locus-tag	class	description
FR729_RS00020	ENOG4105C7H	Helicase, RecD TraA family
FR729_RS00035	ENOG4105DZR	Type I site-specific deoxyribonuclease
FR729_RS00045	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
FR729_RS00075	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
FR729_RS00090	ENOG4105CAF	HipA N-terminal domain protein
FR729_RS00140	ENOG4105CAF	HipA N-terminal domain protein
FR729_RS00150	ENOG4107RRE	RNA-directed DNA polymerase
FR729_RS00230	ENOG4105DFP	Integrase
FR729_RS00290	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
FR729_RS00295	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
FR729_RS00300	ENOG4105KTH	gatB Yqey
FR729_RS00305	ENOG4105VCC	30S ribosomal protein S21
FR729_RS00310	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
FR729_RS00315	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
FR729_RS00320	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
FR729_RS00325	ENOG4107ZVW	dihydroneopterin aldolase
FR729_RS00330	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FR729_RS00335	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
FR729_RS00340	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
FR729_RS00355	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
FR729_RS00360	ENOG4106MWK	domain protein
FR729_RS00365	ENOG4105CJ3	phosphate transporter
FR729_RS00370	ENOG4107IX6	phosphate transport regulator
FR729_RS00375	ENOG4105I7R	Adenylate cyclase
FR729_RS00385	ENOG4105C8Q	Methyl-accepting chemotaxis
FR729_RS00390	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
FR729_RS00395	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
FR729_RS00400	ENOG4105DFG	type I secretion outer membrane protein
FR729_RS00405	ENOG41087AY	ADP-Ribose pyrophosphatase
FR729_RS00410	ENOG4108SX3	cytoplasmic protein
FR729_RS00415	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
FR729_RS00420	ENOG4105IPS	esterase
FR729_RS00425	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
FR729_RS00430	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
FR729_RS00435	ENOG4105C0H	protease
FR729_RS00440	ENOG4105C0H	protease
FR729_RS00445	ENOG4108W2Q	Cytochrome d ubiquinol oxidase subunit III
FR729_RS00450	ENOG4105D6Z	AFG1 family ATPase
FR729_RS00455	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
FR729_RS00460	ENOG4108UJD	30S ribosomal protein S9
FR729_RS00465	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
FR729_RS00470	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
FR729_RS00475	ENOG4105EIX	cytochrome c1
FR729_RS00480	ENOG4107MKT	Stringent starvation protein a
FR729_RS00485	ENOG4105KB2	stringent starvation protein b
FR729_RS00490	ENOG4105W4M	Transport-associated protein
FR729_RS00495	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
FR729_RS00500	ENOG41082RQ	UPF0102 protein
FR729_RS00510	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
FR729_RS00520	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
FR729_RS00525	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
FR729_RS00530	ENOG4105CJN	penicillin-binding protein
FR729_RS00535	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
FR729_RS00540	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
FR729_RS00545	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
FR729_RS00550	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
FR729_RS00560	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
FR729_RS00565	ENOG4105DFU	Cell wall formation (By similarity)
FR729_RS00570	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
FR729_RS00575	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
FR729_RS00580	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
FR729_RS00585	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
FR729_RS00595	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
FR729_RS00600	ENOG4105M6F	mutator MutT protein
FR729_RS00605	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
FR729_RS00610	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
FR729_RS00615	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
FR729_RS00630	ENOG4105EJ9	Membrane
FR729_RS00635	ENOG4105VP0	transcriptional regulator, lysR family
FR729_RS00640	ENOG4105EN6	Membrane
FR729_RS00645	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
FR729_RS00650	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
FR729_RS00655	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
FR729_RS00665	ENOG4105BZ8	glutamate synthase
FR729_RS00670	ENOG4105CBC	glutamate synthase
FR729_RS00685	ENOG4105N5T	Radical SAM Protein
FR729_RS00695	ENOG4105BZU	Histidine kinase
FR729_RS00705	ENOG41065U4	response regulator
FR729_RS00715	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
FR729_RS00735	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
FR729_RS00740	ENOG4105D98	threonine synthase
FR729_RS00750	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
FR729_RS00755	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
FR729_RS00760	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
FR729_RS00775	ENOG4105BZG	amino acid carrier protein
FR729_RS00780	ENOG4105D1Q	UPF0246 protein
FR729_RS00785	ENOG4105C1J	atp-dependent rna helicase
FR729_RS00790	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
FR729_RS00795	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
FR729_RS00800	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
FR729_RS00810	ENOG4105T95	Thiol disulfide interChange protein
FR729_RS00815	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
FR729_RS00825	ENOG4105CRK	lysyL-tRNA synthetase
FR729_RS00830	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FR729_RS00840	ENOG4105CPC	Aldo Keto reductase
FR729_RS00850	ENOG4105IRT	Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair (By similarity)
FR729_RS00855	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
FR729_RS00860	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
FR729_RS00865	ENOG4105HF0	Membrane
FR729_RS00870	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
FR729_RS00875	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
FR729_RS00890	ENOG41063Z6	transcriptional regulator, lysR family
FR729_RS00895	ENOG41080HT	Transcriptional regulator, arsr family
FR729_RS00900	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
FR729_RS00905	ENOG4105CJR	Integral membrane protein (MviN
FR729_RS00910	ENOG4105DTN	riboflavin biosynthesis protein ribF
FR729_RS00915	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
FR729_RS00920	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
FR729_RS00925	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
FR729_RS00930	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
FR729_RS00940	ENOG4108NEV	two component transcriptional regulator, LytTR family
FR729_RS00945	ENOG4108HRK	Histidine kinase
FR729_RS00965	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FR729_RS00970	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
FR729_RS00975	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
FR729_RS00980	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
FR729_RS00985	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
FR729_RS00990	ENOG4105DR5	peptidase
FR729_RS01000	ENOG4105C5H	ABC transporter
FR729_RS01005	ENOG4107SC1	transglycosylase
FR729_RS01010	ENOG4105R9M	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity)
FR729_RS01015	ENOG4108K16	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
FR729_RS01025	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
FR729_RS01030	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
FR729_RS01035	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FR729_RS01040	ENOG4105C34	Pseudouridine synthase
FR729_RS01045	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
FR729_RS01050	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
FR729_RS01105	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
FR729_RS01110	ENOG4105CFP	Peptidase U32
FR729_RS01115	ENOG4105DH7	May be involved in recombination (By similarity)
FR729_RS01120	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
FR729_RS01125	ENOG4105BZU	Histidine kinase
FR729_RS01130	ENOG4105DJH	phosphate
FR729_RS01135	ENOG4105C9X	ppx gppa phosphatase
FR729_RS01140	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
FR729_RS01145	ENOG4105C8U	phosphate abc transporter
FR729_RS01150	ENOG4105E2Z	phosphate ABC transporter (Permease
FR729_RS01155	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
FR729_RS01165	ENOG4105CSR	polyphosphate kinase 2
FR729_RS01170	ENOG4106N3A	copper homeostasis protein cutc
FR729_RS01175	ENOG4105D3R	alkyl hydroperoxide reductase
FR729_RS01180	ENOG4105C5Q	Transcriptional regulator
FR729_RS01185	ENOG4107QP3	malate synthase g
FR729_RS01190	ENOG4108I9X	Isocitrate lyase
FR729_RS01195	ENOG4105W87	Cbs domain
FR729_RS01205	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
FR729_RS01210	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
FR729_RS01215	ENOG4105VIE	preprotein translocase, subunit YajC
FR729_RS01220	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
FR729_RS01225	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
FR729_RS01230	ENOG4105ECY	inositol monophosphatase
FR729_RS01235	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
FR729_RS01240	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
FR729_RS01245	ENOG4105C3J	Cysteine desulfurase
FR729_RS01250	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
FR729_RS01255	ENOG4108Z4V	iron-sulfur cluster assembly
FR729_RS01260	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
FR729_RS01265	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
FR729_RS01270	ENOG4108ZIT	Ferredoxin, 2FE-2S
FR729_RS01275	ENOG4105WVQ	Fe-S assembly protein IscX
FR729_RS01280	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
FR729_RS01285	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
FR729_RS01290	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
FR729_RS01300	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
FR729_RS01305	ENOG4105CUT	histidyl-tRNA synthetase
FR729_RS01310	ENOG4105N21	Membrane
FR729_RS01315	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
FR729_RS01320	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
FR729_RS01335	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
FR729_RS01340	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
FR729_RS01345	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
FR729_RS01350	ENOG4107S6Z	Na H antiporter
FR729_RS01360	ENOG4106HK8	GPR1 FUN34 yaaH family protein
FR729_RS01365	ENOG4105BZG	amino acid carrier protein
FR729_RS01370	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
FR729_RS01380	ENOG4108IQK	o-acetylhomoserine
FR729_RS01385	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
FR729_RS01405	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
FR729_RS01410	ENOG4105ETT	transcriptional Regulator, LysR family
FR729_RS01430	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
FR729_RS01435	ENOG4108Z1B	Cyclase dehydrase
FR729_RS01440	ENOG4105VDB	UPF0125 protein
FR729_RS01445	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
FR729_RS01455	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
FR729_RS01465	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
FR729_RS01470	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FR729_RS01475	ENOG4105CK2	sodium dicarboxylate symporter
FR729_RS01480	ENOG4105CFG	Acts as a chaperone (By similarity)
FR729_RS01485	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
FR729_RS01515	ENOG4105CFC	Transporter
FR729_RS01520	ENOG4108Z6B	deaminase
FR729_RS01525	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
FR729_RS01530	ENOG4108ETH	Formylglycinamide ribotide synthetase
FR729_RS01560	ENOG4105CIN	aminoacyl-histidine dipeptidase
FR729_RS01565	ENOG4105C7N	Xanthine uracil vitamin C permease
FR729_RS01570	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
FR729_RS01575	ENOG4108DJV	Fermentation respiration switch protein
FR729_RS01580	ENOG4108UVK	Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 (By similarity)
FR729_RS01585	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
FR729_RS01590	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
FR729_RS01595	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
FR729_RS01600	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
FR729_RS01620	ENOG4107YIM	Involved in the transcription termination process (By similarity)
FR729_RS01625	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
FR729_RS01630	ENOG4108ZAI	phosphatidylglycerophosphatase a
FR729_RS01635	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
FR729_RS01640	ENOG4105CTB	Polyprenyl synthetase
FR729_RS01645	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
FR729_RS01650	ENOG4105E14	MotA TolQ exbB proton channel
FR729_RS01655	ENOG4106VK6	Flagellar motor protein
FR729_RS01660	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
FR729_RS01665	ENOG4105ETT	transcriptional Regulator, LysR family
FR729_RS01675	ENOG4105M08	Membrane
FR729_RS01680	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
FR729_RS01685	ENOG4105CIQ	May have a role in processing of nucleic acids. It is probably not an exonuclease
FR729_RS01690	ENOG4105EWT	decarboxylase family
FR729_RS01705	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
FR729_RS01710	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
FR729_RS01715	ENOG4105EXF	Zn-ribbon-containing, possibly nucleic-acid-binding protein
FR729_RS01720	ENOG4105D01	(LipO)protein
FR729_RS01725	ENOG4108UMI	ABC transporter, permease
FR729_RS01730	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
FR729_RS01735	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
FR729_RS01740	ENOG4105D4X	repressor
FR729_RS01745	ENOG4105C5Y	PTS System
FR729_RS01750	ENOG4105CG3	alpha amylase, catalytic region
FR729_RS01765	ENOG4108JYZ	YitT family
FR729_RS01770	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
FR729_RS01775	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
FR729_RS01780	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
FR729_RS01785	ENOG4108Z43	UPF0250 protein
FR729_RS01790	ENOG4105DZ1	carboxypeptidase
FR729_RS01795	ENOG4105K6T	rare lipoprotein A
FR729_RS01800	ENOG4105CNI	cell division protein FtsW
FR729_RS01805	ENOG4105CJN	penicillin-binding protein
FR729_RS01810	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
FR729_RS01815	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
FR729_RS01820	ENOG4105DJF	DNA polymerase III, delta' subunit
FR729_RS01825	ENOG4108U2H	Rare lipoprotein B
FR729_RS01830	ENOG4105C8T	Leucyl-tRNA synthetase
FR729_RS01835	ENOG4107PAI	alpha helical protein
FR729_RS01840	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
FR729_RS01845	ENOG4108JU5	Magnesium and cobalt efflux protein
FR729_RS01850	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
FR729_RS01855	ENOG4105C9A	Phoh family
FR729_RS01860	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
FR729_RS01865	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
FR729_RS01970	ENOG4105C3G	gtp-binding protein
FR729_RS01975	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
FR729_RS01980	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
FR729_RS01985	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
FR729_RS01990	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
FR729_RS01995	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
FR729_RS02000	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
FR729_RS02005	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
FR729_RS02010	ENOG4108YY7	Invasion gene expression up-regulator SirB
FR729_RS02015	ENOG41063JG	Transcriptional regulator
FR729_RS02020	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
FR729_RS02025	ENOG4105CGH	5'-nucleotidase
FR729_RS02030	ENOG4108Z66	YbaK ebsC protein
FR729_RS02035	ENOG4105FE9	pseudouridine synthase
FR729_RS02040	ENOG4108DG9	Smr protein MutS2
FR729_RS02065	ENOG4105E2D	ec 3.2.1.52
FR729_RS02080	ENOG4105C59	p-type ATPase
FR729_RS02085	ENOG41081QG	Porin Gram-negative type
FR729_RS02095	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
FR729_RS02100	ENOG4105UYK	outer membrane protein a
FR729_RS02145	ENOG4107R88	Chemotaxis protein (CheV)
FR729_RS02150	ENOG4105BZU	Histidine kinase
FR729_RS02155	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
FR729_RS02160	ENOG4108ZC9	flagellar basal-body rod protein flgc
FR729_RS02165	ENOG4105W00	Flagellar hook capping protein
FR729_RS02170	ENOG4105BZE	flagellar hook protein, FlgE
FR729_RS02175	ENOG4108KPB	Flagellar basal-body rod protein FlgF
FR729_RS02180	ENOG4105CGA	flagellar basal-body rod protein FlgG
FR729_RS02185	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
FR729_RS02190	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
FR729_RS02195	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
FR729_RS02205	ENOG4105DTJ	flagellar hook-associated protein
FR729_RS02210	ENOG4105I03	Flagellin
FR729_RS02215	ENOG4105I03	Flagellin
FR729_RS02225	ENOG4105C5Y	PTS System
FR729_RS02230	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
FR729_RS02235	ENOG4105KZ7	phosphocarrier protein hpr
FR729_RS02240	ENOG4105C6T	cysteine synthase
FR729_RS02245	ENOG4105EXN	Sulfate transport protein CysZ
FR729_RS02250	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
FR729_RS02255	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
FR729_RS02275	ENOG4107QX8	SPFH domain, Band 7 family protein
FR729_RS02280	ENOG4107QR8	Thioredoxin
FR729_RS02285	ENOG4105E1F	short-chain dehydrogenase reductase
FR729_RS02290	ENOG4105ECP	epimerase
FR729_RS02320	ENOG4108RE9	Phosphodiesterase
FR729_RS02340	ENOG4108DQ1	activator toxR
FR729_RS02345	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
FR729_RS02350	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
FR729_RS02355	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
FR729_RS02360	ENOG4105DUX	Transporter
FR729_RS02365	ENOG4105MDZ	Transcriptional activator rfaH
FR729_RS02370	ENOG4105CAQ	asparagine synthetase
FR729_RS02375	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
FR729_RS02380	ENOG4105E2R	ROK family
FR729_RS02385	ENOG4105CE4	GlcNAc 6-P deacetylase
FR729_RS02390	ENOG4105CI1	PTS System
FR729_RS02395	ENOG4105CX6	glutaminyL-tRNA synthetase
FR729_RS02400	ENOG41090R7	Ferric uptake
FR729_RS02410	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
FR729_RS02420	ENOG4105EV9	Alpha Beta Hydrolase
FR729_RS02425	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
FR729_RS02430	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
FR729_RS02440	ENOG4107QNR	UPF0135 protein
FR729_RS02445	ENOG4105BZN	citrate synthase
FR729_RS02450	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
