locus-tag	class	description
VAB18032_RS00005	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
VAB18032_RS00025	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
VAB18032_RS00085	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
VAB18032_RS00120	COG0789	Transcriptional regulator
VAB18032_RS00130	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
VAB18032_RS00160	COG0517	IMP dehydrogenase activity
VAB18032_RS00165	COG0442	prolyl-tRNA aminoacylation
VAB18032_RS00170	COG2197	response regulator
VAB18032_RS00175	COG4585	Histidine kinase
VAB18032_RS00215	COG0439	Biotin carboxylase
VAB18032_RS00220	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
VAB18032_RS00225	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
VAB18032_RS00230	COG1960	acyl-CoA dehydrogenase activity
VAB18032_RS00240	COG1846	Transcriptional regulator
VAB18032_RS00245	COG2353	YceI-like domain
VAB18032_RS00320	COG1716	ATPase activity
VAB18032_RS00320	COG1716	ATPase activity
VAB18032_RS00325	COG1716	ATPase activity
VAB18032_RS00340	COG0768	penicillin binding
VAB18032_RS00345	COG0515	serine threonine protein kinase
VAB18032_RS00350	COG2815	serine threonine protein kinase
VAB18032_RS00350	COG0515	serine threonine protein kinase
VAB18032_RS00370	COG3764	Sortase (surface protein transpeptidase)
VAB18032_RS00385	COG0247	lactate metabolic process
VAB18032_RS00385	COG2181	nitrate reductase activity
VAB18032_RS00400	COG0717	Belongs to the dCTP deaminase family
VAB18032_RS00420	COG2910	NAD(P)H-binding
VAB18032_RS00425	COG1733	regulation of RNA biosynthetic process
VAB18032_RS00470	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
VAB18032_RS00475	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
VAB18032_RS00485	COG1960	acyl-CoA dehydrogenase activity
VAB18032_RS00495	COG2062	phosphohistidine phosphatase, SixA
VAB18032_RS00510	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
VAB18032_RS00520	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
VAB18032_RS00540	COG0508	dehydrogenase complex catalyzes the overall conversion of
VAB18032_RS00545	COG0022	dehydrogenase e1 component
VAB18032_RS00580	COG0443	Heat shock 70 kDa protein
VAB18032_RS00585	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
VAB18032_RS00590	COG0484	heat shock protein binding
VAB18032_RS00595	COG0789	Transcriptional regulator
VAB18032_RS00615	COG0542	response to heat
VAB18032_RS00645	COG0640	Transcriptional regulator
VAB18032_RS00655	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
VAB18032_RS00670	COG1950	PFAM Membrane protein of
VAB18032_RS00675	COG0191	fructose-bisphosphate aldolase activity
VAB18032_RS00700	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
VAB18032_RS00705	COG0151	Belongs to the GarS family
VAB18032_RS00765	COG0318	PFAM AMP-dependent synthetase and ligase
VAB18032_RS00770	COG1960	acyl-CoA dehydrogenase activity
VAB18032_RS00810	COG2030	dehydratase
VAB18032_RS00815	COG1028	Short-chain dehydrogenase reductase Sdr
VAB18032_RS00820	COG0183	Belongs to the thiolase family
VAB18032_RS00830	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
VAB18032_RS00835	COG0393	Putative heavy-metal-binding
VAB18032_RS00845	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
VAB18032_RS00850	COG0047	phosphoribosylformylglycinamidine synthase activity
VAB18032_RS00855	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
VAB18032_RS00880	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
VAB18032_RS00885	COG0641	radical SAM
VAB18032_RS00900	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
VAB18032_RS00930	COG1250	3-hydroxyacyl-CoA dehydrogenase
VAB18032_RS00935	COG1024	Enoyl-CoA hydratase
VAB18032_RS00980	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
VAB18032_RS00990	COG0142	geranyltranstransferase activity
VAB18032_RS01165	COG1051	belongs to the nudix hydrolase family
VAB18032_RS01195	COG2188	Transcriptional regulator
VAB18032_RS01200	COG2189	Belongs to the N(4) N(6)-methyltransferase family
VAB18032_RS01200	COG2189	Belongs to the N(4) N(6)-methyltransferase family
VAB18032_RS01245	COG1121	(ABC) transporter
VAB18032_RS01260	COG4566	intracellular signal transduction
VAB18032_RS01270	COG3135	benzoate transporter
VAB18032_RS01290	COG2186	Transcriptional regulator
VAB18032_RS01295	COG2807	transmembrane transport
VAB18032_RS01305	COG1366	Belongs to the anti-sigma-factor antagonist family
VAB18032_RS01310	COG1366	Belongs to the anti-sigma-factor antagonist family
VAB18032_RS01315	COG2172	sigma factor antagonist activity
VAB18032_RS01325	COG2205	protein histidine kinase activity
VAB18032_RS01330	COG0745	RESPONSE REGULATOR receiver
VAB18032_RS01360	COG0277	FAD linked oxidase domain protein
VAB18032_RS01370	COG2205	protein histidine kinase activity
VAB18032_RS01370	COG0784	Response regulator, receiver
VAB18032_RS01380	COG1366	Belongs to the anti-sigma-factor antagonist family
VAB18032_RS01385	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
VAB18032_RS01390	COG0406	alpha-ribazole phosphatase activity
VAB18032_RS01395	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
VAB18032_RS01400	COG0785	Cytochrome C biogenesis protein
VAB18032_RS01410	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
VAB18032_RS01420	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
VAB18032_RS01425	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
VAB18032_RS01435	COG0163	prenyltransferase activity
VAB18032_RS01445	COG1522	sequence-specific DNA binding
VAB18032_RS01460	COG0513	Belongs to the DEAD box helicase family
VAB18032_RS01475	COG0791	NLP P60 protein
VAB18032_RS01480	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
VAB18032_RS01500	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
VAB18032_RS01505	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VAB18032_RS01510	COG1120	ATPase activity
VAB18032_RS01530	COG1131	(ABC) transporter
VAB18032_RS01540	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
VAB18032_RS01555	COG3396	Phenylacetate-CoA oxygenase
VAB18032_RS01560	COG3460	Phenylacetate-CoA oxygenase
VAB18032_RS01565	COG3396	Phenylacetate-CoA oxygenase
VAB18032_RS01570	COG2151	metal-sulfur cluster biosynthetic enzyme
VAB18032_RS01575	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
VAB18032_RS01580	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
VAB18032_RS01590	COG2226	methyltransferase
VAB18032_RS01610	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
VAB18032_RS01615	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
VAB18032_RS01620	COG0649	NAD binding
VAB18032_RS01635	COG1034	ATP synthesis coupled electron transport
VAB18032_RS01645	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
VAB18032_RS01655	COG0713	ATP synthesis coupled electron transport
VAB18032_RS01670	COG1007	ATP synthesis coupled electron transport
VAB18032_RS01675	COG0142	geranyltranstransferase activity
VAB18032_RS01715	COG1950	PFAM Membrane protein of
VAB18032_RS01760	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
VAB18032_RS01825	COG1205	dead DEAH box helicase
VAB18032_RS01825	COG1111	helicase
VAB18032_RS01830	COG1366	Belongs to the anti-sigma-factor antagonist family
VAB18032_RS01840	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
VAB18032_RS01855	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
VAB18032_RS01855	COG1754	DNA topoisomerase type I activity
VAB18032_RS01870	COG1309	transcriptional regulator
VAB18032_RS01880	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
VAB18032_RS01885	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
VAB18032_RS01905	COG1774	PSP1 C-terminal conserved region
VAB18032_RS01950	COG0859	PFAM glycosyl transferase family 9
VAB18032_RS01965	COG0693	protein deglycase activity
VAB18032_RS01980	COG1063	alcohol dehydrogenase
VAB18032_RS01985	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VAB18032_RS02000	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
VAB18032_RS02010	COG3285	dna ligase
VAB18032_RS02010	COG1793	dna ligase
VAB18032_RS02035	COG1061	Type III restriction enzyme res subunit
VAB18032_RS02055	COG1278	Cold shock
VAB18032_RS02060	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
VAB18032_RS02065	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
VAB18032_RS02070	COG2814	Major facilitator Superfamily
VAB18032_RS02085	COG2252	PERMEase
VAB18032_RS02095	COG2814	Major facilitator Superfamily
VAB18032_RS02105	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
VAB18032_RS02115	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
VAB18032_RS02125	COG0259	pyridoxamine-phosphate oxidase activity
VAB18032_RS02135	COG2017	converts alpha-aldose to the beta-anomer
VAB18032_RS02160	COG1760	l-serine dehydratase
VAB18032_RS02180	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
VAB18032_RS02185	COG3842	ATPase activity
VAB18032_RS02245	COG1937	Protein conserved in bacteria
VAB18032_RS02265	COG3237	CsbD-like
VAB18032_RS02290	COG3387	PFAM Glycoside hydrolase 15-related
VAB18032_RS02310	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
VAB18032_RS02315	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
VAB18032_RS02320	COG1742	UPF0060 membrane protein
VAB18032_RS02345	COG2837	iron assimilation
VAB18032_RS02370	COG0725	ABC transporter, periplasmic molybdate-binding protein
VAB18032_RS02395	COG2217	Heavy metal translocating P-type atpase
VAB18032_RS02405	COG1595	DNA-templated transcription, initiation
VAB18032_RS02410	COG4941	Belongs to the sigma-70 factor family
VAB18032_RS02430	COG0477	Major facilitator Superfamily
VAB18032_RS02435	COG1012	belongs to the aldehyde dehydrogenase family
VAB18032_RS02460	COG0431	NADPH-dependent FMN reductase
VAB18032_RS02485	COG2124	cytochrome p450
VAB18032_RS02500	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
VAB18032_RS02500	COG3433	isochorismatase activity
VAB18032_RS02500	COG2226	methyltransferase
VAB18032_RS02505	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
VAB18032_RS02525	COG0318	PFAM AMP-dependent synthetase and ligase
VAB18032_RS02530	COG2226	methyltransferase
VAB18032_RS02530	COG2867	negative regulation of translational initiation
VAB18032_RS02540	COG1960	acyl-CoA dehydrogenase activity
VAB18032_RS02545	COG1960	acyl-CoA dehydrogenase activity
VAB18032_RS02550	COG2124	cytochrome p450
VAB18032_RS02570	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
VAB18032_RS02580	COG1012	belongs to the aldehyde dehydrogenase family
VAB18032_RS02590	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
VAB18032_RS02595	COG2124	cytochrome p450
VAB18032_RS02605	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
VAB18032_RS02610	COG1021	2,3-dihydroxybenzoate-AMP ligase
VAB18032_RS02620	COG0183	Belongs to the thiolase family
VAB18032_RS02625	COG1804	L-carnitine dehydratase bile acid-inducible protein F
VAB18032_RS02640	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
VAB18032_RS02645	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
VAB18032_RS02650	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
VAB18032_RS02690	COG0318	PFAM AMP-dependent synthetase and ligase
VAB18032_RS02715	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
VAB18032_RS02735	COG3457	Alanine racemase
VAB18032_RS02740	COG1172	Belongs to the binding-protein-dependent transport system permease family
VAB18032_RS02760	COG1846	Transcriptional regulator
VAB18032_RS02760	COG1940	carbohydrate kinase activity
VAB18032_RS02840	COG3845	ABC transporter
VAB18032_RS02965	COG2823	Periplasmic or secreted lipoprotein
VAB18032_RS03075	COG1196	nuclear chromosome segregation
VAB18032_RS03075	COG0741	lytic transglycosylase activity
VAB18032_RS03075	COG0739	heme binding
VAB18032_RS03160	COG3293	Transposase
VAB18032_RS03200	COG2963	transposase activity
VAB18032_RS03205	COG2801	Transposase and inactivated derivatives
VAB18032_RS03240	COG2801	Transposase and inactivated derivatives
VAB18032_RS03260	COG0154	amidase activity
VAB18032_RS03275	COG0604	alcohol dehydrogenase
VAB18032_RS03275	COG3321	synthase
VAB18032_RS03275	COG1028	Short-chain dehydrogenase reductase Sdr
VAB18032_RS03295	COG0789	Transcriptional regulator
VAB18032_RS03320	COG0010	Belongs to the arginase family
VAB18032_RS03330	COG0110	maltose O-acetyltransferase activity
VAB18032_RS03335	COG4977	sequence-specific DNA binding
VAB18032_RS03355	COG1136	(ABC) transporter
VAB18032_RS03355	COG0577	efflux transmembrane transporter activity
VAB18032_RS03360	COG1136	(ABC) transporter
VAB18032_RS03375	COG0745	RESPONSE REGULATOR receiver
VAB18032_RS03380	COG2205	protein histidine kinase activity
VAB18032_RS03400	COG1309	transcriptional regulator
VAB18032_RS03405	COG0702	epimerase
VAB18032_RS03425	COG3903	Transcriptional regulator
VAB18032_RS03425	COG3629	intracellular signal transduction
VAB18032_RS03460	COG4585	Histidine kinase
VAB18032_RS03465	COG2197	response regulator
VAB18032_RS03480	COG0740	serine-type endopeptidase activity
VAB18032_RS03485	COG1396	sequence-specific DNA binding
VAB18032_RS03490	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
VAB18032_RS03495	COG1013	pyruvate-flavodoxin oxidoreductase activity
VAB18032_RS03500	COG0674	pyruvate-flavodoxin oxidoreductase activity
VAB18032_RS03500	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
VAB18032_RS03505	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
VAB18032_RS03510	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
VAB18032_RS03525	COG0519	Catalyzes the synthesis of GMP from XMP
VAB18032_RS03535	COG1024	Enoyl-CoA hydratase
VAB18032_RS03545	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
VAB18032_RS03550	COG4122	O-methyltransferase activity
VAB18032_RS03555	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
VAB18032_RS03560	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
VAB18032_RS03575	COG2239	Acts as a magnesium transporter
VAB18032_RS03580	COG0384	phenazine biosynthesis protein PhzF
VAB18032_RS03600	COG0454	-acetyltransferase
VAB18032_RS03635	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
VAB18032_RS03660	COG1595	DNA-templated transcription, initiation
VAB18032_RS03670	COG0613	PHP domain protein
VAB18032_RS03675	COG2095	MarC family integral membrane protein
VAB18032_RS03710	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
VAB18032_RS03720	COG1210	Utp--glucose-1-phosphate uridylyltransferase
VAB18032_RS03725	COG0303	'Molybdopterin
VAB18032_RS03760	COG3795	YCII-related domain
VAB18032_RS03765	COG4941	Belongs to the sigma-70 factor family
VAB18032_RS03770	COG1028	Short-chain dehydrogenase reductase Sdr
VAB18032_RS03775	COG1832	CoA-binding protein
VAB18032_RS03785	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
VAB18032_RS03795	COG2072	flavoprotein involved in K transport
VAB18032_RS03800	COG0583	DNA-binding transcription factor activity
VAB18032_RS03810	COG3940	Belongs to the glycosyl hydrolase 43 family
VAB18032_RS03835	COG0395	ABC-type sugar transport system, permease component
VAB18032_RS03840	COG4209	transmembrane transport
VAB18032_RS03890	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VAB18032_RS03895	COG2267	carboxylic ester hydrolase activity
VAB18032_RS03905	COG0084	hydrolase, TatD family'
VAB18032_RS03910	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
VAB18032_RS03915	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
VAB18032_RS03920	COG0488	(ABC) transporter
VAB18032_RS03955	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
VAB18032_RS03960	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
VAB18032_RS03965	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
VAB18032_RS03970	COG0193	aminoacyl-tRNA hydrolase activity
VAB18032_RS03975	COG1218	3'(2'),5'-bisphosphate nucleotidase
VAB18032_RS03990	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
VAB18032_RS03995	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
VAB18032_RS04005	COG0180	Tryptophanyl-tRNA synthetase
VAB18032_RS04025	COG0366	Alpha amylase catalytic
