 T 22-04-2016 IPR012336 Thioredoxin-like fold L21SP4_RS09800 87d5d3db36935d3bea6dca783f26b5e4 708 Gene3D G3DSA:1.50.10.10 382 555 7.0E-41 T 22-04-2016 IPR012341 Six-hairpin glycosidase GO:0003824 L21SP4_RS09800 87d5d3db36935d3bea6dca783f26b5e4 708 Gene3D G3DSA:1.50.10.10 203 338 7.0E-41 T 22-04-2016 IPR012341 Six-hairpin glycosidase GO:0003824 L21SP4_RS09800 87d5d3db36935d3bea6dca783f26b5e4 708 PANTHER PTHR12145 18 703 0.0 T 22-04-2016 L21SP4_RS09800 87d5d3db36935d3bea6dca783f26b5e4 708 Pfam PF03190 Protein of unknown function, DUF255 19 179 9.4E-77 T 22-04-2016 IPR004879 Domain of unknown function DUF255 L21SP4_RS09800 87d5d3db36935d3bea6dca783f26b5e4 708 PANTHER PTHR12145:SF11 18 703 0.0 T 22-04-2016 L21SP4_RS09800 87d5d3db36935d3bea6dca783f26b5e4 708 SUPERFAMILY SSF48208 205 562 1.91E-86 T 22-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP4_RS09800 87d5d3db36935d3bea6dca783f26b5e4 708 Pfam PF07221 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) 236 332 0.043 T 22-04-2016 L21SP4_RS09800 87d5d3db36935d3bea6dca783f26b5e4 708 Pfam PF07221 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) 487 555 0.17 T 22-04-2016 L21SP4_RS09800 87d5d3db36935d3bea6dca783f26b5e4 708 SUPERFAMILY SSF52833 19 145 6.02E-31 T 22-04-2016 IPR012336 Thioredoxin-like fold L21SP4_RS09800 87d5d3db36935d3bea6dca783f26b5e4 708 PIRSF PIRSF006402 15 707 7.7E-255 T 22-04-2016 IPR024705 Spermatogenesis-associated protein 20 L21SP4_RS03590 88f4abdfe0732757875dcaeb12c1a76c 454 Gene3D G3DSA:3.40.120.10 182 256 8.4E-24 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP4_RS03590 88f4abdfe0732757875dcaeb12c1a76c 454 Gene3D G3DSA:3.30.310.50 367 449 4.5E-15 T 22-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP4_RS03590 88f4abdfe0732757875dcaeb12c1a76c 454 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 264 373 2.2E-33 T 22-04-2016 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP4_RS03590 88f4abdfe0732757875dcaeb12c1a76c 454 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 1 451 45.392 T 22-04-2016 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP4_RS03590 88f4abdfe0732757875dcaeb12c1a76c 454 Gene3D G3DSA:3.40.120.10 2 144 1.7E-45 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP4_RS03590 88f4abdfe0732757875dcaeb12c1a76c 454 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 380 448 3.2E-14 T 22-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP4_RS03590 88f4abdfe0732757875dcaeb12c1a76c 454 PANTHER PTHR22573:SF15 1 453 6.5E-155 T 22-04-2016 L21SP4_RS03590 88f4abdfe0732757875dcaeb12c1a76c 454 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 163 260 4.7E-17 T 22-04-2016 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP4_RS03590 88f4abdfe0732757875dcaeb12c1a76c 454 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 98 112 5.1E-12 T 22-04-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP4_RS03590 88f4abdfe0732757875dcaeb12c1a76c 454 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 180 199 5.1E-12 T 22-04-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP4_RS03590 88f4abdfe0732757875dcaeb12c1a76c 454 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 240 255 5.1E-12 T 22-04-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP4_RS03590 88f4abdfe0732757875dcaeb12c1a76c 454 PANTHER PTHR22573 1 453 6.5E-155 T 22-04-2016 L21SP4_RS03590 88f4abdfe0732757875dcaeb12c1a76c 454 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 138 7.1E-41 T 22-04-2016 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP4_RS03590 88f4abdfe0732757875dcaeb12c1a76c 454 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 99 108 - T 22-04-2016 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP4_RS03590 88f4abdfe0732757875dcaeb12c1a76c 454 SUPERFAMILY SSF53738 265 371 1.57E-32 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP4_RS03590 88f4abdfe0732757875dcaeb12c1a76c 454 SUPERFAMILY SSF55957 364 453 1.24E-21 T 22-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP4_RS03590 88f4abdfe0732757875dcaeb12c1a76c 454 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 5 449 1.5E-179 T 22-04-2016 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP4_RS03590 88f4abdfe0732757875dcaeb12c1a76c 454 SUPERFAMILY SSF53738 162 262 2.12E-28 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP4_RS03590 88f4abdfe0732757875dcaeb12c1a76c 454 Gene3D G3DSA:3.40.120.10 257 366 3.4E-37 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP4_RS03590 88f4abdfe0732757875dcaeb12c1a76c 454 SUPERFAMILY SSF53738 3 187 1.73E-45 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP4_RS01680 33240c3a5cc67ed4555f3c1b56f3962c 238 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 163 187 - T 22-04-2016 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 L21SP4_RS01680 33240c3a5cc67ed4555f3c1b56f3962c 238 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 8 230 1.1E-97 T 22-04-2016 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 L21SP4_RS01680 33240c3a5cc67ed4555f3c1b56f3962c 238 PANTHER PTHR12534 8 238 1.2E-104 T 22-04-2016 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 L21SP4_RS01680 33240c3a5cc67ed4555f3c1b56f3962c 238 Pfam PF00318 Ribosomal protein S2 13 229 8.5E-89 T 22-04-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS01680 33240c3a5cc67ed4555f3c1b56f3962c 238 PRINTS PR00395 Ribosomal protein S2 signature 201 215 1.6E-34 T 22-04-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS01680 33240c3a5cc67ed4555f3c1b56f3962c 238 PRINTS PR00395 Ribosomal protein S2 signature 180 191 1.6E-34 T 22-04-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS01680 33240c3a5cc67ed4555f3c1b56f3962c 238 PRINTS PR00395 Ribosomal protein S2 signature 10 28 1.6E-34 T 22-04-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS01680 33240c3a5cc67ed4555f3c1b56f3962c 238 PRINTS PR00395 Ribosomal protein S2 signature 163 180 1.6E-34 T 22-04-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS01680 33240c3a5cc67ed4555f3c1b56f3962c 238 PRINTS PR00395 Ribosomal protein S2 signature 41 50 1.6E-34 T 22-04-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS01680 33240c3a5cc67ed4555f3c1b56f3962c 238 PRINTS PR00395 Ribosomal protein S2 signature 91 108 1.6E-34 T 22-04-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS01680 33240c3a5cc67ed4555f3c1b56f3962c 238 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 6 230 39.572 T 22-04-2016 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 L21SP4_RS01680 33240c3a5cc67ed4555f3c1b56f3962c 238 Gene3D G3DSA:3.40.50.10490 163 236 2.0E-57 T 22-04-2016 L21SP4_RS01680 33240c3a5cc67ed4555f3c1b56f3962c 238 Gene3D G3DSA:3.40.50.10490 27 103 2.0E-57 T 22-04-2016 L21SP4_RS01680 33240c3a5cc67ed4555f3c1b56f3962c 238 Gene3D G3DSA:1.10.287.610 104 157 2.8E-22 T 22-04-2016 L21SP4_RS01680 33240c3a5cc67ed4555f3c1b56f3962c 238 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 10 21 - T 22-04-2016 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 L21SP4_RS01680 33240c3a5cc67ed4555f3c1b56f3962c 238 SUPERFAMILY SSF52313 10 235 6.41E-85 T 22-04-2016 IPR023591 Ribosomal protein S2, flavodoxin-like domain L21SP4_RS11645 b55c915b8c23c978e1fad9bc08a8e06c 415 Gene3D G3DSA:3.20.20.210 195 387 4.1E-6 T 22-04-2016 L21SP4_RS01650 a5613f8e9eda4891d46ec4ab2f3d28cc 294 Pfam PF02574 Homocysteine S-methyltransferase 15 291 2.2E-63 T 22-04-2016 IPR003726 Homocysteine-binding domain L21SP4_RS01650 a5613f8e9eda4891d46ec4ab2f3d28cc 294 SUPERFAMILY SSF82282 9 293 6.8E-89 T 22-04-2016 IPR003726 Homocysteine-binding domain L21SP4_RS01650 a5613f8e9eda4891d46ec4ab2f3d28cc 294 Gene3D G3DSA:3.20.20.330 2 293 8.0E-90 T 22-04-2016 IPR003726 Homocysteine-binding domain L21SP4_RS01650 a5613f8e9eda4891d46ec4ab2f3d28cc 294 PANTHER PTHR21091:SF97 15 290 1.6E-62 T 22-04-2016 L21SP4_RS01650 a5613f8e9eda4891d46ec4ab2f3d28cc 294 PIRSF PIRSF037505 12 293 2.5E-15 T 22-04-2016 IPR017226 Betaine-homocysteine S-methyltransferase, BHMT GO:0005737|GO:0008270|GO:0009086|GO:0047150 UniPathway: UPA00051 L21SP4_RS01650 a5613f8e9eda4891d46ec4ab2f3d28cc 294 PANTHER PTHR21091 15 290 1.6E-62 T 22-04-2016 L21SP4_RS02080 d3af620e250ac88b4417889358dbb01a 378 SUPERFAMILY SSF51726 1 370 9.24E-35 T 22-04-2016 L21SP4_RS02080 d3af620e250ac88b4417889358dbb01a 378 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 112 370 2.3E-20 T 22-04-2016 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 L21SP4_RS02080 d3af620e250ac88b4417889358dbb01a 378 Gene3D G3DSA:3.20.20.210 1 369 2.6E-34 T 22-04-2016 L21SP4_RS06985 7aeae04059842f87844057ebf0372555 178 Pfam PF00578 AhpC/TSA family 54 148 9.1E-10 T 22-04-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15 L21SP4_RS06985 7aeae04059842f87844057ebf0372555 178 SUPERFAMILY SSF52833 4 172 6.03E-22 T 22-04-2016 IPR012336 Thioredoxin-like fold L21SP4_RS06985 7aeae04059842f87844057ebf0372555 178 Gene3D G3DSA:3.40.30.10 2 173 1.6E-25 T 22-04-2016 IPR012336 Thioredoxin-like fold L21SP4_RS06985 7aeae04059842f87844057ebf0372555 178 ProSitePatterns PS00194 Thioredoxin family active site. 58 76 - T 22-04-2016 IPR017937 Thioredoxin, conserved site GO:0045454 L21SP4_RS09540 73af4db5e69ccb206792ad924ebe0a31 202 Gene3D G3DSA:1.10.10.10 138 200 3.0E-22 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS09540 73af4db5e69ccb206792ad924ebe0a31 202 Gene3D G3DSA:1.10.1740.10 15 119 6.3E-37 T 22-04-2016 L21SP4_RS09540 73af4db5e69ccb206792ad924ebe0a31 202 Pfam PF08281 Sigma-70, region 4 142 191 3.9E-14 T 22-04-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP4_RS09540 73af4db5e69ccb206792ad924ebe0a31 202 PANTHER PTHR30173 8 202 7.5E-56 T 22-04-2016 L21SP4_RS09540 73af4db5e69ccb206792ad924ebe0a31 202 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 31 197 2.8E-36 T 22-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP4_RS09540 73af4db5e69ccb206792ad924ebe0a31 202 SUPERFAMILY SSF88659 138 197 1.31E-15 T 22-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP4_RS09540 73af4db5e69ccb206792ad924ebe0a31 202 SUPERFAMILY SSF88946 10 112 1.46E-32 T 22-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP4_RS09540 73af4db5e69ccb206792ad924ebe0a31 202 Pfam PF04542 Sigma-70 region 2 35 102 1.9E-20 T 22-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP4_RS06030 8bc776167537333de6c9c36eb4660bfa 874 SUPERFAMILY SSF48208 108 514 2.8E-45 T 22-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP4_RS06030 8bc776167537333de6c9c36eb4660bfa 874 Gene3D G3DSA:2.60.120.260 720 849 9.5E-15 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS06030 8bc776167537333de6c9c36eb4660bfa 874 SUPERFAMILY SSF49785 717 850 8.14E-16 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS03530 db2be2b33edb171c91396dbdd7e02bdc 355 Gene3D G3DSA:3.40.630.10 166 348 7.2E-78 T 22-04-2016 L21SP4_RS03530 db2be2b33edb171c91396dbdd7e02bdc 355 Gene3D G3DSA:3.40.630.10 2 71 7.2E-78 T 22-04-2016 L21SP4_RS03530 db2be2b33edb171c91396dbdd7e02bdc 355 PANTHER PTHR32481 1 355 2.9E-159 T 22-04-2016 L21SP4_RS03530 db2be2b33edb171c91396dbdd7e02bdc 355 Gene3D G3DSA:2.40.30.40 72 160 9.2E-34 T 22-04-2016 IPR023367 Peptidase M42, domain 2 L21SP4_RS03530 db2be2b33edb171c91396dbdd7e02bdc 355 SUPERFAMILY SSF101821 70 177 8.7E-27 T 22-04-2016 L21SP4_RS03530 db2be2b33edb171c91396dbdd7e02bdc 355 PIRSF PIRSF001123 2 352 4.4E-108 T 22-04-2016 IPR008007 Peptidase M42 L21SP4_RS03530 db2be2b33edb171c91396dbdd7e02bdc 355 PANTHER PTHR32481:SF10 1 355 2.9E-159 T 22-04-2016 L21SP4_RS03530 db2be2b33edb171c91396dbdd7e02bdc 355 SUPERFAMILY SSF53187 6 82 4.65E-63 T 22-04-2016 L21SP4_RS03530 db2be2b33edb171c91396dbdd7e02bdc 355 SUPERFAMILY SSF53187 172 344 4.65E-63 T 22-04-2016 L21SP4_RS03530 db2be2b33edb171c91396dbdd7e02bdc 355 Pfam PF05343 M42 glutamyl aminopeptidase 51 338 2.2E-92 T 22-04-2016 IPR008007 Peptidase M42 L21SP4_RS09060 41d7a8fb4b48fa4b5705d61662d1e9d6 426 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 287 294 - T 22-04-2016 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 L21SP4_RS09060 41d7a8fb4b48fa4b5705d61662d1e9d6 426 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 328 419 3.0E-29 T 22-04-2016 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 L21SP4_RS09060 41d7a8fb4b48fa4b5705d61662d1e9d6 426 SUPERFAMILY SSF52440 1 101 4.75E-32 T 22-04-2016 IPR016185 Pre-ATP-grasp domain L21SP4_RS09060 41d7a8fb4b48fa4b5705d61662d1e9d6 426 Gene3D G3DSA:3.30.1490.20 121 188 2.7E-26 T 22-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 L21SP4_RS09060 41d7a8fb4b48fa4b5705d61662d1e9d6 426 Gene3D G3DSA:3.30.470.20 190 325 1.8E-60 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 L21SP4_RS09060 41d7a8fb4b48fa4b5705d61662d1e9d6 426 Gene3D G3DSA:3.40.50.20 2 93 4.5E-33 T 22-04-2016 IPR016185 Pre-ATP-grasp domain L21SP4_RS09060 41d7a8fb4b48fa4b5705d61662d1e9d6 426 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 421 4.1E-163 T 22-04-2016 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 L21SP4_RS09060 41d7a8fb4b48fa4b5705d61662d1e9d6 426 SMART SM01210 327 421 2.5E-50 T 22-04-2016 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 L21SP4_RS09060 41d7a8fb4b48fa4b5705d61662d1e9d6 426 SUPERFAMILY SSF51246 326 421 3.71E-31 T 22-04-2016 IPR011054 Rudiment single hybrid motif L21SP4_RS09060 41d7a8fb4b48fa4b5705d61662d1e9d6 426 SUPERFAMILY SSF56059 102 322 4.42E-62 T 22-04-2016 L21SP4_RS09060 41d7a8fb4b48fa4b5705d61662d1e9d6 426 Gene3D G3DSA:3.90.600.10 327 421 4.9E-34 T 22-04-2016 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 L21SP4_RS09060 41d7a8fb4b48fa4b5705d61662d1e9d6 426 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 101 293 3.1E-77 T 22-04-2016 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 L21SP4_RS09060 41d7a8fb4b48fa4b5705d61662d1e9d6 426 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 100 1.4E-31 T 22-04-2016 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 L21SP4_RS09060 41d7a8fb4b48fa4b5705d61662d1e9d6 426 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 421 42.012 T 22-04-2016 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 L21SP4_RS09060 41d7a8fb4b48fa4b5705d61662d1e9d6 426 SMART SM01209 101 293 1.7E-129 T 22-04-2016 L21SP4_RS09060 41d7a8fb4b48fa4b5705d61662d1e9d6 426 PANTHER PTHR10520 1 424 2.0E-245 T 22-04-2016 L21SP4_RS08345 8674c482c1a7d1a460c93ec9e656cfe9 183 Pfam PF00673 ribosomal L5P family C-terminus 85 177 1.9E-39 T 22-04-2016 IPR031309 Ribosomal protein L5, C-terminal L21SP4_RS08345 8674c482c1a7d1a460c93ec9e656cfe9 183 SUPERFAMILY SSF55282 4 178 1.2E-65 T 22-04-2016 IPR022803 Ribosomal protein L5 domain L21SP4_RS08345 8674c482c1a7d1a460c93ec9e656cfe9 183 PIRSF PIRSF002161 1 183 2.7E-59 T 22-04-2016 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 L21SP4_RS08345 8674c482c1a7d1a460c93ec9e656cfe9 183 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 2 179 38.453 T 22-04-2016 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS08345 8674c482c1a7d1a460c93ec9e656cfe9 183 PANTHER PTHR11994 1 178 1.3E-77 T 22-04-2016 L21SP4_RS08345 8674c482c1a7d1a460c93ec9e656cfe9 183 Pfam PF00281 Ribosomal protein L5 25 80 9.3E-21 T 22-04-2016 IPR031310 Ribosomal protein L5, N-terminal L21SP4_RS08345 8674c482c1a7d1a460c93ec9e656cfe9 183 Gene3D G3DSA:3.30.1440.10 3 178 7.1E-68 T 22-04-2016 IPR022803 Ribosomal protein L5 domain L21SP4_RS08345 8674c482c1a7d1a460c93ec9e656cfe9 183 ProSitePatterns PS00358 Ribosomal protein L5 signature. 57 73 - T 22-04-2016 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS03090 aa5157aedec1927e80a8ef74910802fd 397 SUPERFAMILY SSF53756 13 394 5.89E-78 T 22-04-2016 L21SP4_RS03090 aa5157aedec1927e80a8ef74910802fd 397 Pfam PF13439 Glycosyltransferase Family 4 18 187 2.3E-16 T 22-04-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain L21SP4_RS03090 aa5157aedec1927e80a8ef74910802fd 397 PANTHER PTHR12526 9 46 8.6E-63 T 22-04-2016 L21SP4_RS03090 aa5157aedec1927e80a8ef74910802fd 397 PANTHER PTHR12526 63 395 8.6E-63 T 22-04-2016 L21SP4_RS03090 aa5157aedec1927e80a8ef74910802fd 397 Pfam PF00534 Glycosyl transferases group 1 198 364 1.2E-32 T 22-04-2016 IPR001296 Glycosyl transferase, family 1 L21SP4_RS03090 aa5157aedec1927e80a8ef74910802fd 397 Gene3D G3DSA:3.40.50.2000 169 362 3.4E-32 T 22-04-2016 L21SP4_RS08310 f5653575e337bfec4cf42a88abfc8191 446 PANTHER PTHR10906 1 446 4.9E-190 T 22-04-2016 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: REACT_15380 L21SP4_RS08310 f5653575e337bfec4cf42a88abfc8191 446 PANTHER PTHR10906:SF2 1 446 4.9E-190 T 22-04-2016 L21SP4_RS08310 f5653575e337bfec4cf42a88abfc8191 446 SUPERFAMILY SSF103491 1 428 3.14E-120 T 22-04-2016 IPR023201 SecY subunit domain L21SP4_RS08310 f5653575e337bfec4cf42a88abfc8191 446 Pfam PF00344 SecY translocase 78 421 1.1E-114 T 22-04-2016 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: REACT_15380 L21SP4_RS08310 f5653575e337bfec4cf42a88abfc8191 446 PIRSF PIRSF004557 1 445 2.8E-120 T 22-04-2016 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: REACT_15380 L21SP4_RS08310 f5653575e337bfec4cf42a88abfc8191 446 Gene3D G3DSA:1.10.3370.10 1 441 1.1E-152 T 22-04-2016 IPR023201 SecY subunit domain L21SP4_RS08310 f5653575e337bfec4cf42a88abfc8191 446 Hamap MF_01465 Protein translocase subunit SecY [secY]. 5 437 29.731 T 22-04-2016 IPR026593 Protein translocase subunit SecY L21SP4_RS08310 f5653575e337bfec4cf42a88abfc8191 446 ProSitePatterns PS00756 Protein secY signature 2. 177 194 - T 22-04-2016 IPR030659 SecY conserved site L21SP4_RS08310 f5653575e337bfec4cf42a88abfc8191 446 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 15 431 1.7E-118 T 22-04-2016 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: REACT_15380 L21SP4_RS08310 f5653575e337bfec4cf42a88abfc8191 446 PRINTS PR00303 Preprotein translocase SecY subunit signature 276 295 8.9E-86 T 22-04-2016 L21SP4_RS08310 f5653575e337bfec4cf42a88abfc8191 446 PRINTS PR00303 Preprotein translocase SecY subunit signature 158 183 8.9E-86 T 22-04-2016 L21SP4_RS08310 f5653575e337bfec4cf42a88abfc8191 446 PRINTS PR00303 Preprotein translocase SecY subunit signature 184 207 8.9E-86 T 22-04-2016 L21SP4_RS08310 f5653575e337bfec4cf42a88abfc8191 446 PRINTS PR00303 Preprotein translocase SecY subunit signature 74 94 8.9E-86 T 22-04-2016 L21SP4_RS08310 f5653575e337bfec4cf42a88abfc8191 446 PRINTS PR00303 Preprotein translocase SecY subunit signature 406 424 8.9E-86 T 22-04-2016 L21SP4_RS08310 f5653575e337bfec4cf42a88abfc8191 446 PRINTS PR00303 Preprotein translocase SecY subunit signature 370 388 8.9E-86 T 22-04-2016 L21SP4_RS08310 f5653575e337bfec4cf42a88abfc8191 446 PRINTS PR00303 Preprotein translocase SecY subunit signature 18 36 8.9E-86 T 22-04-2016 L21SP4_RS08310 f5653575e337bfec4cf42a88abfc8191 446 PRINTS PR00303 Preprotein translocase SecY subunit signature 115 138 8.9E-86 T 22-04-2016 L21SP4_RS08310 f5653575e337bfec4cf42a88abfc8191 446 PRINTS PR00303 Preprotein translocase SecY subunit signature 315 337 8.9E-86 T 22-04-2016 L21SP4_RS06735 eed4ef1146a8d60b7c856444e29d2768 421 Gene3D G3DSA:3.90.350.10 94 330 3.1E-17 T 22-04-2016 IPR014736 Transposase, Tn5-like, core L21SP4_RS06735 eed4ef1146a8d60b7c856444e29d2768 421 Pfam PF01609 Transposase DDE domain 98 348 6.8E-8 T 22-04-2016 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 L21SP4_RS06735 eed4ef1146a8d60b7c856444e29d2768 421 SUPERFAMILY SSF53098 89 354 4.48E-19 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS02105 3a618fc85e17538a2254e2dd3615421f 384 PANTHER PTHR10909:SF305 2 381 4.8E-176 T 22-04-2016 L21SP4_RS02105 3a618fc85e17538a2254e2dd3615421f 384 SUPERFAMILY SSF56645 2 239 1.57E-85 T 22-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 L21SP4_RS02105 3a618fc85e17538a2254e2dd3615421f 384 Gene3D G3DSA:1.20.140.10 217 382 2.3E-71 T 22-04-2016 L21SP4_RS02105 3a618fc85e17538a2254e2dd3615421f 384 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 228 376 7.0E-51 T 22-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 L21SP4_RS02105 3a618fc85e17538a2254e2dd3615421f 384 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 117 1.1E-30 T 22-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 L21SP4_RS02105 3a618fc85e17538a2254e2dd3615421f 384 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 123 135 - T 22-04-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 L21SP4_RS02105 3a618fc85e17538a2254e2dd3615421f 384 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 121 216 4.6E-31 T 22-04-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 L21SP4_RS02105 3a618fc85e17538a2254e2dd3615421f 384 Gene3D G3DSA:1.10.540.10 3 118 8.5E-38 T 22-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 L21SP4_RS02105 3a618fc85e17538a2254e2dd3615421f 384 PANTHER PTHR10909 2 381 4.8E-176 T 22-04-2016 L21SP4_RS02105 3a618fc85e17538a2254e2dd3615421f 384 Gene3D G3DSA:2.40.110.10 120 216 1.6E-43 T 22-04-2016 L21SP4_RS02105 3a618fc85e17538a2254e2dd3615421f 384 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 336 355 - T 22-04-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 L21SP4_RS02105 3a618fc85e17538a2254e2dd3615421f 384 SUPERFAMILY SSF47203 227 381 2.26E-57 T 22-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 L21SP4_RS06795 7e40324251f5841db19cb794185a75b5 113 PANTHER PTHR30115 1 112 1.8E-53 T 22-04-2016 L21SP4_RS06795 7e40324251f5841db19cb794185a75b5 113 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 4.5E-35 T 22-04-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 L21SP4_RS06795 7e40324251f5841db19cb794185a75b5 113 PANTHER PTHR30115:SF8 1 112 1.8E-53 T 22-04-2016 L21SP4_RS06795 7e40324251f5841db19cb794185a75b5 113 SUPERFAMILY SSF54913 1 111 1.27E-37 T 22-04-2016 IPR011322 Nitrogen regulatory PII-like, alpha/beta L21SP4_RS06795 7e40324251f5841db19cb794185a75b5 113 SMART SM00938 4 105 6.8E-50 T 22-04-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 L21SP4_RS06795 7e40324251f5841db19cb794185a75b5 113 PRINTS PR00340 P-II protein signature 83 103 1.0E-26 T 22-04-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 L21SP4_RS06795 7e40324251f5841db19cb794185a75b5 113 PRINTS PR00340 P-II protein signature 2 17 1.0E-26 T 22-04-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 L21SP4_RS06795 7e40324251f5841db19cb794185a75b5 113 PRINTS PR00340 P-II protein signature 52 75 1.0E-26 T 22-04-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 L21SP4_RS06795 7e40324251f5841db19cb794185a75b5 113 PRINTS PR00340 P-II protein signature 23 41 1.0E-26 T 22-04-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 L21SP4_RS06795 7e40324251f5841db19cb794185a75b5 113 Gene3D G3DSA:3.30.70.120 1 110 5.4E-40 T 22-04-2016 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal L21SP4_RS06795 7e40324251f5841db19cb794185a75b5 113 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 22-04-2016 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 L21SP4_RS10070 e1763b21505e2e759ae5c03f4ca09695 307 Pfam PF01545 Cation efflux family 23 204 2.2E-34 T 22-04-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 L21SP4_RS10070 e1763b21505e2e759ae5c03f4ca09695 307 PANTHER PTHR11562:SF17 3 298 1.2E-77 T 22-04-2016 L21SP4_RS10070 e1763b21505e2e759ae5c03f4ca09695 307 SUPERFAMILY SSF160240 221 291 1.16E-7 T 22-04-2016 L21SP4_RS10070 e1763b21505e2e759ae5c03f4ca09695 307 PANTHER PTHR11562 3 298 1.2E-77 T 22-04-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 L21SP4_RS10070 e1763b21505e2e759ae5c03f4ca09695 307 Gene3D G3DSA:1.20.1510.10 21 207 4.0E-43 T 22-04-2016 IPR027469 Cation efflux protein transmembrane domain L21SP4_RS10070 e1763b21505e2e759ae5c03f4ca09695 307 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 20 291 5.9E-59 T 22-04-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 L21SP4_RS10070 e1763b21505e2e759ae5c03f4ca09695 307 SUPERFAMILY SSF161111 21 211 7.72E-43 T 22-04-2016 L21SP4_RS06980 46eb9567636c7749bb100b3d6a55e1eb 573 PANTHER PTHR33908 1 546 3.9E-48 T 22-04-2016 L21SP4_RS06980 46eb9567636c7749bb100b3d6a55e1eb 573 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 68 231 5.3E-14 T 22-04-2016 L21SP4_RS09970 1521ed14a29399bf8e0708fdd88700fd 598 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 5 138 1.0E-21 T 22-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 L21SP4_RS09970 1521ed14a29399bf8e0708fdd88700fd 598 Gene3D G3DSA:2.40.50.250 478 572 2.9E-35 T 22-04-2016 L21SP4_RS09970 1521ed14a29399bf8e0708fdd88700fd 598 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 43 58 - T 22-04-2016 IPR031157 Tr-type G domain, conserved site L21SP4_RS09970 1521ed14a29399bf8e0708fdd88700fd 598 SUPERFAMILY SSF50447 151 296 9.94E-31 T 22-04-2016 IPR009000 Translation protein, beta-barrel domain L21SP4_RS09970 1521ed14a29399bf8e0708fdd88700fd 598 SUPERFAMILY SSF52540 2 198 6.69E-52 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS09970 1521ed14a29399bf8e0708fdd88700fd 598 PRINTS PR00315 GTP-binding elongation factor signature 6 19 6.0E-13 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 L21SP4_RS09970 1521ed14a29399bf8e0708fdd88700fd 598 PRINTS PR00315 GTP-binding elongation factor signature 70 80 6.0E-13 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 L21SP4_RS09970 1521ed14a29399bf8e0708fdd88700fd 598 PRINTS PR00315 GTP-binding elongation factor signature 122 131 6.0E-13 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 L21SP4_RS09970 1521ed14a29399bf8e0708fdd88700fd 598 PRINTS PR00315 GTP-binding elongation factor signature 50 58 6.0E-13 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 L21SP4_RS09970 1521ed14a29399bf8e0708fdd88700fd 598 SUPERFAMILY SSF54980 395 508 1.68E-24 T 22-04-2016 IPR009022 Elongation factor G, III-V domain L21SP4_RS09970 1521ed14a29399bf8e0708fdd88700fd 598 Gene3D G3DSA:3.40.50.300 2 198 1.2E-57 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS09970 1521ed14a29399bf8e0708fdd88700fd 598 PANTHER PTHR23115 2 588 7.0E-248 T 22-04-2016 L21SP4_RS09970 1521ed14a29399bf8e0708fdd88700fd 598 PANTHER PTHR23115:SF14 2 588 7.0E-248 T 22-04-2016 IPR006298 GTP-binding protein TypA GO:0005525 L21SP4_RS09970 1521ed14a29399bf8e0708fdd88700fd 598 Pfam PF00679 Elongation factor G C-terminus 394 475 1.8E-20 T 22-04-2016 IPR000640 Translation elongation factor EFG, V domain L21SP4_RS09970 1521ed14a29399bf8e0708fdd88700fd 598 Gene3D G3DSA:3.30.70.240 398 475 3.9E-25 T 22-04-2016 IPR000640 Translation elongation factor EFG, V domain L21SP4_RS09970 1521ed14a29399bf8e0708fdd88700fd 598 Pfam PF00009 Elongation factor Tu GTP binding domain 3 178 1.5E-51 T 22-04-2016 L21SP4_RS09970 1521ed14a29399bf8e0708fdd88700fd 598 SUPERFAMILY SSF54980 300 384 1.15E-11 T 22-04-2016 IPR009022 Elongation factor G, III-V domain L21SP4_RS09970 1521ed14a29399bf8e0708fdd88700fd 598 Gene3D G3DSA:2.40.30.10 200 301 7.5E-27 T 22-04-2016 L21SP4_RS09970 1521ed14a29399bf8e0708fdd88700fd 598 Pfam PF03144 Elongation factor Tu domain 2 217 286 2.2E-10 T 22-04-2016 IPR004161 Translation elongation factor EFTu/EF1A, domain 2 GO:0005525 L21SP4_RS09970 1521ed14a29399bf8e0708fdd88700fd 598 Gene3D G3DSA:3.30.70.870 302 397 4.7E-30 T 22-04-2016 L21SP4_RS09970 1521ed14a29399bf8e0708fdd88700fd 598 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 4 594 3.2E-260 T 22-04-2016 IPR006298 GTP-binding protein TypA GO:0005525 L21SP4_RS05690 c71633e527cce3e890fdef6b761bd42a 455 SUPERFAMILY SSF142019 130 309 1.96E-52 T 22-04-2016 L21SP4_RS05690 c71633e527cce3e890fdef6b761bd42a 455 PANTHER PTHR11780:SF1 1 455 2.4E-148 T 22-04-2016 L21SP4_RS05690 c71633e527cce3e890fdef6b761bd42a 455 SUPERFAMILY SSF46548 342 450 5.36E-20 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 L21SP4_RS05690 c71633e527cce3e890fdef6b761bd42a 455 Pfam PF10531 SLBB domain 303 350 1.9E-12 T 22-04-2016 IPR019554 Soluble ligand binding domain L21SP4_RS05690 c71633e527cce3e890fdef6b761bd42a 455 Hamap MF_00461 Electron transport complex subunit RsxC [rsxC]. 1 455 132.677 T 22-04-2016 IPR010208 Electron transport complex, subunit RnfC/RsxC GO:0009055|GO:0016020|GO:0051539 L21SP4_RS05690 c71633e527cce3e890fdef6b761bd42a 455 Pfam PF13237 4Fe-4S dicluster domain 377 431 2.6E-8 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain L21SP4_RS05690 c71633e527cce3e890fdef6b761bd42a 455 Gene3D G3DSA:1.10.1060.10 328 452 2.0E-16 T 22-04-2016 L21SP4_RS05690 c71633e527cce3e890fdef6b761bd42a 455 PANTHER PTHR11780 1 455 2.4E-148 T 22-04-2016 L21SP4_RS05690 c71633e527cce3e890fdef6b761bd42a 455 TIGRFAM TIGR01945 rnfC: electron transport complex, RnfABCDGE type, C subunit 14 450 2.0E-147 T 22-04-2016 IPR010208 Electron transport complex, subunit RnfC/RsxC GO:0009055|GO:0016020|GO:0051539 L21SP4_RS05690 c71633e527cce3e890fdef6b761bd42a 455 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 381 392 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site L21SP4_RS05690 c71633e527cce3e890fdef6b761bd42a 455 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 420 431 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site L21SP4_RS05690 c71633e527cce3e890fdef6b761bd42a 455 Pfam PF13375 RnfC Barrel sandwich hybrid domain 13 108 4.7E-23 T 22-04-2016 IPR026902 RnfC Barrel sandwich hybrid domain L21SP4_RS05690 c71633e527cce3e890fdef6b761bd42a 455 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 144 288 1.1E-48 T 22-04-2016 IPR011538 NADH-ubiquinone oxidoreductase 51 kDa subunit, FMN-binding domain L21SP4_RS08125 c95def592d6d978b35abd824aaa0463c 256 PANTHER PTHR10264 4 244 1.9E-107 T 22-04-2016 IPR001972 Stomatin family GO:0016020 L21SP4_RS08125 c95def592d6d978b35abd824aaa0463c 256 PRINTS PR00721 Stomatin signature 170 191 4.4E-65 T 22-04-2016 IPR001972 Stomatin family GO:0016020 L21SP4_RS08125 c95def592d6d978b35abd824aaa0463c 256 PRINTS PR00721 Stomatin signature 24 46 4.4E-65 T 22-04-2016 IPR001972 Stomatin family GO:0016020 L21SP4_RS08125 c95def592d6d978b35abd824aaa0463c 256 PRINTS PR00721 Stomatin signature 107 124 4.4E-65 T 22-04-2016 IPR001972 Stomatin family GO:0016020 L21SP4_RS08125 c95def592d6d978b35abd824aaa0463c 256 PRINTS PR00721 Stomatin signature 72 93 4.4E-65 T 22-04-2016 IPR001972 Stomatin family GO:0016020 L21SP4_RS08125 c95def592d6d978b35abd824aaa0463c 256 PRINTS PR00721 Stomatin signature 127 150 4.4E-65 T 22-04-2016 IPR001972 Stomatin family GO:0016020 L21SP4_RS08125 c95def592d6d978b35abd824aaa0463c 256 PRINTS PR00721 Stomatin signature 151 169 4.4E-65 T 22-04-2016 IPR001972 Stomatin family GO:0016020 L21SP4_RS08125 c95def592d6d978b35abd824aaa0463c 256 PRINTS PR00721 Stomatin signature 195 218 4.4E-65 T 22-04-2016 IPR001972 Stomatin family GO:0016020 L21SP4_RS08125 c95def592d6d978b35abd824aaa0463c 256 SUPERFAMILY SSF117892 50 182 1.44E-41 T 22-04-2016 IPR001107 Band 7 domain L21SP4_RS08125 c95def592d6d978b35abd824aaa0463c 256 PANTHER PTHR10264:SF60 4 244 1.9E-107 T 22-04-2016 L21SP4_RS08125 c95def592d6d978b35abd824aaa0463c 256 SMART SM00244 17 175 8.7E-57 T 22-04-2016 IPR001107 Band 7 domain L21SP4_RS08125 c95def592d6d978b35abd824aaa0463c 256 Pfam PF01145 SPFH domain / Band 7 family 24 191 5.9E-29 T 22-04-2016 IPR001107 Band 7 domain L21SP4_RS04735 774216f69f7a50990d79f4e07081ceb6 525 Gene3D G3DSA:3.30.1330.90 320 449 5.8E-8 T 22-04-2016 IPR029009 Allosteric substrate binding domain L21SP4_RS04735 774216f69f7a50990d79f4e07081ceb6 525 Pfam PF01842 ACT domain 453 482 1.0E-7 T 22-04-2016 IPR002912 ACT domain GO:0008152|GO:0016597 L21SP4_RS04735 774216f69f7a50990d79f4e07081ceb6 525 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 5 310 3.1E-26 T 22-04-2016 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 L21SP4_RS04735 774216f69f7a50990d79f4e07081ceb6 525 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 106 276 4.5E-45 T 22-04-2016 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 L21SP4_RS04735 774216f69f7a50990d79f4e07081ceb6 525 SUPERFAMILY SSF52283 1 134 1.21E-32 T 22-04-2016 L21SP4_RS04735 774216f69f7a50990d79f4e07081ceb6 525 PANTHER PTHR10996:SF20 1 350 2.6E-101 T 22-04-2016 L21SP4_RS04735 774216f69f7a50990d79f4e07081ceb6 525 Gene3D G3DSA:3.40.50.720 107 279 4.8E-49 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS04735 774216f69f7a50990d79f4e07081ceb6 525 SUPERFAMILY SSF55021 449 516 3.17E-12 T 22-04-2016 L21SP4_RS04735 774216f69f7a50990d79f4e07081ceb6 525 SUPERFAMILY SSF143548 321 443 1.46E-7 T 22-04-2016 IPR029009 Allosteric substrate binding domain L21SP4_RS04735 774216f69f7a50990d79f4e07081ceb6 525 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 143 170 - T 22-04-2016 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 L21SP4_RS04735 774216f69f7a50990d79f4e07081ceb6 525 SUPERFAMILY SSF51735 97 271 1.98E-44 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS04735 774216f69f7a50990d79f4e07081ceb6 525 PANTHER PTHR10996 1 350 2.6E-101 T 22-04-2016 L21SP4_RS04735 774216f69f7a50990d79f4e07081ceb6 525 Gene3D G3DSA:3.30.70.260 450 512 7.2E-12 T 22-04-2016 L21SP4_RS04735 774216f69f7a50990d79f4e07081ceb6 525 Gene3D G3DSA:3.40.50.720 2 106 4.4E-32 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS05385 03f1aa772f862c5462561d92d3071565 124 PANTHER PTHR12589 10 120 5.5E-38 T 22-04-2016 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein L21SP4_RS05385 03f1aa772f862c5462561d92d3071565 124 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 6 119 6.2E-34 T 22-04-2016 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein L21SP4_RS05385 03f1aa772f862c5462561d92d3071565 124 Gene3D G3DSA:3.30.479.10 3 120 2.1E-35 T 22-04-2016 L21SP4_RS05385 03f1aa772f862c5462561d92d3071565 124 TIGRFAM TIGR03367 queuosine_QueD: queuosine biosynthesis protein QueD 6 96 5.3E-30 T 22-04-2016 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein L21SP4_RS05385 03f1aa772f862c5462561d92d3071565 124 PIRSF PIRSF006113 1 121 5.2E-40 T 22-04-2016 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein L21SP4_RS05385 03f1aa772f862c5462561d92d3071565 124 SUPERFAMILY SSF55620 3 120 2.67E-36 T 22-04-2016 L21SP4_RS09415 08fa0458f722ca5636e069410524ec16 473 Gene3D G3DSA:3.30.1120.10 415 471 8.3E-11 T 22-04-2016 L21SP4_RS09415 08fa0458f722ca5636e069410524ec16 473 PANTHER PTHR10342 16 473 7.5E-142 T 22-04-2016 L21SP4_RS09415 08fa0458f722ca5636e069410524ec16 473 SUPERFAMILY SSF53649 43 471 3.05E-117 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS09415 08fa0458f722ca5636e069410524ec16 473 ProSitePatterns PS00149 Sulfatases signature 2. 134 145 - T 22-04-2016 IPR024607 Sulfatase, conserved site L21SP4_RS09415 08fa0458f722ca5636e069410524ec16 473 Pfam PF16347 Domain of unknown function (DUF4976) 384 471 8.3E-9 T 22-04-2016 IPR032506 Domain of unknown function DUF4976 L21SP4_RS09415 08fa0458f722ca5636e069410524ec16 473 PANTHER PTHR10342:SF207 16 473 7.5E-142 T 22-04-2016 L21SP4_RS09415 08fa0458f722ca5636e069410524ec16 473 Pfam PF00884 Sulfatase 44 379 4.0E-61 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS09415 08fa0458f722ca5636e069410524ec16 473 Gene3D G3DSA:3.40.720.10 42 398 1.1E-99 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS07695 17bfd90e3a37b05c6053e0be2ec8be7d 431 SUPERFAMILY SSF52540 33 248 2.34E-19 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS07695 17bfd90e3a37b05c6053e0be2ec8be7d 431 PANTHER PTHR33295:SF6 12 355 1.2E-102 T 22-04-2016 L21SP4_RS07695 17bfd90e3a37b05c6053e0be2ec8be7d 431 PANTHER PTHR33295 12 355 1.2E-102 T 22-04-2016 L21SP4_RS07695 17bfd90e3a37b05c6053e0be2ec8be7d 431 Gene3D G3DSA:3.40.50.300 33 157 4.5E-8 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS07695 17bfd90e3a37b05c6053e0be2ec8be7d 431 Pfam PF13173 AAA domain 33 168 8.9E-35 T 22-04-2016 L21SP4_RS07695 17bfd90e3a37b05c6053e0be2ec8be7d 431 Pfam PF13635 Domain of unknown function (DUF4143) 225 356 1.3E-6 T 22-04-2016 IPR025420 Domain of unknown function DUF4143 L21SP4_RS04235 bf7169b91cc144bf7acdb8bf9c7b6514 426 Pfam PF16360 GTP-binding GTPase Middle Region 121 199 6.2E-32 T 22-04-2016 IPR032305 GTP-binding protein, middle domain L21SP4_RS04235 bf7169b91cc144bf7acdb8bf9c7b6514 426 Pfam PF13167 GTP-binding GTPase N-terminal 32 119 9.7E-29 T 22-04-2016 IPR025121 GTPase HflX, N-terminal L21SP4_RS04235 bf7169b91cc144bf7acdb8bf9c7b6514 426 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 274 292 2.4E-7 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 L21SP4_RS04235 bf7169b91cc144bf7acdb8bf9c7b6514 426 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 207 227 2.4E-7 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 L21SP4_RS04235 bf7169b91cc144bf7acdb8bf9c7b6514 426 SUPERFAMILY SSF52540 207 376 9.57E-41 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS04235 bf7169b91cc144bf7acdb8bf9c7b6514 426 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 14 366 9.0E-142 T 22-04-2016 IPR016496 GTPase HflX GO:0005525 L21SP4_RS04235 bf7169b91cc144bf7acdb8bf9c7b6514 426 Hamap MF_00900 GTPase HflX [hflX]. 34 396 48.103 T 22-04-2016 IPR016496 GTPase HflX GO:0005525 L21SP4_RS04235 bf7169b91cc144bf7acdb8bf9c7b6514 426 PANTHER PTHR10229 9 422 1.3E-166 T 22-04-2016 IPR016496 GTPase HflX GO:0005525 L21SP4_RS04235 bf7169b91cc144bf7acdb8bf9c7b6514 426 PANTHER PTHR10229:SF0 9 422 1.3E-166 T 22-04-2016 L21SP4_RS04235 bf7169b91cc144bf7acdb8bf9c7b6514 426 PIRSF PIRSF006809 6 425 9.6E-153 T 22-04-2016 IPR016496 GTPase HflX GO:0005525 L21SP4_RS04235 bf7169b91cc144bf7acdb8bf9c7b6514 426 Pfam PF01926 50S ribosome-binding GTPase 207 325 1.7E-20 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 L21SP4_RS04235 bf7169b91cc144bf7acdb8bf9c7b6514 426 Gene3D G3DSA:3.40.50.300 207 368 4.9E-34 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS09080 97fb73760895d419b5876410f11d5622 97 SUPERFAMILY SSF55021 3 81 2.67E-23 T 22-04-2016 L21SP4_RS09080 97fb73760895d419b5876410f11d5622 97 TIGRFAM TIGR03959 hyd_TM1266: putative iron-only hydrogenase system regulator 4 79 3.8E-29 T 22-04-2016 IPR023860 [FeFe]-hydrogenase system regulator TM1266 L21SP4_RS09080 97fb73760895d419b5876410f11d5622 97 Gene3D G3DSA:3.30.70.1150 1 82 8.3E-31 T 22-04-2016 L21SP4_RS07370 adc1d90d7c4d43844fd30731d3b80ecc 683 SUPERFAMILY SSF52540 509 597 5.76E-5 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS07370 adc1d90d7c4d43844fd30731d3b80ecc 683 SUPERFAMILY SSF52540 628 653 5.76E-5 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS07370 adc1d90d7c4d43844fd30731d3b80ecc 683 PANTHER PTHR11472 23 671 1.1E-153 T 22-04-2016 L21SP4_RS07370 adc1d90d7c4d43844fd30731d3b80ecc 683 Pfam PF13307 Helicase C-terminal domain 510 670 3.9E-30 T 22-04-2016 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 L21SP4_RS07370 adc1d90d7c4d43844fd30731d3b80ecc 683 Pfam PF00270 DEAD/DEAH box helicase 66 120 5.0E-4 T 22-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 L21SP4_RS07370 adc1d90d7c4d43844fd30731d3b80ecc 683 SMART SM00491 525 658 1.8E-21 T 22-04-2016 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 L21SP4_RS07370 adc1d90d7c4d43844fd30731d3b80ecc 683 PANTHER PTHR11472:SF37 23 671 1.1E-153 T 22-04-2016 L21SP4_RS07370 adc1d90d7c4d43844fd30731d3b80ecc 683 Gene3D G3DSA:3.40.50.300 54 155 3.6E-18 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS07370 adc1d90d7c4d43844fd30731d3b80ecc 683 Gene3D G3DSA:3.40.50.300 227 274 3.6E-18 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS07370 adc1d90d7c4d43844fd30731d3b80ecc 683 SUPERFAMILY SSF52540 617 653 5.45E-21 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS07370 adc1d90d7c4d43844fd30731d3b80ecc 683 SUPERFAMILY SSF52540 224 280 5.45E-21 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS07370 adc1d90d7c4d43844fd30731d3b80ecc 683 SUPERFAMILY SSF52540 49 147 5.45E-21 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS01090 cd07a3a840bb79f1394e388d49657fe8 399 Gene3D G3DSA:3.40.50.2300 113 279 6.6E-29 T 22-04-2016 L21SP4_RS01090 cd07a3a840bb79f1394e388d49657fe8 399 SMART SM00342 302 385 9.1E-18 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP4_RS01090 cd07a3a840bb79f1394e388d49657fe8 399 Pfam PF13377 Periplasmic binding protein-like domain 113 278 6.5E-29 T 22-04-2016 L21SP4_RS01090 cd07a3a840bb79f1394e388d49657fe8 399 Gene3D G3DSA:1.10.10.60 283 340 1.6E-10 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS01090 cd07a3a840bb79f1394e388d49657fe8 399 Gene3D G3DSA:1.10.10.60 341 390 2.6E-13 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS01090 cd07a3a840bb79f1394e388d49657fe8 399 Pfam PF12833 Helix-turn-helix domain 309 387 3.5E-19 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP4_RS01090 cd07a3a840bb79f1394e388d49657fe8 399 Gene3D G3DSA:3.40.50.2300 56 112 6.8E-5 T 22-04-2016 L21SP4_RS01090 cd07a3a840bb79f1394e388d49657fe8 399 SUPERFAMILY SSF53822 56 298 5.26E-34 T 22-04-2016 IPR028082 Periplasmic binding protein-like I L21SP4_RS01090 cd07a3a840bb79f1394e388d49657fe8 399 PANTHER PTHR30146:SF24 1 321 8.8E-49 T 22-04-2016 L21SP4_RS01090 cd07a3a840bb79f1394e388d49657fe8 399 SUPERFAMILY SSF46689 338 389 3.09E-9 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS01090 cd07a3a840bb79f1394e388d49657fe8 399 PANTHER PTHR30146 1 321 8.8E-49 T 22-04-2016 L21SP4_RS01090 cd07a3a840bb79f1394e388d49657fe8 399 SUPERFAMILY SSF46689 285 336 3.23E-7 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS10905 d5fbda76d41239e243daa27cf4755ec3 332 Gene3D G3DSA:4.10.1080.10 122 163 9.3E-5 T 22-04-2016 IPR028974 TSP type-3 repeat GO:0005509 L21SP4_RS02975 b269ea2fd32b339622eeb348b1e0d848 212 PANTHER PTHR11935 1 208 1.9E-50 T 22-04-2016 L21SP4_RS02975 b269ea2fd32b339622eeb348b1e0d848 212 SMART SM00849 12 190 3.0E-35 T 22-04-2016 IPR001279 Metallo-beta-lactamase L21SP4_RS02975 b269ea2fd32b339622eeb348b1e0d848 212 Gene3D G3DSA:3.60.15.10 8 208 2.1E-50 T 22-04-2016 IPR001279 Metallo-beta-lactamase L21SP4_RS02975 b269ea2fd32b339622eeb348b1e0d848 212 Pfam PF00753 Metallo-beta-lactamase superfamily 9 178 1.8E-29 T 22-04-2016 IPR001279 Metallo-beta-lactamase L21SP4_RS02975 b269ea2fd32b339622eeb348b1e0d848 212 SUPERFAMILY SSF56281 1 207 3.8E-50 T 22-04-2016 IPR001279 Metallo-beta-lactamase L21SP4_RS00155 937f6072456affa7da29432237448e9a 314 SUPERFAMILY SSF56925 186 230 4.45E-8 T 22-04-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 L21SP4_RS00155 937f6072456affa7da29432237448e9a 314 SUPERFAMILY SSF56925 259 314 4.45E-8 T 22-04-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 L21SP4_RS00155 937f6072456affa7da29432237448e9a 314 SUPERFAMILY SSF56925 93 154 4.45E-8 T 22-04-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 L21SP4_RS00155 937f6072456affa7da29432237448e9a 314 Gene3D G3DSA:2.40.160.20 95 291 4.8E-6 T 22-04-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 L21SP4_RS00155 937f6072456affa7da29432237448e9a 314 Pfam PF04338 Protein of unknown function, DUF481 135 311 1.2E-16 T 22-04-2016 IPR007433 Protein of unknown function DUF481 L21SP4_RS04180 a876334e6be34f1064234f8411ac54bf 205 Hamap MF_00942 Endonuclease III [nth]. 1 198 30.964 T 22-04-2016 IPR005759 Endonuclease III GO:0003906|GO:0006284 L21SP4_RS04180 a876334e6be34f1064234f8411ac54bf 205 Gene3D G3DSA:1.10.1670.10 112 192 1.9E-28 T 22-04-2016 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal L21SP4_RS04180 a876334e6be34f1064234f8411ac54bf 205 SUPERFAMILY SSF48150 2 197 9.89E-61 T 22-04-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 L21SP4_RS04180 a876334e6be34f1064234f8411ac54bf 205 PANTHER PTHR10359:SF18 2 192 4.4E-69 T 22-04-2016 L21SP4_RS04180 a876334e6be34f1064234f8411ac54bf 205 SMART SM00478 27 174 5.7E-51 T 22-04-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: REACT_216 L21SP4_RS04180 a876334e6be34f1064234f8411ac54bf 205 PANTHER PTHR10359 2 192 4.4E-69 T 22-04-2016 L21SP4_RS04180 a876334e6be34f1064234f8411ac54bf 205 PIRSF PIRSF001435 4 199 5.3E-45 T 22-04-2016 IPR005759 Endonuclease III GO:0003906|GO:0006284 L21SP4_RS04180 a876334e6be34f1064234f8411ac54bf 205 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 23 157 9.2E-22 T 22-04-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: REACT_216 L21SP4_RS04180 a876334e6be34f1064234f8411ac54bf 205 Pfam PF00633 Helix-hairpin-helix motif 88 116 9.2E-6 T 22-04-2016 IPR000445 Helix-hairpin-helix motif GO:0003677 L21SP4_RS04180 a876334e6be34f1064234f8411ac54bf 205 ProSitePatterns PS01155 Endonuclease III family signature. 91 120 - T 22-04-2016 IPR004036 Endonuclease III-like, conserved site-2 Reactome: REACT_216 L21SP4_RS04180 a876334e6be34f1064234f8411ac54bf 205 Gene3D G3DSA:1.10.340.30 14 111 3.4E-33 T 22-04-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 L21SP4_RS07330 4ebd4fbc4c7ba728d47aba60c0d589ce 449 Gene3D G3DSA:3.40.390.10 227 240 7.4E-4 T 22-04-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 L21SP4_RS07330 4ebd4fbc4c7ba728d47aba60c0d589ce 449 Gene3D G3DSA:3.40.390.10 59 123 7.4E-4 T 22-04-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 L21SP4_RS07330 4ebd4fbc4c7ba728d47aba60c0d589ce 449 Gene3D G3DSA:3.40.390.10 158 181 7.4E-4 T 22-04-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 L21SP4_RS07330 4ebd4fbc4c7ba728d47aba60c0d589ce 449 SUPERFAMILY SSF55486 155 179 8.35E-6 T 22-04-2016 L21SP4_RS07330 4ebd4fbc4c7ba728d47aba60c0d589ce 449 SUPERFAMILY SSF55486 52 119 8.35E-6 T 22-04-2016 L21SP4_RS07330 4ebd4fbc4c7ba728d47aba60c0d589ce 449 SUPERFAMILY SSF55486 272 283 8.35E-6 T 22-04-2016 L21SP4_RS05715 74663c19a284251ef8630a7eedc60c35 301 Gene3D G3DSA:3.30.70.20 139 173 1.5E-12 T 22-04-2016 L21SP4_RS05715 74663c19a284251ef8630a7eedc60c35 301 SUPERFAMILY SSF54862 128 226 8.17E-17 T 22-04-2016 L21SP4_RS05715 74663c19a284251ef8630a7eedc60c35 301 Pfam PF13459 4Fe-4S single cluster domain 216 263 1.8E-5 T 22-04-2016 L21SP4_RS05715 74663c19a284251ef8630a7eedc60c35 301 TIGRFAM TIGR01944 rnfB: electron transport complex, RnfABCDGE type, B subunit 4 93 8.3E-22 T 22-04-2016 IPR010207 Electron transport complex, RnfB/RsxB GO:0009055|GO:0051536 L21SP4_RS05715 74663c19a284251ef8630a7eedc60c35 301 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 169 180 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site L21SP4_RS05715 74663c19a284251ef8630a7eedc60c35 301 Gene3D G3DSA:3.30.70.20 174 218 1.2E-9 T 22-04-2016 L21SP4_RS05715 74663c19a284251ef8630a7eedc60c35 301 Pfam PF04060 Putative Fe-S cluster 44 76 1.3E-12 T 22-04-2016 IPR007202 4Fe-4S domain GO:0051536 L21SP4_RS05715 74663c19a284251ef8630a7eedc60c35 301 SUPERFAMILY SSF54862 216 265 4.19E-5 T 22-04-2016 L21SP4_RS05715 74663c19a284251ef8630a7eedc60c35 301 Gene3D G3DSA:3.30.70.20 219 264 1.2E-5 T 22-04-2016 L21SP4_RS05715 74663c19a284251ef8630a7eedc60c35 301 Pfam PF00037 4Fe-4S binding domain 163 184 3.1E-9 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain L21SP4_RS10155 e3bfd439e658cf88833a776f2ad3639c 426 SUPERFAMILY SSF54826 4 138 7.78E-57 T 22-04-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 L21SP4_RS10155 e3bfd439e658cf88833a776f2ad3639c 426 SMART SM01192 139 426 4.3E-212 T 22-04-2016 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 L21SP4_RS10155 e3bfd439e658cf88833a776f2ad3639c 426 Hamap MF_00318 Enolase [eno]. 2 418 44.508 T 22-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 L21SP4_RS10155 e3bfd439e658cf88833a776f2ad3639c 426 ProSitePatterns PS00164 Enolase signature. 341 354 - T 22-04-2016 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 L21SP4_RS10155 e3bfd439e658cf88833a776f2ad3639c 426 SMART SM01193 4 134 8.4E-93 T 22-04-2016 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 L21SP4_RS10155 e3bfd439e658cf88833a776f2ad3639c 426 Pfam PF03952 Enolase, N-terminal domain 4 134 5.3E-60 T 22-04-2016 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 L21SP4_RS10155 e3bfd439e658cf88833a776f2ad3639c 426 PIRSF PIRSF001400 1 426 2.9E-186 T 22-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 L21SP4_RS10155 e3bfd439e658cf88833a776f2ad3639c 426 Pfam PF00113 Enolase, C-terminal TIM barrel domain 140 426 2.8E-127 T 22-04-2016 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 L21SP4_RS10155 e3bfd439e658cf88833a776f2ad3639c 426 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 425 2.5E-208 T 22-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 L21SP4_RS10155 e3bfd439e658cf88833a776f2ad3639c 426 Gene3D G3DSA:3.30.390.10 4 126 3.6E-56 T 22-04-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 L21SP4_RS10155 e3bfd439e658cf88833a776f2ad3639c 426 SUPERFAMILY SSF51604 138 425 2.49E-124 T 22-04-2016 IPR029065 Enolase C-terminal domain-like L21SP4_RS10155 e3bfd439e658cf88833a776f2ad3639c 426 PRINTS PR00148 Enolase signature 37 51 4.65E-46 T 22-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 L21SP4_RS10155 e3bfd439e658cf88833a776f2ad3639c 426 PRINTS PR00148 Enolase signature 107 123 4.65E-46 T 22-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 L21SP4_RS10155 e3bfd439e658cf88833a776f2ad3639c 426 PRINTS PR00148 Enolase signature 318 329 4.65E-46 T 22-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 L21SP4_RS10155 e3bfd439e658cf88833a776f2ad3639c 426 PRINTS PR00148 Enolase signature 370 387 4.65E-46 T 22-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 L21SP4_RS10155 e3bfd439e658cf88833a776f2ad3639c 426 PRINTS PR00148 Enolase signature 341 355 4.65E-46 T 22-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 L21SP4_RS10155 e3bfd439e658cf88833a776f2ad3639c 426 PRINTS PR00148 Enolase signature 161 174 4.65E-46 T 22-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 L21SP4_RS10155 e3bfd439e658cf88833a776f2ad3639c 426 PANTHER PTHR11902 1 426 3.8E-257 T 22-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 L21SP4_RS10155 e3bfd439e658cf88833a776f2ad3639c 426 Gene3D G3DSA:3.20.20.120 128 425 4.2E-133 T 22-04-2016 IPR029065 Enolase C-terminal domain-like L21SP4_RS02660 2bf74a74168068783c37217d8d35877a 223 Gene3D G3DSA:1.25.40.10 106 208 1.3E-14 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS02660 2bf74a74168068783c37217d8d35877a 223 Pfam PF09976 Tetratricopeptide repeat-like domain 37 199 3.9E-15 T 22-04-2016 IPR018704 Tetratricopeptide repeat-like domain L21SP4_RS02660 2bf74a74168068783c37217d8d35877a 223 SUPERFAMILY SSF48452 87 202 1.57E-14 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS02520 0b7841af73632246bc56210e25bc5e0f 319 SUPERFAMILY SSF52402 162 306 6.4E-49 T 22-04-2016 L21SP4_RS02520 0b7841af73632246bc56210e25bc5e0f 319 SUPERFAMILY SSF52402 20 108 6.4E-49 T 22-04-2016 L21SP4_RS02520 0b7841af73632246bc56210e25bc5e0f 319 TIGRFAM TIGR00552 nadE: NAD+ synthetase 164 306 1.0E-31 T 22-04-2016 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|UniPathway: UPA00253 L21SP4_RS02520 0b7841af73632246bc56210e25bc5e0f 319 Gene3D G3DSA:3.40.50.620 20 103 2.2E-52 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP4_RS02520 0b7841af73632246bc56210e25bc5e0f 319 Gene3D G3DSA:3.40.50.620 137 306 2.2E-52 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP4_RS02520 0b7841af73632246bc56210e25bc5e0f 319 Pfam PF02540 NAD synthase 21 105 4.0E-15 T 22-04-2016 IPR022310 NAD/GMP synthase L21SP4_RS02520 0b7841af73632246bc56210e25bc5e0f 319 Pfam PF02540 NAD synthase 164 301 1.1E-34 T 22-04-2016 IPR022310 NAD/GMP synthase L21SP4_RS02520 0b7841af73632246bc56210e25bc5e0f 319 PANTHER PTHR23090 147 291 1.3E-41 T 22-04-2016 L21SP4_RS02520 0b7841af73632246bc56210e25bc5e0f 319 PANTHER PTHR23090 20 118 1.3E-41 T 22-04-2016 L21SP4_RS03000 3f861af4a0b13917f3c02aa42481723f 368 PANTHER PTHR12526 1 364 4.7E-52 T 22-04-2016 L21SP4_RS03000 3f861af4a0b13917f3c02aa42481723f 368 Pfam PF13439 Glycosyltransferase Family 4 14 164 9.7E-14 T 22-04-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain L21SP4_RS03000 3f861af4a0b13917f3c02aa42481723f 368 SUPERFAMILY SSF53756 9 364 3.81E-68 T 22-04-2016 L21SP4_RS03000 3f861af4a0b13917f3c02aa42481723f 368 Pfam PF00534 Glycosyl transferases group 1 179 341 9.4E-31 T 22-04-2016 IPR001296 Glycosyl transferase, family 1 L21SP4_RS03000 3f861af4a0b13917f3c02aa42481723f 368 Gene3D G3DSA:3.40.50.2000 177 341 8.0E-30 T 22-04-2016 L21SP4_RS00910 252d22c399356859e9d117eac7b36a82 444 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 192 210 7.0E-20 T 22-04-2016 L21SP4_RS00910 252d22c399356859e9d117eac7b36a82 444 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 7.0E-20 T 22-04-2016 L21SP4_RS00910 252d22c399356859e9d117eac7b36a82 444 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 52 71 7.0E-20 T 22-04-2016 L21SP4_RS00910 252d22c399356859e9d117eac7b36a82 444 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 302 324 7.0E-20 T 22-04-2016 L21SP4_RS00910 252d22c399356859e9d117eac7b36a82 444 Gene3D G3DSA:3.50.50.60 151 350 1.1E-43 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP4_RS00910 252d22c399356859e9d117eac7b36a82 444 Gene3D G3DSA:3.50.50.60 51 150 7.1E-31 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP4_RS00910 252d22c399356859e9d117eac7b36a82 444 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 51 341 5.3E-53 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP4_RS00910 252d22c399356859e9d117eac7b36a82 444 Gene3D G3DSA:2.20.28.10 2 37 1.3E-19 T 22-04-2016 IPR004039 Rubredoxin-type fold L21SP4_RS00910 252d22c399356859e9d117eac7b36a82 444 PANTHER PTHR22912 51 423 8.7E-83 T 22-04-2016 L21SP4_RS00910 252d22c399356859e9d117eac7b36a82 444 SUPERFAMILY SSF57802 2 38 3.2E-11 T 22-04-2016 L21SP4_RS00910 252d22c399356859e9d117eac7b36a82 444 SUPERFAMILY SSF51905 192 350 1.73E-24 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP4_RS00910 252d22c399356859e9d117eac7b36a82 444 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 317 324 8.0E-14 T 22-04-2016 L21SP4_RS00910 252d22c399356859e9d117eac7b36a82 444 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 192 217 8.0E-14 T 22-04-2016 L21SP4_RS00910 252d22c399356859e9d117eac7b36a82 444 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 51 73 8.0E-14 T 22-04-2016 L21SP4_RS00910 252d22c399356859e9d117eac7b36a82 444 PANTHER PTHR22912:SF1 51 423 8.7E-83 T 22-04-2016 L21SP4_RS00910 252d22c399356859e9d117eac7b36a82 444 SUPERFAMILY SSF51905 51 232 3.56E-47 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP4_RS00030 49a0575780fc59a251ba6bb0f8b72b17 426 Hamap MF_00220_B Dihydroorotase [pyrC]. 8 426 38.339 T 22-04-2016 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|UniPathway: UPA00070 L21SP4_RS00030 49a0575780fc59a251ba6bb0f8b72b17 426 SUPERFAMILY SSF51556 60 369 4.81E-97 T 22-04-2016 IPR032466 Metal-dependent hydrolase L21SP4_RS00030 49a0575780fc59a251ba6bb0f8b72b17 426 Pfam PF01979 Amidohydrolase family 56 405 2.6E-23 T 22-04-2016 IPR006680 Amidohydrolase-related GO:0016787 L21SP4_RS00030 49a0575780fc59a251ba6bb0f8b72b17 426 Gene3D G3DSA:2.30.40.10 9 73 2.7E-13 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 L21SP4_RS00030 49a0575780fc59a251ba6bb0f8b72b17 426 PANTHER PTHR11647 7 425 4.3E-149 T 22-04-2016 L21SP4_RS00030 49a0575780fc59a251ba6bb0f8b72b17 426 PANTHER PTHR11647:SF70 7 425 4.3E-149 T 22-04-2016 L21SP4_RS00030 49a0575780fc59a251ba6bb0f8b72b17 426 SUPERFAMILY SSF51338 371 424 6.56E-22 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 L21SP4_RS00030 49a0575780fc59a251ba6bb0f8b72b17 426 SUPERFAMILY SSF51338 8 58 6.56E-22 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 L21SP4_RS00030 49a0575780fc59a251ba6bb0f8b72b17 426 ProSitePatterns PS00482 Dihydroorotase signature 1. 62 70 - T 22-04-2016 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|UniPathway: UPA00070 L21SP4_RS00030 49a0575780fc59a251ba6bb0f8b72b17 426 ProSitePatterns PS00483 Dihydroorotase signature 2. 307 318 - T 22-04-2016 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|UniPathway: UPA00070 L21SP4_RS00030 49a0575780fc59a251ba6bb0f8b72b17 426 Gene3D G3DSA:3.20.20.140 74 411 2.1E-106 T 22-04-2016 L21SP4_RS00030 49a0575780fc59a251ba6bb0f8b72b17 426 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 23 424 3.1E-109 T 22-04-2016 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|UniPathway: UPA00070 L21SP4_RS10300 69a2809cf3e3673e7585e60064577b0b 826 Gene3D G3DSA:3.30.450.20 476 585 2.2E-14 T 22-04-2016 L21SP4_RS10300 69a2809cf3e3673e7585e60064577b0b 826 SUPERFAMILY SSF55781 330 475 1.53E-12 T 22-04-2016 IPR029016 GAF domain-like L21SP4_RS10300 69a2809cf3e3673e7585e60064577b0b 826 SMART SM00091 477 542 0.0061 T 22-04-2016 IPR000014 PAS domain L21SP4_RS10300 69a2809cf3e3673e7585e60064577b0b 826 SUPERFAMILY SSF55785 466 585 1.92E-11 T 22-04-2016 IPR000014 PAS domain L21SP4_RS10300 69a2809cf3e3673e7585e60064577b0b 826 SMART SM00065 328 473 0.0027 T 22-04-2016 IPR003018 GAF domain GO:0005515 L21SP4_RS10300 69a2809cf3e3673e7585e60064577b0b 826 Gene3D G3DSA:3.30.450.40 314 475 1.9E-12 T 22-04-2016 IPR029016 GAF domain-like L21SP4_RS10300 69a2809cf3e3673e7585e60064577b0b 826 Gene3D G3DSA:3.30.565.10 669 816 6.8E-36 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS10300 69a2809cf3e3673e7585e60064577b0b 826 Pfam PF00989 PAS fold 481 584 1.2E-10 T 22-04-2016 IPR013767 PAS fold GO:0006355 L21SP4_RS10300 69a2809cf3e3673e7585e60064577b0b 826 SUPERFAMILY SSF47384 592 667 4.51E-13 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS10300 69a2809cf3e3673e7585e60064577b0b 826 SUPERFAMILY SSF55874 657 816 3.14E-35 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS10300 69a2809cf3e3673e7585e60064577b0b 826 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 710 816 4.4E-18 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS10300 69a2809cf3e3673e7585e60064577b0b 826 SMART SM00387 710 820 4.2E-30 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS10300 69a2809cf3e3673e7585e60064577b0b 826 Gene3D G3DSA:1.10.287.130 597 664 1.4E-11 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS10300 69a2809cf3e3673e7585e60064577b0b 826 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 482 593 1.7E-5 T 22-04-2016 IPR000014 PAS domain L21SP4_RS10300 69a2809cf3e3673e7585e60064577b0b 826 SMART SM00388 602 668 1.0E-10 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS10300 69a2809cf3e3673e7585e60064577b0b 826 Pfam PF00512 His Kinase A (phospho-acceptor) domain 604 666 1.1E-10 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS10300 69a2809cf3e3673e7585e60064577b0b 826 Pfam PF16927 N-terminal 7TM region of histidine kinase 10 234 2.6E-9 T 22-04-2016 IPR031621 Histidine kinase, N-terminal 7TM region L21SP4_RS10300 69a2809cf3e3673e7585e60064577b0b 826 PRINTS PR00344 Bacterial sensor protein C-terminal signature 769 779 4.6E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS10300 69a2809cf3e3673e7585e60064577b0b 826 PRINTS PR00344 Bacterial sensor protein C-terminal signature 751 765 4.6E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS10300 69a2809cf3e3673e7585e60064577b0b 826 PRINTS PR00344 Bacterial sensor protein C-terminal signature 804 817 4.6E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS10300 69a2809cf3e3673e7585e60064577b0b 826 PRINTS PR00344 Bacterial sensor protein C-terminal signature 780 798 4.6E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS10300 69a2809cf3e3673e7585e60064577b0b 826 PANTHER PTHR24423 475 816 1.9E-74 T 22-04-2016 L21SP4_RS10300 69a2809cf3e3673e7585e60064577b0b 826 PANTHER PTHR24423 1 8 1.9E-74 T 22-04-2016 L21SP4_RS10300 69a2809cf3e3673e7585e60064577b0b 826 PANTHER PTHR24423 388 407 1.9E-74 T 22-04-2016 L21SP4_RS06390 f78189f52e8ad5cd0e7438574ef5c9ea 400 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 318 329 - T 22-04-2016 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 L21SP4_RS06390 f78189f52e8ad5cd0e7438574ef5c9ea 400 PANTHER PTHR11780:SF0 17 388 4.6E-150 T 22-04-2016 L21SP4_RS06390 f78189f52e8ad5cd0e7438574ef5c9ea 400 SUPERFAMILY SSF142984 228 298 5.1E-16 T 22-04-2016 L21SP4_RS06390 f78189f52e8ad5cd0e7438574ef5c9ea 400 SMART SM00928 305 350 1.7E-13 T 22-04-2016 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 L21SP4_RS06390 f78189f52e8ad5cd0e7438574ef5c9ea 400 PANTHER PTHR11780 17 388 4.6E-150 T 22-04-2016 L21SP4_RS06390 f78189f52e8ad5cd0e7438574ef5c9ea 400 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 34 205 8.4E-45 T 22-04-2016 IPR011538 NADH-ubiquinone oxidoreductase 51 kDa subunit, FMN-binding domain L21SP4_RS06390 f78189f52e8ad5cd0e7438574ef5c9ea 400 SUPERFAMILY SSF142019 23 226 1.96E-73 T 22-04-2016 L21SP4_RS06390 f78189f52e8ad5cd0e7438574ef5c9ea 400 SUPERFAMILY SSF140490 302 390 1.57E-24 T 22-04-2016 L21SP4_RS06390 f78189f52e8ad5cd0e7438574ef5c9ea 400 Pfam PF10531 SLBB domain 231 263 8.0E-7 T 22-04-2016 IPR019554 Soluble ligand binding domain L21SP4_RS06390 f78189f52e8ad5cd0e7438574ef5c9ea 400 ProSitePatterns PS00644 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. 154 169 - T 22-04-2016 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 L21SP4_RS06390 f78189f52e8ad5cd0e7438574ef5c9ea 400 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 307 387 4.8E-23 T 22-04-2016 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 L21SP4_RS09500 93750494cda68396910fec2ddc724d35 208 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 11 201 6.4E-54 T 22-04-2016 IPR005248 Probable nicotinate-nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|Reactome: REACT_11193|UniPathway: UPA00253 L21SP4_RS09500 93750494cda68396910fec2ddc724d35 208 PANTHER PTHR12039 8 202 7.0E-48 T 22-04-2016 IPR005248 Probable nicotinate-nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|Reactome: REACT_11193|UniPathway: UPA00253 L21SP4_RS09500 93750494cda68396910fec2ddc724d35 208 Gene3D G3DSA:3.40.50.620 7 203 2.7E-62 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP4_RS09500 93750494cda68396910fec2ddc724d35 208 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 7 202 32.103 T 22-04-2016 IPR005248 Probable nicotinate-nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|Reactome: REACT_11193|UniPathway: UPA00253 L21SP4_RS09500 93750494cda68396910fec2ddc724d35 208 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 9 71 7.9E-10 T 22-04-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 L21SP4_RS09500 93750494cda68396910fec2ddc724d35 208 SUPERFAMILY SSF52374 7 202 2.7E-50 T 22-04-2016 L21SP4_RS09500 93750494cda68396910fec2ddc724d35 208 Pfam PF01467 Cytidylyltransferase-like 11 176 8.0E-27 T 22-04-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 L21SP4_RS03225 49aff3d8626fb3fb92c68e224d80b06a 297 SUPERFAMILY SSF53474 5 245 3.9E-32 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold L21SP4_RS03225 49aff3d8626fb3fb92c68e224d80b06a 297 Gene3D G3DSA:3.40.50.1820 26 294 5.1E-44 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold L21SP4_RS03225 49aff3d8626fb3fb92c68e224d80b06a 297 ProSitePatterns PS01173 Lipolytic enzymes "G-D-X-G" family, putative histidine active site. 54 69 - T 22-04-2016 IPR002168 Lipase, GDXG, putative histidine active site GO:0008152|GO:0016787 L21SP4_RS03225 49aff3d8626fb3fb92c68e224d80b06a 297 PANTHER PTHR23024 29 138 9.6E-22 T 22-04-2016 L21SP4_RS03225 49aff3d8626fb3fb92c68e224d80b06a 297 Pfam PF07859 alpha/beta hydrolase fold 55 139 7.8E-15 T 22-04-2016 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 L21SP4_RS07085 c67e6815de5906ada5c7996c08efaead 334 PANTHER PTHR11669 14 170 3.1E-40 T 22-04-2016 L21SP4_RS07085 c67e6815de5906ada5c7996c08efaead 334 Gene3D G3DSA:3.40.50.300 13 169 5.8E-40 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS07085 c67e6815de5906ada5c7996c08efaead 334 Pfam PF13177 DNA polymerase III, delta subunit 23 170 8.1E-39 T 22-04-2016 L21SP4_RS07085 c67e6815de5906ada5c7996c08efaead 334 PANTHER PTHR11669:SF8 14 170 3.1E-40 T 22-04-2016 L21SP4_RS07085 c67e6815de5906ada5c7996c08efaead 334 SUPERFAMILY SSF52540 12 169 5.55E-28 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS05280 b79522d264b41add90326460ca593bed 343 SUPERFAMILY SSF56042 170 340 3.14E-52 T 22-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain L21SP4_RS05280 b79522d264b41add90326460ca593bed 343 PANTHER PTHR10520 9 339 2.3E-151 T 22-04-2016 L21SP4_RS05280 b79522d264b41add90326460ca593bed 343 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 8 335 5.2E-112 T 22-04-2016 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 L21SP4_RS05280 b79522d264b41add90326460ca593bed 343 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 7 342 40.366 T 22-04-2016 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 L21SP4_RS05280 b79522d264b41add90326460ca593bed 343 Gene3D G3DSA:3.30.1330.10 24 166 1.7E-50 T 22-04-2016 IPR016188 PurM-like, N-terminal domain L21SP4_RS05280 b79522d264b41add90326460ca593bed 343 Pfam PF02769 AIR synthase related protein, C-terminal domain 174 339 1.0E-23 T 22-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain L21SP4_RS05280 b79522d264b41add90326460ca593bed 343 Pfam PF00586 AIR synthase related protein, N-terminal domain 55 161 1.7E-15 T 22-04-2016 IPR016188 PurM-like, N-terminal domain L21SP4_RS05280 b79522d264b41add90326460ca593bed 343 SUPERFAMILY SSF55326 8 167 7.92E-41 T 22-04-2016 L21SP4_RS05280 b79522d264b41add90326460ca593bed 343 Gene3D G3DSA:3.90.650.10 170 341 5.0E-61 T 22-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain L21SP4_RS04990 9958b49084d7ebcbc7710ff373f52743 349 Gene3D G3DSA:3.30.70.1140 1 70 4.4E-27 T 22-04-2016 L21SP4_RS04990 9958b49084d7ebcbc7710ff373f52743 349 Gene3D G3DSA:3.20.20.70 94 341 3.1E-99 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP4_RS04990 9958b49084d7ebcbc7710ff373f52743 349 Pfam PF00793 DAHP synthetase I family 97 330 3.0E-80 T 22-04-2016 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674|UniPathway: UPA00030|UniPathway: UPA00357 L21SP4_RS04990 9958b49084d7ebcbc7710ff373f52743 349 TIGRFAM TIGR01361 DAHP_synth_Bsub: 3-deoxy-7-phosphoheptulonate synthase 73 333 2.6E-119 T 22-04-2016 IPR006268 Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2 GO:0009073|GO:0016832 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164|UniPathway: UPA00053 L21SP4_RS04990 9958b49084d7ebcbc7710ff373f52743 349 PANTHER PTHR21057 2 342 6.1E-178 T 22-04-2016 L21SP4_RS04990 9958b49084d7ebcbc7710ff373f52743 349 PANTHER PTHR21057:SF1 2 342 6.1E-178 T 22-04-2016 L21SP4_RS04990 9958b49084d7ebcbc7710ff373f52743 349 SUPERFAMILY SSF51569 1 342 5.04E-116 T 22-04-2016 L21SP4_RS04420 b152bb5bf0d9a2ab62bcb476f749fdcd 1166 Gene3D G3DSA:2.60.120.260 103 235 2.1E-4 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS04420 b152bb5bf0d9a2ab62bcb476f749fdcd 1166 Pfam PF05592 Bacterial alpha-L-rhamnosidase 351 899 1.2E-84 T 22-04-2016 IPR008902 Bacterial alpha-L-rhamnosidase L21SP4_RS04420 b152bb5bf0d9a2ab62bcb476f749fdcd 1166 Gene3D G3DSA:2.60.120.200 1014 1162 6.5E-9 T 22-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP4_RS04420 b152bb5bf0d9a2ab62bcb476f749fdcd 1166 SUPERFAMILY SSF48208 617 906 6.8E-25 T 22-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP4_RS04420 b152bb5bf0d9a2ab62bcb476f749fdcd 1166 PANTHER PTHR33307:SF5 656 951 3.0E-151 T 22-04-2016 L21SP4_RS04420 b152bb5bf0d9a2ab62bcb476f749fdcd 1166 PANTHER PTHR33307:SF5 1 627 3.0E-151 T 22-04-2016 L21SP4_RS04420 b152bb5bf0d9a2ab62bcb476f749fdcd 1166 SUPERFAMILY SSF49899 977 1162 3.36E-6 T 22-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP4_RS04420 b152bb5bf0d9a2ab62bcb476f749fdcd 1166 Gene3D G3DSA:2.60.120.260 342 437 4.7E-5 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS04420 b152bb5bf0d9a2ab62bcb476f749fdcd 1166 Pfam PF08531 Alpha-L-rhamnosidase N-terminal domain 170 326 9.9E-37 T 22-04-2016 IPR013737 Bacterial alpha-L-rhamnosidase N-terminal L21SP4_RS04420 b152bb5bf0d9a2ab62bcb476f749fdcd 1166 PANTHER PTHR33307 656 951 3.0E-151 T 22-04-2016 L21SP4_RS04420 b152bb5bf0d9a2ab62bcb476f749fdcd 1166 PANTHER PTHR33307 1 627 3.0E-151 T 22-04-2016 L21SP4_RS04040 2cac5c84c081f5af835c24f7da3408aa 276 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 6 238 6.8E-36 T 22-04-2016 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 L21SP4_RS04040 2cac5c84c081f5af835c24f7da3408aa 276 SUPERFAMILY SSF55681 2 192 1.49E-43 T 22-04-2016 L21SP4_RS04040 2cac5c84c081f5af835c24f7da3408aa 276 PANTHER PTHR12835 1 238 2.4E-44 T 22-04-2016 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 L21SP4_RS04040 2cac5c84c081f5af835c24f7da3408aa 276 Pfam PF03099 Biotin/lipoate A/B protein ligase family 8 132 5.2E-13 T 22-04-2016 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 L21SP4_RS04040 2cac5c84c081f5af835c24f7da3408aa 276 Gene3D G3DSA:3.30.930.10 2 192 1.3E-49 T 22-04-2016 L21SP4_RS04200 cd1a058a84f2d4d9280a816a7c345048 239 SUPERFAMILY SSF51735 5 234 1.62E-48 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS04200 cd1a058a84f2d4d9280a816a7c345048 239 PANTHER PTHR24322:SF211 151 182 4.7E-37 T 22-04-2016 L21SP4_RS04200 cd1a058a84f2d4d9280a816a7c345048 239 PANTHER PTHR24322:SF211 10 135 4.7E-37 T 22-04-2016 L21SP4_RS04200 cd1a058a84f2d4d9280a816a7c345048 239 Gene3D G3DSA:3.40.50.720 2 234 3.9E-50 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS04200 cd1a058a84f2d4d9280a816a7c345048 239 PANTHER PTHR24322 151 182 4.7E-37 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS04200 cd1a058a84f2d4d9280a816a7c345048 239 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 233 3.7E-31 T 22-04-2016 L21SP4_RS04200 cd1a058a84f2d4d9280a816a7c345048 239 PANTHER PTHR24322 10 135 4.7E-37 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS04200 cd1a058a84f2d4d9280a816a7c345048 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 2.0E-22 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS04200 cd1a058a84f2d4d9280a816a7c345048 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 2.0E-22 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS04200 cd1a058a84f2d4d9280a816a7c345048 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 2.0E-22 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS04200 cd1a058a84f2d4d9280a816a7c345048 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 198 218 2.0E-22 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS04200 cd1a058a84f2d4d9280a816a7c345048 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 2.0E-22 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS01755 99e7ccc45b910e02181bc6c28399944c 442 Pfam PF00884 Sulfatase 29 340 9.0E-74 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS01755 99e7ccc45b910e02181bc6c28399944c 442 PANTHER PTHR10342:SF199 1 429 6.1E-154 T 22-04-2016 L21SP4_RS01755 99e7ccc45b910e02181bc6c28399944c 442 Gene3D G3DSA:3.30.1120.10 377 437 2.3E-21 T 22-04-2016 L21SP4_RS01755 99e7ccc45b910e02181bc6c28399944c 442 PANTHER PTHR10342 1 429 6.1E-154 T 22-04-2016 L21SP4_RS01755 99e7ccc45b910e02181bc6c28399944c 442 SUPERFAMILY SSF53649 27 431 1.74E-124 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS01755 99e7ccc45b910e02181bc6c28399944c 442 ProSitePatterns PS00149 Sulfatases signature 2. 125 135 - T 22-04-2016 IPR024607 Sulfatase, conserved site L21SP4_RS01755 99e7ccc45b910e02181bc6c28399944c 442 Gene3D G3DSA:3.40.720.10 27 376 1.6E-109 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS10390 d8220de6f5130a5cbd897b4e2a09c36e 189 PANTHER PTHR14269 1 146 1.1E-36 T 22-04-2016 L21SP4_RS10390 d8220de6f5130a5cbd897b4e2a09c36e 189 Pfam PF01066 CDP-alcohol phosphatidyltransferase 2 69 6.6E-17 T 22-04-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 L21SP4_RS10390 d8220de6f5130a5cbd897b4e2a09c36e 189 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 47 69 - T 22-04-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 L21SP4_RS10390 d8220de6f5130a5cbd897b4e2a09c36e 189 PIRSF PIRSF000847 1 188 1.1E-45 T 22-04-2016 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|UniPathway: UPA00084 L21SP4_RS10390 d8220de6f5130a5cbd897b4e2a09c36e 189 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 1 180 4.6E-41 T 22-04-2016 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|UniPathway: UPA00084 L21SP4_RS05825 78982ca204cd4bfaf5095c284b4c8325 170 TIGRFAM TIGR00228 ruvC: crossover junction endodeoxyribonuclease RuvC 7 156 1.6E-36 T 22-04-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 L21SP4_RS05825 78982ca204cd4bfaf5095c284b4c8325 170 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 7 154 2.6E-40 T 22-04-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 L21SP4_RS05825 78982ca204cd4bfaf5095c284b4c8325 170 SUPERFAMILY SSF53098 6 157 3.38E-37 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS05825 78982ca204cd4bfaf5095c284b4c8325 170 Gene3D G3DSA:3.30.420.10 5 157 4.2E-48 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS05825 78982ca204cd4bfaf5095c284b4c8325 170 ProSitePatterns PS01321 Crossover junction endodeoxyribonuclease ruvC signature. 117 151 - T 22-04-2016 IPR020563 Crossover junction endodeoxyribonuclease RuvC, magnesium-binding site GO:0008821 L21SP4_RS05825 78982ca204cd4bfaf5095c284b4c8325 170 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 5 157 35.938 T 22-04-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 L21SP4_RS05825 78982ca204cd4bfaf5095c284b4c8325 170 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 8 21 8.3E-29 T 22-04-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 L21SP4_RS05825 78982ca204cd4bfaf5095c284b4c8325 170 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 65 81 8.3E-29 T 22-04-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 L21SP4_RS05825 78982ca204cd4bfaf5095c284b4c8325 170 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 142 154 8.3E-29 T 22-04-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 L21SP4_RS05825 78982ca204cd4bfaf5095c284b4c8325 170 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 111 130 8.3E-29 T 22-04-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 L21SP4_RS05825 78982ca204cd4bfaf5095c284b4c8325 170 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 87 103 8.3E-29 T 22-04-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 L21SP4_RS05825 78982ca204cd4bfaf5095c284b4c8325 170 PANTHER PTHR30194 1 165 3.9E-50 T 22-04-2016 L21SP4_RS02695 91db4720468363a2fcd7d5b33e0c86ed 44 PANTHER PTHR14503 1 44 4.6E-21 T 22-04-2016 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS02695 91db4720468363a2fcd7d5b33e0c86ed 44 ProSitePatterns PS00784 Ribosomal protein L34 signature. 2 21 - T 22-04-2016 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS02695 91db4720468363a2fcd7d5b33e0c86ed 44 Pfam PF00468 Ribosomal protein L34 1 44 6.5E-24 T 22-04-2016 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS02695 91db4720468363a2fcd7d5b33e0c86ed 44 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 1 44 7.8E-23 T 22-04-2016 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS02695 91db4720468363a2fcd7d5b33e0c86ed 44 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 1 26 1.0E-5 T 22-04-2016 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS02695 91db4720468363a2fcd7d5b33e0c86ed 44 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 1 44 16.349 T 22-04-2016 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS02950 1d0d161976af3282ed8b3da00c4b8eb8 541 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 351 373 1.9E-7 T 22-04-2016 L21SP4_RS02950 1d0d161976af3282ed8b3da00c4b8eb8 541 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 1.9E-7 T 22-04-2016 L21SP4_RS02950 1d0d161976af3282ed8b3da00c4b8eb8 541 SUPERFAMILY SSF51905 352 419 1.95E-62 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP4_RS02950 1d0d161976af3282ed8b3da00c4b8eb8 541 SUPERFAMILY SSF51905 2 251 1.95E-62 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP4_RS02950 1d0d161976af3282ed8b3da00c4b8eb8 541 PANTHER PTHR11632:SF27 6 533 1.7E-218 T 22-04-2016 L21SP4_RS02950 1d0d161976af3282ed8b3da00c4b8eb8 541 Pfam PF02910 Fumarate reductase flavoprotein C-term 440 522 2.0E-12 T 22-04-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 L21SP4_RS02950 1d0d161976af3282ed8b3da00c4b8eb8 541 Gene3D G3DSA:1.20.58.100 427 534 5.2E-28 T 22-04-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 L21SP4_RS02950 1d0d161976af3282ed8b3da00c4b8eb8 541 Pfam PF00890 FAD binding domain 7 388 3.4E-91 T 22-04-2016 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain L21SP4_RS02950 1d0d161976af3282ed8b3da00c4b8eb8 541 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 366 373 4.1E-5 T 22-04-2016 L21SP4_RS02950 1d0d161976af3282ed8b3da00c4b8eb8 541 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 4.1E-5 T 22-04-2016 L21SP4_RS02950 1d0d161976af3282ed8b3da00c4b8eb8 541 PIRSF PIRSF000171 1 533 2.4E-32 T 22-04-2016 IPR030664 Succinate dehydrogenase/fumarate reductase, alpha/adenylylsulphate reductase subunit L21SP4_RS02950 1d0d161976af3282ed8b3da00c4b8eb8 541 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 6 518 1.3E-169 T 22-04-2016 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342|UniPathway: UPA00253 L21SP4_RS02950 1d0d161976af3282ed8b3da00c4b8eb8 541 SUPERFAMILY SSF56425 234 348 4.64E-40 T 22-04-2016 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain L21SP4_RS02950 1d0d161976af3282ed8b3da00c4b8eb8 541 Gene3D G3DSA:3.50.50.60 345 408 1.6E-89 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP4_RS02950 1d0d161976af3282ed8b3da00c4b8eb8 541 Gene3D G3DSA:3.50.50.60 2 239 1.6E-89 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP4_RS02950 1d0d161976af3282ed8b3da00c4b8eb8 541 SUPERFAMILY SSF46977 425 523 1.13E-27 T 22-04-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 L21SP4_RS02950 1d0d161976af3282ed8b3da00c4b8eb8 541 PANTHER PTHR11632 6 533 1.7E-218 T 22-04-2016 L21SP4_RS02950 1d0d161976af3282ed8b3da00c4b8eb8 541 Gene3D G3DSA:3.90.700.10 240 344 2.5E-35 T 22-04-2016 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain L21SP4_RS04140 040ee9551fbc7143e49448163a88b8ff 360 SUPERFAMILY SSF53383 1 358 1.67E-110 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase L21SP4_RS04140 040ee9551fbc7143e49448163a88b8ff 360 Pfam PF00266 Aminotransferase class-V 4 348 1.7E-51 T 22-04-2016 IPR000192 Aminotransferase class V domain L21SP4_RS04140 040ee9551fbc7143e49448163a88b8ff 360 PANTHER PTHR21152 3 360 3.5E-170 T 22-04-2016 L21SP4_RS04140 040ee9551fbc7143e49448163a88b8ff 360 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 187 206 - T 22-04-2016 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site L21SP4_RS04140 040ee9551fbc7143e49448163a88b8ff 360 TIGRFAM TIGR01364 serC_1: phosphoserine transaminase 4 359 6.8E-146 T 22-04-2016 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|UniPathway: UPA00135|UniPathway: UPA00244 L21SP4_RS04140 040ee9551fbc7143e49448163a88b8ff 360 PANTHER PTHR21152:SF1 3 360 3.5E-170 T 22-04-2016 L21SP4_RS04140 040ee9551fbc7143e49448163a88b8ff 360 PIRSF PIRSF000525 1 360 1.1E-142 T 22-04-2016 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|UniPathway: UPA00135|UniPathway: UPA00244 L21SP4_RS04140 040ee9551fbc7143e49448163a88b8ff 360 Gene3D G3DSA:3.90.1150.10 258 359 1.2E-41 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 L21SP4_RS04140 040ee9551fbc7143e49448163a88b8ff 360 Gene3D G3DSA:3.40.640.10 17 256 2.2E-95 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 L21SP4_RS04140 040ee9551fbc7143e49448163a88b8ff 360 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 2 359 47.972 T 22-04-2016 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|UniPathway: UPA00135|UniPathway: UPA00244 L21SP4_RS06830 14cc4674fb8e7cbfb0aedfd0a7695794 806 Gene3D G3DSA:2.120.10.90 496 803 8.5E-124 T 22-04-2016 L21SP4_RS06830 14cc4674fb8e7cbfb0aedfd0a7695794 806 PANTHER PTHR10169 6 778 0.0 T 22-04-2016 L21SP4_RS06830 14cc4674fb8e7cbfb0aedfd0a7695794 806 SUPERFAMILY SSF56719 31 487 4.71E-175 T 22-04-2016 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 L21SP4_RS06830 14cc4674fb8e7cbfb0aedfd0a7695794 806 SMART SM00434 12 465 1.6E-270 T 22-04-2016 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 L21SP4_RS06830 14cc4674fb8e7cbfb0aedfd0a7695794 806 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 3 806 28.418 T 22-04-2016 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 L21SP4_RS06830 14cc4674fb8e7cbfb0aedfd0a7695794 806 SUPERFAMILY SSF101904 499 804 3.92E-101 T 22-04-2016 L21SP4_RS06830 14cc4674fb8e7cbfb0aedfd0a7695794 806 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 33 465 3.2E-156 T 22-04-2016 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 L21SP4_RS06830 14cc4674fb8e7cbfb0aedfd0a7695794 806 Gene3D G3DSA:3.90.199.10 334 399 9.2E-116 T 22-04-2016 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 L21SP4_RS06830 14cc4674fb8e7cbfb0aedfd0a7695794 806 Gene3D G3DSA:3.90.199.10 31 236 9.2E-116 T 22-04-2016 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 L21SP4_RS06830 14cc4674fb8e7cbfb0aedfd0a7695794 806 Gene3D G3DSA:3.30.1360.40 237 331 8.0E-37 T 22-04-2016 IPR024946 Arginine repressor C-terminal-like domain L21SP4_RS06830 14cc4674fb8e7cbfb0aedfd0a7695794 806 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 612 654 4.7E-11 T 22-04-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 L21SP4_RS06830 14cc4674fb8e7cbfb0aedfd0a7695794 806 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 555 603 4.6E-6 T 22-04-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 L21SP4_RS06830 14cc4674fb8e7cbfb0aedfd0a7695794 806 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 761 804 3.5E-13 T 22-04-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 L21SP4_RS06830 14cc4674fb8e7cbfb0aedfd0a7695794 806 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 506 548 2.1E-11 T 22-04-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 L21SP4_RS06830 14cc4674fb8e7cbfb0aedfd0a7695794 806 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 709 755 5.9E-15 T 22-04-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 L21SP4_RS06830 14cc4674fb8e7cbfb0aedfd0a7695794 806 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 658 705 1.5E-12 T 22-04-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 L21SP4_RS06830 14cc4674fb8e7cbfb0aedfd0a7695794 806 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 10 803 0.0 T 22-04-2016 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 L21SP4_RS06830 14cc4674fb8e7cbfb0aedfd0a7695794 806 PANTHER PTHR10169:SF48 6 778 0.0 T 22-04-2016 L21SP4_RS09005 d10681a43f95157e83c338d2daea0f8c 364 PANTHER PTHR33529:SF2 3 356 9.7E-53 T 22-04-2016 L21SP4_RS09005 d10681a43f95157e83c338d2daea0f8c 364 PANTHER PTHR33529 3 356 9.7E-53 T 22-04-2016 L21SP4_RS09005 d10681a43f95157e83c338d2daea0f8c 364 Pfam PF03739 Predicted permease YjgP/YjgQ family 3 360 5.1E-67 T 22-04-2016 IPR005495 Permease LptG/LptF-related GO:0016021 L21SP4_RS08780 1bbe2f80c09fc7faa063d294429227ad 303 Pfam PF00535 Glycosyl transferase family 2 2 163 7.8E-29 T 22-04-2016 IPR001173 Glycosyltransferase 2-like L21SP4_RS08780 1bbe2f80c09fc7faa063d294429227ad 303 Gene3D G3DSA:3.90.550.10 2 124 1.2E-18 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases L21SP4_RS08780 1bbe2f80c09fc7faa063d294429227ad 303 SUPERFAMILY SSF53448 2 221 8.19E-33 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases L21SP4_RS08780 1bbe2f80c09fc7faa063d294429227ad 303 PANTHER PTHR10859 1 302 2.4E-132 T 22-04-2016 L21SP4_RS08780 1bbe2f80c09fc7faa063d294429227ad 303 PANTHER PTHR10859:SF86 1 302 2.4E-132 T 22-04-2016 L21SP4_RS10605 8371888f1f8c5d6b1fe4bf2290126efb 265 SUPERFAMILY SSF52540 7 253 9.52E-63 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS10605 8371888f1f8c5d6b1fe4bf2290126efb 265 PANTHER PTHR24220:SF586 9 261 2.1E-110 T 22-04-2016 L21SP4_RS10605 8371888f1f8c5d6b1fe4bf2290126efb 265 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 L21SP4_RS10605 8371888f1f8c5d6b1fe4bf2290126efb 265 Gene3D G3DSA:3.40.50.300 6 255 7.2E-70 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS10605 8371888f1f8c5d6b1fe4bf2290126efb 265 Pfam PF00005 ABC transporter 28 181 1.3E-24 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 L21SP4_RS10605 8371888f1f8c5d6b1fe4bf2290126efb 265 PANTHER PTHR24220 9 261 2.1E-110 T 22-04-2016 L21SP4_RS10605 8371888f1f8c5d6b1fe4bf2290126efb 265 SMART SM00382 36 240 1.1E-13 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS00480 1a9657690f85b48ca2deb03a8fb7ccfc 683 Pfam PF13519 von Willebrand factor type A domain 92 199 3.1E-9 T 22-04-2016 IPR002035 von Willebrand factor, type A L21SP4_RS00480 1a9657690f85b48ca2deb03a8fb7ccfc 683 PANTHER PTHR37464:SF1 6 336 4.7E-37 T 22-04-2016 L21SP4_RS00480 1a9657690f85b48ca2deb03a8fb7ccfc 683 TIGRFAM TIGR02226 two_anch: N-terminal double-transmembrane domain 6 83 1.6E-17 T 22-04-2016 IPR011933 Double transmembrane domain L21SP4_RS00480 1a9657690f85b48ca2deb03a8fb7ccfc 683 SUPERFAMILY SSF53300 91 204 6.99E-7 T 22-04-2016 IPR002035 von Willebrand factor, type A L21SP4_RS00480 1a9657690f85b48ca2deb03a8fb7ccfc 683 Pfam PF07584 Aerotolerance regulator N-terminal 6 79 6.8E-15 T 22-04-2016 IPR024163 Aerotolerance regulator, N-terminal L21SP4_RS00480 1a9657690f85b48ca2deb03a8fb7ccfc 683 PANTHER PTHR37464 6 336 4.7E-37 T 22-04-2016 L21SP4_RS07435 4137b18576d3cec13ea7f4faf3b7b5cd 471 Gene3D G3DSA:3.10.20.70 4 106 5.9E-39 T 22-04-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 L21SP4_RS07435 4137b18576d3cec13ea7f4faf3b7b5cd 471 Gene3D G3DSA:3.30.590.10 107 451 2.1E-134 T 22-04-2016 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 Reactome: REACT_13 L21SP4_RS07435 4137b18576d3cec13ea7f4faf3b7b5cd 471 ProSitePatterns PS00180 Glutamine synthetase signature 1. 51 69 - T 22-04-2016 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 L21SP4_RS07435 4137b18576d3cec13ea7f4faf3b7b5cd 471 Pfam PF00120 Glutamine synthetase, catalytic domain 104 468 8.5E-133 T 22-04-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 L21SP4_RS07435 4137b18576d3cec13ea7f4faf3b7b5cd 471 ProSitePatterns PS00182 Glutamine synthetase class-I adenylation site. 387 399 - T 22-04-2016 IPR001637 Glutamine synthetase class-I, adenylation site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 L21SP4_RS07435 4137b18576d3cec13ea7f4faf3b7b5cd 471 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 259 274 - T 22-04-2016 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 L21SP4_RS07435 4137b18576d3cec13ea7f4faf3b7b5cd 471 SMART SM01230 103 380 6.2E-152 T 22-04-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 L21SP4_RS07435 4137b18576d3cec13ea7f4faf3b7b5cd 471 PANTHER PTHR20852:SF15 5 139 2.2E-254 T 22-04-2016 L21SP4_RS07435 4137b18576d3cec13ea7f4faf3b7b5cd 471 PANTHER PTHR20852:SF15 157 471 2.2E-254 T 22-04-2016 L21SP4_RS07435 4137b18576d3cec13ea7f4faf3b7b5cd 471 PANTHER PTHR20852 5 139 2.2E-254 T 22-04-2016 L21SP4_RS07435 4137b18576d3cec13ea7f4faf3b7b5cd 471 PANTHER PTHR20852 157 471 2.2E-254 T 22-04-2016 L21SP4_RS07435 4137b18576d3cec13ea7f4faf3b7b5cd 471 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 6 470 3.7E-206 T 22-04-2016 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 L21SP4_RS07435 4137b18576d3cec13ea7f4faf3b7b5cd 471 SUPERFAMILY SSF55931 104 470 1.77E-136 T 22-04-2016 L21SP4_RS07435 4137b18576d3cec13ea7f4faf3b7b5cd 471 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 15 96 1.9E-31 T 22-04-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 L21SP4_RS07435 4137b18576d3cec13ea7f4faf3b7b5cd 471 SUPERFAMILY SSF54368 3 100 1.7E-34 T 22-04-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 L21SP4_RS04245 3af3c9d1702d34855f3b45cf065bf53a 265 Gene3D G3DSA:3.40.140.10 124 255 3.5E-38 T 22-04-2016 L21SP4_RS04245 3af3c9d1702d34855f3b45cf065bf53a 265 Pfam PF04002 RadC-like JAB domain 128 252 6.9E-37 T 22-04-2016 IPR025657 RadC-like JAB domain L21SP4_RS04245 3af3c9d1702d34855f3b45cf065bf53a 265 TIGRFAM TIGR00608 radc: DNA repair protein RadC 35 255 9.2E-62 T 22-04-2016 IPR001405 RadC protein L21SP4_RS04245 3af3c9d1702d34855f3b45cf065bf53a 265 Gene3D G3DSA:1.10.150.20 71 110 4.1E-8 T 22-04-2016 L21SP4_RS04245 3af3c9d1702d34855f3b45cf065bf53a 265 PANTHER PTHR30471:SF3 22 255 3.8E-81 T 22-04-2016 L21SP4_RS04245 3af3c9d1702d34855f3b45cf065bf53a 265 PANTHER PTHR30471 22 255 3.8E-81 T 22-04-2016 L21SP4_RS04245 3af3c9d1702d34855f3b45cf065bf53a 265 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 198 203 - T 22-04-2016 IPR020891 Uncharacterised protein family UPF0758, conserved site L21SP4_RS04245 3af3c9d1702d34855f3b45cf065bf53a 265 SUPERFAMILY SSF47781 42 115 1.37E-9 T 22-04-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 L21SP4_RS06285 f7d2015107f97b563787d78c4c8d579d 267 PANTHER PTHR24322 161 192 4.9E-51 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS06285 f7d2015107f97b563787d78c4c8d579d 267 PANTHER PTHR24322 16 145 4.9E-51 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS06285 f7d2015107f97b563787d78c4c8d579d 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 4.0E-9 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS06285 f7d2015107f97b563787d78c4c8d579d 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 88 99 4.0E-9 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS06285 f7d2015107f97b563787d78c4c8d579d 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 4.0E-9 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS06285 f7d2015107f97b563787d78c4c8d579d 267 Gene3D G3DSA:3.40.50.720 8 264 4.2E-80 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS06285 f7d2015107f97b563787d78c4c8d579d 267 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 263 6.0E-60 T 22-04-2016 L21SP4_RS06285 f7d2015107f97b563787d78c4c8d579d 267 SUPERFAMILY SSF51735 10 265 1.51E-77 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS06285 f7d2015107f97b563787d78c4c8d579d 267 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 148 176 - T 22-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 L21SP4_RS06285 f7d2015107f97b563787d78c4c8d579d 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 228 248 1.4E-34 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS06285 f7d2015107f97b563787d78c4c8d579d 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 1.4E-34 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS06285 f7d2015107f97b563787d78c4c8d579d 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 1.4E-34 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS06285 f7d2015107f97b563787d78c4c8d579d 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 1.4E-34 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS06285 f7d2015107f97b563787d78c4c8d579d 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 1.4E-34 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS06285 f7d2015107f97b563787d78c4c8d579d 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 1.4E-34 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS04340 20ebe9ea0f17b90b992bfa51383b775d 109 PANTHER PTHR35866:SF1 4 98 3.5E-22 T 22-04-2016 L21SP4_RS04340 20ebe9ea0f17b90b992bfa51383b775d 109 Pfam PF03692 Putative zinc- or iron-chelating domain 12 102 8.2E-15 T 22-04-2016 IPR005358 Putative zinc- or iron-chelating domain containing protein L21SP4_RS04340 20ebe9ea0f17b90b992bfa51383b775d 109 PANTHER PTHR35866 4 98 3.5E-22 T 22-04-2016 L21SP4_RS05865 ff8705b9932c5a88b93fb291bce43089 268 Pfam PF13469 Sulfotransferase family 76 190 2.8E-18 T 22-04-2016 L21SP4_RS05865 ff8705b9932c5a88b93fb291bce43089 268 Gene3D G3DSA:3.40.50.300 27 265 7.9E-25 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS05865 ff8705b9932c5a88b93fb291bce43089 268 SUPERFAMILY SSF52540 29 262 1.71E-37 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS08725 354769d30f266caca165b1bb55bce7c5 404 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 48 184 1.5E-27 T 22-04-2016 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 L21SP4_RS08725 354769d30f266caca165b1bb55bce7c5 404 SUPERFAMILY SSF52121 45 189 2.49E-35 T 22-04-2016 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 L21SP4_RS08725 354769d30f266caca165b1bb55bce7c5 404 SUPERFAMILY SSF48013 256 386 3.79E-39 T 22-04-2016 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 L21SP4_RS08725 354769d30f266caca165b1bb55bce7c5 404 Gene3D G3DSA:3.40.50.960 45 188 9.2E-37 T 22-04-2016 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 L21SP4_RS08725 354769d30f266caca165b1bb55bce7c5 404 Pfam PF01029 NusB family 259 383 4.4E-34 T 22-04-2016 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 L21SP4_RS08725 354769d30f266caca165b1bb55bce7c5 404 PANTHER PTHR11078 257 401 2.8E-44 T 22-04-2016 IPR011605 NusB antitermination factor GO:0006353 L21SP4_RS08725 354769d30f266caca165b1bb55bce7c5 404 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 47 185 2.7E-31 T 22-04-2016 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 L21SP4_RS08725 354769d30f266caca165b1bb55bce7c5 404 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 43 188 21.358 T 22-04-2016 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 L21SP4_RS08725 354769d30f266caca165b1bb55bce7c5 404 Gene3D G3DSA:1.10.940.10 255 386 8.5E-44 T 22-04-2016 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 L21SP4_RS08725 354769d30f266caca165b1bb55bce7c5 404 Hamap MF_00073 N utilization substance protein B homolog [nusB]. 255 387 22.453 T 22-04-2016 IPR011605 NusB antitermination factor GO:0006353 L21SP4_RS08725 354769d30f266caca165b1bb55bce7c5 404 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 257 385 8.4E-40 T 22-04-2016 IPR011605 NusB antitermination factor GO:0006353 L21SP4_RS10460 0ec5b2deb2275fd519013a232a0c4904 797 Gene3D G3DSA:1.50.10.10 115 241 4.4E-5 T 22-04-2016 IPR012341 Six-hairpin glycosidase GO:0003824 L21SP4_RS10460 0ec5b2deb2275fd519013a232a0c4904 797 Pfam PF07944 Beta-L-arabinofuranosidase, GH127 51 548 1.1E-51 T 22-04-2016 IPR012878 Beta-L-arabinofuranosidase, GH127 KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18 L21SP4_RS10460 0ec5b2deb2275fd519013a232a0c4904 797 PANTHER PTHR31151 92 551 2.8E-37 T 22-04-2016 L21SP4_RS10460 0ec5b2deb2275fd519013a232a0c4904 797 SUPERFAMILY SSF48208 84 363 6.35E-13 T 22-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP4_RS10530 d29314bcf202b6ef129d63bdea981d04 398 PRINTS PR00799 Aspartate aminotransferase signature 205 217 1.5E-35 T 22-04-2016 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 L21SP4_RS10530 d29314bcf202b6ef129d63bdea981d04 398 PRINTS PR00799 Aspartate aminotransferase signature 174 193 1.5E-35 T 22-04-2016 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 L21SP4_RS10530 d29314bcf202b6ef129d63bdea981d04 398 PRINTS PR00799 Aspartate aminotransferase signature 272 297 1.5E-35 T 22-04-2016 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 L21SP4_RS10530 d29314bcf202b6ef129d63bdea981d04 398 PRINTS PR00799 Aspartate aminotransferase signature 340 358 1.5E-35 T 22-04-2016 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 L21SP4_RS10530 d29314bcf202b6ef129d63bdea981d04 398 PANTHER PTHR11879 1 396 3.1E-205 T 22-04-2016 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 L21SP4_RS10530 d29314bcf202b6ef129d63bdea981d04 398 SUPERFAMILY SSF53383 2 396 9.94E-116 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase L21SP4_RS10530 d29314bcf202b6ef129d63bdea981d04 398 Gene3D G3DSA:3.40.640.10 45 314 2.0E-98 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 L21SP4_RS10530 d29314bcf202b6ef129d63bdea981d04 398 Pfam PF00155 Aminotransferase class I and II 27 391 2.5E-83 T 22-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 L21SP4_RS06450 e5a8a458be965c30b91bad385b1b21da 562 PANTHER PTHR31084 2 522 2.0E-158 T 22-04-2016 L21SP4_RS06450 e5a8a458be965c30b91bad385b1b21da 562 SUPERFAMILY SSF48208 29 521 7.29E-63 T 22-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP4_RS06450 e5a8a458be965c30b91bad385b1b21da 562 PANTHER PTHR31084:SF0 2 522 2.0E-158 T 22-04-2016 L21SP4_RS06450 e5a8a458be965c30b91bad385b1b21da 562 Gene3D G3DSA:2.70.98.50 2 159 1.6E-58 T 22-04-2016 IPR027414 Glycosyl hydrolase family, N-terminal domain KEGG: 00511+3.2.1.51 L21SP4_RS02490 50957b96ae2a13216fa6a5126f48a4d5 270 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 117 134 5.1E-14 T 22-04-2016 IPR014032 Peptidase A24A, prepilin type IV, bacterial KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- L21SP4_RS02490 50957b96ae2a13216fa6a5126f48a4d5 270 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 182 192 5.1E-14 T 22-04-2016 IPR014032 Peptidase A24A, prepilin type IV, bacterial KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- L21SP4_RS02490 50957b96ae2a13216fa6a5126f48a4d5 270 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 193 204 5.1E-14 T 22-04-2016 IPR014032 Peptidase A24A, prepilin type IV, bacterial KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- L21SP4_RS02490 50957b96ae2a13216fa6a5126f48a4d5 270 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 205 220 5.1E-14 T 22-04-2016 IPR014032 Peptidase A24A, prepilin type IV, bacterial KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- L21SP4_RS02490 50957b96ae2a13216fa6a5126f48a4d5 270 Pfam PF01478 Type IV leader peptidase family 109 225 1.6E-18 T 22-04-2016 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 L21SP4_RS02490 50957b96ae2a13216fa6a5126f48a4d5 270 PANTHER PTHR30487:SF0 1 267 1.4E-86 T 22-04-2016 L21SP4_RS02490 50957b96ae2a13216fa6a5126f48a4d5 270 Pfam PF06750 Bacterial Peptidase A24 N-terminal domain 15 95 4.2E-33 T 22-04-2016 IPR010627 Peptidase A24A, N-terminal KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- L21SP4_RS02490 50957b96ae2a13216fa6a5126f48a4d5 270 PANTHER PTHR30487 1 267 1.4E-86 T 22-04-2016 L21SP4_RS10380 f1c0b70769cdec1d4e49c7700c1ff3d1 788 SUPERFAMILY SSF46785 707 772 4.93E-22 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS10380 f1c0b70769cdec1d4e49c7700c1ff3d1 788 SMART SM00382 435 625 0.0023 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS10380 f1c0b70769cdec1d4e49c7700c1ff3d1 788 Pfam PF01580 FtsK/SpoIIIE family 402 604 1.2E-53 T 22-04-2016 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 L21SP4_RS10380 f1c0b70769cdec1d4e49c7700c1ff3d1 788 Pfam PF13491 4TM region of DNA translocase FtsK/SpoIIIE 14 175 3.9E-17 T 22-04-2016 IPR025199 DNA translocase FtsK, 4TM region L21SP4_RS10380 f1c0b70769cdec1d4e49c7700c1ff3d1 788 PANTHER PTHR22683:SF41 205 770 3.6E-197 T 22-04-2016 L21SP4_RS10380 f1c0b70769cdec1d4e49c7700c1ff3d1 788 SUPERFAMILY SSF52540 374 677 1.23E-43 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS10380 f1c0b70769cdec1d4e49c7700c1ff3d1 788 Gene3D G3DSA:3.40.50.300 374 670 4.1E-77 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS10380 f1c0b70769cdec1d4e49c7700c1ff3d1 788 Pfam PF09397 Ftsk gamma domain 709 769 5.6E-28 T 22-04-2016 IPR018541 FtsK gamma domain L21SP4_RS10380 f1c0b70769cdec1d4e49c7700c1ff3d1 788 PANTHER PTHR22683 205 770 3.6E-197 T 22-04-2016 L21SP4_RS10380 f1c0b70769cdec1d4e49c7700c1ff3d1 788 SMART SM00843 707 772 4.8E-34 T 22-04-2016 IPR018541 FtsK gamma domain L21SP4_RS05750 58304fd04554cf06be1c05429dd52680 339 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 4 336 7.3E-138 T 22-04-2016 IPR006321 Pilus retraction protein PilT GO:0005524|GO:0006810 L21SP4_RS05750 58304fd04554cf06be1c05429dd52680 339 PANTHER PTHR30486 2 337 5.3E-146 T 22-04-2016 L21SP4_RS05750 58304fd04554cf06be1c05429dd52680 339 SMART SM00382 124 258 4.4E-7 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS05750 58304fd04554cf06be1c05429dd52680 339 Gene3D G3DSA:3.40.50.300 104 336 1.8E-64 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS05750 58304fd04554cf06be1c05429dd52680 339 SUPERFAMILY SSF52540 4 336 2.66E-67 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS05750 58304fd04554cf06be1c05429dd52680 339 Gene3D G3DSA:3.30.450.90 5 101 1.9E-4 T 22-04-2016 L21SP4_RS05750 58304fd04554cf06be1c05429dd52680 339 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 195 209 - T 22-04-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 L21SP4_RS05750 58304fd04554cf06be1c05429dd52680 339 PANTHER PTHR30486:SF6 2 337 5.3E-146 T 22-04-2016 L21SP4_RS05750 58304fd04554cf06be1c05429dd52680 339 Pfam PF00437 Type II/IV secretion system protein 107 244 8.3E-39 T 22-04-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 L21SP4_RS06615 def72cb6b001bf594eb880ebd57514b9 517 PANTHER PTHR33678:SF2 17 517 2.7E-126 T 22-04-2016 L21SP4_RS06615 def72cb6b001bf594eb880ebd57514b9 517 PANTHER PTHR33678 17 517 2.7E-126 T 22-04-2016 L21SP4_RS06615 def72cb6b001bf594eb880ebd57514b9 517 Pfam PF13005 zinc-finger binding domain of transposase IS66 130 173 2.2E-7 T 22-04-2016 IPR024474 Zinc-finger binding domain of transposase IS66 L21SP4_RS06615 def72cb6b001bf594eb880ebd57514b9 517 Pfam PF03050 Transposase IS66 family 189 479 4.9E-60 T 22-04-2016 IPR004291 Transposase, IS66 L21SP4_RS10295 886e9a8d2fe66348006239261df4c9a9 682 SUPERFAMILY SSF52172 24 134 1.01E-8 T 22-04-2016 IPR011006 CheY-like superfamily L21SP4_RS10295 886e9a8d2fe66348006239261df4c9a9 682 Gene3D G3DSA:3.30.450.40 152 318 1.2E-11 T 22-04-2016 IPR029016 GAF domain-like L21SP4_RS10295 886e9a8d2fe66348006239261df4c9a9 682 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 548 659 2.4E-18 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS10295 886e9a8d2fe66348006239261df4c9a9 682 Gene3D G3DSA:3.30.450.20 321 435 2.1E-10 T 22-04-2016 L21SP4_RS10295 886e9a8d2fe66348006239261df4c9a9 682 SUPERFAMILY SSF55785 312 423 6.49E-8 T 22-04-2016 IPR000014 PAS domain L21SP4_RS10295 886e9a8d2fe66348006239261df4c9a9 682 SUPERFAMILY SSF47384 429 505 3.14E-14 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS10295 886e9a8d2fe66348006239261df4c9a9 682 Gene3D G3DSA:3.30.565.10 507 659 1.2E-35 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS10295 886e9a8d2fe66348006239261df4c9a9 682 Gene3D G3DSA:3.40.50.2300 28 136 1.9E-8 T 22-04-2016 L21SP4_RS10295 886e9a8d2fe66348006239261df4c9a9 682 Pfam PF00512 His Kinase A (phospho-acceptor) domain 442 502 2.1E-11 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS10295 886e9a8d2fe66348006239261df4c9a9 682 SMART SM00387 548 660 5.5E-29 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS10295 886e9a8d2fe66348006239261df4c9a9 682 Gene3D G3DSA:1.10.287.130 436 501 5.6E-13 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS10295 886e9a8d2fe66348006239261df4c9a9 682 SUPERFAMILY SSF55781 152 326 2.04E-13 T 22-04-2016 IPR029016 GAF domain-like L21SP4_RS10295 886e9a8d2fe66348006239261df4c9a9 682 PANTHER PTHR24423 26 83 6.9E-73 T 22-04-2016 L21SP4_RS10295 886e9a8d2fe66348006239261df4c9a9 682 PANTHER PTHR24423 317 674 6.9E-73 T 22-04-2016 L21SP4_RS10295 886e9a8d2fe66348006239261df4c9a9 682 PANTHER PTHR24423 114 133 6.9E-73 T 22-04-2016 L21SP4_RS10295 886e9a8d2fe66348006239261df4c9a9 682 SMART SM00388 440 506 2.0E-12 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS10295 886e9a8d2fe66348006239261df4c9a9 682 Pfam PF08448 PAS fold 325 427 1.7E-13 T 22-04-2016 IPR013656 PAS fold-4 L21SP4_RS10295 886e9a8d2fe66348006239261df4c9a9 682 SUPERFAMILY SSF55874 491 658 1.44E-31 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS10295 886e9a8d2fe66348006239261df4c9a9 682 PRINTS PR00344 Bacterial sensor protein C-terminal signature 610 620 2.4E-14 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS10295 886e9a8d2fe66348006239261df4c9a9 682 PRINTS PR00344 Bacterial sensor protein C-terminal signature 592 606 2.4E-14 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS10295 886e9a8d2fe66348006239261df4c9a9 682 PRINTS PR00344 Bacterial sensor protein C-terminal signature 621 639 2.4E-14 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS10295 886e9a8d2fe66348006239261df4c9a9 682 PRINTS PR00344 Bacterial sensor protein C-terminal signature 644 657 2.4E-14 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS11995 4366d608ed3397e54e15a4e692ec31de 289 SUPERFAMILY SSF46689 182 231 7.79E-7 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS11995 4366d608ed3397e54e15a4e692ec31de 289 SUPERFAMILY SSF46689 235 285 5.82E-11 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS11995 4366d608ed3397e54e15a4e692ec31de 289 SMART SM00342 197 281 7.3E-22 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP4_RS11995 4366d608ed3397e54e15a4e692ec31de 289 Gene3D G3DSA:1.10.10.60 235 283 1.7E-12 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS11995 4366d608ed3397e54e15a4e692ec31de 289 SUPERFAMILY SSF51215 42 148 7.19E-8 T 22-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 L21SP4_RS11995 4366d608ed3397e54e15a4e692ec31de 289 Gene3D G3DSA:1.10.10.60 183 234 6.4E-11 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS11995 4366d608ed3397e54e15a4e692ec31de 289 PANTHER PTHR11019 10 289 2.4E-31 T 22-04-2016 L21SP4_RS11995 4366d608ed3397e54e15a4e692ec31de 289 Pfam PF02311 AraC-like ligand binding domain 53 151 3.5E-6 T 22-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 L21SP4_RS11995 4366d608ed3397e54e15a4e692ec31de 289 Pfam PF12833 Helix-turn-helix domain 204 283 8.8E-19 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP4_RS11995 4366d608ed3397e54e15a4e692ec31de 289 Gene3D G3DSA:2.60.120.280 42 150 1.0E-4 T 22-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 L21SP4_RS05365 171f8c294569a346fe45ff42ebabfd07 289 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 213 250 3.1E-13 T 22-04-2016 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain UniPathway: UPA00070 L21SP4_RS05365 171f8c294569a346fe45ff42ebabfd07 289 PANTHER PTHR11938:SF47 55 258 1.3E-54 T 22-04-2016 L21SP4_RS05365 171f8c294569a346fe45ff42ebabfd07 289 PIRSF PIRSF006816 1 256 3.5E-69 T 22-04-2016 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 UniPathway: UPA00070 L21SP4_RS05365 171f8c294569a346fe45ff42ebabfd07 289 Gene3D G3DSA:3.40.50.80 95 211 1.8E-36 T 22-04-2016 L21SP4_RS05365 171f8c294569a346fe45ff42ebabfd07 289 Gene3D G3DSA:2.10.240.10 219 250 3.3E-5 T 22-04-2016 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain UniPathway: UPA00070 L21SP4_RS05365 171f8c294569a346fe45ff42ebabfd07 289 Pfam PF00175 Oxidoreductase NAD-binding domain 105 197 1.3E-4 T 22-04-2016 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 L21SP4_RS05365 171f8c294569a346fe45ff42ebabfd07 289 SUPERFAMILY SSF63380 3 93 2.77E-19 T 22-04-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 L21SP4_RS05365 171f8c294569a346fe45ff42ebabfd07 289 SUPERFAMILY SSF52343 89 249 4.98E-33 T 22-04-2016 L21SP4_RS05365 171f8c294569a346fe45ff42ebabfd07 289 PANTHER PTHR11938 55 258 1.3E-54 T 22-04-2016 L21SP4_RS05365 171f8c294569a346fe45ff42ebabfd07 289 Gene3D G3DSA:2.40.30.10 2 92 8.6E-25 T 22-04-2016 L21SP4_RS06640 1f1f1082cee22860a119eca4cd54c909 334 SUPERFAMILY SSF51735 126 274 2.01E-26 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS06640 1f1f1082cee22860a119eca4cd54c909 334 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 34 101 9.7E-9 T 22-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 L21SP4_RS06640 1f1f1082cee22860a119eca4cd54c909 334 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 74 88 - T 22-04-2016 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 L21SP4_RS06640 1f1f1082cee22860a119eca4cd54c909 334 PANTHER PTHR11695 18 332 3.8E-53 T 22-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 L21SP4_RS06640 1f1f1082cee22860a119eca4cd54c909 334 Gene3D G3DSA:3.40.50.720 155 270 7.1E-27 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS06640 1f1f1082cee22860a119eca4cd54c909 334 Gene3D G3DSA:3.90.180.10 1 100 2.4E-19 T 22-04-2016 IPR011032 GroES-like L21SP4_RS06640 1f1f1082cee22860a119eca4cd54c909 334 Gene3D G3DSA:3.90.180.10 101 154 8.4E-7 T 22-04-2016 IPR011032 GroES-like L21SP4_RS06640 1f1f1082cee22860a119eca4cd54c909 334 SUPERFAMILY SSF50129 3 160 7.7E-28 T 22-04-2016 IPR011032 GroES-like L21SP4_RS06640 1f1f1082cee22860a119eca4cd54c909 334 PANTHER PTHR11695:SF38 18 332 3.8E-53 T 22-04-2016 L21SP4_RS06640 1f1f1082cee22860a119eca4cd54c909 334 Pfam PF00107 Zinc-binding dehydrogenase 169 280 2.3E-18 T 22-04-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 L21SP4_RS07575 c0f1cf7ac8c55a6479e3e90cf281060b 77 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 8 48 8.6E-8 T 22-04-2016 IPR007159 SpoVT-AbrB domain GO:0003677 L21SP4_RS07575 c0f1cf7ac8c55a6479e3e90cf281060b 77 SUPERFAMILY SSF89447 1 61 5.76E-11 T 22-04-2016 L21SP4_RS07575 c0f1cf7ac8c55a6479e3e90cf281060b 77 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 6 46 7.8E-11 T 22-04-2016 IPR007159 SpoVT-AbrB domain GO:0003677 L21SP4_RS07575 c0f1cf7ac8c55a6479e3e90cf281060b 77 Gene3D G3DSA:2.10.260.10 5 46 3.9E-11 T 22-04-2016 L21SP4_RS07575 c0f1cf7ac8c55a6479e3e90cf281060b 77 SMART SM00966 6 51 1.5E-9 T 22-04-2016 IPR007159 SpoVT-AbrB domain GO:0003677 L21SP4_RS11420 5d9ced3c35c151a701ec413c9f5aa02b 441 SUPERFAMILY SSF102114 134 367 3.4E-59 T 22-04-2016 L21SP4_RS11420 5d9ced3c35c151a701ec413c9f5aa02b 441 PANTHER PTHR11918:SF45 23 431 1.4E-86 T 22-04-2016 L21SP4_RS11420 5d9ced3c35c151a701ec413c9f5aa02b 441 SMART SM00729 147 363 2.3E-50 T 22-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 L21SP4_RS11420 5d9ced3c35c151a701ec413c9f5aa02b 441 Pfam PF04055 Radical SAM superfamily 153 320 1.5E-22 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 L21SP4_RS11420 5d9ced3c35c151a701ec413c9f5aa02b 441 PANTHER PTHR11918 23 431 1.4E-86 T 22-04-2016 IPR023970 Methylthiotransferase/radical SAM-type protein L21SP4_RS11420 5d9ced3c35c151a701ec413c9f5aa02b 441 Pfam PF00919 Uncharacterized protein family UPF0004 24 99 9.0E-13 T 22-04-2016 IPR013848 Methylthiotransferase, N-terminal GO:0003824|GO:0009451|GO:0051539 L21SP4_RS11420 5d9ced3c35c151a701ec413c9f5aa02b 441 Gene3D G3DSA:3.80.30.20 146 372 2.0E-67 T 22-04-2016 IPR023404 Radical SAM, alpha/beta horseshoe L21SP4_RS11420 5d9ced3c35c151a701ec413c9f5aa02b 441 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 151 171 - T 22-04-2016 IPR020612 Methylthiotransferase, conserved site GO:0051539 L21SP4_RS11420 5d9ced3c35c151a701ec413c9f5aa02b 441 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 22 433 1.8E-97 T 22-04-2016 IPR005839 Methylthiotransferase GO:0016740|GO:0043412|GO:0051539 L21SP4_RS08695 dc727ad1d55bf56ab61c822a25a99720 363 TIGRFAM TIGR00169 leuB: 3-isopropylmalate dehydrogenase 6 352 1.2E-142 T 22-04-2016 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396|UniPathway: UPA00048 L21SP4_RS08695 dc727ad1d55bf56ab61c822a25a99720 363 PANTHER PTHR11835:SF35 1 362 3.9E-182 T 22-04-2016 L21SP4_RS08695 dc727ad1d55bf56ab61c822a25a99720 363 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 7 352 1.5E-126 T 22-04-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 L21SP4_RS08695 dc727ad1d55bf56ab61c822a25a99720 363 Hamap MF_01033 3-isopropylmalate dehydrogenase [leuB]. 5 357 47.623 T 22-04-2016 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396|UniPathway: UPA00048 L21SP4_RS08695 dc727ad1d55bf56ab61c822a25a99720 363 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 246 265 - T 22-04-2016 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: REACT_1046 L21SP4_RS08695 dc727ad1d55bf56ab61c822a25a99720 363 Gene3D G3DSA:3.40.718.10 2 356 2.1E-125 T 22-04-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 L21SP4_RS08695 dc727ad1d55bf56ab61c822a25a99720 363 PANTHER PTHR11835 1 362 3.9E-182 T 22-04-2016 IPR001804 Isocitrate and isopropylmalate dehydrogenases family GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: REACT_1046 L21SP4_RS08695 dc727ad1d55bf56ab61c822a25a99720 363 SMART SM01329 6 353 2.3E-183 T 22-04-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 L21SP4_RS08695 dc727ad1d55bf56ab61c822a25a99720 363 SUPERFAMILY SSF53659 3 355 1.47E-117 T 22-04-2016 L21SP4_RS02440 3eb67fb88827052daf48734260d2fa87 288 PANTHER PTHR31964 3 158 3.6E-15 T 22-04-2016 L21SP4_RS02440 3eb67fb88827052daf48734260d2fa87 288 Pfam PF00582 Universal stress protein family 8 157 1.9E-15 T 22-04-2016 IPR006016 UspA GO:0006950 L21SP4_RS02440 3eb67fb88827052daf48734260d2fa87 288 Pfam PF00582 Universal stress protein family 164 288 1.9E-17 T 22-04-2016 IPR006016 UspA GO:0006950 L21SP4_RS02440 3eb67fb88827052daf48734260d2fa87 288 Gene3D G3DSA:3.40.50.620 163 288 2.2E-24 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP4_RS02440 3eb67fb88827052daf48734260d2fa87 288 Gene3D G3DSA:3.40.50.620 4 158 4.2E-24 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP4_RS02440 3eb67fb88827052daf48734260d2fa87 288 SUPERFAMILY SSF52402 9 158 1.26E-21 T 22-04-2016 L21SP4_RS02440 3eb67fb88827052daf48734260d2fa87 288 PRINTS PR01438 Universal stress protein signature 266 288 2.3E-7 T 22-04-2016 IPR006015 Universal stress protein A L21SP4_RS02440 3eb67fb88827052daf48734260d2fa87 288 PRINTS PR01438 Universal stress protein signature 163 181 2.3E-7 T 22-04-2016 IPR006015 Universal stress protein A L21SP4_RS02440 3eb67fb88827052daf48734260d2fa87 288 SUPERFAMILY SSF52402 164 288 8.37E-24 T 22-04-2016 L21SP4_RS05230 5f4a72152be5026faf0adfc8b0ee352d 154 SUPERFAMILY SSF52540 23 133 1.49E-22 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS05230 5f4a72152be5026faf0adfc8b0ee352d 154 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 19 135 1.9E-38 T 22-04-2016 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 L21SP4_RS05230 5f4a72152be5026faf0adfc8b0ee352d 154 PANTHER PTHR33540 18 143 4.7E-47 T 22-04-2016 L21SP4_RS05230 5f4a72152be5026faf0adfc8b0ee352d 154 PANTHER PTHR33540:SF2 18 143 4.7E-47 T 22-04-2016 L21SP4_RS05230 5f4a72152be5026faf0adfc8b0ee352d 154 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 21 137 9.6E-37 T 22-04-2016 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 L21SP4_RS05230 5f4a72152be5026faf0adfc8b0ee352d 154 Gene3D G3DSA:3.40.50.300 18 144 3.7E-44 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS05830 867aac38145128b688831ef41854d428 253 SUPERFAMILY SSF75625 5 246 7.85E-88 T 22-04-2016 IPR029072 YebC-like L21SP4_RS05830 867aac38145128b688831ef41854d428 253 Gene3D G3DSA:1.10.10.200 1 78 2.0E-35 T 22-04-2016 IPR017856 Integrase, N-terminal zinc-binding domain-like L21SP4_RS05830 867aac38145128b688831ef41854d428 253 PANTHER PTHR12532:SF0 1 242 4.0E-101 T 22-04-2016 L21SP4_RS05830 867aac38145128b688831ef41854d428 253 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 240 33.844 T 22-04-2016 IPR002876 Transcriptional regulator TACO1-like L21SP4_RS05830 867aac38145128b688831ef41854d428 253 Gene3D G3DSA:3.30.1270.10 83 136 1.6E-33 T 22-04-2016 IPR026563 Transcriptional regulator TACO1-like, domain 2 L21SP4_RS05830 867aac38145128b688831ef41854d428 253 Gene3D G3DSA:3.30.1270.10 213 248 1.6E-33 T 22-04-2016 IPR026563 Transcriptional regulator TACO1-like, domain 2 L21SP4_RS05830 867aac38145128b688831ef41854d428 253 Pfam PF01709 Transcriptional regulator 5 235 2.8E-87 T 22-04-2016 IPR002876 Transcriptional regulator TACO1-like L21SP4_RS05830 867aac38145128b688831ef41854d428 253 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 237 1.8E-92 T 22-04-2016 IPR002876 Transcriptional regulator TACO1-like L21SP4_RS05830 867aac38145128b688831ef41854d428 253 PANTHER PTHR12532 1 242 4.0E-101 T 22-04-2016 IPR002876 Transcriptional regulator TACO1-like L21SP4_RS05830 867aac38145128b688831ef41854d428 253 Gene3D G3DSA:3.30.70.980 137 204 8.4E-25 T 22-04-2016 IPR026564 Transcriptional regulator TACO1-like, domain 3 L21SP4_RS02740 3069d21fb9b4550e0cf5252059f3b337 399 PRINTS PR00477 Phosphoglycerate kinase family signature 374 391 4.87E-93 T 22-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 L21SP4_RS02740 3069d21fb9b4550e0cf5252059f3b337 399 PRINTS PR00477 Phosphoglycerate kinase family signature 351 362 4.87E-93 T 22-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 L21SP4_RS02740 3069d21fb9b4550e0cf5252059f3b337 399 PRINTS PR00477 Phosphoglycerate kinase family signature 31 53 4.87E-93 T 22-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 L21SP4_RS02740 3069d21fb9b4550e0cf5252059f3b337 399 PRINTS PR00477 Phosphoglycerate kinase family signature 197 216 4.87E-93 T 22-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 L21SP4_RS02740 3069d21fb9b4550e0cf5252059f3b337 399 PRINTS PR00477 Phosphoglycerate kinase family signature 318 343 4.87E-93 T 22-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 L21SP4_RS02740 3069d21fb9b4550e0cf5252059f3b337 399 PRINTS PR00477 Phosphoglycerate kinase family signature 10 26 4.87E-93 T 22-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 L21SP4_RS02740 3069d21fb9b4550e0cf5252059f3b337 399 PRINTS PR00477 Phosphoglycerate kinase family signature 174 196 4.87E-93 T 22-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 L21SP4_RS02740 3069d21fb9b4550e0cf5252059f3b337 399 PRINTS PR00477 Phosphoglycerate kinase family signature 109 124 4.87E-93 T 22-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 L21SP4_RS02740 3069d21fb9b4550e0cf5252059f3b337 399 PRINTS PR00477 Phosphoglycerate kinase family signature 143 165 4.87E-93 T 22-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 L21SP4_RS02740 3069d21fb9b4550e0cf5252059f3b337 399 Gene3D G3DSA:3.40.50.1270 186 386 1.6E-83 T 22-04-2016 IPR015901 Phosphoglycerate kinase, C-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 L21SP4_RS02740 3069d21fb9b4550e0cf5252059f3b337 399 PIRSF PIRSF000724 1 399 2.0E-150 T 22-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 L21SP4_RS02740 3069d21fb9b4550e0cf5252059f3b337 399 Gene3D G3DSA:3.40.50.1260 4 185 1.7E-74 T 22-04-2016 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 L21SP4_RS02740 3069d21fb9b4550e0cf5252059f3b337 399 PANTHER PTHR11406 1 399 5.7E-235 T 22-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 L21SP4_RS02740 3069d21fb9b4550e0cf5252059f3b337 399 Pfam PF00162 Phosphoglycerate kinase 6 388 5.4E-160 T 22-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 L21SP4_RS02740 3069d21fb9b4550e0cf5252059f3b337 399 SUPERFAMILY SSF53748 1 398 1.18E-157 T 22-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 L21SP4_RS02740 3069d21fb9b4550e0cf5252059f3b337 399 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 15 25 - T 22-04-2016 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 L21SP4_RS02740 3069d21fb9b4550e0cf5252059f3b337 399 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 8 398 41.658 T 22-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 L21SP4_RS08855 8799d98a409e298217c814ea9d762699 644 Gene3D G3DSA:2.170.220.10 118 227 1.5E-40 T 22-04-2016 L21SP4_RS08855 8799d98a409e298217c814ea9d762699 644 Pfam PF01588 Putative tRNA binding domain 550 641 1.2E-24 T 22-04-2016 IPR002547 tRNA-binding domain GO:0000049 Reactome: REACT_71 L21SP4_RS08855 8799d98a409e298217c814ea9d762699 644 PANTHER PTHR11946 7 600 8.4E-251 T 22-04-2016 L21SP4_RS08855 8799d98a409e298217c814ea9d762699 644 Gene3D G3DSA:1.10.730.10 339 511 5.9E-42 T 22-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 L21SP4_RS08855 8799d98a409e298217c814ea9d762699 644 Gene3D G3DSA:3.40.50.620 228 338 1.4E-74 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP4_RS08855 8799d98a409e298217c814ea9d762699 644 Gene3D G3DSA:3.40.50.620 6 115 1.4E-74 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP4_RS08855 8799d98a409e298217c814ea9d762699 644 PANTHER PTHR11946:SF1 7 600 8.4E-251 T 22-04-2016 L21SP4_RS08855 8799d98a409e298217c814ea9d762699 644 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 530 643 5.2E-42 T 22-04-2016 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 L21SP4_RS08855 8799d98a409e298217c814ea9d762699 644 Hamap MF_01228 Methionine--tRNA ligase [metG]. 1 511 45.881 T 22-04-2016 IPR023457 Methionine-tRNA synthetase, type 2 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 L21SP4_RS08855 8799d98a409e298217c814ea9d762699 644 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 7 497 1.5E-150 T 22-04-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 L21SP4_RS08855 8799d98a409e298217c814ea9d762699 644 SUPERFAMILY SSF47323 351 511 3.18E-30 T 22-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 L21SP4_RS08855 8799d98a409e298217c814ea9d762699 644 Pfam PF09334 tRNA synthetases class I (M) 7 151 2.2E-49 T 22-04-2016 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 L21SP4_RS08855 8799d98a409e298217c814ea9d762699 644 Pfam PF09334 tRNA synthetases class I (M) 158 363 4.1E-61 T 22-04-2016 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 L21SP4_RS08855 8799d98a409e298217c814ea9d762699 644 Gene3D G3DSA:2.40.50.140 537 643 2.8E-37 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold L21SP4_RS08855 8799d98a409e298217c814ea9d762699 644 SUPERFAMILY SSF52374 6 349 1.82E-109 T 22-04-2016 L21SP4_RS08855 8799d98a409e298217c814ea9d762699 644 SUPERFAMILY SSF50249 543 643 2.94E-31 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold L21SP4_RS08855 8799d98a409e298217c814ea9d762699 644 PRINTS PR01041 Methionyl-tRNA synthetase signature 258 273 3.0E-31 T 22-04-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 L21SP4_RS08855 8799d98a409e298217c814ea9d762699 644 PRINTS PR01041 Methionyl-tRNA synthetase signature 226 237 3.0E-31 T 22-04-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 L21SP4_RS08855 8799d98a409e298217c814ea9d762699 644 PRINTS PR01041 Methionyl-tRNA synthetase signature 41 55 3.0E-31 T 22-04-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 L21SP4_RS08855 8799d98a409e298217c814ea9d762699 644 PRINTS PR01041 Methionyl-tRNA synthetase signature 89 100 3.0E-31 T 22-04-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 L21SP4_RS08855 8799d98a409e298217c814ea9d762699 644 PRINTS PR01041 Methionyl-tRNA synthetase signature 350 361 3.0E-31 T 22-04-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 L21SP4_RS08855 8799d98a409e298217c814ea9d762699 644 PRINTS PR01041 Methionyl-tRNA synthetase signature 9 22 3.0E-31 T 22-04-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 L21SP4_RS10165 f84ea5f738e96ac004a8c2066d704ade 279 PANTHER PTHR10108 3 266 3.1E-19 T 22-04-2016 L21SP4_RS10165 f84ea5f738e96ac004a8c2066d704ade 279 PANTHER PTHR10108:SF90 3 266 3.1E-19 T 22-04-2016 L21SP4_RS10165 f84ea5f738e96ac004a8c2066d704ade 279 SUPERFAMILY SSF53335 7 278 4.39E-53 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS10165 f84ea5f738e96ac004a8c2066d704ade 279 Pfam PF08241 Methyltransferase domain 71 169 1.5E-15 T 22-04-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 L21SP4_RS10165 f84ea5f738e96ac004a8c2066d704ade 279 Gene3D G3DSA:3.40.50.150 54 176 5.3E-16 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS10165 f84ea5f738e96ac004a8c2066d704ade 279 Gene3D G3DSA:1.10.287.840 7 42 6.1E-44 T 22-04-2016 IPR023143 Mycolic acid cyclopropane synthase-like domain UniPathway: UPA00530 L21SP4_RS10165 f84ea5f738e96ac004a8c2066d704ade 279 Gene3D G3DSA:1.10.287.840 177 270 6.1E-44 T 22-04-2016 IPR023143 Mycolic acid cyclopropane synthase-like domain UniPathway: UPA00530 L21SP4_RS10035 d01ee6319a335d6cca88de5bfdf83889 218 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 6 52 3.6E-15 T 22-04-2016 IPR010093 SinI-like, DNA-binding domain GO:0003677 L21SP4_RS10035 d01ee6319a335d6cca88de5bfdf83889 218 PANTHER PTHR30505:SF5 74 215 2.6E-27 T 22-04-2016 L21SP4_RS10035 d01ee6319a335d6cca88de5bfdf83889 218 PANTHER PTHR30505 74 215 2.6E-27 T 22-04-2016 L21SP4_RS10035 d01ee6319a335d6cca88de5bfdf83889 218 Gene3D G3DSA:3.40.930.10 74 216 8.3E-30 T 22-04-2016 IPR002178 PTS EIIA type-2 domain KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- L21SP4_RS10035 d01ee6319a335d6cca88de5bfdf83889 218 SUPERFAMILY SSF46955 5 54 2.56E-10 T 22-04-2016 IPR009061 Putative DNA-binding domain L21SP4_RS10035 d01ee6319a335d6cca88de5bfdf83889 218 SUPERFAMILY SSF55804 78 216 4.32E-24 T 22-04-2016 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: REACT_15518 L21SP4_RS10035 d01ee6319a335d6cca88de5bfdf83889 218 Pfam PF12728 Helix-turn-helix domain 6 54 2.5E-18 T 22-04-2016 L21SP4_RS10035 d01ee6319a335d6cca88de5bfdf83889 218 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 76 215 3.1E-26 T 22-04-2016 IPR002178 PTS EIIA type-2 domain KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- L21SP4_RS10035 d01ee6319a335d6cca88de5bfdf83889 218 Gene3D G3DSA:1.10.10.10 6 59 5.5E-11 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS10085 492465a9f2ac8004e50bf0dce964306b 308 Gene3D G3DSA:3.20.20.70 7 304 5.7E-84 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP4_RS10085 492465a9f2ac8004e50bf0dce964306b 308 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 11 304 1.1E-99 T 22-04-2016 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 L21SP4_RS10085 492465a9f2ac8004e50bf0dce964306b 308 Pfam PF01180 Dihydroorotate dehydrogenase 11 292 6.6E-61 T 22-04-2016 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 L21SP4_RS10085 492465a9f2ac8004e50bf0dce964306b 308 PANTHER PTHR11938:SF5 10 304 4.0E-51 T 22-04-2016 L21SP4_RS10085 492465a9f2ac8004e50bf0dce964306b 308 PANTHER PTHR11938 10 304 4.0E-51 T 22-04-2016 L21SP4_RS10085 492465a9f2ac8004e50bf0dce964306b 308 Hamap MF_00224 Dihydroorotate dehydrogenase [pyrD]. 11 306 37.55 T 22-04-2016 IPR024920 Dihydroorotate dehydrogenase, class 1 GO:0004152|GO:0005737|GO:0006221 L21SP4_RS10085 492465a9f2ac8004e50bf0dce964306b 308 SUPERFAMILY SSF51395 8 304 2.02E-78 T 22-04-2016 L21SP4_RS10085 492465a9f2ac8004e50bf0dce964306b 308 PIRSF PIRSF000164 1 305 3.4E-73 T 22-04-2016 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 Reactome: REACT_1698 L21SP4_RS01965 2d246ec4527dd6e193fb3dea948ddf40 768 SUPERFAMILY SSF51126 48 368 2.69E-17 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor L21SP4_RS01965 2d246ec4527dd6e193fb3dea948ddf40 768 SUPERFAMILY SSF51126 268 298 3.43E-18 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor L21SP4_RS01965 2d246ec4527dd6e193fb3dea948ddf40 768 SUPERFAMILY SSF51126 16 116 3.43E-18 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor L21SP4_RS01965 2d246ec4527dd6e193fb3dea948ddf40 768 SUPERFAMILY SSF51126 452 634 3.43E-18 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor L21SP4_RS01965 2d246ec4527dd6e193fb3dea948ddf40 768 Gene3D G3DSA:2.160.20.10 16 318 1.3E-20 T 22-04-2016 IPR012334 Pectin lyase fold L21SP4_RS01965 2d246ec4527dd6e193fb3dea948ddf40 768 Gene3D G3DSA:2.160.20.10 409 634 3.0E-15 T 22-04-2016 IPR012334 Pectin lyase fold L21SP4_RS10510 29825b68577436beb1ed15e6551ae28d 431 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 239 276 - T 22-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 L21SP4_RS10510 29825b68577436beb1ed15e6551ae28d 431 Gene3D G3DSA:3.90.1150.10 3 63 3.5E-48 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 L21SP4_RS10510 29825b68577436beb1ed15e6551ae28d 431 Gene3D G3DSA:3.90.1150.10 331 426 3.5E-48 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 L21SP4_RS10510 29825b68577436beb1ed15e6551ae28d 431 SUPERFAMILY SSF53383 5 425 5.98E-122 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase L21SP4_RS10510 29825b68577436beb1ed15e6551ae28d 431 PANTHER PTHR11986 1 431 9.0E-147 T 22-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 L21SP4_RS10510 29825b68577436beb1ed15e6551ae28d 431 Gene3D G3DSA:3.40.640.10 64 328 3.1E-84 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 L21SP4_RS10510 29825b68577436beb1ed15e6551ae28d 431 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 14 424 9.8E-140 T 22-04-2016 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62|UniPathway: UPA00078 L21SP4_RS10510 29825b68577436beb1ed15e6551ae28d 431 PANTHER PTHR11986:SF8 1 431 9.0E-147 T 22-04-2016 L21SP4_RS10510 29825b68577436beb1ed15e6551ae28d 431 Pfam PF00202 Aminotransferase class-III 29 424 3.8E-103 T 22-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 L21SP4_RS03745 3c718e9d530732841b852f4b3f6a2dcf 1029 SUPERFAMILY SSF82714 181 264 1.28E-13 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains L21SP4_RS03745 3c718e9d530732841b852f4b3f6a2dcf 1029 PRINTS PR00702 Acriflavin resistance protein family signature 458 481 5.6E-30 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 L21SP4_RS03745 3c718e9d530732841b852f4b3f6a2dcf 1029 PRINTS PR00702 Acriflavin resistance protein family signature 352 373 5.6E-30 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 L21SP4_RS03745 3c718e9d530732841b852f4b3f6a2dcf 1029 PRINTS PR00702 Acriflavin resistance protein family signature 380 404 5.6E-30 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 L21SP4_RS03745 3c718e9d530732841b852f4b3f6a2dcf 1029 PRINTS PR00702 Acriflavin resistance protein family signature 608 622 5.6E-30 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 L21SP4_RS03745 3c718e9d530732841b852f4b3f6a2dcf 1029 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 5.6E-30 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 L21SP4_RS03745 3c718e9d530732841b852f4b3f6a2dcf 1029 PRINTS PR00702 Acriflavin resistance protein family signature 433 456 5.6E-30 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 L21SP4_RS03745 3c718e9d530732841b852f4b3f6a2dcf 1029 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 5.6E-30 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 L21SP4_RS03745 3c718e9d530732841b852f4b3f6a2dcf 1029 SUPERFAMILY SSF82866 785 1021 1.44E-42 T 22-04-2016 L21SP4_RS03745 3c718e9d530732841b852f4b3f6a2dcf 1029 PANTHER PTHR32063 1 1029 7.0E-290 T 22-04-2016 L21SP4_RS03745 3c718e9d530732841b852f4b3f6a2dcf 1029 Gene3D G3DSA:3.30.2090.10 701 789 2.3E-10 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains L21SP4_RS03745 3c718e9d530732841b852f4b3f6a2dcf 1029 SUPERFAMILY SSF82693 554 647 2.07E-8 T 22-04-2016 L21SP4_RS03745 3c718e9d530732841b852f4b3f6a2dcf 1029 Gene3D G3DSA:3.30.70.1430 40 136 4.7E-24 T 22-04-2016 L21SP4_RS03745 3c718e9d530732841b852f4b3f6a2dcf 1029 SUPERFAMILY SSF82693 136 180 5.76E-14 T 22-04-2016 L21SP4_RS03745 3c718e9d530732841b852f4b3f6a2dcf 1029 SUPERFAMILY SSF82693 266 320 5.76E-14 T 22-04-2016 L21SP4_RS03745 3c718e9d530732841b852f4b3f6a2dcf 1029 SUPERFAMILY SSF82693 40 133 7.15E-23 T 22-04-2016 L21SP4_RS03745 3c718e9d530732841b852f4b3f6a2dcf 1029 Pfam PF00873 AcrB/AcrD/AcrF family 4 1020 9.0E-204 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 L21SP4_RS03745 3c718e9d530732841b852f4b3f6a2dcf 1029 Gene3D G3DSA:3.30.70.1430 554 642 9.7E-7 T 22-04-2016 L21SP4_RS03745 3c718e9d530732841b852f4b3f6a2dcf 1029 PANTHER PTHR32063:SF0 1 1029 7.0E-290 T 22-04-2016 L21SP4_RS03745 3c718e9d530732841b852f4b3f6a2dcf 1029 SUPERFAMILY SSF82714 701 788 1.7E-10 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains L21SP4_RS03745 3c718e9d530732841b852f4b3f6a2dcf 1029 Gene3D G3DSA:1.20.1640.10 283 493 2.9E-53 T 22-04-2016 L21SP4_RS03745 3c718e9d530732841b852f4b3f6a2dcf 1029 Gene3D G3DSA:1.10.3850.10 793 1020 1.8E-57 T 22-04-2016 L21SP4_RS03745 3c718e9d530732841b852f4b3f6a2dcf 1029 Gene3D G3DSA:3.30.2090.10 181 264 2.8E-14 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains L21SP4_RS03745 3c718e9d530732841b852f4b3f6a2dcf 1029 SUPERFAMILY SSF82866 288 485 4.97E-45 T 22-04-2016 L21SP4_RS05805 0d9e1beb500304d6934160ac6c7a8089 312 SMART SM01400 1 117 3.0E-75 T 22-04-2016 L21SP4_RS05805 0d9e1beb500304d6934160ac6c7a8089 312 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 1 117 4.7E-47 T 22-04-2016 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|UniPathway: UPA00087 L21SP4_RS05805 0d9e1beb500304d6934160ac6c7a8089 312 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 1 309 42.754 T 22-04-2016 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|UniPathway: UPA00087 L21SP4_RS05805 0d9e1beb500304d6934160ac6c7a8089 312 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 1 309 2.2E-110 T 22-04-2016 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|UniPathway: UPA00087 L21SP4_RS05805 0d9e1beb500304d6934160ac6c7a8089 312 Gene3D G3DSA:3.40.50.2020 1 155 1.1E-72 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like L21SP4_RS05805 0d9e1beb500304d6934160ac6c7a8089 312 SUPERFAMILY SSF53271 66 300 8.44E-57 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like L21SP4_RS05805 0d9e1beb500304d6934160ac6c7a8089 312 Gene3D G3DSA:3.40.50.2020 156 276 2.2E-39 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like L21SP4_RS05805 0d9e1beb500304d6934160ac6c7a8089 312 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 125 140 - T 22-04-2016 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: REACT_474|UniPathway: UPA00087 L21SP4_RS05805 0d9e1beb500304d6934160ac6c7a8089 312 PANTHER PTHR10210:SF41 1 312 2.3E-149 T 22-04-2016 L21SP4_RS05805 0d9e1beb500304d6934160ac6c7a8089 312 Pfam PF14572 Phosphoribosyl synthetase-associated domain 203 309 8.6E-21 T 22-04-2016 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|UniPathway: UPA00087 L21SP4_RS05805 0d9e1beb500304d6934160ac6c7a8089 312 PANTHER PTHR10210 1 312 2.3E-149 T 22-04-2016 L21SP4_RS10225 14afc36fd08847c20714a300614b88c9 102 SUPERFAMILY SSF141000 12 98 4.71E-25 T 22-04-2016 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 L21SP4_RS10225 14afc36fd08847c20714a300614b88c9 102 PANTHER PTHR15004 9 101 9.0E-22 T 22-04-2016 L21SP4_RS10225 14afc36fd08847c20714a300614b88c9 102 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 24 95 7.4E-16 T 22-04-2016 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 L21SP4_RS10225 14afc36fd08847c20714a300614b88c9 102 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 10 100 5.3E-25 T 22-04-2016 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 L21SP4_RS10225 14afc36fd08847c20714a300614b88c9 102 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 7 100 21.272 T 22-04-2016 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 L21SP4_RS01290 db1a4789c40b55099092728eda976926 359 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 11 349 1.6E-132 T 22-04-2016 IPR006321 Pilus retraction protein PilT GO:0005524|GO:0006810 L21SP4_RS01290 db1a4789c40b55099092728eda976926 359 SUPERFAMILY SSF52540 9 344 3.81E-65 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS01290 db1a4789c40b55099092728eda976926 359 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 201 215 - T 22-04-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 L21SP4_RS01290 db1a4789c40b55099092728eda976926 359 Pfam PF00437 Type II/IV secretion system protein 84 272 2.7E-43 T 22-04-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 L21SP4_RS01290 db1a4789c40b55099092728eda976926 359 SMART SM00382 130 264 6.6E-6 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS01290 db1a4789c40b55099092728eda976926 359 PANTHER PTHR30486:SF5 11 359 1.8E-133 T 22-04-2016 L21SP4_RS01290 db1a4789c40b55099092728eda976926 359 Gene3D G3DSA:3.40.50.300 111 348 2.5E-68 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS01290 db1a4789c40b55099092728eda976926 359 PANTHER PTHR30486 11 359 1.8E-133 T 22-04-2016 L21SP4_RS06930 f468df07c8d89fb2adde09d7e347c641 431 Pfam PF01189 16S rRNA methyltransferase RsmB/F 243 407 3.5E-44 T 22-04-2016 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 L21SP4_RS06930 f468df07c8d89fb2adde09d7e347c641 431 SUPERFAMILY SSF48013 14 145 5.23E-22 T 22-04-2016 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 L21SP4_RS06930 f468df07c8d89fb2adde09d7e347c641 431 TIGRFAM TIGR00563 rsmB: 16S rRNA (cytosine(967)-C(5))-methyltransferase 41 419 3.6E-84 T 22-04-2016 IPR004573 rRNA small subunit methyltransferase B GO:0006364|GO:0008649 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 L21SP4_RS06930 f468df07c8d89fb2adde09d7e347c641 431 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 371 387 1.17E-24 T 22-04-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 L21SP4_RS06930 f468df07c8d89fb2adde09d7e347c641 431 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 408 425 1.17E-24 T 22-04-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 L21SP4_RS06930 f468df07c8d89fb2adde09d7e347c641 431 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 224 238 1.17E-24 T 22-04-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 L21SP4_RS06930 f468df07c8d89fb2adde09d7e347c641 431 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 321 333 1.17E-24 T 22-04-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 L21SP4_RS06930 f468df07c8d89fb2adde09d7e347c641 431 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 253 263 1.17E-24 T 22-04-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 L21SP4_RS06930 f468df07c8d89fb2adde09d7e347c641 431 Pfam PF01029 NusB family 35 124 5.3E-16 T 22-04-2016 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 L21SP4_RS06930 f468df07c8d89fb2adde09d7e347c641 431 PANTHER PTHR22807 42 387 1.2E-85 T 22-04-2016 L21SP4_RS06930 f468df07c8d89fb2adde09d7e347c641 431 Gene3D G3DSA:3.30.70.1170 177 232 8.7E-4 T 22-04-2016 L21SP4_RS06930 f468df07c8d89fb2adde09d7e347c641 431 Gene3D G3DSA:3.40.50.150 238 425 1.4E-50 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS06930 f468df07c8d89fb2adde09d7e347c641 431 SUPERFAMILY SSF53335 138 425 1.81E-63 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS06930 f468df07c8d89fb2adde09d7e347c641 431 Gene3D G3DSA:1.10.940.10 11 148 1.7E-27 T 22-04-2016 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 L21SP4_RS08395 9b1c244133edba04f5529136daf79b99 94 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 5 94 18.822 T 22-04-2016 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 L21SP4_RS08395 9b1c244133edba04f5529136daf79b99 94 SUPERFAMILY SSF54189 2 91 1.73E-28 T 22-04-2016 IPR012678 Ribosomal protein L23/L15e core domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS08395 9b1c244133edba04f5529136daf79b99 94 Pfam PF00276 Ribosomal protein L23 7 92 3.4E-31 T 22-04-2016 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 L21SP4_RS08395 9b1c244133edba04f5529136daf79b99 94 PANTHER PTHR11620 2 90 1.2E-24 T 22-04-2016 L21SP4_RS08395 9b1c244133edba04f5529136daf79b99 94 Gene3D G3DSA:3.30.70.330 2 93 8.7E-33 T 22-04-2016 IPR012677 Nucleotide-binding alpha-beta plait domain GO:0000166 L21SP4_RS01885 e21ed82e35ae7152cbc202fa403572a7 215 SUPERFAMILY SSF46785 4 73 4.9E-10 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS01885 e21ed82e35ae7152cbc202fa403572a7 215 Gene3D G3DSA:1.10.10.10 3 70 5.7E-19 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS01885 e21ed82e35ae7152cbc202fa403572a7 215 Hamap MF_01131 Redox-sensing transcriptional repressor Rex [rex]. 1 203 27.53 T 22-04-2016 IPR022876 Redox-sensing transcriptional repressor Rex GO:0005737|GO:0045892|GO:0051775 L21SP4_RS01885 e21ed82e35ae7152cbc202fa403572a7 215 Gene3D G3DSA:3.40.50.720 73 205 6.5E-37 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS01885 e21ed82e35ae7152cbc202fa403572a7 215 PANTHER PTHR35786:SF1 5 209 1.2E-60 T 22-04-2016 L21SP4_RS01885 e21ed82e35ae7152cbc202fa403572a7 215 Pfam PF06971 Putative DNA-binding protein N-terminus 3 48 4.7E-12 T 22-04-2016 IPR009718 Rex DNA-binding, C-terminal domain GO:0005737|GO:0045892|GO:0051775 L21SP4_RS01885 e21ed82e35ae7152cbc202fa403572a7 215 Pfam PF02629 CoA binding domain 77 172 1.1E-11 T 22-04-2016 IPR003781 CoA-binding GO:0048037 L21SP4_RS01885 e21ed82e35ae7152cbc202fa403572a7 215 SMART SM00881 74 174 1.7E-9 T 22-04-2016 IPR003781 CoA-binding GO:0048037 L21SP4_RS01885 e21ed82e35ae7152cbc202fa403572a7 215 PANTHER PTHR35786 5 209 1.2E-60 T 22-04-2016 L21SP4_RS01885 e21ed82e35ae7152cbc202fa403572a7 215 SUPERFAMILY SSF51735 77 199 8.96E-21 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS06650 81cf1dfcecc536d87e6efb968ef321e6 410 Pfam PF01609 Transposase DDE domain 130 346 4.3E-24 T 22-04-2016 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 L21SP4_RS06650 81cf1dfcecc536d87e6efb968ef321e6 410 Pfam PF14294 Domain of unknown function (DUF4372) 10 71 2.3E-11 T 22-04-2016 IPR025399 Domain of unknown function DUF4372 L21SP4_RS06650 81cf1dfcecc536d87e6efb968ef321e6 410 Gene3D G3DSA:3.90.350.10 293 321 1.1E-4 T 22-04-2016 IPR014736 Transposase, Tn5-like, core L21SP4_RS06650 81cf1dfcecc536d87e6efb968ef321e6 410 PANTHER PTHR33258 8 382 5.9E-35 T 22-04-2016 L21SP4_RS06650 81cf1dfcecc536d87e6efb968ef321e6 410 PANTHER PTHR33258:SF1 8 382 5.9E-35 T 22-04-2016 L21SP4_RS06650 81cf1dfcecc536d87e6efb968ef321e6 410 SUPERFAMILY SSF53098 128 367 1.21E-22 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS06655 fa3a33493827c8967a404ee865046547 331 Pfam PF00356 Bacterial regulatory proteins, lacI family 2 34 1.5E-4 T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 L21SP4_RS06655 fa3a33493827c8967a404ee865046547 331 Pfam PF13377 Periplasmic binding protein-like domain 172 327 1.8E-18 T 22-04-2016 L21SP4_RS06655 fa3a33493827c8967a404ee865046547 331 Gene3D G3DSA:3.40.50.2300 173 309 9.6E-24 T 22-04-2016 L21SP4_RS06655 fa3a33493827c8967a404ee865046547 331 SUPERFAMILY SSF47413 2 41 4.5E-5 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 L21SP4_RS06655 fa3a33493827c8967a404ee865046547 331 Gene3D G3DSA:3.40.50.2300 70 172 1.3E-7 T 22-04-2016 L21SP4_RS06655 fa3a33493827c8967a404ee865046547 331 SUPERFAMILY SSF53822 73 327 5.78E-29 T 22-04-2016 IPR028082 Periplasmic binding protein-like I L21SP4_RS06655 fa3a33493827c8967a404ee865046547 331 Gene3D G3DSA:1.10.260.40 2 34 2.0E-7 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 L21SP4_RS06655 fa3a33493827c8967a404ee865046547 331 PANTHER PTHR30146 2 326 2.9E-30 T 22-04-2016 L21SP4_RS04330 3c8c94c6a28199d47dbcd5526fe67275 364 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 4 360 2.9E-145 T 22-04-2016 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 L21SP4_RS04330 3c8c94c6a28199d47dbcd5526fe67275 364 PANTHER PTHR11405 2 362 4.4E-214 T 22-04-2016 L21SP4_RS04330 3c8c94c6a28199d47dbcd5526fe67275 364 Pfam PF00117 Glutamine amidotransferase class-I 181 357 1.4E-44 T 22-04-2016 IPR017926 Glutamine amidotransferase Reactome: REACT_1698 L21SP4_RS04330 3c8c94c6a28199d47dbcd5526fe67275 364 SMART SM01097 1 131 4.5E-88 T 22-04-2016 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 L21SP4_RS04330 3c8c94c6a28199d47dbcd5526fe67275 364 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 3 130 3.3E-52 T 22-04-2016 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 L21SP4_RS04330 3c8c94c6a28199d47dbcd5526fe67275 364 SUPERFAMILY SSF52021 2 148 2.88E-57 T 22-04-2016 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 L21SP4_RS04330 3c8c94c6a28199d47dbcd5526fe67275 364 PRINTS PR00096 Glutamine amidotransferase superfamily signature 249 260 7.0E-12 T 22-04-2016 L21SP4_RS04330 3c8c94c6a28199d47dbcd5526fe67275 364 PRINTS PR00096 Glutamine amidotransferase superfamily signature 221 230 7.0E-12 T 22-04-2016 L21SP4_RS04330 3c8c94c6a28199d47dbcd5526fe67275 364 PRINTS PR00096 Glutamine amidotransferase superfamily signature 334 347 7.0E-12 T 22-04-2016 L21SP4_RS04330 3c8c94c6a28199d47dbcd5526fe67275 364 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 179 193 2.1E-36 T 22-04-2016 L21SP4_RS04330 3c8c94c6a28199d47dbcd5526fe67275 364 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 266 283 2.1E-36 T 22-04-2016 L21SP4_RS04330 3c8c94c6a28199d47dbcd5526fe67275 364 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 218 232 2.1E-36 T 22-04-2016 L21SP4_RS04330 3c8c94c6a28199d47dbcd5526fe67275 364 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 249 265 2.1E-36 T 22-04-2016 L21SP4_RS04330 3c8c94c6a28199d47dbcd5526fe67275 364 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 291 302 2.1E-36 T 22-04-2016 L21SP4_RS04330 3c8c94c6a28199d47dbcd5526fe67275 364 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 1 363 47.119 T 22-04-2016 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 L21SP4_RS04330 3c8c94c6a28199d47dbcd5526fe67275 364 Gene3D G3DSA:3.50.30.20 2 146 1.0E-58 T 22-04-2016 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 L21SP4_RS04330 3c8c94c6a28199d47dbcd5526fe67275 364 PRINTS PR00097 Anthranilate synthase component II signature 334 347 1.0E-6 T 22-04-2016 L21SP4_RS04330 3c8c94c6a28199d47dbcd5526fe67275 364 PRINTS PR00097 Anthranilate synthase component II signature 221 230 1.0E-6 T 22-04-2016 L21SP4_RS04330 3c8c94c6a28199d47dbcd5526fe67275 364 PRINTS PR00097 Anthranilate synthase component II signature 249 260 1.0E-6 T 22-04-2016 L21SP4_RS04330 3c8c94c6a28199d47dbcd5526fe67275 364 SUPERFAMILY SSF52317 172 361 3.7E-59 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like L21SP4_RS04330 3c8c94c6a28199d47dbcd5526fe67275 364 Gene3D G3DSA:3.40.50.880 152 361 3.0E-72 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like L21SP4_RS09905 d9a3a2d76a5c7600815517a031db662b 443 Hamap MF_00712 Probable glycine dehydrogenase (decarboxylating) subunit 1 [gcvPA]. 1 442 44.191 T 22-04-2016 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 L21SP4_RS09905 d9a3a2d76a5c7600815517a031db662b 443 PANTHER PTHR11773:SF2 1 441 3.4E-194 T 22-04-2016 L21SP4_RS09905 d9a3a2d76a5c7600815517a031db662b 443 Gene3D G3DSA:3.40.640.10 58 294 7.9E-25 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 L21SP4_RS09905 d9a3a2d76a5c7600815517a031db662b 443 Pfam PF02347 Glycine cleavage system P-protein 2 436 1.4E-123 T 22-04-2016 IPR020580 Glycine cleavage system P-protein, N-terminal GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2 L21SP4_RS09905 d9a3a2d76a5c7600815517a031db662b 443 PANTHER PTHR11773 1 441 3.4E-194 T 22-04-2016 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2 L21SP4_RS09905 d9a3a2d76a5c7600815517a031db662b 443 PIRSF PIRSF006815 1 443 2.8E-173 T 22-04-2016 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 L21SP4_RS09905 d9a3a2d76a5c7600815517a031db662b 443 SUPERFAMILY SSF53383 1 442 3.54E-115 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase L21SP4_RS10060 5d18df64b92b0a6bd0aea5683f7d1225 259 Pfam PF13242 HAD-hyrolase-like 182 253 2.1E-22 T 22-04-2016 L21SP4_RS10060 5d18df64b92b0a6bd0aea5683f7d1225 259 SUPERFAMILY SSF56784 7 254 2.8E-67 T 22-04-2016 IPR023214 HAD-like domain L21SP4_RS10060 5d18df64b92b0a6bd0aea5683f7d1225 259 PANTHER PTHR19288:SF40 7 254 6.1E-117 T 22-04-2016 L21SP4_RS10060 5d18df64b92b0a6bd0aea5683f7d1225 259 PIRSF PIRSF000915 3 257 1.1E-53 T 22-04-2016 IPR006357 HAD-superfamily hydrolase, subfamily IIA L21SP4_RS10060 5d18df64b92b0a6bd0aea5683f7d1225 259 Gene3D G3DSA:3.40.50.1000 5 78 2.1E-44 T 22-04-2016 IPR023214 HAD-like domain L21SP4_RS10060 5d18df64b92b0a6bd0aea5683f7d1225 259 Gene3D G3DSA:3.40.50.1000 180 254 2.1E-44 T 22-04-2016 IPR023214 HAD-like domain L21SP4_RS10060 5d18df64b92b0a6bd0aea5683f7d1225 259 Pfam PF13344 Haloacid dehalogenase-like hydrolase 9 108 8.3E-28 T 22-04-2016 IPR006357 HAD-superfamily hydrolase, subfamily IIA L21SP4_RS10060 5d18df64b92b0a6bd0aea5683f7d1225 259 PANTHER PTHR19288 7 254 6.1E-117 T 22-04-2016 L21SP4_RS10060 5d18df64b92b0a6bd0aea5683f7d1225 259 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 9 230 1.2E-47 T 22-04-2016 IPR006357 HAD-superfamily hydrolase, subfamily IIA L21SP4_RS10060 5d18df64b92b0a6bd0aea5683f7d1225 259 Gene3D G3DSA:3.40.50.10410 79 179 2.9E-29 T 22-04-2016 IPR023215 Nitrophenylphosphatase-like domain L21SP4_RS01110 de2b8ec45615f35f9fcea069798d885f 399 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 92 101 - T 22-04-2016 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 L21SP4_RS01110 de2b8ec45615f35f9fcea069798d885f 399 Gene3D G3DSA:3.40.630.10 309 391 4.0E-27 T 22-04-2016 L21SP4_RS01110 de2b8ec45615f35f9fcea069798d885f 399 Gene3D G3DSA:3.40.630.10 32 197 4.0E-27 T 22-04-2016 L21SP4_RS01110 de2b8ec45615f35f9fcea069798d885f 399 Pfam PF07687 Peptidase dimerisation domain 220 294 1.3E-7 T 22-04-2016 IPR011650 Peptidase M20, dimerisation domain L21SP4_RS01110 de2b8ec45615f35f9fcea069798d885f 399 Gene3D G3DSA:3.30.70.360 220 304 1.7E-13 T 22-04-2016 IPR011650 Peptidase M20, dimerisation domain L21SP4_RS01110 de2b8ec45615f35f9fcea069798d885f 399 SUPERFAMILY SSF53187 39 210 4.92E-26 T 22-04-2016 L21SP4_RS01110 de2b8ec45615f35f9fcea069798d885f 399 SUPERFAMILY SSF53187 306 391 4.92E-26 T 22-04-2016 L21SP4_RS01110 de2b8ec45615f35f9fcea069798d885f 399 Pfam PF01546 Peptidase family M20/M25/M40 94 387 5.2E-6 T 22-04-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 L21SP4_RS01110 de2b8ec45615f35f9fcea069798d885f 399 PANTHER PTHR11014 41 390 4.0E-15 T 22-04-2016 L21SP4_RS01110 de2b8ec45615f35f9fcea069798d885f 399 SUPERFAMILY SSF55031 220 310 8.72E-12 T 22-04-2016 IPR011650 Peptidase M20, dimerisation domain L21SP4_RS07825 d30fcb4961c9307744f66ba68e703fd8 356 SUPERFAMILY SSF143555 211 311 2.35E-5 T 22-04-2016 L21SP4_RS10820 2197a2fb0880e095b64a3d41a0def00c 714 Gene3D G3DSA:3.40.50.1820 15 258 1.8E-45 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold L21SP4_RS10820 2197a2fb0880e095b64a3d41a0def00c 714 SUPERFAMILY SSF53474 17 263 2.41E-40 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold L21SP4_RS10820 2197a2fb0880e095b64a3d41a0def00c 714 Pfam PF00135 Carboxylesterase family 23 139 4.0E-19 T 22-04-2016 IPR002018 Carboxylesterase, type B L21SP4_RS10820 2197a2fb0880e095b64a3d41a0def00c 714 PANTHER PTHR23024 28 221 1.5E-24 T 22-04-2016 L21SP4_RS00075 92fd348334c8336c1664f8ea51e9817d 336 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 10 336 43.945 T 22-04-2016 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 L21SP4_RS00075 92fd348334c8336c1664f8ea51e9817d 336 SUPERFAMILY SSF55681 93 336 4.21E-76 T 22-04-2016 L21SP4_RS00075 92fd348334c8336c1664f8ea51e9817d 336 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 24 84 1.6E-21 T 22-04-2016 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 L21SP4_RS00075 92fd348334c8336c1664f8ea51e9817d 336 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 41 336 3.6E-96 T 22-04-2016 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 L21SP4_RS00075 92fd348334c8336c1664f8ea51e9817d 336 Pfam PF01409 tRNA synthetases class II core domain (F) 97 336 1.2E-97 T 22-04-2016 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 L21SP4_RS00075 92fd348334c8336c1664f8ea51e9817d 336 PANTHER PTHR11538 101 336 1.2E-98 T 22-04-2016 L21SP4_RS00075 92fd348334c8336c1664f8ea51e9817d 336 SUPERFAMILY SSF46589 15 83 3.56E-14 T 22-04-2016 IPR010978 tRNA-binding arm GO:0000166 Reactome: REACT_71 L21SP4_RS00075 92fd348334c8336c1664f8ea51e9817d 336 Gene3D G3DSA:3.30.930.10 12 336 2.5E-118 T 22-04-2016 L21SP4_RS00510 fec948b5020cd241b722e178388c3a0a 75 SUPERFAMILY SSF54565 2 74 1.31E-24 T 22-04-2016 IPR023803 Ribosomal protein S16 domain L21SP4_RS00510 fec948b5020cd241b722e178388c3a0a 75 Gene3D G3DSA:3.30.1320.10 2 74 2.7E-25 T 22-04-2016 IPR023803 Ribosomal protein S16 domain L21SP4_RS00510 fec948b5020cd241b722e178388c3a0a 75 PANTHER PTHR12919 2 75 1.6E-25 T 22-04-2016 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS00510 fec948b5020cd241b722e178388c3a0a 75 Pfam PF00886 Ribosomal protein S16 9 67 1.1E-20 T 22-04-2016 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS00510 fec948b5020cd241b722e178388c3a0a 75 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 2 75 18.318 T 22-04-2016 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS00510 fec948b5020cd241b722e178388c3a0a 75 TIGRFAM TIGR00002 S16: ribosomal protein bS16 3 74 1.6E-24 T 22-04-2016 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS02905 7bd92bedc8ea468292592899ab54866e 252 SUPERFAMILY SSF51366 2 251 2.9E-82 T 22-04-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 L21SP4_RS02905 7bd92bedc8ea468292592899ab54866e 252 Pfam PF00977 Histidine biosynthesis protein 5 235 3.0E-87 T 22-04-2016 IPR006062 Histidine biosynthesis GO:0000105 L21SP4_RS02905 7bd92bedc8ea468292592899ab54866e 252 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 1 251 48.084 T 22-04-2016 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 UniPathway: UPA00031 L21SP4_RS02905 7bd92bedc8ea468292592899ab54866e 252 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 2 251 1.2E-111 T 22-04-2016 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 UniPathway: UPA00031 L21SP4_RS02905 7bd92bedc8ea468292592899ab54866e 252 Gene3D G3DSA:3.20.20.70 4 252 1.0E-103 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP4_RS02905 7bd92bedc8ea468292592899ab54866e 252 PANTHER PTHR21235:SF2 2 252 3.5E-119 T 22-04-2016 L21SP4_RS02905 7bd92bedc8ea468292592899ab54866e 252 PANTHER PTHR21235 2 252 3.5E-119 T 22-04-2016 L21SP4_RS01435 7c643b710533fcdbec50fcf672367ca5 449 SUPERFAMILY SSF161098 196 434 7.72E-36 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 L21SP4_RS01435 7c643b710533fcdbec50fcf672367ca5 449 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 199 443 2.7E-82 T 22-04-2016 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 L21SP4_RS01435 7c643b710533fcdbec50fcf672367ca5 449 PANTHER PTHR30425 184 449 5.9E-82 T 22-04-2016 L21SP4_RS01435 7c643b710533fcdbec50fcf672367ca5 449 Gene3D G3DSA:1.10.3720.10 199 444 1.5E-46 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 L21SP4_RS01435 7c643b710533fcdbec50fcf672367ca5 449 Gene3D G3DSA:1.10.3720.10 19 45 1.5E-46 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 L21SP4_RS01435 7c643b710533fcdbec50fcf672367ca5 449 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 239 448 4.2E-29 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 L21SP4_RS04090 f16b0832ad180391dc56e33953682901 138 Pfam PF02472 Biopolymer transport protein ExbD/TolR 4 135 7.6E-20 T 22-04-2016 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 L21SP4_RS04090 f16b0832ad180391dc56e33953682901 138 PANTHER PTHR30558 3 133 1.7E-16 T 22-04-2016 L21SP4_RS02010 f60a3938af0833c057e9300300f31e8c 495 Pfam PF00884 Sulfatase 31 332 7.8E-47 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS02010 f60a3938af0833c057e9300300f31e8c 495 Gene3D G3DSA:3.30.1120.10 379 394 5.2E-14 T 22-04-2016 L21SP4_RS02010 f60a3938af0833c057e9300300f31e8c 495 Gene3D G3DSA:3.30.1120.10 431 478 5.2E-14 T 22-04-2016 L21SP4_RS02010 f60a3938af0833c057e9300300f31e8c 495 Gene3D G3DSA:3.40.720.10 32 200 2.7E-63 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS02010 f60a3938af0833c057e9300300f31e8c 495 Gene3D G3DSA:3.40.720.10 237 378 2.7E-63 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS02010 f60a3938af0833c057e9300300f31e8c 495 PANTHER PTHR10342 425 475 5.2E-76 T 22-04-2016 L21SP4_RS02010 f60a3938af0833c057e9300300f31e8c 495 PANTHER PTHR10342 3 408 5.2E-76 T 22-04-2016 L21SP4_RS02010 f60a3938af0833c057e9300300f31e8c 495 SUPERFAMILY SSF53649 429 474 8.43E-89 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS02010 f60a3938af0833c057e9300300f31e8c 495 SUPERFAMILY SSF53649 32 392 8.43E-89 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS02585 0429fb2699533d287ddf989734dff15d 180 PANTHER PTHR22573 1 172 2.0E-53 T 22-04-2016 L21SP4_RS02585 0429fb2699533d287ddf989734dff15d 180 Pfam PF00156 Phosphoribosyl transferase domain 10 163 1.8E-17 T 22-04-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 L21SP4_RS02585 0429fb2699533d287ddf989734dff15d 180 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 9 175 1.8E-47 T 22-04-2016 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620|UniPathway: UPA00591 L21SP4_RS02585 0429fb2699533d287ddf989734dff15d 180 Gene3D G3DSA:3.40.50.2020 4 174 2.2E-56 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like L21SP4_RS02585 0429fb2699533d287ddf989734dff15d 180 SUPERFAMILY SSF53271 4 173 3.07E-46 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like L21SP4_RS02585 0429fb2699533d287ddf989734dff15d 180 PANTHER PTHR22573:SF56 1 172 2.0E-53 T 22-04-2016 L21SP4_RS12035 d67bdc27fd9ce06417b99c8819e0c0b5 333 SUPERFAMILY SSF53098 121 290 3.19E-41 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS12035 d67bdc27fd9ce06417b99c8819e0c0b5 333 Gene3D G3DSA:3.30.420.10 117 278 1.0E-29 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS12035 d67bdc27fd9ce06417b99c8819e0c0b5 333 SUPERFAMILY SSF46689 10 98 4.21E-7 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS12035 d67bdc27fd9ce06417b99c8819e0c0b5 333 Pfam PF00665 Integrase core domain 122 240 2.2E-25 T 22-04-2016 IPR001584 Integrase, catalytic core GO:0015074 L21SP4_RS12035 d67bdc27fd9ce06417b99c8819e0c0b5 333 Pfam PF13384 Homeodomain-like domain 10 33 1.2E-6 T 22-04-2016 L21SP4_RS12035 d67bdc27fd9ce06417b99c8819e0c0b5 333 PANTHER PTHR32552 11 282 1.0E-31 T 22-04-2016 L21SP4_RS12035 d67bdc27fd9ce06417b99c8819e0c0b5 333 Gene3D G3DSA:1.10.10.700 6 36 3.6E-4 T 22-04-2016 L21SP4_RS12065 6a4be11d6038bca727ecc886ae7fcc39 320 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 50 4.9E-11 T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 L21SP4_RS12065 6a4be11d6038bca727ecc886ae7fcc39 320 SUPERFAMILY SSF47413 2 60 3.17E-14 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 L21SP4_RS12065 6a4be11d6038bca727ecc886ae7fcc39 320 Gene3D G3DSA:3.40.50.2300 54 189 8.6E-19 T 22-04-2016 L21SP4_RS12065 6a4be11d6038bca727ecc886ae7fcc39 320 SMART SM00354 3 73 2.7E-11 T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 L21SP4_RS12065 6a4be11d6038bca727ecc886ae7fcc39 320 SUPERFAMILY SSF53822 60 212 1.3E-16 T 22-04-2016 IPR028082 Periplasmic binding protein-like I L21SP4_RS12065 6a4be11d6038bca727ecc886ae7fcc39 320 Gene3D G3DSA:1.10.260.40 3 53 1.1E-17 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 L21SP4_RS12065 6a4be11d6038bca727ecc886ae7fcc39 320 PANTHER PTHR30146 3 210 1.6E-37 T 22-04-2016 L21SP4_RS08480 c7f20999c9f9bf63f8a2d6a798d7257b 401 Pfam PF03143 Elongation factor Tu C-terminal domain 305 399 1.5E-34 T 22-04-2016 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal L21SP4_RS08480 c7f20999c9f9bf63f8a2d6a798d7257b 401 Pfam PF00009 Elongation factor Tu GTP binding domain 10 208 3.2E-52 T 22-04-2016 L21SP4_RS08480 c7f20999c9f9bf63f8a2d6a798d7257b 401 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 401 2.8E-214 T 22-04-2016 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 L21SP4_RS08480 c7f20999c9f9bf63f8a2d6a798d7257b 401 Gene3D G3DSA:2.40.30.10 219 305 1.3E-35 T 22-04-2016 L21SP4_RS08480 c7f20999c9f9bf63f8a2d6a798d7257b 401 Gene3D G3DSA:2.40.30.10 307 399 1.3E-46 T 22-04-2016 L21SP4_RS08480 c7f20999c9f9bf63f8a2d6a798d7257b 401 PRINTS PR00315 GTP-binding elongation factor signature 83 93 5.8E-20 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 L21SP4_RS08480 c7f20999c9f9bf63f8a2d6a798d7257b 401 PRINTS PR00315 GTP-binding elongation factor signature 99 110 5.8E-20 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 L21SP4_RS08480 c7f20999c9f9bf63f8a2d6a798d7257b 401 PRINTS PR00315 GTP-binding elongation factor signature 136 145 5.8E-20 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 L21SP4_RS08480 c7f20999c9f9bf63f8a2d6a798d7257b 401 PRINTS PR00315 GTP-binding elongation factor signature 14 27 5.8E-20 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 L21SP4_RS08480 c7f20999c9f9bf63f8a2d6a798d7257b 401 SUPERFAMILY SSF50447 214 308 4.71E-29 T 22-04-2016 IPR009000 Translation protein, beta-barrel domain L21SP4_RS08480 c7f20999c9f9bf63f8a2d6a798d7257b 401 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 401 58.764 T 22-04-2016 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 L21SP4_RS08480 c7f20999c9f9bf63f8a2d6a798d7257b 401 Pfam PF03144 Elongation factor Tu domain 2 232 300 1.2E-17 T 22-04-2016 IPR004161 Translation elongation factor EFTu/EF1A, domain 2 GO:0005525 L21SP4_RS08480 c7f20999c9f9bf63f8a2d6a798d7257b 401 PANTHER PTHR23115:SF151 1 399 3.3E-233 T 22-04-2016 L21SP4_RS08480 c7f20999c9f9bf63f8a2d6a798d7257b 401 SUPERFAMILY SSF50465 305 400 1.87E-36 T 22-04-2016 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal L21SP4_RS08480 c7f20999c9f9bf63f8a2d6a798d7257b 401 Gene3D G3DSA:3.40.50.300 4 218 2.5E-62 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS08480 c7f20999c9f9bf63f8a2d6a798d7257b 401 SUPERFAMILY SSF52540 6 226 9.74E-56 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS08480 c7f20999c9f9bf63f8a2d6a798d7257b 401 PANTHER PTHR23115 1 399 3.3E-233 T 22-04-2016 L21SP4_RS08480 c7f20999c9f9bf63f8a2d6a798d7257b 401 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 150 8.9E-18 T 22-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 L21SP4_RS04955 dd4e9ad528d4b434b22bf6d2bd49751b 514 PANTHER PTHR22550:SF8 1 259 1.9E-31 T 22-04-2016 L21SP4_RS04955 dd4e9ad528d4b434b22bf6d2bd49751b 514 SUPERFAMILY SSF53300 247 260 7.86E-21 T 22-04-2016 IPR002035 von Willebrand factor, type A L21SP4_RS04955 dd4e9ad528d4b434b22bf6d2bd49751b 514 SUPERFAMILY SSF53300 80 219 7.86E-21 T 22-04-2016 IPR002035 von Willebrand factor, type A L21SP4_RS04955 dd4e9ad528d4b434b22bf6d2bd49751b 514 Pfam PF13519 von Willebrand factor type A domain 83 192 6.4E-17 T 22-04-2016 IPR002035 von Willebrand factor, type A L21SP4_RS04955 dd4e9ad528d4b434b22bf6d2bd49751b 514 PANTHER PTHR22550 1 259 1.9E-31 T 22-04-2016 L21SP4_RS04955 dd4e9ad528d4b434b22bf6d2bd49751b 514 SMART SM00327 80 256 8.7E-13 T 22-04-2016 IPR002035 von Willebrand factor, type A L21SP4_RS04955 dd4e9ad528d4b434b22bf6d2bd49751b 514 Gene3D G3DSA:3.40.50.410 81 247 1.4E-13 T 22-04-2016 IPR002035 von Willebrand factor, type A L21SP4_RS10645 f31cfdd0f2d405a26fd7b423b6706903 379 Pfam PF02684 Lipid-A-disaccharide synthetase 7 345 8.8E-86 T 22-04-2016 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622|UniPathway: UPA00359 L21SP4_RS10645 f31cfdd0f2d405a26fd7b423b6706903 379 Gene3D G3DSA:3.40.50.2000 158 351 6.3E-7 T 22-04-2016 L21SP4_RS10645 f31cfdd0f2d405a26fd7b423b6706903 379 TIGRFAM TIGR00215 lpxB: lipid-A-disaccharide synthase 6 356 4.7E-78 T 22-04-2016 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622|UniPathway: UPA00359 L21SP4_RS10645 f31cfdd0f2d405a26fd7b423b6706903 379 PANTHER PTHR30372:SF0 7 355 1.5E-88 T 22-04-2016 L21SP4_RS10645 f31cfdd0f2d405a26fd7b423b6706903 379 PANTHER PTHR30372 7 355 1.5E-88 T 22-04-2016 L21SP4_RS10645 f31cfdd0f2d405a26fd7b423b6706903 379 SUPERFAMILY SSF53756 6 356 3.77E-24 T 22-04-2016 L21SP4_RS05450 50f1a268aaf381594781ebdbdddf1196 776 SUPERFAMILY SSF51621 444 727 2.38E-92 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 L21SP4_RS05450 50f1a268aaf381594781ebdbdddf1196 776 SMART SM00065 25 172 3.0E-19 T 22-04-2016 IPR003018 GAF domain GO:0005515 L21SP4_RS05450 50f1a268aaf381594781ebdbdddf1196 776 Gene3D G3DSA:3.30.450.40 13 176 1.7E-38 T 22-04-2016 IPR029016 GAF domain-like L21SP4_RS05450 50f1a268aaf381594781ebdbdddf1196 776 SUPERFAMILY SSF47831 228 331 5.1E-22 T 22-04-2016 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 L21SP4_RS05450 50f1a268aaf381594781ebdbdddf1196 776 Gene3D G3DSA:1.10.274.10 229 322 7.5E-25 T 22-04-2016 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 L21SP4_RS05450 50f1a268aaf381594781ebdbdddf1196 776 Gene3D G3DSA:3.20.20.60 442 754 6.6E-97 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 L21SP4_RS05450 50f1a268aaf381594781ebdbdddf1196 776 Pfam PF00391 PEP-utilising enzyme, mobile domain 341 411 7.8E-10 T 22-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 L21SP4_RS05450 50f1a268aaf381594781ebdbdddf1196 776 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 191 750 3.9E-140 T 22-04-2016 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 L21SP4_RS05450 50f1a268aaf381594781ebdbdddf1196 776 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 443 725 1.3E-93 T 22-04-2016 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 L21SP4_RS05450 50f1a268aaf381594781ebdbdddf1196 776 SUPERFAMILY SSF52009 313 431 1.7E-21 T 22-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 L21SP4_RS05450 50f1a268aaf381594781ebdbdddf1196 776 Pfam PF13185 GAF domain 24 163 7.7E-18 T 22-04-2016 IPR003018 GAF domain GO:0005515 L21SP4_RS05450 50f1a268aaf381594781ebdbdddf1196 776 PANTHER PTHR22931:SF28 222 735 3.3E-132 T 22-04-2016 L21SP4_RS05450 50f1a268aaf381594781ebdbdddf1196 776 Gene3D G3DSA:3.50.30.10 323 433 3.7E-22 T 22-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 L21SP4_RS05450 50f1a268aaf381594781ebdbdddf1196 776 SUPERFAMILY SSF55781 13 167 1.7E-28 T 22-04-2016 IPR029016 GAF domain-like L21SP4_RS05450 50f1a268aaf381594781ebdbdddf1196 776 PANTHER PTHR22931 222 735 3.3E-132 T 22-04-2016 L21SP4_RS05450 50f1a268aaf381594781ebdbdddf1196 776 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 685 697 7.8E-21 T 22-04-2016 L21SP4_RS05450 50f1a268aaf381594781ebdbdddf1196 776 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 632 647 7.8E-21 T 22-04-2016 L21SP4_RS05450 50f1a268aaf381594781ebdbdddf1196 776 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 478 497 7.8E-21 T 22-04-2016 L21SP4_RS05450 50f1a268aaf381594781ebdbdddf1196 776 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 649 664 7.8E-21 T 22-04-2016 L21SP4_RS05450 50f1a268aaf381594781ebdbdddf1196 776 Pfam PF05524 PEP-utilising enzyme, N-terminal 192 313 4.2E-20 T 22-04-2016 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 L21SP4_RS05420 c5d12a8334d73ca97745938f84dee129 141 Pfam PF02472 Biopolymer transport protein ExbD/TolR 8 133 3.7E-27 T 22-04-2016 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 L21SP4_RS05420 c5d12a8334d73ca97745938f84dee129 141 PANTHER PTHR30558:SF3 1 141 6.5E-27 T 22-04-2016 L21SP4_RS05420 c5d12a8334d73ca97745938f84dee129 141 PANTHER PTHR30558 1 141 6.5E-27 T 22-04-2016 L21SP4_RS08385 b66abb3d0e45a0c54b6418f2605601b4 94 SUPERFAMILY SSF54570 3 84 1.44E-32 T 22-04-2016 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 L21SP4_RS08385 b66abb3d0e45a0c54b6418f2605601b4 94 PIRSF PIRSF002144 1 94 8.6E-31 T 22-04-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 L21SP4_RS08385 b66abb3d0e45a0c54b6418f2605601b4 94 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 24.28 T 22-04-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 L21SP4_RS08385 b66abb3d0e45a0c54b6418f2605601b4 94 Pfam PF00203 Ribosomal protein S19 3 83 2.7E-34 T 22-04-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 L21SP4_RS08385 b66abb3d0e45a0c54b6418f2605601b4 94 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 8.7E-21 T 22-04-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 L21SP4_RS08385 b66abb3d0e45a0c54b6418f2605601b4 94 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 8.7E-21 T 22-04-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 L21SP4_RS08385 b66abb3d0e45a0c54b6418f2605601b4 94 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 8.7E-21 T 22-04-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 L21SP4_RS08385 b66abb3d0e45a0c54b6418f2605601b4 94 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 22-04-2016 IPR020934 Ribosomal protein S19 conserved site GO:0003723 L21SP4_RS08385 b66abb3d0e45a0c54b6418f2605601b4 94 PANTHER PTHR11880 1 84 1.5E-42 T 22-04-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 L21SP4_RS08385 b66abb3d0e45a0c54b6418f2605601b4 94 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 88 2.6E-40 T 22-04-2016 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 L21SP4_RS08385 b66abb3d0e45a0c54b6418f2605601b4 94 Gene3D G3DSA:3.30.860.10 1 89 3.3E-37 T 22-04-2016 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 L21SP4_RS08045 14448a98bad9b172dde82d0d89da0e0c 571 Pfam PF00437 Type II/IV secretion system protein 186 454 1.2E-81 T 22-04-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 L21SP4_RS08045 14448a98bad9b172dde82d0d89da0e0c 571 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 382 396 - T 22-04-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 L21SP4_RS08045 14448a98bad9b172dde82d0d89da0e0c 571 SUPERFAMILY SSF52540 162 562 1.36E-104 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS08045 14448a98bad9b172dde82d0d89da0e0c 571 PANTHER PTHR30258:SF2 12 571 1.2E-207 T 22-04-2016 L21SP4_RS08045 14448a98bad9b172dde82d0d89da0e0c 571 Gene3D G3DSA:3.30.450.90 152 287 7.3E-49 T 22-04-2016 L21SP4_RS08045 14448a98bad9b172dde82d0d89da0e0c 571 Gene3D G3DSA:3.40.50.300 292 566 2.1E-99 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS08045 14448a98bad9b172dde82d0d89da0e0c 571 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 43 144 1.3E-18 T 22-04-2016 IPR007831 General secretory system II, protein E, N-terminal GO:0005524|GO:0006810 L21SP4_RS08045 14448a98bad9b172dde82d0d89da0e0c 571 PANTHER PTHR30258 12 571 1.2E-207 T 22-04-2016 L21SP4_RS08045 14448a98bad9b172dde82d0d89da0e0c 571 SUPERFAMILY SSF160246 11 143 6.28E-27 T 22-04-2016 L21SP4_RS02065 8c23bbe1f083ba58c6efcfbfb085406e 850 Gene3D G3DSA:2.60.40.320 177 312 3.8E-17 T 22-04-2016 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 L21SP4_RS02065 8c23bbe1f083ba58c6efcfbfb085406e 850 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 5 132 4.9E-8 T 22-04-2016 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP4_RS02065 8c23bbe1f083ba58c6efcfbfb085406e 850 SUPERFAMILY SSF49303 664 750 2.45E-9 T 22-04-2016 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 L21SP4_RS02065 8c23bbe1f083ba58c6efcfbfb085406e 850 Gene3D G3DSA:3.20.20.80 597 663 3.7E-50 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP4_RS02065 8c23bbe1f083ba58c6efcfbfb085406e 850 Gene3D G3DSA:3.20.20.80 313 551 3.7E-50 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP4_RS02065 8c23bbe1f083ba58c6efcfbfb085406e 850 Gene3D G3DSA:2.60.120.260 3 176 1.5E-29 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS02065 8c23bbe1f083ba58c6efcfbfb085406e 850 SUPERFAMILY SSF49303 773 831 6.91E-8 T 22-04-2016 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 L21SP4_RS02065 8c23bbe1f083ba58c6efcfbfb085406e 850 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 390 453 9.3E-8 T 22-04-2016 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP4_RS02065 8c23bbe1f083ba58c6efcfbfb085406e 850 SUPERFAMILY SSF49785 2 188 7.05E-47 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS02065 8c23bbe1f083ba58c6efcfbfb085406e 850 SUPERFAMILY SSF51445 310 661 1.06E-74 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily L21SP4_RS02065 8c23bbe1f083ba58c6efcfbfb085406e 850 PANTHER PTHR10066 155 703 9.6E-131 T 22-04-2016 L21SP4_RS02065 8c23bbe1f083ba58c6efcfbfb085406e 850 PANTHER PTHR10066 1 137 9.6E-131 T 22-04-2016 L21SP4_RS02065 8c23bbe1f083ba58c6efcfbfb085406e 850 SUPERFAMILY SSF49303 230 312 5.4E-14 T 22-04-2016 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 L21SP4_RS02065 8c23bbe1f083ba58c6efcfbfb085406e 850 Pfam PF00703 Glycosyl hydrolases family 2 259 313 8.8E-10 T 22-04-2016 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 L21SP4_RS02065 8c23bbe1f083ba58c6efcfbfb085406e 850 PANTHER PTHR10066:SF12 155 703 9.6E-131 T 22-04-2016 L21SP4_RS02065 8c23bbe1f083ba58c6efcfbfb085406e 850 PANTHER PTHR10066:SF12 1 137 9.6E-131 T 22-04-2016 L21SP4_RS07065 88bc3af3b1905690ef78f60688587fe2 405 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 208 225 - T 22-04-2016 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 L21SP4_RS07065 88bc3af3b1905690ef78f60688587fe2 405 PRINTS PR00471 Acetate kinase family signature 208 229 3.6E-44 T 22-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 L21SP4_RS07065 88bc3af3b1905690ef78f60688587fe2 405 PRINTS PR00471 Acetate kinase family signature 304 317 3.6E-44 T 22-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 L21SP4_RS07065 88bc3af3b1905690ef78f60688587fe2 405 PRINTS PR00471 Acetate kinase family signature 3 14 3.6E-44 T 22-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 L21SP4_RS07065 88bc3af3b1905690ef78f60688587fe2 405 PRINTS PR00471 Acetate kinase family signature 178 191 3.6E-44 T 22-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 L21SP4_RS07065 88bc3af3b1905690ef78f60688587fe2 405 PRINTS PR00471 Acetate kinase family signature 326 342 3.6E-44 T 22-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 L21SP4_RS07065 88bc3af3b1905690ef78f60688587fe2 405 PRINTS PR00471 Acetate kinase family signature 378 390 3.6E-44 T 22-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 L21SP4_RS07065 88bc3af3b1905690ef78f60688587fe2 405 Gene3D G3DSA:3.30.420.40 1 209 5.6E-14 T 22-04-2016 L21SP4_RS07065 88bc3af3b1905690ef78f60688587fe2 405 SUPERFAMILY SSF53067 1 200 2.85E-65 T 22-04-2016 L21SP4_RS07065 88bc3af3b1905690ef78f60688587fe2 405 PIRSF PIRSF000722 1 401 1.5E-148 T 22-04-2016 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 L21SP4_RS07065 88bc3af3b1905690ef78f60688587fe2 405 Hamap MF_00020 Acetate kinase [ackA]. 1 400 176.255 T 22-04-2016 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 L21SP4_RS07065 88bc3af3b1905690ef78f60688587fe2 405 SUPERFAMILY SSF53067 162 397 6.88E-86 T 22-04-2016 L21SP4_RS07065 88bc3af3b1905690ef78f60688587fe2 405 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 3 14 - T 22-04-2016 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 L21SP4_RS07065 88bc3af3b1905690ef78f60688587fe2 405 TIGRFAM TIGR00016 ackA: acetate kinase 1 397 3.8E-150 T 22-04-2016 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 L21SP4_RS07065 88bc3af3b1905690ef78f60688587fe2 405 PANTHER PTHR21060 1 405 9.2E-203 T 22-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 L21SP4_RS07065 88bc3af3b1905690ef78f60688587fe2 405 PANTHER PTHR21060:SF11 1 405 9.2E-203 T 22-04-2016 L21SP4_RS07065 88bc3af3b1905690ef78f60688587fe2 405 Pfam PF00871 Acetokinase family 2 391 2.2E-145 T 22-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 L21SP4_RS07065 88bc3af3b1905690ef78f60688587fe2 405 Gene3D G3DSA:3.30.420.40 210 396 4.5E-78 T 22-04-2016 L21SP4_RS05930 7a42baf09463d00dde079e07ef61e9e3 80 SUPERFAMILY SSF143120 1 79 3.53E-16 T 22-04-2016 L21SP4_RS05930 7a42baf09463d00dde079e07ef61e9e3 80 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 69 1.0E-15 T 22-04-2016 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM L21SP4_RS07745 ff1a967da48c61fa2c2d71a4c6568642 185 SUPERFAMILY SSF53335 8 155 1.16E-39 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS07745 ff1a967da48c61fa2c2d71a4c6568642 185 Gene3D G3DSA:3.40.50.150 8 154 5.7E-26 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS07745 ff1a967da48c61fa2c2d71a4c6568642 185 PANTHER PTHR13600 6 154 3.1E-51 T 22-04-2016 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- L21SP4_RS07745 ff1a967da48c61fa2c2d71a4c6568642 185 Pfam PF04072 Leucine carboxyl methyltransferase 17 154 2.0E-11 T 22-04-2016 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- L21SP4_RS07745 ff1a967da48c61fa2c2d71a4c6568642 185 PANTHER PTHR13600:SF19 6 154 3.1E-51 T 22-04-2016 L21SP4_RS11315 d79b45de77f4b2d80e740099bf03df40 374 Gene3D G3DSA:3.40.50.300 7 126 7.9E-12 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS11315 d79b45de77f4b2d80e740099bf03df40 374 Pfam PF13173 AAA domain 17 137 1.4E-22 T 22-04-2016 L21SP4_RS11315 d79b45de77f4b2d80e740099bf03df40 374 SUPERFAMILY SSF52540 6 139 6.6E-19 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS11315 d79b45de77f4b2d80e740099bf03df40 374 Pfam PF13635 Domain of unknown function (DUF4143) 184 339 2.1E-20 T 22-04-2016 IPR025420 Domain of unknown function DUF4143 L21SP4_RS11315 d79b45de77f4b2d80e740099bf03df40 374 PANTHER PTHR33295 1 340 2.6E-51 T 22-04-2016 L21SP4_RS01640 03449675fb3936930be3aabae882f867 310 SMART SM00342 212 295 1.6E-28 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP4_RS01640 03449675fb3936930be3aabae882f867 310 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 249 291 - T 22-04-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 L21SP4_RS01640 03449675fb3936930be3aabae882f867 310 Gene3D G3DSA:1.10.10.60 196 248 1.5E-13 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS01640 03449675fb3936930be3aabae882f867 310 Pfam PF12833 Helix-turn-helix domain 218 296 5.1E-24 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP4_RS01640 03449675fb3936930be3aabae882f867 310 SUPERFAMILY SSF46689 248 297 1.03E-12 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS01640 03449675fb3936930be3aabae882f867 310 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 264 279 2.4E-5 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 L21SP4_RS01640 03449675fb3936930be3aabae882f867 310 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 279 295 2.4E-5 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 L21SP4_RS01640 03449675fb3936930be3aabae882f867 310 Gene3D G3DSA:2.60.120.280 30 184 2.6E-12 T 22-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 L21SP4_RS01640 03449675fb3936930be3aabae882f867 310 Gene3D G3DSA:1.10.10.60 249 297 4.1E-18 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS01640 03449675fb3936930be3aabae882f867 310 SUPERFAMILY SSF51215 29 181 7.72E-12 T 22-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 L21SP4_RS01640 03449675fb3936930be3aabae882f867 310 SUPERFAMILY SSF46689 197 247 3.32E-8 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS01640 03449675fb3936930be3aabae882f867 310 PANTHER PTHR11019 15 147 6.6E-33 T 22-04-2016 L21SP4_RS01640 03449675fb3936930be3aabae882f867 310 PANTHER PTHR11019 165 303 6.6E-33 T 22-04-2016 L21SP4_RS01640 03449675fb3936930be3aabae882f867 310 Pfam PF02311 AraC-like ligand binding domain 36 172 1.1E-5 T 22-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 L21SP4_RS11300 da13fabb850e0f0cf66adca5cb8f4a27 277 Gene3D G3DSA:3.40.50.300 2 269 6.1E-57 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS11300 da13fabb850e0f0cf66adca5cb8f4a27 277 PANTHER PTHR10605:SF40 2 180 5.0E-24 T 22-04-2016 L21SP4_RS11300 da13fabb850e0f0cf66adca5cb8f4a27 277 Pfam PF00685 Sulfotransferase domain 3 181 8.9E-17 T 22-04-2016 IPR000863 Sulfotransferase domain GO:0008146 L21SP4_RS11300 da13fabb850e0f0cf66adca5cb8f4a27 277 PANTHER PTHR10605 2 180 5.0E-24 T 22-04-2016 L21SP4_RS11300 da13fabb850e0f0cf66adca5cb8f4a27 277 SUPERFAMILY SSF52540 2 194 4.79E-62 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS11300 da13fabb850e0f0cf66adca5cb8f4a27 277 SUPERFAMILY SSF52540 230 267 4.79E-62 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS11970 0900c9c72d66a6d620d8574d8f21564b 330 SMART SM00382 30 217 6.9E-12 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS11970 0900c9c72d66a6d620d8574d8f21564b 330 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 L21SP4_RS11970 0900c9c72d66a6d620d8574d8f21564b 330 PANTHER PTHR24220:SF350 3 259 4.5E-124 T 22-04-2016 L21SP4_RS11970 0900c9c72d66a6d620d8574d8f21564b 330 Pfam PF00005 ABC transporter 21 167 6.3E-31 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 L21SP4_RS11970 0900c9c72d66a6d620d8574d8f21564b 330 Gene3D G3DSA:3.40.50.300 1 240 1.3E-74 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS11970 0900c9c72d66a6d620d8574d8f21564b 330 SUPERFAMILY SSF52540 1 243 9.21E-74 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS11970 0900c9c72d66a6d620d8574d8f21564b 330 PANTHER PTHR24220 3 259 4.5E-124 T 22-04-2016 L21SP4_RS11740 fad72eff11cca477cc9c0c6979f75bf2 359 Pfam PF13377 Periplasmic binding protein-like domain 191 354 2.8E-22 T 22-04-2016 L21SP4_RS11740 fad72eff11cca477cc9c0c6979f75bf2 359 Pfam PF00392 Bacterial regulatory proteins, gntR family 2 62 3.1E-11 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 L21SP4_RS11740 fad72eff11cca477cc9c0c6979f75bf2 359 SUPERFAMILY SSF46785 2 66 4.96E-13 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS11740 fad72eff11cca477cc9c0c6979f75bf2 359 Gene3D G3DSA:3.40.50.2300 135 189 2.0E-4 T 22-04-2016 L21SP4_RS11740 fad72eff11cca477cc9c0c6979f75bf2 359 SMART SM00345 5 62 1.5E-7 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 L21SP4_RS11740 fad72eff11cca477cc9c0c6979f75bf2 359 Gene3D G3DSA:3.40.50.2300 190 354 1.5E-34 T 22-04-2016 L21SP4_RS11740 fad72eff11cca477cc9c0c6979f75bf2 359 Gene3D G3DSA:1.10.10.10 2 68 1.0E-15 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS11740 fad72eff11cca477cc9c0c6979f75bf2 359 PANTHER PTHR30146 120 359 1.5E-28 T 22-04-2016 L21SP4_RS11740 fad72eff11cca477cc9c0c6979f75bf2 359 SUPERFAMILY SSF53822 121 355 5.3E-32 T 22-04-2016 IPR028082 Periplasmic binding protein-like I L21SP4_RS08300 70fdfaa763acad4ff2aacb4760029889 251 Pfam PF00557 Metallopeptidase family M24 12 217 3.0E-49 T 22-04-2016 IPR000994 Peptidase M24, structural domain L21SP4_RS08300 70fdfaa763acad4ff2aacb4760029889 251 PANTHER PTHR10804:SF41 1 246 2.9E-115 T 22-04-2016 L21SP4_RS08300 70fdfaa763acad4ff2aacb4760029889 251 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 165 183 - T 22-04-2016 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 L21SP4_RS08300 70fdfaa763acad4ff2aacb4760029889 251 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 2 246 4.7E-89 T 22-04-2016 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 L21SP4_RS08300 70fdfaa763acad4ff2aacb4760029889 251 SUPERFAMILY SSF55920 1 249 6.02E-79 T 22-04-2016 IPR000994 Peptidase M24, structural domain L21SP4_RS08300 70fdfaa763acad4ff2aacb4760029889 251 Hamap MF_01974 Methionine aminopeptidase [map]. 2 248 38.092 T 22-04-2016 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 L21SP4_RS08300 70fdfaa763acad4ff2aacb4760029889 251 PRINTS PR00599 Methionine aminopeptidase-1 signature 159 171 8.4E-23 T 22-04-2016 IPR001714 Peptidase M24, methionine aminopeptidase L21SP4_RS08300 70fdfaa763acad4ff2aacb4760029889 251 PRINTS PR00599 Methionine aminopeptidase-1 signature 67 80 8.4E-23 T 22-04-2016 IPR001714 Peptidase M24, methionine aminopeptidase L21SP4_RS08300 70fdfaa763acad4ff2aacb4760029889 251 PRINTS PR00599 Methionine aminopeptidase-1 signature 89 105 8.4E-23 T 22-04-2016 IPR001714 Peptidase M24, methionine aminopeptidase L21SP4_RS08300 70fdfaa763acad4ff2aacb4760029889 251 PRINTS PR00599 Methionine aminopeptidase-1 signature 190 202 8.4E-23 T 22-04-2016 IPR001714 Peptidase M24, methionine aminopeptidase L21SP4_RS08300 70fdfaa763acad4ff2aacb4760029889 251 Gene3D G3DSA:3.90.230.10 4 249 1.7E-81 T 22-04-2016 IPR000994 Peptidase M24, structural domain L21SP4_RS08300 70fdfaa763acad4ff2aacb4760029889 251 PANTHER PTHR10804 1 246 2.9E-115 T 22-04-2016 L21SP4_RS02380 78ae2ed2bf82a2a058b5f659e9f3af84 122 PANTHER PTHR30093 1 64 7.0E-20 T 22-04-2016 L21SP4_RS02380 78ae2ed2bf82a2a058b5f659e9f3af84 122 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 8 28 - T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site L21SP4_RS02380 78ae2ed2bf82a2a058b5f659e9f3af84 122 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 8 30 3.2E-8 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site L21SP4_RS02380 78ae2ed2bf82a2a058b5f659e9f3af84 122 PRINTS PR00813 Bacterial general secretion pathway protein G signature 45 63 1.1E-10 T 22-04-2016 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 L21SP4_RS02380 78ae2ed2bf82a2a058b5f659e9f3af84 122 PRINTS PR00813 Bacterial general secretion pathway protein G signature 9 34 1.1E-10 T 22-04-2016 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 L21SP4_RS02380 78ae2ed2bf82a2a058b5f659e9f3af84 122 Gene3D G3DSA:3.30.700.10 10 96 6.6E-14 T 22-04-2016 L21SP4_RS02380 78ae2ed2bf82a2a058b5f659e9f3af84 122 Pfam PF13633 Prokaryotic N-terminal methylation site 8 32 4.0E-8 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site L21SP4_RS02380 78ae2ed2bf82a2a058b5f659e9f3af84 122 SUPERFAMILY SSF54523 10 94 4.08E-18 T 22-04-2016 L21SP4_RS10635 6536199483b8f342e8d06e5cfcfd1906 104 Hamap MF_01663 L-rhamnose mutarotase [rhaM]. 