FR729_RS02455	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
FR729_RS02460	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
FR729_RS02465	ENOG4105E33	succinate dehydrogenase
FR729_RS02470	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
FR729_RS02475	ENOG4105C7S	Dehydrogenase
FR729_RS02480	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
FR729_RS02485	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
FR729_RS02490	ENOG4105FAV	ABC, transporter
FR729_RS02495	ENOG4105FDK	ABC transporter
FR729_RS02500	ENOG4105NXV	High-affinity zinc uptake system protein
FR729_RS02505	ENOG4107S4Z	Activates expression of the rhaBAD and rhaT operons (By similarity)
FR729_RS02510	ENOG4105XFK	Ferrous iron transport protein A
FR729_RS02515	ENOG4105CE1	Ferrous iron transport protein b
FR729_RS02530	ENOG4105C75	arginyL-tRNA synthetase
FR729_RS02535	ENOG4106ZCM	YecM protein
FR729_RS02545	ENOG4105NDH	peptidase s1 and s6 chymotrypsin hap
FR729_RS02550	ENOG4105CIY	formyltetrahydrofolate deformylase
FR729_RS02555	ENOG4105DVT	helicase
FR729_RS02560	ENOG41072GX	Peptidase M22 Glycoprotease
FR729_RS02570	ENOG4105R8X	Outer membrane lipoprotein Slp
FR729_RS02575	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
FR729_RS02580	ENOG4105CEY	Amp-dependent synthetase and ligase
FR729_RS02585	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
FR729_RS02595	ENOG4107QMS	site-determining protein
FR729_RS02600	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
FR729_RS02605	ENOG4105VNG	YcgL domain-containing protein
FR729_RS02610	ENOG4105CVE	Lytic murein transglycosylase
FR729_RS02620	ENOG4105D9N	nucleoside
FR729_RS02625	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
FR729_RS02635	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
FR729_RS02640	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
FR729_RS02645	ENOG4105C2D	reductase
FR729_RS02655	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
FR729_RS02680	ENOG4105C84	Histidine ammonia-lyase
FR729_RS02685	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
FR729_RS02690	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
FR729_RS02710	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
FR729_RS02745	ENOG4105C1J	atp-dependent rna helicase
FR729_RS02750	ENOG4107ZYR	domain protein
FR729_RS02770	ENOG4105CNG	UPF0061 protein
FR729_RS02775	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
FR729_RS02780	ENOG410835K	Tripartite ATP-Independent Periplasmic transporter DctQ
FR729_RS02785	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
FR729_RS02795	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FR729_RS02800	ENOG4105CQZ	Histidine kinase
FR729_RS02810	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
FR729_RS02815	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
FR729_RS02820	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
FR729_RS02825	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
FR729_RS02830	ENOG4105K70	DNA-binding protein
FR729_RS02835	ENOG4105EIN	peptidylprolyl cis-trans isomerase
FR729_RS02840	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
FR729_RS02855	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
FR729_RS02860	ENOG4105DK2	UPF0207 protein
FR729_RS02865	ENOG4105CHM	Aminotransferase
FR729_RS02870	ENOG4105E4F	Isochorismate synthase
FR729_RS02875	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
FR729_RS02885	ENOG4108IPT	Naphthoate synthase
FR729_RS02895	ENOG4105CEY	Amp-dependent synthetase and ligase
FR729_RS02905	ENOG4105HMI	Membrane
FR729_RS02910	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
FR729_RS02955	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
FR729_RS02960	ENOG4105BZS	acriflavin resistance protein
FR729_RS02980	ENOG4105C6T	cysteine synthase
FR729_RS02985	ENOG4108XM1	transcriptional regulator AsnC family
FR729_RS02995	ENOG4105C29	acyl-CoA thioesterase
FR729_RS03000	ENOG4108MNP	Glycoprotein polysaccharide metabolism
FR729_RS03015	ENOG4105BZU	Histidine kinase
FR729_RS03030	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
FR729_RS03040	ENOG4107SXA	Phosphorylase
FR729_RS03050	ENOG4108NVR	Methyl-accepting chemotaxis
FR729_RS03055	ENOG4105K59	histidine triad (HIT) protein
FR729_RS03080	ENOG4105D0Y	UPF0227 protein
FR729_RS03085	ENOG4105CEP	NADH dehydrogenase
FR729_RS03100	ENOG4108JA2	transcriptioN-repair coupling factor
FR729_RS03110	ENOG4105D60	lipoprotein releasing system transmembrane protein
FR729_RS03115	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
FR729_RS03120	ENOG4105D60	lipoprotein releasing system transmembrane protein
FR729_RS03130	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
FR729_RS03135	ENOG4105BZ1	(ABC) transporter
FR729_RS03140	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
FR729_RS03145	ENOG4105W49	UPF0434 protein
FR729_RS03150	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
FR729_RS03155	ENOG4105ED1	spovr family
FR729_RS03160	ENOG4106AKX	UPF0229 protein
FR729_RS03165	ENOG4105CYN	Serine protein kinase
FR729_RS03170	ENOG4105XWI	UPF0304 protein
FR729_RS03180	ENOG4105F1A	Pyruvate formate-lyase
FR729_RS03190	ENOG4105C6N	Formate acetyltransferase
FR729_RS03205	ENOG4108JEH	abc transporter atp-binding protein
FR729_RS03210	ENOG4105E89	ABC transporter
FR729_RS03215	ENOG4105DSP	amino acid AbC transporter
FR729_RS03230	ENOG4105CGK	Exodeoxyribonuclease III
FR729_RS03235	ENOG4106428	Protein of unknown function (DUF2496)
FR729_RS03240	ENOG4108URS	primosomal replication protein n''
FR729_RS03245	ENOG4105EJ9	Membrane
FR729_RS03250	ENOG4105DVT	helicase
FR729_RS03255	ENOG4105SDR	Outer membrane protein OmpT
FR729_RS03265	ENOG4108R99	pseudouridine synthase
FR729_RS03275	ENOG4105VEQ	Cold shock protein
FR729_RS03280	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
FR729_RS03285	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
FR729_RS03290	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
FR729_RS03295	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
FR729_RS03300	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
FR729_RS03310	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
FR729_RS03315	ENOG4105RKX	Protein of unknown function (DUF2498)
FR729_RS03320	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
FR729_RS03325	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
FR729_RS03330	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
FR729_RS03350	ENOG4105HP8	regulator of competence-specific genes
FR729_RS03355	ENOG4105ETE	Transcriptional regulator (LacI family
FR729_RS03360	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
FR729_RS03365	ENOG4106WF9	DNA-binding transcriptional regulator TorR
FR729_RS03370	ENOG4107S90	membrAne
FR729_RS03375	ENOG4106371	Methyltransferase
FR729_RS03380	ENOG4105GHU	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity)
FR729_RS03385	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
FR729_RS03390	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
FR729_RS03410	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
FR729_RS03415	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
FR729_RS03420	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
FR729_RS03425	ENOG41081XQ	Conserved Protein
FR729_RS03430	ENOG4105C9M	aspartyl-trna synthetase
FR729_RS03435	ENOG4105CDY	transcriptional regulatory protein
FR729_RS03440	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
FR729_RS03445	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
FR729_RS03450	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
FR729_RS03455	ENOG4105C4M	(Ubiquinol oxidase) subunit I
FR729_RS03460	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
FR729_RS03475	ENOG4107YD3	Thioesterase
FR729_RS03480	ENOG4105E02	MotA TolQ exbB proton channel
FR729_RS03485	ENOG4105M8F	Biopolymer transport protein exbD tolR
FR729_RS03495	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
FR729_RS03500	ENOG4105KCK	Peptidoglycan-associated lipoprotein
FR729_RS03505	ENOG4105UFD	tol-pal system protein YbgF
FR729_RS03510	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
FR729_RS03520	ENOG4105Z6B	inner membrane protein yjfl
FR729_RS03530	ENOG4106032	Glutathionylspermidine synthase
FR729_RS03540	ENOG4105BZU	Histidine kinase
FR729_RS03545	ENOG4108RNS	Exports L-alanine (By similarity)
FR729_RS03555	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
FR729_RS03560	ENOG4105C4M	(Ubiquinol oxidase) subunit I
FR729_RS03575	ENOG4105C8Q	Methyl-accepting chemotaxis
FR729_RS03580	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
FR729_RS03585	ENOG4105BZS	acriflavin resistance protein
FR729_RS03620	ENOG4108NVR	Methyl-accepting chemotaxis
FR729_RS03625	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
FR729_RS03635	ENOG4107R11	Transcriptional regulator
FR729_RS03645	ENOG4105DCF	alanine dehydrogenase
FR729_RS03650	ENOG4105EW9	transcriptional regulator AsnC family
FR729_RS03655	ENOG4105CNU	cell division protein FtsK
FR729_RS03660	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
FR729_RS03665	ENOG4105D1H	recombination factor protein RarA
FR729_RS03670	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
FR729_RS03675	ENOG4105KSC	Transcriptional regulator, TraR DksA family
FR729_RS03685	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
FR729_RS03690	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
FR729_RS03700	ENOG4105EWW	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
FR729_RS03710	ENOG4105D0M	Protease HtpX homolog
FR729_RS03720	ENOG4107FW0	short-chain dehydrogenase reductase
FR729_RS03735	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
FR729_RS03745	ENOG4105RHG	
FR729_RS03755	ENOG4107QTF	adenylosuccinate lyase
FR729_RS03760	ENOG41075W9	High frequency lysogenization protein HflD homolog
FR729_RS03765	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
FR729_RS03775	ENOG4107RE1	Inosine-guanosine kinase
FR729_RS03780	ENOG4108YX2	DNA-binding protein
FR729_RS03785	ENOG4107S6Z	Na H antiporter
FR729_RS03790	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FR729_RS03795	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
FR729_RS03800	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
FR729_RS03805	ENOG4105CIH	Imidazole acetol-phosphate transaminase
FR729_RS03825	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
FR729_RS03835	ENOG4105K5B	UPF0225 protein
FR729_RS03840	ENOG4105D58	Diguanylate phosphodiesterase
FR729_RS03845	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
FR729_RS03850	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
FR729_RS03855	ENOG4105C8N	cysteinyl-tRNA synthetase
FR729_RS03860	ENOG4107104	thymidine kinase
FR729_RS03890	ENOG4105TMB	Formate nitrite transporter
FR729_RS03910	ENOG4108J2R	molybdopterin oxidoreductase
FR729_RS03925	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
FR729_RS03935	ENOG4108JQ2	peptide transport system atp-binding protein
FR729_RS03940	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
FR729_RS03945	ENOG4108EU3	peptide transport system, permease
FR729_RS03950	ENOG4108EKA	peptide transport system, permease
FR729_RS03955	ENOG4108J59	Extracellular solute-binding protein, family 5
FR729_RS03960	ENOG4105E51	psp operon transcriptional activator
FR729_RS03965	ENOG41087YS	Phage shock protein A
FR729_RS03970	ENOG4105YYT	phage shock protein B
FR729_RS03975	ENOG4105FM1	phage shock protein C
FR729_RS03995	ENOG4108R3E	Dna-3-methyladenine glycosylase i
FR729_RS04005	ENOG4107IFA	Lipase (EC 3.1.1.3)
FR729_RS04010	ENOG4105C28	cystathionine
FR729_RS04015	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
FR729_RS04020	ENOG4105C8J	)-transporter
FR729_RS04025	ENOG4108W1A	pseudouridine synthase
FR729_RS04035	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
FR729_RS04040	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
FR729_RS04045	ENOG4108JUA	Transcriptional regulator
FR729_RS04055	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
FR729_RS04060	ENOG4108VGW	abc transporter atp-binding protein
FR729_RS04065	ENOG4105CXZ	ABC transporter, permease
FR729_RS04070	ENOG4105VNH	ABC transporter solute-binding protein
FR729_RS04080	ENOG4105XZD	Fe-S protein
FR729_RS04090	ENOG4105CGH	5'-nucleotidase
FR729_RS04100	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
FR729_RS04105	ENOG4105EB3	Histidine kinase
FR729_RS04110	ENOG4105ETX	regulatoR
FR729_RS04120	ENOG4105CFI	type iii restriction protein res subunit
FR729_RS04125	ENOG4105I08	Pseudouridine synthase
FR729_RS04130	ENOG4105C2C	drug resistance transporter, Bcr CflA
FR729_RS04140	ENOG4105CGD	Nad-dependent epimerase dehydratase
FR729_RS04145	ENOG4107QI1	Mate efflux family protein
FR729_RS04165	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
FR729_RS04170	ENOG41067SE	Tetr family transcriptional regulator
FR729_RS04175	ENOG4107QPN	acyl-Coa dehydrogenase
FR729_RS04180	ENOG4105RKW	reductase (By
FR729_RS04185	ENOG4105D0C	transport protein
FR729_RS04190	ENOG41090BQ	Glutaredoxin
FR729_RS04200	ENOG4106KNT	transcriptional regulator
FR729_RS04205	ENOG4105DY8	decarboxylase
FR729_RS04215	ENOG4105DWU	Membrane
FR729_RS04240	ENOG4105BZU	Histidine kinase
FR729_RS04250	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
FR729_RS04255	ENOG4105BZC	d-serine deaminase
FR729_RS04260	ENOG4108JJ8	(ABC) transporter
FR729_RS04265	ENOG4108JJ9	ABC, transporter
FR729_RS04270	ENOG4105C3M	thioredoxin reductase
FR729_RS04295	ENOG4105C8P	)-transporter
FR729_RS04300	ENOG4107GZ4	SanA protein
FR729_RS04305	ENOG4107R1I	NAD-dependent malic enzyme
FR729_RS04310	ENOG4105CQ7	ATP-dependent helicase
FR729_RS04325	ENOG4105C8V	SAICAR synthetase
FR729_RS04345	ENOG4105CDV	Ompa motb domain protein
FR729_RS04360	ENOG4105CQB	FAD linked oxidase domain protein
FR729_RS04375	ENOG4105C84	Histidine ammonia-lyase
FR729_RS04385	ENOG41088SP	formiminoglutamate hydrolase
FR729_RS04390	ENOG4105CI2	imidazolone-5-propionate hydrolase
FR729_RS04395	ENOG4105CZE	histidine utilization repressor
FR729_RS04410	ENOG4105C22	threonyL-tRNA synthetase
FR729_RS04415	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
FR729_RS04420	ENOG41082NX	50s ribosomal protein l35
FR729_RS04425	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
FR729_RS04430	ENOG4105K8R	UPF0145 protein
FR729_RS04465	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
FR729_RS04470	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
FR729_RS04480	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
FR729_RS04490	ENOG4105FQ6	thiopurine methyltransferase
FR729_RS04495	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
FR729_RS04500	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
FR729_RS04505	ENOG41067MG	lrgb family
FR729_RS04510	ENOG4105VAW	lrga family
FR729_RS04515	ENOG4105CJB	Exodeoxyribonuclease I
FR729_RS04520	ENOG4108ETY	sodium dicarboxylate symporter
FR729_RS04525	ENOG4105K4T	epimerase
FR729_RS04530	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
FR729_RS04535	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
FR729_RS04555	ENOG4107UI5	Transforms N(2)-succinylglutamate into succinate and glutamate (By similarity)
FR729_RS04560	ENOG4108IU2	vtamin B12-transporter permease
FR729_RS04565	ENOG41080WI	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity)
FR729_RS04585	ENOG4105F04	LysR family Transcriptional regulator
FR729_RS04595	ENOG4108VKG	metal-dependent hydrolase
FR729_RS04600	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
FR729_RS04630	ENOG4105CTU	Proline racemase
FR729_RS04645	ENOG4105CIF	Ornithine Cyclodeaminase
FR729_RS04650	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
FR729_RS04655	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
FR729_RS04665	ENOG4105D38	putrescine abc transporter
FR729_RS04675	ENOG4107MM9	BNR Asp-box repeat-containing protein
FR729_RS04685	ENOG4108JQ7	(ABC) transporter
FR729_RS04690	ENOG4105C3U	ABC transporter
FR729_RS04695	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
FR729_RS04700	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
FR729_RS04705	ENOG4107QSI	ABC, transporter
FR729_RS04710	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
FR729_RS04715	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
FR729_RS04720	ENOG4105F1J	Homogentisate 1,2-dioxygenase
FR729_RS04730	ENOG4108RXX	maleylacetoacetate isomerase
FR729_RS04780	ENOG4105VTN	Protein of unknown function (DUF1311)
FR729_RS04805	ENOG4105KK4	UPF0060 membrane protein
FR729_RS04820	ENOG4107S6Z	Na H antiporter
FR729_RS04825	ENOG4105CFQ	glutamine synthetase
FR729_RS04830	ENOG4108Z86	Glutamine amidotransferase
FR729_RS04835	ENOG4107VRI	Transcriptional regulator
FR729_RS04840	ENOG4105C26	Dehydrogenase
FR729_RS04845	ENOG4105CJP	fad dependent oxidoreductase
FR729_RS04855	ENOG4105DWY	Agmatine deiminase
FR729_RS04860	ENOG4105C26	Dehydrogenase
FR729_RS04865	ENOG4108JPW	Aminotransferase
FR729_RS04870	ENOG4105BZU	Histidine kinase
FR729_RS04880	ENOG4108ZT1	Transcriptional regulator
FR729_RS04885	ENOG4105MSB	protein, conserved in bacteria
FR729_RS04910	ENOG4105BZU	Histidine kinase
FR729_RS04915	ENOG4105BZU	Histidine kinase
FR729_RS04925	ENOG41090FY	type IV pilus biogenesis stability protein PilW
FR729_RS04930	ENOG4105CVG	Homoserine O-transsuccinylase
FR729_RS04945	ENOG4105D1S	lipid A biosynthesis
FR729_RS04950	ENOG4105CTD	carboxy-peptidase
FR729_RS04955	ENOG410829K	Lysine exporter protein (Lyse ygga)
FR729_RS04965	ENOG4105BZG	amino acid carrier protein
FR729_RS04990	ENOG4105E0M	Sulfatase
FR729_RS04995	ENOG4105GIJ	Glycine betaine
FR729_RS05000	ENOG4108HQS	Glycine betaine
FR729_RS05005	ENOG4108IJ7	Glycine betaine
FR729_RS05020	ENOG4105C94	Transporter
FR729_RS05025	ENOG4108Z24	l-2,4-diaminobutyric acid acetyltransferase
FR729_RS05030	ENOG4108JPW	Aminotransferase
FR729_RS05035	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
FR729_RS05040	ENOG4105CZK	Aspartate kinase
FR729_RS05050	ENOG4105ENH	Sulfatase
FR729_RS05065	ENOG4105C4X	radical SAM domain protein
FR729_RS05080	ENOG4105ENH	Sulfatase
FR729_RS05085	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
FR729_RS05095	ENOG4108JJA	ABC, transporter
FR729_RS05105	ENOG4105DFG	type I secretion outer membrane protein
FR729_RS05120	ENOG4105E98	transcriptional regulator DeoR family
FR729_RS05125	ENOG4105D9R	oxidoreductase
FR729_RS05130	ENOG41090KN	UPF0303 protein
FR729_RS05155	ENOG4105C8P	)-transporter
FR729_RS05165	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FR729_RS05170	ENOG4105BZU	Histidine kinase
FR729_RS05175	ENOG4105CPI	Metal Dependent Phosphohydrolase
FR729_RS05180	ENOG410829K	Lysine exporter protein (Lyse ygga)
FR729_RS05185	ENOG4105G0K	glycine radical enzyme YjjI family
FR729_RS05190	ENOG41076CZ	activating enzyme