VAB18032_RS04045	COG3833	ABC-type maltose transport systems, permease component
VAB18032_RS04055	COG1744	ABC transporter substrate-binding protein PnrA-like
VAB18032_RS04060	COG3845	ABC transporter
VAB18032_RS04065	COG4603	Belongs to the binding-protein-dependent transport system permease family
VAB18032_RS04070	COG1079	Belongs to the binding-protein-dependent transport system permease family
VAB18032_RS04095	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
VAB18032_RS04110	COG2018	Roadblock/LC7 domain
VAB18032_RS04135	COG1695	Transcriptional regulator
VAB18032_RS04145	COG2274	protein secretion by the type I secretion system
VAB18032_RS04150	COG4988	ABC transporter
VAB18032_RS04160	COG1271	oxidase subunit
VAB18032_RS04175	COG1012	belongs to the aldehyde dehydrogenase family
VAB18032_RS04180	COG1012	belongs to the aldehyde dehydrogenase family
VAB18032_RS04185	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
VAB18032_RS04190	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
VAB18032_RS04200	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
VAB18032_RS04205	COG2815	serine threonine protein kinase
VAB18032_RS04205	COG0515	serine threonine protein kinase
VAB18032_RS04210	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
VAB18032_RS04210	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
VAB18032_RS04215	COG1473	amidohydrolase
VAB18032_RS04215	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
VAB18032_RS04270	COG1846	Transcriptional regulator
VAB18032_RS04290	COG4770	biotin carboxylase activity
VAB18032_RS04315	COG4221	oxidoreductase activity
VAB18032_RS04330	COG4122	O-methyltransferase activity
VAB18032_RS04335	COG0424	maF-like protein
VAB18032_RS04340	COG1404	Belongs to the peptidase S8 family
VAB18032_RS04360	COG0515	serine threonine protein kinase
VAB18032_RS04360	COG2815	serine threonine protein kinase
VAB18032_RS04385	COG1595	DNA-templated transcription, initiation
VAB18032_RS04395	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
VAB18032_RS04420	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
VAB18032_RS04430	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
VAB18032_RS04435	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VAB18032_RS04435	COG0561	phosphatase activity
VAB18032_RS04460	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
VAB18032_RS04505	COG1722	exodeoxyribonuclease VII activity
VAB18032_RS04520	COG1570	exodeoxyribonuclease VII activity
VAB18032_RS04525	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
VAB18032_RS04540	COG1322	Protein conserved in bacteria
VAB18032_RS04550	COG1940	carbohydrate kinase activity
VAB18032_RS04555	COG1840	ABC-type Fe3 transport system, periplasmic component
VAB18032_RS04560	COG3842	ATPase activity
VAB18032_RS04575	COG0165	Argininosuccinate lyase
VAB18032_RS04585	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
VAB18032_RS04620	COG0148	phosphopyruvate hydratase activity
VAB18032_RS04635	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
VAB18032_RS04670	COG3654	unkown
VAB18032_RS04695	COG0714	Associated with various cellular activities
VAB18032_RS04730	COG0183	Belongs to the thiolase family
VAB18032_RS04755	COG0456	acetyltransferase
VAB18032_RS04755	COG0454	-acetyltransferase
VAB18032_RS04760	COG1234	tRNA 3'-trailer cleavage
VAB18032_RS04765	COG1363	Peptidase, m42
VAB18032_RS04770	COG0189	ligase activity
VAB18032_RS04770	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
VAB18032_RS04775	COG0367	asparagine synthase
VAB18032_RS04780	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VAB18032_RS04785	COG0537	adenosine 5'-monophosphoramidase activity
VAB18032_RS04805	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
VAB18032_RS04810	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VAB18032_RS04820	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
VAB18032_RS04835	COG1331	Highly conserved protein containing a thioredoxin domain
VAB18032_RS04865	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
VAB18032_RS04880	COG1607	acyl-coa hydrolase
VAB18032_RS04885	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
VAB18032_RS04895	COG0438	transferase activity, transferring glycosyl groups
VAB18032_RS04900	COG0662	Cupin 2, conserved barrel domain protein
VAB18032_RS04900	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
VAB18032_RS04920	COG0391	Required for morphogenesis under gluconeogenic growth conditions
VAB18032_RS04930	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
VAB18032_RS04965	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
VAB18032_RS04970	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
VAB18032_RS04995	COG3842	ATPase activity
VAB18032_RS05000	COG1176	ABC-type spermidine putrescine transport system, permease component I
VAB18032_RS05005	COG1177	transmembrane transport
VAB18032_RS05030	COG0745	RESPONSE REGULATOR receiver
VAB18032_RS05035	COG2205	protein histidine kinase activity
VAB18032_RS05050	COG1181	Belongs to the D-alanine--D-alanine ligase family
VAB18032_RS05070	COG1012	belongs to the aldehyde dehydrogenase family
VAB18032_RS05075	COG1012	belongs to the aldehyde dehydrogenase family
VAB18032_RS05100	COG2318	DinB family
VAB18032_RS05110	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
VAB18032_RS05115	COG2835	tetraacyldisaccharide 4'-kinase activity
VAB18032_RS05130	COG1482	cell wall glycoprotein biosynthetic process
VAB18032_RS05135	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
VAB18032_RS05155	COG0714	Associated with various cellular activities
VAB18032_RS05175	COG0745	RESPONSE REGULATOR receiver
VAB18032_RS05180	COG5002	protein histidine kinase activity
VAB18032_RS05195	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
VAB18032_RS05210	COG0653	protein targeting
VAB18032_RS05235	COG1012	belongs to the aldehyde dehydrogenase family
VAB18032_RS05245	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
VAB18032_RS05250	COG2884	Cell division ATP-binding protein ftsE
VAB18032_RS05255	COG2177	Part of the ABC transporter FtsEX involved in
VAB18032_RS05260	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
VAB18032_RS05275	COG1678	Uncharacterized ACR, COG1678
VAB18032_RS05310	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
VAB18032_RS05345	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
VAB18032_RS05375	COG0789	Transcriptional regulator
VAB18032_RS05395	COG4941	Belongs to the sigma-70 factor family
VAB18032_RS05405	COG3795	YCII-related domain
VAB18032_RS05415	COG2814	Major facilitator Superfamily
VAB18032_RS05475	COG0543	2 iron, 2 sulfur cluster binding
VAB18032_RS05475	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
VAB18032_RS05550	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
VAB18032_RS05560	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
VAB18032_RS05575	COG0656	L-ascorbic acid biosynthetic process
VAB18032_RS05580	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
VAB18032_RS05630	COG2197	response regulator
VAB18032_RS05655	COG2234	aminopeptidase activity
VAB18032_RS05710	COG2205	protein histidine kinase activity
VAB18032_RS05715	COG0745	RESPONSE REGULATOR receiver
VAB18032_RS05735	COG3387	PFAM Glycoside hydrolase 15-related
VAB18032_RS05760	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VAB18032_RS05765	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
VAB18032_RS05775	COG1335	isochorismatase
VAB18032_RS05780	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
VAB18032_RS05785	COG2197	response regulator
VAB18032_RS05795	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
VAB18032_RS05820	COG1234	tRNA 3'-trailer cleavage
VAB18032_RS05825	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
VAB18032_RS05830	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
VAB18032_RS05835	COG2986	histidine ammonia-lyase
VAB18032_RS05840	COG1228	amidohydrolase
VAB18032_RS05845	COG0402	S-adenosylhomocysteine deaminase activity
VAB18032_RS05850	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
VAB18032_RS05855	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
VAB18032_RS05875	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
VAB18032_RS05875	COG2755	lipolytic protein G-D-S-L family
VAB18032_RS05905	COG1316	TRANSCRIPTIONal
VAB18032_RS05940	COG0310	cobalt ion transport
VAB18032_RS05955	COG1122	ATPase activity
VAB18032_RS05965	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
VAB18032_RS05995	COG5650	phosphatidylinositol metabolic process
VAB18032_RS06000	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
VAB18032_RS06015	COG0747	negative chemotaxis
VAB18032_RS06020	COG0601	transmembrane transport
VAB18032_RS06025	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VAB18032_RS06035	COG0596	Alpha beta hydrolase
VAB18032_RS06045	COG4608	Belongs to the ABC transporter superfamily
VAB18032_RS06060	COG1376	ErfK ybiS ycfS ynhG family protein
VAB18032_RS06065	COG1376	ErfK ybiS ycfS ynhG family protein
VAB18032_RS06075	COG1819	glycosyl
VAB18032_RS06100	COG1216	Glycosyl transferase, family 2
VAB18032_RS06105	COG1132	(ABC) transporter
VAB18032_RS06115	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
VAB18032_RS06185	COG1216	Glycosyl transferase, family 2
VAB18032_RS06200	COG3903	Transcriptional regulator
VAB18032_RS06200	COG3629	intracellular signal transduction
VAB18032_RS06205	COG1215	transferase activity, transferring glycosyl groups
VAB18032_RS06220	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
VAB18032_RS06225	COG0297	glycogen (starch) synthase activity
VAB18032_RS06230	COG0656	L-ascorbic acid biosynthetic process
VAB18032_RS06240	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
VAB18032_RS06245	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
VAB18032_RS06250	COG1116	anion transmembrane transporter activity
VAB18032_RS06275	COG1028	Short-chain dehydrogenase reductase Sdr
VAB18032_RS06295	COG1414	Transcriptional regulator
VAB18032_RS06330	COG0596	Alpha beta hydrolase
VAB18032_RS06400	COG1131	(ABC) transporter
VAB18032_RS06405	COG1119	ATPase activity
VAB18032_RS06410	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VAB18032_RS06415	COG4977	sequence-specific DNA binding
VAB18032_RS06465	COG2149	membrane
VAB18032_RS06485	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
VAB18032_RS06495	COG1595	DNA-templated transcription, initiation
VAB18032_RS06515	COG0482	sulfurtransferase activity
VAB18032_RS06535	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
VAB18032_RS06545	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
VAB18032_RS06550	COG0154	amidase activity
VAB18032_RS06560	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
VAB18032_RS06565	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
VAB18032_RS06575	COG2133	pyrroloquinoline quinone binding
VAB18032_RS06595	COG1609	Transcriptional regulator
VAB18032_RS06630	COG0659	secondary active sulfate transmembrane transporter activity
VAB18032_RS06640	COG0129	dihydroxy-acid dehydratase activity
VAB18032_RS06655	COG0440	acetolactate synthase activity
VAB18032_RS06660	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
VAB18032_RS06665	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
VAB18032_RS06680	COG0473	3-isopropylmalate dehydrogenase activity
VAB18032_RS06685	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
VAB18032_RS06700	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
VAB18032_RS06715	COG0714	Associated with various cellular activities
VAB18032_RS06725	COG2304	oxidoreductase activity
VAB18032_RS06740	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
VAB18032_RS06760	COG0179	Fumarylacetoacetate (FAA) hydrolase
VAB18032_RS06785	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
VAB18032_RS06790	COG0066	3-isopropylmalate dehydratase activity
VAB18032_RS06795	COG0776	regulation of translation
VAB18032_RS06810	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
VAB18032_RS06820	COG1920	GTP binding
VAB18032_RS06830	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
VAB18032_RS06835	COG0626	cystathionine gamma-synthase activity
VAB18032_RS06840	COG2890	protein-(glutamine-N5) methyltransferase activity
VAB18032_RS06845	COG1940	carbohydrate kinase activity
VAB18032_RS06890	COG0227	Belongs to the bacterial ribosomal protein bL28 family
VAB18032_RS06910	COG0742	ribosomal rna small subunit methyltransferase
VAB18032_RS06915	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
VAB18032_RS06930	COG0333	Belongs to the bacterial ribosomal protein bL32 family
VAB18032_RS06935	COG0416	fatty acid biosynthetic process
VAB18032_RS06940	COG0571	ribonuclease III activity
VAB18032_RS06945	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
VAB18032_RS06955	COG2340	Cysteine-rich secretory protein family
VAB18032_RS06975	COG2318	DinB family
VAB18032_RS06990	COG1846	Transcriptional regulator
VAB18032_RS07020	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
VAB18032_RS07035	COG0442	prolyl-tRNA aminoacylation
VAB18032_RS07045	COG0228	four-way junction DNA binding
VAB18032_RS07050	COG1837	Belongs to the UPF0109 family
VAB18032_RS07055	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
VAB18032_RS07060	COG0336	Belongs to the RNA methyltransferase TrmD family
VAB18032_RS07065	COG0335	large ribosomal subunit rRNA binding
VAB18032_RS07070	COG0681	Belongs to the peptidase S26 family
VAB18032_RS07075	COG0681	Belongs to the peptidase S26 family
VAB18032_RS07085	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
VAB18032_RS07100	COG0156	8-amino-7-oxononanoate synthase activity
VAB18032_RS07105	COG4974	Belongs to the 'phage' integrase family
VAB18032_RS07120	COG0792	nuclease activity
VAB18032_RS07130	COG0052	Belongs to the universal ribosomal protein uS2 family
VAB18032_RS07135	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
VAB18032_RS07140	COG0528	UMP kinase activity
VAB18032_RS07145	COG0233	cytoplasmic translational termination
VAB18032_RS07150	COG0575	Belongs to the CDS family
VAB18032_RS07155	COG0820	rRNA (adenine-C2-)-methyltransferase activity
VAB18032_RS07170	COG2146	nitrite reductase [NAD(P)H] activity
VAB18032_RS07170	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
VAB18032_RS07200	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VAB18032_RS07205	COG1515	deoxyribonuclease V activity
VAB18032_RS07215	COG0750	zinc metalloprotease
VAB18032_RS07220	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
VAB18032_RS07235	COG1902	pentaerythritol trinitrate reductase activity
VAB18032_RS07245	COG0435	Glutathione S-transferase
VAB18032_RS07250	COG0183	Belongs to the thiolase family
VAB18032_RS07310	COG1846	Transcriptional regulator
VAB18032_RS07315	COG0789	Transcriptional regulator
VAB18032_RS07345	COG1012	belongs to the aldehyde dehydrogenase family
VAB18032_RS07385	COG1136	(ABC) transporter
VAB18032_RS07385	COG0577	efflux transmembrane transporter activity
VAB18032_RS07405	COG0779	Required for maturation of 30S ribosomal subunits
VAB18032_RS07415	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
VAB18032_RS07425	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
VAB18032_RS07430	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
VAB18032_RS07455	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
VAB18032_RS07465	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
VAB18032_RS07470	COG1185	polyribonucleotide nucleotidyltransferase activity
VAB18032_RS07475	COG0612	Peptidase, M16
VAB18032_RS07480	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
VAB18032_RS07500	COG3214	Protein conserved in bacteria
VAB18032_RS07510	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
VAB18032_RS07515	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
VAB18032_RS07520	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
VAB18032_RS07540	COG1674	ftsk spoiiie
VAB18032_RS07560	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