1 104 31.459 T 22-04-2016 IPR013448 L-rhamnose mutarotase GO:0005737|GO:0016857|GO:0019299 UniPathway: UPA00125 L21SP4_RS10635 6536199483b8f342e8d06e5cfcfd1906 104 PANTHER PTHR34389:SF2 1 104 2.0E-39 T 22-04-2016 L21SP4_RS10635 6536199483b8f342e8d06e5cfcfd1906 104 TIGRFAM TIGR02625 YiiL_rotase: L-rhamnose mutarotase 3 104 3.7E-34 T 22-04-2016 IPR013448 L-rhamnose mutarotase GO:0005737|GO:0016857|GO:0019299 UniPathway: UPA00125 L21SP4_RS10635 6536199483b8f342e8d06e5cfcfd1906 104 PANTHER PTHR34389 1 104 2.0E-39 T 22-04-2016 L21SP4_RS10635 6536199483b8f342e8d06e5cfcfd1906 104 Pfam PF05336 Domain of unknown function (DUF718) 3 103 9.7E-31 T 22-04-2016 IPR008000 Rhamnose/fucose mutarotase GO:0005737|GO:0016857 UniPathway: UPA00125 L21SP4_RS10635 6536199483b8f342e8d06e5cfcfd1906 104 SUPERFAMILY SSF54909 1 104 3.62E-38 T 22-04-2016 IPR011008 Dimeric alpha-beta barrel L21SP4_RS12170 8a6de20bfb816c9194c7950e6cba5d21 598 SUPERFAMILY SSF54211 196 329 1.02E-31 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold L21SP4_RS12170 8a6de20bfb816c9194c7950e6cba5d21 598 SMART SM00853 410 553 7.8E-36 T 22-04-2016 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 L21SP4_RS12170 8a6de20bfb816c9194c7950e6cba5d21 598 Gene3D G3DSA:3.30.565.10 6 206 2.5E-68 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS12170 8a6de20bfb816c9194c7950e6cba5d21 598 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 28 128 2.4E-12 T 22-04-2016 L21SP4_RS12170 8a6de20bfb816c9194c7950e6cba5d21 598 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 5 593 24.948 T 22-04-2016 IPR020667 DNA mismatch repair protein, MutL GO:0006298 L21SP4_RS12170 8a6de20bfb816c9194c7950e6cba5d21 598 SUPERFAMILY SSF118116 408 595 1.31E-46 T 22-04-2016 L21SP4_RS12170 8a6de20bfb816c9194c7950e6cba5d21 598 PANTHER PTHR10073 7 596 9.2E-143 T 22-04-2016 L21SP4_RS12170 8a6de20bfb816c9194c7950e6cba5d21 598 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 213 329 7.6E-31 T 22-04-2016 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 L21SP4_RS12170 8a6de20bfb816c9194c7950e6cba5d21 598 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 5 310 6.4E-88 T 22-04-2016 IPR002099 DNA mismatch repair protein family GO:0005524|GO:0006298|GO:0030983 L21SP4_RS12170 8a6de20bfb816c9194c7950e6cba5d21 598 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 97 103 - T 22-04-2016 IPR014762 DNA mismatch repair, conserved site L21SP4_RS12170 8a6de20bfb816c9194c7950e6cba5d21 598 Pfam PF08676 MutL C terminal dimerisation domain 410 553 3.0E-33 T 22-04-2016 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 L21SP4_RS12170 8a6de20bfb816c9194c7950e6cba5d21 598 SMART SM01340 212 330 9.2E-48 T 22-04-2016 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 L21SP4_RS12170 8a6de20bfb816c9194c7950e6cba5d21 598 SUPERFAMILY SSF55874 4 217 7.99E-52 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS12170 8a6de20bfb816c9194c7950e6cba5d21 598 Gene3D G3DSA:3.30.230.10 207 328 3.3E-31 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup L21SP4_RS01720 f0acab32fc9ad8ad28c6758700cdbfa9 318 PANTHER PTHR30606 1 302 5.8E-55 T 22-04-2016 L21SP4_RS01720 f0acab32fc9ad8ad28c6758700cdbfa9 318 PANTHER PTHR30606:SF2 1 302 5.8E-55 T 22-04-2016 L21SP4_RS01720 f0acab32fc9ad8ad28c6758700cdbfa9 318 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 25 302 3.2E-35 T 22-04-2016 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 L21SP4_RS03680 3d260cdb64b75d66d5fe3be9f9f96f19 755 SUPERFAMILY SSF52402 484 614 4.27E-12 T 22-04-2016 L21SP4_RS03680 3d260cdb64b75d66d5fe3be9f9f96f19 755 Pfam PF00324 Amino acid permease 20 459 1.6E-48 T 22-04-2016 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 L21SP4_RS03680 3d260cdb64b75d66d5fe3be9f9f96f19 755 Gene3D G3DSA:3.40.50.620 608 742 6.3E-11 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP4_RS03680 3d260cdb64b75d66d5fe3be9f9f96f19 755 PANTHER PTHR11785 10 481 4.5E-96 T 22-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 L21SP4_RS03680 3d260cdb64b75d66d5fe3be9f9f96f19 755 SUPERFAMILY SSF52402 620 742 1.67E-14 T 22-04-2016 L21SP4_RS03680 3d260cdb64b75d66d5fe3be9f9f96f19 755 Gene3D G3DSA:3.40.50.620 485 607 3.7E-10 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP4_RS03680 3d260cdb64b75d66d5fe3be9f9f96f19 755 Pfam PF00582 Universal stress protein family 621 742 2.8E-5 T 22-04-2016 IPR006016 UspA GO:0006950 L21SP4_RS03680 3d260cdb64b75d66d5fe3be9f9f96f19 755 Pfam PF00582 Universal stress protein family 501 614 1.0E-8 T 22-04-2016 IPR006016 UspA GO:0006950 L21SP4_RS08445 0ba34063b258d621f49b2d931c1bca54 183 Pfam PF00466 Ribosomal protein L10 9 105 2.0E-15 T 22-04-2016 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 L21SP4_RS08445 0ba34063b258d621f49b2d931c1bca54 183 SUPERFAMILY SSF160369 8 176 1.83E-40 T 22-04-2016 L21SP4_RS08445 0ba34063b258d621f49b2d931c1bca54 183 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 7 176 20.629 T 22-04-2016 IPR022973 Ribosomal protein L10 L21SP4_RS08445 0ba34063b258d621f49b2d931c1bca54 183 PANTHER PTHR11560 1 183 3.3E-38 T 22-04-2016 L21SP4_RS08945 bcbc44a4f9a4afa7d38ff0cc8366ab92 408 PANTHER PTHR30160:SF1 31 408 1.9E-22 T 22-04-2016 L21SP4_RS08945 bcbc44a4f9a4afa7d38ff0cc8366ab92 408 Gene3D G3DSA:3.40.50.2000 230 399 2.2E-34 T 22-04-2016 L21SP4_RS08945 bcbc44a4f9a4afa7d38ff0cc8366ab92 408 SUPERFAMILY SSF53756 36 399 3.98E-50 T 22-04-2016 L21SP4_RS08945 bcbc44a4f9a4afa7d38ff0cc8366ab92 408 Gene3D G3DSA:3.40.50.2000 36 184 2.5E-12 T 22-04-2016 L21SP4_RS08945 bcbc44a4f9a4afa7d38ff0cc8366ab92 408 PANTHER PTHR30160 31 408 1.9E-22 T 22-04-2016 L21SP4_RS08945 bcbc44a4f9a4afa7d38ff0cc8366ab92 408 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 117 368 2.0E-14 T 22-04-2016 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 L21SP4_RS01925 0fff1fe2352c69005483821a7c35eed1 237 PANTHER PTHR21139 26 178 1.2E-13 T 22-04-2016 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 L21SP4_RS01925 0fff1fe2352c69005483821a7c35eed1 237 Pfam PF00121 Triosephosphate isomerase 32 131 3.2E-6 T 22-04-2016 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 L21SP4_RS01925 0fff1fe2352c69005483821a7c35eed1 237 SUPERFAMILY SSF51351 7 220 3.67E-37 T 22-04-2016 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 L21SP4_RS01925 0fff1fe2352c69005483821a7c35eed1 237 Gene3D G3DSA:3.20.20.70 35 224 2.5E-36 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP4_RS08745 96f7cfe0c2ca96fa6f9e0d7c36ab5c54 648 Pfam PF02779 Transketolase, pyrimidine binding domain 335 506 4.0E-40 T 22-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain L21SP4_RS08745 96f7cfe0c2ca96fa6f9e0d7c36ab5c54 648 PANTHER PTHR11624 323 648 0.0 T 22-04-2016 IPR033247 Transketolase family L21SP4_RS08745 96f7cfe0c2ca96fa6f9e0d7c36ab5c54 648 PANTHER PTHR11624 1 296 0.0 T 22-04-2016 IPR033247 Transketolase family L21SP4_RS08745 96f7cfe0c2ca96fa6f9e0d7c36ab5c54 648 Gene3D G3DSA:3.40.50.920 521 647 1.2E-44 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 L21SP4_RS08745 96f7cfe0c2ca96fa6f9e0d7c36ab5c54 648 TIGRFAM TIGR00232 tktlase_bact: transketolase 1 645 3.8E-262 T 22-04-2016 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 L21SP4_RS08745 96f7cfe0c2ca96fa6f9e0d7c36ab5c54 648 SUPERFAMILY SSF52518 326 509 9.99E-66 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold L21SP4_RS08745 96f7cfe0c2ca96fa6f9e0d7c36ab5c54 648 ProSitePatterns PS00802 Transketolase signature 2. 449 465 - T 22-04-2016 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 L21SP4_RS08745 96f7cfe0c2ca96fa6f9e0d7c36ab5c54 648 PANTHER PTHR11624:SF1 323 648 0.0 T 22-04-2016 L21SP4_RS08745 96f7cfe0c2ca96fa6f9e0d7c36ab5c54 648 PANTHER PTHR11624:SF1 1 296 0.0 T 22-04-2016 L21SP4_RS08745 96f7cfe0c2ca96fa6f9e0d7c36ab5c54 648 Gene3D G3DSA:3.40.50.970 315 512 6.9E-69 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold L21SP4_RS08745 96f7cfe0c2ca96fa6f9e0d7c36ab5c54 648 SUPERFAMILY SSF52922 518 648 1.27E-38 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 L21SP4_RS08745 96f7cfe0c2ca96fa6f9e0d7c36ab5c54 648 SMART SM00861 336 507 6.0E-65 T 22-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain L21SP4_RS08745 96f7cfe0c2ca96fa6f9e0d7c36ab5c54 648 Gene3D G3DSA:3.40.50.970 1 304 4.2E-121 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold L21SP4_RS08745 96f7cfe0c2ca96fa6f9e0d7c36ab5c54 648 SUPERFAMILY SSF52518 2 310 5.63E-110 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold L21SP4_RS08745 96f7cfe0c2ca96fa6f9e0d7c36ab5c54 648 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 1 320 7.8E-138 T 22-04-2016 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 L21SP4_RS08745 96f7cfe0c2ca96fa6f9e0d7c36ab5c54 648 Pfam PF02780 Transketolase, C-terminal domain 534 639 1.7E-10 T 22-04-2016 IPR033248 Transketolase, C-terminal domain L21SP4_RS06190 f71a173b89efef30b723e253fbf1135a 459 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 1 444 28.84 T 22-04-2016 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 L21SP4_RS06190 f71a173b89efef30b723e253fbf1135a 459 PANTHER PTHR30008 2 456 2.8E-158 T 22-04-2016 L21SP4_RS06190 f71a173b89efef30b723e253fbf1135a 459 Pfam PF13742 OB-fold nucleic acid binding domain 5 96 6.3E-30 T 22-04-2016 IPR025824 OB-fold nucleic acid binding domain GO:0003676 L21SP4_RS06190 f71a173b89efef30b723e253fbf1135a 459 PANTHER PTHR30008:SF0 2 456 2.8E-158 T 22-04-2016 L21SP4_RS06190 f71a173b89efef30b723e253fbf1135a 459 Pfam PF02601 Exonuclease VII, large subunit 120 441 1.2E-93 T 22-04-2016 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 L21SP4_RS06190 f71a173b89efef30b723e253fbf1135a 459 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 6 443 1.9E-142 T 22-04-2016 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 L21SP4_RS05760 ca332af7d2fd97e19446664937355750 205 Pfam PF03938 Outer membrane protein (OmpH-like) 14 188 1.8E-24 T 22-04-2016 IPR005632 Chaperone protein Skp GO:0051082 L21SP4_RS05760 ca332af7d2fd97e19446664937355750 205 SUPERFAMILY SSF111384 26 190 1.44E-15 T 22-04-2016 IPR024930 Skp domain L21SP4_RS05760 ca332af7d2fd97e19446664937355750 205 SMART SM00935 15 190 1.0E-16 T 22-04-2016 IPR005632 Chaperone protein Skp GO:0051082 L21SP4_RS05760 ca332af7d2fd97e19446664937355750 205 PANTHER PTHR35089 8 196 2.9E-19 T 22-04-2016 L21SP4_RS05760 ca332af7d2fd97e19446664937355750 205 Gene3D G3DSA:3.30.910.20 109 190 3.1E-14 T 22-04-2016 L21SP4_RS05760 ca332af7d2fd97e19446664937355750 205 Gene3D G3DSA:3.30.910.20 17 63 3.1E-14 T 22-04-2016 L21SP4_RS05760 ca332af7d2fd97e19446664937355750 205 Pfam PF15047 Protein of unknown function (DUF4533) 35 117 9.9E-7 T 22-04-2016 IPR027895 Protein of unknown function DUF4533 L21SP4_RS05995 3f78022cabbc96e510fb682f2dbbedec 607 Gene3D G3DSA:3.40.50.1820 90 332 1.5E-26 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold L21SP4_RS05995 3f78022cabbc96e510fb682f2dbbedec 607 Pfam PF10142 PhoPQ-activated pathogenicity-related protein 275 337 6.6E-5 T 22-04-2016 IPR009199 PhoPQ-activated pathogenicity-related protein, PqaA type L21SP4_RS05995 3f78022cabbc96e510fb682f2dbbedec 607 SUPERFAMILY SSF53474 79 333 6.46E-24 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold L21SP4_RS05995 3f78022cabbc96e510fb682f2dbbedec 607 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 192 234 3.5E-5 T 22-04-2016 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 L21SP4_RS10865 9390634a2d2a3f615de2d190ed9ead12 111 Gene3D G3DSA:2.20.28.10 1 38 1.7E-19 T 22-04-2016 IPR004039 Rubredoxin-type fold L21SP4_RS10865 9390634a2d2a3f615de2d190ed9ead12 111 SUPERFAMILY SSF57802 1 40 3.87E-13 T 22-04-2016 L21SP4_RS09070 862b95a79e1d425f37574c7f7ed2f081 353 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 206 345 2.3E-37 T 22-04-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily L21SP4_RS09070 862b95a79e1d425f37574c7f7ed2f081 353 SUPERFAMILY SSF55821 1 193 7.32E-45 T 22-04-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain L21SP4_RS09070 862b95a79e1d425f37574c7f7ed2f081 353 Pfam PF01300 Telomere recombination 23 187 4.9E-34 T 22-04-2016 IPR006070 YrdC-like domain GO:0003725 L21SP4_RS09070 862b95a79e1d425f37574c7f7ed2f081 353 Gene3D G3DSA:3.90.870.10 6 194 6.9E-48 T 22-04-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain L21SP4_RS09070 862b95a79e1d425f37574c7f7ed2f081 353 SMART SM00226 204 348 9.4E-41 T 22-04-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily L21SP4_RS09070 862b95a79e1d425f37574c7f7ed2f081 353 SUPERFAMILY SSF52788 206 347 4.19E-38 T 22-04-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily L21SP4_RS09070 862b95a79e1d425f37574c7f7ed2f081 353 Gene3D G3DSA:3.40.50.270 206 349 2.1E-45 T 22-04-2016 L21SP4_RS09070 862b95a79e1d425f37574c7f7ed2f081 353 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 279 294 6.82E-9 T 22-04-2016 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 L21SP4_RS09070 862b95a79e1d425f37574c7f7ed2f081 353 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 301 314 6.82E-9 T 22-04-2016 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 L21SP4_RS09070 862b95a79e1d425f37574c7f7ed2f081 353 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 320 335 6.82E-9 T 22-04-2016 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 L21SP4_RS09070 862b95a79e1d425f37574c7f7ed2f081 353 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 206 223 6.82E-9 T 22-04-2016 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 L21SP4_RS09070 862b95a79e1d425f37574c7f7ed2f081 353 PANTHER PTHR17490 1 196 1.5E-46 T 22-04-2016 L21SP4_RS10735 81d1acb30c04c74a7961cd7c428b9b3f 99 Pfam PF14236 Domain of unknown function (DUF4338) 18 87 2.0E-9 T 22-04-2016 IPR025639 Domain of unknown function DUF4338 L21SP4_RS08030 a3b6cf8e0a11abac08353b7c22e5d45e 331 SUPERFAMILY SSF51395 19 328 4.39E-64 T 22-04-2016 L21SP4_RS08030 a3b6cf8e0a11abac08353b7c22e5d45e 331 PIRSF PIRSF006621 9 331 9.8E-73 T 22-04-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 L21SP4_RS08030 a3b6cf8e0a11abac08353b7c22e5d45e 331 Pfam PF01207 Dihydrouridine synthase (Dus) 23 327 2.4E-62 T 22-04-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 L21SP4_RS08030 a3b6cf8e0a11abac08353b7c22e5d45e 331 Gene3D G3DSA:3.20.20.70 17 246 1.2E-66 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP4_RS08030 a3b6cf8e0a11abac08353b7c22e5d45e 331 PANTHER PTHR11082:SF25 10 328 2.8E-84 T 22-04-2016 L21SP4_RS08030 a3b6cf8e0a11abac08353b7c22e5d45e 331 PANTHER PTHR11082 10 328 2.8E-84 T 22-04-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 L21SP4_RS08030 a3b6cf8e0a11abac08353b7c22e5d45e 331 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 104 122 - T 22-04-2016 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 L21SP4_RS08030 a3b6cf8e0a11abac08353b7c22e5d45e 331 Gene3D G3DSA:1.10.1200.80 257 327 3.5E-6 T 22-04-2016 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 L21SP4_RS04275 6cad4c8caa9be2df1e44a8a148d14957 351 SMART SM01133 69 327 1.1E-37 T 22-04-2016 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 L21SP4_RS04275 6cad4c8caa9be2df1e44a8a148d14957 351 Pfam PF01791 DeoC/LacD family aldolase 70 327 1.2E-63 T 22-04-2016 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 L21SP4_RS04275 6cad4c8caa9be2df1e44a8a148d14957 351 Gene3D G3DSA:3.20.20.70 56 344 5.1E-98 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP4_RS04275 6cad4c8caa9be2df1e44a8a148d14957 351 SUPERFAMILY SSF51569 272 343 7.81E-65 T 22-04-2016 L21SP4_RS04275 6cad4c8caa9be2df1e44a8a148d14957 351 SUPERFAMILY SSF51569 58 243 7.81E-65 T 22-04-2016 L21SP4_RS06370 b0664165f1a3d6c8f7eee85438f82f89 1012 Gene3D G3DSA:1.10.1060.10 525 631 3.8E-22 T 22-04-2016 L21SP4_RS06370 b0664165f1a3d6c8f7eee85438f82f89 1012 Gene3D G3DSA:1.10.1060.10 964 1004 1.3E-7 T 22-04-2016 L21SP4_RS06370 b0664165f1a3d6c8f7eee85438f82f89 1012 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 448 459 - T 22-04-2016 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 L21SP4_RS06370 b0664165f1a3d6c8f7eee85438f82f89 1012 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 436 520 3.2E-34 T 22-04-2016 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 L21SP4_RS06370 b0664165f1a3d6c8f7eee85438f82f89 1012 SUPERFAMILY SSF52833 2 91 1.23E-23 T 22-04-2016 IPR012336 Thioredoxin-like fold L21SP4_RS06370 b0664165f1a3d6c8f7eee85438f82f89 1012 SUPERFAMILY SSF142984 347 430 7.19E-25 T 22-04-2016 L21SP4_RS06370 b0664165f1a3d6c8f7eee85438f82f89 1012 PRINTS PR00419 Adrenodoxin reductase family signature 630 652 2.3E-17 T 22-04-2016 L21SP4_RS06370 b0664165f1a3d6c8f7eee85438f82f89 1012 PRINTS PR00419 Adrenodoxin reductase family signature 653 666 2.3E-17 T 22-04-2016 L21SP4_RS06370 b0664165f1a3d6c8f7eee85438f82f89 1012 PRINTS PR00419 Adrenodoxin reductase family signature 762 776 2.3E-17 T 22-04-2016 L21SP4_RS06370 b0664165f1a3d6c8f7eee85438f82f89 1012 PRINTS PR00419 Adrenodoxin reductase family signature 695 705 2.3E-17 T 22-04-2016 L21SP4_RS06370 b0664165f1a3d6c8f7eee85438f82f89 1012 PANTHER PTHR11780 1 549 0.0 T 22-04-2016 L21SP4_RS06370 b0664165f1a3d6c8f7eee85438f82f89 1012 PANTHER PTHR11780:SF0 1 549 0.0 T 22-04-2016 L21SP4_RS06370 b0664165f1a3d6c8f7eee85438f82f89 1012 Gene3D G3DSA:3.40.50.720 632 718 1.7E-21 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS06370 b0664165f1a3d6c8f7eee85438f82f89 1012 Gene3D G3DSA:3.40.50.720 875 943 1.7E-21 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS06370 b0664165f1a3d6c8f7eee85438f82f89 1012 Gene3D G3DSA:3.50.50.60 719 871 2.4E-48 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP4_RS06370 b0664165f1a3d6c8f7eee85438f82f89 1012 SUPERFAMILY SSF46548 534 639 2.77E-14 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 L21SP4_RS06370 b0664165f1a3d6c8f7eee85438f82f89 1012 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 154 325 5.0E-47 T 22-04-2016 IPR011538 NADH-ubiquinone oxidoreductase 51 kDa subunit, FMN-binding domain L21SP4_RS06370 b0664165f1a3d6c8f7eee85438f82f89 1012 SUPERFAMILY SSF46548 949 1004 2.09E-5 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 L21SP4_RS06370 b0664165f1a3d6c8f7eee85438f82f89 1012 SUPERFAMILY SSF142019 106 346 9.81E-90 T 22-04-2016 L21SP4_RS06370 b0664165f1a3d6c8f7eee85438f82f89 1012 Gene3D G3DSA:3.40.30.10 2 95 7.6E-29 T 22-04-2016 IPR012336 Thioredoxin-like fold L21SP4_RS06370 b0664165f1a3d6c8f7eee85438f82f89 1012 SUPERFAMILY SSF51971 629 871 5.12E-63 T 22-04-2016 L21SP4_RS06370 b0664165f1a3d6c8f7eee85438f82f89 1012 SMART SM00928 435 480 2.2E-24 T 22-04-2016 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 L21SP4_RS06370 b0664165f1a3d6c8f7eee85438f82f89 1012 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 525 612 1.9E-16 T 22-04-2016 IPR028261 Dihydroprymidine dehydrogenase domain II L21SP4_RS06370 b0664165f1a3d6c8f7eee85438f82f89 1012 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 630 926 1.2E-33 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP4_RS06370 b0664165f1a3d6c8f7eee85438f82f89 1012 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 2 76 1.0E-6 T 22-04-2016 L21SP4_RS06370 b0664165f1a3d6c8f7eee85438f82f89 1012 Pfam PF10531 SLBB domain 349 397 4.2E-7 T 22-04-2016 IPR019554 Soluble ligand binding domain L21SP4_RS06370 b0664165f1a3d6c8f7eee85438f82f89 1012 SUPERFAMILY SSF140490 432 532 4.18E-38 T 22-04-2016 L21SP4_RS01240 6717ead8860f754bb353465e0c53d5a6 75 Pfam PF11146 Protein of unknown function (DUF2905) 7 69 1.1E-22 T 22-04-2016 IPR021320 Protein of unknown function DUF2905 L21SP4_RS01240 6717ead8860f754bb353465e0c53d5a6 75 PANTHER PTHR36443 1 74 4.2E-20 T 22-04-2016 L21SP4_RS01240 6717ead8860f754bb353465e0c53d5a6 75 PANTHER PTHR36443:SF1 1 74 4.2E-20 T 22-04-2016 L21SP4_RS01975 ac0d38670813164db1f88dd8aa53eadd 742 SUPERFAMILY SSF52540 200 381 1.25E-44 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS01975 ac0d38670813164db1f88dd8aa53eadd 742 Pfam PF04851 Type III restriction enzyme, res subunit 204 367 1.0E-14 T 22-04-2016 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 L21SP4_RS01975 ac0d38670813164db1f88dd8aa53eadd 742 PANTHER PTHR30580 1 742 1.4E-261 T 22-04-2016 L21SP4_RS01975 ac0d38670813164db1f88dd8aa53eadd 742 Hamap MF_00983 Probable primosomal protein N' [priA]. 12 741 24.671 T 22-04-2016 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 L21SP4_RS01975 ac0d38670813164db1f88dd8aa53eadd 742 Gene3D G3DSA:1.10.10.10 135 206 4.9E-5 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS01975 ac0d38670813164db1f88dd8aa53eadd 742 SUPERFAMILY SSF52540 472 639 1.48E-23 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS01975 ac0d38670813164db1f88dd8aa53eadd 742 SMART SM00487 201 400 3.3E-28 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain L21SP4_RS01975 ac0d38670813164db1f88dd8aa53eadd 742 TIGRFAM TIGR00595 priA: primosomal protein N' 229 737 1.1E-193 T 22-04-2016 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 L21SP4_RS01975 ac0d38670813164db1f88dd8aa53eadd 742 Gene3D G3DSA:3.40.50.300 207 390 4.0E-43 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS01975 ac0d38670813164db1f88dd8aa53eadd 742 Pfam PF00271 Helicase conserved C-terminal domain 516 602 3.4E-9 T 22-04-2016 IPR001650 Helicase, C-terminal L21SP4_RS01975 ac0d38670813164db1f88dd8aa53eadd 742 Gene3D G3DSA:3.40.50.300 417 440 1.4E-30 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS01975 ac0d38670813164db1f88dd8aa53eadd 742 Gene3D G3DSA:3.40.50.300 506 647 1.4E-30 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS01975 ac0d38670813164db1f88dd8aa53eadd 742 SMART SM00490 506 603 8.8E-12 T 22-04-2016 IPR001650 Helicase, C-terminal L21SP4_RS07245 e14fe33d1d34dd6e2d400f31201c2221 458 PANTHER PTHR10342 1 457 1.6E-148 T 22-04-2016 L21SP4_RS07245 e14fe33d1d34dd6e2d400f31201c2221 458 Gene3D G3DSA:3.40.720.10 21 378 9.7E-112 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS07245 e14fe33d1d34dd6e2d400f31201c2221 458 SUPERFAMILY SSF53649 22 431 3.21E-123 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS07245 e14fe33d1d34dd6e2d400f31201c2221 458 PANTHER PTHR10342:SF199 1 457 1.6E-148 T 22-04-2016 L21SP4_RS07245 e14fe33d1d34dd6e2d400f31201c2221 458 Pfam PF00884 Sulfatase 23 341 2.7E-73 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS07245 e14fe33d1d34dd6e2d400f31201c2221 458 Gene3D G3DSA:3.30.1120.10 379 437 6.3E-19 T 22-04-2016 L21SP4_RS07245 e14fe33d1d34dd6e2d400f31201c2221 458 ProSitePatterns PS00149 Sulfatases signature 2. 122 132 - T 22-04-2016 IPR024607 Sulfatase, conserved site L21SP4_RS06395 ff51c0836cefcea325dd6328e028eec6 612 Gene3D G3DSA:3.40.50.1780 310 440 2.1E-70 T 22-04-2016 L21SP4_RS06395 ff51c0836cefcea325dd6328e028eec6 612 Gene3D G3DSA:3.40.50.1780 200 251 2.1E-70 T 22-04-2016 L21SP4_RS06395 ff51c0836cefcea325dd6328e028eec6 612 Gene3D G3DSA:3.10.20.30 4 61 9.3E-10 T 22-04-2016 IPR012675 Beta-grasp domain L21SP4_RS06395 ff51c0836cefcea325dd6328e028eec6 612 SUPERFAMILY SSF53920 193 605 3.4E-114 T 22-04-2016 IPR009016 Iron hydrogenase L21SP4_RS06395 ff51c0836cefcea325dd6328e028eec6 612 SMART SM00929 86 126 5.8E-13 T 22-04-2016 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 L21SP4_RS06395 ff51c0836cefcea325dd6328e028eec6 612 Pfam PF00037 4Fe-4S binding domain 193 209 1.0E-4 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain L21SP4_RS06395 ff51c0836cefcea325dd6328e028eec6 612 PANTHER PTHR11615 495 610 3.8E-123 T 22-04-2016 L21SP4_RS06395 ff51c0836cefcea325dd6328e028eec6 612 PANTHER PTHR11615 6 475 3.8E-123 T 22-04-2016 L21SP4_RS06395 ff51c0836cefcea325dd6328e028eec6 612 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 86 122 3.4E-13 T 22-04-2016 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 L21SP4_RS06395 ff51c0836cefcea325dd6328e028eec6 612 Gene3D G3DSA:4.10.260.20 549 610 4.5E-23 T 22-04-2016 IPR003149 Iron hydrogenase, small subunit L21SP4_RS06395 ff51c0836cefcea325dd6328e028eec6 612 SUPERFAMILY SSF54292 4 77 8.59E-19 T 22-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 L21SP4_RS06395 ff51c0836cefcea325dd6328e028eec6 612 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 3 79 4.6E-19 T 22-04-2016 L21SP4_RS06395 ff51c0836cefcea325dd6328e028eec6 612 PANTHER PTHR11615:SF112 495 610 3.8E-123 T 22-04-2016 L21SP4_RS06395 ff51c0836cefcea325dd6328e028eec6 612 PANTHER PTHR11615:SF112 6 475 3.8E-123 T 22-04-2016 L21SP4_RS06395 ff51c0836cefcea325dd6328e028eec6 612 TIGRFAM TIGR02512 FeFe_hydrog_A: [FeFe] hydrogenase, group A 142 547 4.9E-139 T 22-04-2016 IPR013352 Iron hydrogenase, subset GO:0005506|GO:0008901|GO:0051536|GO:0055114 L21SP4_RS06395 ff51c0836cefcea325dd6328e028eec6 612 Gene3D G3DSA:3.30.70.20 131 199 4.7E-13 T 22-04-2016 L21SP4_RS06395 ff51c0836cefcea325dd6328e028eec6 612 SUPERFAMILY SSF54862 78 216 9.21E-33 T 22-04-2016 L21SP4_RS06395 ff51c0836cefcea325dd6328e028eec6 612 Pfam PF02906 Iron only hydrogenase large subunit, C-terminal domain 226 543 2.1E-82 T 22-04-2016 IPR004108 Iron hydrogenase, large subunit, C-terminal L21SP4_RS06395 ff51c0836cefcea325dd6328e028eec6 612 SMART SM00902 548 608 2.0E-25 T 22-04-2016 IPR003149 Iron hydrogenase, small subunit L21SP4_RS06395 ff51c0836cefcea325dd6328e028eec6 612 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 193 204 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site L21SP4_RS06395 ff51c0836cefcea325dd6328e028eec6 612 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 34 51 - T 22-04-2016 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 L21SP4_RS06395 ff51c0836cefcea325dd6328e028eec6 612 Pfam PF02256 Iron hydrogenase small subunit 552 607 1.1E-22 T 22-04-2016 IPR003149 Iron hydrogenase, small subunit L21SP4_RS00470 1bac5d93268acf15066bd313744c4d95 329 SUPERFAMILY SSF52540 14 298 2.95E-41 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS00470 1bac5d93268acf15066bd313744c4d95 329 PANTHER PTHR11603 6 325 1.8E-136 T 22-04-2016 L21SP4_RS00470 1bac5d93268acf15066bd313744c4d95 329 Gene3D G3DSA:3.40.50.300 24 192 9.9E-44 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS00470 1bac5d93268acf15066bd313744c4d95 329 PANTHER PTHR11603:SF156 6 325 1.8E-136 T 22-04-2016 L21SP4_RS00470 1bac5d93268acf15066bd313744c4d95 329 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 43 176 2.7E-63 T 22-04-2016 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 L21SP4_RS00470 1bac5d93268acf15066bd313744c4d95 329 Gene3D G3DSA:1.10.8.300 206 323 2.0E-32 T 22-04-2016 L21SP4_RS00470 1bac5d93268acf15066bd313744c4d95 329 PIRSF PIRSF002849 1 328 1.9E-120 T 22-04-2016 IPR016366 ATPase chaperone, AAA-type, MoxR, predicted L21SP4_RS08625 e0f19609cc7fb169d292d0ffafd3b49e 381 Pfam PF00953 Glycosyl transferase family 4 99 287 1.3E-34 T 22-04-2016 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 L21SP4_RS08625 e0f19609cc7fb169d292d0ffafd3b49e 381 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 24 379 21.455 T 22-04-2016 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 L21SP4_RS08625 e0f19609cc7fb169d292d0ffafd3b49e 381 PANTHER PTHR22926 2 381 3.1E-130 T 22-04-2016 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 L21SP4_RS08625 e0f19609cc7fb169d292d0ffafd3b49e 381 ProSitePatterns PS01348 MraY family signature 2. 192 203 - T 22-04-2016 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 L21SP4_RS08625 e0f19609cc7fb169d292d0ffafd3b49e 381 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 36 381 9.7E-100 T 22-04-2016 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 L21SP4_RS08625 e0f19609cc7fb169d292d0ffafd3b49e 381 PANTHER PTHR22926:SF5 2 381 3.1E-130 T 22-04-2016 L21SP4_RS08625 e0f19609cc7fb169d292d0ffafd3b49e 381 ProSitePatterns PS01347 MraY family signature 1. 68 80 - T 22-04-2016 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 L21SP4_RS08625 e0f19609cc7fb169d292d0ffafd3b49e 381 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 68 80 5.0E-6 T 22-04-2016 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 L21SP4_RS01600 843e90afaa093eabf0962048bf07972c 605 Gene3D G3DSA:3.30.1120.10 382 453 8.1E-14 T 22-04-2016 L21SP4_RS01600 843e90afaa093eabf0962048bf07972c 605 Gene3D G3DSA:3.40.720.10 11 366 1.9E-92 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS01600 843e90afaa093eabf0962048bf07972c 605 Pfam PF00884 Sulfatase 13 348 4.4E-55 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS01600 843e90afaa093eabf0962048bf07972c 605 Pfam PF16347 Domain of unknown function (DUF4976) 351 450 4.9E-18 T 22-04-2016 IPR032506 Domain of unknown function DUF4976 L21SP4_RS01600 843e90afaa093eabf0962048bf07972c 605 PANTHER PTHR10342:SF237 237 475 5.4E-126 T 22-04-2016 L21SP4_RS01600 843e90afaa093eabf0962048bf07972c 605 PANTHER PTHR10342:SF237 12 213 5.4E-126 T 22-04-2016 L21SP4_RS01600 843e90afaa093eabf0962048bf07972c 605 PANTHER PTHR10342 237 475 5.4E-126 T 22-04-2016 L21SP4_RS01600 843e90afaa093eabf0962048bf07972c 605 PANTHER PTHR10342 12 213 5.4E-126 T 22-04-2016 L21SP4_RS01600 843e90afaa093eabf0962048bf07972c 605 SUPERFAMILY SSF53649 12 451 5.82E-114 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS05990 ac34bd6f736be59135c9670304d28e46 643 PANTHER PTHR30175 161 340 1.2E-23 T 22-04-2016 L21SP4_RS05990 ac34bd6f736be59135c9670304d28e46 643 SUPERFAMILY SSF49899 483 642 1.35E-12 T 22-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP4_RS05990 ac34bd6f736be59135c9670304d28e46 643 Gene3D G3DSA:2.60.120.560 459 640 1.1E-16 T 22-04-2016 IPR013189 Glycosyl hydrolase family 32, C-terminal L21SP4_RS05990 ac34bd6f736be59135c9670304d28e46 643 SUPERFAMILY SSF75005 176 483 8.86E-50 T 22-04-2016 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP4_RS05990 ac34bd6f736be59135c9670304d28e46 643 PANTHER PTHR30175 357 604 1.2E-23 T 22-04-2016 L21SP4_RS05990 ac34bd6f736be59135c9670304d28e46 643 Gene3D G3DSA:2.115.10.20 202 398 5.7E-13 T 22-04-2016 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP4_RS05990 ac34bd6f736be59135c9670304d28e46 643 PANTHER PTHR30175:SF0 357 604 1.2E-23 T 22-04-2016 L21SP4_RS05990 ac34bd6f736be59135c9670304d28e46 643 SMART SM00640 185 605 1.9E-15 T 22-04-2016 IPR001362 Glycoside hydrolase, family 32 GO:0004553|GO:0005975 L21SP4_RS05990 ac34bd6f736be59135c9670304d28e46 643 PANTHER PTHR30175:SF0 161 340 1.2E-23 T 22-04-2016 L21SP4_RS05990 ac34bd6f736be59135c9670304d28e46 643 Pfam PF00251 Glycosyl hydrolases family 32 N-terminal domain 189 483 1.2E-33 T 22-04-2016 IPR013148 Glycosyl hydrolase family 32, N-terminal L21SP4_RS05300 8b419cf86112bb054277daf575b668d0 263 Gene3D G3DSA:3.40.1280.10 109 258 2.5E-45 T 22-04-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal L21SP4_RS05300 8b419cf86112bb054277daf575b668d0 263 Gene3D G3DSA:3.30.1330.30 2 97 1.3E-19 T 22-04-2016 IPR029064 50S ribosomal protein L30e-like L21SP4_RS05300 8b419cf86112bb054277daf575b668d0 263 Pfam PF00588 SpoU rRNA Methylase family 112 251 1.1E-33 T 22-04-2016 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 L21SP4_RS05300 8b419cf86112bb054277daf575b668d0 263 SUPERFAMILY SSF75217 103 258 4.91E-40 T 22-04-2016 IPR029028 Alpha/beta knot methyltransferases L21SP4_RS05300 8b419cf86112bb054277daf575b668d0 263 PANTHER PTHR12029 1 257 1.6E-90 T 22-04-2016 L21SP4_RS05300 8b419cf86112bb054277daf575b668d0 263 SMART SM00967 25 101 1.7E-4 T 22-04-2016 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 L21SP4_RS05300 8b419cf86112bb054277daf575b668d0 263 PANTHER PTHR12029:SF61 1 257 1.6E-90 T 22-04-2016 L21SP4_RS05300 8b419cf86112bb054277daf575b668d0 263 SUPERFAMILY SSF55315 2 97 1.01E-17 T 22-04-2016 IPR029064 50S ribosomal protein L30e-like L21SP4_RS04010 93664da7977dd9264972a0bc79bceeca 567 PANTHER PTHR30252:SF0 1 567 4.2E-184 T 22-04-2016 L21SP4_RS04010 93664da7977dd9264972a0bc79bceeca 567 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 402 519 1.2E-34 T 22-04-2016 IPR025299 CstA, C-terminal domain L21SP4_RS04010 93664da7977dd9264972a0bc79bceeca 567 Pfam PF02554 Carbon starvation protein CstA 1 345 9.6E-113 T 22-04-2016 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 L21SP4_RS04010 93664da7977dd9264972a0bc79bceeca 567 PANTHER PTHR30252 1 567 4.2E-184 T 22-04-2016 L21SP4_RS02875 9c666c856457522e9fba3192ef6cd880 313 Gene3D G3DSA:1.10.10.10 18 58 5.1E-5 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS02875 9c666c856457522e9fba3192ef6cd880 313 Pfam PF13280 WYL domain 137 307 2.1E-39 T 22-04-2016 IPR026881 WYL domain L21SP4_RS02875 9c666c856457522e9fba3192ef6cd880 313 PIRSF PIRSF016838 45 313 2.2E-20 T 22-04-2016 IPR028349 Protein PafC L21SP4_RS02875 9c666c856457522e9fba3192ef6cd880 313 PANTHER PTHR34580 18 306 3.9E-60 T 22-04-2016 L21SP4_RS02875 9c666c856457522e9fba3192ef6cd880 313 PANTHER PTHR34580:SF3 18 306 3.9E-60 T 22-04-2016 L21SP4_RS02915 0c2cf4f5e8d84ab2ad4f68c9c4084fe9 509 Pfam PF00425 chorismate binding enzyme 233 486 1.6E-100 T 22-04-2016 IPR015890 Chorismate-utilising enzyme, C-terminal L21SP4_RS02915 0c2cf4f5e8d84ab2ad4f68c9c4084fe9 509 PANTHER PTHR11236:SF9 1 497 6.6E-242 T 22-04-2016 L21SP4_RS02915 0c2cf4f5e8d84ab2ad4f68c9c4084fe9 509 Gene3D G3DSA:3.60.120.10 16 497 7.2E-180 T 22-04-2016 IPR005801 ADC synthase GO:0009058 L21SP4_RS02915 0c2cf4f5e8d84ab2ad4f68c9c4084fe9 509 SUPERFAMILY SSF56322 17 495 1.03E-162 T 22-04-2016 IPR005801 ADC synthase GO:0009058 L21SP4_RS02915 0c2cf4f5e8d84ab2ad4f68c9c4084fe9 509 Pfam PF04715 Anthranilate synthase component I, N terminal region 31 179 6.4E-35 T 22-04-2016 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058|GO:0016833 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 L21SP4_RS02915 0c2cf4f5e8d84ab2ad4f68c9c4084fe9 509 PANTHER PTHR11236 1 497 6.6E-242 T 22-04-2016 L21SP4_RS02915 0c2cf4f5e8d84ab2ad4f68c9c4084fe9 509 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 29 493 2.5E-169 T 22-04-2016 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 L21SP4_RS02915 0c2cf4f5e8d84ab2ad4f68c9c4084fe9 509 PRINTS PR00095 Anthranilate synthase component I signature 348 361 9.6E-26 T 22-04-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 L21SP4_RS02915 0c2cf4f5e8d84ab2ad4f68c9c4084fe9 509 PRINTS PR00095 Anthranilate synthase component I signature 443 457 9.6E-26 T 22-04-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 L21SP4_RS02915 0c2cf4f5e8d84ab2ad4f68c9c4084fe9 509 PRINTS PR00095 Anthranilate synthase component I signature 334 347 9.6E-26 T 22-04-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 L21SP4_RS02915 0c2cf4f5e8d84ab2ad4f68c9c4084fe9 509 PRINTS PR00095 Anthranilate synthase component I signature 428 442 9.6E-26 T 22-04-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 L21SP4_RS01865 bc73e157ff20b8fd8780a4fb36273269 594 PANTHER PTHR11780:SF0 4 562 0.0 T 22-04-2016 L21SP4_RS01865 bc73e157ff20b8fd8780a4fb36273269 594 Gene3D G3DSA:3.40.30.10 3 99 1.7E-30 T 22-04-2016 IPR012336 Thioredoxin-like fold L21SP4_RS01865 bc73e157ff20b8fd8780a4fb36273269 594 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 546 557 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site L21SP4_RS01865 bc73e157ff20b8fd8780a4fb36273269 594 SUPERFAMILY SSF52833 3 96 3.35E-22 T 22-04-2016 IPR012336 Thioredoxin-like fold L21SP4_RS01865 bc73e157ff20b8fd8780a4fb36273269 594 SMART SM00928 437 482 7.9E-20 T 22-04-2016 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 L21SP4_RS01865 bc73e157ff20b8fd8780a4fb36273269 594 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 450 461 - T 22-04-2016 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 L21SP4_RS01865 bc73e157ff20b8fd8780a4fb36273269 594 SUPERFAMILY SSF54862 540 591 3.14E-14 T 22-04-2016 L21SP4_RS01865 bc73e157ff20b8fd8780a4fb36273269 594 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 439 522 5.3E-29 T 22-04-2016 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 L21SP4_RS01865 bc73e157ff20b8fd8780a4fb36273269 594 SUPERFAMILY SSF142984 349 432 2.75E-27 T 22-04-2016 L21SP4_RS01865 bc73e157ff20b8fd8780a4fb36273269 594 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 158 327 1.6E-47 T 22-04-2016 IPR011538 NADH-ubiquinone oxidoreductase 51 kDa subunit, FMN-binding domain L21SP4_RS01865 bc73e157ff20b8fd8780a4fb36273269 594 SUPERFAMILY SSF142019 107 348 1.96E-93 T 22-04-2016 L21SP4_RS01865 bc73e157ff20b8fd8780a4fb36273269 594 Pfam PF10531 SLBB domain 351 400 4.9E-9 T 22-04-2016 IPR019554 Soluble ligand binding domain L21SP4_RS01865 bc73e157ff20b8fd8780a4fb36273269 594 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 5 78 2.4E-7 T 22-04-2016 L21SP4_RS01865 bc73e157ff20b8fd8780a4fb36273269 594 Gene3D G3DSA:3.30.70.20 539 591 1.2E-13 T 22-04-2016 L21SP4_RS01865 bc73e157ff20b8fd8780a4fb36273269 594 Pfam PF12838 4Fe-4S dicluster domain 545 590 3.7E-7 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain L21SP4_RS01865 bc73e157ff20b8fd8780a4fb36273269 594 SUPERFAMILY SSF140490 433 534 5.62E-35 T 22-04-2016 L21SP4_RS01865 bc73e157ff20b8fd8780a4fb36273269 594 PANTHER PTHR11780 4 562 0.0 T 22-04-2016 L21SP4_RS09815 5132f8d27e48cdc5fd212894ff0b789f 251 PIRSF PIRSF003073 1 251 3.7E-71 T 22-04-2016 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein L21SP4_RS09815 5132f8d27e48cdc5fd212894ff0b789f 251 PANTHER PTHR30050:SF6 5 249 5.4E-73 T 22-04-2016 L21SP4_RS09815 5132f8d27e48cdc5fd212894ff0b789f 251 SMART SM00382 99 232 6.3E-7 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS09815 5132f8d27e48cdc5fd212894ff0b789f 251 Pfam PF01695 IstB-like ATP binding protein 55 231 8.5E-50 T 22-04-2016 IPR002611 IstB-like ATP-binding protein GO:0005524 L21SP4_RS09815 5132f8d27e48cdc5fd212894ff0b789f 251 PANTHER PTHR30050 5 249 5.4E-73 T 22-04-2016 L21SP4_RS09815 5132f8d27e48cdc5fd212894ff0b789f 251 SUPERFAMILY SSF52540 95 225 2.24E-19 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS09815 5132f8d27e48cdc5fd212894ff0b789f 251 Gene3D G3DSA:3.40.50.300 89 214 4.1E-22 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS03315 5132f8d27e48cdc5fd212894ff0b789f 251 PIRSF PIRSF003073 1 251 3.7E-71 T 22-04-2016 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein L21SP4_RS03315 5132f8d27e48cdc5fd212894ff0b789f 251 PANTHER PTHR30050:SF6 5 249 5.4E-73 T 22-04-2016 L21SP4_RS03315 5132f8d27e48cdc5fd212894ff0b789f 251 SMART SM00382 99 232 6.3E-7 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS03315 5132f8d27e48cdc5fd212894ff0b789f 251 Pfam PF01695 IstB-like ATP binding protein 55 231 8.5E-50 T 22-04-2016 IPR002611 IstB-like ATP-binding protein GO:0005524 L21SP4_RS03315 5132f8d27e48cdc5fd212894ff0b789f 251 PANTHER PTHR30050 5 249 5.4E-73 T 22-04-2016 L21SP4_RS03315 5132f8d27e48cdc5fd212894ff0b789f 251 SUPERFAMILY SSF52540 95 225 2.24E-19 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS03315 5132f8d27e48cdc5fd212894ff0b789f 251 Gene3D G3DSA:3.40.50.300 89 214 4.1E-22 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS01845 5132f8d27e48cdc5fd212894ff0b789f 251 PIRSF PIRSF003073 1 251 3.7E-71 T 22-04-2016 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein L21SP4_RS01845 5132f8d27e48cdc5fd212894ff0b789f 251 PANTHER PTHR30050:SF6 5 249 5.4E-73 T 22-04-2016 L21SP4_RS01845 5132f8d27e48cdc5fd212894ff0b789f 251 SMART SM00382 99 232 6.3E-7 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS01845 5132f8d27e48cdc5fd212894ff0b789f 251 Pfam PF01695 IstB-like ATP binding protein 55 231 8.5E-50 T 22-04-2016 IPR002611 IstB-like ATP-binding protein GO:0005524 L21SP4_RS01845 5132f8d27e48cdc5fd212894ff0b789f 251 PANTHER PTHR30050 5 249 5.4E-73 T 22-04-2016 L21SP4_RS01845 5132f8d27e48cdc5fd212894ff0b789f 251 SUPERFAMILY SSF52540 95 225 2.24E-19 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS01845 5132f8d27e48cdc5fd212894ff0b789f 251 Gene3D G3DSA:3.40.50.300 89 214 4.1E-22 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS09705 5132f8d27e48cdc5fd212894ff0b789f 251 PIRSF PIRSF003073 1 251 3.7E-71 T 22-04-2016 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein L21SP4_RS09705 5132f8d27e48cdc5fd212894ff0b789f 251 PANTHER PTHR30050:SF6 5 249 5.4E-73 T 22-04-2016 L21SP4_RS09705 5132f8d27e48cdc5fd212894ff0b789f 251 SMART SM00382 99 232 6.3E-7 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS09705 5132f8d27e48cdc5fd212894ff0b789f 251 Pfam PF01695 IstB-like ATP binding protein 55 231 8.5E-50 T 22-04-2016 IPR002611 IstB-like ATP-binding protein GO:0005524 L21SP4_RS09705 5132f8d27e48cdc5fd212894ff0b789f 251 PANTHER PTHR30050 5 249 5.4E-73 T 22-04-2016 L21SP4_RS09705 5132f8d27e48cdc5fd212894ff0b789f 251 SUPERFAMILY SSF52540 95 225 2.24E-19 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS09705 5132f8d27e48cdc5fd212894ff0b789f 251 Gene3D G3DSA:3.40.50.300 89 214 4.1E-22 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS08000 5244fb6d910a2e1c6c289f02f8490699 462 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 174 233 3.8E-13 T 22-04-2016 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain L21SP4_RS08000 5244fb6d910a2e1c6c289f02f8490699 462 Gene3D G3DSA:1.10.3090.10 147 341 7.6E-47 T 22-04-2016 L21SP4_RS08000 5244fb6d910a2e1c6c289f02f8490699 462 Gene3D G3DSA:1.10.3090.10 398 419 7.6E-47 T 22-04-2016 L21SP4_RS08000 5244fb6d910a2e1c6c289f02f8490699 462 SUPERFAMILY SSF81301 8 142 1.53E-37 T 22-04-2016 L21SP4_RS08000 5244fb6d910a2e1c6c289f02f8490699 462 Gene3D G3DSA:3.30.460.10 10 146 2.9E-44 T 22-04-2016 L21SP4_RS08000 5244fb6d910a2e1c6c289f02f8490699 462 Pfam PF01743 Poly A polymerase head domain 26 146 3.1E-35 T 22-04-2016 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 L21SP4_RS08000 5244fb6d910a2e1c6c289f02f8490699 462 SUPERFAMILY SSF81891 319 451 1.24E-51 T 22-04-2016 L21SP4_RS08000 5244fb6d910a2e1c6c289f02f8490699 462 SUPERFAMILY SSF81891 144 292 1.24E-51 T 22-04-2016 L21SP4_RS08000 5244fb6d910a2e1c6c289f02f8490699 462 Pfam PF01966 HD domain 252 349 2.1E-7 T 22-04-2016 IPR006674 HD domain L21SP4_RS08000 5244fb6d910a2e1c6c289f02f8490699 462 PANTHER PTHR13734:SF5 14 450 5.2E-88 T 22-04-2016 L21SP4_RS08000 5244fb6d910a2e1c6c289f02f8490699 462 PANTHER PTHR13734 14 450 5.2E-88 T 22-04-2016 L21SP4_RS09180 6d7bd47d14d650d2f0eb8e392e29cf78 249 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 219 243 7.7E-4 T 22-04-2016 IPR013424 PEP-CTERM protein-sorting domain L21SP4_RS09180 6d7bd47d14d650d2f0eb8e392e29cf78 249 Pfam PF07589 PEP-CTERM motif 218 240 4.4E-4 T 22-04-2016 IPR013424 PEP-CTERM protein-sorting domain L21SP4_RS01050 021312856ca803940312ba6cc1f6ee71 233 PANTHER PTHR11727 1 228 8.5E-57 T 22-04-2016 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm L21SP4_RS01050 021312856ca803940312ba6cc1f6ee71 233 Pfam PF00398 Ribosomal RNA adenine dimethylase 2 201 4.6E-44 T 22-04-2016 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm L21SP4_RS01050 021312856ca803940312ba6cc1f6ee71 233 SUPERFAMILY SSF53335 2 229 3.41E-52 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS01050 021312856ca803940312ba6cc1f6ee71 233 Gene3D G3DSA:3.40.50.150 2 169 1.1E-49 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS01050 021312856ca803940312ba6cc1f6ee71 233 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 2 228 9.4E-56 T 22-04-2016 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 L21SP4_RS01050 021312856ca803940312ba6cc1f6ee71 233 Gene3D G3DSA:1.10.8.100 180 229 3.6E-9 T 22-04-2016 IPR023165 rRNA adenine dimethylase-like L21SP4_RS01050 021312856ca803940312ba6cc1f6ee71 233 SMART SM00650 1 168 6.9E-58 T 22-04-2016 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 L21SP4_RS01050 021312856ca803940312ba6cc1f6ee71 233 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 13 40 - T 22-04-2016 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 L21SP4_RS02715 e1d250cf5c685cf21fb28f14e02119c5 288 PANTHER PTHR13754 4 280 9.8E-71 T 22-04-2016 L21SP4_RS02715 e1d250cf5c685cf21fb28f14e02119c5 288 Pfam PF00753 Metallo-beta-lactamase superfamily 26 128 4.4E-10 T 22-04-2016 IPR001279 Metallo-beta-lactamase L21SP4_RS02715 e1d250cf5c685cf21fb28f14e02119c5 288 SUPERFAMILY SSF56281 10 259 4.19E-28 T 22-04-2016 IPR001279 Metallo-beta-lactamase L21SP4_RS02715 e1d250cf5c685cf21fb28f14e02119c5 288 Gene3D G3DSA:3.60.15.10 2 269 1.6E-28 T 22-04-2016 IPR001279 Metallo-beta-lactamase L21SP4_RS02715 e1d250cf5c685cf21fb28f14e02119c5 288 SMART SM00849 24 220 0.0098 T 22-04-2016 IPR001279 Metallo-beta-lactamase L21SP4_RS02715 e1d250cf5c685cf21fb28f14e02119c5 288 PANTHER PTHR13754:SF13 4 280 9.8E-71 T 22-04-2016 L21SP4_RS07115 1f726d8237bd60ab88e5dce8d6421079 478 Gene3D G3DSA:2.40.50.140 65 188 1.3E-45 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold L21SP4_RS07115 1f726d8237bd60ab88e5dce8d6421079 478 TIGRFAM TIGR00767 rho: transcription termination factor Rho 65 476 5.7E-199 T 22-04-2016 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 L21SP4_RS07115 1f726d8237bd60ab88e5dce8d6421079 478 Hamap MF_01884 Transcription termination factor Rho [rho]. 63 478 211.062 T 22-04-2016 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 L21SP4_RS07115 1f726d8237bd60ab88e5dce8d6421079 478 PANTHER PTHR15184 162 477 5.8E-171 T 22-04-2016 L21SP4_RS07115 1f726d8237bd60ab88e5dce8d6421079 478 SMART SM00382 229 414 4.8E-11 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS07115 1f726d8237bd60ab88e5dce8d6421079 478 Pfam PF07498 Rho termination factor, N-terminal domain 67 109 3.2E-12 T 22-04-2016 IPR011112 Rho termination factor, N-terminal GO:0006353 L21SP4_RS07115 1f726d8237bd60ab88e5dce8d6421079 478 SUPERFAMILY SSF52540 152 430 1.29E-67 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS07115 1f726d8237bd60ab88e5dce8d6421079 478 PANTHER PTHR15184:SF34 162 477 5.8E-171 T 22-04-2016 L21SP4_RS07115 1f726d8237bd60ab88e5dce8d6421079 478 SMART SM00959 67 109 9.6E-13 T 22-04-2016 IPR011112 Rho termination factor, N-terminal GO:0006353 L21SP4_RS07115 1f726d8237bd60ab88e5dce8d6421079 478 SMART SM00357 114 180 4.7E-13 T 22-04-2016 IPR011129 Cold shock protein GO:0003676 L21SP4_RS07115 1f726d8237bd60ab88e5dce8d6421079 478 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 218 422 5.6E-24 T 22-04-2016 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 L21SP4_RS07115 1f726d8237bd60ab88e5dce8d6421079 478 Gene3D G3DSA:3.40.50.300 192 474 4.4E-97 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS07115 1f726d8237bd60ab88e5dce8d6421079 478 SUPERFAMILY SSF50249 112 187 1.88E-25 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold L21SP4_RS07115 1f726d8237bd60ab88e5dce8d6421079 478 Pfam PF07497 Rho termination factor, RNA-binding domain 114 187 1.5E-30 T 22-04-2016 IPR011113 Rho termination factor, RNA-binding GO:0003723|GO:0006353 L21SP4_RS07115 1f726d8237bd60ab88e5dce8d6421079 478 SUPERFAMILY SSF68912 63 109 1.92E-9 T 22-04-2016 IPR011112 Rho termination factor, N-terminal GO:0006353 L21SP4_RS00610 7694b0fa37eeb7b3865c8a6a3d45e9b5 152 PANTHER PTHR33937:SF2 19 148 2.3E-16 T 22-04-2016 L21SP4_RS00610 7694b0fa37eeb7b3865c8a6a3d45e9b5 152 Gene3D G3DSA:3.30.420.130 19 132 2.6E-25 T 22-04-2016 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis L21SP4_RS00610 7694b0fa37eeb7b3865c8a6a3d45e9b5 152 SUPERFAMILY SSF53146 19 138 6.93E-25 T 22-04-2016 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis L21SP4_RS00610 7694b0fa37eeb7b3865c8a6a3d45e9b5 152 PANTHER PTHR33937 19 148 2.3E-16 T 22-04-2016 L21SP4_RS00610 7694b0fa37eeb7b3865c8a6a3d45e9b5 152 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 31 121 1.6E-18 T 22-04-2016 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis L21SP4_RS04930 3240df1f478455b7695339e0add7f94c 342 PANTHER PTHR33055 7 336 9.4E-30 T 22-04-2016 L21SP4_RS04930 3240df1f478455b7695339e0add7f94c 342 Pfam PF01548 Transposase 12 156 7.8E-14 T 22-04-2016 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 L21SP4_RS04930 3240df1f478455b7695339e0add7f94c 342 PANTHER PTHR33055:SF3 7 336 9.4E-30 T 22-04-2016 L21SP4_RS04930 3240df1f478455b7695339e0add7f94c 342 Pfam PF02371 Transposase IS116/IS110/IS902 family 220 303 7.3E-12 T 22-04-2016 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 L21SP4_RS07025 3240df1f478455b7695339e0add7f94c 342 PANTHER PTHR33055 7 336 9.4E-30 T 22-04-2016 L21SP4_RS07025 3240df1f478455b7695339e0add7f94c 342 Pfam PF01548 Transposase 12 156 7.8E-14 T 22-04-2016 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 L21SP4_RS07025 3240df1f478455b7695339e0add7f94c 342 PANTHER PTHR33055:SF3 7 336 9.4E-30 T 22-04-2016 L21SP4_RS07025 3240df1f478455b7695339e0add7f94c 342 Pfam PF02371 Transposase IS116/IS110/IS902 family 220 303 7.3E-12 T 22-04-2016 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 L21SP4_RS11325 3240df1f478455b7695339e0add7f94c 342 PANTHER PTHR33055 7 336 9.4E-30 T 22-04-2016 L21SP4_RS11325 3240df1f478455b7695339e0add7f94c 342 Pfam PF01548 Transposase 12 156 7.8E-14 T 22-04-2016 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 L21SP4_RS11325 3240df1f478455b7695339e0add7f94c 342 PANTHER PTHR33055:SF3 7 336 9.4E-30 T 22-04-2016 L21SP4_RS11325 3240df1f478455b7695339e0add7f94c 342 Pfam PF02371 Transposase IS116/IS110/IS902 family 220 303 7.3E-12 T 22-04-2016 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 L21SP4_RS10055 3240df1f478455b7695339e0add7f94c 342 PANTHER PTHR33055 7 336 9.4E-30 T 22-04-2016 L21SP4_RS10055 3240df1f478455b7695339e0add7f94c 342 Pfam PF01548 Transposase 12 156 7.8E-14 T 22-04-2016 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 L21SP4_RS10055 3240df1f478455b7695339e0add7f94c 342 PANTHER PTHR33055:SF3 7 336 9.4E-30 T 22-04-2016 L21SP4_RS10055 3240df1f478455b7695339e0add7f94c 342 Pfam PF02371 Transposase IS116/IS110/IS902 family 220 303 7.3E-12 T 22-04-2016 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 L21SP4_RS10210 8d03fae8b6d1de146219b4b0b4d389b5 478 Pfam PF04963 Sigma-54 factor, core binding domain 119 304 4.5E-53 T 22-04-2016 IPR007046 RNA polymerase sigma factor 54, core-binding GO:0003677|GO:0006352 L21SP4_RS10210 8d03fae8b6d1de146219b4b0b4d389b5 478 Pfam PF00309 Sigma-54 factor, Activator interacting domain (AID) 8 52 1.0E-10 T 22-04-2016 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 L21SP4_RS10210 8d03fae8b6d1de146219b4b0b4d389b5 478 ProSitePatterns PS00718 Sigma-54 factors family signature 2. 457 464 - T 22-04-2016 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 L21SP4_RS10210 8d03fae8b6d1de146219b4b0b4d389b5 478 PANTHER PTHR32248 3 478 9.0E-133 T 22-04-2016 L21SP4_RS10210 8d03fae8b6d1de146219b4b0b4d389b5 478 Gene3D G3DSA:1.10.260.40 368 390 2.8E-4 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 L21SP4_RS10210 8d03fae8b6d1de146219b4b0b4d389b5 478 PRINTS PR00045 Sigma-54 factor signature 394 405 2.4E-27 T 22-04-2016 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 L21SP4_RS10210 8d03fae8b6d1de146219b4b0b4d389b5 478 PRINTS PR00045 Sigma-54 factor signature 378 390 2.4E-27 T 22-04-2016 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 L21SP4_RS10210 8d03fae8b6d1de146219b4b0b4d389b5 478 PRINTS PR00045 Sigma-54 factor signature 452 470 2.4E-27 T 22-04-2016 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 L21SP4_RS10210 8d03fae8b6d1de146219b4b0b4d389b5 478 PRINTS PR00045 Sigma-54 factor signature 189 206 2.4E-27 T 22-04-2016 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 L21SP4_RS10210 8d03fae8b6d1de146219b4b0b4d389b5 478 Pfam PF04552 Sigma-54, DNA binding domain 319 477 4.0E-60 T 22-04-2016 IPR007634 RNA polymerase sigma factor 54, DNA-binding L21SP4_RS10210 8d03fae8b6d1de146219b4b0b4d389b5 478 PIRSF PIRSF000774 2 478 8.3E-140 T 22-04-2016 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 L21SP4_RS10210 8d03fae8b6d1de146219b4b0b4d389b5 478 PANTHER PTHR32248:SF4 3 478 9.0E-133 T 22-04-2016 L21SP4_RS10210 8d03fae8b6d1de146219b4b0b4d389b5 478 TIGRFAM TIGR02395 rpoN_sigma: RNA polymerase sigma-54 factor 12 476 1.9E-125 T 22-04-2016 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 L21SP4_RS03245 488a637e68d9b5fd21a6a8aab8146496 700 PANTHER PTHR35149 11 573 7.4E-110 T 22-04-2016 L21SP4_RS03245 488a637e68d9b5fd21a6a8aab8146496 700 PANTHER PTHR35149:SF2 11 573 7.4E-110 T 22-04-2016 L21SP4_RS03245 488a637e68d9b5fd21a6a8aab8146496 700 Pfam PF03235 Protein of unknown function DUF262 10 221 4.5E-32 T 22-04-2016 IPR004919 Domain of unknown function DUF262 L21SP4_RS03245 488a637e68d9b5fd21a6a8aab8146496 700 Pfam PF07510 Protein of unknown function (DUF1524) 413 549 4.2E-27 T 22-04-2016 IPR011089 Domain of unknown function DUF1524 L21SP4_RS08720 f05abfc79b6a09856182277b846dca7f 298 SMART SM00382 90 269 2.5E-8 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS08720 f05abfc79b6a09856182277b846dca7f 298 SUPERFAMILY SSF52540 88 292 1.18E-44 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS08720 f05abfc79b6a09856182277b846dca7f 298 PANTHER PTHR11564:SF16 1 296 1.9E-102 T 22-04-2016 L21SP4_RS08720 f05abfc79b6a09856182277b846dca7f 298 PANTHER PTHR11564 1 296 1.9E-102 T 22-04-2016 L21SP4_RS08720 f05abfc79b6a09856182277b846dca7f 298 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 265 278 - T 22-04-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: REACT_15380 L21SP4_RS08720 f05abfc79b6a09856182277b846dca7f 298 Pfam PF00448 SRP54-type protein, GTPase domain 92 291 7.8E-68 T 22-04-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: REACT_15380 L21SP4_RS08720 f05abfc79b6a09856182277b846dca7f 298 SMART SM00962 91 292 4.3E-100 T 22-04-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: REACT_15380 L21SP4_RS08720 f05abfc79b6a09856182277b846dca7f 298 Gene3D G3DSA:1.20.120.140 29 101 2.6E-17 T 22-04-2016 L21SP4_RS08720 f05abfc79b6a09856182277b846dca7f 298 Gene3D G3DSA:3.40.50.300 102 292 4.4E-71 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS08720 f05abfc79b6a09856182277b846dca7f 298 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 29 291 1.2E-83 T 22-04-2016 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 L21SP4_RS08720 f05abfc79b6a09856182277b846dca7f 298 SUPERFAMILY SSF47364 4 58 7.85E-8 T 22-04-2016 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: REACT_15380 L21SP4_RS08720 f05abfc79b6a09856182277b846dca7f 298 SMART SM00963 4 77 0.0088 T 22-04-2016 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: REACT_15380 L21SP4_RS11290 b37f8e9e9347c22d816b651e67c8086e 629 SUPERFAMILY SSF56235 15 250 1.54E-58 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal L21SP4_RS11290 b37f8e9e9347c22d816b651e67c8086e 629 Pfam PF00733 Asparagine synthase 269 611 5.6E-78 T 22-04-2016 IPR001962 Asparagine synthase GO:0004066|GO:0006529 L21SP4_RS11290 b37f8e9e9347c22d816b651e67c8086e 629 Pfam PF13537 Glutamine amidotransferase domain 71 193 1.7E-45 T 22-04-2016 IPR017932 Glutamine amidotransferase type 2 domain L21SP4_RS11290 b37f8e9e9347c22d816b651e67c8086e 629 PANTHER PTHR11772:SF10 17 410 2.6E-135 T 22-04-2016 L21SP4_RS11290 b37f8e9e9347c22d816b651e67c8086e 629 PANTHER PTHR11772:SF10 482 578 2.6E-135 T 22-04-2016 L21SP4_RS11290 b37f8e9e9347c22d816b651e67c8086e 629 PANTHER PTHR11772 17 410 2.6E-135 T 22-04-2016 L21SP4_RS11290 b37f8e9e9347c22d816b651e67c8086e 629 PANTHER PTHR11772 482 578 2.6E-135 T 22-04-2016 L21SP4_RS11290 b37f8e9e9347c22d816b651e67c8086e 629 SUPERFAMILY SSF52402 487 590 2.12E-68 T 22-04-2016 L21SP4_RS11290 b37f8e9e9347c22d816b651e67c8086e 629 SUPERFAMILY SSF52402 245 406 2.12E-68 T 22-04-2016 L21SP4_RS11290 b37f8e9e9347c22d816b651e67c8086e 629 Gene3D G3DSA:3.40.50.620 494 585 1.9E-70 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP4_RS11290 b37f8e9e9347c22d816b651e67c8086e 629 Gene3D G3DSA:3.40.50.620 250 412 1.9E-70 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP4_RS11290 b37f8e9e9347c22d816b651e67c8086e 629 Gene3D G3DSA:3.60.20.10 16 249 3.3E-67 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal L21SP4_RS11290 b37f8e9e9347c22d816b651e67c8086e 629 PIRSF PIRSF001589 16 617 1.4E-152 T 22-04-2016 L21SP4_RS11290 b37f8e9e9347c22d816b651e67c8086e 629 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 17 571 1.6E-138 T 22-04-2016 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|UniPathway: UPA00134 L21SP4_RS07770 89505d2d952cc7baf065a212f9ea3757 331 Gene3D G3DSA:3.40.50.300 114 330 3.7E-57 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS07770 89505d2d952cc7baf065a212f9ea3757 331 SUPERFAMILY SSF52540 5 329 5.57E-56 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS07770 89505d2d952cc7baf065a212f9ea3757 331 PANTHER PTHR30486:SF5 1 331 6.0E-114 T 22-04-2016 L21SP4_RS07770 89505d2d952cc7baf065a212f9ea3757 331 Pfam PF00437 Type II/IV secretion system protein 70 270 7.5E-39 T 22-04-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 L21SP4_RS07770 89505d2d952cc7baf065a212f9ea3757 331 PANTHER PTHR30486 1 331 6.0E-114 T 22-04-2016 L21SP4_RS07770 89505d2d952cc7baf065a212f9ea3757 331 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 198 212 - T 22-04-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 L21SP4_RS07770 89505d2d952cc7baf065a212f9ea3757 331 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 5 330 2.9E-119 T 22-04-2016 IPR006321 Pilus retraction protein PilT GO:0005524|GO:0006810 L21SP4_RS10775 791149bfedd2594287f2cd9f56a83223 483 PANTHER PTHR10342:SF199 1 130 7.6E-148 T 22-04-2016 L21SP4_RS10775 791149bfedd2594287f2cd9f56a83223 483 PANTHER PTHR10342:SF199 152 296 7.6E-148 T 22-04-2016 L21SP4_RS10775 791149bfedd2594287f2cd9f56a83223 483 PANTHER PTHR10342:SF199 316 481 7.6E-148 T 22-04-2016 L21SP4_RS10775 791149bfedd2594287f2cd9f56a83223 483 Pfam PF00884 Sulfatase 29 370 3.9E-68 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS10775 791149bfedd2594287f2cd9f56a83223 483 ProSitePatterns PS00149 Sulfatases signature 2. 119 129 - T 22-04-2016 IPR024607 Sulfatase, conserved site L21SP4_RS10775 791149bfedd2594287f2cd9f56a83223 483 Gene3D G3DSA:3.40.720.10 28 405 4.4E-107 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS10775 791149bfedd2594287f2cd9f56a83223 483 Gene3D G3DSA:3.30.1120.10 406 467 2.2E-18 T 22-04-2016 L21SP4_RS10775 791149bfedd2594287f2cd9f56a83223 483 PANTHER PTHR10342 1 130 7.6E-148 T 22-04-2016 L21SP4_RS10775 791149bfedd2594287f2cd9f56a83223 483 PANTHER PTHR10342 152 296 7.6E-148 T 22-04-2016 L21SP4_RS10775 791149bfedd2594287f2cd9f56a83223 483 PANTHER PTHR10342 316 481 7.6E-148 T 22-04-2016 L21SP4_RS10775 791149bfedd2594287f2cd9f56a83223 483 SUPERFAMILY SSF53649 163 458 1.38E-121 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS10775 791149bfedd2594287f2cd9f56a83223 483 SUPERFAMILY SSF53649 27 135 1.38E-121 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS06335 86befcdb5af3b719574af57d4b5c501c 512 SUPERFAMILY SSF55781 4 164 3.27E-25 T 22-04-2016 IPR029016 GAF domain-like L21SP4_RS06335 86befcdb5af3b719574af57d4b5c501c 512 SUPERFAMILY SSF46689 410 507 7.62E-9 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS06335 86befcdb5af3b719574af57d4b5c501c 512 Gene3D G3DSA:1.10.10.60 456 507 1.5E-7 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS06335 86befcdb5af3b719574af57d4b5c501c 512 Gene3D G3DSA:3.30.450.40 7 175 4.9E-35 T 22-04-2016 IPR029016 GAF domain-like L21SP4_RS06335 86befcdb5af3b719574af57d4b5c501c 512 SMART SM00382 217 361 1.0E-11 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS06335 86befcdb5af3b719574af57d4b5c501c 512 Pfam PF00158 Sigma-54 interaction domain 197 363 2.7E-72 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 L21SP4_RS06335 86befcdb5af3b719574af57d4b5c501c 512 PANTHER PTHR32071 146 512 1.3E-163 T 22-04-2016 L21SP4_RS06335 86befcdb5af3b719574af57d4b5c501c 512 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 221 234 - T 22-04-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 L21SP4_RS06335 86befcdb5af3b719574af57d4b5c501c 512 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 410 419 - T 22-04-2016 IPR025944 Sigma-54 interaction domain, conserved site L21SP4_RS06335 86befcdb5af3b719574af57d4b5c501c 512 SMART SM00065 25 174 2.5E-18 T 22-04-2016 IPR003018 GAF domain GO:0005515 L21SP4_RS06335 86befcdb5af3b719574af57d4b5c501c 512 Gene3D G3DSA:3.40.50.300 195 369 2.2E-60 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS06335 86befcdb5af3b719574af57d4b5c501c 512 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 470 487 2.2E-7 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 L21SP4_RS06335 86befcdb5af3b719574af57d4b5c501c 512 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 487 507 2.2E-7 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 L21SP4_RS06335 86befcdb5af3b719574af57d4b5c501c 512 Pfam PF13185 GAF domain 25 164 1.1E-13 T 22-04-2016 IPR003018 GAF domain GO:0005515 L21SP4_RS06335 86befcdb5af3b719574af57d4b5c501c 512 SUPERFAMILY SSF52540 196 439 4.73E-74 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS06335 86befcdb5af3b719574af57d4b5c501c 512 Gene3D G3DSA:1.10.8.60 370 447 3.8E-28 T 22-04-2016 L21SP4_RS06335 86befcdb5af3b719574af57d4b5c501c 512 Pfam PF02954 Bacterial regulatory protein, Fis family 468 503 7.0E-6 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 L21SP4_RS11355 ddf7100fe084d95ed165caf9ae7a2c7e 588 Pfam PF03600 Citrate transporter 16 533 4.2E-50 T 22-04-2016 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 L21SP4_RS11355 ddf7100fe084d95ed165caf9ae7a2c7e 588 SUPERFAMILY SSF116726 295 384 4.19E-18 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 L21SP4_RS11355 ddf7100fe084d95ed165caf9ae7a2c7e 588 Pfam PF02080 TrkA-C domain 308 365 4.0E-10 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 L21SP4_RS11355 ddf7100fe084d95ed165caf9ae7a2c7e 588 Pfam PF02080 TrkA-C domain 219 285 4.1E-13 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 L21SP4_RS11355 ddf7100fe084d95ed165caf9ae7a2c7e 588 ProSitePatterns PS01271 Sodium:sulfate symporter family signature. 536 552 - T 22-04-2016 IPR031312 Sodium/sulphate symporter, conserved site L21SP4_RS11355 ddf7100fe084d95ed165caf9ae7a2c7e 588 PANTHER PTHR10283 349 588 5.5E-120 T 22-04-2016 L21SP4_RS11355 ddf7100fe084d95ed165caf9ae7a2c7e 588 PANTHER PTHR10283 6 206 5.5E-120 T 22-04-2016 L21SP4_RS11355 ddf7100fe084d95ed165caf9ae7a2c7e 588 PANTHER PTHR10283 293 317 5.5E-120 T 22-04-2016 L21SP4_RS11355 ddf7100fe084d95ed165caf9ae7a2c7e 588 SUPERFAMILY SSF116726 207 290 3.92E-18 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 L21SP4_RS11355 ddf7100fe084d95ed165caf9ae7a2c7e 588 PANTHER PTHR10283:SF79 349 588 5.5E-120 T 22-04-2016 L21SP4_RS11355 ddf7100fe084d95ed165caf9ae7a2c7e 588 PANTHER PTHR10283:SF79 6 206 5.5E-120 T 22-04-2016 L21SP4_RS11355 ddf7100fe084d95ed165caf9ae7a2c7e 588 PANTHER PTHR10283:SF79 293 317 5.5E-120 T 22-04-2016 L21SP4_RS11355 ddf7100fe084d95ed165caf9ae7a2c7e 588 Gene3D G3DSA:3.30.70.1450 215 291 2.2E-17 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 L21SP4_RS11355 ddf7100fe084d95ed165caf9ae7a2c7e 588 Gene3D G3DSA:3.30.70.1450 304 385 3.0E-18 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 L21SP4_RS03500 870b451a0e278bb7d43c661d7315276c 408 SUPERFAMILY SSF111369 75 251 1.7E-19 T 22-04-2016 L21SP4_RS03500 870b451a0e278bb7d43c661d7315276c 408 Gene3D G3DSA:2.40.50.100 86 120 2.0E-11 T 22-04-2016 L21SP4_RS03500 870b451a0e278bb7d43c661d7315276c 408 Gene3D G3DSA:2.40.50.100 202 234 2.0E-11 T 22-04-2016 L21SP4_RS03500 870b451a0e278bb7d43c661d7315276c 408 PANTHER PTHR30469 13 407 1.4E-42 T 22-04-2016 L21SP4_RS03500 870b451a0e278bb7d43c661d7315276c 408 Pfam PF13437 HlyD family secretion protein 205 303 5.7E-10 T 22-04-2016 L21SP4_RS03500 870b451a0e278bb7d43c661d7315276c 408 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 60 399 2.8E-35 T 22-04-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 L21SP4_RS04145 41d7bf0797d6c8ad93a52796f8ab7878 521 PANTHER PTHR11206:SF90 504 514 4.2E-55 T 22-04-2016 L21SP4_RS04145 41d7bf0797d6c8ad93a52796f8ab7878 521 PANTHER PTHR11206:SF90 66 84 4.2E-55 T 22-04-2016 L21SP4_RS04145 41d7bf0797d6c8ad93a52796f8ab7878 521 PANTHER PTHR11206:SF90 214 443 4.2E-55 T 22-04-2016 L21SP4_RS04145 41d7bf0797d6c8ad93a52796f8ab7878 521 Pfam PF03023 MviN-like protein 26 464 1.2E-99 T 22-04-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ L21SP4_RS04145 41d7bf0797d6c8ad93a52796f8ab7878 521 PRINTS PR01806 Virulence factor MviN signature 354 373 3.5E-49 T 22-04-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ L21SP4_RS04145 41d7bf0797d6c8ad93a52796f8ab7878 521 PRINTS PR01806 Virulence factor MviN signature 410 427 3.5E-49 T 22-04-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ L21SP4_RS04145 41d7bf0797d6c8ad93a52796f8ab7878 521 PRINTS PR01806 Virulence factor MviN signature 50 66 3.5E-49 T 22-04-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ L21SP4_RS04145 41d7bf0797d6c8ad93a52796f8ab7878 521 PRINTS PR01806 Virulence factor MviN signature 31 50 3.5E-49 T 22-04-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ L21SP4_RS04145 41d7bf0797d6c8ad93a52796f8ab7878 521 PRINTS PR01806 Virulence factor MviN signature 150 171 3.5E-49 T 22-04-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ L21SP4_RS04145 41d7bf0797d6c8ad93a52796f8ab7878 521 PRINTS PR01806 Virulence factor MviN signature 256 282 3.5E-49 T 22-04-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ L21SP4_RS04145 41d7bf0797d6c8ad93a52796f8ab7878 521 PRINTS PR01806 Virulence factor MviN signature 126 150 3.5E-49 T 22-04-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ L21SP4_RS04145 41d7bf0797d6c8ad93a52796f8ab7878 521 PIRSF PIRSF002869 1 515 2.1E-132 T 22-04-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ L21SP4_RS04145 41d7bf0797d6c8ad93a52796f8ab7878 521 PANTHER PTHR11206 504 514 4.2E-55 T 22-04-2016 L21SP4_RS04145 41d7bf0797d6c8ad93a52796f8ab7878 521 PANTHER PTHR11206 66 84 4.2E-55 T 22-04-2016 L21SP4_RS04145 41d7bf0797d6c8ad93a52796f8ab7878 521 PANTHER PTHR11206 214 443 4.2E-55 T 22-04-2016 L21SP4_RS04145 41d7bf0797d6c8ad93a52796f8ab7878 521 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 2 506 9.6E-109 T 22-04-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ L21SP4_RS00320 71edb8b0daa38336639fdc5a8dd03267 133 PANTHER PTHR33515 3 109 1.6E-26 T 22-04-2016 L21SP4_RS00320 71edb8b0daa38336639fdc5a8dd03267 133 Gene3D G3DSA:3.30.300.20 3 109 1.6E-24 T 22-04-2016 IPR015946 K homology domain-like, alpha/beta L21SP4_RS00320 71edb8b0daa38336639fdc5a8dd03267 133 Pfam PF02033 Ribosome-binding factor A 3 104 1.1E-22 T 22-04-2016 IPR000238 Ribosome-binding factor A GO:0006364 L21SP4_RS00320 71edb8b0daa38336639fdc5a8dd03267 133 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 3 109 4.7E-22 T 22-04-2016 IPR000238 Ribosome-binding factor A GO:0006364 L21SP4_RS00320 71edb8b0daa38336639fdc5a8dd03267 133 ProSitePatterns PS01319 Ribosome-binding factor A signature. 70 91 - T 22-04-2016 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 L21SP4_RS00320 71edb8b0daa38336639fdc5a8dd03267 133 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 1 111 14.631 T 22-04-2016 IPR000238 Ribosome-binding factor A GO:0006364 L21SP4_RS00320 71edb8b0daa38336639fdc5a8dd03267 133 SUPERFAMILY SSF89919 2 107 5.63E-24 T 22-04-2016 IPR023799 Ribosome-binding factor A domain L21SP4_RS00320 71edb8b0daa38336639fdc5a8dd03267 133 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 3 91 3.0E-10 T 22-04-2016 IPR000238 Ribosome-binding factor A GO:0006364 L21SP4_RS07170 93aebbe30d00a86e9271720f43953a3c 393 TIGRFAM TIGR01047 nspC: carboxynorspermidine decarboxylase 11 392 3.7E-129 T 22-04-2016 IPR005730 Carboxynorspermidine decarboxylase KEGG: 00330+4.1.1.96|MetaCyc: PWY-6562 L21SP4_RS07170 93aebbe30d00a86e9271720f43953a3c 393 Gene3D G3DSA:2.40.37.10 198 387 1.1E-40 T 22-04-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 L21SP4_RS07170 93aebbe30d00a86e9271720f43953a3c 393 PANTHER PTHR11482:SF38 1 393 6.5E-148 T 22-04-2016 L21SP4_RS07170 93aebbe30d00a86e9271720f43953a3c 393 PIRSF PIRSF038941 1 393 5.5E-147 T 22-04-2016 IPR005730 Carboxynorspermidine decarboxylase KEGG: 00330+4.1.1.96|MetaCyc: PWY-6562 L21SP4_RS07170 93aebbe30d00a86e9271720f43953a3c 393 PANTHER PTHR11482 1 393 6.5E-148 T 22-04-2016 L21SP4_RS07170 93aebbe30d00a86e9271720f43953a3c 393 SUPERFAMILY SSF51419 17 252 4.09E-40 T 22-04-2016 IPR029066 PLP-binding barrel L21SP4_RS07170 93aebbe30d00a86e9271720f43953a3c 393 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 255 368 6.2E-11 T 22-04-2016 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 Reactome: REACT_13 L21SP4_RS07170 93aebbe30d00a86e9271720f43953a3c 393 SUPERFAMILY SSF50621 219 382 6.28E-29 T 22-04-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 L21SP4_RS06950 271b4e0da6b9ca5b55ccf35c1b15c70a 261 PANTHER PTHR11280 1 258 1.2E-127 T 22-04-2016 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|UniPathway: UPA00629 L21SP4_RS06950 271b4e0da6b9ca5b55ccf35c1b15c70a 261 TIGRFAM TIGR00502 nagB: glucosamine-6-phosphate deaminase 1 243 7.2E-91 T 22-04-2016 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|UniPathway: UPA00629 L21SP4_RS06950 271b4e0da6b9ca5b55ccf35c1b15c70a 261 Hamap MF_01241 Glucosamine-6-phosphate deaminase [nagB]. 1 241 41.81 T 22-04-2016 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|UniPathway: UPA00629 L21SP4_RS06950 271b4e0da6b9ca5b55ccf35c1b15c70a 261 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 18 224 6.8E-21 T 22-04-2016 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 L21SP4_RS06950 271b4e0da6b9ca5b55ccf35c1b15c70a 261 Gene3D G3DSA:3.40.50.1360 1 256 3.9E-100 T 22-04-2016 L21SP4_RS06950 271b4e0da6b9ca5b55ccf35c1b15c70a 261 SUPERFAMILY SSF100950 1 252 2.37E-95 T 22-04-2016 L21SP4_RS10255 570cacc5e3a23176b4c7312c4eedee50 478 Gene3D G3DSA:3.20.20.70 107 160 2.4E-18 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP4_RS10255 570cacc5e3a23176b4c7312c4eedee50 478 Gene3D G3DSA:3.20.20.70 198 343 2.4E-18 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP4_RS10255 570cacc5e3a23176b4c7312c4eedee50 478 Gene3D G3DSA:3.20.20.70 8 39 2.4E-18 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP4_RS10255 570cacc5e3a23176b4c7312c4eedee50 478 PANTHER PTHR32332 98 175 5.8E-108 T 22-04-2016 L21SP4_RS10255 570cacc5e3a23176b4c7312c4eedee50 478 PANTHER PTHR32332 397 452 5.8E-108 T 22-04-2016 L21SP4_RS10255 570cacc5e3a23176b4c7312c4eedee50 478 PANTHER PTHR32332 216 361 5.8E-108 T 22-04-2016 L21SP4_RS10255 570cacc5e3a23176b4c7312c4eedee50 478 PANTHER PTHR32332 6 41 5.8E-108 T 22-04-2016 L21SP4_RS10255 570cacc5e3a23176b4c7312c4eedee50 478 SUPERFAMILY SSF51412 141 346 2.01E-13 T 22-04-2016 L21SP4_RS10255 570cacc5e3a23176b4c7312c4eedee50 478 SUPERFAMILY SSF51412 8 65 2.01E-13 T 22-04-2016 L21SP4_RS10255 570cacc5e3a23176b4c7312c4eedee50 478 Pfam PF03060 Nitronate monooxygenase 219 338 1.1E-8 T 22-04-2016 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 L21SP4_RS10255 570cacc5e3a23176b4c7312c4eedee50 478 PANTHER PTHR32332:SF24 98 175 5.8E-108 T 22-04-2016 L21SP4_RS10255 570cacc5e3a23176b4c7312c4eedee50 478 PANTHER PTHR32332:SF24 397 452 5.8E-108 T 22-04-2016 L21SP4_RS10255 570cacc5e3a23176b4c7312c4eedee50 478 PANTHER PTHR32332:SF24 216 361 5.8E-108 T 22-04-2016 L21SP4_RS10255 570cacc5e3a23176b4c7312c4eedee50 478 PANTHER PTHR32332:SF24 6 41 5.8E-108 T 22-04-2016 L21SP4_RS00525 8049377a2a88ee5fdcc3babe7ec5533a 114 PANTHER PTHR15680 2 114 2.6E-42 T 22-04-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS00525 8049377a2a88ee5fdcc3babe7ec5533a 114 Pfam PF01245 Ribosomal protein L19 2 113 2.0E-46 T 22-04-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS00525 8049377a2a88ee5fdcc3babe7ec5533a 114 PRINTS PR00061 Ribosomal protein L19 signature 34 63 1.5E-32 T 22-04-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS00525 8049377a2a88ee5fdcc3babe7ec5533a 114 PRINTS PR00061 Ribosomal protein L19 signature 4 33 1.5E-32 T 22-04-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS00525 8049377a2a88ee5fdcc3babe7ec5533a 114 PRINTS PR00061 Ribosomal protein L19 signature 88 113 1.5E-32 T 22-04-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS00525 8049377a2a88ee5fdcc3babe7ec5533a 114 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 1 114 30.999 T 22-04-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS00525 8049377a2a88ee5fdcc3babe7ec5533a 114 SUPERFAMILY SSF50104 1 113 3.81E-42 T 22-04-2016 IPR008991 Translation protein SH3-like domain L21SP4_RS00525 8049377a2a88ee5fdcc3babe7ec5533a 114 ProSitePatterns PS01015 Ribosomal protein L19 signature. 86 101 - T 22-04-2016 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS00525 8049377a2a88ee5fdcc3babe7ec5533a 114 PIRSF PIRSF002191 1 114 8.5E-47 T 22-04-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS00525 8049377a2a88ee5fdcc3babe7ec5533a 114 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 1 113 5.4E-46 T 22-04-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS04225 2cff491139b4e97d1851ccb1d27d3ffd 170 TIGRFAM TIGR00077 lspA: signal peptidase II 16 156 1.9E-28 T 22-04-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 L21SP4_RS04225 2cff491139b4e97d1851ccb1d27d3ffd 170 Pfam PF01252 Signal peptidase (SPase) II 16 152 9.9E-30 T 22-04-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 L21SP4_RS04225 2cff491139b4e97d1851ccb1d27d3ffd 170 PANTHER PTHR33695:SF1 16 170 3.9E-42 T 22-04-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 L21SP4_RS04225 2cff491139b4e97d1851ccb1d27d3ffd 170 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 5 158 15.02 T 22-04-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 L21SP4_RS04225 2cff491139b4e97d1851ccb1d27d3ffd 170 PANTHER PTHR33695 16 170 3.9E-42 T 22-04-2016 L21SP4_RS04225 2cff491139b4e97d1851ccb1d27d3ffd 170 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 133 149 1.7E-13 T 22-04-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 L21SP4_RS04225 2cff491139b4e97d1851ccb1d27d3ffd 170 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 96 111 1.7E-13 T 22-04-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 L21SP4_RS04225 2cff491139b4e97d1851ccb1d27d3ffd 170 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 52 60 1.7E-13 T 22-04-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 L21SP4_RS02210 0f51057262c73891f1991d54a5e4696b 310 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 2 141 1.7E-43 T 22-04-2016 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 L21SP4_RS02210 0f51057262c73891f1991d54a5e4696b 310 PANTHER PTHR11405 1 306 1.5E-133 T 22-04-2016 L21SP4_RS02210 0f51057262c73891f1991d54a5e4696b 310 PRINTS PR00102 Ornithine carbamoyltransferase signature 77 90 1.2E-21 T 22-04-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 L21SP4_RS02210 0f51057262c73891f1991d54a5e4696b 310 PRINTS PR00102 Ornithine carbamoyltransferase signature 117 131 1.2E-21 T 22-04-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 L21SP4_RS02210 0f51057262c73891f1991d54a5e4696b 310 PRINTS PR00102 Ornithine carbamoyltransferase signature 286 297 1.2E-21 T 22-04-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 L21SP4_RS02210 0f51057262c73891f1991d54a5e4696b 310 PRINTS PR00102 Ornithine carbamoyltransferase signature 43 57 1.2E-21 T 22-04-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 L21SP4_RS02210 0f51057262c73891f1991d54a5e4696b 310 PRINTS PR00102 Ornithine carbamoyltransferase signature 223 233 1.2E-21 T 22-04-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 L21SP4_RS02210 0f51057262c73891f1991d54a5e4696b 310 PANTHER PTHR11405:SF1 1 306 1.5E-133 T 22-04-2016 L21SP4_RS02210 0f51057262c73891f1991d54a5e4696b 310 Gene3D G3DSA:3.40.50.1370 139 294 7.0E-60 T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 L21SP4_RS02210 0f51057262c73891f1991d54a5e4696b 310 Gene3D G3DSA:3.40.50.1370 1 138 6.5E-48 T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 L21SP4_RS02210 0f51057262c73891f1991d54a5e4696b 310 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 272 295 4.6E-25 T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 L21SP4_RS02210 0f51057262c73891f1991d54a5e4696b 310 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 260 269 4.6E-25 T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 L21SP4_RS02210 0f51057262c73891f1991d54a5e4696b 310 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 45 64 4.6E-25 T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 L21SP4_RS02210 0f51057262c73891f1991d54a5e4696b 310 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 128 139 4.6E-25 T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 L21SP4_RS02210 0f51057262c73891f1991d54a5e4696b 310 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 2 305 6.3E-108 T 22-04-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 L21SP4_RS02210 0f51057262c73891f1991d54a5e4696b 310 SUPERFAMILY SSF53671 1 308 5.24E-94 T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 L21SP4_RS02210 0f51057262c73891f1991d54a5e4696b 310 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 147 305 2.5E-53 T 22-04-2016 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 L21SP4_RS07095 914ddb01bbb25efc22cb71ee4ba4efea 465 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 16 316 8.3E-112 T 22-04-2016 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 L21SP4_RS07095 914ddb01bbb25efc22cb71ee4ba4efea 465 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 3 464 1.8E-147 T 22-04-2016 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16|Reactome: REACT_71 L21SP4_RS07095 914ddb01bbb25efc22cb71ee4ba4efea 465 PANTHER PTHR10890 1 459 2.2E-198 T 22-04-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 L21SP4_RS07095 914ddb01bbb25efc22cb71ee4ba4efea 465 Gene3D G3DSA:1.20.120.640 313 407 2.3E-19 T 22-04-2016 L21SP4_RS07095 914ddb01bbb25efc22cb71ee4ba4efea 465 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 26 37 1.9E-26 T 22-04-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 L21SP4_RS07095 914ddb01bbb25efc22cb71ee4ba4efea 465 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 62 71 1.9E-26 T 22-04-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 L21SP4_RS07095 914ddb01bbb25efc22cb71ee4ba4efea 465 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 226 247 1.9E-26 T 22-04-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 L21SP4_RS07095 914ddb01bbb25efc22cb71ee4ba4efea 465 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 195 213 1.9E-26 T 22-04-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 L21SP4_RS07095 914ddb01bbb25efc22cb71ee4ba4efea 465 SUPERFAMILY SSF52374 3 315 7.24E-86 T 22-04-2016 L21SP4_RS07095 914ddb01bbb25efc22cb71ee4ba4efea 465 Pfam PF09190 DALR domain 353 408 2.0E-9 T 22-04-2016 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 L21SP4_RS07095 914ddb01bbb25efc22cb71ee4ba4efea 465 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 3 465 36.382 T 22-04-2016 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16|Reactome: REACT_71 L21SP4_RS07095 914ddb01bbb25efc22cb71ee4ba4efea 465 Gene3D G3DSA:3.40.50.620 20 310 1.4E-97 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP4_RS07095 914ddb01bbb25efc22cb71ee4ba4efea 465 SMART SM00840 353 409 2.0E-6 T 22-04-2016 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 L21SP4_RS07095 914ddb01bbb25efc22cb71ee4ba4efea 465 SUPERFAMILY SSF47323 329 463 3.66E-29 T 22-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 L21SP4_RS02885 18c5c456eb390c06ef10f4368d565a43 126 ProSitePatterns PS00626 Regulator of chromosome condensation (RCC1) signature 2. 1 11 - T 22-04-2016 IPR000408 Regulator of chromosome condensation, RCC1 L21SP4_RS02885 18c5c456eb390c06ef10f4368d565a43 126 Gene3D G3DSA:2.130.10.30 1 40 2.9E-7 T 22-04-2016 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II L21SP4_RS02885 18c5c456eb390c06ef10f4368d565a43 126 Pfam PF13540 Regulator of chromosome condensation (RCC1) repeat 1 24 2.9E-6 T 22-04-2016 L21SP4_RS02885 18c5c456eb390c06ef10f4368d565a43 126 SUPERFAMILY SSF50985 1 90 3.14E-8 T 22-04-2016 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II L21SP4_RS08495 b2a7adfb6bea4144d931c53183f968a5 323 Gene3D G3DSA:3.40.50.10490 9 194 1.0E-47 T 22-04-2016 L21SP4_RS08495 b2a7adfb6bea4144d931c53183f968a5 323 Pfam PF01380 SIS domain 45 170 1.5E-24 T 22-04-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 Reactome: REACT_17015 L21SP4_RS08495 b2a7adfb6bea4144d931c53183f968a5 323 PIRSF PIRSF004692 1 323 5.0E-116 T 22-04-2016 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 L21SP4_RS08495 b2a7adfb6bea4144d931c53183f968a5 323 Pfam PF00571 CBS domain 200 257 6.5E-9 T 22-04-2016 IPR000644 CBS domain L21SP4_RS08495 b2a7adfb6bea4144d931c53183f968a5 323 Pfam PF00571 CBS domain 268 317 1.2E-7 T 22-04-2016 IPR000644 CBS domain L21SP4_RS08495 b2a7adfb6bea4144d931c53183f968a5 323 SUPERFAMILY SSF53697 5 311 1.78E-58 T 22-04-2016 L21SP4_RS08495 b2a7adfb6bea4144d931c53183f968a5 323 Gene3D G3DSA:3.10.580.10 195 317 8.9E-36 T 22-04-2016 L21SP4_RS08495 b2a7adfb6bea4144d931c53183f968a5 323 SMART SM00116 274 322 0.065 T 22-04-2016 IPR000644 CBS domain L21SP4_RS08495 b2a7adfb6bea4144d931c53183f968a5 323 SMART SM00116 209 257 1.4E-5 T 22-04-2016 IPR000644 CBS domain L21SP4_RS08495 b2a7adfb6bea4144d931c53183f968a5 323 TIGRFAM TIGR00393 kpsF: sugar isomerase, KpsF/GutQ family 44 312 6.4E-96 T 22-04-2016 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 L21SP4_RS08495 b2a7adfb6bea4144d931c53183f968a5 323 PANTHER PTHR38418:SF1 2 204 1.2E-40 T 22-04-2016 L21SP4_RS08495 b2a7adfb6bea4144d931c53183f968a5 323 PANTHER PTHR38418 2 204 1.2E-40 T 22-04-2016 L21SP4_RS07635 1760655ec25ee553353e378466069323 316 Pfam PF01145 SPFH domain / Band 7 family 28 215 2.5E-22 T 22-04-2016 IPR001107 Band 7 domain L21SP4_RS07635 1760655ec25ee553353e378466069323 316 SMART SM00244 23 198 4.1E-4 T 22-04-2016 IPR001107 Band 7 domain L21SP4_RS07635 1760655ec25ee553353e378466069323 316 PANTHER PTHR10264 5 263 2.2E-39 T 22-04-2016 IPR001972 Stomatin family GO:0016020 L21SP4_RS07635 1760655ec25ee553353e378466069323 316 PIRSF PIRSF005651 1 305 5.3E-61 T 22-04-2016 IPR010200 HflC GO:0016021|GO:0052547 L21SP4_RS07635 1760655ec25ee553353e378466069323 316 PANTHER PTHR10264:SF80 5 263 2.2E-39 T 22-04-2016 L21SP4_RS07635 1760655ec25ee553353e378466069323 316 SUPERFAMILY SSF117892 63 204 6.93E-17 T 22-04-2016 IPR001107 Band 7 domain L21SP4_RS04875 4c96e55ab46845af2e415ef175d5ee84 431 Gene3D G3DSA:1.25.40.10 170 270 3.6E-16 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS04875 4c96e55ab46845af2e415ef175d5ee84 431 PANTHER PTHR23083 151 338 9.3E-22 T 22-04-2016 L21SP4_RS04875 4c96e55ab46845af2e415ef175d5ee84 431 SUPERFAMILY SSF48452 193 350 6.32E-23 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS04875 4c96e55ab46845af2e415ef175d5ee84 431 Pfam PF14559 Tetratricopeptide repeat 266 328 7.6E-8 T 22-04-2016 L21SP4_RS04875 4c96e55ab46845af2e415ef175d5ee84 431 Pfam PF14559 Tetratricopeptide repeat 170 228 9.0E-6 T 22-04-2016 L21SP4_RS04875 4c96e55ab46845af2e415ef175d5ee84 431 SMART SM00028 289 322 1.9E-4 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS04875 4c96e55ab46845af2e415ef175d5ee84 431 SMART SM00028 255 288 0.12 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS04875 4c96e55ab46845af2e415ef175d5ee84 431 Gene3D G3DSA:1.25.40.10 271 349 1.1E-14 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS01425 bef8dfdad8015966a9dbee05f1e9bb53 276 PANTHER PTHR30570 1 274 3.7E-68 T 22-04-2016 L21SP4_RS01425 bef8dfdad8015966a9dbee05f1e9bb53 276 PANTHER PTHR30570:SF1 1 274 3.7E-68 T 22-04-2016 L21SP4_RS01425 bef8dfdad8015966a9dbee05f1e9bb53 276 Gene3D G3DSA:3.40.190.10 108 230 5.3E-41 T 22-04-2016 L21SP4_RS01425 bef8dfdad8015966a9dbee05f1e9bb53 276 Gene3D G3DSA:3.40.190.10 231 274 1.1E-4 T 22-04-2016 L21SP4_RS01425 bef8dfdad8015966a9dbee05f1e9bb53 276 Gene3D G3DSA:3.40.190.10 40 107 1.1E-4 T 22-04-2016 L21SP4_RS01425 bef8dfdad8015966a9dbee05f1e9bb53 276 Pfam PF12849 PBP superfamily domain 24 243 9.4E-37 T 22-04-2016 IPR024370 PBP domain L21SP4_RS01425 bef8dfdad8015966a9dbee05f1e9bb53 276 TIGRFAM TIGR02136 ptsS_2: phosphate binding protein 20 273 1.4E-78 T 22-04-2016 IPR011862 Phosphate binding protein GO:0006810 L21SP4_RS01425 bef8dfdad8015966a9dbee05f1e9bb53 276 SUPERFAMILY SSF53850 28 274 5.03E-72 T 22-04-2016 L21SP4_RS04400 4dc355b0dace71758280244d9fd6c5af 505 SUPERFAMILY SSF51445 55 339 1.72E-30 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily L21SP4_RS04400 4dc355b0dace71758280244d9fd6c5af 505 Gene3D G3DSA:3.20.20.80 54 323 8.3E-34 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP4_RS04400 4dc355b0dace71758280244d9fd6c5af 505 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 93 320 7.4E-17 T 22-04-2016 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 L21SP4_RS06805 0dcd5e24b14c33865d8272ee2a1c567a 490 SUPERFAMILY SSF143447 313 489 1.23E-56 T 22-04-2016 IPR002733 AMMECR1 domain L21SP4_RS06805 0dcd5e24b14c33865d8272ee2a1c567a 490 Gene3D G3DSA:3.30.1490.150 425 482 1.8E-25 T 22-04-2016 L21SP4_RS06805 0dcd5e24b14c33865d8272ee2a1c567a 490 PANTHER PTHR11060:SF0 4 286 3.8E-79 T 22-04-2016 L21SP4_RS06805 0dcd5e24b14c33865d8272ee2a1c567a 490 Gene3D G3DSA:3.30.700.20 311 424 9.4E-36 T 22-04-2016 IPR027485 AMMECR1, N-terminal L21SP4_RS06805 0dcd5e24b14c33865d8272ee2a1c567a 490 Pfam PF01871 AMMECR1 318 485 1.0E-45 T 22-04-2016 IPR002733 AMMECR1 domain L21SP4_RS06805 0dcd5e24b14c33865d8272ee2a1c567a 490 TIGRFAM TIGR04336 AmmeMemoSam_B: AmmeMemoRadiSam system protein B 10 282 1.1E-67 T 22-04-2016 IPR002737 MEMO1 family L21SP4_RS06805 0dcd5e24b14c33865d8272ee2a1c567a 490 TIGRFAM TIGR04335 AmmeMemoSam_A: AmmeMemoRadiSam system protein A 315 486 3.8E-51 T 22-04-2016 IPR027623 AmmeMemoRadiSam system protein A L21SP4_RS06805 0dcd5e24b14c33865d8272ee2a1c567a 490 Hamap MF_00055 MEMO1 family protein . 6 283 46.217 T 22-04-2016 IPR002737 MEMO1 family L21SP4_RS06805 0dcd5e24b14c33865d8272ee2a1c567a 490 Pfam PF01875 Memo-like protein 10 280 3.2E-60 T 22-04-2016 IPR002737 MEMO1 family L21SP4_RS06805 0dcd5e24b14c33865d8272ee2a1c567a 490 TIGRFAM TIGR00296 TIGR00296: uncharacterized protein, PH0010 family 316 489 7.1E-37 T 22-04-2016 IPR023473 AMMECR1 L21SP4_RS06805 0dcd5e24b14c33865d8272ee2a1c567a 490 PANTHER PTHR11060 4 286 3.8E-79 T 22-04-2016 IPR002737 MEMO1 family L21SP4_RS04070 d5493ddb9e4202ae6d691fef0b1692d5 931 Gene3D G3DSA:1.25.40.10 471 505 9.6E-8 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS04070 d5493ddb9e4202ae6d691fef0b1692d5 931 SUPERFAMILY SSF48452 597 637 9.48E-10 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS04070 d5493ddb9e4202ae6d691fef0b1692d5 931 SUPERFAMILY SSF48452 705 816 9.48E-10 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS04070 d5493ddb9e4202ae6d691fef0b1692d5 931 Pfam PF13525 Outer membrane lipoprotein 456 551 5.2E-9 T 22-04-2016 L21SP4_RS04070 d5493ddb9e4202ae6d691fef0b1692d5 931 Gene3D G3DSA:1.25.40.10 804 911 2.3E-12 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS04070 d5493ddb9e4202ae6d691fef0b1692d5 931 Gene3D G3DSA:1.25.40.10 62 80 1.9E-5 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS04070 d5493ddb9e4202ae6d691fef0b1692d5 931 Gene3D G3DSA:1.25.40.10 128 171 1.9E-5 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS04070 d5493ddb9e4202ae6d691fef0b1692d5 931 SUPERFAMILY SSF48452 788 910 1.61E-13 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS04070 d5493ddb9e4202ae6d691fef0b1692d5 931 PANTHER PTHR23083 383 559 2.0E-27 T 22-04-2016 L21SP4_RS04070 d5493ddb9e4202ae6d691fef0b1692d5 931 PANTHER PTHR23083 600 643 2.0E-27 T 22-04-2016 L21SP4_RS04070 d5493ddb9e4202ae6d691fef0b1692d5 931 PANTHER PTHR23083 726 919 2.0E-27 T 22-04-2016 L21SP4_RS04070 d5493ddb9e4202ae6d691fef0b1692d5 931 PANTHER PTHR23083 44 97 2.0E-27 T 22-04-2016 L21SP4_RS04070 d5493ddb9e4202ae6d691fef0b1692d5 931 Pfam PF13174 Tetratricopeptide repeat 64 91 0.0041 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS04070 d5493ddb9e4202ae6d691fef0b1692d5 931 SMART SM00028 138 171 68.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS04070 d5493ddb9e4202ae6d691fef0b1692d5 931 SMART SM00028 62 95 56.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS04070 d5493ddb9e4202ae6d691fef0b1692d5 931 SMART SM00028 489 522 23.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS04070 d5493ddb9e4202ae6d691fef0b1692d5 931 SMART SM00028 790 822 88.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS04070 d5493ddb9e4202ae6d691fef0b1692d5 931 SMART SM00028 415 448 130.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS04070 d5493ddb9e4202ae6d691fef0b1692d5 931 SMART SM00028 828 861 41.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS04070 d5493ddb9e4202ae6d691fef0b1692d5 931 SMART SM00028 304 337 240.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS04070 d5493ddb9e4202ae6d691fef0b1692d5 931 SMART SM00028 526 559 37.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS04070 d5493ddb9e4202ae6d691fef0b1692d5 931 SMART SM00028 378 411 8.2 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS04070 d5493ddb9e4202ae6d691fef0b1692d5 931 SMART SM00028 866 899 49.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS04070 d5493ddb9e4202ae6d691fef0b1692d5 931 SMART SM00028 600 633 28.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS04070 d5493ddb9e4202ae6d691fef0b1692d5 931 SUPERFAMILY SSF48452 140 171 6.12E-12 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS04070 d5493ddb9e4202ae6d691fef0b1692d5 931 SUPERFAMILY SSF48452 64 100 6.12E-12 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS04070 d5493ddb9e4202ae6d691fef0b1692d5 931 SUPERFAMILY SSF48452 378 485 6.12E-12 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS04070 d5493ddb9e4202ae6d691fef0b1692d5 931 Gene3D G3DSA:1.25.40.10 506 628 1.6E-14 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS04070 d5493ddb9e4202ae6d691fef0b1692d5 931 Gene3D G3DSA:1.25.40.10 81 99 1.7E-11 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS04070 d5493ddb9e4202ae6d691fef0b1692d5 931 Gene3D G3DSA:1.25.40.10 361 470 1.7E-11 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS04070 d5493ddb9e4202ae6d691fef0b1692d5 931 Gene3D G3DSA:1.25.40.10 716 803 1.2E-6 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS04070 d5493ddb9e4202ae6d691fef0b1692d5 931 SUPERFAMILY SSF48452 416 594 2.63E-18 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS04070 d5493ddb9e4202ae6d691fef0b1692d5 931 Pfam PF13432 Tetratricopeptide repeat 795 862 9.8E-4 T 22-04-2016 L21SP4_RS04070 d5493ddb9e4202ae6d691fef0b1692d5 931 Pfam PF13432 Tetratricopeptide repeat 577 628 5.6E-5 T 22-04-2016 L21SP4_RS04070 d5493ddb9e4202ae6d691fef0b1692d5 931 Pfam PF13432 Tetratricopeptide repeat 385 440 2.2E-10 T 22-04-2016 L21SP4_RS07955 e6f311bb030184e86c6504d85a8b4118 216 SUPERFAMILY SSF52833 5 214 2.73E-54 T 22-04-2016 IPR012336 Thioredoxin-like fold L21SP4_RS07955 e6f311bb030184e86c6504d85a8b4118 216 Gene3D G3DSA:3.30.1020.10 160 215 1.3E-15 T 22-04-2016 L21SP4_RS07955 e6f311bb030184e86c6504d85a8b4118 216 Pfam PF00578 AhpC/TSA family 12 139 1.4E-23 T 22-04-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15 L21SP4_RS07955 e6f311bb030184e86c6504d85a8b4118 216 Hamap MF_00401 Peroxiredoxin. 9 214 46.515 T 22-04-2016 IPR022915 Peroxiredoxin, TDXH subfamily GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 L21SP4_RS07955 e6f311bb030184e86c6504d85a8b4118 216 PIRSF PIRSF000239 5 215 1.4E-68 T 22-04-2016 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15 L21SP4_RS07955 e6f311bb030184e86c6504d85a8b4118 216 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 160 197 7.0E-7 T 22-04-2016 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 L21SP4_RS07955 e6f311bb030184e86c6504d85a8b4118 216 PANTHER PTHR10681 5 214 1.3E-56 T 22-04-2016 L21SP4_RS07955 e6f311bb030184e86c6504d85a8b4118 216 Gene3D G3DSA:3.40.30.10 11 159 1.2E-47 T 22-04-2016 IPR012336 Thioredoxin-like fold L21SP4_RS07050 e022d93fa74000965effbc309f07a094 259 Pfam PF03725 3' exoribonuclease family, domain 2 177 243 1.1E-9 T 22-04-2016 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: REACT_21257 L21SP4_RS07050 e022d93fa74000965effbc309f07a094 259 Hamap MF_00564 Ribonuclease PH [rph]. 18 256 44.532 T 22-04-2016 IPR002381 Ribonuclease phosphorolytic, bacterial-type GO:0000049|GO:0004549|GO:0008033 L21SP4_RS07050 e022d93fa74000965effbc309f07a094 259 PANTHER PTHR11953 5 255 1.1E-78 T 22-04-2016 L21SP4_RS07050 e022d93fa74000965effbc309f07a094 259 SUPERFAMILY SSF54211 17 200 2.13E-43 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold L21SP4_RS07050 e022d93fa74000965effbc309f07a094 259 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 19 255 2.8E-110 T 22-04-2016 IPR002381 Ribonuclease phosphorolytic, bacterial-type GO:0000049|GO:0004549|GO:0008033 L21SP4_RS07050 e022d93fa74000965effbc309f07a094 259 ProSitePatterns PS01277 Ribonuclease PH signature. 135 147 - T 22-04-2016 IPR018336 Ribonuclease PH, conserved site L21SP4_RS07050 e022d93fa74000965effbc309f07a094 259 SUPERFAMILY SSF55666 172 255 1.31E-24 T 22-04-2016 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: REACT_21257 L21SP4_RS07050 e022d93fa74000965effbc309f07a094 259 PANTHER PTHR11953:SF0 5 255 1.1E-78 T 22-04-2016 L21SP4_RS07050 e022d93fa74000965effbc309f07a094 259 Pfam PF01138 3' exoribonuclease family, domain 1 27 158 4.0E-25 T 22-04-2016 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: REACT_21257 L21SP4_RS07050 e022d93fa74000965effbc309f07a094 259 Gene3D G3DSA:3.30.230.70 21 256 7.9E-31 T 22-04-2016 IPR027408 PNPase/RNase PH domain L21SP4_RS11575 eb8dbca58818d78bb60f0a4c3d471a71 532 PANTHER PTHR22935:SF10 272 532 1.8E-43 T 22-04-2016 L21SP4_RS11575 eb8dbca58818d78bb60f0a4c3d471a71 532 SUPERFAMILY SSF51556 69 300 5.35E-68 T 22-04-2016 IPR032466 Metal-dependent hydrolase L21SP4_RS11575 eb8dbca58818d78bb60f0a4c3d471a71 532 SUPERFAMILY SSF51556 334 473 5.35E-68 T 22-04-2016 IPR032466 Metal-dependent hydrolase L21SP4_RS11575 eb8dbca58818d78bb60f0a4c3d471a71 532 Gene3D G3DSA:2.30.40.10 15 73 6.5E-18 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 L21SP4_RS11575 eb8dbca58818d78bb60f0a4c3d471a71 532 Gene3D G3DSA:2.30.40.10 460 528 1.3E-7 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 L21SP4_RS11575 eb8dbca58818d78bb60f0a4c3d471a71 532 Gene3D G3DSA:3.20.20.140 74 292 2.6E-92 T 22-04-2016 L21SP4_RS11575 eb8dbca58818d78bb60f0a4c3d471a71 532 Gene3D G3DSA:3.20.20.140 391 459 2.6E-92 T 22-04-2016 L21SP4_RS11575 eb8dbca58818d78bb60f0a4c3d471a71 532 PANTHER PTHR22935 272 532 1.8E-43 T 22-04-2016 L21SP4_RS11575 eb8dbca58818d78bb60f0a4c3d471a71 532 Pfam PF07969 Amidohydrolase family 59 516 2.2E-26 T 22-04-2016 IPR013108 Amidohydrolase 3 L21SP4_RS11575 eb8dbca58818d78bb60f0a4c3d471a71 532 SUPERFAMILY SSF51338 8 69 2.09E-21 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 L21SP4_RS11575 eb8dbca58818d78bb60f0a4c3d471a71 532 SUPERFAMILY SSF51338 473 515 2.09E-21 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 L21SP4_RS02055 3c82c247e7d72805f6fbece54b2cef00 520 Gene3D G3DSA:3.30.1120.10 424 434 4.8E-13 T 22-04-2016 L21SP4_RS02055 3c82c247e7d72805f6fbece54b2cef00 520 Gene3D G3DSA:3.30.1120.10 471 509 4.8E-13 T 22-04-2016 L21SP4_RS02055 3c82c247e7d72805f6fbece54b2cef00 520 PANTHER PTHR10342 3 511 3.2E-130 T 22-04-2016 L21SP4_RS02055 3c82c247e7d72805f6fbece54b2cef00 520 ProSitePatterns PS00149 Sulfatases signature 2. 141 151 - T 22-04-2016 IPR024607 Sulfatase, conserved site L21SP4_RS02055 3c82c247e7d72805f6fbece54b2cef00 520 SUPERFAMILY SSF53649 472 509 2.76E-108 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS02055 3c82c247e7d72805f6fbece54b2cef00 520 SUPERFAMILY SSF53649 37 435 2.76E-108 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS02055 3c82c247e7d72805f6fbece54b2cef00 520 Pfam PF00884 Sulfatase 38 376 3.4E-67 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS02055 3c82c247e7d72805f6fbece54b2cef00 520 PANTHER PTHR10342:SF199 3 511 3.2E-130 T 22-04-2016 L21SP4_RS02055 3c82c247e7d72805f6fbece54b2cef00 520 Gene3D G3DSA:3.40.720.10 37 423 4.7E-98 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS07660 bd06de5ee70437605bf052bfbe3e0865 382 Pfam PF13635 Domain of unknown function (DUF4143) 200 326 6.1E-18 T 22-04-2016 IPR025420 Domain of unknown function DUF4143 L21SP4_RS07660 bd06de5ee70437605bf052bfbe3e0865 382 PANTHER PTHR33295 14 382 4.8E-103 T 22-04-2016 L21SP4_RS07660 bd06de5ee70437605bf052bfbe3e0865 382 PANTHER PTHR33295:SF4 14 382 4.8E-103 T 22-04-2016 L21SP4_RS07660 bd06de5ee70437605bf052bfbe3e0865 382 Gene3D G3DSA:3.40.50.300 8 96 9.3E-4 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS07660 bd06de5ee70437605bf052bfbe3e0865 382 Pfam PF13173 AAA domain 16 132 3.8E-17 T 22-04-2016 L21SP4_RS07660 bd06de5ee70437605bf052bfbe3e0865 382 SUPERFAMILY SSF52540 13 132 3.05E-10 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS07165 ac2f9195ca42d648a4ea3dcfb7133f41 281 SUPERFAMILY SSF52768 19 276 7.38E-60 T 22-04-2016 L21SP4_RS07165 ac2f9195ca42d648a4ea3dcfb7133f41 281 ProSitePatterns PS01053 Arginase family signature. 205 226 - T 22-04-2016 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 Reactome: REACT_13 L21SP4_RS07165 ac2f9195ca42d648a4ea3dcfb7133f41 281 PANTHER PTHR11358 25 277 2.1E-68 T 22-04-2016 IPR006035 Ureohydrolase GO:0046872 Reactome: REACT_13 L21SP4_RS07165 ac2f9195ca42d648a4ea3dcfb7133f41 281 Gene3D G3DSA:3.40.800.10 5 278 2.5E-59 T 22-04-2016 IPR023696 Ureohydrolase domain L21SP4_RS07165 ac2f9195ca42d648a4ea3dcfb7133f41 281 TIGRFAM TIGR01230 agmatinase: agmatinase 23 275 1.7E-53 T 22-04-2016 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|UniPathway: UPA00534 L21SP4_RS07165 ac2f9195ca42d648a4ea3dcfb7133f41 281 Pfam PF00491 Arginase family 24 273 2.1E-56 T 22-04-2016 IPR006035 Ureohydrolase GO:0046872 Reactome: REACT_13 L21SP4_RS07165 ac2f9195ca42d648a4ea3dcfb7133f41 281 PIRSF PIRSF036979 3 281 1.6E-50 T 22-04-2016 IPR006035 Ureohydrolase GO:0046872 Reactome: REACT_13 L21SP4_RS07165 ac2f9195ca42d648a4ea3dcfb7133f41 281 PANTHER PTHR11358:SF34 25 277 2.1E-68 T 22-04-2016 L21SP4_RS02575 cbdd1268ca22755d7ee91fc5febaf133 157 PANTHER PTHR15160 22 135 7.6E-22 T 22-04-2016 L21SP4_RS02575 cbdd1268ca22755d7ee91fc5febaf133 157 SUPERFAMILY SSF103256 14 136 2.09E-31 T 22-04-2016 IPR003729 Bifunctional nuclease domain GO:0004518 L21SP4_RS02575 cbdd1268ca22755d7ee91fc5febaf133 157 Pfam PF02577 Bifunctional nuclease 22 136 4.1E-33 T 22-04-2016 IPR003729 Bifunctional nuclease domain GO:0004518 L21SP4_RS02575 cbdd1268ca22755d7ee91fc5febaf133 157 PANTHER PTHR15160:SF1 22 135 7.6E-22 T 22-04-2016 L21SP4_RS02535 9cc3bba34a45c96d588d92d80bb5533f 103 SUPERFAMILY SSF82607 4 96 1.14E-28 T 22-04-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family L21SP4_RS02535 9cc3bba34a45c96d588d92d80bb5533f 103 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 2 90 9.8E-23 T 22-04-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family L21SP4_RS02535 9cc3bba34a45c96d588d92d80bb5533f 103 PANTHER PTHR33449:SF1 1 98 8.2E-36 T 22-04-2016 L21SP4_RS02535 9cc3bba34a45c96d588d92d80bb5533f 103 PIRSF PIRSF004555 1 103 9.1E-34 T 22-04-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family L21SP4_RS02535 9cc3bba34a45c96d588d92d80bb5533f 103 Gene3D G3DSA:3.30.1310.10 1 99 1.9E-34 T 22-04-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family L21SP4_RS02535 9cc3bba34a45c96d588d92d80bb5533f 103 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 2 96 21.147 T 22-04-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family L21SP4_RS02535 9cc3bba34a45c96d588d92d80bb5533f 103 Pfam PF02575 YbaB/EbfC DNA-binding family 8 97 1.6E-31 T 22-04-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family L21SP4_RS02535 9cc3bba34a45c96d588d92d80bb5533f 103 PANTHER PTHR33449 1 98 8.2E-36 T 22-04-2016 L21SP4_RS00125 2315b2dbb7af76d717747335cc79fbc4 368 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 7 356 6.7E-143 T 22-04-2016 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 L21SP4_RS00125 2315b2dbb7af76d717747335cc79fbc4 368 Pfam PF00472 RF-1 domain 213 322 7.4E-44 T 22-04-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 L21SP4_RS00125 2315b2dbb7af76d717747335cc79fbc4 368 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 3 358 37.607 T 22-04-2016 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 L21SP4_RS00125 2315b2dbb7af76d717747335cc79fbc4 368 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 229 245 - T 22-04-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 L21SP4_RS00125 2315b2dbb7af76d717747335cc79fbc4 368 PANTHER PTHR11075:SF9 1 357 5.2E-162 T 22-04-2016 L21SP4_RS00125 2315b2dbb7af76d717747335cc79fbc4 368 Gene3D G3DSA:1.20.58.410 7 95 3.7E-10 T 22-04-2016 L21SP4_RS00125 2315b2dbb7af76d717747335cc79fbc4 368 SMART SM00937 65 180 5.9E-47 T 22-04-2016 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 L21SP4_RS00125 2315b2dbb7af76d717747335cc79fbc4 368 Pfam PF03462 PCRF domain 14 205 4.5E-62 T 22-04-2016 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 L21SP4_RS00125 2315b2dbb7af76d717747335cc79fbc4 368 Gene3D G3DSA:3.30.160.20 212 289 2.8E-36 T 22-04-2016 IPR014720 Double-stranded RNA-binding domain L21SP4_RS00125 2315b2dbb7af76d717747335cc79fbc4 368 PANTHER PTHR11075 1 357 5.2E-162 T 22-04-2016 L21SP4_RS00125 2315b2dbb7af76d717747335cc79fbc4 368 SUPERFAMILY SSF75620 10 354 2.35E-127 T 22-04-2016 L21SP4_RS05165 80e5d17b5292a5a8773b32f0f606b77b 66 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 6 62 9.7E-21 T 22-04-2016 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 L21SP4_RS05165 80e5d17b5292a5a8773b32f0f606b77b 66 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 19 48 4.0E-5 T 22-04-2016 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 L21SP4_RS05165 80e5d17b5292a5a8773b32f0f606b77b 66 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 5 61 17.149 T 22-04-2016 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 L21SP4_RS05165 80e5d17b5292a5a8773b32f0f606b77b 66 PANTHER PTHR21109 6 62 3.7E-14 T 22-04-2016 L21SP4_RS05165 80e5d17b5292a5a8773b32f0f606b77b 66 PRINTS PR00976 Ribosomal protein S21 family signature 17 26 1.5E-8 T 22-04-2016 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 L21SP4_RS05165 80e5d17b5292a5a8773b32f0f606b77b 66 PRINTS PR00976 Ribosomal protein S21 family signature 9 17 1.5E-8 T 22-04-2016 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 L21SP4_RS05165 80e5d17b5292a5a8773b32f0f606b77b 66 PRINTS PR00976 Ribosomal protein S21 family signature 41 51 1.5E-8 T 22-04-2016 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 L21SP4_RS05165 80e5d17b5292a5a8773b32f0f606b77b 66 PRINTS PR00976 Ribosomal protein S21 family signature 29 39 1.5E-8 T 22-04-2016 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 L21SP4_RS05165 80e5d17b5292a5a8773b32f0f606b77b 66 Pfam PF01165 Ribosomal protein S21 7 59 1.4E-18 T 22-04-2016 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 L21SP4_RS05165 80e5d17b5292a5a8773b32f0f606b77b 66 ProSitePatterns PS01181 Ribosomal protein S21 signature. 17 29 - T 22-04-2016 IPR018278 Ribosomal protein S21, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS03055 36b0af55f6dc6ecf02335fc88678b238 222 Gene3D G3DSA:3.40.50.2300 10 124 6.5E-26 T 22-04-2016 L21SP4_RS03055 36b0af55f6dc6ecf02335fc88678b238 222 Pfam PF00072 Response regulator receiver domain 10 120 3.0E-18 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 L21SP4_RS03055 36b0af55f6dc6ecf02335fc88678b238 222 SUPERFAMILY SSF52172 9 126 1.42E-25 T 22-04-2016 IPR011006 CheY-like superfamily L21SP4_RS03055 36b0af55f6dc6ecf02335fc88678b238 222 SMART SM00448 8 119 9.5E-17 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 L21SP4_RS03055 36b0af55f6dc6ecf02335fc88678b238 222 PANTHER PTHR32071 10 122 7.1E-20 T 22-04-2016 L21SP4_RS03055 36b0af55f6dc6ecf02335fc88678b238 222 PANTHER PTHR32071:SF16 10 122 7.1E-20 T 22-04-2016 L21SP4_RS08920 cc6cc66227eb52caa755fca49f60f048 265 Gene3D G3DSA:3.40.50.880 3 260 4.7E-19 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like L21SP4_RS08920 cc6cc66227eb52caa755fca49f60f048 265 PIRSF PIRSF001586 1 265 7.7E-67 T 22-04-2016 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 L21SP4_RS08920 cc6cc66227eb52caa755fca49f60f048 265 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 3 260 1.1E-80 T 22-04-2016 L21SP4_RS08920 cc6cc66227eb52caa755fca49f60f048 265 PANTHER PTHR10099 3 265 9.5E-80 T 22-04-2016 L21SP4_RS08920 cc6cc66227eb52caa755fca49f60f048 265 SMART SM01211 2 262 2.2E-101 T 22-04-2016 L21SP4_RS08920 cc6cc66227eb52caa755fca49f60f048 265 SUPERFAMILY SSF52317 2 261 1.13E-70 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like L21SP4_RS05275 76258cee6195f849a1518c645dff7cdf 761 PANTHER PTHR31998:SF0 178 540 0.0 T 22-04-2016 L21SP4_RS05275 76258cee6195f849a1518c645dff7cdf 761 PANTHER PTHR31998:SF0 558 753 0.0 T 22-04-2016 L21SP4_RS05275 76258cee6195f849a1518c645dff7cdf 761 PANTHER PTHR31998:SF0 12 159 0.0 T 22-04-2016 L21SP4_RS05275 76258cee6195f849a1518c645dff7cdf 761 Pfam PF03030 Inorganic H+ pyrophosphatase 19 738 1.0E-264 T 22-04-2016 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1 L21SP4_RS05275 76258cee6195f849a1518c645dff7cdf 761 TIGRFAM TIGR01104 V_PPase: V-type H(+)-translocating pyrophosphatase 13 744 7.6E-220 T 22-04-2016 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1 L21SP4_RS05275 76258cee6195f849a1518c645dff7cdf 761 Hamap MF_01129 Putative K(+)-stimulated pyrophosphate-energized sodium pump [hppA]. 8 743 23.883 T 22-04-2016 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1 L21SP4_RS05275 76258cee6195f849a1518c645dff7cdf 761 PIRSF PIRSF001265 6 752 3.7E-254 T 22-04-2016 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1 L21SP4_RS05275 76258cee6195f849a1518c645dff7cdf 761 PANTHER PTHR31998 178 540 0.0 T 22-04-2016 L21SP4_RS05275 76258cee6195f849a1518c645dff7cdf 761 PANTHER PTHR31998 558 753 0.0 T 22-04-2016 L21SP4_RS05275 76258cee6195f849a1518c645dff7cdf 761 PANTHER PTHR31998 12 159 0.0 T 22-04-2016 L21SP4_RS01285 4b60583370a475d083cf2ddf056e0f60 569 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 47 144 2.0E-20 T 22-04-2016 IPR007831 General secretory system II, protein E, N-terminal GO:0005524|GO:0006810 L21SP4_RS01285 4b60583370a475d083cf2ddf056e0f60 569 SUPERFAMILY SSF160246 8 142 2.88E-32 T 22-04-2016 L21SP4_RS01285 4b60583370a475d083cf2ddf056e0f60 569 PANTHER PTHR30258:SF2 8 564 1.5E-213 T 22-04-2016 L21SP4_RS01285 4b60583370a475d083cf2ddf056e0f60 569 SMART SM00382 317 439 1.1E-4 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS01285 4b60583370a475d083cf2ddf056e0f60 569 PANTHER PTHR30258 8 564 1.5E-213 T 22-04-2016 L21SP4_RS01285 4b60583370a475d083cf2ddf056e0f60 569 SUPERFAMILY SSF52540 179 564 1.48E-100 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS01285 4b60583370a475d083cf2ddf056e0f60 569 Gene3D G3DSA:3.30.450.90 165 289 1.6E-48 T 22-04-2016 L21SP4_RS01285 4b60583370a475d083cf2ddf056e0f60 569 Gene3D G3DSA:3.40.50.300 296 564 5.0E-100 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS01285 4b60583370a475d083cf2ddf056e0f60 569 Pfam PF00437 Type II/IV secretion system protein 190 456 4.3E-76 T 22-04-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 L21SP4_RS01285 4b60583370a475d083cf2ddf056e0f60 569 TIGRFAM TIGR02533 type_II_gspE: type II secretion system protein E 83 564 1.3E-191 T 22-04-2016 IPR013369 Type II secretion system GspE GO:0005524|GO:0008565|GO:0015627|GO:0015628 L21SP4_RS11360 61b3d063f8a015978b35150f4a8e4d60 273 Gene3D G3DSA:3.40.190.80 169 268 1.5E-43 T 22-04-2016 L21SP4_RS11360 61b3d063f8a015978b35150f4a8e4d60 273 PANTHER PTHR20854 1 270 5.2E-72 T 22-04-2016 IPR000760 Inositol monophosphatase GO:0046854 L21SP4_RS11360 61b3d063f8a015978b35150f4a8e4d60 273 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 228 242 - T 22-04-2016 IPR020550 Inositol monophosphatase, conserved site GO:0046854 L21SP4_RS11360 61b3d063f8a015978b35150f4a8e4d60 273 PANTHER PTHR20854:SF5 1 270 5.2E-72 T 22-04-2016 L21SP4_RS11360 61b3d063f8a015978b35150f4a8e4d60 273 SUPERFAMILY SSF56655 4 269 4.19E-66 T 22-04-2016 L21SP4_RS11360 61b3d063f8a015978b35150f4a8e4d60 273 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 81 94 - T 22-04-2016 IPR020583 Inositol monophosphatase, metal-binding site L21SP4_RS11360 61b3d063f8a015978b35150f4a8e4d60 273 Pfam PF00459 Inositol monophosphatase family 8 252 8.8E-47 T 22-04-2016 IPR000760 Inositol monophosphatase GO:0046854 L21SP4_RS11360 61b3d063f8a015978b35150f4a8e4d60 273 Gene3D G3DSA:3.30.540.10 5 141 8.7E-41 T 22-04-2016 L21SP4_RS11360 61b3d063f8a015978b35150f4a8e4d60 273 TIGRFAM TIGR01331 bisphos_cysQ: 3'(2'),5'-bisphosphate nucleotidase 9 267 3.9E-86 T 22-04-2016 IPR006240 3(2),5 -bisphosphate nucleotidase, bacterial GO:0000287|GO:0016020 KEGG: 00920+3.1.3.7 L21SP4_RS11360 61b3d063f8a015978b35150f4a8e4d60 273 PRINTS PR00377 Inositol monophosphatase superfamily signature 225 249 3.8E-9 T 22-04-2016 IPR000760 Inositol monophosphatase GO:0046854 L21SP4_RS11360 61b3d063f8a015978b35150f4a8e4d60 273 PRINTS PR00377 Inositol monophosphatase superfamily signature 37 57 3.8E-9 T 22-04-2016 IPR000760 Inositol monophosphatase GO:0046854 L21SP4_RS11360 61b3d063f8a015978b35150f4a8e4d60 273 PRINTS PR00377 Inositol monophosphatase superfamily signature 81 97 3.8E-9 T 22-04-2016 IPR000760 Inositol monophosphatase GO:0046854 L21SP4_RS10915 b202e202c7d1ffeeb39cc807ec5e4327 569 PANTHER PTHR32432 1 386 3.3E-63 T 22-04-2016 L21SP4_RS10915 b202e202c7d1ffeeb39cc807ec5e4327 569 SUPERFAMILY SSF53067 58 165 3.5E-12 T 22-04-2016 L21SP4_RS10915 b202e202c7d1ffeeb39cc807ec5e4327 569 TIGRFAM TIGR01175 pilM: type IV pilus assembly protein PilM 7 348 1.3E-61 T 22-04-2016 IPR005883 Type IV pilus assembly protein PilM L21SP4_RS10915 b202e202c7d1ffeeb39cc807ec5e4327 569 Pfam PF11104 Type IV pilus assembly protein PilM; 10 347 4.6E-48 T 22-04-2016 IPR005883 Type IV pilus assembly protein PilM L21SP4_RS10915 b202e202c7d1ffeeb39cc807ec5e4327 569 PANTHER PTHR32432:SF3 1 386 3.3E-63 T 22-04-2016 L21SP4_RS10915 b202e202c7d1ffeeb39cc807ec5e4327 569 Gene3D G3DSA:3.30.420.40 182 311 2.6E-20 T 22-04-2016 L21SP4_RS10915 b202e202c7d1ffeeb39cc807ec5e4327 569 SMART SM00842 7 169 0.0014 T 22-04-2016 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 L21SP4_RS10915 b202e202c7d1ffeeb39cc807ec5e4327 569 SUPERFAMILY SSF53067 179 313 3.18E-16 T 22-04-2016 L21SP4_RS08430 f49d8ee82b521cf200190e14dbee9f48 1383 Pfam PF04997 RNA polymerase Rpb1, domain 1 19 344 8.6E-87 T 22-04-2016 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 L21SP4_RS08430 f49d8ee82b521cf200190e14dbee9f48 1383 Pfam PF04983 RNA polymerase Rpb1, domain 3 491 654 2.9E-21 T 22-04-2016 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 L21SP4_RS08430 f49d8ee82b521cf200190e14dbee9f48 1383 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 16 1363 10.222 T 22-04-2016 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 L21SP4_RS08430 f49d8ee82b521cf200190e14dbee9f48 1383 SMART SM00663 237 516 1.2E-167 T 22-04-2016 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 L21SP4_RS08430 f49d8ee82b521cf200190e14dbee9f48 1383 Pfam PF00623 RNA polymerase Rpb1, domain 2 392 487 3.6E-26 T 22-04-2016 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 L21SP4_RS08430 f49d8ee82b521cf200190e14dbee9f48 1383 Pfam PF00623 RNA polymerase Rpb1, domain 2 346 399 2.2E-9 T 22-04-2016 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 L21SP4_RS08430 f49d8ee82b521cf200190e14dbee9f48 1383 Pfam PF05000 RNA polymerase Rpb1, domain 4 683 756 1.8E-16 T 22-04-2016 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 L21SP4_RS08430 f49d8ee82b521cf200190e14dbee9f48 1383 PANTHER PTHR19376:SF32 5 564 0.0 T 22-04-2016 L21SP4_RS08430 f49d8ee82b521cf200190e14dbee9f48 1383 PANTHER PTHR19376:SF32 1290 1351 0.0 T 22-04-2016 L21SP4_RS08430 f49d8ee82b521cf200190e14dbee9f48 1383 PANTHER PTHR19376:SF32 582 962 0.0 T 22-04-2016 L21SP4_RS08430 f49d8ee82b521cf200190e14dbee9f48 1383 PANTHER PTHR19376:SF32 1164 1249 0.0 T 22-04-2016 L21SP4_RS08430 f49d8ee82b521cf200190e14dbee9f48 1383 PANTHER PTHR19376:SF32 987 1144 0.0 T 22-04-2016 L21SP4_RS08430 f49d8ee82b521cf200190e14dbee9f48 1383 PANTHER PTHR19376 5 564 0.0 T 22-04-2016 L21SP4_RS08430 f49d8ee82b521cf200190e14dbee9f48 1383 PANTHER PTHR19376 1290 1351 0.0 T 22-04-2016 L21SP4_RS08430 f49d8ee82b521cf200190e14dbee9f48 1383 PANTHER PTHR19376 582 962 0.0 T 22-04-2016 L21SP4_RS08430 f49d8ee82b521cf200190e14dbee9f48 1383 PANTHER PTHR19376 1164 1249 0.0 T 22-04-2016 L21SP4_RS08430 f49d8ee82b521cf200190e14dbee9f48 1383 Gene3D G3DSA:2.40.50.100 1143 1199 3.8E-9 T 22-04-2016 L21SP4_RS08430 f49d8ee82b521cf200190e14dbee9f48 1383 Gene3D G3DSA:2.40.50.100 1064 1108 8.3E-4 T 22-04-2016 L21SP4_RS08430 f49d8ee82b521cf200190e14dbee9f48 1383 Pfam PF04998 RNA polymerase Rpb1, domain 5 767 1303 2.0E-72 T 22-04-2016 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 L21SP4_RS08430 f49d8ee82b521cf200190e14dbee9f48 1383 PANTHER PTHR19376 987 1144 0.0 T 22-04-2016 L21SP4_RS08430 f49d8ee82b521cf200190e14dbee9f48 1383 Gene3D G3DSA:2.40.40.20 419 491 1.6E-35 T 22-04-2016 L21SP4_RS08430 f49d8ee82b521cf200190e14dbee9f48 1383 Gene3D G3DSA:2.40.40.20 351 378 1.6E-35 T 22-04-2016 L21SP4_RS08430 f49d8ee82b521cf200190e14dbee9f48 1383 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 21 1354 0.0 T 22-04-2016 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 L21SP4_RS08430 f49d8ee82b521cf200190e14dbee9f48 1383 SUPERFAMILY SSF64484 18 945 0.0 T 22-04-2016 L21SP4_RS08430 f49d8ee82b521cf200190e14dbee9f48 1383 SUPERFAMILY SSF64484 1120 1351 0.0 T 22-04-2016 L21SP4_RS08550 54fbf33cb8396ee73597eb31b4b8c3e6 198 SMART SM00363 91 151 3.1E-15 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 L21SP4_RS08550 54fbf33cb8396ee73597eb31b4b8c3e6 198 Pfam PF01479 S4 domain 92 138 1.0E-15 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 L21SP4_RS08550 54fbf33cb8396ee73597eb31b4b8c3e6 198 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 2 198 7.1E-67 T 22-04-2016 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 L21SP4_RS08550 54fbf33cb8396ee73597eb31b4b8c3e6 198 SUPERFAMILY SSF55174 3 198 1.44E-56 T 22-04-2016 L21SP4_RS08550 54fbf33cb8396ee73597eb31b4b8c3e6 198 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 198 30.846 T 22-04-2016 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 L21SP4_RS08550 54fbf33cb8396ee73597eb31b4b8c3e6 198 PANTHER PTHR11831 1 198 4.7E-61 T 22-04-2016 IPR022801 Ribosomal protein S4/S9 L21SP4_RS08550 54fbf33cb8396ee73597eb31b4b8c3e6 198 SMART SM01390 1 90 2.1E-31 T 22-04-2016 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 L21SP4_RS08550 54fbf33cb8396ee73597eb31b4b8c3e6 198 PANTHER PTHR11831:SF4 1 198 4.7E-61 T 22-04-2016 L21SP4_RS08550 54fbf33cb8396ee73597eb31b4b8c3e6 198 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 90 9.9E-22 T 22-04-2016 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 L21SP4_RS08550 54fbf33cb8396ee73597eb31b4b8c3e6 198 Gene3D G3DSA:3.10.290.10 94 185 7.5E-27 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 L21SP4_RS08550 54fbf33cb8396ee73597eb31b4b8c3e6 198 ProSitePatterns PS00632 Ribosomal protein S4 signature. 89 113 - T 22-04-2016 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 L21SP4_RS08550 54fbf33cb8396ee73597eb31b4b8c3e6 198 Gene3D G3DSA:1.10.1050.10 3 93 3.9E-29 T 22-04-2016 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 L21SP4_RS10640 ff8d0d49aacb7cf00af40c704ce82fb5 292 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 92 108 - T 22-04-2016 IPR000092 Polyprenyl synthetase GO:0008299 L21SP4_RS10640 ff8d0d49aacb7cf00af40c704ce82fb5 292 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 223 235 - T 22-04-2016 IPR000092 Polyprenyl synthetase GO:0008299 L21SP4_RS10640 ff8d0d49aacb7cf00af40c704ce82fb5 292 Gene3D G3DSA:1.10.600.10 16 281 2.7E-76 T 22-04-2016 IPR008949 Isoprenoid synthase domain L21SP4_RS10640 ff8d0d49aacb7cf00af40c704ce82fb5 292 SUPERFAMILY SSF48576 16 270 9.66E-71 T 22-04-2016 IPR008949 Isoprenoid synthase domain L21SP4_RS10640 ff8d0d49aacb7cf00af40c704ce82fb5 292 Pfam PF00348 Polyprenyl synthetase 43 242 1.6E-44 T 22-04-2016 IPR000092 Polyprenyl synthetase GO:0008299 L21SP4_RS10640 ff8d0d49aacb7cf00af40c704ce82fb5 292 PANTHER PTHR12001:SF23 15 269 3.0E-79 T 22-04-2016 L21SP4_RS10640 ff8d0d49aacb7cf00af40c704ce82fb5 292 PANTHER PTHR12001 15 269 3.0E-79 T 22-04-2016 IPR017446 Polyprenyl synthetase-related L21SP4_RS05765 209123233f18d79c2c5d2fcfbd0a5e17 757 PANTHER PTHR12815:SF11 5 757 1.2E-143 T 22-04-2016 L21SP4_RS05765 209123233f18d79c2c5d2fcfbd0a5e17 757 PIRSF PIRSF006076 2 757 3.4E-177 T 22-04-2016 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 L21SP4_RS05765 209123233f18d79c2c5d2fcfbd0a5e17 757 Pfam PF07244 Surface antigen variable number repeat 352 424 1.2E-16 T 22-04-2016 IPR010827 Surface antigen variable number GO:0019867 L21SP4_RS05765 209123233f18d79c2c5d2fcfbd0a5e17 757 Pfam PF07244 Surface antigen variable number repeat 100 177 8.2E-8 T 22-04-2016 IPR010827 Surface antigen variable number GO:0019867 L21SP4_RS05765 209123233f18d79c2c5d2fcfbd0a5e17 757 Pfam PF07244 Surface antigen variable number repeat 181 264 3.8E-10 T 22-04-2016 IPR010827 Surface antigen variable number GO:0019867 L21SP4_RS05765 209123233f18d79c2c5d2fcfbd0a5e17 757 TIGRFAM TIGR03303 OM_YaeT: outer membrane protein assembly complex, YaeT protein 27 757 1.1E-157 T 22-04-2016 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 L21SP4_RS05765 209123233f18d79c2c5d2fcfbd0a5e17 757 PANTHER PTHR12815 5 757 1.2E-143 T 22-04-2016 L21SP4_RS05765 209123233f18d79c2c5d2fcfbd0a5e17 757 Pfam PF01103 Surface antigen 461 757 2.6E-61 T 22-04-2016 IPR000184 Bacterial surface antigen (D15) GO:0019867 L21SP4_RS05765 209123233f18d79c2c5d2fcfbd0a5e17 757 Gene3D G3DSA:2.40.160.50 592 757 2.8E-19 T 22-04-2016 L21SP4_RS10665 85e1099ae0307f893758f7163f1348c0 399 Pfam PF00226 DnaJ domain 7 69 4.7E-30 T 22-04-2016 IPR001623 DnaJ domain L21SP4_RS10665 85e1099ae0307f893758f7163f1348c0 399 PANTHER PTHR24078:SF190 1 367 3.3E-138 T 22-04-2016 L21SP4_RS10665 85e1099ae0307f893758f7163f1348c0 399 PRINTS PR00625 DnaJ domain signature 64 83 3.6E-34 T 22-04-2016 IPR001623 DnaJ domain L21SP4_RS10665 85e1099ae0307f893758f7163f1348c0 399 PRINTS PR00625 DnaJ domain signature 44 64 3.6E-34 T 22-04-2016 IPR001623 DnaJ domain L21SP4_RS10665 85e1099ae0307f893758f7163f1348c0 399 PRINTS PR00625 DnaJ domain signature 9 27 3.6E-34 T 22-04-2016 IPR001623 DnaJ domain L21SP4_RS10665 85e1099ae0307f893758f7163f1348c0 399 PRINTS PR00625 DnaJ domain signature 27 42 3.6E-34 T 22-04-2016 IPR001623 DnaJ domain L21SP4_RS10665 85e1099ae0307f893758f7163f1348c0 399 ProSitePatterns PS00636 Nt-dnaJ domain signature. 49 68 - T 22-04-2016 IPR018253 DnaJ domain, conserved site L21SP4_RS10665 85e1099ae0307f893758f7163f1348c0 399 SMART SM00271 6 64 7.5E-36 T 22-04-2016 IPR001623 DnaJ domain L21SP4_RS10665 85e1099ae0307f893758f7163f1348c0 399 SUPERFAMILY SSF49493 233 277 8.11E-16 T 22-04-2016 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 L21SP4_RS10665 85e1099ae0307f893758f7163f1348c0 399 SUPERFAMILY SSF49493 139 172 8.11E-16 T 22-04-2016 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 L21SP4_RS10665 85e1099ae0307f893758f7163f1348c0 399 Gene3D G3DSA:1.10.287.110 4 94 1.5E-37 T 22-04-2016 IPR001623 DnaJ domain L21SP4_RS10665 85e1099ae0307f893758f7163f1348c0 399 SUPERFAMILY SSF46565 4 98 2.62E-36 T 22-04-2016 IPR001623 DnaJ domain L21SP4_RS10665 85e1099ae0307f893758f7163f1348c0 399 Gene3D G3DSA:2.10.230.10 162 229 6.4E-20 T 22-04-2016 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 L21SP4_RS10665 85e1099ae0307f893758f7163f1348c0 399 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 4 395 39.946 T 22-04-2016 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 L21SP4_RS10665 85e1099ae0307f893758f7163f1348c0 399 Pfam PF01556 DnaJ C terminal domain 141 353 3.4E-37 T 22-04-2016 IPR002939 Chaperone DnaJ, C-terminal L21SP4_RS10665 85e1099ae0307f893758f7163f1348c0 399 SUPERFAMILY SSF49493 278 364 1.06E-19 T 22-04-2016 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 L21SP4_RS10665 85e1099ae0307f893758f7163f1348c0 399 PANTHER PTHR24078 1 367 3.3E-138 T 22-04-2016 L21SP4_RS10665 85e1099ae0307f893758f7163f1348c0 399 Gene3D G3DSA:2.60.260.20 230 274 1.6E-17 T 22-04-2016 L21SP4_RS10665 85e1099ae0307f893758f7163f1348c0 399 Gene3D G3DSA:2.60.260.20 123 161 1.6E-17 T 22-04-2016 L21SP4_RS10665 85e1099ae0307f893758f7163f1348c0 399 Gene3D G3DSA:2.60.260.20 276 354 2.6E-18 T 22-04-2016 L21SP4_RS10665 85e1099ae0307f893758f7163f1348c0 399 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 7 368 9.1E-130 T 22-04-2016 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 L21SP4_RS10665 85e1099ae0307f893758f7163f1348c0 399 SUPERFAMILY SSF57938 154 230 6.93E-18 T 22-04-2016 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 L21SP4_RS10665 85e1099ae0307f893758f7163f1348c0 399 Pfam PF00684 DnaJ central domain 167 227 2.1E-10 T 22-04-2016 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 L21SP4_RS05610 cb09dff917b9116401e318227e0ef0d1 424 Pfam PF04165 Protein of unknown function (DUF401) 24 417 2.8E-43 T 22-04-2016 IPR007294 Protein of unknown function DUF401 L21SP4_RS05610 cb09dff917b9116401e318227e0ef0d1 424 PANTHER PTHR39556 2 423 1.4E-62 T 22-04-2016 L21SP4_RS11555 8739702044ad2da15b7cfeb492316997 240 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 180 197 - T 22-04-2016 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 L21SP4_RS11555 8739702044ad2da15b7cfeb492316997 240 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 7 235 38.514 T 22-04-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 L21SP4_RS11555 8739702044ad2da15b7cfeb492316997 240 Gene3D G3DSA:3.40.1180.10 4 237 1.5E-94 T 22-04-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 L21SP4_RS11555 8739702044ad2da15b7cfeb492316997 240 PANTHER PTHR10291 8 238 4.6E-110 T 22-04-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 L21SP4_RS11555 8739702044ad2da15b7cfeb492316997 240 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 8 234 1.3E-82 T 22-04-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 L21SP4_RS11555 8739702044ad2da15b7cfeb492316997 240 Pfam PF01255 Putative undecaprenyl diphosphate synthase 14 234 7.9E-77 T 22-04-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 L21SP4_RS11555 8739702044ad2da15b7cfeb492316997 240 SUPERFAMILY SSF64005 5 230 5.36E-81 T 22-04-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 L21SP4_RS04970 057fd54906fde9ea6a433052ecc2d685 266 PANTHER PTHR33969 1 265 4.0E-73 T 22-04-2016 L21SP4_RS04970 057fd54906fde9ea6a433052ecc2d685 266 Hamap MF_01805 Segregation and condensation protein A [scpA]. 14 249 23.105 T 22-04-2016 IPR003768 Segregation and condensation protein A L21SP4_RS04970 057fd54906fde9ea6a433052ecc2d685 266 PANTHER PTHR33969:SF2 1 265 4.0E-73 T 22-04-2016 L21SP4_RS04970 057fd54906fde9ea6a433052ecc2d685 266 Pfam PF02616 Segregation and condensation protein ScpA 31 245 1.1E-32 T 22-04-2016 IPR003768 Segregation and condensation protein A L21SP4_RS09720 38bb831e74c63f7a3ecbc342db60269b 1077 Pfam PF12831 FAD dependent oxidoreductase 207 282 6.0E-8 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP4_RS09720 38bb831e74c63f7a3ecbc342db60269b 1077 Pfam PF12831 FAD dependent oxidoreductase 493 640 5.5E-19 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP4_RS09720 38bb831e74c63f7a3ecbc342db60269b 1077 Pfam PF12831 FAD dependent oxidoreductase 696 824 3.4E-24 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP4_RS09720 38bb831e74c63f7a3ecbc342db60269b 1077 Gene3D G3DSA:3.50.50.60 202 276 3.8E-11 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP4_RS09720 38bb831e74c63f7a3ecbc342db60269b 1077 Gene3D G3DSA:3.50.50.60 366 439 3.8E-11 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP4_RS09720 38bb831e74c63f7a3ecbc342db60269b 1077 Gene3D G3DSA:3.50.50.60 2 43 3.8E-11 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP4_RS09720 38bb831e74c63f7a3ecbc342db60269b 1077 SUPERFAMILY SSF51905 491 639 2.11E-19 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP4_RS09720 38bb831e74c63f7a3ecbc342db60269b 1077 SUPERFAMILY SSF51905 748 803 2.11E-19 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP4_RS09720 38bb831e74c63f7a3ecbc342db60269b 1077 SUPERFAMILY SSF49785 78 196 1.17E-5 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS09720 38bb831e74c63f7a3ecbc342db60269b 1077 Gene3D G3DSA:2.60.120.260 68 196 3.2E-10 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS09720 38bb831e74c63f7a3ecbc342db60269b 1077 Gene3D G3DSA:3.50.50.60 491 624 7.6E-16 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP4_RS09720 38bb831e74c63f7a3ecbc342db60269b 1077 SUPERFAMILY SSF51905 2 48 7.26E-13 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP4_RS09720 38bb831e74c63f7a3ecbc342db60269b 1077 SUPERFAMILY SSF51905 110 157 7.26E-13 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP4_RS09720 38bb831e74c63f7a3ecbc342db60269b 1077 SUPERFAMILY SSF51905 380 437 7.26E-13 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP4_RS09720 38bb831e74c63f7a3ecbc342db60269b 1077 SUPERFAMILY SSF51905 335 352 7.26E-13 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP4_RS09720 38bb831e74c63f7a3ecbc342db60269b 1077 SUPERFAMILY SSF51905 215 297 7.26E-13 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP4_RS02700 d9d5405e1e99b8de37ab13ee0c5fc138 147 ProSitePatterns PS00648 Bacterial ribonuclease P protein component signature. 73 87 - T 22-04-2016 IPR020539 Ribonuclease P, conserved site GO:0004526 L21SP4_RS02700 d9d5405e1e99b8de37ab13ee0c5fc138 147 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 28 132 1.0E-14 T 22-04-2016 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 L21SP4_RS02700 d9d5405e1e99b8de37ab13ee0c5fc138 147 Pfam PF00825 Ribonuclease P 25 129 5.8E-21 T 22-04-2016 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 L21SP4_RS02700 d9d5405e1e99b8de37ab13ee0c5fc138 147 SUPERFAMILY SSF54211 25 133 6.32E-22 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold L21SP4_RS02700 d9d5405e1e99b8de37ab13ee0c5fc138 147 PANTHER PTHR33992 20 129 2.3E-21 T 22-04-2016 L21SP4_RS02700 d9d5405e1e99b8de37ab13ee0c5fc138 147 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 24 133 15.496 T 22-04-2016 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 L21SP4_RS02700 d9d5405e1e99b8de37ab13ee0c5fc138 147 Gene3D G3DSA:3.30.230.10 23 134 1.1E-23 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup L21SP4_RS08035 9bbafc3e3de1018422f382eac667dadd 440 SUPERFAMILY SSF53738 4 122 8.63E-36 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP4_RS08035 9bbafc3e3de1018422f382eac667dadd 440 SUPERFAMILY SSF55957 360 440 9.81E-20 T 22-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP4_RS08035 9bbafc3e3de1018422f382eac667dadd 440 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 365 439 8.6E-13 T 22-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP4_RS08035 9bbafc3e3de1018422f382eac667dadd 440 SUPERFAMILY SSF53738 150 248 2.51E-21 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP4_RS08035 9bbafc3e3de1018422f382eac667dadd 440 Gene3D G3DSA:3.40.120.10 243 360 1.5E-33 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP4_RS08035 9bbafc3e3de1018422f382eac667dadd 440 PANTHER PTHR22573:SF28 4 440 4.5E-129 T 22-04-2016 L21SP4_RS08035 9bbafc3e3de1018422f382eac667dadd 440 Gene3D G3DSA:3.40.120.10 4 141 3.1E-36 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP4_RS08035 9bbafc3e3de1018422f382eac667dadd 440 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 151 246 1.2E-16 T 22-04-2016 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP4_RS08035 9bbafc3e3de1018422f382eac667dadd 440 SUPERFAMILY SSF53738 252 355 3.18E-25 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP4_RS08035 9bbafc3e3de1018422f382eac667dadd 440 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 4 131 2.6E-35 T 22-04-2016 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP4_RS08035 9bbafc3e3de1018422f382eac667dadd 440 PANTHER PTHR22573 4 440 4.5E-129 T 22-04-2016 L21SP4_RS08035 9bbafc3e3de1018422f382eac667dadd 440 Gene3D G3DSA:3.30.310.50 362 439 2.0E-21 T 22-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP4_RS08035 9bbafc3e3de1018422f382eac667dadd 440 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 197 210 2.0E-12 T 22-04-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP4_RS08035 9bbafc3e3de1018422f382eac667dadd 440 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 89 103 2.0E-12 T 22-04-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP4_RS08035 9bbafc3e3de1018422f382eac667dadd 440 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 226 241 2.0E-12 T 22-04-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP4_RS08035 9bbafc3e3de1018422f382eac667dadd 440 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 165 184 2.0E-12 T 22-04-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP4_RS08035 9bbafc3e3de1018422f382eac667dadd 440 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 252 359 1.3E-21 T 22-04-2016 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP4_RS08035 9bbafc3e3de1018422f382eac667dadd 440 Gene3D G3DSA:3.40.120.10 167 242 5.0E-20 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP4_RS11015 dd22be4d1f3698361226756f64f80ff8 301 Gene3D G3DSA:3.40.50.300 1 184 3.1E-40 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS11015 dd22be4d1f3698361226756f64f80ff8 301 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 213 271 2.1E-5 T 22-04-2016 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal L21SP4_RS11015 dd22be4d1f3698361226756f64f80ff8 301 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 3 179 3.6E-30 T 22-04-2016 IPR003495 CobW/HypB/UreG, nucleotide-binding domain L21SP4_RS11015 dd22be4d1f3698361226756f64f80ff8 301 PANTHER PTHR13748:SF10 1 250 5.8E-42 T 22-04-2016 IPR012824 Cobalamin (vitamin B12) biosynthesis CobW GO:0009236 UniPathway: UPA00148 L21SP4_RS11015 dd22be4d1f3698361226756f64f80ff8 301 SUPERFAMILY SSF52540 3 186 9.46E-23 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS11015 dd22be4d1f3698361226756f64f80ff8 301 PANTHER PTHR13748 1 250 5.8E-42 T 22-04-2016 L21SP4_RS00975 8b1103dfd6223d84967044b9a0b6d806 395 PANTHER PTHR10859 10 289 2.2E-70 T 22-04-2016 L21SP4_RS00975 8b1103dfd6223d84967044b9a0b6d806 395 SUPERFAMILY SSF53448 11 239 1.29E-37 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases L21SP4_RS00975 8b1103dfd6223d84967044b9a0b6d806 395 Gene3D G3DSA:3.90.550.10 11 180 4.1E-17 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases L21SP4_RS00975 8b1103dfd6223d84967044b9a0b6d806 395 PANTHER PTHR10859:SF57 10 289 2.2E-70 T 22-04-2016 L21SP4_RS00975 8b1103dfd6223d84967044b9a0b6d806 395 Pfam PF00535 Glycosyl transferase family 2 12 173 1.8E-23 T 22-04-2016 IPR001173 Glycosyltransferase 2-like L21SP4_RS10010 cd5847e58ad37252a90f9d89f5ad783e 381 Gene3D G3DSA:3.40.50.150 259 368 1.3E-24 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS10010 cd5847e58ad37252a90f9d89f5ad783e 381 Gene3D G3DSA:3.40.50.150 155 221 1.3E-24 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS10010 cd5847e58ad37252a90f9d89f5ad783e 381 SUPERFAMILY SSF143437 91 161 9.94E-5 T 22-04-2016 L21SP4_RS10010 cd5847e58ad37252a90f9d89f5ad783e 381 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 307 313 - T 22-04-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 L21SP4_RS10010 cd5847e58ad37252a90f9d89f5ad783e 381 Pfam PF01170 Putative RNA methylase family UPF0020 169 370 5.6E-36 T 22-04-2016 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 L21SP4_RS10010 cd5847e58ad37252a90f9d89f5ad783e 381 Pfam PF02926 THUMP domain 28 161 2.8E-10 T 22-04-2016 IPR004114 THUMP domain GO:0003723 L21SP4_RS10010 cd5847e58ad37252a90f9d89f5ad783e 381 SMART SM00981 62 161 9.7E-20 T 22-04-2016 IPR004114 THUMP domain GO:0003723 L21SP4_RS10010 cd5847e58ad37252a90f9d89f5ad783e 381 SUPERFAMILY SSF53335 153 224 1.39E-39 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS10010 cd5847e58ad37252a90f9d89f5ad783e 381 SUPERFAMILY SSF53335 262 378 1.39E-39 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS10010 cd5847e58ad37252a90f9d89f5ad783e 381 PANTHER PTHR14911 9 219 4.5E-48 T 22-04-2016 L21SP4_RS10010 cd5847e58ad37252a90f9d89f5ad783e 381 PANTHER PTHR14911 259 368 4.5E-48 T 22-04-2016 L21SP4_RS10010 cd5847e58ad37252a90f9d89f5ad783e 381 PANTHER PTHR14911:SF13 9 219 4.5E-48 T 22-04-2016 L21SP4_RS10010 cd5847e58ad37252a90f9d89f5ad783e 381 PANTHER PTHR14911:SF13 259 368 4.5E-48 T 22-04-2016 L21SP4_RS06990 3e697d98b196e41140b298a6872ff704 202 SUPERFAMILY SSF52833 34 201 1.5E-42 T 22-04-2016 IPR012336 Thioredoxin-like fold L21SP4_RS06990 3e697d98b196e41140b298a6872ff704 202 Gene3D G3DSA:3.40.30.10 37 194 2.1E-24 T 22-04-2016 IPR012336 Thioredoxin-like fold L21SP4_RS06990 3e697d98b196e41140b298a6872ff704 202 Pfam PF00578 AhpC/TSA family 37 155 5.5E-17 T 22-04-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15 L21SP4_RS06990 3e697d98b196e41140b298a6872ff704 202 PANTHER PTHR10681:SF91 25 200 2.7E-38 T 22-04-2016 L21SP4_RS06990 3e697d98b196e41140b298a6872ff704 202 PANTHER PTHR10681 25 200 2.7E-38 T 22-04-2016 L21SP4_RS03470 c19991df0f27dc30ef6072dec86bee94 771 Hamap MF_00172 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [metE]. 2 762 37.013 T 22-04-2016 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702|UniPathway: UPA00051 L21SP4_RS03470 c19991df0f27dc30ef6072dec86bee94 771 Gene3D G3DSA:3.20.20.210 3 394 4.9E-151 T 22-04-2016 L21SP4_RS03470 c19991df0f27dc30ef6072dec86bee94 771 PIRSF PIRSF000382 1 767 0.0 T 22-04-2016 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702|UniPathway: UPA00051 L21SP4_RS03470 c19991df0f27dc30ef6072dec86bee94 771 PANTHER PTHR30519:SF0 1 767 0.0 T 22-04-2016 L21SP4_RS03470 c19991df0f27dc30ef6072dec86bee94 771 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 435 757 8.3E-156 T 22-04-2016 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702|UniPathway: UPA00051 L21SP4_RS03470 c19991df0f27dc30ef6072dec86bee94 771 SUPERFAMILY SSF51726 4 398 8.76E-111 T 22-04-2016 L21SP4_RS03470 c19991df0f27dc30ef6072dec86bee94 771 PANTHER PTHR30519 1 767 0.0 T 22-04-2016 L21SP4_RS03470 c19991df0f27dc30ef6072dec86bee94 771 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 4 318 3.4E-114 T 22-04-2016 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702|UniPathway: UPA00051 L21SP4_RS03470 c19991df0f27dc30ef6072dec86bee94 771 Gene3D G3DSA:3.20.20.210 396 763 3.5E-132 T 22-04-2016 L21SP4_RS03470 c19991df0f27dc30ef6072dec86bee94 771 SUPERFAMILY SSF51726 400 761 2.75E-119 T 22-04-2016 L21SP4_RS03470 c19991df0f27dc30ef6072dec86bee94 771 TIGRFAM TIGR01371 met_syn_B12ind: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 7 762 0.0 T 22-04-2016 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702|UniPathway: UPA00051 L21SP4_RS10120 eb93ee2cdb64a068be93bd3aa6efcd7b 105 SUPERFAMILY SSF51182 3 104 2.67E-23 T 22-04-2016 IPR011051 RmlC-like cupin domain L21SP4_RS10120 eb93ee2cdb64a068be93bd3aa6efcd7b 105 Gene3D G3DSA:2.60.120.10 2 104 6.2E-36 T 22-04-2016 IPR014710 RmlC-like jelly roll fold L21SP4_RS10120 eb93ee2cdb64a068be93bd3aa6efcd7b 105 Pfam PF07883 Cupin domain 36 101 1.8E-10 T 22-04-2016 IPR013096 Cupin 2, conserved barrel L21SP4_RS10120 eb93ee2cdb64a068be93bd3aa6efcd7b 105 PANTHER PTHR37694 1 105 8.9E-30 T 22-04-2016 L21SP4_RS11840 5e534f89a958bbc490e383a0c53a6549 109 Gene3D G3DSA:1.10.10.60 9 92 4.8E-6 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS11840 5e534f89a958bbc490e383a0c53a6549 109 PANTHER PTHR33215:SF2 1 106 1.2E-18 T 22-04-2016 L21SP4_RS11840 5e534f89a958bbc490e383a0c53a6549 109 PANTHER PTHR33215 1 106 1.2E-18 T 22-04-2016 L21SP4_RS11840 5e534f89a958bbc490e383a0c53a6549 109 SUPERFAMILY SSF48295 1 61 4.03E-12 T 22-04-2016 IPR010921 Trp repressor/replication initiator GO:0043565 L21SP4_RS11840 5e534f89a958bbc490e383a0c53a6549 109 Pfam PF01527 Transposase 4 55 3.1E-8 T 22-04-2016 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 L21SP4_RS00305 71d7dd7cbfbf54b913a0a8b83f4766db 245 SUPERFAMILY SSF74653 68 81 2.22E-15 T 22-04-2016 L21SP4_RS00305 71d7dd7cbfbf54b913a0a8b83f4766db 245 SUPERFAMILY SSF74653 144 245 2.22E-15 T 22-04-2016 L21SP4_RS00305 71d7dd7cbfbf54b913a0a8b83f4766db 245 Gene3D G3DSA:3.30.1150.10 136 245 2.6E-21 T 22-04-2016 L21SP4_RS00305 71d7dd7cbfbf54b913a0a8b83f4766db 245 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 175 244 2.8E-11 T 22-04-2016 IPR006260 TonB, C-terminal GO:0006810 L21SP4_RS00305 71d7dd7cbfbf54b913a0a8b83f4766db 245 Pfam PF13103 TonB C terminal 155 239 1.7E-11 T 22-04-2016 IPR006260 TonB, C-terminal GO:0006810 L21SP4_RS02860 85812f32c7a64fd57c0e32a8de7fce61 391 Hamap MF_00426 Na(+)-translocating NADH-quinone reductase subunit B [nqrB]. 4 385 34.675 T 22-04-2016 IPR010966 Na(+)-translocating NADH-quinone reductase subunit B GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0022904|GO:0055114 L21SP4_RS02860 85812f32c7a64fd57c0e32a8de7fce61 391 PANTHER PTHR30578 7 387 1.0E-169 T 22-04-2016 L21SP4_RS02860 85812f32c7a64fd57c0e32a8de7fce61 391 TIGRFAM TIGR01937 nqrB: NADH:ubiquinone oxidoreductase, Na(+)-translocating, B subunit 87 381 5.6E-115 T 22-04-2016 IPR010966 Na(+)-translocating NADH-quinone reductase subunit B GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0022904|GO:0055114 L21SP4_RS02860 85812f32c7a64fd57c0e32a8de7fce61 391 PANTHER PTHR30578:SF1 7 387 1.0E-169 T 22-04-2016 IPR010966 Na(+)-translocating NADH-quinone reductase subunit B GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0022904|GO:0055114 L21SP4_RS02860 85812f32c7a64fd57c0e32a8de7fce61 391 PIRSF PIRSF016055 5 387 2.8E-152 T 22-04-2016 IPR010966 Na(+)-translocating NADH-quinone reductase subunit B GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0022904|GO:0055114 L21SP4_RS02860 85812f32c7a64fd57c0e32a8de7fce61 391 Pfam PF03116 NQR2, RnfD, RnfE family 43 376 6.2E-102 T 22-04-2016 IPR004338 NADH-quinone reductase NQR2/RnfD GO:0006810|GO:0016020 L21SP4_RS10620 02b69e995d12d58804210523a1489b76 794 Gene3D G3DSA:3.90.199.10 446 498 2.3E-60 T 22-04-2016 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 L21SP4_RS10620 02b69e995d12d58804210523a1489b76 794 Gene3D G3DSA:3.90.199.10 167 357 2.3E-60 T 22-04-2016 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 L21SP4_RS10620 02b69e995d12d58804210523a1489b76 794 Gene3D G3DSA:3.30.1360.40 358 444 4.3E-11 T 22-04-2016 IPR024946 Arginine repressor C-terminal-like domain L21SP4_RS10620 02b69e995d12d58804210523a1489b76 794 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 168 584 2.4E-105 T 22-04-2016 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 L21SP4_RS10620 02b69e995d12d58804210523a1489b76 794 PANTHER PTHR10169:SF48 156 465 1.5E-95 T 22-04-2016 L21SP4_RS10620 02b69e995d12d58804210523a1489b76 794 PANTHER PTHR10169 156 465 1.5E-95 T 22-04-2016 L21SP4_RS10620 02b69e995d12d58804210523a1489b76 794 SMART SM00434 147 584 4.4E-102 T 22-04-2016 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 L21SP4_RS10620 02b69e995d12d58804210523a1489b76 794 SUPERFAMILY SSF56719 149 602 1.96E-105 T 22-04-2016 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 L21SP4_RS00215 8bf19b41e15e661d94782c8c21d81a92 449 Pfam PF00815 Histidinol dehydrogenase 40 442 6.7E-144 T 22-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 L21SP4_RS00215 8bf19b41e15e661d94782c8c21d81a92 449 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 18 442 36.267 T 22-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 L21SP4_RS00215 8bf19b41e15e661d94782c8c21d81a92 449 PIRSF PIRSF000099 21 444 9.7E-142 T 22-04-2016 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 L21SP4_RS00215 8bf19b41e15e661d94782c8c21d81a92 449 PANTHER PTHR21256 24 448 1.6E-167 T 22-04-2016 L21SP4_RS00215 8bf19b41e15e661d94782c8c21d81a92 449 PRINTS PR00083 Histidinol dehydrogenase signature 214 239 2.6E-76 T 22-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 L21SP4_RS00215 8bf19b41e15e661d94782c8c21d81a92 449 PRINTS PR00083 Histidinol dehydrogenase signature 184 210 2.6E-76 T 22-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 L21SP4_RS00215 8bf19b41e15e661d94782c8c21d81a92 449 PRINTS PR00083 Histidinol dehydrogenase signature 243 264 2.6E-76 T 22-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 L21SP4_RS00215 8bf19b41e15e661d94782c8c21d81a92 449 PRINTS PR00083 Histidinol dehydrogenase signature 265 284 2.6E-76 T 22-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 L21SP4_RS00215 8bf19b41e15e661d94782c8c21d81a92 449 PRINTS PR00083 Histidinol dehydrogenase signature 376 394 2.6E-76 T 22-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 L21SP4_RS00215 8bf19b41e15e661d94782c8c21d81a92 449 PRINTS PR00083 Histidinol dehydrogenase signature 149 175 2.6E-76 T 22-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 L21SP4_RS00215 8bf19b41e15e661d94782c8c21d81a92 449 PRINTS PR00083 Histidinol dehydrogenase signature 335 360 2.6E-76 T 22-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 L21SP4_RS00215 8bf19b41e15e661d94782c8c21d81a92 449 PRINTS PR00083 Histidinol dehydrogenase signature 46 70 2.6E-76 T 22-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 L21SP4_RS00215 8bf19b41e15e661d94782c8c21d81a92 449 SUPERFAMILY SSF53720 36 442 1.9E-67 T 22-04-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 L21SP4_RS00215 8bf19b41e15e661d94782c8c21d81a92 449 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 47 441 2.3E-138 T 22-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 L21SP4_RS00215 8bf19b41e15e661d94782c8c21d81a92 449 Gene3D G3DSA:3.40.50.1980 40 253 2.1E-69 T 22-04-2016 L21SP4_RS11860 50b1722b85ef6b12944f5b1b150dc5b3 319 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 25 302 6.7E-78 T 22-04-2016 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 L21SP4_RS11860 50b1722b85ef6b12944f5b1b150dc5b3 319 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 26 280 1.6E-71 T 22-04-2016 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 L21SP4_RS11860 50b1722b85ef6b12944f5b1b150dc5b3 319 PIRSF PIRSF006470 5 318 6.2E-90 T 22-04-2016 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 L21SP4_RS11860 50b1722b85ef6b12944f5b1b150dc5b3 319 PANTHER PTHR33376:SF6 16 315 1.0E-100 T 22-04-2016 L21SP4_RS11860 50b1722b85ef6b12944f5b1b150dc5b3 319 SUPERFAMILY SSF53850 128 254 6.27E-6 T 22-04-2016 L21SP4_RS11860 50b1722b85ef6b12944f5b1b150dc5b3 319 PANTHER PTHR33376 16 315 1.0E-100 T 22-04-2016 L21SP4_RS07440 6a42ee9869b99cb3446c98d52c22cfae 1243 SUPERFAMILY SSF81593 1103 1241 3.77E-31 T 22-04-2016 L21SP4_RS07440 6a42ee9869b99cb3446c98d52c22cfae 1243 Pfam PF08335 GlnD PII-uridylyltransferase 1109 1238 7.4E-29 T 22-04-2016 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 L21SP4_RS07440 6a42ee9869b99cb3446c98d52c22cfae 1243 Pfam PF08335 GlnD PII-uridylyltransferase 613 741 1.7E-18 T 22-04-2016 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 L21SP4_RS07440 6a42ee9869b99cb3446c98d52c22cfae 1243 Gene3D G3DSA:3.30.460.10 936 1088 1.7E-39 T 22-04-2016 L21SP4_RS07440 6a42ee9869b99cb3446c98d52c22cfae 1243 Gene3D G3DSA:3.30.460.10 417 588 1.4E-42 T 22-04-2016 L21SP4_RS07440 6a42ee9869b99cb3446c98d52c22cfae 1243 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 331 580 3.5E-40 T 22-04-2016 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 L21SP4_RS07440 6a42ee9869b99cb3446c98d52c22cfae 1243 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 855 1082 1.7E-47 T 22-04-2016 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 L21SP4_RS07440 6a42ee9869b99cb3446c98d52c22cfae 1243 PANTHER PTHR30621 241 1235 1.0E-139 T 22-04-2016 L21SP4_RS07440 6a42ee9869b99cb3446c98d52c22cfae 1243 SUPERFAMILY SSF81301 837 1088 6.21E-55 T 22-04-2016 L21SP4_RS07440 6a42ee9869b99cb3446c98d52c22cfae 1243 Gene3D G3DSA:3.30.70.260 213 274 7.2E-4 T 22-04-2016 L21SP4_RS07440 6a42ee9869b99cb3446c98d52c22cfae 1243 SUPERFAMILY SSF81301 320 587 3.6E-46 T 22-04-2016 L21SP4_RS07440 6a42ee9869b99cb3446c98d52c22cfae 1243 SUPERFAMILY SSF81593 596 740 7.3E-22 T 22-04-2016 L21SP4_RS11245 bb5f99f00051e09d696fb854e632bff3 611 Pfam PF16889 Heparinase II/III N-terminus 64 326 7.2E-28 T 22-04-2016 IPR031680 Heparin-sulfate lyase, N-terminal MetaCyc: PWY-7651 L21SP4_RS11245 bb5f99f00051e09d696fb854e632bff3 611 Gene3D G3DSA:1.50.10.110 113 318 2.4E-14 T 22-04-2016 IPR008397 Alginate lyase domain GO:0016829|GO:0042597 KEGG: 00051+4.2.2.3|MetaCyc: PWY-6986 L21SP4_RS11245 bb5f99f00051e09d696fb854e632bff3 611 Pfam PF07940 Heparinase II/III-like protein 376 586 9.0E-34 T 22-04-2016 IPR012480 Heparinase II/III-like MetaCyc: PWY-7651 L21SP4_RS11245 bb5f99f00051e09d696fb854e632bff3 611 PANTHER PTHR39210 66 556 3.2E-41 T 22-04-2016 L21SP4_RS11245 bb5f99f00051e09d696fb854e632bff3 611 SUPERFAMILY SSF48230 74 329 5.68E-37 T 22-04-2016 IPR008929 Chondroitin AC/alginate lyase L21SP4_RS10240 4018a4244abfb327abfbe3193b025e2f 390 Pfam PF01546 Peptidase family M20/M25/M40 81 389 1.7E-23 T 22-04-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 L21SP4_RS10240 4018a4244abfb327abfbe3193b025e2f 390 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 80 89 - T 22-04-2016 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 L21SP4_RS10240 4018a4244abfb327abfbe3193b025e2f 390 SUPERFAMILY SSF55031 186 289 1.83E-15 T 22-04-2016 IPR011650 Peptidase M20, dimerisation domain L21SP4_RS10240 4018a4244abfb327abfbe3193b025e2f 390 SUPERFAMILY SSF53187 10 186 3.14E-57 T 22-04-2016 L21SP4_RS10240 4018a4244abfb327abfbe3193b025e2f 390 SUPERFAMILY SSF53187 309 389 3.14E-57 T 22-04-2016 L21SP4_RS10240 4018a4244abfb327abfbe3193b025e2f 390 PANTHER PTHR11014:SF61 6 389 2.6E-97 T 22-04-2016 L21SP4_RS10240 4018a4244abfb327abfbe3193b025e2f 390 PANTHER PTHR11014 6 389 2.6E-97 T 22-04-2016 L21SP4_RS10240 4018a4244abfb327abfbe3193b025e2f 390 Pfam PF07687 Peptidase dimerisation domain 185 288 4.4E-10 T 22-04-2016 IPR011650 Peptidase M20, dimerisation domain L21SP4_RS10240 4018a4244abfb327abfbe3193b025e2f 390 Gene3D G3DSA:3.30.70.360 187 289 6.9E-19 T 22-04-2016 IPR011650 Peptidase M20, dimerisation domain L21SP4_RS10240 4018a4244abfb327abfbe3193b025e2f 390 Gene3D G3DSA:3.40.630.10 309 389 5.2E-60 T 22-04-2016 L21SP4_RS10240 4018a4244abfb327abfbe3193b025e2f 390 Gene3D G3DSA:3.40.630.10 6 186 5.2E-60 T 22-04-2016 L21SP4_RS03495 707e70e237afc173796886a01eeaf045 1057 Gene3D G3DSA:3.30.2090.10 187 271 6.5E-10 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains L21SP4_RS03495 707e70e237afc173796886a01eeaf045 1057 Gene3D G3DSA:1.10.3850.10 810 1029 8.8E-57 T 22-04-2016 L21SP4_RS03495 707e70e237afc173796886a01eeaf045 1057 Pfam PF00873 AcrB/AcrD/AcrF family 19 1027 4.3E-167 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 L21SP4_RS03495 707e70e237afc173796886a01eeaf045 1057 Gene3D G3DSA:3.30.70.1320 162 182 3.5E-7 T 22-04-2016 L21SP4_RS03495 707e70e237afc173796886a01eeaf045 1057 Gene3D G3DSA:3.30.70.1320 275 308 3.5E-7 T 22-04-2016 L21SP4_RS03495 707e70e237afc173796886a01eeaf045 1057 SUPERFAMILY SSF82693 273 329 4.87E-12 T 22-04-2016 L21SP4_RS03495 707e70e237afc173796886a01eeaf045 1057 SUPERFAMILY SSF82693 148 185 4.87E-12 T 22-04-2016 L21SP4_RS03495 707e70e237afc173796886a01eeaf045 1057 Gene3D G3DSA:1.20.1640.10 309 492 1.4E-47 T 22-04-2016 L21SP4_RS03495 707e70e237afc173796886a01eeaf045 1057 SUPERFAMILY SSF82693 571 667 2.88E-6 T 22-04-2016 L21SP4_RS03495 707e70e237afc173796886a01eeaf045 1057 Gene3D G3DSA:3.30.70.1430 49 146 2.9E-21 T 22-04-2016 L21SP4_RS03495 707e70e237afc173796886a01eeaf045 1057 SUPERFAMILY SSF82866 807 1029 2.22E-47 T 22-04-2016 L21SP4_RS03495 707e70e237afc173796886a01eeaf045 1057 SUPERFAMILY SSF82693 49 138 9.07E-20 T 22-04-2016 L21SP4_RS03495 707e70e237afc173796886a01eeaf045 1057 SUPERFAMILY SSF82866 299 490 1.96E-41 T 22-04-2016 L21SP4_RS03495 707e70e237afc173796886a01eeaf045 1057 Gene3D G3DSA:3.30.2090.10 731 797 4.3E-7 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains L21SP4_RS03495 707e70e237afc173796886a01eeaf045 1057 PRINTS PR00702 Acriflavin resistance protein family signature 361 382 2.7E-25 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 L21SP4_RS03495 707e70e237afc173796886a01eeaf045 1057 PRINTS PR00702 Acriflavin resistance protein family signature 467 490 2.7E-25 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 L21SP4_RS03495 707e70e237afc173796886a01eeaf045 1057 PRINTS PR00702 Acriflavin resistance protein family signature 46 64 2.7E-25 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 L21SP4_RS03495 707e70e237afc173796886a01eeaf045 1057 PRINTS PR00702 Acriflavin resistance protein family signature 442 465 2.7E-25 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 L21SP4_RS03495 707e70e237afc173796886a01eeaf045 1057 PRINTS PR00702 Acriflavin resistance protein family signature 389 413 2.7E-25 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 L21SP4_RS03495 707e70e237afc173796886a01eeaf045 1057 PANTHER PTHR32063 10 1037 0.0 T 22-04-2016 L21SP4_RS03495 707e70e237afc173796886a01eeaf045 1057 SUPERFAMILY SSF82714 732 800 2.75E-7 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains L21SP4_RS03495 707e70e237afc173796886a01eeaf045 1057 SUPERFAMILY SSF82714 189 269 8.11E-12 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains L21SP4_RS03495 707e70e237afc173796886a01eeaf045 1057 PANTHER PTHR32063:SF33 10 1037 0.0 T 22-04-2016 L21SP4_RS03915 c256874946feb341250e7208a2734bf7 404 Pfam PF01609 Transposase DDE domain 81 331 6.2E-8 T 22-04-2016 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 L21SP4_RS03915 c256874946feb341250e7208a2734bf7 404 SUPERFAMILY SSF53098 77 337 5.39E-19 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS03915 c256874946feb341250e7208a2734bf7 404 Gene3D G3DSA:3.90.350.10 77 313 2.8E-17 T 22-04-2016 IPR014736 Transposase, Tn5-like, core L21SP4_RS06315 9b2d3fae100870d22b4d7f2e50c9b508 166 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 29 92 4.6E-16 T 22-04-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 L21SP4_RS06315 9b2d3fae100870d22b4d7f2e50c9b508 166 SUPERFAMILY SSF52374 28 156 7.51E-24 T 22-04-2016 L21SP4_RS06315 9b2d3fae100870d22b4d7f2e50c9b508 166 PANTHER PTHR10739 19 157 2.8E-36 T 22-04-2016 L21SP4_RS06315 9b2d3fae100870d22b4d7f2e50c9b508 166 Pfam PF01467 Cytidylyltransferase-like 31 125 8.1E-17 T 22-04-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 L21SP4_RS06315 9b2d3fae100870d22b4d7f2e50c9b508 166 PANTHER PTHR10739:SF26 19 157 2.8E-36 T 22-04-2016 L21SP4_RS06315 9b2d3fae100870d22b4d7f2e50c9b508 166 Gene3D G3DSA:3.40.50.620 27 144 9.7E-31 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP4_RS04845 5f68ce6fb1b5b2f9ccd7f0854d20a5b2 542 Gene3D G3DSA:3.30.360.10 219 520 2.2E-108 T 22-04-2016 L21SP4_RS04845 5f68ce6fb1b5b2f9ccd7f0854d20a5b2 542 SUPERFAMILY SSF51735 23 222 3.35E-55 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS04845 5f68ce6fb1b5b2f9ccd7f0854d20a5b2 542 PIRSF PIRSF000110 10 524 4.2E-162 T 22-04-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 L21SP4_RS04845 5f68ce6fb1b5b2f9ccd7f0854d20a5b2 542 Gene3D G3DSA:3.40.50.720 28 218 2.9E-62 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS04845 5f68ce6fb1b5b2f9ccd7f0854d20a5b2 542 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 221 519 7.4E-102 T 22-04-2016 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 L21SP4_RS04845 5f68ce6fb1b5b2f9ccd7f0854d20a5b2 542 SUPERFAMILY SSF55347 209 520 1.93E-100 T 22-04-2016 L21SP4_RS04845 5f68ce6fb1b5b2f9ccd7f0854d20a5b2 542 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 252 269 2.0E-44 T 22-04-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 L21SP4_RS04845 5f68ce6fb1b5b2f9ccd7f0854d20a5b2 542 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 199 227 2.0E-44 T 22-04-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 L21SP4_RS04845 5f68ce6fb1b5b2f9ccd7f0854d20a5b2 542 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 362 388 2.0E-44 T 22-04-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 L21SP4_RS04845 5f68ce6fb1b5b2f9ccd7f0854d20a5b2 542 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 175 188 2.0E-44 T 22-04-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 L21SP4_RS04845 5f68ce6fb1b5b2f9ccd7f0854d20a5b2 542 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 270 286 2.0E-44 T 22-04-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 L21SP4_RS04845 5f68ce6fb1b5b2f9ccd7f0854d20a5b2 542 PANTHER PTHR23429:SF0 27 519 6.0E-201 T 22-04-2016 L21SP4_RS04845 5f68ce6fb1b5b2f9ccd7f0854d20a5b2 542 PANTHER PTHR23429 27 519 6.0E-201 T 22-04-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 L21SP4_RS04845 5f68ce6fb1b5b2f9ccd7f0854d20a5b2 542 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 32 219 2.4E-55 T 22-04-2016 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 L21SP4_RS04845 5f68ce6fb1b5b2f9ccd7f0854d20a5b2 542 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 28 519 9.8E-165 T 22-04-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 L21SP4_RS04845 5f68ce6fb1b5b2f9ccd7f0854d20a5b2 542 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 28 526 75.056 T 22-04-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 L21SP4_RS09570 0cdbb6ea88bab0774dbe1e62ad8e5473 224 SUPERFAMILY SSF52317 2 210 1.13E-58 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like L21SP4_RS09570 0cdbb6ea88bab0774dbe1e62ad8e5473 224 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 1 209 33.986 T 22-04-2016 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 UniPathway: UPA00031 L21SP4_RS09570 0cdbb6ea88bab0774dbe1e62ad8e5473 224 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 2 208 3.5E-62 T 22-04-2016 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 UniPathway: UPA00031 L21SP4_RS09570 0cdbb6ea88bab0774dbe1e62ad8e5473 224 PANTHER PTHR21235:SF1 4 208 1.5E-75 T 22-04-2016 L21SP4_RS09570 0cdbb6ea88bab0774dbe1e62ad8e5473 224 Gene3D G3DSA:3.40.50.880 1 212 2.1E-79 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like L21SP4_RS09570 0cdbb6ea88bab0774dbe1e62ad8e5473 224 PANTHER PTHR21235 4 208 1.5E-75 T 22-04-2016 L21SP4_RS09570 0cdbb6ea88bab0774dbe1e62ad8e5473 224 Pfam PF00117 Glutamine amidotransferase class-I 6 206 4.2E-18 T 22-04-2016 IPR017926 Glutamine amidotransferase Reactome: REACT_1698 L21SP4_RS09570 0cdbb6ea88bab0774dbe1e62ad8e5473 224 PIRSF PIRSF000495 1 212 1.1E-66 T 22-04-2016 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 UniPathway: UPA00031 L21SP4_RS11830 1de586a78ddb29dec79bac2ac321d41c 116 PANTHER PTHR34580:SF1 16 109 1.1E-20 T 22-04-2016 L21SP4_RS11830 1de586a78ddb29dec79bac2ac321d41c 116 PANTHER PTHR34580 16 109 1.1E-20 T 22-04-2016 L21SP4_RS11830 1de586a78ddb29dec79bac2ac321d41c 116 Pfam PF13280 WYL domain 15 110 1.1E-20 T 22-04-2016 IPR026881 WYL domain L21SP4_RS07430 cb8a3698d35ab6e68e1aed124edc936f 376 Pfam PF16491 CAAX prenyl protease N-terminal, five membrane helices 9 165 1.0E-23 T 22-04-2016 IPR032456 CAAX prenyl protease 1, N-terminal KEGG: 00900+3.4.24.84 L21SP4_RS07430 cb8a3698d35ab6e68e1aed124edc936f 376 Gene3D G3DSA:3.30.2010.10 164 253 8.9E-15 T 22-04-2016 L21SP4_RS07430 cb8a3698d35ab6e68e1aed124edc936f 376 PANTHER PTHR10120:SF24 12 370 4.1E-64 T 22-04-2016 IPR027057 CAAX prenyl protease 1 GO:0008233|GO:0071586 KEGG: 00900+3.4.24.84 L21SP4_RS07430 cb8a3698d35ab6e68e1aed124edc936f 376 Pfam PF01435 Peptidase family M48 169 370 4.1E-31 T 22-04-2016 IPR001915 Peptidase M48 GO:0004222|GO:0006508 L21SP4_RS07430 cb8a3698d35ab6e68e1aed124edc936f 376 PANTHER PTHR10120 12 370 4.1E-64 T 22-04-2016 L21SP4_RS03045 92c65e61038f9f6af06f8b6efe7ad68b 153 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 153 61.012 T 22-04-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 L21SP4_RS03045 92c65e61038f9f6af06f8b6efe7ad68b 153 SUPERFAMILY SSF52304 1 151 1.83E-51 T 22-04-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 L21SP4_RS03045 92c65e61038f9f6af06f8b6efe7ad68b 153 PANTHER PTHR21272 1 150 1.7E-63 T 22-04-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 L21SP4_RS03045 92c65e61038f9f6af06f8b6efe7ad68b 153 PIRSF PIRSF001399 1 153 6.2E-52 T 22-04-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 L21SP4_RS03045 92c65e61038f9f6af06f8b6efe7ad68b 153 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 3 146 4.0E-33 T 22-04-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 L21SP4_RS03045 92c65e61038f9f6af06f8b6efe7ad68b 153 Gene3D G3DSA:3.40.50.9100 1 151 3.0E-54 T 22-04-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 L21SP4_RS03045 92c65e61038f9f6af06f8b6efe7ad68b 153 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 3 149 3.0E-51 T 22-04-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 L21SP4_RS03045 92c65e61038f9f6af06f8b6efe7ad68b 153 Pfam PF01220 Dehydroquinase class II 2 146 9.5E-49 T 22-04-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 L21SP4_RS03045 92c65e61038f9f6af06f8b6efe7ad68b 153 ProSitePatterns PS01029 Dehydroquinase class II signature. 6 23 - T 22-04-2016 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 L21SP4_RS01215 d63854a6e4036a8464f8a8caf5c3d57d 254 PANTHER PTHR30294 12 249 2.0E-24 T 22-04-2016 L21SP4_RS01215 d63854a6e4036a8464f8a8caf5c3d57d 254 PANTHER PTHR30294:SF5 12 249 2.0E-24 T 22-04-2016 L21SP4_RS01215 d63854a6e4036a8464f8a8caf5c3d57d 254 Pfam PF12730 ABC-2 family transporter protein 13 170 3.9E-9 T 22-04-2016 IPR032688 ABC-2 family transporter protein GO:0006810 L21SP4_RS05400 97e2d88eff384fcc2e8ef4a5f4ce243a 224 Pfam PF13419 Haloacid dehalogenase-like hydrolase 8 185 4.0E-38 T 22-04-2016 IPR023214 HAD-like domain L21SP4_RS05400 97e2d88eff384fcc2e8ef4a5f4ce243a 224 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 130 146 1.5E-9 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 L21SP4_RS05400 97e2d88eff384fcc2e8ef4a5f4ce243a 224 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 5 16 1.5E-9 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 L21SP4_RS05400 97e2d88eff384fcc2e8ef4a5f4ce243a 224 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 99 112 1.5E-9 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 L21SP4_RS05400 97e2d88eff384fcc2e8ef4a5f4ce243a 224 SUPERFAMILY SSF56784 4 211 9.32E-55 T 22-04-2016 IPR023214 HAD-like domain L21SP4_RS05400 97e2d88eff384fcc2e8ef4a5f4ce243a 224 PANTHER PTHR18901 6 210 1.2E-49 T 22-04-2016 L21SP4_RS05400 97e2d88eff384fcc2e8ef4a5f4ce243a 224 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 88 180 4.1E-7 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 L21SP4_RS05400 97e2d88eff384fcc2e8ef4a5f4ce243a 224 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 81 184 1.4E-12 T 22-04-2016 IPR006549 HAD-superfamily hydrolase,subfamily IIIA L21SP4_RS05400 97e2d88eff384fcc2e8ef4a5f4ce243a 224 PANTHER PTHR18901:SF14 6 210 1.2E-49 T 22-04-2016 L21SP4_RS05400 97e2d88eff384fcc2e8ef4a5f4ce243a 224 Gene3D G3DSA:3.40.50.1000 4 22 1.1E-41 T 22-04-2016 IPR023214 HAD-like domain L21SP4_RS05400 97e2d88eff384fcc2e8ef4a5f4ce243a 224 Gene3D G3DSA:3.40.50.1000 83 210 1.1E-41 T 22-04-2016 IPR023214 HAD-like domain L21SP4_RS05400 97e2d88eff384fcc2e8ef4a5f4ce243a 224 Gene3D G3DSA:1.10.150.240 23 82 2.5E-14 T 22-04-2016 IPR023198 Phosphoglycolate phosphatase, domain 2 L21SP4_RS04900 9c0431553b89db05c693eb5ea68dc7b7 344 PANTHER PTHR19375:SF117 9 327 1.1E-172 T 22-04-2016 L21SP4_RS04900 9c0431553b89db05c693eb5ea68dc7b7 344 SUPERFAMILY SSF53067 9 147 2.65E-42 T 22-04-2016 L21SP4_RS04900 9c0431553b89db05c693eb5ea68dc7b7 344 SUPERFAMILY SSF53067 148 333 3.95E-49 T 22-04-2016 L21SP4_RS04900 9c0431553b89db05c693eb5ea68dc7b7 344 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 131 150 4.7E-62 T 22-04-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 L21SP4_RS04900 9c0431553b89db05c693eb5ea68dc7b7 344 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 186 206 4.7E-62 T 22-04-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 L21SP4_RS04900 9c0431553b89db05c693eb5ea68dc7b7 344 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 48 66 4.7E-62 T 22-04-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 L21SP4_RS04900 9c0431553b89db05c693eb5ea68dc7b7 344 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 299 325 4.7E-62 T 22-04-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 L21SP4_RS04900 9c0431553b89db05c693eb5ea68dc7b7 344 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 68 91 4.7E-62 T 22-04-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 L21SP4_RS04900 9c0431553b89db05c693eb5ea68dc7b7 344 Gene3D G3DSA:3.30.420.40 159 185 8.6E-32 T 22-04-2016 L21SP4_RS04900 9c0431553b89db05c693eb5ea68dc7b7 344 Gene3D G3DSA:3.30.420.40 262 316 8.6E-32 T 22-04-2016 L21SP4_RS04900 9c0431553b89db05c693eb5ea68dc7b7 344 Gene3D G3DSA:3.30.420.40 10 158 1.3E-48 T 22-04-2016 L21SP4_RS04900 9c0431553b89db05c693eb5ea68dc7b7 344 Gene3D G3DSA:3.90.640.10 186 258 3.4E-32 T 22-04-2016 L21SP4_RS04900 9c0431553b89db05c693eb5ea68dc7b7 344 PANTHER PTHR19375 9 327 1.1E-172 T 22-04-2016 L21SP4_RS04900 9c0431553b89db05c693eb5ea68dc7b7 344 Pfam PF06723 MreB/Mbl protein 11 333 1.6E-151 T 22-04-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 L21SP4_RS04900 9c0431553b89db05c693eb5ea68dc7b7 344 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 9 334 1.9E-159 T 22-04-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 L21SP4_RS11190 ae857bffea4ad7195455329294205645 314 PANTHER PTHR10366:SF41 4 306 1.4E-110 T 22-04-2016 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 L21SP4_RS11190 ae857bffea4ad7195455329294205645 314 PANTHER PTHR10366 4 306 1.4E-110 T 22-04-2016 L21SP4_RS11190 ae857bffea4ad7195455329294205645 314 Gene3D G3DSA:3.90.25.10 178 309 2.5E-36 T 22-04-2016 L21SP4_RS11190 ae857bffea4ad7195455329294205645 314 SUPERFAMILY SSF51735 2 308 1.3E-81 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS11190 ae857bffea4ad7195455329294205645 314 Pfam PF16363 GDP-mannose 4,6 dehydratase 6 298 6.1E-64 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS11190 ae857bffea4ad7195455329294205645 314 Gene3D G3DSA:3.40.50.720 2 177 4.6E-51 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS07740 80b1b4c4764b07614a42fab91f76d91e 601 PANTHER PTHR24222 1 601 7.2E-305 T 22-04-2016 L21SP4_RS07740 80b1b4c4764b07614a42fab91f76d91e 601 Gene3D G3DSA:3.40.50.300 347 582 4.1E-73 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS07740 80b1b4c4764b07614a42fab91f76d91e 601 Pfam PF00664 ABC transporter transmembrane region 30 295 3.9E-15 T 22-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 L21SP4_RS07740 80b1b4c4764b07614a42fab91f76d91e 601 SUPERFAMILY SSF90123 3 336 2.49E-44 T 22-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 L21SP4_RS07740 80b1b4c4764b07614a42fab91f76d91e 601 PANTHER PTHR24222:SF23 1 601 7.2E-305 T 22-04-2016 L21SP4_RS07740 80b1b4c4764b07614a42fab91f76d91e 601 Pfam PF00005 ABC transporter 368 517 2.9E-27 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 L21SP4_RS07740 80b1b4c4764b07614a42fab91f76d91e 601 SUPERFAMILY SSF52540 341 586 1.47E-84 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS07740 80b1b4c4764b07614a42fab91f76d91e 601 Gene3D G3DSA:1.20.1560.10 4 335 2.2E-38 T 22-04-2016 L21SP4_RS07740 80b1b4c4764b07614a42fab91f76d91e 601 SMART SM00382 377 563 4.2E-16 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS03660 d91e437a72f3fb48e91d89663676c8b8 408 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 274 378 3.0E-20 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS03660 d91e437a72f3fb48e91d89663676c8b8 408 Pfam PF00512 His Kinase A (phospho-acceptor) domain 162 223 1.7E-8 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS03660 d91e437a72f3fb48e91d89663676c8b8 408 PANTHER PTHR24423 4 379 2.8E-71 T 22-04-2016 L21SP4_RS03660 d91e437a72f3fb48e91d89663676c8b8 408 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 34 146 6.6E-14 T 22-04-2016 IPR000014 PAS domain L21SP4_RS03660 d91e437a72f3fb48e91d89663676c8b8 408 Pfam PF00989 PAS fold 35 140 1.3E-11 T 22-04-2016 IPR013767 PAS fold GO:0006355 L21SP4_RS03660 d91e437a72f3fb48e91d89663676c8b8 408 SMART SM00388 158 230 1.8E-8 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS03660 d91e437a72f3fb48e91d89663676c8b8 408 Gene3D G3DSA:3.30.565.10 217 379 2.9E-39 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS03660 d91e437a72f3fb48e91d89663676c8b8 408 SMART SM00387 273 379 3.8E-29 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS03660 d91e437a72f3fb48e91d89663676c8b8 408 PRINTS PR00344 Bacterial sensor protein C-terminal signature 310 324 1.5E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS03660 d91e437a72f3fb48e91d89663676c8b8 408 PRINTS PR00344 Bacterial sensor protein C-terminal signature 363 376 1.5E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS03660 d91e437a72f3fb48e91d89663676c8b8 408 PRINTS PR00344 Bacterial sensor protein C-terminal signature 328 338 1.5E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS03660 d91e437a72f3fb48e91d89663676c8b8 408 PRINTS PR00344 Bacterial sensor protein C-terminal signature 339 357 1.5E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS03660 d91e437a72f3fb48e91d89663676c8b8 408 Gene3D G3DSA:3.30.450.20 29 141 3.9E-16 T 22-04-2016 L21SP4_RS03660 d91e437a72f3fb48e91d89663676c8b8 408 SUPERFAMILY SSF55874 226 377 5.37E-39 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS03660 d91e437a72f3fb48e91d89663676c8b8 408 SUPERFAMILY SSF55785 26 141 3.54E-15 T 22-04-2016 IPR000014 PAS domain L21SP4_RS03660 d91e437a72f3fb48e91d89663676c8b8 408 Gene3D G3DSA:1.10.287.130 153 216 7.5E-9 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS03660 d91e437a72f3fb48e91d89663676c8b8 408 SUPERFAMILY SSF47384 153 228 5.89E-9 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS03660 d91e437a72f3fb48e91d89663676c8b8 408 SMART SM00091 33 98 4.2E-6 T 22-04-2016 IPR000014 PAS domain L21SP4_RS05650 d9727f208d5d75e7ffafe4003b5063b1 317 PANTHER PTHR21071 17 312 8.3E-69 T 22-04-2016 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 L21SP4_RS05650 d9727f208d5d75e7ffafe4003b5063b1 317 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 18 305 6.4E-48 T 22-04-2016 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 L21SP4_RS05650 d9727f208d5d75e7ffafe4003b5063b1 317 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 201 303 4.6E-22 T 22-04-2016 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 L21SP4_RS05650 d9727f208d5d75e7ffafe4003b5063b1 317 SUPERFAMILY SSF56176 18 196 5.61E-28 T 22-04-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 L21SP4_RS05650 d9727f208d5d75e7ffafe4003b5063b1 317 Pfam PF01565 FAD binding domain 36 160 4.6E-13 T 22-04-2016 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 L21SP4_RS05650 d9727f208d5d75e7ffafe4003b5063b1 317 SUPERFAMILY SSF56194 196 309 6.41E-25 T 22-04-2016 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 L21SP4_RS05650 d9727f208d5d75e7ffafe4003b5063b1 317 Gene3D G3DSA:3.30.43.10 17 79 2.7E-10 T 22-04-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 L21SP4_RS05650 d9727f208d5d75e7ffafe4003b5063b1 317 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 317 65.65 T 22-04-2016 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 L21SP4_RS05650 d9727f208d5d75e7ffafe4003b5063b1 317 Gene3D G3DSA:3.90.78.10 218 307 9.1E-23 T 22-04-2016 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 L21SP4_RS05650 d9727f208d5d75e7ffafe4003b5063b1 317 PANTHER PTHR21071:SF4 17 312 8.3E-69 T 22-04-2016 L21SP4_RS05650 d9727f208d5d75e7ffafe4003b5063b1 317 Gene3D G3DSA:3.30.465.10 89 211 9.1E-32 T 22-04-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 L21SP4_RS05135 063ede4769dd7e852c5125a414087818 330 PANTHER PTHR30349:SF5 155 330 6.8E-88 T 22-04-2016 L21SP4_RS05135 063ede4769dd7e852c5125a414087818 330 PANTHER PTHR30349:SF5 17 139 6.8E-88 T 22-04-2016 L21SP4_RS05135 063ede4769dd7e852c5125a414087818 330 Pfam PF00589 Phage integrase family 160 315 5.4E-41 T 22-04-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 L21SP4_RS05135 063ede4769dd7e852c5125a414087818 330 SUPERFAMILY SSF56349 18 322 1.24E-50 T 22-04-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 L21SP4_RS05135 063ede4769dd7e852c5125a414087818 330 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 16 330 33.625 T 22-04-2016 IPR023009 Tyrosine recombinase XerC/XerD L21SP4_RS05135 063ede4769dd7e852c5125a414087818 330 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 20 104 8.8E-15 T 22-04-2016 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 L21SP4_RS05135 063ede4769dd7e852c5125a414087818 330 Gene3D G3DSA:1.10.443.10 127 323 1.6E-53 T 22-04-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 L21SP4_RS05135 063ede4769dd7e852c5125a414087818 330 Gene3D G3DSA:1.10.150.130 17 115 3.6E-20 T 22-04-2016 IPR023109 Integrase/recombinase, N-terminal L21SP4_RS05135 063ede4769dd7e852c5125a414087818 330 PANTHER PTHR30349 155 330 6.8E-88 T 22-04-2016 L21SP4_RS05135 063ede4769dd7e852c5125a414087818 330 PANTHER PTHR30349 17 139 6.8E-88 T 22-04-2016 L21SP4_RS11285 afed526b240d0d5ffe46769c20d83cb6 410 Gene3D G3DSA:3.40.50.2000 224 381 2.3E-24 T 22-04-2016 L21SP4_RS11285 afed526b240d0d5ffe46769c20d83cb6 410 PANTHER PTHR12526 85 408 3.4E-48 T 22-04-2016 L21SP4_RS11285 afed526b240d0d5ffe46769c20d83cb6 410 PANTHER PTHR12526 1 43 3.4E-48 T 22-04-2016 L21SP4_RS11285 afed526b240d0d5ffe46769c20d83cb6 410 Pfam PF13579 Glycosyl transferase 4-like domain 16 213 1.7E-12 T 22-04-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain L21SP4_RS11285 afed526b240d0d5ffe46769c20d83cb6 410 SUPERFAMILY SSF53756 3 74 3.14E-64 T 22-04-2016 L21SP4_RS11285 afed526b240d0d5ffe46769c20d83cb6 410 SUPERFAMILY SSF53756 113 401 3.14E-64 T 22-04-2016 L21SP4_RS11285 afed526b240d0d5ffe46769c20d83cb6 410 Pfam PF00534 Glycosyl transferases group 1 239 381 2.4E-26 T 22-04-2016 IPR001296 Glycosyl transferase, family 1 L21SP4_RS02415 949dd00e0bea937896968d922e7fcfc8 1427 Pfam PF00128 Alpha amylase, catalytic domain 242 341 1.4E-5 T 22-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 L21SP4_RS02415 949dd00e0bea937896968d922e7fcfc8 1427 SUPERFAMILY SSF48208 1342 1423 2.72E-40 T 22-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP4_RS02415 949dd00e0bea937896968d922e7fcfc8 1427 SUPERFAMILY SSF48208 952 1310 2.72E-40 T 22-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP4_RS02415 949dd00e0bea937896968d922e7fcfc8 1427 Pfam PF06202 Amylo-alpha-1,6-glucosidase 1048 1418 1.2E-58 T 22-04-2016 IPR032790 Glycogen debranching enzyme, C-terminal KEGG: 00500+2.4.1.25+3.2.1.33|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 L21SP4_RS02415 949dd00e0bea937896968d922e7fcfc8 1427 Gene3D G3DSA:3.20.20.80 135 495 1.7E-49 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP4_RS02415 949dd00e0bea937896968d922e7fcfc8 1427 SMART SM00642 170 476 4.9E-6 T 22-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 L21SP4_RS02415 949dd00e0bea937896968d922e7fcfc8 1427 PANTHER PTHR10357 176 588 4.9E-32 T 22-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 L21SP4_RS02415 949dd00e0bea937896968d922e7fcfc8 1427 Pfam PF12439 Glycogen debranching enzyme N terminal 792 1000 8.2E-20 T 22-04-2016 IPR024742 Glycogen debranching enzyme, bacterial and archaeal type, N-terminal L21SP4_RS02415 949dd00e0bea937896968d922e7fcfc8 1427 SUPERFAMILY SSF51445 136 498 1.11E-52 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily L21SP4_RS01500 8ddaa8d9a68d6e567707eb28be8550e9 106 SUPERFAMILY SSF52833 2 104 9.42E-38 T 22-04-2016 IPR012336 Thioredoxin-like fold L21SP4_RS01500 8ddaa8d9a68d6e567707eb28be8550e9 106 PRINTS PR00421 Thioredoxin family signature 22 30 4.5E-9 T 22-04-2016 L21SP4_RS01500 8ddaa8d9a68d6e567707eb28be8550e9 106 PRINTS PR00421 Thioredoxin family signature 70 81 4.5E-9 T 22-04-2016 L21SP4_RS01500 8ddaa8d9a68d6e567707eb28be8550e9 106 PRINTS PR00421 Thioredoxin family signature 30 39 4.5E-9 T 22-04-2016 L21SP4_RS01500 8ddaa8d9a68d6e567707eb28be8550e9 106 PANTHER PTHR10438 5 103 3.4E-35 T 22-04-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 L21SP4_RS01500 8ddaa8d9a68d6e567707eb28be8550e9 106 ProSitePatterns PS00194 Thioredoxin family active site. 23 41 - T 22-04-2016 IPR017937 Thioredoxin, conserved site GO:0045454 L21SP4_RS01500 8ddaa8d9a68d6e567707eb28be8550e9 106 Pfam PF00085 Thioredoxin 6 103 6.5E-31 T 22-04-2016 IPR013766 Thioredoxin domain GO:0045454 L21SP4_RS01500 8ddaa8d9a68d6e567707eb28be8550e9 106 PIRSF PIRSF000077 2 106 1.1E-36 T 22-04-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 L21SP4_RS01500 8ddaa8d9a68d6e567707eb28be8550e9 106 TIGRFAM TIGR01068 thioredoxin: thioredoxin 9 104 3.8E-37 T 22-04-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 L21SP4_RS01500 8ddaa8d9a68d6e567707eb28be8550e9 106 Gene3D G3DSA:3.40.30.10 2 104 1.8E-38 T 22-04-2016 IPR012336 Thioredoxin-like fold L21SP4_RS11340 03aff1f7cf53d72c2d61f7d1adc2794f 106 SUPERFAMILY SSF81301 15 97 1.49E-15 T 22-04-2016 L21SP4_RS11340 03aff1f7cf53d72c2d61f7d1adc2794f 106 Gene3D G3DSA:3.30.460.10 10 106 2.1E-23 T 22-04-2016 L21SP4_RS11340 03aff1f7cf53d72c2d61f7d1adc2794f 106 Pfam PF01909 Nucleotidyltransferase domain 18 93 9.4E-11 T 22-04-2016 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 L21SP4_RS10780 0ea3e86fd10754edcefd927b865f0189 494 Pfam PF00884 Sulfatase 23 149 7.9E-22 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS10780 0ea3e86fd10754edcefd927b865f0189 494 Pfam PF00884 Sulfatase 167 315 1.0E-22 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS10780 0ea3e86fd10754edcefd927b865f0189 494 SUPERFAMILY SSF53649 22 376 7.98E-98 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS10780 0ea3e86fd10754edcefd927b865f0189 494 SUPERFAMILY SSF53649 439 484 7.98E-98 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS10780 0ea3e86fd10754edcefd927b865f0189 494 Gene3D G3DSA:3.40.720.10 20 333 8.1E-71 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS10780 0ea3e86fd10754edcefd927b865f0189 494 Gene3D G3DSA:3.30.1120.10 441 487 2.6E-23 T 22-04-2016 L21SP4_RS10780 0ea3e86fd10754edcefd927b865f0189 494 Gene3D G3DSA:3.30.1120.10 347 378 2.6E-23 T 22-04-2016 L21SP4_RS10780 0ea3e86fd10754edcefd927b865f0189 494 PANTHER PTHR10342 1 404 7.2E-93 T 22-04-2016 L21SP4_RS10780 0ea3e86fd10754edcefd927b865f0189 494 PANTHER PTHR10342 435 488 7.2E-93 T 22-04-2016 L21SP4_RS01855 6e65d9f4dc44bee3d476c17a1e77d557 1033 Gene3D G3DSA:2.60.120.260 187 271 4.3E-4 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS01855 6e65d9f4dc44bee3d476c17a1e77d557 1033 SUPERFAMILY SSF48208 580 973 4.49E-26 T 22-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP4_RS01855 6e65d9f4dc44bee3d476c17a1e77d557 1033 SUPERFAMILY SSF49785 187 272 9.69E-5 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS01855 6e65d9f4dc44bee3d476c17a1e77d557 1033 PANTHER PTHR33307 9 139 7.4E-157 T 22-04-2016 L21SP4_RS01855 6e65d9f4dc44bee3d476c17a1e77d557 1033 PANTHER PTHR33307 456 764 7.4E-157 T 22-04-2016 L21SP4_RS01855 6e65d9f4dc44bee3d476c17a1e77d557 1033 PANTHER PTHR33307:SF5 786 983 7.4E-157 T 22-04-2016 L21SP4_RS01855 6e65d9f4dc44bee3d476c17a1e77d557 1033 PANTHER PTHR33307:SF5 9 139 7.4E-157 T 22-04-2016 L21SP4_RS01855 6e65d9f4dc44bee3d476c17a1e77d557 1033 PANTHER PTHR33307:SF5 456 764 7.4E-157 T 22-04-2016 L21SP4_RS01855 6e65d9f4dc44bee3d476c17a1e77d557 1033 Pfam PF05592 Bacterial alpha-L-rhamnosidase 382 970 6.4E-85 T 22-04-2016 IPR008902 Bacterial alpha-L-rhamnosidase L21SP4_RS01855 6e65d9f4dc44bee3d476c17a1e77d557 1033 PANTHER PTHR33307 786 983 7.4E-157 T 22-04-2016 L21SP4_RS01855 6e65d9f4dc44bee3d476c17a1e77d557 1033 PANTHER PTHR33307 176 417 7.4E-157 T 22-04-2016 L21SP4_RS01855 6e65d9f4dc44bee3d476c17a1e77d557 1033 Pfam PF08531 Alpha-L-rhamnosidase N-terminal domain 199 367 5.3E-48 T 22-04-2016 IPR013737 Bacterial alpha-L-rhamnosidase N-terminal L21SP4_RS01855 6e65d9f4dc44bee3d476c17a1e77d557 1033 PANTHER PTHR33307:SF5 176 417 7.4E-157 T 22-04-2016 L21SP4_RS04855 8929b7543a5313803ae6b9a6c97798d9 422 TIGRFAM TIGR00183 prok_nadp_idh: isocitrate dehydrogenase, NADP-dependent 3 420 4.7E-209 T 22-04-2016 IPR004439 Isocitrate dehydrogenase NADP-dependent, dimeric, prokaryotic GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 L21SP4_RS04855 8929b7543a5313803ae6b9a6c97798d9 422 PANTHER PTHR11835:SF52 277 421 4.1E-229 T 22-04-2016 L21SP4_RS04855 8929b7543a5313803ae6b9a6c97798d9 422 PANTHER PTHR11835:SF52 1 166 4.1E-229 T 22-04-2016 L21SP4_RS04855 8929b7543a5313803ae6b9a6c97798d9 422 PANTHER PTHR11835:SF52 190 257 4.1E-229 T 22-04-2016 L21SP4_RS04855 8929b7543a5313803ae6b9a6c97798d9 422 SUPERFAMILY SSF53659 4 420 3.78E-143 T 22-04-2016 L21SP4_RS04855 8929b7543a5313803ae6b9a6c97798d9 422 SMART SM01329 30 416 3.3E-172 T 22-04-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 L21SP4_RS04855 8929b7543a5313803ae6b9a6c97798d9 422 PANTHER PTHR11835 277 421 4.1E-229 T 22-04-2016 IPR001804 Isocitrate and isopropylmalate dehydrogenases family GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: REACT_1046 L21SP4_RS04855 8929b7543a5313803ae6b9a6c97798d9 422 PANTHER PTHR11835 1 166 4.1E-229 T 22-04-2016 IPR001804 Isocitrate and isopropylmalate dehydrogenases family GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: REACT_1046 L21SP4_RS04855 8929b7543a5313803ae6b9a6c97798d9 422 PANTHER PTHR11835 190 257 4.1E-229 T 22-04-2016 IPR001804 Isocitrate and isopropylmalate dehydrogenases family GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: REACT_1046 L21SP4_RS04855 8929b7543a5313803ae6b9a6c97798d9 422 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 31 416 2.3E-112 T 22-04-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 L21SP4_RS04855 8929b7543a5313803ae6b9a6c97798d9 422 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 305 324 - T 22-04-2016 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: REACT_1046 L21SP4_RS04855 8929b7543a5313803ae6b9a6c97798d9 422 Gene3D G3DSA:3.40.718.10 15 420 1.6E-161 T 22-04-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 L21SP4_RS01430 7ee6215f5895f9817a32a4187bd73f93 381 SUPERFAMILY SSF161098 224 364 6.54E-21 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 L21SP4_RS01430 7ee6215f5895f9817a32a4187bd73f93 381 SUPERFAMILY SSF161098 88 152 6.54E-21 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 L21SP4_RS01430 7ee6215f5895f9817a32a4187bd73f93 381 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 102 375 2.0E-17 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 L21SP4_RS01430 7ee6215f5895f9817a32a4187bd73f93 381 PANTHER PTHR30425 222 381 3.8E-96 T 22-04-2016 L21SP4_RS01430 7ee6215f5895f9817a32a4187bd73f93 381 PANTHER PTHR30425 31 155 3.8E-96 T 22-04-2016 L21SP4_RS01430 7ee6215f5895f9817a32a4187bd73f93 381 PANTHER PTHR30425 191 203 3.8E-96 T 22-04-2016 L21SP4_RS01430 7ee6215f5895f9817a32a4187bd73f93 381 PANTHER PTHR30425:SF3 222 381 3.8E-96 T 22-04-2016 L21SP4_RS01430 7ee6215f5895f9817a32a4187bd73f93 381 PANTHER PTHR30425:SF3 31 155 3.8E-96 T 22-04-2016 L21SP4_RS01430 7ee6215f5895f9817a32a4187bd73f93 381 PANTHER PTHR30425:SF3 191 203 3.8E-96 T 22-04-2016 L21SP4_RS01430 7ee6215f5895f9817a32a4187bd73f93 381 Gene3D G3DSA:1.10.3720.10 34 153 3.5E-37 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 L21SP4_RS01430 7ee6215f5895f9817a32a4187bd73f93 381 Gene3D G3DSA:1.10.3720.10 216 377 3.5E-37 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 L21SP4_RS11105 552d86a3ff6debb834e8ea7b49cb9251 329 Gene3D G3DSA:2.60.120.10 240 321 5.3E-10 T 22-04-2016 IPR014710 RmlC-like jelly roll fold L21SP4_RS11105 552d86a3ff6debb834e8ea7b49cb9251 329 PANTHER PTHR18964 10 261 4.2E-49 T 22-04-2016 L21SP4_RS11105 552d86a3ff6debb834e8ea7b49cb9251 329 Gene3D G3DSA:2.60.120.10 4 220 7.2E-68 T 22-04-2016 IPR014710 RmlC-like jelly roll fold L21SP4_RS11105 552d86a3ff6debb834e8ea7b49cb9251 329 SUPERFAMILY SSF51182 4 311 8.22E-80 T 22-04-2016 IPR011051 RmlC-like cupin domain L21SP4_RS11105 552d86a3ff6debb834e8ea7b49cb9251 329 PANTHER PTHR18964:SF114 10 261 4.2E-49 T 22-04-2016 L21SP4_RS11105 552d86a3ff6debb834e8ea7b49cb9251 329 PIRSF PIRSF036894 4 315 4.5E-84 T 22-04-2016 IPR014628 Mannose-6-phosphate isomerase, Firmicutes type, short form GO:0004476|GO:0005975 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 L21SP4_RS11105 552d86a3ff6debb834e8ea7b49cb9251 329 Pfam PF01238 Phosphomannose isomerase type I 8 107 2.4E-15 T 22-04-2016 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 L21SP4_RS10360 a53457d20f109045a592b49f96e30216 432 SUPERFAMILY SSF51984 2 92 6.41E-20 T 22-04-2016 L21SP4_RS10360 a53457d20f109045a592b49f96e30216 432 Gene3D G3DSA:3.40.1190.10 221 281 1.1E-9 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 L21SP4_RS10360 a53457d20f109045a592b49f96e30216 432 Gene3D G3DSA:3.40.1190.10 95 218 2.4E-28 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 L21SP4_RS10360 a53457d20f109045a592b49f96e30216 432 Pfam PF01225 Mur ligase family, catalytic domain 4 104 1.8E-15 T 22-04-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 L21SP4_RS10360 a53457d20f109045a592b49f96e30216 432 PANTHER PTHR23135 1 362 2.6E-78 T 22-04-2016 L21SP4_RS10360 a53457d20f109045a592b49f96e30216 432 Pfam PF08245 Mur ligase middle domain 111 192 5.6E-8 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 L21SP4_RS10360 a53457d20f109045a592b49f96e30216 432 PANTHER PTHR23135:SF5 1 362 2.6E-78 T 22-04-2016 L21SP4_RS10360 a53457d20f109045a592b49f96e30216 432 SUPERFAMILY SSF53623 93 278 7.59E-36 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 L21SP4_RS10360 a53457d20f109045a592b49f96e30216 432 Gene3D G3DSA:3.40.50.720 3 92 2.6E-21 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS10360 a53457d20f109045a592b49f96e30216 432 Pfam PF02875 Mur ligase family, glutamate ligase domain 281 324 3.7E-7 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 L21SP4_RS10360 a53457d20f109045a592b49f96e30216 432 Gene3D G3DSA:3.90.190.20 282 419 1.7E-19 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 L21SP4_RS10360 a53457d20f109045a592b49f96e30216 432 SUPERFAMILY SSF53244 279 420 1.83E-17 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 L21SP4_RS05030 b70e8c6730269ff30f8679ee2c6dd0fc 597 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 5 585 2.8E-192 T 22-04-2016 IPR004524 Aspartate-tRNA ligase, bacterial/mitochondrial-type GO:0005524|GO:0016874 L21SP4_RS05030 b70e8c6730269ff30f8679ee2c6dd0fc 597 SUPERFAMILY SSF50249 4 107 1.56E-29 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold L21SP4_RS05030 b70e8c6730269ff30f8679ee2c6dd0fc 597 Gene3D G3DSA:3.30.1360.30 283 415 1.3E-42 T 22-04-2016 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 L21SP4_RS05030 b70e8c6730269ff30f8679ee2c6dd0fc 597 Pfam PF00152 tRNA synthetases class II (D, K and N) 124 559 1.5E-93 T 22-04-2016 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 L21SP4_RS05030 b70e8c6730269ff30f8679ee2c6dd0fc 597 PANTHER PTHR22594:SF5 2 303 2.2E-204 T 22-04-2016 IPR004524 Aspartate-tRNA ligase, bacterial/mitochondrial-type GO:0005524|GO:0016874 L21SP4_RS05030 b70e8c6730269ff30f8679ee2c6dd0fc 597 PANTHER PTHR22594:SF5 371 573 2.2E-204 T 22-04-2016 IPR004524 Aspartate-tRNA ligase, bacterial/mitochondrial-type GO:0005524|GO:0016874 L21SP4_RS05030 b70e8c6730269ff30f8679ee2c6dd0fc 597 Pfam PF02938 GAD domain 314 404 3.3E-19 T 22-04-2016 IPR029351 GAD domain L21SP4_RS05030 b70e8c6730269ff30f8679ee2c6dd0fc 597 Gene3D G3DSA:3.30.930.10 416 586 9.5E-102 T 22-04-2016 L21SP4_RS05030 b70e8c6730269ff30f8679ee2c6dd0fc 597 Gene3D G3DSA:3.30.930.10 137 282 9.5E-102 T 22-04-2016 L21SP4_RS05030 b70e8c6730269ff30f8679ee2c6dd0fc 597 Gene3D G3DSA:2.40.50.140 4 108 6.5E-35 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold L21SP4_RS05030 b70e8c6730269ff30f8679ee2c6dd0fc 597 Hamap MF_00044 Aspartate--tRNA(Asp) ligase [aspS]. 4 565 33.356 T 22-04-2016 L21SP4_RS05030 b70e8c6730269ff30f8679ee2c6dd0fc 597 SUPERFAMILY SSF55261 295 421 7.85E-35 T 22-04-2016 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 L21SP4_RS05030 b70e8c6730269ff30f8679ee2c6dd0fc 597 Pfam PF01336 OB-fold nucleic acid binding domain 21 104 3.4E-15 T 22-04-2016 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 L21SP4_RS05030 b70e8c6730269ff30f8679ee2c6dd0fc 597 SUPERFAMILY SSF55681 426 586 1.99E-94 T 22-04-2016 L21SP4_RS05030 b70e8c6730269ff30f8679ee2c6dd0fc 597 SUPERFAMILY SSF55681 118 298 1.99E-94 T 22-04-2016 L21SP4_RS05030 b70e8c6730269ff30f8679ee2c6dd0fc 597 PANTHER PTHR22594 2 303 2.2E-204 T 22-04-2016 IPR018150 Aminoacyl-tRNA synthetase, class II (D/K/N)-like GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 L21SP4_RS05030 b70e8c6730269ff30f8679ee2c6dd0fc 597 PANTHER PTHR22594 371 573 2.2E-204 T 22-04-2016 IPR018150 Aminoacyl-tRNA synthetase, class II (D/K/N)-like GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 L21SP4_RS05030 b70e8c6730269ff30f8679ee2c6dd0fc 597 PRINTS PR01042 Aspartyl-tRNA synthetase signature 476 492 2.6E-20 T 22-04-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 L21SP4_RS05030 b70e8c6730269ff30f8679ee2c6dd0fc 597 PRINTS PR01042 Aspartyl-tRNA synthetase signature 194 206 2.6E-20 T 22-04-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 L21SP4_RS05030 b70e8c6730269ff30f8679ee2c6dd0fc 597 PRINTS PR01042 Aspartyl-tRNA synthetase signature 520 534 2.6E-20 T 22-04-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 L21SP4_RS05030 b70e8c6730269ff30f8679ee2c6dd0fc 597 PRINTS PR01042 Aspartyl-tRNA synthetase signature 211 224 2.6E-20 T 22-04-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 L21SP4_RS09095 62371fb38a45da905df095da7b58dbc9 491 SUPERFAMILY SSF102114 57 371 3.27E-49 T 22-04-2016 L21SP4_RS09095 62371fb38a45da905df095da7b58dbc9 491 SMART SM00876 290 400 2.3E-21 T 22-04-2016 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380|UniPathway: UPA00078 L21SP4_RS09095 62371fb38a45da905df095da7b58dbc9 491 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 290 398 9.1E-17 T 22-04-2016 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380|UniPathway: UPA00078 L21SP4_RS09095 62371fb38a45da905df095da7b58dbc9 491 TIGRFAM TIGR03955 rSAM_HydG: [FeFe] hydrogenase H-cluster radical SAM maturase HydG 22 490 5.3E-134 T 22-04-2016 IPR024007 [FeFe]-hydrogenase maturation HydG, radical SAM L21SP4_RS09095 62371fb38a45da905df095da7b58dbc9 491 PANTHER PTHR22976:SF2 16 434 4.9E-206 T 22-04-2016 L21SP4_RS09095 62371fb38a45da905df095da7b58dbc9 491 PANTHER PTHR22976 16 434 4.9E-206 T 22-04-2016 L21SP4_RS09095 62371fb38a45da905df095da7b58dbc9 491 Gene3D G3DSA:3.20.20.70 57 353 1.5E-47 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP4_RS11975 63f54c409b4286a9ffba6beb0bee8ff7 1463 PANTHER PTHR23083 1034 1137 4.3E-38 T 22-04-2016 L21SP4_RS11975 63f54c409b4286a9ffba6beb0bee8ff7 1463 PANTHER PTHR23083 722 824 4.3E-38 T 22-04-2016 L21SP4_RS11975 63f54c409b4286a9ffba6beb0bee8ff7 1463 PANTHER PTHR23083 1342 1444 4.3E-38 T 22-04-2016 L21SP4_RS11975 63f54c409b4286a9ffba6beb0bee8ff7 1463 PANTHER PTHR23083 33 70 4.3E-38 T 22-04-2016 L21SP4_RS11975 63f54c409b4286a9ffba6beb0bee8ff7 1463 PANTHER PTHR23083 979 1017 4.3E-38 T 22-04-2016 L21SP4_RS11975 63f54c409b4286a9ffba6beb0bee8ff7 1463 PANTHER PTHR23083 454 518 4.3E-38 T 22-04-2016 L21SP4_RS11975 63f54c409b4286a9ffba6beb0bee8ff7 1463 SMART SM00386 1046 1078 97.0 T 22-04-2016 IPR003107 HAT (Half-A-TPR) repeat GO:0006396 L21SP4_RS11975 63f54c409b4286a9ffba6beb0bee8ff7 1463 SMART SM00386 499 531 1200.0 T 22-04-2016 IPR003107 HAT (Half-A-TPR) repeat GO:0006396 L21SP4_RS11975 63f54c409b4286a9ffba6beb0bee8ff7 1463 SMART SM00386 774 807 190.0 T 22-04-2016 IPR003107 HAT (Half-A-TPR) repeat GO:0006396 L21SP4_RS11975 63f54c409b4286a9ffba6beb0bee8ff7 1463 SMART SM00386 740 772 3.8 T 22-04-2016 IPR003107 HAT (Half-A-TPR) repeat GO:0006396 L21SP4_RS11975 63f54c409b4286a9ffba6beb0bee8ff7 1463 SMART SM00386 1357 1389 1200.0 T 22-04-2016 IPR003107 HAT (Half-A-TPR) repeat GO:0006396 L21SP4_RS11975 63f54c409b4286a9ffba6beb0bee8ff7 1463 SMART SM00386 46 78 130.0 T 22-04-2016 IPR003107 HAT (Half-A-TPR) repeat GO:0006396 L21SP4_RS11975 63f54c409b4286a9ffba6beb0bee8ff7 1463 Gene3D G3DSA:1.25.40.10 903 1100 3.4E-13 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS11975 63f54c409b4286a9ffba6beb0bee8ff7 1463 Gene3D G3DSA:1.25.40.10 1225 1448 1.5E-16 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS11975 63f54c409b4286a9ffba6beb0bee8ff7 1463 Gene3D G3DSA:1.25.40.10 421 518 1.8E-14 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS11975 63f54c409b4286a9ffba6beb0bee8ff7 1463 Gene3D G3DSA:1.25.40.10 201 329 1.8E-14 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS11975 63f54c409b4286a9ffba6beb0bee8ff7 1463 Gene3D G3DSA:1.25.40.10 687 883 5.4E-22 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS11975 63f54c409b4286a9ffba6beb0bee8ff7 1463 Gene3D G3DSA:1.25.40.10 28 106 1.8E-14 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS11975 63f54c409b4286a9ffba6beb0bee8ff7 1463 SUPERFAMILY SSF48452 1303 1411 1.46E-11 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS11975 63f54c409b4286a9ffba6beb0bee8ff7 1463 SMART SM00028 1343 1376 310.