FR729_RS05200	ENOG4105EE5	Membrane protein terC
FR729_RS05210	ENOG4105DHT	Metal Dependent Phosphohydrolase
FR729_RS05220	ENOG4105E0U	tyrosine-specific transport protein
FR729_RS05225	ENOG4105CPI	Metal Dependent Phosphohydrolase
FR729_RS05235	ENOG4105E0A	ABC, transporter
FR729_RS05240	ENOG4105J76	Periplasmic binding protein
FR729_RS05245	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
FR729_RS05250	ENOG4105E0K	tonB-dependent siderophore receptor
FR729_RS05260	ENOG4105BZ1	(ABC) transporter
FR729_RS05265	ENOG4105BZ1	(ABC) transporter
FR729_RS05270	ENOG4108VAU	general secretion pathway protein G
FR729_RS05280	ENOG4105CR8	Transcriptional regulator
FR729_RS05305	ENOG4105CFG	Acts as a chaperone (By similarity)
FR729_RS05310	ENOG4105CFG	Acts as a chaperone (By similarity)
FR729_RS05355	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
FR729_RS05360	ENOG4105CQ7	ATP-dependent helicase
FR729_RS05375	ENOG4105C94	Transporter
FR729_RS05390	ENOG4107R8N	Glycosyl transferase, family 2
FR729_RS05395	ENOG4105CPK	Glycosyl transferase (Group 1
FR729_RS05425	ENOG4107TYR	Glycosyl Transferase
FR729_RS05430	ENOG4107QPH	glycogen) synthase
FR729_RS05435	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FR729_RS05450	ENOG4107V1M	polysaccharide export protein
FR729_RS05460	ENOG41082AN	stage II sporulation protein
FR729_RS05475	ENOG4107QI1	Mate efflux family protein
FR729_RS05480	ENOG4108R6K	riboflavin synthase, subunit alpha
FR729_RS05500	ENOG4105BZU	Histidine kinase
FR729_RS05510	ENOG4107TT5	NLP P60 protein
FR729_RS05545	ENOG4106IUH	DTW domain containing protein
FR729_RS05550	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
FR729_RS05560	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
FR729_RS05565	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
FR729_RS05570	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
FR729_RS05585	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FR729_RS05590	ENOG4105BZU	Histidine kinase
FR729_RS05595	ENOG4105C5H	ABC transporter
FR729_RS05600	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
FR729_RS05620	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
FR729_RS05630	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
FR729_RS05635	ENOG4105QAX	Iron-sulfur
FR729_RS05670	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
FR729_RS05680	ENOG4107RUE	extracellular solute-binding protein family 1
FR729_RS05685	ENOG4108HM4	ABC transporter
FR729_RS05690	ENOG4105D38	putrescine abc transporter
FR729_RS05700	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
FR729_RS05720	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
FR729_RS05725	ENOG4105Q9Y	Universal stress protein
FR729_RS05730	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
FR729_RS05745	ENOG4105C59	p-type ATPase
FR729_RS05755	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
FR729_RS05770	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
FR729_RS05800	ENOG4108R9Q	Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain (By similarity)
FR729_RS05805	ENOG4105DAN	ATP-dependent protease
FR729_RS05810	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
FR729_RS05825	ENOG4105C5H	ABC transporter
FR729_RS05835	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
FR729_RS05840	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
FR729_RS05845	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
FR729_RS05850	ENOG4105C7I	Dehydrogenase
FR729_RS05860	ENOG4105CD8	aminopeptidase N
FR729_RS05870	ENOG4105CN1	protease
FR729_RS05875	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
FR729_RS05880	ENOG4108ZGC	gaf domain protein
FR729_RS05885	ENOG4105BZ1	(ABC) transporter
FR729_RS05890	ENOG4105H2K	paraquat-inducible protein a
FR729_RS05895	ENOG4105DY2	Paraquat-inducible protein b
FR729_RS05900	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
FR729_RS05920	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
FR729_RS05925	ENOG4108VPT	UPF0234 protein
FR729_RS05935	ENOG4107QXX	ABC transporter
FR729_RS05940	ENOG4105EZ7	amino acid ABC transporter
FR729_RS05945	ENOG4105DRP	amino acid AbC transporter
FR729_RS05950	ENOG4105CDA	abc transporter atp-binding protein
FR729_RS05955	ENOG4108MN8	Membrane
FR729_RS05965	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
FR729_RS05970	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
FR729_RS05975	ENOG4105C8Q	Methyl-accepting chemotaxis
FR729_RS05980	ENOG4105DR4	Methyltransferase
FR729_RS05995	ENOG4105CDV	Ompa motb domain protein
FR729_RS06015	ENOG4105CDV	Ompa motb domain protein
FR729_RS06025	ENOG410620I	Diguanylate cyclase
FR729_RS06030	ENOG4107HP6	Transcriptional regulator
FR729_RS06040	ENOG4105CV8	reductase
FR729_RS06045	ENOG4105HEI	LysR family (Transcriptional regulator
FR729_RS06055	ENOG4105HEI	LysR family (Transcriptional regulator
FR729_RS06060	ENOG4105F27	Major Facilitator
FR729_RS06075	ENOG41063TF	transcriptional regulator (AraC
FR729_RS06080	ENOG4108W2Y	isochorismatase
FR729_RS06085	ENOG4106PMH	Extracellular solute-binding protein family 3
FR729_RS06095	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
FR729_RS06100	ENOG4105C3R	Methionine synthase
FR729_RS06105	ENOG4105CDA	abc transporter atp-binding protein
FR729_RS06110	ENOG4105EAD	ABC transporter
FR729_RS06115	ENOG4106PMH	Extracellular solute-binding protein family 3
FR729_RS06130	ENOG4105CC0	LysR family Transcriptional regulator
FR729_RS06145	ENOG4105HEI	LysR family (Transcriptional regulator
FR729_RS06150	ENOG41090KR	LysR family transcriptional Regulator
FR729_RS06165	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
FR729_RS06170	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
FR729_RS06175	ENOG410667J	hydrolase
FR729_RS06185	ENOG4105NDH	peptidase s1 and s6 chymotrypsin hap
FR729_RS06195	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
FR729_RS06200	ENOG4105C7F	AcnD-accessory protein PrpF
FR729_RS06205	ENOG4108I0Z	Aconitate hydratase
FR729_RS06210	ENOG4105BZN	citrate synthase
FR729_RS06215	ENOG4105CR4	methylisocitrate lyase
FR729_RS06250	ENOG4105EJ9	Membrane
FR729_RS06255	ENOG4105H1G	trap transporter solute receptor taxi family
FR729_RS06365	ENOG4105E7U	AraC family transcriptional regulator
FR729_RS06435	ENOG41066XE	Type III export protein
FR729_RS06465	ENOG4108KB1	transcriptional regulator, arac family
FR729_RS06485	ENOG4105C26	Dehydrogenase
FR729_RS06490	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
FR729_RS06505	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
FR729_RS06510	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
FR729_RS06515	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
FR729_RS06530	ENOG4106YYS	transcriptional regulatory protein
FR729_RS06535	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
FR729_RS06550	ENOG4107V40	secretion protein, HlyD family
FR729_RS06565	ENOG4105DUM	transcriptional regulator, lysR family
FR729_RS06590	ENOG4105D0C	transport protein
FR729_RS06600	ENOG4105Y49	secretion protein, HlyD family
FR729_RS06615	ENOG4105EBR	Carboxylesterase
FR729_RS06620	ENOG4107RZC	phospholipase d
FR729_RS06625	ENOG4105CFU	surface antigen
FR729_RS06630	ENOG41090VV	Protein of unknown function (DUF2846)
FR729_RS06635	ENOG4105N14	lysine exporter protein LysE YggA
FR729_RS06640	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
FR729_RS06645	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
FR729_RS06665	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
FR729_RS06670	ENOG41068WN	
FR729_RS06675	ENOG4108UW5	maltose o-acetyltransferase
FR729_RS06840	ENOG410822N	TonB family
FR729_RS06895	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
FR729_RS07120	ENOG4105K4U	addiction module toxin, RelE StbE family
FR729_RS07640	ENOG4105D9U	N-acetyltransferase
FR729_RS07650	ENOG4106K28	UPF0283 membrane protein
FR729_RS07655	ENOG4105CM6	amino acid regulated cytosolic protein
FR729_RS07670	ENOG4105CRQ	synthase (Component I)
FR729_RS07685	ENOG4105P8F	nudix hydrolase
FR729_RS07690	ENOG4105C44	Serine transporter
FR729_RS07695	ENOG4105EJQ	L-serine dehydratase
FR729_RS07700	ENOG4105BZU	Histidine kinase
FR729_RS07710	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
FR729_RS07715	ENOG4105C8Q	Methyl-accepting chemotaxis
FR729_RS07720	ENOG4105C5S	asparaginyl-tRNA synthetase
FR729_RS07730	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
FR729_RS07745	ENOG4105CGF	Aromatic amino acid aminotransferase
FR729_RS07765	ENOG4105C8Q	Methyl-accepting chemotaxis
FR729_RS07770	ENOG4105C94	Transporter
FR729_RS07790	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
FR729_RS07800	ENOG4105CH5	extracellular solute-binding protein, family 7
FR729_RS07815	ENOG4105C5X	domain protein
FR729_RS07820	ENOG4105EAQ	(twin-arginine translocation) pathway signal
FR729_RS07825	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
FR729_RS07850	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
FR729_RS07860	ENOG4108DMF	Cytochrome C biogenesis protein
FR729_RS07865	ENOG4107QX9	Thiol disulfide interChange protein
FR729_RS07870	ENOG4105DA4	cytochrome c-type biogenesis protein
FR729_RS07875	ENOG4105DVI	reductase, NrfD
FR729_RS07880	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
FR729_RS07890	ENOG4105EAU	Plays a role in nitrite reduction (By similarity)
FR729_RS07905	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
FR729_RS07910	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
FR729_RS07915	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
FR729_RS07920	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
FR729_RS07945	ENOG4105D3D	Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine (By similarity)
FR729_RS07985	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
FR729_RS07990	ENOG4105WH1	Two component transcriptional regulator luxr family
FR729_RS07995	ENOG4105CQ2	DNA polymerase
FR729_RS08010	ENOG4108W5H	UPF0263 protein
FR729_RS08015	ENOG4105FE9	pseudouridine synthase
FR729_RS08025	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
FR729_RS08030	ENOG4105DB7	PHP domain protein
FR729_RS08040	ENOG4105CRQ	synthase (Component I)
FR729_RS08045	ENOG4105DDQ	anthranilate synthase
FR729_RS08050	ENOG4108I0Q	anthranilate phosphoribosyltransferase
FR729_RS08055	ENOG4105DK0	Indole-3-glycerol phosphate synthase
FR729_RS08060	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
FR729_RS08065	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
FR729_RS08070	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
FR729_RS08075	ENOG4105CEY	Amp-dependent synthetase and ligase
FR729_RS08080	ENOG4105CK2	sodium dicarboxylate symporter
FR729_RS08090	ENOG4105BZU	Histidine kinase
FR729_RS08100	ENOG4107835	probably involved in intracellular septation (By similarity)
FR729_RS08105	ENOG4105NAU	thioesterase Superfamily protein
FR729_RS08110	ENOG4105K9H	YciI-like protein
FR729_RS08120	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
FR729_RS08125	ENOG4105DZ2	Transcriptional regulator
FR729_RS08145	ENOG4105CCT	upf0313 protein
FR729_RS08165	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
FR729_RS08175	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
FR729_RS08180	ENOG41062D9	Histidine kinase
FR729_RS08195	ENOG4105JQN	Transcriptional regulator
FR729_RS08200	ENOG4105J12	Multidrug resistance protein mdtN
FR729_RS08225	ENOG41063TF	transcriptional regulator (AraC
FR729_RS08230	ENOG4108W2Y	isochorismatase
FR729_RS08235	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
FR729_RS08240	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
FR729_RS08245	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
FR729_RS08255	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
FR729_RS08270	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
FR729_RS08280	ENOG4105N6Y	Thioredoxin
FR729_RS08285	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
FR729_RS08295	ENOG4108ZXC	Two component transcriptional regulator, luxr family
FR729_RS08300	ENOG4106AFQ	Histidine kinase
FR729_RS08305	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
FR729_RS08310	ENOG4106WHD	Tetrathionate reductase
FR729_RS08315	ENOG4105DB1	molybdopterin oxidoreductase
FR729_RS08325	ENOG4105NQN	cytochrome C
FR729_RS08330	ENOG4105F1S	paraquat-inducible protein a
FR729_RS08335	ENOG4105DY2	Paraquat-inducible protein b
FR729_RS08355	ENOG4108J59	Extracellular solute-binding protein, family 5
FR729_RS08360	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
FR729_RS08365	ENOG4105CFV	Tetratricopeptide repeat protein
FR729_RS08370	ENOG4105Q4A	inner membrane protein yciS
FR729_RS08375	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
FR729_RS08380	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
FR729_RS08385	ENOG4105CAT	Cytidine monophosphate kinase
FR729_RS08390	ENOG4105ERU	peptidase
FR729_RS08395	ENOG4105UBK	short-chain dehydrogenase reductase
FR729_RS08410	ENOG4105C0B	DNA polymerase III (alpha subunit)
FR729_RS08420	ENOG4105DAG	ROK family
FR729_RS08425	ENOG4105CA9	Pyruvate kinase
FR729_RS08430	ENOG4108NRW	Phospholipase, patatin family
FR729_RS08445	ENOG4105C8J	)-transporter
FR729_RS08460	ENOG4105CI1	PTS System
FR729_RS08465	ENOG4105F8V	Hydrolase, tatD family
FR729_RS08470	ENOG4105C6E	dna polymerase iii
FR729_RS08475	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
FR729_RS08480	ENOG4105HHA	aminodeoxychorismate lyase
FR729_RS08490	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
FR729_RS08495	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
FR729_RS08500	ENOG4105CHR	reductase
FR729_RS08505	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
FR729_RS08510	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
FR729_RS08515	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
FR729_RS08520	ENOG4105VGS	50s ribosomal protein l32
FR729_RS08525	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
FR729_RS08530	ENOG4108UHJ	MAF-like protein
FR729_RS08535	ENOG4105EI2	Pseudouridine synthase
FR729_RS08540	ENOG4105C03	ribonuclease
FR729_RS08545	ENOG4105CHH	sulfate transporter
FR729_RS08555	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
FR729_RS08565	ENOG4105DBI	uridine monophosphokinase
FR729_RS08570	ENOG4105D1F	ATP-binding protein
FR729_RS08575	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
FR729_RS08585	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
FR729_RS08595	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
FR729_RS08600	ENOG4106RHG	Yeca family
FR729_RS08605	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
FR729_RS08610	ENOG4105BZU	Histidine kinase
FR729_RS08615	ENOG4107R28	alpha amylase, catalytic region
FR729_RS08620	ENOG4108JJB	ABC transporter
FR729_RS08625	ENOG4105C7J	ABC transporter, permease
FR729_RS08635	ENOG4105PQ6	UPF0208 membrane protein
FR729_RS08640	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
FR729_RS08645	ENOG4108DNC	Involved in acetate metabolism (By similarity)
FR729_RS08655	ENOG4105CHF	Glutathione S-transferase
FR729_RS08660	ENOG4108JQ7	(ABC) transporter
FR729_RS08665	ENOG4105C3U	ABC transporter
FR729_RS08670	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
FR729_RS08675	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
FR729_RS08680	ENOG4107QSI	ABC, transporter
FR729_RS08685	ENOG4108ZAF	Molybdopterin
FR729_RS08690	ENOG4105M00	molybdopterin converting factor, subunit 1
FR729_RS08695	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
FR729_RS08700	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
FR729_RS08705	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
FR729_RS08710	ENOG4105CHW	UPF0052 protein
FR729_RS08720	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FR729_RS08725	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
FR729_RS08735	ENOG4105C6N	Formate acetyltransferase
FR729_RS08740	ENOG4105DGN	Electron transport complex
FR729_RS08745	ENOG4108R3D	Electron transport complex
FR729_RS08755	ENOG4105D6A	Electron transport complex
FR729_RS08760	ENOG4108UQQ	Electron transport complex
FR729_RS08765	ENOG4105DZB	Electron transport complex
FR729_RS08770	ENOG4105CSM	endonuclease III
FR729_RS08775	ENOG4108UYE	Lactoylglutathione lyase
FR729_RS08780	ENOG4106WH9	Protein of unknown function (DUF2753)
FR729_RS08785	ENOG4105EIY	sodium-type flagellar protein motY
FR729_RS08790	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
FR729_RS08795	ENOG4105D3Y	Na H antiporter
FR729_RS08805	ENOG4105M2J	Glutaredoxin
FR729_RS08810	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
FR729_RS08825	ENOG4105C0A	alcohol dehydrogenase
FR729_RS08830	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
FR729_RS08835	ENOG4105EYW	Ion transport protein
FR729_RS08840	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
FR729_RS08845	ENOG4105DFD	Na H antiporter
FR729_RS08860	ENOG4106V8H	Nucleoid-associated protein
FR729_RS08865	ENOG4105YDX	UPF0352 protein
FR729_RS08870	ENOG4105E68	Sulfatase
FR729_RS08880	ENOG4105DGU	Histone deacetylase
FR729_RS08885	ENOG4108RU0	short-chain dehydrogenase reductase
FR729_RS08895	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
FR729_RS08900	ENOG41069NU	Nitroreductase
FR729_RS08910	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
FR729_RS08915	ENOG4105D07	Signal peptide peptidase, SppA
FR729_RS08920	ENOG4105HDK	L-asparaginase
FR729_RS08925	ENOG4105VUT	cytoplasmic protein
FR729_RS08935	ENOG4105E0X	reductase
FR729_RS08940	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
FR729_RS08945	ENOG4105DSB	aldose 1-epimerase
FR729_RS08950	ENOG4107SDU	Methyl-accepting chemotaxis
FR729_RS08955	ENOG4105DHI	Methyltransferase
FR729_RS08970	ENOG4105G6Z	alkaline phosphatase
FR729_RS08985	ENOG41067V3	Antibiotic biosynthesis monooxygenase
FR729_RS08995	ENOG4108ZZ3	UPF0260 protein
FR729_RS09000	ENOG4105Y3U	Transglycosylase-associated protein
FR729_RS09005	ENOG4105KRS	Proteinase inhibitor
FR729_RS09010	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
FR729_RS09015	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
FR729_RS09020	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
FR729_RS09025	ENOG4107QMP	dna polymerase iii subunits gamma and tau
FR729_RS09030	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
FR729_RS09035	ENOG4105WD1	Membrane
FR729_RS09040	ENOG4105I93	response regulator
FR729_RS09045	ENOG4105EJC	lysr family transcriptional regulator
FR729_RS09050	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
FR729_RS09055	ENOG4105E96	Colicin v production protein
FR729_RS09060	ENOG4108S3P	Sporulation domain protein
FR729_RS09065	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
FR729_RS09070	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
FR729_RS09075	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
FR729_RS09085	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
