locus-tag	class	description
AL541_RS00030	COG1494	fructose-1,6-bisphosphatase
AL541_RS00040	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AL541_RS00045	COG1575	Belongs to the MenA family. Type 1 subfamily
AL541_RS00050	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AL541_RS00055	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AL541_RS00065	COG1609	Transcriptional regulator
AL541_RS00070	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AL541_RS00080	COG0254	rRNA binding
AL541_RS00090	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AL541_RS00095	COG0088	Forms part of the polypeptide exit tunnel
AL541_RS00105	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AL541_RS00110	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AL541_RS00115	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AL541_RS00120	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AL541_RS00130	COG0255	Belongs to the universal ribosomal protein uL29 family
AL541_RS00135	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AL541_RS00145	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AL541_RS00150	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AL541_RS00160	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AL541_RS00165	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AL541_RS00180	COG1841	ribosomal large subunit assembly
AL541_RS00185	COG0200	Binds to the 23S rRNA
AL541_RS00190	COG0201	protein transport
AL541_RS00195	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AL541_RS00200	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AL541_RS00205	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AL541_RS00215	COG0202	RNA polymerase activity
AL541_RS00220	COG0203	ribosomal protein L17
AL541_RS00230	COG0545	Peptidyl-prolyl cis-trans isomerase
AL541_RS00240	COG2153	protein acetylation
AL541_RS00245	COG0513	Belongs to the DEAD box helicase family
AL541_RS00260	COG1648	precorrin-2 dehydrogenase activity
AL541_RS00260	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AL541_RS00265	COG0175	sulfate reduction
AL541_RS00270	COG2895	sulfate adenylyltransferase (ATP) activity
AL541_RS00275	COG0471	metal ion transport
AL541_RS00275	COG3273	potassium ion transport
AL541_RS00280	COG0529	Catalyzes the synthesis of activated sulfate
AL541_RS00300	COG4181	ATPase activity
AL541_RS00315	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
AL541_RS00325	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL541_RS00330	COG0729	surface antigen
AL541_RS00335	COG2911	Protein conserved in bacteria
AL541_RS00340	COG2105	PFAM AIG2 family protein
AL541_RS00350	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AL541_RS00355	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AL541_RS00365	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AL541_RS00370	COG0163	prenyltransferase activity
AL541_RS00375	COG4143	(ABC) transporter
AL541_RS00380	COG1178	ABC-type Fe3 transport system permease component
AL541_RS00385	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
AL541_RS00390	COG0583	DNA-binding transcription factor activity
AL541_RS00395	COG1902	pentaerythritol trinitrate reductase activity
AL541_RS00415	COG2358	TRAP transporter, solute receptor (TAXI family
AL541_RS00440	COG0142	geranyltranstransferase activity
AL541_RS00445	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AL541_RS00455	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AL541_RS00460	COG2966	Psort location CytoplasmicMembrane, score
AL541_RS00470	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AL541_RS00475	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AL541_RS00480	COG2967	ApaG domain
AL541_RS00485	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AL541_RS00490	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AL541_RS00495	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL541_RS00500	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AL541_RS00505	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AL541_RS00525	COG0473	3-isopropylmalate dehydrogenase activity
AL541_RS00530	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AL541_RS00555	COG0583	DNA-binding transcription factor activity
AL541_RS00560	COG1022	Amp-dependent synthetase and ligase
AL541_RS00565	COG0028	Belongs to the TPP enzyme family
AL541_RS00570	COG0440	acetolactate synthase activity
AL541_RS00585	COG0469	pyruvate kinase activity
AL541_RS00590	COG1349	DNA-binding transcription factor activity
AL541_RS00595	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AL541_RS00605	COG2376	Dihydroxyacetone kinase
AL541_RS00610	COG1461	Dihydroxyacetone kinase
AL541_RS00625	COG3722	fumarate hydratase activity
AL541_RS00635	COG2213	PTS system mannitol-specific
AL541_RS00635	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL541_RS00710	COG3550	peptidyl-serine autophosphorylation
AL541_RS00735	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AL541_RS00745	COG3550	peptidyl-serine autophosphorylation
AL541_RS00765	COG0358	DNA primase activity
AL541_RS00770	COG1610	YqeY-like protein
AL541_RS00775	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AL541_RS00780	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AL541_RS00785	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AL541_RS00790	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AL541_RS00795	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AL541_RS00800	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AL541_RS00805	COG1968	undecaprenyl-diphosphatase activity
AL541_RS00815	COG3409	Peptidoglycan-binding domain 1 protein
AL541_RS00815	COG3267	Type II secretory pathway component ExeA
AL541_RS00825	COG0405	Gamma-glutamyltransferase
AL541_RS00830	COG4991	sh3 domain protein
AL541_RS00835	COG0306	phosphate transporter
AL541_RS00840	COG1392	Phosphate transport regulator
AL541_RS00845	COG3025	triphosphatase activity
AL541_RS00860	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AL541_RS00865	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AL541_RS00865	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AL541_RS00870	COG1538	Outer membrane efflux protein
AL541_RS00875	COG0494	nUDIX hydrolase
AL541_RS00880	COG3151	Protein conserved in bacteria
AL541_RS00890	COG3150	esterase
AL541_RS00900	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AL541_RS00905	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AL541_RS00910	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AL541_RS00915	COG3105	Protein conserved in bacteria
AL541_RS00925	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AL541_RS00940	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AL541_RS00945	COG0723	plastoquinol--plastocyanin reductase activity
AL541_RS00950	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AL541_RS00955	COG2857	Cytochrome c1
AL541_RS00960	COG0625	glutathione transferase activity
AL541_RS00965	COG2969	positive regulation of protein catabolic process
AL541_RS00970	COG2823	Periplasmic or secreted lipoprotein
AL541_RS00975	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AL541_RS00990	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AL541_RS01010	COG3116	cell division
AL541_RS01015	COG0768	penicillin binding
AL541_RS01020	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AL541_RS01025	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AL541_RS01030	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AL541_RS01035	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AL541_RS01040	COG0772	Belongs to the SEDS family
AL541_RS01055	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AL541_RS01060	COG0849	cell division
AL541_RS01065	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AL541_RS01070	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AL541_RS01080	COG0653	protein targeting
AL541_RS01085	COG0494	nUDIX hydrolase
AL541_RS01095	COG0505	Belongs to the CarA family
AL541_RS01100	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AL541_RS01115	COG0730	response to heat
AL541_RS01120	COG0583	DNA-binding transcription factor activity
AL541_RS01125	COG2860	membrane
AL541_RS01140	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AL541_RS01150	COG0493	'glutamate synthase
AL541_RS01155	COG0070	glutamate synthase
AL541_RS01155	COG0069	glutamate synthase activity
AL541_RS01155	COG0067	glutamate synthase
AL541_RS01165	COG0067	glutamate synthase
AL541_RS01165	COG0070	glutamate synthase
AL541_RS01165	COG0069	glutamate synthase activity
AL541_RS01170	COG1242	4 iron, 4 sulfur cluster binding
AL541_RS01175	COG3706	GGDEF domain
AL541_RS01175	COG5001	Diguanylate cyclase
AL541_RS01175	COG4251	negative regulation of phosphorylation
AL541_RS01175	COG2203	Gaf domain
AL541_RS01180	COG5002	protein histidine kinase activity
AL541_RS01180	COG0784	Response regulator, receiver
AL541_RS01180	COG2198	Histidine kinase
AL541_RS01190	COG0745	RESPONSE REGULATOR receiver
AL541_RS01205	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AL541_RS01225	COG0083	homoserine kinase activity
AL541_RS01230	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AL541_RS01240	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
AL541_RS01245	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AL541_RS01255	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AL541_RS01270	COG1115	amino acid carrier protein
AL541_RS01275	COG3022	response to hydroperoxide
AL541_RS01280	COG0513	Belongs to the DEAD box helicase family
AL541_RS01285	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AL541_RS01295	COG0716	FMN binding
AL541_RS01300	COG4974	Belongs to the 'phage' integrase family
AL541_RS01305	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AL541_RS01310	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AL541_RS01325	COG2204	response regulator
AL541_RS01335	COG0667	Aldo Keto reductase
AL541_RS01360	COG0730	response to heat
AL541_RS01365	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AL541_RS01370	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AL541_RS01380	COG1283	sodium-dependent phosphate transmembrane transporter activity
AL541_RS01385	COG0583	DNA-binding transcription factor activity
AL541_RS01390	COG0640	Transcriptional regulator
AL541_RS01395	COG0268	Binds directly to 16S ribosomal RNA
AL541_RS01400	COG0728	peptidoglycan biosynthetic process
AL541_RS01405	COG0196	riboflavin kinase activity
AL541_RS01420	COG1047	Peptidyl-prolyl cis-trans
AL541_RS01425	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AL541_RS01435	COG3279	Response regulator of the LytR AlgR family
AL541_RS01440	COG3275	phosphorelay sensor kinase activity
AL541_RS01445	COG1966	Carbon starvation protein
AL541_RS01465	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AL541_RS01470	COG1472	Belongs to the glycosyl hydrolase 3 family
AL541_RS01475	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AL541_RS01480	COG0287	Prephenate dehydrogenase
AL541_RS01480	COG1605	Chorismate mutase
AL541_RS01485	COG0739	heme binding
AL541_RS01495	COG0488	(ABC) transporter
AL541_RS01505	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
AL541_RS01510	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
AL541_RS01515	COG1605	Chorismate mutase
AL541_RS01515	COG0077	Prephenate dehydratase
AL541_RS01520	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AL541_RS01530	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL541_RS01535	COG0564	pseudouridine synthase activity
AL541_RS01545	COG0542	response to heat
AL541_RS01610	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL541_RS01615	COG0826	peptidase U32
AL541_RS01620	COG2974	May be involved in recombination
AL541_RS01630	COG0745	RESPONSE REGULATOR receiver
AL541_RS01635	COG5002	protein histidine kinase activity
AL541_RS01645	COG0248	Ppx GppA phosphatase
AL541_RS01650	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AL541_RS01655	COG0573	inorganic phosphate transmembrane transporter activity
AL541_RS01660	COG0581	inorganic phosphate transmembrane transporter activity
AL541_RS01665	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AL541_RS01670	COG0704	Plays a role in the regulation of phosphate uptake
AL541_RS01680	COG3142	Participates in the control of copper homeostasis
AL541_RS01685	COG0450	alkyl hydroperoxide reductase
AL541_RS01690	COG0583	DNA-binding transcription factor activity
AL541_RS01695	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AL541_RS01705	COG0517	IMP dehydrogenase activity
AL541_RS01715	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AL541_RS01725	COG1862	Preprotein translocase
AL541_RS01730	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL541_RS01735	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL541_RS01750	COG0483	inositol monophosphate 1-phosphatase activity
AL541_RS01755	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AL541_RS01765	COG1104	cysteine desulfurase activity
AL541_RS01770	COG0822	iron-sulfur transferase activity
AL541_RS01785	COG0443	Heat shock 70 kDa protein
AL541_RS01790	COG0633	Ferredoxin
AL541_RS01795	COG2975	iron-sulfur cluster assembly
AL541_RS01805	COG0105	UTP biosynthetic process
AL541_RS01820	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AL541_RS01825	COG0124	histidyl-tRNA synthetase
AL541_RS01830	COG2976	Protein conserved in bacteria
AL541_RS01835	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL541_RS01840	COG1160	GTP binding
AL541_RS01860	COG0516	GMP reductase activity
AL541_RS01860	COG0517	IMP dehydrogenase activity
AL541_RS01870	COG1757	Na H antiporter
AL541_RS01880	COG1584	GPR1 FUN34 yaaH family protein
AL541_RS01885	COG1115	amino acid carrier protein
AL541_RS01900	COG2873	o-acetylhomoserine
AL541_RS01905	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AL541_RS01925	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AL541_RS01925	COG3153	acetyltransferase
AL541_RS01930	COG0583	DNA-binding transcription factor activity
AL541_RS01955	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AL541_RS01960	COG2867	negative regulation of translational initiation
AL541_RS01965	COG2914	Belongs to the UPF0125 (RnfH) family
AL541_RS01970	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL541_RS01980	COG0497	DNA recombination
AL541_RS01990	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AL541_RS01995	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AL541_RS02000	COG1301	dicarboxylic acid transport
AL541_RS02010	COG0484	heat shock protein binding
AL541_RS02040	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AL541_RS02055	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AL541_RS02060	COG0047	phosphoribosylformylglycinamidine synthase activity
AL541_RS02060	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AL541_RS02090	COG2195	Cleaves the N-terminal amino acid of tripeptides
AL541_RS02095	COG2252	PERMEase
AL541_RS02100	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AL541_RS02105	COG1073	alpha beta
AL541_RS02115	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AL541_RS02120	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AL541_RS02125	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AL541_RS02130	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AL541_RS02130	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AL541_RS02145	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AL541_RS02155	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AL541_RS02160	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AL541_RS02165	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AL541_RS02170	COG0142	geranyltranstransferase activity
AL541_RS02175	COG1722	exodeoxyribonuclease VII activity
AL541_RS02180	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AL541_RS02190	COG0301	tRNA thio-modification
AL541_RS02190	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AL541_RS02195	COG0583	DNA-binding transcription factor activity
AL541_RS02205	COG2363	Small membrane protein
AL541_RS02215	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AL541_RS02220	COG1611	Belongs to the LOG family
AL541_RS02235	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AL541_RS02235	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AL541_RS02245	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
AL541_RS02250	COG1464	Belongs to the NlpA lipoprotein family
AL541_RS02255	COG2011	ABC-type metal ion transport system permease component
AL541_RS02260	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AL541_RS02265	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AL541_RS02275	COG1263	PTS System
AL541_RS02275	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL541_RS02280	COG0366	Alpha amylase catalytic
AL541_RS02295	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AL541_RS02300	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AL541_RS02305	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AL541_RS02310	COG0321	lipoyl(octanoyl) transferase activity
AL541_RS02320	COG1686	Belongs to the peptidase S11 family