VAB18032_RS07570	COG1546	Belongs to the CinA family
VAB18032_RS07570	COG1058	Belongs to the CinA family
VAB18032_RS07580	COG1842	Phage shock protein A
VAB18032_RS07590	COG2132	Multicopper oxidase
VAB18032_RS07595	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
VAB18032_RS07600	COG4991	sh3 domain protein
VAB18032_RS07620	COG1201	RNA secondary structure unwinding
VAB18032_RS07630	COG2111	Na H antiporter
VAB18032_RS07630	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
VAB18032_RS07635	COG1006	Multisubunit Na H antiporter MnhC subunit
VAB18032_RS07640	COG0651	ATP synthesis coupled electron transport
VAB18032_RS07650	COG2212	antiporter activity
VAB18032_RS07655	COG1320	monovalent cation:proton antiporter activity
VAB18032_RS07665	COG1253	flavin adenine dinucleotide binding
VAB18032_RS07670	COG4326	sporulation control protein
VAB18032_RS07690	COG1573	uracil-dna glycosylase
VAB18032_RS07695	COG0477	Major facilitator Superfamily
VAB18032_RS07705	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
VAB18032_RS07705	COG1372	Participates in initiation and elongation during chromosome replication
VAB18032_RS07710	COG2137	regulation of response to DNA damage stimulus
VAB18032_RS07720	COG1418	mRNA catabolic process
VAB18032_RS07735	COG3409	Peptidoglycan-binding domain 1 protein
VAB18032_RS07740	COG1136	(ABC) transporter
VAB18032_RS07740	COG0577	efflux transmembrane transporter activity
VAB18032_RS07745	COG1136	(ABC) transporter
VAB18032_RS07765	COG0765	amino acid transport
VAB18032_RS07770	COG0765	amino acid transport
VAB18032_RS07775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VAB18032_RS07780	COG1126	abc transporter atp-binding protein
VAB18032_RS07800	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
VAB18032_RS07810	COG1196	nuclear chromosome segregation
VAB18032_RS07820	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
VAB18032_RS07825	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
VAB18032_RS07835	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
VAB18032_RS07850	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
VAB18032_RS07855	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
VAB18032_RS07940	COG1490	D-aminoacyl-tRNA deacylase activity
VAB18032_RS07955	COG3842	ATPase activity
VAB18032_RS07960	COG1178	ABC-type Fe3 transport system permease component
VAB18032_RS07965	COG1840	ABC-type Fe3 transport system, periplasmic component
VAB18032_RS08000	COG2313	pseudouridylate synthase activity
VAB18032_RS08010	COG2860	membrane
VAB18032_RS08030	COG0483	inositol monophosphate 1-phosphatase activity
VAB18032_RS08055	COG0756	dUTP diphosphatase activity
VAB18032_RS08080	COG0569	domain protein
VAB18032_RS08085	COG0531	amino acid
VAB18032_RS08090	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
VAB18032_RS08095	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
VAB18032_RS08130	COG0745	RESPONSE REGULATOR receiver
VAB18032_RS08135	COG2205	protein histidine kinase activity
VAB18032_RS08165	COG1250	3-hydroxyacyl-CoA dehydrogenase
VAB18032_RS08165	COG1024	Enoyl-CoA hydratase
VAB18032_RS08170	COG0183	Belongs to the thiolase family
VAB18032_RS08175	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
VAB18032_RS08185	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
VAB18032_RS08190	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
VAB18032_RS08195	COG3253	May function as heme-dependent peroxidase
VAB18032_RS08230	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VAB18032_RS08235	COG1793	dna ligase
VAB18032_RS08235	COG3285	dna ligase
VAB18032_RS08285	COG1793	dna ligase
VAB18032_RS08300	COG0438	transferase activity, transferring glycosyl groups
VAB18032_RS08305	COG0438	transferase activity, transferring glycosyl groups
VAB18032_RS08315	COG0438	transferase activity, transferring glycosyl groups
VAB18032_RS08345	COG0419	ATPase involved in DNA repair
VAB18032_RS08350	COG0420	3'-5' exonuclease activity
VAB18032_RS08380	COG1175	transmembrane transport
VAB18032_RS08385	COG0395	ABC-type sugar transport system, permease component
VAB18032_RS08400	COG1960	acyl-CoA dehydrogenase activity
VAB18032_RS08440	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
VAB18032_RS08450	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
VAB18032_RS08460	COG2264	protein methyltransferase activity
VAB18032_RS08500	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VAB18032_RS08535	COG0726	polysaccharide deacetylase
VAB18032_RS08550	COG1609	Transcriptional regulator
VAB18032_RS08555	COG1609	Transcriptional regulator
VAB18032_RS08595	COG0589	response to stress
VAB18032_RS08615	COG0542	response to heat
VAB18032_RS08620	COG1597	lipid kinase activity
VAB18032_RS08620	COG1803	Methylglyoxal synthase
VAB18032_RS08630	COG0671	phosphoesterase, PA-phosphatase related
VAB18032_RS08650	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
VAB18032_RS08660	COG4326	sporulation control protein
VAB18032_RS08675	COG3973	AAA domain
VAB18032_RS08800	COG2226	methyltransferase
VAB18032_RS08855	COG0024	Methionine aminopeptidase
VAB18032_RS08860	COG2814	Major facilitator Superfamily
VAB18032_RS08865	COG0831	urea catabolic process
VAB18032_RS08870	COG0832	Belongs to the urease beta subunit family
VAB18032_RS08885	COG0830	nickel cation binding
VAB18032_RS08900	COG4413	Urea transporter
VAB18032_RS08910	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
VAB18032_RS08910	COG0456	acetyltransferase
VAB18032_RS08915	COG1278	Cold shock
VAB18032_RS08920	COG0257	Belongs to the bacterial ribosomal protein bL36 family
VAB18032_RS08930	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
VAB18032_RS08945	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VAB18032_RS08945	COG0425	Belongs to the sulfur carrier protein TusA family
VAB18032_RS08950	COG1937	Protein conserved in bacteria
VAB18032_RS08955	COG0454	-acetyltransferase
VAB18032_RS08955	COG0456	acetyltransferase
VAB18032_RS08960	COG0439	Biotin carboxylase
VAB18032_RS08970	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
VAB18032_RS08990	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
VAB18032_RS08995	COG0247	lactate metabolic process
VAB18032_RS09000	COG1139	Iron-sulfur cluster binding protein
VAB18032_RS09005	COG1556	Lactate utilization protein
VAB18032_RS09020	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VAB18032_RS09035	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
VAB18032_RS09035	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
VAB18032_RS09045	COG0586	Pfam SNARE associated Golgi protein
VAB18032_RS09070	COG3304	Inner membrane component domain
VAB18032_RS09105	COG1120	ATPase activity
VAB18032_RS09155	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
VAB18032_RS09155	COG1017	nitric oxide dioxygenase activity
VAB18032_RS09160	COG1959	2 iron, 2 sulfur cluster binding
VAB18032_RS09170	COG1372	Participates in initiation and elongation during chromosome replication
VAB18032_RS09170	COG0187	DNA topoisomerase II activity
VAB18032_RS09175	COG1372	Participates in initiation and elongation during chromosome replication
VAB18032_RS09175	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
VAB18032_RS09185	COG2233	PERMEase
VAB18032_RS09200	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
VAB18032_RS09220	COG1086	Polysaccharide biosynthesis protein
VAB18032_RS09240	COG1028	Short-chain dehydrogenase reductase Sdr
VAB18032_RS09250	COG2089	acid synthase
VAB18032_RS09255	COG1216	Glycosyl transferase, family 2
VAB18032_RS09295	COG1134	teichoic acid transport
VAB18032_RS09295	COG1388	LysM domain
VAB18032_RS09305	COG1309	transcriptional regulator
VAB18032_RS09320	COG0745	RESPONSE REGULATOR receiver
VAB18032_RS09325	COG0642	Histidine kinase
VAB18032_RS09340	COG3022	response to hydroperoxide
VAB18032_RS09355	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
VAB18032_RS09360	COG0366	Alpha amylase catalytic
VAB18032_RS09370	COG1053	succinate dehydrogenase
VAB18032_RS09395	COG0297	glycogen (starch) synthase activity
VAB18032_RS09400	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
VAB18032_RS09410	COG1086	Polysaccharide biosynthesis protein
VAB18032_RS09440	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
VAB18032_RS09445	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
VAB18032_RS09450	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
VAB18032_RS09460	COG2183	response to ionizing radiation
VAB18032_RS09465	COG0232	Belongs to the dGTPase family. Type 2 subfamily
VAB18032_RS09490	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
VAB18032_RS09495	COG1053	succinate dehydrogenase
VAB18032_RS09505	COG0583	DNA-binding transcription factor activity
VAB18032_RS09510	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VAB18032_RS09515	COG1643	Atp-dependent helicase
VAB18032_RS09545	COG0220	tRNA (guanine-N7-)-methyltransferase activity
VAB18032_RS09590	COG1012	belongs to the aldehyde dehydrogenase family
VAB18032_RS09595	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
VAB18032_RS09615	COG0596	Alpha beta hydrolase
VAB18032_RS09660	COG0667	Aldo Keto reductase
VAB18032_RS09665	COG0137	argininosuccinate synthase activity
VAB18032_RS09670	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
VAB18032_RS09680	COG1741	Belongs to the pirin family
VAB18032_RS09705	COG1233	COG1233 Phytoene dehydrogenase and related
VAB18032_RS09755	COG1012	belongs to the aldehyde dehydrogenase family
VAB18032_RS09765	COG0463	Glycosyl transferase, family 2
VAB18032_RS09775	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
VAB18032_RS09785	COG0297	glycogen (starch) synthase activity
VAB18032_RS09790	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
VAB18032_RS09795	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
VAB18032_RS09795	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
VAB18032_RS09805	COG0859	PFAM glycosyl transferase family 9
VAB18032_RS09840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
VAB18032_RS09845	COG1472	Belongs to the glycosyl hydrolase 3 family
VAB18032_RS09885	COG1278	Cold shock
VAB18032_RS09895	COG0667	Aldo Keto reductase
VAB18032_RS09900	COG4106	trans-aconitate 2-methyltransferase activity
VAB18032_RS09905	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
VAB18032_RS09930	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
VAB18032_RS09955	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
VAB18032_RS09960	COG1560	Kdo2-lipid A biosynthetic process
VAB18032_RS09965	COG0438	transferase activity, transferring glycosyl groups
VAB18032_RS09975	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
VAB18032_RS09980	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
VAB18032_RS09995	COG0217	transcriptional regulatory protein
VAB18032_RS10055	COG4152	abc transporter atp-binding protein
VAB18032_RS10060	COG2197	response regulator
VAB18032_RS10065	COG4585	Histidine kinase
VAB18032_RS10070	COG0501	Belongs to the peptidase M48B family
VAB18032_RS10075	COG1704	LemA family
VAB18032_RS10090	COG1309	transcriptional regulator
VAB18032_RS10100	COG0587	DNA-directed DNA polymerase activity
VAB18032_RS10120	COG0477	Major facilitator Superfamily
VAB18032_RS10125	COG1309	transcriptional regulator
VAB18032_RS10130	COG0586	Pfam SNARE associated Golgi protein
VAB18032_RS10140	COG1028	Short-chain dehydrogenase reductase Sdr
VAB18032_RS10145	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
VAB18032_RS10150	COG0632	four-way junction helicase activity
VAB18032_RS10155	COG2255	four-way junction helicase activity
VAB18032_RS10160	COG1862	Preprotein translocase
VAB18032_RS10170	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VAB18032_RS10175	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
VAB18032_RS10180	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
VAB18032_RS10185	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
VAB18032_RS10200	COG0124	histidyl-tRNA synthetase
VAB18032_RS10225	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
VAB18032_RS10230	COG1091	dTDP-4-dehydrorhamnose reductase activity
VAB18032_RS10275	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
VAB18032_RS10280	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
VAB18032_RS10295	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
VAB18032_RS10350	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
VAB18032_RS10355	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
VAB18032_RS10370	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
VAB18032_RS10375	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
VAB18032_RS10380	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
VAB18032_RS10385	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
VAB18032_RS10395	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
VAB18032_RS10400	COG0540	Belongs to the ATCase OTCase family
VAB18032_RS10405	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
VAB18032_RS10410	COG0505	Belongs to the CarA family
VAB18032_RS10420	COG0167	dihydroorotate dehydrogenase activity
VAB18032_RS10425	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
VAB18032_RS10430	COG0284	orotidine-5'-phosphate decarboxylase activity
VAB18032_RS10440	COG0194	GDP metabolic process
VAB18032_RS10445	COG1758	RNA polymerase activity
VAB18032_RS10455	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
VAB18032_RS10465	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
VAB18032_RS10470	COG2124	cytochrome p450
VAB18032_RS10475	COG0242	peptide deformylase activity
VAB18032_RS10480	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
VAB18032_RS10505	COG0745	RESPONSE REGULATOR receiver
VAB18032_RS10520	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
VAB18032_RS10520	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
VAB18032_RS10525	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
VAB18032_RS10540	COG0765	amino acid transport
VAB18032_RS10545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VAB18032_RS10550	COG0140	phosphoribosyl-ATP diphosphatase activity
VAB18032_RS10555	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
VAB18032_RS10565	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
VAB18032_RS10570	COG0291	Belongs to the bacterial ribosomal protein bL35 family
VAB18032_RS10575	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
VAB18032_RS10580	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
VAB18032_RS10585	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
VAB18032_RS10590	COG0072	phenylalanine-tRNA ligase activity
VAB18032_RS10590	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VAB18032_RS10595	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
VAB18032_RS10615	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
VAB18032_RS10625	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
VAB18032_RS10630	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
VAB18032_RS10635	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
VAB18032_RS10640	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
VAB18032_RS10645	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
VAB18032_RS10655	COG1438	arginine binding
VAB18032_RS10660	COG0165	Argininosuccinate lyase
VAB18032_RS10675	COG2094	Belongs to the DNA glycosylase MPG family
VAB18032_RS10680	COG3152	Membrane
VAB18032_RS10685	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
VAB18032_RS10690	COG0431	NADPH-dependent FMN reductase
VAB18032_RS10705	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
VAB18032_RS10720	COG1253	flavin adenine dinucleotide binding
VAB18032_RS10735	COG1914	H( )-stimulated, divalent metal cation uptake system
VAB18032_RS10745	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
VAB18032_RS10775	COG0647	UMP catabolic process
VAB18032_RS10800	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
VAB18032_RS10830	COG0297	glycogen (starch) synthase activity
VAB18032_RS10840	COG0504	CTP synthase activity