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS11975 63f54c409b4286a9ffba6beb0bee8ff7 1463 SMART SM00028 1066 1102 150.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS11975 63f54c409b4286a9ffba6beb0bee8ff7 1463 SMART SM00028 760 793 0.015 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS11975 63f54c409b4286a9ffba6beb0bee8ff7 1463 SMART SM00028 726 759 490.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS11975 63f54c409b4286a9ffba6beb0bee8ff7 1463 SMART SM00028 1032 1065 54.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS11975 63f54c409b4286a9ffba6beb0bee8ff7 1463 SMART SM00028 485 518 310.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS11975 63f54c409b4286a9ffba6beb0bee8ff7 1463 SMART SM00028 32 65 6.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS11975 63f54c409b4286a9ffba6beb0bee8ff7 1463 SMART SM00028 1416 1449 34.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS11975 63f54c409b4286a9ffba6beb0bee8ff7 1463 SUPERFAMILY SSF48452 1032 1204 2.09E-16 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS11975 63f54c409b4286a9ffba6beb0bee8ff7 1463 Pfam PF14559 Tetratricopeptide repeat 1317 1381 1.2E-5 T 22-04-2016 L21SP4_RS11975 63f54c409b4286a9ffba6beb0bee8ff7 1463 Pfam PF13432 Tetratricopeptide repeat 1006 1063 0.0017 T 22-04-2016 L21SP4_RS11975 63f54c409b4286a9ffba6beb0bee8ff7 1463 Pfam PF13432 Tetratricopeptide repeat 732 792 6.5E-7 T 22-04-2016 L21SP4_RS11975 63f54c409b4286a9ffba6beb0bee8ff7 1463 Pfam PF13432 Tetratricopeptide repeat 1120 1172 0.0012 T 22-04-2016 L21SP4_RS11975 63f54c409b4286a9ffba6beb0bee8ff7 1463 Pfam PF13432 Tetratricopeptide repeat 30 66 0.01 T 22-04-2016 L21SP4_RS11975 63f54c409b4286a9ffba6beb0bee8ff7 1463 SUPERFAMILY SSF48452 724 885 5.42E-20 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS11975 63f54c409b4286a9ffba6beb0bee8ff7 1463 Gene3D G3DSA:1.25.40.10 1101 1201 3.3E-11 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS11975 63f54c409b4286a9ffba6beb0bee8ff7 1463 SUPERFAMILY SSF48452 31 67 8.04E-8 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS11975 63f54c409b4286a9ffba6beb0bee8ff7 1463 SUPERFAMILY SSF48452 416 580 8.04E-8 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS06205 ed400de1c16f0bd92a01ed1c313b4c2c 353 Gene3D G3DSA:3.20.20.70 82 328 3.5E-14 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP4_RS06205 ed400de1c16f0bd92a01ed1c313b4c2c 353 PANTHER PTHR30538:SF1 36 315 1.8E-96 T 22-04-2016 L21SP4_RS06205 ed400de1c16f0bd92a01ed1c313b4c2c 353 SUPERFAMILY SSF102114 83 319 1.83E-22 T 22-04-2016 L21SP4_RS06205 ed400de1c16f0bd92a01ed1c313b4c2c 353 Pfam PF12544 Lysine-2,3-aminomutase 287 335 6.4E-10 T 22-04-2016 IPR025895 Lysine-2,3-aminomutase, C-terminal domain L21SP4_RS06205 ed400de1c16f0bd92a01ed1c313b4c2c 353 PIRSF PIRSF004911 3 352 2.6E-112 T 22-04-2016 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase L21SP4_RS06205 ed400de1c16f0bd92a01ed1c313b4c2c 353 TIGRFAM TIGR00238 TIGR00238: KamA family protein 28 308 2.4E-67 T 22-04-2016 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase L21SP4_RS06205 ed400de1c16f0bd92a01ed1c313b4c2c 353 PANTHER PTHR30538 36 315 1.8E-96 T 22-04-2016 L21SP4_RS04015 e20327d9129fa9a82bc79630e0ad569a 292 Pfam PF01937 Protein of unknown function DUF89 3 275 8.8E-52 T 22-04-2016 IPR002791 Domain of unknown function DUF89 L21SP4_RS04015 e20327d9129fa9a82bc79630e0ad569a 292 PIRSF PIRSF006593 1 287 1.5E-82 T 22-04-2016 IPR014444 Uncharacterised conserved protein UCP006593 L21SP4_RS04015 e20327d9129fa9a82bc79630e0ad569a 292 SUPERFAMILY SSF111321 1 282 1.7E-76 T 22-04-2016 IPR002791 Domain of unknown function DUF89 L21SP4_RS00805 e49da653c2707a0359aba478c12fa96b 1090 Pfam PF00270 DEAD/DEAH box helicase 560 719 3.1E-18 T 22-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 L21SP4_RS00805 e49da653c2707a0359aba478c12fa96b 1090 Gene3D G3DSA:3.40.50.300 543 741 2.8E-54 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS00805 e49da653c2707a0359aba478c12fa96b 1090 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 379 1042 1.8E-273 T 22-04-2016 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 L21SP4_RS00805 e49da653c2707a0359aba478c12fa96b 1090 Pfam PF02559 CarD-like/TRCF domain 436 529 9.5E-25 T 22-04-2016 IPR003711 CarD-like/TRCF domain L21SP4_RS00805 e49da653c2707a0359aba478c12fa96b 1090 PANTHER PTHR14025 335 1055 0.0 T 22-04-2016 L21SP4_RS00805 e49da653c2707a0359aba478c12fa96b 1090 SMART SM00490 781 865 2.5E-16 T 22-04-2016 IPR001650 Helicase, C-terminal L21SP4_RS00805 e49da653c2707a0359aba478c12fa96b 1090 Pfam PF03461 TRCF domain 976 1055 4.2E-18 T 22-04-2016 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 L21SP4_RS00805 e49da653c2707a0359aba478c12fa96b 1090 SUPERFAMILY SSF52540 478 738 4.27E-58 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS00805 e49da653c2707a0359aba478c12fa96b 1090 SMART SM00487 555 744 1.2E-32 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain L21SP4_RS00805 e49da653c2707a0359aba478c12fa96b 1090 SMART SM01058 434 531 1.0E-31 T 22-04-2016 IPR003711 CarD-like/TRCF domain L21SP4_RS00805 e49da653c2707a0359aba478c12fa96b 1090 SUPERFAMILY SSF143517 976 1061 2.48E-20 T 22-04-2016 L21SP4_RS00805 e49da653c2707a0359aba478c12fa96b 1090 PANTHER PTHR14025:SF21 335 1055 0.0 T 22-04-2016 L21SP4_RS00805 e49da653c2707a0359aba478c12fa96b 1090 SMART SM00982 976 1067 9.3E-16 T 22-04-2016 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 L21SP4_RS00805 e49da653c2707a0359aba478c12fa96b 1090 Pfam PF00271 Helicase conserved C-terminal domain 762 864 7.0E-16 T 22-04-2016 IPR001650 Helicase, C-terminal L21SP4_RS00805 e49da653c2707a0359aba478c12fa96b 1090 SUPERFAMILY SSF141259 427 503 3.53E-20 T 22-04-2016 IPR003711 CarD-like/TRCF domain L21SP4_RS00805 e49da653c2707a0359aba478c12fa96b 1090 Gene3D G3DSA:3.30.2060.10 146 222 7.2E-12 T 22-04-2016 L21SP4_RS00805 e49da653c2707a0359aba478c12fa96b 1090 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 15 1054 26.831 T 22-04-2016 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 L21SP4_RS00805 e49da653c2707a0359aba478c12fa96b 1090 SUPERFAMILY SSF52540 737 943 1.45E-40 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS00805 e49da653c2707a0359aba478c12fa96b 1090 SUPERFAMILY SSF52540 18 258 5.13E-47 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS00805 e49da653c2707a0359aba478c12fa96b 1090 Gene3D G3DSA:3.40.50.300 748 918 2.0E-30 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS04105 b1020f3dee857bb2319e3f500a347d00 290 PANTHER PTHR20275 55 285 4.3E-73 T 22-04-2016 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 L21SP4_RS04105 b1020f3dee857bb2319e3f500a347d00 290 Pfam PF01513 ATP-NAD kinase 58 269 9.5E-51 T 22-04-2016 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 L21SP4_RS04105 b1020f3dee857bb2319e3f500a347d00 290 SUPERFAMILY SSF111331 5 286 4.58E-73 T 22-04-2016 IPR016064 NAD kinase/diacylglycerol kinase-like domain L21SP4_RS04105 b1020f3dee857bb2319e3f500a347d00 290 Hamap MF_00361 NAD kinase [nadK]. 4 285 29.395 T 22-04-2016 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 L21SP4_RS04105 b1020f3dee857bb2319e3f500a347d00 290 Gene3D G3DSA:3.40.50.10330 2 147 2.0E-31 T 22-04-2016 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 L21SP4_RS04105 b1020f3dee857bb2319e3f500a347d00 290 Gene3D G3DSA:2.60.200.30 148 261 4.1E-40 T 22-04-2016 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 L21SP4_RS05245 38903f85a22cea8bf47370990c4c42e9 63 PANTHER PTHR37304 1 61 1.4E-22 T 22-04-2016 L21SP4_RS05245 38903f85a22cea8bf47370990c4c42e9 63 PANTHER PTHR37304:SF1 1 61 1.4E-22 T 22-04-2016 L21SP4_RS05245 38903f85a22cea8bf47370990c4c42e9 63 Pfam PF04070 Domain of unknown function (DUF378) 2 60 6.6E-25 T 22-04-2016 IPR007211 Protein of unknown function DUF378 L21SP4_RS06050 f2716735cf6c8671998aa4d35b338653 401 SUPERFAMILY SSF53613 7 353 2.96E-39 T 22-04-2016 IPR029056 Ribokinase-like L21SP4_RS06050 f2716735cf6c8671998aa4d35b338653 401 Pfam PF00294 pfkB family carbohydrate kinase 38 354 2.5E-20 T 22-04-2016 IPR011611 Carbohydrate kinase PfkB L21SP4_RS06050 f2716735cf6c8671998aa4d35b338653 401 PANTHER PTHR10584 241 272 2.4E-27 T 22-04-2016 L21SP4_RS06050 f2716735cf6c8671998aa4d35b338653 401 PANTHER PTHR10584 293 359 2.4E-27 T 22-04-2016 L21SP4_RS06050 f2716735cf6c8671998aa4d35b338653 401 PANTHER PTHR10584 35 224 2.4E-27 T 22-04-2016 L21SP4_RS06050 f2716735cf6c8671998aa4d35b338653 401 Gene3D G3DSA:3.40.1190.20 6 369 7.4E-45 T 22-04-2016 IPR029056 Ribokinase-like L21SP4_RS06665 51ba2818d0ddc64094440c76ea0bdc0c 354 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 2 349 40.864 T 22-04-2016 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 L21SP4_RS06665 51ba2818d0ddc64094440c76ea0bdc0c 354 Gene3D G3DSA:3.40.50.1100 59 132 1.5E-16 T 22-04-2016 L21SP4_RS06665 51ba2818d0ddc64094440c76ea0bdc0c 354 PANTHER PTHR10314:SF3 15 349 1.2E-157 T 22-04-2016 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 L21SP4_RS06665 51ba2818d0ddc64094440c76ea0bdc0c 354 PIRSF PIRSF001413 3 352 3.0E-136 T 22-04-2016 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 L21SP4_RS06665 51ba2818d0ddc64094440c76ea0bdc0c 354 PANTHER PTHR10314 15 349 1.2E-157 T 22-04-2016 L21SP4_RS06665 51ba2818d0ddc64094440c76ea0bdc0c 354 Gene3D G3DSA:3.40.50.1100 133 348 1.7E-78 T 22-04-2016 L21SP4_RS06665 51ba2818d0ddc64094440c76ea0bdc0c 354 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 15 336 6.8E-44 T 22-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme L21SP4_RS06665 51ba2818d0ddc64094440c76ea0bdc0c 354 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 41 55 - T 22-04-2016 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 L21SP4_RS06665 51ba2818d0ddc64094440c76ea0bdc0c 354 SUPERFAMILY SSF53686 13 347 1.83E-119 T 22-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme L21SP4_RS06665 51ba2818d0ddc64094440c76ea0bdc0c 354 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 13 347 6.1E-144 T 22-04-2016 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 L21SP4_RS00825 ce0f0b3d7334df48289d99ddfe85f198 311 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 1 305 32.549 T 22-04-2016 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 L21SP4_RS00825 ce0f0b3d7334df48289d99ddfe85f198 311 Pfam PF00551 Formyl transferase 1 177 1.0E-37 T 22-04-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 L21SP4_RS00825 ce0f0b3d7334df48289d99ddfe85f198 311 Gene3D G3DSA:3.40.50.170 1 205 1.9E-65 T 22-04-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 L21SP4_RS00825 ce0f0b3d7334df48289d99ddfe85f198 311 Gene3D G3DSA:3.10.25.10 207 309 1.2E-30 T 22-04-2016 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 L21SP4_RS00825 ce0f0b3d7334df48289d99ddfe85f198 311 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 1 303 6.4E-83 T 22-04-2016 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 L21SP4_RS00825 ce0f0b3d7334df48289d99ddfe85f198 311 Pfam PF02911 Formyl transferase, C-terminal domain 204 302 8.3E-28 T 22-04-2016 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 L21SP4_RS00825 ce0f0b3d7334df48289d99ddfe85f198 311 SUPERFAMILY SSF53328 1 206 9.94E-60 T 22-04-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 L21SP4_RS00825 ce0f0b3d7334df48289d99ddfe85f198 311 PANTHER PTHR11138 1 311 7.1E-102 T 22-04-2016 L21SP4_RS00825 ce0f0b3d7334df48289d99ddfe85f198 311 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 133 156 - T 22-04-2016 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 L21SP4_RS00825 ce0f0b3d7334df48289d99ddfe85f198 311 SUPERFAMILY SSF50486 205 309 7.38E-30 T 22-04-2016 IPR011034 Formyl transferase, C-terminal-like GO:0003824 L21SP4_RS07410 5d5588e8315d484e60c8b6a168942308 85 SUPERFAMILY SSF143120 1 74 4.71E-15 T 22-04-2016 L21SP4_RS07410 5d5588e8315d484e60c8b6a168942308 85 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 5 56 8.0E-11 T 22-04-2016 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM L21SP4_RS07410 5d5588e8315d484e60c8b6a168942308 85 PANTHER PTHR33713 1 84 1.9E-45 T 22-04-2016 L21SP4_RS07410 5d5588e8315d484e60c8b6a168942308 85 Gene3D G3DSA:3.40.1620.10 17 49 5.4E-7 T 22-04-2016 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM L21SP4_RS07410 5d5588e8315d484e60c8b6a168942308 85 PANTHER PTHR33713:SF3 1 84 1.9E-45 T 22-04-2016 L21SP4_RS07410 5d5588e8315d484e60c8b6a168942308 85 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 72 1.8E-14 T 22-04-2016 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM L21SP4_RS10185 d39235ec7db83aebf04ccb355773c4f8 277 Pfam PF01867 CRISPR associated protein Cas1 136 242 2.1E-8 T 22-04-2016 IPR002729 CRISPR-associated protein Cas1 L21SP4_RS10185 d39235ec7db83aebf04ccb355773c4f8 277 Pfam PF01867 CRISPR associated protein Cas1 25 127 3.3E-7 T 22-04-2016 IPR002729 CRISPR-associated protein Cas1 L21SP4_RS10185 d39235ec7db83aebf04ccb355773c4f8 277 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 11 275 10.72 T 22-04-2016 IPR002729 CRISPR-associated protein Cas1 L21SP4_RS10185 d39235ec7db83aebf04ccb355773c4f8 277 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 136 243 5.3E-24 T 22-04-2016 IPR002729 CRISPR-associated protein Cas1 L21SP4_RS10185 d39235ec7db83aebf04ccb355773c4f8 277 TIGRFAM TIGR03638 cas1_ECOLI: CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI 11 276 2.7E-89 T 22-04-2016 IPR019851 CRISPR-associated protein Cas1, ECOLI subtype L21SP4_RS02410 92c5db555d466e9aeea393e1714b7370 275 PANTHER PTHR22594 1 261 2.8E-90 T 22-04-2016 IPR018150 Aminoacyl-tRNA synthetase, class II (D/K/N)-like GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 L21SP4_RS02410 92c5db555d466e9aeea393e1714b7370 275 Gene3D G3DSA:3.30.930.10 1 270 1.1E-51 T 22-04-2016 L21SP4_RS02410 92c5db555d466e9aeea393e1714b7370 275 PANTHER PTHR22594:SF7 1 261 2.8E-90 T 22-04-2016 IPR004525 Elongation factor P--(R)-beta-lysine ligase GO:0004824|GO:0005524|GO:0005737|GO:0006430 L21SP4_RS02410 92c5db555d466e9aeea393e1714b7370 275 Pfam PF00152 tRNA synthetases class II (D, K and N) 2 262 4.5E-30 T 22-04-2016 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 L21SP4_RS02410 92c5db555d466e9aeea393e1714b7370 275 SUPERFAMILY SSF55681 1 261 4.76E-62 T 22-04-2016 L21SP4_RS03100 d0e1c00399b047e5354ad75691e2e2c0 187 PANTHER PTHR23416 82 180 4.1E-12 T 22-04-2016 L21SP4_RS03100 d0e1c00399b047e5354ad75691e2e2c0 187 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 134 167 3.5E-13 T 22-04-2016 IPR001451 Hexapeptide repeat L21SP4_RS03100 d0e1c00399b047e5354ad75691e2e2c0 187 SUPERFAMILY SSF51161 68 182 3.88E-23 T 22-04-2016 IPR011004 Trimeric LpxA-like L21SP4_RS03100 d0e1c00399b047e5354ad75691e2e2c0 187 Gene3D G3DSA:2.160.10.10 69 182 1.6E-22 T 22-04-2016 L21SP4_RS10000 1a8b554ee001e97831dfdccf85a68c24 110 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 1 108 15.71 T 22-04-2016 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 L21SP4_RS10000 1a8b554ee001e97831dfdccf85a68c24 110 PANTHER PTHR28259 1 107 9.4E-25 T 22-04-2016 L21SP4_RS10000 1a8b554ee001e97831dfdccf85a68c24 110 TIGRFAM TIGR00494 crcB: protein CrcB 1 105 4.6E-25 T 22-04-2016 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 L21SP4_RS10000 1a8b554ee001e97831dfdccf85a68c24 110 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 1 103 2.3E-18 T 22-04-2016 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 L21SP4_RS07965 9e5123ab4591b21cf686ad2109163326 158 SUPERFAMILY SSF55068 6 155 2.62E-70 T 22-04-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 L21SP4_RS07965 9e5123ab4591b21cf686ad2109163326 158 PANTHER PTHR10173 8 158 3.9E-82 T 22-04-2016 IPR028427 Peptide methionine sulfoxide reductase GO:0006979|GO:0016671|GO:0030091 L21SP4_RS07965 9e5123ab4591b21cf686ad2109163326 158 PANTHER PTHR10173:SF6 8 158 3.9E-82 T 22-04-2016 L21SP4_RS07965 9e5123ab4591b21cf686ad2109163326 158 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 6 158 34.798 T 22-04-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 L21SP4_RS07965 9e5123ab4591b21cf686ad2109163326 158 Pfam PF01625 Peptide methionine sulfoxide reductase 9 155 4.5E-64 T 22-04-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 L21SP4_RS07965 9e5123ab4591b21cf686ad2109163326 158 Gene3D G3DSA:3.30.1060.10 7 155 3.0E-72 T 22-04-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 L21SP4_RS07965 9e5123ab4591b21cf686ad2109163326 158 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 8 152 6.7E-63 T 22-04-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 L21SP4_RS03670 9e3483ce212413d47f279f3da20d3300 477 Pfam PF13365 Trypsin-like peptidase domain 101 235 1.9E-33 T 22-04-2016 L21SP4_RS03670 9e3483ce212413d47f279f3da20d3300 477 Gene3D G3DSA:2.40.10.10 34 165 2.3E-33 T 22-04-2016 L21SP4_RS03670 9e3483ce212413d47f279f3da20d3300 477 Pfam PF13180 PDZ domain 275 365 2.6E-17 T 22-04-2016 IPR001478 PDZ domain GO:0005515 L21SP4_RS03670 9e3483ce212413d47f279f3da20d3300 477 SUPERFAMILY SSF50156 232 356 4.73E-26 T 22-04-2016 IPR001478 PDZ domain GO:0005515 L21SP4_RS03670 9e3483ce212413d47f279f3da20d3300 477 PANTHER PTHR22939:SF79 83 404 1.3E-122 T 22-04-2016 L21SP4_RS03670 9e3483ce212413d47f279f3da20d3300 477 PANTHER PTHR22939:SF79 21 61 1.3E-122 T 22-04-2016 L21SP4_RS03670 9e3483ce212413d47f279f3da20d3300 477 PRINTS PR00834 HtrA/DegQ protease family signature 110 122 3.5E-55 T 22-04-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 L21SP4_RS03670 9e3483ce212413d47f279f3da20d3300 477 PRINTS PR00834 HtrA/DegQ protease family signature 131 151 3.5E-55 T 22-04-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 L21SP4_RS03670 9e3483ce212413d47f279f3da20d3300 477 PRINTS PR00834 HtrA/DegQ protease family signature 314 326 3.5E-55 T 22-04-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 L21SP4_RS03670 9e3483ce212413d47f279f3da20d3300 477 PRINTS PR00834 HtrA/DegQ protease family signature 206 223 3.5E-55 T 22-04-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 L21SP4_RS03670 9e3483ce212413d47f279f3da20d3300 477 PRINTS PR00834 HtrA/DegQ protease family signature 171 195 3.5E-55 T 22-04-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 L21SP4_RS03670 9e3483ce212413d47f279f3da20d3300 477 PRINTS PR00834 HtrA/DegQ protease family signature 228 245 3.5E-55 T 22-04-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 L21SP4_RS03670 9e3483ce212413d47f279f3da20d3300 477 PANTHER PTHR22939 83 404 1.3E-122 T 22-04-2016 L21SP4_RS03670 9e3483ce212413d47f279f3da20d3300 477 PANTHER PTHR22939 21 61 1.3E-122 T 22-04-2016 L21SP4_RS03670 9e3483ce212413d47f279f3da20d3300 477 SMART SM00228 274 356 2.9E-14 T 22-04-2016 IPR001478 PDZ domain GO:0005515 L21SP4_RS03670 9e3483ce212413d47f279f3da20d3300 477 SMART SM00228 383 465 3.4E-9 T 22-04-2016 IPR001478 PDZ domain GO:0005515 L21SP4_RS03670 9e3483ce212413d47f279f3da20d3300 477 Gene3D G3DSA:2.40.10.10 166 275 1.9E-45 T 22-04-2016 L21SP4_RS03670 9e3483ce212413d47f279f3da20d3300 477 SUPERFAMILY SSF50156 385 475 1.17E-14 T 22-04-2016 IPR001478 PDZ domain GO:0005515 L21SP4_RS03670 9e3483ce212413d47f279f3da20d3300 477 SUPERFAMILY SSF50494 41 62 6.34E-64 T 22-04-2016 IPR009003 Peptidase S1, PA clan L21SP4_RS03670 9e3483ce212413d47f279f3da20d3300 477 SUPERFAMILY SSF50494 89 270 6.34E-64 T 22-04-2016 IPR009003 Peptidase S1, PA clan L21SP4_RS03670 9e3483ce212413d47f279f3da20d3300 477 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 40 465 7.6E-157 T 22-04-2016 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 L21SP4_RS03670 9e3483ce212413d47f279f3da20d3300 477 Gene3D G3DSA:2.30.42.10 385 476 4.7E-17 T 22-04-2016 IPR001478 PDZ domain GO:0005515 L21SP4_RS03670 9e3483ce212413d47f279f3da20d3300 477 Gene3D G3DSA:2.30.42.10 276 372 5.3E-30 T 22-04-2016 IPR001478 PDZ domain GO:0005515 L21SP4_RS10750 9c729ffd54cd3838ed52d9605de14ea4 464 Pfam PF05592 Bacterial alpha-L-rhamnosidase 5 434 6.4E-98 T 22-04-2016 IPR008902 Bacterial alpha-L-rhamnosidase L21SP4_RS10750 9c729ffd54cd3838ed52d9605de14ea4 464 PANTHER PTHR33307 5 445 2.3E-103 T 22-04-2016 L21SP4_RS10750 9c729ffd54cd3838ed52d9605de14ea4 464 PANTHER PTHR33307:SF5 5 445 2.3E-103 T 22-04-2016 L21SP4_RS10750 9c729ffd54cd3838ed52d9605de14ea4 464 SUPERFAMILY SSF48208 112 435 2.77E-40 T 22-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP4_RS10750 9c729ffd54cd3838ed52d9605de14ea4 464 Gene3D G3DSA:1.50.10.10 194 252 8.0E-5 T 22-04-2016 IPR012341 Six-hairpin glycosidase GO:0003824 L21SP4_RS09030 5da81a7b81d22496bffc3b5211fc1e22 240 PANTHER PTHR10859 13 223 3.2E-45 T 22-04-2016 L21SP4_RS09030 5da81a7b81d22496bffc3b5211fc1e22 240 SUPERFAMILY SSF53448 9 210 2.59E-33 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases L21SP4_RS09030 5da81a7b81d22496bffc3b5211fc1e22 240 Pfam PF00535 Glycosyl transferase family 2 12 165 9.4E-23 T 22-04-2016 IPR001173 Glycosyltransferase 2-like L21SP4_RS09030 5da81a7b81d22496bffc3b5211fc1e22 240 Gene3D G3DSA:3.90.550.10 13 204 1.4E-11 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases L21SP4_RS09030 5da81a7b81d22496bffc3b5211fc1e22 240 PANTHER PTHR10859:SF84 13 223 3.2E-45 T 22-04-2016 L21SP4_RS05940 f8e5fd5cee16fa611ea9ddc65716edff 537 PANTHER PTHR11819 2 509 2.3E-156 T 22-04-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 L21SP4_RS05940 f8e5fd5cee16fa611ea9ddc65716edff 537 PANTHER PTHR11819:SF157 2 509 2.3E-156 T 22-04-2016 L21SP4_RS05940 f8e5fd5cee16fa611ea9ddc65716edff 537 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 414 434 - T 22-04-2016 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 L21SP4_RS05940 f8e5fd5cee16fa611ea9ddc65716edff 537 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 38 432 7.9E-110 T 22-04-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 L21SP4_RS05940 f8e5fd5cee16fa611ea9ddc65716edff 537 Pfam PF00474 Sodium:solute symporter family 38 432 7.0E-86 T 22-04-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 L21SP4_RS01625 2d96f11ca19d0ff596ff74f9a676c21c 155 Gene3D G3DSA:3.40.140.10 2 149 4.4E-49 T 22-04-2016 L21SP4_RS01625 2d96f11ca19d0ff596ff74f9a676c21c 155 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 52 89 - T 22-04-2016 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 L21SP4_RS01625 2d96f11ca19d0ff596ff74f9a676c21c 155 SUPERFAMILY SSF53927 2 149 1.47E-45 T 22-04-2016 IPR016193 Cytidine deaminase-like GO:0003824 L21SP4_RS01625 2d96f11ca19d0ff596ff74f9a676c21c 155 PANTHER PTHR11079:SF25 1 155 2.7E-48 T 22-04-2016 L21SP4_RS01625 2d96f11ca19d0ff596ff74f9a676c21c 155 PANTHER PTHR11079 1 155 2.7E-48 T 22-04-2016 L21SP4_RS01625 2d96f11ca19d0ff596ff74f9a676c21c 155 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 3 100 4.6E-25 T 22-04-2016 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 L21SP4_RS07325 a5b947a8d4d5facf58927a2bc842cc56 226 Pfam PF02517 CAAX protease self-immunity 129 218 4.7E-12 T 22-04-2016 IPR003675 CAAX amino terminal protease GO:0016020 L21SP4_RS02325 6827269fb8fd9f9f6942991108efb49c 190 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 190 21.722 T 22-04-2016 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|UniPathway: UPA00070 L21SP4_RS02325 6827269fb8fd9f9f6942991108efb49c 190 PANTHER PTHR19278 11 163 3.6E-25 T 22-04-2016 L21SP4_RS02325 6827269fb8fd9f9f6942991108efb49c 190 SUPERFAMILY SSF53271 10 178 2.7E-30 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like L21SP4_RS02325 6827269fb8fd9f9f6942991108efb49c 190 Pfam PF00156 Phosphoribosyl transferase domain 35 171 1.6E-9 T 22-04-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 L21SP4_RS02325 6827269fb8fd9f9f6942991108efb49c 190 TIGRFAM TIGR01367 pyrE_Therm: orotate phosphoribosyltransferase 7 190 1.9E-53 T 22-04-2016 IPR006273 Orotate phosphoribosyltransferase, bacterial GO:0004588|GO:0019856 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|UniPathway: UPA00070 L21SP4_RS02325 6827269fb8fd9f9f6942991108efb49c 190 Gene3D G3DSA:3.40.50.2020 9 185 5.2E-38 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like L21SP4_RS09235 1812c31f4302ce126eb1532c32c7be2b 352 PANTHER PTHR30566 46 349 2.8E-57 T 22-04-2016 L21SP4_RS09235 1812c31f4302ce126eb1532c32c7be2b 352 PANTHER PTHR30566:SF5 46 349 2.8E-57 T 22-04-2016 L21SP4_RS09235 1812c31f4302ce126eb1532c32c7be2b 352 Gene3D G3DSA:2.30.30.60 190 239 3.6E-13 T 22-04-2016 L21SP4_RS09235 1812c31f4302ce126eb1532c32c7be2b 352 SUPERFAMILY SSF82689 242 343 3.4E-20 T 22-04-2016 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 L21SP4_RS09235 1812c31f4302ce126eb1532c32c7be2b 352 Pfam PF00924 Mechanosensitive ion channel 133 332 6.3E-46 T 22-04-2016 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 L21SP4_RS09235 1812c31f4302ce126eb1532c32c7be2b 352 SUPERFAMILY SSF50182 175 239 1.96E-12 T 22-04-2016 IPR010920 LSM domain L21SP4_RS09235 1812c31f4302ce126eb1532c32c7be2b 352 SUPERFAMILY SSF82861 93 173 8.5E-11 T 22-04-2016 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 L21SP4_RS09235 1812c31f4302ce126eb1532c32c7be2b 352 Gene3D G3DSA:3.30.70.100 243 330 1.7E-9 T 22-04-2016 L21SP4_RS00395 aad0d3464115a47db3914d0ab5982eda 141 Pfam PF02472 Biopolymer transport protein ExbD/TolR 9 136 1.5E-18 T 22-04-2016 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 L21SP4_RS00395 aad0d3464115a47db3914d0ab5982eda 141 PANTHER PTHR30558 1 140 1.5E-21 T 22-04-2016 L21SP4_RS00395 aad0d3464115a47db3914d0ab5982eda 141 PANTHER PTHR30558:SF3 1 140 1.5E-21 T 22-04-2016 L21SP4_RS04325 db20f7aeabc64ad5b31938c7f7f2d74c 516 PANTHER PTHR11922:SF2 7 513 6.2E-280 T 22-04-2016 L21SP4_RS04325 db20f7aeabc64ad5b31938c7f7f2d74c 516 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 9 195 1.8E-75 T 22-04-2016 IPR004739 GMP synthase, N-terminal GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|UniPathway: UPA00189 L21SP4_RS04325 db20f7aeabc64ad5b31938c7f7f2d74c 516 Gene3D G3DSA:3.40.50.880 9 195 6.8E-63 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like L21SP4_RS04325 db20f7aeabc64ad5b31938c7f7f2d74c 516 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 204 516 6.3E-146 T 22-04-2016 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|UniPathway: UPA00189 L21SP4_RS04325 db20f7aeabc64ad5b31938c7f7f2d74c 516 PRINTS PR00097 Anthranilate synthase component II signature 168 181 2.1E-6 T 22-04-2016 L21SP4_RS04325 db20f7aeabc64ad5b31938c7f7f2d74c 516 PRINTS PR00097 Anthranilate synthase component II signature 53 62 2.1E-6 T 22-04-2016 L21SP4_RS04325 db20f7aeabc64ad5b31938c7f7f2d74c 516 PRINTS PR00097 Anthranilate synthase component II signature 80 91 2.1E-6 T 22-04-2016 L21SP4_RS04325 db20f7aeabc64ad5b31938c7f7f2d74c 516 Pfam PF02540 NAD synthase 215 246 1.9E-5 T 22-04-2016 IPR022310 NAD/GMP synthase L21SP4_RS04325 db20f7aeabc64ad5b31938c7f7f2d74c 516 SUPERFAMILY SSF52317 8 228 2.65E-60 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like L21SP4_RS04325 db20f7aeabc64ad5b31938c7f7f2d74c 516 Gene3D G3DSA:3.30.300.10 392 516 4.6E-52 T 22-04-2016 L21SP4_RS04325 db20f7aeabc64ad5b31938c7f7f2d74c 516 SUPERFAMILY SSF54810 396 516 9.42E-51 T 22-04-2016 L21SP4_RS04325 db20f7aeabc64ad5b31938c7f7f2d74c 516 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 9 23 4.2E-5 T 22-04-2016 L21SP4_RS04325 db20f7aeabc64ad5b31938c7f7f2d74c 516 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 50 64 4.2E-5 T 22-04-2016 L21SP4_RS04325 db20f7aeabc64ad5b31938c7f7f2d74c 516 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 80 96 4.2E-5 T 22-04-2016 L21SP4_RS04325 db20f7aeabc64ad5b31938c7f7f2d74c 516 Gene3D G3DSA:3.40.50.620 199 389 1.0E-55 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP4_RS04325 db20f7aeabc64ad5b31938c7f7f2d74c 516 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 6 516 53.727 T 22-04-2016 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|UniPathway: UPA00189 L21SP4_RS04325 db20f7aeabc64ad5b31938c7f7f2d74c 516 PRINTS PR00096 Glutamine amidotransferase superfamily signature 53 62 4.9E-8 T 22-04-2016 L21SP4_RS04325 db20f7aeabc64ad5b31938c7f7f2d74c 516 PRINTS PR00096 Glutamine amidotransferase superfamily signature 80 91 4.9E-8 T 22-04-2016 L21SP4_RS04325 db20f7aeabc64ad5b31938c7f7f2d74c 516 PRINTS PR00096 Glutamine amidotransferase superfamily signature 168 181 4.9E-8 T 22-04-2016 L21SP4_RS04325 db20f7aeabc64ad5b31938c7f7f2d74c 516 Pfam PF00958 GMP synthase C terminal domain 424 515 7.2E-45 T 22-04-2016 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|UniPathway: UPA00189 L21SP4_RS04325 db20f7aeabc64ad5b31938c7f7f2d74c 516 Pfam PF00117 Glutamine amidotransferase class-I 11 190 2.5E-44 T 22-04-2016 IPR017926 Glutamine amidotransferase Reactome: REACT_1698 L21SP4_RS04325 db20f7aeabc64ad5b31938c7f7f2d74c 516 PANTHER PTHR11922 7 513 6.2E-280 T 22-04-2016 L21SP4_RS04325 db20f7aeabc64ad5b31938c7f7f2d74c 516 SUPERFAMILY SSF52402 188 410 3.31E-54 T 22-04-2016 L21SP4_RS10520 b1232f2c478fbf7162cac92ec7601abd 433 SUPERFAMILY SSF53335 144 428 6.84E-54 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS10520 b1232f2c478fbf7162cac92ec7601abd 433 Pfam PF01189 16S rRNA methyltransferase RsmB/F 238 427 5.2E-36 T 22-04-2016 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 L21SP4_RS10520 b1232f2c478fbf7162cac92ec7601abd 433 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 312 324 3.2E-16 T 22-04-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 L21SP4_RS10520 b1232f2c478fbf7162cac92ec7601abd 433 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 362 378 3.2E-16 T 22-04-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 L21SP4_RS10520 b1232f2c478fbf7162cac92ec7601abd 433 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 411 428 3.2E-16 T 22-04-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 L21SP4_RS10520 b1232f2c478fbf7162cac92ec7601abd 433 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 247 257 3.2E-16 T 22-04-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 L21SP4_RS10520 b1232f2c478fbf7162cac92ec7601abd 433 PANTHER PTHR22807 143 431 1.1E-55 T 22-04-2016 L21SP4_RS10520 b1232f2c478fbf7162cac92ec7601abd 433 Gene3D G3DSA:3.40.50.150 228 429 4.6E-43 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS02165 25ff783bbb643f61216e9246e8fb5fbd 400 PANTHER PTHR11587 1 400 2.4E-241 T 22-04-2016 L21SP4_RS02165 25ff783bbb643f61216e9246e8fb5fbd 400 Pfam PF00764 Arginosuccinate synthase 4 390 1.8E-161 T 22-04-2016 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 L21SP4_RS02165 25ff783bbb643f61216e9246e8fb5fbd 400 Gene3D G3DSA:1.20.5.470 362 389 2.1E-9 T 22-04-2016 L21SP4_RS02165 25ff783bbb643f61216e9246e8fb5fbd 400 TIGRFAM TIGR00032 argG: argininosuccinate synthase 2 390 3.6E-151 T 22-04-2016 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 L21SP4_RS02165 25ff783bbb643f61216e9246e8fb5fbd 400 Gene3D G3DSA:3.40.50.620 1 159 5.2E-64 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP4_RS02165 25ff783bbb643f61216e9246e8fb5fbd 400 Gene3D G3DSA:3.90.1260.10 160 353 7.7E-93 T 22-04-2016 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 L21SP4_RS02165 25ff783bbb643f61216e9246e8fb5fbd 400 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 6 14 - T 22-04-2016 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 L21SP4_RS02165 25ff783bbb643f61216e9246e8fb5fbd 400 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 114 125 - T 22-04-2016 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 L21SP4_RS02165 25ff783bbb643f61216e9246e8fb5fbd 400 PANTHER PTHR11587:SF2 1 400 2.4E-241 T 22-04-2016 L21SP4_RS02165 25ff783bbb643f61216e9246e8fb5fbd 400 SUPERFAMILY SSF69864 170 395 1.24E-91 T 22-04-2016 L21SP4_RS02165 25ff783bbb643f61216e9246e8fb5fbd 400 Hamap MF_00005 Argininosuccinate synthase [argG]. 1 396 51.422 T 22-04-2016 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 L21SP4_RS02165 25ff783bbb643f61216e9246e8fb5fbd 400 SUPERFAMILY SSF52402 1 202 4.19E-50 T 22-04-2016 L21SP4_RS05160 476ea4042ccd3b30a51bf160ef5709ea 224 PANTHER PTHR32125 3 223 9.5E-21 T 22-04-2016 L21SP4_RS05160 476ea4042ccd3b30a51bf160ef5709ea 224 Gene3D G3DSA:3.90.550.10 6 221 7.9E-39 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases L21SP4_RS05160 476ea4042ccd3b30a51bf160ef5709ea 224 PANTHER PTHR32125:SF4 3 223 9.5E-21 T 22-04-2016 L21SP4_RS05160 476ea4042ccd3b30a51bf160ef5709ea 224 SUPERFAMILY SSF53448 3 221 1.01E-28 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases L21SP4_RS05160 476ea4042ccd3b30a51bf160ef5709ea 224 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 6 220 7.4E-34 T 22-04-2016 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560|UniPathway: UPA00056 L21SP4_RS04240 eafbc7799c98c002fb6509e13de41435 718 SMART SM00387 449 565 7.5E-39 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS04240 eafbc7799c98c002fb6509e13de41435 718 Pfam PF00672 HAMP domain 251 318 2.2E-10 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 L21SP4_RS04240 eafbc7799c98c002fb6509e13de41435 718 SUPERFAMILY SSF158472 269 321 2.75E-6 T 22-04-2016 L21SP4_RS04240 eafbc7799c98c002fb6509e13de41435 718 Gene3D G3DSA:3.40.50.2300 591 708 8.6E-42 T 22-04-2016 L21SP4_RS04240 eafbc7799c98c002fb6509e13de41435 718 SMART SM00448 591 703 1.3E-36 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 L21SP4_RS04240 eafbc7799c98c002fb6509e13de41435 718 PANTHER PTHR24423 16 38 7.4E-156 T 22-04-2016 L21SP4_RS04240 eafbc7799c98c002fb6509e13de41435 718 PANTHER PTHR24423 277 718 7.4E-156 T 22-04-2016 L21SP4_RS04240 eafbc7799c98c002fb6509e13de41435 718 Gene3D G3DSA:1.10.287.130 329 398 8.0E-18 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS04240 eafbc7799c98c002fb6509e13de41435 718 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 449 564 3.5E-28 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS04240 eafbc7799c98c002fb6509e13de41435 718 SMART SM00388 337 402 2.6E-23 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS04240 eafbc7799c98c002fb6509e13de41435 718 PRINTS PR00344 Bacterial sensor protein C-terminal signature 549 562 2.5E-18 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS04240 eafbc7799c98c002fb6509e13de41435 718 PRINTS PR00344 Bacterial sensor protein C-terminal signature 490 504 2.5E-18 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS04240 eafbc7799c98c002fb6509e13de41435 718 PRINTS PR00344 Bacterial sensor protein C-terminal signature 525 543 2.5E-18 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS04240 eafbc7799c98c002fb6509e13de41435 718 PRINTS PR00344 Bacterial sensor protein C-terminal signature 508 518 2.5E-18 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS04240 eafbc7799c98c002fb6509e13de41435 718 SUPERFAMILY SSF52172 591 708 5.55E-38 T 22-04-2016 IPR011006 CheY-like superfamily L21SP4_RS04240 eafbc7799c98c002fb6509e13de41435 718 Gene3D G3DSA:3.30.565.10 402 566 2.6E-47 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS04240 eafbc7799c98c002fb6509e13de41435 718 SMART SM00304 268 322 5.9E-5 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 L21SP4_RS04240 eafbc7799c98c002fb6509e13de41435 718 SUPERFAMILY SSF55874 391 566 6.02E-46 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS04240 eafbc7799c98c002fb6509e13de41435 718 Pfam PF00512 His Kinase A (phospho-acceptor) domain 337 401 1.0E-18 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS04240 eafbc7799c98c002fb6509e13de41435 718 SUPERFAMILY SSF47384 322 403 1.96E-22 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS04240 eafbc7799c98c002fb6509e13de41435 718 PANTHER PTHR24423:SF491 16 38 7.4E-156 T 22-04-2016 L21SP4_RS04240 eafbc7799c98c002fb6509e13de41435 718 PANTHER PTHR24423:SF491 277 718 7.4E-156 T 22-04-2016 L21SP4_RS04240 eafbc7799c98c002fb6509e13de41435 718 Pfam PF00072 Response regulator receiver domain 593 701 2.6E-27 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 L21SP4_RS07255 6a2b7693f03343fe2a9dfcef85ff088a 843 SUPERFAMILY SSF53649 30 353 5.5E-82 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS07255 6a2b7693f03343fe2a9dfcef85ff088a 843 SUPERFAMILY SSF53649 391 436 5.5E-82 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS07255 6a2b7693f03343fe2a9dfcef85ff088a 843 Gene3D G3DSA:3.40.720.10 29 121 6.2E-27 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS07255 6a2b7693f03343fe2a9dfcef85ff088a 843 Pfam PF00884 Sulfatase 135 302 1.1E-21 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS07255 6a2b7693f03343fe2a9dfcef85ff088a 843 Pfam PF00884 Sulfatase 31 121 3.8E-17 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS07255 6a2b7693f03343fe2a9dfcef85ff088a 843 PANTHER PTHR10342 3 454 5.8E-85 T 22-04-2016 L21SP4_RS07255 6a2b7693f03343fe2a9dfcef85ff088a 843 PANTHER PTHR10342:SF199 3 454 5.8E-85 T 22-04-2016 L21SP4_RS07255 6a2b7693f03343fe2a9dfcef85ff088a 843 Gene3D G3DSA:3.40.720.10 148 341 6.8E-33 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS07255 6a2b7693f03343fe2a9dfcef85ff088a 843 ProSitePatterns PS00523 Sulfatases signature 1. 76 88 - T 22-04-2016 IPR024607 Sulfatase, conserved site L21SP4_RS07255 6a2b7693f03343fe2a9dfcef85ff088a 843 Gene3D G3DSA:3.30.1120.10 393 438 1.4E-13 T 22-04-2016 L21SP4_RS07255 6a2b7693f03343fe2a9dfcef85ff088a 843 Gene3D G3DSA:3.30.1120.10 342 355 1.4E-13 T 22-04-2016 L21SP4_RS09160 2e5d84d6bd979f1fcfe0eca42bea57a7 523 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 293 470 2.3E-17 T 22-04-2016 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 L21SP4_RS09160 2e5d84d6bd979f1fcfe0eca42bea57a7 523 Gene3D G3DSA:3.30.420.40 286 515 1.7E-19 T 22-04-2016 L21SP4_RS09160 2e5d84d6bd979f1fcfe0eca42bea57a7 523 PANTHER PTHR10196:SF57 3 522 7.4E-193 T 22-04-2016 L21SP4_RS09160 2e5d84d6bd979f1fcfe0eca42bea57a7 523 Gene3D G3DSA:3.30.420.40 2 283 1.1E-32 T 22-04-2016 L21SP4_RS09160 2e5d84d6bd979f1fcfe0eca42bea57a7 523 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 130 281 3.3E-18 T 22-04-2016 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 L21SP4_RS09160 2e5d84d6bd979f1fcfe0eca42bea57a7 523 SUPERFAMILY SSF53067 4 283 1.04E-35 T 22-04-2016 L21SP4_RS09160 2e5d84d6bd979f1fcfe0eca42bea57a7 523 SUPERFAMILY SSF53067 285 517 8.63E-30 T 22-04-2016 L21SP4_RS09160 2e5d84d6bd979f1fcfe0eca42bea57a7 523 PANTHER PTHR10196 3 522 7.4E-193 T 22-04-2016 L21SP4_RS08355 b52ba55b0eee5fc8a5311317e796f0bd 121 PANTHER PTHR11761:SF3 1 121 3.1E-63 T 22-04-2016 L21SP4_RS08355 b52ba55b0eee5fc8a5311317e796f0bd 121 SMART SM01374 1 121 5.4E-72 T 22-04-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 L21SP4_RS08355 b52ba55b0eee5fc8a5311317e796f0bd 121 SUPERFAMILY SSF50193 1 121 1.44E-45 T 22-04-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 L21SP4_RS08355 b52ba55b0eee5fc8a5311317e796f0bd 121 Pfam PF00238 Ribosomal protein L14p/L23e 1 121 7.9E-47 T 22-04-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 L21SP4_RS08355 b52ba55b0eee5fc8a5311317e796f0bd 121 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 121 1.3E-50 T 22-04-2016 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 L21SP4_RS08355 b52ba55b0eee5fc8a5311317e796f0bd 121 Gene3D G3DSA:2.40.150.20 1 121 1.0E-46 T 22-04-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 L21SP4_RS08355 b52ba55b0eee5fc8a5311317e796f0bd 121 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 121 24.324 T 22-04-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 L21SP4_RS08355 b52ba55b0eee5fc8a5311317e796f0bd 121 PANTHER PTHR11761 1 121 3.1E-63 T 22-04-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 L21SP4_RS09460 60ccd86a09380544b674371928a731c8 964 SMART SM00710 482 503 3300.0 T 22-04-2016 IPR006626 Parallel beta-helix repeat L21SP4_RS09460 60ccd86a09380544b674371928a731c8 964 SMART SM00710 883 913 330.0 T 22-04-2016 IPR006626 Parallel beta-helix repeat L21SP4_RS09460 60ccd86a09380544b674371928a731c8 964 SMART SM00710 723 748 3200.0 T 22-04-2016 IPR006626 Parallel beta-helix repeat L21SP4_RS09460 60ccd86a09380544b674371928a731c8 964 SMART SM00710 508 530 1500.0 T 22-04-2016 IPR006626 Parallel beta-helix repeat L21SP4_RS09460 60ccd86a09380544b674371928a731c8 964 SMART SM00710 408 430 1400.0 T 22-04-2016 IPR006626 Parallel beta-helix repeat L21SP4_RS09460 60ccd86a09380544b674371928a731c8 964 SMART SM00710 533 563 930.0 T 22-04-2016 IPR006626 Parallel beta-helix repeat L21SP4_RS09460 60ccd86a09380544b674371928a731c8 964 SMART SM00710 773 806 4800.0 T 22-04-2016 IPR006626 Parallel beta-helix repeat L21SP4_RS09460 60ccd86a09380544b674371928a731c8 964 Gene3D G3DSA:2.160.20.10 291 570 1.7E-24 T 22-04-2016 IPR012334 Pectin lyase fold L21SP4_RS09460 60ccd86a09380544b674371928a731c8 964 Gene3D G3DSA:2.160.20.10 851 944 9.7E-24 T 22-04-2016 IPR012334 Pectin lyase fold L21SP4_RS09460 60ccd86a09380544b674371928a731c8 964 Gene3D G3DSA:2.160.20.10 640 809 9.7E-24 T 22-04-2016 IPR012334 Pectin lyase fold L21SP4_RS09460 60ccd86a09380544b674371928a731c8 964 Pfam PF12708 Pectate lyase superfamily protein 294 512 6.2E-16 T 22-04-2016 IPR024535 Pectate lyase superfamily protein L21SP4_RS09460 60ccd86a09380544b674371928a731c8 964 Pfam PF12708 Pectate lyase superfamily protein 640 792 5.5E-13 T 22-04-2016 IPR024535 Pectate lyase superfamily protein L21SP4_RS09460 60ccd86a09380544b674371928a731c8 964 SUPERFAMILY SSF51126 284 597 2.99E-29 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor L21SP4_RS09460 60ccd86a09380544b674371928a731c8 964 SUPERFAMILY SSF51126 841 942 2.6E-27 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor L21SP4_RS09460 60ccd86a09380544b674371928a731c8 964 SUPERFAMILY SSF51126 633 787 2.6E-27 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor L21SP4_RS09405 fb0144813fd953f85ff0edfa3216a171 469 Pfam PF00884 Sulfatase 18 364 2.2E-67 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS09405 fb0144813fd953f85ff0edfa3216a171 469 SUPERFAMILY SSF53649 16 460 1.6E-115 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS09405 fb0144813fd953f85ff0edfa3216a171 469 Gene3D G3DSA:3.30.1120.10 390 460 3.2E-18 T 22-04-2016 L21SP4_RS09405 fb0144813fd953f85ff0edfa3216a171 469 Gene3D G3DSA:3.40.720.10 15 383 6.4E-102 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS09405 fb0144813fd953f85ff0edfa3216a171 469 PANTHER PTHR10342 1 456 5.5E-123 T 22-04-2016 L21SP4_RS11875 8040b172224102d5733dc56c51b17a64 626 Pfam PF07470 Glycosyl Hydrolase Family 88 45 363 3.4E-82 T 22-04-2016 IPR010905 Glycosyl hydrolase, family 88 L21SP4_RS11875 8040b172224102d5733dc56c51b17a64 626 Pfam PF16153 Domain of unknown function (DUF4861) 377 622 4.2E-57 T 22-04-2016 IPR032342 Protein of unknown function DUF4861 L21SP4_RS11875 8040b172224102d5733dc56c51b17a64 626 PANTHER PTHR33886:SF2 16 366 9.7E-93 T 22-04-2016 L21SP4_RS11875 8040b172224102d5733dc56c51b17a64 626 SUPERFAMILY SSF48208 54 365 2.72E-43 T 22-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP4_RS11875 8040b172224102d5733dc56c51b17a64 626 Gene3D G3DSA:1.50.10.10 31 365 6.7E-84 T 22-04-2016 IPR012341 Six-hairpin glycosidase GO:0003824 L21SP4_RS11875 8040b172224102d5733dc56c51b17a64 626 PANTHER PTHR33886 16 366 9.7E-93 T 22-04-2016 L21SP4_RS11155 293dcc609fdb25353181eec7d64ca54a 85 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 8 84 6.2E-11 T 22-04-2016 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family L21SP4_RS11155 293dcc609fdb25353181eec7d64ca54a 85 PANTHER PTHR38813:SF1 3 84 4.4E-17 T 22-04-2016 L21SP4_RS11155 293dcc609fdb25353181eec7d64ca54a 85 PANTHER PTHR38813 3 84 4.4E-17 T 22-04-2016 L21SP4_RS11155 293dcc609fdb25353181eec7d64ca54a 85 SUPERFAMILY SSF143011 4 83 4.05E-21 T 22-04-2016 L21SP4_RS07600 8032c21d179c59e0714c5b52e977d121 121 TIGRFAM TIGR02436 TIGR02436: four helix bundle protein 10 116 1.3E-23 T 22-04-2016 IPR012657 23S rRNA-intervening sequence protein L21SP4_RS07600 8032c21d179c59e0714c5b52e977d121 121 SUPERFAMILY SSF158446 3 116 3.4E-25 T 22-04-2016 L21SP4_RS07600 8032c21d179c59e0714c5b52e977d121 121 Gene3D G3DSA:1.20.1440.60 3 116 3.7E-22 T 22-04-2016 IPR012657 23S rRNA-intervening sequence protein L21SP4_RS07600 8032c21d179c59e0714c5b52e977d121 121 Pfam PF05635 23S rRNA-intervening sequence protein 6 111 2.5E-23 T 22-04-2016 IPR012657 23S rRNA-intervening sequence protein L21SP4_RS04435 39801e4147c877e27b10b2650a542c94 688 Gene3D G3DSA:3.30.1120.10 430 495 2.6E-17 T 22-04-2016 L21SP4_RS04435 39801e4147c877e27b10b2650a542c94 688 SUPERFAMILY SSF53649 29 493 4.22E-131 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS04435 39801e4147c877e27b10b2650a542c94 688 PANTHER PTHR10342 262 316 2.4E-131 T 22-04-2016 L21SP4_RS04435 39801e4147c877e27b10b2650a542c94 688 PANTHER PTHR10342 7 232 2.4E-131 T 22-04-2016 L21SP4_RS04435 39801e4147c877e27b10b2650a542c94 688 PANTHER PTHR10342 342 516 2.4E-131 T 22-04-2016 L21SP4_RS04435 39801e4147c877e27b10b2650a542c94 688 Pfam PF00884 Sulfatase 30 398 2.4E-68 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS04435 39801e4147c877e27b10b2650a542c94 688 PANTHER PTHR10342:SF199 262 316 2.4E-131 T 22-04-2016 L21SP4_RS04435 39801e4147c877e27b10b2650a542c94 688 PANTHER PTHR10342:SF199 7 232 2.4E-131 T 22-04-2016 L21SP4_RS04435 39801e4147c877e27b10b2650a542c94 688 PANTHER PTHR10342:SF199 342 516 2.4E-131 T 22-04-2016 L21SP4_RS04435 39801e4147c877e27b10b2650a542c94 688 Gene3D G3DSA:3.40.720.10 27 423 3.1E-110 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS05105 ab1528b765378f0a67a153a5689100bb 184 Gene3D G3DSA:3.40.30.10 60 180 7.9E-37 T 22-04-2016 IPR012336 Thioredoxin-like fold L21SP4_RS05105 ab1528b765378f0a67a153a5689100bb 184 SUPERFAMILY SSF52833 54 160 8.04E-25 T 22-04-2016 IPR012336 Thioredoxin-like fold L21SP4_RS05105 ab1528b765378f0a67a153a5689100bb 184 PANTHER PTHR13871 42 184 8.3E-58 T 22-04-2016 L21SP4_RS05105 ab1528b765378f0a67a153a5689100bb 184 Pfam PF13905 Thioredoxin-like 64 157 1.9E-28 T 22-04-2016 IPR012336 Thioredoxin-like fold L21SP4_RS08390 6f05426e8733c29e9704852c7a055a51 274 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 274 45.64 T 22-04-2016 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 L21SP4_RS08390 6f05426e8733c29e9704852c7a055a51 274 ProSitePatterns PS00467 Ribosomal protein L2 signature. 218 229 - T 22-04-2016 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 L21SP4_RS08390 6f05426e8733c29e9704852c7a055a51 274 Gene3D G3DSA:2.30.30.30 120 195 6.6E-28 T 22-04-2016 IPR014722 Ribosomal protein L2 domain 2 L21SP4_RS08390 6f05426e8733c29e9704852c7a055a51 274 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 273 2.4E-122 T 22-04-2016 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 L21SP4_RS08390 6f05426e8733c29e9704852c7a055a51 274 PANTHER PTHR13691:SF5 1 274 4.9E-125 T 22-04-2016 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 L21SP4_RS08390 6f05426e8733c29e9704852c7a055a51 274 SUPERFAMILY SSF50104 127 272 1.62E-55 T 22-04-2016 IPR008991 Translation protein SH3-like domain L21SP4_RS08390 6f05426e8733c29e9704852c7a055a51 274 SMART SM01382 124 252 1.2E-77 T 22-04-2016 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 L21SP4_RS08390 6f05426e8733c29e9704852c7a055a51 274 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 118 3.7E-30 T 22-04-2016 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS08390 6f05426e8733c29e9704852c7a055a51 274 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 126 250 1.6E-51 T 22-04-2016 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 L21SP4_RS08390 6f05426e8733c29e9704852c7a055a51 274 Gene3D G3DSA:4.10.950.10 199 273 6.7E-32 T 22-04-2016 IPR014726 Ribosomal protein L2, domain 3 L21SP4_RS08390 6f05426e8733c29e9704852c7a055a51 274 PIRSF PIRSF002158 3 274 2.3E-96 T 22-04-2016 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS08390 6f05426e8733c29e9704852c7a055a51 274 SMART SM01383 42 118 6.2E-43 T 22-04-2016 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS08390 6f05426e8733c29e9704852c7a055a51 274 SUPERFAMILY SSF50249 3 122 5.14E-47 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold L21SP4_RS08390 6f05426e8733c29e9704852c7a055a51 274 PANTHER PTHR13691 1 274 4.9E-125 T 22-04-2016 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS08390 6f05426e8733c29e9704852c7a055a51 274 Gene3D G3DSA:2.40.50.140 1 113 1.1E-49 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold L21SP4_RS00035 b3e6b682ed2b525aa7e64802b2134308 435 Pfam PF02082 Transcriptional regulator 313 392 1.1E-5 T 22-04-2016 IPR000944 Transcription regulator Rrf2-type L21SP4_RS00035 b3e6b682ed2b525aa7e64802b2134308 435 PANTHER PTHR30213:SF0 13 435 3.3E-75 T 22-04-2016 L21SP4_RS00035 b3e6b682ed2b525aa7e64802b2134308 435 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 46 293 6.6E-40 T 22-04-2016 IPR017039 Virulence factor BrkB L21SP4_RS00035 b3e6b682ed2b525aa7e64802b2134308 435 Pfam PF03631 Virulence factor BrkB 51 296 5.1E-52 T 22-04-2016 IPR017039 Virulence factor BrkB L21SP4_RS00035 b3e6b682ed2b525aa7e64802b2134308 435 PANTHER PTHR30213 13 435 3.3E-75 T 22-04-2016 L21SP4_RS00035 b3e6b682ed2b525aa7e64802b2134308 435 SUPERFAMILY SSF46785 316 435 2.42E-5 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS00035 b3e6b682ed2b525aa7e64802b2134308 435 Gene3D G3DSA:1.10.10.10 314 435 2.8E-8 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS06025 437c73534eacc0072e19b8a38200bcd2 500 SUPERFAMILY SSF53649 27 481 8.43E-127 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS06025 437c73534eacc0072e19b8a38200bcd2 500 Gene3D G3DSA:3.30.1120.10 403 481 1.6E-17 T 22-04-2016 L21SP4_RS06025 437c73534eacc0072e19b8a38200bcd2 500 Pfam PF16347 Domain of unknown function (DUF4976) 377 480 6.3E-26 T 22-04-2016 IPR032506 Domain of unknown function DUF4976 L21SP4_RS06025 437c73534eacc0072e19b8a38200bcd2 500 PANTHER PTHR10342 1 224 7.1E-155 T 22-04-2016 L21SP4_RS06025 437c73534eacc0072e19b8a38200bcd2 500 PANTHER PTHR10342 265 500 7.1E-155 T 22-04-2016 L21SP4_RS06025 437c73534eacc0072e19b8a38200bcd2 500 PANTHER PTHR10342:SF237 1 224 7.1E-155 T 22-04-2016 L21SP4_RS06025 437c73534eacc0072e19b8a38200bcd2 500 PANTHER PTHR10342:SF237 265 500 7.1E-155 T 22-04-2016 L21SP4_RS06025 437c73534eacc0072e19b8a38200bcd2 500 ProSitePatterns PS00523 Sulfatases signature 1. 74 86 - T 22-04-2016 IPR024607 Sulfatase, conserved site L21SP4_RS06025 437c73534eacc0072e19b8a38200bcd2 500 Gene3D G3DSA:3.40.720.10 27 390 7.9E-109 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS06025 437c73534eacc0072e19b8a38200bcd2 500 ProSitePatterns PS00149 Sulfatases signature 2. 116 126 - T 22-04-2016 IPR024607 Sulfatase, conserved site L21SP4_RS06025 437c73534eacc0072e19b8a38200bcd2 500 Pfam PF00884 Sulfatase 28 373 8.1E-70 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS09550 f366d8b848a600df7494d78dd5c1d2ff 459 PANTHER PTHR37560 1 459 2.5E-169 T 22-04-2016 L21SP4_RS09550 f366d8b848a600df7494d78dd5c1d2ff 459 PANTHER PTHR37560:SF1 1 459 2.5E-169 T 22-04-2016 L21SP4_RS09550 f366d8b848a600df7494d78dd5c1d2ff 459 SUPERFAMILY SSF51998 4 454 1.83E-143 T 22-04-2016 L21SP4_RS09550 f366d8b848a600df7494d78dd5c1d2ff 459 Pfam PF05167 Uncharacterised ACR (DUF711) 13 422 1.7E-152 T 22-04-2016 IPR007841 Uncharacterised protein family UPF0210 L21SP4_RS09550 f366d8b848a600df7494d78dd5c1d2ff 459 Gene3D G3DSA:3.20.70.20 1 459 2.7E-171 T 22-04-2016 L21SP4_RS11815 5c6c8a2ce4bfdd0efe8e98e6b4a3e6c8 623 Pfam PF00884 Sulfatase 2 316 1.8E-51 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS11815 5c6c8a2ce4bfdd0efe8e98e6b4a3e6c8 623 ProSitePatterns PS00523 Sulfatases signature 1. 11 23 - T 22-04-2016 IPR024607 Sulfatase, conserved site L21SP4_RS11815 5c6c8a2ce4bfdd0efe8e98e6b4a3e6c8 623 PANTHER PTHR10342 1 241 5.8E-115 T 22-04-2016 L21SP4_RS11815 5c6c8a2ce4bfdd0efe8e98e6b4a3e6c8 623 PANTHER PTHR10342 261 442 5.8E-115 T 22-04-2016 L21SP4_RS11815 5c6c8a2ce4bfdd0efe8e98e6b4a3e6c8 623 SUPERFAMILY SSF53649 1 423 3.78E-99 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS11815 5c6c8a2ce4bfdd0efe8e98e6b4a3e6c8 623 PANTHER PTHR10342:SF199 1 241 5.8E-115 T 22-04-2016 L21SP4_RS11815 5c6c8a2ce4bfdd0efe8e98e6b4a3e6c8 623 PANTHER PTHR10342:SF199 261 442 5.8E-115 T 22-04-2016 L21SP4_RS11815 5c6c8a2ce4bfdd0efe8e98e6b4a3e6c8 623 Gene3D G3DSA:3.40.720.10 1 336 3.5E-80 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS11815 5c6c8a2ce4bfdd0efe8e98e6b4a3e6c8 623 Gene3D G3DSA:3.30.1120.10 358 430 1.7E-18 T 22-04-2016 L21SP4_RS11120 20e72365026b416a01917100477831f0 400 SUPERFAMILY SSF52540 10 125 1.54E-13 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS11120 20e72365026b416a01917100477831f0 400 PANTHER PTHR33295 1 395 4.3E-88 T 22-04-2016 L21SP4_RS11120 20e72365026b416a01917100477831f0 400 Pfam PF13635 Domain of unknown function (DUF4143) 148 348 1.7E-22 T 22-04-2016 IPR025420 Domain of unknown function DUF4143 L21SP4_RS11120 20e72365026b416a01917100477831f0 400 Gene3D G3DSA:3.40.1350.10 293 349 1.6E-4 T 22-04-2016 IPR011856 tRNA endonuclease-like domain GO:0003676|GO:0004518 L21SP4_RS11120 20e72365026b416a01917100477831f0 400 Pfam PF13173 AAA domain 9 124 7.7E-23 T 22-04-2016 L21SP4_RS11120 20e72365026b416a01917100477831f0 400 PANTHER PTHR33295:SF5 1 395 4.3E-88 T 22-04-2016 L21SP4_RS01175 2c18f71d23c2b6e366de532bb19117b4 247 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 186 4.9E-5 T 22-04-2016 L21SP4_RS01175 2c18f71d23c2b6e366de532bb19117b4 247 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 245 1.1E-73 T 22-04-2016 L21SP4_RS01175 2c18f71d23c2b6e366de532bb19117b4 247 Gene3D G3DSA:3.40.50.720 2 247 1.8E-96 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS01175 2c18f71d23c2b6e366de532bb19117b4 247 PANTHER PTHR24322 155 186 1.7E-62 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS01175 2c18f71d23c2b6e366de532bb19117b4 247 PANTHER PTHR24322 11 139 1.7E-62 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS01175 2c18f71d23c2b6e366de532bb19117b4 247 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 9 246 2.5E-103 T 22-04-2016 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321|UniPathway: UPA00094 L21SP4_RS01175 2c18f71d23c2b6e366de532bb19117b4 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 9.4E-48 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS01175 2c18f71d23c2b6e366de532bb19117b4 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 9.4E-48 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS01175 2c18f71d23c2b6e366de532bb19117b4 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 9.4E-48 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS01175 2c18f71d23c2b6e366de532bb19117b4 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 9.4E-48 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS01175 2c18f71d23c2b6e366de532bb19117b4 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 9.4E-48 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS01175 2c18f71d23c2b6e366de532bb19117b4 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 9.4E-48 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS01175 2c18f71d23c2b6e366de532bb19117b4 247 SUPERFAMILY SSF51735 5 247 4.27E-92 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS01175 2c18f71d23c2b6e366de532bb19117b4 247 PANTHER PTHR24322:SF328 155 186 1.7E-62 T 22-04-2016 L21SP4_RS01175 2c18f71d23c2b6e366de532bb19117b4 247 PANTHER PTHR24322:SF328 11 139 1.7E-62 T 22-04-2016 L21SP4_RS01175 2c18f71d23c2b6e366de532bb19117b4 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 1.5E-15 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS01175 2c18f71d23c2b6e366de532bb19117b4 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 1.5E-15 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS01175 2c18f71d23c2b6e366de532bb19117b4 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 1.5E-15 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS01175 2c18f71d23c2b6e366de532bb19117b4 247 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 22-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 L21SP4_RS05180 d437edadde9dbbfebb10ffbd15e0c8a3 273 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 225 247 - T 22-04-2016 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|UniPathway: UPA00098 L21SP4_RS05180 d437edadde9dbbfebb10ffbd15e0c8a3 273 PANTHER PTHR11645 3 269 1.5E-105 T 22-04-2016 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|UniPathway: UPA00098 L21SP4_RS05180 d437edadde9dbbfebb10ffbd15e0c8a3 273 PANTHER PTHR11645:SF0 3 269 1.5E-105 T 22-04-2016 L21SP4_RS05180 d437edadde9dbbfebb10ffbd15e0c8a3 273 PIRSF PIRSF000193 5 272 2.7E-77 T 22-04-2016 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|UniPathway: UPA00098 L21SP4_RS05180 d437edadde9dbbfebb10ffbd15e0c8a3 273 Gene3D G3DSA:1.10.3730.10 165 269 6.5E-38 T 22-04-2016 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|UniPathway: UPA00098 L21SP4_RS05180 d437edadde9dbbfebb10ffbd15e0c8a3 273 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 8 102 5.0E-20 T 22-04-2016 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal L21SP4_RS05180 d437edadde9dbbfebb10ffbd15e0c8a3 273 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 8 269 1.6E-82 T 22-04-2016 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|UniPathway: UPA00098 L21SP4_RS05180 d437edadde9dbbfebb10ffbd15e0c8a3 273 SUPERFAMILY SSF48179 165 270 2.04E-33 T 22-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 L21SP4_RS05180 d437edadde9dbbfebb10ffbd15e0c8a3 273 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 165 269 7.9E-37 T 22-04-2016 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|UniPathway: UPA00098 L21SP4_RS05180 d437edadde9dbbfebb10ffbd15e0c8a3 273 Gene3D G3DSA:3.40.50.720 4 161 4.1E-47 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS05180 d437edadde9dbbfebb10ffbd15e0c8a3 273 SUPERFAMILY SSF51735 7 161 6.12E-35 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS05180 d437edadde9dbbfebb10ffbd15e0c8a3 273 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 6 269 26.962 T 22-04-2016 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|UniPathway: UPA00098 L21SP4_RS00165 1f70c48b72e139fcadf6df00659c8b41 277 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 53 272 1.6E-52 T 22-04-2016 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 L21SP4_RS00165 1f70c48b72e139fcadf6df00659c8b41 277 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 180 186 - T 22-04-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 L21SP4_RS00165 1f70c48b72e139fcadf6df00659c8b41 277 Pfam PF05175 Methyltransferase small domain 109 190 1.6E-15 T 22-04-2016 IPR007848 Methyltransferase small domain GO:0008168 L21SP4_RS00165 1f70c48b72e139fcadf6df00659c8b41 277 PANTHER PTHR18895:SF64 48 274 1.0E-71 T 22-04-2016 L21SP4_RS00165 1f70c48b72e139fcadf6df00659c8b41 277 PANTHER PTHR18895 48 274 1.0E-71 T 22-04-2016 L21SP4_RS00165 1f70c48b72e139fcadf6df00659c8b41 277 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 50 272 1.9E-68 T 22-04-2016 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 L21SP4_RS00165 1f70c48b72e139fcadf6df00659c8b41 277 SUPERFAMILY SSF53335 51 272 1.07E-46 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS00165 1f70c48b72e139fcadf6df00659c8b41 277 Gene3D G3DSA:3.40.50.150 82 276 5.2E-62 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS06260 fad5d25a6ac38061dbad494ea3de64c9 574 Hamap MF_00309 V-type ATP synthase alpha chain [atpA]. 3 573 43.91 T 22-04-2016 IPR022878 V-type ATP synthase catalytic alpha chain GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 L21SP4_RS06260 fad5d25a6ac38061dbad494ea3de64c9 574 PANTHER PTHR15184:SF7 3 103 1.5E-189 T 22-04-2016 L21SP4_RS06260 fad5d25a6ac38061dbad494ea3de64c9 574 PANTHER PTHR15184:SF7 188 573 1.5E-189 T 22-04-2016 L21SP4_RS06260 fad5d25a6ac38061dbad494ea3de64c9 574 SUPERFAMILY SSF50615 3 74 3.61E-5 T 22-04-2016 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 L21SP4_RS06260 fad5d25a6ac38061dbad494ea3de64c9 574 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 220 440 1.8E-74 T 22-04-2016 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 L21SP4_RS06260 fad5d25a6ac38061dbad494ea3de64c9 574 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 9 72 2.6E-8 T 22-04-2016 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 L21SP4_RS06260 fad5d25a6ac38061dbad494ea3de64c9 574 Pfam PF16886 ATPsynthase alpha/beta subunit N-term extension 88 208 2.9E-37 T 22-04-2016 IPR031686 ATPsynthase alpha/beta subunit, N-terminal extension KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 L21SP4_RS06260 fad5d25a6ac38061dbad494ea3de64c9 574 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 431 440 - T 22-04-2016 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 L21SP4_RS06260 fad5d25a6ac38061dbad494ea3de64c9 574 SUPERFAMILY SSF52540 169 445 2.24E-74 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS06260 fad5d25a6ac38061dbad494ea3de64c9 574 PANTHER PTHR15184 3 103 1.5E-189 T 22-04-2016 L21SP4_RS06260 fad5d25a6ac38061dbad494ea3de64c9 574 PANTHER PTHR15184 188 573 1.5E-189 T 22-04-2016 L21SP4_RS06260 fad5d25a6ac38061dbad494ea3de64c9 574 Gene3D G3DSA:3.40.50.300 170 440 5.6E-84 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS02425 79e6590652e3b9d8d1871061b555637e 506 PANTHER PTHR12526:SF17 35 501 4.7E-64 T 22-04-2016 L21SP4_RS02425 79e6590652e3b9d8d1871061b555637e 506 PANTHER PTHR12526 35 501 4.7E-64 T 22-04-2016 L21SP4_RS02425 79e6590652e3b9d8d1871061b555637e 506 Gene3D G3DSA:3.40.50.2000 267 475 5.2E-47 T 22-04-2016 L21SP4_RS02425 79e6590652e3b9d8d1871061b555637e 506 Pfam PF08323 Starch synthase catalytic domain 11 236 8.8E-38 T 22-04-2016 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622|UniPathway: UPA00164 L21SP4_RS02425 79e6590652e3b9d8d1871061b555637e 506 SUPERFAMILY SSF53756 33 499 8.48E-63 T 22-04-2016 L21SP4_RS05435 ee4fb7f92abb0592f8e79da90e644666 263 SMART SM00382 31 220 2.8E-10 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS05435 ee4fb7f92abb0592f8e79da90e644666 263 Gene3D G3DSA:3.40.50.300 8 233 9.5E-55 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS05435 ee4fb7f92abb0592f8e79da90e644666 263 PANTHER PTHR24220:SF266 8 250 6.8E-77 T 22-04-2016 L21SP4_RS05435 ee4fb7f92abb0592f8e79da90e644666 263 SUPERFAMILY SSF52540 5 234 8.64E-56 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS05435 ee4fb7f92abb0592f8e79da90e644666 263 Pfam PF00005 ABC transporter 22 170 1.6E-28 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 L21SP4_RS05435 ee4fb7f92abb0592f8e79da90e644666 263 PANTHER PTHR24220 8 250 6.8E-77 T 22-04-2016 L21SP4_RS01025 addab9bfe8b75c051967f135de33d33c 218 PANTHER PTHR10204 1 211 5.2E-32 T 22-04-2016 L21SP4_RS01025 addab9bfe8b75c051967f135de33d33c 218 SUPERFAMILY SSF52218 2 211 4.89E-38 T 22-04-2016 IPR029039 Flavoprotein-like domain L21SP4_RS01025 addab9bfe8b75c051967f135de33d33c 218 PANTHER PTHR10204:SF4 1 211 5.2E-32 T 22-04-2016 L21SP4_RS01025 addab9bfe8b75c051967f135de33d33c 218 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 1 214 22.029 T 22-04-2016 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 L21SP4_RS01025 addab9bfe8b75c051967f135de33d33c 218 Pfam PF02525 Flavodoxin-like fold 2 199 2.4E-34 T 22-04-2016 IPR003680 Flavodoxin-like fold L21SP4_RS01025 addab9bfe8b75c051967f135de33d33c 218 Gene3D G3DSA:3.40.50.360 2 209 2.3E-43 T 22-04-2016 IPR029039 Flavoprotein-like domain L21SP4_RS05800 7cfa684b8992b181aca97d21668213a0 225 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 103 187 1.8E-23 T 22-04-2016 IPR020057 Ribosomal protein L25, beta domain L21SP4_RS05800 7cfa684b8992b181aca97d21668213a0 225 Gene3D G3DSA:2.40.240.10 6 98 2.3E-21 T 22-04-2016 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: REACT_71 L21SP4_RS05800 7cfa684b8992b181aca97d21668213a0 225 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 5 98 8.0E-9 T 22-04-2016 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 L21SP4_RS05800 7cfa684b8992b181aca97d21668213a0 225 Gene3D G3DSA:2.170.120.20 101 192 3.4E-26 T 22-04-2016 IPR020057 Ribosomal protein L25, beta domain L21SP4_RS05800 7cfa684b8992b181aca97d21668213a0 225 SUPERFAMILY SSF50715 5 192 6.98E-46 T 22-04-2016 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: REACT_71 L21SP4_RS05800 7cfa684b8992b181aca97d21668213a0 225 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 5 187 23.908 T 22-04-2016 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 L21SP4_RS05800 7cfa684b8992b181aca97d21668213a0 225 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 7 184 4.4E-42 T 22-04-2016 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 L21SP4_RS05800 7cfa684b8992b181aca97d21668213a0 225 PANTHER PTHR33284 7 211 5.0E-46 T 22-04-2016 L21SP4_RS05800 7cfa684b8992b181aca97d21668213a0 225 Pfam PF01386 Ribosomal L25p family 7 95 1.5E-17 T 22-04-2016 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 L21SP4_RS04125 c07df48ad1d9651517cde048387d0d00 432 PANTHER PTHR11739 23 423 1.6E-170 T 22-04-2016 IPR002020 Citrate synthase GO:0046912 L21SP4_RS04125 c07df48ad1d9651517cde048387d0d00 432 Gene3D G3DSA:1.10.230.10 285 378 3.5E-36 T 22-04-2016 IPR016143 Citrate synthase-like, small alpha subdomain L21SP4_RS04125 c07df48ad1d9651517cde048387d0d00 432 PRINTS PR00143 Citrate synthase signature 168 181 6.8E-49 T 22-04-2016 IPR002020 Citrate synthase GO:0046912 L21SP4_RS04125 c07df48ad1d9651517cde048387d0d00 432 PRINTS PR00143 Citrate synthase signature 301 321 6.8E-49 T 22-04-2016 IPR002020 Citrate synthase GO:0046912 L21SP4_RS04125 c07df48ad1d9651517cde048387d0d00 432 PRINTS PR00143 Citrate synthase signature 222 237 6.8E-49 T 22-04-2016 IPR002020 Citrate synthase GO:0046912 L21SP4_RS04125 c07df48ad1d9651517cde048387d0d00 432 PRINTS PR00143 Citrate synthase signature 244 272 6.8E-49 T 22-04-2016 IPR002020 Citrate synthase GO:0046912 L21SP4_RS04125 c07df48ad1d9651517cde048387d0d00 432 PRINTS PR00143 Citrate synthase signature 384 398 6.8E-49 T 22-04-2016 IPR002020 Citrate synthase GO:0046912 L21SP4_RS04125 c07df48ad1d9651517cde048387d0d00 432 PRINTS PR00143 Citrate synthase signature 364 380 6.8E-49 T 22-04-2016 IPR002020 Citrate synthase GO:0046912 L21SP4_RS04125 c07df48ad1d9651517cde048387d0d00 432 SUPERFAMILY SSF48256 12 429 4.19E-148 T 22-04-2016 IPR002020 Citrate synthase GO:0046912 L21SP4_RS04125 c07df48ad1d9651517cde048387d0d00 432 PIRSF PIRSF001369 41 432 3.9E-146 T 22-04-2016 IPR024176 Citrate synthase, bacterial-type UniPathway: UPA00223 L21SP4_RS04125 c07df48ad1d9651517cde048387d0d00 432 TIGRFAM TIGR01798 cit_synth_I: citrate (Si)-synthase 17 424 7.9E-166 T 22-04-2016 IPR010953 Citrate synthase, type I GO:0004108|GO:0005737 UniPathway: UPA00223 L21SP4_RS04125 c07df48ad1d9651517cde048387d0d00 432 ProSitePatterns PS00480 Citrate synthase signature. 308 320 - T 22-04-2016 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 UniPathway: UPA00223 L21SP4_RS04125 c07df48ad1d9651517cde048387d0d00 432 Gene3D G3DSA:1.10.580.10 56 284 7.0E-85 T 22-04-2016 IPR016142 Citrate synthase-like, large alpha subdomain UniPathway: UPA00223 L21SP4_RS04125 c07df48ad1d9651517cde048387d0d00 432 Pfam PF00285 Citrate synthase, C-terminal domain 50 416 6.6E-126 T 22-04-2016 IPR002020 Citrate synthase GO:0046912 L21SP4_RS03890 60b8ea751bdfeccee1b4090170b01917 109 PRINTS PR01853 Bacterial YajC preprotein translocase signature 16 36 2.2E-11 T 22-04-2016 IPR003849 Preprotein translocase YajC L21SP4_RS03890 60b8ea751bdfeccee1b4090170b01917 109 PRINTS PR01853 Bacterial YajC preprotein translocase signature 36 54 2.2E-11 T 22-04-2016 IPR003849 Preprotein translocase YajC L21SP4_RS03890 60b8ea751bdfeccee1b4090170b01917 109 PANTHER PTHR33909 1 100 2.5E-24 T 22-04-2016 L21SP4_RS03890 60b8ea751bdfeccee1b4090170b01917 109 SMART SM01323 14 96 1.5E-37 T 22-04-2016 IPR003849 Preprotein translocase YajC L21SP4_RS03890 60b8ea751bdfeccee1b4090170b01917 109 Pfam PF02699 Preprotein translocase subunit 18 94 2.4E-26 T 22-04-2016 IPR003849 Preprotein translocase YajC L21SP4_RS03890 60b8ea751bdfeccee1b4090170b01917 109 PANTHER PTHR33909:SF1 1 100 2.5E-24 T 22-04-2016 L21SP4_RS03890 60b8ea751bdfeccee1b4090170b01917 109 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 21 96 7.2E-26 T 22-04-2016 IPR003849 Preprotein translocase YajC L21SP4_RS00325 578272ff9199bda3c9a59352349145ce 253 PANTHER PTHR13767 1 249 9.9E-99 T 22-04-2016 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 L21SP4_RS00325 578272ff9199bda3c9a59352349145ce 253 SUPERFAMILY SSF55120 18 240 1.13E-76 T 22-04-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 L21SP4_RS00325 578272ff9199bda3c9a59352349145ce 253 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 18 224 9.5E-68 T 22-04-2016 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 L21SP4_RS00325 578272ff9199bda3c9a59352349145ce 253 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 39 187 5.1E-54 T 22-04-2016 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 L21SP4_RS00325 578272ff9199bda3c9a59352349145ce 253 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 17 250 16.304 T 22-04-2016 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 L21SP4_RS00325 578272ff9199bda3c9a59352349145ce 253 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 188 244 3.0E-13 T 22-04-2016 IPR032819 tRNA pseudouridylate synthase B, C-terminal L21SP4_RS04650 9a49206ccc0668c3f777640bbe38fd96 424 Gene3D G3DSA:3.10.580.10 190 318 3.2E-21 T 22-04-2016 L21SP4_RS04650 9a49206ccc0668c3f777640bbe38fd96 424 SUPERFAMILY SSF56176 338 419 3.54E-19 T 22-04-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 L21SP4_RS04650 9a49206ccc0668c3f777640bbe38fd96 424 Pfam PF00571 CBS domain 205 262 4.8E-4 T 22-04-2016 IPR000644 CBS domain L21SP4_RS04650 9a49206ccc0668c3f777640bbe38fd96 424 Pfam PF00571 CBS domain 276 323 1.8E-5 T 22-04-2016 IPR000644 CBS domain L21SP4_RS04650 9a49206ccc0668c3f777640bbe38fd96 424 PANTHER PTHR22777 64 412 2.0E-94 T 22-04-2016 L21SP4_RS04650 9a49206ccc0668c3f777640bbe38fd96 424 SMART SM01091 339 418 3.9E-26 T 22-04-2016 IPR005170 Transporter-associated domain L21SP4_RS04650 9a49206ccc0668c3f777640bbe38fd96 424 SMART SM00116 276 324 9.4 T 22-04-2016 IPR000644 CBS domain L21SP4_RS04650 9a49206ccc0668c3f777640bbe38fd96 424 SMART SM00116 213 262 0.018 T 22-04-2016 IPR000644 CBS domain L21SP4_RS04650 9a49206ccc0668c3f777640bbe38fd96 424 SUPERFAMILY SSF54631 199 341 1.26E-31 T 22-04-2016 L21SP4_RS04650 9a49206ccc0668c3f777640bbe38fd96 424 Pfam PF03471 Transporter associated domain 340 416 1.1E-19 T 22-04-2016 IPR005170 Transporter-associated domain L21SP4_RS04650 9a49206ccc0668c3f777640bbe38fd96 424 Gene3D G3DSA:3.30.465.10 319 415 1.1E-24 T 22-04-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 L21SP4_RS04650 9a49206ccc0668c3f777640bbe38fd96 424 Pfam PF01595 Domain of unknown function DUF21 15 189 9.2E-12 T 22-04-2016 IPR002550 Domain of unknown function DUF21 L21SP4_RS00665 fd272c7e3b88d4bd5a126511c0255fe4 462 ProSitePatterns PS00523 Sulfatases signature 1. 72 84 - T 22-04-2016 IPR024607 Sulfatase, conserved site L21SP4_RS00665 fd272c7e3b88d4bd5a126511c0255fe4 462 Pfam PF00884 Sulfatase 28 334 2.2E-72 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS00665 fd272c7e3b88d4bd5a126511c0255fe4 462 Gene3D G3DSA:3.30.1120.10 347 435 4.0E-14 T 22-04-2016 L21SP4_RS00665 fd272c7e3b88d4bd5a126511c0255fe4 462 PANTHER PTHR10342 1 445 2.3E-144 T 22-04-2016 L21SP4_RS00665 fd272c7e3b88d4bd5a126511c0255fe4 462 Gene3D G3DSA:3.40.720.10 25 346 5.8E-109 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS00665 fd272c7e3b88d4bd5a126511c0255fe4 462 SUPERFAMILY SSF53649 26 440 8.51E-124 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS00665 fd272c7e3b88d4bd5a126511c0255fe4 462 ProSitePatterns PS00149 Sulfatases signature 2. 120 130 - T 22-04-2016 IPR024607 Sulfatase, conserved site L21SP4_RS07485 c1f1bbf64b697c8fe89d5da1b9f7e31b 640 SUPERFAMILY SSF52540 355 568 1.46E-39 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS07485 c1f1bbf64b697c8fe89d5da1b9f7e31b 640 SUPERFAMILY SSF52540 133 245 1.46E-39 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS07485 c1f1bbf64b697c8fe89d5da1b9f7e31b 640 Pfam PF05872 Bacterial protein of unknown function (DUF853) 440 552 3.3E-6 T 22-04-2016 IPR033186 Helicase HerA-like C-terminal L21SP4_RS07485 c1f1bbf64b697c8fe89d5da1b9f7e31b 640 Gene3D G3DSA:3.40.50.300 400 569 3.0E-31 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS07485 c1f1bbf64b697c8fe89d5da1b9f7e31b 640 Gene3D G3DSA:3.40.50.300 111 223 3.0E-31 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS07485 c1f1bbf64b697c8fe89d5da1b9f7e31b 640 PANTHER PTHR30121 76 291 5.8E-56 T 22-04-2016 L21SP4_RS07485 c1f1bbf64b697c8fe89d5da1b9f7e31b 640 PANTHER PTHR30121 318 625 5.8E-56 T 22-04-2016 L21SP4_RS07485 c1f1bbf64b697c8fe89d5da1b9f7e31b 640 Pfam PF01935 Domain of unknown function DUF87 134 436 3.0E-44 T 22-04-2016 IPR002789 Helicase HerA, central domain L21SP4_RS06230 c48d6f28d9adc37e0e5ad11f18cb4e2e 315 SMART SM00363 21 85 9.5E-9 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 L21SP4_RS06230 c48d6f28d9adc37e0e5ad11f18cb4e2e 315 SUPERFAMILY SSF55120 78 310 3.29E-76 T 22-04-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 L21SP4_RS06230 c48d6f28d9adc37e0e5ad11f18cb4e2e 315 Pfam PF01479 S4 domain 22 67 1.3E-8 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 L21SP4_RS06230 c48d6f28d9adc37e0e5ad11f18cb4e2e 315 PANTHER PTHR11079:SF73 11 315 7.0E-114 T 22-04-2016 L21SP4_RS06230 c48d6f28d9adc37e0e5ad11f18cb4e2e 315 Gene3D G3DSA:3.10.290.10 21 72 3.1E-7 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 L21SP4_RS06230 c48d6f28d9adc37e0e5ad11f18cb4e2e 315 Pfam PF00849 RNA pseudouridylate synthase 94 249 3.9E-34 T 22-04-2016 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 L21SP4_RS06230 c48d6f28d9adc37e0e5ad11f18cb4e2e 315 SUPERFAMILY SSF55174 21 71 7.85E-9 T 22-04-2016 L21SP4_RS06230 c48d6f28d9adc37e0e5ad11f18cb4e2e 315 PANTHER PTHR11079 11 315 7.0E-114 T 22-04-2016 L21SP4_RS06230 c48d6f28d9adc37e0e5ad11f18cb4e2e 315 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 140 154 - T 22-04-2016 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 L21SP4_RS06230 c48d6f28d9adc37e0e5ad11f18cb4e2e 315 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 20 310 1.4E-87 T 22-04-2016 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 L21SP4_RS00135 9dc816e387a1cb390f7b50412c13816c 867 PRINTS PR00980 Alanyl-tRNA synthetase signature 197 208 2.0E-29 T 22-04-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 L21SP4_RS00135 9dc816e387a1cb390f7b50412c13816c 867 PRINTS PR00980 Alanyl-tRNA synthetase signature 296 309 2.0E-29 T 22-04-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 L21SP4_RS00135 9dc816e387a1cb390f7b50412c13816c 867 PRINTS PR00980 Alanyl-tRNA synthetase signature 224 237 2.0E-29 T 22-04-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 L21SP4_RS00135 9dc816e387a1cb390f7b50412c13816c 867 PRINTS PR00980 Alanyl-tRNA synthetase signature 74 85 2.0E-29 T 22-04-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 L21SP4_RS00135 9dc816e387a1cb390f7b50412c13816c 867 PRINTS PR00980 Alanyl-tRNA synthetase signature 272 288 2.0E-29 T 22-04-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 L21SP4_RS00135 9dc816e387a1cb390f7b50412c13816c 867 Pfam PF01411 tRNA synthetases class II (A) 5 543 1.3E-202 T 22-04-2016 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 L21SP4_RS00135 9dc816e387a1cb390f7b50412c13816c 867 PANTHER PTHR11777 1 865 0.0 T 22-04-2016 L21SP4_RS00135 9dc816e387a1cb390f7b50412c13816c 867 Pfam PF02272 DHHA1 domain 788 855 1.9E-10 T 22-04-2016 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7 L21SP4_RS00135 9dc816e387a1cb390f7b50412c13816c 867 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 5 843 3.0E-270 T 22-04-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 L21SP4_RS00135 9dc816e387a1cb390f7b50412c13816c 867 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 641 684 2.0E-16 T 22-04-2016 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 L21SP4_RS00135 9dc816e387a1cb390f7b50412c13816c 867 SUPERFAMILY SSF55681 2 243 1.99E-100 T 22-04-2016 L21SP4_RS00135 9dc816e387a1cb390f7b50412c13816c 867 SUPERFAMILY SSF55186 543 691 5.89E-45 T 22-04-2016 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 L21SP4_RS00135 9dc816e387a1cb390f7b50412c13816c 867 SUPERFAMILY SSF50447 454 539 5.3E-15 T 22-04-2016 IPR009000 Translation protein, beta-barrel domain L21SP4_RS00135 9dc816e387a1cb390f7b50412c13816c 867 Gene3D G3DSA:3.30.930.10 1 239 3.4E-113 T 22-04-2016 L21SP4_RS00135 9dc816e387a1cb390f7b50412c13816c 867 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 864 162.602 T 22-04-2016 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 L21SP4_RS00135 9dc816e387a1cb390f7b50412c13816c 867 PANTHER PTHR11777:SF9 1 865 0.0 T 22-04-2016 L21SP4_RS00135 9dc816e387a1cb390f7b50412c13816c 867 SMART SM00863 641 684 5.3E-19 T 22-04-2016 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 L21SP4_RS00135 9dc816e387a1cb390f7b50412c13816c 867 SUPERFAMILY SSF101353 244 447 5.23E-62 T 22-04-2016 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7|Reactome: REACT_71 L21SP4_RS11935 140bb6757b355d2249c04b370577f6ff 578 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 266 471 1.8E-42 T 22-04-2016 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 L21SP4_RS11935 140bb6757b355d2249c04b370577f6ff 578 SUPERFAMILY SSF55681 183 467 2.39E-90 T 22-04-2016 L21SP4_RS11935 140bb6757b355d2249c04b370577f6ff 578 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 110 159 1.6E-13 T 22-04-2016 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 L21SP4_RS11935 140bb6757b355d2249c04b370577f6ff 578 Pfam PF03129 Anticodon binding domain 483 572 1.8E-19 T 22-04-2016 IPR004154 Anticodon-binding L21SP4_RS11935 140bb6757b355d2249c04b370577f6ff 578 PRINTS PR01047 Threonyl-tRNA synthetase signature 476 488 1.7E-52 T 22-04-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 L21SP4_RS11935 140bb6757b355d2249c04b370577f6ff 578 PRINTS PR01047 Threonyl-tRNA synthetase signature 304 327 1.7E-52 T 22-04-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 L21SP4_RS11935 140bb6757b355d2249c04b370577f6ff 578 PRINTS PR01047 Threonyl-tRNA synthetase signature 449 462 1.7E-52 T 22-04-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 L21SP4_RS11935 140bb6757b355d2249c04b370577f6ff 578 PRINTS PR01047 Threonyl-tRNA synthetase signature 271 299 1.7E-52 T 22-04-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 L21SP4_RS11935 140bb6757b355d2249c04b370577f6ff 578 PRINTS PR01047 Threonyl-tRNA synthetase signature 406 434 1.7E-52 T 22-04-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 L21SP4_RS11935 140bb6757b355d2249c04b370577f6ff 578 Gene3D G3DSA:3.40.50.800 473 577 5.2E-31 T 22-04-2016 IPR004154 Anticodon-binding L21SP4_RS11935 140bb6757b355d2249c04b370577f6ff 578 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 7 576 33.449 T 22-04-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 L21SP4_RS11935 140bb6757b355d2249c04b370577f6ff 578 SUPERFAMILY SSF52954 471 574 7.1E-29 T 22-04-2016 IPR004154 Anticodon-binding L21SP4_RS11935 140bb6757b355d2249c04b370577f6ff 578 SMART SM00863 110 159 1.8E-19 T 22-04-2016 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 L21SP4_RS11935 140bb6757b355d2249c04b370577f6ff 578 Gene3D G3DSA:3.30.980.10 7 70 5.0E-35 T 22-04-2016 L21SP4_RS11935 140bb6757b355d2249c04b370577f6ff 578 Gene3D G3DSA:3.30.980.10 128 163 5.0E-35 T 22-04-2016 L21SP4_RS11935 140bb6757b355d2249c04b370577f6ff 578 SUPERFAMILY SSF55186 6 181 3.14E-60 T 22-04-2016 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 L21SP4_RS11935 140bb6757b355d2249c04b370577f6ff 578 Gene3D G3DSA:3.30.54.20 71 127 9.3E-24 T 22-04-2016 L21SP4_RS11935 140bb6757b355d2249c04b370577f6ff 578 Gene3D G3DSA:3.30.930.10 182 471 3.6E-111 T 22-04-2016 L21SP4_RS11935 140bb6757b355d2249c04b370577f6ff 578 PANTHER PTHR11451:SF5 7 578 2.6E-262 T 22-04-2016 L21SP4_RS11935 140bb6757b355d2249c04b370577f6ff 578 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 13 573 3.9E-217 T 22-04-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 L21SP4_RS11935 140bb6757b355d2249c04b370577f6ff 578 PANTHER PTHR11451 7 578 2.6E-262 T 22-04-2016 L21SP4_RS10285 1acea0d5082617851987e4851427df02 357 Hamap MF_00354 Isopentenyl-diphosphate delta-isomerase [fni]. 4 342 35.556 T 22-04-2016 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 L21SP4_RS10285 1acea0d5082617851987e4851427df02 357 SUPERFAMILY SSF51395 27 340 4.48E-63 T 22-04-2016 L21SP4_RS10285 1acea0d5082617851987e4851427df02 357 Gene3D G3DSA:3.20.20.70 27 333 1.9E-99 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP4_RS10285 1acea0d5082617851987e4851427df02 357 Pfam PF01070 FMN-dependent dehydrogenase 176 331 5.2E-14 T 22-04-2016 IPR000262 FMN-dependent dehydrogenase GO:0016491 L21SP4_RS10285 1acea0d5082617851987e4851427df02 357 Pfam PF01070 FMN-dependent dehydrogenase 9 97 7.7E-8 T 22-04-2016 IPR000262 FMN-dependent dehydrogenase GO:0016491 L21SP4_RS10285 1acea0d5082617851987e4851427df02 357 PANTHER PTHR10578 1 223 6.8E-95 T 22-04-2016 L21SP4_RS10285 1acea0d5082617851987e4851427df02 357 PANTHER PTHR10578 245 342 6.8E-95 T 22-04-2016 L21SP4_RS10285 1acea0d5082617851987e4851427df02 357 TIGRFAM TIGR02151 IPP_isom_2: isopentenyl-diphosphate delta-isomerase, type 2 6 333 3.1E-103 T 22-04-2016 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 L21SP4_RS10285 1acea0d5082617851987e4851427df02 357 PIRSF PIRSF003314 1 345 3.4E-109 T 22-04-2016 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 L21SP4_RS10285 1acea0d5082617851987e4851427df02 357 PANTHER PTHR10578:SF3 1 223 6.8E-95 T 22-04-2016 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 L21SP4_RS10285 1acea0d5082617851987e4851427df02 357 PANTHER PTHR10578:SF3 245 342 6.8E-95 T 22-04-2016 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 L21SP4_RS08565 44e9f030e290c67d7c1d42f8a147e7b0 367 SMART SM00382 29 212 3.5E-10 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS08565 44e9f030e290c67d7c1d42f8a147e7b0 367 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 L21SP4_RS08565 44e9f030e290c67d7c1d42f8a147e7b0 367 Pfam PF08402 TOBE domain 284 358 3.1E-7 T 22-04-2016 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 L21SP4_RS08565 44e9f030e290c67d7c1d42f8a147e7b0 367 SUPERFAMILY SSF52540 4 243 4.11E-85 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS08565 44e9f030e290c67d7c1d42f8a147e7b0 367 PANTHER PTHR24220 5 367 7.5E-168 T 22-04-2016 L21SP4_RS08565 44e9f030e290c67d7c1d42f8a147e7b0 367 SUPERFAMILY SSF50331 237 366 3.4E-25 T 22-04-2016 IPR008995 Molybdate/tungstate binding, C-terminal L21SP4_RS08565 44e9f030e290c67d7c1d42f8a147e7b0 367 Pfam PF00005 ABC transporter 21 162 3.3E-27 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 L21SP4_RS08565 44e9f030e290c67d7c1d42f8a147e7b0 367 Gene3D G3DSA:2.40.50.100 352 366 2.0E-17 T 22-04-2016 L21SP4_RS08565 44e9f030e290c67d7c1d42f8a147e7b0 367 Gene3D G3DSA:2.40.50.100 240 287 2.0E-17 T 22-04-2016 L21SP4_RS08565 44e9f030e290c67d7c1d42f8a147e7b0 367 Gene3D G3DSA:3.40.50.300 4 235 1.8E-72 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS08565 44e9f030e290c67d7c1d42f8a147e7b0 367 PANTHER PTHR24220:SF151 5 367 7.5E-168 T 22-04-2016 L21SP4_RS08565 44e9f030e290c67d7c1d42f8a147e7b0 367 Gene3D G3DSA:2.40.50.140 288 350 1.2E-14 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold L21SP4_RS04880 08093c3d9e9a66abb478c3188c160fa0 435 PANTHER PTHR30619 104 426 2.1E-39 T 22-04-2016 L21SP4_RS04880 08093c3d9e9a66abb478c3188c160fa0 435 Pfam PF03772 Competence protein 134 403 4.0E-53 T 22-04-2016 IPR004477 ComEC/Rec2-related protein L21SP4_RS04880 08093c3d9e9a66abb478c3188c160fa0 435 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 156 336 3.3E-22 T 22-04-2016 IPR004477 ComEC/Rec2-related protein L21SP4_RS06235 896bd9d5a687478e76798c0a1fe3c252 197 SUPERFAMILY SSF52141 7 189 2.71E-59 T 22-04-2016 IPR005122 Uracil-DNA glycosylase-like L21SP4_RS06235 896bd9d5a687478e76798c0a1fe3c252 197 Gene3D G3DSA:3.40.470.10 6 189 1.1E-69 T 22-04-2016 IPR005122 Uracil-DNA glycosylase-like L21SP4_RS06235 896bd9d5a687478e76798c0a1fe3c252 197 SMART SM00986 31 182 3.9E-42 T 22-04-2016 IPR005122 Uracil-DNA glycosylase-like L21SP4_RS06235 896bd9d5a687478e76798c0a1fe3c252 197 TIGRFAM TIGR00758 UDG_fam4: uracil-DNA glycosylase, family 4 17 186 6.3E-56 T 22-04-2016 IPR005273 Uracil-DNA glycosylase, family 4 domain L21SP4_RS06235 896bd9d5a687478e76798c0a1fe3c252 197 SMART SM00987 31 182 3.9E-42 T 22-04-2016 L21SP4_RS06235 896bd9d5a687478e76798c0a1fe3c252 197 PANTHER PTHR33693 7 196 3.5E-76 T 22-04-2016 L21SP4_RS06235 896bd9d5a687478e76798c0a1fe3c252 197 Pfam PF03167 Uracil DNA glycosylase superfamily 31 182 1.2E-43 T 22-04-2016 IPR005122 Uracil-DNA glycosylase-like L21SP4_RS06235 896bd9d5a687478e76798c0a1fe3c252 197 PANTHER PTHR33693:SF1 7 196 3.5E-76 T 22-04-2016 L21SP4_RS11225 a725104690130ffcd36ca5572aeb515b 395 Pfam PF13692 Glycosyl transferases group 1 248 355 1.2E-8 T 22-04-2016 L21SP4_RS11225 a725104690130ffcd36ca5572aeb515b 395 PANTHER PTHR12526 121 392 6.8E-12 T 22-04-2016 L21SP4_RS11225 a725104690130ffcd36ca5572aeb515b 395 SUPERFAMILY SSF53756 59 390 2.11E-26 T 22-04-2016 L21SP4_RS06275 3cf4c9d7b7cf8404c39741ba9d451d90 444 SUPERFAMILY SSF89550 45 113 3.92E-9 T 22-04-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 L21SP4_RS06275 3cf4c9d7b7cf8404c39741ba9d451d90 444 SUPERFAMILY SSF89550 256 346 3.92E-9 T 22-04-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 L21SP4_RS06275 3cf4c9d7b7cf8404c39741ba9d451d90 444 Gene3D G3DSA:3.20.20.140 245 346 9.1E-6 T 22-04-2016 L21SP4_RS06275 3cf4c9d7b7cf8404c39741ba9d451d90 444 Gene3D G3DSA:3.20.20.140 45 132 9.1E-6 T 22-04-2016 L21SP4_RS00315 1e06b771677d400bf1138d5e583af1ab 714 Pfam PF11987 Translation-initiation factor 2 509 604 4.0E-34 T 22-04-2016 IPR023115 Translation initiation factor IF- 2, domain 3 L21SP4_RS00315 1e06b771677d400bf1138d5e583af1ab 714 Gene3D G3DSA:2.40.30.10 386 478 1.3E-18 T 22-04-2016 L21SP4_RS00315 1e06b771677d400bf1138d5e583af1ab 714 SUPERFAMILY SSF50447 387 468 2.83E-20 T 22-04-2016 IPR009000 Translation protein, beta-barrel domain L21SP4_RS00315 1e06b771677d400bf1138d5e583af1ab 714 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 114 710 2.3E-210 T 22-04-2016 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 L21SP4_RS00315 1e06b771677d400bf1138d5e583af1ab 714 PRINTS PR00315 GTP-binding elongation factor signature 282 293 1.5E-9 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 L21SP4_RS00315 1e06b771677d400bf1138d5e583af1ab 714 PRINTS PR00315 GTP-binding elongation factor signature 318 327 1.5E-9 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 L21SP4_RS00315 1e06b771677d400bf1138d5e583af1ab 714 PRINTS PR00315 GTP-binding elongation factor signature 214 227 1.5E-9 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 L21SP4_RS00315 1e06b771677d400bf1138d5e583af1ab 714 PRINTS PR00315 GTP-binding elongation factor signature 266 276 1.5E-9 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 L21SP4_RS00315 1e06b771677d400bf1138d5e583af1ab 714 SUPERFAMILY SSF52540 208 375 1.54E-47 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS00315 1e06b771677d400bf1138d5e583af1ab 714 PANTHER PTHR23115:SF184 567 710 9.5E-180 T 22-04-2016 L21SP4_RS00315 1e06b771677d400bf1138d5e583af1ab 714 PANTHER PTHR23115:SF184 195 542 9.5E-180 T 22-04-2016 L21SP4_RS00315 1e06b771677d400bf1138d5e583af1ab 714 PANTHER PTHR23115 567 710 9.5E-180 T 22-04-2016 L21SP4_RS00315 1e06b771677d400bf1138d5e583af1ab 714 PANTHER PTHR23115 195 542 9.5E-180 T 22-04-2016 L21SP4_RS00315 1e06b771677d400bf1138d5e583af1ab 714 SUPERFAMILY SSF52156 494 621 6.54E-36 T 22-04-2016 IPR023115 Translation initiation factor IF- 2, domain 3 L21SP4_RS00315 1e06b771677d400bf1138d5e583af1ab 714 Gene3D G3DSA:3.30.56.50 2 41 1.9E-4 T 22-04-2016 L21SP4_RS00315 1e06b771677d400bf1138d5e583af1ab 714 Gene3D G3DSA:2.40.30.10 616 711 3.2E-31 T 22-04-2016 L21SP4_RS00315 1e06b771677d400bf1138d5e583af1ab 714 SUPERFAMILY SSF50447 616 709 3.79E-25 T 22-04-2016 IPR009000 Translation protein, beta-barrel domain L21SP4_RS00315 1e06b771677d400bf1138d5e583af1ab 714 Pfam PF00009 Elongation factor Tu GTP binding domain 215 374 8.9E-33 T 22-04-2016 L21SP4_RS00315 1e06b771677d400bf1138d5e583af1ab 714 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 2 712 15.47 T 22-04-2016 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 L21SP4_RS00315 1e06b771677d400bf1138d5e583af1ab 714 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 121 170 3.1E-10 T 22-04-2016 IPR006847 Translation initiation factor IF-2, N-terminal L21SP4_RS00315 1e06b771677d400bf1138d5e583af1ab 714 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 1 48 4.6E-8 T 22-04-2016 IPR006847 Translation initiation factor IF-2, N-terminal L21SP4_RS00315 1e06b771677d400bf1138d5e583af1ab 714 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 213 370 1.9E-29 T 22-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 L21SP4_RS00315 1e06b771677d400bf1138d5e583af1ab 714 Gene3D G3DSA:3.40.50.300 211 373 6.0E-45 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS00315 1e06b771677d400bf1138d5e583af1ab 714 Gene3D G3DSA:3.40.50.10050 515 593 4.7E-24 T 22-04-2016 IPR023115 Translation initiation factor IF- 2, domain 3 L21SP4_RS03085 084c28963de3a89a62990b5d65dddc9f 181 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 121 149 - T 22-04-2016 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: REACT_17015 L21SP4_RS03085 084c28963de3a89a62990b5d65dddc9f 181 Gene3D G3DSA:2.160.10.10 31 169 2.2E-38 T 22-04-2016 L21SP4_RS03085 084c28963de3a89a62990b5d65dddc9f 181 SUPERFAMILY SSF51161 12 168 2.08E-39 T 22-04-2016 IPR011004 Trimeric LpxA-like L21SP4_RS03085 084c28963de3a89a62990b5d65dddc9f 181 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 112 147 2.8E-9 T 22-04-2016 IPR001451 Hexapeptide repeat L21SP4_RS03085 084c28963de3a89a62990b5d65dddc9f 181 PANTHER PTHR23416 16 173 7.8E-34 T 22-04-2016 L21SP4_RS01190 1bd4696901d0b11cb7999978fe008a77 446 Pfam PF03441 FAD binding domain of DNA photolyase 269 441 2.1E-71 T 22-04-2016 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain L21SP4_RS01190 1bd4696901d0b11cb7999978fe008a77 446 PANTHER PTHR11455:SF18 5 445 4.0E-171 T 22-04-2016 L21SP4_RS01190 1bd4696901d0b11cb7999978fe008a77 446 SUPERFAMILY SSF48173 191 445 8.11E-100 T 22-04-2016 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain L21SP4_RS01190 1bd4696901d0b11cb7999978fe008a77 446 PRINTS PR00147 DNA photolyase signature 318 334 2.3E-24 T 22-04-2016 IPR002081 Cryptochrome/DNA photolyase class 1 L21SP4_RS01190 1bd4696901d0b11cb7999978fe008a77 446 PRINTS PR00147 DNA photolyase signature 338 356 2.3E-24 T 22-04-2016 IPR002081 Cryptochrome/DNA photolyase class 1 L21SP4_RS01190 1bd4696901d0b11cb7999978fe008a77 446 PRINTS PR00147 DNA photolyase signature 138 154 2.3E-24 T 22-04-2016 IPR002081 Cryptochrome/DNA photolyase class 1 L21SP4_RS01190 1bd4696901d0b11cb7999978fe008a77 446 PRINTS PR00147 DNA photolyase signature 377 391 2.3E-24 T 22-04-2016 IPR002081 Cryptochrome/DNA photolyase class 1 L21SP4_RS01190 1bd4696901d0b11cb7999978fe008a77 446 ProSitePatterns PS00691 DNA photolyases class 1 signature 2. 338 357 - T 22-04-2016 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal L21SP4_RS01190 1bd4696901d0b11cb7999978fe008a77 446 PANTHER PTHR11455 5 445 4.0E-171 T 22-04-2016 L21SP4_RS01190 1bd4696901d0b11cb7999978fe008a77 446 Gene3D G3DSA:3.40.50.620 4 161 1.4E-40 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP4_RS01190 1bd4696901d0b11cb7999978fe008a77 446 Pfam PF00875 DNA photolyase 6 162 2.1E-41 T 22-04-2016 IPR006050 DNA photolyase, N-terminal L21SP4_RS01190 1bd4696901d0b11cb7999978fe008a77 446 Gene3D G3DSA:1.10.579.10 278 445 5.7E-67 T 22-04-2016 L21SP4_RS01190 1bd4696901d0b11cb7999978fe008a77 446 SUPERFAMILY SSF52425 5 167 1.06E-45 T 22-04-2016 IPR006050 DNA photolyase, N-terminal L21SP4_RS01190 1bd4696901d0b11cb7999978fe008a77 446 ProSitePatterns PS00394 DNA photolyases class 1 signature 1. 318 330 - T 22-04-2016 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal L21SP4_RS01190 1bd4696901d0b11cb7999978fe008a77 446 Gene3D G3DSA:1.25.40.80 195 277 2.4E-40 T 22-04-2016 L21SP4_RS11145 a7087236b7a74adea8084d41c7b44099 132 Pfam PF05168 HEPN domain 6 128 6.4E-20 T 22-04-2016 IPR007842 HEPN domain L21SP4_RS11145 a7087236b7a74adea8084d41c7b44099 132 Gene3D G3DSA:1.20.120.330 4 130 1.2E-23 T 22-04-2016 L21SP4_RS11145 a7087236b7a74adea8084d41c7b44099 132 SUPERFAMILY SSF81593 5 129 6.28E-17 T 22-04-2016 L21SP4_RS11145 a7087236b7a74adea8084d41c7b44099 132 SMART SM00748 9 122 7.0E-5 T 22-04-2016 IPR007842 HEPN domain L21SP4_RS06165 7f9c9df04ed26d05b0aee100183c0d05 472 ProSitePatterns PS00163 Fumarate lyases signature. 281 290 - T 22-04-2016 IPR020557 Fumarate lyase, conserved site GO:0003824 L21SP4_RS06165 7f9c9df04ed26d05b0aee100183c0d05 472 Pfam PF00206 Lyase 52 300 7.0E-47 T 22-04-2016 IPR022761 Fumarate lyase, N-terminal L21SP4_RS06165 7f9c9df04ed26d05b0aee100183c0d05 472 PRINTS PR00149 Fumarate lyase superfamily signature 107 125 1.6E-20 T 22-04-2016 IPR000362 Fumarate lyase family L21SP4_RS06165 7f9c9df04ed26d05b0aee100183c0d05 472 PRINTS PR00149 Fumarate lyase superfamily signature 152 170 1.6E-20 T 22-04-2016 IPR000362 Fumarate lyase family L21SP4_RS06165 7f9c9df04ed26d05b0aee100183c0d05 472 PRINTS PR00149 Fumarate lyase superfamily signature 281 297 1.6E-20 T 22-04-2016 IPR000362 Fumarate lyase family L21SP4_RS06165 7f9c9df04ed26d05b0aee100183c0d05 472 PRINTS PR00149 Fumarate lyase superfamily signature 237 264 1.6E-20 T 22-04-2016 IPR000362 Fumarate lyase family L21SP4_RS06165 7f9c9df04ed26d05b0aee100183c0d05 472 Hamap MF_00006 Argininosuccinate lyase [argH]. 5 431 28.712 T 22-04-2016 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 L21SP4_RS06165 7f9c9df04ed26d05b0aee100183c0d05 472 PRINTS PR00145 Argininosuccinate lyase family signature 106 128 6.5E-38 T 22-04-2016 L21SP4_RS06165 7f9c9df04ed26d05b0aee100183c0d05 472 PRINTS PR00145 Argininosuccinate lyase family signature 281 297 6.5E-38 T 22-04-2016 L21SP4_RS06165 7f9c9df04ed26d05b0aee100183c0d05 472 PRINTS PR00145 Argininosuccinate lyase family signature 237 261 6.5E-38 T 22-04-2016 L21SP4_RS06165 7f9c9df04ed26d05b0aee100183c0d05 472 PRINTS PR00145 Argininosuccinate lyase family signature 198 214 6.5E-38 T 22-04-2016 L21SP4_RS06165 7f9c9df04ed26d05b0aee100183c0d05 472 PRINTS PR00145 Argininosuccinate lyase family signature 147 167 6.5E-38 T 22-04-2016 L21SP4_RS06165 7f9c9df04ed26d05b0aee100183c0d05 472 PRINTS PR00145 Argininosuccinate lyase family signature 316 335 6.5E-38 T 22-04-2016 L21SP4_RS06165 7f9c9df04ed26d05b0aee100183c0d05 472 Gene3D G3DSA:1.10.275.10 19 111 2.2E-18 T 22-04-2016 IPR024083 Fumarase/histidase, N-terminal L21SP4_RS06165 7f9c9df04ed26d05b0aee100183c0d05 472 TIGRFAM TIGR00838 argH: argininosuccinate lyase 11 392 6.2E-91 T 22-04-2016 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 L21SP4_RS06165 7f9c9df04ed26d05b0aee100183c0d05 472 PANTHER PTHR11444 8 392 3.9E-107 T 22-04-2016 IPR000362 Fumarate lyase family L21SP4_RS06165 7f9c9df04ed26d05b0aee100183c0d05 472 SUPERFAMILY SSF48557 22 398 2.04E-92 T 22-04-2016 IPR008948 L-Aspartase-like GO:0003824 L21SP4_RS06165 7f9c9df04ed26d05b0aee100183c0d05 472 PANTHER PTHR11444:SF3 8 392 3.9E-107 T 22-04-2016 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 L21SP4_RS06165 7f9c9df04ed26d05b0aee100183c0d05 472 Gene3D G3DSA:1.20.200.10 112 389 8.3E-67 T 22-04-2016 L21SP4_RS05845 1d8b3297d9ddb48c43c73ebe8297d89c 366 Gene3D G3DSA:3.40.50.2000 143 338 8.7E-31 T 22-04-2016 L21SP4_RS05845 1d8b3297d9ddb48c43c73ebe8297d89c 366 PANTHER PTHR12526 1 361 4.7E-63 T 22-04-2016 L21SP4_RS05845 1d8b3297d9ddb48c43c73ebe8297d89c 366 Pfam PF13439 Glycosyltransferase Family 4 13 161 1.2E-30 T 22-04-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain L21SP4_RS05845 1d8b3297d9ddb48c43c73ebe8297d89c 366 Pfam PF00534 Glycosyl transferases group 1 177 333 2.1E-32 T 22-04-2016 IPR001296 Glycosyl transferase, family 1 L21SP4_RS05845 1d8b3297d9ddb48c43c73ebe8297d89c 366 SUPERFAMILY SSF53756 3 361 1.92E-81 T 22-04-2016 L21SP4_RS05095 2c5103bab0d92fe2b2958551021f0522 751 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 62 704 3.5E-135 T 22-04-2016 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 L21SP4_RS05095 2c5103bab0d92fe2b2958551021f0522 751 SUPERFAMILY SSF50249 522 618 1.99E-123 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold L21SP4_RS05095 2c5103bab0d92fe2b2958551021f0522 751 PANTHER PTHR23355 73 729 1.9E-161 T 22-04-2016 L21SP4_RS05095 2c5103bab0d92fe2b2958551021f0522 751 Pfam PF00773 RNB domain 252 573 7.7E-95 T 22-04-2016 L21SP4_RS05095 2c5103bab0d92fe2b2958551021f0522 751 Gene3D G3DSA:2.40.50.140 628 703 3.8E-8 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold L21SP4_RS05095 2c5103bab0d92fe2b2958551021f0522 751 Hamap MF_01895 Ribonuclease R [rnr]. 26 706 42.311 T 22-04-2016 IPR011805 Ribonuclease R GO:0003723|GO:0004518 L21SP4_RS05095 2c5103bab0d92fe2b2958551021f0522 751 SUPERFAMILY SSF50249 56 138 2.14E-6 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold L21SP4_RS05095 2c5103bab0d92fe2b2958551021f0522 751 SMART SM00955 252 576 9.6E-128 T 22-04-2016 L21SP4_RS05095 2c5103bab0d92fe2b2958551021f0522 751 ProSitePatterns PS01175 Ribonuclease II family signature. 543 567 - T 22-04-2016 IPR022966 Ribonuclease II/R, conserved site L21SP4_RS05095 2c5103bab0d92fe2b2958551021f0522 751 SUPERFAMILY SSF50249 628 700 4.9E-9 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold L21SP4_RS05095 2c5103bab0d92fe2b2958551021f0522 751 SUPERFAMILY SSF50249 180 489 1.99E-123 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold L21SP4_RS05095 2c5103bab0d92fe2b2958551021f0522 751 PANTHER PTHR23355:SF9 73 729 1.9E-161 T 22-04-2016 L21SP4_RS09130 e24574206c02eb1e5ff47fb5eee06544 409 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 179 371 1.7E-5 T 22-04-2016 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: REACT_11193|UniPathway: UPA00253 L21SP4_RS09130 e24574206c02eb1e5ff47fb5eee06544 409 Gene3D G3DSA:3.20.20.70 172 374 2.0E-43 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP4_RS09130 e24574206c02eb1e5ff47fb5eee06544 409 SUPERFAMILY SSF54675 134 179 8.37E-18 T 22-04-2016 L21SP4_RS09130 e24574206c02eb1e5ff47fb5eee06544 409 SUPERFAMILY SSF54675 17 75 8.37E-18 T 22-04-2016 L21SP4_RS09130 e24574206c02eb1e5ff47fb5eee06544 409 PIRSF PIRSF000484 22 395 1.1E-46 T 22-04-2016 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|UniPathway: UPA00253 L21SP4_RS09130 e24574206c02eb1e5ff47fb5eee06544 409 SUPERFAMILY SSF51690 176 402 2.21E-43 T 22-04-2016 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: REACT_11193|UniPathway: UPA00253 L21SP4_RS09130 e24574206c02eb1e5ff47fb5eee06544 409 Gene3D G3DSA:3.90.1170.20 11 75 3.4E-13 T 22-04-2016 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 L21SP4_RS09130 e24574206c02eb1e5ff47fb5eee06544 409 Gene3D G3DSA:3.90.1170.20 134 170 3.4E-13 T 22-04-2016 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 L21SP4_RS07870 e9df0992d83fc548bed7e54030f5ff2e 787 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 16 166 2.2E-13 T 22-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 L21SP4_RS07870 e9df0992d83fc548bed7e54030f5ff2e 787 Pfam PF07664 Ferrous iron transport protein B C terminus 469 521 1.8E-22 T 22-04-2016 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 L21SP4_RS07870 e9df0992d83fc548bed7e54030f5ff2e 787 PANTHER PTHR11649:SF37 276 625 1.0E-263 T 22-04-2016 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 L21SP4_RS07870 e9df0992d83fc548bed7e54030f5ff2e 787 PANTHER PTHR11649:SF37 692 759 1.0E-263 T 22-04-2016 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 L21SP4_RS07870 e9df0992d83fc548bed7e54030f5ff2e 787 PANTHER PTHR11649:SF37 1 157 1.0E-263 T 22-04-2016 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 L21SP4_RS07870 e9df0992d83fc548bed7e54030f5ff2e 787 Pfam PF07670 Nucleoside recognition 366 457 7.3E-15 T 22-04-2016 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: REACT_15518|Reactome: REACT_1698 L21SP4_RS07870 e9df0992d83fc548bed7e54030f5ff2e 787 Pfam PF07670 Nucleoside recognition 527 723 6.3E-32 T 22-04-2016 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: REACT_15518|Reactome: REACT_1698 L21SP4_RS07870 e9df0992d83fc548bed7e54030f5ff2e 787 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 21 721 6.5E-191 T 22-04-2016 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 L21SP4_RS07870 e9df0992d83fc548bed7e54030f5ff2e 787 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 17 37 5.16E-5 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 L21SP4_RS07870 e9df0992d83fc548bed7e54030f5ff2e 787 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 65 80 5.16E-5 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 L21SP4_RS07870 e9df0992d83fc548bed7e54030f5ff2e 787 SUPERFAMILY SSF52540 15 174 7.25E-44 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS07870 e9df0992d83fc548bed7e54030f5ff2e 787 PANTHER PTHR11649 276 625 1.0E-263 T 22-04-2016 L21SP4_RS07870 e9df0992d83fc548bed7e54030f5ff2e 787 PANTHER PTHR11649 692 759 1.0E-263 T 22-04-2016 L21SP4_RS07870 e9df0992d83fc548bed7e54030f5ff2e 787 PANTHER PTHR11649 1 157 1.0E-263 T 22-04-2016 L21SP4_RS07870 e9df0992d83fc548bed7e54030f5ff2e 787 Pfam PF02421 Ferrous iron transport protein B 16 170 2.7E-65 T 22-04-2016 IPR011619 Ferrous iron transport protein B, N-terminal GO:0005525|GO:0015093|GO:0015684|GO:0016021 L21SP4_RS07870 e9df0992d83fc548bed7e54030f5ff2e 787 Gene3D G3DSA:3.40.50.300 14 180 3.8E-37 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS07495 ae68e1fe3e5860924d9ff2a3094a9518 996 Gene3D G3DSA:3.40.50.300 268 474 3.6E-17 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS07495 ae68e1fe3e5860924d9ff2a3094a9518 996 SUPERFAMILY SSF52540 459 481 8.49E-23 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS07495 ae68e1fe3e5860924d9ff2a3094a9518 996 SUPERFAMILY SSF52540 237 419 8.49E-23 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS07495 ae68e1fe3e5860924d9ff2a3094a9518 996 SMART SM00487 271 492 3.8E-11 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain L21SP4_RS07495 ae68e1fe3e5860924d9ff2a3094a9518 996 Pfam PF04851 Type III restriction enzyme, res subunit 275 471 8.5E-14 T 22-04-2016 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 L21SP4_RS07495 ae68e1fe3e5860924d9ff2a3094a9518 996 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 8 209 2.5E-17 T 22-04-2016 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 L21SP4_RS07495 ae68e1fe3e5860924d9ff2a3094a9518 996 PANTHER PTHR30195 5 422 0.0 T 22-04-2016 L21SP4_RS07495 ae68e1fe3e5860924d9ff2a3094a9518 996 PANTHER PTHR30195 449 929 0.0 T 22-04-2016 L21SP4_RS07495 ae68e1fe3e5860924d9ff2a3094a9518 996 PANTHER PTHR30195:SF13 5 422 0.0 T 22-04-2016 L21SP4_RS07495 ae68e1fe3e5860924d9ff2a3094a9518 996 PANTHER PTHR30195:SF13 449 929 0.0 T 22-04-2016 L21SP4_RS05375 665ca961f3f1f892fe47c2d939423f4c 228 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 37 214 1.1E-32 T 22-04-2016 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 L21SP4_RS05375 665ca961f3f1f892fe47c2d939423f4c 228 SUPERFAMILY SSF100950 4 224 6.42E-32 T 22-04-2016 L21SP4_RS05375 665ca961f3f1f892fe47c2d939423f4c 228 Gene3D G3DSA:3.40.50.1360 4 224 3.3E-36 T 22-04-2016 L21SP4_RS05375 665ca961f3f1f892fe47c2d939423f4c 228 PANTHER PTHR11054 38 209 2.1E-20 T 22-04-2016 L21SP4_RS09040 fe2066096086654f2930e5833d5346ab 892 Hamap MF_02004 Valine--tRNA ligase [valS]. 6 890 15.19 T 22-04-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 L21SP4_RS09040 fe2066096086654f2930e5833d5346ab 892 SUPERFAMILY SSF46589 825 887 1.31E-12 T 22-04-2016 IPR010978 tRNA-binding arm GO:0000166 Reactome: REACT_71 L21SP4_RS09040 fe2066096086654f2930e5833d5346ab 892 PRINTS PR00986 Valyl-tRNA synthetase signature 233 250 1.6E-32 T 22-04-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 L21SP4_RS09040 fe2066096086654f2930e5833d5346ab 892 PRINTS PR00986 Valyl-tRNA synthetase signature 446 467 1.6E-32 T 22-04-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 L21SP4_RS09040 fe2066096086654f2930e5833d5346ab 892 PRINTS PR00986 Valyl-tRNA synthetase signature 348 361 1.6E-32 T 22-04-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 L21SP4_RS09040 fe2066096086654f2930e5833d5346ab 892 PRINTS PR00986 Valyl-tRNA synthetase signature 39 50 1.6E-32 T 22-04-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 L21SP4_RS09040 fe2066096086654f2930e5833d5346ab 892 PRINTS PR00986 Valyl-tRNA synthetase signature 477 495 1.6E-32 T 22-04-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 L21SP4_RS09040 fe2066096086654f2930e5833d5346ab 892 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 19 564 9.5E-199 T 22-04-2016 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 L21SP4_RS09040 fe2066096086654f2930e5833d5346ab 892 PANTHER PTHR11946 821 883 0.0 T 22-04-2016 L21SP4_RS09040 fe2066096086654f2930e5833d5346ab 892 PANTHER PTHR11946 1 801 0.0 T 22-04-2016 L21SP4_RS09040 fe2066096086654f2930e5833d5346ab 892 Gene3D G3DSA:1.10.730.10 564 755 5.4E-50 T 22-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 L21SP4_RS09040 fe2066096086654f2930e5833d5346ab 892 SUPERFAMILY SSF50677 194 343 1.15E-58 T 22-04-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Reactome: REACT_71 L21SP4_RS09040 fe2066096086654f2930e5833d5346ab 892 Gene3D G3DSA:3.90.740.10 198 339 1.6E-46 T 22-04-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Reactome: REACT_71 L21SP4_RS09040 fe2066096086654f2930e5833d5346ab 892 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 825 886 1.5E-14 T 22-04-2016 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 L21SP4_RS09040 fe2066096086654f2930e5833d5346ab 892 Gene3D G3DSA:3.40.50.620 343 562 1.8E-142 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP4_RS09040 fe2066096086654f2930e5833d5346ab 892 Gene3D G3DSA:3.40.50.620 8 196 1.8E-142 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP4_RS09040 fe2066096086654f2930e5833d5346ab 892 TIGRFAM TIGR00422 valS: valine--tRNA ligase 6 870 0.0 T 22-04-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 L21SP4_RS09040 fe2066096086654f2930e5833d5346ab 892 SUPERFAMILY SSF52374 4 195 7.11E-142 T 22-04-2016 L21SP4_RS09040 fe2066096086654f2930e5833d5346ab 892 SUPERFAMILY SSF52374 343 570 7.11E-142 T 22-04-2016 L21SP4_RS09040 fe2066096086654f2930e5833d5346ab 892 Gene3D G3DSA:1.10.287.380 818 880 3.7E-8 T 22-04-2016 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 L21SP4_RS09040 fe2066096086654f2930e5833d5346ab 892 PANTHER PTHR11946:SF5 821 883 0.0 T 22-04-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 L21SP4_RS09040 fe2066096086654f2930e5833d5346ab 892 PANTHER PTHR11946:SF5 1 801 0.0 T 22-04-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 L21SP4_RS09040 fe2066096086654f2930e5833d5346ab 892 Pfam PF08264 Anticodon-binding domain of tRNA 611 762 6.4E-40 T 22-04-2016 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 Reactome: REACT_71 L21SP4_RS09040 fe2066096086654f2930e5833d5346ab 892 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 46 57 - T 22-04-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 L21SP4_RS09040 fe2066096086654f2930e5833d5346ab 892 SUPERFAMILY SSF47323 577 839 1.33E-54 T 22-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 L21SP4_RS07815 14b62b60833b8d39cc2552ea0c4dfa0e 178 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 8 29 2.6E-5 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site L21SP4_RS07815 14b62b60833b8d39cc2552ea0c4dfa0e 178 Gene3D G3DSA:3.30.700.10 10 49 6.7E-4 T 22-04-2016 L21SP4_RS07815 14b62b60833b8d39cc2552ea0c4dfa0e 178 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 8 28 - T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site L21SP4_RS07815 14b62b60833b8d39cc2552ea0c4dfa0e 178 SUPERFAMILY SSF54523 10 102 7.77E-11 T 22-04-2016 L21SP4_RS07815 14b62b60833b8d39cc2552ea0c4dfa0e 178 SUPERFAMILY SSF54523 131 162 7.77E-11 T 22-04-2016 L21SP4_RS02940 26bbb2cdf2573512e1dfcfa6e3ec1119 277 PANTHER PTHR24322 10 191 8.8E-30 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS02940 26bbb2cdf2573512e1dfcfa6e3ec1119 277 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 254 3.9E-55 T 22-04-2016 L21SP4_RS02940 26bbb2cdf2573512e1dfcfa6e3ec1119 277 PANTHER PTHR24322:SF317 10 191 8.8E-30 T 22-04-2016 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321|UniPathway: UPA00094 L21SP4_RS02940 26bbb2cdf2573512e1dfcfa6e3ec1119 277 PIRSF PIRSF000094 1 261 2.8E-61 T 22-04-2016 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321|UniPathway: UPA00094 L21SP4_RS02940 26bbb2cdf2573512e1dfcfa6e3ec1119 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 2.2E-6 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS02940 26bbb2cdf2573512e1dfcfa6e3ec1119 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 2.2E-6 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS02940 26bbb2cdf2573512e1dfcfa6e3ec1119 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 2.2E-6 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS02940 26bbb2cdf2573512e1dfcfa6e3ec1119 277 Gene3D G3DSA:3.40.50.720 5 256 1.5E-43 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS02940 26bbb2cdf2573512e1dfcfa6e3ec1119 277 SUPERFAMILY SSF51735 5 256 5.61E-42 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS06960 aa9e865e63ea89ba0d139ec867178f34 1267 Pfam PF00884 Sulfatase 22 378 5.1E-48 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS06960 aa9e865e63ea89ba0d139ec867178f34 1267 PANTHER PTHR12872:SF1 557 1267 1.4E-181 T 22-04-2016 L21SP4_RS06960 aa9e865e63ea89ba0d139ec867178f34 1267 ProSitePatterns PS00523 Sulfatases signature 1. 67 79 - T 22-04-2016 IPR024607 Sulfatase, conserved site L21SP4_RS06960 aa9e865e63ea89ba0d139ec867178f34 1267 Gene3D G3DSA:3.40.720.10 20 398 1.5E-87 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS06960 aa9e865e63ea89ba0d139ec867178f34 1267 SUPERFAMILY SSF53649 20 499 2.47E-112 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS06960 aa9e865e63ea89ba0d139ec867178f34 1267 Gene3D G3DSA:3.30.1120.10 427 500 2.3E-13 T 22-04-2016 L21SP4_RS06960 aa9e865e63ea89ba0d139ec867178f34 1267 PANTHER PTHR12872 557 1267 1.4E-181 T 22-04-2016 IPR007781 Alpha-N-acetylglucosaminidase KEGG: 00531+3.2.1.50 L21SP4_RS06960 aa9e865e63ea89ba0d139ec867178f34 1267 Pfam PF05089 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain 661 989 3.2E-100 T 22-04-2016 IPR024733 Alpha-N-acetylglucosaminidase, tim-barrel domain KEGG: 00531+3.2.1.50 L21SP4_RS06960 aa9e865e63ea89ba0d139ec867178f34 1267 Pfam PF12972 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain 1003 1259 1.2E-61 T 22-04-2016 IPR024732 Alpha-N-acetylglucosaminidase, C-terminal KEGG: 00531+3.2.1.50 L21SP4_RS06960 aa9e865e63ea89ba0d139ec867178f34 1267 Pfam PF12971 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain 567 646 6.0E-19 T 22-04-2016 IPR024240 Alpha-N-acetylglucosaminidase, N-terminal KEGG: 00531+3.2.1.50 L21SP4_RS06090 3f6ce35d42630c4f3b22150f617e076a 470 PANTHER PTHR22572 168 275 4.5E-16 T 22-04-2016 L21SP4_RS06090 3f6ce35d42630c4f3b22150f617e076a 470 Gene3D G3DSA:2.160.10.10 197 272 3.4E-12 T 22-04-2016 L21SP4_RS06090 3f6ce35d42630c4f3b22150f617e076a 470 SUPERFAMILY SSF51161 191 269 3.33E-13 T 22-04-2016 IPR011004 Trimeric LpxA-like L21SP4_RS06090 3f6ce35d42630c4f3b22150f617e076a 470 SUPERFAMILY SSF53448 19 257 1.05E-12 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases L21SP4_RS06090 3f6ce35d42630c4f3b22150f617e076a 470 Gene3D G3DSA:3.90.550.10 19 76 1.5E-7 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases L21SP4_RS06090 3f6ce35d42630c4f3b22150f617e076a 470 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 218 250 7.3E-8 T 22-04-2016 IPR001451 Hexapeptide repeat L21SP4_RS01605 7b939e671f84a16748d37cf523ff11d4 301 PANTHER PTHR30193 14 300 6.9E-106 T 22-04-2016 L21SP4_RS01605 7b939e671f84a16748d37cf523ff11d4 301 SUPERFAMILY SSF161098 61 287 9.94E-59 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 L21SP4_RS01605 7b939e671f84a16748d37cf523ff11d4 301 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 288 9.2E-17 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 L21SP4_RS01605 7b939e671f84a16748d37cf523ff11d4 301 Gene3D G3DSA:1.10.3720.10 69 295 1.0E-60 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 L21SP4_RS01605 7b939e671f84a16748d37cf523ff11d4 301 PANTHER PTHR30193:SF1 14 300 6.9E-106 T 22-04-2016 L21SP4_RS05335 8a2ac7eada7d8c0e9df695d91816ea51 311 PANTHER PTHR30566 65 289 5.6E-23 T 22-04-2016 L21SP4_RS05335 8a2ac7eada7d8c0e9df695d91816ea51 311 Gene3D G3DSA:3.30.70.100 186 280 4.6E-7 T 22-04-2016 L21SP4_RS05335 8a2ac7eada7d8c0e9df695d91816ea51 311 SUPERFAMILY SSF82689 182 294 1.96E-7 T 22-04-2016 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 L21SP4_RS05335 8a2ac7eada7d8c0e9df695d91816ea51 311 SUPERFAMILY SSF50182 103 177 9.48E-12 T 22-04-2016 IPR010920 LSM domain L21SP4_RS05335 8a2ac7eada7d8c0e9df695d91816ea51 311 Pfam PF00924 Mechanosensitive ion channel 66 278 4.6E-31 T 22-04-2016 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 L21SP4_RS05335 8a2ac7eada7d8c0e9df695d91816ea51 311 Gene3D G3DSA:2.30.30.60 118 176 4.5E-11 T 22-04-2016 L21SP4_RS05335 8a2ac7eada7d8c0e9df695d91816ea51 311 PANTHER PTHR30566:SF14 65 289 5.6E-23 T 22-04-2016 L21SP4_RS11100 c57311ebc7d4da6a55ac03c9190cdfd5 404 Gene3D G3DSA:3.40.50.2000 185 369 1.9E-24 T 22-04-2016 L21SP4_RS11100 c57311ebc7d4da6a55ac03c9190cdfd5 404 PANTHER PTHR12526 1 400 1.5E-63 T 22-04-2016 L21SP4_RS11100 c57311ebc7d4da6a55ac03c9190cdfd5 404 Pfam PF13439 Glycosyltransferase Family 4 15 190 2.2E-26 T 22-04-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain L21SP4_RS11100 c57311ebc7d4da6a55ac03c9190cdfd5 404 Pfam PF00534 Glycosyl transferases group 1 205 369 1.3E-25 T 22-04-2016 IPR001296 Glycosyl transferase, family 1 L21SP4_RS11100 c57311ebc7d4da6a55ac03c9190cdfd5 404 SUPERFAMILY SSF53756 2 389 9.42E-75 T 22-04-2016 L21SP4_RS08425 f2804bdc73f60f1aaa5d03e6620554e2 124 SUPERFAMILY SSF50249 2 123 5.05E-52 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold L21SP4_RS08425 f2804bdc73f60f1aaa5d03e6620554e2 124 ProSitePatterns PS00055 Ribosomal protein S12 signature. 43 50 - T 22-04-2016 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS08425 f2804bdc73f60f1aaa5d03e6620554e2 124 Pfam PF00164 Ribosomal protein S12/S23 3 123 2.9E-43 T 22-04-2016 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS08425 f2804bdc73f60f1aaa5d03e6620554e2 124 PRINTS PR01034 Ribosomal protein S12 signature 58 77 3.9E-58 T 22-04-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 L21SP4_RS08425 f2804bdc73f60f1aaa5d03e6620554e2 124 PRINTS PR01034 Ribosomal protein S12 signature 94 110 3.9E-58 T 22-04-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 L21SP4_RS08425 f2804bdc73f60f1aaa5d03e6620554e2 124 PRINTS PR01034 Ribosomal protein S12 signature 110 122 3.9E-58 T 22-04-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 L21SP4_RS08425 f2804bdc73f60f1aaa5d03e6620554e2 124 PRINTS PR01034 Ribosomal protein S12 signature 27 42 3.9E-58 T 22-04-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 L21SP4_RS08425 f2804bdc73f60f1aaa5d03e6620554e2 124 PRINTS PR01034 Ribosomal protein S12 signature 77 94 3.9E-58 T 22-04-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 L21SP4_RS08425 f2804bdc73f60f1aaa5d03e6620554e2 124 PRINTS PR01034 Ribosomal protein S12 signature 42 57 3.9E-58 T 22-04-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 L21SP4_RS08425 f2804bdc73f60f1aaa5d03e6620554e2 124 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 123 6.8E-67 T 22-04-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 L21SP4_RS08425 f2804bdc73f60f1aaa5d03e6620554e2 124 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 123 39.327 T 22-04-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 L21SP4_RS08425 f2804bdc73f60f1aaa5d03e6620554e2 124 PANTHER PTHR11652 1 116 1.3E-71 T 22-04-2016 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS08425 f2804bdc73f60f1aaa5d03e6620554e2 124 PIRSF PIRSF002133 1 124 3.9E-55 T 22-04-2016 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS08425 f2804bdc73f60f1aaa5d03e6620554e2 124 Gene3D G3DSA:2.40.50.140 1 123 1.8E-64 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold L21SP4_RS10355 746c76591f96416a2c0c554ea2da3962 409 PANTHER PTHR30489 7 409 4.5E-74 T 22-04-2016 L21SP4_RS10355 746c76591f96416a2c0c554ea2da3962 409 Pfam PF12704 MacB-like periplasmic core domain 25 238 5.4E-16 T 22-04-2016 IPR025857 MacB-like periplasmic core domain L21SP4_RS10355 746c76591f96416a2c0c554ea2da3962 409 Pfam PF02687 FtsX-like permease family 269 402 2.7E-17 T 22-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 L21SP4_RS06825 d3a2445170c3b2ac1f40da19cae28f20 197 SUPERFAMILY SSF54211 89 181 1.23E-30 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold L21SP4_RS06825 d3a2445170c3b2ac1f40da19cae28f20 197 Gene3D G3DSA:3.30.230.40 4 91 1.1E-34 T 22-04-2016 L21SP4_RS06825 d3a2445170c3b2ac1f40da19cae28f20 197 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 158 170 - T 22-04-2016 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19|UniPathway: UPA00031 L21SP4_RS06825 d3a2445170c3b2ac1f40da19cae28f20 197 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 33 176 1.1E-56 T 22-04-2016 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19|UniPathway: UPA00031 L21SP4_RS06825 d3a2445170c3b2ac1f40da19cae28f20 197 PANTHER PTHR23133 1 197 2.0E-89 T 22-04-2016 L21SP4_RS06825 d3a2445170c3b2ac1f40da19cae28f20 197 Gene3D G3DSA:3.30.230.40 92 196 4.7E-25 T 22-04-2016 L21SP4_RS06825 d3a2445170c3b2ac1f40da19cae28f20 197 SUPERFAMILY SSF54211 4 87 1.13E-30 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold L21SP4_RS06825 d3a2445170c3b2ac1f40da19cae28f20 197 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 63 76 - T 22-04-2016 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19|UniPathway: UPA00031 L21SP4_RS06825 d3a2445170c3b2ac1f40da19cae28f20 197 PANTHER PTHR23133:SF2 1 197 2.0E-89 T 22-04-2016 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19|UniPathway: UPA00031 L21SP4_RS06825 d3a2445170c3b2ac1f40da19cae28f20 197 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 4 197 39.702 T 22-04-2016 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19|UniPathway: UPA00031 L21SP4_RS09260 0ea09a9c75bac9802ef6cc0af0e7cb87 179 PANTHER PTHR30093 1 82 4.7E-22 T 22-04-2016 L21SP4_RS09260 0ea09a9c75bac9802ef6cc0af0e7cb87 179 PANTHER PTHR30093 101 145 4.7E-22 T 22-04-2016 L21SP4_RS09260 0ea09a9c75bac9802ef6cc0af0e7cb87 179 Pfam PF13544 Type IV pilin N-term methylation site GFxxxE 7 32 5.3E-8 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site L21SP4_RS09260 0ea09a9c75bac9802ef6cc0af0e7cb87 179 PRINTS PR00813 Bacterial general secretion pathway protein G signature 12 37 5.1E-9 T 22-04-2016 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 L21SP4_RS09260 0ea09a9c75bac9802ef6cc0af0e7cb87 179 PRINTS PR00813 Bacterial general secretion pathway protein G signature 48 66 5.1E-9 T 22-04-2016 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 L21SP4_RS09260 0ea09a9c75bac9802ef6cc0af0e7cb87 179 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 11 33 1.8E-7 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site L21SP4_RS09260 0ea09a9c75bac9802ef6cc0af0e7cb87 179 Gene3D G3DSA:3.30.700.10 13 81 1.3E-10 T 22-04-2016 L21SP4_RS09260 0ea09a9c75bac9802ef6cc0af0e7cb87 179 SUPERFAMILY SSF54523 13 138 4.03E-18 T 22-04-2016 L21SP4_RS01960 a0e53436ff6277b5a8ed37bf1f195ebd 240 Pfam PF02811 PHP domain 6 99 3.6E-9 T 22-04-2016 IPR004013 PHP domain GO:0003824 L21SP4_RS01960 a0e53436ff6277b5a8ed37bf1f195ebd 240 Gene3D G3DSA:3.20.20.140 3 87 1.2E-23 T 22-04-2016 L21SP4_RS01960 a0e53436ff6277b5a8ed37bf1f195ebd 240 Gene3D G3DSA:3.20.20.140 121 212 1.2E-23 T 22-04-2016 L21SP4_RS01960 a0e53436ff6277b5a8ed37bf1f195ebd 240 SUPERFAMILY SSF89550 128 236 4.9E-31 T 22-04-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 L21SP4_RS01960 a0e53436ff6277b5a8ed37bf1f195ebd 240 SUPERFAMILY SSF89550 2 83 4.9E-31 T 22-04-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 L21SP4_RS01960 a0e53436ff6277b5a8ed37bf1f195ebd 240 Pfam PF13263 PHP-associated 190 231 7.8E-9 T 22-04-2016 L21SP4_RS01960 a0e53436ff6277b5a8ed37bf1f195ebd 240 SMART SM00481 5 73 2.0E-11 T 22-04-2016 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 L21SP4_RS01255 58f4a343a07cb5c79834e26f3888043e 75 TIGRFAM TIGR02574 stabl_TIGR02574: putative addiction module component, TIGR02574 family 11 72 2.7E-11 T 22-04-2016 IPR013406 Conserved hypothetical protein CHP02574, addiction module L21SP4_RS01255 58f4a343a07cb5c79834e26f3888043e 75 Pfam PF09720 Putative addiction module component 13 65 2.5E-18 T 22-04-2016 IPR013406 Conserved hypothetical protein CHP02574, addiction module L21SP4_RS06645 eaa59bc7817acb1e167965973f905f6c 325 SMART SM00829 16 315 1.5E-6 T 22-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 L21SP4_RS06645 eaa59bc7817acb1e167965973f905f6c 325 PANTHER PTHR11695:SF38 18 325 6.3E-69 T 22-04-2016 L21SP4_RS06645 eaa59bc7817acb1e167965973f905f6c 325 Gene3D G3DSA:3.90.180.10 6 143 4.3E-33 T 22-04-2016 IPR011032 GroES-like L21SP4_RS06645 eaa59bc7817acb1e167965973f905f6c 325 Gene3D G3DSA:3.40.50.720 144 258 1.9E-30 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS06645 eaa59bc7817acb1e167965973f905f6c 325 SUPERFAMILY SSF50129 5 117 3.54E-35 T 22-04-2016 IPR011032 GroES-like L21SP4_RS06645 eaa59bc7817acb1e167965973f905f6c 325 SUPERFAMILY SSF50129 290 317 3.54E-35 T 22-04-2016 IPR011032 GroES-like L21SP4_RS06645 eaa59bc7817acb1e167965973f905f6c 325 SUPERFAMILY SSF51735 127 265 1.62E-30 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS06645 eaa59bc7817acb1e167965973f905f6c 325 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 31 93 1.3E-11 T 22-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 L21SP4_RS06645 eaa59bc7817acb1e167965973f905f6c 325 PANTHER PTHR11695 18 325 6.3E-69 T 22-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 L21SP4_RS06645 eaa59bc7817acb1e167965973f905f6c 325 Pfam PF00107 Zinc-binding dehydrogenase 150 281 6.3E-19 T 22-04-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 L21SP4_RS06645 eaa59bc7817acb1e167965973f905f6c 325 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 64 78 - T 22-04-2016 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 L21SP4_RS09140 6c82d472b681997c10e0a61d0f04a221 654 Gene3D G3DSA:3.90.1390.10 475 515 5.8E-9 T 22-04-2016 L21SP4_RS09140 6c82d472b681997c10e0a61d0f04a221 654 Gene3D G3DSA:3.90.1390.10 593 651 5.8E-9 T 22-04-2016 L21SP4_RS09140 6c82d472b681997c10e0a61d0f04a221 654 SUPERFAMILY SSF51998 22 622 3.05E-89 T 22-04-2016 L21SP4_RS09140 6c82d472b681997c10e0a61d0f04a221 654 Gene3D G3DSA:3.20.70.20 178 474 3.6E-62 T 22-04-2016 L21SP4_RS09140 6c82d472b681997c10e0a61d0f04a221 654 Gene3D G3DSA:3.20.70.20 11 125 3.6E-62 T 22-04-2016 L21SP4_RS09140 6c82d472b681997c10e0a61d0f04a221 654 Gene3D G3DSA:3.20.70.20 550 592 3.6E-62 T 22-04-2016 L21SP4_RS05010 2a3a243bc01788d3dbd0884110762b35 510 Hamap MF_01571 Proline--tRNA ligase [proS]. 11 510 42.438 T 22-04-2016 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 L21SP4_RS05010 2a3a243bc01788d3dbd0884110762b35 510 Pfam PF03129 Anticodon binding domain 305 401 4.2E-12 T 22-04-2016 IPR004154 Anticodon-binding L21SP4_RS05010 2a3a243bc01788d3dbd0884110762b35 510 PANTHER PTHR11451:SF6 15 482 7.5E-213 T 22-04-2016 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 L21SP4_RS05010 2a3a243bc01788d3dbd0884110762b35 510 Gene3D G3DSA:3.30.930.10 11 297 1.7E-102 T 22-04-2016 L21SP4_RS05010 2a3a243bc01788d3dbd0884110762b35 510 SMART SM00946 443 510 1.3E-20 T 22-04-2016 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 L21SP4_RS05010 2a3a243bc01788d3dbd0884110762b35 510 SUPERFAMILY SSF55681 15 291 1.36E-67 T 22-04-2016 L21SP4_RS05010 2a3a243bc01788d3dbd0884110762b35 510 Gene3D G3DSA:3.40.50.800 298 423 5.5E-31 T 22-04-2016 IPR004154 Anticodon-binding L21SP4_RS05010 2a3a243bc01788d3dbd0884110762b35 510 TIGRFAM TIGR00408 proS_fam_I: proline--tRNA ligase 14 510 8.0E-149 T 22-04-2016 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 L21SP4_RS05010 2a3a243bc01788d3dbd0884110762b35 510 SUPERFAMILY SSF52954 293 425 8.91E-25 T 22-04-2016 IPR004154 Anticodon-binding L21SP4_RS05010 2a3a243bc01788d3dbd0884110762b35 510 SUPERFAMILY SSF64586 441 510 3.34E-17 T 22-04-2016 IPR017449 Prolyl-tRNA synthetase, class II GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 L21SP4_RS05010 2a3a243bc01788d3dbd0884110762b35 510 Gene3D G3DSA:3.30.110.30 427 509 3.7E-22 T 22-04-2016 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 L21SP4_RS05010 2a3a243bc01788d3dbd0884110762b35 510 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 118 282 3.1E-12 T 22-04-2016 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 L21SP4_RS05010 2a3a243bc01788d3dbd0884110762b35 510 Pfam PF09180 Prolyl-tRNA synthetase, C-terminal 452 510 1.7E-16 T 22-04-2016 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 L21SP4_RS05010 2a3a243bc01788d3dbd0884110762b35 510 PANTHER PTHR11451 15 482 7.5E-213 T 22-04-2016 L21SP4_RS11005 e32a1b63a22e412f4487174f01fe02b8 262 PANTHER PTHR36445:SF1 1 254 1.6E-81 T 22-04-2016 L21SP4_RS11005 e32a1b63a22e412f4487174f01fe02b8 262 Pfam PF02649 Type I GTP cyclohydrolase folE2 1 254 9.5E-98 T 22-04-2016 IPR003801 GTP cyclohydrolase FolE2/MptA GO:0003933 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 L21SP4_RS11005 e32a1b63a22e412f4487174f01fe02b8 262 Gene3D G3DSA:3.10.270.10 1 257 3.0E-107 T 22-04-2016 L21SP4_RS11005 e32a1b63a22e412f4487174f01fe02b8 262 Hamap MF_01527_B GTP cyclohydrolase FolE2 [folE2]. 1 259 37.413 T 22-04-2016 IPR022838 GTP cyclohydrolase FolE2 GO:0003934|GO:0035998 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 L21SP4_RS11005 e32a1b63a22e412f4487174f01fe02b8 262 TIGRFAM TIGR00294 TIGR00294: GTP cyclohydrolase 149 254 5.1E-30 T 22-04-2016 IPR003801 GTP cyclohydrolase FolE2/MptA GO:0003933 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 L21SP4_RS11005 e32a1b63a22e412f4487174f01fe02b8 262 PANTHER PTHR36445 1 254 1.6E-81 T 22-04-2016 L21SP4_RS01105 5a8863b0336949310ccf0796df2c44dc 325 Gene3D G3DSA:3.90.550.10 33 154 5.3E-9 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases L21SP4_RS01105 5a8863b0336949310ccf0796df2c44dc 325 SUPERFAMILY SSF53448 34 277 5.63E-47 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases L21SP4_RS01105 5a8863b0336949310ccf0796df2c44dc 325 PANTHER PTHR10859 22 212 5.0E-18 T 22-04-2016 L21SP4_RS01105 5a8863b0336949310ccf0796df2c44dc 325 Pfam PF00535 Glycosyl transferase family 2 35 128 1.1E-8 T 22-04-2016 IPR001173 Glycosyltransferase 2-like L21SP4_RS01105 5a8863b0336949310ccf0796df2c44dc 325 PANTHER PTHR10859:SF99 22 212 5.0E-18 T 22-04-2016 L21SP4_RS07755 5f2891f8bf2ec2fb513d83168082b63d 177 PANTHER PTHR10108 3 151 1.5E-21 T 22-04-2016 L21SP4_RS07755 5f2891f8bf2ec2fb513d83168082b63d 177 Gene3D G3DSA:3.40.50.150 5 151 1.4E-24 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS07755 5f2891f8bf2ec2fb513d83168082b63d 177 Pfam PF08242 Methyltransferase domain 10 106 1.4E-16 T 22-04-2016 IPR013217 Methyltransferase type 12 L21SP4_RS07755 5f2891f8bf2ec2fb513d83168082b63d 177 SUPERFAMILY SSF53335 5 159 7.99E-30 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS06750 340c6d209c4018361717da23aea6a310 211 PANTHER PTHR30383 9 211 5.7E-27 T 22-04-2016 L21SP4_RS06750 340c6d209c4018361717da23aea6a310 211 SUPERFAMILY SSF52266 7 203 8.7E-39 T 22-04-2016 IPR013830 SGNH hydrolase-type esterase domain L21SP4_RS06750 340c6d209c4018361717da23aea6a310 211 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 13 196 3.2E-25 T 22-04-2016 IPR013830 SGNH hydrolase-type esterase domain L21SP4_RS06750 340c6d209c4018361717da23aea6a310 211 Gene3D G3DSA:3.40.50.1110 7 205 1.0E-41 T 22-04-2016 IPR013830 SGNH hydrolase-type esterase domain L21SP4_RS02960 32f81869eb9a6189828ad7eedc9c3741 181 PANTHER PTHR21087:SF0 13 172 9.9E-37 T 22-04-2016 L21SP4_RS02960 32f81869eb9a6189828ad7eedc9c3741 181 SUPERFAMILY SSF52540 12 175 4.3E-25 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS02960 32f81869eb9a6189828ad7eedc9c3741 181 PRINTS PR01100 Shikimate kinase family signature 41 54 9.6E-20 T 22-04-2016 L21SP4_RS02960 32f81869eb9a6189828ad7eedc9c3741 181 PRINTS PR01100 Shikimate kinase family signature 107 124 9.6E-20 T 22-04-2016 L21SP4_RS02960 32f81869eb9a6189828ad7eedc9c3741 181 PRINTS PR01100 Shikimate kinase family signature 86 95 9.6E-20 T 22-04-2016 L21SP4_RS02960 32f81869eb9a6189828ad7eedc9c3741 181 PRINTS PR01100 Shikimate kinase family signature 17 32 9.6E-20 T 22-04-2016 L21SP4_RS02960 32f81869eb9a6189828ad7eedc9c3741 181 PRINTS PR01100 Shikimate kinase family signature 69 77 9.6E-20 T 22-04-2016 L21SP4_RS02960 32f81869eb9a6189828ad7eedc9c3741 181 Pfam PF01202 Shikimate kinase 23 174 2.4E-38 T 22-04-2016 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163|UniPathway: UPA00053 L21SP4_RS02960 32f81869eb9a6189828ad7eedc9c3741 181 Gene3D G3DSA:3.40.50.300 14 177 6.0E-43 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS02960 32f81869eb9a6189828ad7eedc9c3741 181 PANTHER PTHR21087 13 172 9.9E-37 T 22-04-2016 L21SP4_RS02960 32f81869eb9a6189828ad7eedc9c3741 181 Hamap MF_00109 Shikimate kinase [aroK]. 14 177 22.962 T 22-04-2016 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163|UniPathway: UPA00053 L21SP4_RS03310 caf2e15ff96981b270748a44e5df57d7 113 Pfam PF03747 ADP-ribosylglycohydrolase 8 85 4.5E-18 T 22-04-2016 IPR005502 ADP-ribosylation/Crystallin J1 L21SP4_RS03310 caf2e15ff96981b270748a44e5df57d7 113 SUPERFAMILY SSF101478 3 93 9.94E-24 T 22-04-2016 IPR005502 ADP-ribosylation/Crystallin J1 L21SP4_RS03310 caf2e15ff96981b270748a44e5df57d7 113 PANTHER PTHR16222 1 84 3.4E-17 T 22-04-2016 L21SP4_RS03310 caf2e15ff96981b270748a44e5df57d7 113 PANTHER PTHR16222:SF12 1 84 3.4E-17 T 22-04-2016 L21SP4_RS11700 dbb14406dc2f167f8bb9a2ab0973cad4 786 SMART SM00640 340 748 4.2E-12 T 22-04-2016 IPR001362 Glycoside hydrolase, family 32 GO:0004553|GO:0005975 L21SP4_RS11700 dbb14406dc2f167f8bb9a2ab0973cad4 786 Pfam PF08244 Glycosyl hydrolases family 32 C terminal 686 747 1.5E-4 T 22-04-2016 IPR013189 Glycosyl hydrolase family 32, C-terminal L21SP4_RS11700 dbb14406dc2f167f8bb9a2ab0973cad4 786 SUPERFAMILY SSF49899 630 781 2.8E-9 T 22-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP4_RS11700 dbb14406dc2f167f8bb9a2ab0973cad4 786 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 155 274 4.1E-8 T 22-04-2016 L21SP4_RS11700 dbb14406dc2f167f8bb9a2ab0973cad4 786 SUPERFAMILY SSF75005 334 624 2.14E-28 T 22-04-2016 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP4_RS11700 dbb14406dc2f167f8bb9a2ab0973cad4 786 SUPERFAMILY SSF49899 99 291 6.34E-16 T 22-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP4_RS11700 dbb14406dc2f167f8bb9a2ab0973cad4 786 Gene3D G3DSA:2.115.10.20 452 504 3.9E-7 T 22-04-2016 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP4_RS11700 dbb14406dc2f167f8bb9a2ab0973cad4 786 Pfam PF00251 Glycosyl hydrolases family 32 N-terminal domain 353 625 1.4E-19 T 22-04-2016 IPR013148 Glycosyl hydrolase family 32, N-terminal L21SP4_RS11700 dbb14406dc2f167f8bb9a2ab0973cad4 786 Gene3D G3DSA:2.60.120.200 115 296 3.1E-11 T 22-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP4_RS11700 dbb14406dc2f167f8bb9a2ab0973cad4 786 Gene3D G3DSA:2.60.120.560 605 753 6.3E-18 T 22-04-2016 IPR013189 Glycosyl hydrolase family 32, C-terminal L21SP4_RS05945 5e9cdca9e699a531659041fabcf94843 917 Gene3D G3DSA:1.50.10.10 419 680 1.7E-4 T 22-04-2016 IPR012341 Six-hairpin glycosidase GO:0003824 L21SP4_RS05945 5e9cdca9e699a531659041fabcf94843 917 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 84 244 3.8E-9 T 22-04-2016 L21SP4_RS05945 5e9cdca9e699a531659041fabcf94843 917 Pfam PF07944 Beta-L-arabinofuranosidase, GH127 321 811 1.2E-42 T 22-04-2016 IPR012878 Beta-L-arabinofuranosidase, GH127 KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18 L21SP4_RS05945 5e9cdca9e699a531659041fabcf94843 917 SUPERFAMILY SSF49899 15 246 6.44E-18 T 22-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP4_RS05945 5e9cdca9e699a531659041fabcf94843 917 PANTHER PTHR31151 359 811 1.3E-32 T 22-04-2016 L21SP4_RS05945 5e9cdca9e699a531659041fabcf94843 917 Gene3D G3DSA:2.60.120.200 69 244 3.1E-10 T 22-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP4_RS05945 5e9cdca9e699a531659041fabcf94843 917 SUPERFAMILY SSF48208 347 644 1.11E-16 T 22-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP4_RS02160 9edcd9000c6c56f8675405ac5aede0b1 404 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 13 392 8.9E-145 T 22-04-2016 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 L21SP4_RS02160 9edcd9000c6c56f8675405ac5aede0b1 404 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 11 393 44.571 T 22-04-2016 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 L21SP4_RS02160 9edcd9000c6c56f8675405ac5aede0b1 404 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 218 255 - T 22-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 L21SP4_RS02160 9edcd9000c6c56f8675405ac5aede0b1 404 Gene3D G3DSA:3.90.1150.10 10 56 5.4E-33 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 L21SP4_RS02160 9edcd9000c6c56f8675405ac5aede0b1 404 Gene3D G3DSA:3.90.1150.10 302 394 5.4E-33 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 L21SP4_RS02160 9edcd9000c6c56f8675405ac5aede0b1 404 Gene3D G3DSA:3.40.640.10 57 299 5.5E-89 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 L21SP4_RS02160 9edcd9000c6c56f8675405ac5aede0b1 404 PANTHER PTHR11986:SF79 2 400 3.2E-172 T 22-04-2016 L21SP4_RS02160 9edcd9000c6c56f8675405ac5aede0b1 404 Pfam PF00202 Aminotransferase class-III 22 390 7.3E-111 T 22-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 L21SP4_RS02160 9edcd9000c6c56f8675405ac5aede0b1 404 PANTHER PTHR11986 2 400 3.2E-172 T 22-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 L21SP4_RS02160 9edcd9000c6c56f8675405ac5aede0b1 404 SUPERFAMILY SSF53383 9 394 1.18E-123 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase L21SP4_RS01610 0ec9e2a9a803372632c73b29d5ee2de9 553 PANTHER PTHR32243:SF31 328 553 2.5E-87 T 22-04-2016 IPR030165 sn-glycerol-3-phosphate transport system permease protein UgpE GO:0001407|GO:0005887|GO:0015794|GO:0055052 L21SP4_RS01610 0ec9e2a9a803372632c73b29d5ee2de9 553 Gene3D G3DSA:1.10.3720.10 328 540 1.5E-65 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 L21SP4_RS01610 0ec9e2a9a803372632c73b29d5ee2de9 553 Gene3D G3DSA:1.10.3720.10 4 51 1.5E-65 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 L21SP4_RS01610 0ec9e2a9a803372632c73b29d5ee2de9 553 SUPERFAMILY SSF161098 328 553 1.96E-62 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 L21SP4_RS01610 0ec9e2a9a803372632c73b29d5ee2de9 553 PANTHER PTHR32243 328 553 2.5E-87 T 22-04-2016 L21SP4_RS01610 0ec9e2a9a803372632c73b29d5ee2de9 553 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 372 543 1.3E-18 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 L21SP4_RS07735 39bf258d64e1c2238ddad0d90c2b0ce6 584 ProSitePatterns PS00211 ABC transporters family signature. 471 485 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 L21SP4_RS07735 39bf258d64e1c2238ddad0d90c2b0ce6 584 SMART SM00382 359 545 1.2E-17 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS07735 39bf258d64e1c2238ddad0d90c2b0ce6 584 Pfam PF00005 ABC transporter 350 499 4.6E-31 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 L21SP4_RS07735 39bf258d64e1c2238ddad0d90c2b0ce6 584 Gene3D G3DSA:3.40.50.300 335 572 1.7E-81 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS07735 39bf258d64e1c2238ddad0d90c2b0ce6 584 PANTHER PTHR24222:SF29 1 584 2.5E-285 T 22-04-2016 L21SP4_RS07735 39bf258d64e1c2238ddad0d90c2b0ce6 584 SUPERFAMILY SSF90123 21 322 3.79E-50 T 22-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 L21SP4_RS07735 39bf258d64e1c2238ddad0d90c2b0ce6 584 SUPERFAMILY SSF52540 328 569 4.42E-90 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS07735 39bf258d64e1c2238ddad0d90c2b0ce6 584 Pfam PF00664 ABC transporter transmembrane region 97 284 6.0E-23 T 22-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 L21SP4_RS07735 39bf258d64e1c2238ddad0d90c2b0ce6 584 Gene3D G3DSA:1.20.1560.10 21 324 9.6E-38 T 22-04-2016 L21SP4_RS07735 39bf258d64e1c2238ddad0d90c2b0ce6 584 PANTHER PTHR24222 1 584 2.5E-285 T 22-04-2016 L21SP4_RS08440 5a55d4c2e52d1538339634357a0953ec 122 SUPERFAMILY SSF48300 3 58 1.7E-13 T 22-04-2016 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS08440 5a55d4c2e52d1538339634357a0953ec 122 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 1 122 22.742 T 22-04-2016 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS08440 5a55d4c2e52d1538339634357a0953ec 122 Gene3D G3DSA:3.30.1390.10 51 122 2.0E-32 T 22-04-2016 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like L21SP4_RS08440 5a55d4c2e52d1538339634357a0953ec 122 Gene3D G3DSA:1.20.5.710 3 49 2.6E-15 T 22-04-2016 L21SP4_RS08440 5a55d4c2e52d1538339634357a0953ec 122 TIGRFAM TIGR00855 L12: ribosomal protein bL12 3 122 7.7E-43 T 22-04-2016 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS08440 5a55d4c2e52d1538339634357a0953ec 122 SUPERFAMILY SSF54736 52 122 3.14E-24 T 22-04-2016 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like L21SP4_RS08440 5a55d4c2e52d1538339634357a0953ec 122 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 56 122 3.4E-29 T 22-04-2016 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 L21SP4_RS08440 5a55d4c2e52d1538339634357a0953ec 122 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 3 45 1.8E-16 T 22-04-2016 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS08440 5a55d4c2e52d1538339634357a0953ec 122 PANTHER PTHR24089 1 119 1.7E-20 T 22-04-2016 L21SP4_RS08440 5a55d4c2e52d1538339634357a0953ec 122 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 57 122 3.0E-19 T 22-04-2016 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 L21SP4_RS08440 5a55d4c2e52d1538339634357a0953ec 122 PANTHER PTHR24089:SF321 1 119 1.7E-20 T 22-04-2016 L21SP4_RS11915 267efb7f725f0e3e9ca2cfbd2614c447 623 Pfam PF14574 Domain of unknown function (DUF4445) 199 614 5.7E-127 T 22-04-2016 IPR027980 Protein of unknown function DUF4445 L21SP4_RS11915 267efb7f725f0e3e9ca2cfbd2614c447 623 Gene3D G3DSA:3.10.20.30 6 91 4.9E-7 T 22-04-2016 IPR012675 Beta-grasp domain L21SP4_RS11915 267efb7f725f0e3e9ca2cfbd2614c447 623 SUPERFAMILY SSF53067 256 301 8.1E-6 T 22-04-2016 L21SP4_RS11915 267efb7f725f0e3e9ca2cfbd2614c447 623 SUPERFAMILY SSF53067 203 228 8.1E-6 T 22-04-2016 L21SP4_RS11915 267efb7f725f0e3e9ca2cfbd2614c447 623 SUPERFAMILY SSF53067 493 552 8.1E-6 T 22-04-2016 L21SP4_RS11915 267efb7f725f0e3e9ca2cfbd2614c447 623 SUPERFAMILY SSF53067 345 394 8.1E-6 T 22-04-2016 L21SP4_RS11915 267efb7f725f0e3e9ca2cfbd2614c447 623 SUPERFAMILY SSF54292 3 89 1.62E-8 T 22-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 L21SP4_RS11915 267efb7f725f0e3e9ca2cfbd2614c447 623 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 6 78 3.9E-4 T 22-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 L21SP4_RS06310 36facd64a035cac789d1cd6ad407ebb4 584 Pfam PF00425 chorismate binding enzyme 110 363 3.3E-79 T 22-04-2016 IPR015890 Chorismate-utilising enzyme, C-terminal L21SP4_RS06310 36facd64a035cac789d1cd6ad407ebb4 584 SUPERFAMILY SSF56322 32 367 1.83E-98 T 22-04-2016 IPR005801 ADC synthase GO:0009058 L21SP4_RS06310 36facd64a035cac789d1cd6ad407ebb4 584 PRINTS PR00095 Anthranilate synthase component I signature 211 224 1.5E-9 T 22-04-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 L21SP4_RS06310 36facd64a035cac789d1cd6ad407ebb4 584 PRINTS PR00095 Anthranilate synthase component I signature 225 238 1.5E-9 T 22-04-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 L21SP4_RS06310 36facd64a035cac789d1cd6ad407ebb4 584 PRINTS PR00095 Anthranilate synthase component I signature 303 317 1.5E-9 T 22-04-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 L21SP4_RS06310 36facd64a035cac789d1cd6ad407ebb4 584 PANTHER PTHR11236 85 452 3.7E-118 T 22-04-2016 L21SP4_RS06310 36facd64a035cac789d1cd6ad407ebb4 584 SUPERFAMILY SSF56752 317 574 2.35E-39 T 22-04-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 L21SP4_RS06310 36facd64a035cac789d1cd6ad407ebb4 584 Gene3D G3DSA:3.30.470.10 378 439 2.0E-4 T 22-04-2016 L21SP4_RS06310 36facd64a035cac789d1cd6ad407ebb4 584 Pfam PF01063 Amino-transferase class IV 376 574 2.2E-32 T 22-04-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 L21SP4_RS06310 36facd64a035cac789d1cd6ad407ebb4 584 Gene3D G3DSA:3.20.10.10 462 569 1.0E-31 T 22-04-2016 L21SP4_RS06310 36facd64a035cac789d1cd6ad407ebb4 584 PANTHER PTHR11236:SF18 85 452 3.7E-118 T 22-04-2016 L21SP4_RS06310 36facd64a035cac789d1cd6ad407ebb4 584 Gene3D G3DSA:3.60.120.10 29 367 3.7E-105 T 22-04-2016 IPR005801 ADC synthase GO:0009058 L21SP4_RS06310 36facd64a035cac789d1cd6ad407ebb4 584 TIGRFAM TIGR00553 pabB: aminodeoxychorismate synthase, component I 52 367 2.2E-101 T 22-04-2016 IPR005802 Para-aminobenzoate synthase, component I GO:0009396 KEGG: 00790+2.6.1.85|MetaCyc: PWY-6543|UniPathway: UPA00077 L21SP4_RS06900 cb35abdfa00463bd4f5447ba0be54ea5 88 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 7 60 5.1E-6 T 22-04-2016 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 L21SP4_RS06900 cb35abdfa00463bd4f5447ba0be54ea5 88 Pfam PF01192 RNA polymerase Rpb6 19 60 2.0E-4 T 22-04-2016 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 L21SP4_RS06900 cb35abdfa00463bd4f5447ba0be54ea5 88 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 1 63 11.082 T 22-04-2016 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 L21SP4_RS06900 cb35abdfa00463bd4f5447ba0be54ea5 88 SUPERFAMILY SSF63562 7 67 2.44E-8 T 22-04-2016 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 L21SP4_RS09600 d1809daeb3d43ae43617dc3b587aeee4 134 Pfam PF01850 PIN domain 3 126 2.1E-13 T 22-04-2016 IPR002716 PIN domain L21SP4_RS09600 d1809daeb3d43ae43617dc3b587aeee4 134 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 3 132 11.109 T 22-04-2016 IPR022907 VapC family GO:0004540 L21SP4_RS09600 d1809daeb3d43ae43617dc3b587aeee4 134 Gene3D G3DSA:3.40.50.1010 1 134 1.2E-25 T 22-04-2016 IPR029060 PIN domain-like L21SP4_RS09600 d1809daeb3d43ae43617dc3b587aeee4 134 PANTHER PTHR33653 1 134 6.9E-24 T 22-04-2016 L21SP4_RS09600 d1809daeb3d43ae43617dc3b587aeee4 134 PANTHER PTHR33653:SF1 1 134 6.9E-24 T 22-04-2016 L21SP4_RS09600 d1809daeb3d43ae43617dc3b587aeee4 134 SUPERFAMILY SSF88723 1 133 2.61E-28 T 22-04-2016 IPR029060 PIN domain-like L21SP4_RS06020 57712d121f689a7553c9a7659d4d7143 570 Gene3D G3DSA:3.20.20.80 85 380 3.2E-16 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP4_RS06020 57712d121f689a7553c9a7659d4d7143 570 SUPERFAMILY SSF51445 115 374 1.14E-12 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily L21SP4_RS06020 57712d121f689a7553c9a7659d4d7143 570 Pfam PF01229 Glycosyl hydrolases family 39 164 417 1.8E-6 T 22-04-2016 IPR000514 Glycoside hydrolase, family 39 GO:0004553|GO:0005975 L21SP4_RS09165 792c948d1588082ddcbec164c284e980 402 Pfam PF07676 WD40-like Beta Propeller Repeat 253 289 5.7E-9 T 22-04-2016 IPR011659 WD40-like Beta Propeller L21SP4_RS09165 792c948d1588082ddcbec164c284e980 402 Pfam PF07676 WD40-like Beta Propeller Repeat 208 244 0.17 T 22-04-2016 IPR011659 WD40-like Beta Propeller L21SP4_RS09165 792c948d1588082ddcbec164c284e980 402 Gene3D G3DSA:3.40.50.10070 79 126 1.5E-7 T 22-04-2016 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 L21SP4_RS09165 792c948d1588082ddcbec164c284e980 402 PANTHER PTHR36842 182 402 4.7E-25 T 22-04-2016 L21SP4_RS09165 792c948d1588082ddcbec164c284e980 402 Gene3D G3DSA:2.130.10.10 127 402 4.0E-62 T 22-04-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 L21SP4_RS09165 792c948d1588082ddcbec164c284e980 402 SUPERFAMILY SSF52964 48 136 1.44E-10 T 22-04-2016 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 L21SP4_RS09165 792c948d1588082ddcbec164c284e980 402 SUPERFAMILY SSF69304 130 402 3.4E-47 T 22-04-2016 L21SP4_RS04680 1801628c648f141df84901e387949e7e 391 Pfam PF02661 Fic/DOC family 130 234 8.8E-22 T 22-04-2016 IPR003812 Fido domain L21SP4_RS04680 1801628c648f141df84901e387949e7e 391 PIRSF PIRSF038925 14 383 5.6E-107 T 22-04-2016 IPR026287 Adenosine monophosphate-protein transferase L21SP4_RS04680 1801628c648f141df84901e387949e7e 391 PANTHER PTHR13504:SF32 20 387 7.0E-93 T 22-04-2016 L21SP4_RS04680 1801628c648f141df84901e387949e7e 391 Gene3D G3DSA:1.10.3290.10 45 298 6.0E-62 T 22-04-2016 IPR003812 Fido domain L21SP4_RS04680 1801628c648f141df84901e387949e7e 391 PANTHER PTHR13504 20 387 7.0E-93 T 22-04-2016 L21SP4_RS04680 1801628c648f141df84901e387949e7e 391 Pfam PF13784 Fic/DOC family N-terminal 43 122 2.6E-23 T 22-04-2016 IPR025758 Fic/DOC N-terminal L21SP4_RS04680 1801628c648f141df84901e387949e7e 391 SUPERFAMILY SSF140931 106 296 1.7E-46 T 22-04-2016 IPR003812 Fido domain L21SP4_RS10650 edebc19f3333ada64530f912b92becca 329 PANTHER PTHR22604:SF14 1 326 4.3E-74 T 22-04-2016 L21SP4_RS10650 edebc19f3333ada64530f912b92becca 329 Gene3D G3DSA:3.40.50.720 1 129 1.8E-38 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS10650 edebc19f3333ada64530f912b92becca 329 SUPERFAMILY SSF55347 166 295 1.5E-11 T 22-04-2016 L21SP4_RS10650 edebc19f3333ada64530f912b92becca 329 Gene3D G3DSA:3.30.360.10 130 312 2.6E-29 T 22-04-2016 L21SP4_RS10650 edebc19f3333ada64530f912b92becca 329 SUPERFAMILY SSF51735 2 133 9.08E-40 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS10650 edebc19f3333ada64530f912b92becca 329 PANTHER PTHR22604 1 326 4.3E-74 T 22-04-2016 L21SP4_RS10650 edebc19f3333ada64530f912b92becca 329 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 4 120 3.7E-28 T 22-04-2016 IPR000683 Oxidoreductase, N-terminal GO:0016491 L21SP4_RS02085 9b64c99d568cde4b3fefbdfb16fa1d40 340 SUPERFAMILY SSF51726 1 340 1.13E-29 T 22-04-2016 L21SP4_RS02085 9b64c99d568cde4b3fefbdfb16fa1d40 340 Gene3D G3DSA:3.20.20.210 1 339 1.4E-28 T 22-04-2016 L21SP4_RS02085 9b64c99d568cde4b3fefbdfb16fa1d40 340 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 149 339 1.6E-16 T 22-04-2016 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 L21SP4_RS02045 0e9b568109361d3b773099f27b1b3d3f 282 SUPERFAMILY SSF46689 234 281 5.73E-14 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS02045 0e9b568109361d3b773099f27b1b3d3f 282 Gene3D G3DSA:2.60.120.280 39 161 7.0E-9 T 22-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 L21SP4_RS02045 0e9b568109361d3b773099f27b1b3d3f 282 Pfam PF02311 AraC-like ligand binding domain 40 106 4.6E-6 T 22-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 L21SP4_RS02045 0e9b568109361d3b773099f27b1b3d3f 282 Gene3D G3DSA:1.10.10.60 235 281 9.9E-20 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS02045 0e9b568109361d3b773099f27b1b3d3f 282 PANTHER PTHR11019 41 281 9.6E-37 T 22-04-2016 L21SP4_RS02045 0e9b568109361d3b773099f27b1b3d3f 282 SUPERFAMILY SSF51215 39 148 2.22E-10 T 22-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 L21SP4_RS02045 0e9b568109361d3b773099f27b1b3d3f 282 SMART SM00342 197 280 1.3E-30 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP4_RS02045 0e9b568109361d3b773099f27b1b3d3f 282 SUPERFAMILY SSF46689 180 230 3.16E-10 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS02045 0e9b568109361d3b773099f27b1b3d3f 282 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 234 276 - T 22-04-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 L21SP4_RS02045 0e9b568109361d3b773099f27b1b3d3f 282 Pfam PF12833 Helix-turn-helix domain 203 281 1.8E-25 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP4_RS02045 0e9b568109361d3b773099f27b1b3d3f 282 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 249 264 1.0E-6 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 L21SP4_RS02045 0e9b568109361d3b773099f27b1b3d3f 282 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 264 280 1.0E-6 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 L21SP4_RS02045 0e9b568109361d3b773099f27b1b3d3f 282 Gene3D G3DSA:1.10.10.60 179 234 7.4E-14 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS07425 b562357856124893bc453accdd563c02 303 SMART SM00470 34 124 5.2E-28 T 22-04-2016 IPR003115 ParB/Sulfiredoxin L21SP4_RS07425 b562357856124893bc453accdd563c02 303 PANTHER PTHR33375:SF3 6 302 1.2E-83 T 22-04-2016 L21SP4_RS07425 b562357856124893bc453accdd563c02 303 SUPERFAMILY SSF109709 116 224 1.02E-33 T 22-04-2016 L21SP4_RS07425 b562357856124893bc453accdd563c02 303 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 31 208 1.5E-54 T 22-04-2016 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 L21SP4_RS07425 b562357856124893bc453accdd563c02 303 Pfam PF02195 ParB-like nuclease domain 36 123 3.4E-21 T 22-04-2016 IPR003115 ParB/Sulfiredoxin L21SP4_RS07425 b562357856124893bc453accdd563c02 303 PANTHER PTHR33375 6 302 1.2E-83 T 22-04-2016 L21SP4_RS07425 b562357856124893bc453accdd563c02 303 Gene3D G3DSA:3.90.1530.10 34 130 1.8E-33 T 22-04-2016 L21SP4_RS07425 b562357856124893bc453accdd563c02 303 SUPERFAMILY SSF110849 36 126 4.19E-25 T 22-04-2016 IPR003115 ParB/Sulfiredoxin L21SP4_RS03860 b6e573407dbb7ad76c87e5ddfd79bccc 93 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 8 87 1.4E-25 T 22-04-2016 IPR000032 Phosphocarrier HPr protein-like L21SP4_RS03860 b6e573407dbb7ad76c87e5ddfd79bccc 93 PANTHER PTHR33705:SF2 4 93 2.5E-32 T 22-04-2016 L21SP4_RS03860 b6e573407dbb7ad76c87e5ddfd79bccc 93 SUPERFAMILY SSF55594 8 92 1.07E-25 T 22-04-2016 IPR000032 Phosphocarrier HPr protein-like L21SP4_RS03860 b6e573407dbb7ad76c87e5ddfd79bccc 93 Pfam PF00381 PTS HPr component phosphorylation site 8 87 1.1E-26 T 22-04-2016 IPR000032 Phosphocarrier HPr protein-like L21SP4_RS03860 b6e573407dbb7ad76c87e5ddfd79bccc 93 PRINTS PR00107 Phosphocarrier protein signature 18 34 1.8E-13 T 22-04-2016 IPR000032 Phosphocarrier HPr protein-like L21SP4_RS03860 b6e573407dbb7ad76c87e5ddfd79bccc 93 PRINTS PR00107 Phosphocarrier protein signature 58 75 1.8E-13 T 22-04-2016 IPR000032 Phosphocarrier HPr protein-like L21SP4_RS03860 b6e573407dbb7ad76c87e5ddfd79bccc 93 PRINTS PR00107 Phosphocarrier protein signature 43 58 1.8E-13 T 22-04-2016 IPR000032 Phosphocarrier HPr protein-like L21SP4_RS03860 b6e573407dbb7ad76c87e5ddfd79bccc 93 PANTHER PTHR33705 4 93 2.5E-32 T 22-04-2016 L21SP4_RS03860 b6e573407dbb7ad76c87e5ddfd79bccc 93 Gene3D G3DSA:3.30.1340.10 7 92 1.6E-29 T 22-04-2016 IPR000032 Phosphocarrier HPr protein-like L21SP4_RS03860 b6e573407dbb7ad76c87e5ddfd79bccc 93 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 18 25 - T 22-04-2016 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site L21SP4_RS09930 c62c1b8206686370fffbbf59e4b543bd 159 SMART SM00344 1 107 4.9E-12 T 22-04-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 L21SP4_RS09930 c62c1b8206686370fffbbf59e4b543bd 159 Pfam PF01037 Lrp/AsnC ligand binding domain 64 138 1.8E-14 T 22-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain L21SP4_RS09930 c62c1b8206686370fffbbf59e4b543bd 159 Gene3D G3DSA:3.30.70.920 61 140 1.5E-25 T 22-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain L21SP4_RS09930 c62c1b8206686370fffbbf59e4b543bd 159 Gene3D G3DSA:1.10.10.10 3 49 8.7E-9 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS09930 c62c1b8206686370fffbbf59e4b543bd 159 SUPERFAMILY SSF54909 60 144 3.49E-17 T 22-04-2016 IPR011008 Dimeric alpha-beta barrel L21SP4_RS09930 c62c1b8206686370fffbbf59e4b543bd 159 SUPERFAMILY SSF46785 3 55 5.54E-7 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS09930 c62c1b8206686370fffbbf59e4b543bd 159 PANTHER PTHR30154:SF31 3 151 4.3E-44 T 22-04-2016 L21SP4_RS09930 c62c1b8206686370fffbbf59e4b543bd 159 PANTHER PTHR30154 3 151 4.3E-44 T 22-04-2016 L21SP4_RS01835 ff06fd10962c2a34e3afe28266bac9fa 867 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 380 746 2.3E-50 T 22-04-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 L21SP4_RS01835 ff06fd10962c2a34e3afe28266bac9fa 867 PANTHER PTHR30620:SF37 26 49 2.1E-176 T 22-04-2016 L21SP4_RS01835 ff06fd10962c2a34e3afe28266bac9fa 867 PANTHER PTHR30620:SF37 74 438 2.1E-176 T 22-04-2016 L21SP4_RS01835 ff06fd10962c2a34e3afe28266bac9fa 867 PANTHER PTHR30620:SF37 590 867 2.1E-176 T 22-04-2016 L21SP4_RS01835 ff06fd10962c2a34e3afe28266bac9fa 867 Gene3D G3DSA:3.40.50.1700 603 745 3.9E-58 T 22-04-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 L21SP4_RS01835 ff06fd10962c2a34e3afe28266bac9fa 867 Gene3D G3DSA:3.40.50.1700 366 439 3.9E-58 T 22-04-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 L21SP4_RS01835 ff06fd10962c2a34e3afe28266bac9fa 867 Pfam PF14310 Fibronectin type III-like domain 784 853 1.0E-14 T 22-04-2016 IPR026891 Fibronectin type III-like domain L21SP4_RS01835 ff06fd10962c2a34e3afe28266bac9fa 867 PRINTS PR00133 Glycosyl hydrolase family 3 signature 263 281 4.0E-14 T 22-04-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 L21SP4_RS01835 ff06fd10962c2a34e3afe28266bac9fa 867 PRINTS PR00133 Glycosyl hydrolase family 3 signature 116 135 4.0E-14 T 22-04-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 L21SP4_RS01835 ff06fd10962c2a34e3afe28266bac9fa 867 PRINTS PR00133 Glycosyl hydrolase family 3 signature 162 178 4.0E-14 T 22-04-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 L21SP4_RS01835 ff06fd10962c2a34e3afe28266bac9fa 867 Gene3D G3DSA:3.20.20.300 22 349 6.3E-85 T 22-04-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 L21SP4_RS01835 ff06fd10962c2a34e3afe28266bac9fa 867 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 34 339 6.9E-53 T 22-04-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 L21SP4_RS01835 ff06fd10962c2a34e3afe28266bac9fa 867 SMART SM01217 783 853 9.5E-17 T 22-04-2016 IPR026891 Fibronectin type III-like domain L21SP4_RS01835 ff06fd10962c2a34e3afe28266bac9fa 867 Pfam PF07691 PA14 domain 501 586 1.0E-4 T 22-04-2016 IPR011658 PA14 domain L21SP4_RS01835 ff06fd10962c2a34e3afe28266bac9fa 867 SUPERFAMILY SSF51445 22 378 5.16E-77 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily L21SP4_RS01835 ff06fd10962c2a34e3afe28266bac9fa 867 SUPERFAMILY SSF52279 606 749 9.42E-48 T 22-04-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 L21SP4_RS01835 ff06fd10962c2a34e3afe28266bac9fa 867 SUPERFAMILY SSF52279 380 445 9.42E-48 T 22-04-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 L21SP4_RS01835 ff06fd10962c2a34e3afe28266bac9fa 867 PANTHER PTHR30620 26 49 2.1E-176 T 22-04-2016 IPR026892 Glycoside hydrolase family 3 GO:0004553 L21SP4_RS01835 ff06fd10962c2a34e3afe28266bac9fa 867 PANTHER PTHR30620 74 438 2.1E-176 T 22-04-2016 IPR026892 Glycoside hydrolase family 3 GO:0004553 L21SP4_RS01835 ff06fd10962c2a34e3afe28266bac9fa 867 PANTHER PTHR30620 590 867 2.1E-176 T 22-04-2016 IPR026892 Glycoside hydrolase family 3 GO:0004553 L21SP4_RS03840 95882486c136b51934481e080bce7e83 153 Pfam PF03968 OstA-like protein 24 127 1.5E-14 T 22-04-2016 IPR005653 Organic solvent tolerance-like, N-terminal L21SP4_RS03840 95882486c136b51934481e080bce7e83 153 Gene3D G3DSA:2.60.450.10 21 135 2.3E-25 T 22-04-2016 L21SP4_RS01020 ac6c1954c5013cf6d28848066e5ded6c 214 SUPERFAMILY SSF51366 2 210 6.12E-46 T 22-04-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 L21SP4_RS01020 ac6c1954c5013cf6d28848066e5ded6c 214 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 1 213 32.247 T 22-04-2016 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24|UniPathway: UPA00035 L21SP4_RS01020 ac6c1954c5013cf6d28848066e5ded6c 214 PANTHER PTHR22854:SF6 1 208 1.1E-45 T 22-04-2016 L21SP4_RS01020 ac6c1954c5013cf6d28848066e5ded6c 214 PANTHER PTHR22854 1 208 1.1E-45 T 22-04-2016 L21SP4_RS01020 ac6c1954c5013cf6d28848066e5ded6c 214 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 3 208 1.4E-34 T 22-04-2016 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24|UniPathway: UPA00035 L21SP4_RS01020 ac6c1954c5013cf6d28848066e5ded6c 214 Gene3D G3DSA:3.20.20.70 2 211 1.8E-55 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP4_RS04290 30ba6eae473666a05ff48ff5ca694f63 294 PANTHER PTHR33376:SF2 8 292 6.1E-93 T 22-04-2016 L21SP4_RS04290 30ba6eae473666a05ff48ff5ca694f63 294 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 2 278 1.1E-81 T 22-04-2016 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 L21SP4_RS04290 30ba6eae473666a05ff48ff5ca694f63 294 PIRSF PIRSF006470 1 293 1.8E-87 T 22-04-2016 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 L21SP4_RS04290 30ba6eae473666a05ff48ff5ca694f63 294 PANTHER PTHR33376 8 292 6.1E-93 T 22-04-2016 L21SP4_RS04290 30ba6eae473666a05ff48ff5ca694f63 294 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 2 256 9.2E-70 T 22-04-2016 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 L21SP4_RS10215 dac726d04461f359b7f79d1bcc69c761 267 PANTHER PTHR13754:SF15 3 257 1.5E-69 T 22-04-2016 L21SP4_RS10215 dac726d04461f359b7f79d1bcc69c761 267 SUPERFAMILY SSF56281 9 227 1.18E-36 T 22-04-2016 IPR001279 Metallo-beta-lactamase L21SP4_RS10215 dac726d04461f359b7f79d1bcc69c761 267 Pfam PF12706 Beta-lactamase superfamily domain 24 204 1.9E-17 T 22-04-2016 IPR001279 Metallo-beta-lactamase L21SP4_RS10215 dac726d04461f359b7f79d1bcc69c761 267 Gene3D G3DSA:3.60.15.10 10 248 1.4E-31 T 22-04-2016 IPR001279 Metallo-beta-lactamase L21SP4_RS10215 dac726d04461f359b7f79d1bcc69c761 267 PANTHER PTHR13754 3 257 1.5E-69 T 22-04-2016 L21SP4_RS10215 dac726d04461f359b7f79d1bcc69c761 267 SMART SM00849 13 189 8.8E-7 T 22-04-2016 IPR001279 Metallo-beta-lactamase L21SP4_RS04480 cfe3f280eb576474ff6e1f0b3ebf77fa 706 Pfam PF00251 Glycosyl hydrolases family 32 N-terminal domain 272 467 8.1E-7 T 22-04-2016 IPR013148 Glycosyl hydrolase family 32, N-terminal L21SP4_RS04480 cfe3f280eb576474ff6e1f0b3ebf77fa 706 Gene3D G3DSA:2.60.120.200 11 187 1.4E-9 T 22-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP4_RS04480 cfe3f280eb576474ff6e1f0b3ebf77fa 706 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 96 184 1.6E-8 T 22-04-2016 L21SP4_RS04480 cfe3f280eb576474ff6e1f0b3ebf77fa 706 Gene3D G3DSA:2.60.120.560 552 705 1.7E-4 T 22-04-2016 IPR013189 Glycosyl hydrolase family 32, C-terminal L21SP4_RS04480 cfe3f280eb576474ff6e1f0b3ebf77fa 706 Gene3D G3DSA:2.115.10.20 344 443 5.8E-5 T 22-04-2016 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP4_RS04480 cfe3f280eb576474ff6e1f0b3ebf77fa 706 SUPERFAMILY SSF75005 233 482 6.75E-18 T 22-04-2016 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP4_RS04480 cfe3f280eb576474ff6e1f0b3ebf77fa 706 SUPERFAMILY SSF49899 552 704 3.39E-6 T 22-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP4_RS04480 cfe3f280eb576474ff6e1f0b3ebf77fa 706 SUPERFAMILY SSF49899 9 201 5.03E-14 T 22-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP4_RS04480 cfe3f280eb576474ff6e1f0b3ebf77fa 706 SMART SM00640 262 665 3.4E-5 T 22-04-2016 IPR001362 Glycoside hydrolase, family 32 GO:0004553|GO:0005975 L21SP4_RS11075 b839b1a647be9ec5efd48b91ca81667a 429 Pfam PF01565 FAD binding domain 21 129 7.4E-18 T 22-04-2016 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 L21SP4_RS11075 b839b1a647be9ec5efd48b91ca81667a 429 PANTHER PTHR13878 15 399 1.4E-48 T 22-04-2016 L21SP4_RS11075 b839b1a647be9ec5efd48b91ca81667a 429 Gene3D G3DSA:3.30.465.10 45 158 9.7E-27 T 22-04-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 L21SP4_RS11075 b839b1a647be9ec5efd48b91ca81667a 429 SUPERFAMILY SSF56176 21 160 1.45E-34 T 22-04-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 L21SP4_RS11075 b839b1a647be9ec5efd48b91ca81667a 429 PANTHER PTHR13878:SF52 15 399 1.4E-48 T 22-04-2016 L21SP4_RS10275 1bbb89e669a2de719b792178d744c136 335 PANTHER PTHR10457:SF4 5 316 2.3E-46 T 22-04-2016 IPR006205 Mevalonate kinase GO:0004496|GO:0005524|GO:0005737|GO:0008299 KEGG: 00900+2.7.1.36|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-922|UniPathway: UPA00057 L21SP4_RS10275 1bbb89e669a2de719b792178d744c136 335 Pfam PF00288 GHMP kinases N terminal domain 115 181 1.8E-15 T 22-04-2016 IPR006204 GHMP kinase N-terminal domain GO:0005524 L21SP4_RS10275 1bbb89e669a2de719b792178d744c136 335 Gene3D G3DSA:3.30.70.890 204 312 3.6E-15 T 22-04-2016 IPR013750 GHMP kinase, C-terminal domain L21SP4_RS10275 1bbb89e669a2de719b792178d744c136 335 PRINTS PR00959 Mevalonate kinase family signature 330 335 5.9E-18 T 22-04-2016 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 L21SP4_RS10275 1bbb89e669a2de719b792178d744c136 335 PRINTS PR00959 Mevalonate kinase family signature 119 141 5.9E-18 T 22-04-2016 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 L21SP4_RS10275 1bbb89e669a2de719b792178d744c136 335 PRINTS PR00959 Mevalonate kinase family signature 5 29 5.9E-18 T 22-04-2016 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 L21SP4_RS10275 1bbb89e669a2de719b792178d744c136 335 PRINTS PR00959 Mevalonate kinase family signature 162 181 5.9E-18 T 22-04-2016 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 L21SP4_RS10275 1bbb89e669a2de719b792178d744c136 335 SUPERFAMILY SSF55060 195 320 4.56E-14 T 22-04-2016 IPR013750 GHMP kinase, C-terminal domain L21SP4_RS10275 1bbb89e669a2de719b792178d744c136 335 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 121 132 - T 22-04-2016 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 L21SP4_RS10275 1bbb89e669a2de719b792178d744c136 335 PANTHER PTHR10457 5 316 2.3E-46 T 22-04-2016 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 L21SP4_RS10275 1bbb89e669a2de719b792178d744c136 335 SUPERFAMILY SSF54211 2 187 4.17E-32 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold L21SP4_RS10275 1bbb89e669a2de719b792178d744c136 335 Gene3D G3DSA:3.30.230.10 4 203 9.3E-40 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup L21SP4_RS01710 10bc6b835338e44d0ddf848bf4d2fe44 531 PANTHER PTHR32468:SF4 1 408 8.3E-92 T 22-04-2016 L21SP4_RS01710 10bc6b835338e44d0ddf848bf4d2fe44 531 Pfam PF00999 Sodium/hydrogen exchanger family 14 401 5.5E-56 T 22-04-2016 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 L21SP4_RS01710 10bc6b835338e44d0ddf848bf4d2fe44 531 PANTHER PTHR32468 1 408 8.3E-92 T 22-04-2016 L21SP4_RS11365 808de36c3792df357352b282d41ab13e 188 Gene3D G3DSA:3.30.70.940 11 113 2.6E-9 T 22-04-2016 IPR006645 NusG, N-terminal GO:0006355 L21SP4_RS11365 808de36c3792df357352b282d41ab13e 188 PANTHER PTHR30265:SF3 15 175 2.9E-14 T 22-04-2016 L21SP4_RS11365 808de36c3792df357352b282d41ab13e 188 SUPERFAMILY SSF82679 16 111 3.53E-18 T 22-04-2016 IPR006645 NusG, N-terminal GO:0006355 L21SP4_RS11365 808de36c3792df357352b282d41ab13e 188 Pfam PF02357 Transcription termination factor nusG 17 109 1.2E-12 T 22-04-2016 IPR006645 NusG, N-terminal GO:0006355 L21SP4_RS11365 808de36c3792df357352b282d41ab13e 188 PANTHER PTHR30265 15 175 2.9E-14 T 22-04-2016 L21SP4_RS11365 808de36c3792df357352b282d41ab13e 188 SUPERFAMILY SSF50104 126 175 6.02E-5 T 22-04-2016 IPR008991 Translation protein SH3-like domain L21SP4_RS11365 808de36c3792df357352b282d41ab13e 188 Gene3D G3DSA:2.30.30.30 127 175 2.4E-7 T 22-04-2016 IPR014722 Ribosomal protein L2 domain 2 L21SP4_RS02190 936c3b5978de3b4cc75befaf9e8da704 197 Gene3D G3DSA:1.10.10.10 124 188 1.1E-16 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS02190 936c3b5978de3b4cc75befaf9e8da704 197 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 19 186 2.6E-29 T 22-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP4_RS02190 936c3b5978de3b4cc75befaf9e8da704 197 Pfam PF04542 Sigma-70 region 2 24 89 2.1E-16 T 22-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP4_RS02190 936c3b5978de3b4cc75befaf9e8da704 197 Pfam PF08281 Sigma-70, region 4 130 182 2.5E-10 T 22-04-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP4_RS02190 936c3b5978de3b4cc75befaf9e8da704 197 SUPERFAMILY SSF88946 3 91 5.89E-25 T 22-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP4_RS02190 936c3b5978de3b4cc75befaf9e8da704 197 SUPERFAMILY SSF88659 101 188 7.2E-14 T 22-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP4_RS02190 936c3b5978de3b4cc75befaf9e8da704 197 Gene3D G3DSA:1.10.1740.10 3 101 2.6E-28 T 22-04-2016 L21SP4_RS02190 936c3b5978de3b4cc75befaf9e8da704 197 PANTHER PTHR30173 1 188 3.5E-42 T 22-04-2016 L21SP4_RS02180 fb859b5f6c35558bb4a3aa380f1ef25d 276 PIRSF PIRSF000161 7 276 3.4E-79 T 22-04-2016 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 L21SP4_RS02180 fb859b5f6c35558bb4a3aa380f1ef25d 276 Gene3D G3DSA:3.40.50.720 9 142 3.5E-12 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS02180 fb859b5f6c35558bb4a3aa380f1ef25d 276 SUPERFAMILY SSF51735 246 275 1.63E-40 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS02180 fb859b5f6c35558bb4a3aa380f1ef25d 276 SUPERFAMILY SSF51735 9 135 1.63E-40 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS02180 fb859b5f6c35558bb4a3aa380f1ef25d 276 SUPERFAMILY SSF55347 136 246 2.18E-31 T 22-04-2016 L21SP4_RS02180 fb859b5f6c35558bb4a3aa380f1ef25d 276 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 10 275 5.3E-79 T 22-04-2016 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 L21SP4_RS02180 fb859b5f6c35558bb4a3aa380f1ef25d 276 PANTHER PTHR20836 10 275 1.0E-80 T 22-04-2016 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 L21SP4_RS02180 fb859b5f6c35558bb4a3aa380f1ef25d 276 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 137 274 1.4E-43 T 22-04-2016 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 L21SP4_RS02180 fb859b5f6c35558bb4a3aa380f1ef25d 276 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 10 134 1.4E-27 T 22-04-2016 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 L21SP4_RS02180 fb859b5f6c35558bb4a3aa380f1ef25d 276 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 9 275 31.707 T 22-04-2016 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 L21SP4_RS02180 fb859b5f6c35558bb4a3aa380f1ef25d 276 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 160 177 - T 22-04-2016 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 L21SP4_RS02180 fb859b5f6c35558bb4a3aa380f1ef25d 276 Gene3D G3DSA:3.30.360.10 143 243 2.5E-34 T 22-04-2016 L21SP4_RS11345 bb622b082a3bf549097954ea41b98ae3 427 Gene3D G3DSA:3.40.50.720 7 195 3.9E-58 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS11345 bb622b082a3bf549097954ea41b98ae3 427 Gene3D G3DSA:3.40.50.720 232 423 1.5E-42 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS11345 bb622b082a3bf549097954ea41b98ae3 427 PANTHER PTHR11374 3 423 1.2E-239 T 22-04-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 L21SP4_RS11345 bb622b082a3bf549097954ea41b98ae3 427 SMART SM00984 317 420 2.6E-33 T 22-04-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 L21SP4_RS11345 bb622b082a3bf549097954ea41b98ae3 427 SUPERFAMILY SSF51735 7 191 8.3E-47 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS11345 bb622b082a3bf549097954ea41b98ae3 427 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 317 420 2.9E-20 T 22-04-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 L21SP4_RS11345 bb622b082a3bf549097954ea41b98ae3 427 SUPERFAMILY SSF48179 200 292 6.8E-25 T 22-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 L21SP4_RS11345 bb622b082a3bf549097954ea41b98ae3 427 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 7 180 1.6E-36 T 22-04-2016 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 L21SP4_RS11345 bb622b082a3bf549097954ea41b98ae3 427 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 202 290 7.2E-23 T 22-04-2016 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 L21SP4_RS11345 bb622b082a3bf549097954ea41b98ae3 427 SUPERFAMILY SSF52413 302 421 2.88E-27 T 22-04-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 L21SP4_RS11345 bb622b082a3bf549097954ea41b98ae3 427 PANTHER PTHR11374:SF25 3 423 1.2E-239 T 22-04-2016 L21SP4_RS11345 bb622b082a3bf549097954ea41b98ae3 427 PIRSF PIRSF500136 1 427 2.6E-150 T 22-04-2016 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 L21SP4_RS11345 bb622b082a3bf549097954ea41b98ae3 427 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 7 415 1.7E-120 T 22-04-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 L21SP4_RS11345 bb622b082a3bf549097954ea41b98ae3 427 PIRSF PIRSF000124 6 425 2.8E-55 T 22-04-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 L21SP4_RS00110 e4ddb16b91184a622ed5b07b673a4698 139 SUPERFAMILY SSF49764 28 137 1.31E-31 T 22-04-2016 IPR008978 HSP20-like chaperone L21SP4_RS00110 e4ddb16b91184a622ed5b07b673a4698 139 Gene3D G3DSA:2.60.40.790 20 137 6.4E-31 T 22-04-2016 IPR008978 HSP20-like chaperone L21SP4_RS00110 e4ddb16b91184a622ed5b07b673a4698 139 PANTHER PTHR11527:SF118 5 139 1.2E-24 T 22-04-2016 L21SP4_RS00110 e4ddb16b91184a622ed5b07b673a4698 139 PANTHER PTHR11527 5 139 1.2E-24 T 22-04-2016 IPR031107 Small heat shock protein HSP20 L21SP4_RS00110 e4ddb16b91184a622ed5b07b673a4698 139 Pfam PF00011 Hsp20/alpha crystallin family 38 136 7.6E-21 T 22-04-2016 IPR002068 Alpha crystallin/Hsp20 domain L21SP4_RS04215 5496c1215c631235d2b62585c13911e6 1050 Pfam PF08264 Anticodon-binding domain of tRNA 679 826 6.8E-29 T 22-04-2016 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 Reactome: REACT_71 L21SP4_RS04215 5496c1215c631235d2b62585c13911e6 1050 PANTHER PTHR11946:SF73 1 245 0.0 T 22-04-2016 L21SP4_RS04215 5496c1215c631235d2b62585c13911e6 1050 PANTHER PTHR11946:SF73 269 932 0.0 T 22-04-2016 L21SP4_RS04215 5496c1215c631235d2b62585c13911e6 1050 Gene3D G3DSA:3.40.50.620 397 627 8.8E-146 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP4_RS04215 5496c1215c631235d2b62585c13911e6 1050 Gene3D G3DSA:3.40.50.620 6 194 8.8E-146 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP4_RS04215 5496c1215c631235d2b62585c13911e6 1050 Gene3D G3DSA:3.90.740.10 225 396 4.1E-55 T 22-04-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Reactome: REACT_71 L21SP4_RS04215 5496c1215c631235d2b62585c13911e6 1050 PANTHER PTHR11946 1 245 0.0 T 22-04-2016 L21SP4_RS04215 5496c1215c631235d2b62585c13911e6 1050 PANTHER PTHR11946 269 932 0.0 T 22-04-2016 L21SP4_RS04215 5496c1215c631235d2b62585c13911e6 1050 Hamap MF_02003 Isoleucine--tRNA ligase [ileS]. 3 1042 13.664 T 22-04-2016 IPR023586 Isoleucine-tRNA ligase, type 2 GO:0004822 KEGG: 00970+6.1.1.5 L21SP4_RS04215 5496c1215c631235d2b62585c13911e6 1050 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 18 631 5.7E-203 T 22-04-2016 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 L21SP4_RS04215 5496c1215c631235d2b62585c13911e6 1050 SUPERFAMILY SSF47323 649 887 2.99E-54 T 22-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 L21SP4_RS04215 5496c1215c631235d2b62585c13911e6 1050 SUPERFAMILY SSF52374 6 198 4.46E-126 T 22-04-2016 L21SP4_RS04215 5496c1215c631235d2b62585c13911e6 1050 SUPERFAMILY SSF52374 393 642 4.46E-126 T 22-04-2016 L21SP4_RS04215 5496c1215c631235d2b62585c13911e6 1050 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 224 247 1.7E-29 T 22-04-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 L21SP4_RS04215 5496c1215c631235d2b62585c13911e6 1050 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 552 561 1.7E-29 T 22-04-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 L21SP4_RS04215 5496c1215c631235d2b62585c13911e6 1050 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 41 52 1.7E-29 T 22-04-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 L21SP4_RS04215 5496c1215c631235d2b62585c13911e6 1050 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 512 525 1.7E-29 T 22-04-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 L21SP4_RS04215 5496c1215c631235d2b62585c13911e6 1050 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 391 406 1.7E-29 T 22-04-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 L21SP4_RS04215 5496c1215c631235d2b62585c13911e6 1050 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 6 836 2.4E-288 T 22-04-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 L21SP4_RS04215 5496c1215c631235d2b62585c13911e6 1050 Gene3D G3DSA:1.10.730.10 633 818 1.4E-53 T 22-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 L21SP4_RS04215 5496c1215c631235d2b62585c13911e6 1050 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 48 59 - T 22-04-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 L21SP4_RS04215 5496c1215c631235d2b62585c13911e6 1050 SUPERFAMILY SSF50677 200 393 3.87E-44 T 22-04-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Reactome: REACT_71 L21SP4_RS10230 f87eb9f3a8dc6cfc370a1f6f6376e7ea 498 PANTHER PTHR11895 1 485 6.5E-230 T 22-04-2016 IPR000120 Amidase GO:0016884 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 L21SP4_RS10230 f87eb9f3a8dc6cfc370a1f6f6376e7ea 498 Gene3D G3DSA:3.90.1300.10 2 486 8.9E-183 T 22-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 L21SP4_RS10230 f87eb9f3a8dc6cfc370a1f6f6376e7ea 498 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 12 479 91.181 T 22-04-2016 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 L21SP4_RS10230 f87eb9f3a8dc6cfc370a1f6f6376e7ea 498 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 14 479 2.1E-178 T 22-04-2016 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 L21SP4_RS10230 f87eb9f3a8dc6cfc370a1f6f6376e7ea 498 PANTHER PTHR11895:SF75 1 485 6.5E-230 T 22-04-2016 L21SP4_RS10230 f87eb9f3a8dc6cfc370a1f6f6376e7ea 498 Pfam PF01425 Amidase 26 468 1.3E-155 T 22-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 L21SP4_RS10230 f87eb9f3a8dc6cfc370a1f6f6376e7ea 498 ProSitePatterns PS00571 Amidases signature. 152 183 - T 22-04-2016 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 L21SP4_RS10230 f87eb9f3a8dc6cfc370a1f6f6376e7ea 498 SUPERFAMILY SSF75304 3 486 2.22E-165 T 22-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 L21SP4_RS10815 6a1eb654d1cb79f0995bc45a417c25b8 301 Gene3D G3DSA:3.40.50.1820 19 299 4.1E-44 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold L21SP4_RS10815 6a1eb654d1cb79f0995bc45a417c25b8 301 PANTHER PTHR10655:SF33 18 196 1.4E-39 T 22-04-2016 L21SP4_RS10815 6a1eb654d1cb79f0995bc45a417c25b8 301 Pfam PF10503 Esterase PHB depolymerase 32 166 1.4E-10 T 22-04-2016 IPR010126 Esterase, PHB depolymerase GO:0005576 L21SP4_RS10815 6a1eb654d1cb79f0995bc45a417c25b8 301 SUPERFAMILY SSF53474 245 281 1.11E-30 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold L21SP4_RS10815 6a1eb654d1cb79f0995bc45a417c25b8 301 SUPERFAMILY SSF53474 20 195 1.11E-30 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold L21SP4_RS10815 6a1eb654d1cb79f0995bc45a417c25b8 301 PANTHER PTHR10655 18 196 1.4E-39 T 22-04-2016 L21SP4_RS01505 0129e7705d11dd970ce8151638a0ff53 249 PANTHER PTHR24220 7 235 7.2E-73 T 22-04-2016 L21SP4_RS01505 0129e7705d11dd970ce8151638a0ff53 249 SMART SM00382 30 219 6.1E-9 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS01505 0129e7705d11dd970ce8151638a0ff53 249 PANTHER PTHR24220:SF504 7 235 7.2E-73 T 22-04-2016 L21SP4_RS01505 0129e7705d11dd970ce8151638a0ff53 249 Pfam PF00005 ABC transporter 21 165 1.4E-23 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 L21SP4_RS01505 0129e7705d11dd970ce8151638a0ff53 249 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 L21SP4_RS01505 0129e7705d11dd970ce8151638a0ff53 249 SUPERFAMILY SSF52540 4 227 1.62E-49 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS01505 0129e7705d11dd970ce8151638a0ff53 249 Gene3D G3DSA:3.40.50.300 3 223 7.9E-54 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS07375 6daa4d6b67fd14e62febad04fff7e7ba 376 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 265 288 2.9E-4 T 22-04-2016 IPR013424 PEP-CTERM protein-sorting domain L21SP4_RS07375 6daa4d6b67fd14e62febad04fff7e7ba 376 TIGRFAM TIGR02913 HAF_rpt: probable extracellular repeat, HAF family 10 46 1.6E-11 T 22-04-2016 IPR014262 Extracellular HAF L21SP4_RS07375 6daa4d6b67fd14e62febad04fff7e7ba 376 TIGRFAM TIGR02913 HAF_rpt: probable extracellular repeat, HAF family 51 89 3.5E-8 T 22-04-2016 IPR014262 Extracellular HAF L21SP4_RS07375 6daa4d6b67fd14e62febad04fff7e7ba 376 TIGRFAM TIGR03382 GC_trans_RRR: Myxococcales GC_trans_RRR domain 268 288 0.0035 T 22-04-2016 IPR017756 Transmembrane Gly-Cys-Arg, conserved site L21SP4_RS11010 e52f28541fd976aef9cd53e1bafd7888 440 Gene3D G3DSA:3.20.20.210 1 332 2.9E-57 T 22-04-2016 L21SP4_RS11010 e52f28541fd976aef9cd53e1bafd7888 440 SUPERFAMILY SSF52833 373 436 7.75E-6 T 22-04-2016 IPR012336 Thioredoxin-like fold L21SP4_RS11010 e52f28541fd976aef9cd53e1bafd7888 440 Gene3D G3DSA:3.40.30.10 373 438 9.8E-7 T 22-04-2016 IPR012336 Thioredoxin-like fold L21SP4_RS11010 e52f28541fd976aef9cd53e1bafd7888 440 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 4 332 7.5E-56 T 22-04-2016 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 L21SP4_RS11010 e52f28541fd976aef9cd53e1bafd7888 440 PANTHER PTHR21091 124 376 1.0E-17 T 22-04-2016 L21SP4_RS11010 e52f28541fd976aef9cd53e1bafd7888 440 SUPERFAMILY SSF51726 4 332 6.67E-57 T 22-04-2016 L21SP4_RS11010 e52f28541fd976aef9cd53e1bafd7888 440 PANTHER PTHR21091:SF117 124 376 1.0E-17 T 22-04-2016 L21SP4_RS11630 4778c85d58ef5b5ffcffeecd742d5a1c 84 Pfam PF12833 Helix-turn-helix domain 3 79 2.8E-19 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP4_RS11630 4778c85d58ef5b5ffcffeecd742d5a1c 84 PANTHER PTHR11019 4 78 5.4E-18 T 22-04-2016 L21SP4_RS11630 4778c85d58ef5b5ffcffeecd742d5a1c 84 PANTHER PTHR11019:SF141 4 78 5.4E-18 T 22-04-2016 L21SP4_RS11630 4778c85d58ef5b5ffcffeecd742d5a1c 84 SMART SM00342 1 78 2.0E-12 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP4_RS11630 4778c85d58ef5b5ffcffeecd742d5a1c 84 Gene3D G3DSA:1.10.10.60 34 81 2.9E-14 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS11630 4778c85d58ef5b5ffcffeecd742d5a1c 84 Gene3D G3DSA:1.10.10.60 7 33 3.1E-6 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS11630 4778c85d58ef5b5ffcffeecd742d5a1c 84 SUPERFAMILY SSF46689 32 81 3.36E-12 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS02650 bcfcefc6b0345fe5e4c1c4f3efd5e31c 170 PANTHER PTHR23026:SF103 1 167 3.3E-41 T 22-04-2016 L21SP4_RS02650 bcfcefc6b0345fe5e4c1c4f3efd5e31c 170 Gene3D G3DSA:3.40.109.10 1 168 3.1E-49 T 22-04-2016 IPR000415 Nitroreductase-like GO:0016491 L21SP4_RS02650 bcfcefc6b0345fe5e4c1c4f3efd5e31c 170 Pfam PF00881 Nitroreductase family 8 72 7.9E-16 T 22-04-2016 IPR029479 Nitroreductase L21SP4_RS02650 bcfcefc6b0345fe5e4c1c4f3efd5e31c 170 PANTHER PTHR23026 1 167 3.3E-41 T 22-04-2016 L21SP4_RS02650 bcfcefc6b0345fe5e4c1c4f3efd5e31c 170 SUPERFAMILY SSF55469 1 167 5.1E-47 T 22-04-2016 IPR000415 Nitroreductase-like GO:0016491 L21SP4_RS04360 f24ab6766168a9a5dcce37b6392865e5 366 Gene3D G3DSA:1.10.150.20 2 47 4.6E-9 T 22-04-2016 L21SP4_RS04360 f24ab6766168a9a5dcce37b6392865e5 366 Gene3D G3DSA:3.40.50.450 102 270 1.1E-12 T 22-04-2016 L21SP4_RS04360 f24ab6766168a9a5dcce37b6392865e5 366 SUPERFAMILY SSF47781 3 47 3.71E-8 T 22-04-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 L21SP4_RS04360 f24ab6766168a9a5dcce37b6392865e5 366 SUPERFAMILY SSF102405 70 276 1.98E-42 T 22-04-2016 L21SP4_RS04360 f24ab6766168a9a5dcce37b6392865e5 366 Pfam PF02481 DNA recombination-mediator protein A 62 267 1.3E-82 T 22-04-2016 IPR003488 DNA recombination-mediator protein A GO:0009294 L21SP4_RS04360 f24ab6766168a9a5dcce37b6392865e5 366 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 61 275 5.0E-78 T 22-04-2016 IPR003488 DNA recombination-mediator protein A GO:0009294 L21SP4_RS04360 f24ab6766168a9a5dcce37b6392865e5 366 PANTHER PTHR32039:SF8 9 352 9.8E-103 T 22-04-2016 L21SP4_RS04360 f24ab6766168a9a5dcce37b6392865e5 366 Pfam PF14520 Helix-hairpin-helix domain 2 47 6.8E-6 T 22-04-2016 L21SP4_RS04360 f24ab6766168a9a5dcce37b6392865e5 366 PANTHER PTHR32039 9 352 9.8E-103 T 22-04-2016 L21SP4_RS03970 40cc8c16430914a090c4deba2004282f 454 SUPERFAMILY SSF51246 332 447 6.8E-44 T 22-04-2016 IPR011054 Rudiment single hybrid motif L21SP4_RS03970 40cc8c16430914a090c4deba2004282f 454 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 287 294 - T 22-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 L21SP4_RS03970 40cc8c16430914a090c4deba2004282f 454 Gene3D G3DSA:3.40.50.20 1 129 9.3E-52 T 22-04-2016 IPR016185 Pre-ATP-grasp domain L21SP4_RS03970 40cc8c16430914a090c4deba2004282f 454 Gene3D G3DSA:3.30.470.20 203 447 5.2E-102 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 L21SP4_RS03970 40cc8c16430914a090c4deba2004282f 454 Gene3D G3DSA:3.30.1490.20 130 202 1.4E-26 T 22-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 L21SP4_RS03970 40cc8c16430914a090c4deba2004282f 454 SUPERFAMILY SSF56059 83 353 3.89E-68 T 22-04-2016 L21SP4_RS03970 40cc8c16430914a090c4deba2004282f 454 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 323 1.1E-79 T 22-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 L21SP4_RS03970 40cc8c16430914a090c4deba2004282f 454 SMART SM00878 337 443 1.0E-60 T 22-04-2016 IPR005482 Biotin carboxylase, C-terminal L21SP4_RS03970 40cc8c16430914a090c4deba2004282f 454 SUPERFAMILY SSF52440 1 113 4.24E-48 T 22-04-2016 IPR016185 Pre-ATP-grasp domain L21SP4_RS03970 40cc8c16430914a090c4deba2004282f 454 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 446 1.2E-218 T 22-04-2016 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 L21SP4_RS03970 40cc8c16430914a090c4deba2004282f 454 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 109 8.9E-45 T 22-04-2016 IPR005481 Biotin carboxylase-like, N-terminal domain L21SP4_RS03970 40cc8c16430914a090c4deba2004282f 454 PANTHER PTHR18866 1 454 2.0E-291 T 22-04-2016 L21SP4_RS03970 40cc8c16430914a090c4deba2004282f 454 Pfam PF02785 Biotin carboxylase C-terminal domain 337 444 1.7E-40 T 22-04-2016 IPR005482 Biotin carboxylase, C-terminal L21SP4_RS02805 c2269b4bbb3c2208fce6b238eaa51769 153 PANTHER PTHR11717 6 146 2.4E-42 T 22-04-2016 L21SP4_RS02805 c2269b4bbb3c2208fce6b238eaa51769 153 SUPERFAMILY SSF52788 8 142 2.09E-42 T 22-04-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily L21SP4_RS02805 c2269b4bbb3c2208fce6b238eaa51769 153 Gene3D G3DSA:3.40.50.270 7 142 5.5E-46 T 22-04-2016 L21SP4_RS02805 c2269b4bbb3c2208fce6b238eaa51769 153 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 11 141 6.6E-20 T 22-04-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily L21SP4_RS02805 c2269b4bbb3c2208fce6b238eaa51769 153 SMART SM00226 9 145 1.4E-40 T 22-04-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily L21SP4_RS02805 c2269b4bbb3c2208fce6b238eaa51769 153 PANTHER PTHR11717:SF18 6 146 2.4E-42 T 22-04-2016 L21SP4_RS01995 b245ef5bcd9fd5a0c13aed34c635c644 880 Pfam PF01229 Glycosyl hydrolases family 39 307 487 4.4E-11 T 22-04-2016 IPR000514 Glycoside hydrolase, family 39 GO:0004553|GO:0005975 L21SP4_RS01995 b245ef5bcd9fd5a0c13aed34c635c644 880 Gene3D G3DSA:2.60.40.10 68 109 5.6E-5 T 22-04-2016 IPR013783 Immunoglobulin-like fold L21SP4_RS01995 b245ef5bcd9fd5a0c13aed34c635c644 880 Gene3D G3DSA:3.20.20.80 272 560 2.2E-20 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP4_RS01995 b245ef5bcd9fd5a0c13aed34c635c644 880 SUPERFAMILY SSF51445 301 561 1.93E-14 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily L21SP4_RS01995 b245ef5bcd9fd5a0c13aed34c635c644 880 SUPERFAMILY SSF49265 62 108 3.01E-7 T 22-04-2016 IPR003961 Fibronectin type III GO:0005515 L21SP4_RS09925 79668fa93dfc8f1934620cbfd987bc3c 395 PANTHER PTHR11751:SF404 18 388 4.1E-154 T 22-04-2016 L21SP4_RS09925 79668fa93dfc8f1934620cbfd987bc3c 395 SUPERFAMILY SSF53383 14 389 3.23E-117 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase L21SP4_RS09925 79668fa93dfc8f1934620cbfd987bc3c 395 PANTHER PTHR11751 18 388 4.1E-154 T 22-04-2016 L21SP4_RS09925 79668fa93dfc8f1934620cbfd987bc3c 395 Pfam PF00155 Aminotransferase class I and II 35 384 7.9E-67 T 22-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 L21SP4_RS09925 79668fa93dfc8f1934620cbfd987bc3c 395 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 237 250 - T 22-04-2016 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 Reactome: REACT_13 L21SP4_RS09925 79668fa93dfc8f1934620cbfd987bc3c 395 Gene3D G3DSA:3.90.1150.10 275 390 3.0E-40 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 L21SP4_RS09925 79668fa93dfc8f1934620cbfd987bc3c 395 Gene3D G3DSA:3.40.640.10 49 274 1.1E-72 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 L21SP4_RS09680 f37f5870d37d9291cec92f95db0d816e 153 SUPERFAMILY SSF53335 16 150 5.54E-19 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS09680 f37f5870d37d9291cec92f95db0d816e 153 Pfam PF02384 N-6 DNA Methylase 16 101 2.4E-8 T 22-04-2016 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 L21SP4_RS05055 582f369a7cbf5c91149048cc8ceff431 249 Gene3D G3DSA:3.30.160.20 162 227 1.8E-21 T 22-04-2016 IPR014720 Double-stranded RNA-binding domain L21SP4_RS05055 582f369a7cbf5c91149048cc8ceff431 249 Gene3D G3DSA:1.10.1520.10 9 147 4.5E-44 T 22-04-2016 IPR000999 Ribonuclease III domain GO:0003723|GO:0004525|GO:0006396 L21SP4_RS05055 582f369a7cbf5c91149048cc8ceff431 249 SUPERFAMILY SSF69065 9 147 2.27E-44 T 22-04-2016 IPR000999 Ribonuclease III domain GO:0003723|GO:0004525|GO:0006396 L21SP4_RS05055 582f369a7cbf5c91149048cc8ceff431 249 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 10 227 7.9E-68 T 22-04-2016 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 L21SP4_RS05055 582f369a7cbf5c91149048cc8ceff431 249 Pfam PF00035 Double-stranded RNA binding motif 163 227 1.3E-14 T 22-04-2016 IPR014720 Double-stranded RNA-binding domain L21SP4_RS05055 582f369a7cbf5c91149048cc8ceff431 249 Pfam PF14622 Ribonuclease-III-like 20 146 6.6E-34 T 22-04-2016 IPR000999 Ribonuclease III domain GO:0003723|GO:0004525|GO:0006396 L21SP4_RS05055 582f369a7cbf5c91149048cc8ceff431 249 PANTHER PTHR11207 10 229 9.1E-73 T 22-04-2016 L21SP4_RS05055 582f369a7cbf5c91149048cc8ceff431 249 Hamap MF_00104 Ribonuclease 3 [rnc]. 