FR729_RS09090	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
FR729_RS09095	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
FR729_RS09100	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
FR729_RS09105	ENOG4105Q8W	reductase
FR729_RS09110	ENOG4105MH2	YfcL protein
FR729_RS09115	ENOG4108BPE	-transporting atpase
FR729_RS09120	ENOG4105EN6	Membrane
FR729_RS09125	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
FR729_RS09130	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
FR729_RS09135	ENOG4108DG9	Smr protein MutS2
FR729_RS09140	ENOG4108BY2	phosphohistidine phosphatase
FR729_RS09145	ENOG4107QXK	peptidase
FR729_RS09155	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
FR729_RS09160	ENOG4105CHU	acetyl-coa acetyltransferase
FR729_RS09175	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
FR729_RS09180	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
FR729_RS09185	ENOG410903C	(LipO)protein
FR729_RS09190	ENOG4105KWW	Biogenesis protein
FR729_RS09195	ENOG4108M1T	Cytochrome c-type biogenesis protein
FR729_RS09200	ENOG4107QX9	Thiol disulfide interChange protein
FR729_RS09205	ENOG4105DA4	cytochrome c-type biogenesis protein
FR729_RS09210	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
FR729_RS09215	ENOG4105X3C	heme exporter protein
FR729_RS09220	ENOG41060IM	Heme exporter protein
FR729_RS09225	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
FR729_RS09230	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
FR729_RS09240	ENOG4108V3W	Chemotaxis protein, CheW
FR729_RS09250	ENOG4107QJE	Chromosome Partitioning Protein
FR729_RS09255	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
FR729_RS09265	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
FR729_RS09270	ENOG4108VYJ	response regulator receiver protein
FR729_RS09275	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
FR729_RS09285	ENOG4105FZW	flagellar biosynthesis regulator FlhF
FR729_RS09290	ENOG4105D7B	Flagellar biosynthesis protein flha
FR729_RS09295	ENOG4105D00	flagellar biosynthetic protein flhB
FR729_RS09300	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
FR729_RS09305	ENOG4105VS8	Flagellar biosynthetic protein fliq
FR729_RS09310	ENOG4105CN7	Flagellar biosynthetic protein FliP
FR729_RS09315	ENOG4105VTB	flagellar biosynthesis protein fliO
FR729_RS09320	ENOG4105DD5	Flagellar motor switch protein
FR729_RS09325	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
FR729_RS09350	ENOG4108JIR	Flagellum-specific ATP synthase
FR729_RS09360	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
FR729_RS09365	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
FR729_RS09370	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
FR729_RS09380	ENOG4105BZU	Histidine kinase
FR729_RS09390	ENOG4105MQ3	flagellar protein FliS
FR729_RS09400	ENOG4107BRV	flagellar capping protein
FR729_RS09405	ENOG41063QE	flagellar protein FlaG
FR729_RS09410	ENOG4105I03	Flagellin
FR729_RS09415	ENOG4105I03	Flagellin
FR729_RS09420	ENOG4105I03	Flagellin
FR729_RS09425	ENOG4105EZR	dyp-type peroxidase family protein
FR729_RS09430	ENOG4105QZU	Inner membrane protein YfeZ
FR729_RS09450	ENOG4105KUZ	arsenate reductase
FR729_RS09455	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
FR729_RS09470	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
FR729_RS09485	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FR729_RS09500	ENOG4105ERG	peptidase m48, ste24p
FR729_RS09505	ENOG4105K89	arsenate reductase
FR729_RS09510	ENOG4105CS1	NAD(P)H quinone oxidoreductase
FR729_RS09525	ENOG4105C2W	permease
FR729_RS09540	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
FR729_RS09545	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
FR729_RS09550	ENOG4105E7A	Glutamine amidotransferase
FR729_RS09555	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
FR729_RS09560	ENOG4107QPN	acyl-Coa dehydrogenase
FR729_RS09590	ENOG4107RZZ	dna polymerase iii epsilon subunit
FR729_RS09595	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
FR729_RS09600	ENOG4105D1A	Methyltransferase
FR729_RS09605	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
FR729_RS09610	ENOG4105E9H	Lytic Murein transglycosylase
FR729_RS09620	ENOG4107NA1	Endonuclease Exonuclease phosphatase
FR729_RS09625	ENOG4108YZA	Nitrogen regulatory protein pii
FR729_RS09630	ENOG4105N7H	Cytochrome
FR729_RS09635	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
FR729_RS09640	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
FR729_RS09645	ENOG4105C0B	DNA polymerase III (alpha subunit)
FR729_RS09650	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
FR729_RS09655	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
FR729_RS09660	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
FR729_RS09665	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
FR729_RS09670	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
FR729_RS09675	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
FR729_RS09685	ENOG4105DZP	Membrane-associated zinc metalloprotease
FR729_RS09690	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
FR729_RS09695	ENOG4105KNE	Phosphatidate cytidylyltransferase
FR729_RS09700	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
FR729_RS09705	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
FR729_RS09710	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
FR729_RS09715	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
FR729_RS09720	ENOG4105CE9	30S ribosomal protein S2
FR729_RS09725	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
FR729_RS09730	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
FR729_RS09735	ENOG4108T8E	UPF0325 protein
FR729_RS09740	ENOG4105DR9	pseudouridine synthase
FR729_RS09745	ENOG4105WP7	tRNA pseudouridine synthase C
FR729_RS09770	ENOG4108UPT	UPF0178 protein
FR729_RS09775	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
FR729_RS09780	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
FR729_RS09805	ENOG4105CFC	Transporter
FR729_RS09815	ENOG4105NRA	50s ribosomal protein l31 type b
FR729_RS09820	ENOG4108R96	Methyltransferase, YaeB family
FR729_RS09825	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
FR729_RS09835	ENOG4105W1I	UPF0253 protein
FR729_RS09845	ENOG4105C8J	)-transporter
FR729_RS09865	ENOG4105C9U	ATP-dependent DNA helicase RecQ
FR729_RS09870	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
FR729_RS09875	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
FR729_RS09905	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
FR729_RS09915	ENOG4105DZR	Type I site-specific deoxyribonuclease
FR729_RS09930	ENOG4105C7H	Helicase, RecD TraA family
FR729_RS09975	ENOG4105CJ2	(LipO)protein
FR729_RS09980	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
FR729_RS09985	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
FR729_RS09990	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
FR729_RS09995	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
FR729_RS10000	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
FR729_RS10005	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
FR729_RS10010	ENOG4105M85	Bola protein
FR729_RS10015	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
FR729_RS10020	ENOG4105IEY	(LipO)protein
FR729_RS10025	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
FR729_RS10040	ENOG4105K6V	RNA polymerase
FR729_RS10055	ENOG4105DRB	nucleoside-specific channel-forming protein
FR729_RS10060	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
FR729_RS10065	ENOG4107S0N	DJ-1 family
FR729_RS10070	ENOG4105C9B	Cysteine desulfurase
FR729_RS10075	ENOG4105BZU	Histidine kinase
FR729_RS10080	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
FR729_RS10085	ENOG4105CUZ	uba thif-type nad fad binding protein
FR729_RS10090	ENOG4105CA3	membrane-bound lytic murein transglycosylase
FR729_RS10100	ENOG4107QZM	n-acetylglutamate synthase
FR729_RS10120	ENOG4107QYX	exodeoxyribonuclease v alpha
FR729_RS10125	ENOG4107QKA	exodeoxyribonuclease V beta
FR729_RS10130	ENOG4105DSY	exodeoxyribonuclease V, gamma
FR729_RS10135	ENOG4105E68	Sulfatase
FR729_RS10145	ENOG4105EVZ	LysR family transcriptional regulator
FR729_RS10150	ENOG4105X2V	dna damage-inducible protein
FR729_RS10165	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
FR729_RS10170	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
FR729_RS10175	ENOG4105CXY	transporter
FR729_RS10180	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
FR729_RS10185	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
FR729_RS10190	ENOG4105E98	transcriptional regulator DeoR family
FR729_RS10195	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
FR729_RS10200	ENOG4107RX3	Mg2 transporter protein cora family protein
FR729_RS10220	ENOG4105CQ4	Transcriptional regulator
FR729_RS10225	ENOG41064T2	transcriptional regulator, lysR family
FR729_RS10315	ENOG4108IQE	Amp-dependent synthetase and ligase
FR729_RS10325	ENOG4105ETT	transcriptional Regulator, LysR family
FR729_RS10330	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
FR729_RS10335	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
FR729_RS10345	ENOG4105EAC	phosphoserine phosphatase
FR729_RS10355	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
FR729_RS10360	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
FR729_RS10365	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
FR729_RS10370	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
FR729_RS10375	ENOG4105D9N	nucleoside
FR729_RS10380	ENOG4105EYA	deoxyribonuclease
FR729_RS10390	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
FR729_RS10410	ENOG4108YYD	acetyltransferase
FR729_RS10420	ENOG4105BZU	Histidine kinase
FR729_RS10435	ENOG4105C3S	Mate efflux family protein
FR729_RS10450	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
FR729_RS10455	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
FR729_RS10460	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
FR729_RS10465	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
FR729_RS10470	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
FR729_RS10475	ENOG4105CHV	Transcription elongation factor NusA
FR729_RS10480	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
FR729_RS10495	ENOG4105NTZ	Preprotein translocase subunit SecG
FR729_RS10505	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
FR729_RS10510	ENOG4105EEI	dihydropteroate synthase
FR729_RS10515	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
FR729_RS10520	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
FR729_RS10525	ENOG4105HBR	Rna-binding protein
FR729_RS10530	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
FR729_RS10535	ENOG4107QE9	Inherit from COG: Membrane
FR729_RS10540	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
FR729_RS10550	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
FR729_RS10555	ENOG4105DR5	peptidase
FR729_RS10570	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
FR729_RS10575	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
FR729_RS10580	ENOG4105F4G	Membrane
FR729_RS10585	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
FR729_RS10595	ENOG4107QRA	Extracellular solute-binding protein, family 5
FR729_RS10605	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
FR729_RS10610	ENOG4105C3U	ABC transporter
FR729_RS10615	ENOG4108JQ7	(ABC) transporter
FR729_RS10625	ENOG4105RD7	BadF BadG BcrA BcrD
FR729_RS10630	ENOG4105E2D	ec 3.2.1.52
FR729_RS10645	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
FR729_RS10665	ENOG4108YZA	Nitrogen regulatory protein pii
FR729_RS10670	ENOG4105XTV	UPF0231 protein
FR729_RS10675	ENOG4107QIJ	Aconitate hydratase 2
FR729_RS10680	ENOG4105D78	K07001 NTE family protein
FR729_RS10685	ENOG4105BZ4	penicillin-binding protein
FR729_RS10690	ENOG4105CQ7	ATP-dependent helicase
FR729_RS10695	ENOG4105PW4	Sugar fermentation stimulation protein homolog
FR729_RS10700	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FR729_RS10705	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
FR729_RS10710	ENOG4105DJ0	Poly(A) Polymerase
FR729_RS10715	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FR729_RS10720	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
FR729_RS10725	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
FR729_RS10730	ENOG4105D1S	lipid A biosynthesis
FR729_RS10735	ENOG4105E3A	(ABC) transporter
FR729_RS10740	ENOG4105DA5	(ABC) transporter
FR729_RS10745	ENOG4105CHH	sulfate transporter
FR729_RS10750	ENOG41077A9	carbonic anhydrase
FR729_RS10755	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
FR729_RS10760	ENOG410630P	Transcriptional regulator
FR729_RS10765	ENOG4107QN2	dihydrolipoyl dehydrogenase
FR729_RS10770	ENOG4107QSN	dihydrolipoamide acetyltransferase
FR729_RS10775	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
FR729_RS10780	ENOG41073TP	transcriptional regulator
FR729_RS10790	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
FR729_RS10800	ENOG4107QHF	type ii secretion system protein e
FR729_RS10805	ENOG4105D7Q	type ii secretion system
FR729_RS10810	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
FR729_RS10815	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
FR729_RS10820	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
FR729_RS10825	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
FR729_RS10830	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
FR729_RS10835	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
FR729_RS10840	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
FR729_RS10845	ENOG4105K5M	30s ribosomal protein S16
FR729_RS10850	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FR729_RS10855	ENOG4106KVJ	cytochrome C assembly protein
FR729_RS10860	ENOG4108JU6	CBS domain protein
FR729_RS10875	ENOG4105D9M	gamma-glutamylcysteine synthetase
FR729_RS10885	ENOG4105W39	Membrane
FR729_RS10895	ENOG4105D9Q	decarboxylase (Beta subunit)
FR729_RS10900	ENOG4107QSA	Oxaloacetate decarboxylase
FR729_RS10960	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
FR729_RS10965	ENOG4105CFH	Aspartokinase
FR729_RS10970	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
FR729_RS10975	ENOG4105Y3E	Modulates RecA activity (By similarity)
FR729_RS10980	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
FR729_RS10985	ENOG4107TH8	cina domain protein
FR729_RS10990	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
FR729_RS10995	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
FR729_RS11005	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
FR729_RS11010	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
FR729_RS11015	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
FR729_RS11020	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
FR729_RS11025	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
FR729_RS11030	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
FR729_RS11035	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
FR729_RS11040	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
FR729_RS11045	ENOG4105DXN	mazG family
FR729_RS11050	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
FR729_RS11055	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
FR729_RS11060	ENOG4105BZU	Histidine kinase
FR729_RS11065	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
FR729_RS11070	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
FR729_RS11075	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
FR729_RS11080	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
FR729_RS11085	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
FR729_RS11090	ENOG4105C3F	Signal peptidase i
FR729_RS11095	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
FR729_RS11115	ENOG4105EMN	RNA polymerase sigma factor
FR729_RS11120	ENOG4108IYU	L-aspartate oxidase
FR729_RS11130	ENOG4105Y75	tpr repeat protein
FR729_RS11135	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
FR729_RS11150	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
FR729_RS11155	ENOG4105D0A	hydroxylase
FR729_RS11165	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
FR729_RS11175	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
FR729_RS11180	ENOG4105E66	phosphoriboisomerase A
FR729_RS11185	ENOG4108JQ1	Dehydrogenase
FR729_RS11190	ENOG4105MPN	Membrane
FR729_RS11195	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
FR729_RS11210	ENOG4105D64	Mechanosensitive ion channel
FR729_RS11215	ENOG4105D2N	Aldolase
FR729_RS11220	ENOG4105BZA	Phosphoglycerate kinase
FR729_RS11225	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
FR729_RS11230	ENOG4105D05	Receptor
FR729_RS11235	ENOG4108R4R	Iron-regulated virulence regulatory protein
FR729_RS11240	ENOG4105CV1	Transketolase (EC 2.2.1.1)
FR729_RS11245	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
FR729_RS11255	ENOG4105GPY	SprT protein
FR729_RS11260	ENOG4105RWS	endonuclease I
FR729_RS11265	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
FR729_RS11270	ENOG4105D7Z	glutathione synthase
FR729_RS11275	ENOG4108UJU	UPF0301 protein
FR729_RS11280	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
FR729_RS11285	ENOG4105CZX	twitching motility protein
FR729_RS11290	ENOG4105CZX	twitching motility protein
FR729_RS11295	ENOG4105DFA	alanine racemase domain protein
FR729_RS11300	ENOG4105II7	pyrroline-5-carboxylate reductase
FR729_RS11305	ENOG4108VIA	integral membrane protein
FR729_RS11310	ENOG4105VZ9	UPF0235 protein
FR729_RS11320	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
FR729_RS11325	ENOG4105CSA	Coproporphyrinogen iii oxidase
FR729_RS11330	ENOG4105CSV	Glutaminase
FR729_RS11340	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
FR729_RS11345	ENOG4105CEN	a g-specific adenine glycosylase
FR729_RS11350	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
FR729_RS11425	ENOG4105C26	Dehydrogenase
FR729_RS11470	ENOG4108ESY	Metal dependent phosphohydrolase
FR729_RS11475	ENOG4105ETE	Transcriptional regulator (LacI family
FR729_RS11480	ENOG410901P	UPF0249 protein
FR729_RS11485	ENOG4105F8D	glycoside hydrolase family 4
FR729_RS11490	ENOG4105VCP	PTS System
FR729_RS11495	ENOG4105CK1	PTS System
FR729_RS11500	ENOG4105VZJ	PTS System
FR729_RS11610	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
FR729_RS11625	ENOG4108K5H	permease YjgP YjgQ family protein
FR729_RS11630	ENOG4108M8S	permease YjgP YjgQ family protein
FR729_RS11635	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
FR729_RS11640	ENOG4105MYG	DNA polymerase iii, chi subunit
FR729_RS11645	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
FR729_RS11655	ENOG4108MJ3	acetyltransferase
FR729_RS11670	ENOG4105CEU	Arginine dihydrolase
FR729_RS11675	ENOG4105DBV	ornithine carbamoyltransferase
FR729_RS11685	ENOG4105CXT	aspartate transcarbamylase
FR729_RS11690	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