AL541_RS02325	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AL541_RS02330	COG0772	Belongs to the SEDS family
AL541_RS02335	COG0768	penicillin binding
AL541_RS02340	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AL541_RS02345	COG0799	negative regulation of ribosome biogenesis
AL541_RS02350	COG1466	dna polymerase III delta subunit
AL541_RS02355	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
AL541_RS02360	COG0495	leucyl-tRNA aminoacylation
AL541_RS02365	COG2888	peptidyl-tyrosine sulfation
AL541_RS02370	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AL541_RS02375	COG4535	Mg2 and Co2 transporter CorC
AL541_RS02380	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AL541_RS02385	COG1702	phosphate starvation-inducible protein PhoH
AL541_RS02390	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AL541_RS02400	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL541_RS02510	COG0012	GTP binding
AL541_RS02515	COG0193	aminoacyl-tRNA hydrolase activity
AL541_RS02520	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AL541_RS02525	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AL541_RS02530	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AL541_RS02535	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AL541_RS02545	COG2890	protein-(glutamine-N5) methyltransferase activity
AL541_RS02550	COG3094	Invasion gene expression up-regulator, SirB
AL541_RS02555	COG2912	Transglutaminase-like superfamily
AL541_RS02560	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AL541_RS02565	COG0737	Belongs to the 5'-nucleotidase family
AL541_RS02570	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AL541_RS02575	COG1187	pseudouridine synthase activity
AL541_RS02580	COG2840	Smr protein MutS2
AL541_RS02620	COG2217	Heavy metal translocating P-type atpase
AL541_RS02620	COG2608	mercury ion transmembrane transporter activity
AL541_RS02635	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
AL541_RS02690	COG0784	Response regulator, receiver
AL541_RS02690	COG0835	chemotaxis
AL541_RS02695	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AL541_RS02700	COG1815	bacterial-type flagellum-dependent cell motility
AL541_RS02705	COG1558	bacterial-type flagellum-dependent cell motility
AL541_RS02715	COG1749	Flagellar hook protein flgE
AL541_RS02720	COG4787	bacterial-type flagellum-dependent cell motility
AL541_RS02730	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AL541_RS02735	COG1706	bacterial-type flagellum-dependent cell motility
AL541_RS02740	COG3951	Flagellar rod assembly protein muramidase FlgJ
AL541_RS02740	COG1705	Flagellar rod assembly protein muramidase FlgJ
AL541_RS02750	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AL541_RS02755	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AL541_RS02765	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AL541_RS02780	COG2190	(PTS) system
AL541_RS02785	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AL541_RS02790	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL541_RS02800	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AL541_RS02805	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
AL541_RS02810	COG3115	cell septum assembly
AL541_RS02815	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AL541_RS02840	COG0330	HflC and HflK could
AL541_RS02845	COG3118	belongs to the thioredoxin family
AL541_RS02855	COG0300	oxidoreductase activity
AL541_RS02860	COG1090	epimerase
AL541_RS02890	COG0622	Phosphoesterase
AL541_RS02910	COG3710	Transcriptional regulator
AL541_RS02915	COG0326	Molecular chaperone. Has ATPase activity
AL541_RS02925	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AL541_RS02930	COG3104	oligopeptide transport
AL541_RS02935	COG0250	Participates in transcription elongation, termination and antitermination
AL541_RS02940	COG0367	asparagine synthase
AL541_RS02945	COG4651	solute:proton antiporter activity
AL541_RS02945	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AL541_RS02950	COG1846	Transcriptional regulator
AL541_RS02950	COG1940	carbohydrate kinase activity
AL541_RS02955	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AL541_RS02965	COG1263	PTS System
AL541_RS02965	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL541_RS02965	COG2190	(PTS) system
AL541_RS02970	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AL541_RS02975	COG0735	belongs to the Fur family
AL541_RS02985	COG0716	FMN binding
AL541_RS02995	COG0596	Alpha beta hydrolase
AL541_RS03000	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
AL541_RS03005	COG0033	Phosphoglucomutase
AL541_RS03015	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AL541_RS03030	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AL541_RS03035	COG1053	succinate dehydrogenase
AL541_RS03040	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AL541_RS03045	COG0567	Dehydrogenase, E1 component
AL541_RS03050	COG0508	dehydrogenase complex catalyzes the overall conversion of
AL541_RS03055	COG0045	succinate-CoA ligase (ADP-forming) activity
AL541_RS03065	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AL541_RS03070	COG1121	(ABC) transporter
AL541_RS03075	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
AL541_RS03080	COG4977	sequence-specific DNA binding
AL541_RS03085	COG1918	ferrous iron import across plasma membrane
AL541_RS03110	COG0018	arginyl-trna synthetase
AL541_RS03120	COG3102	Protein conserved in bacteria
AL541_RS03125	COG0788	formyltetrahydrofolate deformylase activity
AL541_RS03130	COG1199	ATP-dependent helicase activity
AL541_RS03135	COG1214	PFAM Peptidase M22, glycoprotease
AL541_RS03145	COG3065	identical protein binding
AL541_RS03150	COG2267	carboxylic ester hydrolase activity
AL541_RS03155	COG0318	PFAM AMP-dependent synthetase and ligase
AL541_RS03160	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AL541_RS03165	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AL541_RS03170	COG2894	cell division
AL541_RS03175	COG0850	regulation of cytokinetic process
AL541_RS03180	COG3100	YcgL domain-containing protein
AL541_RS03185	COG2951	lytic endotransglycosylase activity
AL541_RS03195	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AL541_RS03200	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AL541_RS03215	COG1028	Short-chain dehydrogenase reductase Sdr
AL541_RS03225	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AL541_RS03250	COG2986	histidine ammonia-lyase
AL541_RS03255	COG1216	Glycosyl transferase, family 2
AL541_RS03260	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AL541_RS03275	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AL541_RS03280	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AL541_RS03315	COG0513	Belongs to the DEAD box helicase family
AL541_RS03320	COG0569	domain protein
AL541_RS03325	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AL541_RS03340	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AL541_RS03345	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AL541_RS03350	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AL541_RS03355	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AL541_RS03380	COG0544	peptidyl-prolyl cis-trans isomerase activity
AL541_RS03390	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AL541_RS03395	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AL541_RS03400	COG0776	regulation of translation
AL541_RS03405	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL541_RS03410	COG1555	photosystem II stabilization
AL541_RS03425	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AL541_RS03430	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AL541_RS03435	COG0436	Aminotransferase
AL541_RS03440	COG1169	isochorismate synthase
AL541_RS03455	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AL541_RS03475	COG2855	membrane
AL541_RS03480	COG0477	Major facilitator Superfamily
AL541_RS03525	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL541_RS03530	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL541_RS03545	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AL541_RS03550	COG1522	sequence-specific DNA binding
AL541_RS03560	COG1946	Acyl-CoA thioesterase
AL541_RS03565	COG3126	Type III secretion system lipoprotein chaperone (YscW)
AL541_RS03590	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AL541_RS03595	COG0516	GMP reductase activity
AL541_RS03595	COG0517	IMP dehydrogenase activity
AL541_RS03620	COG0537	adenosine 5'-monophosphoramidase activity
AL541_RS03645	COG3150	esterase
AL541_RS03650	COG1252	NADH dehydrogenase
AL541_RS03665	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AL541_RS03675	COG4591	ABC-type transport system involved in lipoprotein release permease component
AL541_RS03680	COG1136	(ABC) transporter
AL541_RS03685	COG4591	ABC-type transport system involved in lipoprotein release permease component
AL541_RS03695	COG2333	competence protein COMEC
AL541_RS03695	COG0658	competence protein
AL541_RS03705	COG1132	(ABC) transporter
AL541_RS03725	COG2719	SpoVR family
AL541_RS03730	COG2718	Belongs to the UPF0229 family
AL541_RS03735	COG2766	serine protein kinase
AL541_RS03745	COG3013	Belongs to the UPF0304 family
AL541_RS03755	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AL541_RS03765	COG1882	Formate acetyltransferase
AL541_RS03810	COG0708	Exodeoxyribonuclease III
AL541_RS03820	COG3923	Primosomal replication protein n
AL541_RS03825	COG0730	response to heat
AL541_RS03830	COG1199	ATP-dependent helicase activity
AL541_RS03835	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL541_RS03840	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
AL541_RS03845	COG1187	pseudouridine synthase activity
AL541_RS03855	COG1278	Cold shock
AL541_RS03860	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AL541_RS03865	COG0542	response to heat
AL541_RS03870	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AL541_RS03875	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AL541_RS03880	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AL541_RS03900	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AL541_RS03905	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AL541_RS03910	COG0297	glycogen (starch) synthase activity
AL541_RS03930	COG3070	regulator of competence-specific genes
AL541_RS03935	COG1609	Transcriptional regulator
AL541_RS03940	COG3381	protein complex oligomerization
AL541_RS03945	COG0745	RESPONSE REGULATOR receiver
AL541_RS03950	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AL541_RS03955	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AL541_RS03960	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
AL541_RS03965	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
AL541_RS03970	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AL541_RS03990	COG4067	protein conserved in archaea
AL541_RS03990	COG0189	ligase activity
AL541_RS04000	COG0500	methyltransferase
AL541_RS04010	COG1801	Protein of unknown function DUF72
AL541_RS04020	COG0217	transcriptional regulatory protein
AL541_RS04025	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AL541_RS04030	COG0632	four-way junction helicase activity
AL541_RS04035	COG2255	four-way junction helicase activity
AL541_RS04040	COG1271	oxidase subunit
AL541_RS04045	COG1294	oxidase, subunit
AL541_RS04050	COG4890	Cyd operon protein YbgT
AL541_RS04060	COG0824	Thioesterase
AL541_RS04065	COG0811	peptide transport
AL541_RS04080	COG0823	Involved in the tonB-independent uptake of proteins
AL541_RS04085	COG2885	chlorophyll binding
AL541_RS04090	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AL541_RS04095	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AL541_RS04105	COG3766	membrane
AL541_RS04115	COG0754	glutathionylspermidine amidase activity
AL541_RS04125	COG0784	Response regulator, receiver
AL541_RS04125	COG5002	protein histidine kinase activity
AL541_RS04140	COG1294	oxidase, subunit
AL541_RS04145	COG1271	oxidase subunit
AL541_RS04165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL541_RS04170	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL541_RS04195	COG3568	Endonuclease Exonuclease Phosphatase
AL541_RS04220	COG0583	DNA-binding transcription factor activity
AL541_RS04230	COG0686	Belongs to the AlaDH PNT family
AL541_RS04240	COG1674	ftsk spoiiie
AL541_RS04250	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AL541_RS04270	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AL541_RS04295	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AL541_RS04315	COG0300	oxidoreductase activity
AL541_RS04330	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AL541_RS04340	COG2268	Band 7 protein
AL541_RS04350	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AL541_RS04355	COG2915	High frequency lysogenization protein hflD homolog
AL541_RS04370	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL541_RS04380	COG1757	Na H antiporter
AL541_RS04390	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AL541_RS04400	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AL541_RS04400	COG0131	Imidazoleglycerol-phosphate dehydratase
AL541_RS04405	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AL541_RS04410	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AL541_RS04420	COG0140	phosphoribosyl-ATP diphosphatase activity
AL541_RS04420	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AL541_RS04425	COG3012	SEC-C Motif Domain Protein
AL541_RS04430	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AL541_RS04435	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AL541_RS04440	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AL541_RS04445	COG0215	cysteine-tRNA ligase activity
AL541_RS04450	COG1435	thymidine kinase activity
AL541_RS04455	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AL541_RS04480	COG2116	formate transmembrane transporter activity
AL541_RS04490	COG0390	transport system, permease component
AL541_RS04495	COG4459	periplasmic nitrate reductase
AL541_RS04500	COG3005	denitrification pathway
AL541_RS04505	COG0243	molybdopterin cofactor binding
AL541_RS04520	COG1227	inorganic diphosphatase activity
AL541_RS04530	COG4172	Belongs to the ABC transporter superfamily
AL541_RS04540	COG4171	peptide transport system, permease
AL541_RS04555	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AL541_RS04560	COG1842	Phage shock protein A
AL541_RS04570	COG1983	PspC domain protein
AL541_RS04590	COG2818	Glycosylase
AL541_RS04595	COG5380	lipid catabolic process
AL541_RS04600	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AL541_RS04605	COG0626	cystathionine gamma-synthase activity
AL541_RS04615	COG0733	neurotransmitter:sodium symporter activity
AL541_RS04620	COG0564	pseudouridine synthase activity
AL541_RS04630	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL541_RS04635	COG1151	hydroxylamine reductase activity
AL541_RS04640	COG3604	Transcriptional regulator
AL541_RS04655	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AL541_RS04660	COG4136	ATPase activity
AL541_RS04665	COG4135	transport system, permease component
AL541_RS04670	COG4134	Bacterial extracellular solute-binding protein
AL541_RS04680	COG3313	Fe-S protein
AL541_RS04705	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AL541_RS04725	COG1061	Type III restriction enzyme res subunit
AL541_RS04730	COG1187	pseudouridine synthase activity
AL541_RS04740	COG2814	Major facilitator Superfamily
AL541_RS04750	COG0702	epimerase
AL541_RS04755	COG0534	Mate efflux family protein
AL541_RS04775	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AL541_RS04790	COG1960	acyl-CoA dehydrogenase activity
AL541_RS04795	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AL541_RS04800	COG3273	potassium ion transport
AL541_RS04800	COG2985	domain, Protein
AL541_RS04805	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AL541_RS04815	COG1737	Transcriptional regulator
AL541_RS04820	COG0076	glutamate decarboxylase activity
AL541_RS04830	COG2431	L-lysine efflux transmembrane transporter activity
AL541_RS04850	COG3070	regulator of competence-specific genes
AL541_RS04865	COG4191	Histidine kinase
AL541_RS04865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL541_RS04875	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AL541_RS04885	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AL541_RS04890	COG4988	ABC transporter
AL541_RS04895	COG0492	ferredoxin-NADP+ reductase activity
AL541_RS04920	COG0471	metal ion transport
AL541_RS04925	COG2949	membrane
AL541_RS04930	COG0281	malic enzyme
AL541_RS04935	COG1643	Atp-dependent helicase
AL541_RS04955	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AL541_RS04990	COG0247	lactate metabolic process
AL541_RS04990	COG0277	FAD linked oxidase domain protein
AL541_RS05005	COG2986	histidine ammonia-lyase
AL541_RS05010	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AL541_RS05015	COG0010	Belongs to the arginase family
AL541_RS05020	COG1228	amidohydrolase
AL541_RS05040	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AL541_RS05050	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AL541_RS05060	COG0393	Putative heavy-metal-binding
AL541_RS05095	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AL541_RS05100	COG0072	phenylalanine-tRNA ligase activity