10 226 29.148 T 22-04-2016 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 L21SP4_RS05055 582f369a7cbf5c91149048cc8ceff431 249 SMART SM00535 22 156 3.0E-41 T 22-04-2016 IPR000999 Ribonuclease III domain GO:0003723|GO:0004525|GO:0006396 L21SP4_RS05055 582f369a7cbf5c91149048cc8ceff431 249 SMART SM00358 163 230 1.3E-18 T 22-04-2016 IPR014720 Double-stranded RNA-binding domain L21SP4_RS05055 582f369a7cbf5c91149048cc8ceff431 249 ProSitePatterns PS00517 Ribonuclease III family signature. 45 53 - T 22-04-2016 IPR000999 Ribonuclease III domain GO:0003723|GO:0004525|GO:0006396 L21SP4_RS05055 582f369a7cbf5c91149048cc8ceff431 249 SUPERFAMILY SSF54768 117 229 5.81E-20 T 22-04-2016 L21SP4_RS07710 818c3b6d4ce871ce7b43392531d95845 299 SUPERFAMILY SSF160240 211 284 2.22E-5 T 22-04-2016 L21SP4_RS07710 818c3b6d4ce871ce7b43392531d95845 299 PANTHER PTHR11562 2 295 7.2E-78 T 22-04-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 L21SP4_RS07710 818c3b6d4ce871ce7b43392531d95845 299 SUPERFAMILY SSF161111 11 206 5.75E-50 T 22-04-2016 L21SP4_RS07710 818c3b6d4ce871ce7b43392531d95845 299 Pfam PF01545 Cation efflux family 17 205 1.5E-40 T 22-04-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 L21SP4_RS07710 818c3b6d4ce871ce7b43392531d95845 299 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 13 286 5.9E-75 T 22-04-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 L21SP4_RS07710 818c3b6d4ce871ce7b43392531d95845 299 Gene3D G3DSA:1.20.1510.10 12 205 2.2E-53 T 22-04-2016 IPR027469 Cation efflux protein transmembrane domain L21SP4_RS11170 bcd5efd7dcfb026344856d37ff492cb5 261 PANTHER PTHR34136 4 251 5.2E-59 T 22-04-2016 L21SP4_RS11170 bcd5efd7dcfb026344856d37ff492cb5 261 TIGRFAM TIGR00696 wecG_tagA_cpsF: glycosyltransferase, WecB/TagA/CpsF family 64 239 1.0E-40 T 22-04-2016 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|UniPathway: UPA00566 L21SP4_RS11170 bcd5efd7dcfb026344856d37ff492cb5 261 Pfam PF03808 Glycosyl transferase WecB/TagA/CpsF family 70 237 1.9E-47 T 22-04-2016 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|UniPathway: UPA00566 L21SP4_RS08715 b472c43996873ba1bfcf2dfc797097b2 394 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 7 352 4.7E-90 T 22-04-2016 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525|UniPathway: UPA00275|UniPathway: UPA00275 L21SP4_RS08715 b472c43996873ba1bfcf2dfc797097b2 394 Gene3D G3DSA:3.40.430.10 132 354 1.2E-70 T 22-04-2016 IPR024072 Dihydrofolate reductase-like domain L21SP4_RS08715 b472c43996873ba1bfcf2dfc797097b2 394 PANTHER PTHR11079 3 223 1.8E-48 T 22-04-2016 L21SP4_RS08715 b472c43996873ba1bfcf2dfc797097b2 394 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 150 355 3.9E-47 T 22-04-2016 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 L21SP4_RS08715 b472c43996873ba1bfcf2dfc797097b2 394 Pfam PF01872 RibD C-terminal domain 151 352 2.3E-41 T 22-04-2016 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 L21SP4_RS08715 b472c43996873ba1bfcf2dfc797097b2 394 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 3 104 1.4E-18 T 22-04-2016 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 L21SP4_RS08715 b472c43996873ba1bfcf2dfc797097b2 394 SUPERFAMILY SSF53927 4 146 7.15E-42 T 22-04-2016 IPR016193 Cytidine deaminase-like GO:0003824 L21SP4_RS08715 b472c43996873ba1bfcf2dfc797097b2 394 PIRSF PIRSF006769 1 359 3.3E-108 T 22-04-2016 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525|UniPathway: UPA00275|UniPathway: UPA00275 L21SP4_RS08715 b472c43996873ba1bfcf2dfc797097b2 394 SUPERFAMILY SSF53597 149 353 6.04E-55 T 22-04-2016 IPR024072 Dihydrofolate reductase-like domain L21SP4_RS08715 b472c43996873ba1bfcf2dfc797097b2 394 Gene3D G3DSA:3.40.140.10 2 131 5.5E-30 T 22-04-2016 L21SP4_RS08715 b472c43996873ba1bfcf2dfc797097b2 394 PANTHER PTHR11079:SF10 3 223 1.8E-48 T 22-04-2016 L21SP4_RS08120 ceef3c891062e048d81d83bd8c856ea1 476 Pfam PF01957 NfeD-like C-terminal, partner-binding 334 474 8.6E-24 T 22-04-2016 IPR002810 NfeD-like, C-terminal domain L21SP4_RS08120 ceef3c891062e048d81d83bd8c856ea1 476 PANTHER PTHR33507 1 137 3.0E-122 T 22-04-2016 L21SP4_RS08120 ceef3c891062e048d81d83bd8c856ea1 476 PANTHER PTHR33507 175 475 3.0E-122 T 22-04-2016 L21SP4_RS08120 ceef3c891062e048d81d83bd8c856ea1 476 Gene3D G3DSA:3.90.226.10 209 238 4.0E-16 T 22-04-2016 IPR029045 ClpP/crotonase-like domain L21SP4_RS08120 ceef3c891062e048d81d83bd8c856ea1 476 Gene3D G3DSA:3.90.226.10 33 129 4.0E-16 T 22-04-2016 IPR029045 ClpP/crotonase-like domain L21SP4_RS08120 ceef3c891062e048d81d83bd8c856ea1 476 SUPERFAMILY SSF141322 437 474 1.29E-7 T 22-04-2016 L21SP4_RS08120 ceef3c891062e048d81d83bd8c856ea1 476 SUPERFAMILY SSF52096 13 133 7.87E-24 T 22-04-2016 IPR029045 ClpP/crotonase-like domain L21SP4_RS08120 ceef3c891062e048d81d83bd8c856ea1 476 SUPERFAMILY SSF52096 175 234 7.87E-24 T 22-04-2016 IPR029045 ClpP/crotonase-like domain L21SP4_RS08120 ceef3c891062e048d81d83bd8c856ea1 476 PANTHER PTHR33507:SF1 1 137 3.0E-122 T 22-04-2016 L21SP4_RS08120 ceef3c891062e048d81d83bd8c856ea1 476 PANTHER PTHR33507:SF1 175 475 3.0E-122 T 22-04-2016 L21SP4_RS08120 ceef3c891062e048d81d83bd8c856ea1 476 Gene3D G3DSA:2.40.50.140 421 474 3.8E-9 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold L21SP4_RS04030 ceffeaf8e79b4441819182052219f050 601 Pfam PF00682 HMGL-like 5 281 1.9E-20 T 22-04-2016 IPR000891 Pyruvate carboxyltransferase GO:0003824 L21SP4_RS04030 ceffeaf8e79b4441819182052219f050 601 Pfam PF02436 Conserved carboxylase domain 306 493 2.5E-39 T 22-04-2016 IPR003379 Carboxylase, conserved domain L21SP4_RS04030 ceffeaf8e79b4441819182052219f050 601 Pfam PF00364 Biotin-requiring enzyme 535 598 1.6E-17 T 22-04-2016 IPR000089 Biotin/lipoyl attachment L21SP4_RS04030 ceffeaf8e79b4441819182052219f050 601 Gene3D G3DSA:3.20.20.70 3 290 1.8E-73 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP4_RS04030 ceffeaf8e79b4441819182052219f050 601 SUPERFAMILY SSF51569 3 293 1.68E-60 T 22-04-2016 L21SP4_RS04030 ceffeaf8e79b4441819182052219f050 601 PANTHER PTHR18866:SF109 4 601 5.7E-73 T 22-04-2016 L21SP4_RS04030 ceffeaf8e79b4441819182052219f050 601 Gene3D G3DSA:2.40.50.100 530 600 7.7E-25 T 22-04-2016 L21SP4_RS04030 ceffeaf8e79b4441819182052219f050 601 PANTHER PTHR18866 4 601 5.7E-73 T 22-04-2016 L21SP4_RS04030 ceffeaf8e79b4441819182052219f050 601 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 557 574 - T 22-04-2016 IPR001882 Biotin-binding site L21SP4_RS04030 ceffeaf8e79b4441819182052219f050 601 SUPERFAMILY SSF89000 307 465 3.22E-36 T 22-04-2016 L21SP4_RS04030 ceffeaf8e79b4441819182052219f050 601 SUPERFAMILY SSF51230 525 600 8.11E-22 T 22-04-2016 IPR011053 Single hybrid motif L21SP4_RS08885 43c53f844ca027314374eee011e4793c 707 SUPERFAMILY SSF140356 5 108 1.44E-37 T 22-04-2016 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 L21SP4_RS08885 43c53f844ca027314374eee011e4793c 707 Gene3D G3DSA:3.30.1840.10 110 298 5.7E-52 T 22-04-2016 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 L21SP4_RS08885 43c53f844ca027314374eee011e4793c 707 SUPERFAMILY SSF56024 500 680 2.92E-69 T 22-04-2016 L21SP4_RS08885 43c53f844ca027314374eee011e4793c 707 PANTHER PTHR30218:SF0 8 701 0.0 T 22-04-2016 L21SP4_RS08885 43c53f844ca027314374eee011e4793c 707 SUPERFAMILY SSF143724 111 309 1.57E-47 T 22-04-2016 L21SP4_RS08885 43c53f844ca027314374eee011e4793c 707 SUPERFAMILY SSF56024 314 495 8.52E-53 T 22-04-2016 L21SP4_RS08885 43c53f844ca027314374eee011e4793c 707 Gene3D G3DSA:3.30.870.10 499 679 1.8E-71 T 22-04-2016 L21SP4_RS08885 43c53f844ca027314374eee011e4793c 707 Pfam PF13089 Polyphosphate kinase N-terminal domain 8 112 1.5E-38 T 22-04-2016 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 L21SP4_RS08885 43c53f844ca027314374eee011e4793c 707 Pfam PF13090 Polyphosphate kinase C-terminal domain 329 675 7.3E-150 T 22-04-2016 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 L21SP4_RS08885 43c53f844ca027314374eee011e4793c 707 Gene3D G3DSA:3.30.870.10 314 498 8.9E-70 T 22-04-2016 L21SP4_RS08885 43c53f844ca027314374eee011e4793c 707 PIRSF PIRSF015589 1 693 1.6E-268 T 22-04-2016 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 L21SP4_RS08885 43c53f844ca027314374eee011e4793c 707 Hamap MF_00347 Polyphosphate kinase [ppk]. 5 680 31.247 T 22-04-2016 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 L21SP4_RS08885 43c53f844ca027314374eee011e4793c 707 PANTHER PTHR30218 8 701 0.0 T 22-04-2016 L21SP4_RS08885 43c53f844ca027314374eee011e4793c 707 Pfam PF02503 Polyphosphate kinase middle domain 124 321 6.0E-55 T 22-04-2016 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 L21SP4_RS08885 43c53f844ca027314374eee011e4793c 707 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 8 675 2.6E-251 T 22-04-2016 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 L21SP4_RS10045 eff984156e4b09c9191c6a1dfe87820a 127 Gene3D G3DSA:3.40.50.1010 1 123 1.5E-17 T 22-04-2016 IPR029060 PIN domain-like L21SP4_RS10045 eff984156e4b09c9191c6a1dfe87820a 127 PANTHER PTHR33653 1 124 5.4E-18 T 22-04-2016 L21SP4_RS10045 eff984156e4b09c9191c6a1dfe87820a 127 PANTHER PTHR33653:SF2 1 124 5.4E-18 T 22-04-2016 L21SP4_RS10045 eff984156e4b09c9191c6a1dfe87820a 127 Pfam PF01850 PIN domain 4 119 1.4E-9 T 22-04-2016 IPR002716 PIN domain L21SP4_RS10045 eff984156e4b09c9191c6a1dfe87820a 127 SUPERFAMILY SSF88723 1 124 2.13E-21 T 22-04-2016 IPR029060 PIN domain-like L21SP4_RS06535 85a6a1fc5b2a89913c236bd6e8021050 484 PANTHER PTHR11328:SF24 17 477 6.3E-42 T 22-04-2016 L21SP4_RS06535 85a6a1fc5b2a89913c236bd6e8021050 484 PANTHER PTHR11328 17 477 6.3E-42 T 22-04-2016 L21SP4_RS06535 85a6a1fc5b2a89913c236bd6e8021050 484 Gene3D G3DSA:1.20.1250.20 23 219 1.1E-11 T 22-04-2016 L21SP4_RS06535 85a6a1fc5b2a89913c236bd6e8021050 484 SUPERFAMILY SSF103473 18 472 2.7E-23 T 22-04-2016 IPR020846 Major facilitator superfamily domain L21SP4_RS06535 85a6a1fc5b2a89913c236bd6e8021050 484 Pfam PF13347 MFS/sugar transport protein 17 472 8.9E-70 T 22-04-2016 L21SP4_RS10205 900e50521a839516d4afcd21ca727372 371 SUPERFAMILY SSF47413 1 49 2.7E-9 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 L21SP4_RS10205 900e50521a839516d4afcd21ca727372 371 Pfam PF06114 Domain of unknown function (DUF955) 161 297 5.8E-13 T 22-04-2016 IPR010359 HTH domain, IrrE-type L21SP4_RS10205 900e50521a839516d4afcd21ca727372 371 Gene3D G3DSA:1.10.260.40 1 48 1.0E-9 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 L21SP4_RS10205 900e50521a839516d4afcd21ca727372 371 Pfam PF01381 Helix-turn-helix 1 45 1.4E-6 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 L21SP4_RS11885 53f863283305f9194acc55df15a0d29e 338 Gene3D G3DSA:1.10.8.60 185 256 2.7E-31 T 22-04-2016 L21SP4_RS11885 53f863283305f9194acc55df15a0d29e 338 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 254 327 1.5E-29 T 22-04-2016 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 L21SP4_RS11885 53f863283305f9194acc55df15a0d29e 338 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 25 327 7.7E-139 T 22-04-2016 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 L21SP4_RS11885 53f863283305f9194acc55df15a0d29e 338 Gene3D G3DSA:1.10.10.10 258 328 3.6E-30 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS11885 53f863283305f9194acc55df15a0d29e 338 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 12 236 1.0E-109 T 22-04-2016 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 L21SP4_RS11885 53f863283305f9194acc55df15a0d29e 338 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 252 322 1.0E-23 T 22-04-2016 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 L21SP4_RS11885 53f863283305f9194acc55df15a0d29e 338 SMART SM00382 52 179 8.0E-12 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS11885 53f863283305f9194acc55df15a0d29e 338 SUPERFAMILY SSF46785 258 331 4.9E-21 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS11885 53f863283305f9194acc55df15a0d29e 338 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 338 157.818 T 22-04-2016 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 L21SP4_RS11885 53f863283305f9194acc55df15a0d29e 338 PANTHER PTHR13779 14 333 1.4E-164 T 22-04-2016 L21SP4_RS11885 53f863283305f9194acc55df15a0d29e 338 SUPERFAMILY SSF52540 20 252 5.82E-56 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS11885 53f863283305f9194acc55df15a0d29e 338 PANTHER PTHR13779:SF25 14 333 1.4E-164 T 22-04-2016 L21SP4_RS11885 53f863283305f9194acc55df15a0d29e 338 Gene3D G3DSA:3.40.50.300 21 173 1.3E-34 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS12140 7e012dfecd2dbecd2ee7427b94ab4628 859 PIRSF PIRSF000111 1 859 0.0 T 22-04-2016 IPR012079 Bifunctional aldehyde-alcohol dehydrogenase GO:0004022|GO:0006066|GO:0008774|GO:0015976|GO:0055114 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00592+1.1.1.1|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00650+1.2.1.10|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7085|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7180|MetaCyc: PWY-7396 L21SP4_RS12140 7e012dfecd2dbecd2ee7427b94ab4628 859 PANTHER PTHR11496 360 857 4.6E-284 T 22-04-2016 L21SP4_RS12140 7e012dfecd2dbecd2ee7427b94ab4628 859 Gene3D G3DSA:3.40.50.1970 449 640 1.1E-61 T 22-04-2016 L21SP4_RS12140 7e012dfecd2dbecd2ee7427b94ab4628 859 Pfam PF00171 Aldehyde dehydrogenase family 6 400 1.3E-21 T 22-04-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 L21SP4_RS12140 7e012dfecd2dbecd2ee7427b94ab4628 859 Pfam PF00465 Iron-containing alcohol dehydrogenase 456 844 5.6E-113 T 22-04-2016 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 L21SP4_RS12140 7e012dfecd2dbecd2ee7427b94ab4628 859 Gene3D G3DSA:3.40.309.10 214 273 3.0E-23 T 22-04-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 L21SP4_RS12140 7e012dfecd2dbecd2ee7427b94ab4628 859 Gene3D G3DSA:3.40.309.10 309 402 3.0E-23 T 22-04-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 L21SP4_RS12140 7e012dfecd2dbecd2ee7427b94ab4628 859 Gene3D G3DSA:1.20.1090.10 641 857 1.8E-68 T 22-04-2016 L21SP4_RS12140 7e012dfecd2dbecd2ee7427b94ab4628 859 Gene3D G3DSA:3.40.605.10 7 206 3.3E-24 T 22-04-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 L21SP4_RS12140 7e012dfecd2dbecd2ee7427b94ab4628 859 SUPERFAMILY SSF56796 447 857 6.8E-121 T 22-04-2016 L21SP4_RS12140 7e012dfecd2dbecd2ee7427b94ab4628 859 SUPERFAMILY SSF53720 9 452 1.96E-78 T 22-04-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 L21SP4_RS12140 7e012dfecd2dbecd2ee7427b94ab4628 859 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 717 737 - T 22-04-2016 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 L21SP4_RS12140 7e012dfecd2dbecd2ee7427b94ab4628 859 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 629 657 - T 22-04-2016 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 L21SP4_RS12140 7e012dfecd2dbecd2ee7427b94ab4628 859 PANTHER PTHR11496:SF79 360 857 4.6E-284 T 22-04-2016 L21SP4_RS02130 5e5f9ac6f9a373165b5387b34764cbfe 307 Gene3D G3DSA:3.50.50.60 116 238 7.0E-33 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP4_RS02130 5e5f9ac6f9a373165b5387b34764cbfe 307 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 291 1.3E-47 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP4_RS02130 5e5f9ac6f9a373165b5387b34764cbfe 307 PANTHER PTHR22912 1 307 2.4E-148 T 22-04-2016 L21SP4_RS02130 5e5f9ac6f9a373165b5387b34764cbfe 307 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 3 302 1.7E-120 T 22-04-2016 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00240+1.8.1.9|KEGG: 00450+1.8.1.9 L21SP4_RS02130 5e5f9ac6f9a373165b5387b34764cbfe 307 PANTHER PTHR22912:SF48 1 307 2.4E-148 T 22-04-2016 L21SP4_RS02130 5e5f9ac6f9a373165b5387b34764cbfe 307 Gene3D G3DSA:3.50.50.60 2 115 1.6E-35 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP4_RS02130 5e5f9ac6f9a373165b5387b34764cbfe 307 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 230 246 3.0E-35 T 22-04-2016 L21SP4_RS02130 5e5f9ac6f9a373165b5387b34764cbfe 307 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 102 120 3.0E-35 T 22-04-2016 L21SP4_RS02130 5e5f9ac6f9a373165b5387b34764cbfe 307 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 255 277 3.0E-35 T 22-04-2016 L21SP4_RS02130 5e5f9ac6f9a373165b5387b34764cbfe 307 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 144 162 3.0E-35 T 22-04-2016 L21SP4_RS02130 5e5f9ac6f9a373165b5387b34764cbfe 307 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 3.0E-35 T 22-04-2016 L21SP4_RS02130 5e5f9ac6f9a373165b5387b34764cbfe 307 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 3 25 7.0E-76 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 L21SP4_RS02130 5e5f9ac6f9a373165b5387b34764cbfe 307 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 125 137 7.0E-76 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 L21SP4_RS02130 5e5f9ac6f9a373165b5387b34764cbfe 307 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 192 208 7.0E-76 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 L21SP4_RS02130 5e5f9ac6f9a373165b5387b34764cbfe 307 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 57 67 7.0E-76 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 L21SP4_RS02130 5e5f9ac6f9a373165b5387b34764cbfe 307 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 232 253 7.0E-76 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 L21SP4_RS02130 5e5f9ac6f9a373165b5387b34764cbfe 307 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 36 51 7.0E-76 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 L21SP4_RS02130 5e5f9ac6f9a373165b5387b34764cbfe 307 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 265 283 7.0E-76 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 L21SP4_RS02130 5e5f9ac6f9a373165b5387b34764cbfe 307 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 103 111 7.0E-76 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 L21SP4_RS02130 5e5f9ac6f9a373165b5387b34764cbfe 307 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 140 164 7.0E-76 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 L21SP4_RS02130 5e5f9ac6f9a373165b5387b34764cbfe 307 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 132 152 - T 22-04-2016 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 L21SP4_RS02130 5e5f9ac6f9a373165b5387b34764cbfe 307 SUPERFAMILY SSF51905 2 303 1.21E-50 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP4_RS09425 15ef03586d359f2238a1d8b3663b8de8 321 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 297 320 4.8E-6 T 22-04-2016 IPR013424 PEP-CTERM protein-sorting domain L21SP4_RS02780 db21e6222775b0e05c4c4d1a6834c8bb 230 Gene3D G3DSA:1.10.150.240 22 68 3.8E-9 T 22-04-2016 IPR023198 Phosphoglycolate phosphatase, domain 2 L21SP4_RS02780 db21e6222775b0e05c4c4d1a6834c8bb 230 Pfam PF13419 Haloacid dehalogenase-like hydrolase 8 188 8.5E-14 T 22-04-2016 IPR023214 HAD-like domain L21SP4_RS02780 db21e6222775b0e05c4c4d1a6834c8bb 230 SUPERFAMILY SSF56784 7 217 2.44E-36 T 22-04-2016 IPR023214 HAD-like domain L21SP4_RS02780 db21e6222775b0e05c4c4d1a6834c8bb 230 PANTHER PTHR18901:SF27 1 217 1.2E-46 T 22-04-2016 L21SP4_RS02780 db21e6222775b0e05c4c4d1a6834c8bb 230 Gene3D G3DSA:3.40.50.1000 88 218 1.7E-25 T 22-04-2016 IPR023214 HAD-like domain L21SP4_RS02780 db21e6222775b0e05c4c4d1a6834c8bb 230 PANTHER PTHR18901 1 217 1.2E-46 T 22-04-2016 L21SP4_RS01760 7f711ca0900d88e13ea3fc39a5df6c7d 220 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 12 32 - T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site L21SP4_RS01760 7f711ca0900d88e13ea3fc39a5df6c7d 220 PANTHER PTHR30093 11 107 2.6E-20 T 22-04-2016 L21SP4_RS01760 7f711ca0900d88e13ea3fc39a5df6c7d 220 Pfam PF13633 Prokaryotic N-terminal methylation site 12 36 4.6E-9 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site L21SP4_RS01760 7f711ca0900d88e13ea3fc39a5df6c7d 220 SUPERFAMILY SSF54523 14 93 3.69E-16 T 22-04-2016 L21SP4_RS01760 7f711ca0900d88e13ea3fc39a5df6c7d 220 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 11 33 8.9E-8 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site L21SP4_RS01760 7f711ca0900d88e13ea3fc39a5df6c7d 220 Gene3D G3DSA:3.30.700.10 14 68 3.4E-9 T 22-04-2016 L21SP4_RS01760 7f711ca0900d88e13ea3fc39a5df6c7d 220 TIGRFAM TIGR04294 pre_pil_HX9DG: prepilin-type processing-associated H-X9-DG domain 185 200 1.6E-4 T 22-04-2016 IPR027558 Prepilin-type processing-associated H-X9-DG domain L21SP4_RS05560 fa7802b96c8d723ad0dee09f4f3acaa8 216 SUPERFAMILY SSF49785 58 215 9.92E-8 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS05560 fa7802b96c8d723ad0dee09f4f3acaa8 216 Gene3D G3DSA:2.60.120.260 66 214 4.7E-10 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS08275 528c425a8f49a549505e6197d239050c 336 Gene3D G3DSA:1.10.150.20 249 323 3.3E-31 T 22-04-2016 L21SP4_RS08275 528c425a8f49a549505e6197d239050c 336 SMART SM00662 25 232 1.8E-76 T 22-04-2016 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 L21SP4_RS08275 528c425a8f49a549505e6197d239050c 336 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 25 320 4.8E-115 T 22-04-2016 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 L21SP4_RS08275 528c425a8f49a549505e6197d239050c 336 PANTHER PTHR32108:SF0 5 334 2.8E-131 T 22-04-2016 L21SP4_RS08275 528c425a8f49a549505e6197d239050c 336 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 261 323 3.0E-18 T 22-04-2016 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 L21SP4_RS08275 528c425a8f49a549505e6197d239050c 336 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 5 321 35.989 T 22-04-2016 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 L21SP4_RS08275 528c425a8f49a549505e6197d239050c 336 SUPERFAMILY SSF47789 256 322 3.27E-24 T 22-04-2016 L21SP4_RS08275 528c425a8f49a549505e6197d239050c 336 SUPERFAMILY SSF55257 177 231 2.35E-28 T 22-04-2016 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 L21SP4_RS08275 528c425a8f49a549505e6197d239050c 336 SUPERFAMILY SSF55257 22 55 2.35E-28 T 22-04-2016 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 L21SP4_RS08275 528c425a8f49a549505e6197d239050c 336 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 66 159 6.9E-19 T 22-04-2016 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 L21SP4_RS08275 528c425a8f49a549505e6197d239050c 336 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 31 226 3.1E-22 T 22-04-2016 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 L21SP4_RS08275 528c425a8f49a549505e6197d239050c 336 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 249 313 3.3E-25 T 22-04-2016 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 L21SP4_RS08275 528c425a8f49a549505e6197d239050c 336 Gene3D G3DSA:3.30.1360.10 176 229 2.5E-32 T 22-04-2016 L21SP4_RS08275 528c425a8f49a549505e6197d239050c 336 Gene3D G3DSA:3.30.1360.10 22 53 2.5E-32 T 22-04-2016 L21SP4_RS08275 528c425a8f49a549505e6197d239050c 336 PANTHER PTHR32108 5 334 2.8E-131 T 22-04-2016 L21SP4_RS08275 528c425a8f49a549505e6197d239050c 336 SUPERFAMILY SSF56553 55 176 5.62E-40 T 22-04-2016 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 L21SP4_RS08275 528c425a8f49a549505e6197d239050c 336 Gene3D G3DSA:2.170.120.12 55 175 3.6E-42 T 22-04-2016 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 L21SP4_RS08305 ff71d2462380f1f6857cc7a1a2c75f13 217 PRINTS PR00094 Adenylate kinase signature 161 176 1.6E-30 T 22-04-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 L21SP4_RS08305 ff71d2462380f1f6857cc7a1a2c75f13 217 PRINTS PR00094 Adenylate kinase signature 82 98 1.6E-30 T 22-04-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 L21SP4_RS08305 ff71d2462380f1f6857cc7a1a2c75f13 217 PRINTS PR00094 Adenylate kinase signature 178 192 1.6E-30 T 22-04-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 L21SP4_RS08305 ff71d2462380f1f6857cc7a1a2c75f13 217 PRINTS PR00094 Adenylate kinase signature 5 18 1.6E-30 T 22-04-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 L21SP4_RS08305 ff71d2462380f1f6857cc7a1a2c75f13 217 PRINTS PR00094 Adenylate kinase signature 33 47 1.6E-30 T 22-04-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 L21SP4_RS08305 ff71d2462380f1f6857cc7a1a2c75f13 217 Hamap MF_00235 Adenylate kinase [adk]. 2 214 43.995 T 22-04-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 L21SP4_RS08305 ff71d2462380f1f6857cc7a1a2c75f13 217 Pfam PF00406 Adenylate kinase 6 191 2.9E-48 T 22-04-2016 L21SP4_RS08305 ff71d2462380f1f6857cc7a1a2c75f13 217 TIGRFAM TIGR01351 adk: adenylate kinase 4 212 7.4E-72 T 22-04-2016 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 L21SP4_RS08305 ff71d2462380f1f6857cc7a1a2c75f13 217 Pfam PF05191 Adenylate kinase, active site lid 128 163 2.9E-17 T 22-04-2016 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 L21SP4_RS08305 ff71d2462380f1f6857cc7a1a2c75f13 217 Gene3D G3DSA:3.40.50.300 4 214 2.0E-68 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS08305 ff71d2462380f1f6857cc7a1a2c75f13 217 PANTHER PTHR23359 4 213 1.1E-83 T 22-04-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 L21SP4_RS08305 ff71d2462380f1f6857cc7a1a2c75f13 217 ProSitePatterns PS00113 Adenylate kinase signature. 82 93 - T 22-04-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 L21SP4_RS08305 ff71d2462380f1f6857cc7a1a2c75f13 217 SUPERFAMILY SSF52540 1 212 1.13E-35 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS01520 0279ec164aa9a5f006c74d57a363d613 149 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 149 73.859 T 22-04-2016 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 L21SP4_RS01520 0279ec164aa9a5f006c74d57a363d613 149 PANTHER PTHR30455 2 149 4.3E-55 T 22-04-2016 L21SP4_RS01520 0279ec164aa9a5f006c74d57a363d613 149 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 146 2.1E-51 T 22-04-2016 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 L21SP4_RS01520 0279ec164aa9a5f006c74d57a363d613 149 PANTHER PTHR30455:SF2 2 149 4.3E-55 T 22-04-2016 L21SP4_RS01520 0279ec164aa9a5f006c74d57a363d613 149 Pfam PF03477 ATP cone domain 50 136 2.0E-16 T 22-04-2016 IPR005144 ATP-cone domain L21SP4_RS05310 a5fb1da8ae244e1dc6e3250aa38b1aee 366 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 364 1.2E-125 T 22-04-2016 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 L21SP4_RS05310 a5fb1da8ae244e1dc6e3250aa38b1aee 366 Gene3D G3DSA:1.10.150.300 132 202 1.3E-16 T 22-04-2016 IPR023192 TGS-like domain L21SP4_RS05310 a5fb1da8ae244e1dc6e3250aa38b1aee 366 PANTHER PTHR23305 1 363 9.5E-158 T 22-04-2016 L21SP4_RS05310 a5fb1da8ae244e1dc6e3250aa38b1aee 366 PIRSF PIRSF006641 1 366 5.3E-134 T 22-04-2016 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 L21SP4_RS05310 a5fb1da8ae244e1dc6e3250aa38b1aee 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 1.3E-31 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 L21SP4_RS05310 a5fb1da8ae244e1dc6e3250aa38b1aee 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 71 86 1.3E-31 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 L21SP4_RS05310 a5fb1da8ae244e1dc6e3250aa38b1aee 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 27 45 1.3E-31 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 L21SP4_RS05310 a5fb1da8ae244e1dc6e3250aa38b1aee 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 88 106 1.3E-31 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 L21SP4_RS05310 a5fb1da8ae244e1dc6e3250aa38b1aee 366 SUPERFAMILY SSF81271 282 362 4.36E-35 T 22-04-2016 IPR012676 TGS-like KEGG: 00970+6.1.1.3 L21SP4_RS05310 a5fb1da8ae244e1dc6e3250aa38b1aee 366 SUPERFAMILY SSF52540 4 304 5.83E-68 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS05310 a5fb1da8ae244e1dc6e3250aa38b1aee 366 Gene3D G3DSA:3.10.20.30 270 363 8.6E-45 T 22-04-2016 IPR012675 Beta-grasp domain L21SP4_RS05310 a5fb1da8ae244e1dc6e3250aa38b1aee 366 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 366 39.722 T 22-04-2016 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 L21SP4_RS05310 a5fb1da8ae244e1dc6e3250aa38b1aee 366 Pfam PF01926 50S ribosome-binding GTPase 5 115 1.5E-21 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 L21SP4_RS05310 a5fb1da8ae244e1dc6e3250aa38b1aee 366 Gene3D G3DSA:3.40.50.300 203 269 5.1E-38 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS05310 a5fb1da8ae244e1dc6e3250aa38b1aee 366 Gene3D G3DSA:3.40.50.300 4 131 5.1E-38 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS05310 a5fb1da8ae244e1dc6e3250aa38b1aee 366 Pfam PF06071 Protein of unknown function (DUF933) 282 363 1.2E-37 T 22-04-2016 IPR013029 Domain of unknown function DUF933 L21SP4_RS05310 a5fb1da8ae244e1dc6e3250aa38b1aee 366 PANTHER PTHR23305:SF12 1 363 9.5E-158 T 22-04-2016 L21SP4_RS00895 a750e6000ea7a2c36888201a21c8f944 412 PANTHER PTHR11228:SF24 246 388 1.0E-108 T 22-04-2016 L21SP4_RS00895 a750e6000ea7a2c36888201a21c8f944 412 PANTHER PTHR11228:SF24 26 222 1.0E-108 T 22-04-2016 L21SP4_RS00895 a750e6000ea7a2c36888201a21c8f944 412 Gene3D G3DSA:3.20.20.70 24 365 2.1E-50 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP4_RS00895 a750e6000ea7a2c36888201a21c8f944 412 Pfam PF13186 Iron-sulfur cluster-binding domain 289 350 2.6E-10 T 22-04-2016 IPR023885 4Fe4S-binding SPASM domain L21SP4_RS00895 a750e6000ea7a2c36888201a21c8f944 412 Pfam PF04055 Radical SAM superfamily 23 190 2.3E-15 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 L21SP4_RS00895 a750e6000ea7a2c36888201a21c8f944 412 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 284 378 4.6E-19 T 22-04-2016 IPR023885 4Fe4S-binding SPASM domain L21SP4_RS00895 a750e6000ea7a2c36888201a21c8f944 412 PANTHER PTHR11228 246 388 1.0E-108 T 22-04-2016 L21SP4_RS00895 a750e6000ea7a2c36888201a21c8f944 412 PANTHER PTHR11228 26 222 1.0E-108 T 22-04-2016 L21SP4_RS00895 a750e6000ea7a2c36888201a21c8f944 412 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 137 412 1.0E-17 T 22-04-2016 L21SP4_RS00895 a750e6000ea7a2c36888201a21c8f944 412 TIGRFAM TIGR03942 sulfatase_rSAM: anaerobic sulfatase maturase 16 397 3.2E-146 T 22-04-2016 IPR023867 Anaerobic sulphatase maturase, radical SAM GO:0016491 L21SP4_RS00895 a750e6000ea7a2c36888201a21c8f944 412 SMART SM00729 16 232 0.0033 T 22-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 L21SP4_RS00895 a750e6000ea7a2c36888201a21c8f944 412 SUPERFAMILY SSF102114 25 359 2.62E-48 T 22-04-2016 L21SP4_RS07275 1574a2140690d77de04088336a712251 757 Pfam PF02449 Beta-galactosidase 133 305 1.8E-10 T 22-04-2016 IPR013529 Glycoside hydrolase, family 42, N-terminal GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP4_RS07275 1574a2140690d77de04088336a712251 757 SUPERFAMILY SSF51445 129 355 2.05E-10 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily L21SP4_RS07275 1574a2140690d77de04088336a712251 757 Gene3D G3DSA:3.20.20.80 123 346 1.6E-22 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP4_RS00080 4813a94e5bde5f738f80b49ed9ed8ef6 459 Gene3D G3DSA:1.10.275.10 7 123 5.8E-42 T 22-04-2016 IPR024083 Fumarase/histidase, N-terminal L21SP4_RS00080 4813a94e5bde5f738f80b49ed9ed8ef6 459 PANTHER PTHR11444 1 459 4.0E-215 T 22-04-2016 IPR000362 Fumarate lyase family L21SP4_RS00080 4813a94e5bde5f738f80b49ed9ed8ef6 459 ProSitePatterns PS00163 Fumarate lyases signature. 298 307 - T 22-04-2016 IPR020557 Fumarate lyase, conserved site GO:0003824 L21SP4_RS00080 4813a94e5bde5f738f80b49ed9ed8ef6 459 SUPERFAMILY SSF48557 16 456 7.54E-100 T 22-04-2016 IPR008948 L-Aspartase-like GO:0003824 L21SP4_RS00080 4813a94e5bde5f738f80b49ed9ed8ef6 459 Pfam PF08328 Adenylosuccinate lyase C-terminal 335 449 1.3E-46 T 22-04-2016 IPR013539 Adenylosuccinate lyase PurB, C-terminal GO:0004018|GO:0006188 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00075 L21SP4_RS00080 4813a94e5bde5f738f80b49ed9ed8ef6 459 Gene3D G3DSA:1.10.40.30 393 449 9.4E-31 T 22-04-2016 L21SP4_RS00080 4813a94e5bde5f738f80b49ed9ed8ef6 459 PRINTS PR00149 Fumarate lyase superfamily signature 255 282 5.9E-18 T 22-04-2016 IPR000362 Fumarate lyase family L21SP4_RS00080 4813a94e5bde5f738f80b49ed9ed8ef6 459 PRINTS PR00149 Fumarate lyase superfamily signature 121 139 5.9E-18 T 22-04-2016 IPR000362 Fumarate lyase family L21SP4_RS00080 4813a94e5bde5f738f80b49ed9ed8ef6 459 PRINTS PR00149 Fumarate lyase superfamily signature 166 184 5.9E-18 T 22-04-2016 IPR000362 Fumarate lyase family L21SP4_RS00080 4813a94e5bde5f738f80b49ed9ed8ef6 459 PRINTS PR00149 Fumarate lyase superfamily signature 298 314 5.9E-18 T 22-04-2016 IPR000362 Fumarate lyase family L21SP4_RS00080 4813a94e5bde5f738f80b49ed9ed8ef6 459 PANTHER PTHR11444:SF17 1 459 4.0E-215 T 22-04-2016 L21SP4_RS00080 4813a94e5bde5f738f80b49ed9ed8ef6 459 Gene3D G3DSA:1.20.200.10 124 392 5.9E-77 T 22-04-2016 L21SP4_RS00080 4813a94e5bde5f738f80b49ed9ed8ef6 459 Pfam PF00206 Lyase 19 316 6.3E-53 T 22-04-2016 IPR022761 Fumarate lyase, N-terminal L21SP4_RS00080 4813a94e5bde5f738f80b49ed9ed8ef6 459 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 17 455 3.6E-114 T 22-04-2016 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00075 L21SP4_RS03575 8b441beaaa4f4fccb7fd9c6da85f7218 708 PANTHER PTHR30332 376 679 2.0E-66 T 22-04-2016 L21SP4_RS03575 8b441beaaa4f4fccb7fd9c6da85f7218 708 Pfam PF00263 Bacterial type II and III secretion system protein 502 663 5.6E-47 T 22-04-2016 IPR004846 Type II/III secretion system GO:0009306 L21SP4_RS03575 8b441beaaa4f4fccb7fd9c6da85f7218 708 PANTHER PTHR30332:SF0 376 679 2.0E-66 T 22-04-2016 L21SP4_RS03575 8b441beaaa4f4fccb7fd9c6da85f7218 708 TIGRFAM TIGR02517 type_II_gspD: type II secretion system protein D 29 673 2.9E-126 T 22-04-2016 IPR013356 Type II secretion system GspD GO:0008565|GO:0015627|GO:0015628|GO:0019867 L21SP4_RS03575 8b441beaaa4f4fccb7fd9c6da85f7218 708 PRINTS PR01032 Gene IV protein signature 521 544 1.1E-6 T 22-04-2016 L21SP4_RS03575 8b441beaaa4f4fccb7fd9c6da85f7218 708 PRINTS PR01032 Gene IV protein signature 591 619 1.1E-6 T 22-04-2016 L21SP4_RS03575 8b441beaaa4f4fccb7fd9c6da85f7218 708 PRINTS PR01032 Gene IV protein signature 644 666 1.1E-6 T 22-04-2016 L21SP4_RS03575 8b441beaaa4f4fccb7fd9c6da85f7218 708 Pfam PF03958 Bacterial type II/III secretion system short domain 193 307 8.3E-10 T 22-04-2016 IPR005644 NolW-like L21SP4_RS03575 8b441beaaa4f4fccb7fd9c6da85f7218 708 Pfam PF03958 Bacterial type II/III secretion system short domain 313 424 4.3E-12 T 22-04-2016 IPR005644 NolW-like L21SP4_RS03575 8b441beaaa4f4fccb7fd9c6da85f7218 708 Pfam PF03958 Bacterial type II/III secretion system short domain 128 188 1.5E-6 T 22-04-2016 IPR005644 NolW-like L21SP4_RS03575 8b441beaaa4f4fccb7fd9c6da85f7218 708 PRINTS PR00811 Bacterial general secretion pathway protein D signature 496 520 2.5E-19 T 22-04-2016 IPR001775 GspD/PilQ family L21SP4_RS03575 8b441beaaa4f4fccb7fd9c6da85f7218 708 PRINTS PR00811 Bacterial general secretion pathway protein D signature 628 646 2.5E-19 T 22-04-2016 IPR001775 GspD/PilQ family L21SP4_RS03575 8b441beaaa4f4fccb7fd9c6da85f7218 708 PRINTS PR00811 Bacterial general secretion pathway protein D signature 651 665 2.5E-19 T 22-04-2016 IPR001775 GspD/PilQ family L21SP4_RS03575 8b441beaaa4f4fccb7fd9c6da85f7218 708 PRINTS PR00811 Bacterial general secretion pathway protein D signature 426 436 2.5E-19 T 22-04-2016 IPR001775 GspD/PilQ family L21SP4_RS07475 f50a5517707f187bbb18a29c129246e2 392 SUPERFAMILY SSF56300 22 313 3.44E-36 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like L21SP4_RS07475 f50a5517707f187bbb18a29c129246e2 392 PANTHER PTHR30337:SF5 21 312 6.4E-45 T 22-04-2016 L21SP4_RS07475 f50a5517707f187bbb18a29c129246e2 392 Gene3D G3DSA:3.60.21.10 21 264 3.4E-39 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like L21SP4_RS07475 f50a5517707f187bbb18a29c129246e2 392 PIRSF PIRSF033093 20 392 1.0E-117 T 22-04-2016 IPR014577 Uncharacterised conserved protein UCP033093, metallophosphoesterase-type L21SP4_RS07475 f50a5517707f187bbb18a29c129246e2 392 Pfam PF00149 Calcineurin-like phosphoesterase 22 183 3.5E-11 T 22-04-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 L21SP4_RS07475 f50a5517707f187bbb18a29c129246e2 392 PANTHER PTHR30337 21 312 6.4E-45 T 22-04-2016 L21SP4_RS05110 0eb02b59a6c61d195806b5bd1116c548 202 Pfam PF00929 Exonuclease 4 156 2.7E-28 T 22-04-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III L21SP4_RS05110 0eb02b59a6c61d195806b5bd1116c548 202 SUPERFAMILY SSF53098 2 170 3.3E-50 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS05110 0eb02b59a6c61d195806b5bd1116c548 202 Gene3D G3DSA:3.30.420.10 1 169 1.9E-52 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS05110 0eb02b59a6c61d195806b5bd1116c548 202 SMART SM00479 2 168 2.9E-38 T 22-04-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III L21SP4_RS05110 0eb02b59a6c61d195806b5bd1116c548 202 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 3 165 4.4E-25 T 22-04-2016 IPR006054 DNA polymerase III, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 L21SP4_RS05110 0eb02b59a6c61d195806b5bd1116c548 202 PANTHER PTHR30231 1 166 7.3E-45 T 22-04-2016 L21SP4_RS05355 26986ccf8b3a5823e03b5c3d57a2145a 152 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 12 143 1.5E-60 T 22-04-2016 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 L21SP4_RS05355 26986ccf8b3a5823e03b5c3d57a2145a 152 SUPERFAMILY SSF51316 10 151 4.24E-62 T 22-04-2016 IPR011057 Mss4-like L21SP4_RS05355 26986ccf8b3a5823e03b5c3d57a2145a 152 Gene3D G3DSA:2.170.150.20 8 150 5.8E-62 T 22-04-2016 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 L21SP4_RS05355 26986ccf8b3a5823e03b5c3d57a2145a 152 Pfam PF01641 SelR domain 15 134 5.6E-49 T 22-04-2016 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 L21SP4_RS05355 26986ccf8b3a5823e03b5c3d57a2145a 152 PANTHER PTHR10173:SF18 15 145 5.3E-53 T 22-04-2016 L21SP4_RS05355 26986ccf8b3a5823e03b5c3d57a2145a 152 Hamap MF_01400 Peptide methionine sulfoxide reductase MsrB [msrB]. 2 135 36.712 T 22-04-2016 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 L21SP4_RS05355 26986ccf8b3a5823e03b5c3d57a2145a 152 PANTHER PTHR10173 15 145 5.3E-53 T 22-04-2016 IPR028427 Peptide methionine sulfoxide reductase GO:0006979|GO:0016671|GO:0030091 L21SP4_RS10160 38bdd96aa380d4660e1a4cba0c17fbc5 265 PANTHER PTHR16458:SF2 31 265 5.3E-24 T 22-04-2016 L21SP4_RS10160 38bdd96aa380d4660e1a4cba0c17fbc5 265 Gene3D G3DSA:3.40.50.150 219 250 2.2E-33 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS10160 38bdd96aa380d4660e1a4cba0c17fbc5 265 Gene3D G3DSA:3.40.50.150 32 180 2.2E-33 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS10160 38bdd96aa380d4660e1a4cba0c17fbc5 265 SUPERFAMILY SSF53335 18 262 6.84E-39 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS10160 38bdd96aa380d4660e1a4cba0c17fbc5 265 PANTHER PTHR16458 31 265 5.3E-24 T 22-04-2016 IPR014369 Glycine/Sarcosine N-methyltransferase GO:0017174 L21SP4_RS10160 38bdd96aa380d4660e1a4cba0c17fbc5 265 Pfam PF13649 Methyltransferase domain 63 160 2.3E-14 T 22-04-2016 L21SP4_RS06375 82671a4a139d0a0c6d4b3b5f0cd22d83 169 PIRSF PIRSF000216 4 169 3.2E-52 T 22-04-2016 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 L21SP4_RS06375 82671a4a139d0a0c6d4b3b5f0cd22d83 169 Gene3D G3DSA:3.40.30.10 83 161 4.6E-12 T 22-04-2016 IPR012336 Thioredoxin-like fold L21SP4_RS06375 82671a4a139d0a0c6d4b3b5f0cd22d83 169 PANTHER PTHR10371 10 166 2.3E-58 T 22-04-2016 L21SP4_RS06375 82671a4a139d0a0c6d4b3b5f0cd22d83 169 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 20 162 1.1E-47 T 22-04-2016 L21SP4_RS06375 82671a4a139d0a0c6d4b3b5f0cd22d83 169 SUPERFAMILY SSF52833 13 165 4.18E-50 T 22-04-2016 IPR012336 Thioredoxin-like fold L21SP4_RS09170 ad689afe442157377166fc823c4b4fde 173 TIGRFAM TIGR02802 Pal_lipo: peptidoglycan-associated lipoprotein 69 170 5.9E-40 T 22-04-2016 IPR014169 Peptidoglycan-associated lipoprotein GO:0009279 L21SP4_RS09170 ad689afe442157377166fc823c4b4fde 173 PRINTS PR01021 OMPA domain signature 101 116 3.0E-15 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 L21SP4_RS09170 ad689afe442157377166fc823c4b4fde 173 PRINTS PR01021 OMPA domain signature 116 132 3.0E-15 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 L21SP4_RS09170 ad689afe442157377166fc823c4b4fde 173 PRINTS PR01021 OMPA domain signature 71 93 3.0E-15 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 L21SP4_RS09170 ad689afe442157377166fc823c4b4fde 173 PANTHER PTHR30128 60 170 6.1E-45 T 22-04-2016 L21SP4_RS09170 ad689afe442157377166fc823c4b4fde 173 PANTHER PTHR30128:SF18 60 170 6.1E-45 T 22-04-2016 L21SP4_RS09170 ad689afe442157377166fc823c4b4fde 173 Gene3D G3DSA:3.30.1330.60 61 171 5.3E-35 T 22-04-2016 IPR006665 OmpA-like domain L21SP4_RS09170 ad689afe442157377166fc823c4b4fde 173 SUPERFAMILY SSF103088 62 171 3.53E-34 T 22-04-2016 IPR006665 OmpA-like domain L21SP4_RS09170 ad689afe442157377166fc823c4b4fde 173 Pfam PF00691 OmpA family 71 165 1.7E-22 T 22-04-2016 IPR006665 OmpA-like domain L21SP4_RS10020 9267f0d8c5a35d8c99658ac9fe64b6ac 114 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 5 110 5.0E-18 T 22-04-2016 IPR003477 mRNA interferase PemK-like protein GO:0003677 L21SP4_RS10020 9267f0d8c5a35d8c99658ac9fe64b6ac 114 PIRSF PIRSF033490 1 114 4.0E-26 T 22-04-2016 IPR003477 mRNA interferase PemK-like protein GO:0003677 L21SP4_RS10020 9267f0d8c5a35d8c99658ac9fe64b6ac 114 SUPERFAMILY SSF50118 1 113 5.4E-25 T 22-04-2016 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor L21SP4_RS10020 9267f0d8c5a35d8c99658ac9fe64b6ac 114 Gene3D G3DSA:2.30.30.110 2 113 2.1E-22 T 22-04-2016 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor L21SP4_RS10020 9267f0d8c5a35d8c99658ac9fe64b6ac 114 PANTHER PTHR33988 1 113 8.7E-26 T 22-04-2016 L21SP4_RS10020 9267f0d8c5a35d8c99658ac9fe64b6ac 114 PANTHER PTHR33988:SF2 1 113 8.7E-26 T 22-04-2016 L21SP4_RS07395 9267f0d8c5a35d8c99658ac9fe64b6ac 114 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 5 110 5.0E-18 T 22-04-2016 IPR003477 mRNA interferase PemK-like protein GO:0003677 L21SP4_RS07395 9267f0d8c5a35d8c99658ac9fe64b6ac 114 PIRSF PIRSF033490 1 114 4.0E-26 T 22-04-2016 IPR003477 mRNA interferase PemK-like protein GO:0003677 L21SP4_RS07395 9267f0d8c5a35d8c99658ac9fe64b6ac 114 SUPERFAMILY SSF50118 1 113 5.4E-25 T 22-04-2016 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor L21SP4_RS07395 9267f0d8c5a35d8c99658ac9fe64b6ac 114 Gene3D G3DSA:2.30.30.110 2 113 2.1E-22 T 22-04-2016 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor L21SP4_RS07395 9267f0d8c5a35d8c99658ac9fe64b6ac 114 PANTHER PTHR33988 1 113 8.7E-26 T 22-04-2016 L21SP4_RS07395 9267f0d8c5a35d8c99658ac9fe64b6ac 114 PANTHER PTHR33988:SF2 1 113 8.7E-26 T 22-04-2016 L21SP4_RS06745 ba876b567e5546aaad66ca05b9adabce 120 PRINTS PR00062 Ribosomal protein L20 signature 12 41 1.51E-33 T 22-04-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 L21SP4_RS06745 ba876b567e5546aaad66ca05b9adabce 120 PRINTS PR00062 Ribosomal protein L20 signature 42 71 1.51E-33 T 22-04-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 L21SP4_RS06745 ba876b567e5546aaad66ca05b9adabce 120 PRINTS PR00062 Ribosomal protein L20 signature 75 101 1.51E-33 T 22-04-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 L21SP4_RS06745 ba876b567e5546aaad66ca05b9adabce 120 PANTHER PTHR10986 2 119 8.6E-46 T 22-04-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 L21SP4_RS06745 ba876b567e5546aaad66ca05b9adabce 120 Gene3D G3DSA:1.10.1900.20 55 118 4.0E-26 T 22-04-2016 L21SP4_RS06745 ba876b567e5546aaad66ca05b9adabce 120 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 23 67 1.0E-9 T 22-04-2016 L21SP4_RS06745 ba876b567e5546aaad66ca05b9adabce 120 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 25.725 T 22-04-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 L21SP4_RS06745 ba876b567e5546aaad66ca05b9adabce 120 SUPERFAMILY SSF74731 3 116 3.53E-39 T 22-04-2016 L21SP4_RS06745 ba876b567e5546aaad66ca05b9adabce 120 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 22-04-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 L21SP4_RS06745 ba876b567e5546aaad66ca05b9adabce 120 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 112 1.6E-43 T 22-04-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 L21SP4_RS06745 ba876b567e5546aaad66ca05b9adabce 120 Pfam PF00453 Ribosomal protein L20 3 109 8.7E-40 T 22-04-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 L21SP4_RS06745 ba876b567e5546aaad66ca05b9adabce 120 PANTHER PTHR10986:SF12 2 119 8.6E-46 T 22-04-2016 L21SP4_RS10025 be3604db12b5ea19db2d8618bf6b71ae 208 SMART SM00382 23 202 1.3E-9 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS10025 be3604db12b5ea19db2d8618bf6b71ae 208 SUPERFAMILY SSF52540 17 206 3.96E-41 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS10025 be3604db12b5ea19db2d8618bf6b71ae 208 PANTHER PTHR24220 19 205 3.6E-40 T 22-04-2016 L21SP4_RS10025 be3604db12b5ea19db2d8618bf6b71ae 208 Pfam PF00005 ABC transporter 17 151 6.3E-22 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 L21SP4_RS10025 be3604db12b5ea19db2d8618bf6b71ae 208 Gene3D G3DSA:3.40.50.300 17 205 1.7E-38 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS00105 2faf69f1c5c04baf20df77773bc638bc 163 Gene3D G3DSA:2.60.40.790 22 161 6.6E-46 T 22-04-2016 IPR008978 HSP20-like chaperone L21SP4_RS00105 2faf69f1c5c04baf20df77773bc638bc 163 PANTHER PTHR11527:SF122 21 161 8.7E-40 T 22-04-2016 L21SP4_RS00105 2faf69f1c5c04baf20df77773bc638bc 163 Pfam PF00011 Hsp20/alpha crystallin family 60 160 8.5E-27 T 22-04-2016 IPR002068 Alpha crystallin/Hsp20 domain L21SP4_RS00105 2faf69f1c5c04baf20df77773bc638bc 163 PANTHER PTHR11527 21 161 8.7E-40 T 22-04-2016 IPR031107 Small heat shock protein HSP20 L21SP4_RS00105 2faf69f1c5c04baf20df77773bc638bc 163 SUPERFAMILY SSF49764 35 160 6.49E-41 T 22-04-2016 IPR008978 HSP20-like chaperone L21SP4_RS05735 bf7095108ac22dd0313eecd409be49ed 440 PANTHER PTHR33258:SF1 316 440 3.0E-73 T 22-04-2016 L21SP4_RS05735 bf7095108ac22dd0313eecd409be49ed 440 PANTHER PTHR33258:SF1 2 263 3.0E-73 T 22-04-2016 L21SP4_RS05735 bf7095108ac22dd0313eecd409be49ed 440 Pfam PF14294 Domain of unknown function (DUF4372) 4 75 9.1E-32 T 22-04-2016 IPR025399 Domain of unknown function DUF4372 L21SP4_RS05735 bf7095108ac22dd0313eecd409be49ed 440 Gene3D G3DSA:3.90.350.10 335 362 8.7E-5 T 22-04-2016 IPR014736 Transposase, Tn5-like, core L21SP4_RS05735 bf7095108ac22dd0313eecd409be49ed 440 Pfam PF01609 Transposase DDE domain 122 385 3.3E-25 T 22-04-2016 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 L21SP4_RS05735 bf7095108ac22dd0313eecd409be49ed 440 SUPERFAMILY SSF53098 272 398 1.44E-28 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS05735 bf7095108ac22dd0313eecd409be49ed 440 SUPERFAMILY SSF53098 92 244 1.44E-28 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS05735 bf7095108ac22dd0313eecd409be49ed 440 PANTHER PTHR33258 316 440 3.0E-73 T 22-04-2016 L21SP4_RS05735 bf7095108ac22dd0313eecd409be49ed 440 PANTHER PTHR33258 2 263 3.0E-73 T 22-04-2016 L21SP4_RS00560 e8323970a48eecffe1acf57885229b6d 218 Gene3D G3DSA:1.10.3210.10 38 160 7.4E-16 T 22-04-2016 IPR006674 HD domain L21SP4_RS00560 e8323970a48eecffe1acf57885229b6d 218 Pfam PF01966 HD domain 39 154 1.3E-10 T 22-04-2016 IPR006674 HD domain L21SP4_RS00560 e8323970a48eecffe1acf57885229b6d 218 SUPERFAMILY SSF109604 38 159 7.33E-17 T 22-04-2016 L21SP4_RS04570 d324e90e9dd584800303f6a3865580a0 487 Pfam PF01565 FAD binding domain 29 156 1.6E-25 T 22-04-2016 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 L21SP4_RS04570 d324e90e9dd584800303f6a3865580a0 487 PANTHER PTHR11748:SF35 189 486 2.6E-77 T 22-04-2016 L21SP4_RS04570 d324e90e9dd584800303f6a3865580a0 487 PANTHER PTHR11748:SF35 55 162 2.6E-77 T 22-04-2016 L21SP4_RS04570 d324e90e9dd584800303f6a3865580a0 487 Pfam PF02913 FAD linked oxidases, C-terminal domain 228 484 2.2E-40 T 22-04-2016 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 L21SP4_RS04570 d324e90e9dd584800303f6a3865580a0 487 SUPERFAMILY SSF56176 15 228 2.37E-41 T 22-04-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 L21SP4_RS04570 d324e90e9dd584800303f6a3865580a0 487 Gene3D G3DSA:3.30.465.10 82 228 4.3E-30 T 22-04-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 L21SP4_RS04570 d324e90e9dd584800303f6a3865580a0 487 PANTHER PTHR11748 189 486 2.6E-77 T 22-04-2016 L21SP4_RS04570 d324e90e9dd584800303f6a3865580a0 487 PANTHER PTHR11748 55 162 2.6E-77 T 22-04-2016 L21SP4_RS04570 d324e90e9dd584800303f6a3865580a0 487 SUPERFAMILY SSF55103 231 486 1.26E-42 T 22-04-2016 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 L21SP4_RS11685 61c67464080d10f92e9e603d52243ef4 366 SUPERFAMILY SSF53098 39 299 7.36E-19 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS11685 61c67464080d10f92e9e603d52243ef4 366 Pfam PF01609 Transposase DDE domain 43 293 5.0E-8 T 22-04-2016 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 L21SP4_RS11685 61c67464080d10f92e9e603d52243ef4 366 Gene3D G3DSA:3.90.350.10 39 275 2.3E-17 T 22-04-2016 IPR014736 Transposase, Tn5-like, core L21SP4_RS10965 03910f2198e57702f016a1401684b1a6 206 Pfam PF01618 MotA/TolQ/ExbB proton channel family 74 179 7.6E-22 T 22-04-2016 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 L21SP4_RS10965 03910f2198e57702f016a1401684b1a6 206 PANTHER PTHR30625 37 196 1.0E-22 T 22-04-2016 L21SP4_RS08235 e3aefac5b37f04f507f3dfe5e8d436e3 356 PANTHER PTHR11933 8 348 3.3E-118 T 22-04-2016 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 L21SP4_RS08235 e3aefac5b37f04f507f3dfe5e8d436e3 356 PANTHER PTHR11933:SF10 8 348 3.3E-118 T 22-04-2016 L21SP4_RS08235 e3aefac5b37f04f507f3dfe5e8d436e3 356 SUPERFAMILY SSF52402 7 239 1.32E-41 T 22-04-2016 L21SP4_RS08235 e3aefac5b37f04f507f3dfe5e8d436e3 356 Gene3D G3DSA:2.30.30.280 214 268 3.4E-11 T 22-04-2016 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 L21SP4_RS08235 e3aefac5b37f04f507f3dfe5e8d436e3 356 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 7 347 1.1E-85 T 22-04-2016 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 L21SP4_RS08235 e3aefac5b37f04f507f3dfe5e8d436e3 356 Gene3D G3DSA:3.40.50.620 4 197 1.6E-64 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP4_RS08235 e3aefac5b37f04f507f3dfe5e8d436e3 356 Gene3D G3DSA:2.40.30.10 271 350 3.2E-26 T 22-04-2016 L21SP4_RS08235 e3aefac5b37f04f507f3dfe5e8d436e3 356 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 6 348 34.263 T 22-04-2016 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 L21SP4_RS08235 e3aefac5b37f04f507f3dfe5e8d436e3 356 Pfam PF03054 tRNA methyl transferase 7 347 4.4E-97 T 22-04-2016 L21SP4_RS12000 83da3334abfb7b0709f4197a711acb96 315 Gene3D G3DSA:1.10.10.60 236 285 3.8E-17 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS12000 83da3334abfb7b0709f4197a711acb96 315 PANTHER PTHR11019:SF11 28 290 1.4E-35 T 22-04-2016 L21SP4_RS12000 83da3334abfb7b0709f4197a711acb96 315 Pfam PF02311 AraC-like ligand binding domain 27 163 1.6E-9 T 22-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 L21SP4_RS12000 83da3334abfb7b0709f4197a711acb96 315 Pfam PF12833 Helix-turn-helix domain 205 283 9.3E-25 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP4_RS12000 83da3334abfb7b0709f4197a711acb96 315 PANTHER PTHR11019 28 290 1.4E-35 T 22-04-2016 L21SP4_RS12000 83da3334abfb7b0709f4197a711acb96 315 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 236 278 - T 22-04-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 L21SP4_RS12000 83da3334abfb7b0709f4197a711acb96 315 SUPERFAMILY SSF46689 184 233 1.61E-9 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS12000 83da3334abfb7b0709f4197a711acb96 315 SMART SM00342 199 282 1.4E-33 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP4_RS12000 83da3334abfb7b0709f4197a711acb96 315 SUPERFAMILY SSF51215 28 169 3.01E-12 T 22-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 L21SP4_RS12000 83da3334abfb7b0709f4197a711acb96 315 SUPERFAMILY SSF46689 235 284 4.26E-13 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS12000 83da3334abfb7b0709f4197a711acb96 315 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 251 266 8.5E-6 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 L21SP4_RS12000 83da3334abfb7b0709f4197a711acb96 315 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 266 282 8.5E-6 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 L21SP4_RS12000 83da3334abfb7b0709f4197a711acb96 315 Gene3D G3DSA:1.10.10.60 184 235 1.3E-15 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS12000 83da3334abfb7b0709f4197a711acb96 315 Gene3D G3DSA:2.60.120.280 28 169 2.8E-11 T 22-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 L21SP4_RS11430 f2360c22f4a8e265f60c34c5336b58b8 292 SUPERFAMILY SSF46689 244 292 9.41E-12 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS11430 f2360c22f4a8e265f60c34c5336b58b8 292 PANTHER PTHR11019 23 292 1.3E-39 T 22-04-2016 L21SP4_RS11430 f2360c22f4a8e265f60c34c5336b58b8 292 Pfam PF12833 Helix-turn-helix domain 214 291 2.5E-20 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP4_RS11430 f2360c22f4a8e265f60c34c5336b58b8 292 Gene3D G3DSA:1.10.10.60 190 246 1.8E-15 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS11430 f2360c22f4a8e265f60c34c5336b58b8 292 PANTHER PTHR11019:SF45 23 292 1.3E-39 T 22-04-2016 L21SP4_RS11430 f2360c22f4a8e265f60c34c5336b58b8 292 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 275 291 8.8E-6 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 L21SP4_RS11430 f2360c22f4a8e265f60c34c5336b58b8 292 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 260 275 8.8E-6 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 L21SP4_RS11430 f2360c22f4a8e265f60c34c5336b58b8 292 SMART SM00342 208 291 6.4E-25 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP4_RS11430 f2360c22f4a8e265f60c34c5336b58b8 292 Pfam PF02311 AraC-like ligand binding domain 40 154 1.2E-21 T 22-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 L21SP4_RS11430 f2360c22f4a8e265f60c34c5336b58b8 292 Gene3D G3DSA:2.60.120.280 18 172 1.3E-29 T 22-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 L21SP4_RS11430 f2360c22f4a8e265f60c34c5336b58b8 292 SUPERFAMILY SSF51215 19 172 4.84E-24 T 22-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 L21SP4_RS11430 f2360c22f4a8e265f60c34c5336b58b8 292 Gene3D G3DSA:1.10.10.60 247 292 3.1E-16 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS11430 f2360c22f4a8e265f60c34c5336b58b8 292 SUPERFAMILY SSF46689 192 242 5.38E-11 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS09020 15e6ddadb0eaba32376d3d7e04929a2a 83 SUPERFAMILY SSF117916 1 82 3.27E-23 T 22-04-2016 L21SP4_RS09020 15e6ddadb0eaba32376d3d7e04929a2a 83 Pfam PF01106 NifU-like domain 16 76 7.3E-22 T 22-04-2016 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 L21SP4_RS09020 15e6ddadb0eaba32376d3d7e04929a2a 83 PANTHER PTHR11178:SF15 1 80 1.1E-15 T 22-04-2016 L21SP4_RS09020 15e6ddadb0eaba32376d3d7e04929a2a 83 PANTHER PTHR11178 1 80 1.1E-15 T 22-04-2016 L21SP4_RS09020 15e6ddadb0eaba32376d3d7e04929a2a 83 ProDom PD002830 NIFU NIFU NITROGEN-FIXING C-TERMINAL FIXATION NITROGEN NIFU-LIKE DOMAIN CLUSTER HESB/YADR/YFHF:NITROGEN-FIXING 18 75 5.0E-9 T 22-04-2016 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 L21SP4_RS03665 0d1497b7480daab57d9ad168611afa71 453 Pfam PF00072 Response regulator receiver domain 5 110 2.7E-26 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 L21SP4_RS03665 0d1497b7480daab57d9ad168611afa71 453 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 166 179 - T 22-04-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 L21SP4_RS03665 0d1497b7480daab57d9ad168611afa71 453 SUPERFAMILY SSF52540 141 385 4.58E-75 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS03665 0d1497b7480daab57d9ad168611afa71 453 Gene3D G3DSA:1.10.10.60 387 450 8.5E-20 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS03665 0d1497b7480daab57d9ad168611afa71 453 SUPERFAMILY SSF46689 355 450 7.47E-17 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS03665 0d1497b7480daab57d9ad168611afa71 453 SMART SM00448 3 113 1.4E-28 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 L21SP4_RS03665 0d1497b7480daab57d9ad168611afa71 453 SMART SM00382 162 305 1.6E-10 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS03665 0d1497b7480daab57d9ad168611afa71 453 Pfam PF00158 Sigma-54 interaction domain 142 308 8.2E-70 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 L21SP4_RS03665 0d1497b7480daab57d9ad168611afa71 453 Gene3D G3DSA:3.40.50.2300 5 134 1.9E-36 T 22-04-2016 L21SP4_RS03665 0d1497b7480daab57d9ad168611afa71 453 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 414 431 5.6E-14 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 L21SP4_RS03665 0d1497b7480daab57d9ad168611afa71 453 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 431 451 5.6E-14 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 L21SP4_RS03665 0d1497b7480daab57d9ad168611afa71 453 PANTHER PTHR32071 5 450 4.9E-199 T 22-04-2016 L21SP4_RS03665 0d1497b7480daab57d9ad168611afa71 453 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 355 364 - T 22-04-2016 IPR025944 Sigma-54 interaction domain, conserved site L21SP4_RS03665 0d1497b7480daab57d9ad168611afa71 453 SUPERFAMILY SSF52172 4 187 7.68E-43 T 22-04-2016 IPR011006 CheY-like superfamily L21SP4_RS03665 0d1497b7480daab57d9ad168611afa71 453 Gene3D G3DSA:1.10.8.60 315 386 2.2E-27 T 22-04-2016 L21SP4_RS03665 0d1497b7480daab57d9ad168611afa71 453 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 228 243 - T 22-04-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 L21SP4_RS03665 0d1497b7480daab57d9ad168611afa71 453 Gene3D G3DSA:3.40.50.300 140 314 2.7E-58 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS03665 0d1497b7480daab57d9ad168611afa71 453 Pfam PF02954 Bacterial regulatory protein, Fis family 407 448 6.6E-16 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 L21SP4_RS10600 6902f5a5ea9ceea71049e266cd46279e 198 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 2 190 6.0E-53 T 22-04-2016 IPR002637 Ham1-like protein GO:0016787 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206 L21SP4_RS10600 6902f5a5ea9ceea71049e266cd46279e 198 Pfam PF01725 Ham1 family 3 187 1.5E-53 T 22-04-2016 IPR002637 Ham1-like protein GO:0016787 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206 L21SP4_RS10600 6902f5a5ea9ceea71049e266cd46279e 198 PANTHER PTHR11067:SF9 1 198 2.5E-72 T 22-04-2016 L21SP4_RS10600 6902f5a5ea9ceea71049e266cd46279e 198 Hamap MF_01405 dITP/XTP pyrophosphatase [rdgB]. 1 192 47.223 T 22-04-2016 IPR020922 Non-canonical purine NTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206 L21SP4_RS10600 6902f5a5ea9ceea71049e266cd46279e 198 SUPERFAMILY SSF52972 1 190 5.23E-65 T 22-04-2016 IPR029001 Inosine triphosphate pyrophosphatase-like L21SP4_RS10600 6902f5a5ea9ceea71049e266cd46279e 198 Gene3D G3DSA:3.90.950.10 1 190 6.2E-74 T 22-04-2016 IPR029001 Inosine triphosphate pyrophosphatase-like L21SP4_RS10600 6902f5a5ea9ceea71049e266cd46279e 198 PANTHER PTHR11067 1 198 2.5E-72 T 22-04-2016 IPR002637 Ham1-like protein GO:0016787 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206 L21SP4_RS06510 9010cbeaf628ebf479d8b31d010d49b1 466 ProSitePatterns PS00523 Sulfatases signature 1. 55 67 - T 22-04-2016 IPR024607 Sulfatase, conserved site L21SP4_RS06510 9010cbeaf628ebf479d8b31d010d49b1 466 Gene3D G3DSA:3.30.1120.10 372 449 1.4E-16 T 22-04-2016 L21SP4_RS06510 9010cbeaf628ebf479d8b31d010d49b1 466 Pfam PF00884 Sulfatase 9 336 7.7E-60 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS06510 9010cbeaf628ebf479d8b31d010d49b1 466 SUPERFAMILY SSF53649 7 438 8.68E-118 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS06510 9010cbeaf628ebf479d8b31d010d49b1 466 PANTHER PTHR10342 7 441 2.4E-106 T 22-04-2016 L21SP4_RS06510 9010cbeaf628ebf479d8b31d010d49b1 466 Gene3D G3DSA:3.40.720.10 7 355 6.5E-99 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS06510 9010cbeaf628ebf479d8b31d010d49b1 466 Pfam PF16347 Domain of unknown function (DUF4976) 338 436 1.1E-7 T 22-04-2016 IPR032506 Domain of unknown function DUF4976 L21SP4_RS06510 9010cbeaf628ebf479d8b31d010d49b1 466 ProSitePatterns PS00149 Sulfatases signature 2. 97 107 - T 22-04-2016 IPR024607 Sulfatase, conserved site L21SP4_RS01905 a4190d0b7cb42ca0c6b5082304548607 433 SUPERFAMILY SSF53067 2 241 1.91E-31 T 22-04-2016 L21SP4_RS01905 a4190d0b7cb42ca0c6b5082304548607 433 Gene3D G3DSA:3.30.420.40 1 237 2.0E-32 T 22-04-2016 L21SP4_RS01905 a4190d0b7cb42ca0c6b5082304548607 433 PANTHER PTHR10196 2 253 1.1E-23 T 22-04-2016 L21SP4_RS01905 a4190d0b7cb42ca0c6b5082304548607 433 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 1 236 1.5E-22 T 22-04-2016 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 L21SP4_RS01905 a4190d0b7cb42ca0c6b5082304548607 433 SUPERFAMILY SSF53067 242 413 6.31E-6 T 22-04-2016 L21SP4_RS08090 8db7a97a7ffe5fc5a80da4d9e625f508 365 SUPERFAMILY SSF51735 23 195 4.09E-48 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS08090 8db7a97a7ffe5fc5a80da4d9e625f508 365 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 28 348 3.3E-95 T 22-04-2016 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 L21SP4_RS08090 8db7a97a7ffe5fc5a80da4d9e625f508 365 PIRSF PIRSF000116 8 344 3.8E-31 T 22-04-2016 IPR014359 Ketol-acid reductoisomerase, bacteria GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 L21SP4_RS08090 8db7a97a7ffe5fc5a80da4d9e625f508 365 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 202 346 7.7E-41 T 22-04-2016 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 L21SP4_RS08090 8db7a97a7ffe5fc5a80da4d9e625f508 365 Gene3D G3DSA:1.10.1040.10 43 346 1.1E-93 T 22-04-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 L21SP4_RS08090 8db7a97a7ffe5fc5a80da4d9e625f508 365 PANTHER PTHR21371 1 357 6.4E-149 T 22-04-2016 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 L21SP4_RS08090 8db7a97a7ffe5fc5a80da4d9e625f508 365 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 27 194 1.6E-47 T 22-04-2016 IPR013116 Acetohydroxy acid isomeroreductase, NADPH-binding domain KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 L21SP4_RS08090 8db7a97a7ffe5fc5a80da4d9e625f508 365 SUPERFAMILY SSF48179 202 357 5.27E-48 T 22-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 L21SP4_RS10535 0987e3973c2bcd474be976593bea2044 360 Gene3D G3DSA:3.40.50.720 6 139 4.8E-38 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS10535 0987e3973c2bcd474be976593bea2044 360 PANTHER PTHR10996:SF161 1 331 6.0E-151 T 22-04-2016 L21SP4_RS10535 0987e3973c2bcd474be976593bea2044 360 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 112 300 9.5E-53 T 22-04-2016 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 L21SP4_RS10535 0987e3973c2bcd474be976593bea2044 360 SUPERFAMILY SSF52283 6 136 3.16E-29 T 22-04-2016 L21SP4_RS10535 0987e3973c2bcd474be976593bea2044 360 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 226 242 - T 22-04-2016 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site L21SP4_RS10535 0987e3973c2bcd474be976593bea2044 360 Gene3D G3DSA:3.40.50.720 140 308 6.3E-48 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS10535 0987e3973c2bcd474be976593bea2044 360 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 6 330 1.2E-24 T 22-04-2016 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 L21SP4_RS10535 0987e3973c2bcd474be976593bea2044 360 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 149 176 - T 22-04-2016 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 L21SP4_RS10535 0987e3973c2bcd474be976593bea2044 360 SUPERFAMILY SSF51735 104 301 5.48E-57 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS10535 0987e3973c2bcd474be976593bea2044 360 PANTHER PTHR10996 1 331 6.0E-151 T 22-04-2016 L21SP4_RS04765 eea060cdf21c08c8b65e1b2fc82a27bd 314 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 10 295 1.4E-66 T 22-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme L21SP4_RS04765 eea060cdf21c08c8b65e1b2fc82a27bd 314 SUPERFAMILY SSF53686 6 306 7.46E-101 T 22-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme L21SP4_RS04765 eea060cdf21c08c8b65e1b2fc82a27bd 314 TIGRFAM TIGR01136 cysKM: cysteine synthase 9 305 1.3E-130 T 22-04-2016 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936|UniPathway: UPA00136 L21SP4_RS04765 eea060cdf21c08c8b65e1b2fc82a27bd 314 PANTHER PTHR10314 8 305 2.2E-150 T 22-04-2016 L21SP4_RS04765 eea060cdf21c08c8b65e1b2fc82a27bd 314 TIGRFAM TIGR01139 cysK: cysteine synthase A 10 305 4.1E-134 T 22-04-2016 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936|UniPathway: UPA00136 L21SP4_RS04765 eea060cdf21c08c8b65e1b2fc82a27bd 314 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 34 52 - T 22-04-2016 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 L21SP4_RS04765 eea060cdf21c08c8b65e1b2fc82a27bd 314 Gene3D G3DSA:3.40.50.1100 137 305 1.1E-75 T 22-04-2016 L21SP4_RS04765 eea060cdf21c08c8b65e1b2fc82a27bd 314 Gene3D G3DSA:3.40.50.1100 39 136 1.4E-40 T 22-04-2016 L21SP4_RS04765 eea060cdf21c08c8b65e1b2fc82a27bd 314 PANTHER PTHR10314:SF110 8 305 2.2E-150 T 22-04-2016 L21SP4_RS04150 700eb6c2bcfe5489f645729c0608c04e 375 Gene3D G3DSA:3.40.640.10 15 244 1.9E-76 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 L21SP4_RS04150 700eb6c2bcfe5489f645729c0608c04e 375 PANTHER PTHR30244:SF15 1 374 3.1E-141 T 22-04-2016 L21SP4_RS04150 700eb6c2bcfe5489f645729c0608c04e 375 PANTHER PTHR30244 1 374 3.1E-141 T 22-04-2016 L21SP4_RS04150 700eb6c2bcfe5489f645729c0608c04e 375 Gene3D G3DSA:3.90.1150.10 246 372 2.2E-43 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 L21SP4_RS04150 700eb6c2bcfe5489f645729c0608c04e 375 SUPERFAMILY SSF53383 12 371 2.85E-106 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase L21SP4_RS04150 700eb6c2bcfe5489f645729c0608c04e 375 PIRSF PIRSF000390 6 374 1.3E-112 T 22-04-2016 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase L21SP4_RS04150 700eb6c2bcfe5489f645729c0608c04e 375 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 16 367 5.2E-117 T 22-04-2016 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase L21SP4_RS05065 fbea4e057a6df3f39cc271691d416e71 301 Pfam PF01259 SAICAR synthetase 17 267 3.6E-97 T 22-04-2016 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074 L21SP4_RS05065 fbea4e057a6df3f39cc271691d416e71 301 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 17 293 5.1E-73 T 22-04-2016 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074 L21SP4_RS05065 fbea4e057a6df3f39cc271691d416e71 301 ProSitePatterns PS01058 SAICAR synthetase signature 2. 205 213 - T 22-04-2016 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074 L21SP4_RS05065 fbea4e057a6df3f39cc271691d416e71 301 PANTHER PTHR11609 1 292 1.7E-114 T 22-04-2016 L21SP4_RS05065 fbea4e057a6df3f39cc271691d416e71 301 Gene3D G3DSA:3.30.470.20 119 247 3.2E-50 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 L21SP4_RS05065 fbea4e057a6df3f39cc271691d416e71 301 Gene3D G3DSA:3.30.200.20 5 118 3.1E-42 T 22-04-2016 L21SP4_RS05065 fbea4e057a6df3f39cc271691d416e71 301 PANTHER PTHR11609:SF6 1 292 1.7E-114 T 22-04-2016 L21SP4_RS05065 fbea4e057a6df3f39cc271691d416e71 301 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 13 292 24.826 T 22-04-2016 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074 L21SP4_RS05065 fbea4e057a6df3f39cc271691d416e71 301 SUPERFAMILY SSF56104 6 294 1.05E-101 T 22-04-2016 L21SP4_RS12020 a9969d448526c5d1a4844bd028511066 408 SUPERFAMILY SSF53822 25 283 3.81E-32 T 22-04-2016 IPR028082 Periplasmic binding protein-like I L21SP4_RS12020 a9969d448526c5d1a4844bd028511066 408 Pfam PF12833 Helix-turn-helix domain 311 387 1.8E-16 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP4_RS12020 a9969d448526c5d1a4844bd028511066 408 Gene3D G3DSA:1.10.10.60 340 388 1.4E-14 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS12020 a9969d448526c5d1a4844bd028511066 408 Gene3D G3DSA:1.10.10.60 286 339 2.4E-5 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS12020 a9969d448526c5d1a4844bd028511066 408 PANTHER PTHR30146:SF24 27 322 1.9E-44 T 22-04-2016 L21SP4_RS12020 a9969d448526c5d1a4844bd028511066 408 PANTHER PTHR30146 27 322 1.9E-44 T 22-04-2016 L21SP4_RS12020 a9969d448526c5d1a4844bd028511066 408 SMART SM00342 303 386 1.0E-17 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP4_RS12020 a9969d448526c5d1a4844bd028511066 408 Pfam PF13377 Periplasmic binding protein-like domain 113 279 2.1E-29 T 22-04-2016 L21SP4_RS12020 a9969d448526c5d1a4844bd028511066 408 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 340 382 - T 22-04-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 L21SP4_RS12020 a9969d448526c5d1a4844bd028511066 408 Gene3D G3DSA:3.40.50.2300 62 112 2.9E-5 T 22-04-2016 L21SP4_RS12020 a9969d448526c5d1a4844bd028511066 408 SUPERFAMILY SSF46689 339 387 2.46E-10 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS12020 a9969d448526c5d1a4844bd028511066 408 Gene3D G3DSA:3.40.50.2300 113 279 4.5E-28 T 22-04-2016 L21SP4_RS08520 eee64703d7db6728704549954cb3963b 263 Pfam PF05690 Thiazole biosynthesis protein ThiG 7 251 2.4E-96 T 22-04-2016 L21SP4_RS08520 eee64703d7db6728704549954cb3963b 263 PANTHER PTHR34266 1 262 1.0E-125 T 22-04-2016 L21SP4_RS08520 eee64703d7db6728704549954cb3963b 263 Gene3D G3DSA:3.20.20.70 5 259 5.2E-56 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP4_RS08520 eee64703d7db6728704549954cb3963b 263 SUPERFAMILY SSF110399 3 241 1.18E-76 T 22-04-2016 IPR008867 Thiazole biosynthesis GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892|UniPathway: UPA00060 L21SP4_RS08520 eee64703d7db6728704549954cb3963b 263 Hamap MF_00443 Thiazole synthase [thiG]. 4 257 39.285 T 22-04-2016 IPR008867 Thiazole biosynthesis GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892|UniPathway: UPA00060 L21SP4_RS10580 25cf16e935e9054134fbb5c4d715a974 414 PANTHER PTHR11562:SF55 28 308 6.3E-64 T 22-04-2016 L21SP4_RS10580 25cf16e935e9054134fbb5c4d715a974 414 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 29 288 3.7E-60 T 22-04-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 L21SP4_RS10580 25cf16e935e9054134fbb5c4d715a974 414 Pfam PF16916 Dimerisation domain of Zinc Transporter 227 299 2.7E-15 T 22-04-2016 IPR027470 Cation efflux protein, cytoplasmic domain L21SP4_RS10580 25cf16e935e9054134fbb5c4d715a974 414 PANTHER PTHR11562 28 308 6.3E-64 T 22-04-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 L21SP4_RS10580 25cf16e935e9054134fbb5c4d715a974 414 SUPERFAMILY SSF160240 224 300 2.75E-15 T 22-04-2016 L21SP4_RS10580 25cf16e935e9054134fbb5c4d715a974 414 Gene3D G3DSA:3.30.70.1350 222 299 9.6E-18 T 22-04-2016 IPR027470 Cation efflux protein, cytoplasmic domain L21SP4_RS10580 25cf16e935e9054134fbb5c4d715a974 414 Pfam PF01545 Cation efflux family 29 220 3.1E-40 T 22-04-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 L21SP4_RS10580 25cf16e935e9054134fbb5c4d715a974 414 SUPERFAMILY SSF161111 25 221 1.57E-47 T 22-04-2016 L21SP4_RS10580 25cf16e935e9054134fbb5c4d715a974 414 Gene3D G3DSA:1.20.1510.10 29 220 2.0E-40 T 22-04-2016 IPR027469 Cation efflux protein transmembrane domain L21SP4_RS01305 1ce9ca5e5cded094e3aa4b3854356cd9 452 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 419 436 2.6E-7 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 L21SP4_RS01305 1ce9ca5e5cded094e3aa4b3854356cd9 452 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 436 452 2.6E-7 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 L21SP4_RS01305 1ce9ca5e5cded094e3aa4b3854356cd9 452 Gene3D G3DSA:3.40.50.300 140 314 5.9E-60 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS01305 1ce9ca5e5cded094e3aa4b3854356cd9 452 Gene3D G3DSA:1.10.10.60 413 450 5.7E-14 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS01305 1ce9ca5e5cded094e3aa4b3854356cd9 452 SUPERFAMILY SSF52540 142 383 1.54E-68 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS01305 1ce9ca5e5cded094e3aa4b3854356cd9 452 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 166 179 - T 22-04-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 L21SP4_RS01305 1ce9ca5e5cded094e3aa4b3854356cd9 452 Pfam PF00158 Sigma-54 interaction domain 142 309 3.6E-70 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 L21SP4_RS01305 1ce9ca5e5cded094e3aa4b3854356cd9 452 SUPERFAMILY SSF46689 354 451 1.52E-11 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS01305 1ce9ca5e5cded094e3aa4b3854356cd9 452 SMART SM00382 162 305 3.1E-12 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS01305 1ce9ca5e5cded094e3aa4b3854356cd9 452 SUPERFAMILY SSF52172 1 187 1.42E-48 T 22-04-2016 IPR011006 CheY-like superfamily L21SP4_RS01305 1ce9ca5e5cded094e3aa4b3854356cd9 452 Gene3D G3DSA:1.10.8.60 315 391 3.1E-19 T 22-04-2016 L21SP4_RS01305 1ce9ca5e5cded094e3aa4b3854356cd9 452 PANTHER PTHR32071 1 450 1.9E-192 T 22-04-2016 L21SP4_RS01305 1ce9ca5e5cded094e3aa4b3854356cd9 452 Pfam PF00072 Response regulator receiver domain 4 113 5.8E-31 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 L21SP4_RS01305 1ce9ca5e5cded094e3aa4b3854356cd9 452 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 354 363 - T 22-04-2016 IPR025944 Sigma-54 interaction domain, conserved site L21SP4_RS01305 1ce9ca5e5cded094e3aa4b3854356cd9 452 Gene3D G3DSA:3.40.50.2300 1 118 4.1E-40 T 22-04-2016 L21SP4_RS01305 1ce9ca5e5cded094e3aa4b3854356cd9 452 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 228 243 - T 22-04-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 L21SP4_RS01305 1ce9ca5e5cded094e3aa4b3854356cd9 452 SMART SM00448 2 113 1.9E-39 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 L21SP4_RS01305 1ce9ca5e5cded094e3aa4b3854356cd9 452 Pfam PF02954 Bacterial regulatory protein, Fis family 414 450 1.1E-11 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 L21SP4_RS06240 4a6f1dc614842ca07fa37984e7dacbbd 156 Pfam PF00137 ATP synthase subunit C 95 150 5.7E-8 T 22-04-2016 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 L21SP4_RS06240 4a6f1dc614842ca07fa37984e7dacbbd 156 Gene3D G3DSA:1.20.120.610 4 150 2.0E-20 T 22-04-2016 L21SP4_RS06240 4a6f1dc614842ca07fa37984e7dacbbd 156 SUPERFAMILY SSF81333 89 150 1.57E-6 T 22-04-2016 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 L21SP4_RS08340 a187b812f02a20111ed31b5a2788279c 61 Pfam PF00253 Ribosomal protein S14p/S29e 9 60 4.0E-25 T 22-04-2016 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS08340 a187b812f02a20111ed31b5a2788279c 61 ProSitePatterns PS00527 Ribosomal protein S14 signature. 23 45 - T 22-04-2016 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 L21SP4_RS08340 a187b812f02a20111ed31b5a2788279c 61 Hamap MF_01364_B 30S ribosomal protein S14 type Z [rpsZ]. 1 61 24.932 T 22-04-2016 IPR023053 Ribosomal protein S14, type Z L21SP4_RS08340 a187b812f02a20111ed31b5a2788279c 61 Gene3D G3DSA:4.10.830.10 3 61 3.5E-25 T 22-04-2016 L21SP4_RS08340 a187b812f02a20111ed31b5a2788279c 61 SUPERFAMILY SSF57716 5 61 3.14E-20 T 22-04-2016 L21SP4_RS08340 a187b812f02a20111ed31b5a2788279c 61 PANTHER PTHR19836 14 61 1.7E-31 T 22-04-2016 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS00745 96623bc25aab5335ebb3295171af2ee2 202 Gene3D G3DSA:1.10.10.640 68 107 5.3E-20 T 22-04-2016 IPR023094 Toluene tolerance protein, alpha-helical L21SP4_RS00745 96623bc25aab5335ebb3295171af2ee2 202 Gene3D G3DSA:1.10.10.640 164 197 5.3E-20 T 22-04-2016 IPR023094 Toluene tolerance protein, alpha-helical L21SP4_RS00745 96623bc25aab5335ebb3295171af2ee2 202 PIRSF PIRSF004649 1 202 3.4E-44 T 22-04-2016 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC L21SP4_RS00745 96623bc25aab5335ebb3295171af2ee2 202 PANTHER PTHR36573 1 200 1.7E-31 T 22-04-2016 L21SP4_RS00745 96623bc25aab5335ebb3295171af2ee2 202 Gene3D G3DSA:3.10.450.50 31 66 2.2E-11 T 22-04-2016 IPR032710 NTF2-like domain L21SP4_RS00745 96623bc25aab5335ebb3295171af2ee2 202 Gene3D G3DSA:3.10.450.50 110 163 2.2E-11 T 22-04-2016 IPR032710 NTF2-like domain L21SP4_RS00745 96623bc25aab5335ebb3295171af2ee2 202 Pfam PF05494 MlaC protein 34 190 4.6E-42 T 22-04-2016 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC L21SP4_RS09380 70bfb5f3cb4e646950cf566503dfec0b 380 Pfam PF12833 Helix-turn-helix domain 298 374 8.1E-19 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP4_RS09380 70bfb5f3cb4e646950cf566503dfec0b 380 PANTHER PTHR30146 1 309 3.3E-57 T 22-04-2016 L21SP4_RS09380 70bfb5f3cb4e646950cf566503dfec0b 380 SMART SM00342 290 373 1.4E-24 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP4_RS09380 70bfb5f3cb4e646950cf566503dfec0b 380 Gene3D G3DSA:3.40.50.2300 100 266 6.2E-29 T 22-04-2016 L21SP4_RS09380 70bfb5f3cb4e646950cf566503dfec0b 380 SUPERFAMILY SSF46689 326 376 2.37E-11 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS09380 70bfb5f3cb4e646950cf566503dfec0b 380 SUPERFAMILY SSF53822 7 247 5.35E-30 T 22-04-2016 IPR028082 Periplasmic binding protein-like I L21SP4_RS09380 70bfb5f3cb4e646950cf566503dfec0b 380 Pfam PF13377 Periplasmic binding protein-like domain 99 266 1.2E-29 T 22-04-2016 L21SP4_RS09380 70bfb5f3cb4e646950cf566503dfec0b 380 Gene3D G3DSA:1.10.10.60 272 326 1.1E-8 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS09380 70bfb5f3cb4e646950cf566503dfec0b 380 Gene3D G3DSA:1.10.10.60 327 376 2.5E-14 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS09380 70bfb5f3cb4e646950cf566503dfec0b 380 Gene3D G3DSA:3.40.50.2300 44 99 2.4E-8 T 22-04-2016 L21SP4_RS09380 70bfb5f3cb4e646950cf566503dfec0b 380 SUPERFAMILY SSF46689 273 321 1.65E-5 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS09380 70bfb5f3cb4e646950cf566503dfec0b 380 PANTHER PTHR30146:SF24 1 309 3.3E-57 T 22-04-2016 L21SP4_RS08985 4dcfcea0030ae072c1031c822d8ca8ad 496 PANTHER PTHR33908 1 377 8.1E-44 T 22-04-2016 L21SP4_RS08985 4dcfcea0030ae072c1031c822d8ca8ad 496 PANTHER PTHR33908:SF1 1 377 8.1E-44 T 22-04-2016 L21SP4_RS08985 4dcfcea0030ae072c1031c822d8ca8ad 496 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 41 202 2.1E-27 T 22-04-2016 L21SP4_RS08200 37d73ed94d9e0d0ee9967591f90edf5a 363 PANTHER PTHR10584 1 353 9.3E-83 T 22-04-2016 L21SP4_RS08200 37d73ed94d9e0d0ee9967591f90edf5a 363 Pfam PF00294 pfkB family carbohydrate kinase 28 333 1.4E-28 T 22-04-2016 IPR011611 Carbohydrate kinase PfkB L21SP4_RS08200 37d73ed94d9e0d0ee9967591f90edf5a 363 SUPERFAMILY SSF53613 1 353 7.29E-65 T 22-04-2016 IPR029056 Ribokinase-like L21SP4_RS08200 37d73ed94d9e0d0ee9967591f90edf5a 363 Gene3D G3DSA:3.40.1190.20 1 357 1.0E-73 T 22-04-2016 IPR029056 Ribokinase-like L21SP4_RS08200 37d73ed94d9e0d0ee9967591f90edf5a 363 PANTHER PTHR10584:SF203 1 353 9.3E-83 T 22-04-2016 L21SP4_RS03165 fd5a981173f0afa6c2a7c8554a5678d9 344 PANTHER PTHR21091:SF2 167 342 3.8E-13 T 22-04-2016 L21SP4_RS03165 fd5a981173f0afa6c2a7c8554a5678d9 344 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 5 340 1.6E-44 T 22-04-2016 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 L21SP4_RS03165 fd5a981173f0afa6c2a7c8554a5678d9 344 Gene3D G3DSA:3.20.20.210 6 342 5.6E-43 T 22-04-2016 L21SP4_RS03165 fd5a981173f0afa6c2a7c8554a5678d9 344 SUPERFAMILY SSF51726 4 342 9.77E-40 T 22-04-2016 L21SP4_RS03165 fd5a981173f0afa6c2a7c8554a5678d9 344 PANTHER PTHR21091 167 342 3.8E-13 T 22-04-2016 L21SP4_RS06290 c966ffb902aa3ca55c8f5aab015fdfc8 263 TIGRFAM TIGR00444 mazG: MazG family protein 15 260 9.1E-89 T 22-04-2016 IPR011551 NTP pyrophosphohydrolase MazG L21SP4_RS06290 c966ffb902aa3ca55c8f5aab015fdfc8 263 SUPERFAMILY SSF101386 9 106 2.76E-25 T 22-04-2016 L21SP4_RS06290 c966ffb902aa3ca55c8f5aab015fdfc8 263 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 169 229 1.6E-7 T 22-04-2016 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core L21SP4_RS06290 c966ffb902aa3ca55c8f5aab015fdfc8 263 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 31 104 2.4E-27 T 22-04-2016 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core L21SP4_RS06290 c966ffb902aa3ca55c8f5aab015fdfc8 263 PANTHER PTHR30522 8 263 6.5E-106 T 22-04-2016 L21SP4_RS06290 c966ffb902aa3ca55c8f5aab015fdfc8 263 SUPERFAMILY SSF101386 139 238 5.79E-22 T 22-04-2016 L21SP4_RS06290 c966ffb902aa3ca55c8f5aab015fdfc8 263 PANTHER PTHR30522:SF0 8 263 6.5E-106 T 22-04-2016 IPR011551 NTP pyrophosphohydrolase MazG L21SP4_RS06290 c966ffb902aa3ca55c8f5aab015fdfc8 263 Gene3D G3DSA:1.10.287.1080 135 220 6.0E-12 T 22-04-2016 L21SP4_RS06290 c966ffb902aa3ca55c8f5aab015fdfc8 263 Gene3D G3DSA:1.10.287.1080 9 79 4.0E-10 T 22-04-2016 L21SP4_RS02260 82147e6870ea764daa5275a72dae964e 308 SUPERFAMILY SSF53474 249 304 4.78E-30 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold L21SP4_RS02260 82147e6870ea764daa5275a72dae964e 308 SUPERFAMILY SSF53474 25 200 4.78E-30 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold L21SP4_RS02260 82147e6870ea764daa5275a72dae964e 308 Pfam PF10503 Esterase PHB depolymerase 37 184 1.8E-10 T 22-04-2016 IPR010126 Esterase, PHB depolymerase GO:0005576 L21SP4_RS02260 82147e6870ea764daa5275a72dae964e 308 PANTHER PTHR10655:SF33 28 201 4.2E-36 T 22-04-2016 L21SP4_RS02260 82147e6870ea764daa5275a72dae964e 308 Gene3D G3DSA:3.40.50.1820 28 307 4.0E-40 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold L21SP4_RS02260 82147e6870ea764daa5275a72dae964e 308 PANTHER PTHR10655 28 201 4.2E-36 T 22-04-2016 L21SP4_RS04840 d30c61dc155b7f7155568938f4541236 363 PANTHER PTHR33529:SF2 1 363 1.4E-61 T 22-04-2016 L21SP4_RS04840 d30c61dc155b7f7155568938f4541236 363 PANTHER PTHR33529 1 363 1.4E-61 T 22-04-2016 L21SP4_RS04840 d30c61dc155b7f7155568938f4541236 363 Pfam PF03739 Predicted permease YjgP/YjgQ family 6 361 6.6E-61 T 22-04-2016 IPR005495 Permease LptG/LptF-related GO:0016021 L21SP4_RS04430 7a3a66500523477f8377ec77a2463786 879 Gene3D G3DSA:1.50.10.10 626 672 5.7E-5 T 22-04-2016 IPR012341 Six-hairpin glycosidase GO:0003824 L21SP4_RS04430 7a3a66500523477f8377ec77a2463786 879 SUPERFAMILY SSF49785 62 144 2.72E-5 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS04430 7a3a66500523477f8377ec77a2463786 879 PANTHER PTHR34987 411 853 2.7E-43 T 22-04-2016 L21SP4_RS04430 7a3a66500523477f8377ec77a2463786 879 PANTHER PTHR34987:SF1 411 853 2.7E-43 T 22-04-2016 L21SP4_RS04430 7a3a66500523477f8377ec77a2463786 879 Pfam PF08531 Alpha-L-rhamnosidase N-terminal domain 84 219 8.3E-11 T 22-04-2016 IPR013737 Bacterial alpha-L-rhamnosidase N-terminal L21SP4_RS04430 7a3a66500523477f8377ec77a2463786 879 Gene3D G3DSA:2.60.120.260 67 142 2.2E-5 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS04430 7a3a66500523477f8377ec77a2463786 879 SUPERFAMILY SSF48208 441 876 3.4E-39 T 22-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP4_RS04430 7a3a66500523477f8377ec77a2463786 879 Pfam PF05592 Bacterial alpha-L-rhamnosidase 329 855 5.3E-53 T 22-04-2016 IPR008902 Bacterial alpha-L-rhamnosidase L21SP4_RS08655 80c25424651d5d755c6cb6738d2cf61c 151 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 8 140 4.0E-18 T 22-04-2016 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 L21SP4_RS08655 80c25424651d5d755c6cb6738d2cf61c 151 Pfam PF02381 MraZ protein, putative antitoxin-like 9 80 3.9E-8 T 22-04-2016 IPR020603 MraZ domain L21SP4_RS08655 80c25424651d5d755c6cb6738d2cf61c 151 Pfam PF02381 MraZ protein, putative antitoxin-like 85 145 2.0E-9 T 22-04-2016 IPR020603 MraZ domain L21SP4_RS08655 80c25424651d5d755c6cb6738d2cf61c 151 PANTHER PTHR34701 9 141 1.1E-29 T 22-04-2016 L21SP4_RS08655 80c25424651d5d755c6cb6738d2cf61c 151 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 151 32.986 T 22-04-2016 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 L21SP4_RS08655 80c25424651d5d755c6cb6738d2cf61c 151 SUPERFAMILY SSF89447 8 138 5.44E-35 T 22-04-2016 L21SP4_RS03800 5778e7f3f37fd926a8a53e3b4a11b184 1042 SUPERFAMILY SSF51445 305 605 1.17E-36 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily L21SP4_RS03800 5778e7f3f37fd926a8a53e3b4a11b184 1042 SUPERFAMILY SSF49785 29 166 9.22E-11 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS03800 5778e7f3f37fd926a8a53e3b4a11b184 1042 PANTHER PTHR22762:SF7 884 1041 2.4E-54 T 22-04-2016 L21SP4_RS03800 5778e7f3f37fd926a8a53e3b4a11b184 1042 PANTHER PTHR22762:SF7 305 630 2.4E-54 T 22-04-2016 L21SP4_RS03800 5778e7f3f37fd926a8a53e3b4a11b184 1042 PANTHER PTHR22762:SF7 657 683 2.4E-54 T 22-04-2016 L21SP4_RS03800 5778e7f3f37fd926a8a53e3b4a11b184 1042 Pfam PF01055 Glycosyl hydrolases family 31 305 672 1.1E-55 T 22-04-2016 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 L21SP4_RS03800 5778e7f3f37fd926a8a53e3b4a11b184 1042 Gene3D G3DSA:2.60.120.260 30 166 2.5E-8 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS03800 5778e7f3f37fd926a8a53e3b4a11b184 1042 PANTHER PTHR22762 884 1041 2.4E-54 T 22-04-2016 L21SP4_RS03800 5778e7f3f37fd926a8a53e3b4a11b184 1042 PANTHER PTHR22762 305 630 2.4E-54 T 22-04-2016 L21SP4_RS03800 5778e7f3f37fd926a8a53e3b4a11b184 1042 PANTHER PTHR22762 657 683 2.4E-54 T 22-04-2016 L21SP4_RS03800 5778e7f3f37fd926a8a53e3b4a11b184 1042 Pfam PF17137 Domain of unknown function (DUF5110) 925 998 7.1E-14 T 22-04-2016 IPR033403 Domain of unknown function DUF5110 L21SP4_RS05985 9c7dbe36fdc8703956f6cb6c665447d4 531 Gene3D G3DSA:3.40.720.10 12 176 2.3E-92 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS05985 9c7dbe36fdc8703956f6cb6c665447d4 531 Gene3D G3DSA:3.40.720.10 213 438 2.3E-92 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS05985 9c7dbe36fdc8703956f6cb6c665447d4 531 Gene3D G3DSA:3.30.1120.10 473 528 4.8E-13 T 22-04-2016 L21SP4_RS05985 9c7dbe36fdc8703956f6cb6c665447d4 531 PANTHER PTHR10342 220 456 5.6E-122 T 22-04-2016 L21SP4_RS05985 9c7dbe36fdc8703956f6cb6c665447d4 531 PANTHER PTHR10342 1 170 5.6E-122 T 22-04-2016 L21SP4_RS05985 9c7dbe36fdc8703956f6cb6c665447d4 531 PANTHER PTHR10342:SF207 220 456 5.6E-122 T 22-04-2016 L21SP4_RS05985 9c7dbe36fdc8703956f6cb6c665447d4 531 PANTHER PTHR10342:SF207 1 170 5.6E-122 T 22-04-2016 L21SP4_RS05985 9c7dbe36fdc8703956f6cb6c665447d4 531 PANTHER PTHR10342 473 526 5.6E-122 T 22-04-2016 L21SP4_RS05985 9c7dbe36fdc8703956f6cb6c665447d4 531 PANTHER PTHR10342:SF207 473 526 5.6E-122 T 22-04-2016 L21SP4_RS05985 9c7dbe36fdc8703956f6cb6c665447d4 531 Pfam PF00884 Sulfatase 15 416 1.1E-55 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS05985 9c7dbe36fdc8703956f6cb6c665447d4 531 SUPERFAMILY SSF53649 14 156 5.82E-109 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS05985 9c7dbe36fdc8703956f6cb6c665447d4 531 SUPERFAMILY SSF53649 196 527 5.82E-109 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS00615 f7ec5097f6b2301fc8c2356a25b88a27 211 Gene3D G3DSA:3.40.50.150 8 209 3.6E-32 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS00615 f7ec5097f6b2301fc8c2356a25b88a27 211 Pfam PF08241 Methyltransferase domain 44 129 8.2E-16 T 22-04-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 L21SP4_RS00615 f7ec5097f6b2301fc8c2356a25b88a27 211 SUPERFAMILY SSF53335 7 182 3.1E-32 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS00615 f7ec5097f6b2301fc8c2356a25b88a27 211 PANTHER PTHR10108:SF834 7 182 9.5E-27 T 22-04-2016 L21SP4_RS00615 f7ec5097f6b2301fc8c2356a25b88a27 211 PANTHER PTHR10108 7 182 9.5E-27 T 22-04-2016 L21SP4_RS01665 f8f160a317655504c2aab47512c890c6 250 PANTHER PTHR20858:SF17 2 249 5.2E-88 T 22-04-2016 L21SP4_RS01665 f8f160a317655504c2aab47512c890c6 250 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 1 249 1.3E-79 T 22-04-2016 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 L21SP4_RS01665 f8f160a317655504c2aab47512c890c6 250 PANTHER PTHR20858 2 249 5.2E-88 T 22-04-2016 L21SP4_RS01665 f8f160a317655504c2aab47512c890c6 250 SUPERFAMILY SSF53613 2 249 7.95E-68 T 22-04-2016 IPR029056 Ribokinase-like L21SP4_RS01665 f8f160a317655504c2aab47512c890c6 250 Gene3D G3DSA:3.40.1190.20 2 249 7.8E-87 T 22-04-2016 IPR029056 Ribokinase-like L21SP4_RS01665 f8f160a317655504c2aab47512c890c6 250 Pfam PF08543 Phosphomethylpyrimidine kinase 5 249 6.2E-80 T 22-04-2016 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase UniPathway: UPA00647 L21SP4_RS06855 bcd88694be5c058d7a8737663e365a3f 805 SUPERFAMILY SSF49785 656 803 5.1E-8 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS06855 bcd88694be5c058d7a8737663e365a3f 805 Gene3D G3DSA:2.60.120.260 653 802 3.5E-7 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS06855 bcd88694be5c058d7a8737663e365a3f 805 SUPERFAMILY SSF48230 175 339 1.83E-19 T 22-04-2016 IPR008929 Chondroitin AC/alginate lyase L21SP4_RS06855 bcd88694be5c058d7a8737663e365a3f 805 Pfam PF07940 Heparinase II/III-like protein 417 568 5.0E-9 T 22-04-2016 IPR012480 Heparinase II/III-like MetaCyc: PWY-7651 L21SP4_RS10420 f39a2e463e17f33caf6af318daf765e8 277 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 112 229 2.0E-39 T 22-04-2016 IPR003390 DNA integrity scanning protein, DisA, N-terminal L21SP4_RS10420 f39a2e463e17f33caf6af318daf765e8 277 PANTHER PTHR34185:SF1 1 270 4.6E-79 T 22-04-2016 L21SP4_RS10420 f39a2e463e17f33caf6af318daf765e8 277 Gene3D G3DSA:3.40.1700.10 106 233 8.5E-46 T 22-04-2016 L21SP4_RS10420 f39a2e463e17f33caf6af318daf765e8 277 PANTHER PTHR34185 1 270 4.6E-79 T 22-04-2016 L21SP4_RS10420 f39a2e463e17f33caf6af318daf765e8 277 SUPERFAMILY SSF143597 42 232 1.7E-59 T 22-04-2016 L21SP4_RS10420 f39a2e463e17f33caf6af318daf765e8 277 TIGRFAM TIGR00159 TIGR00159: TIGR00159 family protein 11 244 4.0E-69 T 22-04-2016 IPR014046 Diadenylate cyclase-like L21SP4_RS10420 f39a2e463e17f33caf6af318daf765e8 277 PIRSF PIRSF004793 5 260 3.0E-78 T 22-04-2016 IPR014046 Diadenylate cyclase-like L21SP4_RS08505 a08fd24528d19ebb0e267ba136a2ce8d 218 Gene3D G3DSA:3.20.20.70 19 215 5.5E-54 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP4_RS08505 a08fd24528d19ebb0e267ba136a2ce8d 218 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 20 210 5.5E-47 T 22-04-2016 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357|UniPathway: UPA00060 L21SP4_RS08505 a08fd24528d19ebb0e267ba136a2ce8d 218 SUPERFAMILY SSF51391 19 213 4.45E-50 T 22-04-2016 IPR022998 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357|UniPathway: UPA00060 L21SP4_RS08505 a08fd24528d19ebb0e267ba136a2ce8d 218 Pfam PF02581 Thiamine monophosphate synthase/TENI 30 199 5.9E-49 T 22-04-2016 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357|UniPathway: UPA00060 L21SP4_RS08505 a08fd24528d19ebb0e267ba136a2ce8d 218 PANTHER PTHR20857 20 212 2.1E-49 T 22-04-2016 L21SP4_RS08505 a08fd24528d19ebb0e267ba136a2ce8d 218 PANTHER PTHR20857:SF15 20 212 2.1E-49 T 22-04-2016 L21SP4_RS08505 a08fd24528d19ebb0e267ba136a2ce8d 218 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 18 217 21.648 T 22-04-2016 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357|UniPathway: UPA00060 L21SP4_RS06035 6f0c4adac1c6eacca1aff8c1c15e2c24 325 SUPERFAMILY SSF51735 5 159 1.16E-47 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS06035 6f0c4adac1c6eacca1aff8c1c15e2c24 325 Gene3D G3DSA:3.40.50.720 4 148 5.6E-45 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS06035 6f0c4adac1c6eacca1aff8c1c15e2c24 325 PANTHER PTHR22604:SF105 7 325 4.2E-89 T 22-04-2016 L21SP4_RS06035 6f0c4adac1c6eacca1aff8c1c15e2c24 325 SUPERFAMILY SSF55347 132 297 5.56E-34 T 22-04-2016 L21SP4_RS06035 6f0c4adac1c6eacca1aff8c1c15e2c24 325 PANTHER PTHR22604 7 325 4.2E-89 T 22-04-2016 L21SP4_RS06035 6f0c4adac1c6eacca1aff8c1c15e2c24 325 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 7 121 1.2E-23 T 22-04-2016 IPR000683 Oxidoreductase, N-terminal GO:0016491 L21SP4_RS06035 6f0c4adac1c6eacca1aff8c1c15e2c24 325 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 141 205 6.4E-4 T 22-04-2016 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 L21SP4_RS06035 6f0c4adac1c6eacca1aff8c1c15e2c24 325 Gene3D G3DSA:3.30.360.10 149 325 1.7E-42 T 22-04-2016 L21SP4_RS00260 f206cd6c5acc82fd267aeca925daf79b 104 PANTHER PTHR33154 1 101 5.6E-26 T 22-04-2016 L21SP4_RS00260 f206cd6c5acc82fd267aeca925daf79b 104 Pfam PF12840 Helix-turn-helix domain 10 68 6.8E-14 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS00260 f206cd6c5acc82fd267aeca925daf79b 104 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 32 43 3.6E-13 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 L21SP4_RS00260 f206cd6c5acc82fd267aeca925daf79b 104 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 3.6E-13 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 L21SP4_RS00260 f206cd6c5acc82fd267aeca925daf79b 104 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 13 28 3.6E-13 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 L21SP4_RS00260 f206cd6c5acc82fd267aeca925daf79b 104 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 3.6E-13 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 L21SP4_RS00260 f206cd6c5acc82fd267aeca925daf79b 104 Gene3D G3DSA:1.10.10.10 1 95 2.5E-27 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS00260 f206cd6c5acc82fd267aeca925daf79b 104 SMART SM00418 11 86 3.4E-17 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 L21SP4_RS00260 f206cd6c5acc82fd267aeca925daf79b 104 SUPERFAMILY SSF46785 1 100 7.39E-24 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS05405 bc43da5e75a890d4f13539113113821f 114 SUPERFAMILY SSF56935 33 102 3.2E-12 T 22-04-2016 L21SP4_RS05405 bc43da5e75a890d4f13539113113821f 114 Pfam PF07715 TonB-dependent Receptor Plug Domain 46 104 2.6E-5 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 L21SP4_RS05405 bc43da5e75a890d4f13539113113821f 114 Gene3D G3DSA:2.170.130.10 24 108 1.7E-13 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 L21SP4_RS07075 d0f269d114a9d1c6d2b64f4a66faea35 124 ProDom PD076485 YNEG CYTOPLASMIC ECS2130 STY1535 13 115 4.0E-28 T 22-04-2016 IPR020378 Protein of unknown function DUF4186 L21SP4_RS07075 d0f269d114a9d1c6d2b64f4a66faea35 124 Pfam PF13811 Domain of unknown function (DUF4186) 9 115 7.1E-44 T 22-04-2016 IPR020378 Protein of unknown function DUF4186 L21SP4_RS10280 1684647f048b15d5634ced832ab11446 395 PANTHER PTHR11877:SF26 2 390 1.2E-76 T 22-04-2016 L21SP4_RS10280 1684647f048b15d5634ced832ab11446 395 PANTHER PTHR11877 2 390 1.2E-76 T 22-04-2016 L21SP4_RS10280 1684647f048b15d5634ced832ab11446 395 SUPERFAMILY SSF53901 169 388 1.6E-58 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 L21SP4_RS10280 1684647f048b15d5634ced832ab11446 395 Gene3D G3DSA:3.40.47.10 1 249 4.7E-76 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 L21SP4_RS10280 1684647f048b15d5634ced832ab11446 395 TIGRFAM TIGR01835 HMG-CoA-S_prok: hydroxymethylglutaryl-CoA synthase 3 385 1.5E-138 T 22-04-2016 IPR011554 Hydroxymethylglutaryl-CoA synthase, prokaryotic KEGG: 00072+2.3.3.10|KEGG: 00280+2.3.3.10|KEGG: 00650+2.3.3.10|KEGG: 00900+2.3.3.10|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7571|MetaCyc: PWY-922|UniPathway: UPA00058 L21SP4_RS10280 1684647f048b15d5634ced832ab11446 395 Pfam PF01154 Hydroxymethylglutaryl-coenzyme A synthase N terminal 2 164 9.0E-14 T 22-04-2016 IPR013528 Hydroxymethylglutaryl-coenzyme A synthase, N-terminal GO:0004421|GO:0008299 Reactome: REACT_22258 L21SP4_RS10280 1684647f048b15d5634ced832ab11446 395 SUPERFAMILY SSF53901 2 166 4.39E-37 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 L21SP4_RS10280 1684647f048b15d5634ced832ab11446 395 Pfam PF08540 Hydroxymethylglutaryl-coenzyme A synthase C terminal 176 248 2.2E-6 T 22-04-2016 IPR013746 Hydroxymethylglutaryl-coenzyme A synthase C-terminal domain GO:0004421|GO:0008299 KEGG: 00072+2.3.3.10|KEGG: 00280+2.3.3.10|KEGG: 00650+2.3.3.10|KEGG: 00900+2.3.3.10|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7571|MetaCyc: PWY-922|Reactome: REACT_22258|UniPathway: UPA00058 L21SP4_RS10280 1684647f048b15d5634ced832ab11446 395 Pfam PF08540 Hydroxymethylglutaryl-coenzyme A synthase C terminal 271 348 7.9E-10 T 22-04-2016 IPR013746 Hydroxymethylglutaryl-coenzyme A synthase C-terminal domain GO:0004421|GO:0008299 KEGG: 00072+2.3.3.10|KEGG: 00280+2.3.3.10|KEGG: 00650+2.3.3.10|KEGG: 00900+2.3.3.10|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7571|MetaCyc: PWY-922|Reactome: REACT_22258|UniPathway: UPA00058 L21SP4_RS05900 51a7b0bd9134973fcfb0225d77f26acf 385 Hamap MF_00409 Tetraacyldisaccharide 4'-kinase [lpxK]. 7 384 26.795 T 22-04-2016 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130|UniPathway: UPA00359 L21SP4_RS05900 51a7b0bd9134973fcfb0225d77f26acf 385 Pfam PF02606 Tetraacyldisaccharide-1-P 4'-kinase 31 381 4.2E-80 T 22-04-2016 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130|UniPathway: UPA00359 L21SP4_RS05900 51a7b0bd9134973fcfb0225d77f26acf 385 SUPERFAMILY SSF52540 64 191 4.75E-8 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS05900 51a7b0bd9134973fcfb0225d77f26acf 385 PANTHER PTHR30160 120 382 5.9E-61 T 22-04-2016 L21SP4_RS05900 51a7b0bd9134973fcfb0225d77f26acf 385 PANTHER PTHR30160 1 104 5.9E-61 T 22-04-2016 L21SP4_RS05900 51a7b0bd9134973fcfb0225d77f26acf 385 TIGRFAM TIGR00682 lpxK: tetraacyldisaccharide 4'-kinase 139 367 4.5E-37 T 22-04-2016 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130|UniPathway: UPA00359 L21SP4_RS05900 51a7b0bd9134973fcfb0225d77f26acf 385 PANTHER PTHR30160:SF13 120 382 5.9E-61 T 22-04-2016 L21SP4_RS05900 51a7b0bd9134973fcfb0225d77f26acf 385 PANTHER PTHR30160:SF13 1 104 5.9E-61 T 22-04-2016 L21SP4_RS00410 7090cbc1ec0e633392ccf658584755f8 788 SUPERFAMILY SSF48452 249 316 4.8E-5 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS00410 7090cbc1ec0e633392ccf658584755f8 788 SUPERFAMILY SSF48452 588 690 1.18E-8 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS00410 7090cbc1ec0e633392ccf658584755f8 788 Gene3D G3DSA:1.25.40.10 621 765 2.2E-16 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS00410 7090cbc1ec0e633392ccf658584755f8 788 Gene3D G3DSA:1.25.40.10 435 545 2.2E-16 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS00410 7090cbc1ec0e633392ccf658584755f8 788 SMART SM00028 512 545 62.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS00410 7090cbc1ec0e633392ccf658584755f8 788 SMART SM00028 362 395 210.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS00410 7090cbc1ec0e633392ccf658584755f8 788 SMART SM00028 436 469 440.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS00410 7090cbc1ec0e633392ccf658584755f8 788 SMART SM00028 37 70 230.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS00410 7090cbc1ec0e633392ccf658584755f8 788 SMART SM00028 658 691 53.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS00410 7090cbc1ec0e633392ccf658584755f8 788 SMART SM00028 325 358 400.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS00410 7090cbc1ec0e633392ccf658584755f8 788 SMART SM00028 621 654 84.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS00410 7090cbc1ec0e633392ccf658584755f8 788 Gene3D G3DSA:1.25.40.10 248 407 1.9E-15 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS00410 7090cbc1ec0e633392ccf658584755f8 788 Gene3D G3DSA:1.25.40.10 39 127 1.9E-15 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS00410 7090cbc1ec0e633392ccf658584755f8 788 Pfam PF13432 Tetratricopeptide repeat 339 387 0.0012 T 22-04-2016 L21SP4_RS00410 7090cbc1ec0e633392ccf658584755f8 788 Pfam PF13432 Tetratricopeptide repeat 625 685 1.0E-4 T 22-04-2016 L21SP4_RS00410 7090cbc1ec0e633392ccf658584755f8 788 Pfam PF13432 Tetratricopeptide repeat 480 545 0.0026 T 22-04-2016 L21SP4_RS00410 7090cbc1ec0e633392ccf658584755f8 788 SUPERFAMILY SSF48452 39 158 4.8E-5 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS00410 7090cbc1ec0e633392ccf658584755f8 788 SUPERFAMILY SSF48452 251 554 1.2E-13 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS09175 e4ee4e1053eedb76e8184995598a8ec9 381 Pfam PF00990 Diguanylate cyclase, GGDEF domain 212 364 5.2E-17 T 22-04-2016 IPR000160 GGDEF domain L21SP4_RS09175 e4ee4e1053eedb76e8184995598a8ec9 381 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 211 368 8.1E-17 T 22-04-2016 IPR000160 GGDEF domain L21SP4_RS09175 e4ee4e1053eedb76e8184995598a8ec9 381 SMART SM00267 199 371 2.0E-11 T 22-04-2016 IPR000160 GGDEF domain L21SP4_RS09175 e4ee4e1053eedb76e8184995598a8ec9 381 Gene3D G3DSA:3.30.70.270 214 377 1.5E-24 T 22-04-2016 L21SP4_RS09175 e4ee4e1053eedb76e8184995598a8ec9 381 SUPERFAMILY SSF55073 233 372 1.57E-21 T 22-04-2016 IPR029787 Nucleotide cyclase L21SP4_RS08155 b3ddec23604bdb8792dbe02b90228e6d 1053 PRINTS PR00344 Bacterial sensor protein C-terminal signature 842 856 1.0E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS08155 b3ddec23604bdb8792dbe02b90228e6d 1053 PRINTS PR00344 Bacterial sensor protein C-terminal signature 860 870 1.0E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS08155 b3ddec23604bdb8792dbe02b90228e6d 1053 PRINTS PR00344 Bacterial sensor protein C-terminal signature 897 910 1.0E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS08155 b3ddec23604bdb8792dbe02b90228e6d 1053 PRINTS PR00344 Bacterial sensor protein C-terminal signature 873 891 1.0E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS08155 b3ddec23604bdb8792dbe02b90228e6d 1053 SUPERFAMILY SSF55785 544 666 3.14E-13 T 22-04-2016 IPR000014 PAS domain L21SP4_RS08155 b3ddec23604bdb8792dbe02b90228e6d 1053 Pfam PF13426 PAS domain 445 546 9.9E-9 T 22-04-2016 IPR000014 PAS domain L21SP4_RS08155 b3ddec23604bdb8792dbe02b90228e6d 1053 Gene3D G3DSA:3.30.450.20 314 424 8.1E-31 T 22-04-2016 L21SP4_RS08155 b3ddec23604bdb8792dbe02b90228e6d 1053 Gene3D G3DSA:3.30.450.20 545 666 1.2E-12 T 22-04-2016 L21SP4_RS08155 b3ddec23604bdb8792dbe02b90228e6d 1053 Gene3D G3DSA:3.30.450.20 425 544 2.6E-19 T 22-04-2016 L21SP4_RS08155 b3ddec23604bdb8792dbe02b90228e6d 1053 Gene3D G3DSA:3.30.450.20 196 313 7.7E-22 T 22-04-2016 L21SP4_RS08155 b3ddec23604bdb8792dbe02b90228e6d 1053 SUPERFAMILY SSF55874 739 912 6.81E-39 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS08155 b3ddec23604bdb8792dbe02b90228e6d 1053 SMART SM00448 933 1046 2.7E-23 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 L21SP4_RS08155 b3ddec23604bdb8792dbe02b90228e6d 1053 Gene3D G3DSA:3.40.50.2300 933 1052 4.9E-31 T 22-04-2016 L21SP4_RS08155 b3ddec23604bdb8792dbe02b90228e6d 1053 SUPERFAMILY SSF52172 935 1052 1.99E-29 T 22-04-2016 IPR011006 CheY-like superfamily L21SP4_RS08155 b3ddec23604bdb8792dbe02b90228e6d 1053 SUPERFAMILY SSF55785 304 425 3.07E-29 T 22-04-2016 IPR000014 PAS domain L21SP4_RS08155 b3ddec23604bdb8792dbe02b90228e6d 1053 PANTHER PTHR24423 628 1051 1.0E-174 T 22-04-2016 L21SP4_RS08155 b3ddec23604bdb8792dbe02b90228e6d 1053 PANTHER PTHR24423 1 507 1.0E-174 T 22-04-2016 L21SP4_RS08155 b3ddec23604bdb8792dbe02b90228e6d 1053 Pfam PF00512 His Kinase A (phospho-acceptor) domain 684 747 1.6E-6 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS08155 b3ddec23604bdb8792dbe02b90228e6d 1053 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 791 911 4.1E-19 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS08155 b3ddec23604bdb8792dbe02b90228e6d 1053 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 440 554 1.4E-16 T 22-04-2016 IPR000014 PAS domain L21SP4_RS08155 b3ddec23604bdb8792dbe02b90228e6d 1053 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 315 433 3.0E-24 T 22-04-2016 IPR000014 PAS domain L21SP4_RS08155 b3ddec23604bdb8792dbe02b90228e6d 1053 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 195 314 3.5E-15 T 22-04-2016 IPR000014 PAS domain L21SP4_RS08155 b3ddec23604bdb8792dbe02b90228e6d 1053 SMART SM00091 198 264 1.4E-8 T 22-04-2016 IPR000014 PAS domain L21SP4_RS08155 b3ddec23604bdb8792dbe02b90228e6d 1053 SMART SM00091 435 502 5.9 T 22-04-2016 IPR000014 PAS domain L21SP4_RS08155 b3ddec23604bdb8792dbe02b90228e6d 1053 SMART SM00091 319 385 6.2E-14 T 22-04-2016 IPR000014 PAS domain L21SP4_RS08155 b3ddec23604bdb8792dbe02b90228e6d 1053 Gene3D G3DSA:3.30.565.10 723 911 3.2E-38 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS08155 b3ddec23604bdb8792dbe02b90228e6d 1053 SMART SM00086 390 427 5.8 T 22-04-2016 IPR001610 PAC motif L21SP4_RS08155 b3ddec23604bdb8792dbe02b90228e6d 1053 SMART SM00086 628 668 370.0 T 22-04-2016 IPR001610 PAC motif L21SP4_RS08155 b3ddec23604bdb8792dbe02b90228e6d 1053 SMART SM00086 507 547 2.6 T 22-04-2016 IPR001610 PAC motif L21SP4_RS08155 b3ddec23604bdb8792dbe02b90228e6d 1053 Pfam PF08448 PAS fold 567 669 5.4E-7 T 22-04-2016 IPR013656 PAS fold-4 L21SP4_RS08155 b3ddec23604bdb8792dbe02b90228e6d 1053 Pfam PF08448 PAS fold 204 309 7.5E-18 T 22-04-2016 IPR013656 PAS fold-4 L21SP4_RS08155 b3ddec23604bdb8792dbe02b90228e6d 1053 Pfam PF08448 PAS fold 325 429 8.4E-14 T 22-04-2016 IPR013656 PAS fold-4 L21SP4_RS08155 b3ddec23604bdb8792dbe02b90228e6d 1053 SMART SM00387 790 913 4.0E-26 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS08155 b3ddec23604bdb8792dbe02b90228e6d 1053 SUPERFAMILY SSF55785 209 315 2.93E-18 T 22-04-2016 IPR000014 PAS domain L21SP4_RS08155 b3ddec23604bdb8792dbe02b90228e6d 1053 PANTHER PTHR24423:SF458 628 1051 1.0E-174 T 22-04-2016 L21SP4_RS08155 b3ddec23604bdb8792dbe02b90228e6d 1053 PANTHER PTHR24423:SF458 1 507 1.0E-174 T 22-04-2016 L21SP4_RS08155 b3ddec23604bdb8792dbe02b90228e6d 1053 SUPERFAMILY SSF55785 447 556 2.09E-18 T 22-04-2016 IPR000014 PAS domain L21SP4_RS08155 b3ddec23604bdb8792dbe02b90228e6d 1053 Pfam PF00072 Response regulator receiver domain 935 1046 2.6E-21 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 L21SP4_RS08155 b3ddec23604bdb8792dbe02b90228e6d 1053 SMART SM00388 683 749 3.4E-6 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS08155 b3ddec23604bdb8792dbe02b90228e6d 1053 SUPERFAMILY SSF47384 671 746 1.12E-9 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS03515 360b67feddc5c195d7d201b2be0d12a3 93 Gene3D G3DSA:3.30.70.1120 1 92 2.7E-30 T 22-04-2016 IPR007546 Protein of unknown function DUF503 L21SP4_RS03515 360b67feddc5c195d7d201b2be0d12a3 93 Pfam PF04456 Protein of unknown function (DUF503) 3 89 2.6E-29 T 22-04-2016 IPR007546 Protein of unknown function DUF503 L21SP4_RS03515 360b67feddc5c195d7d201b2be0d12a3 93 PANTHER PTHR36441 2 92 3.8E-21 T 22-04-2016 L21SP4_RS03515 360b67feddc5c195d7d201b2be0d12a3 93 SUPERFAMILY SSF103007 1 91 3.66E-26 T 22-04-2016 IPR007546 Protein of unknown function DUF503 L21SP4_RS05140 b413db4d7ef31e4495c9e0c4262c779a 173 Pfam PF00881 Nitroreductase family 63 147 1.1E-13 T 22-04-2016 IPR029479 Nitroreductase L21SP4_RS05140 b413db4d7ef31e4495c9e0c4262c779a 173 Pfam PF00881 Nitroreductase family 8 61 2.3E-15 T 22-04-2016 IPR029479 Nitroreductase L21SP4_RS05140 b413db4d7ef31e4495c9e0c4262c779a 173 PANTHER PTHR23026 2 171 3.5E-41 T 22-04-2016 L21SP4_RS05140 b413db4d7ef31e4495c9e0c4262c779a 173 Gene3D G3DSA:3.40.109.10 2 167 1.7E-52 T 22-04-2016 IPR000415 Nitroreductase-like GO:0016491 L21SP4_RS05140 b413db4d7ef31e4495c9e0c4262c779a 173 SUPERFAMILY SSF55469 2 167 1.96E-51 T 22-04-2016 IPR000415 Nitroreductase-like GO:0016491 L21SP4_RS10935 adf9bfea06f57777b5c1428573af0c71 262 SUPERFAMILY SSF51366 11 257 9.18E-73 T 22-04-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 L21SP4_RS10935 adf9bfea06f57777b5c1428573af0c71 262 PANTHER PTHR22854 2 261 5.6E-88 T 22-04-2016 L21SP4_RS10935 adf9bfea06f57777b5c1428573af0c71 262 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 2 258 31.264 T 22-04-2016 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48|UniPathway: UPA00035 L21SP4_RS10935 adf9bfea06f57777b5c1428573af0c71 262 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 52 70 - T 22-04-2016 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48|UniPathway: UPA00035 L21SP4_RS10935 adf9bfea06f57777b5c1428573af0c71 262 Gene3D G3DSA:3.20.20.70 2 257 4.0E-92 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP4_RS10935 adf9bfea06f57777b5c1428573af0c71 262 Pfam PF00218 Indole-3-glycerol phosphate synthase 4 256 1.2E-73 T 22-04-2016 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48|UniPathway: UPA00035 L21SP4_RS10935 adf9bfea06f57777b5c1428573af0c71 262 PANTHER PTHR22854:SF2 2 261 5.6E-88 T 22-04-2016 L21SP4_RS00140 e2bb8ef48f15686a3ab9d58eb9e85def 146 SMART SM00116 79 127 5.3E-11 T 22-04-2016 IPR000644 CBS domain L21SP4_RS00140 e2bb8ef48f15686a3ab9d58eb9e85def 146 SMART SM00116 14 61 9.8E-5 T 22-04-2016 IPR000644 CBS domain L21SP4_RS00140 e2bb8ef48f15686a3ab9d58eb9e85def 146 Pfam PF00571 CBS domain 72 127 4.2E-15 T 22-04-2016 IPR000644 CBS domain L21SP4_RS00140 e2bb8ef48f15686a3ab9d58eb9e85def 146 Pfam PF00571 CBS domain 13 60 3.5E-9 T 22-04-2016 IPR000644 CBS domain L21SP4_RS00140 e2bb8ef48f15686a3ab9d58eb9e85def 146 SUPERFAMILY SSF54631 13 142 7.58E-35 T 22-04-2016 L21SP4_RS00140 e2bb8ef48f15686a3ab9d58eb9e85def 146 PANTHER PTHR11911 13 143 5.0E-32 T 22-04-2016 L21SP4_RS00140 e2bb8ef48f15686a3ab9d58eb9e85def 146 Gene3D G3DSA:3.10.580.10 13 128 4.9E-34 T 22-04-2016 L21SP4_RS00140 e2bb8ef48f15686a3ab9d58eb9e85def 146 PANTHER PTHR11911:SF68 13 143 5.0E-32 T 22-04-2016 L21SP4_RS01880 78d5d2ee1b5374e9f4ceaa76834fa68a 166 SUPERFAMILY SSF52833 22 165 2.46E-48 T 22-04-2016 IPR012336 Thioredoxin-like fold L21SP4_RS01880 78d5d2ee1b5374e9f4ceaa76834fa68a 166 PIRSF PIRSF000216 6 166 1.0E-50 T 22-04-2016 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 L21SP4_RS01880 78d5d2ee1b5374e9f4ceaa76834fa68a 166 PANTHER PTHR10371 16 164 9.0E-55 T 22-04-2016 L21SP4_RS01880 78d5d2ee1b5374e9f4ceaa76834fa68a 166 Gene3D G3DSA:3.40.30.10 84 162 1.0E-13 T 22-04-2016 IPR012336 Thioredoxin-like fold L21SP4_RS01880 78d5d2ee1b5374e9f4ceaa76834fa68a 166 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 28 163 1.8E-46 T 22-04-2016 L21SP4_RS06065 75175e24aab92d63b95e01b7374a19eb 702 Gene3D G3DSA:1.50.10.10 87 261 3.3E-6 T 22-04-2016 IPR012341 Six-hairpin glycosidase GO:0003824 L21SP4_RS06065 75175e24aab92d63b95e01b7374a19eb 702 SUPERFAMILY SSF48208 76 370 7.91E-19 T 22-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP4_RS06065 75175e24aab92d63b95e01b7374a19eb 702 PANTHER PTHR31151 88 491 2.9E-38 T 22-04-2016 L21SP4_RS06065 75175e24aab92d63b95e01b7374a19eb 702 PANTHER PTHR31151 516 600 2.9E-38 T 22-04-2016 L21SP4_RS06065 75175e24aab92d63b95e01b7374a19eb 702 Pfam PF07944 Beta-L-arabinofuranosidase, GH127 50 574 3.1E-50 T 22-04-2016 IPR012878 Beta-L-arabinofuranosidase, GH127 KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18 L21SP4_RS00185 e6654704fb7176f49f7bebd6a86146f4 305 Pfam PF02445 Quinolinate synthetase A protein 6 299 4.4E-116 T 22-04-2016 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342|UniPathway: UPA00253 L21SP4_RS00185 e6654704fb7176f49f7bebd6a86146f4 305 PANTHER PTHR30573 6 299 2.2E-140 T 22-04-2016 L21SP4_RS00185 e6654704fb7176f49f7bebd6a86146f4 305 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 2 299 8.2E-104 T 22-04-2016 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342|UniPathway: UPA00253 L21SP4_RS00185 e6654704fb7176f49f7bebd6a86146f4 305 SUPERFAMILY SSF142754 4 299 1.7E-114 T 22-04-2016 L21SP4_RS00185 e6654704fb7176f49f7bebd6a86146f4 305 Hamap MF_00568 Quinolinate synthase A [nadA]. 2 300 42.697 T 22-04-2016 IPR023066 Quinolinate synthase A, type 2 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342|UniPathway: UPA00253 L21SP4_RS09765 7a1bb71371616ff8a46d6de856aeff11 344 PANTHER PTHR30294 149 344 2.8E-30 T 22-04-2016 L21SP4_RS09765 7a1bb71371616ff8a46d6de856aeff11 344 Pfam PF12698 ABC-2 family transporter protein 1 338 3.2E-27 T 22-04-2016 L21SP4_RS00535 8c074209f1606fd1d80d5c3007a40fc2 135 PANTHER PTHR34039:SF1 5 129 2.5E-31 T 22-04-2016 L21SP4_RS00535 8c074209f1606fd1d80d5c3007a40fc2 135 Pfam PF02021 Uncharacterised protein family UPF0102 16 107 2.2E-26 T 22-04-2016 IPR003509 Uncharacterised protein family UPF0102 L21SP4_RS00535 8c074209f1606fd1d80d5c3007a40fc2 135 PANTHER PTHR34039 5 129 2.5E-31 T 22-04-2016 L21SP4_RS00535 8c074209f1606fd1d80d5c3007a40fc2 135 Gene3D G3DSA:3.40.1350.10 15 126 9.3E-33 T 22-04-2016 IPR011856 tRNA endonuclease-like domain GO:0003676|GO:0004518 L21SP4_RS00535 8c074209f1606fd1d80d5c3007a40fc2 135 SUPERFAMILY SSF52980 11 119 6.33E-23 T 22-04-2016 IPR011335 Restriction endonuclease type II-like L21SP4_RS00535 8c074209f1606fd1d80d5c3007a40fc2 135 Hamap MF_00048 UPF0102 protein YraN [yraN]. 9 120 20.741 T 22-04-2016 IPR003509 Uncharacterised protein family UPF0102 L21SP4_RS02155 1e2d922a514d2a15cbdbb4ae80feae7a 288 PANTHER PTHR23342 1 288 9.7E-96 T 22-04-2016 L21SP4_RS02155 1e2d922a514d2a15cbdbb4ae80feae7a 288 PIRSF PIRSF000728 9 288 1.1E-90 T 22-04-2016 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 L21SP4_RS02155 1e2d922a514d2a15cbdbb4ae80feae7a 288 SUPERFAMILY SSF53633 2 288 2.36E-78 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 L21SP4_RS02155 1e2d922a514d2a15cbdbb4ae80feae7a 288 Pfam PF00696 Amino acid kinase family 25 265 7.5E-44 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 L21SP4_RS02155 1e2d922a514d2a15cbdbb4ae80feae7a 288 Hamap MF_00082_B Acetylglutamate kinase [argB]. 22 288 30.994 T 22-04-2016 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 L21SP4_RS02155 1e2d922a514d2a15cbdbb4ae80feae7a 288 TIGRFAM TIGR00761 argB: acetylglutamate kinase 26 263 3.2E-67 T 22-04-2016 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 L21SP4_RS02155 1e2d922a514d2a15cbdbb4ae80feae7a 288 PRINTS PR00474 Glutamate 5-kinase family signature 238 258 1.9E-7 T 22-04-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 L21SP4_RS02155 1e2d922a514d2a15cbdbb4ae80feae7a 288 PRINTS PR00474 Glutamate 5-kinase family signature 55 69 1.9E-7 T 22-04-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 L21SP4_RS02155 1e2d922a514d2a15cbdbb4ae80feae7a 288 PRINTS PR00474 Glutamate 5-kinase family signature 185 212 1.9E-7 T 22-04-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 L21SP4_RS02155 1e2d922a514d2a15cbdbb4ae80feae7a 288 Gene3D G3DSA:3.40.1160.10 22 287 2.4E-86 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 L21SP4_RS12165 1e7b549706e79def82e39b5924c36581 424 Gene3D G3DSA:1.10.287.40 1 104 1.6E-26 T 22-04-2016 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|UniPathway: UPA00906 L21SP4_RS12165 1e7b549706e79def82e39b5924c36581 424 PRINTS PR00981 Seryl-tRNA synthetase signature 314 327 8.9E-30 T 22-04-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 L21SP4_RS12165 1e7b549706e79def82e39b5924c36581 424 PRINTS PR00981 Seryl-tRNA synthetase signature 349 365 8.9E-30 T 22-04-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 L21SP4_RS12165 1e7b549706e79def82e39b5924c36581 424 PRINTS PR00981 Seryl-tRNA synthetase signature 274 287 8.9E-30 T 22-04-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 L21SP4_RS12165 1e7b549706e79def82e39b5924c36581 424 PRINTS PR00981 Seryl-tRNA synthetase signature 262 274 8.9E-30 T 22-04-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 L21SP4_RS12165 1e7b549706e79def82e39b5924c36581 424 PRINTS PR00981 Seryl-tRNA synthetase signature 331 347 8.9E-30 T 22-04-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 L21SP4_RS12165 1e7b549706e79def82e39b5924c36581 424 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 414 5.7E-153 T 22-04-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 L21SP4_RS12165 1e7b549706e79def82e39b5924c36581 424 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 221 397 1.0E-33 T 22-04-2016 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 L21SP4_RS12165 1e7b549706e79def82e39b5924c36581 424 SUPERFAMILY SSF46589 1 112 1.67E-29 T 22-04-2016 IPR010978 tRNA-binding arm GO:0000166 Reactome: REACT_71 L21SP4_RS12165 1e7b549706e79def82e39b5924c36581 424 PIRSF PIRSF001529 1 423 1.3E-164 T 22-04-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 L21SP4_RS12165 1e7b549706e79def82e39b5924c36581 424 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 419 40.039 T 22-04-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 L21SP4_RS12165 1e7b549706e79def82e39b5924c36581 424 Gene3D G3DSA:3.30.930.10 105 418 6.8E-133 T 22-04-2016 L21SP4_RS12165 1e7b549706e79def82e39b5924c36581 424 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 107 1.9E-29 T 22-04-2016 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|UniPathway: UPA00906 L21SP4_RS12165 1e7b549706e79def82e39b5924c36581 424 SUPERFAMILY SSF55681 116 415 4.23E-99 T 22-04-2016 L21SP4_RS12165 1e7b549706e79def82e39b5924c36581 424 PANTHER PTHR11778 1 422 9.5E-200 T 22-04-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 L21SP4_RS05670 142c7e34a1b9b576efef77d96b64d76b 576 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 7 559 4.6E-227 T 22-04-2016 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 L21SP4_RS05670 142c7e34a1b9b576efef77d96b64d76b 576 SUPERFAMILY SSF52467 159 362 6.85E-57 T 22-04-2016 IPR029035 DHS-like NAD/FAD-binding domain L21SP4_RS05670 142c7e34a1b9b576efef77d96b64d76b 576 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 7 175 1.4E-58 T 22-04-2016 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 L21SP4_RS05670 142c7e34a1b9b576efef77d96b64d76b 576 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 388 536 5.7E-48 T 22-04-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 L21SP4_RS05670 142c7e34a1b9b576efef77d96b64d76b 576 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 425 444 - T 22-04-2016 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 L21SP4_RS05670 142c7e34a1b9b576efef77d96b64d76b 576 Gene3D G3DSA:3.40.50.970 361 565 1.9E-73 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold L21SP4_RS05670 142c7e34a1b9b576efef77d96b64d76b 576 Gene3D G3DSA:3.40.50.1220 191 360 7.7E-62 T 22-04-2016 IPR029035 DHS-like NAD/FAD-binding domain L21SP4_RS05670 142c7e34a1b9b576efef77d96b64d76b 576 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 198 333 3.1E-46 T 22-04-2016 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 L21SP4_RS05670 142c7e34a1b9b576efef77d96b64d76b 576 SUPERFAMILY SSF52518 364 564 1.04E-67 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold L21SP4_RS05670 142c7e34a1b9b576efef77d96b64d76b 576 Gene3D G3DSA:3.40.50.970 6 182 2.9E-71 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold L21SP4_RS05670 142c7e34a1b9b576efef77d96b64d76b 576 PANTHER PTHR18968:SF116 1 566 5.0E-283 T 22-04-2016 L21SP4_RS05670 142c7e34a1b9b576efef77d96b64d76b 576 SUPERFAMILY SSF52518 4 189 1.5E-60 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold L21SP4_RS05670 142c7e34a1b9b576efef77d96b64d76b 576 PANTHER PTHR18968 1 566 5.0E-283 T 22-04-2016 L21SP4_RS00280 f17c347dd8c4dfbb3ce19d4daf2f9157 248 PANTHER PTHR30027:SF3 10 248 1.3E-29 T 22-04-2016 L21SP4_RS00280 f17c347dd8c4dfbb3ce19d4daf2f9157 248 PIRSF PIRSF015601 1 248 2.2E-37 T 22-04-2016 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 L21SP4_RS00280 f17c347dd8c4dfbb3ce19d4daf2f9157 248 Gene3D G3DSA:3.40.1280.10 1 245 3.0E-56 T 22-04-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal L21SP4_RS00280 f17c347dd8c4dfbb3ce19d4daf2f9157 248 SUPERFAMILY SSF75217 72 241 3.97E-30 T 22-04-2016 IPR029028 Alpha/beta knot methyltransferases L21SP4_RS00280 f17c347dd8c4dfbb3ce19d4daf2f9157 248 Pfam PF04452 RNA methyltransferase 18 241 7.9E-38 T 22-04-2016 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 L21SP4_RS00280 f17c347dd8c4dfbb3ce19d4daf2f9157 248 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 10 241 8.3E-20 T 22-04-2016 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 L21SP4_RS00280 f17c347dd8c4dfbb3ce19d4daf2f9157 248 PANTHER PTHR30027 10 248 1.3E-29 T 22-04-2016 L21SP4_RS09625 925fca7ed9acc761cb8ce7acf4541ff8 157 Gene3D G3DSA:2.40.30.70 3 143 7.9E-53 T 22-04-2016 IPR023370 TsaA-like domain L21SP4_RS09625 925fca7ed9acc761cb8ce7acf4541ff8 157 SUPERFAMILY SSF118196 3 145 3.92E-52 T 22-04-2016 IPR023370 TsaA-like domain L21SP4_RS09625 925fca7ed9acc761cb8ce7acf4541ff8 157 TIGRFAM TIGR00104 tRNA_TsaA: tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase TsaA 3 134 8.2E-39 T 22-04-2016 IPR023370 TsaA-like domain L21SP4_RS09625 925fca7ed9acc761cb8ce7acf4541ff8 157 PANTHER PTHR12818 3 141 6.2E-53 T 22-04-2016 L21SP4_RS09625 925fca7ed9acc761cb8ce7acf4541ff8 157 Pfam PF01980 Uncharacterised protein family UPF0066 18 130 1.3E-36 T 22-04-2016 IPR023370 TsaA-like domain L21SP4_RS03015 6ba195c2c021aa50512994c52b11c951 401 Pfam PF00953 Glycosyl transferase family 4 113 262 1.1E-30 T 22-04-2016 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 L21SP4_RS03015 6ba195c2c021aa50512994c52b11c951 401 PANTHER PTHR22926 23 395 3.0E-67 T 22-04-2016 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 L21SP4_RS03015 6ba195c2c021aa50512994c52b11c951 401 PANTHER PTHR22926:SF3 23 395 3.0E-67 T 22-04-2016 L21SP4_RS02000 8b331a1af7b0717c3e6f8742dc329c50 481 Pfam PF13347 MFS/sugar transport protein 29 460 4.0E-78 T 22-04-2016 L21SP4_RS02000 8b331a1af7b0717c3e6f8742dc329c50 481 ProSitePatterns PS00872 Sodium:galactoside symporter family signature. 78 103 - T 22-04-2016 IPR018043 Sodium:galactoside symporter, conserved site GO:0005215|GO:0006814|GO:0016020 L21SP4_RS02000 8b331a1af7b0717c3e6f8742dc329c50 481 PANTHER PTHR11328 27 480 4.3E-71 T 22-04-2016 L21SP4_RS02000 8b331a1af7b0717c3e6f8742dc329c50 481 Gene3D G3DSA:1.20.1250.20 256 462 1.5E-13 T 22-04-2016 L21SP4_RS02000 8b331a1af7b0717c3e6f8742dc329c50 481 Gene3D G3DSA:1.20.1250.20 30 224 5.2E-14 T 22-04-2016 L21SP4_RS02000 8b331a1af7b0717c3e6f8742dc329c50 481 PANTHER PTHR11328:SF24 27 480 4.3E-71 T 22-04-2016 L21SP4_RS02000 8b331a1af7b0717c3e6f8742dc329c50 481 SUPERFAMILY SSF103473 29 462 1.57E-32 T 22-04-2016 IPR020846 Major facilitator superfamily domain L21SP4_RS01950 38d61889fcc169f3d9e3219b7922ad35 519 SUPERFAMILY SSF53649 31 492 1.45E-105 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS01950 38d61889fcc169f3d9e3219b7922ad35 519 Pfam PF00884 Sulfatase 33 379 4.2E-42 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS01950 38d61889fcc169f3d9e3219b7922ad35 519 PANTHER PTHR10342:SF207 4 515 1.7E-140 T 22-04-2016 L21SP4_RS01950 38d61889fcc169f3d9e3219b7922ad35 519 Gene3D G3DSA:3.40.720.10 30 398 1.4E-81 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS01950 38d61889fcc169f3d9e3219b7922ad35 519 PANTHER PTHR10342 4 515 1.7E-140 T 22-04-2016 L21SP4_RS01950 38d61889fcc169f3d9e3219b7922ad35 519 Gene3D G3DSA:3.30.1120.10 413 496 4.9E-11 T 22-04-2016 L21SP4_RS01195 aeb8a17629bca758180207d2cc489872 351 Pfam PF01263 Aldose 1-epimerase 15 344 4.7E-91 T 22-04-2016 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 L21SP4_RS01195 aeb8a17629bca758180207d2cc489872 351 PANTHER PTHR10091 1 348 4.5E-164 T 22-04-2016 L21SP4_RS01195 aeb8a17629bca758180207d2cc489872 351 PANTHER PTHR10091:SF0 1 348 4.5E-164 T 22-04-2016 L21SP4_RS01195 aeb8a17629bca758180207d2cc489872 351 Gene3D G3DSA:2.70.98.10 5 346 8.5E-134 T 22-04-2016 IPR014718 Glycoside hydrolase-type carbohydrate-binding, subgroup GO:0003824|GO:0005975|GO:0030246 L21SP4_RS01195 aeb8a17629bca758180207d2cc489872 351 SUPERFAMILY SSF74650 3 345 1.51E-119 T 22-04-2016 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 L21SP4_RS01195 aeb8a17629bca758180207d2cc489872 351 PIRSF PIRSF005096 2 348 3.0E-130 T 22-04-2016 IPR015443 Aldose 1-epimerase GO:0016853|GO:0019318 KEGG: 00010+5.1.3.3|KEGG: 00052+5.1.3.3|MetaCyc: PWY-6317|UniPathway: UPA00242 L21SP4_RS05975 09718766159105a59e885a703e4eb251 590 SUPERFAMILY SSF48208 269 438 3.4E-26 T 22-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP4_RS05975 09718766159105a59e885a703e4eb251 590 SUPERFAMILY SSF48208 124 237 3.4E-26 T 22-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP4_RS05975 09718766159105a59e885a703e4eb251 590 SUPERFAMILY SSF48208 470 540 3.4E-26 T 22-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP4_RS05975 09718766159105a59e885a703e4eb251 590 Gene3D G3DSA:2.60.40.10 75 123 6.4E-6 T 22-04-2016 IPR013783 Immunoglobulin-like fold L21SP4_RS05975 09718766159105a59e885a703e4eb251 590 Gene3D G3DSA:2.60.40.10 3 39 6.4E-6 T 22-04-2016 IPR013783 Immunoglobulin-like fold L21SP4_RS05975 09718766159105a59e885a703e4eb251 590 Gene3D G3DSA:1.50.10.10 132 533 3.3E-20 T 22-04-2016 IPR012341 Six-hairpin glycosidase GO:0003824 L21SP4_RS05975 09718766159105a59e885a703e4eb251 590 Pfam PF00759 Glycosyl hydrolase family 9 133 532 2.0E-12 T 22-04-2016 IPR001701 Glycoside hydrolase family 9 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 L21SP4_RS05950 7c76a7d9e2a26fdd33c0b73b6665acff 303 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 242 284 - T 22-04-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 L21SP4_RS05950 7c76a7d9e2a26fdd33c0b73b6665acff 303 SUPERFAMILY SSF51215 31 176 2.35E-12 T 22-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 L21SP4_RS05950 7c76a7d9e2a26fdd33c0b73b6665acff 303 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 257 272 2.2E-8 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 L21SP4_RS05950 7c76a7d9e2a26fdd33c0b73b6665acff 303 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 272 288 2.2E-8 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 L21SP4_RS05950 7c76a7d9e2a26fdd33c0b73b6665acff 303 Gene3D G3DSA:1.10.10.60 242 290 9.5E-18 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS05950 7c76a7d9e2a26fdd33c0b73b6665acff 303 Pfam PF07883 Cupin domain 48 93 1.0E-7 T 22-04-2016 IPR013096 Cupin 2, conserved barrel L21SP4_RS05950 7c76a7d9e2a26fdd33c0b73b6665acff 303 Pfam PF12833 Helix-turn-helix domain 214 289 6.5E-18 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP4_RS05950 7c76a7d9e2a26fdd33c0b73b6665acff 303 PANTHER PTHR11019 19 296 1.2E-30 T 22-04-2016 L21SP4_RS05950 7c76a7d9e2a26fdd33c0b73b6665acff 303 SMART SM00342 205 288 2.8E-21 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP4_RS05950 7c76a7d9e2a26fdd33c0b73b6665acff 303 SUPERFAMILY SSF46689 241 291 3.81E-13 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS05950 7c76a7d9e2a26fdd33c0b73b6665acff 303 Gene3D G3DSA:2.60.120.280 49 175 1.2E-14 T 22-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 L21SP4_RS05950 7c76a7d9e2a26fdd33c0b73b6665acff 303 Gene3D G3DSA:1.10.10.60 189 241 1.9E-9 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS05480 a540a4c0570ec2d25534c53f1f0ff4c3 446 Pfam PF01225 Mur ligase family, catalytic domain 20 113 8.9E-16 T 22-04-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 L21SP4_RS05480 a540a4c0570ec2d25534c53f1f0ff4c3 446 PANTHER PTHR23135 13 430 8.0E-113 T 22-04-2016 L21SP4_RS05480 a540a4c0570ec2d25534c53f1f0ff4c3 446 SUPERFAMILY SSF51984 20 107 3.4E-19 T 22-04-2016 L21SP4_RS05480 a540a4c0570ec2d25534c53f1f0ff4c3 446 SUPERFAMILY SSF53623 106 289 7.06E-41 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 L21SP4_RS05480 a540a4c0570ec2d25534c53f1f0ff4c3 446 Pfam PF02875 Mur ligase family, glutamate ligase domain 295 376 2.4E-16 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 L21SP4_RS05480 a540a4c0570ec2d25534c53f1f0ff4c3 446 Gene3D G3DSA:3.40.50.720 20 107 5.4E-24 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS05480 a540a4c0570ec2d25534c53f1f0ff4c3 446 Gene3D G3DSA:3.90.190.20 295 434 7.1E-40 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 L21SP4_RS05480 a540a4c0570ec2d25534c53f1f0ff4c3 446 SUPERFAMILY SSF53244 294 433 2.38E-35 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 L21SP4_RS05480 a540a4c0570ec2d25534c53f1f0ff4c3 446 Gene3D G3DSA:3.40.1190.10 257 290 9.7E-8 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 L21SP4_RS05480 a540a4c0570ec2d25534c53f1f0ff4c3 446 Gene3D G3DSA:3.40.1190.10 109 239 2.9E-34 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 L21SP4_RS05480 a540a4c0570ec2d25534c53f1f0ff4c3 446 PANTHER PTHR23135:SF5 13 430 8.0E-113 T 22-04-2016 L21SP4_RS05480 a540a4c0570ec2d25534c53f1f0ff4c3 446 Pfam PF08245 Mur ligase middle domain 125 230 4.7E-12 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 L21SP4_RS09155 519193c590abe922e57d62a2f02211b7 256 Pfam PF11984 Protein of unknown function (DUF3485) 11 247 1.2E-15 T 22-04-2016 IPR014263 Methanolan biosynthesis EpsI L21SP4_RS02750 06abda5c22584e625edb77537f9d7b64 117 PANTHER PTHR34182 5 77 1.7E-15 T 22-04-2016 L21SP4_RS02750 06abda5c22584e625edb77537f9d7b64 117 PRINTS PR01651 Protein-export SecG membrane protein signature 26 40 8.4E-11 T 22-04-2016 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 L21SP4_RS02750 06abda5c22584e625edb77537f9d7b64 117 PRINTS PR01651 Protein-export SecG membrane protein signature 56 78 8.4E-11 T 22-04-2016 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 L21SP4_RS02750 06abda5c22584e625edb77537f9d7b64 117 PRINTS PR01651 Protein-export SecG membrane protein signature 6 26 8.4E-11 T 22-04-2016 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 L21SP4_RS02750 06abda5c22584e625edb77537f9d7b64 117 Pfam PF03840 Preprotein translocase SecG subunit 7 75 7.8E-19 T 22-04-2016 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 L21SP4_RS02750 06abda5c22584e625edb77537f9d7b64 117 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 6 75 2.2E-19 T 22-04-2016 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 L21SP4_RS03765 72ffed4c9ab8a851a8be93b0b9a52575 512 Gene3D G3DSA:3.40.720.10 1 411 1.1E-102 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS03765 72ffed4c9ab8a851a8be93b0b9a52575 512 PANTHER PTHR10342 124 243 7.1E-128 T 22-04-2016 L21SP4_RS03765 72ffed4c9ab8a851a8be93b0b9a52575 512 PANTHER PTHR10342 270 491 7.1E-128 T 22-04-2016 L21SP4_RS03765 72ffed4c9ab8a851a8be93b0b9a52575 512 PANTHER PTHR10342 1 104 7.1E-128 T 22-04-2016 L21SP4_RS03765 72ffed4c9ab8a851a8be93b0b9a52575 512 Gene3D G3DSA:3.30.1120.10 417 497 6.3E-16 T 22-04-2016 L21SP4_RS03765 72ffed4c9ab8a851a8be93b0b9a52575 512 Pfam PF00884 Sulfatase 1 385 2.2E-65 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS03765 72ffed4c9ab8a851a8be93b0b9a52575 512 PANTHER PTHR10342:SF199 124 243 7.1E-128 T 22-04-2016 L21SP4_RS03765 72ffed4c9ab8a851a8be93b0b9a52575 512 PANTHER PTHR10342:SF199 270 491 7.1E-128 T 22-04-2016 L21SP4_RS03765 72ffed4c9ab8a851a8be93b0b9a52575 512 PANTHER PTHR10342:SF199 1 104 7.1E-128 T 22-04-2016 L21SP4_RS03765 72ffed4c9ab8a851a8be93b0b9a52575 512 ProSitePatterns PS00149 Sulfatases signature 2. 93 103 - T 22-04-2016 IPR024607 Sulfatase, conserved site L21SP4_RS03765 72ffed4c9ab8a851a8be93b0b9a52575 512 SUPERFAMILY SSF53649 1 105 5.09E-121 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS03765 72ffed4c9ab8a851a8be93b0b9a52575 512 SUPERFAMILY SSF53649 132 493 5.09E-121 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS07340 e436daf228a3285fd58a775d5b71b30c 157 Pfam PF05991 YacP-like NYN domain 5 145 1.6E-24 T 22-04-2016 IPR010298 Protein of unknown function DUF901 L21SP4_RS07340 e436daf228a3285fd58a775d5b71b30c 157 PANTHER PTHR34547 1 135 4.5E-13 T 22-04-2016 L21SP4_RS10975 5928b6f655259a48f544cb0aa379f323 250 Pfam PF11932 Protein of unknown function (DUF3450) 4 242 5.4E-27 T 22-04-2016 IPR016866 Uncharacterised conserved protein UCP028069 L21SP4_RS09115 ea7d9271c97965c07947595388a95b21 264 Pfam PF01966 HD domain 37 154 3.8E-8 T 22-04-2016 IPR006674 HD domain L21SP4_RS09115 ea7d9271c97965c07947595388a95b21 264 SUPERFAMILY SSF109604 37 159 1.46E-15 T 22-04-2016 L21SP4_RS09115 ea7d9271c97965c07947595388a95b21 264 Gene3D G3DSA:1.10.3210.10 37 156 1.2E-11 T 22-04-2016 IPR006674 HD domain L21SP4_RS02665 ff648e2644f694fa4cee16a9656222cc 181 SUPERFAMILY SSF52540 10 171 9.11E-27 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS02665 ff648e2644f694fa4cee16a9656222cc 181 ProSitePatterns PS01128 Shikimate kinase signature. 65 90 - T 22-04-2016 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163|UniPathway: UPA00053 L21SP4_RS02665 ff648e2644f694fa4cee16a9656222cc 181 Hamap MF_00109 Shikimate kinase [aroK]. 9 173 26.514 T 22-04-2016 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163|UniPathway: UPA00053 L21SP4_RS02665 ff648e2644f694fa4cee16a9656222cc 181 PANTHER PTHR21087 8 174 6.8E-49 T 22-04-2016 L21SP4_RS02665 ff648e2644f694fa4cee16a9656222cc 181 PANTHER PTHR21087:SF0 8 174 6.8E-49 T 22-04-2016 L21SP4_RS02665 ff648e2644f694fa4cee16a9656222cc 181 Pfam PF01202 Shikimate kinase 18 171 3.7E-43 T 22-04-2016 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163|UniPathway: UPA00053 L21SP4_RS02665 ff648e2644f694fa4cee16a9656222cc 181 PRINTS PR01100 Shikimate kinase family signature 64 72 1.4E-22 T 22-04-2016 L21SP4_RS02665 ff648e2644f694fa4cee16a9656222cc 181 PRINTS PR01100 Shikimate kinase family signature 103 120 1.4E-22 T 22-04-2016 L21SP4_RS02665 ff648e2644f694fa4cee16a9656222cc 181 PRINTS PR01100 Shikimate kinase family signature 12 27 1.4E-22 T 22-04-2016 L21SP4_RS02665 ff648e2644f694fa4cee16a9656222cc 181 PRINTS PR01100 Shikimate kinase family signature 36 49 1.4E-22 T 22-04-2016 L21SP4_RS02665 ff648e2644f694fa4cee16a9656222cc 181 PRINTS PR01100 Shikimate kinase family signature 82 91 1.4E-22 T 22-04-2016 L21SP4_RS02665 ff648e2644f694fa4cee16a9656222cc 181 Gene3D G3DSA:3.40.50.300 9 174 1.0E-50 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS06115 7de6d37d84318b9f6689d868d21ca30f 718 SUPERFAMILY SSF48452 570 675 1.92E-10 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS06115 7de6d37d84318b9f6689d868d21ca30f 718 Gene3D G3DSA:1.25.40.10 571 675 5.7E-8 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS06115 7de6d37d84318b9f6689d868d21ca30f 718 SUPERFAMILY SSF48208 224 399 3.32E-11 T 22-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP4_RS06670 d80013d07496a0c94c8c8eb94829d25c 995 PANTHER PTHR33307 1 111 1.4E-197 T 22-04-2016 L21SP4_RS06670 d80013d07496a0c94c8c8eb94829d25c 995 PANTHER PTHR33307 286 971 1.4E-197 T 22-04-2016 L21SP4_RS06670 d80013d07496a0c94c8c8eb94829d25c 995 PANTHER PTHR33307:SF5 286 971 1.4E-197 T 22-04-2016 L21SP4_RS06670 d80013d07496a0c94c8c8eb94829d25c 995 Gene3D G3DSA:2.60.120.260 469 579 3.1E-7 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS06670 d80013d07496a0c94c8c8eb94829d25c 995 Pfam PF08531 Alpha-L-rhamnosidase N-terminal domain 306 440 1.2E-33 T 22-04-2016 IPR013737 Bacterial alpha-L-rhamnosidase N-terminal L21SP4_RS06670 d80013d07496a0c94c8c8eb94829d25c 995 PANTHER PTHR33307:SF5 1 111 1.4E-197 T 22-04-2016 L21SP4_RS06670 d80013d07496a0c94c8c8eb94829d25c 995 Pfam PF05592 Bacterial alpha-L-rhamnosidase 477 968 3.0E-141 T 22-04-2016 IPR008902 Bacterial alpha-L-rhamnosidase L21SP4_RS06670 d80013d07496a0c94c8c8eb94829d25c 995 PIRSF PIRSF010631 1 988 2.9E-204 T 22-04-2016 IPR016007 Alpha-L-rhamnosidase L21SP4_RS06670 d80013d07496a0c94c8c8eb94829d25c 995 SUPERFAMILY SSF48208 578 968 1.26E-44 T 22-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP4_RS02090 35132a110b464914c1df08312cf041c3 332 SUPERFAMILY SSF56784 25 45 2.1E-14 T 22-04-2016 IPR023214 HAD-like domain L21SP4_RS02090 35132a110b464914c1df08312cf041c3 332 SUPERFAMILY SSF56784 177 316 2.1E-14 T 22-04-2016 IPR023214 HAD-like domain L21SP4_RS02090 35132a110b464914c1df08312cf041c3 332 Pfam PF13242 HAD-hyrolase-like 251 292 1.1E-4 T 22-04-2016 L21SP4_RS02090 35132a110b464914c1df08312cf041c3 332 Gene3D G3DSA:3.40.50.1000 177 317 2.5E-12 T 22-04-2016 IPR023214 HAD-like domain L21SP4_RS02090 35132a110b464914c1df08312cf041c3 332 Gene3D G3DSA:3.40.50.1000 25 47 2.5E-12 T 22-04-2016 IPR023214 HAD-like domain L21SP4_RS02845 d7972e67add1435df165fe7f173081b9 204 TIGRFAM TIGR01940 nqrE: NADH:ubiquinone oxidoreductase, Na(+)-translocating, E subunit 2 203 9.7E-92 T 22-04-2016 IPR010967 Na(+)-translocating NADH-quinone reductase subunit E GO:0009276|GO:0016021|GO:0016655|GO:0022904|GO:0055114 L21SP4_RS02845 d7972e67add1435df165fe7f173081b9 204 Hamap MF_00429 Na(+)-translocating NADH-quinone reductase subunit E [nqrE]. 1 204 27.437 T 22-04-2016 IPR010967 Na(+)-translocating NADH-quinone reductase subunit E GO:0009276|GO:0016021|GO:0016655|GO:0022904|GO:0055114 L21SP4_RS02845 d7972e67add1435df165fe7f173081b9 204 PANTHER PTHR30335 1 204 4.1E-113 T 22-04-2016 L21SP4_RS02845 d7972e67add1435df165fe7f173081b9 204 PIRSF PIRSF006102 1 204 3.5E-59 T 22-04-2016 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 L21SP4_RS02845 d7972e67add1435df165fe7f173081b9 204 Pfam PF02508 Rnf-Nqr subunit, membrane protein 6 202 1.2E-57 T 22-04-2016 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 L21SP4_RS02845 d7972e67add1435df165fe7f173081b9 204 PANTHER PTHR30335:SF1 1 204 4.1E-113 T 22-04-2016 IPR010967 Na(+)-translocating NADH-quinone reductase subunit E GO:0009276|GO:0016021|GO:0016655|GO:0022904|GO:0055114 L21SP4_RS01095 9a95c836b86754daa96773ab1469f1d5 277 PANTHER PTHR12725 29 273 5.1E-23 T 22-04-2016 L21SP4_RS01095 9a95c836b86754daa96773ab1469f1d5 277 Pfam PF13419 Haloacid dehalogenase-like hydrolase 114 234 2.0E-7 T 22-04-2016 IPR023214 HAD-like domain L21SP4_RS01095 9a95c836b86754daa96773ab1469f1d5 277 SUPERFAMILY SSF56784 45 271 9.57E-26 T 22-04-2016 IPR023214 HAD-like domain L21SP4_RS01095 9a95c836b86754daa96773ab1469f1d5 277 PANTHER PTHR12725:SF57 29 273 5.1E-23 T 22-04-2016 L21SP4_RS01095 9a95c836b86754daa96773ab1469f1d5 277 Gene3D G3DSA:3.40.50.1000 128 270 2.2E-21 T 22-04-2016 IPR023214 HAD-like domain L21SP4_RS01095 9a95c836b86754daa96773ab1469f1d5 277 Gene3D G3DSA:3.40.50.1000 42 61 2.2E-21 T 22-04-2016 IPR023214 HAD-like domain L21SP4_RS01095 9a95c836b86754daa96773ab1469f1d5 277 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 46 57 2.2E-6 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 L21SP4_RS01095 9a95c836b86754daa96773ab1469f1d5 277 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 140 153 2.2E-6 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 L21SP4_RS06885 e5f7667481fc653462b3a5cb23b04646 179 PANTHER PTHR36701 1 178 2.6E-57 T 22-04-2016 L21SP4_RS06885 e5f7667481fc653462b3a5cb23b04646 179 Pfam PF02677 Uncharacterized BCR, COG1636 12 178 5.7E-55 T 22-04-2016 IPR003828 Protein of unknown function DUF208 L21SP4_RS02345 1cf02a4c6d0a0726886ddc65ff6caffb 504 SUPERFAMILY SSF52402 197 445 1.19E-49 T 22-04-2016 L21SP4_RS02345 1cf02a4c6d0a0726886ddc65ff6caffb 504 Pfam PF00733 Asparagine synthase 203 353 2.8E-38 T 22-04-2016 IPR001962 Asparagine synthase GO:0004066|GO:0006529 L21SP4_RS02345 1cf02a4c6d0a0726886ddc65ff6caffb 504 Pfam PF00733 Asparagine synthase 358 489 3.1E-14 T 22-04-2016 IPR001962 Asparagine synthase GO:0004066|GO:0006529 L21SP4_RS02345 1cf02a4c6d0a0726886ddc65ff6caffb 504 Gene3D G3DSA:3.60.20.10 10 175 4.3E-26 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal L21SP4_RS02345 1cf02a4c6d0a0726886ddc65ff6caffb 504 PANTHER PTHR11772 98 503 4.7E-86 T 22-04-2016 L21SP4_RS02345 1cf02a4c6d0a0726886ddc65ff6caffb 504 Pfam PF13537 Glutamine amidotransferase domain 58 159 8.2E-11 T 22-04-2016 IPR017932 Glutamine amidotransferase type 2 domain L21SP4_RS02345 1cf02a4c6d0a0726886ddc65ff6caffb 504 PANTHER PTHR11772:SF2 98 503 4.7E-86 T 22-04-2016 L21SP4_RS02345 1cf02a4c6d0a0726886ddc65ff6caffb 504 Gene3D G3DSA:3.40.50.620 195 490 5.2E-62 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP4_RS02345 1cf02a4c6d0a0726886ddc65ff6caffb 504 SUPERFAMILY SSF56235 19 175 4.55E-26 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal L21SP4_RS04205 0492aa63befce9c7b1c943857cc4b92e 120 Gene3D G3DSA:3.30.1130.10 1 115 7.2E-42 T 22-04-2016 L21SP4_RS04205 0492aa63befce9c7b1c943857cc4b92e 120 PANTHER PTHR20941 1 116 2.0E-28 T 22-04-2016 L21SP4_RS04205 0492aa63befce9c7b1c943857cc4b92e 120 TIGRFAM TIGR00526 folB_dom: FolB domain 1 117 8.0E-31 T 22-04-2016 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 L21SP4_RS04205 0492aa63befce9c7b1c943857cc4b92e 120 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 2 114 1.2E-26 T 22-04-2016 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 L21SP4_RS04205 0492aa63befce9c7b1c943857cc4b92e 120 SUPERFAMILY SSF55620 1 115 2.0E-34 T 22-04-2016 L21SP4_RS04205 0492aa63befce9c7b1c943857cc4b92e 120 SMART SM00905 4 114 8.9E-45 T 22-04-2016 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 L21SP4_RS04205 0492aa63befce9c7b1c943857cc4b92e 120 Pfam PF02152 Dihydroneopterin aldolase 4 113 1.9E-35 T 22-04-2016 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 L21SP4_RS07090 57fe64267dc9462e3786868672815ea0 215 Hamap MF_00165 Thymidylate kinase [tmk]. 5 212 29.599 T 22-04-2016 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 L21SP4_RS07090 57fe64267dc9462e3786868672815ea0 215 SUPERFAMILY SSF52540 1 210 2.84E-52 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS07090 57fe64267dc9462e3786868672815ea0 215 PANTHER PTHR10344 1 210 5.0E-65 T 22-04-2016 L21SP4_RS07090 57fe64267dc9462e3786868672815ea0 215 Pfam PF02223 Thymidylate kinase 9 201 2.3E-48 T 22-04-2016 L21SP4_RS07090 57fe64267dc9462e3786868672815ea0 215 Gene3D G3DSA:3.40.50.300 4 210 5.7E-68 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS07090 57fe64267dc9462e3786868672815ea0 215 ProSitePatterns PS01331 Thymidylate kinase signature. 95 107 - T 22-04-2016 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 L21SP4_RS07090 57fe64267dc9462e3786868672815ea0 215 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 1 200 3.8E-49 T 22-04-2016 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 L21SP4_RS01825 8456667411eae2f4d6ddaf8dc6aeedf3 724 Pfam PF00884 Sulfatase 29 353 4.5E-68 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS01825 8456667411eae2f4d6ddaf8dc6aeedf3 724 PANTHER PTHR10342:SF199 1 478 5.1E-144 T 22-04-2016 L21SP4_RS01825 8456667411eae2f4d6ddaf8dc6aeedf3 724 Gene3D G3DSA:3.40.720.10 26 374 2.3E-105 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS01825 8456667411eae2f4d6ddaf8dc6aeedf3 724 PANTHER PTHR10342 1 478 5.1E-144 T 22-04-2016 L21SP4_RS01825 8456667411eae2f4d6ddaf8dc6aeedf3 724 Gene3D G3DSA:3.30.1120.10 377 461 2.0E-14 T 22-04-2016 L21SP4_RS01825 8456667411eae2f4d6ddaf8dc6aeedf3 724 ProSitePatterns PS00523 Sulfatases signature 1. 74 86 - T 22-04-2016 IPR024607 Sulfatase, conserved site L21SP4_RS01825 8456667411eae2f4d6ddaf8dc6aeedf3 724 SUPERFAMILY SSF53649 27 459 6.83E-122 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS06800 0e084cc8940db8705ef8ae8b55cac947 460 ProSitePatterns PS01219 Ammonium transporters signature. 198 223 - T 22-04-2016 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 L21SP4_RS06800 0e084cc8940db8705ef8ae8b55cac947 460 TIGRFAM TIGR00836 amt: ammonium transporter 39 451 2.1E-133 T 22-04-2016 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 L21SP4_RS06800 0e084cc8940db8705ef8ae8b55cac947 460 Pfam PF00909 Ammonium Transporter Family 41 451 2.0E-126 T 22-04-2016 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 L21SP4_RS06800 0e084cc8940db8705ef8ae8b55cac947 460 Gene3D G3DSA:1.10.3430.10 33 432 1.7E-125 T 22-04-2016 IPR029020 Ammonium/urea transporter L21SP4_RS06800 0e084cc8940db8705ef8ae8b55cac947 460 SUPERFAMILY SSF111352 36 432 3.14E-114 T 22-04-2016 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 L21SP4_RS06800 0e084cc8940db8705ef8ae8b55cac947 460 PANTHER PTHR11730:SF6 11 451 1.7E-182 T 22-04-2016 L21SP4_RS06800 0e084cc8940db8705ef8ae8b55cac947 460 PANTHER PTHR11730 11 451 1.7E-182 T 22-04-2016 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 L21SP4_RS07775 d9cfdf44a470c6a314af0149b7379e48 586 Pfam PF00263 Bacterial type II and III secretion system protein 371 549 3.0E-38 T 22-04-2016 IPR004846 Type II/III secretion system GO:0009306 L21SP4_RS07775 d9cfdf44a470c6a314af0149b7379e48 586 PANTHER PTHR30332 248 561 1.5E-51 T 22-04-2016 L21SP4_RS07775 d9cfdf44a470c6a314af0149b7379e48 586 PRINTS PR00811 Bacterial general secretion pathway protein D signature 366 390 2.5E-13 T 22-04-2016 IPR001775 GspD/PilQ family L21SP4_RS07775 d9cfdf44a470c6a314af0149b7379e48 586 PRINTS PR00811 Bacterial general secretion pathway protein D signature 285 295 2.5E-13 T 22-04-2016 IPR001775 GspD/PilQ family L21SP4_RS07775 d9cfdf44a470c6a314af0149b7379e48 586 PRINTS PR00811 Bacterial general secretion pathway protein D signature 514 532 2.5E-13 T 22-04-2016 IPR001775 GspD/PilQ family L21SP4_RS07775 d9cfdf44a470c6a314af0149b7379e48 586 PRINTS PR00811 Bacterial general secretion pathway protein D signature 537 551 2.5E-13 T 22-04-2016 IPR001775 GspD/PilQ family L21SP4_RS07775 d9cfdf44a470c6a314af0149b7379e48 586 PANTHER PTHR30332:SF0 248 561 1.5E-51 T 22-04-2016 L21SP4_RS11215 85a84ec85afe9c94591430a7bbabefd4 337 Pfam PF09587 Bacterial capsule synthesis protein PGA_cap 20 232 1.4E-33 T 22-04-2016 IPR019079 Capsule synthesis protein, CapA L21SP4_RS11215 85a84ec85afe9c94591430a7bbabefd4 337 PANTHER PTHR33393 29 232 2.2E-23 T 22-04-2016 L21SP4_RS11215 85a84ec85afe9c94591430a7bbabefd4 337 Gene3D G3DSA:3.60.21.10 168 221 6.6E-4 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like L21SP4_RS11215 85a84ec85afe9c94591430a7bbabefd4 337 SUPERFAMILY SSF56300 30 239 5.31E-16 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like L21SP4_RS11215 85a84ec85afe9c94591430a7bbabefd4 337 SMART SM00854 1 232 5.8E-26 T 22-04-2016 IPR019079 Capsule synthesis protein, CapA L21SP4_RS11215 85a84ec85afe9c94591430a7bbabefd4 337 PANTHER PTHR33393:SF2 29 232 2.2E-23 T 22-04-2016 L21SP4_RS01225 2f1058c6acf73a44b6e000dd8764a923 526 SUPERFAMILY SSF161070 123 520 2.09E-96 T 22-04-2016 L21SP4_RS01225 2f1058c6acf73a44b6e000dd8764a923 526 ProSitePatterns PS00610 Sodium:neurotransmitter symporter family signature 1. 29 43 - T 22-04-2016 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 L21SP4_RS01225 2f1058c6acf73a44b6e000dd8764a923 526 PANTHER PTHR11616:SF167 497 520 2.8E-160 T 22-04-2016 L21SP4_RS01225 2f1058c6acf73a44b6e000dd8764a923 526 PANTHER PTHR11616:SF167 128 399 2.8E-160 T 22-04-2016 L21SP4_RS01225 2f1058c6acf73a44b6e000dd8764a923 526 PANTHER PTHR11616:SF167 4 85 2.8E-160 T 22-04-2016 L21SP4_RS01225 2f1058c6acf73a44b6e000dd8764a923 526 PANTHER PTHR11616:SF167 422 470 2.8E-160 T 22-04-2016 L21SP4_RS01225 2f1058c6acf73a44b6e000dd8764a923 526 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 338 357 5.8E-17 T 22-04-2016 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 L21SP4_RS01225 2f1058c6acf73a44b6e000dd8764a923 526 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 13 34 5.8E-17 T 22-04-2016 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 L21SP4_RS01225 2f1058c6acf73a44b6e000dd8764a923 526 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 42 61 5.8E-17 T 22-04-2016 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 L21SP4_RS01225 2f1058c6acf73a44b6e000dd8764a923 526 Pfam PF00209 Sodium:neurotransmitter symporter family 5 87 3.3E-24 T 22-04-2016 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 L21SP4_RS01225 2f1058c6acf73a44b6e000dd8764a923 526 Pfam PF00209 Sodium:neurotransmitter symporter family 191 405 4.8E-35 T 22-04-2016 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 L21SP4_RS01225 2f1058c6acf73a44b6e000dd8764a923 526 PANTHER PTHR11616 497 520 2.8E-160 T 22-04-2016 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 L21SP4_RS01225 2f1058c6acf73a44b6e000dd8764a923 526 PANTHER PTHR11616 128 399 2.8E-160 T 22-04-2016 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 L21SP4_RS01225 2f1058c6acf73a44b6e000dd8764a923 526 PANTHER PTHR11616 4 85 2.8E-160 T 22-04-2016 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 L21SP4_RS01225 2f1058c6acf73a44b6e000dd8764a923 526 PANTHER PTHR11616 422 470 2.8E-160 T 22-04-2016 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 L21SP4_RS01225 2f1058c6acf73a44b6e000dd8764a923 526 SUPERFAMILY SSF161070 5 106 4.97E-37 T 22-04-2016 L21SP4_RS04260 c739535915d992bdcdf273456dbd9c05 286 Gene3D G3DSA:3.60.21.10 22 269 1.6E-45 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like L21SP4_RS04260 c739535915d992bdcdf273456dbd9c05 286 PANTHER PTHR16509:SF1 24 281 1.4E-31 T 22-04-2016 L21SP4_RS04260 c739535915d992bdcdf273456dbd9c05 286 SUPERFAMILY SSF56300 23 269 2.85E-50 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like L21SP4_RS04260 c739535915d992bdcdf273456dbd9c05 286 PANTHER PTHR16509 24 281 1.4E-31 T 22-04-2016 L21SP4_RS04260 c739535915d992bdcdf273456dbd9c05 286 Pfam PF00149 Calcineurin-like phosphoesterase 25 230 5.4E-15 T 22-04-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 L21SP4_RS00025 7ec92863ea46290c0f007f73a42990dd 400 PANTHER PTHR12526:SF141 79 398 1.5E-24 T 22-04-2016 L21SP4_RS00025 7ec92863ea46290c0f007f73a42990dd 400 PANTHER PTHR12526:SF141 1 43 1.5E-24 T 22-04-2016 L21SP4_RS00025 7ec92863ea46290c0f007f73a42990dd 400 Pfam PF13692 Glycosyl transferases group 1 223 362 2.7E-25 T 22-04-2016 L21SP4_RS00025 7ec92863ea46290c0f007f73a42990dd 400 PANTHER PTHR12526 79 398 1.5E-24 T 22-04-2016 L21SP4_RS00025 7ec92863ea46290c0f007f73a42990dd 400 PANTHER PTHR12526 1 43 1.5E-24 T 22-04-2016 L21SP4_RS00025 7ec92863ea46290c0f007f73a42990dd 400 SUPERFAMILY SSF53756 2 396 9.81E-42 T 22-04-2016 L21SP4_RS00025 7ec92863ea46290c0f007f73a42990dd 400 Gene3D G3DSA:3.40.50.2000 221 374 6.4E-5 T 22-04-2016 L21SP4_RS03505 c8608595c590deacfd7cd258cf6d8a72 470 Gene3D G3DSA:1.20.1600.10 50 460 5.3E-101 T 22-04-2016 L21SP4_RS03505 c8608595c590deacfd7cd258cf6d8a72 470 PANTHER PTHR30203 1 463 2.2E-82 T 22-04-2016 L21SP4_RS03505 c8608595c590deacfd7cd258cf6d8a72 470 PANTHER PTHR30203:SF3 1 463 2.2E-82 T 22-04-2016 L21SP4_RS03505 c8608595c590deacfd7cd258cf6d8a72 470 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 40 457 1.7E-90 T 22-04-2016 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 L21SP4_RS03505 c8608595c590deacfd7cd258cf6d8a72 470 Pfam PF02321 Outer membrane efflux protein 279 456 6.3E-24 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 L21SP4_RS03505 c8608595c590deacfd7cd258cf6d8a72 470 Pfam PF02321 Outer membrane efflux protein 59 248 5.2E-22 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 L21SP4_RS03505 c8608595c590deacfd7cd258cf6d8a72 470 SUPERFAMILY SSF56954 2 460 2.88E-97 T 22-04-2016 L21SP4_RS10375 625e1f4f3c14db6bc3778d1b3f782aaf 206 SUPERFAMILY SSF53328 2 200 1.57E-61 T 22-04-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 L21SP4_RS10375 625e1f4f3c14db6bc3778d1b3f782aaf 206 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 136 159 - T 22-04-2016 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 L21SP4_RS10375 625e1f4f3c14db6bc3778d1b3f782aaf 206 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 3 190 31.835 T 22-04-2016 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|UniPathway: UPA00074 L21SP4_RS10375 625e1f4f3c14db6bc3778d1b3f782aaf 206 Pfam PF00551 Formyl transferase 3 184 3.4E-53 T 22-04-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 L21SP4_RS10375 625e1f4f3c14db6bc3778d1b3f782aaf 206 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 3 194 7.3E-67 T 22-04-2016 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|UniPathway: UPA00074 L21SP4_RS10375 625e1f4f3c14db6bc3778d1b3f782aaf 206 PANTHER PTHR10520 1 196 2.3E-91 T 22-04-2016 L21SP4_RS10375 625e1f4f3c14db6bc3778d1b3f782aaf 206 Gene3D G3DSA:3.40.50.170 2 197 6.4E-68 T 22-04-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 L21SP4_RS10570 5ca241006eba730a4f8b6b5d7c8d4aca 399 SMART SM00382 55 252 2.5E-19 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS10570 5ca241006eba730a4f8b6b5d7c8d4aca 399 SUPERFAMILY SSF54631 276 395 1.77E-19 T 22-04-2016 L21SP4_RS10570 5ca241006eba730a4f8b6b5d7c8d4aca 399 Gene3D G3DSA:3.10.580.10 274 393 3.9E-21 T 22-04-2016 L21SP4_RS10570 5ca241006eba730a4f8b6b5d7c8d4aca 399 Pfam PF00005 ABC transporter 47 194 2.0E-32 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 L21SP4_RS10570 5ca241006eba730a4f8b6b5d7c8d4aca 399 PANTHER PTHR24220 8 18 1.7E-157 T 22-04-2016 L21SP4_RS10570 5ca241006eba730a4f8b6b5d7c8d4aca 399 PANTHER PTHR24220 43 273 1.7E-157 T 22-04-2016 L21SP4_RS10570 5ca241006eba730a4f8b6b5d7c8d4aca 399 PANTHER PTHR24220 291 315 1.7E-157 T 22-04-2016 L21SP4_RS10570 5ca241006eba730a4f8b6b5d7c8d4aca 399 Gene3D G3DSA:3.40.50.300 43 268 7.0E-75 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS10570 5ca241006eba730a4f8b6b5d7c8d4aca 399 SUPERFAMILY SSF52540 38 272 3.13E-71 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS10570 5ca241006eba730a4f8b6b5d7c8d4aca 399 ProSitePatterns PS00211 ABC transporters family signature. 167 181 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 L21SP4_RS10570 5ca241006eba730a4f8b6b5d7c8d4aca 399 PANTHER PTHR24220:SF374 8 18 1.7E-157 T 22-04-2016 L21SP4_RS10570 5ca241006eba730a4f8b6b5d7c8d4aca 399 PANTHER PTHR24220:SF374 43 273 1.7E-157 T 22-04-2016 L21SP4_RS10570 5ca241006eba730a4f8b6b5d7c8d4aca 399 PANTHER PTHR24220:SF374 291 315 1.7E-157 T 22-04-2016 L21SP4_RS10570 5ca241006eba730a4f8b6b5d7c8d4aca 399 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 38 393 7.3E-135 T 22-04-2016 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 L21SP4_RS10570 5ca241006eba730a4f8b6b5d7c8d4aca 399 Pfam PF00571 CBS domain 341 392 1.0E-5 T 22-04-2016 IPR000644 CBS domain L21SP4_RS03805 13c24bfcfbc108d6101327a54cd482a6 460 PRINTS PR00171 Sugar transporter signature 99 118 4.5E-24 T 22-04-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 L21SP4_RS03805 13c24bfcfbc108d6101327a54cd482a6 460 PRINTS PR00171 Sugar transporter signature 265 275 4.5E-24 T 22-04-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 L21SP4_RS03805 13c24bfcfbc108d6101327a54cd482a6 460 PRINTS PR00171 Sugar transporter signature 385 397 4.5E-24 T 22-04-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 L21SP4_RS03805 13c24bfcfbc108d6101327a54cd482a6 460 PRINTS PR00171 Sugar transporter signature 362 383 4.5E-24 T 22-04-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 L21SP4_RS03805 13c24bfcfbc108d6101327a54cd482a6 460 PRINTS PR00171 Sugar transporter signature 16 26 4.5E-24 T 22-04-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 L21SP4_RS03805 13c24bfcfbc108d6101327a54cd482a6 460 PANTHER PTHR23500:SF22 1 457 1.0E-195 T 22-04-2016 L21SP4_RS03805 13c24bfcfbc108d6101327a54cd482a6 460 PANTHER PTHR23500 1 457 1.0E-195 T 22-04-2016 L21SP4_RS03805 13c24bfcfbc108d6101327a54cd482a6 460 ProSitePatterns PS00216 Sugar transport proteins signature 1. 62 79 - T 22-04-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 L21SP4_RS03805 13c24bfcfbc108d6101327a54cd482a6 460 ProSitePatterns PS00216 Sugar transport proteins signature 1. 309 326 - T 22-04-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 L21SP4_RS03805 13c24bfcfbc108d6101327a54cd482a6 460 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 3 457 4.5E-111 T 22-04-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 L21SP4_RS03805 13c24bfcfbc108d6101327a54cd482a6 460 Gene3D G3DSA:1.20.1250.20 253 456 9.1E-20 T 22-04-2016 L21SP4_RS03805 13c24bfcfbc108d6101327a54cd482a6 460 Gene3D G3DSA:1.20.1250.20 12 203 7.8E-23 T 22-04-2016 L21SP4_RS03805 13c24bfcfbc108d6101327a54cd482a6 460 Pfam PF00083 Sugar (and other) transporter 10 457 3.5E-114 T 22-04-2016 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 L21SP4_RS03805 13c24bfcfbc108d6101327a54cd482a6 460 ProSitePatterns PS00217 Sugar transport proteins signature 2. 104 129 - T 22-04-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 L21SP4_RS03805 13c24bfcfbc108d6101327a54cd482a6 460 SUPERFAMILY SSF103473 11 457 7.46E-65 T 22-04-2016 IPR020846 Major facilitator superfamily domain L21SP4_RS03535 877ef2bb70a3027446b2fcf30a422088 416 ProSitePatterns PS00874 Bacterial type II secretion system protein F signature. 176 204 - T 22-04-2016 IPR001992 Type II secretion system conserved site GO:0009306|GO:0016020 L21SP4_RS03535 877ef2bb70a3027446b2fcf30a422088 416 Pfam PF00482 Type II secretion system (T2SS), protein F 284 405 4.9E-25 T 22-04-2016 IPR018076 Type II secretion system F domain L21SP4_RS03535 877ef2bb70a3027446b2fcf30a422088 416 Pfam PF00482 Type II secretion system (T2SS), protein F 81 204 5.0E-23 T 22-04-2016 IPR018076 Type II secretion system F domain L21SP4_RS03535 877ef2bb70a3027446b2fcf30a422088 416 PRINTS PR00812 Bacterial general secretion pathway protein F signature 395 414 8.8E-13 T 22-04-2016 IPR003004 GspF/PilC family L21SP4_RS03535 877ef2bb70a3027446b2fcf30a422088 416 PRINTS PR00812 Bacterial general secretion pathway protein F signature 379 393 8.8E-13 T 22-04-2016 IPR003004 GspF/PilC family L21SP4_RS03535 877ef2bb70a3027446b2fcf30a422088 416 PRINTS PR00812 Bacterial general secretion pathway protein F signature 77 89 8.8E-13 T 22-04-2016 IPR003004 GspF/PilC family L21SP4_RS03535 877ef2bb70a3027446b2fcf30a422088 416 PRINTS PR00812 Bacterial general secretion pathway protein F signature 176 204 8.8E-13 T 22-04-2016 IPR003004 GspF/PilC family L21SP4_RS03535 877ef2bb70a3027446b2fcf30a422088 416 PANTHER PTHR30012:SF0 2 415 4.3E-117 T 22-04-2016 L21SP4_RS03535 877ef2bb70a3027446b2fcf30a422088 416 PANTHER PTHR30012 2 415 4.3E-117 T 22-04-2016 L21SP4_RS06790 4fd435d24b6ff456763e897ec2e23401 248 Pfam PF09694 Bacterial protein of unknown function (Gcw_chp) 19 221 4.5E-6 T 22-04-2016 IPR010239 Conserved hypothetical protein CHP02001 L21SP4_RS00420 aba19ec51342cf70170786be66170563 247 Pfam PF00994 Probable molybdopterin binding domain 7 172 1.2E-26 T 22-04-2016 IPR001453 MoaB/Mog domain L21SP4_RS00420 aba19ec51342cf70170786be66170563 247 SMART SM00852 6 174 1.9E-31 T 22-04-2016 IPR001453 MoaB/Mog domain L21SP4_RS00420 aba19ec51342cf70170786be66170563 247 SUPERFAMILY SSF53218 4 203 4.45E-31 T 22-04-2016 IPR001453 MoaB/Mog domain L21SP4_RS00420 aba19ec51342cf70170786be66170563 247 PANTHER PTHR13939 3 237 2.6E-61 T 22-04-2016 L21SP4_RS00420 aba19ec51342cf70170786be66170563 247 Gene3D G3DSA:3.40.980.10 5 211 1.2E-28 T 22-04-2016 IPR001453 MoaB/Mog domain L21SP4_RS09755 323f9315d4614339baffbfe5be8245a3 154 PANTHER PTHR33387:SF3 1 154 1.9E-52 T 22-04-2016 L21SP4_RS09755 323f9315d4614339baffbfe5be8245a3 154 Gene3D G3DSA:2.60.120.10 1 153 1.8E-52 T 22-04-2016 IPR014710 RmlC-like jelly roll fold L21SP4_RS09755 323f9315d4614339baffbfe5be8245a3 154 Pfam PF06172 Cupin superfamily (DUF985) 1 131 1.7E-38 T 22-04-2016 IPR009327 Cupin domain of unknown function DUF985 L21SP4_RS09755 323f9315d4614339baffbfe5be8245a3 154 SUPERFAMILY SSF51182 1 153 6.58E-49 T 22-04-2016 IPR011051 RmlC-like cupin domain L21SP4_RS09755 323f9315d4614339baffbfe5be8245a3 154 PANTHER PTHR33387 1 154 1.9E-52 T 22-04-2016 L21SP4_RS09960 52cdf1db7440d162590b109146d4f796 245 PANTHER PTHR31223:SF1 71 239 6.5E-60 T 22-04-2016 L21SP4_RS09960 52cdf1db7440d162590b109146d4f796 245 Pfam PF03641 Possible lysine decarboxylase 106 235 2.8E-30 T 22-04-2016 IPR031100 LOG family L21SP4_RS09960 52cdf1db7440d162590b109146d4f796 245 SUPERFAMILY SSF102405 15 236 1.68E-52 T 22-04-2016 L21SP4_RS09960 52cdf1db7440d162590b109146d4f796 245 Gene3D G3DSA:3.40.50.450 22 243 2.9E-63 T 22-04-2016 L21SP4_RS09960 52cdf1db7440d162590b109146d4f796 245 PANTHER PTHR31223 71 239 6.5E-60 T 22-04-2016 L21SP4_RS10415 a7cc61b03c1149edd73e4e3a84ff5acf 284 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 22 277 2.0E-96 T 22-04-2016 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614|UniPathway: UPA00077 L21SP4_RS10415 a7cc61b03c1149edd73e4e3a84ff5acf 284 PANTHER PTHR20941:SF1 12 283 5.2E-117 T 22-04-2016 L21SP4_RS10415 a7cc61b03c1149edd73e4e3a84ff5acf 284 PANTHER PTHR20941 12 283 5.2E-117 T 22-04-2016 L21SP4_RS10415 a7cc61b03c1149edd73e4e3a84ff5acf 284 SUPERFAMILY SSF51717 7 280 1.7E-100 T 22-04-2016 IPR011005 Dihydropteroate synthase-like GO:0044237 L21SP4_RS10415 a7cc61b03c1149edd73e4e3a84ff5acf 284 Gene3D G3DSA:3.20.20.20 7 280 1.3E-107 T 22-04-2016 IPR000489 Pterin-binding domain GO:0042558 L21SP4_RS10415 a7cc61b03c1149edd73e4e3a84ff5acf 284 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 22 37 - T 22-04-2016 IPR000489 Pterin-binding domain GO:0042558 L21SP4_RS10415 a7cc61b03c1149edd73e4e3a84ff5acf 284 Pfam PF00809 Pterin binding enzyme 23 263 8.3E-85 T 22-04-2016 IPR000489 Pterin-binding domain GO:0042558 L21SP4_RS08260 4421d77d3b4fde050f7cbc2d7e939960 717 PANTHER PTHR30332:SF0 317 637 1.1E-40 T 22-04-2016 L21SP4_RS08260 4421d77d3b4fde050f7cbc2d7e939960 717 Pfam PF00263 Bacterial type II and III secretion system protein 441 632 3.6E-32 T 22-04-2016 IPR004846 Type II/III secretion system GO:0009306 L21SP4_RS08260 4421d77d3b4fde050f7cbc2d7e939960 717 PRINTS PR00811 Bacterial general secretion pathway protein D signature 343 353 7.2E-11 T 22-04-2016 IPR001775 GspD/PilQ family L21SP4_RS08260 4421d77d3b4fde050f7cbc2d7e939960 717 PRINTS PR00811 Bacterial general secretion pathway protein D signature 597 615 7.2E-11 T 22-04-2016 IPR001775 GspD/PilQ family L21SP4_RS08260 4421d77d3b4fde050f7cbc2d7e939960 717 PRINTS PR00811 Bacterial general secretion pathway protein D signature 620 634 7.2E-11 T 22-04-2016 IPR001775 GspD/PilQ family L21SP4_RS08260 4421d77d3b4fde050f7cbc2d7e939960 717 PANTHER PTHR30332 317 637 1.1E-40 T 22-04-2016 L21SP4_RS10485 4c4734e1203b6df110406ed48b2d5da3 443 PANTHER PTHR19446:SF383 67 365 8.6E-65 T 22-04-2016 L21SP4_RS10485 4c4734e1203b6df110406ed48b2d5da3 443 Pfam PF08388 Group II intron, maturase-specific domain 354 421 2.8E-14 T 22-04-2016 IPR013597 Group II intron, maturase-specific L21SP4_RS10485 4c4734e1203b6df110406ed48b2d5da3 443 PANTHER PTHR19446 67 365 8.6E-65 T 22-04-2016 L21SP4_RS10485 4c4734e1203b6df110406ed48b2d5da3 443 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 50 418 7.2E-110 T 22-04-2016 IPR030931 Group II intron reverse transcriptase/maturase L21SP4_RS10485 4c4734e1203b6df110406ed48b2d5da3 443 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 109 329 3.0E-35 T 22-04-2016 IPR000477 Reverse transcriptase domain L21SP4_RS10485 4c4734e1203b6df110406ed48b2d5da3 443 SUPERFAMILY SSF56672 56 344 7.63E-46 T 22-04-2016 L21SP4_RS11060 497c943c4164c4545256964f70559062 446 Pfam PF10415 Fumarase C C-terminus 392 439 3.9E-9 T 22-04-2016 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|UniPathway: UPA00223 L21SP4_RS11060 497c943c4164c4545256964f70559062 446 PANTHER PTHR11444:SF25 1 439 1.2E-172 T 22-04-2016 L21SP4_RS11060 497c943c4164c4545256964f70559062 446 Pfam PF00206 Lyase 2 326 7.3E-84 T 22-04-2016 IPR022761 Fumarate lyase, N-terminal L21SP4_RS11060 497c943c4164c4545256964f70559062 446 ProSitePatterns PS00163 Fumarate lyases signature. 301 310 - T 22-04-2016 IPR020557 Fumarate lyase, conserved site GO:0003824 L21SP4_RS11060 497c943c4164c4545256964f70559062 446 SUPERFAMILY SSF48557 1 439 5.81E-120 T 22-04-2016 IPR008948 L-Aspartase-like GO:0003824 L21SP4_RS11060 497c943c4164c4545256964f70559062 446 Gene3D G3DSA:1.20.200.10 124 387 1.1E-76 T 22-04-2016 L21SP4_RS11060 497c943c4164c4545256964f70559062 446 Gene3D G3DSA:1.10.275.10 1 123 2.9E-45 T 22-04-2016 IPR024083 Fumarase/histidase, N-terminal L21SP4_RS11060 497c943c4164c4545256964f70559062 446 PRINTS PR00149 Fumarate lyase superfamily signature 301 317 1.9E-22 T 22-04-2016 IPR000362 Fumarate lyase family L21SP4_RS11060 497c943c4164c4545256964f70559062 446 PRINTS PR00149 Fumarate lyase superfamily signature 119 137 1.9E-22 T 22-04-2016 IPR000362 Fumarate lyase family L21SP4_RS11060 497c943c4164c4545256964f70559062 446 PRINTS PR00149 Fumarate lyase superfamily signature 255 282 1.9E-22 T 22-04-2016 IPR000362 Fumarate lyase family L21SP4_RS11060 497c943c4164c4545256964f70559062 446 PRINTS PR00149 Fumarate lyase superfamily signature 164 182 1.9E-22 T 22-04-2016 IPR000362 Fumarate lyase family L21SP4_RS11060 497c943c4164c4545256964f70559062 446 PANTHER PTHR11444 1 439 1.2E-172 T 22-04-2016 IPR000362 Fumarate lyase family L21SP4_RS11060 497c943c4164c4545256964f70559062 446 Gene3D G3DSA:1.10.40.30 392 439 2.3E-8 T 22-04-2016 L21SP4_RS01325 e43733d959d2484174910486f238a720 290 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 192 288 1.5E-13 T 22-04-2016 IPR007831 General secretory system II, protein E, N-terminal GO:0005524|GO:0006810 L21SP4_RS01325 e43733d959d2484174910486f238a720 290 Gene3D G3DSA:1.25.40.10 134 156 9.3E-6 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS01325 e43733d959d2484174910486f238a720 290 Gene3D G3DSA:1.25.40.10 22 74 9.3E-6 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS01325 e43733d959d2484174910486f238a720 290 SUPERFAMILY SSF160246 165 283 4.05E-16 T 22-04-2016 L21SP4_RS01325 e43733d959d2484174910486f238a720 290 SUPERFAMILY SSF48452 23 92 3.87E-5 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS05360 ed213aa487ea31d207ad272793dae37f 263 SUPERFAMILY SSF55120 1 248 7.62E-83 T 22-04-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 L21SP4_RS05360 ed213aa487ea31d207ad272793dae37f 263 PIRSF PIRSF001430 1 254 4.6E-79 T 22-04-2016 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 L21SP4_RS05360 ed213aa487ea31d207ad272793dae37f 263 Gene3D G3DSA:3.30.70.660 107 243 5.4E-44 T 22-04-2016 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 L21SP4_RS05360 ed213aa487ea31d207ad272793dae37f 263 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 5 240 9.9E-59 T 22-04-2016 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 L21SP4_RS05360 ed213aa487ea31d207ad272793dae37f 263 Gene3D G3DSA:3.30.70.580 1 105 3.0E-38 T 22-04-2016 IPR020094 Pseudouridine synthase I, TruA, N-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 L21SP4_RS05360 ed213aa487ea31d207ad272793dae37f 263 Pfam PF01416 tRNA pseudouridine synthase 144 245 1.8E-25 T 22-04-2016 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 L21SP4_RS05360 ed213aa487ea31d207ad272793dae37f 263 Pfam PF01416 tRNA pseudouridine synthase 7 104 1.3E-10 T 22-04-2016 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 L21SP4_RS05360 ed213aa487ea31d207ad272793dae37f 263 PANTHER PTHR11142 1 245 4.5E-91 T 22-04-2016 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 L21SP4_RS05360 ed213aa487ea31d207ad272793dae37f 263 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 2 245 35.456 T 22-04-2016 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 L21SP4_RS06455 d40242a80fb4b156ba0c4f27f72fa441 494 Pfam PF03050 Transposase IS66 family 175 456 5.2E-60 T 22-04-2016 IPR004291 Transposase, IS66 L21SP4_RS06455 d40242a80fb4b156ba0c4f27f72fa441 494 PANTHER PTHR33678 17 494 8.2E-126 T 22-04-2016 L21SP4_RS06455 d40242a80fb4b156ba0c4f27f72fa441 494 PANTHER PTHR33678:SF2 17 494 8.2E-126 T 22-04-2016 L21SP4_RS06455 d40242a80fb4b156ba0c4f27f72fa441 494 Pfam PF13005 zinc-finger binding domain of transposase IS66 116 159 2.1E-7 T 22-04-2016 IPR024474 Zinc-finger binding domain of transposase IS66 L21SP4_RS03230 7dde9adf0262069fc726c8a8c0b0ddfb 151 SUPERFAMILY SSF47413 77 127 8.85E-7 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 L21SP4_RS03230 7dde9adf0262069fc726c8a8c0b0ddfb 151 Gene3D G3DSA:1.10.260.40 78 127 2.0E-6 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 L21SP4_RS04155 a1e6a4f43b17cb1fbbc3db994c18fdfd 321 PANTHER PTHR36838 4 321 1.8E-24 T 22-04-2016 L21SP4_RS04155 a1e6a4f43b17cb1fbbc3db994c18fdfd 321 Pfam PF03547 Membrane transport protein 11 149 2.1E-17 T 22-04-2016 IPR004776 Auxin efflux carrier GO:0016021|GO:0055085 L21SP4_RS04155 a1e6a4f43b17cb1fbbc3db994c18fdfd 321 Pfam PF03547 Membrane transport protein 193 317 3.0E-14 T 22-04-2016 IPR004776 Auxin efflux carrier GO:0016021|GO:0055085 L21SP4_RS04950 3dd4c8d1e7eae390b5d8cb55cedb66ba 341 Pfam PF13519 von Willebrand factor type A domain 86 210 2.2E-18 T 22-04-2016 IPR002035 von Willebrand factor, type A L21SP4_RS04950 3dd4c8d1e7eae390b5d8cb55cedb66ba 341 PANTHER PTHR22550 7 340 3.1E-34 T 22-04-2016 L21SP4_RS04950 3dd4c8d1e7eae390b5d8cb55cedb66ba 341 Gene3D G3DSA:3.40.50.410 85 289 4.5E-19 T 22-04-2016 IPR002035 von Willebrand factor, type A L21SP4_RS04950 3dd4c8d1e7eae390b5d8cb55cedb66ba 341 SUPERFAMILY SSF53300 81 290 2.97E-27 T 22-04-2016 IPR002035 von Willebrand factor, type A L21SP4_RS04950 3dd4c8d1e7eae390b5d8cb55cedb66ba 341 PANTHER PTHR22550:SF8 7 340 3.1E-34 T 22-04-2016 L21SP4_RS04950 3dd4c8d1e7eae390b5d8cb55cedb66ba 341 SMART SM00327 81 266 1.1E-13 T 22-04-2016 IPR002035 von Willebrand factor, type A L21SP4_RS07240 86f5eb1399478c58039f973d1eda757d 648 Pfam PF00884 Sulfatase 42 370 9.4E-65 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS07240 86f5eb1399478c58039f973d1eda757d 648 Gene3D G3DSA:3.30.1120.10 397 479 2.0E-13 T 22-04-2016 L21SP4_RS07240 86f5eb1399478c58039f973d1eda757d 648 Gene3D G3DSA:3.40.720.10 41 390 3.3E-95 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS07240 86f5eb1399478c58039f973d1eda757d 648 SUPERFAMILY SSF53649 42 475 2.18E-111 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS07240 86f5eb1399478c58039f973d1eda757d 648 PANTHER PTHR10342 14 500 3.4E-133 T 22-04-2016 L21SP4_RS07240 86f5eb1399478c58039f973d1eda757d 648 PANTHER PTHR10342:SF199 14 500 3.4E-133 T 22-04-2016 L21SP4_RS01780 42b3dfe96bbdc5d0345390673f6d9260 324 PANTHER PTHR30146 3 213 1.5E-38 T 22-04-2016 L21SP4_RS01780 42b3dfe96bbdc5d0345390673f6d9260 324 Gene3D G3DSA:3.40.50.2300 174 312 1.2E-6 T 22-04-2016 L21SP4_RS01780 42b3dfe96bbdc5d0345390673f6d9260 324 SMART SM00354 3 73 4.4E-17 T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 L21SP4_RS01780 42b3dfe96bbdc5d0345390673f6d9260 324 Gene3D G3DSA:1.10.260.40 3 53 2.6E-19 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 L21SP4_RS01780 42b3dfe96bbdc5d0345390673f6d9260 324 SUPERFAMILY SSF53822 60 303 2.78E-18 T 22-04-2016 IPR028082 Periplasmic binding protein-like I L21SP4_RS01780 42b3dfe96bbdc5d0345390673f6d9260 324 Gene3D G3DSA:3.40.50.2300 54 173 2.0E-18 T 22-04-2016 L21SP4_RS01780 42b3dfe96bbdc5d0345390673f6d9260 324 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 50 5.1E-13 T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 L21SP4_RS01780 42b3dfe96bbdc5d0345390673f6d9260 324 SUPERFAMILY SSF47413 2 60 8.04E-16 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 L21SP4_RS07280 0de62142ebf55a3f302da33246c1e3b8 539 PANTHER PTHR10357 181 252 5.2E-95 T 22-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 L21SP4_RS07280 0de62142ebf55a3f302da33246c1e3b8 539 PANTHER PTHR10357 269 387 5.2E-95 T 22-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 L21SP4_RS07280 0de62142ebf55a3f302da33246c1e3b8 539 PANTHER PTHR10357 2 164 5.2E-95 T 22-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 L21SP4_RS07280 0de62142ebf55a3f302da33246c1e3b8 539 Gene3D G3DSA:3.20.20.80 2 102 2.6E-86 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP4_RS07280 0de62142ebf55a3f302da33246c1e3b8 539 Gene3D G3DSA:3.20.20.80 182 444 2.6E-86 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP4_RS07280 0de62142ebf55a3f302da33246c1e3b8 539 SMART SM00642 12 402 5.2E-65 T 22-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 L21SP4_RS07280 0de62142ebf55a3f302da33246c1e3b8 539 Gene3D G3DSA:3.90.400.10 103 162 1.2E-10 T 22-04-2016 L21SP4_RS07280 0de62142ebf55a3f302da33246c1e3b8 539 PANTHER PTHR10357:SF11 422 482 5.2E-95 T 22-04-2016 L21SP4_RS07280 0de62142ebf55a3f302da33246c1e3b8 539 SUPERFAMILY SSF51011 447 526 7.2E-7 T 22-04-2016 L21SP4_RS07280 0de62142ebf55a3f302da33246c1e3b8 539 Pfam PF00128 Alpha amylase, catalytic domain 27 363 1.9E-60 T 22-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 L21SP4_RS07280 0de62142ebf55a3f302da33246c1e3b8 539 Gene3D G3DSA:2.60.40.1180 447 526 2.3E-8 T 22-04-2016 IPR013780 Glycosyl hydrolase, all-beta L21SP4_RS07280 0de62142ebf55a3f302da33246c1e3b8 539 PANTHER PTHR10357:SF11 181 252 5.2E-95 T 22-04-2016 L21SP4_RS07280 0de62142ebf55a3f302da33246c1e3b8 539 PANTHER PTHR10357:SF11 269 387 5.2E-95 T 22-04-2016 L21SP4_RS07280 0de62142ebf55a3f302da33246c1e3b8 539 PANTHER PTHR10357:SF11 2 164 5.2E-95 T 22-04-2016 L21SP4_RS07280 0de62142ebf55a3f302da33246c1e3b8 539 SUPERFAMILY SSF51445 2 443 4.82E-99 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily L21SP4_RS07280 0de62142ebf55a3f302da33246c1e3b8 539 PANTHER PTHR10357 422 482 5.2E-95 T 22-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 L21SP4_RS01715 2daad0e7dbaad50a8fe68c32a033b05e 1181 Pfam PF14579 Helix-hairpin-helix motif 808 896 1.5E-24 T 22-04-2016 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 L21SP4_RS01715 2daad0e7dbaad50a8fe68c32a033b05e 1181 Gene3D G3DSA:3.20.20.140 8 260 9.3E-49 T 22-04-2016 L21SP4_RS01715 2daad0e7dbaad50a8fe68c32a033b05e 1181 SMART SM00481 9 76 3.5E-29 T 22-04-2016 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 L21SP4_RS01715 2daad0e7dbaad50a8fe68c32a033b05e 1181 PANTHER PTHR32294:SF0 4 1161 0.0 T 22-04-2016 L21SP4_RS01715 2daad0e7dbaad50a8fe68c32a033b05e 1181 PANTHER PTHR32294 4 1161 0.0 T 22-04-2016 L21SP4_RS01715 2daad0e7dbaad50a8fe68c32a033b05e 1181 Pfam PF02811 PHP domain 10 180 1.1E-49 T 22-04-2016 IPR004013 PHP domain GO:0003824 L21SP4_RS01715 2daad0e7dbaad50a8fe68c32a033b05e 1181 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 303 733 1.6E-167 T 22-04-2016 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 L21SP4_RS01715 2daad0e7dbaad50a8fe68c32a033b05e 1181 SUPERFAMILY SSF89550 8 270 2.75E-35 T 22-04-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 L21SP4_RS01715 2daad0e7dbaad50a8fe68c32a033b05e 1181 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 8 1033 0.0 T 22-04-2016 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 L21SP4_RS02770 9a1b128cc336ca8decf16615627d34a3 385 SUPERFAMILY SSF51726 189 379 4.36E-13 T 22-04-2016 L21SP4_RS02770 9a1b128cc336ca8decf16615627d34a3 385 Gene3D G3DSA:3.20.20.210 175 381 8.9E-12 T 22-04-2016 L21SP4_RS10610 ef56597bdd6b8bb66d812a130453edcf 275 Gene3D G3DSA:3.40.50.300 17 263 2.0E-81 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS10610 ef56597bdd6b8bb66d812a130453edcf 275 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 241 268 1.8E-6 T 22-04-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 L21SP4_RS10610 ef56597bdd6b8bb66d812a130453edcf 275 PANTHER PTHR24220 19 266 1.8E-124 T 22-04-2016 L21SP4_RS10610 ef56597bdd6b8bb66d812a130453edcf 275 SUPERFAMILY SSF52540 17 261 3.48E-72 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS10610 ef56597bdd6b8bb66d812a130453edcf 275 PANTHER PTHR24220:SF336 19 266 1.8E-124 T 22-04-2016 L21SP4_RS10610 ef56597bdd6b8bb66d812a130453edcf 275 Pfam PF00005 ABC transporter 38 189 4.5E-29 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 L21SP4_RS10610 ef56597bdd6b8bb66d812a130453edcf 275 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 L21SP4_RS10610 ef56597bdd6b8bb66d812a130453edcf 275 SMART SM00382 46 239 6.5E-13 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS07365 e2e6dca881e05a963a773820ebfe176f 414 Pfam PF00483 Nucleotidyl transferase 8 267 3.6E-61 T 22-04-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Reactome: REACT_17015 L21SP4_RS07365 e2e6dca881e05a963a773820ebfe176f 414 Gene3D G3DSA:2.160.10.10 327 368 6.5E-5 T 22-04-2016 L21SP4_RS07365 e2e6dca881e05a963a773820ebfe176f 414 ProSitePatterns PS00810 ADP-glucose pyrophosphorylase signature 3. 202 212 - T 22-04-2016 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|UniPathway: UPA00164 L21SP4_RS07365 e2e6dca881e05a963a773820ebfe176f 414 PANTHER PTHR22572:SF119 7 414 1.7E-140 T 22-04-2016 L21SP4_RS07365 e2e6dca881e05a963a773820ebfe176f 414 SUPERFAMILY SSF51161 284 413 1.66E-17 T 22-04-2016 IPR011004 Trimeric LpxA-like L21SP4_RS07365 e2e6dca881e05a963a773820ebfe176f 414 ProSitePatterns PS00809 ADP-glucose pyrophosphorylase signature 2. 98 106 - T 22-04-2016 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|UniPathway: UPA00164 L21SP4_RS07365 e2e6dca881e05a963a773820ebfe176f 414 SUPERFAMILY SSF53448 362 379 1.67E-73 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases L21SP4_RS07365 e2e6dca881e05a963a773820ebfe176f 414 SUPERFAMILY SSF53448 6 269 1.67E-73 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases L21SP4_RS07365 e2e6dca881e05a963a773820ebfe176f 414 Gene3D G3DSA:2.160.10.10 369 413 2.2E-4 T 22-04-2016 L21SP4_RS07365 e2e6dca881e05a963a773820ebfe176f 414 Gene3D G3DSA:3.90.550.10 8 326 2.8E-72 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases L21SP4_RS07365 e2e6dca881e05a963a773820ebfe176f 414 PANTHER PTHR22572 7 414 1.7E-140 T 22-04-2016 L21SP4_RS07365 e2e6dca881e05a963a773820ebfe176f 414 TIGRFAM TIGR02091 glgC: glucose-1-phosphate adenylyltransferase 7 380 8.4E-134 T 22-04-2016 IPR011831 Glucose-1-phosphate adenylyltransferase GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|UniPathway: UPA00164 L21SP4_RS04635 0b6b7696627c2c66820e28b25a56a3be 653 Gene3D G3DSA:1.50.10.10 126 215 3.0E-6 T 22-04-2016 IPR012341 Six-hairpin glycosidase GO:0003824 L21SP4_RS04635 0b6b7696627c2c66820e28b25a56a3be 653 Pfam PF07944 Beta-L-arabinofuranosidase, GH127 31 525 4.8E-37 T 22-04-2016 IPR012878 Beta-L-arabinofuranosidase, GH127 KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18 L21SP4_RS04635 0b6b7696627c2c66820e28b25a56a3be 653 PANTHER PTHR31151 383 530 2.9E-14 T 22-04-2016 L21SP4_RS04635 0b6b7696627c2c66820e28b25a56a3be 653 PANTHER PTHR31151:SF4 383 530 2.9E-14 T 22-04-2016 L21SP4_RS04635 0b6b7696627c2c66820e28b25a56a3be 653 SUPERFAMILY SSF48208 62 282 2.27E-13 T 22-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP4_RS02965 675af58dc077cad01d104ef17966c630 653 Pfam PF14508 Glycosyl-hydrolase 97 N-terminal 49 288 2.8E-42 T 22-04-2016 IPR029486 Glycosyl-hydrolase 97, N-terminal domain L21SP4_RS02965 675af58dc077cad01d104ef17966c630 653 SUPERFAMILY SSF51445 323 383 5.9E-5 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily L21SP4_RS02965 675af58dc077cad01d104ef17966c630 653 PANTHER PTHR35803 47 653 4.6E-92 T 22-04-2016 L21SP4_RS02965 675af58dc077cad01d104ef17966c630 653 Pfam PF14509 Glycosyl-hydrolase 97 C-terminal, oligomerisation 556 650 5.1E-15 T 22-04-2016 IPR029483 Glycosyl-hydrolase 97, C-terminal oligomerisation domain L21SP4_RS02965 675af58dc077cad01d104ef17966c630 653 Pfam PF10566 Glycoside hydrolase 97 304 553 3.4E-33 T 22-04-2016 IPR019563 Glycosyl-hydrolase 97, catalytic domain L21SP4_RS08240 aab93eeabd13e96d118828f076dbfe81 573 PANTHER PTHR30258:SF1 9 566 5.5E-174 T 22-04-2016 L21SP4_RS08240 aab93eeabd13e96d118828f076dbfe81 573 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 57 157 3.2E-13 T 22-04-2016 IPR007831 General secretory system II, protein E, N-terminal GO:0005524|GO:0006810 L21SP4_RS08240 aab93eeabd13e96d118828f076dbfe81 573 SMART SM00382 317 440 1.4E-4 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS08240 aab93eeabd13e96d118828f076dbfe81 573 SUPERFAMILY SSF52540 184 565 1.92E-97 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS08240 aab93eeabd13e96d118828f076dbfe81 573 Pfam PF00437 Type II/IV secretion system protein 192 456 7.7E-75 T 22-04-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 L21SP4_RS08240 aab93eeabd13e96d118828f076dbfe81 573 PANTHER PTHR30258 9 566 5.5E-174 T 22-04-2016 L21SP4_RS08240 aab93eeabd13e96d118828f076dbfe81 573 SUPERFAMILY SSF160246 20 157 2.62E-23 T 22-04-2016 L21SP4_RS08240 aab93eeabd13e96d118828f076dbfe81 573 Gene3D G3DSA:3.40.50.300 293 567 7.8E-98 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS08240 aab93eeabd13e96d118828f076dbfe81 573 Gene3D G3DSA:3.30.450.90 176 289 7.3E-38 T 22-04-2016 L21SP4_RS08240 aab93eeabd13e96d118828f076dbfe81 573 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 384 398 - T 22-04-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 L21SP4_RS10075 0aac6ea4d06b81569b060a5b1d2704be 290 Hamap MF_02040 Iron-sulfur cluster carrier protein. 32 283 36.006 T 22-04-2016 IPR019591 Mrp/NBP35 ATP-binding protein L21SP4_RS10075 0aac6ea4d06b81569b060a5b1d2704be 290 PANTHER PTHR23264 5 286 1.3E-132 T 22-04-2016 IPR019591 Mrp/NBP35 ATP-binding protein L21SP4_RS10075 0aac6ea4d06b81569b060a5b1d2704be 290 Gene3D G3DSA:3.40.50.300 30 280 3.6E-97 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS10075 0aac6ea4d06b81569b060a5b1d2704be 290 SUPERFAMILY SSF52540 25 259 1.1E-55 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS10075 0aac6ea4d06b81569b060a5b1d2704be 290 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 37 281 9.6E-93 T 22-04-2016 IPR019591 Mrp/NBP35 ATP-binding protein L21SP4_RS01380 02f42e3e9ea888e4887561ccb24a2163 553 PRINTS PR00811 Bacterial general secretion pathway protein D signature 228 238 1.3E-9 T 22-04-2016 IPR001775 GspD/PilQ family L21SP4_RS01380 02f42e3e9ea888e4887561ccb24a2163 553 PRINTS PR00811 Bacterial general secretion pathway protein D signature 298 322 1.3E-9 T 22-04-2016 IPR001775 GspD/PilQ family L21SP4_RS01380 02f42e3e9ea888e4887561ccb24a2163 553 PRINTS PR00811 Bacterial general secretion pathway protein D signature 449 467 1.3E-9 T 22-04-2016 IPR001775 GspD/PilQ family L21SP4_RS01380 02f42e3e9ea888e4887561ccb24a2163 553 PANTHER PTHR30332 171 548 1.3E-44 T 22-04-2016 L21SP4_RS01380 02f42e3e9ea888e4887561ccb24a2163 553 Pfam PF00263 Bacterial type II and III secretion system protein 302 483 5.4E-31 T 22-04-2016 IPR004846 Type II/III secretion system GO:0009306 L21SP4_RS01380 02f42e3e9ea888e4887561ccb24a2163 553 Pfam PF03958 Bacterial type II/III secretion system short domain 168 228 1.3E-8 T 22-04-2016 IPR005644 NolW-like L21SP4_RS08350 3cd49bec03c397ce9f85c038c3ca367d 78 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 6 77 2.4E-25 T 22-04-2016 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS08350 3cd49bec03c397ce9f85c038c3ca367d 78 Pfam PF00467 KOW motif 9 40 2.7E-8 T 22-04-2016 IPR005824 KOW L21SP4_RS08350 3cd49bec03c397ce9f85c038c3ca367d 78 Gene3D G3DSA:2.30.30.30 4 76 1.2E-21 T 22-04-2016 IPR014722 Ribosomal protein L2 domain 2 L21SP4_RS08350 3cd49bec03c397ce9f85c038c3ca367d 78 PANTHER PTHR12903 6 75 9.8E-27 T 22-04-2016 L21SP4_RS08350 3cd49bec03c397ce9f85c038c3ca367d 78 SUPERFAMILY SSF50104 5 76 6.62E-25 T 22-04-2016 IPR008991 Translation protein SH3-like domain L21SP4_RS08350 3cd49bec03c397ce9f85c038c3ca367d 78 SMART SM00739 6 33 1.7E-6 T 22-04-2016 IPR005824 KOW L21SP4_RS08350 3cd49bec03c397ce9f85c038c3ca367d 78 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 5 78 16.59 T 22-04-2016 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS08350 3cd49bec03c397ce9f85c038c3ca367d 78 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 42 77 4.4E-12 T 22-04-2016 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS08070 9260a2ee716b5ebe8e4566db25946059 185 Pfam PF13689 Domain of unknown function (DUF4154) 37 180 2.8E-40 T 22-04-2016 IPR025293 Protein of unknown function DUF4154 L21SP4_RS00850 848e78eb465f760ffd45d9a56e235d4f 72 Pfam PF10049 Protein of unknown function (DUF2283) 2 50 3.5E-15 T 22-04-2016 IPR019270 Protein of unknown function DUF2283 L21SP4_RS00850 848e78eb465f760ffd45d9a56e235d4f 72 PANTHER PTHR37029:SF1 1 68 2.6E-12 T 22-04-2016 L21SP4_RS00850 848e78eb465f760ffd45d9a56e235d4f 72 PANTHER PTHR37029 1 68 2.6E-12 T 22-04-2016 L21SP4_RS06635 99f5f89d2b6236ef85f3b15e46ffd2a0 776 Pfam PF03636 Glycosyl hydrolase family 65, N-terminal domain 10 245 2.0E-42 T 22-04-2016 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 L21SP4_RS06635 99f5f89d2b6236ef85f3b15e46ffd2a0 776 Gene3D G3DSA:2.60.420.10 693 752 5.7E-15 T 22-04-2016 L21SP4_RS06635 99f5f89d2b6236ef85f3b15e46ffd2a0 776 Pfam PF03632 Glycosyl hydrolase family 65 central catalytic domain 305 704 1.4E-91 T 22-04-2016 IPR005195 Glycoside hydrolase, family 65, central catalytic GO:0003824|GO:0005975 L21SP4_RS06635 99f5f89d2b6236ef85f3b15e46ffd2a0 776 Gene3D G3DSA:1.50.10.10 300 692 4.5E-95 T 22-04-2016 IPR012341 Six-hairpin glycosidase GO:0003824 L21SP4_RS06635 99f5f89d2b6236ef85f3b15e46ffd2a0 776 PANTHER PTHR11051 599 760 2.1E-109 T 22-04-2016 L21SP4_RS06635 99f5f89d2b6236ef85f3b15e46ffd2a0 776 PANTHER PTHR11051 1 581 2.1E-109 T 22-04-2016 L21SP4_RS06635 99f5f89d2b6236ef85f3b15e46ffd2a0 776 Gene3D G3DSA:2.70.98.40 2 249 4.0E-49 T 22-04-2016 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 L21SP4_RS06635 99f5f89d2b6236ef85f3b15e46ffd2a0 776 PIRSF PIRSF036289 1 765 2.0E-165 T 22-04-2016 IPR017045 Maltose phosphorylase/glycosyl hydrolase/vacuolar acid trehalase L21SP4_RS06635 99f5f89d2b6236ef85f3b15e46ffd2a0 776 Pfam PF03633 Glycosyl hydrolase family 65, C-terminal domain 710 747 3.9E-8 T 22-04-2016 IPR005194 Glycoside hydrolase family 65, C-terminal L21SP4_RS06635 99f5f89d2b6236ef85f3b15e46ffd2a0 776 SUPERFAMILY SSF74650 2 246 1.26E-40 T 22-04-2016 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 L21SP4_RS06635 99f5f89d2b6236ef85f3b15e46ffd2a0 776 SUPERFAMILY SSF48208 263 755 1.09E-91 T 22-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP4_RS05920 bb33f170f909802ea2797be8df641f07 649 SUPERFAMILY SSF158682 555 634 1.44E-5 T 22-04-2016 IPR029024 TerB-like L21SP4_RS05920 bb33f170f909802ea2797be8df641f07 649 PANTHER PTHR10120:SF19 63 353 2.6E-48 T 22-04-2016 L21SP4_RS05920 bb33f170f909802ea2797be8df641f07 649 PANTHER PTHR10120 63 353 2.6E-48 T 22-04-2016 L21SP4_RS05920 bb33f170f909802ea2797be8df641f07 649 Gene3D G3DSA:3.30.2010.10 108 190 9.4E-24 T 22-04-2016 L21SP4_RS05920 bb33f170f909802ea2797be8df641f07 649 Pfam PF01435 Peptidase family M48 110 332 4.4E-29 T 22-04-2016 IPR001915 Peptidase M48 GO:0004222|GO:0006508 L21SP4_RS05920 bb33f170f909802ea2797be8df641f07 649 Gene3D G3DSA:1.10.3680.10 567 634 7.8E-6 T 22-04-2016 IPR029024 TerB-like L21SP4_RS00925 8bc0780efb0a10689e050ff3032825fc 739 Gene3D G3DSA:3.90.182.10 230 323 1.6E-7 T 22-04-2016 IPR011658 PA14 domain L21SP4_RS00925 8bc0780efb0a10689e050ff3032825fc 739 Gene3D G3DSA:1.25.40.10 494 557 1.8E-8 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS00925 8bc0780efb0a10689e050ff3032825fc 739 Gene3D G3DSA:1.25.40.10 623 731 1.8E-8 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS00925 8bc0780efb0a10689e050ff3032825fc 739 SUPERFAMILY SSF48452 513 570 2.15E-5 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS00925 8bc0780efb0a10689e050ff3032825fc 739 SUPERFAMILY SSF48452 687 731 2.15E-5 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS00925 8bc0780efb0a10689e050ff3032825fc 739 Gene3D G3DSA:2.60.40.670 377 410 1.1E-4 T 22-04-2016 IPR000601 PKD domain L21SP4_RS10680 a60379d50a885c6d982d933c21bac986 180 SUPERFAMILY SSF52091 16 112 1.37E-13 T 22-04-2016 IPR002645 STAS domain L21SP4_RS10680 a60379d50a885c6d982d933c21bac986 180 Pfam PF01740 STAS domain 23 107 2.8E-9 T 22-04-2016 IPR002645 STAS domain L21SP4_RS10680 a60379d50a885c6d982d933c21bac986 180 Gene3D G3DSA:3.30.750.24 17 110 1.0E-16 T 22-04-2016 IPR002645 STAS domain L21SP4_RS08660 3c33715642053bf1e7a997a09fddfda8 346 PANTHER PTHR30544 2 343 3.6E-136 T 22-04-2016 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 L21SP4_RS08660 3c33715642053bf1e7a997a09fddfda8 346 PIRSF PIRSF006004 1 346 1.3E-115 T 22-04-2016 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 L21SP4_RS08660 3c33715642053bf1e7a997a09fddfda8 346 PANTHER PTHR30544:SF5 2 343 3.6E-136 T 22-04-2016 L21SP4_RS08660 3c33715642053bf1e7a997a09fddfda8 346 Gene3D G3DSA:3.20.20.70 103 320 1.3E-10 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP4_RS08660 3c33715642053bf1e7a997a09fddfda8 346 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 2 346 64.301 T 22-04-2016 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 L21SP4_RS08660 3c33715642053bf1e7a997a09fddfda8 346 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 2 344 5.7E-105 T 22-04-2016 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 L21SP4_RS08660 3c33715642053bf1e7a997a09fddfda8 346 Pfam PF04055 Radical SAM superfamily 107 270 6.1E-14 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 L21SP4_RS08660 3c33715642053bf1e7a997a09fddfda8 346 SUPERFAMILY SSF102114 99 312 1.44E-12 T 22-04-2016 L21SP4_RS06755 482355c469307cc2e24854fb3bb99868 450 Hamap MF_00661 ATP-dependent RNA helicase RhlB [rhlB]. 