VAB18032_RS10845	COG0494	nUDIX hydrolase
VAB18032_RS10870	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
VAB18032_RS10875	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
VAB18032_RS10880	COG1187	pseudouridine synthase activity
VAB18032_RS10890	COG1160	GTP binding
VAB18032_RS10965	COG2801	Transposase and inactivated derivatives
VAB18032_RS11005	COG0542	response to heat
VAB18032_RS11055	COG3845	ABC transporter
VAB18032_RS11070	COG2079	MmgE PrpD family protein
VAB18032_RS11075	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
VAB18032_RS11085	COG1024	Enoyl-CoA hydratase
VAB18032_RS11155	COG1434	Gram-negative-bacterium-type cell wall biogenesis
VAB18032_RS11170	COG0641	radical SAM
VAB18032_RS11360	COG2801	Transposase and inactivated derivatives
VAB18032_RS11405	COG2801	Transposase and inactivated derivatives
VAB18032_RS11410	COG2963	transposase activity
VAB18032_RS11495	COG0076	glutamate decarboxylase activity
VAB18032_RS11560	COG1518	maintenance of DNA repeat elements
VAB18032_RS11590	COG0395	ABC-type sugar transport system, permease component
VAB18032_RS11595	COG4209	transmembrane transport
VAB18032_RS11625	COG0492	ferredoxin-NADP+ reductase activity
VAB18032_RS11630	COG1028	Short-chain dehydrogenase reductase Sdr
VAB18032_RS11645	COG1607	acyl-coa hydrolase
VAB18032_RS11650	COG1280	lysine exporter protein (LysE YggA)
VAB18032_RS11660	COG2175	clavaminate synthase activity
VAB18032_RS11675	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
VAB18032_RS11685	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
VAB18032_RS11695	COG3321	synthase
VAB18032_RS11695	COG1028	Short-chain dehydrogenase reductase Sdr
VAB18032_RS11695	COG0604	alcohol dehydrogenase
VAB18032_RS11705	COG0431	NADPH-dependent FMN reductase
VAB18032_RS11715	COG2124	cytochrome p450
VAB18032_RS11720	COG4172	Belongs to the ABC transporter superfamily
VAB18032_RS11725	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VAB18032_RS11735	COG0747	negative chemotaxis
VAB18032_RS11740	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
VAB18032_RS11745	COG2814	Major facilitator Superfamily
VAB18032_RS11755	COG3321	synthase
VAB18032_RS11755	COG0604	alcohol dehydrogenase
VAB18032_RS11790	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
VAB18032_RS11820	COG3629	intracellular signal transduction
VAB18032_RS11825	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
VAB18032_RS11850	COG4948	Mandelate Racemase Muconate Lactonizing
VAB18032_RS11860	COG1172	Belongs to the binding-protein-dependent transport system permease family
VAB18032_RS11865	COG1172	Belongs to the binding-protein-dependent transport system permease family
VAB18032_RS11870	COG1129	ABC transporter
VAB18032_RS11875	COG2376	Dihydroxyacetone kinase
VAB18032_RS11880	COG1461	Dihydroxyacetone kinase
VAB18032_RS11890	COG2186	Transcriptional regulator
VAB18032_RS11905	COG0693	protein deglycase activity
VAB18032_RS11930	COG1136	(ABC) transporter
VAB18032_RS11930	COG0577	efflux transmembrane transporter activity
VAB18032_RS11935	COG1136	(ABC) transporter
VAB18032_RS11960	COG0254	rRNA binding
VAB18032_RS11970	COG0745	RESPONSE REGULATOR receiver
VAB18032_RS11975	COG0227	Belongs to the bacterial ribosomal protein bL28 family
VAB18032_RS11980	COG0267	Belongs to the bacterial ribosomal protein bL33 family
VAB18032_RS11985	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
VAB18032_RS12005	COG0803	Belongs to the bacterial solute-binding protein 9 family
VAB18032_RS12015	COG1121	(ABC) transporter
VAB18032_RS12020	COG1108	ABC-type Mn2 Zn2 transport systems permease components
VAB18032_RS12045	COG2801	Transposase and inactivated derivatives
VAB18032_RS12100	COG1309	transcriptional regulator
VAB18032_RS12150	COG1733	regulation of RNA biosynthetic process
VAB18032_RS12155	COG0604	alcohol dehydrogenase
VAB18032_RS12155	COG1028	Short-chain dehydrogenase reductase Sdr
VAB18032_RS12155	COG3321	synthase
VAB18032_RS12165	COG1028	Short-chain dehydrogenase reductase Sdr
VAB18032_RS12245	COG0667	Aldo Keto reductase
VAB18032_RS12275	COG1028	Short-chain dehydrogenase reductase Sdr
VAB18032_RS12275	COG0604	alcohol dehydrogenase
VAB18032_RS12275	COG3321	synthase
VAB18032_RS12310	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
VAB18032_RS12325	COG0477	Major facilitator Superfamily
VAB18032_RS12330	COG2084	Dehydrogenase
VAB18032_RS12340	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
VAB18032_RS12345	COG2124	cytochrome p450
VAB18032_RS12375	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
VAB18032_RS12380	COG4319	ketosteroid isomerase
VAB18032_RS12390	COG3321	synthase
VAB18032_RS12390	COG3321	synthase
VAB18032_RS12390	COG0604	alcohol dehydrogenase
VAB18032_RS12390	COG0604	alcohol dehydrogenase
VAB18032_RS12395	COG3321	synthase
VAB18032_RS12395	COG0604	alcohol dehydrogenase
VAB18032_RS12445	COG2197	response regulator
VAB18032_RS12475	COG1253	flavin adenine dinucleotide binding
VAB18032_RS12580	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
VAB18032_RS12605	COG2226	methyltransferase
VAB18032_RS12630	COG1028	Short-chain dehydrogenase reductase Sdr
VAB18032_RS12635	COG0679	Auxin Efflux Carrier
VAB18032_RS12645	COG1595	DNA-templated transcription, initiation
VAB18032_RS12705	COG1454	alcohol dehydrogenase
VAB18032_RS12715	COG3842	ATPase activity
VAB18032_RS12720	COG3842	ATPase activity
VAB18032_RS12730	COG1175	transmembrane transport
VAB18032_RS12745	COG0693	protein deglycase activity
VAB18032_RS12760	COG1309	transcriptional regulator
VAB18032_RS12765	COG1131	(ABC) transporter
VAB18032_RS12770	COG3559	Exporter of polyketide antibiotics
VAB18032_RS12785	COG2815	serine threonine protein kinase
VAB18032_RS12785	COG0515	serine threonine protein kinase
VAB18032_RS12795	COG1063	alcohol dehydrogenase
VAB18032_RS12820	COG0673	inositol 2-dehydrogenase activity
VAB18032_RS12825	COG2197	response regulator
VAB18032_RS12885	COG1278	Cold shock
VAB18032_RS12890	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VAB18032_RS12895	COG1028	Short-chain dehydrogenase reductase Sdr
VAB18032_RS12900	COG3387	PFAM Glycoside hydrolase 15-related
VAB18032_RS12915	COG1960	acyl-CoA dehydrogenase activity
VAB18032_RS12920	COG1960	acyl-CoA dehydrogenase activity
VAB18032_RS12950	COG1028	Short-chain dehydrogenase reductase Sdr
VAB18032_RS12960	COG1960	acyl-CoA dehydrogenase activity
VAB18032_RS13010	COG1960	acyl-CoA dehydrogenase activity
VAB18032_RS13015	COG1960	acyl-CoA dehydrogenase activity
VAB18032_RS13030	COG0488	(ABC) transporter
VAB18032_RS13050	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
VAB18032_RS13055	COG4569	acetaldehyde dehydrogenase (acetylating) activity
VAB18032_RS13060	COG3971	2-oxopent-4-enoate hydratase activity
VAB18032_RS13075	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
VAB18032_RS13100	COG1414	Transcriptional regulator
VAB18032_RS13105	COG0028	Belongs to the TPP enzyme family
VAB18032_RS13120	COG0318	PFAM AMP-dependent synthetase and ligase
VAB18032_RS13145	COG2030	dehydratase
VAB18032_RS13165	COG0515	serine threonine protein kinase
VAB18032_RS13200	COG0714	Associated with various cellular activities
VAB18032_RS13205	COG3552	Protein containing von Willebrand factor type A (VWA) domain
VAB18032_RS13250	COG2746	aminoglycoside 3-N-acetyltransferase activity
VAB18032_RS13265	COG0531	amino acid
VAB18032_RS13270	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VAB18032_RS13275	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
VAB18032_RS13280	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
VAB18032_RS13310	COG0439	Biotin carboxylase
VAB18032_RS13315	COG0511	ligase activity, forming carbon-carbon bonds
VAB18032_RS13330	COG2867	negative regulation of translational initiation
VAB18032_RS13335	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
VAB18032_RS13345	COG0367	asparagine synthase
VAB18032_RS13355	COG0577	efflux transmembrane transporter activity
VAB18032_RS13355	COG1136	(ABC) transporter
VAB18032_RS13370	COG1271	oxidase subunit
VAB18032_RS13375	COG4585	Histidine kinase
VAB18032_RS13380	COG2197	response regulator
VAB18032_RS13390	COG2345	Transcriptional regulator
VAB18032_RS13415	COG2197	response regulator
VAB18032_RS13420	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
VAB18032_RS13420	COG0825	malonyl-CoA metabolic process
VAB18032_RS13430	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
VAB18032_RS13435	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
VAB18032_RS13450	COG3693	PFAM glycoside hydrolase, family 10
VAB18032_RS13455	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
VAB18032_RS13465	COG1473	amidohydrolase
VAB18032_RS13475	COG1653	transport
VAB18032_RS13480	COG1175	transmembrane transport
VAB18032_RS13485	COG0395	ABC-type sugar transport system, permease component
VAB18032_RS13490	COG3254	rhamnose metabolic process
VAB18032_RS13495	COG4948	Mandelate Racemase Muconate Lactonizing
VAB18032_RS13500	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
VAB18032_RS13510	COG1028	Short-chain dehydrogenase reductase Sdr
VAB18032_RS13550	COG0395	ABC-type sugar transport system, permease component
VAB18032_RS13555	COG4948	Mandelate Racemase Muconate Lactonizing
VAB18032_RS13575	COG1129	ABC transporter
VAB18032_RS13580	COG1172	Belongs to the binding-protein-dependent transport system permease family
VAB18032_RS13585	COG1172	Belongs to the binding-protein-dependent transport system permease family
VAB18032_RS13590	COG4213	ABC transporter substrate-binding protein
VAB18032_RS13605	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
VAB18032_RS13620	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
VAB18032_RS13660	COG2207	Transcriptional regulator
VAB18032_RS13660	COG1609	Transcriptional regulator
VAB18032_RS13725	COG2124	cytochrome p450
VAB18032_RS13730	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
VAB18032_RS13770	COG1404	Belongs to the peptidase S8 family
VAB18032_RS13855	COG0477	Major facilitator Superfamily
VAB18032_RS13875	COG1609	Transcriptional regulator
VAB18032_RS13890	COG1175	transmembrane transport
VAB18032_RS13895	COG0395	ABC-type sugar transport system, permease component
VAB18032_RS13940	COG0697	spore germination
VAB18032_RS13945	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
VAB18032_RS13955	COG1131	(ABC) transporter
VAB18032_RS13970	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
VAB18032_RS13980	COG0018	arginyl-trna synthetase
VAB18032_RS14000	COG0475	glutathione-regulated potassium exporter activity
VAB18032_RS14010	COG1070	Carbohydrate kinase
VAB18032_RS14015	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
VAB18032_RS14050	COG1131	(ABC) transporter
VAB18032_RS14055	COG4585	Histidine kinase
VAB18032_RS14065	COG1960	acyl-CoA dehydrogenase activity
VAB18032_RS14090	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
VAB18032_RS14095	COG1132	(ABC) transporter
VAB18032_RS14110	COG2936	dipeptidyl-peptidase activity
VAB18032_RS14115	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VAB18032_RS14120	COG3629	intracellular signal transduction
VAB18032_RS14120	COG3903	Transcriptional regulator
VAB18032_RS14145	COG0442	prolyl-tRNA aminoacylation
VAB18032_RS14170	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
VAB18032_RS14175	COG3507	Belongs to the glycosyl hydrolase 43 family
VAB18032_RS14200	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
VAB18032_RS14225	COG0640	Transcriptional regulator
VAB18032_RS14265	COG0318	PFAM AMP-dependent synthetase and ligase
VAB18032_RS14270	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
VAB18032_RS14290	COG0640	Transcriptional regulator
VAB18032_RS14295	COG0798	PFAM Bile acid sodium symporter
VAB18032_RS14300	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
VAB18032_RS14335	COG3507	Belongs to the glycosyl hydrolase 43 family
VAB18032_RS14345	COG0747	negative chemotaxis
VAB18032_RS14350	COG0601	transmembrane transport
VAB18032_RS14355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VAB18032_RS14360	COG0444	Belongs to the ABC transporter superfamily
VAB18032_RS14370	COG1228	amidohydrolase
VAB18032_RS14405	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
VAB18032_RS14410	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
VAB18032_RS14450	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
VAB18032_RS14465	COG0346	lactoylglutathione lyase activity
VAB18032_RS14475	COG5398	heme oxygenase
VAB18032_RS14485	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
VAB18032_RS14490	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VAB18032_RS14495	COG4558	Periplasmic binding protein
VAB18032_RS14520	COG0010	Belongs to the arginase family
VAB18032_RS14535	COG0604	alcohol dehydrogenase
VAB18032_RS14535	COG3321	synthase
VAB18032_RS14540	COG0640	Transcriptional regulator
VAB18032_RS14555	COG2124	cytochrome p450
VAB18032_RS14565	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VAB18032_RS14570	COG2814	Major facilitator Superfamily
VAB18032_RS14575	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
VAB18032_RS14595	COG2814	Major facilitator Superfamily
VAB18032_RS14610	COG0747	negative chemotaxis
VAB18032_RS14615	COG0601	transmembrane transport
VAB18032_RS14620	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VAB18032_RS14625	COG0444	Belongs to the ABC transporter superfamily
VAB18032_RS14630	COG4608	Belongs to the ABC transporter superfamily
VAB18032_RS14635	COG1959	2 iron, 2 sulfur cluster binding
VAB18032_RS14645	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
VAB18032_RS14650	COG4208	sulfate ABC transporter
VAB18032_RS14655	COG3842	ATPase activity
VAB18032_RS14675	COG1609	Transcriptional regulator
VAB18032_RS14685	COG1175	transmembrane transport
VAB18032_RS14690	COG0395	ABC-type sugar transport system, permease component
VAB18032_RS14710	COG1129	ABC transporter
VAB18032_RS14715	COG1172	Belongs to the binding-protein-dependent transport system permease family
VAB18032_RS14720	COG4948	Mandelate Racemase Muconate Lactonizing
VAB18032_RS14735	COG1063	alcohol dehydrogenase
VAB18032_RS14740	COG1028	Short-chain dehydrogenase reductase Sdr
VAB18032_RS14770	COG4214	carbohydrate transport
VAB18032_RS14780	COG3345	alpha-galactosidase
VAB18032_RS14800	COG1879	ABC-type sugar transport system periplasmic component
VAB18032_RS14810	COG1172	Belongs to the binding-protein-dependent transport system permease family
VAB18032_RS14815	COG1172	Belongs to the binding-protein-dependent transport system permease family
VAB18032_RS14820	COG2160	L-arabinose isomerase activity
VAB18032_RS14825	COG3507	Belongs to the glycosyl hydrolase 43 family
VAB18032_RS14865	COG0456	acetyltransferase
VAB18032_RS14865	COG1846	Transcriptional regulator
VAB18032_RS14870	COG1960	acyl-CoA dehydrogenase activity
VAB18032_RS14900	COG4221	oxidoreductase activity
VAB18032_RS14905	COG3509	depolymerase
VAB18032_RS14915	COG0179	Fumarylacetoacetate (FAA) hydrolase
VAB18032_RS14955	COG1414	Transcriptional regulator
VAB18032_RS14965	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
VAB18032_RS14970	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
VAB18032_RS14975	COG3485	protocatechuate 3,4-dioxygenase
VAB18032_RS14980	COG3485	protocatechuate 3,4-dioxygenase
VAB18032_RS14985	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
VAB18032_RS14990	COG2267	carboxylic ester hydrolase activity
VAB18032_RS14995	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
VAB18032_RS15000	COG1414	Transcriptional regulator
VAB18032_RS15040	COG0583	DNA-binding transcription factor activity
VAB18032_RS15060	COG0789	Transcriptional regulator
VAB18032_RS15065	COG0667	Aldo Keto reductase
VAB18032_RS15085	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
VAB18032_RS15090	COG0704	Plays a role in the regulation of phosphate uptake
VAB18032_RS15095	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