AL541_RS05100	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL541_RS05110	COG0776	regulation of translation
AL541_RS05120	COG0500	methyltransferase
AL541_RS05125	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AL541_RS05130	COG0295	cytidine deaminase activity
AL541_RS05135	COG1346	cytolysis
AL541_RS05140	COG1380	Effector of murein hydrolase LrgA
AL541_RS05145	COG2925	Exonuclease
AL541_RS05150	COG1823	symporter activity
AL541_RS05155	COG0702	epimerase
AL541_RS05160	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AL541_RS05165	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AL541_RS05185	COG2988	succinylglutamate desuccinylase activity
AL541_RS05190	COG4139	cobalamin transport
AL541_RS05195	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
AL541_RS05215	COG0583	DNA-binding transcription factor activity
AL541_RS05225	COG1451	nucleotide metabolic process
AL541_RS05230	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
AL541_RS05260	COG3938	Belongs to the proline racemase family
AL541_RS05275	COG2423	ornithine cyclodeaminase activity
AL541_RS05280	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL541_RS05285	COG3842	ATPase activity
AL541_RS05295	COG1177	transmembrane transport
AL541_RS05305	COG3291	Pkd domain containing protein
AL541_RS05325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL541_RS05330	COG0601	transmembrane transport
AL541_RS05340	COG2195	Cleaves the N-terminal amino acid of tripeptides
AL541_RS05350	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AL541_RS05360	COG0625	glutathione transferase activity
AL541_RS05520	COG1742	UPF0060 membrane protein
AL541_RS05535	COG1757	Na H antiporter
AL541_RS05540	COG0174	glutamine synthetase
AL541_RS05550	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AL541_RS05555	COG1917	Cupin 2, conserved barrel domain protein
AL541_RS05555	COG1396	sequence-specific DNA binding
AL541_RS05560	COG1012	belongs to the aldehyde dehydrogenase family
AL541_RS05565	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL541_RS05575	COG2957	Belongs to the agmatine deiminase family
AL541_RS05580	COG1012	belongs to the aldehyde dehydrogenase family
AL541_RS05585	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AL541_RS05590	COG2200	EAL domain
AL541_RS05600	COG1846	Transcriptional regulator
AL541_RS05605	COG2315	Protein conserved in bacteria
AL541_RS05645	COG3063	Type IV pilus biogenesis stability protein PilW
AL541_RS05650	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
AL541_RS05665	COG1560	Kdo2-lipid A biosynthetic process
AL541_RS05670	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AL541_RS05705	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AL541_RS05745	COG1160	GTP binding
AL541_RS05750	COG1160	GTP binding
AL541_RS05760	COG2916	Histone family protein nucleoid-structuring protein H-NS
AL541_RS05800	COG1479	Protein of unknown function DUF262
AL541_RS05840	COG2199	diguanylate cyclase activity
AL541_RS05885	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AL541_RS05890	COG1280	lysine exporter protein (LysE YggA)
AL541_RS05900	COG1115	amino acid carrier protein
AL541_RS05925	COG1368	sulfuric ester hydrolase activity
AL541_RS05930	COG2113	Glycine betaine
AL541_RS05935	COG4176	ABC-type proline glycine betaine transport system permease component
AL541_RS05940	COG4175	Glycine betaine
AL541_RS05955	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AL541_RS05960	COG0456	acetyltransferase
AL541_RS05965	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AL541_RS05970	COG0662	Cupin 2, conserved barrel domain protein
AL541_RS05975	COG0527	aspartate kinase activity
AL541_RS05980	COG3119	arylsulfatase activity
AL541_RS05995	COG0641	radical SAM
AL541_RS06010	COG3119	arylsulfatase activity
AL541_RS06035	COG1538	Outer membrane efflux protein
AL541_RS06050	COG1349	DNA-binding transcription factor activity
AL541_RS06055	COG0673	inositol 2-dehydrogenase activity
AL541_RS06060	COG4702	Belongs to the UPF0303 family
AL541_RS06085	COG0471	metal ion transport
AL541_RS06100	COG5001	Diguanylate cyclase
AL541_RS06100	COG3300	MHYT domain
AL541_RS06115	COG1328	CTP reductase activity
AL541_RS06120	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AL541_RS06130	COG0861	Integral membrane protein TerC family
AL541_RS06140	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AL541_RS06150	COG0814	amino acid
AL541_RS06165	COG1120	ATPase activity
AL541_RS06170	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AL541_RS06180	COG4774	siderophore transport
AL541_RS06190	COG1132	(ABC) transporter
AL541_RS06195	COG1132	(ABC) transporter
AL541_RS06210	COG0583	DNA-binding transcription factor activity
AL541_RS06235	COG0443	Heat shock 70 kDa protein
AL541_RS06240	COG0443	Heat shock 70 kDa protein
AL541_RS06285	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AL541_RS06290	COG1643	Atp-dependent helicase
AL541_RS06305	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AL541_RS06315	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AL541_RS06320	COG1215	transferase activity, transferring glycosyl groups
AL541_RS06325	COG0438	transferase activity, transferring glycosyl groups
AL541_RS06355	COG0438	transferase activity, transferring glycosyl groups
AL541_RS06365	COG2204	response regulator
AL541_RS06395	COG1793	dna ligase
AL541_RS06405	COG0534	Mate efflux family protein
AL541_RS06410	COG0307	riboflavin synthase, alpha
AL541_RS06420	COG3001	Fructosamine kinase
AL541_RS06430	COG3706	GGDEF domain
AL541_RS06440	COG0791	NLP P60 protein
AL541_RS06470	COG3148	PFAM DTW domain containing protein
AL541_RS06475	COG1940	carbohydrate kinase activity
AL541_RS06485	COG0303	'Molybdopterin
AL541_RS06490	COG0746	molybdenum cofactor guanylyltransferase activity
AL541_RS06495	COG3842	ATPase activity
AL541_RS06510	COG2204	response regulator
AL541_RS06515	COG4191	Histidine kinase
AL541_RS06525	COG0488	(ABC) transporter
AL541_RS06530	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AL541_RS06550	COG3381	protein complex oligomerization
AL541_RS06560	COG0243	molybdopterin cofactor binding
AL541_RS06560	COG3383	formate dehydrogenase (NAD+) activity
AL541_RS06565	COG0437	4 iron, 4 sulfur cluster binding
AL541_RS06715	COG0004	ammonium transporteR
AL541_RS06720	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AL541_RS06725	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AL541_RS06735	COG1177	transmembrane transport
AL541_RS06745	COG3842	ATPase activity
AL541_RS06770	COG0589	response to stress
AL541_RS06775	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL541_RS06790	COG2217	Heavy metal translocating P-type atpase
AL541_RS06800	COG2010	Cytochrome c
AL541_RS06815	COG3278	Belongs to the heme-copper respiratory oxidase family
AL541_RS06830	COG2205	protein histidine kinase activity
AL541_RS06830	COG0784	Response regulator, receiver
AL541_RS06855	COG3120	sequence-specific DNA binding
AL541_RS06860	COG1067	ATP-dependent peptidase activity
AL541_RS06865	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AL541_RS06880	COG0488	(ABC) transporter
AL541_RS06890	COG0116	Belongs to the methyltransferase superfamily
AL541_RS06890	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AL541_RS06900	COG0167	dihydroorotate dehydrogenase activity
AL541_RS06905	COG2902	Dehydrogenase
AL541_RS06915	COG0308	aminopeptidase N
AL541_RS06930	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
AL541_RS06935	COG1956	GAF domain-containing protein
AL541_RS06940	COG1132	(ABC) transporter
AL541_RS06945	COG2995	paraquat-inducible protein a
AL541_RS06950	COG3008	intermembrane lipid transfer
AL541_RS06975	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AL541_RS06980	COG1666	GTP binding
AL541_RS06995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL541_RS07000	COG4597	amino acid ABC transporter
AL541_RS07005	COG0765	amino acid transport
AL541_RS07010	COG1126	abc transporter atp-binding protein
AL541_RS07015	COG0670	Belongs to the BI1 family
AL541_RS07025	COG2920	part of a sulfur-relay system
AL541_RS07030	COG1254	Belongs to the acylphosphatase family
AL541_RS07055	COG2885	chlorophyll binding
AL541_RS07095	COG1414	Transcriptional regulator
AL541_RS07105	COG0656	L-ascorbic acid biosynthetic process
AL541_RS07110	COG0583	DNA-binding transcription factor activity
AL541_RS07120	COG0583	DNA-binding transcription factor activity
AL541_RS07125	COG2814	Major facilitator Superfamily
AL541_RS07145	COG1335	isochorismatase
AL541_RS07150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL541_RS07165	COG1410	methionine synthase
AL541_RS07165	COG0646	methionine synthase
AL541_RS07170	COG1126	abc transporter atp-binding protein
AL541_RS07175	COG0765	amino acid transport
AL541_RS07180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL541_RS07195	COG0583	DNA-binding transcription factor activity
AL541_RS07210	COG0583	DNA-binding transcription factor activity
AL541_RS07220	COG0583	DNA-binding transcription factor activity
AL541_RS07235	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AL541_RS07240	COG0602	queuosine metabolic process
AL541_RS07245	COG0561	phosphatase activity
AL541_RS07270	COG2828	Protein conserved in bacteria
AL541_RS07280	COG0372	Belongs to the citrate synthase family
AL541_RS07285	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AL541_RS07320	COG0730	response to heat
AL541_RS07325	COG2358	TRAP transporter, solute receptor (TAXI family
AL541_RS07345	COG0457	Tetratricopeptide repeat
AL541_RS07415	COG4790	Type iii secretion
AL541_RS07420	COG4794	Type iii secretion
AL541_RS07425	COG4791	protein targeting
AL541_RS07430	COG4792	protein secretion
AL541_RS07435	COG2207	Transcriptional regulator
AL541_RS07465	COG3177	Filamentation induced by cAMP protein fic
AL541_RS07485	COG4669	(LipO)protein
AL541_RS07555	COG1012	belongs to the aldehyde dehydrogenase family
AL541_RS07560	COG3284	Transcriptional regulator
AL541_RS07575	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AL541_RS07580	COG0363	glucosamine-6-phosphate deaminase activity
AL541_RS07585	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AL541_RS07590	COG2207	Transcriptional regulator
AL541_RS07600	COG4565	transcriptional regulatory protein
AL541_RS07605	COG3290	protein histidine kinase activity
AL541_RS07620	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL541_RS07650	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AL541_RS07660	COG2985	domain, Protein
AL541_RS07685	COG2272	Belongs to the type-B carboxylesterase lipase family
AL541_RS07690	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AL541_RS07695	COG0729	surface antigen
AL541_RS07705	COG1280	lysine exporter protein (LysE YggA)
AL541_RS07710	COG1280	lysine exporter protein (LysE YggA)
AL541_RS07715	COG5507	3-demethylubiquinone-9 3-methyltransferase
AL541_RS07735	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AL541_RS07740	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL541_RS07745	COG0110	maltose O-acetyltransferase activity
AL541_RS07855	COG2824	Alkylphosphonate utilization operon protein PhnA
AL541_RS07950	COG2801	Transposase and inactivated derivatives
AL541_RS08340	COG1335	isochorismatase
AL541_RS08470	COG1280	lysine exporter protein (LysE YggA)
AL541_RS08540	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AL541_RS08635	COG2852	Protein conserved in bacteria
AL541_RS08725	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AL541_RS08810	COG0791	NLP P60 protein
AL541_RS08840	COG2026	Addiction module toxin, RelE StbE family
AL541_RS08900	COG2264	protein methyltransferase activity
AL541_RS08960	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AL541_RS08965	COG1028	Short-chain dehydrogenase reductase Sdr
AL541_RS08970	COG1169	isochorismate synthase
AL541_RS08975	COG1021	2,3-dihydroxybenzoate-AMP ligase
AL541_RS08980	COG1535	isochorismatase
AL541_RS08980	COG3433	isochorismatase activity
AL541_RS08985	COG4592	Periplasmic binding protein
AL541_RS08995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL541_RS09000	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL541_RS09005	COG1120	ATPase activity
AL541_RS09020	COG2382	esterase
AL541_RS09025	COG4774	siderophore transport
AL541_RS09025	COG1629	transport
AL541_RS09045	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL541_RS09060	COG0653	protein targeting
AL541_RS09155	COG1335	isochorismatase
AL541_RS09390	COG0653	protein targeting
AL541_RS09545	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL541_RS09555	COG3768	UPF0283 membrane protein
AL541_RS09560	COG3106	COG3106 Predicted ATPase
AL541_RS09580	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AL541_RS09585	COG0784	Response regulator, receiver
AL541_RS09585	COG2205	protein histidine kinase activity
AL541_RS09595	COG0494	nUDIX hydrolase
AL541_RS09600	COG0814	amino acid
AL541_RS09605	COG1760	l-serine dehydratase
AL541_RS09610	COG2200	EAL domain
AL541_RS09620	COG0720	synthase
AL541_RS09625	COG0840	transmembrane signaling receptor activity
AL541_RS09630	COG0017	Asparaginyl-tRNA synthetase
AL541_RS09640	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL541_RS09655	COG1448	Aminotransferase
AL541_RS09675	COG0840	transmembrane signaling receptor activity
AL541_RS09680	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AL541_RS09710	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AL541_RS09725	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AL541_RS09730	COG3108	Peptidase M15
AL541_RS09735	COG2989	Protein conserved in bacteria
AL541_RS09760	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AL541_RS09770	COG3088	subunit of a heme lyase
AL541_RS09770	COG4235	cytochrome complex assembly
AL541_RS09780	COG1138	Cytochrome C-type biogenesis protein
AL541_RS09785	COG3301	Polysulphide reductase, NrfD
AL541_RS09790	COG0437	4 iron, 4 sulfur cluster binding
AL541_RS09800	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
AL541_RS09820	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AL541_RS09830	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AL541_RS09860	COG0019	diaminopimelate decarboxylase activity
AL541_RS09900	COG0322	excinuclease ABC activity
AL541_RS09905	COG2197	response regulator
AL541_RS09910	COG0417	DNA replication proofreading
AL541_RS09930	COG1187	pseudouridine synthase activity
AL541_RS09940	COG0009	L-threonylcarbamoyladenylate synthase
AL541_RS09945	COG0613	PHP domain protein
AL541_RS09955	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AL541_RS09960	COG0512	Glutamine amidotransferase of anthranilate synthase
AL541_RS09970	COG0135	phosphoribosylanthranilate isomerase activity
AL541_RS09970	COG0134	indole-3-glycerol-phosphate synthase activity
AL541_RS09980	COG0159	tryptophan synthase activity
AL541_RS09985	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL541_RS09990	COG0318	PFAM AMP-dependent synthetase and ligase
AL541_RS10000	COG1301	dicarboxylic acid transport
AL541_RS10020	COG2917	probably involved in intracellular septation
AL541_RS10030	COG2350	Protein conserved in bacteria
AL541_RS10040	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AL541_RS10045	COG0583	DNA-binding transcription factor activity
AL541_RS10060	COG5001	Diguanylate cyclase
AL541_RS10065	COG1032	radical SAM domain protein
AL541_RS10085	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AL541_RS10090	COG0463	Glycosyl transferase, family 2
AL541_RS10095	COG0745	RESPONSE REGULATOR receiver
AL541_RS10100	COG5002	protein histidine kinase activity
AL541_RS10100	COG3850	Histidine kinase
AL541_RS10155	COG0577	efflux transmembrane transporter activity
AL541_RS10155	COG1136	(ABC) transporter
AL541_RS10165	COG0577	efflux transmembrane transporter activity
AL541_RS10165	COG1136	(ABC) transporter
AL541_RS10175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL541_RS10195	COG3118	belongs to the thioredoxin family
AL541_RS10200	COG4232	protein-disulfide reductase activity
AL541_RS10235	COG2863	cytochrome
AL541_RS10240	COG3258	Cytochrome c
AL541_RS10245	COG2995	paraquat-inducible protein a
AL541_RS10250	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AL541_RS10250	COG3008	intermembrane lipid transfer
AL541_RS10270	COG4166	transmembrane transport
AL541_RS10280	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AL541_RS10285	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
AL541_RS10295	COG0539	negative regulation of cytoplasmic translation
AL541_RS10300	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AL541_RS10305	COG0616	signal peptide processing
AL541_RS10310	COG1028	Short-chain dehydrogenase reductase Sdr
AL541_RS10325	COG0587	DNA-directed DNA polymerase activity
AL541_RS10330	COG0835	chemotaxis
AL541_RS10330	COG0784	Response regulator, receiver
AL541_RS10335	COG1940	carbohydrate kinase activity
AL541_RS10340	COG0469	pyruvate kinase activity
AL541_RS10345	COG4667	esterase of the alpha-beta hydrolase superfamily
AL541_RS10360	COG0733	neurotransmitter:sodium symporter activity
AL541_RS10375	COG1263	PTS System