FR729_RS11695	ENOG4105KME	endoribonuclease L-psp
FR729_RS11700	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
FR729_RS11705	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
FR729_RS11710	ENOG4105VFK	BolA family
FR729_RS11720	ENOG4105E3I	toluene tolerance
FR729_RS11725	ENOG4107PE3	Mammalian cell entry related domain protein
FR729_RS11730	ENOG4105CY3	ABC transporter, permease
FR729_RS11735	ENOG4105DHJ	ABC, transporter
FR729_RS11745	ENOG4105C2X	Arabinose 5-phosphate isomerase
FR729_RS11755	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
FR729_RS11760	ENOG4108IUZ	ABC transporter
FR729_RS11765	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
FR729_RS11770	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
FR729_RS11775	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
FR729_RS11780	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
FR729_RS11785	ENOG41080Z8	PHOSPHOCARRIER protein
FR729_RS11790	ENOG4105CJW	magnesium transporter
FR729_RS11795	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
FR729_RS11800	ENOG4105N42	UPF0307 protein
FR729_RS11805	ENOG4105C5I	Dehydrogenase
FR729_RS11810	ENOG4105D3G	Pseudouridine synthase
FR729_RS11815	ENOG4105K3M	)-transporter
FR729_RS11820	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
FR729_RS11825	ENOG4108IAB	Phoh family
FR729_RS11830	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
FR729_RS11840	ENOG4105QD6	exported protein
FR729_RS11845	ENOG4105C03	ribonuclease
FR729_RS11850	ENOG4108Z03	MAF-like protein
FR729_RS11855	ENOG4105VQ7	Rod shape-determining protein MreD
FR729_RS11860	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
FR729_RS11900	ENOG4108VAU	general secretion pathway protein G
FR729_RS11910	ENOG4105D7Q	type ii secretion system
FR729_RS11915	ENOG4107QHF	type ii secretion system protein e
FR729_RS11950	ENOG41062P1	Diguanylate cyclase phosphodiesterase
FR729_RS11955	ENOG4108UUM	single-stranded DNA-binding protein
FR729_RS11960	ENOG41086KC	Transcriptional regulator
FR729_RS11965	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
FR729_RS11970	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
FR729_RS11980	ENOG4105C5R	Aminotransferase
FR729_RS11985	ENOG4105CFH	Aspartokinase
FR729_RS11990	ENOG4105C3R	Methionine synthase
FR729_RS11995	ENOG4105EEQ	Na H antiporter
FR729_RS12050	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
FR729_RS12055	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
FR729_RS12060	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
FR729_RS12080	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
FR729_RS12085	ENOG4105MYN	Zinc uptake regulation protein
FR729_RS12095	ENOG4107QP8	phosphohexose isomerase
FR729_RS12100	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
FR729_RS12105	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
FR729_RS12110	ENOG4105CDU	Replicative dna helicase
FR729_RS12120	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
FR729_RS12125	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
FR729_RS12130	ENOG4108VDV	Binds single-stranded DNA at the primosome assembly site (PAS) (By similarity)
FR729_RS12135	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
FR729_RS12140	ENOG4105DJV	ribulose-phosphate 3-epimerase
FR729_RS12145	ENOG4105DFE	Dna adenine methylase
FR729_RS12155	ENOG4105D49	3-dehydroquinate synthase
FR729_RS12160	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
FR729_RS12165	ENOG4105E4G	Type IV pilus
FR729_RS12190	ENOG4108JQC	penicillin-binding protein 1A
FR729_RS12195	ENOG4105C5Q	Transcriptional regulator
FR729_RS12200	ENOG4105EHV	domain protein
FR729_RS12205	ENOG4107QN2	dihydrolipoyl dehydrogenase
FR729_RS12215	ENOG4105CH7	arginosuccinase
FR729_RS12220	ENOG4105CDH	Citrulline--aspartate ligase
FR729_RS12225	ENOG4105CAS	nag kinase
FR729_RS12230	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
FR729_RS12235	ENOG4105CWC	Acetylornithine deacetylase
FR729_RS12240	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
FR729_RS12250	ENOG4105SYT	Methylenetetrahydrofolate reductase
FR729_RS12255	ENOG4105CFH	Aspartokinase
FR729_RS12260	ENOG4105C28	cystathionine
FR729_RS12265	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
FR729_RS12270	ENOG4105C6K	Malic enzyme
FR729_RS12275	ENOG4108UQY	Iron-storage protein
FR729_RS12280	ENOG4105W53	bacterioferritin-associated ferredoxin
FR729_RS12285	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
FR729_RS12290	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
FR729_RS12295	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
FR729_RS12300	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
FR729_RS12305	ENOG4105YKK	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
FR729_RS12310	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
FR729_RS12315	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
FR729_RS12320	ENOG4105WWK	YheO domain protein
FR729_RS12325	ENOG4108V1T	peptidylprolyl cis-trans isomerase
FR729_RS12335	ENOG41069P5	Protein slyX homolog
FR729_RS12340	ENOG4105D44	asparaginase
FR729_RS12345	ENOG4108YZY	peptidylprolyl cis-trans isomerase
FR729_RS12360	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
FR729_RS12365	ENOG4105C5H	ABC transporter
FR729_RS12375	ENOG4105DNZ	Alpha Beta Hydrolase
FR729_RS12380	ENOG4105YP7	UPF0270 protein
FR729_RS12385	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
FR729_RS12400	ENOG4105C26	Dehydrogenase
FR729_RS12410	ENOG4105C8Y	Acetylornithine aminotransferase
FR729_RS12415	ENOG4105DDQ	anthranilate synthase
FR729_RS12430	ENOG4105C31	Tryptophanyl-tRNA synthetase
FR729_RS12435	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
FR729_RS12440	ENOG4105C2N	RNA methyltransferase TrmH family group 3
FR729_RS12445	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
FR729_RS12450	ENOG4105KPV	Transcriptional regulator
FR729_RS12455	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
FR729_RS12460	ENOG4108UV7	flagellar protein motX
FR729_RS12465	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
FR729_RS12475	ENOG4105EPW	hflc protein
FR729_RS12480	ENOG4107QJR	hflk protein
FR729_RS12485	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
FR729_RS12490	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
FR729_RS12495	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
FR729_RS12500	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
FR729_RS12505	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
FR729_RS12510	ENOG4105K8N	protein family UPF0079, ATPase
FR729_RS12515	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
FR729_RS12580	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
FR729_RS12585	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
FR729_RS12590	ENOG4105DJ4	phosphatidylserine decarboxylase
FR729_RS12605	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
FR729_RS12610	ENOG4107YZP	Rhodanese domain protein
FR729_RS12615	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
FR729_RS12620	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
FR729_RS12625	ENOG4105D7W	serine acetyltransferase
FR729_RS12630	ENOG41063SB	peptidase
FR729_RS12640	ENOG41062JF	Transcriptional regulator
FR729_RS12650	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
FR729_RS12660	ENOG4105E33	succinate dehydrogenase
FR729_RS12665	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
FR729_RS12670	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
FR729_RS12680	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
FR729_RS12685	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
FR729_RS12690	ENOG4105KT7	mgtC SapB transporter
FR729_RS12700	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
FR729_RS12705	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
FR729_RS12715	ENOG4105CTQ	phosphohexokinase
FR729_RS12720	ENOG41076HS	cation diffusion facilitator family transporter
FR729_RS12725	ENOG4108SPG	Periplasmic Protein
FR729_RS12730	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
FR729_RS12735	ENOG4105E0F	Histidine kinase
FR729_RS12745	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
FR729_RS12750	ENOG4108YH1	overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7
FR729_RS12755	ENOG4108IJ0	Aspartate ammonia-lyase
FR729_RS12760	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
FR729_RS12765	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
FR729_RS12775	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
FR729_RS12785	ENOG4107QN1	sodium solute
FR729_RS12800	ENOG4105C9Q	fumarate hydratase class II
FR729_RS12805	ENOG4105BZU	Histidine kinase
FR729_RS12810	ENOG4105D8G	Major Facilitator superfamily
FR729_RS12825	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
FR729_RS12830	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
FR729_RS12835	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
FR729_RS12840	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
FR729_RS12845	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
FR729_RS12850	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
FR729_RS12855	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
FR729_RS12865	ENOG4105C5H	ABC transporter
FR729_RS12925	ENOG4105CXN	decarboxylase
FR729_RS12930	ENOG4105D5Q	Arginine ornithine antiporter
FR729_RS12935	ENOG4108M3R	transcriptional activator CadC
FR729_RS12940	ENOG4105W1Y	Transcriptional regulator
FR729_RS12945	ENOG4105DC1	bifunctional purine biosynthesis protein purh
FR729_RS12950	ENOG4105C12	Phosphoribosylglycinamide synthetase
FR729_RS12970	ENOG4105R2J	Conserved Protein
FR729_RS12975	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
FR729_RS12980	ENOG4108RG0	uracil-dna glycosylase
FR729_RS12985	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
FR729_RS12990	ENOG4105E09	nadh pyrophosphatase
FR729_RS12995	ENOG4108ZVW	Anti-RNA polymerase sigma 70 factor
FR729_RS13000	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
FR729_RS13005	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
FR729_RS13010	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
FR729_RS13015	ENOG4108VZM	50s ribosomal protein L10
FR729_RS13020	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
FR729_RS13025	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
FR729_RS13030	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
FR729_RS13035	ENOG4105PM1	preprotein translocase subunit SecE
FR729_RS13040	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
FR729_RS13065	ENOG4105CS9	pantothenic acid kinase
FR729_RS13070	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
FR729_RS13075	ENOG4105D4A	Cell wall formation (By similarity)
FR729_RS13085	ENOG4105JIM	Phosphatidylserine synthase
FR729_RS13115	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
FR729_RS13125	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
FR729_RS13155	ENOG4105DR5	peptidase
FR729_RS13170	ENOG4105EQR	Transposase IS116 IS110 IS902
FR729_RS13285	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
FR729_RS13300	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
FR729_RS13305	ENOG4107R73	Mate efflux family protein
FR729_RS13315	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
FR729_RS13320	ENOG4105E55	glycerol-3-phosphate acyltransferase
FR729_RS13325	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
FR729_RS13330	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
FR729_RS13335	ENOG4105X6C	Flagellar basal body-associated protein FliL
FR729_RS13340	ENOG4105EBW	Rhomboid-type serine protease that catalyzes intramembrane proteolysis (By similarity)
FR729_RS13345	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
FR729_RS13350	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
FR729_RS13355	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
FR729_RS13360	ENOG4105CAK	Cell division ATP-binding protein ftsE
FR729_RS13365	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
FR729_RS13370	ENOG4106H78	methyltransferase
FR729_RS13380	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
FR729_RS13425	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
FR729_RS13430	ENOG41082YX	Transcriptional regulator, arsr family
FR729_RS13435	ENOG4105D58	Diguanylate phosphodiesterase
FR729_RS13440	ENOG410829K	Lysine exporter protein (Lyse ygga)
FR729_RS13445	ENOG4108EUD	Lysophospholipase
FR729_RS13450	ENOG4105DQF	Hydrolase
FR729_RS13465	ENOG4106IUH	DTW domain containing protein
FR729_RS13470	ENOG4105BZU	Histidine kinase
FR729_RS13475	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
FR729_RS13480	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
FR729_RS13490	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
FR729_RS13495	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
FR729_RS13505	ENOG4105XQ6	frataxin-like protein
FR729_RS13510	ENOG4107T0K	Adenylate cyclase
FR729_RS13515	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
FR729_RS13520	ENOG41076E6	Uroporphyrinogen-III Synthase
FR729_RS13525	ENOG4105ECF	c-methyltransferase
FR729_RS13530	ENOG410601J	HemY protein
FR729_RS13565	ENOG4107QK7	reductase
FR729_RS13570	ENOG4108ZIT	Ferredoxin, 2FE-2S
FR729_RS13575	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
FR729_RS13585	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
FR729_RS13595	ENOG4105C1J	atp-dependent rna helicase
FR729_RS13600	ENOG4105C9X	ppx gppa phosphatase
FR729_RS13610	ENOG4105EX9	Membrane
FR729_RS13620	ENOG4105C9U	ATP-dependent DNA helicase RecQ
FR729_RS13625	ENOG4105FR1	rard protein
FR729_RS13635	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
FR729_RS13640	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
FR729_RS13645	ENOG4105C4R	Atp-dependent dna helicase
FR729_RS13655	ENOG4105E18	UPF0276 protein
FR729_RS13680	ENOG4105G2Y	Transcriptional regulator
FR729_RS13685	ENOG4105DC7	peptidase M24
FR729_RS13685	ENOG4105DC7	peptidase M24
FR729_RS13690	ENOG4105D41	biosynthesis protein thiH
FR729_RS13695	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
FR729_RS13700	ENOG4105WHD	thiamine biosynthesis protein ThiS
FR729_RS13705	ENOG4105D06	uba thif-type nad fad binding protein
FR729_RS13715	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
FR729_RS13720	ENOG4105WMR	Protein CrcB homolog
FR729_RS13725	ENOG4105E3B	Multicopper oxidase
FR729_RS13770	ENOG4108RR8	protoporphyrinogen oxidase
FR729_RS13775	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
FR729_RS13780	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
FR729_RS13785	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
FR729_RS13790	ENOG4105CHU	acetyl-coa acetyltransferase
FR729_RS13795	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
FR729_RS13810	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
FR729_RS13825	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
FR729_RS13830	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
FR729_RS13835	ENOG4107T9C	Alpha amylase catalytic region
FR729_RS13840	ENOG4105JKW	Valine--pyruvate aminotransferase
FR729_RS13845	ENOG4108ZNX	Heat shock protein
FR729_RS13855	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
FR729_RS13860	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
FR729_RS13865	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
FR729_RS13870	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
FR729_RS13875	ENOG4105EAB	amino acid AbC transporter
FR729_RS13880	ENOG4105E5Q	amino acid AbC transporter
FR729_RS13885	ENOG4105CDA	abc transporter atp-binding protein
FR729_RS13895	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
FR729_RS13905	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
FR729_RS13910	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
FR729_RS13915	ENOG4105QTB	Flavodoxin
FR729_RS13920	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
FR729_RS13925	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
FR729_RS13930	ENOG4107QJE	Chromosome Partitioning Protein
FR729_RS13935	ENOG4105FA0	parb-like partition protein
FR729_RS13940	ENOG410684E	atp synthase
FR729_RS13945	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
FR729_RS13950	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
FR729_RS13960	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
FR729_RS13965	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
FR729_RS13970	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
FR729_RS13975	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
FR729_RS13980	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
FR729_RS13985	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
FR729_RS13990	ENOG4105EAD	ABC transporter
FR729_RS13995	ENOG4105F87	Dehydratase
FR729_RS14000	ENOG4105CZQ	inner membrane transport protein YdhC
FR729_RS14005	ENOG4105F52	Transcriptional regulator
FR729_RS14010	ENOG4105C7B	Threonine dehydratase
FR729_RS14015	ENOG4105C01	Dihydroxy-acid dehydratase
FR729_RS14020	ENOG4105CM2	brancheD-chain amino acid aminotransferase
FR729_RS14025	ENOG4105P3Y	Acetolactate synthase 2 regulatory subunit
FR729_RS14035	ENOG4105C0P	Mg chelatase subunit ChlI
FR729_RS14045	ENOG4106HNH	Acyl-transferase
FR729_RS14050	ENOG4108Z33	Thiol disulfide Interchange Protein
FR729_RS14055	ENOG4105E27	serine threonine protein kinase
FR729_RS14065	ENOG4105PC1	Conserved Protein
FR729_RS14075	ENOG4108N23	SpoOM-related protein
FR729_RS14080	ENOG4108UT2	hemolysin iii
FR729_RS14090	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
FR729_RS14095	ENOG4105C1A	potassium transporter peripheral membrane
FR729_RS14100	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
FR729_RS14105	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
FR729_RS14120	ENOG4105C79	DNA protecting protein DprA
FR729_RS14125	ENOG4108RPN	Protein smg homolog
FR729_RS14130	ENOG4108WI1	Dna topoisomerase
FR729_RS14135	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
FR729_RS14140	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
FR729_RS14145	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
FR729_RS14150	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
FR729_RS14155	ENOG4105E2X	shikimate dehydrogenase
FR729_RS14160	ENOG4105SG3	Protein of unknown function (DUF1488)
FR729_RS14165	ENOG4108Z0R	Transferase
FR729_RS14200	ENOG4105EMY	transcriptional regulator
FR729_RS14210	ENOG4105W0Z	cytoplasmic protein
FR729_RS14215	ENOG4105BZS	acriflavin resistance protein
FR729_RS14220	ENOG410624X	efflux transporter, rnd family, mfp subunit
FR729_RS14225	ENOG41067SE	Tetr family transcriptional regulator
FR729_RS14230	ENOG4105C4R	Atp-dependent dna helicase
FR729_RS14235	ENOG4105MPD	Cytochrome
FR729_RS14275	ENOG4107QSI	ABC, transporter
FR729_RS14280	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