VAB18032_RS15100	COG0573	inorganic phosphate transmembrane transporter activity
VAB18032_RS15110	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
VAB18032_RS15115	COG0745	RESPONSE REGULATOR receiver
VAB18032_RS15135	COG5001	Diguanylate cyclase
VAB18032_RS15150	COG1609	Transcriptional regulator
VAB18032_RS15160	COG0515	serine threonine protein kinase
VAB18032_RS15160	COG2815	serine threonine protein kinase
VAB18032_RS15170	COG0586	Pfam SNARE associated Golgi protein
VAB18032_RS15185	COG1686	Belongs to the peptidase S11 family
VAB18032_RS15210	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
VAB18032_RS15210	COG2111	Na H antiporter
VAB18032_RS15215	COG1006	Multisubunit Na H antiporter MnhC subunit
VAB18032_RS15220	COG0651	ATP synthesis coupled electron transport
VAB18032_RS15230	COG2212	antiporter activity
VAB18032_RS15240	COG1690	Belongs to the RtcB family
VAB18032_RS15250	COG2197	response regulator
VAB18032_RS15270	COG2197	response regulator
VAB18032_RS15275	COG4585	Histidine kinase
VAB18032_RS15285	COG1131	(ABC) transporter
VAB18032_RS15305	COG1132	(ABC) transporter
VAB18032_RS15310	COG1132	(ABC) transporter
VAB18032_RS15340	COG1136	(ABC) transporter
VAB18032_RS15360	COG5002	protein histidine kinase activity
VAB18032_RS15365	COG0745	RESPONSE REGULATOR receiver
VAB18032_RS15405	COG0438	transferase activity, transferring glycosyl groups
VAB18032_RS15420	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
VAB18032_RS15425	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
VAB18032_RS15425	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
VAB18032_RS15460	COG1120	ATPase activity
VAB18032_RS15465	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VAB18032_RS15470	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VAB18032_RS15485	COG3486	L-lysine 6-monooxygenase (NADPH) activity
VAB18032_RS15525	COG2226	methyltransferase
VAB18032_RS15530	COG0673	inositol 2-dehydrogenase activity
VAB18032_RS15545	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VAB18032_RS15565	COG1960	acyl-CoA dehydrogenase activity
VAB18032_RS15595	COG1509	lysine 2,3-aminomutase activity
VAB18032_RS15600	COG0604	alcohol dehydrogenase
VAB18032_RS15605	COG1228	amidohydrolase
VAB18032_RS15610	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
VAB18032_RS15615	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
VAB18032_RS15620	COG1607	acyl-coa hydrolase
VAB18032_RS15635	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
VAB18032_RS15645	COG1216	Glycosyl transferase, family 2
VAB18032_RS15665	COG1609	Transcriptional regulator
VAB18032_RS15670	COG1472	Belongs to the glycosyl hydrolase 3 family
VAB18032_RS15675	COG1940	carbohydrate kinase activity
VAB18032_RS15685	COG1280	lysine exporter protein (LysE YggA)
VAB18032_RS15750	COG0071	Belongs to the small heat shock protein (HSP20) family
VAB18032_RS15755	COG4974	Belongs to the 'phage' integrase family
VAB18032_RS15765	COG1136	(ABC) transporter
VAB18032_RS15770	COG1136	(ABC) transporter
VAB18032_RS15785	COG1435	thymidine kinase activity
VAB18032_RS15790	COG2270	Major facilitator Superfamily
VAB18032_RS15800	COG4989	oxidoreductase activity
VAB18032_RS15805	COG0204	Acyl-transferase
VAB18032_RS15810	COG1271	oxidase subunit
VAB18032_RS15815	COG1294	oxidase, subunit
VAB18032_RS15835	COG1028	Short-chain dehydrogenase reductase Sdr
VAB18032_RS15855	COG1335	isochorismatase
VAB18032_RS15865	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
VAB18032_RS15880	COG1012	belongs to the aldehyde dehydrogenase family
VAB18032_RS15890	COG1804	L-carnitine dehydratase bile acid-inducible protein F
VAB18032_RS15905	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
VAB18032_RS15925	COG2267	carboxylic ester hydrolase activity
VAB18032_RS15940	COG1802	Transcriptional regulator
VAB18032_RS15990	COG0242	peptide deformylase activity
VAB18032_RS16005	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
VAB18032_RS16005	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
VAB18032_RS16010	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
VAB18032_RS16020	COG1017	nitric oxide dioxygenase activity
VAB18032_RS16020	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
VAB18032_RS16125	COG1921	L-seryl-tRNASec selenium transferase activity
VAB18032_RS16135	COG0437	4 iron, 4 sulfur cluster binding
VAB18032_RS16140	COG0243	molybdopterin cofactor binding
VAB18032_RS16140	COG3383	formate dehydrogenase (NAD+) activity
VAB18032_RS16145	COG3383	formate dehydrogenase (NAD+) activity
VAB18032_RS16145	COG0243	molybdopterin cofactor binding
VAB18032_RS16165	COG1028	Short-chain dehydrogenase reductase Sdr
VAB18032_RS16170	COG0644	oxidoreductase
VAB18032_RS16195	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
VAB18032_RS16230	COG3384	dioxygenase
VAB18032_RS16235	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
VAB18032_RS16245	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
VAB18032_RS16265	COG1357	PFAM Pentapeptide repeats (8 copies)
VAB18032_RS16270	COG0328	RNA-DNA hybrid ribonuclease activity
VAB18032_RS16300	COG3012	SEC-C Motif Domain Protein
VAB18032_RS16325	COG0069	glutamate synthase activity
VAB18032_RS16330	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
VAB18032_RS16395	COG1131	(ABC) transporter
VAB18032_RS16410	COG3265	gluconokinase activity
VAB18032_RS16415	COG4948	Mandelate Racemase Muconate Lactonizing
VAB18032_RS16425	COG0800	Aldolase
VAB18032_RS16430	COG4948	Mandelate Racemase Muconate Lactonizing
VAB18032_RS16435	COG0395	ABC-type sugar transport system, permease component
VAB18032_RS16440	COG1175	transmembrane transport
VAB18032_RS16450	COG1802	Transcriptional regulator
VAB18032_RS16470	COG1595	DNA-templated transcription, initiation
VAB18032_RS16475	COG0702	epimerase
VAB18032_RS16540	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
VAB18032_RS16595	COG2197	response regulator
VAB18032_RS16655	COG2814	Major facilitator Superfamily
VAB18032_RS16660	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
VAB18032_RS16685	COG0789	Transcriptional regulator
VAB18032_RS16695	COG2815	serine threonine protein kinase
VAB18032_RS16695	COG0515	serine threonine protein kinase
VAB18032_RS16755	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
VAB18032_RS16760	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VAB18032_RS16760	COG0515	serine threonine protein kinase
VAB18032_RS16775	COG0328	RNA-DNA hybrid ribonuclease activity
VAB18032_RS16795	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
VAB18032_RS16805	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VAB18032_RS16810	COG1846	Transcriptional regulator
VAB18032_RS16830	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
VAB18032_RS16835	COG1063	alcohol dehydrogenase
VAB18032_RS16850	COG1175	transmembrane transport
VAB18032_RS16885	COG1132	(ABC) transporter
VAB18032_RS16885	COG2375	cellular response to nickel ion
VAB18032_RS16905	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
VAB18032_RS16985	COG2318	DinB family
VAB18032_RS17030	COG4106	trans-aconitate 2-methyltransferase activity
VAB18032_RS17045	COG3483	tryptophan 2,3-dioxygenase activity
VAB18032_RS17055	COG0714	Associated with various cellular activities
VAB18032_RS17080	COG0789	Transcriptional regulator
VAB18032_RS17105	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
VAB18032_RS17115	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
VAB18032_RS17195	COG1725	Transcriptional regulator
VAB18032_RS17210	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
VAB18032_RS17250	COG2207	Transcriptional regulator
VAB18032_RS17265	COG1132	(ABC) transporter
VAB18032_RS17280	COG1733	regulation of RNA biosynthetic process
VAB18032_RS17295	COG2855	membrane
VAB18032_RS17305	COG3903	Transcriptional regulator
VAB18032_RS17305	COG3629	intracellular signal transduction
VAB18032_RS17335	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
VAB18032_RS17345	COG3251	PFAM MbtH domain protein
VAB18032_RS17365	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
VAB18032_RS17375	COG1181	Belongs to the D-alanine--D-alanine ligase family
VAB18032_RS17400	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
VAB18032_RS17410	COG0165	Argininosuccinate lyase
VAB18032_RS17440	COG0300	oxidoreductase activity
VAB18032_RS17440	COG1028	Short-chain dehydrogenase reductase Sdr
VAB18032_RS17440	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
VAB18032_RS17440	COG0318	PFAM AMP-dependent synthetase and ligase
VAB18032_RS17440	COG3321	synthase
VAB18032_RS17475	COG0028	Belongs to the TPP enzyme family
VAB18032_RS17480	COG0277	FAD linked oxidase domain protein
VAB18032_RS17485	COG0436	Aminotransferase
VAB18032_RS17495	COG1028	Short-chain dehydrogenase reductase Sdr
VAB18032_RS17520	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
VAB18032_RS17525	COG0475	glutathione-regulated potassium exporter activity
VAB18032_RS17555	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
VAB18032_RS17555	COG2508	Transcriptional regulator
VAB18032_RS17570	COG3842	ATPase activity
VAB18032_RS17590	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
VAB18032_RS17635	COG0326	Molecular chaperone. Has ATPase activity
VAB18032_RS17650	COG5002	protein histidine kinase activity
VAB18032_RS17655	COG0745	RESPONSE REGULATOR receiver
VAB18032_RS17720	COG0683	leucine binding
VAB18032_RS17735	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
VAB18032_RS17745	COG0829	nickel cation binding
VAB18032_RS17750	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
VAB18032_RS17755	COG0830	nickel cation binding
VAB18032_RS17765	COG0832	Belongs to the urease beta subunit family
VAB18032_RS17770	COG0831	urea catabolic process
VAB18032_RS17780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VAB18032_RS17785	COG0765	amino acid transport
VAB18032_RS17790	COG1126	abc transporter atp-binding protein
VAB18032_RS17805	COG3559	Exporter of polyketide antibiotics
VAB18032_RS17810	COG1131	(ABC) transporter
VAB18032_RS17815	COG1309	transcriptional regulator
VAB18032_RS17825	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
VAB18032_RS17855	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
VAB18032_RS17860	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
VAB18032_RS17865	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
VAB18032_RS17870	COG1116	anion transmembrane transporter activity
VAB18032_RS17875	COG2855	membrane
VAB18032_RS17885	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
VAB18032_RS17925	COG0515	serine threonine protein kinase
VAB18032_RS17935	COG1132	(ABC) transporter
VAB18032_RS17940	COG1132	(ABC) transporter
VAB18032_RS17945	COG2197	response regulator
VAB18032_RS17950	COG2197	response regulator
VAB18032_RS17955	COG0805	protein transport
VAB18032_RS17960	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
VAB18032_RS17970	COG2378	regulation of single-species biofilm formation
VAB18032_RS17990	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
VAB18032_RS18035	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
VAB18032_RS18040	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
VAB18032_RS18055	COG4122	O-methyltransferase activity
VAB18032_RS18065	COG1222	aaa ATPase
VAB18032_RS18085	COG0517	IMP dehydrogenase activity
VAB18032_RS18085	COG1994	Peptidase M50
VAB18032_RS18095	COG4585	Histidine kinase
VAB18032_RS18100	COG2197	response regulator
VAB18032_RS18105	COG1136	(ABC) transporter
VAB18032_RS18105	COG0577	efflux transmembrane transporter activity
VAB18032_RS18110	COG1136	(ABC) transporter
VAB18032_RS18110	COG0577	efflux transmembrane transporter activity
VAB18032_RS18115	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VAB18032_RS18125	COG0387	Pfam Sodium calcium exchanger
VAB18032_RS18140	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
VAB18032_RS18145	COG0646	methionine synthase
VAB18032_RS18145	COG1410	methionine synthase
VAB18032_RS18160	COG0215	cysteine-tRNA ligase activity
VAB18032_RS18185	COG1968	undecaprenyl-diphosphatase activity
VAB18032_RS18190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
VAB18032_RS18195	COG0667	Aldo Keto reductase
VAB18032_RS18215	COG2140	Oxalate decarboxylase
VAB18032_RS18235	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
VAB18032_RS18260	COG0542	response to heat
VAB18032_RS18280	COG1674	ftsk spoiiie
VAB18032_RS18305	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
VAB18032_RS18320	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
VAB18032_RS18330	COG0745	RESPONSE REGULATOR receiver
VAB18032_RS18335	COG0745	RESPONSE REGULATOR receiver
VAB18032_RS18370	COG0653	protein targeting
VAB18032_RS18375	COG0463	Glycosyl transferase, family 2
VAB18032_RS18385	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
VAB18032_RS18400	COG0028	Belongs to the TPP enzyme family
VAB18032_RS18415	COG2409	Drug exporters of the RND superfamily
VAB18032_RS18430	COG2367	Beta-lactamase
VAB18032_RS18465	COG1476	TRANSCRIPTIONal
VAB18032_RS18475	COG0137	argininosuccinate synthase activity
VAB18032_RS18535	COG0745	RESPONSE REGULATOR receiver
VAB18032_RS18575	COG2205	protein histidine kinase activity
VAB18032_RS18580	COG0745	RESPONSE REGULATOR receiver
VAB18032_RS18590	COG0515	serine threonine protein kinase
VAB18032_RS18590	COG2815	serine threonine protein kinase
VAB18032_RS18605	COG0784	Response regulator, receiver
VAB18032_RS18625	COG1366	Belongs to the anti-sigma-factor antagonist family
VAB18032_RS18630	COG1366	Belongs to the anti-sigma-factor antagonist family
VAB18032_RS18645	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
VAB18032_RS18655	COG0543	2 iron, 2 sulfur cluster binding
VAB18032_RS18655	COG0633	Ferredoxin
VAB18032_RS18660	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
VAB18032_RS18670	COG1804	L-carnitine dehydratase bile acid-inducible protein F
VAB18032_RS18720	COG0489	protein tyrosine kinase activity
VAB18032_RS18725	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
VAB18032_RS18735	COG2119	membrane
VAB18032_RS18740	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
VAB18032_RS18745	COG0121	glutamine amidotransferase
VAB18032_RS18750	COG1262	PFAM Formylglycine-generating sulfatase enzyme
VAB18032_RS18770	COG0515	serine threonine protein kinase
VAB18032_RS18785	COG1136	(ABC) transporter
VAB18032_RS18785	COG0577	efflux transmembrane transporter activity
VAB18032_RS18790	COG2197	response regulator
VAB18032_RS18795	COG4585	Histidine kinase
VAB18032_RS18825	COG0367	asparagine synthase
VAB18032_RS18840	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
VAB18032_RS18875	COG1376	ErfK ybiS ycfS ynhG family protein
VAB18032_RS18915	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
VAB18032_RS18925	COG3973	AAA domain
VAB18032_RS18960	COG3903	Transcriptional regulator
VAB18032_RS18960	COG3629	intracellular signal transduction
VAB18032_RS19010	COG1672	PFAM Archaeal ATPase
VAB18032_RS19010	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
VAB18032_RS19015	COG2226	methyltransferase
VAB18032_RS19020	COG0738	Major facilitator superfamily
VAB18032_RS19115	COG0706	membrane insertase activity
VAB18032_RS19120	COG1472	Belongs to the glycosyl hydrolase 3 family
VAB18032_RS19125	COG0395	ABC-type sugar transport system, permease component
VAB18032_RS19130	COG1175	transmembrane transport
VAB18032_RS19140	COG1609	Transcriptional regulator
VAB18032_RS19180	COG0395	ABC-type sugar transport system, permease component
VAB18032_RS19185	COG1175	transmembrane transport
VAB18032_RS19200	COG0673	inositol 2-dehydrogenase activity
VAB18032_RS19205	COG1904	glucuronate isomerase
VAB18032_RS19210	COG4948	Mandelate Racemase Muconate Lactonizing
VAB18032_RS19215	COG0246	Mannitol dehydrogenase
VAB18032_RS19225	COG3866	Pectate lyase
VAB18032_RS19240	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
VAB18032_RS19265	COG4608	Belongs to the ABC transporter superfamily