AL541_RS10375	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL541_RS10380	COG0084	hydrolase, TatD family'
AL541_RS10385	COG0470	DNA polymerase III
AL541_RS10390	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AL541_RS10395	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AL541_RS10425	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AL541_RS10430	COG0416	fatty acid biosynthetic process
AL541_RS10440	COG1399	metal-binding, possibly nucleic acid-binding protein
AL541_RS10445	COG0424	maF-like protein
AL541_RS10450	COG0564	pseudouridine synthase activity
AL541_RS10460	COG1530	ribonuclease E activity
AL541_RS10470	COG0659	secondary active sulfate transmembrane transporter activity
AL541_RS10475	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AL541_RS10480	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
AL541_RS10490	COG0572	uridine kinase
AL541_RS10500	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL541_RS10500	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL541_RS10520	COG2186	Transcriptional regulator
AL541_RS10525	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AL541_RS10530	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AL541_RS10535	COG0653	protein targeting
AL541_RS10540	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AL541_RS10545	COG3706	GGDEF domain
AL541_RS10550	COG0366	Alpha amylase catalytic
AL541_RS10555	COG1122	ATPase activity
AL541_RS10560	COG4120	Belongs to the binding-protein-dependent transport system permease family
AL541_RS10570	COG3092	negative regulation of chromosome organization
AL541_RS10575	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AL541_RS10580	COG0857	belongs to the CobB CobQ family
AL541_RS10580	COG0280	phosphate acetyltransferase
AL541_RS10590	COG0435	Glutathione S-transferase
AL541_RS10600	COG0444	Belongs to the ABC transporter superfamily
AL541_RS10605	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL541_RS10610	COG0601	transmembrane transport
AL541_RS10620	COG0314	molybdopterin synthase activity
AL541_RS10625	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AL541_RS10630	COG0315	cyclic pyranopterin monophosphate synthase activity
AL541_RS10635	COG0521	Mo-molybdopterin cofactor biosynthetic process
AL541_RS10640	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AL541_RS10645	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AL541_RS10650	COG2198	Histidine kinase
AL541_RS10655	COG2204	response regulator
AL541_RS10660	COG0556	nucleotide-excision repair
AL541_RS10670	COG1882	Formate acetyltransferase
AL541_RS10675	COG4657	Part of a membrane complex involved in electron transport
AL541_RS10680	COG2878	Part of a membrane complex involved in electron transport
AL541_RS10685	COG4656	Part of a membrane complex involved in electron transport
AL541_RS10690	COG4658	electron transport chain
AL541_RS10695	COG4659	FMN binding
AL541_RS10700	COG4660	Part of a membrane complex involved in electron transport
AL541_RS10705	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AL541_RS10710	COG0346	lactoylglutathione lyase activity
AL541_RS10720	COG2885	chlorophyll binding
AL541_RS10730	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AL541_RS10735	COG2056	Na+-H+ antiporter family
AL541_RS10755	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AL541_RS10780	COG1012	belongs to the aldehyde dehydrogenase family
AL541_RS10780	COG1454	alcohol dehydrogenase
AL541_RS10785	COG2095	MarC family integral membrane protein
AL541_RS10790	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL541_RS10795	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AL541_RS10800	COG1757	Na H antiporter
AL541_RS10815	COG3081	Nucleoid-associated protein
AL541_RS10820	COG3082	Protein of unknown function (DUF1414)
AL541_RS10835	COG0123	including yeast histone deacetylase and acetoin utilization protein
AL541_RS10850	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AL541_RS10855	COG0778	Nitroreductase
AL541_RS10865	COG0446	pyridine nucleotide-disulphide oxidoreductase
AL541_RS10865	COG1902	pentaerythritol trinitrate reductase activity
AL541_RS10870	COG0616	signal peptide processing
AL541_RS10875	COG0252	asparaginase activity
AL541_RS10880	COG3139	Protein of unknown function (DUF1315)
AL541_RS10890	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL541_RS10895	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AL541_RS10900	COG0676	glucose-6-phosphate 1-epimerase activity
AL541_RS10910	COG2226	methyltransferase
AL541_RS10930	COG1785	Belongs to the alkaline phosphatase family
AL541_RS10940	COG0346	lactoylglutathione lyase activity
AL541_RS10945	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AL541_RS10950	COG0668	transmembrane transport
AL541_RS10955	COG2983	Belongs to the UPF0260 family
AL541_RS10960	COG2261	transglycosylase associated protein
AL541_RS10970	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AL541_RS10975	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AL541_RS10990	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AL541_RS10995	COG2832	Protein of unknown function (DUF454)
AL541_RS11005	COG0745	RESPONSE REGULATOR receiver
AL541_RS11010	COG0583	DNA-binding transcription factor activity
AL541_RS11015	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AL541_RS11020	COG1286	toxin biosynthetic process
AL541_RS11025	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
AL541_RS11030	COG0285	dihydrofolate synthase activity
AL541_RS11035	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AL541_RS11045	COG0101	tRNA pseudouridine synthase activity
AL541_RS11055	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AL541_RS11060	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL541_RS11070	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AL541_RS11075	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AL541_RS11075	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL541_RS11080	COG0431	NADPH-dependent FMN reductase
AL541_RS11095	COG3101	peptidyl-lysine hydroxylation
AL541_RS11105	COG2860	membrane
AL541_RS11110	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AL541_RS11115	COG2890	protein-(glutamine-N5) methyltransferase activity
AL541_RS11120	COG2840	Smr protein MutS2
AL541_RS11125	COG2062	phosphohistidine phosphatase, SixA
AL541_RS11140	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL541_RS11140	COG1024	Enoyl-CoA hydratase
AL541_RS11145	COG0183	Belongs to the thiolase family
AL541_RS11170	COG2067	long-chain fatty acid transport protein
AL541_RS11180	COG3088	subunit of a heme lyase
AL541_RS11180	COG4235	cytochrome complex assembly
AL541_RS11190	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL541_RS11195	COG1138	Cytochrome C-type biogenesis protein
AL541_RS11200	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AL541_RS11205	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AL541_RS11210	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AL541_RS11215	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AL541_RS11220	COG4133	protoheme IX ABC transporter activity
AL541_RS11230	COG0835	chemotaxis
AL541_RS11240	COG1192	Involved in chromosome partitioning
AL541_RS11245	COG2201	protein-glutamate methylesterase activity
AL541_RS11250	COG0643	Histidine kinase
AL541_RS11250	COG0784	Response regulator, receiver
AL541_RS11250	COG2198	Histidine kinase
AL541_RS11255	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AL541_RS11290	COG1684	flagellar biosynthetic protein fliR
AL541_RS11295	COG1987	bacterial-type flagellum assembly
AL541_RS11350	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AL541_RS11360	COG1677	Flagellar hook-basal body complex protein FliE
AL541_RS11380	COG1516	flagellar protein fliS
AL541_RS11390	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AL541_RS11395	COG1334	flagellar protein FlaG
AL541_RS11400	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AL541_RS11405	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AL541_RS11415	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AL541_RS11420	COG2837	iron assimilation
AL541_RS11445	COG1393	Belongs to the ArsC family
AL541_RS11450	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AL541_RS11465	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AL541_RS11470	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL541_RS11480	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AL541_RS11495	COG4783	chaperone-mediated protein folding
AL541_RS11500	COG1393	Belongs to the ArsC family
AL541_RS11520	COG2233	PERMEase
AL541_RS11525	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AL541_RS11530	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AL541_RS11535	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AL541_RS11540	COG0121	glutamine amidotransferase
AL541_RS11545	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AL541_RS11550	COG1960	acyl-CoA dehydrogenase activity
AL541_RS11585	COG0328	RNA-DNA hybrid ribonuclease activity
AL541_RS11590	COG2226	methyltransferase
AL541_RS11595	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AL541_RS11600	COG1388	LysM domain
AL541_RS11600	COG0741	lytic transglycosylase activity
AL541_RS11610	COG3021	interspecies interaction between organisms
AL541_RS11615	COG0347	Belongs to the P(II) protein family
AL541_RS11630	COG0825	malonyl-CoA metabolic process
AL541_RS11635	COG0587	DNA-directed DNA polymerase activity
AL541_RS11645	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AL541_RS11650	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AL541_RS11660	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AL541_RS11665	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
AL541_RS11675	COG0750	zinc metalloprotease
AL541_RS11680	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AL541_RS11685	COG0575	Belongs to the CDS family
AL541_RS11690	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AL541_RS11695	COG0233	cytoplasmic translational termination
AL541_RS11700	COG0528	UMP kinase activity
AL541_RS11705	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AL541_RS11710	COG0052	Belongs to the universal ribosomal protein uS2 family
AL541_RS11715	COG0024	Methionine aminopeptidase
AL541_RS11720	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AL541_RS11730	COG0564	pseudouridine synthase activity
AL541_RS11735	COG3098	single-species biofilm formation
AL541_RS11770	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AL541_RS11775	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL541_RS11800	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AL541_RS11810	COG0254	rRNA binding
AL541_RS11815	COG1720	tRNA m6t6A37 methyltransferase activity
AL541_RS11820	COG0442	prolyl-tRNA aminoacylation
AL541_RS11840	COG0733	neurotransmitter:sodium symporter activity
AL541_RS11855	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AL541_RS11860	COG0514	ATP-dependent DNA helicase (RecQ)
AL541_RS11865	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AL541_RS11885	COG1477	protein flavinylation
AL541_RS11890	COG2871	sodium ion transport
AL541_RS11895	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AL541_RS11900	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AL541_RS11905	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AL541_RS11910	COG1805	sodium ion transport
AL541_RS11915	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AL541_RS11925	COG0271	Belongs to the BolA IbaG family
AL541_RS11930	COG2813	Specifically methylates the guanine in position
AL541_RS11935	COG3056	Lipoprotein
AL541_RS11955	COG1595	DNA-templated transcription, initiation
AL541_RS11980	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AL541_RS11985	COG0693	protein deglycase activity
AL541_RS11990	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AL541_RS11995	COG3706	GGDEF domain
AL541_RS12000	COG2166	iron-sulfur cluster assembly
AL541_RS12005	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AL541_RS12010	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AL541_RS12025	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AL541_RS12025	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AL541_RS12045	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AL541_RS12050	COG1074	ATP-dependent DNA helicase activity
AL541_RS12060	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AL541_RS12080	COG3141	response to X-ray
AL541_RS12095	COG2171	N-acyltransferase activity
AL541_RS12100	COG0584	glycerophosphoryl diester phosphodiesterase
AL541_RS12105	COG2271	Major facilitator Superfamily
AL541_RS12115	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AL541_RS12120	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AL541_RS12125	COG1349	DNA-binding transcription factor activity
AL541_RS12130	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AL541_RS12135	COG0598	Magnesium transport protein CorA
AL541_RS12155	COG1609	Transcriptional regulator
AL541_RS12160	COG0583	DNA-binding transcription factor activity
AL541_RS12200	COG1022	Amp-dependent synthetase and ligase
AL541_RS12210	COG0583	DNA-binding transcription factor activity
AL541_RS12215	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AL541_RS12220	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AL541_RS12230	COG0560	Phosphoserine phosphatase
AL541_RS12240	COG0813	purine-nucleoside phosphorylase activity
AL541_RS12245	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AL541_RS12250	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AL541_RS12255	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AL541_RS12260	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AL541_RS12265	COG0084	hydrolase, TatD family'
AL541_RS12295	COG3153	acetyltransferase
AL541_RS12300	COG3154	lipid carrier protein
AL541_RS12315	COG0826	peptidase U32
AL541_RS12320	COG0826	peptidase U32
AL541_RS12325	COG0534	Mate efflux family protein
AL541_RS12340	COG1185	polyribonucleotide nucleotidyltransferase activity
AL541_RS12345	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AL541_RS12350	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AL541_RS12355	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AL541_RS12360	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AL541_RS12365	COG0195	Participates in both transcription termination and antitermination
AL541_RS12370	COG0779	Required for maturation of 30S ribosomal subunits
AL541_RS12385	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AL541_RS12395	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AL541_RS12400	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AL541_RS12405	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AL541_RS12410	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AL541_RS12415	COG1534	Rna-binding protein
AL541_RS12420	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AL541_RS12425	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL541_RS12430	COG2027	D-alanyl-D-alanine carboxypeptidase
AL541_RS12440	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AL541_RS12445	COG0739	heme binding
AL541_RS12470	COG0628	permease
AL541_RS12480	COG2205	protein histidine kinase activity
AL541_RS12480	COG0784	Response regulator, receiver
AL541_RS12485	COG0747	negative chemotaxis
AL541_RS12495	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL541_RS12500	COG0444	Belongs to the ABC transporter superfamily
AL541_RS12505	COG4608	Belongs to the ABC transporter superfamily
AL541_RS12515	COG2971	BadF BadG BcrA BcrD
AL541_RS12530	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AL541_RS12535	COG3842	ATPase activity
AL541_RS12545	COG1840	ABC-type Fe3 transport system, periplasmic component
AL541_RS12550	COG0004	ammonium transporteR
AL541_RS12560	COG3112	Uncharacterised protein family (UPF0231)
AL541_RS12565	COG1049	propionate catabolic process, 2-methylcitrate cycle
AL541_RS12570	COG1752	Esterase of the alpha-beta hydrolase superfamily
AL541_RS12575	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AL541_RS12580	COG1643	Atp-dependent helicase
AL541_RS12585	COG1489	DNA binding
AL541_RS12595	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AL541_RS12605	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AL541_RS12610	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AL541_RS12615	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AL541_RS12620	COG1560	Kdo2-lipid A biosynthetic process
AL541_RS12630	COG0842	Transport permease protein
AL541_RS12635	COG1131	(ABC) transporter
AL541_RS12640	COG0659	secondary active sulfate transmembrane transporter activity
AL541_RS12645	COG0288	reversible hydration of carbon dioxide
AL541_RS12660	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL541_RS12665	COG0508	dehydrogenase complex catalyzes the overall conversion of
AL541_RS12670	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AL541_RS12675	COG2186	Transcriptional regulator
AL541_RS12685	COG0157	Belongs to the NadC ModD family
AL541_RS12695	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AL541_RS12700	COG1459	type II secretion system
AL541_RS12710	COG0237	dephospho-CoA kinase activity