70 450 50.012 T 22-04-2016 IPR023554 ATP-dependent RNA helicase RhlB type GO:0004004 L21SP4_RS06755 482355c469307cc2e24854fb3bb99868 450 SUPERFAMILY SSF52540 147 433 1.59E-73 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS06755 482355c469307cc2e24854fb3bb99868 450 Pfam PF00270 DEAD/DEAH box helicase 95 269 6.4E-49 T 22-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 L21SP4_RS06755 482355c469307cc2e24854fb3bb99868 450 Gene3D G3DSA:3.40.50.300 63 285 3.1E-78 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS06755 482355c469307cc2e24854fb3bb99868 450 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 225 233 - T 22-04-2016 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site L21SP4_RS06755 482355c469307cc2e24854fb3bb99868 450 SMART SM00487 90 296 3.6E-52 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain L21SP4_RS06755 482355c469307cc2e24854fb3bb99868 450 Gene3D G3DSA:3.40.50.300 286 442 7.2E-52 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS06755 482355c469307cc2e24854fb3bb99868 450 PANTHER PTHR24031 15 438 8.3E-159 T 22-04-2016 L21SP4_RS06755 482355c469307cc2e24854fb3bb99868 450 Pfam PF00271 Helicase conserved C-terminal domain 305 413 1.7E-28 T 22-04-2016 IPR001650 Helicase, C-terminal L21SP4_RS06755 482355c469307cc2e24854fb3bb99868 450 SMART SM00490 332 413 1.8E-32 T 22-04-2016 IPR001650 Helicase, C-terminal L21SP4_RS03235 d7bf1a87917d6f1c719e4ca687e82e8a 819 PANTHER PTHR30408 107 448 5.6E-95 T 22-04-2016 L21SP4_RS03235 d7bf1a87917d6f1c719e4ca687e82e8a 819 Pfam PF12161 HsdM N-terminal domain 10 118 4.1E-17 T 22-04-2016 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain L21SP4_RS03235 d7bf1a87917d6f1c719e4ca687e82e8a 819 PANTHER PTHR30408:SF4 107 448 5.6E-95 T 22-04-2016 L21SP4_RS03235 d7bf1a87917d6f1c719e4ca687e82e8a 819 Pfam PF02384 N-6 DNA Methylase 131 442 1.1E-99 T 22-04-2016 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 L21SP4_RS03235 d7bf1a87917d6f1c719e4ca687e82e8a 819 Gene3D G3DSA:3.40.50.150 133 347 3.0E-35 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS03235 d7bf1a87917d6f1c719e4ca687e82e8a 819 SUPERFAMILY SSF53335 6 479 3.87E-122 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS03235 d7bf1a87917d6f1c719e4ca687e82e8a 819 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 154 170 2.6E-20 T 22-04-2016 L21SP4_RS03235 d7bf1a87917d6f1c719e4ca687e82e8a 819 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 291 315 2.6E-20 T 22-04-2016 L21SP4_RS03235 d7bf1a87917d6f1c719e4ca687e82e8a 819 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 182 196 2.6E-20 T 22-04-2016 L21SP4_RS03235 d7bf1a87917d6f1c719e4ca687e82e8a 819 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 254 266 2.6E-20 T 22-04-2016 L21SP4_RS00690 489a6d4c938a927c388e4c773cc047b0 1519 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 684 723 2.2E-4 T 22-04-2016 IPR006530 YD repeat L21SP4_RS00690 489a6d4c938a927c388e4c773cc047b0 1519 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1273 1365 5.5E-19 T 22-04-2016 IPR022385 Rhs repeat-associated core GO:0097264 L21SP4_RS00690 489a6d4c938a927c388e4c773cc047b0 1519 PANTHER PTHR11219 1239 1365 6.2E-13 T 22-04-2016 L21SP4_RS06380 53147c39bb4f0b25281c2e58c8089eb5 126 SMART SM00448 2 117 3.6E-16 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 L21SP4_RS06380 53147c39bb4f0b25281c2e58c8089eb5 126 PANTHER PTHR26402:SF578 2 121 2.6E-22 T 22-04-2016 L21SP4_RS06380 53147c39bb4f0b25281c2e58c8089eb5 126 Pfam PF00072 Response regulator receiver domain 4 118 2.1E-16 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 L21SP4_RS06380 53147c39bb4f0b25281c2e58c8089eb5 126 Gene3D G3DSA:3.40.50.2300 1 124 7.4E-26 T 22-04-2016 L21SP4_RS06380 53147c39bb4f0b25281c2e58c8089eb5 126 SUPERFAMILY SSF52172 1 122 3.98E-23 T 22-04-2016 IPR011006 CheY-like superfamily L21SP4_RS06380 53147c39bb4f0b25281c2e58c8089eb5 126 PANTHER PTHR26402 2 121 2.6E-22 T 22-04-2016 L21SP4_RS08975 b606addcabfa0db28362ce27882dc898 454 SUPERFAMILY SSF51735 33 199 7.29E-40 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS08975 b606addcabfa0db28362ce27882dc898 454 PANTHER PTHR22604 6 204 1.1E-81 T 22-04-2016 L21SP4_RS08975 b606addcabfa0db28362ce27882dc898 454 PANTHER PTHR22604 227 437 1.1E-81 T 22-04-2016 L21SP4_RS08975 b606addcabfa0db28362ce27882dc898 454 SUPERFAMILY SSF55347 227 383 5.89E-12 T 22-04-2016 L21SP4_RS08975 b606addcabfa0db28362ce27882dc898 454 SUPERFAMILY SSF55347 176 199 5.89E-12 T 22-04-2016 L21SP4_RS08975 b606addcabfa0db28362ce27882dc898 454 PANTHER PTHR22604:SF122 6 204 1.1E-81 T 22-04-2016 L21SP4_RS08975 b606addcabfa0db28362ce27882dc898 454 PANTHER PTHR22604:SF122 227 437 1.1E-81 T 22-04-2016 L21SP4_RS08975 b606addcabfa0db28362ce27882dc898 454 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 46 167 1.9E-12 T 22-04-2016 IPR000683 Oxidoreductase, N-terminal GO:0016491 L21SP4_RS08975 b606addcabfa0db28362ce27882dc898 454 Gene3D G3DSA:3.40.50.720 38 201 1.4E-42 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS08975 b606addcabfa0db28362ce27882dc898 454 Gene3D G3DSA:3.30.360.10 232 428 9.7E-16 T 22-04-2016 L21SP4_RS09045 3c3e1a10b0cba3503ab84f404b236c27 534 Gene3D G3DSA:3.20.20.70 3 351 4.0E-120 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP4_RS09045 3c3e1a10b0cba3503ab84f404b236c27 534 Pfam PF08502 LeuA allosteric (dimerisation) domain 379 519 1.3E-28 T 22-04-2016 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 L21SP4_RS09045 3c3e1a10b0cba3503ab84f404b236c27 534 SUPERFAMILY SSF110921 406 516 1.83E-22 T 22-04-2016 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 L21SP4_RS09045 3c3e1a10b0cba3503ab84f404b236c27 534 Pfam PF00682 HMGL-like 5 253 2.5E-46 T 22-04-2016 IPR000891 Pyruvate carboxyltransferase GO:0003824 L21SP4_RS09045 3c3e1a10b0cba3503ab84f404b236c27 534 TIGRFAM TIGR00977 citramal_synth: citramalate synthase 6 526 8.7E-220 T 22-04-2016 IPR005675 Citramalate synthase GO:0019752|GO:0046912 KEGG: 00290+2.3.1.182|KEGG: 00660+2.3.1.182|MetaCyc: PWY-5101|UniPathway: UPA00047 L21SP4_RS09045 3c3e1a10b0cba3503ab84f404b236c27 534 SMART SM00917 377 520 2.0E-40 T 22-04-2016 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 L21SP4_RS09045 3c3e1a10b0cba3503ab84f404b236c27 534 PANTHER PTHR10277 1 528 3.6E-255 T 22-04-2016 L21SP4_RS09045 3c3e1a10b0cba3503ab84f404b236c27 534 SUPERFAMILY SSF51569 3 295 2.75E-82 T 22-04-2016 L21SP4_RS09045 3c3e1a10b0cba3503ab84f404b236c27 534 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 13 29 - T 22-04-2016 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 L21SP4_RS09045 3c3e1a10b0cba3503ab84f404b236c27 534 PANTHER PTHR10277:SF5 1 528 3.6E-255 T 22-04-2016 IPR005675 Citramalate synthase GO:0019752|GO:0046912 KEGG: 00290+2.3.1.182|KEGG: 00660+2.3.1.182|MetaCyc: PWY-5101|UniPathway: UPA00047 L21SP4_RS03115 dd0fc9e6d4667f2085da457488c7b614 357 SUPERFAMILY SSF53756 64 350 1.36E-38 T 22-04-2016 L21SP4_RS03115 dd0fc9e6d4667f2085da457488c7b614 357 Gene3D G3DSA:3.40.50.2000 192 328 4.0E-12 T 22-04-2016 L21SP4_RS03115 dd0fc9e6d4667f2085da457488c7b614 357 Pfam PF00534 Glycosyl transferases group 1 183 329 1.8E-17 T 22-04-2016 IPR001296 Glycosyl transferase, family 1 L21SP4_RS03115 dd0fc9e6d4667f2085da457488c7b614 357 PANTHER PTHR12526:SF374 17 351 1.7E-29 T 22-04-2016 L21SP4_RS03115 dd0fc9e6d4667f2085da457488c7b614 357 PANTHER PTHR12526 17 351 1.7E-29 T 22-04-2016 L21SP4_RS03600 8a86f039a7083c3b4f002a6a7d2b67af 255 PANTHER PTHR30188 1 254 1.5E-85 T 22-04-2016 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 L21SP4_RS03600 8a86f039a7083c3b4f002a6a7d2b67af 255 TIGRFAM TIGR00056 TIGR00056: ABC transport permease subunit 17 254 2.7E-66 T 22-04-2016 IPR003453 ABC transport permease subunit MlaE, Proteobacteria L21SP4_RS03600 8a86f039a7083c3b4f002a6a7d2b67af 255 PANTHER PTHR30188:SF4 1 254 1.5E-85 T 22-04-2016 L21SP4_RS03600 8a86f039a7083c3b4f002a6a7d2b67af 255 Pfam PF02405 Permease MlaE 41 251 2.8E-71 T 22-04-2016 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 L21SP4_RS06975 4f5c573dc85ecc63834bab79c591d7bc 429 PANTHER PTHR10342:SF199 1 420 4.2E-75 T 22-04-2016 L21SP4_RS06975 4f5c573dc85ecc63834bab79c591d7bc 429 Pfam PF00884 Sulfatase 25 296 3.5E-40 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS06975 4f5c573dc85ecc63834bab79c591d7bc 429 Gene3D G3DSA:3.30.1120.10 323 407 2.8E-15 T 22-04-2016 L21SP4_RS06975 4f5c573dc85ecc63834bab79c591d7bc 429 PANTHER PTHR10342 1 420 4.2E-75 T 22-04-2016 L21SP4_RS06975 4f5c573dc85ecc63834bab79c591d7bc 429 Gene3D G3DSA:3.40.720.10 1 315 2.7E-57 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS06975 4f5c573dc85ecc63834bab79c591d7bc 429 SUPERFAMILY SSF53649 21 401 2.91E-79 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS00335 2ae5a0b39ad35b1366244d4418751c25 807 SUPERFAMILY SSF54211 575 768 3.79E-36 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold L21SP4_RS00335 2ae5a0b39ad35b1366244d4418751c25 807 SUPERFAMILY SSF52540 32 106 1.5E-14 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS00335 2ae5a0b39ad35b1366244d4418751c25 807 PANTHER PTHR10046 90 771 9.8E-123 T 22-04-2016 IPR027065 Lon protease GO:0004176|GO:0004252|GO:0005524|GO:0030163 L21SP4_RS00335 2ae5a0b39ad35b1366244d4418751c25 807 PANTHER PTHR10046:SF46 90 771 9.8E-123 T 22-04-2016 L21SP4_RS00335 2ae5a0b39ad35b1366244d4418751c25 807 Pfam PF13654 AAA domain 27 550 3.0E-200 T 22-04-2016 L21SP4_RS00335 2ae5a0b39ad35b1366244d4418751c25 807 SUPERFAMILY SSF52540 24 275 1.06E-7 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS00335 2ae5a0b39ad35b1366244d4418751c25 807 SUPERFAMILY SSF52540 317 570 1.5E-14 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS00335 2ae5a0b39ad35b1366244d4418751c25 807 Gene3D G3DSA:3.30.230.10 568 766 2.8E-29 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup L21SP4_RS00335 2ae5a0b39ad35b1366244d4418751c25 807 Gene3D G3DSA:3.40.50.300 38 228 5.9E-7 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS00335 2ae5a0b39ad35b1366244d4418751c25 807 Gene3D G3DSA:3.40.50.300 429 449 5.9E-7 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS00335 2ae5a0b39ad35b1366244d4418751c25 807 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 660 762 2.8E-10 T 22-04-2016 IPR008269 Peptidase S16, Lon C-terminal GO:0004176|GO:0004252|GO:0006508 L21SP4_RS00335 2ae5a0b39ad35b1366244d4418751c25 807 Gene3D G3DSA:3.40.50.300 355 428 8.2E-4 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS00335 2ae5a0b39ad35b1366244d4418751c25 807 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 657 676 8.6E-14 T 22-04-2016 L21SP4_RS00335 2ae5a0b39ad35b1366244d4418751c25 807 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 687 706 8.6E-14 T 22-04-2016 L21SP4_RS00335 2ae5a0b39ad35b1366244d4418751c25 807 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 576 592 8.6E-14 T 22-04-2016 L21SP4_RS00335 2ae5a0b39ad35b1366244d4418751c25 807 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 63 82 8.6E-14 T 22-04-2016 L21SP4_RS00335 2ae5a0b39ad35b1366244d4418751c25 807 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 717 735 8.6E-14 T 22-04-2016 L21SP4_RS02590 4a021cc200a3f317bfc0bbacfd4fefec 210 Pfam PF05991 YacP-like NYN domain 39 138 3.8E-7 T 22-04-2016 IPR010298 Protein of unknown function DUF901 L21SP4_RS07470 b066113f02c3e34f30beb7799740a89e 877 Gene3D G3DSA:3.40.1140.10 796 859 2.7E-11 T 22-04-2016 L21SP4_RS07470 b066113f02c3e34f30beb7799740a89e 877 Gene3D G3DSA:3.40.1140.10 104 105 2.7E-11 T 22-04-2016 L21SP4_RS07470 b066113f02c3e34f30beb7799740a89e 877 Gene3D G3DSA:3.40.1140.10 1 70 2.7E-11 T 22-04-2016 L21SP4_RS07470 b066113f02c3e34f30beb7799740a89e 877 Pfam PF13175 AAA ATPase domain 1 337 5.8E-9 T 22-04-2016 L21SP4_RS07470 b066113f02c3e34f30beb7799740a89e 877 SUPERFAMILY SSF52540 696 863 4.6E-11 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS07470 b066113f02c3e34f30beb7799740a89e 877 SUPERFAMILY SSF52540 1 52 4.6E-11 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS12075 1e861cb491adaee14671c4c64599710a 450 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 59 166 5.4E-16 T 22-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 L21SP4_RS12075 1e861cb491adaee14671c4c64599710a 450 Gene3D G3DSA:1.10.8.60 196 233 2.0E-7 T 22-04-2016 L21SP4_RS12075 1e861cb491adaee14671c4c64599710a 450 Pfam PF12002 MgsA AAA+ ATPase C terminal 274 435 5.0E-67 T 22-04-2016 IPR021886 MgsA AAA+ ATPase C-terminal L21SP4_RS12075 1e861cb491adaee14671c4c64599710a 450 PANTHER PTHR13779 11 439 1.2E-180 T 22-04-2016 L21SP4_RS12075 1e861cb491adaee14671c4c64599710a 450 Gene3D G3DSA:3.40.50.300 19 171 1.5E-30 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS12075 1e861cb491adaee14671c4c64599710a 450 Gene3D G3DSA:1.20.272.10 255 353 9.0E-44 T 22-04-2016 L21SP4_RS12075 1e861cb491adaee14671c4c64599710a 450 Gene3D G3DSA:1.10.3710.10 354 445 1.2E-24 T 22-04-2016 L21SP4_RS12075 1e861cb491adaee14671c4c64599710a 450 SUPERFAMILY SSF48019 259 439 1.76E-69 T 22-04-2016 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: REACT_152|Reactome: REACT_1538|Reactome: REACT_216|Reactome: REACT_22172|Reactome: REACT_383 L21SP4_RS12075 1e861cb491adaee14671c4c64599710a 450 PANTHER PTHR13779:SF32 11 439 1.2E-180 T 22-04-2016 L21SP4_RS12075 1e861cb491adaee14671c4c64599710a 450 Pfam PF16193 AAA C-terminal domain 195 273 3.9E-26 T 22-04-2016 IPR032423 AAA ATPase, C-terminal domain L21SP4_RS12075 1e861cb491adaee14671c4c64599710a 450 SUPERFAMILY SSF52540 17 229 3.77E-43 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS12075 1e861cb491adaee14671c4c64599710a 450 SMART SM00382 55 172 2.3E-14 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS09950 f7e9f91d4273700b32806934bd969c6e 352 Gene3D G3DSA:3.20.20.210 83 349 1.1E-24 T 22-04-2016 L21SP4_RS09950 f7e9f91d4273700b32806934bd969c6e 352 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 92 348 8.9E-20 T 22-04-2016 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 L21SP4_RS09950 f7e9f91d4273700b32806934bd969c6e 352 SUPERFAMILY SSF51726 64 349 7.5E-23 T 22-04-2016 L21SP4_RS01510 b358a61e109846fe91d0f099eb662f37 311 SUPERFAMILY SSF101960 56 309 3.79E-40 T 22-04-2016 L21SP4_RS01510 b358a61e109846fe91d0f099eb662f37 311 PANTHER PTHR30508:SF5 59 309 2.9E-56 T 22-04-2016 L21SP4_RS01510 b358a61e109846fe91d0f099eb662f37 311 PANTHER PTHR30508 59 309 2.9E-56 T 22-04-2016 L21SP4_RS01510 b358a61e109846fe91d0f099eb662f37 311 Pfam PF01458 Uncharacterized protein family (UPF0051) 88 307 3.1E-29 T 22-04-2016 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 L21SP4_RS11405 976d3aed11699eeed518e225a1156b3d 943 SUPERFAMILY SSF48208 534 924 4.18E-43 T 22-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP4_RS11405 976d3aed11699eeed518e225a1156b3d 943 Gene3D G3DSA:2.60.120.260 9 93 1.8E-9 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS11405 976d3aed11699eeed518e225a1156b3d 943 Pfam PF08531 Alpha-L-rhamnosidase N-terminal domain 35 135 2.6E-8 T 22-04-2016 IPR013737 Bacterial alpha-L-rhamnosidase N-terminal L21SP4_RS11405 976d3aed11699eeed518e225a1156b3d 943 SUPERFAMILY SSF49785 15 93 3.26E-8 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS11405 976d3aed11699eeed518e225a1156b3d 943 PANTHER PTHR34987 497 921 2.0E-45 T 22-04-2016 L21SP4_RS11405 976d3aed11699eeed518e225a1156b3d 943 Pfam PF05592 Bacterial alpha-L-rhamnosidase 432 925 1.0E-62 T 22-04-2016 IPR008902 Bacterial alpha-L-rhamnosidase L21SP4_RS06500 9f17ca7a673f86a3a7ac485367d51140 304 Pfam PF00149 Calcineurin-like phosphoesterase 97 303 1.4E-14 T 22-04-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 L21SP4_RS06500 9f17ca7a673f86a3a7ac485367d51140 304 SUPERFAMILY SSF56300 94 303 1.97E-25 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like L21SP4_RS06500 9f17ca7a673f86a3a7ac485367d51140 304 Gene3D G3DSA:3.60.21.10 93 304 2.0E-16 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like L21SP4_RS05665 40484e30d43bd79375aa74b18adcbfc7 170 Pfam PF13710 ACT domain 21 82 1.1E-16 T 22-04-2016 L21SP4_RS05665 40484e30d43bd79375aa74b18adcbfc7 170 SUPERFAMILY SSF55021 12 85 1.19E-19 T 22-04-2016 L21SP4_RS05665 40484e30d43bd79375aa74b18adcbfc7 170 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 12 84 8.0E-17 T 22-04-2016 L21SP4_RS05665 40484e30d43bd79375aa74b18adcbfc7 170 Pfam PF10369 Small subunit of acetolactate synthase 93 166 2.9E-21 T 22-04-2016 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 L21SP4_RS05665 40484e30d43bd79375aa74b18adcbfc7 170 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 12 167 4.7E-45 T 22-04-2016 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 L21SP4_RS05665 40484e30d43bd79375aa74b18adcbfc7 170 Gene3D G3DSA:3.30.70.1150 93 167 4.7E-22 T 22-04-2016 L21SP4_RS05665 40484e30d43bd79375aa74b18adcbfc7 170 Gene3D G3DSA:3.30.70.260 11 86 1.0E-28 T 22-04-2016 L21SP4_RS05665 40484e30d43bd79375aa74b18adcbfc7 170 SUPERFAMILY SSF55021 89 167 3.05E-20 T 22-04-2016 L21SP4_RS05665 40484e30d43bd79375aa74b18adcbfc7 170 PANTHER PTHR30239 12 167 9.9E-53 T 22-04-2016 L21SP4_RS11150 63990ec3544386f2dab32d82cf135efe 77 SUPERFAMILY SSF47598 5 45 4.45E-5 T 22-04-2016 IPR010985 Ribbon-helix-helix GO:0006355 L21SP4_RS11150 63990ec3544386f2dab32d82cf135efe 77 Gene3D G3DSA:1.10.1220.10 4 45 3.1E-5 T 22-04-2016 IPR013321 Arc-type ribbon-helix-helix GO:0006355 L21SP4_RS09195 4de0c5021d000b710493416ef417c547 362 Gene3D G3DSA:3.40.50.300 53 94 3.7E-19 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS09195 4de0c5021d000b710493416ef417c547 362 Gene3D G3DSA:3.40.50.300 134 317 3.7E-19 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS09195 4de0c5021d000b710493416ef417c547 362 SUPERFAMILY SSF52540 128 227 8.73E-33 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS09195 4de0c5021d000b710493416ef417c547 362 SUPERFAMILY SSF52540 260 361 8.73E-33 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS09195 4de0c5021d000b710493416ef417c547 362 SUPERFAMILY SSF52540 53 100 8.73E-33 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS09195 4de0c5021d000b710493416ef417c547 362 Pfam PF13469 Sulfotransferase family 57 315 2.4E-21 T 22-04-2016 L21SP4_RS05595 c8830afe41002858918b8ddb39a5e4d4 444 PANTHER PTHR22604 1 212 5.3E-68 T 22-04-2016 L21SP4_RS05595 c8830afe41002858918b8ddb39a5e4d4 444 PANTHER PTHR22604 367 437 5.3E-68 T 22-04-2016 L21SP4_RS05595 c8830afe41002858918b8ddb39a5e4d4 444 PANTHER PTHR22604 231 338 5.3E-68 T 22-04-2016 L21SP4_RS05595 c8830afe41002858918b8ddb39a5e4d4 444 Gene3D G3DSA:3.40.50.720 39 171 2.0E-39 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS05595 c8830afe41002858918b8ddb39a5e4d4 444 PANTHER PTHR22604:SF122 1 212 5.3E-68 T 22-04-2016 L21SP4_RS05595 c8830afe41002858918b8ddb39a5e4d4 444 PANTHER PTHR22604:SF122 367 437 5.3E-68 T 22-04-2016 L21SP4_RS05595 c8830afe41002858918b8ddb39a5e4d4 444 PANTHER PTHR22604:SF122 231 338 5.3E-68 T 22-04-2016 L21SP4_RS05595 c8830afe41002858918b8ddb39a5e4d4 444 Gene3D G3DSA:3.30.360.10 172 343 3.6E-38 T 22-04-2016 L21SP4_RS05595 c8830afe41002858918b8ddb39a5e4d4 444 Gene3D G3DSA:3.30.360.10 389 433 3.6E-38 T 22-04-2016 L21SP4_RS05595 c8830afe41002858918b8ddb39a5e4d4 444 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 42 166 3.5E-20 T 22-04-2016 IPR000683 Oxidoreductase, N-terminal GO:0016491 L21SP4_RS05595 c8830afe41002858918b8ddb39a5e4d4 444 SUPERFAMILY SSF51735 38 181 2.74E-39 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS05595 c8830afe41002858918b8ddb39a5e4d4 444 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 220 286 4.7E-8 T 22-04-2016 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 L21SP4_RS05595 c8830afe41002858918b8ddb39a5e4d4 444 SUPERFAMILY SSF55347 223 341 4.09E-20 T 22-04-2016 L21SP4_RS11895 6c6a324d8ffd30432fe6605f0ff545f5 269 SUPERFAMILY SSF51730 28 200 2.75E-19 T 22-04-2016 IPR029041 FAD-linked oxidoreductase-like L21SP4_RS11895 6c6a324d8ffd30432fe6605f0ff545f5 269 Pfam PF02219 Methylenetetrahydrofolate reductase 76 181 6.1E-11 T 22-04-2016 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00193 L21SP4_RS11895 6c6a324d8ffd30432fe6605f0ff545f5 269 Gene3D G3DSA:3.20.20.220 39 192 7.5E-18 T 22-04-2016 IPR029041 FAD-linked oxidoreductase-like L21SP4_RS05705 0640fcabd28adae15d3e3e30fb8921cb 208 PANTHER PTHR30586 2 196 3.4E-65 T 22-04-2016 L21SP4_RS05705 0640fcabd28adae15d3e3e30fb8921cb 208 Pfam PF02508 Rnf-Nqr subunit, membrane protein 9 190 6.9E-57 T 22-04-2016 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 L21SP4_RS05705 0640fcabd28adae15d3e3e30fb8921cb 208 PIRSF PIRSF006102 6 207 4.1E-58 T 22-04-2016 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 L21SP4_RS05875 3397ddf37a36d4a16a46f508a8857f48 333 Gene3D G3DSA:3.40.50.300 10 317 7.6E-22 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS05875 3397ddf37a36d4a16a46f508a8857f48 333 Pfam PF13469 Sulfotransferase family 14 212 5.1E-9 T 22-04-2016 L21SP4_RS05875 3397ddf37a36d4a16a46f508a8857f48 333 SUPERFAMILY SSF52540 279 322 9.11E-21 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS05875 3397ddf37a36d4a16a46f508a8857f48 333 SUPERFAMILY SSF52540 12 245 9.11E-21 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS06105 feedfdd875f97b49fc31c05d37664fcc 538 Pfam PF00072 Response regulator receiver domain 14 125 2.2E-29 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 L21SP4_RS06105 feedfdd875f97b49fc31c05d37664fcc 538 SMART SM00448 12 125 1.2E-41 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 L21SP4_RS06105 feedfdd875f97b49fc31c05d37664fcc 538 Gene3D G3DSA:3.40.50.2300 13 138 2.5E-40 T 22-04-2016 L21SP4_RS06105 feedfdd875f97b49fc31c05d37664fcc 538 SUPERFAMILY SSF81606 181 394 1.06E-9 T 22-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 L21SP4_RS06105 feedfdd875f97b49fc31c05d37664fcc 538 PANTHER PTHR26402 12 151 6.9E-43 T 22-04-2016 L21SP4_RS06105 feedfdd875f97b49fc31c05d37664fcc 538 Pfam PF13581 Histidine kinase-like ATPase domain 409 517 9.9E-12 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS06105 feedfdd875f97b49fc31c05d37664fcc 538 SMART SM00331 167 395 4.1E-13 T 22-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 L21SP4_RS06105 feedfdd875f97b49fc31c05d37664fcc 538 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 193 394 7.0E-32 T 22-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 L21SP4_RS06105 feedfdd875f97b49fc31c05d37664fcc 538 SUPERFAMILY SSF52172 13 149 1.42E-41 T 22-04-2016 IPR011006 CheY-like superfamily L21SP4_RS02560 09358a7d238a147f1889ded2eaf95fa5 528 SUPERFAMILY SSF53649 461 503 1.22E-84 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS02560 09358a7d238a147f1889ded2eaf95fa5 528 SUPERFAMILY SSF53649 22 401 1.22E-84 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS02560 09358a7d238a147f1889ded2eaf95fa5 528 PANTHER PTHR10342 457 508 2.2E-83 T 22-04-2016 L21SP4_RS02560 09358a7d238a147f1889ded2eaf95fa5 528 PANTHER PTHR10342 1 356 2.2E-83 T 22-04-2016 L21SP4_RS02560 09358a7d238a147f1889ded2eaf95fa5 528 PANTHER PTHR10342 374 421 2.2E-83 T 22-04-2016 L21SP4_RS02560 09358a7d238a147f1889ded2eaf95fa5 528 Gene3D G3DSA:3.30.1120.10 463 511 4.7E-17 T 22-04-2016 L21SP4_RS02560 09358a7d238a147f1889ded2eaf95fa5 528 Gene3D G3DSA:3.30.1120.10 382 403 4.7E-17 T 22-04-2016 L21SP4_RS02560 09358a7d238a147f1889ded2eaf95fa5 528 Pfam PF00884 Sulfatase 23 336 1.0E-36 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS02560 09358a7d238a147f1889ded2eaf95fa5 528 Gene3D G3DSA:3.40.720.10 20 354 1.8E-64 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS06215 17ab1c2ffdf54802857e367a2062f338 373 SUPERFAMILY SSF53784 4 364 9.55E-111 T 22-04-2016 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 L21SP4_RS06215 17ab1c2ffdf54802857e367a2062f338 373 Gene3D G3DSA:3.40.50.450 3 220 2.9E-72 T 22-04-2016 L21SP4_RS06215 17ab1c2ffdf54802857e367a2062f338 373 PIRSF PIRSF000532 1 373 2.8E-115 T 22-04-2016 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|UniPathway: UPA00109 L21SP4_RS06215 17ab1c2ffdf54802857e367a2062f338 373 Hamap MF_01976 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase [pfp]. 3 372 41.073 T 22-04-2016 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|UniPathway: UPA00109 L21SP4_RS06215 17ab1c2ffdf54802857e367a2062f338 373 Pfam PF00365 Phosphofructokinase 5 322 5.8E-96 T 22-04-2016 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 L21SP4_RS06215 17ab1c2ffdf54802857e367a2062f338 373 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 101 117 5.1E-56 T 22-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 L21SP4_RS06215 17ab1c2ffdf54802857e367a2062f338 373 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 7 26 5.1E-56 T 22-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 L21SP4_RS06215 17ab1c2ffdf54802857e367a2062f338 373 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 166 182 5.1E-56 T 22-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 L21SP4_RS06215 17ab1c2ffdf54802857e367a2062f338 373 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 33 46 5.1E-56 T 22-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 L21SP4_RS06215 17ab1c2ffdf54802857e367a2062f338 373 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 220 232 5.1E-56 T 22-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 L21SP4_RS06215 17ab1c2ffdf54802857e367a2062f338 373 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 184 201 5.1E-56 T 22-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 L21SP4_RS06215 17ab1c2ffdf54802857e367a2062f338 373 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 128 145 5.1E-56 T 22-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 L21SP4_RS06215 17ab1c2ffdf54802857e367a2062f338 373 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 146 164 5.1E-56 T 22-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 L21SP4_RS06215 17ab1c2ffdf54802857e367a2062f338 373 ProSitePatterns PS00433 Phosphofructokinase signature. 291 309 - T 22-04-2016 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 L21SP4_RS06215 17ab1c2ffdf54802857e367a2062f338 373 PANTHER PTHR13697 4 239 1.4E-111 T 22-04-2016 L21SP4_RS06215 17ab1c2ffdf54802857e367a2062f338 373 PANTHER PTHR13697 276 360 1.4E-111 T 22-04-2016 L21SP4_RS02655 0d0660b020850551709a8f96d35cc3f8 233 Gene3D G3DSA:2.20.25.10 8 21 3.6E-4 T 22-04-2016 L21SP4_RS02655 0d0660b020850551709a8f96d35cc3f8 233 Pfam PF14353 CpXC protein 8 137 8.8E-23 T 22-04-2016 IPR025682 CpXC domain L21SP4_RS08490 6bcf860cd5499b770758e39c1a86c719 334 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 7 331 2.9E-115 T 22-04-2016 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18|UniPathway: UPA00035 L21SP4_RS08490 6bcf860cd5499b770758e39c1a86c719 334 SUPERFAMILY SSF47648 2 68 1.23E-14 T 22-04-2016 IPR017459 Glycosyl transferase family 3, N-terminal domain L21SP4_RS08490 6bcf860cd5499b770758e39c1a86c719 334 Gene3D G3DSA:3.40.1030.10 74 334 6.3E-103 T 22-04-2016 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 L21SP4_RS08490 6bcf860cd5499b770758e39c1a86c719 334 Pfam PF02885 Glycosyl transferase family, helical bundle domain 4 65 3.6E-16 T 22-04-2016 IPR017459 Glycosyl transferase family 3, N-terminal domain L21SP4_RS08490 6bcf860cd5499b770758e39c1a86c719 334 SUPERFAMILY SSF52418 73 333 3.66E-93 T 22-04-2016 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 L21SP4_RS08490 6bcf860cd5499b770758e39c1a86c719 334 Pfam PF00591 Glycosyl transferase family, a/b domain 74 323 1.3E-89 T 22-04-2016 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 L21SP4_RS08490 6bcf860cd5499b770758e39c1a86c719 334 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 4 333 36.302 T 22-04-2016 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18|UniPathway: UPA00035 L21SP4_RS08490 6bcf860cd5499b770758e39c1a86c719 334 Gene3D G3DSA:1.20.970.10 1 65 1.3E-17 T 22-04-2016 L21SP4_RS08490 6bcf860cd5499b770758e39c1a86c719 334 PANTHER PTHR11922:SF5 76 334 8.4E-114 T 22-04-2016 L21SP4_RS08490 6bcf860cd5499b770758e39c1a86c719 334 PANTHER PTHR11922 76 334 8.4E-114 T 22-04-2016 L21SP4_RS09120 9d3e7bd0fce5acfa41e6068cdee0ad90 247 Pfam PF01904 Protein of unknown function DUF72 27 243 3.0E-60 T 22-04-2016 IPR002763 Protein of unknown function DUF72 L21SP4_RS09120 9d3e7bd0fce5acfa41e6068cdee0ad90 247 SUPERFAMILY SSF117396 9 246 1.22E-78 T 22-04-2016 IPR002763 Protein of unknown function DUF72 L21SP4_RS09120 9d3e7bd0fce5acfa41e6068cdee0ad90 247 Gene3D G3DSA:3.20.20.410 8 246 4.7E-77 T 22-04-2016 IPR002763 Protein of unknown function DUF72 L21SP4_RS09120 9d3e7bd0fce5acfa41e6068cdee0ad90 247 PANTHER PTHR30348 1 246 1.7E-76 T 22-04-2016 L21SP4_RS04885 45c9ae8caf5376f96da13c46a3c731b6 367 Pfam PF13424 Tetratricopeptide repeat 196 258 1.2E-9 T 22-04-2016 L21SP4_RS04885 45c9ae8caf5376f96da13c46a3c731b6 367 Gene3D G3DSA:1.25.40.10 179 256 5.1E-22 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS04885 45c9ae8caf5376f96da13c46a3c731b6 367 SMART SM00028 127 160 0.4 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS04885 45c9ae8caf5376f96da13c46a3c731b6 367 SMART SM00028 195 228 0.012 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS04885 45c9ae8caf5376f96da13c46a3c731b6 367 SMART SM00028 229 262 2.5E-5 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS04885 45c9ae8caf5376f96da13c46a3c731b6 367 SMART SM00028 161 194 230.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS04885 45c9ae8caf5376f96da13c46a3c731b6 367 SMART SM00028 297 330 25.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS04885 45c9ae8caf5376f96da13c46a3c731b6 367 PANTHER PTHR23083 102 331 2.0E-33 T 22-04-2016 L21SP4_RS04885 45c9ae8caf5376f96da13c46a3c731b6 367 Pfam PF13176 Tetratricopeptide repeat 167 189 6.0E-4 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS04885 45c9ae8caf5376f96da13c46a3c731b6 367 Gene3D G3DSA:1.25.40.10 127 178 1.1E-8 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS04885 45c9ae8caf5376f96da13c46a3c731b6 367 Gene3D G3DSA:1.25.40.10 257 326 8.6E-10 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS04885 45c9ae8caf5376f96da13c46a3c731b6 367 SUPERFAMILY SSF48452 127 326 1.11E-31 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS01465 d58960d9c786b4cdaf42d1ff8424e4db 249 Pfam PF00005 ABC transporter 28 166 6.0E-29 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 L21SP4_RS01465 d58960d9c786b4cdaf42d1ff8424e4db 249 SUPERFAMILY SSF52540 17 210 2.39E-55 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS01465 d58960d9c786b4cdaf42d1ff8424e4db 249 SMART SM00382 36 214 9.6E-11 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS01465 d58960d9c786b4cdaf42d1ff8424e4db 249 Gene3D G3DSA:3.40.50.300 5 226 1.6E-59 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS01465 d58960d9c786b4cdaf42d1ff8424e4db 249 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 L21SP4_RS01465 d58960d9c786b4cdaf42d1ff8424e4db 249 PANTHER PTHR24220 13 243 5.8E-73 T 22-04-2016 L21SP4_RS03635 e52f0c823c443d4aa82880908f8c3575 187 SUPERFAMILY SSF55194 5 186 5.49E-67 T 22-04-2016 IPR023584 Ribosome recycling factor domain L21SP4_RS03635 e52f0c823c443d4aa82880908f8c3575 187 Pfam PF01765 Ribosome recycling factor 22 185 7.8E-60 T 22-04-2016 IPR023584 Ribosome recycling factor domain L21SP4_RS03635 e52f0c823c443d4aa82880908f8c3575 187 PANTHER PTHR20982 7 187 3.4E-71 T 22-04-2016 IPR002661 Ribosome recycling factor GO:0006412 L21SP4_RS03635 e52f0c823c443d4aa82880908f8c3575 187 Gene3D G3DSA:1.10.132.20 68 187 1.4E-39 T 22-04-2016 IPR023584 Ribosome recycling factor domain L21SP4_RS03635 e52f0c823c443d4aa82880908f8c3575 187 TIGRFAM TIGR00496 frr: ribosome recycling factor 13 187 6.0E-66 T 22-04-2016 IPR002661 Ribosome recycling factor GO:0006412 L21SP4_RS03635 e52f0c823c443d4aa82880908f8c3575 187 Hamap MF_00040 Ribosome-recycling factor [frr]. 5 187 26.23 T 22-04-2016 IPR002661 Ribosome recycling factor GO:0006412 L21SP4_RS06920 79c255cd3e349f5ecf342d2e0e0b9cf0 76 PANTHER PTHR12611 2 57 3.0E-12 T 22-04-2016 IPR006628 Purine-rich element binding protein family L21SP4_RS06920 79c255cd3e349f5ecf342d2e0e0b9cf0 76 SMART SM00712 4 65 8.8E-15 T 22-04-2016 IPR006628 Purine-rich element binding protein family L21SP4_RS06920 79c255cd3e349f5ecf342d2e0e0b9cf0 76 Pfam PF04845 PurA ssDNA and RNA-binding protein 3 65 2.1E-14 T 22-04-2016 IPR006628 Purine-rich element binding protein family L21SP4_RS06940 89aa3a856a78182e80a68e41e316741a 470 SUPERFAMILY SSF53067 154 429 1.8E-12 T 22-04-2016 L21SP4_RS06940 89aa3a856a78182e80a68e41e316741a 470 Gene3D G3DSA:3.30.420.40 290 436 8.1E-7 T 22-04-2016 L21SP4_RS06940 89aa3a856a78182e80a68e41e316741a 470 Gene3D G3DSA:3.30.420.40 153 289 3.0E-8 T 22-04-2016 L21SP4_RS10670 eb942d7124c5aa4345019f68c44502d2 203 SUPERFAMILY SSF51064 137 193 7.72E-18 T 22-04-2016 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 L21SP4_RS10670 eb942d7124c5aa4345019f68c44502d2 203 SUPERFAMILY SSF58014 46 136 7.06E-24 T 22-04-2016 L21SP4_RS10670 eb942d7124c5aa4345019f68c44502d2 203 PRINTS PR00773 GrpE protein signature 62 78 1.5E-25 T 22-04-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 L21SP4_RS10670 eb942d7124c5aa4345019f68c44502d2 203 PRINTS PR00773 GrpE protein signature 144 159 1.5E-25 T 22-04-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 L21SP4_RS10670 eb942d7124c5aa4345019f68c44502d2 203 PRINTS PR00773 GrpE protein signature 90 105 1.5E-25 T 22-04-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 L21SP4_RS10670 eb942d7124c5aa4345019f68c44502d2 203 PRINTS PR00773 GrpE protein signature 171 190 1.5E-25 T 22-04-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 L21SP4_RS10670 eb942d7124c5aa4345019f68c44502d2 203 ProSitePatterns PS01071 grpE protein signature. 147 190 - T 22-04-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 L21SP4_RS10670 eb942d7124c5aa4345019f68c44502d2 203 Gene3D G3DSA:2.30.22.10 136 194 7.0E-25 T 22-04-2016 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 L21SP4_RS10670 eb942d7124c5aa4345019f68c44502d2 203 Hamap MF_01151 Protein GrpE [grpE]. 13 192 20.199 T 22-04-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 L21SP4_RS10670 eb942d7124c5aa4345019f68c44502d2 203 PANTHER PTHR21237 21 195 8.0E-57 T 22-04-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 L21SP4_RS10670 eb942d7124c5aa4345019f68c44502d2 203 Pfam PF01025 GrpE 8 191 3.8E-50 T 22-04-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 L21SP4_RS10670 eb942d7124c5aa4345019f68c44502d2 203 Gene3D G3DSA:3.90.20.20 42 135 2.3E-26 T 22-04-2016 IPR013805 GrpE nucleotide exchange factor, coiled-coil L21SP4_RS10315 392b898783fab938bcbf154553fc751a 398 Gene3D G3DSA:1.10.287.130 163 223 1.6E-7 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS10315 392b898783fab938bcbf154553fc751a 398 Pfam PF00512 His Kinase A (phospho-acceptor) domain 162 230 1.3E-9 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS10315 392b898783fab938bcbf154553fc751a 398 Pfam PF00072 Response regulator receiver domain 10 118 4.4E-30 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 L21SP4_RS10315 392b898783fab938bcbf154553fc751a 398 SMART SM00388 157 232 1.3E-4 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS10315 392b898783fab938bcbf154553fc751a 398 SUPERFAMILY SSF47384 154 232 7.06E-9 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS10315 392b898783fab938bcbf154553fc751a 398 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 277 385 5.2E-22 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS10315 392b898783fab938bcbf154553fc751a 398 PANTHER PTHR24423 38 62 7.9E-50 T 22-04-2016 L21SP4_RS10315 392b898783fab938bcbf154553fc751a 398 PANTHER PTHR24423 130 388 7.9E-50 T 22-04-2016 L21SP4_RS10315 392b898783fab938bcbf154553fc751a 398 PRINTS PR00344 Bacterial sensor protein C-terminal signature 332 342 5.6E-18 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS10315 392b898783fab938bcbf154553fc751a 398 PRINTS PR00344 Bacterial sensor protein C-terminal signature 370 383 5.6E-18 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS10315 392b898783fab938bcbf154553fc751a 398 PRINTS PR00344 Bacterial sensor protein C-terminal signature 346 364 5.6E-18 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS10315 392b898783fab938bcbf154553fc751a 398 PRINTS PR00344 Bacterial sensor protein C-terminal signature 314 328 5.6E-18 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS10315 392b898783fab938bcbf154553fc751a 398 SUPERFAMILY SSF55874 232 389 6.42E-36 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS10315 392b898783fab938bcbf154553fc751a 398 SUPERFAMILY SSF52172 8 145 6.69E-38 T 22-04-2016 IPR011006 CheY-like superfamily L21SP4_RS10315 392b898783fab938bcbf154553fc751a 398 Gene3D G3DSA:3.40.50.2300 9 139 5.9E-38 T 22-04-2016 L21SP4_RS10315 392b898783fab938bcbf154553fc751a 398 Gene3D G3DSA:3.30.565.10 235 383 1.2E-35 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS10315 392b898783fab938bcbf154553fc751a 398 SMART SM00448 8 118 7.9E-35 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 L21SP4_RS10315 392b898783fab938bcbf154553fc751a 398 SMART SM00387 274 386 3.4E-26 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS00775 2414ade98341310158693d3f7793c3c2 210 SUPERFAMILY SSF54523 12 105 1.88E-15 T 22-04-2016 L21SP4_RS00775 2414ade98341310158693d3f7793c3c2 210 Gene3D G3DSA:3.30.700.10 12 54 1.3E-10 T 22-04-2016 L21SP4_RS00775 2414ade98341310158693d3f7793c3c2 210 Pfam PF13633 Prokaryotic N-terminal methylation site 10 35 9.9E-8 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site L21SP4_RS00775 2414ade98341310158693d3f7793c3c2 210 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 10 32 2.8E-7 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site L21SP4_RS00775 2414ade98341310158693d3f7793c3c2 210 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 10 30 - T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site L21SP4_RS02730 db807d6e1572c476709bd2f2b225a0b6 285 SUPERFAMILY SSF53335 50 278 9.1E-27 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS02730 db807d6e1572c476709bd2f2b225a0b6 285 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 70 283 2.1E-48 T 22-04-2016 L21SP4_RS02730 db807d6e1572c476709bd2f2b225a0b6 285 PANTHER PTHR18895 59 285 8.8E-45 T 22-04-2016 L21SP4_RS02730 db807d6e1572c476709bd2f2b225a0b6 285 PANTHER PTHR18895:SF3 59 285 8.8E-45 T 22-04-2016 L21SP4_RS02730 db807d6e1572c476709bd2f2b225a0b6 285 Gene3D G3DSA:3.40.50.150 113 273 1.0E-23 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS11825 9a136c0a07db848edb7df92047a1c85b 261 PANTHER PTHR35004 89 259 4.0E-14 T 22-04-2016 L21SP4_RS11825 9a136c0a07db848edb7df92047a1c85b 261 Pfam PF00665 Integrase core domain 126 258 1.5E-13 T 22-04-2016 IPR001584 Integrase, catalytic core GO:0015074 L21SP4_RS11825 9a136c0a07db848edb7df92047a1c85b 261 PANTHER PTHR35004:SF2 89 259 4.0E-14 T 22-04-2016 L21SP4_RS11825 9a136c0a07db848edb7df92047a1c85b 261 SUPERFAMILY SSF53098 126 259 7.59E-7 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS11825 9a136c0a07db848edb7df92047a1c85b 261 Gene3D G3DSA:3.30.420.10 126 260 6.5E-8 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS11825 9a136c0a07db848edb7df92047a1c85b 261 ProDom PD043187 TRANSPOSASE PLASMID CATALYTIC INTEGRASE DNA-BINDING DNA TRANSPOSITION RECOMBINATION FOR INSERTION 24 130 2.0E-15 T 22-04-2016 L21SP4_RS10125 641913ae0a5ce083c0f80201cfc40fdf 706 Gene3D G3DSA:3.30.1120.10 457 525 2.2E-15 T 22-04-2016 L21SP4_RS10125 641913ae0a5ce083c0f80201cfc40fdf 706 Gene3D G3DSA:3.40.720.10 30 455 1.8E-109 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS10125 641913ae0a5ce083c0f80201cfc40fdf 706 PANTHER PTHR10342:SF199 288 342 1.8E-139 T 22-04-2016 L21SP4_RS10125 641913ae0a5ce083c0f80201cfc40fdf 706 PANTHER PTHR10342:SF199 5 238 1.8E-139 T 22-04-2016 L21SP4_RS10125 641913ae0a5ce083c0f80201cfc40fdf 706 PANTHER PTHR10342:SF199 374 553 1.8E-139 T 22-04-2016 L21SP4_RS10125 641913ae0a5ce083c0f80201cfc40fdf 706 PANTHER PTHR10342 288 342 1.8E-139 T 22-04-2016 L21SP4_RS10125 641913ae0a5ce083c0f80201cfc40fdf 706 PANTHER PTHR10342 5 238 1.8E-139 T 22-04-2016 L21SP4_RS10125 641913ae0a5ce083c0f80201cfc40fdf 706 PANTHER PTHR10342 374 553 1.8E-139 T 22-04-2016 L21SP4_RS10125 641913ae0a5ce083c0f80201cfc40fdf 706 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 565 702 9.3E-7 T 22-04-2016 L21SP4_RS10125 641913ae0a5ce083c0f80201cfc40fdf 706 ProSitePatterns PS00149 Sulfatases signature 2. 123 133 - T 22-04-2016 IPR024607 Sulfatase, conserved site L21SP4_RS10125 641913ae0a5ce083c0f80201cfc40fdf 706 SUPERFAMILY SSF53649 31 523 1.96E-124 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS10125 641913ae0a5ce083c0f80201cfc40fdf 706 Pfam PF00884 Sulfatase 33 429 4.5E-72 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS10125 641913ae0a5ce083c0f80201cfc40fdf 706 SUPERFAMILY SSF49899 558 702 2.75E-11 T 22-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP4_RS10125 641913ae0a5ce083c0f80201cfc40fdf 706 Gene3D G3DSA:2.60.120.200 561 696 7.6E-4 T 22-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP4_RS04995 8135b3386e54baa73094ccce461badd4 287 Pfam PF02153 Prephenate dehydrogenase 11 263 2.0E-59 T 22-04-2016 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 L21SP4_RS04995 8135b3386e54baa73094ccce461badd4 287 PANTHER PTHR21363:SF0 2 269 2.8E-62 T 22-04-2016 L21SP4_RS04995 8135b3386e54baa73094ccce461badd4 287 PANTHER PTHR21363 2 269 2.8E-62 T 22-04-2016 L21SP4_RS04995 8135b3386e54baa73094ccce461badd4 287 SUPERFAMILY SSF51735 1 164 1.79E-38 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS04995 8135b3386e54baa73094ccce461badd4 287 SUPERFAMILY SSF48179 167 271 4.65E-29 T 22-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 L21SP4_RS04995 8135b3386e54baa73094ccce461badd4 287 Gene3D G3DSA:3.40.50.720 2 173 1.7E-31 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS11905 1aa98111de6e37657821beb3254bdf59 339 Pfam PF00809 Pterin binding enzyme 89 294 6.0E-26 T 22-04-2016 IPR000489 Pterin-binding domain GO:0042558 L21SP4_RS11905 1aa98111de6e37657821beb3254bdf59 339 Gene3D G3DSA:3.20.20.20 86 335 7.1E-53 T 22-04-2016 IPR000489 Pterin-binding domain GO:0042558 L21SP4_RS11905 1aa98111de6e37657821beb3254bdf59 339 SUPERFAMILY SSF51717 84 298 8.37E-48 T 22-04-2016 IPR011005 Dihydropteroate synthase-like GO:0044237 L21SP4_RS08410 180776f8959d15e968876b9bab412d14 102 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 6.0E-20 T 22-04-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 L21SP4_RS08410 180776f8959d15e968876b9bab412d14 102 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 6.0E-20 T 22-04-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 L21SP4_RS08410 180776f8959d15e968876b9bab412d14 102 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 6.0E-20 T 22-04-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 L21SP4_RS08410 180776f8959d15e968876b9bab412d14 102 Pfam PF00338 Ribosomal protein S10p/S20e 7 101 1.1E-37 T 22-04-2016 IPR027486 Ribosomal protein S10 domain L21SP4_RS08410 180776f8959d15e968876b9bab412d14 102 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 26.69 T 22-04-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 L21SP4_RS08410 180776f8959d15e968876b9bab412d14 102 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 22-04-2016 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS08410 180776f8959d15e968876b9bab412d14 102 SUPERFAMILY SSF54999 5 102 5.89E-39 T 22-04-2016 IPR027486 Ribosomal protein S10 domain L21SP4_RS08410 180776f8959d15e968876b9bab412d14 102 Gene3D G3DSA:3.30.70.600 4 102 4.8E-44 T 22-04-2016 IPR027486 Ribosomal protein S10 domain L21SP4_RS08410 180776f8959d15e968876b9bab412d14 102 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 1.2E-44 T 22-04-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 L21SP4_RS08410 180776f8959d15e968876b9bab412d14 102 SMART SM01403 7 101 5.8E-57 T 22-04-2016 IPR027486 Ribosomal protein S10 domain L21SP4_RS08410 180776f8959d15e968876b9bab412d14 102 PANTHER PTHR11700 4 102 1.0E-50 T 22-04-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 L21SP4_RS11270 f450c7321dc8a7cd291cf3167ab0fd88 385 Pfam PF13439 Glycosyltransferase Family 4 34 190 5.0E-8 T 22-04-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain L21SP4_RS11270 f450c7321dc8a7cd291cf3167ab0fd88 385 Gene3D G3DSA:3.40.50.2000 204 353 4.1E-29 T 22-04-2016 L21SP4_RS11270 f450c7321dc8a7cd291cf3167ab0fd88 385 PANTHER PTHR12526 38 51 2.0E-47 T 22-04-2016 L21SP4_RS11270 f450c7321dc8a7cd291cf3167ab0fd88 385 PANTHER PTHR12526 67 377 2.0E-47 T 22-04-2016 L21SP4_RS11270 f450c7321dc8a7cd291cf3167ab0fd88 385 Pfam PF00534 Glycosyl transferases group 1 195 354 7.4E-34 T 22-04-2016 IPR001296 Glycosyl transferase, family 1 L21SP4_RS11270 f450c7321dc8a7cd291cf3167ab0fd88 385 SUPERFAMILY SSF53756 30 377 1.15E-63 T 22-04-2016 L21SP4_RS03300 14286a0394a1993e60157d5b9a0a529b 196 PANTHER PTHR41878 1 193 8.6E-47 T 22-04-2016 L21SP4_RS03300 14286a0394a1993e60157d5b9a0a529b 196 Gene3D G3DSA:3.10.290.30 2 176 3.2E-59 T 22-04-2016 IPR024047 Protein MM3350-like domain L21SP4_RS03300 14286a0394a1993e60157d5b9a0a529b 196 SUPERFAMILY SSF159941 3 175 8.63E-61 T 22-04-2016 IPR024047 Protein MM3350-like domain L21SP4_RS03300 14286a0394a1993e60157d5b9a0a529b 196 PANTHER PTHR41878:SF1 1 193 8.6E-47 T 22-04-2016 L21SP4_RS03300 14286a0394a1993e60157d5b9a0a529b 196 Pfam PF07929 Plasmid pRiA4b ORF-3-like protein 5 172 4.6E-62 T 22-04-2016 IPR012912 Plasmid pRiA4b, Orf3 L21SP4_RS01030 012f724fb183654ce53816d19154baec 392 SMART SM00220 55 356 7.6E-19 T 22-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 L21SP4_RS01030 012f724fb183654ce53816d19154baec 392 SUPERFAMILY SSF56112 185 337 1.89E-46 T 22-04-2016 IPR011009 Protein kinase-like domain L21SP4_RS01030 012f724fb183654ce53816d19154baec 392 SUPERFAMILY SSF56112 54 156 1.89E-46 T 22-04-2016 IPR011009 Protein kinase-like domain L21SP4_RS01030 012f724fb183654ce53816d19154baec 392 Gene3D G3DSA:1.10.510.10 184 349 1.5E-36 T 22-04-2016 L21SP4_RS01030 012f724fb183654ce53816d19154baec 392 PANTHER PTHR24362 55 159 2.9E-36 T 22-04-2016 L21SP4_RS01030 012f724fb183654ce53816d19154baec 392 PANTHER PTHR24362 189 341 2.9E-36 T 22-04-2016 L21SP4_RS01030 012f724fb183654ce53816d19154baec 392 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 209 221 - T 22-04-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 L21SP4_RS01030 012f724fb183654ce53816d19154baec 392 Gene3D G3DSA:3.30.200.20 51 147 3.3E-12 T 22-04-2016 L21SP4_RS01030 012f724fb183654ce53816d19154baec 392 Pfam PF00069 Protein kinase domain 55 337 5.6E-33 T 22-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 L21SP4_RS11625 2e4ec0e8b171dc6f3c82dd5376ac98b7 662 Gene3D G3DSA:1.50.10.20 290 336 4.2E-4 T 22-04-2016 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid L21SP4_RS11625 2e4ec0e8b171dc6f3c82dd5376ac98b7 662 Gene3D G3DSA:1.50.10.20 87 179 4.2E-4 T 22-04-2016 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid L21SP4_RS11625 2e4ec0e8b171dc6f3c82dd5376ac98b7 662 Pfam PF07944 Beta-L-arabinofuranosidase, GH127 81 533 4.2E-34 T 22-04-2016 IPR012878 Beta-L-arabinofuranosidase, GH127 KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18 L21SP4_RS11625 2e4ec0e8b171dc6f3c82dd5376ac98b7 662 SUPERFAMILY SSF48208 82 375 1.36E-10 T 22-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP4_RS11625 2e4ec0e8b171dc6f3c82dd5376ac98b7 662 PANTHER PTHR31151:SF4 337 537 6.7E-17 T 22-04-2016 L21SP4_RS11625 2e4ec0e8b171dc6f3c82dd5376ac98b7 662 PANTHER PTHR31151 337 537 6.7E-17 T 22-04-2016 L21SP4_RS08830 11a423169e35647c87f291038cdf357e 255 Pfam PF00535 Glycosyl transferase family 2 4 144 1.5E-26 T 22-04-2016 IPR001173 Glycosyltransferase 2-like L21SP4_RS08830 11a423169e35647c87f291038cdf357e 255 SUPERFAMILY SSF53448 1 203 2.0E-42 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases L21SP4_RS08830 11a423169e35647c87f291038cdf357e 255 PANTHER PTHR10859 1 246 7.6E-65 T 22-04-2016 L21SP4_RS08830 11a423169e35647c87f291038cdf357e 255 Gene3D G3DSA:3.90.550.10 1 201 1.7E-28 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases L21SP4_RS10740 6ef4ff32cea6eb9e8ec92137ade39a6e 666 Gene3D G3DSA:2.130.10.10 584 649 8.1E-5 T 22-04-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 L21SP4_RS10740 6ef4ff32cea6eb9e8ec92137ade39a6e 666 ProSitePatterns PS00659 Glycosyl hydrolases family 5 signature. 119 128 - T 22-04-2016 IPR018087 Glycoside hydrolase, family 5, conserved site GO:0004553|GO:0005975 L21SP4_RS10740 6ef4ff32cea6eb9e8ec92137ade39a6e 666 SUPERFAMILY SSF51445 58 231 1.21E-19 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily L21SP4_RS10740 6ef4ff32cea6eb9e8ec92137ade39a6e 666 Gene3D G3DSA:3.20.20.80 62 217 9.0E-22 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP4_RS10740 6ef4ff32cea6eb9e8ec92137ade39a6e 666 Pfam PF01229 Glycosyl hydrolases family 39 120 195 1.5E-7 T 22-04-2016 IPR000514 Glycoside hydrolase, family 39 GO:0004553|GO:0005975 L21SP4_RS01475 6d944a85ea2692051c0b535a553e2aae 123 Pfam PF01022 Bacterial regulatory protein, arsR family 30 77 1.4E-11 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 L21SP4_RS01475 6d944a85ea2692051c0b535a553e2aae 123 PANTHER PTHR33154 18 112 1.3E-21 T 22-04-2016 L21SP4_RS01475 6d944a85ea2692051c0b535a553e2aae 123 Gene3D G3DSA:1.10.10.10 13 100 2.2E-23 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS01475 6d944a85ea2692051c0b535a553e2aae 123 SUPERFAMILY SSF46785 13 100 8.37E-22 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS01475 6d944a85ea2692051c0b535a553e2aae 123 SMART SM00418 23 99 8.7E-21 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 L21SP4_RS01475 6d944a85ea2692051c0b535a553e2aae 123 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 58 73 4.0E-11 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 L21SP4_RS01475 6d944a85ea2692051c0b535a553e2aae 123 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 73 88 4.0E-11 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 L21SP4_RS01475 6d944a85ea2692051c0b535a553e2aae 123 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 25 40 4.0E-11 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 L21SP4_RS07835 3b0311cc65a97cb80f140995a6051f60 278 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 23 43 - T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site L21SP4_RS07835 3b0311cc65a97cb80f140995a6051f60 278 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 22 45 7.0E-5 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site L21SP4_RS07835 3b0311cc65a97cb80f140995a6051f60 278 SUPERFAMILY SSF54523 25 100 7.85E-10 T 22-04-2016 L21SP4_RS07835 3b0311cc65a97cb80f140995a6051f60 278 Pfam PF13544 Type IV pilin N-term methylation site GFxxxE 19 43 2.8E-6 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site L21SP4_RS03700 6fb9b8e0d49c2c32a731447b630a08bb 887 PANTHER PTHR11670 743 886 0.0 T 22-04-2016 IPR015937 Aconitase/isopropylmalate dehydratase GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 L21SP4_RS03700 6fb9b8e0d49c2c32a731447b630a08bb 887 PANTHER PTHR11670 1 641 0.0 T 22-04-2016 IPR015937 Aconitase/isopropylmalate dehydratase GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 L21SP4_RS03700 6fb9b8e0d49c2c32a731447b630a08bb 887 PANTHER PTHR11670 657 702 0.0 T 22-04-2016 IPR015937 Aconitase/isopropylmalate dehydratase GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 L21SP4_RS03700 6fb9b8e0d49c2c32a731447b630a08bb 887 SUPERFAMILY SSF53732 17 616 3.79E-193 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 L21SP4_RS03700 6fb9b8e0d49c2c32a731447b630a08bb 887 Gene3D G3DSA:3.40.1060.10 247 365 1.0E-34 T 22-04-2016 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 L21SP4_RS03700 6fb9b8e0d49c2c32a731447b630a08bb 887 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 19 883 0.0 T 22-04-2016 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3 L21SP4_RS03700 6fb9b8e0d49c2c32a731447b630a08bb 887 Gene3D G3DSA:3.30.499.10 25 246 6.1E-65 T 22-04-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 L21SP4_RS03700 6fb9b8e0d49c2c32a731447b630a08bb 887 PRINTS PR00415 Aconitase family signature 146 159 7.67E-38 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 L21SP4_RS03700 6fb9b8e0d49c2c32a731447b630a08bb 887 PRINTS PR00415 Aconitase family signature 290 303 7.67E-38 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 L21SP4_RS03700 6fb9b8e0d49c2c32a731447b630a08bb 887 PRINTS PR00415 Aconitase family signature 170 178 7.67E-38 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 L21SP4_RS03700 6fb9b8e0d49c2c32a731447b630a08bb 887 PRINTS PR00415 Aconitase family signature 483 496 7.67E-38 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 L21SP4_RS03700 6fb9b8e0d49c2c32a731447b630a08bb 887 PRINTS PR00415 Aconitase family signature 276 289 7.67E-38 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 L21SP4_RS03700 6fb9b8e0d49c2c32a731447b630a08bb 887 PRINTS PR00415 Aconitase family signature 200 213 7.67E-38 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 L21SP4_RS03700 6fb9b8e0d49c2c32a731447b630a08bb 887 PRINTS PR00415 Aconitase family signature 421 432 7.67E-38 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 L21SP4_RS03700 6fb9b8e0d49c2c32a731447b630a08bb 887 PRINTS PR00415 Aconitase family signature 214 229 7.67E-38 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 L21SP4_RS03700 6fb9b8e0d49c2c32a731447b630a08bb 887 PRINTS PR00415 Aconitase family signature 370 384 7.67E-38 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 L21SP4_RS03700 6fb9b8e0d49c2c32a731447b630a08bb 887 Pfam PF00330 Aconitase family (aconitate hydratase) 77 552 2.8E-163 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 L21SP4_RS03700 6fb9b8e0d49c2c32a731447b630a08bb 887 Gene3D G3DSA:3.30.499.10 367 565 1.8E-53 T 22-04-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 L21SP4_RS03700 6fb9b8e0d49c2c32a731447b630a08bb 887 Pfam PF00694 Aconitase C-terminal domain 681 811 4.7E-40 T 22-04-2016 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 L21SP4_RS03700 6fb9b8e0d49c2c32a731447b630a08bb 887 ProSitePatterns PS01244 Aconitase family signature 2. 483 496 - T 22-04-2016 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33|UniPathway: UPA00048 L21SP4_RS03700 6fb9b8e0d49c2c32a731447b630a08bb 887 PANTHER PTHR11670:SF1 743 886 0.0 T 22-04-2016 L21SP4_RS03700 6fb9b8e0d49c2c32a731447b630a08bb 887 PANTHER PTHR11670:SF1 1 641 0.0 T 22-04-2016 L21SP4_RS03700 6fb9b8e0d49c2c32a731447b630a08bb 887 PANTHER PTHR11670:SF1 657 702 0.0 T 22-04-2016 L21SP4_RS03700 6fb9b8e0d49c2c32a731447b630a08bb 887 Gene3D G3DSA:3.20.19.10 627 882 6.4E-69 T 22-04-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel L21SP4_RS03700 6fb9b8e0d49c2c32a731447b630a08bb 887 ProSitePatterns PS00450 Aconitase family signature 1. 417 433 - T 22-04-2016 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33|UniPathway: UPA00048 L21SP4_RS03700 6fb9b8e0d49c2c32a731447b630a08bb 887 SUPERFAMILY SSF52016 621 883 8.04E-77 T 22-04-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel L21SP4_RS04405 d470c537b77e4b43ab6039cb736d1378 404 Gene3D G3DSA:3.20.20.210 187 359 9.8E-4 T 22-04-2016 L21SP4_RS03075 6ba4b1c718f68bbd0baeca7d2309dfe9 756 PANTHER PTHR32309 1 487 2.8E-73 T 22-04-2016 L21SP4_RS03075 6ba4b1c718f68bbd0baeca7d2309dfe9 756 PANTHER PTHR32309 534 743 2.8E-73 T 22-04-2016 L21SP4_RS03075 6ba4b1c718f68bbd0baeca7d2309dfe9 756 Gene3D G3DSA:3.40.50.300 575 714 1.6E-19 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS03075 6ba4b1c718f68bbd0baeca7d2309dfe9 756 SUPERFAMILY SSF57997 184 322 2.62E-5 T 22-04-2016 L21SP4_RS03075 6ba4b1c718f68bbd0baeca7d2309dfe9 756 SUPERFAMILY SSF52540 575 728 1.51E-21 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS03075 6ba4b1c718f68bbd0baeca7d2309dfe9 756 Pfam PF02706 Chain length determinant protein 27 166 4.2E-8 T 22-04-2016 IPR003856 Lipopolysaccharide biosynthesis GO:0009103|GO:0016020 L21SP4_RS03075 6ba4b1c718f68bbd0baeca7d2309dfe9 756 PANTHER PTHR32309:SF13 1 487 2.8E-73 T 22-04-2016 L21SP4_RS03075 6ba4b1c718f68bbd0baeca7d2309dfe9 756 PANTHER PTHR32309:SF13 534 743 2.8E-73 T 22-04-2016 L21SP4_RS04550 23c0b7617c4412c8e0dd42fa418eb69a 566 Gene3D G3DSA:2.160.20.10 153 154 9.3E-13 T 22-04-2016 IPR012334 Pectin lyase fold L21SP4_RS04550 23c0b7617c4412c8e0dd42fa418eb69a 566 Gene3D G3DSA:2.160.20.10 241 365 9.3E-13 T 22-04-2016 IPR012334 Pectin lyase fold L21SP4_RS04550 23c0b7617c4412c8e0dd42fa418eb69a 566 Gene3D G3DSA:2.160.20.10 16 93 9.3E-13 T 22-04-2016 IPR012334 Pectin lyase fold L21SP4_RS04550 23c0b7617c4412c8e0dd42fa418eb69a 566 SUPERFAMILY SSF51126 4 149 2.16E-17 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor L21SP4_RS04550 23c0b7617c4412c8e0dd42fa418eb69a 566 SUPERFAMILY SSF51126 185 374 2.16E-17 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor L21SP4_RS07190 f414280de8b0003c6c1e60139fb8edb5 476 PANTHER PTHR11328:SF24 13 475 6.3E-70 T 22-04-2016 L21SP4_RS07190 f414280de8b0003c6c1e60139fb8edb5 476 PANTHER PTHR11328 13 475 6.3E-70 T 22-04-2016 L21SP4_RS07190 f414280de8b0003c6c1e60139fb8edb5 476 SUPERFAMILY SSF103473 16 449 2.88E-30 T 22-04-2016 IPR020846 Major facilitator superfamily domain L21SP4_RS07190 f414280de8b0003c6c1e60139fb8edb5 476 Pfam PF13347 MFS/sugar transport protein 22 455 6.4E-66 T 22-04-2016 L21SP4_RS07190 f414280de8b0003c6c1e60139fb8edb5 476 Gene3D G3DSA:1.20.1250.20 249 447 6.8E-8 T 22-04-2016 L21SP4_RS07190 f414280de8b0003c6c1e60139fb8edb5 476 Gene3D G3DSA:1.20.1250.20 20 215 2.3E-14 T 22-04-2016 L21SP4_RS07190 f414280de8b0003c6c1e60139fb8edb5 476 ProSitePatterns PS00872 Sodium:galactoside symporter family signature. 70 95 - T 22-04-2016 IPR018043 Sodium:galactoside symporter, conserved site GO:0005215|GO:0006814|GO:0016020 L21SP4_RS07595 8cf1b41e5b28f32449fa369f61f14be6 132 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 55 131 3.4E-19 T 22-04-2016 IPR006260 TonB, C-terminal GO:0006810 L21SP4_RS07595 8cf1b41e5b28f32449fa369f61f14be6 132 SUPERFAMILY SSF74653 47 129 5.49E-24 T 22-04-2016 L21SP4_RS07595 8cf1b41e5b28f32449fa369f61f14be6 132 PRINTS PR01374 Gram-negative bacterial tonB protein signature 70 88 3.9E-11 T 22-04-2016 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 L21SP4_RS07595 8cf1b41e5b28f32449fa369f61f14be6 132 PRINTS PR01374 Gram-negative bacterial tonB protein signature 89 106 3.9E-11 T 22-04-2016 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 L21SP4_RS07595 8cf1b41e5b28f32449fa369f61f14be6 132 PRINTS PR01374 Gram-negative bacterial tonB protein signature 49 70 3.9E-11 T 22-04-2016 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 L21SP4_RS07595 8cf1b41e5b28f32449fa369f61f14be6 132 PANTHER PTHR33446 24 132 1.6E-17 T 22-04-2016 L21SP4_RS07595 8cf1b41e5b28f32449fa369f61f14be6 132 Gene3D G3DSA:3.30.1150.10 54 132 1.8E-11 T 22-04-2016 L21SP4_RS07595 8cf1b41e5b28f32449fa369f61f14be6 132 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 55 131 2.1E-22 T 22-04-2016 IPR006260 TonB, C-terminal GO:0006810 L21SP4_RS09480 8102e7a76d7ef008c7fe77d23a754bad 1359 SUPERFAMILY SSF51445 871 1108 8.0E-9 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily L21SP4_RS09480 8102e7a76d7ef008c7fe77d23a754bad 1359 Pfam PF01229 Glycosyl hydrolases family 39 891 981 1.3E-4 T 22-04-2016 IPR000514 Glycoside hydrolase, family 39 GO:0004553|GO:0005975 L21SP4_RS09480 8102e7a76d7ef008c7fe77d23a754bad 1359 Gene3D G3DSA:4.10.1080.10 316 361 1.0E-4 T 22-04-2016 IPR028974 TSP type-3 repeat GO:0005509 L21SP4_RS09480 8102e7a76d7ef008c7fe77d23a754bad 1359 Gene3D G3DSA:3.20.20.80 890 1062 7.9E-9 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP4_RS02500 6b75a48ba5813c46a99de2628c1e2557 562 Pfam PF08502 LeuA allosteric (dimerisation) domain 427 559 2.9E-24 T 22-04-2016 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 L21SP4_RS02500 6b75a48ba5813c46a99de2628c1e2557 562 PANTHER PTHR10277 362 560 6.5E-221 T 22-04-2016 L21SP4_RS02500 6b75a48ba5813c46a99de2628c1e2557 562 PANTHER PTHR10277 9 346 6.5E-221 T 22-04-2016 L21SP4_RS02500 6b75a48ba5813c46a99de2628c1e2557 562 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 39 55 - T 22-04-2016 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 L21SP4_RS02500 6b75a48ba5813c46a99de2628c1e2557 562 SMART SM00917 427 560 6.0E-27 T 22-04-2016 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 L21SP4_RS02500 6b75a48ba5813c46a99de2628c1e2557 562 Pfam PF00682 HMGL-like 33 313 9.3E-74 T 22-04-2016 IPR000891 Pyruvate carboxyltransferase GO:0003824 L21SP4_RS02500 6b75a48ba5813c46a99de2628c1e2557 562 SUPERFAMILY SSF89000 393 442 7.45E-11 T 22-04-2016 L21SP4_RS02500 6b75a48ba5813c46a99de2628c1e2557 562 SUPERFAMILY SSF110921 456 559 1.18E-28 T 22-04-2016 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 L21SP4_RS02500 6b75a48ba5813c46a99de2628c1e2557 562 PANTHER PTHR10277:SF28 362 560 6.5E-221 T 22-04-2016 L21SP4_RS02500 6b75a48ba5813c46a99de2628c1e2557 562 PANTHER PTHR10277:SF28 9 346 6.5E-221 T 22-04-2016 L21SP4_RS02500 6b75a48ba5813c46a99de2628c1e2557 562 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 243 256 - T 22-04-2016 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 L21SP4_RS02500 6b75a48ba5813c46a99de2628c1e2557 562 Gene3D G3DSA:3.20.20.70 15 399 2.8E-135 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP4_RS02500 6b75a48ba5813c46a99de2628c1e2557 562 SUPERFAMILY SSF51569 21 330 5.31E-91 T 22-04-2016 L21SP4_RS02420 2ef367739d605e733aa0b950021cd7c2 849 TIGRFAM TIGR02094 more_P_ylases: alpha-glucan phosphorylases 103 705 7.6E-249 T 22-04-2016 IPR011834 Alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 L21SP4_RS02420 2ef367739d605e733aa0b950021cd7c2 849 PANTHER PTHR11468 103 471 2.1E-240 T 22-04-2016 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: REACT_474 L21SP4_RS02420 2ef367739d605e733aa0b950021cd7c2 849 PANTHER PTHR11468 489 772 2.1E-240 T 22-04-2016 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: REACT_474 L21SP4_RS02420 2ef367739d605e733aa0b950021cd7c2 849 PANTHER PTHR11468:SF9 103 471 2.1E-240 T 22-04-2016 L21SP4_RS02420 2ef367739d605e733aa0b950021cd7c2 849 PANTHER PTHR11468:SF9 489 772 2.1E-240 T 22-04-2016 L21SP4_RS02420 2ef367739d605e733aa0b950021cd7c2 849 Pfam PF11897 Protein of unknown function (DUF3417) 13 116 1.1E-31 T 22-04-2016 IPR024517 Glycogen phosphorylase, domain of unknown function DUF3417 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 L21SP4_RS02420 2ef367739d605e733aa0b950021cd7c2 849 Gene3D G3DSA:3.40.50.2000 25 414 1.3E-74 T 22-04-2016 L21SP4_RS02420 2ef367739d605e733aa0b950021cd7c2 849 Pfam PF00343 Carbohydrate phosphorylase 266 616 2.1E-24 T 22-04-2016 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: REACT_474 L21SP4_RS02420 2ef367739d605e733aa0b950021cd7c2 849 Gene3D G3DSA:3.40.50.2000 415 705 1.7E-84 T 22-04-2016 L21SP4_RS02420 2ef367739d605e733aa0b950021cd7c2 849 SUPERFAMILY SSF53756 23 707 7.07E-203 T 22-04-2016 L21SP4_RS02420 2ef367739d605e733aa0b950021cd7c2 849 PIRSF PIRSF000460 1 791 1.5E-260 T 22-04-2016 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: REACT_474 L21SP4_RS05330 b9d1b4fbea33e3f77859743b6a0d9839 88 Gene3D G3DSA:3.30.70.1150 2 86 1.6E-13 T 22-04-2016 L21SP4_RS05330 b9d1b4fbea33e3f77859743b6a0d9839 88 SUPERFAMILY SSF55021 3 85 6.87E-13 T 22-04-2016 L21SP4_RS04660 f5e8cadb1316b4b0bc1e981e4d85ebf9 782 SUPERFAMILY SSF109604 546 721 1.19E-15 T 22-04-2016 L21SP4_RS04660 f5e8cadb1316b4b0bc1e981e4d85ebf9 782 Pfam PF01966 HD domain 547 692 6.4E-19 T 22-04-2016 IPR006674 HD domain L21SP4_RS04660 f5e8cadb1316b4b0bc1e981e4d85ebf9 782 SMART SM00471 543 702 1.0E-9 T 22-04-2016 IPR003607 HD/PDEase domain L21SP4_RS04660 f5e8cadb1316b4b0bc1e981e4d85ebf9 782 Pfam PF07698 7TM receptor with intracellular HD hydrolase 333 522 2.6E-25 T 22-04-2016 IPR011621 Metal-dependent phosphohydrolase, 7TM intracellular domain L21SP4_RS04660 f5e8cadb1316b4b0bc1e981e4d85ebf9 782 PANTHER PTHR36442 1 768 3.6E-161 T 22-04-2016 L21SP4_RS04660 f5e8cadb1316b4b0bc1e981e4d85ebf9 782 Pfam PF07697 7TM-HD extracellular 66 312 5.1E-32 T 22-04-2016 IPR011624 Metal-dependent phosphohydrolase, 7TM extracellular domain L21SP4_RS04660 f5e8cadb1316b4b0bc1e981e4d85ebf9 782 Gene3D G3DSA:1.10.3210.10 544 713 1.3E-23 T 22-04-2016 IPR006674 HD domain L21SP4_RS04660 f5e8cadb1316b4b0bc1e981e4d85ebf9 782 TIGRFAM TIGR00277 HDIG: HDIG domain 544 642 6.6E-24 T 22-04-2016 IPR006675 HDIG domain L21SP4_RS05265 30b02bd2e2357f1d6fb7745450477243 597 Pfam PF05430 S-adenosyl-L-methionine-dependent methyltransferase 462 540 6.2E-17 T 22-04-2016 IPR008471 MnmC-like methyltransferase GO:0016645|GO:0055114 L21SP4_RS05265 30b02bd2e2357f1d6fb7745450477243 597 SMART SM00729 28 261 5.9E-31 T 22-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 L21SP4_RS05265 30b02bd2e2357f1d6fb7745450477243 597 Gene3D G3DSA:3.40.50.150 336 552 2.4E-39 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS05265 30b02bd2e2357f1d6fb7745450477243 597 SUPERFAMILY SSF102114 18 268 4.19E-39 T 22-04-2016 L21SP4_RS05265 30b02bd2e2357f1d6fb7745450477243 597 PANTHER PTHR11135:SF1 12 456 9.4E-82 T 22-04-2016 IPR005911 Protein YhcC-like GO:0051536 L21SP4_RS05265 30b02bd2e2357f1d6fb7745450477243 597 Pfam PF04055 Radical SAM superfamily 34 216 6.8E-14 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 L21SP4_RS05265 30b02bd2e2357f1d6fb7745450477243 597 Pfam PF16199 Radical_SAM C-terminal domain 222 293 4.6E-19 T 22-04-2016 IPR032432 Radical SAM, C-terminal extension L21SP4_RS05265 30b02bd2e2357f1d6fb7745450477243 597 Gene3D G3DSA:3.80.30.20 29 245 6.8E-24 T 22-04-2016 IPR023404 Radical SAM, alpha/beta horseshoe L21SP4_RS05265 30b02bd2e2357f1d6fb7745450477243 597 SUPERFAMILY SSF53335 457 541 1.89E-16 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS05265 30b02bd2e2357f1d6fb7745450477243 597 SUPERFAMILY SSF53335 348 430 1.89E-16 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS05265 30b02bd2e2357f1d6fb7745450477243 597 TIGRFAM TIGR01212 TIGR01212: radical SAM protein, TIGR01212 family 12 314 1.1E-68 T 22-04-2016 IPR005911 Protein YhcC-like GO:0051536 L21SP4_RS05265 30b02bd2e2357f1d6fb7745450477243 597 PANTHER PTHR11135 12 456 9.4E-82 T 22-04-2016 L21SP4_RS07785 1baed8d1fc4ba9b21c116eb54c4f22ea 411 PANTHER PTHR30012:SF0 2 411 2.0E-85 T 22-04-2016 L21SP4_RS07785 1baed8d1fc4ba9b21c116eb54c4f22ea 411 Pfam PF00482 Type II secretion system (T2SS), protein F 75 191 6.8E-24 T 22-04-2016 IPR018076 Type II secretion system F domain L21SP4_RS07785 1baed8d1fc4ba9b21c116eb54c4f22ea 411 Pfam PF00482 Type II secretion system (T2SS), protein F 278 401 1.7E-22 T 22-04-2016 IPR018076 Type II secretion system F domain L21SP4_RS07785 1baed8d1fc4ba9b21c116eb54c4f22ea 411 PRINTS PR00812 Bacterial general secretion pathway protein F signature 168 196 7.5E-8 T 22-04-2016 IPR003004 GspF/PilC family L21SP4_RS07785 1baed8d1fc4ba9b21c116eb54c4f22ea 411 PRINTS PR00812 Bacterial general secretion pathway protein F signature 375 389 7.5E-8 T 22-04-2016 IPR003004 GspF/PilC family L21SP4_RS07785 1baed8d1fc4ba9b21c116eb54c4f22ea 411 PRINTS PR00812 Bacterial general secretion pathway protein F signature 70 82 7.5E-8 T 22-04-2016 IPR003004 GspF/PilC family L21SP4_RS07785 1baed8d1fc4ba9b21c116eb54c4f22ea 411 PANTHER PTHR30012 2 411 2.0E-85 T 22-04-2016 L21SP4_RS07705 677e2856cc1977ba611a0461a021555c 56 Gene3D G3DSA:3.30.70.20 5 54 2.7E-17 T 22-04-2016 L21SP4_RS07705 677e2856cc1977ba611a0461a021555c 56 SUPERFAMILY SSF54862 1 54 4.19E-18 T 22-04-2016 L21SP4_RS07705 677e2856cc1977ba611a0461a021555c 56 Pfam PF12838 4Fe-4S dicluster domain 9 52 8.3E-10 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain L21SP4_RS07705 677e2856cc1977ba611a0461a021555c 56 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 38 49 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site L21SP4_RS07705 677e2856cc1977ba611a0461a021555c 56 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 9 20 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site L21SP4_RS07705 677e2856cc1977ba611a0461a021555c 56 PRINTS PR00354 7Fe ferredoxin signature 17 27 5.65E-8 T 22-04-2016 IPR000813 7Fe ferredoxin GO:0009055 L21SP4_RS07705 677e2856cc1977ba611a0461a021555c 56 PRINTS PR00354 7Fe ferredoxin signature 33 50 5.65E-8 T 22-04-2016 IPR000813 7Fe ferredoxin GO:0009055 L21SP4_RS06225 3024b8fe11c9f10865615265ae6bfa63 258 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 1 252 14.673 T 22-04-2016 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 UniPathway: UPA00664 L21SP4_RS06225 3024b8fe11c9f10865615265ae6bfa63 258 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 3 246 5.3E-61 T 22-04-2016 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 UniPathway: UPA00664 L21SP4_RS06225 3024b8fe11c9f10865615265ae6bfa63 258 PANTHER PTHR30589 1 251 1.7E-72 T 22-04-2016 L21SP4_RS06225 3024b8fe11c9f10865615265ae6bfa63 258 PANTHER PTHR30589:SF0 1 251 1.7E-72 T 22-04-2016 L21SP4_RS06225 3024b8fe11c9f10865615265ae6bfa63 258 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 3 252 1.4E-44 T 22-04-2016 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 UniPathway: UPA00664 L21SP4_RS02280 71ab52b4c53d7d4c1b7f85264f8e3178 334 Pfam PF01820 D-ala D-ala ligase N-terminus 8 88 2.4E-19 T 22-04-2016 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 L21SP4_RS02280 71ab52b4c53d7d4c1b7f85264f8e3178 334 Pfam PF07478 D-ala D-ala ligase C-terminus 142 316 3.4E-45 T 22-04-2016 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 L21SP4_RS02280 71ab52b4c53d7d4c1b7f85264f8e3178 334 Gene3D G3DSA:3.40.50.20 7 86 2.9E-23 T 22-04-2016 IPR016185 Pre-ATP-grasp domain L21SP4_RS02280 71ab52b4c53d7d4c1b7f85264f8e3178 334 SUPERFAMILY SSF56059 98 324 1.51E-46 T 22-04-2016 L21SP4_RS02280 71ab52b4c53d7d4c1b7f85264f8e3178 334 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 262 290 - T 22-04-2016 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 L21SP4_RS02280 71ab52b4c53d7d4c1b7f85264f8e3178 334 Gene3D G3DSA:3.30.1490.20 110 194 3.3E-13 T 22-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 L21SP4_RS02280 71ab52b4c53d7d4c1b7f85264f8e3178 334 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 7 320 32.371 T 22-04-2016 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 L21SP4_RS02280 71ab52b4c53d7d4c1b7f85264f8e3178 334 PANTHER PTHR23132 4 321 8.5E-69 T 22-04-2016 L21SP4_RS02280 71ab52b4c53d7d4c1b7f85264f8e3178 334 Gene3D G3DSA:3.30.470.20 87 105 5.3E-43 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 L21SP4_RS02280 71ab52b4c53d7d4c1b7f85264f8e3178 334 Gene3D G3DSA:3.30.470.20 195 319 5.3E-43 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 L21SP4_RS02280 71ab52b4c53d7d4c1b7f85264f8e3178 334 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 8 319 2.6E-77 T 22-04-2016 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 L21SP4_RS02280 71ab52b4c53d7d4c1b7f85264f8e3178 334 SUPERFAMILY SSF52440 7 98 1.25E-23 T 22-04-2016 IPR016185 Pre-ATP-grasp domain L21SP4_RS09065 c929c41b6be4afae2a59bd685fe23ad7 172 SMART SM01001 7 158 6.4E-88 T 22-04-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 L21SP4_RS09065 c929c41b6be4afae2a59bd685fe23ad7 172 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 9 163 1.1E-58 T 22-04-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 L21SP4_RS09065 c929c41b6be4afae2a59bd685fe23ad7 172 Gene3D G3DSA:3.40.50.7700 3 166 1.9E-68 T 22-04-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 L21SP4_RS09065 c929c41b6be4afae2a59bd685fe23ad7 172 SUPERFAMILY SSF52255 8 165 1.31E-60 T 22-04-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 L21SP4_RS09065 c929c41b6be4afae2a59bd685fe23ad7 172 PIRSF PIRSF001338 4 169 1.7E-62 T 22-04-2016 IPR024694 N5-carboxyaminoimidazole ribonucleotide mutase PurE GO:0006189|GO:0034023 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234|UniPathway: UPA00074 L21SP4_RS09065 c929c41b6be4afae2a59bd685fe23ad7 172 PANTHER PTHR23046:SF2 8 171 1.4E-74 T 22-04-2016 L21SP4_RS09065 c929c41b6be4afae2a59bd685fe23ad7 172 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 9 162 30.272 T 22-04-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 L21SP4_RS09065 c929c41b6be4afae2a59bd685fe23ad7 172 Pfam PF00731 AIR carboxylase 8 156 1.7E-59 T 22-04-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 L21SP4_RS09065 c929c41b6be4afae2a59bd685fe23ad7 172 PANTHER PTHR23046 8 171 1.4E-74 T 22-04-2016 L21SP4_RS05020 d8aa8d73ec8c0f231e02ea627d30fa95 93 PANTHER PTHR33175 1 90 1.6E-30 T 22-04-2016 L21SP4_RS05020 d8aa8d73ec8c0f231e02ea627d30fa95 93 SUPERFAMILY SSF47729 1 91 4.27E-25 T 22-04-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 L21SP4_RS05020 d8aa8d73ec8c0f231e02ea627d30fa95 93 SMART SM00411 1 91 1.7E-28 T 22-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 L21SP4_RS05020 d8aa8d73ec8c0f231e02ea627d30fa95 93 PANTHER PTHR33175:SF5 1 90 1.6E-30 T 22-04-2016 L21SP4_RS05020 d8aa8d73ec8c0f231e02ea627d30fa95 93 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 6.2E-5 T 22-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 L21SP4_RS05020 d8aa8d73ec8c0f231e02ea627d30fa95 93 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 6.2E-5 T 22-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 L21SP4_RS05020 d8aa8d73ec8c0f231e02ea627d30fa95 93 Gene3D G3DSA:4.10.520.10 1 90 5.0E-29 T 22-04-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 L21SP4_RS05020 d8aa8d73ec8c0f231e02ea627d30fa95 93 Pfam PF00216 Bacterial DNA-binding protein 1 89 4.4E-29 T 22-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 L21SP4_RS01295 0151fbd8841182cddef95c4f384826c2 574 Gene3D G3DSA:3.40.50.300 305 574 1.9E-94 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS01295 0151fbd8841182cddef95c4f384826c2 574 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 48 149 1.5E-17 T 22-04-2016 IPR007831 General secretory system II, protein E, N-terminal GO:0005524|GO:0006810 L21SP4_RS01295 0151fbd8841182cddef95c4f384826c2 574 PANTHER PTHR30258:SF2 1 572 3.4E-201 T 22-04-2016 L21SP4_RS01295 0151fbd8841182cddef95c4f384826c2 574 SUPERFAMILY SSF52540 182 574 1.02E-100 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS01295 0151fbd8841182cddef95c4f384826c2 574 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 394 408 - T 22-04-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 L21SP4_RS01295 0151fbd8841182cddef95c4f384826c2 574 PANTHER PTHR30258 1 572 3.4E-201 T 22-04-2016 L21SP4_RS01295 0151fbd8841182cddef95c4f384826c2 574 Pfam PF00437 Type II/IV secretion system protein 202 466 1.7E-73 T 22-04-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 L21SP4_RS01295 0151fbd8841182cddef95c4f384826c2 574 SUPERFAMILY SSF160246 10 146 7.06E-26 T 22-04-2016 L21SP4_RS01295 0151fbd8841182cddef95c4f384826c2 574 SMART SM00382 327 448 1.1E-4 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS01295 0151fbd8841182cddef95c4f384826c2 574 Gene3D G3DSA:3.30.450.90 175 299 1.9E-48 T 22-04-2016 L21SP4_RS08515 e6ac556986c8781e39a3008d92df22b2 343 Pfam PF04055 Radical SAM superfamily 55 190 4.2E-11 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 L21SP4_RS08515 e6ac556986c8781e39a3008d92df22b2 343 PANTHER PTHR22976:SF17 2 339 1.1E-107 T 22-04-2016 L21SP4_RS08515 e6ac556986c8781e39a3008d92df22b2 343 PANTHER PTHR22976 2 339 1.1E-107 T 22-04-2016 L21SP4_RS08515 e6ac556986c8781e39a3008d92df22b2 343 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 230 331 2.5E-20 T 22-04-2016 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380|UniPathway: UPA00078 L21SP4_RS08515 e6ac556986c8781e39a3008d92df22b2 343 Gene3D G3DSA:3.20.20.70 13 334 1.2E-40 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP4_RS08515 e6ac556986c8781e39a3008d92df22b2 343 SUPERFAMILY SSF102114 12 334 4.97E-45 T 22-04-2016 L21SP4_RS08515 e6ac556986c8781e39a3008d92df22b2 343 SMART SM00876 229 333 1.4E-23 T 22-04-2016 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380|UniPathway: UPA00078 L21SP4_RS00915 7039957ce2d71223e488cfb64249fcc8 301 PANTHER PTHR10264 85 291 4.8E-73 T 22-04-2016 IPR001972 Stomatin family GO:0016020 L21SP4_RS00915 7039957ce2d71223e488cfb64249fcc8 301 PANTHER PTHR10264 17 62 4.8E-73 T 22-04-2016 IPR001972 Stomatin family GO:0016020 L21SP4_RS00915 7039957ce2d71223e488cfb64249fcc8 301 SMART SM00244 29 211 2.7E-23 T 22-04-2016 IPR001107 Band 7 domain L21SP4_RS00915 7039957ce2d71223e488cfb64249fcc8 301 Pfam PF01145 SPFH domain / Band 7 family 33 227 1.4E-22 T 22-04-2016 IPR001107 Band 7 domain L21SP4_RS00915 7039957ce2d71223e488cfb64249fcc8 301 PANTHER PTHR10264:SF51 85 291 4.8E-73 T 22-04-2016 IPR010201 HflK GO:0016021 L21SP4_RS00915 7039957ce2d71223e488cfb64249fcc8 301 PANTHER PTHR10264:SF51 17 62 4.8E-73 T 22-04-2016 IPR010201 HflK GO:0016021 L21SP4_RS00915 7039957ce2d71223e488cfb64249fcc8 301 SUPERFAMILY SSF117892 105 218 1.22E-17 T 22-04-2016 IPR001107 Band 7 domain L21SP4_RS00915 7039957ce2d71223e488cfb64249fcc8 301 TIGRFAM TIGR01933 hflK: HflK protein 31 292 2.3E-79 T 22-04-2016 IPR010201 HflK GO:0016021 L21SP4_RS04980 95b7976a26b00b991fad69cd9faa508f 357 SUPERFAMILY SSF48600 2 89 3.85E-23 T 22-04-2016 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 L21SP4_RS04980 95b7976a26b00b991fad69cd9faa508f 357 Gene3D G3DSA:3.40.190.10 85 175 4.6E-32 T 22-04-2016 L21SP4_RS04980 95b7976a26b00b991fad69cd9faa508f 357 Gene3D G3DSA:1.20.59.10 1 84 4.8E-24 T 22-04-2016 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 L21SP4_RS04980 95b7976a26b00b991fad69cd9faa508f 357 ProSitePatterns PS00858 Prephenate dehydratase signature 2. 299 306 - T 22-04-2016 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432|UniPathway: UPA00121 L21SP4_RS04980 95b7976a26b00b991fad69cd9faa508f 357 Pfam PF01842 ACT domain 272 336 1.3E-8 T 22-04-2016 IPR002912 ACT domain GO:0008152|GO:0016597 L21SP4_RS04980 95b7976a26b00b991fad69cd9faa508f 357 SMART SM00830 7 86 3.6E-30 T 22-04-2016 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 L21SP4_RS04980 95b7976a26b00b991fad69cd9faa508f 357 SUPERFAMILY SSF53850 87 269 1.52E-57 T 22-04-2016 L21SP4_RS04980 95b7976a26b00b991fad69cd9faa508f 357 Pfam PF01817 Chorismate mutase type II 7 83 3.7E-25 T 22-04-2016 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 L21SP4_RS04980 95b7976a26b00b991fad69cd9faa508f 357 TIGRFAM TIGR01807 CM_P2: chorismate mutase 3 76 2.9E-25 T 22-04-2016 IPR010957 Gamma/beta/epsilon proteobacterial P-protein, chorismate mutase domain GO:0004106|GO:0005737|GO:0009094 KEGG: 00400+5.4.99.5+4.2.1.51|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7432|MetaCyc: PWY-7626|UniPathway: UPA00120|UniPathway: UPA00121 L21SP4_RS04980 95b7976a26b00b991fad69cd9faa508f 357 ProSitePatterns PS00857 Prephenate dehydratase signature 1. 237 259 - T 22-04-2016 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432|UniPathway: UPA00121 L21SP4_RS04980 95b7976a26b00b991fad69cd9faa508f 357 Gene3D G3DSA:3.40.190.10 176 249 4.6E-23 T 22-04-2016 L21SP4_RS04980 95b7976a26b00b991fad69cd9faa508f 357 SUPERFAMILY SSF55021 256 350 2.92E-29 T 22-04-2016 L21SP4_RS04980 95b7976a26b00b991fad69cd9faa508f 357 PIRSF PIRSF001500 1 353 2.4E-127 T 22-04-2016 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432|UniPathway: UPA00121 L21SP4_RS04980 95b7976a26b00b991fad69cd9faa508f 357 PANTHER PTHR21022 3 350 6.1E-132 T 22-04-2016 L21SP4_RS04980 95b7976a26b00b991fad69cd9faa508f 357 Gene3D G3DSA:3.30.70.260 266 351 2.1E-34 T 22-04-2016 L21SP4_RS04980 95b7976a26b00b991fad69cd9faa508f 357 PANTHER PTHR21022:SF0 3 350 6.1E-132 T 22-04-2016 L21SP4_RS04980 95b7976a26b00b991fad69cd9faa508f 357 Pfam PF00800 Prephenate dehydratase 88 261 4.6E-61 T 22-04-2016 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432|UniPathway: UPA00121 L21SP4_RS11520 9cc0a41b5703eed200b4b1699d4aee50 454 Gene3D G3DSA:1.25.40.10 297 391 1.4E-4 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS11520 9cc0a41b5703eed200b4b1699d4aee50 454 Gene3D G3DSA:1.25.40.10 74 178 1.4E-4 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS00115 f9bcf5a50f1a93c7af13f3f81c912a2d 141 Gene3D G3DSA:2.60.40.790 5 138 1.2E-36 T 22-04-2016 IPR008978 HSP20-like chaperone L21SP4_RS00115 f9bcf5a50f1a93c7af13f3f81c912a2d 141 PANTHER PTHR11527 5 141 8.5E-36 T 22-04-2016 IPR031107 Small heat shock protein HSP20 L21SP4_RS00115 f9bcf5a50f1a93c7af13f3f81c912a2d 141 Pfam PF00011 Hsp20/alpha crystallin family 39 137 1.0E-23 T 22-04-2016 IPR002068 Alpha crystallin/Hsp20 domain L21SP4_RS00115 f9bcf5a50f1a93c7af13f3f81c912a2d 141 PANTHER PTHR11527:SF122 5 141 8.5E-36 T 22-04-2016 L21SP4_RS00115 f9bcf5a50f1a93c7af13f3f81c912a2d 141 SUPERFAMILY SSF49764 13 137 2.88E-36 T 22-04-2016 IPR008978 HSP20-like chaperone L21SP4_RS07320 04662947c9985a6199c3f5b7b7248368 494 SUPERFAMILY SSF53067 256 487 4.36E-39 T 22-04-2016 L21SP4_RS07320 04662947c9985a6199c3f5b7b7248368 494 PANTHER PTHR10196:SF6 5 494 1.5E-195 T 22-04-2016 L21SP4_RS07320 04662947c9985a6199c3f5b7b7248368 494 PIRSF PIRSF000538 4 493 2.4E-41 T 22-04-2016 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 L21SP4_RS07320 04662947c9985a6199c3f5b7b7248368 494 SUPERFAMILY SSF53067 7 250 1.77E-46 T 22-04-2016 L21SP4_RS07320 04662947c9985a6199c3f5b7b7248368 494 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 258 449 7.4E-35 T 22-04-2016 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 L21SP4_RS07320 04662947c9985a6199c3f5b7b7248368 494 Gene3D G3DSA:3.30.420.40 259 489 4.3E-18 T 22-04-2016 L21SP4_RS07320 04662947c9985a6199c3f5b7b7248368 494 Gene3D G3DSA:3.30.420.40 4 246 2.1E-26 T 22-04-2016 L21SP4_RS07320 04662947c9985a6199c3f5b7b7248368 494 PANTHER PTHR10196 5 494 1.5E-195 T 22-04-2016 L21SP4_RS07320 04662947c9985a6199c3f5b7b7248368 494 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 7 247 7.1E-29 T 22-04-2016 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 L21SP4_RS00085 1a66e4d85d784518b7611ae2fce34368 150 Gene3D G3DSA:3.40.50.620 5 147 8.0E-15 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP4_RS00085 1a66e4d85d784518b7611ae2fce34368 150 SUPERFAMILY SSF52402 5 147 2.51E-15 T 22-04-2016 L21SP4_RS00085 1a66e4d85d784518b7611ae2fce34368 150 Pfam PF00582 Universal stress protein family 5 147 5.0E-10 T 22-04-2016 IPR006016 UspA GO:0006950 L21SP4_RS01065 044fac7835a6276adf0257d307a7b521 439 PANTHER PTHR22604 4 422 1.2E-101 T 22-04-2016 L21SP4_RS01065 044fac7835a6276adf0257d307a7b521 439 SUPERFAMILY SSF55347 178 207 5.89E-18 T 22-04-2016 L21SP4_RS01065 044fac7835a6276adf0257d307a7b521 439 SUPERFAMILY SSF55347 240 388 5.89E-18 T 22-04-2016 L21SP4_RS01065 044fac7835a6276adf0257d307a7b521 439 Gene3D G3DSA:3.30.360.10 190 413 2.0E-21 T 22-04-2016 L21SP4_RS01065 044fac7835a6276adf0257d307a7b521 439 SUPERFAMILY SSF51735 24 201 3.95E-43 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS01065 044fac7835a6276adf0257d307a7b521 439 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 43 172 8.6E-16 T 22-04-2016 IPR000683 Oxidoreductase, N-terminal GO:0016491 L21SP4_RS01065 044fac7835a6276adf0257d307a7b521 439 Gene3D G3DSA:3.40.50.720 35 189 8.4E-43 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS01065 044fac7835a6276adf0257d307a7b521 439 PANTHER PTHR22604:SF122 4 422 1.2E-101 T 22-04-2016 L21SP4_RS09350 62fd9f92a8b92572dc93a5f1fc2ec785 662 PANTHER PTHR30572:SF7 1 662 3.0E-107 T 22-04-2016 L21SP4_RS09350 62fd9f92a8b92572dc93a5f1fc2ec785 662 PANTHER PTHR30572 1 662 3.0E-107 T 22-04-2016 L21SP4_RS09350 62fd9f92a8b92572dc93a5f1fc2ec785 662 Pfam PF12704 MacB-like periplasmic core domain 280 500 3.9E-37 T 22-04-2016 IPR025857 MacB-like periplasmic core domain L21SP4_RS09350 62fd9f92a8b92572dc93a5f1fc2ec785 662 Gene3D G3DSA:3.40.50.300 1 218 6.1E-64 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS09350 62fd9f92a8b92572dc93a5f1fc2ec785 662 Pfam PF00005 ABC transporter 22 166 1.0E-29 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 L21SP4_RS09350 62fd9f92a8b92572dc93a5f1fc2ec785 662 SMART SM00382 30 214 1.3E-14 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS09350 62fd9f92a8b92572dc93a5f1fc2ec785 662 Pfam PF02687 FtsX-like permease family 543 655 4.9E-23 T 22-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 L21SP4_RS09350 62fd9f92a8b92572dc93a5f1fc2ec785 662 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 L21SP4_RS09350 62fd9f92a8b92572dc93a5f1fc2ec785 662 SUPERFAMILY SSF52540 1 219 1.54E-67 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS02600 78c57b0271653f6d2d74e33b09bbb21e 802 Pfam PF03483 B3/4 domain 214 387 7.2E-66 T 22-04-2016 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 L21SP4_RS02600 78c57b0271653f6d2d74e33b09bbb21e 802 SMART SM00873 214 387 4.9E-90 T 22-04-2016 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 L21SP4_RS02600 78c57b0271653f6d2d74e33b09bbb21e 802 Gene3D G3DSA:3.30.56.10 155 184 5.9E-24 T 22-04-2016 L21SP4_RS02600 78c57b0271653f6d2d74e33b09bbb21e 802 Gene3D G3DSA:3.30.56.10 1 38 5.9E-24 T 22-04-2016 L21SP4_RS02600 78c57b0271653f6d2d74e33b09bbb21e 802 SUPERFAMILY SSF54991 704 800 3.27E-26 T 22-04-2016 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 L21SP4_RS02600 78c57b0271653f6d2d74e33b09bbb21e 802 Gene3D G3DSA:3.30.70.380 709 800 1.3E-28 T 22-04-2016 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 L21SP4_RS02600 78c57b0271653f6d2d74e33b09bbb21e 802 Pfam PF03147 Ferredoxin-fold anticodon binding domain 709 800 1.1E-26 T 22-04-2016 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 L21SP4_RS02600 78c57b0271653f6d2d74e33b09bbb21e 802 Gene3D G3DSA:3.30.56.20 403 479 7.4E-19 T 22-04-2016 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20 L21SP4_RS02600 78c57b0271653f6d2d74e33b09bbb21e 802 Gene3D G3DSA:2.40.50.140 42 152 2.6E-35 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold L21SP4_RS02600 78c57b0271653f6d2d74e33b09bbb21e 802 Gene3D G3DSA:3.30.930.10 498 695 9.0E-36 T 22-04-2016 L21SP4_RS02600 78c57b0271653f6d2d74e33b09bbb21e 802 SUPERFAMILY SSF46955 405 479 1.65E-13 T 22-04-2016 IPR009061 Putative DNA-binding domain L21SP4_RS02600 78c57b0271653f6d2d74e33b09bbb21e 802 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 794 38.949 T 22-04-2016 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 L21SP4_RS02600 78c57b0271653f6d2d74e33b09bbb21e 802 SMART SM00896 707 800 5.5E-35 T 22-04-2016 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 L21SP4_RS02600 78c57b0271653f6d2d74e33b09bbb21e 802 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 800 1.2E-225 T 22-04-2016 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 L21SP4_RS02600 78c57b0271653f6d2d74e33b09bbb21e 802 SUPERFAMILY SSF50249 39 192 1.29E-43 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold L21SP4_RS02600 78c57b0271653f6d2d74e33b09bbb21e 802 PANTHER PTHR10947:SF0 2 800 2.9E-257 T 22-04-2016 L21SP4_RS02600 78c57b0271653f6d2d74e33b09bbb21e 802 Pfam PF01588 Putative tRNA binding domain 45 145 1.3E-18 T 22-04-2016 IPR002547 tRNA-binding domain GO:0000049 Reactome: REACT_71 L21SP4_RS02600 78c57b0271653f6d2d74e33b09bbb21e 802 PANTHER PTHR10947 2 800 2.9E-257 T 22-04-2016 L21SP4_RS02600 78c57b0271653f6d2d74e33b09bbb21e 802 SUPERFAMILY SSF56037 202 397 3.14E-71 T 22-04-2016 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 L21SP4_RS02600 78c57b0271653f6d2d74e33b09bbb21e 802 SMART SM00874 404 475 4.4E-20 T 22-04-2016 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20 L21SP4_RS02600 78c57b0271653f6d2d74e33b09bbb21e 802 Gene3D G3DSA:3.50.40.10 201 397 5.7E-82 T 22-04-2016 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 L21SP4_RS02600 78c57b0271653f6d2d74e33b09bbb21e 802 SUPERFAMILY SSF55681 471 694 2.58E-29 T 22-04-2016 L21SP4_RS02600 78c57b0271653f6d2d74e33b09bbb21e 802 Pfam PF03484 tRNA synthetase B5 domain 407 474 2.9E-13 T 22-04-2016 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20 L21SP4_RS11580 cabaa741248c88b5e1e5ea9bbf4cda3a 327 Gene3D G3DSA:3.40.630.40 125 319 1.5E-52 T 22-04-2016 IPR002508 Cell wall hydrolase/autolysin, catalytic GO:0008745|GO:0009253 L21SP4_RS11580 cabaa741248c88b5e1e5ea9bbf4cda3a 327 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 126 316 1.2E-43 T 22-04-2016 IPR002508 Cell wall hydrolase/autolysin, catalytic GO:0008745|GO:0009253 L21SP4_RS11580 cabaa741248c88b5e1e5ea9bbf4cda3a 327 SUPERFAMILY SSF53187 124 318 4.08E-50 T 22-04-2016 L21SP4_RS11580 cabaa741248c88b5e1e5ea9bbf4cda3a 327 PANTHER PTHR30404:SF0 103 318 1.5E-52 T 22-04-2016 L21SP4_RS11580 cabaa741248c88b5e1e5ea9bbf4cda3a 327 PANTHER PTHR30404 103 318 1.5E-52 T 22-04-2016 L21SP4_RS11580 cabaa741248c88b5e1e5ea9bbf4cda3a 327 SMART SM00646 185 316 7.1E-33 T 22-04-2016 IPR002508 Cell wall hydrolase/autolysin, catalytic GO:0008745|GO:0009253 L21SP4_RS09560 c55db427ff7f94ff1406d771956db430 362 SUPERFAMILY SSF53639 1 61 4.71E-21 T 22-04-2016 IPR001303 Class II aldolase/adducin N-terminal L21SP4_RS09560 c55db427ff7f94ff1406d771956db430 362 SUPERFAMILY SSF53639 88 193 4.71E-21 T 22-04-2016 IPR001303 Class II aldolase/adducin N-terminal L21SP4_RS09560 c55db427ff7f94ff1406d771956db430 362 SMART SM01007 10 209 9.6E-12 T 22-04-2016 IPR001303 Class II aldolase/adducin N-terminal L21SP4_RS09560 c55db427ff7f94ff1406d771956db430 362 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 12 198 3.4E-21 T 22-04-2016 IPR001303 Class II aldolase/adducin N-terminal L21SP4_RS09560 c55db427ff7f94ff1406d771956db430 362 Gene3D G3DSA:3.40.225.10 5 211 1.4E-21 T 22-04-2016 IPR001303 Class II aldolase/adducin N-terminal L21SP4_RS08315 465f96a10af9194ae107f40afc571272 146 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 2 142 4.3E-51 T 22-04-2016 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 L21SP4_RS08315 465f96a10af9194ae107f40afc571272 146 ProSitePatterns PS00475 Ribosomal protein L15 signature. 109 139 - T 22-04-2016 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS08315 465f96a10af9194ae107f40afc571272 146 SUPERFAMILY SSF52080 4 145 8.11E-49 T 22-04-2016 IPR021131 Ribosomal protein L18e/L15P L21SP4_RS08315 465f96a10af9194ae107f40afc571272 146 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 28 144 3.6E-38 T 22-04-2016 IPR021131 Ribosomal protein L18e/L15P L21SP4_RS08315 465f96a10af9194ae107f40afc571272 146 PANTHER PTHR12934 1 145 1.8E-68 T 22-04-2016 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 L21SP4_RS08315 465f96a10af9194ae107f40afc571272 146 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 3 145 21.966 T 22-04-2016 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 L21SP4_RS08315 465f96a10af9194ae107f40afc571272 146 Gene3D G3DSA:3.100.10.10 32 145 1.5E-37 T 22-04-2016 L21SP4_RS11760 e7f7b020e550347d94f1fc237ada0483 1303 Pfam PF17132 alpha-L-rhamnosidase 210 1065 1.9E-174 T 22-04-2016 IPR033400 Alpha-L-rhamnosidase RhaM L21SP4_RS11760 e7f7b020e550347d94f1fc237ada0483 1303 PANTHER PTHR22925 515 708 1.7E-38 T 22-04-2016 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 L21SP4_RS11760 e7f7b020e550347d94f1fc237ada0483 1303 Gene3D G3DSA:2.60.120.260 1105 1240 2.1E-9 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS11760 e7f7b020e550347d94f1fc237ada0483 1303 SUPERFAMILY SSF49785 1094 1227 7.9E-16 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS11760 e7f7b020e550347d94f1fc237ada0483 1303 PANTHER PTHR22925:SF40 515 708 1.7E-38 T 22-04-2016 L21SP4_RS10730 dccc37591efc778627497fbf06a7379a 397 Gene3D G3DSA:3.40.50.300 11 141 3.0E-9 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS10730 dccc37591efc778627497fbf06a7379a 397 PANTHER PTHR33295 1 377 5.8E-42 T 22-04-2016 L21SP4_RS10730 dccc37591efc778627497fbf06a7379a 397 Pfam PF13173 AAA domain 22 151 1.1E-20 T 22-04-2016 L21SP4_RS10730 dccc37591efc778627497fbf06a7379a 397 Pfam PF13635 Domain of unknown function (DUF4143) 208 353 2.3E-15 T 22-04-2016 IPR025420 Domain of unknown function DUF4143 L21SP4_RS10730 dccc37591efc778627497fbf06a7379a 397 SUPERFAMILY SSF52540 8 189 1.32E-17 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS02035 7c2edf08d662ab9f04837f99e7cb7347 304 TIGRFAM TIGR02494 PFLE_PFLC: glycyl-radical enzyme activating protein 10 300 4.1E-104 T 22-04-2016 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 L21SP4_RS02035 7c2edf08d662ab9f04837f99e7cb7347 304 PIRSF PIRSF000371 1 304 1.3E-96 T 22-04-2016 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 L21SP4_RS02035 7c2edf08d662ab9f04837f99e7cb7347 304 PANTHER PTHR30352:SF4 108 301 1.2E-79 T 22-04-2016 L21SP4_RS02035 7c2edf08d662ab9f04837f99e7cb7347 304 PANTHER PTHR30352:SF4 1 62 1.2E-79 T 22-04-2016 L21SP4_RS02035 7c2edf08d662ab9f04837f99e7cb7347 304 Pfam PF13353 4Fe-4S single cluster domain 20 175 4.5E-14 T 22-04-2016 L21SP4_RS02035 7c2edf08d662ab9f04837f99e7cb7347 304 Pfam PF04055 Radical SAM superfamily 28 243 2.7E-31 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 L21SP4_RS02035 7c2edf08d662ab9f04837f99e7cb7347 304 Gene3D G3DSA:3.30.70.20 54 118 1.1E-15 T 22-04-2016 L21SP4_RS02035 7c2edf08d662ab9f04837f99e7cb7347 304 PANTHER PTHR30352 108 301 1.2E-79 T 22-04-2016 L21SP4_RS02035 7c2edf08d662ab9f04837f99e7cb7347 304 PANTHER PTHR30352 1 62 1.2E-79 T 22-04-2016 L21SP4_RS02035 7c2edf08d662ab9f04837f99e7cb7347 304 ProSitePatterns PS01087 Radical activating enzymes signature. 21 42 - T 22-04-2016 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 L21SP4_RS02035 7c2edf08d662ab9f04837f99e7cb7347 304 SUPERFAMILY SSF54862 18 115 2.93E-18 T 22-04-2016 L21SP4_RS02035 7c2edf08d662ab9f04837f99e7cb7347 304 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 90 101 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site L21SP4_RS02035 7c2edf08d662ab9f04837f99e7cb7347 304 SUPERFAMILY SSF102114 100 283 1.37E-22 T 22-04-2016 L21SP4_RS02035 7c2edf08d662ab9f04837f99e7cb7347 304 Gene3D G3DSA:3.80.30.10 130 303 1.1E-51 T 22-04-2016 L21SP4_RS05645 ce363159b8c7132d0611307e35511608 167 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 6 136 8.7E-32 T 22-04-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 L21SP4_RS05645 ce363159b8c7132d0611307e35511608 167 PANTHER PTHR20941 1 154 7.6E-44 T 22-04-2016 L21SP4_RS05645 ce363159b8c7132d0611307e35511608 167 SUPERFAMILY SSF55083 3 156 7.98E-41 T 22-04-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 L21SP4_RS05645 ce363159b8c7132d0611307e35511608 167 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 5 136 2.2E-30 T 22-04-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 L21SP4_RS05645 ce363159b8c7132d0611307e35511608 167 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 91 102 - T 22-04-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 L21SP4_RS05645 ce363159b8c7132d0611307e35511608 167 Gene3D G3DSA:3.30.70.560 3 156 5.3E-45 T 22-04-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 L21SP4_RS11805 d028fa5908c88fbaecf82375cc210a32 840 Gene3D G3DSA:2.115.10.20 21 124 1.7E-6 T 22-04-2016 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP4_RS11805 d028fa5908c88fbaecf82375cc210a32 840 SUPERFAMILY SSF49785 355 486 2.06E-12 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS11805 d028fa5908c88fbaecf82375cc210a32 840 Pfam PF00754 F5/8 type C domain 366 479 1.8E-7 T 22-04-2016 IPR000421 Coagulation factor 5/8 C-terminal domain L21SP4_RS11805 d028fa5908c88fbaecf82375cc210a32 840 SUPERFAMILY SSF75005 15 304 1.06E-23 T 22-04-2016 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP4_RS11805 d028fa5908c88fbaecf82375cc210a32 840 Gene3D G3DSA:2.60.120.260 350 510 1.1E-12 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS00620 285dbe9564ce68fd33aa707da3af7645 187 Gene3D G3DSA:3.40.50.300 16 56 5.0E-10 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS00620 285dbe9564ce68fd33aa707da3af7645 187 Pfam PF13476 AAA domain 19 48 1.5E-8 T 22-04-2016 L21SP4_RS00620 285dbe9564ce68fd33aa707da3af7645 187 SUPERFAMILY SSF52540 2 158 1.97E-20 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS00620 285dbe9564ce68fd33aa707da3af7645 187 SMART SM00382 24 166 4.3E-7 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS00620 285dbe9564ce68fd33aa707da3af7645 187 Gene3D G3DSA:3.40.50.300 94 158 6.3E-10 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS02675 c9172988cb739c55f0ece63cfa3d9ec2 141 Pfam PF13279 Thioesterase-like superfamily 20 136 4.8E-20 T 22-04-2016 L21SP4_RS02675 c9172988cb739c55f0ece63cfa3d9ec2 141 PANTHER PTHR31793 12 138 7.2E-29 T 22-04-2016 L21SP4_RS02675 c9172988cb739c55f0ece63cfa3d9ec2 141 Gene3D G3DSA:3.10.129.10 9 138 4.7E-32 T 22-04-2016 IPR029069 HotDog domain L21SP4_RS02675 c9172988cb739c55f0ece63cfa3d9ec2 141 SUPERFAMILY SSF54637 7 137 1.43E-32 T 22-04-2016 IPR029069 HotDog domain L21SP4_RS03060 738c5b43e7c90dc6b374110fd3da8e95 192 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 131 165 5.8E-9 T 22-04-2016 IPR001451 Hexapeptide repeat L21SP4_RS03060 738c5b43e7c90dc6b374110fd3da8e95 192 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 139 167 - T 22-04-2016 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: REACT_17015 L21SP4_RS03060 738c5b43e7c90dc6b374110fd3da8e95 192 PANTHER PTHR23416:SF58 40 192 1.1E-33 T 22-04-2016 L21SP4_RS03060 738c5b43e7c90dc6b374110fd3da8e95 192 SUPERFAMILY SSF51161 40 183 1.07E-33 T 22-04-2016 IPR011004 Trimeric LpxA-like L21SP4_RS03060 738c5b43e7c90dc6b374110fd3da8e95 192 Gene3D G3DSA:2.160.10.10 39 188 4.4E-37 T 22-04-2016 L21SP4_RS03060 738c5b43e7c90dc6b374110fd3da8e95 192 PANTHER PTHR23416 40 192 1.1E-33 T 22-04-2016 L21SP4_RS09085 7af4f96698c9251441f4b6f2c9ea3cb1 470 PRINTS PR00149 Fumarate lyase superfamily signature 277 304 2.8E-26 T 22-04-2016 IPR000362 Fumarate lyase family L21SP4_RS09085 7af4f96698c9251441f4b6f2c9ea3cb1 470 PRINTS PR00149 Fumarate lyase superfamily signature 186 204 2.8E-26 T 22-04-2016 IPR000362 Fumarate lyase family L21SP4_RS09085 7af4f96698c9251441f4b6f2c9ea3cb1 470 PRINTS PR00149 Fumarate lyase superfamily signature 318 334 2.8E-26 T 22-04-2016 IPR000362 Fumarate lyase family L21SP4_RS09085 7af4f96698c9251441f4b6f2c9ea3cb1 470 PRINTS PR00149 Fumarate lyase superfamily signature 141 159 2.8E-26 T 22-04-2016 IPR000362 Fumarate lyase family L21SP4_RS09085 7af4f96698c9251441f4b6f2c9ea3cb1 470 Gene3D G3DSA:1.20.200.10 146 403 2.0E-67 T 22-04-2016 L21SP4_RS09085 7af4f96698c9251441f4b6f2c9ea3cb1 470 SUPERFAMILY SSF48557 11 456 1.73E-109 T 22-04-2016 IPR008948 L-Aspartase-like GO:0003824 L21SP4_RS09085 7af4f96698c9251441f4b6f2c9ea3cb1 470 Gene3D G3DSA:1.10.275.10 10 145 6.0E-48 T 22-04-2016 IPR024083 Fumarase/histidase, N-terminal L21SP4_RS09085 7af4f96698c9251441f4b6f2c9ea3cb1 470 PANTHER PTHR11444:SF24 1 426 6.1E-160 T 22-04-2016 L21SP4_RS09085 7af4f96698c9251441f4b6f2c9ea3cb1 470 PANTHER PTHR11444 1 426 6.1E-160 T 22-04-2016 IPR000362 Fumarate lyase family L21SP4_RS09085 7af4f96698c9251441f4b6f2c9ea3cb1 470 ProSitePatterns PS00163 Fumarate lyases signature. 318 327 - T 22-04-2016 IPR020557 Fumarate lyase, conserved site GO:0003824 L21SP4_RS09085 7af4f96698c9251441f4b6f2c9ea3cb1 470 Pfam PF00206 Lyase 20 342 7.4E-78 T 22-04-2016 IPR022761 Fumarate lyase, N-terminal L21SP4_RS09885 0e912bbd9e4135aa07d8edfe4f9c2794 347 SUPERFAMILY SSF51717 94 306 9.81E-52 T 22-04-2016 IPR011005 Dihydropteroate synthase-like GO:0044237 L21SP4_RS09885 0e912bbd9e4135aa07d8edfe4f9c2794 347 Pfam PF00809 Pterin binding enzyme 97 302 5.0E-25 T 22-04-2016 IPR000489 Pterin-binding domain GO:0042558 L21SP4_RS09885 0e912bbd9e4135aa07d8edfe4f9c2794 347 Gene3D G3DSA:3.20.20.20 95 343 6.5E-54 T 22-04-2016 IPR000489 Pterin-binding domain GO:0042558 L21SP4_RS11585 21b5c41f631d58fc80a4c2e777352370 459 Gene3D G3DSA:1.25.40.10 334 456 1.1E-16 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS11585 21b5c41f631d58fc80a4c2e777352370 459 PANTHER PTHR23083 90 178 1.5E-24 T 22-04-2016 L21SP4_RS11585 21b5c41f631d58fc80a4c2e777352370 459 PANTHER PTHR23083 336 448 1.5E-24 T 22-04-2016 L21SP4_RS11585 21b5c41f631d58fc80a4c2e777352370 459 PANTHER PTHR23083 10 61 1.5E-24 T 22-04-2016 L21SP4_RS11585 21b5c41f631d58fc80a4c2e777352370 459 PANTHER PTHR23083 249 278 1.5E-24 T 22-04-2016 L21SP4_RS11585 21b5c41f631d58fc80a4c2e777352370 459 SUPERFAMILY SSF48452 232 279 1.76E-17 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS11585 21b5c41f631d58fc80a4c2e777352370 459 SUPERFAMILY SSF48452 93 181 1.76E-17 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS11585 21b5c41f631d58fc80a4c2e777352370 459 SUPERFAMILY SSF48452 10 63 1.76E-17 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS11585 21b5c41f631d58fc80a4c2e777352370 459 Pfam PF13432 Tetratricopeptide repeat 344 405 9.3E-8 T 22-04-2016 L21SP4_RS11585 21b5c41f631d58fc80a4c2e777352370 459 SUPERFAMILY SSF48452 239 286 1.9E-20 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS11585 21b5c41f631d58fc80a4c2e777352370 459 SUPERFAMILY SSF48452 329 439 1.9E-20 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS11585 21b5c41f631d58fc80a4c2e777352370 459 Pfam PF13181 Tetratricopeptide repeat 154 178 0.11 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS11585 21b5c41f631d58fc80a4c2e777352370 459 SMART SM00028 13 46 14.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS11585 21b5c41f631d58fc80a4c2e777352370 459 SMART SM00028 412 445 30.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS11585 21b5c41f631d58fc80a4c2e777352370 459 SMART SM00028 145 178 44.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS11585 21b5c41f631d58fc80a4c2e777352370 459 SMART SM00028 374 407 1.3 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS11585 21b5c41f631d58fc80a4c2e777352370 459 SMART SM00028 340 373 28.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS11585 21b5c41f631d58fc80a4c2e777352370 459 SMART SM00028 249 282 80.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS11585 21b5c41f631d58fc80a4c2e777352370 459 Gene3D G3DSA:1.25.40.10 213 279 3.5E-9 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS11585 21b5c41f631d58fc80a4c2e777352370 459 Gene3D G3DSA:1.25.40.10 7 182 3.8E-12 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS08560 800cd3a1a40deaa46fa60d21b6967210 398 Gene3D G3DSA:3.40.50.450 2 224 1.6E-51 T 22-04-2016 L21SP4_RS08560 800cd3a1a40deaa46fa60d21b6967210 398 PANTHER PTHR13697 84 377 4.2E-54 T 22-04-2016 L21SP4_RS08560 800cd3a1a40deaa46fa60d21b6967210 398 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 93 109 6.7E-5 T 22-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 L21SP4_RS08560 800cd3a1a40deaa46fa60d21b6967210 398 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 222 234 6.7E-5 T 22-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 L21SP4_RS08560 800cd3a1a40deaa46fa60d21b6967210 398 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 126 143 6.7E-5 T 22-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 L21SP4_RS08560 800cd3a1a40deaa46fa60d21b6967210 398 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 3 22 6.7E-5 T 22-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 L21SP4_RS08560 800cd3a1a40deaa46fa60d21b6967210 398 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 164 180 6.7E-5 T 22-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 L21SP4_RS08560 800cd3a1a40deaa46fa60d21b6967210 398 PIRSF PIRSF036483 1 397 2.8E-134 T 22-04-2016 IPR011404 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase, XF0274 GO:0006096|GO:0047334 KEGG: 00051+2.7.1.90|MetaCyc: PWY-1042|UniPathway: UPA00109 L21SP4_RS08560 800cd3a1a40deaa46fa60d21b6967210 398 PANTHER PTHR13697:SF19 84 377 4.2E-54 T 22-04-2016 L21SP4_RS08560 800cd3a1a40deaa46fa60d21b6967210 398 SUPERFAMILY SSF53784 2 382 1.27E-89 T 22-04-2016 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 L21SP4_RS08560 800cd3a1a40deaa46fa60d21b6967210 398 Hamap MF_01978 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase [pfp]. 1 392 38.374 T 22-04-2016 IPR011404 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase, XF0274 GO:0006096|GO:0047334 KEGG: 00051+2.7.1.90|MetaCyc: PWY-1042|UniPathway: UPA00109 L21SP4_RS08560 800cd3a1a40deaa46fa60d21b6967210 398 Pfam PF00365 Phosphofructokinase 3 317 2.4E-47 T 22-04-2016 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 L21SP4_RS09430 548d90eff089c4a9845348c4382737de 989 Gene3D G3DSA:3.30.379.10 337 427 2.1E-6 T 22-04-2016 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like L21SP4_RS09430 548d90eff089c4a9845348c4382737de 989 Pfam PF15979 Glycosyl hydrolase family 115 457 785 1.0E-68 T 22-04-2016 IPR031924 Glycosyl hydrolase family 115 L21SP4_RS09430 548d90eff089c4a9845348c4382737de 989 SUPERFAMILY SSF51445 509 630 6.55E-5 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily L21SP4_RS09430 548d90eff089c4a9845348c4382737de 989 PANTHER PTHR37842 389 785 4.0E-50 T 22-04-2016 L21SP4_RS09430 548d90eff089c4a9845348c4382737de 989 SUPERFAMILY SSF55545 337 426 7.59E-6 T 22-04-2016 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like L21SP4_RS02265 bea2d275ea68c6e4549362bb3af6bf87 182 Pfam PF13338 Transcriptional regulator, AbiEi antitoxin 43 105 3.9E-8 T 22-04-2016 IPR025159 Transcriptional regulator, AbiEi antitoxin L21SP4_RS02255 f935fb7af4f761a28f7544a6fb1612f7 805 Gene3D G3DSA:1.10.238.10 25 69 4.1E-5 T 22-04-2016 IPR011992 EF-hand domain pair L21SP4_RS02255 f935fb7af4f761a28f7544a6fb1612f7 805 Pfam PF13202 EF hand 51 69 0.0017 T 22-04-2016 IPR002048 EF-hand domain GO:0005509 L21SP4_RS02255 f935fb7af4f761a28f7544a6fb1612f7 805 Pfam PF13202 EF hand 29 47 5.0E-4 T 22-04-2016 IPR002048 EF-hand domain GO:0005509 L21SP4_RS02255 f935fb7af4f761a28f7544a6fb1612f7 805 PANTHER PTHR23024 117 344 9.6E-25 T 22-04-2016 L21SP4_RS02255 f935fb7af4f761a28f7544a6fb1612f7 805 SUPERFAMILY SSF47473 28 69 5.6E-6 T 22-04-2016 IPR011992 EF-hand domain pair L21SP4_RS02255 f935fb7af4f761a28f7544a6fb1612f7 805 ProSitePatterns PS00018 EF-hand calcium-binding domain. 35 47 - T 22-04-2016 IPR018247 EF-Hand 1, calcium-binding site L21SP4_RS02255 f935fb7af4f761a28f7544a6fb1612f7 805 ProSitePatterns PS00018 EF-hand calcium-binding domain. 57 69 - T 22-04-2016 IPR018247 EF-Hand 1, calcium-binding site L21SP4_RS02255 f935fb7af4f761a28f7544a6fb1612f7 805 Gene3D G3DSA:3.40.50.1820 99 347 9.1E-46 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold L21SP4_RS02255 f935fb7af4f761a28f7544a6fb1612f7 805 Pfam PF00135 Carboxylesterase family 114 228 5.2E-18 T 22-04-2016 IPR002018 Carboxylesterase, type B L21SP4_RS02255 f935fb7af4f761a28f7544a6fb1612f7 805 SUPERFAMILY SSF53474 98 351 1.54E-42 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold L21SP4_RS12070 85da8d666ca69dd788da2f92b53889e4 328 Gene3D G3DSA:3.40.50.1000 177 302 9.4E-16 T 22-04-2016 IPR023214 HAD-like domain L21SP4_RS12070 85da8d666ca69dd788da2f92b53889e4 328 Gene3D G3DSA:3.40.50.1000 79 99 9.4E-16 T 22-04-2016 IPR023214 HAD-like domain L21SP4_RS12070 85da8d666ca69dd788da2f92b53889e4 328 Pfam PF13419 Haloacid dehalogenase-like hydrolase 83 210 1.3E-7 T 22-04-2016 IPR023214 HAD-like domain L21SP4_RS12070 85da8d666ca69dd788da2f92b53889e4 328 SUPERFAMILY SSF56784 80 301 2.07E-20 T 22-04-2016 IPR023214 HAD-like domain L21SP4_RS12070 85da8d666ca69dd788da2f92b53889e4 328 PANTHER PTHR18901 79 302 2.9E-13 T 22-04-2016 L21SP4_RS01140 87203c3b47e1883d8bbd1365c8eeff4d 265 PANTHER PTHR30505 1 154 1.4E-17 T 22-04-2016 L21SP4_RS01140 87203c3b47e1883d8bbd1365c8eeff4d 265 SUPERFAMILY SSF55804 3 143 1.57E-22 T 22-04-2016 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: REACT_15518 L21SP4_RS01140 87203c3b47e1883d8bbd1365c8eeff4d 265 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 3 143 1.3E-19 T 22-04-2016 IPR002178 PTS EIIA type-2 domain KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- L21SP4_RS01140 87203c3b47e1883d8bbd1365c8eeff4d 265 Gene3D G3DSA:3.40.930.10 2 144 9.7E-24 T 22-04-2016 IPR002178 PTS EIIA type-2 domain KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- L21SP4_RS09875 9b1be0fc0f94831f46c6b7d06dc315a0 730 SUPERFAMILY SSF53756 35 458 3.73E-69 T 22-04-2016 L21SP4_RS09875 9b1be0fc0f94831f46c6b7d06dc315a0 730 PANTHER PTHR12526 17 453 2.0E-154 T 22-04-2016 L21SP4_RS09875 9b1be0fc0f94831f46c6b7d06dc315a0 730 TIGRFAM TIGR02471 sucr_syn_bact_C: sucrose-phosphate synthase, sucrose phosphatase-like domain 480 715 4.0E-97 T 22-04-2016 IPR012821 Sucrose phosphate synthase, sucrose phosphatase-like domain L21SP4_RS09875 9b1be0fc0f94831f46c6b7d06dc315a0 730 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 481 672 2.8E-13 T 22-04-2016 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: REACT_17015 L21SP4_RS09875 9b1be0fc0f94831f46c6b7d06dc315a0 730 Pfam PF13439 Glycosyltransferase Family 4 42 238 2.5E-18 T 22-04-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain L21SP4_RS09875 9b1be0fc0f94831f46c6b7d06dc315a0 730 Gene3D G3DSA:3.40.50.2000 223 433 7.2E-25 T 22-04-2016 L21SP4_RS09875 9b1be0fc0f94831f46c6b7d06dc315a0 730 PANTHER PTHR12526:SF360 17 453 2.0E-154 T 22-04-2016 L21SP4_RS09875 9b1be0fc0f94831f46c6b7d06dc315a0 730 SUPERFAMILY SSF56784 479 686 1.21E-29 T 22-04-2016 IPR023214 HAD-like domain L21SP4_RS09875 9b1be0fc0f94831f46c6b7d06dc315a0 730 Gene3D G3DSA:3.40.50.1000 632 714 2.8E-27 T 22-04-2016 IPR023214 HAD-like domain L21SP4_RS09875 9b1be0fc0f94831f46c6b7d06dc315a0 730 Gene3D G3DSA:3.40.50.1000 479 556 2.8E-27 T 22-04-2016 IPR023214 HAD-like domain L21SP4_RS09875 9b1be0fc0f94831f46c6b7d06dc315a0 730 Pfam PF00534 Glycosyl transferases group 1 258 434 2.8E-27 T 22-04-2016 IPR001296 Glycosyl transferase, family 1 L21SP4_RS09875 9b1be0fc0f94831f46c6b7d06dc315a0 730 TIGRFAM TIGR02472 sucr_P_syn_N: sucrose-phosphate synthase, putative, glycosyltransferase domain 17 453 1.6E-208 T 22-04-2016 IPR012822 Sucrose-phosphate synthase, glycosyltransferase domain L21SP4_RS09875 9b1be0fc0f94831f46c6b7d06dc315a0 730 Gene3D G3DSA:3.90.1070.10 566 631 2.1E-21 T 22-04-2016 L21SP4_RS09875 9b1be0fc0f94831f46c6b7d06dc315a0 730 Pfam PF05116 Sucrose-6F-phosphate phosphohydrolase 479 715 1.4E-80 T 22-04-2016 IPR006380 Sucrose-phosphatase, N-terminal L21SP4_RS11330 4127a2b8d0f5d86597b1672797da3a8c 125 SMART SM00670 4 116 6.4E-4 T 22-04-2016 IPR002716 PIN domain L21SP4_RS11330 4127a2b8d0f5d86597b1672797da3a8c 125 SUPERFAMILY SSF88723 4 125 3.08E-14 T 22-04-2016 IPR029060 PIN domain-like L21SP4_RS11330 4127a2b8d0f5d86597b1672797da3a8c 125 Pfam PF01850 PIN domain 6 114 1.3E-9 T 22-04-2016 IPR002716 PIN domain L21SP4_RS11330 4127a2b8d0f5d86597b1672797da3a8c 125 Gene3D G3DSA:3.40.50.1010 4 114 5.9E-14 T 22-04-2016 IPR029060 PIN domain-like L21SP4_RS02900 5add63436da35033fdd6860e7049fc88 296 PANTHER PTHR24322 151 183 1.3E-42 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS02900 5add63436da35033fdd6860e7049fc88 296 PANTHER PTHR24322 13 135 1.3E-42 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS02900 5add63436da35033fdd6860e7049fc88 296 Gene3D G3DSA:3.40.50.720 9 252 7.2E-58 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS02900 5add63436da35033fdd6860e7049fc88 296 Pfam PF00106 short chain dehydrogenase 9 193 1.1E-39 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS02900 5add63436da35033fdd6860e7049fc88 296 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 138 166 - T 22-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 L21SP4_RS02900 5add63436da35033fdd6860e7049fc88 296 SUPERFAMILY SSF51735 9 252 6.51E-56 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS02900 5add63436da35033fdd6860e7049fc88 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 4.2E-18 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS02900 5add63436da35033fdd6860e7049fc88 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 4.2E-18 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS02900 5add63436da35033fdd6860e7049fc88 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 4.2E-18 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS02900 5add63436da35033fdd6860e7049fc88 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 4.2E-18 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS02900 5add63436da35033fdd6860e7049fc88 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 4.2E-18 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS03605 eff852411970d73e24e48b36aeeb334a 256 SMART SM00382 26 214 2.1E-9 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS03605 eff852411970d73e24e48b36aeeb334a 256 PANTHER PTHR24220 3 240 2.7E-101 T 22-04-2016 L21SP4_RS03605 eff852411970d73e24e48b36aeeb334a 256 Gene3D G3DSA:3.40.50.300 1 237 7.2E-71 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS03605 eff852411970d73e24e48b36aeeb334a 256 Pfam PF00005 ABC transporter 17 166 1.3E-31 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 L21SP4_RS03605 eff852411970d73e24e48b36aeeb334a 256 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 L21SP4_RS03605 eff852411970d73e24e48b36aeeb334a 256 PANTHER PTHR24220:SF567 3 240 2.7E-101 T 22-04-2016 L21SP4_RS03605 eff852411970d73e24e48b36aeeb334a 256 SUPERFAMILY SSF52540 1 233 9.44E-64 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS05075 00ac94202344a2fb1406992b134293b4 227 PANTHER PTHR11749 5 222 4.7E-79 T 22-04-2016 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 L21SP4_RS05075 00ac94202344a2fb1406992b134293b4 227 Gene3D G3DSA:3.20.20.70 6 222 5.5E-67 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP4_RS05075 00ac94202344a2fb1406992b134293b4 227 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 36 50 - T 22-04-2016 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 L21SP4_RS05075 00ac94202344a2fb1406992b134293b4 227 Pfam PF00834 Ribulose-phosphate 3 epimerase family 9 203 1.0E-53 T 22-04-2016 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 L21SP4_RS05075 00ac94202344a2fb1406992b134293b4 227 SUPERFAMILY SSF51366 7 220 5.14E-52 T 22-04-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 L21SP4_RS05075 00ac94202344a2fb1406992b134293b4 227 PANTHER PTHR11749:SF3 5 222 4.7E-79 T 22-04-2016 L21SP4_RS09860 59ae49493ba78cc3aa266bd49034fc81 436 SUPERFAMILY SSF55347 187 388 7.41E-13 T 22-04-2016 L21SP4_RS09860 59ae49493ba78cc3aa266bd49034fc81 436 Gene3D G3DSA:3.40.50.720 42 197 3.4E-43 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS09860 59ae49493ba78cc3aa266bd49034fc81 436 PANTHER PTHR22604:SF122 3 419 2.7E-94 T 22-04-2016 L21SP4_RS09860 59ae49493ba78cc3aa266bd49034fc81 436 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 8 33 7.0E-4 T 22-04-2016 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal L21SP4_RS09860 59ae49493ba78cc3aa266bd49034fc81 436 SUPERFAMILY SSF51735 39 210 7.48E-43 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS09860 59ae49493ba78cc3aa266bd49034fc81 436 Gene3D G3DSA:3.30.360.10 198 410 2.8E-13 T 22-04-2016 L21SP4_RS09860 59ae49493ba78cc3aa266bd49034fc81 436 PANTHER PTHR22604 3 419 2.7E-94 T 22-04-2016 L21SP4_RS09860 59ae49493ba78cc3aa266bd49034fc81 436 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 50 179 7.4E-19 T 22-04-2016 IPR000683 Oxidoreductase, N-terminal GO:0016491 L21SP4_RS06330 ebf79db51fc25db30f69c74e86e77858 1510 PANTHER PTHR11938:SF1 10 1497 0.0 T 22-04-2016 L21SP4_RS06330 ebf79db51fc25db30f69c74e86e77858 1510 Pfam PF04898 Glutamate synthase central domain 467 752 2.2E-110 T 22-04-2016 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 UniPathway: UPA00045 L21SP4_RS06330 ebf79db51fc25db30f69c74e86e77858 1510 Gene3D G3DSA:3.60.20.10 21 448 2.0E-176 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal L21SP4_RS06330 ebf79db51fc25db30f69c74e86e77858 1510 Pfam PF01645 Conserved region in glutamate synthase 815 1181 2.4E-156 T 22-04-2016 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 L21SP4_RS06330 ebf79db51fc25db30f69c74e86e77858 1510 Gene3D G3DSA:3.20.20.70 458 801 8.9E-106 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP4_RS06330 ebf79db51fc25db30f69c74e86e77858 1510 Gene3D G3DSA:3.20.20.70 810 1216 1.7E-181 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP4_RS06330 ebf79db51fc25db30f69c74e86e77858 1510 SUPERFAMILY SSF56235 21 444 5.71E-151 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal L21SP4_RS06330 ebf79db51fc25db30f69c74e86e77858 1510 Pfam PF00310 Glutamine amidotransferases class-II 21 440 1.0E-176 T 22-04-2016 IPR017932 Glutamine amidotransferase type 2 domain L21SP4_RS06330 ebf79db51fc25db30f69c74e86e77858 1510 SUPERFAMILY SSF69336 1229 1495 3.27E-97 T 22-04-2016 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 L21SP4_RS06330 ebf79db51fc25db30f69c74e86e77858 1510 SUPERFAMILY SSF51395 457 1217 3.7E-260 T 22-04-2016 L21SP4_RS06330 ebf79db51fc25db30f69c74e86e77858 1510 PANTHER PTHR11938 10 1497 0.0 T 22-04-2016 L21SP4_RS06330 ebf79db51fc25db30f69c74e86e77858 1510 Pfam PF01493 GXGXG motif 1260 1447 9.9E-82 T 22-04-2016 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 L21SP4_RS06330 ebf79db51fc25db30f69c74e86e77858 1510 Gene3D G3DSA:2.160.20.60 1241 1504 1.9E-104 T 22-04-2016 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 L21SP4_RS07455 c621558885a1fe62600e36b5039aa689 140 Pfam PF00239 Resolvase, N terminal domain 8 131 6.4E-23 T 22-04-2016 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 L21SP4_RS07455 c621558885a1fe62600e36b5039aa689 140 PANTHER PTHR30461:SF3 6 113 1.9E-14 T 22-04-2016 L21SP4_RS07455 c621558885a1fe62600e36b5039aa689 140 Gene3D G3DSA:3.40.50.1390 6 132 1.1E-22 T 22-04-2016 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 L21SP4_RS07455 c621558885a1fe62600e36b5039aa689 140 PANTHER PTHR30461 6 113 1.9E-14 T 22-04-2016 L21SP4_RS07455 c621558885a1fe62600e36b5039aa689 140 SMART SM00857 7 137 1.9E-22 T 22-04-2016 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 L21SP4_RS07455 c621558885a1fe62600e36b5039aa689 140 SUPERFAMILY SSF53041 6 132 1.19E-23 T 22-04-2016 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 L21SP4_RS02775 397ebe4f559980bccf01584ababf341b 266 PANTHER PTHR11019 31 265 7.2E-25 T 22-04-2016 L21SP4_RS02775 397ebe4f559980bccf01584ababf341b 266 Gene3D G3DSA:2.60.120.280 27 153 2.9E-10 T 22-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 L21SP4_RS02775 397ebe4f559980bccf01584ababf341b 266 Gene3D G3DSA:1.10.10.60 220 265 7.3E-14 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS02775 397ebe4f559980bccf01584ababf341b 266 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 234 249 1.3E-6 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 L21SP4_RS02775 397ebe4f559980bccf01584ababf341b 266 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 249 265 1.3E-6 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 L21SP4_RS02775 397ebe4f559980bccf01584ababf341b 266 SMART SM00342 182 265 7.0E-27 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP4_RS02775 397ebe4f559980bccf01584ababf341b 266 Gene3D G3DSA:1.10.10.60 166 219 8.8E-12 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS02775 397ebe4f559980bccf01584ababf341b 266 Pfam PF02311 AraC-like ligand binding domain 29 89 2.2E-5 T 22-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 L21SP4_RS02775 397ebe4f559980bccf01584ababf341b 266 Pfam PF12833 Helix-turn-helix domain 188 265 7.3E-21 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP4_RS02775 397ebe4f559980bccf01584ababf341b 266 SUPERFAMILY SSF51215 20 153 6.67E-13 T 22-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 L21SP4_RS02775 397ebe4f559980bccf01584ababf341b 266 SUPERFAMILY SSF46689 219 265 4.35E-11 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS02775 397ebe4f559980bccf01584ababf341b 266 SUPERFAMILY SSF46689 166 214 2.33E-6 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS11770 0761095a16dc44e48ff860302e93c96e 117 SUPERFAMILY SSF88723 35 105 3.08E-6 T 22-04-2016 IPR029060 PIN domain-like L21SP4_RS07700 881e3b75b4a48b6a166244f0f0e0f29c 152 Pfam PF01475 Ferric uptake regulator family 23 143 1.2E-25 T 22-04-2016 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 L21SP4_RS07700 881e3b75b4a48b6a166244f0f0e0f29c 152 PANTHER PTHR33202 19 152 2.0E-29 T 22-04-2016 L21SP4_RS07700 881e3b75b4a48b6a166244f0f0e0f29c 152 Gene3D G3DSA:1.10.10.10 19 94 8.6E-17 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS07700 881e3b75b4a48b6a166244f0f0e0f29c 152 SUPERFAMILY SSF46785 19 148 3.09E-30 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS11870 2e6bfa03bec355c4c29a56973db32d73 451 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 20 424 8.1E-133 T 22-04-2016 IPR004681 TRAP transporter permease protein GO:0016021 L21SP4_RS11870 2e6bfa03bec355c4c29a56973db32d73 451 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 10 417 3.8E-116 T 22-04-2016 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit L21SP4_RS11870 2e6bfa03bec355c4c29a56973db32d73 451 PANTHER PTHR33362:SF2 3 424 9.6E-172 T 22-04-2016 L21SP4_RS11870 2e6bfa03bec355c4c29a56973db32d73 451 PANTHER PTHR33362 3 424 9.6E-172 T 22-04-2016 L21SP4_RS11870 2e6bfa03bec355c4c29a56973db32d73 451 PIRSF PIRSF006066 3 429 1.9E-156 T 22-04-2016 IPR004681 TRAP transporter permease protein GO:0016021 L21SP4_RS04160 936416d31884cf3be5dc7df86b4948c8 367 SUPERFAMILY SSF50182 181 246 6.87E-16 T 22-04-2016 IPR010920 LSM domain L21SP4_RS04160 936416d31884cf3be5dc7df86b4948c8 367 Gene3D G3DSA:3.30.70.100 250 340 1.3E-15 T 22-04-2016 L21SP4_RS04160 936416d31884cf3be5dc7df86b4948c8 367 SUPERFAMILY SSF82689 249 352 1.57E-22 T 22-04-2016 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 L21SP4_RS04160 936416d31884cf3be5dc7df86b4948c8 367 Gene3D G3DSA:2.30.30.60 197 245 2.3E-16 T 22-04-2016 L21SP4_RS04160 936416d31884cf3be5dc7df86b4948c8 367 Pfam PF00924 Mechanosensitive ion channel 141 342 2.2E-49 T 22-04-2016 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 L21SP4_RS04160 936416d31884cf3be5dc7df86b4948c8 367 PANTHER PTHR30566:SF5 35 356 3.3E-67 T 22-04-2016 L21SP4_RS04160 936416d31884cf3be5dc7df86b4948c8 367 PANTHER PTHR30566 35 356 3.3E-67 T 22-04-2016 L21SP4_RS04160 936416d31884cf3be5dc7df86b4948c8 367 SUPERFAMILY SSF82861 94 180 1.83E-10 T 22-04-2016 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 L21SP4_RS07100 28ccbaf303260d1fb75623d86c76def5 418 SMART SM00382 113 274 6.9E-11 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS07100 28ccbaf303260d1fb75623d86c76def5 418 SUPERFAMILY SSF57716 8 42 1.57E-9 T 22-04-2016 L21SP4_RS07100 28ccbaf303260d1fb75623d86c76def5 418 SUPERFAMILY SSF52540 65 402 1.84E-72 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS07100 28ccbaf303260d1fb75623d86c76def5 418 Gene3D G3DSA:1.10.8.60 314 408 1.2E-34 T 22-04-2016 L21SP4_RS07100 28ccbaf303260d1fb75623d86c76def5 418 Gene3D G3DSA:3.40.50.300 292 308 9.2E-48 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS07100 28ccbaf303260d1fb75623d86c76def5 418 Gene3D G3DSA:3.40.50.300 67 255 9.2E-48 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS07100 28ccbaf303260d1fb75623d86c76def5 418 SMART SM01086 315 410 3.7E-29 T 22-04-2016 IPR019489 Clp ATPase, C-terminal L21SP4_RS07100 28ccbaf303260d1fb75623d86c76def5 418 SMART SM00994 6 45 7.2E-18 T 22-04-2016 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 L21SP4_RS07100 28ccbaf303260d1fb75623d86c76def5 418 Pfam PF06689 ClpX C4-type zinc finger 8 43 1.4E-16 T 22-04-2016 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 L21SP4_RS07100 28ccbaf303260d1fb75623d86c76def5 418 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 6 407 2.0E-183 T 22-04-2016 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 L21SP4_RS07100 28ccbaf303260d1fb75623d86c76def5 418 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 315 392 6.4E-15 T 22-04-2016 IPR019489 Clp ATPase, C-terminal L21SP4_RS07100 28ccbaf303260d1fb75623d86c76def5 418 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 2 413 49.047 T 22-04-2016 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 L21SP4_RS07100 28ccbaf303260d1fb75623d86c76def5 418 Pfam PF07724 AAA domain (Cdc48 subfamily) 113 308 4.2E-46 T 22-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 L21SP4_RS07100 28ccbaf303260d1fb75623d86c76def5 418 PANTHER PTHR11262 8 411 7.3E-222 T 22-04-2016 L21SP4_RS08230 da6690f7886ff5ceb4dfcfe3655b3f35 260 SUPERFAMILY SSF46689 207 257 4.3E-13 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS08230 da6690f7886ff5ceb4dfcfe3655b3f35 260 SMART SM00342 170 254 1.7E-25 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP4_RS08230 da6690f7886ff5ceb4dfcfe3655b3f35 260 Gene3D G3DSA:1.10.10.60 153 207 8.4E-12 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS08230 da6690f7886ff5ceb4dfcfe3655b3f35 260 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 208 250 - T 22-04-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 L21SP4_RS08230 da6690f7886ff5ceb4dfcfe3655b3f35 260 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 238 254 5.8E-7 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 L21SP4_RS08230 da6690f7886ff5ceb4dfcfe3655b3f35 260 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 223 238 5.8E-7 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 L21SP4_RS08230 da6690f7886ff5ceb4dfcfe3655b3f35 260 Pfam PF07729 FCD domain 11 135 2.6E-10 T 22-04-2016 IPR011711 GntR, C-terminal L21SP4_RS08230 da6690f7886ff5ceb4dfcfe3655b3f35 260 PANTHER PTHR11019 77 259 3.4E-25 T 22-04-2016 L21SP4_RS08230 da6690f7886ff5ceb4dfcfe3655b3f35 260 Gene3D G3DSA:1.20.120.530 7 140 8.2E-12 T 22-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal L21SP4_RS08230 da6690f7886ff5ceb4dfcfe3655b3f35 260 Pfam PF12833 Helix-turn-helix domain 181 255 2.2E-21 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP4_RS08230 da6690f7886ff5ceb4dfcfe3655b3f35 260 SUPERFAMILY SSF48008 10 140 2.62E-13 T 22-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal L21SP4_RS08230 da6690f7886ff5ceb4dfcfe3655b3f35 260 SUPERFAMILY SSF46689 155 205 1.34E-6 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS08230 da6690f7886ff5ceb4dfcfe3655b3f35 260 Gene3D G3DSA:1.10.10.60 208 257 3.8E-17 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS08230 da6690f7886ff5ceb4dfcfe3655b3f35 260 SMART SM00895 9 136 3.1E-5 T 22-04-2016 IPR011711 GntR, C-terminal L21SP4_RS10430 4243ae51eb118f24a03cd92e25dc867a 300 PANTHER PTHR23083 118 259 8.1E-18 T 22-04-2016 L21SP4_RS10430 4243ae51eb118f24a03cd92e25dc867a 300 SUPERFAMILY SSF48452 113 245 5.18E-21 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS10430 4243ae51eb118f24a03cd92e25dc867a 300 SMART SM00028 108 141 0.63 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS10430 4243ae51eb118f24a03cd92e25dc867a 300 SMART SM00028 142 175 0.038 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS10430 4243ae51eb118f24a03cd92e25dc867a 300 SMART SM00028 215 248 20.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS10430 4243ae51eb118f24a03cd92e25dc867a 300 Pfam PF13414 TPR repeat 115 156 6.8E-11 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS10430 4243ae51eb118f24a03cd92e25dc867a 300 Gene3D G3DSA:1.25.40.10 113 260 1.3E-26 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS01745 0da59c7f39c62532b8b79346a5485ab1 591 PANTHER PTHR23083:SF401 80 210 2.6E-27 T 22-04-2016 L21SP4_RS01745 0da59c7f39c62532b8b79346a5485ab1 591 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 82 210 2.2E-6 T 22-04-2016 L21SP4_RS01745 0da59c7f39c62532b8b79346a5485ab1 591 PANTHER PTHR23083 80 210 2.6E-27 T 22-04-2016 L21SP4_RS07260 feea92c0a2ddf22eda5bb754d0ae4434 475 ProSitePatterns PS00523 Sulfatases signature 1. 83 95 - T 22-04-2016 IPR024607 Sulfatase, conserved site L21SP4_RS07260 feea92c0a2ddf22eda5bb754d0ae4434 475 Gene3D G3DSA:3.30.1120.10 356 468 3.5E-23 T 22-04-2016 L21SP4_RS07260 feea92c0a2ddf22eda5bb754d0ae4434 475 Pfam PF00884 Sulfatase 38 324 8.5E-59 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS07260 feea92c0a2ddf22eda5bb754d0ae4434 475 Pfam PF16347 Domain of unknown function (DUF4976) 415 458 4.7E-9 T 22-04-2016 IPR032506 Domain of unknown function DUF4976 L21SP4_RS07260 feea92c0a2ddf22eda5bb754d0ae4434 475 Gene3D G3DSA:3.40.720.10 35 343 2.7E-87 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS07260 feea92c0a2ddf22eda5bb754d0ae4434 475 SUPERFAMILY SSF53649 413 459 1.45E-115 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS07260 feea92c0a2ddf22eda5bb754d0ae4434 475 SUPERFAMILY SSF53649 36 383 1.45E-115 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS07260 feea92c0a2ddf22eda5bb754d0ae4434 475 PANTHER PTHR10342 10 459 1.7E-114 T 22-04-2016 L21SP4_RS00630 2d4584bc60b9b9ad1ae20bb3994805e6 555 Gene3D G3DSA:3.40.50.980 3 188 4.7E-35 T 22-04-2016 L21SP4_RS00630 2d4584bc60b9b9ad1ae20bb3994805e6 555 Pfam PF00501 AMP-binding enzyme 12 441 9.5E-102 T 22-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 L21SP4_RS00630 2d4584bc60b9b9ad1ae20bb3994805e6 555 Gene3D G3DSA:3.40.50.980 189 366 4.9E-37 T 22-04-2016 L21SP4_RS00630 2d4584bc60b9b9ad1ae20bb3994805e6 555 Gene3D G3DSA:3.30.300.30 440 550 7.3E-15 T 22-04-2016 L21SP4_RS00630 2d4584bc60b9b9ad1ae20bb3994805e6 555 PANTHER PTHR24096 3 549 6.2E-155 T 22-04-2016 L21SP4_RS00630 2d4584bc60b9b9ad1ae20bb3994805e6 555 ProSitePatterns PS00455 Putative AMP-binding domain signature. 182 193 - T 22-04-2016 IPR020845 AMP-binding, conserved site L21SP4_RS00630 2d4584bc60b9b9ad1ae20bb3994805e6 555 SUPERFAMILY SSF56801 4 550 7.85E-134 T 22-04-2016 L21SP4_RS00630 2d4584bc60b9b9ad1ae20bb3994805e6 555 Gene3D G3DSA:2.30.38.10 367 432 3.1E-22 T 22-04-2016 L21SP4_RS00630 2d4584bc60b9b9ad1ae20bb3994805e6 555 Pfam PF13193 AMP-binding enzyme C-terminal domain 452 546 5.4E-8 T 22-04-2016 IPR025110 AMP-binding enzyme C-terminal domain L21SP4_RS08915 2c39a6d326a33bc2f7f084c1e959f89f 387 SUPERFAMILY SSF50939 35 349 1.57E-17 T 22-04-2016 IPR011040 Sialidases L21SP4_RS08915 2c39a6d326a33bc2f7f084c1e959f89f 387 Gene3D G3DSA:2.120.10.10 34 351 5.5E-25 T 22-04-2016 IPR011040 Sialidases L21SP4_RS03560 10a2faf2de8c526feb2ae862519cfd0b 362 Gene3D G3DSA:1.10.40.60 125 208 3.6E-11 T 22-04-2016 L21SP4_RS03560 10a2faf2de8c526feb2ae862519cfd0b 362 Pfam PF03934 Type II secretion system (T2SS), protein K 43 320 1.1E-19 T 22-04-2016 IPR005628 General secretion pathway protein K GO:0009306|GO:0016021 L21SP4_RS03560 10a2faf2de8c526feb2ae862519cfd0b 362 SUPERFAMILY SSF158544 113 208 1.07E-12 T 22-04-2016 L21SP4_RS01690 8dd74a9d04100824fd527dacea0ce013 335 PIRSF PIRSF000148 3 335 2.6E-114 T 22-04-2016 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 L21SP4_RS01690 8dd74a9d04100824fd527dacea0ce013 335 SMART SM00859 5 119 1.9E-20 T 22-04-2016 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 L21SP4_RS01690 8dd74a9d04100824fd527dacea0ce013 335 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 227 241 - T 22-04-2016 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 L21SP4_RS01690 8dd74a9d04100824fd527dacea0ce013 335 PANTHER PTHR10174 83 335 1.1E-63 T 22-04-2016 L21SP4_RS01690 8dd74a9d04100824fd527dacea0ce013 335 PANTHER PTHR10174:SF2 83 335 1.1E-63 T 22-04-2016 L21SP4_RS01690 8dd74a9d04100824fd527dacea0ce013 335 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 137 316 5.9E-49 T 22-04-2016 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 L21SP4_RS01690 8dd74a9d04100824fd527dacea0ce013 335 Gene3D G3DSA:3.30.360.10 141 312 1.2E-74 T 22-04-2016 L21SP4_RS01690 8dd74a9d04100824fd527dacea0ce013 335 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 6 330 2.3E-108 T 22-04-2016 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 L21SP4_RS01690 8dd74a9d04100824fd527dacea0ce013 335 SUPERFAMILY SSF51735 4 155 3.63E-34 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS01690 8dd74a9d04100824fd527dacea0ce013 335 Gene3D G3DSA:3.40.50.720 3 140 4.7E-42 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS01690 8dd74a9d04100824fd527dacea0ce013 335 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 5 117 5.3E-19 T 22-04-2016 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 L21SP4_RS01690 8dd74a9d04100824fd527dacea0ce013 335 SUPERFAMILY SSF55347 127 317 1.93E-67 T 22-04-2016 L21SP4_RS05050 62b36d4ebbf687305a5bdb3114085eda 260 Pfam PF01694 Rhomboid family 45 189 4.3E-36 T 22-04-2016 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 L21SP4_RS05050 62b36d4ebbf687305a5bdb3114085eda 260 SUPERFAMILY SSF144091 6 190 5.62E-42 T 22-04-2016 L21SP4_RS05050 62b36d4ebbf687305a5bdb3114085eda 260 PANTHER PTHR22936 13 203 1.3E-36 T 22-04-2016 IPR002610 Peptidase S54, rhomboid GO:0004252|GO:0006508|GO:0016021 L21SP4_RS05050 62b36d4ebbf687305a5bdb3114085eda 260 Gene3D G3DSA:1.20.1540.10 7 187 2.6E-41 T 22-04-2016 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 L21SP4_RS07295 93ce23ef7d7ea41eb91afb316e5eadd7 238 SUPERFAMILY SSF54523 27 94 4.16E-10 T 22-04-2016 L21SP4_RS07295 93ce23ef7d7ea41eb91afb316e5eadd7 238 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 25 45 - T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site L21SP4_RS07295 93ce23ef7d7ea41eb91afb316e5eadd7 238 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 25 45 5.9E-6 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site L21SP4_RS07295 93ce23ef7d7ea41eb91afb316e5eadd7 238 Pfam PF13544 Type IV pilin N-term methylation site GFxxxE 23 45 2.3E-6 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site L21SP4_RS08465 6c2c3b976a808d2de8c3ee0c6ac662c1 67 Gene3D G3DSA:1.20.5.1030 9 66 1.3E-18 T 22-04-2016 L21SP4_RS08465 6c2c3b976a808d2de8c3ee0c6ac662c1 67 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 14 42 - T 22-04-2016 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 L21SP4_RS08465 6c2c3b976a808d2de8c3ee0c6ac662c1 67 Hamap MF_00422 Protein translocase subunit SecE [secE]. 9 64 11.922 T 22-04-2016 IPR022943 Preprotein translocase subunit SecE L21SP4_RS08465 6c2c3b976a808d2de8c3ee0c6ac662c1 67 PANTHER PTHR33910 1 66 1.3E-13 T 22-04-2016 L21SP4_RS08465 6c2c3b976a808d2de8c3ee0c6ac662c1 67 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 12 66 6.0E-16 T 22-04-2016 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 L21SP4_RS08465 6c2c3b976a808d2de8c3ee0c6ac662c1 67 PANTHER PTHR33910:SF1 1 66 1.3E-13 T 22-04-2016 L21SP4_RS08465 6c2c3b976a808d2de8c3ee0c6ac662c1 67 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 13 64 1.1E-18 T 22-04-2016 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 L21SP4_RS07235 600f266c87db011574549e0bde5af58b 778 Gene3D G3DSA:1.50.10.10 330 694 1.0E-100 T 22-04-2016 IPR012341 Six-hairpin glycosidase GO:0003824 L21SP4_RS07235 600f266c87db011574549e0bde5af58b 778 PIRSF PIRSF036289 6 774 9.9E-171 T 22-04-2016 IPR017045 Maltose phosphorylase/glycosyl hydrolase/vacuolar acid trehalase L21SP4_RS07235 600f266c87db011574549e0bde5af58b 778 PANTHER PTHR11051 38 748 8.8E-126 T 22-04-2016 L21SP4_RS07235 600f266c87db011574549e0bde5af58b 778 Pfam PF03633 Glycosyl hydrolase family 65, C-terminal domain 713 758 1.2E-10 T 22-04-2016 IPR005194 Glycoside hydrolase family 65, C-terminal L21SP4_RS07235 600f266c87db011574549e0bde5af58b 778 Gene3D G3DSA:2.60.420.10 695 758 5.9E-16 T 22-04-2016 L21SP4_RS07235 600f266c87db011574549e0bde5af58b 778 Pfam PF03632 Glycosyl hydrolase family 65 central catalytic domain 334 709 9.0E-92 T 22-04-2016 IPR005195 Glycoside hydrolase, family 65, central catalytic GO:0003824|GO:0005975 L21SP4_RS07235 600f266c87db011574549e0bde5af58b 778 Pfam PF03636 Glycosyl hydrolase family 65, N-terminal domain 21 278 2.1E-47 T 22-04-2016 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 L21SP4_RS07235 600f266c87db011574549e0bde5af58b 778 SUPERFAMILY SSF48208 283 758 5.27E-108 T 22-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP4_RS07235 600f266c87db011574549e0bde5af58b 778 Gene3D G3DSA:2.70.98.40 14 280 8.6E-56 T 22-04-2016 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 L21SP4_RS07235 600f266c87db011574549e0bde5af58b 778 SUPERFAMILY SSF74650 13 279 1.88E-42 T 22-04-2016 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 L21SP4_RS05815 f513eed4367df7b4693b474e365a9d9a 176 Pfam PF06172 Cupin superfamily (DUF985) 11 148 4.1E-38 T 22-04-2016 IPR009327 Cupin domain of unknown function DUF985 L21SP4_RS05815 f513eed4367df7b4693b474e365a9d9a 176 Gene3D G3DSA:2.60.120.10 6 168 2.8E-55 T 22-04-2016 IPR014710 RmlC-like jelly roll fold L21SP4_RS05815 f513eed4367df7b4693b474e365a9d9a 176 SUPERFAMILY SSF51182 5 168 5.49E-53 T 22-04-2016 IPR011051 RmlC-like cupin domain L21SP4_RS05815 f513eed4367df7b4693b474e365a9d9a 176 PANTHER PTHR33387:SF3 1 168 7.7E-51 T 22-04-2016 L21SP4_RS05815 f513eed4367df7b4693b474e365a9d9a 176 PANTHER PTHR33387 1 168 7.7E-51 T 22-04-2016 L21SP4_RS10785 9fceaea61ec720bdcc76906414a8847d 792 Pfam PF08531 Alpha-L-rhamnosidase N-terminal domain 85 224 4.9E-42 T 22-04-2016 IPR013737 Bacterial alpha-L-rhamnosidase N-terminal L21SP4_RS10785 9fceaea61ec720bdcc76906414a8847d 792 PANTHER PTHR33307:SF5 59 780 2.5E-207 T 22-04-2016 L21SP4_RS10785 9fceaea61ec720bdcc76906414a8847d 792 SUPERFAMILY SSF48208 379 761 1.02E-42 T 22-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP4_RS10785 9fceaea61ec720bdcc76906414a8847d 792 PANTHER PTHR33307 59 780 2.5E-207 T 22-04-2016 L21SP4_RS10785 9fceaea61ec720bdcc76906414a8847d 792 PIRSF PIRSF010631 19 789 1.0E-220 T 22-04-2016 IPR016007 Alpha-L-rhamnosidase L21SP4_RS10785 9fceaea61ec720bdcc76906414a8847d 792 Gene3D G3DSA:2.60.120.260 266 356 1.1E-14 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS10785 9fceaea61ec720bdcc76906414a8847d 792 Pfam PF05592 Bacterial alpha-L-rhamnosidase 273 771 3.9E-166 T 22-04-2016 IPR008902 Bacterial alpha-L-rhamnosidase L21SP4_RS02445 66779c48d2990fde28f00349ef058bfc 341 SUPERFAMILY SSF53659 10 334 5.61E-98 T 22-04-2016 L21SP4_RS02445 66779c48d2990fde28f00349ef058bfc 341 PANTHER PTHR30004 7 339 1.5E-128 T 22-04-2016 L21SP4_RS02445 66779c48d2990fde28f00349ef058bfc 341 Hamap MF_00536 4-hydroxythreonine-4-phosphate dehydrogenase [pdxA]. 8 333 32.542 T 22-04-2016 IPR005255 4-hydroxythreonine-4-phosphate dehydrogenase PdxA GO:0008615|GO:0050570|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295|UniPathway: UPA00244 L21SP4_RS02445 66779c48d2990fde28f00349ef058bfc 341 TIGRFAM TIGR00557 pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 11 333 9.6E-106 T 22-04-2016 IPR005255 4-hydroxythreonine-4-phosphate dehydrogenase PdxA GO:0008615|GO:0050570|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295|UniPathway: UPA00244 L21SP4_RS02445 66779c48d2990fde28f00349ef058bfc 341 Gene3D G3DSA:3.40.718.10 9 333 3.5E-115 T 22-04-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 L21SP4_RS02445 66779c48d2990fde28f00349ef058bfc 341 PANTHER PTHR30004:SF6 7 339 1.5E-128 T 22-04-2016 L21SP4_RS02445 66779c48d2990fde28f00349ef058bfc 341 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 39 329 1.7E-98 T 22-04-2016 IPR005255 4-hydroxythreonine-4-phosphate dehydrogenase PdxA GO:0008615|GO:0050570|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295|UniPathway: UPA00244 L21SP4_RS11900 bdaf9d062c4a223f815c335032f7830e 587 Pfam PF01268 Formate--tetrahydrofolate ligase 8 587 2.7E-219 T 22-04-2016 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524|GO:0009396 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00193 L21SP4_RS11900 bdaf9d062c4a223f815c335032f7830e 587 Gene3D G3DSA:3.40.50.300 270 470 6.8E-122 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS11900 bdaf9d062c4a223f815c335032f7830e 587 Gene3D G3DSA:3.40.50.300 21 137 6.8E-122 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS11900 bdaf9d062c4a223f815c335032f7830e 587 SUPERFAMILY SSF52540 10 584 1.99E-196 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS11900 bdaf9d062c4a223f815c335032f7830e 587 Hamap MF_01543 Formate--tetrahydrofolate ligase [fhs]. 7 587 38.83 T 22-04-2016 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524|GO:0009396 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00193 L21SP4_RS11900 bdaf9d062c4a223f815c335032f7830e 587 Gene3D G3DSA:3.30.1510.10 138 268 1.3E-40 T 22-04-2016 L21SP4_RS11900 bdaf9d062c4a223f815c335032f7830e 587 PANTHER PTHR10025 10 586 2.7E-288 T 22-04-2016 L21SP4_RS11900 bdaf9d062c4a223f815c335032f7830e 587 ProSitePatterns PS00722 Formate--tetrahydrofolate ligase signature 2. 350 361 - T 22-04-2016 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0004329|GO:0005524|GO:0009396 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00193 L21SP4_RS11900 bdaf9d062c4a223f815c335032f7830e 587 Gene3D G3DSA:3.10.410.10 472 560 1.5E-27 T 22-04-2016 L21SP4_RS11900 bdaf9d062c4a223f815c335032f7830e 587 ProSitePatterns PS00721 Formate--tetrahydrofolate ligase signature 1. 112 122 - T 22-04-2016 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0004329|GO:0005524|GO:0009396 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00193 L21SP4_RS08635 e0bad8b0e22783615918b81f8ef12dc7 485 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 1 479 34.648 T 22-04-2016 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 UniPathway: UPA00219 L21SP4_RS08635 e0bad8b0e22783615918b81f8ef12dc7 485 Gene3D G3DSA:3.90.190.20 333 473 3.4E-50 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 L21SP4_RS08635 e0bad8b0e22783615918b81f8ef12dc7 485 PANTHER PTHR23135:SF4 9 485 4.8E-185 T 22-04-2016 L21SP4_RS08635 e0bad8b0e22783615918b81f8ef12dc7 485 SUPERFAMILY SSF53244 329 481 1.53E-44 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 L21SP4_RS08635 e0bad8b0e22783615918b81f8ef12dc7 485 Pfam PF02875 Mur ligase family, glutamate ligase domain 329 412 2.1E-17 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 L21SP4_RS08635 e0bad8b0e22783615918b81f8ef12dc7 485 Gene3D G3DSA:3.40.1390.10 16 95 3.4E-24 T 22-04-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 L21SP4_RS08635 e0bad8b0e22783615918b81f8ef12dc7 485 Pfam PF08245 Mur ligase middle domain 107 308 3.6E-51 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 L21SP4_RS08635 e0bad8b0e22783615918b81f8ef12dc7 485 PANTHER PTHR23135 9 485 4.8E-185 T 22-04-2016 L21SP4_RS08635 e0bad8b0e22783615918b81f8ef12dc7 485 SUPERFAMILY SSF63418 1 96 1.96E-22 T 22-04-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 L21SP4_RS08635 e0bad8b0e22783615918b81f8ef12dc7 485 Pfam PF01225 Mur ligase family, catalytic domain 21 93 8.1E-13 T 22-04-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 L21SP4_RS08635 e0bad8b0e22783615918b81f8ef12dc7 485 Gene3D G3DSA:3.40.1190.10 98 332 1.7E-82 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 L21SP4_RS08635 e0bad8b0e22783615918b81f8ef12dc7 485 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 19 479 3.0E-160 T 22-04-2016 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 UniPathway: UPA00219 L21SP4_RS08635 e0bad8b0e22783615918b81f8ef12dc7 485 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 105 129 - T 22-04-2016 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 L21SP4_RS08635 e0bad8b0e22783615918b81f8ef12dc7 485 SUPERFAMILY SSF53623 98 328 5.1E-74 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 L21SP4_RS05745 d7578f6f01e90beece8c25fe7637fda4 262 TIGRFAM TIGR03008 pepcterm_CAAX: CAAX prenyl protease-related protein 55 262 1.7E-32 T 22-04-2016 IPR014346 Prenyl protease-related L21SP4_RS05745 d7578f6f01e90beece8c25fe7637fda4 262 Pfam PF02517 CAAX protease self-immunity 156 248 1.1E-10 T 22-04-2016 IPR003675 CAAX amino terminal protease GO:0016020 L21SP4_RS05635 5183a7347dc8793078c7eed155c9cfd5 294 Gene3D G3DSA:3.40.50.620 5 179 5.8E-75 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP4_RS05635 5183a7347dc8793078c7eed155c9cfd5 294 Gene3D G3DSA:3.30.1300.10 181 289 9.2E-30 T 22-04-2016 L21SP4_RS05635 5183a7347dc8793078c7eed155c9cfd5 294 Hamap MF_00158 Pantothenate synthetase [panC]. 8 285 38.642 T 22-04-2016 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1|UniPathway: UPA00028 L21SP4_RS05635 5183a7347dc8793078c7eed155c9cfd5 294 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 16 282 4.2E-93 T 22-04-2016 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1|UniPathway: UPA00028 L21SP4_RS05635 5183a7347dc8793078c7eed155c9cfd5 294 Pfam PF02569 Pantoate-beta-alanine ligase 9 282 8.6E-98 T 22-04-2016 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1|UniPathway: UPA00028 L21SP4_RS05635 5183a7347dc8793078c7eed155c9cfd5 294 PANTHER PTHR21299:SF1 1 291 2.0E-128 T 22-04-2016 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1|UniPathway: UPA00028 L21SP4_RS05635 5183a7347dc8793078c7eed155c9cfd5 294 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 33 92 1.1E-8 T 22-04-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 L21SP4_RS05635 5183a7347dc8793078c7eed155c9cfd5 294 PANTHER PTHR21299 1 291 2.0E-128 T 22-04-2016 L21SP4_RS05635 5183a7347dc8793078c7eed155c9cfd5 294 SUPERFAMILY SSF52374 6 286 4.02E-103 T 22-04-2016 L21SP4_RS04565 cb67b3312e2cd9051db2b981af2d1dd3 687 Gene3D G3DSA:1.50.10.10 101 271 2.4E-4 T 22-04-2016 IPR012341 Six-hairpin glycosidase GO:0003824 L21SP4_RS04565 cb67b3312e2cd9051db2b981af2d1dd3 687 SUPERFAMILY SSF48208 230 402 1.47E-20 T 22-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP4_RS04565 cb67b3312e2cd9051db2b981af2d1dd3 687 SUPERFAMILY SSF48208 96 201 1.47E-20 T 22-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP4_RS04565 cb67b3312e2cd9051db2b981af2d1dd3 687 PANTHER PTHR31151 247 581 1.7E-19 T 22-04-2016 L21SP4_RS04565 cb67b3312e2cd9051db2b981af2d1dd3 687 PANTHER PTHR31151 97 219 1.7E-19 T 22-04-2016 L21SP4_RS04565 cb67b3312e2cd9051db2b981af2d1dd3 687 Pfam PF07944 Beta-L-arabinofuranosidase, GH127 62 190 9.7E-10 T 22-04-2016 IPR012878 Beta-L-arabinofuranosidase, GH127 KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18 L21SP4_RS04565 cb67b3312e2cd9051db2b981af2d1dd3 687 Pfam PF07944 Beta-L-arabinofuranosidase, GH127 234 581 5.5E-33 T 22-04-2016 IPR012878 Beta-L-arabinofuranosidase, GH127 KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18 L21SP4_RS08540 fba8aae30252c161d696b11b0a8a5e25 180 Gene3D G3DSA:3.40.220.10 3 173 5.5E-70 T 22-04-2016 L21SP4_RS08540 fba8aae30252c161d696b11b0a8a5e25 180 SUPERFAMILY SSF52949 4 173 4.04E-64 T 22-04-2016 L21SP4_RS08540 fba8aae30252c161d696b11b0a8a5e25 180 PANTHER PTHR11106 4 168 2.2E-82 T 22-04-2016 L21SP4_RS08540 fba8aae30252c161d696b11b0a8a5e25 180 Pfam PF01661 Macro domain 21 132 4.6E-43 T 22-04-2016 IPR002589 Macro domain L21SP4_RS08540 fba8aae30252c161d696b11b0a8a5e25 180 SMART SM00506 4 133 1.2E-43 T 22-04-2016 IPR002589 Macro domain L21SP4_RS03030 a5d750e4378f4a87b8db04ebc1098171 203 PANTHER PTHR12993 1 192 6.3E-28 T 22-04-2016 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related L21SP4_RS03030 a5d750e4378f4a87b8db04ebc1098171 203 Pfam PF02585 GlcNAc-PI de-N-acetylase 4 117 2.7E-24 T 22-04-2016 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related L21SP4_RS03030 a5d750e4378f4a87b8db04ebc1098171 203 Gene3D G3DSA:3.40.50.10320 2 198 8.9E-50 T 22-04-2016 IPR024078 Putative deacetylase LmbE-like domain L21SP4_RS03030 a5d750e4378f4a87b8db04ebc1098171 203 SUPERFAMILY SSF102588 1 195 3.53E-47 T 22-04-2016 IPR024078 Putative deacetylase LmbE-like domain L21SP4_RS01455 c3a0aada51ee1f3270262eb837dc22a7 322 Gene3D G3DSA:3.30.420.40 3 145 2.4E-38 T 22-04-2016 L21SP4_RS01455 c3a0aada51ee1f3270262eb837dc22a7 322 SUPERFAMILY SSF53067 7 320 8.22E-60 T 22-04-2016 L21SP4_RS01455 c3a0aada51ee1f3270262eb837dc22a7 322 PANTHER PTHR18964 8 202 3.4E-70 T 22-04-2016 L21SP4_RS01455 c3a0aada51ee1f3270262eb837dc22a7 322 PANTHER PTHR18964 220 320 3.4E-70 T 22-04-2016 L21SP4_RS01455 c3a0aada51ee1f3270262eb837dc22a7 322 PANTHER PTHR18964:SF110 8 202 3.4E-70 T 22-04-2016 L21SP4_RS01455 c3a0aada51ee1f3270262eb837dc22a7 322 PANTHER PTHR18964:SF110 220 320 3.4E-70 T 22-04-2016 L21SP4_RS01455 c3a0aada51ee1f3270262eb837dc22a7 322 Gene3D G3DSA:3.30.420.40 146 303 1.0E-41 T 22-04-2016 L21SP4_RS01455 c3a0aada51ee1f3270262eb837dc22a7 322 Pfam PF00480 ROK family 8 319 1.8E-53 T 22-04-2016 IPR000600 ROK family L21SP4_RS10080 5fc181a1cd13798d30b1519ea74fd14b 265 Gene3D G3DSA:2.40.30.10 3 96 1.7E-21 T 22-04-2016 L21SP4_RS10080 5fc181a1cd13798d30b1519ea74fd14b 265 PANTHER PTHR19370 19 249 3.5E-37 T 22-04-2016 L21SP4_RS10080 5fc181a1cd13798d30b1519ea74fd14b 265 Gene3D G3DSA:3.40.50.80 103 214 3.0E-26 T 22-04-2016 L21SP4_RS10080 5fc181a1cd13798d30b1519ea74fd14b 265 PANTHER PTHR19370:SF68 19 249 3.5E-37 T 22-04-2016 L21SP4_RS10080 5fc181a1cd13798d30b1519ea74fd14b 265 Gene3D G3DSA:2.10.240.10 217 261 1.2E-13 T 22-04-2016 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain UniPathway: UPA00070 L21SP4_RS10080 5fc181a1cd13798d30b1519ea74fd14b 265 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 217 259 1.5E-12 T 22-04-2016 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain UniPathway: UPA00070 L21SP4_RS10080 5fc181a1cd13798d30b1519ea74fd14b 265 SUPERFAMILY SSF63380 16 98 1.97E-17 T 22-04-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 L21SP4_RS10080 5fc181a1cd13798d30b1519ea74fd14b 265 PIRSF PIRSF006816 5 264 1.5E-54 T 22-04-2016 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 UniPathway: UPA00070 L21SP4_RS10080 5fc181a1cd13798d30b1519ea74fd14b 265 SUPERFAMILY SSF52343 93 259 1.1E-27 T 22-04-2016 L21SP4_RS10080 5fc181a1cd13798d30b1519ea74fd14b 265 Pfam PF00175 Oxidoreductase NAD-binding domain 131 201 4.1E-5 T 22-04-2016 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 L21SP4_RS05040 d25bb71102616d15dfaacc9c038f39ba 334 SUPERFAMILY SSF141523 206 332 2.35E-26 T 22-04-2016 L21SP4_RS05040 d25bb71102616d15dfaacc9c038f39ba 334 SMART SM00257 160 203 1.7E-8 T 22-04-2016 IPR018392 LysM domain L21SP4_RS05040 d25bb71102616d15dfaacc9c038f39ba 334 Pfam PF03734 L,D-transpeptidase catalytic domain 208 332 1.6E-19 T 22-04-2016 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 UniPathway: UPA00219 L21SP4_RS05040 d25bb71102616d15dfaacc9c038f39ba 334 Pfam PF01476 LysM domain 161 201 1.9E-9 T 22-04-2016 IPR018392 LysM domain L21SP4_RS05040 d25bb71102616d15dfaacc9c038f39ba 334 Gene3D G3DSA:2.40.440.10 208 333 9.6E-29 T 22-04-2016 L21SP4_RS05040 d25bb71102616d15dfaacc9c038f39ba 334 Gene3D G3DSA:3.10.350.10 160 201 2.5E-12 T 22-04-2016 IPR018392 LysM domain L21SP4_RS05040 d25bb71102616d15dfaacc9c038f39ba 334 SUPERFAMILY SSF54106 160 201 9.29E-9 T 22-04-2016 IPR018392 LysM domain L21SP4_RS05040 d25bb71102616d15dfaacc9c038f39ba 334 PANTHER PTHR30582:SF1 208 334 2.2E-26 T 22-04-2016 L21SP4_RS05040 d25bb71102616d15dfaacc9c038f39ba 334 PANTHER PTHR30582 208 334 2.2E-26 T 22-04-2016 L21SP4_RS11185 596e7ce243b6f5567f06bfe38e607fff 178 Pfam PF05523 WxcM-like, C-terminal 32 84 4.0E-11 T 22-04-2016 IPR008894 WxcM-like, C-terminal MetaCyc: PWY-6953|MetaCyc: PWY-7688 L21SP4_RS11185 596e7ce243b6f5567f06bfe38e607fff 178 Pfam PF05523 WxcM-like, C-terminal 106 159 6.7E-10 T 22-04-2016 IPR008894 WxcM-like, C-terminal MetaCyc: PWY-6953|MetaCyc: PWY-7688 L21SP4_RS11185 596e7ce243b6f5567f06bfe38e607fff 178 SUPERFAMILY SSF51182 33 159 4.46E-17 T 22-04-2016 IPR011051 RmlC-like cupin domain L21SP4_RS10445 cd2acf0df475f107be67c06b6fdf1d44 581 Gene3D G3DSA:3.90.400.10 144 211 3.4E-22 T 22-04-2016 L21SP4_RS10445 cd2acf0df475f107be67c06b6fdf1d44 581 PANTHER PTHR10357 397 540 1.1E-120 T 22-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 L21SP4_RS10445 cd2acf0df475f107be67c06b6fdf1d44 581 PANTHER PTHR10357 76 348 1.1E-120 T 22-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 L21SP4_RS10445 cd2acf0df475f107be67c06b6fdf1d44 581 PANTHER PTHR10357:SF132 397 540 1.1E-120 T 22-04-2016 L21SP4_RS10445 cd2acf0df475f107be67c06b6fdf1d44 581 PANTHER PTHR10357:SF132 76 348 1.1E-120 T 22-04-2016 L21SP4_RS10445 cd2acf0df475f107be67c06b6fdf1d44 581 PIRSF PIRSF003059 10 580 3.9E-176 T 22-04-2016 IPR016377 Sucrose phosphorylase GO:0005985|GO:0009018 KEGG: 00500+2.4.1.7|MetaCyc: PWY-5384 L21SP4_RS10445 cd2acf0df475f107be67c06b6fdf1d44 581 Gene3D G3DSA:2.60.40.1180 508 579 3.8E-8 T 22-04-2016 IPR013780 Glycosyl hydrolase, all-beta L21SP4_RS10445 cd2acf0df475f107be67c06b6fdf1d44 581 Pfam PF00128 Alpha amylase, catalytic domain 91 284 5.7E-16 T 22-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 L21SP4_RS10445 cd2acf0df475f107be67c06b6fdf1d44 581 Gene3D G3DSA:3.20.20.80 218 490 7.2E-95 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP4_RS10445 cd2acf0df475f107be67c06b6fdf1d44 581 Gene3D G3DSA:3.20.20.80 57 143 7.2E-95 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP4_RS10445 cd2acf0df475f107be67c06b6fdf1d44 581 SUPERFAMILY SSF51445 406 540 4.13E-83 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily L21SP4_RS10445 cd2acf0df475f107be67c06b6fdf1d44 581 SUPERFAMILY SSF51445 54 365 4.13E-83 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily L21SP4_RS10445 cd2acf0df475f107be67c06b6fdf1d44 581 SMART SM00642 71 489 2.7E-5 T 22-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 L21SP4_RS08085 64362175ac79dede6f80fc7dd685ca1b 87 SMART SM01387 6 86 1.6E-40 T 22-04-2016 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS08085 64362175ac79dede6f80fc7dd685ca1b 87 Pfam PF00312 Ribosomal protein S15 6 86 9.9E-32 T 22-04-2016 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS08085 64362175ac79dede6f80fc7dd685ca1b 87 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 3 87 5.2E-34 T 22-04-2016 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 L21SP4_RS08085 64362175ac79dede6f80fc7dd685ca1b 87 ProSitePatterns PS00362 Ribosomal protein S15 signature. 37 67 - T 22-04-2016 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS08085 64362175ac79dede6f80fc7dd685ca1b 87 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 11 86 6.0E-22 T 22-04-2016 L21SP4_RS08085 64362175ac79dede6f80fc7dd685ca1b 87 PANTHER PTHR23321 1 87 6.8E-34 T 22-04-2016 L21SP4_RS08085 64362175ac79dede6f80fc7dd685ca1b 87 Gene3D G3DSA:1.10.287.10 3 87 4.6E-33 T 22-04-2016 IPR009068 S15/NS1, RNA-binding Reactome: REACT_71 L21SP4_RS08085 64362175ac79dede6f80fc7dd685ca1b 87 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 1 87 21.225 T 22-04-2016 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 L21SP4_RS08085 64362175ac79dede6f80fc7dd685ca1b 87 SUPERFAMILY SSF47060 3 87 2.94E-31 T 22-04-2016 IPR009068 S15/NS1, RNA-binding Reactome: REACT_71 L21SP4_RS09335 1860c5a34f9971cd8c6293aa73f849a1 308 SUPERFAMILY SSF56784 107 267 2.87E-13 T 22-04-2016 IPR023214 HAD-like domain L21SP4_RS09335 1860c5a34f9971cd8c6293aa73f849a1 308 Gene3D G3DSA:3.40.50.1000 157 270 1.6E-7 T 22-04-2016 IPR023214 HAD-like domain L21SP4_RS01935 03b673be645df19e2f9d006662c752d9 452 SUPERFAMILY SSF53743 11 309 3.92E-28 T 22-04-2016 IPR009015 L-fucose isomerase, N-terminal/central domain GO:0005737|GO:0005996|GO:0016861 L21SP4_RS01935 03b673be645df19e2f9d006662c752d9 452 PANTHER PTHR36120 19 439 5.6E-68 T 22-04-2016 L21SP4_RS01935 03b673be645df19e2f9d006662c752d9 452 PANTHER PTHR36120:SF1 19 439 5.6E-68 T 22-04-2016 L21SP4_RS01935 03b673be645df19e2f9d006662c752d9 452 Pfam PF02952 L-fucose isomerase, C-terminal domain 357 439 8.9E-10 T 22-04-2016 IPR015888 L-fucose isomerase, C-terminal GO:0005737|GO:0006004|GO:0008736 KEGG: 00051+5.3.1.25|UniPathway: UPA00563 L21SP4_RS06195 1e09c7a514a57d6c1d251a1d6106a5c2 259 PANTHER PTHR36303 2 257 2.5E-122 T 22-04-2016 L21SP4_RS06195 1e09c7a514a57d6c1d251a1d6106a5c2 259 SUPERFAMILY SSF56300 2 255 2.71E-78 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like L21SP4_RS06195 1e09c7a514a57d6c1d251a1d6106a5c2 259 Gene3D G3DSA:3.60.21.30 2 256 3.6E-102 T 22-04-2016 L21SP4_RS06195 1e09c7a514a57d6c1d251a1d6106a5c2 259 PIRSF PIRSF004789 1 259 3.2E-87 T 22-04-2016 IPR005235 Metallophosphoesterase, YmdB-like L21SP4_RS06195 1e09c7a514a57d6c1d251a1d6106a5c2 259 PANTHER PTHR36303:SF1 2 257 2.5E-122 T 22-04-2016 L21SP4_RS06195 1e09c7a514a57d6c1d251a1d6106a5c2 259 Pfam PF13277 YmdB-like protein 4 254 6.5E-99 T 22-04-2016 IPR005235 Metallophosphoesterase, YmdB-like L21SP4_RS01310 3bc3c5f2ac39ab94cb9bd92707f84b60 413 Gene3D G3DSA:1.10.287.130 317 393 5.3E-15 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS01310 3bc3c5f2ac39ab94cb9bd92707f84b60 413 Pfam PF00512 His Kinase A (phospho-acceptor) domain 327 393 4.6E-14 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS01310 3bc3c5f2ac39ab94cb9bd92707f84b60 413 SUPERFAMILY SSF55785 190 271 1.09E-8 T 22-04-2016 IPR000014 PAS domain L21SP4_RS01310 3bc3c5f2ac39ab94cb9bd92707f84b60 413 Gene3D G3DSA:3.30.450.20 192 253 7.0E-8 T 22-04-2016 L21SP4_RS01310 3bc3c5f2ac39ab94cb9bd92707f84b60 413 Pfam PF13188 PAS domain 199 242 9.3E-6 T 22-04-2016 IPR000014 PAS domain L21SP4_RS01310 3bc3c5f2ac39ab94cb9bd92707f84b60 413 SUPERFAMILY SSF47384 313 397 7.06E-13 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS01310 3bc3c5f2ac39ab94cb9bd92707f84b60 413 SMART SM00388 324 398 1.0E-10 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS01310 3bc3c5f2ac39ab94cb9bd92707f84b60 413 SMART SM00091 196 262 0.0016 T 22-04-2016 IPR000014 PAS domain L21SP4_RS01310 3bc3c5f2ac39ab94cb9bd92707f84b60 413 PANTHER PTHR24423 194 393 6.2E-21 T 22-04-2016 L21SP4_RS01310 3bc3c5f2ac39ab94cb9bd92707f84b60 413 PANTHER PTHR24423 1 8 6.2E-21 T 22-04-2016 L21SP4_RS04520 56e40baf3067754a48d5c666fe60b9a2 144 Pfam PF01850 PIN domain 3 134 6.4E-12 T 22-04-2016 IPR002716 PIN domain L21SP4_RS04520 56e40baf3067754a48d5c666fe60b9a2 144 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 141 11.393 T 22-04-2016 IPR022907 VapC family GO:0004540 L21SP4_RS04520 56e40baf3067754a48d5c666fe60b9a2 144 Gene3D G3DSA:3.40.50.1010 3 134 2.6E-6 T 22-04-2016 IPR029060 PIN domain-like L21SP4_RS04520 56e40baf3067754a48d5c666fe60b9a2 144 SUPERFAMILY SSF88723 3 135 9.53E-19 T 22-04-2016 IPR029060 PIN domain-like L21SP4_RS04520 56e40baf3067754a48d5c666fe60b9a2 144 TIGRFAM TIGR00028 Mtu_PIN_fam: toxin-antitoxin system PIN domain toxin 2 142 1.5E-26 T 22-04-2016 IPR006226 PIN domain toxin GO:0016788 L21SP4_RS08145 7f5f219fe7d626012dc27d35dd881b96 157 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 58 76 - T 22-04-2016 IPR030489 Transcription regulator Rrf2-type, conserved site L21SP4_RS08145 7f5f219fe7d626012dc27d35dd881b96 157 SUPERFAMILY SSF46785 13 142 1.01E-26 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS08145 7f5f219fe7d626012dc27d35dd881b96 157 Gene3D G3DSA:1.10.10.10 12 148 3.1E-26 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS08145 7f5f219fe7d626012dc27d35dd881b96 157 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 12 140 1.9E-25 T 22-04-2016 IPR000944 Transcription regulator Rrf2-type L21SP4_RS08145 7f5f219fe7d626012dc27d35dd881b96 157 PANTHER PTHR33221 12 143 5.3E-27 T 22-04-2016 L21SP4_RS08145 7f5f219fe7d626012dc27d35dd881b96 157 Pfam PF02082 Transcriptional regulator 12 91 2.4E-19 T 22-04-2016 IPR000944 Transcription regulator Rrf2-type L21SP4_RS09695 12fb395cd9b7f83a25dd1865e34197b1 204 PANTHER PTHR34580:SF3 1 122 2.4E-19 T 22-04-2016 L21SP4_RS09695 12fb395cd9b7f83a25dd1865e34197b1 204 PANTHER PTHR34580 1 122 2.4E-19 T 22-04-2016 L21SP4_RS09695 12fb395cd9b7f83a25dd1865e34197b1 204 Gene3D G3DSA:1.10.10.10 30 72 1.4E-5 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS09695 12fb395cd9b7f83a25dd1865e34197b1 204 SUPERFAMILY SSF46785 11 56 7.82E-5 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS10695 843566c8a4d2543f900d82a52b3959af 185 Hamap MF_00528 Septum formation protein Maf [maf]. 9 184 29.484 T 22-04-2016 IPR003697 Maf-like protein GO:0005737 L21SP4_RS10695 843566c8a4d2543f900d82a52b3959af 185 PIRSF PIRSF006305 1 185 1.4E-56 T 22-04-2016 IPR003697 Maf-like protein GO:0005737 L21SP4_RS10695 843566c8a4d2543f900d82a52b3959af 185 TIGRFAM TIGR00172 maf: septum formation protein Maf 9 184 1.6E-51 T 22-04-2016 IPR003697 Maf-like protein GO:0005737 L21SP4_RS10695 843566c8a4d2543f900d82a52b3959af 185 Pfam PF02545 Maf-like protein 10 183 9.2E-58 T 22-04-2016 IPR003697 Maf-like protein GO:0005737 L21SP4_RS10695 843566c8a4d2543f900d82a52b3959af 185 PANTHER PTHR11746 126 182 1.1E-12 T 22-04-2016 L21SP4_RS10695 843566c8a4d2543f900d82a52b3959af 185 SUPERFAMILY SSF52972 8 183 1.83E-59 T 22-04-2016 IPR029001 Inosine triphosphate pyrophosphatase-like L21SP4_RS10695 843566c8a4d2543f900d82a52b3959af 185 Gene3D G3DSA:3.90.950.10 9 183 9.3E-66 T 22-04-2016 IPR029001 Inosine triphosphate pyrophosphatase-like L21SP4_RS08580 219135d0a44616742c3d514e2424b530 99 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 10 53 1.2E-19 T 22-04-2016 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 L21SP4_RS08580 219135d0a44616742c3d514e2424b530 99 PANTHER PTHR33162 1 72 1.5E-15 T 22-04-2016 L21SP4_RS08580 219135d0a44616742c3d514e2424b530 99 Pfam PF02416 mttA/Hcf106 family 12 56 1.5E-18 T 22-04-2016 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 L21SP4_RS08580 219135d0a44616742c3d514e2424b530 99 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 8 96 18.506 T 22-04-2016 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 L21SP4_RS05550 a8684946e802d39fae5638b1cc6f850c 259 Pfam PF02424 ApbE family 1 237 1.3E-22 T 22-04-2016 IPR024932 Flavin transferase ApbE GO:0017013 L21SP4_RS05550 a8684946e802d39fae5638b1cc6f850c 259 SUPERFAMILY SSF143631 1 243 1.86E-32 T 22-04-2016 IPR003374 ApbE-like domain L21SP4_RS05550 a8684946e802d39fae5638b1cc6f850c 259 PANTHER PTHR30040 1 236 1.5E-20 T 22-04-2016 L21SP4_RS06210 28c0fbf427ff7e552c2597d206e79bbc 840 TIGRFAM TIGR02093 P_ylase: glycogen/starch/alpha-glucan phosphorylases 28 827 0.0 T 22-04-2016 IPR011833 Glycogen/starch/alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: REACT_474 L21SP4_RS06210 28c0fbf427ff7e552c2597d206e79bbc 840 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 671 683 - T 22-04-2016 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: REACT_474 L21SP4_RS06210 28c0fbf427ff7e552c2597d206e79bbc 840 Gene3D G3DSA:3.40.50.2000 497 812 1.3E-135 T 22-04-2016 L21SP4_RS06210 28c0fbf427ff7e552c2597d206e79bbc 840 PANTHER PTHR11468 39 833 0.0 T 22-04-2016 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: REACT_474 L21SP4_RS06210 28c0fbf427ff7e552c2597d206e79bbc 840 Pfam PF00343 Carbohydrate phosphorylase 115 827 0.0 T 22-04-2016 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: REACT_474 L21SP4_RS06210 28c0fbf427ff7e552c2597d206e79bbc 840 PIRSF PIRSF000460 11 839 5.6E-229 T 22-04-2016 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: REACT_474 L21SP4_RS06210 28c0fbf427ff7e552c2597d206e79bbc 840 Gene3D G3DSA:3.40.50.2000 21 496 6.6E-195 T 22-04-2016 L21SP4_RS06210 28c0fbf427ff7e552c2597d206e79bbc 840 SUPERFAMILY SSF53756 21 832 0.0 T 22-04-2016 L21SP4_RS10030 1e6b9ada28c76b090d1aeb6b8340ceb9 267 TIGRFAM TIGR00245 TIGR00245: TIGR00245 family protein 9 257 1.5E-60 T 22-04-2016 IPR005226 UPF0014 family L21SP4_RS10030 1e6b9ada28c76b090d1aeb6b8340ceb9 267 PANTHER PTHR30028 1 266 8.4E-77 T 22-04-2016 L21SP4_RS10030 1e6b9ada28c76b090d1aeb6b8340ceb9 267 Pfam PF03649 Uncharacterised protein family (UPF0014) 9 251 5.9E-84 T 22-04-2016 IPR005226 UPF0014 family L21SP4_RS10030 1e6b9ada28c76b090d1aeb6b8340ceb9 267 PANTHER PTHR30028:SF0 1 266 8.4E-77 T 22-04-2016 IPR005226 UPF0014 family L21SP4_RS00045 0af260c6fb062f41ffefcb1e0e9b7102 121 SUPERFAMILY SSF81301 2 109 5.89E-9 T 22-04-2016 L21SP4_RS04830 cf9f78e0be4df86182a5a75edf403050 571 Gene3D G3DSA:3.30.1360.70 2 106 2.4E-27 T 22-04-2016 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 L21SP4_RS04830 cf9f78e0be4df86182a5a75edf403050 571 PANTHER PTHR11956 2 571 3.5E-214 T 22-04-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 L21SP4_RS04830 cf9f78e0be4df86182a5a75edf403050 571 Gene3D G3DSA:1.10.730.10 447 571 1.6E-33 T 22-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 L21SP4_RS04830 cf9f78e0be4df86182a5a75edf403050 571 Pfam PF00750 tRNA synthetases class I (R) 113 439 7.0E-95 T 22-04-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 L21SP4_RS04830 cf9f78e0be4df86182a5a75edf403050 571 Hamap MF_00123 Arginine--tRNA ligase [argS]. 4 571 25.919 T 22-04-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 L21SP4_RS04830 cf9f78e0be4df86182a5a75edf403050 571 PRINTS PR01038 Arginyl-tRNA synthetase signature 132 148 1.4E-24 T 22-04-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 L21SP4_RS04830 cf9f78e0be4df86182a5a75edf403050 571 PRINTS PR01038 Arginyl-tRNA synthetase signature 300 321 1.4E-24 T 22-04-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 L21SP4_RS04830 cf9f78e0be4df86182a5a75edf403050 571 PRINTS PR01038 Arginyl-tRNA synthetase signature 156 169 1.4E-24 T 22-04-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 L21SP4_RS04830 cf9f78e0be4df86182a5a75edf403050 571 PRINTS PR01038 Arginyl-tRNA synthetase signature 117 132 1.4E-24 T 22-04-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 L21SP4_RS04830 cf9f78e0be4df86182a5a75edf403050 571 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 12 89 4.3E-19 T 22-04-2016 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 L21SP4_RS04830 cf9f78e0be4df86182a5a75edf403050 571 SMART SM00836 453 571 3.7E-37 T 22-04-2016 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 L21SP4_RS04830 cf9f78e0be4df86182a5a75edf403050 571 Gene3D G3DSA:3.40.50.620 111 445 1.1E-110 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP4_RS04830 cf9f78e0be4df86182a5a75edf403050 571 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 27 571 8.3E-151 T 22-04-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 L21SP4_RS04830 cf9f78e0be4df86182a5a75edf403050 571 Pfam PF05746 DALR anticodon binding domain 453 571 2.9E-30 T 22-04-2016 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 L21SP4_RS04830 cf9f78e0be4df86182a5a75edf403050 571 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 125 136 - T 22-04-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 L21SP4_RS04830 cf9f78e0be4df86182a5a75edf403050 571 SUPERFAMILY SSF55190 6 100 1.57E-18 T 22-04-2016 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 L21SP4_RS04830 cf9f78e0be4df86182a5a75edf403050 571 SUPERFAMILY SSF47323 448 571 6.54E-33 T 22-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 L21SP4_RS04830 cf9f78e0be4df86182a5a75edf403050 571 SMART SM01016 4 89 2.8E-22 T 22-04-2016 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 L21SP4_RS04830 cf9f78e0be4df86182a5a75edf403050 571 SUPERFAMILY SSF52374 111 447 4.38E-88 T 22-04-2016 L21SP4_RS01080 00f649d8ff800d39bd826ce10dd01d42 223 Pfam PF06439 Domain of Unknown Function (DUF1080) 28 208 3.6E-40 T 22-04-2016 IPR010496 Domain of unknown function DUF1080 L21SP4_RS09010 e830c0e61789cdeaa19d7d394b174be2 295 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 292 39.153 T 22-04-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 L21SP4_RS09010 e830c0e61789cdeaa19d7d394b174be2 295 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 5 120 2.4E-35 T 22-04-2016 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 L21SP4_RS09010 e830c0e61789cdeaa19d7d394b174be2 295 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 269 277 - T 22-04-2016 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 L21SP4_RS09010 e830c0e61789cdeaa19d7d394b174be2 295 Gene3D G3DSA:3.40.50.720 140 273 3.7E-56 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS09010 e830c0e61789cdeaa19d7d394b174be2 295 SUPERFAMILY SSF53223 1 121 2.59E-35 T 22-04-2016 L21SP4_RS09010 e830c0e61789cdeaa19d7d394b174be2 295 PANTHER PTHR10025 1 291 4.5E-157 T 22-04-2016 L21SP4_RS09010 e830c0e61789cdeaa19d7d394b174be2 295 SUPERFAMILY SSF51735 122 290 7.73E-50 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS09010 e830c0e61789cdeaa19d7d394b174be2 295 Gene3D G3DSA:3.40.192.10 7 139 1.9E-45 T 22-04-2016 L21SP4_RS09010 e830c0e61789cdeaa19d7d394b174be2 295 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 123 290 1.6E-68 T 22-04-2016 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 L21SP4_RS09010 e830c0e61789cdeaa19d7d394b174be2 295 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 33 55 1.4E-80 T 22-04-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 L21SP4_RS09010 e830c0e61789cdeaa19d7d394b174be2 295 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 74 101 1.4E-80 T 22-04-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 L21SP4_RS09010 e830c0e61789cdeaa19d7d394b174be2 295 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 265 283 1.4E-80 T 22-04-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 L21SP4_RS09010 e830c0e61789cdeaa19d7d394b174be2 295 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 154 174 1.4E-80 T 22-04-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 L21SP4_RS09010 e830c0e61789cdeaa19d7d394b174be2 295 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 207 236 1.4E-80 T 22-04-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 L21SP4_RS09010 e830c0e61789cdeaa19d7d394b174be2 295 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 248 264 1.4E-80 T 22-04-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 L21SP4_RS09010 e830c0e61789cdeaa19d7d394b174be2 295 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 109 130 1.4E-80 T 22-04-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 L21SP4_RS03610 092856bbac1e5fcc1c4965eb0cb26ba0 331 PANTHER PTHR33371:SF4 4 281 6.9E-24 T 22-04-2016 L21SP4_RS03610 092856bbac1e5fcc1c4965eb0cb26ba0 331 Pfam PF02470 MlaD protein 42 116 1.4E-15 T 22-04-2016 IPR003399 Mce/MlaD L21SP4_RS03610 092856bbac1e5fcc1c4965eb0cb26ba0 331 PANTHER PTHR33371 4 281 6.9E-24 T 22-04-2016 L21SP4_RS05295 c579d974869a77dcf756e050ef01f3c0 894 PANTHER PTHR10342 633 701 1.6E-75 T 22-04-2016 L21SP4_RS05295 c579d974869a77dcf756e050ef01f3c0 894 PANTHER PTHR10342 214 612 1.6E-75 T 22-04-2016 L21SP4_RS05295 c579d974869a77dcf756e050ef01f3c0 894 Pfam PF13646 HEAT repeats 725 787 1.0E-6 T 22-04-2016 L21SP4_RS05295 c579d974869a77dcf756e050ef01f3c0 894 SUPERFAMILY SSF48371 726 851 5.76E-9 T 22-04-2016 IPR016024 Armadillo-type fold GO:0005488 L21SP4_RS05295 c579d974869a77dcf756e050ef01f3c0 894 SUPERFAMILY SSF53649 637 682 9.49E-85 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS05295 c579d974869a77dcf756e050ef01f3c0 894 SUPERFAMILY SSF53649 245 597 9.49E-85 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS05295 c579d974869a77dcf756e050ef01f3c0 894 Gene3D G3DSA:3.40.720.10 247 556 1.8E-57 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS05295 c579d974869a77dcf756e050ef01f3c0 894 Gene3D G3DSA:1.25.10.10 730 839 6.8E-8 T 22-04-2016 IPR011989 Armadillo-like helical L21SP4_RS05295 c579d974869a77dcf756e050ef01f3c0 894 ProSitePatterns PS00523 Sulfatases signature 1. 292 304 - T 22-04-2016 IPR024607 Sulfatase, conserved site L21SP4_RS05295 c579d974869a77dcf756e050ef01f3c0 894 PANTHER PTHR10342:SF199 633 701 1.6E-75 T 22-04-2016 L21SP4_RS05295 c579d974869a77dcf756e050ef01f3c0 894 PANTHER PTHR10342:SF199 214 612 1.6E-75 T 22-04-2016 L21SP4_RS05295 c579d974869a77dcf756e050ef01f3c0 894 Gene3D G3DSA:3.30.1120.10 576 599 7.4E-15 T 22-04-2016 L21SP4_RS05295 c579d974869a77dcf756e050ef01f3c0 894 Gene3D G3DSA:3.30.1120.10 639 683 7.4E-15 T 22-04-2016 L21SP4_RS05295 c579d974869a77dcf756e050ef01f3c0 894 Pfam PF00884 Sulfatase 247 543 1.4E-42 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS08055 63a38a48891934d18019be642f616c78 228 Pfam PF01476 LysM domain 176 224 1.4E-7 T 22-04-2016 IPR018392 LysM domain L21SP4_RS08055 63a38a48891934d18019be642f616c78 228 Gene3D G3DSA:1.25.40.10 22 86 1.0E-9 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS08055 63a38a48891934d18019be642f616c78 228 Gene3D G3DSA:3.10.350.10 174 224 3.7E-8 T 22-04-2016 IPR018392 LysM domain L21SP4_RS08055 63a38a48891934d18019be642f616c78 228 SMART SM00257 175 224 2.2E-7 T 22-04-2016 IPR018392 LysM domain L21SP4_RS08055 63a38a48891934d18019be642f616c78 228 SUPERFAMILY SSF54106 174 225 2.62E-5 T 22-04-2016 IPR018392 LysM domain L21SP4_RS08055 63a38a48891934d18019be642f616c78 228 Pfam PF13432 Tetratricopeptide repeat 25 86 1.8E-9 T 22-04-2016 L21SP4_RS08055 63a38a48891934d18019be642f616c78 228 PANTHER PTHR34700 161 225 1.7E-12 T 22-04-2016 L21SP4_RS08055 63a38a48891934d18019be642f616c78 228 SUPERFAMILY SSF48452 22 128 9.87E-10 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS03145 843959a25cf09438aafd3a9820a66198 295 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 270 292 0.0023 T 22-04-2016 IPR013424 PEP-CTERM protein-sorting domain L21SP4_RS05775 81ed561840225f811844ba977db783c9 150 Gene3D G3DSA:3.40.5.10 4 53 9.8E-21 T 22-04-2016 IPR020070 Ribosomal protein L9, N-terminal L21SP4_RS05775 81ed561840225f811844ba977db783c9 150 Gene3D G3DSA:3.10.430.100 62 150 1.4E-27 T 22-04-2016 IPR020069 Ribosomal protein L9, C-terminal L21SP4_RS05775 81ed561840225f811844ba977db783c9 150 TIGRFAM TIGR00158 L9: ribosomal protein bL9 5 150 1.6E-41 T 22-04-2016 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS05775 81ed561840225f811844ba977db783c9 150 SUPERFAMILY SSF55658 4 56 3.49E-16 T 22-04-2016 IPR009027 Ribosomal protein L9/RNase H1, N-terminal L21SP4_RS05775 81ed561840225f811844ba977db783c9 150 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 3 150 24.692 T 22-04-2016 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS05775 81ed561840225f811844ba977db783c9 150 SUPERFAMILY SSF55653 59 150 1.57E-24 T 22-04-2016 IPR020069 Ribosomal protein L9, C-terminal L21SP4_RS05775 81ed561840225f811844ba977db783c9 150 Pfam PF01281 Ribosomal protein L9, N-terminal domain 4 48 2.5E-19 T 22-04-2016 IPR020070 Ribosomal protein L9, N-terminal L21SP4_RS05775 81ed561840225f811844ba977db783c9 150 ProSitePatterns PS00651 Ribosomal protein L9 signature. 15 42 - T 22-04-2016 IPR020070 Ribosomal protein L9, N-terminal L21SP4_RS05775 81ed561840225f811844ba977db783c9 150 PANTHER PTHR21368 4 150 6.1E-40 T 22-04-2016 IPR000244 Ribosomal protein L9 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS05775 81ed561840225f811844ba977db783c9 150 Pfam PF03948 Ribosomal protein L9, C-terminal domain 65 149 3.2E-26 T 22-04-2016 IPR020069 Ribosomal protein L9, C-terminal L21SP4_RS10630 a51316a16fb78d22e63c1a0720d3a8a8 382 SUPERFAMILY SSF51726 1 381 4.71E-39 T 22-04-2016 L21SP4_RS10630 a51316a16fb78d22e63c1a0720d3a8a8 382 Gene3D G3DSA:3.20.20.210 1 378 9.5E-49 T 22-04-2016 L21SP4_RS10630 a51316a16fb78d22e63c1a0720d3a8a8 382 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 105 377 7.1E-21 T 22-04-2016 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 L21SP4_RS10175 3052c5c8ffe493a8b8b2e7b6e33125ff 212 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 15 98 9.3E-28 T 22-04-2016 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 L21SP4_RS10175 3052c5c8ffe493a8b8b2e7b6e33125ff 212 SUPERFAMILY SSF54719 101 211 6.15E-39 T 22-04-2016 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 L21SP4_RS10175 3052c5c8ffe493a8b8b2e7b6e33125ff 212 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 174 181 - T 22-04-2016 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 L21SP4_RS10175 3052c5c8ffe493a8b8b2e7b6e33125ff 212 Gene3D G3DSA:1.10.287.990 34 98 1.6E-20 T 22-04-2016 L21SP4_RS10175 3052c5c8ffe493a8b8b2e7b6e33125ff 212 PRINTS PR01703 Manganese superoxide dismutase signature 18 29 1.1E-22 T 22-04-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 L21SP4_RS10175 3052c5c8ffe493a8b8b2e7b6e33125ff 212 PRINTS PR01703 Manganese superoxide dismutase signature 82 95 1.1E-22 T 22-04-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 L21SP4_RS10175 3052c5c8ffe493a8b8b2e7b6e33125ff 212 PRINTS PR01703 Manganese superoxide dismutase signature 172 184 1.1E-22 T 22-04-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 L21SP4_RS10175 3052c5c8ffe493a8b8b2e7b6e33125ff 212 PRINTS PR01703 Manganese superoxide dismutase signature 39 52 1.1E-22 T 22-04-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 L21SP4_RS10175 3052c5c8ffe493a8b8b2e7b6e33125ff 212 PRINTS PR01703 Manganese superoxide dismutase signature 135 143 1.1E-22 T 22-04-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 L21SP4_RS10175 3052c5c8ffe493a8b8b2e7b6e33125ff 212 PANTHER PTHR11404 18 212 1.4E-92 T 22-04-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 L21SP4_RS10175 3052c5c8ffe493a8b8b2e7b6e33125ff 212 PANTHER PTHR11404:SF8 18 212 1.4E-92 T 22-04-2016 L21SP4_RS10175 3052c5c8ffe493a8b8b2e7b6e33125ff 212 SUPERFAMILY SSF46609 14 100 8.25E-33 T 22-04-2016 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 L21SP4_RS10175 3052c5c8ffe493a8b8b2e7b6e33125ff 212 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 106 206 9.3E-33 T 22-04-2016 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 L21SP4_RS10175 3052c5c8ffe493a8b8b2e7b6e33125ff 212 PIRSF PIRSF000349 6 212 1.4E-74 T 22-04-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 L21SP4_RS08790 32ceb5e8d991292b54822899bc4cac2c 746 Pfam PF11175 Protein of unknown function (DUF2961) 262 485 8.3E-59 T 22-04-2016 IPR021345 Protein of unknown function DUF2961 L21SP4_RS03195 a75357ad93c0f510706d2c19c51c4af4 593 ProSitePatterns PS00211 ABC transporters family signature. 403 417 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 L21SP4_RS03195 a75357ad93c0f510706d2c19c51c4af4 593 SMART SM00382 28 192 2.6E-19 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS03195 a75357ad93c0f510706d2c19c51c4af4 593 SMART SM00382 306 477 2.9E-15 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS03195 a75357ad93c0f510706d2c19c51c4af4 593 Pfam PF12848 ABC transporter 186 253 1.4E-7 T 22-04-2016 IPR032781 ABC-transporter extension domain L21SP4_RS03195 a75357ad93c0f510706d2c19c51c4af4 593 PANTHER PTHR19211 1 528 2.0E-196 T 22-04-2016 L21SP4_RS03195 a75357ad93c0f510706d2c19c51c4af4 593 Pfam PF00005 ABC transporter 19 147 2.0E-26 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 L21SP4_RS03195 a75357ad93c0f510706d2c19c51c4af4 593 Pfam PF00005 ABC transporter 298 431 1.5E-23 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 L21SP4_RS03195 a75357ad93c0f510706d2c19c51c4af4 593 Pfam PF16326 ABC transporter C-terminal domain 518 587 4.7E-18 T 22-04-2016 IPR032524 ABC transporter Uup, C-terminal GO:0003677 L21SP4_RS03195 a75357ad93c0f510706d2c19c51c4af4 593 SUPERFAMILY SSF52540 275 480 1.39E-46 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS03195 a75357ad93c0f510706d2c19c51c4af4 593 PANTHER PTHR19211:SF45 1 528 2.0E-196 T 22-04-2016 L21SP4_RS03195 a75357ad93c0f510706d2c19c51c4af4 593 Gene3D G3DSA:3.40.50.300 3 233 5.9E-51 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS03195 a75357ad93c0f510706d2c19c51c4af4 593 Gene3D G3DSA:3.40.50.300 282 512 1.2E-46 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS03195 a75357ad93c0f510706d2c19c51c4af4 593 SUPERFAMILY SSF52540 4 198 7.52E-51 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS03990 d05ed296deaf25b1150f95e60b1b1493 297 Pfam PF00294 pfkB family carbohydrate kinase 16 266 4.2E-30 T 22-04-2016 IPR011611 Carbohydrate kinase PfkB L21SP4_RS03990 d05ed296deaf25b1150f95e60b1b1493 297 PANTHER PTHR10584 1 294 4.6E-46 T 22-04-2016 L21SP4_RS03990 d05ed296deaf25b1150f95e60b1b1493 297 SUPERFAMILY SSF53613 2 274 3.59E-50 T 22-04-2016 IPR029056 Ribokinase-like L21SP4_RS03990 d05ed296deaf25b1150f95e60b1b1493 297 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 226 239 - T 22-04-2016 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 L21SP4_RS03990 d05ed296deaf25b1150f95e60b1b1493 297 Gene3D G3DSA:3.40.1190.20 2 289 2.1E-48 T 22-04-2016 IPR029056 Ribokinase-like L21SP4_RS03990 d05ed296deaf25b1150f95e60b1b1493 297 PANTHER PTHR10584:SF179 1 294 4.6E-46 T 22-04-2016 L21SP4_RS10835 bd857cd216ca7f3685c9972cd9881f56 107 Pfam PF05534 HicB family 60 103 6.3E-11 T 22-04-2016 IPR008651 Uncharacterised protein family HicB L21SP4_RS10835 bd857cd216ca7f3685c9972cd9881f56 107 SUPERFAMILY SSF143100 6 71 2.88E-12 T 22-04-2016 L21SP4_RS10835 bd857cd216ca7f3685c9972cd9881f56 107 SUPERFAMILY SSF47598 71 107 6.67E-6 T 22-04-2016 IPR010985 Ribbon-helix-helix GO:0006355 L21SP4_RS09325 687d9d0215add9e6c127341e58e9f922 144 Pfam PF01850 PIN domain 3 132 3.9E-12 T 22-04-2016 IPR002716 PIN domain L21SP4_RS09325 687d9d0215add9e6c127341e58e9f922 144 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 3 139 10.247 T 22-04-2016 IPR022907 VapC family GO:0004540 L21SP4_RS09325 687d9d0215add9e6c127341e58e9f922 144 SUPERFAMILY SSF88723 3 136 5.61E-17 T 22-04-2016 IPR029060 PIN domain-like L21SP4_RS09325 687d9d0215add9e6c127341e58e9f922 144 Gene3D G3DSA:3.40.50.1010 2 134 1.5E-7 T 22-04-2016 IPR029060 PIN domain-like L21SP4_RS11845 a4f709974f6acaf3ac64ab23887a1096 275 Gene3D G3DSA:2.60.120.500 129 275 2.7E-68 T 22-04-2016 IPR027447 5-keto-4-deoxyuronate isomerase, C-terminal domain KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507|UniPathway: UPA00545 L21SP4_RS11845 a4f709974f6acaf3ac64ab23887a1096 275 SUPERFAMILY SSF51182 1 259 7.12E-92 T 22-04-2016 IPR011051 RmlC-like cupin domain L21SP4_RS11845 a4f709974f6acaf3ac64ab23887a1096 275 Gene3D G3DSA:2.60.120.520 20 128 1.1E-40 T 22-04-2016 IPR027449 5-keto-4-deoxyuronate isomerase, N-terminal domain KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507|UniPathway: UPA00545 L21SP4_RS11845 a4f709974f6acaf3ac64ab23887a1096 275 PANTHER PTHR38461 1 275 8.6E-129 T 22-04-2016 L21SP4_RS11845 a4f709974f6acaf3ac64ab23887a1096 275 Hamap MF_00687 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase [kduI]. 