VAB18032_RS19275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VAB18032_RS19280	COG0601	transmembrane transport
VAB18032_RS19290	COG4326	sporulation control protein
VAB18032_RS19295	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
VAB18032_RS19320	COG3509	depolymerase
VAB18032_RS19345	COG3458	cephalosporin-C deacetylase activity
VAB18032_RS19355	COG4209	transmembrane transport
VAB18032_RS19360	COG0395	ABC-type sugar transport system, permease component
VAB18032_RS19365	COG1653	transport
VAB18032_RS19455	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
VAB18032_RS19470	COG4585	Histidine kinase
VAB18032_RS19495	COG3507	Belongs to the glycosyl hydrolase 43 family
VAB18032_RS19500	COG3507	Belongs to the glycosyl hydrolase 43 family
VAB18032_RS19525	COG1704	LemA family
VAB18032_RS19550	COG0009	L-threonylcarbamoyladenylate synthase
VAB18032_RS19555	COG4260	virion core protein, lumpy skin disease virus
VAB18032_RS19600	COG1132	(ABC) transporter
VAB18032_RS19615	COG2353	YceI-like domain
VAB18032_RS19620	COG1414	Transcriptional regulator
VAB18032_RS19625	COG0800	Aldolase
VAB18032_RS19630	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VAB18032_RS19650	COG0604	alcohol dehydrogenase
VAB18032_RS19650	COG3321	synthase
VAB18032_RS19655	COG2207	Transcriptional regulator
VAB18032_RS19675	COG0778	Nitroreductase
VAB18032_RS19680	COG0492	ferredoxin-NADP+ reductase activity
VAB18032_RS19700	COG0513	Belongs to the DEAD box helicase family
VAB18032_RS19720	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
VAB18032_RS19720	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VAB18032_RS19725	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
VAB18032_RS19725	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
VAB18032_RS19775	COG4585	Histidine kinase
VAB18032_RS19785	COG1136	(ABC) transporter
VAB18032_RS19785	COG0577	efflux transmembrane transporter activity
VAB18032_RS19790	COG0577	efflux transmembrane transporter activity
VAB18032_RS19800	COG1063	alcohol dehydrogenase
VAB18032_RS19805	COG0596	Alpha beta hydrolase
VAB18032_RS19820	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
VAB18032_RS19865	COG0596	Alpha beta hydrolase
VAB18032_RS19890	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
VAB18032_RS19900	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
VAB18032_RS19910	COG2267	carboxylic ester hydrolase activity
VAB18032_RS19930	COG0596	Alpha beta hydrolase
VAB18032_RS19950	COG0657	acetylesterase activity
VAB18032_RS19965	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
VAB18032_RS19965	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
VAB18032_RS19970	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
VAB18032_RS20015	COG1917	Cupin 2, conserved barrel domain protein
VAB18032_RS20015	COG4977	sequence-specific DNA binding
VAB18032_RS20030	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
VAB18032_RS20040	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
VAB18032_RS20045	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
VAB18032_RS20070	COG3251	PFAM MbtH domain protein
VAB18032_RS20075	COG0017	Asparaginyl-tRNA synthetase
VAB18032_RS20080	COG0069	glutamate synthase activity
VAB18032_RS20085	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
VAB18032_RS20135	COG3629	intracellular signal transduction
VAB18032_RS20135	COG3903	Transcriptional regulator
VAB18032_RS20195	COG0714	Associated with various cellular activities
VAB18032_RS20230	COG4733	cellulase activity
VAB18032_RS20230	COG5297	Belongs to the glycosyl hydrolase family 6
VAB18032_RS20235	COG2723	6-phospho-beta-galactosidase activity
VAB18032_RS20260	COG2018	Roadblock/LC7 domain
VAB18032_RS20280	COG0655	NAD(P)H dehydrogenase (quinone) activity
VAB18032_RS20290	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VAB18032_RS20300	COG0697	spore germination
VAB18032_RS20305	COG1620	l-lactate permease
VAB18032_RS20375	COG2936	dipeptidyl-peptidase activity
VAB18032_RS20440	COG2226	methyltransferase
VAB18032_RS20445	COG0494	nUDIX hydrolase
VAB18032_RS20455	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
VAB18032_RS20465	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
VAB18032_RS20495	COG1988	membrane-bound metal-dependent
VAB18032_RS20500	COG1609	Transcriptional regulator
VAB18032_RS20505	COG1501	Belongs to the glycosyl hydrolase 31 family
VAB18032_RS20565	COG0395	ABC-type sugar transport system, permease component
VAB18032_RS20570	COG1175	transmembrane transport
VAB18032_RS20580	COG4821	SIS domain
VAB18032_RS20605	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
VAB18032_RS20625	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
VAB18032_RS20630	COG1365	unkown
VAB18032_RS20640	COG1733	regulation of RNA biosynthetic process
VAB18032_RS20655	COG4733	cellulase activity
VAB18032_RS20655	COG5297	Belongs to the glycosyl hydrolase family 6
VAB18032_RS20660	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
VAB18032_RS20665	COG0583	DNA-binding transcription factor activity
VAB18032_RS20685	COG1252	NADH dehydrogenase
VAB18032_RS20690	COG1595	DNA-templated transcription, initiation
VAB18032_RS20705	COG0028	Belongs to the TPP enzyme family
VAB18032_RS20755	COG1028	Short-chain dehydrogenase reductase Sdr
VAB18032_RS20770	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
VAB18032_RS20775	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
VAB18032_RS20795	COG0714	Associated with various cellular activities
VAB18032_RS20835	COG0006	proline dipeptidase activity
VAB18032_RS20895	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
VAB18032_RS20910	COG2018	Roadblock/LC7 domain
VAB18032_RS20950	COG1309	transcriptional regulator
VAB18032_RS20960	COG3220	belongs to the UPF0276 family
VAB18032_RS20970	COG1028	Short-chain dehydrogenase reductase Sdr
VAB18032_RS20975	COG3663	DNA glycosylase
VAB18032_RS20980	COG1132	(ABC) transporter
VAB18032_RS20995	COG0488	(ABC) transporter
VAB18032_RS21000	COG2321	neutral zinc metallopeptidase
VAB18032_RS21030	COG0822	iron-sulfur transferase activity
VAB18032_RS21035	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
VAB18032_RS21040	COG0396	ATPase activity
VAB18032_RS21045	COG2146	nitrite reductase [NAD(P)H] activity
VAB18032_RS21080	COG0109	protoheme IX farnesyltransferase activity
VAB18032_RS21090	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
VAB18032_RS21095	COG0166	Belongs to the GPI family
VAB18032_RS21110	COG0363	glucosamine-6-phosphate deaminase activity
VAB18032_RS21120	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
VAB18032_RS21125	COG0149	triose-phosphate isomerase activity
VAB18032_RS21130	COG0126	phosphoglycerate kinase activity
VAB18032_RS21135	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VAB18032_RS21140	COG1481	regulation of sporulation
VAB18032_RS21150	COG1660	Displays ATPase and GTPase activities
VAB18032_RS21180	COG0702	epimerase
VAB18032_RS21190	COG0322	excinuclease ABC activity
VAB18032_RS21210	COG1162	GTPase activity
VAB18032_RS21230	COG1278	Cold shock
VAB18032_RS21245	COG1846	Transcriptional regulator
VAB18032_RS21250	COG2409	Drug exporters of the RND superfamily
VAB18032_RS21255	COG0741	lytic transglycosylase activity
VAB18032_RS21260	COG0586	Pfam SNARE associated Golgi protein
VAB18032_RS21265	COG1217	gtp-binding protein TYPA
VAB18032_RS21280	COG2329	Antibiotic biosynthesis monooxygenase
VAB18032_RS21300	COG0237	dephospho-CoA kinase activity
VAB18032_RS21300	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
VAB18032_RS21305	COG0539	negative regulation of cytoplasmic translation
VAB18032_RS21330	COG0789	Transcriptional regulator
VAB18032_RS21340	COG1126	abc transporter atp-binding protein
VAB18032_RS21345	COG0765	amino acid transport
VAB18032_RS21350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VAB18032_RS21400	COG0626	cystathionine gamma-synthase activity
VAB18032_RS21410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
VAB18032_RS21415	COG3401	FG-GAP repeat protein
VAB18032_RS21425	COG0730	response to heat
VAB18032_RS21435	COG1946	Acyl-CoA thioesterase
VAB18032_RS21450	COG0667	Aldo Keto reductase
VAB18032_RS21460	COG0861	Integral membrane protein TerC family
VAB18032_RS21465	COG1028	Short-chain dehydrogenase reductase Sdr
VAB18032_RS21540	COG2755	lipolytic protein G-D-S-L family
VAB18032_RS21550	COG0067	glutamate synthase
VAB18032_RS21550	COG0069	glutamate synthase activity
VAB18032_RS21550	COG0070	glutamate synthase
VAB18032_RS21565	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
VAB18032_RS21570	COG0159	tryptophan synthase activity
VAB18032_RS21575	COG0133	tryptophan synthase activity
VAB18032_RS21595	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
VAB18032_RS21605	COG1131	(ABC) transporter
VAB18032_RS21620	COG1132	(ABC) transporter
VAB18032_RS21625	COG1132	(ABC) transporter
VAB18032_RS21635	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
VAB18032_RS21640	COG1022	Amp-dependent synthetase and ligase
VAB18032_RS21650	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
VAB18032_RS21665	COG0107	imidazoleglycerol-phosphate synthase activity
VAB18032_RS21670	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
VAB18032_RS21680	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
VAB18032_RS21685	COG0131	Imidazoleglycerol-phosphate dehydratase
VAB18032_RS21690	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
VAB18032_RS21695	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
VAB18032_RS21700	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
VAB18032_RS21725	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
VAB18032_RS21730	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
VAB18032_RS21745	COG3599	regulation of cell shape
VAB18032_RS21755	COG1799	cell septum assembly
VAB18032_RS21765	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
VAB18032_RS21770	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
VAB18032_RS21775	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
VAB18032_RS21780	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
VAB18032_RS21790	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
VAB18032_RS21800	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
VAB18032_RS21805	COG0768	penicillin binding
VAB18032_RS21815	COG0275	rRNA processing
VAB18032_RS21820	COG2001	Belongs to the MraZ family
VAB18032_RS21830	COG3442	glutamine amidotransferase
VAB18032_RS21850	COG0495	leucyl-tRNA aminoacylation
VAB18032_RS21855	COG0714	Associated with various cellular activities
VAB18032_RS21875	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
VAB18032_RS21885	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
VAB18032_RS21890	COG0587	DNA-directed DNA polymerase activity
VAB18032_RS21950	COG0142	geranyltranstransferase activity
VAB18032_RS21960	COG0515	serine threonine protein kinase
VAB18032_RS21960	COG2815	serine threonine protein kinase
VAB18032_RS21965	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
VAB18032_RS21975	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
VAB18032_RS21990	COG0386	Belongs to the glutathione peroxidase family
VAB18032_RS22065	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
VAB18032_RS22075	COG2072	flavoprotein involved in K transport
VAB18032_RS22085	COG1940	carbohydrate kinase activity
VAB18032_RS22110	COG2197	response regulator
VAB18032_RS22140	COG0438	transferase activity, transferring glycosyl groups
VAB18032_RS22145	COG0501	Belongs to the peptidase M48B family
VAB18032_RS22160	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
VAB18032_RS22170	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
VAB18032_RS22185	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
VAB18032_RS22195	COG2010	Cytochrome c
VAB18032_RS22215	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
VAB18032_RS22230	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
VAB18032_RS22245	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VAB18032_RS22260	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
VAB18032_RS22265	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
VAB18032_RS22280	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
VAB18032_RS22285	COG1396	sequence-specific DNA binding
VAB18032_RS22310	COG0667	Aldo Keto reductase
VAB18032_RS22315	COG1994	Peptidase M50
VAB18032_RS22330	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
VAB18032_RS22335	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
VAB18032_RS22345	COG0404	The glycine cleavage system catalyzes the degradation of glycine
VAB18032_RS22350	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
VAB18032_RS22360	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VAB18032_RS22365	COG0508	dehydrogenase complex catalyzes the overall conversion of
VAB18032_RS22400	COG0321	lipoyl(octanoyl) transferase activity
VAB18032_RS22405	COG0017	Asparaginyl-tRNA synthetase
VAB18032_RS22410	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
VAB18032_RS22465	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
VAB18032_RS22470	COG0519	Catalyzes the synthesis of GMP from XMP
VAB18032_RS22470	COG0518	GMP synthase (glutamine-hydrolyzing) activity
VAB18032_RS22475	COG1619	proteins homologs of microcin C7 resistance protein MccF
VAB18032_RS22485	COG3766	membrane
VAB18032_RS22490	COG0174	glutamine synthetase
VAB18032_RS22495	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
VAB18032_RS22495	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
VAB18032_RS22500	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
VAB18032_RS22515	COG0557	exoribonuclease II activity
VAB18032_RS22525	COG1051	belongs to the nudix hydrolase family
VAB18032_RS22535	COG3708	Transcriptional regulator
VAB18032_RS22535	COG2207	Transcriptional regulator
VAB18032_RS22575	COG0730	response to heat
VAB18032_RS22590	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
VAB18032_RS22620	COG4279	zinc finger
VAB18032_RS22625	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
VAB18032_RS22635	COG2318	DinB family
VAB18032_RS22700	COG0022	dehydrogenase e1 component
VAB18032_RS22705	COG0432	Pfam Uncharacterised protein family UPF0047
VAB18032_RS22710	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
VAB18032_RS22735	COG2814	Major facilitator Superfamily
VAB18032_RS22740	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
VAB18032_RS22765	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
VAB18032_RS22770	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
VAB18032_RS22775	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
VAB18032_RS22800	COG2267	carboxylic ester hydrolase activity
VAB18032_RS22805	COG3973	AAA domain
VAB18032_RS22815	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
VAB18032_RS22815	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
VAB18032_RS22840	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
VAB18032_RS22840	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
VAB18032_RS22855	COG3268	Saccharopine dehydrogenase
VAB18032_RS22860	COG0789	Transcriptional regulator
VAB18032_RS22860	COG4978	Transcriptional regulator
VAB18032_RS22865	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
VAB18032_RS22910	COG0277	FAD linked oxidase domain protein
VAB18032_RS22935	COG1131	(ABC) transporter
VAB18032_RS22960	COG4941	Belongs to the sigma-70 factor family
VAB18032_RS22985	COG0789	Transcriptional regulator
VAB18032_RS23035	COG1940	carbohydrate kinase activity
VAB18032_RS23055	COG0142	geranyltranstransferase activity
VAB18032_RS23095	COG0673	inositol 2-dehydrogenase activity
VAB18032_RS23105	COG1172	Belongs to the binding-protein-dependent transport system permease family
VAB18032_RS23110	COG1129	ABC transporter
VAB18032_RS23140	COG0232	Belongs to the dGTPase family. Type 2 subfamily
VAB18032_RS23155	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
VAB18032_RS23155	COG0574	Belongs to the PEP-utilizing enzyme family