AL541_RS12715	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
AL541_RS12720	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AL541_RS12735	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AL541_RS12740	COG0228	four-way junction DNA binding
AL541_RS12745	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AL541_RS12750	COG4137	Cytochrome C assembly protein
AL541_RS12755	COG4536	flavin adenine dinucleotide binding
AL541_RS12760	COG1854	S-ribosylhomocysteine lyase activity
AL541_RS12775	COG0612	Peptidase, M16
AL541_RS12780	COG1238	metal cluster binding
AL541_RS12790	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
AL541_RS12795	COG0511	ligase activity, forming carbon-carbon bonds
AL541_RS12795	COG5016	pyruvate
AL541_RS12800	COG3630	sodium ion export across plasma membrane
AL541_RS12860	COG0527	aspartate kinase activity
AL541_RS12865	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AL541_RS12870	COG2137	regulation of response to DNA damage stimulus
AL541_RS12875	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AL541_RS12880	COG1546	Belongs to the CinA family
AL541_RS12885	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AL541_RS12890	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AL541_RS12900	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AL541_RS12905	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AL541_RS12915	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AL541_RS12920	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AL541_RS12925	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AL541_RS12930	COG0148	phosphopyruvate hydratase activity
AL541_RS12935	COG0504	CTP synthase activity
AL541_RS12940	COG3956	TIGRFAM MazG family protein
AL541_RS12945	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AL541_RS12955	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AL541_RS12970	COG0736	holo-[acyl-carrier-protein] synthase activity
AL541_RS12975	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AL541_RS12980	COG1381	Involved in DNA repair and RecF pathway recombination
AL541_RS12985	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AL541_RS12995	COG0681	Belongs to the peptidase S26 family
AL541_RS13000	COG0481	GTPase activity
AL541_RS13005	COG3086	response to oxidative stress
AL541_RS13020	COG1595	DNA-templated transcription, initiation
AL541_RS13030	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AL541_RS13040	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AL541_RS13045	COG0354	folic acid binding
AL541_RS13060	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL541_RS13065	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL541_RS13070	COG3079	Belongs to the UPF0149 family
AL541_RS13080	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
AL541_RS13090	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AL541_RS13095	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AL541_RS13100	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL541_RS13110	COG0583	DNA-binding transcription factor activity
AL541_RS13125	COG0668	transmembrane transport
AL541_RS13130	COG0191	fructose-bisphosphate aldolase activity
AL541_RS13145	COG4771	TonB-dependent receptor
AL541_RS13150	COG0583	DNA-binding transcription factor activity
AL541_RS13155	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AL541_RS13165	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AL541_RS13180	COG2356	endonuclease I
AL541_RS13185	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AL541_RS13190	COG0189	ligase activity
AL541_RS13195	COG1678	Uncharacterized ACR, COG1678
AL541_RS13200	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AL541_RS13215	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AL541_RS13220	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AL541_RS13225	COG0762	integral membrane protein
AL541_RS13230	COG1872	DUF167
AL541_RS13240	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AL541_RS13245	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AL541_RS13250	COG2066	Belongs to the glutaminase family
AL541_RS13260	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AL541_RS13270	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
AL541_RS13315	COG0840	transmembrane signaling receptor activity
AL541_RS13395	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AL541_RS13400	COG1609	Transcriptional regulator
AL541_RS13405	COG3394	polysaccharide catabolic process
AL541_RS13410	COG1486	melibiose metabolic process
AL541_RS13415	COG1447	Phosphotransferase system cellobiose-specific component IIA
AL541_RS13420	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AL541_RS13425	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AL541_RS13430	COG0726	polysaccharide deacetylase
AL541_RS13525	COG1028	Short-chain dehydrogenase reductase Sdr
AL541_RS13540	COG0795	lipopolysaccharide-transporting ATPase activity
AL541_RS13545	COG0795	lipopolysaccharide-transporting ATPase activity
AL541_RS13550	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AL541_RS13555	COG2927	DNA polymerase III (CHI subunit)
AL541_RS13560	COG0525	valine-tRNA ligase activity
AL541_RS13570	COG0456	acetyltransferase
AL541_RS13600	COG0540	Belongs to the ATCase OTCase family
AL541_RS13605	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
AL541_RS13610	COG0251	oxidation-reduction process
AL541_RS13615	COG0204	Acyl-transferase
AL541_RS13620	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AL541_RS13625	COG5007	Belongs to the BolA IbaG family
AL541_RS13635	COG2854	intermembrane phospholipid transfer
AL541_RS13640	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AL541_RS13645	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AL541_RS13650	COG1127	ABC transporter
AL541_RS13660	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AL541_RS13660	COG0517	IMP dehydrogenase activity
AL541_RS13670	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AL541_RS13675	COG1137	ATPase activity
AL541_RS13685	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AL541_RS13690	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL541_RS13695	COG1660	Displays ATPase and GTPase activities
AL541_RS13700	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL541_RS13705	COG2239	Acts as a magnesium transporter
AL541_RS13710	COG0312	modulator of DNA gyrase
AL541_RS13715	COG3028	Belongs to the UPF0307 family
AL541_RS13720	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AL541_RS13725	COG0564	pseudouridine synthase activity
AL541_RS13735	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AL541_RS13740	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AL541_RS13745	COG0312	modulator of DNA gyrase
AL541_RS13750	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AL541_RS13755	COG3164	Protein of unknown function
AL541_RS13765	COG0424	maF-like protein
AL541_RS13770	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AL541_RS13775	COG1792	Involved in formation and maintenance of cell shape
AL541_RS13780	COG1077	Cell shape determining protein MreB Mrl
AL541_RS13815	COG2165	general secretion pathway protein
AL541_RS13825	COG1459	type II secretion system
AL541_RS13830	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AL541_RS13840	COG3267	Type II secretory pathway component ExeA
AL541_RS13840	COG3409	Peptidoglycan-binding domain 1 protein
AL541_RS13845	COG1450	Type ii and iii secretion system protein
AL541_RS13865	COG2199	diguanylate cyclase activity
AL541_RS13865	COG2200	EAL domain
AL541_RS13870	COG0629	single-stranded DNA binding
AL541_RS13885	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AL541_RS13895	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AL541_RS13905	COG0527	aspartate kinase activity
AL541_RS13910	COG1410	methionine synthase
AL541_RS13910	COG0646	methionine synthase
AL541_RS13975	COG0175	sulfate reduction
AL541_RS13980	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AL541_RS13985	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AL541_RS14005	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AL541_RS14010	COG0735	belongs to the Fur family
AL541_RS14020	COG0166	Belongs to the GPI family
AL541_RS14025	COG0432	Pfam Uncharacterised protein family UPF0047
AL541_RS14030	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AL541_RS14055	COG2965	DNA replication, synthesis of RNA primer
AL541_RS14060	COG0360	Binds together with S18 to 16S ribosomal RNA
AL541_RS14065	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AL541_RS14070	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AL541_RS14080	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AL541_RS14085	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AL541_RS14115	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AL541_RS14125	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AL541_RS14125	COG0678	peroxiredoxin activity
AL541_RS14130	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL541_RS14140	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AL541_RS14140	COG0165	Argininosuccinate lyase
AL541_RS14145	COG0137	argininosuccinate synthase activity
AL541_RS14155	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AL541_RS14165	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AL541_RS14175	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AL541_RS14180	COG0527	aspartate kinase activity
AL541_RS14180	COG0460	homoserine dehydrogenase
AL541_RS14185	COG0626	cystathionine gamma-synthase activity
AL541_RS14190	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
AL541_RS14195	COG0281	malic enzyme
AL541_RS14210	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AL541_RS14215	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AL541_RS14235	COG2923	Belongs to the DsrF TusC family
AL541_RS14240	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AL541_RS14245	COG2964	Protein conserved in bacteria
AL541_RS14250	COG0545	Peptidyl-prolyl cis-trans isomerase
AL541_RS14265	COG1446	asparaginase
AL541_RS14275	COG1047	Peptidyl-prolyl cis-trans
AL541_RS14290	COG2249	NAD(P)H dehydrogenase (quinone) activity
AL541_RS14295	COG0488	(ABC) transporter
AL541_RS14305	COG0429	hydrolase of the alpha beta-hydrolase fold
AL541_RS14315	COG3954	Phosphoribulokinase
AL541_RS14320	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL541_RS14340	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AL541_RS14345	COG0512	Glutamine amidotransferase of anthranilate synthase
AL541_RS14360	COG0180	Tryptophanyl-tRNA synthetase
AL541_RS14365	COG0546	phosphoglycolate phosphatase activity
AL541_RS14370	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AL541_RS14375	COG0557	exoribonuclease II activity
AL541_RS14380	COG1959	2 iron, 2 sulfur cluster binding
AL541_RS14385	COG1017	nitric oxide dioxygenase activity
AL541_RS14385	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL541_RS14390	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AL541_RS14400	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AL541_RS14405	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
AL541_RS14410	COG0330	HflC and HflK could
AL541_RS14415	COG0330	HflC and HflK could
AL541_RS14420	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AL541_RS14430	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AL541_RS14435	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AL541_RS14445	COG0802	atpase or kinase
AL541_RS14455	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AL541_RS14520	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AL541_RS14525	COG1162	GTPase activity
AL541_RS14530	COG0688	phosphatidylethanolamine metabolic process
AL541_RS14535	COG0471	metal ion transport
AL541_RS14545	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AL541_RS14550	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AL541_RS14555	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AL541_RS14560	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AL541_RS14565	COG1045	serine acetyltransferase
AL541_RS14570	COG4942	peptidase
AL541_RS14590	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AL541_RS14595	COG1053	succinate dehydrogenase
AL541_RS14600	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AL541_RS14605	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
AL541_RS14610	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
AL541_RS14625	COG1509	lysine 2,3-aminomutase activity
AL541_RS14630	COG1285	pathogenesis
AL541_RS14640	COG0459	protein refolding
AL541_RS14650	COG0534	Mate efflux family protein
AL541_RS14655	COG0205	6-phosphofructokinase activity
AL541_RS14665	COG3678	ATP-independent chaperone mediated protein folding
AL541_RS14670	COG0745	RESPONSE REGULATOR receiver
AL541_RS14675	COG2205	protein histidine kinase activity
AL541_RS14685	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AL541_RS14690	COG3030	protein affecting phage T7 exclusion by the F plasmid
AL541_RS14695	COG1027	Aspartate ammonia-lyase
AL541_RS14700	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AL541_RS14705	COG4232	protein-disulfide reductase activity
AL541_RS14715	COG3263	regulation of cellular component size
AL541_RS14725	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AL541_RS14750	COG2814	Major facilitator Superfamily
AL541_RS14765	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AL541_RS14770	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AL541_RS14775	COG0511	ligase activity, forming carbon-carbon bonds
AL541_RS14780	COG0439	Biotin carboxylase
AL541_RS14790	COG2264	protein methyltransferase activity
AL541_RS14795	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AL541_RS14800	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AL541_RS14810	COG0488	(ABC) transporter
AL541_RS14865	COG1982	Orn Lys Arg decarboxylase major
AL541_RS14870	COG0531	amino acid
AL541_RS14880	COG3710	Transcriptional regulator
AL541_RS14885	COG0789	Transcriptional regulator
AL541_RS14895	COG0138	bifunctional purine biosynthesis protein purh
AL541_RS14900	COG0151	Belongs to the GarS family
AL541_RS14915	COG1253	flavin adenine dinucleotide binding
AL541_RS14920	COG3068	Protein conserved in bacteria
AL541_RS14930	COG1573	uracil-dna glycosylase
AL541_RS14935	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AL541_RS14940	COG2816	NAD+ diphosphatase activity
AL541_RS14945	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
AL541_RS14950	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AL541_RS14955	COG0085	RNA polymerase activity
AL541_RS14960	COG0222	ribosome binding
AL541_RS14965	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AL541_RS14980	COG0250	Participates in transcription elongation, termination and antitermination
AL541_RS14985	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AL541_RS14995	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AL541_RS15030	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AL541_RS15030	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AL541_RS15035	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AL541_RS15045	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AL541_RS15120	COG4206	TonB-dependent receptor
AL541_RS15140	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL541_RS15145	COG0534	Mate efflux family protein
AL541_RS15150	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AL541_RS15160	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AL541_RS15170	COG2937	Belongs to the GPAT DAPAT family
AL541_RS15175	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AL541_RS15180	COG3161	chorismate lyase activity
AL541_RS15185	COG1580	Controls the rotational direction of flagella during chemotaxis
AL541_RS15190	COG0705	Rhomboid family
AL541_RS15195	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AL541_RS15210	COG2177	Part of the ABC transporter FtsEX involved in
AL541_RS15215	COG2884	Cell division ATP-binding protein ftsE
AL541_RS15220	COG0552	protein localization to endoplasmic reticulum
AL541_RS15225	COG0742	ribosomal rna small subunit methyltransferase
AL541_RS15235	COG2095	MarC family integral membrane protein
AL541_RS15280	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AL541_RS15285	COG0640	Transcriptional regulator
AL541_RS15290	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AL541_RS15295	COG1280	lysine exporter protein (LysE YggA)
AL541_RS15300	COG2267	carboxylic ester hydrolase activity
AL541_RS15305	COG0561	phosphatase activity
AL541_RS15320	COG3148	PFAM DTW domain containing protein
AL541_RS15325	COG2200	EAL domain
AL541_RS15325	COG3287	FIST C domain
AL541_RS15325	COG2199	diguanylate cyclase activity
AL541_RS15330	COG1011	Hydrolase
AL541_RS15335	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AL541_RS15350	COG0019	diaminopimelate decarboxylase activity
AL541_RS15360	COG1965	Belongs to the frataxin family
AL541_RS15365	COG3072	Adenylate cyclase
AL541_RS15370	COG0181	hydroxymethylbilane synthase activity
AL541_RS15375	COG1587	Uroporphyrinogen-III synthase
AL541_RS15380	COG2959	enzyme of heme biosynthesis
AL541_RS15385	COG3071	HemY protein
AL541_RS15430	COG0633	Ferredoxin