FR729_RS14285	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
FR729_RS14320	ENOG4105DIQ	Transcriptional regulator
FR729_RS14325	ENOG41064T2	transcriptional regulator, lysR family
FR729_RS14330	ENOG41090TI	Catalyzes the excretion of spermidine (By similarity)
FR729_RS14340	ENOG4105C01	Dihydroxy-acid dehydratase
FR729_RS14345	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
FR729_RS14350	ENOG4105C6Z	Gluconate
FR729_RS14355	ENOG4108UHU	Aldolase
FR729_RS14360	ENOG4107U5R	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
FR729_RS14365	ENOG4107RSM	transcriptional regulator
FR729_RS14370	ENOG4105DC8	reductase
FR729_RS14375	ENOG4105D6S	protein involved in catabolism of external DNA
FR729_RS14380	ENOG4105DGW	oligopeptidase A
FR729_RS14385	ENOG4108VVK	transcriptional Regulator, AsnC
FR729_RS14390	ENOG4105BZU	Histidine kinase
FR729_RS14395	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
FR729_RS14405	ENOG4105EMK	carboxylate amino acid amine transporter
FR729_RS14410	ENOG4108M6U	Universal stress protein A
FR729_RS14415	ENOG41090A1	ferritin
FR729_RS14420	ENOG4108V6B	universal stress protein B
FR729_RS14455	ENOG4105CBX	hi0933 family
FR729_RS14510	ENOG4105C4R	Atp-dependent dna helicase
FR729_RS14540	ENOG4108JUA	Transcriptional regulator
FR729_RS14565	ENOG4107TE5	Lipid kinase
FR729_RS14595	ENOG4105DSF	transport protein
FR729_RS14600	ENOG4105BZU	Histidine kinase
FR729_RS14610	ENOG4105CGY	Dna recombination protein
FR729_RS14615	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
FR729_RS14620	ENOG4105JC1	sterol-binding domain protein
FR729_RS14625	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
FR729_RS14630	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
FR729_RS14640	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
FR729_RS14645	ENOG4105F8V	Hydrolase, tatD family
FR729_RS14650	ENOG4105D52	delta-aminolevulinic acid dehydratase
FR729_RS14655	ENOG4105KD7	acetyltransferase
FR729_RS14660	ENOG4105C2M	dna polymerase I
FR729_RS14665	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
FR729_RS14670	ENOG4106RE7	Cytochrome
FR729_RS14680	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
FR729_RS14685	ENOG4105XCT	Protein of unknown function (DUF2489)
FR729_RS14690	ENOG4105D4P	Coproporphyrinogen iii oxidase
FR729_RS14695	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
FR729_RS14700	ENOG4105BZU	Histidine kinase
FR729_RS14705	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FR729_RS14710	ENOG4105CUX	Signal transduction histidine kinase
FR729_RS14720	ENOG4105C5F	glutamine synthetase
FR729_RS14725	ENOG4105CI3	gtp-binding protein typa
FR729_RS14730	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
FR729_RS14740	ENOG4107S2Z	UPF0761 membrane protein
FR729_RS14745	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
FR729_RS14750	ENOG4105SUU	thioesterase domain
FR729_RS14760	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
FR729_RS14765	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
FR729_RS14770	ENOG4105VEJ	Heat shock protein
FR729_RS14775	ENOG4108XKW	General secretion pathway protein C
FR729_RS14785	ENOG4107QHF	type ii secretion system protein e
FR729_RS14790	ENOG4105D7Q	type ii secretion system
FR729_RS14795	ENOG4108VAU	general secretion pathway protein G
FR729_RS14800	ENOG4105VWV	general secretion pathway protein h
FR729_RS14805	ENOG4105X5Z	General secretion pathway protein I
FR729_RS14810	ENOG4108WWZ	General secretion pathway protein J
FR729_RS14815	ENOG4108RTD	type II secretion system protein K
FR729_RS14820	ENOG4108BY5	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (By similarity)
FR729_RS14825	ENOG4105U1E	general secretion pathway protein M
FR729_RS14830	ENOG4105PIC	general secretion pathway protein N
FR729_RS14840	ENOG4107RK2	ADP-ribose diphosphatase NudE
FR729_RS14845	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
FR729_RS14850	ENOG4105MJ2	Competence protein
FR729_RS14855	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
FR729_RS14865	ENOG4105BZM	domain protein
FR729_RS14875	ENOG4108RRZ	Transcription elongation factor GreB
FR729_RS14890	ENOG4105E0F	Histidine kinase
FR729_RS14895	ENOG4105C2W	permease
FR729_RS14900	ENOG4105CB5	ATP-dependent DNA helicase recG
FR729_RS14905	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
FR729_RS14910	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
FR729_RS14915	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
FR729_RS14920	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
FR729_RS14935	ENOG4109015	Biopolymer transport protein exbD tolR
FR729_RS14960	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
FR729_RS14965	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
FR729_RS14970	ENOG4107QRA	Extracellular solute-binding protein, family 5
FR729_RS14980	ENOG4108JQ7	(ABC) transporter
FR729_RS15020	ENOG4108YGG	dna repair protein
FR729_RS15025	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
FR729_RS15035	ENOG4107SCJ	type I restriction enzyme EcoKI subunit R
FR729_RS15045	ENOG4107XZC	Restriction modification system DNA (Specificity
FR729_RS15065	ENOG4105DSJ	YicC domain protein
FR729_RS15070	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
FR729_RS15075	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
FR729_RS15080	ENOG4105D1S	lipid A biosynthesis
FR729_RS15085	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
FR729_RS15090	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
FR729_RS15095	ENOG4105C8Q	Methyl-accepting chemotaxis
FR729_RS15100	ENOG4105W5Q	DNA repair protein (RadC
FR729_RS15105	ENOG4105KDC	50s ribosomal protein l28
FR729_RS15120	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
FR729_RS15125	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
FR729_RS15130	ENOG4108JMC	lipopolysaccharide core biosynthesis protein
FR729_RS15140	ENOG4106WTF	Glycosyl transferase, family 2
FR729_RS15145	ENOG4105DKP	glycosyl transferase, family 9
FR729_RS15150	ENOG41080IJ	Diacylglycerol kinase
FR729_RS15155	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
FR729_RS15160	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
FR729_RS15165	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
FR729_RS15205	ENOG4105DF3	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity)
FR729_RS15210	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
FR729_RS15215	ENOG4105XA0	heptosyltransferase ii
FR729_RS15225	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
FR729_RS15230	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
FR729_RS15235	ENOG4105E3R	(LipO)protein
FR729_RS15260	ENOG4105DAY	polysaccharide export protein
FR729_RS15310	ENOG4105CY0	Metallo-Beta-Lactamase
FR729_RS15315	ENOG4105ESV	Glycosyl transferase, family 4
FR729_RS15335	ENOG4105CPK	Glycosyl transferase (Group 1
FR729_RS15355	ENOG4107T8Q	Glycosyl transferase (Group 1
FR729_RS15370	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
FR729_RS15375	ENOG4105CP7	Triose-phosphate isomerase
FR729_RS15405	ENOG4105CBT	Fructose-1,6-bisphosphatase
FR729_RS15410	ENOG41065UX	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
FR729_RS15415	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
FR729_RS15420	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
FR729_RS15425	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
FR729_RS15430	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
FR729_RS15440	ENOG4105ETE	Transcriptional regulator (LacI family
FR729_RS15445	ENOG4105C25	Primosomal protein n'
FR729_RS15450	ENOG4105VFB	Binds the 23S rRNA (By similarity)
FR729_RS15455	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
FR729_RS15460	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
FR729_RS15465	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
FR729_RS15470	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
FR729_RS15475	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FR729_RS15480	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
FR729_RS15485	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
FR729_RS15490	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
FR729_RS15495	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
FR729_RS15500	ENOG41083MP	50s ribosomal protein l29
FR729_RS15505	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
FR729_RS15510	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
FR729_RS15515	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
FR729_RS15520	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FR729_RS15525	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
FR729_RS15530	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
FR729_RS15535	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
FR729_RS15545	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
FR729_RS15550	ENOG4105VPB	50S ribosomal protein L30
FR729_RS15555	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
FR729_RS15560	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
FR729_RS15570	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FR729_RS15575	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
FR729_RS15580	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
FR729_RS15585	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
FR729_RS15590	ENOG4108ZT0	50S ribosomal protein l17
FR729_RS15600	ENOG4108V1T	peptidylprolyl cis-trans isomerase
FR729_RS15610	ENOG4107YB6	acetyltransferase, (GNAT) family
FR729_RS15615	ENOG4105C1J	atp-dependent rna helicase
FR729_RS15625	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
FR729_RS15630	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
FR729_RS15635	ENOG4105C11	sulfate adenylyltransferase), subunit 2
FR729_RS15640	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
FR729_RS15650	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
FR729_RS15670	ENOG4108I0Y	(ABC) transporter
FR729_RS15685	ENOG4108UUE	Transcriptional regulator
FR729_RS15690	ENOG41061GZ	Protein of unknown function (DUF1107)
FR729_RS15695	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
FR729_RS15700	ENOG4105CFU	surface antigen
FR729_RS15705	ENOG4105MA0	exported protein
FR729_RS15710	ENOG41066HZ	AIG2-like family
FR729_RS15720	ENOG4105F0N	pyrophosphate phospho-hydrolase
FR729_RS15725	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FR729_RS15730	ENOG4105DFU	Cell wall formation (By similarity)
FR729_RS15735	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
FR729_RS15745	ENOG4106SMU	thiamine transporter membrane protein
FR729_RS15750	ENOG4107T0D	ABC, transporter
FR729_RS15755	ENOG4105CC0	LysR family Transcriptional regulator
FR729_RS15760	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
FR729_RS15775	ENOG4105H1G	trap transporter solute receptor taxi family
FR729_RS15780	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
FR729_RS15785	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
FR729_RS15795	ENOG4105EAH	synthase
FR729_RS15800	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
FR729_RS15805	ENOG4105K46	50S ribosomal protein l27
FR729_RS15810	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FR729_RS15815	ENOG4105DWK	Membrane
FR729_RS15820	ENOG4107XM3	UPF0442 protein
FR729_RS15825	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
FR729_RS15830	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
FR729_RS15835	ENOG4105NWN	ApaG protein
FR729_RS15840	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
FR729_RS15845	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
FR729_RS15850	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
FR729_RS15855	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
FR729_RS15860	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
FR729_RS15870	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
FR729_RS15875	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
FR729_RS15880	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
FR729_RS15885	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
FR729_RS15905	ENOG41064T2	transcriptional regulator, lysR family
FR729_RS15910	ENOG4108IQE	Amp-dependent synthetase and ligase
FR729_RS15915	ENOG4105C7K	acetolactate synthase
FR729_RS15920	ENOG4108ZP8	Acetolactate synthase small subunit
FR729_RS15925	ENOG4105BZU	Histidine kinase
FR729_RS15935	ENOG4105CA9	Pyruvate kinase
FR729_RS15940	ENOG410804X	Transcriptional regulator
FR729_RS15945	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
FR729_RS15955	ENOG4105CMT	Dihydroxyacetone kinase
FR729_RS15960	ENOG4108UTZ	Dihydroxyacetone kinase
FR729_RS15975	ENOG4105E61	Mannitol repressor protein
FR729_RS15980	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
FR729_RS15985	ENOG4105CTS	PTS system mannitol-specific
FR729_RS16010	ENOG4105D01	(LipO)protein
FR729_RS16040	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
FR729_RS16045	ENOG4105CPQ	Dehydrogenase
FR729_RS16055	ENOG4105CHR	reductase
FR729_RS16065	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
FR729_RS16070	ENOG4105ENR	peptidase, M24
FR729_RS16075	ENOG4105E5N	succinylglutamate desuccinylase aspartoacylase
FR729_RS16080	ENOG4108RYR	transcriptional regulator AsnC family
FR729_RS16085	ENOG4105C26	Dehydrogenase
FR729_RS16090	ENOG4105C8Y	Acetylornithine aminotransferase
FR729_RS16095	ENOG4105IUQ	nucleoprotein polynucleotide-associated enzyme
FR729_RS16115	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
FR729_RS16120	ENOG4105HDK	L-asparaginase
FR729_RS16125	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
FR729_RS16140	ENOG4105WH1	Two component transcriptional regulator luxr family
FR729_RS16145	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
FR729_RS16150	ENOG4108HM4	ABC transporter
FR729_RS16200	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
FR729_RS16245	ENOG4107RZC	phospholipase d
FR729_RS16270	ENOG4108Z4X	TRANSCRIPTIONal
FR729_RS16280	ENOG4105RQF	LysR family Transcriptional regulator
FR729_RS16290	ENOG4107S8C	mandelate racemase muconate lactonizing
FR729_RS16295	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
FR729_RS16320	ENOG4105VYW	UPF0251 protein
FR729_RS16325	ENOG4107U14	binding-protein-dependent transport systems inner membrane Component
FR729_RS16330	ENOG4108IJ7	Glycine betaine
FR729_RS16335	ENOG4107EII	Lipoprotein involved with copper homeostasis and adhesion
FR729_RS16340	ENOG4105RW8	MltA-interacting MipA family protein
FR729_RS16355	ENOG4105ETT	transcriptional Regulator, LysR family
FR729_RS16380	ENOG4107RH7	Nicotinate phosphoribosyltransferase
FR729_RS16390	ENOG4108RWI	nicotinamidase
FR729_RS16405	ENOG4105N2W	Transcriptional regulator
FR729_RS16410	ENOG4108F19	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
FR729_RS16415	ENOG4105EA8	2-Nitropropane dioxygenase
FR729_RS16420	ENOG4105CUB	amino acid
FR729_RS16425	ENOG4107FQ9	ethanolamine ammonia-lyase
FR729_RS16430	ENOG4105CPD	ethanolamine ammonia-lyase
FR729_RS16435	ENOG4108K3Z	AraC family transcriptional regulator
FR729_RS16440	ENOG4107Z3H	Transcriptional regulator, TetR family
FR729_RS16460	ENOG4105N14	lysine exporter protein LysE YggA
FR729_RS16470	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
FR729_RS16475	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
FR729_RS16480	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
FR729_RS16495	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
FR729_RS16515	ENOG4105DTJ	flagellar hook-associated protein
FR729_RS16520	ENOG4105E1Q	flagellar hook-associated protein
FR729_RS16525	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
FR729_RS16530	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
FR729_RS16535	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
FR729_RS16540	ENOG4105CGA	flagellar basal-body rod protein FlgG
FR729_RS16545	ENOG4108KPB	Flagellar basal-body rod protein FlgF
FR729_RS16550	ENOG4105BZE	flagellar hook protein, FlgE
FR729_RS16555	ENOG4105W00	Flagellar hook capping protein
FR729_RS16560	ENOG4108ZC9	flagellar basal-body rod protein flgc
FR729_RS16565	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
FR729_RS16585	ENOG4105E4C	Lytic transglycosylase catalytic
FR729_RS16590	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
FR729_RS16610	ENOG4105EJQ	L-serine dehydratase
FR729_RS16625	ENOG4105ETT	transcriptional Regulator, LysR family
FR729_RS16630	ENOG4105UYK	outer membrane protein a
FR729_RS16640	ENOG4105CJP	fad dependent oxidoreductase
FR729_RS16650	ENOG4108MJ5	VirK protein
FR729_RS16670	ENOG4107RCV	ABC transporter, permease
FR729_RS16685	ENOG4107STF	Involved in phosphonate degradation (By similarity)
FR729_RS16690	ENOG4108JPW	Aminotransferase
FR729_RS16695	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
FR729_RS16700	ENOG4105ETE	Transcriptional regulator (LacI family
FR729_RS16730	ENOG4105KUU	lipolytic protein G-D-S-L family
FR729_RS16735	ENOG4105MKU	Transcriptional regulator
FR729_RS16750	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
FR729_RS16755	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
FR729_RS16760	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
FR729_RS16770	ENOG4108UUE	Transcriptional regulator
FR729_RS16785	ENOG4105PAD	Hydrolase
FR729_RS16790	ENOG4105JQN	Transcriptional regulator
FR729_RS16825	ENOG4108UW5	maltose o-acetyltransferase
FR729_RS16830	ENOG4108UKZ	OsmC family
FR729_RS16835	ENOG4105E0X	reductase
FR729_RS16850	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
FR729_RS16855	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
FR729_RS16860	ENOG4106TD9	Diguanylate cyclase
FR729_RS16875	ENOG4105BZU	Histidine kinase
FR729_RS16890	ENOG4105D9N	nucleoside
FR729_RS16910	ENOG4105C0F	tryptophanase EC 4.1.99.1
FR729_RS16915	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
FR729_RS16920	ENOG4105C4M	(Ubiquinol oxidase) subunit I
FR729_RS16925	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
FR729_RS16940	ENOG4105D5U	fad dependent oxidoreductase
FR729_RS16955	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
FR729_RS16960	ENOG4106TD9	Diguanylate cyclase
FR729_RS16965	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FR729_RS16995	ENOG4105DUM	transcriptional regulator, lysR family
FR729_RS17015	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
FR729_RS17020	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
FR729_RS17030	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
FR729_RS17035	ENOG4105CYW	agmatinase
FR729_RS17040	ENOG4105E5M	Multidrug resistance protein D
FR729_RS17045	ENOG4105CUG	Oligopeptidase b
FR729_RS17060	ENOG4105CC5	ABC transporter
FR729_RS17065	ENOG4105DIK	(ABC) transporter
FR729_RS17070	ENOG4105DSE	periplasmic solute binding protein
FR729_RS17110	ENOG4109015	Biopolymer transport protein exbD tolR
FR729_RS17135	ENOG410804D	Sensor Signal Transduction Histidine Kinase
FR729_RS17140	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
FR729_RS17145	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
FR729_RS17160	ENOG4108YYI	Protein of unknown function (DUF2810)
FR729_RS17215	ENOG4108TEM	pseudouridine methyltransferase
FR729_RS17230	ENOG4105DWF	phosphomethylpyrimidine kinase
FR729_RS17235	ENOG4108YI8	ABC transporter
FR729_RS17240	ENOG4105Y36	Binding-protein-dependent transport systems, inner membrane component
FR729_RS17245	ENOG4107Z6I	Thiamine biosynthesis protein
FR729_RS17250	ENOG4105ETU	transcriptional activator (TenA
FR729_RS17255	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
FR729_RS17260	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
FR729_RS17270	ENOG4107QY8	reductase
FR729_RS17275	ENOG4105CUW	cytochrome C-TYPE protein
FR729_RS17280	ENOG41068WN	
FR729_RS17285	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
FR729_RS17320	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
FR729_RS17325	ENOG4105BZW	Glycerate kinase
FR729_RS17330	ENOG4105C6Z	Gluconate
FR729_RS17335	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
FR729_RS17370	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
FR729_RS17385	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
FR729_RS17395	ENOG4105EIF	outer membrane protein W
FR729_RS17400	ENOG4107W31	Pentapeptide repeat protein
FR729_RS17415	ENOG4108M1A	Chitin-binding protein
FR729_RS17420	ENOG4105EW9	transcriptional regulator AsnC family
FR729_RS17430	ENOG4105Q26	Siderophore-interacting protein
FR729_RS17435	ENOG4105CC0	LysR family Transcriptional regulator
FR729_RS17440	ENOG4108MUX	N-hydroxyarylamine O-acetyltransferase
FR729_RS17460	ENOG4108KHX	Diguanylate cyclase
FR729_RS17470	ENOG4108HCJ	Hydrolase
FR729_RS17475	ENOG4105EJC	lysr family transcriptional regulator
FR729_RS17490	ENOG4105D3G	Pseudouridine synthase
FR729_RS17495	ENOG4105UQX	Mate efflux family protein
FR729_RS17500	ENOG4105BZU	Histidine kinase
FR729_RS17510	ENOG4105NBK	UPF0345 protein
FR729_RS17525	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
FR729_RS17540	ENOG4105DN9	Na H antiporter
FR729_RS17560	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
FR729_RS17565	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
FR729_RS17575	ENOG4108VGI	doxx family
FR729_RS17580	ENOG4105C2I	pirin domain protein
FR729_RS17600	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
FR729_RS17610	ENOG4105D6U	Sodium Glutamate Symporter
FR729_RS17615	ENOG4107U9B	transcriptional regulator
FR729_RS17620	ENOG4105CZV	ABC transporter
FR729_RS17630	ENOG4105D6U	Sodium Glutamate Symporter
FR729_RS17645	ENOG4105C8Q	Methyl-accepting chemotaxis
FR729_RS17650	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
FR729_RS17660	ENOG4108VAC	response regulator
FR729_RS17665	ENOG4108HRK	Histidine kinase
FR729_RS17685	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
FR729_RS17695	ENOG4105CNI	cell division protein FtsW
FR729_RS17700	ENOG4105CDY	transcriptional regulatory protein
FR729_RS17710	ENOG4105BZU	Histidine kinase
FR729_RS17735	ENOG4108JQ7	(ABC) transporter
FR729_RS17760	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
FR729_RS17775	ENOG4105EQ2	LysR family Transcriptional regulator
FR729_RS17780	ENOG4105EC3	peptidase S51, dipeptidase E
FR729_RS17785	ENOG4105FCK	Membrane
FR729_RS17790	ENOG4105C5Y	PTS System
FR729_RS17795	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FR729_RS17800	ENOG4108PSC	Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator (By similarity)
FR729_RS17810	ENOG4108J59	Extracellular solute-binding protein, family 5
FR729_RS17830	ENOG4108JJA	ABC, transporter
FR729_RS17845	ENOG4107QZV	Type I secretion membrane fusion protein
FR729_RS17850	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FR729_RS17855	ENOG4105CQZ	Histidine kinase
FR729_RS17860	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
FR729_RS17875	ENOG4105C26	Dehydrogenase
FR729_RS17885	ENOG4105CK7	Sodium proline symporter
FR729_RS17915	ENOG4105EW9	transcriptional regulator AsnC family
FR729_RS17925	ENOG4105BZ1	(ABC) transporter
FR729_RS17935	ENOG4105C1J	atp-dependent rna helicase
FR729_RS17940	ENOG4108RPX	mosc domain containing protein
FR729_RS17965	ENOG4105ECQ	AraC Family Transcriptional Regulator
FR729_RS17970	ENOG4105EXG	Transcriptional regulator
FR729_RS17990	ENOG4108JU3	Alkyl hydroperoxide reductase
FR729_RS17995	ENOG4105D3R	alkyl hydroperoxide reductase
FR729_RS18000	ENOG4105K56	Transcriptional regulator
FR729_RS18005	ENOG4108ZHJ	Organic hydroperoxide resistance protein
FR729_RS18045	ENOG4105C19	ABC transporter
FR729_RS18060	ENOG4105CKK	Glycosyl transferase, family 2
FR729_RS18090	ENOG4105CI1	PTS System
FR729_RS18100	ENOG4105DHQ	Histidine kinase
FR729_RS18105	ENOG4108JP0	extracellular solute-binding protein family 1
FR729_RS18110	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
FR729_RS18115	ENOG4105DBM	Siderophore biosynthesis protein
FR729_RS18125	ENOG4105DUU	IucA IucC family protein
FR729_RS18135	ENOG4105E0K	tonB-dependent siderophore receptor
FR729_RS18140	ENOG4105GAV	receptor
FR729_RS18145	ENOG4108HUF	Transporter
FR729_RS18150	ENOG4105DQ5	transport system permease protein
FR729_RS18155	ENOG4108U1V	ABC transporter, permease
FR729_RS18160	ENOG4105E0A	ABC, transporter
FR729_RS18165	ENOG4105C8Q	Methyl-accepting chemotaxis
FR729_RS18170	ENOG4107RAN	Peptidase, M16
FR729_RS18180	ENOG4105DR5	peptidase
FR729_RS18195	ENOG4105E5M	Multidrug resistance protein D
FR729_RS18205	ENOG4105ETE	Transcriptional regulator (LacI family
FR729_RS18210	ENOG4107RJ1	sodium solute
FR729_RS18225	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
FR729_RS18235	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
FR729_RS18240	ENOG4105ETE	Transcriptional regulator (LacI family
FR729_RS18245	ENOG4105CNV	Aldolase
FR729_RS18255	ENOG4105CHR	reductase
FR729_RS18290	ENOG4105EJQ	L-serine dehydratase
FR729_RS18300	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
FR729_RS18320	ENOG4108K8S	endonuclease I
FR729_RS18340	ENOG4105CXN	decarboxylase
FR729_RS18345	ENOG4105D5Q	Arginine ornithine antiporter
FR729_RS18355	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
FR729_RS18360	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
FR729_RS18365	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
FR729_RS18390	ENOG41061ZR	Transcriptional regulator
FR729_RS18395	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
FR729_RS18400	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
FR729_RS18405	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
FR729_RS18410	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
FR729_RS18415	ENOG4107T9C	Alpha amylase catalytic region
FR729_RS18430	ENOG41074DU	domain protein
FR729_RS18435	ENOG4108P2H	Inner membrane protein YjiG
FR729_RS18440	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
FR729_RS18460	ENOG4105CK2	sodium dicarboxylate symporter
FR729_RS18470	ENOG4105F04	LysR family Transcriptional regulator
FR729_RS18475	ENOG4105N0V	mono-oxygenase ydhR
FR729_RS18490	ENOG4105KJF	protein tyrosine phosphatase
FR729_RS18495	ENOG4105DAY	polysaccharide export protein
FR729_RS18510	ENOG41081FY	multiple antibiotic resistance (MarC)-related
FR729_RS18515	ENOG4108NRW	Phospholipase, patatin family
FR729_RS18520	ENOG4108M1A	Chitin-binding protein
FR729_RS18530	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
FR729_RS18540	ENOG4105C72	UPF0176 protein
FR729_RS18550	ENOG4105DZ1	carboxypeptidase
FR729_RS18560	ENOG4108ZX5	transcriptional regulator
FR729_RS18565	ENOG4108RCM	Nitroreductase
FR729_RS18575	ENOG4105ETT	transcriptional Regulator, LysR family
FR729_RS18580	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
FR729_RS18590	ENOG4105DP0	ferredoxin-NADP reductase
FR729_RS18600	ENOG41068P6	UPF0319 protein
FR729_RS18605	ENOG4105IPI	Membrane
FR729_RS18640	ENOG4105G2Y	Transcriptional regulator
FR729_RS18645	ENOG4105CNH	Multidrug resistance protein MdtL
FR729_RS18655	ENOG4105I4A	GCN5-related N-acetyltransferase
FR729_RS18665	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
FR729_RS18670	ENOG4105EB3	Histidine kinase
FR729_RS18685	ENOG4107T9Z	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
FR729_RS18690	ENOG4105F1A	Pyruvate formate-lyase
FR729_RS18715	ENOG4105KWG	Pfam:DUF1696
FR729_RS18730	ENOG4105ER2	Ompa motb domain protein
FR729_RS18735	ENOG4107RD7	Flagellar Motor Protein, MotA
FR729_RS18760	ENOG4105MQ3	flagellar protein FliS
FR729_RS18765	ENOG410804A	Flagellar hook-associated 2 domain-containing protein
FR729_RS18770	ENOG4105I03	Flagellin
FR729_RS18785	ENOG4105D00	flagellar biosynthetic protein flhB
FR729_RS18790	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
FR729_RS18795	ENOG4105VS8	Flagellar biosynthetic protein fliq
FR729_RS18800	ENOG4105CN7	Flagellar biosynthetic protein FliP
FR729_RS18805	ENOG4105DD5	Flagellar motor switch protein
FR729_RS18830	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
FR729_RS18835	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
FR729_RS18845	ENOG4108JIR	Flagellum-specific ATP synthase
FR729_RS18875	ENOG4107SSZ	Phosphatase
FR729_RS18895	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
FR729_RS18900	ENOG4105EXG	Transcriptional regulator
FR729_RS18920	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
FR729_RS18930	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
FR729_RS18945	ENOG4105BZU	Histidine kinase
FR729_RS18950	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
FR729_RS18955	ENOG4105CPQ	Dehydrogenase
FR729_RS18990	ENOG4105D64	Mechanosensitive ion channel
FR729_RS19000	ENOG4105DMF	Dehydrogenase
FR729_RS19005	ENOG4105DAA	L-lactate
FR729_RS19010	ENOG410642W	LysR family Transcriptional regulator
FR729_RS19020	ENOG4108JQ5	ABC transporter
FR729_RS19030	ENOG4105DAN	ATP-dependent protease
FR729_RS19040	ENOG4107QE9	Inherit from COG: Membrane
FR729_RS19045	ENOG4105YE1	PilZ domain
FR729_RS19060	ENOG4105WCN	acetyltransferase
FR729_RS19065	ENOG4108BGM	Quinol dehydrogenase periplasmic component
FR729_RS19070	ENOG4105GXZ	Ferredoxin-type protein NapH
FR729_RS19090	ENOG4108JJB	ABC transporter
FR729_RS19095	ENOG4108V7D	UPF0397 protein
FR729_RS19100	ENOG4105EFX	secretion protein, HlyD family
FR729_RS19105	ENOG4105KK7	inner membrane protein YiaW
FR729_RS19110	ENOG4105BZU	Histidine kinase
FR729_RS19125	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
FR729_RS19130	ENOG4107SEY	Conserved Protein
FR729_RS19135	ENOG4108XDN	Transcriptional regulator
FR729_RS19140	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
FR729_RS19145	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
FR729_RS19155	ENOG4105C1J	atp-dependent rna helicase
FR729_RS19160	ENOG4105CUG	Oligopeptidase b
FR729_RS19165	ENOG4107ENK	receptor
FR729_RS19185	ENOG4108NVR	Methyl-accepting chemotaxis
FR729_RS19195	ENOG4105C8U	phosphate abc transporter
FR729_RS19200	ENOG4105E2Z	phosphate ABC transporter (Permease
FR729_RS19205	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
FR729_RS19240	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
FR729_RS19245	ENOG4105C8Q	Methyl-accepting chemotaxis
FR729_RS19255	ENOG41086KC	Transcriptional regulator
FR729_RS19260	ENOG41086KC	Transcriptional regulator
FR729_RS19270	ENOG4108JJ6	Type I secretion system ATPase
FR729_RS19285	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
FR729_RS19290	ENOG4108HUF	Transporter
FR729_RS19295	ENOG4105E0A	ABC, transporter
FR729_RS19300	ENOG4105E0K	tonB-dependent siderophore receptor
FR729_RS19305	ENOG4105BZ1	(ABC) transporter
FR729_RS19325	ENOG4105CZN	Potassium uptake protein
FR729_RS19330	ENOG4105ETT	transcriptional Regulator, LysR family
FR729_RS19345	ENOG4105DVW	rieske (2Fe-2S)
FR729_RS19355	ENOG4107QZF	nitrite reductase NADPH large subunit
FR729_RS19360	ENOG4105CJP	fad dependent oxidoreductase
FR729_RS19375	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
FR729_RS19405	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
FR729_RS19410	ENOG4105CH6	catalase
FR729_RS19415	ENOG4108RXX	maleylacetoacetate isomerase
FR729_RS19420	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
FR729_RS19425	ENOG4108WUH	Transcriptional regulator, TetR family
FR729_RS19430	ENOG4105V0I	UPF0267 protein
FR729_RS19470	ENOG4105D75	Capsular exopolysaccharide family
FR729_RS19485	ENOG4105D3Q	Sugar transferase
FR729_RS19490	ENOG4108IJ9	(ABC) transporter
FR729_RS19495	ENOG4107FKK	extracellular solute-binding protein family 1
FR729_RS19500	ENOG4105D56	permease protein
FR729_RS19505	ENOG4105EG2	ABC transporter, permease
FR729_RS19535	ENOG4105CKW	Inner membrane protein yedI
FR729_RS19540	ENOG4105EKE	dihydroorotase
FR729_RS19550	ENOG4105QVC	MOSC domain-containing protein
FR729_RS19550	ENOG4105QVC	MOSC domain-containing protein
FR729_RS19555	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
FR729_RS19560	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
FR729_RS19600	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
FR729_RS19605	ENOG4105EHG	Permease protein
FR729_RS19615	ENOG4106GFD	transport protein
FR729_RS19620	ENOG41090AP	transport protein
FR729_RS19625	ENOG4105WQ5	TonB family
FR729_RS19630	ENOG4105D4P	Coproporphyrinogen iii oxidase
FR729_RS19635	ENOG41090JE	Utilization Protein
FR729_RS19640	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
FR729_RS19660	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
FR729_RS19665	ENOG4107R73	Mate efflux family protein
FR729_RS19670	ENOG4105C3U	ABC transporter
FR729_RS19675	ENOG4108JQ7	(ABC) transporter
FR729_RS19680	ENOG4105DEF	Extracellular solute-binding protein, family 5
FR729_RS19690	ENOG4105MVE	transcriptional regulator
FR729_RS19695	ENOG4105ZXK	Dehydrogenase
FR729_RS19700	ENOG4105G63	Type III effector Hrp-dependent
FR729_RS19705	ENOG4105FB2	class II Aldolase
FR729_RS19710	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
FR729_RS19715	ENOG4105EXW	epimerase dehydratase
FR729_RS19720	ENOG4105C6Z	Gluconate
FR729_RS19725	ENOG41090EM	Repressor of rcnA expression. Acts by binding specifically to the rcnA promoter in the absence of nickel and cobalt. In the presence of one of these metals, it has a weaker affinity for rcnA promoter
FR729_RS19730	ENOG41061MD	high-affinity nickel-transporter
FR729_RS19735	ENOG4105C8Q	Methyl-accepting chemotaxis
FR729_RS19740	ENOG4105CR8	Transcriptional regulator
FR729_RS19755	ENOG4105KXC	Collagenase
FR729_RS19765	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
FR729_RS19770	ENOG4105VUF	Transcriptional regulator
FR729_RS19790	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
FR729_RS19795	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
FR729_RS19800	ENOG4108M6U	Universal stress protein A
FR729_RS19805	ENOG4105C5H	ABC transporter
FR729_RS19820	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
FR729_RS19830	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
FR729_RS19840	ENOG4108HK0	-acetyltransferase
FR729_RS19865	ENOG4108IJF	Heavy metal efflux pump, CzcA
FR729_RS19885	ENOG4108IEG	Formate dehydrogenase Alpha subunit
FR729_RS19895	ENOG4107QWP	ABC-2 type transporter
FR729_RS19900	ENOG4105CJ1	ABC, transporter
FR729_RS19910	ENOG4105JAB	phenazine biosynthesis protein, phzf family
FR729_RS19915	ENOG4108V1U	phospholipid-binding protein
FR729_RS19925	ENOG4105D6J	arsenicaL-resistance protein
FR729_RS19940	ENOG4105KVH	Transcriptional regulator
FR729_RS19960	ENOG4105JQN	Transcriptional regulator
FR729_RS19965	ENOG4107RGM	aldo keto reductase
FR729_RS19990	ENOG4105E0U	tyrosine-specific transport protein
FR729_RS20000	ENOG4105C8Q	Methyl-accepting chemotaxis
FR729_RS20005	ENOG4105DWD	nucleoside recognition domain protein
FR729_RS20025	ENOG4105DR5	peptidase
FR729_RS20035	ENOG4105CR8	Transcriptional regulator
FR729_RS20040	ENOG4105E5M	Multidrug resistance protein D
FR729_RS20050	ENOG4105VW4	glutaredoxin 3
FR729_RS20055	ENOG4108SXK	Transporter Drug Metabolite Exporter family
FR729_RS20060	ENOG4105FCK	Membrane
FR729_RS20070	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
FR729_RS20090	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
FR729_RS20110	ENOG4105BZ9	Cytochrome C oxidase, subunit I
FR729_RS20115	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
FR729_RS20140	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
FR729_RS20145	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
FR729_RS20150	ENOG4108V1T	peptidylprolyl cis-trans isomerase
FR729_RS20160	ENOG4105CDV	Ompa motb domain protein
FR729_RS20180	ENOG4105VEQ	Cold shock protein
FR729_RS20185	ENOG4105VCN	Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system
FR729_RS20190	ENOG4105BZU	Histidine kinase
FR729_RS20195	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
FR729_RS20205	ENOG4105BZ1	(ABC) transporter
FR729_RS20215	ENOG4105DFG	type I secretion outer membrane protein
FR729_RS20220	ENOG4108MGY	Histidine kinase
FR729_RS20245	ENOG4105C8Q	Methyl-accepting chemotaxis
FR729_RS20250	ENOG4108RMU	ferritin dps family protein
FR729_RS20265	ENOG4105C0A	alcohol dehydrogenase
FR729_RS20270	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
FR729_RS20295	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
FR729_RS20300	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
FR729_RS20305	ENOG4105MIR	Phenylalanine 4-monooxygenase
FR729_RS20310	ENOG41090A4	Pterin carbinolamine dehydratase
FR729_RS20330	ENOG4105VRT	cytoplasmic protein
FR729_RS20345	ENOG4107YCY	Transcriptional regulator
FR729_RS20360	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
FR729_RS20370	ENOG4105HF0	Membrane
FR729_RS20380	ENOG4105C1J	atp-dependent rna helicase
FR729_RS20385	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
FR729_RS20395	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
FR729_RS20400	ENOG4105VEQ	Cold shock protein
FR729_RS20410	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
FR729_RS20420	ENOG4105CKI	cobalamin synthesis protein
FR729_RS20425	ENOG4105C1J	atp-dependent rna helicase
FR729_RS20445	ENOG4105CXC	rtn protein
FR729_RS20450	ENOG4105DKW	ABC transporter
FR729_RS20490	ENOG4108ENQ	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
FR729_RS20495	ENOG4105C1J	atp-dependent rna helicase
FR729_RS20500	ENOG4105BZU	Histidine kinase
FR729_RS20505	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
FR729_RS20510	ENOG4105EQ2	LysR family Transcriptional regulator
FR729_RS20515	ENOG4105ENX	hydrolase
FR729_RS20520	ENOG4105ENX	hydrolase
FR729_RS20540	ENOG4105J0Q	Transcriptional regulator
FR729_RS20550	ENOG4105II7	pyrroline-5-carboxylate reductase
FR729_RS20555	ENOG4107SDU	Methyl-accepting chemotaxis
FR729_RS20560	ENOG4105E90	ABC transporter
FR729_RS20565	ENOG4108IJ8	ABC transporter
FR729_RS20570	ENOG4108U0I	binding-protein-dependent transport systems inner membrane Component
FR729_RS20575	ENOG4107SI7	Substrate-binding region of abc-type glycine betaine transport system
FR729_RS20590	ENOG4105ECQ	AraC Family Transcriptional Regulator
FR729_RS20595	ENOG4107U2T	alpha beta
FR729_RS20605	ENOG4105CQB	FAD linked oxidase domain protein
FR729_RS20615	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
FR729_RS20620	ENOG4105E39	Enoyl-CoA hydratase
FR729_RS20625	ENOG4107QX3	carboxylase
FR729_RS20630	ENOG4105C1G	acyl-Coa dehydrogenase
FR729_RS20640	ENOG4105CHU	acetyl-coa acetyltransferase
FR729_RS20645	ENOG4105C26	Dehydrogenase
FR729_RS20655	ENOG4105E39	Enoyl-CoA hydratase
FR729_RS20660	ENOG4105E39	Enoyl-CoA hydratase
FR729_RS20665	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
FR729_RS20670	ENOG4105CHR	reductase
FR729_RS20675	ENOG4105E2S	oxidase) subunit II
FR729_RS20680	ENOG4105BZ9	Cytochrome C oxidase, subunit I
FR729_RS20685	ENOG4105CCU	oxidase (Subunit III)
FR729_RS20690	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
FR729_RS20695	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
FR729_RS20700	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
FR729_RS20715	ENOG4105C26	Dehydrogenase
FR729_RS20755	ENOG4105E5Z	arginine transporter ATP-binding subunit
FR729_RS20760	ENOG4106PMH	Extracellular solute-binding protein family 3
FR729_RS20765	ENOG4105GBT	ABC transporter
FR729_RS20770	ENOG4105DMR	ABC, transporter
FR729_RS20780	ENOG4105DUM	transcriptional regulator, lysR family
FR729_RS20795	ENOG4105EXG	Transcriptional regulator
FR729_RS20800	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
FR729_RS20805	ENOG4105C10	Electron transfer flavoprotein
FR729_RS20810	ENOG4107QSN	dihydrolipoamide acetyltransferase
FR729_RS20820	ENOG4107RUY	(E1 component), alpha subunit
FR729_RS20840	ENOG4107RJ1	sodium solute
FR729_RS20845	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
FR729_RS20850	ENOG41080XP	Cbs domain
FR729_RS20855	ENOG4107EJG	GntR family transcriptional regulator
FR729_RS20860	ENOG4107EJG	GntR family transcriptional regulator
FR729_RS20895	ENOG4105EY3	heparinase II III family protein
FR729_RS20900	ENOG4105EY3	heparinase II III family protein
FR729_RS20905	ENOG4105M5J	Cupin 2, conserved barrel domain protein
FR729_RS20910	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
FR729_RS20915	ENOG4108UHU	Aldolase
FR729_RS20925	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
FR729_RS20930	ENOG4105CHR	reductase
FR729_RS20935	ENOG4106E5D	Protein of unknown function (DUF461)
FR729_RS20990	ENOG4105BZU	Histidine kinase
FR729_RS20995	ENOG4105C44	Serine transporter
FR729_RS21035	ENOG4105DG7	nitrate ABC transporter
FR729_RS21040	ENOG4105D7T	ABC transporter
FR729_RS21045	ENOG4107QZF	nitrite reductase NADPH large subunit
FR729_RS21075	ENOG4105F8J	Adenylate Guanylate cyclase
FR729_RS21095	ENOG4105D9P	serine threonine protein kinase
FR729_RS21115	ENOG4106VK6	Flagellar motor protein
FR729_RS21130	ENOG4108ZF3	Phosphatase
FR729_RS21175	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
FR729_RS21200	ENOG4107RFY	SbcCD D subunit
FR729_RS21205	ENOG4105EYH	Exonuclease
FR729_RS21215	ENOG4105QNF	Outer membrane lipoprotein
FR729_RS21225	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
FR729_RS21235	ENOG4105C5W	Aldolase
FR729_RS21245	ENOG4107R4Q	Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone (By similarity)
FR729_RS21250	ENOG4105EV2	VWA domain protein interacting with AAA ATPase
FR729_RS21265	ENOG4105CC0	LysR family Transcriptional regulator
FR729_RS21270	ENOG4105CXG	d-lactate dehydrogenase
FR729_RS21285	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
FR729_RS21290	ENOG4108NVR	Methyl-accepting chemotaxis
FR729_RS21355	ENOG4105BZU	Histidine kinase
FR729_RS21360	ENOG4105NXH	GreA GreB family elongation factor
FR729_RS21365	ENOG4107QZF	nitrite reductase NADPH large subunit
FR729_RS21370	ENOG4105WZK	nitrite reductase NADPH small subunit
FR729_RS21375	ENOG4105TMB	Formate nitrite transporter
FR729_RS21380	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
FR729_RS21395	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
FR729_RS21415	ENOG4105KNA	-acetyltransferase
FR729_RS21420	ENOG4105VXR	cytoplasmic protein
FR729_RS21430	ENOG4105K63	Thioredoxin
FR729_RS21435	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
FR729_RS21455	ENOG4105EIP	mannose-6-phosphate isomerase
FR729_RS21460	ENOG4105CXY	transporter
FR729_RS21465	ENOG4105BZU	Histidine kinase
FR729_RS21470	ENOG4108KX4	response regulator
FR729_RS21475	ENOG4105CXY	transporter
FR729_RS21480	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
FR729_RS21485	ENOG4105C5Q	Transcriptional regulator
FR729_RS21490	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
FR729_RS21505	ENOG4107TIF	Phenazine biosynthesis protein, PhzF family
FR729_RS21540	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
FR729_RS21545	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
FR729_RS21550	ENOG4105UQX	Mate efflux family protein
FR729_RS21555	ENOG4108K01	transcriptional regulator
FR729_RS21560	ENOG4105CGF	Aromatic amino acid aminotransferase
FR729_RS21565	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
FR729_RS21575	ENOG4105WXI	Bacterial OB fold (BOF) protein
FR729_RS21580	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
FR729_RS21585	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
FR729_RS21590	ENOG4105E0C	molybdate abc transporter
FR729_RS21595	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
FR729_RS21625	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
FR729_RS21630	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
FR729_RS21670	ENOG4105EJC	lysr family transcriptional regulator
FR729_RS21745	ENOG4108ZJT	translation initiation factor, Sui1
FR729_RS21755	ENOG4105CPF	Cell wall formation (By similarity)
FR729_RS21765	ENOG4105CD5	CoA-binding domain protein
FR729_RS21770	ENOG4105CWB	LysR family transcriptional Regulator
FR729_RS21780	ENOG4105CMR	udp-glucose 4-epimerase
FR729_RS21785	ENOG4105BZU	Histidine kinase
FR729_RS21790	ENOG4105E7W	lamb ycsf family protein
FR729_RS21795	ENOG4105P4J	Allophanate hydrolase, subunit 1
FR729_RS21800	ENOG4107R7A	Allophanate hydrolase subunit 2
FR729_RS21810	ENOG4105CV6	ABC transporter, permease
FR729_RS21815	ENOG4108I0Y	(ABC) transporter
FR729_RS21825	ENOG4105RKW	reductase (By
FR729_RS21830	ENOG4105BZU	Histidine kinase
FR729_RS21840	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
FR729_RS21865	ENOG4105KNR	Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity)
FR729_RS21875	ENOG4105KA0	thioesterase Superfamily protein
FR729_RS21890	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
FR729_RS21895	ENOG4108M0H	Extracellular lipase
FR729_RS21915	ENOG4105DU1	integral membrane protein, terc
FR729_RS21920	ENOG4105CGH	5'-nucleotidase
FR729_RS21925	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
FR729_RS21930	ENOG4108UQ5	membrane protein YcdZ
FR729_RS21935	ENOG4105DUM	transcriptional regulator, lysR family
FR729_RS21940	ENOG4105TMB	Formate nitrite transporter
FR729_RS21945	ENOG4108YYC	ycei family
FR729_RS21950	ENOG4105DS1	cytochrome b561
FR729_RS21970	ENOG4105C1J	atp-dependent rna helicase
FR729_RS21975	ENOG4108ZYK	Acyl carrier protein phosphodiesterase
FR729_RS21985	ENOG4108N3W	hemolysin secretion protein
FR729_RS21990	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
FR729_RS22005	ENOG4107RE1	Inosine-guanosine kinase
FR729_RS22010	ENOG4105CKU	formyltetrahydrofolate synthetase
FR729_RS22015	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
FR729_RS22025	ENOG4105CF7	AraC family transcriptional regulator
FR729_RS22030	ENOG4108I6A	alcohol dehydrogenase
FR729_RS22040	ENOG4105CDA	abc transporter atp-binding protein
FR729_RS22045	ENOG4105E5Q	amino acid AbC transporter
FR729_RS22050	ENOG4106TNF	Periplasmic binding protein
FR729_RS22055	ENOG4105DRP	amino acid AbC transporter
FR729_RS22060	ENOG4108NJZ	Sensory box GGDEF EAL domain protein
FR729_RS22075	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
FR729_RS22080	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
FR729_RS22085	ENOG4105DE4	1-phosphofructokinase
FR729_RS22090	ENOG4105DM4	PTS System
FR729_RS22120	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
FR729_RS22130	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
FR729_RS22135	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
FR729_RS22140	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FR729_RS22145	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
FR729_RS22150	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
FR729_RS22155	ENOG4105EJC	lysr family transcriptional regulator
FR729_RS22160	ENOG4108IPJ	Membrane
FR729_RS22165	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
FR729_RS22190	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
FR729_RS22220	ENOG4105HDD	phospholipase
FR729_RS22235	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
FR729_RS22270	ENOG4105CJW	magnesium transporter
FR729_RS22290	ENOG4108UYE	Lactoylglutathione lyase
FR729_RS22295	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
FR729_RS22320	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
FR729_RS22335	ENOG4107RGH	Aldehyde dehydrogenase
FR729_RS22350	ENOG4108I0N	Transporter, RarD family, DMT superfamily protein
FR729_RS22375	ENOG4105FR1	rard protein
FR729_RS22385	ENOG4108VAU	general secretion pathway protein G
FR729_RS22390	ENOG4107R88	Chemotaxis protein (CheV)
FR729_RS22395	ENOG4108WQH	regulatoR
FR729_RS22405	ENOG4105BZU	Histidine kinase
FR729_RS22410	ENOG4105WH1	Two component transcriptional regulator luxr family
FR729_RS22415	ENOG4105BZU	Histidine kinase
FR729_RS22420	ENOG4105BZU	Histidine kinase
FR729_RS22425	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
FR729_RS22430	ENOG4107KBT	8-Amino-7-oxononanoate synthase
FR729_RS22435	ENOG4108MGY	Histidine kinase
FR729_RS22455	ENOG4105CEE	C4-dicarboxylate transporter
FR729_RS22470	ENOG4105F2V	VRR-NUC domain-containing protein
FR729_RS22480	ENOG4108YDI	single-species biofilm formation on inanimate substrate
FR729_RS22485	ENOG4107TE5	Lipid kinase
FR729_RS22490	ENOG41064T2	transcriptional regulator, lysR family
FR729_RS22495	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
FR729_RS22525	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
FR729_RS22530	ENOG4105C4X	radical SAM domain protein
FR729_RS22535	ENOG41061MV	Arylsulfatase
FR729_RS22545	ENOG4105ENH	Sulfatase
FR729_RS22550	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
FR729_RS22565	ENOG4105BZU	Histidine kinase
FR729_RS22570	ENOG4108SV3	Tmao reductase system periplasmic protein tort
FR729_RS22575	ENOG4108Z5K	methylglyoxal synthase
FR729_RS22580	ENOG41088T4	Helicase IV
FR729_RS22585	ENOG4105EM2	membrane
FR729_RS22625	ENOG4108Z6Z	Transcriptional regulator
FR729_RS22630	ENOG4108IPW	abc transporter atp-binding protein
FR729_RS22635	ENOG4105CM4	permease protein
FR729_RS22640	ENOG4105DHS	permease protein
FR729_RS22655	ENOG4108I5U	Uridine phosphorylase
FR729_RS22660	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
FR729_RS22665	ENOG4105ETE	Transcriptional regulator (LacI family
FR729_RS22670	ENOG4108RVA	ribokinase
FR729_RS22675	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
FR729_RS22680	ENOG4105CNN	ABC, transporter
FR729_RS22685	ENOG4105C2J	ABC transporter
FR729_RS22690	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
FR729_RS22695	ENOG4108K0B	C-di-gmp phosphodiesterase
FR729_RS22750	ENOG4105D82	Glutamate dehydrogenase
FR729_RS22760	ENOG4105BZU	Histidine kinase
FR729_RS22765	ENOG4105CA0	peroxidase
FR729_RS22775	ENOG4107QX8	SPFH domain, Band 7 family protein
FR729_RS22785	ENOG4108RCM	Nitroreductase
FR729_RS22790	ENOG4108IJ7	Glycine betaine
FR729_RS22795	ENOG4108HQS	Glycine betaine
FR729_RS22805	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
FR729_RS22810	ENOG4105C26	Dehydrogenase
FR729_RS22815	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
FR729_RS22830	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
FR729_RS22840	ENOG4105E39	Enoyl-CoA hydratase
FR729_RS22845	ENOG4105C1G	acyl-Coa dehydrogenase
FR729_RS22850	ENOG4105C26	Dehydrogenase
FR729_RS22855	ENOG4105CHU	acetyl-coa acetyltransferase
FR729_RS22865	ENOG4105C1G	acyl-Coa dehydrogenase
FR729_RS22870	ENOG4107QX3	carboxylase
FR729_RS22875	ENOG4108IPT	Naphthoate synthase
FR729_RS22885	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
FR729_RS22895	ENOG4105EGS	Mechanosensitive ion channel
FR729_RS22900	ENOG4108UW5	maltose o-acetyltransferase
FR729_RS22905	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
FR729_RS22910	ENOG4105C4M	(Ubiquinol oxidase) subunit I
FR729_RS22915	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
FR729_RS22930	ENOG4107YBY	Hydrolase
FR729_RS22940	ENOG4107FQX	Alpha-acetolactate decarboxylase
FR729_RS22945	ENOG4105C7K	acetolactate synthase
FR729_RS22950	ENOG4105CHR	reductase
FR729_RS22955	ENOG4105FQ6	thiopurine methyltransferase
FR729_RS22960	ENOG4105DZS	Phenylacetate-CoA ligase
FR729_RS22965	ENOG4108IV0	ABC, transporter
FR729_RS22985	ENOG4108IQE	Amp-dependent synthetase and ligase
FR729_RS22990	ENOG4105C0Z	ABC transporter
FR729_RS22995	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
FR729_RS23000	ENOG4105BZJ	Electron transfer flavoprotein
FR729_RS23005	ENOG4105C10	Electron transfer flavoprotein
FR729_RS23010	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
FR729_RS23015	ENOG4105CI1	PTS System
FR729_RS23020	ENOG4105F8D	glycoside hydrolase family 4
FR729_RS23025	ENOG4105FDP	GntR family transcriptional regulator
FR729_RS23030	ENOG4105KJM	monovalent cation h antiporter subunit g
FR729_RS23035	ENOG41080TA	Multiple resistance and ph regulation protein f
FR729_RS23040	ENOG4105SC1	monovalent cation H antiporter subunit E
FR729_RS23045	ENOG4108JPZ	Monovalent cation H antiporter subunit D
FR729_RS23050	ENOG4108ZE9	Monovalent cation H antiporter subunit C
FR729_RS23055	ENOG4105D65	subunit l
FR729_RS23065	ENOG4105Q9Y	Universal stress protein
FR729_RS23070	ENOG4105EMU	Dehydrogenase
FR729_RS23075	ENOG4105HEI	LysR family (Transcriptional regulator
FR729_RS23085	ENOG4105C2C	drug resistance transporter, Bcr CflA
FR729_RS23150	ENOG4105EW9	transcriptional regulator AsnC family
FR729_RS23185	ENOG4105D9P	serine threonine protein kinase
FR729_RS23210	ENOG4105CS6	Rhs element vgr protein
FR729_RS23215	ENOG4108WC9	type VI secretion system effector, hcp1 family
FR729_RS23220	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
FR729_RS23225	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FR729_RS23250	ENOG4105DR5	peptidase
FR729_RS23265	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
FR729_RS23280	ENOG4105C3I	Nad-dependent epimerase dehydratase
FR729_RS23310	ENOG4107QHE	Choloylglycine hydrolase
FR729_RS23315	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
FR729_RS23320	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
FR729_RS23330	ENOG4108UNF	response regulator
FR729_RS23335	ENOG4107RGM	aldo keto reductase
FR729_RS23350	ENOG4105CMQ	Chloride channel
FR729_RS23360	ENOG4105EUJ	GTP cyclohydrolase i
FR729_RS23365	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
FR729_RS23370	ENOG4105D06	uba thif-type nad fad binding protein
FR729_RS23390	ENOG4105KHC	sulfurtransferase
FR729_RS23400	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
FR729_RS23405	ENOG4105CV1	Transketolase (EC 2.2.1.1)
FR729_RS23410	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
FR729_RS23415	ENOG4105DXI	Major Facilitator superfamily
FR729_RS23420	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
FR729_RS23425	ENOG4105UYK	outer membrane protein a
FR729_RS23430	ENOG4107VXZ	Hydrolase
FR729_RS23435	ENOG4108YZN	class I peptide chain release factor
FR729_RS23440	ENOG4108N3W	hemolysin secretion protein
FR729_RS23455	ENOG4107YWA	deoxycytidylate deaminase
FR729_RS23460	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
FR729_RS23475	ENOG4105WH1	Two component transcriptional regulator luxr family
FR729_RS23480	ENOG4105BZU	Histidine kinase
FR729_RS23495	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
FR729_RS23515	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
FR729_RS23525	ENOG4105CHU	acetyl-coa acetyltransferase
FR729_RS23545	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
FR729_RS23550	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
FR729_RS23580	ENOG4105EW9	transcriptional regulator AsnC family
FR729_RS23600	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
FR729_RS23605	ENOG4108US0	Transcription regulator that can specifically activate or repress expression of target genes (By similarity)
FR729_RS23610	ENOG4105BZU	Histidine kinase
FR729_RS23615	ENOG4108QGH	periplasmic
FR729_RS23620	ENOG41082IR	Excinuclease ABC C subunit domain protein
FR729_RS23625	ENOG4108YXG	UPF0502 protein
FR729_RS23635	ENOG41090HJ	UPF0265 protein
FR729_RS23645	ENOG4105BZU	Histidine kinase
FR729_RS23670	ENOG4105DUM	transcriptional regulator, lysR family
FR729_RS23680	ENOG4105DVH	amino acid
FR729_RS23695	ENOG4105E0F	Histidine kinase
FR729_RS23700	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
FR729_RS23725	ENOG4105EFX	secretion protein, HlyD family
FR729_RS23730	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
FR729_RS23735	ENOG4105CJW	magnesium transporter
FR729_RS23740	ENOG4105DQW	permease for cytosine purines, uracil, thiamine, allantoin
FR729_RS23745	ENOG4105DZC	cytosine deaminase
FR729_RS23750	ENOG4105EST	Metal Dependent Phosphohydrolase
FR729_RS23760	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
FR729_RS23770	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
FR729_RS23790	ENOG4108Z33	Thiol disulfide Interchange Protein
FR729_RS23805	ENOG4107EXC	regulatoR
FR729_RS23810	ENOG4105E0F	Histidine kinase
FR729_RS23820	ENOG41080IJ	Diacylglycerol kinase
FR729_RS23825	ENOG4105DIJ	Phosphoethanolamine transferase
FR729_RS23830	ENOG4105EP9	oxidoreductase
FR729_RS23845	ENOG4108NRW	Phospholipase, patatin family
FR729_RS23850	ENOG4105EUB	pirin domain protein
FR729_RS23855	ENOG4105VEQ	Cold shock protein
FR729_RS23870	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
FR729_RS23875	ENOG4105EHV	domain protein
FR729_RS23885	ENOG4105DZ1	carboxypeptidase
FR729_RS23890	ENOG4105CYM	Glutathione S-transferase
FR729_RS23900	ENOG4108HKT	sucrose-6-phosphate hydrolase
FR729_RS23905	ENOG4105D7K	pfkb domain protein
FR729_RS23930	ENOG4105CHR	reductase
FR729_RS23945	ENOG4108P3C	
FR729_RS23965	ENOG4105HEI	LysR family (Transcriptional regulator
FR729_RS23970	ENOG410874W	AraC family transcriptional regulator
FR729_RS23975	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
FR729_RS23995	ENOG4105C1J	atp-dependent rna helicase
FR729_RS24005	ENOG4107RSM	transcriptional regulator