VAB18032_RS23190	COG0423	glycine-tRNA ligase activity
VAB18032_RS23210	COG0803	Belongs to the bacterial solute-binding protein 9 family
VAB18032_RS23210	COG3443	Belongs to the bacterial solute-binding protein 9 family
VAB18032_RS23215	COG1121	(ABC) transporter
VAB18032_RS23220	COG1108	ABC-type Mn2 Zn2 transport systems permease components
VAB18032_RS23245	COG4821	SIS domain
VAB18032_RS23250	COG0596	Alpha beta hydrolase
VAB18032_RS23260	COG0701	Predicted permease
VAB18032_RS23265	COG4721	ABC-type cobalt transport system, permease component
VAB18032_RS23270	COG4172	Belongs to the ABC transporter superfamily
VAB18032_RS23275	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
VAB18032_RS23280	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
VAB18032_RS23290	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
VAB18032_RS23295	COG1381	Involved in DNA repair and RecF pathway recombination
VAB18032_RS23310	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
VAB18032_RS23325	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
VAB18032_RS23340	COG0537	adenosine 5'-monophosphoramidase activity
VAB18032_RS23345	COG1028	Short-chain dehydrogenase reductase Sdr
VAB18032_RS23355	COG0484	heat shock protein binding
VAB18032_RS23360	COG1420	regulation of RNA biosynthetic process
VAB18032_RS23375	COG1024	Enoyl-CoA hydratase
VAB18032_RS23395	COG0481	GTPase activity
VAB18032_RS23410	COG0268	Binds directly to 16S ribosomal RNA
VAB18032_RS23425	COG2333	competence protein COMEC
VAB18032_RS23425	COG0658	competence protein
VAB18032_RS23440	COG1307	EDD domain protein, DegV family
VAB18032_RS23445	COG0406	alpha-ribazole phosphatase activity
VAB18032_RS23450	COG0799	negative regulation of ribosome biogenesis
VAB18032_RS23455	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
VAB18032_RS23490	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
VAB18032_RS23495	COG0211	Belongs to the bacterial ribosomal protein bL27 family
VAB18032_RS23500	COG0261	This protein binds to 23S rRNA in the presence of protein L20
VAB18032_RS23505	COG1530	ribonuclease E activity
VAB18032_RS23525	COG3046	protein related to deoxyribodipyrimidine photolyase
VAB18032_RS23530	COG0204	Acyl-transferase
VAB18032_RS23535	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
VAB18032_RS23540	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
VAB18032_RS23545	COG1595	DNA-templated transcription, initiation
VAB18032_RS23550	COG0105	UTP biosynthetic process
VAB18032_RS23565	COG0285	dihydrofolate synthase activity
VAB18032_RS23570	COG0525	valine-tRNA ligase activity
VAB18032_RS23605	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
VAB18032_RS23610	COG0740	serine-type endopeptidase activity
VAB18032_RS23615	COG0740	serine-type endopeptidase activity
VAB18032_RS23620	COG0544	peptidyl-prolyl cis-trans isomerase activity
VAB18032_RS23655	COG1132	(ABC) transporter
VAB18032_RS23685	COG4552	Acetyltransferase involved in intracellular survival and related
VAB18032_RS23695	COG0698	ribose 5-phosphate isomerase
VAB18032_RS23705	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
VAB18032_RS23715	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
VAB18032_RS23735	COG4101	3-hydroxyanthranilate 3,4-dioxygenase activity
VAB18032_RS23750	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
VAB18032_RS23755	COG4569	acetaldehyde dehydrogenase (acetylating) activity
VAB18032_RS23770	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VAB18032_RS23775	COG3844	kynureninase activity
VAB18032_RS23780	COG3483	tryptophan 2,3-dioxygenase activity
VAB18032_RS23785	COG1522	sequence-specific DNA binding
VAB18032_RS23805	COG0668	transmembrane transport
VAB18032_RS23840	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
VAB18032_RS23845	COG0561	phosphatase activity
VAB18032_RS23845	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VAB18032_RS23855	COG1648	precorrin-2 dehydrogenase activity
VAB18032_RS23855	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
VAB18032_RS23860	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
VAB18032_RS23875	COG1797	cobyrinic acid a,c-diamide synthase activity
VAB18032_RS23885	COG1793	dna ligase
VAB18032_RS23910	COG1492	cobalamin metabolic process
VAB18032_RS23915	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
VAB18032_RS23920	COG0629	single-stranded DNA binding
VAB18032_RS23990	COG1674	ftsk spoiiie
VAB18032_RS24020	COG0596	Alpha beta hydrolase
VAB18032_RS24035	COG3795	YCII-related domain
VAB18032_RS24040	COG4941	Belongs to the sigma-70 factor family
VAB18032_RS24055	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VAB18032_RS24065	COG0596	Alpha beta hydrolase
VAB18032_RS24075	COG1216	Glycosyl transferase, family 2
VAB18032_RS24085	COG1132	(ABC) transporter
VAB18032_RS24090	COG1216	Glycosyl transferase, family 2
VAB18032_RS24110	COG2197	response regulator
VAB18032_RS24165	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VAB18032_RS24195	COG1566	PFAM secretion protein HlyD family protein
VAB18032_RS24210	COG0791	NLP P60 protein
VAB18032_RS24220	COG1737	Transcriptional regulator
VAB18032_RS24225	COG1028	Short-chain dehydrogenase reductase Sdr
VAB18032_RS24230	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
VAB18032_RS24250	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
VAB18032_RS24255	COG4991	sh3 domain protein
VAB18032_RS24260	COG1653	transport
VAB18032_RS24265	COG1175	transmembrane transport
VAB18032_RS24270	COG0395	ABC-type sugar transport system, permease component
VAB18032_RS24275	COG1609	Transcriptional regulator
VAB18032_RS24280	COG0366	Alpha amylase catalytic
VAB18032_RS24290	COG1070	Carbohydrate kinase
VAB18032_RS24295	COG2115	Belongs to the xylose isomerase family
VAB18032_RS24305	COG2208	phosphoserine phosphatase activity
VAB18032_RS24305	COG2770	Histidine kinase
VAB18032_RS24330	COG2706	6-phosphogluconolactonase activity
VAB18032_RS24370	COG5297	Belongs to the glycosyl hydrolase family 6
VAB18032_RS24385	COG3547	Transposase (IS116 IS110 IS902 family)
VAB18032_RS24390	COG2902	Dehydrogenase
VAB18032_RS24400	COG0010	Belongs to the arginase family
VAB18032_RS24405	COG3118	belongs to the thioredoxin family
VAB18032_RS24410	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
VAB18032_RS24410	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
VAB18032_RS24425	COG0183	Belongs to the thiolase family
VAB18032_RS24430	COG0346	lactoylglutathione lyase activity
VAB18032_RS24475	COG1250	3-hydroxyacyl-CoA dehydrogenase
VAB18032_RS24495	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
VAB18032_RS24505	COG0726	polysaccharide deacetylase
VAB18032_RS24515	COG1131	(ABC) transporter
VAB18032_RS24525	COG1250	3-hydroxyacyl-CoA dehydrogenase
VAB18032_RS24570	COG0355	proton-transporting ATP synthase activity, rotational mechanism
VAB18032_RS24580	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
VAB18032_RS24585	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
VAB18032_RS24590	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
VAB18032_RS24595	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
VAB18032_RS24600	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
VAB18032_RS24605	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
VAB18032_RS24610	COG0356	it plays a direct role in the translocation of protons across the membrane
VAB18032_RS24625	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
VAB18032_RS24630	COG0702	epimerase
VAB18032_RS24635	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
VAB18032_RS24640	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
VAB18032_RS24650	COG2890	protein-(glutamine-N5) methyltransferase activity
VAB18032_RS24660	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
VAB18032_RS24665	COG0254	rRNA binding
VAB18032_RS24675	COG0083	homoserine kinase activity
VAB18032_RS24680	COG2814	Major facilitator Superfamily
VAB18032_RS24685	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VAB18032_RS24695	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
VAB18032_RS24705	COG0019	diaminopimelate decarboxylase activity
VAB18032_RS24710	COG0018	arginyl-trna synthetase
VAB18032_RS24735	COG1595	DNA-templated transcription, initiation
VAB18032_RS24745	COG0515	serine threonine protein kinase
VAB18032_RS24745	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VAB18032_RS24775	COG2409	Drug exporters of the RND superfamily
VAB18032_RS24790	COG0673	inositol 2-dehydrogenase activity
VAB18032_RS24820	COG0586	Pfam SNARE associated Golgi protein
VAB18032_RS24830	COG2382	esterase
VAB18032_RS24830	COG3507	Belongs to the glycosyl hydrolase 43 family
VAB18032_RS24830	COG3693	PFAM glycoside hydrolase, family 10
VAB18032_RS24835	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
VAB18032_RS24840	COG0446	pyridine nucleotide-disulphide oxidoreductase
VAB18032_RS24845	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
VAB18032_RS24855	COG1028	Short-chain dehydrogenase reductase Sdr
VAB18032_RS24865	COG1834	amidinotransferase
VAB18032_RS24870	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
VAB18032_RS24880	COG2154	pterin-4-alpha-carbinolamine dehydratase
VAB18032_RS24910	COG2815	serine threonine protein kinase
VAB18032_RS24910	COG0515	serine threonine protein kinase
VAB18032_RS24925	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
VAB18032_RS24930	COG2205	protein histidine kinase activity
VAB18032_RS24935	COG0745	RESPONSE REGULATOR receiver
VAB18032_RS24955	COG1131	(ABC) transporter
VAB18032_RS24965	COG0508	dehydrogenase complex catalyzes the overall conversion of
VAB18032_RS24965	COG0567	Dehydrogenase, E1 component
VAB18032_RS24975	COG0857	belongs to the CobB CobQ family
VAB18032_RS24975	COG0280	phosphate acetyltransferase
VAB18032_RS24980	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
VAB18032_RS25015	COG2172	sigma factor antagonist activity
VAB18032_RS25025	COG1597	lipid kinase activity
VAB18032_RS25040	COG0175	sulfate reduction
VAB18032_RS25060	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
VAB18032_RS25075	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
VAB18032_RS25080	COG5662	AntiSigma factor
VAB18032_RS25085	COG1595	DNA-templated transcription, initiation
VAB18032_RS25100	COG2135	peptidase activity
VAB18032_RS25105	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
VAB18032_RS25115	COG0483	inositol monophosphate 1-phosphatase activity
VAB18032_RS25125	COG0438	transferase activity, transferring glycosyl groups
VAB18032_RS25140	COG2197	response regulator
VAB18032_RS25155	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
VAB18032_RS25175	COG1615	UPF0182 protein
VAB18032_RS25180	COG3480	Lon protease (S16) C-terminal proteolytic domain
VAB18032_RS25205	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
VAB18032_RS25280	COG1278	Cold shock
VAB18032_RS25300	COG1611	Belongs to the LOG family
VAB18032_RS25305	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
VAB18032_RS25310	COG2171	N-acyltransferase activity
VAB18032_RS25315	COG1404	Belongs to the peptidase S8 family
VAB18032_RS25340	COG0287	Prephenate dehydrogenase
VAB18032_RS25355	COG0456	acetyltransferase
VAB18032_RS25370	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
VAB18032_RS25390	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VAB18032_RS25395	COG4608	Belongs to the ABC transporter superfamily
VAB18032_RS25400	COG0444	Belongs to the ABC transporter superfamily
VAB18032_RS25445	COG2226	methyltransferase
VAB18032_RS25455	COG2949	membrane
VAB18032_RS25460	COG0012	GTP binding
VAB18032_RS25475	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
VAB18032_RS25475	COG2169	Transcriptional regulator
VAB18032_RS25485	COG1132	(ABC) transporter
VAB18032_RS25490	COG0525	valine-tRNA ligase activity
VAB18032_RS25510	COG1131	(ABC) transporter
VAB18032_RS25520	COG0529	Catalyzes the synthesis of activated sulfate
VAB18032_RS25550	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
VAB18032_RS25555	COG0747	negative chemotaxis
VAB18032_RS25560	COG0601	transmembrane transport
VAB18032_RS25565	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VAB18032_RS25570	COG0444	Belongs to the ABC transporter superfamily
VAB18032_RS25575	COG4608	Belongs to the ABC transporter superfamily
VAB18032_RS25580	COG0138	bifunctional purine biosynthesis protein purh
VAB18032_RS25630	COG0045	succinate-CoA ligase (ADP-forming) activity
VAB18032_RS25635	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
VAB18032_RS25640	COG0739	heme binding
VAB18032_RS25645	COG0739	heme binding
VAB18032_RS25645	COG0741	lytic transglycosylase activity
VAB18032_RS25645	COG1196	nuclear chromosome segregation
VAB18032_RS25650	COG0488	(ABC) transporter
VAB18032_RS25660	COG1605	Chorismate mutase
VAB18032_RS25665	COG4608	Belongs to the ABC transporter superfamily
VAB18032_RS25670	COG0444	Belongs to the ABC transporter superfamily
VAB18032_RS25675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VAB18032_RS25680	COG0601	transmembrane transport
VAB18032_RS25690	COG2197	response regulator
VAB18032_RS25695	COG4585	Histidine kinase
VAB18032_RS25710	COG0688	phosphatidylethanolamine metabolic process
VAB18032_RS25715	COG1183	phosphatidylcholine synthase activity
VAB18032_RS25720	COG1051	belongs to the nudix hydrolase family
VAB18032_RS25735	COG0519	Catalyzes the synthesis of GMP from XMP
VAB18032_RS25735	COG0518	GMP synthase (glutamine-hydrolyzing) activity
VAB18032_RS25745	COG1316	TRANSCRIPTIONal
VAB18032_RS25755	COG0516	GMP reductase activity
VAB18032_RS25770	COG2197	response regulator
VAB18032_RS25780	COG0459	protein refolding
VAB18032_RS25785	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
VAB18032_RS25795	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
VAB18032_RS25810	COG4214	carbohydrate transport
VAB18032_RS25850	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
VAB18032_RS25860	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
VAB18032_RS25880	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
VAB18032_RS25890	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
VAB18032_RS25895	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
VAB18032_RS25900	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
VAB18032_RS25905	COG2223	nitrite transmembrane transporter activity
VAB18032_RS25920	COG0243	molybdopterin cofactor binding
VAB18032_RS25925	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
VAB18032_RS25930	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
VAB18032_RS25930	COG2146	nitrite reductase [NAD(P)H] activity
VAB18032_RS25955	COG2018	Roadblock/LC7 domain
VAB18032_RS25970	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
VAB18032_RS26000	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
VAB18032_RS26005	COG0351	phosphomethylpyrimidine kinase
VAB18032_RS26010	COG0352	thiamine-phosphate diphosphorylase activity
VAB18032_RS26015	COG2022	thiamine diphosphate biosynthetic process
VAB18032_RS26030	COG0352	thiamine-phosphate diphosphorylase activity
VAB18032_RS26040	COG3291	Pkd domain containing protein
VAB18032_RS26050	COG0667	Aldo Keto reductase
VAB18032_RS26055	COG0488	(ABC) transporter
VAB18032_RS26060	COG2813	Specifically methylates the guanine in position
VAB18032_RS26070	COG0101	tRNA pseudouridine synthase activity
VAB18032_RS26075	COG0203	ribosomal protein L17
VAB18032_RS26080	COG0202	RNA polymerase activity
VAB18032_RS26085	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
VAB18032_RS26090	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
VAB18032_RS26095	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
VAB18032_RS26100	COG0257	Belongs to the bacterial ribosomal protein bL36 family
VAB18032_RS26105	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
VAB18032_RS26120	COG0563	adenylate kinase activity
VAB18032_RS26130	COG0200	Binds to the 23S rRNA
VAB18032_RS26135	COG1841	ribosomal large subunit assembly