AL541_RS15435	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AL541_RS15450	COG3118	belongs to the thioredoxin family
AL541_RS15455	COG0513	Belongs to the DEAD box helicase family
AL541_RS15460	COG0248	Ppx GppA phosphatase
AL541_RS15470	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AL541_RS15485	COG0514	ATP-dependent DNA helicase (RecQ)
AL541_RS15490	COG2962	Rard protein
AL541_RS15500	COG1280	lysine exporter protein (LysE YggA)
AL541_RS15505	COG0405	Gamma-glutamyltransferase
AL541_RS15515	COG0210	DNA helicase
AL541_RS15525	COG3220	belongs to the UPF0276 family
AL541_RS15555	COG0006	proline dipeptidase activity
AL541_RS15555	COG0006	proline dipeptidase activity
AL541_RS15575	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AL541_RS15595	COG2132	Multicopper oxidase
AL541_RS15640	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AL541_RS15660	COG0009	L-threonylcarbamoyladenylate synthase
AL541_RS15665	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AL541_RS15670	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AL541_RS15675	COG0551	DNA topoisomerase type I activity
AL541_RS15685	COG2922	Belongs to the Smg family
AL541_RS15690	COG0758	DNA mediated transformation
AL541_RS15700	COG0242	peptide deformylase activity
AL541_RS15705	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AL541_RS15710	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AL541_RS15710	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AL541_RS15715	COG0569	domain protein
AL541_RS15720	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AL541_RS15730	COG1272	protein, Hemolysin III
AL541_RS15735	COG4326	sporulation control protein
AL541_RS15745	COG3084	Protein conserved in bacteria
AL541_RS15755	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AL541_RS15760	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AL541_RS15765	COG0204	Acyl-transferase
AL541_RS15775	COG0606	chelatase, subunit chli
AL541_RS15785	COG3978	acetolactate synthase activity
AL541_RS15790	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AL541_RS15795	COG0129	dihydroxy-acid dehydratase activity
AL541_RS15805	COG0583	DNA-binding transcription factor activity
AL541_RS15810	COG2814	Major facilitator Superfamily
AL541_RS15815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL541_RS15820	COG0765	amino acid transport
AL541_RS15830	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AL541_RS15835	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AL541_RS15840	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AL541_RS15845	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AL541_RS15850	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AL541_RS15855	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AL541_RS15865	COG0356	it plays a direct role in the translocation of protons across the membrane
AL541_RS15870	COG3312	ion transport
AL541_RS15875	COG1475	DNA binding
AL541_RS15880	COG1192	Involved in chromosome partitioning
AL541_RS15885	COG0357	Ribosomal RNA small subunit methyltransferase G
AL541_RS15890	COG0445	tRNA wobble uridine modification
AL541_RS15895	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AL541_RS15905	COG0706	membrane insertase activity
AL541_RS15915	COG0594	ribonuclease P activity
AL541_RS15925	COG1126	abc transporter atp-binding protein
AL541_RS15945	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AL541_RS15950	COG0592	DNA-directed DNA polymerase activity
AL541_RS15960	COG0187	DNA topoisomerase II activity
AL541_RS15980	COG0071	Belongs to the small heat shock protein (HSP20) family
AL541_RS15985	COG3977	Valine--pyruvate aminotransferase
AL541_RS15990	COG0366	Alpha amylase catalytic
AL541_RS16005	COG2119	membrane
AL541_RS16015	COG0425	Belongs to the sulfur carrier protein TusA family
AL541_RS16030	COG0604	alcohol dehydrogenase
AL541_RS16035	COG0183	Belongs to the thiolase family
AL541_RS16045	COG1739	Uncharacterized protein family UPF0029
AL541_RS16050	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AL541_RS16095	COG0583	DNA-binding transcription factor activity
AL541_RS16100	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AL541_RS16105	COG2960	long-chain fatty acid transporting porin activity
AL541_RS16110	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL541_RS16115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL541_RS16175	COG4166	transmembrane transport
AL541_RS16180	COG0601	transmembrane transport
AL541_RS16185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL541_RS16225	COG1609	Transcriptional regulator
AL541_RS16230	COG0583	DNA-binding transcription factor activity
AL541_RS16245	COG0129	dihydroxy-acid dehydratase activity
AL541_RS16250	COG3265	gluconokinase activity
AL541_RS16255	COG2610	gluconate transmembrane transporter activity
AL541_RS16260	COG0800	Aldolase
AL541_RS16265	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AL541_RS16270	COG0583	DNA-binding transcription factor activity
AL541_RS16275	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL541_RS16280	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AL541_RS16290	COG1522	sequence-specific DNA binding
AL541_RS16295	COG5001	Diguanylate cyclase
AL541_RS16295	COG5002	protein histidine kinase activity
AL541_RS16315	COG0589	response to stress
AL541_RS16320	COG1528	Iron-storage protein
AL541_RS16330	COG2081	HI0933 family
AL541_RS16360	COG1597	lipid kinase activity
AL541_RS16390	COG0628	permease
AL541_RS16405	COG1322	Protein conserved in bacteria
AL541_RS16410	COG2226	methyltransferase
AL541_RS16415	COG3165	ubiquinone biosynthetic process from chorismate
AL541_RS16420	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AL541_RS16430	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AL541_RS16435	COG0805	protein transport
AL541_RS16445	COG0084	hydrolase, TatD family'
AL541_RS16460	COG0456	acetyltransferase
AL541_RS16470	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AL541_RS16470	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AL541_RS16475	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AL541_RS16510	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AL541_RS16520	COG2204	response regulator
AL541_RS16525	COG3852	Histidine kinase
AL541_RS16535	COG0174	glutamine synthetase
AL541_RS16540	COG1217	gtp-binding protein TYPA
AL541_RS16545	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AL541_RS16555	COG1295	ribonuclease BN
AL541_RS16560	COG1490	D-aminoacyl-tRNA deacylase activity
AL541_RS16565	COG0456	acetyltransferase
AL541_RS16575	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AL541_RS16580	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AL541_RS16585	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AL541_RS16590	COG3031	protein transport across the cell outer membrane
AL541_RS16600	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AL541_RS16605	COG1459	type II secretion system
AL541_RS16610	COG2165	general secretion pathway protein
AL541_RS16615	COG2165	general secretion pathway protein
AL541_RS16620	COG2165	general secretion pathway protein
AL541_RS16625	COG4795	General secretion pathway protein
AL541_RS16630	COG3156	type II secretion system protein K
AL541_RS16635	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
AL541_RS16640	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
AL541_RS16650	COG1218	3'(2'),5'-bisphosphate nucleotidase
AL541_RS16655	COG0494	nUDIX hydrolase
AL541_RS16665	COG1040	competence protein
AL541_RS16680	COG2183	response to ionizing radiation
AL541_RS16690	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AL541_RS16710	COG2233	PERMEase
AL541_RS16715	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AL541_RS16720	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AL541_RS16725	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AL541_RS16730	COG1758	RNA polymerase activity
AL541_RS16735	COG0194	GDP metabolic process
AL541_RS16755	COG0848	biopolymer transport protein
AL541_RS16760	COG0811	peptide transport
AL541_RS16785	COG4174	ABC transporter (Permease)
AL541_RS16790	COG4239	(ABC) transporter, permease
AL541_RS16795	COG0747	negative chemotaxis
AL541_RS16800	COG0444	Belongs to the ABC transporter superfamily
AL541_RS16805	COG4608	Belongs to the ABC transporter superfamily
AL541_RS16815	COG1561	YicC-like family, N-terminal region
AL541_RS16825	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AL541_RS16830	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AL541_RS16835	COG1560	Kdo2-lipid A biosynthetic process
AL541_RS16840	COG1309	transcriptional regulator
AL541_RS16845	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AL541_RS16860	COG2003	Belongs to the UPF0758 family
AL541_RS16885	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AL541_RS16900	COG0463	Glycosyl transferase, family 2
AL541_RS16905	COG0859	PFAM glycosyl transferase family 9
AL541_RS16910	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AL541_RS16915	COG3642	lipopolysaccharide core region biosynthetic process
AL541_RS16945	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AL541_RS16955	COG1028	Short-chain dehydrogenase reductase Sdr
AL541_RS16960	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AL541_RS16975	COG1519	Transferase
AL541_RS16980	COG0859	PFAM glycosyl transferase family 9
AL541_RS16990	COG1560	Kdo2-lipid A biosynthetic process
AL541_RS17000	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL541_RS17060	COG1215	transferase activity, transferring glycosyl groups
AL541_RS17070	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
AL541_RS17075	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL541_RS17095	COG1482	cell wall glycoprotein biosynthetic process
AL541_RS17110	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AL541_RS17130	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AL541_RS17135	COG0149	triose-phosphate isomerase activity
AL541_RS17140	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL541_RS17150	COG2067	long-chain fatty acid transport protein
AL541_RS17160	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL541_RS17170	COG1505	serine-type exopeptidase activity
AL541_RS17175	COG0488	(ABC) transporter
AL541_RS17180	COG0589	response to stress
AL541_RS17185	COG2249	NAD(P)H dehydrogenase (quinone) activity
AL541_RS17205	COG0366	Alpha amylase catalytic
AL541_RS17210	COG0789	Transcriptional regulator
AL541_RS17215	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL541_RS17225	COG4934	collagen metabolic process
AL541_RS17235	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AL541_RS17240	COG0583	DNA-binding transcription factor activity
AL541_RS17265	COG2610	gluconate transmembrane transporter activity
AL541_RS17270	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL541_RS17275	COG3622	Belongs to the hyi family
AL541_RS17280	COG0235	Class ii aldolase
AL541_RS17285	COG3395	kinase activity
AL541_RS17290	COG2084	Dehydrogenase
AL541_RS17295	COG1349	DNA-binding transcription factor activity
AL541_RS17305	COG0747	negative chemotaxis
AL541_RS17310	COG4608	Belongs to the ABC transporter superfamily
AL541_RS17315	COG0444	Belongs to the ABC transporter superfamily
AL541_RS17320	COG0534	Mate efflux family protein
AL541_RS17325	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL541_RS17330	COG0784	Response regulator, receiver
AL541_RS17330	COG0835	chemotaxis
AL541_RS17340	COG0748	coenzyme F420 binding
AL541_RS17345	COG3721	Heme iron utilization protein
AL541_RS17355	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AL541_RS17360	COG0811	peptide transport
AL541_RS17365	COG0848	biopolymer transport protein
AL541_RS17375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL541_RS17380	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AL541_RS17420	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AL541_RS17430	COG0633	Ferredoxin
AL541_RS17430	COG3217	Mosc domain protein beta barrel domain protein
AL541_RS17430	COG0633	Ferredoxin
AL541_RS17430	COG3217	Mosc domain protein beta barrel domain protein
AL541_RS17435	COG0401	homolog of Blt101
AL541_RS17445	COG0418	dihydroorotase activity
AL541_RS17450	COG2354	Protein conserved in bacteria
AL541_RS17460	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL541_RS17465	COG4605	iron ion homeostasis
AL541_RS17470	COG4607	ABC-type enterochelin transport system periplasmic component
AL541_RS17475	COG4774	siderophore transport
AL541_RS17480	COG1132	(ABC) transporter
AL541_RS17480	COG2375	cellular response to nickel ion
AL541_RS17510	COG3833	ABC-type maltose transport systems, permease component
AL541_RS17515	COG1175	transmembrane transport
AL541_RS17525	COG3842	ATPase activity
AL541_RS17530	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AL541_RS17545	COG0489	protein tyrosine kinase activity
AL541_RS17545	COG3206	protein involved in exopolysaccharide biosynthesis
AL541_RS17585	COG3097	Belongs to the UPF0267 family
AL541_RS17590	COG1309	transcriptional regulator
AL541_RS17595	COG2130	NADP-dependent
AL541_RS17605	COG0753	catalase activity
AL541_RS17610	COG2084	Dehydrogenase
AL541_RS17640	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL541_RS17645	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
AL541_RS17655	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL541_RS17660	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AL541_RS17665	COG1012	belongs to the aldehyde dehydrogenase family
AL541_RS17680	COG0583	DNA-binding transcription factor activity
AL541_RS17685	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AL541_RS17690	COG0569	domain protein
AL541_RS17700	COG2205	protein histidine kinase activity
AL541_RS17705	COG1132	(ABC) transporter
AL541_RS17710	COG4774	siderophore transport
AL541_RS17715	COG1120	ATPase activity
AL541_RS17720	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AL541_RS17755	COG2197	response regulator
AL541_RS17770	COG0714	Associated with various cellular activities
AL541_RS17790	COG2304	oxidoreductase activity
AL541_RS17805	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AL541_RS17810	COG0581	inorganic phosphate transmembrane transporter activity
AL541_RS17815	COG0573	inorganic phosphate transmembrane transporter activity
AL541_RS17845	COG4771	TonB-dependent receptor
AL541_RS17850	COG1770	oligopeptidase
AL541_RS17855	COG0513	Belongs to the DEAD box helicase family
AL541_RS17865	COG1388	LysM domain
AL541_RS17865	COG1376	ErfK ybiS ycfS ynhG family protein
AL541_RS17870	COG0415	Belongs to the DNA photolyase family
AL541_RS17875	COG0789	Transcriptional regulator
AL541_RS17880	COG3272	Protein of unknown function (DUF1722)
AL541_RS17885	COG0813	purine-nucleoside phosphorylase activity
AL541_RS17910	COG1566	PFAM secretion protein HlyD family protein
AL541_RS17915	COG4720	Psort location CytoplasmicMembrane, score
AL541_RS17920	COG1122	ATPase activity
AL541_RS17940	COG0348	domain, Protein
AL541_RS17945	COG0437	4 iron, 4 sulfur cluster binding
AL541_RS17950	COG1247	-acetyltransferase
AL541_RS17970	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL541_RS17975	COG0840	transmembrane signaling receptor activity
AL541_RS17980	COG1067	ATP-dependent peptidase activity
AL541_RS17990	COG4172	Belongs to the ABC transporter superfamily
AL541_RS17995	COG1505	serine-type exopeptidase activity
AL541_RS18000	COG0583	DNA-binding transcription factor activity
AL541_RS18005	COG1620	l-lactate permease
AL541_RS18010	COG1304	FMN binding
AL541_RS18020	COG0668	transmembrane transport
AL541_RS18055	COG1063	alcohol dehydrogenase
AL541_RS18060	COG0156	8-amino-7-oxononanoate synthase activity
AL541_RS18065	COG5001	Diguanylate cyclase
AL541_RS18065	COG3300	MHYT domain
AL541_RS18090	COG0745	RESPONSE REGULATOR receiver
AL541_RS18115	COG0346	lactoylglutathione lyase activity
AL541_RS18175	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AL541_RS18215	COG1987	bacterial-type flagellum assembly
AL541_RS18225	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AL541_RS18240	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AL541_RS18250	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AL541_RS18255	COG1516	flagellar protein fliS
AL541_RS18270	COG1580	Controls the rotational direction of flagella during chemotaxis
AL541_RS18275	COG1191	sigma factor activity
AL541_RS18280	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AL541_RS18285	COG1360	Flagellar Motor Protein
AL541_RS18320	COG1882	Formate acetyltransferase
AL541_RS18325	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AL541_RS18330	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AL541_RS18350	COG2205	protein histidine kinase activity
AL541_RS18355	COG0745	RESPONSE REGULATOR receiver
AL541_RS18380	COG2814	Major facilitator Superfamily
AL541_RS18425	COG0628	permease
AL541_RS18430	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
AL541_RS18450	COG4628	conserved protein (DUF2132)
AL541_RS18455	COG0583	DNA-binding transcription factor activity
AL541_RS18480	COG1686	Belongs to the peptidase S11 family
AL541_RS18490	COG1054	Belongs to the UPF0176 family
AL541_RS18500	COG0415	Belongs to the DNA photolyase family
AL541_RS18505	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AL541_RS18510	COG3397	chitin binding
AL541_RS18515	COG4667	esterase of the alpha-beta hydrolase superfamily
AL541_RS18520	COG2095	MarC family integral membrane protein
AL541_RS18540	COG0489	protein tyrosine kinase activity
AL541_RS18540	COG3206	protein involved in exopolysaccharide biosynthesis
AL541_RS18555	COG0583	DNA-binding transcription factor activity
AL541_RS18565	COG1301	dicarboxylic acid transport
AL541_RS18580	COG3339	Conserved Protein
AL541_RS18585	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AL541_RS18590	COG0700	Nucleoside recognition
AL541_RS18595	COG3366	ferrous iron transmembrane transporter activity
AL541_RS18610	COG0366	Alpha amylase catalytic
AL541_RS18615	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AL541_RS18620	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AL541_RS18625	COG1640	4-alpha-glucanotransferase
AL541_RS18630	COG0058	SHG alpha-glucan phosphorylase activity
AL541_RS18635	COG2909	trisaccharide binding
AL541_RS18650	COG1999	signal sequence binding
AL541_RS18655	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL541_RS18655	COG1263	PTS System
AL541_RS18660	COG1162	GTPase activity
AL541_RS18665	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AL541_RS18670	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AL541_RS18690	COG2356	endonuclease I
AL541_RS18710	COG4580	involved in the transport of maltose and maltodextrins
AL541_RS18720	COG1760	l-serine dehydratase
AL541_RS18760	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AL541_RS18770	COG1609	Transcriptional regulator
AL541_RS18775	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AL541_RS18785	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AL541_RS18785	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AL541_RS18800	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AL541_RS18805	COG1609	Transcriptional regulator
AL541_RS18815	COG2814	Major facilitator Superfamily
AL541_RS18830	COG0739	heme binding
AL541_RS18840	COG0612	Peptidase, M16
AL541_RS18845	COG0840	transmembrane signaling receptor activity
AL541_RS18850	COG1120	ATPase activity
AL541_RS18855	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL541_RS18860	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL541_RS18865	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AL541_RS18870	COG4772	TonB-dependent receptor
AL541_RS18895	COG4264	IucA IucC family
AL541_RS18900	COG0019	diaminopimelate decarboxylase activity
AL541_RS18905	COG1653	transport
AL541_RS18935	COG0826	peptidase U32
AL541_RS18945	COG1136	(ABC) transporter
AL541_RS18950	COG0577	efflux transmembrane transporter activity
AL541_RS18995	COG1764	response to oxidative stress
AL541_RS19000	COG1846	Transcriptional regulator
AL541_RS19010	COG3634	alkyl hydroperoxide reductase activity
AL541_RS19075	COG2258	MOSC domain
AL541_RS19080	COG0513	Belongs to the DEAD box helicase family
AL541_RS19090	COG1132	(ABC) transporter
AL541_RS19130	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AL541_RS19155	COG0259	pyridoxamine-phosphate oxidase activity
AL541_RS19200	COG4166	transmembrane transport
AL541_RS19220	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AL541_RS19225	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL541_RS19225	COG1263	PTS System
AL541_RS19230	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL541_RS19235	COG3340	Belongs to the peptidase S51 family
AL541_RS19255	COG1444	tRNA N-acetyltransferase activity
AL541_RS19280	COG4608	Belongs to the ABC transporter superfamily
AL541_RS19285	COG0444	Belongs to the ABC transporter superfamily
AL541_RS19295	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
AL541_RS19295	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AL541_RS19320	COG0772	Belongs to the SEDS family
AL541_RS19330	COG1136	(ABC) transporter
AL541_RS19350	COG3275	phosphorelay sensor kinase activity
AL541_RS19355	COG3279	Response regulator of the LytR AlgR family
AL541_RS19360	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AL541_RS19385	COG0786	glutamate:sodium symporter activity
AL541_RS19395	COG1131	(ABC) transporter
AL541_RS19400	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL541_RS19405	COG0786	glutamate:sodium symporter activity
AL541_RS19415	COG0363	glucosamine-6-phosphate deaminase activity
AL541_RS19435	COG1741	Belongs to the pirin family
AL541_RS19440	COG2259	Doxx family
AL541_RS19450	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AL541_RS19450	COG2169	Transcriptional regulator
AL541_RS19455	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AL541_RS19465	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AL541_RS19490	COG0596	Alpha beta hydrolase
AL541_RS19505	COG3123	guanosine phosphorylase activity
AL541_RS19520	COG0534	Mate efflux family protein
AL541_RS19525	COG0564	pseudouridine synthase activity
AL541_RS19540	COG0583	DNA-binding transcription factor activity
AL541_RS19545	COG0561	phosphatase activity
AL541_RS19555	COG2199	diguanylate cyclase activity
AL541_RS19570	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AL541_RS19575	COG2162	N-hydroxyarylamine O-acetyltransferase activity
AL541_RS19580	COG0583	DNA-binding transcription factor activity
AL541_RS19585	COG2375	cellular response to nickel ion
AL541_RS19615	COG1357	PFAM Pentapeptide repeats (8 copies)
AL541_RS19620	COG3047	cAMP biosynthetic process
AL541_RS19630	COG2814	Major facilitator Superfamily
AL541_RS19680	COG3835	regulator
AL541_RS19685	COG2610	gluconate transmembrane transporter activity
AL541_RS19690	COG1929	Belongs to the glycerate kinase type-1 family
AL541_RS19695	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL541_RS19715	COG0456	acetyltransferase
AL541_RS19730	COG1028	Short-chain dehydrogenase reductase Sdr
AL541_RS19735	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL541_RS19740	COG3005	denitrification pathway
AL541_RS19745	COG0243	molybdopterin cofactor binding
AL541_RS19765	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AL541_RS19770	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL541_RS19775	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL541_RS19780	COG1116	anion transmembrane transporter activity
AL541_RS19785	COG0351	phosphomethylpyrimidine kinase
AL541_RS19790	COG0312	modulator of DNA gyrase
AL541_RS19795	COG0312	modulator of DNA gyrase
AL541_RS19800	COG1901	pseudouridine methyltransferase
AL541_RS19860	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AL541_RS19870	COG0584	glycerophosphoryl diester phosphodiesterase
AL541_RS19875	COG0745	RESPONSE REGULATOR receiver
AL541_RS19880	COG2205	protein histidine kinase activity
AL541_RS19895	COG0811	peptide transport
AL541_RS19900	COG0811	peptide transport
AL541_RS19905	COG0848	biopolymer transport protein
AL541_RS19955	COG0803	Belongs to the bacterial solute-binding protein 9 family
AL541_RS19960	COG1121	(ABC) transporter
AL541_RS19965	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AL541_RS19980	COG1770	oligopeptidase
AL541_RS19985	COG2814	Major facilitator Superfamily
AL541_RS19995	COG1166	arginine decarboxylase activity
AL541_RS20005	COG0189	ligase activity
AL541_RS20005	COG4067	protein conserved in archaea
AL541_RS20010	COG0189	ligase activity
AL541_RS20035	COG0583	DNA-binding transcription factor activity
AL541_RS20055	COG4191	Histidine kinase
AL541_RS20065	COG3706	GGDEF domain
AL541_RS20090	COG0579	oxidoreductase
AL541_RS20095	COG3179	chitinase
AL541_RS20115	COG1294	oxidase, subunit
AL541_RS20120	COG1271	oxidase subunit
AL541_RS20130	COG3033	Beta-eliminating lyase
AL541_RS20150	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AL541_RS20165	COG3706	GGDEF domain
AL541_RS20180	COG3706	GGDEF domain
AL541_RS20185	COG0415	Belongs to the DNA photolyase family
AL541_RS20190	COG3046	protein related to deoxyribodipyrimidine photolyase
AL541_RS20205	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL541_RS20205	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL541_RS20210	COG1765	OsmC-like protein
AL541_RS20215	COG0110	maltose O-acetyltransferase activity
AL541_RS20255	COG1011	Hydrolase
AL541_RS20270	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
AL541_RS20280	COG2067	long-chain fatty acid transport protein
AL541_RS20290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL541_RS20295	COG1136	(ABC) transporter
AL541_RS20295	COG0577	efflux transmembrane transporter activity
AL541_RS20310	COG1309	transcriptional regulator
AL541_RS20315	COG3240	lipase activity
AL541_RS20345	COG1609	Transcriptional regulator
AL541_RS20355	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AL541_RS20365	COG1840	ABC-type Fe3 transport system, periplasmic component
AL541_RS20370	COG3842	ATPase activity
AL541_RS20395	COG2990	Protein conserved in bacteria
AL541_RS20405	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL541_RS20410	COG2866	Carboxypeptidase
AL541_RS20420	COG0583	DNA-binding transcription factor activity
AL541_RS20435	COG1760	l-serine dehydratase
AL541_RS20455	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AL541_RS20460	COG0741	lytic transglycosylase activity
AL541_RS20460	COG1388	LysM domain
AL541_RS20480	COG1815	bacterial-type flagellum-dependent cell motility
AL541_RS20485	COG1558	bacterial-type flagellum-dependent cell motility
AL541_RS20500	COG4787	bacterial-type flagellum-dependent cell motility
AL541_RS20505	COG4786	Flagellar basal body rod
AL541_RS20510	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AL541_RS20515	COG1706	bacterial-type flagellum-dependent cell motility
AL541_RS20525	COG1256	bacterial-type flagellum assembly
AL541_RS20525	COG4786	Flagellar basal body rod
AL541_RS20550	COG1304	FMN binding
AL541_RS20565	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AL541_RS20570	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AL541_RS20575	COG0459	protein refolding
AL541_RS20585	COG1280	lysine exporter protein (LysE YggA)
AL541_RS20605	COG1309	transcriptional regulator
AL541_RS20615	COG4303	Ethanolamine ammonia lyase large subunit
AL541_RS20620	COG4302	ethanolamine ammonia-lyase activity
AL541_RS20625	COG0531	amino acid
AL541_RS20630	COG2070	2-Nitropropane dioxygenase
AL541_RS20640	COG1349	DNA-binding transcription factor activity
AL541_RS20655	COG1335	isochorismatase
AL541_RS20665	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AL541_RS20690	COG0583	DNA-binding transcription factor activity
AL541_RS20705	COG3713	MltA-interacting MipA family protein
AL541_RS20710	COG3015	lipoprotein NlpE involved in copper resistance
AL541_RS20715	COG3448	diguanylate cyclase activity
AL541_RS20715	COG4175	Glycine betaine
AL541_RS20720	COG4176	ABC-type proline glycine betaine transport system permease component
AL541_RS20730	COG1342	Belongs to the UPF0251 family
AL541_RS20765	COG4948	Mandelate Racemase Muconate Lactonizing
AL541_RS20775	COG0583	DNA-binding transcription factor activity
AL541_RS20810	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AL541_RS20815	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AL541_RS20845	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL541_RS20865	COG3842	ATPase activity
AL541_RS20895	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AL541_RS20920	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AL541_RS20925	COG2197	response regulator
AL541_RS20940	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AL541_RS20945	COG0252	asparaginase activity
AL541_RS20950	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AL541_RS20955	COG0583	DNA-binding transcription factor activity
AL541_RS20970	COG3122	Protein conserved in bacteria
AL541_RS20975	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AL541_RS20980	COG1012	belongs to the aldehyde dehydrogenase family
AL541_RS20985	COG1522	sequence-specific DNA binding
AL541_RS20990	COG3608	succinylglutamate desuccinylase aspartoacylase
AL541_RS20995	COG0006	proline dipeptidase activity
AL541_RS21000	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL541_RS21010	COG1028	Short-chain dehydrogenase reductase Sdr
AL541_RS21020	COG1063	alcohol dehydrogenase
AL541_RS21025	COG1902	pentaerythritol trinitrate reductase activity
AL541_RS21040	COG0583	DNA-binding transcription factor activity
AL541_RS21050	COG0513	Belongs to the DEAD box helicase family
AL541_RS21080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL541_RS21085	COG2207	Transcriptional regulator
AL541_RS21085	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AL541_RS21090	COG0583	DNA-binding transcription factor activity
AL541_RS21095	COG0300	oxidoreductase activity
AL541_RS21110	COG3746	phosphate-selective porin O and P
AL541_RS21125	COG1028	Short-chain dehydrogenase reductase Sdr
AL541_RS21130	COG1404	Belongs to the peptidase S8 family
AL541_RS21140	COG0583	DNA-binding transcription factor activity
AL541_RS21145	COG4771	TonB-dependent receptor
AL541_RS21165	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL541_RS21165	COG1263	PTS System
AL541_RS21170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL541_RS21175	COG1621	beta-fructofuranosidase activity
AL541_RS21180	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AL541_RS21190	COG0625	glutathione transferase activity
AL541_RS21200	COG1686	Belongs to the peptidase S11 family
AL541_RS21215	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AL541_RS21230	COG1278	Cold shock
AL541_RS21235	COG1741	Belongs to the pirin family
AL541_RS21240	COG4667	esterase of the alpha-beta hydrolase superfamily
AL541_RS21260	COG2194	sulfuric ester hydrolase activity
AL541_RS21265	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AL541_RS21275	COG2205	protein histidine kinase activity
AL541_RS21280	COG0745	RESPONSE REGULATOR receiver
AL541_RS21295	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AL541_RS21315	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AL541_RS21325	COG2814	Major facilitator Superfamily
AL541_RS21340	COG1418	mRNA catabolic process
AL541_RS21345	COG0402	S-adenosylhomocysteine deaminase activity
AL541_RS21350	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AL541_RS21355	COG2239	Acts as a magnesium transporter
AL541_RS21360	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AL541_RS21365	COG1566	PFAM secretion protein HlyD family protein
AL541_RS21390	COG0745	RESPONSE REGULATOR receiver
AL541_RS21395	COG2205	protein histidine kinase activity
AL541_RS21410	COG0531	amino acid
AL541_RS21425	COG0583	DNA-binding transcription factor activity
AL541_RS21445	COG5002	protein histidine kinase activity
AL541_RS21445	COG2205	protein histidine kinase activity
AL541_RS21445	COG0784	Response regulator, receiver
AL541_RS21465	COG3132	Protein of unknown function, DUF480
AL541_RS21470	COG2827	Endonuclease containing a URI domain
AL541_RS21480	COG1879	ABC-type sugar transport system periplasmic component
AL541_RS21485	COG2205	protein histidine kinase activity
AL541_RS21485	COG0784	Response regulator, receiver
AL541_RS21490	COG1846	Transcriptional regulator
AL541_RS21545	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL541_RS21550	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL541_RS21560	COG1280	lysine exporter protein (LysE YggA)
AL541_RS21570	COG0183	Belongs to the thiolase family
AL541_RS21580	COG3243	poly(R)-hydroxyalkanoic acid synthase
AL541_RS21590	COG3005	denitrification pathway
AL541_RS21600	COG0243	molybdopterin cofactor binding
AL541_RS21610	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL541_RS21615	COG3850	Histidine kinase
AL541_RS21620	COG2197	response regulator
AL541_RS21635	COG2195	Cleaves the N-terminal amino acid of tripeptides
AL541_RS21655	COG0840	transmembrane signaling receptor activity
AL541_RS21665	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL541_RS21680	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AL541_RS21685	COG2814	Major facilitator Superfamily
AL541_RS21695	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AL541_RS21700	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AL541_RS21720	COG2897	thiosulfate sulfurtransferase activity
AL541_RS21755	COG0038	chloride channel
AL541_RS21770	COG4989	oxidoreductase activity
AL541_RS21785	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AL541_RS21785	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AL541_RS21815	COG3537	Alpha-1,2-mannosidase
AL541_RS21820	COG3537	Alpha-1,2-mannosidase
AL541_RS21830	COG3537	Alpha-1,2-mannosidase
AL541_RS21835	COG3537	Alpha-1,2-mannosidase
AL541_RS21840	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL541_RS21855	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL541_RS21855	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL541_RS21855	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL541_RS21860	COG2207	Transcriptional regulator
AL541_RS21870	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL541_RS21875	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL541_RS21900	COG0739	heme binding
AL541_RS21925	COG2204	response regulator
AL541_RS21940	COG3501	Rhs element vgr protein
AL541_RS21965	COG0515	serine threonine protein kinase
AL541_RS22000	COG1522	sequence-specific DNA binding
AL541_RS22045	COG3501	Rhs element vgr protein
AL541_RS22045	COG3409	Peptidoglycan-binding domain 1 protein
AL541_RS22065	COG2814	Major facilitator Superfamily
AL541_RS22075	COG0583	DNA-binding transcription factor activity
AL541_RS22080	COG4221	oxidoreductase activity
AL541_RS22085	COG0589	response to stress
AL541_RS22095	COG2111	Na H antiporter
AL541_RS22095	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AL541_RS22100	COG1006	Multisubunit Na H antiporter MnhC subunit
AL541_RS22105	COG0651	ATP synthesis coupled electron transport
AL541_RS22110	COG1863	multisubunit Na H antiporter MnhE subunit
AL541_RS22115	COG2212	antiporter activity
AL541_RS22120	COG1320	monovalent cation:proton antiporter activity
AL541_RS22125	COG2188	Transcriptional regulator
AL541_RS22130	COG1486	melibiose metabolic process
AL541_RS22135	COG1263	PTS System
AL541_RS22135	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL541_RS22140	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AL541_RS22170	COG1022	Amp-dependent synthetase and ligase
AL541_RS22200	COG0500	methyltransferase
AL541_RS22230	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AL541_RS22245	COG3527	Alpha-acetolactate decarboxylase
AL541_RS22255	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL541_RS22270	COG1294	oxidase, subunit
AL541_RS22275	COG1271	oxidase subunit
AL541_RS22280	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL541_RS22285	COG0110	maltose O-acetyltransferase activity
AL541_RS22295	COG3264	Mechanosensitive ion channel
AL541_RS22295	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AL541_RS22310	COG4770	biotin carboxylase activity
AL541_RS22320	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AL541_RS22325	COG1960	acyl-CoA dehydrogenase activity
AL541_RS22335	COG0183	Belongs to the thiolase family
AL541_RS22345	COG1960	acyl-CoA dehydrogenase activity
AL541_RS22350	COG1024	Enoyl-CoA hydratase
AL541_RS22365	COG1028	Short-chain dehydrogenase reductase Sdr
AL541_RS22375	COG1309	transcriptional regulator
AL541_RS22380	COG1012	belongs to the aldehyde dehydrogenase family
AL541_RS22395	COG4176	ABC-type proline glycine betaine transport system permease component
AL541_RS22400	COG0517	IMP dehydrogenase activity
AL541_RS22400	COG4175	Glycine betaine
AL541_RS22415	COG0330	HflC and HflK could
AL541_RS22430	COG0784	Response regulator, receiver
AL541_RS22430	COG2205	protein histidine kinase activity
AL541_RS22440	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AL541_RS22495	COG5001	Diguanylate cyclase
AL541_RS22500	COG1869	D-ribose catabolic process
AL541_RS22505	COG1129	ABC transporter
AL541_RS22510	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL541_RS22515	COG1879	ABC-type sugar transport system periplasmic component
AL541_RS22520	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL541_RS22525	COG1609	Transcriptional regulator
AL541_RS22540	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
AL541_RS22550	COG4607	ABC-type enterochelin transport system periplasmic component
AL541_RS22555	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL541_RS22560	COG4605	iron ion homeostasis
AL541_RS22565	COG4604	ABC transporter, ATP-binding protein
AL541_RS22570	COG0789	Transcriptional regulator
AL541_RS22580	COG4771	TonB-dependent receptor
AL541_RS22580	COG1629	transport
AL541_RS22615	COG1289	transmembrane transporter activity
AL541_RS22620	COG0210	DNA helicase
AL541_RS22625	COG1803	Methylglyoxal synthase
AL541_RS22630	COG1879	ABC-type sugar transport system periplasmic component
AL541_RS22635	COG2205	protein histidine kinase activity
AL541_RS22635	COG0784	Response regulator, receiver
AL541_RS22635	COG2198	Histidine kinase
AL541_RS22650	COG0745	RESPONSE REGULATOR receiver
AL541_RS22655	COG3119	arylsulfatase activity
AL541_RS22665	COG3119	arylsulfatase activity
AL541_RS22670	COG0641	radical SAM
AL541_RS22675	COG0714	Associated with various cellular activities
AL541_RS22705	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AL541_RS22710	COG0583	DNA-binding transcription factor activity
AL541_RS22715	COG1597	lipid kinase activity
AL541_RS22720	COG3111	PFAM Bacterial OB fold (BOF) protein
AL541_RS22745	COG3069	C4-dicarboxylate transmembrane transporter activity
AL541_RS22755	COG0456	acetyltransferase
AL541_RS22755	COG1214	PFAM Peptidase M22, glycoprotease
AL541_RS22775	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AL541_RS22780	COG0784	Response regulator, receiver
AL541_RS22780	COG2205	protein histidine kinase activity
AL541_RS22785	COG3300	MHYT domain
AL541_RS22785	COG5001	Diguanylate cyclase
AL541_RS22790	COG2197	response regulator
AL541_RS22795	COG3706	GGDEF domain
AL541_RS22805	COG2197	response regulator
AL541_RS22815	COG0784	Response regulator, receiver
AL541_RS22815	COG0835	chemotaxis
AL541_RS22830	COG2962	Rard protein
AL541_RS22850	COG2076	Multidrug Resistance protein
AL541_RS22885	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AL541_RS22890	COG5642	Protein of unknown function (DUF2384)
AL541_RS22900	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AL541_RS22900	COG2755	lipolytic protein G-D-S-L family
AL541_RS22910	COG1902	pentaerythritol trinitrate reductase activity
AL541_RS22915	COG0346	lactoylglutathione lyase activity
AL541_RS22935	COG2239	Acts as a magnesium transporter
AL541_RS22970	COG0242	peptide deformylase activity
AL541_RS23015	COG2176	DNA-directed DNA polymerase activity
AL541_RS23070	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL541_RS23075	COG0697	spore germination
AL541_RS23080	COG0583	DNA-binding transcription factor activity
AL541_RS23085	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AL541_RS23095	COG0346	lactoylglutathione lyase activity
AL541_RS23105	COG0509	glycine decarboxylation via glycine cleavage system
AL541_RS23110	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AL541_RS23120	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AL541_RS23150	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AL541_RS23150	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL541_RS23150	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL541_RS23155	COG1105	Belongs to the carbohydrate kinase PfkB family
AL541_RS23160	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL541_RS23160	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL541_RS23165	COG1609	Transcriptional regulator
AL541_RS23180	COG2199	diguanylate cyclase activity
AL541_RS23180	COG2203	Gaf domain
AL541_RS23180	COG2200	EAL domain
AL541_RS23185	COG0765	amino acid transport
AL541_RS23190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL541_RS23195	COG0765	amino acid transport
AL541_RS23200	COG1126	abc transporter atp-binding protein
AL541_RS23210	COG1979	alcohol dehydrogenase
AL541_RS23215	COG2207	Transcriptional regulator
AL541_RS23230	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AL541_RS23235	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AL541_RS23240	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL541_RS23255	COG0546	phosphoglycolate phosphatase activity
AL541_RS23280	COG0513	Belongs to the DEAD box helicase family
AL541_RS23300	COG3038	cytochrome b561
AL541_RS23305	COG2353	YceI-like domain
AL541_RS23310	COG2116	formate transmembrane transporter activity
AL541_RS23315	COG0583	DNA-binding transcription factor activity
AL541_RS23325	COG3593	DNA synthesis involved in DNA repair
AL541_RS23330	COG0737	Belongs to the 5'-nucleotidase family
AL541_RS23355	COG2267	carboxylic ester hydrolase activity
AL541_RS23360	COG2067	long-chain fatty acid transport protein
AL541_RS23375	COG2050	protein possibly involved in aromatic compounds catabolism
AL541_RS23385	COG4533	DNA binding
AL541_RS23420	COG3300	MHYT domain
AL541_RS23420	COG5001	Diguanylate cyclase
AL541_RS23425	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AL541_RS23435	COG4181	ATPase activity
AL541_RS23440	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AL541_RS23450	COG1984	allophanate hydrolase subunit 2
AL541_RS23455	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AL541_RS23460	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AL541_RS23465	COG5001	Diguanylate cyclase
AL541_RS23465	COG5002	protein histidine kinase activity
AL541_RS23465	COG3447	MASE1 domain protein
AL541_RS23485	COG0583	DNA-binding transcription factor activity
AL541_RS23490	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL541_RS23490	COG1042	CoA-binding domain protein
AL541_RS23490	COG0045	succinate-CoA ligase (ADP-forming) activity
AL541_RS23500	COG1181	Belongs to the D-alanine--D-alanine ligase family
AL541_RS23510	COG0023	Translation Initiation Factor
AL541_RS23670	COG3140	Belongs to the UPF0181 family
AL541_RS23695	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AL541_RS23700	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AL541_RS23720	COG5001	Diguanylate cyclase
AL541_RS23720	COG3706	GGDEF domain
AL541_RS23720	COG4251	negative regulation of phosphorylation
AL541_RS23720	COG2203	Gaf domain
AL541_RS23730	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AL541_RS23735	COG4149	molybdate abc transporter
AL541_RS23740	COG0725	ABC transporter, periplasmic molybdate-binding protein
AL541_RS23750	COG3111	PFAM Bacterial OB fold (BOF) protein
AL541_RS23760	COG0189	ligase activity
AL541_RS23760	COG4067	protein conserved in archaea
AL541_RS23770	COG2207	Transcriptional regulator
AL541_RS23775	COG0534	Mate efflux family protein
AL541_RS23780	COG0602	queuosine metabolic process
AL541_RS23785	COG1328	CTP reductase activity
AL541_RS23820	COG1794	racemase activity, acting on amino acids and derivatives
AL541_RS23825	COG0384	phenazine biosynthesis protein PhzF
AL541_RS23840	COG0243	molybdopterin cofactor binding
AL541_RS23850	COG0583	DNA-binding transcription factor activity
AL541_RS23855	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AL541_RS23865	COG2197	response regulator
AL541_RS23870	COG3851	Histidine kinase
AL541_RS23875	COG2271	Major facilitator Superfamily
AL541_RS23900	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AL541_RS23905	COG3118	belongs to the thioredoxin family
AL541_RS23945	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AL541_RS23965	COG2116	formate transmembrane transporter activity
AL541_RS23975	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AL541_RS23980	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AL541_RS24005	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL541_RS24060	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AL541_RS24075	COG0277	FAD linked oxidase domain protein
AL541_RS24080	COG0583	DNA-binding transcription factor activity
AL541_RS24095	COG2425	protein containing a von Willebrand factor type A (vWA) domain
AL541_RS24110	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
AL541_RS24120	COG1288	antiporter activity
AL541_RS24130	COG3040	lipid binding
AL541_RS24140	COG0419	ATPase involved in DNA repair
AL541_RS24145	COG0420	3'-5' exonuclease activity
AL541_RS24215	COG0631	protein serine/threonine phosphatase activity
AL541_RS24250	COG0515	serine threonine protein kinase
AL541_RS24250	COG2815	serine threonine protein kinase
AL541_RS24300	COG2146	nitrite reductase [NAD(P)H] activity
AL541_RS24300	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AL541_RS24305	COG1116	anion transmembrane transporter activity
AL541_RS24310	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL541_RS24315	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL541_RS24315	COG1116	anion transmembrane transporter activity
AL541_RS24345	COG0243	molybdopterin cofactor binding
AL541_RS24355	COG0814	amino acid
AL541_RS24430	COG2847	Copper chaperone PCu(A)C
AL541_RS24435	COG1028	Short-chain dehydrogenase reductase Sdr
AL541_RS24440	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AL541_RS24450	COG0800	Aldolase
AL541_RS24455	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL541_RS24460	COG1917	Cupin 2, conserved barrel domain protein
AL541_RS24505	COG2186	Transcriptional regulator
AL541_RS24510	COG2186	Transcriptional regulator
AL541_RS24515	COG0517	IMP dehydrogenase activity
AL541_RS24520	COG2176	DNA-directed DNA polymerase activity
AL541_RS24525	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AL541_RS24590	COG4160	amino acid transport
AL541_RS24595	COG4215	(ABC) transporter
AL541_RS24600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL541_RS24605	COG1126	abc transporter atp-binding protein
AL541_RS24635	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AL541_RS24645	COG1012	belongs to the aldehyde dehydrogenase family
AL541_RS24660	COG0446	pyridine nucleotide-disulphide oxidoreductase
AL541_RS24660	COG1902	pentaerythritol trinitrate reductase activity
AL541_RS24665	COG0109	protoheme IX farnesyltransferase activity
AL541_RS24670	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AL541_RS24675	COG1845	cytochrome c oxidase, subunit III
AL541_RS24680	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AL541_RS24685	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AL541_RS24690	COG1028	Short-chain dehydrogenase reductase Sdr
AL541_RS24700	COG1024	Enoyl-CoA hydratase
AL541_RS24705	COG1024	Enoyl-CoA hydratase
AL541_RS24720	COG0183	Belongs to the thiolase family
AL541_RS24730	COG1960	acyl-CoA dehydrogenase activity
AL541_RS24735	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AL541_RS24740	COG1024	Enoyl-CoA hydratase
AL541_RS24765	COG2095	MarC family integral membrane protein
AL541_RS24785	COG0523	cobalamin synthesis protein
AL541_RS24795	COG0739	heme binding
AL541_RS24800	COG2988	succinylglutamate desuccinylase activity
AL541_RS24805	COG0523	cobalamin synthesis protein
AL541_RS24815	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AL541_RS24820	COG0735	belongs to the Fur family
AL541_RS24835	COG0730	response to heat
AL541_RS24850	COG1073	alpha beta
AL541_RS24855	COG1073	alpha beta
AL541_RS24865	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AL541_RS24880	COG0513	Belongs to the DEAD box helicase family
AL541_RS24885	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
AL541_RS24920	COG1119	ATPase activity
AL541_RS24925	COG2200	EAL domain
AL541_RS24945	COG0513	Belongs to the DEAD box helicase family
AL541_RS24950	COG0523	cobalamin synthesis protein
AL541_RS24960	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
AL541_RS24970	COG1278	Cold shock
AL541_RS24980	COG0133	tryptophan synthase activity
AL541_RS24990	COG4628	conserved protein (DUF2132)
AL541_RS24995	COG0513	Belongs to the DEAD box helicase family
AL541_RS25000	COG2814	Major facilitator Superfamily
AL541_RS25015	COG3530	Putative quorum-sensing-regulated virulence factor
AL541_RS25040	COG3186	Phenylalanine-4-hydroxylase
AL541_RS25045	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AL541_RS25050	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AL541_RS25070	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AL541_RS25075	COG1454	alcohol dehydrogenase
AL541_RS25080	COG2133	pyrroloquinoline quinone binding
AL541_RS25085	COG1619	proteins homologs of microcin C7 resistance protein MccF
AL541_RS25095	COG0783	Belongs to the Dps family
AL541_RS25100	COG0840	transmembrane signaling receptor activity
AL541_RS25125	COG2205	protein histidine kinase activity
AL541_RS25125	COG0784	Response regulator, receiver
AL541_RS25130	COG1538	Outer membrane efflux protein
AL541_RS25140	COG1132	(ABC) transporter
AL541_RS25155	COG2199	diguanylate cyclase activity
AL541_RS25160	COG3036	rescue of stalled ribosome
AL541_RS25165	COG1278	Cold shock
AL541_RS25195	COG0545	Peptidyl-prolyl cis-trans isomerase
AL541_RS25200	COG0109	protoheme IX farnesyltransferase activity
AL541_RS25205	COG1612	heme a metabolic process
AL541_RS25225	COG1845	cytochrome c oxidase, subunit III
AL541_RS25230	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
AL541_RS25235	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AL541_RS25240	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AL541_RS25245	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AL541_RS25255	COG1280	lysine exporter protein (LysE YggA)
AL541_RS25275	COG0179	Fumarylacetoacetate (FAA) hydrolase
AL541_RS25290	COG0697	spore germination
AL541_RS25310	COG2814	Major facilitator Superfamily
AL541_RS25315	COG0583	DNA-binding transcription factor activity
AL541_RS25320	COG5001	Diguanylate cyclase
AL541_RS25325	COG0739	heme binding
AL541_RS25350	COG3314	Sporulation integral membrane protein YlbJ
AL541_RS25365	COG0814	amino acid
AL541_RS25390	COG4989	oxidoreductase activity
AL541_RS25415	COG1733	regulation of RNA biosynthetic process
AL541_RS25430	COG0798	PFAM Bile acid sodium symporter
AL541_RS25440	COG1881	PFAM PEBP family protein
AL541_RS25455	COG1131	(ABC) transporter
AL541_RS25460	COG0842	Transport permease protein
AL541_RS25470	COG3383	formate dehydrogenase (NAD+) activity
AL541_RS25490	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family