1 275 49.04 T 22-04-2016 IPR007045 5-keto 4-deoxyuronate isomerase GO:0008697|GO:0045490 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507|UniPathway: UPA00545 L21SP4_RS11845 a4f709974f6acaf3ac64ab23887a1096 275 PIRSF PIRSF006625 1 275 6.8E-116 T 22-04-2016 IPR007045 5-keto 4-deoxyuronate isomerase GO:0008697|GO:0045490 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507|UniPathway: UPA00545 L21SP4_RS11845 a4f709974f6acaf3ac64ab23887a1096 275 Pfam PF04962 KduI/IolB family 37 266 6.2E-31 T 22-04-2016 IPR021120 KduI/IolB isomerase GO:0016861 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507|UniPathway: UPA00545 L21SP4_RS05575 cca06e84eca5f99c988aaa81652d2d6a 330 SUPERFAMILY SSF51658 8 313 2.75E-59 T 22-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain L21SP4_RS05575 cca06e84eca5f99c988aaa81652d2d6a 330 PANTHER PTHR12110:SF17 1 83 1.1E-72 T 22-04-2016 L21SP4_RS05575 cca06e84eca5f99c988aaa81652d2d6a 330 PANTHER PTHR12110:SF17 101 315 1.1E-72 T 22-04-2016 L21SP4_RS05575 cca06e84eca5f99c988aaa81652d2d6a 330 Pfam PF01261 Xylose isomerase-like TIM barrel 22 271 1.1E-39 T 22-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain L21SP4_RS05575 cca06e84eca5f99c988aaa81652d2d6a 330 Pfam PF07582 AP endonuclease family 2 C terminus 273 327 9.4E-25 T 22-04-2016 IPR011418 AP endonuclease, family 2, C-terminal L21SP4_RS05575 cca06e84eca5f99c988aaa81652d2d6a 330 PANTHER PTHR12110 1 83 1.1E-72 T 22-04-2016 L21SP4_RS05575 cca06e84eca5f99c988aaa81652d2d6a 330 PANTHER PTHR12110 101 315 1.1E-72 T 22-04-2016 L21SP4_RS05575 cca06e84eca5f99c988aaa81652d2d6a 330 Gene3D G3DSA:3.20.20.150 3 315 1.1E-79 T 22-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain L21SP4_RS01075 7f4dc1af467b77e0c7ce396faabd8e62 394 SUPERFAMILY SSF51735 3 100 1.37E-21 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS01075 7f4dc1af467b77e0c7ce396faabd8e62 394 Gene3D G3DSA:3.30.360.10 158 384 3.5E-11 T 22-04-2016 L21SP4_RS01075 7f4dc1af467b77e0c7ce396faabd8e62 394 SUPERFAMILY SSF55347 168 314 1.14E-13 T 22-04-2016 L21SP4_RS01075 7f4dc1af467b77e0c7ce396faabd8e62 394 PANTHER PTHR22604:SF2 5 101 3.2E-35 T 22-04-2016 L21SP4_RS01075 7f4dc1af467b77e0c7ce396faabd8e62 394 PANTHER PTHR22604:SF2 127 391 3.2E-35 T 22-04-2016 L21SP4_RS01075 7f4dc1af467b77e0c7ce396faabd8e62 394 PANTHER PTHR22604 5 101 3.2E-35 T 22-04-2016 L21SP4_RS01075 7f4dc1af467b77e0c7ce396faabd8e62 394 PANTHER PTHR22604 127 391 3.2E-35 T 22-04-2016 L21SP4_RS01075 7f4dc1af467b77e0c7ce396faabd8e62 394 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 7 100 1.3E-14 T 22-04-2016 IPR000683 Oxidoreductase, N-terminal GO:0016491 L21SP4_RS01075 7f4dc1af467b77e0c7ce396faabd8e62 394 Gene3D G3DSA:3.40.50.720 3 157 4.7E-27 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS11955 8742af37d564345cb17a30ad3cdec458 270 PANTHER PTHR21581 29 268 5.8E-60 T 22-04-2016 L21SP4_RS11955 8742af37d564345cb17a30ad3cdec458 270 SUPERFAMILY SSF56601 25 268 1.79E-63 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like L21SP4_RS11955 8742af37d564345cb17a30ad3cdec458 270 Gene3D G3DSA:3.40.710.10 29 268 2.8E-79 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like L21SP4_RS11955 8742af37d564345cb17a30ad3cdec458 270 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 30 250 4.3E-52 T 22-04-2016 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 L21SP4_RS11955 8742af37d564345cb17a30ad3cdec458 270 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 133 146 3.7E-14 T 22-04-2016 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 L21SP4_RS11955 8742af37d564345cb17a30ad3cdec458 270 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 53 64 3.7E-14 T 22-04-2016 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 L21SP4_RS11955 8742af37d564345cb17a30ad3cdec458 270 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 106 123 3.7E-14 T 22-04-2016 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 L21SP4_RS02760 af738954a8e9194233b4aec1b612c284 421 PANTHER PTHR30465 175 420 7.7E-71 T 22-04-2016 L21SP4_RS02760 af738954a8e9194233b4aec1b612c284 421 PANTHER PTHR30465:SF24 175 420 7.7E-71 T 22-04-2016 L21SP4_RS02760 af738954a8e9194233b4aec1b612c284 421 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 229 419 2.0E-35 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 L21SP4_RS02760 af738954a8e9194233b4aec1b612c284 421 Gene3D G3DSA:1.10.3720.10 207 416 7.8E-18 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 L21SP4_RS02760 af738954a8e9194233b4aec1b612c284 421 SUPERFAMILY SSF161098 205 403 8.24E-17 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 L21SP4_RS05410 ad40da9701676dfaa9fe63d21307f853 558 Gene3D G3DSA:2.170.130.10 6 43 7.2E-15 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 L21SP4_RS05410 ad40da9701676dfaa9fe63d21307f853 558 Gene3D G3DSA:2.40.170.20 44 558 4.6E-80 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 L21SP4_RS05410 ad40da9701676dfaa9fe63d21307f853 558 SUPERFAMILY SSF56935 7 558 1.06E-88 T 22-04-2016 L21SP4_RS05410 ad40da9701676dfaa9fe63d21307f853 558 Pfam PF00593 TonB dependent receptor 318 557 2.1E-24 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 L21SP4_RS05410 ad40da9701676dfaa9fe63d21307f853 558 PANTHER PTHR32552 9 558 4.9E-51 T 22-04-2016 L21SP4_RS05410 ad40da9701676dfaa9fe63d21307f853 558 Pfam PF07715 TonB-dependent Receptor Plug Domain 2 41 3.8E-8 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 L21SP4_RS05410 ad40da9701676dfaa9fe63d21307f853 558 PANTHER PTHR32552:SF0 9 558 4.9E-51 T 22-04-2016 L21SP4_RS08420 f5a226b597463fd0d1c3d2298ac55754 156 Gene3D G3DSA:1.10.455.10 7 156 2.9E-63 T 22-04-2016 IPR023798 Ribosomal protein S7 domain L21SP4_RS08420 f5a226b597463fd0d1c3d2298ac55754 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 34.62 T 22-04-2016 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 L21SP4_RS08420 f5a226b597463fd0d1c3d2298ac55754 156 SUPERFAMILY SSF47973 4 149 5.49E-57 T 22-04-2016 IPR023798 Ribosomal protein S7 domain L21SP4_RS08420 f5a226b597463fd0d1c3d2298ac55754 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 3.0E-62 T 22-04-2016 IPR023798 Ribosomal protein S7 domain L21SP4_RS08420 f5a226b597463fd0d1c3d2298ac55754 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 1.1E-66 T 22-04-2016 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 L21SP4_RS08420 f5a226b597463fd0d1c3d2298ac55754 156 PANTHER PTHR11205 1 156 2.7E-79 T 22-04-2016 IPR000235 Ribosomal protein S5/S7 GO:0006412 L21SP4_RS08420 f5a226b597463fd0d1c3d2298ac55754 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 22-04-2016 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 L21SP4_RS08420 f5a226b597463fd0d1c3d2298ac55754 156 PIRSF PIRSF002122 3 156 1.7E-58 T 22-04-2016 IPR000235 Ribosomal protein S5/S7 GO:0006412 L21SP4_RS11565 a3a3015827807db7d329ec2d73ac884f 464 SMART SM00228 117 191 2.2E-8 T 22-04-2016 IPR001478 PDZ domain GO:0005515 L21SP4_RS11565 a3a3015827807db7d329ec2d73ac884f 464 SMART SM00228 195 276 7.0E-6 T 22-04-2016 IPR001478 PDZ domain GO:0005515 L21SP4_RS11565 a3a3015827807db7d329ec2d73ac884f 464 PANTHER PTHR22939 221 438 3.4E-47 T 22-04-2016 L21SP4_RS11565 a3a3015827807db7d329ec2d73ac884f 464 Gene3D G3DSA:2.30.42.10 203 289 7.8E-19 T 22-04-2016 IPR001478 PDZ domain GO:0005515 L21SP4_RS11565 a3a3015827807db7d329ec2d73ac884f 464 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 130 187 3.8E-6 T 22-04-2016 IPR001478 PDZ domain GO:0005515 L21SP4_RS11565 a3a3015827807db7d329ec2d73ac884f 464 SUPERFAMILY SSF50156 219 296 9.07E-16 T 22-04-2016 IPR001478 PDZ domain GO:0005515 L21SP4_RS11565 a3a3015827807db7d329ec2d73ac884f 464 Pfam PF13180 PDZ domain 220 284 7.8E-8 T 22-04-2016 IPR001478 PDZ domain GO:0005515 L21SP4_RS11565 a3a3015827807db7d329ec2d73ac884f 464 PANTHER PTHR22939:SF78 221 438 3.4E-47 T 22-04-2016 L21SP4_RS11565 a3a3015827807db7d329ec2d73ac884f 464 SUPERFAMILY SSF50156 91 190 3.94E-13 T 22-04-2016 IPR001478 PDZ domain GO:0005515 L21SP4_RS11565 a3a3015827807db7d329ec2d73ac884f 464 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 3 437 2.4E-82 T 22-04-2016 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 L21SP4_RS11565 a3a3015827807db7d329ec2d73ac884f 464 Pfam PF02163 Peptidase family M50 9 422 8.0E-57 T 22-04-2016 IPR008915 Peptidase M50 GO:0004222|GO:0006508 L21SP4_RS11565 a3a3015827807db7d329ec2d73ac884f 464 Gene3D G3DSA:2.30.42.10 95 190 2.2E-14 T 22-04-2016 IPR001478 PDZ domain GO:0005515 L21SP4_RS06895 65681af2097651377cc51fd34520b270 162 Gene3D G3DSA:2.40.280.10 14 133 1.3E-46 T 22-04-2016 IPR023620 Small protein B L21SP4_RS06895 65681af2097651377cc51fd34520b270 162 SUPERFAMILY SSF74982 13 138 4.45E-46 T 22-04-2016 IPR023620 Small protein B L21SP4_RS06895 65681af2097651377cc51fd34520b270 162 TIGRFAM TIGR00086 smpB: SsrA-binding protein 15 155 1.6E-53 T 22-04-2016 IPR000037 SsrA-binding protein GO:0003723 L21SP4_RS06895 65681af2097651377cc51fd34520b270 162 ProSitePatterns PS01317 SsrA-binding protein. 33 45 - T 22-04-2016 IPR020081 SsrA-binding protein, conserved site L21SP4_RS06895 65681af2097651377cc51fd34520b270 162 Hamap MF_00023 SsrA-binding protein [smpB]. 1 162 64.564 T 22-04-2016 IPR000037 SsrA-binding protein GO:0003723 L21SP4_RS06895 65681af2097651377cc51fd34520b270 162 PANTHER PTHR30308 2 161 8.8E-71 T 22-04-2016 L21SP4_RS06895 65681af2097651377cc51fd34520b270 162 Pfam PF01668 SmpB protein 15 78 1.5E-23 T 22-04-2016 IPR000037 SsrA-binding protein GO:0003723 L21SP4_RS06895 65681af2097651377cc51fd34520b270 162 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 15 117 1.0E-30 T 22-04-2016 IPR000037 SsrA-binding protein GO:0003723 L21SP4_RS06895 65681af2097651377cc51fd34520b270 162 PANTHER PTHR30308:SF2 2 161 8.8E-71 T 22-04-2016 L21SP4_RS00730 acab41ea60a71d01e540b0ceac147493 304 PANTHER PTHR30269:SF15 10 105 1.9E-47 T 22-04-2016 L21SP4_RS00730 acab41ea60a71d01e540b0ceac147493 304 PANTHER PTHR30269:SF15 122 302 1.9E-47 T 22-04-2016 L21SP4_RS00730 acab41ea60a71d01e540b0ceac147493 304 PANTHER PTHR30269 10 105 1.9E-47 T 22-04-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 L21SP4_RS00730 acab41ea60a71d01e540b0ceac147493 304 PANTHER PTHR30269 122 302 1.9E-47 T 22-04-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 L21SP4_RS00730 acab41ea60a71d01e540b0ceac147493 304 Pfam PF01925 Sulfite exporter TauE/SafE 17 288 2.5E-47 T 22-04-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 L21SP4_RS01145 f723ca78cc9b30c37e3129cfdd40ccb1 406 Pfam PF00999 Sodium/hydrogen exchanger family 10 390 3.7E-27 T 22-04-2016 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 L21SP4_RS01145 f723ca78cc9b30c37e3129cfdd40ccb1 406 PANTHER PTHR32507:SF10 7 405 2.3E-63 T 22-04-2016 L21SP4_RS01145 f723ca78cc9b30c37e3129cfdd40ccb1 406 PANTHER PTHR32507 7 405 2.3E-63 T 22-04-2016 L21SP4_RS01815 1a16e8b277f13ee02ffc388409e957d0 286 Pfam PF02311 AraC-like ligand binding domain 31 90 8.8E-9 T 22-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 L21SP4_RS01815 1a16e8b277f13ee02ffc388409e957d0 286 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 232 274 - T 22-04-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 L21SP4_RS01815 1a16e8b277f13ee02ffc388409e957d0 286 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 247 262 5.7E-6 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 L21SP4_RS01815 1a16e8b277f13ee02ffc388409e957d0 286 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 262 278 5.7E-6 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 L21SP4_RS01815 1a16e8b277f13ee02ffc388409e957d0 286 PANTHER PTHR11019:SF65 34 286 1.2E-21 T 22-04-2016 L21SP4_RS01815 1a16e8b277f13ee02ffc388409e957d0 286 SUPERFAMILY SSF51215 30 87 1.44E-10 T 22-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 L21SP4_RS01815 1a16e8b277f13ee02ffc388409e957d0 286 Pfam PF12833 Helix-turn-helix domain 203 280 1.8E-20 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP4_RS01815 1a16e8b277f13ee02ffc388409e957d0 286 PANTHER PTHR11019 34 286 1.2E-21 T 22-04-2016 L21SP4_RS01815 1a16e8b277f13ee02ffc388409e957d0 286 SMART SM00342 194 278 4.0E-22 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP4_RS01815 1a16e8b277f13ee02ffc388409e957d0 286 SUPERFAMILY SSF46689 231 282 1.39E-12 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS01815 1a16e8b277f13ee02ffc388409e957d0 286 Gene3D G3DSA:2.60.120.10 21 82 3.7E-8 T 22-04-2016 IPR014710 RmlC-like jelly roll fold L21SP4_RS01815 1a16e8b277f13ee02ffc388409e957d0 286 Gene3D G3DSA:1.10.10.60 230 280 5.2E-19 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS11600 2b7bd573315efb62d7cdace262ad52cb 166 Gene3D G3DSA:1.20.1260.10 1 162 4.6E-53 T 22-04-2016 IPR012347 Ferritin-related L21SP4_RS11600 2b7bd573315efb62d7cdace262ad52cb 166 Pfam PF00210 Ferritin-like domain 8 143 8.4E-39 T 22-04-2016 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 L21SP4_RS11600 2b7bd573315efb62d7cdace262ad52cb 166 SUPERFAMILY SSF47240 1 161 2.71E-53 T 22-04-2016 IPR009078 Ferritin-like superfamily L21SP4_RS11600 2b7bd573315efb62d7cdace262ad52cb 166 PANTHER PTHR11431:SF4 3 164 1.9E-35 T 22-04-2016 L21SP4_RS11600 2b7bd573315efb62d7cdace262ad52cb 166 PANTHER PTHR11431 3 164 1.9E-35 T 22-04-2016 IPR001519 Ferritin GO:0006826|GO:0006879|GO:0008199 L21SP4_RS01220 33bda4d4afab960d40598982447ce53f 319 Pfam PF00005 ABC transporter 19 161 1.9E-27 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 L21SP4_RS01220 33bda4d4afab960d40598982447ce53f 319 SMART SM00382 27 208 7.4E-12 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS01220 33bda4d4afab960d40598982447ce53f 319 SUPERFAMILY SSF52540 2 222 1.93E-56 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS01220 33bda4d4afab960d40598982447ce53f 319 PANTHER PTHR24220 292 301 6.6E-83 T 22-04-2016 L21SP4_RS01220 33bda4d4afab960d40598982447ce53f 319 PANTHER PTHR24220 3 264 6.6E-83 T 22-04-2016 L21SP4_RS01220 33bda4d4afab960d40598982447ce53f 319 PANTHER PTHR24220:SF160 292 301 6.6E-83 T 22-04-2016 L21SP4_RS01220 33bda4d4afab960d40598982447ce53f 319 PANTHER PTHR24220:SF160 3 264 6.6E-83 T 22-04-2016 L21SP4_RS01220 33bda4d4afab960d40598982447ce53f 319 Gene3D G3DSA:3.40.50.300 1 224 6.4E-62 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS05475 0f23df8e89b1cca0350c79c1d9c55d9d 258 PANTHER PTHR12277 45 254 1.3E-64 T 22-04-2016 L21SP4_RS05475 0f23df8e89b1cca0350c79c1d9c55d9d 258 Gene3D G3DSA:3.40.50.1820 48 241 1.2E-36 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold L21SP4_RS05475 0f23df8e89b1cca0350c79c1d9c55d9d 258 Pfam PF12146 Serine aminopeptidase, S33 67 173 7.9E-11 T 22-04-2016 IPR022742 Serine aminopeptidase, S33 L21SP4_RS05475 0f23df8e89b1cca0350c79c1d9c55d9d 258 SUPERFAMILY SSF53474 45 251 2.08E-39 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold L21SP4_RS05430 e74ddba61da3c6df88e43d2a2b5e66a3 296 Gene3D G3DSA:3.40.50.1980 156 292 2.2E-20 T 22-04-2016 L21SP4_RS05430 e74ddba61da3c6df88e43d2a2b5e66a3 296 SUPERFAMILY SSF53807 34 291 3.45E-54 T 22-04-2016 L21SP4_RS05430 e74ddba61da3c6df88e43d2a2b5e66a3 296 PANTHER PTHR30535 32 293 3.3E-52 T 22-04-2016 L21SP4_RS05430 e74ddba61da3c6df88e43d2a2b5e66a3 296 Pfam PF01497 Periplasmic binding protein 38 267 2.9E-25 T 22-04-2016 IPR002491 ABC transporter periplasmic binding domain GO:0005488 L21SP4_RS05430 e74ddba61da3c6df88e43d2a2b5e66a3 296 Gene3D G3DSA:3.40.50.1980 34 151 2.3E-33 T 22-04-2016 L21SP4_RS04775 cf5c8e5ee41d37836f0010f771dd7133 271 Gene3D G3DSA:3.90.1070.10 105 174 1.6E-13 T 22-04-2016 L21SP4_RS04775 cf5c8e5ee41d37836f0010f771dd7133 271 SUPERFAMILY SSF56784 3 238 3.37E-24 T 22-04-2016 IPR023214 HAD-like domain L21SP4_RS04775 cf5c8e5ee41d37836f0010f771dd7133 271 Pfam PF05116 Sucrose-6F-phosphate phosphohydrolase 5 266 5.1E-46 T 22-04-2016 IPR006380 Sucrose-phosphatase, N-terminal L21SP4_RS04775 cf5c8e5ee41d37836f0010f771dd7133 271 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 6 219 1.1E-18 T 22-04-2016 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: REACT_17015 L21SP4_RS04775 cf5c8e5ee41d37836f0010f771dd7133 271 Gene3D G3DSA:3.40.50.1000 175 266 2.3E-25 T 22-04-2016 IPR023214 HAD-like domain L21SP4_RS04775 cf5c8e5ee41d37836f0010f771dd7133 271 Gene3D G3DSA:3.40.50.1000 5 87 2.3E-25 T 22-04-2016 IPR023214 HAD-like domain L21SP4_RS09690 38cc06e8c4e999e861bf6b989e563ddb 133 PANTHER PTHR34580 1 126 9.0E-24 T 22-04-2016 L21SP4_RS09690 38cc06e8c4e999e861bf6b989e563ddb 133 PANTHER PTHR34580:SF1 1 126 9.0E-24 T 22-04-2016 L21SP4_RS09690 38cc06e8c4e999e861bf6b989e563ddb 133 Pfam PF13280 WYL domain 2 127 2.6E-26 T 22-04-2016 IPR026881 WYL domain L21SP4_RS00330 c6652f0e7a6972df4262099c29db2cad 307 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 20 305 5.6E-64 T 22-04-2016 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00276|UniPathway: UPA00277 L21SP4_RS00330 c6652f0e7a6972df4262099c29db2cad 307 PANTHER PTHR22749 22 306 1.4E-85 T 22-04-2016 IPR023468 Riboflavin kinase KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|UniPathway: UPA00276 L21SP4_RS00330 c6652f0e7a6972df4262099c29db2cad 307 PIRSF PIRSF004491 3 307 5.6E-81 T 22-04-2016 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00276|UniPathway: UPA00277 L21SP4_RS00330 c6652f0e7a6972df4262099c29db2cad 307 Gene3D G3DSA:2.40.30.30 180 306 1.7E-33 T 22-04-2016 IPR023465 Riboflavin kinase domain GO:0008531|GO:0009231 L21SP4_RS00330 c6652f0e7a6972df4262099c29db2cad 307 SMART SM00904 183 307 3.8E-39 T 22-04-2016 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 L21SP4_RS00330 c6652f0e7a6972df4262099c29db2cad 307 Pfam PF01687 Riboflavin kinase 184 306 1.8E-28 T 22-04-2016 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 L21SP4_RS00330 c6652f0e7a6972df4262099c29db2cad 307 Gene3D G3DSA:3.40.50.620 14 179 3.4E-49 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP4_RS00330 c6652f0e7a6972df4262099c29db2cad 307 SUPERFAMILY SSF52374 19 175 2.68E-24 T 22-04-2016 L21SP4_RS00330 c6652f0e7a6972df4262099c29db2cad 307 Pfam PF06574 FAD synthetase 19 167 1.5E-36 T 22-04-2016 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00276|UniPathway: UPA00277 L21SP4_RS00330 c6652f0e7a6972df4262099c29db2cad 307 PANTHER PTHR22749:SF0 22 306 1.4E-85 T 22-04-2016 L21SP4_RS00330 c6652f0e7a6972df4262099c29db2cad 307 SUPERFAMILY SSF82114 174 306 1.92E-33 T 22-04-2016 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 L21SP4_RS05500 7c85f67cb9e70723421817a8a49b9eab 245 SUPERFAMILY SSF53271 70 243 1.62E-31 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like L21SP4_RS05500 7c85f67cb9e70723421817a8a49b9eab 245 Pfam PF00156 Phosphoribosyl transferase domain 154 243 3.1E-9 T 22-04-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 L21SP4_RS05500 7c85f67cb9e70723421817a8a49b9eab 245 PANTHER PTHR11907 18 244 5.7E-45 T 22-04-2016 L21SP4_RS05500 7c85f67cb9e70723421817a8a49b9eab 245 PANTHER PTHR11907:SF9 18 244 5.7E-45 T 22-04-2016 L21SP4_RS05500 7c85f67cb9e70723421817a8a49b9eab 245 Gene3D G3DSA:3.40.50.2020 71 244 9.1E-28 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like L21SP4_RS06485 f99c8244f241fad04e9362b8f3de3250 766 Gene3D G3DSA:2.60.120.260 629 766 9.7E-6 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS06485 f99c8244f241fad04e9362b8f3de3250 766 Gene3D G3DSA:3.50.50.60 375 452 4.5E-24 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP4_RS06485 f99c8244f241fad04e9362b8f3de3250 766 Gene3D G3DSA:3.50.50.60 267 268 4.5E-24 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP4_RS06485 f99c8244f241fad04e9362b8f3de3250 766 Gene3D G3DSA:3.50.50.60 26 174 4.5E-24 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP4_RS06485 f99c8244f241fad04e9362b8f3de3250 766 SUPERFAMILY SSF49785 629 766 7.04E-6 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS06485 f99c8244f241fad04e9362b8f3de3250 766 Pfam PF12831 FAD dependent oxidoreductase 30 451 3.0E-88 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP4_RS06485 f99c8244f241fad04e9362b8f3de3250 766 SUPERFAMILY SSF51905 26 183 2.66E-22 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP4_RS06485 f99c8244f241fad04e9362b8f3de3250 766 SUPERFAMILY SSF51905 378 429 2.66E-22 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP4_RS08010 e7bf8a0691c3ef0362e7c49fca8bfa2b 359 Pfam PF01699 Sodium/calcium exchanger protein 12 148 3.9E-11 T 22-04-2016 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: REACT_15518 L21SP4_RS08010 e7bf8a0691c3ef0362e7c49fca8bfa2b 359 Pfam PF01699 Sodium/calcium exchanger protein 213 355 5.3E-14 T 22-04-2016 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: REACT_15518 L21SP4_RS08010 e7bf8a0691c3ef0362e7c49fca8bfa2b 359 PANTHER PTHR10846 246 290 1.4E-13 T 22-04-2016 IPR004481 Sodium/potassium/calcium exchanger Reactome: REACT_15518 L21SP4_RS08010 e7bf8a0691c3ef0362e7c49fca8bfa2b 359 PANTHER PTHR10846:SF8 246 290 1.4E-13 T 22-04-2016 L21SP4_RS04740 60ba2875075a393355d78c34e9ac1dfa 178 Gene3D G3DSA:3.30.70.270 40 176 1.5E-35 T 22-04-2016 L21SP4_RS04740 60ba2875075a393355d78c34e9ac1dfa 178 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 39 172 4.8E-35 T 22-04-2016 IPR000160 GGDEF domain L21SP4_RS04740 60ba2875075a393355d78c34e9ac1dfa 178 PANTHER PTHR10799 1 143 4.5E-18 T 22-04-2016 L21SP4_RS04740 60ba2875075a393355d78c34e9ac1dfa 178 SMART SM00267 28 178 1.8E-33 T 22-04-2016 IPR000160 GGDEF domain L21SP4_RS04740 60ba2875075a393355d78c34e9ac1dfa 178 Pfam PF00990 Diguanylate cyclase, GGDEF domain 39 143 2.6E-31 T 22-04-2016 IPR000160 GGDEF domain L21SP4_RS04740 60ba2875075a393355d78c34e9ac1dfa 178 SUPERFAMILY SSF55073 43 177 4.08E-36 T 22-04-2016 IPR029787 Nucleotide cyclase L21SP4_RS04740 60ba2875075a393355d78c34e9ac1dfa 178 PANTHER PTHR10799:SF750 1 143 4.5E-18 T 22-04-2016 L21SP4_RS03295 11db9aa92d838c7884a68932cfb9441c 353 PANTHER PTHR35810 18 348 9.5E-133 T 22-04-2016 L21SP4_RS03295 11db9aa92d838c7884a68932cfb9441c 353 PIRSF PIRSF015268 17 353 6.4E-139 T 22-04-2016 IPR011204 Virulence protein RhuM-like L21SP4_RS03295 11db9aa92d838c7884a68932cfb9441c 353 Pfam PF13310 Virulence protein RhuM family 83 334 2.4E-108 T 22-04-2016 IPR011204 Virulence protein RhuM-like L21SP4_RS03295 11db9aa92d838c7884a68932cfb9441c 353 PANTHER PTHR35810:SF1 18 348 9.5E-133 T 22-04-2016 L21SP4_RS00540 e2a91c65aad29163d739dd345a4fc3de 176 PANTHER PTHR11839:SF9 4 167 2.8E-48 T 22-04-2016 L21SP4_RS00540 e2a91c65aad29163d739dd345a4fc3de 176 ProSitePatterns PS00893 Nudix box signature. 74 95 - T 22-04-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 L21SP4_RS00540 e2a91c65aad29163d739dd345a4fc3de 176 PRINTS PR00502 NUDIX hydrolase family signature 69 83 6.43E-5 T 22-04-2016 IPR020476 NUDIX hydrolase L21SP4_RS00540 e2a91c65aad29163d739dd345a4fc3de 176 PRINTS PR00502 NUDIX hydrolase family signature 83 98 6.43E-5 T 22-04-2016 IPR020476 NUDIX hydrolase L21SP4_RS00540 e2a91c65aad29163d739dd345a4fc3de 176 Pfam PF00293 NUDIX domain 39 152 1.5E-16 T 22-04-2016 IPR000086 NUDIX hydrolase domain GO:0016787 L21SP4_RS00540 e2a91c65aad29163d739dd345a4fc3de 176 Gene3D G3DSA:3.90.79.10 3 170 1.0E-48 T 22-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 L21SP4_RS00540 e2a91c65aad29163d739dd345a4fc3de 176 PANTHER PTHR11839 4 167 2.8E-48 T 22-04-2016 L21SP4_RS00540 e2a91c65aad29163d739dd345a4fc3de 176 SUPERFAMILY SSF55811 5 171 5.01E-44 T 22-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 L21SP4_RS03795 d7db77cef3fd35e60d492d1512f48442 492 SUPERFAMILY SSF53649 36 469 1.78E-123 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS03795 d7db77cef3fd35e60d492d1512f48442 492 Pfam PF00884 Sulfatase 36 353 4.3E-74 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS03795 d7db77cef3fd35e60d492d1512f48442 492 Pfam PF14707 C-terminal region of aryl-sulfatase 377 472 9.4E-8 T 22-04-2016 L21SP4_RS03795 d7db77cef3fd35e60d492d1512f48442 492 Gene3D G3DSA:3.40.720.10 36 366 1.8E-107 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS03795 d7db77cef3fd35e60d492d1512f48442 492 Gene3D G3DSA:3.30.1120.10 367 465 7.5E-14 T 22-04-2016 L21SP4_RS03795 d7db77cef3fd35e60d492d1512f48442 492 PANTHER PTHR10342 8 488 6.5E-147 T 22-04-2016 L21SP4_RS03795 d7db77cef3fd35e60d492d1512f48442 492 PANTHER PTHR10342:SF199 8 488 6.5E-147 T 22-04-2016 L21SP4_RS02745 015a7d603775695a3394113d167e729e 251 Pfam PF00121 Triosephosphate isomerase 5 247 4.9E-98 T 22-04-2016 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 L21SP4_RS02745 015a7d603775695a3394113d167e729e 251 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 5 240 4.9E-65 T 22-04-2016 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 L21SP4_RS02745 015a7d603775695a3394113d167e729e 251 ProSitePatterns PS00171 Triosephosphate isomerase active site. 165 175 - T 22-04-2016 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 L21SP4_RS02745 015a7d603775695a3394113d167e729e 251 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 2 250 42.42 T 22-04-2016 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 L21SP4_RS02745 015a7d603775695a3394113d167e729e 251 PANTHER PTHR21139 1 251 1.9E-132 T 22-04-2016 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 L21SP4_RS02745 015a7d603775695a3394113d167e729e 251 SUPERFAMILY SSF51351 1 250 1.57E-99 T 22-04-2016 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 L21SP4_RS02745 015a7d603775695a3394113d167e729e 251 Gene3D G3DSA:3.20.20.70 1 250 1.7E-112 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP4_RS00570 e576ca83f3acd19cec6f0fd898210d2e 135 Gene3D G3DSA:3.30.420.130 1 113 2.0E-36 T 22-04-2016 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis L21SP4_RS00570 e576ca83f3acd19cec6f0fd898210d2e 135 SUPERFAMILY SSF53146 1 119 1.1E-33 T 22-04-2016 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis L21SP4_RS00570 e576ca83f3acd19cec6f0fd898210d2e 135 PANTHER PTHR33937:SF2 1 130 5.3E-35 T 22-04-2016 L21SP4_RS00570 e576ca83f3acd19cec6f0fd898210d2e 135 PANTHER PTHR33937 1 130 5.3E-35 T 22-04-2016 L21SP4_RS00570 e576ca83f3acd19cec6f0fd898210d2e 135 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 13 102 9.4E-26 T 22-04-2016 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis L21SP4_RS10245 5ec4f9f8baf7d87ad424e7c56589d662 373 PANTHER PTHR30217 56 339 2.3E-28 T 22-04-2016 L21SP4_RS10245 5ec4f9f8baf7d87ad424e7c56589d662 373 PANTHER PTHR30217:SF9 56 339 2.3E-28 T 22-04-2016 L21SP4_RS10245 5ec4f9f8baf7d87ad424e7c56589d662 373 Pfam PF01136 Peptidase family U32 97 263 7.1E-10 T 22-04-2016 IPR001539 Peptidase U32 GO:0006508|GO:0008233 KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- L21SP4_RS01300 d79197085d1fe5855147f3c8e7e8246f 426 PANTHER PTHR30012:SF0 2 426 3.7E-143 T 22-04-2016 L21SP4_RS01300 d79197085d1fe5855147f3c8e7e8246f 426 PANTHER PTHR30012 2 426 3.7E-143 T 22-04-2016 L21SP4_RS01300 d79197085d1fe5855147f3c8e7e8246f 426 Pfam PF00482 Type II secretion system (T2SS), protein F 90 213 3.9E-31 T 22-04-2016 IPR018076 Type II secretion system F domain L21SP4_RS01300 d79197085d1fe5855147f3c8e7e8246f 426 Pfam PF00482 Type II secretion system (T2SS), protein F 295 417 1.4E-25 T 22-04-2016 IPR018076 Type II secretion system F domain L21SP4_RS01300 d79197085d1fe5855147f3c8e7e8246f 426 PRINTS PR00812 Bacterial general secretion pathway protein F signature 185 213 3.5E-22 T 22-04-2016 IPR003004 GspF/PilC family L21SP4_RS01300 d79197085d1fe5855147f3c8e7e8246f 426 PRINTS PR00812 Bacterial general secretion pathway protein F signature 86 98 3.5E-22 T 22-04-2016 IPR003004 GspF/PilC family L21SP4_RS01300 d79197085d1fe5855147f3c8e7e8246f 426 PRINTS PR00812 Bacterial general secretion pathway protein F signature 406 425 3.5E-22 T 22-04-2016 IPR003004 GspF/PilC family L21SP4_RS01300 d79197085d1fe5855147f3c8e7e8246f 426 PRINTS PR00812 Bacterial general secretion pathway protein F signature 390 404 3.5E-22 T 22-04-2016 IPR003004 GspF/PilC family L21SP4_RS08510 acd5fc6fe68840e9674fd33eb0596e3b 245 PANTHER PTHR10953 6 244 2.3E-66 T 22-04-2016 L21SP4_RS08510 acd5fc6fe68840e9674fd33eb0596e3b 245 Gene3D G3DSA:3.40.50.720 4 241 6.6E-66 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS08510 acd5fc6fe68840e9674fd33eb0596e3b 245 Pfam PF00899 ThiF family 7 237 2.0E-57 T 22-04-2016 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 L21SP4_RS08510 acd5fc6fe68840e9674fd33eb0596e3b 245 SUPERFAMILY SSF69572 5 242 1.44E-77 T 22-04-2016 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 L21SP4_RS04890 80e4da90e101481bdbae28828a25cfa6 412 Gene3D G3DSA:3.30.750.44 48 105 9.4E-9 T 22-04-2016 L21SP4_RS04890 80e4da90e101481bdbae28828a25cfa6 412 PANTHER PTHR32060 59 381 7.8E-117 T 22-04-2016 L21SP4_RS04890 80e4da90e101481bdbae28828a25cfa6 412 Pfam PF03572 Peptidase family S41 200 363 3.6E-54 T 22-04-2016 IPR005151 Tail specific protease GO:0006508|GO:0008236 L21SP4_RS04890 80e4da90e101481bdbae28828a25cfa6 412 Gene3D G3DSA:3.90.226.10 183 403 1.6E-65 T 22-04-2016 IPR029045 ClpP/crotonase-like domain L21SP4_RS04890 80e4da90e101481bdbae28828a25cfa6 412 SMART SM00245 173 364 9.0E-73 T 22-04-2016 IPR005151 Tail specific protease GO:0006508|GO:0008236 L21SP4_RS04890 80e4da90e101481bdbae28828a25cfa6 412 SMART SM00228 100 171 4.5E-15 T 22-04-2016 IPR001478 PDZ domain GO:0005515 L21SP4_RS04890 80e4da90e101481bdbae28828a25cfa6 412 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 53 366 2.5E-100 T 22-04-2016 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 L21SP4_RS04890 80e4da90e101481bdbae28828a25cfa6 412 SUPERFAMILY SSF50156 71 194 4.34E-23 T 22-04-2016 IPR001478 PDZ domain GO:0005515 L21SP4_RS04890 80e4da90e101481bdbae28828a25cfa6 412 SUPERFAMILY SSF52096 193 368 7.62E-74 T 22-04-2016 IPR029045 ClpP/crotonase-like domain L21SP4_RS04890 80e4da90e101481bdbae28828a25cfa6 412 SUPERFAMILY SSF52096 35 118 7.62E-74 T 22-04-2016 IPR029045 ClpP/crotonase-like domain L21SP4_RS04890 80e4da90e101481bdbae28828a25cfa6 412 Pfam PF13180 PDZ domain 101 179 3.9E-13 T 22-04-2016 IPR001478 PDZ domain GO:0005515 L21SP4_RS04890 80e4da90e101481bdbae28828a25cfa6 412 Gene3D G3DSA:2.30.42.10 106 182 5.2E-27 T 22-04-2016 IPR001478 PDZ domain GO:0005515 L21SP4_RS03350 e4aa9ce8e3b32c9a63c0ef556e34cef7 185 SUPERFAMILY SSF81593 28 125 8.24E-5 T 22-04-2016 L21SP4_RS03350 e4aa9ce8e3b32c9a63c0ef556e34cef7 185 Gene3D G3DSA:1.20.120.330 50 132 7.4E-5 T 22-04-2016 L21SP4_RS03475 b9e937cf07183ca9c51593f959297239 194 SUPERFAMILY SSF53383 8 193 4.34E-76 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase L21SP4_RS03475 b9e937cf07183ca9c51593f959297239 194 Pfam PF00464 Serine hydroxymethyltransferase 10 192 1.5E-78 T 22-04-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 L21SP4_RS03475 b9e937cf07183ca9c51593f959297239 194 Gene3D G3DSA:3.40.640.10 38 193 2.1E-54 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 L21SP4_RS03475 b9e937cf07183ca9c51593f959297239 194 PANTHER PTHR11680:SF9 1 194 2.9E-109 T 22-04-2016 L21SP4_RS03475 b9e937cf07183ca9c51593f959297239 194 PANTHER PTHR11680 1 194 2.9E-109 T 22-04-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 L21SP4_RS03330 f8379b9a5df69e9dc6c3666b03c0086a 894 SUPERFAMILY SSF52540 282 336 2.06E-14 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS03330 f8379b9a5df69e9dc6c3666b03c0086a 894 SUPERFAMILY SSF52540 134 191 2.06E-14 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS03330 f8379b9a5df69e9dc6c3666b03c0086a 894 SUPERFAMILY SSF52540 383 529 2.06E-14 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS03330 f8379b9a5df69e9dc6c3666b03c0086a 894 Gene3D G3DSA:3.40.91.30 771 848 1.5E-5 T 22-04-2016 IPR011578 Restriction endonuclease, FokI, C-terminal/endonuclease I, core GO:0003677|GO:0004536 L21SP4_RS03330 f8379b9a5df69e9dc6c3666b03c0086a 894 Gene3D G3DSA:3.40.50.300 398 530 1.4E-6 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS03330 f8379b9a5df69e9dc6c3666b03c0086a 894 Pfam PF04851 Type III restriction enzyme, res subunit 93 335 2.9E-20 T 22-04-2016 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 L21SP4_RS03330 f8379b9a5df69e9dc6c3666b03c0086a 894 Gene3D G3DSA:3.40.50.300 87 256 2.4E-7 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS03330 f8379b9a5df69e9dc6c3666b03c0086a 894 Gene3D G3DSA:3.40.50.300 289 336 2.4E-7 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS09685 85d2655954b7efd368cb4af883984ac4 476 Pfam PF00750 tRNA synthetases class I (R) 19 344 1.8E-98 T 22-04-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 L21SP4_RS09685 85d2655954b7efd368cb4af883984ac4 476 PRINTS PR01038 Arginyl-tRNA synthetase signature 22 37 1.3E-25 T 22-04-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 L21SP4_RS09685 85d2655954b7efd368cb4af883984ac4 476 PRINTS PR01038 Arginyl-tRNA synthetase signature 61 74 1.3E-25 T 22-04-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 L21SP4_RS09685 85d2655954b7efd368cb4af883984ac4 476 PRINTS PR01038 Arginyl-tRNA synthetase signature 205 226 1.3E-25 T 22-04-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 L21SP4_RS09685 85d2655954b7efd368cb4af883984ac4 476 PRINTS PR01038 Arginyl-tRNA synthetase signature 37 53 1.3E-25 T 22-04-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 L21SP4_RS09685 85d2655954b7efd368cb4af883984ac4 476 Gene3D G3DSA:1.10.730.10 352 476 5.7E-35 T 22-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 L21SP4_RS09685 85d2655954b7efd368cb4af883984ac4 476 PANTHER PTHR11956 18 476 1.1E-196 T 22-04-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 L21SP4_RS09685 85d2655954b7efd368cb4af883984ac4 476 SUPERFAMILY SSF52374 16 352 6.19E-89 T 22-04-2016 L21SP4_RS09685 85d2655954b7efd368cb4af883984ac4 476 PANTHER PTHR11956:SF1 18 476 1.1E-196 T 22-04-2016 L21SP4_RS09685 85d2655954b7efd368cb4af883984ac4 476 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 20 476 1.1E-136 T 22-04-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 L21SP4_RS09685 85d2655954b7efd368cb4af883984ac4 476 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 30 41 - T 22-04-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 L21SP4_RS09685 85d2655954b7efd368cb4af883984ac4 476 SUPERFAMILY SSF47323 353 476 5.75E-33 T 22-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 L21SP4_RS09685 85d2655954b7efd368cb4af883984ac4 476 SMART SM00836 358 476 1.7E-37 T 22-04-2016 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 L21SP4_RS09685 85d2655954b7efd368cb4af883984ac4 476 Gene3D G3DSA:3.40.50.620 18 350 2.2E-110 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP4_RS09685 85d2655954b7efd368cb4af883984ac4 476 Pfam PF05746 DALR anticodon binding domain 358 476 8.8E-33 T 22-04-2016 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 L21SP4_RS09090 1fc8cebceaec0db56e94ebbb11c3ba19 416 Pfam PF01926 50S ribosome-binding GTPase 12 125 2.0E-16 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 L21SP4_RS09090 1fc8cebceaec0db56e94ebbb11c3ba19 416 SUPERFAMILY SSF52540 11 168 4.29E-26 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS09090 1fc8cebceaec0db56e94ebbb11c3ba19 416 TIGRFAM TIGR03918 GTP_HydF: [FeFe] hydrogenase H-cluster maturation GTPase HydF 3 389 2.2E-154 T 22-04-2016 IPR023873 [FeFe]-hydrogenase H-cluster maturation GTPase HydF L21SP4_RS09090 1fc8cebceaec0db56e94ebbb11c3ba19 416 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 12 129 8.0E-15 T 22-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 L21SP4_RS09090 1fc8cebceaec0db56e94ebbb11c3ba19 416 PANTHER PTHR11649 4 232 1.3E-42 T 22-04-2016 L21SP4_RS09090 1fc8cebceaec0db56e94ebbb11c3ba19 416 PANTHER PTHR11649:SF59 4 232 1.3E-42 T 22-04-2016 L21SP4_RS09090 1fc8cebceaec0db56e94ebbb11c3ba19 416 Gene3D G3DSA:3.40.50.300 6 133 3.2E-24 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS12090 b10334c237995edd912da137c25f448f 344 Pfam PF01595 Domain of unknown function DUF21 14 197 1.3E-29 T 22-04-2016 IPR002550 Domain of unknown function DUF21 L21SP4_RS12090 b10334c237995edd912da137c25f448f 344 Pfam PF00571 CBS domain 284 333 0.0016 T 22-04-2016 IPR000644 CBS domain L21SP4_RS12090 b10334c237995edd912da137c25f448f 344 SUPERFAMILY SSF54631 205 334 1.2E-18 T 22-04-2016 L21SP4_RS12090 b10334c237995edd912da137c25f448f 344 PANTHER PTHR22777 1 334 7.4E-48 T 22-04-2016 L21SP4_RS12090 b10334c237995edd912da137c25f448f 344 Gene3D G3DSA:3.10.580.10 201 334 1.1E-13 T 22-04-2016 L21SP4_RS04590 f9c727f027a3a9b2fd97fc958ec3a5e3 768 SUPERFAMILY SSF51126 170 357 1.66E-7 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor L21SP4_RS04590 f9c727f027a3a9b2fd97fc958ec3a5e3 768 Pfam PF12951 Passenger-associated-transport-repeat 143 158 0.1 T 22-04-2016 IPR013425 Autotransporter-associated beta strand repeat L21SP4_RS04590 f9c727f027a3a9b2fd97fc958ec3a5e3 768 Pfam PF12951 Passenger-associated-transport-repeat 276 303 8.6E-10 T 22-04-2016 IPR013425 Autotransporter-associated beta strand repeat L21SP4_RS04590 f9c727f027a3a9b2fd97fc958ec3a5e3 768 Pfam PF12951 Passenger-associated-transport-repeat 373 403 0.049 T 22-04-2016 IPR013425 Autotransporter-associated beta strand repeat L21SP4_RS04590 f9c727f027a3a9b2fd97fc958ec3a5e3 768 SUPERFAMILY SSF51126 356 743 1.44E-7 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor L21SP4_RS04590 f9c727f027a3a9b2fd97fc958ec3a5e3 768 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 744 765 0.0017 T 22-04-2016 IPR013424 PEP-CTERM protein-sorting domain L21SP4_RS04590 f9c727f027a3a9b2fd97fc958ec3a5e3 768 Gene3D G3DSA:2.160.20.20 227 689 1.0E-4 T 22-04-2016 IPR012332 P22 tailspike C-terminal domain-like L21SP4_RS04590 f9c727f027a3a9b2fd97fc958ec3a5e3 768 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 273 303 2.4E-10 T 22-04-2016 IPR013425 Autotransporter-associated beta strand repeat L21SP4_RS10195 a52e9807e8953488e63637b40f989c84 356 Pfam PF09344 CT1975-like protein 4 341 4.8E-100 T 22-04-2016 IPR010148 CRISPR-associated protein, CT1975 L21SP4_RS10195 a52e9807e8953488e63637b40f989c84 356 TIGRFAM TIGR01869 casC_Cse4: CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI 4 330 3.7E-82 T 22-04-2016 IPR010148 CRISPR-associated protein, CT1975 L21SP4_RS02025 eb9510b3f4848e2a60ff7a7c7aaab8a9 824 PANTHER PTHR31151 104 556 1.1E-16 T 22-04-2016 L21SP4_RS02025 eb9510b3f4848e2a60ff7a7c7aaab8a9 824 SUPERFAMILY SSF48208 90 367 6.05E-16 T 22-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP4_RS02025 eb9510b3f4848e2a60ff7a7c7aaab8a9 824 Pfam PF07944 Beta-L-arabinofuranosidase, GH127 76 555 1.1E-42 T 22-04-2016 IPR012878 Beta-L-arabinofuranosidase, GH127 KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18 L21SP4_RS02025 eb9510b3f4848e2a60ff7a7c7aaab8a9 824 Gene3D G3DSA:1.50.10.10 119 243 3.7E-6 T 22-04-2016 IPR012341 Six-hairpin glycosidase GO:0003824 L21SP4_RS05615 c0cdb589358b4e6032292236b8fff7a0 233 TIGRFAM TIGR00214 lipB: lipoyl(octanoyl) transferase 29 209 4.5E-44 T 22-04-2016 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|UniPathway: UPA00538 L21SP4_RS05615 c0cdb589358b4e6032292236b8fff7a0 233 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 80 133 3.0E-10 T 22-04-2016 L21SP4_RS05615 c0cdb589358b4e6032292236b8fff7a0 233 Hamap MF_00013 Octanoyltransferase [lipB]. 2 213 31.505 T 22-04-2016 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|UniPathway: UPA00538 L21SP4_RS05615 c0cdb589358b4e6032292236b8fff7a0 233 Gene3D G3DSA:3.90.1550.10 5 210 2.5E-62 T 22-04-2016 L21SP4_RS05615 c0cdb589358b4e6032292236b8fff7a0 233 SUPERFAMILY SSF55681 3 212 2.49E-54 T 22-04-2016 L21SP4_RS05615 c0cdb589358b4e6032292236b8fff7a0 233 PANTHER PTHR10993 12 223 1.8E-69 T 22-04-2016 L21SP4_RS05615 c0cdb589358b4e6032292236b8fff7a0 233 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 76 91 - T 22-04-2016 IPR020605 Octanoyltransferase, conserved site GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|UniPathway: UPA00538 L21SP4_RS05615 c0cdb589358b4e6032292236b8fff7a0 233 PIRSF PIRSF016262 3 223 7.8E-55 T 22-04-2016 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|UniPathway: UPA00538 L21SP4_RS05615 c0cdb589358b4e6032292236b8fff7a0 233 Pfam PF03099 Biotin/lipoate A/B protein ligase family 63 162 2.8E-7 T 22-04-2016 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 L21SP4_RS09990 3d5237b9f0675b9845011bbdba9fe4a6 323 Pfam PF02674 Colicin V production protein 11 139 7.9E-11 T 22-04-2016 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 L21SP4_RS08075 b863496ee54500348f8f31d0630a7551 666 Gene3D G3DSA:2.40.170.20 173 666 1.7E-45 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 L21SP4_RS08075 b863496ee54500348f8f31d0630a7551 666 PANTHER PTHR32552 2 666 1.0E-38 T 22-04-2016 L21SP4_RS08075 b863496ee54500348f8f31d0630a7551 666 SUPERFAMILY SSF56935 53 666 4.71E-89 T 22-04-2016 L21SP4_RS08075 b863496ee54500348f8f31d0630a7551 666 Gene3D G3DSA:2.170.130.10 61 172 2.8E-32 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 L21SP4_RS08075 b863496ee54500348f8f31d0630a7551 666 Pfam PF07715 TonB-dependent Receptor Plug Domain 62 169 2.8E-21 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 L21SP4_RS08075 b863496ee54500348f8f31d0630a7551 666 Pfam PF00593 TonB dependent receptor 414 664 2.0E-16 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 L21SP4_RS07355 c939130301aa388aea2da010928d414d 202 Gene3D G3DSA:3.40.50.620 170 196 1.2E-9 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP4_RS07355 c939130301aa388aea2da010928d414d 202 Gene3D G3DSA:3.40.50.620 34 137 1.2E-9 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP4_RS07355 c939130301aa388aea2da010928d414d 202 PANTHER PTHR31285 27 197 2.1E-40 T 22-04-2016 L21SP4_RS07355 c939130301aa388aea2da010928d414d 202 SUPERFAMILY SSF52374 34 196 1.77E-9 T 22-04-2016 L21SP4_RS07355 c939130301aa388aea2da010928d414d 202 Pfam PF01467 Cytidylyltransferase-like 35 57 1.1E-4 T 22-04-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 L21SP4_RS05005 a6e3ff7dbb82eac56b4aa18b0a28dc6a 435 Gene3D G3DSA:3.40.50.300 2 217 1.8E-60 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS05005 a6e3ff7dbb82eac56b4aa18b0a28dc6a 435 PANTHER PTHR10434 152 430 3.1E-54 T 22-04-2016 L21SP4_RS05005 a6e3ff7dbb82eac56b4aa18b0a28dc6a 435 SUPERFAMILY SSF69593 228 431 3.92E-46 T 22-04-2016 L21SP4_RS05005 a6e3ff7dbb82eac56b4aa18b0a28dc6a 435 TIGRFAM TIGR00017 cmk: cytidylate kinase 2 215 1.1E-62 T 22-04-2016 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 L21SP4_RS05005 a6e3ff7dbb82eac56b4aa18b0a28dc6a 435 PANTHER PTHR10434:SF21 152 430 3.1E-54 T 22-04-2016 L21SP4_RS05005 a6e3ff7dbb82eac56b4aa18b0a28dc6a 435 Pfam PF02224 Cytidylate kinase 4 217 1.9E-61 T 22-04-2016 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 L21SP4_RS05005 a6e3ff7dbb82eac56b4aa18b0a28dc6a 435 SMART SM00563 264 377 5.7E-32 T 22-04-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 L21SP4_RS05005 a6e3ff7dbb82eac56b4aa18b0a28dc6a 435 Hamap MF_00238 Cytidylate kinase [cmk]. 2 220 28.154 T 22-04-2016 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 L21SP4_RS05005 a6e3ff7dbb82eac56b4aa18b0a28dc6a 435 Pfam PF01553 Acyltransferase 251 375 5.5E-23 T 22-04-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 L21SP4_RS05005 a6e3ff7dbb82eac56b4aa18b0a28dc6a 435 Gene3D G3DSA:3.40.1130.10 254 430 2.6E-33 T 22-04-2016 L21SP4_RS05005 a6e3ff7dbb82eac56b4aa18b0a28dc6a 435 SUPERFAMILY SSF52540 1 215 5.17E-32 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS08015 a81613cc61006448e0ef650411cab718 263 PANTHER PTHR12553:SF7 1 261 4.4E-60 T 22-04-2016 L21SP4_RS08015 a81613cc61006448e0ef650411cab718 263 SMART SM00849 34 231 1.3E-12 T 22-04-2016 IPR001279 Metallo-beta-lactamase L21SP4_RS08015 a81613cc61006448e0ef650411cab718 263 Pfam PF12706 Beta-lactamase superfamily domain 48 232 5.5E-39 T 22-04-2016 IPR001279 Metallo-beta-lactamase L21SP4_RS08015 a81613cc61006448e0ef650411cab718 263 SUPERFAMILY SSF56281 1 260 4.32E-48 T 22-04-2016 IPR001279 Metallo-beta-lactamase L21SP4_RS08015 a81613cc61006448e0ef650411cab718 263 PANTHER PTHR12553 1 261 4.4E-60 T 22-04-2016 L21SP4_RS08015 a81613cc61006448e0ef650411cab718 263 Gene3D G3DSA:3.60.15.10 1 260 1.1E-73 T 22-04-2016 IPR001279 Metallo-beta-lactamase L21SP4_RS01470 3cd5c392d554dab5395ff7e3294639b0 294 PANTHER PTHR30477 15 289 1.2E-62 T 22-04-2016 L21SP4_RS01470 3cd5c392d554dab5395ff7e3294639b0 294 SUPERFAMILY SSF53807 28 293 2.55E-71 T 22-04-2016 L21SP4_RS01470 3cd5c392d554dab5395ff7e3294639b0 294 Pfam PF01297 Zinc-uptake complex component A periplasmic 30 279 6.1E-53 T 22-04-2016 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 L21SP4_RS01470 3cd5c392d554dab5395ff7e3294639b0 294 PANTHER PTHR30477:SF1 15 289 1.2E-62 T 22-04-2016 L21SP4_RS01470 3cd5c392d554dab5395ff7e3294639b0 294 PRINTS PR00691 Adhesin B signature 27 48 4.2E-7 T 22-04-2016 IPR006129 Adhesin B GO:0007155 L21SP4_RS01470 3cd5c392d554dab5395ff7e3294639b0 294 PRINTS PR00691 Adhesin B signature 52 70 4.2E-7 T 22-04-2016 IPR006129 Adhesin B GO:0007155 L21SP4_RS01470 3cd5c392d554dab5395ff7e3294639b0 294 PRINTS PR00691 Adhesin B signature 135 154 4.2E-7 T 22-04-2016 IPR006129 Adhesin B GO:0007155 L21SP4_RS01470 3cd5c392d554dab5395ff7e3294639b0 294 PRINTS PR00691 Adhesin B signature 191 208 4.2E-7 T 22-04-2016 IPR006129 Adhesin B GO:0007155 L21SP4_RS01470 3cd5c392d554dab5395ff7e3294639b0 294 PRINTS PR00691 Adhesin B signature 71 90 4.2E-7 T 22-04-2016 IPR006129 Adhesin B GO:0007155 L21SP4_RS01470 3cd5c392d554dab5395ff7e3294639b0 294 Gene3D G3DSA:3.40.50.1980 28 192 5.8E-43 T 22-04-2016 L21SP4_RS01470 3cd5c392d554dab5395ff7e3294639b0 294 Gene3D G3DSA:3.40.50.1980 193 294 2.0E-25 T 22-04-2016 L21SP4_RS01470 3cd5c392d554dab5395ff7e3294639b0 294 PRINTS PR00690 Adhesin family signature 242 260 1.0E-6 T 22-04-2016 IPR006128 Adhesion lipoprotein GO:0007155 L21SP4_RS01470 3cd5c392d554dab5395ff7e3294639b0 294 PRINTS PR00690 Adhesin family signature 58 71 1.0E-6 T 22-04-2016 IPR006128 Adhesion lipoprotein GO:0007155 L21SP4_RS01470 3cd5c392d554dab5395ff7e3294639b0 294 PRINTS PR00690 Adhesin family signature 71 88 1.0E-6 T 22-04-2016 IPR006128 Adhesion lipoprotein GO:0007155 L21SP4_RS01470 3cd5c392d554dab5395ff7e3294639b0 294 PRINTS PR00690 Adhesin family signature 191 212 1.0E-6 T 22-04-2016 IPR006128 Adhesion lipoprotein GO:0007155 L21SP4_RS05620 50e11ca90f80b5110bd02df84d7b1655 128 Pfam PF01597 Glycine cleavage H-protein 8 126 1.9E-45 T 22-04-2016 IPR002930 Glycine cleavage system H-protein L21SP4_RS05620 50e11ca90f80b5110bd02df84d7b1655 128 PANTHER PTHR11715 1 128 1.5E-64 T 22-04-2016 IPR002930 Glycine cleavage system H-protein L21SP4_RS05620 50e11ca90f80b5110bd02df84d7b1655 128 SUPERFAMILY SSF51230 4 126 2.36E-44 T 22-04-2016 IPR011053 Single hybrid motif L21SP4_RS05620 50e11ca90f80b5110bd02df84d7b1655 128 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 48 77 - T 22-04-2016 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site L21SP4_RS05620 50e11ca90f80b5110bd02df84d7b1655 128 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 5 126 30.236 T 22-04-2016 IPR002930 Glycine cleavage system H-protein L21SP4_RS05620 50e11ca90f80b5110bd02df84d7b1655 128 Gene3D G3DSA:2.40.50.100 7 127 4.7E-49 T 22-04-2016 L21SP4_RS05620 50e11ca90f80b5110bd02df84d7b1655 128 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 4 127 3.9E-49 T 22-04-2016 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 L21SP4_RS03510 258b80ebc772a7bd00cb58cbee745ebb 203 Gene3D G3DSA:1.25.40.20 126 193 6.5E-22 T 22-04-2016 IPR020683 Ankyrin repeat-containing domain L21SP4_RS03510 258b80ebc772a7bd00cb58cbee745ebb 203 Pfam PF12796 Ankyrin repeats (3 copies) 42 106 2.2E-8 T 22-04-2016 IPR020683 Ankyrin repeat-containing domain L21SP4_RS03510 258b80ebc772a7bd00cb58cbee745ebb 203 Pfam PF12796 Ankyrin repeats (3 copies) 107 173 1.4E-11 T 22-04-2016 IPR020683 Ankyrin repeat-containing domain L21SP4_RS03510 258b80ebc772a7bd00cb58cbee745ebb 203 Gene3D G3DSA:1.25.40.20 43 125 5.8E-26 T 22-04-2016 IPR020683 Ankyrin repeat-containing domain L21SP4_RS03510 258b80ebc772a7bd00cb58cbee745ebb 203 PANTHER PTHR24188 42 190 8.4E-46 T 22-04-2016 L21SP4_RS03510 258b80ebc772a7bd00cb58cbee745ebb 203 SMART SM00248 75 104 1.1E-5 T 22-04-2016 IPR002110 Ankyrin repeat GO:0005515 L21SP4_RS03510 258b80ebc772a7bd00cb58cbee745ebb 203 SMART SM00248 108 137 0.0014 T 22-04-2016 IPR002110 Ankyrin repeat GO:0005515 L21SP4_RS03510 258b80ebc772a7bd00cb58cbee745ebb 203 SMART SM00248 142 171 0.0022 T 22-04-2016 IPR002110 Ankyrin repeat GO:0005515 L21SP4_RS03510 258b80ebc772a7bd00cb58cbee745ebb 203 PRINTS PR01415 Ankyrin repeat signature 124 138 1.66E-6 T 22-04-2016 IPR002110 Ankyrin repeat GO:0005515 L21SP4_RS03510 258b80ebc772a7bd00cb58cbee745ebb 203 PRINTS PR01415 Ankyrin repeat signature 76 91 1.66E-6 T 22-04-2016 IPR002110 Ankyrin repeat GO:0005515 L21SP4_RS03510 258b80ebc772a7bd00cb58cbee745ebb 203 SUPERFAMILY SSF48403 42 193 2.21E-41 T 22-04-2016 IPR020683 Ankyrin repeat-containing domain L21SP4_RS04940 05fbc59ec9bd72485dd1ef0c2340f860 295 Pfam PF01882 Protein of unknown function DUF58 36 121 3.1E-21 T 22-04-2016 IPR002881 Domain of unknown function DUF58 L21SP4_RS04940 05fbc59ec9bd72485dd1ef0c2340f860 295 SUPERFAMILY SSF53300 76 195 3.06E-13 T 22-04-2016 IPR002035 von Willebrand factor, type A L21SP4_RS04940 05fbc59ec9bd72485dd1ef0c2340f860 295 PANTHER PTHR33608 2 292 1.8E-62 T 22-04-2016 L21SP4_RS04940 05fbc59ec9bd72485dd1ef0c2340f860 295 Gene3D G3DSA:3.40.50.410 75 170 3.0E-6 T 22-04-2016 IPR002035 von Willebrand factor, type A L21SP4_RS04940 05fbc59ec9bd72485dd1ef0c2340f860 295 PANTHER PTHR33608:SF5 2 292 1.8E-62 T 22-04-2016 L21SP4_RS06010 8d3025b74f2be0eb9f844d4bcb9e0d5f 584 PANTHER PTHR10342:SF199 1 367 2.5E-104 T 22-04-2016 L21SP4_RS06010 8d3025b74f2be0eb9f844d4bcb9e0d5f 584 PANTHER PTHR10342:SF199 389 473 2.5E-104 T 22-04-2016 L21SP4_RS06010 8d3025b74f2be0eb9f844d4bcb9e0d5f 584 Gene3D G3DSA:3.40.720.10 25 351 2.0E-86 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS06010 8d3025b74f2be0eb9f844d4bcb9e0d5f 584 Gene3D G3DSA:3.30.1120.10 380 454 4.8E-10 T 22-04-2016 L21SP4_RS06010 8d3025b74f2be0eb9f844d4bcb9e0d5f 584 PANTHER PTHR10342 1 367 2.5E-104 T 22-04-2016 L21SP4_RS06010 8d3025b74f2be0eb9f844d4bcb9e0d5f 584 PANTHER PTHR10342 389 473 2.5E-104 T 22-04-2016 L21SP4_RS06010 8d3025b74f2be0eb9f844d4bcb9e0d5f 584 Pfam PF00884 Sulfatase 28 327 6.9E-61 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS06010 8d3025b74f2be0eb9f844d4bcb9e0d5f 584 SUPERFAMILY SSF53649 26 441 1.0E-105 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS04020 3804aced1ec9213fcb09627dacf2d83f 116 PIRSF PIRSF006246 1 115 1.4E-45 T 22-04-2016 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155|UniPathway: UPA00028 L21SP4_RS04020 3804aced1ec9213fcb09627dacf2d83f 116 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 116 60.017 T 22-04-2016 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155|UniPathway: UPA00028 L21SP4_RS04020 3804aced1ec9213fcb09627dacf2d83f 116 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 5 113 6.0E-26 T 22-04-2016 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155|UniPathway: UPA00028 L21SP4_RS04020 3804aced1ec9213fcb09627dacf2d83f 116 PANTHER PTHR21012 2 115 3.6E-57 T 22-04-2016 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155|UniPathway: UPA00028 L21SP4_RS04020 3804aced1ec9213fcb09627dacf2d83f 116 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 1 113 1.9E-38 T 22-04-2016 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155|UniPathway: UPA00028 L21SP4_RS04020 3804aced1ec9213fcb09627dacf2d83f 116 Pfam PF02261 Aspartate decarboxylase 1 114 9.2E-45 T 22-04-2016 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155|UniPathway: UPA00028 L21SP4_RS04020 3804aced1ec9213fcb09627dacf2d83f 116 PANTHER PTHR21012:SF0 2 115 3.6E-57 T 22-04-2016 L21SP4_RS04020 3804aced1ec9213fcb09627dacf2d83f 116 Gene3D G3DSA:2.40.40.20 1 114 3.6E-46 T 22-04-2016 L21SP4_RS04020 3804aced1ec9213fcb09627dacf2d83f 116 SUPERFAMILY SSF50692 1 114 8.95E-43 T 22-04-2016 IPR009010 Aspartate decarboxylase-like domain L21SP4_RS05205 84a139ecb5bdf3e900213beca108d641 184 PANTHER PTHR11019:SF4 1 180 4.8E-53 T 22-04-2016 L21SP4_RS05205 84a139ecb5bdf3e900213beca108d641 184 TIGRFAM TIGR01383 not_thiJ: DJ-1 family protein 3 175 1.6E-51 T 22-04-2016 IPR006287 DJ-1 L21SP4_RS05205 84a139ecb5bdf3e900213beca108d641 184 PANTHER PTHR11019 1 180 4.8E-53 T 22-04-2016 L21SP4_RS05205 84a139ecb5bdf3e900213beca108d641 184 Gene3D G3DSA:3.40.50.880 1 180 4.5E-59 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like L21SP4_RS05205 84a139ecb5bdf3e900213beca108d641 184 SUPERFAMILY SSF52317 1 179 1.26E-54 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like L21SP4_RS05205 84a139ecb5bdf3e900213beca108d641 184 Pfam PF01965 DJ-1/PfpI family 3 163 4.0E-48 T 22-04-2016 IPR002818 DJ-1/PfpI L21SP4_RS05890 5c7b37335c89ec143c42313f1cff2f82 276 Pfam PF00685 Sulfotransferase domain 37 225 2.7E-12 T 22-04-2016 IPR000863 Sulfotransferase domain GO:0008146 L21SP4_RS05890 5c7b37335c89ec143c42313f1cff2f82 276 Gene3D G3DSA:3.40.50.300 31 262 1.1E-20 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS05890 5c7b37335c89ec143c42313f1cff2f82 276 SUPERFAMILY SSF52540 34 263 9.11E-22 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS10925 b0692b054fdf6289d89324274265b195 258 SUPERFAMILY SSF53335 1 205 9.88E-30 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS10925 b0692b054fdf6289d89324274265b195 258 PANTHER PTHR10108 1 137 6.0E-17 T 22-04-2016 L21SP4_RS10925 b0692b054fdf6289d89324274265b195 258 Gene3D G3DSA:3.40.50.150 24 250 3.6E-29 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS10925 b0692b054fdf6289d89324274265b195 258 Pfam PF13649 Methyltransferase domain 43 134 2.1E-13 T 22-04-2016 L21SP4_RS02525 6ebdb32011ec40a65d54813e0d783357 406 SUPERFAMILY SSF48019 243 369 1.02E-13 T 22-04-2016 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: REACT_152|Reactome: REACT_1538|Reactome: REACT_216|Reactome: REACT_22172|Reactome: REACT_383 L21SP4_RS02525 6ebdb32011ec40a65d54813e0d783357 406 SMART SM00382 37 179 7.6E-11 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS02525 6ebdb32011ec40a65d54813e0d783357 406 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 41 59 8.2E-6 T 22-04-2016 IPR001270 ClpA/B family GO:0005524 L21SP4_RS02525 6ebdb32011ec40a65d54813e0d783357 406 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 124 142 8.2E-6 T 22-04-2016 IPR001270 ClpA/B family GO:0005524 L21SP4_RS02525 6ebdb32011ec40a65d54813e0d783357 406 PANTHER PTHR11669 1 357 6.8E-170 T 22-04-2016 L21SP4_RS02525 6ebdb32011ec40a65d54813e0d783357 406 Pfam PF13177 DNA polymerase III, delta subunit 20 178 4.0E-43 T 22-04-2016 L21SP4_RS02525 6ebdb32011ec40a65d54813e0d783357 406 Gene3D G3DSA:1.10.8.60 167 242 5.4E-29 T 22-04-2016 L21SP4_RS02525 6ebdb32011ec40a65d54813e0d783357 406 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 233 374 1.3E-16 T 22-04-2016 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 L21SP4_RS02525 6ebdb32011ec40a65d54813e0d783357 406 Gene3D G3DSA:3.40.50.300 15 166 1.8E-70 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS02525 6ebdb32011ec40a65d54813e0d783357 406 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 3 357 7.7E-137 T 22-04-2016 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 L21SP4_RS02525 6ebdb32011ec40a65d54813e0d783357 406 SUPERFAMILY SSF52540 34 220 1.07E-56 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS02525 6ebdb32011ec40a65d54813e0d783357 406 Gene3D G3DSA:1.20.272.10 243 357 8.9E-12 T 22-04-2016 L21SP4_RS02525 6ebdb32011ec40a65d54813e0d783357 406 PANTHER PTHR11669:SF0 1 357 6.8E-170 T 22-04-2016 L21SP4_RS11135 f55cb10ae8180ae4cb902e26e3c052ef 283 Pfam PF00535 Glycosyl transferase family 2 4 142 7.0E-17 T 22-04-2016 IPR001173 Glycosyltransferase 2-like L21SP4_RS11135 f55cb10ae8180ae4cb902e26e3c052ef 283 PANTHER PTHR22916 1 189 2.1E-41 T 22-04-2016 L21SP4_RS11135 f55cb10ae8180ae4cb902e26e3c052ef 283 PANTHER PTHR22916:SF4 1 189 2.1E-41 T 22-04-2016 L21SP4_RS11135 f55cb10ae8180ae4cb902e26e3c052ef 283 Gene3D G3DSA:3.90.550.10 1 206 1.2E-35 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases L21SP4_RS11135 f55cb10ae8180ae4cb902e26e3c052ef 283 SUPERFAMILY SSF53448 1 205 2.57E-40 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases L21SP4_RS07960 f52fb7c2b23947ad25c41780308585d6 156 PANTHER PTHR33202:SF7 8 146 1.7E-31 T 22-04-2016 L21SP4_RS07960 f52fb7c2b23947ad25c41780308585d6 156 PANTHER PTHR33202 8 146 1.7E-31 T 22-04-2016 L21SP4_RS07960 f52fb7c2b23947ad25c41780308585d6 156 SUPERFAMILY SSF46785 14 118 5.75E-29 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS07960 f52fb7c2b23947ad25c41780308585d6 156 Gene3D G3DSA:1.10.10.10 13 91 3.4E-23 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS07960 f52fb7c2b23947ad25c41780308585d6 156 Pfam PF01475 Ferric uptake regulator family 22 113 4.3E-24 T 22-04-2016 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 L21SP4_RS07500 03ff2f7a9c26743a591d85bd02316b1e 770 Pfam PF12161 HsdM N-terminal domain 9 149 5.6E-19 T 22-04-2016 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain L21SP4_RS07500 03ff2f7a9c26743a591d85bd02316b1e 770 Gene3D G3DSA:3.40.50.150 200 460 8.0E-26 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS07500 03ff2f7a9c26743a591d85bd02316b1e 770 Pfam PF02384 N-6 DNA Methylase 175 490 6.2E-50 T 22-04-2016 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 L21SP4_RS07500 03ff2f7a9c26743a591d85bd02316b1e 770 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 310 316 - T 22-04-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 L21SP4_RS07500 03ff2f7a9c26743a591d85bd02316b1e 770 SUPERFAMILY SSF53335 82 558 4.07E-107 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS07500 03ff2f7a9c26743a591d85bd02316b1e 770 SUPERFAMILY SSF53335 9 47 4.07E-107 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS07500 03ff2f7a9c26743a591d85bd02316b1e 770 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 307 319 3.7E-11 T 22-04-2016 L21SP4_RS07500 03ff2f7a9c26743a591d85bd02316b1e 770 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 229 243 3.7E-11 T 22-04-2016 L21SP4_RS07500 03ff2f7a9c26743a591d85bd02316b1e 770 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 198 214 3.7E-11 T 22-04-2016 L21SP4_RS07500 03ff2f7a9c26743a591d85bd02316b1e 770 PANTHER PTHR30195:SF10 109 763 1.4E-214 T 22-04-2016 L21SP4_RS07500 03ff2f7a9c26743a591d85bd02316b1e 770 PANTHER PTHR30195 109 763 1.4E-214 T 22-04-2016 L21SP4_RS11395 47e4f1baf1eaa9a91a9cb3953b054006 498 Pfam PF01943 Polysaccharide biosynthesis protein 9 288 1.0E-24 T 22-04-2016 IPR002797 Polysaccharide biosynthesis protein GO:0016020 L21SP4_RS11395 47e4f1baf1eaa9a91a9cb3953b054006 498 PANTHER PTHR30250:SF0 1 481 1.7E-39 T 22-04-2016 L21SP4_RS11395 47e4f1baf1eaa9a91a9cb3953b054006 498 PANTHER PTHR30250 1 481 1.7E-39 T 22-04-2016 L21SP4_RS11395 47e4f1baf1eaa9a91a9cb3953b054006 498 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 345 480 1.9E-12 T 22-04-2016 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain L21SP4_RS03220 a72d9dc56a408a2332e5ae2e7794c12c 447 Gene3D G3DSA:3.40.50.10140 298 406 1.2E-6 T 22-04-2016 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 L21SP4_RS03220 a72d9dc56a408a2332e5ae2e7794c12c 447 Pfam PF13676 TIR domain 298 400 1.7E-15 T 22-04-2016 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 L21SP4_RS03220 a72d9dc56a408a2332e5ae2e7794c12c 447 SUPERFAMILY SSF52200 298 413 6.15E-15 T 22-04-2016 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 L21SP4_RS09610 0cdb758227fe132851eceaaf132a1866 125 Pfam PF01850 PIN domain 1 106 5.9E-12 T 22-04-2016 IPR002716 PIN domain L21SP4_RS09610 0cdb758227fe132851eceaaf132a1866 125 Gene3D G3DSA:3.40.50.1010 2 124 6.1E-22 T 22-04-2016 IPR029060 PIN domain-like L21SP4_RS09610 0cdb758227fe132851eceaaf132a1866 125 PANTHER PTHR33653 1 125 6.6E-24 T 22-04-2016 L21SP4_RS09610 0cdb758227fe132851eceaaf132a1866 125 PANTHER PTHR33653:SF2 1 125 6.6E-24 T 22-04-2016 L21SP4_RS09610 0cdb758227fe132851eceaaf132a1866 125 SUPERFAMILY SSF88723 2 123 1.71E-24 T 22-04-2016 IPR029060 PIN domain-like L21SP4_RS05490 c3dc5e0c451e178d0817e73ec40f4719 430 ProSitePatterns PS01012 Folylpolyglutamate synthase signature 2. 131 146 - T 22-04-2016 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 L21SP4_RS05490 c3dc5e0c451e178d0817e73ec40f4719 430 PANTHER PTHR11136 1 411 1.7E-109 T 22-04-2016 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|UniPathway: UPA00850 L21SP4_RS05490 c3dc5e0c451e178d0817e73ec40f4719 430 TIGRFAM TIGR01499 folC: bifunctional protein FolC 14 416 4.1E-101 T 22-04-2016 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|UniPathway: UPA00850 L21SP4_RS05490 c3dc5e0c451e178d0817e73ec40f4719 430 PIRSF PIRSF001563 1 420 3.0E-111 T 22-04-2016 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|UniPathway: UPA00850 L21SP4_RS05490 c3dc5e0c451e178d0817e73ec40f4719 430 SUPERFAMILY SSF53244 287 415 1.92E-18 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 L21SP4_RS05490 c3dc5e0c451e178d0817e73ec40f4719 430 PANTHER PTHR11136:SF0 1 411 1.7E-109 T 22-04-2016 L21SP4_RS05490 c3dc5e0c451e178d0817e73ec40f4719 430 SUPERFAMILY SSF53623 7 283 1.83E-82 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 L21SP4_RS05490 c3dc5e0c451e178d0817e73ec40f4719 430 Pfam PF08245 Mur ligase middle domain 35 261 7.3E-9 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 L21SP4_RS05490 c3dc5e0c451e178d0817e73ec40f4719 430 Gene3D G3DSA:3.40.1190.10 3 285 4.2E-86 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 L21SP4_RS05490 c3dc5e0c451e178d0817e73ec40f4719 430 Gene3D G3DSA:3.90.190.20 287 414 7.7E-22 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 L21SP4_RS10470 800d428e0d6fa64f1af2f96a176f1478 575 Gene3D G3DSA:4.10.1080.10 510 556 3.7E-4 T 22-04-2016 IPR028974 TSP type-3 repeat GO:0005509 L21SP4_RS10470 800d428e0d6fa64f1af2f96a176f1478 575 SUPERFAMILY SSF52266 300 509 7.97E-25 T 22-04-2016 IPR013830 SGNH hydrolase-type esterase domain L21SP4_RS10470 800d428e0d6fa64f1af2f96a176f1478 575 SUPERFAMILY SSF52266 228 265 7.97E-25 T 22-04-2016 IPR013830 SGNH hydrolase-type esterase domain L21SP4_RS10470 800d428e0d6fa64f1af2f96a176f1478 575 Pfam PF03629 Carbohydrate esterase, sialic acid-specific acetylesterase 380 471 2.2E-7 T 22-04-2016 IPR005181 Sialate O-acetylesterase domain L21SP4_RS06385 67b303f0eb74e2eeed6cc4914270974c 173 PIRSF PIRSF000216 1 171 2.9E-51 T 22-04-2016 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 L21SP4_RS06385 67b303f0eb74e2eeed6cc4914270974c 173 Gene3D G3DSA:3.40.30.10 77 156 9.3E-11 T 22-04-2016 IPR012336 Thioredoxin-like fold L21SP4_RS06385 67b303f0eb74e2eeed6cc4914270974c 173 SUPERFAMILY SSF52833 7 159 1.12E-48 T 22-04-2016 IPR012336 Thioredoxin-like fold L21SP4_RS06385 67b303f0eb74e2eeed6cc4914270974c 173 ProSitePatterns PS01099 Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. 114 132 - T 22-04-2016 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 L21SP4_RS06385 67b303f0eb74e2eeed6cc4914270974c 173 PANTHER PTHR10371 7 158 1.5E-50 T 22-04-2016 L21SP4_RS06385 67b303f0eb74e2eeed6cc4914270974c 173 TIGRFAM TIGR01958 nuoE_fam: NADH-quinone oxidoreductase, E subunit 13 155 2.5E-44 T 22-04-2016 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 L21SP4_RS06385 67b303f0eb74e2eeed6cc4914270974c 173 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 13 156 5.8E-49 T 22-04-2016 L21SP4_RS00065 83d2fcf20404e32e3d49464e17a8e4d0 315 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 130 141 - T 22-04-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 L21SP4_RS00065 83d2fcf20404e32e3d49464e17a8e4d0 315 Gene3D G3DSA:3.20.20.70 1 307 3.6E-90 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP4_RS00065 83d2fcf20404e32e3d49464e17a8e4d0 315 PIRSF PIRSF001359 1 307 1.7E-79 T 22-04-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 L21SP4_RS00065 83d2fcf20404e32e3d49464e17a8e4d0 315 SUPERFAMILY SSF51569 1 306 1.61E-85 T 22-04-2016 L21SP4_RS00065 83d2fcf20404e32e3d49464e17a8e4d0 315 PANTHER PTHR30304 2 280 3.9E-82 T 22-04-2016 L21SP4_RS00065 83d2fcf20404e32e3d49464e17a8e4d0 315 Pfam PF01116 Fructose-bisphosphate aldolase class-II 4 306 1.5E-82 T 22-04-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 L21SP4_RS00065 83d2fcf20404e32e3d49464e17a8e4d0 315 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 304 1.7E-72 T 22-04-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 L21SP4_RS10440 6dc44c979ba5a74615da9959f6bf64f6 422 PANTHER PTHR12526 3 146 1.7E-15 T 22-04-2016 L21SP4_RS10440 6dc44c979ba5a74615da9959f6bf64f6 422 PANTHER PTHR12526 162 417 1.7E-15 T 22-04-2016 L21SP4_RS10440 6dc44c979ba5a74615da9959f6bf64f6 422 SUPERFAMILY SSF53756 4 403 2.09E-28 T 22-04-2016 L21SP4_RS10440 6dc44c979ba5a74615da9959f6bf64f6 422 Gene3D G3DSA:3.40.50.2000 211 352 2.3E-8 T 22-04-2016 L21SP4_RS10440 6dc44c979ba5a74615da9959f6bf64f6 422 Pfam PF00534 Glycosyl transferases group 1 213 390 1.0E-10 T 22-04-2016 IPR001296 Glycosyl transferase, family 1 L21SP4_RS08940 7987dd4024dd80511885397b12b602f2 497 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 85 202 5.6E-7 T 22-04-2016 L21SP4_RS01410 3f522ae1d1bbc7999a649e5a0b7a763b 241 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 2 24 1.5E-8 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site L21SP4_RS01410 3f522ae1d1bbc7999a649e5a0b7a763b 241 Pfam PF13633 Prokaryotic N-terminal methylation site 3 26 1.2E-7 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site L21SP4_RS01410 3f522ae1d1bbc7999a649e5a0b7a763b 241 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 3 23 - T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site L21SP4_RS03525 a3183fe49cc12fbbbd04a4b7fc54281e 204 SUPERFAMILY SSF53098 9 202 8.35E-19 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS03525 a3183fe49cc12fbbbd04a4b7fc54281e 204 Gene3D G3DSA:3.30.420.10 10 202 1.9E-28 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS03525 a3183fe49cc12fbbbd04a4b7fc54281e 204 SMART SM00479 10 204 0.0075 T 22-04-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III L21SP4_RS03525 a3183fe49cc12fbbbd04a4b7fc54281e 204 Pfam PF00929 Exonuclease 12 194 1.0E-9 T 22-04-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III L21SP4_RS01700 8c024af3e4e860616053889c0ac1953d 94 SUPERFAMILY SSF47729 6 93 1.47E-22 T 22-04-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 L21SP4_RS01700 8c024af3e4e860616053889c0ac1953d 94 Pfam PF00216 Bacterial DNA-binding protein 6 93 3.6E-24 T 22-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 L21SP4_RS01700 8c024af3e4e860616053889c0ac1953d 94 SMART SM00411 5 94 7.2E-20 T 22-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 L21SP4_RS01700 8c024af3e4e860616053889c0ac1953d 94 PRINTS PR01727 Prokaryotic integration host factor signature 62 75 8.4E-8 T 22-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 L21SP4_RS01700 8c024af3e4e860616053889c0ac1953d 94 PRINTS PR01727 Prokaryotic integration host factor signature 78 92 8.4E-8 T 22-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 L21SP4_RS01700 8c024af3e4e860616053889c0ac1953d 94 PRINTS PR01727 Prokaryotic integration host factor signature 44 59 8.4E-8 T 22-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 L21SP4_RS01700 8c024af3e4e860616053889c0ac1953d 94 PANTHER PTHR33175 6 93 4.5E-25 T 22-04-2016 L21SP4_RS01700 8c024af3e4e860616053889c0ac1953d 94 Gene3D G3DSA:4.10.520.10 6 93 4.9E-25 T 22-04-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 L21SP4_RS01920 d5d9e1b5eb997018d47b51b6740803b8 195 Gene3D G3DSA:3.40.50.10490 21 184 2.9E-30 T 22-04-2016 L21SP4_RS01920 d5d9e1b5eb997018d47b51b6740803b8 195 SUPERFAMILY SSF53697 24 189 2.83E-34 T 22-04-2016 L21SP4_RS01920 d5d9e1b5eb997018d47b51b6740803b8 195 Pfam PF01380 SIS domain 34 164 2.0E-19 T 22-04-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 Reactome: REACT_17015 L21SP4_RS01920 d5d9e1b5eb997018d47b51b6740803b8 195 PANTHER PTHR30514:SF1 29 169 2.6E-16 T 22-04-2016 L21SP4_RS01920 d5d9e1b5eb997018d47b51b6740803b8 195 PANTHER PTHR30514 29 169 2.6E-16 T 22-04-2016 L21SP4_RS08955 88e70bd8e4f7b231592c8318119d7426 318 Pfam PF14100 Methane oxygenase PmoA 48 308 2.1E-60 T 22-04-2016 IPR029475 Methane oxygenase PmoA L21SP4_RS03280 505fc555845718dce720a4747700e00e 320 Pfam PF02592 Putative vitamin uptake transporter 22 173 4.8E-7 T 22-04-2016 IPR003744 Protein of unknown function DUF165 L21SP4_RS05605 cfbfa11f145c5f276b4aebee14b67843 418 SUPERFAMILY SSF51556 48 339 2.55E-87 T 22-04-2016 IPR032466 Metal-dependent hydrolase L21SP4_RS05605 cfbfa11f145c5f276b4aebee14b67843 418 PANTHER PTHR11271 16 416 6.0E-137 T 22-04-2016 L21SP4_RS05605 cfbfa11f145c5f276b4aebee14b67843 418 Gene3D G3DSA:2.30.40.10 13 59 1.1E-6 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 L21SP4_RS05605 cfbfa11f145c5f276b4aebee14b67843 418 Pfam PF01979 Amidohydrolase family 46 390 1.2E-58 T 22-04-2016 IPR006680 Amidohydrolase-related GO:0016787 L21SP4_RS05605 cfbfa11f145c5f276b4aebee14b67843 418 SUPERFAMILY SSF51338 4 48 9.21E-20 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 L21SP4_RS05605 cfbfa11f145c5f276b4aebee14b67843 418 SUPERFAMILY SSF51338 342 414 9.21E-20 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 L21SP4_RS05605 cfbfa11f145c5f276b4aebee14b67843 418 Gene3D G3DSA:3.20.20.140 60 361 3.1E-90 T 22-04-2016 L21SP4_RS05605 cfbfa11f145c5f276b4aebee14b67843 418 PANTHER PTHR11271:SF7 16 416 6.0E-137 T 22-04-2016 L21SP4_RS08805 c16e99192c3bb37ddb055856e77b58d4 247 SUPERFAMILY SSF53335 10 170 2.24E-27 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS08805 c16e99192c3bb37ddb055856e77b58d4 247 SUPERFAMILY SSF53335 197 227 2.24E-27 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS08805 c16e99192c3bb37ddb055856e77b58d4 247 Pfam PF13489 Methyltransferase domain 40 217 5.6E-17 T 22-04-2016 L21SP4_RS08805 c16e99192c3bb37ddb055856e77b58d4 247 PANTHER PTHR10108 3 229 4.5E-12 T 22-04-2016 L21SP4_RS08805 c16e99192c3bb37ddb055856e77b58d4 247 Gene3D G3DSA:3.40.50.150 40 225 3.4E-25 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS06360 4e739c74cfa158dce1f8c363cd48c2bc 86 Pfam PF01381 Helix-turn-helix 20 72 5.3E-15 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 L21SP4_RS06360 4e739c74cfa158dce1f8c363cd48c2bc 86 SMART SM00530 18 73 1.2E-12 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 L21SP4_RS06360 4e739c74cfa158dce1f8c363cd48c2bc 86 SUPERFAMILY SSF47413 12 75 5.91E-15 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 L21SP4_RS06360 4e739c74cfa158dce1f8c363cd48c2bc 86 Gene3D G3DSA:1.10.260.40 11 74 1.1E-14 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 L21SP4_RS11610 296ef21ddfa6e3c7e080d4494abbe054 376 Pfam PF00633 Helix-hairpin-helix motif 111 137 7.4E-6 T 22-04-2016 IPR000445 Helix-hairpin-helix motif GO:0003677 L21SP4_RS11610 296ef21ddfa6e3c7e080d4494abbe054 376 ProSitePatterns PS00893 Nudix box signature. 269 290 - T 22-04-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 L21SP4_RS11610 296ef21ddfa6e3c7e080d4494abbe054 376 SUPERFAMILY SSF55811 224 358 6.23E-38 T 22-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 L21SP4_RS11610 296ef21ddfa6e3c7e080d4494abbe054 376 Gene3D G3DSA:1.10.340.30 31 132 7.7E-43 T 22-04-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 L21SP4_RS11610 296ef21ddfa6e3c7e080d4494abbe054 376 PRINTS PR00502 NUDIX hydrolase family signature 264 278 2.403879E-7 T 22-04-2016 IPR020476 NUDIX hydrolase L21SP4_RS11610 296ef21ddfa6e3c7e080d4494abbe054 376 PRINTS PR00502 NUDIX hydrolase family signature 278 293 2.403879E-7 T 22-04-2016 IPR020476 NUDIX hydrolase L21SP4_RS11610 296ef21ddfa6e3c7e080d4494abbe054 376 Pfam PF14815 NUDIX domain 239 356 3.2E-20 T 22-04-2016 IPR029119 MutY, C-terminal L21SP4_RS11610 296ef21ddfa6e3c7e080d4494abbe054 376 Gene3D G3DSA:1.10.1670.10 133 227 8.6E-35 T 22-04-2016 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal L21SP4_RS11610 296ef21ddfa6e3c7e080d4494abbe054 376 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 45 172 3.6E-16 T 22-04-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: REACT_216 L21SP4_RS11610 296ef21ddfa6e3c7e080d4494abbe054 376 SUPERFAMILY SSF48150 15 226 2.98E-69 T 22-04-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 L21SP4_RS11610 296ef21ddfa6e3c7e080d4494abbe054 376 SMART SM00478 49 194 1.2E-41 T 22-04-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: REACT_216 L21SP4_RS11610 296ef21ddfa6e3c7e080d4494abbe054 376 PANTHER PTHR10359 15 359 1.5E-89 T 22-04-2016 L21SP4_RS11610 296ef21ddfa6e3c7e080d4494abbe054 376 PANTHER PTHR10359:SF1 15 359 1.5E-89 T 22-04-2016 L21SP4_RS11610 296ef21ddfa6e3c7e080d4494abbe054 376 ProSitePatterns PS01155 Endonuclease III family signature. 112 141 - T 22-04-2016 IPR004036 Endonuclease III-like, conserved site-2 Reactome: REACT_216 L21SP4_RS11610 296ef21ddfa6e3c7e080d4494abbe054 376 SMART SM00525 195 215 0.0025 T 22-04-2016 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: REACT_216 L21SP4_RS11610 296ef21ddfa6e3c7e080d4494abbe054 376 TIGRFAM TIGR01084 mutY: A/G-specific adenine glycosylase 18 268 1.5E-92 T 22-04-2016 IPR005760 A/G-specific adenine glycosylase MutY GO:0006284|GO:0019104 L21SP4_RS11610 296ef21ddfa6e3c7e080d4494abbe054 376 Gene3D G3DSA:3.90.79.10 234 359 3.1E-32 T 22-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 L21SP4_RS01395 138617444aeff47fdce0de45e18eaf76 187 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 7 172 1.0E-39 T 22-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 L21SP4_RS01395 138617444aeff47fdce0de45e18eaf76 187 Pfam PF01327 Polypeptide deformylase 4 166 8.7E-47 T 22-04-2016 IPR023635 Peptide deformylase L21SP4_RS01395 138617444aeff47fdce0de45e18eaf76 187 Hamap MF_00163 Peptide deformylase [def]. 1 176 27.944 T 22-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 L21SP4_RS01395 138617444aeff47fdce0de45e18eaf76 187 PANTHER PTHR10458 1 178 2.0E-58 T 22-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 L21SP4_RS01395 138617444aeff47fdce0de45e18eaf76 187 Gene3D G3DSA:3.90.45.10 5 180 1.6E-56 T 22-04-2016 IPR023635 Peptide deformylase L21SP4_RS01395 138617444aeff47fdce0de45e18eaf76 187 PIRSF PIRSF004749 1 185 3.7E-47 T 22-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 L21SP4_RS01395 138617444aeff47fdce0de45e18eaf76 187 PRINTS PR01576 Peptide deformylase signature 32 61 1.4E-31 T 22-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 L21SP4_RS01395 138617444aeff47fdce0de45e18eaf76 187 PRINTS PR01576 Peptide deformylase signature 103 114 1.4E-31 T 22-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 L21SP4_RS01395 138617444aeff47fdce0de45e18eaf76 187 PRINTS PR01576 Peptide deformylase signature 115 133 1.4E-31 T 22-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 L21SP4_RS01395 138617444aeff47fdce0de45e18eaf76 187 PRINTS PR01576 Peptide deformylase signature 134 163 1.4E-31 T 22-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 L21SP4_RS01395 138617444aeff47fdce0de45e18eaf76 187 SUPERFAMILY SSF56420 1 176 3.27E-52 T 22-04-2016 IPR023635 Peptide deformylase L21SP4_RS03715 7503e3184f1afec6de1e46be6a0b099e 615 PANTHER PTHR10937:SF0 1 615 1.7E-293 T 22-04-2016 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: REACT_17015 L21SP4_RS03715 7503e3184f1afec6de1e46be6a0b099e 615 Pfam PF01380 SIS domain 298 420 1.6E-28 T 22-04-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 Reactome: REACT_17015 L21SP4_RS03715 7503e3184f1afec6de1e46be6a0b099e 615 Pfam PF01380 SIS domain 473 595 7.1E-17 T 22-04-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 Reactome: REACT_17015 L21SP4_RS03715 7503e3184f1afec6de1e46be6a0b099e 615 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 615 38.934 T 22-04-2016 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: REACT_17015 L21SP4_RS03715 7503e3184f1afec6de1e46be6a0b099e 615 Gene3D G3DSA:3.40.50.10490 447 615 8.9E-57 T 22-04-2016 L21SP4_RS03715 7503e3184f1afec6de1e46be6a0b099e 615 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 615 3.5E-234 T 22-04-2016 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: REACT_17015 L21SP4_RS03715 7503e3184f1afec6de1e46be6a0b099e 615 Gene3D G3DSA:3.40.50.10490 247 446 2.2E-65 T 22-04-2016 L21SP4_RS03715 7503e3184f1afec6de1e46be6a0b099e 615 Gene3D G3DSA:3.60.20.10 2 237 1.4E-70 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal L21SP4_RS03715 7503e3184f1afec6de1e46be6a0b099e 615 PANTHER PTHR10937 1 615 1.7E-293 T 22-04-2016 L21SP4_RS03715 7503e3184f1afec6de1e46be6a0b099e 615 Pfam PF13522 Glutamine amidotransferase domain 63 194 5.9E-21 T 22-04-2016 L21SP4_RS03715 7503e3184f1afec6de1e46be6a0b099e 615 SUPERFAMILY SSF53697 249 615 3.43E-102 T 22-04-2016 L21SP4_RS03715 7503e3184f1afec6de1e46be6a0b099e 615 SUPERFAMILY SSF56235 2 222 1.2E-66 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal L21SP4_RS07405 0ac6adb8a4e601b5150c9b9b448251a5 104 PANTHER PTHR33755 1 97 7.9E-30 T 22-04-2016 L21SP4_RS07405 0ac6adb8a4e601b5150c9b9b448251a5 104 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 4 90 2.3E-19 T 22-04-2016 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family L21SP4_RS07405 0ac6adb8a4e601b5150c9b9b448251a5 104 PANTHER PTHR33755:SF5 1 97 7.9E-30 T 22-04-2016 L21SP4_RS00545 9ae12a07a41902149784a8262e1dda5b 512 PIRSF PIRSF017184 1 511 2.5E-141 T 22-04-2016 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 L21SP4_RS00545 9ae12a07a41902149784a8262e1dda5b 512 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 238 511 23.017 T 22-04-2016 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 L21SP4_RS00545 9ae12a07a41902149784a8262e1dda5b 512 Gene3D G3DSA:3.40.50.10260 1 245 1.0E-61 T 22-04-2016 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 L21SP4_RS00545 9ae12a07a41902149784a8262e1dda5b 512 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 5 220 23.471 T 22-04-2016 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 L21SP4_RS00545 9ae12a07a41902149784a8262e1dda5b 512 Pfam PF01256 Carbohydrate kinase 262 503 1.0E-56 T 22-04-2016 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 L21SP4_RS00545 9ae12a07a41902149784a8262e1dda5b 512 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 446 456 - T 22-04-2016 IPR017953 Carbohydrate kinase, predicted, conserved site L21SP4_RS00545 9ae12a07a41902149784a8262e1dda5b 512 PANTHER PTHR12592:SF0 1 512 1.3E-126 T 22-04-2016 L21SP4_RS00545 9ae12a07a41902149784a8262e1dda5b 512 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 4 220 1.3E-38 T 22-04-2016 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 L21SP4_RS00545 9ae12a07a41902149784a8262e1dda5b 512 SUPERFAMILY SSF53613 240 508 2.34E-71 T 22-04-2016 IPR029056 Ribokinase-like L21SP4_RS00545 9ae12a07a41902149784a8262e1dda5b 512 SUPERFAMILY SSF64153 1 259 7.85E-58 T 22-04-2016 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 L21SP4_RS00545 9ae12a07a41902149784a8262e1dda5b 512 Pfam PF03853 YjeF-related protein N-terminus 25 199 2.4E-40 T 22-04-2016 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 L21SP4_RS00545 9ae12a07a41902149784a8262e1dda5b 512 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 246 506 3.2E-59 T 22-04-2016 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 L21SP4_RS00545 9ae12a07a41902149784a8262e1dda5b 512 Gene3D G3DSA:3.40.1190.20 246 508 3.8E-85 T 22-04-2016 IPR029056 Ribokinase-like L21SP4_RS00545 9ae12a07a41902149784a8262e1dda5b 512 PANTHER PTHR12592 1 512 1.3E-126 T 22-04-2016 L21SP4_RS05060 8b4a14f7676794fdbb456467d4f9323a 295 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 7 89 6.7E-18 T 22-04-2016 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 L21SP4_RS05060 8b4a14f7676794fdbb456467d4f9323a 295 Gene3D G3DSA:1.10.443.10 111 286 1.2E-58 T 22-04-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 L21SP4_RS05060 8b4a14f7676794fdbb456467d4f9323a 295 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 2 295 31.672 T 22-04-2016 IPR023009 Tyrosine recombinase XerC/XerD L21SP4_RS05060 8b4a14f7676794fdbb456467d4f9323a 295 SUPERFAMILY SSF47823 4 96 2.94E-18 T 22-04-2016 IPR010998 Integrase, Lambda-type, N-terminal L21SP4_RS05060 8b4a14f7676794fdbb456467d4f9323a 295 Hamap MF_01807 Tyrosine recombinase XerD [xerD]. 2 295 53.747 T 22-04-2016 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 L21SP4_RS05060 8b4a14f7676794fdbb456467d4f9323a 295 Pfam PF00589 Phage integrase family 111 280 5.2E-47 T 22-04-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 L21SP4_RS05060 8b4a14f7676794fdbb456467d4f9323a 295 Gene3D G3DSA:1.10.150.130 3 97 9.6E-23 T 22-04-2016 IPR023109 Integrase/recombinase, N-terminal L21SP4_RS05060 8b4a14f7676794fdbb456467d4f9323a 295 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 7 295 6.2E-105 T 22-04-2016 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 L21SP4_RS05060 8b4a14f7676794fdbb456467d4f9323a 295 SUPERFAMILY SSF56349 108 293 2.27E-58 T 22-04-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 L21SP4_RS05060 8b4a14f7676794fdbb456467d4f9323a 295 PANTHER PTHR30349:SF5 1 295 7.9E-105 T 22-04-2016 L21SP4_RS05060 8b4a14f7676794fdbb456467d4f9323a 295 PANTHER PTHR30349 1 295 7.9E-105 T 22-04-2016 L21SP4_RS09420 2c034ff402e123206c3d52deac297581 384 Gene3D G3DSA:1.10.10.60 331 379 2.3E-17 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS09420 2c034ff402e123206c3d52deac297581 384 SUPERFAMILY SSF53822 49 292 6.13E-27 T 22-04-2016 IPR028082 Periplasmic binding protein-like I L21SP4_RS09420 2c034ff402e123206c3d52deac297581 384 Pfam PF13377 Periplasmic binding protein-like domain 106 270 2.1E-25 T 22-04-2016 L21SP4_RS09420 2c034ff402e123206c3d52deac297581 384 SMART SM00342 294 377 2.2E-28 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP4_RS09420 2c034ff402e123206c3d52deac297581 384 Gene3D G3DSA:3.40.50.2300 90 270 1.7E-24 T 22-04-2016 L21SP4_RS09420 2c034ff402e123206c3d52deac297581 384 Pfam PF12833 Helix-turn-helix domain 301 377 2.2E-20 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP4_RS09420 2c034ff402e123206c3d52deac297581 384 SUPERFAMILY SSF46689 277 324 2.5E-8 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS09420 2c034ff402e123206c3d52deac297581 384 Gene3D G3DSA:1.10.10.60 277 330 1.5E-11 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS09420 2c034ff402e123206c3d52deac297581 384 PANTHER PTHR30146 18 313 2.0E-38 T 22-04-2016 L21SP4_RS09420 2c034ff402e123206c3d52deac297581 384 SUPERFAMILY SSF46689 330 378 1.88E-12 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS09420 2c034ff402e123206c3d52deac297581 384 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 331 373 - T 22-04-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 L21SP4_RS07865 73a2297db0e1b02b8ad18f5320941e52 101 SUPERFAMILY SSF46785 2 61 4.43E-14 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS07865 73a2297db0e1b02b8ad18f5320941e52 101 Gene3D G3DSA:1.10.10.10 7 46 7.8E-7 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS07865 73a2297db0e1b02b8ad18f5320941e52 101 Pfam PF09012 FeoC like transcriptional regulator 1 63 3.6E-15 T 22-04-2016 IPR015102 Transcriptional regulator HTH-type, FeoC L21SP4_RS00455 00fd6948e83e33d6990b6df66233d477 366 PANTHER PTHR24423 1 366 2.8E-127 T 22-04-2016 L21SP4_RS00455 00fd6948e83e33d6990b6df66233d477 366 Gene3D G3DSA:3.40.50.2300 242 363 1.2E-27 T 22-04-2016 L21SP4_RS00455 00fd6948e83e33d6990b6df66233d477 366 SMART SM00387 100 223 6.9E-33 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS00455 00fd6948e83e33d6990b6df66233d477 366 PRINTS PR00344 Bacterial sensor protein C-terminal signature 183 201 5.5E-19 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS00455 00fd6948e83e33d6990b6df66233d477 366 PRINTS PR00344 Bacterial sensor protein C-terminal signature 170 180 5.5E-19 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS00455 00fd6948e83e33d6990b6df66233d477 366 PRINTS PR00344 Bacterial sensor protein C-terminal signature 152 166 5.5E-19 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS00455 00fd6948e83e33d6990b6df66233d477 366 PRINTS PR00344 Bacterial sensor protein C-terminal signature 207 220 5.5E-19 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 L21SP4_RS00455 00fd6948e83e33d6990b6df66233d477 366 Pfam PF00512 His Kinase A (phospho-acceptor) domain 1 57 1.5E-6 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS00455 00fd6948e83e33d6990b6df66233d477 366 Gene3D G3DSA:3.30.565.10 58 221 6.5E-43 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS00455 00fd6948e83e33d6990b6df66233d477 366 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 101 221 6.7E-21 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS00455 00fd6948e83e33d6990b6df66233d477 366 SUPERFAMILY SSF52172 243 361 2.13E-25 T 22-04-2016 IPR011006 CheY-like superfamily L21SP4_RS00455 00fd6948e83e33d6990b6df66233d477 366 SUPERFAMILY SSF55874 49 221 2.36E-43 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS00455 00fd6948e83e33d6990b6df66233d477 366 SUPERFAMILY SSF47384 1 57 4.9E-7 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP4_RS00455 00fd6948e83e33d6990b6df66233d477 366 Pfam PF00072 Response regulator receiver domain 245 356 9.3E-16 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 L21SP4_RS00455 00fd6948e83e33d6990b6df66233d477 366 SMART SM00448 242 356 7.0E-17 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 L21SP4_RS00455 00fd6948e83e33d6990b6df66233d477 366 PANTHER PTHR24423:SF458 1 366 2.8E-127 T 22-04-2016 L21SP4_RS01480 0689e492bcfbe27cd3e06b9012b4ff1a 895 SUPERFAMILY SSF82866 189 400 3.01E-31 T 22-04-2016 L21SP4_RS01480 0689e492bcfbe27cd3e06b9012b4ff1a 895 PANTHER PTHR33406 1 113 6.1E-52 T 22-04-2016 L21SP4_RS01480 0689e492bcfbe27cd3e06b9012b4ff1a 895 PANTHER PTHR33406 144 888 6.1E-52 T 22-04-2016 L21SP4_RS01480 0689e492bcfbe27cd3e06b9012b4ff1a 895 Gene3D G3DSA:1.20.1640.10 208 400 6.5E-38 T 22-04-2016 L21SP4_RS01480 0689e492bcfbe27cd3e06b9012b4ff1a 895 Gene3D G3DSA:1.20.1640.10 683 890 1.7E-26 T 22-04-2016 L21SP4_RS01480 0689e492bcfbe27cd3e06b9012b4ff1a 895 SUPERFAMILY SSF82866 668 887 2.09E-27 T 22-04-2016 L21SP4_RS01480 0689e492bcfbe27cd3e06b9012b4ff1a 895 Pfam PF03176 MMPL family 599 891 5.6E-16 T 22-04-2016 IPR004869 Membrane transport protein, MMPL domain GO:0016020 L21SP4_RS01480 0689e492bcfbe27cd3e06b9012b4ff1a 895 Pfam PF03176 MMPL family 176 398 3.0E-14 T 22-04-2016 IPR004869 Membrane transport protein, MMPL domain GO:0016020 L21SP4_RS07045 6a14404312c4f2834e9c3bf2133a6052 614 SUPERFAMILY SSF110942 492 605 2.75E-29 T 22-04-2016 L21SP4_RS07045 6a14404312c4f2834e9c3bf2133a6052 614 PANTHER PTHR11528 4 606 1.7E-283 T 22-04-2016 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 L21SP4_RS07045 6a14404312c4f2834e9c3bf2133a6052 614 PRINTS PR00775 90kDa heat shock protein signature 169 186 9.9E-61 T 22-04-2016 IPR020575 Heat shock protein Hsp90, N-terminal L21SP4_RS07045 6a14404312c4f2834e9c3bf2133a6052 614 PRINTS PR00775 90kDa heat shock protein signature 187 205 9.9E-61 T 22-04-2016 IPR020575 Heat shock protein Hsp90, N-terminal L21SP4_RS07045 6a14404312c4f2834e9c3bf2133a6052 614 PRINTS PR00775 90kDa heat shock protein signature 120 142 9.9E-61 T 22-04-2016 IPR020575 Heat shock protein Hsp90, N-terminal L21SP4_RS07045 6a14404312c4f2834e9c3bf2133a6052 614 PRINTS PR00775 90kDa heat shock protein signature 4 24 9.9E-61 T 22-04-2016 IPR020575 Heat shock protein Hsp90, N-terminal L21SP4_RS07045 6a14404312c4f2834e9c3bf2133a6052 614 PRINTS PR00775 90kDa heat shock protein signature 25 47 9.9E-61 T 22-04-2016 IPR020575 Heat shock protein Hsp90, N-terminal L21SP4_RS07045 6a14404312c4f2834e9c3bf2133a6052 614 PRINTS PR00775 90kDa heat shock protein signature 74 91 9.9E-61 T 22-04-2016 IPR020575 Heat shock protein Hsp90, N-terminal L21SP4_RS07045 6a14404312c4f2834e9c3bf2133a6052 614 PRINTS PR00775 90kDa heat shock protein signature 92 109 9.9E-61 T 22-04-2016 IPR020575 Heat shock protein Hsp90, N-terminal L21SP4_RS07045 6a14404312c4f2834e9c3bf2133a6052 614 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 27 179 2.2E-11 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS07045 6a14404312c4f2834e9c3bf2133a6052 614 Gene3D G3DSA:3.30.565.10 5 222 1.5E-83 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS07045 6a14404312c4f2834e9c3bf2133a6052 614 PIRSF PIRSF002583 1 612 2.5E-209 T 22-04-2016 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 L21SP4_RS07045 6a14404312c4f2834e9c3bf2133a6052 614 Pfam PF00183 Hsp90 protein 208 606 7.5E-127 T 22-04-2016 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 L21SP4_RS07045 6a14404312c4f2834e9c3bf2133a6052 614 SUPERFAMILY SSF55874 4 213 1.31E-63 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS07045 6a14404312c4f2834e9c3bf2133a6052 614 PANTHER PTHR11528:SF44 4 606 1.7E-283 T 22-04-2016 L21SP4_RS07045 6a14404312c4f2834e9c3bf2133a6052 614 Hamap MF_00505 Chaperone protein HtpG [htpG]. 1 606 28.319 T 22-04-2016 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 L21SP4_RS07045 6a14404312c4f2834e9c3bf2133a6052 614 ProSitePatterns PS00298 Heat shock hsp90 proteins family signature. 24 33 - T 22-04-2016 IPR019805 Heat shock protein Hsp90, conserved site GO:0005524|GO:0006457|GO:0006950|GO:0051082 L21SP4_RS07045 6a14404312c4f2834e9c3bf2133a6052 614 SUPERFAMILY SSF54211 215 468 1.21E-85 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold L21SP4_RS06125 3c842cba4960abda16919afd17fa0b36 497 PANTHER PTHR11963 40 493 5.7E-141 T 22-04-2016 L21SP4_RS06125 3c842cba4960abda16919afd17fa0b36 497 Gene3D G3DSA:3.40.220.10 41 138 2.2E-6 T 22-04-2016 L21SP4_RS06125 3c842cba4960abda16919afd17fa0b36 497 SUPERFAMILY SSF53187 185 494 7.95E-101 T 22-04-2016 L21SP4_RS06125 3c842cba4960abda16919afd17fa0b36 497 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 345 352 - T 22-04-2016 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 L21SP4_RS06125 3c842cba4960abda16919afd17fa0b36 497 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 190 490 4.2E-103 T 22-04-2016 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 L21SP4_RS06125 3c842cba4960abda16919afd17fa0b36 497 PRINTS PR00481 Cytosol aminopeptidase signature 260 277 5.9E-47 T 22-04-2016 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 L21SP4_RS06125 3c842cba4960abda16919afd17fa0b36 497 PRINTS PR00481 Cytosol aminopeptidase signature 282 303 5.9E-47 T 22-04-2016 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 L21SP4_RS06125 3c842cba4960abda16919afd17fa0b36 497 PRINTS PR00481 Cytosol aminopeptidase signature 319 340 5.9E-47 T 22-04-2016 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 L21SP4_RS06125 3c842cba4960abda16919afd17fa0b36 497 PRINTS PR00481 Cytosol aminopeptidase signature 341 361 5.9E-47 T 22-04-2016 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 L21SP4_RS06125 3c842cba4960abda16919afd17fa0b36 497 PRINTS PR00481 Cytosol aminopeptidase signature 369 384 5.9E-47 T 22-04-2016 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 L21SP4_RS06125 3c842cba4960abda16919afd17fa0b36 497 SUPERFAMILY SSF52949 39 138 2.53E-5 T 22-04-2016 L21SP4_RS06125 3c842cba4960abda16919afd17fa0b36 497 Gene3D G3DSA:3.40.630.10 185 494 8.3E-110 T 22-04-2016 L21SP4_RS06125 3c842cba4960abda16919afd17fa0b36 497 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 44 127 2.5E-9 T 22-04-2016 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 L21SP4_RS06125 3c842cba4960abda16919afd17fa0b36 497 PANTHER PTHR11963:SF13 40 493 5.7E-141 T 22-04-2016 L21SP4_RS07480 50b37eda4400973e15e49d58b058d0e8 71 Pfam PF13619 KTSC domain 9 66 5.8E-24 T 22-04-2016 IPR025309 KTSC domain L21SP4_RS06765 339e75df517a5021e26aca2abdd1e400 290 SUPERFAMILY SSF55804 147 282 3.92E-19 T 22-04-2016 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: REACT_15518 L21SP4_RS06765 339e75df517a5021e26aca2abdd1e400 290 Pfam PF02591 C4-type zinc ribbon domain 82 114 5.9E-10 T 22-04-2016 IPR003743 C4-type zinc ribbon domain L21SP4_RS06765 339e75df517a5021e26aca2abdd1e400 290 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 155 283 1.2E-18 T 22-04-2016 IPR002178 PTS EIIA type-2 domain KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- L21SP4_RS06765 339e75df517a5021e26aca2abdd1e400 290 PANTHER PTHR30505 155 290 1.7E-12 T 22-04-2016 L21SP4_RS06765 339e75df517a5021e26aca2abdd1e400 290 Gene3D G3DSA:3.40.930.10 145 285 1.3E-22 T 22-04-2016 IPR002178 PTS EIIA type-2 domain KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- L21SP4_RS09985 08a2af1f928b0566705917c127bc0756 471 Pfam PF01040 UbiA prenyltransferase family 204 439 4.7E-23 T 22-04-2016 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 L21SP4_RS09985 08a2af1f928b0566705917c127bc0756 471 SUPERFAMILY SSF56784 4 16 1.63E-12 T 22-04-2016 IPR023214 HAD-like domain L21SP4_RS09985 08a2af1f928b0566705917c127bc0756 471 SUPERFAMILY SSF56784 56 155 1.63E-12 T 22-04-2016 IPR023214 HAD-like domain L21SP4_RS09985 08a2af1f928b0566705917c127bc0756 471 Gene3D G3DSA:3.40.50.1000 47 169 5.3E-7 T 22-04-2016 IPR023214 HAD-like domain L21SP4_RS09985 08a2af1f928b0566705917c127bc0756 471 PANTHER PTHR11048 163 341 1.4E-36 T 22-04-2016 L21SP4_RS09985 08a2af1f928b0566705917c127bc0756 471 PANTHER PTHR11048:SF5 163 341 1.4E-36 T 22-04-2016 L21SP4_RS09985 08a2af1f928b0566705917c127bc0756 471 Pfam PF12710 haloacid dehalogenase-like hydrolase 9 145 2.8E-7 T 22-04-2016 L21SP4_RS03920 69fa17bffbcb8fdea87f205213817b84 581 PANTHER PTHR30557 175 578 1.9E-290 T 22-04-2016 L21SP4_RS03920 69fa17bffbcb8fdea87f205213817b84 581 PANTHER PTHR30557 9 148 1.9E-290 T 22-04-2016 L21SP4_RS03920 69fa17bffbcb8fdea87f205213817b84 581 Pfam PF01964 Radical SAM ThiC family 126 574 2.7E-179 T 22-04-2016 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890|UniPathway: UPA00060 L21SP4_RS03920 69fa17bffbcb8fdea87f205213817b84 581 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 125 576 1.1E-179 T 22-04-2016 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890|UniPathway: UPA00060 L21SP4_RS03920 69fa17bffbcb8fdea87f205213817b84 581 Pfam PF13667 ThiC-associated domain 46 120 6.7E-24 T 22-04-2016 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890|UniPathway: UPA00060 L21SP4_RS03920 69fa17bffbcb8fdea87f205213817b84 581 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 125 580 52.085 T 22-04-2016 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890|UniPathway: UPA00060 L21SP4_RS03920 69fa17bffbcb8fdea87f205213817b84 581 PANTHER PTHR30557:SF1 175 578 1.9E-290 T 22-04-2016 L21SP4_RS03920 69fa17bffbcb8fdea87f205213817b84 581 PANTHER PTHR30557:SF1 9 148 1.9E-290 T 22-04-2016 L21SP4_RS11165 fe869f4d54893d22f6898c67f80ab3f9 447 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 4 447 2.8E-90 T 22-04-2016 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase L21SP4_RS11165 fe869f4d54893d22f6898c67f80ab3f9 447 Pfam PF13727 CoA-binding domain 59 176 1.6E-6 T 22-04-2016 L21SP4_RS11165 fe869f4d54893d22f6898c67f80ab3f9 447 Pfam PF02397 Bacterial sugar transferase 252 441 4.8E-44 T 22-04-2016 IPR003362 Bacterial sugar transferase L21SP4_RS11165 fe869f4d54893d22f6898c67f80ab3f9 447 PANTHER PTHR30576 1 447 7.8E-95 T 22-04-2016 L21SP4_RS11165 fe869f4d54893d22f6898c67f80ab3f9 447 PANTHER PTHR30576:SF4 1 447 7.8E-95 T 22-04-2016 L21SP4_RS01545 b0eba6a33637c23b7041bd459133cd81 856 Gene3D G3DSA:2.160.20.10 495 582 1.0E-7 T 22-04-2016 IPR012334 Pectin lyase fold L21SP4_RS01545 b0eba6a33637c23b7041bd459133cd81 856 Gene3D G3DSA:2.160.20.10 316 439 1.0E-7 T 22-04-2016 IPR012334 Pectin lyase fold L21SP4_RS01545 b0eba6a33637c23b7041bd459133cd81 856 Gene3D G3DSA:2.160.20.10 622 659 1.0E-7 T 22-04-2016 IPR012334 Pectin lyase fold L21SP4_RS01545 b0eba6a33637c23b7041bd459133cd81 856 SUPERFAMILY SSF51126 313 401 1.15E-17 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor L21SP4_RS01545 b0eba6a33637c23b7041bd459133cd81 856 SUPERFAMILY SSF51126 428 527 1.15E-17 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor L21SP4_RS01545 b0eba6a33637c23b7041bd459133cd81 856 SUPERFAMILY SSF51126 563 660 1.15E-17 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor L21SP4_RS02435 42919f8daff819ccfaf81e94c239d9e0 146 PANTHER PTHR40099 1 143 5.5E-44 T 22-04-2016 L21SP4_RS02435 42919f8daff819ccfaf81e94c239d9e0 146 SUPERFAMILY SSF55021 71 141 8.24E-16 T 22-04-2016 L21SP4_RS02435 42919f8daff819ccfaf81e94c239d9e0 146 PANTHER PTHR40099:SF1 1 143 5.5E-44 T 22-04-2016 L21SP4_RS02435 42919f8daff819ccfaf81e94c239d9e0 146 SUPERFAMILY SSF55021 3 69 2.24E-14 T 22-04-2016 L21SP4_RS02435 42919f8daff819ccfaf81e94c239d9e0 146 Gene3D G3DSA:3.30.70.260 67 125 3.6E-9 T 22-04-2016 L21SP4_RS02435 42919f8daff819ccfaf81e94c239d9e0 146 Pfam PF01842 ACT domain 74 121 3.6E-7 T 22-04-2016 IPR002912 ACT domain GO:0008152|GO:0016597 L21SP4_RS02435 42919f8daff819ccfaf81e94c239d9e0 146 Gene3D G3DSA:3.30.70.260 4 66 1.6E-8 T 22-04-2016 L21SP4_RS00530 eb5cf0895dd8643e853a4e5c92db7c2c 219 Pfam PF01351 Ribonuclease HII 23 207 9.6E-36 T 22-04-2016 IPR024567 Ribonuclease HII/HIII domain L21SP4_RS00530 eb5cf0895dd8643e853a4e5c92db7c2c 219 Gene3D G3DSA:3.30.420.10 21 169 2.6E-42 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS00530 eb5cf0895dd8643e853a4e5c92db7c2c 219 PANTHER PTHR10954 10 210 1.4E-68 T 22-04-2016 IPR001352 Ribonuclease HII/HIII GO:0003723|GO:0004523 L21SP4_RS00530 eb5cf0895dd8643e853a4e5c92db7c2c 219 SUPERFAMILY SSF53098 10 211 6.68E-64 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS00530 eb5cf0895dd8643e853a4e5c92db7c2c 219 Hamap MF_00052_B Ribonuclease HII [rnhB]. 21 208 35.597 T 22-04-2016 IPR022898 Ribonuclease HII GO:0004523 L21SP4_RS11720 1f3dc07f59ffd24aec9c2874db519b70 410 Pfam PF01609 Transposase DDE domain 130 346 4.3E-24 T 22-04-2016 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 L21SP4_RS11720 1f3dc07f59ffd24aec9c2874db519b70 410 PANTHER PTHR33258:SF1 8 382 9.6E-36 T 22-04-2016 L21SP4_RS11720 1f3dc07f59ffd24aec9c2874db519b70 410 PANTHER PTHR33258 8 382 9.6E-36 T 22-04-2016 L21SP4_RS11720 1f3dc07f59ffd24aec9c2874db519b70 410 Gene3D G3DSA:3.90.350.10 293 321 1.1E-4 T 22-04-2016 IPR014736 Transposase, Tn5-like, core L21SP4_RS11720 1f3dc07f59ffd24aec9c2874db519b70 410 Pfam PF14294 Domain of unknown function (DUF4372) 10 71 9.5E-12 T 22-04-2016 IPR025399 Domain of unknown function DUF4372 L21SP4_RS11720 1f3dc07f59ffd24aec9c2874db519b70 410 SUPERFAMILY SSF53098 128 367 1.21E-22 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS04280 374611b85fdc898a3bb4657eb8b0842b 436 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 13 425 7.6E-116 T 22-04-2016 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit L21SP4_RS04280 374611b85fdc898a3bb4657eb8b0842b 436 PIRSF PIRSF006066 5 436 5.9E-153 T 22-04-2016 IPR004681 TRAP transporter permease protein GO:0016021 L21SP4_RS04280 374611b85fdc898a3bb4657eb8b0842b 436 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 22 430 5.1E-134 T 22-04-2016 IPR004681 TRAP transporter permease protein GO:0016021 L21SP4_RS04280 374611b85fdc898a3bb4657eb8b0842b 436 PANTHER PTHR33362 5 434 7.9E-170 T 22-04-2016 L21SP4_RS04280 374611b85fdc898a3bb4657eb8b0842b 436 PANTHER PTHR33362:SF2 5 434 7.9E-170 T 22-04-2016 L21SP4_RS09870 55747a56087c9a9db078653640148061 802 PANTHER PTHR12526:SF391 9 793 0.0 T 22-04-2016 L21SP4_RS09870 55747a56087c9a9db078653640148061 802 SUPERFAMILY SSF53756 284 753 5.1E-49 T 22-04-2016 L21SP4_RS09870 55747a56087c9a9db078653640148061 802 Gene3D G3DSA:3.40.50.2000 553 735 1.3E-17 T 22-04-2016 L21SP4_RS09870 55747a56087c9a9db078653640148061 802 Pfam PF00534 Glycosyl transferases group 1 555 716 3.2E-27 T 22-04-2016 IPR001296 Glycosyl transferase, family 1 L21SP4_RS09870 55747a56087c9a9db078653640148061 802 PANTHER PTHR12526 9 793 0.0 T 22-04-2016 L21SP4_RS09870 55747a56087c9a9db078653640148061 802 TIGRFAM TIGR02470 sucr_synth: sucrose synthase 16 790 0.0 T 22-04-2016 IPR012820 Sucrose synthase, plant/cyanobacteria GO:0005985|GO:0016157 KEGG: 00500+2.4.1.13|MetaCyc: PWY-3801 L21SP4_RS09870 55747a56087c9a9db078653640148061 802 Pfam PF00862 Sucrose synthase 3 543 2.1E-228 T 22-04-2016 IPR000368 Sucrose synthase GO:0005985|GO:0016157 L21SP4_RS03325 2623c36257576b6d6b2779a14f02f30e 151 PANTHER PTHR30015 1 125 3.0E-23 T 22-04-2016 L21SP4_RS03325 2623c36257576b6d6b2779a14f02f30e 151 Gene3D G3DSA:3.40.1350.10 5 118 9.5E-16 T 22-04-2016 IPR011856 tRNA endonuclease-like domain GO:0003676|GO:0004518 L21SP4_RS03325 2623c36257576b6d6b2779a14f02f30e 151 SUPERFAMILY SSF52980 6 122 6.97E-14 T 22-04-2016 IPR011335 Restriction endonuclease type II-like L21SP4_RS03325 2623c36257576b6d6b2779a14f02f30e 151 Pfam PF04471 Restriction endonuclease 3 117 1.0E-27 T 22-04-2016 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 L21SP4_RS03325 2623c36257576b6d6b2779a14f02f30e 151 PANTHER PTHR30015:SF4 1 125 3.0E-23 T 22-04-2016 L21SP4_RS09995 2e0573095fc4530a607336a2ebdff2af 350 SUPERFAMILY SSF51126 14 328 3.14E-29 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor L21SP4_RS09995 2e0573095fc4530a607336a2ebdff2af 350 Gene3D G3DSA:2.160.20.10 131 328 4.8E-17 T 22-04-2016 IPR012334 Pectin lyase fold L21SP4_RS09995 2e0573095fc4530a607336a2ebdff2af 350 Pfam PF13229 Right handed beta helix region 113 244 6.1E-6 T 22-04-2016 L21SP4_RS02170 a4cb506460e53cb9f36aa2c5f9fcf12e 412 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 6 411 4.5E-144 T 22-04-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 L21SP4_RS02170 a4cb506460e53cb9f36aa2c5f9fcf12e 412 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 286 389 1.7E-18 T 22-04-2016 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 Reactome: REACT_13 L21SP4_RS02170 a4cb506460e53cb9f36aa2c5f9fcf12e 412 PRINTS PR01181 Diaminopimelate decarboxylase signature 75 92 6.4E-30 T 22-04-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 L21SP4_RS02170 a4cb506460e53cb9f36aa2c5f9fcf12e 412 PRINTS PR01181 Diaminopimelate decarboxylase signature 299 317 6.4E-30 T 22-04-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 L21SP4_RS02170 a4cb506460e53cb9f36aa2c5f9fcf12e 412 PRINTS PR01181 Diaminopimelate decarboxylase signature 164 173 6.4E-30 T 22-04-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 L21SP4_RS02170 a4cb506460e53cb9f36aa2c5f9fcf12e 412 PRINTS PR01181 Diaminopimelate decarboxylase signature 379 401 6.4E-30 T 22-04-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 L21SP4_RS02170 a4cb506460e53cb9f36aa2c5f9fcf12e 412 PANTHER PTHR11482:SF5 1 412 3.3E-161 T 22-04-2016 L21SP4_RS02170 a4cb506460e53cb9f36aa2c5f9fcf12e 412 SUPERFAMILY SSF51419 26 283 1.6E-75 T 22-04-2016 IPR029066 PLP-binding barrel L21SP4_RS02170 a4cb506460e53cb9f36aa2c5f9fcf12e 412 SUPERFAMILY SSF50621 258 411 6.49E-55 T 22-04-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 L21SP4_RS02170 a4cb506460e53cb9f36aa2c5f9fcf12e 412 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 369 382 3.5E-18 T 22-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 L21SP4_RS02170 a4cb506460e53cb9f36aa2c5f9fcf12e 412 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 77 89 3.5E-18 T 22-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 L21SP4_RS02170 a4cb506460e53cb9f36aa2c5f9fcf12e 412 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 271 290 3.5E-18 T 22-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 L21SP4_RS02170 a4cb506460e53cb9f36aa2c5f9fcf12e 412 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 190 203 3.5E-18 T 22-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 L21SP4_RS02170 a4cb506460e53cb9f36aa2c5f9fcf12e 412 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 57 75 3.5E-18 T 22-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 L21SP4_RS02170 a4cb506460e53cb9f36aa2c5f9fcf12e 412 PANTHER PTHR11482 1 412 3.3E-161 T 22-04-2016 L21SP4_RS02170 a4cb506460e53cb9f36aa2c5f9fcf12e 412 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 15 412 42.007 T 22-04-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 L21SP4_RS02170 a4cb506460e53cb9f36aa2c5f9fcf12e 412 Gene3D G3DSA:2.40.37.10 267 411 5.2E-49 T 22-04-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 L21SP4_RS02170 a4cb506460e53cb9f36aa2c5f9fcf12e 412 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 41 281 1.4E-52 T 22-04-2016 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 Reactome: REACT_13 L21SP4_RS02170 a4cb506460e53cb9f36aa2c5f9fcf12e 412 Gene3D G3DSA:3.20.20.10 36 266 4.7E-75 T 22-04-2016 IPR029066 PLP-binding barrel L21SP4_RS01415 db02765d603746dfbf12cbaaea7e3ef0 229 SMART SM00862 154 227 8.9E-25 T 22-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 L21SP4_RS01415 db02765d603746dfbf12cbaaea7e3ef0 229 SMART SM00448 4 117 2.1E-45 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 L21SP4_RS01415 db02765d603746dfbf12cbaaea7e3ef0 229 SUPERFAMILY SSF46894 130 227 1.59E-28 T 22-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 L21SP4_RS01415 db02765d603746dfbf12cbaaea7e3ef0 229 Gene3D G3DSA:3.40.50.2300 6 129 2.3E-44 T 22-04-2016 L21SP4_RS01415 db02765d603746dfbf12cbaaea7e3ef0 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 227 2.8E-23 T 22-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 L21SP4_RS01415 db02765d603746dfbf12cbaaea7e3ef0 229 PANTHER PTHR26402 4 229 1.3E-89 T 22-04-2016 L21SP4_RS01415 db02765d603746dfbf12cbaaea7e3ef0 229 SUPERFAMILY SSF52172 5 129 1.42E-43 T 22-04-2016 IPR011006 CheY-like superfamily L21SP4_RS01415 db02765d603746dfbf12cbaaea7e3ef0 229 Gene3D G3DSA:1.10.10.10 131 228 1.5E-31 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS01415 db02765d603746dfbf12cbaaea7e3ef0 229 PANTHER PTHR26402:SF50 4 229 1.3E-89 T 22-04-2016 L21SP4_RS01415 db02765d603746dfbf12cbaaea7e3ef0 229 Pfam PF00072 Response regulator receiver domain 7 118 2.0E-30 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 L21SP4_RS03395 217ac587182db537e6725801601c5f9e 103 SUPERFAMILY SSF52309 1 99 2.96E-7 T 22-04-2016 L21SP4_RS03395 217ac587182db537e6725801601c5f9e 103 Gene3D G3DSA:3.40.50.10400 1 102 7.3E-6 T 22-04-2016 IPR027269 Hypothetical PA1492 domain L21SP4_RS08205 f0d2eb736799abb6c00d3d1af79b6515 209 ProSitePatterns PS00160 KDPG and KHG aldolases Schiff-base forming residue. 124 137 - T 22-04-2016 IPR031338 KDPG/KHG aldolase, active site 2 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 L21SP4_RS08205 f0d2eb736799abb6c00d3d1af79b6515 209 Pfam PF01081 KDPG and KHG aldolase 8 200 1.5E-64 T 22-04-2016 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 L21SP4_RS08205 f0d2eb736799abb6c00d3d1af79b6515 209 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 5 206 1.5E-68 T 22-04-2016 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 L21SP4_RS08205 f0d2eb736799abb6c00d3d1af79b6515 209 Gene3D G3DSA:3.20.20.70 3 207 3.5E-70 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP4_RS08205 f0d2eb736799abb6c00d3d1af79b6515 209 PANTHER PTHR30246 3 209 4.2E-70 T 22-04-2016 L21SP4_RS08205 f0d2eb736799abb6c00d3d1af79b6515 209 PANTHER PTHR30246:SF0 3 209 4.2E-70 T 22-04-2016 L21SP4_RS08205 f0d2eb736799abb6c00d3d1af79b6515 209 SUPERFAMILY SSF51569 4 206 1.36E-62 T 22-04-2016 L21SP4_RS08205 f0d2eb736799abb6c00d3d1af79b6515 209 ProSitePatterns PS00159 KDPG and KHG aldolases active site. 36 45 - T 22-04-2016 IPR031337 KDPG/KHG aldolase, active site 1 KEGG: 00030+4.1.2.14|KEGG: 00330+4.1.3.16|KEGG: 00630+4.1.3.16|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562|UniPathway: UPA00227|UniPathway: UPA00856 L21SP4_RS04050 6e93954b8de3473875cbbe665ac148b4 295 SUPERFAMILY SSF55831 88 254 2.36E-24 T 22-04-2016 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|UniPathway: UPA00575 L21SP4_RS04050 6e93954b8de3473875cbbe665ac148b4 295 Gene3D G3DSA:3.30.572.10 94 254 7.3E-23 T 22-04-2016 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|UniPathway: UPA00575 L21SP4_RS04050 6e93954b8de3473875cbbe665ac148b4 295 Pfam PF00303 Thymidylate synthase 109 255 5.1E-11 T 22-04-2016 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|UniPathway: UPA00575 L21SP4_RS08615 b9c68552a15f188eccbeaed7f95238b1 276 Pfam PF01476 LysM domain 230 273 7.4E-10 T 22-04-2016 IPR018392 LysM domain L21SP4_RS08615 b9c68552a15f188eccbeaed7f95238b1 276 Pfam PF01476 LysM domain 54 97 8.4E-14 T 22-04-2016 IPR018392 LysM domain L21SP4_RS08615 b9c68552a15f188eccbeaed7f95238b1 276 Pfam PF01476 LysM domain 128 170 1.4E-14 T 22-04-2016 IPR018392 LysM domain L21SP4_RS08615 b9c68552a15f188eccbeaed7f95238b1 276 SUPERFAMILY SSF54106 127 170 1.44E-11 T 22-04-2016 IPR018392 LysM domain L21SP4_RS08615 b9c68552a15f188eccbeaed7f95238b1 276 SUPERFAMILY SSF54106 52 97 4.97E-11 T 22-04-2016 IPR018392 LysM domain L21SP4_RS08615 b9c68552a15f188eccbeaed7f95238b1 276 Gene3D G3DSA:3.10.350.10 229 274 1.6E-12 T 22-04-2016 IPR018392 LysM domain L21SP4_RS08615 b9c68552a15f188eccbeaed7f95238b1 276 Gene3D G3DSA:3.10.350.10 51 98 4.0E-15 T 22-04-2016 IPR018392 LysM domain L21SP4_RS08615 b9c68552a15f188eccbeaed7f95238b1 276 Gene3D G3DSA:3.10.350.10 126 171 5.2E-17 T 22-04-2016 IPR018392 LysM domain L21SP4_RS08615 b9c68552a15f188eccbeaed7f95238b1 276 PANTHER PTHR21666 27 169 2.3E-14 T 22-04-2016 L21SP4_RS08615 b9c68552a15f188eccbeaed7f95238b1 276 SMART SM00257 127 170 2.9E-15 T 22-04-2016 IPR018392 LysM domain L21SP4_RS08615 b9c68552a15f188eccbeaed7f95238b1 276 SMART SM00257 229 273 2.4E-9 T 22-04-2016 IPR018392 LysM domain L21SP4_RS08615 b9c68552a15f188eccbeaed7f95238b1 276 SMART SM00257 53 97 2.5E-14 T 22-04-2016 IPR018392 LysM domain L21SP4_RS08615 b9c68552a15f188eccbeaed7f95238b1 276 PANTHER PTHR21666:SF206 27 169 2.3E-14 T 22-04-2016 L21SP4_RS08615 b9c68552a15f188eccbeaed7f95238b1 276 SUPERFAMILY SSF54106 228 274 1.22E-8 T 22-04-2016 IPR018392 LysM domain L21SP4_RS01015 afe0a403f4b1d9ae9a8f094a807fc3e5 403 PIRSF PIRSF001413 1 402 4.3E-161 T 22-04-2016 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 L21SP4_RS01015 afe0a403f4b1d9ae9a8f094a807fc3e5 403 Gene3D G3DSA:3.40.50.1100 183 398 7.9E-87 T 22-04-2016 L21SP4_RS01015 afe0a403f4b1d9ae9a8f094a807fc3e5 403 PANTHER PTHR10314 13 401 2.6E-222 T 22-04-2016 L21SP4_RS01015 afe0a403f4b1d9ae9a8f094a807fc3e5 403 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 13 395 2.4E-187 T 22-04-2016 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 L21SP4_RS01015 afe0a403f4b1d9ae9a8f094a807fc3e5 403 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 87 101 - T 22-04-2016 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 L21SP4_RS01015 afe0a403f4b1d9ae9a8f094a807fc3e5 403 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 58 384 8.5E-47 T 22-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme L21SP4_RS01015 afe0a403f4b1d9ae9a8f094a807fc3e5 403 SUPERFAMILY SSF53686 9 395 6.81E-140 T 22-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme L21SP4_RS01015 afe0a403f4b1d9ae9a8f094a807fc3e5 403 Gene3D G3DSA:3.40.50.1100 105 182 4.2E-22 T 22-04-2016 L21SP4_RS01015 afe0a403f4b1d9ae9a8f094a807fc3e5 403 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 8 397 51.143 T 22-04-2016 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 L21SP4_RS01015 afe0a403f4b1d9ae9a8f094a807fc3e5 403 PANTHER PTHR10314:SF3 13 401 2.6E-222 T 22-04-2016 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 L21SP4_RS00070 491ac575b21531bee56852eef6435191 95 PRINTS PR00107 Phosphocarrier protein signature 53 70 6.5E-12 T 22-04-2016 IPR000032 Phosphocarrier HPr protein-like L21SP4_RS00070 491ac575b21531bee56852eef6435191 95 PRINTS PR00107 Phosphocarrier protein signature 13 29 6.5E-12 T 22-04-2016 IPR000032 Phosphocarrier HPr protein-like L21SP4_RS00070 491ac575b21531bee56852eef6435191 95 PRINTS PR00107 Phosphocarrier protein signature 38 53 6.5E-12 T 22-04-2016 IPR000032 Phosphocarrier HPr protein-like L21SP4_RS00070 491ac575b21531bee56852eef6435191 95 Pfam PF00381 PTS HPr component phosphorylation site 3 82 5.2E-20 T 22-04-2016 IPR000032 Phosphocarrier HPr protein-like L21SP4_RS00070 491ac575b21531bee56852eef6435191 95 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 82 3.8E-22 T 22-04-2016 IPR000032 Phosphocarrier HPr protein-like L21SP4_RS00070 491ac575b21531bee56852eef6435191 95 SUPERFAMILY SSF55594 1 86 3.79E-20 T 22-04-2016 IPR000032 Phosphocarrier HPr protein-like L21SP4_RS00070 491ac575b21531bee56852eef6435191 95 Gene3D G3DSA:3.30.1340.10 1 86 1.4E-23 T 22-04-2016 IPR000032 Phosphocarrier HPr protein-like L21SP4_RS00070 491ac575b21531bee56852eef6435191 95 PANTHER PTHR33705 1 89 4.5E-20 T 22-04-2016 L21SP4_RS09955 3de8640861c57fe49cf886155805fb3e 280 SUPERFAMILY SSF46689 175 224 4.3E-9 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS09955 3de8640861c57fe49cf886155805fb3e 280 Pfam PF02311 AraC-like ligand binding domain 21 77 1.7E-9 T 22-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 L21SP4_RS09955 3de8640861c57fe49cf886155805fb3e 280 Pfam PF12833 Helix-turn-helix domain 197 275 3.0E-21 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP4_RS09955 3de8640861c57fe49cf886155805fb3e 280 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 228 270 - T 22-04-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 L21SP4_RS09955 3de8640861c57fe49cf886155805fb3e 280 PANTHER PTHR11019 161 276 6.0E-31 T 22-04-2016 L21SP4_RS09955 3de8640861c57fe49cf886155805fb3e 280 PANTHER PTHR11019 6 121 6.0E-31 T 22-04-2016 L21SP4_RS09955 3de8640861c57fe49cf886155805fb3e 280 Gene3D G3DSA:2.60.120.280 123 179 2.2E-15 T 22-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 L21SP4_RS09955 3de8640861c57fe49cf886155805fb3e 280 Gene3D G3DSA:2.60.120.280 4 74 2.2E-15 T 22-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 L21SP4_RS09955 3de8640861c57fe49cf886155805fb3e 280 SUPERFAMILY SSF46689 227 276 1.66E-12 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS09955 3de8640861c57fe49cf886155805fb3e 280 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 243 258 1.9E-5 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 L21SP4_RS09955 3de8640861c57fe49cf886155805fb3e 280 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 258 274 1.9E-5 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 L21SP4_RS09955 3de8640861c57fe49cf886155805fb3e 280 Gene3D G3DSA:1.10.10.60 229 277 8.4E-15 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS09955 3de8640861c57fe49cf886155805fb3e 280 Gene3D G3DSA:1.10.10.60 180 228 1.5E-15 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS09955 3de8640861c57fe49cf886155805fb3e 280 SMART SM00342 191 274 3.0E-28 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP4_RS09955 3de8640861c57fe49cf886155805fb3e 280 SUPERFAMILY SSF51215 7 89 6.02E-13 T 22-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 L21SP4_RS08130 5d2d13c3e37383b73e5f0e0d15efbd58 612 Gene3D G3DSA:3.40.930.10 476 601 1.3E-21 T 22-04-2016 IPR002178 PTS EIIA type-2 domain KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- L21SP4_RS08130 5d2d13c3e37383b73e5f0e0d15efbd58 612 PANTHER PTHR11785 1 422 1.7E-86 T 22-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 L21SP4_RS08130 5d2d13c3e37383b73e5f0e0d15efbd58 612 PANTHER PTHR11785 443 469 1.7E-86 T 22-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 L21SP4_RS08130 5d2d13c3e37383b73e5f0e0d15efbd58 612 Pfam PF13520 Amino acid permease 9 390 6.4E-43 T 22-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 L21SP4_RS08130 5d2d13c3e37383b73e5f0e0d15efbd58 612 SUPERFAMILY SSF55804 475 601 3.92E-21 T 22-04-2016 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: REACT_15518 L21SP4_RS08130 5d2d13c3e37383b73e5f0e0d15efbd58 612 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 477 601 6.1E-20 T 22-04-2016 IPR002178 PTS EIIA type-2 domain KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- L21SP4_RS02005 e59ccba1b808d6ce152dc86c4a5bf1bc 476 Gene3D G3DSA:1.20.1250.20 254 454 3.4E-12 T 22-04-2016 L21SP4_RS02005 e59ccba1b808d6ce152dc86c4a5bf1bc 476 Pfam PF13347 MFS/sugar transport protein 24 455 3.1E-80 T 22-04-2016 L21SP4_RS02005 e59ccba1b808d6ce152dc86c4a5bf1bc 476 ProSitePatterns PS00872 Sodium:galactoside symporter family signature. 73 98 - T 22-04-2016 IPR018043 Sodium:galactoside symporter, conserved site GO:0005215|GO:0006814|GO:0016020 L21SP4_RS02005 e59ccba1b808d6ce152dc86c4a5bf1bc 476 PANTHER PTHR11328:SF24 22 473 6.4E-73 T 22-04-2016 L21SP4_RS02005 e59ccba1b808d6ce152dc86c4a5bf1bc 476 SUPERFAMILY SSF103473 24 449 1.96E-34 T 22-04-2016 IPR020846 Major facilitator superfamily domain L21SP4_RS02005 e59ccba1b808d6ce152dc86c4a5bf1bc 476 Gene3D G3DSA:1.20.1250.20 35 224 4.6E-15 T 22-04-2016 L21SP4_RS02005 e59ccba1b808d6ce152dc86c4a5bf1bc 476 PANTHER PTHR11328 22 473 6.4E-73 T 22-04-2016 L21SP4_RS01800 a4a4c095fdb7ae7168c503eaaed67d7e 512 PANTHER PTHR38657 1 505 5.5E-213 T 22-04-2016 L21SP4_RS01800 a4a4c095fdb7ae7168c503eaaed67d7e 512 Gene3D G3DSA:1.25.40.80 161 169 2.8E-10 T 22-04-2016 L21SP4_RS01800 a4a4c095fdb7ae7168c503eaaed67d7e 512 Gene3D G3DSA:1.25.40.80 236 320 2.8E-10 T 22-04-2016 L21SP4_RS01800 a4a4c095fdb7ae7168c503eaaed67d7e 512 SUPERFAMILY SSF48173 237 501 7.33E-56 T 22-04-2016 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain L21SP4_RS01800 a4a4c095fdb7ae7168c503eaaed67d7e 512 Pfam PF04244 Deoxyribodipyrimidine photo-lyase-related protein 12 236 4.2E-75 T 22-04-2016 IPR007357 Deoxyribodipyrimidine photolyase-related protein L21SP4_RS01800 a4a4c095fdb7ae7168c503eaaed67d7e 512 PANTHER PTHR38657:SF1 1 505 5.5E-213 T 22-04-2016 L21SP4_RS01800 a4a4c095fdb7ae7168c503eaaed67d7e 512 Gene3D G3DSA:1.10.579.10 321 408 2.1E-5 T 22-04-2016 L21SP4_RS05340 a622fb4dd4c2726bf289d01f9f200d12 167 Pfam PF00581 Rhodanese-like domain 75 160 1.2E-6 T 22-04-2016 IPR001763 Rhodanese-like domain L21SP4_RS05340 a622fb4dd4c2726bf289d01f9f200d12 167 SUPERFAMILY SSF52821 57 167 3.8E-17 T 22-04-2016 IPR001763 Rhodanese-like domain L21SP4_RS05340 a622fb4dd4c2726bf289d01f9f200d12 167 Gene3D G3DSA:3.40.250.10 57 166 3.6E-14 T 22-04-2016 IPR001763 Rhodanese-like domain L21SP4_RS08610 6675546c500d5341a231dd333d22a1ec 380 Pfam PF01098 Cell cycle protein 22 374 2.1E-98 T 22-04-2016 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 L21SP4_RS08610 6675546c500d5341a231dd333d22a1ec 380 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 22 372 1.0E-115 T 22-04-2016 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 L21SP4_RS08610 6675546c500d5341a231dd333d22a1ec 380 PANTHER PTHR30474 21 373 5.3E-126 T 22-04-2016 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 L21SP4_RS08610 6675546c500d5341a231dd333d22a1ec 380 PANTHER PTHR30474:SF2 21 373 5.3E-126 T 22-04-2016 L21SP4_RS03380 4915de29fc3110657bd2f04adf6861ef 434 Pfam PF00589 Phage integrase family 220 420 1.4E-39 T 22-04-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 L21SP4_RS03380 4915de29fc3110657bd2f04adf6861ef 434 PANTHER PTHR30349:SF28 48 294 5.9E-116 T 22-04-2016 L21SP4_RS03380 4915de29fc3110657bd2f04adf6861ef 434 PANTHER PTHR30349:SF28 313 420 5.9E-116 T 22-04-2016 L21SP4_RS03380 4915de29fc3110657bd2f04adf6861ef 434 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 120 201 5.7E-23 T 22-04-2016 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 L21SP4_RS03380 4915de29fc3110657bd2f04adf6861ef 434 SUPERFAMILY SSF56349 330 424 4.71E-45 T 22-04-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 L21SP4_RS03380 4915de29fc3110657bd2f04adf6861ef 434 SUPERFAMILY SSF56349 125 303 4.71E-45 T 22-04-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 L21SP4_RS03380 4915de29fc3110657bd2f04adf6861ef 434 TIGRFAM TIGR02249 integrase_gron: integron integrase 120 433 9.3E-111 T 22-04-2016 IPR011946 Integrase, integron-type GO:0003677|GO:0006310|GO:0015074 L21SP4_RS03380 4915de29fc3110657bd2f04adf6861ef 434 Gene3D G3DSA:1.10.443.10 217 295 2.4E-43 T 22-04-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 L21SP4_RS03380 4915de29fc3110657bd2f04adf6861ef 434 Gene3D G3DSA:1.10.443.10 339 426 2.4E-43 T 22-04-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 L21SP4_RS03380 4915de29fc3110657bd2f04adf6861ef 434 PANTHER PTHR30349 48 294 5.9E-116 T 22-04-2016 L21SP4_RS03380 4915de29fc3110657bd2f04adf6861ef 434 PANTHER PTHR30349 313 420 5.9E-116 T 22-04-2016 L21SP4_RS03380 4915de29fc3110657bd2f04adf6861ef 434 Gene3D G3DSA:1.10.150.130 130 200 2.9E-7 T 22-04-2016 IPR023109 Integrase/recombinase, N-terminal L21SP4_RS03845 95ce2f7b906d8bc54990458803ed6fac 244 SMART SM00382 32 220 1.5E-9 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS03845 95ce2f7b906d8bc54990458803ed6fac 244 Pfam PF00005 ABC transporter 24 168 1.1E-33 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 L21SP4_RS03845 95ce2f7b906d8bc54990458803ed6fac 244 TIGRFAM TIGR04406 LPS_export_lptB: LPS export ABC transporter ATP-binding protein 9 244 1.2E-105 T 22-04-2016 IPR030921 LPS export ABC transporter, ATP-binding protein LptB GO:0043190|GO:0055085 L21SP4_RS03845 95ce2f7b906d8bc54990458803ed6fac 244 PANTHER PTHR24220 9 239 1.1E-128 T 22-04-2016 L21SP4_RS03845 95ce2f7b906d8bc54990458803ed6fac 244 Gene3D G3DSA:3.40.50.300 4 235 2.4E-69 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS03845 95ce2f7b906d8bc54990458803ed6fac 244 PANTHER PTHR24220:SF497 9 239 1.1E-128 T 22-04-2016 L21SP4_RS03845 95ce2f7b906d8bc54990458803ed6fac 244 SUPERFAMILY SSF52540 6 238 1.1E-64 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS09135 9c9f372d5bfc6939b0d663520f3da768 307 SUPERFAMILY SSF102114 25 216 1.18E-25 T 22-04-2016 L21SP4_RS09135 9c9f372d5bfc6939b0d663520f3da768 307 Gene3D G3DSA:3.20.20.70 23 212 5.3E-21 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP4_RS09135 9c9f372d5bfc6939b0d663520f3da768 307 Pfam PF04055 Radical SAM superfamily 27 184 1.1E-13 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 L21SP4_RS09135 9c9f372d5bfc6939b0d663520f3da768 307 PANTHER PTHR11228 8 231 4.3E-46 T 22-04-2016 L21SP4_RS09135 9c9f372d5bfc6939b0d663520f3da768 307 PANTHER PTHR11228:SF25 8 231 4.3E-46 T 22-04-2016 L21SP4_RS11890 6972f5f879eb83ed86c4ac741da64928 196 Pfam PF01330 RuvA N terminal domain 1 62 7.2E-20 T 22-04-2016 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 L21SP4_RS11890 6972f5f879eb83ed86c4ac741da64928 196 SUPERFAMILY SSF46929 151 195 1.18E-7 T 22-04-2016 IPR011114 DNA helicase, Holliday junction RuvA type, domain III, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 L21SP4_RS11890 6972f5f879eb83ed86c4ac741da64928 196 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 194 8.4E-48 T 22-04-2016 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 L21SP4_RS11890 6972f5f879eb83ed86c4ac741da64928 196 SUPERFAMILY SSF50249 1 63 4.85E-16 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold L21SP4_RS11890 6972f5f879eb83ed86c4ac741da64928 196 Gene3D G3DSA:1.10.8.10 152 194 5.8E-12 T 22-04-2016 L21SP4_RS11890 6972f5f879eb83ed86c4ac741da64928 196 Pfam PF14520 Helix-hairpin-helix domain 72 130 1.1E-15 T 22-04-2016 L21SP4_RS11890 6972f5f879eb83ed86c4ac741da64928 196 Gene3D G3DSA:1.10.150.20 67 136 4.0E-26 T 22-04-2016 L21SP4_RS11890 6972f5f879eb83ed86c4ac741da64928 196 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 194 28.07 T 22-04-2016 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 L21SP4_RS11890 6972f5f879eb83ed86c4ac741da64928 196 Pfam PF07499 RuvA, C-terminal domain 152 195 3.5E-11 T 22-04-2016 IPR011114 DNA helicase, Holliday junction RuvA type, domain III, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 L21SP4_RS11890 6972f5f879eb83ed86c4ac741da64928 196 SUPERFAMILY SSF47781 65 133 7.56E-19 T 22-04-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 L21SP4_RS11890 6972f5f879eb83ed86c4ac741da64928 196 Gene3D G3DSA:2.40.50.140 1 66 7.1E-24 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold L21SP4_RS11890 6972f5f879eb83ed86c4ac741da64928 196 SMART SM00278 108 127 3.9 T 22-04-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 L21SP4_RS11890 6972f5f879eb83ed86c4ac741da64928 196 SMART SM00278 73 92 13.0 T 22-04-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 L21SP4_RS11890 6972f5f879eb83ed86c4ac741da64928 196 PANTHER PTHR33796 2 194 1.2E-71 T 22-04-2016 L21SP4_RS06965 3faba761caace1b5316c70c68bbcf09e 1044 PANTHER PTHR22600 107 379 6.8E-25 T 22-04-2016 L21SP4_RS06965 3faba761caace1b5316c70c68bbcf09e 1044 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 26 157 2.7E-15 T 22-04-2016 IPR015882 Beta-hexosaminidase, bacteial type, N-terminal KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 L21SP4_RS06965 3faba761caace1b5316c70c68bbcf09e 1044 PANTHER PTHR22600:SF0 107 379 6.8E-25 T 22-04-2016 L21SP4_RS06965 3faba761caace1b5316c70c68bbcf09e 1044 Gene3D G3DSA:3.20.20.80 146 467 2.6E-39 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP4_RS06965 3faba761caace1b5316c70c68bbcf09e 1044 PRINTS PR00738 Glycosyl hydrolase family 20 signature 154 171 3.4E-8 T 22-04-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 L21SP4_RS06965 3faba761caace1b5316c70c68bbcf09e 1044 PRINTS PR00738 Glycosyl hydrolase family 20 signature 229 246 3.4E-8 T 22-04-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 L21SP4_RS06965 3faba761caace1b5316c70c68bbcf09e 1044 PRINTS PR00738 Glycosyl hydrolase family 20 signature 119 139 3.4E-8 T 22-04-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 L21SP4_RS06965 3faba761caace1b5316c70c68bbcf09e 1044 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 212 392 7.6E-11 T 22-04-2016 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 L21SP4_RS06965 3faba761caace1b5316c70c68bbcf09e 1044 Gene3D G3DSA:3.30.379.10 5 145 5.2E-20 T 22-04-2016 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like L21SP4_RS06965 3faba761caace1b5316c70c68bbcf09e 1044 SUPERFAMILY SSF51445 161 458 3.31E-54 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily L21SP4_RS06965 3faba761caace1b5316c70c68bbcf09e 1044 SUPERFAMILY SSF55545 25 158 8.22E-17 T 22-04-2016 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like L21SP4_RS10435 dfcfb4af1c39b9c98172d833100fb56e 825 Gene3D G3DSA:3.40.50.2000 602 786 5.0E-30 T 22-04-2016 L21SP4_RS10435 dfcfb4af1c39b9c98172d833100fb56e 825 PANTHER PTHR12526:SF363 436 804 6.3E-73 T 22-04-2016 L21SP4_RS10435 dfcfb4af1c39b9c98172d833100fb56e 825 PANTHER PTHR12526 436 804 6.3E-73 T 22-04-2016 L21SP4_RS10435 dfcfb4af1c39b9c98172d833100fb56e 825 SUPERFAMILY SSF89550 9 162 5.89E-18 T 22-04-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 L21SP4_RS10435 dfcfb4af1c39b9c98172d833100fb56e 825 SUPERFAMILY SSF89550 191 239 5.89E-18 T 22-04-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 L21SP4_RS10435 dfcfb4af1c39b9c98172d833100fb56e 825 SUPERFAMILY SSF53756 442 801 3.24E-74 T 22-04-2016 L21SP4_RS10435 dfcfb4af1c39b9c98172d833100fb56e 825 Pfam PF00534 Glycosyl transferases group 1 634 783 6.7E-32 T 22-04-2016 IPR001296 Glycosyl transferase, family 1 L21SP4_RS10435 dfcfb4af1c39b9c98172d833100fb56e 825 Pfam PF13439 Glycosyltransferase Family 4 447 616 5.4E-18 T 22-04-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain L21SP4_RS08110 e6cfa8b7b86fe05101a7afdb609847ff 429 Gene3D G3DSA:1.10.150.20 172 232 2.1E-10 T 22-04-2016 L21SP4_RS08110 e6cfa8b7b86fe05101a7afdb609847ff 429 Gene3D G3DSA:3.30.70.270 68 165 3.9E-27 T 22-04-2016 L21SP4_RS08110 e6cfa8b7b86fe05101a7afdb609847ff 429 SUPERFAMILY SSF100879 245 336 3.92E-7 T 22-04-2016 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 L21SP4_RS08110 e6cfa8b7b86fe05101a7afdb609847ff 429 Pfam PF11799 impB/mucB/samB family C-terminal domain 241 352 2.8E-9 T 22-04-2016 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 L21SP4_RS08110 e6cfa8b7b86fe05101a7afdb609847ff 429 Gene3D G3DSA:3.30.1490.100 247 351 6.8E-8 T 22-04-2016 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 L21SP4_RS08110 e6cfa8b7b86fe05101a7afdb609847ff 429 Pfam PF00817 impB/mucB/samB family 12 157 3.7E-45 T 22-04-2016 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 L21SP4_RS08110 e6cfa8b7b86fe05101a7afdb609847ff 429 SUPERFAMILY SSF56672 7 237 4.63E-66 T 22-04-2016 L21SP4_RS08110 e6cfa8b7b86fe05101a7afdb609847ff 429 PANTHER PTHR11076 4 336 2.8E-75 T 22-04-2016 L21SP4_RS05695 7bb750c63e16078a84d4f71ad84072e1 327 PANTHER PTHR30578 13 324 5.0E-75 T 22-04-2016 L21SP4_RS05695 7bb750c63e16078a84d4f71ad84072e1 327 Hamap MF_00462 Electron transport complex subunit RsxD [rsxD]. 16 325 22.394 T 22-04-2016 IPR011303 Electron transport complex, subunit RnfD/RsxD GO:0016021|GO:0022900 L21SP4_RS05695 7bb750c63e16078a84d4f71ad84072e1 327 TIGRFAM TIGR01946 rnfD: electron transport complex, RnfABCDGE type, D subunit 28 323 1.5E-79 T 22-04-2016 IPR011303 Electron transport complex, subunit RnfD/RsxD GO:0016021|GO:0022900 L21SP4_RS05695 7bb750c63e16078a84d4f71ad84072e1 327 Pfam PF03116 NQR2, RnfD, RnfE family 19 323 8.8E-98 T 22-04-2016 IPR004338 NADH-quinone reductase NQR2/RnfD GO:0006810|GO:0016020 L21SP4_RS10475 5cf646964ab0f4a9510b5851e971df88 259 SUPERFAMILY SSF55781 82 250 9.81E-39 T 22-04-2016 IPR029016 GAF domain-like L21SP4_RS10475 5cf646964ab0f4a9510b5851e971df88 259 Gene3D G3DSA:1.10.10.10 5 70 5.3E-14 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS10475 5cf646964ab0f4a9510b5851e971df88 259 Gene3D G3DSA:3.30.450.40 81 251 2.0E-42 T 22-04-2016 IPR029016 GAF domain-like L21SP4_RS10475 5cf646964ab0f4a9510b5851e971df88 259 SMART SM00346 4 96 3.5E-5 T 22-04-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 L21SP4_RS10475 5cf646964ab0f4a9510b5851e971df88 259 SUPERFAMILY SSF46785 5 70 3.31E-11 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS10475 5cf646964ab0f4a9510b5851e971df88 259 PANTHER PTHR30136 2 252 8.8E-46 T 22-04-2016 L21SP4_RS10475 5cf646964ab0f4a9510b5851e971df88 259 Pfam PF01614 Bacterial transcriptional regulator 133 247 2.0E-25 T 22-04-2016 IPR014757 Transcription regulator IclR, C-terminal L21SP4_RS10475 5cf646964ab0f4a9510b5851e971df88 259 Pfam PF09339 IclR helix-turn-helix domain 9 56 3.3E-11 T 22-04-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 L21SP4_RS03410 85286305131503a626f4f8b9f6c197b1 153 Pfam PF06841 T4-like virus tail tube protein gp19 13 153 6.9E-27 T 22-04-2016 IPR010667 Bacteriophage T4, Gp19, tail tube GO:0005198 L21SP4_RS03410 85286305131503a626f4f8b9f6c197b1 153 ProDom PD034665 TAIL TUBE GP19 MONOMER STRUCTURAL GP19-LIKE GP19V GP54 SEQUENCING DIRECT 53 152 0.002 T 22-04-2016 L21SP4_RS11660 fbdfc2af99322a72e6e39c33ff2f35eb 99 Pfam PF12840 Helix-turn-helix domain 12 70 2.7E-14 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS11660 fbdfc2af99322a72e6e39c33ff2f35eb 99 SUPERFAMILY SSF46785 4 94 5.01E-22 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS11660 fbdfc2af99322a72e6e39c33ff2f35eb 99 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 62 77 3.3E-6 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 L21SP4_RS11660 fbdfc2af99322a72e6e39c33ff2f35eb 99 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 15 30 3.3E-6 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 L21SP4_RS11660 fbdfc2af99322a72e6e39c33ff2f35eb 99 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 47 62 3.3E-6 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 L21SP4_RS11660 fbdfc2af99322a72e6e39c33ff2f35eb 99 Gene3D G3DSA:1.10.10.10 3 95 3.6E-26 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS11660 fbdfc2af99322a72e6e39c33ff2f35eb 99 PANTHER PTHR33154 1 93 3.3E-24 T 22-04-2016 L21SP4_RS11660 fbdfc2af99322a72e6e39c33ff2f35eb 99 SMART SM00418 13 91 1.2E-16 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 L21SP4_RS10140 0066aa8af7ab916df7cff1f7dfd085bb 195 PANTHER PTHR11649 1 40 1.3E-31 T 22-04-2016 L21SP4_RS10140 0066aa8af7ab916df7cff1f7dfd085bb 195 PANTHER PTHR11649:SF37 1 40 1.3E-31 T 22-04-2016 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 L21SP4_RS10140 0066aa8af7ab916df7cff1f7dfd085bb 195 PANTHER PTHR11649:SF37 96 163 1.3E-31 T 22-04-2016 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 L21SP4_RS10140 0066aa8af7ab916df7cff1f7dfd085bb 195 PANTHER PTHR11649 96 163 1.3E-31 T 22-04-2016 L21SP4_RS10140 0066aa8af7ab916df7cff1f7dfd085bb 195 Pfam PF07670 Nucleoside recognition 1 128 1.9E-17 T 22-04-2016 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: REACT_15518|Reactome: REACT_1698 L21SP4_RS03855 d00699e1ef4917a7361a5da8aa05adf7 312 SUPERFAMILY SSF53795 136 299 1.89E-28 T 22-04-2016 L21SP4_RS03855 d00699e1ef4917a7361a5da8aa05adf7 312 Gene3D G3DSA:3.40.1390.20 10 130 3.1E-32 T 22-04-2016 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like L21SP4_RS03855 d00699e1ef4917a7361a5da8aa05adf7 312 TIGRFAM TIGR00679 hpr-ser: HPr(Ser) kinase/phosphatase 4 303 7.7E-88 T 22-04-2016 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 L21SP4_RS03855 d00699e1ef4917a7361a5da8aa05adf7 312 PANTHER PTHR30305 1 312 6.2E-91 T 22-04-2016 L21SP4_RS03855 d00699e1ef4917a7361a5da8aa05adf7 312 Pfam PF07475 HPr Serine kinase C-terminal domain 135 301 5.6E-50 T 22-04-2016 IPR011104 HPr kinase/phosphorylase, C-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 L21SP4_RS03855 d00699e1ef4917a7361a5da8aa05adf7 312 SUPERFAMILY SSF75138 8 131 2.49E-29 T 22-04-2016 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like L21SP4_RS03855 d00699e1ef4917a7361a5da8aa05adf7 312 Gene3D G3DSA:3.40.50.300 137 308 1.6E-53 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS03855 d00699e1ef4917a7361a5da8aa05adf7 312 PANTHER PTHR30305:SF1 1 312 6.2E-91 T 22-04-2016 L21SP4_RS03855 d00699e1ef4917a7361a5da8aa05adf7 312 Pfam PF02603 HPr Serine kinase N terminus 4 127 6.9E-32 T 22-04-2016 IPR011126 HPr(Ser) kinase/phosphorylase, N-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 L21SP4_RS10870 d0fcc42cac4470455424a36aa8f803ac 265 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 1 247 8.4E-43 T 22-04-2016 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 L21SP4_RS10870 d0fcc42cac4470455424a36aa8f803ac 265 PANTHER PTHR13799 1 261 9.4E-83 T 22-04-2016 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 L21SP4_RS10870 d0fcc42cac4470455424a36aa8f803ac 265 PANTHER PTHR13799:SF13 1 261 9.4E-83 T 22-04-2016 L21SP4_RS10870 d0fcc42cac4470455424a36aa8f803ac 265 SUPERFAMILY SSF102705 1 257 1.12E-67 T 22-04-2016 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 L21SP4_RS10870 d0fcc42cac4470455424a36aa8f803ac 265 Gene3D G3DSA:3.40.1390.30 1 114 1.0E-40 T 22-04-2016 L21SP4_RS10870 d0fcc42cac4470455424a36aa8f803ac 265 Gene3D G3DSA:3.40.1390.30 115 222 7.1E-25 T 22-04-2016 L21SP4_RS10870 d0fcc42cac4470455424a36aa8f803ac 265 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 6 242 2.2E-65 T 22-04-2016 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 L21SP4_RS04560 e983cd79af0c3fddb71defc560e0f599 587 Gene3D G3DSA:3.30.1120.10 357 423 2.1E-9 T 22-04-2016 L21SP4_RS04560 e983cd79af0c3fddb71defc560e0f599 587 SUPERFAMILY SSF53649 23 420 2.47E-109 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS04560 e983cd79af0c3fddb71defc560e0f599 587 Gene3D G3DSA:3.40.720.10 22 353 9.1E-99 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS04560 e983cd79af0c3fddb71defc560e0f599 587 Pfam PF00884 Sulfatase 25 332 2.1E-57 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS04560 e983cd79af0c3fddb71defc560e0f599 587 PANTHER PTHR10342 1 421 1.7E-120 T 22-04-2016 L21SP4_RS04560 e983cd79af0c3fddb71defc560e0f599 587 PANTHER PTHR10342:SF199 1 421 1.7E-120 T 22-04-2016 L21SP4_RS04305 8db15a0b9f9040655f34780530b56c82 74 PANTHER PTHR34849 1 74 1.1E-22 T 22-04-2016 L21SP4_RS04305 8db15a0b9f9040655f34780530b56c82 74 SUPERFAMILY SSF46689 3 66 4.66E-20 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS04305 8db15a0b9f9040655f34780530b56c82 74 Gene3D G3DSA:1.10.10.10 7 67 4.3E-24 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS04305 8db15a0b9f9040655f34780530b56c82 74 PANTHER PTHR34849:SF2 1 74 1.1E-22 T 22-04-2016 L21SP4_RS04305 8db15a0b9f9040655f34780530b56c82 74 Pfam PF04255 Protein of unknown function (DUF433) 8 63 2.8E-23 T 22-04-2016 IPR007367 Protein of unknown function DUF433 L21SP4_RS04605 cfc948f1a90611727de664a77f789402 752 Gene3D G3DSA:2.160.20.10 394 469 6.1E-16 T 22-04-2016 IPR012334 Pectin lyase fold L21SP4_RS04605 cfc948f1a90611727de664a77f789402 752 Gene3D G3DSA:2.160.20.10 29 288 4.0E-11 T 22-04-2016 IPR012334 Pectin lyase fold L21SP4_RS04605 cfc948f1a90611727de664a77f789402 752 Gene3D G3DSA:2.160.20.10 599 675 6.1E-16 T 22-04-2016 IPR012334 Pectin lyase fold L21SP4_RS04605 cfc948f1a90611727de664a77f789402 752 SUPERFAMILY SSF51126 393 469 6.02E-13 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor L21SP4_RS04605 cfc948f1a90611727de664a77f789402 752 SUPERFAMILY SSF51126 30 266 4.35E-9 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor L21SP4_RS04605 cfc948f1a90611727de664a77f789402 752 Pfam PF12708 Pectate lyase superfamily protein 402 465 1.6E-13 T 22-04-2016 IPR024535 Pectate lyase superfamily protein L21SP4_RS04605 cfc948f1a90611727de664a77f789402 752 Pfam PF12708 Pectate lyase superfamily protein 29 265 2.0E-8 T 22-04-2016 IPR024535 Pectate lyase superfamily protein L21SP4_RS10490 8c4fd7873337cf167804b75d12b87680 639 SUPERFAMILY SSF49899 39 271 9.29E-17 T 22-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP4_RS10490 8c4fd7873337cf167804b75d12b87680 639 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 117 269 1.3E-10 T 22-04-2016 L21SP4_RS10490 8c4fd7873337cf167804b75d12b87680 639 SUPERFAMILY SSF51126 275 625 1.14E-26 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor L21SP4_RS10490 8c4fd7873337cf167804b75d12b87680 639 Gene3D G3DSA:2.60.120.200 40 271 9.0E-15 T 22-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP4_RS10490 8c4fd7873337cf167804b75d12b87680 639 Pfam PF12708 Pectate lyase superfamily protein 286 362 7.2E-11 T 22-04-2016 IPR024535 Pectate lyase superfamily protein L21SP4_RS10490 8c4fd7873337cf167804b75d12b87680 639 Gene3D G3DSA:2.160.20.10 275 554 1.3E-23 T 22-04-2016 IPR012334 Pectin lyase fold L21SP4_RS09555 20161c2af1d5a0d5b62a8c8a2225dd4c 192 SUPERFAMILY SSF55021 102 181 2.06E-14 T 22-04-2016 L21SP4_RS09555 20161c2af1d5a0d5b62a8c8a2225dd4c 192 PANTHER PTHR34875 1 190 1.1E-19 T 22-04-2016 L21SP4_RS09555 20161c2af1d5a0d5b62a8c8a2225dd4c 192 Pfam PF13740 ACT domain 6 75 1.5E-8 T 22-04-2016 L21SP4_RS09555 20161c2af1d5a0d5b62a8c8a2225dd4c 192 Pfam PF13740 ACT domain 103 175 2.4E-10 T 22-04-2016 L21SP4_RS09555 20161c2af1d5a0d5b62a8c8a2225dd4c 192 Gene3D G3DSA:3.30.70.260 101 186 4.1E-22 T 22-04-2016 L21SP4_RS09555 20161c2af1d5a0d5b62a8c8a2225dd4c 192 SUPERFAMILY SSF55021 6 75 1.59E-13 T 22-04-2016 L21SP4_RS09555 20161c2af1d5a0d5b62a8c8a2225dd4c 192 Gene3D G3DSA:3.30.70.260 5 75 4.8E-18 T 22-04-2016 L21SP4_RS08185 01e40f8affc6718c6c65b01614afcb7d 325 PANTHER PTHR30349 12 285 4.4E-50 T 22-04-2016 L21SP4_RS08185 01e40f8affc6718c6c65b01614afcb7d 325 SUPERFAMILY SSF53850 118 284 5.97E-9 T 22-04-2016 L21SP4_RS08185 01e40f8affc6718c6c65b01614afcb7d 325 PANTHER PTHR30349:SF1 12 285 4.4E-50 T 22-04-2016 L21SP4_RS08185 01e40f8affc6718c6c65b01614afcb7d 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 55 322 6.4E-44 T 22-04-2016 IPR005064 Bordetella uptake gene GO:0030288 L21SP4_RS08185 01e40f8affc6718c6c65b01614afcb7d 325 PIRSF PIRSF017082 1 325 4.0E-89 T 22-04-2016 IPR005064 Bordetella uptake gene GO:0030288 L21SP4_RS01560 f6605b23c04057e0407cf4e205b77160 1333 PANTHER PTHR22925:SF40 336 534 4.2E-45 T 22-04-2016 L21SP4_RS01560 f6605b23c04057e0407cf4e205b77160 1333 PANTHER PTHR22925:SF40 198 208 4.2E-45 T 22-04-2016 L21SP4_RS01560 f6605b23c04057e0407cf4e205b77160 1333 PANTHER PTHR22925:SF40 313 318 4.2E-45 T 22-04-2016 L21SP4_RS01560 f6605b23c04057e0407cf4e205b77160 1333 PANTHER PTHR22925:SF40 285 294 4.2E-45 T 22-04-2016 L21SP4_RS01560 f6605b23c04057e0407cf4e205b77160 1333 PANTHER PTHR22925:SF40 35 176 4.2E-45 T 22-04-2016 L21SP4_RS01560 f6605b23c04057e0407cf4e205b77160 1333 Gene3D G3DSA:2.60.120.260 1139 1263 4.4E-13 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS01560 f6605b23c04057e0407cf4e205b77160 1333 SUPERFAMILY SSF49899 929 1086 1.58E-7 T 22-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP4_RS01560 f6605b23c04057e0407cf4e205b77160 1333 PANTHER PTHR22925 336 534 4.2E-45 T 22-04-2016 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 L21SP4_RS01560 f6605b23c04057e0407cf4e205b77160 1333 PANTHER PTHR22925 198 208 4.2E-45 T 22-04-2016 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 L21SP4_RS01560 f6605b23c04057e0407cf4e205b77160 1333 PANTHER PTHR22925 313 318 4.2E-45 T 22-04-2016 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 L21SP4_RS01560 f6605b23c04057e0407cf4e205b77160 1333 PANTHER PTHR22925 285 294 4.2E-45 T 22-04-2016 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 L21SP4_RS01560 f6605b23c04057e0407cf4e205b77160 1333 PANTHER PTHR22925 35 176 4.2E-45 T 22-04-2016 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 L21SP4_RS01560 f6605b23c04057e0407cf4e205b77160 1333 Pfam PF17132 alpha-L-rhamnosidase 29 861 1.6E-212 T 22-04-2016 IPR033400 Alpha-L-rhamnosidase RhaM L21SP4_RS01560 f6605b23c04057e0407cf4e205b77160 1333 SUPERFAMILY SSF49785 1138 1268 7.31E-19 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS01560 f6605b23c04057e0407cf4e205b77160 1333 Gene3D G3DSA:2.60.120.200 925 1041 5.1E-4 T 22-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP4_RS02865 f66b01546e3e823bcea543fc37c2651e 453 Pfam PF11973 NQRA C-terminal domain 266 314 4.8E-8 T 22-04-2016 IPR022615 Na(+)-translocating NADH-quinone reductase subunit A, C-terminal domain GO:0016655|GO:0055114 L21SP4_RS02865 f66b01546e3e823bcea543fc37c2651e 453 Pfam PF05896 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) 5 261 1.3E-69 T 22-04-2016 IPR008703 Na(+)-translocating NADH-quinone reductase subunit A GO:0006814|GO:0016655|GO:0055114 L21SP4_RS02865 f66b01546e3e823bcea543fc37c2651e 453 Hamap MF_00425 Na(+)-translocating NADH-quinone reductase subunit A [nqrA]. 3 452 34.939 T 22-04-2016 IPR008703 Na(+)-translocating NADH-quinone reductase subunit A GO:0006814|GO:0016655|GO:0055114 L21SP4_RS02865 f66b01546e3e823bcea543fc37c2651e 453 TIGRFAM TIGR01936 nqrA: NADH:ubiquinone oxidoreductase, Na(+)-translocating, A subunit 6 452 2.0E-111 T 22-04-2016 IPR008703 Na(+)-translocating NADH-quinone reductase subunit A GO:0006814|GO:0016655|GO:0055114 L21SP4_RS02865 f66b01546e3e823bcea543fc37c2651e 453 PANTHER PTHR37839 1 453 2.5E-119 T 22-04-2016 L21SP4_RS02865 f66b01546e3e823bcea543fc37c2651e 453 PANTHER PTHR37839:SF1 1 453 2.5E-119 T 22-04-2016 L21SP4_RS03695 e51a38dae0a85ba3ad0d433d190342b4 398 TIGRFAM TIGR04258 4helix_suffix: four helix bundle suffix domain 350 396 6.2E-18 T 22-04-2016 IPR026354 Four helix bundle suffix domain L21SP4_RS03695 e51a38dae0a85ba3ad0d433d190342b4 398 Gene3D G3DSA:1.20.1440.60 16 86 1.0E-4 T 22-04-2016 IPR012657 23S rRNA-intervening sequence protein L21SP4_RS03695 e51a38dae0a85ba3ad0d433d190342b4 398 SUPERFAMILY SSF158446 11 101 5.1E-14 T 22-04-2016 L21SP4_RS03695 e51a38dae0a85ba3ad0d433d190342b4 398 Pfam PF05635 23S rRNA-intervening sequence protein 16 86 3.1E-5 T 22-04-2016 IPR012657 23S rRNA-intervening sequence protein L21SP4_RS03695 e51a38dae0a85ba3ad0d433d190342b4 398 TIGRFAM TIGR02436 TIGR02436: four helix bundle protein 16 86 2.2E-7 T 22-04-2016 IPR012657 23S rRNA-intervening sequence protein L21SP4_RS11235 66a9be01eef53fc72296c5408ad09eb9 222 Pfam PF03567 Sulfotransferase family 52 141 4.1E-5 T 22-04-2016 IPR005331 Sulfotransferase GO:0008146|GO:0016021 L21SP4_RS04935 7058661ce9fa756c0543d793b813f60e 325 PIRSF PIRSF002849 1 325 1.3E-132 T 22-04-2016 IPR016366 ATPase chaperone, AAA-type, MoxR, predicted L21SP4_RS04935 7058661ce9fa756c0543d793b813f60e 325 PANTHER PTHR11603 10 322 1.7E-135 T 22-04-2016 L21SP4_RS04935 7058661ce9fa756c0543d793b813f60e 325 SUPERFAMILY SSF52540 11 296 8.1E-47 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS04935 7058661ce9fa756c0543d793b813f60e 325 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 42 171 1.6E-65 T 22-04-2016 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 L21SP4_RS04935 7058661ce9fa756c0543d793b813f60e 325 Gene3D G3DSA:3.40.50.300 23 189 6.1E-46 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS04935 7058661ce9fa756c0543d793b813f60e 325 PANTHER PTHR11603:SF148 10 322 1.7E-135 T 22-04-2016 L21SP4_RS04935 7058661ce9fa756c0543d793b813f60e 325 Gene3D G3DSA:1.10.8.300 203 320 1.3E-37 T 22-04-2016 L21SP4_RS00650 8b350d20cd2c67feda5f38ed866ef45c 452 ProSitePatterns PS00216 Sugar transport proteins signature 1. 61 78 - T 22-04-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 L21SP4_RS00650 8b350d20cd2c67feda5f38ed866ef45c 452 ProSitePatterns PS00216 Sugar transport proteins signature 1. 304 321 - T 22-04-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 L21SP4_RS00650 8b350d20cd2c67feda5f38ed866ef45c 452 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 3 446 1.9E-124 T 22-04-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 L21SP4_RS00650 8b350d20cd2c67feda5f38ed866ef45c 452 SUPERFAMILY SSF103473 6 447 9.02E-75 T 22-04-2016 IPR020846 Major facilitator superfamily domain L21SP4_RS00650 8b350d20cd2c67feda5f38ed866ef45c 452 PANTHER PTHR23500 3 450 2.8E-190 T 22-04-2016 L21SP4_RS00650 8b350d20cd2c67feda5f38ed866ef45c 452 PRINTS PR00171 Sugar transporter signature 15 25 1.1E-28 T 22-04-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 L21SP4_RS00650 8b350d20cd2c67feda5f38ed866ef45c 452 PRINTS PR00171 Sugar transporter signature 345 366 1.1E-28 T 22-04-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 L21SP4_RS00650 8b350d20cd2c67feda5f38ed866ef45c 452 PRINTS PR00171 Sugar transporter signature 368 380 1.1E-28 T 22-04-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 L21SP4_RS00650 8b350d20cd2c67feda5f38ed866ef45c 452 PRINTS PR00171 Sugar transporter signature 260 270 1.1E-28 T 22-04-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 L21SP4_RS00650 8b350d20cd2c67feda5f38ed866ef45c 452 PRINTS PR00171 Sugar transporter signature 98 117 1.1E-28 T 22-04-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 L21SP4_RS00650 8b350d20cd2c67feda5f38ed866ef45c 452 Gene3D G3DSA:1.20.1250.20 252 447 1.3E-24 T 22-04-2016 L21SP4_RS00650 8b350d20cd2c67feda5f38ed866ef45c 452 Gene3D G3DSA:1.20.1250.20 10 197 1.0E-26 T 22-04-2016 L21SP4_RS00650 8b350d20cd2c67feda5f38ed866ef45c 452 ProSitePatterns PS00217 Sugar transport proteins signature 2. 103 128 - T 22-04-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 L21SP4_RS00650 8b350d20cd2c67feda5f38ed866ef45c 452 PANTHER PTHR23500:SF22 3 450 2.8E-190 T 22-04-2016 L21SP4_RS00650 8b350d20cd2c67feda5f38ed866ef45c 452 Pfam PF00083 Sugar (and other) transporter 8 450 1.5E-125 T 22-04-2016 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 L21SP4_RS09300 948c46ffdbf85d9509eedbf990a0471c 240 PANTHER PTHR34857:SF2 14 239 6.6E-33 T 22-04-2016 L21SP4_RS09300 948c46ffdbf85d9509eedbf990a0471c 240 Pfam PF02361 Cobalt transport protein 15 203 9.7E-14 T 22-04-2016 IPR003339 ABC/ECF transporter, transmembrane component L21SP4_RS09300 948c46ffdbf85d9509eedbf990a0471c 240 PANTHER PTHR34857 14 239 6.6E-33 T 22-04-2016 L21SP4_RS04045 3592fe3606e72206f22121dcf2c23796 419 Pfam PF00923 Transaldolase 44 319 1.5E-34 T 22-04-2016 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 L21SP4_RS04045 3592fe3606e72206f22121dcf2c23796 419 PANTHER PTHR10683 19 311 1.3E-25 T 22-04-2016 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 L21SP4_RS04045 3592fe3606e72206f22121dcf2c23796 419 Gene3D G3DSA:3.20.20.70 35 320 1.1E-42 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP4_RS04045 3592fe3606e72206f22121dcf2c23796 419 SUPERFAMILY SSF51569 36 328 3.42E-39 T 22-04-2016 L21SP4_RS08195 9eb50729b7f4e316bc126764a081b407 298 Pfam PF01261 Xylose isomerase-like TIM barrel 51 236 5.2E-11 T 22-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain L21SP4_RS08195 9eb50729b7f4e316bc126764a081b407 298 Gene3D G3DSA:3.20.20.150 24 290 1.1E-21 T 22-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain L21SP4_RS08195 9eb50729b7f4e316bc126764a081b407 298 SUPERFAMILY SSF51658 46 289 1.26E-22 T 22-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain L21SP4_RS03120 087ae0e49207c71ed0c99a258fdd73e8 185 PANTHER PTHR23416:SF52 21 183 2.5E-38 T 22-04-2016 L21SP4_RS03120 087ae0e49207c71ed0c99a258fdd73e8 185 SUPERFAMILY SSF51161 15 175 6.93E-38 T 22-04-2016 IPR011004 Trimeric LpxA-like L21SP4_RS03120 087ae0e49207c71ed0c99a258fdd73e8 185 Gene3D G3DSA:2.160.10.10 23 177 1.6E-41 T 22-04-2016 L21SP4_RS03120 087ae0e49207c71ed0c99a258fdd73e8 185 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 131 159 - T 22-04-2016 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: REACT_17015 L21SP4_RS03120 087ae0e49207c71ed0c99a258fdd73e8 185 PANTHER PTHR23416 21 183 2.5E-38 T 22-04-2016 L21SP4_RS03120 087ae0e49207c71ed0c99a258fdd73e8 185 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 122 157 5.7E-9 T 22-04-2016 IPR001451 Hexapeptide repeat L21SP4_RS00965 945486fef369e47bf9373f9a4aefe8a8 361 SUPERFAMILY SSF53756 7 353 5.02E-82 T 22-04-2016 L21SP4_RS00965 945486fef369e47bf9373f9a4aefe8a8 361 Pfam PF00534 Glycosyl transferases group 1 172 327 2.1E-33 T 22-04-2016 IPR001296 Glycosyl transferase, family 1 L21SP4_RS00965 945486fef369e47bf9373f9a4aefe8a8 361 Pfam PF13439 Glycosyltransferase Family 4 26 156 1.1E-11 T 22-04-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain L21SP4_RS00965 945486fef369e47bf9373f9a4aefe8a8 361 PANTHER PTHR12526 4 351 4.9E-67 T 22-04-2016 L21SP4_RS00965 945486fef369e47bf9373f9a4aefe8a8 361 Gene3D G3DSA:3.40.50.2000 138 327 1.4E-32 T 22-04-2016 L21SP4_RS04455 3e8da0d58c25ef8ba0d51d04712a0c89 410 Gene3D G3DSA:3.90.350.10 291 321 6.2E-5 T 22-04-2016 IPR014736 Transposase, Tn5-like, core L21SP4_RS04455 3e8da0d58c25ef8ba0d51d04712a0c89 410 Pfam PF01609 Transposase DDE domain 130 346 3.8E-21 T 22-04-2016 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 L21SP4_RS04455 3e8da0d58c25ef8ba0d51d04712a0c89 410 PANTHER PTHR33258:SF1 8 382 9.0E-32 T 22-04-2016 L21SP4_RS04455 3e8da0d58c25ef8ba0d51d04712a0c89 410 PANTHER PTHR33258 8 382 9.0E-32 T 22-04-2016 L21SP4_RS04455 3e8da0d58c25ef8ba0d51d04712a0c89 410 Pfam PF14294 Domain of unknown function (DUF4372) 10 71 1.5E-11 T 22-04-2016 IPR025399 Domain of unknown function DUF4372 L21SP4_RS04455 3e8da0d58c25ef8ba0d51d04712a0c89 410 SUPERFAMILY SSF53098 128 367 1.9E-20 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS05820 40f450d774cd77953cb646f1a2677d3c 312 SUPERFAMILY SSF56300 85 308 4.98E-32 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like L21SP4_RS05820 40f450d774cd77953cb646f1a2677d3c 312 Gene3D G3DSA:3.60.21.10 89 255 7.6E-20 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like L21SP4_RS05820 40f450d774cd77953cb646f1a2677d3c 312 PANTHER PTHR31302 1 312 3.0E-46 T 22-04-2016 L21SP4_RS05820 40f450d774cd77953cb646f1a2677d3c 312 Pfam PF00149 Calcineurin-like phosphoesterase 89 247 2.3E-11 T 22-04-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 L21SP4_RS00190 f67f591dea3b9249eb8ce3eb2f4f4249 392 Gene3D G3DSA:3.90.1150.10 256 378 4.3E-48 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 L21SP4_RS00190 f67f591dea3b9249eb8ce3eb2f4f4249 392 Gene3D G3DSA:3.40.640.10 18 255 4.4E-83 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 L21SP4_RS00190 f67f591dea3b9249eb8ce3eb2f4f4249 392 Pfam PF00266 Aminotransferase class-V 6 373 1.1E-83 T 22-04-2016 IPR000192 Aminotransferase class V domain L21SP4_RS00190 f67f591dea3b9249eb8ce3eb2f4f4249 392 PIRSF PIRSF005572 3 388 6.2E-131 T 22-04-2016 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 L21SP4_RS00190 f67f591dea3b9249eb8ce3eb2f4f4249 392 PANTHER PTHR11601:SF20 3 392 8.0E-156 T 22-04-2016 L21SP4_RS00190 f67f591dea3b9249eb8ce3eb2f4f4249 392 SUPERFAMILY SSF53383 6 381 2.89E-110 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase L21SP4_RS00190 f67f591dea3b9249eb8ce3eb2f4f4249 392 PANTHER PTHR11601 3 392 8.0E-156 T 22-04-2016 L21SP4_RS02565 093c44d1aa6d66d05f1b69b82c73ff5a 222 Gene3D G3DSA:3.30.63.10 16 54 3.7E-8 T 22-04-2016 L21SP4_RS02565 093c44d1aa6d66d05f1b69b82c73ff5a 222 SUPERFAMILY SSF52540 6 115 7.3E-11 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS02565 093c44d1aa6d66d05f1b69b82c73ff5a 222 SUPERFAMILY SSF52540 148 181 7.3E-11 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS07210 9c13839948520aae7f97eff2d6dde213 845 SUPERFAMILY SSF48208 438 830 2.55E-45 T 22-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP4_RS07210 9c13839948520aae7f97eff2d6dde213 845 SUPERFAMILY SSF49785 64 147 3.4E-6 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS07210 9c13839948520aae7f97eff2d6dde213 845 PANTHER PTHR34987 40 829 1.0E-43 T 22-04-2016 L21SP4_RS07210 9c13839948520aae7f97eff2d6dde213 845 Gene3D G3DSA:2.60.120.260 64 144 1.9E-5 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS07210 9c13839948520aae7f97eff2d6dde213 845 Pfam PF05592 Bacterial alpha-L-rhamnosidase 307 828 1.2E-55 T 22-04-2016 IPR008902 Bacterial alpha-L-rhamnosidase L21SP4_RS07210 9c13839948520aae7f97eff2d6dde213 845 Pfam PF08531 Alpha-L-rhamnosidase N-terminal domain 117 241 1.2E-6 T 22-04-2016 IPR013737 Bacterial alpha-L-rhamnosidase N-terminal L21SP4_RS07640 38f06fdac0945609d665da6069526d9a 714 PANTHER PTHR10264 418 541 7.1E-20 T 22-04-2016 IPR001972 Stomatin family GO:0016020 L21SP4_RS07640 38f06fdac0945609d665da6069526d9a 714 PANTHER PTHR10264 298 346 7.1E-20 T 22-04-2016 IPR001972 Stomatin family GO:0016020 L21SP4_RS07640 38f06fdac0945609d665da6069526d9a 714 SMART SM00244 312 527 9.5E-6 T 22-04-2016 IPR001107 Band 7 domain L21SP4_RS07640 38f06fdac0945609d665da6069526d9a 714 Pfam PF01145 SPFH domain / Band 7 family 316 543 1.4E-16 T 22-04-2016 IPR001107 Band 7 domain L21SP4_RS07640 38f06fdac0945609d665da6069526d9a 714 SUPERFAMILY SSF117892 432 534 9.94E-8 T 22-04-2016 IPR001107 Band 7 domain L21SP4_RS02825 928e6e1e43446fa0caf8b8b7b1e08659 81 SUPERFAMILY SSF82771 2 69 6.15E-7 T 22-04-2016 IPR000305 GIY-YIG nuclease superfamily L21SP4_RS02825 928e6e1e43446fa0caf8b8b7b1e08659 81 Pfam PF01541 GIY-YIG catalytic domain 2 70 8.5E-14 T 22-04-2016 IPR000305 GIY-YIG nuclease superfamily L21SP4_RS11665 ac467e9792e1c887fa83ab4079e5c120 566 PANTHER PTHR22912:SF140 6 454 1.7E-136 T 22-04-2016 L21SP4_RS11665 ac467e9792e1c887fa83ab4079e5c120 566 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 344 447 2.6E-16 T 22-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 L21SP4_RS11665 ac467e9792e1c887fa83ab4079e5c120 566 SUPERFAMILY SSF51905 2 304 1.38E-45 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP4_RS11665 ac467e9792e1c887fa83ab4079e5c120 566 SUPERFAMILY SSF55424 337 459 2.06E-27 T 22-04-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 L21SP4_RS11665 ac467e9792e1c887fa83ab4079e5c120 566 Pfam PF00581 Rhodanese-like domain 470 560 7.2E-8 T 22-04-2016 IPR001763 Rhodanese-like domain L21SP4_RS11665 ac467e9792e1c887fa83ab4079e5c120 566 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 163 181 3.6E-26 T 22-04-2016 L21SP4_RS11665 ac467e9792e1c887fa83ab4079e5c120 566 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 248 264 3.6E-26 T 22-04-2016 L21SP4_RS11665 ac467e9792e1c887fa83ab4079e5c120 566 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 275 297 3.6E-26 T 22-04-2016 L21SP4_RS11665 ac467e9792e1c887fa83ab4079e5c120 566 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 3.6E-26 T 22-04-2016 L21SP4_RS11665 ac467e9792e1c887fa83ab4079e5c120 566 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 116 134 3.6E-26 T 22-04-2016 L21SP4_RS11665 ac467e9792e1c887fa83ab4079e5c120 566 Gene3D G3DSA:3.50.50.60 3 124 9.0E-21 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP4_RS11665 ac467e9792e1c887fa83ab4079e5c120 566 Gene3D G3DSA:3.40.250.10 464 560 2.6E-19 T 22-04-2016 IPR001763 Rhodanese-like domain L21SP4_RS11665 ac467e9792e1c887fa83ab4079e5c120 566 SMART SM00450 468 566 2.0E-10 T 22-04-2016 IPR001763 Rhodanese-like domain L21SP4_RS11665 ac467e9792e1c887fa83ab4079e5c120 566 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 163 188 3.3E-13 T 22-04-2016 L21SP4_RS11665 ac467e9792e1c887fa83ab4079e5c120 566 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 3.3E-13 T 22-04-2016 L21SP4_RS11665 ac467e9792e1c887fa83ab4079e5c120 566 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 249 263 3.3E-13 T 22-04-2016 L21SP4_RS11665 ac467e9792e1c887fa83ab4079e5c120 566 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 290 297 3.3E-13 T 22-04-2016 L21SP4_RS11665 ac467e9792e1c887fa83ab4079e5c120 566 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 302 2.5E-60 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP4_RS11665 ac467e9792e1c887fa83ab4079e5c120 566 SUPERFAMILY SSF52821 457 560 2.23E-22 T 22-04-2016 IPR001763 Rhodanese-like domain L21SP4_RS11665 ac467e9792e1c887fa83ab4079e5c120 566 PANTHER PTHR22912 6 454 1.7E-136 T 22-04-2016 L21SP4_RS11665 ac467e9792e1c887fa83ab4079e5c120 566 Gene3D G3DSA:3.30.390.30 349 459 3.4E-31 T 22-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 L21SP4_RS11665 ac467e9792e1c887fa83ab4079e5c120 566 Gene3D G3DSA:3.50.50.60 125 327 2.4E-52 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP4_RS03755 9e534e4b30b4935108bf08006972dcf2 434 PANTHER PTHR30026:SF4 2 423 4.0E-52 T 22-04-2016 L21SP4_RS03755 9e534e4b30b4935108bf08006972dcf2 434 Pfam PF02321 Outer membrane efflux protein 237 422 3.8E-40 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 L21SP4_RS03755 9e534e4b30b4935108bf08006972dcf2 434 Pfam PF02321 Outer membrane efflux protein 29 209 1.5E-22 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 L21SP4_RS03755 9e534e4b30b4935108bf08006972dcf2 434 Gene3D G3DSA:1.20.1600.10 27 422 2.1E-75 T 22-04-2016 L21SP4_RS03755 9e534e4b30b4935108bf08006972dcf2 434 PANTHER PTHR30026 2 423 4.0E-52 T 22-04-2016 L21SP4_RS03755 9e534e4b30b4935108bf08006972dcf2 434 SUPERFAMILY SSF56954 3 423 5.62E-82 T 22-04-2016 L21SP4_RS10410 fa6dbe041677d710adfd7b1d104223ea 670 SUPERFAMILY SSF140990 442 638 4.58E-70 T 22-04-2016 L21SP4_RS10410 fa6dbe041677d710adfd7b1d104223ea 670 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 228 360 9.8E-45 T 22-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 L21SP4_RS10410 fa6dbe041677d710adfd7b1d104223ea 670 Pfam PF01434 Peptidase family M41 422 629 3.4E-77 T 22-04-2016 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 L21SP4_RS10410 fa6dbe041677d710adfd7b1d104223ea 670 Gene3D G3DSA:1.10.8.60 365 444 1.1E-25 T 22-04-2016 L21SP4_RS10410 fa6dbe041677d710adfd7b1d104223ea 670 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 139 631 6.1E-230 T 22-04-2016 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 L21SP4_RS10410 fa6dbe041677d710adfd7b1d104223ea 670 ProSitePatterns PS00674 AAA-protein family signature. 331 349 - T 22-04-2016 IPR003960 ATPase, AAA-type, conserved site GO:0005524 L21SP4_RS10410 fa6dbe041677d710adfd7b1d104223ea 670 PANTHER PTHR23076 36 664 4.3E-289 T 22-04-2016 L21SP4_RS10410 fa6dbe041677d710adfd7b1d104223ea 670 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 28 645 36.622 T 22-04-2016 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 L21SP4_RS10410 fa6dbe041677d710adfd7b1d104223ea 670 SUPERFAMILY SSF52540 184 431 2.99E-72 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS10410 fa6dbe041677d710adfd7b1d104223ea 670 Gene3D G3DSA:3.40.50.300 186 359 5.7E-62 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS10410 fa6dbe041677d710adfd7b1d104223ea 670 SMART SM00382 224 363 1.3E-22 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS10625 e4e27acd814760629db940d6bffd3dae 230 Pfam PF04298 Putative neutral zinc metallopeptidase 8 221 3.6E-81 T 22-04-2016 IPR007395 Putative neutral zinc metallopeptidase L21SP4_RS10625 e4e27acd814760629db940d6bffd3dae 230 PANTHER PTHR36434 1 230 5.3E-92 T 22-04-2016 L21SP4_RS06780 5d978c7eefd404ac822ee99a45fb7c58 305 PANTHER PTHR11649:SF3 2 304 3.8E-87 T 22-04-2016 L21SP4_RS06780 5d978c7eefd404ac822ee99a45fb7c58 305 SUPERFAMILY SSF54814 189 304 6.87E-34 T 22-04-2016 IPR009019 K homology domain, prokaryotic type GO:0003723 L21SP4_RS06780 5d978c7eefd404ac822ee99a45fb7c58 305 Gene3D G3DSA:3.30.300.20 200 299 1.5E-30 T 22-04-2016 IPR015946 K homology domain-like, alpha/beta L21SP4_RS06780 5d978c7eefd404ac822ee99a45fb7c58 305 Hamap MF_00367 GTPase Era [era]. 8 304 30.086 T 22-04-2016 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 L21SP4_RS06780 5d978c7eefd404ac822ee99a45fb7c58 305 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 15 171 2.9E-18 T 22-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 L21SP4_RS06780 5d978c7eefd404ac822ee99a45fb7c58 305 Gene3D G3DSA:3.40.50.300 4 180 1.2E-37 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS06780 5d978c7eefd404ac822ee99a45fb7c58 305 PANTHER PTHR11649 2 304 3.8E-87 T 22-04-2016 L21SP4_RS06780 5d978c7eefd404ac822ee99a45fb7c58 305 SUPERFAMILY SSF52540 14 221 9.75E-39 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS06780 5d978c7eefd404ac822ee99a45fb7c58 305 Pfam PF01926 50S ribosome-binding GTPase 13 127 8.1E-19 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 L21SP4_RS06780 5d978c7eefd404ac822ee99a45fb7c58 305 Pfam PF07650 KH domain 215 293 1.6E-16 T 22-04-2016 IPR004044 K Homology domain, type 2 GO:0003723 L21SP4_RS06780 5d978c7eefd404ac822ee99a45fb7c58 305 TIGRFAM TIGR00436 era: GTP-binding protein Era 12 287 1.2E-64 T 22-04-2016 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 L21SP4_RS07300 fe333767abf71e7d850459ea33485256 183 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 19 39 - T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site L21SP4_RS02505 9c9de9a4c87f6ab3bc787d043f223fda 313 Gene3D G3DSA:3.20.20.70 117 271 3.5E-30 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP4_RS02505 9c9de9a4c87f6ab3bc787d043f223fda 313 Pfam PF13353 4Fe-4S single cluster domain 127 229 2.4E-9 T 22-04-2016 L21SP4_RS02505 9c9de9a4c87f6ab3bc787d043f223fda 313 Pfam PF04055 Radical SAM superfamily 124 263 2.4E-19 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 L21SP4_RS02505 9c9de9a4c87f6ab3bc787d043f223fda 313 SUPERFAMILY SSF102114 118 271 2.49E-32 T 22-04-2016 L21SP4_RS02505 9c9de9a4c87f6ab3bc787d043f223fda 313 PANTHER PTHR11228 66 271 3.5E-54 T 22-04-2016 L21SP4_RS02505 9c9de9a4c87f6ab3bc787d043f223fda 313 PANTHER PTHR11228:SF19 66 271 3.5E-54 T 22-04-2016 L21SP4_RS09315 8cae6ff6c1cc50c20ad3166fe90833e4 165 SUPERFAMILY SSF52833 1 160 7.47E-35 T 22-04-2016 IPR012336 Thioredoxin-like fold L21SP4_RS09315 8cae6ff6c1cc50c20ad3166fe90833e4 165 PANTHER PTHR10681:SF81 3 164 9.7E-41 T 22-04-2016 L21SP4_RS09315 8cae6ff6c1cc50c20ad3166fe90833e4 165 PANTHER PTHR10681 3 164 9.7E-41 T 22-04-2016 L21SP4_RS09315 8cae6ff6c1cc50c20ad3166fe90833e4 165 Pfam PF08534 Redoxin 20 159 9.1E-18 T 22-04-2016 IPR013740 Redoxin GO:0016491 L21SP4_RS09315 8cae6ff6c1cc50c20ad3166fe90833e4 165 Gene3D G3DSA:3.40.30.10 2 164 1.1E-39 T 22-04-2016 IPR012336 Thioredoxin-like fold L21SP4_RS01530 08a1ffdbefa0cb8946290258ef6376b2 529 Pfam PF00795 Carbon-nitrogen hydrolase 235 468 2.2E-25 T 22-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 L21SP4_RS01530 08a1ffdbefa0cb8946290258ef6376b2 529 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 16 510 19.066 T 22-04-2016 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 UniPathway: UPA00666 L21SP4_RS01530 08a1ffdbefa0cb8946290258ef6376b2 529 PANTHER PTHR23088 218 466 1.3E-59 T 22-04-2016 L21SP4_RS01530 08a1ffdbefa0cb8946290258ef6376b2 529 SUPERFAMILY SSF56317 232 474 6.15E-42 T 22-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 L21SP4_RS01530 08a1ffdbefa0cb8946290258ef6376b2 529 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 64 466 5.2E-92 T 22-04-2016 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 UniPathway: UPA00666 L21SP4_RS01530 08a1ffdbefa0cb8946290258ef6376b2 529 PANTHER PTHR23088:SF29 218 466 1.3E-59 T 22-04-2016 L21SP4_RS01530 08a1ffdbefa0cb8946290258ef6376b2 529 Gene3D G3DSA:3.60.110.10 228 474 1.3E-33 T 22-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 L21SP4_RS02295 7849ad9edb663165ebcb0b1f484d46f9 380 PRINTS PR00423 Cell division protein FtsZ signature 186 208 9.9E-15 T 22-04-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 L21SP4_RS02295 7849ad9edb663165ebcb0b1f484d46f9 380 PRINTS PR00423 Cell division protein FtsZ signature 124 145 9.9E-15 T 22-04-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 L21SP4_RS02295 7849ad9edb663165ebcb0b1f484d46f9 380 PRINTS PR00423 Cell division protein FtsZ signature 96 116 9.9E-15 T 22-04-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 L21SP4_RS02295 7849ad9edb663165ebcb0b1f484d46f9 380 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 12 169 1.1E-22 T 22-04-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 L21SP4_RS02295 7849ad9edb663165ebcb0b1f484d46f9 380 Pfam PF12327 FtsZ family, C-terminal domain 230 305 5.4E-6 T 22-04-2016 IPR024757 Cell division protein FtsZ, C-terminal L21SP4_RS02295 7849ad9edb663165ebcb0b1f484d46f9 380 Gene3D G3DSA:3.30.1330.20 211 304 6.7E-9 T 22-04-2016 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain L21SP4_RS02295 7849ad9edb663165ebcb0b1f484d46f9 380 SMART SM00864 11 202 2.4E-27 T 22-04-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 L21SP4_RS02295 7849ad9edb663165ebcb0b1f484d46f9 380 PANTHER PTHR30314 6 273 2.5E-38 T 22-04-2016 L21SP4_RS02295 7849ad9edb663165ebcb0b1f484d46f9 380 Gene3D G3DSA:3.40.50.1440 11 210 6.5E-46 T 22-04-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 L21SP4_RS02295 7849ad9edb663165ebcb0b1f484d46f9 380 SUPERFAMILY SSF52490 8 202 3.14E-38 T 22-04-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 L21SP4_RS02295 7849ad9edb663165ebcb0b1f484d46f9 380 SUPERFAMILY SSF55307 202 311 4.12E-9 T 22-04-2016 IPR008280 Tubulin/FtsZ, C-terminal L21SP4_RS11940 d2b681bcb411b8f1e1d2ef7c31c30cd9 177 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 1 164 2.6E-59 T 22-04-2016 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 L21SP4_RS11940 d2b681bcb411b8f1e1d2ef7c31c30cd9 177 PANTHER PTHR10938 1 165 6.0E-62 T 22-04-2016 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 L21SP4_RS11940 d2b681bcb411b8f1e1d2ef7c31c30cd9 177 SUPERFAMILY SSF54364 1 72 6.54E-29 T 22-04-2016 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 L21SP4_RS11940 d2b681bcb411b8f1e1d2ef7c31c30cd9 177 SUPERFAMILY SSF55200 77 165 1.44E-29 T 22-04-2016 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 L21SP4_RS11940 d2b681bcb411b8f1e1d2ef7c31c30cd9 177 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 78 161 3.6E-32 T 22-04-2016 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 L21SP4_RS11940 d2b681bcb411b8f1e1d2ef7c31c30cd9 177 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 1 70 2.3E-32 T 22-04-2016 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 L21SP4_RS11940 d2b681bcb411b8f1e1d2ef7c31c30cd9 177 Gene3D G3DSA:3.10.20.80 1 72 8.2E-36 T 22-04-2016 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 L21SP4_RS11940 d2b681bcb411b8f1e1d2ef7c31c30cd9 177 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 1 164 27.197 T 22-04-2016 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 L21SP4_RS11940 d2b681bcb411b8f1e1d2ef7c31c30cd9 177 ProSitePatterns PS00938 Initiation factor 3 signature. 52 65 - T 22-04-2016 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 L21SP4_RS11940 d2b681bcb411b8f1e1d2ef7c31c30cd9 177 Gene3D G3DSA:3.30.110.10 74 165 1.2E-33 T 22-04-2016 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 L21SP4_RS11620 7590d15f34d412977a0ce6bb45a489c9 732 Gene3D G3DSA:2.60.40.670 37 97 1.3E-4 T 22-04-2016 IPR000601 PKD domain L21SP4_RS11620 7590d15f34d412977a0ce6bb45a489c9 732 SUPERFAMILY SSF49299 37 97 3.79E-5 T 22-04-2016 IPR000601 PKD domain L21SP4_RS11620 7590d15f34d412977a0ce6bb45a489c9 732 Gene3D G3DSA:2.60.420.10 655 718 3.5E-6 T 22-04-2016 L21SP4_RS11620 7590d15f34d412977a0ce6bb45a489c9 732 SUPERFAMILY SSF48208 323 717 7.14E-25 T 22-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP4_RS11620 7590d15f34d412977a0ce6bb45a489c9 732 Gene3D G3DSA:1.50.10.10 426 484 1.0E-4 T 22-04-2016 IPR012341 Six-hairpin glycosidase GO:0003824 L21SP4_RS01070 d4a9f1f419b7c3ac8b41aefa94264fe3 1038 Pfam PF13646 HEAT repeats 766 837 8.4E-7 T 22-04-2016 L21SP4_RS01070 d4a9f1f419b7c3ac8b41aefa94264fe3 1038 Pfam PF13646 HEAT repeats 671 754 4.5E-10 T 22-04-2016 L21SP4_RS01070 d4a9f1f419b7c3ac8b41aefa94264fe3 1038 Pfam PF13646 HEAT repeats 586 656 9.0E-7 T 22-04-2016 L21SP4_RS01070 d4a9f1f419b7c3ac8b41aefa94264fe3 1038 Pfam PF13646 HEAT repeats 421 505 4.4E-8 T 22-04-2016 L21SP4_RS01070 d4a9f1f419b7c3ac8b41aefa94264fe3 1038 SMART SM00567 E-Z type HEAT repeats 473 508 300.0 T 22-04-2016 IPR004155 PBS lyase HEAT-like repeat L21SP4_RS01070 d4a9f1f419b7c3ac8b41aefa94264fe3 1038 SMART SM00567 E-Z type HEAT repeats 430 459 93.0 T 22-04-2016 IPR004155 PBS lyase HEAT-like repeat L21SP4_RS01070 d4a9f1f419b7c3ac8b41aefa94264fe3 1038 SMART SM00567 E-Z type HEAT repeats 625 654 28.0 T 22-04-2016 IPR004155 PBS lyase HEAT-like repeat L21SP4_RS01070 d4a9f1f419b7c3ac8b41aefa94264fe3 1038 SMART SM00567 E-Z type HEAT repeats 808 837 58.0 T 22-04-2016 IPR004155 PBS lyase HEAT-like repeat L21SP4_RS01070 d4a9f1f419b7c3ac8b41aefa94264fe3 1038 SMART SM00567 E-Z type HEAT repeats 594 623 540.0 T 22-04-2016 IPR004155 PBS lyase HEAT-like repeat L21SP4_RS01070 d4a9f1f419b7c3ac8b41aefa94264fe3 1038 SMART SM00567 E-Z type HEAT repeats 368 397 120.0 T 22-04-2016 IPR004155 PBS lyase HEAT-like repeat L21SP4_RS01070 d4a9f1f419b7c3ac8b41aefa94264fe3 1038 SMART SM00567 E-Z type HEAT repeats 712 741 500.0 T 22-04-2016 IPR004155 PBS lyase HEAT-like repeat L21SP4_RS01070 d4a9f1f419b7c3ac8b41aefa94264fe3 1038 SMART SM00567 E-Z type HEAT repeats 777 806 31.0 T 22-04-2016 IPR004155 PBS lyase HEAT-like repeat L21SP4_RS01070 d4a9f1f419b7c3ac8b41aefa94264fe3 1038 SUPERFAMILY SSF48371 390 742 2.26E-21 T 22-04-2016 IPR016024 Armadillo-type fold GO:0005488 L21SP4_RS01070 d4a9f1f419b7c3ac8b41aefa94264fe3 1038 SUPERFAMILY SSF48371 775 825 2.26E-21 T 22-04-2016 IPR016024 Armadillo-type fold GO:0005488 L21SP4_RS01070 d4a9f1f419b7c3ac8b41aefa94264fe3 1038 Gene3D G3DSA:1.25.10.10 376 537 3.7E-12 T 22-04-2016 IPR011989 Armadillo-like helical L21SP4_RS01070 d4a9f1f419b7c3ac8b41aefa94264fe3 1038 Gene3D G3DSA:1.25.10.10 538 756 2.0E-19 T 22-04-2016 IPR011989 Armadillo-like helical L21SP4_RS01070 d4a9f1f419b7c3ac8b41aefa94264fe3 1038 Pfam PF14100 Methane oxygenase PmoA 35 295 3.2E-58 T 22-04-2016 IPR029475 Methane oxygenase PmoA L21SP4_RS08750 d326413a04c78aab354e00a457f2a6df 222 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 1 219 1.1E-65 T 22-04-2016 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|UniPathway: UPA00079 L21SP4_RS08750 d326413a04c78aab354e00a457f2a6df 222 PANTHER PTHR10108 1 222 2.3E-60 T 22-04-2016 L21SP4_RS08750 d326413a04c78aab354e00a457f2a6df 222 Gene3D G3DSA:3.40.50.150 1 212 3.1E-42 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS08750 d326413a04c78aab354e00a457f2a6df 222 Pfam PF01209 ubiE/COQ5 methyltransferase family 1 217 1.2E-52 T 22-04-2016 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|UniPathway: UPA00079 L21SP4_RS08750 d326413a04c78aab354e00a457f2a6df 222 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 1 219 28.544 T 22-04-2016 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|UniPathway: UPA00079 L21SP4_RS08750 d326413a04c78aab354e00a457f2a6df 222 SUPERFAMILY SSF53335 1 212 5.94E-43 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS08750 d326413a04c78aab354e00a457f2a6df 222 PANTHER PTHR10108:SF24 1 222 2.3E-60 T 22-04-2016 L21SP4_RS08750 d326413a04c78aab354e00a457f2a6df 222 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 9 24 - T 22-04-2016 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|UniPathway: UPA00079 L21SP4_RS03585 cfd567c7eac430cedd8564da7676a356 403 Gene3D G3DSA:2.160.10.10 29 132 1.6E-7 T 22-04-2016 L21SP4_RS03585 cfd567c7eac430cedd8564da7676a356 403 Gene3D G3DSA:2.160.10.10 194 233 1.6E-7 T 22-04-2016 L21SP4_RS03585 cfd567c7eac430cedd8564da7676a356 403 SUPERFAMILY SSF51161 37 228 3.76E-9 T 22-04-2016 IPR011004 Trimeric LpxA-like L21SP4_RS05565 8d999b98ad5d2f7f2a14767aa6c21ddc 388 PANTHER PTHR22604:SF123 1 386 4.0E-71 T 22-04-2016 L21SP4_RS05565 8d999b98ad5d2f7f2a14767aa6c21ddc 388 PANTHER PTHR22604 1 386 4.0E-71 T 22-04-2016 L21SP4_RS05565 8d999b98ad5d2f7f2a14767aa6c21ddc 388 Gene3D G3DSA:3.30.360.10 327 385 6.2E-38 T 22-04-2016 L21SP4_RS05565 8d999b98ad5d2f7f2a14767aa6c21ddc 388 Gene3D G3DSA:3.30.360.10 156 278 6.2E-38 T 22-04-2016 L21SP4_RS05565 8d999b98ad5d2f7f2a14767aa6c21ddc 388 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 5 133 1.4E-22 T 22-04-2016 IPR000683 Oxidoreductase, N-terminal GO:0016491 L21SP4_RS05565 8d999b98ad5d2f7f2a14767aa6c21ddc 388 SUPERFAMILY SSF55347 142 324 1.41E-35 T 22-04-2016 L21SP4_RS05565 8d999b98ad5d2f7f2a14767aa6c21ddc 388 SUPERFAMILY SSF51735 3 166 3.57E-40 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS05565 8d999b98ad5d2f7f2a14767aa6c21ddc 388 Gene3D G3DSA:3.40.50.720 1 155 4.1E-42 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS06000 cdecc93069a6a1fb8e93f8b8ccbacdf0 457 Pfam PF12951 Passenger-associated-transport-repeat 304 331 1.7E-7 T 22-04-2016 IPR013425 Autotransporter-associated beta strand repeat L21SP4_RS06000 cdecc93069a6a1fb8e93f8b8ccbacdf0 457 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 432 454 7.4E-4 T 22-04-2016 IPR013424 PEP-CTERM protein-sorting domain L21SP4_RS06000 cdecc93069a6a1fb8e93f8b8ccbacdf0 457 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 304 331 1.2E-10 T 22-04-2016 IPR013425 Autotransporter-associated beta strand repeat L21SP4_RS01895 528962fdfc246a046dd78d51c938a4e3 310 SMART SM00116 98 146 1.4E-4 T 22-04-2016 IPR000644 CBS domain L21SP4_RS01895 528962fdfc246a046dd78d51c938a4e3 310 SMART SM00116 36 83 1.3E-5 T 22-04-2016 IPR000644 CBS domain L21SP4_RS01895 528962fdfc246a046dd78d51c938a4e3 310 Pfam PF00571 CBS domain 95 146 6.5E-7 T 22-04-2016 IPR000644 CBS domain L21SP4_RS01895 528962fdfc246a046dd78d51c938a4e3 310 Pfam PF00571 CBS domain 29 82 1.5E-9 T 22-04-2016 IPR000644 CBS domain L21SP4_RS01895 528962fdfc246a046dd78d51c938a4e3 310 Gene3D G3DSA:3.20.20.70 27 169 3.5E-25 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP4_RS01895 528962fdfc246a046dd78d51c938a4e3 310 SUPERFAMILY SSF55874 205 304 1.03E-8 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS01895 528962fdfc246a046dd78d51c938a4e3 310 PANTHER PTHR11911 18 172 4.4E-19 T 22-04-2016 L21SP4_RS01895 528962fdfc246a046dd78d51c938a4e3 310 SUPERFAMILY SSF54631 26 150 8.72E-26 T 22-04-2016 L21SP4_RS01895 528962fdfc246a046dd78d51c938a4e3 310 Pfam PF13581 Histidine kinase-like ATPase domain 187 302 4.8E-8 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS01895 528962fdfc246a046dd78d51c938a4e3 310 Gene3D G3DSA:3.30.565.10 199 309 4.7E-10 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS05525 b0e9dca53922ff36f509ffae8fd2410e 247 PANTHER PTHR11019 111 247 3.7E-30 T 22-04-2016 L21SP4_RS05525 b0e9dca53922ff36f509ffae8fd2410e 247 SUPERFAMILY SSF46689 142 192 2.55E-10 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS05525 b0e9dca53922ff36f509ffae8fd2410e 247 SUPERFAMILY SSF55785 18 130 2.97E-13 T 22-04-2016 IPR000014 PAS domain L21SP4_RS05525 b0e9dca53922ff36f509ffae8fd2410e 247 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 195 237 - T 22-04-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 L21SP4_RS05525 b0e9dca53922ff36f509ffae8fd2410e 247 Gene3D G3DSA:1.10.10.60 140 194 3.8E-16 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS05525 b0e9dca53922ff36f509ffae8fd2410e 247 Gene3D G3DSA:1.10.10.60 195 242 2.3E-17 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS05525 b0e9dca53922ff36f509ffae8fd2410e 247 Pfam PF12833 Helix-turn-helix domain 164 241 5.7E-26 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP4_RS05525 b0e9dca53922ff36f509ffae8fd2410e 247 SMART SM00342 158 241 8.0E-32 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP4_RS05525 b0e9dca53922ff36f509ffae8fd2410e 247 Gene3D G3DSA:3.30.450.20 19 132 1.9E-13 T 22-04-2016 L21SP4_RS05525 b0e9dca53922ff36f509ffae8fd2410e 247 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 210 225 7.7E-5 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 L21SP4_RS05525 b0e9dca53922ff36f509ffae8fd2410e 247 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 225 241 7.7E-5 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 L21SP4_RS05525 b0e9dca53922ff36f509ffae8fd2410e 247 SUPERFAMILY SSF46689 194 242 3.45E-13 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS05525 b0e9dca53922ff36f509ffae8fd2410e 247 Pfam PF08448 PAS fold 25 136 2.6E-18 T 22-04-2016 IPR013656 PAS fold-4 L21SP4_RS05525 b0e9dca53922ff36f509ffae8fd2410e 247 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 29 136 1.9E-6 T 22-04-2016 IPR000014 PAS domain L21SP4_RS02640 3a109a8f2d65c28fdae2bd384fd3c6bd 160 Gene3D G3DSA:3.40.920.10 6 97 4.5E-19 T 22-04-2016 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 L21SP4_RS02640 3a109a8f2d65c28fdae2bd384fd3c6bd 160 SUPERFAMILY SSF53323 7 158 2.48E-28 T 22-04-2016 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 L21SP4_RS02640 3a109a8f2d65c28fdae2bd384fd3c6bd 160 PANTHER PTHR32154:SF22 7 156 3.7E-32 T 22-04-2016 L21SP4_RS02640 3a109a8f2d65c28fdae2bd384fd3c6bd 160 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 15 97 8.9E-18 T 22-04-2016 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 L21SP4_RS02640 3a109a8f2d65c28fdae2bd384fd3c6bd 160 PANTHER PTHR32154 7 156 3.7E-32 T 22-04-2016 L21SP4_RS03785 68e050efd08e9e8b086129337a0d74c6 296 Pfam PF13525 Outer membrane lipoprotein 121 283 3.8E-9 T 22-04-2016 L21SP4_RS03785 68e050efd08e9e8b086129337a0d74c6 296 Pfam PF13432 Tetratricopeptide repeat 24 85 0.016 T 22-04-2016 L21SP4_RS03785 68e050efd08e9e8b086129337a0d74c6 296 SMART SM00028 55 88 160.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS03785 68e050efd08e9e8b086129337a0d74c6 296 SMART SM00028 238 272 26.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS03785 68e050efd08e9e8b086129337a0d74c6 296 SMART SM00028 142 175 7.3 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS03785 68e050efd08e9e8b086129337a0d74c6 296 SUPERFAMILY SSF48452 23 272 2.25E-9 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS03785 68e050efd08e9e8b086129337a0d74c6 296 Gene3D G3DSA:1.25.40.10 23 274 4.2E-13 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS05215 282c2cf271df91457beb9b62d0386a31 363 PANTHER PTHR30307:SF0 12 363 3.6E-153 T 22-04-2016 L21SP4_RS05215 282c2cf271df91457beb9b62d0386a31 363 Gene3D G3DSA:2.40.10.240 74 153 1.3E-19 T 22-04-2016 L21SP4_RS05215 282c2cf271df91457beb9b62d0386a31 363 Gene3D G3DSA:3.40.1780.10 194 363 1.0E-88 T 22-04-2016 L21SP4_RS05215 282c2cf271df91457beb9b62d0386a31 363 Gene3D G3DSA:3.40.1780.10 12 72 1.0E-88 T 22-04-2016 L21SP4_RS05215 282c2cf271df91457beb9b62d0386a31 363 SUPERFAMILY SSF111337 13 363 1.15E-123 T 22-04-2016 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700|UniPathway: UPA00392 L21SP4_RS05215 282c2cf271df91457beb9b62d0386a31 363 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 12 363 7.6E-112 T 22-04-2016 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700|UniPathway: UPA00392 L21SP4_RS05215 282c2cf271df91457beb9b62d0386a31 363 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 11 363 43.512 T 22-04-2016 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700|UniPathway: UPA00392 L21SP4_RS05215 282c2cf271df91457beb9b62d0386a31 363 Pfam PF02547 Queuosine biosynthesis protein 14 362 1.6E-126 T 22-04-2016 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700|UniPathway: UPA00392 L21SP4_RS05215 282c2cf271df91457beb9b62d0386a31 363 PANTHER PTHR30307 12 363 3.6E-153 T 22-04-2016 L21SP4_RS06170 a24acb19f826b05890ff3ec35d6119ce 149 Gene3D G3DSA:3.50.80.10 1 145 9.1E-53 T 22-04-2016 IPR023509 D-Tyr tRNAtyr deacylase-like domain L21SP4_RS06170 a24acb19f826b05890ff3ec35d6119ce 149 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 2 144 3.7E-49 T 22-04-2016 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 L21SP4_RS06170 a24acb19f826b05890ff3ec35d6119ce 149 PANTHER PTHR10472 2 145 1.2E-61 T 22-04-2016 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 L21SP4_RS06170 a24acb19f826b05890ff3ec35d6119ce 149 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 1 145 2.1E-48 T 22-04-2016 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 L21SP4_RS06170 a24acb19f826b05890ff3ec35d6119ce 149 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 145 33.127 T 22-04-2016 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 L21SP4_RS06170 a24acb19f826b05890ff3ec35d6119ce 149 SUPERFAMILY SSF69500 1 144 3.92E-51 T 22-04-2016 IPR023509 D-Tyr tRNAtyr deacylase-like domain L21SP4_RS03010 5df33c3211424be6937a11629f7dd58b 267 SUPERFAMILY SSF52540 14 263 1.99E-28 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS03010 5df33c3211424be6937a11629f7dd58b 267 Gene3D G3DSA:3.40.50.300 39 168 2.8E-10 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS03010 5df33c3211424be6937a11629f7dd58b 267 PANTHER PTHR35894:SF1 4 267 3.0E-55 T 22-04-2016 L21SP4_RS03010 5df33c3211424be6937a11629f7dd58b 267 PANTHER PTHR35894 4 267 3.0E-55 T 22-04-2016 L21SP4_RS03010 5df33c3211424be6937a11629f7dd58b 267 Pfam PF13401 AAA domain 43 173 5.4E-13 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS02555 88af5d50386dbab03e376ed203aba378 336 Pfam PF08239 Bacterial SH3 domain 99 149 4.1E-7 T 22-04-2016 IPR003646 SH3-like domain, bacterial-type L21SP4_RS07185 0622881786c94b375c89643c6ecbd8e6 242 PANTHER PTHR24322 144 174 1.1E-27 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS07185 0622881786c94b375c89643c6ecbd8e6 242 PANTHER PTHR24322 9 128 1.1E-27 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS07185 0622881786c94b375c89643c6ecbd8e6 242 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 234 4.8E-49 T 22-04-2016 L21SP4_RS07185 0622881786c94b375c89643c6ecbd8e6 242 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 174 8.6E-4 T 22-04-2016 L21SP4_RS07185 0622881786c94b375c89643c6ecbd8e6 242 SUPERFAMILY SSF51735 5 236 3.66E-58 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS07185 0622881786c94b375c89643c6ecbd8e6 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 181 1.4E-22 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS07185 0622881786c94b375c89643c6ecbd8e6 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.4E-22 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS07185 0622881786c94b375c89643c6ecbd8e6 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 199 219 1.4E-22 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS07185 0622881786c94b375c89643c6ecbd8e6 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 163 1.4E-22 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS07185 0622881786c94b375c89643c6ecbd8e6 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 118 134 1.4E-22 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS07185 0622881786c94b375c89643c6ecbd8e6 242 Gene3D G3DSA:3.40.50.720 6 236 2.3E-58 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS11110 ea4922d9154a525d2c12e1950fdb2636 297 Gene3D G3DSA:3.40.190.10 21 131 1.1E-35 T 22-04-2016 L21SP4_RS11110 ea4922d9154a525d2c12e1950fdb2636 297 Gene3D G3DSA:3.40.190.10 238 296 1.2E-12 T 22-04-2016 L21SP4_RS11110 ea4922d9154a525d2c12e1950fdb2636 297 SUPERFAMILY SSF53850 22 294 9.23E-64 T 22-04-2016 L21SP4_RS11110 ea4922d9154a525d2c12e1950fdb2636 297 PANTHER PTHR30177 22 296 1.8E-80 T 22-04-2016 L21SP4_RS11110 ea4922d9154a525d2c12e1950fdb2636 297 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 23 292 1.2E-63 T 22-04-2016 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 L21SP4_RS11110 ea4922d9154a525d2c12e1950fdb2636 297 Gene3D G3DSA:3.40.190.120 132 233 2.3E-30 T 22-04-2016 L21SP4_RS11110 ea4922d9154a525d2c12e1950fdb2636 297 PANTHER PTHR30177:SF9 22 296 1.8E-80 T 22-04-2016 L21SP4_RS01125 063e785be6df3e2b97d253c4b1685d7a 84 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 79 1.5E-31 T 22-04-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS01125 063e785be6df3e2b97d253c4b1685d7a 84 PANTHER PTHR15893 1 71 1.3E-38 T 22-04-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS01125 063e785be6df3e2b97d253c4b1685d7a 84 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 81 24.598 T 22-04-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS01125 063e785be6df3e2b97d253c4b1685d7a 84 Pfam PF01016 Ribosomal L27 protein 2 79 4.9E-33 T 22-04-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS01125 063e785be6df3e2b97d253c4b1685d7a 84 PRINTS PR00063 Ribosomal protein L27 signature 4 28 2.13E-33 T 22-04-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS01125 063e785be6df3e2b97d253c4b1685d7a 84 PRINTS PR00063 Ribosomal protein L27 signature 29 53 2.13E-33 T 22-04-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS01125 063e785be6df3e2b97d253c4b1685d7a 84 PRINTS PR00063 Ribosomal protein L27 signature 54 78 2.13E-33 T 22-04-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS01125 063e785be6df3e2b97d253c4b1685d7a 84 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 28 79 2.0E-12 T 22-04-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS01125 063e785be6df3e2b97d253c4b1685d7a 84 SUPERFAMILY SSF110324 2 80 4.53E-30 T 22-04-2016 L21SP4_RS01125 063e785be6df3e2b97d253c4b1685d7a 84 Gene3D G3DSA:2.40.50.100 20 80 1.7E-26 T 22-04-2016 L21SP4_RS06565 c8b0f13229b909c887564902da41e3fa 517 Pfam PF13005 zinc-finger binding domain of transposase IS66 130 173 2.2E-7 T 22-04-2016 IPR024474 Zinc-finger binding domain of transposase IS66 L21SP4_RS06565 c8b0f13229b909c887564902da41e3fa 517 PANTHER PTHR33678 17 517 3.4E-125 T 22-04-2016 L21SP4_RS06565 c8b0f13229b909c887564902da41e3fa 517 PANTHER PTHR33678:SF2 17 517 3.4E-125 T 22-04-2016 L21SP4_RS06565 c8b0f13229b909c887564902da41e3fa 517 Pfam PF03050 Transposase IS66 family 189 479 3.0E-60 T 22-04-2016 IPR004291 Transposase, IS66 L21SP4_RS02070 3bdb5e375597f47dc692dc4d89542c12 328 Gene3D G3DSA:1.10.260.40 1 35 8.4E-6 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 L21SP4_RS02070 3bdb5e375597f47dc692dc4d89542c12 328 PANTHER PTHR30146 1 324 9.7E-61 T 22-04-2016 L21SP4_RS02070 3bdb5e375597f47dc692dc4d89542c12 328 Gene3D G3DSA:3.40.50.2300 53 155 2.3E-15 T 22-04-2016 L21SP4_RS02070 3bdb5e375597f47dc692dc4d89542c12 328 Gene3D G3DSA:3.40.50.2300 156 320 3.2E-47 T 22-04-2016 L21SP4_RS02070 3bdb5e375597f47dc692dc4d89542c12 328 SUPERFAMILY SSF53822 54 324 1.13E-51 T 22-04-2016 IPR028082 Periplasmic binding protein-like I L21SP4_RS02070 3bdb5e375597f47dc692dc4d89542c12 328 Pfam PF13377 Periplasmic binding protein-like domain 152 318 8.5E-32 T 22-04-2016 L21SP4_RS03910 4a91389806bdffab7a2f6c56fbd085d5 494 Pfam PF13005 zinc-finger binding domain of transposase IS66 116 159 2.1E-7 T 22-04-2016 IPR024474 Zinc-finger binding domain of transposase IS66 L21SP4_RS03910 4a91389806bdffab7a2f6c56fbd085d5 494 Pfam PF03050 Transposase IS66 family 175 456 3.5E-60 T 22-04-2016 IPR004291 Transposase, IS66 L21SP4_RS03910 4a91389806bdffab7a2f6c56fbd085d5 494 PANTHER PTHR33678:SF2 17 494 1.0E-127 T 22-04-2016 L21SP4_RS03910 4a91389806bdffab7a2f6c56fbd085d5 494 PANTHER PTHR33678 17 494 1.0E-127 T 22-04-2016 L21SP4_RS08910 d54b0c3ad1a8d198f4ed577df47e87cb 352 SUPERFAMILY SSF53649 10 347 2.36E-101 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS08910 d54b0c3ad1a8d198f4ed577df47e87cb 352 PRINTS PR00113 Alkaline phosphatase signature 215 244 1.1E-29 T 22-04-2016 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 L21SP4_RS08910 d54b0c3ad1a8d198f4ed577df47e87cb 352 PRINTS PR00113 Alkaline phosphatase signature 155 165 1.1E-29 T 22-04-2016 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 L21SP4_RS08910 d54b0c3ad1a8d198f4ed577df47e87cb 352 PRINTS PR00113 Alkaline phosphatase signature 111 131 1.1E-29 T 22-04-2016 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 L21SP4_RS08910 d54b0c3ad1a8d198f4ed577df47e87cb 352 PRINTS PR00113 Alkaline phosphatase signature 28 48 1.1E-29 T 22-04-2016 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 L21SP4_RS08910 d54b0c3ad1a8d198f4ed577df47e87cb 352 Gene3D G3DSA:3.40.720.10 20 346 1.4E-97 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS08910 d54b0c3ad1a8d198f4ed577df47e87cb 352 Pfam PF00245 Alkaline phosphatase 216 289 2.3E-22 T 22-04-2016 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 L21SP4_RS08910 d54b0c3ad1a8d198f4ed577df47e87cb 352 Pfam PF00245 Alkaline phosphatase 29 169 3.1E-37 T 22-04-2016 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 L21SP4_RS08910 d54b0c3ad1a8d198f4ed577df47e87cb 352 Pfam PF00245 Alkaline phosphatase 302 345 3.7E-5 T 22-04-2016 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 L21SP4_RS08910 d54b0c3ad1a8d198f4ed577df47e87cb 352 ProSitePatterns PS00123 Alkaline phosphatase active site. 74 82 - T 22-04-2016 IPR018299 Alkaline phosphatase, active site GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 L21SP4_RS08910 d54b0c3ad1a8d198f4ed577df47e87cb 352 SMART SM00098 29 352 2.9E-50 T 22-04-2016 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 L21SP4_RS08910 d54b0c3ad1a8d198f4ed577df47e87cb 352 PANTHER PTHR11596:SF5 25 340 1.2E-87 T 22-04-2016 L21SP4_RS08910 d54b0c3ad1a8d198f4ed577df47e87cb 352 PANTHER PTHR11596 25 340 1.2E-87 T 22-04-2016 L21SP4_RS09305 35326f01a81c00229377f91f694f8328 213 SUPERFAMILY SSF52540 1 211 1.01E-52 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS09305 35326f01a81c00229377f91f694f8328 213 PANTHER PTHR24220:SF66 3 211 5.2E-67 T 22-04-2016 L21SP4_RS09305 35326f01a81c00229377f91f694f8328 213 Gene3D G3DSA:3.40.50.300 1 211 3.3E-56 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS09305 35326f01a81c00229377f91f694f8328 213 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 L21SP4_RS09305 35326f01a81c00229377f91f694f8328 213 Pfam PF00005 ABC transporter 18 164 1.6E-30 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 L21SP4_RS09305 35326f01a81c00229377f91f694f8328 213 SMART SM00382 27 210 5.1E-13 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS09305 35326f01a81c00229377f91f694f8328 213 PANTHER PTHR24220 3 211 5.2E-67 T 22-04-2016 L21SP4_RS07670 9010754c8097c77851b74f6e44aca12a 229 PANTHER PTHR24220:SF452 7 225 5.5E-113 T 22-04-2016 L21SP4_RS07670 9010754c8097c77851b74f6e44aca12a 229 PANTHER PTHR24220 7 225 5.5E-113 T 22-04-2016 L21SP4_RS07670 9010754c8097c77851b74f6e44aca12a 229 Pfam PF00005 ABC transporter 25 173 9.9E-32 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 L21SP4_RS07670 9010754c8097c77851b74f6e44aca12a 229 SMART SM00382 34 222 2.7E-16 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS07670 9010754c8097c77851b74f6e44aca12a 229 Gene3D G3DSA:3.40.50.300 4 226 4.3E-69 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS07670 9010754c8097c77851b74f6e44aca12a 229 SUPERFAMILY SSF52540 5 226 9.87E-70 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS07560 64192f9b2e3677bc25aa58d192980891 195 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 16 152 7.1E-35 T 22-04-2016 IPR006543 Histidinol-phosphate phosphatase GO:0016791 L21SP4_RS07560 64192f9b2e3677bc25aa58d192980891 195 PANTHER PTHR23133 16 186 7.0E-28 T 22-04-2016 L21SP4_RS07560 64192f9b2e3677bc25aa58d192980891 195 PIRSF PIRSF004682 8 188 5.9E-45 T 22-04-2016 IPR004446 D,D-heptose 1,7-bisphosphate phosphatase GO:0005975|GO:0016791 L21SP4_RS07560 64192f9b2e3677bc25aa58d192980891 195 Pfam PF13242 HAD-hyrolase-like 110 179 2.4E-8 T 22-04-2016 L21SP4_RS07560 64192f9b2e3677bc25aa58d192980891 195 PANTHER PTHR23133:SF3 16 186 7.0E-28 T 22-04-2016 L21SP4_RS07560 64192f9b2e3677bc25aa58d192980891 195 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 16 152 3.5E-25 T 22-04-2016 IPR006549 HAD-superfamily hydrolase,subfamily IIIA L21SP4_RS07560 64192f9b2e3677bc25aa58d192980891 195 Gene3D G3DSA:3.40.50.1000 13 184 1.2E-45 T 22-04-2016 IPR023214 HAD-like domain L21SP4_RS07560 64192f9b2e3677bc25aa58d192980891 195 SUPERFAMILY SSF56784 14 186 5.51E-38 T 22-04-2016 IPR023214 HAD-like domain L21SP4_RS05955 e506c58c08158def7c2a8b1a163115e3 802 SUPERFAMILY SSF49785 658 799 8.08E-30 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS05955 e506c58c08158def7c2a8b1a163115e3 802 PANTHER PTHR31151 90 538 3.3E-51 T 22-04-2016 L21SP4_RS05955 e506c58c08158def7c2a8b1a163115e3 802 SMART SM00776 654 801 3.4E-25 T 22-04-2016 IPR013222 Glycosyl hydrolase family 98, putative carbohydrate-binding module L21SP4_RS05955 e506c58c08158def7c2a8b1a163115e3 802 Pfam PF08305 NPCBM/NEW2 domain 658 799 1.6E-30 T 22-04-2016 IPR013222 Glycosyl hydrolase family 98, putative carbohydrate-binding module L21SP4_RS05955 e506c58c08158def7c2a8b1a163115e3 802 Pfam PF07944 Beta-L-arabinofuranosidase, GH127 90 538 7.0E-68 T 22-04-2016 IPR012878 Beta-L-arabinofuranosidase, GH127 KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18 L21SP4_RS05915 d4fda795e152888362de3f805f1868fd 195 SUPERFAMILY SSF140478 25 183 3.4E-57 T 22-04-2016 IPR023353 LemA-like domain L21SP4_RS05915 d4fda795e152888362de3f805f1868fd 195 Pfam PF04011 LemA family 6 195 7.4E-71 T 22-04-2016 IPR007156 LemA L21SP4_RS05915 d4fda795e152888362de3f805f1868fd 195 PANTHER PTHR34478 1 195 8.1E-80 T 22-04-2016 L21SP4_RS05915 d4fda795e152888362de3f805f1868fd 195 Gene3D G3DSA:1.20.1440.20 13 195 6.5E-67 T 22-04-2016 IPR023353 LemA-like domain L21SP4_RS05915 d4fda795e152888362de3f805f1868fd 195 PANTHER PTHR34478:SF2 1 195 8.1E-80 T 22-04-2016 L21SP4_RS10675 444e18e39152f7ba55d1576680484dce 483 Pfam PF13185 GAF domain 68 224 4.0E-18 T 22-04-2016 IPR003018 GAF domain GO:0005515 L21SP4_RS10675 444e18e39152f7ba55d1576680484dce 483 Gene3D G3DSA:3.30.450.40 49 239 9.6E-27 T 22-04-2016 IPR029016 GAF domain-like L21SP4_RS10675 444e18e39152f7ba55d1576680484dce 483 SUPERFAMILY SSF81606 277 482 7.06E-9 T 22-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 L21SP4_RS10675 444e18e39152f7ba55d1576680484dce 483 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 290 483 1.6E-47 T 22-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 L21SP4_RS10675 444e18e39152f7ba55d1576680484dce 483 SMART SM00065 68 236 2.2E-19 T 22-04-2016 IPR003018 GAF domain GO:0005515 L21SP4_RS10675 444e18e39152f7ba55d1576680484dce 483 PANTHER PTHR21021:SF19 143 483 2.3E-80 T 22-04-2016 L21SP4_RS10675 444e18e39152f7ba55d1576680484dce 483 SMART SM00331 263 482 8.3E-49 T 22-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 L21SP4_RS10675 444e18e39152f7ba55d1576680484dce 483 SUPERFAMILY SSF55781 51 257 4.36E-29 T 22-04-2016 IPR029016 GAF domain-like L21SP4_RS10675 444e18e39152f7ba55d1576680484dce 483 PANTHER PTHR21021 143 483 2.3E-80 T 22-04-2016 L21SP4_RS03705 d6fb20c46ae7d360f5d130b8e61bc053 465 PANTHER PTHR11907:SF0 59 401 1.1E-81 T 22-04-2016 L21SP4_RS03705 d6fb20c46ae7d360f5d130b8e61bc053 465 PANTHER PTHR11907:SF0 421 465 1.1E-81 T 22-04-2016 L21SP4_RS03705 d6fb20c46ae7d360f5d130b8e61bc053 465 PANTHER PTHR11907 59 401 1.1E-81 T 22-04-2016 L21SP4_RS03705 d6fb20c46ae7d360f5d130b8e61bc053 465 PANTHER PTHR11907 421 465 1.1E-81 T 22-04-2016 L21SP4_RS03705 d6fb20c46ae7d360f5d130b8e61bc053 465 PIRSF PIRSF000485 1 465 1.5E-99 T 22-04-2016 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|UniPathway: UPA00074 L21SP4_RS03705 d6fb20c46ae7d360f5d130b8e61bc053 465 SUPERFAMILY SSF56235 3 238 2.74E-29 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal L21SP4_RS03705 d6fb20c46ae7d360f5d130b8e61bc053 465 SUPERFAMILY SSF53271 232 398 1.81E-29 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like L21SP4_RS03705 d6fb20c46ae7d360f5d130b8e61bc053 465 SUPERFAMILY SSF53271 426 464 1.81E-29 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like L21SP4_RS03705 d6fb20c46ae7d360f5d130b8e61bc053 465 Gene3D G3DSA:3.60.20.10 3 238 1.3E-17 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal L21SP4_RS03705 d6fb20c46ae7d360f5d130b8e61bc053 465 Gene3D G3DSA:3.40.50.2020 253 382 4.0E-31 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like L21SP4_RS03705 d6fb20c46ae7d360f5d130b8e61bc053 465 Gene3D G3DSA:3.40.50.2020 421 449 4.0E-31 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like L21SP4_RS03705 d6fb20c46ae7d360f5d130b8e61bc053 465 Pfam PF13537 Glutamine amidotransferase domain 73 195 3.9E-14 T 22-04-2016 IPR017932 Glutamine amidotransferase type 2 domain L21SP4_RS04255 79e0be5bd5e533e4e078c431c50ed268 287 Pfam PF02811 PHP domain 3 69 1.7E-10 T 22-04-2016 IPR004013 PHP domain GO:0003824 L21SP4_RS04255 79e0be5bd5e533e4e078c431c50ed268 287 SMART SM00481 2 67 6.6E-17 T 22-04-2016 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 L21SP4_RS04255 79e0be5bd5e533e4e078c431c50ed268 287 PANTHER PTHR30007 1 249 1.5E-56 T 22-04-2016 L21SP4_RS04255 79e0be5bd5e533e4e078c431c50ed268 287 SUPERFAMILY SSF89550 1 80 2.35E-42 T 22-04-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 L21SP4_RS04255 79e0be5bd5e533e4e078c431c50ed268 287 SUPERFAMILY SSF89550 162 252 2.35E-42 T 22-04-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 L21SP4_RS04255 79e0be5bd5e533e4e078c431c50ed268 287 PANTHER PTHR30007:SF4 1 249 1.5E-56 T 22-04-2016 L21SP4_RS04255 79e0be5bd5e533e4e078c431c50ed268 287 Gene3D G3DSA:3.20.20.140 154 255 8.7E-37 T 22-04-2016 L21SP4_RS04255 79e0be5bd5e533e4e078c431c50ed268 287 Gene3D G3DSA:3.20.20.140 1 86 8.7E-37 T 22-04-2016 L21SP4_RS04530 4272dc7df813f7c0131c98bd14c49339 401 PANTHER PTHR33307 1 187 4.9E-63 T 22-04-2016 L21SP4_RS04530 4272dc7df813f7c0131c98bd14c49339 401 PANTHER PTHR33307 215 401 4.9E-63 T 22-04-2016 L21SP4_RS04530 4272dc7df813f7c0131c98bd14c49339 401 SUPERFAMILY SSF48208 11 356 6.21E-29 T 22-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP4_RS04530 4272dc7df813f7c0131c98bd14c49339 401 PANTHER PTHR33307:SF5 1 187 4.9E-63 T 22-04-2016 L21SP4_RS04530 4272dc7df813f7c0131c98bd14c49339 401 PANTHER PTHR33307:SF5 215 401 4.9E-63 T 22-04-2016 L21SP4_RS04530 4272dc7df813f7c0131c98bd14c49339 401 Pfam PF05592 Bacterial alpha-L-rhamnosidase 3 179 4.7E-20 T 22-04-2016 IPR008902 Bacterial alpha-L-rhamnosidase L21SP4_RS04530 4272dc7df813f7c0131c98bd14c49339 401 Pfam PF05592 Bacterial alpha-L-rhamnosidase 215 355 3.4E-33 T 22-04-2016 IPR008902 Bacterial alpha-L-rhamnosidase L21SP4_RS05580 0d15b543c94590727ef407b3db739e8e 432 PANTHER PTHR22604 1 415 1.6E-88 T 22-04-2016 L21SP4_RS05580 0d15b543c94590727ef407b3db739e8e 432 Gene3D G3DSA:3.30.360.10 186 406 5.6E-16 T 22-04-2016 L21SP4_RS05580 0d15b543c94590727ef407b3db739e8e 432 Gene3D G3DSA:3.40.50.720 34 185 1.0E-37 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS05580 0d15b543c94590727ef407b3db739e8e 432 PANTHER PTHR22604:SF122 1 415 1.6E-88 T 22-04-2016 L21SP4_RS05580 0d15b543c94590727ef407b3db739e8e 432 SUPERFAMILY SSF51735 29 192 4.34E-36 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS05580 0d15b543c94590727ef407b3db739e8e 432 SUPERFAMILY SSF55347 176 335 8.5E-12 T 22-04-2016 L21SP4_RS05580 0d15b543c94590727ef407b3db739e8e 432 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 41 162 9.0E-16 T 22-04-2016 IPR000683 Oxidoreductase, N-terminal GO:0016491 L21SP4_RS06045 338dac5af67836526bb255e79af7aeda 580 SUPERFAMILY SSF51445 106 391 2.99E-13 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily L21SP4_RS06045 338dac5af67836526bb255e79af7aeda 580 Pfam PF01229 Glycosyl hydrolases family 39 150 278 2.3E-8 T 22-04-2016 IPR000514 Glycoside hydrolase, family 39 GO:0004553|GO:0005975 L21SP4_RS06045 338dac5af67836526bb255e79af7aeda 580 Gene3D G3DSA:3.20.20.80 74 371 9.1E-16 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP4_RS05880 dbdc1da1997be3d6f096f63ddc68b34d 319 Pfam PF13469 Sulfotransferase family 112 208 1.6E-8 T 22-04-2016 L21SP4_RS05880 dbdc1da1997be3d6f096f63ddc68b34d 319 SUPERFAMILY SSF52540 99 218 2.7E-21 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS05880 dbdc1da1997be3d6f096f63ddc68b34d 319 SUPERFAMILY SSF52540 7 66 2.7E-21 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS05880 dbdc1da1997be3d6f096f63ddc68b34d 319 Gene3D G3DSA:3.40.50.300 9 310 5.1E-17 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS02370 00ca3f5c6cc53864bb997a3c7fea7a61 397 Pfam PF02646 RmuC family 82 379 7.0E-106 T 22-04-2016 IPR003798 DNA recombination RmuC L21SP4_RS02370 00ca3f5c6cc53864bb997a3c7fea7a61 397 PANTHER PTHR30563 18 389 2.4E-102 T 22-04-2016 L21SP4_RS04850 48c1399715b3317ef5be20e740a09288 281 SUPERFAMILY SSF55120 80 279 1.19E-53 T 22-04-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 L21SP4_RS04850 48c1399715b3317ef5be20e740a09288 281 PANTHER PTHR11079 33 277 2.5E-45 T 22-04-2016 L21SP4_RS04850 48c1399715b3317ef5be20e740a09288 281 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 122 136 - T 22-04-2016 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 L21SP4_RS04850 48c1399715b3317ef5be20e740a09288 281 Gene3D G3DSA:3.10.290.10 20 63 1.8E-5 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 L21SP4_RS04850 48c1399715b3317ef5be20e740a09288 281 Pfam PF00849 RNA pseudouridylate synthase 87 215 4.1E-25 T 22-04-2016 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 L21SP4_RS04850 48c1399715b3317ef5be20e740a09288 281 PANTHER PTHR11079:SF73 33 277 2.5E-45 T 22-04-2016 L21SP4_RS11540 4550670aad1ecf42f38af574c5fde0e8 1072 PANTHER PTHR11070 295 743 1.5E-63 T 22-04-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 L21SP4_RS11540 4550670aad1ecf42f38af574c5fde0e8 1072 PANTHER PTHR11070 785 806 1.5E-63 T 22-04-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 L21SP4_RS11540 4550670aad1ecf42f38af574c5fde0e8 1072 PANTHER PTHR11070 4 67 1.5E-63 T 22-04-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 L21SP4_RS11540 4550670aad1ecf42f38af574c5fde0e8 1072 PANTHER PTHR11070 94 178 1.5E-63 T 22-04-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 L21SP4_RS11540 4550670aad1ecf42f38af574c5fde0e8 1072 Gene3D G3DSA:3.40.50.300 330 454 6.4E-46 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS11540 4550670aad1ecf42f38af574c5fde0e8 1072 Gene3D G3DSA:3.40.50.300 102 164 6.4E-46 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS11540 4550670aad1ecf42f38af574c5fde0e8 1072 Gene3D G3DSA:3.40.50.300 4 54 6.4E-46 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS11540 4550670aad1ecf42f38af574c5fde0e8 1072 Gene3D G3DSA:3.40.50.300 701 811 1.5E-32 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS11540 4550670aad1ecf42f38af574c5fde0e8 1072 Gene3D G3DSA:3.40.50.300 464 578 1.5E-32 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS11540 4550670aad1ecf42f38af574c5fde0e8 1072 SUPERFAMILY SSF52540 3 58 6.28E-80 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS11540 4550670aad1ecf42f38af574c5fde0e8 1072 SUPERFAMILY SSF52540 320 742 6.28E-80 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS11540 4550670aad1ecf42f38af574c5fde0e8 1072 SUPERFAMILY SSF52540 94 197 6.28E-80 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS11540 4550670aad1ecf42f38af574c5fde0e8 1072 SUPERFAMILY SSF52540 786 810 6.28E-80 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS11540 4550670aad1ecf42f38af574c5fde0e8 1072 Pfam PF00580 UvrD/REP helicase N-terminal domain 5 452 2.3E-34 T 22-04-2016 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 L21SP4_RS11540 4550670aad1ecf42f38af574c5fde0e8 1072 SUPERFAMILY SSF52980 903 1051 3.97E-6 T 22-04-2016 IPR011335 Restriction endonuclease type II-like L21SP4_RS11540 4550670aad1ecf42f38af574c5fde0e8 1072 Pfam PF13361 UvrD-like helicase C-terminal domain 706 808 4.0E-12 T 22-04-2016 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 L21SP4_RS11540 4550670aad1ecf42f38af574c5fde0e8 1072 Pfam PF12705 PD-(D/E)XK nuclease superfamily 905 1043 6.0E-9 T 22-04-2016 L21SP4_RS07925 8522f529b966fad059f9e6aa24daff25 292 PANTHER PTHR11092:SF0 1 290 2.2E-86 T 22-04-2016 L21SP4_RS07925 8522f529b966fad059f9e6aa24daff25 292 PANTHER PTHR11092 1 290 2.2E-86 T 22-04-2016 IPR010099 Epimerase family protein SDR39U1 L21SP4_RS07925 8522f529b966fad059f9e6aa24daff25 292 Gene3D G3DSA:3.40.50.720 1 238 2.1E-23 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS07925 8522f529b966fad059f9e6aa24daff25 292 TIGRFAM TIGR01777 yfcH: TIGR01777 family protein 3 288 6.2E-76 T 22-04-2016 IPR010099 Epimerase family protein SDR39U1 L21SP4_RS07925 8522f529b966fad059f9e6aa24daff25 292 Pfam PF08338 Domain of unknown function (DUF1731) 244 289 1.2E-12 T 22-04-2016 IPR013549 Domain of unknown function DUF1731 L21SP4_RS07925 8522f529b966fad059f9e6aa24daff25 292 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 213 1.0E-13 T 22-04-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 L21SP4_RS07925 8522f529b966fad059f9e6aa24daff25 292 SUPERFAMILY SSF51735 1 244 5.04E-38 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS08880 5ad2ad8ae8cd0fea225a188a7d24d361 1028 SUPERFAMILY SSF55545 28 143 9.42E-10 T 22-04-2016 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like L21SP4_RS08880 5ad2ad8ae8cd0fea225a188a7d24d361 1028 SUPERFAMILY SSF49785 885 961 4.47E-14 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS08880 5ad2ad8ae8cd0fea225a188a7d24d361 1028 Gene3D G3DSA:3.30.379.10 25 141 1.2E-11 T 22-04-2016 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like L21SP4_RS08880 5ad2ad8ae8cd0fea225a188a7d24d361 1028 Gene3D G3DSA:2.60.120.260 887 961 6.1E-12 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS08880 5ad2ad8ae8cd0fea225a188a7d24d361 1028 Pfam PF00754 F5/8 type C domain 886 985 2.9E-11 T 22-04-2016 IPR000421 Coagulation factor 5/8 C-terminal domain L21SP4_RS11790 af9de5ace79e9acaa121fafc878339d7 895 SUPERFAMILY SSF49785 640 748 2.06E-12 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS11790 af9de5ace79e9acaa121fafc878339d7 895 Gene3D G3DSA:2.115.10.20 294 511 2.3E-13 T 22-04-2016 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP4_RS11790 af9de5ace79e9acaa121fafc878339d7 895 Pfam PF00754 F5/8 type C domain 641 745 1.7E-8 T 22-04-2016 IPR000421 Coagulation factor 5/8 C-terminal domain L21SP4_RS11790 af9de5ace79e9acaa121fafc878339d7 895 SUPERFAMILY SSF75005 293 530 3.0E-21 T 22-04-2016 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP4_RS11790 af9de5ace79e9acaa121fafc878339d7 895 Gene3D G3DSA:2.60.120.260 623 748 4.1E-11 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS10980 da188e41a4f28e2bc1a2918a95ca730e 1052 Pfam PF00593 TonB dependent receptor 762 1049 7.3E-24 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 L21SP4_RS10980 da188e41a4f28e2bc1a2918a95ca730e 1052 SUPERFAMILY SSF56935 674 721 2.86E-68 T 22-04-2016 L21SP4_RS10980 da188e41a4f28e2bc1a2918a95ca730e 1052 SUPERFAMILY SSF56935 755 1052 2.86E-68 T 22-04-2016 L21SP4_RS10980 da188e41a4f28e2bc1a2918a95ca730e 1052 SUPERFAMILY SSF56935 350 383 2.86E-68 T 22-04-2016 L21SP4_RS10980 da188e41a4f28e2bc1a2918a95ca730e 1052 SUPERFAMILY SSF56935 548 617 2.86E-68 T 22-04-2016 L21SP4_RS10980 da188e41a4f28e2bc1a2918a95ca730e 1052 SUPERFAMILY SSF56935 422 510 2.86E-68 T 22-04-2016 L21SP4_RS10980 da188e41a4f28e2bc1a2918a95ca730e 1052 SUPERFAMILY SSF56935 142 265 2.86E-68 T 22-04-2016 L21SP4_RS10980 da188e41a4f28e2bc1a2918a95ca730e 1052 Gene3D G3DSA:2.60.40.1120 31 108 7.0E-10 T 22-04-2016 IPR014766 Carboxypeptidase, regulatory domain L21SP4_RS10980 da188e41a4f28e2bc1a2918a95ca730e 1052 Pfam PF13620 Carboxypeptidase regulatory-like domain 31 108 8.2E-12 T 22-04-2016 L21SP4_RS10980 da188e41a4f28e2bc1a2918a95ca730e 1052 Gene3D G3DSA:2.40.170.20 423 619 3.5E-47 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 L21SP4_RS10980 da188e41a4f28e2bc1a2918a95ca730e 1052 Gene3D G3DSA:2.40.170.20 332 384 3.5E-47 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 L21SP4_RS10980 da188e41a4f28e2bc1a2918a95ca730e 1052 Gene3D G3DSA:2.40.170.20 675 713 3.5E-47 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 L21SP4_RS10980 da188e41a4f28e2bc1a2918a95ca730e 1052 Gene3D G3DSA:2.40.170.20 745 1052 3.5E-47 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 L21SP4_RS10980 da188e41a4f28e2bc1a2918a95ca730e 1052 Gene3D G3DSA:2.170.130.10 143 247 2.7E-9 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 L21SP4_RS10980 da188e41a4f28e2bc1a2918a95ca730e 1052 SUPERFAMILY SSF49452 26 107 7.26E-11 T 22-04-2016 IPR013784 Carbohydrate-binding-like fold GO:0030246 L21SP4_RS10980 da188e41a4f28e2bc1a2918a95ca730e 1052 Pfam PF07715 TonB-dependent Receptor Plug Domain 144 237 2.1E-7 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 L21SP4_RS03065 7056b88f58f7410ecc378d9456f30a3a 523 SUPERFAMILY SSF51445 40 397 6.4E-29 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily L21SP4_RS03065 7056b88f58f7410ecc378d9456f30a3a 523 Pfam PF12891 Glycoside hydrolase family 44 71 301 3.7E-67 T 22-04-2016 IPR024745 Glycoside hydrolase, family 44 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 L21SP4_RS06630 e49807c57bbdd0fc1f6cabd372ee4043 495 Pfam PF00884 Sulfatase 7 356 9.8E-52 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS06630 e49807c57bbdd0fc1f6cabd372ee4043 495 Gene3D G3DSA:3.40.720.10 5 365 2.4E-80 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS06630 e49807c57bbdd0fc1f6cabd372ee4043 495 ProSitePatterns PS00149 Sulfatases signature 2. 100 110 - T 22-04-2016 IPR024607 Sulfatase, conserved site L21SP4_RS06630 e49807c57bbdd0fc1f6cabd372ee4043 495 PANTHER PTHR10342 1 111 6.4E-77 T 22-04-2016 L21SP4_RS06630 e49807c57bbdd0fc1f6cabd372ee4043 495 PANTHER PTHR10342 252 470 6.4E-77 T 22-04-2016 L21SP4_RS06630 e49807c57bbdd0fc1f6cabd372ee4043 495 PANTHER PTHR10342 128 236 6.4E-77 T 22-04-2016 L21SP4_RS06630 e49807c57bbdd0fc1f6cabd372ee4043 495 Gene3D G3DSA:3.30.1120.10 388 447 4.7E-5 T 22-04-2016 L21SP4_RS06630 e49807c57bbdd0fc1f6cabd372ee4043 495 PANTHER PTHR10342:SF207 1 111 6.4E-77 T 22-04-2016 L21SP4_RS06630 e49807c57bbdd0fc1f6cabd372ee4043 495 PANTHER PTHR10342:SF207 252 470 6.4E-77 T 22-04-2016 L21SP4_RS06630 e49807c57bbdd0fc1f6cabd372ee4043 495 PANTHER PTHR10342:SF207 128 236 6.4E-77 T 22-04-2016 L21SP4_RS06630 e49807c57bbdd0fc1f6cabd372ee4043 495 SUPERFAMILY SSF53649 5 445 3.2E-98 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS04500 c258315034da50495a5b2ec891097973 991 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 500 642 1.6E-13 T 22-04-2016 L21SP4_RS04500 c258315034da50495a5b2ec891097973 991 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 239 312 9.7E-9 T 22-04-2016 L21SP4_RS04500 c258315034da50495a5b2ec891097973 991 SUPERFAMILY SSF75005 354 518 1.61E-18 T 22-04-2016 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP4_RS04500 c258315034da50495a5b2ec891097973 991 SUPERFAMILY SSF75005 708 813 5.23E-7 T 22-04-2016 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP4_RS04500 c258315034da50495a5b2ec891097973 991 SUPERFAMILY SSF49899 496 666 8.61E-17 T 22-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP4_RS04500 c258315034da50495a5b2ec891097973 991 Pfam PF00251 Glycosyl hydrolases family 32 N-terminal domain 355 460 3.8E-5 T 22-04-2016 IPR013148 Glycosyl hydrolase family 32, N-terminal L21SP4_RS04500 c258315034da50495a5b2ec891097973 991 SUPERFAMILY SSF49899 225 318 2.24E-12 T 22-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP4_RS04500 c258315034da50495a5b2ec891097973 991 Gene3D G3DSA:2.60.120.200 500 644 1.5E-10 T 22-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP4_RS04500 c258315034da50495a5b2ec891097973 991 Gene3D G3DSA:2.60.120.200 238 315 5.1E-13 T 22-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP4_RS08270 e2bee6792f1c922a849195dee7dd9d2e 126 SUPERFAMILY SSF64263 1 117 1.11E-43 T 22-04-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS08270 e2bee6792f1c922a849195dee7dd9d2e 126 PANTHER PTHR14413 1 117 2.2E-52 T 22-04-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS08270 e2bee6792f1c922a849195dee7dd9d2e 126 ProSitePatterns PS01167 Ribosomal protein L17 signature. 34 56 - T 22-04-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS08270 e2bee6792f1c922a849195dee7dd9d2e 126 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 116 24.913 T 22-04-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS08270 e2bee6792f1c922a849195dee7dd9d2e 126 Gene3D G3DSA:3.90.1030.10 1 117 7.3E-46 T 22-04-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS08270 e2bee6792f1c922a849195dee7dd9d2e 126 Pfam PF01196 Ribosomal protein L17 20 116 2.7E-33 T 22-04-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS08270 e2bee6792f1c922a849195dee7dd9d2e 126 TIGRFAM TIGR00059 L17: ribosomal protein bL17 9 117 4.7E-39 T 22-04-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS05925 165b2f3c92f77ed2de53736d36d18087 87 PANTHER PTHR38039 3 87 1.1E-12 T 22-04-2016 L21SP4_RS05925 165b2f3c92f77ed2de53736d36d18087 87 SUPERFAMILY SSF143011 2 87 1.11E-18 T 22-04-2016 L21SP4_RS05925 165b2f3c92f77ed2de53736d36d18087 87 Pfam PF06769 YoeB-like toxin of bacterial type II toxin-antitoxin system 24 86 1.2E-8 T 22-04-2016 IPR009614 Toxin YoeB GO:0004519|GO:0006401 L21SP4_RS05925 165b2f3c92f77ed2de53736d36d18087 87 PANTHER PTHR38039:SF1 3 87 1.1E-12 T 22-04-2016 L21SP4_RS05925 165b2f3c92f77ed2de53736d36d18087 87 TIGRFAM TIGR02116 toxin_Txe_YoeB: addiction module toxin, Txe/YoeB family 7 86 7.9E-27 T 22-04-2016 IPR009614 Toxin YoeB GO:0004519|GO:0006401 L21SP4_RS05925 165b2f3c92f77ed2de53736d36d18087 87 TIGRFAM TIGR02385 RelE_StbE: addiction module toxin, RelE/StbE family 4 85 5.0E-8 T 22-04-2016 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family L21SP4_RS03545 feddb9cae9d1b85277a860e5e855be21 150 Pfam PF12019 Type II transport protein GspH 32 141 8.3E-6 T 22-04-2016 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 L21SP4_RS03545 feddb9cae9d1b85277a860e5e855be21 150 SUPERFAMILY SSF54523 1 119 4.94E-5 T 22-04-2016 L21SP4_RS11800 8a7af84ed3cb6298aeed65d306573816 120 Pfam PF13657 HipA N-terminal domain 13 107 7.1E-20 T 22-04-2016 IPR017508 HipA, N-terminal subdomain 1 L21SP4_RS11800 8a7af84ed3cb6298aeed65d306573816 120 TIGRFAM TIGR03071 couple_hipA: HipA N-terminal domain 13 107 1.8E-18 T 22-04-2016 IPR017508 HipA, N-terminal subdomain 1 L21SP4_RS00055 8df72f16a841a9a1ed9f2b125848547c 385 Pfam PF13286 Phosphohydrolase-associated domain 288 373 7.7E-18 T 22-04-2016 IPR026875 Phosphohydrolase-associated domain L21SP4_RS00055 8df72f16a841a9a1ed9f2b125848547c 385 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 38 170 6.6E-54 T 22-04-2016 IPR006261 Deoxyguanosinetriphosphate triphosphohydrolase GO:0000287|GO:0008832|GO:0046039 L21SP4_RS00055 8df72f16a841a9a1ed9f2b125848547c 385 PANTHER PTHR11373:SF25 1 172 5.1E-81 T 22-04-2016 L21SP4_RS00055 8df72f16a841a9a1ed9f2b125848547c 385 Gene3D G3DSA:1.10.3210.10 35 224 9.1E-67 T 22-04-2016 IPR006674 HD domain L21SP4_RS00055 8df72f16a841a9a1ed9f2b125848547c 385 Gene3D G3DSA:1.10.3210.10 279 375 9.1E-67 T 22-04-2016 IPR006674 HD domain L21SP4_RS00055 8df72f16a841a9a1ed9f2b125848547c 385 SMART SM00471 71 211 3.2E-10 T 22-04-2016 IPR003607 HD/PDEase domain L21SP4_RS00055 8df72f16a841a9a1ed9f2b125848547c 385 SUPERFAMILY SSF109604 27 374 2.24E-69 T 22-04-2016 L21SP4_RS00055 8df72f16a841a9a1ed9f2b125848547c 385 PANTHER PTHR11373 1 172 5.1E-81 T 22-04-2016 L21SP4_RS00055 8df72f16a841a9a1ed9f2b125848547c 385 Hamap MF_01212 Deoxyguanosinetriphosphate triphosphohydrolase-like protein. 15 377 33.046 T 22-04-2016 IPR023023 Deoxyguanosinetriphosphate triphosphohydrolase, type 2 L21SP4_RS00055 8df72f16a841a9a1ed9f2b125848547c 385 Pfam PF01966 HD domain 75 199 2.0E-13 T 22-04-2016 IPR006674 HD domain L21SP4_RS11140 212b572f767c05ac43c29b365a9e864b 388 Pfam PF13439 Glycosyltransferase Family 4 25 190 1.4E-12 T 22-04-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain L21SP4_RS11140 212b572f767c05ac43c29b365a9e864b 388 PANTHER PTHR12526 53 386 1.0E-47 T 22-04-2016 L21SP4_RS11140 212b572f767c05ac43c29b365a9e864b 388 Gene3D G3DSA:3.40.50.2000 202 363 2.2E-16 T 22-04-2016 L21SP4_RS11140 212b572f767c05ac43c29b365a9e864b 388 Pfam PF00534 Glycosyl transferases group 1 205 362 1.4E-21 T 22-04-2016 IPR001296 Glycosyl transferase, family 1 L21SP4_RS11140 212b572f767c05ac43c29b365a9e864b 388 SUPERFAMILY SSF53756 23 385 2.92E-62 T 22-04-2016 L21SP4_RS06265 36ea06031a92c5e5d0e12c8a6dfd3ebb 173 ProDom PD181473 CT309 TC0583 CPN0087/CP0687/CPJ0087/CPB0087 105 165 0.002 T 22-04-2016 L21SP4_RS06265 36ea06031a92c5e5d0e12c8a6dfd3ebb 173 Pfam PF10962 Protein of unknown function (DUF2764) 105 166 1.3E-7 T 22-04-2016 IPR024492 Protein of unknown function DUF2764 L21SP4_RS06100 7b3cdcc56eb38cd0bff8441fb2743af4 245 Pfam PF02397 Bacterial sugar transferase 51 239 3.9E-58 T 22-04-2016 IPR003362 Bacterial sugar transferase L21SP4_RS06100 7b3cdcc56eb38cd0bff8441fb2743af4 245 PANTHER PTHR30576 4 245 4.2E-94 T 22-04-2016 L21SP4_RS11200 96642b239abf5826badc9c3141e2a62b 297 SUPERFAMILY SSF52540 2 37 8.5E-22 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS11200 96642b239abf5826badc9c3141e2a62b 297 SUPERFAMILY SSF52540 156 263 8.5E-22 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS11200 96642b239abf5826badc9c3141e2a62b 297 Gene3D G3DSA:3.40.50.300 147 261 5.1E-11 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS11200 96642b239abf5826badc9c3141e2a62b 297 Gene3D G3DSA:3.40.50.300 5 50 5.1E-11 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS11200 96642b239abf5826badc9c3141e2a62b 297 Pfam PF13469 Sulfotransferase family 4 258 1.4E-20 T 22-04-2016 L21SP4_RS00195 c4a50ad7efd2f53be7cb9a322d993eec 199 PANTHER PTHR10093:SF1 1 151 4.1E-48 T 22-04-2016 L21SP4_RS00195 c4a50ad7efd2f53be7cb9a322d993eec 199 SUPERFAMILY SSF82649 3 130 7.33E-34 T 22-04-2016 L21SP4_RS00195 c4a50ad7efd2f53be7cb9a322d993eec 199 Pfam PF04324 BFD-like [2Fe-2S] binding domain 142 189 1.4E-12 T 22-04-2016 IPR007419 BFD-like [2Fe-2S]-binding domain L21SP4_RS00195 c4a50ad7efd2f53be7cb9a322d993eec 199 Gene3D G3DSA:3.90.1010.10 4 130 1.4E-36 T 22-04-2016 L21SP4_RS00195 c4a50ad7efd2f53be7cb9a322d993eec 199 Pfam PF01592 NifU-like N terminal domain 5 129 1.6E-40 T 22-04-2016 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 L21SP4_RS00195 c4a50ad7efd2f53be7cb9a322d993eec 199 PANTHER PTHR10093 1 151 4.1E-48 T 22-04-2016 L21SP4_RS10065 cda88f1c3571add38fc1fddc3589a93a 146 Pfam PF13499 EF-hand domain pair 40 113 7.7E-8 T 22-04-2016 IPR002048 EF-hand domain GO:0005509 L21SP4_RS10065 cda88f1c3571add38fc1fddc3589a93a 146 Gene3D G3DSA:1.10.238.10 41 126 1.2E-9 T 22-04-2016 IPR011992 EF-hand domain pair L21SP4_RS10065 cda88f1c3571add38fc1fddc3589a93a 146 ProSitePatterns PS00018 EF-hand calcium-binding domain. 49 61 - T 22-04-2016 IPR018247 EF-Hand 1, calcium-binding site L21SP4_RS10065 cda88f1c3571add38fc1fddc3589a93a 146 SUPERFAMILY SSF47473 36 135 1.18E-10 T 22-04-2016 IPR011992 EF-hand domain pair L21SP4_RS00565 2f0cc6bb1ca447821d1590968f92a04f 71 SUPERFAMILY SSF53383 20 70 4.89E-9 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase L21SP4_RS00565 2f0cc6bb1ca447821d1590968f92a04f 71 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 23 68 4.6E-7 T 22-04-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 L21SP4_RS00565 2f0cc6bb1ca447821d1590968f92a04f 71 Gene3D G3DSA:3.90.1150.10 20 71 1.5E-10 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 L21SP4_RS07920 2b3d1d159cd21d52d2ec50ff4e4e4c0c 340 Pfam PF00069 Protein kinase domain 17 275 9.4E-35 T 22-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 L21SP4_RS07920 2b3d1d159cd21d52d2ec50ff4e4e4c0c 340 Gene3D G3DSA:3.30.200.20 11 85 1.2E-14 T 22-04-2016 L21SP4_RS07920 2b3d1d159cd21d52d2ec50ff4e4e4c0c 340 Gene3D G3DSA:1.10.510.10 86 286 1.5E-39 T 22-04-2016 L21SP4_RS07920 2b3d1d159cd21d52d2ec50ff4e4e4c0c 340 SUPERFAMILY SSF56112 9 293 7.27E-59 T 22-04-2016 IPR011009 Protein kinase-like domain L21SP4_RS07920 2b3d1d159cd21d52d2ec50ff4e4e4c0c 340 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 150 162 - T 22-04-2016 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 L21SP4_RS07920 2b3d1d159cd21d52d2ec50ff4e4e4c0c 340 PANTHER PTHR24362:SF160 16 339 2.3E-63 T 22-04-2016 L21SP4_RS07920 2b3d1d159cd21d52d2ec50ff4e4e4c0c 340 PANTHER PTHR24362 16 339 2.3E-63 T 22-04-2016 L21SP4_RS10345 d413d72ca9bbb2307f41a0b449090db4 288 ProSitePatterns PS00770 Aminotransferases class-IV signature. 182 211 - T 22-04-2016 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: REACT_13 L21SP4_RS10345 d413d72ca9bbb2307f41a0b449090db4 288 PANTHER PTHR11825:SF7 3 281 5.4E-117 T 22-04-2016 L21SP4_RS10345 d413d72ca9bbb2307f41a0b449090db4 288 SUPERFAMILY SSF56752 2 280 2.22E-95 T 22-04-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 L21SP4_RS10345 d413d72ca9bbb2307f41a0b449090db4 288 Gene3D G3DSA:3.20.10.10 121 281 2.9E-54 T 22-04-2016 L21SP4_RS10345 d413d72ca9bbb2307f41a0b449090db4 288 TIGRFAM TIGR01122 ilvE_I: branched-chain amino acid aminotransferase 4 282 8.0E-103 T 22-04-2016 IPR005785 Branched-chain amino acid aminotransferase I GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|UniPathway: UPA00047|UniPathway: UPA00048|UniPathway: UPA00049 L21SP4_RS10345 d413d72ca9bbb2307f41a0b449090db4 288 Gene3D G3DSA:3.30.470.10 3 115 1.2E-45 T 22-04-2016 L21SP4_RS10345 d413d72ca9bbb2307f41a0b449090db4 288 PANTHER PTHR11825 3 281 5.4E-117 T 22-04-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 L21SP4_RS10345 d413d72ca9bbb2307f41a0b449090db4 288 Pfam PF01063 Amino-transferase class IV 29 256 7.4E-56 T 22-04-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 L21SP4_RS01945 fe2df97376fc4f6cf800623f0f112146 274 SUPERFAMILY SSF46689 221 271 3.81E-14 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS01945 fe2df97376fc4f6cf800623f0f112146 274 SMART SM00342 184 267 1.5E-27 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP4_RS01945 fe2df97376fc4f6cf800623f0f112146 274 Gene3D G3DSA:1.10.10.60 169 220 6.1E-11 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS01945 fe2df97376fc4f6cf800623f0f112146 274 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 221 263 - T 22-04-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 L21SP4_RS01945 fe2df97376fc4f6cf800623f0f112146 274 Pfam PF12833 Helix-turn-helix domain 192 269 1.7E-22 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP4_RS01945 fe2df97376fc4f6cf800623f0f112146 274 SUPERFAMILY SSF51215 17 91 1.44E-6 T 22-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 L21SP4_RS01945 fe2df97376fc4f6cf800623f0f112146 274 PANTHER PTHR11019 152 274 1.2E-29 T 22-04-2016 L21SP4_RS01945 fe2df97376fc4f6cf800623f0f112146 274 PANTHER PTHR11019 16 130 1.2E-29 T 22-04-2016 L21SP4_RS01945 fe2df97376fc4f6cf800623f0f112146 274 SUPERFAMILY SSF46689 170 217 3.49E-5 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS01945 fe2df97376fc4f6cf800623f0f112146 274 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 236 251 3.2E-5 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 L21SP4_RS01945 fe2df97376fc4f6cf800623f0f112146 274 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 251 267 3.2E-5 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 L21SP4_RS01945 fe2df97376fc4f6cf800623f0f112146 274 Gene3D G3DSA:1.10.10.60 221 269 4.4E-18 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS01945 fe2df97376fc4f6cf800623f0f112146 274 Gene3D G3DSA:2.60.120.10 25 83 7.7E-5 T 22-04-2016 IPR014710 RmlC-like jelly roll fold L21SP4_RS00685 9503dfa49230a5fe86b9d06a6bc6c0cb 74 Gene3D G3DSA:3.30.70.1290 5 58 6.8E-7 T 22-04-2016 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 L21SP4_RS00685 9503dfa49230a5fe86b9d06a6bc6c0cb 74 Pfam PF01797 Transposase IS200 like 4 71 2.9E-8 T 22-04-2016 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 L21SP4_RS00685 9503dfa49230a5fe86b9d06a6bc6c0cb 74 SUPERFAMILY SSF143422 2 63 2.49E-11 T 22-04-2016 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 L21SP4_RS10385 97df13a959336d3cbe705f5be2e2bac7 193 PANTHER PTHR34475:SF1 1 101 1.9E-23 T 22-04-2016 L21SP4_RS10385 97df13a959336d3cbe705f5be2e2bac7 193 SUPERFAMILY SSF47413 2 71 3.75E-5 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 L21SP4_RS10385 97df13a959336d3cbe705f5be2e2bac7 193 Gene3D G3DSA:1.10.260.40 3 85 7.1E-7 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 L21SP4_RS10385 97df13a959336d3cbe705f5be2e2bac7 193 Pfam PF13413 Helix-turn-helix domain 7 67 2.3E-21 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 L21SP4_RS10385 97df13a959336d3cbe705f5be2e2bac7 193 PANTHER PTHR34475 1 101 1.9E-23 T 22-04-2016 L21SP4_RS05895 6622ace994e54b3bc98c0af09fbf9ef9 304 PANTHER PTHR30160 8 257 4.2E-25 T 22-04-2016 L21SP4_RS05895 6622ace994e54b3bc98c0af09fbf9ef9 304 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 129 257 8.2E-25 T 22-04-2016 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 L21SP4_RS05895 6622ace994e54b3bc98c0af09fbf9ef9 304 Gene3D G3DSA:3.40.50.2000 4 98 5.2E-10 T 22-04-2016 L21SP4_RS05895 6622ace994e54b3bc98c0af09fbf9ef9 304 PANTHER PTHR30160:SF7 8 257 4.2E-25 T 22-04-2016 L21SP4_RS05895 6622ace994e54b3bc98c0af09fbf9ef9 304 Gene3D G3DSA:3.40.50.2000 128 260 7.7E-35 T 22-04-2016 L21SP4_RS05895 6622ace994e54b3bc98c0af09fbf9ef9 304 SUPERFAMILY SSF53756 7 266 8.89E-49 T 22-04-2016 L21SP4_RS08700 8f5c32621fa3a929bc70beccdd7a6963 458 TIGRFAM TIGR00933 2a38: potassium uptake protein, TrkH family 34 430 3.4E-104 T 22-04-2016 IPR004772 TrkH potassium transport family GO:0016021|GO:0022820|GO:0071805 L21SP4_RS08700 8f5c32621fa3a929bc70beccdd7a6963 458 PANTHER PTHR32024 2 458 1.4E-166 T 22-04-2016 L21SP4_RS08700 8f5c32621fa3a929bc70beccdd7a6963 458 Pfam PF02386 Cation transport protein 40 441 9.3E-60 T 22-04-2016 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 L21SP4_RS08700 8f5c32621fa3a929bc70beccdd7a6963 458 PANTHER PTHR32024:SF1 2 458 1.4E-166 T 22-04-2016 L21SP4_RS08965 85a703489442a79d843678b1a6881a35 280 Pfam PF01261 Xylose isomerase-like TIM barrel 43 226 3.1E-20 T 22-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain L21SP4_RS08965 85a703489442a79d843678b1a6881a35 280 Gene3D G3DSA:3.20.20.150 13 277 5.8E-39 T 22-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain L21SP4_RS08965 85a703489442a79d843678b1a6881a35 280 PANTHER PTHR12110 1 250 2.5E-22 T 22-04-2016 L21SP4_RS08965 85a703489442a79d843678b1a6881a35 280 SUPERFAMILY SSF51658 10 255 8.51E-36 T 22-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain L21SP4_RS01085 223e28d33c8876f97f3fe00877c61d08 598 Pfam PF01566 Natural resistance-associated macrophage protein 257 533 6.1E-12 T 22-04-2016 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: REACT_15518 L21SP4_RS02570 9ed9aef80ef8e6785a57a4016ee2590d 492 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 193 483 6.6E-67 T 22-04-2016 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 L21SP4_RS02570 9ed9aef80ef8e6785a57a4016ee2590d 492 PANTHER PTHR11061 4 141 4.4E-146 T 22-04-2016 L21SP4_RS02570 9ed9aef80ef8e6785a57a4016ee2590d 492 PANTHER PTHR11061 178 490 4.4E-146 T 22-04-2016 L21SP4_RS02570 9ed9aef80ef8e6785a57a4016ee2590d 492 SUPERFAMILY SSF53335 189 490 6.44E-69 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS02570 9ed9aef80ef8e6785a57a4016ee2590d 492 SUPERFAMILY SSF53335 69 136 6.44E-69 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS02570 9ed9aef80ef8e6785a57a4016ee2590d 492 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 281 490 4.3E-17 T 22-04-2016 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 L21SP4_RS02570 9ed9aef80ef8e6785a57a4016ee2590d 492 PANTHER PTHR11061:SF30 4 141 4.4E-146 T 22-04-2016 L21SP4_RS02570 9ed9aef80ef8e6785a57a4016ee2590d 492 PANTHER PTHR11061:SF30 178 490 4.4E-146 T 22-04-2016 L21SP4_RS02570 9ed9aef80ef8e6785a57a4016ee2590d 492 Gene3D G3DSA:2.40.50.140 3 80 1.9E-19 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold L21SP4_RS02570 9ed9aef80ef8e6785a57a4016ee2590d 492 SUPERFAMILY SSF50249 4 60 6.28E-5 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold L21SP4_RS02570 9ed9aef80ef8e6785a57a4016ee2590d 492 Pfam PF01938 TRAM domain 7 58 7.5E-6 T 22-04-2016 IPR002792 TRAM domain L21SP4_RS02570 9ed9aef80ef8e6785a57a4016ee2590d 492 Gene3D G3DSA:3.40.50.150 287 489 3.1E-60 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS02570 9ed9aef80ef8e6785a57a4016ee2590d 492 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 473 483 - T 22-04-2016 IPR030391 RNA methyltransferase TrmA, conserved site L21SP4_RS02570 9ed9aef80ef8e6785a57a4016ee2590d 492 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 420 451 - T 22-04-2016 IPR030390 RNA methyltransferase TrmA, active site L21SP4_RS08760 de082b1f0ab0a50403296c10445dfc19 237 Pfam PF04367 Protein of unknown function (DUF502) 65 173 1.3E-27 T 22-04-2016 IPR007462 Protein of unknown function DUF502 L21SP4_RS08760 de082b1f0ab0a50403296c10445dfc19 237 PANTHER PTHR31876 8 230 3.6E-42 T 22-04-2016 L21SP4_RS08760 de082b1f0ab0a50403296c10445dfc19 237 PANTHER PTHR31876:SF1 8 230 3.6E-42 T 22-04-2016 L21SP4_RS07120 1356cb008ebe14cddb0714c272fcb16d 205 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 6 201 22.978 T 22-04-2016 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|UniPathway: UPA00241 L21SP4_RS07120 1356cb008ebe14cddb0714c272fcb16d 205 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 8 191 1.0E-40 T 22-04-2016 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|UniPathway: UPA00241 L21SP4_RS07120 1356cb008ebe14cddb0714c272fcb16d 205 PANTHER PTHR10695 7 200 9.9E-52 T 22-04-2016 L21SP4_RS07120 1356cb008ebe14cddb0714c272fcb16d 205 SUPERFAMILY SSF52540 8 196 8.88E-26 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS07120 1356cb008ebe14cddb0714c272fcb16d 205 Gene3D G3DSA:3.40.50.300 7 201 2.6E-56 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS07120 1356cb008ebe14cddb0714c272fcb16d 205 Pfam PF01121 Dephospho-CoA kinase 7 184 2.7E-39 T 22-04-2016 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|UniPathway: UPA00241 L21SP4_RS05190 2069a5082c77e5e70374b7f6fae2d6f9 378 Gene3D G3DSA:1.10.8.60 163 241 4.6E-8 T 22-04-2016 L21SP4_RS05190 2069a5082c77e5e70374b7f6fae2d6f9 378 PANTHER PTHR34388 304 377 1.0E-20 T 22-04-2016 L21SP4_RS05190 2069a5082c77e5e70374b7f6fae2d6f9 378 PANTHER PTHR34388 15 281 1.0E-20 T 22-04-2016 L21SP4_RS05190 2069a5082c77e5e70374b7f6fae2d6f9 378 SUPERFAMILY SSF48019 226 366 7.65E-6 T 22-04-2016 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: REACT_152|Reactome: REACT_1538|Reactome: REACT_216|Reactome: REACT_22172|Reactome: REACT_383 L21SP4_RS12030 651cd59a08337424688a0f7af7ba03f3 282 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 9 168 3.3E-22 T 22-04-2016 IPR000477 Reverse transcriptase domain L21SP4_RS12030 651cd59a08337424688a0f7af7ba03f3 282 PANTHER PTHR19446 15 204 6.1E-31 T 22-04-2016 L21SP4_RS12030 651cd59a08337424688a0f7af7ba03f3 282 PANTHER PTHR19446:SF383 15 204 6.1E-31 T 22-04-2016 L21SP4_RS12030 651cd59a08337424688a0f7af7ba03f3 282 Pfam PF08388 Group II intron, maturase-specific domain 193 260 1.3E-14 T 22-04-2016 IPR013597 Group II intron, maturase-specific L21SP4_RS12030 651cd59a08337424688a0f7af7ba03f3 282 SUPERFAMILY SSF56672 13 181 1.4E-26 T 22-04-2016 L21SP4_RS08705 633ff848e7967c4b048f481deb0cbf7d 217 Gene3D G3DSA:3.40.50.720 2 138 9.6E-35 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS08705 633ff848e7967c4b048f481deb0cbf7d 217 Gene3D G3DSA:3.30.70.1450 144 216 1.6E-16 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 L21SP4_RS08705 633ff848e7967c4b048f481deb0cbf7d 217 SUPERFAMILY SSF116726 131 216 1.31E-18 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 L21SP4_RS08705 633ff848e7967c4b048f481deb0cbf7d 217 SUPERFAMILY SSF51735 3 134 4.99E-30 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS08705 633ff848e7967c4b048f481deb0cbf7d 217 PANTHER PTHR16254 2 158 6.7E-42 T 22-04-2016 L21SP4_RS08705 633ff848e7967c4b048f481deb0cbf7d 217 Pfam PF02254 TrkA-N domain 4 119 6.6E-23 T 22-04-2016 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 L21SP4_RS08705 633ff848e7967c4b048f481deb0cbf7d 217 Pfam PF02080 TrkA-C domain 151 216 3.7E-12 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 L21SP4_RS02635 aae81fb86166dd3890a05d41fd05bcba 524 Gene3D G3DSA:3.40.50.970 2 178 3.2E-52 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold L21SP4_RS02635 aae81fb86166dd3890a05d41fd05bcba 524 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 16 176 5.2E-11 T 22-04-2016 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 L21SP4_RS02635 aae81fb86166dd3890a05d41fd05bcba 524 SUPERFAMILY SSF52518 332 515 4.71E-27 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold L21SP4_RS02635 aae81fb86166dd3890a05d41fd05bcba 524 PIRSF PIRSF006439 1 524 2.4E-177 T 22-04-2016 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 L21SP4_RS02635 aae81fb86166dd3890a05d41fd05bcba 524 PANTHER PTHR18968:SF91 310 512 4.5E-41 T 22-04-2016 L21SP4_RS02635 aae81fb86166dd3890a05d41fd05bcba 524 PANTHER PTHR18968 310 512 4.5E-41 T 22-04-2016 L21SP4_RS02635 aae81fb86166dd3890a05d41fd05bcba 524 SUPERFAMILY SSF52518 4 233 2.42E-53 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold L21SP4_RS02635 aae81fb86166dd3890a05d41fd05bcba 524 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 358 505 1.1E-21 T 22-04-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 L21SP4_RS02635 aae81fb86166dd3890a05d41fd05bcba 524 Gene3D G3DSA:3.40.50.970 330 518 6.3E-23 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold L21SP4_RS03550 fa9626fdc74f918daee074a61796a120 130 Pfam PF13633 Prokaryotic N-terminal methylation site 9 30 2.0E-5 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site L21SP4_RS03550 fa9626fdc74f918daee074a61796a120 130 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 9 29 - T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site L21SP4_RS03550 fa9626fdc74f918daee074a61796a120 130 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 8 31 1.7E-6 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site L21SP4_RS02540 a501c9fc3a9abdd52c276a037d079211 174 Pfam PF13662 Toprim domain 57 146 6.0E-17 T 22-04-2016 IPR006171 Toprim domain L21SP4_RS02540 a501c9fc3a9abdd52c276a037d079211 174 Hamap MF_00017 Recombination protein RecR [recR]. 1 173 68.987 T 22-04-2016 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 L21SP4_RS02540 a501c9fc3a9abdd52c276a037d079211 174 SUPERFAMILY SSF111304 2 173 3.53E-48 T 22-04-2016 IPR023627 Recombination protein RecR L21SP4_RS02540 a501c9fc3a9abdd52c276a037d079211 174 Pfam PF02132 RecR protein 13 53 7.7E-11 T 22-04-2016 IPR023628 Recombination protein RecR, C4-type zinc finger L21SP4_RS02540 a501c9fc3a9abdd52c276a037d079211 174 PANTHER PTHR30446 1 174 2.6E-59 T 22-04-2016 L21SP4_RS02540 a501c9fc3a9abdd52c276a037d079211 174 SMART SM00493 55 140 4.1E-6 T 22-04-2016 IPR006171 Toprim domain L21SP4_RS02540 a501c9fc3a9abdd52c276a037d079211 174 PANTHER PTHR30446:SF0 1 174 2.6E-59 T 22-04-2016 L21SP4_RS06320 0c6a4df8f53df5b4696e2b9168b0f78a 706 Gene3D G3DSA:3.10.50.30 622 687 6.6E-6 T 22-04-2016 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 L21SP4_RS06320 0c6a4df8f53df5b4696e2b9168b0f78a 706 SUPERFAMILY SSF54534 622 686 3.79E-6 T 22-04-2016 L21SP4_RS06320 0c6a4df8f53df5b4696e2b9168b0f78a 706 Pfam PF03449 Transcription elongation factor, N-terminal 543 605 7.6E-18 T 22-04-2016 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 L21SP4_RS06320 0c6a4df8f53df5b4696e2b9168b0f78a 706 SUPERFAMILY SSF46557 539 611 3.4E-19 T 22-04-2016 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 L21SP4_RS06320 0c6a4df8f53df5b4696e2b9168b0f78a 706 PANTHER PTHR30437 129 696 2.7E-23 T 22-04-2016 L21SP4_RS06320 0c6a4df8f53df5b4696e2b9168b0f78a 706 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 622 687 2.5E-7 T 22-04-2016 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 L21SP4_RS06320 0c6a4df8f53df5b4696e2b9168b0f78a 706 Gene3D G3DSA:1.10.287.180 540 605 3.7E-20 T 22-04-2016 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 L21SP4_RS06595 f5e29f8f635456c2439b1ed3fa01e1ac 369 PANTHER PTHR33619:SF3 1 365 3.2E-23 T 22-04-2016 L21SP4_RS06595 f5e29f8f635456c2439b1ed3fa01e1ac 369 Pfam PF10531 SLBB domain 179 217 1.0E-5 T 22-04-2016 IPR019554 Soluble ligand binding domain L21SP4_RS06595 f5e29f8f635456c2439b1ed3fa01e1ac 369 Pfam PF10531 SLBB domain 256 298 3.8E-8 T 22-04-2016 IPR019554 Soluble ligand binding domain L21SP4_RS06595 f5e29f8f635456c2439b1ed3fa01e1ac 369 Gene3D G3DSA:3.30.1950.10 85 154 2.6E-11 T 22-04-2016 L21SP4_RS06595 f5e29f8f635456c2439b1ed3fa01e1ac 369 Gene3D G3DSA:3.10.560.10 155 247 4.3E-12 T 22-04-2016 L21SP4_RS06595 f5e29f8f635456c2439b1ed3fa01e1ac 369 Gene3D G3DSA:3.10.560.10 250 335 1.3E-15 T 22-04-2016 L21SP4_RS06595 f5e29f8f635456c2439b1ed3fa01e1ac 369 Pfam PF02563 Polysaccharide biosynthesis/export protein 76 155 2.8E-12 T 22-04-2016 IPR003715 Polysaccharide export protein GO:0015159|GO:0015774|GO:0016020 L21SP4_RS06595 f5e29f8f635456c2439b1ed3fa01e1ac 369 PANTHER PTHR33619 1 365 3.2E-23 T 22-04-2016 L21SP4_RS02145 bd9157ad03e7fda763f865fb3c1c5f30 133 Pfam PF00380 Ribosomal protein S9/S16 13 133 2.0E-45 T 22-04-2016 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 L21SP4_RS02145 bd9157ad03e7fda763f865fb3c1c5f30 133 PANTHER PTHR21569 4 133 4.8E-59 T 22-04-2016 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 L21SP4_RS02145 bd9157ad03e7fda763f865fb3c1c5f30 133 ProSitePatterns PS00360 Ribosomal protein S9 signature. 72 90 - T 22-04-2016 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 L21SP4_RS02145 bd9157ad03e7fda763f865fb3c1c5f30 133 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 4 133 28.366 T 22-04-2016 IPR023035 Ribosomal protein S9, bacterial/plastid L21SP4_RS02145 bd9157ad03e7fda763f865fb3c1c5f30 133 Gene3D G3DSA:3.30.230.10 8 133 1.2E-47 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup L21SP4_RS02145 bd9157ad03e7fda763f865fb3c1c5f30 133 PANTHER PTHR21569:SF1 4 133 4.8E-59 T 22-04-2016 L21SP4_RS02145 bd9157ad03e7fda763f865fb3c1c5f30 133 SUPERFAMILY SSF54211 9 133 2.77E-43 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold L21SP4_RS03460 9384c2a5c6d17b67637ec9f5486d6bc8 802 Pfam PF02086 D12 class N6 adenine-specific DNA methyltransferase 53 338 4.0E-28 T 22-04-2016 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 L21SP4_RS03460 9384c2a5c6d17b67637ec9f5486d6bc8 802 Gene3D G3DSA:3.40.50.150 50 105 1.9E-23 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS03460 9384c2a5c6d17b67637ec9f5486d6bc8 802 Gene3D G3DSA:3.40.50.150 232 374 1.9E-23 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS03460 9384c2a5c6d17b67637ec9f5486d6bc8 802 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 53 69 1.3E-7 T 22-04-2016 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 L21SP4_RS03460 9384c2a5c6d17b67637ec9f5486d6bc8 802 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 246 258 1.3E-7 T 22-04-2016 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 L21SP4_RS03460 9384c2a5c6d17b67637ec9f5486d6bc8 802 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 75 89 1.3E-7 T 22-04-2016 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 L21SP4_RS03460 9384c2a5c6d17b67637ec9f5486d6bc8 802 SUPERFAMILY SSF53335 50 337 1.67E-32 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS03460 9384c2a5c6d17b67637ec9f5486d6bc8 802 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 249 255 - T 22-04-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 L21SP4_RS03460 9384c2a5c6d17b67637ec9f5486d6bc8 802 Gene3D G3DSA:1.20.5.170 639 665 7.0E-4 T 22-04-2016 L21SP4_RS11275 29a6c9243c2c05e0d6b183b70af0f052 359 SUPERFAMILY SSF53756 28 354 4.32E-45 T 22-04-2016 L21SP4_RS11275 29a6c9243c2c05e0d6b183b70af0f052 359 Pfam PF13439 Glycosyltransferase Family 4 22 174 5.9E-10 T 22-04-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain L21SP4_RS11275 29a6c9243c2c05e0d6b183b70af0f052 359 Gene3D G3DSA:3.40.50.2000 163 338 5.4E-12 T 22-04-2016 L21SP4_RS11275 29a6c9243c2c05e0d6b183b70af0f052 359 Pfam PF00534 Glycosyl transferases group 1 178 336 4.1E-18 T 22-04-2016 IPR001296 Glycosyl transferase, family 1 L21SP4_RS11275 29a6c9243c2c05e0d6b183b70af0f052 359 PANTHER PTHR12526 78 356 3.0E-25 T 22-04-2016 L21SP4_RS10830 ca1ede2ffad85d658733dbf1375451da 301 PANTHER PTHR10655 18 196 8.9E-38 T 22-04-2016 L21SP4_RS10830 ca1ede2ffad85d658733dbf1375451da 301 Pfam PF10503 Esterase PHB depolymerase 32 179 5.0E-11 T 22-04-2016 IPR010126 Esterase, PHB depolymerase GO:0005576 L21SP4_RS10830 ca1ede2ffad85d658733dbf1375451da 301 SUPERFAMILY SSF53474 245 281 1.77E-30 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold L21SP4_RS10830 ca1ede2ffad85d658733dbf1375451da 301 SUPERFAMILY SSF53474 20 195 1.77E-30 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold L21SP4_RS10830 ca1ede2ffad85d658733dbf1375451da 301 Gene3D G3DSA:3.40.50.1820 14 299 1.3E-43 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold L21SP4_RS10830 ca1ede2ffad85d658733dbf1375451da 301 PANTHER PTHR10655:SF33 18 196 8.9E-38 T 22-04-2016 L21SP4_RS03555 4e5f0969eb15b17c2a19a86798329187 238 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 12 32 - T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site L21SP4_RS03555 4e5f0969eb15b17c2a19a86798329187 238 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 12 33 7.7E-5 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site L21SP4_RS10250 2a772e04758da206d588a4f516536d23 518 SMART SM00729 208 420 5.1E-19 T 22-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 L21SP4_RS10250 2a772e04758da206d588a4f516536d23 518 Gene3D G3DSA:3.80.30.20 219 417 7.7E-31 T 22-04-2016 IPR023404 Radical SAM, alpha/beta horseshoe L21SP4_RS10250 2a772e04758da206d588a4f516536d23 518 Pfam PF04055 Radical SAM superfamily 218 375 2.0E-16 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 L21SP4_RS10250 2a772e04758da206d588a4f516536d23 518 PANTHER PTHR11918 85 380 1.8E-32 T 22-04-2016 IPR023970 Methylthiotransferase/radical SAM-type protein L21SP4_RS10250 2a772e04758da206d588a4f516536d23 518 SUPERFAMILY SSF102114 219 405 2.35E-30 T 22-04-2016 L21SP4_RS02930 5c39dd16fcafb5e39f4692cd6ecdc728 163 SMART SM00855 3 114 8.2E-9 T 22-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 L21SP4_RS02930 5c39dd16fcafb5e39f4692cd6ecdc728 163 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 5 79 2.0E-13 T 22-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 L21SP4_RS02930 5c39dd16fcafb5e39f4692cd6ecdc728 163 Gene3D G3DSA:3.40.50.1240 1 160 8.8E-41 T 22-04-2016 IPR029033 Histidine phosphatase superfamily L21SP4_RS02930 5c39dd16fcafb5e39f4692cd6ecdc728 163 PANTHER PTHR23029 1 80 2.8E-15 T 22-04-2016 L21SP4_RS02930 5c39dd16fcafb5e39f4692cd6ecdc728 163 SUPERFAMILY SSF53254 1 150 1.01E-25 T 22-04-2016 IPR029033 Histidine phosphatase superfamily L21SP4_RS02810 58dc7972c2ae6dbbbf88990049a051e1 434 Pfam PF03773 Predicted permease 43 431 7.3E-71 T 22-04-2016 IPR005524 Predicted permease DUF318 L21SP4_RS02810 58dc7972c2ae6dbbbf88990049a051e1 434 PANTHER PTHR34184 272 433 2.8E-128 T 22-04-2016 L21SP4_RS02810 58dc7972c2ae6dbbbf88990049a051e1 434 PANTHER PTHR34184 11 213 2.8E-128 T 22-04-2016 L21SP4_RS02810 58dc7972c2ae6dbbbf88990049a051e1 434 PANTHER PTHR34184:SF3 272 433 2.8E-128 T 22-04-2016 L21SP4_RS02810 58dc7972c2ae6dbbbf88990049a051e1 434 PANTHER PTHR34184:SF3 11 213 2.8E-128 T 22-04-2016 L21SP4_RS02880 b59b73f2b4e61be66c2addb4cb6b4e38 95 Pfam PF13683 Integrase core domain 14 79 5.9E-15 T 22-04-2016 IPR001584 Integrase, catalytic core GO:0015074 L21SP4_RS02880 b59b73f2b4e61be66c2addb4cb6b4e38 95 SUPERFAMILY SSF53098 17 89 7.78E-17 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS02880 b59b73f2b4e61be66c2addb4cb6b4e38 95 Gene3D G3DSA:3.30.420.10 19 79 1.0E-7 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS11175 4431f0efcacffc5d1c5a3cb1410dad96 483 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 53 480 4.2E-96 T 22-04-2016 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase L21SP4_RS11175 4431f0efcacffc5d1c5a3cb1410dad96 483 PANTHER PTHR30576 14 483 1.4E-93 T 22-04-2016 L21SP4_RS11175 4431f0efcacffc5d1c5a3cb1410dad96 483 Pfam PF13727 CoA-binding domain 73 237 3.9E-10 T 22-04-2016 L21SP4_RS11175 4431f0efcacffc5d1c5a3cb1410dad96 483 Pfam PF02397 Bacterial sugar transferase 284 477 2.1E-52 T 22-04-2016 IPR003362 Bacterial sugar transferase L21SP4_RS06520 fde131832430febd0206474b418f46c6 386 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 362 386 3.1E-4 T 22-04-2016 IPR013424 PEP-CTERM protein-sorting domain L21SP4_RS06520 fde131832430febd0206474b418f46c6 386 Pfam PF07589 PEP-CTERM motif 362 384 5.4E-4 T 22-04-2016 IPR013424 PEP-CTERM protein-sorting domain L21SP4_RS07345 10cd59c7381ef062234054cebbe4ca58 410 ProSitePatterns PS01219 Ammonium transporters signature. 154 179 - T 22-04-2016 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 L21SP4_RS07345 10cd59c7381ef062234054cebbe4ca58 410 PANTHER PTHR11730:SF6 86 401 1.4E-126 T 22-04-2016 L21SP4_RS07345 10cd59c7381ef062234054cebbe4ca58 410 PANTHER PTHR11730:SF6 1 70 1.4E-126 T 22-04-2016 L21SP4_RS07345 10cd59c7381ef062234054cebbe4ca58 410 PANTHER PTHR11730 86 401 1.4E-126 T 22-04-2016 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 L21SP4_RS07345 10cd59c7381ef062234054cebbe4ca58 410 PANTHER PTHR11730 1 70 1.4E-126 T 22-04-2016 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 L21SP4_RS07345 10cd59c7381ef062234054cebbe4ca58 410 TIGRFAM TIGR00836 amt: ammonium transporter 1 401 4.9E-115 T 22-04-2016 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 L21SP4_RS07345 10cd59c7381ef062234054cebbe4ca58 410 Gene3D G3DSA:1.10.3430.10 1 382 1.6E-106 T 22-04-2016 IPR029020 Ammonium/urea transporter L21SP4_RS07345 10cd59c7381ef062234054cebbe4ca58 410 SUPERFAMILY SSF111352 1 382 2.75E-101 T 22-04-2016 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 L21SP4_RS07345 10cd59c7381ef062234054cebbe4ca58 410 Pfam PF00909 Ammonium Transporter Family 1 401 3.1E-106 T 22-04-2016 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 L21SP4_RS04575 a306c0dfb8bbe5030fce9a77f568c562 345 SUPERFAMILY SSF51735 140 307 2.22E-31 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS04575 a306c0dfb8bbe5030fce9a77f568c562 345 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 22-04-2016 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 L21SP4_RS04575 a306c0dfb8bbe5030fce9a77f568c562 345 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 137 1.7E-31 T 22-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 L21SP4_RS04575 a306c0dfb8bbe5030fce9a77f568c562 345 SMART SM00829 8 339 4.7E-5 T 22-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 L21SP4_RS04575 a306c0dfb8bbe5030fce9a77f568c562 345 PANTHER PTHR11695:SF501 12 345 4.7E-89 T 22-04-2016 L21SP4_RS04575 a306c0dfb8bbe5030fce9a77f568c562 345 Pfam PF00107 Zinc-binding dehydrogenase 177 305 4.9E-23 T 22-04-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 L21SP4_RS04575 a306c0dfb8bbe5030fce9a77f568c562 345 PANTHER PTHR11695 12 345 4.7E-89 T 22-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 L21SP4_RS04575 a306c0dfb8bbe5030fce9a77f568c562 345 SUPERFAMILY SSF50129 1 173 7.39E-47 T 22-04-2016 IPR011032 GroES-like L21SP4_RS04575 a306c0dfb8bbe5030fce9a77f568c562 345 Gene3D G3DSA:3.90.180.10 1 169 3.3E-47 T 22-04-2016 IPR011032 GroES-like L21SP4_RS04575 a306c0dfb8bbe5030fce9a77f568c562 345 Gene3D G3DSA:3.40.50.720 170 288 2.3E-30 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS02020 f21b0ee750db25df602adfe8b187bda5 294 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 269 292 4.1E-5 T 22-04-2016 IPR013424 PEP-CTERM protein-sorting domain L21SP4_RS02020 f21b0ee750db25df602adfe8b187bda5 294 Pfam PF07589 PEP-CTERM motif 269 290 1.5E-5 T 22-04-2016 IPR013424 PEP-CTERM protein-sorting domain L21SP4_RS00765 e61dff10be4613fbfed018c5355afd04 413 SUPERFAMILY SSF51126 34 120 3.4E-22 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor L21SP4_RS00765 e61dff10be4613fbfed018c5355afd04 413 SUPERFAMILY SSF51126 152 355 3.4E-22 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor L21SP4_RS00765 e61dff10be4613fbfed018c5355afd04 413 Pfam PF12708 Pectate lyase superfamily protein 42 110 1.3E-14 T 22-04-2016 IPR024535 Pectate lyase superfamily protein L21SP4_RS00765 e61dff10be4613fbfed018c5355afd04 413 Gene3D G3DSA:2.160.20.10 35 114 1.2E-17 T 22-04-2016 IPR012334 Pectin lyase fold L21SP4_RS01170 34f635344042b5818ed64002993f0835 307 Pfam PF00698 Acyl transferase domain 7 276 3.6E-32 T 22-04-2016 IPR014043 Acyl transferase L21SP4_RS01170 34f635344042b5818ed64002993f0835 307 SUPERFAMILY SSF55048 130 190 8.11E-15 T 22-04-2016 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 L21SP4_RS01170 34f635344042b5818ed64002993f0835 307 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 5 287 2.4E-94 T 22-04-2016 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 L21SP4_RS01170 34f635344042b5818ed64002993f0835 307 Gene3D G3DSA:3.30.70.250 128 193 1.5E-21 T 22-04-2016 L21SP4_RS01170 34f635344042b5818ed64002993f0835 307 SUPERFAMILY SSF52151 4 123 2.35E-75 T 22-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 L21SP4_RS01170 34f635344042b5818ed64002993f0835 307 SUPERFAMILY SSF52151 187 301 2.35E-75 T 22-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 L21SP4_RS01170 34f635344042b5818ed64002993f0835 307 PANTHER PTHR10982 1 305 1.5E-129 T 22-04-2016 L21SP4_RS01170 34f635344042b5818ed64002993f0835 307 Gene3D G3DSA:3.40.366.10 4 123 2.9E-67 T 22-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 L21SP4_RS01170 34f635344042b5818ed64002993f0835 307 Gene3D G3DSA:3.40.366.10 194 299 2.9E-67 T 22-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 L21SP4_RS01170 34f635344042b5818ed64002993f0835 307 PIRSF PIRSF000446 1 305 1.8E-89 T 22-04-2016 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388|UniPathway: UPA00094 L21SP4_RS01170 34f635344042b5818ed64002993f0835 307 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 7 299 1.2E-38 T 22-04-2016 IPR020801 Polyketide synthase, acyl transferase domain L21SP4_RS02645 24dabb1096263172205425c86e10d17d 445 Gene3D G3DSA:3.30.300.30 338 443 6.1E-37 T 22-04-2016 L21SP4_RS02645 24dabb1096263172205425c86e10d17d 445 Pfam PF14535 AMP-binding enzyme C-terminal domain 347 443 1.6E-30 T 22-04-2016 IPR028154 AMP-dependent ligase, C-terminal L21SP4_RS02645 24dabb1096263172205425c86e10d17d 445 Pfam PF00501 AMP-binding enzyme 95 297 7.0E-16 T 22-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 L21SP4_RS02645 24dabb1096263172205425c86e10d17d 445 PIRSF PIRSF006444 10 445 1.6E-201 T 22-04-2016 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716|UniPathway: UPA00930 L21SP4_RS02645 24dabb1096263172205425c86e10d17d 445 PANTHER PTHR24095 74 443 2.0E-120 T 22-04-2016 L21SP4_RS02645 24dabb1096263172205425c86e10d17d 445 SUPERFAMILY SSF56801 33 409 2.75E-61 T 22-04-2016 L21SP4_RS02645 24dabb1096263172205425c86e10d17d 445 Gene3D G3DSA:3.40.50.980 96 255 2.4E-13 T 22-04-2016 L21SP4_RS02645 24dabb1096263172205425c86e10d17d 445 PANTHER PTHR24095:SF175 74 443 2.0E-120 T 22-04-2016 L21SP4_RS09980 99176e9c906a20a1de1b61456a0d4688 300 Gene3D G3DSA:3.90.550.10 5 285 6.9E-26 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases L21SP4_RS09980 99176e9c906a20a1de1b61456a0d4688 300 Pfam PF00483 Nucleotidyl transferase 6 134 1.3E-4 T 22-04-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Reactome: REACT_17015 L21SP4_RS09980 99176e9c906a20a1de1b61456a0d4688 300 SUPERFAMILY SSF53448 5 287 6.08E-25 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases L21SP4_RS04760 4b07d02cf335e5688ab9b7ca485af451 130 Gene3D G3DSA:1.10.10.10 1 129 1.0E-34 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS04760 4b07d02cf335e5688ab9b7ca485af451 130 Pfam PF02082 Transcriptional regulator 1 82 5.7E-25 T 22-04-2016 IPR000944 Transcription regulator Rrf2-type L21SP4_RS04760 4b07d02cf335e5688ab9b7ca485af451 130 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 129 2.9E-36 T 22-04-2016 IPR000944 Transcription regulator Rrf2-type L21SP4_RS04760 4b07d02cf335e5688ab9b7ca485af451 130 PANTHER PTHR33221 2 129 1.8E-40 T 22-04-2016 L21SP4_RS04760 4b07d02cf335e5688ab9b7ca485af451 130 SUPERFAMILY SSF46785 2 129 2.13E-32 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS04760 4b07d02cf335e5688ab9b7ca485af451 130 PANTHER PTHR33221:SF1 2 129 1.8E-40 T 22-04-2016 L21SP4_RS09125 a97fea90ecabafadd3f01bca504ed8f8 62 Gene3D G3DSA:3.30.70.20 1 62 2.6E-19 T 22-04-2016 L21SP4_RS09125 a97fea90ecabafadd3f01bca504ed8f8 62 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 1.9E-9 T 22-04-2016 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 L21SP4_RS09125 a97fea90ecabafadd3f01bca504ed8f8 62 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 1.9E-9 T 22-04-2016 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 L21SP4_RS09125 a97fea90ecabafadd3f01bca504ed8f8 62 PRINTS PR00352 3Fe-4S ferredoxin signature 46 58 1.9E-9 T 22-04-2016 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 L21SP4_RS09125 a97fea90ecabafadd3f01bca504ed8f8 62 SUPERFAMILY SSF54862 2 61 2.29E-15 T 22-04-2016 L21SP4_RS09125 a97fea90ecabafadd3f01bca504ed8f8 62 PANTHER PTHR36923 1 62 7.4E-14 T 22-04-2016 L21SP4_RS09125 a97fea90ecabafadd3f01bca504ed8f8 62 Pfam PF13459 4Fe-4S single cluster domain 4 60 2.7E-14 T 22-04-2016 L21SP4_RS00955 1c18ecf3e24248c9fe6af23834231318 397 Pfam PF13439 Glycosyltransferase Family 4 22 201 1.7E-14 T 22-04-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain L21SP4_RS00955 1c18ecf3e24248c9fe6af23834231318 397 SUPERFAMILY SSF53756 3 387 1.35E-37 T 22-04-2016 L21SP4_RS00955 1c18ecf3e24248c9fe6af23834231318 397 Pfam PF13692 Glycosyl transferases group 1 218 352 4.6E-21 T 22-04-2016 L21SP4_RS00955 1c18ecf3e24248c9fe6af23834231318 397 Gene3D G3DSA:3.40.50.2000 195 366 5.1E-5 T 22-04-2016 L21SP4_RS00955 1c18ecf3e24248c9fe6af23834231318 397 PANTHER PTHR12526 2 139 2.2E-18 T 22-04-2016 L21SP4_RS00955 1c18ecf3e24248c9fe6af23834231318 397 PANTHER PTHR12526 160 387 2.2E-18 T 22-04-2016 L21SP4_RS08050 6d284df82773c2433b6f5db90d26a63d 142 Gene3D G3DSA:2.60.200.20 4 92 9.3E-25 T 22-04-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 L21SP4_RS08050 6d284df82773c2433b6f5db90d26a63d 142 Pfam PF00498 FHA domain 22 86 6.1E-18 T 22-04-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 L21SP4_RS08050 6d284df82773c2433b6f5db90d26a63d 142 SUPERFAMILY SSF49879 3 93 4.78E-25 T 22-04-2016 IPR008984 SMAD/FHA domain GO:0005515 L21SP4_RS08050 6d284df82773c2433b6f5db90d26a63d 142 PANTHER PTHR15715 21 86 5.1E-13 T 22-04-2016 L21SP4_RS08050 6d284df82773c2433b6f5db90d26a63d 142 SMART SM00240 21 71 1.2E-11 T 22-04-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 L21SP4_RS02920 f3524280c7efc7be0ff2fb9f3ca85a0b 188 PANTHER PTHR11922:SF7 1 185 1.9E-92 T 22-04-2016 L21SP4_RS02920 f3524280c7efc7be0ff2fb9f3ca85a0b 188 Gene3D G3DSA:3.40.50.880 1 186 2.7E-65 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like L21SP4_RS02920 f3524280c7efc7be0ff2fb9f3ca85a0b 188 Pfam PF00117 Glutamine amidotransferase class-I 3 185 1.2E-50 T 22-04-2016 IPR017926 Glutamine amidotransferase Reactome: REACT_1698 L21SP4_RS02920 f3524280c7efc7be0ff2fb9f3ca85a0b 188 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 1 187 1.3E-70 T 22-04-2016 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 L21SP4_RS02920 f3524280c7efc7be0ff2fb9f3ca85a0b 188 PRINTS PR00097 Anthranilate synthase component II signature 164 177 9.3E-36 T 22-04-2016 L21SP4_RS02920 f3524280c7efc7be0ff2fb9f3ca85a0b 188 PRINTS PR00097 Anthranilate synthase component II signature 2 16 9.3E-36 T 22-04-2016 L21SP4_RS02920 f3524280c7efc7be0ff2fb9f3ca85a0b 188 PRINTS PR00097 Anthranilate synthase component II signature 74 85 9.3E-36 T 22-04-2016 L21SP4_RS02920 f3524280c7efc7be0ff2fb9f3ca85a0b 188 PRINTS PR00097 Anthranilate synthase component II signature 119 131 9.3E-36 T 22-04-2016 L21SP4_RS02920 f3524280c7efc7be0ff2fb9f3ca85a0b 188 PRINTS PR00097 Anthranilate synthase component II signature 99 107 9.3E-36 T 22-04-2016 L21SP4_RS02920 f3524280c7efc7be0ff2fb9f3ca85a0b 188 PRINTS PR00097 Anthranilate synthase component II signature 47 56 9.3E-36 T 22-04-2016 L21SP4_RS02920 f3524280c7efc7be0ff2fb9f3ca85a0b 188 PRINTS PR00096 Glutamine amidotransferase superfamily signature 164 177 1.5E-13 T 22-04-2016 L21SP4_RS02920 f3524280c7efc7be0ff2fb9f3ca85a0b 188 PRINTS PR00096 Glutamine amidotransferase superfamily signature 47 56 1.5E-13 T 22-04-2016 L21SP4_RS02920 f3524280c7efc7be0ff2fb9f3ca85a0b 188 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 1.5E-13 T 22-04-2016 L21SP4_RS02920 f3524280c7efc7be0ff2fb9f3ca85a0b 188 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 44 58 9.7E-7 T 22-04-2016 L21SP4_RS02920 f3524280c7efc7be0ff2fb9f3ca85a0b 188 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 74 90 9.7E-7 T 22-04-2016 L21SP4_RS02920 f3524280c7efc7be0ff2fb9f3ca85a0b 188 SUPERFAMILY SSF52317 1 186 3.3E-54 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like L21SP4_RS02920 f3524280c7efc7be0ff2fb9f3ca85a0b 188 PANTHER PTHR11922 1 185 1.9E-92 T 22-04-2016 L21SP4_RS04525 1629f419eb9e9a56c40ae3cf0155344f 542 PANTHER PTHR33307:SF5 11 518 4.4E-123 T 22-04-2016 L21SP4_RS04525 1629f419eb9e9a56c40ae3cf0155344f 542 Pfam PF05592 Bacterial alpha-L-rhamnosidase 328 512 4.8E-32 T 22-04-2016 IPR008902 Bacterial alpha-L-rhamnosidase L21SP4_RS04525 1629f419eb9e9a56c40ae3cf0155344f 542 PANTHER PTHR33307 11 518 4.4E-123 T 22-04-2016 L21SP4_RS04525 1629f419eb9e9a56c40ae3cf0155344f 542 Pfam PF08531 Alpha-L-rhamnosidase N-terminal domain 153 315 2.1E-34 T 22-04-2016 IPR013737 Bacterial alpha-L-rhamnosidase N-terminal L21SP4_RS00485 1c7b36718fa571ade2f5f083eff13abb 728 SUPERFAMILY SSF52317 289 546 4.58E-35 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like L21SP4_RS00485 1c7b36718fa571ade2f5f083eff13abb 728 PANTHER PTHR37947 15 728 1.0E-31 T 22-04-2016 L21SP4_RS00485 1c7b36718fa571ade2f5f083eff13abb 728 Gene3D G3DSA:3.40.50.880 279 545 7.2E-41 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like L21SP4_RS00485 1c7b36718fa571ade2f5f083eff13abb 728 Pfam PF07090 Putative glutamine amidotransferase 361 544 9.7E-9 T 22-04-2016 IPR010768 Putative glutamine amidotransferase L21SP4_RS00485 1c7b36718fa571ade2f5f083eff13abb 728 SUPERFAMILY SSF53300 75 169 4.7E-5 T 22-04-2016 IPR002035 von Willebrand factor, type A L21SP4_RS00485 1c7b36718fa571ade2f5f083eff13abb 728 SUPERFAMILY SSF53300 605 684 4.7E-5 T 22-04-2016 IPR002035 von Willebrand factor, type A L21SP4_RS00435 f185cc67beea985f36117edb250207f7 209 SUPERFAMILY SSF158446 11 104 9.68E-16 T 22-04-2016 L21SP4_RS00435 f185cc67beea985f36117edb250207f7 209 TIGRFAM TIGR04258 4helix_suffix: four helix bundle suffix domain 160 208 1.9E-17 T 22-04-2016 IPR026354 Four helix bundle suffix domain L21SP4_RS00435 f185cc67beea985f36117edb250207f7 209 TIGRFAM TIGR02436 TIGR02436: four helix bundle protein 16 86 3.9E-7 T 22-04-2016 IPR012657 23S rRNA-intervening sequence protein L21SP4_RS00435 f185cc67beea985f36117edb250207f7 209 Gene3D G3DSA:1.20.1440.60 16 86 2.2E-4 T 22-04-2016 IPR012657 23S rRNA-intervening sequence protein L21SP4_RS11670 d8bde81f209760f231a030b3acecfea4 262 PANTHER PTHR30093 1 109 1.8E-12 T 22-04-2016 L21SP4_RS11670 d8bde81f209760f231a030b3acecfea4 262 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 7 27 - T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site L21SP4_RS11670 d8bde81f209760f231a030b3acecfea4 262 TIGRFAM TIGR04294 pre_pil_HX9DG: prepilin-type processing-associated H-X9-DG domain 216 229 3.5E-5 T 22-04-2016 IPR027558 Prepilin-type processing-associated H-X9-DG domain L21SP4_RS11670 d8bde81f209760f231a030b3acecfea4 262 SUPERFAMILY SSF54523 9 88 2.12E-11 T 22-04-2016 L21SP4_RS11670 d8bde81f209760f231a030b3acecfea4 262 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 7 21 2.2E-4 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site L21SP4_RS11670 d8bde81f209760f231a030b3acecfea4 262 PRINTS PR00813 Bacterial general secretion pathway protein G signature 8 33 1.7E-5 T 22-04-2016 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 L21SP4_RS11670 d8bde81f209760f231a030b3acecfea4 262 PRINTS PR00813 Bacterial general secretion pathway protein G signature 44 62 1.7E-5 T 22-04-2016 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 L21SP4_RS05100 3cad3282e3b12a8e7dbefa48f59d8796 239 PANTHER PTHR39082 1 235 4.2E-37 T 22-04-2016 L21SP4_RS05100 3cad3282e3b12a8e7dbefa48f59d8796 239 Pfam PF02591 C4-type zinc ribbon domain 198 230 1.0E-10 T 22-04-2016 IPR003743 C4-type zinc ribbon domain L21SP4_RS07290 12413651d7ad20efe8d85ac0547e6d20 158 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 59 96 - T 22-04-2016 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 L21SP4_RS07290 12413651d7ad20efe8d85ac0547e6d20 158 Gene3D G3DSA:3.40.140.10 6 154 1.4E-58 T 22-04-2016 L21SP4_RS07290 12413651d7ad20efe8d85ac0547e6d20 158 SUPERFAMILY SSF53927 7 155 2.17E-53 T 22-04-2016 IPR016193 Cytidine deaminase-like GO:0003824 L21SP4_RS07290 12413651d7ad20efe8d85ac0547e6d20 158 Pfam PF14437 MafB19-like deaminase 13 155 3.4E-39 T 22-04-2016 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 L21SP4_RS07290 12413651d7ad20efe8d85ac0547e6d20 158 PANTHER PTHR11079:SF72 1 155 1.6E-47 T 22-04-2016 L21SP4_RS07290 12413651d7ad20efe8d85ac0547e6d20 158 PANTHER PTHR11079 1 155 1.6E-47 T 22-04-2016 L21SP4_RS07290 12413651d7ad20efe8d85ac0547e6d20 158 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 14 155 45.981 T 22-04-2016 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 L21SP4_RS01040 6c0cd05ea29f4e8184c9e786e71c00b1 69 Pfam PF13560 Helix-turn-helix domain 8 65 1.6E-8 T 22-04-2016 L21SP4_RS01040 6c0cd05ea29f4e8184c9e786e71c00b1 69 SUPERFAMILY SSF47413 6 65 7.88E-12 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 L21SP4_RS01040 6c0cd05ea29f4e8184c9e786e71c00b1 69 TIGRFAM TIGR03070 couple_hipB: transcriptional regulator, y4mF family 7 62 6.2E-22 T 22-04-2016 IPR017507 Transcription regulator, HipB-like L21SP4_RS01040 6c0cd05ea29f4e8184c9e786e71c00b1 69 Gene3D G3DSA:1.10.260.40 5 65 1.0E-11 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 L21SP4_RS01040 6c0cd05ea29f4e8184c9e786e71c00b1 69 SMART SM00530 12 67 0.0025 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 L21SP4_RS02300 16bcd32d4f3fd6a5984f1e5e04e81569 308 PANTHER PTHR11082 1 273 7.0E-50 T 22-04-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 L21SP4_RS02300 16bcd32d4f3fd6a5984f1e5e04e81569 308 Gene3D G3DSA:3.20.20.70 1 227 1.7E-41 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP4_RS02300 16bcd32d4f3fd6a5984f1e5e04e81569 308 Pfam PF01207 Dihydrouridine synthase (Dus) 1 225 3.4E-33 T 22-04-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 L21SP4_RS02300 16bcd32d4f3fd6a5984f1e5e04e81569 308 SUPERFAMILY SSF51395 1 304 6.11E-42 T 22-04-2016 L21SP4_RS02300 16bcd32d4f3fd6a5984f1e5e04e81569 308 PANTHER PTHR11082:SF32 1 273 7.0E-50 T 22-04-2016 L21SP4_RS02300 16bcd32d4f3fd6a5984f1e5e04e81569 308 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 84 102 - T 22-04-2016 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 L21SP4_RS02300 16bcd32d4f3fd6a5984f1e5e04e81569 308 PIRSF PIRSF006621 1 307 4.1E-45 T 22-04-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 L21SP4_RS02850 d8bf6a7e27d5647636387497fb293675 198 TIGRFAM TIGR01939 nqrD: NADH:ubiquinone oxidoreductase, Na(+)-translocating, D subunit 5 191 1.0E-81 T 22-04-2016 IPR011292 Na(+)-translocating NADH-quinone reductase subunit D GO:0016655|GO:0055114 L21SP4_RS02850 d8bf6a7e27d5647636387497fb293675 198 PIRSF PIRSF006102 1 198 2.2E-64 T 22-04-2016 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 L21SP4_RS02850 d8bf6a7e27d5647636387497fb293675 198 PANTHER PTHR30586:SF1 1 191 1.4E-97 T 22-04-2016 IPR011292 Na(+)-translocating NADH-quinone reductase subunit D GO:0016655|GO:0055114 L21SP4_RS02850 d8bf6a7e27d5647636387497fb293675 198 PANTHER PTHR30586 1 191 1.4E-97 T 22-04-2016 L21SP4_RS02850 d8bf6a7e27d5647636387497fb293675 198 Pfam PF02508 Rnf-Nqr subunit, membrane protein 5 185 1.9E-59 T 22-04-2016 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 L21SP4_RS00400 5505ab42ae4a753886b1c88477135943 227 Pfam PF01618 MotA/TolQ/ExbB proton channel family 84 204 2.0E-25 T 22-04-2016 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 L21SP4_RS00400 5505ab42ae4a753886b1c88477135943 227 PANTHER PTHR30625 24 214 1.1E-33 T 22-04-2016 L21SP4_RS09975 2d3720f3f57233dced2f18232098060f 264 SUPERFAMILY SSF56219 1 256 1.01E-69 T 22-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase L21SP4_RS09975 2d3720f3f57233dced2f18232098060f 264 PANTHER PTHR22748:SF7 1 256 2.6E-89 T 22-04-2016 L21SP4_RS09975 2d3720f3f57233dced2f18232098060f 264 Gene3D G3DSA:3.60.10.10 1 256 3.7E-76 T 22-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase L21SP4_RS09975 2d3720f3f57233dced2f18232098060f 264 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 255 1.1E-77 T 22-04-2016 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 L21SP4_RS09975 2d3720f3f57233dced2f18232098060f 264 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 4 248 6.2E-26 T 22-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase L21SP4_RS09975 2d3720f3f57233dced2f18232098060f 264 PANTHER PTHR22748 1 256 2.6E-89 T 22-04-2016 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 L21SP4_RS09975 2d3720f3f57233dced2f18232098060f 264 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 27 36 - T 22-04-2016 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 L21SP4_RS09975 2d3720f3f57233dced2f18232098060f 264 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 254 8.0E-86 T 22-04-2016 L21SP4_RS11495 67680d116583876a5b341eebc6f721f6 320 PRINTS PR01713 Nucleotide sugar epimerase signature 29 45 7.9E-24 T 22-04-2016 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 L21SP4_RS11495 67680d116583876a5b341eebc6f721f6 320 PRINTS PR01713 Nucleotide sugar epimerase signature 216 231 7.9E-24 T 22-04-2016 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 L21SP4_RS11495 67680d116583876a5b341eebc6f721f6 320 PRINTS PR01713 Nucleotide sugar epimerase signature 240 255 7.9E-24 T 22-04-2016 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 L21SP4_RS11495 67680d116583876a5b341eebc6f721f6 320 PRINTS PR01713 Nucleotide sugar epimerase signature 279 296 7.9E-24 T 22-04-2016 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 L21SP4_RS11495 67680d116583876a5b341eebc6f721f6 320 PANTHER PTHR10366 2 316 3.8E-165 T 22-04-2016 L21SP4_RS11495 67680d116583876a5b341eebc6f721f6 320 PANTHER PTHR10366:SF77 2 316 3.8E-165 T 22-04-2016 L21SP4_RS11495 67680d116583876a5b341eebc6f721f6 320 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 307 1.1E-58 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS11495 67680d116583876a5b341eebc6f721f6 320 SUPERFAMILY SSF51735 1 317 4.76E-95 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS11495 67680d116583876a5b341eebc6f721f6 320 Gene3D G3DSA:3.40.50.720 1 183 4.5E-56 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS11495 67680d116583876a5b341eebc6f721f6 320 Gene3D G3DSA:3.90.25.10 184 317 2.4E-30 T 22-04-2016 L21SP4_RS00795 447f2669a0f65128b8c3db06b944c199 842 ProSitePatterns PS00018 EF-hand calcium-binding domain. 802 814 - T 22-04-2016 IPR018247 EF-Hand 1, calcium-binding site L21SP4_RS09900 7c7349d404cd780ff01405faa3753844 125 SUPERFAMILY SSF51230 2 124 1.57E-40 T 22-04-2016 IPR011053 Single hybrid motif L21SP4_RS09900 7c7349d404cd780ff01405faa3753844 125 PANTHER PTHR11715 1 124 3.9E-61 T 22-04-2016 IPR002930 Glycine cleavage system H-protein L21SP4_RS09900 7c7349d404cd780ff01405faa3753844 125 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 46 75 - T 22-04-2016 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site L21SP4_RS09900 7c7349d404cd780ff01405faa3753844 125 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 2 123 1.0E-44 T 22-04-2016 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 L21SP4_RS09900 7c7349d404cd780ff01405faa3753844 125 Pfam PF01597 Glycine cleavage H-protein 6 123 9.6E-43 T 22-04-2016 IPR002930 Glycine cleavage system H-protein L21SP4_RS09900 7c7349d404cd780ff01405faa3753844 125 Gene3D G3DSA:2.40.50.100 5 124 1.7E-46 T 22-04-2016 L21SP4_RS09900 7c7349d404cd780ff01405faa3753844 125 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 3 123 28.024 T 22-04-2016 IPR002930 Glycine cleavage system H-protein L21SP4_RS12040 8ef4859627efa5fe26e68891bae7b6d2 137 Gene3D G3DSA:1.10.10.60 33 109 7.4E-5 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS12040 8ef4859627efa5fe26e68891bae7b6d2 137 SUPERFAMILY SSF46689 24 110 4.48E-6 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS11735 afb7fb8ec794786c8973cdcec9ae3409 240 SUPERFAMILY SSF53098 72 235 3.03E-45 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS11735 afb7fb8ec794786c8973cdcec9ae3409 240 Pfam PF13276 HTH-like domain 3 50 1.1E-6 T 22-04-2016 IPR025948 HTH-like domain L21SP4_RS11735 afb7fb8ec794786c8973cdcec9ae3409 240 Gene3D G3DSA:3.30.420.10 69 224 5.5E-32 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS11735 afb7fb8ec794786c8973cdcec9ae3409 240 Pfam PF00665 Integrase core domain 72 184 4.9E-21 T 22-04-2016 IPR001584 Integrase, catalytic core GO:0015074 L21SP4_RS11735 afb7fb8ec794786c8973cdcec9ae3409 240 PANTHER PTHR32552 23 225 1.8E-25 T 22-04-2016 L21SP4_RS06835 e1185ed42e608e4dcb30718bc47cf935 815 PRINTS PR00418 DNA topoisomerase II family signature 510 527 5.6E-70 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 L21SP4_RS06835 e1185ed42e608e4dcb30718bc47cf935 815 PRINTS PR00418 DNA topoisomerase II family signature 119 133 5.6E-70 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 L21SP4_RS06835 e1185ed42e608e4dcb30718bc47cf935 815 PRINTS PR00418 DNA topoisomerase II family signature 747 763 5.6E-70 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 L21SP4_RS06835 e1185ed42e608e4dcb30718bc47cf935 815 PRINTS PR00418 DNA topoisomerase II family signature 425 439 5.6E-70 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 L21SP4_RS06835 e1185ed42e608e4dcb30718bc47cf935 815 PRINTS PR00418 DNA topoisomerase II family signature 492 508 5.6E-70 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 L21SP4_RS06835 e1185ed42e608e4dcb30718bc47cf935 815 PRINTS PR00418 DNA topoisomerase II family signature 76 89 5.6E-70 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 L21SP4_RS06835 e1185ed42e608e4dcb30718bc47cf935 815 PRINTS PR00418 DNA topoisomerase II family signature 273 286 5.6E-70 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 L21SP4_RS06835 e1185ed42e608e4dcb30718bc47cf935 815 PRINTS PR00418 DNA topoisomerase II family signature 530 542 5.6E-70 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 L21SP4_RS06835 e1185ed42e608e4dcb30718bc47cf935 815 PRINTS PR00418 DNA topoisomerase II family signature 41 56 5.6E-70 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 L21SP4_RS06835 e1185ed42e608e4dcb30718bc47cf935 815 ProSitePatterns PS00177 DNA topoisomerase II signature. 427 435 - T 22-04-2016 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 L21SP4_RS06835 e1185ed42e608e4dcb30718bc47cf935 815 SUPERFAMILY SSF54211 226 396 3.6E-60 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold L21SP4_RS06835 e1185ed42e608e4dcb30718bc47cf935 815 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 9 815 93.957 T 22-04-2016 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 L21SP4_RS06835 e1185ed42e608e4dcb30718bc47cf935 815 Gene3D G3DSA:3.30.565.10 12 223 1.4E-92 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS06835 e1185ed42e608e4dcb30718bc47cf935 815 Pfam PF00204 DNA gyrase B 226 395 2.4E-64 T 22-04-2016 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 L21SP4_RS06835 e1185ed42e608e4dcb30718bc47cf935 815 Gene3D G3DSA:3.30.230.10 225 397 3.9E-75 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup L21SP4_RS06835 e1185ed42e608e4dcb30718bc47cf935 815 Gene3D G3DSA:3.40.50.670 729 797 1.5E-93 T 22-04-2016 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 L21SP4_RS06835 e1185ed42e608e4dcb30718bc47cf935 815 Gene3D G3DSA:3.40.50.670 409 555 1.5E-93 T 22-04-2016 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 L21SP4_RS06835 e1185ed42e608e4dcb30718bc47cf935 815 PRINTS PR01159 DNA gyrase subunit B signature 186 201 1.1E-70 T 22-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 L21SP4_RS06835 e1185ed42e608e4dcb30718bc47cf935 815 PRINTS PR01159 DNA gyrase subunit B signature 201 214 1.1E-70 T 22-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 L21SP4_RS06835 e1185ed42e608e4dcb30718bc47cf935 815 PRINTS PR01159 DNA gyrase subunit B signature 784 800 1.1E-70 T 22-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 L21SP4_RS06835 e1185ed42e608e4dcb30718bc47cf935 815 PRINTS PR01159 DNA gyrase subunit B signature 475 484 1.1E-70 T 22-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 L21SP4_RS06835 e1185ed42e608e4dcb30718bc47cf935 815 PRINTS PR01159 DNA gyrase subunit B signature 365 379 1.1E-70 T 22-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 L21SP4_RS06835 e1185ed42e608e4dcb30718bc47cf935 815 PRINTS PR01159 DNA gyrase subunit B signature 225 247 1.1E-70 T 22-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 L21SP4_RS06835 e1185ed42e608e4dcb30718bc47cf935 815 PRINTS PR01159 DNA gyrase subunit B signature 379 399 1.1E-70 T 22-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 L21SP4_RS06835 e1185ed42e608e4dcb30718bc47cf935 815 PRINTS PR01159 DNA gyrase subunit B signature 768 780 1.1E-70 T 22-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 L21SP4_RS06835 e1185ed42e608e4dcb30718bc47cf935 815 PRINTS PR01159 DNA gyrase subunit B signature 317 333 1.1E-70 T 22-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 L21SP4_RS06835 e1185ed42e608e4dcb30718bc47cf935 815 PRINTS PR01159 DNA gyrase subunit B signature 12 22 1.1E-70 T 22-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 L21SP4_RS06835 e1185ed42e608e4dcb30718bc47cf935 815 SUPERFAMILY SSF55874 12 223 2.68E-72 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS06835 e1185ed42e608e4dcb30718bc47cf935 815 PANTHER PTHR10169 8 558 5.7E-305 T 22-04-2016 L21SP4_RS06835 e1185ed42e608e4dcb30718bc47cf935 815 PANTHER PTHR10169 732 815 5.7E-305 T 22-04-2016 L21SP4_RS06835 e1185ed42e608e4dcb30718bc47cf935 815 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 39 180 3.0E-22 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS06835 e1185ed42e608e4dcb30718bc47cf935 815 Pfam PF01751 Toprim domain 424 536 6.3E-18 T 22-04-2016 IPR006171 Toprim domain L21SP4_RS06835 e1185ed42e608e4dcb30718bc47cf935 815 SMART SM00433 41 808 1.5E-288 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 L21SP4_RS06835 e1185ed42e608e4dcb30718bc47cf935 815 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 12 815 0.0 T 22-04-2016 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 L21SP4_RS06835 e1185ed42e608e4dcb30718bc47cf935 815 SMART SM00387 37 181 1.6E-24 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP4_RS06835 e1185ed42e608e4dcb30718bc47cf935 815 SUPERFAMILY SSF56719 399 565 1.88E-85 T 22-04-2016 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 L21SP4_RS06835 e1185ed42e608e4dcb30718bc47cf935 815 SUPERFAMILY SSF56719 741 807 1.88E-85 T 22-04-2016 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 L21SP4_RS06835 e1185ed42e608e4dcb30718bc47cf935 815 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 743 804 1.2E-28 T 22-04-2016 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 L21SP4_RS08215 896ce771707db93ba858b63546a0bb94 235 PANTHER PTHR33254 86 230 1.4E-28 T 22-04-2016 L21SP4_RS08215 896ce771707db93ba858b63546a0bb94 235 PANTHER PTHR33254:SF5 86 230 1.4E-28 T 22-04-2016 L21SP4_RS08215 896ce771707db93ba858b63546a0bb94 235 SUPERFAMILY SSF89562 23 201 5.49E-32 T 22-04-2016 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein L21SP4_RS08215 896ce771707db93ba858b63546a0bb94 235 Gene3D G3DSA:3.50.30.40 25 201 2.5E-39 T 22-04-2016 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein L21SP4_RS08215 896ce771707db93ba858b63546a0bb94 235 Pfam PF03737 Demethylmenaquinone methyltransferase 26 192 6.4E-30 T 22-04-2016 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein L21SP4_RS11230 af79ce9bb905e6a20be34b951565c26e 261 Pfam PF01522 Polysaccharide deacetylase 19 137 1.9E-6 T 22-04-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 L21SP4_RS11230 af79ce9bb905e6a20be34b951565c26e 261 SUPERFAMILY SSF88713 208 258 3.21E-13 T 22-04-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 L21SP4_RS11230 af79ce9bb905e6a20be34b951565c26e 261 SUPERFAMILY SSF88713 18 151 3.21E-13 T 22-04-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 L21SP4_RS11230 af79ce9bb905e6a20be34b951565c26e 261 Gene3D G3DSA:3.20.20.370 187 259 6.7E-11 T 22-04-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 L21SP4_RS11230 af79ce9bb905e6a20be34b951565c26e 261 Gene3D G3DSA:3.20.20.370 19 137 6.7E-11 T 22-04-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 L21SP4_RS10340 911e89f9c7ec4a6ce88adb56b855f322 175 Gene3D G3DSA:4.10.860.10 132 168 2.9E-6 T 22-04-2016 IPR001943 UVR domain GO:0005515 L21SP4_RS10340 911e89f9c7ec4a6ce88adb56b855f322 175 PIRSF PIRSF015034 1 175 2.2E-45 T 22-04-2016 IPR025542 YacH protein L21SP4_RS10340 911e89f9c7ec4a6ce88adb56b855f322 175 Pfam PF02151 UvrB/uvrC motif 136 168 3.1E-8 T 22-04-2016 IPR001943 UVR domain GO:0005515 L21SP4_RS10340 911e89f9c7ec4a6ce88adb56b855f322 175 PANTHER PTHR38430 2 169 7.1E-40 T 22-04-2016 L21SP4_RS10340 911e89f9c7ec4a6ce88adb56b855f322 175 SUPERFAMILY SSF46600 132 167 6.93E-6 T 22-04-2016 IPR001943 UVR domain GO:0005515 L21SP4_RS04710 d7e7e83ec8d3992bf60f4d82689c8aa2 654 SUPERFAMILY SSF52540 217 352 2.56E-5 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS04710 d7e7e83ec8d3992bf60f4d82689c8aa2 654 Gene3D G3DSA:3.40.50.300 232 428 7.3E-31 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS04710 d7e7e83ec8d3992bf60f4d82689c8aa2 654 Pfam PF09848 Uncharacterized conserved protein (DUF2075) 232 625 7.8E-87 T 22-04-2016 IPR018647 Domain of unknown function DUF2075 L21SP4_RS03185 6a9a41156771fd205f9aff937d9035af 483 PANTHER PTHR30068:SF4 2 468 6.1E-223 T 22-04-2016 L21SP4_RS03185 6a9a41156771fd205f9aff937d9035af 483 Gene3D G3DSA:3.20.20.140 138 464 1.2E-142 T 22-04-2016 L21SP4_RS03185 6a9a41156771fd205f9aff937d9035af 483 Gene3D G3DSA:3.20.20.140 4 44 1.2E-142 T 22-04-2016 L21SP4_RS03185 6a9a41156771fd205f9aff937d9035af 483 Gene3D G3DSA:1.10.2020.10 47 135 1.6E-38 T 22-04-2016 IPR023177 Uronate isomerase, domain 2 GO:0008880 KEGG: 00040+5.3.1.12|MetaCyc: PWY-7247|MetaCyc: PWY-7248|UniPathway: UPA00246 L21SP4_RS03185 6a9a41156771fd205f9aff937d9035af 483 Hamap MF_00675 Uronate isomerase [uxaC]. 2 466 46.27 T 22-04-2016 IPR003766 Uronate isomerase GO:0006064|GO:0008880 KEGG: 00040+5.3.1.12|MetaCyc: PWY-7247|MetaCyc: PWY-7248|UniPathway: UPA00246 L21SP4_RS03185 6a9a41156771fd205f9aff937d9035af 483 Pfam PF02614 Glucuronate isomerase 1 464 9.3E-204 T 22-04-2016 IPR003766 Uronate isomerase GO:0006064|GO:0008880 KEGG: 00040+5.3.1.12|MetaCyc: PWY-7247|MetaCyc: PWY-7248|UniPathway: UPA00246 L21SP4_RS03185 6a9a41156771fd205f9aff937d9035af 483 SUPERFAMILY SSF51556 2 464 1.01E-167 T 22-04-2016 IPR032466 Metal-dependent hydrolase L21SP4_RS03185 6a9a41156771fd205f9aff937d9035af 483 PANTHER PTHR30068 2 468 6.1E-223 T 22-04-2016 L21SP4_RS02120 fa021802f981aa75e0a77bfd7c143a16 82 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 4 45 2.5E-11 T 22-04-2016 IPR007159 SpoVT-AbrB domain GO:0003677 L21SP4_RS02120 fa021802f981aa75e0a77bfd7c143a16 82 Gene3D G3DSA:2.10.260.10 2 46 1.3E-8 T 22-04-2016 L21SP4_RS02120 fa021802f981aa75e0a77bfd7c143a16 82 SMART SM00966 4 50 2.1E-10 T 22-04-2016 IPR007159 SpoVT-AbrB domain GO:0003677 L21SP4_RS02120 fa021802f981aa75e0a77bfd7c143a16 82 Pfam PF15937 prlF antitoxin for toxin YhaV_toxin 4 49 5.0E-8 T 22-04-2016 IPR031848 PrlF antitoxin GO:0001558|GO:0003700|GO:0097351 L21SP4_RS02120 fa021802f981aa75e0a77bfd7c143a16 82 SUPERFAMILY SSF89447 1 43 8.72E-10 T 22-04-2016 L21SP4_RS01775 d0f80d762cfb1f1c3eff747263d57c6e 497 PANTHER PTHR10342:SF199 4 497 3.7E-137 T 22-04-2016 L21SP4_RS01775 d0f80d762cfb1f1c3eff747263d57c6e 497 SUPERFAMILY SSF53649 458 496 1.55E-119 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS01775 d0f80d762cfb1f1c3eff747263d57c6e 497 SUPERFAMILY SSF53649 30 425 1.55E-119 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS01775 d0f80d762cfb1f1c3eff747263d57c6e 497 Gene3D G3DSA:3.30.1120.10 386 496 2.5E-14 T 22-04-2016 L21SP4_RS01775 d0f80d762cfb1f1c3eff747263d57c6e 497 ProSitePatterns PS00149 Sulfatases signature 2. 121 131 - T 22-04-2016 IPR024607 Sulfatase, conserved site L21SP4_RS01775 d0f80d762cfb1f1c3eff747263d57c6e 497 PANTHER PTHR10342 4 497 3.7E-137 T 22-04-2016 L21SP4_RS01775 d0f80d762cfb1f1c3eff747263d57c6e 497 Pfam PF00884 Sulfatase 32 371 3.8E-70 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS01775 d0f80d762cfb1f1c3eff747263d57c6e 497 Gene3D G3DSA:3.40.720.10 29 385 2.0E-102 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS09435 ca924f3e451f0aeedc25a54e9753b242 241 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 218 240 8.0E-5 T 22-04-2016 IPR013424 PEP-CTERM protein-sorting domain L21SP4_RS09435 ca924f3e451f0aeedc25a54e9753b242 241 Pfam PF07589 PEP-CTERM motif 218 238 3.7E-5 T 22-04-2016 IPR013424 PEP-CTERM protein-sorting domain L21SP4_RS03400 cad00fc095b3e079df21a2461c2e12cf 1211 Pfam PF10145 Phage-related minor tail protein 109 295 4.2E-22 T 22-04-2016 IPR010090 Phage tail tape measure protein L21SP4_RS03400 cad00fc095b3e079df21a2461c2e12cf 1211 TIGRFAM TIGR01760 tape_meas_TP901: phage tail tape measure protein, TP901 family, core region 131 405 5.4E-13 T 22-04-2016 IPR010090 Phage tail tape measure protein L21SP4_RS04270 bfce52151c3fdbda71b8e72feb62c51f 632 Gene3D G3DSA:3.40.50.2020 451 520 3.7E-20 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like L21SP4_RS04270 bfce52151c3fdbda71b8e72feb62c51f 632 Gene3D G3DSA:3.40.50.2020 336 399 3.7E-20 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like L21SP4_RS04270 bfce52151c3fdbda71b8e72feb62c51f 632 Gene3D G3DSA:3.60.20.10 8 308 5.1E-48 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal L21SP4_RS04270 bfce52151c3fdbda71b8e72feb62c51f 632 PANTHER PTHR11907:SF0 87 389 1.0E-78 T 22-04-2016 L21SP4_RS04270 bfce52151c3fdbda71b8e72feb62c51f 632 PANTHER PTHR11907:SF0 8 68 1.0E-78 T 22-04-2016 L21SP4_RS04270 bfce52151c3fdbda71b8e72feb62c51f 632 PANTHER PTHR11907:SF0 568 621 1.0E-78 T 22-04-2016 L21SP4_RS04270 bfce52151c3fdbda71b8e72feb62c51f 632 PANTHER PTHR11907:SF0 419 511 1.0E-78 T 22-04-2016 L21SP4_RS04270 bfce52151c3fdbda71b8e72feb62c51f 632 PANTHER PTHR11907 87 389 1.0E-78 T 22-04-2016 L21SP4_RS04270 bfce52151c3fdbda71b8e72feb62c51f 632 PANTHER PTHR11907 8 68 1.0E-78 T 22-04-2016 L21SP4_RS04270 bfce52151c3fdbda71b8e72feb62c51f 632 PANTHER PTHR11907 568 621 1.0E-78 T 22-04-2016 L21SP4_RS04270 bfce52151c3fdbda71b8e72feb62c51f 632 PANTHER PTHR11907 419 511 1.0E-78 T 22-04-2016 L21SP4_RS04270 bfce52151c3fdbda71b8e72feb62c51f 632 SUPERFAMILY SSF56235 90 326 1.12E-40 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal L21SP4_RS04270 bfce52151c3fdbda71b8e72feb62c51f 632 SUPERFAMILY SSF56235 9 60 1.12E-40 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal L21SP4_RS04270 bfce52151c3fdbda71b8e72feb62c51f 632 Pfam PF13537 Glutamine amidotransferase domain 145 279 1.2E-9 T 22-04-2016 IPR017932 Glutamine amidotransferase type 2 domain L21SP4_RS04270 bfce52151c3fdbda71b8e72feb62c51f 632 SUPERFAMILY SSF53271 319 396 4.45E-18 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like L21SP4_RS04270 bfce52151c3fdbda71b8e72feb62c51f 632 SUPERFAMILY SSF53271 425 523 4.45E-18 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like L21SP4_RS03905 d318d0602dca753879495dd48b3f38bc 269 Pfam PF14236 Domain of unknown function (DUF4338) 30 256 9.7E-65 T 22-04-2016 IPR025639 Domain of unknown function DUF4338 L21SP4_RS09790 d318d0602dca753879495dd48b3f38bc 269 Pfam PF14236 Domain of unknown function (DUF4338) 30 256 9.7E-65 T 22-04-2016 IPR025639 Domain of unknown function DUF4338 L21SP4_RS09630 d318d0602dca753879495dd48b3f38bc 269 Pfam PF14236 Domain of unknown function (DUF4338) 30 256 9.7E-65 T 22-04-2016 IPR025639 Domain of unknown function DUF4338 L21SP4_RS06705 d318d0602dca753879495dd48b3f38bc 269 Pfam PF14236 Domain of unknown function (DUF4338) 30 256 9.7E-65 T 22-04-2016 IPR025639 Domain of unknown function DUF4338 L21SP4_RS06430 d318d0602dca753879495dd48b3f38bc 269 Pfam PF14236 Domain of unknown function (DUF4338) 30 256 9.7E-65 T 22-04-2016 IPR025639 Domain of unknown function DUF4338 L21SP4_RS05710 aa7daba44817b571be2c241761c95635 231 PIRSF PIRSF006102 3 227 4.3E-46 T 22-04-2016 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 L21SP4_RS05710 aa7daba44817b571be2c241761c95635 231 Pfam PF02508 Rnf-Nqr subunit, membrane protein 8 222 2.4E-51 T 22-04-2016 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 L21SP4_RS05710 aa7daba44817b571be2c241761c95635 231 PANTHER PTHR30335 5 225 9.6E-82 T 22-04-2016 L21SP4_RS08605 16259ab27f2fa41a2acb1e056d226db3 245 SUPERFAMILY SSF158446 10 102 8.11E-8 T 22-04-2016 L21SP4_RS08605 16259ab27f2fa41a2acb1e056d226db3 245 SUPERFAMILY SSF57783 204 243 1.46E-6 T 22-04-2016 L21SP4_RS08605 16259ab27f2fa41a2acb1e056d226db3 245 Gene3D G3DSA:3.30.65.10 205 243 3.1E-7 T 22-04-2016 L21SP4_RS08605 16259ab27f2fa41a2acb1e056d226db3 245 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 205 243 1.6E-8 T 22-04-2016 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 L21SP4_RS07160 ff033f3820ff1f58f6f88fcdf7bdf008 467 PRINTS PR00415 Aconitase family signature 109 117 4.3E-44 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 L21SP4_RS07160 ff033f3820ff1f58f6f88fcdf7bdf008 467 PRINTS PR00415 Aconitase family signature 345 356 4.3E-44 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 L21SP4_RS07160 ff033f3820ff1f58f6f88fcdf7bdf008 467 PRINTS PR00415 Aconitase family signature 289 303 4.3E-44 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 L21SP4_RS07160 ff033f3820ff1f58f6f88fcdf7bdf008 467 PRINTS PR00415 Aconitase family signature 120 133 4.3E-44 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 L21SP4_RS07160 ff033f3820ff1f58f6f88fcdf7bdf008 467 PRINTS PR00415 Aconitase family signature 210 223 4.3E-44 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 L21SP4_RS07160 ff033f3820ff1f58f6f88fcdf7bdf008 467 PRINTS PR00415 Aconitase family signature 401 414 4.3E-44 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 L21SP4_RS07160 ff033f3820ff1f58f6f88fcdf7bdf008 467 PRINTS PR00415 Aconitase family signature 134 149 4.3E-44 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 L21SP4_RS07160 ff033f3820ff1f58f6f88fcdf7bdf008 467 PRINTS PR00415 Aconitase family signature 83 96 4.3E-44 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 L21SP4_RS07160 ff033f3820ff1f58f6f88fcdf7bdf008 467 PRINTS PR00415 Aconitase family signature 196 209 4.3E-44 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 L21SP4_RS07160 ff033f3820ff1f58f6f88fcdf7bdf008 467 ProSitePatterns PS00450 Aconitase family signature 1. 341 357 - T 22-04-2016 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33|UniPathway: UPA00048 L21SP4_RS07160 ff033f3820ff1f58f6f88fcdf7bdf008 467 PANTHER PTHR11670 1 310 2.2E-249 T 22-04-2016 IPR015937 Aconitase/isopropylmalate dehydratase GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 L21SP4_RS07160 ff033f3820ff1f58f6f88fcdf7bdf008 467 PANTHER PTHR11670 329 467 2.2E-249 T 22-04-2016 IPR015937 Aconitase/isopropylmalate dehydratase GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 L21SP4_RS07160 ff033f3820ff1f58f6f88fcdf7bdf008 467 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 3 467 3.6E-216 T 22-04-2016 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 L21SP4_RS07160 ff033f3820ff1f58f6f88fcdf7bdf008 467 Gene3D G3DSA:3.40.1060.10 169 284 7.1E-35 T 22-04-2016 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 L21SP4_RS07160 ff033f3820ff1f58f6f88fcdf7bdf008 467 Gene3D G3DSA:3.30.499.10 2 166 1.3E-23 T 22-04-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 L21SP4_RS07160 ff033f3820ff1f58f6f88fcdf7bdf008 467 Pfam PF00330 Aconitase family (aconitate hydratase) 8 459 2.1E-148 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 L21SP4_RS07160 ff033f3820ff1f58f6f88fcdf7bdf008 467 ProSitePatterns PS01244 Aconitase family signature 2. 401 414 - T 22-04-2016 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33|UniPathway: UPA00048 L21SP4_RS07160 ff033f3820ff1f58f6f88fcdf7bdf008 467 PANTHER PTHR11670:SF38 1 310 2.2E-249 T 22-04-2016 L21SP4_RS07160 ff033f3820ff1f58f6f88fcdf7bdf008 467 PANTHER PTHR11670:SF38 329 467 2.2E-249 T 22-04-2016 L21SP4_RS07160 ff033f3820ff1f58f6f88fcdf7bdf008 467 Gene3D G3DSA:3.30.499.10 332 467 1.1E-59 T 22-04-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 L21SP4_RS07160 ff033f3820ff1f58f6f88fcdf7bdf008 467 SUPERFAMILY SSF53732 2 467 1.7E-161 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 L21SP4_RS07160 ff033f3820ff1f58f6f88fcdf7bdf008 467 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 2 467 55.907 T 22-04-2016 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 L21SP4_RS02200 68f28917d086f0e1b8ceef8c17c66156 260 PANTHER PTHR30336:SF1 1 247 3.6E-39 T 22-04-2016 L21SP4_RS02200 68f28917d086f0e1b8ceef8c17c66156 260 Gene3D G3DSA:3.40.50.620 77 208 5.3E-15 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP4_RS02200 68f28917d086f0e1b8ceef8c17c66156 260 Pfam PF02698 DUF218 domain 80 241 5.8E-27 T 22-04-2016 IPR003848 Domain of unknown function DUF218 L21SP4_RS02200 68f28917d086f0e1b8ceef8c17c66156 260 PANTHER PTHR30336 1 247 3.6E-39 T 22-04-2016 L21SP4_RS05905 2b717ee8fe454250c2acc659bb982f5f 191 SUPERFAMILY SSF53335 26 161 6.25E-24 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS05905 2b717ee8fe454250c2acc659bb982f5f 191 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 21 156 3.3E-36 T 22-04-2016 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 UniPathway: UPA00989 L21SP4_RS05905 2b717ee8fe454250c2acc659bb982f5f 191 Gene3D G3DSA:3.40.50.150 27 162 6.8E-9 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS05905 2b717ee8fe454250c2acc659bb982f5f 191 PANTHER PTHR23417 11 157 3.8E-38 T 22-04-2016 L21SP4_RS05905 2b717ee8fe454250c2acc659bb982f5f 191 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 1 191 23.798 T 22-04-2016 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 UniPathway: UPA00989 L21SP4_RS05905 2b717ee8fe454250c2acc659bb982f5f 191 PANTHER PTHR23417:SF14 11 157 3.8E-38 T 22-04-2016 L21SP4_RS05905 2b717ee8fe454250c2acc659bb982f5f 191 Pfam PF02390 Putative methyltransferase 24 158 7.0E-40 T 22-04-2016 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 UniPathway: UPA00989 L21SP4_RS04460 611312f8c01c0cab15a4e2b1a9100158 282 SUPERFAMILY SSF53098 46 225 9.86E-9 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS02980 3e6e99347046687fb85617ac84df7e5b 398 SUPERFAMILY SSF103473 6 389 1.7E-31 T 22-04-2016 IPR020846 Major facilitator superfamily domain L21SP4_RS02980 3e6e99347046687fb85617ac84df7e5b 398 Gene3D G3DSA:1.20.1250.20 201 387 7.2E-10 T 22-04-2016 L21SP4_RS02980 3e6e99347046687fb85617ac84df7e5b 398 PANTHER PTHR23514 4 394 1.1E-36 T 22-04-2016 L21SP4_RS02980 3e6e99347046687fb85617ac84df7e5b 398 Gene3D G3DSA:1.20.1250.20 10 182 1.5E-17 T 22-04-2016 L21SP4_RS02980 3e6e99347046687fb85617ac84df7e5b 398 Pfam PF07690 Major Facilitator Superfamily 11 353 1.1E-13 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 L21SP4_RS11725 1084f517fac149340a2e546b93fe72d6 389 Gene3D G3DSA:1.10.238.10 26 86 1.0E-7 T 22-04-2016 IPR011992 EF-hand domain pair L21SP4_RS11725 1084f517fac149340a2e546b93fe72d6 389 Pfam PF10503 Esterase PHB depolymerase 117 254 1.6E-6 T 22-04-2016 IPR010126 Esterase, PHB depolymerase GO:0005576 L21SP4_RS11725 1084f517fac149340a2e546b93fe72d6 389 SUPERFAMILY SSF47473 26 84 3.95E-9 T 22-04-2016 IPR011992 EF-hand domain pair L21SP4_RS11725 1084f517fac149340a2e546b93fe72d6 389 SUPERFAMILY SSF53474 343 367 6.81E-25 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold L21SP4_RS11725 1084f517fac149340a2e546b93fe72d6 389 SUPERFAMILY SSF53474 109 281 6.81E-25 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold L21SP4_RS11725 1084f517fac149340a2e546b93fe72d6 389 Gene3D G3DSA:3.40.50.1820 106 388 3.5E-36 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold L21SP4_RS11725 1084f517fac149340a2e546b93fe72d6 389 ProSitePatterns PS00018 EF-hand calcium-binding domain. 62 74 - T 22-04-2016 IPR018247 EF-Hand 1, calcium-binding site L21SP4_RS11725 1084f517fac149340a2e546b93fe72d6 389 PANTHER PTHR10655:SF33 105 280 2.4E-35 T 22-04-2016 L21SP4_RS11725 1084f517fac149340a2e546b93fe72d6 389 PANTHER PTHR10655 105 280 2.4E-35 T 22-04-2016 L21SP4_RS01340 8a7afc54308c7f9ba485705ffaca960a 136 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 9 29 - T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site L21SP4_RS01340 8a7afc54308c7f9ba485705ffaca960a 136 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 9 29 5.0E-4 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site L21SP4_RS01340 8a7afc54308c7f9ba485705ffaca960a 136 SUPERFAMILY SSF54523 11 108 6.36E-5 T 22-04-2016 L21SP4_RS01340 8a7afc54308c7f9ba485705ffaca960a 136 Pfam PF13544 Type IV pilin N-term methylation site GFxxxE 6 29 9.8E-7 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site L21SP4_RS08500 fa4345e4a668043dcc4b69a402db8c40 566 PANTHER PTHR10657 1 171 1.1E-17 T 22-04-2016 L21SP4_RS08500 fa4345e4a668043dcc4b69a402db8c40 566 PANTHER PTHR10657 206 259 1.1E-17 T 22-04-2016 L21SP4_RS08500 fa4345e4a668043dcc4b69a402db8c40 566 SUPERFAMILY SSF109998 53 172 3.02E-15 T 22-04-2016 IPR027304 Trigger factor/SurA domain L21SP4_RS08500 fa4345e4a668043dcc4b69a402db8c40 566 SUPERFAMILY SSF109998 206 256 3.02E-15 T 22-04-2016 IPR027304 Trigger factor/SurA domain L21SP4_RS08500 fa4345e4a668043dcc4b69a402db8c40 566 Pfam PF13624 SurA N-terminal domain 2 168 1.2E-18 T 22-04-2016 L21SP4_RS08500 fa4345e4a668043dcc4b69a402db8c40 566 PANTHER PTHR10657:SF11 1 171 1.1E-17 T 22-04-2016 L21SP4_RS08500 fa4345e4a668043dcc4b69a402db8c40 566 PANTHER PTHR10657:SF11 206 259 1.1E-17 T 22-04-2016 L21SP4_RS10180 ad04061a5aeb93105a61e826d8f49115 267 Pfam PF01797 Transposase IS200 like 12 123 1.2E-13 T 22-04-2016 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 L21SP4_RS10180 ad04061a5aeb93105a61e826d8f49115 267 SMART SM01321 9 125 4.8E-28 T 22-04-2016 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 L21SP4_RS10180 ad04061a5aeb93105a61e826d8f49115 267 PANTHER PTHR34322:SF1 3 231 1.7E-48 T 22-04-2016 L21SP4_RS10180 ad04061a5aeb93105a61e826d8f49115 267 PANTHER PTHR34322 3 231 1.7E-48 T 22-04-2016 L21SP4_RS10180 ad04061a5aeb93105a61e826d8f49115 267 SUPERFAMILY SSF143422 1 130 1.57E-22 T 22-04-2016 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 L21SP4_RS10180 ad04061a5aeb93105a61e826d8f49115 267 Gene3D G3DSA:3.30.70.1290 7 128 5.6E-13 T 22-04-2016 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 L21SP4_RS11820 ad04061a5aeb93105a61e826d8f49115 267 Pfam PF01797 Transposase IS200 like 12 123 1.2E-13 T 22-04-2016 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 L21SP4_RS11820 ad04061a5aeb93105a61e826d8f49115 267 SMART SM01321 9 125 4.8E-28 T 22-04-2016 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 L21SP4_RS11820 ad04061a5aeb93105a61e826d8f49115 267 PANTHER PTHR34322:SF1 3 231 1.7E-48 T 22-04-2016 L21SP4_RS11820 ad04061a5aeb93105a61e826d8f49115 267 PANTHER PTHR34322 3 231 1.7E-48 T 22-04-2016 L21SP4_RS11820 ad04061a5aeb93105a61e826d8f49115 267 SUPERFAMILY SSF143422 1 130 1.57E-22 T 22-04-2016 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 L21SP4_RS11820 ad04061a5aeb93105a61e826d8f49115 267 Gene3D G3DSA:3.30.70.1290 7 128 5.6E-13 T 22-04-2016 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 L21SP4_RS06095 23a3e826b2a78d3f3d689557637b96aa 114 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 1 107 1.7E-22 T 22-04-2016 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 L21SP4_RS06095 23a3e826b2a78d3f3d689557637b96aa 114 PANTHER PTHR33495 1 114 4.0E-27 T 22-04-2016 L21SP4_RS06095 23a3e826b2a78d3f3d689557637b96aa 114 SUPERFAMILY SSF52091 1 110 1.7E-27 T 22-04-2016 IPR002645 STAS domain L21SP4_RS06095 23a3e826b2a78d3f3d689557637b96aa 114 Pfam PF01740 STAS domain 4 108 5.5E-19 T 22-04-2016 IPR002645 STAS domain L21SP4_RS06095 23a3e826b2a78d3f3d689557637b96aa 114 Gene3D G3DSA:3.30.750.24 1 112 3.6E-32 T 22-04-2016 IPR002645 STAS domain L21SP4_RS06080 c0ff6ff7358b5d063013bcf12339d6a0 317 SUPERFAMILY SSF52151 15 207 1.62E-54 T 22-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 L21SP4_RS06080 c0ff6ff7358b5d063013bcf12339d6a0 317 Pfam PF01734 Patatin-like phospholipase 20 180 6.5E-18 T 22-04-2016 IPR002641 Patatin/Phospholipase A2-related GO:0006629 L21SP4_RS06080 c0ff6ff7358b5d063013bcf12339d6a0 317 PANTHER PTHR14226:SF24 5 317 1.1E-86 T 22-04-2016 L21SP4_RS06080 c0ff6ff7358b5d063013bcf12339d6a0 317 PANTHER PTHR14226 5 317 1.1E-86 T 22-04-2016 L21SP4_RS06080 c0ff6ff7358b5d063013bcf12339d6a0 317 Gene3D G3DSA:3.40.1090.10 47 183 3.2E-8 T 22-04-2016 L21SP4_RS02625 9e128d2d66a05b5d288d09eabfa4cf8f 245 Pfam PF03629 Carbohydrate esterase, sialic acid-specific acetylesterase 114 229 1.0E-9 T 22-04-2016 IPR005181 Sialate O-acetylesterase domain L21SP4_RS02625 9e128d2d66a05b5d288d09eabfa4cf8f 245 SUPERFAMILY SSF52266 27 235 1.68E-36 T 22-04-2016 IPR013830 SGNH hydrolase-type esterase domain L21SP4_RS02625 9e128d2d66a05b5d288d09eabfa4cf8f 245 Gene3D G3DSA:3.40.50.1110 44 228 9.1E-4 T 22-04-2016 IPR013830 SGNH hydrolase-type esterase domain L21SP4_RS08040 c69e5deebf2f2b1761ed8b7f3f0714f2 211 PANTHER PTHR37833 3 204 6.3E-16 T 22-04-2016 L21SP4_RS08040 c69e5deebf2f2b1761ed8b7f3f0714f2 211 Pfam PF07610 Protein of unknown function (DUF1573) 37 80 2.3E-13 T 22-04-2016 IPR011467 Protein of unknown function DUF1573 L21SP4_RS08040 c69e5deebf2f2b1761ed8b7f3f0714f2 211 Gene3D G3DSA:2.60.40.360 10 111 3.3E-24 T 22-04-2016 IPR008962 PapD-like L21SP4_RS08040 c69e5deebf2f2b1761ed8b7f3f0714f2 211 PANTHER PTHR37833:SF1 3 204 6.3E-16 T 22-04-2016 L21SP4_RS09505 0715e4a8fa815741e4179194dcbee5f8 184 Pfam PF02563 Polysaccharide biosynthesis/export protein 26 100 1.5E-11 T 22-04-2016 IPR003715 Polysaccharide export protein GO:0015159|GO:0015774|GO:0016020 L21SP4_RS09505 0715e4a8fa815741e4179194dcbee5f8 184 Gene3D G3DSA:3.30.1950.10 48 99 7.1E-8 T 22-04-2016 L21SP4_RS09505 0715e4a8fa815741e4179194dcbee5f8 184 PANTHER PTHR33619 28 179 1.2E-22 T 22-04-2016 L21SP4_RS09505 0715e4a8fa815741e4179194dcbee5f8 184 SUPERFAMILY SSF142984 104 159 1.24E-5 T 22-04-2016 L21SP4_RS09505 0715e4a8fa815741e4179194dcbee5f8 184 Pfam PF10531 SLBB domain 106 152 2.0E-13 T 22-04-2016 IPR019554 Soluble ligand binding domain L21SP4_RS09505 0715e4a8fa815741e4179194dcbee5f8 184 Gene3D G3DSA:3.10.560.10 100 179 2.3E-18 T 22-04-2016 L21SP4_RS07875 baba2d2feb4e85dcea7de164a26e2a30 78 SUPERFAMILY SSF50037 5 74 8.01E-19 T 22-04-2016 IPR008988 Transcriptional repressor, C-terminal L21SP4_RS07875 baba2d2feb4e85dcea7de164a26e2a30 78 Pfam PF04023 FeoA domain 1 73 4.9E-17 T 22-04-2016 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 L21SP4_RS07875 baba2d2feb4e85dcea7de164a26e2a30 78 PANTHER PTHR33238 1 78 6.2E-22 T 22-04-2016 L21SP4_RS07875 baba2d2feb4e85dcea7de164a26e2a30 78 SMART SM00899 1 74 1.5E-21 T 22-04-2016 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 L21SP4_RS04920 b27863a766cb36d85ae148dbab5490a5 378 PANTHER PTHR30474:SF1 13 377 7.5E-132 T 22-04-2016 IPR011923 Rod shape-determining protein RodA GO:0008360|GO:0016021 L21SP4_RS04920 b27863a766cb36d85ae148dbab5490a5 378 PANTHER PTHR30474 13 377 7.5E-132 T 22-04-2016 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 L21SP4_RS04920 b27863a766cb36d85ae148dbab5490a5 378 Pfam PF01098 Cell cycle protein 20 374 2.7E-92 T 22-04-2016 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 L21SP4_RS04920 b27863a766cb36d85ae148dbab5490a5 378 TIGRFAM TIGR02210 rodA_shape: rod shape-determining protein RodA 14 374 9.1E-117 T 22-04-2016 IPR011923 Rod shape-determining protein RodA GO:0008360|GO:0016021 L21SP4_RS02720 6ac415b23cfac3ba2bf1cb019895892a 191 SUPERFAMILY SSF53335 17 176 3.1E-31 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS02720 6ac415b23cfac3ba2bf1cb019895892a 191 PANTHER PTHR10108 8 139 2.5E-20 T 22-04-2016 L21SP4_RS02720 6ac415b23cfac3ba2bf1cb019895892a 191 Pfam PF08241 Methyltransferase domain 37 139 1.0E-15 T 22-04-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 L21SP4_RS02720 6ac415b23cfac3ba2bf1cb019895892a 191 Gene3D G3DSA:3.40.50.150 19 169 7.4E-29 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS04185 2dcf1e223c7c862d9641f549e337fd99 275 PANTHER PTHR37211:SF1 12 275 2.6E-29 T 22-04-2016 L21SP4_RS04185 2dcf1e223c7c862d9641f549e337fd99 275 Gene3D G3DSA:3.40.50.150 208 239 7.9E-14 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS04185 2dcf1e223c7c862d9641f549e337fd99 275 Gene3D G3DSA:3.40.50.150 38 153 7.9E-14 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS04185 2dcf1e223c7c862d9641f549e337fd99 275 SUPERFAMILY SSF53335 31 239 5.07E-18 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS04185 2dcf1e223c7c862d9641f549e337fd99 275 PANTHER PTHR37211 12 275 2.6E-29 T 22-04-2016 L21SP4_RS09465 3c83d6d2719398cb923c277ca9ab5bf4 320 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 296 318 7.9E-5 T 22-04-2016 IPR013424 PEP-CTERM protein-sorting domain L21SP4_RS01045 99ca4a2610794f55f8828f1017e017f0 413 PANTHER PTHR37419:SF3 4 337 9.2E-63 T 22-04-2016 L21SP4_RS01045 99ca4a2610794f55f8828f1017e017f0 413 Pfam PF07805 HipA-like N-terminal domain 147 226 3.8E-19 T 22-04-2016 IPR012894 HipA, N-terminal subdomain 2 L21SP4_RS01045 99ca4a2610794f55f8828f1017e017f0 413 Pfam PF13657 HipA N-terminal domain 4 102 1.8E-25 T 22-04-2016 IPR017508 HipA, N-terminal subdomain 1 L21SP4_RS01045 99ca4a2610794f55f8828f1017e017f0 413 Pfam PF07804 HipA-like C-terminal domain 236 379 2.3E-37 T 22-04-2016 IPR012893 HipA-like, C-terminal L21SP4_RS01045 99ca4a2610794f55f8828f1017e017f0 413 TIGRFAM TIGR03071 couple_hipA: HipA N-terminal domain 4 102 4.5E-30 T 22-04-2016 IPR017508 HipA, N-terminal subdomain 1 L21SP4_RS01045 99ca4a2610794f55f8828f1017e017f0 413 PANTHER PTHR37419 4 337 9.2E-63 T 22-04-2016 L21SP4_RS03540 fe51f58d66cd3c86a487dc4f9eea511e 138 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 15 37 5.4E-7 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site L21SP4_RS03540 fe51f58d66cd3c86a487dc4f9eea511e 138 PRINTS PR00813 Bacterial general secretion pathway protein G signature 16 41 7.6E-15 T 22-04-2016 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 L21SP4_RS03540 fe51f58d66cd3c86a487dc4f9eea511e 138 PRINTS PR00813 Bacterial general secretion pathway protein G signature 52 70 7.6E-15 T 22-04-2016 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 L21SP4_RS03540 fe51f58d66cd3c86a487dc4f9eea511e 138 Pfam PF13633 Prokaryotic N-terminal methylation site 15 38 5.1E-7 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site L21SP4_RS03540 fe51f58d66cd3c86a487dc4f9eea511e 138 SUPERFAMILY SSF54523 42 130 6.28E-24 T 22-04-2016 L21SP4_RS03540 fe51f58d66cd3c86a487dc4f9eea511e 138 Pfam PF08334 Type II secretion system (T2SS), protein G 40 131 1.5E-27 T 22-04-2016 IPR013545 Type II secretion system protein G L21SP4_RS03540 fe51f58d66cd3c86a487dc4f9eea511e 138 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 15 35 - T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site L21SP4_RS03540 fe51f58d66cd3c86a487dc4f9eea511e 138 PANTHER PTHR30093:SF9 1 132 1.9E-35 T 22-04-2016 L21SP4_RS03540 fe51f58d66cd3c86a487dc4f9eea511e 138 Gene3D G3DSA:3.30.700.10 17 94 3.0E-12 T 22-04-2016 L21SP4_RS03540 fe51f58d66cd3c86a487dc4f9eea511e 138 PANTHER PTHR30093 1 132 1.9E-35 T 22-04-2016 L21SP4_RS03540 fe51f58d66cd3c86a487dc4f9eea511e 138 TIGRFAM TIGR01710 typeII_sec_gspG: type II secretion system protein G 16 132 3.9E-35 T 22-04-2016 IPR010054 General secretion pathway protein G GO:0008565|GO:0015627|GO:0015628 L21SP4_RS11775 f0d52a14c34a54fb796d74b388df6474 68 Pfam PF13711 Domain of unknown function (DUF4160) 8 47 1.4E-5 T 22-04-2016 IPR025427 Protein of unknown function DUF4160 L21SP4_RS01155 d1ce9413c6ee0d93bcce9ab0872618eb 61 PANTHER PTHR21026 1 57 1.2E-14 T 22-04-2016 L21SP4_RS01155 d1ce9413c6ee0d93bcce9ab0872618eb 61 Pfam PF01783 Ribosomal L32p protein family 2 56 5.3E-19 T 22-04-2016 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 L21SP4_RS01155 d1ce9413c6ee0d93bcce9ab0872618eb 61 SUPERFAMILY SSF57829 1 55 9.16E-19 T 22-04-2016 IPR011332 Zinc-binding ribosomal protein GO:0006412 L21SP4_RS01155 d1ce9413c6ee0d93bcce9ab0872618eb 61 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 55 17.169 T 22-04-2016 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 L21SP4_RS01155 d1ce9413c6ee0d93bcce9ab0872618eb 61 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 55 1.9E-20 T 22-04-2016 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 L21SP4_RS03050 5b412972a5f2f434e3e831ed925d4879 109 SUPERFAMILY SSF52091 5 106 1.14E-19 T 22-04-2016 IPR002645 STAS domain L21SP4_RS03050 5b412972a5f2f434e3e831ed925d4879 109 Pfam PF13466 STAS domain 17 92 6.4E-12 T 22-04-2016 IPR002645 STAS domain L21SP4_RS03050 5b412972a5f2f434e3e831ed925d4879 109 Gene3D G3DSA:3.30.750.24 14 107 1.5E-23 T 22-04-2016 IPR002645 STAS domain L21SP4_RS03050 5b412972a5f2f434e3e831ed925d4879 109 PANTHER PTHR33495 16 106 1.3E-18 T 22-04-2016 L21SP4_RS03050 5b412972a5f2f434e3e831ed925d4879 109 PANTHER PTHR33495:SF3 16 106 1.3E-18 T 22-04-2016 L21SP4_RS03050 5b412972a5f2f434e3e831ed925d4879 109 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 14 103 1.3E-18 T 22-04-2016 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 L21SP4_RS09635 8f5492601fc740cc5c4bb1ca9a3fb675 494 PANTHER PTHR33678 17 494 2.9E-127 T 22-04-2016 L21SP4_RS09635 8f5492601fc740cc5c4bb1ca9a3fb675 494 Pfam PF13005 zinc-finger binding domain of transposase IS66 116 159 2.1E-7 T 22-04-2016 IPR024474 Zinc-finger binding domain of transposase IS66 L21SP4_RS09635 8f5492601fc740cc5c4bb1ca9a3fb675 494 PANTHER PTHR33678:SF2 17 494 2.9E-127 T 22-04-2016 L21SP4_RS09635 8f5492601fc740cc5c4bb1ca9a3fb675 494 Pfam PF03050 Transposase IS66 family 175 456 6.9E-60 T 22-04-2016 IPR004291 Transposase, IS66 L21SP4_RS00170 fbfc30bca882a0c1cbc9bd38b867f49a 297 Pfam PF00892 EamA-like transporter family 155 289 6.8E-27 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 L21SP4_RS00170 fbfc30bca882a0c1cbc9bd38b867f49a 297 Pfam PF00892 EamA-like transporter family 5 143 3.1E-16 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 L21SP4_RS00170 fbfc30bca882a0c1cbc9bd38b867f49a 297 SUPERFAMILY SSF103481 43 147 9.42E-16 T 22-04-2016 L21SP4_RS00170 fbfc30bca882a0c1cbc9bd38b867f49a 297 SUPERFAMILY SSF103481 190 294 1.29E-18 T 22-04-2016 L21SP4_RS00170 fbfc30bca882a0c1cbc9bd38b867f49a 297 PANTHER PTHR12715 5 296 1.0E-47 T 22-04-2016 L21SP4_RS03620 197c58b21242ab5cd095a75c688772ff 177 Pfam PF04138 GtrA-like protein 35 175 6.2E-10 T 22-04-2016 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 L21SP4_RS03095 3a56840a6d4814d79821ac03db7e46a9 393 Pfam PF13692 Glycosyl transferases group 1 220 355 2.2E-30 T 22-04-2016 L21SP4_RS03095 3a56840a6d4814d79821ac03db7e46a9 393 Pfam PF13439 Glycosyltransferase Family 4 17 206 8.5E-8 T 22-04-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain L21SP4_RS03095 3a56840a6d4814d79821ac03db7e46a9 393 PANTHER PTHR12526 1 393 1.2E-30 T 22-04-2016 L21SP4_RS03095 3a56840a6d4814d79821ac03db7e46a9 393 Gene3D G3DSA:3.40.50.2000 240 367 1.3E-4 T 22-04-2016 L21SP4_RS03095 3a56840a6d4814d79821ac03db7e46a9 393 PANTHER PTHR12526:SF141 1 393 1.2E-30 T 22-04-2016 L21SP4_RS03095 3a56840a6d4814d79821ac03db7e46a9 393 SUPERFAMILY SSF53756 1 391 5.23E-40 T 22-04-2016 L21SP4_RS05210 e58a277427d6b1bbd397cb8fcd885c54 1070 SUPERFAMILY SSF48452 834 901 2.89E-12 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS05210 e58a277427d6b1bbd397cb8fcd885c54 1070 SUPERFAMILY SSF48452 967 1014 2.89E-12 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS05210 e58a277427d6b1bbd397cb8fcd885c54 1070 Pfam PF14559 Tetratricopeptide repeat 840 902 1.1E-5 T 22-04-2016 L21SP4_RS05210 e58a277427d6b1bbd397cb8fcd885c54 1070 Pfam PF11028 Protein of unknown function (DUF2723) 48 228 5.4E-33 T 22-04-2016 IPR021280 Protein of unknown function DUF2723 L21SP4_RS05210 e58a277427d6b1bbd397cb8fcd885c54 1070 Gene3D G3DSA:1.25.40.10 828 1014 5.4E-18 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS05210 e58a277427d6b1bbd397cb8fcd885c54 1070 Pfam PF13432 Tetratricopeptide repeat 967 1026 2.2E-5 T 22-04-2016 L21SP4_RS05210 e58a277427d6b1bbd397cb8fcd885c54 1070 PANTHER PTHR16214 1 247 8.6E-49 T 22-04-2016 L21SP4_RS05210 e58a277427d6b1bbd397cb8fcd885c54 1070 PANTHER PTHR16214 350 546 8.6E-49 T 22-04-2016 L21SP4_RS00935 fd906e0a87c44d0b9a1c36376b123df0 340 Pfam PF13641 Glycosyltransferase like family 2 12 219 2.9E-20 T 22-04-2016 L21SP4_RS00935 fd906e0a87c44d0b9a1c36376b123df0 340 Gene3D G3DSA:3.90.550.10 13 231 4.6E-36 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases L21SP4_RS00935 fd906e0a87c44d0b9a1c36376b123df0 340 PANTHER PTHR22916 12 219 6.7E-36 T 22-04-2016 L21SP4_RS00935 fd906e0a87c44d0b9a1c36376b123df0 340 SUPERFAMILY SSF53448 11 229 6.28E-42 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases L21SP4_RS01565 43a9017c47c512c32495f726d5728d20 377 SUPERFAMILY SSF51726 135 351 1.15E-14 T 22-04-2016 L21SP4_RS01565 43a9017c47c512c32495f726d5728d20 377 SUPERFAMILY SSF51726 4 102 1.15E-14 T 22-04-2016 L21SP4_RS01565 43a9017c47c512c32495f726d5728d20 377 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 213 348 4.9E-7 T 22-04-2016 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 L21SP4_RS01565 43a9017c47c512c32495f726d5728d20 377 Gene3D G3DSA:3.20.20.210 211 351 1.6E-11 T 22-04-2016 L21SP4_RS09880 9ed92d67f1ca15783f08891d55956b1b 302 PANTHER PTHR10584:SF188 2 290 4.9E-45 T 22-04-2016 L21SP4_RS09880 9ed92d67f1ca15783f08891d55956b1b 302 PANTHER PTHR10584 2 290 4.9E-45 T 22-04-2016 L21SP4_RS09880 9ed92d67f1ca15783f08891d55956b1b 302 Pfam PF00294 pfkB family carbohydrate kinase 25 291 3.9E-32 T 22-04-2016 IPR011611 Carbohydrate kinase PfkB L21SP4_RS09880 9ed92d67f1ca15783f08891d55956b1b 302 SUPERFAMILY SSF53613 12 291 8.48E-49 T 22-04-2016 IPR029056 Ribokinase-like L21SP4_RS09880 9ed92d67f1ca15783f08891d55956b1b 302 Gene3D G3DSA:3.40.1190.20 10 290 2.9E-51 T 22-04-2016 IPR029056 Ribokinase-like L21SP4_RS08575 e4125540bf8746937092205dc1cd4f00 284 PANTHER PTHR30371 15 273 8.4E-74 T 22-04-2016 L21SP4_RS08575 e4125540bf8746937092205dc1cd4f00 284 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 16 255 17.563 T 22-04-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 L21SP4_RS08575 e4125540bf8746937092205dc1cd4f00 284 Pfam PF00902 Sec-independent protein translocase protein (TatC) 23 235 3.3E-59 T 22-04-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 L21SP4_RS08575 e4125540bf8746937092205dc1cd4f00 284 PANTHER PTHR30371:SF0 15 273 8.4E-74 T 22-04-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 L21SP4_RS08575 e4125540bf8746937092205dc1cd4f00 284 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 22 240 1.8E-53 T 22-04-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 L21SP4_RS08575 e4125540bf8746937092205dc1cd4f00 284 ProSitePatterns PS01218 TatC family signature. 168 187 - T 22-04-2016 IPR019820 Sec-independent periplasmic protein translocase, conserved site L21SP4_RS08575 e4125540bf8746937092205dc1cd4f00 284 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 116 142 2.9E-31 T 22-04-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 L21SP4_RS08575 e4125540bf8746937092205dc1cd4f00 284 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 168 196 2.9E-31 T 22-04-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 L21SP4_RS08575 e4125540bf8746937092205dc1cd4f00 284 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 20 47 2.9E-31 T 22-04-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 L21SP4_RS08575 e4125540bf8746937092205dc1cd4f00 284 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 98 116 2.9E-31 T 22-04-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 L21SP4_RS07385 53c25d1e1e624d2f0264968ec446c72f 225 Pfam PF07758 Protein of unknown function (DUF1614) 50 224 3.9E-49 T 22-04-2016 IPR011672 Protein of unknown function DUF1614 L21SP4_RS05380 cc925db3b6a0f27eef320797f1328410 136 Gene3D G3DSA:3.30.1130.10 16 134 6.9E-46 T 22-04-2016 L21SP4_RS05380 cc925db3b6a0f27eef320797f1328410 136 Hamap MF_00818 NADPH-dependent 7-cyano-7-deazaguanine reductase [queF]. 1 136 46.797 T 22-04-2016 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700|UniPathway: UPA00392 L21SP4_RS05380 cc925db3b6a0f27eef320797f1328410 136 TIGRFAM TIGR03139 QueF-II: 7-cyano-7-deazaguanine reductase 25 134 1.7E-47 T 22-04-2016 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700|UniPathway: UPA00392 L21SP4_RS05380 cc925db3b6a0f27eef320797f1328410 136 Pfam PF14489 QueF-like protein 59 134 3.2E-28 T 22-04-2016 IPR029500 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF GO:0008616|GO:0033739 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700|UniPathway: UPA00392 L21SP4_RS05380 cc925db3b6a0f27eef320797f1328410 136 PANTHER PTHR34354:SF1 16 136 5.5E-45 T 22-04-2016 L21SP4_RS05380 cc925db3b6a0f27eef320797f1328410 136 PIRSF PIRSF027377 4 136 4.6E-50 T 22-04-2016 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700|UniPathway: UPA00392 L21SP4_RS05380 cc925db3b6a0f27eef320797f1328410 136 SUPERFAMILY SSF55620 17 130 4.52E-24 T 22-04-2016 L21SP4_RS05380 cc925db3b6a0f27eef320797f1328410 136 PANTHER PTHR34354 16 136 5.5E-45 T 22-04-2016 L21SP4_RS09200 f47661e23923b999ce50fc4130cf5cd3 258 SUPERFAMILY SSF51735 1 230 1.22E-52 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS09200 f47661e23923b999ce50fc4130cf5cd3 258 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 22-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 L21SP4_RS09200 f47661e23923b999ce50fc4130cf5cd3 258 Pfam PF00106 short chain dehydrogenase 7 192 2.9E-41 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS09200 f47661e23923b999ce50fc4130cf5cd3 258 Gene3D G3DSA:3.40.50.720 1 200 2.2E-51 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS09200 f47661e23923b999ce50fc4130cf5cd3 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 3.2E-19 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS09200 f47661e23923b999ce50fc4130cf5cd3 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 3.2E-19 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS09200 f47661e23923b999ce50fc4130cf5cd3 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 3.2E-19 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS09200 f47661e23923b999ce50fc4130cf5cd3 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 3.2E-19 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS09200 f47661e23923b999ce50fc4130cf5cd3 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 3.2E-19 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS09200 f47661e23923b999ce50fc4130cf5cd3 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 3.3E-8 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS09200 f47661e23923b999ce50fc4130cf5cd3 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 3.3E-8 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS09200 f47661e23923b999ce50fc4130cf5cd3 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 3.3E-8 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS09200 f47661e23923b999ce50fc4130cf5cd3 258 PANTHER PTHR24322 10 136 7.0E-35 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS09200 f47661e23923b999ce50fc4130cf5cd3 258 PANTHER PTHR24322 152 182 7.0E-35 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP4_RS05630 52aaba04ea7f8a3644d277efd64223f2 390 SUPERFAMILY SSF55060 205 384 7.92E-45 T 22-04-2016 IPR013750 GHMP kinase, C-terminal domain L21SP4_RS05630 52aaba04ea7f8a3644d277efd64223f2 390 Gene3D G3DSA:3.30.230.10 7 208 5.0E-53 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup L21SP4_RS05630 52aaba04ea7f8a3644d277efd64223f2 390 Pfam PF08544 GHMP kinases C terminal 289 365 8.3E-15 T 22-04-2016 IPR013750 GHMP kinase, C-terminal domain L21SP4_RS05630 52aaba04ea7f8a3644d277efd64223f2 390 SUPERFAMILY SSF54211 5 198 5.09E-43 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold L21SP4_RS05630 52aaba04ea7f8a3644d277efd64223f2 390 Pfam PF10509 Galactokinase galactose-binding signature 13 60 7.6E-15 T 22-04-2016 IPR019539 Galactokinase galactose-binding domain KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 L21SP4_RS05630 52aaba04ea7f8a3644d277efd64223f2 390 PANTHER PTHR10457 18 363 6.8E-91 T 22-04-2016 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 L21SP4_RS05630 52aaba04ea7f8a3644d277efd64223f2 390 Gene3D G3DSA:3.30.70.890 209 384 2.1E-48 T 22-04-2016 IPR013750 GHMP kinase, C-terminal domain L21SP4_RS05630 52aaba04ea7f8a3644d277efd64223f2 390 Pfam PF00288 GHMP kinases N terminal domain 118 182 7.3E-12 T 22-04-2016 IPR006204 GHMP kinase N-terminal domain GO:0005524 L21SP4_RS05630 52aaba04ea7f8a3644d277efd64223f2 390 PRINTS PR00959 Mevalonate kinase family signature 28 52 5.0E-33 T 22-04-2016 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 L21SP4_RS05630 52aaba04ea7f8a3644d277efd64223f2 390 PRINTS PR00959 Mevalonate kinase family signature 163 182 5.0E-33 T 22-04-2016 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 L21SP4_RS05630 52aaba04ea7f8a3644d277efd64223f2 390 PRINTS PR00959 Mevalonate kinase family signature 333 350 5.0E-33 T 22-04-2016 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 L21SP4_RS05630 52aaba04ea7f8a3644d277efd64223f2 390 PRINTS PR00959 Mevalonate kinase family signature 120 142 5.0E-33 T 22-04-2016 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 L21SP4_RS05630 52aaba04ea7f8a3644d277efd64223f2 390 TIGRFAM TIGR00131 gal_kin: galactokinase 16 385 7.9E-77 T 22-04-2016 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 L21SP4_RS05630 52aaba04ea7f8a3644d277efd64223f2 390 PIRSF PIRSF000530 1 389 2.3E-95 T 22-04-2016 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 L21SP4_RS05630 52aaba04ea7f8a3644d277efd64223f2 390 PRINTS PR00473 Galactokinase signature 270 284 2.1E-16 T 22-04-2016 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 L21SP4_RS05630 52aaba04ea7f8a3644d277efd64223f2 390 PRINTS PR00473 Galactokinase signature 30 48 2.1E-16 T 22-04-2016 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 L21SP4_RS05630 52aaba04ea7f8a3644d277efd64223f2 390 PRINTS PR00473 Galactokinase signature 113 131 2.1E-16 T 22-04-2016 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 L21SP4_RS05630 52aaba04ea7f8a3644d277efd64223f2 390 PRINTS PR00473 Galactokinase signature 93 104 2.1E-16 T 22-04-2016 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 L21SP4_RS12105 bff71894b1e7e0da56c5e4d27720947d 295 PANTHER PTHR40590 1 293 2.5E-38 T 22-04-2016 L21SP4_RS12105 bff71894b1e7e0da56c5e4d27720947d 295 Pfam PF01963 TraB family 28 289 1.2E-67 T 22-04-2016 IPR002816 Pheromone shutdown, TraB L21SP4_RS06875 5ecf5b87dbcfcf81795ffd02cd783c6d 99 SUPERFAMILY SSF54928 3 98 1.75E-33 T 22-04-2016 IPR012677 Nucleotide-binding alpha-beta plait domain GO:0000166 L21SP4_RS06875 5ecf5b87dbcfcf81795ffd02cd783c6d 99 Gene3D G3DSA:3.30.70.330 3 95 6.2E-33 T 22-04-2016 IPR012677 Nucleotide-binding alpha-beta plait domain GO:0000166 L21SP4_RS06875 5ecf5b87dbcfcf81795ffd02cd783c6d 99 Pfam PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 3 73 3.7E-23 T 22-04-2016 IPR000504 RNA recognition motif domain GO:0003676 L21SP4_RS06875 5ecf5b87dbcfcf81795ffd02cd783c6d 99 PANTHER PTHR24012 3 94 5.5E-28 T 22-04-2016 L21SP4_RS06875 5ecf5b87dbcfcf81795ffd02cd783c6d 99 SMART SM00360 2 75 2.3E-27 T 22-04-2016 IPR000504 RNA recognition motif domain GO:0003676 L21SP4_RS01265 25a9d9d1815db0632d362a1e5da8bf35 106 SUPERFAMILY SSF50118 1 104 7.63E-30 T 22-04-2016 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor L21SP4_RS01265 25a9d9d1815db0632d362a1e5da8bf35 106 PIRSF PIRSF033490 1 106 5.5E-29 T 22-04-2016 IPR003477 mRNA interferase PemK-like protein GO:0003677 L21SP4_RS01265 25a9d9d1815db0632d362a1e5da8bf35 106 Gene3D G3DSA:2.30.30.110 1 104 1.3E-30 T 22-04-2016 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor L21SP4_RS01265 25a9d9d1815db0632d362a1e5da8bf35 106 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 2 102 8.4E-26 T 22-04-2016 IPR003477 mRNA interferase PemK-like protein GO:0003677 L21SP4_RS01265 25a9d9d1815db0632d362a1e5da8bf35 106 PANTHER PTHR33988 1 106 2.2E-27 T 22-04-2016 L21SP4_RS11465 7daac00ee8ea253acec8afa23aed13e2 946 Gene3D G3DSA:1.20.1580.10 697 823 6.8E-53 T 22-04-2016 L21SP4_RS11465 7daac00ee8ea253acec8afa23aed13e2 946 Hamap MF_00205 UvrABC system protein A [uvrA]. 3 943 21.936 T 22-04-2016 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 L21SP4_RS11465 7daac00ee8ea253acec8afa23aed13e2 946 SUPERFAMILY SSF52540 9 206 1.51E-44 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS11465 7daac00ee8ea253acec8afa23aed13e2 946 SUPERFAMILY SSF52540 435 574 1.51E-44 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS11465 7daac00ee8ea253acec8afa23aed13e2 946 Gene3D G3DSA:3.40.50.300 5 53 2.2E-54 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS11465 7daac00ee8ea253acec8afa23aed13e2 946 Gene3D G3DSA:3.40.50.300 610 676 7.4E-60 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS11465 7daac00ee8ea253acec8afa23aed13e2 946 Gene3D G3DSA:3.40.50.300 483 600 2.2E-54 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS11465 7daac00ee8ea253acec8afa23aed13e2 946 Gene3D G3DSA:3.40.50.300 824 942 7.4E-60 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS11465 7daac00ee8ea253acec8afa23aed13e2 946 Gene3D G3DSA:3.30.1490.20 132 155 7.0E-22 T 22-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 L21SP4_RS11465 7daac00ee8ea253acec8afa23aed13e2 946 Gene3D G3DSA:3.30.1490.20 202 252 7.0E-22 T 22-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 L21SP4_RS11465 7daac00ee8ea253acec8afa23aed13e2 946 Gene3D G3DSA:1.10.8.280 290 411 5.6E-36 T 22-04-2016 L21SP4_RS11465 7daac00ee8ea253acec8afa23aed13e2 946 ProSitePatterns PS00211 ABC transporters family signature. 833 847 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 L21SP4_RS11465 7daac00ee8ea253acec8afa23aed13e2 946 ProSitePatterns PS00211 ABC transporters family signature. 492 506 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 L21SP4_RS11465 7daac00ee8ea253acec8afa23aed13e2 946 Gene3D G3DSA:1.20.1580.10 94 131 7.5E-51 T 22-04-2016 L21SP4_RS11465 7daac00ee8ea253acec8afa23aed13e2 946 Gene3D G3DSA:1.20.1580.10 412 482 7.5E-51 T 22-04-2016 L21SP4_RS11465 7daac00ee8ea253acec8afa23aed13e2 946 Gene3D G3DSA:1.20.1580.10 254 287 7.5E-51 T 22-04-2016 L21SP4_RS11465 7daac00ee8ea253acec8afa23aed13e2 946 PANTHER PTHR32282:SF2 4 945 0.0 T 22-04-2016 L21SP4_RS11465 7daac00ee8ea253acec8afa23aed13e2 946 SUPERFAMILY SSF52540 618 915 4.1E-50 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS11465 7daac00ee8ea253acec8afa23aed13e2 946 PANTHER PTHR32282 4 945 0.0 T 22-04-2016 L21SP4_RS11465 7daac00ee8ea253acec8afa23aed13e2 946 SMART SM00382 636 911 0.0019 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS11465 7daac00ee8ea253acec8afa23aed13e2 946 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 6 928 0.0 T 22-04-2016 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 L21SP4_RS07730 361bdcf8f01f7709e8186082fe0ca801 160 PANTHER PTHR12714 36 154 5.0E-18 T 22-04-2016 L21SP4_RS07730 361bdcf8f01f7709e8186082fe0ca801 160 Pfam PF04191 Phospholipid methyltransferase 54 137 5.1E-8 T 22-04-2016 IPR007318 Phospholipid methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|UniPathway: UPA00753 L21SP4_RS04805 a32d10a5295aafbdecbfd6577726b3ee 140 Pfam PF15891 Nucleoside 2-deoxyribosyltransferase like 4 100 7.5E-10 T 22-04-2016 L21SP4_RS04805 a32d10a5295aafbdecbfd6577726b3ee 140 Gene3D G3DSA:3.40.50.1810 3 130 4.4E-10 T 22-04-2016 IPR007710 Nucleoside 2-deoxyribosyltransferase GO:0009159|GO:0050144|GO:0070694 L21SP4_RS04805 a32d10a5295aafbdecbfd6577726b3ee 140 SUPERFAMILY SSF52309 4 108 2.59E-11 T 22-04-2016 L21SP4_RS01550 8ef1c58f03dfaf773ae0e92d694febb5 427 SUPERFAMILY SSF51126 332 405 8.64E-5 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor L21SP4_RS01550 8ef1c58f03dfaf773ae0e92d694febb5 427 Gene3D G3DSA:2.160.20.10 31 308 3.9E-14 T 22-04-2016 IPR012334 Pectin lyase fold L21SP4_RS01550 8ef1c58f03dfaf773ae0e92d694febb5 427 Gene3D G3DSA:2.160.20.10 333 404 1.2E-4 T 22-04-2016 IPR012334 Pectin lyase fold L21SP4_RS01550 8ef1c58f03dfaf773ae0e92d694febb5 427 SUPERFAMILY SSF51126 18 252 8.05E-19 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor L21SP4_RS01550 8ef1c58f03dfaf773ae0e92d694febb5 427 SUPERFAMILY SSF51126 282 325 8.05E-19 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor L21SP4_RS09735 d9a6854bd56c3e7e7385548688a62b91 471 Pfam PF14319 Transposase zinc-binding domain 34 148 2.7E-20 T 22-04-2016 IPR026889 Transposase zinc-binding domain L21SP4_RS09735 d9a6854bd56c3e7e7385548688a62b91 471 Pfam PF04986 Putative transposase 175 347 5.6E-25 T 22-04-2016 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 L21SP4_RS07990 c1069c352d3b735a61c04c38534dfe57 79 Pfam PF07878 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 2 44 3.0E-7 T 22-04-2016 IPR012869 CopG-like ribbon-helix-helix domain L21SP4_RS07990 c1069c352d3b735a61c04c38534dfe57 79 SUPERFAMILY SSF47598 3 45 3.89E-6 T 22-04-2016 IPR010985 Ribbon-helix-helix GO:0006355 L21SP4_RS08740 6b2d8c74afb66700aedce2cec52adb8b 520 SUPERFAMILY SSF48208 416 515 2.15E-8 T 22-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP4_RS08740 6b2d8c74afb66700aedce2cec52adb8b 520 SUPERFAMILY SSF48208 155 346 8.16E-6 T 22-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP4_RS08740 6b2d8c74afb66700aedce2cec52adb8b 520 Gene3D G3DSA:1.50.10.10 259 477 1.9E-4 T 22-04-2016 IPR012341 Six-hairpin glycosidase GO:0003824 L21SP4_RS07800 b5ca880e12bcf25e02ffbaf768dcc4bd 123 Pfam PF13366 PD-(D/E)XK nuclease superfamily 5 121 2.1E-43 T 22-04-2016 IPR026350 GxxExxY protein L21SP4_RS07800 b5ca880e12bcf25e02ffbaf768dcc4bd 123 TIGRFAM TIGR04256 GxxExxY: GxxExxY protein 5 122 3.3E-45 T 22-04-2016 IPR026350 GxxExxY protein L21SP4_RS00710 657c73b9485409260f7e41591ce9b920 220 Hamap MF_00801 Endonuclease V [nfi]. 11 220 30.958 T 22-04-2016 IPR007581 Endonuclease V GO:0004519|GO:0006281 L21SP4_RS00710 657c73b9485409260f7e41591ce9b920 220 PANTHER PTHR28511 15 215 1.7E-71 T 22-04-2016 L21SP4_RS00710 657c73b9485409260f7e41591ce9b920 220 Pfam PF04493 Endonuclease V 21 212 1.7E-70 T 22-04-2016 IPR007581 Endonuclease V GO:0004519|GO:0006281 L21SP4_RS00710 657c73b9485409260f7e41591ce9b920 220 PANTHER PTHR28511:SF1 15 215 1.7E-71 T 22-04-2016 L21SP4_RS08930 7341032b220e09e4889e691bcec2b427 169 SUPERFAMILY SSF81301 2 158 8.5E-12 T 22-04-2016 L21SP4_RS07070 96e41608951f2d598f25d5de23f17dea 339 Gene3D G3DSA:3.40.50.10750 140 304 3.1E-54 T 22-04-2016 L21SP4_RS07070 96e41608951f2d598f25d5de23f17dea 339 PANTHER PTHR23406:SF3 1 333 3.3E-52 T 22-04-2016 L21SP4_RS07070 96e41608951f2d598f25d5de23f17dea 339 TIGRFAM TIGR00651 pta: phosphate acetyltransferase 21 328 4.1E-104 T 22-04-2016 IPR004614 Phosphate acetyltransferase GO:0016407 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637|UniPathway: UPA00340 L21SP4_RS07070 96e41608951f2d598f25d5de23f17dea 339 PIRSF PIRSF000428 1 334 5.7E-96 T 22-04-2016 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637|UniPathway: UPA00340 L21SP4_RS07070 96e41608951f2d598f25d5de23f17dea 339 PANTHER PTHR23406 1 333 3.3E-52 T 22-04-2016 L21SP4_RS07070 96e41608951f2d598f25d5de23f17dea 339 Pfam PF01515 Phosphate acetyl/butaryl transferase 6 328 4.4E-112 T 22-04-2016 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637|UniPathway: UPA00340 L21SP4_RS07070 96e41608951f2d598f25d5de23f17dea 339 SUPERFAMILY SSF53659 6 331 1.32E-83 T 22-04-2016 L21SP4_RS04170 ec5a98c7605727057bcf5f0d0e381cd8 539 Pfam PF00342 Phosphoglucose isomerase 53 531 5.2E-209 T 22-04-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 L21SP4_RS04170 ec5a98c7605727057bcf5f0d0e381cd8 539 PANTHER PTHR11469 1 539 3.8E-288 T 22-04-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 L21SP4_RS04170 ec5a98c7605727057bcf5f0d0e381cd8 539 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 265 278 - T 22-04-2016 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 L21SP4_RS04170 ec5a98c7605727057bcf5f0d0e381cd8 539 Gene3D G3DSA:3.40.50.10490 100 290 1.6E-75 T 22-04-2016 L21SP4_RS04170 ec5a98c7605727057bcf5f0d0e381cd8 539 Gene3D G3DSA:3.40.50.10490 12 99 2.8E-137 T 22-04-2016 L21SP4_RS04170 ec5a98c7605727057bcf5f0d0e381cd8 539 Gene3D G3DSA:3.40.50.10490 293 498 2.8E-137 T 22-04-2016 L21SP4_RS04170 ec5a98c7605727057bcf5f0d0e381cd8 539 SUPERFAMILY SSF53697 10 537 1.58E-206 T 22-04-2016 L21SP4_RS04170 ec5a98c7605727057bcf5f0d0e381cd8 539 Gene3D G3DSA:1.10.1390.10 499 538 2.5E-16 T 22-04-2016 IPR023096 Phosphoglucose isomerase, C-terminal GO:0004347|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 L21SP4_RS04170 ec5a98c7605727057bcf5f0d0e381cd8 539 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 47 516 40.764 T 22-04-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 L21SP4_RS04170 ec5a98c7605727057bcf5f0d0e381cd8 539 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 489 506 - T 22-04-2016 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 L21SP4_RS04170 ec5a98c7605727057bcf5f0d0e381cd8 539 PRINTS PR00662 Glucose-6-phosphate isomerase signature 457 475 1.2E-53 T 22-04-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 L21SP4_RS04170 ec5a98c7605727057bcf5f0d0e381cd8 539 PRINTS PR00662 Glucose-6-phosphate isomerase signature 151 170 1.2E-53 T 22-04-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 L21SP4_RS04170 ec5a98c7605727057bcf5f0d0e381cd8 539 PRINTS PR00662 Glucose-6-phosphate isomerase signature 261 279 1.2E-53 T 22-04-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 L21SP4_RS04170 ec5a98c7605727057bcf5f0d0e381cd8 539 PRINTS PR00662 Glucose-6-phosphate isomerase signature 338 359 1.2E-53 T 22-04-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 L21SP4_RS04170 ec5a98c7605727057bcf5f0d0e381cd8 539 PRINTS PR00662 Glucose-6-phosphate isomerase signature 489 502 1.2E-53 T 22-04-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 L21SP4_RS04170 ec5a98c7605727057bcf5f0d0e381cd8 539 PRINTS PR00662 Glucose-6-phosphate isomerase signature 475 489 1.2E-53 T 22-04-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 L21SP4_RS09795 8711434584b7394625a0292302dcf70c 494 Pfam PF03050 Transposase IS66 family 175 456 1.4E-59 T 22-04-2016 IPR004291 Transposase, IS66 L21SP4_RS09795 8711434584b7394625a0292302dcf70c 494 PANTHER PTHR33678 17 494 1.7E-127 T 22-04-2016 L21SP4_RS09795 8711434584b7394625a0292302dcf70c 494 Pfam PF13005 zinc-finger binding domain of transposase IS66 116 159 2.1E-7 T 22-04-2016 IPR024474 Zinc-finger binding domain of transposase IS66 L21SP4_RS09795 8711434584b7394625a0292302dcf70c 494 PANTHER PTHR33678:SF2 17 494 1.7E-127 T 22-04-2016 L21SP4_RS12050 f8fbbd769f2a29229056bab547103b75 254 PANTHER PTHR10342:SF237 155 223 8.6E-50 T 22-04-2016 L21SP4_RS12050 f8fbbd769f2a29229056bab547103b75 254 PANTHER PTHR10342:SF237 1 135 8.6E-50 T 22-04-2016 L21SP4_RS12050 f8fbbd769f2a29229056bab547103b75 254 SUPERFAMILY SSF53649 1 220 1.55E-47 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS12050 f8fbbd769f2a29229056bab547103b75 254 Pfam PF16347 Domain of unknown function (DUF4976) 160 204 1.8E-7 T 22-04-2016 IPR032506 Domain of unknown function DUF4976 L21SP4_RS12050 f8fbbd769f2a29229056bab547103b75 254 Pfam PF00884 Sulfatase 1 60 2.1E-11 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS12050 f8fbbd769f2a29229056bab547103b75 254 PANTHER PTHR10342 155 223 8.6E-50 T 22-04-2016 L21SP4_RS12050 f8fbbd769f2a29229056bab547103b75 254 PANTHER PTHR10342 1 135 8.6E-50 T 22-04-2016 L21SP4_RS12050 f8fbbd769f2a29229056bab547103b75 254 Gene3D G3DSA:3.30.1120.10 105 121 3.5E-19 T 22-04-2016 L21SP4_RS12050 f8fbbd769f2a29229056bab547103b75 254 Gene3D G3DSA:3.30.1120.10 161 215 3.5E-19 T 22-04-2016 L21SP4_RS12050 f8fbbd769f2a29229056bab547103b75 254 Gene3D G3DSA:3.40.720.10 1 104 3.2E-25 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS06955 63c2df185ede32f4200c1c8de26b0997 298 PANTHER PTHR11040 1 292 2.2E-91 T 22-04-2016 L21SP4_RS06955 63c2df185ede32f4200c1c8de26b0997 298 Hamap MF_00548 Zinc transporter ZupT [zupT]. 4 298 32.28 T 22-04-2016 IPR023498 Zinc transporter ZupT L21SP4_RS06955 63c2df185ede32f4200c1c8de26b0997 298 Pfam PF02535 ZIP Zinc transporter 8 292 4.9E-32 T 22-04-2016 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 L21SP4_RS06955 63c2df185ede32f4200c1c8de26b0997 298 PANTHER PTHR11040:SF56 1 292 2.2E-91 T 22-04-2016 L21SP4_RS07040 e2b2549c238cddb36a4b70a0e5bef9b5 269 Pfam PF07796 Protein of unknown function (DUF1638) 51 236 1.1E-37 T 22-04-2016 IPR012437 Domain of unknown function DUF1638 L21SP4_RS08475 bfc5c282c32de38691386c4190625fa9 50 Pfam PF00471 Ribosomal protein L33 4 50 3.8E-23 T 22-04-2016 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS08475 bfc5c282c32de38691386c4190625fa9 50 PANTHER PTHR15238 3 49 3.7E-20 T 22-04-2016 L21SP4_RS08475 bfc5c282c32de38691386c4190625fa9 50 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 3 50 2.8E-22 T 22-04-2016 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS08475 bfc5c282c32de38691386c4190625fa9 50 PANTHER PTHR15238:SF3 3 49 3.7E-20 T 22-04-2016 L21SP4_RS08475 bfc5c282c32de38691386c4190625fa9 50 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 2 50 18.242 T 22-04-2016 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS08475 bfc5c282c32de38691386c4190625fa9 50 SUPERFAMILY SSF57829 3 50 2.32E-19 T 22-04-2016 IPR011332 Zinc-binding ribosomal protein GO:0006412 L21SP4_RS03040 5f6b9f6bd4408b7a1e0f095ec52ee2a7 482 SMART SM00481 27 122 0.0079 T 22-04-2016 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 L21SP4_RS03040 5f6b9f6bd4408b7a1e0f095ec52ee2a7 482 SUPERFAMILY SSF89550 238 304 7.85E-13 T 22-04-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 L21SP4_RS03040 5f6b9f6bd4408b7a1e0f095ec52ee2a7 482 SUPERFAMILY SSF89550 333 377 7.85E-13 T 22-04-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 L21SP4_RS03040 5f6b9f6bd4408b7a1e0f095ec52ee2a7 482 SUPERFAMILY SSF89550 24 127 7.85E-13 T 22-04-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 L21SP4_RS03040 5f6b9f6bd4408b7a1e0f095ec52ee2a7 482 Gene3D G3DSA:3.20.20.140 25 118 3.6E-6 T 22-04-2016 L21SP4_RS01540 5d30527e78033b1fdb5faf3e0d35ac07 187 TIGRFAM TIGR04258 4helix_suffix: four helix bundle suffix domain 135 182 2.7E-20 T 22-04-2016 IPR026354 Four helix bundle suffix domain L21SP4_RS01540 5d30527e78033b1fdb5faf3e0d35ac07 187 TIGRFAM TIGR02436 TIGR02436: four helix bundle protein 19 88 5.0E-6 T 22-04-2016 IPR012657 23S rRNA-intervening sequence protein L21SP4_RS01540 5d30527e78033b1fdb5faf3e0d35ac07 187 SUPERFAMILY SSF158446 11 106 1.02E-17 T 22-04-2016 L21SP4_RS01540 5d30527e78033b1fdb5faf3e0d35ac07 187 Gene3D G3DSA:1.20.1440.60 12 87 8.2E-4 T 22-04-2016 IPR012657 23S rRNA-intervening sequence protein L21SP4_RS10720 179b6f15dd0b5e1b6bccd869a1ed95e2 218 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 8 197 2.2E-45 T 22-04-2016 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 UniPathway: UPA00085 L21SP4_RS10720 179b6f15dd0b5e1b6bccd869a1ed95e2 218 SMART SM01207 12 191 2.8E-70 T 22-04-2016 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 UniPathway: UPA00085 L21SP4_RS10720 179b6f15dd0b5e1b6bccd869a1ed95e2 218 Pfam PF02660 Glycerol-3-phosphate acyltransferase 14 190 9.7E-48 T 22-04-2016 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 UniPathway: UPA00085 L21SP4_RS10720 179b6f15dd0b5e1b6bccd869a1ed95e2 218 PANTHER PTHR30309:SF0 2 198 5.3E-59 T 22-04-2016 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 UniPathway: UPA00085 L21SP4_RS10720 179b6f15dd0b5e1b6bccd869a1ed95e2 218 PANTHER PTHR30309 2 198 5.3E-59 T 22-04-2016 L21SP4_RS10720 179b6f15dd0b5e1b6bccd869a1ed95e2 218 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 9 199 19.351 T 22-04-2016 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 UniPathway: UPA00085 L21SP4_RS04370 c32d793cf3798481aad3a0510fc490d1 83 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 1 58 7.0E-9 T 22-04-2016 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain L21SP4_RS04370 c32d793cf3798481aad3a0510fc490d1 83 SMART SM00834 1 48 0.0019 T 22-04-2016 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain L21SP4_RS04370 c32d793cf3798481aad3a0510fc490d1 83 Pfam PF09723 Zinc ribbon domain 1 45 3.8E-10 T 22-04-2016 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain L21SP4_RS00425 c65feb01853632b570c4e9294cec5dba 170 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 4 170 19.127 T 22-04-2016 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 L21SP4_RS00425 c65feb01853632b570c4e9294cec5dba 170 SUPERFAMILY SSF55144 11 170 3.84E-37 T 22-04-2016 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase L21SP4_RS00425 c65feb01853632b570c4e9294cec5dba 170 PANTHER PTHR35561 19 170 2.9E-31 T 22-04-2016 L21SP4_RS00425 c65feb01853632b570c4e9294cec5dba 170 Pfam PF13563 2'-5' RNA ligase superfamily 21 151 7.3E-17 T 22-04-2016 L21SP4_RS00425 c65feb01853632b570c4e9294cec5dba 170 Gene3D G3DSA:3.90.1140.10 7 170 9.9E-46 T 22-04-2016 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase L21SP4_RS00425 c65feb01853632b570c4e9294cec5dba 170 PANTHER PTHR35561:SF1 19 170 2.9E-31 T 22-04-2016 L21SP4_RS00425 c65feb01853632b570c4e9294cec5dba 170 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 12 170 1.1E-37 T 22-04-2016 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 L21SP4_RS11410 d9f024ba25b7be66ee3220428688476d 511 PANTHER PTHR10342 2 444 2.6E-91 T 22-04-2016 L21SP4_RS11410 d9f024ba25b7be66ee3220428688476d 511 Gene3D G3DSA:3.40.720.10 2 371 3.0E-90 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS11410 d9f024ba25b7be66ee3220428688476d 511 SUPERFAMILY SSF53649 4 444 7.72E-104 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS11410 d9f024ba25b7be66ee3220428688476d 511 Pfam PF00884 Sulfatase 5 353 2.1E-54 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS11410 d9f024ba25b7be66ee3220428688476d 511 Gene3D G3DSA:3.30.1120.10 380 444 1.2E-7 T 22-04-2016 L21SP4_RS11180 9e14f4a985168e7a4f783b3398f2a59b 199 SUPERFAMILY SSF51161 12 164 6.25E-40 T 22-04-2016 IPR011004 Trimeric LpxA-like L21SP4_RS11180 9e14f4a985168e7a4f783b3398f2a59b 199 PANTHER PTHR23416:SF53 14 191 4.6E-34 T 22-04-2016 L21SP4_RS11180 9e14f4a985168e7a4f783b3398f2a59b 199 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 50 84 9.6E-7 T 22-04-2016 IPR001451 Hexapeptide repeat L21SP4_RS11180 9e14f4a985168e7a4f783b3398f2a59b 199 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 111 145 1.0E-8 T 22-04-2016 IPR001451 Hexapeptide repeat L21SP4_RS11180 9e14f4a985168e7a4f783b3398f2a59b 199 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 16 47 7.7E-8 T 22-04-2016 IPR001451 Hexapeptide repeat L21SP4_RS11180 9e14f4a985168e7a4f783b3398f2a59b 199 PANTHER PTHR23416 14 191 4.6E-34 T 22-04-2016 L21SP4_RS11180 9e14f4a985168e7a4f783b3398f2a59b 199 Gene3D G3DSA:2.160.10.10 14 182 7.4E-40 T 22-04-2016 L21SP4_RS06110 3b9672ff296c475926ed3fb9de53241d 134 SUPERFAMILY SSF47226 31 125 1.07E-14 T 22-04-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 L21SP4_RS06110 3b9672ff296c475926ed3fb9de53241d 134 Gene3D G3DSA:1.20.120.160 44 123 2.9E-13 T 22-04-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 L21SP4_RS06110 3b9672ff296c475926ed3fb9de53241d 134 Pfam PF01627 Hpt domain 49 121 9.0E-13 T 22-04-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 L21SP4_RS03290 fc731b72a9b2f867a64bf5545cb0d1e6 1118 SUPERFAMILY SSF51556 908 955 3.7E-5 T 22-04-2016 IPR032466 Metal-dependent hydrolase L21SP4_RS03290 fc731b72a9b2f867a64bf5545cb0d1e6 1118 SUPERFAMILY SSF51556 1001 1025 3.7E-5 T 22-04-2016 IPR032466 Metal-dependent hydrolase L21SP4_RS03290 fc731b72a9b2f867a64bf5545cb0d1e6 1118 SUPERFAMILY SSF51556 753 779 3.7E-5 T 22-04-2016 IPR032466 Metal-dependent hydrolase L21SP4_RS03290 fc731b72a9b2f867a64bf5545cb0d1e6 1118 SUPERFAMILY SSF51556 818 873 3.7E-5 T 22-04-2016 IPR032466 Metal-dependent hydrolase L21SP4_RS03290 fc731b72a9b2f867a64bf5545cb0d1e6 1118 Gene3D G3DSA:2.30.40.10 1001 1052 5.6E-6 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 L21SP4_RS03290 fc731b72a9b2f867a64bf5545cb0d1e6 1118 Gene3D G3DSA:2.30.40.10 922 953 5.6E-6 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 L21SP4_RS03290 fc731b72a9b2f867a64bf5545cb0d1e6 1118 Gene3D G3DSA:2.30.40.10 117 180 5.9E-6 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 L21SP4_RS03290 fc731b72a9b2f867a64bf5545cb0d1e6 1118 Gene3D G3DSA:2.30.40.10 37 70 8.0E-5 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 L21SP4_RS03975 161e662aa57d83b1c5df3fe0d2b568c7 148 PANTHER PTHR34297 7 143 6.6E-27 T 22-04-2016 L21SP4_RS03975 161e662aa57d83b1c5df3fe0d2b568c7 148 Pfam PF03780 Asp23 family, cell envelope-related function 29 134 8.3E-28 T 22-04-2016 IPR005531 Alkaline shock protein Asp23 L21SP4_RS03975 161e662aa57d83b1c5df3fe0d2b568c7 148 PANTHER PTHR34297:SF1 7 143 6.6E-27 T 22-04-2016 L21SP4_RS09210 88e9aa626cc98213c3f84a2258b41b4d 416 PANTHER PTHR30489 1 416 2.2E-37 T 22-04-2016 L21SP4_RS09210 88e9aa626cc98213c3f84a2258b41b4d 416 Pfam PF02687 FtsX-like permease family 284 407 3.4E-18 T 22-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 L21SP4_RS06700 cb5d7f8942d2d762b472bbc57da35da0 494 PANTHER PTHR33678 17 494 1.1E-127 T 22-04-2016 L21SP4_RS06700 cb5d7f8942d2d762b472bbc57da35da0 494 PANTHER PTHR33678:SF2 17 494 1.1E-127 T 22-04-2016 L21SP4_RS06700 cb5d7f8942d2d762b472bbc57da35da0 494 Pfam PF13005 zinc-finger binding domain of transposase IS66 116 159 2.1E-7 T 22-04-2016 IPR024474 Zinc-finger binding domain of transposase IS66 L21SP4_RS06700 cb5d7f8942d2d762b472bbc57da35da0 494 Pfam PF03050 Transposase IS66 family 175 456 4.6E-60 T 22-04-2016 IPR004291 Transposase, IS66 L21SP4_RS04895 b6153dd3cd422d87cab4169e6e3c7ddb 347 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 3 326 1.2E-107 T 22-04-2016 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 L21SP4_RS04895 b6153dd3cd422d87cab4169e6e3c7ddb 347 PANTHER PTHR11735 1 342 1.3E-119 T 22-04-2016 L21SP4_RS04895 b6153dd3cd422d87cab4169e6e3c7ddb 347 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 1 346 53.587 T 22-04-2016 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 L21SP4_RS04895 b6153dd3cd422d87cab4169e6e3c7ddb 347 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 4 321 2.3E-90 T 22-04-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 L21SP4_RS04895 b6153dd3cd422d87cab4169e6e3c7ddb 347 PANTHER PTHR11735:SF6 1 342 1.3E-119 T 22-04-2016 L21SP4_RS04895 b6153dd3cd422d87cab4169e6e3c7ddb 347 SUPERFAMILY SSF53067 1 322 3.4E-37 T 22-04-2016 L21SP4_RS04895 b6153dd3cd422d87cab4169e6e3c7ddb 347 Gene3D G3DSA:3.30.420.40 1 163 4.6E-40 T 22-04-2016 L21SP4_RS04895 b6153dd3cd422d87cab4169e6e3c7ddb 347 Pfam PF00814 Glycoprotease family 24 321 8.4E-85 T 22-04-2016 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 L21SP4_RS04895 b6153dd3cd422d87cab4169e6e3c7ddb 347 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 158 179 1.4E-33 T 22-04-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 L21SP4_RS04895 b6153dd3cd422d87cab4169e6e3c7ddb 347 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 76 96 1.4E-33 T 22-04-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 L21SP4_RS04895 b6153dd3cd422d87cab4169e6e3c7ddb 347 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 4 17 1.4E-33 T 22-04-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 L21SP4_RS04895 b6153dd3cd422d87cab4169e6e3c7ddb 347 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 97 116 1.4E-33 T 22-04-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 L21SP4_RS04895 b6153dd3cd422d87cab4169e6e3c7ddb 347 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 278 287 1.4E-33 T 22-04-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 L21SP4_RS04130 ee5688bf9ddfb4f55e3873e631cc4fb0 136 Gene3D G3DSA:1.25.40.10 19 119 4.3E-10 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS04130 ee5688bf9ddfb4f55e3873e631cc4fb0 136 SUPERFAMILY SSF48452 16 113 6.75E-12 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS02970 db8df14ba9cf3e331b7ae39894f46a8e 420 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 216 415 2.6E-20 T 22-04-2016 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 L21SP4_RS02970 db8df14ba9cf3e331b7ae39894f46a8e 420 SUPERFAMILY SSF51726 116 417 3.84E-37 T 22-04-2016 L21SP4_RS02970 db8df14ba9cf3e331b7ae39894f46a8e 420 SUPERFAMILY SSF51726 3 78 3.84E-37 T 22-04-2016 L21SP4_RS02970 db8df14ba9cf3e331b7ae39894f46a8e 420 Gene3D G3DSA:3.20.20.210 3 79 2.5E-41 T 22-04-2016 L21SP4_RS02970 db8df14ba9cf3e331b7ae39894f46a8e 420 Gene3D G3DSA:3.20.20.210 117 416 2.5E-41 T 22-04-2016 L21SP4_RS07910 4bb5d0a98ba7b317f37ab8505033611f 235 Pfam PF04773 FecR protein 51 139 1.1E-6 T 22-04-2016 IPR006860 FecR protein L21SP4_RS01315 ea708534b2f72f43e3aa785405eace38 365 Pfam PF00482 Type II secretion system (T2SS), protein F 233 355 2.5E-27 T 22-04-2016 IPR018076 Type II secretion system F domain L21SP4_RS01315 ea708534b2f72f43e3aa785405eace38 365 Pfam PF00482 Type II secretion system (T2SS), protein F 30 153 1.6E-27 T 22-04-2016 IPR018076 Type II secretion system F domain L21SP4_RS01315 ea708534b2f72f43e3aa785405eace38 365 PANTHER PTHR30012:SF0 19 364 4.0E-123 T 22-04-2016 L21SP4_RS01315 ea708534b2f72f43e3aa785405eace38 365 PANTHER PTHR30012 19 364 4.0E-123 T 22-04-2016 L21SP4_RS01315 ea708534b2f72f43e3aa785405eace38 365 PRINTS PR00812 Bacterial general secretion pathway protein F signature 328 342 4.09E-15 T 22-04-2016 IPR003004 GspF/PilC family L21SP4_RS01315 ea708534b2f72f43e3aa785405eace38 365 PRINTS PR00812 Bacterial general secretion pathway protein F signature 344 363 4.09E-15 T 22-04-2016 IPR003004 GspF/PilC family L21SP4_RS01315 ea708534b2f72f43e3aa785405eace38 365 PRINTS PR00812 Bacterial general secretion pathway protein F signature 125 153 4.09E-15 T 22-04-2016 IPR003004 GspF/PilC family L21SP4_RS01315 ea708534b2f72f43e3aa785405eace38 365 PRINTS PR00812 Bacterial general secretion pathway protein F signature 26 38 4.09E-15 T 22-04-2016 IPR003004 GspF/PilC family L21SP4_RS01315 ea708534b2f72f43e3aa785405eace38 365 ProSitePatterns PS00874 Bacterial type II secretion system protein F signature. 125 153 - T 22-04-2016 IPR001992 Type II secretion system conserved site GO:0009306|GO:0016020 L21SP4_RS09270 7f1f528aae3428848c4b93492f7e91c9 255 Pfam PF10670 Domain of unknown function (DUF4198) 20 225 6.7E-50 T 22-04-2016 IPR019613 Protein of unknown function DUF4198 L21SP4_RS01595 32938906357421ce790920c4d533b169 397 Gene3D G3DSA:2.160.20.10 41 392 1.3E-16 T 22-04-2016 IPR012334 Pectin lyase fold L21SP4_RS01595 32938906357421ce790920c4d533b169 397 Pfam PF12708 Pectate lyase superfamily protein 44 278 5.2E-8 T 22-04-2016 IPR024535 Pectate lyase superfamily protein L21SP4_RS01595 32938906357421ce790920c4d533b169 397 SUPERFAMILY SSF51126 30 396 1.26E-23 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor L21SP4_RS04715 88dfd5229d71f57543e00e39887b47cd 238 Pfam PF09983 Uncharacterized protein conserved in bacteria C-term(DUF2220) 87 232 1.2E-6 T 22-04-2016 IPR024534 Domain of unknown function DUF2220 L21SP4_RS11115 23769080e5cce0bd60dad2504503d40e 673 Gene3D G3DSA:1.25.40.10 513 657 1.9E-15 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS11115 23769080e5cce0bd60dad2504503d40e 673 Pfam PF13414 TPR repeat 526 557 1.2E-6 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS11115 23769080e5cce0bd60dad2504503d40e 673 SUPERFAMILY SSF48452 517 657 1.67E-11 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS11115 23769080e5cce0bd60dad2504503d40e 673 Pfam PF04932 O-Antigen ligase 222 408 1.7E-13 T 22-04-2016 IPR007016 O-antigen ligase-related L21SP4_RS04800 ddbc3e19754913436b172c96fe5df11c 214 SUPERFAMILY SSF143081 2 208 1.31E-49 T 22-04-2016 IPR003738 SOS response associated peptidase (SRAP) KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- L21SP4_RS04800 ddbc3e19754913436b172c96fe5df11c 214 Gene3D G3DSA:3.90.1680.10 1 210 6.4E-49 T 22-04-2016 IPR003738 SOS response associated peptidase (SRAP) KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- L21SP4_RS04800 ddbc3e19754913436b172c96fe5df11c 214 PANTHER PTHR13604 2 210 2.5E-46 T 22-04-2016 IPR003738 SOS response associated peptidase (SRAP) KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- L21SP4_RS04800 ddbc3e19754913436b172c96fe5df11c 214 Pfam PF02586 SOS response associated peptidase (SRAP) 1 201 1.8E-43 T 22-04-2016 IPR003738 SOS response associated peptidase (SRAP) KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- L21SP4_RS03005 6de88bcec1f6e170853f3eb131eef28d 127 SUPERFAMILY SSF52172 3 125 2.99E-22 T 22-04-2016 IPR011006 CheY-like superfamily L21SP4_RS03005 6de88bcec1f6e170853f3eb131eef28d 127 SMART SM00448 5 121 3.7E-13 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 L21SP4_RS03005 6de88bcec1f6e170853f3eb131eef28d 127 PANTHER PTHR26402 5 93 4.1E-18 T 22-04-2016 L21SP4_RS03005 6de88bcec1f6e170853f3eb131eef28d 127 Gene3D G3DSA:3.40.50.2300 3 125 7.1E-24 T 22-04-2016 L21SP4_RS03005 6de88bcec1f6e170853f3eb131eef28d 127 Pfam PF00072 Response regulator receiver domain 7 109 3.2E-15 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 L21SP4_RS09230 c635bff07d0aa4aca570c5ef1ba621d0 243 Pfam PF03740 Pyridoxal phosphate biosynthesis protein PdxJ 3 235 7.4E-94 T 22-04-2016 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2|UniPathway: UPA00244 L21SP4_RS09230 c635bff07d0aa4aca570c5ef1ba621d0 243 PANTHER PTHR30456 1 242 1.6E-114 T 22-04-2016 L21SP4_RS09230 c635bff07d0aa4aca570c5ef1ba621d0 243 Hamap MF_00279 Pyridoxine 5'-phosphate synthase [pdxJ]. 1 241 111.205 T 22-04-2016 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2|UniPathway: UPA00244 L21SP4_RS09230 c635bff07d0aa4aca570c5ef1ba621d0 243 Gene3D G3DSA:3.20.20.70 1 237 7.0E-98 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP4_RS09230 c635bff07d0aa4aca570c5ef1ba621d0 243 SUPERFAMILY SSF63892 1 237 3.79E-90 T 22-04-2016 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2|UniPathway: UPA00244 L21SP4_RS09230 c635bff07d0aa4aca570c5ef1ba621d0 243 PANTHER PTHR30456:SF0 1 242 1.6E-114 T 22-04-2016 L21SP4_RS09230 c635bff07d0aa4aca570c5ef1ba621d0 243 TIGRFAM TIGR00559 pdxJ: pyridoxine 5'-phosphate synthase 3 235 3.7E-83 T 22-04-2016 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2|UniPathway: UPA00244 L21SP4_RS02015 ebcdd7db6de4422b7308e5360c04a32a 1110 SUPERFAMILY SSF49785 933 1052 1.91E-22 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS02015 ebcdd7db6de4422b7308e5360c04a32a 1110 Pfam PF17132 alpha-L-rhamnosidase 37 890 6.5E-179 T 22-04-2016 IPR033400 Alpha-L-rhamnosidase RhaM L21SP4_RS02015 ebcdd7db6de4422b7308e5360c04a32a 1110 Gene3D G3DSA:2.60.120.260 960 1043 6.5E-16 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS02015 ebcdd7db6de4422b7308e5360c04a32a 1110 PANTHER PTHR22925 43 188 3.8E-56 T 22-04-2016 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 L21SP4_RS02015 ebcdd7db6de4422b7308e5360c04a32a 1110 PANTHER PTHR22925 273 284 3.8E-56 T 22-04-2016 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 L21SP4_RS02015 ebcdd7db6de4422b7308e5360c04a32a 1110 PANTHER PTHR22925 331 549 3.8E-56 T 22-04-2016 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 L21SP4_RS02015 ebcdd7db6de4422b7308e5360c04a32a 1110 PANTHER PTHR22925:SF40 43 188 3.8E-56 T 22-04-2016 L21SP4_RS02015 ebcdd7db6de4422b7308e5360c04a32a 1110 PANTHER PTHR22925:SF40 273 284 3.8E-56 T 22-04-2016 L21SP4_RS02015 ebcdd7db6de4422b7308e5360c04a32a 1110 PANTHER PTHR22925:SF40 331 549 3.8E-56 T 22-04-2016 L21SP4_RS01930 a4c034dc4344712d8c4ea96479ced250 166 PANTHER PTHR30615 108 166 6.4E-18 T 22-04-2016 L21SP4_RS01930 a4c034dc4344712d8c4ea96479ced250 166 PANTHER PTHR30615 1 91 6.4E-18 T 22-04-2016 L21SP4_RS01930 a4c034dc4344712d8c4ea96479ced250 166 Pfam PF01894 Uncharacterised protein family UPF0047 21 158 1.9E-31 T 22-04-2016 IPR001602 Uncharacterised protein family UPF0047 L21SP4_RS01930 a4c034dc4344712d8c4ea96479ced250 166 Gene3D G3DSA:2.60.120.460 1 166 1.4E-33 T 22-04-2016 IPR001602 Uncharacterised protein family UPF0047 L21SP4_RS01930 a4c034dc4344712d8c4ea96479ced250 166 SUPERFAMILY SSF111038 1 166 1.22E-26 T 22-04-2016 IPR001602 Uncharacterised protein family UPF0047 L21SP4_RS01930 a4c034dc4344712d8c4ea96479ced250 166 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 18 166 1.5E-20 T 22-04-2016 IPR001602 Uncharacterised protein family UPF0047 L21SP4_RS01485 50c58f3eeadfd4c7c26cb24f6ead5ac3 273 Gene3D G3DSA:2.50.20.10 18 266 6.4E-58 T 22-04-2016 L21SP4_RS01485 50c58f3eeadfd4c7c26cb24f6ead5ac3 273 Pfam PF17131 Outer membrane lipoprotein-sorting protein 84 266 3.1E-53 T 22-04-2016 IPR033399 Putative outer membrane lipoprotein-sorting protein L21SP4_RS02680 f5d438f8172bbad3cff69d1894bfbe1a 398 PANTHER PTHR33546 62 223 2.0E-22 T 22-04-2016 L21SP4_RS02680 f5d438f8172bbad3cff69d1894bfbe1a 398 Pfam PF06439 Domain of Unknown Function (DUF1080) 23 223 1.1E-31 T 22-04-2016 IPR010496 Domain of unknown function DUF1080 L21SP4_RS02680 f5d438f8172bbad3cff69d1894bfbe1a 398 PANTHER PTHR33546:SF1 62 223 2.0E-22 T 22-04-2016 L21SP4_RS11835 42f39048d996f8231cec81a252093c8e 240 Pfam PF13276 HTH-like domain 3 50 1.1E-6 T 22-04-2016 IPR025948 HTH-like domain L21SP4_RS11835 42f39048d996f8231cec81a252093c8e 240 Pfam PF00665 Integrase core domain 72 184 4.9E-21 T 22-04-2016 IPR001584 Integrase, catalytic core GO:0015074 L21SP4_RS11835 42f39048d996f8231cec81a252093c8e 240 Gene3D G3DSA:3.30.420.10 69 224 2.8E-31 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS11835 42f39048d996f8231cec81a252093c8e 240 SUPERFAMILY SSF53098 72 234 9.11E-46 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS11835 42f39048d996f8231cec81a252093c8e 240 PANTHER PTHR32552 23 226 4.4E-25 T 22-04-2016 L21SP4_RS02115 36d07f36fa284497025fa98c78cc0931 132 Pfam PF01850 PIN domain 3 126 3.5E-11 T 22-04-2016 IPR002716 PIN domain L21SP4_RS02115 36d07f36fa284497025fa98c78cc0931 132 Gene3D G3DSA:3.40.50.1010 1 78 4.3E-5 T 22-04-2016 IPR029060 PIN domain-like L21SP4_RS02115 36d07f36fa284497025fa98c78cc0931 132 SUPERFAMILY SSF88723 1 122 1.15E-15 T 22-04-2016 IPR029060 PIN domain-like L21SP4_RS01180 10fcf14560239a8142fbbb7aa7cdc4e7 80 Gene3D G3DSA:1.10.1200.10 3 75 5.0E-33 T 22-04-2016 IPR009081 Phosphopantetheine binding ACP domain L21SP4_RS01180 10fcf14560239a8142fbbb7aa7cdc4e7 80 Hamap MF_01217 Acyl carrier protein [acpP]. 2 76 22.193 T 22-04-2016 IPR003231 Acyl carrier protein (ACP) GO:0006633 UniPathway: UPA00094 L21SP4_RS01180 10fcf14560239a8142fbbb7aa7cdc4e7 80 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 40 75 6.0E-10 T 22-04-2016 IPR003231 Acyl carrier protein (ACP) GO:0006633 UniPathway: UPA00094 L21SP4_RS01180 10fcf14560239a8142fbbb7aa7cdc4e7 80 PANTHER PTHR20863 4 71 2.4E-28 T 22-04-2016 L21SP4_RS01180 10fcf14560239a8142fbbb7aa7cdc4e7 80 SMART SM00823 Phosphopantetheine attachment site 4 62 0.004 T 22-04-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 L21SP4_RS01180 10fcf14560239a8142fbbb7aa7cdc4e7 80 Pfam PF00550 Phosphopantetheine attachment site 5 72 9.1E-18 T 22-04-2016 IPR009081 Phosphopantetheine binding ACP domain L21SP4_RS01180 10fcf14560239a8142fbbb7aa7cdc4e7 80 ProSitePatterns PS00012 Phosphopantetheine attachment site. 31 46 - T 22-04-2016 IPR006162 Phosphopantetheine attachment site L21SP4_RS01180 10fcf14560239a8142fbbb7aa7cdc4e7 80 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 2 75 3.0E-34 T 22-04-2016 IPR003231 Acyl carrier protein (ACP) GO:0006633 UniPathway: UPA00094 L21SP4_RS01180 10fcf14560239a8142fbbb7aa7cdc4e7 80 SUPERFAMILY SSF47336 3 75 7.33E-25 T 22-04-2016 IPR009081 Phosphopantetheine binding ACP domain L21SP4_RS07130 77be6911b74ad97bb4bd1cc83afc202c 368 Pfam PF00483 Nucleotidyl transferase 14 292 7.0E-42 T 22-04-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Reactome: REACT_17015 L21SP4_RS07130 77be6911b74ad97bb4bd1cc83afc202c 368 SUPERFAMILY SSF53448 12 289 1.18E-58 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases L21SP4_RS07130 77be6911b74ad97bb4bd1cc83afc202c 368 PANTHER PTHR12526:SF387 162 303 5.9E-32 T 22-04-2016 L21SP4_RS07130 77be6911b74ad97bb4bd1cc83afc202c 368 Gene3D G3DSA:3.90.550.10 11 282 1.2E-73 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases L21SP4_RS07130 77be6911b74ad97bb4bd1cc83afc202c 368 SUPERFAMILY SSF159283 295 359 4.45E-16 T 22-04-2016 L21SP4_RS07130 77be6911b74ad97bb4bd1cc83afc202c 368 PANTHER PTHR12526 162 303 5.9E-32 T 22-04-2016 L21SP4_RS02545 2a33d95c1f072261eed2ff1c83f0dfbf 302 Gene3D G3DSA:3.40.50.620 1 134 8.7E-15 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP4_RS02545 2a33d95c1f072261eed2ff1c83f0dfbf 302 SUPERFAMILY SSF52402 4 139 1.0E-14 T 22-04-2016 L21SP4_RS02545 2a33d95c1f072261eed2ff1c83f0dfbf 302 Pfam PF00582 Universal stress protein family 145 284 3.7E-15 T 22-04-2016 IPR006016 UspA GO:0006950 L21SP4_RS02545 2a33d95c1f072261eed2ff1c83f0dfbf 302 Pfam PF00582 Universal stress protein family 4 137 1.2E-12 T 22-04-2016 IPR006016 UspA GO:0006950 L21SP4_RS02545 2a33d95c1f072261eed2ff1c83f0dfbf 302 SUPERFAMILY SSF52402 145 286 1.26E-18 T 22-04-2016 L21SP4_RS02545 2a33d95c1f072261eed2ff1c83f0dfbf 302 Gene3D G3DSA:3.40.50.620 135 286 4.5E-24 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP4_RS02620 8fdbc71d06a2cd9771c5830d6d8bf1c1 991 PANTHER PTHR33307 172 659 2.8E-189 T 22-04-2016 L21SP4_RS02620 8fdbc71d06a2cd9771c5830d6d8bf1c1 991 PANTHER PTHR33307 12 121 2.8E-189 T 22-04-2016 L21SP4_RS02620 8fdbc71d06a2cd9771c5830d6d8bf1c1 991 PANTHER PTHR33307 688 947 2.8E-189 T 22-04-2016 L21SP4_RS02620 8fdbc71d06a2cd9771c5830d6d8bf1c1 991 Pfam PF08531 Alpha-L-rhamnosidase N-terminal domain 192 365 8.0E-51 T 22-04-2016 IPR013737 Bacterial alpha-L-rhamnosidase N-terminal L21SP4_RS02620 8fdbc71d06a2cd9771c5830d6d8bf1c1 991 SUPERFAMILY SSF49265 18 98 2.64E-6 T 22-04-2016 IPR003961 Fibronectin type III GO:0005515 L21SP4_RS02620 8fdbc71d06a2cd9771c5830d6d8bf1c1 991 Gene3D G3DSA:2.60.40.10 18 95 4.0E-5 T 22-04-2016 IPR013783 Immunoglobulin-like fold L21SP4_RS02620 8fdbc71d06a2cd9771c5830d6d8bf1c1 991 Gene3D G3DSA:2.60.120.260 366 480 5.2E-13 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS02620 8fdbc71d06a2cd9771c5830d6d8bf1c1 991 Pfam PF05592 Bacterial alpha-L-rhamnosidase 375 945 4.2E-112 T 22-04-2016 IPR008902 Bacterial alpha-L-rhamnosidase L21SP4_RS02620 8fdbc71d06a2cd9771c5830d6d8bf1c1 991 PANTHER PTHR33307:SF5 172 659 2.8E-189 T 22-04-2016 L21SP4_RS02620 8fdbc71d06a2cd9771c5830d6d8bf1c1 991 PANTHER PTHR33307:SF5 12 121 2.8E-189 T 22-04-2016 L21SP4_RS02620 8fdbc71d06a2cd9771c5830d6d8bf1c1 991 PANTHER PTHR33307:SF5 688 947 2.8E-189 T 22-04-2016 L21SP4_RS02620 8fdbc71d06a2cd9771c5830d6d8bf1c1 991 SUPERFAMILY SSF48208 687 952 7.29E-33 T 22-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP4_RS02620 8fdbc71d06a2cd9771c5830d6d8bf1c1 991 SUPERFAMILY SSF48208 483 659 7.29E-33 T 22-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP4_RS02620 8fdbc71d06a2cd9771c5830d6d8bf1c1 991 PIRSF PIRSF010631 1 989 1.6E-216 T 22-04-2016 IPR016007 Alpha-L-rhamnosidase L21SP4_RS09205 1ec5f041e99a7ed14c0c654936ff2fb3 229 PANTHER PTHR24220:SF86 5 225 8.2E-93 T 22-04-2016 L21SP4_RS09205 1ec5f041e99a7ed14c0c654936ff2fb3 229 SMART SM00382 32 220 8.0E-14 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS09205 1ec5f041e99a7ed14c0c654936ff2fb3 229 SUPERFAMILY SSF52540 3 225 3.88E-69 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS09205 1ec5f041e99a7ed14c0c654936ff2fb3 229 Pfam PF00005 ABC transporter 24 172 8.9E-31 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 L21SP4_RS09205 1ec5f041e99a7ed14c0c654936ff2fb3 229 PANTHER PTHR24220 5 225 8.2E-93 T 22-04-2016 L21SP4_RS09205 1ec5f041e99a7ed14c0c654936ff2fb3 229 Gene3D G3DSA:3.40.50.300 2 225 7.2E-68 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS09205 1ec5f041e99a7ed14c0c654936ff2fb3 229 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 L21SP4_RS11945 566d7cbd22af98557af00a0de1b2e7f1 260 PANTHER PTHR21294 1 260 5.4E-115 T 22-04-2016 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 L21SP4_RS11945 566d7cbd22af98557af00a0de1b2e7f1 260 PIRSF PIRSF000090 1 260 2.5E-92 T 22-04-2016 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 L21SP4_RS11945 566d7cbd22af98557af00a0de1b2e7f1 260 SMART SM00893 22 212 9.0E-61 T 22-04-2016 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: REACT_6305 L21SP4_RS11945 566d7cbd22af98557af00a0de1b2e7f1 260 SUPERFAMILY SSF52402 1 256 3.07E-81 T 22-04-2016 L21SP4_RS11945 566d7cbd22af98557af00a0de1b2e7f1 260 Gene3D G3DSA:3.40.50.620 1 259 1.4E-96 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP4_RS11945 566d7cbd22af98557af00a0de1b2e7f1 260 PANTHER PTHR21294:SF0 1 260 5.4E-115 T 22-04-2016 L21SP4_RS11945 566d7cbd22af98557af00a0de1b2e7f1 260 Pfam PF01012 Electron transfer flavoprotein domain 24 207 2.7E-49 T 22-04-2016 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: REACT_6305 L21SP4_RS04665 c2f501b123ed1c0ae0e73704c9b74a7f 322 PANTHER PTHR30473:SF1 5 322 1.2E-133 T 22-04-2016 L21SP4_RS04665 c2f501b123ed1c0ae0e73704c9b74a7f 322 SUPERFAMILY SSF52540 108 275 1.68E-34 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS04665 c2f501b123ed1c0ae0e73704c9b74a7f 322 Gene3D G3DSA:3.40.50.300 108 311 4.6E-81 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS04665 c2f501b123ed1c0ae0e73704c9b74a7f 322 Pfam PF02562 PhoH-like protein 109 311 1.7E-87 T 22-04-2016 IPR003714 PhoH-like protein GO:0005524 L21SP4_RS04665 c2f501b123ed1c0ae0e73704c9b74a7f 322 PANTHER PTHR30473 5 322 1.2E-133 T 22-04-2016 L21SP4_RS08895 ca38c54011daa471ce944c69c48cd53a 488 SMART SM00880 215 474 3.6E-33 T 22-04-2016 IPR007899 CHAD domain L21SP4_RS08895 ca38c54011daa471ce944c69c48cd53a 488 Pfam PF01966 HD domain 19 134 2.7E-9 T 22-04-2016 IPR006674 HD domain L21SP4_RS08895 ca38c54011daa471ce944c69c48cd53a 488 SUPERFAMILY SSF109604 6 186 4.0E-27 T 22-04-2016 L21SP4_RS08895 ca38c54011daa471ce944c69c48cd53a 488 Pfam PF05235 CHAD domain 219 443 7.6E-40 T 22-04-2016 IPR007899 CHAD domain L21SP4_RS08895 ca38c54011daa471ce944c69c48cd53a 488 PANTHER PTHR39339 211 475 3.7E-19 T 22-04-2016 L21SP4_RS08895 ca38c54011daa471ce944c69c48cd53a 488 PANTHER PTHR39339:SF1 211 475 3.7E-19 T 22-04-2016 L21SP4_RS08895 ca38c54011daa471ce944c69c48cd53a 488 Gene3D G3DSA:1.10.3210.10 16 138 2.3E-9 T 22-04-2016 IPR006674 HD domain L21SP4_RS07680 a9ccf66c0fd9071f4f01a781b4f158ee 383 Pfam PF02687 FtsX-like permease family 261 368 2.8E-6 T 22-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 L21SP4_RS07680 a9ccf66c0fd9071f4f01a781b4f158ee 383 Pfam PF12704 MacB-like periplasmic core domain 22 217 4.1E-12 T 22-04-2016 IPR025857 MacB-like periplasmic core domain L21SP4_RS07680 a9ccf66c0fd9071f4f01a781b4f158ee 383 PANTHER PTHR30572 22 382 3.7E-17 T 22-04-2016 L21SP4_RS11055 8428d762f19de942004bfa146932a680 314 TIGRFAM TIGR00706 SppA_dom: signal peptide peptidase SppA, 36K type 54 267 5.7E-55 T 22-04-2016 IPR004635 Peptidase S49, SppA GO:0006508|GO:0008233 L21SP4_RS11055 8428d762f19de942004bfa146932a680 314 SUPERFAMILY SSF52096 49 170 6.14E-39 T 22-04-2016 IPR029045 ClpP/crotonase-like domain L21SP4_RS11055 8428d762f19de942004bfa146932a680 314 SUPERFAMILY SSF52096 199 257 6.14E-39 T 22-04-2016 IPR029045 ClpP/crotonase-like domain L21SP4_RS11055 8428d762f19de942004bfa146932a680 314 Pfam PF01343 Peptidase family S49 126 267 8.7E-37 T 22-04-2016 IPR002142 Peptidase S49 GO:0006508|GO:0008233 L21SP4_RS11055 8428d762f19de942004bfa146932a680 314 Gene3D G3DSA:3.90.226.10 200 273 1.8E-42 T 22-04-2016 IPR029045 ClpP/crotonase-like domain L21SP4_RS11055 8428d762f19de942004bfa146932a680 314 Gene3D G3DSA:3.90.226.10 50 162 1.8E-42 T 22-04-2016 IPR029045 ClpP/crotonase-like domain L21SP4_RS11055 8428d762f19de942004bfa146932a680 314 PANTHER PTHR33209 39 314 6.6E-66 T 22-04-2016 L21SP4_RS01440 ba90a75bd5459dc478aa418e2f7e4922 254 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 L21SP4_RS01440 ba90a75bd5459dc478aa418e2f7e4922 254 PANTHER PTHR24220 9 252 1.0E-132 T 22-04-2016 L21SP4_RS01440 ba90a75bd5459dc478aa418e2f7e4922 254 Gene3D G3DSA:3.40.50.300 7 248 1.4E-68 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS01440 ba90a75bd5459dc478aa418e2f7e4922 254 SMART SM00382 32 241 7.6E-14 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS01440 ba90a75bd5459dc478aa418e2f7e4922 254 PANTHER PTHR24220:SF585 9 252 1.0E-132 T 22-04-2016 L21SP4_RS01440 ba90a75bd5459dc478aa418e2f7e4922 254 Pfam PF00005 ABC transporter 24 179 2.7E-33 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 L21SP4_RS01440 ba90a75bd5459dc478aa418e2f7e4922 254 SUPERFAMILY SSF52540 6 241 3.55E-58 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS01440 ba90a75bd5459dc478aa418e2f7e4922 254 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 8 254 1.5E-120 T 22-04-2016 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 L21SP4_RS00445 66b4a7a3a26b472d441147d257799c83 347 Gene3D G3DSA:3.30.230.20 45 171 6.6E-12 T 22-04-2016 IPR015870 UDP-3-O-acyl N-acetylglucosamine deacetylase, N-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00359 L21SP4_RS00445 66b4a7a3a26b472d441147d257799c83 347 PANTHER PTHR33694 47 333 1.0E-14 T 22-04-2016 L21SP4_RS00445 66b4a7a3a26b472d441147d257799c83 347 SUPERFAMILY SSF54211 45 171 5.16E-11 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold L21SP4_RS00445 66b4a7a3a26b472d441147d257799c83 347 Gene3D G3DSA:3.30.1700.10 174 333 3.5E-7 T 22-04-2016 IPR011334 UDP-3-O-acyl N-acetylglucosamine deacetylase, C-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00359 L21SP4_RS00445 66b4a7a3a26b472d441147d257799c83 347 Pfam PF03331 UDP-3-O-acyl N-acetylglycosamine deacetylase 45 332 2.3E-29 T 22-04-2016 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00359 L21SP4_RS09670 82d174aa8e11d04022a87821ea0cfe74 103 Gene3D G3DSA:3.90.580.10 52 86 1.4E-5 T 22-04-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 L21SP4_RS09670 82d174aa8e11d04022a87821ea0cfe74 103 SUPERFAMILY SSF57783 8 87 2.21E-7 T 22-04-2016 L21SP4_RS09805 7042598ea231b846d2febe9c0774ae6e 257 Pfam PF00881 Nitroreductase family 69 251 1.7E-27 T 22-04-2016 IPR029479 Nitroreductase L21SP4_RS09805 7042598ea231b846d2febe9c0774ae6e 257 PANTHER PTHR23026:SF61 63 254 1.4E-34 T 22-04-2016 L21SP4_RS09805 7042598ea231b846d2febe9c0774ae6e 257 Gene3D G3DSA:3.40.109.10 65 253 3.1E-30 T 22-04-2016 IPR000415 Nitroreductase-like GO:0016491 L21SP4_RS09805 7042598ea231b846d2febe9c0774ae6e 257 SUPERFAMILY SSF55469 66 253 1.2E-29 T 22-04-2016 IPR000415 Nitroreductase-like GO:0016491 L21SP4_RS09805 7042598ea231b846d2febe9c0774ae6e 257 TIGRFAM TIGR03605 antibiot_sagB: SagB-type dehydrogenase domain 84 251 5.2E-35 T 22-04-2016 IPR020051 SagB-type dehydrogenase domain L21SP4_RS09805 7042598ea231b846d2febe9c0774ae6e 257 PANTHER PTHR23026 63 254 1.4E-34 T 22-04-2016 L21SP4_RS03825 801fa59c961139151ea4d9a36483d671 252 Gene3D G3DSA:3.90.550.10 5 249 1.1E-70 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases L21SP4_RS03825 801fa59c961139151ea4d9a36483d671 252 PANTHER PTHR21485 3 251 7.3E-93 T 22-04-2016 L21SP4_RS03825 801fa59c961139151ea4d9a36483d671 252 Pfam PF02348 Cytidylyltransferase 5 219 3.2E-47 T 22-04-2016 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|UniPathway: UPA00030|UniPathway: UPA00358 L21SP4_RS03825 801fa59c961139151ea4d9a36483d671 252 PANTHER PTHR21485:SF4 3 251 7.3E-93 T 22-04-2016 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|UniPathway: UPA00030|UniPathway: UPA00358 L21SP4_RS03825 801fa59c961139151ea4d9a36483d671 252 Hamap MF_00057 3-deoxy-manno-octulosonate cytidylyltransferase [kdsB]. 2 248 36.758 T 22-04-2016 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|UniPathway: UPA00030|UniPathway: UPA00358 L21SP4_RS03825 801fa59c961139151ea4d9a36483d671 252 SUPERFAMILY SSF53448 5 250 7.21E-57 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases L21SP4_RS03825 801fa59c961139151ea4d9a36483d671 252 TIGRFAM TIGR00466 kdsB: 3-deoxy-D-manno-octulosonate cytidylyltransferase 7 241 1.5E-62 T 22-04-2016 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|UniPathway: UPA00030|UniPathway: UPA00358 L21SP4_RS04120 5ea69268f770df0a944ddb3eb4c83ee6 75 Gene3D G3DSA:4.10.1160.10 33 75 3.8E-15 T 22-04-2016 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS04120 5ea69268f770df0a944ddb3eb4c83ee6 75 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 69 5.1E-16 T 22-04-2016 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS04120 5ea69268f770df0a944ddb3eb4c83ee6 75 Pfam PF00830 Ribosomal L28 family 3 71 1.2E-15 T 22-04-2016 IPR026569 Ribosomal protein L28/L24 GO:0003735 L21SP4_RS04120 5ea69268f770df0a944ddb3eb4c83ee6 75 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 75 15.554 T 22-04-2016 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS04120 5ea69268f770df0a944ddb3eb4c83ee6 75 SUPERFAMILY SSF143800 1 74 6.28E-19 T 22-04-2016 L21SP4_RS04450 4a06c6cb05d78b21ecb0afdcf13f7f34 997 SUPERFAMILY SSF49785 823 992 1.7E-18 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS04450 4a06c6cb05d78b21ecb0afdcf13f7f34 997 Pfam PF17132 alpha-L-rhamnosidase 714 782 6.6E-8 T 22-04-2016 IPR033400 Alpha-L-rhamnosidase RhaM L21SP4_RS04450 4a06c6cb05d78b21ecb0afdcf13f7f34 997 Pfam PF17132 alpha-L-rhamnosidase 235 669 3.6E-42 T 22-04-2016 IPR033400 Alpha-L-rhamnosidase RhaM L21SP4_RS04450 4a06c6cb05d78b21ecb0afdcf13f7f34 997 Pfam PF17132 alpha-L-rhamnosidase 64 195 1.8E-19 T 22-04-2016 IPR033400 Alpha-L-rhamnosidase RhaM L21SP4_RS04450 4a06c6cb05d78b21ecb0afdcf13f7f34 997 PANTHER PTHR36848 9 676 9.5E-52 T 22-04-2016 L21SP4_RS04450 4a06c6cb05d78b21ecb0afdcf13f7f34 997 Gene3D G3DSA:2.60.120.260 824 931 9.0E-13 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS04450 4a06c6cb05d78b21ecb0afdcf13f7f34 997 Gene3D G3DSA:2.60.120.260 963 991 9.0E-13 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS06075 65eb80acc7b51fe3701fd55427310c78 246 PANTHER PTHR14859:SF0 1 243 3.3E-24 T 22-04-2016 L21SP4_RS06075 65eb80acc7b51fe3701fd55427310c78 246 Gene3D G3DSA:3.60.10.10 95 238 2.8E-11 T 22-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase L21SP4_RS06075 65eb80acc7b51fe3701fd55427310c78 246 PANTHER PTHR14859 1 243 3.3E-24 T 22-04-2016 IPR027317 PGAP2-interacting protein L21SP4_RS06075 65eb80acc7b51fe3701fd55427310c78 246 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 32 230 2.1E-16 T 22-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase L21SP4_RS06075 65eb80acc7b51fe3701fd55427310c78 246 SUPERFAMILY SSF56219 1 237 7.72E-30 T 22-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase L21SP4_RS07625 353675235a36def00c30519b8e9c4cdb 164 ProSitePatterns PS01318 TsaA-like domain signature. 82 93 - T 22-04-2016 IPR023368 Uncharacterised protein family UPF0066, conserved site L21SP4_RS07625 353675235a36def00c30519b8e9c4cdb 164 Pfam PF01980 Uncharacterised protein family UPF0066 22 134 9.7E-35 T 22-04-2016 IPR023370 TsaA-like domain L21SP4_RS07625 353675235a36def00c30519b8e9c4cdb 164 TIGRFAM TIGR00104 tRNA_TsaA: tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase TsaA 4 138 2.6E-38 T 22-04-2016 IPR023370 TsaA-like domain L21SP4_RS07625 353675235a36def00c30519b8e9c4cdb 164 Gene3D G3DSA:2.40.30.70 6 146 5.6E-49 T 22-04-2016 IPR023370 TsaA-like domain L21SP4_RS07625 353675235a36def00c30519b8e9c4cdb 164 PANTHER PTHR12818 3 158 2.9E-50 T 22-04-2016 L21SP4_RS07625 353675235a36def00c30519b8e9c4cdb 164 SUPERFAMILY SSF118196 4 146 2.09E-51 T 22-04-2016 IPR023370 TsaA-like domain L21SP4_RS09390 869cf9af326b88ba58afa4fb62898a63 559 Pfam PF00474 Sodium:solute symporter family 68 441 2.6E-25 T 22-04-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 L21SP4_RS09390 869cf9af326b88ba58afa4fb62898a63 559 PANTHER PTHR11819 6 493 4.5E-26 T 22-04-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 L21SP4_RS05425 0251a00d960871362e54f1b9196ec32c 252 Gene3D G3DSA:3.30.1150.10 146 249 6.6E-15 T 22-04-2016 L21SP4_RS05425 0251a00d960871362e54f1b9196ec32c 252 PANTHER PTHR33446 58 249 2.9E-17 T 22-04-2016 L21SP4_RS05425 0251a00d960871362e54f1b9196ec32c 252 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 172 248 1.2E-22 T 22-04-2016 IPR006260 TonB, C-terminal GO:0006810 L21SP4_RS05425 0251a00d960871362e54f1b9196ec32c 252 PANTHER PTHR33446:SF2 58 249 2.9E-17 T 22-04-2016 L21SP4_RS05425 0251a00d960871362e54f1b9196ec32c 252 SUPERFAMILY SSF74653 169 246 6.41E-23 T 22-04-2016 L21SP4_RS05425 0251a00d960871362e54f1b9196ec32c 252 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 172 248 1.4E-22 T 22-04-2016 IPR006260 TonB, C-terminal GO:0006810 L21SP4_RS03810 6c63b31d7ba2a1984fc58921b05d157d 444 Pfam PF07690 Major Facilitator Superfamily 45 399 2.0E-24 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 L21SP4_RS03810 6c63b31d7ba2a1984fc58921b05d157d 444 Gene3D G3DSA:1.20.1250.20 41 219 7.1E-14 T 22-04-2016 L21SP4_RS03810 6c63b31d7ba2a1984fc58921b05d157d 444 PANTHER PTHR11360 16 108 7.7E-34 T 22-04-2016 L21SP4_RS03810 6c63b31d7ba2a1984fc58921b05d157d 444 PANTHER PTHR11360 127 443 7.7E-34 T 22-04-2016 L21SP4_RS03810 6c63b31d7ba2a1984fc58921b05d157d 444 Gene3D G3DSA:1.20.1250.20 253 440 1.8E-18 T 22-04-2016 L21SP4_RS03810 6c63b31d7ba2a1984fc58921b05d157d 444 SUPERFAMILY SSF103473 11 440 1.31E-38 T 22-04-2016 IPR020846 Major facilitator superfamily domain L21SP4_RS03810 6c63b31d7ba2a1984fc58921b05d157d 444 PANTHER PTHR11360:SF135 16 108 7.7E-34 T 22-04-2016 L21SP4_RS03810 6c63b31d7ba2a1984fc58921b05d157d 444 PANTHER PTHR11360:SF135 127 443 7.7E-34 T 22-04-2016 L21SP4_RS08595 1ec0e8785a4364daee9812c910513c92 432 SUPERFAMILY SSF53335 34 254 1.17E-11 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS08595 1ec0e8785a4364daee9812c910513c92 432 Gene3D G3DSA:3.40.50.150 32 254 1.4E-9 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS10705 47b8cc69effcda6718a6c9e174b2c585 290 PANTHER PTHR10794:SF37 144 286 1.3E-17 T 22-04-2016 L21SP4_RS10705 47b8cc69effcda6718a6c9e174b2c585 290 PANTHER PTHR10794 144 286 1.3E-17 T 22-04-2016 L21SP4_RS10705 47b8cc69effcda6718a6c9e174b2c585 290 Pfam PF02517 CAAX protease self-immunity 194 280 9.3E-18 T 22-04-2016 IPR003675 CAAX amino terminal protease GO:0016020 L21SP4_RS11530 4995e9e63282af4721cd9ab3f286a8ef 314 SMART SM00382 37 217 5.6E-11 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS11530 4995e9e63282af4721cd9ab3f286a8ef 314 Gene3D G3DSA:3.40.50.300 3 235 9.9E-70 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS11530 4995e9e63282af4721cd9ab3f286a8ef 314 PANTHER PTHR24220:SF160 8 233 2.8E-97 T 22-04-2016 L21SP4_RS11530 4995e9e63282af4721cd9ab3f286a8ef 314 Pfam PF00005 ABC transporter 29 170 1.4E-29 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 L21SP4_RS11530 4995e9e63282af4721cd9ab3f286a8ef 314 SUPERFAMILY SSF52540 22 233 1.0E-61 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS11530 4995e9e63282af4721cd9ab3f286a8ef 314 PANTHER PTHR24220 8 233 2.8E-97 T 22-04-2016 L21SP4_RS08980 9cb95ec4b803171f1e08ba25a4c7bb99 127 PANTHER PTHR10057 4 127 9.4E-33 T 22-04-2016 IPR004307 TspO/MBR-related protein GO:0016021 L21SP4_RS08980 9cb95ec4b803171f1e08ba25a4c7bb99 127 Pfam PF03073 TspO/MBR family 3 124 7.5E-38 T 22-04-2016 IPR004307 TspO/MBR-related protein GO:0016021 L21SP4_RS08980 9cb95ec4b803171f1e08ba25a4c7bb99 127 PIRSF PIRSF005859 1 127 9.7E-39 T 22-04-2016 IPR004307 TspO/MBR-related protein GO:0016021 L21SP4_RS03520 da3d689e5bf13b60b572f23c8550e9fd 244 PANTHER PTHR30269:SF24 5 244 3.0E-43 T 22-04-2016 L21SP4_RS03520 da3d689e5bf13b60b572f23c8550e9fd 244 Pfam PF01925 Sulfite exporter TauE/SafE 14 241 4.5E-25 T 22-04-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 L21SP4_RS03520 da3d689e5bf13b60b572f23c8550e9fd 244 PANTHER PTHR30269 5 244 3.0E-43 T 22-04-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 L21SP4_RS06420 a6ab48e4cbfae7df3607b12f3c7f3bab 914 Pfam PF13597 Anaerobic ribonucleoside-triphosphate reductase 237 882 1.9E-113 T 22-04-2016 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.17.4.2|KEGG: 00240+1.17.4.2|MetaCyc: PWY-7187|MetaCyc: PWY-7220|MetaCyc: PWY-7222 L21SP4_RS06420 a6ab48e4cbfae7df3607b12f3c7f3bab 914 Gene3D G3DSA:3.20.70.20 244 394 8.6E-112 T 22-04-2016 L21SP4_RS06420 a6ab48e4cbfae7df3607b12f3c7f3bab 914 Gene3D G3DSA:3.20.70.20 486 867 8.6E-112 T 22-04-2016 L21SP4_RS06420 a6ab48e4cbfae7df3607b12f3c7f3bab 914 SUPERFAMILY SSF51998 246 415 6.41E-27 T 22-04-2016 L21SP4_RS06420 a6ab48e4cbfae7df3607b12f3c7f3bab 914 Pfam PF03477 ATP cone domain 15 116 3.9E-8 T 22-04-2016 IPR005144 ATP-cone domain L21SP4_RS06420 a6ab48e4cbfae7df3607b12f3c7f3bab 914 PANTHER PTHR21075 133 891 1.8E-93 T 22-04-2016 L21SP4_RS06420 a6ab48e4cbfae7df3607b12f3c7f3bab 914 SUPERFAMILY SSF51998 484 868 1.01E-67 T 22-04-2016 L21SP4_RS07305 23821928ef47aa9fe3f4c25167ebdf8a 311 SUPERFAMILY SSF54523 18 59 3.85E-5 T 22-04-2016 L21SP4_RS07305 23821928ef47aa9fe3f4c25167ebdf8a 311 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 16 37 6.1E-5 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site L21SP4_RS10900 9aeade0479e032e1e10908e55f1debb9 783 PANTHER PTHR30332 428 764 2.6E-42 T 22-04-2016 L21SP4_RS10900 9aeade0479e032e1e10908e55f1debb9 783 Pfam PF00263 Bacterial type II and III secretion system protein 571 761 1.2E-35 T 22-04-2016 IPR004846 Type II/III secretion system GO:0009306 L21SP4_RS10900 9aeade0479e032e1e10908e55f1debb9 783 Gene3D G3DSA:1.25.40.10 126 166 3.7E-4 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS10900 9aeade0479e032e1e10908e55f1debb9 783 PRINTS PR00811 Bacterial general secretion pathway protein D signature 749 763 1.5E-9 T 22-04-2016 IPR001775 GspD/PilQ family L21SP4_RS10900 9aeade0479e032e1e10908e55f1debb9 783 PRINTS PR00811 Bacterial general secretion pathway protein D signature 726 744 1.5E-9 T 22-04-2016 IPR001775 GspD/PilQ family L21SP4_RS10900 9aeade0479e032e1e10908e55f1debb9 783 PRINTS PR00811 Bacterial general secretion pathway protein D signature 463 473 1.5E-9 T 22-04-2016 IPR001775 GspD/PilQ family L21SP4_RS04925 e402d20698073e9f08c17754d426a169 528 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 27 452 6.9E-144 T 22-04-2016 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 L21SP4_RS04925 e402d20698073e9f08c17754d426a169 528 SUPERFAMILY SSF50249 53 153 1.96E-13 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold L21SP4_RS04925 e402d20698073e9f08c17754d426a169 528 Gene3D G3DSA:2.40.50.140 44 153 1.6E-23 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold L21SP4_RS04925 e402d20698073e9f08c17754d426a169 528 SMART SM00316 51 147 0.0014 T 22-04-2016 IPR022967 RNA-binding domain, S1 L21SP4_RS04925 e402d20698073e9f08c17754d426a169 528 Pfam PF10150 Ribonuclease E/G family 149 419 3.9E-98 T 22-04-2016 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 L21SP4_RS04925 e402d20698073e9f08c17754d426a169 528 PANTHER PTHR30001 9 527 8.2E-168 T 22-04-2016 L21SP4_RS12025 5e5bc1992321ea630fa36a1520ac440e 847 SUPERFAMILY SSF48208 377 816 1.51E-27 T 22-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP4_RS12025 5e5bc1992321ea630fa36a1520ac440e 847 SUPERFAMILY SSF49785 10 101 2.43E-6 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS12025 5e5bc1992321ea630fa36a1520ac440e 847 Pfam PF05592 Bacterial alpha-L-rhamnosidase 266 635 5.2E-28 T 22-04-2016 IPR008902 Bacterial alpha-L-rhamnosidase L21SP4_RS12025 5e5bc1992321ea630fa36a1520ac440e 847 PANTHER PTHR33307 609 847 5.4E-13 T 22-04-2016 L21SP4_RS12025 5e5bc1992321ea630fa36a1520ac440e 847 PANTHER PTHR33307 373 592 5.4E-13 T 22-04-2016 L21SP4_RS12025 5e5bc1992321ea630fa36a1520ac440e 847 Gene3D G3DSA:2.60.120.260 7 116 3.5E-6 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS11545 e383d270679447cb4fb9bab0684552c4 476 Pfam PF13598 Domain of unknown function (DUF4139) 343 474 2.1E-7 T 22-04-2016 IPR011935 Conserved hypothetical protein CHP02231 L21SP4_RS11545 e383d270679447cb4fb9bab0684552c4 476 PANTHER PTHR38075 1 476 2.2E-33 T 22-04-2016 L21SP4_RS06515 bb1c490c2fc73ce76d2dd060377405cd 460 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 2 457 3.0E-111 T 22-04-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 L21SP4_RS06515 bb1c490c2fc73ce76d2dd060377405cd 460 PRINTS PR00171 Sugar transporter signature 99 118 4.35E-24 T 22-04-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 L21SP4_RS06515 bb1c490c2fc73ce76d2dd060377405cd 460 PRINTS PR00171 Sugar transporter signature 265 275 4.35E-24 T 22-04-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 L21SP4_RS06515 bb1c490c2fc73ce76d2dd060377405cd 460 PRINTS PR00171 Sugar transporter signature 16 26 4.35E-24 T 22-04-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 L21SP4_RS06515 bb1c490c2fc73ce76d2dd060377405cd 460 PRINTS PR00171 Sugar transporter signature 385 397 4.35E-24 T 22-04-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 L21SP4_RS06515 bb1c490c2fc73ce76d2dd060377405cd 460 PRINTS PR00171 Sugar transporter signature 362 383 4.35E-24 T 22-04-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 L21SP4_RS06515 bb1c490c2fc73ce76d2dd060377405cd 460 ProSitePatterns PS00216 Sugar transport proteins signature 1. 62 79 - T 22-04-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 L21SP4_RS06515 bb1c490c2fc73ce76d2dd060377405cd 460 ProSitePatterns PS00216 Sugar transport proteins signature 1. 309 326 - T 22-04-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 L21SP4_RS06515 bb1c490c2fc73ce76d2dd060377405cd 460 PANTHER PTHR23500:SF22 1 457 3.1E-191 T 22-04-2016 L21SP4_RS06515 bb1c490c2fc73ce76d2dd060377405cd 460 SUPERFAMILY SSF103473 11 207 8.63E-66 T 22-04-2016 IPR020846 Major facilitator superfamily domain L21SP4_RS06515 bb1c490c2fc73ce76d2dd060377405cd 460 SUPERFAMILY SSF103473 234 457 8.63E-66 T 22-04-2016 IPR020846 Major facilitator superfamily domain L21SP4_RS06515 bb1c490c2fc73ce76d2dd060377405cd 460 Gene3D G3DSA:1.20.1250.20 253 456 1.5E-20 T 22-04-2016 L21SP4_RS06515 bb1c490c2fc73ce76d2dd060377405cd 460 Gene3D G3DSA:1.20.1250.20 12 198 2.3E-22 T 22-04-2016 L21SP4_RS06515 bb1c490c2fc73ce76d2dd060377405cd 460 PANTHER PTHR23500 1 457 3.1E-191 T 22-04-2016 L21SP4_RS06515 bb1c490c2fc73ce76d2dd060377405cd 460 ProSitePatterns PS00217 Sugar transport proteins signature 2. 104 129 - T 22-04-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 L21SP4_RS06515 bb1c490c2fc73ce76d2dd060377405cd 460 Pfam PF00083 Sugar (and other) transporter 10 457 6.2E-112 T 22-04-2016 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 L21SP4_RS09890 1975806f6d64db3bd54b5d27bec39c7e 297 Pfam PF02219 Methylenetetrahydrofolate reductase 3 288 7.7E-93 T 22-04-2016 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00193 L21SP4_RS09890 1975806f6d64db3bd54b5d27bec39c7e 297 Gene3D G3DSA:3.20.20.220 2 291 3.2E-103 T 22-04-2016 IPR029041 FAD-linked oxidoreductase-like L21SP4_RS09890 1975806f6d64db3bd54b5d27bec39c7e 297 SUPERFAMILY SSF51730 1 289 1.71E-91 T 22-04-2016 IPR029041 FAD-linked oxidoreductase-like L21SP4_RS09890 1975806f6d64db3bd54b5d27bec39c7e 297 PANTHER PTHR21091:SF31 146 275 6.2E-34 T 22-04-2016 L21SP4_RS09890 1975806f6d64db3bd54b5d27bec39c7e 297 TIGRFAM TIGR00676 fadh2: methylenetetrahydrofolate reductase [NAD(P)H] 14 287 1.2E-99 T 22-04-2016 IPR004620 5,10-methylenetetrahydrofolate reductase GO:0004489|GO:0005829|GO:0009086|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00193 L21SP4_RS09890 1975806f6d64db3bd54b5d27bec39c7e 297 PANTHER PTHR21091 146 275 6.2E-34 T 22-04-2016 L21SP4_RS03775 b23acf59bca0dcfdd941a8a6221a57e9 88 Pfam PF01649 Ribosomal protein S20 2 83 8.4E-21 T 22-04-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS03775 b23acf59bca0dcfdd941a8a6221a57e9 88 PANTHER PTHR33398:SF1 1 86 3.5E-18 T 22-04-2016 L21SP4_RS03775 b23acf59bca0dcfdd941a8a6221a57e9 88 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 14.365 T 22-04-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS03775 b23acf59bca0dcfdd941a8a6221a57e9 88 PANTHER PTHR33398 1 86 3.5E-18 T 22-04-2016 L21SP4_RS03775 b23acf59bca0dcfdd941a8a6221a57e9 88 SUPERFAMILY SSF46992 3 85 3.92E-19 T 22-04-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS03775 b23acf59bca0dcfdd941a8a6221a57e9 88 Gene3D G3DSA:1.20.58.110 1 86 5.4E-22 T 22-04-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS03775 b23acf59bca0dcfdd941a8a6221a57e9 88 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 12 73 5.0E-4 T 22-04-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS03775 b23acf59bca0dcfdd941a8a6221a57e9 88 TIGRFAM TIGR00029 S20: ribosomal protein bS20 1 84 1.4E-17 T 22-04-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS00365 df395e630878b6966a1e0a4865576adc 342 Pfam PF01548 Transposase 12 156 7.8E-14 T 22-04-2016 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 L21SP4_RS00365 df395e630878b6966a1e0a4865576adc 342 PANTHER PTHR33055:SF3 7 336 3.4E-30 T 22-04-2016 L21SP4_RS00365 df395e630878b6966a1e0a4865576adc 342 PANTHER PTHR33055 7 336 3.4E-30 T 22-04-2016 L21SP4_RS00365 df395e630878b6966a1e0a4865576adc 342 Pfam PF02371 Transposase IS116/IS110/IS902 family 220 303 7.3E-12 T 22-04-2016 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 L21SP4_RS04380 f518e914abbc036303907dbdda6cb3a9 278 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 239 254 7.4E-6 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 L21SP4_RS04380 f518e914abbc036303907dbdda6cb3a9 278 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 254 270 7.4E-6 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 L21SP4_RS04380 f518e914abbc036303907dbdda6cb3a9 278 SUPERFAMILY SSF51182 13 88 2.83E-15 T 22-04-2016 IPR011051 RmlC-like cupin domain L21SP4_RS04380 f518e914abbc036303907dbdda6cb3a9 278 Pfam PF02311 AraC-like ligand binding domain 24 154 4.4E-15 T 22-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 L21SP4_RS04380 f518e914abbc036303907dbdda6cb3a9 278 SUPERFAMILY SSF46689 223 274 8.96E-15 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS04380 f518e914abbc036303907dbdda6cb3a9 278 PANTHER PTHR11019 10 278 1.2E-27 T 22-04-2016 L21SP4_RS04380 f518e914abbc036303907dbdda6cb3a9 278 Pfam PF12833 Helix-turn-helix domain 197 271 2.0E-21 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP4_RS04380 f518e914abbc036303907dbdda6cb3a9 278 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 224 266 - T 22-04-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 L21SP4_RS04380 f518e914abbc036303907dbdda6cb3a9 278 SMART SM00342 187 270 1.7E-23 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP4_RS04380 f518e914abbc036303907dbdda6cb3a9 278 Gene3D G3DSA:1.10.10.60 195 223 1.4E-4 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS04380 f518e914abbc036303907dbdda6cb3a9 278 Gene3D G3DSA:1.10.10.60 224 274 2.4E-20 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS04380 f518e914abbc036303907dbdda6cb3a9 278 Gene3D G3DSA:2.60.120.10 11 87 1.6E-16 T 22-04-2016 IPR014710 RmlC-like jelly roll fold L21SP4_RS09275 c8d217231844f582117422a21e7a9722 208 PANTHER PTHR34229 2 201 7.9E-41 T 22-04-2016 L21SP4_RS09275 c8d217231844f582117422a21e7a9722 208 Pfam PF01891 Cobalt uptake substrate-specific transmembrane region 2 197 2.3E-48 T 22-04-2016 IPR002751 Cobalamin (vitamin B12) biosynthesis CbiM family GO:0000041|GO:0016021 UniPathway: UPA00148 L21SP4_RS09275 c8d217231844f582117422a21e7a9722 208 PANTHER PTHR34229:SF1 2 201 7.9E-41 T 22-04-2016 L21SP4_RS08710 e66486cc216e89805ce6edaaf3fee5e5 208 SUPERFAMILY SSF63380 94 195 3.57E-30 T 22-04-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 L21SP4_RS08710 e66486cc216e89805ce6edaaf3fee5e5 208 Pfam PF00677 Lumazine binding domain 3 87 3.9E-20 T 22-04-2016 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 L21SP4_RS08710 e66486cc216e89805ce6edaaf3fee5e5 208 Pfam PF00677 Lumazine binding domain 100 184 6.0E-21 T 22-04-2016 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 L21SP4_RS08710 e66486cc216e89805ce6edaaf3fee5e5 208 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 195 6.8E-62 T 22-04-2016 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 L21SP4_RS08710 e66486cc216e89805ce6edaaf3fee5e5 208 Gene3D G3DSA:2.40.30.20 105 195 7.9E-28 T 22-04-2016 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 L21SP4_RS08710 e66486cc216e89805ce6edaaf3fee5e5 208 Gene3D G3DSA:2.40.30.20 5 104 3.4E-29 T 22-04-2016 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 L21SP4_RS08710 e66486cc216e89805ce6edaaf3fee5e5 208 PIRSF PIRSF000498 1 204 3.1E-68 T 22-04-2016 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 L21SP4_RS08710 e66486cc216e89805ce6edaaf3fee5e5 208 SUPERFAMILY SSF63380 1 88 1.79E-24 T 22-04-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 L21SP4_RS08710 e66486cc216e89805ce6edaaf3fee5e5 208 PANTHER PTHR21098 1 197 7.2E-77 T 22-04-2016 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 L21SP4_RS05325 4bb3e1012fcfcb4272535b611b44ddb7 150 Pfam PF02681 Divergent PAP2 family 8 140 4.4E-45 T 22-04-2016 IPR003832 Acid phosphatase/vanadium-dependent haloperoxidase-related L21SP4_RS05325 4bb3e1012fcfcb4272535b611b44ddb7 150 PANTHER PTHR31446:SF3 6 143 1.5E-53 T 22-04-2016 L21SP4_RS05325 4bb3e1012fcfcb4272535b611b44ddb7 150 PANTHER PTHR31446 6 143 1.5E-53 T 22-04-2016 L21SP4_RS09865 ac0b4104724936f13c718a8e07c6c32d 1012 SUPERFAMILY SSF52317 788 1011 4.35E-38 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like L21SP4_RS09865 ac0b4104724936f13c718a8e07c6c32d 1012 SUPERFAMILY SSF48371 25 194 7.76E-16 T 22-04-2016 IPR016024 Armadillo-type fold GO:0005488 L21SP4_RS09865 ac0b4104724936f13c718a8e07c6c32d 1012 SUPERFAMILY SSF48371 289 577 7.76E-16 T 22-04-2016 IPR016024 Armadillo-type fold GO:0005488 L21SP4_RS09865 ac0b4104724936f13c718a8e07c6c32d 1012 Gene3D G3DSA:1.25.10.10 23 216 3.0E-13 T 22-04-2016 IPR011989 Armadillo-like helical L21SP4_RS09865 ac0b4104724936f13c718a8e07c6c32d 1012 Gene3D G3DSA:1.25.10.10 279 440 1.3E-10 T 22-04-2016 IPR011989 Armadillo-like helical L21SP4_RS09865 ac0b4104724936f13c718a8e07c6c32d 1012 Gene3D G3DSA:1.25.10.10 478 610 1.3E-10 T 22-04-2016 IPR011989 Armadillo-like helical L21SP4_RS09865 ac0b4104724936f13c718a8e07c6c32d 1012 Gene3D G3DSA:3.40.50.880 786 1010 8.8E-38 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like L21SP4_RS09865 ac0b4104724936f13c718a8e07c6c32d 1012 Pfam PF06283 Trehalose utilisation 790 1006 1.3E-29 T 22-04-2016 IPR029010 ThuA-like domain L21SP4_RS09865 ac0b4104724936f13c718a8e07c6c32d 1012 Gene3D G3DSA:3.90.182.10 683 784 1.0E-5 T 22-04-2016 IPR011658 PA14 domain L21SP4_RS09965 1d0e20b507d760379ec8b35ef9191a86 1425 Gene3D G3DSA:3.20.20.80 143 363 2.5E-7 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP4_RS09965 1d0e20b507d760379ec8b35ef9191a86 1425 SUPERFAMILY SSF50939 874 981 5.1E-7 T 22-04-2016 IPR011040 Sialidases L21SP4_RS09965 1d0e20b507d760379ec8b35ef9191a86 1425 SUPERFAMILY SSF50939 1253 1400 5.1E-7 T 22-04-2016 IPR011040 Sialidases L21SP4_RS09965 1d0e20b507d760379ec8b35ef9191a86 1425 SUPERFAMILY SSF51445 127 358 3.65E-8 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily L21SP4_RS03815 7b585b0c3e3f7d803cb4bab4e9182c99 159 PANTHER PTHR11086:SF4 8 152 4.0E-59 T 22-04-2016 L21SP4_RS03815 7b585b0c3e3f7d803cb4bab4e9182c99 159 PIRSF PIRSF006019 1 159 1.6E-48 T 22-04-2016 IPR016473 Deoxycytidylate deaminase GO:0004132|GO:0006220|GO:0008270 KEGG: 00240+3.5.4.12|MetaCyc: PWY-7210 L21SP4_RS03815 7b585b0c3e3f7d803cb4bab4e9182c99 159 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 83 118 - T 22-04-2016 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 L21SP4_RS03815 7b585b0c3e3f7d803cb4bab4e9182c99 159 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 10 129 1.2E-24 T 22-04-2016 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 L21SP4_RS03815 7b585b0c3e3f7d803cb4bab4e9182c99 159 PANTHER PTHR11086 8 152 4.0E-59 T 22-04-2016 IPR015517 Deoxycytidylate deaminase-related L21SP4_RS03815 7b585b0c3e3f7d803cb4bab4e9182c99 159 Gene3D G3DSA:3.40.140.10 10 151 3.4E-37 T 22-04-2016 L21SP4_RS03815 7b585b0c3e3f7d803cb4bab4e9182c99 159 SUPERFAMILY SSF53927 12 151 8.86E-33 T 22-04-2016 IPR016193 Cytidine deaminase-like GO:0003824 L21SP4_RS09515 f4393d80a474b33089ea7aad91c8bcc3 561 Pfam PF10082 Putative beta-barrel porin 2 206 560 5.4E-14 T 22-04-2016 IPR018759 Putative beta-barrel porin 2 L21SP4_RS09515 f4393d80a474b33089ea7aad91c8bcc3 561 SUPERFAMILY SSF56935 346 377 5.95E-7 T 22-04-2016 L21SP4_RS09515 f4393d80a474b33089ea7aad91c8bcc3 561 SUPERFAMILY SSF56935 419 549 5.95E-7 T 22-04-2016 L21SP4_RS09515 f4393d80a474b33089ea7aad91c8bcc3 561 Gene3D G3DSA:2.40.160.10 308 472 5.8E-4 T 22-04-2016 IPR023614 Porin domain L21SP4_RS10565 af5e371c4ec5c363c7b74a769fd1a2a8 277 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 107 265 1.3E-24 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 L21SP4_RS10565 af5e371c4ec5c363c7b74a769fd1a2a8 277 PANTHER PTHR30177 5 272 2.0E-124 T 22-04-2016 L21SP4_RS10565 af5e371c4ec5c363c7b74a769fd1a2a8 277 PANTHER PTHR30177:SF2 5 272 2.0E-124 T 22-04-2016 L21SP4_RS10565 af5e371c4ec5c363c7b74a769fd1a2a8 277 SUPERFAMILY SSF161098 85 267 7.06E-40 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 L21SP4_RS10565 af5e371c4ec5c363c7b74a769fd1a2a8 277 Gene3D G3DSA:1.10.3720.10 84 264 1.6E-40 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 L21SP4_RS02095 bcfa2ec796a60f49b54153b28b60758c 307 PANTHER PTHR34106 6 302 5.7E-74 T 22-04-2016 L21SP4_RS02095 bcfa2ec796a60f49b54153b28b60758c 307 Gene3D G3DSA:2.115.10.20 4 305 5.1E-99 T 22-04-2016 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP4_RS02095 bcfa2ec796a60f49b54153b28b60758c 307 PANTHER PTHR34106:SF2 6 302 5.7E-74 T 22-04-2016 L21SP4_RS02095 bcfa2ec796a60f49b54153b28b60758c 307 Pfam PF04041 beta-1,4-mannooligosaccharide phosphorylase 24 305 2.4E-53 T 22-04-2016 IPR007184 Mannoside phosphorylase L21SP4_RS02095 bcfa2ec796a60f49b54153b28b60758c 307 PIRSF PIRSF016202 1 307 9.0E-93 T 22-04-2016 IPR007184 Mannoside phosphorylase L21SP4_RS02095 bcfa2ec796a60f49b54153b28b60758c 307 SUPERFAMILY SSF75005 4 297 5.82E-75 T 22-04-2016 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP4_RS09320 b1ef9d8677cc3b3b0af81e3e986d83b8 86 SUPERFAMILY SSF89447 3 43 1.06E-7 T 22-04-2016 L21SP4_RS09320 b1ef9d8677cc3b3b0af81e3e986d83b8 86 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 6 43 3.6E-8 T 22-04-2016 IPR007159 SpoVT-AbrB domain GO:0003677 L21SP4_RS09320 b1ef9d8677cc3b3b0af81e3e986d83b8 86 Gene3D G3DSA:2.10.260.10 5 42 1.4E-8 T 22-04-2016 L21SP4_RS09320 b1ef9d8677cc3b3b0af81e3e986d83b8 86 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 6 45 2.2E-6 T 22-04-2016 IPR007159 SpoVT-AbrB domain GO:0003677 L21SP4_RS09320 b1ef9d8677cc3b3b0af81e3e986d83b8 86 SMART SM00966 3 48 4.7E-6 T 22-04-2016 IPR007159 SpoVT-AbrB domain GO:0003677 L21SP4_RS05600 e69eed7b4b1ac9b9c2b90766348f4a7d 872 SUPERFAMILY SSF56059 615 669 6.59E-33 T 22-04-2016 L21SP4_RS05600 e69eed7b4b1ac9b9c2b90766348f4a7d 872 SUPERFAMILY SSF56059 294 535 6.59E-33 T 22-04-2016 L21SP4_RS05600 e69eed7b4b1ac9b9c2b90766348f4a7d 872 Gene3D G3DSA:3.30.470.20 485 670 1.2E-11 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 L21SP4_RS05600 e69eed7b4b1ac9b9c2b90766348f4a7d 872 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 299 669 1.5E-48 T 22-04-2016 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 L21SP4_RS05600 e69eed7b4b1ac9b9c2b90766348f4a7d 872 Gene3D G3DSA:3.30.1490.20 293 475 3.1E-31 T 22-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 L21SP4_RS03790 2d047952c47fc6aad4feaab0f7dca456 475 ProSitePatterns PS00149 Sulfatases signature 2. 135 145 - T 22-04-2016 IPR024607 Sulfatase, conserved site L21SP4_RS03790 2d047952c47fc6aad4feaab0f7dca456 475 PANTHER PTHR10342 6 459 5.0E-153 T 22-04-2016 L21SP4_RS03790 2d047952c47fc6aad4feaab0f7dca456 475 Gene3D G3DSA:3.30.1120.10 372 445 1.0E-19 T 22-04-2016 L21SP4_RS03790 2d047952c47fc6aad4feaab0f7dca456 475 Gene3D G3DSA:3.40.720.10 35 369 1.9E-112 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS03790 2d047952c47fc6aad4feaab0f7dca456 475 PANTHER PTHR10342:SF199 6 459 5.0E-153 T 22-04-2016 L21SP4_RS03790 2d047952c47fc6aad4feaab0f7dca456 475 Pfam PF00884 Sulfatase 37 350 2.4E-77 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS03790 2d047952c47fc6aad4feaab0f7dca456 475 SUPERFAMILY SSF53649 36 436 2.22E-125 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS02315 f33a251c3d8c1bebeba4c2bccf80b6df 267 PANTHER PTHR30622 1 263 5.1E-74 T 22-04-2016 L21SP4_RS02315 f33a251c3d8c1bebeba4c2bccf80b6df 267 Pfam PF02673 Bacitracin resistance protein BacA 7 257 5.7E-61 T 22-04-2016 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 L21SP4_RS02315 f33a251c3d8c1bebeba4c2bccf80b6df 267 PANTHER PTHR30622:SF4 1 263 5.1E-74 T 22-04-2016 L21SP4_RS02315 f33a251c3d8c1bebeba4c2bccf80b6df 267 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 1 264 15.213 T 22-04-2016 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 L21SP4_RS06250 548fafc8e04d8f251bc2b36d40bbda47 196 PANTHER PTHR11671 88 193 8.8E-13 T 22-04-2016 IPR002699 ATPase, V1 complex, subunit D GO:0042626 L21SP4_RS06250 548fafc8e04d8f251bc2b36d40bbda47 196 Pfam PF01813 ATP synthase subunit D 10 191 5.7E-36 T 22-04-2016 IPR002699 ATPase, V1 complex, subunit D GO:0042626 L21SP4_RS06250 548fafc8e04d8f251bc2b36d40bbda47 196 TIGRFAM TIGR00309 V_ATPase_subD: V-type ATPase, D subunit 1 194 3.8E-39 T 22-04-2016 IPR002699 ATPase, V1 complex, subunit D GO:0042626 L21SP4_RS06250 548fafc8e04d8f251bc2b36d40bbda47 196 PANTHER PTHR11671:SF2 88 193 8.8E-13 T 22-04-2016 L21SP4_RS10320 8f6df0f7fd470a0f78f5e514df769acd 127 PANTHER PTHR26402 6 124 3.1E-32 T 22-04-2016 L21SP4_RS10320 8f6df0f7fd470a0f78f5e514df769acd 127 SUPERFAMILY SSF52172 6 125 4.41E-35 T 22-04-2016 IPR011006 CheY-like superfamily L21SP4_RS10320 8f6df0f7fd470a0f78f5e514df769acd 127 Gene3D G3DSA:3.40.50.2300 7 125 2.0E-33 T 22-04-2016 L21SP4_RS10320 8f6df0f7fd470a0f78f5e514df769acd 127 SMART SM00448 6 120 3.3E-28 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 L21SP4_RS10320 8f6df0f7fd470a0f78f5e514df769acd 127 Pfam PF00072 Response regulator receiver domain 8 120 2.2E-25 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 L21SP4_RS07505 1ae6a1e07a5e0b37cb03598c3e384dad 76 SUPERFAMILY SSF46955 7 54 1.21E-7 T 22-04-2016 IPR009061 Putative DNA-binding domain L21SP4_RS07505 1ae6a1e07a5e0b37cb03598c3e384dad 76 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 11 54 2.2E-13 T 22-04-2016 IPR010093 SinI-like, DNA-binding domain GO:0003677 L21SP4_RS07505 1ae6a1e07a5e0b37cb03598c3e384dad 76 Pfam PF12728 Helix-turn-helix domain 7 56 9.4E-12 T 22-04-2016 L21SP4_RS07505 1ae6a1e07a5e0b37cb03598c3e384dad 76 Gene3D G3DSA:1.10.10.10 8 55 2.7E-9 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS04055 5564603513a133a2f26ea0299ee3e4f9 274 Gene3D G3DSA:3.40.50.1010 8 158 1.6E-43 T 22-04-2016 IPR029060 PIN domain-like L21SP4_RS04055 5564603513a133a2f26ea0299ee3e4f9 274 Pfam PF01936 NYN domain 11 154 1.6E-34 T 22-04-2016 IPR021139 NYN domain, limkain-b1-type L21SP4_RS04055 5564603513a133a2f26ea0299ee3e4f9 274 PANTHER PTHR35811:SF1 1 269 7.4E-20 T 22-04-2016 L21SP4_RS04055 5564603513a133a2f26ea0299ee3e4f9 274 PANTHER PTHR35811 1 269 7.4E-20 T 22-04-2016 L21SP4_RS00835 20427a84081c57d965bedb86e793b1f4 658 SUPERFAMILY SSF48452 238 384 4.49E-16 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS00835 20427a84081c57d965bedb86e793b1f4 658 SMART SM00028 357 390 230.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS00835 20427a84081c57d965bedb86e793b1f4 658 SMART SM00028 542 576 53.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS00835 20427a84081c57d965bedb86e793b1f4 658 SMART SM00028 577 610 0.64 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS00835 20427a84081c57d965bedb86e793b1f4 658 SMART SM00028 323 356 31.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS00835 20427a84081c57d965bedb86e793b1f4 658 SMART SM00028 508 541 39.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS00835 20427a84081c57d965bedb86e793b1f4 658 SMART SM00028 107 140 380.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS00835 20427a84081c57d965bedb86e793b1f4 658 SMART SM00028 254 287 15.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS00835 20427a84081c57d965bedb86e793b1f4 658 SMART SM00028 73 106 6.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS00835 20427a84081c57d965bedb86e793b1f4 658 SMART SM00028 611 644 0.006 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS00835 20427a84081c57d965bedb86e793b1f4 658 SMART SM00028 141 174 10.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP4_RS00835 20427a84081c57d965bedb86e793b1f4 658 Pfam PF13432 Tetratricopeptide repeat 583 645 9.1E-11 T 22-04-2016 L21SP4_RS00835 20427a84081c57d965bedb86e793b1f4 658 Pfam PF13432 Tetratricopeptide repeat 86 141 1.1E-6 T 22-04-2016 L21SP4_RS00835 20427a84081c57d965bedb86e793b1f4 658 SUPERFAMILY SSF48452 463 646 2.66E-29 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS00835 20427a84081c57d965bedb86e793b1f4 658 Pfam PF13428 Tetratricopeptide repeat 511 550 6.0E-6 T 22-04-2016 L21SP4_RS00835 20427a84081c57d965bedb86e793b1f4 658 SUPERFAMILY SSF48452 76 205 1.19E-15 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS00835 20427a84081c57d965bedb86e793b1f4 658 Gene3D G3DSA:1.25.40.10 73 201 8.8E-19 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS00835 20427a84081c57d965bedb86e793b1f4 658 Gene3D G3DSA:1.25.40.10 460 648 4.4E-34 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS00835 20427a84081c57d965bedb86e793b1f4 658 Gene3D G3DSA:1.25.40.10 238 420 1.2E-17 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS00835 20427a84081c57d965bedb86e793b1f4 658 PANTHER PTHR23083 250 386 2.6E-51 T 22-04-2016 L21SP4_RS00835 20427a84081c57d965bedb86e793b1f4 658 PANTHER PTHR23083 73 204 2.6E-51 T 22-04-2016 L21SP4_RS00835 20427a84081c57d965bedb86e793b1f4 658 PANTHER PTHR23083 462 653 2.6E-51 T 22-04-2016 L21SP4_RS00900 a02e65603084443233d43a6816cb52f7 171 Gene3D G3DSA:1.10.260.40 3 68 3.5E-15 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 L21SP4_RS00900 a02e65603084443233d43a6816cb52f7 171 SUPERFAMILY SSF47413 2 67 3.55E-14 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 L21SP4_RS00900 a02e65603084443233d43a6816cb52f7 171 SMART SM00530 7 62 3.2E-10 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 L21SP4_RS00900 a02e65603084443233d43a6816cb52f7 171 Pfam PF01381 Helix-turn-helix 8 59 1.9E-10 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 L21SP4_RS01535 af878f5745e7a621b6ecc59d5c649c45 235 Pfam PF13419 Haloacid dehalogenase-like hydrolase 14 193 1.0E-23 T 22-04-2016 IPR023214 HAD-like domain L21SP4_RS01535 af878f5745e7a621b6ecc59d5c649c45 235 SUPERFAMILY SSF56784 12 218 3.93E-46 T 22-04-2016 IPR023214 HAD-like domain L21SP4_RS01535 af878f5745e7a621b6ecc59d5c649c45 235 Gene3D G3DSA:3.40.50.1000 82 217 3.7E-37 T 22-04-2016 IPR023214 HAD-like domain L21SP4_RS01535 af878f5745e7a621b6ecc59d5c649c45 235 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 69 193 1.0E-16 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 L21SP4_RS01535 af878f5745e7a621b6ecc59d5c649c45 235 PANTHER PTHR18901 12 216 1.3E-48 T 22-04-2016 L21SP4_RS01535 af878f5745e7a621b6ecc59d5c649c45 235 Gene3D G3DSA:1.10.150.240 23 81 4.1E-5 T 22-04-2016 IPR023198 Phosphoglycolate phosphatase, domain 2 L21SP4_RS08675 aa946adb841ea541f5c5f3ee8e6afaf0 540 SUPERFAMILY SSF52402 261 522 1.04E-72 T 22-04-2016 L21SP4_RS08675 aa946adb841ea541f5c5f3ee8e6afaf0 540 Pfam PF00795 Carbon-nitrogen hydrolase 2 241 2.1E-23 T 22-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 L21SP4_RS08675 aa946adb841ea541f5c5f3ee8e6afaf0 540 TIGRFAM TIGR00552 nadE: NAD+ synthetase 269 517 3.1E-57 T 22-04-2016 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|UniPathway: UPA00253 L21SP4_RS08675 aa946adb841ea541f5c5f3ee8e6afaf0 540 Gene3D G3DSA:3.60.110.10 1 242 9.5E-56 T 22-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 L21SP4_RS08675 aa946adb841ea541f5c5f3ee8e6afaf0 540 Pfam PF02540 NAD synthase 268 514 7.4E-69 T 22-04-2016 IPR022310 NAD/GMP synthase L21SP4_RS08675 aa946adb841ea541f5c5f3ee8e6afaf0 540 SUPERFAMILY SSF56317 1 242 1.27E-56 T 22-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 L21SP4_RS08675 aa946adb841ea541f5c5f3ee8e6afaf0 540 Gene3D G3DSA:3.40.50.620 261 521 3.3E-71 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP4_RS08675 aa946adb841ea541f5c5f3ee8e6afaf0 540 PANTHER PTHR23090 1 533 4.3E-137 T 22-04-2016 L21SP4_RS03830 18a41e7f830ac610f9c3d5582c8d6bb4 285 TIGRFAM TIGR01362 KDO8P_synth: 3-deoxy-8-phosphooctulonate synthase 26 280 1.7E-111 T 22-04-2016 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008152|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674|UniPathway: UPA00030|UniPathway: UPA00357 L21SP4_RS03830 18a41e7f830ac610f9c3d5582c8d6bb4 285 Pfam PF00793 DAHP synthetase I family 17 274 8.2E-66 T 22-04-2016 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674|UniPathway: UPA00030|UniPathway: UPA00357 L21SP4_RS03830 18a41e7f830ac610f9c3d5582c8d6bb4 285 PANTHER PTHR21057:SF2 12 280 5.1E-145 T 22-04-2016 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008152|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674|UniPathway: UPA00030|UniPathway: UPA00357 L21SP4_RS03830 18a41e7f830ac610f9c3d5582c8d6bb4 285 SUPERFAMILY SSF51569 12 281 5.77E-100 T 22-04-2016 L21SP4_RS03830 18a41e7f830ac610f9c3d5582c8d6bb4 285 PANTHER PTHR21057 12 280 5.1E-145 T 22-04-2016 L21SP4_RS03830 18a41e7f830ac610f9c3d5582c8d6bb4 285 Gene3D G3DSA:3.20.20.70 25 282 1.4E-106 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP4_RS03830 18a41e7f830ac610f9c3d5582c8d6bb4 285 Hamap MF_00056 2-dehydro-3-deoxyphosphooctonate aldolase [kdsA]. 21 284 48.087 T 22-04-2016 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008152|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674|UniPathway: UPA00030|UniPathway: UPA00357 L21SP4_RS07205 63743a75250ae1ab19110679f627142b 188 Gene3D G3DSA:2.60.120.260 17 108 8.7E-4 T 22-04-2016 IPR008979 Galactose-binding domain-like L21SP4_RS07510 9679a97e61e8a9103074c692f0464976 124 SUPERFAMILY SSF47413 4 79 3.66E-14 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 L21SP4_RS07510 9679a97e61e8a9103074c692f0464976 124 PANTHER PTHR10245 4 112 1.4E-13 T 22-04-2016 L21SP4_RS07510 9679a97e61e8a9103074c692f0464976 124 Gene3D G3DSA:1.10.260.40 11 113 5.9E-19 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 L21SP4_RS07510 9679a97e61e8a9103074c692f0464976 124 SMART SM00530 14 75 2.9E-14 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 L21SP4_RS07510 9679a97e61e8a9103074c692f0464976 124 Pfam PF13560 Helix-turn-helix domain 10 76 2.1E-10 T 22-04-2016 L21SP4_RS11635 fda01892be6937b1c9cc2011abce785a 635 PANTHER PTHR10342:SF237 1 225 7.8E-121 T 22-04-2016 L21SP4_RS11635 fda01892be6937b1c9cc2011abce785a 635 PANTHER PTHR10342:SF237 250 484 7.8E-121 T 22-04-2016 L21SP4_RS11635 fda01892be6937b1c9cc2011abce785a 635 Pfam PF16347 Domain of unknown function (DUF4976) 363 462 5.7E-12 T 22-04-2016 IPR032506 Domain of unknown function DUF4976 L21SP4_RS11635 fda01892be6937b1c9cc2011abce785a 635 Pfam PF00884 Sulfatase 26 361 6.5E-55 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS11635 fda01892be6937b1c9cc2011abce785a 635 SUPERFAMILY SSF53649 25 461 2.09E-110 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS11635 fda01892be6937b1c9cc2011abce785a 635 Gene3D G3DSA:3.30.1120.10 395 465 1.3E-11 T 22-04-2016 L21SP4_RS11635 fda01892be6937b1c9cc2011abce785a 635 PANTHER PTHR10342 1 225 7.8E-121 T 22-04-2016 L21SP4_RS11635 fda01892be6937b1c9cc2011abce785a 635 PANTHER PTHR10342 250 484 7.8E-121 T 22-04-2016 L21SP4_RS11635 fda01892be6937b1c9cc2011abce785a 635 Gene3D G3DSA:3.40.720.10 23 379 1.1E-91 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS01060 debcc35431292eb37933076ebc51fe5f 957 Pfam PF12951 Passenger-associated-transport-repeat 741 769 0.61 T 22-04-2016 IPR013425 Autotransporter-associated beta strand repeat L21SP4_RS01060 debcc35431292eb37933076ebc51fe5f 957 Pfam PF12951 Passenger-associated-transport-repeat 161 181 0.63 T 22-04-2016 IPR013425 Autotransporter-associated beta strand repeat L21SP4_RS01060 debcc35431292eb37933076ebc51fe5f 957 Pfam PF12951 Passenger-associated-transport-repeat 397 425 9.3E-10 T 22-04-2016 IPR013425 Autotransporter-associated beta strand repeat L21SP4_RS01060 debcc35431292eb37933076ebc51fe5f 957 Pfam PF12951 Passenger-associated-transport-repeat 531 545 0.59 T 22-04-2016 IPR013425 Autotransporter-associated beta strand repeat L21SP4_RS01060 debcc35431292eb37933076ebc51fe5f 957 Pfam PF12951 Passenger-associated-transport-repeat 651 680 0.14 T 22-04-2016 IPR013425 Autotransporter-associated beta strand repeat L21SP4_RS01060 debcc35431292eb37933076ebc51fe5f 957 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 396 427 1.8E-12 T 22-04-2016 IPR013425 Autotransporter-associated beta strand repeat L21SP4_RS01060 debcc35431292eb37933076ebc51fe5f 957 SUPERFAMILY SSF51126 550 866 3.45E-6 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor L21SP4_RS01060 debcc35431292eb37933076ebc51fe5f 957 Gene3D G3DSA:2.160.20.20 460 804 2.4E-8 T 22-04-2016 IPR012332 P22 tailspike C-terminal domain-like L21SP4_RS01060 debcc35431292eb37933076ebc51fe5f 957 Gene3D G3DSA:2.160.20.20 349 427 2.4E-8 T 22-04-2016 IPR012332 P22 tailspike C-terminal domain-like L21SP4_RS11220 5053fe88bd776be7be3a05e63a6b9749 429 SUPERFAMILY SSF56801 89 400 5.26E-15 T 22-04-2016 L21SP4_RS11220 5053fe88bd776be7be3a05e63a6b9749 429 PANTHER PTHR36932:SF2 35 370 4.2E-28 T 22-04-2016 L21SP4_RS11220 5053fe88bd776be7be3a05e63a6b9749 429 PANTHER PTHR36932 35 370 4.2E-28 T 22-04-2016 L21SP4_RS03950 2e6e7c0e2ca521225f091829429d0924 116 Pfam PF04134 Protein of unknown function, DUF393 4 110 3.2E-20 T 22-04-2016 IPR007263 Protein of unknown function DUF393 L21SP4_RS03950 2e6e7c0e2ca521225f091829429d0924 116 PANTHER PTHR34290 1 116 2.5E-18 T 22-04-2016 L21SP4_RS09340 a511f2fe026ddf1a57085330bd759b17 448 PANTHER PTHR30203 4 440 1.7E-39 T 22-04-2016 L21SP4_RS09340 a511f2fe026ddf1a57085330bd759b17 448 SUPERFAMILY SSF56954 10 419 1.96E-74 T 22-04-2016 L21SP4_RS09340 a511f2fe026ddf1a57085330bd759b17 448 Gene3D G3DSA:1.20.1600.10 26 419 3.3E-63 T 22-04-2016 L21SP4_RS09340 a511f2fe026ddf1a57085330bd759b17 448 Pfam PF02321 Outer membrane efflux protein 31 216 1.1E-29 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 L21SP4_RS09340 a511f2fe026ddf1a57085330bd759b17 448 Pfam PF02321 Outer membrane efflux protein 258 414 8.2E-28 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 L21SP4_RS01590 fb944fb7db73b6fad1916aac86f5b8c1 560 Gene3D G3DSA:2.160.20.10 2 329 7.7E-15 T 22-04-2016 IPR012334 Pectin lyase fold L21SP4_RS01590 fb944fb7db73b6fad1916aac86f5b8c1 560 SUPERFAMILY SSF51126 2 328 1.81E-19 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor L21SP4_RS12145 8eafce3d6eecb4d1e84f1748c4593b8c 383 Pfam PF14238 Domain of unknown function (DUF4340) 71 257 2.3E-19 T 22-04-2016 IPR025641 Domain of unknown function DUF4340 L21SP4_RS07265 21a99fa17daaf25f38f9090e2ce7f36d 500 PANTHER PTHR10342:SF207 281 492 1.7E-140 T 22-04-2016 L21SP4_RS07265 21a99fa17daaf25f38f9090e2ce7f36d 500 PANTHER PTHR10342:SF207 1 264 1.7E-140 T 22-04-2016 L21SP4_RS07265 21a99fa17daaf25f38f9090e2ce7f36d 500 Gene3D G3DSA:3.40.720.10 27 405 1.9E-98 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS07265 21a99fa17daaf25f38f9090e2ce7f36d 500 Gene3D G3DSA:3.30.1120.10 423 492 2.6E-9 T 22-04-2016 L21SP4_RS07265 21a99fa17daaf25f38f9090e2ce7f36d 500 PANTHER PTHR10342 281 492 1.7E-140 T 22-04-2016 L21SP4_RS07265 21a99fa17daaf25f38f9090e2ce7f36d 500 PANTHER PTHR10342 1 264 1.7E-140 T 22-04-2016 L21SP4_RS07265 21a99fa17daaf25f38f9090e2ce7f36d 500 SUPERFAMILY SSF53649 196 491 1.1E-115 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS07265 21a99fa17daaf25f38f9090e2ce7f36d 500 SUPERFAMILY SSF53649 28 163 1.1E-115 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS07265 21a99fa17daaf25f38f9090e2ce7f36d 500 ProSitePatterns PS00523 Sulfatases signature 1. 74 86 - T 22-04-2016 IPR024607 Sulfatase, conserved site L21SP4_RS07265 21a99fa17daaf25f38f9090e2ce7f36d 500 Pfam PF00884 Sulfatase 29 389 1.9E-51 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS00740 8957c2a0adf547fca1bdc9e614305c29 260 Pfam PF04333 MlaA lipoprotein 49 243 2.3E-70 T 22-04-2016 IPR007428 MlaA lipoprotein GO:0016020 L21SP4_RS00740 8957c2a0adf547fca1bdc9e614305c29 260 PRINTS PR01805 VacJ lipoprotein signature 118 135 3.8E-19 T 22-04-2016 IPR007428 MlaA lipoprotein GO:0016020 L21SP4_RS00740 8957c2a0adf547fca1bdc9e614305c29 260 PRINTS PR01805 VacJ lipoprotein signature 155 172 3.8E-19 T 22-04-2016 IPR007428 MlaA lipoprotein GO:0016020 L21SP4_RS00740 8957c2a0adf547fca1bdc9e614305c29 260 PRINTS PR01805 VacJ lipoprotein signature 50 63 3.8E-19 T 22-04-2016 IPR007428 MlaA lipoprotein GO:0016020 L21SP4_RS00740 8957c2a0adf547fca1bdc9e614305c29 260 PRINTS PR01805 VacJ lipoprotein signature 67 83 3.8E-19 T 22-04-2016 IPR007428 MlaA lipoprotein GO:0016020 L21SP4_RS00740 8957c2a0adf547fca1bdc9e614305c29 260 PANTHER PTHR30035 48 247 1.9E-43 T 22-04-2016 IPR007428 MlaA lipoprotein GO:0016020 L21SP4_RS09760 6368a1cba987800fbadde23720719c4e 162 Pfam PF13189 Cytidylate kinase-like family 2 139 1.6E-19 T 22-04-2016 IPR026865 Cytidylate kinase-like family MetaCyc: PWY-7205 L21SP4_RS09760 6368a1cba987800fbadde23720719c4e 162 Gene3D G3DSA:3.40.50.300 3 158 1.2E-27 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS07900 c52f05fae17eb3dc6fcd2978f3f71094 244 PANTHER PTHR12553 1 244 6.8E-32 T 22-04-2016 L21SP4_RS07900 c52f05fae17eb3dc6fcd2978f3f71094 244 Gene3D G3DSA:3.60.15.10 1 242 2.5E-38 T 22-04-2016 IPR001279 Metallo-beta-lactamase L21SP4_RS07900 c52f05fae17eb3dc6fcd2978f3f71094 244 SUPERFAMILY SSF56281 1 242 1.01E-39 T 22-04-2016 IPR001279 Metallo-beta-lactamase L21SP4_RS07900 c52f05fae17eb3dc6fcd2978f3f71094 244 Pfam PF12706 Beta-lactamase superfamily domain 46 211 4.8E-16 T 22-04-2016 IPR001279 Metallo-beta-lactamase L21SP4_RS07900 c52f05fae17eb3dc6fcd2978f3f71094 244 SMART SM00849 17 188 8.6E-5 T 22-04-2016 IPR001279 Metallo-beta-lactamase L21SP4_RS08290 686d63dba1d21095b9c73d7a18f4ef4e 37 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 37 17.534 T 22-04-2016 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS08290 686d63dba1d21095b9c73d7a18f4ef4e 37 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 36 - T 22-04-2016 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS08290 686d63dba1d21095b9c73d7a18f4ef4e 37 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 37 3.1E-21 T 22-04-2016 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS08290 686d63dba1d21095b9c73d7a18f4ef4e 37 SUPERFAMILY SSF57840 1 37 3.01E-16 T 22-04-2016 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS08290 686d63dba1d21095b9c73d7a18f4ef4e 37 PANTHER PTHR18804 1 37 3.8E-16 T 22-04-2016 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS08290 686d63dba1d21095b9c73d7a18f4ef4e 37 Pfam PF00444 Ribosomal protein L36 1 37 9.1E-20 T 22-04-2016 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP4_RS08175 4fa3c7eacfc9a790a779360cec0c4801 490 PANTHER PTHR35342:SF4 1 488 1.2E-157 T 22-04-2016 L21SP4_RS08175 4fa3c7eacfc9a790a779360cec0c4801 490 PANTHER PTHR35342 1 488 1.2E-157 T 22-04-2016 L21SP4_RS08175 4fa3c7eacfc9a790a779360cec0c4801 490 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 20 436 9.8E-133 T 22-04-2016 IPR002823 Protein of unknown function DUF112, transmembrane L21SP4_RS04540 83224ad1467eacedb9ffb1284fff19c0 345 Pfam PF06379 L-rhamnose-proton symport protein (RhaT) 5 339 1.9E-64 T 22-04-2016 IPR004673 L-rhamnose-proton symport, RhaT GO:0008645|GO:0015153|GO:0016021 L21SP4_RS06890 3c231815df291a7a457b7e96504208c9 244 Pfam PF02698 DUF218 domain 54 202 1.1E-7 T 22-04-2016 IPR003848 Domain of unknown function DUF218 L21SP4_RS10950 6951532b782dd8a9152b3da80032b5b1 212 SUPERFAMILY SSF74653 128 209 3.4E-24 T 22-04-2016 L21SP4_RS10950 6951532b782dd8a9152b3da80032b5b1 212 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 136 210 5.4E-20 T 22-04-2016 IPR006260 TonB, C-terminal GO:0006810 L21SP4_RS10950 6951532b782dd8a9152b3da80032b5b1 212 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 134 209 2.7E-23 T 22-04-2016 IPR006260 TonB, C-terminal GO:0006810 L21SP4_RS10950 6951532b782dd8a9152b3da80032b5b1 212 PANTHER PTHR33446 51 209 1.1E-21 T 22-04-2016 L21SP4_RS10950 6951532b782dd8a9152b3da80032b5b1 212 Gene3D G3DSA:3.30.1150.10 119 210 1.9E-14 T 22-04-2016 L21SP4_RS10950 6951532b782dd8a9152b3da80032b5b1 212 PRINTS PR01374 Gram-negative bacterial tonB protein signature 151 169 2.1E-8 T 22-04-2016 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 L21SP4_RS10950 6951532b782dd8a9152b3da80032b5b1 212 PRINTS PR01374 Gram-negative bacterial tonB protein signature 51 61 2.1E-8 T 22-04-2016 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 L21SP4_RS10950 6951532b782dd8a9152b3da80032b5b1 212 PRINTS PR01374 Gram-negative bacterial tonB protein signature 130 151 2.1E-8 T 22-04-2016 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 L21SP4_RS06590 7acb3e76c02ec6865c1cbf7096c3e2aa 175 Pfam PF13487 HD domain 11 58 5.0E-5 T 22-04-2016 L21SP4_RS09770 fc375d4dbb9cea93978cc0211d024adb 431 Pfam PF04986 Putative transposase 125 307 4.2E-23 T 22-04-2016 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 L21SP4_RS09770 fc375d4dbb9cea93978cc0211d024adb 431 Pfam PF14319 Transposase zinc-binding domain 5 98 3.8E-16 T 22-04-2016 IPR026889 Transposase zinc-binding domain L21SP4_RS04690 49ff14a7f4679417f648bfaf4f93387e 231 PANTHER PTHR39337 1 150 2.6E-26 T 22-04-2016 L21SP4_RS04690 49ff14a7f4679417f648bfaf4f93387e 231 Pfam PF04343 Protein of unknown function, DUF488 14 127 4.2E-25 T 22-04-2016 IPR007438 Protein of unknown function DUF488 L21SP4_RS04690 49ff14a7f4679417f648bfaf4f93387e 231 PANTHER PTHR39337:SF1 1 150 2.6E-26 T 22-04-2016 L21SP4_RS05195 a4564a67ec560f9a662e8e6650fbe610 162 SUPERFAMILY SSF54197 6 153 1.29E-34 T 22-04-2016 IPR011146 HIT-like domain GO:0003824 L21SP4_RS05195 a4564a67ec560f9a662e8e6650fbe610 162 PANTHER PTHR23089:SF16 1 161 1.4E-69 T 22-04-2016 L21SP4_RS05195 a4564a67ec560f9a662e8e6650fbe610 162 Pfam PF01230 HIT domain 38 129 4.9E-11 T 22-04-2016 IPR001310 Histidine triad (HIT) protein L21SP4_RS05195 a4564a67ec560f9a662e8e6650fbe610 162 PANTHER PTHR23089 1 161 1.4E-69 T 22-04-2016 IPR001310 Histidine triad (HIT) protein L21SP4_RS05195 a4564a67ec560f9a662e8e6650fbe610 162 Gene3D G3DSA:3.30.428.10 16 157 8.9E-32 T 22-04-2016 IPR011146 HIT-like domain GO:0003824 L21SP4_RS03215 75ba4b9fff528e06b1cf7a2def2a5c57 529 SUPERFAMILY SSF52540 28 115 3.96E-6 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS03215 75ba4b9fff528e06b1cf7a2def2a5c57 529 SUPERFAMILY SSF52540 152 257 3.96E-6 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS03215 75ba4b9fff528e06b1cf7a2def2a5c57 529 Gene3D G3DSA:3.40.50.300 27 170 2.8E-9 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS09510 8071da0d9ce96054bdeae3cc43614886 707 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 481 682 2.8E-50 T 22-04-2016 IPR005702 Exopolysaccharide synthesis protein GO:0045226 L21SP4_RS09510 8071da0d9ce96054bdeae3cc43614886 707 PANTHER PTHR32309 1 695 6.5E-124 T 22-04-2016 L21SP4_RS09510 8071da0d9ce96054bdeae3cc43614886 707 SUPERFAMILY SSF52540 502 688 3.29E-38 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS09510 8071da0d9ce96054bdeae3cc43614886 707 PANTHER PTHR32309:SF13 1 695 6.5E-124 T 22-04-2016 L21SP4_RS09510 8071da0d9ce96054bdeae3cc43614886 707 Gene3D G3DSA:3.40.50.300 503 676 1.9E-36 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS09510 8071da0d9ce96054bdeae3cc43614886 707 Pfam PF02706 Chain length determinant protein 20 165 4.6E-21 T 22-04-2016 IPR003856 Lipopolysaccharide biosynthesis GO:0009103|GO:0016020 L21SP4_RS09510 8071da0d9ce96054bdeae3cc43614886 707 Pfam PF13614 AAA domain 510 647 7.0E-17 T 22-04-2016 IPR025669 AAA domain L21SP4_RS10130 ce112c4b3380bb66be708ff85b1eca1c 217 Gene3D G3DSA:3.40.50.150 77 209 2.5E-11 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS10130 ce112c4b3380bb66be708ff85b1eca1c 217 SUPERFAMILY SSF53335 64 204 2.93E-18 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS10130 ce112c4b3380bb66be708ff85b1eca1c 217 Pfam PF13489 Methyltransferase domain 66 203 2.5E-22 T 22-04-2016 L21SP4_RS03170 b7775e150b9626c6cba566508280729c 357 Gene3D G3DSA:3.40.1190.20 4 351 1.2E-60 T 22-04-2016 IPR029056 Ribokinase-like L21SP4_RS03170 b7775e150b9626c6cba566508280729c 357 Pfam PF00294 pfkB family carbohydrate kinase 143 331 1.9E-15 T 22-04-2016 IPR011611 Carbohydrate kinase PfkB L21SP4_RS03170 b7775e150b9626c6cba566508280729c 357 PANTHER PTHR10584 17 348 2.2E-91 T 22-04-2016 L21SP4_RS03170 b7775e150b9626c6cba566508280729c 357 SUPERFAMILY SSF53613 9 345 6.86E-48 T 22-04-2016 IPR029056 Ribokinase-like L21SP4_RS03170 b7775e150b9626c6cba566508280729c 357 PANTHER PTHR10584:SF203 17 348 2.2E-91 T 22-04-2016 L21SP4_RS06475 164a402245118d0bcb9cba96955c6efb 327 Pfam PF01145 SPFH domain / Band 7 family 33 238 5.4E-22 T 22-04-2016 IPR001107 Band 7 domain L21SP4_RS06475 164a402245118d0bcb9cba96955c6efb 327 SMART SM00244 29 218 6.0E-20 T 22-04-2016 IPR001107 Band 7 domain L21SP4_RS06475 164a402245118d0bcb9cba96955c6efb 327 PIRSF PIRSF005651 5 326 6.7E-95 T 22-04-2016 IPR010200 HflC GO:0016021|GO:0052547 L21SP4_RS06475 164a402245118d0bcb9cba96955c6efb 327 TIGRFAM TIGR01932 hflC: HflC protein 15 321 4.0E-78 T 22-04-2016 IPR010200 HflC GO:0016021|GO:0052547 L21SP4_RS06475 164a402245118d0bcb9cba96955c6efb 327 PANTHER PTHR10264:SF80 179 323 3.1E-60 T 22-04-2016 L21SP4_RS06475 164a402245118d0bcb9cba96955c6efb 327 PANTHER PTHR10264:SF80 11 147 3.1E-60 T 22-04-2016 L21SP4_RS06475 164a402245118d0bcb9cba96955c6efb 327 SUPERFAMILY SSF117892 178 228 1.7E-17 T 22-04-2016 IPR001107 Band 7 domain L21SP4_RS06475 164a402245118d0bcb9cba96955c6efb 327 SUPERFAMILY SSF117892 63 146 1.7E-17 T 22-04-2016 IPR001107 Band 7 domain L21SP4_RS06475 164a402245118d0bcb9cba96955c6efb 327 PANTHER PTHR10264 179 323 3.1E-60 T 22-04-2016 IPR001972 Stomatin family GO:0016020 L21SP4_RS06475 164a402245118d0bcb9cba96955c6efb 327 PANTHER PTHR10264 11 147 3.1E-60 T 22-04-2016 IPR001972 Stomatin family GO:0016020 L21SP4_RS00450 5836cb77eaa3f064041bf7c9fc65d0c4 248 PANTHER PTHR10859 13 245 2.3E-60 T 22-04-2016 L21SP4_RS00450 5836cb77eaa3f064041bf7c9fc65d0c4 248 Gene3D G3DSA:3.90.550.10 13 236 2.0E-22 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases L21SP4_RS00450 5836cb77eaa3f064041bf7c9fc65d0c4 248 SUPERFAMILY SSF53448 13 227 1.22E-38 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases L21SP4_RS00450 5836cb77eaa3f064041bf7c9fc65d0c4 248 Pfam PF00535 Glycosyl transferase family 2 13 175 3.4E-24 T 22-04-2016 IPR001173 Glycosyltransferase 2-like L21SP4_RS02835 82487ae0572a4781523c0ef93e3eca90 351 SUPERFAMILY SSF143631 33 342 6.54E-92 T 22-04-2016 IPR003374 ApbE-like domain L21SP4_RS02835 82487ae0572a4781523c0ef93e3eca90 351 Pfam PF02424 ApbE family 39 319 9.1E-86 T 22-04-2016 IPR024932 Flavin transferase ApbE GO:0017013 L21SP4_RS02835 82487ae0572a4781523c0ef93e3eca90 351 PIRSF PIRSF006268 1 345 5.0E-85 T 22-04-2016 IPR024932 Flavin transferase ApbE GO:0017013 L21SP4_RS02835 82487ae0572a4781523c0ef93e3eca90 351 PANTHER PTHR30040 1 348 1.0E-106 T 22-04-2016 L21SP4_RS02835 82487ae0572a4781523c0ef93e3eca90 351 PANTHER PTHR30040:SF3 1 348 1.0E-106 T 22-04-2016 L21SP4_RS09525 3dc520a66df1dc08a67bbc0b637dcabe 305 SUPERFAMILY SSF53098 75 284 2.28E-31 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS09525 3dc520a66df1dc08a67bbc0b637dcabe 305 PANTHER PTHR10954:SF12 1 284 2.1E-41 T 22-04-2016 L21SP4_RS09525 3dc520a66df1dc08a67bbc0b637dcabe 305 TIGRFAM TIGR00716 rnhC: ribonuclease HIII 6 278 3.0E-63 T 22-04-2016 IPR004641 Ribonuclease HIII GO:0004523|GO:0005737|GO:0016070 L21SP4_RS09525 3dc520a66df1dc08a67bbc0b637dcabe 305 Gene3D G3DSA:3.30.420.10 75 231 1.6E-25 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS09525 3dc520a66df1dc08a67bbc0b637dcabe 305 Pfam PF01351 Ribonuclease HII 76 279 1.9E-24 T 22-04-2016 IPR024567 Ribonuclease HII/HIII domain L21SP4_RS09525 3dc520a66df1dc08a67bbc0b637dcabe 305 PANTHER PTHR10954 1 284 2.1E-41 T 22-04-2016 IPR001352 Ribonuclease HII/HIII GO:0003723|GO:0004523 L21SP4_RS09525 3dc520a66df1dc08a67bbc0b637dcabe 305 Pfam PF11858 Domain of unknown function (DUF3378) 10 45 1.9E-6 T 22-04-2016 IPR024568 Ribonuclease HIII, N-terminal L21SP4_RS09525 3dc520a66df1dc08a67bbc0b637dcabe 305 PIRSF PIRSF037748 4 287 9.0E-69 T 22-04-2016 IPR004641 Ribonuclease HIII GO:0004523|GO:0005737|GO:0016070 L21SP4_RS04585 58abca5c4c85c6915815a308e7d5c5c3 736 Gene3D G3DSA:2.60.420.10 658 705 2.3E-5 T 22-04-2016 L21SP4_RS04585 58abca5c4c85c6915815a308e7d5c5c3 736 SUPERFAMILY SSF48208 297 525 7.78E-24 T 22-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP4_RS04585 58abca5c4c85c6915815a308e7d5c5c3 736 SUPERFAMILY SSF48208 584 703 7.78E-24 T 22-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP4_RS04585 58abca5c4c85c6915815a308e7d5c5c3 736 Gene3D G3DSA:1.50.10.10 417 516 1.2E-4 T 22-04-2016 IPR012341 Six-hairpin glycosidase GO:0003824 L21SP4_RS09025 e0605224d4e9cb16f350d9c41544fc83 240 PANTHER PTHR36007 1 228 1.5E-44 T 22-04-2016 L21SP4_RS09025 e0605224d4e9cb16f350d9c41544fc83 240 Pfam PF06695 Putative small multi-drug export protein 60 191 5.0E-37 T 22-04-2016 IPR009577 Putative small multi-drug export L21SP4_RS00300 785db7aa598b2ca0f0689f9a49a43ac0 126 PANTHER PTHR30558:SF3 1 125 1.3E-25 T 22-04-2016 L21SP4_RS00300 785db7aa598b2ca0f0689f9a49a43ac0 126 Pfam PF02472 Biopolymer transport protein ExbD/TolR 2 118 4.6E-25 T 22-04-2016 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 L21SP4_RS00300 785db7aa598b2ca0f0689f9a49a43ac0 126 PANTHER PTHR30558 1 125 1.3E-25 T 22-04-2016 L21SP4_RS01400 6478f05e3b9859523240da497bdbe32e 221 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 35 52 1.3E-5 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site L21SP4_RS01400 6478f05e3b9859523240da497bdbe32e 221 SUPERFAMILY SSF54523 36 108 5.81E-9 T 22-04-2016 L21SP4_RS01400 6478f05e3b9859523240da497bdbe32e 221 Pfam PF07963 Prokaryotic N-terminal methylation motif 35 51 4.1E-5 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site L21SP4_RS03645 d1ef1509b75d2ae23bfd5e955f13a5e2 394 SUPERFAMILY SSF51445 113 207 1.74E-8 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily L21SP4_RS03645 d1ef1509b75d2ae23bfd5e955f13a5e2 394 SUPERFAMILY SSF51445 246 316 1.74E-8 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily L21SP4_RS03645 d1ef1509b75d2ae23bfd5e955f13a5e2 394 PANTHER PTHR30032:SF2 38 209 3.2E-25 T 22-04-2016 L21SP4_RS03645 d1ef1509b75d2ae23bfd5e955f13a5e2 394 PANTHER PTHR30032:SF2 226 326 3.2E-25 T 22-04-2016 L21SP4_RS03645 d1ef1509b75d2ae23bfd5e955f13a5e2 394 Pfam PF02638 Glycosyl hydrolase-like 10 45 323 2.1E-19 T 22-04-2016 IPR003790 Glycosyl hydrolase-like 10 L21SP4_RS03645 d1ef1509b75d2ae23bfd5e955f13a5e2 394 PANTHER PTHR30032 38 209 3.2E-25 T 22-04-2016 L21SP4_RS03645 d1ef1509b75d2ae23bfd5e955f13a5e2 394 PANTHER PTHR30032 226 326 3.2E-25 T 22-04-2016 L21SP4_RS00360 9c930c80b75a555cc22688274e033da9 481 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 72 322 1.6E-15 T 22-04-2016 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 L21SP4_RS00360 9c930c80b75a555cc22688274e033da9 481 Gene3D G3DSA:3.20.20.80 28 304 1.0E-29 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP4_RS00360 9c930c80b75a555cc22688274e033da9 481 SUPERFAMILY SSF51445 24 312 4.73E-29 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily L21SP4_RS05740 33f535f6aa073c5e55401639391ae1cd 431 PANTHER PTHR30217 1 413 3.4E-115 T 22-04-2016 L21SP4_RS05740 33f535f6aa073c5e55401639391ae1cd 431 PANTHER PTHR30217:SF6 1 413 3.4E-115 T 22-04-2016 L21SP4_RS05740 33f535f6aa073c5e55401639391ae1cd 431 ProSitePatterns PS01276 Peptidase family U32 signature. 173 191 - T 22-04-2016 IPR001539 Peptidase U32 GO:0006508|GO:0008233 KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- L21SP4_RS05740 33f535f6aa073c5e55401639391ae1cd 431 Pfam PF01136 Peptidase family U32 81 314 3.1E-70 T 22-04-2016 IPR001539 Peptidase U32 GO:0006508|GO:0008233 KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- L21SP4_RS01970 aa4299048a6f685823b0ee7c16cf6b62 138 PIRSF PIRSF004681 1 138 2.3E-37 T 22-04-2016 IPR001602 Uncharacterised protein family UPF0047 L21SP4_RS01970 aa4299048a6f685823b0ee7c16cf6b62 138 Pfam PF01894 Uncharacterised protein family UPF0047 20 135 6.1E-34 T 22-04-2016 IPR001602 Uncharacterised protein family UPF0047 L21SP4_RS01970 aa4299048a6f685823b0ee7c16cf6b62 138 PANTHER PTHR30615:SF2 1 138 1.4E-87 T 22-04-2016 L21SP4_RS01970 aa4299048a6f685823b0ee7c16cf6b62 138 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 7 138 1.7E-33 T 22-04-2016 IPR001602 Uncharacterised protein family UPF0047 L21SP4_RS01970 aa4299048a6f685823b0ee7c16cf6b62 138 Gene3D G3DSA:2.60.120.460 1 138 4.4E-46 T 22-04-2016 IPR001602 Uncharacterised protein family UPF0047 L21SP4_RS01970 aa4299048a6f685823b0ee7c16cf6b62 138 SUPERFAMILY SSF111038 1 138 4.45E-45 T 22-04-2016 IPR001602 Uncharacterised protein family UPF0047 L21SP4_RS01970 aa4299048a6f685823b0ee7c16cf6b62 138 PANTHER PTHR30615 1 138 1.4E-87 T 22-04-2016 L21SP4_RS08665 e31b9341ef82adf9c8ae24d95a473f83 185 Pfam PF08843 Nucleotidyl transferase AbiEii toxin, Type IV TA system 21 163 7.0E-7 T 22-04-2016 IPR014942 Nucleotidyl transferase AbiEii toxin, Type IV TA system L21SP4_RS08665 e31b9341ef82adf9c8ae24d95a473f83 185 SUPERFAMILY SSF81301 10 129 5.89E-15 T 22-04-2016 L21SP4_RS09590 f57fb19ea34f772a1ecf0ffb254b0508 192 SUPERFAMILY SSF53335 22 189 1.22E-20 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS09590 f57fb19ea34f772a1ecf0ffb254b0508 192 Gene3D G3DSA:3.40.50.150 24 187 8.0E-22 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS09590 f57fb19ea34f772a1ecf0ffb254b0508 192 Pfam PF08241 Methyltransferase domain 26 113 7.7E-12 T 22-04-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 L21SP4_RS09590 f57fb19ea34f772a1ecf0ffb254b0508 192 PANTHER PTHR10108 25 177 1.7E-12 T 22-04-2016 L21SP4_RS09645 e0bb1ad231760d0e4b2019e82d4b9566 462 Pfam PF04986 Putative transposase 175 342 7.6E-26 T 22-04-2016 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 L21SP4_RS09645 e0bb1ad231760d0e4b2019e82d4b9566 462 Pfam PF14319 Transposase zinc-binding domain 34 148 2.2E-19 T 22-04-2016 IPR026889 Transposase zinc-binding domain L21SP4_RS09675 514ebc3722dee445fd709c1ad4fa8d72 134 SUPERFAMILY SSF52540 23 122 3.07E-7 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS03020 1374199c21fbd9baca144d5dd7e866e7 351 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 13 336 7.7E-57 T 22-04-2016 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase L21SP4_RS03020 1374199c21fbd9baca144d5dd7e866e7 351 PANTHER PTHR30244:SF3 1 349 3.4E-44 T 22-04-2016 L21SP4_RS03020 1374199c21fbd9baca144d5dd7e866e7 351 Gene3D G3DSA:3.90.1150.10 237 346 5.9E-7 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 L21SP4_RS03020 1374199c21fbd9baca144d5dd7e866e7 351 PIRSF PIRSF000390 1 349 4.7E-58 T 22-04-2016 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase L21SP4_RS03020 1374199c21fbd9baca144d5dd7e866e7 351 Gene3D G3DSA:3.40.640.10 2 227 3.0E-47 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 L21SP4_RS03020 1374199c21fbd9baca144d5dd7e866e7 351 SUPERFAMILY SSF53383 2 345 1.89E-64 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase L21SP4_RS03020 1374199c21fbd9baca144d5dd7e866e7 351 PANTHER PTHR30244 1 349 3.4E-44 T 22-04-2016 L21SP4_RS00960 80909603e87636747735b0c494be0860 346 PANTHER PTHR22916 1 220 6.4E-42 T 22-04-2016 L21SP4_RS00960 80909603e87636747735b0c494be0860 346 Pfam PF00535 Glycosyl transferase family 2 4 174 5.1E-31 T 22-04-2016 IPR001173 Glycosyltransferase 2-like L21SP4_RS00960 80909603e87636747735b0c494be0860 346 Gene3D G3DSA:3.90.550.10 1 220 5.9E-46 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases L21SP4_RS00960 80909603e87636747735b0c494be0860 346 SUPERFAMILY SSF53448 1 238 7.59E-53 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases L21SP4_RS05440 d9c2ca3ba5058ce1a447d739f912bbb3 324 SUPERFAMILY SSF81345 2 316 6.93E-77 T 22-04-2016 IPR029022 ABC transporter, BtuC-like L21SP4_RS05440 d9c2ca3ba5058ce1a447d739f912bbb3 324 Pfam PF01032 FecCD transport family 18 316 3.0E-85 T 22-04-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 L21SP4_RS05440 d9c2ca3ba5058ce1a447d739f912bbb3 324 Gene3D G3DSA:1.10.3470.10 2 319 2.5E-93 T 22-04-2016 IPR029022 ABC transporter, BtuC-like L21SP4_RS05440 d9c2ca3ba5058ce1a447d739f912bbb3 324 PANTHER PTHR30472 1 323 2.2E-99 T 22-04-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 L21SP4_RS08860 06554ebbe1f680f19b8ecf23e60c86f8 567 SUPERFAMILY SSF51445 49 379 1.0E-21 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily L21SP4_RS04385 b1946f10265e820817c134435a6d611b 368 SUPERFAMILY SSF51726 1 69 4.97E-24 T 22-04-2016 L21SP4_RS04385 b1946f10265e820817c134435a6d611b 368 SUPERFAMILY SSF51726 116 367 4.97E-24 T 22-04-2016 L21SP4_RS04385 b1946f10265e820817c134435a6d611b 368 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 182 364 5.4E-17 T 22-04-2016 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 L21SP4_RS04385 b1946f10265e820817c134435a6d611b 368 Gene3D G3DSA:3.20.20.210 1 365 1.2E-26 T 22-04-2016 L21SP4_RS02140 6d3538ec10eba5f98948bb9ca02712b9 144 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 4 141 2.5E-53 T 22-04-2016 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 L21SP4_RS02140 6d3538ec10eba5f98948bb9ca02712b9 144 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 15 141 27.418 T 22-04-2016 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 L21SP4_RS02140 6d3538ec10eba5f98948bb9ca02712b9 144 Pfam PF00572 Ribosomal protein L13 14 138 3.3E-50 T 22-04-2016 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 L21SP4_RS02140 6d3538ec10eba5f98948bb9ca02712b9 144 SUPERFAMILY SSF52161 1 139 1.1E-52 T 22-04-2016 IPR023564 Ribosomal protein L13 domain GO:0003735|GO:0005840|GO:0006412 L21SP4_RS02140 6d3538ec10eba5f98948bb9ca02712b9 144 PIRSF PIRSF002181 1 144 6.6E-49 T 22-04-2016 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 L21SP4_RS02140 6d3538ec10eba5f98948bb9ca02712b9 144 PANTHER PTHR11545 1 138 1.8E-62 T 22-04-2016 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 L21SP4_RS02140 6d3538ec10eba5f98948bb9ca02712b9 144 Gene3D G3DSA:3.90.1180.10 5 141 1.8E-55 T 22-04-2016 IPR023564 Ribosomal protein L13 domain GO:0003735|GO:0005840|GO:0006412 L21SP4_RS10200 8ad47f54b08172f1bd37ab09994e88e5 593 Gene3D G3DSA:3.40.50.300 2 187 2.4E-11 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS10200 8ad47f54b08172f1bd37ab09994e88e5 593 Pfam PF00270 DEAD/DEAH box helicase 2 182 2.9E-7 T 22-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 L21SP4_RS10200 8ad47f54b08172f1bd37ab09994e88e5 593 SMART SM00490 258 344 5.3E-5 T 22-04-2016 IPR001650 Helicase, C-terminal L21SP4_RS10200 8ad47f54b08172f1bd37ab09994e88e5 593 TIGRFAM TIGR01587 cas3_core: CRISPR-associated helicase Cas3 16 350 3.2E-66 T 22-04-2016 IPR006474 Helicase Cas3, CRISPR-associated, core L21SP4_RS10200 8ad47f54b08172f1bd37ab09994e88e5 593 Pfam PF00271 Helicase conserved C-terminal domain 227 343 6.7E-6 T 22-04-2016 IPR001650 Helicase, C-terminal L21SP4_RS10200 8ad47f54b08172f1bd37ab09994e88e5 593 Gene3D G3DSA:3.40.50.300 223 346 1.1E-11 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS10200 8ad47f54b08172f1bd37ab09994e88e5 593 SUPERFAMILY SSF52540 110 346 3.55E-30 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS10200 8ad47f54b08172f1bd37ab09994e88e5 593 SUPERFAMILY SSF52540 10 63 3.55E-30 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS02910 3470b2d7c213308141f870423e1151c2 137 PANTHER PTHR21256 27 126 2.4E-25 T 22-04-2016 L21SP4_RS02910 3470b2d7c213308141f870423e1151c2 137 SUPERFAMILY SSF141734 17 128 3.79E-31 T 22-04-2016 L21SP4_RS02910 3470b2d7c213308141f870423e1151c2 137 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 67 123 4.0E-9 T 22-04-2016 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19|UniPathway: UPA00031 L21SP4_RS02910 3470b2d7c213308141f870423e1151c2 137 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 44 121 1.2E-24 T 22-04-2016 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19|UniPathway: UPA00031 L21SP4_RS02185 50d09c0ecf23c29f29c2a0a8fccb7fb2 158 Pfam PF13490 Putative zinc-finger 6 37 1.8E-6 T 22-04-2016 IPR027383 Putative zinc-finger L21SP4_RS01795 100e953e52be3485f70acc9f46c07ecd 654 PANTHER PTHR11819:SF77 9 314 7.4E-47 T 22-04-2016 L21SP4_RS01795 100e953e52be3485f70acc9f46c07ecd 654 PANTHER PTHR11819:SF77 377 604 7.4E-47 T 22-04-2016 L21SP4_RS01795 100e953e52be3485f70acc9f46c07ecd 654 PANTHER PTHR11819:SF77 644 654 7.4E-47 T 22-04-2016 L21SP4_RS01795 100e953e52be3485f70acc9f46c07ecd 654 PANTHER PTHR11819 9 314 7.4E-47 T 22-04-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 L21SP4_RS01795 100e953e52be3485f70acc9f46c07ecd 654 PANTHER PTHR11819 377 604 7.4E-47 T 22-04-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 L21SP4_RS01795 100e953e52be3485f70acc9f46c07ecd 654 PANTHER PTHR11819 644 654 7.4E-47 T 22-04-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 L21SP4_RS01795 100e953e52be3485f70acc9f46c07ecd 654 Pfam PF00474 Sodium:solute symporter family 390 517 2.3E-15 T 22-04-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 L21SP4_RS01795 100e953e52be3485f70acc9f46c07ecd 654 Pfam PF00474 Sodium:solute symporter family 41 232 7.3E-14 T 22-04-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 L21SP4_RS06675 2402b3f1bbdfa60f5216b8ee1ea6d817 515 PANTHER PTHR22901 2 225 6.7E-123 T 22-04-2016 L21SP4_RS06675 2402b3f1bbdfa60f5216b8ee1ea6d817 515 PANTHER PTHR22901 249 514 6.7E-123 T 22-04-2016 L21SP4_RS06675 2402b3f1bbdfa60f5216b8ee1ea6d817 515 Pfam PF03629 Carbohydrate esterase, sialic acid-specific acetylesterase 106 402 3.2E-78 T 22-04-2016 IPR005181 Sialate O-acetylesterase domain L21SP4_RS06675 2402b3f1bbdfa60f5216b8ee1ea6d817 515 SUPERFAMILY SSF52266 283 464 5.68E-66 T 22-04-2016 IPR013830 SGNH hydrolase-type esterase domain L21SP4_RS06675 2402b3f1bbdfa60f5216b8ee1ea6d817 515 SUPERFAMILY SSF52266 106 209 5.68E-66 T 22-04-2016 IPR013830 SGNH hydrolase-type esterase domain L21SP4_RS06675 2402b3f1bbdfa60f5216b8ee1ea6d817 515 PANTHER PTHR22901:SF0 2 225 6.7E-123 T 22-04-2016 L21SP4_RS06675 2402b3f1bbdfa60f5216b8ee1ea6d817 515 PANTHER PTHR22901:SF0 249 514 6.7E-123 T 22-04-2016 L21SP4_RS07055 61443a478b35e886a2dc5c09db3623c0 392 Pfam PF01676 Metalloenzyme superfamily 3 386 2.7E-8 T 22-04-2016 IPR006124 Metalloenzyme GO:0003824|GO:0046872 L21SP4_RS07055 61443a478b35e886a2dc5c09db3623c0 392 Pfam PF10143 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 76 200 4.5E-10 T 22-04-2016 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 L21SP4_RS07055 61443a478b35e886a2dc5c09db3623c0 392 SUPERFAMILY SSF53649 4 69 1.7E-5 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS07055 61443a478b35e886a2dc5c09db3623c0 392 SUPERFAMILY SSF53649 184 367 1.7E-5 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS07055 61443a478b35e886a2dc5c09db3623c0 392 PANTHER PTHR31209:SF4 1 227 1.0E-19 T 22-04-2016 L21SP4_RS07055 61443a478b35e886a2dc5c09db3623c0 392 PANTHER PTHR31209 1 227 1.0E-19 T 22-04-2016 L21SP4_RS05700 e88452d80e3aa30a72f5711b2c95f1da 200 PANTHER PTHR36118:SF1 17 193 4.1E-23 T 22-04-2016 L21SP4_RS05700 e88452d80e3aa30a72f5711b2c95f1da 200 SMART SM00900 102 192 9.7E-25 T 22-04-2016 IPR007329 FMN-binding GO:0010181|GO:0016020 L21SP4_RS05700 e88452d80e3aa30a72f5711b2c95f1da 200 Pfam PF04205 FMN-binding domain 102 189 6.7E-19 T 22-04-2016 IPR007329 FMN-binding GO:0010181|GO:0016020 L21SP4_RS05700 e88452d80e3aa30a72f5711b2c95f1da 200 Hamap MF_00479 Electron transport complex subunit RsxG [rsxG]. 17 194 22.065 T 22-04-2016 IPR010209 Electron transport complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 L21SP4_RS05700 e88452d80e3aa30a72f5711b2c95f1da 200 PANTHER PTHR36118 17 193 4.1E-23 T 22-04-2016 L21SP4_RS05700 e88452d80e3aa30a72f5711b2c95f1da 200 PIRSF PIRSF006091 11 200 2.6E-33 T 22-04-2016 IPR010209 Electron transport complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 L21SP4_RS02765 b6d91f9b1dc9b103e85929863523dbe1 306 PANTHER PTHR30465 14 306 2.0E-102 T 22-04-2016 L21SP4_RS02765 b6d91f9b1dc9b103e85929863523dbe1 306 Gene3D G3DSA:1.10.3720.10 94 302 9.7E-28 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 L21SP4_RS02765 b6d91f9b1dc9b103e85929863523dbe1 306 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 122 305 4.3E-27 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 L21SP4_RS02765 b6d91f9b1dc9b103e85929863523dbe1 306 PANTHER PTHR30465:SF2 14 306 2.0E-102 T 22-04-2016 L21SP4_RS02765 b6d91f9b1dc9b103e85929863523dbe1 306 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 21 81 1.7E-13 T 22-04-2016 IPR025966 Oligopeptide transport permease C-like, N-terminal domain L21SP4_RS02765 b6d91f9b1dc9b103e85929863523dbe1 306 SUPERFAMILY SSF161098 99 288 1.83E-24 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 L21SP4_RS01740 28284d6a780739c76ba870daf2ce4043 404 Pfam PF01609 Transposase DDE domain 81 331 6.2E-8 T 22-04-2016 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 L21SP4_RS01740 28284d6a780739c76ba870daf2ce4043 404 SUPERFAMILY SSF53098 77 337 5.54E-19 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS01740 28284d6a780739c76ba870daf2ce4043 404 Gene3D G3DSA:3.90.350.10 77 313 2.8E-17 T 22-04-2016 IPR014736 Transposase, Tn5-like, core L21SP4_RS02800 ac9465d2cf10b5b95eda3f0ff05f39aa 432 Gene3D G3DSA:3.20.20.80 31 428 5.2E-34 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP4_RS02800 ac9465d2cf10b5b95eda3f0ff05f39aa 432 SUPERFAMILY SSF51445 30 392 1.75E-30 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily L21SP4_RS02800 ac9465d2cf10b5b95eda3f0ff05f39aa 432 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 79 370 1.1E-8 T 22-04-2016 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 L21SP4_RS01635 0bf1fb0e137e73986226e42c6cc2ac91 395 Gene3D G3DSA:3.40.50.1820 324 390 3.2E-5 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold L21SP4_RS01635 0bf1fb0e137e73986226e42c6cc2ac91 395 Gene3D G3DSA:3.40.50.1820 158 258 3.2E-5 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold L21SP4_RS01635 0bf1fb0e137e73986226e42c6cc2ac91 395 SUPERFAMILY SSF53474 293 367 5.86E-10 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold L21SP4_RS01635 0bf1fb0e137e73986226e42c6cc2ac91 395 SUPERFAMILY SSF53474 157 238 5.86E-10 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold L21SP4_RS06550 d8ee66ea4ecbe406617221e597b42e44 415 Gene3D G3DSA:3.30.1120.10 347 406 9.4E-13 T 22-04-2016 L21SP4_RS06550 d8ee66ea4ecbe406617221e597b42e44 415 PANTHER PTHR10342:SF207 6 397 2.2E-74 T 22-04-2016 L21SP4_RS06550 d8ee66ea4ecbe406617221e597b42e44 415 PANTHER PTHR10342 6 397 2.2E-74 T 22-04-2016 L21SP4_RS06550 d8ee66ea4ecbe406617221e597b42e44 415 SUPERFAMILY SSF53649 8 398 3.34E-88 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS06550 d8ee66ea4ecbe406617221e597b42e44 415 Pfam PF00884 Sulfatase 9 308 4.0E-45 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS06550 d8ee66ea4ecbe406617221e597b42e44 415 Gene3D G3DSA:3.40.720.10 7 346 4.9E-66 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS05085 ef79afe36fe9fabf264c190800a839ef 365 PANTHER PTHR12383 222 364 3.8E-32 T 22-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 L21SP4_RS05085 ef79afe36fe9fabf264c190800a839ef 365 PANTHER PTHR12383 81 121 3.8E-32 T 22-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 L21SP4_RS05085 ef79afe36fe9fabf264c190800a839ef 365 Pfam PF10502 Signal peptidase, peptidase S26 251 350 1.8E-8 T 22-04-2016 IPR019533 Peptidase S26 L21SP4_RS05085 ef79afe36fe9fabf264c190800a839ef 365 Gene3D G3DSA:2.10.109.10 99 119 1.9E-37 T 22-04-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain L21SP4_RS05085 ef79afe36fe9fabf264c190800a839ef 365 Gene3D G3DSA:2.10.109.10 221 269 1.9E-37 T 22-04-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain L21SP4_RS05085 ef79afe36fe9fabf264c190800a839ef 365 Gene3D G3DSA:2.10.109.10 317 363 1.9E-37 T 22-04-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain L21SP4_RS05085 ef79afe36fe9fabf264c190800a839ef 365 SUPERFAMILY SSF51306 100 119 3.14E-34 T 22-04-2016 IPR015927 Peptidase S24/S26A/S26B/S26C L21SP4_RS05085 ef79afe36fe9fabf264c190800a839ef 365 SUPERFAMILY SSF51306 221 363 3.14E-34 T 22-04-2016 IPR015927 Peptidase S24/S26A/S26B/S26C L21SP4_RS05085 ef79afe36fe9fabf264c190800a839ef 365 PANTHER PTHR12383:SF14 222 364 3.8E-32 T 22-04-2016 L21SP4_RS05085 ef79afe36fe9fabf264c190800a839ef 365 PANTHER PTHR12383:SF14 81 121 3.8E-32 T 22-04-2016 L21SP4_RS05085 ef79afe36fe9fabf264c190800a839ef 365 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 220 358 8.9E-27 T 22-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 L21SP4_RS05085 ef79afe36fe9fabf264c190800a839ef 365 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 102 118 4.1E-9 T 22-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 L21SP4_RS05085 ef79afe36fe9fabf264c190800a839ef 365 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 317 336 4.1E-9 T 22-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 L21SP4_RS01840 4f5153832da5c16a387835e800477eb2 366 SUPERFAMILY SSF51726 1 55 1.67E-33 T 22-04-2016 L21SP4_RS01840 4f5153832da5c16a387835e800477eb2 366 SUPERFAMILY SSF51726 92 363 1.67E-33 T 22-04-2016 L21SP4_RS01840 4f5153832da5c16a387835e800477eb2 366 Gene3D G3DSA:3.20.20.210 1 56 1.4E-36 T 22-04-2016 L21SP4_RS01840 4f5153832da5c16a387835e800477eb2 366 Gene3D G3DSA:3.20.20.210 89 363 1.4E-36 T 22-04-2016 L21SP4_RS01840 4f5153832da5c16a387835e800477eb2 366 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 155 363 2.5E-19 T 22-04-2016 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 L21SP4_RS05285 aaa3f03c94811126b14630ee17776938 136 Gene3D G3DSA:1.10.150.130 41 127 1.4E-6 T 22-04-2016 IPR023109 Integrase/recombinase, N-terminal L21SP4_RS08800 cb72a84b6efd947c550a7169068a6e2a 393 Gene3D G3DSA:3.40.50.2000 219 358 1.6E-23 T 22-04-2016 L21SP4_RS08800 cb72a84b6efd947c550a7169068a6e2a 393 SUPERFAMILY SSF53756 3 391 7.46E-57 T 22-04-2016 L21SP4_RS08800 cb72a84b6efd947c550a7169068a6e2a 393 Pfam PF00534 Glycosyl transferases group 1 214 362 3.1E-25 T 22-04-2016 IPR001296 Glycosyl transferase, family 1 L21SP4_RS08800 cb72a84b6efd947c550a7169068a6e2a 393 PANTHER PTHR12526 1 146 2.9E-43 T 22-04-2016 L21SP4_RS08800 cb72a84b6efd947c550a7169068a6e2a 393 PANTHER PTHR12526 164 392 2.9E-43 T 22-04-2016 L21SP4_RS00695 eaba7a393684ac45bd1d010a5f2b092b 172 Gene3D G3DSA:4.10.1080.10 90 151 2.7E-5 T 22-04-2016 IPR028974 TSP type-3 repeat GO:0005509 L21SP4_RS02060 d4047767b65605f27b8119f4a672d4f7 247 Gene3D G3DSA:3.30.700.10 1 54 1.4E-5 T 22-04-2016 L21SP4_RS02060 d4047767b65605f27b8119f4a672d4f7 247 PANTHER PTHR30093 2 83 2.6E-12 T 22-04-2016 L21SP4_RS02060 d4047767b65605f27b8119f4a672d4f7 247 SUPERFAMILY SSF54523 1 83 5.23E-13 T 22-04-2016 L21SP4_RS06845 e3f7547251d9331880d16348b8e6301f 207 SUPERFAMILY SSF53335 1 197 1.88E-37 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS06845 e3f7547251d9331880d16348b8e6301f 207 Pfam PF13489 Methyltransferase domain 29 183 3.9E-19 T 22-04-2016 L21SP4_RS06845 e3f7547251d9331880d16348b8e6301f 207 Gene3D G3DSA:3.40.50.150 4 186 4.2E-39 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS06845 e3f7547251d9331880d16348b8e6301f 207 PANTHER PTHR10108 11 199 2.8E-22 T 22-04-2016 L21SP4_RS08060 3d684f1edc630039b44804a629badf32 126 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 84 90 - T 22-04-2016 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 L21SP4_RS08060 3d684f1edc630039b44804a629badf32 126 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 35 112 1.4E-28 T 22-04-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 L21SP4_RS08060 3d684f1edc630039b44804a629badf32 126 PANTHER PTHR10815 13 112 1.3E-30 T 22-04-2016 L21SP4_RS08060 3d684f1edc630039b44804a629badf32 126 Gene3D G3DSA:1.10.10.10 33 118 2.3E-29 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS08060 3d684f1edc630039b44804a629badf32 126 SUPERFAMILY SSF46767 34 113 4.45E-26 T 22-04-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 L21SP4_RS08060 3d684f1edc630039b44804a629badf32 126 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 35 113 1.1E-26 T 22-04-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 L21SP4_RS09785 de3ca445a04a818195575e385c6be3bc 129 Pfam PF03186 CobD/Cbib protein 17 107 7.9E-12 T 22-04-2016 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 UniPathway: UPA00148 L21SP4_RS00750 8a1863cb77c170512165f87ed41d162b 151 Pfam PF02470 MlaD protein 37 113 4.6E-19 T 22-04-2016 IPR003399 Mce/MlaD L21SP4_RS00750 8a1863cb77c170512165f87ed41d162b 151 PANTHER PTHR33371 1 143 1.9E-35 T 22-04-2016 L21SP4_RS00750 8a1863cb77c170512165f87ed41d162b 151 TIGRFAM TIGR04430 OM_asym_MlaD: outer membrane lipid asymmetry maintenance protein MlaD 6 142 1.4E-42 T 22-04-2016 IPR030970 Probable phospholipid ABC transporter-binding protein MlaD GO:0015914 L21SP4_RS06270 4b5d8c39eea0f1585332a3a98973cfe0 218 SUPERFAMILY SSF160527 100 190 1.57E-5 T 22-04-2016 L21SP4_RS09730 d2945f16a70b0bbb75c1e6d2fd0b7c23 327 PANTHER PTHR34580 1 320 8.8E-63 T 22-04-2016 L21SP4_RS09730 d2945f16a70b0bbb75c1e6d2fd0b7c23 327 PANTHER PTHR34580:SF3 1 320 8.8E-63 T 22-04-2016 L21SP4_RS09730 d2945f16a70b0bbb75c1e6d2fd0b7c23 327 Pfam PF13280 WYL domain 151 321 4.2E-39 T 22-04-2016 IPR026881 WYL domain L21SP4_RS09730 d2945f16a70b0bbb75c1e6d2fd0b7c23 327 Gene3D G3DSA:1.10.10.10 30 72 3.0E-5 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS07760 09762ee9a6f9badfb91ab893b6f098b3 344 Gene3D G3DSA:3.40.50.150 154 323 1.1E-24 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS07760 09762ee9a6f9badfb91ab893b6f098b3 344 SUPERFAMILY SSF53335 117 325 2.76E-23 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS07760 09762ee9a6f9badfb91ab893b6f098b3 344 Pfam PF16864 Dimerisation domain 27 94 3.0E-9 T 22-04-2016 IPR031725 Acetylserotonin O-methyltransferase, dimerisation domain L21SP4_RS07760 09762ee9a6f9badfb91ab893b6f098b3 344 Gene3D G3DSA:1.10.10.10 12 87 3.4E-16 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS07760 09762ee9a6f9badfb91ab893b6f098b3 344 Pfam PF00891 O-methyltransferase 165 288 4.7E-12 T 22-04-2016 IPR001077 O-methyltransferase, family 2 GO:0008171 L21SP4_RS07760 09762ee9a6f9badfb91ab893b6f098b3 344 PANTHER PTHR11746 28 231 3.3E-16 T 22-04-2016 L21SP4_RS07760 09762ee9a6f9badfb91ab893b6f098b3 344 SUPERFAMILY SSF46785 15 92 1.6E-7 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS08025 63542c83d2d2f01e560359c35c778e12 621 Gene3D G3DSA:3.40.50.300 168 352 4.1E-60 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS08025 63542c83d2d2f01e560359c35c778e12 621 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 2 619 34.888 T 22-04-2016 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 L21SP4_RS08025 63542c83d2d2f01e560359c35c778e12 621 Gene3D G3DSA:1.10.8.60 353 423 2.6E-24 T 22-04-2016 L21SP4_RS08025 63542c83d2d2f01e560359c35c778e12 621 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 112 611 3.2E-207 T 22-04-2016 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 L21SP4_RS08025 63542c83d2d2f01e560359c35c778e12 621 PANTHER PTHR23076 1 617 2.6E-273 T 22-04-2016 L21SP4_RS08025 63542c83d2d2f01e560359c35c778e12 621 SMART SM00382 205 344 1.4E-22 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS08025 63542c83d2d2f01e560359c35c778e12 621 SUPERFAMILY SSF140990 423 616 1.02E-69 T 22-04-2016 L21SP4_RS08025 63542c83d2d2f01e560359c35c778e12 621 ProSitePatterns PS00674 AAA-protein family signature. 312 330 - T 22-04-2016 IPR003960 ATPase, AAA-type, conserved site GO:0005524 L21SP4_RS08025 63542c83d2d2f01e560359c35c778e12 621 SUPERFAMILY SSF52540 169 412 4.51E-69 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS08025 63542c83d2d2f01e560359c35c778e12 621 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 209 340 1.5E-43 T 22-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 L21SP4_RS08025 63542c83d2d2f01e560359c35c778e12 621 Pfam PF01434 Peptidase family M41 403 610 4.7E-74 T 22-04-2016 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 L21SP4_RS11400 4be8783eb12c1754bdf2485dcdc5bf47 344 SMART SM00354 3 69 1.7E-4 T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 L21SP4_RS11400 4be8783eb12c1754bdf2485dcdc5bf47 344 PANTHER PTHR30146 3 344 2.2E-71 T 22-04-2016 L21SP4_RS11400 4be8783eb12c1754bdf2485dcdc5bf47 344 Gene3D G3DSA:3.40.50.2300 72 173 9.6E-13 T 22-04-2016 L21SP4_RS11400 4be8783eb12c1754bdf2485dcdc5bf47 344 Gene3D G3DSA:3.40.50.2300 174 337 9.1E-47 T 22-04-2016 L21SP4_RS11400 4be8783eb12c1754bdf2485dcdc5bf47 344 Gene3D G3DSA:1.10.260.40 1 51 1.3E-13 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 L21SP4_RS11400 4be8783eb12c1754bdf2485dcdc5bf47 344 SUPERFAMILY SSF53822 73 338 2.36E-50 T 22-04-2016 IPR028082 Periplasmic binding protein-like I L21SP4_RS11400 4be8783eb12c1754bdf2485dcdc5bf47 344 SUPERFAMILY SSF47413 1 52 8.09E-11 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 L21SP4_RS11400 4be8783eb12c1754bdf2485dcdc5bf47 344 Pfam PF13377 Periplasmic binding protein-like domain 170 336 2.3E-33 T 22-04-2016 L21SP4_RS11400 4be8783eb12c1754bdf2485dcdc5bf47 344 Pfam PF00356 Bacterial regulatory proteins, lacI family 13 49 3.0E-7 T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 L21SP4_RS01495 9df8daf4b8166c9be01f3d4a7b17da18 159 Gene3D G3DSA:3.30.310.70 29 135 6.9E-20 T 22-04-2016 IPR005180 Domain of unknown function DUF302 L21SP4_RS01495 9df8daf4b8166c9be01f3d4a7b17da18 159 PANTHER PTHR38342 1 148 6.1E-15 T 22-04-2016 L21SP4_RS01495 9df8daf4b8166c9be01f3d4a7b17da18 159 Pfam PF03625 Domain of unknown function DUF302 63 126 9.1E-14 T 22-04-2016 IPR005180 Domain of unknown function DUF302 L21SP4_RS01495 9df8daf4b8166c9be01f3d4a7b17da18 159 SUPERFAMILY SSF103247 29 137 3.92E-21 T 22-04-2016 IPR005180 Domain of unknown function DUF302 L21SP4_RS07630 b3dd4c14df652a67befcac82ef06862a 391 Pfam PF01145 SPFH domain / Band 7 family 50 259 6.7E-16 T 22-04-2016 IPR001107 Band 7 domain L21SP4_RS00060 26354c6eb06107ddd55d04769c4f1734 293 PIRSF PIRSF005355 1 292 1.3E-58 T 22-04-2016 IPR026046 UbiA prenyltransferase domain containing protein 1 GO:0004659 L21SP4_RS00060 26354c6eb06107ddd55d04769c4f1734 293 Pfam PF01040 UbiA prenyltransferase family 20 265 9.8E-32 T 22-04-2016 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 L21SP4_RS00060 26354c6eb06107ddd55d04769c4f1734 293 PANTHER PTHR13929 2 289 3.1E-60 T 22-04-2016 L21SP4_RS00060 26354c6eb06107ddd55d04769c4f1734 293 PANTHER PTHR13929:SF0 2 289 3.1E-60 T 22-04-2016 L21SP4_RS11535 b5ce7e98724e11461732c026039ae74a 935 SUPERFAMILY SSF52540 263 602 2.92E-10 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS11535 b5ce7e98724e11461732c026039ae74a 935 Pfam PF12705 PD-(D/E)XK nuclease superfamily 644 901 4.2E-23 T 22-04-2016 L21SP4_RS05510 abb26e016167c5b0e803772888af2220 145 PANTHER PTHR11241:SF0 23 144 2.1E-21 T 22-04-2016 L21SP4_RS05510 abb26e016167c5b0e803772888af2220 145 SUPERFAMILY SSF51283 23 144 1.16E-30 T 22-04-2016 IPR029054 dUTPase-like L21SP4_RS05510 abb26e016167c5b0e803772888af2220 145 Pfam PF00692 dUTPase 24 144 1.1E-17 T 22-04-2016 IPR008180 Deoxyuridine triphosphate nucleotidohydrolase/Deoxycytidine triphosphate deaminase GO:0016787|GO:0046080 L21SP4_RS05510 abb26e016167c5b0e803772888af2220 145 PANTHER PTHR11241 23 144 2.1E-21 T 22-04-2016 L21SP4_RS05510 abb26e016167c5b0e803772888af2220 145 Gene3D G3DSA:2.70.40.10 23 144 5.3E-37 T 22-04-2016 IPR029054 dUTPase-like L21SP4_RS08775 28dfb30e2567ffad1cbf4808fd8d957e 271 SUPERFAMILY SSF52540 3 46 4.18E-13 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS08775 28dfb30e2567ffad1cbf4808fd8d957e 271 SUPERFAMILY SSF52540 109 222 4.18E-13 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS07980 2cdd3afb977dc91744d8bdcf1c715e9e 165 Gene3D G3DSA:3.40.250.10 53 152 2.5E-16 T 22-04-2016 IPR001763 Rhodanese-like domain L21SP4_RS07980 2cdd3afb977dc91744d8bdcf1c715e9e 165 SMART SM00450 57 153 2.3E-12 T 22-04-2016 IPR001763 Rhodanese-like domain L21SP4_RS07980 2cdd3afb977dc91744d8bdcf1c715e9e 165 SUPERFAMILY SSF52821 56 153 2.88E-19 T 22-04-2016 IPR001763 Rhodanese-like domain L21SP4_RS07980 2cdd3afb977dc91744d8bdcf1c715e9e 165 Pfam PF00581 Rhodanese-like domain 60 149 1.8E-10 T 22-04-2016 IPR001763 Rhodanese-like domain L21SP4_RS00205 f1a3a852be88aff3f28bd7b65fa78c61 99 SMART SM00507 28 79 3.1E-11 T 22-04-2016 IPR003615 HNH nuclease L21SP4_RS00205 f1a3a852be88aff3f28bd7b65fa78c61 99 PANTHER PTHR33877 15 92 4.1E-18 T 22-04-2016 L21SP4_RS00205 f1a3a852be88aff3f28bd7b65fa78c61 99 Pfam PF14279 HNH endonuclease 39 88 2.3E-14 T 22-04-2016 IPR029471 HNH endonuclease 5 L21SP4_RS01870 bf8eae7e78403d1cf764f45f05b004ae 131 Gene3D G3DSA:3.40.30.10 30 124 7.7E-22 T 22-04-2016 IPR012336 Thioredoxin-like fold L21SP4_RS01870 bf8eae7e78403d1cf764f45f05b004ae 131 PANTHER PTHR11780:SF0 29 122 2.2E-25 T 22-04-2016 L21SP4_RS01870 bf8eae7e78403d1cf764f45f05b004ae 131 PANTHER PTHR11780 29 122 2.2E-25 T 22-04-2016 L21SP4_RS01870 bf8eae7e78403d1cf764f45f05b004ae 131 SUPERFAMILY SSF52833 29 120 8.2E-18 T 22-04-2016 IPR012336 Thioredoxin-like fold L21SP4_RS02710 ee903d361a5690fa64b4d3cb3e35873f 274 Gene3D G3DSA:1.10.600.10 25 231 7.8E-51 T 22-04-2016 IPR008949 Isoprenoid synthase domain L21SP4_RS02710 ee903d361a5690fa64b4d3cb3e35873f 274 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 65 79 - T 22-04-2016 IPR000092 Polyprenyl synthetase GO:0008299 L21SP4_RS02710 ee903d361a5690fa64b4d3cb3e35873f 274 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 184 196 - T 22-04-2016 IPR000092 Polyprenyl synthetase GO:0008299 L21SP4_RS02710 ee903d361a5690fa64b4d3cb3e35873f 274 Pfam PF00348 Polyprenyl synthetase 25 226 6.5E-37 T 22-04-2016 IPR000092 Polyprenyl synthetase GO:0008299 L21SP4_RS02710 ee903d361a5690fa64b4d3cb3e35873f 274 PANTHER PTHR12001 1 269 6.1E-44 T 22-04-2016 IPR017446 Polyprenyl synthetase-related L21SP4_RS02710 ee903d361a5690fa64b4d3cb3e35873f 274 SUPERFAMILY SSF48576 17 225 7.92E-51 T 22-04-2016 IPR008949 Isoprenoid synthase domain L21SP4_RS09280 15465384e7b3654fa881364a6f1af42c 152 Pfam PF13620 Carboxypeptidase regulatory-like domain 36 96 2.6E-7 T 22-04-2016 L21SP4_RS09280 15465384e7b3654fa881364a6f1af42c 152 Gene3D G3DSA:2.60.40.10 35 95 2.6E-7 T 22-04-2016 IPR013783 Immunoglobulin-like fold L21SP4_RS09280 15465384e7b3654fa881364a6f1af42c 152 SUPERFAMILY SSF49464 35 104 3.92E-5 T 22-04-2016 IPR008969 Carboxypeptidase-like, regulatory domain L21SP4_RS00990 ca0d4b3186b3e12f5e4ee22ba35a7695 764 Gene3D G3DSA:3.40.50.300 541 730 2.9E-30 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS00990 ca0d4b3186b3e12f5e4ee22ba35a7695 764 PANTHER PTHR32309 4 460 2.1E-97 T 22-04-2016 L21SP4_RS00990 ca0d4b3186b3e12f5e4ee22ba35a7695 764 PANTHER PTHR32309 504 594 2.1E-97 T 22-04-2016 L21SP4_RS00990 ca0d4b3186b3e12f5e4ee22ba35a7695 764 PANTHER PTHR32309 612 753 2.1E-97 T 22-04-2016 L21SP4_RS00990 ca0d4b3186b3e12f5e4ee22ba35a7695 764 Pfam PF13614 AAA domain 553 717 1.3E-8 T 22-04-2016 IPR025669 AAA domain L21SP4_RS00990 ca0d4b3186b3e12f5e4ee22ba35a7695 764 PANTHER PTHR32309:SF13 4 460 2.1E-97 T 22-04-2016 L21SP4_RS00990 ca0d4b3186b3e12f5e4ee22ba35a7695 764 PANTHER PTHR32309:SF13 504 594 2.1E-97 T 22-04-2016 L21SP4_RS00990 ca0d4b3186b3e12f5e4ee22ba35a7695 764 PANTHER PTHR32309:SF13 612 753 2.1E-97 T 22-04-2016 L21SP4_RS00990 ca0d4b3186b3e12f5e4ee22ba35a7695 764 Pfam PF02706 Chain length determinant protein 4 144 2.7E-13 T 22-04-2016 IPR003856 Lipopolysaccharide biosynthesis GO:0009103|GO:0016020 L21SP4_RS00990 ca0d4b3186b3e12f5e4ee22ba35a7695 764 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 522 742 5.9E-38 T 22-04-2016 IPR005702 Exopolysaccharide synthesis protein GO:0045226 L21SP4_RS00990 ca0d4b3186b3e12f5e4ee22ba35a7695 764 SUPERFAMILY SSF52540 541 738 4.08E-32 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS11655 f0d8a4abee88c9ea9e86595cb3bc383d 154 Pfam PF00665 Integrase core domain 3 106 8.5E-13 T 22-04-2016 IPR001584 Integrase, catalytic core GO:0015074 L21SP4_RS11655 f0d8a4abee88c9ea9e86595cb3bc383d 154 Gene3D G3DSA:3.30.420.10 3 146 4.4E-12 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS11655 f0d8a4abee88c9ea9e86595cb3bc383d 154 PANTHER PTHR10948 1 150 4.2E-45 T 22-04-2016 L21SP4_RS11655 f0d8a4abee88c9ea9e86595cb3bc383d 154 SUPERFAMILY SSF53098 2 147 5.46E-24 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS01985 3706561c0b4e6090e18c1336756bff29 590 Gene3D G3DSA:3.20.20.80 87 404 5.6E-27 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP4_RS01985 3706561c0b4e6090e18c1336756bff29 590 SUPERFAMILY SSF51445 121 408 6.96E-21 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily L21SP4_RS01985 3706561c0b4e6090e18c1336756bff29 590 Pfam PF01229 Glycosyl hydrolases family 39 119 274 3.1E-13 T 22-04-2016 IPR000514 Glycoside hydrolase, family 39 GO:0004553|GO:0005975 L21SP4_RS06945 6bc0bbee44e54cbd92623db0eb7a69c3 284 SUPERFAMILY SSF102588 25 229 4.58E-20 T 22-04-2016 IPR024078 Putative deacetylase LmbE-like domain L21SP4_RS06945 6bc0bbee44e54cbd92623db0eb7a69c3 284 Gene3D G3DSA:3.40.50.10320 25 219 2.6E-22 T 22-04-2016 IPR024078 Putative deacetylase LmbE-like domain L21SP4_RS06945 6bc0bbee44e54cbd92623db0eb7a69c3 284 Pfam PF02585 GlcNAc-PI de-N-acetylase 29 156 1.8E-10 T 22-04-2016 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related L21SP4_RS00475 f01613da531b84cdf7e9f7b0c49da671 295 Gene3D G3DSA:3.40.50.620 200 275 0.001 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP4_RS00475 f01613da531b84cdf7e9f7b0c49da671 295 Pfam PF01882 Protein of unknown function DUF58 45 130 5.7E-19 T 22-04-2016 IPR002881 Domain of unknown function DUF58 L21SP4_RS00475 f01613da531b84cdf7e9f7b0c49da671 295 PANTHER PTHR33608:SF2 9 290 5.7E-85 T 22-04-2016 L21SP4_RS00475 f01613da531b84cdf7e9f7b0c49da671 295 PANTHER PTHR33608 9 290 5.7E-85 T 22-04-2016 L21SP4_RS00475 f01613da531b84cdf7e9f7b0c49da671 295 SUPERFAMILY SSF53300 79 228 2.45E-18 T 22-04-2016 IPR002035 von Willebrand factor, type A L21SP4_RS08840 2ad0d1a00a3834b2b2c8ace7fad66fbe 409 SUPERFAMILY SSF52540 12 136 2.3E-10 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS08840 2ad0d1a00a3834b2b2c8ace7fad66fbe 409 Pfam PF13173 AAA domain 19 139 2.4E-19 T 22-04-2016 L21SP4_RS08840 2ad0d1a00a3834b2b2c8ace7fad66fbe 409 PANTHER PTHR33295:SF4 10 405 3.3E-61 T 22-04-2016 L21SP4_RS08840 2ad0d1a00a3834b2b2c8ace7fad66fbe 409 SUPERFAMILY SSF52980 308 388 5.63E-5 T 22-04-2016 IPR011335 Restriction endonuclease type II-like L21SP4_RS08840 2ad0d1a00a3834b2b2c8ace7fad66fbe 409 PANTHER PTHR33295 10 405 3.3E-61 T 22-04-2016 L21SP4_RS08840 2ad0d1a00a3834b2b2c8ace7fad66fbe 409 Gene3D G3DSA:3.40.50.300 11 132 4.9E-9 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS08840 2ad0d1a00a3834b2b2c8ace7fad66fbe 409 Pfam PF13635 Domain of unknown function (DUF4143) 220 359 8.3E-19 T 22-04-2016 IPR025420 Domain of unknown function DUF4143 L21SP4_RS06600 77da958d96555ae2d0a224fa97a01568 546 Pfam PF02706 Chain length determinant protein 4 144 9.1E-14 T 22-04-2016 IPR003856 Lipopolysaccharide biosynthesis GO:0009103|GO:0016020 L21SP4_RS06600 77da958d96555ae2d0a224fa97a01568 546 PANTHER PTHR32309:SF13 4 459 2.6E-43 T 22-04-2016 L21SP4_RS06600 77da958d96555ae2d0a224fa97a01568 546 PANTHER PTHR32309:SF13 503 530 2.6E-43 T 22-04-2016 L21SP4_RS06600 77da958d96555ae2d0a224fa97a01568 546 PANTHER PTHR32309 4 459 2.6E-43 T 22-04-2016 L21SP4_RS06600 77da958d96555ae2d0a224fa97a01568 546 PANTHER PTHR32309 503 530 2.6E-43 T 22-04-2016 L21SP4_RS04905 e909c7d5b56a8471a51db2315ae7b37a 275 PANTHER PTHR34138:SF1 3 259 1.3E-54 T 22-04-2016 L21SP4_RS04905 e909c7d5b56a8471a51db2315ae7b37a 275 PANTHER PTHR34138 3 259 1.3E-54 T 22-04-2016 L21SP4_RS04905 e909c7d5b56a8471a51db2315ae7b37a 275 TIGRFAM TIGR00219 mreC: rod shape-determining protein MreC 65 262 2.5E-37 T 22-04-2016 IPR007221 Rod shape-determining protein MreC GO:0008360 L21SP4_RS04905 e909c7d5b56a8471a51db2315ae7b37a 275 Pfam PF04085 rod shape-determining protein MreC 110 259 1.1E-37 T 22-04-2016 IPR007221 Rod shape-determining protein MreC GO:0008360 L21SP4_RS04905 e909c7d5b56a8471a51db2315ae7b37a 275 PIRSF PIRSF038471 5 273 5.3E-56 T 22-04-2016 IPR007221 Rod shape-determining protein MreC GO:0008360 L21SP4_RS08380 b04f20ff125eb798187f047371e91e41 115 PANTHER PTHR13501 1 115 1.5E-38 T 22-04-2016 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 L21SP4_RS08380 b04f20ff125eb798187f047371e91e41 115 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 1 110 25.732 T 22-04-2016 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 L21SP4_RS08380 b04f20ff125eb798187f047371e91e41 115 Gene3D G3DSA:3.90.470.10 1 111 4.3E-38 T 22-04-2016 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 L21SP4_RS08380 b04f20ff125eb798187f047371e91e41 115 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 5 106 1.9E-35 T 22-04-2016 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 L21SP4_RS08380 b04f20ff125eb798187f047371e91e41 115 SUPERFAMILY SSF54843 1 110 4.32E-37 T 22-04-2016 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 L21SP4_RS08380 b04f20ff125eb798187f047371e91e41 115 Pfam PF00237 Ribosomal protein L22p/L17e 8 108 2.2E-30 T 22-04-2016 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 L21SP4_RS09845 e0be5e04553c19879be03575914fd569 141 Pfam PF00872 Transposase, Mutator family 2 93 3.3E-5 T 22-04-2016 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 L21SP4_RS11455 ca7a79f247775b1128775e2dcc1f1398 212 PANTHER PTHR30625 4 201 1.3E-37 T 22-04-2016 L21SP4_RS11455 ca7a79f247775b1128775e2dcc1f1398 212 PANTHER PTHR30625:SF8 4 201 1.3E-37 T 22-04-2016 L21SP4_RS11455 ca7a79f247775b1128775e2dcc1f1398 212 Pfam PF01618 MotA/TolQ/ExbB proton channel family 69 189 2.6E-28 T 22-04-2016 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 L21SP4_RS08525 e62ae427506a6aa0484c577f10576f23 66 Gene3D G3DSA:3.10.20.30 1 66 5.2E-21 T 22-04-2016 IPR012675 Beta-grasp domain L21SP4_RS08525 e62ae427506a6aa0484c577f10576f23 66 PANTHER PTHR34472 1 66 1.6E-16 T 22-04-2016 L21SP4_RS08525 e62ae427506a6aa0484c577f10576f23 66 Pfam PF02597 ThiS family 5 66 9.2E-13 T 22-04-2016 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 L21SP4_RS08525 e62ae427506a6aa0484c577f10576f23 66 PANTHER PTHR34472:SF1 1 66 1.6E-16 T 22-04-2016 L21SP4_RS08525 e62ae427506a6aa0484c577f10576f23 66 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 3 66 1.9E-18 T 22-04-2016 IPR010035 ThiS, thiamine-biosynthesis L21SP4_RS08525 e62ae427506a6aa0484c577f10576f23 66 SUPERFAMILY SSF54285 1 66 2.62E-16 T 22-04-2016 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp L21SP4_RS11335 57219caac21767945f3c887ecab78bb5 136 TIGRFAM TIGR01987 HI0074: nucleotidyltransferase substrate binding protein, HI0074 family 12 130 5.8E-27 T 22-04-2016 IPR010235 Nucleotidyltransferase substrate binding protein, HI0074 L21SP4_RS11335 57219caac21767945f3c887ecab78bb5 136 Pfam PF08780 Nucleotidyltransferase substrate binding protein like 11 130 2.5E-42 T 22-04-2016 IPR010235 Nucleotidyltransferase substrate binding protein, HI0074 L21SP4_RS11335 57219caac21767945f3c887ecab78bb5 136 SUPERFAMILY SSF81593 6 130 2.04E-41 T 22-04-2016 L21SP4_RS11335 57219caac21767945f3c887ecab78bb5 136 Gene3D G3DSA:1.20.120.330 6 131 3.1E-48 T 22-04-2016 L21SP4_RS06610 ff71f3fba7ca4ba0c6300e3b811ca133 269 Pfam PF14236 Domain of unknown function (DUF4338) 30 256 3.5E-65 T 22-04-2016 IPR025639 Domain of unknown function DUF4338 L21SP4_RS06560 ff71f3fba7ca4ba0c6300e3b811ca133 269 Pfam PF14236 Domain of unknown function (DUF4338) 30 256 3.5E-65 T 22-04-2016 IPR025639 Domain of unknown function DUF4338 L21SP4_RS05465 1bce7da903ef8c22f1a5be56d868d819 178 Pfam PF00881 Nitroreductase family 9 158 4.2E-26 T 22-04-2016 IPR029479 Nitroreductase L21SP4_RS05465 1bce7da903ef8c22f1a5be56d868d819 178 PANTHER PTHR23026 1 174 9.5E-34 T 22-04-2016 L21SP4_RS05465 1bce7da903ef8c22f1a5be56d868d819 178 Gene3D G3DSA:3.40.109.10 1 174 7.8E-43 T 22-04-2016 IPR000415 Nitroreductase-like GO:0016491 L21SP4_RS05465 1bce7da903ef8c22f1a5be56d868d819 178 SUPERFAMILY SSF55469 1 175 1.19E-42 T 22-04-2016 IPR000415 Nitroreductase-like GO:0016491 L21SP4_RS05255 7b7ac997022912bd6f37fff438e5989c 328 PANTHER PTHR11732 9 327 3.2E-161 T 22-04-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta L21SP4_RS05255 7b7ac997022912bd6f37fff438e5989c 328 Pfam PF00248 Aldo/keto reductase family 24 324 1.2E-64 T 22-04-2016 IPR023210 NADP-dependent oxidoreductase domain L21SP4_RS05255 7b7ac997022912bd6f37fff438e5989c 328 Gene3D G3DSA:3.20.20.100 8 326 1.0E-87 T 22-04-2016 IPR023210 NADP-dependent oxidoreductase domain L21SP4_RS05255 7b7ac997022912bd6f37fff438e5989c 328 PANTHER PTHR11732:SF191 9 327 3.2E-161 T 22-04-2016 L21SP4_RS05255 7b7ac997022912bd6f37fff438e5989c 328 SUPERFAMILY SSF51430 9 325 1.7E-86 T 22-04-2016 IPR023210 NADP-dependent oxidoreductase domain L21SP4_RS04535 90ce625d0ec17572715d1dec45ed1b32 514 ProSitePatterns PS00523 Sulfatases signature 1. 62 74 - T 22-04-2016 IPR024607 Sulfatase, conserved site L21SP4_RS04535 90ce625d0ec17572715d1dec45ed1b32 514 PANTHER PTHR10342 148 506 1.5E-131 T 22-04-2016 L21SP4_RS04535 90ce625d0ec17572715d1dec45ed1b32 514 PANTHER PTHR10342 3 123 1.5E-131 T 22-04-2016 L21SP4_RS04535 90ce625d0ec17572715d1dec45ed1b32 514 PANTHER PTHR10342:SF199 148 506 1.5E-131 T 22-04-2016 L21SP4_RS04535 90ce625d0ec17572715d1dec45ed1b32 514 PANTHER PTHR10342:SF199 3 123 1.5E-131 T 22-04-2016 L21SP4_RS04535 90ce625d0ec17572715d1dec45ed1b32 514 Gene3D G3DSA:3.30.1120.10 417 485 1.8E-12 T 22-04-2016 L21SP4_RS04535 90ce625d0ec17572715d1dec45ed1b32 514 Gene3D G3DSA:3.40.720.10 12 416 9.5E-103 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS04535 90ce625d0ec17572715d1dec45ed1b32 514 ProSitePatterns PS00149 Sulfatases signature 2. 110 120 - T 22-04-2016 IPR024607 Sulfatase, conserved site L21SP4_RS04535 90ce625d0ec17572715d1dec45ed1b32 514 SUPERFAMILY SSF53649 12 126 4.22E-114 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS04535 90ce625d0ec17572715d1dec45ed1b32 514 SUPERFAMILY SSF53649 158 487 4.22E-114 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS04535 90ce625d0ec17572715d1dec45ed1b32 514 Pfam PF00884 Sulfatase 14 374 2.4E-63 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS04085 134046a49045e147250b0da81196f8fd 135 PANTHER PTHR30558:SF3 7 135 4.7E-28 T 22-04-2016 L21SP4_RS04085 134046a49045e147250b0da81196f8fd 135 PANTHER PTHR30558 7 135 4.7E-28 T 22-04-2016 L21SP4_RS04085 134046a49045e147250b0da81196f8fd 135 Pfam PF02472 Biopolymer transport protein ExbD/TolR 7 132 3.1E-27 T 22-04-2016 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 L21SP4_RS10790 89c52135845cdb3d06e75d5fa08fe7c9 323 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 299 320 0.0022 T 22-04-2016 IPR013424 PEP-CTERM protein-sorting domain L21SP4_RS10790 89c52135845cdb3d06e75d5fa08fe7c9 323 Gene3D G3DSA:2.160.20.20 11 286 1.8E-4 T 22-04-2016 IPR012332 P22 tailspike C-terminal domain-like L21SP4_RS10110 1888048ada39bff9767b710a20d2e288 341 PANTHER PTHR34184:SF4 1 287 3.5E-64 T 22-04-2016 L21SP4_RS10110 1888048ada39bff9767b710a20d2e288 341 PANTHER PTHR34184 1 287 3.5E-64 T 22-04-2016 L21SP4_RS10110 1888048ada39bff9767b710a20d2e288 341 Pfam PF03773 Predicted permease 5 284 8.2E-38 T 22-04-2016 IPR005524 Predicted permease DUF318 L21SP4_RS00945 56b7ab71b796686e42eb4d6a7545844c 513 PANTHER PTHR30250:SF0 6 512 3.2E-23 T 22-04-2016 L21SP4_RS00945 56b7ab71b796686e42eb4d6a7545844c 513 Pfam PF13440 Polysaccharide biosynthesis protein 228 319 3.1E-7 T 22-04-2016 L21SP4_RS00945 56b7ab71b796686e42eb4d6a7545844c 513 PANTHER PTHR30250 6 512 3.2E-23 T 22-04-2016 L21SP4_RS00945 56b7ab71b796686e42eb4d6a7545844c 513 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 352 490 2.9E-9 T 22-04-2016 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain L21SP4_RS07335 9272559b801537f000b3e8a6864a3980 264 ProSitePatterns PS01090 TatD deoxyribonuclease family signature 2. 129 139 - T 22-04-2016 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 L21SP4_RS07335 9272559b801537f000b3e8a6864a3980 264 SUPERFAMILY SSF51556 7 262 8.79E-65 T 22-04-2016 IPR032466 Metal-dependent hydrolase L21SP4_RS07335 9272559b801537f000b3e8a6864a3980 264 Gene3D G3DSA:3.20.20.140 4 262 4.4E-67 T 22-04-2016 L21SP4_RS07335 9272559b801537f000b3e8a6864a3980 264 Pfam PF01026 TatD related DNase 8 260 8.2E-61 T 22-04-2016 IPR001130 TatD family GO:0016788 L21SP4_RS07335 9272559b801537f000b3e8a6864a3980 264 PANTHER PTHR10060 1 264 2.7E-74 T 22-04-2016 IPR001130 TatD family GO:0016788 L21SP4_RS07335 9272559b801537f000b3e8a6864a3980 264 PIRSF PIRSF005902 1 264 2.4E-49 T 22-04-2016 IPR001130 TatD family GO:0016788 L21SP4_RS07665 4b62ee7c659aef275006cd0f474b70bf 387 Gene3D G3DSA:2.40.50.100 172 192 1.5E-11 T 22-04-2016 L21SP4_RS07665 4b62ee7c659aef275006cd0f474b70bf 387 Gene3D G3DSA:2.40.50.100 71 98 1.5E-11 T 22-04-2016 L21SP4_RS07665 4b62ee7c659aef275006cd0f474b70bf 387 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 71 378 8.5E-48 T 22-04-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 L21SP4_RS07665 4b62ee7c659aef275006cd0f474b70bf 387 SUPERFAMILY SSF111369 67 287 1.96E-18 T 22-04-2016 L21SP4_RS07665 4b62ee7c659aef275006cd0f474b70bf 387 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 71 282 4.5E-16 T 22-04-2016 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain L21SP4_RS07665 4b62ee7c659aef275006cd0f474b70bf 387 PANTHER PTHR30469 72 387 9.6E-43 T 22-04-2016 L21SP4_RS10135 b00e901045251725379d1054bce9db75 92 Pfam PF04023 FeoA domain 24 89 1.1E-9 T 22-04-2016 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 L21SP4_RS10135 b00e901045251725379d1054bce9db75 92 SUPERFAMILY SSF50037 27 89 1.04E-6 T 22-04-2016 IPR008988 Transcriptional repressor, C-terminal L21SP4_RS10135 b00e901045251725379d1054bce9db75 92 SMART SM00899 23 90 1.9E-5 T 22-04-2016 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 L21SP4_RS07175 88ceb5b6446658156abf874dbbf4bdbc 400 SUPERFAMILY SSF51735 7 190 4.86E-16 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS07175 88ceb5b6446658156abf874dbbf4bdbc 400 Gene3D G3DSA:3.40.50.720 7 189 7.1E-30 T 22-04-2016 IPR016040 NAD(P)-binding domain L21SP4_RS07175 88ceb5b6446658156abf874dbbf4bdbc 400 PANTHER PTHR12286:SF6 1 397 1.8E-159 T 22-04-2016 L21SP4_RS07175 88ceb5b6446658156abf874dbbf4bdbc 400 PANTHER PTHR12286 1 397 1.8E-159 T 22-04-2016 L21SP4_RS07175 88ceb5b6446658156abf874dbbf4bdbc 400 Pfam PF16653 Saccharopine dehydrogenase C-terminal domain 140 388 1.2E-33 T 22-04-2016 IPR032095 Saccharopine dehydrogenase, C-terminal L21SP4_RS07175 88ceb5b6446658156abf874dbbf4bdbc 400 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 7 136 4.2E-32 T 22-04-2016 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 L21SP4_RS02285 6df738e495686f303e4f9e0cad614bdd 280 Pfam PF03799 Cell division protein FtsQ 150 268 2.9E-6 T 22-04-2016 IPR005548 Cell division protein FtsQ/DivIB L21SP4_RS02285 6df738e495686f303e4f9e0cad614bdd 280 Pfam PF08478 POTRA domain, FtsQ-type 65 133 1.0E-9 T 22-04-2016 IPR013685 Polypeptide-transport-associated, FtsQ-type L21SP4_RS00800 f03efa7556aee51dd92e2e315f15d270 407 PIRSF PIRSF033563 1 407 1.1E-107 T 22-04-2016 IPR008323 Uncharacterised conserved protein UCP033563 L21SP4_RS00800 f03efa7556aee51dd92e2e315f15d270 407 Pfam PF06245 Protein of unknown function (DUF1015) 3 403 1.9E-114 T 22-04-2016 IPR008323 Uncharacterised conserved protein UCP033563 L21SP4_RS00800 f03efa7556aee51dd92e2e315f15d270 407 PANTHER PTHR36454 1 407 1.2E-111 T 22-04-2016 L21SP4_RS00800 f03efa7556aee51dd92e2e315f15d270 407 PANTHER PTHR36454:SF1 1 407 1.2E-111 T 22-04-2016 L21SP4_RS08135 650f47c9f8b547aa69dc0cc8690a88dc 106 PANTHER PTHR23426 32 104 8.3E-16 T 22-04-2016 L21SP4_RS08135 650f47c9f8b547aa69dc0cc8690a88dc 106 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 29 97 3.7E-13 T 22-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 L21SP4_RS08135 650f47c9f8b547aa69dc0cc8690a88dc 106 Gene3D G3DSA:3.10.20.30 4 105 3.5E-22 T 22-04-2016 IPR012675 Beta-grasp domain L21SP4_RS08135 650f47c9f8b547aa69dc0cc8690a88dc 106 SUPERFAMILY SSF54292 29 104 2.81E-22 T 22-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 L21SP4_RS08590 86064f64571755b458e7e4d3880cc1a0 498 Pfam PF06253 Trimethylamine methyltransferase (MTTB) 20 429 3.7E-68 T 22-04-2016 IPR010426 Trimethylamine methyltransferase GO:0008168|GO:0015948 KEGG: 00680+2.1.1.250|MetaCyc: PWY-5250|UniPathway: UPA00645 L21SP4_RS05320 b3e08bede6dce810611da7c5dd69e9b8 153 Gene3D G3DSA:1.10.10.10 15 94 1.7E-17 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS05320 b3e08bede6dce810611da7c5dd69e9b8 153 SUPERFAMILY SSF46785 16 148 3.41E-27 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS05320 b3e08bede6dce810611da7c5dd69e9b8 153 Pfam PF01475 Ferric uptake regulator family 25 138 2.8E-20 T 22-04-2016 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 L21SP4_RS05320 b3e08bede6dce810611da7c5dd69e9b8 153 PANTHER PTHR33202 6 152 2.1E-29 T 22-04-2016 L21SP4_RS07855 9d7dfa684aa03e25648bef28a38bd9f7 125 Pfam PF09633 Protein of unknown function (DUF2023) 2 102 1.7E-41 T 22-04-2016 IPR018594 Domain of unknown function DUF2023 L21SP4_RS07855 9d7dfa684aa03e25648bef28a38bd9f7 125 Gene3D G3DSA:3.30.2190.10 1 104 8.4E-44 T 22-04-2016 IPR018594 Domain of unknown function DUF2023 L21SP4_RS07855 9d7dfa684aa03e25648bef28a38bd9f7 125 SUPERFAMILY SSF160448 1 102 9.94E-41 T 22-04-2016 IPR018594 Domain of unknown function DUF2023 L21SP4_RS04390 c69806b0c3ea218f96cdd2092c9d4943 476 SUPERFAMILY SSF75005 259 391 2.49E-12 T 22-04-2016 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP4_RS04390 c69806b0c3ea218f96cdd2092c9d4943 476 Gene3D G3DSA:2.115.10.20 256 391 1.6E-8 T 22-04-2016 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP4_RS05520 381e089b4ac85b1019f7c7f2c018dd4a 347 Pfam PF04338 Protein of unknown function, DUF481 141 346 2.9E-34 T 22-04-2016 IPR007433 Protein of unknown function DUF481 L21SP4_RS02795 7cad8f63b39193f375f87ae865a8af3b 334 SUPERFAMILY SSF46785 7 81 1.21E-5 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS02795 7cad8f63b39193f375f87ae865a8af3b 334 Pfam PF01995 Domain of unknown function DUF128 83 322 1.8E-74 T 22-04-2016 IPR002846 Domain of unknown function DUF128 L21SP4_RS02795 7cad8f63b39193f375f87ae865a8af3b 334 Gene3D G3DSA:3.30.70.1360 169 294 2.9E-35 T 22-04-2016 IPR002846 Domain of unknown function DUF128 L21SP4_RS02795 7cad8f63b39193f375f87ae865a8af3b 334 Pfam PF08461 Ribonuclease R winged-helix domain 10 73 5.3E-16 T 22-04-2016 IPR013668 Ribonuclease R winged-helix domain L21SP4_RS02795 7cad8f63b39193f375f87ae865a8af3b 334 PANTHER PTHR41964 1 332 3.2E-87 T 22-04-2016 L21SP4_RS02795 7cad8f63b39193f375f87ae865a8af3b 334 Gene3D G3DSA:1.10.10.10 35 76 7.0E-4 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS11640 4131137476136eb7d84777c4ff0f2e70 496 SUPERFAMILY SSF53649 1 482 5.89E-115 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS11640 4131137476136eb7d84777c4ff0f2e70 496 Gene3D G3DSA:3.40.720.10 1 412 5.9E-92 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS11640 4131137476136eb7d84777c4ff0f2e70 496 Gene3D G3DSA:3.30.1120.10 417 488 9.6E-16 T 22-04-2016 L21SP4_RS11640 4131137476136eb7d84777c4ff0f2e70 496 Pfam PF00884 Sulfatase 1 385 3.7E-60 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS11640 4131137476136eb7d84777c4ff0f2e70 496 PANTHER PTHR10342 1 196 2.6E-113 T 22-04-2016 L21SP4_RS11640 4131137476136eb7d84777c4ff0f2e70 496 PANTHER PTHR10342 331 481 2.6E-113 T 22-04-2016 L21SP4_RS11640 4131137476136eb7d84777c4ff0f2e70 496 PANTHER PTHR10342 249 303 2.6E-113 T 22-04-2016 L21SP4_RS11640 4131137476136eb7d84777c4ff0f2e70 496 PANTHER PTHR10342:SF199 1 196 2.6E-113 T 22-04-2016 L21SP4_RS11640 4131137476136eb7d84777c4ff0f2e70 496 PANTHER PTHR10342:SF199 331 481 2.6E-113 T 22-04-2016 L21SP4_RS11640 4131137476136eb7d84777c4ff0f2e70 496 PANTHER PTHR10342:SF199 249 303 2.6E-113 T 22-04-2016 L21SP4_RS09530 d32905bd25a6459c90b635d86ed9281b 293 SUPERFAMILY SSF56529 65 282 4.71E-66 T 22-04-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 L21SP4_RS09530 d32905bd25a6459c90b635d86ed9281b 293 Gene3D G3DSA:3.90.850.10 69 284 4.7E-73 T 22-04-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 L21SP4_RS09530 d32905bd25a6459c90b635d86ed9281b 293 PANTHER PTHR11820 1 280 4.9E-87 T 22-04-2016 L21SP4_RS09530 d32905bd25a6459c90b635d86ed9281b 293 PANTHER PTHR11820:SF6 1 280 4.9E-87 T 22-04-2016 L21SP4_RS09530 d32905bd25a6459c90b635d86ed9281b 293 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 77 281 1.2E-59 T 22-04-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 L21SP4_RS03190 7d6f412c9d4068f70e65d1ea77876b80 143 Gene3D G3DSA:3.40.50.1010 1 135 1.0E-5 T 22-04-2016 IPR029060 PIN domain-like L21SP4_RS03190 7d6f412c9d4068f70e65d1ea77876b80 143 Pfam PF01850 PIN domain 2 133 1.1E-18 T 22-04-2016 IPR002716 PIN domain L21SP4_RS03190 7d6f412c9d4068f70e65d1ea77876b80 143 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 139 14.401 T 22-04-2016 IPR022907 VapC family GO:0004540 L21SP4_RS03190 7d6f412c9d4068f70e65d1ea77876b80 143 TIGRFAM TIGR00028 Mtu_PIN_fam: toxin-antitoxin system PIN domain toxin 1 142 3.8E-40 T 22-04-2016 IPR006226 PIN domain toxin GO:0016788 L21SP4_RS03190 7d6f412c9d4068f70e65d1ea77876b80 143 SUPERFAMILY SSF88723 1 140 1.49E-22 T 22-04-2016 IPR029060 PIN domain-like L21SP4_RS06300 60a4a77954696c168ac1d9f82a05a7c3 91 Gene3D G3DSA:3.30.70.330 2 86 1.2E-32 T 22-04-2016 IPR012677 Nucleotide-binding alpha-beta plait domain GO:0000166 L21SP4_RS06300 60a4a77954696c168ac1d9f82a05a7c3 91 Pfam PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 3 73 9.4E-25 T 22-04-2016 IPR000504 RNA recognition motif domain GO:0003676 L21SP4_RS06300 60a4a77954696c168ac1d9f82a05a7c3 91 SUPERFAMILY SSF54928 2 88 1.09E-33 T 22-04-2016 IPR012677 Nucleotide-binding alpha-beta plait domain GO:0000166 L21SP4_RS06300 60a4a77954696c168ac1d9f82a05a7c3 91 SMART SM00360 2 75 8.8E-31 T 22-04-2016 IPR000504 RNA recognition motif domain GO:0003676 L21SP4_RS06300 60a4a77954696c168ac1d9f82a05a7c3 91 PANTHER PTHR24012 2 91 1.5E-31 T 22-04-2016 L21SP4_RS08225 5beef3522b2b83aa6f77d8b470bf9243 348 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 144 337 2.2E-18 T 22-04-2016 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 L21SP4_RS08225 5beef3522b2b83aa6f77d8b470bf9243 348 Gene3D G3DSA:3.20.20.210 95 337 2.1E-25 T 22-04-2016 L21SP4_RS08225 5beef3522b2b83aa6f77d8b470bf9243 348 SUPERFAMILY SSF51726 49 338 6.28E-25 T 22-04-2016 L21SP4_RS05270 5db77f1bb13237d5b72caa9df2483bc3 135 TIGRFAM TIGR04138 Plancto_Ver_chp: Verruc_Plancto-restricted protein 10 128 3.1E-46 T 22-04-2016 IPR026406 Verrucomicrobia /Planctomycetes-restricted protein L21SP4_RS01210 555cd719b81ae1429cb808b91cdcbb89 489 Pfam PF09822 ABC-type uncharacterized transport system 45 294 9.3E-30 T 22-04-2016 IPR019196 ABC-type uncharacterised transport system L21SP4_RS12125 0c6e621898f66ea87c13478ec080b156 358 Gene3D G3DSA:3.20.20.80 27 312 2.1E-33 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP4_RS12125 0c6e621898f66ea87c13478ec080b156 358 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 69 276 8.3E-13 T 22-04-2016 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 L21SP4_RS12125 0c6e621898f66ea87c13478ec080b156 358 SUPERFAMILY SSF51445 35 298 2.04E-35 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily L21SP4_RS10655 3a57b30b2706e774d10d2786533ee4b2 274 Pfam PF06230 Protein of unknown function (DUF1009) 68 272 9.7E-66 T 22-04-2016 IPR010415 Protein of unknown function DUF1009 L21SP4_RS10655 3a57b30b2706e774d10d2786533ee4b2 274 PANTHER PTHR39962 7 272 7.8E-58 T 22-04-2016 L21SP4_RS10655 3a57b30b2706e774d10d2786533ee4b2 274 PANTHER PTHR39962:SF1 7 272 7.8E-58 T 22-04-2016 L21SP4_RS07690 47729f1432c27c7c16a5c6a19df93e77 383 SUPERFAMILY SSF56954 6 376 1.57E-46 T 22-04-2016 L21SP4_RS07690 47729f1432c27c7c16a5c6a19df93e77 383 PANTHER PTHR30203 3 373 2.5E-24 T 22-04-2016 L21SP4_RS07690 47729f1432c27c7c16a5c6a19df93e77 383 Pfam PF02321 Outer membrane efflux protein 190 350 2.3E-19 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 L21SP4_RS07690 47729f1432c27c7c16a5c6a19df93e77 383 Pfam PF02321 Outer membrane efflux protein 7 165 2.3E-10 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 L21SP4_RS07690 47729f1432c27c7c16a5c6a19df93e77 383 Gene3D G3DSA:1.20.1600.10 7 377 5.8E-43 T 22-04-2016 L21SP4_RS04395 df22cf35eca56cdd7e046c41c85122e0 362 Gene3D G3DSA:3.20.20.210 118 300 3.1E-5 T 22-04-2016 L21SP4_RS04395 df22cf35eca56cdd7e046c41c85122e0 362 SUPERFAMILY SSF51726 80 331 4.19E-7 T 22-04-2016 L21SP4_RS01655 700c32f5bd7e0315b4a970479272d001 337 PANTHER PTHR11938 26 328 2.1E-62 T 22-04-2016 L21SP4_RS01655 700c32f5bd7e0315b4a970479272d001 337 PANTHER PTHR11938:SF103 26 328 2.1E-62 T 22-04-2016 L21SP4_RS01655 700c32f5bd7e0315b4a970479272d001 337 Pfam PF01180 Dihydroorotate dehydrogenase 85 276 1.5E-12 T 22-04-2016 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 L21SP4_RS01655 700c32f5bd7e0315b4a970479272d001 337 PIRSF PIRSF000164 1 307 1.9E-44 T 22-04-2016 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 Reactome: REACT_1698 L21SP4_RS01655 700c32f5bd7e0315b4a970479272d001 337 Gene3D G3DSA:3.20.20.70 4 295 3.3E-54 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP4_RS01655 700c32f5bd7e0315b4a970479272d001 337 SUPERFAMILY SSF51395 2 306 5.66E-60 T 22-04-2016 L21SP4_RS11965 7338581dc4a7da86b4a193468454b578 221 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 206 7.5E-19 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 L21SP4_RS11965 7338581dc4a7da86b4a193468454b578 221 Gene3D G3DSA:1.10.3720.10 8 196 1.0E-28 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 L21SP4_RS11965 7338581dc4a7da86b4a193468454b578 221 PANTHER PTHR30177 1 214 8.6E-80 T 22-04-2016 L21SP4_RS11965 7338581dc4a7da86b4a193468454b578 221 SUPERFAMILY SSF161098 14 195 3.14E-36 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 L21SP4_RS11965 7338581dc4a7da86b4a193468454b578 221 PANTHER PTHR30177:SF4 1 214 8.6E-80 T 22-04-2016 L21SP4_RS01585 b03c024414e5035fa3ea298aec4307f4 590 Gene3D G3DSA:2.160.20.10 21 112 1.6E-13 T 22-04-2016 IPR012334 Pectin lyase fold L21SP4_RS01585 b03c024414e5035fa3ea298aec4307f4 590 Gene3D G3DSA:2.160.20.10 273 358 1.6E-13 T 22-04-2016 IPR012334 Pectin lyase fold L21SP4_RS01585 b03c024414e5035fa3ea298aec4307f4 590 Gene3D G3DSA:2.160.20.10 151 182 1.6E-13 T 22-04-2016 IPR012334 Pectin lyase fold L21SP4_RS01585 b03c024414e5035fa3ea298aec4307f4 590 SUPERFAMILY SSF51126 20 358 3.77E-21 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor L21SP4_RS08795 61348f74ca77334a9c114f4721ef446a 276 PANTHER PTHR22916 1 245 1.7E-34 T 22-04-2016 L21SP4_RS08795 61348f74ca77334a9c114f4721ef446a 276 SUPERFAMILY SSF53448 7 228 6.57E-43 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases L21SP4_RS08795 61348f74ca77334a9c114f4721ef446a 276 Gene3D G3DSA:3.90.550.10 10 225 2.7E-32 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases L21SP4_RS08795 61348f74ca77334a9c114f4721ef446a 276 Pfam PF00535 Glycosyl transferase family 2 15 128 8.3E-20 T 22-04-2016 IPR001173 Glycosyltransferase 2-like L21SP4_RS04065 df0d646a0f443e60c41be7bd7618159a 277 SUPERFAMILY SSF54506 130 267 3.14E-32 T 22-04-2016 L21SP4_RS04065 df0d646a0f443e60c41be7bd7618159a 277 PANTHER PTHR31689 1 273 3.6E-78 T 22-04-2016 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097|UniPathway: UPA00034 L21SP4_RS04065 df0d646a0f443e60c41be7bd7618159a 277 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 3 269 31.727 T 22-04-2016 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097|UniPathway: UPA00034 L21SP4_RS04065 df0d646a0f443e60c41be7bd7618159a 277 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 3 266 1.3E-70 T 22-04-2016 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097|UniPathway: UPA00034 L21SP4_RS04065 df0d646a0f443e60c41be7bd7618159a 277 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 65 79 - T 22-04-2016 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097|UniPathway: UPA00034 L21SP4_RS04065 df0d646a0f443e60c41be7bd7618159a 277 Pfam PF01678 Diaminopimelate epimerase 142 261 9.5E-16 T 22-04-2016 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097|UniPathway: UPA00034 L21SP4_RS04065 df0d646a0f443e60c41be7bd7618159a 277 Pfam PF01678 Diaminopimelate epimerase 5 121 2.6E-28 T 22-04-2016 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097|UniPathway: UPA00034 L21SP4_RS04065 df0d646a0f443e60c41be7bd7618159a 277 SUPERFAMILY SSF54506 3 123 6.98E-38 T 22-04-2016 L21SP4_RS04065 df0d646a0f443e60c41be7bd7618159a 277 Gene3D G3DSA:3.10.310.10 142 245 1.2E-30 T 22-04-2016 L21SP4_RS04065 df0d646a0f443e60c41be7bd7618159a 277 Gene3D G3DSA:3.10.310.10 1 141 3.2E-46 T 22-04-2016 L21SP4_RS12160 594bc2ec1c2d0bbb6aa587969434dd63 313 Pfam PF00005 ABC transporter 18 160 1.7E-31 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 L21SP4_RS12160 594bc2ec1c2d0bbb6aa587969434dd63 313 SMART SM00382 26 216 1.2E-14 T 22-04-2016 IPR003593 AAA+ ATPase domain L21SP4_RS12160 594bc2ec1c2d0bbb6aa587969434dd63 313 PANTHER PTHR24220 3 216 1.6E-84 T 22-04-2016 L21SP4_RS12160 594bc2ec1c2d0bbb6aa587969434dd63 313 Gene3D G3DSA:3.40.50.300 1 225 5.8E-67 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS12160 594bc2ec1c2d0bbb6aa587969434dd63 313 SUPERFAMILY SSF52540 2 220 1.52E-61 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS03760 c4856ba6c6fd2ffacc95a1fa9e1fc75e 143 Gene3D G3DSA:1.10.10.10 8 140 3.0E-34 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS03760 c4856ba6c6fd2ffacc95a1fa9e1fc75e 143 SMART SM00347 29 129 5.0E-24 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 L21SP4_RS03760 c4856ba6c6fd2ffacc95a1fa9e1fc75e 143 SUPERFAMILY SSF46785 6 140 3.12E-31 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS03760 c4856ba6c6fd2ffacc95a1fa9e1fc75e 143 PANTHER PTHR33164 3 142 6.6E-25 T 22-04-2016 L21SP4_RS03760 c4856ba6c6fd2ffacc95a1fa9e1fc75e 143 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 85 3.28E-8 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 L21SP4_RS03760 c4856ba6c6fd2ffacc95a1fa9e1fc75e 143 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 105 3.28E-8 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 L21SP4_RS03760 c4856ba6c6fd2ffacc95a1fa9e1fc75e 143 PRINTS PR00598 Bacterial regulatory protein MarR family signature 119 139 3.28E-8 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 L21SP4_RS03760 c4856ba6c6fd2ffacc95a1fa9e1fc75e 143 Pfam PF01047 MarR family 36 94 6.3E-13 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 L21SP4_RS08170 62f9f5628410486d078eacbc3ab1ad81 362 Pfam PF13480 Acetyltransferase (GNAT) domain 167 288 6.8E-5 T 22-04-2016 L21SP4_RS08170 62f9f5628410486d078eacbc3ab1ad81 362 SUPERFAMILY SSF55729 160 332 1.14E-11 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase L21SP4_RS11695 13c9e671a8c57100eb51db30cfa66a46 78 Pfam PF04986 Putative transposase 7 57 4.8E-9 T 22-04-2016 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 L21SP4_RS05850 11f07109142fc8d395be8ad7f83579d5 342 Gene3D G3DSA:3.40.50.2000 159 306 6.7E-30 T 22-04-2016 L21SP4_RS05850 11f07109142fc8d395be8ad7f83579d5 342 SUPERFAMILY SSF53756 5 335 6.81E-71 T 22-04-2016 L21SP4_RS05850 11f07109142fc8d395be8ad7f83579d5 342 Pfam PF00534 Glycosyl transferases group 1 160 309 2.3E-35 T 22-04-2016 IPR001296 Glycosyl transferase, family 1 L21SP4_RS05850 11f07109142fc8d395be8ad7f83579d5 342 PANTHER PTHR12526 5 335 6.5E-49 T 22-04-2016 L21SP4_RS05850 11f07109142fc8d395be8ad7f83579d5 342 Pfam PF13439 Glycosyltransferase Family 4 6 145 3.2E-14 T 22-04-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain L21SP4_RS01200 0c28be4dfdc50b3feb7bb934456ccea2 937 Pfam PF13502 AsmA-like C-terminal region 709 899 2.7E-6 T 22-04-2016 IPR032712 AsmA-like, C-terminal L21SP4_RS09355 2d322eb8d96a28bc2463cbca25879c3e 274 PANTHER PTHR22726 5 268 2.3E-53 T 22-04-2016 L21SP4_RS09355 2d322eb8d96a28bc2463cbca25879c3e 274 Pfam PF01435 Peptidase family M48 71 258 5.0E-39 T 22-04-2016 IPR001915 Peptidase M48 GO:0004222|GO:0006508 L21SP4_RS09355 2d322eb8d96a28bc2463cbca25879c3e 274 Gene3D G3DSA:3.30.2010.10 66 152 9.5E-18 T 22-04-2016 L21SP4_RS09445 1a10a1ead16640e19bdc425f904c52a4 377 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 164 376 3.5E-15 T 22-04-2016 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 L21SP4_RS09445 1a10a1ead16640e19bdc425f904c52a4 377 Gene3D G3DSA:3.20.20.210 165 376 1.3E-19 T 22-04-2016 L21SP4_RS09445 1a10a1ead16640e19bdc425f904c52a4 377 Gene3D G3DSA:3.20.20.210 116 128 1.3E-19 T 22-04-2016 L21SP4_RS09445 1a10a1ead16640e19bdc425f904c52a4 377 SUPERFAMILY SSF51726 115 376 6.28E-22 T 22-04-2016 L21SP4_RS04595 97163dd63d39437d4731e9e2c5dea9ff 423 Gene3D G3DSA:3.20.20.210 136 401 1.2E-11 T 22-04-2016 L21SP4_RS04860 34335aab5a7e829c34f672ee396716b0 324 Pfam PF02517 CAAX protease self-immunity 135 239 4.8E-12 T 22-04-2016 IPR003675 CAAX amino terminal protease GO:0016020 L21SP4_RS07905 4a6206621331143ea698327d6a4eeb45 644 SMART SM01080 28 347 1.4E-52 T 22-04-2016 IPR007890 CHASE2 L21SP4_RS07905 4a6206621331143ea698327d6a4eeb45 644 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 445 621 5.2E-30 T 22-04-2016 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 L21SP4_RS07905 4a6206621331143ea698327d6a4eeb45 644 SMART SM00044 409 615 9.8E-21 T 22-04-2016 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 L21SP4_RS07905 4a6206621331143ea698327d6a4eeb45 644 SUPERFAMILY SSF55073 439 626 2.83E-57 T 22-04-2016 IPR029787 Nucleotide cyclase L21SP4_RS07905 4a6206621331143ea698327d6a4eeb45 644 Pfam PF05226 CHASE2 domain 18 341 4.6E-53 T 22-04-2016 IPR007890 CHASE2 L21SP4_RS07905 4a6206621331143ea698327d6a4eeb45 644 Gene3D G3DSA:3.30.70.1230 443 625 1.1E-47 T 22-04-2016 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 L21SP4_RS07905 4a6206621331143ea698327d6a4eeb45 644 PANTHER PTHR11920:SF341 388 643 5.8E-57 T 22-04-2016 L21SP4_RS07905 4a6206621331143ea698327d6a4eeb45 644 PANTHER PTHR11920 388 643 5.8E-57 T 22-04-2016 L21SP4_RS02515 b047a6d9558076fdbbc5e581655facd6 232 Gene3D G3DSA:3.20.20.70 12 142 1.7E-12 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP4_RS02515 b047a6d9558076fdbbc5e581655facd6 232 PANTHER PTHR11228 1 196 4.7E-30 T 22-04-2016 L21SP4_RS02515 b047a6d9558076fdbbc5e581655facd6 232 SUPERFAMILY SSF102114 12 123 6.67E-10 T 22-04-2016 L21SP4_RS02515 b047a6d9558076fdbbc5e581655facd6 232 PANTHER PTHR11228:SF19 1 196 4.7E-30 T 22-04-2016 L21SP4_RS03935 d386675e74395b5e5de4f5a881a9cf60 272 Pfam PF02811 PHP domain 7 192 3.0E-7 T 22-04-2016 IPR004013 PHP domain GO:0003824 L21SP4_RS03935 d386675e74395b5e5de4f5a881a9cf60 272 Gene3D G3DSA:3.20.20.140 6 252 3.8E-34 T 22-04-2016 L21SP4_RS03935 d386675e74395b5e5de4f5a881a9cf60 272 PANTHER PTHR21039 5 271 5.0E-57 T 22-04-2016 IPR010140 Histidinol phosphate phosphatase, HisJ GO:0000105|GO:0004401 KEGG: 00340+3.1.3.15|UniPathway: UPA00031 L21SP4_RS03935 d386675e74395b5e5de4f5a881a9cf60 272 TIGRFAM TIGR01856 hisJ_fam: histidinol phosphate phosphatase, HisJ family 7 236 3.4E-38 T 22-04-2016 IPR010140 Histidinol phosphate phosphatase, HisJ GO:0000105|GO:0004401 KEGG: 00340+3.1.3.15|UniPathway: UPA00031 L21SP4_RS03935 d386675e74395b5e5de4f5a881a9cf60 272 SUPERFAMILY SSF89550 5 256 1.96E-41 T 22-04-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 L21SP4_RS05145 c8b4d28fcaf27a48cf2a0ec395e4f2ff 92 Gene3D G3DSA:3.30.70.100 4 91 2.2E-26 T 22-04-2016 L21SP4_RS05145 c8b4d28fcaf27a48cf2a0ec395e4f2ff 92 SUPERFAMILY SSF54975 4 91 1.42E-24 T 22-04-2016 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 L21SP4_RS05145 c8b4d28fcaf27a48cf2a0ec395e4f2ff 92 ProSitePatterns PS00151 Acylphosphatase signature 2. 34 50 - T 22-04-2016 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 L21SP4_RS05145 c8b4d28fcaf27a48cf2a0ec395e4f2ff 92 Pfam PF00708 Acylphosphatase 4 91 1.8E-23 T 22-04-2016 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 L21SP4_RS05145 c8b4d28fcaf27a48cf2a0ec395e4f2ff 92 PRINTS PR00112 Acylphosphatase signature 5 20 4.1E-6 T 22-04-2016 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 L21SP4_RS05145 c8b4d28fcaf27a48cf2a0ec395e4f2ff 92 PRINTS PR00112 Acylphosphatase signature 26 51 4.1E-6 T 22-04-2016 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 L21SP4_RS05145 c8b4d28fcaf27a48cf2a0ec395e4f2ff 92 PANTHER PTHR10029 6 92 8.6E-18 T 22-04-2016 L21SP4_RS04810 a2315da96f0740f181f261dd079b91fd 121 Pfam PF10825 Protein of unknown function (DUF2752) 30 74 5.4E-11 T 22-04-2016 IPR021215 Protein of unknown function DUF2752 L21SP4_RS11205 1f0e2a1f0188e2a41688fde60c2f376b 345 SUPERFAMILY SSF53756 1 328 1.38E-18 T 22-04-2016 L21SP4_RS11205 1f0e2a1f0188e2a41688fde60c2f376b 345 Pfam PF04007 Protein of unknown function (DUF354) 1 298 1.1E-36 T 22-04-2016 IPR007152 Protein of unknown function DUF354 L21SP4_RS11205 1f0e2a1f0188e2a41688fde60c2f376b 345 PANTHER PTHR39662 2 345 1.2E-46 T 22-04-2016 L21SP4_RS11205 1f0e2a1f0188e2a41688fde60c2f376b 345 PIRSF PIRSF005357 1 311 4.2E-54 T 22-04-2016 IPR007152 Protein of unknown function DUF354 L21SP4_RS11205 1f0e2a1f0188e2a41688fde60c2f376b 345 PANTHER PTHR39662:SF1 2 345 1.2E-46 T 22-04-2016 L21SP4_RS04870 e55407cdda396d7f7d6138f2fc7310d9 1065 Pfam PF00176 SNF2 family N-terminal domain 612 885 3.8E-61 T 22-04-2016 IPR000330 SNF2-related, N-terminal domain GO:0005524 L21SP4_RS04870 e55407cdda396d7f7d6138f2fc7310d9 1065 Gene3D G3DSA:3.40.50.300 592 769 6.7E-29 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS04870 e55407cdda396d7f7d6138f2fc7310d9 1065 SMART SM00487 595 780 5.2E-32 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain L21SP4_RS04870 e55407cdda396d7f7d6138f2fc7310d9 1065 Gene3D G3DSA:3.40.50.300 896 1047 4.7E-20 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS04870 e55407cdda396d7f7d6138f2fc7310d9 1065 SUPERFAMILY SSF52540 815 1064 5.0E-65 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS04870 e55407cdda396d7f7d6138f2fc7310d9 1065 SUPERFAMILY SSF52540 581 813 4.87E-57 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS04870 e55407cdda396d7f7d6138f2fc7310d9 1065 SMART SM00490 928 1009 2.7E-23 T 22-04-2016 IPR001650 Helicase, C-terminal L21SP4_RS04870 e55407cdda396d7f7d6138f2fc7310d9 1065 Pfam PF08455 Bacterial SNF2 helicase associated 272 562 1.3E-11 T 22-04-2016 IPR013663 Helicase, SWF/SNF/SWI type, bacterial L21SP4_RS04870 e55407cdda396d7f7d6138f2fc7310d9 1065 Pfam PF00271 Helicase conserved C-terminal domain 902 1009 6.7E-17 T 22-04-2016 IPR001650 Helicase, C-terminal L21SP4_RS04870 e55407cdda396d7f7d6138f2fc7310d9 1065 PANTHER PTHR10799 582 1052 9.9E-175 T 22-04-2016 L21SP4_RS04625 0f1aec9d152a538e34014e9cc5e0656d 577 Gene3D G3DSA:2.160.20.10 14 98 3.8E-15 T 22-04-2016 IPR012334 Pectin lyase fold L21SP4_RS04625 0f1aec9d152a538e34014e9cc5e0656d 577 Gene3D G3DSA:2.160.20.10 252 374 3.8E-15 T 22-04-2016 IPR012334 Pectin lyase fold L21SP4_RS04625 0f1aec9d152a538e34014e9cc5e0656d 577 Gene3D G3DSA:2.160.20.10 160 199 3.8E-15 T 22-04-2016 IPR012334 Pectin lyase fold L21SP4_RS04625 0f1aec9d152a538e34014e9cc5e0656d 577 SUPERFAMILY SSF51126 172 302 3.88E-15 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor L21SP4_RS04625 0f1aec9d152a538e34014e9cc5e0656d 577 SUPERFAMILY SSF51126 9 101 3.88E-15 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor L21SP4_RS04625 0f1aec9d152a538e34014e9cc5e0656d 577 SUPERFAMILY SSF51126 334 372 3.88E-15 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor L21SP4_RS06340 3796dc81c1a802509cdf0bc91cce8a2c 264 Pfam PF08843 Nucleotidyl transferase AbiEii toxin, Type IV TA system 34 242 8.6E-25 T 22-04-2016 IPR014942 Nucleotidyl transferase AbiEii toxin, Type IV TA system L21SP4_RS02685 3036afc3b6c63c76078df474eab82d8b 298 Gene3D G3DSA:3.40.50.150 28 195 9.2E-14 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS02685 3036afc3b6c63c76078df474eab82d8b 298 Pfam PF08241 Methyltransferase domain 46 137 6.4E-10 T 22-04-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 L21SP4_RS02685 3036afc3b6c63c76078df474eab82d8b 298 SUPERFAMILY SSF53335 22 197 1.09E-16 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS01150 bbc1192ad8c1797f7ef50c0cc715781b 139 Pfam PF02620 Uncharacterized ACR, COG1399 76 137 7.9E-14 T 22-04-2016 IPR003772 Protein of unknown function DUF177 L21SP4_RS08295 81ed01e5eed7f185ff97e5ab6e57b12f 79 Gene3D G3DSA:2.40.50.140 4 71 9.9E-12 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold L21SP4_RS08295 81ed01e5eed7f185ff97e5ab6e57b12f 79 SUPERFAMILY SSF50249 7 71 6.57E-9 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold L21SP4_RS11930 59eac56e87545bb0e00a00dc48348fb6 409 Pfam PF13635 Domain of unknown function (DUF4143) 200 357 2.1E-26 T 22-04-2016 IPR025420 Domain of unknown function DUF4143 L21SP4_RS11930 59eac56e87545bb0e00a00dc48348fb6 409 PANTHER PTHR33295:SF5 1 409 1.5E-130 T 22-04-2016 L21SP4_RS11930 59eac56e87545bb0e00a00dc48348fb6 409 SUPERFAMILY SSF52540 4 188 4.54E-17 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS11930 59eac56e87545bb0e00a00dc48348fb6 409 Gene3D G3DSA:3.40.50.300 3 127 2.1E-11 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS11930 59eac56e87545bb0e00a00dc48348fb6 409 PANTHER PTHR33295 1 409 1.5E-130 T 22-04-2016 L21SP4_RS11930 59eac56e87545bb0e00a00dc48348fb6 409 Pfam PF13173 AAA domain 18 136 4.5E-24 T 22-04-2016 L21SP4_RS05840 661dfd43e90ae7211cc6a1aff98f4dd5 327 Pfam PF06258 Mitochondrial fission ELM1 13 305 4.6E-41 T 22-04-2016 IPR009367 Mitochondrial fission protein ELM1-like L21SP4_RS09825 09f714741311386abbe7ecf3ea8421b0 304 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 8 237 7.9E-26 T 22-04-2016 IPR002729 CRISPR-associated protein Cas1 L21SP4_RS09825 09f714741311386abbe7ecf3ea8421b0 304 PANTHER PTHR34353 1 237 2.3E-41 T 22-04-2016 L21SP4_RS09825 09f714741311386abbe7ecf3ea8421b0 304 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 5 297 15.324 T 22-04-2016 IPR002729 CRISPR-associated protein Cas1 L21SP4_RS09825 09f714741311386abbe7ecf3ea8421b0 304 Pfam PF01867 CRISPR associated protein Cas1 8 235 8.3E-31 T 22-04-2016 IPR002729 CRISPR-associated protein Cas1 L21SP4_RS09825 09f714741311386abbe7ecf3ea8421b0 304 TIGRFAM TIGR03639 cas1_NMENI: CRISPR-associated endonuclease Cas1, subtype II/NMENI 5 281 2.0E-85 T 22-04-2016 IPR019855 CRISPR-associated protein Cas1, NMENI subtype L21SP4_RS04610 b722e8456c9c7ed30aacc3c4706819ac 501 PANTHER PTHR10342 398 454 9.0E-94 T 22-04-2016 L21SP4_RS04610 b722e8456c9c7ed30aacc3c4706819ac 501 PANTHER PTHR10342 1 375 9.0E-94 T 22-04-2016 L21SP4_RS04610 b722e8456c9c7ed30aacc3c4706819ac 501 PANTHER PTHR10342 471 484 9.0E-94 T 22-04-2016 L21SP4_RS04610 b722e8456c9c7ed30aacc3c4706819ac 501 SUPERFAMILY SSF53649 23 463 8.0E-102 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP4_RS04610 b722e8456c9c7ed30aacc3c4706819ac 501 Gene3D G3DSA:3.40.720.10 23 327 2.4E-74 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP4_RS04610 b722e8456c9c7ed30aacc3c4706819ac 501 Gene3D G3DSA:3.30.1120.10 406 457 1.9E-13 T 22-04-2016 L21SP4_RS04610 b722e8456c9c7ed30aacc3c4706819ac 501 Gene3D G3DSA:3.30.1120.10 338 368 1.9E-13 T 22-04-2016 L21SP4_RS04610 b722e8456c9c7ed30aacc3c4706819ac 501 Pfam PF00884 Sulfatase 26 307 4.4E-51 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP4_RS03570 e1af397db1dbf08facd009c765a06e59 185 Gene3D G3DSA:3.30.70.60 82 181 2.6E-9 T 22-04-2016 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 L21SP4_RS01630 9df0faf59f71c65c91123b848d15a608 351 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 119 349 1.7E-27 T 22-04-2016 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 L21SP4_RS01630 9df0faf59f71c65c91123b848d15a608 351 Gene3D G3DSA:3.20.20.210 1 350 5.0E-49 T 22-04-2016 L21SP4_RS01630 9df0faf59f71c65c91123b848d15a608 351 SUPERFAMILY SSF51726 1 350 4.84E-41 T 22-04-2016 L21SP4_RS11865 c0a4249c17c6b74eac6aa045e5500466 172 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 28 158 4.0E-33 T 22-04-2016 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component L21SP4_RS11865 c0a4249c17c6b74eac6aa045e5500466 172 PANTHER PTHR35011 1 172 5.8E-31 T 22-04-2016 L21SP4_RS11755 8e09a9da1d63b906e39145ed83a0bf4c 359 Pfam PF13377 Periplasmic binding protein-like domain 191 354 2.4E-22 T 22-04-2016 L21SP4_RS11755 8e09a9da1d63b906e39145ed83a0bf4c 359 SUPERFAMILY SSF46785 2 66 4.96E-13 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS11755 8e09a9da1d63b906e39145ed83a0bf4c 359 Pfam PF00392 Bacterial regulatory proteins, gntR family 2 62 3.1E-11 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 L21SP4_RS11755 8e09a9da1d63b906e39145ed83a0bf4c 359 Gene3D G3DSA:3.40.50.2300 135 189 2.0E-4 T 22-04-2016 L21SP4_RS11755 8e09a9da1d63b906e39145ed83a0bf4c 359 Gene3D G3DSA:3.40.50.2300 190 354 1.2E-34 T 22-04-2016 L21SP4_RS11755 8e09a9da1d63b906e39145ed83a0bf4c 359 SMART SM00345 5 62 1.5E-7 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 L21SP4_RS11755 8e09a9da1d63b906e39145ed83a0bf4c 359 PANTHER PTHR30146 120 359 1.3E-28 T 22-04-2016 L21SP4_RS11755 8e09a9da1d63b906e39145ed83a0bf4c 359 SUPERFAMILY SSF53822 121 355 7.66E-32 T 22-04-2016 IPR028082 Periplasmic binding protein-like I L21SP4_RS11755 8e09a9da1d63b906e39145ed83a0bf4c 359 Gene3D G3DSA:1.10.10.10 2 68 1.0E-15 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS05530 02ad61bc907992618317c7c8452267dd 400 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 172 398 1.4E-16 T 22-04-2016 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 L21SP4_RS05530 02ad61bc907992618317c7c8452267dd 400 SUPERFAMILY SSF51726 162 399 1.08E-32 T 22-04-2016 L21SP4_RS05530 02ad61bc907992618317c7c8452267dd 400 SUPERFAMILY SSF51726 16 116 1.08E-32 T 22-04-2016 L21SP4_RS05530 02ad61bc907992618317c7c8452267dd 400 Gene3D G3DSA:3.20.20.210 12 128 1.5E-34 T 22-04-2016 L21SP4_RS05530 02ad61bc907992618317c7c8452267dd 400 Gene3D G3DSA:3.20.20.210 165 399 1.5E-34 T 22-04-2016 L21SP4_RS11960 fd17b0cc07103d9591c34b515b2066b2 244 SUPERFAMILY SSF161098 40 225 3.01E-35 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 L21SP4_RS11960 fd17b0cc07103d9591c34b515b2066b2 244 PANTHER PTHR30177 8 241 9.7E-60 T 22-04-2016 L21SP4_RS11960 fd17b0cc07103d9591c34b515b2066b2 244 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 64 224 9.4E-22 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 L21SP4_RS11960 fd17b0cc07103d9591c34b515b2066b2 244 Gene3D G3DSA:1.10.3720.10 40 225 4.3E-28 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 L21SP4_RS11370 9421ef966e40a27be672bf2bbfdfae9e 175 PANTHER PTHR38465 11 153 3.6E-21 T 22-04-2016 L21SP4_RS11370 9421ef966e40a27be672bf2bbfdfae9e 175 Pfam PF01022 Bacterial regulatory protein, arsR family 55 83 3.7E-5 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 L21SP4_RS11370 9421ef966e40a27be672bf2bbfdfae9e 175 PIRSF PIRSF006707 9 175 8.1E-30 T 22-04-2016 IPR026282 DNA-binding protein, MJ1563 type L21SP4_RS11370 9421ef966e40a27be672bf2bbfdfae9e 175 Gene3D G3DSA:1.10.10.10 21 103 1.0E-15 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS11370 9421ef966e40a27be672bf2bbfdfae9e 175 SUPERFAMILY SSF46785 21 157 1.43E-12 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS11240 030eaa726c153aa0605620296f1a8346 384 PANTHER PTHR12526 32 376 6.4E-13 T 22-04-2016 L21SP4_RS11240 030eaa726c153aa0605620296f1a8346 384 SUPERFAMILY SSF53756 26 374 6.0E-33 T 22-04-2016 L21SP4_RS11240 030eaa726c153aa0605620296f1a8346 384 Gene3D G3DSA:3.40.50.2000 202 277 0.001 T 22-04-2016 L21SP4_RS11240 030eaa726c153aa0605620296f1a8346 384 Pfam PF13692 Glycosyl transferases group 1 201 344 8.3E-9 T 22-04-2016 L21SP4_RS11240 030eaa726c153aa0605620296f1a8346 384 Pfam PF13579 Glycosyl transferase 4-like domain 31 178 5.2E-9 T 22-04-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain L21SP4_RS07620 c1e266dc99fd7835e520ec7c61971c2b 252 Pfam PF11932 Protein of unknown function (DUF3450) 4 244 3.5E-17 T 22-04-2016 IPR016866 Uncharacterised conserved protein UCP028069 L21SP4_RS00345 f6bb5e9475a8ede2baf8df6136ba5884 538 Pfam PF06418 CTP synthase N-terminus 3 266 4.5E-119 T 22-04-2016 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: REACT_1698|UniPathway: UPA00159 L21SP4_RS00345 f6bb5e9475a8ede2baf8df6136ba5884 538 Hamap MF_01227 CTP synthase [pyrG]. 2 533 49.448 T 22-04-2016 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: REACT_1698|UniPathway: UPA00159 L21SP4_RS00345 f6bb5e9475a8ede2baf8df6136ba5884 538 Gene3D G3DSA:3.40.50.880 289 532 1.6E-94 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like L21SP4_RS00345 f6bb5e9475a8ede2baf8df6136ba5884 538 PANTHER PTHR11550 1 532 1.0E-302 T 22-04-2016 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: REACT_1698|UniPathway: UPA00159 L21SP4_RS00345 f6bb5e9475a8ede2baf8df6136ba5884 538 SUPERFAMILY SSF52317 290 532 1.48E-76 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like L21SP4_RS00345 f6bb5e9475a8ede2baf8df6136ba5884 538 TIGRFAM TIGR00337 PyrG: CTP synthase 1 528 7.1E-236 T 22-04-2016 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: REACT_1698|UniPathway: UPA00159 L21SP4_RS00345 f6bb5e9475a8ede2baf8df6136ba5884 538 Gene3D G3DSA:3.40.50.300 1 284 4.2E-125 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS00345 f6bb5e9475a8ede2baf8df6136ba5884 538 SUPERFAMILY SSF52540 2 267 1.68E-112 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS00345 f6bb5e9475a8ede2baf8df6136ba5884 538 Pfam PF00117 Glutamine amidotransferase class-I 302 527 2.8E-55 T 22-04-2016 IPR017926 Glutamine amidotransferase Reactome: REACT_1698 L21SP4_RS08180 7ea438c24a77b1d879e82bedb43c22bc 142 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 5 137 1.8E-18 T 22-04-2016 IPR009936 Protein of unknown function DUF1468 L21SP4_RS05870 6322514a546ac41e5a0564862b5c30e6 318 Pfam PF13469 Sulfotransferase family 11 199 8.6E-9 T 22-04-2016 L21SP4_RS05870 6322514a546ac41e5a0564862b5c30e6 318 Gene3D G3DSA:3.40.50.300 10 311 1.8E-14 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS05870 6322514a546ac41e5a0564862b5c30e6 318 SUPERFAMILY SSF52540 100 202 2.08E-19 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS05870 6322514a546ac41e5a0564862b5c30e6 318 SUPERFAMILY SSF52540 7 37 2.08E-19 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS10710 0f4b1b20e7386b9a679376c4dd4afb6d 135 PANTHER PTHR11075 1 127 3.3E-24 T 22-04-2016 L21SP4_RS10710 0f4b1b20e7386b9a679376c4dd4afb6d 135 Pfam PF00472 RF-1 domain 16 127 2.0E-24 T 22-04-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 L21SP4_RS10710 0f4b1b20e7386b9a679376c4dd4afb6d 135 SUPERFAMILY SSF75620 13 110 5.23E-23 T 22-04-2016 L21SP4_RS10710 0f4b1b20e7386b9a679376c4dd4afb6d 135 Gene3D G3DSA:3.30.160.20 16 91 1.8E-26 T 22-04-2016 IPR014720 Double-stranded RNA-binding domain L21SP4_RS00815 508566e7566e50af3fd973002d17759b 418 PANTHER PTHR32507:SF10 1 415 7.4E-63 T 22-04-2016 L21SP4_RS00815 508566e7566e50af3fd973002d17759b 418 Pfam PF00999 Sodium/hydrogen exchanger family 25 397 9.4E-30 T 22-04-2016 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 L21SP4_RS00815 508566e7566e50af3fd973002d17759b 418 PANTHER PTHR32507 1 415 7.4E-63 T 22-04-2016 L21SP4_RS05655 0e3a0832987088530c739d99563faa08 181 SUPERFAMILY SSF55277 2 50 5.23E-6 T 22-04-2016 IPR003169 GYF domain GO:0005515 L21SP4_RS05655 0e3a0832987088530c739d99563faa08 181 Gene3D G3DSA:3.30.1490.40 4 50 2.7E-6 T 22-04-2016 IPR003169 GYF domain GO:0005515 L21SP4_RS05655 0e3a0832987088530c739d99563faa08 181 Pfam PF14237 Domain of unknown function (DUF4339) 5 49 3.1E-15 T 22-04-2016 IPR025640 Domain of unknown function DUF4339 L21SP4_RS07270 11a73bfc4a1fb8f54ad48f2e0e754f46 539 PANTHER PTHR30383 329 539 4.2E-23 T 22-04-2016 L21SP4_RS07270 11a73bfc4a1fb8f54ad48f2e0e754f46 539 SUPERFAMILY SSF52266 346 537 1.65E-25 T 22-04-2016 IPR013830 SGNH hydrolase-type esterase domain L21SP4_RS07270 11a73bfc4a1fb8f54ad48f2e0e754f46 539 PANTHER PTHR30383:SF5 329 539 4.2E-23 T 22-04-2016 L21SP4_RS07270 11a73bfc4a1fb8f54ad48f2e0e754f46 539 Gene3D G3DSA:3.40.50.1110 346 537 2.5E-26 T 22-04-2016 IPR013830 SGNH hydrolase-type esterase domain L21SP4_RS07270 11a73bfc4a1fb8f54ad48f2e0e754f46 539 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 351 523 3.0E-14 T 22-04-2016 IPR013830 SGNH hydrolase-type esterase domain L21SP4_RS11130 8d3f075918e16998b89c0906a76f0eed 536 Pfam PF11028 Protein of unknown function (DUF2723) 78 163 2.0E-5 T 22-04-2016 IPR021280 Protein of unknown function DUF2723 L21SP4_RS00985 78b1c7f9b16ab8687cd90198cb082a33 475 Pfam PF04932 O-Antigen ligase 249 363 1.1E-6 T 22-04-2016 IPR007016 O-antigen ligase-related L21SP4_RS10990 5e2452b32e83d1d9a5d70054e38f4935 605 PANTHER PTHR41339 4 478 3.2E-25 T 22-04-2016 L21SP4_RS07450 f94a9e009118c5dc9a6334fa80f5e633 137 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 9 121 2.1E-22 T 22-04-2016 IPR000944 Transcription regulator Rrf2-type L21SP4_RS07450 f94a9e009118c5dc9a6334fa80f5e633 137 SUPERFAMILY SSF46785 3 123 1.26E-23 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS07450 f94a9e009118c5dc9a6334fa80f5e633 137 Gene3D G3DSA:1.10.10.10 10 124 2.9E-24 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS07450 f94a9e009118c5dc9a6334fa80f5e633 137 Pfam PF02082 Transcriptional regulator 10 73 1.1E-17 T 22-04-2016 IPR000944 Transcription regulator Rrf2-type L21SP4_RS07450 f94a9e009118c5dc9a6334fa80f5e633 137 PANTHER PTHR33221 15 124 4.2E-22 T 22-04-2016 L21SP4_RS07450 f94a9e009118c5dc9a6334fa80f5e633 137 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 40 58 - T 22-04-2016 IPR030489 Transcription regulator Rrf2-type, conserved site L21SP4_RS08735 5130391097450b16ab6dae85f26f8245 136 Pfam PF01850 PIN domain 3 117 1.1E-11 T 22-04-2016 IPR002716 PIN domain L21SP4_RS08735 5130391097450b16ab6dae85f26f8245 136 Gene3D G3DSA:3.40.50.1010 1 123 4.8E-23 T 22-04-2016 IPR029060 PIN domain-like L21SP4_RS08735 5130391097450b16ab6dae85f26f8245 136 SUPERFAMILY SSF88723 2 117 4.49E-17 T 22-04-2016 IPR029060 PIN domain-like L21SP4_RS08735 5130391097450b16ab6dae85f26f8245 136 PANTHER PTHR35901 1 136 2.1E-14 T 22-04-2016 L21SP4_RS10575 62a487ffb0968291beb4af4726dd47e3 393 Gene3D G3DSA:2.40.160.10 21 281 2.0E-9 T 22-04-2016 IPR023614 Porin domain L21SP4_RS10575 62a487ffb0968291beb4af4726dd47e3 393 SUPERFAMILY SSF56935 18 337 1.05E-9 T 22-04-2016 L21SP4_RS05015 b54305fea4bcd07e655964a1e901569e 194 Pfam PF13533 Biotin-lipoyl like 50 91 3.5E-6 T 22-04-2016 L21SP4_RS05015 b54305fea4bcd07e655964a1e901569e 194 Gene3D G3DSA:2.40.50.100 45 92 3.6E-6 T 22-04-2016 L21SP4_RS07010 42444395b1f7b04e983094939a217978 219 Gene3D G3DSA:3.30.559.10 1 213 9.7E-76 T 22-04-2016 IPR023213 Chloramphenicol acetyltransferase-like domain L21SP4_RS07010 42444395b1f7b04e983094939a217978 219 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 1 214 6.3E-75 T 22-04-2016 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 L21SP4_RS07010 42444395b1f7b04e983094939a217978 219 PANTHER PTHR23151 1 210 7.2E-86 T 22-04-2016 L21SP4_RS07010 42444395b1f7b04e983094939a217978 219 SUPERFAMILY SSF52777 1 213 6.23E-73 T 22-04-2016 L21SP4_RS08785 87def9650484193e4b3480dc9f10267f 660 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 65 236 7.1E-9 T 22-04-2016 L21SP4_RS03255 176551d035ed10a8febd092fb089cd6c 207 Pfam PF01863 Protein of unknown function DUF45 1 197 1.0E-57 T 22-04-2016 IPR002725 Protein of unknown function DUF45 L21SP4_RS03255 176551d035ed10a8febd092fb089cd6c 207 PANTHER PTHR30399 1 195 6.5E-31 T 22-04-2016 L21SP4_RS04515 1e1a8290bcfe0e0079726c961bfbb1f4 59 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 8 54 0.009 T 22-04-2016 IPR000238 Ribosome-binding factor A GO:0006364 L21SP4_RS04515 1e1a8290bcfe0e0079726c961bfbb1f4 59 SUPERFAMILY SSF89919 1 54 5.49E-9 T 22-04-2016 IPR023799 Ribosome-binding factor A domain L21SP4_RS04515 1e1a8290bcfe0e0079726c961bfbb1f4 59 Pfam PF02033 Ribosome-binding factor A 5 53 2.7E-6 T 22-04-2016 IPR000238 Ribosome-binding factor A GO:0006364 L21SP4_RS04515 1e1a8290bcfe0e0079726c961bfbb1f4 59 Gene3D G3DSA:3.30.300.20 1 54 2.2E-7 T 22-04-2016 IPR015946 K homology domain-like, alpha/beta L21SP4_RS07545 f7d823d19078c8b1c0dfc03d2ea09027 135 Pfam PF11149 Protein of unknown function (DUF2924) 7 48 1.2E-7 T 22-04-2016 IPR021322 Protein of unknown function DUF2924 L21SP4_RS07545 f7d823d19078c8b1c0dfc03d2ea09027 135 Gene3D G3DSA:2.115.10.20 52 130 8.1E-6 T 22-04-2016 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP4_RS07545 f7d823d19078c8b1c0dfc03d2ea09027 135 SUPERFAMILY SSF75005 48 132 2.97E-9 T 22-04-2016 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP4_RS10115 43339c61aba40a650187711c56d2ecf8 89 Pfam PF09012 FeoC like transcriptional regulator 2 72 6.9E-15 T 22-04-2016 IPR015102 Transcriptional regulator HTH-type, FeoC L21SP4_RS10115 43339c61aba40a650187711c56d2ecf8 89 Gene3D G3DSA:1.10.10.10 7 47 4.5E-7 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS10115 43339c61aba40a650187711c56d2ecf8 89 SUPERFAMILY SSF46785 2 63 3.54E-14 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS03740 78bcb95e7e494f249bde9a6aca5e1eaf 207 Gene3D G3DSA:3.40.50.150 10 206 8.6E-69 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS03740 78bcb95e7e494f249bde9a6aca5e1eaf 207 TIGRFAM TIGR00080 pimt: protein-L-isoaspartate O-methyltransferase 3 206 2.7E-64 T 22-04-2016 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 L21SP4_RS03740 78bcb95e7e494f249bde9a6aca5e1eaf 207 Hamap MF_00090 Protein-L-isoaspartate O-methyltransferase [pcm]. 1 207 35.844 T 22-04-2016 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 L21SP4_RS03740 78bcb95e7e494f249bde9a6aca5e1eaf 207 ProSitePatterns PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 130 145 - T 22-04-2016 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 L21SP4_RS03740 78bcb95e7e494f249bde9a6aca5e1eaf 207 PANTHER PTHR11579 4 207 3.5E-76 T 22-04-2016 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 L21SP4_RS03740 78bcb95e7e494f249bde9a6aca5e1eaf 207 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 8 206 6.4E-64 T 22-04-2016 L21SP4_RS03740 78bcb95e7e494f249bde9a6aca5e1eaf 207 SUPERFAMILY SSF53335 3 206 6.66E-52 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS06120 cd02780901b749ab8f6813156a900f48 112 Gene3D G3DSA:3.30.70.100 28 106 3.4E-6 T 22-04-2016 L21SP4_RS06120 cd02780901b749ab8f6813156a900f48 112 SUPERFAMILY SSF55008 26 100 1.96E-6 T 22-04-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 L21SP4_RS00255 2a47fbae33c9a9649da095c83376c252 98 PANTHER PTHR33930 1 94 5.6E-26 T 22-04-2016 L21SP4_RS00255 2a47fbae33c9a9649da095c83376c252 98 PANTHER PTHR33930:SF2 1 94 5.6E-26 T 22-04-2016 L21SP4_RS00255 2a47fbae33c9a9649da095c83376c252 98 Pfam PF02627 Carboxymuconolactone decarboxylase family 10 88 2.5E-20 T 22-04-2016 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 L21SP4_RS00255 2a47fbae33c9a9649da095c83376c252 98 SUPERFAMILY SSF69118 1 96 1.83E-26 T 22-04-2016 IPR029032 AhpD-like L21SP4_RS00255 2a47fbae33c9a9649da095c83376c252 98 Gene3D G3DSA:1.20.1290.10 1 95 4.0E-34 T 22-04-2016 IPR029032 AhpD-like L21SP4_RS00255 2a47fbae33c9a9649da095c83376c252 98 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 26 74 1.5E-13 T 22-04-2016 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 L21SP4_RS00600 418cc3dc81456967e5b1dd84c1d37693 119 SUPERFAMILY SSF53146 27 93 3.14E-9 T 22-04-2016 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis L21SP4_RS00600 418cc3dc81456967e5b1dd84c1d37693 119 Gene3D G3DSA:3.30.420.130 32 90 4.3E-5 T 22-04-2016 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis L21SP4_RS06295 0614e01cf1717bdfb5292a6f96cfeaf0 232 Gene3D G3DSA:3.40.50.1000 78 219 1.7E-8 T 22-04-2016 IPR023214 HAD-like domain L21SP4_RS06295 0614e01cf1717bdfb5292a6f96cfeaf0 232 SUPERFAMILY SSF56784 12 217 7.15E-14 T 22-04-2016 IPR023214 HAD-like domain L21SP4_RS07610 25fd387a31c566e31f20b670a58b03fd 212 Pfam PF01618 MotA/TolQ/ExbB proton channel family 96 187 2.4E-21 T 22-04-2016 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 L21SP4_RS07610 25fd387a31c566e31f20b670a58b03fd 212 PANTHER PTHR30625:SF8 95 173 5.7E-18 T 22-04-2016 L21SP4_RS07610 25fd387a31c566e31f20b670a58b03fd 212 PANTHER PTHR30625 95 173 5.7E-18 T 22-04-2016 L21SP4_RS06355 45765d83cb63ba32bb26f50bdc32a847 93 TIGRFAM TIGR02385 RelE_StbE: addiction module toxin, RelE/StbE family 15 88 2.4E-8 T 22-04-2016 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family L21SP4_RS06355 45765d83cb63ba32bb26f50bdc32a847 93 SUPERFAMILY SSF143011 6 83 8.5E-12 T 22-04-2016 L21SP4_RS09605 3cda4909c6c2bdf3131ea762fb332844 93 Gene3D G3DSA:3.40.1620.10 4 39 1.4E-4 T 22-04-2016 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM L21SP4_RS09605 3cda4909c6c2bdf3131ea762fb332844 93 SUPERFAMILY SSF143120 4 50 7.32E-5 T 22-04-2016 L21SP4_RS03360 758d5cd777e55f500852e0f416ec42cb 256 Gene3D G3DSA:3.40.50.150 79 192 3.5E-9 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS03360 758d5cd777e55f500852e0f416ec42cb 256 SUPERFAMILY SSF53335 43 190 4.04E-13 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP4_RS04835 3e528b1596658e9f5f71f3b80123dc1b 356 TIGRFAM TIGR04337 AmmeMemoSam_rS: AmmeMemoRadiSam system radical SAM enzyme 9 354 1.3E-171 T 22-04-2016 IPR027596 AmmeMemoRadiSam system radical SAM enzyme L21SP4_RS04835 3e528b1596658e9f5f71f3b80123dc1b 356 Pfam PF04055 Radical SAM superfamily 82 233 1.1E-17 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 L21SP4_RS04835 3e528b1596658e9f5f71f3b80123dc1b 356 SUPERFAMILY SSF102114 50 318 8.11E-38 T 22-04-2016 L21SP4_RS04835 3e528b1596658e9f5f71f3b80123dc1b 356 PANTHER PTHR30352 2 342 2.1E-145 T 22-04-2016 L21SP4_RS04835 3e528b1596658e9f5f71f3b80123dc1b 356 Gene3D G3DSA:3.80.30.10 123 288 3.2E-35 T 22-04-2016 L21SP4_RS04835 3e528b1596658e9f5f71f3b80123dc1b 356 PANTHER PTHR30352:SF5 2 342 2.1E-145 T 22-04-2016 L21SP4_RS04835 3e528b1596658e9f5f71f3b80123dc1b 356 PIRSF PIRSF004869 5 315 5.8E-93 T 22-04-2016 IPR016431 Pyruvate-formate lyase-activating enzyme, predicted L21SP4_RS04485 42e7feb384c5f7715c1e30f176134a4e 441 SUPERFAMILY SSF53098 313 412 7.28E-8 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP4_RS04485 42e7feb384c5f7715c1e30f176134a4e 441 Pfam PF13701 Transposase DDE domain group 1 49 438 3.4E-30 T 22-04-2016 IPR025668 Transposase DDE domain L21SP4_RS00385 a83f959f9904f593ff8b0e29ee0de50f 504 SUPERFAMILY SSF48239 152 414 1.02E-28 T 22-04-2016 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid L21SP4_RS00385 a83f959f9904f593ff8b0e29ee0de50f 504 SUPERFAMILY SSF48239 461 480 1.02E-28 T 22-04-2016 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid L21SP4_RS00385 a83f959f9904f593ff8b0e29ee0de50f 504 Gene3D G3DSA:1.50.10.20 354 477 1.1E-20 T 22-04-2016 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid L21SP4_RS00385 a83f959f9904f593ff8b0e29ee0de50f 504 Gene3D G3DSA:1.50.10.20 152 293 1.1E-20 T 22-04-2016 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid L21SP4_RS01010 af6eeb5568f0f98782cf307d667036ee 294 Pfam PF08340 Domain of unknown function (DUF1732) 210 294 2.2E-32 T 22-04-2016 IPR013551 Domain of unknown function DUF1732 L21SP4_RS01010 af6eeb5568f0f98782cf307d667036ee 294 PANTHER PTHR30636 2 294 3.9E-77 T 22-04-2016 L21SP4_RS01010 af6eeb5568f0f98782cf307d667036ee 294 Pfam PF03755 YicC-like family, N-terminal region 3 157 3.9E-35 T 22-04-2016 IPR013527 YicC-like, N-terminal L21SP4_RS01010 af6eeb5568f0f98782cf307d667036ee 294 TIGRFAM TIGR00255 TIGR00255: TIGR00255 family protein 3 294 2.2E-59 T 22-04-2016 IPR005229 Conserved hypothetical protein CHP00255 L21SP4_RS10310 0add59804660c1f66deb10f6c3d61d05 412 Gene3D G3DSA:2.40.160.60 21 412 8.7E-92 T 22-04-2016 L21SP4_RS10310 0add59804660c1f66deb10f6c3d61d05 412 SUPERFAMILY SSF56935 21 412 1.92E-63 T 22-04-2016 L21SP4_RS10310 0add59804660c1f66deb10f6c3d61d05 412 PANTHER PTHR35093 1 412 4.5E-62 T 22-04-2016 L21SP4_RS10310 0add59804660c1f66deb10f6c3d61d05 412 Pfam PF03349 Outer membrane protein transport protein (OMPP1/FadL/TodX) 14 412 4.5E-64 T 22-04-2016 IPR005017 Outer membrane protein transport protein (OMPP1/FadL/TodX) L21SP4_RS10310 0add59804660c1f66deb10f6c3d61d05 412 PANTHER PTHR35093:SF2 1 412 4.5E-62 T 22-04-2016 L21SP4_RS00760 4cf74e228763b2b28aff3a65a0bf392f 259 TIGRFAM TIGR00056 TIGR00056: ABC transport permease subunit 7 259 2.5E-80 T 22-04-2016 IPR003453 ABC transport permease subunit MlaE, Proteobacteria L21SP4_RS00760 4cf74e228763b2b28aff3a65a0bf392f 259 Pfam PF02405 Permease MlaE 47 256 1.3E-80 T 22-04-2016 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 L21SP4_RS00760 4cf74e228763b2b28aff3a65a0bf392f 259 PANTHER PTHR30188:SF4 5 259 9.9E-113 T 22-04-2016 L21SP4_RS00760 4cf74e228763b2b28aff3a65a0bf392f 259 PANTHER PTHR30188 5 259 9.9E-113 T 22-04-2016 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 L21SP4_RS05590 36ba8db32088c540766d22368245f015 172 Pfam PF07681 DoxX 16 127 8.3E-5 T 22-04-2016 IPR032808 DoxX family L21SP4_RS09055 bd105dea2186869f03a9a8d1edda96d1 462 Pfam PF11013 Protein of unknown function (DUF2851) 16 392 4.0E-51 T 22-04-2016 IPR021272 Protein of unknown function DUF2851 L21SP4_RS09830 e733890ec7826abf957005e64f295b59 908 TIGRFAM TIGR01865 cas_Csn1: CRISPR subtype II RNA-guided endonuclease Cas9 6 626 2.7E-71 T 22-04-2016 IPR028629 CRISPR-associated endonuclease Cas9 GO:0004519 L21SP4_RS09830 e733890ec7826abf957005e64f295b59 908 Pfam PF13395 HNH endonuclease 435 491 1.2E-17 T 22-04-2016 IPR003615 HNH nuclease L21SP4_RS02215 5121fb590530e4487bb1bfbcf0b04159 183 SUPERFAMILY SSF50199 41 157 1.44E-12 T 22-04-2016 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold L21SP4_RS02215 5121fb590530e4487bb1bfbcf0b04159 183 Gene3D G3DSA:2.40.50.90 41 149 1.1E-10 T 22-04-2016 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold L21SP4_RS09745 063dbd0a563e972ba022503cc2dab826 80 Pfam PF06305 Protein of unknown function (DUF1049) 21 68 4.1E-11 T 22-04-2016 IPR010445 Lipopolysaccharide assembly protein A domain GO:0005887 L21SP4_RS02270 e8948b16f827066134e8bc60d10778fb 287 Pfam PF08843 Nucleotidyl transferase AbiEii toxin, Type IV TA system 34 256 9.0E-27 T 22-04-2016 IPR014942 Nucleotidyl transferase AbiEii toxin, Type IV TA system L21SP4_RS04080 a9c371eb6f03b57c81cb450733d76c22 269 Pfam PF01618 MotA/TolQ/ExbB proton channel family 113 235 4.0E-31 T 22-04-2016 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 L21SP4_RS04080 a9c371eb6f03b57c81cb450733d76c22 269 PANTHER PTHR30625:SF0 39 268 5.9E-46 T 22-04-2016 L21SP4_RS04080 a9c371eb6f03b57c81cb450733d76c22 269 PANTHER PTHR30625 39 268 5.9E-46 T 22-04-2016 L21SP4_RS11380 3ec882abc193c95ffae6a68b400ccbd0 116 TIGRFAM TIGR04535 ferrit_encaps: ferritin-like protein 7 115 8.9E-45 T 22-04-2016 IPR030907 Ferritin-like protein L21SP4_RS11380 3ec882abc193c95ffae6a68b400ccbd0 116 Gene3D G3DSA:1.20.1260.10 12 70 1.6E-11 T 22-04-2016 IPR012347 Ferritin-related L21SP4_RS11380 3ec882abc193c95ffae6a68b400ccbd0 116 SUPERFAMILY SSF47240 15 89 6.41E-20 T 22-04-2016 IPR009078 Ferritin-like superfamily L21SP4_RS05130 0aa51a16ba482cac75fdd0c686a34e0a 430 SUPERFAMILY SSF53756 60 427 1.78E-18 T 22-04-2016 L21SP4_RS05130 0aa51a16ba482cac75fdd0c686a34e0a 430 Pfam PF00534 Glycosyl transferases group 1 318 409 1.4E-7 T 22-04-2016 IPR001296 Glycosyl transferase, family 1 L21SP4_RS05130 0aa51a16ba482cac75fdd0c686a34e0a 430 Pfam PF04413 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) 35 216 1.3E-54 T 22-04-2016 IPR007507 3-deoxy-D-manno-octulosonic-acid transferase, N-terminal KEGG: 00540+2.4.99.12|MetaCyc: PWY-7675|UniPathway: UPA00958 L21SP4_RS05130 0aa51a16ba482cac75fdd0c686a34e0a 430 PANTHER PTHR23417 196 426 9.5E-79 T 22-04-2016 L21SP4_RS05130 0aa51a16ba482cac75fdd0c686a34e0a 430 PANTHER PTHR23417 136 146 9.5E-79 T 22-04-2016 L21SP4_RS05130 0aa51a16ba482cac75fdd0c686a34e0a 430 PANTHER PTHR23417 1 118 9.5E-79 T 22-04-2016 L21SP4_RS05130 0aa51a16ba482cac75fdd0c686a34e0a 430 PANTHER PTHR23417:SF2 196 426 9.5E-79 T 22-04-2016 L21SP4_RS05130 0aa51a16ba482cac75fdd0c686a34e0a 430 PANTHER PTHR23417:SF2 136 146 9.5E-79 T 22-04-2016 L21SP4_RS05130 0aa51a16ba482cac75fdd0c686a34e0a 430 PANTHER PTHR23417:SF2 1 118 9.5E-79 T 22-04-2016 L21SP4_RS00575 58cf188f1084e3a4ea02e61d78268cf2 127 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 16 89 1.1E-9 T 22-04-2016 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 L21SP4_RS00575 58cf188f1084e3a4ea02e61d78268cf2 127 Gene3D G3DSA:2.30.110.10 4 118 1.9E-15 T 22-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 L21SP4_RS00575 58cf188f1084e3a4ea02e61d78268cf2 127 SUPERFAMILY SSF50475 13 117 8.68E-16 T 22-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 L21SP4_RS11810 c7010b442ecc919096c5aabc26efef25 257 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 232 255 3.0E-4 T 22-04-2016 IPR013424 PEP-CTERM protein-sorting domain L21SP4_RS11980 8d8d9e70c12d7f6ad3ce61f252156468 242 Pfam PF11984 Protein of unknown function (DUF3485) 14 184 1.3E-16 T 22-04-2016 IPR014263 Methanolan biosynthesis EpsI L21SP4_RS07830 b7ceea6ac52286bc72eaed21e82430bb 278 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 10 32 2.6E-5 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site L21SP4_RS07830 b7ceea6ac52286bc72eaed21e82430bb 278 SUPERFAMILY SSF54523 12 78 3.45E-9 T 22-04-2016 L21SP4_RS07830 b7ceea6ac52286bc72eaed21e82430bb 278 Pfam PF13544 Type IV pilin N-term methylation site GFxxxE 6 30 2.1E-7 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site L21SP4_RS07830 b7ceea6ac52286bc72eaed21e82430bb 278 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 10 30 - T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site L21SP4_RS11715 ccd64f5c75f5ef6fcf4f9a170ea0c2b9 147 Gene3D G3DSA:3.40.50.1820 7 119 3.2E-6 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold L21SP4_RS12080 e5cd0325d1403cfbe9cf54f3d01c4036 198 PANTHER PTHR23407:SF1 1 197 3.3E-44 T 22-04-2016 IPR002698 5-formyltetrahydrofolate cyclo-ligase L21SP4_RS12080 e5cd0325d1403cfbe9cf54f3d01c4036 198 SUPERFAMILY SSF100950 6 184 1.67E-44 T 22-04-2016 L21SP4_RS12080 e5cd0325d1403cfbe9cf54f3d01c4036 198 PIRSF PIRSF006806 3 181 1.2E-36 T 22-04-2016 IPR002698 5-formyltetrahydrofolate cyclo-ligase L21SP4_RS12080 e5cd0325d1403cfbe9cf54f3d01c4036 198 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 6 178 8.8E-42 T 22-04-2016 IPR002698 5-formyltetrahydrofolate cyclo-ligase L21SP4_RS12080 e5cd0325d1403cfbe9cf54f3d01c4036 198 PANTHER PTHR23407 1 197 3.3E-44 T 22-04-2016 L21SP4_RS12080 e5cd0325d1403cfbe9cf54f3d01c4036 198 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 6 178 6.3E-37 T 22-04-2016 IPR002698 5-formyltetrahydrofolate cyclo-ligase L21SP4_RS12080 e5cd0325d1403cfbe9cf54f3d01c4036 198 Gene3D G3DSA:3.40.50.10420 5 183 4.4E-48 T 22-04-2016 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain L21SP4_RS07515 66f71b3ad90b01ffeda020d942a821b4 233 Pfam PF06114 Domain of unknown function (DUF955) 88 215 1.6E-12 T 22-04-2016 IPR010359 HTH domain, IrrE-type L21SP4_RS02390 4e66810417edd4b10c7a95a798ca53b4 605 SUPERFAMILY SSF50939 45 346 2.09E-12 T 22-04-2016 IPR011040 Sialidases L21SP4_RS02390 4e66810417edd4b10c7a95a798ca53b4 605 Gene3D G3DSA:2.120.10.10 40 174 4.8E-13 T 22-04-2016 IPR011040 Sialidases L21SP4_RS06490 116ce34c382e365aad10024bb0a799ad 136 Pfam PF13366 PD-(D/E)XK nuclease superfamily 8 123 7.3E-41 T 22-04-2016 IPR026350 GxxExxY protein L21SP4_RS06490 116ce34c382e365aad10024bb0a799ad 136 TIGRFAM TIGR04256 GxxExxY: GxxExxY protein 9 125 5.4E-42 T 22-04-2016 IPR026350 GxxExxY protein L21SP4_RS09385 18058f4a6ada76312e1eeb85481c68b6 338 Gene3D G3DSA:3.20.20.210 2 329 4.4E-48 T 22-04-2016 L21SP4_RS09385 18058f4a6ada76312e1eeb85481c68b6 338 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 3 326 6.3E-47 T 22-04-2016 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 L21SP4_RS09385 18058f4a6ada76312e1eeb85481c68b6 338 SUPERFAMILY SSF51726 3 327 2.44E-39 T 22-04-2016 L21SP4_RS02225 e39b42f8990f9b67a54aba98a6642e36 109 Gene3D G3DSA:3.30.420.130 1 98 3.2E-29 T 22-04-2016 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis L21SP4_RS02225 e39b42f8990f9b67a54aba98a6642e36 109 PANTHER PTHR33937:SF3 1 109 2.6E-24 T 22-04-2016 L21SP4_RS02225 e39b42f8990f9b67a54aba98a6642e36 109 SUPERFAMILY SSF53146 1 109 2.49E-28 T 22-04-2016 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis L21SP4_RS02225 e39b42f8990f9b67a54aba98a6642e36 109 PANTHER PTHR33937 1 109 2.6E-24 T 22-04-2016 L21SP4_RS02225 e39b42f8990f9b67a54aba98a6642e36 109 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 9 96 4.0E-20 T 22-04-2016 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis L21SP4_RS04675 d2d261411bbdd325244e9218a303b60a 113 Pfam PF00403 Heavy-metal-associated domain 41 101 9.9E-11 T 22-04-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 L21SP4_RS04675 d2d261411bbdd325244e9218a303b60a 113 SUPERFAMILY SSF55008 34 105 2.36E-14 T 22-04-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 L21SP4_RS04675 d2d261411bbdd325244e9218a303b60a 113 Gene3D G3DSA:3.30.70.100 35 104 7.2E-15 T 22-04-2016 L21SP4_RS01555 f73a9c236fc5dd34c79451b8183ba07a 364 SUPERFAMILY SSF51726 101 268 1.2E-6 T 22-04-2016 L21SP4_RS01555 f73a9c236fc5dd34c79451b8183ba07a 364 Gene3D G3DSA:3.20.20.210 101 262 9.3E-11 T 22-04-2016 L21SP4_RS00785 4a70ba3e785836e4ec2ade56751e9818 236 Pfam PF13544 Type IV pilin N-term methylation site GFxxxE 9 31 3.5E-6 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site L21SP4_RS00785 4a70ba3e785836e4ec2ade56751e9818 236 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 10 30 - T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site L21SP4_RS00675 9ef1b20ab3077bd7b8070bfc282efc49 354 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 153 350 8.3E-13 T 22-04-2016 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 L21SP4_RS00675 9ef1b20ab3077bd7b8070bfc282efc49 354 SUPERFAMILY SSF51726 2 354 1.53E-30 T 22-04-2016 L21SP4_RS00675 9ef1b20ab3077bd7b8070bfc282efc49 354 Gene3D G3DSA:3.20.20.210 78 352 4.7E-28 T 22-04-2016 L21SP4_RS00380 ff913c3989d0a42c2510afb1f0ee78d9 94 SUPERFAMILY SSF51126 20 77 4.04E-11 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor L21SP4_RS00380 ff913c3989d0a42c2510afb1f0ee78d9 94 Gene3D G3DSA:2.160.20.10 31 77 2.9E-10 T 22-04-2016 IPR012334 Pectin lyase fold L21SP4_RS09410 c59b1ae394c52d6061a1dded67e45a0a 636 SUPERFAMILY SSF89550 312 543 9.42E-15 T 22-04-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 L21SP4_RS05860 5ce95a6d4b2980492ff3018e894539f4 304 Pfam PF13469 Sulfotransferase family 7 198 2.7E-12 T 22-04-2016 L21SP4_RS05860 5ce95a6d4b2980492ff3018e894539f4 304 SUPERFAMILY SSF52540 74 219 2.37E-22 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS05860 5ce95a6d4b2980492ff3018e894539f4 304 SUPERFAMILY SSF52540 3 34 2.37E-22 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS05860 5ce95a6d4b2980492ff3018e894539f4 304 Gene3D G3DSA:3.40.50.300 75 299 6.2E-20 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS05860 5ce95a6d4b2980492ff3018e894539f4 304 Gene3D G3DSA:3.40.50.300 4 42 6.2E-20 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS06770 d01216462e135162df12a75f6c3b9953 62 Pfam PF03683 Uncharacterised protein family (UPF0175) 3 57 7.5E-13 T 22-04-2016 IPR005368 Uncharacterised protein family UPF0175 L21SP4_RS00040 a3a384faa50ea197f251837d0c85c63e 270 Pfam PF05170 AsmA family 5 162 1.4E-7 T 22-04-2016 IPR007844 AsmA L21SP4_RS03580 302114ab542c3b6887f1921eaca06e63 276 Pfam PF00263 Bacterial type II and III secretion system protein 137 241 1.5E-9 T 22-04-2016 IPR004846 Type II/III secretion system GO:0009306 L21SP4_RS12155 d748d76f7b6519195748206f31e28c8b 244 Pfam PF12730 ABC-2 family transporter protein 23 172 1.1E-6 T 22-04-2016 IPR032688 ABC-2 family transporter protein GO:0006810 L21SP4_RS12155 d748d76f7b6519195748206f31e28c8b 244 PANTHER PTHR30294 1 234 1.2E-74 T 22-04-2016 L21SP4_RS12155 d748d76f7b6519195748206f31e28c8b 244 PANTHER PTHR30294:SF5 1 234 1.2E-74 T 22-04-2016 L21SP4_RS00950 f9a3d6ed97109da7cb1690f6080765ff 304 SUPERFAMILY SSF53448 3 250 5.33E-46 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases L21SP4_RS00950 f9a3d6ed97109da7cb1690f6080765ff 304 PANTHER PTHR22916 3 293 2.5E-35 T 22-04-2016 L21SP4_RS00950 f9a3d6ed97109da7cb1690f6080765ff 304 Pfam PF13641 Glycosyltransferase like family 2 3 208 2.0E-21 T 22-04-2016 L21SP4_RS00950 f9a3d6ed97109da7cb1690f6080765ff 304 Gene3D G3DSA:3.90.550.10 3 253 3.1E-39 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases L21SP4_RS12010 c5fb0b56f9a8bc9a41ce3dbb61e0dd71 743 SUPERFAMILY SSF48208 352 549 5.16E-24 T 22-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP4_RS12010 c5fb0b56f9a8bc9a41ce3dbb61e0dd71 743 SUPERFAMILY SSF48208 588 710 5.16E-24 T 22-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP4_RS12010 c5fb0b56f9a8bc9a41ce3dbb61e0dd71 743 Gene3D G3DSA:2.60.420.10 661 707 4.8E-6 T 22-04-2016 L21SP4_RS04300 993843e7738f290f578e79e4b2dd0bb6 110 Gene3D G3DSA:2.30.30.110 2 105 2.0E-9 T 22-04-2016 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor L21SP4_RS04300 993843e7738f290f578e79e4b2dd0bb6 110 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 3 104 9.1E-8 T 22-04-2016 IPR003477 mRNA interferase PemK-like protein GO:0003677 L21SP4_RS04300 993843e7738f290f578e79e4b2dd0bb6 110 SUPERFAMILY SSF50118 2 107 5.01E-11 T 22-04-2016 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor L21SP4_RS11440 4fa12ef8d03a05681d5279cb4e085fe8 76 Gene3D G3DSA:2.20.28.10 40 72 6.1E-5 T 22-04-2016 IPR004039 Rubredoxin-type fold L21SP4_RS08585 0b576f1faedb8d5b40d52c283497d60e 485 Pfam PF06253 Trimethylamine methyltransferase (MTTB) 15 476 1.8E-101 T 22-04-2016 IPR010426 Trimethylamine methyltransferase GO:0008168|GO:0015948 KEGG: 00680+2.1.1.250|MetaCyc: PWY-5250|UniPathway: UPA00645 L21SP4_RS11880 0c97b04ea2a85376ae78bd4006c5ca87 672 SUPERFAMILY SSF48208 290 542 9.86E-10 T 22-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP4_RS08115 001e337019250985a611889536a81e9e 157 SUPERFAMILY SSF58113 39 155 3.27E-6 T 22-04-2016 L21SP4_RS08115 001e337019250985a611889536a81e9e 157 Gene3D G3DSA:1.20.120.20 41 154 1.6E-6 T 22-04-2016 L21SP4_RS05835 da8d1380111d39489114dfd5d52d159a 289 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 1 276 1.1E-40 T 22-04-2016 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 L21SP4_RS05835 da8d1380111d39489114dfd5d52d159a 289 PANTHER PTHR30606 1 276 5.0E-53 T 22-04-2016 L21SP4_RS05220 5c2ba9612d2db3196167ef977c12ce76 567 TIGRFAM TIGR03790 TIGR03790: TIGR03790 family protein 30 349 4.3E-27 T 22-04-2016 IPR022265 Conserved hypothetical protein CHP03790 L21SP4_RS07360 04b97f0d1a79ecd3765e5647971f5d6c 159 PANTHER PTHR31285 3 150 1.9E-26 T 22-04-2016 L21SP4_RS07360 04b97f0d1a79ecd3765e5647971f5d6c 159 PANTHER PTHR31285:SF0 3 150 1.9E-26 T 22-04-2016 L21SP4_RS06540 88e1965145f01e1fa1ecb9b413ac4f7d 566 Gene3D G3DSA:2.160.20.10 420 505 9.3E-20 T 22-04-2016 IPR012334 Pectin lyase fold L21SP4_RS06540 88e1965145f01e1fa1ecb9b413ac4f7d 566 Gene3D G3DSA:2.160.20.10 57 170 9.3E-20 T 22-04-2016 IPR012334 Pectin lyase fold L21SP4_RS06540 88e1965145f01e1fa1ecb9b413ac4f7d 566 Gene3D G3DSA:2.160.20.10 258 349 9.3E-20 T 22-04-2016 IPR012334 Pectin lyase fold L21SP4_RS06540 88e1965145f01e1fa1ecb9b413ac4f7d 566 SUPERFAMILY SSF51126 56 182 1.31E-27 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor L21SP4_RS06540 88e1965145f01e1fa1ecb9b413ac4f7d 566 SUPERFAMILY SSF51126 426 505 1.31E-27 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor L21SP4_RS06540 88e1965145f01e1fa1ecb9b413ac4f7d 566 SUPERFAMILY SSF51126 253 346 1.31E-27 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor L21SP4_RS06540 88e1965145f01e1fa1ecb9b413ac4f7d 566 ProSitePatterns PS00822 Cytochrome c and c1 heme lyases signature 2. 417 423 - T 22-04-2016 IPR000511 Cytochrome c/c1 haem-lyase GO:0004408|GO:0005739 KEGG: 00860+4.4.1.17 L21SP4_RS03180 3ff550a5c0416a614be2138851d7d9a0 430 Pfam PF09861 Domain of unknown function (DUF2088) 36 183 3.3E-9 T 22-04-2016 IPR018657 Domain of unknown function DUF2088 L21SP4_RS04545 c0a87353bcf6286f019fee6320b4d083 622 Gene3D G3DSA:2.160.20.10 12 201 1.6E-16 T 22-04-2016 IPR012334 Pectin lyase fold L21SP4_RS04545 c0a87353bcf6286f019fee6320b4d083 622 Gene3D G3DSA:2.160.20.10 457 564 1.6E-16 T 22-04-2016 IPR012334 Pectin lyase fold L21SP4_RS04545 c0a87353bcf6286f019fee6320b4d083 622 SUPERFAMILY SSF51126 189 202 5.83E-18 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor L21SP4_RS04545 c0a87353bcf6286f019fee6320b4d083 622 SUPERFAMILY SSF51126 437 561 5.83E-18 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor L21SP4_RS04545 c0a87353bcf6286f019fee6320b4d083 622 SUPERFAMILY SSF51126 6 126 5.83E-18 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor L21SP4_RS06175 e8cb1ddd36204bc68aa55d2edc522b73 578 Pfam PF09818 Predicted ATPase of the ABC class 6 432 2.0E-77 T 22-04-2016 IPR019195 ABC transporter, ATPase, putative L21SP4_RS06175 e8cb1ddd36204bc68aa55d2edc522b73 578 PANTHER PTHR38149 1 578 1.5E-47 T 22-04-2016 L21SP4_RS02870 a8044e167b1a9e6ef7259f60dd3cf5ec 481 Pfam PF04986 Putative transposase 175 357 2.8E-23 T 22-04-2016 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 L21SP4_RS02870 a8044e167b1a9e6ef7259f60dd3cf5ec 481 Pfam PF14319 Transposase zinc-binding domain 34 148 2.3E-19 T 22-04-2016 IPR026889 Transposase zinc-binding domain L21SP4_RS06055 73e5b489ae38d0585824bdf666870a1d 230 Pfam PF07385 Protein of unknown function (DUF1498) 1 223 7.7E-96 T 22-04-2016 IPR010864 Protein of unknown function DUF1498 KEGG: 00040+5.3.1.15 L21SP4_RS04960 9d1c829e8779e2b23c4f1edd7924088a 754 Pfam PF13584 Oxygen tolerance 39 421 6.4E-29 T 22-04-2016 IPR025738 Aerotolerance-related protein BatD L21SP4_RS09575 bd8973c8d04d86fc7cc5587780ba2e4e 276 SUPERFAMILY SSF55681 3 239 6.46E-58 T 22-04-2016 L21SP4_RS09575 bd8973c8d04d86fc7cc5587780ba2e4e 276 PANTHER PTHR12561:SF3 2 263 1.8E-71 T 22-04-2016 L21SP4_RS09575 bd8973c8d04d86fc7cc5587780ba2e4e 276 Gene3D G3DSA:3.90.1550.10 4 239 2.0E-62 T 22-04-2016 L21SP4_RS09575 bd8973c8d04d86fc7cc5587780ba2e4e 276 PANTHER PTHR12561 2 263 1.8E-71 T 22-04-2016 L21SP4_RS04720 7e1f3120dff021f4cbb06973972e1e1e 908 Gene3D G3DSA:3.40.50.300 29 84 1.8E-8 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS04720 7e1f3120dff021f4cbb06973972e1e1e 908 Gene3D G3DSA:3.40.50.300 784 889 1.8E-8 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS04720 7e1f3120dff021f4cbb06973972e1e1e 908 Gene3D G3DSA:3.40.50.300 347 348 1.8E-8 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS04720 7e1f3120dff021f4cbb06973972e1e1e 908 Gene3D G3DSA:3.40.50.300 131 132 1.8E-8 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS04720 7e1f3120dff021f4cbb06973972e1e1e 908 Gene3D G3DSA:3.40.50.300 194 251 1.8E-8 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS04720 7e1f3120dff021f4cbb06973972e1e1e 908 SUPERFAMILY SSF52540 30 126 8.38E-7 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS04720 7e1f3120dff021f4cbb06973972e1e1e 908 SUPERFAMILY SSF52540 777 890 8.38E-7 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP4_RS11450 800c00167dce94151f2614927e394112 150 PANTHER PTHR30558 5 150 4.0E-16 T 22-04-2016 L21SP4_RS11450 800c00167dce94151f2614927e394112 150 Pfam PF02472 Biopolymer transport protein ExbD/TolR 29 145 1.9E-15 T 22-04-2016 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 L21SP4_RS03940 b031347b9482a8293cf90f88433da831 284 Pfam PF04015 Domain of unknown function (DUF362) 52 247 5.3E-37 T 22-04-2016 IPR007160 Domain of unknown function DUF362 L21SP4_RS07975 d15718369e9c8c4a1c2f1531c7ef2a91 135 Pfam PF07291 Methylamine utilisation protein MauE 2 121 5.7E-14 T 22-04-2016 IPR009908 Methylamine utilisation protein, MauE GO:0016021|GO:0030416 UniPathway: UPA00895 L21SP4_RS03080 2d74512ec0bd6dfa64f28a1a9ac83295 578 Pfam PF04932 O-Antigen ligase 347 496 2.5E-8 T 22-04-2016 IPR007016 O-antigen ligase-related L21SP4_RS05960 24988c83300611058f2a11c667aed1ea 89 SUPERFAMILY SSF48295 5 42 3.14E-5 T 22-04-2016 IPR010921 Trp repressor/replication initiator GO:0043565 L21SP4_RS07220 f4b778dc953f96745fdd52f3abcb874d 74 SUPERFAMILY SSF46689 2 68 2.51E-22 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 L21SP4_RS07220 f4b778dc953f96745fdd52f3abcb874d 74 PANTHER PTHR34849:SF5 1 69 6.4E-36 T 22-04-2016 L21SP4_RS07220 f4b778dc953f96745fdd52f3abcb874d 74 Gene3D G3DSA:1.10.10.10 7 69 2.9E-28 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP4_RS07220 f4b778dc953f96745fdd52f3abcb874d 74 Pfam PF04255 Protein of unknown function (DUF433) 7 62 1.9E-25 T 22-04-2016 IPR007367 Protein of unknown function DUF433 L21SP4_RS07220 f4b778dc953f96745fdd52f3abcb874d 74 PANTHER PTHR34849 1 69 6.4E-36 T 22-04-2016 L21SP4_RS00625 940dd4a7b631d1318cbd05cb0924c769 85 Pfam PF04304 Protein of unknown function (DUF454) 14 74 1.6E-7 T 22-04-2016 IPR007401 Protein of unknown function DUF454 L21SP4_RS09185 b5b21507915d1b43e49e8fd6a2eec070 182 SUPERFAMILY SSF56925 66 182 1.36E-9 T 22-04-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 L21SP4_RS09185 b5b21507915d1b43e49e8fd6a2eec070 182 Gene3D G3DSA:2.40.160.20 78 180 7.1E-6 T 22-04-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 L21SP4_RS10100 f982b1fb20dd4fb7e2b48c87035eff5b 251 Gene3D G3DSA:2.50.20.10 117 241 4.2E-18 T 22-04-2016 L21SP4_RS10100 f982b1fb20dd4fb7e2b48c87035eff5b 251 Pfam PF17131 Outer membrane lipoprotein-sorting protein 125 240 5.2E-12 T 22-04-2016 IPR033399 Putative outer membrane lipoprotein-sorting protein L21SP4_RS00285 65c6c747b8941e555ee94cf21b5ea3bd 257 SUPERFAMILY SSF63825 9 224 7.06E-14 T 22-04-2016 L21SP4_RS00285 65c6c747b8941e555ee94cf21b5ea3bd 257 Gene3D G3DSA:2.120.10.30 6 206 1.1E-11 T 22-04-2016 IPR011042 Six-bladed beta-propeller, TolB-like L21SP4_RS11415 78da285288c75d623be07c30cfa9778a 571 Gene3D G3DSA:1.25.40.10 366 532 6.9E-4 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP4_RS07490 a7d6d665e59794fb52ab0c54662b4686 402 Pfam PF13289 SIR2-like domain 156 307 6.3E-24 T 22-04-2016 L21SP4_RS07970 4b7ea0e16d10a06f58edff950338f28b 154 Pfam PF05433 Glycine zipper 2TM domain 62 102 5.1E-6 T 22-04-2016 IPR008816 Glycine zipper 2TM domain GO:0019867 L21SP4_RS07970 4b7ea0e16d10a06f58edff950338f28b 154 PANTHER PTHR35603 2 148 1.2E-26 T 22-04-2016 L21SP4_RS01000 6a02efa9127d80dfcec217d41194f1a2 352 SUPERFAMILY SSF109604 128 240 2.27E-5 T 22-04-2016 L21SP4_RS01000 6a02efa9127d80dfcec217d41194f1a2 352 Pfam PF01966 HD domain 130 243 4.8E-5 T 22-04-2016 IPR006674 HD domain L21SP4_RS01675 5fb21320637d19cd618a8ceaba3a8cd4 103 Pfam PF04977 Septum formation initiator 17 91 9.1E-9 T 22-04-2016 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 L21SP4_RS01205 4cf84c4fdb230fcd2e9a1ae49dc3898c 581 Pfam PF14238 Domain of unknown function (DUF4340) 473 559 3.4E-8 T 22-04-2016 IPR025641 Domain of unknown function DUF4340 L21SP4_RS01205 4cf84c4fdb230fcd2e9a1ae49dc3898c 581 Pfam PF14238 Domain of unknown function (DUF4340) 60 240 2.6E-22 T 22-04-2016 IPR025641 Domain of unknown function DUF4340 L21SP4_RS01205 4cf84c4fdb230fcd2e9a1ae49dc3898c 581 Pfam PF14238 Domain of unknown function (DUF4340) 226 370 2.2E-13 T 22-04-2016 IPR025641 Domain of unknown function DUF4340 L21SP4_RS08970 2fb8c8a31b8784a14ac4305c18cc8d78 316 Pfam PF14100 Methane oxygenase PmoA 49 308 9.5E-59 T 22-04-2016 IPR029475 Methane oxygenase PmoA L21SP4_RS05885 a3b6c05c558e871843b9677ab7ce71f7 297 Gene3D G3DSA:3.40.50.2000 150 261 7.6E-11 T 22-04-2016 L21SP4_RS05885 a3b6c05c558e871843b9677ab7ce71f7 297 SUPERFAMILY SSF53756 36 269 1.08E-11 T 22-04-2016 L21SP4_RS09245 199047e11e55e459df81bd9c9dffe58e 245 Pfam PF04402 Protein of unknown function (DUF541) 16 196 1.5E-12 T 22-04-2016 IPR007497 Protein of unknown function DUF541 L21SP4_RS05415 4c237e7fb63e5bce8330fc580e71b5ef 216 Pfam PF01618 MotA/TolQ/ExbB proton channel family 73 185 3.9E-30 T 22-04-2016 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 L21SP4_RS05415 4c237e7fb63e5bce8330fc580e71b5ef 216 PANTHER PTHR30625 1 214 5.6E-41 T 22-04-2016 L21SP4_RS11265 58808d19cc334df9b9aad1081c17fee8 448 PANTHER PTHR36932 19 331 1.9E-13 T 22-04-2016 L21SP4_RS11265 58808d19cc334df9b9aad1081c17fee8 448 SUPERFAMILY SSF56801 45 278 6.87E-9 T 22-04-2016 L21SP4_RS06405 708dd960cbf35a23b3970e1a9f5e0eca 150 Gene3D G3DSA:1.20.1260.10 2 140 2.8E-12 T 22-04-2016 IPR012347 Ferritin-related L21SP4_RS06345 fa29cbad8492f848fe33a73a919689ae 213 Pfam PF13338 Transcriptional regulator, AbiEi antitoxin 34 106 6.3E-8 T 22-04-2016 IPR025159 Transcriptional regulator, AbiEi antitoxin L21SP4_RS10495 172edaff8212f602f1e2024219953027 392 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 368 389 3.6E-5 T 22-04-2016 IPR013424 PEP-CTERM protein-sorting domain L21SP4_RS10495 172edaff8212f602f1e2024219953027 392 Pfam PF07589 PEP-CTERM motif 367 389 1.9E-4 T 22-04-2016 IPR013424 PEP-CTERM protein-sorting domain L21SP4_RS00555 fb441c654261f037b6b79a011a1ad86e 169 SUPERFAMILY SSF56935 115 169 8.51E-5 T 22-04-2016 L21SP4_RS00555 fb441c654261f037b6b79a011a1ad86e 169 SUPERFAMILY SSF56935 2 81 8.51E-5 T 22-04-2016 L21SP4_RS00180 79607d3adf7c9e15ca8cc158a047b9d6 282 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 198 221 0.0029 T 22-04-2016 IPR013424 PEP-CTERM protein-sorting domain L21SP4_RS11560 fe9f82ee284d5665f502d185a39379cf 281 PANTHER PTHR13773 4 278 7.5E-36 T 22-04-2016 L21SP4_RS11560 fe9f82ee284d5665f502d185a39379cf 281 PANTHER PTHR13773:SF0 4 278 7.5E-36 T 22-04-2016 L21SP4_RS11560 fe9f82ee284d5665f502d185a39379cf 281 Pfam PF01148 Cytidylyltransferase family 5 278 6.8E-42 T 22-04-2016 L21SP4_RS00905 b6b1b40421fcb6712ac5409cc96090a3 197 Pfam PF08843 Nucleotidyl transferase AbiEii toxin, Type IV TA system 9 188 2.2E-12 T 22-04-2016 IPR014942 Nucleotidyl transferase AbiEii toxin, Type IV TA system L21SP4_RS02400 47af903f224da5d6e888628abdc45506 197 Pfam PF02674 Colicin V production protein 13 162 3.4E-14 T 22-04-2016 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 L21SP4_RS00390 5f3ec088b94b8c19dd24c9a79870d8e3 142 Pfam PF02472 Biopolymer transport protein ExbD/TolR 11 136 1.0E-15 T 22-04-2016 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 L21SP4_RS00390 5f3ec088b94b8c19dd24c9a79870d8e3 142 PANTHER PTHR30558 1 135 1.2E-18 T 22-04-2016 L21SP4_RS01100 69ce86dff845878c4316ca93c57d13cf 487 Pfam PF13439 Glycosyltransferase Family 4 17 192 6.1E-7 T 22-04-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain L21SP4_RS01100 69ce86dff845878c4316ca93c57d13cf 487 SUPERFAMILY SSF53756 7 368 7.33E-20 T 22-04-2016 L21SP4_RS09485 7db7718cd82031ada5917aebb53af48b 307 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 283 305 1.4E-5 T 22-04-2016 IPR013424 PEP-CTERM protein-sorting domain L21SP4_RS01360 0bc65bcb2547bd7e8874c34414b914ff 335 SUPERFAMILY SSF53067 173 292 2.99E-5 T 22-04-2016 L21SP4_RS07850 5d4eb6d8a209d4b1e57780b16bb22748 389 Pfam PF10087 Uncharacterized protein conserved in bacteria (DUF2325) 296 385 1.1E-20 T 22-04-2016 IPR016772 Uncharacterised conserved protein UCP020408 L21SP4_RS11000 90a031d2e3274eff17a524b16b4da867 298 TIGRFAM TIGR02597 TIGR02597: TIGR02597 family protein 20 253 3.9E-21 T 22-04-2016 IPR019837 Conserved hypothetical protein CHP02597 L21SP4_RS00340 1d6132bb511449338da475e873a9aabb 342 Pfam PF01699 Sodium/calcium exchanger protein 12 128 5.1E-10 T 22-04-2016 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: REACT_15518 L21SP4_RS00340 1d6132bb511449338da475e873a9aabb 342 Pfam PF01699 Sodium/calcium exchanger protein 196 337 1.2E-14 T 22-04-2016 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: REACT_15518 L21SP4_RS02340 882543bb45115056e70eb4aeaabc1e93 256 Pfam PF02163 Peptidase family M50 112 158 4.8E-7 T 22-04-2016 IPR008915 Peptidase M50 GO:0004222|GO:0006508 L21SP4_RS02340 882543bb45115056e70eb4aeaabc1e93 256 PANTHER PTHR39188 3 195 2.8E-20 T 22-04-2016 L21SP4_RS09475 6f5b1a4b90c86c7c3b12da14bec55ddc 307 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 283 305 1.4E-5 T 22-04-2016 IPR013424 PEP-CTERM protein-sorting domain L21SP4_RS03780 a9eb85da296694c9f3e910eb0489f38b 185 Pfam PF04390 Lipopolysaccharide-assembly 23 179 1.1E-12 T 22-04-2016 IPR007485 LPS-assembly lipoprotein LptE GO:0019867|GO:0043165 L21SP4_RS01820 1abca046eb164dc9c334b5f50140343d 283 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 259 282 6.8E-6 T 22-04-2016 IPR013424 PEP-CTERM protein-sorting domain L21SP4_RS11500 c1801f4c10106a967e71e766f3de6103 175 Pfam PF04306 Protein of unknown function (DUF456) 27 170 3.0E-17 T 22-04-2016 IPR007403 Protein of unknown function DUF456 L21SP4_RS06160 7042ef1953cd6e02bbee8c52c6317fdb 115 TIGRFAM TIGR04073 exo_TIGR04073: putative exosortase-associated protein, TIGR04073 family 23 95 5.3E-23 T 22-04-2016 IPR023824 Conserved hypothetical protein CHP04073, exosortase-affiliated L21SP4_RS00780 30f52eecff0b65b46fceac6f74fc0f0a 174 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 13 33 - T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site L21SP4_RS12175 179bf3df84a07ae0a13659a5f2e7443d 171 Pfam PF13801 Heavy-metal resistance 11 124 7.7E-10 T 22-04-2016 IPR025961 Heavy-metal resistance protein L21SP4_RS03035 5fdd72cc0bea5ecf74c410f7b12f36db 252 Pfam PF08889 WbqC-like protein family 7 224 1.5E-70 T 22-04-2016 IPR014985 WbqC-like protein family L21SP4_RS09915 2be18bb48322ea2db5e7e8710c6de1ff 183 Pfam PF12694 Putative molybdenum carrier 6 156 1.0E-42 T 22-04-2016 IPR024755 Molybdenum cofactor carrier, putative L21SP4_RS06880 52800df80b6b7436983f82221152dc4f 314 Pfam PF12705 PD-(D/E)XK nuclease superfamily 9 309 2.1E-10 T 22-04-2016 L21SP4_RS08220 e81e87ca51f1255b1e2c4efb31d33995 419 Pfam PF01566 Natural resistance-associated macrophage protein 30 386 2.2E-63 T 22-04-2016 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: REACT_15518 L21SP4_RS07810 01fe91a89c27ef67a505c3865127d9df 313 SUPERFAMILY SSF54523 1 92 7.46E-7 T 22-04-2016 L21SP4_RS07460 5c8763a172d232dde222d00c2c7faa7b 306 Pfam PF08843 Nucleotidyl transferase AbiEii toxin, Type IV TA system 35 277 2.1E-43 T 22-04-2016 IPR014942 Nucleotidyl transferase AbiEii toxin, Type IV TA system L21SP4_RS00175 02b5c6eb9b8fd1c398fd8671f6dc7468 175 Pfam PF09622 Putative integral membrane protein (DUF2391) 53 170 4.3E-11 T 22-04-2016 IPR024464 Protein of unknown function DUF2391 L21SP4_RS07880 b7c18c72638665bb1b2f04f1f0891325 88 SUPERFAMILY SSF50037 14 82 4.12E-9 T 22-04-2016 IPR008988 Transcriptional repressor, C-terminal L21SP4_RS07880 b7c18c72638665bb1b2f04f1f0891325 88 Pfam PF04023 FeoA domain 13 83 4.7E-12 T 22-04-2016 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 L21SP4_RS07880 b7c18c72638665bb1b2f04f1f0891325 88 SMART SM00899 12 83 1.5E-6 T 22-04-2016 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 L21SP4_RS00465 62f6ef98f471cc7d58dc8136214261ad 503 Pfam PF13709 Domain of unknown function (DUF4159) 95 279 5.7E-23 T 22-04-2016 IPR025297 Domain of unknown function DUF4159 L21SP4_RS00465 62f6ef98f471cc7d58dc8136214261ad 503 Pfam PF13709 Domain of unknown function (DUF4159) 309 501 7.3E-37 T 22-04-2016 IPR025297 Domain of unknown function DUF4159 L21SP4_RS08250 5fa0a5636fe5efb4f54b4a27a7f86951 299 Gene3D G3DSA:3.30.70.60 185 257 0.001 T 22-04-2016 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 L21SP4_RS10425 a53a6dbf3da227016e619b80eb301346 320 Pfam PF07949 YbbR-like protein 138 218 1.6E-9 T 22-04-2016 IPR012505 YbbR-like L21SP4_RS10425 a53a6dbf3da227016e619b80eb301346 320 Pfam PF07949 YbbR-like protein 248 311 8.1E-5 T 22-04-2016 IPR012505 YbbR-like L21SP4_RS09715 9d7fcf7d92f6181a97668d2ca87c04c6 182 Pfam PF04986 Putative transposase 8 58 5.1E-8 T 22-04-2016 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 L21SP4_RS00240 c604c2b083f23a01fe0b602234fab552 355 Gene3D G3DSA:2.40.160.10 98 282 1.9E-6 T 22-04-2016 IPR023614 Porin domain L21SP4_RS07465 53e89dee84d31f4c4c478c526e40ffde 199 Pfam PF13338 Transcriptional regulator, AbiEi antitoxin 27 99 3.9E-18 T 22-04-2016 IPR025159 Transcriptional regulator, AbiEi antitoxin L21SP4_RS03565 7fcfbdecff0f21c0b020b7f5ee92682f 447 SUPERFAMILY SSF53067 27 147 1.94E-9 T 22-04-2016