VAB18032_RS26140	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
VAB18032_RS26145	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
VAB18032_RS26150	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
VAB18032_RS26155	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
VAB18032_RS26160	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
VAB18032_RS26165	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
VAB18032_RS26170	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
VAB18032_RS26175	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
VAB18032_RS26180	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
VAB18032_RS26185	COG0255	Belongs to the universal ribosomal protein uL29 family
VAB18032_RS26190	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
VAB18032_RS26195	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
VAB18032_RS26200	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
VAB18032_RS26205	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
VAB18032_RS26210	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
VAB18032_RS26215	COG0089	rRNA binding
VAB18032_RS26220	COG0088	Forms part of the polypeptide exit tunnel
VAB18032_RS26225	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
VAB18032_RS26230	COG0051	transcription antitermination factor activity, RNA binding
VAB18032_RS26235	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
VAB18032_RS26240	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
VAB18032_RS26245	COG0049	tRNA binding
VAB18032_RS26250	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
VAB18032_RS26265	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
VAB18032_RS26270	COG0085	RNA polymerase activity
VAB18032_RS26275	COG0222	ribosome binding
VAB18032_RS26285	COG0081	regulation of translation
VAB18032_RS26290	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
VAB18032_RS26300	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
VAB18032_RS26315	COG2030	dehydratase
VAB18032_RS26320	COG0267	Belongs to the bacterial ribosomal protein bL33 family
VAB18032_RS26360	COG1666	GTP binding
VAB18032_RS26375	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
VAB18032_RS26385	COG0501	Belongs to the peptidase M48B family
VAB18032_RS26390	COG1007	ATP synthesis coupled electron transport
VAB18032_RS26395	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
VAB18032_RS26405	COG0713	ATP synthesis coupled electron transport
VAB18032_RS26415	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
VAB18032_RS26425	COG0435	Glutathione S-transferase
VAB18032_RS26430	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
VAB18032_RS26435	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
VAB18032_RS26440	COG1063	alcohol dehydrogenase
VAB18032_RS26450	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
VAB18032_RS26460	COG2211	Major facilitator Superfamily
VAB18032_RS26470	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
VAB18032_RS26475	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
VAB18032_RS26525	COG0513	Belongs to the DEAD box helicase family
VAB18032_RS26550	COG0514	ATP-dependent DNA helicase (RecQ)
VAB18032_RS26560	COG1028	Short-chain dehydrogenase reductase Sdr
VAB18032_RS26590	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
VAB18032_RS26595	COG0569	domain protein
VAB18032_RS26600	COG0515	serine threonine protein kinase
VAB18032_RS26615	COG0483	inositol monophosphate 1-phosphatase activity
VAB18032_RS26620	COG0784	Response regulator, receiver
VAB18032_RS26625	COG4251	negative regulation of phosphorylation
VAB18032_RS26630	COG0745	RESPONSE REGULATOR receiver
VAB18032_RS26665	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
VAB18032_RS26695	COG1674	ftsk spoiiie
VAB18032_RS26785	COG0488	(ABC) transporter
VAB18032_RS26790	COG2226	methyltransferase
VAB18032_RS26825	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
VAB18032_RS26825	COG1648	precorrin-2 dehydrogenase activity
VAB18032_RS26830	COG0181	hydroxymethylbilane synthase activity
VAB18032_RS26835	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
VAB18032_RS26840	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
VAB18032_RS26855	COG1595	DNA-templated transcription, initiation
VAB18032_RS26865	COG0560	Phosphoserine phosphatase
VAB18032_RS26885	COG1136	(ABC) transporter
VAB18032_RS26885	COG0577	efflux transmembrane transporter activity
VAB18032_RS26890	COG0577	efflux transmembrane transporter activity
VAB18032_RS26890	COG1136	(ABC) transporter
VAB18032_RS26910	COG0506	proline dehydrogenase activity
VAB18032_RS26920	COG0754	glutathionylspermidine amidase activity
VAB18032_RS26930	COG1082	Xylose isomerase domain protein TIM barrel
VAB18032_RS26960	COG0588	phosphoglycerate mutase activity
VAB18032_RS26985	COG0438	transferase activity, transferring glycosyl groups
VAB18032_RS27000	COG0812	UDP-N-acetylmuramate dehydrogenase activity
VAB18032_RS27020	COG0395	ABC-type sugar transport system, permease component
VAB18032_RS27035	COG0251	oxidation-reduction process
VAB18032_RS27045	COG1131	(ABC) transporter
VAB18032_RS27055	COG4585	Histidine kinase
VAB18032_RS27080	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
VAB18032_RS27110	COG3246	L-lysine catabolic process to acetate
VAB18032_RS27115	COG0354	folic acid binding
VAB18032_RS27120	COG0735	belongs to the Fur family
VAB18032_RS27130	COG4044	May play a role in the intracellular transport of hydrophobic ligands
VAB18032_RS27165	COG1404	Belongs to the peptidase S8 family
VAB18032_RS27165	COG4412	M6 family metalloprotease domain protein
VAB18032_RS27180	COG2897	thiosulfate sulfurtransferase activity
VAB18032_RS27195	COG0745	RESPONSE REGULATOR receiver
VAB18032_RS27205	COG0456	acetyltransferase
VAB18032_RS27250	COG2339	peptidase activity
VAB18032_RS27255	COG4129	membrane
VAB18032_RS27270	COG0277	FAD linked oxidase domain protein
VAB18032_RS27280	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
VAB18032_RS27285	COG1404	Belongs to the peptidase S8 family
VAB18032_RS27300	COG0459	protein refolding
VAB18032_RS27310	COG1278	Cold shock
VAB18032_RS27330	COG0454	-acetyltransferase
VAB18032_RS27330	COG0456	acetyltransferase
VAB18032_RS27335	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
VAB18032_RS27355	COG1131	(ABC) transporter
VAB18032_RS27370	COG2018	Roadblock/LC7 domain
VAB18032_RS27390	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
VAB18032_RS27415	COG1131	(ABC) transporter
VAB18032_RS27420	COG1349	DNA-binding transcription factor activity
VAB18032_RS27425	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
VAB18032_RS27475	COG1024	Enoyl-CoA hydratase
VAB18032_RS27485	COG3842	ATPase activity
VAB18032_RS27490	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
VAB18032_RS27495	COG0215	cysteine-tRNA ligase activity
VAB18032_RS27550	COG0114	fumarate hydratase activity
VAB18032_RS27565	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
VAB18032_RS27565	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
VAB18032_RS27590	COG3185	4-Hydroxyphenylpyruvate dioxygenase
VAB18032_RS27605	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
VAB18032_RS27640	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
VAB18032_RS27645	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
VAB18032_RS27675	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
VAB18032_RS27690	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
VAB18032_RS27695	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
VAB18032_RS27705	COG0242	peptide deformylase activity
VAB18032_RS27710	COG3830	Belongs to the UPF0237 family
VAB18032_RS27715	COG1194	a g-specific adenine glycosylase
VAB18032_RS27735	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
VAB18032_RS27740	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
VAB18032_RS27750	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
VAB18032_RS27760	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
VAB18032_RS27765	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
VAB18032_RS27780	COG0649	NAD binding
VAB18032_RS27790	COG1732	Glycine betaine
VAB18032_RS27795	COG1174	glycine betaine transport
VAB18032_RS27800	COG1174	glycine betaine transport
VAB18032_RS27870	COG0741	lytic transglycosylase activity
VAB18032_RS27870	COG0739	heme binding
VAB18032_RS27870	COG1196	nuclear chromosome segregation
VAB18032_RS27895	COG0302	gtp cyclohydrolase
VAB18032_RS27900	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
VAB18032_RS27910	COG4977	sequence-specific DNA binding
VAB18032_RS27915	COG0037	tRNA processing
VAB18032_RS27925	COG2027	D-alanyl-D-alanine carboxypeptidase
VAB18032_RS27930	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
VAB18032_RS27940	COG1674	ftsk spoiiie
VAB18032_RS27945	COG1404	Belongs to the peptidase S8 family
VAB18032_RS27950	COG0671	phosphoesterase, PA-phosphatase related
VAB18032_RS27965	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
VAB18032_RS27970	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
VAB18032_RS27975	COG2843	Capsule synthesis protein
VAB18032_RS28000	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
VAB18032_RS28025	COG2815	serine threonine protein kinase
VAB18032_RS28025	COG0515	serine threonine protein kinase
VAB18032_RS28075	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
VAB18032_RS28080	COG1610	YqeY-like protein
VAB18032_RS28085	COG1408	metallophosphoesterase
VAB18032_RS28105	COG2192	nodulation
VAB18032_RS28110	COG1280	lysine exporter protein (LysE YggA)
VAB18032_RS28140	COG0133	tryptophan synthase activity
VAB18032_RS28145	COG0159	tryptophan synthase activity
VAB18032_RS28150	COG2188	Transcriptional regulator
VAB18032_RS28185	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
VAB18032_RS28215	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
VAB18032_RS28220	COG0477	Major facilitator Superfamily
VAB18032_RS28235	COG4608	Belongs to the ABC transporter superfamily
VAB18032_RS28240	COG0444	Belongs to the ABC transporter superfamily
VAB18032_RS28245	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VAB18032_RS28250	COG0601	transmembrane transport
VAB18032_RS28255	COG0747	negative chemotaxis
VAB18032_RS28260	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
VAB18032_RS28265	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
VAB18032_RS28335	COG0506	proline dehydrogenase activity
VAB18032_RS28340	COG1012	belongs to the aldehyde dehydrogenase family
VAB18032_RS28375	COG0813	purine-nucleoside phosphorylase activity
VAB18032_RS28390	COG0590	tRNA wobble adenosine to inosine editing
VAB18032_RS28415	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
VAB18032_RS28415	COG1796	DNA polymerase
VAB18032_RS28420	COG0697	spore germination
VAB18032_RS28440	COG4981	capsule polysaccharide biosynthetic process
VAB18032_RS28450	COG0438	transferase activity, transferring glycosyl groups
VAB18032_RS28560	COG1674	ftsk spoiiie
VAB18032_RS28610	COG0464	growth
VAB18032_RS28645	COG1028	Short-chain dehydrogenase reductase Sdr
VAB18032_RS28700	COG0367	asparagine synthase
VAB18032_RS28705	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
VAB18032_RS28710	COG3546	catalase activity
VAB18032_RS28715	COG3693	PFAM glycoside hydrolase, family 10
VAB18032_RS28720	COG0577	efflux transmembrane transporter activity
VAB18032_RS28725	COG1136	(ABC) transporter
VAB18032_RS28810	COG1881	PFAM PEBP family protein
VAB18032_RS28815	COG0546	phosphoglycolate phosphatase activity
VAB18032_RS28840	COG1051	belongs to the nudix hydrolase family
VAB18032_RS28860	COG1674	ftsk spoiiie
VAB18032_RS28910	COG0789	Transcriptional regulator
VAB18032_RS28915	COG3959	Transketolase, thiamine diphosphate binding domain
VAB18032_RS28920	COG3958	Transketolase
VAB18032_RS28925	COG0463	Glycosyl transferase, family 2
VAB18032_RS28945	COG0183	Belongs to the thiolase family
VAB18032_RS28955	COG0705	Rhomboid family
VAB18032_RS28970	COG0598	Magnesium transport protein CorA
VAB18032_RS28975	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
VAB18032_RS28995	COG0371	Dehydrogenase
VAB18032_RS29015	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
VAB18032_RS29020	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
VAB18032_RS29025	COG3275	phosphorelay sensor kinase activity
VAB18032_RS29030	COG3279	Response regulator of the LytR AlgR family
VAB18032_RS29040	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
VAB18032_RS29070	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
VAB18032_RS29075	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
VAB18032_RS29105	COG5002	protein histidine kinase activity
VAB18032_RS29120	COG2235	arginine
VAB18032_RS29155	COG1764	response to oxidative stress
VAB18032_RS29165	COG0561	phosphatase activity
VAB18032_RS29170	COG0561	phosphatase activity
VAB18032_RS29190	COG1834	amidinotransferase
VAB18032_RS29195	COG1522	sequence-specific DNA binding
VAB18032_RS29220	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
VAB18032_RS29240	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
VAB18032_RS29250	COG1408	metallophosphoesterase
VAB18032_RS29310	COG0521	Mo-molybdopterin cofactor biosynthetic process
VAB18032_RS29315	COG0315	cyclic pyranopterin monophosphate synthase activity
VAB18032_RS29320	COG3629	intracellular signal transduction
VAB18032_RS29320	COG3903	Transcriptional regulator
VAB18032_RS29355	COG0359	binds to the 23S rRNA
VAB18032_RS29360	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
VAB18032_RS29370	COG0360	Binds together with S18 to 16S ribosomal RNA
VAB18032_RS29375	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
VAB18032_RS29390	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
VAB18032_RS29400	COG1695	Transcriptional regulator
VAB18032_RS29405	COG1260	myo-inositol-1-phosphate synthase
VAB18032_RS29415	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
VAB18032_RS29425	COG0617	tRNA 3'-terminal CCA addition
VAB18032_RS29440	COG1595	DNA-templated transcription, initiation
VAB18032_RS29455	COG3118	belongs to the thioredoxin family
VAB18032_RS29460	COG0860	N-Acetylmuramoyl-L-alanine amidase
VAB18032_RS29460	COG3409	Peptidoglycan-binding domain 1 protein
VAB18032_RS29470	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
VAB18032_RS29475	COG1181	Belongs to the D-alanine--D-alanine ligase family
VAB18032_RS29490	COG1192	Involved in chromosome partitioning
VAB18032_RS29495	COG0357	Ribosomal RNA small subunit methyltransferase G
VAB18032_RS29505	COG0706	membrane insertase activity
VAB18032_RS29510	COG0594	ribonuclease P activity
VAB18032_RS29515	COG0230	Belongs to the bacterial ribosomal protein bL34 family
VAB18032_RS29520	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
VAB18032_RS29525	COG0592	DNA-directed DNA polymerase activity
VAB18032_RS29530	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
VAB18032_RS29535	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
VAB18032_RS29540	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
VAB18032_RS29830	COG3973	AAA domain
VAB18032_RS29850	COG2226	methyltransferase
VAB18032_RS29860	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
VAB18032_RS29875	COG0443	Heat shock 70 kDa protein
VAB18032_RS29905	COG0789	Transcriptional regulator
VAB18032_RS29945	COG0297	glycogen (starch) synthase activity
VAB18032_RS30010	COG2201	protein-glutamate methylesterase activity
VAB18032_RS30025	COG0252	asparaginase activity
VAB18032_RS30085	COG0673	inositol 2-dehydrogenase activity
VAB18032_RS30090	COG3693	PFAM glycoside hydrolase, family 10
VAB18032_RS30100	COG3507	Belongs to the glycosyl hydrolase 43 family
VAB18032_RS30110	COG4585	Histidine kinase
VAB18032_RS30170	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
VAB18032_RS30185	COG0483	inositol monophosphate 1-phosphatase activity
VAB18032_RS30195	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
VAB18032_RS30255	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction